| P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
|---|
| 7.884e-46 | -103.85 | cytoplasm | cellular component | GO:0005737 | 10396 | 1847 | 17570 | 2579 |
HECA,IBTK,GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,CCNO,TRAPPC8,TGOLN2,ISOC2,LACTB2,DPP8,SNX9,SPSB1,CARD10,GRM5,NPM2,CDKN2C,NAPG,MUC4,UBE2T,DNM2,CRY2,PPP1CA,TIAM1,CPE,MGAT5,DNAAF3,NEK4,FBXL16,DSTN,UXT,CDA,TMEM98,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,GINS4,LCP1,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MPRIP,MID1IP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,HSPB1,STARD13,ANXA11,NXT2,SCN5A,GGA1,SEC61G,MTL5,RAB23,GPSM2,COX6C,FAM21C,RABGGTA,ATG4A,MARCH8,FLII,RAC2,FRY,PAIP2B,ATP5H,FLRT3,FBXO7,RANBP1,FBXL14,PCYOX1,SLAIN2,CADPS2,FAM84B,MYDGF,PANX2,MAPK7,MOXD1,DGKG,MYLIP,NUP85,PHKG2,TTLL1,PPP6R1,MCCC2,HPS3,PQLC3,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,PSMA4,GNA11,SFXN5,PLIN5,FNTA,ETS2,APMAP,DGAT2,CLMN,STK39,CFAP20,TMEM173,RUSC1,DOCK9,DMPK,NQO1,LFNG,INPP5D,APOO,PTTG1,C5orf30,MAPK4,MGST2,MVB12B,MOCS1,APPBP2,RCN1,MUC16,CDH1,SH3BP1,XYLT2,TAX1BP3,DLG3,RASGEF1A,ZNF365,MYT1,SNX10,MX1,SNX8,SEC61B,ERMP1,COL6A2,RIPK2,APOBEC3D,AGPS,PFKFB2,SEPT6,PTPN9,SAT1,VPS4B,HTATIP2,SYP,DNAJB14,SNX12,TRIM7,COX20,GABARAPL1,ALDH3B1,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,PNPLA6,SLC25A30,ISOC1,MAPK12,CTHRC1,MZT1,HSP90B1,GCAT,CKAP2,BACE1,TRAF2,DCAF7,CCM2,BIK,SDC4,HABP4,FLOT1,CTSZ,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,SLC25A45,PDCD10,FUT2,GPC3,MGAT4A,FAM20B,CST3,TUBGCP6,KLC3,BAX,IGFBP2,MED22,PARP9,ACBD5,OPLAH,PLSCR1,TACC1,PIK3R1,DUSP23,MRS2,UBE2A,AK4,RAB3IP,PIM3,RGPD5,LDLRAP1,PROM1,RPL12,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,FAM3C,PLA2G15,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,WDR45B,ACOT7,ILDR1,TNK1,EPAS1,CNOT8,ARFGEF1,LMCD1,PHOSPHO1,DNAJB11,NDRG2,F11R,ITPR2,GALM,MGAT5B,SPTB,SLC9A3R2,FANCI,PLS3,CPNE2,INPP5E,BTG3,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,P4HB,ARL1,PAPSS1,PSMC2,SLC44A1,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,KRT80,KCNIP3,MARK1,PTPN18,CELSR2,STAU2,NFE2L1,CCBL2,CKAP2L,ARFRP1,SESN1,DZIP1L,TNS4,TRIM9,HS6ST1,PLEKHG6,PI4K2B,AGPAT2,KLF12,HOXA9,ARRDC1,KPNA2,MYL12B,RRAGD,RUNX2,LMTK3,USH1C,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,PDCL,PSMD7,SORBS3,ADCK5,RAB6A,NCKAP1,RSAD1,ANO1,B4GALNT1,TNS3,UBE2Q2,TIMP1,RINL,KIF13B,TBCD,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,WNT3A,NTN1,MPHOSPH9,CKAP4,DPYSL5,RGMB,MGAT4B,EMC2,STRADB,SCRIB,PDK3,BCL2L13,PRX,NMT2,C18orf8,CDK5R1,RASGRP2,FA2H,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,CDAN1,RAD21,HOXB7,TP53,P2RX7,RHPN2,STIL,PCBP1,EMP2,BCAP31,TMSB15B,SYTL2,TTC21B,PDGFA,WDR44,TACC2,PLK4,ZDHHC23,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,ACO1,DAG1,CFAP36,ATP13A2,PTGS2,TAPBP,IDE,PAFAH1B3,STK38,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ARHGAP4,ST3GAL1,BTBD6,FAM134B,ARFGEF3,BIN1,CMAS,PINK1,CPEB4,TAB3,CTSB,SCD5,HAL,MCTP2,CDCA8,ERCC6L,ERI2,HMGN3,AIP,LBR,VPS26A,PARM1,DNAJB9,FZD6,SH2D4A,M6PR,ZDHHC21,CDK16,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,HMGCL,CPLX1,SYK,GCNT1,DUSP1,NFE2L3,P2RX4,HES1,RHOA,GUSB,PLAUR,CRIP2,PRICKLE1,DPP9,STMN3,MAML2,GGH,COL7A1,TXNDC11,RNPEP,BBS2,DGKE,USP6,BCL10,CNOT2,DDAH1,SCG2,NIPSNAP3A,E2F1,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,PNISR,SSH1,HSPG2,TMEM86B,TSC22D3,CUL1,C1orf198,PSME1,NANS,CAMK1D,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,PAK6,TYMP,CYP1A1,ANKS6,STIM1,OSBPL3,PALD1,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,TACSTD2,MARCH2,METAP2,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,POR,RAB2B,GDE1,SH2D3C,PPP2R4,BMP1,MAPK13,SPRY4,WBSCR27,F2RL1,SLC31A2,FGD1,CDKN1C,SCOC,DHPS,TBC1D1,THEMIS2,TMEM55B,PRKAA1,AKAP17A,TXNDC9,HERC6,APBA1,PDXDC1,PSIP1,MESDC2,C9orf69,CALR,DOPEY2,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,CEP89,ADCK3,LPGAT1,CALM1,WHSC1,PYGL,NPC2,ATP8B3,ANTXR1,PDE11A,NT5C2,AP1AR,PLEKHH2,FAM64A,FAAH,PELI2,WDR19,ZDHHC20,AGBL5,FAM83D,APPL2,ARAP1,CABIN1,KLK7,SAMD8,PLIN3,PER3,HOOK1,IFIH1,EHD1,FOXO6,SPRED1,KIF3C,DLGAP5,TCTN2,CAPN12,REPS2,GPR107,THRA,DDIT4L,CERCAM,RALBP1,NDRG1,CCDC110,ATP2C2,FTH1,BCL2L1,FLT3,CYP39A1,ZFYVE9,EPS8L2,EPM2A,CD46,NOV,CCNA2,ACAP2,RALB,RNASEH2A,PDE4D,EPHB4,OSBPL7,TSPAN1,SULT2B1,FLOT2,NAGA,SEMA3B,ATG4D,DOCK4,COG2,CYB5R2,PANK1,UTRN,CLSTN1,KIF1C,PKMYT1,CBL,B3GALNT2,ITPR3,TRIQK,ATP10D,CEP162,ZMPSTE24,DDOST,ACAD10,NGFRAP1,TRIOBP,SLC27A3,AREL1,CBX7,COBL,MAMDC2,PRKAR1A,IGFBP6,CENPI,EPS8,NES,HERC5,PLD2,FBXO6,SPDL1,DNAH3,EFNB1,COX7A2,HLA-A,WWP2,SLC25A36,CKAP5,GOLGA2P5,RNF128,FUT8,DRAM1,CD9,CITED2,TTPA,MSH6,FARP2,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,PAPD7,DIAPH2,FBXO9,UBAC1,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,CRTC2,DCTN6,CDK5RAP1,TIMP3,ACADSB,FGFR2,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,COMMD5,MAP1LC3B,ERP29,SLC8B1,ECI1,TRIM68,ZFYVE16,RAB15,HSF2,CASC4,ARHGEF37,METTL7A,CDKL5,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,IL1RAP,STK35,LAMP3,CERS2,CYP1B1,NLRP4,CXXC5,CENPA,LAP3,ITCH,ACBD3,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SH3GLB2,CAB39,SP6,GLA,CHPT1,NRGN,CAPN1,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,PPP1R12A,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,QSOX2,B3GALNT1,SPP1,NOXA1,CES2,FAM20C,PFKL,OCRL,COL6A1,SUCO,PRKCI,SRP54,BRAT1,NPTN,HLA-C,ZRANB1,GAD1,CCDC88A,MDFI,SNX7,TPGS2,ELK3,SPA17,PDE5A,PRRC1,NUBP1,C3orf58,STEAP1,RANBP9,RHPN1,INSR,UAP1,TMEM30A,SH3BP4,RAB31,CTSA,SHROOM2,JAK3,TOB1,APOL2,COL16A1,AFAP1,SNX30,DRD1,LMO7,CCNE2,NBPF1,LZTFL1,DYNLRB1,SORBS1,PAX6,SOD2,PDIA5,COL18A1,SAYSD1,PHLDA1,EXT2,CYP4F11,COX14,KIF14,REEP1,FABP6,ZBTB49,DIXDC1,ECE1,EPB41L4B,NFKB2,ETHE1,UPF3A,EBAG9,CHP1,SEPHS1,SOAT1,RFK,C3orf52,MRPS35,GLO1,TMTC2,CD40,CDC25C,CASP4,PDHX,ARHGAP35,SOCS3,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,SPTBN5,RCAN2,MAD2L1BP,ABCA1,KDELC2,GLIS3,FBLIM1,GCLM,ENO2,ARHGEF11,CIT,SH3D19,ARHGEF7,SERPINB9,TGFBR1,COL4A5,TRIB2,NTAN1,RBP7,XPR1,ITGA2B,HDAC9,TMEM63A,SYDE2,KIF5B,TOP2A,MZT2A,CARD8,ADRBK1,LLGL2,A4GALT,RRBP1,ZDHHC13,ACTA2,ARVCF,KANK2,CLIP2,RPGR,SLC35A1,MYO5A,B3GALT6,PGM1,DCAF6,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,NDRG3,ARHGAP24,CTSL,CASP7,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,CSGALNACT1,DTX4,UACA,ARRB1,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,NGEF,DOC2A,ACACB,KLK10,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,MMADHC,FBXO2,XIAP,DHX8,LGI3,IL18,CNTROB,SYTL4,CA8,BARD1,KIF26A,PHF1,EPDR1,TP73,CALM2,DAPK2,WEE1,ZYX,PQLC2,PSMD1,AP1M2,TGFBR3,RGS12,DNAH6,CABP1,CYP2S1,ALDH1A3,SLC46A1,RDH14,FUT1,TUBG1,ACOX2,PIK3CD,TINAGL1,APOBEC3G,ERAP2,TUBA4A,NWD1,SPEF2,VPS11,TNIP1,SH3BGRL,RNF11,MTRF1L,ICMT,PPP1R14C,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,SERPINB6,MRPS28,ARF6,PDPR,GAB1,ALDH6A1,NFKBIE,NUAK1,CYP2J2,STRN4,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,DNPEP,WDFY1,FAM13B,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,NAGPA,UFD1L,KIF20A,SALL4,STAT4,CALCRL,PLS1,SRSF5,ILK,MEST,TP53INP2,SPTLC2,RHOB,DCP2,CYB5A,DHX32,NAAA,NCOA3,SCARB2,MTFMT,TIMM8A,HTT,ITPR1,AURKA,DYSF,GSKIP,MDH1,ALG2,B4GAT1,MAL2,NDE1,DRP2,ARPC2,TRPC3,SERPINB1,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,PAPSS2,TMSB15A,TUBB4B,GALNT12,ETNK1,RGS20,WDTC1,TESK2,NUF2,PRKACA,APC2,KTN1,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,SCN3A,CAMSAP3,SSH3,PSRC1,LGALS8,NRBF2,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,PXYLP1,RAB38,IRS2,PEX5,STX10,SLC9A6,WWTR1,SIPA1L1,INPP4B,PDXK,RGS14,ARNT,TTC8,GALK1,FARP1,TNRC6C,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,PDIA3,PKN1,NUCB2,ETS1,GSTP1,ARHGEF40,SRPX2,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CAPN2,ANK1,ADD3,IRAK1,CTSC,ARSG,FAM160A2,ANKS1B,MCF2L,ALG13,CALD1,FDXR,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,MAPK11,AK3,SGCB,ITM2C,TPCN1,S100A6,TMX1,CRTAP,MOB4,AMOTL2,NUDT8,LCA5,FMN1,CTNNAL1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,PLEKHA7,BLVRA,NEURL1B,FAM109A,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,GALNT3,BTG1,KIAA0141,CCDC6,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,MYL9,UNKL,UNC93B1,TRIM2,AGRN,GNPDA1,CUL4B,EPHA4,SUDS3,MCCC1,NDC80,CDIPT,HDAC6,PDGFB,SDC1,PIGL,PCNA,SHC3,CNTRL,LMAN2L,DDHD2,ELF5,DUSP10,RGS5,PXMP4,TLN2,TRAM1,DDX59,NEB,S100A13,CCDC38,CD55,ING1,HN1L,CITED4,C12orf65,EZR,TNFAIP8L1,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,CDK1,VCP,RHEB,PLEKHB1,OPTN,IRX3,DPYSL3,PLCH1,MFAP3L,TBC1D17,MAP2,WIPI1,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,POMT1,GLCCI1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,PGAP1,SSX2IP,CORO1B,VASP,DAZAP1,GATA2,CMTR2,PAK2,EXOC8,MDFIC,TMEM8A,PLCB2,ALDH3A2,PSMA5,C9orf9,CYP26B1,CHSY3,MRPS33,WDR72,TESK1,PCBP3,SPATA13,KBTBD8,EIF2AK1,IFIT3,UNC45B,ZDHHC3,G2E3,SMN1,MAPKAPK2,EPN3,MOSPD3,DHDH,COQ10A,H1F0,ITGA7,CSF1,MFSD2A,ATP1B3,CTBP1,IFI6,NIPA1,RNF146,KCNAB3,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,DGKA,ERBB2,RASGRP3,FAM198B,LPIN3,CYP26A1,C1orf116,SDF4,PER2,CDK14,ATP6V0B,SRPX,PLCG2,N4BP3,SRR,GYS1,MINPP1,EGLN3,FAR1,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,EVA1A,TCEB2,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,PSMD3,ANXA9,RPL22,AIFM3,LTA4H,CNEP1R1,NDST3,POMGNT2,COPG1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,CD63,RUSC2,BLVRB,GNE,PSMD10,NKRF,CRABP2,DSE,MTRNR2L1,CCDC92,CEP97,MAGEE1,SLC35B4,BUB1,ABCD1,KLF9,HEXIM2,FAIM,CAMK2G,TLE6,FAH,HMMR,MLEC,PSMB4,IFITM3,NR3C1,AMFR,LITAF,CAPNS1,CARD19,TRIM35,FXR2,PELI3,AKAP3,FNDC3A,BCAR1,BORA,MAPK8IP1,PRDX4,FUCA1,TMEM50B,SERPINA1,NAT1,ZMYND19,CDCA7L,NMI,PGRMC1,PPP2R3C,PKD2,SPCS3,ACADM,NDFIP1,TBC1D4,UBE2C,SAT2,DIS3L,SUN1,GAA,CFAP74,PPP4R4,FAM129B,ATP8A1,KLC2,TAP1,PLXNA1,CCNB1,PLA2G16,FAM101B,RIC1,CENPN,NCS1,CHST2,CTGF,ELMO2,ZFP36,RGS3,STEAP2,AOX1,RCAN3,TFG,PACSIN1,LAMP2,KIFC2,SNTB2,CASP9,NBPF3,AGO4,TNS1,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,ULK2,SGPP1,AHRR,SFXN1,KDSR,SLC25A4,AREG,PLK2,GNPTAB,NKD1,FAM110C,SARAF,DHTKD1,EIF4EBP2,TMEM8B,TRAF5,RTN3,LZTS1,DLAT,DDX58,MRPL44,INPPL1,FRMD4A,HLA-E,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,NOTCH2,MECOM,ITGA3,SNX18,PIK3AP1,NECAB3,BDH1,CTPS1,SORL1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,FADS2,PMPCB,QSOX1,B3GNT7,MMD,B9D2,AMER1,PTPRH,PIP4K2C,KCTD20,VEZT,PKM,CYFIP2,KDM3A,FBXO10,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,SERTAD2,PRKAG2,CSNK1G1,DCK,FGD6,NR4A2,MAP3K5,NRBP1,IRF1,PLA2G4A,ELK4,SLC2A4,CEP70,ARMCX3,NLRX1,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,RNF182,SNN,AIFM2,NUDT12,MNS1,GNB2,SLC25A35,CYHR1,CDKN1B,TNPO2,DAB2IP,IFIT1,LGMN,PHKA2,TMBIM1,TBC1D10B,GPX4,MYO5B,SEC23A,TMEM43,CAPN6,DMTN,LYRM1,TEP1,COX11,SLC11A2,PRKCQ,C15orf39,AKR1E2,SP4,NIN,PRDM11,ZNF641,FYN,JAK1,PPP2R5A,STK26,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,MLKL,HS3ST3B1,B4GALT3,NR3C2,MRPS9,OTUD5,WASF3,NUDT6,ARHGEF3,ANKRD13D,ATP9A,ARL4C,CDCA3,APOBEC3H,SPR,SLC35G2,SIX4,RND1,SNTA1,FAM111A,OXCT1,PTEN,MGAT1,CENPJ,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,CNOT6L,MAP3K7,CNPY3,SPRY2,TRIM62,NCOA2,SMC4,PCCB,RASGRF1,ARAP2,SHMT1,CASK,ERMAP,DENND1B,MPP1,PARP4,VAMP3,FURIN,C1GALT1C1,LRRC1,GPLD1,NUCB1,RGS9,CTNS,PRDX3,SLC25A40,SERPINB5,PGM2L1,GPER1,ETAA1,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,USP16,EXPH5,EMX1,CASP3,ST13,CPT2,CAMKK1,HEBP1,UBE2Z,KIF2C,CACNB4,DNER,DENND2D,SH3KBP1,ABCD4,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,IMPAD1,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,ANKRD12,KIF22,RAB20,RP2,NFU1,MYH14,ARNT2,TECR,PTPRE,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,TRIM8,SYNE3,STRIP2,FOPNL,RNF165,ROR1,MRPS18A,MRPS36,PTGFRN,STK17B,TCN2,EDNRA,SEC14L2,MDK,CXXC4,NEIL1,FASTKD1,TRIM45,IARS2,APBA2,RAP1GAP,PSMC1,PPP2R5D,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,ELOVL7,ASL,ATP6V1E2,SAMD9,PHLPP1,CA2,FNIP1,KNTC1,ACAD8,NCEH1,ALS2CL,DESI2,KDELR1,OXR1,GYLTL1B,FBXO8,AMDHD1,EGFR,GLCE,GNAS,FECH,NUDT16,TSC1,PLPP3,PAPD5,NFKBIA,CDCA5,RHOBTB2,PITPNA,KIF12,FBXW5,PROM2,GAS2L1,SLC25A24,SPC25,IL15,SLC2A8,PSME2,GMPR,TDRKH,ZMYND10,PATL2,MICALL2,ARHGEF16,LRRC45,SLC25A48,SS18,ZDHHC12,FRYL,SMO,GOT1,STEAP3,RPN2,APIP,F2R,PDIA6,LOXL1,SCYL3,HSPA2,MAP3K3,GCA,BAG4,KREMEN2,OSTM1,AP5M1,ERBB2IP,SNAPC2,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,CANT1,CYP2U1,SGOL1,REEP4,PPP2R2D,ANXA3,CDS2,SORT1,JKAMP,FRMD6,POC1B,ARMC7,TRMT2B,POMGNT1,SAC3D1,IL17RB,SNX13,ADORA1,MLPH,GALNS,KIAA0319,TRIM3,BRD7,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,RAB3B,CENPC,ASPM,GCLC,NR4A1,MBNL3,OGDHL,POLD3,MPV17L2,SPAG1,MAP1B,KLHL2,HLA-B,MARC1,DHRS2,PRCP,HNRNPH2,UBE2D2,GLB1,ATP6V1C1,SOX8,SNPH |
| 1.030e-38 | -87.47 | cytoplasmic part | cellular component | GO:0044444 | 7817 | 1451 | 17570 | 2579 |
GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,TRAPPC8,TGOLN2,ISOC2,LACTB2,SNX9,CARD10,NPM2,CDKN2C,NAPG,MUC4,DNM2,PPP1CA,TIAM1,CPE,MGAT5,DSTN,UXT,CDA,TMEM98,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,LCP1,ABR,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,HSPB1,STARD13,ANXA11,SCN5A,GGA1,SEC61G,RAB23,GPSM2,COX6C,FAM21C,RABGGTA,ATG4A,MARCH8,RAC2,FRY,ATP5H,FLRT3,FBXO7,FBXL14,PCYOX1,CADPS2,MYDGF,MAPK7,MOXD1,NUP85,PHKG2,PPP6R1,MCCC2,HPS3,PQLC3,MAPKAPK3,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,PSMA4,GNA11,SFXN5,PLIN5,FNTA,APMAP,DGAT2,CFAP20,TMEM173,RUSC1,DOCK9,DMPK,NQO1,LFNG,INPP5D,APOO,PTTG1,MAPK4,MGST2,MVB12B,MOCS1,APPBP2,RCN1,MUC16,CDH1,XYLT2,TAX1BP3,RASGEF1A,SNX10,MX1,SNX8,SEC61B,ERMP1,COL6A2,RIPK2,APOBEC3D,AGPS,PFKFB2,SEPT6,SAT1,VPS4B,SYP,DNAJB14,SNX12,COX20,GABARAPL1,ALDH3B1,PDLIM3,CDK19,WFS1,PNPLA6,SLC25A30,ISOC1,MAPK12,MZT1,HSP90B1,GCAT,CKAP2,BACE1,TRAF2,BIK,SDC4,HABP4,FLOT1,CTSZ,SLC25A43,SGPL1,CTNNBIP1,SLC25A45,PDCD10,FUT2,GPC3,MGAT4A,FAM20B,CST3,TUBGCP6,BAX,IGFBP2,PARP9,ACBD5,OPLAH,PLSCR1,PIK3R1,DUSP23,MRS2,UBE2A,AK4,RAB3IP,LDLRAP1,PROM1,RPL12,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,FAM3C,PLA2G15,NR4A3,SSNA1,ITGAV,CMPK2,WDR45B,ACOT7,ILDR1,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,DNAJB11,F11R,ITPR2,MGAT5B,SPTB,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,P4HB,ARL1,PSMC2,PAPSS1,SLC44A1,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,KCNIP3,STAU2,NFE2L1,CCBL2,ARFRP1,SESN1,DZIP1L,TRIM9,HS6ST1,PI4K2B,AGPAT2,ARRDC1,KPNA2,MYL12B,RRAGD,LMTK3,USH1C,LGALS3,DNAJB2,FXYD3,RASA2,PSMD7,SORBS3,ADCK5,RAB6A,NCKAP1,RSAD1,B4GALNT1,TIMP1,RINL,SLC30A6,FCHO1,SELK,AHCY,FAR2,WNT3A,MPHOSPH9,CKAP4,DPYSL5,RGMB,MGAT4B,EMC2,STRADB,SCRIB,PDK3,BCL2L13,NMT2,CDK5R1,C18orf8,RASGRP2,FA2H,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,CCNB2,RAD21,TP53,RHPN2,STIL,EMP2,BCAP31,SYTL2,PDGFA,WDR44,PLK4,ZDHHC23,VAT1,NOTCH3,OAS3,TMEM64,LMAN1,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,ACO1,DAG1,ATP13A2,PTGS2,TAPBP,IDE,PAFAH1B3,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ARHGAP4,ST3GAL1,BTBD6,FAM134B,ARFGEF3,BIN1,CMAS,PINK1,CPEB4,TAB3,CTSB,SCD5,HAL,CDCA8,ERCC6L,LBR,AIP,PARM1,VPS26A,DNAJB9,FZD6,M6PR,ZDHHC21,CDK16,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,HMGCL,CPLX1,SYK,GCNT1,P2RX4,RHOA,GUSB,PLAUR,CRIP2,PRICKLE1,DPP9,STMN3,MAML2,GGH,COL7A1,RNPEP,BBS2,TXNDC11,BCL10,USP6,CNOT2,DDAH1,SCG2,NIPSNAP3A,PTGES,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,SLC35D2,TXN,HSPG2,TSC22D3,CUL1,PSME1,NANS,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,TYMP,CYP1A1,STIM1,OSBPL3,PALD1,KCNS3,PIK3CA,IRF2,SNX16,TACSTD2,MARCH2,METAP2,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,POR,RAB2B,BMP1,MAPK13,SPRY4,F2RL1,SLC31A2,FGD1,SCOC,DHPS,TBC1D1,TMEM55B,PRKAA1,HERC6,APBA1,PDXDC1,PSIP1,MESDC2,CALR,DOPEY2,ZNRF2,RPL39,VASN,TPST1,PRKG1,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,PRODH,GCC2,KLK5,CEP89,ADCK3,LPGAT1,CALM1,PYGL,NPC2,ATP8B3,ANTXR1,PDE11A,NT5C2,AP1AR,PLEKHH2,FAAH,PELI2,ZDHHC20,AGBL5,ARAP1,APPL2,KLK7,SAMD8,PLIN3,HOOK1,IFIH1,EHD1,KIF3C,GPR107,THRA,CERCAM,RALBP1,NDRG1,CCDC110,ATP2C2,FTH1,BCL2L1,FLT3,CYP39A1,ZFYVE9,EPM2A,CD46,CCNA2,ACAP2,RALB,PDE4D,EPHB4,OSBPL7,TSPAN1,SULT2B1,FLOT2,NAGA,SEMA3B,ATG4D,DOCK4,COG2,CYB5R2,PANK1,CLSTN1,KIF1C,PKMYT1,CBL,B3GALNT2,ITPR3,TRIQK,ATP10D,CEP162,ZMPSTE24,DDOST,ACAD10,NGFRAP1,SLC27A3,AREL1,COBL,MAMDC2,PRKAR1A,IGFBP6,CENPI,EPS8,HERC5,PLD2,FBXO6,SPDL1,DNAH3,HLA-A,COX7A2,SLC25A36,CKAP5,GOLGA2P5,RNF128,FUT8,DRAM1,CD9,TTPA,MSH6,FARP2,PDGFC,ZWINT,ARHGEF28,ALDH2,B3GNT2,DIAPH2,UBAC1,YES1,FOS,ARSK,KIF11,CPTP,DCTN6,ACADSB,FGFR2,RIN3,ERAP1,LRRK1,WDR62,FZD5,ESPL1,MELK,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MAP1LC3B,ERP29,SLC8B1,ECI1,TRIM68,ZFYVE16,RAB15,METTL7A,CASC4,CDKL5,SIVA1,CEP78,TRPC1,CTTN,MYRIP,BTBD3,LAMP3,CERS2,CYP1B1,NLRP4,CENPA,LAP3,ITCH,ACBD3,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,CAB39,SP6,GLA,CHPT1,NRGN,CAPN1,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,PPP1R12A,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,QSOX2,SPP1,B3GALNT1,NOXA1,CES2,FAM20C,PFKL,OCRL,COL6A1,SUCO,PRKCI,SRP54,NPTN,HLA-C,GAD1,CCDC88A,SNX7,ELK3,PDE5A,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,RHPN1,INSR,UAP1,TMEM30A,SH3BP4,RAB31,CTSA,SHROOM2,JAK3,APOL2,COL16A1,SNX30,DRD1,CCNE2,LZTFL1,DYNLRB1,SORBS1,SOD2,PDIA5,COL18A1,SAYSD1,PHLDA1,EXT2,CYP4F11,COX14,KIF14,REEP1,FABP6,DIXDC1,ECE1,NFKB2,ETHE1,UPF3A,EBAG9,CHP1,SOAT1,RFK,C3orf52,MRPS35,GLO1,TMTC2,CDC25C,CASP4,PDHX,ARHGAP35,SOCS3,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,SPTBN5,ABCA1,KDELC2,GLIS3,FBLIM1,GCLM,ENO2,ARHGEF11,SH3D19,CIT,ARHGEF7,SERPINB9,TGFBR1,COL4A5,XPR1,ITGA2B,TMEM63A,SYDE2,KIF5B,TOP2A,MZT2A,CARD8,ADRBK1,LLGL2,A4GALT,RRBP1,ZDHHC13,ACTA2,KANK2,CLIP2,RPGR,SLC35A1,MYO5A,B3GALT6,PGM1,CFAP46,SYBU,RC3H2,NADK2,CTSL,ARHGAP24,CASP7,SWAP70,RND3,CTSV,RAP2C,CSGALNACT1,DTX4,ARRB1,UACA,MCUR1,CEP41,PLOD3,AHR,ABCG1,NGEF,DOC2A,ACACB,KLK10,TRIM24,IL15RA,ADD1,TRIM5,AASS,MRPS15,DNAJC3,MMADHC,FBXO2,XIAP,IL18,LGI3,CNTROB,SYTL4,KIF26A,EPDR1,TP73,DAPK2,CALM2,AP1M2,PSMD1,PQLC2,DNAH6,CYP2S1,CABP1,ALDH1A3,RDH14,FUT1,TUBG1,ACOX2,PIK3CD,TINAGL1,APOBEC3G,ERAP2,TUBA4A,NWD1,VPS11,SPEF2,RNF11,MTRF1L,ICMT,MYOM1,CYP4F3,COL12A1,CAMK2N2,WDR11,DNM1L,LIMK1,MYLK,SERPINB6,MRPS28,ARF6,PDPR,GAB1,ALDH6A1,NFKBIE,CYP2J2,SLC36A4,LMNA,GNS,WDFY1,FAM13B,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,NAGPA,UFD1L,KIF20A,CALCRL,PLS1,ILK,MEST,TP53INP2,SPTLC2,RHOB,DCP2,CYB5A,DHX32,SCARB2,NAAA,MTFMT,HTT,TIMM8A,ITPR1,AURKA,DYSF,MDH1,ALG2,B4GAT1,MAL2,NDE1,ARPC2,TRPC3,RPS6KA3,EGLN1,XDH,ARHGAP11A,MTM1,CCDC109B,PAPSS2,TUBB4B,GALNT12,ETNK1,RGS20,WDTC1,NUF2,PRKACA,APC2,KTN1,CDS1,CCND1,SCNN1A,DACT1,ACSL4,RAB27B,CDKN2D,TMEM9,PSRC1,LGALS8,NRBF2,FZD4,CYS1,SYNE2,PXYLP1,RAB38,IRS2,PEX5,STX10,SLC9A6,WWTR1,INPP4B,PDXK,TTC8,GALK1,TAOK2,TNRC6C,FARP1,MAN1A2,PDIA3,PKN1,NUCB2,GSTP1,NEO1,PDIA4,CAPN2,ANK1,ADD3,IRAK1,CTSC,ARSG,FAM160A2,ALG13,MCF2L,CALD1,FDXR,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,MAPK11,AK3,ITM2C,TPCN1,S100A6,TMX1,CRTAP,MOB4,AMOTL2,LCA5,NUDT8,CTNNAL1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,BLVRA,FAM109A,NEURL1B,SKA1,CRISPLD2,ABLIM2,GALNT3,KIAA0141,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,MYL9,UNC93B1,AGRN,CUL4B,EPHA4,NDC80,MCCC1,CDIPT,HDAC6,PDGFB,PIGL,SDC1,SHC3,CNTRL,LMAN2L,DDHD2,DUSP10,PXMP4,TRAM1,S100A13,NEB,CD55,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,CDK1,VCP,RHEB,OPTN,DPYSL3,PLCH1,TBC1D17,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,CTNND1,PIK3C2B,TTC9,PIEZO1,POMT1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,PGAP1,SSX2IP,CORO1B,VASP,GATA2,PAK2,EXOC8,MDFIC,TMEM8A,PLCB2,ALDH3A2,PSMA5,C9orf9,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,KBTBD8,IFIT3,UNC45B,ZDHHC3,SMN1,DHDH,MOSPD3,EPN3,MAPKAPK2,COQ10A,H1F0,CSF1,MFSD2A,ATP1B3,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,P3H2,XYLT1,DGKA,ERBB2,RASGRP3,FAM198B,LPIN3,CYP26A1,SDF4,PER2,CDK14,ATP6V0B,SRPX,N4BP3,PLCG2,GYS1,EGLN3,MINPP1,FAR1,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,EVA1A,TCEB2,COQ10B,S100A4,CDC20,MYL12A,DNAJC10,ATP1A1,PSMD3,ANXA9,RPL22,LTA4H,AIFM3,NDST3,POMGNT2,COPG1,MAN2B2,COL9A3,GOLIM4,PACSIN2,TRAPPC10,MACC1,CD63,RUSC2,BLVRB,GNE,PSMD10,NKRF,CRABP2,DSE,CCDC92,CEP97,MAGEE1,SLC35B4,BUB1,ABCD1,CAMK2G,TLE6,FAH,MLEC,PSMB4,NR3C1,IFITM3,AMFR,LITAF,CAPNS1,CARD19,FXR2,PELI3,AKAP3,FNDC3A,BORA,BCAR1,MAPK8IP1,PRDX4,FUCA1,TMEM50B,SERPINA1,NAT1,PGRMC1,PKD2,ACADM,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,CFAP74,FAM129B,ATP8A1,KLC2,TAP1,CCNB1,PLA2G16,RIC1,CENPN,NCS1,CHST2,CTGF,ELMO2,ZFP36,RGS3,STEAP2,AOX1,PACSIN1,TFG,LAMP2,SNTB2,CASP9,AGO4,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SAV1,SLC25A5,ULK2,SGPP1,SFXN1,KDSR,SLC25A4,AREG,PLK2,GNPTAB,FAM110C,SARAF,DHTKD1,TMEM8B,TRAF5,RTN3,DLAT,DDX58,MRPL44,INPPL1,HLA-E,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,NDUFA4,ISYNA1,SLC1A3,NOTCH2,MECOM,ITGA3,SNX18,PIK3AP1,NECAB3,BDH1,CTPS1,SORL1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,FADS2,QSOX1,B3GNT7,PMPCB,MMD,B9D2,AMER1,PIP4K2C,VEZT,PKM,CYFIP2,GLT8D2,RASA1,STX3,FAS,DGKH,PRKAG2,DCK,FGD6,MAP3K5,NRBP1,IRF1,PLA2G4A,SLC2A4,CEP70,ARMCX3,NLRX1,TRIP10,RPS6KA1,IQGAP1,CAST,SNN,AIFM2,NUDT12,MNS1,GNB2,SLC25A35,CYHR1,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,TMBIM1,GPX4,MYO5B,SEC23A,TMEM43,CAPN6,DMTN,LYRM1,COX11,SLC11A2,PRKCQ,NIN,FYN,PPP2R5A,JAK1,STK26,STAT1,PPP1CB,SLC27A1,KLF5,RAB29,MLKL,HS3ST3B1,B4GALT3,NR3C2,MRPS9,OTUD5,NUDT6,ARHGEF3,ANKRD13D,ATP9A,CDCA3,APOBEC3H,SPR,SLC35G2,RND1,OXCT1,PTEN,MGAT1,CENPJ,PRC1,SGK3,ATP8B1,SLC44A2,MAP3K7,CNOT6L,CNPY3,SPRY2,TRIM62,SMC4,RASGRF1,PCCB,ARAP2,SHMT1,CASK,ERMAP,MPP1,DENND1B,VAMP3,FURIN,C1GALT1C1,GPLD1,NUCB1,CTNS,PRDX3,SLC25A40,PGM2L1,GPER1,ARSB,SLC25A38,OCLN,ESYT2,EXPH5,CASP3,ST13,CPT2,CAMKK1,KIF2C,CACNB4,DNER,SH3KBP1,ABCD4,CHPF,GRHL1,IMPAD1,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,KIF22,RAB20,RP2,MYH14,NFU1,TECR,FGFR1OP2,RASGRP1,ATL1,SOD1,TRIM8,SYNE3,FOPNL,MRPS18A,PTGFRN,MRPS36,STK17B,TCN2,EDNRA,SEC14L2,CXXC4,FASTKD1,IARS2,APBA2,RAP1GAP,PSMC1,PPP2R5D,STARD3NL,GRN,FAM213B,PIFO,PEX6,ELOVL7,ASL,ATP6V1E2,PHLPP1,CA2,KNTC1,ACAD8,NCEH1,KDELR1,OXR1,GYLTL1B,FBXO8,AMDHD1,EGFR,GLCE,FECH,GNAS,TSC1,PLPP3,NFKBIA,CDCA5,RHOBTB2,PROM2,SLC25A24,SPC25,IL15,SLC2A8,PSME2,GMPR,TDRKH,ZMYND10,PATL2,MICALL2,ARHGEF16,SLC25A48,SS18,FRYL,ZDHHC12,SMO,STEAP3,RPN2,GOT1,PDIA6,LOXL1,F2R,SCYL3,HSPA2,MAP3K3,BAG4,KREMEN2,OSTM1,AP5M1,BFSP1,PEX2,CANT1,CYP2U1,SGOL1,REEP4,ANXA3,CDS2,SORT1,POC1B,JKAMP,TRMT2B,POMGNT1,SNX13,ADORA1,MLPH,GALNS,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,RAB3B,CENPC,GCLC,OGDHL,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,MARC1,DHRS2,PRCP,UBE2D2,GLB1,ATP6V1C1,SNPH |
| 7.495e-35 | -78.58 | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | MSigDB lists | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | 837 | 258 | 17758 | 2588 |
FAM171B,VANGL1,DNAJC3,RET,XIAP,CCNO,C1orf198,FAM101B,BARD1,CA8,CMTM6,EPDR1,PAK6,ZNF823,KCNS3,ATRNL1,HYLS1,MANF,PPP1CA,RNF26,SMARCA2,SERTAD4,PIF1,SGPP1,PRIM1,ANKRD6,LRIG1,FAM110C,NOD2,NFKBIZ,SPRY4,RNASEL,LSM14B,E2F8,RECQL,TMTC3,RAB23,KIF23,GPSM2,BMP2K,PRRG4,ATG4A,SLC16A6,ZIC5,USP1,CADPS2,ZMYM1,MFI2,KIAA1841,KIF20A,PRSS23,ANO6,WHSC1,KIF20B,NPHP3,NFIB,IL1R1,NCOA3,SEMA4D,FAM83D,ZBTB34,NDE1,ARHGAP11A,DLGAP5,IQGAP1,GALNT12,C5orf30,IRX4,KCTD12,NUF2,TMEM170B,MNS1,ZNF385B,KIAA1147,EPM2A,RTKN2,LGMN,CDKN2D,SNX10,ENPP4,TMEM200B,PSRC1,ERMP1,FZD4,CLSTN1,ALCAM,SP4,FZD7,NIN,ZNF641,PDLIM3,ZNF704,PPP1CB,HS3ST3B1,GEN1,SLC25A30,PRKAR1A,NKX3-1,MZT1,MPZL1,FAM189A2,DEPDC1,SLC16A14,CENPI,EPS8,ARL4C,GPR180,NUCB2,SIX4,CTNNBIP1,RASSF8,IRAK1,FAM20B,ZNF230,NPTXR,SGCB,TTPA,MED22,MSH6,SMC4,HCN3,PAPD7,TCFL5,CXorf57,SKA1,FOS,ACADSB,RCBTB2,RAB11FIP2,ZFP30,SLC25A40,AMMECR1,CENPE,ITGAV,CMPK2,FOXA1,UGT8,FAM199X,ARFGEF1,FHDC1,MPP5,MAP1LC3B,TRIM68,FANCI,PLS3,NPNT,GRHL1,IL6ST,PASK,CEP78,PHTF1,TRPC1,PTPRE,IL1RAP,PCGF5,TDP1,CENPA,USP18,CKAP2L,C12orf65,EAF2,ANLN,ADRBK2,STK17B,KDM4D,MAN2A2,TMEM164,KCNMB4,CDCA4,ZNF114,ZNF165,CHPT1,GLCCI1,RAP1GAP,PRKAA2,HJURP,PPP1R12A,LRRFIP2,UBASH3B,RACGAP1,B3GALNT1,RB1,OTUD1,IGF1R,SPIN4,LIMCH1,PIM1,NCEH1,CKAP4,CHSY3,BTNL9,ZNF320,SPATA13,TCF7,PRRC1,BCL2L13,G2E3,GNAS,TMEM30A,PRPS2,PAPD5,SH3BP4,NIPA1,RAD21,IL15,SLC7A2,STIL,KBTBD11,CDK14,SS18,KCTD15,KIF14,REEP1,ZDHHC23,PLK4,LMAN1,HSPA2,CTH,SOAT1,SIRT1,SLC39A8,CDC20,TMTC2,ALDH5A1,OVOL1,ZBTB6,ZNF701,PPP2R2D,KDELC2,CIT,ERCC6L,NKRF,RBP7,DNAJB9,KIF5B,IL17RB,SNX13,LYPD6,SLC35B4,FAIM,HMMR,RAB3B,ASPM,MBNL3,PRICKLE1,BORA,CD83,ENDOD1,CASP7,NEIL3,NMI,UBE2D2,OTUB2,UACA,CLIP4,SPCS3,ZBTB33,DIS3L |
| 1.097e-33 | -75.89 | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | 530 | 187 | 17758 | 2588 |
FAM171B,BCAM,ACVR1,EPAS1,FAM160B1,CRYM,ATP8A1,TMEM41B,PPFIBP2,NANS,SLC20A1,SDC1,BTG3,ANKS6,ARHGEF37,IQCE,ZFP36,ELF5,ALDH1A3,KLF3,RAB20,TACSTD2,PACSIN1,TLN2,SCARA3,TRAM1,OLFML2A,KRT80,CD55,MARK1,SH3BGRL,EZR,KDELR3,PTGFRN,IDH1,LHFPL2,ARF4,MFAP3L,PI4K2B,TRAM2,KLF12,WIPI1,MYLK,FAM114A1,CAB39,CTNND1,TMEM8B,TTC9,EPB41L4A,TRAF5,GLCCI1,GAB1,HOXC13,ARAP3,NUAK1,TMTC3,CYP2J2,FXYD3,NCKAP1,DOCK11,DHRS3,PDXDC1,TNS3,GATA2,FAM20C,LYPD3,KCNN4,VASN,LIMCH1,CADPS2,NCEH1,SLC12A2,ULBP2,FAM69A,IGSF3,GFPT1,PRODH,SLC37A1,TBC1D8B,PIP4K2C,SPATA13,TP53INP2,PCTP,MUM1L1,FAS,FECH,EPN3,IL1R1,NT5C2,PAPD5,SH3BP4,FGD6,PLD1,PROM2,CAST,GALNT12,ATP2C2,ERBB2,IL13RA1,FAM198B,OSR2,DDR1,IER3,CDS1,CD46,FAM46A,TACC2,BCL6,CDH3,PDE4D,EPB41L4B,RASGEF1A,TSPAN1,RAB27B,LOXL1,SCYL3,CPD,CLCN3,TIMP2,FZD4,SAT1,UTRN,SLC11A2,DOCK5,ALCAM,DAG1,NFIX,ARHGAP35,PTPRJ,CCDC149,SLC9A6,ZNF704,INPP4B,CANT1,VSIG10,FAM149A,PDXK,ABCA1,KDELC2,GSDMD,ANXA3,MACC1,JKAMP,PBX3,CYB561,FBXO6,NUCB2,BEX2,HOXB2,SH2D4A,PARM1,RND1,SGPL1,IRF2BPL,SNX13,TMEM87B,OXCT1,MGAT4A,DRAM1,SLC44A2,TRIM62,CAMK2G,ATP2B1,PVRL4,PDGFC,ARAP2,TACC1,RAPGEF2,LITAF,PLEKHA7,DIAPH2,LRRC1,SPAG1,FUCA1,PITX2,GALNT3,TMEM50B,SWAP70,CASP7,TWSG1,SYT7,RND3,FIBCD1,TADA2B,ARRB1,GRIN2D,PKIA |
| 9.731e-33 | -73.71 | ONDER_CDH1_TARGETS_2_DN | MSigDB lists | ONDER_CDH1_TARGETS_2_DN | 445 | 165 | 17758 | 2588 |
EXPH5,KLK10,AGRN,IL15RA,LGR4,EPAS1,MCOLN3,IL18,F11R,SDC1,NUP62CL,EPCAM,PAK6,CYP1A1,AP1M2,ALDH1A3,DUSP10,CLDN4,TACSTD2,TINAGL1,PTPRE,IL1RAP,CD55,MARK1,CELSR2,ARHGDIB,RBM47,HPSE,AREG,KCNK1,PLK2,ZNF165,MAPK13,SLC31A2,DDX58,PRSS8,PARP12,FAM169A,ITGA6,FXYD3,SOX9,ABCG2,CNTNAP2,SLC1A3,B4GALT4,HERC6,S100A2,ANO1,PRRG4,MYO5C,MECOM,BMP2,CA2,LYPD3,FLRT3,RIMS3,KCNN4,BHLHE41,AIM1,MAP3K9,TMEM51,SORL1,MAST4,ALS2CL,RIMS2,IGSF3,FAM69A,KLK5,CORO2A,PIP4K2C,EPHA1,STEAP1,CDK5R1,FRMD4B,PTPRF,EPN3,FGD6,KLK7,EFNA1,SERPINB1,IFIH1,HOOK1,SEMA3A,XDH,PLA2G4A,GRHL2,ST14,RPS6KA1,CD82,NDRG1,IRX4,MGST2,DDR1,TMPRSS4,C1orf116,EPS8L2,IER3,CDS1,SCNN1A,ARTN,CDH1,CYP4F11,CDH3,OAS3,EPB41L4B,TSPAN1,SNX10,GM2A,SEMA3B,MBP,ERMP1,KIAA0040,CYB5R2,SLC39A8,RAB38,DUOX1,PTGS2,POPDC3,INPP4B,MAOA,KLF5,NRG1,SLC27A3,ANXA3,ARHGEF3,ESRP1,GNAL,MCTP2,SDC4,BIK,ARL4C,CYB561,JAG2,ICAM1,SIRPA,HDAC9,RNF128,CTSC,CD9,ZDHHC13,TSPAN13,ERBB3,SYK,NFE2L3,HES1,ARAP2,GCLC,SYBU,LRRC1,FOS,SPAG1,CD83,GALNT3,TIMP3,SERPINA1,FGFR2,SPINT2,CLIP4,SPCS3,FZD5,TBC1D4,PTGES,L1CAM,OCLN,ARHGEF4 |
| 2.254e-31 | -70.57 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | 665 | 213 | 17758 | 2588 |
ILDR1,SLC35D2,LGR4,EPAS1,FAM199X,CRYM,DNAJC3,PPFIBP2,TGOLN2,NANS,OAT,MAP1LC3B,PAK6,BTG3,ANKS6,ENTPD4,LRRC6,CTGF,ALDH1A3,SLC44A1,ELF5,RDH14,STEAP2,KCNS3,NTN4,NFU1,PTPRE,TRAM1,CYP1B1,PCGF5,CD55,ACVR1C,ACBD3,EAF2,GALNT7,PTGFRN,IDH1,STK17B,POR,SLC44A3,WIPI1,GDE1,ATP7B,FAM114A1,FAM110C,AGFG2,EIF4EBP2,TC2N,SCOC,SLC25A27,ASAH1,B4GALT4,DOCK11,TNFRSF19,CCDC64B,PDXDC1,LYSMD4,ATG4A,GNS,WDFY1,FRY,PIK3AP1,SNX18,BDH1,TPST1,LIMCH1,STT3B,NCEH1,ACAD8,SLC12A2,SNX7,GFPT1,QSOX1,B3GNT7,GCC2,WDR72,HPS3,SLC37A1,CORO2A,PTPRH,ZNF320,PDE5A,PCTP,STEAP1,C18orf8,PLIN5,CYB5A,FRMD4B,IL1R1,GNAS,EPN3,SLCO4A1,PLEKHH2,UAP1,PELI2,APPL2,PIAS2,FGD6,CLMN,PITPNA,NR4A2,STK39,PLD1,MAL2,SERPINB1,NIPA1,DOCK9,GPR107,UGP2,FAM92A1,ST14,GALNT12,CAST,RPS6KA1,ATP2C2,APOO,ETNK1,CCDC68,FTH1,IL13RA1,AIFM2,EPS8L2,C1orf116,CDS1,CD46,NOV,ATP6V0B,SCNN1A,TACC2,EPB41L4B,TSPAN1,LRP11,PDIA6,NR2C1,SCYL3,MYO5B,CPD,SOAT1,TMTC1,ERLEC1,ERMP1,RFK,NRBF2,PFKFB2,SEPT6,SAT1,SLC11A2,ATP1B1,DUSP4,TMTC2,ZMPSTE24,OSBPL2,PTPRJ,POPDC3,SECTM1,EFNA5,ST3GAL1,PRR15,BIN1,NKX3-1,CPEB4,CD63,SLC16A14,DAP,GNE,GDF15,FBXO6,HOXB2,LBR,SH2D4A,TMEM63A,CAPN2,ADD3,GNB5,RRBP1,DRAM1,UBE2J1,H2AFY,TMBIM6,ATP8B1,C2orf72,AK3,CITED2,ITM2C,TPCN1,S100A6,PGM1,PHF20L1,LONRF3,CTNNAL1,PPARA,PLEKHA7,SNTB1,SPAG1,KLHL2,GALNT3,FUCA1,BTG1,CASP7,FAM3C,TMC5,DBI,DTX4,PGRMC1,ARFGAP3,OTUB2,SH3BGRL2,ACADM,ETAA1,FZD5,AHR,DCBLD1,GOLGB1 |
| 4.120e-29 | -65.36 | pleura-mesothelioma | COSMIC cancer mutations | pleura-mesothelioma | 4290 | 855 | 17775 | 2585 |
KLK10,TRIM24,AK7,TRIM5,DNAJC3,RET,SMARCAL1,XIAP,FBXO2,MMADHC,DHX8,MORF4L2,SYTL4,LACTB2,SNX9,BARD1,SPSB1,CARD10,PHF1,ZNF275,CDKN2C,TP73,DAPK2,WEE1,RGS12,PPP1R16A,ALDH1A3,KLF3,FUT1,PPP1CA,PIK3CD,RNF26,WBP4,TIAM1,APOBEC3G,NEK4,SMARCA2,FBXL16,SH3BGRL,UXT,RNF11,PRKAR2B,LOXL2,PPP1R14C,ICMT,ARF4,LCP1,PIAS3,PLCG1,TRIM47,MID1IP1,WDR11,LIMK1,MYLK,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RAC2,WDFY1,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,USP1,USP38,ALPK1,MAPK7,DGKG,NUP85,PHKG2,UFD1L,STAT4,MYBL2,SRSF5,ELK1,TP53INP2,GNA11,RHOB,STK17A,DHX32,PTPRF,MAGED2,NCOA3,ETS2,TIMM8A,ITPR1,DGAT2,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,CBX5,RPS6KA3,ADAMTS16,EGLN1,DMPK,ARHGAP11A,MTM1,TMSB15A,LFNG,CD82,PTTG1,APOO,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,KTN1,TNFSF9,APPBP2,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,SNX8,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,SYP,RAB38,DNAJB14,SNX12,TRIM7,NFIX,IRS2,SPIN3,CCNB3,CDK19,CORO1C,SLC9A6,AXL,INPP4B,PDXK,RGS14,GEN1,ARNT,MAPK12,FARP1,TAOK2,TRAF2,BIK,CTSZ,ANO9,PKN1,ETS1,IFT27,SLC25A43,ARHGEF40,TSPAN17,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,CXCL16,ANK1,PDCD10,ITGB8,IRAK1,KNDC1,KCNK5,GPC3,CALD1,ALG13,MCF2L,FDXR,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,RAG1,ADAMTS2,CTNNAL1,BCL9,RAPGEF2,DUSP23,PIK3R1,NUB1,CXorf57,PLEKHA7,UBE2A,AK4,RAB3IP,SNTB1,TXK,PITX2,BTG1,PROM1,CCDC6,NR1D2,ACVRL1,FAM3C,PPM1H,FBXO44,CENPE,ITGAV,HMGA1,FHL1,NUP37,CD81,SRSF9,FOXA1,TNK1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,NUP62CL,PIGL,PLS3,BTG3,INPP5E,RPS6KA2,PCNA,NUP210,CTNNB1,SHC3,CNTRL,ARL1,IL6ST,ELF5,DUSP10,RGS5,TNFRSF18,SCARA3,MYBL1,TRAM1,PLK1,THRB,KRT80,PCGF5,PTPN18,MARK1,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,RHEB,PLEKHB1,VCP,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,HOXA9,CTNND1,KLF11,KPNA2,PIK3C2B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,DNAJB2,RASA2,RACGAP1,ADCK5,RAB6A,HES2,RB1,IGF1R,TIMP1,SPIN4,GATA2,PIM1,PLCB2,ALDH3A2,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,BCL2L13,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,RAD21,USP43,NF2,UPF3B,FOXM1,DGKA,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PCBP1,STIL,BCAP31,RAD23A,CDK14,SRPX,WDR44,TACC2,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,RPL22,ARHGAP4,CMTM4,ZMAT1,BIN1,PINK1,DYRK3,GOLIM4,TAB3,KLHL13,GNAL,PSMD10,GDF15,NKRF,HMGN3,JAG2,LBR,PPP2R3A,SIRPA,DNAJB9,FZD6,ZDHHC21,FOXP2,CDK16,MAGEE1,UBE2J1,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,CAMK2G,DUSP1,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,HMGN5,CRIP2,LITAF,MAML2,TRIM35,AKAP3,BCAR1,DGKE,PRDX4,USP6,BCL10,DDX23,CNOT2,SERPINA1,NEIL3,E2F1,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,ACVR1,VANGL1,TSC22D3,PPFIBP2,GATA3,CUL1,CAMK1D,CCNB1,PICK1,SLC9A7,PAK6,ZFP36,RGS3,OSBPL3,PRICKLE3,IQCE,FOSB,POLL,SNX16,TFG,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,BNIP3L,AURKB,PIF1,SAV1,CCNF,SLC25A5,TP53I3,RAB2B,ULK2,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,SH2D3C,PPP2R4,LRIG1,NKD1,MAPK13,SERPINI1,SPRY4,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,DGKQ,PRKAA1,KIF23,AKAP17A,NOTCH2,S100A2,TNFRSF19,TSPAN7,PSIP1,BMP2K,MECOM,RALGPS2,ITGA3,SNX18,BHLHE41,RPL39,PPP4R1,MSH2,DAPK1,ADCK2,PRKG1,CD70,TNFRSF12A,PIKFYVE,RIMS2,EEF1D,SOCS5,PIGC,DDB2,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,WHSC1,KDM3A,FBXO10,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,TCEAL4,PIAS2,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,IRF1,FRMPD3,ELK4,PLA2G4A,SPRED1,REPS2,ARMCX3,TRIP10,NDRG1,SUZ12,RPS6KA1,IRX4,BCL2L1,CD274,FLT3,DDR1,GNB2,ZFYVE9,EPM2A,APOBEC3B,NOV,CCNA2,ZNF75D,RALB,DOK4,CDKN1B,TNPO2,PDE4D,EPHB4,PHKA2,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,BCL7B,CBL,ASB13,ITPR3,FZD7,ZMPSTE24,CMTM7,NIN,EPHA10,FYN,PPP2R5A,JAK1,NGFRAP1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,MLKL,ZC3H12B,CBX7,PRKAR1A,OTUD5,IER5L,ARHGEF3,CENPI,ARL4C,CBLL1,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,HLA-A,SCML1,RND1,WWP2,E2F7,RNF128,GNB5,PTEN,DRAM1,SGK3,ERCC2,ERBB3,MAP3K7,SPRY2,TRIM62,NCOA2,MSH6,SMC4,RASGRF1,TGIF1,ZWINT,ALDH2,CASK,LONRF3,MPP1,FURIN,C1GALT1C1,DIAPH2,FBXO9,YES1,FOS,KIF11,GPLD1,CRTC2,CDK5RAP1,TIMP3,RCBTB2,FGFR2,AMMECR1,CSTF2,SERPINB5,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,PLAC1,KIF2C,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,CDKL5,ZCCHC12,TSPAN6,CAPG,POF1B,ASH2L,RAB20,RP2,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TRIM8,CENPA,ASXL1,USP18,ACBD3,ITCH,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,GLA,RAP1GAP,PPP2R5D,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,PPP1R12A,ETV5,ASB9,DUSP5,SPP1,PFKL,OCRL,PRKCI,SRP54,BRAT1,KNTC1,ZRANB1,ETV7,SNX7,ELK3,FBXO8,RNF113A,PDIK1L,RANBP9,EGFR,MUM1L1,BCAR3,XKRX,INSR,UAP1,NFKBIA,PAPD5,RAB31,ALPK3,RHOBTB2,PITPNA,SHROOM2,JAK3,TOB1,RARG,FBXW5,CCNE2,PAX6,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,MXD1,SS18,SMO,TWIST1,APIP,LOXL1,HSPA2,SCYL3,EBAG9,CKS2,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,CDC25C,FANCE,KCTD2,PDHX,MAP3K6,CASP4,SOCS3,BHLHB9,STAT6,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,ARHGEF7,SERPINB9,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,ITGA2B,HDAC9,IL17RB,TOP2A,SNX13,CARD8,ADRBK1,LLGL2,MYCL,TRIM3,CKS1B,MXD3,HSPA13,RPGR,PGM1,ADAM17,RAB3B,WNT10B,SYBU,MBNL3,RUNX3,POLD3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,CASP7,RND3,HNRNPH2,RAP2C,UBE2D2,ZMIZ1,GEM,L1CAM,AHR,RAB3IL1,NGEF |
| 5.265e-29 | -65.11 | lung-carcinoma | COSMIC cancer mutations | lung-carcinoma | 4361 | 866 | 17775 | 2585 |
KLK10,TRIM24,AK7,TRIM5,DNAJC3,RET,XIAP,FBXO2,MMADHC,SMARCAL1,DHX8,LACTB2,SYTL4,MORF4L2,SNX9,BARD1,SPSB1,CARD10,PHF1,ZNF275,TP73,CDKN2C,DAPK2,WEE1,RGS12,PPP1R16A,ALDH1A3,KLF3,FUT1,PIK3CD,PPP1CA,WBP4,RNF26,TIAM1,APOBEC3G,NEK4,SMARCA2,FBXL16,SH3BGRL,UXT,RNF11,PRKAR2B,LOXL2,F12,ICMT,PPP1R14C,ARF4,LCP1,PIAS3,PLCG1,TRIM47,MID1IP1,WDR11,LIMK1,TRAF3IP1,MYLK,MAP3K11,NOD2,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ATG4A,ELF3,RAC2,WDFY1,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,USP38,USP1,ALPK1,MAPK7,DGKG,PHKG2,NUP85,UFD1L,STAT4,MYBL2,SRSF5,ELK1,TP53INP2,GNA11,RHOB,STK17A,DHX32,PTPRF,MAGED2,NCOA3,ETS2,TIMM8A,ITPR1,DGAT2,AURKA,MDH1,GDF11,DRP2,FBXO27,NDE1,CBX5,SERPINB1,RPS6KA3,DMPK,ADAMTS16,EGLN1,ARHGAP11A,MTM1,TMSB15A,LFNG,CD82,PTTG1,APOO,RGS20,TESK2,IL13RA1,NUF2,GRK6,PRKACA,APC2,TNFSF9,KTN1,APPBP2,CCND1,ST5,RNF220,CDH1,DACT1,ACSL4,ARL4D,DLG3,RASGEF1A,RAB27B,CDKN2D,ETV4,SNX10,SNX8,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,SYP,RAB38,DNAJB14,SNX12,TRIM7,NFIX,IRS2,SPIN3,CCNB3,CDK19,SLC9A6,CORO1C,AXL,INPP4B,PDXK,RGS14,GEN1,ARNT,MAPK12,TAOK2,FARP1,TRAF2,BIK,CTSZ,ANO9,PKN1,SLC25A43,ARHGEF40,ETS1,IFT27,TSPAN17,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,CXCL16,ANK1,PDCD10,IRAK1,ITGB8,CALD1,KNDC1,MCF2L,ALG13,KCNK5,GPC3,FDXR,BAX,PLEKHF1,ADAM15,WWP1,NKAPP1,MAPK11,RAG1,ADAMTS2,CTNNAL1,BCL9,RAPGEF2,PIK3R1,DUSP23,NUB1,UBE2A,CXorf57,PLEKHA7,AK4,RAB3IP,SNTB1,TXK,PITX2,BTG1,PROM1,ACVRL1,CCDC6,NR1D2,FAM3C,PPM1H,FBXO44,CENPE,HMGA1,ITGAV,FHL1,NUP37,CD81,FOXA1,SRSF9,TNK1,TRIM2,EPAS1,FAM199X,CUL4B,EPHA4,NDC80,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,NUP62CL,PIGL,PLS3,BTG3,INPP5E,RPS6KA2,PCNA,NUP210,CTNNB1,SHC3,CNTRL,IL6ST,ARL1,ELF5,DUSP10,TNFRSF18,RGS5,SCARA3,MYBL1,TRAM1,PLK1,KRT80,THRB,PCGF5,MARK1,PTPN18,CBX6,CR2,ARFRP1,KLK6,IDH1,SESN1,TRUB1,VCP,PLEKHB1,RHEB,KDM4D,TRIM9,TMEM164,PI4K2B,PLEKHG6,KCNMB4,HOXA9,CTNND1,KPNA2,KLF11,PIK3C2B,MAFF,RRAGD,HS6ST3,PRKAA2,RUNX2,BMF,RASA2,DNAJB2,RACGAP1,ADCK5,HES2,RAB6A,TIMP1,IGF1R,GATA2,SPIN4,PIM1,PLCB2,ALDH3A2,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,BCL2L13,G2E3,CDK5R1,FOXD2,RASGRP2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,USP43,RAD21,UPF3B,NF2,FOXM1,TP53,DGKA,P2RX7,ERBB2,RASGRP3,CCNL1,STIL,PCBP1,BCAP31,RAD23A,CDK14,SRPX,WDR44,TACC2,LMO4,PLCG2,PLK4,BCL6,NOTCH3,EGLN3,MINPP1,DVL2,SULF2,SIRT1,AKT1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,ARHGAP4,RPL22,CMTM4,BIN1,ZMAT1,PINK1,GOLIM4,DYRK3,TAB3,KLHL13,GNAL,PSMD10,HMGN3,NKRF,GDF15,JAG2,LBR,FZD6,PPP2R3A,DNAJB9,SIRPA,ZDHHC21,FOXP2,CDK16,MAGEE1,UBE2J1,SGK1,TRIM21,BUB1,ALDH7A1,ABCD1,FAIM,SYK,CAMK2G,DUSP1,WBP5,DLGAP1,HES1,RHOA,FBLN5,HMGN5,MOSPD2,CRIP2,LITAF,TRIM35,MAML2,AKAP3,BCAR1,DGKE,DDX23,PRDX4,BCL10,USP6,CNOT2,SERPINA1,NEIL3,PGRMC1,E2F1,SH3BGRL2,PPP2R3C,UBE2C,ARHGEF9,PTGES,HIPK3,ZBTB33,ARHGEF4,ACVR1,VANGL1,TSC22D3,PPFIBP2,CUL1,GATA3,CAMK1D,CCNB1,SLC9A7,PICK1,PAK6,RGS3,IQCE,PRICKLE3,ZFP36,OSBPL3,FOSB,POLL,PIK3CA,SNX16,TFG,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,HSPA12A,CASP9,BNIP3L,AURKB,PIF1,CCNF,SAV1,SLC25A5,TP53I3,ULK2,RAB2B,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,SH2D3C,NKD1,PPP2R4,LRIG1,MAPK13,SERPINI1,SPRY4,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,DGKQ,PRKAA1,KIF23,AKAP17A,NOTCH2,TNFRSF19,S100A2,PSIP1,TSPAN7,BMP2K,MECOM,CALR,ITGA3,RALGPS2,SNX18,RPL39,BHLHE41,PPP4R1,ADCK2,PRKG1,DAPK1,MSH2,TNFRSF12A,CD70,PIKFYVE,EEF1D,RIMS2,SOCS5,PIGC,PRODH,PMPCB,DDB2,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,WHSC1,KDM3A,NFIB,FBXO10,RASA1,PDE11A,FAS,DGKH,MMP15,PRKAG2,TMEM54,TCEAL4,PIAS2,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,IRF1,ELK4,PLA2G4A,FRMPD3,SPRED1,REPS2,ARMCX3,TRIP10,SUZ12,RPS6KA1,NDRG1,IRX4,BCL2L1,CD274,DDR1,FLT3,GNB2,EPM2A,ZFYVE9,APOBEC3B,NOV,ZNF75D,CCNA2,RALB,DOK4,TNPO2,CDKN1B,EPHB4,PDE4D,PHKA2,CAPN6,FOXJ2,PRKCQ,BCL7B,PKMYT1,PYGO1,ITPR3,ASB13,CBL,FZD7,NIN,ZMPSTE24,CMTM7,EPHA10,FYN,JAK1,PPP2R5A,ACYP1,NGFRAP1,KIAA1804,STAT1,PPP1CB,SLC27A1,ZC3H12B,MLKL,CBX7,PRKAR1A,OTUD5,IER5L,ARHGEF3,CENPI,ARL4C,NES,CBLL1,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,SCML1,RND1,WWP2,E2F7,GNB5,RNF128,PTEN,SGK3,DRAM1,ERBB3,ERCC2,MAP3K7,SPRY2,TRIM62,NCOA2,MSH6,SMC4,RASGRF1,TGIF1,CASK,ALDH2,ZWINT,LONRF3,MPP1,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,FOS,KIF11,GPLD1,CRTC2,CDK5RAP1,TIMP3,RCBTB2,FGFR2,AMMECR1,ABCB1,CSTF2,SERPINB5,FZD5,NCAPG2,ESPL1,MELK,CXorf56,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,PLAC1,KIF2C,DENND2D,KREMEN1,SH3KBP1,ABCD4,ARHGEF10L,RAB15,CDKL5,ZCCHC12,TSPAN6,CAPG,POF1B,RAB20,ASH2L,RP2,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TRIM8,CENPA,USP18,ACBD3,ITCH,RGAG1,ROR1,ADRBK2,STK17B,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,GLA,RAP1GAP,PPP2R5D,CPPED1,NR2C2,CD99,ARAP3,PPP1R2,SERPINE2,PPP1R12A,ETV5,ASB9,DUSP5,SPP1,PFKL,OCRL,PRKCI,SRP54,BRAT1,KNTC1,ZRANB1,ETV7,SNX7,ELK3,FBXO8,RNF113A,PDIK1L,RANBP9,EGFR,MUM1L1,XKRX,BCAR3,INSR,UAP1,NFKBIA,PAPD5,RAB31,ALPK3,RHOBTB2,PITPNA,SHROOM2,JAK3,TOB1,RARG,FBXW5,CCNE2,PAX6,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,MXD1,SS18,TWIST1,APIP,LOXL1,HSPA2,SCYL3,CKS2,EBAG9,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,FANCE,CDC25C,KCTD2,PDHX,CASP4,MAP3K6,SOCS3,BHLHB9,STAT6,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,FRMD6,ARHGEF7,SERPINB9,TGFBR1,COL4A5,TRMT2B,TRIB2,ITGA2B,HMGXB4,HDAC9,KIF5B,TOP2A,IL17RB,SNX13,CARD8,ADRBK1,LLGL2,MYCL,CKS1B,TRIM3,MXD3,HSPA13,RPGR,PGM1,DCAF6,RAB3B,ADAM17,WNT10B,SYBU,MBNL3,RUNX3,TCEAL8,POLD3,FOXL1,ARHGAP24,KLHL2,CASP7,SWAP70,RND3,HNRNPH2,RAP2C,UBE2D2,GEM,ZMIZ1,L1CAM,AHR,RAB3IL1,NGEF |
| 1.081e-28 | -64.39 | kidney-carcinoma-renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-renal_cell_carcinoma | 4650 | 911 | 17775 | 2585 |
KLK10,TRIM24,GRIK2,AASS,AK7,TRIM5,DNAJC3,RET,MCOLN3,SMARCAL1,XIAP,MMADHC,FBXO2,DHX8,MORF4L2,SYTL4,LACTB2,SNX9,BARD1,SPSB1,CARD10,PHF1,ZNF275,GRM5,CDKN2C,TP73,DAPK2,WEE1,RGS12,PPP1R16A,ALDH1A3,KLF3,FUT1,PPP1CA,TINAGL1,PIK3CD,RNF26,WBP4,TIAM1,APOBEC3G,NEK4,SMARCA2,FBXL16,SH3BGRL,UXT,RNF11,PRKAR2B,LOXL2,PPP1R14C,ICMT,ARF4,LCP1,PIAS3,PLCG1,TRIM47,MID1IP1,WDR11,LIMK1,MYLK,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,ZNRF3,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RAC2,WDFY1,RIMS3,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,USP1,USP38,ALPK1,MAPK7,ZMYM1,DGKG,KANK3,NUP85,PHKG2,UFD1L,STAT4,MYBL2,SRSF5,ELK1,TP53INP2,GNA11,RHOB,STK17A,DHX32,PTPRF,MAGED2,NCOA3,ETS2,HTT,TIMM8A,ITPR1,DGAT2,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,CBX5,RPS6KA3,ADAMTS16,EGLN1,DMPK,ARHGAP11A,MTM1,TMSB15A,LFNG,CD82,PTTG1,APOO,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,KTN1,TNFSF9,APPBP2,RCN1,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,MX1,SNX8,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SYNE2,SAT1,SYP,RAB38,DNAJB14,SNX12,TRIM7,NFIX,IRS2,SPIN3,CCNB3,CDK19,CORO1C,SLC9A6,AXL,INPP4B,PDXK,RGS14,GEN1,ARNT,MAPK12,TTC8,FARP1,TAOK2,TRAF2,BIK,CTSZ,ANO9,PKN1,ETS1,IFT27,SLC25A43,ARHGEF40,TSPAN17,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,CXCL16,ANK1,PDCD10,FUT2,ITGB8,IRAK1,KNDC1,KCNK5,GPC3,CALD1,MCF2L,ALG13,FDXR,BAX,PLEKHF1,ADAM15,TMBIM6,WWP1,MAPK11,NKAPP1,RAG1,ADAMTS2,PLSCR1,CTNNAL1,BCL9,RAPGEF2,DUSP23,PIK3R1,NUB1,CXorf57,PLEKHA7,UBE2A,AK4,RAB3IP,SNTB1,TXK,CNTNAP1,PITX2,BTG1,PROM1,CCDC6,RAB11FIP2,NR1D2,ACVRL1,FAM3C,PPM1H,FBXO44,CENPE,ITGAV,HMGA1,FHL1,NUP37,CD81,SRSF9,FOXA1,TNK1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,NUP62CL,PDGFB,PIGL,SPTB,PLS3,BTG3,INPP5E,RPS6KA2,PCNA,NUP210,SHC3,CNTRL,ARL1,MKRN3,IL6ST,LMAN2L,PAPSS1,ELF5,DUSP10,RGS5,TNFRSF18,SCARA3,MYBL1,TRAM1,ZNF462,PLK1,KRT80,THRB,PCGF5,MARK1,PTPN18,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,ZBTB7B,RHEB,PLEKHB1,VCP,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,WIPI1,HOXA9,CTNND1,KLF11,KPNA2,PIK3C2B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,DNAJB2,RASA2,PSMD7,RACGAP1,ADCK5,RAB6A,HES2,CNTNAP2,DHRS3,CORO1B,BMP2,IGF1R,TIMP1,SPIN4,GATA2,PIM1,PLCB2,ALDH3A2,WDR72,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,BCL2L13,G2E3,CDK5R1,RASGRP2,FOXD2,DHDH,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,RAD21,USP43,NF2,UPF3B,FOXM1,DGKA,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,LPIN3,PCBP1,STIL,BCAP31,RAD23A,CDK14,SRPX,WDR44,TACC2,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,FAR1,DVL2,SULF2,SIRT1,AKT1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,IDE,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,ANXA9,RPL22,ARHGAP4,CMTM4,ZMAT1,BIN1,PINK1,DYRK3,GOLIM4,TAB3,KLHL13,GNAL,PSMD10,GDF15,NKRF,HMGN3,JAG2,LBR,PPP2R3A,SIRPA,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,CDK16,MAGEE1,UBE2J1,GTF2F2,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,CAMK2G,ATP2B1,DUSP1,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,HMGN5,CRIP2,LITAF,MAML2,TRIM35,COL7A1,AKAP3,BCAR1,DGKE,PRDX4,BCL10,USP6,DDX23,CNOT2,SERPINA1,FAT4,NEIL3,E2F1,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GAA,ACVR1,HSPG2,VANGL1,TSC22D3,PPFIBP2,GATA3,CUL1,CAMK1D,CCNB1,PICK1,SLC9A7,PAK6,ZFP36,RGS3,OSBPL3,PRICKLE3,IQCE,FOSB,POLL,SNX16,TFG,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,BNIP3L,AURKB,PIF1,GALNT7,SAV1,CCNF,SLC25A5,TP53I3,RAB2B,ULK2,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,SH2D3C,PPP2R4,LRIG1,NKD1,MAPK13,SERPINI1,SPRY4,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,PRKAA1,DGKQ,KIF23,AKAP17A,NOTCH2,S100A2,TNFRSF19,TSPAN7,PSIP1,BMP2K,MECOM,RALGPS2,ITGA3,SNX18,BHLHE41,RPL39,AIM1,PPP4R1,MSH2,DAPK1,ADCK2,PRKG1,CD70,TNFRSF12A,PIKFYVE,RIMS2,EEF1D,SOCS5,PIGC,DDB2,KCNJ12,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,WHSC1,KDM3A,FBXO10,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,TCEAL4,PIAS2,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,IRF1,PKD1L2,FRMPD3,ELK4,PLA2G4A,SPRED1,KIF3C,REPS2,ARMCX3,TRIP10,NDRG1,SUZ12,RPS6KA1,IRX4,BCL2L1,CD274,FLT3,DDR1,GNB2,ZFYVE9,EPM2A,APOBEC3B,NOV,CCNA2,ZNF75D,RALB,DOK4,CDKN1B,TNPO2,EPHB4,PDE4D,PHKA2,MYO5B,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,BCL7B,CBL,ITPR3,ASB13,FZD7,ZMPSTE24,CMTM7,NIN,EPHA10,FYN,PPP2R5A,JAK1,NGFRAP1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,MLKL,ZC3H12B,CBX7,PRKAR1A,OTUD5,IER5L,ARHGEF3,CENPI,ARL4C,CBLL1,HERC5,PLD2,FBXO6,DNAH3,PNPLA5,EFNB1,FGF19,COX7A2,SCML1,RND1,WWP2,E2F7,GNB5,RNF128,DRAM1,SGK3,ERCC2,ERBB3,MAP3K7,TRIM62,SPRY2,NCOA2,MSH6,SMC4,RASGRF1,TGIF1,ZWINT,ALDH2,CASK,LONRF3,MPP1,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,FOS,KIF11,GPLD1,CDK5RAP1,CRTC2,TIMP3,RCBTB2,FGFR2,AMMECR1,CSTF2,SERPINB5,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,PLAC1,KIF2C,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,CDKL5,ZCCHC12,TSPAN6,CAPG,POF1B,ASH2L,RAB20,RP2,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TRIM8,CENPA,FOPNL,ACBD3,USP18,ITCH,RGAG1,ROR1,STK17B,ADRBK2,TCN2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,GLA,RAP1GAP,PPP2R5D,NR2C2,CD99,ARAP3,PPP1R2,PPP1R12A,SERPINE2,ETV5,ASB9,DUSP5,SPP1,PFKL,OCRL,PRKCI,SRP54,BRAT1,KNTC1,ZRANB1,ETV7,SNX7,HP1BP3,ELK3,FBXO8,RNF113A,PDIK1L,RANBP9,EGFR,MUM1L1,BCAR3,XKRX,INSR,UAP1,NFKBIA,PAPD5,RAB31,ALPK3,RHOBTB2,PITPNA,SHROOM2,JAK3,TOB1,RARG,FBXW5,CCNE2,PAX6,SPC25,HDAC11,MORC4,COL18A1,MRAS,ARHGEF16,MXD1,SS18,SMO,TWIST1,APIP,LOXL1,HSPA2,SCYL3,EBAG9,CKS2,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,CDC25C,FANCE,KCTD2,PDHX,MAP3K6,CASP4,SOCS3,STAT6,BHLHB9,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,ARHGEF7,SERPINB9,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,ITGA2B,HDAC9,IL17RB,TOP2A,SNX13,CARD8,ADRBK1,LLGL2,MYCL,BMP7,ACTA2,TRIM3,CKS1B,MXD3,HSPA13,RPGR,MYO5A,PGM1,ADAM17,RAB3B,WNT10B,ASPM,SYBU,MBNL3,RUNX3,POLD3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,CASP7,RND3,HNRNPH2,RAP2C,UBE2D2,ZMIZ1,GEM,L1CAM,AHR,RAB3IL1,NGEF |
| 1.081e-28 | -64.39 | renal_cell_carcinoma | COSMIC cancer mutations | renal_cell_carcinoma | 4650 | 911 | 17775 | 2585 |
KLK10,TRIM24,GRIK2,AASS,AK7,TRIM5,DNAJC3,RET,MCOLN3,SMARCAL1,XIAP,MMADHC,FBXO2,DHX8,MORF4L2,SYTL4,LACTB2,SNX9,BARD1,SPSB1,CARD10,PHF1,ZNF275,GRM5,CDKN2C,TP73,DAPK2,WEE1,RGS12,PPP1R16A,ALDH1A3,KLF3,FUT1,PPP1CA,TINAGL1,PIK3CD,RNF26,WBP4,TIAM1,APOBEC3G,NEK4,SMARCA2,FBXL16,SH3BGRL,UXT,RNF11,PRKAR2B,LOXL2,PPP1R14C,ICMT,ARF4,LCP1,PIAS3,PLCG1,TRIM47,MID1IP1,WDR11,LIMK1,MYLK,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,ZNRF3,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RAC2,WDFY1,RIMS3,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,USP1,USP38,ALPK1,MAPK7,ZMYM1,DGKG,KANK3,NUP85,PHKG2,UFD1L,STAT4,MYBL2,SRSF5,ELK1,TP53INP2,GNA11,RHOB,STK17A,DHX32,PTPRF,MAGED2,NCOA3,ETS2,HTT,TIMM8A,ITPR1,DGAT2,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,CBX5,RPS6KA3,ADAMTS16,EGLN1,DMPK,ARHGAP11A,MTM1,TMSB15A,LFNG,CD82,PTTG1,APOO,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,KTN1,TNFSF9,APPBP2,RCN1,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,MX1,SNX8,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SYNE2,SAT1,SYP,RAB38,DNAJB14,SNX12,TRIM7,NFIX,IRS2,SPIN3,CCNB3,CDK19,CORO1C,SLC9A6,AXL,INPP4B,PDXK,RGS14,GEN1,ARNT,MAPK12,TTC8,FARP1,TAOK2,TRAF2,BIK,CTSZ,ANO9,PKN1,ETS1,IFT27,SLC25A43,ARHGEF40,TSPAN17,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,CXCL16,ANK1,PDCD10,FUT2,ITGB8,IRAK1,KNDC1,KCNK5,GPC3,CALD1,MCF2L,ALG13,FDXR,BAX,PLEKHF1,ADAM15,TMBIM6,WWP1,MAPK11,NKAPP1,RAG1,ADAMTS2,PLSCR1,CTNNAL1,BCL9,RAPGEF2,DUSP23,PIK3R1,NUB1,CXorf57,PLEKHA7,UBE2A,AK4,RAB3IP,SNTB1,TXK,CNTNAP1,PITX2,BTG1,PROM1,CCDC6,RAB11FIP2,NR1D2,ACVRL1,FAM3C,PPM1H,FBXO44,CENPE,ITGAV,HMGA1,FHL1,NUP37,CD81,SRSF9,FOXA1,TNK1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,NUP62CL,PDGFB,PIGL,SPTB,PLS3,BTG3,INPP5E,RPS6KA2,PCNA,NUP210,SHC3,CNTRL,ARL1,MKRN3,IL6ST,LMAN2L,PAPSS1,ELF5,DUSP10,RGS5,TNFRSF18,SCARA3,MYBL1,TRAM1,ZNF462,PLK1,KRT80,THRB,PCGF5,MARK1,PTPN18,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,ZBTB7B,RHEB,PLEKHB1,VCP,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,WIPI1,HOXA9,CTNND1,KLF11,KPNA2,PIK3C2B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,DNAJB2,RASA2,PSMD7,RACGAP1,ADCK5,RAB6A,HES2,CNTNAP2,DHRS3,CORO1B,BMP2,IGF1R,TIMP1,SPIN4,GATA2,PIM1,PLCB2,ALDH3A2,WDR72,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,BCL2L13,G2E3,CDK5R1,RASGRP2,FOXD2,DHDH,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,RAD21,USP43,NF2,UPF3B,FOXM1,DGKA,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,LPIN3,PCBP1,STIL,BCAP31,RAD23A,CDK14,SRPX,WDR44,TACC2,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,FAR1,DVL2,SULF2,SIRT1,AKT1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,IDE,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,ANXA9,RPL22,ARHGAP4,CMTM4,ZMAT1,BIN1,PINK1,DYRK3,GOLIM4,TAB3,KLHL13,GNAL,PSMD10,GDF15,NKRF,HMGN3,JAG2,LBR,PPP2R3A,SIRPA,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,CDK16,MAGEE1,UBE2J1,GTF2F2,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,CAMK2G,ATP2B1,DUSP1,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,HMGN5,CRIP2,LITAF,MAML2,TRIM35,COL7A1,AKAP3,BCAR1,DGKE,PRDX4,BCL10,USP6,DDX23,CNOT2,SERPINA1,FAT4,NEIL3,E2F1,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GAA,ACVR1,HSPG2,VANGL1,TSC22D3,PPFIBP2,GATA3,CUL1,CAMK1D,CCNB1,PICK1,SLC9A7,PAK6,ZFP36,RGS3,OSBPL3,PRICKLE3,IQCE,FOSB,POLL,SNX16,TFG,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,BNIP3L,AURKB,PIF1,GALNT7,SAV1,CCNF,SLC25A5,TP53I3,RAB2B,ULK2,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,SH2D3C,PPP2R4,LRIG1,NKD1,MAPK13,SERPINI1,SPRY4,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,PRKAA1,DGKQ,KIF23,AKAP17A,NOTCH2,S100A2,TNFRSF19,TSPAN7,PSIP1,BMP2K,MECOM,RALGPS2,ITGA3,SNX18,BHLHE41,RPL39,AIM1,PPP4R1,MSH2,DAPK1,ADCK2,PRKG1,CD70,TNFRSF12A,PIKFYVE,RIMS2,EEF1D,SOCS5,PIGC,DDB2,KCNJ12,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,WHSC1,KDM3A,FBXO10,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,TCEAL4,PIAS2,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,IRF1,PKD1L2,FRMPD3,ELK4,PLA2G4A,SPRED1,KIF3C,REPS2,ARMCX3,TRIP10,NDRG1,SUZ12,RPS6KA1,IRX4,BCL2L1,CD274,FLT3,DDR1,GNB2,ZFYVE9,EPM2A,APOBEC3B,NOV,CCNA2,ZNF75D,RALB,DOK4,CDKN1B,TNPO2,EPHB4,PDE4D,PHKA2,MYO5B,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,BCL7B,CBL,ITPR3,ASB13,FZD7,ZMPSTE24,CMTM7,NIN,EPHA10,FYN,PPP2R5A,JAK1,NGFRAP1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,MLKL,ZC3H12B,CBX7,PRKAR1A,OTUD5,IER5L,ARHGEF3,CENPI,ARL4C,CBLL1,HERC5,PLD2,FBXO6,DNAH3,PNPLA5,EFNB1,FGF19,COX7A2,SCML1,RND1,WWP2,E2F7,GNB5,RNF128,DRAM1,SGK3,ERCC2,ERBB3,MAP3K7,TRIM62,SPRY2,NCOA2,MSH6,SMC4,RASGRF1,TGIF1,ZWINT,ALDH2,CASK,LONRF3,MPP1,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,FOS,KIF11,GPLD1,CDK5RAP1,CRTC2,TIMP3,RCBTB2,FGFR2,AMMECR1,CSTF2,SERPINB5,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,PLAC1,KIF2C,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,CDKL5,ZCCHC12,TSPAN6,CAPG,POF1B,ASH2L,RAB20,RP2,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TRIM8,CENPA,FOPNL,ACBD3,USP18,ITCH,RGAG1,ROR1,STK17B,ADRBK2,TCN2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,GLA,RAP1GAP,PPP2R5D,NR2C2,CD99,ARAP3,PPP1R2,PPP1R12A,SERPINE2,ETV5,ASB9,DUSP5,SPP1,PFKL,OCRL,PRKCI,SRP54,BRAT1,KNTC1,ZRANB1,ETV7,SNX7,HP1BP3,ELK3,FBXO8,RNF113A,PDIK1L,RANBP9,EGFR,MUM1L1,BCAR3,XKRX,INSR,UAP1,NFKBIA,PAPD5,RAB31,ALPK3,RHOBTB2,PITPNA,SHROOM2,JAK3,TOB1,RARG,FBXW5,CCNE2,PAX6,SPC25,HDAC11,MORC4,COL18A1,MRAS,ARHGEF16,MXD1,SS18,SMO,TWIST1,APIP,LOXL1,HSPA2,SCYL3,EBAG9,CKS2,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,CDC25C,FANCE,KCTD2,PDHX,MAP3K6,CASP4,SOCS3,STAT6,BHLHB9,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,ARHGEF7,SERPINB9,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,ITGA2B,HDAC9,IL17RB,TOP2A,SNX13,CARD8,ADRBK1,LLGL2,MYCL,BMP7,ACTA2,TRIM3,CKS1B,MXD3,HSPA13,RPGR,MYO5A,PGM1,ADAM17,RAB3B,WNT10B,ASPM,SYBU,MBNL3,RUNX3,POLD3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,CASP7,RND3,HNRNPH2,RAP2C,UBE2D2,ZMIZ1,GEM,L1CAM,AHR,RAB3IL1,NGEF |
| 1.239e-27 | -61.96 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3789 | 767 | 17775 | 2585 |
KLK10,TRIM24,AK7,TRIM5,DNAJC3,RET,SMARCAL1,XIAP,MMADHC,FBXO2,DHX8,LACTB2,SNX9,BARD1,SPSB1,CARD10,PHF1,CDKN2C,TP73,DAPK2,WEE1,RGS12,PPP1R16A,ALDH1A3,KLF3,FUT1,PPP1CA,PIK3CD,RNF26,WBP4,TIAM1,APOBEC3G,NEK4,SMARCA2,FBXL16,RNF11,PRKAR2B,LOXL2,PPP1R14C,ICMT,ARF4,LCP1,PIAS3,PLCG1,TRIM47,WDR11,LIMK1,MYLK,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,HSPB1,GAB1,HOXC13,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,RAC2,WDFY1,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,USP1,USP38,ALPK1,MAPK7,DGKG,NUP85,PHKG2,UFD1L,STAT4,MYBL2,SRSF5,ELK1,TP53INP2,GNA11,RHOB,STK17A,DHX32,PTPRF,NCOA3,ETS2,ITPR1,DGAT2,AURKA,MDH1,GDF11,FBXO27,SERPINB1,CBX5,RPS6KA3,ADAMTS16,EGLN1,DMPK,ARHGAP11A,MTM1,LFNG,CD82,PTTG1,RGS20,TESK2,NUF2,GRK6,PRKACA,APC2,KTN1,TNFSF9,APPBP2,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,CDKN2D,ETV4,SNX10,SNX8,RIPK2,APOBEC3D,NRBF2,FZD4,PTPN9,SEPT6,PLEKHO1,RAB38,DNAJB14,SNX12,TRIM7,NFIX,IRS2,CCNB3,CDK19,CORO1C,AXL,INPP4B,PDXK,RGS14,GEN1,ARNT,MAPK12,FARP1,TAOK2,TRAF2,BIK,CTSZ,ANO9,PKN1,ETS1,IFT27,ARHGEF40,TSPAN17,SGPL1,CTNNBIP1,DIRAS3,CXCL16,ANK1,PDCD10,ITGB8,IRAK1,KNDC1,KCNK5,GPC3,CALD1,MCF2L,FDXR,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,RAG1,ADAMTS2,CTNNAL1,TACC1,BCL9,RAPGEF2,DUSP23,PIK3R1,NUB1,GRIN1,PLEKHA7,UBE2A,AK4,RAB3IP,SNTB1,TXK,PITX2,BTG1,PROM1,CCDC6,ACVRL1,NR1D2,FAM3C,NR4A3,PPM1H,FBXO44,CENPE,ITGAV,HMGA1,NUP37,CD81,SRSF9,FOXA1,TNK1,TRIM2,EPAS1,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,PIGL,BTG3,INPP5E,ENTPD4,RPS6KA2,PCNA,NUP210,CTNNB1,SHC3,CNTRL,ARL1,IL6ST,ELF5,DUSP10,RGS5,TNFRSF18,SCARA3,MYBL1,TRAM1,PLK1,THRB,KRT80,PCGF5,MARK1,PTPN18,CD55,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,RHEB,PLEKHB1,VCP,KDM4D,TRIM9,PLEKHG6,PI4K2B,KCNMB4,HOXA9,CTNND1,KLF11,KPNA2,PIK3C2B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,RASA2,DNAJB2,RACGAP1,ADCK5,RAB6A,HES2,BMP2,IGF1R,TIMP1,GATA2,PIM1,PLCB2,ALDH3A2,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,BCL2L13,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,ZDHHC7,PLD1,CCNB2,RNF146,RAD21,USP43,NF2,FOXM1,DGKA,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PCBP1,STIL,RAD23A,CDK14,TACC2,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,XRCC3,RPL22,ARHGAP4,CMTM4,BIN1,PINK1,DYRK3,GOLIM4,GNAL,PSMD10,HMGN3,GDF15,JAG2,LBR,PPP2R3A,SIRPA,DNAJB9,FZD6,ZDHHC21,FOXP2,CDK16,UBE2J1,TRIM21,SGK1,BUB1,ALDH7A1,FAIM,SYK,CAMK2G,DUSP1,DLGAP1,HES1,RHOA,CRIP2,LITAF,PPARA,MAML2,TRIM35,AKAP3,BCAR1,DGKE,DDX23,USP6,BCL10,CNOT2,SERPINA1,NEIL3,E2F1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ARHGEF4,ACVR1,TTC39B,VANGL1,PPFIBP2,CUL1,GATA3,CAMK1D,CCNB1,PICK1,PAK6,ZFP36,RGS3,OSBPL3,IQCE,FOSB,PIK3CA,POLL,SNX16,TFG,SMYD5,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,BNIP3L,AURKB,PIF1,CCNF,SAV1,TP53I3,RAB2B,ULK2,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,SH2D3C,PPP2R4,NKD1,LRIG1,MAPK13,SERPINI1,SPRY4,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,DGKQ,PRKAA1,KIF23,NOTCH2,S100A2,TNFRSF19,PSIP1,BMP2K,MECOM,CALR,RALGPS2,ITGA3,SNX18,BHLHE41,PPP4R1,MSH2,DAPK1,ADCK2,PRKG1,TNFRSF12A,CD70,PIKFYVE,EEF1D,RIMS2,SOCS5,PIGC,DDB2,PRODH,KLK5,ADCK3,PIP4K2C,WHSC1,KDM3A,FBXO10,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,PIAS2,KLK7,NR4A2,CDK18,MAP3K5,NRBP1,IRF1,ELK4,PLA2G4A,SPRED1,TRIP10,NDRG1,SUZ12,RPS6KA1,THRA,IRX4,BCL2L1,CD274,FLT3,DDR1,GNB2,ZFYVE9,EPM2A,APOBEC3B,NOV,CCNA2,RALB,DOK4,TNPO2,CDKN1B,PDE4D,EPHB4,NR2C1,MED30,FOXJ2,PRKCQ,PKMYT1,PYGO1,BCL7B,CBL,ASB13,ITPR3,FZD7,ZMPSTE24,CMTM7,NIN,EPHA10,FYN,PPP2R5A,JAK1,NGFRAP1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,MLKL,CBX7,PRKAR1A,IER5L,ARHGEF3,ARL4C,CBLL1,HERC5,PLD2,FBXO6,FGF19,COX7A2,SCML1,RND1,WWP2,E2F7,RNF128,GNB5,PTEN,DRAM1,SGK3,ERCC2,ERBB3,MAP3K7,TRIM62,SPRY2,NCOA2,MSH6,SMC4,RASGRF1,TGIF1,ZWINT,ALDH2,CASK,LONRF3,FURIN,FBXO9,YES1,FOS,KIF11,GPLD1,CRTC2,CDK5RAP1,TIMP3,RCBTB2,FGFR2,SERPINB5,FZD5,NCAPG2,ESPL1,MELK,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,KIF2C,KREMEN1,DENND2D,ABCD4,ARHGEF10L,RAB15,LRRC6,CDKL5,CAPG,RAB20,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TRIM8,CENPA,USP18,ACBD3,ITCH,ROR1,STK17B,ADRBK2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,RAP1GAP,PPP2R5D,NR2C2,ARAP3,PPP1R2,SERPINE2,PPP1R12A,ETV5,ASB9,DUSP5,PFKL,OCRL,PRKCI,SRP54,BRAT1,KNTC1,ZRANB1,ETV7,SNX7,ELK3,FBXO8,PDIK1L,RANBP9,EGFR,BCAR3,INSR,UAP1,NFKBIA,PAPD5,RAB31,ALPK3,RHOBTB2,PITPNA,JAK3,TOB1,RARG,FBXW5,CCNE2,PAX6,SPC25,HDAC11,MRAS,ARHGEF16,MXD1,SS18,TWIST1,APIP,LOXL1,HSPA2,SCYL3,EBAG9,CKS2,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,CDC25C,KCTD2,FANCE,CASP4,MAP3K6,PDHX,SOCS3,STAT6,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,ARHGEF7,SHPRH,SERPINB9,TGFBR1,TRIB2,HMGXB4,ITGA2B,HDAC9,IL17RB,TOP2A,SNX13,CARD8,ADRBK1,LLGL2,MYCL,BMP7,TRIM3,CKS1B,MXD3,HSPA13,PGM1,ADAM17,RAB3B,NR4A1,ASPM,SYBU,RUNX3,POLD3,FOXL1,KLHL2,ARHGAP24,SWAP70,CASP7,RND3,RAP2C,UBE2D2,ZMIZ1,SOX8,GEM,AHR,RAB3IL1,NGEF |
| 2.109e-27 | -61.42 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | 436 | 153 | 17758 | 2588 |
CASP3,BCAM,TTC39B,EPAS1,FAM160B1,TMEM41B,ATP8A1,PPFIBP2,SLC20A1,SDC1,KREMEN1,ZNF275,ZNF823,CTNNB1,ARHGEF37,ZFP36,KLF3,ALDH1A3,AOX1,CLDN4,RAB20,TACSTD2,S100A13,CD55,SH3BGRL,RNF11,EZR,KDELR3,GALNT7,PTGFRN,LHFPL2,ARF4,MFAP3L,ENPP1,PI4K2B,TRAM2,WIPI1,PLK2,FAM114A1,FAM110C,CAB39,CTNND1,TTC9,EPB41L4A,TRAF5,GLCCI1,GAB1,TC2N,NXT2,TMTC3,ASAH1,DOCK11,ZNF432,DOPEY2,GATA2,FAM20C,KIF13B,LIMCH1,FAM84B,NCEH1,ULBP2,SLC12A2,IGSF3,PQLC3,CORO2A,PIP4K2C,EPN3,IL1R1,FNTA,SH3BP4,ZDHHC7,MAL2,KLF7,PROM2,EHD1,SPRED1,LFNG,ATP2C2,ERBB2,CCDC68,IL13RA1,FAM198B,CDS1,APLP2,EFR3A,REEP1,ZDHHC23,CDH3,EPB41L4B,LRP11,TSPAN1,RAB27B,EGLN3,LOXL1,HSPA2,TIMP2,RFK,FZD4,SAT1,UTRN,SLC11A2,ALCAM,DAG1,OSBPL2,PTPRJ,ZNF704,PPP1CB,VSIG10,PDXK,ST3GAL1,KDELC2,ANXA3,SH3D19,BIK,ARL4C,PBX3,GDF15,NUCB2,NFAT5,PARM1,TMEM87B,BMP7,DRAM1,ATP8B1,SLC44A2,TSPAN13,KLF9,TRIM62,ATP2B1,PHF20L1,B3GNT2,RHOA,TACC1,PLEKHA7,LITAF,SPAG1,GALNT3,FUCA1,TMEM50B,TIMP3,LDLRAP1,SWAP70,ACADSB,TWSG1,DBI,ARRB1,ARFGAP3,PKD2,FZD5,NDFIP1,CPEB2,AHR,USP16 |
| 2.218e-27 | -61.37 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4587 | 895 | 17775 | 2585 |
KLK10,TRIM24,AASS,AK7,TRIM5,DNAJC3,RET,SMARCAL1,CACNA2D2,XIAP,FBXO2,MMADHC,DHX8,MORF4L2,SYTL4,LACTB2,SNX9,BARD1,SPSB1,CARD10,PHF1,ZNF275,CDKN2C,TP73,DAPK2,WEE1,ZYX,RGS12,MUC4,PPP1R16A,ALDH1A3,KLF3,FUT1,PPP1CA,PIK3CD,RNF26,WBP4,TIAM1,APOBEC3G,NEK4,NWD1,SMARCA2,FBXL16,SH3BGRL,UXT,RNF11,PRKAR2B,LOXL2,PPP1R14C,ICMT,RNF19B,ARF4,LCP1,PIAS3,PLCG1,TRIM47,MID1IP1,WDR11,LIMK1,MYLK,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,ZNRF3,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RAC2,WDFY1,FRY,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,USP1,USP38,ALPK1,MAPK7,DGKG,NUP85,PHKG2,UFD1L,STAT4,MYBL2,SRSF5,ELK1,TP53INP2,DPYSL4,GNA11,RHOB,STK17A,DHX32,PTPRF,MAGED2,NCOA3,ETS2,TIMM8A,ITPR1,DGAT2,CLMN,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,CBX5,RPS6KA3,ADAMTS16,EGLN1,DMPK,ARHGAP11A,MTM1,TMSB15A,LFNG,CD82,PTTG1,APOO,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,KTN1,TNFSF9,APPBP2,CCND1,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,SNX8,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,SYP,RAB38,DNAJB14,SNX12,TRIM7,NFIX,IRS2,SPIN3,CCNB3,CDK19,CORO1C,SLC9A6,AXL,INPP4B,PDXK,RGS14,GEN1,ARNT,MAPK12,FARP1,TAOK2,TRAF2,BIK,CTSZ,ANO9,PKN1,ETS1,IFT27,SLC25A43,ARHGEF40,TSPAN17,NFAT5,SRPX2,BEX2,PDIA4,SGPL1,CTNNBIP1,DIRAS3,ZFX,CXCL16,ANK1,PDCD10,ITGB8,IRAK1,KNDC1,KCNK5,GPC3,CALD1,ALG13,MCF2L,FDXR,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,RAG1,ADAMTS2,CTNNAL1,BCL9,RAPGEF2,DUSP23,PIK3R1,NUB1,CXorf57,PLEKHA7,UBE2A,AK4,RAB3IP,SNTB1,TXK,PITX2,BTG1,PROM1,CCDC6,NR1D2,ACVRL1,FAM3C,PPM1H,FBXO44,CENPE,ITGAV,HMGA1,FHL1,NUP37,CD81,SRSF9,FOXA1,TNK1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,NUP62CL,PIGL,PLS3,BTG3,INPP5E,RPS6KA2,PCNA,NUP210,CTNNB1,SHC3,CNTRL,ARL1,IL6ST,ELF5,DUSP10,RGS5,TNFRSF18,SCARA3,MYBL1,TRAM1,PLK1,THRB,KRT80,PCGF5,PTPN18,MARK1,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,RHEB,PLEKHB1,VCP,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,HOXA9,CTNND1,KLF11,KPNA2,PIK3C2B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,DNAJB2,RASA2,RACGAP1,ADCK5,RAB6A,HES2,CNTNAP2,RB1,DAZAP1,IGF1R,TIMP1,SPIN4,GATA2,PIM1,PLCB2,ALDH3A2,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,BCL2L13,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,RAD21,USP43,NF2,UPF3B,FOXM1,DGKA,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PCBP1,STIL,BCAP31,PER2,RAD23A,CDK14,SRPX,WDR44,TACC2,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,FIGNL1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,RPL22,ARHGAP4,CMTM4,ZMAT1,BIN1,PINK1,DYRK3,GOLIM4,TAB3,KLHL13,MACC1,GNAL,PSMD10,GDF15,NKRF,HMGN3,JAG2,LBR,VPS26A,PPP2R3A,SIRPA,DNAJB9,FZD6,ZDHHC21,FOXP2,CDK16,MAGEE1,UBE2J1,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,CAMK2G,ATP2B1,DUSP1,WBP5,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,HMGN5,CRIP2,LITAF,MAML2,TRIM35,AKAP3,BCAR1,DGKE,PRDX4,USP6,BCL10,DDX23,CNOT2,SERPINA1,NEIL3,E2F1,PGRMC1,PPP2R3C,SH3BGRL2,PKD2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,ACVR1,LGR4,VANGL1,FAM129B,TSC22D3,PPFIBP2,GATA3,CUL1,CAMK1D,CCNB1,PICK1,SLC9A7,PAK6,ZFP36,RGS3,OSBPL3,PRICKLE3,IQCE,FOSB,PIK3CA,POLL,SNX16,TFG,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,BNIP3L,AURKB,PIF1,SAV1,CCNF,SLC25A5,TP53I3,RAB2B,ULK2,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,TBX1,SH2D3C,PPP2R4,LRIG1,NKD1,MAPK13,SERPINI1,SPRY4,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,DGKQ,PRKAA1,KIF23,AKAP17A,NOTCH2,S100A2,TNFRSF19,TSPAN7,PSIP1,BMP2K,MECOM,RALGPS2,ITGA3,SNX18,BHLHE41,RPL39,PPP4R1,MSH2,DAPK1,ADCK2,PRKG1,CD70,TNFRSF12A,PIKFYVE,KCTD3,RIMS2,EEF1D,SOCS5,PIGC,DDB2,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,WHSC1,VEZT,KDM3A,FBXO10,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,TCEAL4,PIAS2,PCDH19,KLK7,CDK18,MAP3K5,NRBP1,IRF1,FRMPD3,ELK4,PLA2G4A,PLEKHG3,SPRED1,REPS2,CAPN12,ARMCX3,TRIP10,NDRG1,SUZ12,RPS6KA1,IRX4,BCL2L1,CD274,FLT3,DDR1,GNB2,ZFYVE9,EPM2A,APOBEC3B,NOV,CCNA2,ZNF75D,RALB,DOK4,CDKN1B,TNPO2,PDE4D,EPHB4,PHKA2,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,BCL7B,C15orf39,CBL,ASB13,ITPR3,FZD7,ZMPSTE24,CMTM7,NIN,EPHA10,FYN,PPP2R5A,JAK1,NGFRAP1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,MLKL,ZC3H12B,CBX7,PRKAR1A,OTUD5,IER5L,ARHGEF3,CENPI,ARL4C,CBLL1,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,HLA-A,SCML1,RND1,WWP2,E2F7,RNF128,GNB5,PTEN,DRAM1,SGK3,ERCC2,ERBB3,MAP3K7,SPRY2,TRIM62,NCOA2,MSH6,SMC4,RASGRF1,TGIF1,ZWINT,ALDH2,CASK,LONRF3,MPP1,FURIN,C1GALT1C1,DIAPH2,FBXO9,YES1,FOS,KIF11,GPLD1,CDK5RAP1,CRTC2,TIMP3,RCBTB2,FGFR2,AMMECR1,CSTF2,SERPINB5,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,PLAC1,KIF2C,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,CDKL5,ZCCHC12,TSPAN6,CAPG,POF1B,KIF22,ASH2L,RAB20,RP2,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TRIM8,CENPA,ASXL1,USP18,ACBD3,ITCH,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ZNF114,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,GLA,RAP1GAP,PPP2R5D,NR2C2,CD99,ARAP3,PPP1R2,PPP1R12A,SERPINE2,PEX6,ETV5,ASB9,DUSP5,SPP1,PFKL,OCRL,PRKCI,SRP54,FNIP1,BRAT1,KNTC1,ZRANB1,ETV7,SNX7,ELK3,FBXO8,RNF113A,PDIK1L,RANBP9,EGFR,MUM1L1,GNAS,BCAR3,XKRX,INSR,UAP1,NFKBIA,PAPD5,RAB31,ALPK3,RHOBTB2,PITPNA,SHROOM2,JAK3,TOB1,RARG,FBXW5,CCNE2,PAX6,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,MXD1,SS18,FRYL,SMO,TWIST1,APIP,LOXL1,HSPA2,SCYL3,EBAG9,CKS2,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,CDC25C,FANCE,KCTD2,PDHX,MAP3K6,CASP4,SOCS3,HSF4,STAT6,BHLHB9,CANT1,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,ARHGEF7,SERPINB9,TGFBR1,COL4A5,TRMT2B,TRIB2,HMGXB4,ITGA2B,HDAC9,IL17RB,TOP2A,SNX13,CARD8,ADRBK1,LLGL2,MYCL,TOX2,TRIM3,CKS1B,MXD3,HSPA13,RPGR,MYO5A,PGM1,ADAM17,RAB3B,WNT10B,SYBU,MBNL3,RUNX3,POLD3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,CASP7,RND3,HNRNPH2,RAP2C,UBE2D2,ZMIZ1,GEM,L1CAM,AHR,RAB3IL1,NGEF |
| 6.830e-27 | -60.25 | intracellular part | cellular component | GO:0044424 | 13357 | 2167 | 17570 | 2579 |
HECA,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,SPSB1,GRM5,UBE2T,ATP13A3,DNM2,PPP1CA,CPE,DNAAF3,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,LCP1,ABR,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,GGA1,SEC61G,MTL5,RAB23,GPSM2,FAM21C,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,USP1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,PPP6R1,MCCC2,REC8,PYM1,FHL2,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,PLIN5,ETS2,DGAT2,GDF11,TMEM173,DMPK,C5orf30,MAPK4,MGST2,RBM23,MUC16,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,SEPT6,PTPN9,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,GTF2A2,SNX12,TRIM7,ZNF618,NFIX,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,SLC25A30,CTHRC1,HSP90B1,CKAP2,BACE1,ESRP1,DCAF7,CCM2,BIK,SDC4,HABP4,FLOT1,CTSZ,ZNF219,HDGFRP2,NFAT5,BEX2,GPC3,MGAT4A,TUBGCP6,KLC3,BAX,IGFBP2,MED22,ACBD5,TACC1,PIK3R1,DUSP23,MRS2,NUB1,PGBD1,RAB3IP,PIM3,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,WDR45B,SRSF9,ACOT7,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,INPP5E,BTG3,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,ARFRP1,DZIP1L,TRIM9,PI4K2B,HOXA9,ARRDC1,KLF11,RUNX2,LMTK3,PARP12,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,KIF13B,TBCD,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,NTN1,DPYSL5,USP31,EMC2,STRADB,ZSCAN12,PDK3,PRX,CDK5R1,COL13A1,PHLPP2,KBTBD2,NLRC5,PLD1,AKIP1,CCNB2,CDAN1,USP43,HOXB7,RHPN2,PCBP1,BCAP31,IER3,KMT5C,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,ACO1,CFAP36,ATP13A2,ZNF628,IDE,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ARFGEF3,ZMAT1,PINK1,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,UBE2J1,ALDH7A1,CPLX1,ATP2B1,GCNT1,DUSP1,NFE2L3,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,HELZ2,TYMP,ANKS6,OSBPL3,PALD1,FOSB,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,SH2D3C,BMP1,NFKBIZ,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,BHLHE41,PPP4R1,MSH2,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,PYGL,ATP8B3,PLEKHH2,TJP3,AGBL5,PIAS2,APPL2,SFMBT1,KLK7,SAMD8,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,PDE4D,OSBPL7,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,MSANTD4,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PYGO1,PKMYT1,CBL,B3GALNT2,TRIQK,CEP162,ACAD10,NGFRAP1,TRIOBP,CBX7,MAMDC2,DEPDC1,IGFBP6,EPS8,HERC5,PLD2,FBXO6,SPDL1,EFNB1,COX7A2,WWP2,SCML1,SLC25A36,E2F7,RNF128,GNB5,CD9,CITED2,TTPA,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,CPTP,DCTN6,ACADSB,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,ESPL1,DEF6,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,ZFYVE16,HSF2,CASC4,ARHGEF37,METTL7A,CDKL5,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,SUCO,PRKCI,BRAT1,GAD1,ETV7,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,STEAP1,RANBP9,SOX13,UAP1,SPAG7,RAB31,DCUN1D1,CTSA,TOB1,RARG,AFAP1,SNX30,NBPF1,LZTFL1,DYNLRB1,SORBS1,PAX6,PDIA5,COL18A1,SAYSD1,PHLDA1,ZNF687,COX14,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CHP1,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ARHGEF7,TGFBR1,NTAN1,SBF1,XPR1,TMEM63A,KIF5B,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,DCAF6,RC3H2,SYBU,RGCC,LEMD2,ARHGAP24,CTSL,CASP7,TRIM69,SPINT2,RAP2C,DTX4,UACA,ARRB1,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CNTROB,MORF4L2,SYTL4,BARD1,PHF1,DAPK2,ZYX,AP1M2,TGFBR3,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,ILK,DCP2,CYB5A,STK17A,DHX32,NAAA,NCOA3,MTFMT,HTT,SETD3,TEX30,ITPR1,AURKA,GSKIP,ALG2,B4GAT1,MAL2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,NUF2,KTN1,CDS1,CCND1,SCNN1A,RNF220,ACSL4,RAB27B,CDKN2D,TMEM9,RNF169,SCN3A,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TNRC6C,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ETS1,ARHGEF40,TSPAN17,SRPX2,DTX3L,CAPN2,ADD3,ARSG,FAM160A2,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,POU6F1,NUDT8,LCA5,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,DCAF10,PITX2,CCDC6,ATXN7L3,NR1D2,ARFGAP3,FHL1,SHOX2,UNKL,UNC93B1,TRIM2,AGRN,GNPDA1,EPHA4,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,TRAM1,DDX59,NEB,CCDC38,PCGF5,CITED4,ERP44,ESYT1,ANLN,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,UBASH3B,ASAH1,DOCK11,PGAP1,GATA2,CMTR2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,KCNAB3,NF2,UGP2,DGKA,ERBB2,RASGRP3,KBTBD11,CYP26A1,C1orf116,CDK14,RAD23A,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,ATP1A1,PSMD3,RPL22,AIFM3,ZNF701,COPG1,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,SWI5,PSMD10,NKRF,PPP2R3A,MTRNR2L1,CEP97,BUB1,HEXIM2,FAIM,CAMK2G,MLEC,IFITM3,NR3C1,AMFR,LITAF,CARD19,FXR2,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,TMEM50B,NAT1,ZNF214,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,CFAP74,PPP4R4,ATP8A1,KLC2,PLXNA1,CCNB1,RIC1,SESN3,CTGF,ZFP36,STEAP2,AOX1,RCAN3,TFG,LAMP2,LOC81691,SNTB2,PBK,CASP9,TNS1,PIF1,GALNT7,SLC17A5,CCNF,SFXN1,KDSR,HLF,RBM47,PLK2,TBX1,NKD1,DHTKD1,SARAF,EIF4EBP2,TMEM8B,TRAF5,LZTS1,DLAT,KLF2,MRPL44,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,AMER1,PIP4K2C,CYFIP2,KDM3A,RASA1,FAS,PRKAG2,CSNK1G1,NAB2,TCEAL4,NRBP1,IRF1,PLA2G4A,FRMPD3,ELK4,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,RNF182,EGR3,SNN,NUDT12,GNB2,SLC25A35,APLP2,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,JAK1,CFAP45,STK26,NRG1,RAB29,B4GALT3,ATMIN,OTUD5,NUDT6,ARHGEF3,ANKRD13D,ARL4C,CDCA3,APOBEC3H,TEAD3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,PRC1,SGK3,ATP8B1,ERCC2,CNOT6L,CNPY3,PCCB,SHMT1,CASK,DENND1B,MPP1,TEF,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,SLC25A40,CSTF2,PGM2L1,ETAA1,SLC25A38,CPEB2,OCLN,CAMKK1,HEBP1,UBE2Z,TAF6L,CACNB4,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,PHTF1,KIF22,SUN3,RAB20,NFU1,MYH14,PTPRE,TRIM8,ASCL5,SYNE3,ROR1,TCN2,EDNRA,MDK,CXXC4,ZNF114,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,PIFO,PEX6,ASL,PHLPP1,EBF4,HP1BP3,GYLTL1B,HMG20B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,PLPP3,NFKBIA,CDCA5,RHOBTB2,ALPK3,KIF12,PROM2,SPC25,TDRKH,ZMYND10,ARHGEF16,SLC25A48,SS18,ZDHHC12,FRYL,SMO,GOT1,STEAP3,RPN2,APIP,F2R,LOXL1,SCYL3,MAP3K3,GCA,ZNF525,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,JKAMP,FRMD6,ARMC7,TRMT2B,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,CENPC,MBNL3,OGDHL,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,ZNF596,SNPH,IBTK,AK7,GRIK2,SLC25A13,RET,TRAPPC8,LACTB2,ISOC2,SNX9,CARD10,ZNF275,CDKN2C,NPM2,NAPG,MUC4,CRY2,WBP4,TIPARP,TIAM1,MGAT5,DSTN,TMEM98,CDA,PRKAR2B,RNF19B,GINS4,ARF4,PLCG1,CARHSP1,ENPP1,ATP7B,CELF5,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,ATP5H,RANBP1,FBXO7,PCYOX1,CADPS2,SLAIN2,MYDGF,FAM84B,ZMYM1,MYLIP,DGKG,PHKG2,HPS3,PQLC3,MAPKAPK3,SHARPIN,ERO1A,KIF20B,SFXN5,GNA11,PSMA4,IL1R1,FNTA,APMAP,S100A5,CLMN,STK39,CFAP20,CBX5,NUP58,RUSC1,DOCK9,NQO1,LFNG,INPP5D,PTTG1,APOO,MVB12B,MOCS1,APPBP2,RCN1,CDH1,SH3BP1,XYLT2,RASGEF1A,DLG3,ETV4,SNX10,MX1,COL6A2,SEC61B,PFKFB2,SAT1,EBF2,COX20,GABARAPL1,ALDH3B1,CCNB3,PNPLA6,ISOC1,MAPK12,MZT1,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,SLC25A45,ZFX,PDCD10,FUT2,KNDC1,CST3,FAM20B,RAG1,PARP9,OPLAH,PLSCR1,UBE2A,AK4,C4orf27,RGPD5,RPL12,PROM1,LDLRAP1,PLOD2,DBI,NR4A3,PPM1H,SSNA1,ITGAV,OSR1,CMPK2,PHC1,ILDR1,LMCD1,DNAJB11,GALM,ITPR2,SPTB,FANCI,TFAP2E,CPNE2,CTNNB1,TM9SF2,NPNT,ARL1,PASK,MITF,SLC44A1,PAPSS1,PSMC2,SCARA3,KRT80,THRB,PLK1,KCNIP3,CELSR2,CKAP2L,CCBL2,EAF2,SESN1,KDM4D,TNS4,PLEKHG6,HS6ST1,KLF12,AGPAT2,ZNF367,KPNA2,MYL12B,TC2N,RRAGD,HJURP,LGALS3,DNAJB2,PDCL,ADCK5,SORBS3,HES2,RAB6A,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FOXD2,FA2H,P4HA3,ZDHHC7,FAM213A,RAD21,CTDSPL,TP53,P2RX7,BAHD1,EMP2,STIL,SYTL2,TMSB15B,PDGFA,TTC21B,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,STK38,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,LBR,AIP,SH2D4A,FZD6,PARM1,VPS26A,M6PR,TBC1D31,CDK16,TFAP2A,FAM63A,GTF2F2,TRIM21,SGK1,HMGCL,SYK,WBP5,P2RX4,HES1,HMGN5,GUSB,PLAUR,CRIP2,STMN3,PRICKLE1,MAML2,BBS2,RNPEP,TXNDC11,DGKE,BCL10,USP6,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ARHGEF9,GOLGB1,ARHGEF4,LAMP1,TSC22D3,CUL1,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ZBTB18,METAP2,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SCOC,THEMIS2,DHPS,PRKAA1,AKAP17A,APBA1,HERC6,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,VASN,RPL39,TPST1,DAPK1,DLX4,ZNF117,GID8,LPGAT1,CALM1,WHSC1,NPC2,JADE2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,WDR19,ARAP1,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,SPRED1,GPR107,REPS2,CAPN12,TCTN2,DLGAP5,CCDC110,NDRG1,RALBP1,CERCAM,THRA,FTH1,BCL2L1,FLT3,EPS8L2,ZFYVE9,CD46,APOBEC3B,RALB,EPHB4,RNASEH2A,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,RAD17,ITPR3,ATP10D,ZMPSTE24,DDOST,AREL1,SLC27A3,COBL,PRKAR1A,CENPI,PBX3,CBLL1,NES,DNAH3,HLA-A,CKAP5,GOLGA2P5,FUT8,DRAM1,MSH6,TGIF1,B3GNT2,ZWINT,PAPD7,TCFL5,FBXO9,YES1,AIF1L,FOS,CDK5RAP1,CRTC2,TIMP3,FZD5,MELK,UGT8,COMMD5,SLC8B1,ERP29,MAP1LC3B,ECI1,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,CERS2,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,SH3GLB2,TDRD7,CAB39,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,ASB9,TEC,QSOX2,SPP1,B3GALNT1,FAM20C,SRP54,HLA-C,NPTN,ZRANB1,CCDC88A,TPGS2,ELK3,PDIK1L,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,JAK3,SHROOM2,COL16A1,APOL2,DRD1,CCNE2,LMO7,FAM214B,HDAC11,SOD2,OSR2,EXT2,MXD1,SAP130,CYP4F11,REEP1,ECE1,ETHE1,SEPHS1,EBAG9,UPF3A,C3orf52,CD40,TMTC2,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,SH3D19,CIT,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,CARD8,MZT2A,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,SLC35A1,RPGR,RBMS2,B3GALT6,CFAP46,NADK2,RUNX3,TCEAL8,NDRG3,FOXL1,SWAP70,RND3,CTSV,CSGALNACT1,MCUR1,PLOD3,CEP41,AHR,ABCG1,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,IL18,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,RGS12,PSMD1,PQLC2,DNAH6,CABP1,ALDH1A3,TUBG1,TINAGL1,PIK3CD,MANF,ACOX2,APOBEC3G,ERAP2,SMARCA2,VPS11,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,CYP2J2,STRN4,MERTK,RAVER2,ELF3,GNS,WDFY1,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,TUBB4B,GALNT12,WDTC1,PKP2,TESK2,PRKACA,APC2,ZNF385B,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,PXYLP1,IRS2,SIPA1L1,INPP4B,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,TMA16,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,WWP1,MAPK11,SGCB,S100A6,CRTAP,AMOTL2,MOB4,CTNNAL1,FMN1,BCL9,GRIN1,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,HMGA1,NUP37,USF2,FOXA1,MYL9,CUL4B,SUDS3,NDC80,MCCC1,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,PXMP4,TLN2,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,CDK1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,PAK2,TMEM8A,PSMA5,CYP26B1,CHSY3,MRPS33,WDR72,TCF7,IFIT3,SMN1,MAPKAPK2,COQ10A,MFSD2A,ITGA7,TMEM120A,IFI6,NIPA1,RNF146,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,CCNL1,FAM198B,LPIN3,SDF4,PER2,SRPX,PLCG2,LHX6,SRR,MINPP1,GM2A,DVL2,CTH,CPD,EVA1A,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,ANXA9,ZBTB6,LTA4H,NDST3,POMGNT2,CNEP1R1,GSDMD,MACC1,BLVRB,CRABP2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,PSMB4,PPARA,CAPNS1,TRIM35,BORA,MAPK8IP1,PRDX4,SERPINA1,ZMYND19,CDCA7L,NMI,PKD2,ACADM,SAT2,SUN1,GAA,FAM129B,TAP1,GATA3,PLA2G16,FAM101B,CENPN,NCS1,CHST2,ELMO2,RGS3,PACSIN1,KIFC2,NBPF3,AGO4,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,ITGA3,PIK3AP1,BDH1,SORL1,FADS2,QSOX1,B9D2,PTPRH,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,SERTAD2,DCK,FGD6,NR4A2,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,AIFM2,MNS1,CYHR1,ZNF75D,IFIT1,LGMN,TMBIM1,MYO5B,CDKN2AIP,SEC23A,TMEM43,CAPN6,DMTN,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,FYN,ZNF641,PPP2R5A,STAT1,PPP1CB,SLC27A1,KLF5,MLKL,HS3ST3B1,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,SLC35G2,SPR,SIX4,RND1,FAM111A,PPP1R10,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,CTNS,SERPINB5,GPER1,NCAPG2,ARSB,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,ST13,CPT2,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,DLG1,CAPG,AKR1B1,ANKRD12,RP2,ARNT2,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,STRIP2,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,NEIL1,FASTKD1,APBA2,PSMC1,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,ZNF432,CA2,FNIP1,ZNF692,KNTC1,RFX5,NCEH1,ACAD8,LRIF1,ALS2CL,DESI2,KDELR1,OXR1,AMDHD1,NUDT16,UTP14C,PAPD5,PITPNA,FBXW5,KLF7,GAS2L1,SLC25A24,IL15,PSME2,SLC2A8,GMPR,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,AP5M1,DUSP4,SNAPC2,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CYP2U1,AKNA,SGOL1,REEP4,CBX4,ANXA3,POC1B,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,MXD3,HSPA13,IQGAP3,SYPL1,SUN2,ADAM17,GCLC,NR4A1,ASPM,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,MARC1,HNRNPH2,PRCP,DHRS2,TADA2B,UBE2D2,HOXB13,GEM |
| 5.161e-26 | -58.23 | clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_renal_cell_carcinoma | 14582 | 2301 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,DPP8,FAM46C,SPSB1,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,TMX4,RHPN2,PCBP1,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,C1orf198,PSME1,CAMK1D,PJA2,PICK1,SLC9A7,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,ACAD10,NGFRAP1,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,ZFYVE16,EPCAM,CDKL5,CASC4,ARHGEF37,ANKFN1,TRPC1,ASH2L,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,MAN2A2,HPSE,KCNK1,ZNF165,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,PDE5A,KIAA1109,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,SNX30,NCKAP5,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,TLE1,SPTBN5,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,SCN3A,RNF169,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,ZNF230,ITM2C,TPCN1,TMX1,HCN3,LCA5,RAPGEF2,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,FAM212B,CLCN2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,NKD1,DHTKD1,EIF4EBP2,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,CAST,SUZ12,IQGAP1,RPS6KA1,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,OXCT1,PHF7,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ASCL5,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,ASL,PHLPP1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,FRMD6,JKAMP,FAM134A,TRMT2B,IRF2BPL,SNX13,MDM1,GALNS,BRD7,CKS1B,FAM219A,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,PLCG1,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,CCDC64B,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,DGKG,ULBP2,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,S100A5,CLMN,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,TRAF2,OSGIN2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,ITGB8,KNDC1,TMEM62,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,KIAA0040,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,PARM1,IL22RA1,VPS26A,FZD6,SH2D4A,NRP2,M6PR,CD109,CDK16,ALPP,GTF2F2,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,CAPN12,GPR107,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,TMEM170B,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,EPHB4,TSPAN1,COG2,FOXJ2,CLSTN1,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,HTR1D,ADPRHL1,SIPA1L2,RAB15,CEP78,CTTN,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,ZDHHC13,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,RUNX3,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,CUL4B,FHDC1,MCCC1,NDC80,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,HN1L,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,CTNND1,TTC9,PIEZO1,EPB41L4A,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,DNAJC10,PTK7,ADAMTS14,ZBTB6,LTA4H,NDST3,CMTM4,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PPARA,CAPNS1,TRIM35,BSDC1,MAPK8IP1,SCRN2,CD83,CDKN2AIPNL,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CHST2,NCS1,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,SEPP1,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,CASP3,LTBP1,ST13,CPT2,EPHX4,KIF2C,DNER,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,RNF113A,AMDHD1,MUM1L1,BCAR3,NUDT16,SLC6A6,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,SLC25A24,ZSWIM5,IL15,PSME2,SLC2A8,GMPR,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,POMGNT1,ZNF212,IL17RB,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 5.161e-26 | -58.23 | kidney-carcinoma-clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_renal_cell_carcinoma | 14582 | 2301 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,DPP8,FAM46C,SPSB1,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,TMX4,RHPN2,PCBP1,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,C1orf198,PSME1,CAMK1D,PJA2,PICK1,SLC9A7,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,ACAD10,NGFRAP1,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,ZFYVE16,EPCAM,CDKL5,CASC4,ARHGEF37,ANKFN1,TRPC1,ASH2L,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,MAN2A2,HPSE,KCNK1,ZNF165,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,PDE5A,KIAA1109,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,SNX30,NCKAP5,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,TLE1,SPTBN5,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,SCN3A,RNF169,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,ZNF230,ITM2C,TPCN1,TMX1,HCN3,LCA5,RAPGEF2,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,FAM212B,CLCN2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,NKD1,DHTKD1,EIF4EBP2,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,CAST,SUZ12,IQGAP1,RPS6KA1,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,OXCT1,PHF7,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ASCL5,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,ASL,PHLPP1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,FRMD6,JKAMP,FAM134A,TRMT2B,IRF2BPL,SNX13,MDM1,GALNS,BRD7,CKS1B,FAM219A,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,PLCG1,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,CCDC64B,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,DGKG,ULBP2,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,S100A5,CLMN,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,TRAF2,OSGIN2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,ITGB8,KNDC1,TMEM62,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,KIAA0040,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,PARM1,IL22RA1,VPS26A,FZD6,SH2D4A,NRP2,M6PR,CD109,CDK16,ALPP,GTF2F2,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,CAPN12,GPR107,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,TMEM170B,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,EPHB4,TSPAN1,COG2,FOXJ2,CLSTN1,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,HTR1D,ADPRHL1,SIPA1L2,RAB15,CEP78,CTTN,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,ZDHHC13,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,RUNX3,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,CUL4B,FHDC1,MCCC1,NDC80,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,HN1L,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,CTNND1,TTC9,PIEZO1,EPB41L4A,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,DNAJC10,PTK7,ADAMTS14,ZBTB6,LTA4H,NDST3,CMTM4,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PPARA,CAPNS1,TRIM35,BSDC1,MAPK8IP1,SCRN2,CD83,CDKN2AIPNL,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CHST2,NCS1,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,SEPP1,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,CASP3,LTBP1,ST13,CPT2,EPHX4,KIF2C,DNER,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,RNF113A,AMDHD1,MUM1L1,BCAR3,NUDT16,SLC6A6,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,SLC25A24,ZSWIM5,IL15,PSME2,SLC2A8,GMPR,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,POMGNT1,ZNF212,IL17RB,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.622e-25 | -57.08 | pleura | COSMIC cancer mutations | pleura | 5040 | 958 | 17775 | 2585 |
KLK10,TRIM24,AASS,AK7,TRIM5,DNAJC3,RET,SMARCAL1,CACNA2D2,XIAP,FBXO2,MMADHC,DHX8,MORF4L2,SYTL4,LACTB2,SNX9,BARD1,SPSB1,CARD10,PHF1,ZNF275,CDKN2C,TP73,DAPK2,WEE1,ZYX,AP1M2,RGS12,MUC4,PPP1R16A,ALDH1A3,KLF3,FUT1,PPP1CA,PIK3CD,RNF26,WBP4,TIAM1,APOBEC3G,NEK4,NWD1,SMARCA2,FBXL16,SH3BGRL,UXT,RNF11,PRKAR2B,LOXL2,PPP1R14C,ICMT,RNF19B,MYOM1,ARF4,LCP1,PIAS3,PLCG1,TRIM47,MID1IP1,WDR11,LIMK1,MYLK,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,HSPB1,GAB1,ANXA11,HOXC13,NXT2,GGA1,ITGA6,RAB23,ZNRF3,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,FLII,RAC2,WDFY1,FRY,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,CADPS2,USP1,USP38,ALPK1,MAPK7,MYLIP,DGKG,NUP85,PHKG2,EPHX1,UFD1L,STAT4,MYBL2,SRSF5,ELK1,TP53INP2,DPYSL4,GNA11,DCP2,RHOB,STK17A,DHX32,PTPRF,MAGED2,NCOA3,ETS2,TIMM8A,ITPR1,DGAT2,CLMN,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,CBX5,RPS6KA3,ADAMTS16,EGLN1,DMPK,ARHGAP11A,MTM1,TMSB15A,LFNG,CD82,PTTG1,APOO,RGS20,TESK2,NUF2,IL13RA1,GRK6,PRKACA,APC2,KTN1,TNFSF9,APPBP2,CCND1,MUC16,RNF220,ST5,CDH1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,SNX8,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,SYP,RAB38,DNAJB14,TANC1,SNX12,TRIM7,NFIX,IRS2,SPIN3,CCNB3,SHROOM3,TTC12,CDK19,CORO1C,SLC9A6,AXL,SIPA1L1,INPP4B,PDXK,RGS14,GEN1,ARNT,MAPK12,FARP1,TNRC6C,TAOK2,TRAF2,BIK,CTSZ,ANO9,PKN1,ETS1,IFT27,SLC25A43,ARHGEF40,TSPAN17,NFAT5,SRPX2,BEX2,PDIA4,SGPL1,CTNNBIP1,DIRAS3,ZFX,CXCL16,ANK1,PDCD10,ITGB8,IRAK1,KNDC1,KCNK5,GPC3,CALD1,TMEM62,ALG13,MCF2L,FDXR,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,RAG1,ACBD5,ADAMTS2,CTNNAL1,BCL9,RAPGEF2,DUSP23,PIK3R1,NUB1,CXorf57,PLEKHA7,UBE2A,AK4,RAB3IP,SNTB1,TXK,PITX2,BTG1,PROM1,CCDC6,NR1D2,ACVRL1,SYT7,FAM3C,PPM1H,FBXO44,CENPE,ITGAV,HMGA1,FHL1,NUP37,CD81,SRSF9,FOXA1,ILDR1,TNK1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,PDGFB,NUP62CL,PIGL,PLS3,BTG3,CPNE2,INPP5E,RPS6KA2,PCNA,NUP210,TM9SF2,CTNNB1,SHC3,CNTRL,ARL1,MKRN3,IL6ST,ELF5,DUSP10,RGS5,TNFRSF18,ANO4,SCARA3,TLN2,MYBL1,TRAM1,ZNF462,PLK1,THRB,KRT80,PCGF5,PTPN18,MARK1,CBX6,CR2,KLK6,ARFRP1,IDH1,SESN1,RHEB,PLEKHB1,VCP,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,MAP2,HOXA9,CTNND1,KLF11,KPNA2,PIK3C2B,MAFF,RRAGD,PRKAA2,RUNX2,BMF,DNAJB2,RASA2,RACGAP1,ADCK5,RAB6A,HES2,CNTNAP2,B4GALT4,RB1,DAZAP1,IGF1R,TIMP1,SPIN4,GATA2,KIF13B,PIM1,PLCB2,ALDH3A2,CHSY3,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,PDK3,BCL2L13,UNC45B,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,CCNB2,RNF146,RAD21,USP43,NF2,UPF3B,FOXM1,DGKA,TP53,ERBB2,ZNF28,P2RX7,RASGRP3,CCNL1,PCBP1,STIL,BCAP31,PER2,RAD23A,CDK14,SRPX,WDR44,TACC2,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,CLCN3,AKT1,FIGNL1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,RPL22,ARHGAP4,CMTM4,GSDMD,ZMAT1,BIN1,PINK1,DYRK3,GOLIM4,TAB3,KLHL13,MACC1,GNAL,PSMD10,GDF15,NKRF,HMGN3,JAG2,LBR,PARM1,VPS26A,PPP2R3A,NRP2,SIRPA,DNAJB9,FZD6,ZDHHC21,FOXP2,CDK16,MAGEE1,UBE2J1,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,CAMK2G,ATP2B1,WBP5,DUSP1,DLGAP1,HES1,RHOA,FBLN5,MOSPD2,HMGN5,CRIP2,LITAF,MAML2,TRIM35,AKAP3,BCAR1,DGKE,PRDX4,USP6,BCL10,DDX23,CNOT2,SERPINA1,FAT4,NEIL3,ZNF214,E2F1,PGRMC1,PPP2R3C,SH3BGRL2,PKD2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,ACVR1,LGR4,VANGL1,FAM129B,TSC22D3,PPFIBP2,GATA3,CUL1,CAMK1D,CCNB1,PICK1,SLC9A7,PAK6,ZFP36,RGS3,OSBPL3,PRICKLE3,IQCE,FOSB,PIK3CA,POLL,SNX16,TFG,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,BNIP3L,AURKB,PIF1,SAV1,CCNF,SLC25A5,TP53I3,RAB2B,ULK2,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,TBX1,SH2D3C,PPP2R4,LRIG1,NKD1,MAPK13,SERPINI1,SPRY4,TANC2,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,PRKAA1,DGKQ,KIF23,AKAP17A,NOTCH2,TNFRSF19,S100A2,TSPAN7,PSIP1,BMP2K,MECOM,RALGPS2,ITGA3,SNX18,BHLHE41,NECAB3,RPL39,PPP4R1,MSH2,DAPK1,ADCK2,PRKG1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,KCTD3,RIMS2,EEF1D,SOCS5,PIGC,DDB2,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,DCHS1,PIP4K2C,WHSC1,VEZT,KDM3A,FBXO10,NFIB,RASA1,FAS,MMP15,DGKH,PRKAG2,TMEM54,FAAH,SLC4A3,TCEAL4,PIAS2,PCDH19,CABIN1,KLK7,CDK18,MAP3K5,NRBP1,IRF1,PLEKHG3,FRMPD3,ELK4,PLA2G4A,SPRED1,SLC2A4,REPS2,CAPN12,ARMCX3,TRIP10,NDRG1,SUZ12,RPS6KA1,IRX4,FTH1,BCL2L1,CD274,FLT3,DDR1,TMPRSS4,GNB2,ZFYVE9,EPM2A,APOBEC3B,NOV,CCNA2,ZNF75D,RALB,DOK4,CDKN1B,TNPO2,EPHB4,PDE4D,PHKA2,TSPAN1,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,BCL7B,C15orf39,CBL,ITPR3,ASB13,SP4,FZD7,ZMPSTE24,CMTM7,NIN,EPHA10,FYN,PPP2R5A,JAK1,NGFRAP1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,MLKL,ZC3H12B,CBX7,PRKAR1A,OTUD5,IER5L,ARHGEF3,CENPI,ARL4C,CBLL1,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,HLA-A,SCML1,RND1,WWP2,E2F7,GNB5,RNF128,PTEN,DRAM1,SGK3,PRC1,ERCC2,ERBB3,MAP3K7,SPRY2,TRIM62,NCOA2,MSH6,SMC4,RASGRF1,TGIF1,ZWINT,ALDH2,CASK,LONRF3,MPP1,ZKSCAN2,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,FOS,KIF11,GPLD1,CDK5RAP1,CRTC2,TIMP3,RCBTB2,FGFR2,AMMECR1,CSTF2,SERPINB5,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,PLAC1,TAF6L,KIF2C,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,SIPA1L2,CDKL5,ZCCHC12,TSPAN6,CAPG,POF1B,ANKRD12,KIF22,ASH2L,RAB20,RP2,NFU1,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TRIM8,CENPA,ASXL1,USP18,ACBD3,ITCH,RGAG1,ROR1,STK17B,ADRBK2,CXXC4,ZNF114,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,GLA,RAP1GAP,PPP2R5D,NR2C2,CD99,ARAP3,PPP1R2,PPP1R12A,SERPINE2,PEX6,ETV5,ASB9,DUSP5,SPP1,PFKL,OCRL,PRKCI,SRP54,FNIP1,BRAT1,KNTC1,ZRANB1,ETV7,SNX7,ELK3,OXR1,FBXO8,KIAA1109,RNF113A,PDIK1L,RANBP9,EGFR,MUM1L1,BCAR3,XKRX,INSR,UAP1,NFKBIA,PAPD5,RAB31,ALPK3,RHOBTB2,PITPNA,SHROOM2,JAK3,TOB1,RARG,FBXW5,CCNE2,NCKAP5,PAX6,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,MXD1,SAP130,SS18,CYP4F11,FRYL,SMO,TWIST1,APIP,LOXL1,HSPA2,SCYL3,EBAG9,CKS2,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,CD40,DUSP4,CDC25C,FANCE,KCTD2,PDHX,MAP3K6,CASP4,SOCS3,HSF4,STAT6,BHLHB9,CANT1,TLE1,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,ARHGEF7,SERPINB9,TGFBR1,COL4A5,TRMT2B,TRIB2,SBF1,HMGXB4,ITGA2B,HDAC9,IL17RB,TOP2A,SNX13,CARD8,ADRBK1,LLGL2,MYCL,TOX2,TRIM3,CKS1B,MXD3,HSPA13,RPGR,MYO5A,PGM1,ADAM17,RAB3B,WNT10B,SYBU,MBNL3,RUNX3,POLD3,TCEAL8,FOXL1,KLHL2,ARHGAP24,SWAP70,CASP7,RND3,HNRNPH2,RAP2C,UBE2D2,GRAMD1C,ZMIZ1,GEM,L1CAM,AHR,RAB3IL1,ABCG1,NGEF |
| 1.666e-25 | -57.05 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 16161 | 2479 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,C17orf75,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 7.389e-25 | -55.56 | lung-carcinoma-non_small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-non_small_cell_carcinoma | 5361 | 1005 | 17775 | 2585 |
ACACB,KLK10,TRIM24,GRIK2,AK7,TRIM5,SLC25A13,DNAJC3,RET,SMARCAL1,XIAP,MMADHC,FBXO2,DHX8,LGI3,MORF4L2,SYTL4,ISOC2,LACTB2,DPP8,SNX9,BARD1,SPSB1,CARD10,PHF1,ZNF275,EPDR1,CDKN2C,TP73,DAPK2,WEE1,RGS12,PPP1R16A,ALDH1A3,KLF3,FUT1,ACOX2,PPP1CA,PIK3CD,RNF26,WBP4,TIAM1,APOBEC3G,NEK4,SMARCA2,FBXL16,SH3BGRL,UXT,RNF11,PRKAR2B,LOXL2,PPP1R14C,ICMT,ABR,ARF4,LCP1,PIAS3,PLCG1,TRIM47,MID1IP1,WDR11,ATP7B,LIMK1,MYLK,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,STARD13,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RAC2,WDFY1,PRICKLE4,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,USP1,USP38,ALPK1,MAPK7,MOXD1,DGKG,NUP85,PHKG2,UFD1L,STAT4,MYBL2,CALCRL,SRSF5,ELK1,TP53INP2,SPTLC2,GNA11,RHOB,STK17A,DHX32,PTPRF,MAGED2,NCOA3,ETS2,TIMM8A,ITPR1,DGAT2,CLMN,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,CBX5,RPS6KA3,ADAMTS16,EGLN1,DMPK,ARHGAP11A,MTM1,TMSB15A,LFNG,CD82,PTTG1,APOO,RGS20,TESK2,NUF2,IL13RA1,GRK6,FAM91A1,PRKACA,APC2,KTN1,TNFSF9,APPBP2,UHRF1BP1L,CCND1,MUC16,RNF220,ST5,CDH1,SH3BP1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,SNX8,SSH3,COL6A2,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,SYP,RAB38,DNAJB14,SNX12,TRIM7,NFIX,IRS2,SPIN3,CCNB3,CDK19,CORO1C,SLC9A6,AXL,INPP4B,DMWD,PDXK,RGS14,GEN1,ARNT,MAPK12,FARP1,TAOK2,GCAT,TRAF2,BIK,CCM2,SDC4,PDIA3,CTSZ,ANO9,PKN1,KCNC4,ETS1,IFT27,SLC25A43,ARHGEF40,TSPAN17,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,CXCL16,ANK1,PDCD10,ITGB8,IRAK1,KNDC1,KCNK5,GPC3,CALD1,MCF2L,ALG13,FDXR,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,RAG1,TPCN1,S100A6,ADAMTS2,CTNNAL1,BCL9,RAPGEF2,DUSP23,PIK3R1,NUB1,CXorf57,PLEKHA7,UBE2A,AK4,PGBD1,RAB3IP,SNTB1,TXK,PITX2,BTG1,PROM1,CCDC6,ACVRL1,NR1D2,FAM3C,PPM1H,FBXO44,CENPE,ITGAV,HMGA1,FHL1,NUP37,CD81,SRSF9,FOXA1,TMEM131,TNK1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,NUP62CL,PDGFB,PIGL,FANCI,PLS3,BTG3,INPP5E,RPS6KA2,PCNA,NUP210,CTNNB1,SHC3,CNTRL,ARL1,IL6ST,ELF5,DUSP10,RGS5,TNFRSF18,SCARA3,MYBL1,TRAM1,NEB,ZNF462,PLK1,THRB,KRT80,PCGF5,MCTP1,PTPN18,MARK1,CELSR2,CBX6,EZR,CR2,KLK6,ARFRP1,ANLN,IDH1,SESN1,CLCN2,RHEB,PLEKHB1,VCP,DZIP1L,IRX3,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,MAP2,HOXA9,CTNND1,KLF11,KPNA2,PIK3C2B,PIEZO1,MAFF,RRAGD,PRKAA2,RUNX2,BMF,HJURP,DNAJB2,ZCCHC24,RASA2,RACGAP1,ADCK5,RAB6A,HES2,CNTNAP2,RSAD1,MYO5C,RB1,IGF1R,TIMP1,SPIN4,GATA2,FRAS1,PIM1,NTN1,PLCB2,ALDH3A2,CYP26B1,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,ZSCAN12,PDK3,BCL2L13,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,SEMA3A,CCNB2,RNF146,USP43,RAD21,NF2,UPF3B,FOXM1,XYLT1,DGKA,TP53,ERBB2,P2RX7,RASGRP3,SLC7A2,CCNL1,PCBP1,STIL,BCAP31,C1orf116,RAD23A,CDK14,SRPX,WDR44,TACC2,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,FIGNL1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,RPL22,ARHGAP4,CMTM4,FAM134B,ZMAT1,BIN1,COL9A3,PINK1,DYRK3,GOLIM4,TRAPPC10,KLHL13,TAB3,SCD5,GNAL,MCTP2,PSMD10,GDF15,NKRF,HMGN3,JAG2,DSE,LBR,PPP2R3A,SIRPA,DNAJB9,FZD6,SH2D4A,ZDHHC21,FOXP2,CEP97,CDK16,MAGEE1,UBE2J1,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,SLC45A3,CAMK2G,WBP5,DUSP1,HMMR,DLGAP1,HES1,FBLN5,RHOA,MOSPD2,HMGN5,CRIP2,LITAF,MAML2,TRIM35,CAPNS1,AKAP3,BCAR1,TXNDC11,DGKE,PRDX4,BCL10,USP6,DDX23,CNOT2,SERPINA1,FAT4,NEIL3,NETO2,E2F1,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GAA,ACVR1,LGR4,HSPG2,VANGL1,TSC22D3,PPFIBP2,GATA3,CUL1,CAMK1D,CCNB1,VASH1,PICK1,SLC9A7,PAK6,CYP1A1,ANKS6,ZFP36,RGS3,OSBPL3,IQCE,PRICKLE3,FOSB,PIK3CA,POLL,SNX16,TFG,RCAN3,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,BNIP3L,NBPF3,TNS1,SLC17A5,AURKB,PIF1,LDB2,SAV1,CCNF,SLC25A5,TP53I3,RAB2B,ULK2,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,SH2D3C,PPP2R4,LRIG1,NKD1,MAPK13,SERPINI1,SPRY4,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,PRKAA1,DGKQ,CALB2,KIF23,AKAP17A,SLC1A3,NOTCH2,TNFRSF19,S100A2,TSPAN7,PSIP1,BMP2K,MECOM,DOPEY2,RALGPS2,ITGA3,SNX18,BHLHE41,SLC16A6,RPL39,PPP4R1,MSH2,DAPK1,PRKG1,ADCK2,CD70,TNFRSF12A,PIKFYVE,RIMS2,EEF1D,SOCS5,IGSF3,PIGC,DDB2,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,WHSC1,KDM3A,FBXO10,NFIB,RASA1,PDE11A,FAS,MMP15,DGKH,PRKAG2,PLEKHH2,TMEM54,TCEAL4,PIAS2,FAM83D,ARAP1,PCDH19,CDK18,KLK7,EFNA1,PER3,MAP3K5,NRBP1,IRF1,PLEKHG3,FRMPD3,ELK4,PLA2G4A,SPRED1,REPS2,CAPN12,ARMCX3,TRIP10,NLRX1,NDRG1,SUZ12,RPS6KA1,THRA,IRX4,BCL2L1,CD274,FLT3,DDR1,GNB2,ZFYVE9,EPM2A,APOBEC3B,NOV,CCNA2,ZNF75D,RALB,DOK4,CDKN1B,TNPO2,EPHB4,PDE4D,PHKA2,ATG4D,SLC5A11,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,BCL7B,C15orf39,CBL,ITPR3,ASB13,FZD7,ZMPSTE24,CMTM7,NIN,EPHA10,FYN,PPP2R5A,JAK1,NGFRAP1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,MLKL,ZC3H12B,COBL,CBX7,PRKAR1A,OTUD5,IER5L,ARHGEF3,HAPLN3,CENPI,ARL4C,CBLL1,HERC5,PLD2,FBXO6,EFNB1,FGF19,TEAD3,COX7A2,CKAP5,SCML1,RND1,WWP2,E2F7,OXCT1,GNB5,RNF128,PTEN,MGAT1,DRAM1,SGK3,ERCC2,ERBB3,MAP3K7,CNPY3,SPRY2,TRIM62,NCOA2,MSH6,SMC4,FARP2,RASGRF1,TGIF1,ZWINT,ALDH2,CASK,LONRF3,MPP1,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,LRRC1,FOS,KIF11,GPLD1,CDK5RAP1,CRTC2,TIMP3,RCBTB2,FGFR2,TBX18,AMMECR1,CSTF2,SERPINB5,CCDC69,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,PLAC1,TAF6L,KIF2C,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,SIPA1L2,CDKL5,ZCCHC12,IMPAD1,TSPAN6,CAPG,POF1B,ASH2L,RAB20,RP2,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TDP1,TRIM8,CENPA,ASXL1,USP18,ACBD3,ITCH,RGAG1,ROR1,STK17B,ADRBK2,TCN2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,GLA,RAP1GAP,CHPT1,PPP2R5D,CAPN1,NR2C2,CD99,ARAP3,PPP1R2,PPP1R12A,SERPINE2,ETV5,ASB9,DUSP5,SPP1,TYW3,AIM1L,PFKL,OCRL,PRKCI,SRP54,BRAT1,KNTC1,HLA-C,ZRANB1,ETV7,SLC12A2,CCDC88A,SNX7,HP1BP3,ELK3,OXR1,FBXO8,RNF113A,PDIK1L,RANBP9,EGFR,MUM1L1,GNAS,BCAR3,XKRX,INSR,UAP1,CDCA5,NFKBIA,PAPD5,SPAG7,RAB31,ALPK3,RHOBTB2,PITPNA,SHROOM2,JAK3,TOB1,RARG,APOL2,FBXW5,CCNE2,PAX6,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,MXD1,SS18,SMO,RPN2,TWIST1,APIP,LOXL1,HSPA2,SCYL3,EBAG9,CKS2,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,BTBD19,GLO1,ERBB2IP,CD40,DUSP4,CDC25C,FANCE,KCTD2,DOCK5,PDHX,MAP3K6,CASP4,SOCS3,STAT6,BHLHB9,PLXND1,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,ARHGEF7,FRMD6,SERPINB9,TGFBR1,COL4A5,TRMT2B,TRIB2,XPR1,HMGXB4,ITGA2B,HDAC9,KIF5B,IL17RB,TOP2A,SNX13,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,MYCL,TRIM3,CKS1B,MXD3,HSPA13,RPGR,MYO5A,PGM1,ADAM17,RAB3B,WNT10B,ASPM,SYBU,RC3H2,OGDHL,MBNL3,RUNX3,POLD3,TCEAL8,FOXL1,KLHL2,ARHGAP24,ENDOD1,SWAP70,CASP7,RND3,HNRNPH2,DHRS2,RAP2C,UBE2D2,DTX4,GRAMD1C,ZMIZ1,PLOD3,GEM,L1CAM,AHR,RAB3IL1,SNPH,NGEF,CD33 |
| 7.389e-25 | -55.56 | non_small_cell_carcinoma | COSMIC cancer mutations | non_small_cell_carcinoma | 5361 | 1005 | 17775 | 2585 |
ACACB,KLK10,TRIM24,GRIK2,AK7,TRIM5,SLC25A13,DNAJC3,RET,SMARCAL1,XIAP,MMADHC,FBXO2,DHX8,LGI3,MORF4L2,SYTL4,ISOC2,LACTB2,DPP8,SNX9,BARD1,SPSB1,CARD10,PHF1,ZNF275,EPDR1,CDKN2C,TP73,DAPK2,WEE1,RGS12,PPP1R16A,ALDH1A3,KLF3,FUT1,ACOX2,PPP1CA,PIK3CD,RNF26,WBP4,TIAM1,APOBEC3G,NEK4,SMARCA2,FBXL16,SH3BGRL,UXT,RNF11,PRKAR2B,LOXL2,PPP1R14C,ICMT,ABR,ARF4,LCP1,PIAS3,PLCG1,TRIM47,MID1IP1,WDR11,ATP7B,LIMK1,MYLK,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,ITPKA,ARF6,STARD13,HSPB1,GAB1,HOXC13,NXT2,ITGA6,RAB23,GPSM2,COX6C,MERTK,LMNA,ELF3,ATG4A,RAC2,WDFY1,PRICKLE4,FBXO7,RANBP1,NEK2,FBXL14,MAP3K9,USP1,USP38,ALPK1,MAPK7,MOXD1,DGKG,NUP85,PHKG2,UFD1L,STAT4,MYBL2,CALCRL,SRSF5,ELK1,TP53INP2,SPTLC2,GNA11,RHOB,STK17A,DHX32,PTPRF,MAGED2,NCOA3,ETS2,TIMM8A,ITPR1,DGAT2,CLMN,AURKA,MDH1,GDF11,FBXO27,DRP2,SERPINB1,CBX5,RPS6KA3,ADAMTS16,EGLN1,DMPK,ARHGAP11A,MTM1,TMSB15A,LFNG,CD82,PTTG1,APOO,RGS20,TESK2,NUF2,IL13RA1,GRK6,FAM91A1,PRKACA,APC2,KTN1,TNFSF9,APPBP2,UHRF1BP1L,CCND1,MUC16,RNF220,ST5,CDH1,SH3BP1,DACT1,ACSL4,ARL4D,RASGEF1A,RAB27B,DLG3,CDKN2D,ETV4,SNX10,SNX8,SSH3,COL6A2,RIPK2,APOBEC3D,FZD4,PTPN9,SEPT6,PLEKHO1,SAT1,SYP,RAB38,DNAJB14,SNX12,TRIM7,NFIX,IRS2,SPIN3,CCNB3,CDK19,CORO1C,SLC9A6,AXL,INPP4B,DMWD,PDXK,RGS14,GEN1,ARNT,MAPK12,FARP1,TAOK2,GCAT,TRAF2,BIK,CCM2,SDC4,PDIA3,CTSZ,ANO9,PKN1,KCNC4,ETS1,IFT27,SLC25A43,ARHGEF40,TSPAN17,SRPX2,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,CXCL16,ANK1,PDCD10,ITGB8,IRAK1,KNDC1,KCNK5,GPC3,CALD1,MCF2L,ALG13,FDXR,BAX,PLEKHF1,ADAM15,WWP1,MAPK11,NKAPP1,RAG1,TPCN1,S100A6,ADAMTS2,CTNNAL1,BCL9,RAPGEF2,DUSP23,PIK3R1,NUB1,CXorf57,PLEKHA7,UBE2A,AK4,PGBD1,RAB3IP,SNTB1,TXK,PITX2,BTG1,PROM1,CCDC6,ACVRL1,NR1D2,FAM3C,PPM1H,FBXO44,CENPE,ITGAV,HMGA1,FHL1,NUP37,CD81,SRSF9,FOXA1,TMEM131,TNK1,TRIM2,EPAS1,FAM199X,EPHA4,CUL4B,ARFGEF1,DNAJB11,ITPR2,TP53I11,HDAC6,NUP62CL,PDGFB,PIGL,FANCI,PLS3,BTG3,INPP5E,RPS6KA2,PCNA,NUP210,CTNNB1,SHC3,CNTRL,ARL1,IL6ST,ELF5,DUSP10,RGS5,TNFRSF18,SCARA3,MYBL1,TRAM1,NEB,ZNF462,PLK1,THRB,KRT80,PCGF5,MCTP1,PTPN18,MARK1,CELSR2,CBX6,EZR,CR2,KLK6,ARFRP1,ANLN,IDH1,SESN1,CLCN2,RHEB,PLEKHB1,VCP,DZIP1L,IRX3,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,MAP2,HOXA9,CTNND1,KLF11,KPNA2,PIK3C2B,PIEZO1,MAFF,RRAGD,PRKAA2,RUNX2,BMF,HJURP,DNAJB2,ZCCHC24,RASA2,RACGAP1,ADCK5,RAB6A,HES2,CNTNAP2,RSAD1,MYO5C,RB1,IGF1R,TIMP1,SPIN4,GATA2,FRAS1,PIM1,NTN1,PLCB2,ALDH3A2,CYP26B1,PLEKHA6,USP31,TESK1,PCBP3,CORO2A,SPATA13,STRADB,SCRIB,EIF2AK1,ZSCAN12,PDK3,BCL2L13,G2E3,CDK5R1,RASGRP2,FOXD2,MAPKAPK2,ITGA7,PRPS2,ZDHHC7,PLD1,SEMA3A,CCNB2,RNF146,USP43,RAD21,NF2,UPF3B,FOXM1,XYLT1,DGKA,TP53,ERBB2,P2RX7,RASGRP3,SLC7A2,CCNL1,PCBP1,STIL,BCAP31,C1orf116,RAD23A,CDK14,SRPX,WDR44,TACC2,LMO4,PLCG2,BCL6,PLK4,NOTCH3,MINPP1,EGLN3,DVL2,SULF2,SIRT1,AKT1,FIGNL1,CDC20,PTGER4,ACO1,MYL12A,PTGS2,DNAJC10,PTPRJ,RBL1,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,RPL22,ARHGAP4,CMTM4,FAM134B,ZMAT1,BIN1,COL9A3,PINK1,DYRK3,GOLIM4,TRAPPC10,KLHL13,TAB3,SCD5,GNAL,MCTP2,PSMD10,GDF15,NKRF,HMGN3,JAG2,DSE,LBR,PPP2R3A,SIRPA,DNAJB9,FZD6,SH2D4A,ZDHHC21,FOXP2,CEP97,CDK16,MAGEE1,UBE2J1,TRIM21,SGK1,BUB1,ALDH7A1,ABCD1,FAIM,SYK,SLC45A3,CAMK2G,WBP5,DUSP1,HMMR,DLGAP1,HES1,FBLN5,RHOA,MOSPD2,HMGN5,CRIP2,LITAF,MAML2,TRIM35,CAPNS1,AKAP3,BCAR1,TXNDC11,DGKE,PRDX4,BCL10,USP6,DDX23,CNOT2,SERPINA1,FAT4,NEIL3,NETO2,E2F1,PGRMC1,PPP2R3C,SH3BGRL2,UBE2C,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GAA,ACVR1,LGR4,HSPG2,VANGL1,TSC22D3,PPFIBP2,GATA3,CUL1,CAMK1D,CCNB1,VASH1,PICK1,SLC9A7,PAK6,CYP1A1,ANKS6,ZFP36,RGS3,OSBPL3,IQCE,PRICKLE3,FOSB,PIK3CA,POLL,SNX16,TFG,RCAN3,ARMCX6,SMYD5,LAMP2,ORAI2,ACVR1C,PBK,CASP9,HSPA12A,BNIP3L,NBPF3,TNS1,SLC17A5,AURKB,PIF1,LDB2,SAV1,CCNF,SLC25A5,TP53I3,RAB2B,ULK2,AHRR,KDSR,ANKRD10,FAM177A1,HLF,PLK2,SH2D3C,PPP2R4,LRIG1,NKD1,MAPK13,SERPINI1,SPRY4,UNC5B,TRAF5,F2RL1,DLAT,FGD1,DDX58,RECQL,INPPL1,CDK17,FRMD4A,CDKN1C,PRKAA1,DGKQ,CALB2,KIF23,AKAP17A,SLC1A3,NOTCH2,TNFRSF19,S100A2,TSPAN7,PSIP1,BMP2K,MECOM,DOPEY2,RALGPS2,ITGA3,SNX18,BHLHE41,SLC16A6,RPL39,PPP4R1,MSH2,DAPK1,PRKG1,ADCK2,CD70,TNFRSF12A,PIKFYVE,RIMS2,EEF1D,SOCS5,IGSF3,PIGC,DDB2,PRODH,KLK5,TBC1D8B,ADCK3,AMER1,PIP4K2C,WHSC1,KDM3A,FBXO10,NFIB,RASA1,PDE11A,FAS,MMP15,DGKH,PRKAG2,PLEKHH2,TMEM54,TCEAL4,PIAS2,FAM83D,ARAP1,PCDH19,CDK18,KLK7,EFNA1,PER3,MAP3K5,NRBP1,IRF1,PLEKHG3,FRMPD3,ELK4,PLA2G4A,SPRED1,REPS2,CAPN12,ARMCX3,TRIP10,NLRX1,NDRG1,SUZ12,RPS6KA1,THRA,IRX4,BCL2L1,CD274,FLT3,DDR1,GNB2,ZFYVE9,EPM2A,APOBEC3B,NOV,CCNA2,ZNF75D,RALB,DOK4,CDKN1B,TNPO2,EPHB4,PDE4D,PHKA2,ATG4D,SLC5A11,CAPN6,FOXJ2,PRKCQ,PKMYT1,PYGO1,BCL7B,C15orf39,CBL,ITPR3,ASB13,FZD7,ZMPSTE24,CMTM7,NIN,EPHA10,FYN,PPP2R5A,JAK1,NGFRAP1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,MLKL,ZC3H12B,COBL,CBX7,PRKAR1A,OTUD5,IER5L,ARHGEF3,HAPLN3,CENPI,ARL4C,CBLL1,HERC5,PLD2,FBXO6,EFNB1,FGF19,TEAD3,COX7A2,CKAP5,SCML1,RND1,WWP2,E2F7,OXCT1,GNB5,RNF128,PTEN,MGAT1,DRAM1,SGK3,ERCC2,ERBB3,MAP3K7,CNPY3,SPRY2,TRIM62,NCOA2,MSH6,SMC4,FARP2,RASGRF1,TGIF1,ZWINT,ALDH2,CASK,LONRF3,MPP1,FURIN,C1GALT1C1,FBXO9,DIAPH2,YES1,LRRC1,FOS,KIF11,GPLD1,CDK5RAP1,CRTC2,TIMP3,RCBTB2,FGFR2,TBX18,AMMECR1,CSTF2,SERPINB5,CCDC69,FZD5,NCAPG2,ESPL1,CXorf56,MELK,DEF6,USP16,JARID2,LTBP1,CASP3,ST13,CAMKK1,UBE2Q1,PLAC1,TAF6L,KIF2C,KREMEN1,DENND2D,SH3KBP1,ABCD4,ARHGEF10L,RAB15,SIPA1L2,CDKL5,ZCCHC12,IMPAD1,TSPAN6,CAPG,POF1B,ASH2L,RAB20,RP2,CTTN,PTPRE,STK35,RASGRP1,NLRP4,TDP1,TRIM8,CENPA,ASXL1,USP18,ACBD3,ITCH,RGAG1,ROR1,STK17B,ADRBK2,TCN2,CXXC4,ARHGEF19,NEIL1,HPSE,UEVLD,MADD,TRIM45,CAB39,GLA,RAP1GAP,CHPT1,PPP2R5D,CAPN1,NR2C2,CD99,ARAP3,PPP1R2,PPP1R12A,SERPINE2,ETV5,ASB9,DUSP5,SPP1,TYW3,AIM1L,PFKL,OCRL,PRKCI,SRP54,BRAT1,KNTC1,HLA-C,ZRANB1,ETV7,SLC12A2,CCDC88A,SNX7,HP1BP3,ELK3,OXR1,FBXO8,RNF113A,PDIK1L,RANBP9,EGFR,MUM1L1,GNAS,BCAR3,XKRX,INSR,UAP1,CDCA5,NFKBIA,PAPD5,SPAG7,RAB31,ALPK3,RHOBTB2,PITPNA,SHROOM2,JAK3,TOB1,RARG,APOL2,FBXW5,CCNE2,PAX6,SPC25,HDAC11,MORC4,MRAS,ARHGEF16,MXD1,SS18,SMO,RPN2,TWIST1,APIP,LOXL1,HSPA2,SCYL3,EBAG9,CKS2,SUSD3,MAP3K3,BAG4,KREMEN2,PTPRU,BTBD19,GLO1,ERBB2IP,CD40,DUSP4,CDC25C,FANCE,KCTD2,DOCK5,PDHX,MAP3K6,CASP4,SOCS3,STAT6,BHLHB9,PLXND1,PPP2R2D,LIFR,CBX4,CDS2,ENO2,ARHGEF11,ARHGEF7,FRMD6,SERPINB9,TGFBR1,COL4A5,TRMT2B,TRIB2,XPR1,HMGXB4,ITGA2B,HDAC9,KIF5B,IL17RB,TOP2A,SNX13,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,MYCL,TRIM3,CKS1B,MXD3,HSPA13,RPGR,MYO5A,PGM1,ADAM17,RAB3B,WNT10B,ASPM,SYBU,RC3H2,OGDHL,MBNL3,RUNX3,POLD3,TCEAL8,FOXL1,KLHL2,ARHGAP24,ENDOD1,SWAP70,CASP7,RND3,HNRNPH2,DHRS2,RAP2C,UBE2D2,DTX4,GRAMD1C,ZMIZ1,PLOD3,GEM,L1CAM,AHR,RAB3IL1,SNPH,NGEF,CD33 |
| 7.754e-25 | -55.52 | intracellular | cellular component | GO:0005622 | 13688 | 2201 | 17570 | 2579 |
HECA,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,SPSB1,GRM5,UBE2T,ATP13A3,DNM2,PPP1CA,CPE,DNAAF3,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,LCP1,ABR,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,SEC61G,MTL5,RAB23,GPSM2,FAM21C,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,PPP6R1,MCCC2,REC8,PYM1,FHL2,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,PLIN5,ETS2,DGAT2,GDF11,TMEM173,DMPK,C5orf30,MAPK4,MGST2,RBM23,MUC16,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,SEPT6,PTPN9,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,GTF2A2,SNX12,TRIM7,ZNF618,NFIX,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,SLC25A30,CTHRC1,HSP90B1,CKAP2,BACE1,DCAF7,ESRP1,CCM2,BIK,SDC4,HABP4,FLOT1,CTSZ,ZNF219,HDGFRP2,NFAT5,BEX2,DIRAS3,GPC3,MGAT4A,TUBGCP6,KLC3,BAX,IGFBP2,MED22,ACBD5,TACC1,PIK3R1,DUSP23,MRS2,NUB1,PGBD1,RAB3IP,PIM3,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,WDR45B,SRSF9,ACOT7,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,INPP5E,BTG3,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,ARFRP1,DZIP1L,TRIM9,PI4K2B,HOXA9,ARRDC1,KLF11,RUNX2,LMTK3,PARP12,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,KIF13B,TBCD,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,NTN1,DPYSL5,USP31,EMC2,STRADB,ZSCAN12,PDK3,PRX,CDK5R1,COL13A1,PHLPP2,KBTBD2,NLRC5,PLD1,AKIP1,CCNB2,CDAN1,USP43,HOXB7,RHPN2,PCBP1,BCAP31,IER3,KMT5C,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,CFAP36,ATP13A2,ZNF628,IDE,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ARFGEF3,ZMAT1,PINK1,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,UBE2J1,ALDH7A1,CPLX1,ATP2B1,GCNT1,DUSP1,NFE2L3,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,HELZ2,TYMP,ANKS6,OSBPL3,PALD1,FOSB,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,SH2D3C,BMP1,NFKBIZ,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,BHLHE41,PPP4R1,MSH2,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,PLEKHH2,TJP3,AGBL5,PIAS2,APPL2,SFMBT1,KLK7,SAMD8,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,PDE4D,OSBPL7,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,MSANTD4,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,PYGO1,PKMYT1,ASB13,CBL,B3GALNT2,TRIQK,CEP162,ACAD10,NGFRAP1,TRIOBP,CBX7,MAMDC2,IGFBP6,DEPDC1,EPS8,HERC5,PLD2,FBXO6,SPDL1,FGF19,EFNB1,COX7A2,WWP2,SCML1,SLC25A36,E2F7,RNF128,GNB5,CD9,CITED2,TTPA,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,CPTP,DCTN6,ACADSB,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,ESPL1,DEF6,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,ZFYVE16,HSF2,CASC4,ARHGEF37,METTL7A,CDKL5,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,SUCO,PRKCI,BRAT1,GAD1,ETV7,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,STEAP1,RANBP9,SOX13,UAP1,SPAG7,RAB31,DCUN1D1,CTSA,TOB1,AFAP1,RARG,SNX30,NBPF1,LZTFL1,DYNLRB1,SORBS1,PAX6,PDIA5,COL18A1,MRAS,SAYSD1,PHLDA1,ZNF687,COX14,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CHP1,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ARHGEF7,TGFBR1,NTAN1,SBF1,XPR1,TMEM63A,KIF5B,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,DCAF6,RC3H2,SYBU,RGCC,LEMD2,ARHGAP24,CTSL,CASP7,TRIM69,SPINT2,RAP2C,DTX4,UACA,ARRB1,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,NRG2,CNTROB,MORF4L2,SYTL4,BARD1,PHF1,DAPK2,ZYX,AP1M2,TGFBR3,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,ILK,DCP2,CYB5A,STK17A,DHX32,NAAA,NCOA3,MTFMT,HTT,SETD3,TEX30,ITPR1,AURKA,GSKIP,ALG2,B4GAT1,MAL2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,NUF2,KTN1,CDS1,CCND1,SCNN1A,RNF220,ACSL4,RAB27B,CDKN2D,TMEM9,RNF169,SCN3A,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TNRC6C,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,DTX3L,CAPN2,ADD3,ARSG,FAM160A2,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,POU6F1,LCA5,NUDT8,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,DCAF10,PITX2,CCDC6,ATXN7L3,NR1D2,ARFGAP3,FHL1,SHOX2,UNKL,UNC93B1,TRIM2,AGRN,GNPDA1,EPHA4,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,UBASH3B,ASAH1,DOCK11,PGAP1,GATA2,CMTR2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,KCNAB3,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,CYP26A1,C1orf116,CDK14,RAD23A,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,ATP1A1,PSMD3,RPL22,AIFM3,ZNF701,COPG1,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,ADGRG1,RUSC2,GNE,SWI5,PSMD10,NKRF,PPP2R3A,MTRNR2L1,CEP97,BUB1,HEXIM2,FAIM,CAMK2G,MLEC,IFITM3,NR3C1,AMFR,LITAF,CARD19,FXR2,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,TMEM50B,NAT1,ZNF214,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,CFAP74,PPP4R4,ATP8A1,KLC2,PLXNA1,CCNB1,RIC1,SESN3,CTGF,ZFP36,IL31RA,STEAP2,AOX1,RCAN3,TFG,LAMP2,LOC81691,SNTB2,PBK,CASP9,TNS1,PIF1,GALNT7,SLC17A5,CCNF,SFXN1,KDSR,HLF,RBM47,PLK2,TBX1,NKD1,SARAF,DHTKD1,EIF4EBP2,TMEM8B,TRAF5,LZTS1,DLAT,KLF2,MRPL44,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,ZNF84,AMER1,PIP4K2C,CYFIP2,KDM3A,RASA1,FAS,PRKAG2,CSNK1G1,NAB2,TCEAL4,NRBP1,IRF1,PLA2G4A,FRMPD3,ELK4,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,RNF182,EGR3,SNN,NUDT12,GNB2,SLC25A35,APLP2,DOK4,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,JAK1,CFAP45,STK26,KIAA1804,NRG1,RAB29,B4GALT3,ATMIN,OTUD5,NUDT6,ARHGEF3,ANKRD13D,ARL4C,CDCA3,APOBEC3H,TEAD3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,PRC1,SGK3,ATP8B1,ERCC2,CNOT6L,CNPY3,PCCB,SHMT1,CASK,DENND1B,MPP1,TEF,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,SLC25A40,CSTF2,PGM2L1,ETAA1,SLC25A38,CPEB2,OCLN,CAMKK1,HEBP1,UBE2Z,TAF6L,CACNB4,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,PHTF1,KIF22,SUN3,RAB20,NFU1,MYH14,PTPRE,TRIM8,ASCL5,SYNE3,ROR1,TCN2,EDNRA,MDK,CXXC4,ZNF114,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,PIFO,PEX6,ASL,PHLPP1,EBF4,HP1BP3,GYLTL1B,HMG20B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,PLPP3,NFKBIA,CDCA5,RHOBTB2,ALPK3,KIF12,PROM2,SPC25,TDRKH,ZMYND10,ARHGEF16,SLC25A48,SS18,ZDHHC12,FRYL,SMO,GOT1,STEAP3,RPN2,APIP,F2R,LOXL1,SCYL3,FRS3,MAP3K3,GCA,ZNF525,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,JKAMP,FRMD6,ARMC7,TRMT2B,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,CENPC,MBNL3,OGDHL,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,ZNF596,SNPH,IBTK,AK7,GRIK2,SLC25A13,RET,TRAPPC8,LACTB2,ISOC2,SNX9,CARD10,ZNF275,CDKN2C,NPM2,NAPG,MUC4,CRY2,WBP4,TIPARP,TIAM1,MGAT5,DSTN,TMEM98,CDA,PRKAR2B,RNF19B,GINS4,ARF4,PLCG1,CARHSP1,ENPP1,ATP7B,CELF5,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,ATP5H,RANBP1,FBXO7,PCYOX1,CADPS2,SLAIN2,MYDGF,FAM84B,ZMYM1,MYLIP,DGKG,PHKG2,HPS3,PQLC3,MAPKAPK3,SHARPIN,ERO1A,KIF20B,SFXN5,GNA11,PSMA4,IL1R1,FNTA,APMAP,S100A5,CLMN,STK39,CFAP20,CBX5,NUP58,RUSC1,DOCK9,NQO1,LFNG,INPP5D,PTTG1,APOO,MVB12B,MOCS1,APPBP2,RCN1,CDH1,SH3BP1,XYLT2,RASGEF1A,DLG3,ETV4,SNX10,MX1,COL6A2,SEC61B,PFKFB2,SAT1,EBF2,COX20,GABARAPL1,ALDH3B1,CCNB3,PNPLA6,ISOC1,MAPK12,MZT1,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,SLC25A45,ZFX,PDCD10,FUT2,KNDC1,CST3,FAM20B,RAG1,PARP9,OPLAH,PLSCR1,UBE2A,AK4,C4orf27,RGPD5,RPL12,PROM1,LDLRAP1,PLOD2,DBI,NR4A3,PPM1H,SSNA1,ITGAV,OSR1,CMPK2,PHC1,ILDR1,LMCD1,DNAJB11,GALM,ITPR2,SPTB,FANCI,TFAP2E,CPNE2,CTNNB1,TM9SF2,NPNT,ARL1,PASK,MITF,SLC44A1,PSMC2,PAPSS1,SCARA3,KRT80,THRB,PLK1,KCNIP3,CELSR2,CKAP2L,CCBL2,EAF2,SESN1,KDM4D,TNS4,PLEKHG6,HS6ST1,KLF12,AGPAT2,ZNF367,KPNA2,MYL12B,TC2N,RRAGD,HJURP,LGALS3,DNAJB2,PDCL,ADCK5,SORBS3,HES2,RAB6A,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FOXD2,FA2H,P4HA3,ZDHHC7,FAM213A,RAD21,CTDSPL,TP53,P2RX7,BAHD1,EMP2,STIL,SYTL2,TMSB15B,PDGFA,TTC21B,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,STK38,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,LBR,AIP,SH2D4A,FZD6,PARM1,VPS26A,M6PR,TBC1D31,CDK16,TFAP2A,FAM63A,GTF2F2,TRIM21,SGK1,HMGCL,SYK,WBP5,P2RX4,HES1,HMGN5,GUSB,PLAUR,CRIP2,STMN3,PRICKLE1,MAML2,BBS2,RNPEP,TXNDC11,DGKE,USP6,BCL10,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ARHGEF9,GOLGB1,ARHGEF4,LAMP1,TSC22D3,CUL1,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ZBTB18,METAP2,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SCOC,THEMIS2,DHPS,PRKAA1,AKAP17A,APBA1,HERC6,TNFRSF19,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,VASN,RPL39,TPST1,DAPK1,DLX4,ZNF117,GID8,LPGAT1,CALM1,WHSC1,NPC2,JADE2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,WDR19,ZDHHC20,ARAP1,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,SPRED1,GPR107,REPS2,CAPN12,TCTN2,DLGAP5,THRA,CCDC110,NDRG1,CERCAM,RALBP1,FTH1,BCL2L1,FLT3,EPS8L2,ZFYVE9,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,RAD17,ITPR3,ATP10D,ZMPSTE24,DDOST,SLC27A3,AREL1,COBL,PRKAR1A,CENPI,PBX3,CBLL1,NES,DNAH3,HLA-A,CKAP5,GOLGA2P5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,PAPD7,TCFL5,FBXO9,YES1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,FZD5,MELK,UGT8,COMMD5,SLC8B1,ERP29,MAP1LC3B,ECI1,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,CERS2,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,ASB9,TEC,QSOX2,SPP1,B3GALNT1,FAM20C,SRP54,NPTN,HLA-C,ZRANB1,CCDC88A,TPGS2,ELK3,PDIK1L,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,FAM214B,HDAC11,SOD2,OSR2,EXT2,MXD1,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,C3orf52,CD40,TMTC2,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,SH3D19,SHPRH,CIT,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,SYDE2,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,SLC35A1,RPGR,RBMS2,B3GALT6,CFAP46,NADK2,RUNX3,TCEAL8,NDRG3,FOXL1,SWAP70,RND3,CTSV,CSGALNACT1,MCUR1,PLOD3,CEP41,AHR,ABCG1,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,IL18,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,RGS12,PSMD1,PQLC2,DNAH6,CABP1,ALDH1A3,TUBG1,TINAGL1,PIK3CD,MANF,ACOX2,APOBEC3G,ERAP2,SMARCA2,VPS11,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,CYP2J2,STRN4,MERTK,RAVER2,ELF3,GNS,WDFY1,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,TUBB4B,GALNT12,WDTC1,PKP2,TESK2,PRKACA,APC2,ZNF385B,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,PXYLP1,IRS2,SIPA1L1,INPP4B,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,TMA16,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,WWP1,MAPK11,SGCB,S100A6,CRTAP,AMOTL2,MOB4,CTNNAL1,FMN1,BCL9,GRIN1,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,MYL9,CUL4B,SUDS3,NDC80,MCCC1,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,PXMP4,TLN2,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,CDK1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,PAK2,TMEM8A,PSMA5,CYP26B1,CHSY3,MRPS33,WDR72,TCF7,IFIT3,SMN1,MAPKAPK2,COQ10A,MFSD2A,ITGA7,LTBP2,TMEM120A,IFI6,NIPA1,RNF146,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,CCNL1,FAM198B,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,GM2A,DVL2,CTH,CPD,EVA1A,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,ANXA9,ZBTB6,LTA4H,POMGNT2,NDST3,CNEP1R1,GSDMD,MACC1,BLVRB,CRABP2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,PSMB4,PPARA,CAPNS1,TRIM35,BORA,MAPK8IP1,PRDX4,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,PKD2,ACADM,SAT2,SUN1,GAA,FAM129B,TAP1,PPFIBP2,GATA3,PLA2G16,FAM101B,CENPN,NCS1,CHST2,ELMO2,RGS3,PACSIN1,KIFC2,NBPF3,AGO4,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,ITGA3,PIK3AP1,BDH1,SORL1,RIMS2,FADS2,QSOX1,B9D2,PTPRH,ANO6,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,SERTAD2,DCK,FGD6,NR4A2,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,IRX4,AIFM2,MNS1,CYHR1,ZNF75D,IFIT1,LGMN,TMBIM1,MYO5B,CDKN2AIP,SEC23A,TMEM43,CAPN6,DMTN,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,FYN,ZNF641,PPP2R5A,STAT1,PPP1CB,SLC27A1,KLF5,MLKL,HS3ST3B1,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,SLC35G2,SPR,SIX4,RND1,FAM111A,PPP1R10,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,CTNS,SERPINB5,GRIN2D,GPER1,ARSB,NCAPG2,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,ST13,CPT2,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,DLG1,CAPG,AKR1B1,ANKRD12,RP2,ARNT2,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,STRIP2,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,NEIL1,FASTKD1,APBA2,PSMC1,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,ZNF432,CA2,FNIP1,ZNF692,KNTC1,RFX5,NCEH1,ACAD8,LRIF1,ALS2CL,DESI2,KDELR1,OXR1,AMDHD1,BCAR3,NUDT16,UTP14C,PAPD5,PITPNA,FBXW5,KLF7,GAS2L1,SLC25A24,IL15,PSME2,SLC2A8,GMPR,MORC4,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,AP5M1,DUSP4,SNAPC2,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CYP2U1,AKNA,SGOL1,REEP4,CBX4,ANXA3,POC1B,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,MXD3,HSPA13,IQGAP3,SYPL1,SUN2,ADAM17,GCLC,NR4A1,DEPDC4,ASPM,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,MARC1,HNRNPH2,PRCP,DHRS2,TADA2B,UBE2D2,HOXB13,GEM |
| 1.395e-24 | -54.93 | GGGCGGR_V$SP1_Q6 | MSigDB lists | GGGCGGR_V$SP1_Q6 | 2787 | 588 | 17758 | 2588 |
TRIM24,ADD1,SLC25A13,PNPLA2,XIAP,NRG2,TRAPPC8,CNTROB,MORF4L2,DPP8,PHF1,CALM2,CDKN2C,DAPK2,WEE1,PQLC2,PSMD1,RGS12,SLC46A1,FUT1,DNM2,CLDN4,CRY2,TINAGL1,PPP1CA,WBP4,SMARCA2,RNF11,TFAP2C,RNF19B,PNKD,GINS4,COL12A1,ABR,PIAS3,CAMK2N2,DNM1L,FAM114A1,MAP3K11,HDAC1,AGFG2,MRPS28,HSPB1,PDPR,HOXC13,NXT2,GGA1,SEC61G,ITGA6,SOX9,HPCAL4,RABGGTA,TFAP4,FLII,SH3D21,PRICKLE4,FAM13B,RANBP1,FBXL14,USP1,STT3B,NCAM1,ZMYM1,MAPK7,MYLIP,KANK3,C9orf72,SHARPIN,KIF20B,ELK1,TP53INP2,SPTLC2,PSMA4,MAGED2,FNTA,MTFMT,OSMR,FBXO27,CBX5,RPS6KA3,RUSC1,GRHL2,WDTC1,ETNK1,RGS20,IL13RA1,GRK6,PRKACA,REPS1,KTN1,APPBP2,RNF220,SH3BP1,XYLT2,TAX1BP3,RASGEF1A,DLG3,ETV4,PFKFB2,FZD4,VPS4B,NUSAP1,GABARAPL1,IRS2,PEX5,SLC9A6,AXL,CORO1C,PRIMA1,RBM24,MAN1A2,DCAF7,HABP4,FLOT1,PDIA3,NUCB2,GSTP1,TIPRL,TSPAN17,NFAT5,ZFX,PDCD10,ITGB8,KCNK5,GPC3,WWP1,TPCN1,CRTAP,ACBD5,ADAMTS2,NUB1,UBE2A,EMP3,RAB3IP,SKA1,DCAF10,PITX2,CNTNAP1,BTG1,RPL12,CCDC6,PLA2G15,NR4A3,ARFGAP3,HMGA1,OSR1,TLL2,CCNI,SIGIRR,TNK1,ARFGEF1,NDRG2,PHOSPHO1,TEX2,ITPR2,MGAT5B,TP53I11,CDIPT,HDAC6,SDC1,PDGFB,SPTB,TFAP2E,PLS3,SUSD2,RABEP2,LMAN2L,IL6ST,ARL1,PASK,MITF,ABCA2,PLK1,CD55,CITED4,CBX6,NFE2L1,CKAP2L,EAF2,ESYT1,PRKRA,ANLN,IDH1,SESN1,CLCN2,CDK1,PLEKHB1,OPTN,KDM4D,IRX3,TBC1D17,AGPAT2,WIPI1,ZNF367,HOXA9,KLF11,MAFF,HS6ST3,RMND5A,DNAJB2,ZCCHC24,RAB6A,SSX2IP,BMP2,DAZAP1,VASP,IGF1R,TIMP1,ICAM5,PAK2,TBCD,AHCY,SELK,MDFIC,PIM1,NTN1,PSMA5,CYP26B1,MRPS33,MGAT4B,TCF7,SCRIB,EIF2AK1,BCL2L13,CDK5R1,FOXD2,RASGRP2,MOSPD3,PVRL2,H1F0,PRPS2,SLC2A6,ZDHHC7,KCNAB3,UPF3B,HOXB7,NF2,UGP2,TP53,DGKA,BAHD1,PRR7,BCAP31,IER3,ATP6V0B,WDR44,LMO4,SRR,PLK4,BCL6,CDH3,GLB1L2,LMAN1,DVL2,CPD,SERTAD3,ATP13A2,DUOX1,PAFAH1B3,C19orf66,MAOA,EFNA5,XRCC3,C1orf43,RPL22,CTDSP1,COL9A3,PACSIN2,CPEB4,BLVRB,JAG2,AIP,NRP2,IL22RA1,SIRPA,GBX2,CDK16,SGK1,IL17RA,ABCD1,TSPAN13,ALDH7A1,HEXIM2,DUSP1,RHOA,CRB3,PPARA,STMN3,PRICKLE1,CAPNS1,COL7A1,PELI3,FXR2,NPDC1,NEIL3,E2F1,PGRMC1,FAM117A,PPP2R3C,NDFIP1,DIS3L,TXN,PPP4R4,TSC22D3,GATA3,OAT,CENPN,SLC9A7,PICK1,PAK6,SESN3,ELMO2,STIM1,PRICKLE3,OSBPL3,ZFP36,FOSB,KCNS3,ATRNL1,IQCD,XKR8,LAMP2,SNTB2,ZFAND5,SLC25A5,RAB2B,SH2D3C,TBX1,PLK2,PTER,SERPINI1,TMEM8B,UNC5B,RTN3,FGD1,INPPL1,CDK17,ADO,PSIP1,PDXDC1,CALR,ITGA3,LYPD3,BHLHE41,BDH1,RUNDC3B,TNFRSF12A,CACNA1D,PIKFYVE,DLX4,TMED2,DNAI1,EPB41L5,SPATA20,DDB2,KIAA1841,B9D2,PTPRH,CALM1,ATP8B3,NPC2,KDM3A,NFIB,RASA1,GABRD,TMEM54,NAB2,C1orf21,AGBL5,MPP2,ARAP1,SAMD8,PER3,ARMCX3,CEP70,REPS2,TRIP10,IQGAP1,THRA,EGR3,BCL2L1,GNB2,C11orf84,APLP2,ACAP2,RALB,TNPO2,CDKN1B,FLOT2,SEMA3B,GPX4,DOCK4,TMEM43,DRAP1,KIF1C,SLC11A2,ATP1B1,RAD17,CBL,H2AFV,ALCAM,SP4,FZD7,PPP2R5A,DDOST,SLC27A1,KLF5,HS3ST3B1,SLC27A3,NR3C2,MAMDC2,OTUD5,IER5L,PCOLCE,SLC41A1,CDCA3,CBLL1,GPR180,EFNB1,FGF19,SIX4,TEAD3,AKIRIN1,RNF128,FUT8,CD9,SGK3,PRC1,TAGLN2,ERBB3,MAP3K7,CITED2,CNPY3,TRIM62,NCOA2,SMC4,ALDH2,CASK,SHMT1,LONRF3,TEF,C1GALT1C1,UBAC1,TIMP3,DGCR2,ACADSB,SEC14L4,AMMECR1,ETAA1,FZD5,DEF6,MELK,EXPH5,FAF2,TMEM184B,CPT2,FLYWCH2,CAMKK1,UBE2Z,MPP5,KIF2C,TAF6L,TSEN34,SH3KBP1,CHPF,ZFYVE16,NKAIN3,CDKL5,DPYSL2,SIVA1,PHTF1,TRPC1,MYH14,BTBD3,FGFR1OP2,ATL1,CXXC5,TRIM8,RGAG1,MAN2A2,ARHGEF19,SH3GLB2,GLA,NRGN,PPP2R5D,PCSK5,STARD3NL,LASP1,LRRFIP2,PPP1R12A,ETV5,ASL,CALM3,PHLPP1,DUSP5,KCNN4,PRKCI,MTMR10,SRP54,NPTN,GAD1,SLC12A2,CCDC88A,ELK3,OXR1,GYLTL1B,PDE5A,HMG20B,PRRC1,PDIK1L,C3orf58,XKRX,ONECUT1,INSR,NFKBIA,SPAG7,RAB31,NXPH4,RARG,KLF7,DRD1,TDRKH,SAP130,ZNF687,KCTD15,ARTN,REEP1,SMO,STEAP3,NFKB2,ETHE1,PDIA6,SCYL3,FRS3,EBAG9,SUSD3,MAP3K3,TAF5,BAG4,KREMEN2,MRPS35,GLO1,SNAPC2,CD40,MAP3K6,HSF4,OVOL1,REEP4,ABCA1,ENO2,JKAMP,CIT,SHPRH,COL4A5,NOTUM,TRIB2,XPR1,ZNF212,IRF2BPL,TOP2A,MDM1,MLPH,LLGL2,BMP7,TOX2,RRBP1,GALNS,ARVCF,CKS1B,KANK2,MXD3,C12orf75,B3GALT6,SUN2,ADAM17,DEPDC4,NR4A1,OGDHL,LEPR,MAP1B,LEMD2,SWAP70,HNRNPH2,PRCP,RAP2C,FIBCD1,CEP41,AHR |
| 4.486e-24 | -53.76 | NUYTTEN_NIPP1_TARGETS_DN | MSigDB lists | NUYTTEN_NIPP1_TARGETS_DN | 808 | 226 | 17758 | 2588 |
EXPH5,CASP3,SLC35D2,TRIM2,FAF2,TMEM184B,EPAS1,TMEM41B,PNPLA2,XIAP,TGOLN2,PJA2,SLC20A1,PDGFB,SDC1,FAM46C,ELMOD2,CMTM6,EPCAM,CDKN2C,ZYX,BTG3,NUP210,ENTPD4,P4HB,DPYSL2,OSBPL3,IL6ST,ARL1,PHTF1,ALDH1A3,SLC44A1,ATP13A3,SERINC2,RCAN3,BTBD3,TUBA4A,CYP1B1,LAMP2,ORAI2,SMARCA2,TRIM8,CXXC5,SNTB2,DSTN,CASP9,RNF11,TNFAIP8L1,ROR1,GALNT7,MCFD2,ANLN,SESN1,ARF4,SGPP1,MDK,KDSR,SFXN1,TNS4,MID1IP1,SLC25A4,HPSE,GPRC5B,KCNK1,ZNF367,FAM114A1,DHTKD1,MAPK13,KLF11,SPRY4,ITPKA,CHPT1,MAFF,E2F8,STARD3NL,FAM89A,KLF2,CDKN1C,SCOC,PDCL,SLC36A4,SORBS3,ISYNA1,DOCK11,DHRS3,DUSP5,TTYH3,ANO1,BMP2K,SSX2IP,ELF3,RAC2,UBE2Q2,ITGA3,KCNN4,VASN,PAK2,LIMCH1,SLAIN2,FAM84B,NCEH1,ZRANB1,SLC12A2,GPR161,EPHX1,QSOX1,WDR72,KIF20A,LPGAT1,ANO6,TMEM133,KCTD20,WHSC1,SPTLC2,PDIK1L,ANTXR1,C3orf58,RANBP9,GNA11,DCP2,NMT2,GNAS,EPN3,HTT,PRPS2,AURKA,STK39,SHROOM2,TMEM173,SLC25A24,NF2,GPR107,GRHL2,FOXM1,TUBB4B,CAST,RALBP1,ATP2C2,GRK6,DDR1,PHLDA1,KTN1,ARHGEF16,SDF4,MXD1,CDS1,RCN1,CCND1,STEAP3,APIP,EPB41L4B,F2R,SNX10,ETV4,MED30,SUSD3,SEC23A,TMTC1,KREMEN2,FZD4,NRBF2,SYNE2,IGSF8,H2AFV,DAG1,ZMPSTE24,OSBPL2,ALDH5A1,SLC9A6,PPP1CB,VSIG10,KLF5,PLXND1,PDXK,REEP4,ST3GAL1,ARNT,PRR15,ABCA1,CMTM4,PRKAR1A,IER5L,ANXA3,CTHRC1,PACSIN2,PINK1,IGFBP6,SLC16A14,TAB3,GCAT,BIK,AES,CTSZ,LBR,SIX4,VPS26A,GBX2,CEP97,PDCD10,GNB5,H2AFY,FAIM,SGCB,SYK,CRTAP,HMMR,NUDT8,TACC1,AMFR,PRICKLE1,AIF1L,ARSK,GALNT3,PRDX3,NR1D2,AMMECR1,SPINT2,RAP2C,PKD2,HOXB13,CEP41,PTGES,FOXA1,ESYT2,NGEF,ABCG1 |
| 3.363e-23 | -51.75 | endomembrane system | cellular component | GO:0012505 | 3658 | 731 | 17570 | 2579 |
ACACB,KLK10,IL15RA,MRPS15,TRIM5,PNPLA2,DNAJC3,HEXB,RET,FBXO2,TRAPPC8,TGOLN2,SYTL4,SNX9,TP73,AP1M2,MUC4,CABP1,CYP2S1,RDH14,FUT1,DNM2,TUBG1,CPE,MGAT5,ERAP2,SPEF2,VPS11,RNF11,TMEM98,KDELR3,ICMT,CYP4F3,ARF4,COL12A1,DNM1L,ATP7B,ARF6,ANXA11,SCN5A,FAM169A,NFKBIE,GGA1,SEC61G,CYP2J2,RAB23,FAM21C,LMNA,MARCH8,RAC2,WDFY1,FLRT3,RANBP1,FBXL14,STT3B,MYDGF,NCAM1,MOXD1,NUP85,C9orf72,PPP6R1,EPHX1,NAGPA,UFD1L,PQLC3,KIF20A,ERO1A,CALCRL,MEST,SPTLC2,GOLT1A,RHOB,CYB5A,HTT,APMAP,ITPR1,DGAT2,DYSF,B4GAT1,MAL2,ALG2,ARPC2,CBX5,NUP58,TMEM173,RUSC1,XDH,DOCK9,DMPK,MTM1,LFNG,GALNT12,APOO,RGS20,MGST2,MVB12B,PRKACA,APC2,REPS1,KTN1,CDS1,RCN1,MUC16,CDH1,XYLT2,ACSL4,RAB27B,SNX10,TMEM9,MX1,SNX8,SEC61B,ERMP1,COL6A2,SYNE2,VPS4B,HTATIP2,PXYLP1,DNAJB14,RAB38,SNX12,GABARAPL1,STX10,WFS1,SLC9A6,PNPLA6,HSP90B1,MAN1A2,BACE1,TRAF2,BIK,SDC4,FLOT1,PDIA3,GMCL1,CTSZ,PKN1,NUCB2,PDIA4,SGPL1,NEO1,CAPN2,ANK1,PDCD10,FUT2,IRAK1,CTSC,ARSG,GPC3,ALG13,MGAT4A,FAM20B,CST3,BAX,PLEKHF1,ADAM15,TMBIM6,ITM2C,TPCN1,S100A6,TMX1,CRTAP,MOB4,AMOTL2,PLSCR1,BCL9,RAPGEF2,PIK3R1,ELOVL3,EIF5A2,GRIN1,FAM109A,NEURL1B,CRISPLD2,GALNT3,LDLRAP1,PROM1,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,FAM3C,ARFGAP3,NUP37,UNC93B1,AGRN,EPHA4,ARFGEF1,NDRG2,DNAJB11,NENF,ITPR2,MGAT5B,CDIPT,PDGFB,NUP62CL,SDC1,PIGL,SLC9A3R2,INPP5E,ENTPD4,NUP210,RPS6KA2,TM9SF2,RABEP2,P4HB,ARL1,LMAN2L,DDHD2,PASK,ABCA2,DUSP10,SCARA3,TRAM1,KCNIP3,STAU2,NFE2L1,EZR,ERP44,KLK6,ARFRP1,ESYT1,VCP,RHEB,OPTN,DPYSL3,HS6ST1,AGPAT2,MAP2,WIPI1,P4HA2,DOLPP1,RAB11FIP1,KPNA2,PIK3C2B,PIEZO1,TTC9,POMT1,RRAGD,BMF,LMTK3,FXYD3,HLA-F,RACGAP1,RAB6A,CNTNAP2,B4GALT4,DHRS3,PGAP1,B4GALNT1,TIMP1,FCHO1,SLC30A6,EXOC8,SELK,MDFIC,FAR2,WNT3A,MPHOSPH9,ALDH3A2,CKAP4,C9orf9,CYP26B1,CHSY3,MGAT4B,KBTBD8,EMC2,ZDHHC3,NMT2,EPN3,MOSPD3,FA2H,H1F0,COL13A1,MFSD2A,P4HA3,ZDHHC7,PLD1,TMEM120A,CDAN1,NIPA1,NF2,P3H2,XYLT1,TP53,P2RX7,ERBB2,FAM198B,LPIN3,EMP2,BCAP31,CYP26A1,SYTL2,SDF4,PDGFA,ATP6V0B,SRPX,WDR44,ZDHHC23,NOTCH3,TMEM64,MINPP1,LMAN1,SULF2,CPD,SIRT1,CLCN3,ERLEC1,EVA1A,ACO1,PTGS2,TAPBP,DNAJC10,ATP1A1,CHMP4B,IRF7,SYT13,AIFM3,ST3GAL1,CNEP1R1,NDST3,POMGNT2,ZC3HC1,COPG1,FAM134B,ARFGEF3,COL9A3,PACSIN2,GOLIM4,CPEB4,TRAPPC10,CD63,TAB3,CTSB,SCD5,NKRF,CRABP2,DSE,LBR,VPS26A,PARM1,DNAJB9,M6PR,ZDHHC21,CDK16,TFAP2A,SLC35B4,UBE2J1,SGK1,CAMK2G,GCNT1,P2RX4,MLEC,RHOA,IFITM3,AMFR,PLAUR,LITAF,PRICKLE1,STMN3,MAML2,CARD19,COL7A1,AKAP3,FNDC3A,TXNDC11,RNPEP,MAPK8IP1,USP6,PRDX4,TMEM50B,SERPINA1,SCG2,PGRMC1,PKD2,SPCS3,NDFIP1,PTGES,GOLGB1,SUN1,LAMP1,SLC35D2,HSPG2,ATP8A1,TAP1,PJA2,PLA2G16,VASH1,RIC1,PICK1,NCS1,SLC9A7,CHST2,CYP1A1,CTGF,STIM1,OSBPL3,STEAP2,KCNS3,SNX16,MARCH2,PACSIN1,TFG,LAMP2,SGCE,SNTB2,BNIP3L,SLC35C1,KIF13A,GALNT7,MCFD2,POR,RAB2B,SGPP1,KDSR,AREG,GNPTAB,BMP1,SARAF,TMEM8B,SPRY4,SLC31A2,F2RL1,RTN3,FGD1,INPPL1,SCOC,TMEM55B,HLA-E,NOTCH2,APBA1,PDXDC1,KIAA1161,MECOM,MESDC2,CALR,DOPEY2,SNX18,ZNRF2,NECAB3,PRKG1,TPST1,SORL1,PIKFYVE,SYTL3,GPR161,EEF1D,TMED2,TRAK2,FAM69A,PIGC,FADS2,B3GNT7,QSOX1,GCC2,KLK5,MMD,LPGAT1,PIP4K2C,VEZT,NPC2,ATP8B3,ANTXR1,GLT8D2,STX3,DGKH,AP1AR,FAAH,ZDHHC20,ARAP1,APPL2,FGD6,KLK7,SAMD8,PLIN3,MAP3K5,NRBP1,EHD1,PLA2G4A,SLC2A4,CEP70,GPR107,TRIP10,CCDC110,NDRG1,CAST,CERCAM,ATP2C2,CD274,BCL2L1,FLT3,CYP39A1,MNS1,EPM2A,ZFYVE9,CD46,CYHR1,CCNA2,ACAP2,TNPO2,CDKN1B,PDE4D,OSBPL7,LGMN,SULT2B1,FLOT2,TMBIM1,GPX4,SEMA3B,MYO5B,DOCK4,SEC23A,TMEM43,COG2,DMTN,PANK1,CLSTN1,KIF1C,SLC11A2,PKMYT1,B3GALNT2,ITPR3,TRIQK,ATP10D,ZMPSTE24,FYN,DDOST,JAK1,STK26,SLC27A1,KLF5,RAB29,HS3ST3B1,B4GALT3,NR3C2,MAMDC2,ANKRD13D,IGFBP6,ATP9A,PLD2,FBXO6,SLC35G2,HLA-A,AKIRIN1,GOLGA2P5,RNF128,MGAT1,FUT8,CD9,SGK3,ATP8B1,MAP3K7,TTPA,CNPY3,MSH6,PDGFC,B3GNT2,VAMP3,FURIN,DIAPH2,C1GALT1C1,UBAC1,YES1,FOS,ARSK,CPTP,NUCB1,CTNS,FGFR2,PRDX3,RIN3,ERAP1,GPER1,FZD5,ARSB,ESYT2,RGMA,EXPH5,FAF2,MPP5,DNER,ERP29,MAP1LC3B,TRIM68,ABCD4,CHPF,ZFYVE16,RAB15,GRHL1,CASC4,METTL7A,IMPAD1,PHTF1,DLG1,SUN3,RAB20,RP2,CTTN,TECR,MYRIP,RASGRP1,LAMP3,CYP1B1,CERS2,ATL1,SOD1,LAP3,SYNE3,ACBD3,PTGFRN,TCN2,MAN2A2,KCNK1,GLA,CHPT1,NRGN,RAP1GAP,PCSK5,STARD3NL,FAM213B,PIFO,SERPINE2,ELOVL7,ATP6V1E2,ADAMTSL4,QSOX2,B3GALNT1,CES2,FAM20C,OCRL,COL6A1,SUCO,PRKCI,HLA-C,NCEH1,CCDC88A,SNX7,KDELR1,PARD3B,GYLTL1B,FBXO8,PRRC1,C3orf58,STEAP1,EGFR,GLCE,GNAS,INSR,PLPP3,TMEM30A,SH3BP4,RAB31,CTSA,JAK3,COL16A1,APOL2,SNX30,DRD1,IL15,PDIA5,COL18A1,MICALL2,EXT2,CYP4F11,ZDHHC12,REEP1,SMO,STEAP3,RPN2,ECE1,PDIA6,LOXL1,F2R,SCYL3,SEPHS1,CHP1,EBAG9,SOAT1,KREMEN2,C3orf52,AP5M1,ERBB2IP,TMTC2,CASP4,SECTM1,CANT1,CYP2U1,REEP4,ABCA1,KDELC2,GLIS3,ANXA3,CDS2,SORT1,JKAMP,SH3D19,TGFBR1,COL4A5,POMGNT1,XPR1,ITGA2B,SNX13,ADORA1,A4GALT,RRBP1,KIAA0319,ZDHHC13,TRIM3,HSPA13,SLC35A1,RPGR,MYO5A,B3GALT6,SUN2,SYPL1,RAB3B,NR4A1,SYBU,LEMD2,CTSL,HLA-B,RND3,DHRS2,CTSV,RAP2C,CSGALNACT1,ARRB1,GLB1,PLOD3,ABCG1 |
| 3.597e-23 | -51.68 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | 487 | 156 | 17758 | 2588 |
FAM171B,ACVR1,EPAS1,AASS,TRIM5,ATP8A1,TSC22D3,EPHA4,MCCC1,LMCD1,ELMOD2,ZYX,SESN3,CYP1A1,CTGF,CDKL5,ALDH1A3,KLF3,DUSP10,CLDN4,TACSTD2,NTN4,SLC39A10,KRT80,CD55,SNTB2,SERTAD4,SLC17A5,LOXL2,LHFPL2,OPTN,TRAM2,MAP2,PLK2,CAB39,PIK3C2B,NFKBIZ,TRAF5,SLC31A2,GAB1,HOXC13,PRSS8,BMF,PARP12,NUAK1,DNAJB2,ABCG2,DOCK11,B4GALT4,CCDC64B,MECOM,ELF3,TNS3,FRAS1,LIMCH1,LRIF1,EPB41L5,PCDH1,HPS3,SALL4,CORO2A,ANO6,FHL2,PDE5A,KIAA1109,NPHP3,KDM3A,PCTP,IL1R1,TMEM30A,MATN2,SH3BP4,APPL2,ZDHHC7,EFNA1,MAP3K5,SERPINB1,LMO7,UGP2,LFNG,CAST,ERBB2,FTH1,IL13RA1,SYTL2,CDS1,CD46,N4BP3,CDH3,IFIT1,RAB27B,EGLN3,LGALS8,COQ10B,PTGER4,ATP1B1,DUSP4,ALCAM,ATP10D,MYL12A,FZD7,WWTR1,ZNF704,MAOA,TLE1,KLF5,ST3GAL1,ABCA1,ANXA3,FBLIM1,PINK1,CPEB4,PARP14,MACC1,FRMD6,ARL4C,OSGIN2,GDF15,CRABP2,DSE,SH2D4A,RND1,SYDE2,DTX3L,ITGB8,MGAT4A,BMP7,CALD1,DRAM1,TFAP2A,UBE2J1,CITED2,SLC35A1,ATP2B1,DUSP1,PARP9,PVRL4,HES1,PHF20L1,ARAP2,TACC1,RAPGEF2,DIAPH2,PRICKLE1,LRRC1,CRISPLD2,FAT4,RND3,PGM2L1,UACA,SH3BGRL2,ITGAV,L1CAM,CPEB2,AHR,ABCG1 |
| 7.552e-23 | -50.94 | JOHNSTONE_PARVB_TARGETS_3_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_UP | 410 | 138 | 17758 | 2588 |
GAA,UNC93B1,AGRN,LGR4,EPAS1,F11R,PLA2G16,LTBP3,EPCAM,P4HB,OSBPL3,CLDN4,TACSTD2,ARNT2,CTTN,PTPRE,KRT80,ATL1,CD55,TRIM8,TNIP1,NFE2L1,LOXL2,SLC17A5,OPTN,RBM47,AREG,CTNND1,CAPN1,GRN,PARP12,HLA-E,HLA-F,ABCG2,ASAH1,NOTCH2,S100A2,DUSP5,GNS,FLII,ITGA3,TIMP1,FRAS1,PAK2,FXYD5,MDFIC,HLA-C,CTSD,ALDH3A2,SPATA20,MFI2,MGAT4B,PYGL,NPC2,RHOB,FNTA,CSF1,NFKBIA,NLRC5,OSMR,CTSA,PLD1,TOB1,EHD1,GPR107,IQGAP1,MORC4,COL18A1,PHLDA1,CCND1,RCN1,APLP2,SCNN1A,SRPX,BRI3,VAT1,STEAP3,ECE1,LGMN,FLOT2,DVL2,CPD,TIMP2,LGALS8,TMEM43,S100A4,LYRM1,HTATIP2,TANC1,C15orf39,KCTD2,DAG1,ALDH3B1,TAPBP,ATP1A1,JAK1,DDOST,ABHD12,STAT6,ST3GAL1,ABCA1,TTC8,ENO2,CTSB,ARL4C,FAM134A,EFHD2,POMGNT1,NTAN1,LGALS3BP,ICAM1,H1FX,ADD3,TMEM87B,CALD1,TOX2,CST3,FUT8,CD9,CITED2,FAM134C,CRTAP,TGIF1,MLEC,IFITM3,LITAF,SNTB1,CRISPLD2,HLA-B,BTG1,SCG2,CCDC69,UACA,ARRB1,CLIP4,GLB1,NDFIP1,L1CAM |
| 1.316e-22 | -50.38 | protein binding | molecular function | GO:0005515 | 10510 | 1773 | 16491 | 2452 |
IBTK,GRIK2,HEXB,RET,TRAPPC8,TGOLN2,ISOC2,BAIAP3,LACTB2,SNX9,FAM46C,SPSB1,CMTM6,CARD10,LTBP3,GRM5,LYPD5,NPM2,CDKN2C,NAPG,MUC4,UBE2T,PAQR5,DNM2,CLDN4,CRY2,PPP1CA,WBP4,TIAM1,IL10RB,CPE,DSTN,UXT,CDA,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,GINS4,LCP1,PIAS3,ENPP1,CARHSP1,PLCG1,MPRIP,MID1IP1,ATP7B,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,HSPB1,STARD13,ANXA11,NXT2,SCN5A,GGA1,SEC61G,ITGA6,RAB23,GPSM2,CCDC64B,FAM21C,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FLII,ZCCHC17,PAIP2B,RIMS3,MEGF8,FLRT3,FBXO7,RANBP1,FBXL14,MAP3K9,SLAIN2,USP1,FAM84B,MYDGF,CNGA1,ZMYM1,MAPK7,MOXD1,ULBP2,MYLIP,NUP85,PHKG2,PPP6R1,MCCC2,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,PCTP,GNA11,PSMA4,PLIN5,IL1R1,FNTA,SLC4A4,ETS2,RAET1L,S100A5,DGAT2,CLMN,STK39,GDF11,TMEM159,CBX5,NUP58,TMEM173,RUSC1,DOCK9,DMPK,TPRN,NQO1,INPP5D,CD82,PTTG1,APOO,C5orf30,MAPK4,GRK6,MVB12B,REPS1,APPBP2,RCN1,RBM23,MUC16,CDH1,SH3BP1,TAX1BP3,LRP11,DLG3,ZNF365,SNX10,ETV4,MX1,TMCC2,SNX8,SEC61B,COL6A2,RIPK2,AGPS,PFKFB2,SEPT6,PTPN9,SAT1,VPS4B,HTATIP2,SYP,GTF2A2,SNX12,TRIM7,EBF2,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CCNB3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,ISOC1,MAPK12,CTHRC1,TCAF1,MZT1,HSP90B1,MPZL1,BACE1,TRAF2,ESRP1,DCAF7,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,CTSZ,ZNF219,HDGFRP2,IFT27,NFAT5,BEX2,SGPL1,CTNNBIP1,DIRAS3,PDCD10,ITGB8,IGSF9,GPC3,CST3,TUBGCP6,KLC3,BAX,FAM102A,IGFBP2,RAG1,MED22,PARP9,PVRL4,PLSCR1,TACC1,PIK3R1,DUSP23,NUB1,UBE2A,CXorf57,PGBD1,RAB3IP,PIM3,CNTNAP1,LDLRAP1,RPL12,PROM1,RAB11FIP2,SYT7,DBI,FAM3C,NR4A3,FBXO44,SSNA1,ITGAV,CD81,SRSF9,ACOT7,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,NDRG2,DNAJB11,F11R,NENF,MGAT5B,SPTB,SLC9A3R2,FANCI,TFAP2E,PLS3,SUSD2,CPNE2,BTG3,RPS6KA2,NUP210,CTNNB1,RABEP2,NPNT,P4HB,IL6ST,ARL1,PSMC2,MITF,PASK,NTN4,SCARA3,SMAGP,PLK1,THRB,KRT80,KCNIP3,PTPN18,STAU2,CBX6,NFE2L1,CR2,CCBL2,ARFRP1,NKAIN1,EAF2,DZIP1L,TNS4,TRIM9,TRAM2,PLEKHG6,KCNMB4,KLF12,HOXA9,KLF11,KPNA2,TC2N,MYL12B,RRAGD,RMND5A,PRSS8,RUNX2,USH1C,HJURP,LGALS3,DNAJB2,FXYD3,PDCL,PSMD7,SORBS3,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,ANO1,MYO5C,TNS3,TIMP1,KIF13B,ICAM5,TBCD,FCHO1,SELK,AHCY,PIM1,NTN1,WNT3A,DPYSL5,RGMB,ZNF320,EMC2,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,PRX,CDK5R1,COL13A1,P4HA3,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,SMCO4,RAD21,HOXB7,TP53,P2RX7,BAHD1,STIL,PCBP1,EMP2,BCAP31,TMSB15B,SYTL2,IER3,PDGFA,KMT5C,TACC2,LMO4,PPME1,BCL6,PLK4,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,PPIF,CLCN3,ERLEC1,AKT1,KIAA0040,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,TAPBP,PTPRJ,IDE,PAFAH1B3,RBL1,STK38,CHMP4B,XRCC3,EFNA5,IRF7,SYT13,ARHGAP4,FAM134B,CTDSP1,BIN1,ZMAT1,PINK1,CPEB4,TAB3,CTSB,GNAL,CDCA8,ERCC6L,GDF15,HMGN3,LBR,AIP,IL22RA1,VPS26A,DNAJB9,FZD6,SH2D4A,NRP2,CD109,FOXP2,CDK16,ALPP,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,IL17RA,TRIM21,ALDH7A1,HMGCL,CPLX1,SYK,FAM134C,ATP2B1,GCNT1,DUSP1,WBP5,NFE2L3,P2RX4,HES1,FBLN5,RHOA,HMGN5,GUSB,PLAUR,PRICKLE1,DPP9,STMN3,COL7A1,BBS2,TXNDC11,USP6,BCL10,DDX23,CNOT2,SCG2,NIPSNAP3A,FGF18,E2F1,SH3BGRL2,ICOSLG,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,TXN,SSH1,LGR4,HSPG2,VANGL1,TMEM86B,TSC22D3,CUL1,CAMK1D,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,PAK6,TYMP,HELZ2,CYP1A1,STIM1,OSBPL3,PALD1,FOSB,POLL,PIK3CA,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,SPATA18,ACVR1C,CDYL,BNIP3L,KIF13A,LDB2,POR,RAB2B,ANKRD10,SH2D3C,PPP2R4,PRDM5,BMP1,MAPK13,NFKBIZ,SPRY4,WBSCR27,F2RL1,FGD1,SEMA6B,RECQL,MRC2,CDKN1C,SCOC,DHPS,TBC1D1,THEMIS2,PRKAA1,AKAP17A,TXNDC9,APBA1,S100A2,PSIP1,SH3RF2,MESDC2,CALR,C9orf69,LYPD3,BHLHE41,VASN,PPP4R1,MSH2,DAPK1,TMEM51,PRKG1,OSTF1,CACNA1D,DLX4,SYTL3,SOCS5,TRAK2,GCC2,KLK5,CEP89,ADCK3,CALM1,WHSC1,PYGL,NPC2,EPHA1,ANTXR1,JADE2,MMP15,NT5C2,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,C1orf21,MATN2,AGBL5,PIAS2,MPP2,FAM83D,ARAP1,APPL2,SFMBT1,CABIN1,CDK18,PLIN3,PER3,HOOK1,IFIH1,EHD1,FOXO6,SPRED1,KIF3C,TCF25,DLGAP5,GPR107,REPS2,THRA,DDIT4L,RALBP1,NDRG1,CCDC110,ATP2C2,BLCAP,FTH1,BCL2L1,TMEM19,FLT3,DDR1,ZFYVE9,EPS8L2,EPM2A,CD46,NOV,CCNA2,ACAP2,RALB,BRI3,PDE4D,EPHB4,OSBPL7,TSPAN1,SULT2B1,FLOT2,NAGA,MED30,SEMA3B,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,UTRN,CLSTN1,KIF1C,ATP1B1,RAD17,PKMYT1,PYGO1,ASB13,CBL,ITPR3,ALCAM,ATP10D,FZD7,CEP162,DDOST,NGFRAP1,TRIOBP,CBX7,COBL,PRKAR1A,PLSCR4,DEPDC1,IGFBP6,CENPI,EPS8,NES,CBLL1,HERC5,PLD2,FBXO6,SPDL1,FGF19,EFNB1,HLA-A,WWP2,CKAP5,E2F7,RNF128,GNB5,FUT8,DRAM1,CD9,ERBB3,CITED2,TTPA,MSH6,FARP2,TGIF1,PDGFC,ZWINT,LONRF3,PAPD7,ZC3H11A,TCFL5,DIAPH2,FBXO9,UBAC1,YES1,AIF1L,FOS,KIF11,CRTC2,DCTN6,CDK5RAP1,TIMP3,SEC14L4,FGFR2,TBX18,RIN3,ABCB1,RYK,ERAP1,RABL6,LRRK1,WDR62,FZD5,ESPL1,DEF6,MELK,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,MPP5,COMMD5,MAP1LC3B,ERP29,SLC8B1,ECI1,TRIM68,EPCAM,ZFYVE16,SIPA1L2,RAB15,HSF2,CDKL5,SIVA1,TRPC1,ASH2L,CTTN,MYRIP,IL1RAP,CERS2,TRAPPC13,CXXC5,CENPA,ASXL1,ITCH,ACBD3,USP18,TYSND1,GPRC5B,HPSE,MADD,TDRD7,SH3GLB2,CAB39,ZNF165,GLA,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,PPP1R12A,PYROXD2,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,DUSP5,SPP1,NOXA1,FAM20C,PFKL,OCRL,COL6A1,PRKCI,BRAT1,LIMCH1,NPTN,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,SNX7,ELK3,PODXL2,SPA17,VWA1,KIAA1109,PRRC1,NUBP1,PDIK1L,RANBP9,RHPN1,SOX13,INSR,UAP1,TMEM30A,SH3BP4,DCUN1D1,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,APOL2,RARG,AFAP1,SNX30,DRD1,CCNE2,LZTFL1,DYNLRB1,SORBS1,PAX6,FAM214B,HDAC11,SOD2,PDIA5,COL18A1,MRAS,OSR2,PHLDA1,EXT2,KCTD9,MXD1,ARTN,KIF14,REEP1,ZBTB49,DIXDC1,ECE1,EPB41L4B,NFKB2,UPF3A,CHP1,SEPHS1,SOAT1,PTPRU,C3orf52,TMTC2,CD40,CDC25C,PDHX,SOCS3,HSF4,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,SHPRH,CIT,SH3D19,ARHGEF7,SERPINB9,TGFBR1,INTS8,TRIB2,RBP7,ITGA2B,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,ACTA2,ARVCF,H2AFY,KANK2,CLIP2,RPGR,MYO5A,PGM1,PHF20L1,WNT10B,SYBU,RGCC,NADK2,RUNX3,TCEAL8,LEPR,ARHGAP24,CTSL,CD8A,CASP7,SWAP70,RND3,TRIM69,CTSV,FIBCD1,UACA,ARRB1,GRAMD1C,MCUR1,CEP41,PLOD3,AHR,RAB3IL1,CD33,ABCG1,DOC2A,ACACB,TRIM24,ADD1,IL15RA,TRIM5,DNAJC3,SMARCAL1,FBXO2,XIAP,DHX8,NRG2,IL18,CNTROB,MORF4L2,SYTL4,CA8,KIF26A,BARD1,PHF1,TP73,CALM2,DAPK2,WEE1,ZYX,TGFBR3,AP1M2,CABP1,CYP2S1,ALDH1A3,PPP1R16A,KLF3,TUBG1,SEMA3G,ACOX2,MANF,TINAGL1,PIK3CD,APOBEC3G,TUBA4A,VPS11,SMARCA2,TNIP1,SH3BGRL,SPRTN,RNF11,LOXL2,F12,ICMT,MYOM1,SLC44A3,PGF,CAMK2N2,WDR11,DNM1L,LIMK1,MYLK,MAP3K11,SERPINB6,ARF6,E2F8,GAB1,HOXC13,NFKBIE,TMTC3,NUAK1,SOX9,STRN4,ZNRF3,MERTK,LMNA,ELF3,GNS,DNPEP,WDFY1,CD22,NEK2,NCAM1,C9orf72,UFD1L,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,ILK,TP53INP2,RHOB,DCP2,CYB5A,DHX32,PTPRF,NCOA3,SCARB2,NAAA,TIMM8A,SEMA4D,HTT,SETD3,ITPR1,OSMR,AURKA,DYSF,MDH1,ALG2,MAL2,NDE1,FBXO27,ARPC2,TRPC3,ZNF502,RPS6KA3,CSRP2,XDH,EGLN1,MTM1,GRHL2,TMSB15A,TUBB4B,FAM131C,ACTR8,ETNK1,RGS20,WDTC1,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CCND1,RNF220,SCNN1A,SP100,DACT1,RAB27B,ARL4D,CDKN2D,RNF169,SSH3,CAMSAP3,PSRC1,LGALS8,NRBF2,FZD4,PLEKHO1,SYNE2,CYS1,NUSAP1,PXYLP1,RAB38,IRS2,PEX5,STX10,TTC12,WWTR1,SIPA1L1,INPP4B,TRABD2A,PDXK,RGS14,ARNT,TTC8,FARP1,TNRC6C,TAOK2,NKX3-1,RASSF7,PDIA3,PKN1,NUCB2,TMA16,ETS1,GSTP1,ARHGEF40,TSPAN17,TIPRL,SRPX2,ICAM1,NEO1,PDIA4,DTX3L,CAPN2,CXCL16,ANK1,ADD3,IRAK1,CTSC,FAM160A2,ANKS1B,ALG13,CALD1,FDXR,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,ZNF230,MAPK11,AK3,ITM2C,TPCN1,S100A6,CRTAP,MOB4,AMOTL2,LCA5,FMN1,CTNNAL1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,PLEKHA7,EMP3,BLVRA,FAM109A,NEURL1B,SNTB1,SKA1,ABLIM2,TXK,GALNT3,PITX2,BTG1,KIAA0141,CCDC6,ACVRL1,NR1D2,ATXN7L3,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,USF2,CYBRD1,FOXA1,MYL9,UNKL,SIGIRR,TRIM2,AGRN,GNPDA1,CUL4B,EPHA4,SUDS3,MCCC1,NDC80,CDIPT,HDAC6,PDGFB,NUP62CL,SDC1,PCNA,SHC3,CNTRL,MKRN3,PXMP4,TLN2,ANO4,TRAM1,S100A13,NEB,PCGF5,CD55,ING1,EZR,TNFAIP8L1,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,PLEKHB1,RHEB,OPTN,DPYSL3,MFAP3L,TBC1D17,CDCA4,WIPI1,MAP2,P4HA2,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,EPB41L4A,PRKAA2,BMF,HLA-F,UBASH3B,RACGAP1,CNTNAP2,DOCK11,IL18R1,SSX2IP,CORO1B,BMP2,RB1,VASP,IGF1R,GATA2,PAK2,EXOC8,MDFIC,TMEM8A,PSMA5,C9orf9,TESK1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,UNC45B,G2E3,SMN1,MAPKAPK2,EPN3,ZC2HC1A,H1F0,PVRL2,ITGA7,CSF1,PRPS2,LTBP2,ATP1B3,CTBP1,IFI6,RNF146,AVPI1,NF2,UGP2,UPF3B,FOXM1,CCDC68,ERBB2,RASGRP3,CCNL1,C1orf116,SDF4,PER2,CDK14,RAD23A,LHX6,PLCG2,SRR,GYS1,EGLN3,DVL2,CTH,SIRT1,TIMP2,MBP,TCEB2,FIGNL1,S100A4,CDC20,MYL12A,MYPOP,DNAJC10,RTN4RL1,ATP1A1,C19orf66,PSMD3,PTK7,ANXA9,ZBTB6,RPL22,LTA4H,CNEP1R1,POMGNT2,CMTM4,COPG1,ZC3HC1,GSDMD,PACSIN2,TRAPPC10,MACC1,CD63,ADGRG1,DAP,RUSC2,GNE,SWI5,GABRG2,PSMD10,SELL,NKRF,JAG2,CRABP2,SIRPA,PPP2R3A,CCDC92,CEP97,MAGEE1,SLC35B4,BUB1,ABCD1,HEXIM2,FAIM,CAMK2G,FAH,HMMR,DLGAP1,MLEC,PSMB4,NR3C1,IFITM3,CRB3,AMFR,LITAF,PPARA,CAPNS1,CARD19,FXR2,PELI3,AKAP3,BCAR1,BORA,NPDC1,MAPK8IP1,SCRN2,PRDX4,SERPINA1,FAT4,TWSG1,ZMYND19,CDCA7L,NMI,CFAP77,NETO2,PGRMC1,TMEM248,CLIP4,PPP2R3C,PKD2,ACADM,GUCD1,NDFIP1,UBE2C,DIS3L,SUN1,ACVR1,PPP4R4,TTC39B,ATP8A1,KLC2,TAP1,GATA3,CCNB1,PLA2G16,FAM101B,RIC1,NCS1,CTGF,ELMO2,PRICKLE3,IQCE,ZFP36,RGS3,IL31RA,RCAN3,TFG,PACSIN1,LAMP2,ORAI2,KIFC2,SNTB2,PBK,CASP9,AGO4,TNS1,AURKB,CCNF,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,AHRR,SLC25A4,AREG,PLK2,GNPTAB,TBX1,NKD1,FAM110C,SARAF,EIF4EBP2,TMEM8B,UNC5B,TRAF5,RTN3,LZTS1,DLAT,DDX58,KLF2,CDK17,MRPL44,INPPL1,FRMD4A,HLA-E,DGKQ,C6orf106,KIF23,NDUFA4,ISYNA1,NOTCH2,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,NECAB3,SORL1,TNFRSF12A,CD70,PIKFYVE,CTSD,TSPAN33,RIMS2,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,MFI2,B9D2,MICB,AMER1,ANO6,PTPRH,PIP4K2C,CFAP206,VEZT,PKM,CYFIP2,KDM3A,FBXO10,RASA1,STX3,FAS,GABRD,PRKAG2,CSNK1G1,DCK,NAB2,TCEAL4,FGD6,NR4A2,EFNA1,MAP3K5,NRBP1,IRF1,ELK4,SLC2A4,CEP70,NLRX1,S100A11,TRIP10,RPS6KA1,IQGAP1,SUZ12,CAST,RNF182,CD274,NUDT12,MNS1,TMPRSS4,GNB2,CYHR1,APLP2,FAM46A,DOK4,TNPO2,CDKN1B,DAB2IP,IFIT1,PHKA2,NR2C1,TMBIM1,TBC1D10B,MYO5B,SEC23A,CDKN2AIP,SLC5A11,TMEM43,CAPN6,DMTN,SLC11A2,PRKCQ,BCL7B,LINC01588,H2AFV,SP4,NIN,CMTM7,EPHA10,OSBPL2,FYN,JAK1,PPP2R5A,STK26,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,MLKL,NR3C2,ATMIN,MRPS9,WASF3,NUDT6,ARHGEF3,PCOLCE,ARL4C,CDCA3,CYB561,APOBEC3H,TEAD3,RND1,SNTA1,AKIRIN1,FAM111A,C16orf59,OXCT1,PHF7,PTEN,CENPJ,PRC1,SGK3,ATP8B1,ERCC2,TAGLN2,CNOT6L,MAP3K7,GFI1,CNPY3,SPRY2,OSGIN1,NCOA2,SMC4,RASGRF1,SHMT1,CASK,MPP1,TEF,PARP4,FURIN,VAMP3,C1GALT1C1,NUCB1,RGS9,RCBTB2,PRDX3,AMMECR1,SERPINB5,CSTF2,GRIN2D,GPER1,NCAPG2,OCLN,ESYT2,USP16,EXPH5,EMX1,LTBP1,CASP3,NMRK1,ST13,CAMKK1,UBE2Z,KIF2C,TAF6L,CACNB4,DNER,DENND2D,KREMEN1,SH3KBP1,CHPF,MAGOHB,C7orf49,LRRC6,ZCCHC12,TSPAN6,DPYSL2,DLG1,CAPG,POF1B,KIF22,SUN3,RP2,NFU1,MYH14,ARNT2,TECR,PTPRE,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,TRIM8,SYNE3,ASCL5,ROR1,PTGFRN,EDNRA,MDK,CXXC4,NEIL1,ZNF114,ARHGEF19,ADIPOR1,APBA2,RAP1GAP,PSMC1,MIIP,PPP2R5D,GRN,PIFO,LRRFIP2,PEX6,ELOVL7,ASL,ATP6V1E2,SAMD9,PHLPP1,CA2,KCNN4,EBF4,FNIP1,FXYD5,KNTC1,RFX5,SIMC1,LRIF1,ALS2CL,HP1BP3,OXR1,GYLTL1B,HMG20B,RNF113A,EGFR,GNAS,FECH,BCAR3,NUDT16,TSC1,PLPP3,NFKBIA,CDCA5,EGFL7,YOD1,KIF12,FBXW5,GAS2L1,SPC25,FAM92A1,IL15,ABCG4,MORC4,ZMYND10,PATL2,MICALL2,ARHGEF16,LRRC45,SLC25A48,SS18,KCTD15,SETDB2,SMO,GOT1,TWIST1,STEAP3,APIP,F2R,PDIA6,SCYL3,HSPA2,FRS3,MAP3K3,GCA,TAF5,BAG4,IGSF8,ERBB2IP,KCTD2,BFSP1,BHLHB9,PEX2,PLXND1,SGOL1,REEP4,LIFR,CBX4,CCDC24,ANXA3,SORT1,JKAMP,FRMD6,POC1B,LRP4,ARMC7,AES,TRMT2B,POMGNT1,FAM167A,ZNF212,SAC3D1,ADORA1,MLPH,KIAA0319,CKS1B,TRIM3,BRD7,HSPA13,MXD3,IQGAP3,SUN2,ADAM17,RAB3B,ASPM,PHLDB3,NR4A1,GCLC,MBNL3,OGDHL,POLD3,MAP1B,KLHL2,HLA-B,DHRS2,PRCP,HNRNPH2,UBE2D2,OTUB2,GLB1,GEM,ATP6V1C1,SOX8,L1CAM,SNPH |
| 7.118e-22 | -48.69 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | 1094 | 276 | 17758 | 2588 |
TTC39B,PNPLA2,KLC2,HEXB,TAP1,FBXO2,GATA3,IL18,LYNX1,PLA2G16,FAM101B,SLC20A1,SPSB1,SLC35E4,UBE2T,STIM1,ZFP36,FOSB,AOX1,DNM2,SNX16,ACOX2,TINAGL1,TIPARP,TUBA4A,DSTN,MCFD2,ICMT,RNF19B,SGPP1,PGF,ANKRD10,PIAS3,CARHSP1,AREG,GDE1,PLK2,SH2D3C,BMP1,ITPKA,NFKBIE,TBC1D1,ITGA6,DGKQ,ISYNA1,TSPAN7,ELF3,GNS,DOPEY2,ZNRF2,VASN,TMEM51,DAPK1,PCYOX1,USP38,TTLL1,TSPAN33,EPHX1,QSOX1,UFD1L,MMD,PQLC3,LPGAT1,FHL2,NPC2,TP53INP2,PCTP,STX3,FAS,MMP15,ARAP1,DGAT2,MDH1,CDK18,EFNA1,MAL2,IFIH1,RUSC1,EHD1,DMPK,NLRX1,TUBB4B,ST14,INPP5D,DDIT4L,KCTD12,BLCAP,CD274,TMEM19,DDR1,CYHR1,SCNN1A,SP100,DOK4,FICD,TNPO2,IFIT1,TMBIM1,MX1,TMCC2,PSRC1,PFKFB2,DRAP1,UTRN,TRIM7,FZD7,WFS1,STAT1,KLF5,SLC27A1,OTUD5,CKAP2,ZNF219,SPR,IFT27,EFNB1,TEAD3,LGALS3BP,SGPL1,PDCD10,RNF128,FDXR,DRAM1,ADAM15,FAM102A,ERBB3,CITED2,ITM2C,TPCN1,OSGIN1,MSH6,OPLAH,ARAP2,ALDH2,NUB1,DBR1,EMP3,AK4,FOS,GPLD1,GALNT3,BTG1,LDLRAP1,ACADSB,SERPINB5,HMGA1,CENPE,CMPK2,FZD5,DCBLD1,TMEM184B,CPT2,F11R,GALM,CDIPT,PDGFB,SDC1,SLC9A3R2,PLS3,BTG3,CNTRL,SIVA1,MITF,CAPG,AKR1B1,TNFRSF18,KIF22,S100A13,CXXC5,CD55,CELSR2,CITED4,USP18,EAF2,ESYT1,PRKRA,IDH1,STK17B,PLEKHG6,HS6ST1,WIPI1,SH3GLB2,ARRDC1,SP6,RBM43,RAP1GAP,GLCCI1,PPP2R5D,CAPN1,PRSS8,LASP1,PARP12,SERPINE2,PEX6,DNAJB2,ELOVL7,SSX2IP,RB1,ICAM5,EXOC8,ACAD8,ZRANB1,SLC12A2,TESK1,CORO2A,SPA17,HMG20B,TCF7,IFIT3,CDK5R1,MAPKAPK2,FA2H,CSF1,LTBP2,JAK3,SPC25,UPF3B,IL15,DGKA,MORC4,RHPN2,COL18A1,BCAP31,PDGFA,ATP6V0B,LMO4,SRR,OAS3,ECE1,PPIF,SIRT1,PTGER4,IGSF8,ATP13A2,TAPBP,OVOL1,IRF7,TM2D2,CPEB4,ENO2,CTSB,ARMC7,GDF15,CRABP2,DNAJB9,ITGA2B,SAC3D1,LLGL2,GTF2F2,TRIM21,ARVCF,TSPAN13,MXD3,SLC45A3,MYO5A,FAH,PSMB4,GUSB,CRB3,NR4A1,CRIP2,LITAF,RNPEP,BCAR1,ENDOD1,FUCA1,PRCP,FGF18,NMI,E2F1,PGRMC1,OTUB2,SH3BGRL2,ATP6V1C1,AHR,LRRC57 |
| 1.607e-21 | -47.88 | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | MSigDB lists | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | 400 | 133 | 17758 | 2588 |
LAMP1,TMEM184B,SSH1,EPAS1,CUL4B,HEXB,NANS,ERP29,CMTM6,PLS3,ZYX,CTGF,P4HB,OSBPL3,PAPSS1,CAPG,CTTN,SCARA3,IL10RB,S100A13,LAMP2,KDELR3,LOXL2,MCFD2,IDH1,ARF4,DPYSL3,TRAM2,WIPI1,MYLK,BMP1,GRN,KLF2,MRC2,SERPINE2,RAB23,CORO1B,GNS,TIMP1,CYR61,COL6A1,TPST1,FXYD5,TNFRSF12A,NPTN,EPHX1,SNX7,GFPT1,QSOX1,ELK3,FHL2,STEAP1,EGFR,UAP1,PRPS2,RAB31,OSMR,PITPNA,STK39,EHD1,CCDC109B,AVPI1,NQO1,PAPSS2,IQGAP1,CAST,XYLT1,IL13RA1,BCAP31,CCND1,APLP2,DOK4,VAT1,TWIST1,ACSL4,LMAN1,LOXL1,TIMP2,SEC61B,COL6A2,LGALS8,TMEM43,OSTM1,COQ10B,CASP4,ATP10D,GABARAPL1,TAPBP,JAK1,AXL,STAT6,NRG1,PDXK,MAN2B2,PCOLCE,IGFBP6,BACE1,CTSB,ARL4C,NTAN1,NUCB2,SRPX2,LGALS3BP,IRAK1,PTEN,CALD1,RRBP1,CST3,DRAM1,HSPA13,TAGLN2,S100A6,DUSP1,PDGFC,ADAMTS2,RHOA,FBLN5,PLAUR,VAMP3,UBE2A,C1GALT1C1,RNPEP,NPDC1,PRDX4,ENDOD1,NUCB1,SWAP70,AMMECR1,PGRMC1,PKD2,ITGAV,CD81,PTGES |
| 2.324e-21 | -47.51 | large_cell | COSMIC cancer mutations | large_cell | 15622 | 2408 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,RABEP2,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,TYMP,ANKS6,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TNRC6C,NKX3-1,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,RAD21,CTDSPL,TP53,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,C17orf75,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 3.197e-21 | -47.19 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | 15548 | 2399 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,RABEP2,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,TYMP,ANKS6,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,SUZ12,CAST,IQGAP1,RNF182,EGR3,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,FLRT3,MEGF8,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,RAD21,CTDSPL,TP53,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,CAPN12,GPR107,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,C17orf75,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 3.197e-21 | -47.19 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 15548 | 2399 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,RABEP2,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,TYMP,ANKS6,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TNRC6C,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,SUZ12,CAST,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,RAD21,CTDSPL,TP53,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,IL22RA1,VPS26A,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,GPR107,CAPN12,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,C17orf75,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 3.197e-21 | -47.19 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 15548 | 2399 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,RABEP2,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,TYMP,ANKS6,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TNRC6C,NKX3-1,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,ADO,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,FLRT3,MEGF8,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,RAD21,CTDSPL,TP53,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,C17orf75,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 3.197e-21 | -47.19 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | 15548 | 2399 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,RABEP2,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,TYMP,ANKS6,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TNRC6C,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,SUZ12,CAST,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,FLRT3,RIMS3,ATP5H,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,RAD21,CTDSPL,TP53,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,IL22RA1,VPS26A,SH2D4A,FZD6,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,CAPN12,REPS2,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,C17orf75,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 3.467e-21 | -47.11 | classic | COSMIC cancer mutations | classic | 15549 | 2399 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,RABEP2,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,TYMP,ANKS6,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,SUZ12,CAST,IQGAP1,RNF182,EGR3,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,FLRT3,MEGF8,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,RAD21,CTDSPL,TP53,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,CAPN12,GPR107,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,C17orf75,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 4.789e-21 | -46.79 | medulla | COSMIC cancer mutations | medulla | 15553 | 2399 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,RABEP2,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,TYMP,ANKS6,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,RAD21,CTDSPL,TP53,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,CAPN12,GPR107,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,C17orf75,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 5.191e-21 | -46.71 | desmoplastic | COSMIC cancer mutations | desmoplastic | 15554 | 2399 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,RABEP2,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,TYMP,ANKS6,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TNRC6C,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,SUZ12,CAST,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,RAD21,CTDSPL,TP53,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,IL22RA1,VPS26A,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,GPR107,CAPN12,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,C17orf75,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,KIFC2,NBPF3,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 7.013e-21 | -46.41 | regulation of signal transduction | biological process | GO:0009966 | 2548 | 541 | 16441 | 2455 |
TRIM24,GRIK2,TRIM5,RET,XIAP,NRG2,IL18,KIF26A,CARD10,GRM5,TP73,CALM2,DAPK2,PSMD1,RGS12,TGFBR3,DNM2,CRY2,PPP1CA,TIAM1,TNIP1,SH3BGRL,ICMT,ABR,ENPP1,PLCG1,DNM1L,ANKRD6,TRAF3IP1,NOD2,MAP3K11,HDAC1,TMOD2,ARF6,HSPB1,STARD13,GAB1,NUAK1,ITGA6,SOX9,RAB23,ZNRF3,LMNA,TFAP4,RAC2,WDFY1,FAM13B,MAP3K9,MYDGF,CNGA1,NCAM1,MAPK7,MAPKAPK3,SHARPIN,NPHP3,ILK,PSMA4,RHOB,PLIN5,NCOA3,FNTA,HTT,SEMA4D,ITPR1,GDF11,RUSC1,XDH,ARHGAP11A,LFNG,INPP5D,RGS20,GRK6,MVB12B,PRKACA,APC2,CCND1,ST5,RNF220,SP100,DACT1,TAX1BP3,RASGEF1A,CDKN2D,RIPK2,FZD4,SYP,IRS2,WFS1,SLC9A6,AXL,WWTR1,SIPA1L1,INPP4B,PLEKHG1,TRABD2A,RGS14,ARNT,CTHRC1,FARP1,TAOK2,NKX3-1,TRAF2,BIK,FLOT1,PDIA3,PKN1,GSTP1,ARHGEF40,TSPAN17,NFAT5,ICAM1,NEO1,CTNNBIP1,PDCD10,IRAK1,CTSC,GPC3,MCF2L,BAX,PLEKHF1,TMBIM6,IGFBP2,MAPK11,ITM2C,PLSCR1,BCL9,RAPGEF2,PIK3R1,GRIN1,TXK,CNTNAP1,LDLRAP1,ACVRL1,ITGAV,CD81,SHOX2,FOXA1,SIGIRR,TNK1,AGRN,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,HDAC6,PDGFB,SPTB,CTNNB1,NPNT,SHC3,P4HB,IL6ST,PSMC2,DUSP10,TNFRSF18,RGS5,S100A13,CD55,EZR,TNFAIP8L1,KLK6,PRKRA,SESN1,CDK1,RHEB,OPTN,PLEKHG6,AGPAT2,PRKCDBP,CTNND1,POMT1,RRAGD,PRKAA2,RUNX2,BMF,LGALS3,RASA2,UBASH3B,PDCL,PSMD7,SORBS3,RACGAP1,DHRS3,FBLN1,IL18R1,SSX2IP,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,MDFIC,WNT3A,PSMA5,CYP26B1,SPATA13,STRADB,G2E3,NMT2,CDK5R1,MAPKAPK2,CSF1,NLRC5,IFI6,RNF146,AVPI1,NF2,FOXM1,TP53,ERBB2,P2RX7,RASGRP3,EMP2,BCAP31,CYP26A1,CDK14,IER3,TTC21B,PDGFA,SRPX,BCL6,CDH3,DVL2,CTH,SULF2,SIRT1,PPIF,TIMP2,AKT1,FIGNL1,S100A4,C3orf33,DAG1,PTGS2,PTPRJ,PSMD3,STK38,IRF7,ARHGAP4,ZC3HC1,ARFGEF3,PINK1,ADGRG1,CD63,TAB3,PSMD10,GDF15,JAG2,CRABP2,AIP,PPP2R3A,FZD6,CD109,BUB1,FAIM,SYK,CAMK2G,DUSP1,P2RX4,HES1,RHOA,PSMB4,PLAUR,LITAF,PRICKLE1,STMN3,CARD19,PELI3,AKAP3,MAPK8IP1,BCL10,CNOT2,BANK1,TWSG1,SCG2,FGF18,NETO2,E2F1,PKD2,NDFIP1,HIPK3,ARHGEF9,ARHGEF4,ACVR1,TXN,LGR4,GATA3,PSME1,PJA2,SEPT4,SLC20A1,PAK6,SESN3,CTGF,RGS3,IL31RA,TFG,RCAN3,METAP2,PBK,SLC35C1,SLC25A5,POR,ARHGEF26,ANKRD10,TBX1,SH2D3C,PLK2,NKD1,FAM110C,SPRY4,UNC5B,F2RL1,TRAF5,FGD1,CDKN1C,PRKAA1,NOTCH2,TNFRSF19,KIAA1161,MECOM,CALR,ITGA3,RALGPS2,CYR61,PIK3AP1,VASN,DAPK1,SORL1,TNFRSF12A,EEF1D,GPR161,TSPAN33,SOCS5,KLK5,AMER1,CALM1,RASA1,FAS,PELI2,ARAP1,FAM83D,PIAS2,FGD6,NR4A2,EFNA1,MAP3K5,IRF1,PLEKHG3,SPRED1,TRIP10,NLRX1,RALBP1,DDIT4L,THRA,BCL2L1,FLT3,EPM2A,EPS8L2,ZFYVE9,CD46,APLP2,NOV,DAB2IP,PDE4D,LGMN,FLOT2,NR2C1,TMBIM1,CDKN2AIP,DMTN,PRKCQ,CBL,FZD7,FYN,JAK1,STAT1,KIAA1804,PPP1CB,NRG1,ARHGEF3,IGFBP6,EPS8,PLD2,FGF19,GNB5,PTEN,SLC44A2,ERBB3,MAP3K7,CITED2,GFI1,SPRY2,TRIM62,NCOA2,FARP2,TGIF1,RASGRF1,ARHGEF28,ARAP2,FURIN,FBXO9,RGS9,FGFR2,TBX18,RYK,GRIN2D,LRRK1,GPER1,FZD5,LTBP1,ERP29,TRIM68,KREMEN1,SH3KBP1,ARHGEF10L,SIPA1L2,ARHGEF37,TSPAN6,SIVA1,DLG1,AKR1B1,CTTN,SLC39A10,PTPRE,RASGRP1,CYP1B1,SOD1,TRIM8,CXXC5,ASXL1,USP18,ITCH,RNF165,ARHGDIB,CXXC4,ARHGEF19,HPSE,GPRC5B,MADD,ADIPOR1,RAP1GAP,PSMC1,LASP1,ARAP3,SERPINE2,PPP1R2,CALM3,PHLPP1,DUSP5,FAM20C,KCNN4,OCRL,FNIP1,C10orf54,NPTN,ZRANB1,ALS2CL,MDFI,FBXO8,PDE5A,RANBP9,C3orf58,EGFR,GNAS,ONECUT1,TSC1,INSR,PLPP3,NFKBIA,SH3BP4,RHOBTB2,EGFL7,JAK3,AFAP1,TOB1,SORBS1,IL15,PSME2,SOD2,ARHGEF16,KIF14,SMO,TWIST1,DIXDC1,APIP,F2R,CHP1,FRS3,MAP3K3,BAG4,KREMEN2,ERBB2IP,CD40,DUSP4,MAP3K6,SOCS3,ARHGAP35,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,ABCA1,GCLM,ARHGEF11,TSPAN15,ARHGEF7,LRP4,AES,TGFBR1,NOTUM,TRIB2,HMGXB4,SYDE2,SNX13,CARD8,ADRBK1,ADORA1,LLGL2,BMP7,ZDHHC13,KANK2,IQGAP3,MYO5A,ADAM17,WNT10B,GCLC,ASPM,RC3H2,FOXL1,ARHGAP24,LEMD2,CD8A,PRCP,UACA,ARRB1,L1CAM,NGEF |
| 7.630e-21 | -46.32 | large_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-carcinoma-adenocarcinoma | 17034 | 2554 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ABRACL,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,IL22RA1,VPS26A,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,CEP41,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 7.847e-21 | -46.29 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | 1022 | 259 | 17758 | 2588 |
PNISR,ATP8A1,SEPT4,SPSB1,ELMOD2,CMTM6,ARHGAP42,SESN3,TGFBR3,RGS3,IQCE,SMARCA2,KIFC2,BNIP3L,TMEM151A,TNS1,KIF13A,SLC17A5,ICMT,CCNF,ZFAND5,ULK2,RAB2B,HLF,GNPTAB,NKD1,MYLK,LRIG1,BMP1,SERPINI1,RNASEL,TMEM8B,UNC5B,SLC31A2,GAB1,E2F8,INPPL1,CYP2J2,ADO,SLC1A3,APBA1,ATG4A,WDFY1,RALGPS2,TMEM51,SORL1,FAM69A,ADCK3,LPGAT1,PIP4K2C,WHSC1,PLS1,NPC2,CYFIP2,SPTLC2,TP53INP2,FBXO10,CYB5A,FRMD4B,SCARB2,ETS2,SEMA4D,HTT,SETD3,MATN2,MPP2,DGAT2,APPL2,CLMN,PCDH19,CABIN1,GDF11,MAP3K5,PER3,RUSC1,DOCK9,EHD1,KIF3C,REPS2,TCTN2,CERCAM,NDRG1,CD82,TMEM19,DDR1,TNFSF9,CYP39A1,FAM46A,ENPP5,PDE4D,ZNF365,NAGA,TMBIM1,MYO5B,TMCC2,DOCK4,COL6A2,ERMP1,CAPN6,SAT1,CDCA2,PRKCQ,DNAJB14,ALCAM,H2AFV,ALDH3B1,FYN,PEX5,CDK19,AXL,CORO1C,STAT1,PLEKHG1,GEN1,CBX7,ATMIN,TNRC6C,PCOLCE,FAM189A2,MPZL1,BACE1,EPS8,GPR180,FBXO6,NEO1,SGPL1,WWP2,TMCC3,PDCD10,ADD3,ITGB8,RNF128,CD9,FAM102A,SGCB,AMOTL2,ACBD5,PDGFC,EMP3,C1GALT1C1,FOS,BTG1,TIMP3,FGFR2,RAB11FIP2,NR1D2,FBXO44,ARSB,CD81,CPEB2,LTBP1,KIAA1462,TRIM2,UGT8,TEX2,ITPR2,MAP1LC3B,SDC1,DNER,SLC9A3R2,ABCD4,INPP5E,CPNE2,SLC44A1,CEP78,ABCA2,DUSP10,ANKRD12,PXMP4,PTPRE,ATL1,MARK1,KCNIP3,EZR,NKAIN1,LHFPL2,DPYSL3,LRRC42,MFAP3L,WIPI1,TTC39C,CHPT1,APBA2,BMF,UBASH3B,ELOVL7,SORBS3,CORO1B,SPIN4,COL6A1,EBF4,MTMR10,RFX5,NCEH1,SNED1,CCDC88A,C3orf58,SOX13,SLC6A6,FA2H,COQ10A,CSF1,TMEM30A,ITGA7,SH3BP4,TMEM14A,SHROOM2,AFAP1,COL16A1,SNX30,LZTFL1,SORBS1,SLC25A24,DGKA,MXD1,SDF4,PDGFA,ZDHHC12,REEP1,VAT1,DIXDC1,EPB41L4B,NFKB2,LMAN1,SOAT1,CLCN3,TIMP2,MBP,OSTM1,ERBB2IP,SOCS3,ATP13A2,ABHD12,FAM134B,ZMAT1,GLIS3,PINK1,POC1B,SH3D19,LRP4,COL4A5,PARM1,TMEM63A,HDAC9,FOXP2,LYPD6,FAM63A,FAM134C,MOSPD2,PPARA,PRICKLE1,FAM73B,BCAR1,MAP1B,DDX23,SMTNL2,SOX8,AHR,SAT2 |
| 1.530e-20 | -45.63 | NUYTTEN_EZH2_TARGETS_UP | MSigDB lists | NUYTTEN_EZH2_TARGETS_UP | 985 | 251 | 17758 | 2588 |
KLK10,AGRN,IL15RA,FAM160B1,TRIM5,FAM129B,TMEM41B,TAP1,ARFGEF1,MPP5,PLXNA1,DNER,SPSB1,SNX9,NCS1,TYMP,CTGF,SHC3,CDKL5,CASC4,IL6ST,PAQR5,PHTF1,KLF3,PIK3CA,IRF2,NTN4,RP2,CTTN,TFG,ERAP2,XKR8,LAMP3,LAMP2,SPEF2,CITED4,LAP3,SERTAD4,USP18,NFE2L1,ROR1,ICMT,SGPP1,OPTN,AHRR,ANKRD10,TRIM47,GPRC5B,MAP2,PLK2,P4HA2,LIMK1,TDRD7,CAB39,EIF4EBP2,SERPINI1,SLC31A2,NXT2,DDX58,BMF,RUNX2,PARP12,NFKBIE,ZNF395,SERPINE2,LGALS3,NUAK1,HLA-E,HLA-F,SAMD9,SLC1A3,HERC6,WDFY1,SPIN4,FLRT3,VASN,COL6A1,STT3B,HLA-C,MOXD1,NDUFA12,CCDC88A,CKAP4,FAM69A,PAQR7,SOCS5,QSOX1,RGMB,KBTBD8,VEZT,TCF7,MEST,KDM3A,ZDHHC3,STEAP1,STX3,CYB5A,FAS,PTPRF,NCOA3,SCARB2,NT5C2,AP1AR,UAP1,SLC4A4,ETS2,CSF1,NFKBIA,CGREF1,MATN2,FGD6,YOD1,STK39,ZBTB34,TMEM159,IFIH1,SEMA3A,COL16A1,APOL2,RPS6KA3,IRF1,EGLN1,EHD1,PLA2G4A,SPRED1,LZTFL1,CCDC109B,ARMCX3,PSME2,CAST,NDRG1,RGS20,SOD2,GMPR,RASGRP3,BLCAP,MRAS,APC2,C1orf116,MXD1,APLP2,NOV,FAM46A,SP100,TRANK1,EFR3A,BRI3,RPN2,OAS3,TMEM64,LGMN,RAB27B,LOXL1,CTH,MX1,PPIF,SOAT1,BAG4,RIPK2,LGALS8,PFKFB2,KIAA0040,OSTM1,S100A4,SAT1,C3orf52,ATP1B1,C15orf39,TMTC2,NIN,TAPBP,PTGS2,C19orf66,CORO1C,SECTM1,STAT1,ZNF704,OVOL1,PPP1CB,ADAMTS14,EFNA5,MLKL,NR3C2,DYRK3,HSP90B1,PARP14,FRMD6,POC1B,CTSB,BACE1,ARL4C,PBX3,EFHD2,HERC5,CYB561,GPR180,GDF15,DSE,SRPX2,NFAT5,ICAM1,DNAJB9,ZDHHC21,SLC25A36,DTX3L,ANK1,OXCT1,CTSC,FUT8,RRBP1,DRAM1,SLC44A2,SGK1,TRIM21,FAM102A,ITM2C,TPCN1,PARP9,ACBD5,PHF20L1,ADAM17,PLSCR1,DENND1B,EIF5A2,MYEOV,PLEKHA7,C1GALT1C1,PELI3,MAP1B,CD83,BCL10,USP6,GALNT3,ENDOD1,HLA-B,BANK1,CASP7,PLOD2,RND3,NIPSNAP3A,NMI,FAM3C,NETO2,ERAP1,GLB1,GEM,FZD5,CPEB2,PKIA,JARID2,TMEM131 |
| 1.899e-20 | -45.41 | regulation of signaling | biological process | GO:0023051 | 2886 | 597 | 16441 | 2455 |
TRIM24,GRIK2,TRIM5,RET,CACNA2D2,XIAP,NRG2,IL18,SYTL4,KIF26A,CARD10,GRM5,TP73,CALM2,DAPK2,PSMD1,RGS12,TGFBR3,DNM2,CRY2,PPP1CA,TIAM1,TNIP1,SH3BGRL,PRKAR2B,ICMT,PNKD,ABR,ENPP1,PLCG1,GRID2IP,DNM1L,ANKRD6,TRAF3IP1,NOD2,MAP3K11,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,STARD13,GAB1,NUAK1,ITGA6,SOX9,RAB23,ZNRF3,LMNA,TFAP4,RAC2,WDFY1,RIMS3,FAM13B,MAP3K9,MYDGF,CNGA1,NCAM1,MAPK7,MAPKAPK3,SHARPIN,NPHP3,ILK,PSMA4,RHOB,PLIN5,NCOA3,FNTA,HTT,SEMA4D,ITPR1,GDF11,RUSC1,XDH,DMPK,ARHGAP11A,LFNG,INPP5D,RGS20,GRK6,MVB12B,PRKACA,APC2,CCND1,ST5,RNF220,SP100,DACT1,TAX1BP3,RASGEF1A,CDKN2D,MYT1,RIPK2,FZD4,PFKFB2,SYP,IRS2,WFS1,SLC9A6,AXL,WWTR1,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,RGS14,ARNT,CTHRC1,FARP1,TAOK2,NKX3-1,TRAF2,BIK,FLOT1,PDIA3,PKN1,KCNC4,GSTP1,ARHGEF40,TSPAN17,NFAT5,ICAM1,NEO1,CTNNBIP1,PDCD10,IRAK1,CTSC,GPC3,MCF2L,BAX,PLEKHF1,TMBIM6,IGFBP2,MAPK11,ITM2C,PLSCR1,BCL9,RAPGEF2,PIK3R1,GRIN1,PIM3,FAM109A,TXK,CNTNAP1,LDLRAP1,ACVRL1,SYT7,DBI,ITGAV,CD81,SHOX2,FOXA1,SIGIRR,ILDR1,TNK1,AGRN,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,ITPR2,HDAC6,PDGFB,SPTB,CTNNB1,NPNT,SHC3,P4HB,IL6ST,PSMC2,PASK,DUSP10,TNFRSF18,RGS5,S100A13,CD55,EZR,TNFAIP8L1,KLK6,PRKRA,SESN1,CDK1,RHEB,OPTN,PLEKHG6,KCNMB4,AGPAT2,RAB11FIP1,PRKCDBP,CTNND1,POMT1,RRAGD,PRKAA2,RUNX2,BMF,LGALS3,RASA2,UBASH3B,PDCL,PSMD7,SORBS3,RACGAP1,DHRS3,FBLN1,IL18R1,ANO1,SSX2IP,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,MDFIC,WNT3A,PSMA5,CYP26B1,SPATA13,STRADB,SCRIB,G2E3,NMT2,CDK5R1,MAPKAPK2,CSF1,NLRC5,IFI6,RNF146,AVPI1,NF2,FOXM1,TP53,ERBB2,P2RX7,RASGRP3,EMP2,BCAP31,CYP26A1,PER2,CDK14,IER3,TTC21B,PDGFA,SRPX,BCL6,CDH3,DVL2,SULF2,CTH,SIRT1,PPIF,TIMP2,AKT1,FIGNL1,S100A4,CDC20,C3orf33,DAG1,PTGS2,PTPRJ,PSMD3,STK38,EFNA5,IRF7,ARHGAP4,ZC3HC1,ARFGEF3,PINK1,CD63,ADGRG1,TAB3,PSMD10,GDF15,HMGN3,JAG2,CRABP2,AIP,PPP2R3A,FZD6,CD109,CDK16,BUB1,FAIM,SYK,CAMK2G,DUSP1,P2RX4,HES1,RHOA,PSMB4,PLAUR,LITAF,PRICKLE1,STMN3,CARD19,PELI3,AKAP3,MAPK8IP1,BCL10,CNOT2,BANK1,TWSG1,SCG2,FGF18,NETO2,E2F1,PKD2,SPCS3,NDFIP1,HIPK3,ARHGEF9,ARHGEF4,ACVR1,TXN,LGR4,GATA3,PSME1,PJA2,SEPT4,SLC20A1,PICK1,PAK6,SESN3,CTGF,RGS3,IL31RA,KCNS3,TFG,RCAN3,METAP2,ACVR1C,PBK,SLC35C1,SLC25A5,POR,ARHGEF26,ANKRD10,SLC25A4,TBX1,SH2D3C,PLK2,NKD1,FAM110C,EIF4EBP2,SPRY4,UNC5B,F2RL1,TRAF5,FGD1,CDKN1C,PRKAA1,SLC1A3,NOTCH2,TNFRSF19,KIAA1161,MECOM,CALR,ITGA3,RALGPS2,CYR61,PIK3AP1,VASN,DAPK1,SORL1,TNFRSF12A,CACNA1D,GPR161,EEF1D,RIMS2,TSPAN33,SOCS5,KLK5,CALM1,AMER1,RASA1,STX3,FAS,AP1AR,PELI2,ARAP1,FAM83D,PIAS2,FGD6,NR4A2,EFNA1,MAP3K5,IRF1,PLEKHG3,SPRED1,TRIP10,NLRX1,THRA,IQGAP1,RALBP1,DDIT4L,BCL2L1,FLT3,EPM2A,EPS8L2,ZFYVE9,CD46,APLP2,NOV,DAB2IP,PDE4D,LGMN,FLOT2,NR2C1,TMBIM1,CDKN2AIP,DMTN,CLSTN1,PRKCQ,ITPR3,CBL,FZD7,FYN,JAK1,KIAA1804,STAT1,PPP1CB,NRG1,PRKAR1A,ARHGEF3,IGFBP6,EPS8,PLD2,FGF19,OXCT1,GNB5,PTEN,SLC44A2,ERBB3,MAP3K7,CITED2,GFI1,SPRY2,TRIM62,NCOA2,FARP2,TGIF1,RASGRF1,ARHGEF28,ARAP2,FURIN,VAMP3,FBXO9,GPLD1,RGS9,FGFR2,TBX18,RYK,GRIN2D,LRRK1,GPER1,FZD5,LTBP1,ERP29,SLC8B1,KREMEN1,TRIM68,SH3KBP1,ARHGEF10L,SIPA1L2,ARHGEF37,TSPAN6,SIVA1,DLG1,AKR1B1,CTTN,SLC39A10,PTPRE,MYRIP,RASGRP1,CYP1B1,SOD1,TRIM8,CXXC5,ASXL1,USP18,ITCH,RNF165,ARHGDIB,CXXC4,ARHGEF19,GPRC5B,HPSE,MADD,ADIPOR1,RAP1GAP,PSMC1,LASP1,ARAP3,SERPINE2,PPP1R2,BVES,CALM3,PHLPP1,DUSP5,CA2,FAM20C,PFKL,KCNN4,OCRL,FNIP1,NPTN,C10orf54,ZRANB1,ALS2CL,MDFI,FBXO8,PDE5A,RANBP9,C3orf58,EGFR,GNAS,ONECUT1,TSC1,INSR,PLPP3,NFKBIA,SH3BP4,RHOBTB2,EGFL7,JAK3,AFAP1,TOB1,DRD1,LMO7,SORBS1,IL15,PSME2,SOD2,ARHGEF16,KIF14,SMO,TWIST1,DIXDC1,ECE1,APIP,F2R,FRS3,CHP1,MAP3K3,BAG4,KREMEN2,ERBB2IP,DUSP4,CD40,MAP3K6,SOCS3,ARHGAP35,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,ABCA1,GCLM,ARHGEF11,TSPAN15,ARHGEF7,LRP4,AES,TGFBR1,NOTUM,TRIB2,HMGXB4,SYDE2,KIF5B,SNX13,CARD8,ADRBK1,ADORA1,LLGL2,BMP7,ZDHHC13,KANK2,IQGAP3,MYO5A,RAB3B,ADAM17,WNT10B,GCLC,ASPM,RC3H2,SYBU,FOXL1,ARHGAP24,LEMD2,CD8A,PRCP,UACA,ARRB1,L1CAM,NGEF |
| 2.054e-20 | -45.33 | LEE_BMP2_TARGETS_UP | MSigDB lists | LEE_BMP2_TARGETS_UP | 703 | 195 | 17758 | 2588 |
EXPH5,LTBP1,GAA,UNC93B1,ACACB,AGRN,ATP8A1,FAM102B,NDRG2,IL18,NENF,ITPR2,PLA2G16,SEPT4,MAP1LC3B,EPCAM,SESN3,NPNT,METTL7A,RGS3,AOX1,SERINC2,IRF2,CRY2,RAB20,NTN4,ARNT2,CPE,OLFML2A,SMARCA2,CITED4,USP18,CBX6,EZR,SLC17A5,SESN1,TCN2,ARHGEF26,EDNRA,TBC1D17,WIPI1,KCNK1,LRIG1,TRIM45,BMP1,RNASEL,WBSCR27,TRAF5,SLC31A2,RRAGD,GRN,CD99,PRSS8,BMF,ZNF395,ALDH6A1,MECOM,SPP1,CA2,FAM20C,COL6A1,DAPK1,C10orf54,ACAD8,CTSD,MYLIP,IGSF3,EPHX1,DDB2,PRSS23,MAPKAPK3,ADCK3,PARD3B,DCHS1,PDE5A,CYFIP2,FRMD4B,SCARB2,NAAA,H1F0,PELI2,MATN2,APPL2,RAB31,CTSA,MAL2,PLD1,PLIN3,PER3,SERPINB1,IFIH1,RUSC1,DMPK,REPS2,ST14,SLC2A8,THRA,DDIT4L,CAST,CD82,HDAC11,DGKA,COL18A1,P2RX7,SLC7A2,OSR2,DDR1,EMP2,CYP39A1,TMPRSS4,IER3,APOBEC3B,PDGFA,CDH1,VAT1,GLB1L2,NOTCH3,ACSL4,TSPAN1,CTDSP2,NAGA,PSRC1,C6orf1,TIMP2,COL6A2,KIAA0040,SLC39A8,SAT1,CLSTN1,ATP1B1,TMTC2,ALCAM,H2AFV,FZD7,GABARAPL1,TAPBP,WFS1,HAGHL,PDXK,RPL22,ABCA1,MAMDC2,GSDMD,FBLIM1,PLSCR4,PINK1,IGFBP6,RBM24,FAM189A2,CTSB,ESRP1,DAP,BLVRB,EPS8,SDC4,FLOT1,ARL4C,EFHD2,FZD6,H1FX,TMCC3,DTX3L,RNF128,MLPH,ITGB8,BMP7,KANK2,KLF9,AK3,ITM2C,GCNT1,P2RX4,NFE2L3,SUN2,OPLAH,FBLN5,PLSCR1,TEF,PIK3R1,COL7A1,NPDC1,LEPR,CRISPLD2,FUCA1,BTG1,PROM1,NR1D2,NMI,SPINT2,ABCB1,DTX4,OTUB2,LRRK1,TBC1D4,RGMA |
| 2.992e-20 | -44.96 | kidney | COSMIC cancer mutations | kidney | 16177 | 2467 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,DPP8,FAM46C,SPSB1,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,OXCT1,PHF7,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ASCL5,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,CARHSP1,PLCG1,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,KIAA0040,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,CAPN12,GPR107,REPS2,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,HN1L,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 4.145e-20 | -44.63 | positive regulation of biological process | biological process | GO:0048518 | 5310 | 991 | 16441 | 2455 |
ACACB,TRIM24,GRIK2,TRIM5,PNPLA2,DNAJC3,HEXB,RET,CACNA2D2,XIAP,NRG2,IL18,MORF4L2,SYTL4,SNX9,BARD1,CARD10,LTBP3,PHF1,GRM5,TP73,NPM2,CALM2,DAPK2,ARHGAP42,PSMD1,RGS12,TGFBR3,ALDH1A3,DNM2,SEMA3G,PPP1CA,PIK3CD,TIAM1,TIPARP,NEK4,VPS11,SMARCA2,TNIP1,SH3BGRL,DSTN,SPRTN,TFAP2C,PRKAR2B,LOXL2,F12,ICMT,RNF19B,ARF4,LCP1,ABR,PIAS3,PGF,PLCG1,MID1IP1,DNM1L,ANKRD6,LIMK1,MYLK,NOD2,MAP3K11,AGFG2,HDAC1,TMOD2,RNASEL,ITPKA,ARF6,HSPB1,STARD13,E2F8,GAB1,HOXC13,SCN5A,GGA1,ITGA6,SOX9,MERTK,LMNA,ELF3,TFAP4,RAC2,WDFY1,MEGF8,FLRT3,FAM13B,RANBP1,NEK2,MAP3K9,SLAIN2,MYDGF,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,MAPKAPK3,SALL4,STAT4,PYM1,SHARPIN,FHL2,MYBL2,CALCRL,PLS1,KIF20B,ELK1,ILK,TP53INP2,PSMA4,RHOB,PLIN5,STK17A,NCOA3,FNTA,ETS2,HTT,SEMA4D,SETD3,ITPR1,OSMR,AURKA,OSCP1,STK39,GDF11,ARPC2,CFAP20,TRPC3,RPS6KA3,TMEM173,RUSC1,XDH,DOCK9,DMPK,ARHGAP11A,GRHL2,NQO1,LFNG,INPP5D,RGS20,PKP2,MGST2,MVB12B,PRKACA,APC2,TNFSF9,CCND1,ST5,RNF220,CDH1,SP100,SH3BP1,DACT1,TAX1BP3,RTKN2,ACSL4,RAB27B,RASGEF1A,MYT1,ETV4,ENPP4,PSRC1,RIPK2,LGALS8,FZD4,PFKFB2,SYNE2,VPS4B,CDCA2,NUSAP1,PXYLP1,GTF2A2,EBF2,NFIX,IRS2,CDK19,WFS1,CORO1C,AXL,SIPA1L1,WWTR1,PLEKHG1,RGS14,GEN1,ARNT,MAPK12,CTHRC1,TCAF1,FARP1,TNRC6C,TAOK2,NKX3-1,HSP90B1,CKAP2,TRAF2,BIK,SDC4,FLOT1,BTN3A1,PDIA3,PKN1,HDGFRP2,ETS1,GSTP1,ARHGEF40,TSPAN17,NFAT5,SRPX2,ICAM1,NEO1,CTNNBIP1,CXCL16,ANK1,PDCD10,ITGB8,IRAK1,CTSC,KNDC1,GPC3,MCF2L,FAM20B,CST3,TUBGCP6,BAX,PLEKHF1,IGFBP2,MAPK11,RAG1,ITM2C,S100A6,PLSCR1,FMN1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,UBE2A,RAB3IP,ABLIM2,TXK,CNTNAP1,PITX2,BTG1,LDLRAP1,PROM1,ATXN7L3,NR1D2,ACVRL1,SYT7,DBI,NR4A3,ARFGAP3,ITGAV,HMGA1,CENPE,FHL1,OSR1,CD81,USF2,SHOX2,FOXA1,UNC93B1,ILDR1,AGRN,EPAS1,CNOT8,CUL4B,EPHA4,SUDS3,ARFGEF1,LMCD1,DNAJB11,F11R,NENF,ITPR2,HDAC6,PDGFB,SDC1,SPTB,FANCI,TFAP2E,PCNA,RPS6KA2,CTNNB1,RABEP2,NPNT,SHC3,P4HB,IL6ST,ARL1,PSMC2,DDHD2,MITF,ELF5,PASK,TNFRSF18,RGS5,SCARA3,MYBL1,S100A13,SMAGP,ZNF462,PLK1,THRB,PCGF5,CD55,CITED4,NFE2L1,CR2,EZR,KLK6,EAF2,PRKRA,CDK1,VCP,RHEB,OPTN,IRX3,DPYSL3,KDM4D,PLEKHG6,TBC1D17,KLF12,AGPAT2,PRKCDBP,KLF11,PIEZO1,MAFF,RRAGD,PRKAA2,PRSS8,RUNX2,BMF,LGALS3,DNAJB2,RASA2,PSMD7,SORBS3,RACGAP1,NCKAP1,DOCK11,FBLN1,IL18R1,ANO1,CORO1B,BMP2,TNS3,RB1,VASP,DAZAP1,TIMP1,IGF1R,RINL,GATA2,PAK2,TBCD,MDFIC,PIM1,NTN1,WNT3A,PLCB2,PSMA5,RGMB,SPATA13,STRADB,SCRIB,BCL2L13,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,CSF1,NLRC5,ATP1B3,SEMA3A,CTBP1,RNF146,RAD21,AVPI1,NF2,HOXB7,UPF3B,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,CCNL1,LPIN3,STIL,EMP2,BCAP31,SYTL2,RAD23A,IER3,PDGFA,SRPX,LMO4,PLCG2,BCL6,PLK4,CDH3,ESPN,NOTCH3,TMEM64,LMAN1,EGLN3,GM2A,DVL2,SULF2,CTH,PPIF,SIRT1,CLCN3,TIMP2,TCEB2,AKT1,S100A4,CDC20,SERTAD3,PTGER4,DAG1,PTGS2,DNAJC10,PTPRJ,ATP1A1,IDE,RBL1,MMP17,PSMD3,PTK7,XRCC3,CHMP4B,EFNA5,IRF7,ARHGAP4,CNEP1R1,ARFGEF3,BIN1,PINK1,MACC1,ADGRG1,CD63,TAB3,DAP,CTSB,GNAL,SELL,PSMD10,GDF15,HMGN3,JAG2,CRABP2,PARM1,PPP2R3A,NRP2,GBX2,GTF2F2,TFAP2A,SGK1,IL17RA,TRIM21,BUB1,SYK,CAMK2G,FAM134C,TLE6,DUSP1,NFE2L3,P2RX4,HES1,RHOA,HMGN5,PSMB4,NR3C1,PLAUR,CRIP2,LITAF,PPARA,PRICKLE1,MAML2,TRIM35,CAPNS1,BCAR1,BBS2,MAPK8IP1,BCL10,CD83,CNOT2,DDAH1,BANK1,TWSG1,SCG2,CDCA7L,NMI,FGF18,E2F1,PPP2R3C,PKD2,ICOSLG,NDFIP1,UBE2C,TBC1D4,ARHGEF9,ARHGEF4,LAMP1,TXN,ACVR1,LGR4,ATP8A1,CUL1,GATA3,PSME1,CAMK1D,CCNB1,SEPT4,SLC20A1,ELMOD2,RIC1,PICK1,NCS1,PAK6,HELZ2,CYP1A1,CTGF,STIM1,ELMO2,ZFP36,RGS3,IL31RA,FOSB,SERINC2,PIK3CA,IRF2,TACSTD2,TFG,PACSIN1,ACVR1C,CASP9,BNIP3L,NBPF3,AURKB,SAV1,LDB2,SLC25A5,POR,RAB2B,ARHGEF26,AHRR,AREG,PLK2,SH2D3C,TBX1,PPP2R4,NKD1,FAM110C,BMP1,MAPK13,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,KLF2,CDKN1C,SCOC,DHPS,TBC1D1,THEMIS2,HLA-E,PRKAA1,SLC25A27,KIF23,SLC1A3,NOTCH2,TNFRSF19,PSIP1,KIAA1161,MECOM,CALR,C9orf69,ITGA3,RALGPS2,CYR61,SNX18,PIK3AP1,MSH2,DAPK1,SORL1,TNFRSF12A,CACNA1D,TSPAN33,GPR161,EEF1D,RIMS2,SOCS5,EPB41L5,KLK5,MMD,MFI2,TBC1D8B,MICB,CALM1,AMER1,ANO6,PIP4K2C,WHSC1,KCTD20,EPHA1,CYFIP2,KDM3A,NFIB,RASA1,STX3,FAS,MMP15,SERTAD2,PRKAG2,PELI2,PIAS2,ARAP1,FAM83D,FGD6,NR4A2,KLK7,EFNA1,MAP3K5,IFIH1,EHD1,IRF1,PLEKHG3,SPRED1,FOXO6,ARMCX3,DLGAP5,THRA,RPS6KA1,IQGAP1,NDRG1,SUZ12,RALBP1,CD274,EGR3,BCL2L1,AIFM2,FLT3,MNS1,EPM2A,EPS8L2,CD46,NOV,CCNA2,ACAP2,RALB,CDKN1B,DAB2IP,PDE4D,IFIT1,OSBPL7,LGMN,TSPAN1,FLOT2,NR2C1,MED30,TMBIM1,TBC1D10B,SEMA3B,DOCK4,CDKN2AIP,FOXJ2,DMTN,UTRN,CLSTN1,PRKCQ,SLC11A2,ATP1B1,PYGO1,CBL,ITPR3,FZD7,FYN,JAK1,PPP2R5A,NGFRAP1,STK26,KIAA1804,TRIOBP,STAT1,SLC27A1,KLF5,NRG1,RAB29,COBL,ATMIN,DENND5B,PRKAR1A,WASF3,ARHGEF3,PCOLCE,DEPDC1,EPS8,NES,CBLL1,PBX3,PLD2,EFNB1,FGF19,TEAD3,ADGRB2,HLA-A,SIX4,WWP2,E2F7,OXCT1,RNF128,PTEN,PRC1,SGK3,SLC44A2,ERCC2,ERBB3,CITED2,CNOT6L,MAP3K7,GFI1,CNPY3,TRIM62,SPRY2,OSGIN1,MSH6,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,ARAP2,ARHGEF28,CASK,DENND1B,TEF,VAMP3,FURIN,YES1,GRTP1,FOS,GPLD1,CRTC2,RGS9,FGFR2,RCBTB2,PRDX3,RIN3,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,FZD5,ARSB,ESPL1,MELK,USP16,RGMA,JARID2,EXPH5,CCNC,CASP3,CAMKK1,CACNB4,ERP29,DENND2D,ARHGEF10L,EPCAM,SIPA1L2,RAB15,HSF2,GRHL1,ARHGEF37,CDKL5,SIVA1,TSPAN6,DPYSL2,DLG1,CAPG,AKR1B1,TRPC1,ASH2L,RP2,ARNT2,CTTN,SLC39A10,MYRIP,RASGRP1,CYP1B1,NLRP4,SOD1,CXXC5,TRIM8,ASXL1,ITCH,RNF165,ARHGDIB,STK17B,EDNRA,SEC14L2,MDK,ARHGEF19,GPRC5B,HPSE,MADD,CAB39,ADIPOR1,SP6,NRGN,RAP1GAP,PSMC1,PPP2R5D,CAPN1,NR2C2,GRN,LASP1,PIFO,ARAP3,SERPINE2,PPP1R12A,BVES,ETV5,ASB9,CALM3,TEC,ADAMTSL4,DUSP5,SPP1,CA2,NOXA1,FAM20C,OCRL,KCNN4,PRKCI,SUCO,EBF4,FNIP1,BRAT1,NPTN,C10orf54,ZRANB1,ALS2CL,CCDC88A,MDFI,ELK3,HMG20B,PDE5A,FBXO8,EGFR,GNAS,BCAR3,NUDT16,TSC1,ONECUT1,INSR,PLPP3,TMEM30A,CDCA5,NFKBIA,SH3BP4,DCUN1D1,EGFL7,CTSA,JAK3,TOB1,COL16A1,RARG,KLF7,DRD1,PROM2,SORBS1,PAX6,IL15,PSME2,COL18A1,IL27RA,OSR2,MICALL2,PHLDA1,ARHGEF16,SS18,ARTN,KIF14,SMO,ZBTB49,TWIST1,DIXDC1,STEAP3,ECE1,EPB41L4B,NFKB2,F2R,HSPA2,UPF3A,FRS3,CHP1,MAP3K3,SOAT1,BAG4,RFK,ERBB2IP,DUSP4,CD40,DOCK5,MAP3K6,ARHGAP35,SOCS3,JADE1,HSF4,BHLHB9,STAT6,SECTM1,TLE1,OVOL1,CANT1,SPTBN5,AKNA,ABCA1,LIFR,GLIS3,ANXA3,GCLM,TSPAN15,ARHGEF11,CIT,SH3D19,ARHGEF7,SERPINB9,LRP4,TGFBR1,AES,TRIB2,SBF1,ITGA2B,HDAC9,SYDE2,IRF2BPL,KIF5B,TOP2A,SNX13,CARD8,ADORA1,ADRBK1,LLGL2,BMP7,TOX2,ZDHHC13,ACTA2,H2AFY,BRD7,IQGAP3,RPGR,SUN2,DCAF6,ADAM17,RAB3B,WNT10B,ASPM,NR4A1,GCLC,RC3H2,RGCC,RUNX3,MPV17L2,MAP1B,CTSL,ARHGAP24,HLA-B,CD8A,CASP7,SWAP70,RAP2C,DTX4,UBE2D2,TADA2B,ARRB1,SOX8,ZMIZ1,AHR,L1CAM,RAB3IL1,ABCG1,NGEF |
| 1.145e-19 | -43.61 | regulation of cell communication | biological process | GO:0010646 | 2931 | 601 | 16441 | 2455 |
TRIM24,GRIK2,TRIM5,RET,CACNA2D2,XIAP,NRG2,IL18,SYTL4,KIF26A,CARD10,GRM5,TP73,CALM2,DAPK2,PSMD1,RGS12,TGFBR3,CABP1,DNM2,CRY2,PPP1CA,TIAM1,TNIP1,SH3BGRL,PRKAR2B,ICMT,PNKD,ABR,ENPP1,PLCG1,GRID2IP,DNM1L,ANKRD6,TRAF3IP1,NOD2,MAP3K11,HDAC1,TMOD2,ITPKA,ARF6,HSPB1,STARD13,GAB1,NUAK1,ITGA6,SOX9,RAB23,ZNRF3,LMNA,TFAP4,RAC2,WDFY1,RIMS3,FAM13B,MAP3K9,MYDGF,CNGA1,NCAM1,MAPK7,MAPKAPK3,SHARPIN,NPHP3,ILK,PSMA4,RHOB,PLIN5,NCOA3,FNTA,HTT,SEMA4D,ITPR1,GDF11,RUSC1,XDH,DMPK,ARHGAP11A,LFNG,INPP5D,RGS20,GRK6,MVB12B,PRKACA,APC2,CCND1,ST5,RNF220,SP100,DACT1,TAX1BP3,RASGEF1A,CDKN2D,MYT1,RIPK2,FZD4,PFKFB2,SYP,IRS2,WFS1,SLC9A6,AXL,WWTR1,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,RGS14,ARNT,CTHRC1,FARP1,TAOK2,NKX3-1,TRAF2,BIK,FLOT1,PDIA3,PKN1,KCNC4,GSTP1,ARHGEF40,TSPAN17,NFAT5,ICAM1,NEO1,CTNNBIP1,PDCD10,IRAK1,CTSC,GPC3,MCF2L,BAX,PLEKHF1,TMBIM6,IGFBP2,MAPK11,ITM2C,PLSCR1,BCL9,RAPGEF2,PIK3R1,GRIN1,PIM3,TXK,CNTNAP1,LDLRAP1,ACVRL1,SYT7,DBI,ITGAV,CD81,SHOX2,FOXA1,SIGIRR,ILDR1,TNK1,AGRN,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,ITPR2,HDAC6,PDGFB,SPTB,CTNNB1,NPNT,SHC3,P4HB,IL6ST,PSMC2,PASK,DUSP10,TNFRSF18,RGS5,S100A13,CD55,EZR,TNFAIP8L1,KLK6,PRKRA,SESN1,CDK1,RHEB,OPTN,PLEKHG6,KCNMB4,AGPAT2,RAB11FIP1,PRKCDBP,CTNND1,POMT1,RRAGD,PRKAA2,RUNX2,BMF,LGALS3,RASA2,UBASH3B,PDCL,PSMD7,SORBS3,RACGAP1,DHRS3,FBLN1,IL18R1,ANO1,SSX2IP,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,MDFIC,WNT3A,PSMA5,CYP26B1,SPATA13,STRADB,G2E3,NMT2,CDK5R1,MAPKAPK2,CSF1,NLRC5,IFI6,RNF146,AVPI1,NF2,FOXM1,TP53,ERBB2,P2RX7,RASGRP3,EMP2,BCAP31,CYP26A1,PER2,CDK14,IER3,TTC21B,PDGFA,SRPX,BCL6,CDH3,DVL2,SULF2,CTH,SIRT1,PPIF,TIMP2,AKT1,FIGNL1,S100A4,CDC20,C3orf33,DAG1,PTGS2,PTPRJ,PSMD3,STK38,CHMP4B,EFNA5,IRF7,ARHGAP4,ZC3HC1,ARFGEF3,PINK1,ADGRG1,CD63,TAB3,PSMD10,GDF15,HMGN3,JAG2,CRABP2,AIP,PPP2R3A,FZD6,CD109,CDK16,BUB1,FAIM,SYK,CAMK2G,DUSP1,P2RX4,HES1,RHOA,PSMB4,PLAUR,LITAF,PRICKLE1,STMN3,CARD19,PELI3,AKAP3,MAPK8IP1,BCL10,CNOT2,BANK1,TWSG1,SCG2,FGF18,NETO2,E2F1,PKD2,SPCS3,NDFIP1,HIPK3,ARHGEF9,ARHGEF4,ACVR1,TXN,LGR4,GATA3,PSME1,PJA2,SEPT4,SLC20A1,PICK1,PAK6,SESN3,CTGF,RGS3,IL31RA,KCNS3,TFG,RCAN3,METAP2,ACVR1C,PBK,BNIP3L,SLC35C1,SLC25A5,POR,ARHGEF26,ANKRD10,SLC25A4,PLK2,TBX1,SH2D3C,NKD1,FAM110C,EIF4EBP2,SPRY4,UNC5B,F2RL1,TRAF5,LZTS1,FGD1,SCOC,CDKN1C,PRKAA1,SLC1A3,NOTCH2,TNFRSF19,KIAA1161,MECOM,CALR,ITGA3,RALGPS2,CYR61,PIK3AP1,VASN,DAPK1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,GPR161,EEF1D,RIMS2,TSPAN33,SOCS5,QSOX1,KLK5,CALM1,AMER1,PIP4K2C,RASA1,STX3,FAS,PELI2,ARAP1,FAM83D,PIAS2,FGD6,NR4A2,EFNA1,MAP3K5,IRF1,PLEKHG3,SPRED1,TRIP10,NLRX1,THRA,IQGAP1,RALBP1,DDIT4L,BCL2L1,FLT3,EPM2A,EPS8L2,ZFYVE9,CD46,APLP2,NOV,RALB,DAB2IP,PDE4D,LGMN,FLOT2,NR2C1,TMBIM1,CDKN2AIP,DMTN,CLSTN1,PRKCQ,ITPR3,CBL,FZD7,FYN,JAK1,KIAA1804,STAT1,PPP1CB,NRG1,PRKAR1A,ARHGEF3,IGFBP6,EPS8,PLD2,FGF19,OXCT1,GNB5,PTEN,SLC44A2,ERBB3,MAP3K7,CITED2,GFI1,SPRY2,TRIM62,NCOA2,FARP2,TGIF1,RASGRF1,ARHGEF28,ARAP2,FURIN,VAMP3,FBXO9,GPLD1,RGS9,FGFR2,TBX18,RYK,GRIN2D,LRRK1,GPER1,FZD5,LTBP1,ERP29,SLC8B1,MAP1LC3B,KREMEN1,TRIM68,SH3KBP1,ARHGEF10L,SIPA1L2,ARHGEF37,TSPAN6,SIVA1,DLG1,AKR1B1,CTTN,SLC39A10,PTPRE,MYRIP,RASGRP1,CYP1B1,SOD1,TRIM8,CXXC5,ASXL1,USP18,ITCH,RNF165,ARHGDIB,CXXC4,ARHGEF19,GPRC5B,HPSE,MADD,ADIPOR1,RAP1GAP,PSMC1,LASP1,ARAP3,SERPINE2,PPP1R2,CALM3,PHLPP1,DUSP5,CA2,PFKL,FAM20C,KCNN4,OCRL,FNIP1,NPTN,C10orf54,ZRANB1,ALS2CL,MDFI,FBXO8,PDE5A,RANBP9,C3orf58,EGFR,GNAS,ONECUT1,TSC1,INSR,PLPP3,NFKBIA,SH3BP4,RHOBTB2,EGFL7,JAK3,AFAP1,TOB1,DRD1,SORBS1,IL15,PSME2,SOD2,ARHGEF16,KIF14,SMO,TWIST1,DIXDC1,APIP,F2R,FRS3,CHP1,MAP3K3,BAG4,KREMEN2,ERBB2IP,DUSP4,CD40,MAP3K6,SOCS3,ARHGAP35,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,ABCA1,GCLM,ARHGEF11,TSPAN15,ARHGEF7,LRP4,AES,TGFBR1,NOTUM,TRIB2,HMGXB4,SYDE2,KIF5B,SNX13,CARD8,ADRBK1,ADORA1,LLGL2,BMP7,ZDHHC13,KANK2,IQGAP3,MYO5A,RAB3B,ADAM17,WNT10B,GCLC,ASPM,RC3H2,SYBU,FOXL1,ARHGAP24,LEMD2,CD8A,PRCP,UACA,ARRB1,L1CAM,NGEF |
| 1.275e-19 | -43.51 | regulation of response to stimulus | biological process | GO:0048583 | 3566 | 707 | 16441 | 2455 |
TRIM24,GRIK2,TRIM5,DNAJC3,RET,XIAP,NRG2,IL18,KIF26A,CARD10,GRM5,TP73,CALM2,DAPK2,ZYX,PHYHIP,PSMD1,AP1M2,RGS12,TGFBR3,DNM2,CRY2,SEMA3G,PPP1CA,PIK3CD,TIAM1,APOBEC3G,NEK4,TNIP1,SH3BGRL,F12,ICMT,MYOM1,ABR,ENPP1,PLCG1,DNM1L,ANKRD6,LIMK1,TRAF3IP1,MYLK,NOD2,MAP3K11,HDAC1,TMOD2,RNASEL,ARF6,HSPB1,STARD13,GAB1,SCN5A,NUAK1,ITGA6,SOX9,RAB23,ZNRF3,LMNA,TFAP4,RAC2,ZCCHC17,WDFY1,MEGF8,FAM13B,MAP3K9,USP1,ALPK1,MYDGF,CNGA1,NCAM1,MAPK7,NUP85,MAPKAPK3,SHARPIN,CALCRL,ELK1,NPHP3,ILK,PSMA4,RHOB,PLIN5,PTPRF,IL1R1,NCOA3,FNTA,HTT,SEMA4D,ITPR1,OSMR,MDH1,STK39,GDF11,ARPC2,CFAP20,TRPC3,NUP58,RPS6KA3,TMEM173,RUSC1,XDH,ARHGAP11A,LFNG,INPP5D,RGS20,GRK6,MVB12B,PRKACA,APC2,CCND1,ST5,RNF220,CDH1,SP100,DACT1,TAX1BP3,RASGEF1A,CDKN2D,MYT1,RNF169,ENPP4,RIPK2,FZD4,SYP,IRS2,CDK19,WFS1,SLC9A6,AXL,SIPA1L1,WWTR1,PLEKHG1,INPP4B,TRABD2A,RGS14,ARNT,CTHRC1,FARP1,TNRC6C,NKX3-1,TAOK2,HSP90B1,TRAF2,BIK,FLOT1,BTN3A1,PDIA3,PKN1,ETS1,GSTP1,ARHGEF40,TSPAN17,NFAT5,ICAM1,NEO1,CTNNBIP1,PDCD10,IRAK1,CTSC,GPC3,MCF2L,BAX,PLEKHF1,TMBIM6,IGFBP2,MAPK11,ITM2C,PARP9,PLSCR1,BCL9,RAPGEF2,PIK3R1,GRIN1,PIM3,TXK,CNTNAP1,LDLRAP1,ACVRL1,NR1D2,SLC35B3,NR4A3,ITGAV,HMGA1,NUP37,CD81,SHOX2,FOXA1,SIGIRR,UNC93B1,TNK1,AGRN,EPHA4,ARFGEF1,LMCD1,NDRG2,NENF,ITPR2,HDAC6,PDGFB,SPTB,PCNA,NUP210,RPS6KA2,CTNNB1,NPNT,SHC3,P4HB,IL6ST,PSMC2,DUSP10,TNFRSF18,RGS5,SCARA3,S100A13,SMAGP,CD55,CR2,EZR,TNFAIP8L1,KLK6,PRKRA,SESN1,CDK1,RHEB,OPTN,KDM4D,PLEKHG6,AGPAT2,PRKCDBP,CTNND1,POMT1,TC2N,RRAGD,PRKAA2,RUNX2,BMF,LGALS3,HLA-F,RASA2,UBASH3B,PDCL,PSMD7,SORBS3,RACGAP1,NCKAP1,FBLN1,DHRS3,IL18R1,ANO1,SSX2IP,CORO1B,BMP2,RB1,VASP,TIMP1,IGF1R,GATA2,PAK2,MDFIC,WNT3A,PSMA5,CYP26B1,SPATA13,STRADB,EIF2AK1,G2E3,NMT2,CDK5R1,MAPKAPK2,PVRL2,PHLPP2,CSF1,NLRC5,SEMA3A,IFI6,RNF146,AVPI1,NF2,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,SLC7A2,EMP2,BCAP31,CYP26A1,CDK14,IER3,TTC21B,PDGFA,SRPX,PLCG2,BCL6,CDH3,DVL2,SULF2,CTH,SIRT1,PPIF,TIMP2,ERLEC1,AKT1,FIGNL1,S100A4,PTGER4,C3orf33,DAG1,PTGS2,PTPRJ,PSMD3,STK38,CHMP4B,EFNA5,IRF7,ARHGAP4,ZC3HC1,ARFGEF3,PINK1,CD63,ADGRG1,TAB3,CTSB,SELL,PSMD10,GDF15,HMGN3,JAG2,CRABP2,AIP,FZD6,PPP2R3A,CD109,CDK16,UBE2J1,IL17RA,BUB1,FAIM,SYK,CAMK2G,DUSP1,P2RX4,HES1,FBLN5,RHOA,PSMB4,PLAUR,LITAF,PPARA,PRICKLE1,STMN3,CARD19,FXR2,AKAP3,PELI3,BCAR1,BBS2,MAPK8IP1,BCL10,CNOT2,BANK1,TWSG1,SCG2,NMI,FGF18,NETO2,E2F1,PPP2R3C,PKD2,NDFIP1,HIPK3,ARHGEF9,ARHGEF4,LAMP1,TXN,ACVR1,LGR4,TAP1,GATA3,CUL1,PSME1,CAMK1D,PLXNA1,PJA2,VASH1,SEPT4,SLC20A1,ELMOD2,PAK6,SESN3,CTGF,ELMO2,RGS3,IL31RA,PIK3CA,RCAN3,TFG,METAP2,PBK,CASP9,BNIP3L,SLC35C1,AGO4,SLC25A5,POR,ARHGEF26,ANKRD10,PLK2,TBX1,SH2D3C,NKD1,FAM110C,MAPK13,SPRY4,UNC5B,F2RL1,TRAF5,LZTS1,FGD1,DDX58,SEMA6B,CDKN1C,SCOC,THEMIS2,HLA-E,PRKAA1,SLC1A3,NOTCH2,TNFRSF19,KIAA1161,MECOM,CALR,ITGA3,RALGPS2,CYR61,PIK3AP1,VASN,PRKG1,DAPK1,SORL1,TNFRSF12A,PIKFYVE,GPR161,EEF1D,TSPAN33,SOCS5,QSOX1,KLK5,MICB,CALM1,AMER1,ANO6,PIP4K2C,WHSC1,CYFIP2,RASA1,STX3,FAS,PELI2,ARAP1,FAM83D,PIAS2,FGD6,KLK7,NR4A2,EFNA1,PER3,MAP3K5,IFIH1,IRF1,PLEKHG3,SPRED1,TRIP10,NLRX1,THRA,RPS6KA1,DDIT4L,RALBP1,BCL2L1,FLT3,EPM2A,EPS8L2,ZFYVE9,CD46,APLP2,NOV,FAM46A,RALB,CDKN1B,DAB2IP,PDE4D,IFIT1,LGMN,FLOT2,NR2C1,TMBIM1,SEMA3B,CDKN2AIP,DMTN,PRKCQ,ATP1B1,CBL,ITPR3,FZD7,FYN,JAK1,STK26,KIAA1804,STAT1,PPP1CB,NRG1,ARHGEF3,IGFBP6,EPS8,HERC5,PLD2,FGF19,HLA-A,OXCT1,GNB5,PTEN,SLC44A2,ERBB3,CITED2,MAP3K7,CNPY3,GFI1,TRIM62,SPRY2,MSH6,NCOA2,FARP2,TGIF1,RASGRF1,CASK,ARHGEF28,ARAP2,MPP1,FURIN,VAMP3,FBXO9,YES1,FOS,GPLD1,RGS9,FGFR2,TBX18,RYK,ERAP1,GRIN2D,LRRK1,GPER1,FZD5,LTBP1,CACNB4,ERP29,MAP1LC3B,KREMEN1,TRIM68,SH3KBP1,HTR1D,ARHGEF10L,SIPA1L2,ARHGEF37,TSPAN6,SIVA1,DLG1,AKR1B1,CTTN,SLC39A10,PTPRE,RASGRP1,CYP1B1,SOD1,CXXC5,TRIM8,ASXL1,ITCH,USP18,RNF165,ARHGDIB,CXXC4,MDK,ARHGEF19,GPRC5B,HPSE,MADD,ADIPOR1,RAP1GAP,PPP2R5D,PSMC1,LASP1,ARAP3,PPP1R2,SERPINE2,CALM3,TEC,PHLPP1,DUSP5,SPP1,FAM20C,OCRL,KCNN4,FNIP1,NPTN,C10orf54,HLA-C,ZRANB1,ALS2CL,MDFI,FBXO8,PDE5A,C3orf58,RANBP9,EGFR,GNAS,FECH,NUDT16,ONECUT1,TSC1,INSR,PLPP3,NFKBIA,SH3BP4,RHOBTB2,EGFL7,YOD1,JAK3,TOB1,AFAP1,DRD1,SORBS1,IL15,PSME2,SOD2,IL27RA,ARHGEF16,ARTN,KIF14,SMO,TWIST1,DIXDC1,APIP,NFKB2,F2R,FRS3,CHP1,MAP3K3,BAG4,KREMEN2,ERBB2IP,DUSP4,CD40,MAP3K6,CASP4,ARHGAP35,SOCS3,STAT6,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,PLXND1,ABCA1,GCLM,ARHGEF11,TSPAN15,ARHGEF7,SERPINB9,LRP4,TGFBR1,AES,NOTUM,TRIB2,HMGXB4,SYDE2,SNX13,CARD8,ADORA1,ADRBK1,LLGL2,BMP7,ZDHHC13,KANK2,IQGAP3,MYO5A,ADAM17,WNT10B,ASPM,GCLC,NR4A1,SYBU,RC3H2,RGCC,FOXL1,LEMD2,ARHGAP24,CTSL,HLA-B,CD8A,SWAP70,PRCP,UBE2D2,UACA,ARRB1,L1CAM,CD33,NGEF |
| 1.852e-19 | -43.13 | GOZGIT_ESR1_TARGETS_DN | MSigDB lists | GOZGIT_ESR1_TARGETS_DN | 691 | 190 | 17758 | 2588 |
TRIM2,TSC22D3,EPHA4,MCOLN3,RET,LMCD1,GATA3,PDGFRL,PLA2G16,CACNB4,SIPA1L2,SESN3,CYP1A1,RPS6KA2,NPNT,ELF5,MITF,AOX1,POF1B,ATRNL1,DUSP10,SNX16,TACSTD2,CPE,RASGRP1,CYP1B1,PCGF5,CELSR2,SH3BGRL,USP18,KDELR3,PLEKHB1,PIAS3,PLCH1,ENPP1,AREG,WIPI1,MAP2,PLK2,FAM114A1,NFKBIZ,TTC9,TANC2,LSM14B,TC2N,HOXC13,CD99,PRSS8,RUNX2,FAM169A,NUAK1,ITGA6,SOX9,ASB9,SAMD9,HERC6,DHRS3,LMNA,B3GALNT1,IGF1R,TIMP1,SLC16A6,FLRT3,FRAS1,AIM1,RUNDC3B,TMEM8A,FAR2,SLC12A2,GAD1,MAST4,CKAP4,ABCC1,EPHX1,EPB41L5,SLC37A1,PRSS23,MICB,SPATA13,PDK3,NPC2,IFIT3,NUDT16,PVRL2,LTBP2,SHROOM2,IFI6,KLF7,NCKAP5,ARMCX3,NF2,GRHL2,PAPSS2,ATP2C2,COL18A1,FTH1,EGR3,SLC7A2,FAM198B,OSR2,TMPRSS4,SYTL2,KCTD15,SCNN1A,FAM46A,TRANK1,SP100,BCL6,VAT1,TWIST1,IFIT1,TMEM64,EGLN3,TSPAN1,RAB27B,LOXL1,MX1,TMTC1,TIMP2,LGALS8,SLC39A8,SAT1,UTRN,ATP1B1,TMTC2,ALCAM,GABARAPL1,ZNF641,SHROOM3,SECTM1,STAT1,INPP4B,MAOA,TLE1,IRF7,SLC25A30,ST3GAL1,PRKAR1A,CTHRC1,FARP1,FAM189A2,MPZL1,IGFBP6,SLC16A14,MACC1,TSPAN15,FRMD6,ATP9A,SCD5,SELL,GDF15,COL4A5,CRABP2,TRIB2,NUCB2,HDAC9,CD109,CXCL16,MLPH,ITGB8,SLC27A6,FUT8,SGK1,FAM102A,TSPAN13,KLF9,MYO5A,RBMS2,S100A6,CASK,LCA5,DENND1B,MBNL3,PLEKHA7,STMN3,AK4,BLVRA,LEPR,SERPINA1,FGFR2,RND3,NAT1,CDCA7L,PGM2L1,SH3BGRL2,CPEB2,SAT2,AHR,PKIA,FOXA1 |
| 2.073e-19 | -43.02 | organelle | cellular component | GO:0043226 | 12606 | 2035 | 17570 | 2579 |
HECA,IBTK,SLC25A13,PNPLA2,HEXB,RET,CCNO,TRAPPC8,TGOLN2,ISOC2,LACTB2,DPP8,SNX9,CMTM6,LTBP3,GRM5,ZNF275,NPM2,CDKN2C,NAPG,MUC4,UBE2T,ATP13A3,DNM2,CRY2,PPP1CA,WBP4,IL10RB,TIPARP,CPE,MGAT5,NEK4,DSTN,UXT,TMEM98,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,GINS4,LCP1,PIAS3,ENPP1,CARHSP1,PLCG1,MPRIP,MID1IP1,CELF5,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,HSPB1,STARD13,ANXA11,NXT2,SCN5A,GGA1,SEC61G,MTL5,RAB23,COX6C,FAM21C,TTYH3,MARCH8,TFAP4,FLII,RAC2,SH3D21,ZCCHC17,FRY,ATP5H,MEGF8,FLRT3,FBXO7,RANBP1,FBXL14,PCYOX1,SLAIN2,CADPS2,USP1,MYDGF,CNGA1,ZMYM1,MAPK7,MOXD1,MYLIP,NUP85,TTLL1,PPP6R1,MCCC2,REC8,PQLC3,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,GOLT1A,PSMA4,GNA11,SFXN5,PLIN5,IL1R1,FNTA,SLC4A4,ETS2,APMAP,S100A5,DGAT2,STK39,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,DMPK,TPRN,NQO1,LFNG,CD82,APOO,PTTG1,C5orf30,MAPK4,MGST2,MVB12B,MOCS1,APPBP2,RCN1,RBM23,MUC16,CDH1,XYLT2,TAX1BP3,ZNF365,MYT1,SNX10,ETV4,MX1,SNX8,SEC61B,ERMP1,COL6A2,RIPK2,APOBEC3D,AGPS,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,GTF2A2,SNX12,TRIM7,ZNF618,COX20,EBF2,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CCNB3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,MZT1,HSP90B1,GCAT,CKAP2,BACE1,TRAF2,DCAF7,ESRP1,BIK,SDC4,HABP4,FLOT1,CTSZ,ZNF219,HDGFRP2,IFT27,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,GPC3,MGAT4A,FAM20B,CST3,TUBGCP6,KLC3,BAX,IGFBP2,RAG1,MED22,PARP9,ACBD5,PVRL4,PLSCR1,TACC1,PIK3R1,DUSP23,MRS2,NUB1,UBE2A,PGBD1,AK4,RAB3IP,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,FAM3C,PLA2G15,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,WDR45B,SRSF9,ACOT7,PHC1,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,NDRG2,F11R,NENF,ITPR2,GALM,MGAT5B,SPTB,SLC9A3R2,FANCI,TFAP2E,PLS3,SUSD2,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,P4HB,IL6ST,ARL1,PSMC2,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KRT80,KCNIP3,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,CCBL2,CKAP2L,ARFRP1,EAF2,SESN1,DZIP1L,KDM4D,TNS4,TRIM9,HS6ST1,PLEKHG6,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,KPNA2,TC2N,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,PARP12,USH1C,LGALS3,HJURP,DNAJB2,FXYD3,PSMD7,SORBS3,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TIMP1,RINL,KIF13B,TBCD,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,USP31,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,PRX,NMT2,C18orf8,CDK5R1,FOXD2,FA2H,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,AKIP1,CDAN1,CCNB2,USP43,RAD21,HOXB7,CTDSPL,TP53,P2RX7,RHPN2,BAHD1,STIL,PCBP1,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,KMT5C,WDR44,TACC2,BCL6,PLK4,ZDHHC23,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,PTGS2,TAPBP,ZNF628,PTPRJ,IDE,PAFAH1B3,RBL1,STK38,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ST3GAL1,BTBD6,FAM134B,ARFGEF3,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CPEB4,TAB3,CTSB,SCD5,GNAL,MCTP2,CDCA8,ERCC6L,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,TBC1D31,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,HMGCL,SYK,ATP2B1,GCNT1,WBP5,DUSP1,NFE2L3,P2RX4,HES1,FBLN5,RHOA,HMGN5,GUSB,PLAUR,PRICKLE1,DPP9,STMN3,MAML2,GGH,COL7A1,TXNDC11,RNPEP,BBS2,USP6,BCL10,DDX23,CNOT2,DDAH1,SCG2,NEIL3,NIPSNAP3A,FGF18,E2F1,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,PKIA,GOLGB1,LAMP1,SLC35D2,TXN,PNISR,SSH1,HSPG2,TSC22D3,CUL1,PSME1,NANS,CAMK1D,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,PAK6,HELZ2,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,PALD1,FOSB,POLL,KCNS3,SERINC2,IRF2,SNX16,HYLS1,TACSTD2,MARCH2,ZBTB18,SGCE,SPATA18,CDYL,BNIP3L,SLC35C1,KIF13A,LDB2,POR,RAB2B,PRIM1,PPP2R4,PRDM5,BMP1,SERPINI1,NFKBIZ,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,PRKAA1,AKAP17A,TXNDC9,HERC6,APBA1,PDXDC1,PSIP1,SH3RF2,MESDC2,C9orf69,CALR,DOPEY2,ZNRF2,BHLHE41,RPL39,VASN,MSH2,DAPK1,TPST1,PRKG1,OSTF1,CYSRT1,CACNA1D,DLX4,ZNF117,SYTL3,GPR161,TRAK2,PIGC,GID8,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,CALM1,WHSC1,PYGL,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,WDR19,ZDHHC20,AGBL5,PIAS2,FAM83D,APPL2,ARAP1,SFMBT1,CABIN1,KLK7,SAMD8,ZBTB34,PLIN3,PER3,HOOK1,IFIH1,EHD1,FOXO6,SPRED1,KIF3C,TCF25,DLGAP5,TCTN2,GPR107,ST14,THRA,CERCAM,NDRG1,CCDC110,ATP2C2,FTH1,BCL2L1,FLT3,DDR1,CYP39A1,ZFYVE9,EPS8L2,EPM2A,APOBEC3B,CD46,NOV,CCNA2,ACAP2,RALB,RNASEH2A,PDE4D,EPHB4,OSBPL7,TSPAN1,SULT2B1,FLOT2,NAGA,MED30,SEMA3B,ATG4D,MSANTD4,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,CLSTN1,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,CBL,B3GALNT2,ITPR3,ALCAM,TRIQK,ATP10D,CEP162,ZMPSTE24,DDOST,ACAD10,NGFRAP1,TRIOBP,SLC27A3,CBX7,COBL,MAMDC2,PRKAR1A,PLSCR4,IGFBP6,DEPDC1,CENPI,EPS8,NES,CBLL1,PBX3,PLD2,FBXO6,SPDL1,DNAH3,EFNB1,COX7A2,HLA-A,WWP2,SCML1,SLC25A36,CKAP5,E2F7,GOLGA2P5,RNF128,GNB5,FUT8,DRAM1,CD9,CITED2,TTPA,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,PAPD7,ZC3H11A,TCFL5,ZKSCAN2,DIAPH2,UBAC1,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,CRTC2,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,RIN3,ABCB1,RYK,ERAP1,RABL6,LRRK1,WDR62,FZD5,ESPL1,DEF6,RGMA,CCNC,FAF2,UGT8,CRYM,UBE2Q1,VARS2,MPP5,COMMD5,MAP1LC3B,ERP29,SLC8B1,ECI1,TRIM68,EPCAM,ZFYVE16,RAB15,HSF2,CASC4,METTL7A,CDKL5,SIVA1,CEP78,TRPC1,ASH2L,CTTN,MYRIP,BTBD3,STK35,SP5,LAMP3,CERS2,CYP1B1,NLRP4,CXXC5,CENPA,ASXL1,LAP3,ITCH,ACBD3,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,TDRD7,SH3GLB2,CAB39,ZNF165,SP6,GLA,CHPT1,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,ZNF395,SERPINE2,PPP1R12A,ETV5,ASB9,ABCG2,CALM3,PM20D2,TEC,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,SPP1,CES2,FAM20C,PFKL,OCRL,COL6A1,SUCO,PRKCI,SRP54,BRAT1,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNED1,MDFI,SNX7,TPGS2,ELK3,SPA17,VWA1,KIAA1109,PRRC1,NUBP1,PDIK1L,C3orf58,STEAP1,RANBP9,SOX13,INSR,UAP1,TMEM30A,SH3BP4,SPAG7,RAB31,DCUN1D1,CTSA,DONSON,SHROOM2,JAK3,TOB1,APOL2,COL16A1,RARG,AFAP1,SNX30,DRD1,LMO7,CCNE2,DYNLRB1,SORBS1,PAX6,FAM214B,HDAC11,SOD2,PDIA5,COL18A1,MRAS,OSR2,SAYSD1,PHLDA1,EXT2,MXD1,SAP130,ZNF687,CYP4F11,COX14,KIF14,REEP1,ZBTB49,ECE1,EPB41L4B,NFKB2,ETHE1,UPF3A,EBAG9,CHP1,SEPHS1,SOAT1,RFK,C3orf52,MRPS35,GLO1,TMTC2,CD40,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,HSF4,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,PTBP3,SPTBN5,MAD2L1BP,ABCA1,KDELC2,GLIS3,FBLIM1,ENO2,TSPAN15,CIT,SHPRH,SH3D19,ARHGEF7,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,TMEM63A,KIF5B,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ZDHHC13,ACTA2,ARVCF,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,MYO5A,B3GALT6,PGM1,DCAF6,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,NDRG3,TCEAL8,FOXL1,ENDOD1,LEMD2,ARHGAP24,CTSL,CASP7,SWAP70,RND3,TRIM69,CTSV,RAP2C,CSGALNACT1,UACA,ARRB1,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,CD33,ABCG1,DOC2A,ACACB,KLK10,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,SMARCAL1,MMADHC,FBXO2,XIAP,DHX8,LGI3,LYNX1,IL18,CNTROB,MORF4L2,SYTL4,BARD1,KIF26A,PHF1,EPDR1,TP73,CALM2,DAPK2,WEE1,ZYX,PQLC2,PSMD1,AP1M2,TGFBR3,RGS12,DNAH6,CABP1,CYP2S1,ALDH1A3,RDH14,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,MANF,PIK3CD,TINAGL1,ODF2L,APOBEC3G,ERAP2,TUBA4A,SPEF2,VPS11,SMARCA2,TNIP1,SERTAD4,SH3BGRL,SPRTN,RNF11,MTRF1L,LOXL2,F12,ICMT,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,SERPINB6,MRPS28,RELL1,ARF6,E2F8,PDPR,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,CYP2J2,SOX9,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,DNPEP,WDFY1,CD22,PRICKLE4,ZIC5,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,NAGPA,UFD1L,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,ILK,MEST,TP53INP2,SPTLC2,RHOB,DCP2,CYB5A,STK17A,DHX32,PTPRF,NAAA,NCOA3,SCARB2,MTFMT,TIMM8A,HTT,SETD3,TEX30,ITPR1,AURKA,DYSF,MDH1,ALG2,B4GAT1,MAL2,NDE1,DRP2,ARPC2,ZNF502,SERPINB1,RPS6KA3,CSRP2,XDH,EGLN1,MTM1,CCDC109B,GRHL2,TMSB15A,TUBB4B,GALNT12,ACTR8,ETNK1,RGS20,WDTC1,TESK2,PKP2,NUF2,PRKACA,APC2,KTN1,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,RNF169,ENPP4,CAMSAP3,SSH3,PSRC1,LGALS8,NRBF2,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,PXYLP1,RAB38,PEX5,STX10,SLC9A6,WWTR1,SIPA1L1,TRABD2A,PDXK,RGS14,GEN1,ARNT,TTC8,GALK1,FARP1,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,PDIA3,GMCL1,PKN1,TMA16,NUCB2,ETS1,GSTP1,HOXB2,TIPRL,ICAM1,NEO1,PDIA4,DTX3L,CAPN2,ANK1,ADD3,IRAK1,CTSC,ARSG,ANKS1B,ALG13,CALD1,FDXR,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,ZNF230,MAPK11,AK3,SGCB,ITM2C,TPCN1,S100A6,TMX1,CRTAP,POU6F1,MOB4,AMOTL2,LCA5,NUDT8,FMN1,CTNNAL1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,PLEKHA7,DBR1,BLVRA,NEURL1B,FAM109A,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,GALNT3,PITX2,BTG1,KIAA0141,CCDC6,ATXN7L3,NR1D2,ZFP30,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,CYBRD1,FOXA1,MYL9,UNKL,UNC93B1,AGRN,GNPDA1,CUL4B,EPHA4,SUDS3,MCCC1,NDC80,CDIPT,HDAC6,PDGFB,NUP62CL,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,ELF5,DUSP10,PXMP4,TLN2,TRAM1,MYBL1,DDX59,NEB,S100A13,CCDC38,ZNF462,PCGF5,CD55,ING1,HN1L,CITED4,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,RHEB,OPTN,IRX3,DPYSL3,PLCH1,MFAP3L,TBC1D17,CDCA4,MSL1,MAP2,WIPI1,P4HA2,DOLPP1,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,POMT1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DHRS3,PGAP1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,GATA2,CMTR2,PAK2,EXOC8,MDFIC,TMEM8A,ALDH3A2,PSMA5,ABCC1,C9orf9,CYP26B1,CHSY3,MRPS33,PCBP3,CORO2A,SPATA13,KBTBD8,TCF7,IFIT3,ZDHHC3,G2E3,SMN1,MAPKAPK2,EPN3,MOSPD3,COQ10A,H1F0,PVRL2,CSF1,MFSD2A,PRPS2,LTBP2,ATP1B3,TMEM120A,CTBP1,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,ERBB2,CCNL1,FAM198B,LPIN3,CYP26A1,C1orf116,SDF4,PER2,CDK14,RAD23A,ATP6V0B,SRPX,EFR3A,LHX6,PLCG2,N4BP3,MINPP1,EGLN3,FAR1,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,TIMP2,MBP,EVA1A,TCEB2,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,MYPOP,DNAJC10,RTN4RL1,ATP1A1,PSMD3,ANXA9,ZBTB6,RPL22,AIFM3,LTA4H,CNEP1R1,ZNF701,POMGNT2,NDST3,COPG1,ZC3HC1,MAN2B2,GSDMD,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,CD63,ADGRG1,RUSC2,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,SIRPA,GBX2,CCDC92,CEP97,MAGEE1,SLC35B4,BUB1,ABCD1,KLF9,HEXIM2,CAMK2G,TLE6,FAH,MLEC,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,CAPNS1,CARD19,TRIM35,FXR2,AKAP3,FNDC3A,BCAR1,MAPK8IP1,SCRN2,PRDX4,FUCA1,TMEM50B,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,TMC5,NMI,PGRMC1,PPP2R3C,PKD2,SPCS3,ACADM,NDFIP1,TBC1D4,UBE2C,SAT2,DIS3L,SUN1,GAA,CFAP74,FAM129B,ATP8A1,KLC2,TAP1,GATA3,PLXNA1,CCNB1,PLA2G16,FAM101B,RIC1,CENPN,NCS1,CHST2,SESN3,CTGF,IQCE,ZFP36,RGS3,STEAP2,AOX1,MTMR11,TFG,PACSIN1,LAMP2,LOC81691,KIFC2,SNTB2,PBK,HSPA12A,CASP9,MGAM,AGO4,TNS1,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SAV1,SLC25A5,TP53I3,ULK2,SGPP1,AHRR,SFXN1,KDSR,HLF,SLC25A4,RBM47,AREG,PLK2,PTER,GNPTAB,TBX1,FAM110C,SARAF,DHTKD1,TMEM8B,TRAF5,RTN3,DLAT,DDX58,KLF2,MRPL44,INPPL1,FRMD4A,HLA-E,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,NOTCH2,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,NECAB3,BDH1,SORL1,CD70,PIKFYVE,CTSD,RIMS2,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,FADS2,DDB2,PMPCB,QSOX1,B3GNT7,MMD,ZNF84,MFI2,B9D2,AMER1,ANO6,PIP4K2C,VEZT,PKM,CYFIP2,KDM3A,GLT8D2,STX3,FRMD4B,FAS,DGKH,SERTAD2,PRKAG2,DCK,NAB2,TCEAL4,FGD6,NR4A2,EFNA1,MAP3K5,NRBP1,IRF1,PLA2G4A,FRMPD3,ELK4,SLC2A4,ARMCX3,CEP70,NLRX1,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,BROX,IRX4,KCTD12,CD274,EGR3,SNN,AIFM2,NUDT12,MNS1,GNB2,SLC25A35,CYHR1,APLP2,ZNF75D,CDKN1B,TNPO2,DAB2IP,LGMN,NR2C1,TMBIM1,GPX4,MYO5B,SEC23A,CDKN2AIP,TMEM43,CAPN6,DMTN,LYRM1,TEP1,COX11,SLC11A2,PRKCQ,AKR1E2,H2AFV,SP4,ZNF469,NIN,PRDM11,EPHA10,ZNF641,FYN,JAK1,PPP2R5A,ACYP1,CFAP45,STK26,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,HS3ST3B1,B4GALT3,NR3C2,ATMIN,MRPS9,WASF3,NUDT6,PCOLCE,ANKRD13D,JRKL,ATP9A,ARL4C,CCNJL,GPR180,APOBEC3H,SEPP1,SPR,SLC35G2,LGALS3BP,TEAD3,SIX4,RND1,AKIRIN1,SNTA1,FAM111A,OXCT1,PHF7,PTEN,PPP1R10,MGAT1,CENPJ,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,TAGLN2,CNOT6L,MAP3K7,GFI1,CNPY3,SPRY2,NCOA2,SMC4,PCCB,SHMT1,CASK,ERMAP,DENND1B,MPP1,TEF,PARP4,FURIN,VAMP3,C1GALT1C1,GPLD1,NUCB1,RGS9,CTNS,PRDX3,SLC25A40,SERPINB5,CSTF2,GPER1,ARSB,NCAPG2,SLC25A38,CPEB2,OCLN,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,ST13,CPT2,CAMKK1,HEBP1,UBE2Z,KIF2C,TAF6L,DNER,TMC1,TSEN34,SH3KBP1,ABCD4,CHPF,MAGOHB,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,ANKRD12,KIF22,SUN3,RAB20,RP2,NFU1,MYH14,ARNT2,TECR,PTPRE,RASGRP1,ATL1,TDP1,SOD1,TRIM8,ASCL5,SYNE3,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,TCN2,SEC14L2,CXXC4,NEIL1,ZNF114,FASTKD1,UEVLD,TRIM45,IARS2,APBA2,RAP1GAP,PSMC1,PPP2R5D,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,ELOVL7,ASL,ATP6V1E2,SAMD9,PHLPP1,ZNF432,CA2,EBF4,ZNF692,KNTC1,RFX5,ACAD8,NCEH1,LRIF1,HP1BP3,KDELR1,OXR1,GYLTL1B,HMG20B,FBXO8,EGFR,MUM1L1,GLCE,GNAS,FECH,NUDT16,TSC1,ONECUT1,PLPP3,UTP14C,PAPD5,NFKBIA,CDCA5,ALPK3,PITPNA,KIF12,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,SLC2A8,PSME2,MORC4,TDRKH,ZMYND10,PATL2,MICALL2,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,SMO,GOT1,STEAP3,TWIST1,RPN2,F2R,LOXL1,PDIA6,SCYL3,HSPA2,GCA,ZNF525,TAF5,BAG4,KREMEN2,SLC39A8,OSTM1,AP5M1,IGSF8,ERBB2IP,SNAPC2,DUSP4,BFSP1,BHLHB9,PEX2,CANT1,OVOL1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,CDS2,SORT1,JKAMP,POC1B,FRMD6,MIER3,AES,TRMT2B,POMGNT1,SAC3D1,ZNF212,IRF2BPL,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,CKS1B,BRD7,TRIM3,HSPA13,MXD3,SUN2,SYPL1,ADAM17,RAB3B,CENPC,ASPM,NR4A1,MBNL3,OGDHL,POLD3,MPV17L2,SPAG1,MAP1B,KLHL2,HLA-B,GAREM2,MARC1,C2orf70,DHRS2,PRCP,HNRNPH2,UBE2D2,TADA2B,OTUB2,GLB1,HOXB13,GEM,ATP6V1C1,SOX8,LRRC57,ZNF596,SNPH |
| 2.291e-19 | -42.92 | NUYTTEN_EZH2_TARGETS_DN | MSigDB lists | NUYTTEN_EZH2_TARGETS_DN | 957 | 242 | 17758 | 2588 |
FAM171B,ADD1,EPAS1,DNAJC3,NDC80,C1orf198,TGOLN2,KIF2C,CCNB1,PJA2,CENPN,FANCI,LYPD5,MAGOHB,EPCAM,ADPRHL1,PAK6,NPM2,WEE1,C7orf49,ENTPD4,NUP210,UBE2T,METTL7A,TSPAN6,IMPAD1,ARL1,DDHD2,SLC44A1,FUT1,TRPC1,KIF22,HYLS1,NFU1,MARCH2,PACSIN1,MYBL1,IL1RAP,SP5,CYP1B1,LAMP2,PLK1,PCGF5,CENPA,PTPN18,PBK,CASP9,TMEM98,CKAP2L,AURKB,F12,CDK1,VCP,GINS4,PRIM1,KDM4D,RBM47,HPSE,KCNK1,HOXA9,ZNF165,EIF4EBP2,SPRY4,F2RL1,E2F8,HJURP,TBC1D1,ITGA6,MTL5,ASB9,KIF23,RACGAP1,PHLPP1,TNFRSF19,SSX2IP,SH3D21,UBE2Q2,PAIP2B,PAK2,FCHO1,NEK2,MDFIC,KNTC1,SLC12A2,ALDH3A2,KCTD3,GPR161,HP1BP3,EPB41L5,REC8,MRPS33,KIF20A,PQLC3,TBC1D8B,ADCK3,LPGAT1,SPA17,WHSC1,EIF2AK1,KIF20B,ANTXR1,C3orf58,NFIB,DCP2,GLCE,TSC1,SERTAD2,FAM64A,DCK,PHLPP2,CDCA5,PRPS2,RAB31,DCUN1D1,AGBL5,FAM83D,AURKA,MAL2,NDE1,HOOK1,CCNB2,CDAN1,CCNE2,SPC25,DLGAP5,GPR107,FOXM1,PTTG1,TDRKH,RNF182,NUF2,GRK6,TMEM19,STIL,ARHGEF16,SYTL2,CDK14,CCND1,CD46,SS18,CYHR1,RNF220,CCNA2,SP100,KIF14,RTKN2,RNASEH2A,F2R,ZNF365,ETV4,MED30,MAP3K3,PSRC1,FZD4,CDC20,SYNE2,MRPS35,KCTD2,H2AFV,CDC25C,FANCE,AMZ2,BFSP1,PPP2R5A,ACYP1,WWTR1,INPP4B,VSIG10,C1orf43,REEP4,GEN1,ISOC1,CBX7,ATMIN,CMTM4,MAN2B2,GLIS3,CMAS,PACSIN2,GOLIM4,TRAPPC10,MPZL1,DEPDC1,SLC16A14,CENPI,CCM2,CDCA3,SWI5,CDCA8,ERCC6L,OSGIN2,FLOT1,SLC25A43,IFT27,LBR,SIRPA,VPS26A,FZD6,SAC3D1,GBX2,SGPL1,TOP2A,C16orf59,CEP97,ADD3,CENPJ,ALG13,PRC1,ZDHHC13,CKS1B,BUB1,IQGAP3,SLC45A3,SMC4,HMMR,SYPL1,HES1,SHMT1,ZWINT,PSMB4,HMGN5,ASPM,MRS2,SYBU,C2orf69,AIF1L,BORA,C4orf27,SPAG1,KLHL2,DDAH1,ACADSB,NEIL3,CSGALNACT1,CENPE,ATP6V1C1,NUP37,CEP41,UBE2C,PTGES,DIS3L,PHC1 |
| 2.444e-19 | -42.86 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | 430 | 135 | 17758 | 2588 |
KLK10,MMADHC,IL18,FAM101B,SH3KBP1,PLS3,BTG3,OSBPL3,ALDH1A3,AKR1B1,PIK3CD,IL1RAP,ERAP2,TUBA4A,ASXL1,LOXL2,PPP1R14C,BMP1,PRKCDBP,F2RL1,ARAP3,SERPINE2,TBC1D1,HLA-E,ITGA6,UBASH3B,PM20D2,SAMD9,SLC1A3,GPSM2,S100A2,RAC2,ITGA3,AIM1,PPP4R1,FXYD5,MDFIC,ALDH3A2,CCDC88A,SNX7,HP1BP3,FAM69A,ELK3,KLK5,STAT4,BTN3A2,IFIT3,ANTXR1,EGFR,FAS,STK17A,ETS2,TMEM30A,FAM83D,OSMR,MDH1,ATP1B3,ARPC2,TMEM173,PLA2G4A,FAM92A1,TRIP10,IL15,RALBP1,RGS20,DGKA,PKP2,PHLDA1,SP100,SRPX,RALB,TAX1BP3,CDH3,GM2A,SOAT1,MBP,AGPS,DOCK5,MYL12A,ATP10D,CASP4,IRS2,PTGS2,DUOX1,ATP1A1,CORO1C,AXL,SLC9A6,PTK7,WWTR1,KLF5,BIN1,FBLIM1,ANXA3,MPZL1,IGFBP6,SH3D19,FRMD6,GNAL,DSE,GSTP1,ETS1,NFAT5,SRPX2,ICAM1,FZD6,SIRPA,CD109,ADD3,ITGB8,CTSC,CALD1,TOX2,SGK1,CCDC82,ITM2C,SPRY2,WBP5,PDGFC,PLSCR1,NR3C1,PARP4,VAMP3,EMP3,RUNX3,YES1,RND3,TWSG1,NMI,CLIP4,SERPINB5,FHL1,CYBRD1,DCBLD1,ESYT2 |
| 2.680e-19 | -42.76 | ovary-other-neoplasm | COSMIC cancer mutations | ovary-other-neoplasm | 13367 | 2120 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,SPSB1,SLC35E4,GRM5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,UXT,TFAP2C,PNKD,ABR,LCP1,PIAS3,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,TMEM173,DMPK,WDR63,MGST2,KIAA1147,RBM23,MUC16,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,B4GALNT1,TNS3,RINL,FRAS1,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,CDK5R1,PRX,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,TMX4,RHPN2,PCBP1,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,C1orf198,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,BHLHE41,AIM1,MSH2,PRKG1,ADCK2,OSTF1,CACNA1D,GPR161,TRAK2,GFPT1,GCC2,PRODH,KLK5,CEP89,DCHS1,PYGL,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,KLK7,PER3,EHD1,FOXO6,TCF25,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,OSBPL7,MED30,NAGA,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,ZNF704,CBX7,MAMDC2,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,EFNB1,FGF19,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,CYP1B1,CENPA,ASXL1,ITCH,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,LASP1,ARAP3,PPP1R2,ZNF395,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,TGFBR1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,RC3H2,TTC7A,LEMD2,ENDOD1,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,NRG2,LYNX1,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,ODF2L,NWD1,TNIP1,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,PDPR,ALDH6A1,FAM169A,TMTC3,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,DRP2,NDE1,ZNF502,TRPC3,EGLN1,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,STX10,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,PARP14,MAN1A2,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ZNF230,AK3,ITM2C,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ANLN,FAM212B,CLCN2,RHEB,PLEKHB1,VCP,DPYSL3,MFAP3L,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,CORO2A,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,RAD23A,CDK14,ATP6V0B,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,RPL22,AIFM3,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,RUSC2,DAP,GNE,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,IGDCC4,MLEC,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,NDFIP1,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,SLC20A1,SESN3,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,DLAT,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,TMPRSS4,GNB2,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,ANKRD13D,PCOLCE,SLC16A14,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,SGK3,PRC1,ATP8B1,ERCC2,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,VAMP3,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,OCLN,HEBP1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,IMPAD1,PHTF1,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,IARS2,TRIM45,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KHNYN,ZDHHC12,FRYL,SMO,RPN2,GOT1,APIP,LOXL1,F2R,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,BFSP1,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,FAM219A,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,IBTK,AK7,GRIK2,SLC25A13,RET,TRAPPC8,LACTB2,BAIAP3,SNX9,LTBP3,CARD10,CMTM6,CDKN2C,NAPG,MUC4,TMEM37,WBP4,TIPARP,TIAM1,MGAT5,DSTN,TMEM98,CDA,TMEM151A,PRKAR2B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,ATP5H,RIMS3,MEGF8,RANBP1,FBXO7,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,HPS3,PQLC3,SHARPIN,KIF20B,GNA11,PSMA4,SFXN5,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,NQO1,LFNG,APOO,RHBDL3,FAM91A1,REPS1,MOCS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,MX1,TMCC2,COL6A2,SEC61B,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,TRAF2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,PDCD10,ITGB8,TMEM62,KNDC1,FAM20B,PARP9,ADAMTS2,PLSCR1,UBE2A,CXorf57,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,PPM1H,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,LMCD1,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,CTNNB1,TM9SF2,NPNT,IL6ST,MITF,SLC44A1,PAPSS1,PSMC2,THRB,KRT80,PLK1,KCNIP3,CELSR2,CKAP2L,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,ADCK5,SORBS3,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,RGMB,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FA2H,P4HA3,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,ST3GAL1,FAM134B,BIN1,CMAS,CPEB4,SCD5,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,FZD6,SH2D4A,NRP2,IL22RA1,VPS26A,PARM1,M6PR,C16orf74,CD109,ALPP,FAM63A,GTF2F2,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,GOLGB1,ARHGEF4,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,ZNF823,STIM1,PIK3CA,POLL,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,PRKAA1,APBA1,TNFRSF19,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,APOBEC3B,CD46,C11orf84,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,FAM195A,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,CKAP5,FJX1,FUT8,ERBB3,MSH6,ZWINT,LONRF3,PAPD7,TCFL5,TMEM221,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,MAP1LC3B,ECI1,ADPRHL1,SIPA1L2,SIVA1,STK35,LAMP3,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,FAM81A,QSOX2,TYW3,FAM20C,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,SHROOM2,JAK3,COL16A1,DRD1,LMO7,CCNE2,HDAC11,OSR2,EXT2,MXD1,KCTD9,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,TOP2A,MZT2A,ADRBK1,TAF1B,LLGL2,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TINAGL1,PIK3CD,ACOX2,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,CYP2J2,MERTK,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,SPTLC2,RHOB,PTPRF,SCARB2,OSMR,DYSF,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,ZNF385B,UHRF1BP1L,DACT1,SSH3,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,WWP1,MAPK11,NKAPP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,UPF3B,FOXM1,XYLT1,ZNF28,CCNL1,LPIN3,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,SAT2,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,ITGA3,CYR61,PIK3AP1,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,PTPRH,KCTD20,VEZT,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,ISM1,DCK,FGD6,NR4A2,MAP3K5,CEP70,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CAPN6,TMEM43,LYRM1,COX11,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,ATP9A,CCNJL,SEPP1,SPR,SIX4,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,CASP3,LTBP1,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,ARHGEF10L,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,FOPNL,RNF165,PTGFRN,STK17B,LRRC42,NEIL1,FASTKD1,DHRS13,ADIPOR1,APBA2,MIIP,PSMC1,ELOVL7,SAMD9,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,KNTC1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,EGFL7,PITPNA,KLF7,FBXW5,ZSWIM5,IL15,SLC2A8,GMPR,PATL2,MICALL2,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,POLD3,MAP1B,KLHL2,TADA2B,UBE2D2,HOXB13,GEM |
| 1.357e-18 | -41.14 | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MSigDB lists | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 1033 | 254 | 17758 | 2588 |
EMX1,SIGIRR,EPAS1,PPM1J,SLC25A13,RET,TAP1,FHDC1,CACNA2D2,CCNO,NDRG2,F11R,TP53I11,MGAT5B,SDC1,CARD10,DAPK2,CPNE2,AP1M2,CTGF,NPNT,ZFP36,PAQR5,PAPL,KCNS3,SERINC2,DUSP10,RAB20,TACSTD2,NTN4,TMEM37,SCARA3,SP5,SMAGP,PTPN18,USP18,TMEM98,EZR,KDELR3,ROR1,PIF1,ANLN,ZBTB7B,LHFPL2,STK17B,CDK1,ARHGEF26,COL12A1,IRX3,PGF,TRIM47,ENPP1,CARHSP1,GRID2IP,AGPAT2,AREG,ATP7B,FAM110C,RAB11FIP1,SPRY4,LEMD1,UNC5B,ITPKA,F2RL1,MAFF,E2F8,GAB1,TC2N,KLF2,SCN5A,SERPINE2,CDKN1C,HJURP,LGALS3,BVES,SOX9,KIF23,SLC1A3,DHRS3,ANO1,PRRG4,MECOM,BMP2,TNS3,PIK3AP1,CYR61,GATA2,ICAM5,ZIC5,EBF4,TMEM51,PRKG1,MDFIC,C10orf54,MOXD1,NTN1,GAD1,ALS2CL,SNED1,SNX7,DPYSL5,PRODH,PRSS23,MYBL2,PDE5A,NFIB,EGFR,FRMD4B,SOX13,GNAS,BCAR3,ONECUT1,FAM64A,SLC4A4,PVRL2,ITGA7,MFSD2A,OSMR,DYSF,NXPH4,NR4A2,CDK18,MAL2,CSRP2,PLEKHG3,ARHGAP11A,SLC2A4,CCDC109B,PAX6,SPC25,GRHL2,S100A11,LFNG,ST14,NDRG1,DDIT4L,ERBB2,PKP2,COL18A1,EGR3,SLC7A2,OSR2,STIL,EMP2,CCND1,NOV,RNF220,CDH1,PLCG2,N4BP3,SMO,EGLN3,HSPA2,SULF2,MYO5B,SNX8,KREMEN2,PTPRU,SLC39A8,PTGER4,UTRN,PRKCQ,ERBB2IP,ATP1B1,DUSP4,ITPR3,DOCK5,MAP3K6,EBF2,FZD7,CMTM7,NFIX,BFSP1,POPDC3,SHROOM3,WWTR1,TSPAN18,KIAA1804,VSIG10,EFNA5,MLKL,HS3ST3B1,SYT13,SGOL1,MAPK12,CTDSP1,GLIS3,NKX3-1,CDH22,CD63,PARP14,TSPAN15,RASSF7,GNAL,BIK,SDC4,NES,NOTUM,FGF19,SIX4,SLC9A2,FZD6,TMEM63A,IL17RB,TOP2A,CXCL16,E2F7,LLGL2,GPC3,BMP7,A4GALT,CD9,ATP8B1,PLEKHF1,IL17RA,BUB1,IGFBP2,TAGLN2,ERBB3,SMC4,GCNT1,NFE2L3,RASGRF1,ADAMTS2,HES1,RAB3B,ASPM,MBNL3,LITAF,PPARA,SNTB1,AIF1L,GRTP1,CRISPLD2,CD83,GALNT3,PROM1,LDLRAP1,SWAP70,FAT4,SMTNL2,PLOD2,FGFR2,RIN3,TBX18,FIBCD1,UACA,LRRK1,ICOSLG,FZD5,UBE2C,SHOX2,OCLN,TLL2 |
| 1.710e-18 | -40.91 | BENPORATH_CYCLING_GENES | MSigDB lists | BENPORATH_CYCLING_GENES | 620 | 173 | 17758 | 2588 |
CASP3,VANGL1,DNAJC3,NDC80,DHX8,KIF2C,MORF4L2,CCNB1,SDC1,BARD1,NCS1,FANCI,ASPHD2,CDKN2C,PCNA,HSF2,UBE2T,CDKL5,RGS3,MITF,PASK,KIF22,PIK3CD,SLC39A10,BTBD3,PLK1,CENPA,ASXL1,PBK,ARHGDIB,PIF1,AURKB,CCNF,ANLN,RHEB,PRIM1,ANKRD10,PLK2,TRIM45,CTNND1,MAPK13,KPNA2,E2F8,PPP1R2,HJURP,SLC25A27,RAB23,KIF23,TXNDC9,GPSM2,LMNA,BMP2,TIMP1,GATA2,NEK2,MSH2,USP1,CTSD,ZMYM1,LRIF1,HP1BP3,HMG20B,KIF20B,RNF113A,SRSF5,ANTXR1,G2E3,NCOA3,INSR,FAM64A,H1F0,KBTBD2,ITPR1,MATN2,FAM83D,AURKA,DONSON,NDE1,PLIN3,CCNB2,AFAP1,RAD21,CCNE2,ARHGAP11A,CEP70,DLGAP5,TUBB4B,FOXM1,PTTG1,NUF2,GRK6,STIL,KIAA1147,KCTD9,PDGFA,CCND1,SS18,CCNA2,LMO4,KIF14,REEP1,TNPO2,CDKN1B,GOT1,IFIT1,CDKN2D,SEPHS1,CKS2,CDKN2AIP,PTPN9,CYB5R2,CDC20,NUSAP1,PKMYT1,DUSP4,ITPR3,KCTD2,CDC25C,FYN,ACYP1,STAT1,ZC3HC1,PRKAR1A,GCLM,CKAP2,DCAF7,CIT,MAN1A2,CDCA3,CDCA8,OSGIN2,GDF15,LBR,DNAJB9,SLC25A36,CKAP5,KIF5B,TOP2A,MDM1,PPP1R10,PRC1,TFAP2A,CKS1B,BRD7,SLC44A2,SGK1,KANK2,BUB1,HSPA13,KLF9,SMC4,HMMR,TGIF1,ZWINT,NR3C1,COL7A1,POLD3,KIF11,BBS2,BORA,DCTN6,NEIL3,CDCA7L,E2F1,CSGALNACT1,UACA,CENPE,WDR62,NUP37,UBE2C,ESPL1,MELK,USP16 |
| 1.745e-18 | -40.89 | cytosol | cellular component | GO:0005829 | 3220 | 636 | 17570 | 2579 |
ACACB,TRIM24,ADD1,TRIM5,AK7,PNPLA2,DNAJC3,XIAP,FBXO2,MMADHC,IL18,KIF26A,TP73,CALM2,CDKN2C,PSMD1,AP1M2,CABP1,ALDH1A3,DNM2,TUBG1,PPP1CA,PIK3CD,TIAM1,APOBEC3G,TUBA4A,NWD1,CDA,PRKAR2B,ARF4,LCP1,ABR,CARHSP1,PLCG1,MID1IP1,CAMK2N2,DNM1L,LIMK1,MYLK,NOD2,HDAC1,SERPINB6,RNASEL,ITPKA,HSPB1,STARD13,GAB1,NFKBIE,SEC61G,LMNA,ATG4A,RAC2,WDFY1,FBXO7,FAM13B,NEK2,MAPK7,NUP85,PHKG2,PPP6R1,MCCC2,UFD1L,HPS3,MAPKAPK3,SHARPIN,NPHP3,ILK,TP53INP2,DPYSL4,PCTP,PSMA4,RHOB,DCP2,PLIN5,FNTA,HTT,AURKA,MDH1,NDE1,ARPC2,TRPC3,RPS6KA3,XDH,EGLN1,DOCK9,DMPK,ARHGAP11A,MTM1,NQO1,PAPSS2,TUBB4B,INPP5D,PTTG1,ETNK1,WDTC1,NUF2,MAPK4,MVB12B,PRKACA,MOCS1,CCND1,SCNN1A,DACT1,TAX1BP3,RASGEF1A,CDKN2D,MX1,SEC61B,PSRC1,RIPK2,LGALS8,PFKFB2,SAT1,CYS1,VPS4B,RAB38,GABARAPL1,IRS2,ALDH3B1,PEX5,CDK19,WWTR1,INPP4B,PDXK,MAPK12,TTC8,GALK1,FARP1,TNRC6C,HSP90B1,TRAF2,HABP4,PKN1,NUCB2,GSTP1,CTNNBIP1,CAPN2,ANK1,PDCD10,ADD3,IRAK1,CALD1,MCF2L,TUBGCP6,BAX,WWP1,MAPK11,S100A6,PARP9,MOB4,AMOTL2,OPLAH,PLSCR1,CTNNAL1,RAPGEF2,PIK3R1,DUSP23,EIF5A2,UBE2A,RAB3IP,BLVRA,SKA1,LDLRAP1,RPL12,ARFGAP3,SSNA1,HMGA1,CENPE,FHL1,CMPK2,NUP37,WDR45B,ACOT7,MYL9,ILDR1,TNK1,EPAS1,CNOT8,CUL4B,ARFGEF1,MCCC1,NDC80,PHOSPHO1,NDRG2,HDAC6,SPTB,INPP5E,RPS6KA2,CTNNB1,SHC3,CNTRL,PAPSS1,PSMC2,DDHD2,NEB,S100A13,PLK1,CD55,KCNIP3,EZR,PRKRA,IDH1,SESN1,CDK1,VCP,RHEB,OPTN,DPYSL3,PLCH1,PI4K2B,TBC1D17,WIPI1,CTNND1,PIK3C2B,KPNA2,MYL12B,RRAGD,PRKAA2,USH1C,BMF,DNAJB2,RASA2,PSMD7,SORBS3,RACGAP1,RAB6A,NCKAP1,DOCK11,CORO1B,VASP,GATA2,PAK2,EXOC8,AHCY,PLCB2,PSMA5,DPYSL5,TESK1,PCBP3,STRADB,IFIT3,UNC45B,SMN1,NMT2,CDK5R1,RASGRP2,MAPKAPK2,DHDH,PHLPP2,NLRC5,CCNB2,RNF146,RAD21,UPF3B,UGP2,DGKA,TP53,RHPN2,STIL,BCAP31,CDK14,WDR44,PLCG2,PLK4,GYS1,NOTCH3,TMEM64,OAS3,EGLN3,DVL2,CTH,TCEB2,AKT1,CDC20,ACO1,MYL12A,IDE,PAFAH1B3,PSMD3,CHMP4B,IRF7,ANXA9,RPL22,ARHGAP4,LTA4H,COPG1,CMAS,PINK1,PACSIN2,TRAPPC10,TAB3,RUSC2,HAL,BLVRB,GNE,CDCA8,ERCC6L,PSMD10,CRABP2,AIP,VPS26A,CEP97,TFAP2A,SGK1,TRIM21,BUB1,ALDH7A1,ABCD1,CPLX1,SYK,CAMK2G,FAH,RHOA,PSMB4,PRICKLE1,DPP9,CAPNS1,GGH,CARD19,FXR2,PELI3,FNDC3A,BCAR1,BBS2,BORA,MAPK8IP1,BCL10,PRDX4,CNOT2,DDAH1,NAT1,NIPSNAP3A,PKD2,UBE2C,ARHGEF9,ARHGEF4,TXN,TSC22D3,FAM129B,KLC2,CUL1,PSME1,NANS,CCNB1,PLA2G16,RIC1,CENPN,NCS1,TYMP,CTGF,ELMO2,ZFP36,RGS3,OSBPL3,PALD1,STEAP2,AOX1,PIK3CA,IRF2,TACSTD2,PACSIN1,TFG,METAP2,CASP9,AGO4,AURKB,SAV1,POR,ULK2,DHTKD1,MAPK13,F2RL1,TRAF5,FGD1,DDX58,INPPL1,SCOC,DHPS,TBC1D1,CALB2,DGKQ,PRKAA1,KIF23,ISYNA1,APBA1,HERC6,PSIP1,MECOM,CALR,PIK3AP1,RPL39,CTPS1,PRKG1,PIKFYVE,EEF1D,GFPT1,B9D2,CEP89,CALM1,AMER1,PYGL,CYFIP2,PKM,RASA1,PDE11A,FAS,NT5C2,PRKAG2,PELI2,DCK,ARAP1,AGBL5,MAP3K5,IFIH1,IRF1,PLA2G4A,KIF3C,SLC2A4,CEP70,TRIP10,THRA,RPS6KA1,NDRG1,IQGAP1,CAST,RALBP1,FTH1,BCL2L1,AIFM2,EPM2A,CDKN1B,DAB2IP,EPHB4,IFIT1,PDE4D,PHKA2,OSBPL7,SULT2B1,GPX4,ATG4D,DOCK4,SEC23A,COG2,DMTN,PANK1,PRKCQ,PKMYT1,ITPR3,CBL,CEP162,FYN,JAK1,STK26,NGFRAP1,STAT1,PPP1CB,MLKL,AREL1,PRKAR1A,OTUD5,ARHGEF3,CENPI,CDCA3,HERC5,SPDL1,SPR,CKAP5,RND1,PTEN,CENPJ,PRC1,SGK3,MAP3K7,CNOT6L,TTPA,TRIM62,SPRY2,SMC4,FARP2,RASGRF1,PCCB,SHMT1,CASK,ARHGEF28,ZWINT,ARAP2,DENND1B,VAMP3,DIAPH2,YES1,FOS,KIF11,CPTP,DCTN6,PRDX3,PGM2L1,ERAP1,GPER1,ESPL1,OCLN,CASP3,ST13,CAMKK1,UBE2Q1,VARS2,KIF2C,CACNB4,SLC8B1,MAP1LC3B,TRIM68,SH3KBP1,CHPF,DPYSL2,CEP78,DLG1,AKR1B1,TRPC1,KIF22,MYH14,NFU1,BTBD3,RASGRP1,FGFR1OP2,NLRP4,SOD1,CENPA,TRIM8,USP18,ITCH,ARHGDIB,EDNRA,SEC14L2,MADD,IARS2,CAB39,SP6,RAP1GAP,PPP2R5D,PSMC1,CAPN1,FAM213B,ARAP3,PPP1R12A,SERPINE2,PEX6,ASL,ATP6V1E2,CALM3,TEC,PHLPP1,NOXA1,CA2,PFKL,OCRL,PRKCI,SRP54,NPTN,KNTC1,CCDC88A,PDE5A,NUBP1,RANBP9,AMDHD1,RHPN1,GNAS,TSC1,UAP1,NFKBIA,CDCA5,RHOBTB2,JAK3,DRD1,CCNE2,LZTFL1,SORBS1,SPC25,PSME2,GMPR,MICALL2,ARHGEF16,KIF14,FABP6,DIXDC1,GOT1,NFKB2,F2R,HSPA2,UPF3A,CHP1,MAP3K3,BAG4,RFK,OSTM1,AP5M1,GLO1,CDC25C,CASP4,SOCS3,ARHGAP35,JADE1,STAT6,TLE1,SPTBN5,SGOL1,GCLM,FBLIM1,ENO2,ARHGEF11,ARHGEF7,CIT,SH3D19,SERPINB9,SYDE2,CARD8,ADRBK1,ACTA2,IQGAP3,MYO5A,PGM1,RAB3B,CENPC,GCLC,OGDHL,MAP1B,ARHGAP24,KLHL2,SWAP70,CASP7,RAP2C,DTX4,UBE2D2,ARRB1,ATP6V1C1,CEP41,AHR,NGEF |
| 1.964e-18 | -40.77 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | 458 | 139 | 17758 | 2588 |
TRIM2,TSC22D3,PPFIBP2,LMCD1,GATA3,LYNX1,DNER,ERP29,DENND2D,PLS3,EPCAM,RAB15,ALDH1A3,CLDN4,TACSTD2,MANF,TINAGL1,TMEM37,TIPARP,SP5,SMAGP,CYP1B1,LAMP2,SERTAD4,EZR,TFAP2C,ERP44,EAF2,ARHGEF26,KCNMB4,GPRC5B,KCNK1,FAM110C,SP6,MAPK13,WBSCR27,SLC31A2,ALDH6A1,FXYD3,SOX9,B4GALT4,DHRS3,ANO1,ELF3,RALGPS2,FAM189A1,KCNN4,BDH1,AIM1,TMEM51,SLC12A2,MDFI,CORO2A,CALCRL,MFSD2A,NFKBIA,TMEM159,PROM2,ADAMTS16,PLA2G4A,NQO1,DDIT4L,ATP2C2,C5orf30,BCL2L1,EMP2,KBTBD11,ARHGEF16,CYP26A1,C1orf116,PDGFA,SCNN1A,CDH1,LMO4,ENPP5,CDH3,BRI3,GLB1L2,ACSL4,DLG3,TSPAN1,ETV4,HSPA2,SEMA3B,SUSD3,MYO5B,ERMP1,MBP,SLC39A8,CYS1,ASB13,ATP1A1,ABHD12,SIPA1L1,KIAA1804,TLE1,FAM149A,ANXA9,HS3ST3B1,SLC25A30,ST3GAL1,PRR15,ANXA3,COL9A3,NKX3-1,IGFBP6,HMGN3,COL4A5,HLA-A,XPR1,SLC9A2,M6PR,HDAC9,SNTA1,RNF128,LLGL2,LYPD6,SGK1,TSPAN13,IGFBP2,KLF9,CITED2,FAM134C,TLE6,PDGFC,PLSCR1,GCLC,RAB3IP,AIF1L,CRISPLD2,GPLD1,ENDOD1,HLA-B,FGFR2,FAM3C,HOXB13,LRRK1,PTGES,FOXA1 |
| 2.482e-18 | -40.54 | regulation of catalytic activity | biological process | GO:0050790 | 2284 | 484 | 16441 | 2455 |
TXN,PPP4R4,IBTK,DNAJC3,RET,XIAP,CUL1,NRG2,PSME1,CCNB1,SNX9,CARD10,RIC1,ELMOD2,GRM5,TP73,NPM2,CALM2,CDKN2C,PAK6,PSMD1,ARHGAP42,RGS12,CTGF,CABP1,RGS3,PPP1R16A,SERINC2,PIK3CA,DNM2,CRY2,RCAN3,TIAM1,NEK4,ACVR1C,CASP9,PRKAR2B,PIF1,AURKB,PPP1R14C,POR,ARF4,ARHGEF26,ABR,PLCG1,MID1IP1,CAMK2N2,SH2D3C,LIMK1,PPP2R4,NOD2,MAP3K11,AGFG2,SERPINB6,SERPINI1,HSPB1,STARD13,GAB1,FGD1,CDKN1C,TBC1D1,NUAK1,ITGA6,PRKAA1,GPSM2,BMP2K,SH3RF2,TFAP4,RAC2,RALGPS2,CYR61,SNX18,FBXO7,PPP4R1,FAM13B,RANBP1,NEK2,MSH2,DAPK1,MAP3K9,PRKG1,SORL1,NCAM1,MAPK7,PPP6R1,TMED2,GPR161,SOCS5,MMD,TBC1D8B,MAPKAPK3,CALM1,EPHA1,ILK,CYFIP2,PSMA4,PLIN5,RASA1,FAS,MMP15,FNTA,PRKAG2,HTT,SEMA4D,ITPR1,ARAP1,FGD6,NR4A2,STK39,CABIN1,EFNA1,MAP3K5,SERPINB1,RPS6KA3,XDH,EGLN1,DOCK9,DMPK,PLEKHG3,ARHGAP11A,SPRED1,GRHL2,NQO1,RPS6KA1,RALBP1,CAST,IQGAP1,PTTG1,WDTC1,RGS20,MGST2,PRKACA,FLT3,EPS8L2,CCND1,CD46,APLP2,ST5,CCNA2,ACAP2,SH3BP1,RALB,FICD,CDKN1B,TAX1BP3,DAB2IP,IFIT1,DLG3,RASGEF1A,CDKN2D,TMBIM1,TBC1D10B,DOCK4,CAMSAP3,PSRC1,RIPK2,NRBF2,FZD4,PFKFB2,COX11,PRKCQ,SLC11A2,ATP1B1,PKMYT1,ITPR3,IRS2,FYN,JAK1,CCNB3,PPP2R5A,NGFRAP1,STK26,WFS1,CORO1C,WWTR1,SIPA1L1,PLEKHG1,KIAA1804,SLC27A1,NRG1,RGS14,DENND5B,MAPK12,PRKAR1A,ARHGEF3,FARP1,PCOLCE,TAOK2,NKX3-1,HSP90B1,DEPDC1,TRAF2,SDC4,NES,HERC5,PKN1,SPR,GSTP1,ARHGEF40,TIPRL,FGF19,ICAM1,DIRAS3,PDCD10,IRAK1,CTSC,PTEN,PPP1R10,KNDC1,GPC3,MCF2L,CST3,BAX,TMBIM6,MAPK11,ERBB3,MAP3K7,RAG1,GFI1,SPRY2,MSH6,FARP2,RASGRF1,PDGFC,ARAP2,ARHGEF28,PLSCR1,DENND1B,RAPGEF2,PIK3R1,GRIN1,FURIN,RAB3IP,GRTP1,TXK,GPLD1,CDK5RAP1,RGS9,TIMP3,KIAA0141,FGFR2,PRDX3,RCBTB2,RIN3,ARFGAP3,SERPINB5,GRIN2D,GPER1,CENPE,FZD5,CD81,CPEB2,CCNC,CASP3,FAF2,AGRN,CAMKK1,EPHA4,ARFGEF1,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,ERP29,DENND2D,SPTB,ARHGEF10L,SIPA1L2,PCNA,CTNNB1,RABEP2,NPNT,SHC3,CDKL5,ARHGEF37,ARL1,PSMC2,DLG1,DUSP10,RGS5,RP2,SLC39A10,RASGRP1,PLK1,SOD1,ARHGDIB,PRKRA,CDK1,VCP,EDNRA,SEC14L2,PLEKHG6,NEIL1,TBC1D17,ARHGEF19,GPRC5B,MADD,CAB39,GLA,RAP1GAP,PSMC1,PPP2R5D,PIFO,ARAP3,LMTK3,PPP1R2,SERPINE2,PPP1R12A,BVES,RASA2,UBASH3B,FXYD3,PSMD7,CALM3,RACGAP1,DOCK11,FBLN1,DUSP5,BMP2,RB1,TIMP1,NOXA1,IGF1R,RINL,OCRL,PAK2,TBCD,FNIP1,MDFIC,PIM1,WNT3A,PLCB2,ALS2CL,CCDC88A,PSMA5,MDFI,SPATA13,STRADB,PDE5A,FBXO8,SCRIB,BCL2L13,EGFR,CDK5R1,RHPN1,RASGRP2,GNAS,MAPKAPK2,BCAR3,TSC1,INSR,CSF1,SH3BP4,DCUN1D1,NLRC5,CTSA,ATP1B3,JAK3,IFI6,DRD1,PROM2,CCNE2,AVPI1,NF2,PSME2,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,EMP2,STIL,BCAP31,ARHGEF16,SYTL2,PDGFA,KIF14,PPME1,BCL6,CDH3,TMEM64,OAS3,EGLN3,F2R,HSPA2,GM2A,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,PPIF,TIMP2,BAG4,RFK,AKT1,CDC20,DUSP4,CD40,CDC25C,DOCK5,MAP3K6,ARHGAP35,SOCS3,DNAJC10,PTPRJ,RBL1,MMP17,PSMD3,STK38,EFNA5,SPTBN5,RCAN2,ARHGAP4,PPP2R2D,ARFGEF3,ANXA3,GCLM,PINK1,SORT1,TAB3,ARHGEF11,DAP,ARHGEF7,CTSB,SERPINB9,GNAL,PSMD10,TGFBR1,TRIB2,SBF1,AIP,PARM1,PPP2R3A,SH2D4A,ZDHHC21,SYDE2,CD109,SNX13,CARD8,ADORA1,ADRBK1,LLGL2,BMP7,SGK1,CKS1B,H2AFY,BUB1,HEXIM2,IQGAP3,SYK,RPGR,CAMK2G,DUSP1,ADAM17,RHOA,PSMB4,PLAUR,RGCC,STMN3,COL7A1,LEPR,MAPK8IP1,BCL10,ARHGAP24,DDAH1,CASP7,SERPINA1,SPINT2,FGF18,RAP2C,ARRB1,PPP2R3C,PKD2,TBC1D4,UBE2C,HIPK3,ARHGEF9,PKIA,RAB3IL1,ARHGEF4,NGEF |
| 3.026e-18 | -40.34 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | 423 | 131 | 17758 | 2588 |
EXPH5,SIGIRR,TSC22D3,PPFIBP2,GATA3,F11R,ERP29,FAM46C,DENND2D,EPCAM,AP1M2,RABEP2,GRHL1,METTL7A,IQCE,PPP1R16A,FUT1,SERINC2,CLDN4,MYH14,KIFC2,USP18,ZBTB7B,PLCH1,RBM47,DHRS13,ZNF165,ARRDC1,TTC9,EPB41L4A,TC2N,CCDC97,PRSS8,LMTK3,ALDH6A1,FXYD3,CCDC64B,ANO1,PDXDC1,PRRG4,ELF3,MYO5C,AIM1L,LYPD3,SORL1,CADPS2,CACNA1D,MYLIP,MCCC2,EPB41L5,PRODH,PLEKHA6,PCDH1,SLC37A1,PIP4K2C,EPHA1,SPTLC2,GOLT1A,CYB5A,RHOB,RHPN1,SOX13,EPN3,FA2H,TJP3,FAAH,MAL2,HOOK1,TOB1,RUSC1,PROM2,GRHL2,ST14,ATP2C2,ERBB2,EMP2,DDR1,CDS1,PER2,CYHR1,CDH1,ENPP5,CDH3,CNNM4,DLG3,TSPAN1,RAB27B,SULT2B1,SCYL3,MYO5B,SSH3,CAMSAP3,KIAA0040,PPP2R5A,WFS1,FAM195A,OVOL1,ANXA9,C1orf43,PRR15,MACC1,SLC16A14,ESRP1,BIK,BLVRB,CYB561,CRABP2,SEPP1,MLPH,LLGL2,MGAT4A,MCF2L,FAM63A,TRIM3,FAM102A,TMBIM6,SLC44A2,TSPAN13,IGFBP2,ERBB3,SLC35A1,PVRL4,CRIP2,NPDC1,SYT7,CCDC6,SPINT2,TADA2B,PPM1H,FOXA1,ABCG1 |
| 3.150e-18 | -40.30 | anatomical structure morphogenesis | biological process | GO:0009653 | 2356 | 496 | 16441 | 2455 |
GAA,CFAP74,ACVR1,ADD1,HSPG2,LGR4,SSH1,AK7,RET,CCNO,GATA3,CUL1,NRG2,IL18,PSME1,PLXNA1,VASH1,FAM101B,CALM2,TP73,WEE1,TYMP,PSMD1,TGFBR3,CTGF,STIM1,ALDH1A3,PIK3CA,DNM2,TACSTD2,PPP1CA,PACSIN1,RCAN3,TIPARP,TIAM1,CPE,DNAAF3,SPEF2,CASP9,TFAP2C,LOXL2,SAV1,ZFAND5,ULK2,ARHGEF26,COL12A1,ABR,LCP1,PGF,PLCG1,AREG,DNM1L,LIMK1,TBX1,TRAF3IP1,NKD1,MYLK,LRIG1,BMP1,HDAC1,TMOD2,UNC5B,E2F8,HOXC13,FGD1,SCN5A,KLF2,INPPL1,CDKN1C,TMTC3,ITGA6,SOX9,RAB23,SLC1A3,NOTCH2,MERTK,ELF3,MECOM,RAC2,ITGA3,FRY,CYR61,FLRT3,MEGF8,BHLHE41,TNFRSF12A,MYDGF,CACNA1D,NCAM1,PIKFYVE,TTLL1,TMED2,DNAI1,EPB41L5,B9D2,SALL4,CEP89,CALM1,DCHS1,FHL2,CALCRL,WHSC1,KIF20B,EPHA1,ILK,NPHP3,ANTXR1,DPYSL4,NFIB,PSMA4,RHOB,RASA1,MMP15,NCOA3,ETS2,SEMA4D,HTT,MATN2,WDR19,NAB2,FAM83D,AURKA,NR4A2,EFNA1,B4GAT1,GDF11,ARPC2,CFAP20,TRPC3,RPS6KA3,ADAMTS16,EGLN1,EHD1,MTM1,SPRED1,FOXO6,GRHL2,TCTN2,ST14,LFNG,THRA,IQGAP1,CAST,RPS6KA1,C5orf30,IRX4,PKP2,BCL2L1,EGR3,PRKACA,DDR1,NOV,DACT1,CNNM4,DAB2IP,EPHB4,DLG3,RASGEF1A,ETV4,SNX10,SEMA3B,COL6A2,FZD4,FOXJ2,SAT1,HTATIP2,SLC11A2,PRKCQ,TANC1,ALCAM,FZD7,NFIX,CEP162,EPHA10,IRS2,FYN,JAK1,SHROOM3,SLC9A6,AXL,WWTR1,PNPLA6,KLF5,NRG1,COBL,ATMIN,PRKAR1A,TTC8,CTHRC1,FARP1,TNRC6C,NKX3-1,SDC4,CCM2,FLOT1,NES,CTSZ,PLPPR4,SPR,ETS1,HOXB2,SRPX2,FGF19,EFNB1,SIX4,RND1,NEO1,SGPL1,SCML1,CTNNBIP1,CAPN2,E2F7,ANK1,PDCD10,PTEN,KNDC1,GPC3,FJX1,BAX,CD9,ADAM15,ATP8B1,ERBB3,ERCC2,MAP3K7,CITED2,GFI1,SPRY2,S100A6,FARP2,RASGRF1,TGIF1,PDGFC,B3GNT2,ARHGEF28,FMN1,RAPGEF2,GRIN1,VAMP3,C1GALT1C1,YES1,RAB3IP,ABLIM2,CRISPLD2,GPLD1,PITX2,CNTNAP1,PROM1,DGCR2,ACVRL1,FGFR2,TBX18,NR4A3,RYK,SERPINB5,ERAP1,GRIN2D,ITGAV,FHL1,FZD5,OSR1,SHOX2,FOXA1,RGMA,MYL9,CASP3,EMX1,UGT8,EPAS1,AGRN,EPHA4,PHOSPHO1,MPP5,SDC1,PDGFB,CACNB4,SPTB,RPS6KA2,CTNNB1,LRRC6,NPNT,SHC3,DPYSL2,IMPAD1,PSMC2,ELF5,DLG1,TRPC1,NTN4,RP2,CTTN,MYH14,BTBD3,RASGRP1,SP5,CYP1B1,THRB,ATL1,SOD1,CELSR2,ASXL1,FOPNL,RNF165,NFE2L1,EZR,ARFRP1,PRKRA,DZIP1L,IRX3,DPYSL3,EDNRA,HS6ST1,HPSE,MAP2,HOXA9,TDRD7,PSMC1,MYL12B,CAPN1,PCSK5,USH1C,RUNX2,SERPINE2,BVES,RASA2,PSMD7,CALM3,NCKAP1,DHRS3,DUSP5,SSX2IP,BMP2,RB1,VASP,CA2,IGF1R,LRRN2,FAM20C,GATA2,FRAS1,OCRL,PAK2,COL6A1,PRKCI,WNT3A,NTN1,SLC12A2,ETV7,PSMA5,MDFI,CYP26B1,DPYSL5,ELK3,RGMB,STRADB,SCRIB,RANBP9,CDK5R1,EGFR,FOXD2,SOX13,BCAR3,GNAS,TSC1,ONECUT1,INSR,PVRL2,COL13A1,ITGA7,CSF1,PLPP3,EGFL7,PITPNA,AKIP1,JAK3,SHROOM2,SEMA3A,RARG,KLF7,PAX6,HOXB7,NF2,FOXM1,PSME2,TP53,P2RX7,COL18A1,ERBB2,RASGRP3,OSR2,ZMYND10,MICALL2,STIL,EXT2,IER3,PDGFA,TTC21B,SS18,SETDB2,ARTN,KIF14,LMO4,FRYL,BCL6,SMO,TWIST1,ECE1,NOTCH3,NFKB2,F2R,DVL2,FRS3,SIRT1,S100A4,DUSP4,MYL12A,DAG1,SOCS3,ARHGAP35,PTGS2,PTPRJ,PTK7,STAT6,PSMD3,PTBP3,TLE1,EFNA5,SPTBN5,PLXND1,LIFR,COL9A3,PACSIN2,ARHGEF11,ADGRG1,POC1B,ARHGEF7,FRMD6,LRP4,PSMD10,AES,COL4A5,TGFBR1,JAG2,CRABP2,ITGA2B,FZD6,NRP2,PPP2R3A,GBX2,CD109,KIF5B,BMP7,TFAP2A,ACTA2,SGK1,RPGR,SYK,MYO5A,CAMK2G,GCNT1,DUSP1,HES1,ADAM17,RHOA,PSMB4,WNT10B,CFAP46,NR4A1,PPARA,PRICKLE1,COL7A1,BBS2,FOXL1,SPAG1,MAP1B,BCL10,CNOT2,LEMD2,ARHGAP24,FAT4,SCG2,TWSG1,PRCP,CTSV,FGF18,SPINT2,CSGALNACT1,PGRMC1,PKD2,HOXB13,PLOD3,CEP41,ZMIZ1,SOX8,L1CAM,NGEF |
| 3.304e-18 | -40.25 | bladder | COSMIC cancer mutations | bladder | 14810 | 2299 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,LCP1,ABR,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,WDR63,DMPK,C5orf30,KIAA1147,MUC16,ENPP5,ZNF365,MYT1,SNX8,C6orf1,RIPK2,APOBEC3D,AGPS,SEPT6,PTPN9,VPS4B,HTATIP2,SYP,DNAJB14,GTF2A2,TANC1,SNX12,ZNF618,TRIM7,NFIX,PDLIM3,CDK19,SHROOM3,WFS1,CORO1C,AXL,SLC25A30,CTHRC1,HSP90B1,CKAP2,BACE1,ESRP1,CCM2,BIK,HABP4,FLOT1,BTN3A1,CTSZ,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,KLC3,BAX,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,PIK3R1,DUSP23,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,INPP5E,BTG3,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,TMEM164,PI4K2B,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,RUNX2,USH1C,PARP12,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,SLC30A6,FCHO1,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,PRX,CDK5R1,COL13A1,OTUD6B,PHLPP2,KBTBD2,NLRC5,PLD1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,PTPRJ,IDE,MAOA,XRCC3,IRF7,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,H1FX,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,ALDH7A1,TSPAN13,CPLX1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,PNISR,SSH1,LGR4,HSPG2,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,SERPINI1,NFKBIZ,SPRY4,F2RL1,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,DOPEY2,BHLHE41,AIM1,PPP4R1,MSH2,ADCK2,PRKG1,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,AGBL5,APPL2,SFMBT1,KLK7,CDK18,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,NAGA,ATG4D,DOCK4,PANK1,UTRN,KIF1C,ATP1B1,PYGO1,PKMYT1,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,GNB5,CD9,CCDC82,CITED2,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,ARSK,KIF11,ACADSB,DGCR2,FGFR2,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,EPCAM,ZFYVE16,HSF2,CASC4,METTL7A,CDKL5,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ADAMTSL4,DUSP5,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,STEAP1,RANBP9,UAP1,SPAG7,RAB31,DCUN1D1,CTSA,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,NCKAP5,SORBS1,PAX6,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ARHGEF7,TGFBR1,NTAN1,SBF1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,RC3H2,SYBU,TTC7A,LEPR,ENDOD1,LEMD2,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,UACA,ARRB1,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,CACNA2D2,SMARCAL1,FAM102B,LYNX1,CNTROB,MORF4L2,SYTL4,BARD1,PHF1,DAPK2,ZYX,AP1M2,TGFBR3,CYP2S1,SLC46A1,KLF3,FUT1,SEMA3G,ODF2L,NWD1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,LSM14B,PDPR,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NAAA,NCOA3,MTFMT,SEMA4D,HTT,SETD3,TEX30,ITPR1,AURKA,ALG2,NDE1,DRP2,FBXO27,TRPC3,ZNF502,EGLN1,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,NUF2,IL13RA1,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,RNF169,SCN3A,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,DTX3L,CAPN2,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,DCAF10,PITX2,CCDC6,ATXN7L3,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,TRIM2,AGRN,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,UBASH3B,ASAH1,DOCK11,PGAP1,BMP2,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,NF2,UGP2,DGKA,ERBB2,RASGRP3,CYP26A1,C1orf116,CDK14,RAD23A,ATP6V0B,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,CHAC2,SIRPA,PPP2R3A,SLC9A2,CEP97,BUB1,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,FXR2,AKAP3,PELI3,FNDC3A,BCAR1,TMEM50B,BANK1,TWSG1,NAT1,ZNF214,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,STEAP2,AOX1,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,PIF1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,NKD1,DHTKD1,TANC2,TRAF5,LZTS1,DLAT,CDK17,MRPL44,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,PKD1L2,IRF1,PLA2G4A,PLEKHG3,FRMPD3,ELK4,S100A11,TRIP10,RPS6KA1,IQGAP1,SUZ12,CAST,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,APLP2,FAM46A,FICD,DOK4,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,ARL4C,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,MGAT1,PRC1,SGK3,ATP8B1,ERCC2,CNOT6L,CNPY3,PCCB,SHMT1,CASK,MPP1,DENND1B,TEF,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,OCLN,NMRK1,CAMKK1,HEBP1,TAF6L,CACNB4,DENND2D,KREMEN1,TMC1,SH3KBP1,ABCD4,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,SUN3,RAB20,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,FECH,GNAS,TSC1,ONECUT1,NFKBIA,CDCA5,RHOBTB2,ALPK3,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SLC25A48,SS18,KCTD15,KHNYN,FRYL,SMO,GOT1,STEAP3,RPN2,APIP,F2R,LOXL1,SCYL3,FRS3,MAP3K3,SUSD3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,JKAMP,FRMD6,ARMC7,FAM134A,TRMT2B,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,LRRC66,MBNL3,OGDHL,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,IBTK,AK7,GRIK2,RET,TRAPPC8,LACTB2,ISOC2,BAIAP3,SNX9,LTBP3,CARD10,ZNF275,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIPARP,TIAM1,TMEM98,CDA,TMEM151A,PRKAR2B,RNF19B,ARF4,PLCG1,BOLA3,ENPP1,ATP7B,CELF5,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,RABGGTA,TFAP4,FLII,PAIP2B,RIMS3,MEGF8,FLRT3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,KANK3,DGKG,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,C11orf45,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,LFNG,CD82,RHBDL3,PTTG1,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,ST5,CDH1,SH3BP1,XYLT2,LRP11,RASGEF1A,DLG3,ETV4,SNX10,MX1,TMCC2,TMEM200B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,UBE2A,CXorf57,AK4,C4orf27,RGPD5,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CCBL2,EAF2,SESN1,KDM4D,TNS4,PLEKHG6,HS6ST1,AGPAT2,KLF12,KPNA2,TC2N,RRAGD,HS6ST3,PRSS8,RMND5A,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,EMP2,STIL,PRR7,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,STK38,MMP17,EFNA5,ARHGAP4,ST3GAL1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,HMGN3,GDF15,LBR,AIP,VPS26A,PARM1,NRP2,FZD6,SH2D4A,CD109,CDK16,ALPP,TFAP2A,FAM63A,SGK1,TRIM21,SYK,WBP5,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,RNPEP,BBS2,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,FAM171B,LAMP1,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,POLL,PIK3CA,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,VASN,RPL39,TPST1,DAPK1,DLX4,KCTD3,ZNF117,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,CAPN12,GPR107,DLGAP5,TCTN2,ST14,THRA,CCDC110,NDRG1,CERCAM,RALBP1,FTH1,BLCAP,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,CBLL1,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,ABCB1,FZD5,WDR91,MELK,UGT8,ERP29,HTR1D,ADPRHL1,RAB15,SIPA1L2,SIVA1,CEP78,CTTN,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,QSOX2,SPP1,TYW3,FAM20C,MTMR10,SRP54,HLA-C,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,CD40,TMTC2,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,SLC35A1,RPGR,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,CEP41,AHR,RAB3IL1,CD33,ABCG1,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,KIF26A,EPDR1,TP73,CALM2,WEE1,RGS12,PQLC2,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,LIMK1,MAP3K11,SERPINB6,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,RAVER2,ELF3,GNS,WDFY1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,OSMR,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,PLEKHG1,INPP4B,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,NEO1,PDIA4,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,WWP1,NKAPP1,MAPK11,NPTXR,SGCB,S100A6,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,NDC80,MCCC1,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,MYBL1,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,EPB41L4A,GLCCI1,BMF,RACGAP1,CNTNAP2,B4GALT4,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CYP26B1,CHSY3,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,MFSD2A,ITGA7,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,SLC7A2,CCNL1,FAM198B,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,SCN2A,MINPP1,DVL2,CTH,CPD,MBP,FIGNL1,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,SELL,GABRG2,JAG2,DSE,GBX2,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,DLGAP1,HMMR,PSMB4,CCDC34,TRIM35,NPDC1,MAPK8IP1,BSDC1,SCRN2,PRDX4,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,SAT2,SUN1,GAA,TTC39B,FAM129B,TAP1,PPFIBP2,GATA3,FAM101B,CENPN,CHST2,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TNFRSF12A,RIMS2,TSPAN33,IGSF3,FADS2,QSOX1,MFI2,TBC1D8B,PTPRH,ANO6,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,LGMN,MYO5B,CDKN2AIP,SEC23A,CAPN6,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,FYN,ZNF641,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,MLKL,HS3ST3B1,ZC3H12B,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,LGALS3BP,SIX4,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,LTBP1,ST13,EPHX4,KIF2C,DNER,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,AKR1B1,POF1B,ANKRD12,RP2,ARNT2,SLC39A10,TECR,RASGRP1,TDP1,ATL1,SOD1,FOPNL,RNF165,PTGFRN,MRPS36,STK17B,SEC14L2,LRRC42,NEIL1,ARHGEF19,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,AIM1L,ZNF432,CA2,LRRN2,FNIP1,ZNF692,KNTC1,RFX5,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,MUM1L1,BCAR3,XKRX,NUDT16,SLC6A6,UTP14C,PAPD5,PITPNA,EGFL7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,PSME2,SLC2A8,MORC4,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,BAG4,TAF5,KREMEN2,SNAPC2,DUSP4,KCTD2,DOCK5,MAP3K6,BHLHB9,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,MXD3,HSPA13,IQGAP3,SYPL1,SUN2,ADAM17,GCLC,NR4A1,DEPDC4,ASPM,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,HNRNPH2,PRCP,UBE2D2,TADA2B,HOXB13,GEM,LRRC57 |
| 3.304e-18 | -40.25 | urinary_tract | COSMIC cancer mutations | urinary_tract | 14810 | 2299 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,KIAA1147,MUC16,ENPP5,ZNF365,MYT1,SNX8,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,SLC25A30,CTHRC1,HSP90B1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,FLOT1,BTN3A1,CTSZ,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,IRF7,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,PNISR,LGR4,SSH1,HSPG2,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,DOPEY2,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,NAGA,ATG4D,DOCK4,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,ARSK,KIF11,ACADSB,DGCR2,FGFR2,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ADAMTSL4,DUSP5,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,UAP1,SPAG7,DCUN1D1,RAB31,CTSA,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,SLC46A1,KLF3,FUT1,SEMA3G,ODF2L,NWD1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,TRIM2,AGRN,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ASAH1,DOCK11,PGAP1,BMP2,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,NF2,UGP2,DGKA,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,NKD1,DHTKD1,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,ZNF84,MMD,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,OCLN,NMRK1,HEBP1,CAMKK1,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,IBTK,GRIK2,AK7,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,RABGGTA,TFAP4,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,KANK3,DGKG,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,C11orf45,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CCBL2,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,KPNA2,TC2N,RRAGD,HS6ST3,PRSS8,RMND5A,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,ST3GAL1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,HMGN3,GDF15,LBR,AIP,VPS26A,PARM1,FZD6,SH2D4A,NRP2,CD109,CDK16,ALPP,FAM63A,TFAP2A,SGK1,TRIM21,SYK,WBP5,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,CAPN12,REPS2,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,ABCB1,WDR91,FZD5,MELK,UGT8,ERP29,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,QSOX2,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,CEP41,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,KIF26A,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,LIMK1,MAP3K11,SERPINB6,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,MYBL1,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,EPB41L4A,GLCCI1,BMF,RACGAP1,CNTNAP2,B4GALT4,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,CTH,CPD,MBP,FIGNL1,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,SELL,GABRG2,JAG2,DSE,GBX2,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,CCDC34,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,FAM101B,CENPN,CHST2,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,CASP3,LTBP1,ST13,EPHX4,KIF2C,DNER,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,RASGRP1,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,ZNF432,AIM1L,CA2,LRRN2,FNIP1,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,PAPD5,EGFL7,PITPNA,FBXW5,GAS2L1,SLC25A24,ZSWIM5,PSME2,SLC2A8,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,HNRNPH2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 4.092e-18 | -40.04 | single-organism cellular process | biological process | GO:0044763 | 11471 | 1890 | 16441 | 2455 |
IBTK,GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,CCNO,TRAPPC8,BAIAP3,SNX9,SPSB1,CARD10,LTBP3,SLC35E4,GRM5,NPM2,CDKN2C,PHYHIP,MUC4,UBE2T,PAQR5,ATP13A3,DNM2,CLDN4,CRY2,PPP1CA,TMEM37,TIAM1,IL10RB,TIPARP,CPE,MGAT5,DNAAF3,NEK4,DSTN,UXT,CDA,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,GINS4,LCP1,ABR,ENPP1,CARHSP1,PLCG1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,HSPB1,STARD13,ANXA11,SCN5A,SEC61G,ITGA6,MTL5,RAB23,GPSM2,COX6C,HPCAL4,TTYH3,ATG4A,TFAP4,FLII,RAC2,ZCCHC17,FRY,MEGF8,ATP5H,RIMS3,FLRT3,FBXO7,RANBP1,PCYOX1,MAP3K9,SLAIN2,CADPS2,USP1,ALPK1,MYDGF,PANX2,CNGA1,MAPK7,ULBP2,DGKG,MYLIP,NUP85,PHKG2,TTLL1,PPP6R1,MCCC2,PAQR7,REC8,PQLC3,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,PSMA4,GNA11,SFXN5,IL1R1,FNTA,SLC4A4,ETS2,DGAT2,CLMN,STK39,GDF11,CFAP20,NUP58,TMEM173,DOCK9,DMPK,NQO1,LFNG,INPP5D,CD82,PTTG1,APOO,C5orf30,MAPK4,GRK6,MGST2,MUC16,CDH1,SH3BP1,XYLT2,ENPP5,TAX1BP3,DLG3,RASGEF1A,MYT1,SNX10,ETV4,MX1,SEC61B,COL6A2,RIPK2,AGPS,PFKFB2,SEPT6,VPS4B,HTATIP2,SYP,XRCC6BP1,TANC1,COX20,EBF2,GIGYF1,GABARAPL1,NFIX,ALDH3B1,PDLIM3,CCNB3,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,MAPK12,CTHRC1,HSP90B1,MPZL1,GCAT,CKAP2,TRAF2,CCM2,BIK,SDC4,HABP4,OSGIN2,FLOT1,BTN3A1,CTSZ,PLPPR4,ZNF219,IFT27,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,DIRAS3,SLC25A45,PDCD10,FUT2,ITGB8,IGSF9,KNDC1,GPC3,MGAT4A,CST3,TUBGCP6,KLC3,BAX,IGFBP2,RAG1,PARP9,ACBD5,PVRL4,OPLAH,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,UBE2A,AK4,RAB3IP,PIM3,CNTNAP1,LDLRAP1,PROM1,RPL12,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,PLA2G15,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,WDR45B,ACOT7,PHC1,TLL2,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,LMCD1,PHOSPHO1,DNAJB11,NDRG2,F11R,TEX2,ITPR2,MGAT5B,SPTB,FANCI,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,CTNNB1,NPNT,P4HB,IL6ST,ARL1,PSMC2,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,MARK1,CELSR2,NFE2L1,CR2,CCBL2,ARFRP1,EAF2,SESN1,DZIP1L,KDM4D,TNS4,TRIM9,HS6ST1,PI4K2B,KCNMB4,AGPAT2,HOXA9,KLF11,KPNA2,TC2N,MYL12B,HS6ST3,RRAGD,RUNX2,USH1C,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,SLC22A31,PDCL,PSMD7,SORBS3,RAB6A,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,TIMP1,FRAS1,KIF13B,TBCD,SLC30A6,SELK,AHCY,PIM1,FAR2,WNT3A,NTN1,DPYSL5,PCDH1,RGMB,MGAT4B,STRADB,SCRIB,PDK3,BCL2L13,PRX,NMT2,CDK5R1,FOXD2,RASGRP2,FA2H,COL13A1,PHLPP2,SLC2A6,ZDHHC7,PLD1,AKIP1,SEMA3A,CCNB2,USP43,RAD21,HOXB7,TMX4,TP53,P2RX7,RHPN2,BAHD1,STIL,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,KMT5C,TACC2,LMO4,PPME1,BCL6,PLK4,ZDHHC23,CDH3,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,PTPRJ,IDE,ABHD12,RBL1,STK38,MAOA,CHMP4B,XRCC3,EFNA5,IRF7,SYT13,ARHGAP4,ST3GAL1,FAM134B,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CPEB4,TAB3,KLHL13,CTSB,SCD5,HAL,GNAL,MCTP2,CDCA8,ERCC6L,GDF15,AIP,IL22RA1,DNAJB9,FZD6,NRP2,M6PR,ZDHHC21,CD109,CDK16,UBE2J1,TFAP2A,SGK1,IL17RA,TRIM21,ALDH7A1,HMGCL,CPLX1,TSPAN13,SYK,FAM134C,ATP2B1,GCNT1,DUSP1,P2RX4,HES1,FBLN5,RHOA,PLAUR,STMN3,MAML2,GGH,COL7A1,TXNDC11,RNPEP,BBS2,DGKE,BCL10,CNOT2,DDAH1,SCG2,NEIL3,FGF18,E2F1,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,SLC35D2,TXN,SSH1,HSPG2,LGR4,TMEM86B,TSC22D3,CUL1,PSME1,PDGFRL,NANS,CAMK1D,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,PAK6,HELZ2,TYMP,CYP1A1,POLL,SERINC2,KCNS3,PIK3CA,IRF2,TACSTD2,ZBTB18,METAP2,SPATA18,ACVR1C,CDYL,BNIP3L,SLC35C1,KIF13A,POR,RAB2B,PRIM1,SH2D3C,PPP2R4,PRDM5,BMP1,MAPK13,F2RL1,SLC31A2,FGD1,SEMA6B,RECQL,MRC2,CDKN1C,DHPS,THEMIS2,TMEM55B,PRKAA1,AKAP17A,TXNDC9,HERC6,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,C9orf69,CALR,RALGPS2,BHLHE41,RPL39,PPP4R1,MSH2,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,SOCS5,TRAK2,PIGC,SPATA20,GFPT1,GCC2,PRODH,KCNJ12,CEP89,ADCK3,LPGAT1,CALM1,DCHS1,WHSC1,PYGL,EPHA1,ATP8B3,ANTXR1,JADE2,NFIB,PDE11A,MMP15,SLCO4A1,NT5C2,AP1AR,PLEKHH2,FAM64A,FAAH,PELI2,WDR19,ZDHHC20,MATN2,PIAS2,MPP2,FAM83D,APPL2,ARAP1,SFMBT1,CABIN1,KLK7,SAMD8,HOOK1,IFIH1,EHD1,MFSD3,FOXO6,SPRED1,KIF3C,DLGAP5,TCTN2,REPS2,ST14,THRA,RALBP1,CERCAM,NDRG1,ATP2C2,BLCAP,FTH1,BCL2L1,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPS8L2,EPM2A,NOV,CCNA2,RALB,RNASEH2A,PDE4D,EPHB4,TSPAN1,SULT2B1,FLOT2,NAGA,MED30,SEMA3B,ATG4D,DOCK4,FOXJ2,PANK1,KIF1C,ATP1B1,RAD17,PKMYT1,PYGO1,ASB13,CBL,B3GALNT2,ITPR3,ALCAM,ATP10D,FZD7,CEP162,ZMPSTE24,DDOST,ACAD10,NGFRAP1,TSPAN18,TRIOBP,SLC27A3,AREL1,COBL,PRKAR1A,PLSCR4,IGFBP6,DEPDC1,SLC41A1,CENPI,EPS8,NES,PBX3,HERC5,PLD2,FBXO6,SPDL1,DNAH3,FGF19,EFNB1,COX7A2,HLA-A,ADGRB2,SLC25A36,CKAP5,RASSF8,E2F7,GNB5,FJX1,FUT8,DRAM1,CD9,ERBB3,CITED2,TTPA,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,PAPD7,TCFL5,DIAPH2,FBXO9,YES1,FOS,ARSK,KIF11,CPTP,CRTC2,DCTN6,CDK5RAP1,ACADSB,FGFR2,TBX18,RIN3,ABCB1,RYK,ERAP1,RABL6,LRRK1,WDR62,FZD5,ESPL1,MELK,RGMA,CCNC,FAF2,UGT8,CRYM,UBE2Q1,VARS2,MPP5,MAP1LC3B,ERP29,SLC8B1,ECI1,TRIM68,HTR1D,EPCAM,ZFYVE16,RAB15,CDKL5,SIVA1,CEP78,TRPC1,ASH2L,CTTN,BTBD3,IL1RAP,CERS2,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,USP18,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,CAB39,GLA,CHPT1,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,PPP1R12A,BVES,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,SPP1,NOXA1,FAM20C,PFKL,OCRL,COL6A1,PRKCI,SRP54,BRAT1,LIMCH1,NPTN,HLA-C,C10orf54,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,PODXL2,SPA17,PDE5A,VWA1,NUBP1,STEAP1,RANBP9,MFSD7,RHPN1,INSR,UAP1,TMEM30A,RAB31,NXPH4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,DRD1,CCNE2,DYNLRB1,SORBS1,PAX6,HDAC11,SOD2,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,EXT2,SAP130,ARTN,CYP4F11,KIF14,REEP1,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,ETHE1,EBAG9,CHP1,CKS2,SOAT1,RFK,PTPRU,MRPS35,GLO1,CD40,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,HSF4,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,PTBP3,SPTBN5,RCAN2,MAD2L1BP,ABCA1,KDELC2,FBLIM1,GCLM,ENO2,TSPAN15,ARHGEF11,CIT,SHPRH,ARHGEF7,SERPINB9,TGFBR1,COL4A5,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,BMP7,MYCL,RRBP1,ZDHHC13,ACTA2,KANK2,RPGR,SLC35A1,MYO5A,B3GALT6,PGM1,WNT10B,CFAP46,RC3H2,RGCC,NADK2,TTC7A,RUNX3,NDRG3,FOXL1,LEPR,LEMD2,ARHGAP24,CTSL,CD8A,CASP7,SWAP70,RND3,TRIM69,CTSV,SPINT2,RAP2C,CSGALNACT1,DTX4,UACA,ARRB1,SLC18B1,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,CD33,NGEF,DOC2A,ACACB,KLK10,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,CACNA2D2,SMARCAL1,MMADHC,FBXO2,XIAP,NRG2,LGI3,IL18,CNTROB,MORF4L2,SYTL4,CA8,BARD1,KIF26A,TP73,CALM2,DAPK2,WEE1,ZYX,PSMD1,PQLC2,ARHGAP42,AP1M2,TGFBR3,RGS12,DNAH6,CYP2S1,ALDH1A3,SLC46A1,RDH14,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,APOBEC3G,TUBA4A,SPEF2,VPS11,SMARCA2,TNIP1,SPRTN,MTRF1L,LOXL2,ICMT,MYOM1,CYP4F3,COL12A1,SLC44A3,PGF,DNM1L,LIMK1,MYLK,MAP3K11,MRPS28,ARF6,E2F8,PDPR,GAB1,ALDH6A1,NFKBIE,TMTC3,NUAK1,CYP2J2,SOX9,SLC36A4,ZNRF3,MERTK,LMNA,ELF3,GNS,ZIC5,FAM13B,NEK2,STT3B,NCAM1,NDUFA12,NAGPA,UFD1L,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,ILK,TP53INP2,SPTLC2,RHOB,CYB5A,STK17A,PTPRF,NCOA3,MTFMT,SEMA4D,HTT,SETD3,TEX30,ITPR1,OSMR,AURKA,DYSF,MDH1,ALG2,B4GAT1,NDE1,ARPC2,TRPC3,RPS6KA3,CSRP2,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,TUBB4B,GALNT12,ACTR8,ETNK1,WDTC1,TESK2,PKP2,NUF2,IL13RA1,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,ENPP4,CAMSAP3,SSH3,PSRC1,LGALS8,FZD4,SYNE2,CDCA2,NUSAP1,PXYLP1,RAB38,IRS2,PEX5,SLC9A6,WWTR1,SIPA1L1,INPP4B,TRABD2A,PDXK,RGS14,GEN1,ARNT,TTC8,GALK1,FARP1,TNRC6C,TAOK2,NKX3-1,RBM24,MAN1A2,RASSF7,PDIA3,GMCL1,ANO9,PKN1,KCNC4,ETS1,GSTP1,TSPAN17,SRPX2,TIPRL,ICAM1,NEO1,PDIA4,DTX3L,CAPN2,CXCL16,ANK1,ADD3,SLC27A6,IRAK1,CTSC,ARSG,KCNK5,MCF2L,ALG13,CALD1,FDXR,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,MAPK11,AK3,SGCB,ITM2C,TPCN1,S100A6,TMX1,CRTAP,HCN3,AMOTL2,LCA5,FMN1,CTNNAL1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,PLEKHA7,EMP3,BLVRA,NEURL1B,SKA1,CRISPLD2,ABLIM2,TXK,GALNT3,PITX2,BTG1,KIAA0141,ATXN7L3,ACVRL1,NR1D2,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,CYBRD1,FOXA1,MYL9,SIGIRR,UNC93B1,AGRN,CUL4B,EPHA4,SUDS3,MCCC1,NDC80,CDIPT,HDAC6,PDGFB,SDC1,PIGL,PCNA,SHC3,CNTRL,ELF5,DUSP10,TNFRSF18,TLN2,ANO4,TRAM1,MYBL1,NEB,S100A13,CD55,ING1,MCTP1,C12orf65,EZR,ERP44,KLK6,PRKRA,ANLN,IDH1,CLCN2,ZBTB7B,CDK1,VCP,RHEB,PLEKHB1,OPTN,IRX3,DPYSL3,PLCH1,MSL1,MAP2,WIPI1,P4HA2,DOLPP1,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,POMT1,MAFF,PRKAA2,BMF,HLA-F,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,CORO1B,BMP2,RB1,DAZAP1,VASP,IGF1R,GATA2,PAK2,EXOC8,MDFIC,PLCB2,ALDH3A2,PSMA5,ABCC1,CYP26B1,CHSY3,MRPS33,TESK1,CORO2A,SPATA13,EIF2AK1,TCF7,IFIT3,UNC45B,ZDHHC3,G2E3,MAPKAPK2,H1F0,PVRL2,ITGA7,CSF1,MFSD2A,PRPS2,LTBP2,ATP1B3,TMEM120A,CTBP1,IFI6,NIPA1,RNF146,KCNAB3,AVPI1,NF2,UGP2,FOXM1,P3H2,XYLT1,DGKA,CCDC68,ERBB2,RASGRP3,SLC7A2,LPIN3,CYP26A1,SDF4,PER2,CDK14,RAD23A,ATP6V0B,SRPX,PLCG2,LHX6,SRR,GYS1,SCN2A,MINPP1,EGLN3,FAR1,GM2A,DVL2,CTH,SIRT1,TIMP2,MBP,EVA1A,FIGNL1,S100A4,CDC20,MYL12A,DNAJC10,DUOX1,RTN4RL1,ATP1A1,PSMD3,PTK7,ADAMTS14,ANXA9,RPL22,AIFM3,LTA4H,CNEP1R1,POMGNT2,NDST3,COPG1,ZC3HC1,GSDMD,COL9A3,MFSD14B,PACSIN2,TRAPPC10,ADGRG1,CD63,DAP,BLVRB,GNE,SWI5,GABRG2,PSMD10,SELL,JAG2,CRABP2,DSE,SIRPA,SLC9A2,PPP2R3A,GBX2,CEP97,SLC35B4,BUB1,ABCD1,FAIM,SLC45A3,CAMK2G,TLE6,FAH,DLGAP1,MLEC,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,CAPNS1,TRIM35,PELI3,AKAP3,FNDC3A,BCAR1,BORA,MAPK8IP1,SCRN2,PRDX4,CD83,FUCA1,BANK1,SERPINA1,FAT4,TWSG1,NMI,PGRMC1,PPP2R3C,PKD2,SPCS3,ACADM,NDFIP1,UBE2C,SUN1,GAA,CFAP74,ACVR1,ATP8A1,KLC2,TAP1,GATA3,PLXNA1,CCNB1,PLA2G16,SLC20A1,FAM101B,CENPN,NCS1,CHST2,CTGF,ELMO2,ZFP36,IL31RA,STEAP2,AOX1,ATRNL1,TFG,RCAN3,PACSIN1,XKR8,LAMP2,ORAI2,KIFC2,PBK,CASP9,MGAM,AGO4,TNS1,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,SPNS3,ARHGEF26,ULK2,SGPP1,SFXN1,KDSR,HLF,SLC25A4,AREG,PLK2,PTER,GNPTAB,TBX1,NKD1,DHTKD1,EIF4EBP2,UNC5B,TRAF5,RTN3,LZTS1,DLAT,DDX58,KLF2,MRPL44,INPPL1,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,NDUFA4,ISYNA1,SLC1A3,NOTCH2,KIAA1161,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,SLC16A6,NECAB3,BDH1,CTPS1,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,CTSD,TSPAN33,RIMS2,EEF1D,TMED2,DNAI1,EPB41L5,FADS2,DDB2,PMPCB,QSOX1,B3GNT7,MMD,B9D2,MICB,AMER1,ANO6,PTPRH,PIP4K2C,PKM,CYFIP2,KDM3A,FBXO10,RASA1,STX3,FRMD4B,FAS,DGKH,GABRD,PRKAG2,CSNK1G1,DCK,NAB2,SLC4A3,FGD6,NR4A2,EFNA1,MAP3K5,PKD1L2,IRF1,PLA2G4A,ELK4,SLC2A4,CEP70,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,CD274,EGR3,AIFM2,NUDT12,MNS1,GNB2,APLP2,DOK4,CNNM4,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,SLC5A11,TMEM43,CAPN6,DMTN,TEP1,COX11,SLC11A2,PRKCQ,AKR1E2,H2AFV,NIN,CMTM7,EPHA10,FYN,JAK1,PPP2R5A,STK26,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,MLKL,HS3ST3B1,B4GALT3,NR3C2,ATMIN,DENND5B,MRPS9,WASF3,ARHGEF3,SLC16A14,ATP9A,ARL4C,CDCA3,GPR180,CYB561,APOBEC3H,SPR,LGALS3BP,TEAD3,SIX4,RND1,SNTA1,OXCT1,PTEN,MGAT1,CENPJ,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,TAGLN2,CNOT6L,MAP3K7,GFI1,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,SMC4,PCCB,RASGRF1,ARAP2,SHMT1,CASK,MPP1,PARP4,VAMP3,FURIN,C1GALT1C1,GPLD1,RGS9,CTNS,PRDX3,SLC25A40,SERPINB5,PGM2L1,GRIN2D,GPER1,ARSB,NCAPG2,SLC25A38,OCLN,USP16,JARID2,EXPH5,EMX1,LTBP1,CASP3,NMRK1,CPT2,CAMKK1,EPHX4,UBE2Z,KIF2C,TAF6L,CACNB4,DNER,KREMEN1,TMC1,PTCHD4,SH3KBP1,ABCD4,CHPF,LRRC6,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,DLG1,CAPG,AKR1B1,SUN3,KIF22,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,TRIM8,SYNE3,STRIP2,FOPNL,RNF165,ROR1,MRPS18A,MRPS36,STK17B,ADRBK2,TCN2,EDNRA,MDK,CXXC4,NEIL1,FASTKD1,UEVLD,IARS2,ADIPOR1,APBA2,RAP1GAP,PSMC1,PPP2R5D,GRN,FAM213B,PIFO,LRRFIP2,PEX6,ELOVL7,ASL,ATP6V1E2,PHLPP1,CA2,LRRN2,KCNN4,DIAPH2-AS1,FNIP1,FXYD5,KNTC1,ACAD8,HP1BP3,KDELR1,PARD3B,GYLTL1B,BTN3A2,HMG20B,FBXO8,AMDHD1,EGFR,GLCE,FECH,GNAS,BCAR3,NUDT16,TSC1,ONECUT1,SLC6A6,PLPP3,UTP14C,CGREF1,PAPD5,NFKBIA,CDCA5,RHOBTB2,EGFL7,YOD1,PITPNA,KIF12,KLF7,FBXW5,GAS2L1,SLC25A24,SPC25,IL15,SLC2A8,PSME2,ABCG4,GMPR,TDRKH,ZMYND10,MICALL2,ARHGEF16,SLC25A48,SS18,SVBP,SETDB2,ZDHHC12,FRYL,SMO,GOT1,TWIST1,STEAP3,RPN2,APIP,F2R,PDIA6,LOXL1,SCYL3,HSPA2,FRS3,MAP3K3,TAF5,BAG4,KREMEN2,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CANT1,PLXND1,CYP2U1,SGOL1,REEP4,LIFR,PPP2R2D,ANXA3,CDS2,SORT1,JKAMP,FRMD6,POC1B,LRP4,AES,NOTUM,POMGNT1,SAC3D1,IL17RB,ADORA1,GALNS,KIAA0319,CKS1B,BRD7,IQGAP3,SUN2,SYPL1,ADAM17,RAB3B,CENPC,ASPM,GCLC,NR4A1,DEPDC4,OGDHL,POLD3,SPAG1,MAP1B,HLA-B,MARC1,DHRS2,TADA2B,UBE2D2,GLB1,HOXB13,GEM,ATP6V1C1,SOX8,L1CAM,SNPH |
| 5.791e-18 | -39.69 | large_intestine-rectum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-rectum-carcinoma-adenocarcinoma | 16676 | 2514 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,DMPK,WDR63,C5orf30,MGST2,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,HS6ST3,RRAGD,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,IL22RA1,PARM1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 5.836e-18 | -39.68 | bounding membrane of organelle | cellular component | GO:0098588 | 2293 | 478 | 17570 | 2579 |
SUN1,DOC2A,LAMP1,GAA,ACACB,SLC35D2,IL15RA,ATP8A1,DNAJC3,PNPLA2,RET,TAP1,SYTL4,PJA2,CHST2,NCS1,SLC9A7,PICK1,NAPG,PQLC2,CYP1A1,AP1M2,STIM1,CABP1,CYP2S1,RDH14,STEAP2,FUT1,DNM2,SNX16,MARCH2,TFG,CPE,MGAT5,ERAP2,LAMP2,VPS11,SPATA18,SNTB2,BNIP3L,SLC35C1,KDELR3,KIF13A,GALNT7,SLC17A5,MCFD2,ICMT,POR,CYP4F3,ULK2,RAB2B,SGPP1,KDSR,ENPP1,WDR11,AREG,DNM1L,GNPTAB,ATP7B,SARAF,ARF6,RTN3,SCOC,GGA1,SEC61G,HLA-E,CYP2J2,TMEM55B,RAB23,SLC36A4,NOTCH2,FAM21C,CALR,MARCH8,DOPEY2,RAC2,ZNRF2,SNX18,VASN,FLRT3,NECAB3,TPST1,PCYOX1,STT3B,CNGA1,NCAM1,PIKFYVE,MOXD1,PPP6R1,TMED2,GPR161,EPHX1,FAM69A,NAGPA,PIGC,QSOX1,FADS2,UFD1L,B3GNT7,MMD,LPGAT1,ERO1A,ATP8B3,MEST,SPTLC2,ANTXR1,GOLT1A,GNA11,RHOB,CYB5A,SCARB2,FAAH,ITPR1,ARAP1,APPL2,DGAT2,SAMD8,B4GAT1,ALG2,MAP3K5,PLIN3,TMEM173,EHD1,DMPK,PLA2G4A,ARMCX3,TCTN2,NLRX1,LFNG,GALNT12,NDRG1,APOO,ATP2C2,BCL2L1,MGST2,MVB12B,SNN,AIFM2,APC2,GNB2,KTN1,CYP39A1,ZFYVE9,CDS1,CD46,SCNN1A,ACAP2,XYLT2,ACSL4,TSPAN1,RAB27B,FLOT2,SNX10,TMEM9,TMBIM1,MX1,SNX8,SEC23A,SEC61B,ERMP1,COG2,FZD4,AGPS,DMTN,SYNE2,CYS1,CLSTN1,VPS4B,SLC11A2,SYP,PXYLP1,RAB38,DNAJB14,PKMYT1,ITPR3,B3GALNT2,TRIQK,ATP10D,ZMPSTE24,GABARAPL1,PEX5,DDOST,STX10,STK26,SLC9A6,WFS1,PNPLA6,HS3ST3B1,B4GALT3,NR3C2,TTC8,HSP90B1,ATP9A,TRAF2,MAN1A2,BACE1,FLOT1,CTSZ,PLD2,HLA-A,SGPL1,PDCD10,IRAK1,FUT2,CTSC,MGAT1,ALG13,MGAT4A,FUT8,FAM20B,DRAM1,BAX,CD9,SLC44A2,TMBIM6,PLEKHF1,MAP3K7,ITM2C,TPCN1,TMX1,MOB4,ACBD5,PDGFC,B3GNT2,CASK,ELOVL3,EIF5A2,FURIN,VAMP3,C1GALT1C1,CPTP,GPLD1,GALNT3,NUCB1,PROM1,LDLRAP1,CTNS,PLOD2,SYT7,RAB11FIP2,SLC35B3,ARFGAP3,ERAP1,GPER1,FZD5,WDR45B,ESYT2,UNC93B1,FAF2,EPHA4,ARFGEF1,ITPR2,MGAT5B,CDIPT,PIGL,MAP1LC3B,PDGFB,CHPF,ABCD4,ZFYVE16,RAB15,INPP5E,ENTPD4,NUP210,TM9SF2,LMAN2L,ARL1,SLC44A1,DLG1,ABCA2,RAB20,TECR,PXMP4,SCARA3,MYRIP,TRAM1,RASGRP1,CERS2,LAMP3,CYP1B1,ATL1,SYNE3,ACBD3,NFE2L1,ERP44,ESYT1,PTGFRN,VCP,RHEB,OPTN,MAN2A2,HS6ST1,AGPAT2,HPSE,WIPI1,DOLPP1,RAB11FIP1,PIEZO1,TTC9,POMT1,CHPT1,NRGN,RAP1GAP,RRAGD,STARD3NL,BMF,LMTK3,PEX6,FXYD3,HLA-F,ELOVL7,RAB6A,B4GALT4,DHRS3,QSOX2,PGAP1,B4GALNT1,B3GALNT1,OCRL,SLC30A6,COL6A1,PRKCI,SUCO,SELK,HLA-C,TMEM8A,WNT3A,FAR2,GAD1,MPHOSPH9,ALDH3A2,CKAP4,KDELR1,CHSY3,CYP26B1,MGAT4B,GYLTL1B,EMC2,C3orf58,STEAP1,ZDHHC3,C18orf8,EGFR,GLCE,MOSPD3,GNAS,INSR,FA2H,MFSD2A,TMEM30A,PHLPP2,PLPP3,RAB31,ZDHHC7,CTSA,PLD1,APOL2,DRD1,PROM2,SLC2A8,XYLT1,PDIA5,ERBB2,FAM198B,LPIN3,EMP2,EXT2,BCAP31,CYP26A1,PDGFA,ATP6V0B,CYP4F11,WDR44,REEP1,SMO,VAT1,STEAP3,RPN2,ECE1,NOTCH3,LMAN1,PDIA6,FAR1,EBAG9,CHP1,SOAT1,CLCN3,EVA1A,KREMEN2,OSTM1,C3orf52,AP5M1,TMTC2,CASP4,ATP13A2,PTGS2,TAPBP,PEX2,MAOA,CANT1,SPTBN5,IRF7,CHMP4B,CYP2U1,REEP4,ST3GAL1,POMGNT2,NDST3,COPG1,FAM134B,ARFGEF3,MAN2B2,ANXA3,PINK1,PACSIN2,GOLIM4,CDS2,SORT1,TRAPPC10,TAB3,CD63,SCD5,JKAMP,POMGNT1,DSE,LBR,ITGA2B,PARM1,VPS26A,DNAJB9,M6PR,TMEM63A,ZDHHC21,SNX13,A4GALT,RRBP1,KIAA0319,SLC35B4,ZDHHC13,UBE2J1,SGK1,ABCD1,SLC35A1,CAMK2G,GCNT1,B3GALT6,P2RX4,SUN2,RHOA,MLEC,RAB3B,IFITM3,PLAUR,AMFR,SYBU,LITAF,COL7A1,CARD19,FNDC3A,BBS2,TXNDC11,MAPK8IP1,HLA-B,MARC1,SERPINA1,RND3,RAP2C,CSGALNACT1,PGRMC1,ARRB1,PKD2,SPCS3,PLOD3,ATP6V1C1,NDFIP1,PTGES,ABCG1,GOLGB1 |
| 7.751e-18 | -39.40 | rectum | COSMIC cancer mutations | rectum | 16679 | 2514 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,DMPK,WDR63,C5orf30,MGST2,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,HS6ST3,RRAGD,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,IL22RA1,PARM1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 9.998e-18 | -39.14 | PHONG_TNF_RESPONSE_NOT_VIA_P38 | MSigDB lists | PHONG_TNF_RESPONSE_NOT_VIA_P38 | 329 | 109 | 17758 | 2588 |
TRIP10,DNAJC3,CUL4B,SOD2,TGOLN2,PLXNA1,OSR2,CYP1A1,SP100,RGS3,PPME1,IL6ST,N4BP3,CDKN1B,IRF2,MANF,PIK3CD,ECE1,NFKB2,MYBL1,NR2C1,MAP3K3,DOCK4,PPIF,COL6A2,HN1L,TNIP1,RIPK2,NFE2L1,LOXL2,ATP1B1,RNF19B,ABR,OPTN,IRS2,DNAJC10,JAK1,RBM47,GPRC5B,P4HA2,LRIG1,INPP4B,ABCA1,HSP90B1,PARP12,SDC4,SOX9,FLOT1,EFHD2,CYB561,DSE,ARHGEF40,ETS1,ICAM1,NRP2,HLA-A,PDIA4,ZNF432,RAC2,GATA2,CALD1,BHLHE41,AIM1,COL6A1,DRAM1,SGK1,TRIM21,CD70,RFX5,HLA-C,CLIP2,TRIM62,TPCN1,IGSF3,MDFI,AMOTL2,NFE2L3,HES1,MMD,PRSS23,RAPGEF2,PLAUR,MGAT4B,STEAP1,EGFR,BSDC1,CD83,CNOT2,HLA-B,TMEM50B,SLCO4A1,SERTAD2,ETS2,RAB11FIP2,DHRS2,CSF1,NFKBIA,NMI,SLC2A6,NETO2,SH3BP4,ARRB1,EFNA1,GEM,FZD5,PTGES,KLF7,IRF1,EHD1 |
| 1.157e-17 | -39.00 | GOLDRATH_ANTIGEN_RESPONSE | MSigDB lists | GOLDRATH_ANTIGEN_RESPONSE | 334 | 110 | 17758 | 2588 |
CASP3,TXN,TTC39B,DLGAP5,S100A11,GNPDA1,KIF2C,CCNB1,IER3,CDKN2C,WEE1,PCNA,CCNA2,SP100,UBE2T,SIVA1,PLCG2,CAPG,PLK4,KIF22,TMEM37,F2R,SNX10,HSPA2,S100A13,CKS2,PLK1,CENPA,FIGNL1,S100A4,SH3BGRL,DSTN,CDC20,PTGER4,NUSAP1,AURKB,CCNF,ANLN,DOCK5,H2AFV,CDC25C,ALCAM,CDK1,PRIM1,CARHSP1,FYN,SERPINB6,KPNA2,RELL1,E2F8,CD99,RUNX2,LGALS3,CKAP2,GCAT,SERPINB9,CDCA3,CDCA8,EFHD2,RACGAP1,IL18R1,SSX2IP,HLA-A,LMNA,TOP2A,CAPN2,CA2,CST3,AIM1,PRC1,NEK2,CKS1B,BUB1,MDFIC,MXD3,PIM1,NPTN,AK3,IQGAP3,CTSD,CITED2,KANK3,SGCB,S100A6,DUSP1,WBP5,SYPL1,PLSCR1,PQLC3,KIF20A,IFITM3,ASPM,LITAF,FHL2,EMP3,GGH,KIF11,C4orf27,PRDX4,GALNT3,H1F0,TMEM30A,CDCA5,DBI,AURKA,GEM,CCNB2,CBX5,ACOT7,RAD21 |
| 1.295e-17 | -38.89 | regulation of molecular function | biological process | GO:0065009 | 2753 | 561 | 16441 | 2455 |
ADD1,IBTK,TRIM5,DNAJC3,RET,XIAP,NRG2,SNX9,CARD10,GRM5,TP73,NPM2,CALM2,CDKN2C,PSMD1,ARHGAP42,RGS12,TGFBR3,CABP1,PPP1R16A,DNM2,CRY2,TIAM1,NEK4,PRKAR2B,PPP1R14C,ARF4,ABR,PLCG1,MID1IP1,CAMK2N2,LIMK1,NOD2,MAP3K11,AGFG2,SERPINB6,HSPB1,STARD13,GAB1,NUAK1,ITGA6,GPSM2,TFAP4,RAC2,FBXO7,FAM13B,RANBP1,NEK2,MAP3K9,NCAM1,MAPK7,PPP6R1,MAPKAPK3,ILK,PSMA4,PLIN5,PTPRF,NCOA3,FNTA,HTT,SEMA4D,ITPR1,AURKA,STK39,SERPINB1,RPS6KA3,TMEM173,XDH,EGLN1,DOCK9,DMPK,ARHGAP11A,GRHL2,NQO1,LFNG,PTTG1,WDTC1,RGS20,MGST2,PRKACA,CCND1,ST5,SP100,SH3BP1,TAX1BP3,DLG3,RASGEF1A,CDKN2D,CAMSAP3,PSRC1,RIPK2,NRBF2,FZD4,PFKFB2,GTF2A2,EBF2,IRS2,CCNB3,WFS1,CORO1C,WWTR1,SIPA1L1,PLEKHG1,RGS14,MAPK12,CTHRC1,TCAF1,FARP1,NKX3-1,TAOK2,HSP90B1,TRAF2,HABP4,SDC4,FLOT1,ANO9,PKN1,GSTP1,ARHGEF40,TIPRL,ICAM1,CTNNBIP1,DIRAS3,PDCD10,IRAK1,CTSC,KNDC1,GPC3,MCF2L,CST3,BAX,ADAM15,TMBIM6,MAPK11,RAG1,PLSCR1,RAPGEF2,PIK3R1,GRIN1,RAB3IP,TXK,LDLRAP1,KIAA0141,ARFGAP3,CENPE,FHL1,CD81,FOXA1,SIGIRR,AGRN,EPHA4,ARFGEF1,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,SPTB,PCNA,CTNNB1,RABEP2,NPNT,SHC3,ARL1,PSMC2,DUSP10,RGS5,ZNF462,PLK1,PRKRA,CDK1,VCP,KDM4D,PLEKHG6,TBC1D17,LMTK3,HJURP,FXYD3,RASA2,UBASH3B,PSMD7,RACGAP1,DOCK11,FBLN1,BMP2,RB1,TIMP1,IGF1R,RINL,PAK2,TBCD,MDFIC,PIM1,WNT3A,PLCB2,PSMA5,SPATA13,STRADB,SCRIB,BCL2L13,CDK5R1,RASGRP2,MAPKAPK2,CSF1,NLRC5,ATP1B3,IFI6,AVPI1,NF2,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,EMP2,STIL,BCAP31,SYTL2,PER2,PDGFA,PPME1,PLCG2,BCL6,CDH3,TMEM64,OAS3,EGLN3,GM2A,DVL2,CTH,SIRT1,PPIF,TIMP2,AKT1,CDC20,C3orf33,DNAJC10,PTPRJ,RBL1,MMP17,PSMD3,STK38,EFNA5,ARHGAP4,ARFGEF3,PINK1,TAB3,DAP,CTSB,GNAL,PSMD10,AIP,PARM1,PPP2R3A,FZD6,SH2D4A,ZDHHC21,CD109,SGK1,TRIM21,BUB1,HEXIM2,SYK,CAMK2G,DUSP1,HES1,RHOA,PSMB4,AMFR,PLAUR,PPARA,STMN3,COL7A1,MAPK8IP1,BCL10,DDAH1,SERPINA1,FGF18,NETO2,E2F1,PPP2R3C,PKD2,NDFIP1,TBC1D4,UBE2C,HIPK3,ARHGEF9,PKIA,ARHGEF4,PPP4R4,TXN,GATA3,CUL1,PSME1,CAMK1D,CCNB1,ELMOD2,RIC1,PAK6,CTGF,STIM1,RGS3,PIK3CA,SERINC2,RCAN3,ACVR1C,CASP9,AURKB,PIF1,SAV1,POR,ARHGEF26,SH2D3C,PLK2,PPP2R4,SERPINI1,TRAF5,FGD1,DDX58,CDKN1C,TBC1D1,PRKAA1,BMP2K,SH3RF2,RALGPS2,CYR61,SNX18,PPP4R1,PRKG1,DAPK1,MSH2,SORL1,CACNA1D,GPR161,TMED2,SOCS5,EPB41L5,MMD,TBC1D8B,CALM1,EPHA1,CYFIP2,NFIB,RASA1,FAS,MMP15,PRKAG2,ARAP1,PIAS2,FGD6,CABIN1,NR4A2,EFNA1,MAP3K5,PLEKHG3,SPRED1,THRA,IQGAP1,CAST,RALBP1,RPS6KA1,FLT3,EPS8L2,CD46,APLP2,ACAP2,CCNA2,RALB,FICD,CDKN1B,DAB2IP,IFIT1,PDE4D,TMBIM1,TBC1D10B,DOCK4,UTRN,COX11,PRKCQ,SLC11A2,PKMYT1,ATP1B1,ITPR3,FYN,PPP2R5A,JAK1,STK26,NGFRAP1,KIAA1804,SLC27A1,NRG1,PRKAR1A,DENND5B,PCOLCE,ARHGEF3,DEPDC1,HERC5,NES,SPR,FGF19,WWP2,GNB5,PTEN,PPP1R10,SGK3,ERBB3,ERCC2,MAP3K7,GFI1,TRIM62,SPRY2,MSH6,NCOA2,FARP2,PDGFC,RASGRF1,ARHGEF28,ARAP2,DENND1B,FURIN,GRTP1,FOS,GPLD1,CRTC2,CDK5RAP1,RGS9,TIMP3,PRDX3,RCBTB2,FGFR2,RIN3,SERPINB5,GRIN2D,GPER1,FZD5,CPEB2,CCNC,CASP3,FAF2,CAMKK1,TAF6L,ERP29,CACNB4,DENND2D,ARHGEF10L,SIPA1L2,ARHGEF37,CDKL5,SIVA1,DLG1,RP2,SLC39A10,RASGRP1,CYP1B1,SOD1,TRIM8,ITCH,ARHGDIB,EDNRA,SEC14L2,NEIL1,ARHGEF19,GPRC5B,MADD,CAB39,GLA,RAP1GAP,PPP2R5D,PSMC1,PIFO,ARAP3,PPP1R12A,SERPINE2,PPP1R2,BVES,CALM3,DUSP5,NOXA1,OCRL,PRKCI,FXYD5,FNIP1,ALS2CL,CCDC88A,MDFI,FBXO8,PDE5A,RHPN1,EGFR,BCAR3,GNAS,TSC1,INSR,PLPP3,NFKBIA,SH3BP4,DCUN1D1,CTSA,JAK3,PROM2,DRD1,CCNE2,PSME2,ARHGEF16,KIF14,SMO,TWIST1,NFKB2,F2R,HSPA2,CHP1,CKS2,FRS3,MAP3K3,BAG4,RFK,ERBB2IP,CD40,DUSP4,DOCK5,CDC25C,MAP3K6,SOCS3,ARHGAP35,RCAN2,SPTBN5,PLXND1,PPP2R2D,GCLM,ANXA3,SORT1,ARHGEF11,ARHGEF7,SERPINB9,AES,TGFBR1,TRIB2,SBF1,SYDE2,SNX13,CARD8,ADRBK1,ADORA1,LLGL2,BMP7,H2AFY,CKS1B,IQGAP3,RPGR,MYO5A,ADAM17,WNT10B,RGCC,LEPR,ARHGAP24,CASP7,RAP2C,SPINT2,ARRB1,RAB3IL1,NGEF |
| 1.818e-17 | -38.55 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | 436 | 132 | 17758 | 2588 |
AGRN,EPAS1,AASS,GATA3,PDGFRL,BAIAP3,SEPT4,OAT,NUP62CL,CYP1A1,RPS6KA2,ALDH1A3,TMEM143,TUBG1,PIK3CD,TLN2,MYBL1,LAMP3,CYP1B1,ING1,TFAP2C,PRKAR2B,CCNF,POR,PGF,HPSE,AREG,ANKRD6,PLK2,EIF4EBP2,SERPINI1,NRGN,GRN,KLF2,CDKN1C,SERPINE2,ITGA6,CNTNAP2,GPSM2,BMP2K,GNS,SPP1,TIMP1,RUNDC3B,NCAM1,ULBP2,TTLL1,CYP26B1,PLS1,KIAA1109,SPTLC2,RHOB,GLCE,RASGRP2,H1F0,ITGA7,CGREF1,NAB2,FGD6,NR4A2,CDK18,IFI6,CSRP2,SORBS1,DLGAP5,IL15,GMPR,IL13RA1,KCTD12,MICALL2,IER3,APLP2,CDH1,BCL6,IFIT1,HSPA2,GM2A,CTH,COL6A2,S100A4,SAT1,PTGER4,ATP1B1,ALCAM,ATP13A2,NGFRAP1,STAT1,LIFR,BIN1,DYRK3,SORT1,HABP4,SDC4,BIK,JAG2,DSE,DNAH3,SEPP1,TOP2A,RNF128,ALPP,RRBP1,FDXR,CD9,SGK3,TSPAN13,CLIP2,WBP5,DUSP1,HES1,ALDH2,NR4A1,CRIP2,OGDHL,CXorf57,FOS,CRISPLD2,MAPK8IP1,FUCA1,BTG1,TIMP3,SWAP70,ACADSB,DHRS2,NAT1,ABCB1,SERPINB5,FHL1,FZD5,L1CAM,AHR,ACOT7 |
| 1.981e-17 | -38.46 | COLDREN_GEFITINIB_RESISTANCE_DN | MSigDB lists | COLDREN_GEFITINIB_RESISTANCE_DN | 217 | 82 | 17758 | 2588 |
EXPH5,LMO7,FAM171B,GRHL2,REPS2,ST14,ATP2C2,PRSS22,DDR1,TMPRSS4,EPS8L2,C1orf116,CDS1,WEE1,AP1M2,CDH1,GRHL1,NPNT,ALDH1A3,ENPP5,CLDN4,CDH3,TACSTD2,MYH14,TSPAN1,SMAGP,ENPP4,GCA,KIAA0040,KLK6,ARHGDIB,RAB38,SLC44A3,KCNMB4,RBM47,CCDC149,OVOL1,CAB39,MAPK13,ANXA9,GAB1,TC2N,PRSS8,MACC1,CYP2J2,FXYD3,BIK,CCDC64B,SRPX2,PRRG4,ELF3,ZDHHC21,AIM1L,WDFY1,AIM1,KLC3,HMGCL,FAM84B,ERBB3,PVRL4,ARAP2,TBC1D8B,PLEKHA7,PDE5A,EPHA1,FRMD4B,GALNT3,EPN3,ENDOD1,GNAS,TMEM54,TJP3,TMC5,FAM3C,C1orf21,SERPINB5,STK39,SH3BGRL2,MAL2,GRAMD1C,FOXA1,OCLN |
| 4.221e-17 | -37.70 | WONG_ADULT_TISSUE_STEM_MODULE | MSigDB lists | WONG_ADULT_TISSUE_STEM_MODULE | 694 | 184 | 17758 | 2588 |
MYL9,LTBP1,TXN,PPFIBP2,CACNA2D2,GATA3,NDRG2,IL18,TP53I11,SYTL4,FAM101B,SDC1,SLC35E4,LTBP3,ZNF275,PLS3,DAPK2,BTG3,CTGF,TSPAN6,FOSB,MITF,RAB20,RGS5,TINAGL1,RCAN3,PACSIN1,IL10RB,S100A13,CYP1B1,SMARCA2,SGCE,CXXC5,TMEM98,KDELR3,CR2,SESN1,STK17B,AHRR,TRIM47,HLF,MPRIP,GPRC5B,MAP2,PLK2,TBX1,HOXA9,MYLK,PRDM5,PRKCDBP,NFKBIZ,LSM14B,KLF2,CDKN1C,DNAJB2,ABCG2,NCKAP1,PHLPP1,IL18R1,MYO5C,CYR61,GATA2,PAIP2B,COL6A1,AIM1,TPST1,SORL1,MDFIC,LIMCH1,NCAM1,MOXD1,SLC12A2,DGKG,ABCC1,PAQR7,PQLC3,PRSS23,TESK1,STAT4,NFIB,RHOB,IL1R1,SLC6A6,ETS2,NFKBIA,NAB2,MATN2,DCUN1D1,NR4A2,LTBP2,ZDBF2,SERPINB1,IFIH1,TOB1,SNX30,IL15,HDAC11,DGKA,ETNK1,COL18A1,FLT3,PHLDA1,KTN1,IER3,PDGFA,CCND1,DAB2IP,IFIT1,EPHB4,EPB41L4B,DLG3,F2R,SNX10,HSPA2,TMBIM1,SLC39A8,S100A4,PTGER4,PRKCQ,RAB38,DUSP4,CD40,ALCAM,CASP4,GABARAPL1,NFIX,SOCS3,ARHGAP35,PTGS2,FYN,JAK1,PDLIM3,C19orf66,MMP17,TLE1,IRF7,RCAN2,ARHGAP4,ABCA1,CBX4,FAM134B,COL9A3,NKX3-1,MPZL1,GCAT,FRMD6,SLC41A1,LRP4,EPS8,FLOT1,PBX3,CTSZ,LGALS3BP,DNAJB9,ICAM1,CAPN2,GNB5,CALD1,RRBP1,KLF9,CITED2,NPTXR,TTPA,ITM2C,S100A6,WBP5,DUSP1,P2RX4,IFITM3,NR4A1,RC3H2,STMN3,YES1,FOS,TIMP3,ZFP30,PKD2,FHL1,GEM,L1CAM,PKIA,FOXA1,PHC1,ABCG1 |
| 4.538e-17 | -37.63 | urinary_tract-bladder-carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma | 14745 | 2286 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,KIAA1147,MUC16,ENPP5,ZNF365,MYT1,SNX8,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,SLC25A30,CTHRC1,HSP90B1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,FLOT1,BTN3A1,CTSZ,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,IRF7,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,PNISR,LGR4,SSH1,HSPG2,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,DOPEY2,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,NAGA,ATG4D,DOCK4,PANK1,UTRN,KIF1C,PKMYT1,PYGO1,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,ARSK,KIF11,ACADSB,DGCR2,FGFR2,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ADAMTSL4,DUSP5,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,UAP1,SPAG7,DCUN1D1,RAB31,CTSA,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,SLC46A1,KLF3,FUT1,SEMA3G,ODF2L,NWD1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,TRIM2,AGRN,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ASAH1,DOCK11,PGAP1,BMP2,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,NF2,UGP2,DGKA,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,NKD1,DHTKD1,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,ZNF84,MMD,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,GNB2,TMPRSS4,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,OCLN,NMRK1,HEBP1,CAMKK1,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,KCTD15,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,IBTK,GRIK2,AK7,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,RABGGTA,TFAP4,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,KANK3,DGKG,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,C11orf45,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PSMC2,MITF,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CCBL2,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,KPNA2,TC2N,RRAGD,HS6ST3,PRSS8,RMND5A,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,ST3GAL1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,HMGN3,GDF15,LBR,AIP,VPS26A,PARM1,FZD6,SH2D4A,NRP2,CD109,CDK16,ALPP,FAM63A,TFAP2A,SGK1,TRIM21,SYK,WBP5,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,CAPN12,REPS2,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,ABCB1,WDR91,FZD5,MELK,UGT8,ERP29,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,QSOX2,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,CEP41,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,KIF26A,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,LIMK1,MAP3K11,SERPINB6,RELL1,E2F8,GAB1,HOXC13,NFKBIE,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,MYBL1,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,EPB41L4A,GLCCI1,BMF,RACGAP1,CNTNAP2,B4GALT4,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,CTH,CPD,MBP,FIGNL1,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,SELL,GABRG2,JAG2,DSE,GBX2,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,CCDC34,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,FAM101B,CENPN,CHST2,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,PRRG4,BMP2K,ITGA3,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,CASP3,LTBP1,ST13,EPHX4,KIF2C,DNER,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,RASGRP1,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,ZNF432,AIM1L,CA2,LRRN2,FNIP1,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,PAPD5,EGFL7,PITPNA,FBXW5,GAS2L1,SLC25A24,ZSWIM5,PSME2,SLC2A8,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,HNRNPH2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 7.173e-17 | -37.17 | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | 632 | 171 | 17758 | 2588 |
UNKL,LTBP1,GAA,FAF2,TMEM184B,SSH1,HSPG2,TMEM41B,TEX2,PLXNA1,CDIPT,SDC1,SLC20A1,LTBP3,CMTM6,CHPF,PQLC2,TGFBR3,TM9SF2,IL6ST,TSPAN6,ZFP36,SLC46A1,KIF22,TINAGL1,MANF,SLC39A10,RNF26,CERS2,PLK1,ESYT1,ICMT,POR,SGPP1,KDSR,TRAM2,GPRC5B,DHRS13,P4HA2,TRIM45,BMP1,PIEZO1,GLA,RTN3,GRN,MRC2,PSMD7,ZNRF3,GNS,ITGA3,IGF1R,VASN,KCNN4,SLC30A6,TNFRSF12A,NPTN,NCAM1,CTSD,CKAP4,ABCC1,NAGPA,QSOX1,PCDH1,PRSS23,RGMB,ANO6,SPTLC2,NFIB,PTPRF,FAM64A,PVRL2,HTT,CSF1,FAM83D,PCDH19,EFNA1,LTBP2,CDAN1,TMEM173,IQGAP1,PDIA5,ERBB2,TMEM19,DDR1,TNFSF9,BCAP31,EXT2,ATP6V0B,APLP2,STEAP3,EPHB4,ECE1,MINPP1,NFKB2,LMAN1,PDIA6,CPD,SOAT1,ERMP1,TIMP2,TMEM43,CDC20,CLSTN1,SLC11A2,IGSF8,PKMYT1,ITPR3,DAG1,ATP10D,FZD7,ATP1A1,DDOST,ABHD12,AXL,SLC9A6,CANT1,PCOLCE,TM2D2,CDS2,IGFBP6,MPZL1,JKAMP,SLC41A1,PDIA3,CTSZ,COL4A5,SBF1,EFNB1,NRP2,NEO1,PDIA4,TMEM63A,SGPL1,M6PR,CD109,MGAT1,CST3,SLC35B4,CD9,DRAM1,SLC44A2,TMBIM6,IL17RA,ITM2C,CNPY3,CRTAP,DUSP1,HMMR,AMOTL2,B3GALT6,ADAM17,MLEC,GUSB,TTC7A,TRIM35,PIM3,FAM73B,TXNDC11,PRDX4,ENDOD1,RPL12,CTNS,DGCR2,PLA2G15,ARFGAP3,WDR62,PLOD3,CD81,PTGES,DCBLD1,ESYT2 |
| 7.702e-17 | -37.10 | KOBAYASHI_EGFR_SIGNALING_24HR_DN | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_DN | 242 | 87 | 17758 | 2588 |
CCNE2,SPC25,DLGAP5,TUBB4B,NDC80,KIF2C,CCNB1,SLC20A1,BARD1,PHLDA1,STIL,CENPN,CARD10,FANCI,IER3,CCND1,PCNA,CCNA2,KIF14,PLK4,TUBG1,ACOX2,RNASEH2A,MYBL1,CKS2,PLK1,PPIF,PSRC1,CENPA,PBK,CDC20,NUSAP1,AURKB,PKMYT1,DUSP4,CCNF,CDK1,PRIM1,CDCA4,AREG,AXL,WWTR1,NRG1,KPNA2,MAFF,E2F8,HJURP,DEPDC1,ENO2,ITGA6,ETV5,SOX9,CDCA3,CDCA8,ERCC6L,KIF23,RACGAP1,GPSM2,DUSP5,TOP2A,FAM111A,RANBP1,PRC1,MSH2,NEK2,CKS1B,TNFRSF12A,USP1,BUB1,MSH6,SMC4,HMMR,ZWINT,ASPM,MYBL2,KIF11,STEAP1,SLCO4A1,FAM64A,NETO2,E2F1,AURKA,DONSON,NCAPG2,UBE2C,ESPL1,MELK |
| 7.745e-17 | -37.10 | vesicle | cellular component | GO:0031982 | 3622 | 693 | 17570 | 2579 |
DOC2A,KLK10,IL15RA,DNAJC3,HEXB,FBXO2,TRAPPC8,TGOLN2,LGI3,IL18,LYNX1,SYTL4,SNX9,CMTM6,LTBP3,GRM5,EPDR1,CALM2,DAPK2,NAPG,PSMD1,AP1M2,TGFBR3,MUC4,ALDH1A3,DNM2,SEMA3G,PPP1CA,TINAGL1,IL10RB,CPE,MGAT5,TUBA4A,VPS11,SH3BGRL,DSTN,RNF11,PRKAR2B,F12,ARF4,LCP1,COL12A1,CARHSP1,DNM1L,ATP7B,MYLK,NOD2,SERPINB6,ARF6,HSPB1,ANXA11,ALDH6A1,CYP2J2,RAB23,TTYH3,MARCH8,GNS,SH3D21,RAC2,CD22,ATP5H,MEGF8,PCYOX1,CADPS2,MYDGF,NCAM1,C9orf72,PLS1,MEST,TP53INP2,PSMA4,GNA11,RHOB,CYB5A,PTPRF,NAAA,SCARB2,NCOA3,SLC4A4,HTT,APMAP,ITPR1,DYSF,MDH1,MAL2,B4GAT1,ARPC2,CFAP20,SERPINB1,TMEM173,RUSC1,MTM1,NQO1,TUBB4B,LFNG,CD82,MVB12B,PRKACA,APPBP2,MUC16,SCNN1A,CDH1,TAX1BP3,ACSL4,RAB27B,ENPP4,COL6A2,RIPK2,LGALS8,NRBF2,FZD4,SEPT6,SYNE2,CYS1,VPS4B,SYP,RAB38,SNX12,GABARAPL1,ALDH3B1,STX10,CORO1C,SLC9A6,AXL,PDXK,GEN1,ISOC1,GALK1,TAOK2,HSP90B1,MAN1A2,BACE1,TRAF2,SDC4,FLOT1,PDIA3,CTSZ,PKN1,NUCB2,GSTP1,ICAM1,PDIA4,CAPN2,PDCD10,FUT2,ITGB8,CTSC,GPC3,MGAT4A,CST3,TUBGCP6,BAX,ADAM15,WWP1,IGFBP2,ITM2C,S100A6,AMOTL2,PVRL4,PLSCR1,RAPGEF2,DUSP23,GRIN1,PLEKHA7,AK4,BLVRA,FAM109A,CRISPLD2,GALNT3,LDLRAP1,RPL12,PROM1,PLOD2,RAB11FIP2,SYT7,DBI,FAM3C,PLA2G15,ITGAV,CD81,CYBRD1,ACOT7,UNC93B1,BCAM,AGRN,GNPDA1,CUL4B,NDRG2,F11R,GALM,PDGFB,SDC1,SLC9A3R2,SUSD2,CPNE2,PCNA,ENTPD4,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,LMAN2L,SLC44A1,ABCA2,NEB,S100A13,SMAGP,THRB,CD55,CR2,EZR,ERP44,IDH1,CDK1,VCP,RHEB,OPTN,DPYSL3,TRIM9,TBC1D17,WIPI1,RAB11FIP1,ARRDC1,CTNND1,PIK3C2B,POMT1,MYL12B,PRSS8,BMF,LGALS3,FXYD3,HLA-F,PSMD7,ASAH1,RACGAP1,RAB6A,NCKAP1,FBLN1,ANO1,CORO1B,MYO5C,VASP,TIMP1,RINL,FCHO1,AHCY,TMEM8A,WNT3A,ALDH3A2,CKAP4,PSMA5,ABCC1,C9orf9,PCBP3,SCRIB,MAPKAPK2,EPN3,PVRL2,CSF1,PRPS2,FAM213A,LTBP2,ATP1B3,PLD1,UGP2,CTDSPL,ERBB2,EMP2,PCBP1,BCAP31,C1orf116,SYTL2,SDF4,PDGFA,ATP6V0B,EFR3A,PLCG2,N4BP3,VAT1,MINPP1,LMAN1,GM2A,DVL2,CTH,CPD,CLCN3,TIMP2,TCEB2,AKT1,FIGNL1,S100A4,ACO1,MYL12A,DAG1,ATP13A2,RTN4RL1,PTPRJ,ATP1A1,PAFAH1B3,PSMD3,CHMP4B,ANXA9,SYT13,RPL22,LTA4H,ST3GAL1,COPG1,ARFGEF3,CTDSP1,MAN2B2,PACSIN2,GOLIM4,ADGRG1,CD63,TAB3,RUSC2,CTSB,BLVRB,GNAL,GDF15,CRABP2,VPS26A,DNAJB9,FZD6,SIRPA,CDK16,FAM63A,ALDH7A1,SYK,CAMK2G,ATP2B1,FAH,P2RX4,FBLN5,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,COL7A1,CAPNS1,GGH,FXR2,AKAP3,FNDC3A,RNPEP,SCRN2,PRDX4,DDX23,FUCA1,DDAH1,SERPINA1,FAT4,TWSG1,SCG2,TMC5,PGRMC1,PKD2,SH3BGRL2,ACADM,ICOSLG,TBC1D4,SAT2,LAMP1,SUN1,GAA,TXN,HSPG2,ATP8A1,FAM129B,PSME1,NANS,PLXNA1,PICK1,NCS1,STEAP2,SERINC2,AOX1,TACSTD2,MTMR11,MARCH2,PACSIN1,TFG,LAMP2,LOC81691,SNTB2,HSPA12A,MGAM,SLC17A5,GALNT7,MCFD2,SLC25A5,TP53I3,RAB2B,ULK2,AREG,PTER,PPP2R4,BMP1,SERPINI1,RTN3,HLA-E,NDUFA4,APBA1,CALR,DOPEY2,ITGA3,SNX18,ZNRF2,VASN,SORL1,CYSRT1,CD70,OSTF1,PIKFYVE,CTSD,SYTL3,GPR161,RIMS2,TMED2,GFPT1,QSOX1,KLK5,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,PYGL,VEZT,NPC2,ATP8B3,CYFIP2,PKM,JADE2,ANTXR1,STX3,FAS,AP1AR,ARAP1,APPL2,KLK7,EFNA1,EHD1,PLA2G4A,SLC2A4,GPR107,S100A11,TRIP10,ST14,NDRG1,IQGAP1,BROX,FTH1,KCTD12,CD274,BCL2L1,DDR1,GNB2,EPS8L2,CD46,APLP2,RALB,DAB2IP,EPHB4,LGMN,TSPAN1,SULT2B1,FLOT2,NAGA,TMBIM1,GPX4,SEMA3B,MYO5B,SEC23A,DMTN,CLSTN1,UTRN,SLC11A2,ATP1B1,AKR1E2,H2AFV,ALCAM,ZMPSTE24,EPHA10,ACYP1,STK26,PPP1CB,RAB29,B4GALT3,WASF3,PLSCR4,PCOLCE,IGFBP6,EPS8,GPR180,PLD2,SEPP1,SPR,EFNB1,LGALS3BP,HLA-A,COX7A2,WWP2,MGAT1,FUT8,CD9,SGK3,SLC44A2,TAGLN2,PDGFC,SHMT1,B3GNT2,CASK,ALDH2,ERMAP,DENND1B,VAMP3,FURIN,PARP4,C1GALT1C1,UBAC1,YES1,AIF1L,GPLD1,CRTC2,NUCB1,TIMP3,CTNS,ACADSB,FGFR2,PRDX3,RIN3,ABCB1,ERAP1,SERPINB5,GPER1,FZD5,ARSB,OCLN,RGMA,ST13,CRYM,HEBP1,MPP5,TAF6L,ERP29,MAP1LC3B,ECI1,SH3KBP1,EPCAM,RAB15,METTL7A,TSPAN6,DPYSL2,CAPG,DLG1,AKR1B1,RAB20,RP2,MYH14,CTTN,MYRIP,LAMP3,NLRP4,SOD1,ASXL1,LAP3,ITCH,ARHGDIB,TCN2,SEC14L2,CXXC4,ZNF114,GPRC5B,KCNK1,UEVLD,CAB39,GLA,NRGN,APBA2,CPPED1,CAPN1,PCSK5,GRN,LASP1,FAM213B,PIFO,SERPINE2,ASL,ATP6V1E2,CALM3,PM20D2,SPP1,CA2,PFKL,FAM20C,OCRL,COL6A1,PRKCI,HLA-C,SLC12A2,GAD1,SNED1,CCDC88A,SNX7,KDELR1,VWA1,NUBP1,C3orf58,EGFR,MUM1L1,GNAS,INSR,PLPP3,TMEM30A,SH3BP4,RAB31,CTSA,PITPNA,KIF12,SHROOM2,PROM2,PSME2,SLC2A8,HDAC11,SOD2,COL18A1,MRAS,SAYSD1,PHLDA1,EXT2,SMO,GOT1,ECE1,PDIA6,LOXL1,HSPA2,CHP1,EBAG9,GCA,IGSF8,GLO1,CD40,BHLHB9,SECTM1,CANT1,SPTBN5,LIFR,ABCA1,ANXA3,SORT1,ENO2,TSPAN15,SERPINB9,ITGA2B,TMEM63A,KIF5B,MLPH,TAF1B,A4GALT,BMP7,GALNS,ZDHHC13,ACTA2,H2AFY,HSPA13,MYO5A,SYPL1,PGM1,RAB3B,SYBU,NDRG3,ENDOD1,CTSL,HLA-B,GAREM2,RND3,DHRS2,PRCP,CTSV,RAP2C,UBE2D2,UACA,ARRB1,GLB1,ATP6V1C1,PLOD3,LRRC57,CD33 |
| 8.708e-17 | -36.98 | ELAVL1 (ELAV like RNA binding protein 1) | protein interactions | 1994 | 1762 | 405 | 16036 | 2547 |
LAMP1,ACACB,HECA,SSH1,FAM160B1,TSC22D3,SLC25A13,TMEM41B,XIAP,CUL1,FAM102B,C1orf198,PJA2,DPP8,SLC20A1,BARD1,FAM46C,SPSB1,CMTM6,PHF1,NCS1,NAPG,SESN3,TGFBR3,CTGF,OSBPL3,ALDH1A3,SNX16,MARCH2,ZBTB18,LAMP2,TMEM68,SNTB2,SERTAD4,TFAP2C,SAV1,ICMT,SLC25A5,RAB2B,ARF4,SGPP1,SFXN1,KDSR,ANKRD10,PIAS3,RBM47,LIMK1,ATP7B,EIF4EBP2,TRAF5,NXT2,FGD1,KLF2,NUAK1,PRKAA1,C6orf106,ARHGEF35,TTYH3,MECOM,CALR,TFAP4,WDFY1,ZNRF2,SLC16A6,FAM13B,RANBP1,CD70,OSTF1,FAM84B,C9orf72,TMED2,PAQR7,TRAK2,GID8,GFPT1,MMD,PRSS23,SALL4,LPGAT1,MICB,ANO6,CALM1,AMER1,PIP4K2C,VEZT,KIF20B,SRSF5,ELK1,ANTXR1,NFIB,GNA11,RHOB,DCP2,AP1AR,NCOA3,SERTAD2,PRKAG2,MTFMT,SEMA4D,DCK,SETD3,NR4A2,MAL2,TMEM159,FBXO27,ELK4,SPRED1,TCTN2,SUZ12,CAST,C5orf30,BLCAP,RNF182,IL13RA1,TMEM19,CCND1,APLP2,FAM46A,DOK4,CDKN1B,TNPO2,EPHB4,ACSL4,DLG3,SNX10,SZRD1,ERMP1,FOXJ2,PANK1,VPS4B,NUSAP1,ATP1B1,H2AFV,GIGYF1,ZMPSTE24,NIN,IRS2,OSBPL2,SPIN3,CFAP45,STK26,AXL,CORO1C,SLC9A6,INPP4B,TRIOBP,PPP1CB,EFCAB14,KLF5,PDXK,ISOC1,ARNT,PRKAR1A,FARP1,DEPDC1,MPZL1,SLC41A1,TRAF2,SDC4,OSGIN2,EFHD2,GPR180,FAM217B,GMCL1,SLC25A43,ETS1,PDIA4,NEO1,SGPL1,SCML1,CTNNBIP1,AKIRIN1,DTX3L,CXCL16,SLC27A6,GNB5,PTEN,FAM20B,CD9,AK3,CITED2,CASD1,SPRY2,SLC16A5,TMX1,HCN3,TGIF1,CASK,PAPD7,BCL9,FURIN,AK4,YES1,LRRC1,AIF1L,SKA1,KIF11,SEC14L4,CCDC6,AMMECR1,RYK,ARSB,SHOX2,WDR45B,FOXA1,SRSF9,JARID2,PHC1,EXPH5,CCNI,CASP3,FAF2,TRIM2,ST13,EPAS1,FAM199X,CNOT8,FLYWCH2,CUL4B,DNAJB11,F11R,HDAC6,NUP62CL,SH3KBP1,CTNNB1,CASC4,METTL7A,DPYSL2,SLC44A1,MITF,TRPC1,CTTN,SLC39A10,BTBD3,TRAM1,FGFR1OP2,STK35,ING1,TRIM8,FOPNL,ACBD3,STAU2,ITCH,CBX6,EZR,ERP44,IDH1,VCP,TRAM2,PI4K2B,CDCA4,KCNK1,DOLPP1,TRIM45,ADIPOR1,KLF11,PXDC1,CHPT1,TC2N,STARD3NL,PARP12,PPP1R12A,SERPINE2,PPP1R2,ZNF395,LRRFIP2,UBASH3B,ETV5,PDCL,CALM3,PM20D2,RAB6A,PHLPP1,DHRS3,DUSP5,SSX2IP,MYO5C,DAZAP1,KIAA0895,UBE2Q2,GATA2,SPIN4,OCRL,PAK2,PRKCI,EXOC8,LIMCH1,PIM1,DESI2,CKAP4,CYP26B1,STRADB,FBXO8,PRRC1,ZDHHC3,GLCE,MAPKAPK2,FECH,UAP1,ZC2HC1A,TMEM30A,OTUD6B,PAPD5,PRPS2,RAB31,YOD1,AKIP1,TMEM14A,IFI6,TOB1,CTBP1,LZTFL1,CTDSPL,TP53,OSR2,SAYSD1,PHLDA1,PCBP1,KCTD9,PER2,SS18,EFR3A,WDR44,REEP1,EPB41L4B,APIP,LMAN1,DVL2,GM2A,CTH,SEPHS1,CHP1,FRS3,CPD,SIRT1,GCA,BAG4,OSTM1,COQ10B,C3orf52,FANCE,DAG1,C3orf33,SOCS3,TAPBP,PTGS2,PTBP3,VSIG10,SGOL1,LTA4H,CNEP1R1,TMEM263,BIN1,MFSD14B,GOLIM4,SORT1,ARHGEF11,CIT,SH3D19,GNE,CDCA8,AES,COL4A5,TGFBR1,VPS26A,FZD6,XPR1,DNAJB9,CCDC92,IRF2BPL,CARD8,TFAP2A,UBE2J1,SGK1,ABCD1,MTURN,TSPAN13,KLF9,IQGAP3,C12orf75,FAM134C,HES1,MLEC,MOSPD2,NR3C1,GCLC,PLAUR,AMFR,RC3H2,LITAF,NADK2,FNDC3A,TCEAL8,NDRG3,BCL10,DDAH1,ZMYND19,CDCA7L,RAP2C,NETO2,SLC18B1,GUCD1,UBE2C,ZBTB33,ABCG1 |
| 1.227e-16 | -36.64 | carcinoid-endocrine_tumour | COSMIC cancer mutations | carcinoid-endocrine_tumour | 8129 | 1375 | 17775 | 2585 |
FAM160B1,IBTK,AK7,SLC25A13,HEXB,RET,CCNO,TRAPPC8,LACTB2,SNX9,SPSB1,LTBP3,CDKN2C,NAPG,PAQR5,DNM2,TIAM1,CPE,MGAT5,NEK4,DSTN,TMEM151A,TFAP2C,PRKAR2B,PNKD,ABR,LCP1,ENPP1,C17orf51,ATP7B,CELF5,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,STARD13,HSPB1,ANXA11,ZNF720,MTL5,TTYH3,ATG4A,MARCH8,RAC2,ZCCHC17,FRY,RIMS3,MAP3K9,SLAIN2,CADPS2,ALPK1,CNGA1,MAPK7,MOXD1,DGKG,NUP85,PHKG2,TTLL1,MCCC2,HPS3,PQLC3,FHL2,ELK1,SFXN5,GNA11,PSMA4,CACHD1,FNTA,SLC4A4,S100A5,DGAT2,CLMN,OSCP1,GDF11,TMEM159,CBX5,ADAMTS16,DMPK,DOCK9,WDR63,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,KIAA1147,APPBP2,MUC16,ST5,CDH1,SH3BP1,XYLT2,DLG3,MYT1,SNX10,TMCC2,MX1,SNX8,SEC61B,COL6A2,ERMP1,RIPK2,PFKFB2,AGPS,PTPN9,SEPT6,VPS4B,XRCC6BP1,TANC1,EBF2,GIGYF1,GABARAPL1,PDLIM3,CCNB3,SHROOM3,CDK19,CORO1C,AXL,FAM149A,PRIMA1,MAPK12,MZT1,MPZL1,FAM189A2,BACE1,HABP4,CCM2,SDC4,FLOT1,PLPPR4,IFT27,SLC25A43,ZFX,PDCD10,ITGB8,KNDC1,TMEM62,TUBGCP6,FAM20B,KLC3,FAM102A,IGFBP2,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,CXorf57,AK4,PGBD1,RAB3IP,C4orf27,PROM1,LDLRAP1,PLOD2,RAB11FIP2,SYT7,FAM3C,PLA2G15,PPM1H,ACOT7,PHC1,TLL2,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,TEX2,F11R,GALM,ITPR2,SPTB,PLS3,CPNE2,INPP5E,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,NPNT,IL6ST,PAPSS1,SLC44A1,TMEM143,NTN4,SMAGP,PLK1,THRB,PTPN18,MARK1,KCNIP3,CELSR2,CBX6,CR2,EAF2,DZIP1L,TRIM9,TNS4,PLEKHG6,PI4K2B,HS6ST1,TRAM2,KCNMB4,AGPAT2,KLF12,ZNF367,KLF11,KPNA2,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,USH1C,SORBS3,ADCK5,RAB6A,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,FRAS1,ICAM5,FCHO1,SLC30A6,PIM1,FAR2,WNT3A,NTN1,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZNF320,STRADB,ZSCAN12,PDK3,BCL2L13,NMT2,C18orf8,KBTBD2,PHLPP2,P4HA3,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,RHPN2,P2RX7,BAHD1,STIL,TTC21B,WDR44,TACC2,LMO4,PPME1,PLK4,CDH3,GLB1L2,ESPN,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,DAG1,ATP13A2,IDE,PTPRJ,PAFAH1B3,RBL1,ABHD12,STK38,MAOA,XRCC3,CHMP4B,EFNA5,SYT13,FAM134B,BIN1,CMAS,PINK1,DYRK3,CDH22,CPEB4,CTSB,SCD5,GNAL,MCTP2,HAL,ERCC6L,ERI2,NRP2,SH2D4A,CD109,C16orf74,CDK16,LYPD6,GTF2F2,IL17RA,SGK1,TSPAN13,ALDH7A1,HMGCL,SYK,FAM134C,ATP2B1,NFE2L3,FBLN5,MOSPD2,CRIP2,DPP9,MAML2,GGH,COL7A1,BBS2,DDX23,CNOT2,DDAH1,FGF18,E2F1,ICOSLG,PTGES,HIPK3,ARHGEF4,GOLGB1,FAM171B,LAMP1,SLC35D2,PNISR,LGR4,HSPG2,SSH1,VANGL1,C1orf198,CUL1,PDGFRL,CAMK1D,NANS,SEPT4,VASH1,PICK1,SLC9A7,PAK6,TYMP,ANKS6,ZNF823,STIM1,OSBPL3,PIK3CA,SNX16,SGCE,SPATA18,ACVR1C,CDYL,LDB2,SH2D3C,LRIG1,PRDM5,MAPK13,SERPINI1,F2RL1,CCDC97,FGD1,RECQL,MRC2,TBC1D1,TMEM55B,PRKAA1,APBA1,TNFRSF19,S100A2,PDXDC1,PSIP1,SH3RF2,C9orf69,CALR,DOPEY2,RALGPS2,LYPD3,ZNRF2,MSH2,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,OSTF1,CACNA1D,KCTD3,SYTL3,GPR161,SPATA20,GCC2,PRODH,KCNJ12,KLK5,CEP89,ADCK3,LPGAT1,PYGL,WHSC1,ANTXR1,NFIB,PDE11A,MMP15,NT5C2,AP1AR,SLCO4A1,PLEKHH2,TJP3,PELI2,C1orf21,MPP2,FAM83D,APPL2,AGBL5,SFMBT1,CABIN1,SAMD8,CDK18,KLK7,ZBTB34,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,THRA,NDRG1,RALBP1,ATP2C2,FAM78A,BCL2L1,TMEM170B,FLT3,DDR1,CYP39A1,ZFYVE9,EPS8L2,EPM2A,NOV,CCNA2,ACAP2,EPHB4,RNASEH2A,FLOT2,MED30,ATG4D,CLSTN1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ITPR3,ALCAM,ATP10D,DDOST,TSPAN18,ZNF704,COBL,CBX7,MAMDC2,PLSCR4,CENPI,EPS8,CBLL1,HERC5,PBX3,FBXO6,DNAH3,WWP2,CKAP5,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,ERBB3,SLC16A5,FARP2,TGIF1,PDGFC,ARHGEF28,ZC3H11A,TMEM221,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,KIF11,CDK5RAP1,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR91,CXorf56,DEF6,MELK,RGMA,FAF2,UGT8,CRYM,PLAC1,MPP5,MAP1LC3B,ECI1,ADPRHL1,ZFYVE16,SIPA1L2,CASC4,CDKL5,ARHGEF37,SIVA1,ANKFN1,TRPC1,ASH2L,MYRIP,STK35,LAMP3,ASXL1,ITCH,ACBD3,RGAG1,MAN2A2,HPSE,KCNK1,MADD,TDRD7,RBM43,NRGN,CHPT1,CAPN1,NR2C2,PCSK5,LASP1,ZNF395,PPP1R12A,BVES,ETV5,ABCG2,CALM3,FAM81A,ADAMTSL4,QSOX2,TYW3,CES2,FAM20C,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,NPTN,ZRANB1,ETV7,SLC12A2,MDFI,ELK3,PODXL2,PDE5A,KIAA1109,PRRC1,HEATR5A,NUBP1,PDIK1L,RANBP9,SOX13,INSR,UAP1,TMEM30A,DCUN1D1,SH3BP4,RAB31,SHROOM2,JAK3,COL16A1,APOL2,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,MXD1,CYP4F11,REEP1,ZBTB49,DIXDC1,EPB41L4B,ECE1,ETHE1,NFKB2,UPF3A,SEPHS1,RFK,PTPRU,GLO1,TMTC2,CDC25C,PDHX,CASP4,ALDH5A1,STAT6,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,KDELC2,GLIS3,GCLM,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,RBP7,XPR1,TMEM63A,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,ACTA2,H2AFY,SLC35A1,MYO5A,RBMS2,B3GALT6,PGM1,WNT10B,RC3H2,TTC7A,RUNX3,NDRG3,LEMD2,ENDOD1,CASP7,SWAP70,TRIM69,FIBCD1,SPINT2,CSGALNACT1,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,ACACB,TRIM24,ADD1,IL15RA,AASS,DNAJC3,CACNA2D2,SMARCAL1,DHX8,NRG2,IL18,SYTL4,CA8,BARD1,KIF26A,PHF1,CALM2,DAPK2,TP73,WEE1,TGFBR3,RGS12,AP1M2,ARHGAP42,KIAA1107,DNAH6,CYP2S1,CABP1,SLC46A1,RDH14,KLF3,ALDH1A3,FUT1,PIK3CD,ODF2L,ERAP2,TUBA4A,NWD1,SMARCA2,TNIP1,SERTAD4,SH3BGRL,RNF11,LOXL2,F12,ICMT,PPP1R14C,MYOM1,CYP4F3,COL12A1,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,MRPS28,RELL1,PDPR,GAB1,TMTC3,CYP2J2,SLC36A4,MERTK,LMNA,RAVER2,GNS,WDFY1,FAM189A1,CD22,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,SLC37A1,SALL4,STAT4,MYBL2,CALCRL,SPTLC2,DCP2,STK17A,DHX32,PTPRF,NAAA,SCARB2,MTFMT,SEMA4D,HTT,SETD3,DYSF,AURKA,OSMR,FBXO27,ARPC2,DRP2,NDE1,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,WDTC1,TESK2,PKP2,IL13RA1,PRKACA,ZNF385B,UHRF1BP1L,CDS1,CCND1,RNF220,RTKN2,RAB27B,TMEM9,SCN3A,RNF169,LGALS8,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,TTC12,WWTR1,SIPA1L1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,TAOK2,TNRC6C,MAN1A2,PDIA3,GMCL1,ANO9,PKN1,KCNC4,TSPAN17,PDIA4,NEO1,CAPN2,ANK1,ADD3,SLC27A6,IRAK1,FAM160A2,ARSG,CTSC,ANKS1B,KCNK5,CALD1,ADAM15,MAPK11,WWP1,SGCB,CRTAP,POU6F1,AMOTL2,LCA5,FMN1,FAM160A1,CTNNAL1,RAPGEF2,EIF5A2,GRIN1,PLEKHA7,DBR1,BLVRA,NEURL1B,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,BTG1,ACVRL1,CCDC6,ARFGAP3,NUP37,USF2,CYBRD1,DCBLD1,MYL9,AGRN,GNPDA1,FAM199X,PPM1J,EPHA4,MCCC1,NUP62CL,SDC1,PIGL,SHC3,DDHD2,DUSP10,RGS5,ANO4,TLN2,PXMP4,TRAM1,NEB,DDX59,CCDC38,ZNF462,MCTP1,EZR,ERP44,KLK6,ANLN,IDH1,CLCN2,RHEB,OPTN,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,PIK3C2B,PIEZO1,EPB41L4A,POMT1,GLCCI1,PRKAA2,UBASH3B,RACGAP1,CNTNAP2,DOCK11,IL18R1,PGAP1,RB1,VASP,DAZAP1,KIAA0895,IGF1R,MDFIC,TMEM8A,PLCB2,ALDH3A2,CHSY3,CYP26B1,WDR72,TESK1,TCF7,EIF2AK1,UNC45B,ANKRD29,G2E3,MAPKAPK2,PRPS2,LTBP2,ATP1B3,CTBP1,FAM45A,NF2,UGP2,FOXM1,XYLT1,DGKA,CCDC68,ERBB2,CCNL1,LPIN3,PER2,CDK14,RAD23A,SRPX,EFR3A,GYS1,MINPP1,SCN2A,FAR1,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,TCEB2,COQ10B,MYL12A,DUOX1,DNAJC10,RTN4RL1,PTK7,ADAMTS14,ANXA9,NDST3,ZC3HC1,CMTM4,GOLIM4,TRAPPC10,RUSC2,DAP,GABRG2,PSMD10,JAG2,DSE,CRABP2,SIRPA,PPP2R3A,SLC9A2,CEP97,ABCD1,BUB1,CAMK2G,FAH,DLGAP1,NR3C1,AMFR,CAPNS1,FXR2,PELI3,FNDC3A,MAPK8IP1,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,CDCA7L,NETO2,PGRMC1,FAM117A,CLIP4,PPP2R3C,PKD2,TBC1D4,NDFIP1,GAA,ACVR1,PPP4R4,TMEM41B,FAM129B,ATP8A1,KLC2,PPFIBP2,GATA3,PLXNA1,PLA2G16,ELMOD2,NCS1,SESN3,ELMO2,ZFP36,IQCE,IL31RA,AOX1,ATRNL1,IQCD,LOC81691,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,TNS1,AURKB,GALNT7,SLC17A5,CCNF,SAV1,SLC25A5,ZFAND5,ULK2,ARHGEF26,SGPP1,AHRR,SFXN1,KDSR,SLC25A4,PLK2,PTER,GNPTAB,TBX1,NKD1,UNC5B,TANC2,RTN3,DDX58,CDK17,INPPL1,FRMD4A,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,NOTCH2,SLC1A3,BMP2K,ITGA3,PIK3AP1,NECAB3,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,TMED2,FAM69A,DNAI1,EPB41L5,PMPCB,DDB2,QSOX1,KIAA1841,MFI2,TBC1D8B,PTPRH,PIP4K2C,KCTD20,STX3,RASA1,FRMD4B,DGKH,PRKAG2,ISM1,DCK,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PKD1L2,FRMPD3,PLA2G4A,CEP70,SUZ12,IQGAP1,RPS6KA1,AIFM2,TMPRSS4,SLC25A35,APLP2,ZNF75D,FAM46A,CNNM4,PHKA2,GPX4,MYO5B,SEC23A,SLC5A11,CAPN6,TMEM43,TEP1,PRKCQ,AKR1E2,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,OSBPL2,EPHA10,ZNF641,FYN,JAK1,PPP2R5A,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,HS3ST3B1,MLKL,NR3C2,DENND5B,MRPS9,WASF3,PCOLCE,ATP9A,CCNJL,GPR180,SPR,SIX4,TMCC3,FAM111A,OXCT1,PTEN,SGK3,ATP8B1,SLC44A2,MAP3K7,NCOA2,PCCB,ARAP2,SHMT1,CASK,ERMAP,MPP1,DENND1B,VAMP3,FURIN,PARP4,LRRC1,RGS9,NUCB1,RCBTB2,PRDX3,SLC25A40,AMMECR1,PGM2L1,GRIN2D,ARSB,OCLN,JARID2,ESYT2,EXPH5,LTBP1,ST13,CAMKK1,HEBP1,EPHX4,TAF6L,DNER,CACNB4,TMC1,SH3KBP1,PTCHD4,ABCD4,NKAIN3,ARHGEF10L,LRRC6,IMPAD1,DPYSL2,PHTF1,CAPG,DLG1,AKR1B1,POF1B,SUN3,RAB20,RP2,NFU1,MYH14,ARNT2,SLC39A10,TECR,PTPRE,RASGRP1,OLFML2A,TDP1,ATL1,TRIM8,SYNE3,FOPNL,RNF165,ROR1,MRPS18A,PTGFRN,ADRBK2,STK17B,TCN2,EDNRA,CXXC4,ARHGEF19,FASTKD1,DHRS13,IARS2,TRIM45,CCDC74B,ADIPOR1,APBA2,PSMC1,PPP2R5D,CPPED1,LRRFIP2,ELOVL7,SAMD9,PHLPP1,ZNF432,AIM1L,EBF4,FNIP1,FXYD5,KNTC1,LRIF1,ALS2CL,FBXO8,AMDHD1,EGFR,MUM1L1,GNAS,XKRX,FECH,BCAR3,TSC1,SLC6A6,UTP14C,ALPK3,PITPNA,KLF7,ZSWIM5,FAM92A1,SPC25,SLC2A8,GMPR,TDRKH,ZMYND10,PATL2,MICALL2,LRRC45,SLC25A48,SS18,ZDHHC12,FRYL,RPN2,F2R,LOXL1,SCYL3,MAP3K3,BAG4,KREMEN2,SLC39A8,ERBB2IP,DOCK5,MAP3K6,BFSP1,OVOL1,VSIG10,PLXND1,AKNA,PPP2R2D,LIFR,ANXA3,POC1B,FRMD6,ARMC7,LRP4,TRMT2B,ZNF212,IL17RB,SNX13,ADORA1,GALNS,KIAA0319,BRD7,TRIM3,IQGAP3,SYPL1,ADAM17,RAB3B,ASPM,DEPDC4,PHLDB3,NR4A1,MBNL3,LRRC66,OGDHL,MAP1B,KLHL2,PRCP,UBE2D2,OTUB2,HOXB13,LRRC57 |
| 1.470e-16 | -36.46 | membrane-bounded organelle | cellular component | GO:0043227 | 11730 | 1900 | 17570 | 2579 |
HECA,IBTK,SLC25A13,PNPLA2,HEXB,RET,CCNO,TRAPPC8,TGOLN2,ISOC2,LACTB2,DPP8,SNX9,CMTM6,LTBP3,GRM5,ZNF275,NPM2,CDKN2C,NAPG,MUC4,UBE2T,ATP13A3,DNM2,CRY2,PPP1CA,WBP4,IL10RB,TIPARP,CPE,MGAT5,DSTN,UXT,TMEM98,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,GINS4,LCP1,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,CELF5,ATP7B,NOD2,HDAC1,RNASEL,HSPB1,STARD13,ANXA11,NXT2,SCN5A,GGA1,SEC61G,MTL5,RAB23,COX6C,FAM21C,TTYH3,MARCH8,TFAP4,FLII,RAC2,SH3D21,ZCCHC17,ATP5H,MEGF8,FLRT3,FBXO7,RANBP1,FBXL14,PCYOX1,CADPS2,USP1,MYDGF,CNGA1,ZMYM1,MAPK7,MOXD1,NUP85,PPP6R1,MCCC2,REC8,PQLC3,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,GOLT1A,PSMA4,GNA11,SFXN5,PLIN5,IL1R1,SLC4A4,ETS2,APMAP,S100A5,DGAT2,STK39,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,DMPK,NQO1,LFNG,CD82,APOO,PTTG1,MAPK4,MGST2,MVB12B,MOCS1,APPBP2,RCN1,RBM23,MUC16,CDH1,XYLT2,TAX1BP3,MYT1,SNX10,ETV4,MX1,SNX8,SEC61B,ERMP1,COL6A2,AGPS,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,GTF2A2,SNX12,TRIM7,ZNF618,COX20,EBF2,GABARAPL1,NFIX,ALDH3B1,CCNB3,CDK19,WFS1,AXL,PNPLA6,SLC25A30,ISOC1,MAPK12,HSP90B1,GCAT,BACE1,TRAF2,DCAF7,ESRP1,BIK,SDC4,HABP4,FLOT1,CTSZ,ZNF219,HDGFRP2,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,GPC3,MGAT4A,FAM20B,CST3,TUBGCP6,BAX,IGFBP2,RAG1,MED22,PARP9,ACBD5,PVRL4,PLSCR1,TACC1,PIK3R1,DUSP23,MRS2,NUB1,UBE2A,PGBD1,AK4,RAB3IP,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,FAM3C,PLA2G15,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,WDR45B,SRSF9,ACOT7,PHC1,BCAM,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,NDRG2,F11R,NENF,ITPR2,GALM,MGAT5B,SLC9A3R2,FANCI,TFAP2E,SUSD2,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,P4HB,IL6ST,ARL1,PSMC2,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KCNIP3,PTPN18,STAU2,CBX6,NFE2L1,CR2,CCBL2,ARFRP1,EAF2,SESN1,KDM4D,TRIM9,HS6ST1,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,KPNA2,TC2N,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,PSMD7,SORBS3,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TIMP1,RINL,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,USP31,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,PRX,NMT2,C18orf8,CDK5R1,FOXD2,FA2H,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,AKIP1,CDAN1,CCNB2,USP43,RAD21,HOXB7,CTDSPL,TP53,P2RX7,RHPN2,BAHD1,PCBP1,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,KMT5C,WDR44,TACC2,BCL6,PLK4,ZDHHC23,VAT1,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,PTGS2,TAPBP,ZNF628,PTPRJ,IDE,PAFAH1B3,RBL1,STK38,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ST3GAL1,FAM134B,ARFGEF3,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CPEB4,TAB3,CTSB,SCD5,GNAL,MCTP2,CDCA8,ERCC6L,ERI2,GTF3A,GDF15,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,HMGCL,SYK,ATP2B1,GCNT1,WBP5,DUSP1,NFE2L3,P2RX4,HES1,FBLN5,RHOA,HMGN5,GUSB,PLAUR,PRICKLE1,DPP9,STMN3,MAML2,GGH,COL7A1,TXNDC11,RNPEP,BBS2,USP6,BCL10,DDX23,CNOT2,DDAH1,SCG2,NEIL3,NIPSNAP3A,FGF18,E2F1,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,PKIA,GOLGB1,LAMP1,SLC35D2,TXN,PNISR,SSH1,HSPG2,TSC22D3,CUL1,PSME1,NANS,CAMK1D,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,PAK6,HELZ2,CYP1A1,ZNF823,STIM1,OSBPL3,PALD1,FOSB,POLL,KCNS3,SERINC2,IRF2,SNX16,HYLS1,TACSTD2,MARCH2,ZBTB18,SGCE,SPATA18,CDYL,BNIP3L,SLC35C1,KIF13A,LDB2,POR,RAB2B,PRIM1,PPP2R4,PRDM5,BMP1,SERPINI1,NFKBIZ,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,PRKAA1,AKAP17A,TXNDC9,HERC6,APBA1,PDXDC1,PSIP1,SH3RF2,MESDC2,C9orf69,CALR,DOPEY2,ZNRF2,BHLHE41,VASN,MSH2,TPST1,PRKG1,OSTF1,CYSRT1,DLX4,ZNF117,SYTL3,GPR161,TRAK2,PIGC,GID8,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,CALM1,WHSC1,PYGL,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,TJP3,FAM64A,FAAH,WDR19,ZDHHC20,AGBL5,PIAS2,APPL2,ARAP1,SFMBT1,CABIN1,KLK7,SAMD8,ZBTB34,PLIN3,PER3,IFIH1,EHD1,FOXO6,SPRED1,TCF25,DLGAP5,TCTN2,GPR107,ST14,THRA,CERCAM,NDRG1,CCDC110,ATP2C2,FTH1,BCL2L1,FLT3,DDR1,CYP39A1,ZFYVE9,EPS8L2,EPM2A,APOBEC3B,CD46,NOV,CCNA2,ACAP2,RALB,RNASEH2A,PDE4D,EPHB4,OSBPL7,TSPAN1,SULT2B1,FLOT2,NAGA,MED30,SEMA3B,ATG4D,MSANTD4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,CLSTN1,KIF1C,ATP1B1,RAD17,PYGO1,PKMYT1,CBL,B3GALNT2,ITPR3,ALCAM,TRIQK,ATP10D,CEP162,ZMPSTE24,DDOST,ACAD10,NGFRAP1,TRIOBP,SLC27A3,CBX7,MAMDC2,PLSCR4,IGFBP6,DEPDC1,CENPI,EPS8,CBLL1,PBX3,PLD2,FBXO6,SPDL1,EFNB1,COX7A2,HLA-A,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,RNF128,GNB5,FUT8,DRAM1,CD9,CITED2,TTPA,MSH6,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,PAPD7,ZC3H11A,TCFL5,ZKSCAN2,DIAPH2,UBAC1,YES1,AIF1L,FOS,ARSK,CPTP,CRTC2,TIMP3,ACADSB,FGFR2,TBX18,RIN3,ABCB1,RYK,ERAP1,RABL6,LRRK1,WDR62,FZD5,ESPL1,DEF6,RGMA,CCNC,FAF2,UGT8,CRYM,UBE2Q1,VARS2,MPP5,COMMD5,MAP1LC3B,ERP29,SLC8B1,ECI1,TRIM68,EPCAM,ZFYVE16,RAB15,HSF2,CASC4,METTL7A,CDKL5,SIVA1,ASH2L,CTTN,MYRIP,BTBD3,STK35,SP5,LAMP3,CERS2,CYP1B1,NLRP4,CXXC5,CENPA,ASXL1,LAP3,ITCH,ACBD3,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,TDRD7,SH3GLB2,CAB39,ZNF165,SP6,GLA,CHPT1,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ZNF395,SERPINE2,PPP1R12A,ETV5,ASB9,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,SPP1,CES2,FAM20C,PFKL,OCRL,COL6A1,SUCO,PRKCI,SRP54,BRAT1,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNED1,MDFI,SNX7,ELK3,VWA1,KIAA1109,PRRC1,NUBP1,PDIK1L,C3orf58,STEAP1,RANBP9,SOX13,INSR,UAP1,TMEM30A,SH3BP4,SPAG7,RAB31,DCUN1D1,CTSA,DONSON,SHROOM2,TOB1,APOL2,COL16A1,RARG,SNX30,DRD1,LMO7,CCNE2,SORBS1,PAX6,FAM214B,HDAC11,SOD2,PDIA5,COL18A1,MRAS,OSR2,SAYSD1,PHLDA1,EXT2,MXD1,SAP130,ZNF687,CYP4F11,COX14,KIF14,REEP1,ZBTB49,ECE1,NFKB2,ETHE1,UPF3A,EBAG9,CHP1,SEPHS1,SOAT1,RFK,C3orf52,MRPS35,GLO1,TMTC2,CD40,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,HSF4,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,PTBP3,SPTBN5,MAD2L1BP,ABCA1,KDELC2,GLIS3,ENO2,TSPAN15,CIT,SHPRH,SH3D19,ARHGEF7,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ZDHHC13,ACTA2,ARVCF,H2AFY,KANK2,RPGR,SLC35A1,RBMS2,MYO5A,B3GALT6,PGM1,DCAF6,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,NDRG3,TCEAL8,FOXL1,ENDOD1,LEMD2,CTSL,CASP7,SWAP70,RND3,TRIM69,CTSV,RAP2C,CSGALNACT1,UACA,ARRB1,MCUR1,ZMIZ1,PLOD3,AHR,CD33,ABCG1,DOC2A,ACACB,KLK10,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,SMARCAL1,MMADHC,FBXO2,XIAP,DHX8,LGI3,LYNX1,IL18,MORF4L2,SYTL4,BARD1,PHF1,EPDR1,TP73,CALM2,DAPK2,WEE1,ZYX,PQLC2,PSMD1,AP1M2,TGFBR3,RGS12,CABP1,CYP2S1,ALDH1A3,RDH14,KLF3,FUT1,TUBG1,SEMA3G,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,TUBA4A,SPEF2,VPS11,SMARCA2,TNIP1,SERTAD4,SH3BGRL,SPRTN,RNF11,MTRF1L,LOXL2,F12,ICMT,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,SERPINB6,MRPS28,ARF6,E2F8,PDPR,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,CYP2J2,SOX9,SLC36A4,LMNA,ELF3,RAVER2,GNS,DNPEP,WDFY1,CD22,PRICKLE4,ZIC5,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,NAGPA,UFD1L,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,ILK,MEST,TP53INP2,SPTLC2,RHOB,DCP2,CYB5A,STK17A,DHX32,PTPRF,NAAA,NCOA3,SCARB2,MTFMT,TIMM8A,HTT,SETD3,TEX30,ITPR1,AURKA,DYSF,MDH1,ALG2,B4GAT1,MAL2,ARPC2,ZNF502,SERPINB1,RPS6KA3,CSRP2,XDH,EGLN1,MTM1,CCDC109B,GRHL2,TUBB4B,GALNT12,ACTR8,ETNK1,RGS20,WDTC1,TESK2,PKP2,NUF2,PRKACA,APC2,KTN1,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,RNF169,ENPP4,SSH3,LGALS8,NRBF2,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,PXYLP1,RAB38,PEX5,STX10,SLC9A6,WWTR1,TRABD2A,PDXK,RGS14,GEN1,ARNT,TTC8,GALK1,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,PDIA3,GMCL1,PKN1,TMA16,NUCB2,ETS1,GSTP1,HOXB2,TIPRL,ICAM1,NEO1,PDIA4,DTX3L,CAPN2,ANK1,ADD3,IRAK1,CTSC,ARSG,ANKS1B,ALG13,FDXR,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,ZNF230,MAPK11,AK3,ITM2C,TPCN1,S100A6,TMX1,CRTAP,POU6F1,MOB4,AMOTL2,NUDT8,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,PLEKHA7,DBR1,BLVRA,NEURL1B,FAM109A,CRISPLD2,TXK,GALNT3,PITX2,BTG1,KIAA0141,ATXN7L3,NR1D2,ZFP30,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,CYBRD1,FOXA1,UNKL,UNC93B1,AGRN,GNPDA1,CUL4B,EPHA4,SUDS3,MCCC1,NDC80,CDIPT,HDAC6,PDGFB,NUP62CL,SDC1,PIGL,PCNA,LMAN2L,DDHD2,ELF5,DUSP10,PXMP4,TRAM1,MYBL1,DDX59,NEB,S100A13,ZNF462,PCGF5,CD55,ING1,HN1L,CITED4,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,RHEB,OPTN,IRX3,DPYSL3,PLCH1,MFAP3L,TBC1D17,CDCA4,MSL1,MAP2,WIPI1,P4HA2,DOLPP1,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,POMT1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DHRS3,PGAP1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,GATA2,CMTR2,PAK2,EXOC8,MDFIC,TMEM8A,ALDH3A2,PSMA5,ABCC1,C9orf9,CYP26B1,CHSY3,MRPS33,PCBP3,SPATA13,KBTBD8,TCF7,IFIT3,ZDHHC3,G2E3,SMN1,MAPKAPK2,EPN3,MOSPD3,COQ10A,H1F0,PVRL2,CSF1,MFSD2A,PRPS2,LTBP2,ATP1B3,TMEM120A,CTBP1,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,ERBB2,CCNL1,FAM198B,LPIN3,CYP26A1,C1orf116,SDF4,PER2,CDK14,RAD23A,ATP6V0B,SRPX,EFR3A,LHX6,PLCG2,N4BP3,MINPP1,EGLN3,FAR1,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,TIMP2,MBP,EVA1A,TCEB2,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,MYPOP,DNAJC10,RTN4RL1,ATP1A1,PSMD3,ANXA9,ZBTB6,RPL22,AIFM3,LTA4H,CNEP1R1,ZNF701,NDST3,POMGNT2,COPG1,ZC3HC1,MAN2B2,GSDMD,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,CD63,ADGRG1,RUSC2,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,SIRPA,GBX2,MAGEE1,SLC35B4,BUB1,ABCD1,KLF9,HEXIM2,CAMK2G,TLE6,FAH,MLEC,PSMB4,IFITM3,NR3C1,CRB3,AMFR,LITAF,PPARA,CAPNS1,CARD19,TRIM35,FXR2,AKAP3,FNDC3A,BCAR1,MAPK8IP1,SCRN2,PRDX4,FUCA1,TMEM50B,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,TMC5,NMI,PGRMC1,PPP2R3C,PKD2,SPCS3,ACADM,NDFIP1,TBC1D4,UBE2C,SAT2,DIS3L,SUN1,GAA,FAM129B,ATP8A1,TAP1,GATA3,PLXNA1,CCNB1,PLA2G16,RIC1,CENPN,NCS1,CHST2,SESN3,CTGF,ZFP36,RGS3,STEAP2,AOX1,MTMR11,TFG,PACSIN1,LAMP2,LOC81691,SNTB2,PBK,HSPA12A,CASP9,MGAM,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SAV1,SLC25A5,TP53I3,ULK2,SGPP1,AHRR,SFXN1,KDSR,HLF,SLC25A4,RBM47,AREG,PTER,GNPTAB,TBX1,FAM110C,DHTKD1,SARAF,TMEM8B,RTN3,DLAT,KLF2,MRPL44,INPPL1,HLA-E,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,NOTCH2,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,NECAB3,BDH1,SORL1,CD70,PIKFYVE,CTSD,RIMS2,EEF1D,TMED2,FAM69A,EPB41L5,FADS2,DDB2,PMPCB,QSOX1,B3GNT7,ZNF84,MMD,MFI2,B9D2,AMER1,ANO6,PIP4K2C,VEZT,PKM,CYFIP2,KDM3A,GLT8D2,STX3,FAS,DGKH,SERTAD2,PRKAG2,DCK,NAB2,TCEAL4,FGD6,NR4A2,EFNA1,MAP3K5,NRBP1,IRF1,PLA2G4A,ELK4,SLC2A4,CEP70,ARMCX3,NLRX1,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,BROX,IRX4,KCTD12,CD274,EGR3,SNN,AIFM2,NUDT12,MNS1,GNB2,SLC25A35,CYHR1,APLP2,ZNF75D,CDKN1B,TNPO2,DAB2IP,LGMN,NR2C1,TMBIM1,GPX4,MYO5B,SEC23A,CDKN2AIP,TMEM43,DMTN,LYRM1,TEP1,COX11,SLC11A2,PRKCQ,AKR1E2,H2AFV,SP4,ZNF469,NIN,PRDM11,EPHA10,ZNF641,FYN,JAK1,PPP2R5A,ACYP1,CFAP45,STK26,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,HS3ST3B1,B4GALT3,NR3C2,ATMIN,MRPS9,WASF3,NUDT6,PCOLCE,ANKRD13D,JRKL,ATP9A,ARL4C,CCNJL,GPR180,APOBEC3H,SEPP1,SPR,SLC35G2,LGALS3BP,TEAD3,SIX4,AKIRIN1,FAM111A,OXCT1,PHF7,PTEN,PPP1R10,MGAT1,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,TAGLN2,CNOT6L,MAP3K7,GFI1,CNPY3,SPRY2,NCOA2,SMC4,PCCB,SHMT1,CASK,DENND1B,TEF,PARP4,VAMP3,FURIN,C1GALT1C1,GPLD1,NUCB1,RGS9,CTNS,PRDX3,SLC25A40,SERPINB5,CSTF2,GPER1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,ST13,CPT2,CAMKK1,HEBP1,UBE2Z,KIF2C,TAF6L,DNER,TSEN34,SH3KBP1,ABCD4,CHPF,MAGOHB,GRHL1,ZCCHC12,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,ANKRD12,KIF22,SUN3,RAB20,RP2,NFU1,MYH14,ARNT2,TECR,PTPRE,RASGRP1,ATL1,TDP1,SOD1,TRIM8,ASCL5,SYNE3,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,TCN2,SEC14L2,NEIL1,ZNF114,FASTKD1,UEVLD,TRIM45,IARS2,APBA2,RAP1GAP,PSMC1,PPP2R5D,CPPED1,STARD3NL,GRN,FAM213B,PIFO,PEX6,ELOVL7,ASL,ATP6V1E2,SAMD9,PHLPP1,ZNF432,CA2,EBF4,ZNF692,KNTC1,RFX5,ACAD8,NCEH1,LRIF1,HP1BP3,KDELR1,OXR1,GYLTL1B,HMG20B,FBXO8,EGFR,MUM1L1,GLCE,GNAS,FECH,NUDT16,TSC1,ONECUT1,PLPP3,UTP14C,PAPD5,NFKBIA,CDCA5,ALPK3,PITPNA,KIF12,KLF7,PROM2,SLC25A24,SPC25,IL15,SLC2A8,PSME2,MORC4,TDRKH,PATL2,MICALL2,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,SMO,GOT1,TWIST1,STEAP3,RPN2,F2R,PDIA6,LOXL1,SCYL3,HSPA2,GCA,ZNF525,TAF5,BAG4,KREMEN2,SLC39A8,OSTM1,AP5M1,IGSF8,ERBB2IP,DUSP4,SNAPC2,BFSP1,BHLHB9,PEX2,OVOL1,CANT1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,CDS2,SORT1,JKAMP,MIER3,AES,TRMT2B,POMGNT1,ZNF212,IRF2BPL,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,CKS1B,TRIM3,BRD7,HSPA13,MXD3,SUN2,SYPL1,RAB3B,CENPC,ASPM,NR4A1,MBNL3,OGDHL,POLD3,MPV17L2,SPAG1,HLA-B,GAREM2,MARC1,C2orf70,DHRS2,PRCP,HNRNPH2,TADA2B,UBE2D2,OTUB2,GLB1,HOXB13,GEM,ATP6V1C1,SOX8,LRRC57,ZNF596,SNPH |
| 1.484e-16 | -36.45 | KRIEG_HYPOXIA_NOT_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_NOT_VIA_KDM3A | 697 | 183 | 17758 | 2588 |
DOC2A,EPAS1,TMEM41B,FAM129B,CAMK1D,SDC1,CARD10,FANCI,ZYX,CTGF,CTNNB1,IMPAD1,DPYSL2,PPP1R16A,MITF,TRPC1,RAB20,SCARA3,TIPARP,IL1RAP,MGAT5,TUBA4A,OLFML2A,PCGF5,ING1,FBXL16,KCNIP3,CITED4,HN1L,TNIP1,ASXL1,HSPA12A,BNIP3L,LOXL2,SAV1,LHFPL2,ADRBK2,IRX3,DPYSL3,ANKRD10,ZNF114,GPRC5B,DHRS13,P4HA2,ZNF367,LEMD1,TANC2,SLC31A2,STARD13,MAFF,PRKAA2,SERPINE2,LGALS3,HJURP,NUAK1,SEC61G,RACGAP1,SORBS3,C11orf95,TTYH3,ITGA3,DAPK1,USP1,KNTC1,PANX2,MAPK7,KCTD3,GPR161,REC8,FADS2,QSOX1,DDB2,USP31,TESK1,RGMB,ANO6,MYBL2,ANTXR1,C3orf58,EGFR,FAS,CACHD1,SLCO4A1,SERTAD2,UAP1,NFKBIA,CDCA5,OSMR,STK39,CDK18,APOL2,NIPA1,CSRP2,EGLN1,ZSWIM5,AVPI1,CAPN12,FOXM1,TUBB4B,CAST,NDRG1,SOD2,BCL2L1,AIFM2,KBTBD11,PRR7,MNS1,KTN1,SYTL2,IER3,CCND1,NOV,KCTD15,GYS1,DAB2IP,RNF169,MAP3K3,SOAT1,SLC39A8,PLEKHO1,NUSAP1,ATP1B1,PKMYT1,IRS2,BFSP1,JAK1,C19orf66,KIAA1804,TRIOBP,BTBD6,KDELC2,CTDSP1,FAM134B,IER5L,ANXA3,CTHRC1,CDS2,ENO2,DCAF7,ARHGEF7,RASSF7,ARL4C,PDIA3,GMCL1,NTAN1,ETS1,SIRPA,ICAM1,SLC25A36,SNTA1,E2F7,PDCD10,ADD3,IRAK1,FJX1,PRC1,DRAM1,UBE2J1,IL17RA,BUB1,TMX1,DUSP1,PDGFC,PGM1,RAB3B,CASK,NR3C1,TACC1,PAPD7,CTNNAL1,GCLC,MPP1,AK4,DIAPH2,EMP3,KIF11,SPAG1,CRTC2,SWAP70,PLOD2,FHL1,NCAPG2,MELK |
| 1.634e-16 | -36.35 | CUI_TCF21_TARGETS_2_DN | MSigDB lists | CUI_TCF21_TARGETS_2_DN | 790 | 201 | 17758 | 2588 |
KIAA1462,EPAS1,VANGL1,GATA3,TEX2,MPP5,PDGFB,CARD10,SLC9A3R2,ZFYVE16,TGFBR3,CTGF,SHC3,DPYSL2,IL6ST,KLF3,PIK3CA,TRPC1,NTN4,SEMA3G,TIPARP,BTBD3,IL10RB,MGAT5,CD55,MARK1,CDYL,HSPA12A,RNF11,LOXL2,SLC17A5,LDB2,ULK2,ARHGEF26,COL12A1,SGPP1,OPTN,MPRIP,SERPINI1,GLCCI1,CHPT1,NXT2,LASP1,PARP12,SCOC,CDKN1C,PPP1R2,CHCHD7,TBC1D1,RASA2,PRKAA1,SLC36A4,PHLPP1,MERTK,ATG4A,WDFY1,UBE2Q2,FRY,ZNRF2,VASN,EXOC8,PRKG1,SLAIN2,C8orf58,SLC12A2,KANK3,MAST4,TRAK2,MMD,BTNL9,PARD3B,CALCRL,HEATR5A,SPTLC2,ANKRD29,RANBP9,C3orf58,RHPN1,PRX,TMEM30A,PELI2,NFKBIA,OSMR,SFMBT1,YOD1,SAMD8,PLD1,SHROOM2,TOB1,ADAMTS16,LMO7,MTM1,LZTFL1,TCF25,SORBS1,ARMCX3,UGP2,CAST,CTDSPL,IL13RA1,RASGRP3,KBTBD11,KIAA1147,ARHGEF16,PER2,ACAP2,ST5,FAM46A,RALB,FRYL,TMEM64,PDE4D,ACSL4,TMBIM1,EBAG9,SULF2,SEMA3B,DOCK4,ENPP4,MAP3K3,TMCC2,TMTC1,RFK,COQ10B,PTGER4,TANC1,CBL,DOCK5,FYN,PTPRJ,RTN4RL1,JAK1,SHROOM3,WWTR1,STAT1,PLEKHG1,VSIG10,RCAN2,HS3ST3B1,SLC27A3,LIFR,PRR15,ARNT,FAM134B,PLSCR4,PCOLCE,CPEB4,PARP14,BACE1,FRMD6,NES,COL4A5,CHAC2,TRIB2,ETS1,EFNB1,SH2D4A,SIRPA,TMCC3,KIF5B,FOXP2,AKIRIN1,SNX13,ZFX,ITGB8,SGK3,SGK1,ARVCF,CCDC82,FAM102A,ATP8B1,CITED2,P2RX4,ACBD5,PHF20L1,ARAP2,MOSPD2,PLSCR1,TACC1,RC3H2,PARP4,MBNL3,DIAPH2,C1GALT1C1,YES1,AIF1L,FNDC3A,ENDOD1,ARHGAP24,TIMP3,PLOD2,TADA2B,CSGALNACT1,ABCB1,UACA,ARRB1,SH3BGRL2,GEM,HIPK3,CPEB2,JARID2 |
| 2.614e-16 | -35.88 | ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | MSigDB lists | ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | 135 | 59 | 17758 | 2588 |
CCNE2,CCDC109B,DLGAP5,HJURP,FOXM1,MRPS15,PTTG1,NDC80,ERCC6L,CDCA3,CDCA8,KIF23,RACGAP1,KIF2C,CCNB1,STIL,FANCI,SAC3D1,TOP2A,APOBEC3B,PCNA,CCNA2,CA2,KIF14,PRC1,NEK2,BUB1,SMC4,CKS2,HMMR,PLK1,ZWINT,CENPA,KIF20A,ASPM,PBK,CDC20,MYBL2,NUSAP1,GGH,KIF20B,AURKB,CCNF,KIF11,CDK1,GINS4,PAFAH1B3,E2F1,NETO2,AURKA,MAPK13,KPNA2,HMGA1,CENPE,CCNB2,UBE2C,E2F8,ESPL1,MELK |
| 2.637e-16 | -35.87 | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | MSigDB lists | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | 435 | 129 | 17758 | 2588 |
UGT8,VANGL1,NDC80,KIF2C,CCNB1,CENPN,FANCI,MAGOHB,CALM2,CDKN2C,PCNA,NUP210,IMPAD1,TUBG1,TFG,MYBL1,IL1RAP,TUBA4A,CENPA,PBK,ITCH,CDYL,AURKB,F12,CDK1,GINS4,PRIM1,SFXN1,CARHSP1,ENPP1,DNM1L,KPNA2,E2F8,PRKAA2,RECQL,HJURP,STRN4,KIF23,CALM3,RACGAP1,GPSM2,SSX2IP,FCHO1,NEK2,CD70,KNTC1,LRIF1,MPHOSPH9,PSMA5,SNX7,KIF20A,CALM1,MYBL2,PYGL,WHSC1,CDK5R1,GNAS,FAM64A,TIMM8A,DCK,AURKA,SEMA3A,CCNB2,CBX5,CCNE2,DLGAP5,SPC25,FOXM1,PTTG1,SOD2,RGS20,PKP2,PRR7,APOBEC3B,SS18,MUC16,CCNA2,ARTN,KIF14,PLK4,ARL4D,EGLN3,CDKN2D,CKS2,SEPHS1,PPIF,SEC23A,PSRC1,RIPK2,CDC20,NUSAP1,CDC25C,RBL1,XRCC3,CMAS,DEPDC1,CKAP2,CENPI,CDCA8,ERCC6L,CDCA3,SLC9A2,TOP2A,PRC1,BUB1,MSH6,ATP2B1,HMMR,ZWINT,ASPM,RC3H2,AK4,UBAC1,GGH,KIF11,SKA1,PLOD2,TWSG1,NEIL3,NETO2,PPP2R3C,CENPE,HMGA1,WDR62,NUP37,UBE2C,NCAPG2,MELK,ACOT7 |
| 2.892e-16 | -35.78 | FOSTER_TOLERANT_MACROPHAGE_DN | MSigDB lists | FOSTER_TOLERANT_MACROPHAGE_DN | 398 | 121 | 17758 | 2588 |
PLA2G4A,SPRED1,AGRN,IL15RA,IL15,TRIP10,DGKA,ETNK1,C5orf30,COL18A1,IL13RA1,IL18,F11R,SNN,SPSB1,KREMEN1,KTN1,TNFSF9,CMTM6,MXD1,CDS1,RCN1,ZYX,SETDB2,ZFP36,SLC44A1,IRF2,MINPP1,F2R,SNX10,TIPARP,TIAM1,XKR8,MX1,GCA,PCGF5,RIPK2,SERTAD3,EZR,CD40,TMTC2,ASB13,TANC1,ALCAM,ADRBK2,SOCS3,NFIX,PTGS2,PTPRJ,C19orf66,RBL1,SECTM1,NFKBIZ,DDX58,ARHGEF3,FRMD4A,PARP14,TBC1D1,UBASH3B,SDC4,MIER3,C6orf106,HMGN3,ZNRF3,GPSM2,DUSP5,LMNA,RND1,ZDHHC21,OTUD1,CA2,IGSF9,ITGB8,CTSC,CENPJ,MCF2L,MGAT4A,SGK3,TPST1,DRAM1,TRIM21,TNFRSF12A,PIM1,CITED2,SLC45A3,PVRL4,MMD,NR3C1,CTNNAL1,PAPD7,DENND1B,BCL9,PLAUR,SPATA13,VEZT,KIAA1109,FNDC3A,FOS,DCP2,FAS,CD83,DGKH,ENDOD1,TMEM50B,CASP7,PVRL2,PLOD2,RND3,CSF1,TMEM30A,SLC2A6,SPINT2,RAP2C,NLRC5,UACA,ITGAV,ICOSLG,FZD5,IFIH1,KLF7,JARID2 |
| 3.134e-16 | -35.70 | intracellular organelle | cellular component | GO:0043229 | 11578 | 1877 | 17570 | 2579 |
HECA,IBTK,SLC25A13,PNPLA2,HEXB,RET,CCNO,TRAPPC8,TGOLN2,ISOC2,LACTB2,DPP8,SNX9,ZNF275,NPM2,CDKN2C,NAPG,MUC4,UBE2T,ATP13A3,DNM2,CRY2,PPP1CA,WBP4,TIPARP,CPE,MGAT5,DSTN,UXT,TMEM98,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,GINS4,LCP1,PIAS3,ENPP1,CARHSP1,PLCG1,MPRIP,MID1IP1,CELF5,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,HSPB1,STARD13,ANXA11,NXT2,SCN5A,GGA1,SEC61G,MTL5,RAB23,COX6C,FAM21C,MARCH8,TFAP4,FLII,RAC2,ZCCHC17,FRY,ATP5H,MEGF8,FLRT3,FBXO7,RANBP1,FBXL14,PCYOX1,SLAIN2,CADPS2,USP1,MYDGF,ZMYM1,MAPK7,MOXD1,MYLIP,NUP85,TTLL1,PPP6R1,MCCC2,REC8,PQLC3,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,GOLT1A,PSMA4,GNA11,SFXN5,PLIN5,IL1R1,FNTA,ETS2,APMAP,S100A5,DGAT2,STK39,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,DMPK,LFNG,APOO,PTTG1,MAPK4,MGST2,MVB12B,MOCS1,APPBP2,RCN1,RBM23,MUC16,CDH1,XYLT2,TAX1BP3,ZNF365,MYT1,SNX10,ETV4,MX1,SNX8,SEC61B,ERMP1,COL6A2,RIPK2,APOBEC3D,AGPS,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,GTF2A2,SNX12,TRIM7,ZNF618,COX20,EBF2,GABARAPL1,NFIX,PDLIM3,CCNB3,CDK19,SHROOM3,CORO1C,WFS1,PNPLA6,SLC25A30,ISOC1,MAPK12,MZT1,HSP90B1,GCAT,CKAP2,BACE1,TRAF2,DCAF7,ESRP1,BIK,SDC4,HABP4,FLOT1,CTSZ,ZNF219,HDGFRP2,IFT27,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,GPC3,MGAT4A,FAM20B,CST3,TUBGCP6,KLC3,BAX,IGFBP2,RAG1,MED22,PARP9,ACBD5,PLSCR1,TACC1,PIK3R1,DUSP23,MRS2,NUB1,UBE2A,PGBD1,AK4,RAB3IP,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,FAM3C,PLA2G15,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,SRSF9,ACOT7,PHC1,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,NDRG2,F11R,NENF,ITPR2,MGAT5B,SPTB,SLC9A3R2,FANCI,TFAP2E,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,P4HB,ARL1,PSMC2,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KRT80,KCNIP3,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CCBL2,CKAP2L,ARFRP1,EAF2,SESN1,DZIP1L,KDM4D,TNS4,TRIM9,HS6ST1,PLEKHG6,AGPAT2,KLF12,ZNF367,HOXA9,ARRDC1,KLF11,KPNA2,TC2N,MYL12B,RRAGD,RUNX2,LMTK3,PARP12,USH1C,LGALS3,HJURP,DNAJB2,FXYD3,PSMD7,SORBS3,ADCK5,RAB6A,HES2,RSAD1,MYO5C,B4GALNT1,TIMP1,RINL,KIF13B,TBCD,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,USP31,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,PRX,NMT2,C18orf8,CDK5R1,FOXD2,FA2H,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,AKIP1,CDAN1,CCNB2,USP43,RAD21,HOXB7,CTDSPL,TP53,P2RX7,RHPN2,BAHD1,STIL,PCBP1,EMP2,BCAP31,TMSB15B,SYTL2,IER3,TTC21B,PDGFA,KMT5C,WDR44,TACC2,BCL6,PLK4,ZDHHC23,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,PTGS2,TAPBP,ZNF628,IDE,RBL1,STK38,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ST3GAL1,BTBD6,FAM134B,ARFGEF3,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CPEB4,TAB3,CTSB,SCD5,MCTP2,CDCA8,ERCC6L,ERI2,GTF3A,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,TBC1D31,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,HMGCL,SYK,ATP2B1,GCNT1,WBP5,DUSP1,NFE2L3,P2RX4,HES1,RHOA,HMGN5,GUSB,PLAUR,PRICKLE1,DPP9,STMN3,MAML2,GGH,COL7A1,TXNDC11,RNPEP,BBS2,USP6,BCL10,DDX23,CNOT2,DDAH1,SCG2,NEIL3,NIPSNAP3A,FGF18,E2F1,SH3BGRL2,PTGES,HIPK3,ZBTB33,PKIA,GOLGB1,LAMP1,SLC35D2,TXN,PNISR,SSH1,HSPG2,TSC22D3,CUL1,PSME1,CAMK1D,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,PAK6,HELZ2,CYP1A1,ZNF823,STIM1,OSBPL3,PALD1,FOSB,POLL,KCNS3,IRF2,SNX16,HYLS1,TACSTD2,MARCH2,ZBTB18,SGCE,SPATA18,CDYL,BNIP3L,SLC35C1,KIF13A,LDB2,POR,RAB2B,PRIM1,PPP2R4,PRDM5,BMP1,NFKBIZ,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,PRKAA1,AKAP17A,TXNDC9,HERC6,APBA1,PDXDC1,PSIP1,SH3RF2,MESDC2,C9orf69,CALR,DOPEY2,ZNRF2,BHLHE41,RPL39,VASN,MSH2,DAPK1,TPST1,PRKG1,CACNA1D,DLX4,ZNF117,SYTL3,GPR161,TRAK2,PIGC,GID8,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,CALM1,WHSC1,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,PLEKHH2,TJP3,FAM64A,FAAH,WDR19,ZDHHC20,AGBL5,PIAS2,FAM83D,APPL2,ARAP1,SFMBT1,CABIN1,KLK7,SAMD8,ZBTB34,PLIN3,PER3,HOOK1,IFIH1,EHD1,FOXO6,SPRED1,KIF3C,TCF25,DLGAP5,TCTN2,GPR107,THRA,CERCAM,NDRG1,CCDC110,ATP2C2,FTH1,BCL2L1,FLT3,CYP39A1,ZFYVE9,EPM2A,APOBEC3B,CD46,NOV,CCNA2,ACAP2,RALB,RNASEH2A,PDE4D,OSBPL7,TSPAN1,SULT2B1,FLOT2,NAGA,MED30,SEMA3B,ATG4D,MSANTD4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,CLSTN1,KIF1C,RAD17,PYGO1,PKMYT1,CBL,B3GALNT2,ITPR3,TRIQK,ATP10D,CEP162,ZMPSTE24,DDOST,ACAD10,NGFRAP1,TRIOBP,SLC27A3,CBX7,COBL,MAMDC2,IGFBP6,DEPDC1,CENPI,NES,CBLL1,PBX3,PLD2,FBXO6,SPDL1,DNAH3,EFNB1,COX7A2,HLA-A,WWP2,SCML1,SLC25A36,CKAP5,E2F7,GOLGA2P5,RNF128,GNB5,FUT8,DRAM1,CD9,CITED2,TTPA,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,PAPD7,ZC3H11A,TCFL5,ZKSCAN2,DIAPH2,UBAC1,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,CRTC2,DCTN6,TIMP3,ACADSB,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,FZD5,ESPL1,DEF6,RGMA,CCNC,FAF2,UGT8,CRYM,UBE2Q1,VARS2,MPP5,COMMD5,MAP1LC3B,ERP29,SLC8B1,ECI1,TRIM68,ZFYVE16,RAB15,HSF2,CASC4,METTL7A,CDKL5,SIVA1,CEP78,TRPC1,ASH2L,CTTN,MYRIP,BTBD3,STK35,SP5,LAMP3,CERS2,CYP1B1,CXXC5,CENPA,ASXL1,LAP3,ITCH,ACBD3,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,TDRD7,SH3GLB2,ZNF165,SP6,GLA,CHPT1,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,ZNF395,SERPINE2,PPP1R12A,ETV5,ASB9,ABCG2,CALM3,PM20D2,TEC,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,CES2,FAM20C,OCRL,COL6A1,SUCO,PRKCI,SRP54,BRAT1,HLA-C,ZRANB1,GAD1,ETV7,CCDC88A,MDFI,SNX7,TPGS2,ELK3,KIAA1109,PRRC1,NUBP1,PDIK1L,C3orf58,STEAP1,RANBP9,SOX13,INSR,UAP1,TMEM30A,SH3BP4,SPAG7,RAB31,DCUN1D1,CTSA,DONSON,SHROOM2,JAK3,TOB1,APOL2,COL16A1,AFAP1,RARG,SNX30,DRD1,LMO7,CCNE2,DYNLRB1,SORBS1,PAX6,FAM214B,HDAC11,SOD2,PDIA5,COL18A1,OSR2,SAYSD1,PHLDA1,EXT2,MXD1,SAP130,ZNF687,CYP4F11,COX14,KIF14,REEP1,ZBTB49,ECE1,EPB41L4B,NFKB2,ETHE1,UPF3A,EBAG9,CHP1,SEPHS1,SOAT1,RFK,C3orf52,MRPS35,TMTC2,CD40,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,HSF4,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,PTBP3,SPTBN5,MAD2L1BP,ABCA1,KDELC2,GLIS3,FBLIM1,CIT,SHPRH,SH3D19,ARHGEF7,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,TMEM63A,KIF5B,TOP2A,MZT2A,CARD8,TAF1B,LLGL2,A4GALT,MYCL,TOX2,RRBP1,ZDHHC13,ACTA2,ARVCF,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,MYO5A,B3GALT6,PGM1,DCAF6,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,LEMD2,ARHGAP24,CTSL,CASP7,SWAP70,RND3,TRIM69,CTSV,RAP2C,CSGALNACT1,UACA,ARRB1,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,DOC2A,ACACB,KLK10,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,SMARCAL1,MMADHC,FBXO2,XIAP,DHX8,LGI3,CNTROB,MORF4L2,SYTL4,BARD1,KIF26A,PHF1,EPDR1,TP73,CALM2,DAPK2,WEE1,ZYX,PQLC2,PSMD1,AP1M2,RGS12,DNAH6,CABP1,CYP2S1,RDH14,KLF3,FUT1,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,ODF2L,APOBEC3G,ERAP2,TUBA4A,SPEF2,VPS11,SMARCA2,TNIP1,SERTAD4,SH3BGRL,SPRTN,RNF11,MTRF1L,LOXL2,ICMT,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,SERPINB6,MRPS28,RELL1,ARF6,E2F8,PDPR,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,CYP2J2,SOX9,SLC36A4,LMNA,ELF3,RAVER2,GNS,DNPEP,WDFY1,PRICKLE4,ZIC5,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,NAGPA,UFD1L,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,ILK,MEST,TP53INP2,SPTLC2,RHOB,DCP2,CYB5A,STK17A,DHX32,NAAA,NCOA3,SCARB2,MTFMT,TIMM8A,HTT,SETD3,TEX30,ITPR1,AURKA,DYSF,MDH1,ALG2,B4GAT1,NDE1,DRP2,ARPC2,ZNF502,RPS6KA3,CSRP2,XDH,EGLN1,MTM1,CCDC109B,GRHL2,TMSB15A,TUBB4B,GALNT12,ACTR8,ETNK1,RGS20,WDTC1,TESK2,PKP2,NUF2,PRKACA,APC2,KTN1,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,RNF169,CAMSAP3,SSH3,PSRC1,NRBF2,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,PXYLP1,RAB38,PEX5,STX10,SLC9A6,WWTR1,SIPA1L1,PDXK,RGS14,GEN1,ARNT,TTC8,FARP1,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,PDIA3,GMCL1,PKN1,TMA16,NUCB2,ETS1,GSTP1,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CAPN2,ANK1,ADD3,IRAK1,CTSC,ARSG,ANKS1B,ALG13,CALD1,FDXR,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,ZNF230,MAPK11,AK3,SGCB,ITM2C,TPCN1,S100A6,TMX1,CRTAP,POU6F1,MOB4,AMOTL2,LCA5,NUDT8,FMN1,CTNNAL1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,PLEKHA7,DBR1,NEURL1B,FAM109A,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,GALNT3,PITX2,BTG1,KIAA0141,CCDC6,ATXN7L3,NR1D2,ZFP30,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,FOXA1,MYL9,UNKL,UNC93B1,AGRN,CUL4B,EPHA4,SUDS3,MCCC1,NDC80,CDIPT,HDAC6,PDGFB,NUP62CL,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,ELF5,DUSP10,PXMP4,TLN2,TRAM1,MYBL1,DDX59,NEB,S100A13,CCDC38,ZNF462,PCGF5,ING1,HN1L,CITED4,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,RHEB,OPTN,IRX3,DPYSL3,PLCH1,MFAP3L,TBC1D17,CDCA4,MSL1,MAP2,WIPI1,P4HA2,DOLPP1,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,POMT1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DHRS3,PGAP1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,GATA2,CMTR2,PAK2,EXOC8,MDFIC,TMEM8A,ALDH3A2,PSMA5,C9orf9,CYP26B1,CHSY3,MRPS33,PCBP3,CORO2A,SPATA13,KBTBD8,TCF7,IFIT3,ZDHHC3,G2E3,SMN1,MAPKAPK2,EPN3,MOSPD3,COQ10A,H1F0,MFSD2A,ATP1B3,TMEM120A,CTBP1,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,ERBB2,CCNL1,FAM198B,LPIN3,CYP26A1,SDF4,PER2,CDK14,RAD23A,ATP6V0B,SRPX,LHX6,N4BP3,MINPP1,EGLN3,FAR1,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,EVA1A,TCEB2,FIGNL1,COQ10B,S100A4,CDC20,MYL12A,MYPOP,DNAJC10,ATP1A1,PSMD3,ZBTB6,RPL22,AIFM3,LTA4H,CNEP1R1,ZNF701,NDST3,POMGNT2,COPG1,ZC3HC1,MAN2B2,GSDMD,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,CD63,RUSC2,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,GBX2,CCDC92,CEP97,MAGEE1,SLC35B4,BUB1,ABCD1,KLF9,HEXIM2,CAMK2G,TLE6,MLEC,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,CARD19,TRIM35,FXR2,AKAP3,FNDC3A,BCAR1,MAPK8IP1,PRDX4,FUCA1,TMEM50B,SERPINA1,ZNF214,CDCA7L,NMI,PGRMC1,PPP2R3C,PKD2,SPCS3,ACADM,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,CFAP74,FAM129B,ATP8A1,KLC2,TAP1,GATA3,PLXNA1,CCNB1,PLA2G16,FAM101B,RIC1,CENPN,NCS1,CHST2,SESN3,CTGF,ZFP36,RGS3,STEAP2,TFG,PACSIN1,LAMP2,LOC81691,KIFC2,SNTB2,PBK,CASP9,AGO4,TNS1,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SAV1,SLC25A5,ULK2,SGPP1,AHRR,SFXN1,KDSR,HLF,SLC25A4,RBM47,AREG,PLK2,GNPTAB,TBX1,FAM110C,DHTKD1,SARAF,TMEM8B,TRAF5,RTN3,DLAT,DDX58,KLF2,MRPL44,INPPL1,FRMD4A,HLA-E,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,NOTCH2,KIAA1161,BMP2K,MECOM,SNX18,NECAB3,BDH1,SORL1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,FADS2,DDB2,PMPCB,QSOX1,B3GNT7,ZNF84,MMD,B9D2,AMER1,PIP4K2C,VEZT,PKM,KDM3A,GLT8D2,STX3,FRMD4B,FAS,DGKH,SERTAD2,PRKAG2,DCK,NAB2,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,IRF1,PLA2G4A,FRMPD3,ELK4,SLC2A4,CEP70,ARMCX3,NLRX1,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,IRX4,EGR3,SNN,AIFM2,NUDT12,MNS1,GNB2,SLC25A35,CYHR1,APLP2,ZNF75D,CDKN1B,TNPO2,DAB2IP,LGMN,NR2C1,TMBIM1,GPX4,MYO5B,SEC23A,CDKN2AIP,TMEM43,CAPN6,DMTN,LYRM1,TEP1,COX11,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,NIN,PRDM11,ZNF641,FYN,JAK1,PPP2R5A,CFAP45,STK26,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,HS3ST3B1,B4GALT3,NR3C2,ATMIN,MRPS9,WASF3,NUDT6,ANKRD13D,JRKL,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,SLC35G2,TEAD3,SIX4,RND1,AKIRIN1,SNTA1,FAM111A,OXCT1,PHF7,PTEN,PPP1R10,MGAT1,CENPJ,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,CNOT6L,MAP3K7,GFI1,CNPY3,SPRY2,NCOA2,SMC4,PCCB,SHMT1,CASK,ERMAP,DENND1B,MPP1,TEF,PARP4,VAMP3,FURIN,C1GALT1C1,GPLD1,NUCB1,RGS9,CTNS,PRDX3,SLC25A40,CSTF2,GPER1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,CPT2,CAMKK1,UBE2Z,KIF2C,TAF6L,DNER,TSEN34,SH3KBP1,ABCD4,CHPF,MAGOHB,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,ANKRD12,KIF22,SUN3,RAB20,RP2,NFU1,MYH14,ARNT2,TECR,PTPRE,RASGRP1,ATL1,TDP1,SOD1,TRIM8,ASCL5,SYNE3,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,TCN2,SEC14L2,CXXC4,NEIL1,ZNF114,FASTKD1,TRIM45,IARS2,APBA2,RAP1GAP,PSMC1,PPP2R5D,STARD3NL,GRN,FAM213B,PIFO,PEX6,ELOVL7,ATP6V1E2,SAMD9,PHLPP1,ZNF432,EBF4,ZNF692,KNTC1,RFX5,ACAD8,NCEH1,LRIF1,HP1BP3,KDELR1,OXR1,GYLTL1B,HMG20B,FBXO8,EGFR,GLCE,GNAS,FECH,NUDT16,TSC1,ONECUT1,PLPP3,UTP14C,PAPD5,NFKBIA,CDCA5,ALPK3,KIF12,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,SLC2A8,PSME2,MORC4,TDRKH,ZMYND10,PATL2,MICALL2,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,SMO,GOT1,TWIST1,STEAP3,RPN2,F2R,PDIA6,LOXL1,SCYL3,HSPA2,ZNF525,TAF5,BAG4,KREMEN2,OSTM1,AP5M1,ERBB2IP,DUSP4,SNAPC2,BFSP1,BHLHB9,PEX2,OVOL1,CANT1,CYP2U1,AKNA,SGOL1,REEP4,CBX4,ANXA3,CDS2,SORT1,JKAMP,FRMD6,POC1B,MIER3,AES,TRMT2B,POMGNT1,ZNF212,SAC3D1,IRF2BPL,SNX13,MDM1,ADORA1,GALNS,KIAA0319,CKS1B,TRIM3,BRD7,HSPA13,MXD3,SUN2,SYPL1,ADAM17,RAB3B,CENPC,ASPM,NR4A1,MBNL3,OGDHL,POLD3,MPV17L2,SPAG1,MAP1B,KLHL2,HLA-B,MARC1,C2orf70,DHRS2,PRCP,HNRNPH2,TADA2B,UBE2D2,OTUB2,GLB1,HOXB13,GEM,ATP6V1C1,SOX8,ZNF596,SNPH |
| 3.534e-16 | -35.58 | positive regulation of catalytic activity | biological process | GO:0043085 | 1521 | 340 | 16441 | 2455 |
TXN,RET,CUL1,NRG2,PSME1,CCNB1,SNX9,CARD10,RIC1,ELMOD2,GRM5,TP73,NPM2,CALM2,PAK6,ARHGAP42,PSMD1,RGS12,CTGF,RGS3,SERINC2,PIK3CA,DNM2,TIAM1,NEK4,ACVR1C,CASP9,PRKAR2B,AURKB,POR,ARF4,ABR,ARHGEF26,PLCG1,MID1IP1,SH2D3C,PPP2R4,NOD2,MAP3K11,AGFG2,STARD13,GAB1,FGD1,TBC1D1,ITGA6,PRKAA1,TFAP4,RALGPS2,CYR61,SNX18,FAM13B,RANBP1,NEK2,MSH2,DAPK1,MAP3K9,SORL1,NCAM1,GPR161,MMD,TBC1D8B,MAPKAPK3,CALM1,EPHA1,CYFIP2,ILK,PSMA4,PLIN5,RASA1,FAS,MMP15,FNTA,PRKAG2,SEMA4D,ITPR1,ARAP1,FGD6,NR4A2,STK39,EFNA1,MAP3K5,XDH,DOCK9,PLEKHG3,ARHGAP11A,SPRED1,GRHL2,RALBP1,IQGAP1,RGS20,MGST2,PRKACA,FLT3,EPS8L2,CCND1,ST5,ACAP2,SH3BP1,RALB,TAX1BP3,CDKN1B,DAB2IP,RASGEF1A,TBC1D10B,DOCK4,PSRC1,RIPK2,FZD4,PFKFB2,PRKCQ,SLC11A2,ATP1B1,ITPR3,IRS2,FYN,JAK1,NGFRAP1,STK26,CORO1C,WFS1,SIPA1L1,PLEKHG1,KIAA1804,SLC27A1,NRG1,RGS14,DENND5B,MAPK12,PRKAR1A,ARHGEF3,FARP1,PCOLCE,TAOK2,NKX3-1,DEPDC1,TRAF2,SDC4,PKN1,ARHGEF40,FGF19,ICAM1,PDCD10,IRAK1,CTSC,PTEN,KNDC1,MCF2L,BAX,MAPK11,ERBB3,MAP3K7,SPRY2,MSH6,FARP2,RASGRF1,PDGFC,ARAP2,ARHGEF28,PLSCR1,DENND1B,RAPGEF2,GRIN1,RAB3IP,GRTP1,TXK,GPLD1,RGS9,FGFR2,RCBTB2,RIN3,ARFGAP3,GRIN2D,GPER1,CENPE,FZD5,CD81,CCNC,CASP3,AGRN,CAMKK1,EPHA4,ARFGEF1,DNAJB11,F11R,ITPR2,PDGFB,ERP29,DENND2D,SPTB,ARHGEF10L,SIPA1L2,PCNA,RABEP2,CTNNB1,NPNT,SHC3,ARHGEF37,CDKL5,ARL1,PSMC2,DLG1,RGS5,RP2,SLC39A10,RASGRP1,PLK1,SOD1,ARHGDIB,PRKRA,CDK1,VCP,EDNRA,SEC14L2,PLEKHG6,TBC1D17,ARHGEF19,GPRC5B,MADD,CAB39,RAP1GAP,PSMC1,PIFO,ARAP3,PPP1R12A,RASA2,PSMD7,CALM3,RACGAP1,DOCK11,FBLN1,DUSP5,BMP2,NOXA1,RINL,OCRL,TBCD,PAK2,FNIP1,MDFIC,PIM1,WNT3A,PLCB2,ALS2CL,PSMA5,CCDC88A,MDFI,SPATA13,STRADB,PDE5A,FBXO8,SCRIB,BCL2L13,EGFR,CDK5R1,RASGRP2,GNAS,BCAR3,MAPKAPK2,TSC1,INSR,CSF1,DCUN1D1,CTSA,ATP1B3,JAK3,DRD1,AVPI1,PSME2,ERBB2,P2RX7,RASGRP3,CCNL1,EMP2,STIL,BCAP31,ARHGEF16,PDGFA,KIF14,CDH3,EGLN3,F2R,HSPA2,GM2A,DVL2,FRS3,MAP3K3,SIRT1,TIMP2,AKT1,RFK,CDC20,CD40,DOCK5,MAP3K6,ARHGAP35,DNAJC10,PSMD3,MMP17,SPTBN5,EFNA5,ARHGAP4,ARFGEF3,GCLM,PINK1,TAB3,ARHGEF11,DAP,ARHGEF7,GNAL,PSMD10,TGFBR1,SBF1,PARM1,SYDE2,SNX13,CARD8,ADRBK1,ADORA1,LLGL2,IQGAP3,SYK,RPGR,CAMK2G,RHOA,ADAM17,PSMB4,RGCC,BCL10,ARHGAP24,CASP7,FGF18,ARRB1,PPP2R3C,PKD2,UBE2C,TBC1D4,ARHGEF9,RAB3IL1,ARHGEF4,NGEF |
| 4.349e-16 | -35.37 | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | 363 | 113 | 17758 | 2588 |
MYL9,TCF25,DLGAP5,PTTG1,PDIA5,ERBB2,COL18A1,NDRG2,PDGFRL,KIF2C,CCNB1,EMP2,MNS1,CENPN,MOCS1,SH3KBP1,UHRF1BP1L,APOBEC3B,CDKN2C,P4HB,KIF14,SLC46A1,CAPG,PLK4,CLDN4,RNASEH2A,APIP,NFKB2,CERS2,PLK1,PSRC1,TIMP2,CENPA,S100A4,CDCA2,LOXL2,SLC17A5,PPP1R14C,CDK1,DAG1,FYN,CDCA4,PAFAH1B3,RBL1,MYLK,KPNA2,PIK3C2B,RELL1,PRSS8,ENO2,DEPDC1,CIT,BLVRB,CDCA8,SELL,NES,KIF23,RACGAP1,SLC36A4,SLC1A3,PDXDC1,NRP2,IL17RB,TOP2A,CA2,CES2,CYR61,PIK3AP1,MGAT1,VASN,NEK2,PRC1,SLC44A2,ADAM15,H2AFY,CKS1B,BUB1,TAGLN2,KLF9,ERBB3,SLC12A2,MPHOSPH9,CAMK2G,EPHX1,AMOTL2,SUN2,ZWINT,PSMB4,NR4A1,SPATA13,MYBL2,WHSC1,PRRC1,NEURL1B,KIF11,PITX2,TJP3,PVRL2,H1F0,DBI,FAM83D,E2F1,AURKA,SFMBT1,CTSA,EFNA1,CENPE,GEM,NCAPG2,CCNB2,UBE2C,MELK,ACOT7 |
| 4.768e-16 | -35.28 | positive regulation of molecular function | biological process | GO:0044093 | 1782 | 386 | 16441 | 2455 |
TXN,ADD1,TRIM5,RET,CUL1,NRG2,GATA3,PSME1,CAMK1D,CCNB1,SNX9,CARD10,RIC1,ELMOD2,GRM5,TP73,NPM2,CALM2,PAK6,PSMD1,ARHGAP42,RGS12,CTGF,STIM1,RGS3,SERINC2,PIK3CA,DNM2,TIAM1,NEK4,ACVR1C,CASP9,PRKAR2B,AURKB,SAV1,POR,ARF4,ARHGEF26,ABR,PLCG1,MID1IP1,PLK2,SH2D3C,PPP2R4,NOD2,MAP3K11,AGFG2,TRAF5,STARD13,GAB1,FGD1,DDX58,TBC1D1,ITGA6,PRKAA1,TFAP4,RALGPS2,CYR61,SNX18,FAM13B,RANBP1,NEK2,MSH2,DAPK1,MAP3K9,SORL1,NCAM1,GPR161,EPB41L5,MMD,TBC1D8B,MAPKAPK3,CALM1,EPHA1,ILK,CYFIP2,PSMA4,PLIN5,RASA1,FAS,MMP15,NCOA3,FNTA,PRKAG2,HTT,SEMA4D,ITPR1,ARAP1,FGD6,NR4A2,STK39,EFNA1,MAP3K5,TMEM173,XDH,DOCK9,PLEKHG3,ARHGAP11A,SPRED1,GRHL2,LFNG,RALBP1,IQGAP1,RGS20,MGST2,PRKACA,FLT3,EPS8L2,CCND1,ST5,ACAP2,SP100,SH3BP1,RALB,CDKN1B,TAX1BP3,DAB2IP,RASGEF1A,TBC1D10B,DOCK4,PSRC1,RIPK2,FZD4,PFKFB2,PRKCQ,SLC11A2,ATP1B1,ITPR3,GTF2A2,EBF2,IRS2,FYN,JAK1,NGFRAP1,STK26,WFS1,CORO1C,SIPA1L1,PLEKHG1,KIAA1804,SLC27A1,NRG1,RGS14,DENND5B,MAPK12,PRKAR1A,TCAF1,CTHRC1,ARHGEF3,FARP1,PCOLCE,NKX3-1,TAOK2,DEPDC1,TRAF2,SDC4,FLOT1,PKN1,ARHGEF40,FGF19,ICAM1,PDCD10,IRAK1,CTSC,PTEN,KNDC1,MCF2L,SGK3,BAX,MAPK11,ERCC2,ERBB3,MAP3K7,SPRY2,TRIM62,NCOA2,MSH6,FARP2,RASGRF1,PDGFC,ARAP2,ARHGEF28,PLSCR1,DENND1B,RAPGEF2,GRIN1,RAB3IP,GRTP1,TXK,GPLD1,CRTC2,RGS9,FGFR2,RCBTB2,PRDX3,RIN3,ARFGAP3,GRIN2D,GPER1,CENPE,FZD5,CD81,FOXA1,CCNC,CASP3,AGRN,CAMKK1,EPHA4,ARFGEF1,DNAJB11,F11R,ITPR2,PDGFB,ERP29,DENND2D,SPTB,ARHGEF10L,SIPA1L2,PCNA,RABEP2,CTNNB1,NPNT,SHC3,CDKL5,ARHGEF37,ARL1,PSMC2,DLG1,RGS5,RP2,SLC39A10,RASGRP1,PLK1,SOD1,TRIM8,ARHGDIB,PRKRA,CDK1,VCP,EDNRA,KDM4D,SEC14L2,PLEKHG6,TBC1D17,ARHGEF19,GPRC5B,MADD,CAB39,RAP1GAP,PSMC1,PIFO,ARAP3,PPP1R12A,RASA2,PSMD7,CALM3,RACGAP1,DOCK11,FBLN1,DUSP5,BMP2,NOXA1,RINL,OCRL,PAK2,TBCD,PRKCI,FNIP1,MDFIC,PIM1,WNT3A,PLCB2,ALS2CL,PSMA5,CCDC88A,MDFI,SPATA13,STRADB,PDE5A,FBXO8,SCRIB,BCL2L13,EGFR,CDK5R1,RASGRP2,GNAS,MAPKAPK2,BCAR3,TSC1,INSR,PLPP3,CSF1,NFKBIA,DCUN1D1,CTSA,ATP1B3,JAK3,DRD1,AVPI1,PSME2,ERBB2,P2RX7,RASGRP3,CCNL1,EMP2,STIL,BCAP31,ARHGEF16,PDGFA,KIF14,PLCG2,SMO,CDH3,TWIST1,EGLN3,NFKB2,F2R,HSPA2,GM2A,DVL2,FRS3,CTH,CHP1,MAP3K3,SIRT1,TIMP2,AKT1,RFK,CDC20,CD40,DOCK5,MAP3K6,ARHGAP35,DNAJC10,PSMD3,MMP17,SPTBN5,EFNA5,PLXND1,ARHGAP4,ARFGEF3,ANXA3,GCLM,PINK1,TAB3,ARHGEF11,DAP,ARHGEF7,GNAL,PSMD10,TGFBR1,SBF1,PARM1,SYDE2,SNX13,CARD8,ADORA1,ADRBK1,LLGL2,SGK1,TRIM21,IQGAP3,SYK,RPGR,CAMK2G,HES1,ADAM17,RHOA,PSMB4,WNT10B,PLAUR,AMFR,RGCC,BCL10,ARHGAP24,CASP7,FGF18,ARRB1,PPP2R3C,PKD2,TBC1D4,UBE2C,ARHGEF9,RAB3IL1,ARHGEF4,NGEF |
| 4.775e-16 | -35.28 | kidney-other-neoplasm | COSMIC cancer mutations | kidney-other-neoplasm | 11169 | 1805 | 17775 | 2585 |
HECA,FAM160B1,IBTK,GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,TRAPPC8,BAIAP3,LACTB2,SNX9,SPSB1,CARD10,LTBP3,ZNF275,CDKN2C,NPM2,NAPG,PHYHIP,PAQR5,ATP13A3,DNM2,TMEM37,WBP4,TIAM1,IL10RB,CPE,TIPARP,MGAT5,NEK4,UXT,DSTN,CDA,KDELR3,TMEM151A,PRKAR2B,PNKD,ABR,ARF4,LCP1,ENPP1,PLCG1,CARHSP1,C17orf51,ATP7B,CELF5,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,STARD13,ANXA11,ZNF720,NXT2,SCN5A,SEC61G,GGA1,MTL5,RAB23,GPSM2,CCDC64B,FAM21C,TTYH3,MARCH8,TFAP4,RAC2,ZCCHC17,FRY,RIMS3,FBXO7,FBXL14,MAP3K9,SLAIN2,CADPS2,USP1,USP38,ALPK1,CNGA1,MAPK7,ZMYM1,MOXD1,MYLIP,DGKG,NUP85,MCCC2,HPS3,PQLC3,FHL2,KIF20B,NPHP3,DPYSL4,PCTP,SFXN5,GNA11,PSMA4,IL1R1,CACHD1,FNTA,ETS2,S100A5,DGAT2,CLMN,OSCP1,CBX5,TMEM173,DOCK9,WDR63,NQO1,PTTG1,RHBDL3,APOO,MGST2,FAM91A1,MOCS1,KIAA1147,APPBP2,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,TAX1BP3,LRP11,MYT1,SNX10,TMCC2,MX1,SNX8,SEC61B,COL6A2,ERMP1,RIPK2,PFKFB2,AGPS,PTPN9,SEPT6,SAT1,VPS4B,XRCC6BP1,TANC1,ZNF618,SNX12,EBF2,GABARAPL1,NFIX,SPIN3,PDLIM3,CCNB3,SHROOM3,CDK19,CORO1C,DMWD,PRIMA1,SLC25A30,ISOC1,MAPK12,CTHRC1,MZT1,HSP90B1,MPZL1,FAM189A2,CKAP2,BACE1,TRAF2,HABP4,CCM2,SDC4,OSGIN2,FLOT1,BTN3A1,SLC25A43,CTNNBIP1,ZFX,PDCD10,ITGB8,KNDC1,GPC3,MGAT4A,TMEM62,TUBGCP6,FAM20B,BAX,FAM102A,IGFBP2,CASD1,PARP9,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,AK4,PGBD1,RAB3IP,C4orf27,PROM1,LDLRAP1,PLOD2,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,PPM1H,FBXO44,ITGAV,CMPK2,CD81,ACOT7,PHC1,TLL2,TMEM131,CCNI,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,NENF,GALM,MGAT5B,ITPR2,SPTB,TFAP2E,PLS3,SUSD2,CPNE2,INPP5E,ENTPD4,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,NPNT,IL6ST,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,KRT80,THRB,PTPN18,MARK1,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,CCBL2,CKAP2L,NKAIN1,ARFRP1,EAF2,SESN1,TRUB1,DZIP1L,TRIM9,TNS4,PLEKHG6,PI4K2B,HS6ST1,TRAM2,KCNMB4,AGPAT2,KLF12,ZNF367,KLF11,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,PARP12,RUNX2,USH1C,HJURP,RASA2,PSMD7,PDCL,ADCK5,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,FAR2,WNT3A,NTN1,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,ZSCAN12,BCL2L13,CDK5R1,NMT2,C18orf8,RASGRP2,FA2H,COL13A1,KBTBD2,PHLPP2,OTUD6B,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,RAD21,HOXB7,CTDSPL,TMX4,TP53,RHPN2,P2RX7,EMP2,STIL,SYTL2,PDGFA,TTC21B,WDR44,TACC2,LMO4,PPME1,BCL6,ZDHHC23,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,RBL1,ABHD12,STK38,MAOA,CHMP4B,XRCC3,EFNA5,SYT13,ST3GAL1,BTBD6,FAM134B,BIN1,CMAS,PINK1,CDH22,CPEB4,TAB3,SCD5,GNAL,MCTP2,HAL,CDCA8,ERCC6L,GTF3A,GDF15,LBR,AIP,PARM1,IL22RA1,VPS26A,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,C16orf74,LYPD6,GTF2F2,FAM63A,IL17RA,SGK1,TSPAN13,CPLX1,ALDH7A1,HMGCL,FAM134C,ATP2B1,NFE2L3,P2RX4,FBLN5,MOSPD2,GUSB,PLAUR,DPP9,MAML2,GGH,RNPEP,TXNDC11,BBS2,DGKE,USP6,BCL10,DDX23,CNOT2,DDAH1,NEIL3,FGF18,SH3BGRL2,PTGES,HIPK3,ARHGEF4,GOLGB1,FAM171B,LAMP1,SLC35D2,TXN,LGR4,SSH1,HSPG2,VANGL1,TSC22D3,C1orf198,CUL1,PDGFRL,NANS,VASH1,OAT,PJA2,PICK1,SLC9A7,PAK6,ANKS6,STIM1,OSBPL3,POLL,PIK3CA,IRF2,SNX16,ACVR1C,CDYL,BNIP3L,KIF13A,LDB2,POR,PRIM1,ANKRD10,GDE1,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,SERPINI1,F2RL1,CCDC97,FGD1,SEMA6B,RECQL,MRC2,SCOC,TBC1D1,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,SH3RF2,MESDC2,CALR,DOPEY2,RALGPS2,ZNRF2,AIM1,MSH2,DAPK1,TMEM51,PRKG1,TPST1,OSTF1,C8orf58,CACNA1D,KCTD3,ZNF117,SYTL3,GPR161,TRAK2,GFPT1,GCC2,PRODH,KCNJ12,KLK5,CEP89,LPGAT1,CALM1,DCHS1,PYGL,WHSC1,ANTXR1,NFIB,PDE11A,MMP15,AP1AR,NT5C2,SLCO4A1,PLEKHH2,TJP3,FAAH,PELI2,C1orf21,FAM83D,MPP2,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,SAMD8,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,KIF3C,FOXO6,TCF25,TCTN2,DLGAP5,CAPN12,GPR107,ST14,CCDC110,THRA,NDRG1,RALBP1,ATP2C2,BCL2L1,TMEM170B,TMEM19,FLT3,CYP39A1,ART5,ZFYVE9,EPS8L2,EPM2A,CD46,APOBEC3B,NOV,ACAP2,RALB,BRI3,EPHB4,RNASEH2A,PDE4D,OSBPL7,FLOT2,MED30,NAGA,COG2,CYB5R2,DRAP1,PANK1,CLSTN1,UTRN,KIF1C,TMEM144,ATP1B1,PYGO1,CBL,B3GALNT2,ITPR3,ASB13,ALCAM,ATP10D,FZD7,ZMPSTE24,AMZ2,DDOST,POPDC3,ACAD10,TSPAN18,ZNF704,FAM195A,COBL,CBX7,MAMDC2,PRKAR1A,PLSCR4,HAPLN3,SLC41A1,CENPI,EPS8,CBLL1,EFHD2,HERC5,PBX3,PLD2,FBXO6,DNAH3,FGF19,WWP2,SLC25A36,CKAP5,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,TTPA,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,LONRF3,ZC3H11A,PAPD7,TCFL5,ZKSCAN2,FBXO9,DIAPH2,C2orf69,UBAC1,YES1,GRTP1,ARSK,KIF11,CDK5RAP1,CRTC2,DCTN6,ACADSB,DGCR2,SEC14L4,RIN3,TBX18,ABCB1,ERAP1,WDR62,WDR91,ESPL1,DEF6,MELK,RGMA,FAF2,UGT8,CRYM,UBE2Q1,MPP5,ERP29,TRIM68,ADPRHL1,ZFYVE16,EPCAM,RAB15,SIPA1L2,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,STK35,LAMP3,CXXC5,CENPA,ASXL1,LAP3,ITCH,USP18,ACBD3,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,MADD,TDRD7,ZNF165,SP6,CHPT1,CAPN1,NR2C2,CD99,LASP1,ARAP3,PPP1R2,PPP1R12A,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,PM20D2,FAM81A,QSOX2,TYW3,NOXA1,PFKL,FAM20C,OCRL,COL6A1,MTMR10,PRKCI,SRP54,LIMCH1,BRAT1,C10orf54,NPTN,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,ELK3,PODXL2,SPA17,VWA1,PDE5A,KIAA1109,PRRC1,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,RHPN1,SOX13,INSR,UAP1,TMEM30A,SPAG7,DCUN1D1,SH3BP4,RAB31,NXPH4,SHROOM2,TMEM14A,JAK3,COL16A1,APOL2,RARG,AFAP1,SNX30,CCNE2,LMO7,NCKAP5,DYNLRB1,LZTFL1,PAX6,SORBS1,SOD2,PDIA5,COL18A1,IL27RA,MRAS,KCTD9,MXD1,CYP4F11,KIF14,REEP1,ZBTB49,DIXDC1,EPB41L4B,ECE1,ETHE1,UPF3A,EBAG9,SOAT1,PTPRU,MRPS35,GLO1,CD40,TMTC2,CDC25C,PDHX,CASP4,ARHGAP35,SOCS3,ALDH5A1,STAT6,SECTM1,PTBP3,TLE1,RCAN2,SPTBN5,MAD2L1BP,ABCA1,LNP1,KDELC2,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,ARHGEF7,SH3D19,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,RBP7,XPR1,HMGXB4,SYDE2,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,H2AFY,ARVCF,C12orf75,SLC35A1,RPGR,MYO5A,RBMS2,PGM1,DCAF6,SYBU,RC3H2,TTC7A,FAM73B,NDRG3,TCEAL8,LEMD2,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,TRIM69,RND3,FIBCD1,RAP2C,SPINT2,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,NGEF,ACACB,TRIM24,ADD1,IL15RA,MRPS15,AASS,DNAJC3,FBXO2,MMADHC,XIAP,CACNA2D2,SMARCAL1,DHX8,NRG2,LYNX1,LGI3,SYTL4,CNTROB,CA8,BARD1,KIF26A,EPDR1,DAPK2,TP73,WEE1,PSMD1,TGFBR3,RGS12,AP1M2,ARHGAP42,KIAA1107,DNAH6,CYP2S1,CABP1,KLF3,ALDH1A3,ACOX2,TINAGL1,PIK3CD,ODF2L,ERAP2,TUBA4A,NWD1,TNIP1,SH3BGRL,RNF11,LOXL2,PPP1R14C,ICMT,MYOM1,CYP4F3,COL12A1,SLC44A3,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,MRPS28,RELL1,LSM14B,ARF6,PDPR,GAB1,E2F8,FAM169A,ALDH6A1,TMTC3,CYP2J2,SOX9,STRN4,MERTK,LMNA,RAVER2,GNS,DNPEP,WDFY1,FAM189A1,CD22,FAM13B,STT3B,NDUFA12,C9orf72,NAGPA,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,MEST,SPTLC2,DCP2,CYB5A,STK17A,DHX32,PTPRF,SCARB2,NAAA,NCOA3,MTFMT,HTT,SEMA4D,SETD3,DYSF,AURKA,OSMR,FBXO27,ARPC2,DRP2,NDE1,TRPC3,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,ACTR8,WDTC1,RGS20,ETNK1,PKP2,IL13RA1,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,UHRF1BP1L,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,CAMSAP3,PSRC1,LGALS8,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,NUSAP1,RAB38,IRS2,PEX5,TTC12,SIPA1L1,WWTR1,PLEKHG1,PDXK,RGS14,ARNT,TTC8,FARP1,TNRC6C,TAOK2,PARP14,PLEKHJ1,MAN1A2,PDIA3,GMCL1,ANO9,PKN1,NUCB2,TSPAN17,SRPX2,TIPRL,NEO1,CAPN2,ADD3,SLC27A6,ANKS1B,ARSG,CTSC,KCNK5,CALD1,NKAPP1,MAPK11,ZNF230,WWP1,AK3,NPTXR,SGCB,CRTAP,HCN3,AMOTL2,POU6F1,LCA5,CTNNAL1,FAM160A1,FMN1,RAPGEF2,EIF5A2,GRIN1,PLEKHA7,DBR1,BLVRA,NEURL1B,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,DCAF10,GALNT3,BTG1,KIAA0141,NR1D2,CCDC6,ZFP30,ARFGAP3,CENPE,NUP37,SHOX2,USF2,DCBLD1,CYBRD1,SIGIRR,AGRN,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,MCCC1,HDAC6,NUP62CL,SDC1,PIGL,SHC3,ELF5,DDHD2,DUSP10,RGS5,TNFRSF18,ANO4,TLN2,PXMP4,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,HN1L,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,FAM212B,IDH1,CLCN2,LHFPL2,RHEB,VCP,PLEKHB1,IRX3,OPTN,DPYSL3,PLCH1,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,PRKAA2,BMF,UBASH3B,ZCCHC24,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,CORO1B,BMP2,KIAA0895,VASP,DAZAP1,IGF1R,GATA2,MDFIC,ALDH3A2,PSMA5,ABCC1,C9orf9,CHSY3,CYP26B1,WDR72,TESK1,CORO2A,TCF7,EIF2AK1,IFIT3,UNC45B,ANKRD29,ZDHHC3,G2E3,MOSPD3,DHDH,PVRL2,PRPS2,LTBP2,ATP1B3,CTBP1,RNF146,NIPA1,KCNAB3,NF2,UGP2,UPF3B,FOXM1,XYLT1,DGKA,CCDC68,ERBB2,CCNL1,LPIN3,C1orf116,PER2,RAD23A,CDK14,ATP6V0B,SRPX,EFR3A,GYS1,MINPP1,EGLN3,SCN2A,FAR1,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,TCEB2,CDC20,MYPOP,DNAJC10,DUOX1,ATP1A1,PRRT4,RTN4RL1,C19orf66,PTK7,PSMD3,ADAMTS14,ANXA9,LTA4H,AIFM3,ZNF701,NDST3,ZC3HC1,CMTM4,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,RUSC2,DAP,BLVRB,GABRG2,JAG2,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CEP97,MAGEE1,SLC35B4,ABCD1,BUB1,KLF9,HEXIM2,SLC45A3,CAMK2G,FAH,IGDCC4,DLGAP1,HMMR,CRB3,NR3C1,AMFR,LITAF,PPARA,TRIM35,CAPNS1,AKAP3,FXR2,FNDC3A,BSDC1,MAPK8IP1,CD83,PRDX4,FUCA1,TMEM50B,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,PKD2,TBC1D4,UBE2C,NDFIP1,GAA,ACVR1,PPP4R4,TTC39B,TMEM41B,ATP8A1,FAM129B,KLC2,PPFIBP2,GATA3,PLXNA1,PLA2G16,SLC20A1,ELMOD2,NCS1,SESN3,ELMO2,RGS3,PRICKLE3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,RCAN3,SMYD5,LAMP2,ORAI2,LOC81691,TMEM68,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,SLC17A5,SAV1,CCNF,ZFAND5,SLC25A5,SPNS3,ULK2,ARHGEF26,SGPP1,AHRR,SFXN1,KDSR,SLC25A4,PTER,TBX1,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,RTN3,DLAT,DDX58,INPPL1,CDK17,FRMD4A,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,ISYNA1,NOTCH2,SLC1A3,PRRG4,MECOM,ITGA3,CYR61,PIK3AP1,SLC16A6,NECAB3,BDH1,RUNDC3B,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,CTSD,RIMS2,TMED2,TSPAN33,EEF1D,FAM69A,DNAI1,EPB41L5,PMPCB,DDB2,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,MICB,PTPRH,PIP4K2C,KCTD20,VEZT,FAM133B,PKM,KDM3A,FBXO10,GLT8D2,STX3,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,TMEM54,ISM1,DCK,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,EFNA1,MAP3K5,NRBP1,IRF1,PKD1L2,FRMPD3,PLA2G4A,PLEKHG3,SLC2A4,CEP70,TRIP10,NLRX1,BROX,CAST,SUZ12,IQGAP1,RPS6KA1,EGR3,CD274,NUDT12,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,DOK4,FICD,CDKN1B,CNNM4,IFIT1,LGMN,PHKA2,NR2C1,MYO5B,SLC5A11,SEC23A,CAPN6,TEP1,PRKCQ,BCL7B,AKR1E2,SP4,ZNF469,PRDM11,CMTM7,NIN,OSBPL2,EPHA10,FYN,PPP2R5A,JAK1,KIAA1804,STAT1,PPP1CB,NRG1,KLF5,MLKL,HS3ST3B1,ZC3H12B,B4GALT3,NR3C2,DENND5B,OTUD5,MRPS9,WASF3,ARHGEF3,SLC16A14,JRKL,ATP9A,CCNJL,GPR180,SEPP1,PNPLA5,LGALS3BP,TMCC3,SNTA1,PHF7,OXCT1,PTEN,CENPJ,PRC1,ATP8B1,SLC44A2,MAP3K7,GFI1,TRIM62,NCOA2,OSGIN1,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,C1GALT1C1,LRRC1,GPLD1,RGS9,NUCB1,PRDX3,AMMECR1,SLC25A40,CSTF2,CCDC69,PGM2L1,GRIN2D,SLC25A38,ARSB,NCAPG2,OCLN,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,HEBP1,CPT2,EPHX4,UBE2Z,TAF6L,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,PTCHD4,ABCD4,ARHGEF10L,NKAIN3,MAGOHB,LRRC6,DPYSL2,IMPAD1,TSPAN6,PHTF1,DLG1,POF1B,ANKRD12,AKR1B1,KIF22,SUN3,RAB20,RP2,NFU1,ARNT2,TECR,SLC39A10,PTPRE,RASGRP1,OLFML2A,ATL1,TDP1,TRIM8,SOD1,SYNE3,FOPNL,RNF165,ROR1,MRPS18A,PTGFRN,MRPS36,ADRBK2,STK17B,TCN2,SEC14L2,EDNRA,CXXC4,ZNF114,ARHGEF19,NEIL1,FASTKD1,DHRS13,IARS2,TRIM45,ADIPOR1,APBA2,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ELOVL7,ASL,SAMD9,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,EBF4,FXYD5,FNIP1,ZNF692,KNTC1,ACAD8,SIMC1,NCEH1,LRIF1,KDELR1,HP1BP3,OXR1,FBXO8,HMG20B,AMDHD1,EGFR,BCAR3,XKRX,FECH,TSC1,ONECUT1,SLC6A6,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,PROM2,KLF7,ZSWIM5,SPC25,FAM92A1,IL15,SLC2A8,GMPR,TDRKH,MICALL2,LRRC45,SLC25A48,SS18,KCTD15,SETDB2,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,PDIA6,LOXL1,F2R,FRS3,SUSD3,GCA,ZNF525,BAG4,TAF5,SLC39A8,OSTM1,DUSP4,KCTD2,DOCK5,BFSP1,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,CBX4,CCDC24,ANXA3,CDS2,SORT1,POC1B,JKAMP,FRMD6,LRP4,ARMC7,MIER3,AES,TRMT2B,POMGNT1,FAM167A,SAC3D1,ZNF212,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,BRD7,TRIM3,IQGAP3,SYPL1,SUN2,ADAM17,RAB3B,GCLC,DEPDC4,PHLDB3,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MAP1B,KLHL2,C2orf70,HNRNPH2,UBE2D2,TADA2B,OTUB2,ATP6V1C1,GEM,LRRC57,SNPH |
| 5.573e-16 | -35.12 | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP | 195 | 74 | 17758 | 2588 |
ARHGAP11A,CASP3,TXN,SPC25,NDC80,NUF2,KIF2C,MAP1LC3B,STIL,CENPN,PSMD1,IMPAD1,PASK,TAX1BP3,KIF22,HYLS1,MYBL1,CKS2,PLK1,CENPA,FIGNL1,PBK,CDC20,CKAP2L,NUSAP1,AURKB,CDC25C,CDK1,NGFRAP1,KPNA2,SGOL1,CPPED1,KDELC2,DEPDC1,CKAP2,CENPI,CDCA8,KIF23,RACGAP1,CD109,TOP2A,E2F7,NEK2,PRC1,CKS1B,ALDH7A1,BUB1,MXD3,KNTC1,IQGAP3,C12orf75,HMMR,KIF20A,CTNNAL1,ASPM,FHL2,MYBL2,WHSC1,NEURL1B,KIF11,SKA1,SPAG1,PRDX4,FAS,FAM64A,NEIL3,DCUN1D1,FAM83D,AURKA,CENPE,CCNB2,UBE2C,ESPL1,MELK |
| 7.485e-16 | -34.83 | enzyme binding | molecular function | GO:0019899 | 1647 | 360 | 16491 | 2452 |
LAMP1,IBTK,GRIK2,TRIM5,DNAJC3,CUL1,SYTL4,CCNB1,PJA2,SNX9,BARD1,RIC1,PICK1,NCS1,TP73,NPM2,CDKN2C,CALM2,PAK6,CYP1A1,UBE2T,ELMO2,STIM1,ZFP36,IL31RA,DNM2,CRY2,LAMP2,TNIP1,CASP9,PRKAR2B,LDB2,SLC25A5,RNF19B,POR,LCP1,PIAS3,CARHSP1,PLCG1,CAMK2N2,DNM1L,PPP2R4,MAP3K11,NOD2,HDAC1,SERPINB6,ITPKA,ARF6,HSPB1,TRAF5,FGD1,SCN5A,DGKQ,SOX9,PRKAA1,STRN4,CCDC64B,RABGGTA,SH3RF2,TFAP4,CALR,ITGA3,BHLHE41,FBXO7,RANBP1,NEK2,MSH2,SORL1,CD70,MAPK7,PHKG2,C9orf72,PPP6R1,SYTL3,TSPAN33,RIMS2,SOCS5,TRAK2,KIF20A,MAPKAPK3,CALM1,NPC2,EPHA1,ILK,RASA1,CYB5A,PLIN5,FAS,IL1R1,SCARB2,FNTA,PRKAG2,FAM83D,PIAS2,FGD6,AURKA,CABIN1,STK39,MAP3K5,PER3,CBX5,RPS6KA3,TMEM173,DOCK9,EHD1,EGLN1,TPRN,SPRED1,RALBP1,CAST,IQGAP1,NDRG1,WDTC1,PKP2,MAPK4,BCL2L1,PRKACA,GNB2,CCND1,CCNA2,ACAP2,SP100,RALB,DACT1,TNPO2,CDKN1B,DAB2IP,PDE4D,DLG3,FLOT2,CDKN2D,SNX10,NR2C1,MYO5B,DOCK4,FZD4,PFKFB2,UTRN,ATP1B1,SNX12,GABARAPL1,IRS2,PEX5,CCNB3,PPP2R5A,JAK1,CDK19,WFS1,CORO1C,STAT1,TRIOBP,PPP1CB,NRG1,PRIMA1,MLKL,PRKAR1A,PLSCR4,TAOK2,NKX3-1,HSP90B1,BACE1,TRAF2,EPS8,SDC4,FLOT1,PKN1,SPDL1,ETS1,GSTP1,TSPAN17,SNTA1,ANK1,PDCD10,ADD3,CTSC,PTEN,CENPJ,CST3,PRC1,TMBIM6,CITED2,SPRY2,MOB4,PLSCR1,PIK3R1,GRIN1,UBE2A,PARP4,FURIN,DIAPH2,YES1,KIF11,CDK5RAP1,BTG1,TIMP3,ACVRL1,RAB11FIP2,PRDX3,RIN3,NR4A3,HMGA1,ITGAV,FZD5,EXPH5,CASP3,FAF2,EPAS1,CUL4B,SUDS3,UBE2Z,HDAC6,CACNB4,MAP1LC3B,SLC9A3R2,TRIM68,FANCI,PCNA,CTNNB1,CDKL5,P4HB,SHC3,DPYSL2,DLG1,MYRIP,THRB,PLK1,SOD1,EZR,NKAIN1,PRKRA,TYSND1,RHEB,VCP,OPTN,GPRC5B,HOXA9,RAB11FIP1,PRKCDBP,CAB39,KPNA2,ADIPOR1,RAP1GAP,PIFO,RUNX2,PPP1R12A,FXYD3,CALM3,RACGAP1,NCKAP1,CNTNAP2,DOCK11,ADAMTSL4,RB1,NOXA1,TIMP1,PFKL,KCNN4,KIF13B,OCRL,PAK2,EXOC8,CCDC88A,STRADB,RANBP9,EGFR,CDK5R1,MAPKAPK2,NFKBIA,SH3BP4,DCUN1D1,YOD1,ATP1B3,JAK3,TOB1,DRD1,FBXW5,CCNE2,PAX6,SORBS1,FOXM1,TP53,ERBB2,RASGRP3,CCNL1,MICALL2,EMP2,ARHGEF16,SYTL2,RAD23A,PPME1,KIF14,GYS1,NOTCH3,HSPA2,CHP1,SIRT1,BAG4,MBP,TIMP2,TCEB2,AKT1,CDC20,CD40,CDC25C,HSF4,PTGS2,DNAJC10,PTPRJ,ATP1A1,STK38,STAT6,ARHGAP4,SGOL1,ABCA1,CBX4,ZC3HC1,BIN1,GCLM,SORT1,PINK1,TSPAN15,JKAMP,ARHGEF7,RUSC2,SERPINB9,LRP4,SELL,TRIB2,FZD6,SH2D4A,HDAC9,TOP2A,MLPH,LLGL2,UBE2J1,ACTA2,H2AFY,ABCD1,IQGAP3,SYK,MYO5A,HES1,MLEC,PLAUR,PHLDB3,AMFR,RGCC,PPARA,BCAR1,BORA,MAPK8IP1,BCL10,CD8A,SERPINA1,E2F1,ARRB1,PKD2,UBE2C,PKIA,DIS3L |
| 7.686e-16 | -34.80 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP | 542 | 150 | 17758 | 2588 |
CASP3,NDC80,KIF2C,CCNB1,FAM101B,CENPN,PHF1,FANCI,CDKN2C,WEE1,NUP210,UBE2T,SIVA1,OSBPL3,PASK,KIF22,HYLS1,RNF26,MYBL1,PLK1,CENPA,PBK,SERTAD4,CKAP2L,PIF1,AURKB,CCNF,STK17B,CDK1,PRIM1,CDCA4,MAP2,ANKRD6,LIMK1,ZNF367,KPNA2,LASP1,HJURP,SERPINE2,KIF23,RACGAP1,SLC1A3,TSPAN7,IGF1R,NEK2,USP1,LIMCH1,KNTC1,NUP85,SNX7,CYP26B1,KIF20A,CEP89,MYBL2,WHSC1,KIF20B,NFIB,FAM64A,CDCA5,FAM83D,AURKA,CCNB2,CSRP2,CCNE2,ARHGAP11A,SPC25,DLGAP5,CEP70,FOXM1,PTTG1,NUF2,SLC7A2,STIL,MNS1,CCNA2,SMO,PLK4,CKS2,SEPHS1,PPIF,TAF5,PSRC1,FIGNL1,S100A4,PLEKHO1,CDC20,CDCA2,NUSAP1,PKMYT1,DOCK5,CDC25C,PAFAH1B3,JAK1,RBL1,ZNF704,FAM195A,SGOL1,ISOC1,IER5L,DEPDC1,CKAP2,POC1B,CENPI,DCAF7,CIT,BLVRB,ERI2,ERCC6L,CDCA8,CDCA3,NES,H1FX,CKAP5,TOP2A,E2F7,C16orf59,FAM111A,PRC1,CKS1B,BUB1,MXD3,ERBB3,IQGAP3,MSH6,SMC4,DLGAP1,HMMR,SHMT1,MLEC,HMGN5,ASPM,RC3H2,CCDC34,NEURL1B,POLD3,KIF11,SKA1,BORA,DDAH1,CASP7,CDCA7L,E2F1,ETAA1,CENPE,WDR62,NUP37,NCAPG2,UBE2C,ESPL1,MELK |
| 8.299e-16 | -34.73 | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | 592 | 160 | 17758 | 2588 |
TMEM184B,CPT2,HEXB,GATA3,LYNX1,IL18,F11R,GALM,PLA2G16,SLC20A1,SDC1,PDGFB,SLC9A3R2,UBE2T,CNTRL,STIM1,FOSB,CAPG,AOX1,DNM2,AKR1B1,SNX16,TNFRSF18,ACOX2,TINAGL1,S100A13,TUBA4A,CD55,CITED4,PRKRA,ICMT,IDH1,STK17B,SGPP1,PGF,ANKRD10,PIAS3,CARHSP1,HS6ST1,PLEKHG6,WIPI1,GDE1,SH2D3C,SH3GLB2,BMP1,SP6,RBM43,ITPKA,GLCCI1,PPP2R5D,LASP1,ITGA6,DNAJB2,DGKQ,SSX2IP,GNS,RB1,DOPEY2,ZNRF2,ICAM5,VASN,EXOC8,PCYOX1,DAPK1,ACAD8,TTLL1,TSPAN33,EPHX1,MMD,PQLC3,CORO2A,LPGAT1,SPA17,HMG20B,TCF7,NPC2,TP53INP2,PCTP,STX3,FAS,MMP15,FA2H,DGAT2,CDK18,EFNA1,RUSC1,DMPK,SPC25,IL15,NLRX1,ST14,INPP5D,DDIT4L,DGKA,MORC4,RHPN2,COL18A1,KCTD12,TMEM19,DDR1,PDGFA,ATP6V0B,LMO4,SRR,ECE1,TMBIM1,PPIF,PSRC1,UTRN,TRIM7,FZD7,ATP13A2,STAT1,OVOL1,SLC27A1,ENO2,CKAP2,CTSB,ARMC7,GDF15,IFT27,EFNB1,LGALS3BP,DNAJB9,ITGA2B,SAC3D1,RNF128,LLGL2,FDXR,DRAM1,FAM102A,ARVCF,TSPAN13,MXD3,OSGIN1,MSH6,FAH,OPLAH,ARAP2,ALDH2,GUSB,NR4A1,CRIP2,AK4,EMP3,RNPEP,BCAR1,GPLD1,ENDOD1,FUCA1,LDLRAP1,PRCP,FGF18,E2F1,SERPINB5,SH3BGRL2,CENPE,FZD5,LRRC57,DCBLD1 |
| 8.309e-16 | -34.72 | membrane-bounded vesicle | cellular component | GO:0031988 | 3503 | 668 | 17570 | 2579 |
DOC2A,KLK10,IL15RA,DNAJC3,HEXB,FBXO2,TGOLN2,LGI3,IL18,LYNX1,SYTL4,SNX9,CMTM6,LTBP3,GRM5,EPDR1,CALM2,NAPG,PSMD1,AP1M2,TGFBR3,MUC4,ALDH1A3,DNM2,SEMA3G,PPP1CA,TINAGL1,IL10RB,CPE,MGAT5,TUBA4A,VPS11,SH3BGRL,DSTN,RNF11,PRKAR2B,F12,ARF4,LCP1,COL12A1,CARHSP1,DNM1L,ATP7B,MYLK,SERPINB6,ARF6,HSPB1,ANXA11,ALDH6A1,CYP2J2,RAB23,TTYH3,MARCH8,GNS,RAC2,SH3D21,CD22,MEGF8,ATP5H,PCYOX1,CADPS2,MYDGF,NCAM1,PLS1,MEST,GNA11,PSMA4,RHOB,CYB5A,PTPRF,NAAA,SCARB2,NCOA3,SLC4A4,HTT,APMAP,ITPR1,DYSF,MDH1,B4GAT1,MAL2,ARPC2,CFAP20,SERPINB1,TMEM173,RUSC1,MTM1,NQO1,TUBB4B,CD82,MVB12B,PRKACA,APPBP2,MUC16,SCNN1A,CDH1,TAX1BP3,ACSL4,RAB27B,ENPP4,COL6A2,LGALS8,NRBF2,FZD4,SEPT6,SYNE2,CYS1,VPS4B,SYP,RAB38,SNX12,GABARAPL1,ALDH3B1,AXL,PDXK,GEN1,ISOC1,GALK1,TAOK2,HSP90B1,MAN1A2,BACE1,TRAF2,SDC4,FLOT1,PDIA3,CTSZ,PKN1,NUCB2,GSTP1,ICAM1,PDIA4,CAPN2,PDCD10,FUT2,ITGB8,CTSC,GPC3,MGAT4A,CST3,TUBGCP6,BAX,ADAM15,WWP1,IGFBP2,ITM2C,S100A6,PVRL4,PLSCR1,RAPGEF2,DUSP23,GRIN1,PLEKHA7,AK4,BLVRA,FAM109A,CRISPLD2,GALNT3,LDLRAP1,PROM1,RPL12,PLOD2,RAB11FIP2,SYT7,DBI,FAM3C,PLA2G15,ITGAV,CD81,CYBRD1,ACOT7,UNC93B1,BCAM,AGRN,GNPDA1,CUL4B,NDRG2,F11R,GALM,PDGFB,SDC1,SLC9A3R2,SUSD2,CPNE2,PCNA,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,LMAN2L,SLC44A1,ABCA2,NEB,S100A13,SMAGP,THRB,CD55,CR2,EZR,ERP44,IDH1,CDK1,VCP,RHEB,OPTN,DPYSL3,TRIM9,WIPI1,RAB11FIP1,ARRDC1,CTNND1,PIK3C2B,POMT1,MYL12B,PRSS8,BMF,LGALS3,FXYD3,HLA-F,PSMD7,ASAH1,RACGAP1,RAB6A,NCKAP1,FBLN1,ANO1,CORO1B,MYO5C,VASP,TIMP1,RINL,FCHO1,AHCY,TMEM8A,WNT3A,ALDH3A2,CKAP4,PSMA5,ABCC1,C9orf9,PCBP3,SCRIB,MAPKAPK2,EPN3,PVRL2,CSF1,PRPS2,FAM213A,LTBP2,ATP1B3,PLD1,UGP2,CTDSPL,PCBP1,BCAP31,C1orf116,SYTL2,SDF4,PDGFA,ATP6V0B,EFR3A,PLCG2,N4BP3,VAT1,MINPP1,LMAN1,GM2A,DVL2,CTH,CPD,CLCN3,TIMP2,TCEB2,FIGNL1,S100A4,ACO1,MYL12A,DAG1,ATP13A2,RTN4RL1,PTPRJ,ATP1A1,PAFAH1B3,PSMD3,CHMP4B,ANXA9,SYT13,RPL22,LTA4H,ST3GAL1,COPG1,ARFGEF3,CTDSP1,MAN2B2,PACSIN2,GOLIM4,ADGRG1,CD63,TAB3,RUSC2,CTSB,BLVRB,GNAL,GDF15,CRABP2,VPS26A,DNAJB9,FZD6,SIRPA,CDK16,FAM63A,ALDH7A1,SYK,CAMK2G,ATP2B1,FAH,P2RX4,FBLN5,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,COL7A1,CAPNS1,GGH,FXR2,AKAP3,FNDC3A,RNPEP,SCRN2,PRDX4,DDX23,FUCA1,DDAH1,SERPINA1,FAT4,TWSG1,SCG2,TMC5,PGRMC1,PKD2,SH3BGRL2,ACADM,ICOSLG,TBC1D4,SAT2,LAMP1,SUN1,GAA,TXN,HSPG2,ATP8A1,FAM129B,PSME1,NANS,PLXNA1,NCS1,PICK1,STEAP2,SERINC2,AOX1,TACSTD2,MTMR11,PACSIN1,TFG,LAMP2,LOC81691,SNTB2,HSPA12A,MGAM,GALNT7,SLC17A5,MCFD2,SLC25A5,TP53I3,RAB2B,ULK2,AREG,PTER,PPP2R4,BMP1,SERPINI1,RTN3,HLA-E,NDUFA4,APBA1,CALR,DOPEY2,ITGA3,SNX18,ZNRF2,VASN,SORL1,CYSRT1,CD70,OSTF1,CTSD,SYTL3,GPR161,RIMS2,TMED2,GFPT1,QSOX1,KLK5,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,PYGL,VEZT,NPC2,ATP8B3,CYFIP2,PKM,JADE2,ANTXR1,STX3,FAS,AP1AR,APPL2,KLK7,EFNA1,EHD1,PLA2G4A,SLC2A4,GPR107,TRIP10,S100A11,ST14,NDRG1,IQGAP1,BROX,FTH1,KCTD12,CD274,BCL2L1,DDR1,GNB2,EPS8L2,CD46,APLP2,RALB,DAB2IP,EPHB4,LGMN,TSPAN1,SULT2B1,FLOT2,NAGA,TMBIM1,GPX4,SEMA3B,MYO5B,SEC23A,DMTN,CLSTN1,UTRN,ATP1B1,AKR1E2,H2AFV,ALCAM,ZMPSTE24,EPHA10,ACYP1,STK26,PPP1CB,RAB29,B4GALT3,WASF3,PLSCR4,PCOLCE,IGFBP6,EPS8,GPR180,SEPP1,SPR,EFNB1,LGALS3BP,HLA-A,COX7A2,WWP2,MGAT1,FUT8,CD9,SGK3,SLC44A2,TAGLN2,PDGFC,B3GNT2,SHMT1,ALDH2,DENND1B,VAMP3,FURIN,PARP4,C1GALT1C1,UBAC1,YES1,AIF1L,GPLD1,CRTC2,NUCB1,TIMP3,CTNS,ACADSB,FGFR2,PRDX3,RIN3,ABCB1,ERAP1,SERPINB5,GPER1,FZD5,ARSB,OCLN,RGMA,ST13,CRYM,HEBP1,MPP5,TAF6L,ERP29,ECI1,SH3KBP1,EPCAM,RAB15,METTL7A,TSPAN6,DPYSL2,DLG1,CAPG,AKR1B1,RAB20,RP2,MYH14,CTTN,MYRIP,LAMP3,NLRP4,SOD1,ASXL1,LAP3,ITCH,ARHGDIB,TCN2,SEC14L2,ZNF114,GPRC5B,UEVLD,KCNK1,CAB39,GLA,NRGN,APBA2,CPPED1,CAPN1,PCSK5,GRN,LASP1,FAM213B,PIFO,SERPINE2,ASL,ATP6V1E2,CALM3,PM20D2,SPP1,CA2,PFKL,FAM20C,OCRL,COL6A1,PRKCI,HLA-C,SLC12A2,GAD1,SNED1,CCDC88A,SNX7,KDELR1,VWA1,NUBP1,C3orf58,EGFR,MUM1L1,GNAS,INSR,PLPP3,TMEM30A,SH3BP4,RAB31,CTSA,PITPNA,KIF12,SHROOM2,PROM2,PSME2,SLC2A8,HDAC11,SOD2,COL18A1,MRAS,SAYSD1,PHLDA1,EXT2,SMO,GOT1,ECE1,PDIA6,LOXL1,HSPA2,CHP1,EBAG9,GCA,IGSF8,GLO1,CD40,BHLHB9,SECTM1,CANT1,SPTBN5,LIFR,ABCA1,ANXA3,SORT1,ENO2,TSPAN15,SERPINB9,ITGA2B,TMEM63A,KIF5B,MLPH,TAF1B,A4GALT,BMP7,GALNS,ZDHHC13,ACTA2,H2AFY,HSPA13,MYO5A,SYPL1,PGM1,RAB3B,SYBU,NDRG3,ENDOD1,CTSL,HLA-B,GAREM2,RND3,PRCP,DHRS2,CTSV,RAP2C,UBE2D2,UACA,ARRB1,GLB1,ATP6V1C1,PLOD3,LRRC57,CD33 |
| 9.764e-16 | -34.56 | breast-carcinoma-ductal_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductal_carcinoma | 15563 | 2381 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,DNM2,PPP1CA,IL10RB,CPE,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,DMPK,WDR63,MGST2,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,NKX3-1,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,SFXN1,KDSR,HLF,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,KIAA1841,MMD,ZNF84,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,RAB20,SUN3,NFU1,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,OGDHL,LRRC66,MBNL3,SPAG1,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,TFAP4,FLII,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,OSR1,CD81,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,MYO5C,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,SPRED1,REPS2,CAPN12,GPR107,DLGAP5,TCTN2,ST14,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,ZIC5,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,FBXO10,GLT8D2,STX3,DGKH,GABRD,SERTAD2,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.016e-15 | -34.52 | bile_duct | COSMIC cancer mutations | bile_duct | 15891 | 2420 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,RGS14,ARNT,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,GABARAPL1,SPIN3,CCNB3,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,S100A2,TNFRSF19,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,REPS2,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,ZIC5,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.016e-15 | -34.52 | biliary_tract-bile_duct-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-adenocarcinoma | 15891 | 2420 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,RGS14,ARNT,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,GABARAPL1,SPIN3,CCNB3,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,S100A2,TNFRSF19,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,REPS2,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,ZIC5,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.076e-15 | -34.47 | GNF2_CDC20 | MSigDB lists | GNF2_CDC20 | 55 | 34 | 17758 | 2588 |
DLGAP5,FOXM1,PTTG1,CDCA3,NDC80,CDCA8,RACGAP1,KIF2C,TOP2A,PCNA,CCNA2,PRC1,PLK4,CKS1B,BUB1,SMC4,CKS2,PLK1,HMMR,ZWINT,KIF20A,ASPM,CDC20,WHSC1,NUSAP1,AURKB,KIF11,CDK1,AURKA,CENPE,CCNB2,UBE2C,ESPL1,MELK |
| 1.179e-15 | -34.37 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | 778 | 196 | 17758 | 2588 |
HECA,ACVR1,PNISR,IBTK,GNPDA1,XIAP,IL18,F11R,PJA2,MAP1LC3B,SPSB1,PHF1,INPP5E,HSF2,ZFP36,KLF3,PIK3CA,ANKRD12,DUSP10,SNX16,RP2,ARMCX6,WBP4,RCAN3,TIPARP,ING1,CD55,ACBD3,ITCH,CDYL,SLC17A5,RNF19B,LHFPL2,STK17B,POR,OPTN,PGF,ANKRD10,TBC1D17,GPRC5B,KLF12,AREG,WIPI1,KCNK1,P4HA2,RAB11FIP1,ZNF165,KLF11,TANC2,SLC31A2,F2RL1,MAFF,NR2C2,RRAGD,RMND5A,CDK17,LGALS3,CDKN1C,ZNF395,FAM169A,DNAJB2,AKAP17A,C6orf106,RAB6A,DHRS3,DUSP5,PRRG4,BMP2,IGF1R,LYPD3,MAP3K9,PIM1,MAPK7,LRIF1,GPR161,GFPT1,ZNF84,PRRC1,SPTLC2,KDM3A,STX3,RHOB,AP1AR,TSC1,SLCO4A1,NCOA3,SLC6A6,INSR,FNTA,FA2H,ETS2,CSNK1G1,WDR19,NFKBIA,NAB2,FGD6,TMEM159,PER3,TOB1,IRF1,ELK4,PLA2G4A,KIF3C,SORBS1,ARMCX3,UPF3B,GPR107,IL15,NDRG1,SOD2,CCDC68,FTH1,CCNL1,SNN,BAHD1,PHLDA1,TNFSF9,APPBP2,PER2,IER3,NOV,KHNYN,FICD,DOK4,CNNM4,VAT1,CTH,PPIF,SIRT1,CDKN2AIP,MBP,RIPK2,NRBF2,COQ10B,C3orf52,SAT1,VPS4B,DNAJB14,FZD7,GABARAPL1,IRS2,OSBPL2,PTGS2,CDK19,TLE1,KLF5,IRF7,NRG1,ABCA1,GCLM,ARHGEF3,DYRK3,FAM189A2,ARHGEF7,FAM134A,CBLL1,BTN3A1,GDF15,DSE,NFAT5,DNAJB9,ZNF212,SLC25A36,SGPL1,ZFX,CENPJ,PLEKHF1,FAM102A,HSPA13,KLF9,CITED2,CLIP2,SPRY2,ATP2B1,OSGIN1,DUSP1,WBP5,ADAM17,GCLC,EIF5A2,FOS,BSDC1,BTG1,SWAP70,CTNS,RND3,NR1D2,PLA2G15,ARFGAP3,GEM,ZMIZ1,ATP6V1C1,SLC25A38,AHR,HIPK3,GOLGB1 |
| 1.497e-15 | -34.14 | central_nervous_system-brain-glioma | COSMIC cancer mutations | central_nervous_system-brain-glioma | 16286 | 2465 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,IL22RA1,VPS26A,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,GPR107,REPS2,CAPN12,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.931e-15 | -33.88 | regulation of intracellular signal transduction | biological process | GO:1902531 | 1566 | 345 | 16441 | 2455 |
TXN,TRIM24,GRIK2,TRIM5,XIAP,NRG2,GATA3,PSME1,IL18,SEPT4,PJA2,SLC20A1,CARD10,GRM5,TP73,CALM2,DAPK2,PAK6,SESN3,PSMD1,CTGF,RGS3,IL31RA,DNM2,RCAN3,TFG,TIAM1,TNIP1,PBK,ICMT,ARHGEF26,ABR,PLCG1,DNM1L,ANKRD6,PLK2,TBX1,FAM110C,NOD2,MAP3K11,SPRY4,ARF6,UNC5B,HSPB1,TRAF5,F2RL1,STARD13,GAB1,FGD1,NUAK1,SOX9,PRKAA1,NOTCH2,TNFRSF19,KIAA1161,MECOM,RAC2,ITGA3,RALGPS2,CYR61,PIK3AP1,FAM13B,MAP3K9,SORL1,MYDGF,NCAM1,MAPK7,EEF1D,MAPKAPK3,CALM1,SHARPIN,ILK,PSMA4,RHOB,RASA1,FAS,HTT,SEMA4D,PELI2,ITPR1,FAM83D,ARAP1,FGD6,EFNA1,GDF11,MAP3K5,XDH,PLEKHG3,ARHGAP11A,SPRED1,NLRX1,TRIP10,RALBP1,BCL2L1,FLT3,EPS8L2,EPM2A,NOV,ST5,DACT1,DAB2IP,PDE4D,RASGEF1A,CDKN2D,RIPK2,FZD4,PRKCQ,CBL,FZD7,IRS2,FYN,JAK1,WFS1,AXL,SIPA1L1,PLEKHG1,INPP4B,KIAA1804,STAT1,NRG1,RGS14,ARHGEF3,FARP1,NKX3-1,TAOK2,TRAF2,FLOT1,PKN1,GSTP1,ARHGEF40,NFAT5,FGF19,ICAM1,PDCD10,IRAK1,PTEN,MCF2L,BAX,PLEKHF1,TMBIM6,SLC44A2,MAPK11,ERBB3,MAP3K7,SPRY2,TRIM62,FARP2,RASGRF1,ARAP2,ARHGEF28,RAPGEF2,GRIN1,FBXO9,FGFR2,RYK,GRIN2D,GPER1,LRRK1,FZD5,CD81,TNK1,EPHA4,LMCD1,ARFGEF1,NDRG2,NENF,PDGFB,ERP29,SPTB,ARHGEF10L,SIPA1L2,CTNNB1,NPNT,SHC3,ARHGEF37,P4HB,IL6ST,TSPAN6,PSMC2,DLG1,AKR1B1,DUSP10,TNFRSF18,S100A13,RASGRP1,CYP1B1,SOD1,CXXC5,TRIM8,ITCH,EZR,TNFAIP8L1,ARHGDIB,PRKRA,SESN1,CDK1,RHEB,OPTN,PLEKHG6,ARHGEF19,GPRC5B,HPSE,MADD,PRKCDBP,ADIPOR1,RAP1GAP,PSMC1,RRAGD,PRKAA2,BMF,ARAP3,SERPINE2,RASA2,PSMD7,CALM3,SORBS3,RACGAP1,PHLPP1,FBLN1,DUSP5,IL18R1,SSX2IP,BMP2,IGF1R,OCRL,PAK2,FNIP1,MDFIC,ALS2CL,PSMA5,MDFI,SPATA13,STRADB,PDE5A,FBXO8,C3orf58,RANBP9,EGFR,G2E3,CDK5R1,GNAS,MAPKAPK2,TSC1,INSR,CSF1,NFKBIA,SH3BP4,RHOBTB2,JAK3,AVPI1,NF2,IL15,FOXM1,PSME2,TP53,SOD2,P2RX7,ERBB2,RASGRP3,BCAP31,ARHGEF16,PDGFA,KIF14,BCL6,TWIST1,APIP,F2R,DVL2,FRS3,CTH,CHP1,MAP3K3,PPIF,SIRT1,TIMP2,BAG4,AKT1,FIGNL1,S100A4,ERBB2IP,DUSP4,CD40,MAP3K6,DAG1,C3orf33,ARHGAP35,PTGS2,PTPRJ,STK38,PSMD3,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,ARHGAP4,ABCA1,ARFGEF3,PINK1,ADGRG1,TAB3,ARHGEF11,ARHGEF7,PSMD10,TGFBR1,GDF15,TRIB2,AIP,SYDE2,CARD8,ADORA1,BMP7,ZDHHC13,BUB1,IQGAP3,SYK,CAMK2G,MYO5A,DUSP1,P2RX4,HES1,RHOA,PSMB4,PLAUR,RC3H2,LITAF,STMN3,CARD19,AKAP3,MAPK8IP1,BCL10,LEMD2,ARHGAP24,CD8A,BANK1,FGF18,UACA,ARRB1,PKD2,NDFIP1,L1CAM,ARHGEF9,HIPK3,ARHGEF4,NGEF |
| 3.097e-15 | -33.41 | GNF2_CENPE | MSigDB lists | GNF2_CENPE | 40 | 28 | 17758 | 2588 |
HMMR,ZWINT,DLGAP5,FOXM1,ASPM,CDC20,NDC80,CDCA3,MYBL2,CDCA8,WHSC1,NUSAP1,AURKB,CCNF,KIF11,CDK1,PRIM1,PCNA,CCNA2,PRC1,AURKA,CKS1B,BUB1,CENPE,CCNB2,UBE2C,ESPL1,CKS2 |
| 4.729e-15 | -32.99 | single-organism process | biological process | GO:0044699 | 12803 | 2055 | 16441 | 2455 |
HECA,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,SPSB1,SLC35E4,GRM5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,NEK4,UXT,KDELR3,TFAP2C,PNKD,LCP1,ABR,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,PPP6R1,MCCC2,REC8,PYM1,FHL2,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,C5orf30,MAPK4,MGST2,MUC16,ENPP5,TAX1BP3,MYT1,SNX8,RIPK2,AGPS,SEPT6,VPS4B,HTATIP2,SYP,XRCC6BP1,TANC1,NFIX,PDLIM3,SHROOM3,CORO1C,WFS1,AXL,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,DCAF7,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,KLC3,BAX,IGFBP2,ACBD5,PVRL4,TACC1,PIK3R1,MRS2,RAB3IP,PIM3,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,WDR45B,SRSF9,ACOT7,TLL2,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,MGAT5B,SLC9A3R2,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,NFE2L1,CR2,ARFRP1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,KLF11,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,FRAS1,KIF13B,ICAM5,TBCD,SLC30A6,SELK,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,STRADB,PDK3,PRX,CDK5R1,COL13A1,PHLPP2,PLD1,AKIP1,SEMA3A,CCNB2,USP43,HOXB7,TMX4,RHPN2,BCAP31,IER3,KMT5C,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,PTPRJ,IDE,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,DNAJB9,ZDHHC21,FOXP2,UBE2J1,IL17RA,ALDH7A1,CPLX1,TSPAN13,FAM134C,ATP2B1,GCNT1,DUSP1,FBLN5,RHOA,GGH,COL7A1,SCG2,NEIL3,PTGES,HIPK3,ZBTB33,CFAP61,SLC35D2,TXN,SSH1,HSPG2,LGR4,TMEM86B,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,HELZ2,TYMP,OSBPL3,KCNS3,SERINC2,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,SH2D3C,LRIG1,BMP1,SERPINI1,SPRY4,F2RL1,SLC31A2,FGD1,RECQL,CDKN1C,TMEM55B,TXNDC9,C9orf69,DOPEY2,BHLHE41,PPP4R1,MSH2,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,CEP89,ADCK3,DCHS1,PYGL,EPHA1,ATP8B3,MMP15,SLCO4A1,PLEKHH2,PIAS2,APPL2,SFMBT1,KLK7,SAMD8,PER3,EHD1,FOXO6,TCF25,ATP2C2,CYP39A1,EPM2A,NOV,CCNA2,PDE4D,OSBPL7,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,KIF1C,ATP1B1,PYGO1,PKMYT1,ASB13,CBL,B3GALNT2,FZD7,CEP162,ACAD10,NGFRAP1,TRIOBP,CBX7,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,PLD2,FBXO6,SPDL1,FGF19,EFNB1,COX7A2,SLC25A36,RASSF8,E2F7,GNB5,CD9,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,DIAPH2,ARSK,KIF11,CPTP,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,ESPL1,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,EPCAM,ZFYVE16,HSF2,CDKL5,TRPC1,ASH2L,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,MAN2A2,HPSE,KCNK1,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,BVES,ETV5,ABCG2,CALM3,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,SUCO,PRKCI,BRAT1,LIMCH1,C10orf54,GAD1,ETV7,MDFI,SPA17,PDE5A,NUBP1,C3orf58,STEAP1,RANBP9,UAP1,RAB31,NXPH4,CTSA,TOB1,RARG,DYNLRB1,SORBS1,PAX6,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CHP1,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ARHGEF7,TGFBR1,NTAN1,SBF1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MTURN,MYO5A,PGM1,RC3H2,RGCC,TTC7A,LEPR,LEMD2,ARHGAP24,CTSL,CASP7,TRIM69,SPINT2,RAP2C,DTX4,UACA,ARRB1,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,CACNA2D2,SMARCAL1,NRG2,CNTROB,MORF4L2,SYTL4,BARD1,DAPK2,ZYX,AP1M2,TGFBR3,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,DNM1L,MYLK,LSM14B,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,NEK2,STT3B,NDUFA12,KIF20A,SALL4,STAT4,MYBL2,SRSF5,ILK,CYB5A,STK17A,NAAA,NCOA3,MTFMT,SEMA4D,HTT,SETD3,TEX30,ITPR1,AURKA,ALG2,B4GAT1,NDE1,DRP2,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,NUF2,IL13RA1,KTN1,CDS1,CCND1,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,SCN3A,ENPP4,CAMSAP3,FZD4,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,TRABD2A,PDXK,RGS14,ARNT,TNRC6C,TAOK2,NKX3-1,RBM24,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,DTX3L,CAPN2,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,ATXN7L3,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNC93B1,AGRN,GNPDA1,EPHA4,HDAC6,PDGFB,SHC3,ELF5,ANO4,TRAM1,NEB,MCTP1,ERP44,ESYT1,ANLN,CLCN2,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,ASAH1,DOCK11,PGAP1,BMP2,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,TESK1,CORO2A,SPATA13,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,CYP26A1,CDK14,RAD23A,ATP6V0B,GYS1,EGLN3,FAR1,SIRT1,TIMP2,S100A4,CDC20,DUOX1,RTN4RL1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,COPG1,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TRAPPC10,CD63,ADGRG1,DAP,GNE,SWI5,PSMD10,SIRPA,SLC9A2,PPP2R3A,CEP97,BUB1,FAIM,SLC45A3,CAMK2G,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,BANK1,TWSG1,NAT1,TMC5,PGRMC1,PPP2R3C,SPCS3,NDFIP1,UBE2C,CFAP74,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,RIC1,CTGF,ZFP36,IL31RA,STEAP2,AOX1,TFG,RCAN3,XKR8,LAMP2,PBK,CASP9,TNS1,PIF1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,PLK2,PTER,TBX1,NKD1,SARAF,DHTKD1,EIF4EBP2,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,DGKQ,CALB2,ADO,SLC25A27,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,MICB,AMER1,PIP4K2C,CYFIP2,KDM3A,RASA1,FAS,PRKAG2,CSNK1G1,NAB2,SLC4A3,PCDH19,NRBP1,PKD1L2,IRF1,PLA2G4A,ELK4,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,EGR3,NUDT12,GNB2,APLP2,DOK4,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,H2AFV,NIN,OSBPL2,JAK1,STK26,KIAA1804,NRG1,RAB29,B4GALT3,ATMIN,DENND5B,ARHGEF3,PCOLCE,SLC16A14,ARL4C,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,SNTA1,OXCT1,MGAT1,PRC1,SGK3,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,SHMT1,CASK,MPP1,FURIN,VAMP3,C1GALT1C1,RGS9,PRDX3,SLC25A40,PGM2L1,SLC25A38,OCLN,NMRK1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,PTCHD4,SH3KBP1,ABCD4,LRRC6,IMPAD1,TSPAN6,KIF22,SUN3,RAB20,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,PIFO,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,DIAPH2-AS1,EBF4,HP1BP3,PARD3B,GYLTL1B,HMG20B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,PLPP3,NFKBIA,CDCA5,RHOBTB2,ALPK3,YOD1,KIF12,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SLC25A48,SS18,KCTD15,ZDHHC12,FRYL,SMO,GOT1,STEAP3,RPN2,APIP,F2R,LOXL1,SCYL3,FRS3,MAP3K3,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,JKAMP,FRMD6,MDM1,GALNS,CKS1B,BRD7,RAB3B,CENPC,MBNL3,OGDHL,SPAG1,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,IBTK,AK7,GRIK2,SLC25A13,RET,TRAPPC8,BAIAP3,SNX9,LTBP3,CARD10,CDKN2C,NPM2,NAPG,MUC4,CLDN4,CRY2,TMEM37,TIPARP,TIAM1,MGAT5,DSTN,CDA,PRKAR2B,RNF19B,GINS4,ARF4,PLCG1,CARHSP1,ENPP1,ATP7B,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,RABGGTA,TFAP4,FLII,FLRT3,RIMS3,MEGF8,ATP5H,RANBP1,FBXO7,PCYOX1,CADPS2,SLAIN2,MYDGF,ALPK1,MYLIP,ULBP2,DGKG,PHKG2,PAQR7,HPS3,PQLC3,MAPKAPK3,SHARPIN,ERO1A,KIF20B,SFXN5,GNA11,PSMA4,IL1R1,FNTA,CLMN,STK39,CFAP20,CBX5,NUP58,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,INPP5D,PTTG1,APOO,GRK6,MOCS1,RCN1,CDH1,SH3BP1,XYLT2,RASGEF1A,DLG3,LRP11,ETV4,SNX10,MX1,COL6A2,SEC61B,PFKFB2,SAT1,GIGYF1,EBF2,COX20,GABARAPL1,ALDH3B1,SPIN3,CCNB3,PNPLA6,MAPK12,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,SLC25A45,ZFX,PDCD10,ITGB8,FUT2,KNDC1,CST3,RAG1,PARP9,ADAMTS2,OPLAH,PLSCR1,UBE2A,AK4,RGPD5,RPL12,PROM1,LDLRAP1,PLOD2,DBI,NR4A3,SSNA1,ITGAV,OSR1,CMPK2,CD81,PHC1,CCNI,LMCD1,DNAJB11,TEX2,GALM,ITPR2,SPTB,FANCI,CTNNB1,NPNT,ARL1,IL6ST,MITF,SLC44A1,PSMC2,PAPSS1,SCARA3,THRB,PLK1,KCNIP3,CELSR2,CCBL2,EAF2,SESN1,KDM4D,TNS4,HS6ST1,AGPAT2,KPNA2,MYL12B,TC2N,RRAGD,HS6ST3,HJURP,LGALS3,DNAJB2,SLC22A31,PDCL,SORBS3,RAB6A,FBLN1,ANO1,WNT3A,RGMB,MGAT4B,SCRIB,BCL2L13,NMT2,RASGRP2,FOXD2,FA2H,SLC2A6,P4HA3,ZDHHC7,FAM213A,RAD21,TP53,P2RX7,BAHD1,EMP2,STIL,SYTL2,TMSB15B,PDGFA,TTC21B,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,CCSAP,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,STK38,EFNA5,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERCC6L,GDF15,LBR,AIP,NRP2,FZD6,IL22RA1,VPS26A,M6PR,CD109,CDK16,TFAP2A,TRIM21,SGK1,HMGCL,SYK,P2RX4,HES1,GUSB,PLAUR,CRIP2,STMN3,PRICKLE1,MAML2,BBS2,RNPEP,TXNDC11,DGKE,BCL10,CNOT2,DDAH1,FGF18,E2F1,ICOSLG,ARHGEF9,ARHGEF4,LAMP1,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,ZBTB18,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,SEMA6B,MRC2,THEMIS2,DHPS,PRKAA1,AKAP17A,APBA1,HERC6,S100A2,TNFRSF19,TSPAN7,PDXDC1,MESDC2,CALR,RALGPS2,RPL39,DAPK1,DLX4,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,JADE2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,MATN2,ZDHHC20,WDR19,ARAP1,FAM83D,MPP2,CABIN1,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,TCTN2,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,FTH1,BLCAP,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,CD46,RALB,EPHB4,RNASEH2A,TSPAN1,FLOT2,COG2,FOXJ2,RAD17,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,TSPAN18,AREL1,SLC27A3,COBL,PRR15,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,CBLL1,NES,DNAH3,ADGRB2,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,PAPD7,TCFL5,FBXO9,YES1,FOS,CDK5RAP1,CRTC2,TIMP3,ABCB1,FZD5,MELK,UGT8,SLC8B1,ERP29,MAP1LC3B,ECI1,HTR1D,RAB15,SIVA1,CEP78,CTTN,SP5,CERS2,LAMP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,CAB39,GLA,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,TEC,QSOX2,SPP1,B3GALNT1,FAM20C,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,PODXL2,ELK3,VWA1,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,JAK3,SHROOM2,COL16A1,APOL2,DRD1,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,SAP130,CYP4F11,REEP1,ECE1,ETHE1,EBAG9,PTPRU,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,ENO2,ARHGEF11,TSPAN15,SH3D19,CIT,SHPRH,SERPINB9,COL4A5,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,KANK2,SLC35A1,RPGR,B3GALT6,WNT10B,CFAP46,NADK2,RUNX3,FAM73B,NDRG3,FOXL1,CD8A,SWAP70,RND3,CTSV,CSGALNACT1,SLC18B1,MCUR1,PLOD3,CEP41,AHR,ABCG1,CD33,DOC2A,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,IL18,LGI3,KIF26A,CA8,CALM2,TP73,WEE1,RGS12,PSMD1,ARHGAP42,PQLC2,DNAH6,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,VPS11,SPRTN,LOXL2,ICMT,SLC44A3,PGF,LIMK1,MAP3K11,MRPS28,SERPINB6,GAB1,E2F8,HOXC13,NFKBIE,NUAK1,CYP2J2,ZNRF3,MERTK,ELF3,GNS,FAM13B,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,SPTLC2,TP53INP2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,CSRP2,RPS6KA3,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,TUBB4B,GALNT12,WDTC1,PKP2,TESK2,APC2,PRKACA,TNFSF9,ZNF385B,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,PXYLP1,IRS2,SIPA1L1,INPP4B,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ADAM15,ECI2,MAPK11,WWP1,SGCB,CRTAP,S100A6,AMOTL2,CTNNAL1,FMN1,BCL9,GRIN1,FAM109A,NEURL1B,ABLIM2,CRISPLD2,GALNT3,BTG1,KIAA0141,CENPE,HMGA1,NUP37,USF2,FOXA1,MYL9,SIGIRR,CUL4B,NDC80,MCCC1,SUDS3,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,MYBL1,S100A13,ING1,CD55,EZR,C12orf65,KLK6,PRKRA,ZBTB7B,IDH1,CDK1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,PAK2,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,TCF7,IFIT3,SMN1,MAPKAPK2,PVRL2,MFSD2A,ITGA7,PRPS2,LTBP2,TMEM120A,IFI6,RNF146,NIPA1,UPF3B,FOXM1,P3H2,XYLT1,SLC7A2,LPIN3,SDF4,PER2,SRPX,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,EVA1A,MBP,FIGNL1,MYL12A,DNAJC10,PTK7,ADAMTS14,ANXA9,LTA4H,NDST3,POMGNT2,CNEP1R1,GSDMD,MFSD14B,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,SLC35B4,ABCD1,TLE6,FAH,DLGAP1,HMMR,PSMB4,PPARA,TRIM35,CAPNS1,BORA,MAPK8IP1,CD83,PRDX4,SCRN2,FAT4,SERPINA1,NMI,PKD2,ACADM,SUN1,GAA,TAP1,GATA3,PLA2G16,FAM101B,CENPN,CHST2,NCS1,ELMO2,ATRNL1,PACSIN1,ORAI2,KIFC2,MGAM,AGO4,AURKB,SAV1,MCFD2,ZFAND5,SLC25A5,TP53I3,ULK2,SGPP1,SLC25A4,AREG,GNPTAB,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,ITGA3,PIK3AP1,CYR61,SLC16A6,BDH1,SORL1,TNFRSF12A,CD70,RIMS2,TSPAN33,IGSF3,QSOX1,FADS2,MFI2,B9D2,PTPRH,ANO6,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,IRX4,CD274,AIFM2,MNS1,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CAPN6,TMEM43,DMTN,COX11,SLC11A2,AKR1E2,CMTM7,EPHA10,FYN,PPP2R5A,STAT1,PPP1CB,KLF5,SLC27A1,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CYB561,SPR,SEPP1,SIX4,LGALS3BP,RND1,PTEN,PPP1R10,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,PARP4,GPLD1,CTNS,SERPINB5,GRIN2D,GPER1,ARSB,NCAPG2,JARID2,USP16,ESYT2,EXPH5,CASP3,LTBP1,EMX1,CPT2,EPHX4,KIF2C,DNER,CHPF,ZCCHC12,GRHL1,DPYSL2,CAPG,DLG1,AKR1B1,ARNT2,RP2,TECR,SLC39A10,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,STRIP2,RNF165,MRPS18A,MRPS36,STK17B,NEIL1,FASTKD1,DHRS13,ADIPOR1,APBA2,PSMC1,GRN,FAM213B,ELOVL7,ATP6V1E2,CA2,LRRN2,FXYD5,FNIP1,KNTC1,NCEH1,ACAD8,KDELR1,OXR1,BTN3A2,AMDHD1,BCAR3,NUDT16,SLC6A6,UTP14C,PAPD5,CGREF1,PITPNA,EGFL7,FBXW5,KLF7,GAS2L1,SLC25A24,IL15,PSME2,SLC2A8,GMPR,MICALL2,SVBP,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,AP5M1,DUSP4,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CYP2U1,PLXND1,SGOL1,REEP4,LIFR,ANXA3,POC1B,LRP4,AES,NOTUM,POMGNT1,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,IQGAP3,SYPL1,SUN2,ADAM17,GCLC,NR4A1,DEPDC4,ASPM,POLD3,MAP1B,HLA-B,MARC1,PRCP,DHRS2,TADA2B,UBE2D2,HOXB13,GEM |
| 5.191e-15 | -32.89 | HALLMARK_TNFA_SIGNALING_VIA_NFKB | MSigDB lists | HALLMARK_TNFA_SIGNALING_VIA_NFKB | 198 | 73 | 17758 | 2588 |
IL15RA,TRIP10,TAP1,SOD2,IL18,EGR3,CCNL1,SNN,PHLDA1,SPSB1,TNFSF9,MXD1,IER3,CCND1,BTG3,ZFP36,IL6ST,FOSB,BCL6,NFKB2,PTPRE,TIPARP,TNIP1,RIPK2,SAT1,PTGER4,DUSP4,RNF19B,SOCS3,IRS2,PTGS2,AREG,PLK2,F2RL1,MAFF,ABCA1,DDX58,KLF2,NFKBIE,SDC4,NFAT5,DUSP5,ICAM1,BMP2,CYR61,SLC16A6,FJX1,DRAM1,SGK1,KLF9,ATP2B1,DUSP1,TGIF1,HES1,NR4A1,PLAUR,LITAF,FOS,RHOB,CD83,BTG1,ETS2,CSF1,NFKBIA,SLC2A6,NR4A3,NR4A2,EFNA1,GEM,ICOSLG,IFIH1,IRF1,EHD1 |
| 5.677e-15 | -32.80 | organelle membrane | cellular component | GO:0031090 | 3010 | 583 | 17570 | 2579 |
DOC2A,ACACB,IL15RA,MRPS15,SLC25A13,DNAJC3,PNPLA2,RET,FBXO2,SYTL4,SNX9,NAPG,PQLC2,AP1M2,CABP1,CYP2S1,RDH14,FUT1,DNM2,CPE,MGAT5,ERAP2,VPS11,KDELR3,PRKAR2B,ICMT,CYP4F3,ENPP1,WDR11,DNM1L,ATP7B,MRPS28,ARF6,STARD13,FAM169A,GGA1,SEC61G,CYP2J2,RAB23,SLC36A4,COX6C,FAM21C,LMNA,MARCH8,RAC2,FLRT3,ATP5H,PCYOX1,CADPS2,STT3B,CNGA1,NCAM1,MOXD1,NDUFA12,PPP6R1,NUP85,EPHX1,NAGPA,UFD1L,ERO1A,MEST,SPTLC2,GOLT1A,SFXN5,GNA11,RHOB,CYB5A,SCARB2,TIMM8A,HTT,ITPR1,DGAT2,DYSF,ALG2,B4GAT1,NUP58,TMEM173,DMPK,CCDC109B,LFNG,GALNT12,APOO,MGST2,MVB12B,APC2,KTN1,APPBP2,CDS1,SCNN1A,XYLT2,ACSL4,RAB27B,SNX10,TMEM9,MX1,SNX8,SEC61B,ERMP1,FZD4,AGPS,SYNE2,CYS1,VPS4B,SYP,PXYLP1,RAB38,DNAJB14,COX20,GABARAPL1,PEX5,STX10,SLC9A6,WFS1,PNPLA6,TRABD2A,SLC25A30,TTC8,TAOK2,HSP90B1,TRAF2,MAN1A2,BACE1,BIK,FLOT1,CTSZ,SLC25A43,SGPL1,SLC25A45,PDCD10,IRAK1,FUT2,CTSC,ALG13,MGAT4A,FAM20B,CST3,BAX,TMBIM6,PLEKHF1,ITM2C,TPCN1,TMX1,MOB4,ACBD5,ELOVL3,EIF5A2,MRS2,GALNT3,PROM1,LDLRAP1,PLOD2,SYT7,RAB11FIP2,SLC35B3,ARFGAP3,WDR45B,UNC93B1,EPHA4,MCCC1,ARFGEF1,ITPR2,MGAT5B,CDIPT,PIGL,PDGFB,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,LMAN2L,ARL1,SLC44A1,ABCA2,PXMP4,SCARA3,TRAM1,SMAGP,NFE2L1,KLK6,ERP44,ESYT1,VCP,RHEB,OPTN,HS6ST1,AGPAT2,WIPI1,DOLPP1,RAB11FIP1,TTC9,PIEZO1,POMT1,RRAGD,BMF,LMTK3,LGALS3,FXYD3,HLA-F,RAB6A,B4GALT4,DHRS3,PGAP1,B4GALNT1,SLC30A6,SELK,TMEM8A,WNT3A,FAR2,MPHOSPH9,ALDH3A2,CKAP4,CHSY3,CYP26B1,MRPS33,MGAT4B,EMC2,BCL2L13,ZDHHC3,C18orf8,MOSPD3,COQ10A,FA2H,MFSD2A,PHLPP2,ZDHHC7,PLD1,TMEM120A,XYLT1,P2RX7,ERBB2,FAM198B,LPIN3,EMP2,BCAP31,CYP26A1,PDGFA,ATP6V0B,WDR44,N4BP3,VAT1,NOTCH3,LMAN1,FAR1,PPIF,SIRT1,CLCN3,EVA1A,COQ10B,ATP13A2,TAPBP,PTGS2,MAOA,IRF7,CHMP4B,ST3GAL1,AIFM3,NDST3,POMGNT2,CNEP1R1,ZC3HC1,COPG1,FAM134B,ARFGEF3,MAN2B2,PINK1,PACSIN2,GOLIM4,TRAPPC10,TAB3,CD63,SCD5,DSE,LBR,FZD6,VPS26A,PARM1,DNAJB9,M6PR,ZDHHC21,SLC35B4,UBE2J1,SGK1,ABCD1,HMGCL,CAMK2G,GCNT1,P2RX4,RHOA,MLEC,IFITM3,PLAUR,AMFR,LITAF,PRICKLE1,COL7A1,CARD19,FNDC3A,BBS2,TXNDC11,MAPK8IP1,SERPINA1,PGRMC1,PKD2,SPCS3,NDFIP1,TBC1D4,PTGES,GOLGB1,LAMP1,SUN1,SLC35D2,GAA,ATP8A1,TAP1,PJA2,NCS1,CHST2,PICK1,SLC9A7,CYP1A1,STIM1,OSBPL3,STEAP2,SNX16,MARCH2,PACSIN1,TFG,LAMP2,SPATA18,SNTB2,BNIP3L,SLC35C1,KIF13A,SLC17A5,GALNT7,MCFD2,SLC25A5,POR,ULK2,RAB2B,SGPP1,SFXN1,KDSR,SLC25A4,AREG,GNPTAB,SARAF,RTN3,MRPL44,SCOC,HLA-E,TMEM55B,SLC25A27,NDUFA4,NOTCH2,SLC1A3,KIAA1161,CALR,DOPEY2,SNX18,ZNRF2,NECAB3,VASN,BDH1,TPST1,PIKFYVE,GPR161,TMED2,FAM69A,PIGC,QSOX1,FADS2,PRODH,PMPCB,B3GNT7,MMD,LPGAT1,ATP8B3,ANTXR1,DGKH,FAAH,APPL2,ARAP1,SAMD8,MAP3K5,PLIN3,EHD1,PLA2G4A,SLC2A4,ARMCX3,CEP70,TCTN2,NLRX1,NDRG1,ATP2C2,BCL2L1,SNN,AIFM2,CYP39A1,GNB2,SLC25A35,ZFYVE9,CD46,ACAP2,TNPO2,TSPAN1,FLOT2,TMBIM1,GPX4,MYO5B,SEC23A,TMEM43,COG2,DMTN,CLSTN1,COX11,SLC11A2,PKMYT1,B3GALNT2,ITPR3,TRIQK,ATP10D,ZMPSTE24,DDOST,STK26,SLC27A1,HS3ST3B1,B4GALT3,SLC27A3,NR3C2,MRPS9,ATP9A,PLD2,COX7A2,HLA-A,SLC25A36,AKIRIN1,MGAT1,FUT8,CD9,DRAM1,SLC44A2,MAP3K7,PDGFC,CASK,B3GNT2,VAMP3,FURIN,C1GALT1C1,CPTP,GPLD1,NUCB1,CTNS,SLC25A40,ERAP1,GPER1,FZD5,SLC25A38,ESYT2,FAF2,CPT2,MAP1LC3B,SLC8B1,ECI1,SH3KBP1,CHPF,ABCD4,ZFYVE16,RAB15,DLG1,RAB20,TECR,MYRIP,RASGRP1,CYP1B1,LAMP3,CERS2,ATL1,SYNE3,ACBD3,MRPS18A,MRPS36,PTGFRN,MAN2A2,HPSE,GPRC5B,NRGN,RAP1GAP,CHPT1,STARD3NL,PEX6,ELOVL7,ABCG2,QSOX2,B3GALNT1,OCRL,COL6A1,PRKCI,SUCO,HLA-C,GAD1,KDELR1,SNX7,GYLTL1B,STEAP1,C3orf58,EGFR,GLCE,GNAS,FECH,INSR,PLPP3,TMEM30A,RAB31,CTSA,APOL2,PROM2,DRD1,SLC25A24,SLC2A8,PDIA5,SAYSD1,PHLDA1,EXT2,SLC25A48,COX14,CYP4F11,REEP1,SMO,RPN2,STEAP3,ECE1,PDIA6,CHP1,EBAG9,SEPHS1,SOAT1,KREMEN2,OSTM1,SLC39A8,C3orf52,AP5M1,MRPS35,ERBB2IP,TMTC2,CASP4,PEX2,CANT1,SPTBN5,CYP2U1,REEP4,ANXA3,CDS2,SORT1,JKAMP,POMGNT1,ITGA2B,TMEM63A,SNX13,A4GALT,RRBP1,KIAA0319,ZDHHC13,SLC35A1,B3GALT6,SYPL1,SUN2,RAB3B,NR4A1,SYBU,MPV17L2,LEMD2,HLA-B,MARC1,RND3,RAP2C,CSGALNACT1,ARRB1,MCUR1,ATP6V1C1,PLOD3,ABCG1 |
| 7.909e-15 | -32.47 | lymphoid_neoplasm | COSMIC cancer mutations | lymphoid_neoplasm | 12854 | 2028 | 17775 | 2585 |
HECA,FAM160B1,IBTK,GRIK2,AK7,SLC25A13,PNPLA2,RET,MCOLN3,CCNO,TRAPPC8,BAIAP3,DPP8,SNX9,FAM46C,SPSB1,CMTM6,CARD10,LTBP3,SLC35E4,GRM5,CDKN2C,NAPG,MUC4,PAQR5,ATP13A3,DNM2,PPP1CA,TMEM37,TIAM1,IL10RB,TIPARP,CPE,ANKRD9,MGAT5,DNAAF3,NEK4,FBXL16,DSTN,CDA,TMEM98,TFAP2C,PRKAR2B,RNF19B,PNKD,GINS4,LCP1,ABR,ENPP1,BOLA3,PLCG1,MPRIP,CELF5,ATP7B,FAM114A1,TRAF3IP1,NOD2,HDAC1,RNASEL,STARD13,ANXA11,ZNF720,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,CCDC64B,FAM21C,RABGGTA,ATG4A,MARCH8,TFAP4,FLII,SH3D21,RAC2,ZCCHC17,FRY,PAIP2B,MEGF8,RIMS3,FBXO7,RANBP1,FBXL14,MAP3K9,SLAIN2,USP38,CADPS2,FAM84B,ALPK1,CNGA1,ZMYM1,MAPK7,MOXD1,DGKG,MYLIP,KANK3,NUP85,PHKG2,PPP6R1,TTLL1,MCCC2,HPS3,PQLC3,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,GNA11,SFXN5,PLIN5,MAGED2,IL1R1,CACHD1,FNTA,SLC4A4,ETS2,DGAT2,CLMN,OSCP1,GDF11,CBX5,TMEM173,ADAMTS16,DOCK9,WDR63,DMPK,TPRN,NQO1,LFNG,RHBDL3,APOO,GRK6,MGST2,FAM91A1,MOCS1,REPS1,APPBP2,KIAA1147,RCN1,RBM23,ST5,MUC16,CDH1,SH3BP1,XYLT2,LRP11,RASGEF1A,MYT1,SNX10,MX1,TMCC2,SNX8,COL6A2,RIPK2,AGPS,PFKFB2,PTPN9,SEPT6,SAT1,VPS4B,HTATIP2,DNAJB14,TANC1,ZNF618,EBF2,GIGYF1,GABARAPL1,SPIN3,PDLIM3,CCNB3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,FAM149A,DMWD,PRIMA1,SLC25A30,ISOC1,MAPK12,MZT1,MPZL1,FAM189A2,CKAP2,BACE1,TRAF2,BIK,CCM2,HABP4,SDC4,OSGIN2,FLOT1,BTN3A1,PLPPR4,ZNF219,SLC25A43,NFAT5,BEX2,CTNNBIP1,DIRAS3,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,IGSF9,KNDC1,MGAT4A,FAM20B,TUBGCP6,KLC3,FAM102A,IGFBP2,RAG1,CASD1,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,PIK3R1,MRS2,UBE2A,CXorf57,AK4,RAB3IP,C4orf27,CNTNAP1,LDLRAP1,RPL12,PROM1,PLOD2,RAB11FIP2,SYT7,SLC35B3,FAM3C,PPM1H,FBXO44,ITGAV,CMPK2,ACOT7,PHC1,TLL2,TMEM131,CCNI,ILDR1,BCAM,TNK1,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,NENF,ITPR2,GALM,MGAT5B,SPTB,TFAP2E,PLS3,INPP5E,BTG3,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,P4HB,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,TMEM143,ABCA2,NTN4,SMAGP,PLK1,KRT80,THRB,KCNIP3,PTPN18,MARK1,CELSR2,NFE2L1,CR2,CCBL2,CKAP2L,ARFRP1,NKAIN1,EAF2,SESN1,TRUB1,DZIP1L,TRIM9,HS6ST1,PLEKHG6,TRAM2,PI4K2B,KCNMB4,AGPAT2,KLF12,ZNF367,ARRDC1,KLF11,TTC39C,TC2N,HS6ST3,RRAGD,PARP12,USH1C,DNAJB2,FXYD3,SORBS3,ADCK5,RAB6A,NCKAP1,FBLN1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,ICAM5,FCHO1,AHCY,PIM1,FAR2,WNT3A,NTN1,MPHOSPH9,DPYSL5,PLEKHA6,PCDH1,USP31,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,PDK3,BCL2L13,PRX,NMT2,C18orf8,CDK5R1,RASGRP2,FA2H,COL13A1,PHLPP2,KBTBD2,P4HA3,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CDAN1,USP43,RAD21,CTDSPL,TMX4,TP53,P2RX7,RHPN2,PRR7,STIL,PCBP1,SYTL2,TTC21B,PDGFA,WDR44,TACC2,LMO4,PPME1,BCL6,PLK4,ZDHHC23,CDH3,ESPN,GLB1L2,NOTCH3,OAS3,LMAN1,SULF2,PPIF,CLCN3,ERLEC1,AKT1,ACO1,DAG1,ATP13A2,PTGS2,TAPBP,PTPRJ,IDE,PAFAH1B3,RBL1,ABHD12,STK38,MAOA,XRCC3,CHMP4B,EFNA5,IRF7,SYT13,ARHGAP4,BTBD6,ST3GAL1,FAM134B,BIN1,CMAS,PINK1,DYRK3,CPEB4,CDH22,TAB3,KLHL13,CTSB,SCD5,HAL,GNAL,MCTP2,CDCA8,ERCC6L,HMGN3,LBR,AIP,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,CDK16,LYPD6,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,IL17RA,ALDH7A1,CPLX1,SYK,FAM134C,ATP2B1,LRRC24,DUSP1,NFE2L3,P2RX4,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,DPP9,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,USP6,BCL10,DDX23,CNOT2,DDAH1,SCG2,NEIL3,FGF18,E2F1,SH3BGRL2,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,FAM171B,SLC35D2,TXN,PNISR,SSH1,HSPG2,LGR4,VANGL1,TMEM86B,TSC22D3,CUL1,C1orf198,PSME1,PDGFRL,CAMK1D,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,ZNF823,STIM1,OSBPL3,FOSB,POLL,KCNS3,SERINC2,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,METAP2,SPATA18,ACVR1C,CDYL,BNIP3L,SLC35C1,KIF13A,LDB2,POR,RAB2B,PRIM1,ANKRD10,GDE1,SH2D3C,LRIG1,PRDM5,BMP1,MAPK13,SERPINI1,NFKBIZ,SPRY4,WBSCR27,SLC31A2,CCDC97,FGD1,RECQL,MRC2,CDKN1C,SCOC,TBC1D1,PRKAA1,AKAP17A,TXNDC9,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,SH3RF2,CALR,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,AIM1,MSH2,TPST1,DAPK1,ADCK2,PRKG1,TMEM51,OSTF1,CACNA1D,ZNF117,SYTL3,KCTD3,GPR161,TRAK2,SPATA20,GFPT1,GCC2,PRODH,KCNJ12,KLK5,CEP89,ADCK3,LPGAT1,DCHS1,WHSC1,PYGL,ATP8B3,ANTXR1,NFIB,PDE11A,MMP15,SLCO4A1,AP1AR,NT5C2,PLEKHH2,TJP3,FAAH,PELI2,C1orf21,MATN2,PIAS2,FAM83D,MPP2,APPL2,ARAP1,SFMBT1,CABIN1,CDK18,PLIN3,PER3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,KIF3C,TCF25,DLGAP5,TCTN2,REPS2,CAPN12,GPR107,ST14,CERCAM,RALBP1,NDRG1,CCDC110,ATP2C2,FAM78A,FTH1,TMEM170B,TMEM19,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPS8L2,EPM2A,CD46,NOV,CCNA2,ACAP2,TRANK1,RALB,BRI3,RNASEH2A,PDE4D,EPHB4,FLOT2,MED30,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,CLSTN1,TMEM144,KIF1C,ATP1B1,PKMYT1,PYGO1,B3GALNT2,CBL,ASB13,ITPR3,ALCAM,ATP10D,AMZ2,POPDC3,ACAD10,HAGHL,TRIOBP,ZNF704,FAM195A,PRR15,COBL,MAMDC2,PRKAR1A,PLSCR4,DEPDC1,IGFBP6,HAPLN3,SLC41A1,CENPI,EPS8,NES,CBLL1,PBX3,EFHD2,HERC5,PLD2,DNAH3,FGF19,HLA-A,WWP2,SCML1,SLC25A36,CKAP5,RASSF8,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,CITED2,MSH6,FARP2,PDGFC,ZWINT,ARHGEF28,B3GNT2,LONRF3,PAPD7,ZC3H11A,DIAPH2,FBXO9,C2orf69,UBAC1,YES1,GRTP1,ARSK,KIF11,CRTC2,DCTN6,ACADSB,DGCR2,SEC14L4,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR62,WDR91,ESPL1,CXorf56,DEF6,MELK,RGMA,FAF2,UGT8,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,ERP29,ECI1,TRIM68,HTR1D,EPCAM,ZFYVE16,ADPRHL1,SIPA1L2,RAB15,HSF2,METTL7A,ARHGEF37,CASC4,CDKL5,ANKFN1,TRPC1,ASH2L,CTTN,MYRIP,BTBD3,IL1RAP,STK35,LAMP3,NLRP4,ASXL1,LAP3,ITCH,ACBD3,RGAG1,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SP6,GLA,RBM43,CHPT1,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,SERPINE2,ZNF395,PPP1R12A,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,DUSP5,QSOX2,TYW3,SPP1,CES2,FAM20C,PFKL,OCRL,COL6A1,MTMR10,PRKCI,SRP54,BRAT1,LIMCH1,NPTN,HLA-C,C10orf54,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNED1,SNX7,MDFI,ELK3,PODXL2,SPA17,PDE5A,VWA1,KIAA1109,HEATR5A,PRRC1,NUBP1,PDIK1L,C3orf58,STEAP1,RANBP9,MFSD7,RHPN1,SOX13,INSR,UAP1,TMEM30A,SH3BP4,SPAG7,RAB31,DCUN1D1,NXPH4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,RARG,SNX30,DRD1,LMO7,LZTFL1,DYNLRB1,NCKAP5,SORBS1,PAX6,HDAC11,SOD2,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,EXT2,KCTD9,MXD1,SAP130,ZNF687,CYP4F11,KIF14,REEP1,FABP6,ZBTB49,DIXDC1,ECE1,EPB41L4B,NFKB2,ETHE1,UPF3A,EBAG9,CKS2,SEPHS1,SOAT1,RFK,PTPRU,BTBD19,MRPS35,CD40,TMTC2,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,ALDH5A1,STAT6,TLE1,SPTBN5,RCAN2,ABCA1,LNP1,KDELC2,GLIS3,FBLIM1,ENO2,TSPAN15,ARHGEF11,SHPRH,SH3D19,ARHGEF7,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,RBP7,XPR1,HMGXB4,ITGA2B,HDAC9,TMEM63A,KIF5B,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,TOX2,RRBP1,ACTA2,ARVCF,H2AFY,KANK2,CLIP2,C12orf75,RPGR,SLC35A1,RBMS2,MYO5A,PGM1,PHF20L1,WNT10B,RC3H2,SYBU,TTC7A,RUNX3,NDRG3,FOXL1,LEPR,LEMD2,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,RND3,TRIM69,SPINT2,FIBCD1,RAP2C,CSGALNACT1,UACA,ARRB1,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,DOC2A,ACACB,KLK10,TRIM24,ADD1,IL15RA,AASS,DNAJC3,CACNA2D2,SMARCAL1,MMADHC,XIAP,DHX8,NRG2,LGI3,LYNX1,CNTROB,MORF4L2,SYTL4,CA8,BARD1,KIF26A,PHF1,EPDR1,TP73,CALM2,DAPK2,WEE1,ZYX,ARHGAP42,PQLC2,PSMD1,AP1M2,TGFBR3,RGS12,KIAA1107,DNAH6,CABP1,CYP2S1,PPP1R16A,ALDH1A3,SLC46A1,RDH14,FUT1,SEMA3G,ACOX2,PIK3CD,ODF2L,APOBEC3G,ERAP2,TUBA4A,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,RNF11,LOXL2,F12,ICMT,PPP1R14C,MYOM1,COL12A1,SLC44A3,TRIM47,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,RELL1,ARF6,PDPR,GAB1,NFKBIE,FAM169A,TMTC3,CYP2J2,SOX9,STRN4,SLC36A4,ZNRF3,MERTK,LMNA,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,ZIC5,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SPTLC2,RHOB,DCP2,CYB5A,STK17A,DHX32,PTPRF,NAAA,NCOA3,SCARB2,MTFMT,SEMA4D,HTT,SETD3,ITPR1,OSMR,AURKA,DYSF,FBXO27,NDE1,DRP2,ARPC2,TRPC3,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,TMSB15A,GALNT12,ACTR8,ETNK1,RGS20,WDTC1,PKP2,TESK2,PRSS22,IL13RA1,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,CDS1,CCND1,SCNN1A,RNF220,SP100,RTKN2,ARL4D,TMEM9,RNF169,SCN3A,ENPP4,CAMSAP3,SSH3,LGALS8,NRBF2,PLEKHO1,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,PEX5,TTC12,SLC9A6,WWTR1,SIPA1L1,PLEKHG1,INPP4B,PDXK,RGS14,ARNT,TTC8,GALK1,FARP1,TAOK2,TNRC6C,PARP14,PLEKHJ1,MAN1A2,RASSF7,PDIA3,ANO9,PKN1,NUCB2,KCNC4,ETS1,TSPAN17,SRPX2,HOXB2,ICAM1,NEO1,PDIA4,DTX3L,CAPN2,CXCL16,ANK1,ADD3,SLC27A6,IRAK1,CTSC,ARSG,FAM160A2,ANKS1B,KCNK5,ALG13,CALD1,ECI2,ADAM15,WWP1,ZNF230,MAPK11,NPTXR,SGCB,ITM2C,TPCN1,TMX1,HCN3,POU6F1,AMOTL2,LCA5,FAM160A1,FMN1,CTNNAL1,BCL9,RAPGEF2,MFSD2B,EIF5A2,GRIN1,PLEKHA7,BLVRA,FAM109A,NEURL1B,SNTB1,CRISPLD2,ABLIM2,TXK,GALNT3,DCAF10,PITX2,BTG1,KIAA0141,CCDC6,ATXN7L3,ACVRL1,NR1D2,ZFP30,ARFGAP3,FHL1,CENPE,NUP37,SHOX2,USF2,CYBRD1,DCBLD1,FOXA1,UNKL,AGRN,GNPDA1,CUL4B,EPHA4,FHDC1,MCCC1,NDC80,CDIPT,PDGFB,SDC1,PIGL,SHC3,MKRN3,DDHD2,ELF5,DUSP10,TNFRSF18,RGS5,TLN2,ANO4,TRAM1,MYBL1,DDX59,NEB,S100A13,CCDC38,ZNF462,PCGF5,CD55,ING1,MCTP1,C12orf65,EZR,ERP44,KLK6,ESYT1,FAM212B,ANLN,IDH1,CLCN2,ZBTB7B,LHFPL2,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,PLCH1,MFAP3L,TBC1D17,CDCA4,MAP2,WIPI1,P4HA2,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,PRKAA2,FAM89A,BMF,HLA-F,ZCCHC24,UBASH3B,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,C3orf18,IL18R1,PGAP1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,KIAA0895,IGF1R,GATA2,EXOC8,MDFIC,TMEM8A,PLCB2,ALDH3A2,PSMA5,ABCC1,C9orf9,CYP26B1,CHSY3,MRPS33,WDR72,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,TCF7,IFIT3,UNC45B,ANKRD29,ZDHHC3,MAPKAPK2,EPN3,DHDH,PVRL2,ITGA7,CSF1,MFSD2A,PRPS2,LTBP2,ATP1B3,CTBP1,NIPA1,FAM45A,KCNAB3,NF2,UGP2,UPF3B,FOXM1,XYLT1,ZNF28,CCDC68,ERBB2,SLC7A2,FAM198B,LPIN3,KBTBD11,C1orf116,SDF4,PER2,CDK14,SRPX,EFR3A,PLCG2,N4BP3,GYS1,SCN2A,MINPP1,EGLN3,FAR1,CTH,CPD,SIRT1,TMTC1,MBP,COQ10B,MYPOP,DNAJC10,DUOX1,RTN4RL1,ATP1A1,PSMD3,PTK7,ADAMTS14,ANXA9,ZBTB6,RPL22,AIFM3,LTA4H,ZNF701,NDST3,CMTM4,ZC3HC1,MAN2B2,GSDMD,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,DAP,RUSC2,BLVRB,GNE,GABRG2,PSMD10,SELL,CHAC2,JAG2,DSE,PPP2R3A,SLC9A2,CCDC92,CEP97,MAGEE1,SLC35B4,BUB1,ABCD1,KLF9,FAIM,SLC45A3,CAMK2G,TLE6,FAH,IGDCC4,HMMR,DLGAP1,MLEC,PSMB4,NR3C1,IFITM3,AMFR,LITAF,PPARA,CAPNS1,TRIM35,PELI3,AKAP3,FNDC3A,BCAR1,NPDC1,MAPK8IP1,PRDX4,CD83,FUCA1,TMEM50B,BANK1,FAT4,SERPINA1,NAT1,ZNF214,CDCA7L,TMC5,NETO2,PGRMC1,FAM117A,CLIP4,PPP2R3C,PKD2,ACADM,NDFIP1,TBC1D4,SAT2,DIS3L,SUN1,GAA,PPP4R4,ACVR1,TMEM41B,FAM129B,ATP8A1,KLC2,TAP1,PPFIBP2,GATA3,PLXNA1,CCNB1,PLA2G16,SLC20A1,ELMOD2,NCS1,CHST2,SESN3,CTGF,ELMO2,PRICKLE3,IQCE,ZFP36,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,RCAN3,TFG,PACSIN1,XKR8,ORAI2,LOC81691,KIFC2,SNTB2,PBK,HSPA12A,CASP9,NBPF3,TNS1,GALNT7,AURKB,CCNF,MCFD2,SAV1,SLC25A5,TP53I3,SPNS3,ARHGEF26,ULK2,SGPP1,AHRR,SFXN1,RBM47,PLK2,GNPTAB,NKD1,DHTKD1,EIF4EBP2,UNC5B,TANC2,TRAF5,RTN3,LZTS1,DLAT,DDX58,KLF2,CDK17,MRPL44,INPPL1,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,ISYNA1,SLC1A3,NOTCH2,KIAA1161,BMP2K,PRRG4,MECOM,ITGA3,SNX18,PIK3AP1,SLC16A6,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,TSPAN33,RIMS2,EEF1D,IGSF3,DNAI1,FAM69A,EPB41L5,FADS2,PMPCB,DDB2,QSOX1,B3GNT7,KIAA1841,MFI2,TBC1D8B,MICB,AMER1,ANO6,PTPRH,PIP4K2C,KCTD20,KDM3A,FBXO10,GLT8D2,RASA1,STX3,FRMD4B,FAS,DGKH,SERTAD2,PRKAG2,TMEM54,ISM1,DCK,TCEAL4,SLC4A3,FGD6,PCDH19,MAP3K5,NRBP1,PKD1L2,IRF1,PLA2G4A,PLEKHG3,FRMPD3,SLC2A4,CEP70,NLRX1,TMEM217,TRIP10,S100A11,RPS6KA1,IQGAP1,SUZ12,CAST,IRX4,RNF182,CD274,NUDT12,MNS1,GNB2,TMPRSS4,SLC25A35,CYHR1,APLP2,ZNF75D,FAM46A,FICD,CNNM4,TNPO2,CDKN1B,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,TBC1D10B,MYO5B,SEC23A,CDKN2AIP,SLC5A11,TMEM43,CAPN6,TEP1,COX11,SLC11A2,PRKCQ,BCL7B,C15orf39,AKR1E2,SP4,ZNF469,NIN,PRDM11,CMTM7,EPHA10,FYN,JAK1,PPP2R5A,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,ZC3H12B,MLKL,HS3ST3B1,B4GALT3,NR3C2,ATMIN,DENND5B,MRPS9,OTUD5,WASF3,ARHGEF3,ANKRD13D,SLC16A14,JRKL,ATP9A,CCNJL,GPR180,CYB561,APOBEC3H,SEPP1,SPR,PNPLA5,LGALS3BP,SIX4,TMCC3,SNTA1,AKIRIN1,FAM111A,OXCT1,PHF7,PTEN,PRC1,SGK3,ATP8B1,SLC44A2,CNOT6L,MAP3K7,GFI1,SPRY2,OSGIN1,NCOA2,SMC4,PCCB,RASGRF1,ARAP2,SHMT1,CASK,MPP1,DENND1B,TEF,PARP4,FURIN,VAMP3,LRRC1,GPLD1,RGS9,MAMDC4,RCBTB2,PRDX3,SLC25A40,AMMECR1,SERPINB5,CCDC69,CSTF2,PGM2L1,GRIN2D,ETAA1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,USP16,ESYT2,JARID2,EXPH5,LTBP1,NMRK1,TMEM184B,ST13,CPT2,CAMKK1,FLYWCH2,HEBP1,EPHX4,KIF2C,TAF6L,CACNB4,DNER,KREMEN1,DENND2D,TMC1,TSEN34,SH3KBP1,ABCD4,CHPF,ARHGEF10L,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,ANKRD12,POF1B,KIF22,SUN3,RAB20,RP2,NFU1,MYH14,ARNT2,SLC39A10,TECR,PTPRE,RASGRP1,FGFR1OP2,OLFML2A,ATL1,TDP1,SOD1,TRIM8,SYNE3,FOPNL,RNF165,ROR1,MRPS18A,MRPS36,PTGFRN,STK17B,ADRBK2,TCN2,EDNRA,SEC14L2,MDK,CXXC4,LRRC42,NEIL1,ZNF114,ARHGEF19,FASTKD1,DHRS13,UEVLD,IARS2,APBA2,MIIP,PPP2R5D,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,ELOVL7,ASL,ATP6V1E2,SAMD9,PHLPP1,LYSMD4,AIM1L,ZNF432,OTUD1,CA2,LRRN2,EBF4,FNIP1,KNTC1,ACAD8,NCEH1,ALS2CL,HP1BP3,PARD3B,OXR1,HMG20B,FBXO8,RNF113A,AMDHD1,EGFR,MUM1L1,GLCE,GNAS,XKRX,BCAR3,TSC1,ONECUT1,SLC6A6,UTP14C,NFKBIA,CDCA5,ALPK3,PITPNA,KIF12,KLF7,PROM2,GAS2L1,ZSWIM5,FAM92A1,SPC25,IL15,SLC2A8,PSME2,MORC4,GMPR,TDRKH,ZMYND10,MICALL2,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,KHNYN,FRYL,SMO,GOT1,STEAP3,RPN2,F2R,PDIA6,LOXL1,SCYL3,HSPA2,FRS3,MAP3K3,SUSD3,ZNF525,GCA,BAG4,TAF5,SLC39A8,OSTM1,IGSF8,ERBB2IP,SNAPC2,DUSP4,DOCK5,MAP3K6,BFSP1,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,CDS2,SORT1,JKAMP,POC1B,LRP4,ARMC7,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,FAM167A,ZNF212,IRF2BPL,IL17RB,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,TRIM3,BRD7,HSPA13,FAM219A,IQGAP3,SUN2,SYPL1,ADAM17,RAB3B,ASPM,PHLDB3,GCLC,DEPDC4,NR4A1,LRRC66,MBNL3,OGDHL,MPV17L2,SPAG1,MAP1B,KLHL2,HLA-B,C2orf70,PRCP,HNRNPH2,UBE2D2,OTUB2,GEM,ATP6V1C1,SOX8,L1CAM,ZNF596,SNPH |
| 8.491e-15 | -32.40 | kinase binding | molecular function | GO:0019900 | 576 | 156 | 16491 | 2452 |
IBTK,TRIM5,DNAJC3,CCNB1,PJA2,CACNB4,BARD1,PICK1,NCS1,TP73,CDKN2C,CALM2,PCNA,CTNNB1,ELMO2,SHC3,DPYSL2,ZFP36,IL31RA,DLG1,DNM2,PLK1,TNIP1,CASP9,EZR,PRKAR2B,RHEB,PLCG1,CAMK2N2,GPRC5B,MAP3K11,NOD2,PRKCDBP,CAB39,ADIPOR1,HSPB1,PIFO,SCN5A,PPP1R12A,DGKQ,SOX9,PRKAA1,CALM3,RACGAP1,RB1,PFKL,KIF13B,FBXO7,PAK2,MSH2,MAPK7,CCDC88A,SOCS5,KIF20A,MAPKAPK3,CALM1,EPHA1,ILK,CDK5R1,FAS,MAPKAPK2,FNTA,PRKAG2,FAM83D,AURKA,STK39,MAP3K5,PER3,TOB1,RPS6KA3,TMEM173,FBXW5,CCNE2,SPRED1,PAX6,SORBS1,FOXM1,IQGAP1,TP53,PKP2,RASGRP3,MAPK4,BCL2L1,CCNL1,PRKACA,EMP2,ARHGEF16,CCND1,CCNA2,SP100,DACT1,KIF14,PPME1,GYS1,DAB2IP,DLG3,CDKN2D,CHP1,SIRT1,DOCK4,AKT1,PFKFB2,UTRN,CDC25C,IRS2,PTPRJ,ATP1A1,PPP2R5A,CCNB3,STK38,PPP1CB,NRG1,MLKL,SGOL1,ZC3HC1,PRKAR1A,PINK1,TAOK2,TRAF2,ARHGEF7,LRP4,SDC4,PKN1,TRIB2,GSTP1,HDAC9,TOP2A,ADD3,PDCD10,PTEN,CENPJ,PRC1,ACTA2,H2AFY,SPRY2,SYK,MOB4,PIK3R1,RGCC,KIF11,BCAR1,BORA,MAPK8IP1,BCL10,CDK5RAP1,CD8A,BTG1,PRDX3,RAB11FIP2,ACVRL1,E2F1,NR4A3,ARRB1,ITGAV,FZD5,PKIA |
| 8.910e-15 | -32.35 | positive regulation of cellular process | biological process | GO:0048522 | 4598 | 847 | 16441 | 2455 |
ACACB,TRIM24,GRIK2,TRIM5,PNPLA2,DNAJC3,HEXB,RET,XIAP,NRG2,IL18,MORF4L2,SYTL4,SNX9,BARD1,CARD10,LTBP3,PHF1,GRM5,TP73,NPM2,CALM2,DAPK2,PSMD1,TGFBR3,ALDH1A3,DNM2,SEMA3G,PPP1CA,PIK3CD,TIAM1,NEK4,VPS11,SMARCA2,TNIP1,SH3BGRL,DSTN,SPRTN,TFAP2C,PRKAR2B,LOXL2,F12,ICMT,RNF19B,ARF4,LCP1,ABR,PIAS3,PGF,PLCG1,MID1IP1,DNM1L,ANKRD6,LIMK1,MYLK,NOD2,MAP3K11,HDAC1,TMOD2,RNASEL,ITPKA,ARF6,HSPB1,E2F8,GAB1,HOXC13,SCN5A,ITGA6,SOX9,MERTK,LMNA,ELF3,TFAP4,RAC2,WDFY1,MEGF8,FLRT3,NEK2,MAP3K9,SLAIN2,MYDGF,NCAM1,MAPK7,NUP85,PHKG2,MAPKAPK3,SALL4,STAT4,PYM1,SHARPIN,FHL2,MYBL2,CALCRL,PLS1,KIF20B,ELK1,ILK,TP53INP2,PSMA4,RHOB,PLIN5,STK17A,NCOA3,FNTA,ETS2,HTT,SEMA4D,SETD3,OSMR,AURKA,OSCP1,STK39,GDF11,ARPC2,CFAP20,TRPC3,RPS6KA3,TMEM173,RUSC1,XDH,DMPK,GRHL2,NQO1,LFNG,INPP5D,MVB12B,PRKACA,TNFSF9,CCND1,ST5,RNF220,CDH1,SP100,DACT1,RTKN2,ACSL4,RAB27B,RASGEF1A,ETV4,PSRC1,RIPK2,LGALS8,FZD4,PFKFB2,SYNE2,VPS4B,CDCA2,NUSAP1,PXYLP1,GTF2A2,EBF2,NFIX,IRS2,CDK19,WFS1,CORO1C,AXL,WWTR1,RGS14,GEN1,ARNT,MAPK12,CTHRC1,TCAF1,TNRC6C,NKX3-1,TAOK2,CKAP2,TRAF2,BIK,SDC4,FLOT1,PDIA3,PKN1,HDGFRP2,ETS1,GSTP1,TSPAN17,NFAT5,SRPX2,ICAM1,NEO1,CTNNBIP1,CXCL16,ANK1,PDCD10,IRAK1,CTSC,KNDC1,GPC3,MCF2L,FAM20B,CST3,TUBGCP6,BAX,PLEKHF1,IGFBP2,MAPK11,RAG1,ITM2C,S100A6,PLSCR1,FMN1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,UBE2A,ABLIM2,TXK,CNTNAP1,PITX2,BTG1,LDLRAP1,PROM1,ATXN7L3,NR1D2,ACVRL1,SYT7,DBI,NR4A3,ITGAV,HMGA1,CENPE,OSR1,CD81,USF2,SHOX2,FOXA1,ILDR1,AGRN,EPAS1,CNOT8,CUL4B,EPHA4,SUDS3,ARFGEF1,LMCD1,NENF,HDAC6,PDGFB,SDC1,SPTB,FANCI,TFAP2E,PCNA,RPS6KA2,CTNNB1,NPNT,SHC3,P4HB,IL6ST,PSMC2,DDHD2,MITF,ELF5,PASK,TNFRSF18,MYBL1,S100A13,ZNF462,PLK1,THRB,PCGF5,CD55,CITED4,NFE2L1,EZR,KLK6,EAF2,PRKRA,CDK1,VCP,RHEB,OPTN,IRX3,DPYSL3,KDM4D,KLF12,AGPAT2,PRKCDBP,KLF11,PIEZO1,MAFF,RRAGD,PRKAA2,RUNX2,BMF,LGALS3,DNAJB2,RASA2,PSMD7,SORBS3,RACGAP1,NCKAP1,FBLN1,IL18R1,ANO1,CORO1B,BMP2,RB1,TNS3,DAZAP1,VASP,TIMP1,IGF1R,GATA2,PAK2,MDFIC,PIM1,NTN1,WNT3A,PSMA5,RGMB,STRADB,SCRIB,BCL2L13,CDK5R1,MAPKAPK2,PVRL2,CSF1,NLRC5,ATP1B3,SEMA3A,CTBP1,RNF146,RAD21,AVPI1,NF2,UPF3B,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,CCNL1,LPIN3,STIL,EMP2,BCAP31,RAD23A,PDGFA,SRPX,LMO4,PLCG2,BCL6,PLK4,CDH3,ESPN,NOTCH3,TMEM64,LMAN1,EGLN3,DVL2,SULF2,CTH,SIRT1,PPIF,CLCN3,TIMP2,TCEB2,AKT1,S100A4,CDC20,SERTAD3,PTGER4,DAG1,PTGS2,PTPRJ,IDE,RBL1,PSMD3,PTK7,XRCC3,CHMP4B,EFNA5,IRF7,ARHGAP4,CNEP1R1,BIN1,PINK1,MACC1,CD63,ADGRG1,TAB3,DAP,GNAL,SELL,PSMD10,GDF15,HMGN3,JAG2,CRABP2,PARM1,PPP2R3A,NRP2,GBX2,GTF2F2,TFAP2A,TRIM21,BUB1,SYK,CAMK2G,FAM134C,TLE6,DUSP1,P2RX4,NFE2L3,HES1,RHOA,HMGN5,PSMB4,NR3C1,PLAUR,CRIP2,LITAF,PPARA,PRICKLE1,MAML2,TRIM35,CAPNS1,BCAR1,MAPK8IP1,BCL10,CD83,CNOT2,DDAH1,BANK1,TWSG1,SCG2,CDCA7L,NMI,FGF18,E2F1,PPP2R3C,PKD2,ICOSLG,NDFIP1,UBE2C,ARHGEF9,ARHGEF4,LAMP1,TXN,ACVR1,LGR4,ATP8A1,CUL1,GATA3,PSME1,CAMK1D,CCNB1,SEPT4,SLC20A1,PICK1,NCS1,PAK6,HELZ2,CYP1A1,CTGF,STIM1,ZFP36,IL31RA,FOSB,PIK3CA,IRF2,TACSTD2,PACSIN1,TFG,ACVR1C,CASP9,BNIP3L,NBPF3,AURKB,SAV1,LDB2,SLC25A5,POR,RAB2B,AHRR,AREG,PLK2,TBX1,SH2D3C,PPP2R4,NKD1,FAM110C,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,KLF2,CDKN1C,SCOC,DHPS,HLA-E,PRKAA1,SLC25A27,KIF23,SLC1A3,NOTCH2,TNFRSF19,PSIP1,KIAA1161,MECOM,CALR,C9orf69,ITGA3,CYR61,PIK3AP1,DAPK1,SORL1,TNFRSF12A,TSPAN33,GPR161,EEF1D,RIMS2,SOCS5,EPB41L5,KLK5,MMD,MFI2,CALM1,AMER1,ANO6,PIP4K2C,WHSC1,KCTD20,EPHA1,CYFIP2,KDM3A,NFIB,RASA1,STX3,FAS,SERTAD2,PRKAG2,PELI2,ARAP1,FAM83D,PIAS2,NR4A2,EFNA1,MAP3K5,IRF1,EHD1,SPRED1,FOXO6,ARMCX3,DLGAP5,THRA,RPS6KA1,IQGAP1,NDRG1,SUZ12,CD274,EGR3,BCL2L1,AIFM2,FLT3,MNS1,EPM2A,EPS8L2,CD46,NOV,CCNA2,RALB,CDKN1B,DAB2IP,PDE4D,IFIT1,OSBPL7,TSPAN1,FLOT2,MED30,NR2C1,SEMA3B,DOCK4,CDKN2AIP,FOXJ2,DMTN,UTRN,CLSTN1,PRKCQ,SLC11A2,ATP1B1,PYGO1,CBL,ITPR3,FZD7,FYN,PPP2R5A,JAK1,STK26,NGFRAP1,KIAA1804,STAT1,TRIOBP,SLC27A1,KLF5,NRG1,COBL,ATMIN,PRKAR1A,WASF3,ARHGEF3,PCOLCE,EPS8,NES,CBLL1,PBX3,EFNB1,FGF19,TEAD3,ADGRB2,HLA-A,SIX4,WWP2,E2F7,OXCT1,RNF128,PTEN,PRC1,SLC44A2,ERCC2,ERBB3,CITED2,CNOT6L,MAP3K7,GFI1,TRIM62,SPRY2,OSGIN1,MSH6,NCOA2,PDGFC,TGIF1,RASGRF1,CASK,TEF,VAMP3,FURIN,YES1,FOS,GPLD1,CRTC2,FGFR2,PRDX3,TBX18,RYK,GRIN2D,GPER1,LRRK1,FZD5,ARSB,ESPL1,MELK,USP16,RGMA,JARID2,EXPH5,CCNC,CASP3,CAMKK1,ERP29,EPCAM,RAB15,HSF2,GRHL1,CDKL5,SIVA1,TSPAN6,DPYSL2,DLG1,CAPG,AKR1B1,TRPC1,ASH2L,ARNT2,CTTN,SLC39A10,MYRIP,RASGRP1,CYP1B1,SOD1,CXXC5,TRIM8,ASXL1,RNF165,STK17B,EDNRA,SEC14L2,MDK,GPRC5B,HPSE,MADD,CAB39,ADIPOR1,SP6,RAP1GAP,PSMC1,CAPN1,NR2C2,GRN,LASP1,PIFO,PPP1R12A,SERPINE2,BVES,ETV5,CALM3,TEC,ADAMTSL4,DUSP5,SPP1,CA2,FAM20C,KCNN4,PRKCI,SUCO,EBF4,FNIP1,BRAT1,NPTN,C10orf54,ZRANB1,CCDC88A,MDFI,ELK3,HMG20B,PDE5A,EGFR,GNAS,BCAR3,NUDT16,TSC1,ONECUT1,INSR,PLPP3,TMEM30A,CDCA5,NFKBIA,SH3BP4,DCUN1D1,EGFL7,JAK3,TOB1,COL16A1,RARG,KLF7,DRD1,PROM2,SORBS1,PAX6,IL15,PSME2,COL18A1,OSR2,MICALL2,PHLDA1,ARHGEF16,SS18,KIF14,SMO,ZBTB49,TWIST1,DIXDC1,STEAP3,ECE1,EPB41L4B,NFKB2,F2R,HSPA2,UPF3A,FRS3,CHP1,MAP3K3,SOAT1,BAG4,CD40,DOCK5,MAP3K6,ARHGAP35,SOCS3,JADE1,HSF4,BHLHB9,STAT6,SECTM1,OVOL1,CANT1,SPTBN5,AKNA,LIFR,ABCA1,GLIS3,ANXA3,TSPAN15,ARHGEF11,SH3D19,CIT,ARHGEF7,LRP4,TGFBR1,AES,TRIB2,ITGA2B,HDAC9,IRF2BPL,KIF5B,TOP2A,CARD8,ADORA1,ADRBK1,BMP7,TOX2,ZDHHC13,H2AFY,BRD7,IQGAP3,SUN2,DCAF6,ADAM17,RAB3B,WNT10B,ASPM,NR4A1,GCLC,RC3H2,RGCC,RUNX3,MPV17L2,MAP1B,CD8A,CASP7,SWAP70,RAP2C,TADA2B,ARRB1,SOX8,ZMIZ1,AHR,L1CAM,NGEF |
| 9.176e-15 | -32.32 | movement of cell or subcellular component | biological process | GO:0006928 | 1515 | 333 | 16441 | 2455 |
TXN,ACVR1,AK7,RET,KLC2,HEXB,GATA3,NRG2,PSME1,PLXNA1,KIF26A,CALM2,PAK6,PSMD1,TGFBR3,CTGF,ELMO2,DNAH6,PIK3CA,PIK3CD,SEMA3G,TIAM1,KIFC2,UXT,TNS1,KIF13A,LOXL2,ZFAND5,ARF4,LCP1,PLCG1,LIMK1,TBX1,TRAF3IP1,UNC5B,ARF6,HSPB1,F2RL1,SEMA6B,SCN5A,ITGA6,KIF23,APBA1,MERTK,S100A2,RAC2,ITGA3,CYR61,MEGF8,FLRT3,PRKG1,TNFRSF12A,CACNA1D,NCAM1,MYLIP,TTLL1,NUP85,DNAI1,EPB41L5,KIF20A,CALM1,ANO6,KIF20B,EPHA1,NPHP3,ILK,DPYSL4,PSMA4,NFIB,RHOB,RASA1,PTPRF,HTT,SEMA4D,WDR19,MATN2,FAM83D,NR4A2,EFNA1,B4GAT1,NDE1,ARPC2,TRPC3,RPS6KA3,KIF3C,SPRED1,DLGAP5,TUBB4B,CERCAM,INPP5D,RPS6KA1,EGR3,DDR1,APC2,KTN1,NOV,DAB2IP,PDE4D,EPHB4,TSPAN1,DLG3,RASGEF1A,ETV4,SEMA3B,DOCK4,COL6A2,SYNE2,KIF1C,PRKCQ,ATP1B1,ALCAM,EPHA10,IRS2,FYN,JAK1,CORO1C,AXL,STAT1,NRG1,CTHRC1,TAOK2,EPS8,SDC4,PLD2,PKN1,ETS1,IFT27,DNAH3,EFNB1,FGF19,SRPX2,ICAM1,SIX4,SGPL1,RND1,NEO1,CXCL16,ANK1,PDCD10,PTEN,CALD1,FUT8,CD9,KLC3,BAX,ERBB3,PARP9,FARP2,RASGRF1,LCA5,ARHGEF28,B3GNT2,RAPGEF2,PIK3R1,GRIN1,YES1,KIF11,ABLIM2,GPLD1,CNTNAP1,PITX2,BTG1,ACVRL1,FGFR2,RYK,NR4A3,SERPINB5,GRIN2D,SSNA1,CENPE,ITGAV,ARSB,RGMA,MYL9,TNK1,AGRN,EPHA4,F11R,KIF2C,SDC1,DNER,PDGFB,CACNB4,SPTB,SH3KBP1,RPS6KA2,CTNNB1,LRRC6,CDKL5,SHC3,DPYSL2,PSMC2,MITF,DLG1,TRPC1,NTN4,KIF22,CTTN,MYH14,NEB,RASGRP1,CYP1B1,SOD1,MARK1,CELSR2,STRIP2,RNF165,EZR,ARHGDIB,ANLN,CDK1,DPYSL3,MDK,MYL12B,PSMC1,LGALS3,BVES,RASA2,PSMD7,CALM3,RACGAP1,NCKAP1,RAB6A,DUSP5,SSX2IP,CORO1B,SPP1,TNS3,VASP,GATA2,KIF13B,PAK2,COL6A1,PRKCI,BRAT1,ZRANB1,NTN1,WNT3A,PSMA5,CCDC88A,DPYSL5,PODXL2,RGMB,SPA17,SPATA13,STRADB,SCRIB,RANBP9,CDK5R1,EGFR,ITGA7,PLPP3,PITPNA,ATP1B3,PLD1,KIF12,SHROOM2,JAK3,SEMA3A,DRD1,KLF7,DYNLRB1,PSME2,ERBB2,RASGRP3,EMP2,ARHGEF16,PDGFA,TTC21B,ARTN,KIF14,LHX6,SMO,DIXDC1,TWIST1,SCYL3,FRS3,IGSF8,DAG1,MYL12A,ARHGAP35,PTGS2,PTK7,PSMD3,PEX2,EFNA5,SPTBN5,PLXND1,POMGNT2,COPG1,COL9A3,ARHGEF11,CD63,ADGRG1,FRMD6,ARHGEF7,SELL,PSMD10,COL4A5,TGFBR1,ITGA2B,NRP2,SIRPA,GBX2,KIF5B,BMP7,KIAA0319,RPGR,SYK,MYO5A,CAMK2G,GCNT1,HES1,SUN2,ADAM17,RHOA,PSMB4,CFAP46,NR4A1,PLAUR,AMFR,ASPM,AKAP3,BCAR1,MAP1B,ARHGAP24,SCG2,FGF18,SPINT2,PGRMC1,SOX8,L1CAM,NGEF |
| 9.248e-15 | -32.31 | PEREZ_TP53_TARGETS | MSigDB lists | PEREZ_TP53_TARGETS | 1067 | 247 | 17758 | 2588 |
UNKL,GAA,ILDR1,ACVR1,TRIM2,TSC22D3,CACNA2D2,GATA3,FAM102B,NRG2,UBE2Q1,LYNX1,BAIAP3,TP53I11,PLA2G16,KIF26A,FAM46C,LTBP3,CHST2,ZNF275,TFAP2E,TP73,WEE1,SIPA1L2,INPP5E,ELMO2,NPNT,CYP2S1,SLC46A1,FUT1,ARNT2,TINAGL1,MARCH2,ANO4,CPE,IL1RAP,KCNIP3,TRIM8,CXXC5,CELSR2,SPATA18,USP18,HSPA12A,TNFAIP8L1,TNS1,CCNF,TP53I3,ADRBK2,CYP4F3,TYSND1,GINS4,ABR,EDNRA,HS6ST1,GDE1,GNPTAB,ZNF367,TRAF3IP1,MAPK13,UNC5B,TTC39C,GLCCI1,TRAF5,GAB1,LZTS1,HOXC13,GRN,USH1C,CDKN1C,CHCHD7,NUAK1,BVES,ZCCHC24,ADO,ABCG2,HES2,DHRS3,MERTK,PGAP1,KIAA1161,MARCH8,BMP2,AIM1L,IGF1R,FRY,CES2,GATA2,VASN,COL6A1,MDFIC,MOXD1,NTN1,MYLIP,ULBP2,GAD1,ETV7,TSPAN33,TRAK2,KCNJ12,B3GNT7,ADCK3,VWA1,IFIT3,CYFIP2,DPYSL4,GNA11,C3orf58,RHOB,C11orf45,FECH,GNAS,NAAA,INSR,FA2H,SEMA4D,COL13A1,ARAP1,FAM83D,EFNA1,ZBTB34,SHROOM2,IFIH1,APOL2,TMEM173,DOCK9,IRF1,LMO7,FOXO6,GRHL2,GALNT12,INPP5D,CAST,ETNK1,COL18A1,BLCAP,FAM198B,MICALL2,AIFM2,APC2,EXT2,EPS8L2,APOBEC3B,CYP4F11,DACT1,DOK4,LHX6,REEP1,CNNM4,CDKN1B,ESPN,GLB1L2,DAB2IP,IFIT1,ECE1,TMEM64,EPB41L4B,RASGEF1A,MYT1,LOXL1,RNF169,ATG4D,MX1,TMCC2,DOCK4,ENPP4,TAF5,RFK,TMEM144,XRCC6BP1,B3GALNT2,TRIM7,DUOX1,FYN,PTPRJ,CANT1,FAM149A,HS3ST3B1,ANXA9,SLC25A30,LIFR,ISOC1,ABCA1,CBX4,CMTM4,FAM134B,FBLIM1,CTHRC1,COL9A3,TNRC6C,ENO2,SLC16A14,BACE1,BIK,GMCL1,JAG2,KCNC4,RBP7,ARHGEF40,FAM167A,SAC3D1,TMEM63A,IRF2BPL,ANK1,MAGEE1,KNDC1,BMP7,LYPD6,MCF2L,FDXR,CST3,TOX2,TUBGCP6,FAM63A,KLC3,TRIM3,FAM102A,ATP8B1,BRD7,ABCD1,ALDH7A1,FAM134C,CAMK2G,PVRL4,ADAMTS2,LONRF3,PHLDB3,CRIP2,ELOVL3,PLEKHA7,FAM73B,GRTP1,CRISPLD2,USP6,DDAH1,LDLRAP1,SMTNL2,DHRS2,FGF18,ABCB1,ARRB1,FBXO44,CMPK2,HIPK3,LRRC57,CYBRD1,ABCG1,ARHGEF4 |
| 9.297e-15 | -32.31 | biliary_tract | COSMIC cancer mutations | biliary_tract | 16126 | 2444 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,GABARAPL1,SPIN3,CCNB3,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,RAB2B,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,S100A2,TNFRSF19,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,REPS2,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,ZIC5,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.117e-14 | -32.13 | WHITFIELD_CELL_CYCLE_G2 | MSigDB lists | WHITFIELD_CELL_CYCLE_G2 | 168 | 65 | 17758 | 2588 |
CASP3,TUBB4B,NDC80,DHX8,STIL,LTBP3,KCTD9,CDKN2C,CCNA2,CDKL5,RGS3,TNPO2,CDKN1B,KIF22,HSPA2,TUBA4A,PSRC1,ASXL1,CYB5R2,CKAP2L,NUSAP1,CDCA2,AURKB,PIF1,ANLN,CCNF,CDC25C,STK17B,CDK1,TYSND1,STAT1,KPNA2,PPP1R2,HJURP,CKAP2,DCAF7,CDCA8,CDCA3,KIF23,LBR,KIF5B,TOP2A,TIMP1,TFAP2A,SORL1,IQGAP3,HP1BP3,SMC4,NR3C1,BTNL9,C2orf69,KIF20B,KIF11,BORA,G2E3,TRIM69,KBTBD2,NEIL3,FAM83D,UACA,WDR62,UBE2C,CBX5,ESPL1,MELK |
| 1.183e-14 | -32.07 | pancreas-carcinoma | COSMIC cancer mutations | pancreas-carcinoma | 15558 | 2376 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,TGOLN2,FAM46C,SPSB1,SLC35E4,GRM5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,TRIQK,FZD7,POPDC3,ACAD10,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,TTPA,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,EGLN1,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,ZCCHC24,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,RAD23A,CDK14,ABRACL,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,RPL22,AIFM3,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,CAMK2G,IGDCC4,MLEC,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,S100A11,TMEM217,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,ARHGEF3,PCOLCE,SLC16A14,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,FURIN,VAMP3,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CRY2,TMEM37,WBP4,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,NQO1,LFNG,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,SNX10,ETV4,SZRD1,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,PLOD2,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,LBR,AIP,IL22RA1,PARM1,VPS26A,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,PRKAA1,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,REPS2,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,PAPD7,TCFL5,TMEM221,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,MAP1LC3B,ERP29,ECI1,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,STK35,LAMP3,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,FAM81A,QSOX2,TYW3,SPP1,FAM20C,SRP54,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,JAG2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,ZNF75D,CNNM4,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,CHPF,ARHGEF10L,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.206e-14 | -32.05 | intracellular signal transduction | biological process | GO:0035556 | 1835 | 389 | 16441 | 2455 |
RET,KLC2,XIAP,GATA3,CUL1,NRG2,IL18,PSME1,PJA2,CA8,SPSB1,CENPN,CARD10,NCS1,TP73,CALM2,DAPK2,PAK6,RGS12,PSMD1,TGFBR3,CTGF,IL31RA,PIK3CA,PIK3CD,RCAN3,TIAM1,NEK4,CASP9,PRKAR2B,AGO4,AURKB,SAV1,RAB2B,ARF4,ABR,LCP1,SGPP1,CARHSP1,PLCG1,LIMK1,PLK2,SH2D3C,MYLK,MAP3K11,NOD2,MAPK13,EIF4EBP2,ARF6,HSPB1,STARD13,GAB1,FGD1,DDX58,NUAK1,DGKQ,SOX9,PRKAA1,RAB23,MERTK,TNFRSF19,TFAP4,RAC2,RALGPS2,FLRT3,FAM13B,MSH2,DAPK1,MAP3K9,PRKG1,PIKFYVE,MAPK7,NCAM1,MAST4,DGKG,NUP85,RIMS2,SOCS5,PRODH,B9D2,MAPKAPK3,STAT4,CALM1,ERO1A,SHARPIN,DCHS1,CYFIP2,ELK1,ILK,PSMA4,RHOB,RASA1,STK17A,DGKH,PRKAG2,ITPR1,ARAP1,STK39,MAP3K5,NDE1,ARPC2,IFIH1,RPS6KA3,DOCK9,DMPK,ARHGAP11A,SPRED1,TRIP10,RALBP1,INPP5D,RPS6KA1,IQGAP1,NDRG1,MAPK4,NUF2,BCL2L1,PRKACA,KTN1,ZNF385B,EPS8L2,CCNA2,CDH1,SP100,RALB,DOK4,CDKN1B,TAX1BP3,DAB2IP,PDE4D,ARL4D,RAB27B,RASGEF1A,DOCK4,RIPK2,DMTN,PRKCQ,ATP1B1,RAB38,ASB13,ITPR3,IRS2,FYN,JAK1,STK26,AXL,WWTR1,KIAA1804,STAT1,PPP1CB,RAB29,NRG1,RGS14,MAPK12,PRKAR1A,ARHGEF3,TNRC6C,TAOK2,NKX3-1,DEPDC1,CENPI,TRAF2,EPS8,CCM2,ARL4C,FLOT1,PLD2,PKN1,SPDL1,IFT27,FGF19,TEAD3,RND1,CKAP5,DIRAS3,E2F7,PDCD10,IRAK1,PTEN,KNDC1,MCF2L,PRC1,BAX,SGK3,ADAM15,TMBIM6,MAPK11,ERBB3,MAP3K7,NCOA2,MSH6,FARP2,AMOTL2,RASGRF1,ARAP2,ZWINT,ARHGEF28,CTNNAL1,RAPGEF2,PIK3R1,GRIN1,DIAPH2,FOS,SKA1,RGS9,FGFR2,GRIN2D,RABL6,CENPE,ITGAV,LRRK1,NUP37,MELK,MYL9,CASP3,NDC80,ITPR2,KIF2C,PDGFB,SPTB,RAB15,RPS6KA2,CTNNB1,SHC3,ARL1,SIVA1,PSMC2,AKR1B1,DUSP10,RAB20,CTTN,MYH14,RASGRP1,CYP1B1,PLK1,MCTP1,MARK1,CENPA,ITCH,EZR,ARHGDIB,ARFRP1,STK17B,RHEB,PLCH1,CAB39,PIK3C2B,PPP2R5D,MYL12B,PSMC1,PRKAA2,ARAP3,BMF,PPP1R12A,RASA2,ASB9,PDCL,PSMD7,CALM3,RACGAP1,TEC,NCKAP1,RAB6A,PHLPP1,DOCK11,DUSP5,RB1,NOXA1,IGF1R,OCRL,PAK2,PRKCI,FNIP1,MDFIC,SELK,KNTC1,NTN1,PLCB2,PSMA5,CCDC88A,MDFI,CORO2A,STRADB,EGFR,RHPN1,RASGRP2,MAPKAPK2,BCAR3,PHLPP2,NFKBIA,RAB31,RHOBTB2,PLD1,JAK3,DRD1,SPC25,NF2,IL15,FOXM1,PSME2,TP53,DGKA,ERBB2,CCDC68,RHPN2,RASGRP3,MRAS,BCAP31,ARHGEF16,IER3,PDGFA,SS18,KIF14,PLCG2,SMO,BCL6,NFKB2,SCN2A,F2R,DVL2,FRS3,CHP1,MAP3K3,SIRT1,BAG4,AKT1,CDC20,PTGER4,CD40,DUSP4,DOCK5,CDC25C,CASP4,MAP3K6,SOCS3,ARHGAP35,DNAJC10,STK38,PSMD3,RCAN2,SPTBN5,IRF7,ARHGAP4,SGOL1,ZMAT1,PINK1,ARHGEF11,ADGRG1,TAB3,ARHGEF7,CIT,MCTP2,ERCC6L,CDCA8,PSMD10,TGFBR1,SYDE2,SGK1,BUB1,IQGAP3,SYK,CAMK2G,DUSP1,HES1,RAB3B,ADAM17,RHOA,CENPC,PSMB4,DEPDC4,NR4A1,MAPK8IP1,DGKE,PRDX4,ARHGAP24,DDAH1,CASP7,FAT4,RND3,SCG2,NMI,FGF18,RAP2C,E2F1,PKD2,GEM,ARHGEF9,ZBTB33,ARHGEF4,NGEF |
| 1.349e-14 | -31.94 | LINDGREN_BLADDER_CANCER_CLUSTER_3_UP | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_3_UP | 310 | 98 | 17758 | 2588 |
DLGAP5,PTTG1,MORC4,TESK2,ERBB2,RHPN2,KIF2C,BCL2L1,PLA2G16,CCNB1,MNS1,CENPN,UHRF1BP1L,APOBEC3B,CDKN2C,BTG3,PCNA,KIF14,PLK4,RNASEH2A,ACSL4,PXMP4,TFG,CKS2,CPD,PLK1,SOAT1,GCA,LOC81691,ING1,C6orf1,CENPA,FIGNL1,SLC39A8,PANK1,SLC11A2,GLO1,PPP1R14C,H2AFV,CDK1,ARHGEF26,RBL1,KPNA2,RTN3,E2F8,NXT2,DEPDC1,CKAP2,BLVRB,CDCA8,OSGIN2,KIF23,RACGAP1,GMCL1,NUCB2,SAC3D1,SCML1,IL17RB,TOP2A,SNTA1,PIK3AP1,MSH2,NEK2,PRC1,DAPK1,CKS1B,BUB1,NCEH1,C12orf75,EPHX1,PIGC,ADAM17,SHMT1,ZWINT,SPATA13,MYBL2,GGH,KIF11,PRDX4,BCAR3,DDAH1,TWSG1,PRPS2,ITPR1,SLC25A40,DBI,NETO2,E2F1,FAM83D,AURKA,CSTF2,ACADM,CENPE,ATP6V1C1,NCAPG2,UBE2C,CCNB2,MELK |
| 1.412e-14 | -31.89 | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | MSigDB lists | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | 791 | 195 | 17758 | 2588 |
SUN1,SIGIRR,TXN,CAMKK1,FAM129B,GATA3,IL18,F11R,SLC20A1,LTBP3,PLS3,PAK6,WEE1,CPNE2,RGS12,ANKS6,CTGF,ARHGEF37,CASC4,OSBPL3,KLF3,MITF,PSMC2,SERINC2,DUSP10,CLDN4,MTMR11,TINAGL1,WBP4,TRAM1,TIPARP,OLFML2A,ZNF462,KRT80,TRIM8,CD55,CXXC5,SERTAD4,DSTN,NFE2L1,TFAP2C,ARHGDIB,SAV1,MCFD2,ANLN,PTGFRN,RHEB,COL12A1,ABR,SEC14L2,ANKRD10,CDCA4,KCNK1,GDE1,ARRDC1,PIK3C2B,F2RL1,LGALS3,DNAJB2,RASA2,SAMD9,NOTCH2,SLC1A3,DHRS3,S100A2,ANO1,PRRG4,ITGA3,CYR61,TNFRSF12A,NPTN,PIM1,C8orf58,NCEH1,GAD1,MAST4,SNX7,MDFI,CYP26B1,UFD1L,ELK3,PCDH1,MFI2,PRSS23,FHL2,KDM3A,ZDHHC3,EGFR,DHX32,STK17A,BCAR3,PTPRF,PRKAG2,SERTAD2,ETS2,KBTBD2,YOD1,EFNA1,ATP1B3,LTBP2,MAL2,PLD1,NDE1,AKIP1,KLF7,PLEKHG3,SPRED1,SLC25A24,CAST,NDRG1,APOO,IRX4,PKP2,BLCAP,PRSS22,MICALL2,PCBP1,EXT2,C1orf116,IER3,APOBEC3B,ST5,SCNN1A,DACT1,DAB2IP,OSBPL7,FAR1,TMBIM1,SULF2,MYO5B,AGPS,PFKFB2,PTPRU,LGALS8,DRAP1,SAT1,C3orf52,SYNE2,CLSTN1,BCL7B,RAB38,C15orf39,B3GALNT2,CBL,DOCK5,H2AFV,ALCAM,GABARAPL1,ACYP1,CORO1C,WWTR1,OVOL1,TLE1,CHMP4B,PPP2R2D,PRR15,ANXA3,ARHGEF3,MPZL1,TSPAN15,FRMD6,FLOT1,CRABP2,DSE,ETS1,SH2D4A,SGPL1,IRF2BPL,CD109,TMEM87B,GNB5,CALD1,TFAP2A,TAGLN2,CLIP2,SYK,AMOTL2,MOB4,HES1,TGIF1,CTNNAL1,DENND1B,NUB1,PARP4,FURIN,CAPNS1,COL7A1,BTG1,PLOD2,RIN3,SERPINB5,ARFGAP3,ITGAV,PTGES,AHR |
| 1.490e-14 | -31.84 | GNF2_HMMR | MSigDB lists | GNF2_HMMR | 47 | 30 | 17758 | 2588 |
HMMR,PLK1,ZWINT,KIF20A,DLGAP5,FOXM1,ASPM,CDC20,CDCA3,NDC80,CDCA8,NUSAP1,AURKB,KIF11,CDK1,TOP2A,PCNA,CCNA2,PRC1,PLK4,AURKA,BUB1,CENPE,UBE2C,CCNB2,ESPL1,E2F8,MELK,SMC4,CKS2 |
| 1.564e-14 | -31.79 | Golgi apparatus | cellular component | GO:0005794 | 1442 | 315 | 17570 | 2579 |
SLC35D2,HSPG2,IL15RA,ATP8A1,TRAPPC8,TGOLN2,PJA2,SNX9,RIC1,PICK1,CHST2,SLC9A7,NCS1,TP73,AP1M2,MUC4,CTGF,CABP1,STEAP2,KCNS3,FUT1,DNM2,TFG,PACSIN1,CPE,MGAT5,SPEF2,SGCE,SLC35C1,KIF13A,GALNT7,MCFD2,RAB2B,ARF4,DNM1L,AREG,GNPTAB,ATP7B,BMP1,SPRY4,ARF6,F2RL1,RTN3,FGD1,INPPL1,NFKBIE,SCOC,GGA1,HLA-E,NOTCH2,APBA1,PDXDC1,MECOM,CALR,DOPEY2,NECAB3,FBXL14,TPST1,PRKG1,SORL1,PIKFYVE,NCAM1,PPP6R1,TMED2,NAGPA,GCC2,QSOX1,B3GNT7,MMD,KIF20A,ATP8B3,GOLT1A,GLT8D2,AP1AR,HTT,ZDHHC20,ARAP1,FGD6,B4GAT1,ARPC2,PLIN3,TMEM173,RUSC1,PLA2G4A,SLC2A4,GPR107,TRIP10,LFNG,GALNT12,CCDC110,APOO,ATP2C2,RGS20,PRKACA,APC2,CD46,CCNA2,MUC16,CDH1,XYLT2,PDE4D,RAB27B,TMBIM1,SEC23A,COG2,TMEM43,CLSTN1,KIF1C,SLC11A2,PXYLP1,PKMYT1,RAB38,B3GALNT2,GABARAPL1,STX10,STK26,KLF5,RAB29,HS3ST3B1,B4GALT3,IGFBP6,MAN1A2,BACE1,ATP9A,SDC4,CTSZ,PLD2,NUCB2,SLC35G2,HLA-A,NEO1,CAPN2,GOLGA2P5,PDCD10,FUT2,RNF128,CTSC,MGAT1,GPC3,MGAT4A,FAM20B,FUT8,ATP8B1,ITM2C,MSH6,MOB4,PDGFC,B3GNT2,PLSCR1,BCL9,FURIN,C1GALT1C1,DIAPH2,UBAC1,YES1,FAM109A,CPTP,GALNT3,NUCB1,LDLRAP1,FGFR2,SLC35B3,DBI,FAM3C,ARFGAP3,GPER1,FZD5,ARSB,UNC93B1,AGRN,EPHA4,ARFGEF1,NDRG2,MGAT5B,CDIPT,PDGFB,SDC1,TRIM68,CHPF,INPP5E,ENTPD4,GRHL1,CASC4,IMPAD1,LMAN2L,ARL1,PASK,DDHD2,DLG1,DUSP10,RAB20,RP2,CTTN,SCARA3,RASGRP1,ATL1,KCNIP3,LAP3,ACBD3,ARFRP1,PTGFRN,RHEB,OPTN,MAN2A2,HS6ST1,WIPI1,GLA,CHPT1,NRGN,RAP1GAP,PCSK5,PIFO,LMTK3,HLA-F,CNTNAP2,RAB6A,B4GALT4,QSOX2,B4GALNT1,B3GALNT1,FAM20C,OCRL,SLC30A6,PRKCI,MDFIC,HLA-C,WNT3A,MPHOSPH9,CCDC88A,KDELR1,CHSY3,MGAT4B,GYLTL1B,FBXO8,KBTBD8,PRRC1,ZDHHC3,C3orf58,EGFR,NMT2,GLCE,GNAS,H1F0,PLPP3,TMEM30A,RAB31,ZDHHC7,PLD1,IL15,P3H2,XYLT1,FAM198B,EMP2,EXT2,BCAP31,SDF4,PDGFA,WDR44,ZDHHC12,ZDHHC23,SMO,NOTCH3,LMAN1,F2R,SCYL3,CHP1,SULF2,EBAG9,CPD,CLCN3,ACO1,TAPBP,ATP1A1,SECTM1,CANT1,ST3GAL1,NDST3,ABCA1,COPG1,ARFGEF3,FAM134B,GLIS3,GOLIM4,SORT1,TRAPPC10,SH3D19,POMGNT1,DSE,PARM1,XPR1,ZDHHC21,A4GALT,SLC35B4,TFAP2A,ZDHHC13,SLC35A1,RPGR,MYO5A,GCNT1,B3GALT6,SYBU,LITAF,STMN3,MAML2,COL7A1,FNDC3A,HLA-B,SERPINA1,RND3,CSGALNACT1,ARRB1,GLB1,NDFIP1,ABCG1,GOLGB1 |
| 1.761e-14 | -31.67 | LIM_MAMMARY_STEM_CELL_DN | MSigDB lists | LIM_MAMMARY_STEM_CELL_DN | 409 | 119 | 17758 | 2588 |
PLEKHG3,SIGIRR,UNC93B1,SLC35D2,ILDR1,IBTK,NLRX1,ST14,CPT2,HDAC11,PPFIBP2,GATA3,ERBB2,RHPN2,TDRKH,PSME1,SYTL4,DENND2D,TRIM68,ARHGEF16,SLC25A35,KIAA1147,EPCAM,AP1M2,NUP210,CDH1,GRHL1,ZDHHC12,ALDH1A3,CAPG,CLDN4,MYH14,RNASEH2A,DLG3,TRAM1,SULT2B1,SNX10,SCYL3,SULF2,MYO5B,ENPP4,SNX8,GCA,SSH3,CAMSAP3,CLCN3,HTATIP2,ATP1B1,SFXN1,PI4K2B,ALDH5A1,IDE,RBM47,PAFAH1B3,ACAD10,CDK19,STAT6,RAB11FIP1,ARRDC1,MAPK13,RPL22,POMT1,CHPT1,COBL,CMAS,ESRP1,PYROXD2,RASSF7,BIK,PSMD10,ANO9,FBXO6,PKN1,TSPAN17,LGALS3BP,MYO5C,ELF3,DTX3L,ADD3,MLPH,CA2,LYPD3,TMEM62,BDH1,TFAP2A,SORL1,ERBB3,TPCN1,SLC16A5,SLC35A1,NCOA2,TSPAN33,MCCC2,P2RX4,PVRL4,OPLAH,GCC2,SHMT1,SLC37A1,CRB3,CORO2A,SPATA13,C1GALT1C1,RAB3IP,BCL2L13,GRTP1,MFSD7,DHX32,PTPRF,TMEM54,TJP3,FAAH,NAT1,NIPSNAP3A,PPM1H,NUP37,AKIP1,FOXA1,NGEF |
| 1.825e-14 | -31.63 | BLALOCK_ALZHEIMERS_DISEASE_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_UP | 1631 | 346 | 17758 | 2588 |
LAMP1,PNISR,TRIM24,SSH1,PPFIBP2,TAP1,FBXO2,IL18,SPSB1,PHF1,CMTM6,LTBP3,PICK1,DAPK2,CDKN2C,TYMP,TGFBR3,RGS12,STIM1,ZFP36,SNX16,MTMR11,IL10RB,TIPARP,VPS11,TNIP1,CASP9,SLC35C1,SAV1,MYOM1,CYP4F3,ULK2,KDSR,MYLK,PPP2R4,MAP3K11,AGFG2,HDAC1,KLF2,INPPL1,MRC2,CDKN1C,GGA1,HLA-E,ITGA6,SOX9,BMP2K,LMNA,FLII,CD22,RPL39,AIM1,USP1,NCAM1,DLX4,DGKG,EEF1D,RIMS2,TRAK2,REC8,ZNF84,ADCK3,MICB,PTPRH,ELK1,KDM3A,SPTLC2,NFIB,PTPRF,IL1R1,NCOA3,SERTAD2,SLC4A4,MATN2,ARAP1,EFNA1,NDE1,PLIN3,CSRP2,EHD1,DMPK,NQO1,GPR107,S100A11,TRIP10,IQGAP1,CAST,RPS6KA1,ACTR8,THRA,RALBP1,IL13RA1,FTH1,GRK6,DDR1,KTN1,CYP39A1,CYHR1,ST5,ACAP2,FAM46A,SP100,FICD,TAX1BP3,RNASEH2A,PDE4D,PHKA2,NAGA,TMBIM1,SEMA3B,SSH3,COL6A2,COG2,SEPT6,FOXJ2,HTATIP2,C15orf39,H2AFV,ATP10D,IRS2,FYN,PDLIM3,WFS1,WWTR1,TRIOBP,PNPLA6,KLF5,DMWD,MAPK12,TAOK2,FAM189A2,DCAF7,EPS8,OSGIN2,HERC5,PLD2,PKN1,SEPP1,LGALS3BP,ICAM1,PDIA4,WWP2,SGPL1,SNTA1,ADD3,IRAK1,ITGB8,FUT2,MGAT1,CALD1,KCNK5,ATP8B1,TMBIM6,NPTXR,CNPY3,MED22,SMC4,AMOTL2,TGIF1,ARAP2,CASK,TACC1,VAMP3,FBXO9,DIAPH2,LRRC1,YES1,RGS9,LDLRAP1,CTNS,PRDX3,PLOD2,SLC25A40,RIN3,RYK,NR4A3,CCDC69,ERAP1,USF2,EXPH5,CCNI,CASP3,BCAM,AGRN,CPT2,NENF,KIF2C,CDIPT,PDGFB,ECI1,TRIM68,ABCD4,BTG3,METTL7A,TSPAN6,IL6ST,MITF,ABCA2,RP2,TRAM1,MYBL1,HN1L,NFE2L1,ERP44,TCN2,RHEB,EDNRA,SEC14L2,DPYSL3,MAN2A2,NEIL1,KCNMB4,AGPAT2,GPRC5B,PIK3C2B,PPP2R5D,MAFF,RRAGD,PCSK5,USH1C,RUNX2,LRRFIP2,DNAJB2,PDCL,ASB9,ASAH1,FBLN1,C3orf18,MYO5C,TNS3,DAZAP1,IGF1R,KIF13B,PAK2,PIM1,TMEM8A,ETV7,ALDH3A2,CKAP4,SNED1,HMG20B,SCRIB,TCF7,EGFR,GLCE,RASGRP2,SOX13,MAPKAPK2,INSR,FA2H,KBTBD2,ITGA7,CSF1,NFKBIA,RAB31,DONSON,LTBP2,JAK3,APOL2,CTBP1,KLF7,GAS2L1,SORBS1,PAX6,IL15,CTDSPL,TP53,SOD2,GMPR,COL18A1,MRAS,RASGRP3,ARHGEF16,PER2,SRPX,KIF14,PLCG2,BCL6,VAT1,ECE1,F2R,CTDSP2,UPF3A,SEPHS1,MAP3K3,TAF5,MBP,S100A4,SERTAD3,ERBB2IP,SNAPC2,FANCE,DAG1,CASP4,SOCS3,TAPBP,RBL1,STAT6,SECTM1,CANT1,IRF7,LIFR,ABCA1,CTDSP1,BIN1,GOLIM4,PACSIN2,CTSB,LRP4,SELL,HMGN3,COL4A5,DSE,SLC9A2,IL22RA1,NRP2,H1FX,HMGXB4,KIF5B,MDM1,LLGL2,RRBP1,TFAP2A,SGK1,IL17RA,HMGCL,KLF9,CLIP2,RBMS2,NFE2L3,SUN2,HES1,GUSB,GCLC,RC3H2,LITAF,COL7A1,SPAG1,CNOT2,PRCP,FGF18,GEM,ZMIZ1,PLOD3,UBE2C,GOLGB1 |
| 2.083e-14 | -31.50 | GNF2_CCNB2 | MSigDB lists | GNF2_CCNB2 | 56 | 33 | 17758 | 2588 |
DLGAP5,FOXM1,CKAP2,PTTG1,CDCA3,NDC80,CDCA8,RACGAP1,KIF2C,TOP2A,PCNA,CCNA2,PRC1,PLK4,BUB1,SMC4,CKS2,HMMR,ZWINT,KIF20A,ASPM,PBK,CDC20,WHSC1,NUSAP1,KIF11,CDK1,AURKA,CENPE,CCNB2,UBE2C,ESPL1,MELK |
| 2.669e-14 | -31.25 | ONKEN_UVEAL_MELANOMA_UP | MSigDB lists | ONKEN_UVEAL_MELANOMA_UP | 738 | 184 | 17758 | 2588 |
ACACB,PNISR,SLC25A13,ARFGEF1,NENF,NANS,ITPR2,LACTB2,SLC20A1,TYMP,PCNA,RPS6KA2,TM9SF2,SNX16,RGS5,CTTN,TRAM1,S100A13,APOBEC3G,CERS2,CD55,LAP3,KDELR3,GALNT7,LHFPL2,CDK1,ABR,MAN2A2,ANKRD10,TMEM164,MSL1,FASTKD1,WIPI1,GNPTAB,P4HA2,PPP2R4,PRKCDBP,HDAC1,MRPS28,KPNA2,GLA,RAP1GAP,TRAF5,LZTS1,ANXA11,RECQL,CDK17,PARP12,PPP1R12A,LGALS3,CHCHD7,TBC1D1,HLA-E,HLA-F,ITGA6,ASB9,COX6C,PGAP1,GNS,CALR,FRY,COL6A1,OPN3,DAPK1,FXYD5,SORL1,HLA-C,FAR2,MPHOSPH9,ABCC1,SPATA20,ZNF84,OXR1,RHOB,CDK5R1,FRMD4B,SOX13,GNAS,ETS2,RAB31,NR4A2,ARPC2,RAD21,DOCK9,NQO1,DLGAP5,GPR107,S100A11,PSME2,IQGAP1,NDRG1,SOD2,RGS20,COL18A1,KCTD12,EGR3,MGST2,APPBP2,IER3,NOV,CCNA2,CDH1,EFR3A,TACC2,KIF14,REEP1,NOTCH3,EBAG9,CKS2,DOCK4,SOAT1,TIMP2,PSRC1,LGALS8,SYNE2,PTGER4,HTATIP2,SLC11A2,NUSAP1,FZD7,AMZ2,DNAJC10,TAPBP,IDE,C19orf66,CDK19,STAT6,PEX2,WWTR1,STAT1,INPP4B,VSIG10,PDXK,ATMIN,FAM134B,GSDMD,BIN1,TRAPPC10,ATP9A,DAP,CTSB,GTF3A,GDF15,JAG2,INTS8,NTAN1,NUCB2,CAPN2,OXCT1,IRAK1,PPP1R10,CTSC,TMEM62,ALG13,SGK1,WWP1,TAGLN2,SGCB,SLC35A1,RPGR,NCOA2,ATP2B1,S100A6,PHF20L1,ADAM17,IFITM3,GUSB,PAPD7,ZC3H11A,AK4,DIAPH2,EMP3,PRDX4,HLA-B,DGCR2,RIN3,NETO2,ARRB1,PKD2,FHL1,GEM,ATP6V1C1,FZD5,PLOD3 |
| 2.743e-14 | -31.23 | small_cell_carcinoma | COSMIC cancer mutations | small_cell_carcinoma | 10324 | 1675 | 17775 | 2585 |
FAM160B1,IBTK,GRIK2,AK7,SLC25A13,PNPLA2,RET,TRAPPC8,BAIAP3,ISOC2,LACTB2,DPP8,SNX9,SPSB1,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,PHYHIP,MUC4,ATP13A3,DNM2,CRY2,PPP1CA,TMEM37,RNF26,WBP4,TIAM1,CPE,TIPARP,MGAT5,CCDC74A,NEK4,FBXL16,UXT,CDA,TMEM151A,PRKAR2B,RNF19B,ABR,ARF4,LCP1,PIAS3,ENPP1,PLCG1,MPRIP,MID1IP1,ATP7B,CELF5,TRAF3IP1,NOD2,HDAC1,RNASEL,ITPKA,STARD13,HSPB1,NXT2,SCN5A,SEC61G,ITGA6,RAB23,GPSM2,COX6C,FAM21C,TTYH3,ATG4A,TFAP4,SH3D21,RAC2,FRY,RIMS3,MEGF8,FBXO7,RANBP1,FBXL14,MAP3K9,CADPS2,USP1,USP38,ALPK1,CNGA1,MAPK7,ZMYM1,MOXD1,MYLIP,DGKG,KANK3,NUP85,PHKG2,TTLL1,MCCC2,HPS3,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,PCTP,GNA11,PLIN5,MAGED2,IL1R1,CACHD1,SLC4A4,ETS2,DGAT2,CLMN,OSCP1,GDF11,CBX5,ADAMTS16,DMPK,DOCK9,LFNG,CD82,PTTG1,RHBDL3,APOO,C5orf30,GRK6,FAM91A1,REPS1,APPBP2,RBM23,MUC16,ST5,CDH1,XYLT2,RASGEF1A,DLG3,ZNF365,ETV4,MYT1,SNX10,TMCC2,SNX8,COL6A2,ERMP1,RIPK2,APOBEC3D,PFKFB2,PTPN9,SEPT6,SAT1,SYP,DNAJB14,XRCC6BP1,TANC1,SNX12,TRIM7,EBF2,GIGYF1,NFIX,SPIN3,PDLIM3,CCNB3,CDK19,CORO1C,AXL,PNPLA6,MAPK12,CTHRC1,MPZL1,GCAT,TRAF2,BIK,CCM2,OSGIN2,FLOT1,BTN3A1,CTSZ,IFT27,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,SLC25A45,PDCD10,ITGB8,IGSF9,KNDC1,GPC3,TMEM62,CST3,TUBGCP6,BAX,FAM102A,IGFBP2,RAG1,CASD1,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,DUSP23,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,PGBD1,RAB3IP,C4orf27,CNTNAP1,RPL12,PROM1,PLOD2,FAM3C,DBI,PPM1H,FBXO44,ITGAV,CD81,ACOT7,SRSF9,TLL2,TMEM131,TNK1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,DNAJB11,TEX2,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,INPP5E,RPS6KA2,NUP210,CTNNB1,P4HB,NPNT,ARL1,IL6ST,PSMC2,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KRT80,PTPN18,MARK1,CELSR2,CBX6,NFE2L1,CR2,CKAP2L,ARFRP1,SESN1,TRUB1,DZIP1L,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,HOXA9,KLF11,KPNA2,TTC39C,HS6ST3,RRAGD,RMND5A,PARP12,RUNX2,USH1C,HJURP,DNAJB2,FXYD3,RASA2,PSMD7,SORBS3,ADCK5,RAB6A,HES2,NCKAP1,ANO1,MYO5C,TNS3,TIMP1,FRAS1,KIF13B,FCHO1,PIM1,FAR2,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,USP31,MGAT4B,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,CDK5R1,PRX,NMT2,RASGRP2,FOXD2,FA2H,OTUD6B,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,CDAN1,USP43,RAD21,TMX4,TP53,RHPN2,P2RX7,BAHD1,PCBP1,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,TACC2,LMO4,BCL6,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,ATP13A2,PTGS2,IDE,PTPRJ,RBL1,STK38,MMP17,MAOA,XRCC3,IRF7,ARHGAP4,CTDSP1,BIN1,ZMAT1,PINK1,DYRK3,CDH22,CPEB4,TAB3,KLHL13,GNAL,MCTP2,HAL,ERCC6L,GDF15,HMGN3,LBR,IL22RA1,H1FX,NRP2,DNAJB9,FZD6,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,FAM63A,IL17RA,TRIM21,SGK1,CPLX1,ALDH7A1,SYK,ATP2B1,WBP5,DUSP1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,DPP9,MAML2,GGH,COL7A1,TXNDC11,DGKE,BCL10,USP6,DDX23,CNOT2,SCG2,NEIL3,FGF18,E2F1,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,FAM171B,SLC35D2,PNISR,SSH1,HSPG2,VANGL1,TMEM86B,TSC22D3,C1orf198,CUL1,PDGFRL,CAMK1D,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,POLL,KCNS3,PIK3CA,IRF2,SNX16,ARMCX6,METAP2,ACVR1C,CDYL,BNIP3L,LDB2,RAB2B,ANKRD10,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,SEMA6B,RECQL,MRC2,CDKN1C,TBC1D1,TMEM55B,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,TSPAN7,PSIP1,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,AIM1,PPP4R1,MSH2,DAPK1,PRKG1,ADCK2,CACNA1D,KCTD3,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,PIGC,SPATA20,GCC2,PRODH,KCNJ12,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,DCHS1,PYGL,WHSC1,ANTXR1,NFIB,PDE11A,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,PIAS2,FAM83D,MPP2,ARAP1,CABIN1,CDK18,KLK7,HOOK1,IFIH1,SPRED1,KIF3C,TCTN2,DLGAP5,REPS2,CAPN12,GPR107,ST14,CCDC110,NDRG1,RALBP1,CERCAM,FAM78A,BCL2L1,TMEM19,FLT3,DDR1,ZFYVE9,EPM2A,C11orf84,CD46,APOBEC3B,NOV,CCNA2,ACAP2,RALB,EPHB4,RNASEH2A,PDE4D,OSBPL7,TSPAN1,FLOT2,MED30,DOCK4,COG2,FOXJ2,DRAP1,CLSTN1,UTRN,PKMYT1,PYGO1,CBL,ITPR3,ASB13,ALCAM,ATP10D,FZD7,ZMPSTE24,DDOST,ACAD10,NGFRAP1,CCDC149,SLC27A3,COBL,CBX7,MAMDC2,PRKAR1A,IER5L,PLSCR4,DEPDC1,IGFBP6,SLC41A1,CENPI,EPS8,CBLL1,NES,HERC5,PLD2,FBXO6,DNAH3,EFNB1,FGF19,COX7A2,WWP2,CKAP5,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,LONRF3,ZC3H11A,PAPD7,ZKSCAN2,FBXO9,DIAPH2,UBAC1,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,CRTC2,TIMP3,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR62,FZD5,WDR91,ESPL1,CXorf56,DEF6,MELK,UGT8,UBE2Q1,VARS2,PLAC1,TRIM68,ECI1,HTR1D,ADPRHL1,EPCAM,ZFYVE16,RAB15,SIPA1L2,CASC4,CDKL5,METTL7A,ANKFN1,TRPC1,ASH2L,CTTN,MYRIP,BTBD3,IL1RAP,STK35,NLRP4,CXXC5,CENPA,ASXL1,LAP3,ITCH,ACBD3,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SH3GLB2,ZNF165,CAB39,GLA,RBM43,CHPT1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,PPP1R12A,SERPINE2,BVES,PYROXD2,ETV5,ASB9,CALM3,DUSP5,SPP1,PFKL,OCRL,COL6A1,PRKCI,SRP54,LIMCH1,BRAT1,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNED1,SNX7,ELK3,VWA1,KIAA1109,HEATR5A,NUBP1,PDIK1L,STEAP1,RANBP9,INSR,UAP1,TMEM30A,SH3BP4,RAB31,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,RARG,SNX30,DRD1,LMO7,CCNE2,PAX6,SORBS1,HDAC11,PDIA5,MRAS,EXT2,MXD1,CYP4F11,KIF14,FABP6,ZBTB49,EPB41L4B,ECE1,NFKB2,EBAG9,CKS2,SOAT1,PTPRU,MRPS35,GLO1,CD40,TMTC2,CDC25C,FANCE,PDHX,CASP4,SOCS3,ALDH5A1,STAT6,TLE1,MAD2L1BP,ABCA1,KDELC2,ENO2,ARHGEF11,ARHGEF7,SHPRH,SERPINB9,TGFBR1,COL4A5,TRIB2,SBF1,NTAN1,XPR1,HMGXB4,ITGA2B,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,RRBP1,H2AFY,ARVCF,CLIP2,RPGR,RBMS2,B3GALT6,PGM1,DCAF6,WNT10B,SYBU,RC3H2,TTC7A,RUNX3,FAM73B,NDRG3,TCEAL8,LEPR,FOXL1,ARHGAP24,CASP7,SWAP70,RND3,RAP2C,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,NGEF,ACACB,KLK10,TRIM24,ADD1,MRPS15,AASS,TRIM5,DNAJC3,MMADHC,FBXO2,XIAP,SMARCAL1,DHX8,NRG2,MORF4L2,SYTL4,CNTROB,CA8,BARD1,PHF1,EPDR1,DAPK2,TP73,WEE1,PSMD1,RGS12,PQLC2,DNAH6,PPP1R16A,KLF3,ALDH1A3,FUT1,TUBG1,PIK3CD,TINAGL1,ACOX2,ODF2L,APOBEC3G,ERAP2,TUBA4A,NWD1,SMARCA2,TNIP1,SERTAD4,SH3BGRL,RNF11,LOXL2,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,TRIM47,WDR11,ANKRD6,LIMK1,MYLK,MAP3K11,SERPINB6,LSM14B,ARF6,PDPR,GAB1,E2F8,HOXC13,FAM169A,CYP2J2,SOX9,ZNRF3,MERTK,LMNA,RAVER2,ELF3,WDFY1,FAM189A1,CD22,ZIC5,NEK2,STT3B,NCAM1,C9orf72,UFD1L,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,MEST,TP53INP2,RHOB,STK17A,DHX32,PTPRF,NAAA,NCOA3,HTT,TIMM8A,ITPR1,DYSF,AURKA,OSMR,MDH1,FBXO27,NDE1,DRP2,TRPC3,ZNF502,SERPINB1,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,PAPSS2,TMSB15A,GALNT12,WDTC1,RGS20,ETNK1,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,UHRF1BP1L,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,SCN3A,CAMSAP3,LGALS8,FZD4,NRBF2,PLEKHO1,SYNE2,RAB38,IRS2,TTC12,SLC9A6,SIPA1L1,INPP4B,PDXK,RGS14,GEN1,ARNT,GALK1,FARP1,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,GMCL1,ANO9,PKN1,NUCB2,ARHGEF40,ETS1,TSPAN17,SRPX2,PDIA4,NEO1,CAPN2,DTX3L,CXCL16,ANK1,SLC27A6,IRAK1,FAM160A2,ARSG,CTSC,KCNK5,CALD1,MCF2L,ALG13,FDXR,PLEKHF1,ADAM15,NKAPP1,MAPK11,ZNF230,WWP1,AK3,NPTXR,ITM2C,TPCN1,HCN3,LCA5,CTNNAL1,BCL9,RAPGEF2,PLEKHA7,DBR1,SNTB1,CRISPLD2,TXK,PITX2,DCAF10,GALNT3,BTG1,NR1D2,ACVRL1,CCDC6,ZFP30,CENPE,FHL1,HMGA1,NUP37,SHOX2,DCBLD1,FOXA1,SIGIRR,TRIM2,AGRN,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,MCCC1,TP53I11,HDAC6,NUP62CL,PDGFB,PIGL,PCNA,CNTRL,SHC3,MKRN3,ELF5,DDHD2,DUSP10,RGS5,TNFRSF18,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ERP44,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,VCP,PLEKHB1,OPTN,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,CTNND1,PIK3C2B,EPB41L4A,POMT1,GLCCI1,MAFF,PRKAA2,BMF,UBASH3B,HLA-F,RACGAP1,CNTNAP2,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,CORO1B,BMP2,RB1,KIAA0895,VASP,IGF1R,GATA2,SPIN4,TMEM8A,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,WDR72,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,IFIT3,UNC45B,ANKRD29,G2E3,MAPKAPK2,PVRL2,ITGA7,PRPS2,LTBP2,RNF146,NIPA1,NF2,UPF3B,FOXM1,XYLT1,DGKA,CCDC68,ERBB2,RASGRP3,CCNL1,FAM198B,LPIN3,C1orf116,CYP26A1,SDF4,RAD23A,CDK14,SRPX,PLCG2,GYS1,MINPP1,EGLN3,SCN2A,FAR1,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,CDC20,MYL12A,MYPOP,DUOX1,DNAJC10,ATP1A1,PTK7,PSMD3,ADAMTS14,C1orf43,RPL22,LTA4H,NDST3,ZC3HC1,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,MACC1,RUSC2,GNE,BLVRB,PSMD10,NKRF,JAG2,DSE,PPP2R3A,SIRPA,GBX2,CEP97,MAGEE1,ABCD1,BUB1,FAIM,SLC45A3,CAMK2G,FAH,IGDCC4,DLGAP1,HMMR,MLEC,CRB3,NR3C1,AMFR,LITAF,PPARA,TRIM35,AKAP3,FNDC3A,NPDC1,BCAR1,MAPK8IP1,SCRN2,PRDX4,BANK1,FAT4,SERPINA1,ZNF214,ZMYND19,NMI,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,GAA,ACVR1,TMEM41B,KLC2,PPFIBP2,GATA3,PLXNA1,CCNB1,SLC20A1,CHST2,SESN3,CTGF,ZFP36,RGS3,IQCE,PRICKLE3,AOX1,STEAP2,ATRNL1,MTMR11,TFG,SMYD5,LAMP2,ORAI2,TMEM68,KIFC2,PBK,CASP9,HSPA12A,NBPF3,TNS1,AURKB,PIF1,GALNT7,SLC17A5,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ULK2,AHRR,SFXN1,KDSR,FAM177A1,HLF,SLC25A4,RBM47,AREG,PLK2,PTER,GNPTAB,NKD1,TANC2,UNC5B,TRAF5,LZTS1,DLAT,DDX58,MRPL44,CDK17,INPPL1,FRMD4A,DGKQ,SLC25A27,KIF23,C6orf106,NOTCH2,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,PIK3AP1,SNX18,NECAB3,RUNDC3B,CTPS1,SORL1,CD70,TNFRSF12A,PIKFYVE,CTSD,RIMS2,EEF1D,IGSF3,DDB2,QSOX1,B3GNT7,MFI2,KIAA1841,ZNF84,TBC1D8B,MICB,AMER1,PTPRH,ANO6,TMEM133,PIP4K2C,KCTD20,VEZT,KDM3A,FBXO10,RASA1,FAS,DGKH,GABRD,PRKAG2,TMEM54,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PKD1L2,IRF1,ELK4,FRMPD3,PLA2G4A,PLEKHG3,ARMCX3,TRIP10,BROX,SUZ12,IQGAP1,RPS6KA1,IRX4,RNF182,CD274,NUDT12,GNB2,TMPRSS4,APLP2,ZNF75D,DOK4,FICD,TNPO2,CDKN1B,CNNM4,DAB2IP,LGMN,PHKA2,NR2C1,MYO5B,SLC5A11,SEC23A,TMEM43,CAPN6,TEP1,PRKCQ,BCL7B,AKR1E2,SP4,CMTM7,NIN,EPHA10,FYN,ZNF641,JAK1,PPP2R5A,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,MLKL,ZC3H12B,B4GALT3,NR3C2,OTUD5,WASF3,NUDT6,ARHGEF3,PCOLCE,SLC16A14,ATP9A,ARL4C,GPR180,PNPLA5,TMCC3,RND1,SNTA1,PTEN,CENPJ,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,PCCB,RASGRF1,CASK,ARAP2,MPP1,DENND1B,PARP4,FURIN,C1GALT1C1,GPLD1,RGS9,RCBTB2,PRDX3,AMMECR1,CSTF2,SERPINB5,PGM2L1,ETAA1,SLC25A38,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,LTBP1,CASP3,ST13,CPT2,CAMKK1,FLYWCH2,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,ZCCHC12,TSPAN6,CAPG,POF1B,ANKRD12,KIF22,RAB20,RP2,ARNT2,SLC39A10,PTPRE,RASGRP1,OLFML2A,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,TCN2,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,FASTKD1,UEVLD,IARS2,TRIM45,ADIPOR1,APBA2,RAP1GAP,PPP2R5D,MIIP,CPPED1,STARD3NL,LRRFIP2,PEX6,ELOVL7,ATP6V1E2,SAMD9,OTUD1,ZNF432,CA2,LRRN2,EBF4,FNIP1,KNTC1,LRIF1,ALS2CL,PARD3B,OXR1,GYLTL1B,FBXO8,RNF113A,EGFR,MUM1L1,GNAS,BCAR3,XKRX,TSC1,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,PAPD5,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,KIF12,PROM2,FBXW5,KLF7,ZSWIM5,SPC25,ABCG4,MORC4,GMPR,TDRKH,ARHGEF16,LRRC45,SS18,KHNYN,FRYL,SMO,STEAP3,TWIST1,APIP,PDIA6,LOXL1,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,BAG4,KREMEN2,IGSF8,ERBB2IP,DUSP4,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,CANT1,PLXND1,AKNA,SGOL1,PPP2R2D,LIFR,CBX4,ANXA3,CDS2,POC1B,FRMD6,LRP4,AES,NOTUM,TRMT2B,ZNF212,IL17RB,SNX13,MLPH,KIAA0319,BRD7,TRIM3,CKS1B,MXD3,HSPA13,IQGAP3,SUN2,ADAM17,RAB3B,NR4A1,GCLC,PHLDB3,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MAP1B,KLHL2,C2orf70,HNRNPH2,UBE2D2,OTUB2,GLB1,HOXB13,GEM,L1CAM,SNPH,ZNF596 |
| 2.919e-14 | -31.16 | extracellular membrane-bounded organelle | cellular component | GO:0065010 | 2742 | 535 | 17570 | 2579 |
DNAJC3,HEXB,FBXO2,IL18,LYNX1,SNX9,CMTM6,LTBP3,GRM5,EPDR1,CALM2,NAPG,PSMD1,TGFBR3,MUC4,ALDH1A3,DNM2,SEMA3G,PPP1CA,TINAGL1,IL10RB,CPE,MGAT5,TUBA4A,SH3BGRL,DSTN,RNF11,PRKAR2B,F12,ARF4,LCP1,COL12A1,CARHSP1,MYLK,SERPINB6,ARF6,HSPB1,ANXA11,ALDH6A1,CYP2J2,RAB23,TTYH3,GNS,RAC2,SH3D21,CD22,MEGF8,ATP5H,PCYOX1,MYDGF,NCAM1,PLS1,MEST,GNA11,PSMA4,RHOB,CYB5A,PTPRF,NAAA,SCARB2,NCOA3,SLC4A4,APMAP,DYSF,MDH1,B4GAT1,MAL2,ARPC2,CFAP20,SERPINB1,MTM1,NQO1,TUBB4B,CD82,MVB12B,PRKACA,MUC16,SCNN1A,CDH1,TAX1BP3,ACSL4,RAB27B,ENPP4,COL6A2,LGALS8,FZD4,SYNE2,CYS1,VPS4B,SNX12,ALDH3B1,AXL,PDXK,GEN1,ISOC1,GALK1,HSP90B1,MAN1A2,SDC4,FLOT1,PDIA3,CTSZ,NUCB2,GSTP1,ICAM1,CAPN2,PDCD10,FUT2,ITGB8,CTSC,GPC3,MGAT4A,CST3,TUBGCP6,BAX,ADAM15,WWP1,IGFBP2,ITM2C,S100A6,PVRL4,PLSCR1,DUSP23,PLEKHA7,AK4,BLVRA,CRISPLD2,GALNT3,PROM1,RPL12,PLOD2,SYT7,DBI,FAM3C,PLA2G15,ITGAV,CD81,ACOT7,CYBRD1,BCAM,AGRN,GNPDA1,CUL4B,NDRG2,F11R,GALM,SDC1,SLC9A3R2,SUSD2,CPNE2,PCNA,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,SLC44A1,NEB,S100A13,THRB,CD55,CR2,EZR,ERP44,IDH1,CDK1,VCP,RHEB,ARRDC1,CTNND1,MYL12B,PRSS8,LGALS3,FXYD3,PSMD7,ASAH1,RACGAP1,RAB6A,NCKAP1,FBLN1,ANO1,MYO5C,CORO1B,VASP,TIMP1,AHCY,WNT3A,TMEM8A,ALDH3A2,CKAP4,PSMA5,ABCC1,PCBP3,SCRIB,MAPKAPK2,EPN3,PVRL2,CSF1,PRPS2,FAM213A,LTBP2,ATP1B3,UGP2,CTDSPL,PCBP1,C1orf116,SDF4,EFR3A,PLCG2,VAT1,MINPP1,LMAN1,GM2A,CTH,CPD,TIMP2,TCEB2,FIGNL1,S100A4,ACO1,MYL12A,DAG1,RTN4RL1,PTPRJ,ATP1A1,PAFAH1B3,PSMD3,CHMP4B,ANXA9,RPL22,ST3GAL1,LTA4H,CTDSP1,MAN2B2,PACSIN2,ADGRG1,CD63,TAB3,RUSC2,CTSB,BLVRB,GNAL,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,FAM63A,ALDH7A1,ATP2B1,FAH,P2RX4,FBLN5,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,CAPNS1,GGH,FXR2,RNPEP,SCRN2,PRDX4,DDX23,FUCA1,DDAH1,FAT4,SERPINA1,TWSG1,TMC5,PGRMC1,SH3BGRL2,PKD2,ACADM,ICOSLG,TBC1D4,SAT2,LAMP1,GAA,TXN,HSPG2,ATP8A1,FAM129B,PSME1,PLXNA1,NANS,NCS1,AOX1,SERINC2,TACSTD2,MTMR11,TFG,LAMP2,LOC81691,SNTB2,HSPA12A,MGAM,GALNT7,SLC25A5,TP53I3,RAB2B,PTER,PPP2R4,SERPINI1,RTN3,HLA-E,NDUFA4,CALR,DOPEY2,ITGA3,SNX18,VASN,SORL1,CYSRT1,CD70,OSTF1,CTSD,RIMS2,GFPT1,QSOX1,MFI2,PRSS23,ANO6,CALM1,PIP4K2C,PYGL,NPC2,CYFIP2,PKM,JADE2,ANTXR1,STX3,FAS,APPL2,EFNA1,EHD1,SLC2A4,TRIP10,S100A11,ST14,NDRG1,IQGAP1,BROX,KCTD12,FTH1,CD274,DDR1,GNB2,EPS8L2,CD46,APLP2,RALB,DAB2IP,EPHB4,LGMN,TSPAN1,FLOT2,SULT2B1,NAGA,TMBIM1,GPX4,SEMA3B,MYO5B,CLSTN1,UTRN,ATP1B1,AKR1E2,H2AFV,ALCAM,ZMPSTE24,EPHA10,ACYP1,STK26,PPP1CB,RAB29,B4GALT3,WASF3,PLSCR4,PCOLCE,IGFBP6,EPS8,GPR180,SEPP1,SPR,EFNB1,LGALS3BP,HLA-A,COX7A2,WWP2,MGAT1,FUT8,CD9,SLC44A2,TAGLN2,PDGFC,B3GNT2,SHMT1,ALDH2,PARP4,FURIN,C1GALT1C1,UBAC1,YES1,AIF1L,GPLD1,CRTC2,NUCB1,TIMP3,CTNS,ACADSB,PRDX3,ABCB1,ERAP1,SERPINB5,ARSB,RGMA,ST13,CRYM,HEBP1,MPP5,TAF6L,ERP29,ECI1,EPCAM,RAB15,METTL7A,TSPAN6,DPYSL2,DLG1,CAPG,AKR1B1,RP2,CTTN,MYH14,NLRP4,SOD1,ASXL1,LAP3,ITCH,ARHGDIB,TCN2,SEC14L2,ZNF114,GPRC5B,UEVLD,CAB39,GLA,CPPED1,CAPN1,GRN,FAM213B,LASP1,ASL,CALM3,PM20D2,SPP1,CA2,FAM20C,PFKL,OCRL,COL6A1,PRKCI,HLA-C,SLC12A2,SNED1,VWA1,NUBP1,MUM1L1,GNAS,INSR,PLPP3,SH3BP4,CTSA,PITPNA,KIF12,SHROOM2,PROM2,PSME2,HDAC11,SOD2,COL18A1,MRAS,EXT2,SMO,GOT1,ECE1,PDIA6,HSPA2,CHP1,GCA,IGSF8,GLO1,CD40,BHLHB9,SECTM1,CANT1,SPTBN5,LIFR,ANXA3,ENO2,TSPAN15,SERPINB9,ITGA2B,TMEM63A,MLPH,TAF1B,A4GALT,GALNS,H2AFY,ACTA2,HSPA13,MYO5A,SYPL1,PGM1,RAB3B,NDRG3,CTSL,ENDOD1,HLA-B,GAREM2,RND3,PRCP,DHRS2,RAP2C,CTSV,UBE2D2,UACA,GLB1,PLOD3,ATP6V1C1,LRRC57,CD33 |
| 2.919e-14 | -31.16 | extracellular exosome | cellular component | GO:0070062 | 2742 | 535 | 17570 | 2579 |
DNAJC3,HEXB,FBXO2,IL18,LYNX1,SNX9,CMTM6,LTBP3,GRM5,EPDR1,CALM2,NAPG,PSMD1,TGFBR3,MUC4,ALDH1A3,DNM2,SEMA3G,PPP1CA,TINAGL1,IL10RB,CPE,MGAT5,TUBA4A,SH3BGRL,DSTN,RNF11,PRKAR2B,F12,ARF4,LCP1,COL12A1,CARHSP1,MYLK,SERPINB6,ARF6,HSPB1,ANXA11,ALDH6A1,CYP2J2,RAB23,TTYH3,GNS,RAC2,SH3D21,CD22,MEGF8,ATP5H,PCYOX1,MYDGF,NCAM1,PLS1,MEST,GNA11,PSMA4,RHOB,CYB5A,PTPRF,NAAA,SCARB2,NCOA3,SLC4A4,APMAP,DYSF,MDH1,B4GAT1,MAL2,ARPC2,CFAP20,SERPINB1,MTM1,NQO1,TUBB4B,CD82,MVB12B,PRKACA,MUC16,SCNN1A,CDH1,TAX1BP3,ACSL4,RAB27B,ENPP4,COL6A2,LGALS8,FZD4,SYNE2,CYS1,VPS4B,SNX12,ALDH3B1,AXL,PDXK,GEN1,ISOC1,GALK1,HSP90B1,MAN1A2,SDC4,FLOT1,PDIA3,CTSZ,NUCB2,GSTP1,ICAM1,CAPN2,PDCD10,FUT2,ITGB8,CTSC,GPC3,MGAT4A,CST3,TUBGCP6,BAX,ADAM15,WWP1,IGFBP2,ITM2C,S100A6,PVRL4,PLSCR1,DUSP23,PLEKHA7,AK4,BLVRA,CRISPLD2,GALNT3,PROM1,RPL12,PLOD2,SYT7,DBI,FAM3C,PLA2G15,ITGAV,CD81,ACOT7,CYBRD1,BCAM,AGRN,GNPDA1,CUL4B,NDRG2,F11R,GALM,SDC1,SLC9A3R2,SUSD2,CPNE2,PCNA,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,SLC44A1,NEB,S100A13,THRB,CD55,CR2,EZR,ERP44,IDH1,CDK1,VCP,RHEB,ARRDC1,CTNND1,MYL12B,PRSS8,LGALS3,FXYD3,PSMD7,ASAH1,RACGAP1,RAB6A,NCKAP1,FBLN1,ANO1,MYO5C,CORO1B,VASP,TIMP1,AHCY,WNT3A,TMEM8A,ALDH3A2,CKAP4,PSMA5,ABCC1,PCBP3,SCRIB,MAPKAPK2,EPN3,PVRL2,CSF1,PRPS2,FAM213A,LTBP2,ATP1B3,UGP2,CTDSPL,PCBP1,C1orf116,SDF4,EFR3A,PLCG2,VAT1,MINPP1,LMAN1,GM2A,CTH,CPD,TIMP2,TCEB2,FIGNL1,S100A4,ACO1,MYL12A,DAG1,RTN4RL1,PTPRJ,ATP1A1,PAFAH1B3,PSMD3,CHMP4B,ANXA9,RPL22,ST3GAL1,LTA4H,CTDSP1,MAN2B2,PACSIN2,ADGRG1,CD63,TAB3,RUSC2,CTSB,BLVRB,GNAL,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,FAM63A,ALDH7A1,ATP2B1,FAH,P2RX4,FBLN5,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,CAPNS1,GGH,FXR2,RNPEP,SCRN2,PRDX4,DDX23,FUCA1,DDAH1,FAT4,SERPINA1,TWSG1,TMC5,PGRMC1,SH3BGRL2,PKD2,ACADM,ICOSLG,TBC1D4,SAT2,LAMP1,GAA,TXN,HSPG2,ATP8A1,FAM129B,PSME1,PLXNA1,NANS,NCS1,AOX1,SERINC2,TACSTD2,MTMR11,TFG,LAMP2,LOC81691,SNTB2,HSPA12A,MGAM,GALNT7,SLC25A5,TP53I3,RAB2B,PTER,PPP2R4,SERPINI1,RTN3,HLA-E,NDUFA4,CALR,DOPEY2,ITGA3,SNX18,VASN,SORL1,CYSRT1,CD70,OSTF1,CTSD,RIMS2,GFPT1,QSOX1,MFI2,PRSS23,ANO6,CALM1,PIP4K2C,PYGL,NPC2,CYFIP2,PKM,JADE2,ANTXR1,STX3,FAS,APPL2,EFNA1,EHD1,SLC2A4,TRIP10,S100A11,ST14,NDRG1,IQGAP1,BROX,KCTD12,FTH1,CD274,DDR1,GNB2,EPS8L2,CD46,APLP2,RALB,DAB2IP,EPHB4,LGMN,TSPAN1,FLOT2,SULT2B1,NAGA,TMBIM1,GPX4,SEMA3B,MYO5B,CLSTN1,UTRN,ATP1B1,AKR1E2,H2AFV,ALCAM,ZMPSTE24,EPHA10,ACYP1,STK26,PPP1CB,RAB29,B4GALT3,WASF3,PLSCR4,PCOLCE,IGFBP6,EPS8,GPR180,SEPP1,SPR,EFNB1,LGALS3BP,HLA-A,COX7A2,WWP2,MGAT1,FUT8,CD9,SLC44A2,TAGLN2,PDGFC,B3GNT2,SHMT1,ALDH2,PARP4,FURIN,C1GALT1C1,UBAC1,YES1,AIF1L,GPLD1,CRTC2,NUCB1,TIMP3,CTNS,ACADSB,PRDX3,ABCB1,ERAP1,SERPINB5,ARSB,RGMA,ST13,CRYM,HEBP1,MPP5,TAF6L,ERP29,ECI1,EPCAM,RAB15,METTL7A,TSPAN6,DPYSL2,CAPG,DLG1,AKR1B1,RP2,CTTN,MYH14,NLRP4,SOD1,ASXL1,LAP3,ITCH,ARHGDIB,TCN2,SEC14L2,ZNF114,GPRC5B,UEVLD,CAB39,GLA,CPPED1,CAPN1,GRN,FAM213B,LASP1,ASL,CALM3,PM20D2,SPP1,CA2,FAM20C,PFKL,OCRL,COL6A1,PRKCI,HLA-C,SLC12A2,SNED1,VWA1,NUBP1,MUM1L1,GNAS,INSR,PLPP3,SH3BP4,CTSA,PITPNA,KIF12,SHROOM2,PROM2,PSME2,HDAC11,SOD2,COL18A1,MRAS,EXT2,SMO,GOT1,ECE1,PDIA6,HSPA2,CHP1,GCA,IGSF8,GLO1,CD40,BHLHB9,SECTM1,CANT1,SPTBN5,LIFR,ANXA3,ENO2,TSPAN15,SERPINB9,ITGA2B,TMEM63A,MLPH,TAF1B,A4GALT,GALNS,H2AFY,ACTA2,HSPA13,MYO5A,SYPL1,PGM1,RAB3B,NDRG3,CTSL,ENDOD1,HLA-B,GAREM2,RND3,PRCP,DHRS2,RAP2C,CTSV,UBE2D2,UACA,GLB1,PLOD3,ATP6V1C1,LRRC57,CD33 |
| 3.026e-14 | -31.13 | lung-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-small_cell_carcinoma | 10319 | 1674 | 17775 | 2585 |
FAM160B1,IBTK,GRIK2,AK7,SLC25A13,PNPLA2,RET,TRAPPC8,BAIAP3,ISOC2,LACTB2,DPP8,SNX9,SPSB1,CARD10,LTBP3,ZNF275,GRM5,CDKN2C,PHYHIP,MUC4,ATP13A3,DNM2,CRY2,PPP1CA,TMEM37,RNF26,WBP4,TIAM1,CPE,TIPARP,MGAT5,CCDC74A,NEK4,FBXL16,UXT,CDA,TMEM151A,PRKAR2B,RNF19B,ABR,ARF4,LCP1,PIAS3,ENPP1,PLCG1,MPRIP,MID1IP1,ATP7B,CELF5,TRAF3IP1,NOD2,HDAC1,RNASEL,ITPKA,STARD13,HSPB1,NXT2,SCN5A,SEC61G,ITGA6,RAB23,GPSM2,COX6C,FAM21C,TTYH3,ATG4A,TFAP4,SH3D21,RAC2,FRY,RIMS3,MEGF8,FBXO7,RANBP1,FBXL14,MAP3K9,CADPS2,USP1,USP38,ALPK1,CNGA1,MAPK7,ZMYM1,MOXD1,MYLIP,DGKG,KANK3,NUP85,PHKG2,TTLL1,MCCC2,HPS3,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,PCTP,GNA11,PLIN5,MAGED2,IL1R1,CACHD1,SLC4A4,ETS2,DGAT2,CLMN,OSCP1,GDF11,CBX5,ADAMTS16,DMPK,DOCK9,LFNG,CD82,PTTG1,RHBDL3,APOO,C5orf30,GRK6,FAM91A1,REPS1,APPBP2,RBM23,MUC16,ST5,CDH1,XYLT2,RASGEF1A,DLG3,ZNF365,ETV4,MYT1,SNX10,TMCC2,SNX8,COL6A2,ERMP1,RIPK2,APOBEC3D,PFKFB2,PTPN9,SEPT6,SAT1,SYP,DNAJB14,XRCC6BP1,TANC1,SNX12,TRIM7,EBF2,GIGYF1,NFIX,SPIN3,PDLIM3,CCNB3,CDK19,CORO1C,AXL,PNPLA6,MAPK12,CTHRC1,MPZL1,GCAT,TRAF2,BIK,CCM2,OSGIN2,FLOT1,BTN3A1,CTSZ,IFT27,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,SLC25A45,PDCD10,ITGB8,IGSF9,KNDC1,GPC3,TMEM62,CST3,TUBGCP6,BAX,FAM102A,IGFBP2,RAG1,CASD1,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,DUSP23,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,PGBD1,RAB3IP,C4orf27,CNTNAP1,RPL12,PROM1,PLOD2,FAM3C,DBI,PPM1H,FBXO44,ITGAV,CD81,ACOT7,SRSF9,TLL2,TMEM131,TNK1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,DNAJB11,TEX2,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,INPP5E,RPS6KA2,NUP210,CTNNB1,P4HB,NPNT,ARL1,IL6ST,PSMC2,SLC44A1,MITF,TMEM143,ABCA2,NTN4,SCARA3,PLK1,THRB,KRT80,PTPN18,MARK1,CELSR2,CBX6,NFE2L1,CR2,CKAP2L,ARFRP1,SESN1,TRUB1,DZIP1L,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,KCNMB4,HOXA9,KLF11,KPNA2,TTC39C,HS6ST3,RRAGD,RMND5A,PARP12,RUNX2,USH1C,HJURP,DNAJB2,FXYD3,RASA2,PSMD7,SORBS3,ADCK5,RAB6A,HES2,NCKAP1,ANO1,MYO5C,TNS3,TIMP1,FRAS1,KIF13B,FCHO1,PIM1,FAR2,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,USP31,MGAT4B,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,CDK5R1,PRX,NMT2,RASGRP2,FOXD2,FA2H,OTUD6B,NLRC5,ZDHHC7,ZDBF2,PLD1,SEMA3A,CCNB2,CDAN1,USP43,RAD21,TMX4,TP53,RHPN2,P2RX7,BAHD1,PCBP1,EMP2,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,TACC2,LMO4,BCL6,PLK4,CDH3,VAT1,GLB1L2,ESPN,NOTCH3,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,ATP13A2,PTGS2,IDE,PTPRJ,RBL1,STK38,MMP17,MAOA,XRCC3,IRF7,ARHGAP4,CTDSP1,BIN1,ZMAT1,PINK1,DYRK3,CDH22,CPEB4,TAB3,KLHL13,GNAL,MCTP2,HAL,ERCC6L,GDF15,HMGN3,LBR,IL22RA1,H1FX,NRP2,DNAJB9,FZD6,ZDHHC21,CD109,FOXP2,ALPP,CDK16,LYPD6,UBE2J1,FAM63A,IL17RA,TRIM21,SGK1,CPLX1,ALDH7A1,SYK,ATP2B1,WBP5,DUSP1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,DPP9,MAML2,GGH,COL7A1,TXNDC11,DGKE,BCL10,USP6,DDX23,CNOT2,SCG2,NEIL3,FGF18,E2F1,SH3BGRL2,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,FAM171B,SLC35D2,PNISR,SSH1,HSPG2,VANGL1,TMEM86B,TSC22D3,C1orf198,CUL1,PDGFRL,CAMK1D,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,POLL,KCNS3,PIK3CA,IRF2,SNX16,ARMCX6,METAP2,ACVR1C,CDYL,BNIP3L,LDB2,RAB2B,ANKRD10,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,SEMA6B,RECQL,MRC2,CDKN1C,TBC1D1,TMEM55B,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,TSPAN7,PSIP1,DOPEY2,RALGPS2,ZNRF2,BHLHE41,RPL39,AIM1,PPP4R1,MSH2,DAPK1,PRKG1,ADCK2,CACNA1D,KCTD3,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,PIGC,SPATA20,GCC2,PRODH,KCNJ12,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,DCHS1,PYGL,WHSC1,ANTXR1,NFIB,PDE11A,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,PIAS2,FAM83D,MPP2,ARAP1,CABIN1,CDK18,KLK7,HOOK1,IFIH1,SPRED1,KIF3C,TCTN2,DLGAP5,REPS2,CAPN12,GPR107,ST14,CCDC110,NDRG1,RALBP1,CERCAM,FAM78A,BCL2L1,TMEM19,FLT3,DDR1,ZFYVE9,EPM2A,C11orf84,CD46,APOBEC3B,NOV,CCNA2,ACAP2,RALB,EPHB4,RNASEH2A,PDE4D,OSBPL7,TSPAN1,FLOT2,MED30,DOCK4,COG2,FOXJ2,DRAP1,CLSTN1,UTRN,PKMYT1,PYGO1,CBL,ITPR3,ASB13,ALCAM,ATP10D,FZD7,ZMPSTE24,DDOST,ACAD10,NGFRAP1,CCDC149,SLC27A3,COBL,CBX7,MAMDC2,PRKAR1A,IER5L,PLSCR4,DEPDC1,IGFBP6,SLC41A1,CENPI,EPS8,CBLL1,NES,HERC5,PLD2,FBXO6,DNAH3,EFNB1,FGF19,COX7A2,WWP2,CKAP5,SCML1,RASSF8,E2F7,TMEM87B,GNB5,RNF128,DRAM1,CD9,CCDC82,ERBB3,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,LONRF3,ZC3H11A,PAPD7,ZKSCAN2,FBXO9,DIAPH2,UBAC1,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,CRTC2,TIMP3,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR62,FZD5,WDR91,ESPL1,CXorf56,DEF6,MELK,UGT8,UBE2Q1,VARS2,PLAC1,TRIM68,ECI1,HTR1D,ADPRHL1,EPCAM,ZFYVE16,RAB15,SIPA1L2,CASC4,CDKL5,METTL7A,ANKFN1,TRPC1,ASH2L,CTTN,MYRIP,BTBD3,IL1RAP,STK35,NLRP4,CXXC5,CENPA,LAP3,ITCH,ACBD3,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SH3GLB2,ZNF165,CAB39,GLA,RBM43,CHPT1,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,ZNF395,PPP1R12A,SERPINE2,BVES,PYROXD2,ETV5,ASB9,CALM3,DUSP5,SPP1,PFKL,OCRL,COL6A1,PRKCI,SRP54,LIMCH1,BRAT1,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNED1,SNX7,ELK3,VWA1,KIAA1109,HEATR5A,NUBP1,PDIK1L,STEAP1,RANBP9,INSR,UAP1,TMEM30A,SH3BP4,RAB31,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,RARG,SNX30,DRD1,LMO7,CCNE2,PAX6,SORBS1,HDAC11,PDIA5,MRAS,EXT2,MXD1,CYP4F11,KIF14,FABP6,ZBTB49,EPB41L4B,ECE1,NFKB2,EBAG9,CKS2,SOAT1,PTPRU,MRPS35,GLO1,CD40,TMTC2,CDC25C,FANCE,PDHX,CASP4,SOCS3,ALDH5A1,STAT6,TLE1,MAD2L1BP,ABCA1,KDELC2,ENO2,ARHGEF11,ARHGEF7,SHPRH,SERPINB9,TGFBR1,COL4A5,TRIB2,SBF1,NTAN1,XPR1,HMGXB4,ITGA2B,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,LLGL2,MYCL,RRBP1,H2AFY,ARVCF,CLIP2,RPGR,RBMS2,B3GALT6,PGM1,DCAF6,WNT10B,SYBU,RC3H2,TTC7A,RUNX3,FAM73B,NDRG3,TCEAL8,LEPR,FOXL1,ARHGAP24,CASP7,SWAP70,RND3,RAP2C,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,NGEF,ACACB,KLK10,TRIM24,ADD1,MRPS15,AASS,TRIM5,DNAJC3,MMADHC,FBXO2,XIAP,SMARCAL1,DHX8,NRG2,MORF4L2,SYTL4,CNTROB,CA8,BARD1,PHF1,EPDR1,DAPK2,TP73,WEE1,PSMD1,RGS12,PQLC2,DNAH6,PPP1R16A,KLF3,ALDH1A3,FUT1,TUBG1,PIK3CD,TINAGL1,ACOX2,ODF2L,APOBEC3G,ERAP2,TUBA4A,NWD1,SMARCA2,TNIP1,SERTAD4,SH3BGRL,RNF11,LOXL2,ICMT,PPP1R14C,CYP4F3,COL12A1,PGF,TRIM47,WDR11,ANKRD6,LIMK1,MYLK,MAP3K11,SERPINB6,LSM14B,ARF6,PDPR,GAB1,E2F8,HOXC13,FAM169A,CYP2J2,SOX9,ZNRF3,MERTK,LMNA,RAVER2,ELF3,WDFY1,FAM189A1,CD22,ZIC5,NEK2,STT3B,NCAM1,C9orf72,UFD1L,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,MEST,TP53INP2,RHOB,STK17A,DHX32,PTPRF,NAAA,NCOA3,HTT,TIMM8A,ITPR1,DYSF,AURKA,OSMR,MDH1,FBXO27,NDE1,DRP2,TRPC3,ZNF502,SERPINB1,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,PAPSS2,TMSB15A,GALNT12,WDTC1,RGS20,ETNK1,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,UHRF1BP1L,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,RAB27B,CDKN2D,SCN3A,CAMSAP3,LGALS8,FZD4,NRBF2,PLEKHO1,SYNE2,RAB38,IRS2,TTC12,SLC9A6,SIPA1L1,INPP4B,PDXK,RGS14,GEN1,ARNT,GALK1,FARP1,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,GMCL1,ANO9,PKN1,NUCB2,ARHGEF40,ETS1,TSPAN17,SRPX2,PDIA4,NEO1,CAPN2,DTX3L,CXCL16,ANK1,SLC27A6,IRAK1,FAM160A2,ARSG,CTSC,KCNK5,CALD1,ALG13,MCF2L,FDXR,PLEKHF1,ADAM15,NKAPP1,MAPK11,ZNF230,WWP1,AK3,NPTXR,ITM2C,TPCN1,HCN3,LCA5,CTNNAL1,BCL9,RAPGEF2,PLEKHA7,DBR1,SNTB1,CRISPLD2,TXK,PITX2,DCAF10,GALNT3,BTG1,NR1D2,ACVRL1,CCDC6,ZFP30,CENPE,FHL1,HMGA1,NUP37,SHOX2,DCBLD1,FOXA1,SIGIRR,TRIM2,AGRN,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,MCCC1,TP53I11,HDAC6,NUP62CL,PDGFB,PIGL,PCNA,CNTRL,SHC3,MKRN3,ELF5,DDHD2,DUSP10,RGS5,TNFRSF18,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,ERP44,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,RHEB,VCP,PLEKHB1,OPTN,PLCH1,MFAP3L,WIPI1,MAP2,P4HA2,RAB11FIP1,CTNND1,PIK3C2B,EPB41L4A,POMT1,GLCCI1,MAFF,PRKAA2,BMF,UBASH3B,HLA-F,RACGAP1,CNTNAP2,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,CORO1B,BMP2,RB1,KIAA0895,VASP,IGF1R,GATA2,SPIN4,TMEM8A,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,WDR72,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,IFIT3,UNC45B,ANKRD29,G2E3,MAPKAPK2,PVRL2,ITGA7,PRPS2,LTBP2,RNF146,NIPA1,NF2,UPF3B,FOXM1,XYLT1,DGKA,CCDC68,ERBB2,RASGRP3,CCNL1,FAM198B,LPIN3,C1orf116,CYP26A1,SDF4,RAD23A,CDK14,SRPX,PLCG2,GYS1,MINPP1,EGLN3,SCN2A,FAR1,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,FIGNL1,CDC20,MYL12A,MYPOP,DUOX1,DNAJC10,ATP1A1,PTK7,PSMD3,ADAMTS14,C1orf43,RPL22,LTA4H,NDST3,ZC3HC1,CMTM4,MAN2B2,COL9A3,TM2D2,GOLIM4,TRAPPC10,MACC1,RUSC2,GNE,BLVRB,PSMD10,NKRF,JAG2,DSE,PPP2R3A,SIRPA,GBX2,CEP97,MAGEE1,ABCD1,BUB1,FAIM,SLC45A3,CAMK2G,FAH,IGDCC4,DLGAP1,HMMR,MLEC,CRB3,NR3C1,AMFR,LITAF,PPARA,TRIM35,AKAP3,FNDC3A,NPDC1,BCAR1,MAPK8IP1,SCRN2,PRDX4,BANK1,FAT4,SERPINA1,ZNF214,ZMYND19,NMI,NETO2,PGRMC1,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,GAA,ACVR1,TMEM41B,KLC2,PPFIBP2,GATA3,PLXNA1,CCNB1,SLC20A1,CHST2,SESN3,CTGF,ZFP36,RGS3,IQCE,PRICKLE3,AOX1,STEAP2,ATRNL1,MTMR11,TFG,SMYD5,LAMP2,ORAI2,TMEM68,KIFC2,PBK,CASP9,HSPA12A,NBPF3,TNS1,AURKB,PIF1,GALNT7,SLC17A5,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ULK2,AHRR,SFXN1,KDSR,FAM177A1,HLF,SLC25A4,RBM47,AREG,PLK2,PTER,GNPTAB,NKD1,TANC2,UNC5B,TRAF5,LZTS1,DLAT,DDX58,MRPL44,CDK17,INPPL1,FRMD4A,DGKQ,SLC25A27,KIF23,C6orf106,NOTCH2,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,PIK3AP1,SNX18,NECAB3,RUNDC3B,CTPS1,SORL1,CD70,TNFRSF12A,PIKFYVE,CTSD,RIMS2,EEF1D,IGSF3,DDB2,QSOX1,B3GNT7,MFI2,KIAA1841,ZNF84,TBC1D8B,MICB,AMER1,PTPRH,ANO6,TMEM133,PIP4K2C,KCTD20,VEZT,KDM3A,FBXO10,RASA1,FAS,DGKH,GABRD,PRKAG2,TMEM54,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PKD1L2,IRF1,ELK4,FRMPD3,PLA2G4A,PLEKHG3,ARMCX3,TRIP10,BROX,SUZ12,IQGAP1,RPS6KA1,IRX4,RNF182,CD274,NUDT12,GNB2,TMPRSS4,APLP2,ZNF75D,DOK4,FICD,TNPO2,CDKN1B,CNNM4,DAB2IP,LGMN,PHKA2,NR2C1,MYO5B,SLC5A11,SEC23A,TMEM43,CAPN6,TEP1,PRKCQ,BCL7B,AKR1E2,SP4,CMTM7,NIN,EPHA10,FYN,ZNF641,JAK1,PPP2R5A,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,MLKL,ZC3H12B,B4GALT3,NR3C2,OTUD5,WASF3,NUDT6,ARHGEF3,PCOLCE,SLC16A14,ATP9A,ARL4C,GPR180,PNPLA5,TMCC3,RND1,SNTA1,PTEN,CENPJ,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,PCCB,RASGRF1,CASK,ARAP2,MPP1,DENND1B,PARP4,FURIN,C1GALT1C1,GPLD1,RGS9,RCBTB2,PRDX3,AMMECR1,CSTF2,SERPINB5,PGM2L1,ETAA1,SLC25A38,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,LTBP1,CASP3,ST13,CPT2,CAMKK1,FLYWCH2,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,SH3KBP1,CHPF,ABCD4,ARHGEF10L,NKAIN3,C7orf49,ZCCHC12,TSPAN6,CAPG,POF1B,ANKRD12,KIF22,RAB20,RP2,ARNT2,SLC39A10,PTPRE,RASGRP1,OLFML2A,TRIM8,ROR1,PTGFRN,ADRBK2,STK17B,TCN2,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,FASTKD1,UEVLD,IARS2,TRIM45,ADIPOR1,APBA2,RAP1GAP,PPP2R5D,MIIP,CPPED1,STARD3NL,LRRFIP2,PEX6,ELOVL7,ATP6V1E2,SAMD9,OTUD1,ZNF432,CA2,LRRN2,EBF4,FNIP1,KNTC1,LRIF1,ALS2CL,PARD3B,OXR1,GYLTL1B,FBXO8,RNF113A,EGFR,MUM1L1,GNAS,BCAR3,XKRX,TSC1,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,PAPD5,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,KIF12,PROM2,FBXW5,KLF7,ZSWIM5,SPC25,ABCG4,MORC4,GMPR,TDRKH,ARHGEF16,LRRC45,SS18,KHNYN,FRYL,SMO,STEAP3,TWIST1,APIP,PDIA6,LOXL1,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,BAG4,KREMEN2,IGSF8,ERBB2IP,DUSP4,KCTD2,MAP3K6,BFSP1,BHLHB9,PEX2,CANT1,PLXND1,AKNA,SGOL1,PPP2R2D,LIFR,CBX4,ANXA3,CDS2,POC1B,FRMD6,LRP4,AES,NOTUM,TRMT2B,ZNF212,IL17RB,SNX13,MLPH,KIAA0319,BRD7,TRIM3,CKS1B,MXD3,HSPA13,IQGAP3,SUN2,ADAM17,RAB3B,NR4A1,GCLC,PHLDB3,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MAP1B,KLHL2,C2orf70,HNRNPH2,UBE2D2,OTUB2,GLB1,HOXB13,GEM,L1CAM,SNPH,ZNF596 |
| 3.104e-14 | -31.10 | extracellular vesicle | cellular component | GO:1903561 | 2755 | 537 | 17570 | 2579 |
DNAJC3,HEXB,FBXO2,IL18,LYNX1,SNX9,CMTM6,LTBP3,GRM5,EPDR1,CALM2,NAPG,PSMD1,TGFBR3,MUC4,ALDH1A3,DNM2,SEMA3G,PPP1CA,TINAGL1,IL10RB,CPE,MGAT5,TUBA4A,SH3BGRL,DSTN,RNF11,PRKAR2B,F12,ARF4,LCP1,COL12A1,CARHSP1,MYLK,SERPINB6,ARF6,HSPB1,ANXA11,ALDH6A1,CYP2J2,RAB23,TTYH3,GNS,RAC2,SH3D21,CD22,MEGF8,ATP5H,PCYOX1,MYDGF,NCAM1,PLS1,MEST,GNA11,PSMA4,RHOB,CYB5A,PTPRF,NAAA,SCARB2,NCOA3,SLC4A4,APMAP,DYSF,MDH1,B4GAT1,MAL2,ARPC2,CFAP20,SERPINB1,MTM1,NQO1,LFNG,TUBB4B,CD82,MVB12B,PRKACA,MUC16,SCNN1A,CDH1,TAX1BP3,ACSL4,RAB27B,ENPP4,COL6A2,LGALS8,FZD4,SYNE2,CYS1,VPS4B,SNX12,ALDH3B1,AXL,PDXK,GEN1,ISOC1,GALK1,HSP90B1,MAN1A2,SDC4,FLOT1,PDIA3,CTSZ,NUCB2,GSTP1,ICAM1,CAPN2,PDCD10,FUT2,ITGB8,CTSC,GPC3,MGAT4A,CST3,TUBGCP6,BAX,ADAM15,WWP1,IGFBP2,ITM2C,S100A6,PVRL4,PLSCR1,DUSP23,PLEKHA7,AK4,BLVRA,CRISPLD2,GALNT3,PROM1,RPL12,PLOD2,SYT7,DBI,FAM3C,PLA2G15,ITGAV,CD81,ACOT7,CYBRD1,BCAM,AGRN,GNPDA1,CUL4B,NDRG2,F11R,GALM,SDC1,SLC9A3R2,SUSD2,CPNE2,PCNA,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,SLC44A1,NEB,S100A13,THRB,CD55,CR2,EZR,ERP44,IDH1,CDK1,VCP,RHEB,ARRDC1,CTNND1,MYL12B,PRSS8,LGALS3,FXYD3,PSMD7,ASAH1,RACGAP1,RAB6A,NCKAP1,FBLN1,ANO1,MYO5C,CORO1B,VASP,TIMP1,AHCY,WNT3A,TMEM8A,ALDH3A2,CKAP4,PSMA5,ABCC1,PCBP3,SCRIB,MAPKAPK2,EPN3,PVRL2,CSF1,PRPS2,FAM213A,LTBP2,ATP1B3,UGP2,CTDSPL,PCBP1,C1orf116,SDF4,EFR3A,PLCG2,VAT1,MINPP1,LMAN1,GM2A,CTH,CPD,TIMP2,TCEB2,FIGNL1,S100A4,ACO1,MYL12A,DAG1,RTN4RL1,PTPRJ,ATP1A1,PAFAH1B3,PSMD3,CHMP4B,ANXA9,RPL22,ST3GAL1,LTA4H,CTDSP1,MAN2B2,PACSIN2,ADGRG1,CD63,TAB3,RUSC2,CTSB,BLVRB,GNAL,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,FAM63A,ALDH7A1,ATP2B1,FAH,P2RX4,FBLN5,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,CAPNS1,GGH,FXR2,RNPEP,SCRN2,PRDX4,DDX23,FUCA1,DDAH1,FAT4,SERPINA1,TWSG1,TMC5,PGRMC1,SH3BGRL2,PKD2,ACADM,ICOSLG,TBC1D4,SAT2,LAMP1,GAA,TXN,HSPG2,ATP8A1,FAM129B,PSME1,PLXNA1,NANS,NCS1,AOX1,SERINC2,TACSTD2,MTMR11,TFG,LAMP2,LOC81691,SNTB2,HSPA12A,MGAM,GALNT7,SLC25A5,TP53I3,RAB2B,PTER,PPP2R4,SERPINI1,RTN3,HLA-E,NDUFA4,CALR,DOPEY2,ITGA3,SNX18,VASN,SORL1,CYSRT1,CD70,OSTF1,CTSD,RIMS2,GFPT1,QSOX1,MFI2,PRSS23,ANO6,CALM1,PIP4K2C,PYGL,NPC2,CYFIP2,PKM,JADE2,ANTXR1,STX3,FAS,APPL2,EFNA1,EHD1,SLC2A4,TRIP10,S100A11,ST14,NDRG1,IQGAP1,BROX,KCTD12,FTH1,CD274,DDR1,GNB2,EPS8L2,CD46,APLP2,RALB,DAB2IP,EPHB4,LGMN,TSPAN1,FLOT2,SULT2B1,NAGA,TMBIM1,GPX4,SEMA3B,MYO5B,CLSTN1,UTRN,ATP1B1,AKR1E2,H2AFV,ALCAM,ZMPSTE24,EPHA10,ACYP1,STK26,PPP1CB,RAB29,B4GALT3,WASF3,PLSCR4,PCOLCE,IGFBP6,EPS8,GPR180,SEPP1,SPR,EFNB1,LGALS3BP,HLA-A,COX7A2,WWP2,MGAT1,FUT8,CD9,SLC44A2,TAGLN2,PDGFC,B3GNT2,SHMT1,ALDH2,PARP4,FURIN,C1GALT1C1,UBAC1,YES1,AIF1L,GPLD1,CRTC2,NUCB1,TIMP3,CTNS,ACADSB,PRDX3,ABCB1,ERAP1,SERPINB5,ARSB,RGMA,ST13,CRYM,HEBP1,MPP5,TAF6L,ERP29,ECI1,EPCAM,RAB15,METTL7A,TSPAN6,DPYSL2,DLG1,CAPG,AKR1B1,RP2,CTTN,MYH14,NLRP4,SOD1,ASXL1,LAP3,ITCH,ARHGDIB,TCN2,SEC14L2,ZNF114,GPRC5B,UEVLD,CAB39,GLA,CPPED1,CAPN1,GRN,FAM213B,LASP1,SERPINE2,ASL,CALM3,PM20D2,SPP1,CA2,FAM20C,PFKL,OCRL,COL6A1,PRKCI,HLA-C,SLC12A2,SNED1,VWA1,NUBP1,MUM1L1,GNAS,INSR,PLPP3,SH3BP4,CTSA,PITPNA,KIF12,SHROOM2,PROM2,PSME2,HDAC11,SOD2,COL18A1,MRAS,EXT2,SMO,GOT1,ECE1,PDIA6,HSPA2,CHP1,GCA,IGSF8,GLO1,CD40,BHLHB9,SECTM1,CANT1,SPTBN5,LIFR,ANXA3,ENO2,TSPAN15,SERPINB9,ITGA2B,TMEM63A,MLPH,TAF1B,A4GALT,GALNS,H2AFY,ACTA2,HSPA13,MYO5A,SYPL1,PGM1,RAB3B,NDRG3,CTSL,ENDOD1,HLA-B,GAREM2,RND3,PRCP,DHRS2,RAP2C,CTSV,UBE2D2,UACA,GLB1,PLOD3,ATP6V1C1,LRRC57,CD33 |
| 3.104e-14 | -31.10 | extracellular organelle | cellular component | GO:0043230 | 2755 | 537 | 17570 | 2579 |
DNAJC3,HEXB,FBXO2,IL18,LYNX1,SNX9,CMTM6,LTBP3,GRM5,EPDR1,CALM2,NAPG,PSMD1,TGFBR3,MUC4,ALDH1A3,DNM2,SEMA3G,PPP1CA,TINAGL1,IL10RB,CPE,MGAT5,TUBA4A,SH3BGRL,DSTN,RNF11,PRKAR2B,F12,ARF4,LCP1,COL12A1,CARHSP1,MYLK,SERPINB6,ARF6,HSPB1,ANXA11,ALDH6A1,CYP2J2,RAB23,TTYH3,GNS,RAC2,SH3D21,CD22,MEGF8,ATP5H,PCYOX1,MYDGF,NCAM1,PLS1,MEST,GNA11,PSMA4,RHOB,CYB5A,PTPRF,NAAA,SCARB2,NCOA3,SLC4A4,APMAP,DYSF,MDH1,B4GAT1,MAL2,ARPC2,CFAP20,SERPINB1,MTM1,NQO1,LFNG,TUBB4B,CD82,MVB12B,PRKACA,MUC16,SCNN1A,CDH1,TAX1BP3,ACSL4,RAB27B,ENPP4,COL6A2,LGALS8,FZD4,SYNE2,CYS1,VPS4B,SNX12,ALDH3B1,AXL,PDXK,GEN1,ISOC1,GALK1,HSP90B1,MAN1A2,SDC4,FLOT1,PDIA3,CTSZ,NUCB2,GSTP1,ICAM1,CAPN2,PDCD10,FUT2,ITGB8,CTSC,GPC3,MGAT4A,CST3,TUBGCP6,BAX,ADAM15,WWP1,IGFBP2,ITM2C,S100A6,PVRL4,PLSCR1,DUSP23,PLEKHA7,AK4,BLVRA,CRISPLD2,GALNT3,PROM1,RPL12,PLOD2,SYT7,DBI,FAM3C,PLA2G15,ITGAV,CD81,ACOT7,CYBRD1,BCAM,AGRN,GNPDA1,CUL4B,NDRG2,F11R,GALM,SDC1,SLC9A3R2,SUSD2,CPNE2,PCNA,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,SLC44A1,NEB,S100A13,THRB,CD55,CR2,EZR,ERP44,IDH1,CDK1,VCP,RHEB,ARRDC1,CTNND1,MYL12B,PRSS8,LGALS3,FXYD3,PSMD7,ASAH1,RACGAP1,RAB6A,NCKAP1,FBLN1,ANO1,MYO5C,CORO1B,VASP,TIMP1,AHCY,WNT3A,TMEM8A,ALDH3A2,CKAP4,PSMA5,ABCC1,PCBP3,SCRIB,MAPKAPK2,EPN3,PVRL2,CSF1,PRPS2,FAM213A,LTBP2,ATP1B3,UGP2,CTDSPL,PCBP1,C1orf116,SDF4,EFR3A,PLCG2,VAT1,MINPP1,LMAN1,GM2A,CTH,CPD,TIMP2,TCEB2,FIGNL1,S100A4,ACO1,MYL12A,DAG1,RTN4RL1,PTPRJ,ATP1A1,PAFAH1B3,PSMD3,CHMP4B,ANXA9,RPL22,ST3GAL1,LTA4H,CTDSP1,MAN2B2,PACSIN2,ADGRG1,CD63,TAB3,RUSC2,CTSB,BLVRB,GNAL,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,FAM63A,ALDH7A1,ATP2B1,FAH,P2RX4,FBLN5,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,CAPNS1,GGH,FXR2,RNPEP,SCRN2,PRDX4,DDX23,FUCA1,DDAH1,FAT4,SERPINA1,TWSG1,TMC5,PGRMC1,SH3BGRL2,PKD2,ACADM,ICOSLG,TBC1D4,SAT2,LAMP1,GAA,TXN,HSPG2,ATP8A1,FAM129B,PSME1,PLXNA1,NANS,NCS1,AOX1,SERINC2,TACSTD2,MTMR11,TFG,LAMP2,LOC81691,SNTB2,HSPA12A,MGAM,GALNT7,SLC25A5,TP53I3,RAB2B,PTER,PPP2R4,SERPINI1,RTN3,HLA-E,NDUFA4,CALR,DOPEY2,ITGA3,SNX18,VASN,SORL1,CYSRT1,CD70,OSTF1,CTSD,RIMS2,GFPT1,QSOX1,MFI2,PRSS23,ANO6,CALM1,PIP4K2C,PYGL,NPC2,CYFIP2,PKM,JADE2,ANTXR1,STX3,FAS,APPL2,EFNA1,EHD1,SLC2A4,TRIP10,S100A11,ST14,NDRG1,IQGAP1,BROX,KCTD12,FTH1,CD274,DDR1,GNB2,EPS8L2,CD46,APLP2,RALB,DAB2IP,EPHB4,LGMN,TSPAN1,FLOT2,SULT2B1,NAGA,TMBIM1,GPX4,SEMA3B,MYO5B,CLSTN1,UTRN,ATP1B1,AKR1E2,H2AFV,ALCAM,ZMPSTE24,EPHA10,ACYP1,STK26,PPP1CB,RAB29,B4GALT3,WASF3,PLSCR4,PCOLCE,IGFBP6,EPS8,GPR180,SEPP1,SPR,EFNB1,LGALS3BP,HLA-A,COX7A2,WWP2,MGAT1,FUT8,CD9,SLC44A2,TAGLN2,PDGFC,B3GNT2,SHMT1,ALDH2,PARP4,FURIN,C1GALT1C1,UBAC1,YES1,AIF1L,GPLD1,CRTC2,NUCB1,TIMP3,CTNS,ACADSB,PRDX3,ABCB1,ERAP1,SERPINB5,ARSB,RGMA,ST13,CRYM,HEBP1,MPP5,TAF6L,ERP29,ECI1,EPCAM,RAB15,METTL7A,TSPAN6,DPYSL2,CAPG,DLG1,AKR1B1,RP2,CTTN,MYH14,NLRP4,SOD1,ASXL1,LAP3,ITCH,ARHGDIB,TCN2,SEC14L2,ZNF114,GPRC5B,UEVLD,CAB39,GLA,CPPED1,CAPN1,GRN,FAM213B,LASP1,SERPINE2,ASL,CALM3,PM20D2,SPP1,CA2,FAM20C,PFKL,OCRL,COL6A1,PRKCI,HLA-C,SLC12A2,SNED1,VWA1,NUBP1,MUM1L1,GNAS,INSR,PLPP3,SH3BP4,CTSA,PITPNA,KIF12,SHROOM2,PROM2,PSME2,HDAC11,SOD2,COL18A1,MRAS,EXT2,SMO,GOT1,ECE1,PDIA6,HSPA2,CHP1,GCA,IGSF8,GLO1,CD40,BHLHB9,SECTM1,CANT1,SPTBN5,LIFR,ANXA3,ENO2,TSPAN15,SERPINB9,ITGA2B,TMEM63A,MLPH,TAF1B,A4GALT,GALNS,H2AFY,ACTA2,HSPA13,MYO5A,SYPL1,PGM1,RAB3B,NDRG3,CTSL,ENDOD1,HLA-B,GAREM2,RND3,PRCP,DHRS2,RAP2C,CTSV,UBE2D2,UACA,GLB1,PLOD3,ATP6V1C1,LRRC57,CD33 |
| 3.877e-14 | -30.88 | ERB2_UP.V1_UP | MSigDB lists | ERB2_UP.V1_UP | 184 | 68 | 17758 | 2588 |
BCAM,ST13,PAPSS2,HOXB7,EPAS1,GALNT12,NDRG1,CAST,CNOT8,CA8,FAM46C,SLC9A3R2,APOBEC3B,CYP1A1,BCL6,ARNT2,NOTCH3,PDE4D,TSPAN1,EGLN3,LOXL1,PTPRE,ZNF365,HSPA2,CYP1B1,PTPRU,SAT1,PTGER4,BNIP3L,DUSP4,PLEKHB1,SGPP1,WIPI1,SLC9A6,P4HA2,SH3GLB2,MAOA,TTC9,EPB41L4A,RRAGD,CDS2,ENO2,ETV5,SOX9,GDF15,PARM1,CAPN2,VASP,MGAT4A,KCNN4,OPN3,DRAM1,LIMCH1,CADPS2,ULBP2,SLC12A2,S100A6,EPHX1,FADS2,PCDH1,VWA1,NPC2,IL1R1,SLC6A6,SERPINA1,CSGALNACT1,CLMN,ABCG1 |
| 3.938e-14 | -30.87 | PH/PTB_dom | interpro domains | IPR011993 | 379 | 112 | 18293 | 2672 |
PLEKHG3,SPRED1,MTM1,NF2,FAM129B,SPTB,ARHGEF16,EPS8L2,ARHGEF10L,ACAP2,ARHGAP42,RGS12,ELMO2,SHC3,DOK4,OSBPL3,RGS3,PLCG2,DNM2,DAB2IP,RTKN2,EPB41L4B,OSBPL7,TLN2,TIAM1,FRS3,AKT1,PLEKHO1,EZR,TNS1,ANLN,ADRBK2,ARHGEF26,PLEKHB1,ABR,TNS4,IRS2,PLCH1,PLEKHG6,PLCG1,ARHGEF19,MPRIP,TRIOBP,PLEKHG1,SPTBN5,EPB41L4A,APBA2,GAB1,FGD1,ARAP3,ARHGEF3,FARP1,FRMD4A,ARHGEF11,PLEKHJ1,TBC1D1,CIT,FRMD6,ARHGEF7,RASA2,EPS8,CCM2,PLD2,TEC,SBF1,PHLPP1,DOCK11,APBA1,ARHGEF40,TNS3,VASP,ADRBK1,RALGPS2,ANKS1B,MCF2L,RANBP1,MTMR10,EXOC8,PLEKHF1,CADPS2,MYLIP,FARP2,EPB41L5,RASGRF1,ARAP2,ARHGEF28,PLEKHA6,PHLDB3,PLEKHA7,SPATA13,SNTB1,FAM109A,RASA1,MAPK8IP1,FRMD4B,ARHGAP24,DGKH,RGPD5,SWAP70,PLEKHH2,LDLRAP1,ARAP1,APPL2,FGD6,PLD1,TBC1D4,AFAP1,ARHGEF9,DEF6,NGEF,DOCK9,ARHGEF4 |
| 4.067e-14 | -30.83 | system development | biological process | GO:0048731 | 4011 | 749 | 16441 | 2455 |
DOC2A,HECA,ADD1,AK7,RET,MCOLN3,HEXB,NRG2,IL18,KIF26A,GRM5,TP73,CALM2,CDKN2C,WEE1,PSMD1,TGFBR3,ALDH1A3,DNM2,CLDN4,PIK3CD,SEMA3G,PPP1CA,TIPARP,TIAM1,CPE,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,ABR,PGF,PLCG1,ENPP1,LIMK1,ATP7B,TRAF3IP1,MYLK,HDAC1,TMOD2,ITPKA,ARF6,E2F8,GAB1,HOXC13,SCN5A,TMTC3,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,RAC2,FRY,FLRT3,MEGF8,ZIC5,USP1,MYDGF,NCAM1,DGKG,MYLIP,REC8,UFD1L,SALL4,SHARPIN,FHL2,CALCRL,KIF20B,ILK,NPHP3,DPYSL4,PSMA4,GNA11,RHOB,PTPRF,NCOA3,ETS2,TIMM8A,SEMA4D,HTT,DGAT2,CLMN,AURKA,B4GAT1,GDF11,ARPC2,DRP2,NDE1,TRPC3,RPS6KA3,XDH,ADAMTS16,EGLN1,PAPSS2,GRHL2,LFNG,PKP2,PRKACA,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,SNX10,ETV4,MYT1,SSH3,CAMSAP3,COL6A2,LGALS8,FZD4,SAT1,HTATIP2,EBF2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,AXL,CORO1C,WFS1,SIPA1L1,WWTR1,PNPLA6,RGS14,ARNT,MAPK12,CTHRC1,FARP1,TNRC6C,NKX3-1,MAN1A2,SDC4,CCM2,BIK,FLOT1,CTSZ,PKN1,PLPPR4,GSTP1,ETS1,HOXB2,SRPX2,ICAM1,NEO1,SGPL1,CTNNBIP1,ANK1,PDCD10,ITGB8,IGSF9,KNDC1,GPC3,CST3,BAX,ADAM15,TMBIM6,WWP1,RAG1,SGCB,ITM2C,S100A6,POU6F1,ADAMTS2,FMN1,TACC1,BCL9,RAPGEF2,PIK3R1,GRIN1,AK4,ABLIM2,CRISPLD2,TXK,PITX2,CNTNAP1,PROM1,ACVRL1,DBI,NR4A3,ITGAV,FHL1,OSR1,USF2,SHOX2,FOXA1,MYL9,EPAS1,AGRN,CUL4B,EPHA4,SUDS3,ARFGEF1,PHOSPHO1,NDRG2,SDC1,PDGFB,SPTB,SLC9A3R2,PLS3,PCNA,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,MITF,PAPSS1,PSMC2,ELF5,TMEM143,DUSP10,NTN4,NEB,THRB,MARK1,CELSR2,NFE2L1,EZR,CR2,KLK6,PRKRA,ANLN,IDH1,CLCN2,CDK1,RHEB,DPYSL3,IRX3,HS6ST1,MAP2,HOXA9,MYL12B,MAFF,USH1C,RUNX2,LGALS3,RASA2,PSMD7,RACGAP1,CNTNAP2,NCKAP1,DHRS3,IL18R1,PGAP1,BMP2,RB1,TNS3,DAZAP1,VASP,IGF1R,TIMP1,GATA2,FRAS1,KIF13B,PAK2,WNT3A,NTN1,ALDH3A2,PSMA5,CYP26B1,DPYSL5,PCDH1,RGMB,TCF7,SCRIB,EIF2AK1,UNC45B,SMN1,CDK5R1,PRX,MAPKAPK2,MOSPD3,FA2H,COL13A1,ITGA7,CSF1,PHLPP2,PRPS2,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,STIL,SDF4,PER2,TTC21B,PDGFA,TACC2,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,GYS1,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,MBP,TIMP2,AKT1,S100A4,CDC20,PTGER4,MYL12A,DAG1,PTGS2,RTN4RL1,PTPRJ,PAFAH1B3,PTK7,PSMD3,EFNA5,RPL22,LTA4H,POMGNT2,CTDSP1,BIN1,COL9A3,DYRK3,CDH22,ADGRG1,CTSB,PSMD10,JAG2,CRABP2,FZD6,NRP2,PPP2R3A,GBX2,ZDHHC21,CD109,FOXP2,CDK16,TFAP2A,SGK1,HMGCL,SYK,TLE6,CAMK2G,FAM134C,GCNT1,HES1,RHOA,PSMB4,CRIP2,PPARA,PRICKLE1,STMN3,FNDC3A,BBS2,PRDX4,BCL10,FAT4,TWSG1,SCG2,FGF18,E2F1,PGRMC1,PKD2,PPP2R3C,GAA,ACVR1,LGR4,SSH1,HSPG2,TMEM41B,GATA3,CUL1,PSME1,CAMK1D,PLXNA1,VASH1,CCNB1,SEPT4,FAM101B,NCS1,PICK1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,POLL,PIK3CA,TACSTD2,PACSIN1,ZBTB18,SGCE,CASP9,SAV1,CCNF,LDB2,ZFAND5,ULK2,SFXN1,HLF,AREG,PLK2,TBX1,LRIG1,NKD1,BMP1,DHTKD1,SERPINI1,UNC5B,F2RL1,LZTS1,FGD1,KLF2,SEMA6B,INPPL1,CDKN1C,SLC25A27,SLC1A3,NOTCH2,HERC6,APBA1,TNFRSF19,KIAA1161,MECOM,CALR,ITGA3,CYR61,BHLHE41,MSH2,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,RIMS2,TMED2,IGSF3,EPB41L5,MMD,ANO6,DCHS1,AMER1,CALM1,WHSC1,EPHA1,NFIB,STX3,RASA1,FAS,NAB2,MATN2,FAM83D,PCDH19,NR4A2,EFNA1,EHD1,IRF1,FOXO6,SPRED1,TCF25,ST14,RPS6KA1,CAST,IQGAP1,THRA,NDRG1,IRX4,EGR3,BCL2L1,FLT3,DDR1,EPM2A,NOV,APLP2,CCNA2,DOK4,CNNM4,CDKN1B,DAB2IP,PDE4D,EPHB4,SEMA3B,DMTN,UTRN,SLC11A2,PRKCQ,PYGO1,ALCAM,FZD7,CMTM7,EPHA10,FYN,JAK1,STAT1,KLF5,RAB29,NRG1,CBX7,COBL,PRKAR1A,WASF3,JRKL,HAPLN3,CENPI,NES,PBX3,SPR,SEPP1,FGF19,EFNB1,SIX4,TEAD3,ADGRB2,RND1,E2F7,OXCT1,PTEN,FJX1,CD9,ATP8B1,ERCC2,ERBB3,MAP3K7,CITED2,GFI1,TTPA,SPRY2,MSH6,FARP2,RASGRF1,PDGFC,TGIF1,ARHGEF28,B3GNT2,YES1,FOS,GPLD1,CDK5RAP1,RGS9,TIMP3,CTNS,DGCR2,FGFR2,PRDX3,TBX18,RYK,SERPINB5,ERAP1,GRIN2D,GPER1,LRRK1,WDR62,FZD5,ARSB,SLC25A38,MELK,JARID2,RGMA,EXPH5,CASP3,EMX1,UGT8,UBE2Q1,PLAC1,MPP5,DNER,CACNB4,TMC1,EPCAM,LRRC6,CDKL5,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,ASH2L,ARNT2,MYH14,CTTN,BTBD3,RASGRP1,SP5,CYP1B1,ATL1,SOD1,ASXL1,RNF165,EDNRA,MDK,HPSE,GPRC5B,TRIM45,TDRD7,APBA2,NRGN,PSMC1,PPP2R5D,CAPN1,PCSK5,NR2C2,GRN,SERPINE2,BVES,ETV5,CALM3,DUSP5,SPP1,CA2,LRRN2,FAM20C,COL6A1,PRKCI,FNIP1,NPTN,SLC12A2,ETV7,CCDC88A,MDFI,ELK3,HMG20B,RANBP9,C3orf58,EGFR,BCAR3,GNAS,FECH,TSC1,ONECUT1,INSR,TMEM30A,PLPP3,ALPK3,EGFL7,PITPNA,JAK3,SHROOM2,RARG,KLF7,DRD1,PAX6,IL15,PSME2,HDAC11,COL18A1,MRAS,OSR2,MICALL2,PHLDA1,SETDB2,ARTN,KIF14,FRYL,SMO,TWIST1,DIXDC1,ECE1,NFKB2,LOXL1,FRS3,MAP3K3,PTPRU,OSTM1,GLO1,IGSF8,SOCS3,ARHGAP35,HSF4,ALDH5A1,BFSP1,BHLHB9,STAT6,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,PLXND1,LIFR,ANXA3,ARHGEF11,CIT,ARHGEF7,LRP4,AES,COL4A5,TGFBR1,ITGA2B,HDAC9,TOP2A,KIF5B,MDM1,ADORA1,ADRBK1,LLGL2,MYCL,BMP7,TOX2,KIAA0319,TRIM3,ACTA2,RPGR,MYO5A,ADAM17,WNT10B,ASPM,NR4A1,RC3H2,TTC7A,RUNX3,FAM73B,FOXL1,MAP1B,ARHGAP24,LEMD2,CD8A,SWAP70,DHRS2,PRCP,CTSV,SPINT2,CSGALNACT1,ARRB1,HOXB13,PLOD3,ZMIZ1,SOX8,AHR,L1CAM,NGEF |
| 4.393e-14 | -30.76 | HALLMARK_ESTROGEN_RESPONSE_LATE | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_LATE | 201 | 72 | 17758 | 2588 |
KLK10,PAPSS2,ST14,SLC2A8,RET,CACNA2D2,PLAC1,EGR3,PLA2G16,EMP2,STIL,CCND1,BTG3,SCNN1A,RPS6KA2,CDH1,CYP4F11,ZFP36,IL6ST,PLK4,ACOX2,RNASEH2A,SULT2B1,SNX10,TIAM1,CPE,SEMA3B,PPIF,CELSR2,CDC20,TFAP2C,PRKAR2B,MDK,ALDH3B1,JAK1,PDLIM3,AREG,WFS1,XRCC3,MAPK13,ANXA9,GLA,CHPT1,FARP1,BLVRB,COX6C,IL17RB,TOP2A,ADD3,CA2,LLGL2,KCNK5,CD9,OPN3,FAM102A,SGK1,TSPAN13,ALDH3A2,CYP26B1,PRSS23,KIF20A,AMFR,MICB,MEST,FOS,TJP3,SERPINA1,DHRS2,NAB2,RAB31,PTGES,TOB1 |
| 4.573e-14 | -30.72 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | 443 | 125 | 17758 | 2588 |
KIF3C,FAM92A1,IL15,RALBP1,CUL4B,PTTG1,NDC80,RGS20,KCTD12,RNF182,FAM101B,PHLDA1,STIL,SH3KBP1,CHST2,PDGFA,CDKN2C,CPNE2,PSMD1,SRPX,AKR1B1,PIK3CD,LOXL1,SOAT1,PLK1,TIMP2,COL6A2,ASXL1,AGPS,CDC20,CKAP2L,LOXL2,MCFD2,ANLN,ATP10D,FZD7,CMTM7,SOCS3,TRAM2,PTGS2,MPRIP,GPRC5B,POPDC3,CORO1C,AXL,WWTR1,MYLK,PRKCDBP,KDELC2,BIN1,CD99,GLIS3,FBLIM1,RUNX2,MRC2,ARAP3,HJURP,IGFBP6,DEPDC1,SERPINE2,TBC1D1,UBASH3B,ZCCHC24,ETV5,DSE,GSTP1,ARHGEF40,ETS1,S100A2,ADD3,TIMP1,CTSC,FAM20C,CALD1,PPP4R1,COL6A1,TOX2,SLC35B4,FXYD5,SGK1,CCDC82,ACTA2,BUB1,MDFIC,KANK2,PIM1,SGCB,ITM2C,CLIP2,SPRY2,CRTAP,GPR161,CCDC88A,FAM69A,WBP5,SNX7,CYP26B1,PDGFC,ELK3,NR3C1,CTNNAL1,MPP1,EIF5A2,EMP3,PYGL,STRADB,ANTXR1,EGFR,NMT2,MAP1B,FAS,STK17A,FAT4,TWSG1,COL13A1,RAB31,OSMR,LTBP2,FHL1,ITGAV,LRRK1,SHOX2,SERPINB1,SEMA3A,CSRP2 |
| 4.591e-14 | -30.71 | stomach | COSMIC cancer mutations | stomach | 16373 | 2470 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,ZNF618,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,NXPH4,CTSA,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,CAMK2G,IGDCC4,MLEC,NR3C1,AMFR,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,SMYD5,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,KANK3,DGKG,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,GIGYF1,EBF2,GABARAPL1,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,IL22RA1,VPS26A,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,TMEM221,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,LMAN2L,DDHD2,DUSP10,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 5.069e-14 | -30.61 | MEK_UP.V1_UP | MSigDB lists | MEK_UP.V1_UP | 189 | 69 | 17758 | 2588 |
BCAM,ST13,EPAS1,GALNT12,TP53I11,TMPRSS4,CYP1A1,ALDH1A3,CLDN4,EGLN3,LOXL1,PTPRE,CYP1B1,SGCE,TIMP2,PTPRU,PTGER4,ARHGDIB,DUSP4,POR,SGPP1,PTK7,SLC9A6,SH3GLB2,MAOA,TTC9,F2RL1,ENO2,ETV5,GNE,STRN4,ARL4C,EFHD2,GDF15,C11orf95,PARM1,CAPN2,TNS3,VASP,BMP7,KCNN4,MAP3K9,OPN3,SORL1,CADPS2,LIMCH1,ULBP2,SLC12A2,MYO5A,S100A6,GCNT1,EPHX1,FADS2,PCDH1,VWA1,NPC2,EPHA1,SPTLC2,SPAG1,NT5C2,SLC6A6,SLC2A6,CSGALNACT1,CLMN,ARRB1,FHL1,L1CAM,PKIA,ABCG1 |
| 5.634e-14 | -30.51 | pancreas-carcinoid-endocrine_tumour | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour | 7606 | 1280 | 17775 | 2585 |
FAM160B1,IBTK,AK7,SLC25A13,HEXB,RET,CCNO,TRAPPC8,LACTB2,SNX9,SPSB1,LTBP3,CDKN2C,NAPG,PAQR5,DNM2,TIAM1,CPE,MGAT5,NEK4,DSTN,TMEM151A,PRKAR2B,PNKD,ABR,LCP1,ENPP1,C17orf51,ATP7B,CELF5,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,ITPKA,STARD13,HSPB1,ANXA11,ZNF720,MTL5,TTYH3,ATG4A,MARCH8,RAC2,ZCCHC17,FRY,RIMS3,MAP3K9,SLAIN2,CADPS2,ALPK1,CNGA1,MOXD1,DGKG,NUP85,TTLL1,MCCC2,HPS3,PQLC3,FHL2,ELK1,SFXN5,GNA11,PSMA4,CACHD1,FNTA,SLC4A4,S100A5,DGAT2,CLMN,OSCP1,GDF11,TMEM159,CBX5,ADAMTS16,DOCK9,WDR63,PTTG1,RHBDL3,APOO,FAM91A1,MOCS1,KIAA1147,APPBP2,MUC16,ST5,CDH1,SH3BP1,XYLT2,MYT1,SNX10,TMCC2,MX1,SNX8,SEC61B,COL6A2,ERMP1,RIPK2,PFKFB2,AGPS,PTPN9,SEPT6,VPS4B,XRCC6BP1,TANC1,EBF2,GIGYF1,GABARAPL1,PDLIM3,CCNB3,SHROOM3,CDK19,CORO1C,FAM149A,PRIMA1,MAPK12,MZT1,MPZL1,FAM189A2,BACE1,HABP4,CCM2,SDC4,FLOT1,IFT27,SLC25A43,ZFX,PDCD10,ITGB8,KNDC1,TMEM62,TUBGCP6,FAM20B,KLC3,FAM102A,IGFBP2,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,CXorf57,AK4,PGBD1,RAB3IP,C4orf27,PROM1,LDLRAP1,PLOD2,RAB11FIP2,SYT7,FAM3C,PLA2G15,PPM1H,ACOT7,PHC1,TLL2,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,TEX2,F11R,GALM,ITPR2,SPTB,PLS3,CPNE2,INPP5E,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,NPNT,PAPSS1,SLC44A1,TMEM143,NTN4,SMAGP,PLK1,THRB,PTPN18,MARK1,KCNIP3,CELSR2,CR2,EAF2,DZIP1L,TRIM9,TNS4,PLEKHG6,PI4K2B,HS6ST1,TRAM2,KCNMB4,AGPAT2,KLF12,ZNF367,KLF11,KPNA2,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,USH1C,SORBS3,ADCK5,RAB6A,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,FRAS1,ICAM5,FCHO1,SLC30A6,FAR2,WNT3A,NTN1,DPYSL5,PCDH1,PLEKHA6,BTNL9,RGMB,ZSCAN12,BCL2L13,NMT2,C18orf8,KBTBD2,PHLPP2,P4HA3,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,USP43,CTDSPL,TMX4,TP53,RHPN2,P2RX7,BAHD1,STIL,TTC21B,WDR44,TACC2,LMO4,PPME1,CDH3,GLB1L2,ESPN,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,MAOA,XRCC3,CHMP4B,EFNA5,SYT13,FAM134B,BIN1,CMAS,CDH22,CPEB4,CTSB,SCD5,GNAL,MCTP2,HAL,ERI2,ERCC6L,NRP2,SH2D4A,CD109,C16orf74,LYPD6,GTF2F2,IL17RA,TSPAN13,ALDH7A1,HMGCL,FAM134C,ATP2B1,NFE2L3,FBLN5,MOSPD2,CRIP2,DPP9,MAML2,GGH,COL7A1,BBS2,DDX23,CNOT2,DDAH1,FGF18,E2F1,ICOSLG,PTGES,HIPK3,ARHGEF4,GOLGB1,FAM171B,LAMP1,SLC35D2,LGR4,HSPG2,SSH1,VANGL1,C1orf198,CUL1,PDGFRL,NANS,SEPT4,VASH1,PICK1,SLC9A7,ANKS6,ZNF823,STIM1,OSBPL3,PIK3CA,SNX16,SGCE,SPATA18,ACVR1C,CDYL,LDB2,SH2D3C,LRIG1,PRDM5,SERPINI1,F2RL1,CCDC97,FGD1,RECQL,MRC2,TBC1D1,TMEM55B,PRKAA1,APBA1,TNFRSF19,S100A2,PDXDC1,SH3RF2,C9orf69,CALR,DOPEY2,RALGPS2,LYPD3,ZNRF2,MSH2,TMEM51,PRKG1,ADCK2,TPST1,OSTF1,CACNA1D,KCTD3,GPR161,SPATA20,GCC2,PRODH,KCNJ12,KLK5,CEP89,LPGAT1,PYGL,WHSC1,ANTXR1,NFIB,PDE11A,MMP15,NT5C2,AP1AR,SLCO4A1,PLEKHH2,TJP3,PELI2,C1orf21,FAM83D,MPP2,APPL2,AGBL5,SFMBT1,CABIN1,SAMD8,KLK7,ZBTB34,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,THRA,NDRG1,RALBP1,ATP2C2,FAM78A,BCL2L1,TMEM170B,FLT3,CYP39A1,ZFYVE9,EPS8L2,EPM2A,NOV,CCNA2,ACAP2,EPHB4,RNASEH2A,FLOT2,MED30,ATG4D,CLSTN1,UTRN,KIF1C,PYGO1,ATP1B1,CBL,B3GALNT2,ITPR3,ALCAM,ATP10D,DDOST,TSPAN18,ZNF704,COBL,CBX7,MAMDC2,PLSCR4,CENPI,EPS8,CBLL1,HERC5,PBX3,FBXO6,DNAH3,CKAP5,SLC25A36,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,FARP2,TGIF1,PDGFC,ARHGEF28,ZC3H11A,TMEM221,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR91,CXorf56,MELK,DEF6,RGMA,FAF2,UGT8,CRYM,MPP5,MAP1LC3B,ECI1,ADPRHL1,ZFYVE16,SIPA1L2,CASC4,CDKL5,ARHGEF37,SIVA1,ANKFN1,TRPC1,ASH2L,MYRIP,STK35,LAMP3,ASXL1,ACBD3,ITCH,MAN2A2,HPSE,KCNK1,MADD,TDRD7,RBM43,NRGN,CHPT1,CAPN1,NR2C2,PCSK5,LASP1,ZNF395,PPP1R12A,BVES,ETV5,ABCG2,CALM3,FAM81A,ADAMTSL4,QSOX2,TYW3,CES2,FAM20C,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,NPTN,ZRANB1,ETV7,SLC12A2,MDFI,ELK3,PODXL2,PDE5A,KIAA1109,PRRC1,HEATR5A,NUBP1,RANBP9,SOX13,INSR,UAP1,TMEM30A,DCUN1D1,SH3BP4,RAB31,SHROOM2,COL16A1,APOL2,SNX30,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,PDIA5,COL18A1,IL27RA,KCTD9,MXD1,CYP4F11,REEP1,DIXDC1,ZBTB49,EPB41L4B,ECE1,ETHE1,NFKB2,UPF3A,SEPHS1,RFK,PTPRU,GLO1,TMTC2,CDC25C,PDHX,CASP4,ALDH5A1,STAT6,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,KDELC2,GLIS3,GCLM,ARHGEF11,TSPAN15,SH3D19,SERPINB9,TGFBR1,INTS8,TRIB2,RBP7,XPR1,TMEM63A,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,ACTA2,H2AFY,SLC35A1,MYO5A,RBMS2,B3GALT6,PGM1,WNT10B,RC3H2,TTC7A,RUNX3,NDRG3,LEMD2,ENDOD1,SWAP70,CASP7,TRIM69,FIBCD1,SPINT2,CSGALNACT1,ARRB1,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,ACACB,TRIM24,ADD1,IL15RA,AASS,DNAJC3,CACNA2D2,SMARCAL1,DHX8,NRG2,IL18,SYTL4,CA8,KIF26A,BARD1,PHF1,CALM2,DAPK2,TP73,TGFBR3,RGS12,AP1M2,ARHGAP42,KIAA1107,DNAH6,CYP2S1,CABP1,SLC46A1,KLF3,ALDH1A3,RDH14,PIK3CD,ODF2L,ERAP2,TUBA4A,NWD1,TNIP1,SH3BGRL,RNF11,LOXL2,F12,PPP1R14C,MYOM1,CYP4F3,COL12A1,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MRPS28,RELL1,PDPR,GAB1,TMTC3,CYP2J2,SLC36A4,MERTK,LMNA,RAVER2,GNS,WDFY1,FAM189A1,CD22,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,SLC37A1,SALL4,STAT4,MYBL2,CALCRL,SPTLC2,DCP2,DHX32,STK17A,PTPRF,NAAA,SCARB2,MTFMT,SEMA4D,HTT,SETD3,DYSF,AURKA,OSMR,FBXO27,ARPC2,DRP2,NDE1,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,ACTR8,RGS20,WDTC1,PKP2,IL13RA1,ZNF385B,UHRF1BP1L,CDS1,CCND1,RNF220,RTKN2,RAB27B,TMEM9,SCN3A,RNF169,LGALS8,SYNE2,CYS1,NUSAP1,CDCA2,RAB38,IRS2,TTC12,WWTR1,SIPA1L1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,TNRC6C,MAN1A2,PDIA3,GMCL1,ANO9,KCNC4,TSPAN17,PDIA4,NEO1,CAPN2,ANK1,ADD3,SLC27A6,FAM160A2,ARSG,CTSC,ANKS1B,KCNK5,CALD1,ADAM15,MAPK11,WWP1,SGCB,CRTAP,POU6F1,AMOTL2,LCA5,FMN1,FAM160A1,CTNNAL1,RAPGEF2,EIF5A2,GRIN1,DBR1,PLEKHA7,BLVRA,NEURL1B,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,BTG1,CCDC6,ARFGAP3,NUP37,USF2,CYBRD1,DCBLD1,MYL9,AGRN,GNPDA1,FAM199X,PPM1J,EPHA4,MCCC1,NUP62CL,SDC1,PIGL,SHC3,DDHD2,DUSP10,RGS5,TLN2,PXMP4,ANO4,TRAM1,NEB,CCDC38,ZNF462,MCTP1,EZR,ERP44,KLK6,ANLN,IDH1,CLCN2,RHEB,OPTN,MFAP3L,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,PIK3C2B,PIEZO1,EPB41L4A,POMT1,GLCCI1,UBASH3B,RACGAP1,CNTNAP2,DOCK11,IL18R1,PGAP1,RB1,VASP,DAZAP1,KIAA0895,IGF1R,MDFIC,TMEM8A,PLCB2,ALDH3A2,CHSY3,CYP26B1,WDR72,TCF7,UNC45B,ANKRD29,G2E3,PRPS2,LTBP2,ATP1B3,CTBP1,FAM45A,NF2,UGP2,FOXM1,XYLT1,DGKA,ERBB2,CCDC68,CCNL1,PER2,CDK14,RAD23A,SRPX,EFR3A,GYS1,MINPP1,SCN2A,FAR1,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,TCEB2,COQ10B,DUOX1,DNAJC10,RTN4RL1,PTK7,ADAMTS14,ANXA9,NDST3,ZC3HC1,CMTM4,GOLIM4,TRAPPC10,RUSC2,DAP,GABRG2,PSMD10,JAG2,DSE,CRABP2,SIRPA,PPP2R3A,SLC9A2,CEP97,ABCD1,BUB1,FAH,DLGAP1,NR3C1,AMFR,CAPNS1,FXR2,PELI3,FNDC3A,MAPK8IP1,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,CDCA7L,NETO2,PGRMC1,FAM117A,CLIP4,PPP2R3C,PKD2,TBC1D4,NDFIP1,GAA,ACVR1,PPP4R4,TMEM41B,FAM129B,ATP8A1,KLC2,PPFIBP2,GATA3,PLXNA1,PLA2G16,ELMOD2,NCS1,SESN3,ELMO2,ZFP36,IQCE,IL31RA,AOX1,ATRNL1,IQCD,LOC81691,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,GALNT7,SLC17A5,CCNF,SAV1,SLC25A5,ZFAND5,ARHGEF26,SGPP1,AHRR,SFXN1,KDSR,SLC25A4,GNPTAB,TBX1,PTER,NKD1,UNC5B,TANC2,RTN3,DDX58,INPPL1,FRMD4A,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,NOTCH2,SLC1A3,ITGA3,PIK3AP1,NECAB3,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,TMED2,FAM69A,DNAI1,EPB41L5,QSOX1,DDB2,PMPCB,KIAA1841,MFI2,TBC1D8B,PTPRH,PIP4K2C,KCTD20,STX3,RASA1,DGKH,PRKAG2,ISM1,DCK,FGD6,PCDH19,NR4A2,MAP3K5,PKD1L2,FRMPD3,PLA2G4A,CEP70,SUZ12,IQGAP1,RPS6KA1,AIFM2,TMPRSS4,SLC25A35,APLP2,ZNF75D,CNNM4,PHKA2,GPX4,MYO5B,SEC23A,SLC5A11,CAPN6,TMEM43,TEP1,PRKCQ,AKR1E2,H2AFV,SP4,ZNF469,PRDM11,CMTM7,NIN,OSBPL2,ZNF641,FYN,JAK1,PPP2R5A,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,HS3ST3B1,MLKL,NR3C2,DENND5B,MRPS9,WASF3,PCOLCE,ATP9A,CCNJL,GPR180,SPR,SIX4,TMCC3,FAM111A,OXCT1,PTEN,ATP8B1,SLC44A2,NCOA2,PCCB,ARAP2,SHMT1,CASK,ERMAP,MPP1,DENND1B,VAMP3,FURIN,PARP4,LRRC1,RGS9,NUCB1,RCBTB2,PRDX3,SLC25A40,AMMECR1,PGM2L1,GRIN2D,ARSB,OCLN,JARID2,ESYT2,EXPH5,LTBP1,ST13,HEBP1,EPHX4,TAF6L,DNER,CACNB4,TMC1,SH3KBP1,PTCHD4,ABCD4,NKAIN3,ARHGEF10L,LRRC6,IMPAD1,DPYSL2,PHTF1,CAPG,DLG1,AKR1B1,POF1B,SUN3,RAB20,RP2,NFU1,ARNT2,SLC39A10,TECR,PTPRE,RASGRP1,OLFML2A,TDP1,ATL1,TRIM8,FOPNL,RNF165,ROR1,MRPS18A,PTGFRN,ADRBK2,TCN2,EDNRA,CXXC4,ARHGEF19,FASTKD1,DHRS13,IARS2,TRIM45,CCDC74B,ADIPOR1,APBA2,PSMC1,PPP2R5D,CPPED1,LRRFIP2,ELOVL7,SAMD9,PHLPP1,AIM1L,EBF4,FNIP1,FXYD5,KNTC1,LRIF1,ALS2CL,FBXO8,AMDHD1,EGFR,MUM1L1,GNAS,XKRX,FECH,BCAR3,TSC1,SLC6A6,UTP14C,PITPNA,KLF7,ZSWIM5,FAM92A1,SPC25,SLC2A8,GMPR,ZMYND10,PATL2,MICALL2,LRRC45,SLC25A48,SS18,ZDHHC12,FRYL,RPN2,F2R,LOXL1,BAG4,KREMEN2,SLC39A8,DOCK5,BFSP1,OVOL1,VSIG10,PLXND1,AKNA,LIFR,ANXA3,POC1B,FRMD6,ARMC7,LRP4,TRMT2B,ZNF212,IL17RB,SNX13,ADORA1,GALNS,KIAA0319,BRD7,TRIM3,IQGAP3,SYPL1,ADAM17,RAB3B,ASPM,DEPDC4,PHLDB3,NR4A1,MBNL3,LRRC66,OGDHL,MAP1B,KLHL2,PRCP,UBE2D2,HOXB13,LRRC57 |
| 5.867e-14 | -30.47 | WHITFIELD_CELL_CYCLE_G2_M | MSigDB lists | WHITFIELD_CELL_CYCLE_G2_M | 202 | 72 | 17758 | 2588 |
DLGAP5,FOXM1,TUBB4B,VANGL1,NUF2,KIF2C,CNTROB,GRK6,ASPHD2,PAK6,SS18,CCNA2,KIF14,GOT1,PIK3CD,RASGEF1A,CDKN2D,CKS2,SEPHS1,PLK1,CENPA,ASXL1,PBK,PTPN9,CDC20,TNFAIP8L1,NUSAP1,ARHGDIB,DUSP4,ANLN,KCTD2,FYN,CTNND1,MAPK13,ZC3HC1,MZT1,DEPDC1,CKAP2,CIT,CDCA3,TXNDC9,LBR,LMNA,CKAP5,KIF5B,BMP2,ZFX,PPP1R10,NEK2,CKS1B,SLC44A2,BUB1,HSPA13,KLF9,ZMYM1,CCDC88A,HP1BP3,HMMR,TGIF1,HMG20B,KIF20B,G2E3,FAM64A,RCBTB2,MATN2,ITPR1,CSGALNACT1,AURKA,CENPE,NDE1,CCNB2,USP16 |
| 6.164e-14 | -30.42 | ovary | COSMIC cancer mutations | ovary | 15550 | 2372 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,MGST2,KIAA1147,RBM23,MUC16,ENPP5,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,BHLHE41,AIM1,MSH2,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,PLEKHF1,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,CAMK2G,IGDCC4,MLEC,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,TBC1D4,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MMD,ZNF84,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,TMPRSS4,GNB2,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,VAMP3,FURIN,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,OCLN,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,CDKN2C,NAPG,MUC4,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,NQO1,LFNG,CD82,APOO,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,TRAF2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,PDCD10,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,PRKAA1,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,REPS2,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,TMEM221,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ECI1,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,C17orf75,SHROOM2,JAK3,COL16A1,DRD1,LMO7,CCNE2,HDAC11,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,ADRBK1,TAF1B,LLGL2,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,CYP2J2,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,ADAM15,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,CCNL1,SLC7A2,LPIN3,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,PTGFRN,STK17B,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,ADIPOR1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,POLD3,MAP1B,KLHL2,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM |
| 6.811e-14 | -30.32 | HELLER_HDAC_TARGETS_UP | MSigDB lists | HELLER_HDAC_TARGETS_UP | 299 | 94 | 17758 | 2588 |
SORBS1,AGRN,DLGAP5,EPAS1,AASS,GMPR,IL13RA1,PDGFRL,BAIAP3,MICALL2,SEPT4,APLP2,CYP1A1,LRRC6,DNM2,BCL6,IFIT1,PIK3CD,CTTN,CDKN2D,HSPA2,GM2A,LAMP3,CPD,ING1,S100A4,CDC20,SAT1,PTGER4,PRKAR2B,CCNF,H2AFV,POR,ATP13A2,HPSE,ANKRD6,PLK2,STAT1,MAOA,SERPINI1,NRGN,GRN,KLF2,CDKN1C,CHCHD7,ITGA6,ZCCHC24,BLVRB,SDC4,JAG2,GPSM2,SBF1,SEPP1,BMP2K,H1FX,SCML1,SNTA1,TOP2A,GNS,RNF128,FAM20C,LLGL2,FDXR,SGK3,RUNDC3B,CD9,H2AFY,ADAM15,TSPAN13,NCAM1,TTLL1,NCOA2,HES1,CRIP2,CXorf57,HMG20B,KIAA1109,MAPK8IP1,GLCE,MAPKAPK2,NCOA3,TIMP3,H1F0,DHRS2,ITGA7,CGREF1,WDR19,NR4A2,FHL1,CENPE,L1CAM,IFI6,CSRP2,DOCK9 |
| 8.182e-14 | -30.13 | GNF2_CDC2 | MSigDB lists | GNF2_CDC2 | 61 | 34 | 17758 | 2588 |
DLGAP5,HJURP,FOXM1,CKAP2,PTTG1,CDCA3,NDC80,CDCA8,FANCI,TOP2A,PCNA,CCNA2,PRC1,PLK4,SMC4,CKS2,HMMR,ZWINT,KIF20A,ASPM,CDC20,MYBL2,WHSC1,NUSAP1,CCNF,KIF11,CDK1,PRIM1,AURKA,CENPE,CCNB2,UBE2C,E2F8,MELK |
| 8.888e-14 | -30.05 | organelle part | cellular component | GO:0044422 | 8026 | 1351 | 17570 | 2579 |
IBTK,SLC25A13,PNPLA2,HEXB,RET,CCNO,TRAPPC8,TGOLN2,DPP8,SNX9,NPM2,NAPG,MUC4,UBE2T,DNM2,PPP1CA,WBP4,CPE,MGAT5,DSTN,UXT,KDELR3,TFAP2C,PRKAR2B,GINS4,LCP1,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,HSPB1,STARD13,ANXA11,NXT2,SCN5A,GGA1,SEC61G,RAB23,COX6C,FAM21C,MARCH8,FLII,RAC2,ZCCHC17,FRY,ATP5H,FLRT3,RANBP1,FBXL14,PCYOX1,SLAIN2,CADPS2,USP1,MYDGF,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,PPP6R1,MCCC2,REC8,MAPKAPK3,PYM1,ERO1A,FHL2,KIF20B,ELK1,NPHP3,GOLT1A,GNA11,PSMA4,SFXN5,FNTA,ETS2,DGAT2,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,DMPK,TPRN,LFNG,APOO,C5orf30,MAPK4,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,XYLT2,ZNF365,MYT1,SNX10,ETV4,MX1,SNX8,SEC61B,ERMP1,COL6A2,AGPS,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,GTF2A2,COX20,GABARAPL1,PDLIM3,CCNB3,SHROOM3,WFS1,PNPLA6,SLC25A30,MAPK12,MZT1,HSP90B1,GCAT,CKAP2,BACE1,TRAF2,DCAF7,ESRP1,BIK,SDC4,HABP4,FLOT1,CTSZ,IFT27,SLC25A43,NFAT5,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,GPC3,MGAT4A,FAM20B,CST3,TUBGCP6,KLC3,BAX,RAG1,MED22,PARP9,ACBD5,PLSCR1,TACC1,PIK3R1,MRS2,UBE2A,AK4,RAB3IP,LDLRAP1,RPL12,PROM1,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,NR4A3,SSNA1,CMPK2,WDR45B,SRSF9,ACOT7,PHC1,EPAS1,ARFGEF1,LMCD1,NDRG2,DNAJB11,NENF,ITPR2,MGAT5B,SPTB,FANCI,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,NPNT,P4HB,ARL1,PSMC2,SLC44A1,ABCA2,SCARA3,SMAGP,PLK1,THRB,KRT80,STAU2,CBX6,NFE2L1,CKAP2L,ARFRP1,EAF2,DZIP1L,KDM4D,HS6ST1,PLEKHG6,AGPAT2,KLF12,ZNF367,KPNA2,MYL12B,RRAGD,RUNX2,LMTK3,USH1C,HJURP,LGALS3,FXYD3,PSMD7,RAB6A,B4GALNT1,MYO5C,TIMP1,KIF13B,TBCD,SLC30A6,SELK,FAR2,WNT3A,MPHOSPH9,CKAP4,MGAT4B,EMC2,SCRIB,PDK3,BCL2L13,CDK5R1,C18orf8,FA2H,COL13A1,PHLPP2,P4HA3,ZDHHC7,PLD1,AKIP1,CCNB2,USP43,RAD21,HOXB7,TP53,P2RX7,RHPN2,BAHD1,STIL,PCBP1,EMP2,BCAP31,TTC21B,PDGFA,KMT5C,WDR44,TACC2,BCL6,PLK4,VAT1,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,DAG1,ATP13A2,PTGS2,TAPBP,IDE,RBL1,STK38,MAOA,CHMP4B,XRCC3,IRF7,ST3GAL1,FAM134B,ARFGEF3,CTDSP1,BIN1,CMAS,PINK1,TAB3,CTSB,SCD5,MCTP2,CDCA8,ERCC6L,ERI2,GTF3A,HMGN3,LBR,AIP,PARM1,VPS26A,DNAJB9,H1FX,FZD6,M6PR,ZDHHC21,TBC1D31,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,ALDH7A1,HMGCL,GCNT1,P2RX4,HES1,RHOA,HMGN5,GUSB,PLAUR,PRICKLE1,MAML2,COL7A1,BBS2,TXNDC11,BCL10,DDX23,NEIL3,FGF18,E2F1,SH3BGRL2,PTGES,HIPK3,ZBTB33,GOLGB1,LAMP1,SLC35D2,TXN,PNISR,SSH1,HSPG2,CUL1,PSME1,SEPT4,PJA2,OAT,PICK1,SLC9A7,HELZ2,CYP1A1,STIM1,OSBPL3,POLL,IRF2,SNX16,HYLS1,MARCH2,ZBTB18,SPATA18,CDYL,BNIP3L,SLC35C1,KIF13A,POR,RAB2B,PRIM1,PPP2R4,CCDC97,RECQL,SCOC,TMEM55B,AKAP17A,TXNDC9,PSIP1,SH3RF2,CALR,DOPEY2,ZNRF2,RPL39,VASN,MSH2,TPST1,CACNA1D,GPR161,PIGC,GID8,PRODH,GCC2,CEP89,LPGAT1,CALM1,WHSC1,ATP8B3,ANTXR1,JADE2,NFIB,PLEKHH2,FAM64A,FAAH,WDR19,AGBL5,PIAS2,FAM83D,ARAP1,APPL2,SFMBT1,CABIN1,SAMD8,ZBTB34,PLIN3,HOOK1,EHD1,SPRED1,KIF3C,DLGAP5,TCTN2,THRA,CERCAM,NDRG1,CCDC110,ATP2C2,BCL2L1,FLT3,CYP39A1,ZFYVE9,CD46,CCNA2,ACAP2,RNASEH2A,PDE4D,OSBPL7,TSPAN1,FLOT2,MED30,ATG4D,DOCK4,COG2,FOXJ2,UTRN,CLSTN1,KIF1C,RAD17,PYGO1,PKMYT1,B3GALNT2,ITPR3,TRIQK,ATP10D,CEP162,ZMPSTE24,DDOST,ACAD10,TRIOBP,SLC27A3,CBX7,COBL,PRKAR1A,DEPDC1,CENPI,EPS8,NES,CBLL1,PLD2,FBXO6,SPDL1,DNAH3,HLA-A,COX7A2,SLC25A36,CKAP5,FUT8,DRAM1,CD9,CITED2,MSH6,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,PAPD7,ZC3H11A,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,CRTC2,DCTN6,ACADSB,FGFR2,ERAP1,WDR62,FZD5,ESPL1,CCNC,FAF2,CRYM,MPP5,MAP1LC3B,SLC8B1,ERP29,ECI1,TRIM68,ZFYVE16,RAB15,CDKL5,SIVA1,CEP78,TRPC1,ASH2L,CTTN,MYRIP,STK35,LAMP3,CERS2,CYP1B1,CXXC5,CENPA,LAP3,ASXL1,ACBD3,MAN2A2,GPRC5B,HPSE,TDRD7,GLA,CHPT1,NRGN,NR2C2,PCSK5,LASP1,PPP1R12A,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,CES2,OCRL,COL6A1,SUCO,PRKCI,SRP54,HLA-C,ZRANB1,GAD1,ETV7,SNX7,TPGS2,ELK3,SPA17,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,INSR,UAP1,TMEM30A,RAB31,CTSA,SHROOM2,APOL2,COL16A1,RARG,DRD1,CCNE2,DYNLRB1,SORBS1,PAX6,HDAC11,SOD2,PDIA5,COL18A1,SAYSD1,PHLDA1,EXT2,SAP130,CYP4F11,COX14,KIF14,REEP1,ECE1,NFKB2,ETHE1,UPF3A,EBAG9,SEPHS1,CHP1,SOAT1,C3orf52,MRPS35,TMTC2,CDC25C,FANCE,CASP4,PDHX,HSF4,JADE1,ALDH5A1,STAT6,TLE1,SPTBN5,MAD2L1BP,KDELC2,GLIS3,FBLIM1,SH3D19,SHPRH,COL4A5,INTS8,HMGXB4,ITGA2B,HDAC9,TMEM63A,KIF5B,TOP2A,MZT2A,CARD8,TAF1B,LLGL2,A4GALT,TOX2,RRBP1,ZDHHC13,ACTA2,H2AFY,CLIP2,RPGR,SLC35A1,MYO5A,B3GALT6,CFAP46,SYBU,RC3H2,RGCC,RUNX3,LEMD2,CTSL,CASP7,RND3,TRIM69,CTSV,RAP2C,CSGALNACT1,ARRB1,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,DOC2A,ACACB,TRIM24,IL15RA,ADD1,AASS,MRPS15,DNAJC3,SMARCAL1,FBXO2,XIAP,DHX8,CNTROB,MORF4L2,SYTL4,KIF26A,BARD1,PHF1,TP73,DAPK2,CALM2,WEE1,ZYX,RGS12,AP1M2,PSMD1,PQLC2,DNAH6,CYP2S1,CABP1,RDH14,FUT1,TUBG1,ACOX2,APOBEC3G,ODF2L,ERAP2,TUBA4A,VPS11,SMARCA2,SPEF2,TNIP1,SPRTN,MTRF1L,LOXL2,ICMT,MYOM1,CYP4F3,COL12A1,CAMK2N2,WDR11,DNM1L,LIMK1,MYLK,MAP3K11,MRPS28,ARF6,PDPR,ALDH6A1,FAM169A,NUAK1,CYP2J2,SOX9,SLC36A4,LMNA,GNS,DNPEP,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,NAGPA,UFD1L,KIF20A,SALL4,STAT4,MYBL2,PLS1,SRSF5,ILK,MEST,TP53INP2,SPTLC2,RHOB,DCP2,CYB5A,DHX32,NCOA3,SCARB2,HTT,TIMM8A,SETD3,ITPR1,AURKA,DYSF,MDH1,ALG2,B4GAT1,NDE1,ARPC2,RPS6KA3,MTM1,CCDC109B,GRHL2,TUBB4B,GALNT12,ACTR8,ETNK1,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,KTN1,CDS1,CCND1,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,RNF169,CAMSAP3,PSRC1,NRBF2,FZD4,CYS1,SYNE2,NUSAP1,CDCA2,PXYLP1,RAB38,PEX5,STX10,SLC9A6,WWTR1,TRABD2A,PDXK,RGS14,GEN1,ARNT,TTC8,TAOK2,MAN1A2,RASSF7,PDIA3,GMCL1,PKN1,NUCB2,TMA16,ETS1,NEO1,PDIA4,DTX3L,CAPN2,ANK1,ADD3,IRAK1,CTSC,ARSG,ANKS1B,ALG13,CALD1,FDXR,PLEKHF1,TMBIM6,ECI2,MAPK11,AK3,ITM2C,TPCN1,S100A6,TMX1,CRTAP,MOB4,LCA5,FMN1,BCL9,ELOVL3,EIF5A2,PLEKHA7,FAM109A,SKA1,GALNT3,NR1D2,ATXN7L3,ARFGAP3,HMGA1,CENPE,NUP37,USF2,FOXA1,MYL9,UNC93B1,AGRN,CUL4B,EPHA4,SUDS3,NDC80,MCCC1,CDIPT,HDAC6,PDGFB,NUP62CL,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,PXMP4,TRAM1,NEB,CCDC38,PCGF5,ING1,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,RHEB,OPTN,DPYSL3,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,TTC9,PIEZO1,POMT1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,ASAH1,RACGAP1,B4GALT4,DHRS3,PGAP1,SSX2IP,CORO1B,RB1,DAZAP1,GATA2,PAK2,MDFIC,TMEM8A,ALDH3A2,PSMA5,C9orf9,CYP26B1,CHSY3,MRPS33,SPATA13,KBTBD8,TCF7,ZDHHC3,G2E3,SMN1,MOSPD3,EPN3,MAPKAPK2,COQ10A,H1F0,MFSD2A,TMEM120A,CTBP1,NF2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,CCNL1,FAM198B,LPIN3,CYP26A1,SDF4,PER2,ATP6V0B,N4BP3,EGLN3,MINPP1,FAR1,GM2A,SIRT1,CPD,EVA1A,TCEB2,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,PSMD3,RPL22,LTA4H,AIFM3,NDST3,POMGNT2,CNEP1R1,ZC3HC1,COPG1,GSDMD,MAN2B2,COL9A3,GOLIM4,PACSIN2,TRAPPC10,CD63,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,CCDC92,CEP97,SLC35B4,BUB1,ABCD1,KLF9,HEXIM2,CAMK2G,MLEC,PSMB4,NR3C1,IFITM3,AMFR,LITAF,PPARA,CARD19,FXR2,AKAP3,FNDC3A,BCAR1,MAPK8IP1,FUCA1,SERPINA1,CDCA7L,NMI,PGRMC1,PPP2R3C,PKD2,ACADM,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,CFAP74,GAA,ATP8A1,FAM129B,KLC2,TAP1,GATA3,CCNB1,FAM101B,RIC1,CENPN,NCS1,CHST2,RGS3,STEAP2,PACSIN1,TFG,LAMP2,LOC81691,KIFC2,SNTB2,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SLC25A5,ULK2,SGPP1,AHRR,SFXN1,KDSR,SLC25A4,AREG,PLK2,GNPTAB,FAM110C,SARAF,TRAF5,RTN3,DLAT,MRPL44,HLA-E,DGKQ,SLC25A27,KIF23,NDUFA4,NOTCH2,SLC1A3,KIAA1161,BMP2K,MECOM,SNX18,NECAB3,BDH1,SORL1,PIKFYVE,CTSD,TMED2,EEF1D,FAM69A,DNAI1,FADS2,QSOX1,B3GNT7,PMPCB,DDB2,MMD,B9D2,VEZT,KDM3A,DGKH,PRKAG2,NR4A2,MAP3K5,NRBP1,IRF1,PLA2G4A,ELK4,SLC2A4,CEP70,ARMCX3,TRIP10,NLRX1,RPS6KA1,SUZ12,IQGAP1,SNN,AIFM2,GNB2,MNS1,SLC25A35,CYHR1,CDKN1B,TNPO2,LGMN,NR2C1,TMBIM1,GPX4,MYO5B,CDKN2AIP,SEC23A,TMEM43,CAPN6,DMTN,LYRM1,TEP1,COX11,SLC11A2,H2AFV,SP4,NIN,FYN,ZNF641,PPP2R5A,STK26,CFAP45,STAT1,PPP1CB,SLC27A1,RAB29,KLF5,HS3ST3B1,B4GALT3,NR3C2,MRPS9,ATP9A,SPR,TEAD3,AKIRIN1,FAM111A,PHF7,OXCT1,PPP1R10,PTEN,MGAT1,CENPJ,PRC1,ATP8B1,SLC44A2,ERCC2,MAP3K7,CNPY3,GFI1,SPRY2,NCOA2,SMC4,PCCB,CASK,MPP1,PARP4,FURIN,VAMP3,C1GALT1C1,GPLD1,NUCB1,CTNS,PRDX3,SLC25A40,CSTF2,GPER1,ARSB,NCAPG2,SLC25A38,ESYT2,JARID2,CASP3,CPT2,UBE2Z,TAF6L,KIF2C,TMC1,SH3KBP1,TSEN34,ABCD4,CHPF,MAGOHB,GRHL1,ZCCHC12,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,ANKRD12,SUN3,KIF22,RAB20,RP2,MYH14,NFU1,TECR,RASGRP1,ATL1,SOD1,TRIM8,SYNE3,FOPNL,MRPS18A,PTGFRN,MRPS36,TCN2,NEIL1,TRIM45,IARS2,RAP1GAP,PPP2R5D,PSMC1,STARD3NL,PIFO,PEX6,ELOVL7,KNTC1,ACAD8,LRIF1,HP1BP3,KDELR1,OXR1,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,FECH,GNAS,TSC1,NUDT16,PLPP3,UTP14C,CDCA5,PAPD5,KIF12,PROM2,GAS2L1,SLC25A24,SPC25,IL15,PSME2,SLC2A8,MORC4,ZMYND10,MICALL2,LRRC45,SLC25A48,SS18,SETDB2,SMO,STEAP3,RPN2,PDIA6,HSPA2,TAF5,KREMEN2,SLC39A8,OSTM1,AP5M1,ERBB2IP,DUSP4,SNAPC2,BFSP1,PEX2,CANT1,CYP2U1,SGOL1,REEP4,CBX4,ANXA3,CDS2,SORT1,POC1B,JKAMP,POMGNT1,SAC3D1,IRF2BPL,SNX13,GALNS,KIAA0319,CKS1B,BRD7,SYPL1,SUN2,RAB3B,CENPC,NR4A1,ASPM,OGDHL,POLD3,MPV17L2,SPAG1,MAP1B,HLA-B,MARC1,HNRNPH2,DHRS2,UBE2D2,TADA2B,GLB1,HOXB13,GEM,ATP6V1C1,SOX8,SNPH |
| 9.639e-14 | -29.97 | cell projection organization | biological process | GO:0030030 | 1206 | 273 | 16441 | 2455 |
CFAP74,AK7,CCNO,GATA3,NRG2,PSME1,PLXNA1,PICK1,CALM2,WEE1,PSMD1,DNM2,PACSIN1,TIAM1,DNAAF3,SPEF2,ULK2,ARF4,ARHGEF26,PLCG1,AREG,LIMK1,TRAF3IP1,MYLK,UNC5B,ITPKA,ARF6,FGD1,SCN5A,INPPL1,ITGA6,RAB23,RAC2,ITGA3,FRY,MEGF8,FLRT3,PRKG1,CACNA1D,NCAM1,TTLL1,NUP85,DNAI1,B9D2,CEP89,CALM1,ANO6,KIF20B,EPHA1,NPHP3,ILK,DPYSL4,PSMA4,NFIB,STX3,RHOB,RASA1,PTPRF,SEMA4D,MATN2,WDR19,FGD6,CLMN,AURKA,NR4A2,EFNA1,B4GAT1,CFAP20,ARPC2,TRPC3,RPS6KA3,EHD1,SPRED1,TCTN2,RPS6KA1,IQGAP1,C5orf30,MNS1,CDH1,DACT1,DAB2IP,ACSL4,EPHB4,DLG3,RASGEF1A,ETV4,SNX10,SEMA3B,CAMSAP3,COL6A2,PRKCQ,SLC11A2,TANC1,ALCAM,CEP162,EPHA10,IRS2,FYN,JAK1,STK26,SLC9A6,WWTR1,NRG1,KLF5,COBL,ATMIN,TTC8,WASF3,CTHRC1,FARP1,SDC4,FLOT1,NES,PLPPR4,IFT27,FGF19,EFNB1,NEO1,RND1,ANK1,IGSF9,PTEN,ERBB3,S100A6,FARP2,RASGRF1,LCA5,ARHGEF28,B3GNT2,FMN1,RAPGEF2,GRIN1,EMP3,RAB3IP,YES1,ABLIM2,CNTNAP1,FGFR2,RYK,NR4A3,SSNA1,GRIN2D,ITGAV,RGMA,MYL9,EMX1,UGT8,AGRN,EPHA4,CUL4B,ARFGEF1,PDGFB,CACNB4,SPTB,RPS6KA2,LRRC6,SHC3,DPYSL2,PSMC2,CAPG,DLG1,TRPC1,NTN4,MYH14,CTTN,BTBD3,RASGRP1,ATL1,SOD1,CELSR2,FOPNL,RNF165,EZR,DPYSL3,DZIP1L,MAP2,MYL12B,PSMC1,PIFO,USH1C,RASA2,PSMD7,CALM3,NCKAP1,CNTNAP2,DUSP5,SSX2IP,CORO1B,RB1,VASP,IGF1R,LRRN2,OCRL,PAK2,COL6A1,FXYD5,NTN1,WNT3A,CCDC88A,PSMA5,DPYSL5,RGMB,SPATA13,SCRIB,NUBP1,RANBP9,CDK5R1,EGFR,TSC1,ONECUT1,PVRL2,PITPNA,JAK3,SEMA3A,KLF7,PSME2,ERBB2,P2RX7,RASGRP3,ZMYND10,MICALL2,EMP2,STIL,TTC21B,PDGFA,ARTN,FRYL,FRS3,BAG4,AKT1,MYL12A,DAG1,ARHGAP35,RTN4RL1,PSMD3,EFNA5,SPTBN5,PLXND1,LIFR,COL9A3,PACSIN2,ARHGEF11,POC1B,CIT,ARHGEF7,LRP4,PSMD10,COL4A5,NRP2,ITGA2B,GBX2,KIF5B,CEP97,CDK16,BMP7,SGK1,RPGR,CAMK2G,RHOA,PSMB4,CFAP46,STMN3,BBS2,SPAG1,MAP1B,FAT4,FGF18,RAP2C,PGRMC1,CEP41,L1CAM,NGEF,ARHGEF4 |
| 9.692e-14 | -29.96 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | 690 | 173 | 17758 | 2588 |
CCNI,HECA,SSH1,TSC22D3,CUL4B,RET,TAP1,XIAP,IL18,MPP5,F11R,ITPR2,MORF4L2,MAP1LC3B,TFAP2E,ASPHD2,SIPA1L2,ENTPD4,STIM1,METTL7A,DPYSL2,CAPG,PIK3CA,TMEM143,DUSP10,SNX16,CTTN,PTPRE,DDX59,CD55,TRIM8,NFE2L1,BNIP3L,IDH1,RAB2B,PLCH1,CARHSP1,MID1IP1,PTER,RAB11FIP1,SERPINB6,MAFF,INPPL1,CDK17,ALDH6A1,HLA-E,ZCCHC24,HLA-F,ETV5,B4GALT4,IL18R1,TTYH3,PSIP1,DUSP5,BMP2K,GNS,WDFY1,SLC16A6,C10orf54,NCEH1,C9orf9,GFPT1,DDB2,KIAA1841,IFIT3,NPHP3,NCOA3,HTT,ITPR1,STK39,NDE1,SERPINB1,CBX5,RNF146,EHD1,SLC25A24,ARMCX3,NQO1,S100A11,CAST,FTH1,TMEM170B,PHLDA1,MXD1,UHRF1BP1L,RCN1,SP100,LMO4,BCL6,TWIST1,PDE4D,OSBPL7,SCYL3,CTH,TIMP2,FOXJ2,UTRN,DUSP4,CD40,MYL12A,DNAJC10,FYN,ZNF641,JAK1,C19orf66,CDK19,TRIOBP,ZBTB6,AKNA,RGS14,ST3GAL1,CBX4,FAM134B,OTUD5,ANXA3,CPEB4,ARHGEF7,BLVRB,GNE,FLOT1,MIER3,TGFBR1,TRIB2,ETS1,ARHGEF40,NFAT5,H1FX,DNAJB9,HLA-A,SLC25A36,HDAC9,CCDC92,CAPN2,IRF2BPL,FAM111A,E2F7,TMEM87B,CEP97,GNB5,LLGL2,FAM63A,ZNF230,HMGCL,HSPA13,KLF9,SGCB,SYK,MYO5A,P2RX4,TGIF1,ARAP2,PLSCR1,NR3C1,RAPGEF2,DENND1B,RAB3IP,SNTB1,SKA1,BSDC1,KLHL2,CRTC2,BTG1,RCBTB2,SLC25A40,CCDC69,ARFGAP3,ERAP1,PKD2,PPP2R3C,ITGAV,CPEB2,ARHGEF9,GOLGB1 |
| 1.006e-13 | -29.93 | large_intestine-colon-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma-adenocarcinoma | 17299 | 2565 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,RHBDL3,PTTG1,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,GPR107,CAPN12,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.132e-13 | -29.81 | colon | COSMIC cancer mutations | colon | 17300 | 2565 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,RHBDL3,PTTG1,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,GPR107,CAPN12,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.193e-13 | -29.76 | protein modification process | biological process | GO:0036211 | 2835 | 554 | 16441 | 2455 |
TRIM24,TRIM5,RET,XIAP,FBXO2,NRG2,IL18,MORF4L2,BARD1,SPSB1,GRM5,CALM2,DAPK2,WEE1,PSMD1,TGFBR3,MUC4,UBE2T,FUT1,CRY2,PPP1CA,PIK3CD,TIPARP,CPE,MGAT5,NEK4,FBXL16,RNF11,LOXL2,ICMT,RNF19B,ARF4,PIAS3,LIMK1,MYLK,NOD2,MAP3K11,HDAC1,RNASEL,ITPKA,GAB1,NUAK1,SOX9,ZNRF3,MERTK,RABGGTA,ATG4A,MARCH8,FBXO7,NEK2,FBXL14,MAP3K9,USP38,USP1,ALPK1,STT3B,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,TTLL1,PPP6R1,NAGPA,MAPKAPK3,STAT4,ERO1A,SHARPIN,ELK1,ILK,PSMA4,STK17A,PTPRF,NCOA3,FNTA,MTFMT,SETD3,TEX30,AURKA,STK39,B4GAT1,ALG2,CFAP20,NUP58,RPS6KA3,RUSC1,EGLN1,DMPK,MTM1,GALNT12,INPP5D,WDTC1,TESK2,MAPK4,GRK6,PRKACA,CCND1,MUC16,RNF220,SP100,RASGEF1A,RNF169,SSH3,RIPK2,PTPN9,XRCC6BP1,IRS2,CDK19,AXL,WWTR1,TRABD2A,MAPK12,TAOK2,MAN1A2,DCAF7,TRAF2,CCM2,PDIA3,CTSZ,PKN1,TSPAN17,DTX3L,FUT2,IRAK1,CTSC,ARSG,ALG13,MGAT4A,WWP1,MAPK11,RAG1,CRTAP,RAPGEF2,PIK3R1,DUSP23,EIF5A2,NUB1,GRIN1,UBE2A,PIM3,NEURL1B,TXK,GALNT3,DCAF10,BTG1,PLOD2,ATXN7L3,ACVRL1,DBI,PPM1H,ITGAV,NUP37,WDR45B,PHC1,UNKL,TNK1,TRIM2,PPM1J,CUL4B,EPHA4,SUDS3,MGAT5B,HDAC6,PDGFB,PIGL,SPTB,NUP210,RPS6KA2,SHC3,P4HB,MKRN3,PSMC2,PASK,DUSP10,PLK1,MARK1,PTPN18,PRKRA,CDK1,VCP,KDM4D,TRIM9,MSL1,WIPI1,P4HA2,DOLPP1,TTC9,POMT1,PRKAA2,LMTK3,RASA2,UBASH3B,PSMD7,ADCK5,RAB6A,B4GALT4,PGAP1,B4GALNT1,BMP2,UBE2Q2,IGF1R,PAK2,MDFIC,PIM1,PSMA5,USP31,TESK1,MGAT4B,KBTBD8,STRADB,EIF2AK1,PDK3,ZDHHC3,G2E3,NMT2,CDK5R1,MAPKAPK2,PHLPP2,KBTBD2,P4HA3,ZDHHC7,CTBP1,RNF146,USP43,RAD21,P3H2,CTDSPL,ERBB2,P2RX7,RASGRP3,KBTBD11,PER2,CDK14,PDGFA,KMT5C,PPME1,ZDHHC23,PLK4,LMAN1,EGLN3,CTDSP2,CTH,SIRT1,PPIF,TCEB2,AKT1,CDC20,PTGER4,PTPRJ,ATP1A1,PSMD3,PTK7,STK38,ST3GAL1,POMGNT2,ZC3HC1,CTDSP1,MAN2B2,CMAS,PINK1,DYRK3,TRAPPC10,KLHL13,TAB3,GNE,PSMD10,PPP2R3A,ZDHHC21,CDK16,UBE2J1,SGK1,TRIM21,BUB1,SYK,CAMK2G,GCNT1,DUSP1,MLEC,PSMB4,AMFR,PLAUR,COL7A1,PELI3,MAPK8IP1,USP6,PRDX4,FUCA1,SERPINA1,SCG2,FGF18,UBE2C,HIPK3,ACVR1,SSH1,CUL1,PSME1,NANS,CAMK1D,PJA2,CCNB1,PICK1,ASPHD2,PAK6,PALD1,IL31RA,PIK3CA,MARCH2,TFG,METAP2,ACVR1C,PBK,CDYL,GALNT7,SLC17A5,AURKB,MCFD2,CCNF,POR,ULK2,SGPP1,AREG,GNPTAB,SH2D3C,PLK2,PPP2R4,PRDM5,MAPK13,TRAF5,CDK17,DHPS,PRKAA1,HERC6,TNFRSF19,BMP2K,SH3RF2,CALR,ZNRF2,PPP4R1,OPN3,PRKG1,ADCK2,DAPK1,TPST1,MAST4,TMED2,TRAK2,SOCS5,GFPT1,PIGC,B3GNT7,DDB2,MMD,CALM1,PTPRH,WHSC1,EPHA1,JADE2,KDM3A,FBXO10,RASA1,MMP15,PRKAG2,PELI2,CSNK1G1,ZDHHC20,PIAS2,AGBL5,CDK18,MAP3K5,IFIH1,NRBP1,ELK4,SPRED1,DLGAP5,SUZ12,RPS6KA1,RNF182,DDR1,FLT3,ART5,EPM2A,DOK4,FICD,DAB2IP,EPHB4,PHKA2,ATG4D,SEC23A,PRKCQ,PKMYT1,CBL,B3GALNT2,ASB13,EPHA10,FYN,DDOST,JAK1,STK26,TRIOBP,KIAA1804,PPP1CB,NRG1,MLKL,B4GALT3,AREL1,OTUD5,CDCA3,HERC5,CBLL1,FBXO6,FGF19,WWP2,RNF128,MGAT1,PTEN,FUT8,SGK3,ERBB3,ERCC2,MAP3K7,TRIM62,NCOA2,RASGRF1,B3GNT2,CASK,FURIN,PARP4,FBXO9,C1GALT1C1,UBAC1,YES1,FOS,ARSK,CRTC2,PRDX3,FGFR2,RYK,GRIN2D,LRRK1,ARSB,MELK,USP16,CCNC,CAMKK1,UBE2Z,UBE2Q1,TAF6L,TRIM68,ADPRHL1,CDKL5,DLG1,ASH2L,PTPRE,STK35,RASGRP1,TRIM8,ASXL1,USP18,ITCH,RNF165,ROR1,STK17B,ADRBK2,MAN2A2,FASTKD1,UEVLD,CAB39,PPP2R5D,PSMC1,CPPED1,PPP1R12A,ASB9,ASL,CALM3,TEC,PHLPP1,ADAMTSL4,DUSP5,B3GALNT1,OTUD1,FAM20C,PRKCI,NPTN,ZRANB1,GAD1,MDFI,GYLTL1B,PDIK1L,EGFR,INSR,UAP1,PLPP3,DCUN1D1,ALPK3,CTSA,YOD1,JAK3,FBXW5,LMO7,PAX6,IL15,PSME2,HDAC11,EXT2,SAP130,SETDB2,ZDHHC12,RPN2,LOXL1,F2R,SCYL3,SEPHS1,FRS3,MAP3K3,TAF5,PTPRU,DUSP4,CDC25C,MAP3K6,SOCS3,HSF4,JADE1,PEX2,SPTBN5,ABCA1,CBX4,CIT,SHPRH,TGFBR1,NOTUM,TRIB2,SBF1,POMGNT1,HDAC9,ADRBK1,A4GALT,TRIM3,IQGAP3,SLC35A1,B3GALT6,RAB3B,DCAF6,RC3H2,RUNX3,KLHL2,TRIM69,DTX4,UBE2D2,TADA2B,ARRB1,OTUB2,GLB1,CEP41,PLOD3 |
| 1.193e-13 | -29.76 | cellular protein modification process | biological process | GO:0006464 | 2835 | 554 | 16441 | 2455 |
TRIM24,TRIM5,RET,XIAP,FBXO2,NRG2,IL18,MORF4L2,BARD1,SPSB1,GRM5,CALM2,DAPK2,WEE1,PSMD1,TGFBR3,MUC4,UBE2T,FUT1,CRY2,PPP1CA,PIK3CD,TIPARP,CPE,MGAT5,NEK4,FBXL16,RNF11,LOXL2,ICMT,RNF19B,ARF4,PIAS3,LIMK1,MYLK,NOD2,MAP3K11,HDAC1,RNASEL,ITPKA,GAB1,NUAK1,SOX9,ZNRF3,MERTK,RABGGTA,ATG4A,MARCH8,FBXO7,NEK2,FBXL14,MAP3K9,USP38,USP1,ALPK1,STT3B,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,TTLL1,PPP6R1,NAGPA,MAPKAPK3,STAT4,ERO1A,SHARPIN,ELK1,ILK,PSMA4,STK17A,PTPRF,NCOA3,FNTA,MTFMT,SETD3,TEX30,AURKA,STK39,B4GAT1,ALG2,CFAP20,NUP58,RPS6KA3,RUSC1,EGLN1,DMPK,MTM1,GALNT12,INPP5D,WDTC1,TESK2,MAPK4,GRK6,PRKACA,CCND1,MUC16,RNF220,SP100,RASGEF1A,RNF169,SSH3,RIPK2,PTPN9,XRCC6BP1,IRS2,CDK19,AXL,WWTR1,TRABD2A,MAPK12,TAOK2,MAN1A2,DCAF7,TRAF2,CCM2,PDIA3,CTSZ,PKN1,TSPAN17,DTX3L,FUT2,IRAK1,CTSC,ARSG,ALG13,MGAT4A,WWP1,MAPK11,RAG1,CRTAP,RAPGEF2,PIK3R1,DUSP23,EIF5A2,NUB1,GRIN1,UBE2A,PIM3,NEURL1B,TXK,GALNT3,DCAF10,BTG1,PLOD2,ATXN7L3,ACVRL1,DBI,PPM1H,ITGAV,NUP37,WDR45B,PHC1,UNKL,TNK1,TRIM2,PPM1J,CUL4B,EPHA4,SUDS3,MGAT5B,HDAC6,PDGFB,PIGL,SPTB,NUP210,RPS6KA2,SHC3,P4HB,MKRN3,PSMC2,PASK,DUSP10,PLK1,MARK1,PTPN18,PRKRA,CDK1,VCP,KDM4D,TRIM9,MSL1,WIPI1,P4HA2,DOLPP1,TTC9,POMT1,PRKAA2,LMTK3,RASA2,UBASH3B,PSMD7,ADCK5,RAB6A,B4GALT4,PGAP1,B4GALNT1,BMP2,UBE2Q2,IGF1R,PAK2,MDFIC,PIM1,PSMA5,USP31,TESK1,MGAT4B,KBTBD8,STRADB,EIF2AK1,PDK3,ZDHHC3,G2E3,NMT2,CDK5R1,MAPKAPK2,PHLPP2,KBTBD2,P4HA3,ZDHHC7,CTBP1,RNF146,USP43,RAD21,P3H2,CTDSPL,ERBB2,P2RX7,RASGRP3,KBTBD11,PER2,CDK14,PDGFA,KMT5C,PPME1,ZDHHC23,PLK4,LMAN1,EGLN3,CTDSP2,CTH,SIRT1,PPIF,TCEB2,AKT1,CDC20,PTGER4,PTPRJ,ATP1A1,PSMD3,PTK7,STK38,ST3GAL1,POMGNT2,ZC3HC1,CTDSP1,MAN2B2,CMAS,PINK1,DYRK3,TRAPPC10,KLHL13,TAB3,GNE,PSMD10,PPP2R3A,ZDHHC21,CDK16,UBE2J1,SGK1,TRIM21,BUB1,SYK,CAMK2G,GCNT1,DUSP1,MLEC,PSMB4,AMFR,PLAUR,COL7A1,PELI3,MAPK8IP1,USP6,PRDX4,FUCA1,SERPINA1,SCG2,FGF18,UBE2C,HIPK3,ACVR1,SSH1,CUL1,PSME1,NANS,CAMK1D,PJA2,CCNB1,PICK1,ASPHD2,PAK6,PALD1,IL31RA,PIK3CA,MARCH2,TFG,METAP2,ACVR1C,PBK,CDYL,GALNT7,SLC17A5,AURKB,MCFD2,CCNF,POR,ULK2,SGPP1,AREG,GNPTAB,SH2D3C,PLK2,PPP2R4,PRDM5,MAPK13,TRAF5,CDK17,DHPS,PRKAA1,HERC6,TNFRSF19,BMP2K,SH3RF2,CALR,ZNRF2,PPP4R1,OPN3,PRKG1,ADCK2,DAPK1,TPST1,MAST4,TMED2,TRAK2,SOCS5,GFPT1,PIGC,B3GNT7,DDB2,MMD,CALM1,PTPRH,WHSC1,EPHA1,JADE2,KDM3A,FBXO10,RASA1,MMP15,PRKAG2,PELI2,CSNK1G1,ZDHHC20,PIAS2,AGBL5,CDK18,MAP3K5,IFIH1,NRBP1,ELK4,SPRED1,DLGAP5,SUZ12,RPS6KA1,RNF182,DDR1,FLT3,ART5,EPM2A,DOK4,FICD,DAB2IP,EPHB4,PHKA2,ATG4D,SEC23A,PRKCQ,PKMYT1,CBL,B3GALNT2,ASB13,EPHA10,FYN,DDOST,JAK1,STK26,TRIOBP,KIAA1804,PPP1CB,NRG1,MLKL,B4GALT3,AREL1,OTUD5,CDCA3,HERC5,CBLL1,FBXO6,FGF19,WWP2,RNF128,MGAT1,PTEN,FUT8,SGK3,ERBB3,ERCC2,MAP3K7,TRIM62,NCOA2,RASGRF1,B3GNT2,CASK,FURIN,PARP4,FBXO9,C1GALT1C1,UBAC1,YES1,FOS,ARSK,CRTC2,PRDX3,FGFR2,RYK,GRIN2D,LRRK1,ARSB,MELK,USP16,CCNC,CAMKK1,UBE2Z,UBE2Q1,TAF6L,TRIM68,ADPRHL1,CDKL5,DLG1,ASH2L,PTPRE,STK35,RASGRP1,TRIM8,ASXL1,USP18,ITCH,RNF165,ROR1,STK17B,ADRBK2,MAN2A2,FASTKD1,UEVLD,CAB39,PPP2R5D,PSMC1,CPPED1,PPP1R12A,ASB9,ASL,CALM3,TEC,PHLPP1,ADAMTSL4,DUSP5,B3GALNT1,OTUD1,FAM20C,PRKCI,NPTN,ZRANB1,GAD1,MDFI,GYLTL1B,PDIK1L,EGFR,INSR,UAP1,PLPP3,DCUN1D1,ALPK3,CTSA,YOD1,JAK3,FBXW5,LMO7,PAX6,IL15,PSME2,HDAC11,EXT2,SAP130,SETDB2,ZDHHC12,RPN2,LOXL1,F2R,SCYL3,SEPHS1,FRS3,MAP3K3,TAF5,PTPRU,DUSP4,CDC25C,MAP3K6,SOCS3,HSF4,JADE1,PEX2,SPTBN5,ABCA1,CBX4,CIT,SHPRH,TGFBR1,NOTUM,TRIB2,SBF1,POMGNT1,HDAC9,ADRBK1,A4GALT,TRIM3,IQGAP3,SLC35A1,B3GALT6,RAB3B,DCAF6,RC3H2,RUNX3,KLHL2,TRIM69,DTX4,UBE2D2,TADA2B,ARRB1,OTUB2,GLB1,CEP41,PLOD3 |
| 1.646e-13 | -29.44 | PILON_KLF1_TARGETS_DN | MSigDB lists | PILON_KLF1_TARGETS_DN | 1896 | 387 | 17758 | 2588 |
HECA,IBTK,FAM160B1,MRPS15,DNAJC3,XIAP,SMARCAL1,CUL1,FAM102B,TRAPPC8,MORF4L2,FAM101B,CARD10,CMTM6,WEE1,KLF3,ATRNL1,PIK3CD,WBP4,TIAM1,LAMP2,TMEM68,PBK,CDYL,PIF1,GALNT7,SLC25A5,SPNS3,LCP1,SGPP1,PRIM1,SFXN1,KDSR,ANKRD10,PIAS3,GNPTAB,MAP3K11,HDAC1,RELL1,ARF6,ANXA11,RECQL,MRPL44,CDK17,FRMD4A,ALDH6A1,ITGA6,ADO,NOTCH2,COX6C,TFAP4,FRY,ZNRF2,PAIP2B,SNX18,PPP4R1,PCYOX1,FBXL14,MSH2,SORL1,SLAIN2,USP1,STT3B,ZMYM1,MYLIP,FAM69A,KIF20A,B9D2,MAPKAPK3,LPGAT1,KCTD20,FAM133B,NPC2,CYFIP2,STX3,SCARB2,SERTAD2,FNTA,TIMM8A,DCK,C1orf21,ZDHHC20,ITPR1,MDH1,ZBTB34,MAP3K5,NDE1,SERPINB1,TMEM173,ARHGAP11A,PLA2G4A,ELK4,PAPSS2,S100A11,CERCAM,IQGAP1,CAST,RPS6KA1,C5orf30,KCTD12,NUF2,TMEM170B,FAM91A1,GRK6,TMEM19,REPS1,APPBP2,KIAA1147,UHRF1BP1L,APOBEC3B,ACAP2,RALB,PHKA2,AGPS,PTPN9,PANK1,VPS4B,NUSAP1,PKMYT1,ATP1B1,RAB38,AKR1E2,CBL,CMTM7,ZMPSTE24,NIN,ALDH3B1,FYN,PPP2R5A,CDK19,SLC9A6,SIPA1L1,STAT1,PPP1CB,PDXK,SLC25A30,ISOC1,MRPS9,MZT1,TNRC6C,CCM2,CBLL1,EFHD2,CTSZ,GMCL1,IFT27,ETS1,TIPRL,AKIRIN1,DTX3L,FAM111A,SLC25A45,ZFX,E2F7,ADD3,OXCT1,PTEN,CTSC,FUT8,CST3,FAM20B,SGK3,PRC1,SLC44A2,TMBIM6,TAGLN2,MAP3K7,CNOT6L,TPCN1,NCOA2,MSH6,PARP9,MOB4,ALDH2,PLSCR1,PAPD7,TACC1,BCL9,DENND1B,PIK3R1,UBE2A,VAMP3,DBR1,C1GALT1C1,DCTN6,LDLRAP1,PROM1,ATXN7L3,DBI,RIN3,PLA2G15,FAM3C,CSTF2,ERAP1,ITGAV,ARSB,MELK,ACOT7,DEF6,ESYT2,JARID2,CASP3,UNC93B1,ST13,ARFGEF1,TEX2,KIF2C,SH3KBP1,MAGOHB,NUP210,RPS6KA2,TM9SF2,DPYSL2,IMPAD1,ARL1,CAPG,AKR1B1,RP2,TRAM1,PTPRE,FGFR1OP2,PCGF5,ING1,PTPN18,CXXC5,HN1L,LAP3,ASXL1,ACBD3,ITCH,CKAP2L,ARHGDIB,ARFRP1,ERP44,ANLN,IDH1,ZBTB7B,LHFPL2,SESN1,STK17B,ADRBK2,RHEB,TCN2,MAN2A2,TMEM164,MSL1,CDCA4,AGPAT2,CAB39,MYL12B,NR2C2,LASP1,ARAP3,PPP1R2,LGALS3,RASA2,PDCL,ASAH1,RACGAP1,DOCK11,B4GALNT1,TNS3,IGF1R,RINL,GATA2,KCNN4,PAK2,TBCD,PRKCI,EXOC8,RFX5,C10orf54,ALDH3A2,MPHOSPH9,CKAP4,ABCC1,HP1BP3,ELK3,CORO2A,OXR1,HEATR5A,PRRC1,RANBP9,SLC6A6,KBTBD2,PAPD5,PRPS2,RAB31,PITPNA,ATP1B3,RNF146,SNX30,RAD21,SLC25A24,UGP2,TMX4,SDF4,TTC21B,SS18,SETDB2,EFR3A,PLCG2,PLK4,TMEM64,LMAN1,PDIA6,SCYL3,GM2A,EBAG9,SULF2,SOAT1,SIRT1,MAP3K3,TAF5,MBP,AKT1,FIGNL1,OSTM1,DOCK5,KCTD2,ATP13A2,DNAJC10,IDE,RBL1,BHLHB9,STK38,AKNA,ARHGAP4,CBX4,ANXA3,TM2D2,TRAPPC10,CIT,JKAMP,ERI2,ERCC6L,SELL,TGFBR1,TRIB2,LBR,HMGXB4,XPR1,VPS26A,ZNF212,TMEM63A,SNX13,SLC35B4,ZDHHC13,GTF2F2,H2AFY,IL17RA,CKS1B,BRD7,TRIM21,ABCD1,TSPAN13,MXD3,IQGAP3,SYK,CAMK2G,SYPL1,ADAM17,MLEC,NR3C1,GUSB,RC3H2,MBNL3,TRIM35,GGH,POLD3,BCL10,TMEM50B,SWAP70,CASP7,ZMYND19,NIPSNAP3A,NMI,RAP2C,UBE2D2,DTX4,PPP2R3C,ACADM,SPCS3,ZMIZ1,HIPK3,ZBTB33,CD33 |
| 1.811e-13 | -29.34 | protein kinase binding | molecular function | GO:0019901 | 511 | 139 | 16491 | 2452 |
IBTK,TRIM5,DNAJC3,CCNB1,PJA2,CACNB4,PICK1,NCS1,TP73,CDKN2C,CALM2,PCNA,ELMO2,SHC3,DPYSL2,ZFP36,IL31RA,DLG1,DNM2,PLK1,TNIP1,CASP9,EZR,PRKAR2B,RHEB,PLCG1,CAMK2N2,GPRC5B,MAP3K11,NOD2,PRKCDBP,ADIPOR1,HSPB1,PIFO,SCN5A,PPP1R12A,SOX9,CALM3,RACGAP1,KIF13B,FBXO7,PAK2,MSH2,MAPK7,CCDC88A,SOCS5,KIF20A,MAPKAPK3,CALM1,EPHA1,ILK,CDK5R1,MAPKAPK2,FNTA,PRKAG2,FAM83D,AURKA,STK39,MAP3K5,TOB1,RPS6KA3,TMEM173,FBXW5,CCNE2,SPRED1,PAX6,SORBS1,FOXM1,IQGAP1,TP53,PKP2,MAPK4,CCNL1,BCL2L1,PRKACA,EMP2,ARHGEF16,CCND1,CCNA2,DACT1,KIF14,PPME1,GYS1,DAB2IP,CDKN2D,SIRT1,DOCK4,AKT1,PFKFB2,UTRN,CDC25C,IRS2,PTPRJ,ATP1A1,CCNB3,STK38,PPP1CB,NRG1,MLKL,ZC3HC1,PRKAR1A,PINK1,TAOK2,TRAF2,ARHGEF7,LRP4,SDC4,PKN1,TRIB2,GSTP1,HDAC9,TOP2A,ADD3,PDCD10,PTEN,CENPJ,PRC1,H2AFY,ACTA2,SPRY2,SYK,PIK3R1,RGCC,BORA,KIF11,BCAR1,MAPK8IP1,BCL10,CDK5RAP1,CD8A,PRDX3,RAB11FIP2,ACVRL1,E2F1,NR4A3,ARRB1,ITGAV,FZD5,PKIA |
| 1.978e-13 | -29.25 | GTGCCTT,MIR-506 | MSigDB lists | GTGCCTT,MIR-506 | 690 | 172 | 17758 | 2588 |
FAF2,TMEM184B,FAM129B,PNPLA2,SH3KBP1,ARHGEF37,MITF,SERINC2,DNM2,MYRIP,STK35,CERS2,SERTAD4,RNF165,SLC17A5,PNKD,TYSND1,SGPP1,MDK,PGF,PI4K2B,TRAM2,FAM177A1,MID1IP1,P4HA2,MYLK,LRIG1,RAB11FIP1,ARRDC1,CTNND1,LZTS1,CAPN1,ANXA11,NR2C2,LRRFIP2,TBC1D1,ZCCHC24,FAM81A,PGAP1,TFAP4,ITGA3,FLRT3,FRAS1,PCYOX1,DAPK1,LIMCH1,USP38,USP1,PIM1,MAPK7,SLC12A2,C9orf72,SOCS5,QSOX1,ELK3,PIP4K2C,PDE5A,FAM133B,SPTLC2,TP53INP2,PDIK1L,C3orf58,CYB5A,GLCE,MAPKAPK2,SERTAD2,ITGA7,DGAT2,PCDH19,PITPNA,STK39,ALG2,FBXO27,RARG,NIPA1,IRF1,SPRED1,PAPSS2,UPF3B,RPS6KA1,IQGAP1,RALBP1,CTDSPL,MOCS1,C11orf84,ZNF687,WDR44,LMO4,DACT1,BCL6,VAT1,GYS1,STEAP3,RASGEF1A,OSBPL7,FLOT2,FAR1,CTDSP2,PPIF,CPD,CAPN6,FZD4,PTPN9,VPS4B,HTATIP2,DNAJB14,RAD17,RAB38,CBL,NFIX,ZMPSTE24,ATP1A1,RBL1,STK38,OVOL1,SLC27A1,ZBTB6,NR3C2,ABCA1,CMTM4,FAM134B,CTDSP1,RBM24,TRAPPC10,EPS8,SDC4,FLOT1,AES,TGFBR1,NKRF,JAG2,ZNF219,ARHGEF40,EFNB1,NFAT5,SIX4,NRP2,SLC9A2,SGPL1,HDAC9,IRF2BPL,SNTA1,RNF128,ANKS1B,MGAT4A,SLC44A2,SGK1,ABCD1,ITM2C,SYPL1,PGM1,MLEC,NR3C1,NR4A1,VAMP3,FURIN,C2orf69,LRRC1,FXR2,AIF1L,USP6,LEMD2,LDLRAP1,TWSG1,AMMECR1,NR4A3,FAM117A,SOX8,PLOD3,AHR,LRRC57,ESYT2 |
| 1.983e-13 | -29.25 | FORTSCHEGGER_PHF8_TARGETS_DN | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_DN | 732 | 180 | 17758 | 2588 |
TMEM184B,CUL4B,SUDS3,LMCD1,F11R,VASH1,OAT,ELMOD2,CMTM6,PAK6,SUSD2,NAPG,TGFBR3,ELMO2,METTL7A,IMPAD1,DPYSL2,TSPAN6,RGS3,OSBPL3,ARL1,PHTF1,CAPG,AOX1,ARNT2,RP2,MTMR11,TINAGL1,SCARA3,OLFML2A,KRT80,PCGF5,TRIM8,TNIP1,ARHGDIB,ROR1,ULK2,ARF4,OPTN,KDSR,PIAS3,TNS4,TMEM164,TRAM2,PI4K2B,WIPI1,GDE1,MYLK,CTNND1,NXT2,DDX58,NFKBIE,PPP1R12A,CHCHD7,ELOVL7,ASL,ABCG2,PDCL,C6orf106,SAMD9,PM20D2,C3orf18,TTYH3,AIM1L,RAC2,ITGA3,SPIN4,LYPD3,KCNN4,OCRL,MEGF8,COL6A1,DPYSL5,GFPT1,PLEKHA6,PRSS23,RGMB,CORO2A,PLS1,IFIT3,ILK,NFIB,DCP2,STK17A,SLC6A6,COQ10A,H1F0,PHLPP2,MATN2,RAB31,DYSF,YOD1,STK39,TMEM159,JAK3,IFIH1,COL16A1,TMEM173,EGLN1,EHD1,MFSD3,KIF3C,REPS2,NF2,CAST,CD82,BLCAP,BCL2L1,MICALL2,PHLDA1,TACC2,TAX1BP3,IFIT1,TMEM64,TMBIM1,RNF169,SEMA3B,MYO5B,SOAT1,GCA,SSH3,FIGNL1,S100A4,CYB5R2,C3orf52,PTGER4,KIF1C,KCTD2,MAP3K6,SNX12,AXL,SLC9A6,PPP1CB,MAOA,VSIG10,SLC27A1,RPL22,FAM134B,FBLIM1,MZT1,CPEB4,FAM189A2,IGFBP6,ENO2,PLEKHJ1,FRMD6,DCAF7,MAN1A2,RASSF7,PSMD10,PBX3,TGFBR1,XPR1,FAM111A,OXCT1,ITGB8,ALPP,FUT8,CD9,S100A6,NFE2L3,MOB4,CASK,DCAF6,TACC1,CTNNAL1,MPP1,EIF5A2,MYEOV,PLEKHA7,BCAR1,TMEM50B,TIMP3,CCDC6,DHRS2,AMMECR1,CDCA7L,FGF18,SPINT2,PTGES |
| 2.009e-13 | -29.24 | intracellular membrane-bounded organelle | cellular component | GO:0043231 | 10597 | 1721 | 17570 | 2579 |
HECA,IBTK,SLC25A13,PNPLA2,HEXB,RET,CCNO,TRAPPC8,TGOLN2,ISOC2,LACTB2,DPP8,SNX9,ZNF275,NPM2,CDKN2C,NAPG,MUC4,UBE2T,ATP13A3,DNM2,CRY2,PPP1CA,WBP4,TIPARP,CPE,MGAT5,UXT,TMEM98,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,GINS4,PIAS3,ENPP1,PLCG1,MID1IP1,CELF5,ATP7B,NOD2,HDAC1,RNASEL,HSPB1,STARD13,ANXA11,NXT2,SCN5A,GGA1,SEC61G,MTL5,RAB23,COX6C,FAM21C,MARCH8,TFAP4,FLII,RAC2,ZCCHC17,ATP5H,MEGF8,FLRT3,FBXO7,RANBP1,FBXL14,PCYOX1,CADPS2,USP1,MYDGF,ZMYM1,MAPK7,MOXD1,NUP85,PPP6R1,MCCC2,REC8,PQLC3,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,GOLT1A,PSMA4,GNA11,SFXN5,PLIN5,IL1R1,ETS2,APMAP,S100A5,DGAT2,STK39,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,DMPK,LFNG,APOO,PTTG1,MAPK4,MGST2,MVB12B,MOCS1,APPBP2,RCN1,RBM23,MUC16,CDH1,XYLT2,TAX1BP3,MYT1,SNX10,ETV4,MX1,SNX8,SEC61B,ERMP1,COL6A2,AGPS,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,GTF2A2,SNX12,TRIM7,ZNF618,COX20,EBF2,GABARAPL1,NFIX,CCNB3,CDK19,WFS1,PNPLA6,SLC25A30,ISOC1,MAPK12,HSP90B1,GCAT,BACE1,TRAF2,DCAF7,ESRP1,BIK,SDC4,HABP4,FLOT1,CTSZ,ZNF219,HDGFRP2,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,GPC3,MGAT4A,FAM20B,CST3,BAX,RAG1,MED22,PARP9,ACBD5,PLSCR1,TACC1,PIK3R1,DUSP23,MRS2,NUB1,UBE2A,PGBD1,AK4,RAB3IP,C4orf27,LDLRAP1,PROM1,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,FAM3C,PLA2G15,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,SRSF9,ACOT7,PHC1,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,NENF,ITPR2,MGAT5B,SLC9A3R2,FANCI,TFAP2E,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,ARL1,PSMC2,SLC44A1,MITF,PASK,TMEM143,ABCA2,SCARA3,SMAGP,PLK1,THRB,KCNIP3,PTPN18,STAU2,CBX6,NFE2L1,CCBL2,ARFRP1,EAF2,SESN1,KDM4D,TRIM9,HS6ST1,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,KPNA2,TC2N,RRAGD,RUNX2,LMTK3,PARP12,LGALS3,HJURP,DNAJB2,FXYD3,PSMD7,SORBS3,ADCK5,RAB6A,HES2,RSAD1,B4GALNT1,TIMP1,RINL,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,USP31,RGMB,MGAT4B,ZNF320,EMC2,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,PRX,NMT2,CDK5R1,C18orf8,FOXD2,FA2H,COL13A1,PHLPP2,P4HA3,NLRC5,ZDHHC7,FAM213A,PLD1,AKIP1,CDAN1,CCNB2,USP43,RAD21,HOXB7,CTDSPL,TP53,P2RX7,RHPN2,BAHD1,PCBP1,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,KMT5C,WDR44,TACC2,BCL6,PLK4,ZDHHC23,VAT1,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,ACO1,DAG1,CFAP36,ATP13A2,PTGS2,TAPBP,ZNF628,IDE,RBL1,STK38,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ST3GAL1,FAM134B,ARFGEF3,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CPEB4,TAB3,CTSB,SCD5,MCTP2,CDCA8,ERCC6L,ERI2,GTF3A,HMGN3,AIP,LBR,VPS26A,PARM1,H1FX,DNAJB9,FZD6,M6PR,ZDHHC21,FOXP2,CDK16,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,HMGCL,SYK,ATP2B1,GCNT1,WBP5,DUSP1,NFE2L3,P2RX4,HES1,RHOA,HMGN5,GUSB,PLAUR,PRICKLE1,DPP9,STMN3,MAML2,GGH,COL7A1,TXNDC11,RNPEP,USP6,BCL10,DDX23,CNOT2,DDAH1,SCG2,NEIL3,NIPSNAP3A,FGF18,E2F1,SH3BGRL2,PTGES,HIPK3,ZBTB33,PKIA,GOLGB1,LAMP1,SLC35D2,TXN,PNISR,SSH1,HSPG2,TSC22D3,CUL1,PSME1,CAMK1D,SEPT4,VASH1,PJA2,OAT,PICK1,SLC9A7,PAK6,HELZ2,CYP1A1,ZNF823,STIM1,OSBPL3,PALD1,FOSB,POLL,KCNS3,IRF2,SNX16,TACSTD2,HYLS1,MARCH2,ZBTB18,SGCE,SPATA18,CDYL,BNIP3L,SLC35C1,KIF13A,LDB2,POR,RAB2B,PRIM1,PPP2R4,PRDM5,BMP1,NFKBIZ,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,SCOC,TBC1D1,THEMIS2,TMEM55B,PRKAA1,AKAP17A,TXNDC9,HERC6,APBA1,PDXDC1,PSIP1,SH3RF2,MESDC2,C9orf69,CALR,DOPEY2,ZNRF2,BHLHE41,VASN,MSH2,TPST1,PRKG1,DLX4,ZNF117,SYTL3,GPR161,TRAK2,PIGC,GID8,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,CALM1,WHSC1,NPC2,ATP8B3,ANTXR1,JADE2,NFIB,AP1AR,TJP3,FAM64A,FAAH,WDR19,ZDHHC20,AGBL5,PIAS2,APPL2,ARAP1,SFMBT1,CABIN1,KLK7,SAMD8,ZBTB34,PLIN3,PER3,IFIH1,EHD1,FOXO6,SPRED1,TCF25,DLGAP5,GPR107,THRA,CERCAM,NDRG1,CCDC110,ATP2C2,FTH1,BCL2L1,FLT3,CYP39A1,ZFYVE9,EPM2A,APOBEC3B,CD46,NOV,CCNA2,ACAP2,RALB,RNASEH2A,PDE4D,OSBPL7,TSPAN1,SULT2B1,FLOT2,NAGA,MED30,SEMA3B,ATG4D,MSANTD4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,CLSTN1,KIF1C,RAD17,PYGO1,PKMYT1,CBL,B3GALNT2,ITPR3,TRIQK,ATP10D,CEP162,ZMPSTE24,DDOST,ACAD10,NGFRAP1,TRIOBP,SLC27A3,CBX7,MAMDC2,IGFBP6,DEPDC1,CENPI,CBLL1,PBX3,PLD2,FBXO6,SPDL1,EFNB1,COX7A2,HLA-A,WWP2,SCML1,SLC25A36,E2F7,GOLGA2P5,RNF128,GNB5,FUT8,DRAM1,CD9,CITED2,TTPA,MSH6,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,PAPD7,ZC3H11A,TCFL5,ZKSCAN2,DIAPH2,UBAC1,YES1,FOS,ARSK,CPTP,CRTC2,TIMP3,ACADSB,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,FZD5,ESPL1,DEF6,RGMA,CCNC,FAF2,UGT8,CRYM,UBE2Q1,VARS2,MPP5,COMMD5,MAP1LC3B,ERP29,SLC8B1,ECI1,TRIM68,ZFYVE16,RAB15,HSF2,CASC4,METTL7A,CDKL5,SIVA1,ASH2L,CTTN,MYRIP,BTBD3,STK35,SP5,LAMP3,CERS2,CYP1B1,CXXC5,CENPA,ASXL1,LAP3,ITCH,ACBD3,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,TDRD7,SH3GLB2,ZNF165,SP6,GLA,CHPT1,NRGN,CAPN1,NR2C2,PCSK5,ZNF395,SERPINE2,PPP1R12A,ETV5,ASB9,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,CES2,FAM20C,OCRL,COL6A1,SUCO,PRKCI,SRP54,BRAT1,HLA-C,ZRANB1,GAD1,ETV7,CCDC88A,MDFI,SNX7,ELK3,KIAA1109,PRRC1,NUBP1,PDIK1L,C3orf58,STEAP1,RANBP9,SOX13,INSR,UAP1,TMEM30A,SH3BP4,SPAG7,RAB31,DCUN1D1,CTSA,DONSON,TOB1,APOL2,COL16A1,RARG,SNX30,DRD1,LMO7,CCNE2,SORBS1,PAX6,FAM214B,HDAC11,SOD2,PDIA5,COL18A1,OSR2,SAYSD1,PHLDA1,EXT2,MXD1,SAP130,ZNF687,CYP4F11,COX14,KIF14,REEP1,ZBTB49,ECE1,NFKB2,ETHE1,UPF3A,EBAG9,CHP1,SEPHS1,SOAT1,RFK,C3orf52,MRPS35,TMTC2,CD40,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,HSF4,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,PTBP3,MAD2L1BP,ABCA1,KDELC2,GLIS3,CIT,SHPRH,SH3D19,ARHGEF7,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,A4GALT,MYCL,TOX2,RRBP1,ZDHHC13,ARVCF,H2AFY,KANK2,RPGR,SLC35A1,RBMS2,MYO5A,B3GALT6,DCAF6,CFAP46,SYBU,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,LEMD2,CTSL,CASP7,SWAP70,RND3,TRIM69,CTSV,RAP2C,CSGALNACT1,UACA,ARRB1,MCUR1,ZMIZ1,PLOD3,AHR,ABCG1,DOC2A,ACACB,KLK10,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,SMARCAL1,MMADHC,FBXO2,XIAP,DHX8,LGI3,MORF4L2,SYTL4,BARD1,PHF1,EPDR1,TP73,CALM2,DAPK2,WEE1,ZYX,PQLC2,PSMD1,RGS12,AP1M2,CABP1,CYP2S1,KLF3,RDH14,FUT1,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,VPS11,SMARCA2,SPEF2,TNIP1,SERTAD4,SH3BGRL,SPRTN,RNF11,MTRF1L,LOXL2,ICMT,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,LIMK1,SERPINB6,MRPS28,ARF6,E2F8,PDPR,HOXC13,ALDH6A1,NFKBIE,FAM169A,NUAK1,CYP2J2,SOX9,SLC36A4,LMNA,ELF3,RAVER2,GNS,DNPEP,WDFY1,PRICKLE4,ZIC5,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,NAGPA,UFD1L,KIF20A,SALL4,STAT4,MYBL2,CALCRL,SRSF5,ILK,MEST,TP53INP2,SPTLC2,RHOB,DCP2,CYB5A,DHX32,STK17A,NCOA3,SCARB2,NAAA,MTFMT,TIMM8A,HTT,SETD3,TEX30,ITPR1,AURKA,DYSF,MDH1,ALG2,B4GAT1,ARPC2,ZNF502,RPS6KA3,CSRP2,XDH,EGLN1,MTM1,CCDC109B,GRHL2,TUBB4B,GALNT12,ACTR8,ETNK1,RGS20,WDTC1,TESK2,PKP2,NUF2,PRKACA,APC2,KTN1,ZNF385B,CDS1,CCND1,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,RNF169,SSH3,NRBF2,FZD4,PLEKHO1,SYNE2,NUSAP1,CDCA2,PXYLP1,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,GEN1,ARNT,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,PDIA3,GMCL1,PKN1,TMA16,NUCB2,ETS1,GSTP1,HOXB2,TIPRL,NEO1,PDIA4,DTX3L,CAPN2,ANK1,ADD3,IRAK1,CTSC,ARSG,ANKS1B,ALG13,FDXR,PLEKHF1,ECI2,ADAM15,TMBIM6,WWP1,ZNF230,MAPK11,AK3,ITM2C,TPCN1,S100A6,TMX1,CRTAP,MOB4,AMOTL2,POU6F1,NUDT8,FMN1,BCL9,RAPGEF2,ELOVL3,EIF5A2,GRIN1,DBR1,PLEKHA7,NEURL1B,FAM109A,CRISPLD2,TXK,GALNT3,PITX2,BTG1,KIAA0141,NR1D2,ATXN7L3,ZFP30,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,FOXA1,UNKL,UNC93B1,AGRN,CUL4B,EPHA4,SUDS3,MCCC1,NDC80,CDIPT,HDAC6,PDGFB,NUP62CL,SDC1,PIGL,PCNA,LMAN2L,DDHD2,ELF5,DUSP10,PXMP4,TRAM1,MYBL1,DDX59,S100A13,ZNF462,PCGF5,ING1,HN1L,CITED4,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,RHEB,OPTN,DPYSL3,IRX3,PLCH1,MFAP3L,TBC1D17,MSL1,CDCA4,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,POMT1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,UBASH3B,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DHRS3,PGAP1,SSX2IP,RB1,DAZAP1,IGF1R,GATA2,CMTR2,PAK2,EXOC8,MDFIC,TMEM8A,ALDH3A2,PSMA5,C9orf9,CYP26B1,CHSY3,MRPS33,PCBP3,SPATA13,KBTBD8,TCF7,IFIT3,ZDHHC3,G2E3,SMN1,MAPKAPK2,MOSPD3,EPN3,COQ10A,H1F0,MFSD2A,ATP1B3,TMEM120A,CTBP1,IFI6,NIPA1,RNF146,NF2,UGP2,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,ERBB2,CCNL1,FAM198B,LPIN3,CYP26A1,SDF4,PER2,CDK14,RAD23A,ATP6V0B,SRPX,LHX6,N4BP3,MINPP1,EGLN3,FAR1,GM2A,DVL2,CTH,CPD,SIRT1,TMTC1,MBP,EVA1A,TCEB2,FIGNL1,COQ10B,S100A4,CDC20,MYPOP,DNAJC10,ATP1A1,PSMD3,ZBTB6,RPL22,AIFM3,LTA4H,CNEP1R1,ZNF701,POMGNT2,NDST3,COPG1,ZC3HC1,MAN2B2,GSDMD,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,CD63,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,GBX2,MAGEE1,SLC35B4,BUB1,ABCD1,KLF9,HEXIM2,CAMK2G,TLE6,MLEC,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,CARD19,TRIM35,FXR2,AKAP3,FNDC3A,BCAR1,MAPK8IP1,PRDX4,FUCA1,TMEM50B,SERPINA1,ZNF214,CDCA7L,NMI,PGRMC1,PPP2R3C,PKD2,SPCS3,ACADM,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,FAM129B,ATP8A1,TAP1,GATA3,PLXNA1,CCNB1,PLA2G16,RIC1,CENPN,NCS1,CHST2,SESN3,CTGF,ZFP36,RGS3,STEAP2,TFG,PACSIN1,LAMP2,LOC81691,SNTB2,PBK,CASP9,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SAV1,SLC25A5,ULK2,SGPP1,AHRR,SFXN1,KDSR,HLF,SLC25A4,RBM47,AREG,GNPTAB,TBX1,FAM110C,SARAF,DHTKD1,TMEM8B,RTN3,DLAT,KLF2,MRPL44,INPPL1,HLA-E,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,NDUFA4,SLC1A3,NOTCH2,KIAA1161,BMP2K,MECOM,SNX18,NECAB3,BDH1,SORL1,PIKFYVE,CTSD,EEF1D,TMED2,FAM69A,EPB41L5,FADS2,DDB2,PMPCB,QSOX1,B3GNT7,MMD,ZNF84,B9D2,AMER1,PIP4K2C,VEZT,PKM,KDM3A,GLT8D2,STX3,FAS,DGKH,SERTAD2,PRKAG2,DCK,NAB2,TCEAL4,FGD6,NR4A2,MAP3K5,NRBP1,IRF1,PLA2G4A,ELK4,SLC2A4,ARMCX3,CEP70,NLRX1,S100A11,TRIP10,RPS6KA1,CAST,SUZ12,IRX4,EGR3,SNN,AIFM2,NUDT12,MNS1,GNB2,SLC25A35,CYHR1,APLP2,ZNF75D,CDKN1B,TNPO2,DAB2IP,LGMN,NR2C1,TMBIM1,GPX4,MYO5B,SEC23A,CDKN2AIP,TMEM43,DMTN,LYRM1,TEP1,COX11,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,NIN,PRDM11,ZNF641,FYN,JAK1,PPP2R5A,CFAP45,STK26,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,HS3ST3B1,B4GALT3,NR3C2,ATMIN,MRPS9,NUDT6,ANKRD13D,JRKL,ATP9A,ARL4C,CCNJL,APOBEC3H,SPR,SLC35G2,TEAD3,SIX4,AKIRIN1,FAM111A,OXCT1,PHF7,PTEN,PPP1R10,MGAT1,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,CNOT6L,MAP3K7,GFI1,CNPY3,SPRY2,NCOA2,SMC4,PCCB,SHMT1,CASK,DENND1B,TEF,PARP4,VAMP3,FURIN,C1GALT1C1,GPLD1,NUCB1,RGS9,CTNS,PRDX3,SLC25A40,CSTF2,GPER1,NCAPG2,ARSB,SLC25A38,CPEB2,OCLN,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,CPT2,CAMKK1,UBE2Z,KIF2C,TAF6L,DNER,TSEN34,SH3KBP1,ABCD4,CHPF,MAGOHB,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,ANKRD12,KIF22,SUN3,RAB20,RP2,NFU1,ARNT2,TECR,PTPRE,RASGRP1,ATL1,TDP1,SOD1,TRIM8,ASCL5,SYNE3,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,TCN2,SEC14L2,NEIL1,ZNF114,FASTKD1,TRIM45,IARS2,APBA2,RAP1GAP,PSMC1,PPP2R5D,STARD3NL,GRN,FAM213B,PIFO,PEX6,ELOVL7,ATP6V1E2,SAMD9,PHLPP1,ZNF432,EBF4,ZNF692,KNTC1,RFX5,ACAD8,NCEH1,LRIF1,HP1BP3,KDELR1,OXR1,GYLTL1B,HMG20B,FBXO8,EGFR,GLCE,GNAS,FECH,NUDT16,TSC1,ONECUT1,PLPP3,UTP14C,PAPD5,NFKBIA,CDCA5,ALPK3,KLF7,SLC25A24,SPC25,IL15,SLC2A8,PSME2,MORC4,TDRKH,MICALL2,PATL2,LRRC45,SLC25A48,SS18,SETDB2,ZDHHC12,SMO,GOT1,TWIST1,STEAP3,RPN2,F2R,PDIA6,LOXL1,SCYL3,HSPA2,ZNF525,TAF5,BAG4,KREMEN2,OSTM1,AP5M1,ERBB2IP,DUSP4,SNAPC2,BFSP1,BHLHB9,PEX2,OVOL1,CANT1,CYP2U1,AKNA,SGOL1,REEP4,CBX4,ANXA3,CDS2,SORT1,JKAMP,MIER3,AES,TRMT2B,POMGNT1,ZNF212,IRF2BPL,SNX13,MDM1,ADORA1,GALNS,KIAA0319,CKS1B,TRIM3,BRD7,HSPA13,MXD3,SUN2,SYPL1,RAB3B,CENPC,ASPM,NR4A1,MBNL3,OGDHL,POLD3,MPV17L2,SPAG1,HLA-B,MARC1,C2orf70,DHRS2,PRCP,HNRNPH2,TADA2B,UBE2D2,OTUB2,GLB1,HOXB13,GEM,ATP6V1C1,SOX8,ZNF596,SNPH |
| 2.013e-13 | -29.23 | DOUGLAS_BMI1_TARGETS_UP | MSigDB lists | DOUGLAS_BMI1_TARGETS_UP | 536 | 142 | 17758 | 2588 |
TMEM184B,AASS,CRYM,ISOC2,TP53I11,PJA2,DNER,SDC1,RAB15,ZYX,IL6ST,ALDH1A3,ATP13A3,ABCA2,RP2,TIPARP,IL10RB,STK35,ACBD3,PRKAR2B,LOXL2,ICMT,PTGFRN,CLCN2,TYSND1,TRAM2,MPRIP,GPRC5B,ZNF367,RAB11FIP1,KLF11,ITPKA,INPPL1,FRMD4A,CNTNAP2,SLC1A3,TSPAN7,WDFY1,UBE2Q2,COL6A1,TMEM51,FXYD5,NPTN,FAM84B,HPS3,USP31,KIF20A,DCHS1,ANKRD29,SLCO4A1,CACHD1,SLC6A6,TMEM54,COL13A1,MFSD2A,PRPS2,ZDHHC20,FAM83D,PIAS2,NXPH4,RHOBTB2,PITPNA,GDF11,COL16A1,RUSC1,KCNAB3,UGP2,IQGAP1,CERCAM,IL27RA,KCTD12,EMP2,ZFYVE9,CDK14,PDGFA,SS18,KCTD15,RALB,XYLT2,GLB1L2,DAB2IP,STEAP3,NOTCH3,F2R,LOXL1,PPIF,BAG4,TIMP2,COL6A2,GLO1,MRPS35,ATP1B1,C15orf39,CMTM7,IRS2,ACYP1,KIAA1804,INPP4B,VSIG10,REEP4,KDELC2,TAOK2,FARP1,RBM24,SCD5,SLC41A1,OSGIN2,AES,GTF3A,TRIB2,SPR,EFNB1,XPR1,NEO1,IGSF9,ADRBK1,MGAT1,CTSC,BMP7,PRC1,TRIM3,CITED2,C12orf75,IGDCC4,PDGFC,PAPD7,NR4A1,MPP1,TCFL5,BCL9,YES1,POLD3,KIF11,TMEM50B,TIMP3,ZMYND19,RYK,HMGA1,FZD5,PLOD3,HIPK3,PKIA |
| 2.040e-13 | -29.22 | protein phosphorylation | biological process | GO:0006468 | 942 | 223 | 16441 | 2455 |
TNK1,ACVR1,TRIM24,CAMKK1,EPHA4,RET,CUL1,NRG2,PSME1,IL18,CAMK1D,CCNB1,PDGFB,SPTB,PICK1,GRM5,CALM2,PAK6,DAPK2,WEE1,PSMD1,RPS6KA2,TGFBR3,SHC3,CDKL5,PSMC2,IL31RA,PASK,PIK3CA,DUSP10,PIK3CD,STK35,RASGRP1,PLK1,NEK4,MARK1,ACVR1C,PBK,ROR1,AURKB,PRKRA,CDK1,STK17B,ADRBK2,ULK2,FASTKD1,PLK2,SH2D3C,LIMK1,MYLK,NOD2,MAP3K11,CAB39,MAPK13,RNASEL,ITPKA,PSMC1,GAB1,PPP2R5D,PRKAA2,CDK17,LMTK3,NUAK1,RASA2,SOX9,PRKAA1,PSMD7,CALM3,ADCK5,TEC,TNFRSF19,MERTK,DUSP5,BMP2K,BMP2,IGF1R,FAM20C,PAK2,PPP4R1,NEK2,DAPK1,ADCK2,MAP3K9,PRKCI,PRKG1,MDFIC,NPTN,ALPK1,PIM1,NCAM1,MAPK7,MAST4,PHKG2,PSMA5,MDFI,MMD,TESK1,MAPKAPK3,STAT4,CALM1,STRADB,EIF2AK1,EPHA1,PDK3,ELK1,ILK,PDIK1L,PSMA4,EGFR,RASA1,CDK5R1,STK17A,MAPKAPK2,PRKAG2,INSR,CSNK1G1,AURKA,ALPK3,STK39,CDK18,MAP3K5,JAK3,NRBP1,CTBP1,RPS6KA3,DMPK,SPRED1,IL15,RPS6KA1,PSME2,ERBB2,P2RX7,TESK2,RASGRP3,MAPK4,GRK6,PRKACA,FLT3,DDR1,CDK14,PDGFA,CCND1,DOK4,PLK4,DAB2IP,EPHB4,PHKA2,RASGEF1A,F2R,SCYL3,FRS3,MAP3K3,RIPK2,AKT1,PTGER4,PRKCQ,PKMYT1,XRCC6BP1,DUSP4,MAP3K6,EPHA10,IRS2,FYN,JAK1,CDK19,STK26,PSMD3,AXL,STK38,PTK7,KIAA1804,NRG1,SPTBN5,MLKL,ST3GAL1,MAPK12,PINK1,DYRK3,TAOK2,TAB3,CIT,CCM2,PSMD10,TGFBR1,PKN1,TRIB2,FGF19,ADRBK1,IRAK1,CDK16,SGK3,SGK1,BUB1,MAPK11,ERCC2,ERBB3,MAP3K7,IQGAP3,SYK,CAMK2G,RASGRF1,CASK,PSMB4,RAPGEF2,PIK3R1,GRIN1,RUNX3,YES1,PIM3,FOS,MAPK8IP1,PRDX4,TXK,FGFR2,SCG2,ACVRL1,FGF18,RYK,GRIN2D,ITGAV,LRRK1,HIPK3,MELK |
| 2.074e-13 | -29.20 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP | 198 | 70 | 17758 | 2588 |
SUN1,CASP3,MTM1,TXN,DLGAP5,NDRG1,SUZ12,KIF2C,CDKN2C,WEE1,CCNA2,UBE2T,SIVA1,CAPG,PLK4,KIF22,SNX10,CKS2,CENPA,S100A4,CDC20,NUSAP1,AURKB,ANLN,CCNF,DOCK5,CDC25C,CDK1,PRIM1,GABARAPL1,RBL1,KPNA2,E2F8,CD99,LGALS3,SERPINB9,CDCA8,CDCA3,KIF23,CKAP5,TOP2A,CA2,NEK2,PRC1,CKS1B,BUB1,STT3B,AK3,TAGLN2,IQGAP3,PSMA5,SYPL1,KIF20A,IFITM3,ASPM,NR4A1,LITAF,EMP3,GGH,PDK3,KIF11,PRDX4,GALNT3,TMEM50B,H1F0,DCK,DBI,AURKA,GEM,CCNB2 |
| 2.182e-13 | -29.15 | positive regulation of metabolic process | biological process | GO:0009893 | 3495 | 661 | 16441 | 2455 |
ACACB,TRIM24,TRIM5,PNPLA2,DNAJC3,HEXB,RET,XIAP,NRG2,IL18,MORF4L2,SNX9,BARD1,CARD10,PHF1,GRM5,TP73,NPM2,CALM2,ARHGAP42,PSMD1,RGS12,DNM2,PIK3CD,TIAM1,TIPARP,NEK4,VPS11,SMARCA2,TNIP1,SPRTN,TFAP2C,PRKAR2B,F12,RNF19B,ARF4,ABR,PIAS3,PLCG1,MID1IP1,ANKRD6,NOD2,MAP3K11,AGFG2,HDAC1,RNASEL,HSPB1,STARD13,E2F8,GAB1,HOXC13,GGA1,ITGA6,SOX9,LMNA,ELF3,TFAP4,FAM13B,RANBP1,NEK2,MAP3K9,MYDGF,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,MAPKAPK3,SALL4,STAT4,PYM1,FHL2,MYBL2,CALCRL,ELK1,ILK,TP53INP2,PSMA4,PLIN5,NCOA3,FNTA,ETS2,SEMA4D,SETD3,ITPR1,AURKA,STK39,GDF11,RPS6KA3,TMEM173,XDH,DOCK9,ARHGAP11A,GRHL2,RGS20,MGST2,PRKACA,APC2,CCND1,ST5,CDH1,SP100,SH3BP1,DACT1,TAX1BP3,RASGEF1A,MYT1,ETV4,PSRC1,RIPK2,FZD4,PFKFB2,CDCA2,PXYLP1,GTF2A2,EBF2,NFIX,IRS2,CORO1C,WFS1,SIPA1L1,WWTR1,PLEKHG1,RGS14,ARNT,MAPK12,FARP1,TAOK2,NKX3-1,TNRC6C,CKAP2,TRAF2,SDC4,FLOT1,PKN1,ETS1,GSTP1,ARHGEF40,NFAT5,ICAM1,PDCD10,ITGB8,IRAK1,CTSC,KNDC1,GPC3,MCF2L,CST3,BAX,PLEKHF1,MAPK11,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,RAB3IP,ABLIM2,TXK,PITX2,LDLRAP1,ATXN7L3,NR1D2,ACVRL1,NR4A3,ARFGAP3,CENPE,HMGA1,OSR1,CD81,USF2,SHOX2,FOXA1,AGRN,EPAS1,CNOT8,CUL4B,EPHA4,ARFGEF1,DNAJB11,F11R,NENF,ITPR2,HDAC6,PDGFB,SPTB,FANCI,TFAP2E,PCNA,RPS6KA2,CTNNB1,RABEP2,NPNT,SHC3,IL6ST,ARL1,PSMC2,MITF,ELF5,PASK,TNFRSF18,RGS5,MYBL1,ZNF462,PLK1,THRB,PCGF5,CITED4,NFE2L1,EZR,EAF2,PRKRA,CDK1,VCP,KDM4D,PLEKHG6,TBC1D17,KLF12,PRKCDBP,MAFF,PRKAA2,RUNX2,DNAJB2,RASA2,PSMD7,SORBS3,RACGAP1,DOCK11,FBLN1,BMP2,RB1,DAZAP1,IGF1R,RINL,GATA2,PAK2,TBCD,MDFIC,PIM1,WNT3A,PLCB2,PSMA5,RGMB,SPATA13,STRADB,SCRIB,BCL2L13,CDK5R1,RASGRP2,MAPKAPK2,CSF1,NLRC5,ATP1B3,CTBP1,RAD21,AVPI1,UPF3B,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,CCNL1,LPIN3,STIL,EMP2,BCAP31,IER3,PDGFA,LMO4,PLCG2,BCL6,CDH3,NOTCH3,EGLN3,GM2A,DVL2,CTH,SIRT1,CLCN3,TIMP2,TCEB2,AKT1,CDC20,SERTAD3,PTGS2,DNAJC10,RBL1,MMP17,PSMD3,EFNA5,IRF7,ARHGAP4,CNEP1R1,ARFGEF3,PINK1,CD63,TAB3,DAP,GNAL,PSMD10,GDF15,HMGN3,PARM1,PPP2R3A,GBX2,GTF2F2,TFAP2A,TRIM21,SYK,CAMK2G,P2RX4,NFE2L3,HES1,RHOA,HMGN5,PSMB4,NR3C1,PLAUR,PPARA,PRICKLE1,MAML2,BCL10,DDAH1,BANK1,NMI,FGF18,E2F1,PPP2R3C,PKD2,NDFIP1,TBC1D4,UBE2C,ARHGEF9,ARHGEF4,ACVR1,TXN,LGR4,GATA3,CUL1,PSME1,CAMK1D,CCNB1,SEPT4,ELMOD2,RIC1,PICK1,PAK6,HELZ2,CTGF,ZFP36,RGS3,IL31RA,FOSB,PIK3CA,SERINC2,IRF2,ACVR1C,CASP9,AURKB,SAV1,LDB2,POR,ARHGEF26,AHRR,AREG,PLK2,TBX1,SH2D3C,NKD1,PPP2R4,F2RL1,TRAF5,FGD1,DDX58,KLF2,SCOC,CDKN1C,TBC1D1,PRKAA1,PSIP1,MECOM,CALR,ITGA3,RALGPS2,CYR61,SNX18,DAPK1,MSH2,SORL1,GPR161,RIMS2,SOCS5,MMD,MFI2,TBC1D8B,CALM1,PIP4K2C,WHSC1,KCTD20,EPHA1,CYFIP2,KDM3A,NFIB,RASA1,FAS,MMP15,PRKAG2,SERTAD2,PELI2,ARAP1,PIAS2,FGD6,NR4A2,EFNA1,MAP3K5,IRF1,PLEKHG3,SPRED1,DLGAP5,ARMCX3,THRA,RPS6KA1,IQGAP1,RALBP1,FLT3,EPM2A,EPS8L2,CD46,ACAP2,CCNA2,RALB,CDKN1B,DAB2IP,OSBPL7,MED30,TBC1D10B,DOCK4,FOXJ2,PRKCQ,SLC11A2,PYGO1,ATP1B1,ITPR3,FZD7,FYN,PPP2R5A,JAK1,STK26,NGFRAP1,KIAA1804,STAT1,SLC27A1,NRG1,KLF5,ATMIN,PRKAR1A,DENND5B,ARHGEF3,PCOLCE,DEPDC1,PBX3,FGF19,TEAD3,SIX4,WWP2,E2F7,RNF128,PTEN,ERCC2,ERBB3,CITED2,MAP3K7,TRIM62,SPRY2,MSH6,NCOA2,FARP2,PDGFC,RASGRF1,CASK,ARHGEF28,ARAP2,DENND1B,TEF,FURIN,VAMP3,YES1,GRTP1,FOS,GPLD1,CRTC2,RGS9,FGFR2,RCBTB2,PRDX3,RIN3,RYK,GRIN2D,LRRK1,GPER1,FZD5,ESPL1,USP16,RGMA,JARID2,CCNC,CASP3,CAMKK1,ERP29,DENND2D,EPCAM,ARHGEF10L,SIPA1L2,HSF2,GRHL1,CDKL5,ARHGEF37,DLG1,ASH2L,RP2,ARNT2,SLC39A10,RASGRP1,SOD1,TRIM8,ASXL1,ITCH,ARHGDIB,EDNRA,SEC14L2,MDK,ARHGEF19,GPRC5B,MADD,CAB39,RAP1GAP,PSMC1,NR2C2,PIFO,ARAP3,PPP1R12A,BVES,ETV5,ASB9,CALM3,TEC,DUSP5,NOXA1,OCRL,EBF4,SUCO,PRKCI,FNIP1,BRAT1,NPTN,ALS2CL,CCDC88A,MDFI,ELK3,FBXO8,PDE5A,EGFR,GNAS,BCAR3,ONECUT1,TSC1,NUDT16,INSR,PLPP3,NFKBIA,SH3BP4,DCUN1D1,CTSA,JAK3,TOB1,RARG,PROM2,DRD1,KLF7,SORBS1,PAX6,IL15,PSME2,OSR2,ARHGEF16,SS18,KIF14,SMO,ZBTB49,TWIST1,ECE1,EPB41L4B,NFKB2,F2R,HSPA2,UPF3A,FRS3,CHP1,MAP3K3,SOAT1,BAG4,RFK,ERBB2IP,CD40,DOCK5,MAP3K6,ARHGAP35,JADE1,HSF4,STAT6,TLE1,SPTBN5,AKNA,ABCA1,GLIS3,GCLM,ANXA3,ARHGEF11,ARHGEF7,SH3D19,SERPINB9,TGFBR1,TRIB2,SBF1,SYDE2,IRF2BPL,TOP2A,SNX13,CARD8,ADRBK1,ADORA1,LLGL2,BMP7,TOX2,ACTA2,BRD7,H2AFY,IQGAP3,RPGR,DCAF6,ADAM17,WNT10B,NR4A1,GCLC,RGCC,RUNX3,MPV17L2,ARHGAP24,CASP7,RAP2C,TADA2B,ARRB1,ZMIZ1,SOX8,AHR,RAB3IL1,ABCG1,NGEF |
| 2.193e-13 | -29.15 | MODULE_38 | MSigDB lists | MODULE_38 | 447 | 124 | 17758 | 2588 |
MYL9,LTBP1,HSPG2,EPAS1,S100A11,TRIP10,DGKA,GATA3,ERBB2,NRG2,SDC1,EMP2,PDGFB,ARHGEF16,CHPF,IER3,CCND1,ZYX,ST5,TGFBR3,SRPX,CDH1,SH3BP1,TACC2,FOSB,DNM2,CLDN4,TACSTD2,ECE1,NOTCH3,LGMN,SMYD5,HSPA2,SMAGP,VPS11,COL6A2,TIMP2,PTPRU,PFKFB2,S100A4,PTPN9,CDA,TFAP2C,PKMYT1,DUSP4,PGF,TRAM2,AGPAT2,WFS1,MYLK,BMP1,MAOA,TLE1,PLXND1,PDXK,ARHGAP4,MAFF,ABCA1,GRN,PRSS8,INPPL1,PCOLCE,CDKN1C,DNAJB2,DCAF7,BLVRB,SERPINB9,ETV5,GNE,ARL4C,GDF15,DHRS3,FBLN1,EFNB1,DUSP5,TEAD3,M6PR,TMEM63A,SPP1,ITGA3,CYR61,CTSC,LLGL2,LYPD3,GATA2,GPC3,KCNN4,FDXR,COL6A1,DAPK1,TFAP2A,IGFBP2,ERBB3,PIM1,CITED2,CLIP2,PLCB2,IGSF3,QSOX1,HES1,PCDH1,MAPKAPK3,MPP1,FURIN,EMP3,TCF7,MEST,RHOB,CDK5R1,EGFR,IL1R1,MMP15,FUCA1,TIMP3,ETS2,PVRL2,SEMA4D,RAB31,DTX4,SLC4A3,EFNA1,LTBP2,JAK3,OCLN |
| 2.320e-13 | -29.09 | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR | MSigDB lists | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR | 122 | 51 | 17758 | 2588 |
DLGAP5,SPC25,DEPDC1,CKAP2,PTTG1,CDCA8,KIF23,RACGAP1,NUF2,FAM198B,CHAC2,CCNB1,FBLN1,CENPN,LBR,TOP2A,MAGOHB,PCNA,CCNA2,UBE2T,RANBP1,PRC1,NEK2,KIF22,BUB1,USP1,KNTC1,SULF2,SEMA3B,HMMR,TDP1,CENPA,KIF20A,ASPM,CDC20,MYBL2,NUSAP1,ANLN,BORA,KIF11,H2AFV,CDK1,FAM64A,WIPI1,NEIL3,E2F1,KPNA2,CCNB2,UBE2C,E2F8,MELK |
| 2.367e-13 | -29.07 | CAGGTG_V$E12_Q6 | MSigDB lists | CAGGTG_V$E12_Q6 | 2354 | 463 | 17758 | 2588 |
DOC2A,TSC22D3,PNPLA2,FBXO2,CACNA2D2,GATA3,NRG2,PSME1,CAMK1D,PLA2G16,SEPT4,LTBP3,PHF1,PICK1,SLC9A7,EPDR1,CALM2,CDKN2C,PAK6,TYMP,PHYHIP,CYP1A1,SESN3,AP1M2,RGS3,PAQR5,FOSB,SERINC2,SNX16,PIK3CD,ARMCX6,WBP4,TIAM1,TUBA4A,SMARCA2,FBXL16,DSTN,SERTAD4,TMEM151A,TFAP2C,TNS1,KIF13A,GALNT7,F12,PPP1R14C,SLC25A5,COL12A1,ABR,LCP1,SLC44A3,CAMK2N2,RBM47,ATP7B,SH2D3C,PPP2R4,MYLK,LRIG1,SERPINI1,SPRY4,UNC5B,ITPKA,ARF6,F2RL1,STARD13,RTN3,SCN5A,FRMD4A,CDKN1C,ITGA6,STRN4,APBA1,HPCAL4,PSIP1,FLII,SH3D21,RAC2,ITGA3,PIK3AP1,SLC16A6,MEGF8,BHLHE41,DAPK1,TNFRSF12A,USP1,CACNA1D,NCAM1,DLX4,MYLIP,KANK3,DGKG,RIMS2,TSPAN33,IGSF3,SOCS5,DNAI1,EPB41L5,CALM1,SHARPIN,PIP4K2C,EPHA1,SPTLC2,GNA11,PDE11A,MMP15,PRKAG2,ETS2,DGAT2,NR4A2,CDK18,EFNA1,MAP3K5,DRP2,HOOK1,RPS6KA3,IRF1,EGLN1,EHD1,DMPK,KIF3C,SPRED1,ARMCX3,GRHL2,TRIP10,THRA,CD82,IQGAP1,CAST,DDIT4L,WDTC1,IRX4,RNF182,IL13RA1,PRSS22,BCL2L1,PRKACA,DDR1,FLT3,GNB2,TMPRSS4,KTN1,ZNF385B,ZFYVE9,SLC25A35,CDS1,C11orf84,CYHR1,NOV,SCNN1A,RNF220,CDH1,ENPP5,RTKN2,ACSL4,OSBPL7,SNX10,ETV4,SULT2B1,TBC1D10B,SEMA3B,SSH3,PFKFB2,FZD4,FOXJ2,SYNE2,KIF1C,PRKCQ,ATP1B1,ITPR3,ALCAM,TRIM7,NFIX,OSBPL2,ALDH3B1,FYN,PDLIM3,AXL,CORO1C,NRG1,NR3C2,COBL,PRR15,MAPK12,IER5L,CTHRC1,NKX3-1,IGFBP6,BACE1,CCM2,SDC4,EPS8,ARL4C,PKN1,SEPP1,LGALS3BP,WWP2,CTNNBIP1,AKIRIN1,ANK1,PDCD10,ADD3,ITGB8,SLC27A6,RNF128,MGAT1,ARSG,TMEM62,FUT8,CD9,TAGLN2,ERBB3,AK3,RAG1,CNOT6L,CITED2,SPRY2,HCN3,PVRL4,ARAP2,LONRF3,TACC1,BCL9,DENND1B,TEF,ELOVL3,PIK3R1,GRIN1,C1GALT1C1,LRRC1,FOS,CTNS,ACADSB,DGCR2,PLOD2,CCDC6,SYT7,AMMECR1,NR4A3,CCDC69,SERPINB5,FBXO44,HMGA1,FZD5,OSR1,FOXA1,OCLN,DEF6,TLL2,RGMA,EXPH5,EMX1,LTBP1,SIGIRR,BCAM,EPAS1,PPM1J,CAMKK1,EPHX4,UBE2Q1,ITPR2,MGAT5B,SDC1,PDGFB,SPTB,EPCAM,NUP210,NPNT,P4HB,CASC4,LMAN2L,SLC44A1,ELF5,DLG1,ABCA2,NTN4,MYH14,BTBD3,NEB,STK35,CERS2,CYP1B1,OLFML2A,ZNF462,PCGF5,MARK1,CXXC5,TRIM8,CELSR2,ASXL1,CBX6,TNFAIP8L1,ESYT1,ROR1,ZBTB7B,PLEKHB1,DPYSL3,TNS4,MDK,PLEKHG6,GPRC5B,KCNK1,MADD,SH3GLB2,ARRDC1,CTNND1,SP6,LEMD1,EPB41L4A,NRGN,HS6ST3,RRAGD,BMF,SERPINE2,ZNF395,CHCHD7,UBASH3B,CALM3,SORBS3,FAM81A,DHRS3,DUSP5,SSX2IP,IGF1R,LRRN2,GATA2,KIF13B,PAK2,SELK,WNT3A,GAD1,PLCB2,MPHOSPH9,DPYSL5,ELK3,PCDH1,CORO2A,PARD3B,OXR1,MGAT4B,SPA17,GYLTL1B,VWA1,KBTBD8,TCF7,PDIK1L,UNC45B,RANBP9,ZDHHC3,NMT2,RASGRP2,EPN3,GNAS,COQ10A,FA2H,PVRL2,COL13A1,UTP14C,MFSD2A,ITGA7,NXPH4,DONSON,LTBP2,KIF12,SHROOM2,SEMA3A,RARG,CTBP1,NCKAP5,SORBS1,PAX6,HOXB7,XYLT1,DGKA,GMPR,COL18A1,TDRKH,BAHD1,PRR7,CYP26A1,CDK14,PDGFA,ATP6V0B,KCTD15,ARTN,TACC2,PLK4,BCL6,VAT1,CDH3,EPB41L4B,EGLN3,FRS3,SIRT1,GCA,KREMEN2,IGSF8,DUSP4,TMTC2,DOCK5,SOCS3,ATP13A2,DUOX1,PTPRJ,IDE,PAFAH1B3,RBL1,OVOL1,TLE1,SPTBN5,ANXA9,AIFM3,CMTM4,FBLIM1,COL9A3,MACC1,KLHL13,TAB3,GABRG2,SELL,CRABP2,TRIB2,LBR,NRP2,SIRPA,HDAC9,CCDC92,KIF5B,IRF2BPL,MDM1,ADRBK1,LLGL2,A4GALT,BMP7,TOX2,TFAP2A,UBE2J1,H2AFY,ARVCF,TSPAN13,CAMK2G,WNT10B,NR3C1,CRB3,NR4A1,PHLDB3,PPARA,PELI3,FNDC3A,TXNDC11,MAPK8IP1,CD83,ARHGAP24,DDAH1,SWAP70,SMTNL2,SCG2,SPINT2,E2F1,NETO2,UACA,SH3BGRL2,CEP41,AHR,PKIA |
| 2.541e-13 | -29.00 | multicellular organismal development | biological process | GO:0007275 | 4594 | 837 | 16441 | 2455 |
DOC2A,HECA,ADD1,AK7,RET,MCOLN3,HEXB,NRG2,IL18,KIF26A,GRM5,TP73,CDKN2C,NPM2,CALM2,WEE1,PSMD1,TGFBR3,PAQR5,ALDH1A3,KLF3,DNM2,CLDN4,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,TIPARP,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,GINS4,ABR,PGF,PLCG1,ENPP1,LIMK1,ATP7B,TRAF3IP1,MYLK,HDAC1,TMOD2,ITPKA,ARF6,LSM14B,GAB1,E2F8,HOXC13,SCN5A,TMTC3,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,FLII,RAC2,FRY,MEGF8,FLRT3,ZIC5,NEK2,USP1,MYDGF,NCAM1,DGKG,MYLIP,PAQR7,REC8,UFD1L,SALL4,SHARPIN,FHL2,CALCRL,KIF20B,NPHP3,ILK,DPYSL4,PSMA4,GNA11,RHOB,PTPRF,NCOA3,ETS2,HTT,TIMM8A,SEMA4D,ITPR1,DGAT2,CLMN,AURKA,B4GAT1,GDF11,CFAP20,DRP2,NDE1,ARPC2,TRPC3,RPS6KA3,CSRP2,XDH,ADAMTS16,EGLN1,PAPSS2,GRHL2,LFNG,INPP5D,WDTC1,PKP2,PRKACA,APC2,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,MYT1,SNX10,ETV4,SSH3,CAMSAP3,COL6A2,LGALS8,FZD4,SAT1,HTATIP2,EBF2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,CORO1C,WFS1,AXL,SIPA1L1,WWTR1,PNPLA6,RGS14,ARNT,MAPK12,TTC8,CTHRC1,NKX3-1,TNRC6C,FARP1,MAN1A2,DCAF7,SDC4,CCM2,BIK,FLOT1,GMCL1,CTSZ,PKN1,PLPPR4,ZNF219,ETS1,GSTP1,HOXB2,SRPX2,ICAM1,SGPL1,NEO1,CTNNBIP1,CAPN2,ZFX,ANK1,PDCD10,IGSF9,ITGB8,KNDC1,GPC3,CST3,BAX,ADAM15,TMBIM6,WWP1,RAG1,SGCB,ITM2C,S100A6,POU6F1,ADAMTS2,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,CRISPLD2,ABLIM2,TXK,CNTNAP1,PITX2,PROM1,ACVRL1,DBI,FAM3C,NR4A3,CENPE,ITGAV,FHL1,OSR1,USF2,SHOX2,FOXA1,PHC1,TLL2,MYL9,EPAS1,AGRN,CUL4B,EPHA4,SUDS3,ARFGEF1,PHOSPHO1,NDRG2,PDGFB,SDC1,SPTB,SLC9A3R2,PLS3,RPS6KA2,PCNA,CTNNB1,NPNT,SHC3,IL6ST,MITF,PSMC2,PAPSS1,ELF5,TMEM143,DUSP10,TNFRSF18,NTN4,NEB,THRB,MARK1,CELSR2,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CLCN2,CDK1,RHEB,PLEKHB1,DPYSL3,IRX3,HS6ST1,MAP2,HOXA9,POMT1,MAFF,MYL12B,RUNX2,USH1C,LGALS3,RASA2,PSMD7,RACGAP1,CNTNAP2,NCKAP1,FBLN1,DHRS3,PGAP1,IL18R1,ANO1,BMP2,TNS3,RB1,VASP,DAZAP1,TIMP1,IGF1R,GATA2,KIF13B,FRAS1,PAK2,PIM1,NTN1,WNT3A,ALDH3A2,PSMA5,CYP26B1,DPYSL5,PCDH1,RGMB,TCF7,SCRIB,EIF2AK1,UNC45B,G2E3,PRX,SMN1,CDK5R1,MAPKAPK2,MOSPD3,FA2H,COL13A1,PHLPP2,ITGA7,CSF1,PRPS2,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,STIL,EMP2,SDF4,PER2,PDGFA,TTC21B,TACC2,LMO4,LHX6,PLCG2,SRR,BCL6,PLK4,GYS1,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,TIMP2,MBP,AKT1,S100A4,CDC20,CCSAP,PTGER4,ACO1,MYL12A,DAG1,PTGS2,DUOX1,RTN4RL1,IDE,PTPRJ,PAFAH1B3,PTK7,PSMD3,EFNA5,RPL22,LTA4H,POMGNT2,CTDSP1,BIN1,COL9A3,DYRK3,CDH22,ADGRG1,CTSB,MCTP2,GABRG2,PSMD10,JAG2,CRABP2,FZD6,PPP2R3A,NRP2,GBX2,ZDHHC21,CD109,FOXP2,CDK16,TFAP2A,SGK1,HMGCL,SYK,CAMK2G,FAM134C,TLE6,GCNT1,DUSP1,HES1,RHOA,PSMB4,CRIP2,PPARA,STMN3,PRICKLE1,COL7A1,FNDC3A,BBS2,PRDX4,BCL10,CNOT2,FAT4,SCG2,TWSG1,FGF18,PGRMC1,E2F1,PKD2,PPP2R3C,GAA,ACVR1,HSPG2,SSH1,LGR4,VANGL1,TMEM41B,CUL1,GATA3,PSME1,CAMK1D,PLXNA1,CCNB1,VASH1,SEPT4,FAM101B,CHST2,NCS1,PICK1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,POLL,PIK3CA,TACSTD2,ZBTB18,PACSIN1,SGCE,CASP9,AURKB,LDB2,CCNF,SAV1,ZFAND5,ULK2,SFXN1,HLF,AREG,TBX1,PLK2,NKD1,LRIG1,BMP1,DHTKD1,SERPINI1,SPRY4,TANC2,UNC5B,F2RL1,LZTS1,FGD1,SEMA6B,KLF2,INPPL1,CDKN1C,SLC25A27,NOTCH2,SLC1A3,HERC6,APBA1,TNFRSF19,KIAA1161,MECOM,CALR,DOPEY2,ITGA3,CYR61,BHLHE41,PRKG1,MSH2,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,DLX4,TMED2,GPR161,RIMS2,IGSF3,DNAI1,SPATA20,EPB41L5,MMD,CALM1,AMER1,DCHS1,ANO6,WHSC1,VEZT,EPHA1,NFIB,STX3,RASA1,FAS,MMP15,MATN2,NAB2,FAM83D,PCDH19,NR4A2,EFNA1,HOOK1,EHD1,IRF1,SPRED1,FOXO6,TCF25,ST14,THRA,RPS6KA1,CAST,IQGAP1,NDRG1,IRX4,BCL2L1,EGR3,DDR1,FLT3,MNS1,EPM2A,NOV,APLP2,CCNA2,DOK4,CDKN1B,CNNM4,DAB2IP,EPHB4,PDE4D,SEMA3B,GPX4,DMTN,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CMTM7,EPHA10,FYN,JAK1,NGFRAP1,STAT1,RAB29,NRG1,KLF5,PRR15,CBX7,COBL,PRKAR1A,WASF3,PCOLCE,JRKL,HAPLN3,CENPI,PBX3,NES,SEPP1,SPR,FGF19,EFNB1,TEAD3,ADGRB2,SIX4,RND1,E2F7,OXCT1,MGAT1,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,ERCC2,MAP3K7,CITED2,TTPA,GFI1,SPRY2,OSGIN1,MSH6,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,TCFL5,DIAPH2,YES1,FOS,GPLD1,CDK5RAP1,RGS9,TIMP3,CTNS,DGCR2,FGFR2,PRDX3,TBX18,RYK,ERAP1,SERPINB5,GRIN2D,LRRK1,GPER1,FZD5,WDR62,ARSB,NCAPG2,SLC25A38,MELK,RGMA,JARID2,EXPH5,EMX1,CASP3,UGT8,UBE2Q1,PLAC1,MPP5,CACNB4,DNER,TMC1,EPCAM,LRRC6,GRHL1,CDKL5,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,ASH2L,CTTN,MYH14,ARNT2,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,SOD1,ASXL1,RNF165,ARHGDIB,EDNRA,CXXC4,MDK,GPRC5B,HPSE,TDRD7,TRIM45,NRGN,APBA2,PPP2R5D,PSMC1,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,DUSP5,SPP1,CA2,LRRN2,FAM20C,OCRL,COL6A1,EBF4,PRKCI,SUCO,FNIP1,NPTN,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,HMG20B,C3orf58,RANBP9,EGFR,FECH,GNAS,BCAR3,ONECUT1,TSC1,INSR,PLPP3,TMEM30A,UTP14C,ALPK3,PITPNA,DONSON,EGFL7,SHROOM2,JAK3,RARG,APOL2,DRD1,KLF7,PAX6,IL15,PSME2,HDAC11,COL18A1,MRAS,OSR2,MICALL2,PHLDA1,EXT2,MXD1,KCTD15,ARTN,SETDB2,FRYL,KIF14,SMO,DIXDC1,TWIST1,ECE1,NFKB2,LOXL1,FRS3,MAP3K3,PTPRU,OSTM1,IGSF8,GLO1,CD40,DUSP4,ARHGAP35,SOCS3,HSF4,ALDH5A1,BFSP1,BHLHB9,STAT6,PEX2,TLE1,PTBP3,OVOL1,SPTBN5,PLXND1,LIFR,ANXA3,SORT1,ARHGEF11,ARHGEF7,CIT,LRP4,TGFBR1,COL4A5,AES,ITGA2B,HDAC9,KIF5B,TOP2A,MDM1,ADRBK1,ADORA1,LLGL2,BMP7,MYCL,TOX2,KIAA0319,ACTA2,ARVCF,TRIM3,MTURN,RPGR,MYO5A,ADAM17,WNT10B,NR4A1,ASPM,RC3H2,MBNL3,TTC7A,RUNX3,FAM73B,FOXL1,LEPR,MAP1B,ARHGAP24,LEMD2,CD8A,SWAP70,PRCP,DHRS2,CTSV,SPINT2,CSGALNACT1,ARRB1,HOXB13,PLOD3,SOX8,ZMIZ1,L1CAM,AHR,NGEF |
| 2.551e-13 | -29.00 | intracellular organelle part | cellular component | GO:0044446 | 7812 | 1316 | 17570 | 2579 |
IBTK,SLC25A13,PNPLA2,HEXB,RET,CCNO,TRAPPC8,TGOLN2,DPP8,SNX9,NPM2,NAPG,MUC4,UBE2T,DNM2,PPP1CA,WBP4,CPE,MGAT5,DSTN,UXT,KDELR3,TFAP2C,PRKAR2B,GINS4,LCP1,ENPP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,HSPB1,STARD13,ANXA11,NXT2,GGA1,SEC61G,RAB23,COX6C,FAM21C,MARCH8,FLII,RAC2,ZCCHC17,FRY,ATP5H,FLRT3,RANBP1,FBXL14,PCYOX1,SLAIN2,CADPS2,USP1,MYDGF,MAPK7,MOXD1,NUP85,TTLL1,PPP6R1,MCCC2,REC8,MAPKAPK3,PYM1,ERO1A,FHL2,KIF20B,ELK1,GOLT1A,GNA11,PSMA4,SFXN5,FNTA,ETS2,DGAT2,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,DMPK,LFNG,APOO,MAPK4,MGST2,MVB12B,APPBP2,RCN1,MUC16,CDH1,XYLT2,ZNF365,MYT1,SNX10,ETV4,MX1,SNX8,SEC61B,ERMP1,COL6A2,AGPS,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,GTF2A2,COX20,GABARAPL1,CCNB3,SHROOM3,WFS1,PNPLA6,SLC25A30,MAPK12,MZT1,HSP90B1,GCAT,CKAP2,BACE1,TRAF2,DCAF7,ESRP1,BIK,SDC4,HABP4,FLOT1,CTSZ,IFT27,SLC25A43,NFAT5,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,GPC3,MGAT4A,FAM20B,CST3,TUBGCP6,KLC3,BAX,RAG1,MED22,PARP9,ACBD5,PLSCR1,TACC1,PIK3R1,MRS2,UBE2A,AK4,RAB3IP,LDLRAP1,RPL12,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,NR4A3,SSNA1,CMPK2,SRSF9,ACOT7,PHC1,EPAS1,ARFGEF1,LMCD1,NDRG2,DNAJB11,NENF,ITPR2,MGAT5B,SPTB,FANCI,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,P4HB,ARL1,PSMC2,SLC44A1,ABCA2,SCARA3,SMAGP,PLK1,THRB,KRT80,STAU2,CBX6,NFE2L1,CKAP2L,ARFRP1,EAF2,DZIP1L,KDM4D,HS6ST1,PLEKHG6,AGPAT2,KLF12,ZNF367,KPNA2,MYL12B,RRAGD,RUNX2,LMTK3,HJURP,LGALS3,FXYD3,PSMD7,RAB6A,B4GALNT1,MYO5C,TIMP1,KIF13B,TBCD,SLC30A6,SELK,FAR2,WNT3A,MPHOSPH9,CKAP4,MGAT4B,EMC2,SCRIB,PDK3,BCL2L13,CDK5R1,C18orf8,FA2H,COL13A1,P4HA3,ZDHHC7,PLD1,AKIP1,CCNB2,USP43,RAD21,HOXB7,TP53,P2RX7,RHPN2,BAHD1,STIL,PCBP1,EMP2,BCAP31,TTC21B,PDGFA,KMT5C,WDR44,TACC2,BCL6,PLK4,VAT1,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,DAG1,ATP13A2,PTGS2,TAPBP,IDE,RBL1,STK38,MAOA,CHMP4B,XRCC3,IRF7,ST3GAL1,FAM134B,ARFGEF3,CTDSP1,CMAS,PINK1,TAB3,CTSB,SCD5,MCTP2,CDCA8,ERCC6L,ERI2,GTF3A,HMGN3,LBR,AIP,VPS26A,PARM1,DNAJB9,H1FX,FZD6,M6PR,ZDHHC21,TBC1D31,GTF2F2,FAM63A,UBE2J1,TFAP2A,SGK1,ALDH7A1,HMGCL,GCNT1,P2RX4,HES1,RHOA,HMGN5,GUSB,PLAUR,PRICKLE1,MAML2,COL7A1,BBS2,TXNDC11,BCL10,DDX23,NEIL3,FGF18,E2F1,SH3BGRL2,PTGES,HIPK3,ZBTB33,GOLGB1,LAMP1,SLC35D2,TXN,PNISR,SSH1,HSPG2,CUL1,PSME1,SEPT4,PJA2,OAT,PICK1,SLC9A7,HELZ2,CYP1A1,STIM1,OSBPL3,POLL,IRF2,SNX16,HYLS1,MARCH2,ZBTB18,SPATA18,CDYL,BNIP3L,SLC35C1,KIF13A,POR,RAB2B,PRIM1,PPP2R4,CCDC97,RECQL,SCOC,TMEM55B,AKAP17A,TXNDC9,PSIP1,SH3RF2,CALR,DOPEY2,ZNRF2,RPL39,VASN,MSH2,TPST1,GPR161,PIGC,GID8,PRODH,GCC2,CEP89,LPGAT1,CALM1,WHSC1,ATP8B3,ANTXR1,JADE2,NFIB,PLEKHH2,FAM64A,FAAH,WDR19,AGBL5,PIAS2,FAM83D,ARAP1,APPL2,SFMBT1,CABIN1,SAMD8,ZBTB34,PLIN3,HOOK1,EHD1,SPRED1,KIF3C,DLGAP5,THRA,CERCAM,NDRG1,CCDC110,ATP2C2,BCL2L1,FLT3,CYP39A1,ZFYVE9,CD46,CCNA2,ACAP2,RNASEH2A,PDE4D,OSBPL7,TSPAN1,FLOT2,MED30,ATG4D,COG2,FOXJ2,UTRN,CLSTN1,KIF1C,RAD17,PYGO1,PKMYT1,B3GALNT2,ITPR3,TRIQK,ATP10D,CEP162,ZMPSTE24,DDOST,ACAD10,TRIOBP,SLC27A3,CBX7,COBL,DEPDC1,CENPI,NES,CBLL1,PLD2,FBXO6,SPDL1,DNAH3,HLA-A,COX7A2,SLC25A36,CKAP5,FUT8,DRAM1,CD9,CITED2,MSH6,TGIF1,PDGFC,ZWINT,ALDH2,B3GNT2,PAPD7,ZC3H11A,DIAPH2,YES1,AIF1L,FOS,ARSK,KIF11,CPTP,CRTC2,DCTN6,ACADSB,FGFR2,ERAP1,WDR62,FZD5,ESPL1,CCNC,FAF2,CRYM,MPP5,MAP1LC3B,SLC8B1,ERP29,ECI1,TRIM68,ZFYVE16,RAB15,CDKL5,SIVA1,CEP78,ASH2L,CTTN,MYRIP,STK35,LAMP3,CERS2,CYP1B1,CXXC5,CENPA,LAP3,ASXL1,ACBD3,MAN2A2,GPRC5B,HPSE,TDRD7,GLA,CHPT1,NRGN,NR2C2,PCSK5,LASP1,PPP1R12A,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,CES2,OCRL,COL6A1,SUCO,PRKCI,SRP54,HLA-C,ZRANB1,ETV7,GAD1,SNX7,TPGS2,ELK3,NUBP1,PDIK1L,C3orf58,RANBP9,STEAP1,SOX13,INSR,UAP1,TMEM30A,RAB31,CTSA,SHROOM2,APOL2,COL16A1,RARG,DRD1,CCNE2,DYNLRB1,SORBS1,PAX6,HDAC11,SOD2,PDIA5,COL18A1,SAYSD1,PHLDA1,EXT2,SAP130,CYP4F11,COX14,KIF14,REEP1,ECE1,NFKB2,ETHE1,UPF3A,EBAG9,SEPHS1,CHP1,SOAT1,C3orf52,MRPS35,TMTC2,CDC25C,FANCE,CASP4,PDHX,HSF4,JADE1,ALDH5A1,STAT6,TLE1,SPTBN5,MAD2L1BP,KDELC2,GLIS3,FBLIM1,SH3D19,SHPRH,COL4A5,INTS8,HMGXB4,ITGA2B,HDAC9,TMEM63A,KIF5B,TOP2A,MZT2A,CARD8,TAF1B,LLGL2,A4GALT,TOX2,RRBP1,ZDHHC13,H2AFY,CLIP2,RPGR,SLC35A1,MYO5A,B3GALT6,SYBU,RC3H2,RGCC,RUNX3,LEMD2,CTSL,CASP7,RND3,TRIM69,CTSV,RAP2C,CSGALNACT1,ARRB1,MCUR1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,DOC2A,ACACB,TRIM24,IL15RA,ADD1,AASS,MRPS15,DNAJC3,SMARCAL1,XIAP,DHX8,CNTROB,MORF4L2,SYTL4,KIF26A,BARD1,PHF1,TP73,DAPK2,CALM2,WEE1,ZYX,RGS12,AP1M2,PSMD1,PQLC2,DNAH6,CYP2S1,CABP1,RDH14,FUT1,TUBG1,ACOX2,APOBEC3G,ODF2L,ERAP2,TUBA4A,VPS11,SMARCA2,SPEF2,TNIP1,SPRTN,MTRF1L,LOXL2,ICMT,MYOM1,CYP4F3,COL12A1,CAMK2N2,WDR11,DNM1L,LIMK1,MYLK,MAP3K11,MRPS28,ARF6,PDPR,ALDH6A1,FAM169A,NUAK1,CYP2J2,SOX9,SLC36A4,LMNA,GNS,DNPEP,NEK2,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,NAGPA,UFD1L,KIF20A,SALL4,STAT4,MYBL2,PLS1,SRSF5,ILK,MEST,TP53INP2,SPTLC2,RHOB,DCP2,CYB5A,DHX32,NCOA3,SCARB2,HTT,TIMM8A,SETD3,ITPR1,AURKA,DYSF,MDH1,ALG2,B4GAT1,NDE1,ARPC2,RPS6KA3,CCDC109B,GRHL2,TUBB4B,GALNT12,ACTR8,ETNK1,RGS20,TESK2,PKP2,NUF2,PRKACA,APC2,KTN1,CDS1,CCND1,SCNN1A,SP100,DACT1,ACSL4,RAB27B,ARL4D,CDKN2D,TMEM9,RNF169,CAMSAP3,PSRC1,NRBF2,FZD4,SYNE2,NUSAP1,CDCA2,PXYLP1,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,GEN1,ARNT,TTC8,TAOK2,MAN1A2,RASSF7,PDIA3,GMCL1,PKN1,NUCB2,TMA16,ETS1,NEO1,PDIA4,DTX3L,CAPN2,ADD3,IRAK1,CTSC,ARSG,ANKS1B,ALG13,CALD1,FDXR,PLEKHF1,TMBIM6,ECI2,MAPK11,AK3,ITM2C,TPCN1,S100A6,TMX1,CRTAP,MOB4,LCA5,FMN1,BCL9,ELOVL3,EIF5A2,PLEKHA7,FAM109A,SKA1,GALNT3,NR1D2,ATXN7L3,ARFGAP3,HMGA1,CENPE,NUP37,USF2,FOXA1,MYL9,UNC93B1,AGRN,CUL4B,EPHA4,SUDS3,NDC80,MCCC1,CDIPT,HDAC6,PDGFB,NUP62CL,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,PXMP4,TRAM1,CCDC38,PCGF5,ING1,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,RHEB,OPTN,DPYSL3,MSL1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,TTC9,PIEZO1,POMT1,MAFF,PRKAA2,BMF,CHCHD7,HLA-F,ASAH1,RACGAP1,B4GALT4,DHRS3,PGAP1,SSX2IP,CORO1B,RB1,DAZAP1,GATA2,PAK2,MDFIC,TMEM8A,ALDH3A2,PSMA5,C9orf9,CYP26B1,CHSY3,MRPS33,SPATA13,KBTBD8,TCF7,ZDHHC3,G2E3,SMN1,MOSPD3,EPN3,MAPKAPK2,COQ10A,H1F0,MFSD2A,TMEM120A,CTBP1,NF2,UPF3B,FOXM1,P3H2,XYLT1,ERBB2,CCNL1,FAM198B,LPIN3,CYP26A1,SDF4,PER2,ATP6V0B,N4BP3,EGLN3,MINPP1,FAR1,GM2A,SIRT1,CPD,EVA1A,TCEB2,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,PSMD3,RPL22,LTA4H,AIFM3,POMGNT2,NDST3,CNEP1R1,ZC3HC1,COPG1,GSDMD,MAN2B2,COL9A3,GOLIM4,PACSIN2,TRAPPC10,CD63,BLVRB,SWI5,PSMD10,NKRF,CRABP2,DSE,CCDC92,CEP97,SLC35B4,BUB1,ABCD1,KLF9,HEXIM2,CAMK2G,MLEC,PSMB4,NR3C1,IFITM3,AMFR,LITAF,PPARA,CARD19,FXR2,FNDC3A,BCAR1,MAPK8IP1,FUCA1,SERPINA1,CDCA7L,NMI,PGRMC1,PPP2R3C,PKD2,ACADM,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,SUN1,GAA,ATP8A1,FAM129B,KLC2,TAP1,GATA3,CCNB1,FAM101B,RIC1,CENPN,NCS1,CHST2,RGS3,STEAP2,PACSIN1,TFG,LAMP2,LOC81691,KIFC2,SNTB2,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SLC25A5,ULK2,SGPP1,AHRR,SFXN1,KDSR,SLC25A4,AREG,PLK2,GNPTAB,FAM110C,SARAF,TRAF5,RTN3,DLAT,MRPL44,HLA-E,DGKQ,SLC25A27,KIF23,NDUFA4,NOTCH2,SLC1A3,KIAA1161,BMP2K,MECOM,SNX18,NECAB3,BDH1,SORL1,PIKFYVE,CTSD,TMED2,EEF1D,FAM69A,DNAI1,FADS2,QSOX1,B3GNT7,PMPCB,DDB2,MMD,B9D2,VEZT,KDM3A,DGKH,PRKAG2,NR4A2,MAP3K5,NRBP1,IRF1,PLA2G4A,ELK4,SLC2A4,CEP70,ARMCX3,TRIP10,NLRX1,RPS6KA1,SUZ12,IQGAP1,SNN,AIFM2,GNB2,MNS1,SLC25A35,CYHR1,CDKN1B,TNPO2,LGMN,NR2C1,TMBIM1,GPX4,MYO5B,CDKN2AIP,SEC23A,TMEM43,CAPN6,DMTN,LYRM1,TEP1,COX11,SLC11A2,H2AFV,SP4,NIN,FYN,ZNF641,PPP2R5A,STK26,CFAP45,STAT1,PPP1CB,SLC27A1,RAB29,KLF5,HS3ST3B1,B4GALT3,NR3C2,MRPS9,ATP9A,SPR,TEAD3,AKIRIN1,FAM111A,PHF7,OXCT1,PTEN,PPP1R10,MGAT1,CENPJ,PRC1,SLC44A2,ERCC2,MAP3K7,CNPY3,GFI1,SPRY2,NCOA2,SMC4,PCCB,CASK,PARP4,VAMP3,FURIN,C1GALT1C1,GPLD1,NUCB1,CTNS,PRDX3,SLC25A40,CSTF2,GPER1,NCAPG2,ARSB,SLC25A38,ESYT2,JARID2,CASP3,CPT2,UBE2Z,TAF6L,KIF2C,SH3KBP1,TSEN34,ABCD4,CHPF,MAGOHB,GRHL1,ZCCHC12,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,ANKRD12,SUN3,KIF22,RAB20,RP2,MYH14,NFU1,TECR,RASGRP1,ATL1,SOD1,TRIM8,SYNE3,FOPNL,MRPS18A,PTGFRN,MRPS36,TCN2,NEIL1,TRIM45,IARS2,RAP1GAP,PPP2R5D,PSMC1,STARD3NL,PIFO,PEX6,ELOVL7,KNTC1,ACAD8,LRIF1,HP1BP3,KDELR1,OXR1,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,FECH,GNAS,TSC1,NUDT16,PLPP3,UTP14C,CDCA5,PAPD5,KIF12,GAS2L1,SLC25A24,SPC25,IL15,PSME2,SLC2A8,MORC4,ZMYND10,MICALL2,LRRC45,SLC25A48,SS18,SETDB2,SMO,RPN2,STEAP3,PDIA6,HSPA2,TAF5,KREMEN2,OSTM1,AP5M1,ERBB2IP,DUSP4,SNAPC2,BFSP1,PEX2,CANT1,CYP2U1,SGOL1,REEP4,CBX4,ANXA3,CDS2,SORT1,POC1B,JKAMP,POMGNT1,SAC3D1,IRF2BPL,SNX13,GALNS,KIAA0319,CKS1B,BRD7,SYPL1,SUN2,RAB3B,CENPC,NR4A1,ASPM,OGDHL,POLD3,MPV17L2,SPAG1,MAP1B,HLA-B,MARC1,HNRNPH2,DHRS2,UBE2D2,TADA2B,GLB1,HOXB13,GEM,ATP6V1C1,SOX8,SNPH |
| 2.782e-13 | -28.91 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | 352 | 104 | 17758 | 2588 |
UNC93B1,CEP70,UGP2,HEBP1,CAST,DNAJC3,TSC22D3,HEXB,PKP2,PLAC1,PLA2G16,SEPT4,TTC21B,PDGFA,FAM46A,CTGF,ARTN,UBE2T,KLF3,AOX1,STEAP2,APIP,TMEM37,EGLN3,PDIA6,FAR1,CTDSP2,CCDC38,SULF2,PCGF5,C6orf1,KIAA0040,SERTAD4,BNIP3L,HTATIP2,LOXL2,DUSP4,PRKRA,IDH1,STK17B,ENPP1,TAPBP,WDR11,WIPI1,RBL1,STAT1,NFKBIZ,RBM43,SGOL1,MIIP,DENND5B,GRN,FBLIM1,MZT1,HJURP,FLOT1,FBXO6,FGF19,TSPAN17,TMCC3,PDIA4,FAM111A,E2F7,DNPEP,ANK1,CYR61,SPIN4,PFKL,COL6A1,ZIC5,SGK1,TRIM21,PLEKHF1,BUB1,MXD3,KLF9,PIM1,AK3,CNOT6L,CASD1,NCOA2,FAM69A,MOSPD2,PQLC3,TBC1D8B,UBE2A,PDE5A,GGH,PIM3,SRSF5,BLVRA,FOS,C4orf27,RHOB,PRKAG2,H1F0,RND3,NR1D2,PLD1,TMEM159,CEP41,SHOX2,CYBRD1,DCBLD1 |
| 3.218e-13 | -28.76 | cellular component organization | biological process | GO:0016043 | 5336 | 953 | 16441 | 2455 |
DOC2A,ACACB,ADD1,GRIK2,MRPS15,AASS,TRIM5,AK7,PNPLA2,HEXB,RET,CACNA2D2,XIAP,CCNO,NRG2,TRAPPC8,CNTROB,MORF4L2,SYTL4,SNX9,CARD10,LTBP3,PHF1,TP73,NPM2,CALM2,WEE1,NAPG,ZYX,PHYHIP,PSMD1,AP1M2,TGFBR3,DNM2,TUBG1,SEMA3G,TIAM1,CPE,TUBA4A,DNAAF3,NEK4,SPEF2,VPS11,SMARCA2,DSTN,UXT,CDA,MTRF1L,PRKAR2B,LOXL2,ICMT,MYOM1,ARF4,GINS4,LCP1,COL12A1,ABR,PLCG1,MID1IP1,DNM1L,LIMK1,TRAF3IP1,MYLK,NOD2,HDAC1,MRPS28,TMOD2,ITPKA,ARF6,SCN5A,SEC61G,ITGA6,SOX9,RAB23,GPSM2,MERTK,LMNA,ATG4A,ELF3,TFAP4,FLII,RAC2,ZCCHC17,FRY,RIMS3,MEGF8,FLRT3,FBXO7,FAM13B,NEK2,SLAIN2,ALPK1,PANX2,NCAM1,NUP85,TTLL1,PPP6R1,NAGPA,REC8,HPS3,KIF20A,PYM1,ERO1A,SHARPIN,MYBL2,PLS1,KIF20B,SRSF5,NPHP3,ILK,TP53INP2,DPYSL4,PSMA4,RHOB,PLIN5,PTPRF,NCOA3,FNTA,MTFMT,TIMM8A,HTT,SEMA4D,SETD3,TEX30,AURKA,DYSF,CLMN,MDH1,B4GAT1,NDE1,ARPC2,CFAP20,TRPC3,NUP58,RPS6KA3,DMPK,MTM1,GRHL2,TMSB15A,TUBB4B,LFNG,ACTR8,APOO,PTTG1,C5orf30,WDTC1,TESK2,PKP2,NUF2,PRKACA,CCND1,CDH1,SP100,DACT1,ACSL4,DLG3,RASGEF1A,ETV4,SNX10,SNX8,CAMSAP3,SSH3,SEC61B,PSRC1,COL6A2,FZD4,SYNE2,CYS1,VPS4B,SYP,CDCA2,NUSAP1,RAB38,GTF2A2,TANC1,SNX12,COX20,GABARAPL1,IRS2,PEX5,PDLIM3,SHROOM3,CORO1C,SLC9A6,AXL,SIPA1L1,WWTR1,RGS14,MAPK12,TTC8,CTHRC1,FARP1,TAOK2,HSP90B1,TRAF2,CCM2,BIK,SDC4,FLOT1,CTSZ,ANO9,PKN1,PLPPR4,KCNC4,ETS1,IFT27,TSPAN17,ICAM1,NEO1,DTX3L,ANK1,PDCD10,ITGB8,IGSF9,IRAK1,CTSC,FAM160A2,CST3,TUBGCP6,BAX,PLEKHF1,ADAM15,MAPK11,RAG1,S100A6,CRTAP,ACBD5,PVRL4,ADAMTS2,LCA5,PLSCR1,TACC1,FMN1,RAPGEF2,GRIN1,UBE2A,PLEKHA7,EMP3,RAB3IP,FAM109A,SKA1,CRISPLD2,ABLIM2,CNTNAP1,RPL12,PLOD2,ATXN7L3,SYT7,SLC35B3,NR4A3,SSNA1,ITGAV,HMGA1,CENPE,NUP37,WDR45B,SRSF9,FOXA1,PHC1,TLL2,MYL9,AGRN,EPAS1,CUL4B,EPHA4,SUDS3,ARFGEF1,NDC80,LMCD1,F11R,HDAC6,PDGFB,SDC1,SPTB,SLC9A3R2,INPP5E,PCNA,RPS6KA2,NUP210,CTNNB1,NPNT,SHC3,P4HB,CNTRL,ARL1,PSMC2,MITF,NTN4,TLN2,ANO4,TRAM1,NEB,ZNF462,PLK1,KCNIP3,MARK1,ING1,CELSR2,CBX6,C12orf65,EZR,ARFRP1,ANLN,CDK1,VCP,OPTN,DZIP1L,DPYSL3,KDM4D,MSL1,MAP2,WIPI1,PRKCDBP,CTNND1,POMT1,TC2N,MYL12B,PRKAA2,USH1C,LGALS3,HJURP,RASA2,PDCL,PSMD7,SORBS3,RACGAP1,NCKAP1,CNTNAP2,FBLN1,SSX2IP,CORO1B,BMP2,RB1,VASP,TIMP1,IGF1R,PAK2,TBCD,FCHO1,EXOC8,NTN1,WNT3A,PSMA5,CYP26B1,DPYSL5,MRPS33,TESK1,RGMB,CORO2A,SPATA13,STRADB,SCRIB,ZDHHC3,SMN1,NMT2,CDK5R1,FA2H,H1F0,COL13A1,PVRL2,ITGA7,ZDHHC7,LTBP2,ATP1B3,TMEM120A,AKIP1,SEMA3A,CCNB2,CDAN1,IFI6,CTBP1,RAD21,NF2,P3H2,TP53,P2RX7,ERBB2,RASGRP3,BAHD1,STIL,EMP2,BCAP31,TMSB15B,SYTL2,PER2,TTC21B,PDGFA,ATP6V0B,KMT5C,SRPX,TACC2,SRR,BCL6,PLK4,ZDHHC23,CDH3,ESPN,LMAN1,SULF2,CTH,PPIF,SIRT1,CLCN3,TIMP2,MBP,TCEB2,AKT1,FIGNL1,S100A4,CDC20,MYL12A,DAG1,TAPBP,RTN4RL1,IDE,RBL1,PSMD3,PTK7,ADAMTS14,CHMP4B,XRCC3,EFNA5,SYT13,ARHGAP4,RPL22,CNEP1R1,ZC3HC1,COPG1,FAM134B,BIN1,COL9A3,PINK1,PACSIN2,TRAPPC10,KLHL13,CTSB,CDCA8,ERCC6L,PSMD10,HMGN3,CRABP2,AIP,H1FX,NRP2,GBX2,ZDHHC21,CEP97,CDK16,SGK1,TRIM21,BUB1,HMGCL,ABCD1,CAMK2G,P2RX4,HES1,FBLN5,RHOA,HMGN5,PSMB4,NR3C1,CRB3,AMFR,STMN3,COL7A1,CAPNS1,BCAR1,BBS2,BORA,BCL10,DDX23,PRDX4,SERPINA1,FAT4,FGF18,PGRMC1,PPP2R3C,PKD2,SPCS3,UBE2C,TBC1D4,ARHGEF4,GOLGB1,SUN1,GAA,CFAP74,SSH1,HSPG2,ATP8A1,GATA3,PSME1,PLXNA1,CCNB1,SEPT4,OAT,FAM101B,CENPN,PICK1,PAK6,TYMP,CTGF,ELMO2,KCNS3,PIK3CA,TFG,PACSIN1,XKR8,SPATA18,ACVR1C,PBK,CASP9,CDYL,BNIP3L,SLC35C1,AGO4,KIF13A,TNS1,PIF1,AURKB,CCNF,MCFD2,ARHGEF26,ULK2,PRIM1,SLC25A4,AREG,PLK2,GNPTAB,PPP2R4,PRDM5,BMP1,UNC5B,F2RL1,RTN3,FGD1,SEMA6B,KLF2,RECQL,MRPL44,INPPL1,DHPS,TBC1D1,PRKAA1,KIF23,SLC1A3,APBA1,PSIP1,MECOM,CALR,DOPEY2,ITGA3,CYR61,SNX18,RPL39,MSH2,PRKG1,TNFRSF12A,CACNA1D,PIKFYVE,CTSD,MAST4,KCTD3,SYTL3,TSPAN33,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,KCNJ12,GCC2,CEP89,B9D2,CALM1,ANO6,WHSC1,EPHA1,ATP8B3,KDM3A,ANTXR1,JADE2,NFIB,RASA1,STX3,FAS,DGKH,MMP15,PLEKHH2,PRKAG2,FAM64A,WDR19,ZDHHC20,MATN2,ARAP1,FAM83D,FGD6,SFMBT1,NR4A2,KLK7,CABIN1,EFNA1,HOOK1,EHD1,ELK4,SPRED1,KIF3C,SLC2A4,CEP70,DLGAP5,TCTN2,REPS2,ST14,TRIP10,RPS6KA1,IQGAP1,NDRG1,SUZ12,FTH1,KCTD12,BLCAP,BCL2L1,AIFM2,DDR1,MNS1,ZFYVE9,APLP2,CCNA2,TNPO2,DAB2IP,PDE4D,EPHB4,FLOT2,GPX4,ATG4D,SEMA3B,SEC23A,COG2,TMEM43,CAPN6,DMTN,TEP1,COX11,PRKCQ,SLC11A2,ATP1B1,PKMYT1,PYGO1,ITPR3,AKR1E2,ALCAM,H2AFV,ATP10D,FZD7,NIN,CEP162,ZMPSTE24,EPHA10,FYN,JAK1,DDOST,STK26,TRIOBP,KLF5,NRG1,RAB29,MLKL,COBL,CBX7,ATMIN,PRKAR1A,MRPS9,WASF3,PLSCR4,ATP9A,CENPI,EPS8,CDCA3,NES,PLD2,SPDL1,SPR,EFNB1,FGF19,SIX4,RND1,SLC25A36,CKAP5,SNTA1,PTEN,CENPJ,PRC1,CD9,ATP8B1,ERCC2,ERBB3,MAP3K7,SPRY2,MSH6,NCOA2,SMC4,FARP2,PDGFC,RASGRF1,ZWINT,SHMT1,B3GNT2,CASK,ARHGEF28,PAPD7,FURIN,VAMP3,C1GALT1C1,DIAPH2,YES1,KIF11,CRTC2,DCTN6,FGFR2,PRDX3,RYK,SERPINB5,GRIN2D,GPER1,WDR62,NCAPG2,ARSB,ESPL1,OCLN,USP16,RGMA,JARID2,EMX1,LTBP1,CASP3,UGT8,FAF2,ST13,MPP5,KIF2C,TAF6L,CACNB4,MAP1LC3B,DNER,SH3KBP1,ZFYVE16,RAB15,LRRC6,CDKL5,DPYSL2,CEP78,DLG1,CAPG,TRPC1,SUN3,KIF22,RAB20,ASH2L,RP2,MYH14,NFU1,CTTN,BTBD3,IL1RAP,RASGRP1,CYP1B1,OLFML2A,ATL1,SOD1,CENPA,ASXL1,SYNE3,STRIP2,FOPNL,RNF165,ARHGDIB,MRPS18A,MRPS36,PTGFRN,TYSND1,IARS2,PSMC1,CAPN1,NR2C2,PIFO,ARAP3,PPP1R12A,SERPINE2,PEX6,BVES,ETV5,ASL,ATP6V1E2,CALM3,ADAMTSL4,DUSP5,SPP1,LRRN2,PFKL,OCRL,KCNN4,COL6A1,PRKCI,FXYD5,SRP54,LIMCH1,KNTC1,ZRANB1,SLC12A2,ALS2CL,CCDC88A,SNX7,HP1BP3,VWA1,HMG20B,FBXO8,NUBP1,RANBP9,EGFR,FECH,TSC1,ONECUT1,INSR,TMEM30A,PAPD5,CDCA5,RAB31,PITPNA,SHROOM2,JAK3,COL16A1,RARG,SNX30,KLF7,DRD1,FBXW5,GAS2L1,DYNLRB1,LZTFL1,SORBS1,SPC25,SLC2A8,PSME2,HDAC11,SOD2,COL18A1,MRAS,TDRKH,ZMYND10,MICALL2,PATL2,KCTD9,SAP130,SS18,KCTD15,ARTN,SETDB2,COX14,ZDHHC12,KIF14,FRYL,REEP1,SMO,RPN2,EPB41L4B,NFKB2,F2R,LOXL1,HSPA2,FRS3,CHP1,CKS2,SOAT1,GCA,BAG4,TAF5,MRPS35,ERBB2IP,CD40,CDC25C,KCTD2,ARHGAP35,JADE1,HSF4,ALDH5A1,PEX2,SPTBN5,PLXND1,SGOL1,REEP4,ABCA1,LIFR,PPP2R2D,CBX4,FBLIM1,GCLM,SORT1,TSPAN15,ARHGEF11,SH3D19,CIT,SHPRH,ARHGEF7,FRMD6,POC1B,LRP4,TGFBR1,COL4A5,HMGXB4,ITGA2B,HDAC9,SAC3D1,KIF5B,TOP2A,ADORA1,TAF1B,LLGL2,A4GALT,BMP7,TOX2,H2AFY,IQGAP3,RPGR,MYO5A,SUN2,ADAM17,RAB3B,CENPC,CFAP46,ASPM,GCLC,POLD3,MPV17L2,SPAG1,MAP1B,LEMD2,CTSL,CASP7,SWAP70,RND3,CTSV,SPINT2,RAP2C,CSGALNACT1,TADA2B,ARRB1,GEM,ATP6V1C1,ZMIZ1,PLOD3,CEP41,L1CAM,ABCG1,NGEF |
| 3.286e-13 | -28.74 | HAN_SATB1_TARGETS_DN | MSigDB lists | HAN_SATB1_TARGETS_DN | 420 | 118 | 17758 | 2588 |
MYL9,LTBP1,LZTFL1,ST13,PAPSS2,HOXB7,EPAS1,NDRG1,CD82,MCOLN3,TAP1,IL18,PLAC1,PDGFRL,AIFM2,AP1M2,RPS6KA2,CTNNB1,CDH1,FICD,PPME1,PHTF1,MITF,ATP13A3,CDH3,ARNT2,PIK3CD,PDE4D,OAS3,PTPRE,HSPA2,NAGA,TUBA4A,CPD,MX1,MBP,COL6A2,LGALS8,FZD4,OSTM1,SEPT6,TFAP2C,TNS1,CD40,TP53I3,CASP4,SEC14L2,ATP13A2,LRRC42,PTGS2,FYN,C19orf66,RAB11FIP1,SH3GLB2,KLF5,PDXK,PPP2R2D,MAFF,DENND5B,PCSK5,FAM134B,WASF3,CDS2,PACSIN2,ENO2,ZCCHC24,ASL,CTSZ,COL4A5,SBF1,IL18R1,DNAJB9,NEO1,SGPL1,M6PR,B3GALNT1,TAF1B,ALG13,CALD1,SORL1,MAPK11,LIMCH1,CITED2,ULBP2,TPCN1,RIMS2,DUSP1,CYP26B1,RASGRF1,NR3C1,RC3H2,AK4,IFIT3,ANTXR1,FBXO10,ZDHHC3,STX3,RHOB,PTPRF,TSC1,DDAH1,NCOA3,PRKAG2,CASP7,RAB11FIP2,PLOD2,RND3,PELI2,SLC2A6,MATN2,ITPR1,ARFGAP3,OSMR,FHL1,JAK3,APOL2,RARG,KLF7 |
| 3.372e-13 | -28.72 | CHEN_METABOLIC_SYNDROM_NETWORK | MSigDB lists | CHEN_METABOLIC_SYNDROM_NETWORK | 1167 | 259 | 17758 | 2588 |
LGR4,FAM129B,HEXB,PDGFRL,NANS,LTBP3,SLC35E4,CALM2,CDKN2C,OSBPL3,MTMR11,SEMA3G,IL10RB,LAMP2,TNIP1,PIF1,LOXL2,LCP1,ABR,PLK2,LRIG1,SERPINB6,UNC5B,TRAF5,F2RL1,E2F8,FRMD4A,TBC1D1,LMNA,ELF3,GNS,CALR,RAC2,PIK3AP1,CD22,VASN,OPN3,TMEM51,TPST1,OSTF1,CADPS2,CTSD,MAPK7,TSPAN33,PRODH,MFI2,STAT4,ANO6,CALM1,FHL2,NPC2,SPTLC2,ANTXR1,RASA1,MAGED2,CACHD1,FAM64A,SEMA4D,DCK,MATN2,SLC4A3,ARAP1,FGD6,DYSF,CDK18,ARPC2,PLA2G4A,SPRED1,SLC2A4,CCDC109B,NQO1,S100A11,INPP5D,CERCAM,C5orf30,CD274,SNN,FLT3,ZNF385B,CDS1,RCN1,APOBEC3B,SCNN1A,CCNA2,SP100,TAX1BP3,LGMN,RASGEF1A,DLG3,SEMA3B,PSRC1,ERMP1,TMEM43,PLEKHO1,TEP1,TMEM144,KIF1C,SLC11A2,SYP,PKMYT1,TANC1,ITPR3,NIN,ALDH3B1,NGFRAP1,WFS1,NRG1,RGS14,SLC27A3,PCOLCE,EPS8,CDCA3,SRPX2,HOXB2,LGALS3BP,SGPL1,SLC25A36,CAPN2,RASSF8,FAM111A,CXCL16,OXCT1,SLC27A6,RNF128,CD9,DRAM1,IGFBP2,TAGLN2,ITM2C,S100A6,ADAMTS2,PLSCR1,LONRF3,FMN1,EMP3,BLVRA,FOS,GPLD1,GALNT3,LDLRAP1,DGCR2,ACVRL1,PPM1H,FHL1,HMGA1,WDR91,FZD5,ESPL1,UNC93B1,LTBP1,PPM1J,CAMKK1,NDRG2,DNAJB11,BTG3,RAB15,RPS6KA2,PCNA,TSPAN6,CAPG,DUSP10,TNFRSF18,KIF22,PTPRE,PTPN18,CENPA,CBX6,C12orf65,ARHGDIB,SESN1,STK17B,DPYSL3,TMEM164,TTC39C,MYL12B,GRN,LASP1,LGALS3,CHCHD7,UBASH3B,ASL,CALM3,ASAH1,DOCK11,DUSP5,CA2,RINL,KCNN4,COL6A1,FXYD5,AHCY,C10orf54,MDFI,C9orf9,BCL2L13,IFIT3,STEAP1,SLC6A6,SLC2A6,RAB31,LTBP2,COL16A1,USP43,GAS2L1,SLC25A24,FAM198B,ATP6V0B,SRPX,PLCG2,CDH3,VAT1,NFKB2,FAR1,LOXL1,SOAT1,SUSD3,C3orf52,IGSF8,ATP13A2,ABHD12,ARHGAP4,AKNA,REEP4,GSDMD,CMAS,ANXA3,SORT1,CD63,CTSB,FRMD6,HAL,GNE,BLVRB,ARMC7,DSE,NRP2,SIRPA,GALNS,SYK,MYO5A,GCNT1,P2RX4,FBLN5,GUSB,PLAUR,SYBU,LITAF,PRICKLE1,NPDC1,BCL10,CD83,ENDOD1,PRCP,GLB1,ATP6V1C1,ICOSLG,L1CAM,RAB3IL1,ABCG1 |
| 3.525e-13 | -28.67 | RUTELLA_RESPONSE_TO_HGF_UP | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_UP | 401 | 114 | 17758 | 2588 |
LAMP1,CASP3,TXN,NQO1,TRIP10,SUZ12,NDRG1,APOO,HEXB,SOD2,RASGRP3,IL18,FTH1,TEX2,PLXNA1,BCAP31,CCND1,ZFYVE16,IL6ST,ATP13A3,MITF,AKR1B1,VAT1,RAB20,TFG,SNX10,GM2A,SEPHS1,LAMP3,CYP1B1,LAMP2,CPD,DOCK4,PPIF,TIMP2,MCTP1,FOXJ2,ACO1,SLC11A2,RAB38,LHFPL2,ADRBK2,OPTN,DUOX1,FASTKD1,JAK1,RBM47,STAT1,MAOA,PDXK,GLA,HSPB1,ST3GAL1,GCLM,CDS2,PACSIN2,PINK1,MPZL1,LGALS3,PPP1R12A,CD63,TBC1D1,CTSB,SDC4,C6orf106,ASAH1,SLC1A3,C3orf18,DUSP5,SGPL1,GNS,TNS3,SPP1,MDM1,LYPD3,SLC16A6,BHLHE41,TPST1,TMEM51,CD9,TMBIM6,SGK1,KLF9,CTSD,ALDH3A2,FAM69A,FAH,WBP5,GFPT1,SUN2,LITAF,GGH,SNTB1,CYB5A,STK17A,IL1R1,NCOA3,SCARB2,PVRL2,NAT1,ITPR1,NETO2,NR4A3,ARFGAP3,MDH1,LTBP2,ATP1B3,ATP6V1C1,FZD5,PLOD3,TBC1D4,CD81,IFI6,ABCG1 |
| 4.380e-13 | -28.46 | MODULE_54 | MSigDB lists | MODULE_54 | 253 | 82 | 17758 | 2588 |
ARHGAP11A,CCNE2,TRIM24,DLGAP5,NQO1,FOXM1,PTTG1,NDC80,NUF2,KIF2C,CCNB1,BARD1,APOBEC3B,CDKN2C,PCNA,CCNA2,UBE2T,CDH1,IMPAD1,KIF14,PLK4,MANF,OAS3,PXMP4,TUBA4A,CKS2,PLK1,PSRC1,CENPA,PBK,CDC20,NUSAP1,AURKB,PKMYT1,CCNF,ANLN,SLC25A5,CDC25C,CDK1,PRIM1,KPNA2,MAPK13,E2F8,ZC3HC1,HJURP,CDKN1C,DEPDC1,CKAP2,KIF23,GPSM2,LBR,CTNNBIP1,TOP2A,RANBP1,MSH2,NEK2,CKS1B,TNFRSF12A,BUB1,AHCY,KNTC1,GAD1,SMC4,HMMR,ZWINT,ASPM,MYBL2,GGH,AIF1L,KIF11,PRDX4,FAM64A,NEIL3,CDCA5,FAM83D,E2F1,AURKA,CENPE,HMGA1,UBE2C,CCNB2,MELK |
| 4.391e-13 | -28.45 | regulation of kinase activity | biological process | GO:0043549 | 874 | 209 | 16441 | 2455 |
CCNC,CASP3,TXN,IBTK,DNAJC3,CAMKK1,EPHA4,NRG2,PSME1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,SHC3,RGS3,PSMC2,PIK3CA,DLG1,DUSP10,RASGRP1,PLK1,NEK4,SOD1,PRKAR2B,CDK1,PLCG1,CAMK2N2,GPRC5B,MADD,NOD2,MAP3K11,CAB39,HSPB1,PSMC1,GAB1,PIFO,CDKN1C,UBASH3B,RASA2,PRKAA1,PSMD7,CALM3,DUSP5,BMP2,TFAP4,RAC2,RB1,IGF1R,CYR61,FBXO7,PAK2,MAP3K9,SORL1,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,SOCS5,MMD,MAPKAPK3,CALM1,STRADB,PDE5A,EPHA1,ILK,PSMA4,EGFR,RASA1,CDK5R1,MAPKAPK2,TSC1,PRKAG2,INSR,CSF1,NLRC5,STK39,EFNA1,MAP3K5,JAK3,DRD1,CCNE2,SPRED1,AVPI1,NF2,IQGAP1,PSME2,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,FLT3,EMP2,STIL,PDGFA,CCND1,APLP2,CCNA2,RALB,KIF14,CDKN1B,DAB2IP,RASGEF1A,CDKN2D,F2R,HSPA2,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,PSRC1,RIPK2,AKT1,NRBF2,FZD4,PFKFB2,COX11,PKMYT1,DUSP4,CD40,CDC25C,MAP3K6,SOCS3,IRS2,FYN,PTPRJ,JAK1,PPP2R5A,CCNB3,STK26,RBL1,PSMD3,STK38,CORO1C,WWTR1,KIAA1804,SLC27A1,EFNA5,NRG1,SPTBN5,RGS14,PRKAR1A,PINK1,TAOK2,NKX3-1,TAB3,TRAF2,SDC4,PSMD10,HERC5,TGFBR1,PKN1,TRIB2,GSTP1,FGF19,DIRAS3,PDCD10,ADORA1,IRAK1,PTEN,BMP7,BAX,CKS1B,H2AFY,MAPK11,HEXIM2,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,DUSP1,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,PIK3R1,GRIN1,RGCC,MAPK8IP1,CDK5RAP1,FGFR2,PRDX3,FGF18,RAP2C,ARRB1,PPP2R3C,GRIN2D,PKD2,CENPE,FZD5,CD81,UBE2C,HIPK3,PKIA |
| 4.396e-13 | -28.45 | RAF_UP.V1_UP | MSigDB lists | RAF_UP.V1_UP | 188 | 67 | 17758 | 2588 |
UGT8,CEP70,EPAS1,GALNT12,CAST,XYLT1,NDC80,MORC4,KCTD12,PLS3,MTMR11,ACSL4,PDE4D,SCARA3,HSPA2,GM2A,SMAGP,CYP1B1,SGCE,CAPN6,SEPT6,SYNE2,SAT1,PTGER4,DUSP4,SGPP1,OPTN,FYN,ACYP1,ANKRD6,PTER,DHTKD1,SERPINI1,SLC31A2,GCLM,ARHGEF3,NUAK1,ITGA6,ETV5,GNE,HERC5,NTAN1,CAPN2,GATA2,ALPP,KCNN4,OPN3,NFE2L3,PGM1,PYGL,NPC2,EGFR,NMT2,CRISPLD2,SCG2,SLC2A6,NMI,NR4A3,CSGALNACT1,ERAP1,CLMN,CDK18,PKD2,PER3,FZD5,MAP3K5,L1CAM |
| 4.612e-13 | -28.41 | VECCHI_GASTRIC_CANCER_EARLY_UP | MSigDB lists | VECCHI_GASTRIC_CANCER_EARLY_UP | 388 | 111 | 17758 | 2588 |
ILDR1,KLK10,IL15RA,DLGAP5,S100A11,FOXM1,PTTG1,NDC80,SOD2,DHX8,NUF2,LACTB2,CCNB1,COMMD5,AIFM2,NUP62CL,BARD1,TMPRSS4,CENPN,FANCI,CCNA2,UBE2T,KIF14,CDH3,TACSTD2,SLC39A10,RASGEF1A,TUBA4A,CKS2,TMEM68,CENPA,HN1L,FIGNL1,PBK,CDC20,TFAP2C,KLK6,NUSAP1,CDCA2,F12,ANLN,CDK1,GINS4,ANKRD10,TRIM47,ABHD12,HOXA9,ZNF367,OVOL1,KLF5,MRPS28,PIEZO1,HSPB1,E2F8,GRN,IER5L,MZT1,DEPDC1,MACC1,CKAP2,CTSB,RACGAP1,GDF15,GPSM2,SAC3D1,IL17RB,TOP2A,E2F7,SPP1,SPIN4,KCNN4,MCF2L,RANBP1,PRC1,TFAP2A,CD9,NEK2,CKS1B,BUB1,CPLX1,FAR2,GAD1,S100A6,SMC4,HMMR,WDR72,ZWINT,MFI2,KIF20A,IFITM3,ASPM,MYEOV,MYBL2,WHSC1,FAM133B,COL7A1,GGH,SCRIB,POLD3,CDCA5,TMC5,PGRMC1,SERPINB5,AURKA,KLK7,HMGA1,NCAPG2,UBE2C,CCNB2,IFI6,MELK |
| 4.708e-13 | -28.38 | GNF2_CCNA2 | MSigDB lists | GNF2_CCNA2 | 67 | 35 | 17758 | 2588 |
DLGAP5,HJURP,FOXM1,NDC80,CDCA3,CDCA8,RACGAP1,FANCI,TOP2A,PCNA,CCNA2,KIF14,PRC1,CKS1B,SMC4,CKS2,PLK1,HMMR,CENPA,ZWINT,KIF20A,ASPM,CDC20,NUSAP1,AURKB,KIF11,CDK1,PRIM1,AURKA,CENPE,UBE2C,CCNB2,ESPL1,E2F8,MELK |
| 4.928e-13 | -28.34 | prostate | COSMIC cancer mutations | prostate | 14584 | 2246 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,DGAT2,OSCP1,GDF11,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,SYP,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,FAM102A,IGFBP2,CASD1,ACBD5,TACC1,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,ARFGEF1,NDRG2,F11R,MGAT5B,SLC9A3R2,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,SEMA3A,CCNB2,CDAN1,USP43,TMX4,RHPN2,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,HIPK3,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,ATP2C2,FAM78A,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,TRIQK,FZD7,ACAD10,CCDC149,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,PLD2,EFNB1,FGF19,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,TTPA,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,VARS2,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,WWTR1,PDXK,RGS14,ARNT,NKX3-1,TNRC6C,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,CYBRD1,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,MFAP3L,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,RUSC2,DAP,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,SLC45A3,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,BANK1,TWSG1,ZNF214,TMC5,NETO2,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,IL31RA,AOX1,STEAP2,IQCD,TFG,XKR8,LOC81691,TMEM68,SNTB2,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MMD,ZNF84,MICB,AMER1,FAM133B,KDM3A,RASA1,FAS,PRKAG2,NAB2,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,APLP2,DOK4,FICD,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,SLC16A14,ARL4C,GPR180,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,OSGIN1,PCCB,CASK,SHMT1,MPP1,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,NKAIN3,LRRC6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ASCL5,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KHNYN,FRYL,SMO,RPN2,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,CCDC24,CDS2,SORT1,FRMD6,JKAMP,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,RAB3B,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,L1CAM,SNPH,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,ARF4,PLCG1,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,MEGF8,ATP5H,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,ZMYM1,KANK3,DGKG,MYLIP,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,CLMN,CBX5,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,ST5,CDH1,SH3BP1,XYLT2,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,COL6A2,PFKFB2,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,IFT27,CTNNBIP1,ZFX,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,PLEKHA6,BTNL9,RGMB,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,SYTL2,TTC21B,PDGFA,WDR44,PPME1,ESPN,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,IL22RA1,VPS26A,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,P2RX4,HES1,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,TSPAN18,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,SIVA1,CTTN,SP5,STK35,LAMP3,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,RBM43,CAPN1,NR2C2,PPP1R12A,PYROXD2,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,DRD1,LMO7,CCNE2,HDAC11,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,WEE1,ARHGAP42,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,SLC37A1,CALCRL,PLS1,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,CDIPT,PIGL,PCNA,CNTRL,DDHD2,DUSP10,TLN2,MYBL1,S100A13,ZNF462,CD55,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,CCDC92,SLC35B4,ABCD1,KLF9,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,CLIP4,PKD2,ACADM,SAT2,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,AURKB,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,CEP70,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,ATP9A,CCNJL,CYB561,SEPP1,SPR,LGALS3BP,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,CASP3,LTBP1,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,MIIP,PSMC1,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,ZSWIM5,IL15,PSME2,SLC2A8,GMPR,MORC4,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,MAP3K6,PEX2,VSIG10,PLXND1,AKNA,SGOL1,LIFR,CBX4,ANXA3,POC1B,LRP4,AES,NOTUM,POMGNT1,ZNF212,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 6.021e-13 | -28.14 | regulation of protein kinase activity | biological process | GO:0045859 | 829 | 200 | 16441 | 2455 |
CCNC,CASP3,TXN,IBTK,DNAJC3,CAMKK1,EPHA4,NRG2,PSME1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,SHC3,RGS3,PSMC2,PIK3CA,DLG1,DUSP10,RASGRP1,PLK1,NEK4,SOD1,PRKAR2B,CDK1,PLCG1,CAMK2N2,GPRC5B,MADD,NOD2,MAP3K11,CAB39,HSPB1,PSMC1,GAB1,CDKN1C,UBASH3B,RASA2,PRKAA1,PSMD7,CALM3,DUSP5,BMP2,TFAP4,RB1,RAC2,IGF1R,CYR61,FBXO7,PAK2,MAP3K9,SORL1,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,SOCS5,MMD,MAPKAPK3,CALM1,STRADB,PDE5A,EPHA1,ILK,PSMA4,EGFR,RASA1,CDK5R1,MAPKAPK2,TSC1,PRKAG2,INSR,CSF1,STK39,EFNA1,MAP3K5,JAK3,DRD1,CCNE2,SPRED1,AVPI1,NF2,IQGAP1,PSME2,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,FLT3,EMP2,STIL,PDGFA,CCND1,APLP2,CCNA2,RALB,KIF14,CDKN1B,DAB2IP,RASGEF1A,CDKN2D,F2R,HSPA2,DVL2,FRS3,CHP1,CKS2,MAP3K3,SIRT1,PSRC1,RIPK2,AKT1,FZD4,PKMYT1,DUSP4,CD40,CDC25C,MAP3K6,SOCS3,IRS2,FYN,PTPRJ,CCNB3,JAK1,STK26,STK38,CORO1C,PSMD3,WWTR1,KIAA1804,SLC27A1,EFNA5,NRG1,SPTBN5,RGS14,PRKAR1A,PINK1,TAOK2,NKX3-1,TAB3,TRAF2,SDC4,PSMD10,HERC5,TGFBR1,PKN1,TRIB2,GSTP1,FGF19,DIRAS3,PDCD10,ADORA1,IRAK1,PTEN,BMP7,BAX,CKS1B,H2AFY,MAPK11,HEXIM2,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,DUSP1,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,GRIN1,RGCC,MAPK8IP1,CDK5RAP1,FGFR2,FGF18,RAP2C,ARRB1,PPP2R3C,GRIN2D,PKD2,CENPE,FZD5,CD81,UBE2C,HIPK3,PKIA |
| 6.186e-13 | -28.11 | regulation of programmed cell death | biological process | GO:0043067 | 1414 | 307 | 16441 | 2455 |
ACVR1,TRIM24,GRIK2,TSC22D3,FAM129B,DNAJC3,RET,XIAP,GATA3,PSME1,CAMK1D,SEPT4,BARD1,CARD10,TP73,DAPK2,PAK6,PSMD1,CTGF,ALDH1A3,IL31RA,PIK3CA,DNM2,PPP1CA,TIAM1,ANKRD9,NEK4,ACVR1C,CASP9,BNIP3L,AURKB,SAV1,SLC25A5,POR,ARF4,ABR,SLC25A4,DNM1L,PLK2,TBX1,PPP2R4,NOD2,MAP3K11,HDAC1,UNC5B,HSPB1,TRAF5,FGD1,ITGA6,SOX9,PRKAA1,SLC25A27,NOTCH2,MERTK,LMNA,MECOM,TFAP4,CALR,CYR61,MSH2,DAPK1,MAP3K9,TNFRSF12A,MYDGF,MAPK7,ANO6,FHL2,ILK,PSMA4,FBXO10,RHOB,RASA1,FAS,STK17A,HTT,SEMA4D,AURKA,NR4A2,STK39,GDF11,MAP3K5,RPS6KA3,XDH,DMPK,NQO1,THRA,INPP5D,RPS6KA1,CAST,BCL2L1,CD274,EGR3,AIFM2,FLT3,SP100,CDKN1B,DAB2IP,LGMN,CDKN2D,TMBIM1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CBL,IRS2,FYN,CDK19,NGFRAP1,STK26,WFS1,AXL,STAT1,NRG1,AREL1,ARHGEF3,HSP90B1,TAOK2,NKX3-1,TRAF2,BIK,PDIA3,NES,ETS1,GSTP1,BEX2,ICAM1,SIX4,PDCD10,IRAK1,CTSC,PTEN,MCF2L,CST3,SGK3,BAX,PLEKHF1,TMBIM6,ERBB3,CITED2,MAP3K7,RAG1,ITM2C,SPRY2,OSGIN1,RAPGEF2,PIK3R1,GRIN1,PIM3,GPLD1,BTG1,KIAA0141,FGFR2,PRDX3,NR4A3,ITGAV,GPER1,OSR1,MELK,CASP3,TRIM2,AGRN,SUDS3,HDAC6,ERP29,EPCAM,RPS6KA2,CTNNB1,P4HB,IL6ST,SIVA1,PSMC2,MITF,TNFRSF18,ARNT2,CTTN,SLC39A10,CYP1B1,PLK1,SOD1,KCNIP3,ITCH,PRKRA,STK17B,CDK1,VCP,OPTN,MDK,MADD,KLF11,PSMC1,PRKAA2,BMF,LGALS3,PSMD7,PHLPP1,ADAMTSL4,BMP2,IGF1R,TIMP1,PAK2,PRKCI,FNIP1,PIM1,WNT3A,PSMA5,OXR1,STRADB,SCRIB,IFIT3,BCL2L13,EGFR,CDK5R1,G2E3,NFKBIA,JAK3,IFI6,RARG,PSME2,TP53,SOD2,P2RX7,ERBB2,COL18A1,STIL,PHLDA1,BCAP31,ARHGEF16,IER3,SRPX,KIF14,PLCG2,SMO,BCL6,TWIST1,STEAP3,APIP,EGLN3,F2R,CTH,PPIF,SIRT1,BAG4,AKT1,FIGNL1,GLO1,CD40,MAP3K6,CASP4,SOCS3,PTGS2,BHLHB9,PSMD3,TLE1,IRF7,ARHGAP4,LIFR,CBX4,ZC3HC1,FAM134B,BIN1,GCLM,PINK1,CPEB4,ARHGEF11,DAP,CTSB,ARHGEF7,SERPINB9,PSMD10,SELL,GDF15,AES,TGFBR1,TOP2A,CARD8,ADORA1,BMP7,TFAP2A,SGK1,BUB1,KANK2,FAIM,DUSP1,RHOA,ADAM17,HMGN5,WNT10B,PSMB4,PLAUR,GCLC,RGCC,TRIM35,PELI3,BCAR1,MAPK8IP1,BCL10,CASP7,SCG2,DHRS2,E2F1,ARRB1,SOX8,ARHGEF9,HIPK3,ARHGEF4,NGEF |
| 6.580e-13 | -28.05 | anatomical structure development | biological process | GO:0048856 | 4662 | 845 | 16441 | 2455 |
DOC2A,HECA,ADD1,AK7,RET,MCOLN3,HEXB,CACNA2D2,CCNO,NRG2,IL18,KIF26A,GRM5,TP73,NPM2,CDKN2C,CALM2,WEE1,PSMD1,TGFBR3,PAQR5,ALDH1A3,DNM2,CLDN4,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,TIPARP,DNAAF3,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,GINS4,LCP1,ABR,PGF,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,MYLK,HDAC1,TMOD2,ITPKA,ARF6,E2F8,GAB1,HOXC13,SCN5A,TMTC3,ITGA6,SOX9,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,RAC2,FRY,MEGF8,FLRT3,ZIC5,NEK2,USP1,MYDGF,NCAM1,DGKG,MYLIP,TTLL1,PAQR7,REC8,UFD1L,SALL4,SHARPIN,FHL2,CALCRL,KIF20B,NPHP3,MEST,ILK,DPYSL4,PSMA4,GNA11,RHOB,PTPRF,NCOA3,ETS2,HTT,TIMM8A,SEMA4D,DGAT2,CLMN,AURKA,B4GAT1,GDF11,CFAP20,DRP2,NDE1,ARPC2,TRPC3,RPS6KA3,CSRP2,XDH,ADAMTS16,EGLN1,MTM1,PAPSS2,GRHL2,LFNG,WDTC1,C5orf30,PKP2,PRKACA,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,MYT1,SNX10,ETV4,SSH3,CAMSAP3,COL6A2,LGALS8,FZD4,SAT1,HTATIP2,TANC1,EBF2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,AXL,CORO1C,WFS1,SIPA1L1,WWTR1,PNPLA6,TRABD2A,RGS14,ARNT,MAPK12,TTC8,CTHRC1,TNRC6C,NKX3-1,FARP1,MAN1A2,SDC4,CCM2,BIK,FLOT1,CTSZ,PKN1,PLPPR4,ETS1,GSTP1,HOXB2,SRPX2,ICAM1,SGPL1,NEO1,CTNNBIP1,CAPN2,ANK1,PDCD10,IGSF9,ITGB8,KNDC1,GPC3,CST3,BAX,ADAM15,TMBIM6,WWP1,MAPK11,RAG1,SGCB,ITM2C,S100A6,POU6F1,ADAMTS2,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,RAB3IP,CRISPLD2,ABLIM2,TXK,CNTNAP1,PITX2,PROM1,ACVRL1,DBI,NR4A3,ITGAV,FHL1,OSR1,USF2,SHOX2,FOXA1,MYL9,EPAS1,AGRN,CUL4B,EPHA4,SUDS3,ARFGEF1,PHOSPHO1,NDRG2,F11R,PDGFB,SDC1,SPTB,SLC9A3R2,PLS3,TFAP2E,RPS6KA2,PCNA,CTNNB1,NPNT,SHC3,IL6ST,MITF,PAPSS1,PSMC2,ELF5,TMEM143,DUSP10,NTN4,NEB,THRB,MARK1,CELSR2,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CLCN2,CDK1,RHEB,DZIP1L,DPYSL3,IRX3,HS6ST1,AGPAT2,MAP2,HOXA9,MAFF,MYL12B,RUNX2,USH1C,LGALS3,RASA2,PSMD7,RACGAP1,CNTNAP2,NCKAP1,DHRS3,PGAP1,IL18R1,SSX2IP,BMP2,TNS3,RB1,DAZAP1,VASP,TIMP1,IGF1R,GATA2,KIF13B,FRAS1,PAK2,NTN1,WNT3A,ALDH3A2,PSMA5,CYP26B1,DPYSL5,PCDH1,RGMB,STRADB,TCF7,SCRIB,EIF2AK1,UNC45B,G2E3,PRX,SMN1,CDK5R1,FOXD2,MAPKAPK2,MOSPD3,FA2H,COL13A1,PVRL2,MFSD2A,PHLPP2,ITGA7,CSF1,PRPS2,AKIP1,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,STIL,SDF4,PER2,IER3,TTC21B,PDGFA,TACC2,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,GYS1,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,TIMP2,MBP,AKT1,S100A4,CDC20,PTGER4,MYL12A,DAG1,PTGS2,DUOX1,RTN4RL1,PTPRJ,PAFAH1B3,PTK7,PSMD3,EFNA5,RPL22,LTA4H,POMGNT2,CTDSP1,BIN1,COL9A3,PACSIN2,DYRK3,CDH22,ADGRG1,CTSB,PSMD10,GDF15,JAG2,CRABP2,FZD6,PPP2R3A,NRP2,GBX2,ZDHHC21,CD109,FOXP2,CDK16,UBE2J1,TFAP2A,SGK1,HMGCL,SYK,CAMK2G,FAM134C,TLE6,GCNT1,DUSP1,HES1,RHOA,PSMB4,CRIP2,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BBS2,PRDX4,BCL10,CNOT2,FAT4,SCG2,TWSG1,FGF18,PGRMC1,E2F1,PKD2,PPP2R3C,CFAP74,GAA,ACVR1,LGR4,SSH1,HSPG2,TMEM41B,CUL1,GATA3,PSME1,CAMK1D,PLXNA1,CCNB1,VASH1,SEPT4,FAM101B,NCS1,PICK1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,POLL,PIK3CA,TACSTD2,RCAN3,ZBTB18,PACSIN1,SGCE,CASP9,LDB2,CCNF,SAV1,ZFAND5,ULK2,ARHGEF26,SFXN1,HLF,AREG,TBX1,PLK2,PTER,NKD1,LRIG1,BMP1,DHTKD1,SERPINI1,TANC2,UNC5B,F2RL1,LZTS1,FGD1,SEMA6B,KLF2,INPPL1,CDKN1C,SLC25A27,NOTCH2,SLC1A3,HERC6,APBA1,TNFRSF19,KIAA1161,MECOM,MESDC2,CALR,ITGA3,CYR61,BHLHE41,PRKG1,MSH2,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,TMED2,RIMS2,IGSF3,DNAI1,EPB41L5,KLK5,MMD,B9D2,CEP89,CALM1,AMER1,DCHS1,ANO6,WHSC1,VEZT,EPHA1,KDM3A,ANTXR1,NFIB,STX3,RASA1,FAS,MMP15,WDR19,MATN2,NAB2,FAM83D,PCDH19,KLK7,NR4A2,EFNA1,HOOK1,EHD1,IRF1,SPRED1,FOXO6,TCF25,TCTN2,ST14,THRA,CAST,RPS6KA1,IQGAP1,NDRG1,IRX4,BCL2L1,EGR3,DDR1,FLT3,EPM2A,NOV,APLP2,CCNA2,DOK4,CDKN1B,CNNM4,DAB2IP,EPHB4,PDE4D,FLOT2,SEMA3B,FOXJ2,DMTN,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CEP162,CMTM7,EPHA10,FYN,JAK1,STAT1,RAB29,NRG1,KLF5,CBX7,COBL,ATMIN,PRKAR1A,WASF3,JRKL,HAPLN3,CENPI,PBX3,NES,SEPP1,SPR,FGF19,EFNB1,TEAD3,ADGRB2,SIX4,SCML1,RND1,E2F7,OXCT1,MGAT1,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,ERCC2,TAGLN2,MAP3K7,CITED2,TTPA,GFI1,SPRY2,MSH6,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,VAMP3,DIAPH2,C1GALT1C1,YES1,FOS,GPLD1,CDK5RAP1,RGS9,TIMP3,CTNS,DGCR2,FGFR2,PRDX3,TBX18,RYK,ERAP1,SERPINB5,GRIN2D,LRRK1,GPER1,FZD5,WDR62,ARSB,NCAPG2,SLC25A38,MELK,RGMA,JARID2,EXPH5,EMX1,CASP3,UGT8,UBE2Q1,MPP5,PLAC1,CACNB4,DNER,TMC1,EPCAM,LRRC6,GRHL1,CDKL5,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,ASH2L,RP2,CTTN,MYH14,ARNT2,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,SOD1,ASXL1,FOPNL,RNF165,EDNRA,CXXC4,MDK,GPRC5B,HPSE,TDRD7,TRIM45,NRGN,APBA2,PPP2R5D,PSMC1,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,TEC,DUSP5,SPP1,CA2,LRRN2,FAM20C,OCRL,COL6A1,PRKCI,FNIP1,NPTN,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,HMG20B,C3orf58,RANBP9,EGFR,SOX13,FECH,GNAS,BCAR3,ONECUT1,TSC1,INSR,PLPP3,TMEM30A,ALPK3,PITPNA,EGFL7,SHROOM2,JAK3,RARG,DRD1,KLF7,PAX6,IL15,PSME2,HDAC11,COL18A1,MRAS,ZMYND10,OSR2,MICALL2,PHLDA1,EXT2,SS18,ARTN,SETDB2,FRYL,KIF14,SMO,DIXDC1,TWIST1,ECE1,NFKB2,LOXL1,F2R,HSPA2,FRS3,MAP3K3,PTPRU,OSTM1,IGSF8,GLO1,DUSP4,ARHGAP35,SOCS3,HSF4,ALDH5A1,BFSP1,BHLHB9,STAT6,PEX2,SECTM1,TLE1,PTBP3,OVOL1,SPTBN5,PLXND1,LIFR,ANXA3,SORT1,ARHGEF11,POC1B,FRMD6,ARHGEF7,CIT,LRP4,TGFBR1,COL4A5,AES,ITGA2B,HDAC9,KIF5B,TOP2A,MDM1,ADRBK1,ADORA1,LLGL2,BMP7,MYCL,TOX2,KIAA0319,ACTA2,TRIM3,RPGR,MYO5A,ADAM17,WNT10B,CFAP46,NR4A1,ASPM,RC3H2,TTC7A,RUNX3,FAM73B,FOXL1,SPAG1,MAP1B,ARHGAP24,LEMD2,CD8A,SWAP70,PRCP,DHRS2,CTSV,SPINT2,RAP2C,CSGALNACT1,ARRB1,HOXB13,CEP41,PLOD3,SOX8,ZMIZ1,L1CAM,AHR,NGEF |
| 6.968e-13 | -27.99 | CHICAS_RB1_TARGETS_SENESCENT | MSigDB lists | CHICAS_RB1_TARGETS_SENESCENT | 539 | 141 | 17758 | 2588 |
FAF2,VASH1,FAM101B,SLC20A1,CHST2,FANCI,WEE1,CPNE2,BTG3,PCNA,UBE2T,IL6ST,PAQR5,ALDH1A3,TUBG1,TRPC1,RGS5,APOBEC3G,ANKRD9,ERAP2,SPATA18,ACBD3,CCBL2,LDB2,PRIM1,EDNRA,DPYSL3,PI4K2B,CAMK2N2,HPSE,AREG,ZNF367,FAM114A1,LRIG1,NFKBIZ,GLCCI1,NRGN,FRMD4A,PSIP1,DUSP5,CALR,SPIN4,RANBP1,MSH2,USP1,NUP85,SNX7,CYP26B1,DDB2,MMD,KIAA1841,OXR1,BTN3A2,IFIT3,STEAP1,CYB5A,SLCO4A1,TMEM54,DCK,PRPS2,RAB31,DGAT2,OSMR,DONSON,NDE1,CBX5,IFI6,TMEM173,CCNE2,CCDC109B,PSME2,CD82,SOD2,KCTD12,IL27RA,CD274,EGR3,SLC7A2,PHLDA1,EMP2,APLP2,SP100,RNASEH2A,RAB27B,LRP11,CTH,COL6A2,RIPK2,CYB5R2,SLC39A8,NUSAP1,ATP1B1,RAB38,PTGS2,PDLIM3,ACYP1,WWTR1,NRG1,ST3GAL1,SLC27A3,KDELC2,GLIS3,GCLM,PCOLCE,ENO2,TRIB2,NUCB2,LGALS3BP,SAC3D1,SLC25A36,DTX3L,DIRAS3,ADD3,MLPH,OXCT1,FUT8,H2AFY,ALDH7A1,KANK2,MSH6,FAH,TGIF1,PLSCR1,GUSB,STMN3,COL7A1,POLD3,BBS2,HLA-B,SERPINA1,SLC25A40,CDCA7L,NETO2,ACADM,GEM,NCAPG2,CYBRD1,ACOT7,MELK,DCBLD1,JARID2 |
| 7.678e-13 | -27.90 | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | MSigDB lists | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | 1587 | 331 | 17758 | 2588 |
FAM171B,PPP4R4,KLK10,TTC39B,TMEM41B,MCOLN3,FBXO2,GATA3,SPSB1,SESN3,TGFBR3,ARHGAP42,RGS12,ZNF823,SNX16,SEMA3G,RNF26,CPE,VPS11,CDYL,BNIP3L,CDA,MTRF1L,KIF13A,CYP4F3,RAB2B,CARHSP1,RBM47,LRIG1,BMP1,AGFG2,SERPINI1,TMOD2,RNASEL,TANC2,E2F8,RECQL,MRC2,NUAK1,ADO,MTL5,RAB23,KIF23,ISYNA1,SLC1A3,PSIP1,TSPAN7,PRRG4,MARCH8,PAIP2B,NEK2,TMEM51,DAPK1,FBXL14,MAP3K9,ALPK1,MAST4,C9orf72,SYTL3,TTLL1,RIMS2,EEF1D,MCCC2,EPHX1,DDB2,KLK5,KIF20A,TBC1D8B,CEP89,STAT4,TMEM133,KCTD20,SRSF5,KDM3A,TP53INP2,GLT8D2,C11orf45,NT5C2,CACHD1,FAM64A,C1orf21,WDR19,FAM83D,OSMR,CLMN,CDK18,KLK7,STK39,EFNA1,PER3,ZNF502,HOOK1,IFIH1,EGLN1,WDR63,PAPSS2,DLGAP5,TCTN2,TUBB4B,LFNG,CD82,CERCAM,WDTC1,ETNK1,RGS20,TESK2,NUF2,SNN,TMEM19,PRKACA,DDR1,TMPRSS4,ART5,ZNF385B,CCND1,CYHR1,ZNF75D,DAB2IP,IFIT1,PDE4D,ARL4D,TSPAN1,SULT2B1,PSRC1,APOBEC3D,NRBF2,SYNE2,SLC11A2,NUSAP1,BCL7B,ZNF618,GIGYF1,GABARAPL1,ALDH3B1,CBX7,PLSCR4,RBM24,CKAP2,HABP4,CDCA3,FLOT1,ZNF219,DTX3L,CXCL16,ADD3,TMEM87B,KCNK5,DRAM1,ATP8B1,ERBB3,PARP9,PDGFC,PIK3R1,PLEKHA7,FBXO9,DIAPH2,LRRC1,RAB3IP,KIF11,CRTC2,TIMP3,RPL12,KIAA0141,ACADSB,FGFR2,SLC35B3,PLA2G15,SERPINB5,CENPE,CYBRD1,CXorf56,EXPH5,BCAM,ST13,CRYM,CPT2,EPHA4,MCCC1,NDC80,PLAC1,KIF2C,TP53I11,HDAC6,DENND2D,ZFYVE16,CDKL5,ARHGEF37,METTL7A,CNTRL,ARL1,POF1B,NTN4,RP2,PXMP4,PLK1,CXXC5,CELSR2,ITCH,NFE2L1,RGAG1,CCBL2,TCN2,HPSE,KCNK1,MAP2,WIPI1,DOLPP1,PIEZO1,POMT1,EPB41L4A,GLCCI1,PCSK5,BVES,DNAJB2,CNTNAP2,PHLPP1,BMP2,ZNF432,TNS3,CA2,CES2,IGF1R,KIF13B,EXOC8,FNIP1,RFX5,C10orf54,LRIF1,GAD1,MPHOSPH9,HP1BP3,CYP26B1,BTN3A2,RNF113A,ANKRD29,FECH,XKRX,MOSPD3,EPN3,INSR,UAP1,H1F0,CSF1,NFKBIA,PAPD5,PLD1,CCNB2,APOL2,RARG,RNF146,LZTFL1,KCNAB3,SOD2,ZNF28,EMP2,SYTL2,C1orf116,PDGFA,KIF14,BCL6,STEAP3,ZBTB49,F2R,CTDSP2,CTH,S100A4,SERTAD3,TMTC2,KCTD2,CDC25C,C3orf33,STK38,STAT6,OVOL1,MAOA,EFNA5,REEP4,MAD2L1BP,ZNF701,CMTM4,FAM134B,PINK1,CPEB4,KLHL13,TSPAN15,POC1B,SCD5,ARMC7,MCTP2,GNAL,BLVRB,MIER3,GDF15,HMGN3,COL4A5,NKRF,CRABP2,H1FX,HDAC9,ALPP,LLGL2,FAM63A,TFAP2A,BRD7,ACTA2,MXD3,KLF9,C12orf75,RPGR,CAMK2G,FAM134C,LRRC24,HMGN5,ASPM,LRRC66,MBNL3,PRICKLE1,BBS2,USP6,KLHL2,ARHGAP24,FAT4,TRIM69,NIPSNAP3A,FGF18,TADA2B,CLIP4,UACA,ZMIZ1,ZNF596,GOLGB1 |
| 8.692e-13 | -27.77 | stomach-carcinoma-adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-adenocarcinoma | 15944 | 2415 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,ZNF618,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,GPR161,TRAK2,PIGC,GFPT1,GCC2,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,NXPH4,CTSA,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,CAMK2G,IGDCC4,MLEC,NR3C1,AMFR,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,SMYD5,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,TRIP10,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,DAB2IP,PHKA2,NR2C1,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,IL22RA1,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,VASN,TPST1,DAPK1,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,CAPN12,REPS2,GPR107,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,RELL1,E2F8,GAB1,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,LMAN2L,DDHD2,DUSP10,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,HOXB13,GEM,LRRC57 |
| 9.659e-13 | -27.67 | CHICAS_RB1_TARGETS_CONFLUENT | MSigDB lists | CHICAS_RB1_TARGETS_CONFLUENT | 531 | 139 | 17758 | 2588 |
MYL9,FAM171B,TXN,ADD1,EPHA4,PDGFRL,FAM46C,CARD10,SIPA1L2,ZYX,METTL7A,OSBPL3,ALDH1A3,CAPG,NTN4,ARNT2,SCARA3,ANO4,CPE,SMAGP,OLFML2A,CXXC5,SNTB2,LOXL2,ROR1,TP53I3,OPTN,PRIM1,DPYSL3,MDK,CARHSP1,TRAM2,MPRIP,GPRC5B,MYLK,PRKCDBP,HSPB1,F2RL1,CD99,ITGA6,NOTCH2,DHRS3,TNFRSF19,FBLN1,ANO1,LMNA,MECOM,TNS3,FRY,COL6A1,OPN3,C10orf54,MOXD1,SNX7,FAM69A,PQLC3,PRSS23,RGMB,FHL2,PDE5A,MEST,NMT2,CYB5A,STK17A,PRKAG2,MATN2,SH3BP4,FGD6,LTBP2,PLIN3,SHROOM2,KLF7,EHD1,CCNE2,LMO7,CCDC109B,TUBB4B,XYLT1,NUF2,FAM198B,SNN,SYTL2,APOBEC3B,TWIST1,STEAP3,LOXL1,GPX4,TMEM200B,TMTC1,TIMP2,COL6A2,S100A4,UTRN,TMTC2,ZNF469,NFIX,ABHD12,CORO1C,AXL,NR3C2,KDELC2,CTHRC1,PCOLCE,FARP1,IGFBP6,BLVRB,SDC4,FLOT1,ARL4C,NES,DTX3L,RNF128,CD9,ATP8B1,ACTA2,H2AFY,C12orf75,S100A6,PARP9,NFE2L3,ADAMTS2,RAB3B,IFITM3,DENND1B,EMP3,STMN3,PRICKLE1,KIF11,FOXL1,MAP1B,CNTNAP1,NIPSNAP3A,NMI,ARRB1,UACA,HMGA1,CD81,ACOT7,MELK |
| 9.797e-13 | -27.65 | phosphotransferase activity, alcohol group as acceptor | molecular function | GO:0016773 | 705 | 175 | 16491 | 2452 |
LTBP1,NMRK1,TNK1,ACVR1,TRIM24,CAMKK1,RET,EPHA4,PDGFRL,CAMK1D,CCNB1,DAPK2,PAK6,WEE1,TGFBR3,RPS6KA2,CDKL5,PASK,PAPSS1,PIK3CA,PIK3CD,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,AURKB,ROR1,STK17B,CDK1,ADRBK2,ULK2,PI4K2B,FASTKD1,LIMK1,PLK2,MYLK,MAP3K11,MAPK13,PIK3C2B,RNASEL,ITPKA,PRKAA2,CDK17,LMTK3,NUAK1,PRKAA1,DGKQ,SOX9,ADCK5,TEC,MERTK,BMP2K,IGF1R,FAM20C,PFKL,PAK2,DAPK1,MAP3K9,ADCK2,PRKG1,PRKCI,NEK2,NPTN,ALPK1,PIM1,PIKFYVE,MAPK7,DGKG,MAST4,PHKG2,MMD,MAPKAPK3,TESK1,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,PKM,ILK,PDIK1L,EGFR,CDK5R1,STK17A,DGKH,MAPKAPK2,NT5C2,INSR,PRKAG2,CSNK1G1,ALPK3,AURKA,STK39,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,PAPSS2,RPS6KA1,ETNK1,DGKA,TESK2,ERBB2,MAPK4,GRK6,PRKACA,DDR1,FLT3,CDK14,CCND1,PLK4,EPHB4,PHKA2,MAP3K3,AKT1,RIPK2,RFK,PFKFB2,PANK1,PRKCQ,PKMYT1,XRCC6BP1,MAP3K6,EPHA10,FYN,JAK1,CDK19,STK26,PTK7,AXL,STK38,KIAA1804,MLKL,PDXK,MAPK12,GALK1,TAOK2,PINK1,DYRK3,CIT,GNE,TGFBR1,PKN1,TRIB2,NRP2,IRAK1,ADRBK1,CDK16,FAM20B,SGK3,SGK1,MAPK11,BUB1,ERCC2,ERBB3,MAP3K7,SYK,CAMK2G,CASK,NADK2,YES1,PIM3,DGKE,TXK,ACVRL1,FGFR2,RYK,PGM2L1,LRRK1,HIPK3,MELK |
| 1.229e-12 | -27.42 | FEVR_CTNNB1_TARGETS_UP | MSigDB lists | FEVR_CTNNB1_TARGETS_UP | 646 | 161 | 17758 | 2588 |
CASP3,ACACB,TTC39B,GNPDA1,ATP8A1,TAP1,F11R,TGOLN2,SLC20A1,CHST2,TYMP,ZYX,CTGF,ELMO2,PPP1R16A,KLF3,RAB20,CRY2,CTTN,PTPRE,CPE,IL10RB,TRIM8,KIFC2,USP18,CASP9,KDELR3,ERP44,KLK6,MCFD2,CLCN2,STK17B,POR,ABR,SEC14L2,OPTN,TMEM164,HLF,FAM114A1,UNC5B,ITPKA,MAFF,PCSK5,LGALS3,GGA1,HLA-E,DNAJB2,RAB6A,LMNA,SPP1,AIM1L,ITGA3,TNFRSF12A,CACNA1D,PIM1,KLK5,CORO2A,EIF2AK1,EPHA1,IFIT3,GNA11,STX3,MMP15,SLC6A6,FAAH,CGREF1,NAB2,DGAT2,CLMN,CDK18,EFNA1,TMEM120A,SERPINB1,KLF7,IRF1,XDH,MTM1,CCDC109B,UGP2,GPR107,IL15,SLC2A8,ATP2C2,C5orf30,DGKA,IL13RA1,FAM78A,SYTL2,EPS8L2,CDS1,KHNYN,FABP6,PLCG2,SRR,BCL6,VAT1,GOT1,DLG3,EGLN3,SULT2B1,ERMP1,LGALS8,PFKFB2,SYNE2,CLSTN1,GLO1,SLC11A2,DOCK5,CASP4,SOCS3,GABARAPL1,WFS1,CORO1C,PLEKHG1,TRIOBP,STAT1,IRF7,CYP2U1,FAM134B,PRKAR1A,CDS2,JKAMP,DAP,CTSB,HAL,EPS8,FLOT1,NUCB2,NRP2,PARM1,SGPL1,CXCL16,ADRBK1,MLPH,IGSF9,KCNK5,RRBP1,ABCD1,GFI1,S100A6,OSGIN1,GCNT1,DUSP1,MOB4,P2RX4,OPLAH,GCLC,LITAF,CAPNS1,NPDC1,FOS,CD8A,DDAH1,SYT7,TMC5,ABCB1,SERPINB5,ARFGAP3,CMPK2,NDFIP1,OCLN |
| 1.231e-12 | -27.42 | cell morphogenesis | biological process | GO:0000902 | 1143 | 257 | 16441 | 2455 |
CFAP74,ADD1,SSH1,AK7,CCNO,GATA3,NRG2,PSME1,PLXNA1,FAM101B,CALM2,WEE1,PSMD1,TGFBR3,DNM2,PACSIN1,TIAM1,DNAAF3,SPEF2,CASP9,LOXL2,ARHGEF26,ULK2,PLCG1,LIMK1,TRAF3IP1,UNC5B,KLF2,SCN5A,SOX9,RAB23,SLC1A3,MERTK,RAC2,FRY,FLRT3,CACNA1D,NCAM1,TTLL1,DNAI1,EPB41L5,B9D2,CEP89,CALM1,KIF20B,EPHA1,ILK,NPHP3,ANTXR1,DPYSL4,NFIB,PSMA4,RASA1,RHOB,SEMA4D,MATN2,WDR19,FAM83D,AURKA,NR4A2,EFNA1,B4GAT1,ARPC2,CFAP20,TRPC3,RPS6KA3,EHD1,SPRED1,GRHL2,TCTN2,ST14,RPS6KA1,IQGAP1,C5orf30,DACT1,DAB2IP,EPHB4,DLG3,RASGEF1A,SNX10,ETV4,SEMA3B,COL6A2,FZD4,SLC11A2,PRKCQ,ALCAM,FZD7,CEP162,EPHA10,IRS2,FYN,JAK1,SHROOM3,SLC9A6,AXL,WWTR1,NRG1,COBL,ATMIN,TTC8,FARP1,FLOT1,NES,PLPPR4,SPR,EFNB1,FGF19,RND1,NEO1,ANK1,PTEN,ADAM15,ERBB3,S100A6,FARP2,RASGRF1,B3GNT2,ARHGEF28,FMN1,RAPGEF2,VAMP3,GRIN1,C1GALT1C1,RAB3IP,YES1,ABLIM2,CNTNAP1,FGFR2,NR4A3,RYK,GRIN2D,ITGAV,RGMA,MYL9,EMX1,CASP3,UGT8,AGRN,EPHA4,PDGFB,CACNB4,SPTB,RPS6KA2,CTNNB1,LRRC6,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,CTTN,RP2,MYH14,BTBD3,RASGRP1,ATL1,SOD1,CELSR2,FOPNL,RNF165,EZR,DZIP1L,DPYSL3,MAP2,MYL12B,PSMC1,BVES,RASA2,PSMD7,CALM3,DUSP5,SSX2IP,BMP2,RB1,VASP,IGF1R,LRRN2,OCRL,COL6A1,PAK2,NTN1,WNT3A,PSMA5,DPYSL5,RGMB,STRADB,SCRIB,RANBP9,CDK5R1,EGFR,ONECUT1,PITPNA,AKIP1,SEMA3A,SHROOM2,JAK3,KLF7,PSME2,COL18A1,P2RX7,ERBB2,RASGRP3,ZMYND10,MICALL2,STIL,PDGFA,TTC21B,SS18,ARTN,KIF14,FRYL,BCL6,SMO,FRS3,S100A4,DAG1,MYL12A,ARHGAP35,PSMD3,SPTBN5,EFNA5,PLXND1,LIFR,COL9A3,PACSIN2,ARHGEF11,ARHGEF7,POC1B,FRMD6,LRP4,PSMD10,COL4A5,TGFBR1,ITGA2B,NRP2,GBX2,KIF5B,BMP7,SGK1,RPGR,CAMK2G,HES1,RHOA,PSMB4,CFAP46,BBS2,SPAG1,MAP1B,SPINT2,FGF18,PGRMC1,PLOD3,CEP41,L1CAM,NGEF |
| 1.262e-12 | -27.40 | kinase activity | molecular function | GO:0016301 | 775 | 188 | 16491 | 2452 |
LTBP1,NMRK1,TNK1,ACVR1,TRIM24,AK7,CAMKK1,RET,EPHA4,PDGFRL,CAMK1D,CCNB1,DAPK2,PAK6,WEE1,TGFBR3,RPS6KA2,CDKL5,PASK,PAPSS1,DLG1,PIK3CA,PIK3CD,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,AURKB,ROR1,STK17B,CDK1,ADRBK2,ULK2,PI4K2B,FASTKD1,LIMK1,PLK2,MYLK,MAP3K11,MAPK13,PIK3C2B,RNASEL,ITPKA,PRKAA2,CDK17,LMTK3,NUAK1,PRKAA1,DGKQ,SOX9,ADCK5,TEC,MERTK,BMP2K,IGF1R,FAM20C,PFKL,PAK2,DAPK1,MAP3K9,ADCK2,PRKG1,PRKCI,NEK2,NPTN,ALPK1,PIM1,PIKFYVE,MAPK7,DGKG,MAST4,PHKG2,MMD,MAPKAPK3,ADCK3,TESK1,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,PKM,ILK,PDIK1L,EGFR,CDK5R1,STK17A,DGKH,MAPKAPK2,NT5C2,INSR,PRKAG2,DCK,CSNK1G1,PRPS2,MPP2,ALPK3,AURKA,STK39,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,PAPSS2,RPS6KA1,ETNK1,DGKA,TESK2,ERBB2,MAPK4,GRK6,PRKACA,FLT3,DDR1,CDK14,CCND1,PLK4,EPHB4,PHKA2,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,RIPK2,RFK,PFKFB2,PANK1,PRKCQ,PKMYT1,XRCC6BP1,MAP3K6,EPHA10,FYN,JAK1,CDK19,STK26,PTK7,AXL,STK38,KIAA1804,MLKL,PDXK,MAPK12,GALK1,TAOK2,PINK1,DYRK3,CIT,GNE,TGFBR1,PKN1,TRIB2,NRP2,IRAK1,ADRBK1,CDK16,FAM20B,SGK3,SGK1,MAPK11,BUB1,ERBB3,AK3,ERCC2,MAP3K7,SYK,CAMK2G,CASK,MPP1,NADK2,AK4,YES1,PIM3,DGKE,TXK,ACVRL1,FGFR2,RYK,PGM2L1,LRRK1,CMPK2,HIPK3,MELK |
| 1.288e-12 | -27.38 | PASINI_SUZ12_TARGETS_DN | MSigDB lists | PASINI_SUZ12_TARGETS_DN | 308 | 93 | 17758 | 2588 |
SLC25A24,SUZ12,PKP2,PDGFB,SDC1,PHLDA1,SPSB1,NCS1,IER3,ZYX,NPNT,DPYSL2,SMO,STEAP2,VAT1,ACSL4,CPE,TMBIM1,SP5,CYP1B1,SOAT1,TIMP2,AKT1,TMEM43,SH3BGRL,SERTAD4,LOXL2,DUSP4,CMTM7,IRS2,PDLIM3,PLK2,CORO1C,AXL,WWTR1,BMP1,EFNA5,RTN3,ANXA3,ARAP3,FARP1,SCOC,NUAK1,SERPINB9,ARL4C,HMGN3,COL4A5,DOCK11,TNFRSF19,ETS1,TTYH3,TMCC3,BMP2,CAPN2,ITGA3,CYR61,FLRT3,CALD1,UBE2J1,ACTA2,TNFRSF12A,TAGLN2,FAM84B,CITED2,S100A6,DUSP1,AMOTL2,PRSS23,AMFR,LPGAT1,PRICKLE1,EPHA1,CYFIP2,AIF1L,ILK,TCEAL8,STEAP1,MUM1L1,RHOB,FRMD4B,GNAS,PITX2,PROM1,PLOD2,RND3,CSNK1G1,CSF1,TMEM30A,RYK,ITGAV,PKIA,RPS6KA3,KLF7 |
| 1.327e-12 | -27.35 | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | MSigDB lists | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | 574 | 147 | 17758 | 2588 |
UNKL,HECA,EPAS1,VANGL1,EPHA4,TGOLN2,PLXNA1,FAM46C,PHF1,WEE1,BTG3,DPYSL2,DNM2,SNX16,NTN4,CRY2,ANKRD9,CELSR2,ITCH,PTGFRN,MFAP3L,HLF,CAMK2N2,KLF12,LIMK1,ZNF367,LRIG1,RAB11FIP1,MAP3K11,AGFG2,KPNA2,KLF11,SPRY4,GAB1,NR2C2,FGD1,FRMD4A,KIF23,SSX2IP,MARCH8,RB1,UBE2Q2,OCRL,BHLHE41,MAP3K9,SORL1,PANX2,CYP26B1,DPYSL5,ELK3,TBC1D8B,LPGAT1,OXR1,ANO6,KBTBD8,PLS1,TP53INP2,NCOA3,SERTAD2,CSNK1G1,PHLPP2,SFMBT1,YOD1,NR4A2,MAP3K5,NIPA1,RPS6KA3,IRF1,FAM45A,SLC2A4,GRHL2,TRIP10,RPS6KA1,THRA,MAPK4,BAHD1,ZFYVE9,CCND1,ENPP5,LHX6,TMEM64,ACSL4,RASGEF1A,EGLN3,MAP3K3,TIMP2,FOXJ2,TANC1,GIGYF1,ARHGAP35,RBL1,STK38,ZNF704,ZBTB6,PRR15,ABCA1,ARHGEF3,TAOK2,JRKL,ARHGEF11,FRMD6,HABP4,FAM134A,ARL4C,PBX3,EFNB1,NFAT5,DNAJB9,NRP2,VPS26A,M6PR,CEP97,RNF128,ITGB8,GNB5,PTEN,LYPD6,CALD1,FJX1,UBE2J1,TRIM3,FAM102A,KLF9,FAM134C,SMC4,P2RX4,PIK3R1,SYBU,EIF5A2,FURIN,PPARA,YES1,FNDC3A,USP6,TMEM50B,LDLRAP1,RAP2C,E2F1,NR4A3,NETO2,FAM117A,CLIP4,PKD2,OSR1,PKIA,FOXA1,RGMA |
| 1.427e-12 | -27.28 | ovary-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | ovary-carcinoma-endometrioid_carcinoma | 474 | 127 | 17775 | 2585 |
TNK1,ACVR1,NF2,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,FLT3,DDR1,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDH1,CDKL5,PIK3CA,PLK4,EPHB4,CDKN2D,SCYL3,STK35,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,IDH1,MAP3K6,ADRBK2,STK17B,ULK2,EPHA10,FYN,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MYLK,KIAA1804,MAP3K11,MAPK13,RNASEL,MLKL,MAPK12,PRKAA2,PINK1,DYRK3,TAOK2,CDK17,PRKAA1,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,RB1,IGF1R,IRAK1,ADRBK1,CDK16,PTEN,NEK2,MSH2,DAPK1,SGK3,PRKCI,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MAPK7,MAP3K7,SYK,PHKG2,CAMK2G,MSH6,CASK,ADCK3,TESK1,PIK3R1,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,EGFR,TXK,STK17A,GNAS,MAPKAPK2,INSR,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,RPS6KA3,MELK,DMPK |
| 1.598e-12 | -27.16 | regulation of cell death | biological process | GO:0010941 | 1498 | 320 | 16441 | 2455 |
TXN,ACVR1,TRIM24,GRIK2,TSC22D3,FAM129B,DNAJC3,RET,XIAP,GATA3,PSME1,CAMK1D,SEPT4,BARD1,CARD10,TP73,DAPK2,PAK6,PSMD1,CTGF,ALDH1A3,IL31RA,PIK3CA,DNM2,PPP1CA,TIAM1,ANKRD9,NEK4,ACVR1C,CASP9,BNIP3L,AURKB,SAV1,SLC25A5,POR,ARF4,ABR,SLC25A4,DNM1L,PLK2,TBX1,PPP2R4,NOD2,MAP3K11,HDAC1,UNC5B,HSPB1,TRAF5,FGD1,ITGA6,SOX9,PRKAA1,SLC25A27,NOTCH2,MERTK,LMNA,MECOM,TFAP4,CALR,CYR61,MSH2,DAPK1,MAP3K9,SORL1,TNFRSF12A,MYDGF,MAPK7,EEF1D,ANO6,FHL2,ELK1,ILK,PSMA4,FBXO10,RHOB,RASA1,FAS,STK17A,HTT,SEMA4D,AURKA,NR4A2,STK39,CABIN1,GDF11,MAP3K5,RPS6KA3,XDH,DMPK,NQO1,THRA,INPP5D,RPS6KA1,CAST,BCL2L1,CD274,EGR3,AIFM2,FLT3,NOV,SP100,CDKN1B,DAB2IP,LGMN,CDKN2D,TMBIM1,RIPK2,VPS4B,HTATIP2,PRKCQ,SLC11A2,CBL,IRS2,FYN,CDK19,NGFRAP1,STK26,WFS1,AXL,STAT1,NRG1,AREL1,ARHGEF3,HSP90B1,TAOK2,NKX3-1,TRAF2,BIK,PDIA3,NES,ETS1,GSTP1,BEX2,ICAM1,SIX4,PDCD10,IRAK1,CTSC,PTEN,MCF2L,CST3,SGK3,BAX,PLEKHF1,TMBIM6,ERBB3,CITED2,MAP3K7,RAG1,ITM2C,TTPA,SPRY2,OSGIN1,RAPGEF2,PIK3R1,GRIN1,PIM3,GPLD1,BTG1,KIAA0141,FGFR2,PRDX3,NR4A3,ITGAV,GPER1,OSR1,MELK,CASP3,TRIM2,AGRN,SUDS3,HDAC6,ERP29,EPCAM,RPS6KA2,CTNNB1,P4HB,IL6ST,SIVA1,PSMC2,MITF,TNFRSF18,ARNT2,CTTN,SLC39A10,CYP1B1,PLK1,SOD1,KCNIP3,ING1,ITCH,PRKRA,STK17B,CDK1,VCP,OPTN,MDK,MADD,KLF11,PSMC1,PRKAA2,BMF,LGALS3,PSMD7,PHLPP1,ADAMTSL4,BMP2,IGF1R,TIMP1,PAK2,PRKCI,FNIP1,PIM1,WNT3A,PSMA5,OXR1,STRADB,SCRIB,IFIT3,BCL2L13,EGFR,G2E3,CDK5R1,NFKBIA,JAK3,IFI6,RARG,SLC25A24,PSME2,TP53,SOD2,P2RX7,ERBB2,COL18A1,STIL,PHLDA1,BCAP31,ARHGEF16,IER3,SRPX,KIF14,PLCG2,SMO,BCL6,TWIST1,STEAP3,APIP,EGLN3,F2R,CTH,CHP1,PPIF,SIRT1,BAG4,AKT1,FIGNL1,GLO1,CD40,MAP3K6,CASP4,SOCS3,PTGS2,BHLHB9,PSMD3,TLE1,IRF7,CHMP4B,ARHGAP4,LIFR,CBX4,ZC3HC1,FAM134B,BIN1,GCLM,PINK1,CPEB4,ARHGEF11,DAP,CTSB,ARHGEF7,SERPINB9,PSMD10,SELL,GDF15,AES,TGFBR1,TOP2A,CARD8,ADORA1,BMP7,TFAP2A,SGK1,BUB1,KANK2,FAIM,DUSP1,RHOA,ADAM17,PSMB4,WNT10B,HMGN5,PLAUR,GCLC,RGCC,PPARA,TRIM35,PELI3,BCAR1,MAPK8IP1,BCL10,CASP7,SCG2,DHRS2,E2F1,ARRB1,SOX8,ARHGEF9,HIPK3,ARHGEF4,NGEF |
| 1.724e-12 | -27.09 | large_intestine | COSMIC cancer mutations | large_intestine | 17444 | 2575 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ABRACL,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,RHBDL3,PTTG1,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,IL22RA1,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,GPR107,CAPN12,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,CEP41,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.788e-12 | -27.05 | GSE10325_BCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_BCELL_VS_LUPUS_BCELL_DN | 193 | 67 | 17758 | 2588 |
DLGAP5,PSME2,SUZ12,DNAJC3,TAP1,PDIA5,PSME1,PJA2,SDC1,BTG3,IFIT1,ACSL4,OAS3,TIPARP,TRAM1,APOBEC3G,NAGA,MX1,PPIF,LAMP2,LAP3,USP18,ITCH,SAT1,CCBL2,EAF2,OPTN,DDOST,RBM47,STAT1,IRF7,SLC31A2,CDS2,LGALS3,MAN1A2,HLA-E,CDCA8,HERC5,HMGN3,NDUFA4,RAB6A,HERC6,DUSP5,HLA-A,CTSC,PRKCI,MOXD1,PSMA5,GFPT1,REC8,HMMR,PLSCR1,MICB,RAPGEF2,GGH,BLVRA,IFIT3,KIF11,RHOB,FAS,BCAR3,TMEM30A,SLC25A40,NMI,ZMIZ1,IFI6,SRSF9 |
| 1.799e-12 | -27.04 | regulation of hydrolase activity | biological process | GO:0051336 | 1252 | 276 | 16441 | 2455 |
PPP4R4,RET,XIAP,PSME1,SNX9,RIC1,ELMOD2,CALM2,ARHGAP42,RGS12,CTGF,RGS3,DNM2,CRY2,TIAM1,ACVR1C,CASP9,PRKAR2B,POR,ARF4,ABR,ARHGEF26,PLCG1,SH2D3C,PPP2R4,AGFG2,SERPINB6,SERPINI1,STARD13,FGD1,TBC1D1,NUAK1,ITGA6,SH3RF2,TFAP4,RALGPS2,CYR61,SNX18,RANBP1,FAM13B,MSH2,DAPK1,PRKG1,SORL1,MAPK7,PPP6R1,TMED2,TBC1D8B,CALM1,EPHA1,CYFIP2,PLIN5,RASA1,FAS,FNTA,HTT,SEMA4D,ITPR1,ARAP1,FGD6,MAP3K5,SERPINB1,RPS6KA3,XDH,EGLN1,DOCK9,PLEKHG3,ARHGAP11A,SPRED1,RPS6KA1,IQGAP1,CAST,RALBP1,PTTG1,RGS20,PRKACA,EPS8L2,APLP2,ST5,ACAP2,SH3BP1,FICD,TAX1BP3,CDKN1B,DAB2IP,IFIT1,RASGEF1A,DLG3,CDKN2D,TBC1D10B,DOCK4,CAMSAP3,SLC11A2,ATP1B1,PKMYT1,ITPR3,PPP2R5A,NGFRAP1,CORO1C,SIPA1L1,PLEKHG1,RGS14,DENND5B,MAPK12,PRKAR1A,ARHGEF3,FARP1,PCOLCE,HSP90B1,NKX3-1,DEPDC1,TRAF2,ARHGEF40,TIPRL,ICAM1,CTSC,KNDC1,GPC3,MCF2L,CST3,BAX,TMBIM6,RAG1,SPRY2,MSH6,FARP2,RASGRF1,ARAP2,ARHGEF28,PLSCR1,DENND1B,RAPGEF2,FURIN,RAB3IP,GRTP1,TXK,GPLD1,RGS9,TIMP3,KIAA0141,FGFR2,PRDX3,RCBTB2,RIN3,ARFGAP3,SERPINB5,GPER1,CPEB2,CASP3,AGRN,EPHA4,ARFGEF1,DNAJB11,F11R,ITPR2,DENND2D,ARHGEF10L,SIPA1L2,PCNA,RABEP2,NPNT,ARHGEF37,CDKL5,ARL1,RGS5,RP2,SLC39A10,RASGRP1,SOD1,ARHGDIB,VCP,EDNRA,PLEKHG6,NEIL1,ARHGEF19,TBC1D17,MADD,RAP1GAP,PPP2R5D,LMTK3,ARAP3,PPP1R12A,SERPINE2,PPP1R2,BVES,RASA2,CALM3,RACGAP1,DOCK11,FBLN1,BMP2,TIMP1,RINL,OCRL,TBCD,PAK2,FNIP1,WNT3A,PLCB2,ALS2CL,SPATA13,FBXO8,SCRIB,BCL2L13,EGFR,RASGRP2,BCAR3,GNAS,TSC1,SH3BP4,ATP1B3,IFI6,PROM2,PSME2,TP53,ERBB2,RASGRP3,BCAP31,SYTL2,ARHGEF16,PPME1,BCL6,OAS3,TMEM64,EGLN3,F2R,HSPA2,GM2A,CHP1,PPIF,SIRT1,BAG4,TIMP2,AKT1,CD40,DOCK5,ARHGAP35,DNAJC10,EFNA5,ARHGAP4,PPP2R2D,ARFGEF3,SORT1,PINK1,ARHGEF11,ARHGEF7,DAP,SERPINB9,SBF1,AIP,SH2D4A,PPP2R3A,SYDE2,CD109,SNX13,CARD8,ADRBK1,LLGL2,IQGAP3,RPGR,RHOA,PLAUR,STMN3,COL7A1,LEPR,BCL10,ARHGAP24,CASP7,SERPINA1,SPINT2,ARRB1,TBC1D4,ARHGEF9,RAB3IL1,ARHGEF4,NGEF |
| 1.814e-12 | -27.04 | BAELDE_DIABETIC_NEPHROPATHY_DN | MSigDB lists | BAELDE_DIABETIC_NEPHROPATHY_DN | 420 | 116 | 17758 | 2588 |
EXPH5,MYL9,BCAM,UGP2,AGRN,AASS,GRIK2,CAST,NDRG1,TSC22D3,TMX4,CTDSPL,TAP1,KBTBD11,CHST2,CDS1,PLS3,PDGFA,NAPG,PHYHIP,TGFBR3,CTGF,SP100,EFR3A,ARL1,PLCG2,PAPSS1,ATP13A3,RPN2,IFIT1,F2R,LOXL1,HSPA2,CYP1B1,SEMA3B,SMARCA2,CD55,ING1,ACBD3,DSTN,HSPA12A,RNF11,NFE2L1,PTGER4,KLK6,PRKAR2B,GTF2A2,MYL12A,DAG1,ULK2,RHEB,OPTN,DPYSL3,TAPBP,ALDH3B1,TRAM2,FYN,DNM1L,GDE1,AXL,HOXA9,MYLK,LRIG1,STAT1,ARF6,MAFF,PRKAR1A,HSP90B1,CDKN1C,SEC61G,ATP9A,GNE,SDC4,PDIA3,HMGN3,TRIB2,VPS26A,DNAJB9,BMP2,CAPN2,CTNNBIP1,KIF5B,ADD3,ADORA1,ITGA3,FRY,TIMP1,CYR61,CALD1,BMP7,MSH2,PRKCI,WWP1,IGFBP2,NPTN,CITED2,DUSP1,PLSCR1,NR3C1,LITAF,BCAR3,UAP1,PVRL2,CCDC6,PLOD2,FGFR2,PHLPP2,NMI,UBE2D2,RHOBTB2,OSMR,KLK7,ACADM,ITGAV,CTBP1,TOB1 |
| 1.823e-12 | -27.03 | other | COSMIC cancer mutations | other | 15619 | 2374 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,TMEM173,DMPK,WDR63,RNF224,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,KLK7,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,NRG2,LYNX1,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,ZNF502,TRPC3,EGLN1,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ZNF230,AK3,ITM2C,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,RUSC2,DAP,GNE,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,CAMK2G,IGDCC4,MLEC,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,OCLN,HEBP1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ASCL5,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,CPEB4,SCD5,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,ERBB3,MSH6,TGIF1,ZWINT,LONRF3,PAPD7,TCFL5,TMEM221,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,FAM81A,QSOX2,TYW3,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.893e-12 | -26.99 | Kinase-like_dom | interpro domains | IPR011009 | 524 | 137 | 18293 | 2672 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,CAMK1D,PAK6,DAPK2,WEE1,RPS6KA2,CDKL5,PASK,PIK3CA,PIK3CD,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,ROR1,AURKB,STK17B,ADRBK2,CDK1,ULK2,PLK2,LIMK1,MYLK,MAP3K11,MAPK13,PIK3C2B,RNASEL,PRKAA2,CDK17,LMTK3,NUAK1,PRKAA1,ADCK5,TEC,MERTK,BMP2K,IGF1R,PAK2,PRKCI,DAPK1,ADCK2,PRKG1,NEK2,MAP3K9,ALPK1,PIM1,MAPK7,MAST4,PHKG2,ADCK3,MAPKAPK3,TESK1,STRADB,EIF2AK1,EPHA1,ILK,PDIK1L,EGFR,STK17A,MAPKAPK2,INSR,CSNK1G1,ALPK3,AURKA,CDK18,STK39,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,RPS6KA1,ETNK1,TESK2,ERBB2,MAPK4,GRK6,PRKACA,DDR1,FLT3,CDK14,PLK4,EPHB4,SCYL3,MAP3K3,RIPK2,AKT1,PRKCQ,PKMYT1,MAP3K6,EPHA10,FYN,JAK1,CDK19,STK26,ACAD10,AXL,STK38,PTK7,KIAA1804,MLKL,MAPK12,TAOK2,DYRK3,PINK1,CIT,TGFBR1,TRIB2,PKN1,ADRBK1,IRAK1,CDK16,KNDC1,SGK3,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,CASK,PIM3,YES1,TXK,ACVRL1,FGFR2,RYK,LRRK1,HIPK3,MELK |
| 1.954e-12 | -26.96 | stomach-carcinoma | COSMIC cancer mutations | stomach-carcinoma | 446 | 121 | 17775 | 2585 |
TNK1,ACVR1,TRIM24,CAMKK1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,FLT3,DDR1,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,PLK4,EPHB4,PIK3CD,SCYL3,STK35,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,MAP3K6,ADRBK2,STK17B,ULK2,EPHA10,FYN,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MYLK,KIAA1804,MAP3K11,MAPK13,PIK3C2B,RNASEL,MLKL,MAPK12,PRKAA2,PINK1,DYRK3,TAOK2,CDK17,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,IGF1R,IRAK1,ADRBK1,CDK16,PTEN,NEK2,DAPK1,PRKCI,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,PIKFYVE,MAPK7,MAP3K7,SYK,PHKG2,CAMK2G,MSH6,CASK,TESK1,PIK3R1,PIP4K2C,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,EGFR,TXK,STK17A,MAPKAPK2,INSR,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,RPS6KA3,MELK,DMPK |
| 1.971e-12 | -26.95 | ovary-carcinoma-mucinous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mucinous_carcinoma | 466 | 125 | 17775 | 2585 |
TNK1,ACVR1,NF2,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,FLT3,DDR1,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDH1,CDKL5,PIK3CA,PLK4,EPHB4,SCYL3,STK35,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,IDH1,MAP3K6,ADRBK2,STK17B,ULK2,EPHA10,FYN,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MYLK,KIAA1804,MAP3K11,MAPK13,RNASEL,MLKL,MAPK12,PRKAA2,PINK1,DYRK3,TAOK2,CDK17,PRKAA1,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,RB1,IGF1R,IRAK1,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,PRKCI,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MAPK7,MAP3K7,SYK,PHKG2,CAMK2G,MSH6,CASK,ADCK3,TESK1,PIK3R1,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,EGFR,TXK,STK17A,GNAS,MAPKAPK2,INSR,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,RPS6KA3,MELK,DMPK |
| 2.161e-12 | -26.86 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 16661 | 2497 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,PTTG1,APOO,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,PARM1,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,GPR107,CAPN12,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 2.177e-12 | -26.85 | lung-carcinoid-endocrine_tumour | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour | 512 | 134 | 17775 | 2585 |
TNK1,PNISR,ACVR1,LGR4,CAMKK1,EPHA4,RET,CAMK1D,SDC1,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,IL6ST,PIK3CA,FUT1,STK35,PLK1,NEK4,SMARCA2,MARK1,ACVR1C,PBK,ROR1,AURKB,IDH1,ADRBK2,STK17B,ULK2,PLK2,LIMK1,MYLK,MAP3K11,MAPK13,RNASEL,TANC2,PRKAA2,CDK17,PRKAA1,ADCK5,MERTK,PSIP1,BMP2K,IGF1R,NEK2,DAPK1,PRKCI,MAP3K9,ADCK2,PRKG1,ALPK1,PIM1,ZRANB1,MAPK7,PHKG2,SYTL3,ADCK3,TESK1,ZNF320,STRADB,EIF2AK1,PDK3,PDIK1L,GNA11,EGFR,STK17A,DHX32,MAPKAPK2,INSR,ALPK3,AURKA,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,RPS6KA1,TP53,TESK2,ERBB2,GRK6,PRKACA,DDR1,FLT3,CDK14,PLK4,EPHB4,SCYL3,MAP3K3,AKT1,RIPK2,PRKCQ,PKMYT1,MAP3K6,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,MAPK12,TAOK2,DYRK3,PINK1,TGFBR1,PKN1,TRIB2,ADRBK1,IRAK1,PTEN,CDK16,SGK3,SGK1,ATP8B1,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,CASK,YES1,TXK,MAP1B,FGFR2,ACVRL1,HIPK3,MELK |
| 2.353e-12 | -26.78 | skin | COSMIC cancer mutations | skin | 17124 | 2546 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ABRACL,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,TMEM200B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,IL22RA1,VPS26A,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,NDRG1,CERCAM,RALBP1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 2.477e-12 | -26.72 | enzyme linked receptor protein signaling pathway | biological process | GO:0007167 | 1013 | 232 | 16441 | 2455 |
CCNC,MYL9,LTBP1,CASP3,TNK1,ACVR1,RET,EPHA4,NRG2,F11R,PDGFRL,PSME1,ITPR2,PDGFB,SPTB,SH3KBP1,CALM2,ZFYVE16,ZYX,RPS6KA2,PSMD1,TGFBR3,CTGF,ELMO2,SHC3,ZCCHC12,IL6ST,PSMC2,IL31RA,PIK3CA,PIK3CD,MYH14,PPP1CA,TIAM1,PTPRE,TIPARP,RASGRP1,ACVR1C,CASP9,PRKAR2B,AGO4,ROR1,ZFAND5,ARF4,ABR,RHEB,PGF,PLCG1,AREG,LIMK1,CAB39,HDAC1,CTNND1,MAPK13,EIF4EBP2,HSPB1,GAB1,PPP2R5D,PSMC1,MYL12B,RRAGD,PCSK5,FGD1,PRKAA2,RUNX2,RASA2,SOX9,PRKAA1,PSMD7,ATP6V1E2,CALM3,TEC,NCKAP1,PHLPP1,DUSP5,BMP2,IGF1R,MEGF8,FLRT3,PAK2,PRKCI,NPTN,C10orf54,MAPK7,NCAM1,PSMA5,SOCS5,RGMB,MAPKAPK3,CALM1,STRADB,EPHA1,ELK1,CYFIP2,PSMA4,EGFR,RASA1,CDK5R1,PTPRF,MAPKAPK2,TSC1,FNTA,INSR,PRKAG2,PHLPP2,CSF1,NFKBIA,ITPR1,EFNA1,LTBP2,GDF11,ARPC2,JAK3,TOB1,RPS6KA3,SPRED1,SORBS1,REPS2,RPS6KA1,IQGAP1,PSME2,SLC2A8,TP53,ERBB2,RASGRP3,PRKACA,DDR1,FLT3,ARHGEF16,ZFYVE9,PDGFA,ATP6V0B,SS18,RALB,DOK4,CDKN1B,DAB2IP,EPHB4,RASGEF1A,FRS3,SULF2,AKT1,RIPK2,PTPRU,ERBB2IP,CBL,ITPR3,DUSP4,MYL12A,GIGYF1,SOCS3,EPHA10,IRS2,IDE,PTPRJ,FYN,JAK1,RBL1,NGFRAP1,SLC9A6,AXL,PSMD3,WWTR1,SIPA1L1,STAT1,PPP1CB,SPTBN5,NRG1,EFNA5,ARHGAP4,RGS14,LIFR,MAPK12,PRKAR1A,ARHGEF3,TNRC6C,SORT1,MPZL1,ARHGEF11,ARHGEF7,EPS8,LRP4,PSMD10,TGFBR1,GDF15,EFNB1,FGF19,NRP2,SGPL1,ADRBK1,IRAK1,PTEN,MCF2L,BMP7,FUT8,MAPK11,ERBB3,MAP3K7,CITED2,SPRY2,SYK,CAMK2G,RASGRF1,TGIF1,PDGFC,RHOA,ARHGEF28,ADAM17,PSMB4,NR4A1,RAPGEF2,PIK3R1,GRIN1,FURIN,AKAP3,YES1,FOS,BCAR1,TXK,GPLD1,CD8A,ACVRL1,FGFR2,TWSG1,FGF18,GRIN2D,ITGAV,ATP6V1C1,ARHGEF9,ARHGEF4,RGMA,NGEF |
| 2.716e-12 | -26.63 | mucinous_carcinoma | COSMIC cancer mutations | mucinous_carcinoma | 468 | 125 | 17775 | 2585 |
TNK1,ACVR1,NF2,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,FLT3,DDR1,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDH1,CDKL5,PIK3CA,PLK4,EPHB4,SCYL3,STK35,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,IDH1,MAP3K6,ADRBK2,STK17B,ULK2,EPHA10,FYN,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MYLK,KIAA1804,MAP3K11,MAPK13,RNASEL,MLKL,MAPK12,PRKAA2,PINK1,DYRK3,TAOK2,CDK17,PRKAA1,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,RB1,IGF1R,IRAK1,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,PRKCI,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MAPK7,MAP3K7,SYK,PHKG2,CAMK2G,MSH6,CASK,ADCK3,TESK1,PIK3R1,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,EGFR,TXK,STK17A,GNAS,MAPKAPK2,INSR,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,RPS6KA3,MELK,DMPK |
| 2.804e-12 | -26.60 | brain | COSMIC cancer mutations | brain | 17017 | 2535 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,FLYWCH2,CAMKK1,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,ZMYM1,MYLIP,KANK3,ULBP2,DGKG,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,PARM1,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,CAPN12,GPR107,REPS2,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 2.834e-12 | -26.59 | HALLMARK_MITOTIC_SPINDLE | MSigDB lists | HALLMARK_MITOTIC_SPINDLE | 199 | 68 | 17758 | 2588 |
KIF3C,DLGAP5,RALBP1,NDC80,ARFGEF1,KIF2C,CNTROB,HDAC6,CNTRL,DLG1,KIF22,CTTN,TIAM1,TUBA4A,PLK1,DOCK4,PCGF5,UXT,EZR,NUSAP1,PIF1,ANLN,CDK1,ABR,NIN,MID1IP1,MAP3K11,ARF6,ARHGAP4,BIN1,ARAP3,TAOK2,FARP1,ARHGEF3,ARHGEF11,RASA2,ARHGEF7,KIF23,RACGAP1,NOTCH2,SAC3D1,CKAP5,TOP2A,KIF5B,CENPJ,TBCD,TUBGCP6,NEK2,PRC1,BUB1,KNTC1,CLIP2,CCDC88A,SMC4,SUN2,KIF20B,KIF11,BCAR1,RANBP9,RASA1,TSC1,AURKA,FGD6,PKD2,CENPE,SHROOM2,CCNB2,ESPL1 |
| 3.103e-12 | -26.50 | DELYS_THYROID_CANCER_UP | MSigDB lists | DELYS_THYROID_CANCER_UP | 438 | 119 | 17758 | 2588 |
KLK10,AGRN,ST14,S100A11,GALNT12,EPHA4,IL13RA1,PLA2G16,SDC1,CHST2,IER3,CCND1,DAPK2,APLP2,RPS6KA2,RGS3,ALDH1A3,PAPSS1,PASK,CAPG,TAX1BP3,CDH3,TACSTD2,ECE1,CTTN,ETHE1,ARMCX6,TIAM1,TIPARP,PTPRE,S100A13,IL1RAP,CKS2,CYP1B1,CPD,CD55,PTPRU,S100A4,KDELR3,KLK6,ARHGDIB,LOXL2,ROR1,DUSP4,ITPR3,MAP3K6,TP53I3,ABR,DPYSL3,MDK,ALDH3B1,FYN,GPRC5B,AREG,MAP2,KCNK1,PTK7,P4HA2,CORO1C,STAT1,MAPK13,PLXND1,MRC2,IGFBP6,LGALS3,CTSB,LRP4,SDC4,EPS8,ETV5,PBX3,GDF15,CRABP2,DHRS3,S100A2,DUSP5,NRP2,ICAM1,ELF3,SPP1,FLII,ADORA1,ITGA3,TIMP1,CTSC,KCNK5,KCNN4,FJX1,AIM1,FXYD5,ERBB3,CTSD,IGSF3,NFE2L3,QSOX1,DDB2,PRSS23,MAPKAPK3,BCL9,UBE2A,PDE5A,EMP3,NPC2,CYFIP2,STX3,FAS,KLHL2,PTPRF,ENDOD1,SERPINA1,COL13A1,NAB2,DTX4,S100A5,CTSA,ATP1B3,MAP3K5,ACOT7,DOCK9 |
| 3.147e-12 | -26.48 | CHANG_CYCLING_GENES | MSigDB lists | CHANG_CYCLING_GENES | 141 | 54 | 17758 | 2588 |
CASP3,MZT1,DLGAP5,HJURP,DEPDC1,FOXM1,TUBB4B,CKAP2,PTTG1,CDCA8,KIF23,NUF2,SDC1,BARD1,SCML1,TOP2A,PCNA,CCNA2,UBE2T,TIMP1,CDKL5,KIF22,BUB1,USP1,IFIT1,SMC4,CKS2,TUBA4A,HMMR,PLK1,PSRC1,CENPA,PBK,CKAP2L,NUSAP1,KIF20B,ANLN,CCNF,CDC25C,CDK1,G2E3,PRIM1,ANKRD10,FAM64A,PRPS2,CDCA5,FAM83D,E2F1,AURKA,DONSON,MAPK13,CCNB2,UBE2C,MELK |
| 3.324e-12 | -26.43 | MODULE_6 | MSigDB lists | MODULE_6 | 399 | 111 | 17758 | 2588 |
MYL9,LTBP1,TRIM2,NQO1,HSPG2,EPAS1,S100A11,CRYM,DGKA,SDC1,DDR1,ECI1,ARHGEF16,CHPF,IER3,CCND1,EPCAM,ZYX,CYP1A1,ST5,SCNN1A,CDH1,LMO4,ALDH1A3,FOSB,DNM2,BCL6,CLDN4,TACSTD2,NOTCH3,LGMN,TSPAN1,CPE,HSPA2,CYP1B1,CPD,SGCE,CD55,COL6A2,PTPRU,S100A4,ITPR3,ALCAM,DPYSL3,MDK,ALDH3B1,HLF,AGPAT2,WWTR1,MYLK,BMP1,MAOA,KLF5,PDXK,MAFF,GRN,PRSS8,COL9A3,PCOLCE,IGFBP6,ATP9A,ITGA6,SOX9,GNE,ASAH1,GDF15,NUCB2,SEPP1,DHRS3,S100A2,FBLN1,HOXB2,DUSP5,ELF3,M6PR,TMEM63A,RAC2,CYR61,CTSC,LLGL2,CD22,GPC3,KCNN4,COL6A1,IGFBP2,ERBB3,CITED2,SLC12A2,EPHX1,HES1,PRSS23,NR4A1,GCLC,EMP3,FOS,RHOB,CYB5A,EGFR,FUCA1,TIMP3,PROM1,SERPINA1,ETS2,ITGA7,DTX4,RAB31,SERPINB5,STK39,EFNA1,GEM,SERPINB1 |
| 3.565e-12 | -26.36 | positive regulation of hydrolase activity | biological process | GO:0051345 | 828 | 197 | 16441 | 2455 |
CASP3,AGRN,RET,ARFGEF1,DNAJB11,F11R,PSME1,ITPR2,SNX9,DENND2D,RIC1,ELMOD2,CALM2,ARHGEF10L,SIPA1L2,PCNA,ARHGAP42,RGS12,CTGF,RABEP2,NPNT,ARHGEF37,CDKL5,ARL1,RGS3,DNM2,RGS5,RP2,SLC39A10,TIAM1,RASGRP1,ACVR1C,CASP9,ARHGDIB,PRKAR2B,ARF4,VCP,ABR,ARHGEF26,EDNRA,PLCG1,PLEKHG6,TBC1D17,ARHGEF19,SH2D3C,PPP2R4,MADD,AGFG2,RAP1GAP,STARD13,FGD1,ARAP3,PPP1R12A,TBC1D1,ITGA6,RASA2,CALM3,RACGAP1,DOCK11,FBLN1,BMP2,TFAP4,RALGPS2,CYR61,SNX18,RINL,OCRL,RANBP1,FAM13B,TBCD,MSH2,DAPK1,FNIP1,WNT3A,PLCB2,ALS2CL,TBC1D8B,CALM1,SPATA13,FBXO8,SCRIB,EPHA1,BCL2L13,CYFIP2,EGFR,PLIN5,RASA1,FAS,RASGRP2,GNAS,BCAR3,TSC1,FNTA,SEMA4D,ITPR1,ARAP1,FGD6,ATP1B3,MAP3K5,XDH,DOCK9,PLEKHG3,ARHGAP11A,IQGAP1,PSME2,RALBP1,RGS20,ERBB2,RASGRP3,PRKACA,BCAP31,ARHGEF16,EPS8L2,ST5,ACAP2,SH3BP1,TAX1BP3,CDKN1B,DAB2IP,RASGEF1A,EGLN3,F2R,HSPA2,GM2A,TBC1D10B,DOCK4,SIRT1,AKT1,SLC11A2,ATP1B1,ITPR3,CD40,DOCK5,ARHGAP35,DNAJC10,NGFRAP1,CORO1C,SIPA1L1,PLEKHG1,RGS14,ARHGAP4,MAPK12,PRKAR1A,ARFGEF3,DENND5B,ARHGEF3,PINK1,FARP1,NKX3-1,PCOLCE,DEPDC1,ARHGEF11,DAP,TRAF2,ARHGEF7,SBF1,ARHGEF40,ICAM1,SYDE2,SNX13,CARD8,ADRBK1,CTSC,LLGL2,KNDC1,MCF2L,BAX,IQGAP3,RPGR,MSH6,FARP2,RASGRF1,ARAP2,RHOA,ARHGEF28,PLSCR1,DENND1B,RAPGEF2,RAB3IP,GRTP1,GPLD1,TXK,BCL10,ARHGAP24,RGS9,CASP7,FGFR2,RCBTB2,RIN3,ARFGAP3,ARRB1,GPER1,TBC1D4,ARHGEF9,RAB3IL1,ARHGEF4,NGEF |
| 3.570e-12 | -26.36 | phosphorylation | biological process | GO:0016310 | 1198 | 265 | 16441 | 2455 |
ACVR1,TRIM24,AK7,RET,CUL1,NRG2,PSME1,IL18,CAMK1D,CCNB1,PICK1,GRM5,CALM2,PAK6,DAPK2,WEE1,PSMD1,TGFBR3,IL31RA,PIK3CA,PIK3CD,NEK4,ACVR1C,PBK,AURKB,ULK2,PLK2,SH2D3C,LIMK1,GNPTAB,MYLK,NOD2,MAP3K11,DHTKD1,MAPK13,RNASEL,ITPKA,GAB1,CDK17,NUAK1,DGKQ,SOX9,PRKAA1,NDUFA4,TNFRSF19,MERTK,BMP2K,PPP4R1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,NCAM1,MAPK7,MAST4,DGKG,PHKG2,PMPCB,MMD,ADCK3,MAPKAPK3,STAT4,CALM1,PIP4K2C,EPHA1,PKM,ELK1,ILK,PSMA4,RASA1,STK17A,DGKH,NT5C2,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,NRBP1,RPS6KA3,DMPK,SPRED1,PAPSS2,RPS6KA1,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,CCND1,DOK4,DAB2IP,EPHB4,PHKA2,RASGEF1A,RIPK2,PFKFB2,PANK1,PRKCQ,PKMYT1,XRCC6BP1,EPHA10,IRS2,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,NRG1,PDXK,MLKL,MAPK12,GALK1,TAOK2,CCM2,PKN1,FGF19,IRAK1,FAM20B,SGK3,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,RASGRF1,CASK,RAPGEF2,PIK3R1,GRIN1,AK4,PIM3,YES1,FOS,TXK,FGFR2,ACVRL1,RYK,PGM2L1,GRIN2D,ITGAV,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,PDGFB,SPTB,RPS6KA2,CDKL5,SHC3,IMPAD1,PASK,PSMC2,PAPSS1,DUSP10,RASGRP1,STK35,PLK1,MARK1,ROR1,PRKRA,ADRBK2,STK17B,CDK1,PI4K2B,FASTKD1,CAB39,PIK3C2B,PPP2R5D,PSMC1,PRKAA2,LMTK3,RASA2,PSMD7,CALM3,ADCK5,TEC,DUSP5,BMP2,IGF1R,PFKL,FAM20C,PAK2,PRKCI,MDFIC,PIM1,NPTN,PSMA5,MDFI,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,CDK5R1,EGFR,MAPKAPK2,INSR,PRPS2,ALPK3,JAK3,CTBP1,IL15,PSME2,DGKA,P2RX7,ERBB2,RASGRP3,CDK14,PDGFA,PLK4,F2R,SCYL3,SEPHS1,FRS3,MAP3K3,AKT1,RFK,PTGER4,DUSP4,MAP3K6,PTK7,STK38,PSMD3,SPTBN5,ST3GAL1,DYRK3,PINK1,ENO2,TAB3,CIT,GNE,PSMD10,TGFBR1,TRIB2,ADRBK1,CDK16,SGK1,BUB1,IQGAP3,SYK,CAMK2G,PGM1,PSMB4,OGDHL,NADK2,RUNX3,MAPK8IP1,DGKE,PRDX4,SCG2,FGF18,HIPK3 |
| 3.660e-12 | -26.33 | AACTTT_UNKNOWN | MSigDB lists | AACTTT_UNKNOWN | 1782 | 361 | 17758 | 2588 |
HSPG2,VANGL1,FBXO2,CUL1,C1orf198,MORF4L2,CAMK1D,CALM2,WEE1,PHYHIP,SESN3,ELMO2,STIM1,RGS3,CABP1,FOSB,STEAP2,KCNS3,MANF,WBP4,LAMP2,SMARCA2,ACVR1C,SNTB2,SH3BGRL,SERTAD4,CDYL,PRKAR2B,SAV1,LDB2,RNF19B,PIAS3,NKD1,BMP1,EIF4EBP2,SERPINI1,ARF6,F2RL1,HSPB1,STARD13,ANXA11,SCN5A,CDK17,INPPL1,ALDH6A1,CALB2,SOX9,RAB23,C6orf106,ISYNA1,SLC1A3,APBA1,MERTK,TNFRSF19,TSPAN7,LMNA,MECOM,TFAP4,SH3D21,CYR61,SLC16A6,FLRT3,ZIC5,CACNA1D,PIKFYVE,MOXD1,MAST4,MYLIP,MMD,TBC1D8B,CALM1,WHSC1,NPC2,KDM3A,NFIB,SFXN5,RHOB,DGKH,PTPRF,NCOA3,AP1AR,PRKAG2,PIAS2,MPP2,NR4A2,CDK18,STK39,ARPC2,HOOK1,RPS6KA3,IRF1,SLC2A4,ARMCX3,GRHL2,REPS2,RALBP1,C5orf30,IRX4,RNF182,BLCAP,EGR3,CD274,GRK6,FAM91A1,SNN,REPS1,APPBP2,CDS1,RNF220,CDH1,DACT1,XYLT2,TNPO2,ACSL4,PDE4D,OSBPL7,ETV4,MYT1,DOCK4,CAPN6,SYNE2,CDCA2,PYGO1,ALCAM,SP4,EBF2,FZD7,PDLIM3,AXL,NRG1,HS3ST3B1,PRIMA1,NR3C2,CBX7,PRR15,IER5L,FARP1,SLC16A14,GCAT,MAN1A2,TRAF2,SDC4,PBX3,NUCB2,ZNF219,SEPP1,SRPX2,HOXB2,NFAT5,PDIA4,WWP2,DTX3L,ADD3,PDCD10,OXCT1,RNF128,PTEN,ANKS1B,CALD1,GPC3,FAM20B,MAPK11,NPTXR,ITM2C,SPRY2,NCOA2,ACBD5,ADAMTS2,TGIF1,ARAP2,TEF,BCL9,EIF5A2,PIK3R1,UBE2A,LRRC1,FOS,PITX2,NUCB1,BTG1,TIMP3,RCBTB2,FGFR2,NR4A3,FBXO44,FZD5,OSR1,SHOX2,CPEB2,FOXA1,MELK,JARID2,RGMA,CCNC,LTBP1,TRIM2,PPM1J,HEBP1,ARFGEF1,MPP5,PDGFB,SPTB,SH3KBP1,NKAIN3,RPS6KA2,CTNNB1,CDKL5,SHC3,TSPAN6,IL6ST,MITF,TRPC1,DUSP10,RP2,BTBD3,FGFR1OP2,ZNF462,TDP1,PCGF5,TRIM8,CXXC5,ING1,ACBD3,NFE2L1,RGAG1,TNFAIP8L1,ROR1,PTGFRN,SESN1,ZBTB7B,DPYSL3,IRX3,CXXC4,KLF12,GPRC5B,CTNND1,RRAGD,PCSK5,RMND5A,PRKAA2,LASP1,BMF,LRRFIP2,PPP1R12A,CHCHD7,ETV5,ASB9,CALM3,CNTNAP2,FAM81A,DOCK11,DHRS3,IL18R1,SPP1,IGF1R,FRAS1,PRKCI,RFX5,KNTC1,NTN1,SLC12A2,CCDC88A,MDFI,CYP26B1,ELK3,OXR1,C3orf58,NMT2,SOX13,GNAS,BCAR3,EPN3,TSC1,UAP1,COL13A1,H1F0,NFKBIA,PAPD5,SH3BP4,NXPH4,SEMA3A,CCNB2,TOB1,RAD21,NCKAP5,PAX6,SORBS1,HOXB7,NF2,UGP2,TP53,ERBB2,FAM198B,BCAP31,CYP26A1,SYTL2,KCTD9,RAD23A,SAP130,KCTD15,PPME1,LHX6,BCL6,STEAP3,EGLN3,NFKB2,SEPHS1,MAP3K3,SOAT1,CLCN3,TMTC2,MYL12A,PTGS2,TLE1,EFNA5,RCAN2,REEP4,ST3GAL1,NDST3,ZC3HC1,CMTM4,CTDSP1,PACSIN2,TM2D2,TAB3,ARHGEF11,POC1B,ARHGEF7,COL4A5,PPP2R3A,NRP2,ZDHHC21,IRF2BPL,FOXP2,KIF5B,ADRBK1,TOX2,TFAP2A,CKS1B,ARVCF,ABCD1,KANK2,HES1,ADAM17,MLEC,DCAF6,MOSPD2,HMGN5,CRB3,NR3C1,PRICKLE1,TCEAL8,MAP1B,PRDX4,SCG2,RAP2C,PGRMC1,NETO2,GEM,UBE2C,DIS3L |
| 3.768e-12 | -26.30 | neoplasm | COSMIC cancer mutations | neoplasm | 15558 | 2365 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,TMEM173,DMPK,WDR63,RNF224,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,KLK7,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,NRG2,LYNX1,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,ZNF502,TRPC3,EGLN1,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ZNF230,AK3,ITM2C,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,RUSC2,DAP,GNE,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,CAMK2G,IGDCC4,MLEC,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,SGK3,PRC1,ATP8B1,ERCC2,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,OCLN,HEBP1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ASCL5,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,TMEM37,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,CPEB4,SCD5,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,IL22RA1,VPS26A,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,ERBB3,MSH6,TGIF1,ZWINT,LONRF3,PAPD7,TCFL5,TMEM221,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,FAM81A,QSOX2,TYW3,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 3.844e-12 | -26.28 | EGFR_UP.V1_UP | MSigDB lists | EGFR_UP.V1_UP | 183 | 64 | 17758 | 2588 |
PAPSS2,IL15RA,EPAS1,TAP1,SOD2,CCDC68,PLAC1,PHLDA1,KTN1,APOBEC3B,CTGF,AOX1,KCNS3,SNX16,ARNT2,ETHE1,EGLN3,NFKB2,PTPRE,HSPA2,CYP1B1,SEC23A,SAT1,LOXL2,DUSP4,LHFPL2,SGPP1,ENPP1,WIPI1,SLC9A6,MAOA,F2RL1,GCLM,ETV5,DUSP5,ICAM1,RND1,CAPN2,TNS3,ITGA3,CYR61,MGAT4A,BMP7,DRAM1,CADPS2,SLC12A2,GCNT1,ELK3,ARAP2,CTNNAL1,IFIT3,SPTLC2,EGFR,SPAG1,CRISPLD2,IL1R1,NT5C2,CASP7,ETS2,CSGALNACT1,ARFGAP3,MAP3K5,RPS6KA3,IRF1 |
| 3.844e-12 | -26.28 | - | gene3d domains | 2.30.29.30 | 379 | 112 | 9988 | 1574 |
PLEKHG3,SPRED1,MTM1,NF2,FAM129B,SPTB,ARHGEF16,EPS8L2,ARHGEF10L,ACAP2,ARHGAP42,RGS12,ELMO2,SHC3,DOK4,OSBPL3,RGS3,PLCG2,DNM2,DAB2IP,RTKN2,EPB41L4B,OSBPL7,TLN2,TIAM1,FRS3,AKT1,PLEKHO1,EZR,TNS1,ANLN,ADRBK2,ARHGEF26,PLEKHB1,ABR,TNS4,IRS2,PLCH1,PLEKHG6,PLCG1,ARHGEF19,MPRIP,TRIOBP,PLEKHG1,SPTBN5,EPB41L4A,APBA2,GAB1,FGD1,ARAP3,ARHGEF3,FARP1,FRMD4A,ARHGEF11,PLEKHJ1,TBC1D1,CIT,FRMD6,ARHGEF7,RASA2,EPS8,CCM2,PLD2,TEC,SBF1,PHLPP1,DOCK11,APBA1,ARHGEF40,TNS3,VASP,ADRBK1,RALGPS2,ANKS1B,MCF2L,RANBP1,MTMR10,EXOC8,PLEKHF1,CADPS2,MYLIP,FARP2,EPB41L5,RASGRF1,ARAP2,ARHGEF28,PLEKHA6,PHLDB3,PLEKHA7,SPATA13,SNTB1,FAM109A,RASA1,MAPK8IP1,FRMD4B,ARHGAP24,DGKH,RGPD5,SWAP70,PLEKHH2,LDLRAP1,ARAP1,APPL2,FGD6,PLD1,TBC1D4,AFAP1,ARHGEF9,DEF6,NGEF,DOCK9,ARHGEF4 |
| 4.053e-12 | -26.23 | GNF2_CENPF | MSigDB lists | GNF2_CENPF | 61 | 32 | 17758 | 2588 |
DLGAP5,HJURP,FOXM1,CKAP2,PTTG1,CDCA3,NDC80,CDCA8,FANCI,TOP2A,PCNA,CCNA2,PRC1,PLK4,SMC4,CKS2,HMMR,ZWINT,ASPM,CDC20,MYBL2,WHSC1,NUSAP1,CCNF,KIF11,CDK1,PRIM1,AURKA,CENPE,CCNB2,UBE2C,E2F8 |
| 4.069e-12 | -26.23 | transmembrane receptor protein tyrosine kinase signaling pathway | biological process | GO:0007169 | 792 | 190 | 16441 | 2455 |
MYL9,CASP3,TNK1,RET,EPHA4,NRG2,PDGFRL,PSME1,ITPR2,PDGFB,SPTB,SH3KBP1,CALM2,RPS6KA2,PSMD1,CTGF,ELMO2,SHC3,PSMC2,IL31RA,PIK3CA,PIK3CD,MYH14,TIAM1,TIPARP,RASGRP1,CASP9,PRKAR2B,AGO4,ROR1,ZFAND5,ARF4,ABR,RHEB,PGF,PLCG1,AREG,LIMK1,CAB39,HDAC1,CTNND1,MAPK13,EIF4EBP2,HSPB1,GAB1,PPP2R5D,PSMC1,MYL12B,RRAGD,PCSK5,FGD1,PRKAA2,RASA2,SOX9,PRKAA1,PSMD7,ATP6V1E2,CALM3,TEC,NCKAP1,PHLPP1,DUSP5,IGF1R,FLRT3,PAK2,PRKCI,NPTN,MAPK7,NCAM1,PSMA5,SOCS5,MAPKAPK3,CALM1,STRADB,EPHA1,ELK1,CYFIP2,PSMA4,EGFR,RASA1,CDK5R1,MAPKAPK2,TSC1,INSR,PRKAG2,PHLPP2,CSF1,NFKBIA,ITPR1,EFNA1,ARPC2,JAK3,RPS6KA3,SPRED1,SORBS1,REPS2,RPS6KA1,IQGAP1,SLC2A8,PSME2,ERBB2,RASGRP3,PRKACA,DDR1,FLT3,ARHGEF16,PDGFA,ATP6V0B,SS18,RALB,DOK4,CDKN1B,DAB2IP,EPHB4,RASGEF1A,FRS3,SULF2,AKT1,RIPK2,ERBB2IP,ITPR3,DUSP4,CBL,MYL12A,GIGYF1,SOCS3,EPHA10,IRS2,PTPRJ,FYN,IDE,JAK1,NGFRAP1,PSMD3,AXL,SLC9A6,SIPA1L1,STAT1,SPTBN5,NRG1,EFNA5,ARHGAP4,RGS14,MAPK12,PRKAR1A,ARHGEF3,TNRC6C,SORT1,MPZL1,ARHGEF11,ARHGEF7,EPS8,PSMD10,FGF19,EFNB1,NRP2,SGPL1,ADRBK1,IRAK1,PTEN,MCF2L,MAPK11,ERBB3,SPRY2,SYK,CAMK2G,RASGRF1,PDGFC,ARHGEF28,ADAM17,RHOA,PSMB4,NR4A1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,BCAR1,TXK,GPLD1,CD8A,FGFR2,FGF18,GRIN2D,ITGAV,ATP6V1C1,ARHGEF9,ARHGEF4,NGEF |
| 4.647e-12 | -26.09 | cellular component morphogenesis | biological process | GO:0032989 | 1223 | 269 | 16441 | 2455 |
CFAP74,ADD1,SSH1,AK7,CCNO,GATA3,NRG2,PSME1,PLXNA1,FAM101B,CALM2,WEE1,TGFBR3,PSMD1,DNM2,PACSIN1,TIAM1,DNAAF3,SPEF2,CASP9,LOXL2,ARHGEF26,ULK2,PLCG1,DNM1L,LIMK1,TRAF3IP1,TMOD2,UNC5B,KLF2,SCN5A,SOX9,RAB23,SLC1A3,MERTK,RAC2,FRY,FLRT3,CACNA1D,PIKFYVE,NCAM1,TTLL1,DNAI1,EPB41L5,B9D2,CEP89,CALM1,KIF20B,EPHA1,ILK,NPHP3,ANTXR1,DPYSL4,NFIB,PSMA4,RASA1,RHOB,SEMA4D,MATN2,WDR19,FAM83D,AURKA,NR4A2,EFNA1,B4GAT1,ARPC2,CFAP20,TRPC3,RPS6KA3,EHD1,MTM1,SPRED1,GRHL2,TCTN2,ST14,IQGAP1,RPS6KA1,C5orf30,BCL2L1,DACT1,DAB2IP,EPHB4,DLG3,RASGEF1A,SNX10,ETV4,SEMA3B,COL6A2,FZD4,PRKCQ,SLC11A2,ALCAM,FZD7,CEP162,EPHA10,IRS2,FYN,JAK1,SHROOM3,SLC9A6,AXL,WWTR1,NRG1,COBL,ATMIN,PRKAR1A,TTC8,FARP1,FLOT1,NES,PLPPR4,SPR,FGF19,EFNB1,SIX4,RND1,NEO1,ANK1,PTEN,BAX,CD9,ADAM15,ERCC2,ERBB3,S100A6,FARP2,RASGRF1,B3GNT2,ARHGEF28,FMN1,RAPGEF2,VAMP3,GRIN1,C1GALT1C1,RAB3IP,YES1,ABLIM2,CNTNAP1,FGFR2,NR4A3,RYK,GRIN2D,ITGAV,RGMA,MYL9,EMX1,CASP3,UGT8,AGRN,EPHA4,MPP5,PDGFB,CACNB4,SPTB,RPS6KA2,CTNNB1,LRRC6,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,CTTN,RP2,MYH14,BTBD3,RASGRP1,ATL1,SOD1,CELSR2,FOPNL,RNF165,EZR,DZIP1L,DPYSL3,MAP2,MYL12B,PSMC1,BVES,RASA2,PSMD7,CALM3,DUSP5,SSX2IP,BMP2,RB1,VASP,IGF1R,LRRN2,OCRL,COL6A1,PAK2,NTN1,WNT3A,PSMA5,DPYSL5,RGMB,STRADB,SCRIB,RANBP9,CDK5R1,EGFR,ONECUT1,PVRL2,PITPNA,AKIP1,SEMA3A,SHROOM2,JAK3,KLF7,PSME2,COL18A1,P2RX7,ERBB2,RASGRP3,ZMYND10,MICALL2,STIL,TTC21B,PDGFA,SS18,ARTN,FRYL,KIF14,SMO,BCL6,FRS3,S100A4,DAG1,MYL12A,ARHGAP35,PSMD3,SPTBN5,EFNA5,PLXND1,LIFR,COL9A3,PACSIN2,ARHGEF11,FRMD6,POC1B,ARHGEF7,LRP4,PSMD10,COL4A5,TGFBR1,ITGA2B,NRP2,GBX2,KIF5B,BMP7,SGK1,RPGR,CAMK2G,HES1,RHOA,PSMB4,CFAP46,BBS2,SPAG1,MAP1B,FGF18,SPINT2,PGRMC1,CEP41,PLOD3,L1CAM,NGEF |
| 5.112e-12 | -26.00 | developmental process | biological process | GO:0032502 | 5307 | 940 | 16441 | 2455 |
DOC2A,HECA,ADD1,AK7,RET,MCOLN3,HEXB,CACNA2D2,CCNO,NRG2,IL18,KIF26A,GRM5,TP73,NPM2,CDKN2C,CALM2,WEE1,PSMD1,TGFBR3,PAQR5,ALDH1A3,RDH14,KLF3,DNM2,CLDN4,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,TIPARP,DNAAF3,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,GINS4,LCP1,ABR,PGF,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,MYLK,HDAC1,TMOD2,RNASEL,ITPKA,LSM14B,ARF6,GAB1,E2F8,HOXC13,SCN5A,ALDH6A1,TMTC3,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,FLII,RAC2,FRY,MEGF8,FLRT3,ZIC5,NEK2,USP1,MYDGF,MAPK7,NCAM1,DGKG,MYLIP,TTLL1,PAQR7,REC8,UFD1L,SALL4,ERO1A,SHARPIN,FHL2,CALCRL,KIF20B,NPHP3,MEST,ILK,ELK1,TP53INP2,DPYSL4,PSMA4,GNA11,RHOB,PTPRF,NCOA3,ETS2,HTT,TIMM8A,SEMA4D,ITPR1,DGAT2,CLMN,AURKA,B4GAT1,GDF11,CFAP20,NDE1,DRP2,ARPC2,TRPC3,RPS6KA3,CSRP2,XDH,ADAMTS16,EGLN1,MTM1,PAPSS2,GRHL2,NQO1,LFNG,INPP5D,WDTC1,C5orf30,PKP2,PRKACA,APC2,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,MYT1,SNX10,ETV4,SSH3,CAMSAP3,COL6A2,LGALS8,FZD4,SAT1,HTATIP2,SYP,RAB38,TANC1,EBF2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,CORO1C,AXL,WFS1,SIPA1L1,WWTR1,PNPLA6,TRABD2A,RGS14,ARNT,MAPK12,TTC8,CTHRC1,TNRC6C,NKX3-1,FARP1,RBM24,MAN1A2,DCAF7,SDC4,CCM2,BIK,FLOT1,GMCL1,CTSZ,PKN1,PLPPR4,ZNF219,ETS1,GSTP1,HOXB2,SRPX2,ICAM1,SGPL1,NEO1,CTNNBIP1,CAPN2,ZFX,ANK1,PDCD10,IGSF9,IRAK1,ITGB8,CTSC,KNDC1,GPC3,CST3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,RAG1,SGCB,ITM2C,S100A6,POU6F1,ADAMTS2,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,RAB3IP,CRISPLD2,ABLIM2,TXK,CNTNAP1,PITX2,PROM1,ACVRL1,DBI,FAM3C,NR4A3,CENPE,HMGA1,ITGAV,FHL1,OSR1,USF2,SHOX2,FOXA1,PHC1,TLL2,MYL9,TNK1,EPAS1,AGRN,CUL4B,EPHA4,SUDS3,ARFGEF1,PHOSPHO1,NDRG2,F11R,PDGFB,SDC1,SPTB,SLC9A3R2,PLS3,TFAP2E,RPS6KA2,PCNA,CTNNB1,NPNT,SHC3,IL6ST,MITF,PAPSS1,PSMC2,ELF5,TMEM143,DUSP10,TNFRSF18,NTN4,NEB,THRB,MARK1,CELSR2,CITED4,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CLCN2,CDK1,RHEB,PLEKHB1,DZIP1L,DPYSL3,IRX3,HS6ST1,AGPAT2,MAP2,HOXA9,POMT1,MAFF,MYL12B,RUNX2,USH1C,LGALS3,RASA2,PSMD7,RACGAP1,CNTNAP2,NCKAP1,FBLN1,DHRS3,PGAP1,IL18R1,ANO1,SSX2IP,BMP2,TNS3,RB1,DAZAP1,VASP,TIMP1,IGF1R,GATA2,FRAS1,KIF13B,PAK2,PIM1,WNT3A,NTN1,ALDH3A2,PSMA5,CYP26B1,DPYSL5,PCDH1,RGMB,STRADB,TCF7,SCRIB,EIF2AK1,UNC45B,G2E3,PRX,SMN1,CDK5R1,FOXD2,MAPKAPK2,MOSPD3,FA2H,COL13A1,PVRL2,MFSD2A,PHLPP2,ITGA7,CSF1,PRPS2,TMEM120A,AKIP1,SEMA3A,CCNB2,CTBP1,NF2,HOXB7,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,STIL,EMP2,SDF4,PER2,IER3,TTC21B,PDGFA,TACC2,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,GYS1,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CDC20,CCSAP,PTGER4,ACO1,MYL12A,DAG1,PTGS2,DUOX1,RTN4RL1,IDE,PTPRJ,PAFAH1B3,PTK7,PSMD3,EFNA5,RPL22,LTA4H,POMGNT2,CTDSP1,BIN1,COL9A3,DYRK3,PACSIN2,CDH22,CD63,ADGRG1,CTSB,MCTP2,GABRG2,PSMD10,GDF15,JAG2,CRABP2,FZD6,PPP2R3A,NRP2,GBX2,ZDHHC21,CD109,FOXP2,CDK16,UBE2J1,TFAP2A,SGK1,HMGCL,SYK,CAMK2G,FAM134C,TLE6,GCNT1,DUSP1,HES1,RHOA,PSMB4,CRIP2,LITAF,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BBS2,PRDX4,BCL10,CNOT2,FAT4,SCG2,TWSG1,FGF18,PGRMC1,E2F1,PKD2,PPP2R3C,CFAP74,GAA,ACVR1,HSPG2,SSH1,LGR4,VANGL1,TMEM41B,CUL1,GATA3,PSME1,CAMK1D,PLXNA1,CCNB1,VASH1,SEPT4,FAM101B,CHST2,PICK1,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,POLL,PIK3CA,TACSTD2,RCAN3,ZBTB18,PACSIN1,SGCE,ACVR1C,CASP9,AURKB,LDB2,CCNF,SAV1,ZFAND5,ULK2,ARHGEF26,SFXN1,HLF,AREG,PLK2,TBX1,PTER,LRIG1,NKD1,BMP1,DHTKD1,SERPINI1,SPRY4,TANC2,UNC5B,F2RL1,LZTS1,FGD1,SEMA6B,KLF2,INPPL1,MRC2,CDKN1C,SLC25A27,NOTCH2,SLC1A3,HERC6,APBA1,TNFRSF19,KIAA1161,MECOM,MESDC2,CALR,DOPEY2,ITGA3,CYR61,BHLHE41,MSH2,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,DLX4,TMED2,GPR161,RIMS2,IGSF3,DNAI1,SPATA20,EPB41L5,KLK5,MMD,B9D2,CEP89,CALM1,AMER1,DCHS1,ANO6,WHSC1,VEZT,EPHA1,KDM3A,ANTXR1,NFIB,STX3,RASA1,FAS,MMP15,WDR19,MATN2,NAB2,FAM83D,SFMBT1,PCDH19,KLK7,NR4A2,EFNA1,HOOK1,EHD1,IRF1,ELK4,FOXO6,SPRED1,TCF25,SLC2A4,TCTN2,ST14,THRA,CAST,RPS6KA1,IQGAP1,NDRG1,IRX4,BCL2L1,EGR3,DDR1,FLT3,MNS1,EPM2A,NOV,APLP2,CCNA2,DOK4,CDKN1B,CNNM4,DAB2IP,PDE4D,EPHB4,FLOT2,MED30,SEMA3B,GPX4,FOXJ2,DMTN,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CEP162,CMTM7,EPHA10,FYN,JAK1,NGFRAP1,STAT1,RAB29,NRG1,KLF5,PRR15,CBX7,COBL,ATMIN,PRKAR1A,WASF3,PCOLCE,JRKL,HAPLN3,CENPI,PBX3,NES,SEPP1,SPR,FGF19,EFNB1,TEAD3,ADGRB2,SIX4,SCML1,RND1,E2F7,OXCT1,MGAT1,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,ERCC2,TAGLN2,MAP3K7,CITED2,TTPA,GFI1,SPRY2,OSGIN1,MSH6,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,TCFL5,FURIN,VAMP3,DIAPH2,C1GALT1C1,FBXO9,YES1,FOS,GPLD1,CDK5RAP1,RGS9,TIMP3,CTNS,DGCR2,FGFR2,PRDX3,TBX18,RYK,ERAP1,SERPINB5,GRIN2D,LRRK1,GPER1,FZD5,WDR62,NCAPG2,ARSB,SLC25A38,MELK,RGMA,JARID2,EXPH5,EMX1,CASP3,UGT8,UBE2Q1,MPP5,PLAC1,CACNB4,DNER,TMC1,EPCAM,LRRC6,GRHL1,CDKL5,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,ASH2L,RP2,CTTN,MYH14,ARNT2,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,SOD1,TRIM8,ASXL1,FOPNL,RNF165,ARHGDIB,EDNRA,CXXC4,MDK,GPRC5B,HPSE,TDRD7,TRIM45,NRGN,APBA2,PPP2R5D,PSMC1,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,TEC,DUSP5,SPP1,CA2,LRRN2,FAM20C,OCRL,COL6A1,EBF4,PRKCI,SUCO,FNIP1,NPTN,C10orf54,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,HMG20B,C3orf58,RANBP9,EGFR,SOX13,FECH,GNAS,BCAR3,ONECUT1,TSC1,INSR,PLPP3,TMEM30A,UTP14C,ALPK3,PITPNA,DONSON,EGFL7,SHROOM2,JAK3,RARG,APOL2,DRD1,KLF7,PAX6,IL15,PSME2,HDAC11,SOD2,COL18A1,TDRKH,MRAS,ZMYND10,OSR2,MICALL2,PHLDA1,EXT2,MXD1,SS18,KCTD15,ARTN,SETDB2,FRYL,KIF14,SMO,RPN2,DIXDC1,TWIST1,ECE1,NFKB2,LOXL1,F2R,HSPA2,FRS3,MAP3K3,SOAT1,PTPRU,OSTM1,IGSF8,GLO1,CD40,DUSP4,ARHGAP35,SOCS3,HSF4,ALDH5A1,BFSP1,BHLHB9,STAT6,PEX2,SECTM1,TLE1,PTBP3,OVOL1,SPTBN5,PLXND1,LIFR,ANXA3,SORT1,ARHGEF11,POC1B,FRMD6,ARHGEF7,CIT,LRP4,TGFBR1,COL4A5,AES,ITGA2B,HDAC9,IRF2BPL,KIF5B,TOP2A,MDM1,ADRBK1,ADORA1,LLGL2,BMP7,MYCL,RRBP1,TOX2,KIAA0319,ACTA2,ARVCF,TRIM3,MTURN,RPGR,MYO5A,ADAM17,WNT10B,CFAP46,NR4A1,ASPM,RC3H2,MBNL3,TTC7A,RUNX3,FAM73B,NDRG3,FOXL1,LEPR,SPAG1,MAP1B,ARHGAP24,LEMD2,CD8A,SWAP70,PRCP,DHRS2,CTSV,SPINT2,RAP2C,CSGALNACT1,ARRB1,HOXB13,CEP41,PLOD3,SOX8,ZMIZ1,L1CAM,AHR,NGEF |
| 5.155e-12 | -25.99 | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | 210 | 70 | 17758 | 2588 |
LMO7,MTM1,NDRG1,CCNL1,SLC20A1,PHLDA1,PER2,IER3,APOBEC3B,WEE1,ARHGAP42,FOSB,KLF3,CLDN4,TACSTD2,NFKB2,TIPARP,BTBD3,IL1RAP,MBP,CD55,KIAA0040,C3orf52,CASP9,EZR,KLK6,GALNT7,PPP1R14C,SOCS3,PTGS2,PLK2,NFKBIZ,NRG1,F2RL1,COBL,MAFF,MACC1,RASA2,FRMD6,ETS1,DUSP5,ELF3,IRF2BPL,OTUD1,IGF1R,FAM84B,NCEH1,DUSP1,HES1,TGIF1,NR4A1,RAPGEF2,PLAUR,CRIP2,ANO6,FNDC3A,FOS,FRMD4B,SERTAD2,ETS2,RND3,NR4A3,SH3BP4,NR4A2,GEM,SEMA3A,CPEB2,TOB1,OCLN,FOXA1 |
| 5.276e-12 | -25.97 | regulation of apoptotic process | biological process | GO:0042981 | 1404 | 301 | 16441 | 2455 |
ACVR1,TRIM24,GRIK2,TSC22D3,FAM129B,DNAJC3,RET,XIAP,GATA3,PSME1,CAMK1D,SEPT4,BARD1,CARD10,TP73,DAPK2,PAK6,PSMD1,CTGF,ALDH1A3,IL31RA,PIK3CA,DNM2,PPP1CA,TIAM1,ANKRD9,NEK4,ACVR1C,CASP9,BNIP3L,AURKB,SAV1,SLC25A5,POR,ARF4,ABR,DNM1L,PLK2,TBX1,PPP2R4,NOD2,MAP3K11,HDAC1,UNC5B,HSPB1,TRAF5,FGD1,ITGA6,SOX9,PRKAA1,SLC25A27,NOTCH2,MERTK,LMNA,TFAP4,CALR,CYR61,MSH2,DAPK1,MAP3K9,TNFRSF12A,MYDGF,MAPK7,ANO6,FHL2,ILK,PSMA4,FBXO10,RHOB,RASA1,FAS,STK17A,HTT,SEMA4D,AURKA,NR4A2,STK39,GDF11,MAP3K5,RPS6KA3,XDH,DMPK,NQO1,THRA,INPP5D,RPS6KA1,CAST,BCL2L1,CD274,EGR3,AIFM2,FLT3,SP100,CDKN1B,DAB2IP,LGMN,CDKN2D,TMBIM1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CBL,IRS2,FYN,CDK19,NGFRAP1,STK26,WFS1,AXL,STAT1,NRG1,AREL1,ARHGEF3,HSP90B1,NKX3-1,TAOK2,TRAF2,BIK,PDIA3,NES,ETS1,GSTP1,BEX2,ICAM1,SIX4,PDCD10,IRAK1,CTSC,PTEN,MCF2L,SGK3,BAX,PLEKHF1,TMBIM6,ERBB3,CITED2,MAP3K7,RAG1,ITM2C,SPRY2,OSGIN1,RAPGEF2,PIK3R1,GRIN1,PIM3,GPLD1,BTG1,KIAA0141,FGFR2,PRDX3,NR4A3,ITGAV,GPER1,OSR1,MELK,CASP3,TRIM2,AGRN,SUDS3,ERP29,EPCAM,RPS6KA2,CTNNB1,P4HB,IL6ST,SIVA1,PSMC2,MITF,TNFRSF18,ARNT2,CTTN,SLC39A10,CYP1B1,PLK1,SOD1,KCNIP3,ITCH,PRKRA,STK17B,CDK1,VCP,OPTN,MDK,MADD,KLF11,PSMC1,PRKAA2,BMF,LGALS3,PSMD7,PHLPP1,ADAMTSL4,BMP2,IGF1R,TIMP1,PAK2,PRKCI,FNIP1,PIM1,WNT3A,PSMA5,OXR1,STRADB,SCRIB,IFIT3,BCL2L13,EGFR,CDK5R1,G2E3,NFKBIA,JAK3,IFI6,RARG,PSME2,TP53,SOD2,P2RX7,ERBB2,COL18A1,STIL,PHLDA1,BCAP31,ARHGEF16,IER3,SRPX,KIF14,SMO,BCL6,TWIST1,STEAP3,APIP,EGLN3,F2R,CTH,PPIF,SIRT1,BAG4,AKT1,FIGNL1,GLO1,CD40,MAP3K6,CASP4,SOCS3,PTGS2,BHLHB9,PSMD3,TLE1,IRF7,ARHGAP4,LIFR,CBX4,ZC3HC1,FAM134B,BIN1,GCLM,PINK1,CPEB4,ARHGEF11,CTSB,ARHGEF7,DAP,SERPINB9,PSMD10,SELL,GDF15,AES,TGFBR1,TOP2A,CARD8,ADORA1,BMP7,TFAP2A,SGK1,BUB1,FAIM,DUSP1,RHOA,ADAM17,HMGN5,WNT10B,PSMB4,PLAUR,GCLC,RGCC,TRIM35,PELI3,BCAR1,MAPK8IP1,BCL10,CASP7,SCG2,DHRS2,E2F1,ARRB1,SOX8,ARHGEF9,HIPK3,ARHGEF4,NGEF |
| 5.357e-12 | -25.95 | GNF2_SMC2L1 | MSigDB lists | GNF2_SMC2L1 | 32 | 22 | 17758 | 2588 |
HMMR,ZWINT,FOXM1,ASPM,CDC20,NDC80,MYBL2,CDCA8,NUSAP1,KIF11,CDK1,PRIM1,TOP2A,CCNA2,PCNA,CKS1B,BUB1,CENPE,CCNB2,ESPL1,SMC4,CKS2 |
| 5.547e-12 | -25.92 | LEE_EARLY_T_LYMPHOCYTE_UP | MSigDB lists | LEE_EARLY_T_LYMPHOCYTE_UP | 100 | 43 | 17758 | 2588 |
CD99,CEP70,DLGAP5,TUBB4B,PTTG1,CDCA3,NDC80,NUF2,KIF2C,CCNB1,FANCI,TOP2A,E2F7,UBE2T,KIF14,PRC1,NEK2,BUB1,FAIM,RAG1,GFI1,SYK,CKS2,HMMR,CXXC5,CENPA,KIF20A,ASPM,MPP1,PBK,WHSC1,GGH,CDCA2,NUSAP1,GALNT7,KIF11,CDK1,NEIL3,AURKA,UBE2C,CCNB2,E2F8,MELK |
| 6.472e-12 | -25.76 | BLUM_RESPONSE_TO_SALIRASIB_DN | MSigDB lists | BLUM_RESPONSE_TO_SALIRASIB_DN | 335 | 97 | 17758 | 2588 |
CCNE2,TUBB4B,PTTG1,NDC80,KIF2C,SDC1,STIL,BARD1,LTBP3,PLS3,CDKN2C,PCNA,CCNA2,FOSB,PLK4,TUBG1,KIF22,RGS5,RNASEH2A,TECR,F2R,HSPA2,CKS2,CYP1B1,PLK1,CENPA,SLC39A8,PBK,CDC20,NUSAP1,AURKB,CCNF,H2AFV,CDC25C,CDK1,SGPP1,PRIM1,DPYSL3,PIAS3,CARHSP1,PAFAH1B3,BFSP1,MYLK,WWTR1,HDAC1,KPNA2,HSPB1,PACSIN2,SOX9,KIF23,ISYNA1,GPSM2,CRABP2,TSPAN7,LMNA,TOP2A,TNS3,RANBP1,MSH2,NEK2,OPN3,PRC1,H2AFY,USP1,BUB1,RFX5,MSH6,MCCC2,SMC4,HMMR,ZWINT,SHMT1,KIF20A,PRSS23,CRIP2,DBR1,MYBL2,HMG20B,KIF20B,MEST,FOS,KIF11,CYB5A,DDX23,DGCR2,TWSG1,PRDX3,PLOD2,DCK,MATN2,E2F1,AURKA,NR4A2,CCNB2,UBE2C,ESPL1,ZBTB33 |
| 6.668e-12 | -25.73 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | 1192 | 258 | 17758 | 2588 |
SSH1,MRPS15,GRIK2,GATA3,DHX8,CUL1,CCNB1,SLC20A1,BARD1,CENPN,WEE1,PSMD1,UBE2T,OSBPL3,PAQR5,STEAP2,TUBG1,HYLS1,ANKRD9,METAP2,NEK4,CDYL,NBPF3,TNS1,AURKB,ICMT,LDB2,CCNF,GINS4,PRIM1,KDSR,GDE1,E2F8,NXT2,DLAT,TMTC3,PRKAA1,RAB23,KIF23,ZNRF3,SLC1A3,GPSM2,RALGPS2,RANBP1,NEK2,MSH2,USP1,KCTD3,C9orf72,NUP85,TMED2,GFPT1,DDB2,MYBL2,WHSC1,PLS1,KIF20B,DCP2,CYB5A,FAS,PTPRF,SLCO4A1,FNTA,FAM64A,MTFMT,ETS2,DCK,C1orf21,FAM83D,PIAS2,AURKA,ARPC2,HOOK1,DLGAP5,PTTG1,ETNK1,PKP2,NUF2,RNF182,FAM91A1,TMEM19,NUDT12,CDS1,RNASEH2A,ACSL4,CDKN2AIP,NUSAP1,CDCA2,PKMYT1,ITPR3,GTF2A2,XRCC6BP1,ACYP1,SIPA1L1,GEN1,ISOC1,MZT1,DEPDC1,CKAP2,ESRP1,ARL4C,CDCA3,GMCL1,CKAP5,AKIRIN1,FAM111A,C16orf59,E2F7,OXCT1,CTSC,CENPJ,ALG13,FJX1,PRC1,WWP1,MAP3K7,MSH6,TMX1,SMC4,ZWINT,SHMT1,PLSCR1,TACC1,CXorf57,DBR1,VAMP3,C2orf69,RAB3IP,KIF11,SKA1,TIMP3,PROM1,PRDX3,AMMECR1,NCAPG2,ESPL1,MELK,ACOT7,CCNC,KIAA1462,FAM199X,SUDS3,NDC80,MPP5,KIF2C,FANCI,HSF2,PCNA,PASK,CEP78,NTN4,MYBL1,IL1RAP,PLK1,PCGF5,CENPA,HN1L,STAU2,CKAP2L,ROR1,EAF2,ANLN,CDK1,RHEB,PI4K2B,HS6ST1,CDCA4,ZNF367,KPNA2,RAP1GAP,PPP2R5D,PPP1R2,HJURP,RACGAP1,CNTNAP2,SSX2IP,BMP2,KIAA0895,KIF13B,PAK2,SRP54,KNTC1,MPHOSPH9,DPYSL5,USP31,SPATA13,RANBP9,STEAP1,C3orf58,G2E3,MUM1L1,UAP1,PHLPP2,OTUD6B,CDCA5,PRPS2,DCUN1D1,DONSON,CCNB2,NIPA1,CCNE2,PAX6,SPC25,FOXM1,PCBP1,EMP2,KCTD9,RAD23A,PER2,SS18,KIF14,LMO4,BCL6,PLK4,SRR,GOT1,APIP,FAR1,SEPHS1,CTH,SOAT1,PPIF,CPD,TAF5,FIGNL1,CDC20,CDC25C,PEX2,C1orf43,AKNA,PPP2R2D,CMAS,DYRK3,KLHL13,POC1B,CDCA8,ERCC6L,PSMD10,SIRPA,KIF5B,TOP2A,TOX2,GTF2F2,BUB1,IQGAP3,HMMR,PHF20L1,HMGN5,ASPM,PLAUR,CCDC34,POLD3,LEMD2,NEIL3,NMI,NETO2,PGRMC1,E2F1 |
| 7.059e-12 | -25.68 | locomotion | biological process | GO:0040011 | 1396 | 299 | 16441 | 2455 |
LAMP1,ACVR1,HEXB,RET,NRG2,GATA3,PSME1,PLXNA1,CMTM6,CALM2,PAK6,TYMP,PSMD1,TGFBR3,CTGF,ELMO2,DNAH6,PIK3CA,SEMA3G,PIK3CD,TIAM1,TNS1,LOXL2,ZFAND5,ARF4,LCP1,PLCG1,LIMK1,TBX1,UNC5B,F2RL1,SEMA6B,SCN5A,ITGA6,S100A2,MERTK,RAC2,ITGA3,CYR61,MEGF8,FLRT3,PRKG1,TNFRSF12A,CACNA1D,NCAM1,NUP85,DNAI1,EPB41L5,CALM1,ANO6,EPHA1,ILK,DPYSL4,PSMA4,NFIB,RHOB,RASA1,PTPRF,SCARB2,SEMA4D,MATN2,FAM83D,NR4A2,EFNA1,B4GAT1,NDE1,ARPC2,TRPC3,RPS6KA3,SPRED1,INPP5D,RPS6KA1,RALBP1,EGR3,DDR1,APC2,CD46,NOV,DAB2IP,PDE4D,EPHB4,TSPAN1,RASGEF1A,DLG3,ETV4,SEMA3B,DOCK4,COL6A2,FZD4,SYNE2,PRKCQ,ATP1B1,ALCAM,CMTM7,EPHA10,IRS2,FYN,JAK1,CORO1C,AXL,STAT1,NRG1,CTHRC1,TAOK2,EPS8,SDC4,PLD2,PKN1,ETS1,DNAH3,SRPX2,EFNB1,FGF19,ICAM1,SIX4,WWP2,RND1,NEO1,SGPL1,CXCL16,ANK1,PDCD10,PTEN,FUT8,BAX,WWP1,ERBB3,PARP9,FARP2,PVRL4,RASGRF1,ARHGEF28,B3GNT2,RAPGEF2,PIK3R1,GRIN1,YES1,ABLIM2,GPLD1,CNTNAP1,PITX2,BTG1,FGFR2,ACVRL1,NR4A3,RYK,GRIN2D,ITGAV,ARSB,CD81,RGMA,MYL9,TNK1,AGRN,EPHA4,F11R,CACNB4,DNER,SDC1,PDGFB,SPTB,SH3KBP1,RPS6KA2,LRRC6,CTNNB1,CDKL5,SHC3,DPYSL2,SIVA1,PSMC2,MITF,DLG1,TRPC1,NTN4,MYH14,CTTN,RASGRP1,CYP1B1,CD55,MARK1,CELSR2,STRIP2,ITCH,RNF165,EZR,CR2,ANLN,CDK1,DPYSL3,MDK,MYL12B,PSMC1,LGALS3,BVES,RASA2,PSMD7,CALM3,NCKAP1,DUSP5,CORO1B,SPP1,TNS3,VASP,GATA2,COL6A1,PAK2,PRKCI,BRAT1,WNT3A,NTN1,ZRANB1,PSMA5,CCDC88A,DPYSL5,PODXL2,RGMB,SPATA13,STRADB,SCRIB,RANBP9,EGFR,CDK5R1,PVRL2,PLPP3,ITGA7,PITPNA,PLD1,ATP1B3,SHROOM2,JAK3,SEMA3A,DRD1,KLF7,PSME2,ERBB2,RASGRP3,EMP2,ARHGEF16,PDGFA,ARTN,LHX6,SMO,TWIST1,DIXDC1,SCYL3,FRS3,DAG1,MYL12A,ARHGAP35,IDE,PTPRJ,PTK7,PSMD3,PEX2,RCAN2,SPTBN5,EFNA5,PLXND1,POMGNT2,CMTM4,COL9A3,ARHGEF11,ADGRG1,CD63,CTSB,ARHGEF7,PSMD10,SELL,COL4A5,TGFBR1,SIRPA,NRP2,ITGA2B,XPR1,GBX2,KIF5B,ADRBK1,BMP7,KIAA0319,SYK,MYO5A,CAMK2G,GCNT1,HES1,RHOA,ADAM17,PSMB4,CFAP46,PLAUR,NR4A1,ASPM,BCAR1,ARHGAP24,SCG2,FGF18,PGRMC1,SOX8,L1CAM,NGEF |
| 7.259e-12 | -25.65 | regulation of phosphorus metabolic process | biological process | GO:0051174 | 1682 | 349 | 16441 | 2455 |
TXN,PPP4R4,ACVR1,IBTK,GRIK2,TRIM5,DNAJC3,NRG2,PSME1,IL18,CCNB1,SNX9,BARD1,CARD10,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,CTGF,RGS3,IL31RA,PIK3CA,CRY2,NEK4,TNIP1,PBK,CDA,PRKAR2B,PPP1R14C,ENPP1,PLCG1,CAMK2N2,DNM1L,AREG,ANKRD6,TBX1,TRAF3IP1,PPP2R4,NOD2,MAP3K11,SPRY4,HSPB1,F2RL1,PDPR,GAB1,DLAT,CDKN1C,NUAK1,ITGA6,SOX9,PRKAA1,SH3RF2,MECOM,TFAP4,RAC2,CYR61,FBXO7,MAP3K9,SORL1,MYDGF,NCAM1,MAPK7,PPP6R1,GPR161,SOCS5,MMD,MAPKAPK3,CALM1,KCTD20,CALCRL,EPHA1,NPHP3,ILK,PSMA4,RASA1,FAS,PRKAG2,HTT,SEMA4D,PELI2,FAM83D,STK39,EFNA1,GDF11,MAP3K5,XDH,EGLN1,SPRED1,IQGAP1,PRKACA,FLT3,CCND1,APLP2,ST5,CCNA2,RALB,DACT1,CDKN1B,DAB2IP,PDE4D,DLG3,RASGEF1A,CDKN2D,CAMSAP3,PSRC1,RIPK2,NRBF2,FZD4,PFKFB2,DMTN,COX11,CDCA2,RAD17,PKMYT1,FZD7,IRS2,FYN,JAK1,CCNB3,PPP2R5A,STK26,CORO1C,WFS1,WWTR1,KIAA1804,SLC27A1,NRG1,RGS14,ARNT,PRKAR1A,FARP1,HSP90B1,NKX3-1,TAOK2,TRAF2,SDC4,FLOT1,HERC5,PKN1,GSTP1,SRPX2,TIPRL,FGF19,ICAM1,DIRAS3,PDCD10,IRAK1,PTEN,KNDC1,BAX,MAPK11,ERBB3,MAP3K7,SPRY2,RASGRF1,PDGFC,RAPGEF2,PIK3R1,GRIN1,YES1,GPLD1,CDK5RAP1,FGFR2,PRDX3,ACVRL1,RYK,GRIN2D,GPER1,CENPE,LRRK1,FZD5,CD81,CCNC,CASP3,CAMKK1,EPHA4,NDRG2,NENF,PDGFB,ERP29,SPTB,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,DLG1,DUSP10,TNFRSF18,SLC39A10,RASGRP1,PLK1,SOD1,ITCH,EZR,IDH1,CDK1,VCP,EDNRA,KDM4D,GPRC5B,MADD,PRKCDBP,CAB39,PSMC1,PPP2R5D,PRKAA2,PIFO,LMTK3,PPP1R2,PPP1R12A,RASA2,UBASH3B,PSMD7,CALM3,SORBS3,TEC,PHLPP1,FBLN1,DUSP5,BMP2,RB1,IGF1R,FAM20C,PAK2,FNIP1,BRAT1,MDFIC,NPTN,PIM1,WNT3A,PSMA5,CCDC88A,MDFI,STRADB,PDE5A,EIF2AK1,PDK3,RANBP9,EGFR,CDK5R1,FECH,GNAS,BCAR3,MAPKAPK2,TSC1,INSR,PLPP3,CSF1,NLRC5,JAK3,PROM2,DRD1,CCNE2,AVPI1,NF2,IL15,FOXM1,PSME2,CTDSPL,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,EMP2,STIL,SYTL2,IER3,PDGFA,PPME1,KIF14,TWIST1,APIP,F2R,CTDSP2,HSPA2,DVL2,FRS3,CHP1,CKS2,MAP3K3,PPIF,SIRT1,TIMP2,BAG4,AKT1,DUSP4,CD40,CDC25C,PDHX,MAP3K6,DAG1,C3orf33,SOCS3,DNAJC10,PTPRJ,RBL1,STK38,PSMD3,SPTBN5,EFNA5,PPP2R2D,ABCA1,CNEP1R1,CTDSP1,ARFGEF3,PINK1,TAB3,LRP4,GNAL,PSMD10,TGFBR1,GDF15,TRIB2,PPP2R3A,SH2D4A,CD109,ADORA1,BMP7,CKS1B,H2AFY,HEXIM2,IQGAP3,SYK,CAMK2G,DUSP1,HES1,ADAM17,RHOA,PSMB4,PLAUR,RGCC,PPARA,MAPK8IP1,BCL10,LEMD2,BANK1,SWAP70,RAP2C,FGF18,ARRB1,PPP2R3C,PKD2,UBE2C,HIPK3,PKIA |
| 7.493e-12 | -25.62 | regulation of phosphorylation | biological process | GO:0042325 | 1425 | 304 | 16441 | 2455 |
TXN,ACVR1,IBTK,GRIK2,TRIM5,DNAJC3,NRG2,PSME1,IL18,CCNB1,SNX9,BARD1,CARD10,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,CTGF,RGS3,IL31RA,PIK3CA,NEK4,TNIP1,PBK,PRKAR2B,PPP1R14C,ENPP1,PLCG1,CAMK2N2,AREG,ANKRD6,TBX1,TRAF3IP1,NOD2,MAP3K11,SPRY4,HSPB1,F2RL1,GAB1,CDKN1C,ITGA6,SOX9,PRKAA1,MECOM,TFAP4,RAC2,CYR61,FBXO7,MAP3K9,SORL1,MYDGF,NCAM1,SOCS5,MMD,MAPKAPK3,CALM1,KCTD20,EPHA1,ILK,PSMA4,RASA1,FAS,PRKAG2,SEMA4D,PELI2,FAM83D,STK39,EFNA1,GDF11,MAP3K5,XDH,SPRED1,IQGAP1,PRKACA,FLT3,CCND1,APLP2,ST5,CCNA2,RALB,DACT1,CDKN1B,DAB2IP,PDE4D,RASGEF1A,CDKN2D,PSRC1,RIPK2,NRBF2,FZD4,PFKFB2,DMTN,COX11,RAD17,PKMYT1,FZD7,IRS2,FYN,JAK1,PPP2R5A,CCNB3,STK26,CORO1C,WWTR1,KIAA1804,SLC27A1,NRG1,RGS14,ARNT,PRKAR1A,NKX3-1,TAOK2,TRAF2,SDC4,FLOT1,HERC5,PKN1,GSTP1,SRPX2,FGF19,ICAM1,DIRAS3,PDCD10,IRAK1,PTEN,KNDC1,BAX,MAPK11,ERBB3,MAP3K7,SPRY2,RASGRF1,PDGFC,RAPGEF2,PIK3R1,GRIN1,YES1,CDK5RAP1,FGFR2,PRDX3,ACVRL1,RYK,GRIN2D,GPER1,CENPE,LRRK1,FZD5,CD81,CCNC,CASP3,CAMKK1,EPHA4,NDRG2,NENF,ERP29,PDGFB,SPTB,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,DLG1,DUSP10,TNFRSF18,RASGRP1,PLK1,SOD1,ITCH,EZR,CDK1,VCP,KDM4D,GPRC5B,MADD,PRKCDBP,CAB39,PSMC1,PRKAA2,PIFO,RASA2,UBASH3B,PSMD7,CALM3,SORBS3,TEC,PHLPP1,FBLN1,DUSP5,BMP2,RB1,IGF1R,PAK2,FNIP1,BRAT1,MDFIC,NPTN,PIM1,WNT3A,PSMA5,CCDC88A,MDFI,STRADB,PDE5A,EIF2AK1,RANBP9,EGFR,CDK5R1,FECH,BCAR3,MAPKAPK2,TSC1,INSR,PLPP3,CSF1,NLRC5,JAK3,PROM2,DRD1,CCNE2,AVPI1,NF2,IL15,FOXM1,PSME2,CTDSPL,TP53,P2RX7,ERBB2,RASGRP3,CCNL1,STIL,EMP2,IER3,PDGFA,KIF14,TWIST1,APIP,F2R,CTDSP2,HSPA2,DVL2,FRS3,CHP1,CKS2,MAP3K3,PPIF,SIRT1,BAG4,TIMP2,AKT1,DUSP4,CD40,CDC25C,MAP3K6,DAG1,C3orf33,SOCS3,DNAJC10,PTPRJ,RBL1,STK38,PSMD3,SPTBN5,EFNA5,CTDSP1,PINK1,TAB3,LRP4,PSMD10,GDF15,TGFBR1,TRIB2,CD109,ADORA1,BMP7,CKS1B,H2AFY,HEXIM2,IQGAP3,SYK,CAMK2G,DUSP1,HES1,RHOA,ADAM17,PSMB4,PLAUR,RGCC,PPARA,MAPK8IP1,BCL10,LEMD2,BANK1,RAP2C,FGF18,ARRB1,PPP2R3C,PKD2,UBE2C,HIPK3,PKIA |
| 7.920e-12 | -25.56 | endometrioid_carcinoma | COSMIC cancer mutations | endometrioid_carcinoma | 16536 | 2481 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,PAQR7,HPS3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,IFT27,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,LBR,AIP,IL22RA1,VPS26A,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,LMAN2L,DDHD2,DUSP10,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 7.968e-12 | -25.56 | pancreas-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-ductal_carcinoma | 16389 | 2464 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,FAM84B,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,IL22RA1,VPS26A,PARM1,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,CAPN12,REPS2,GPR107,DLGAP5,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,ZIC5,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 8.409e-12 | -25.50 | chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | chromophobe_renal_cell_carcinoma | 440 | 118 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,FLT3,DDR1,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,PLK4,EPHB4,SCYL3,STK35,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,MAP3K6,ADRBK2,STK17B,ULK2,EPHA10,FYN,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MYLK,KIAA1804,MAP3K11,MAPK13,RNASEL,MLKL,MAPK12,PRKAA2,PINK1,DYRK3,TAOK2,CDK17,PRKAA1,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,IGF1R,IRAK1,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,PRKCI,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MAPK7,MAP3K7,SYK,PHKG2,CAMK2G,CASK,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,EGFR,TXK,STK17A,MAPKAPK2,INSR,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,RPS6KA3,MELK,DMPK |
| 8.409e-12 | -25.50 | kidney-carcinoma-chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-chromophobe_renal_cell_carcinoma | 440 | 118 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,FLT3,DDR1,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,PLK4,EPHB4,SCYL3,STK35,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,MAP3K6,ADRBK2,STK17B,ULK2,EPHA10,FYN,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MYLK,KIAA1804,MAP3K11,MAPK13,RNASEL,MLKL,MAPK12,PRKAA2,PINK1,DYRK3,TAOK2,CDK17,PRKAA1,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,IGF1R,IRAK1,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,PRKCI,MAP3K9,ADCK2,PRKG1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MAPK7,MAP3K7,SYK,PHKG2,CAMK2G,CASK,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,YES1,PDIK1L,EGFR,TXK,STK17A,MAPKAPK2,INSR,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,RPS6KA3,MELK,DMPK |
| 8.423e-12 | -25.50 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | 128 | 50 | 17758 | 2588 |
CCNE2,RMND5A,DYRK3,KIAA1462,PPP1R2,CDKN1C,FOXM1,NDRG1,CTDSPL,PTTG1,NDC80,KIF2C,CCNB1,SEPP1,EMP2,DUSP5,LBR,TOP2A,ADD3,CCNA2,CYP1A1,REEP1,CKS1B,BUB1,IGFBP2,BTBD3,SMAGP,SMC4,TUBA4A,LAMP3,OLFML2A,PLK1,MYBL2,CALCRL,PYGL,AURKB,LDB2,KIF11,CDK1,TIMP3,PDLIM3,GPRC5B,TBX1,RAB31,MAOA,UNC5B,UBE2C,CCNB2,GAB1,CSRP2 |
| 8.678e-12 | -25.47 | negative regulation of cellular process | biological process | GO:0048523 | 4068 | 743 | 16441 | 2455 |
HECA,ACACB,TRIM24,ADD1,IBTK,GRIK2,TRIM5,DNAJC3,XIAP,FBXO2,IL18,MORF4L2,SYTL4,BARD1,KIF26A,PHF1,GRM5,TP73,CALM2,CDKN2C,PSMD1,RGS12,TGFBR3,CABP1,DNM2,CRY2,SEMA3G,PPP1CA,ANKRD9,APOBEC3G,SMARCA2,TNIP1,UXT,CDA,TFAP2C,PRKAR2B,LOXL2,PNKD,ARF4,ABR,PIAS3,ENPP1,MID1IP1,CAMK2N2,GRID2IP,ANKRD6,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,TMOD2,RNASEL,ARF6,HSPB1,E2F8,NFKBIE,NUAK1,ITGA6,SOX9,RAB23,ZNRF3,FAM21C,MERTK,LMNA,ELF3,TFAP4,PAIP2B,FBXO7,NEK2,MYDGF,MAPK7,SALL4,ERO1A,FHL2,KIF20B,NPHP3,ILK,PSMA4,RHOB,PLIN5,NCOA3,ETS2,HTT,SEMA4D,ITPR1,AURKA,CLMN,STK39,GDF11,CBX5,SERPINB1,RPS6KA3,XDH,EGLN1,GRHL2,LFNG,INPP5D,PTTG1,WDTC1,RGS20,PKP2,PRKACA,APC2,CCND1,CDH1,SP100,DACT1,TAX1BP3,DLG3,CDKN2D,ETV4,RNF169,MX1,CAMSAP3,PSRC1,RIPK2,APOBEC3D,FZD4,VPS4B,HTATIP2,SNX12,NFIX,IRS2,PEX5,CORO1C,WFS1,AXL,WWTR1,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,TCAF1,FARP1,TNRC6C,NKX3-1,HSP90B1,CKAP2,TRAF2,ANO9,PKN1,ZNF219,ETS1,GSTP1,TIPRL,ICAM1,NEO1,CTNNBIP1,PDCD10,IRAK1,GPC3,CST3,BAX,ADAM15,TMBIM6,WWP1,MAPK11,RAG1,ITM2C,CRTAP,PLSCR1,RAPGEF2,PIK3R1,GRIN1,EMP3,PIM3,PITX2,BTG1,NR1D2,ACVRL1,NR4A3,ITGAV,HMGA1,FHL1,OSR1,SHOX2,SRSF9,FOXA1,SIGIRR,TNK1,CNOT8,EPHA4,SUDS3,ARFGEF1,LMCD1,NDRG2,TP53I11,HDAC6,PDGFB,SPTB,FANCI,SUSD2,BTG3,RPS6KA2,CTNNB1,IL6ST,PSMC2,MITF,ELF5,PASK,DUSP10,TNFRSF18,RGS5,PLK1,THRB,CD55,KCNIP3,ING1,CBX6,EZR,TNFAIP8L1,EAF2,PRKRA,SESN1,CDK1,RHEB,OPTN,IRX3,DPYSL3,TRIM9,KLF12,HOXA9,RAB11FIP1,PRKCDBP,CTNND1,KLF11,RRAGD,PRKAA2,RUNX2,BMF,LMTK3,LGALS3,DNAJB2,UBASH3B,RASA2,PDCL,PSMD7,SORBS3,HES2,FBLN1,DHRS3,CORO1B,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,TBCD,MDFIC,PIM1,NTN1,WNT3A,PSMA5,CYP26B1,STRADB,SCRIB,EIF2AK1,IFIT3,G2E3,CDK5R1,NLRC5,CDAN1,SEMA3A,IFI6,CTBP1,NF2,FOXM1,P3H2,CTDSPL,TP53,P2RX7,ERBB2,BAHD1,STIL,CYP26A1,SYTL2,PER2,IER3,PDGFA,SRPX,LMO4,PLCG2,BCL6,VAT1,ESPN,NOTCH3,OAS3,CTDSP2,DVL2,SULF2,CTH,SIRT1,PPIF,TIMP2,ERLEC1,AKT1,FIGNL1,CDC20,SERTAD3,PTGER4,C3orf33,DAG1,MYPOP,PTGS2,DNAJC10,PTPRJ,ATP1A1,IDE,RBL1,PSMD3,STK38,CHMP4B,IRF7,ARHGAP4,ZC3HC1,FAM134B,ARFGEF3,CTDSP1,PINK1,PACSIN2,CPEB4,ADGRG1,DAP,CTSB,PSMD10,NKRF,FZD6,SH2D4A,PPP2R3A,CD109,FOXP2,TFAP2A,UBE2J1,TRIM21,BUB1,HEXIM2,KLF9,FAIM,DUSP1,NFE2L3,HES1,RHOA,HMGN5,PSMB4,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,STMN3,TRIM35,CARD19,COL7A1,PELI3,FXR2,MAPK8IP1,BCL10,PRDX4,CNOT2,BANK1,SERPINA1,TWSG1,SCG2,NMI,E2F1,PKD2,NDFIP1,UBE2C,TBC1D4,PTGES,HIPK3,ZBTB33,PKIA,TXN,PPP4R4,ACVR1,LGR4,TSC22D3,FAM129B,GATA3,CUL1,PSME1,CAMK1D,CCNB1,PLA2G16,VASH1,FAM101B,RIC1,PICK1,CTGF,ZFP36,RGS3,IL31RA,FOSB,PIK3CA,IRF2,TACSTD2,PACSIN1,ZBTB18,ACVR1C,PBK,CDYL,BNIP3L,SLC35C1,AGO4,PIF1,AURKB,CCNF,SAV1,SLC25A5,POR,ULK2,AHRR,SLC25A4,AREG,PLK2,TBX1,NKD1,PPP2R4,PRDM5,EIF4EBP2,SERPINI1,SPRY4,UNC5B,F2RL1,LZTS1,SEMA6B,INPPL1,CDKN1C,PRKAA1,SLC25A27,NOTCH2,SH3RF2,MECOM,CALR,ITGA3,CYR61,PIK3AP1,BHLHE41,VASN,MSH2,PRKG1,DAPK1,SORL1,DLX4,GPR161,SOCS5,EPB41L5,QSOX1,MFI2,CALM1,AMER1,WHSC1,EPHA1,KDM3A,NFIB,RASA1,FAS,AP1AR,SERTAD2,PLEKHH2,PRKAG2,NAB2,ARAP1,PIAS2,SFMBT1,NR4A2,CABIN1,EFNA1,PER3,IRF1,ELK4,SPRED1,TCF25,NLRX1,S100A11,THRA,RPS6KA1,DDIT4L,NDRG1,IQGAP1,CAST,SUZ12,FTH1,CD274,EGR3,BCL2L1,FLT3,EPM2A,ZFYVE9,APOBEC3B,CD46,APLP2,NOV,CCNA2,CDKN1B,TNPO2,DAB2IP,PDE4D,IFIT1,LGMN,NR2C1,TMBIM1,SEMA3B,CDKN2AIP,DMTN,DRAP1,COX11,PRKCQ,PKMYT1,RAD17,CBL,H2AFV,FZD7,FYN,PPP2R5A,STAT1,TRIOBP,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,AREL1,CBX7,PRKAR1A,IGFBP6,DEPDC1,EPS8,CBLL1,NES,PLD2,APOBEC3H,FGF19,SIX4,WWP2,RND1,SNTA1,E2F7,FAM111A,GNB5,RNF128,PTEN,CD9,ATP8B1,ERBB3,CITED2,MAP3K7,CNOT6L,GFI1,TTPA,TRIM62,SPRY2,MSH6,OSGIN1,NCOA2,TGIF1,CASK,ZWINT,VAMP3,FURIN,GPLD1,CDK5RAP1,RGS9,TIMP3,FGFR2,PRDX3,TBX18,SERPINB5,GPER1,LRRK1,FZD5,CPEB2,ESPL1,JARID2,CCNC,LTBP1,CASP3,ST13,CRYM,ERP29,SH3KBP1,EPCAM,TSPAN6,SIVA1,DLG1,CAPG,ARNT2,CTTN,SLC39A10,PTPRE,CYP1B1,SOD1,CXXC5,TRIM8,ASXL1,ITCH,ARHGDIB,EDNRA,CXXC4,MDK,NEIL1,MADD,CAB39,ADIPOR1,GLA,RAP1GAP,PSMC1,MIIP,ARAP3,SERPINE2,CALM3,PHLPP1,DUSP5,SPP1,PFKL,PRKCI,FNIP1,FXYD5,C10orf54,KNTC1,RFX5,ETV7,MDFI,ELK3,OXR1,HMG20B,PDE5A,NUBP1,RANBP9,EGFR,NUDT16,ONECUT1,TSC1,PLPP3,CGREF1,NFKBIA,SH3BP4,EGFL7,YOD1,SHROOM2,JAK3,TOB1,RARG,PROM2,DRD1,GAS2L1,LZTFL1,PAX6,IL15,PSME2,SOD2,COL18A1,OSR2,PATL2,MXD1,SAP130,SVBP,SETDB2,KIF14,FABP6,SMO,ZBTB49,TWIST1,DIXDC1,APIP,NFKB2,F2R,HSPA2,CHP1,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,DUSP4,ARHGAP35,SOCS3,JADE1,HSF4,BHLHB9,STAT6,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,MAD2L1BP,LIFR,ABCA1,CBX4,GLIS3,GCLM,SORT1,ARHGEF7,CIT,SERPINB9,LRP4,TGFBR1,AES,NOTUM,TRIB2,HMGXB4,HDAC9,IRF2BPL,TOP2A,SNX13,CARD8,ADORA1,TAF1B,ADRBK1,BMP7,KIAA0319,BRD7,H2AFY,KANK2,MXD3,ADAM17,WNT10B,ASPM,NR4A1,GCLC,RGCC,MBNL3,RUNX3,NDRG3,LEPR,LEMD2,ARHGAP24,SWAP70,DHRS2,CTSV,SPINT2,RAP2C,ARRB1,SOX8,AHR,CD33,ABCG1,NGEF |
| 9.129e-12 | -25.42 | SENESE_HDAC3_TARGETS_DN | MSigDB lists | SENESE_HDAC3_TARGETS_DN | 490 | 128 | 17758 | 2588 |
MYL9,BCAM,UBE2Z,PLAC1,TEX2,TGOLN2,MGAT5B,NUP62CL,BARD1,RAB15,AP1M2,CTGF,MITF,ATP13A3,SUN3,TMEM37,SCARA3,IL1RAP,KRT80,ORAI2,CXXC5,FBXL16,ASXL1,FOPNL,SERTAD4,BNIP3L,MGAM,TNS1,ARHGDIB,PPP1R14C,PTGFRN,CARHSP1,TRAM2,RAB11FIP1,EIF4EBP2,ZNF395,ZCCHC24,TMEM55B,C6orf106,FBLN1,MARCH8,TNS3,CYR61,MDFIC,LIMCH1,RIMS2,GFPT1,DCHS1,MYBL2,VEZT,ANTXR1,C11orf45,FAM64A,H1F0,NAB2,MATN2,CTBP1,GAS2L1,FOXO6,DYNLRB1,NF2,UPF3B,LFNG,PKP2,IL27RA,EXT2,MNS1,ACAP2,KIF14,ZDHHC12,ENPP5,NOTCH3,MED30,SEMA3B,SEPHS1,CTH,SNX8,MYO5B,GCA,PSRC1,UTRN,BCL7B,ALCAM,DOCK5,ALDH3B1,ALDH5A1,CDK19,WFS1,PTK7,PEX2,MAOA,PDXK,PLXND1,KDELC2,ATMIN,PCOLCE,GCAT,DCAF7,GNE,ZNF219,DSE,SLC25A43,C16orf74,ADD3,CDK16,ZDHHC13,FAH,ARAP2,RAB3B,HMGN5,OGDHL,FBXO9,STMN3,AIF1L,ENDOD1,RGS9,DGCR2,DHRS2,RIN3,FAM3C,RAP2C,CDCA7L,CENPE,SPCS3,CEP41,NDFIP1,ARSB,DIS3L |
| 9.312e-12 | -25.40 | small GTPase mediated signal transduction | biological process | GO:0007264 | 799 | 190 | 16441 | 2455 |
MYL9,KLC2,NDC80,NRG2,PSME1,KIF2C,PDGFB,CENPN,SPTB,CALM2,PAK6,RAB15,PSMD1,CTNNB1,SHC3,ARL1,PSMC2,RAB20,CTTN,MYH14,TIAM1,RASGRP1,PLK1,CENPA,ARFRP1,ARHGDIB,AURKB,RAB2B,ARF4,RHEB,ABR,LIMK1,PLK2,SH2D3C,MYLK,MAPK13,ARF6,STARD13,PSMC1,MYL12B,FGD1,ARAP3,PPP1R12A,RASA2,RAB23,PSMD7,CALM3,RACGAP1,NCKAP1,RAB6A,DOCK11,DUSP5,RAC2,RB1,RALGPS2,NOXA1,OCRL,PAK2,FAM13B,KNTC1,NCAM1,NTN1,NUP85,PSMA5,B9D2,MAPKAPK3,CALM1,STRADB,CYFIP2,PSMA4,RHOB,EGFR,RASA1,RHPN1,RASGRP2,BCAR3,MAPKAPK2,RAB31,ARAP1,RHOBTB2,PLD1,NDE1,ARPC2,JAK3,DOCK9,ARHGAP11A,SPRED1,SPC25,NF2,TRIP10,RALBP1,IQGAP1,PSME2,TP53,ERBB2,RHPN2,MRAS,NUF2,RASGRP3,KTN1,EPS8L2,ARHGEF16,PDGFA,CCNA2,CDH1,RALB,KIF14,BCL6,CDKN1B,TAX1BP3,DAB2IP,ARL4D,RAB27B,RASGEF1A,DVL2,FRS3,CHP1,DOCK4,CDC20,RAB38,DOCK5,CDC25C,ARHGAP35,IRS2,FYN,JAK1,PSMD3,PPP1CB,SPTBN5,NRG1,RAB29,ARHGAP4,SGOL1,MAPK12,ARHGEF3,ARHGEF11,ADGRG1,CENPI,ARHGEF7,CIT,EPS8,ERCC6L,ARL4C,CDCA8,PSMD10,PLD2,PKN1,SPDL1,IFT27,FGF19,SYDE2,CKAP5,RND1,DIRAS3,KNDC1,MCF2L,PRC1,BUB1,MAPK11,ERBB3,IQGAP3,NCOA2,CAMK2G,FARP2,RASGRF1,RAB3B,ZWINT,ARAP2,RHOA,CENPC,PSMB4,CTNNAL1,RAPGEF2,GRIN1,DIAPH2,SKA1,ARHGAP24,RND3,FGFR2,FGF18,RAP2C,RABL6,GRIN2D,CENPE,LRRK1,GEM,NUP37,ARHGEF9,ARHGEF4,NGEF |
| 1.010e-11 | -25.32 | phosphate-containing compound metabolic process | biological process | GO:0006796 | 1942 | 393 | 16441 | 2455 |
ACACB,ACVR1,TRIM24,SSH1,AK7,SLC25A13,PNPLA2,HEXB,RET,CUL1,NRG2,PSME1,IL18,CAMK1D,CCNB1,PLA2G16,SLC20A1,PICK1,GRM5,CALM2,DAPK2,PAK6,WEE1,TYMP,PSMD1,TGFBR3,IL31RA,PALD1,SERINC2,PIK3CA,PPP1CA,PIK3CD,NEK4,ACVR1C,PBK,AURKB,TP53I3,ULK2,SLC44A3,SGPP1,ENPP1,PLCG1,PLK2,SH2D3C,LIMK1,GNPTAB,MYLK,NOD2,MAP3K11,DHTKD1,MAPK13,RNASEL,ITPKA,GAB1,CDK17,INPPL1,NUAK1,TMEM55B,DGKQ,SOX9,PRKAA1,NDUFA4,ISYNA1,MERTK,TNFRSF19,BMP2K,ATP5H,PPP4R1,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,NCAM1,MAPK7,MAST4,DGKG,PHKG2,MCCC2,PIGC,GFPT1,PMPCB,MMD,ADCK3,MAPKAPK3,STAT4,LPGAT1,CALM1,PTPRH,PIP4K2C,PYGL,CALCRL,EPHA1,PKM,ELK1,ILK,SPTLC2,PSMA4,RASA1,PDE11A,STK17A,DGKH,PTPRF,NT5C2,PRKAG2,CSNK1G1,DCK,MPP2,DGAT2,AURKA,MDH1,STK39,SAMD8,CDK18,MAP3K5,NRBP1,RPS6KA3,XDH,DMPK,PLA2G4A,SPRED1,MTM1,DLGAP5,PAPSS2,INPP5D,RPS6KA1,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,NUDT12,MOCS1,EPM2A,CDS1,CCND1,DOK4,DAB2IP,PDE4D,EPHB4,DLG3,PHKA2,RASGEF1A,SULT2B1,GPX4,SSH3,RIPK2,PFKFB2,PTPN9,PANK1,PRKCQ,PXYLP1,ATP1B1,PKMYT1,XRCC6BP1,EPHA10,IRS2,FYN,JAK1,ACYP1,CDK19,STK26,AXL,INPP4B,KIAA1804,PNPLA6,PPP1CB,SLC27A1,NRG1,PDXK,MLKL,MAPK12,GALK1,TAOK2,CCM2,PLD2,PKN1,PLPPR4,FGF19,IRAK1,PTEN,FAM20B,SGK3,SLC44A2,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,RASGRF1,CASK,SHMT1,PLSCR1,MPP1,RAPGEF2,PIK3R1,DUSP23,GRIN1,AK4,PIM3,YES1,FOS,TXK,GPLD1,CTNS,FGFR2,ACVRL1,SLC35B3,DBI,PLA2G15,PPM1H,RYK,PGM2L1,GRIN2D,ITGAV,LRRK1,CMPK2,ACOT7,MELK,TNK1,NMRK1,PPM1J,CAMKK1,EPHA4,PHOSPHO1,CDIPT,CACNB4,PDGFB,PIGL,SPTB,INPP5E,RPS6KA2,ENTPD4,SHC3,CDKL5,IMPAD1,PAPSS1,PSMC2,PASK,SLC44A1,PAPL,DLG1,DUSP10,PTPRE,RASGRP1,STK35,PLK1,PTPN18,MARK1,ROR1,PRKRA,IDH1,CDK1,ADRBK2,STK17B,VCP,PLCH1,PI4K2B,NEIL1,FASTKD1,AGPAT2,DOLPP1,CAB39,PIK3C2B,CHPT1,PSMC1,PPP2R5D,CPPED1,PRKAA2,LMTK3,PPP1R12A,RASA2,UBASH3B,PSMD7,CALM3,ADCK5,TEC,PHLPP1,DUSP5,PGAP1,BMP2,IGF1R,PFKL,FAM20C,OCRL,PAK2,PRKCI,MDFIC,NPTN,PIM1,PLCB2,PSMA5,MDFI,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,EGFR,CDK5R1,GNAS,MAPKAPK2,NUDT16,INSR,PLPP3,PHLPP2,PRPS2,ALPK3,PLD1,JAK3,CTBP1,UGP2,IL15,PSME2,CTDSPL,DGKA,ERBB2,P2RX7,GMPR,RASGRP3,LPIN3,CDK14,PDGFA,PLCG2,PLK4,MINPP1,FAR1,F2R,CTDSP2,SCYL3,FRS3,SEPHS1,MAP3K3,AKT1,RFK,FIGNL1,PTPRU,PTGER4,DUSP4,CDC25C,PDHX,MAP3K6,PTGS2,ATP1A1,PTPRJ,ALDH5A1,ABHD12,STK38,PTK7,PSMD3,SPTBN5,ST3GAL1,CTDSP1,CDS2,PINK1,DYRK3,ENO2,TAB3,CIT,GNE,PSMD10,TGFBR1,TRIB2,SBF1,PPP2R3A,ADRBK1,CDK16,ALPP,SGK1,BUB1,IQGAP3,SYK,CAMK2G,DUSP1,PGM1,PSMB4,PLAUR,OGDHL,NADK2,RUNX3,MAPK8IP1,DGKE,PRDX4,SCG2,FGF18,HIPK3 |
| 1.049e-11 | -25.28 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | 191 | 65 | 17758 | 2588 |
AK7,NDRG1,CAMKK1,NDRG2,BCL2L1,MGST2,PATL2,SNX9,FAM46A,CASC4,TNFRSF18,RASGEF1A,NEB,SULF2,ASXL1,IGSF8,DUSP4,CBL,SESN1,CMTM7,TANC2,LTA4H,RRAGD,CPEB4,ENO2,ITGA6,UBASH3B,FRMD6,SDC4,ETV5,SELL,TGFBR1,PHLPP1,NUCB2,IL17RB,ITGB8,KLC3,TPST1,WWP1,PIM1,NTN1,EPHX1,SMC4,GFPT1,P2RX4,SYPL1,LCA5,MPP1,MBNL3,ZSCAN12,CYB5A,CD83,NCOA3,SWAP70,CDKN2AIPNL,TWSG1,TIMM8A,FAM3C,ZDHHC20,DGAT2,GRAMD1C,CD81,LRRC57,CSRP2,PHC1 |
| 1.078e-11 | -25.25 | TGCCTTA,MIR-124A | MSigDB lists | TGCCTTA,MIR-124A | 532 | 136 | 17758 | 2588 |
TMEM184B,VANGL1,EPHX4,CACNA2D2,F11R,CASC4,LMAN2L,OSBPL3,MITF,PIK3CA,SERINC2,ABCA2,TUBG1,PTPRE,MYRIP,STK35,CERS2,THRB,PCGF5,MARK1,SERTAD4,RNF11,RNF165,ICMT,ULK2,COL12A1,ABR,TRAM2,FAM177A1,LRIG1,SLC31A2,RTN3,ANXA11,NXT2,RUNX2,FRMD4A,GGA1,ZCCHC24,SOX9,RAB6A,KIAA1161,LMNA,MECOM,RAVER2,MARCH8,WDFY1,RALGPS2,OPN3,PCYOX1,LIMCH1,NPTN,MYLIP,ELK3,PRRC1,ZDHHC3,NFIB,GLCE,FA2H,CSNK1G1,ITGA7,ZDHHC20,C1orf21,YOD1,CDK18,ALG2,PLIN3,GAS2L1,ELK4,IQGAP1,RHBDL3,CTDSPL,MORC4,MAPK4,FAM78A,KCTD12,BAHD1,EMP2,MOCS1,C11orf84,TACC2,REEP1,VAT1,RASGEF1A,FLOT2,FAR1,MAP3K3,SIRT1,ERMP1,CAPN6,PTPN9,SERTAD3,RAD17,ITPR3,ALCAM,NFIX,SLC9A6,SLC27A1,PDXK,ATMIN,FARP1,MPZL1,RBM24,SLC16A14,BACE1,ARHGEF7,ZNF219,ETS1,NRP2,HMGXB4,SIX4,TMCC3,CAPN2,RNF128,RRBP1,AK3,SPRY2,IGDCC4,TACC1,NR3C1,DENND1B,PPARA,LITAF,VAMP3,DIAPH2,LRRC1,MAP1B,RGS9,CTNS,FGFR2,CCDC6,AMMECR1,NDFIP1,AHR,LRRC57,ARHGEF4,ESYT2 |
| 1.081e-11 | -25.25 | single-organism developmental process | biological process | GO:0044767 | 5226 | 925 | 16441 | 2455 |
DOC2A,HECA,ADD1,AK7,RET,MCOLN3,HEXB,CACNA2D2,CCNO,NRG2,IL18,KIF26A,GRM5,TP73,NPM2,CDKN2C,CALM2,WEE1,PSMD1,TGFBR3,PAQR5,ALDH1A3,RDH14,KLF3,DNM2,CLDN4,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,TIPARP,DNAAF3,SMARCA2,SPEF2,TFAP2C,LOXL2,ICMT,ARF4,COL12A1,GINS4,LCP1,ABR,PGF,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,MYLK,HDAC1,TMOD2,RNASEL,ITPKA,LSM14B,ARF6,GAB1,E2F8,HOXC13,SCN5A,ALDH6A1,TMTC3,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,ELF3,FLII,RAC2,FRY,MEGF8,FLRT3,ZIC5,NEK2,USP1,MYDGF,MAPK7,NCAM1,DGKG,MYLIP,TTLL1,PAQR7,REC8,UFD1L,SALL4,ERO1A,SHARPIN,FHL2,CALCRL,KIF20B,NPHP3,ILK,ELK1,TP53INP2,DPYSL4,PSMA4,GNA11,RHOB,PTPRF,NCOA3,ETS2,HTT,TIMM8A,SEMA4D,ITPR1,DGAT2,CLMN,AURKA,B4GAT1,GDF11,CFAP20,NDE1,DRP2,ARPC2,TRPC3,RPS6KA3,CSRP2,XDH,ADAMTS16,EGLN1,MTM1,PAPSS2,GRHL2,NQO1,LFNG,INPP5D,WDTC1,C5orf30,PKP2,PRKACA,APC2,TNFSF9,RCN1,CCND1,CDH1,DACT1,RTKN2,ACSL4,DLG3,RASGEF1A,MYT1,SNX10,ETV4,SSH3,CAMSAP3,COL6A2,LGALS8,FZD4,SAT1,HTATIP2,SYP,RAB38,TANC1,EBF2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,CORO1C,AXL,WFS1,SIPA1L1,WWTR1,PNPLA6,TRABD2A,RGS14,ARNT,MAPK12,TTC8,CTHRC1,NKX3-1,TNRC6C,FARP1,RBM24,MAN1A2,DCAF7,SDC4,CCM2,BIK,FLOT1,GMCL1,CTSZ,PKN1,PLPPR4,ZNF219,ETS1,GSTP1,HOXB2,SRPX2,ICAM1,SGPL1,NEO1,CTNNBIP1,CAPN2,ZFX,ANK1,PDCD10,IGSF9,IRAK1,ITGB8,CTSC,KNDC1,GPC3,CST3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,RAG1,SGCB,ITM2C,S100A6,POU6F1,ADAMTS2,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,RAB3IP,CRISPLD2,ABLIM2,TXK,CNTNAP1,PITX2,PROM1,ACVRL1,DBI,FAM3C,NR4A3,CENPE,HMGA1,ITGAV,FHL1,OSR1,USF2,SHOX2,FOXA1,PHC1,TLL2,MYL9,TNK1,EPAS1,AGRN,CUL4B,EPHA4,SUDS3,ARFGEF1,PHOSPHO1,NDRG2,F11R,PDGFB,SDC1,SPTB,SLC9A3R2,PLS3,RPS6KA2,PCNA,CTNNB1,NPNT,SHC3,IL6ST,MITF,PAPSS1,PSMC2,ELF5,TMEM143,DUSP10,TNFRSF18,NTN4,NEB,THRB,MARK1,CELSR2,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CLCN2,CDK1,RHEB,PLEKHB1,DZIP1L,DPYSL3,IRX3,HS6ST1,MAP2,HOXA9,POMT1,MAFF,MYL12B,RUNX2,USH1C,LGALS3,RASA2,PSMD7,RACGAP1,CNTNAP2,NCKAP1,FBLN1,DHRS3,PGAP1,IL18R1,ANO1,SSX2IP,BMP2,TNS3,RB1,DAZAP1,VASP,TIMP1,IGF1R,GATA2,FRAS1,KIF13B,PAK2,PIM1,NTN1,WNT3A,ALDH3A2,PSMA5,CYP26B1,DPYSL5,PCDH1,RGMB,STRADB,TCF7,SCRIB,EIF2AK1,UNC45B,G2E3,PRX,SMN1,CDK5R1,FOXD2,MAPKAPK2,MOSPD3,FA2H,COL13A1,PVRL2,MFSD2A,PHLPP2,ITGA7,CSF1,PRPS2,TMEM120A,AKIP1,SEMA3A,CCNB2,CTBP1,NF2,HOXB7,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,STIL,EMP2,SDF4,PER2,TTC21B,PDGFA,TACC2,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,GYS1,CDH3,NOTCH3,SCN2A,MINPP1,DVL2,SULF2,SIRT1,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CDC20,CCSAP,PTGER4,ACO1,MYL12A,DAG1,PTGS2,DUOX1,RTN4RL1,IDE,PTPRJ,PAFAH1B3,PTK7,PSMD3,EFNA5,RPL22,LTA4H,POMGNT2,CTDSP1,BIN1,COL9A3,DYRK3,PACSIN2,CDH22,CD63,ADGRG1,CTSB,MCTP2,GABRG2,PSMD10,GDF15,JAG2,CRABP2,FZD6,PPP2R3A,NRP2,GBX2,ZDHHC21,CD109,FOXP2,CDK16,UBE2J1,TFAP2A,SGK1,HMGCL,SYK,CAMK2G,FAM134C,TLE6,GCNT1,DUSP1,HES1,RHOA,PSMB4,CRIP2,LITAF,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BBS2,PRDX4,BCL10,CNOT2,FAT4,SCG2,TWSG1,FGF18,PGRMC1,E2F1,PKD2,PPP2R3C,CFAP74,GAA,ACVR1,HSPG2,SSH1,LGR4,VANGL1,TMEM41B,CUL1,GATA3,PSME1,CAMK1D,PLXNA1,CCNB1,VASH1,SEPT4,FAM101B,CHST2,PICK1,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,POLL,PIK3CA,TACSTD2,ZBTB18,PACSIN1,SGCE,ACVR1C,CASP9,AURKB,LDB2,CCNF,SAV1,ZFAND5,ULK2,ARHGEF26,SFXN1,HLF,AREG,PLK2,TBX1,PTER,LRIG1,NKD1,BMP1,DHTKD1,SERPINI1,SPRY4,TANC2,UNC5B,F2RL1,LZTS1,FGD1,SEMA6B,KLF2,INPPL1,MRC2,CDKN1C,SLC25A27,NOTCH2,SLC1A3,HERC6,APBA1,TNFRSF19,KIAA1161,MECOM,CALR,DOPEY2,ITGA3,CYR61,BHLHE41,MSH2,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,DLX4,TMED2,GPR161,RIMS2,IGSF3,DNAI1,SPATA20,EPB41L5,MMD,B9D2,CEP89,CALM1,AMER1,DCHS1,ANO6,WHSC1,VEZT,EPHA1,KDM3A,ANTXR1,NFIB,STX3,RASA1,FAS,MMP15,WDR19,MATN2,NAB2,FAM83D,SFMBT1,PCDH19,NR4A2,EFNA1,HOOK1,EHD1,IRF1,ELK4,FOXO6,SPRED1,TCF25,SLC2A4,TCTN2,ST14,THRA,CAST,RPS6KA1,IQGAP1,NDRG1,IRX4,BCL2L1,EGR3,DDR1,FLT3,MNS1,EPM2A,NOV,APLP2,CCNA2,DOK4,CDKN1B,CNNM4,DAB2IP,PDE4D,EPHB4,MED30,SEMA3B,GPX4,FOXJ2,DMTN,UTRN,PRKCQ,SLC11A2,PYGO1,ALCAM,FZD7,CEP162,CMTM7,EPHA10,FYN,JAK1,NGFRAP1,STAT1,RAB29,NRG1,KLF5,PRR15,CBX7,COBL,ATMIN,PRKAR1A,WASF3,PCOLCE,JRKL,HAPLN3,CENPI,PBX3,NES,SEPP1,SPR,FGF19,EFNB1,TEAD3,ADGRB2,SIX4,RND1,E2F7,OXCT1,MGAT1,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,ERCC2,TAGLN2,MAP3K7,CITED2,TTPA,GFI1,SPRY2,OSGIN1,MSH6,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,TCFL5,VAMP3,FURIN,DIAPH2,C1GALT1C1,FBXO9,YES1,FOS,GPLD1,CDK5RAP1,RGS9,TIMP3,CTNS,DGCR2,FGFR2,PRDX3,TBX18,RYK,ERAP1,SERPINB5,GRIN2D,LRRK1,GPER1,FZD5,WDR62,NCAPG2,ARSB,SLC25A38,MELK,RGMA,JARID2,EXPH5,EMX1,CASP3,UGT8,UBE2Q1,MPP5,PLAC1,CACNB4,DNER,TMC1,EPCAM,LRRC6,GRHL1,CDKL5,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,ASH2L,RP2,CTTN,MYH14,ARNT2,BTBD3,SP5,RASGRP1,CYP1B1,ATL1,SOD1,TRIM8,ASXL1,FOPNL,RNF165,ARHGDIB,EDNRA,CXXC4,MDK,GPRC5B,HPSE,TDRD7,TRIM45,NRGN,APBA2,PPP2R5D,PSMC1,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,TEC,DUSP5,SPP1,CA2,LRRN2,FAM20C,OCRL,COL6A1,EBF4,PRKCI,SUCO,FNIP1,NPTN,C10orf54,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,HMG20B,C3orf58,RANBP9,EGFR,FECH,GNAS,BCAR3,ONECUT1,TSC1,INSR,PLPP3,TMEM30A,UTP14C,ALPK3,PITPNA,DONSON,EGFL7,SHROOM2,JAK3,RARG,APOL2,DRD1,KLF7,PAX6,IL15,PSME2,HDAC11,SOD2,COL18A1,TDRKH,MRAS,ZMYND10,OSR2,MICALL2,PHLDA1,EXT2,MXD1,SS18,KCTD15,ARTN,SETDB2,FRYL,KIF14,SMO,RPN2,DIXDC1,TWIST1,ECE1,NFKB2,LOXL1,HSPA2,FRS3,MAP3K3,SOAT1,PTPRU,OSTM1,IGSF8,GLO1,CD40,DUSP4,ARHGAP35,SOCS3,HSF4,ALDH5A1,BFSP1,BHLHB9,STAT6,PEX2,TLE1,PTBP3,OVOL1,SPTBN5,PLXND1,LIFR,ANXA3,SORT1,ARHGEF11,POC1B,FRMD6,ARHGEF7,CIT,LRP4,TGFBR1,COL4A5,AES,ITGA2B,HDAC9,KIF5B,TOP2A,MDM1,ADRBK1,ADORA1,LLGL2,BMP7,MYCL,RRBP1,TOX2,KIAA0319,ACTA2,ARVCF,TRIM3,MTURN,RPGR,MYO5A,ADAM17,WNT10B,CFAP46,NR4A1,ASPM,RC3H2,MBNL3,TTC7A,RUNX3,FAM73B,NDRG3,FOXL1,LEPR,SPAG1,MAP1B,ARHGAP24,LEMD2,CD8A,SWAP70,PRCP,DHRS2,CTSV,SPINT2,RAP2C,CSGALNACT1,ARRB1,HOXB13,CEP41,PLOD3,SOX8,ZMIZ1,L1CAM,AHR,NGEF |
| 1.220e-11 | -25.13 | YANG_BCL3_TARGETS_UP | MSigDB lists | YANG_BCL3_TARGETS_UP | 348 | 99 | 17758 | 2588 |
MYL9,ARHGAP11A,CCNE2,DLGAP5,FOXM1,AASS,TRIM5,PTTG1,TAP1,SOD2,ETNK1,KIF2C,SEPT4,CCNB1,SDC1,TNFSF9,CHST2,ZNF385B,CDKN2C,RAB15,TGFBR3,CCNA2,UBE2T,PLK4,TACSTD2,KIF22,TMEM37,TLN2,MYBL1,RASGRP1,SOAT1,CD55,PFKFB2,USP18,PBK,CDC20,NUSAP1,CDCA2,AURKB,CDK1,ARHGEF26,RBM47,SERPINI1,IRF7,ABCA1,PCSK5,IGFBP6,DEPDC1,SCOC,CKAP2,PARP14,PEX6,DNAJB2,CENPI,CDCA3,RACGAP1,HERC6,MERTK,TOP2A,DTX3L,FAM111A,ANK1,TIMP1,RALGPS2,CTSC,PRC1,SGK3,LIMCH1,BUB1,KNTC1,DGKG,KIF20A,NR4A1,SYBU,SPA17,MBNL3,CALCRL,VWA1,KIF20B,PDK3,IFIT3,TXNDC11,GLT8D2,FAM64A,NMI,SLC25A40,MATN2,DGAT2,NR4A3,E2F1,FAM83D,AURKA,ACADM,CMPK2,SERPINB1,UBE2C,CCNB2,ESPL1,ACOT7 |
| 1.261e-11 | -25.10 | atypical | COSMIC cancer mutations | atypical | 529 | 135 | 17775 | 2585 |
TNK1,ACVR1,VANGL1,CAMKK1,EPHA4,RET,CAMK1D,CDKN2C,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,STK35,PLK1,NEK4,MARK1,ACVR1C,SYNE3,PBK,ROR1,AURKB,IDH1,STK17B,ADRBK2,ULK2,PLK2,LIMK1,MYLK,MAP3K11,HDAC1,MAPK13,RNASEL,PRKAA2,CDK17,PRKAA1,ADCK5,MERTK,BMP2K,RB1,IGF1R,NEK2,DAPK1,ADCK2,MAP3K9,PRKG1,PRKCI,ALPK1,PIM1,MAPK7,PHKG2,TESK1,ADCK3,STRADB,EIF2AK1,PDK3,PDIK1L,EGFR,STK17A,MAPKAPK2,INSR,P4HA3,AURKA,ALPK3,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,NF2,RPS6KA1,TP53,ERBB2,TESK2,GRK6,LPIN3,PRKACA,DDR1,FLT3,CDK14,FAM46A,PLK4,SMO,EPHB4,SCYL3,MAP3K3,ERMP1,AKT1,RIPK2,TEP1,PRKCQ,PKMYT1,MAP3K6,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,PPP2R2D,MAPK12,TAOK2,DYRK3,PINK1,TGFBR1,PKN1,TRIB2,IRAK1,ADRBK1,CDK16,PTEN,SGK3,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,CASK,PGBD1,YES1,TXK,ACVRL1,PRDX3,FGFR2,UACA,HIPK3,MELK |
| 1.386e-11 | -25.00 | endometrium-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-endometrioid_carcinoma | 16526 | 2479 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PAQR7,HPS3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,IFT27,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,AIP,LBR,IL22RA1,VPS26A,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,LMAN2L,DDHD2,DUSP10,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.397e-11 | -24.99 | astrocytoma_Grade_IV | COSMIC cancer mutations | astrocytoma_Grade_IV | 16720 | 2501 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,RNF224,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,PARM1,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,GPR107,CAPN12,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.505e-11 | -24.92 | molecular function regulator | molecular function | GO:0098772 | 1207 | 263 | 16491 | 2452 |
PPP4R4,IBTK,DNAJC3,CACNA2D2,XIAP,PSME1,RIC1,ELMOD2,CALM2,CDKN2C,RGS12,ARHGAP42,PSMD1,STIM1,RGS3,CABP1,PPP1R16A,PIK3CA,KCNS3,RCAN3,TIAM1,CASP9,PRKAR2B,PIF1,PPP1R14C,ARHGEF26,ABR,PIAS3,CAMK2N2,SH2D3C,PPP2R4,AGFG2,SERPINB6,SERPINI1,HSPB1,STARD13,FGD1,CDKN1C,TBC1D1,GPSM2,HPCAL4,BMP2K,SH3RF2,RAC2,RALGPS2,FAM13B,PPP4R1,RANBP1,PRKG1,TBC1D8B,CALM1,RASA1,MMP15,PRKAG2,FNTA,ITPR1,ARAP1,FGD6,CABIN1,SERPINB1,RPS6KA3,DOCK9,DMPK,PLEKHG3,ARHGAP11A,SPRED1,CCDC109B,RPS6KA1,CAST,IQGAP1,RALBP1,PTTG1,RGS20,WDTC1,PKP2,MGST2,GNB2,EPS8L2,CCND1,CD46,APLP2,ST5,ACAP2,SH3BP1,CDKN1B,DAB2IP,RASGEF1A,CDKN2D,TBC1D10B,DOCK4,ATP1B1,PPP2R5A,NGFRAP1,SIPA1L1,PLEKHG1,NRG1,RGS14,DENND5B,PRKAR1A,ARHGEF3,PCOLCE,NKX3-1,FARP1,DEPDC1,ARHGEF40,GSTP1,SNTA1,PPP1R10,CTSC,MCF2L,GPC3,KNDC1,CST3,SGK3,TMBIM6,ERBB3,SPRY2,NCOA2,FARP2,RASGRF1,ARAP2,ARHGEF28,DENND1B,RAPGEF2,PIK3R1,FURIN,RAB3IP,GRTP1,GPLD1,CDK5RAP1,RGS9,TIMP3,PRDX3,RCBTB2,RIN3,SERPINB5,ARFGAP3,CPEB2,CCNC,CASP3,FAF2,AGRN,ARFGEF1,PDGFB,SLC9A3R2,DENND2D,ARHGEF10L,SIPA1L2,PCNA,RABEP2,ARHGEF37,ARL1,DLG1,RGS5,RP2,RASGRP1,KCNIP3,ARHGDIB,PRKRA,VCP,SEC14L2,PLEKHG6,KCNMB4,TBC1D17,ARHGEF19,GPRC5B,MADD,CAB39,RAP1GAP,PPP2R5D,ARAP3,PPP1R2,PPP1R12A,SERPINE2,FXYD3,RASA2,CALM3,RACGAP1,DOCK11,FBLN1,BMP2,TIMP1,NOXA1,RINL,OCRL,TBCD,PAK2,FNIP1,FXYD5,WNT3A,ALS2CL,SPATA13,FBXO8,BCL2L13,CDK5R1,RHPN1,EGFR,RASGRP2,BCAR3,TSC1,SH3BP4,CTSA,ATP1B3,CCNE2,KCNAB3,PSME2,TP53,RASGRP3,CCNL1,ARHGEF16,PPME1,GM2A,CKS2,CHP1,EBAG9,TIMP2,AKT1,DOCK5,SOCS3,ARHGAP35,DNAJC10,MMP17,PSMD3,RCAN2,EFNA5,ARHGAP4,PPP2R2D,ARFGEF3,ANXA3,GCLM,PINK1,ARHGEF11,ARHGEF7,SERPINB9,SBF1,TRIB2,PPP2R3A,SYDE2,CD109,CARD8,LLGL2,CKS1B,H2AFY,SGK1,TSPAN13,HEXIM2,IQGAP3,RPGR,WNT10B,RGCC,COL7A1,MAPK8IP1,BCL10,ARHGAP24,SERPINA1,SPINT2,ARRB1,TBC1D4,ARHGEF9,PKIA,RAB3IL1,ARHGEF4,NGEF |
| 1.508e-11 | -24.92 | Prot_kinase_dom | interpro domains | IPR000719 | 482 | 126 | 18293 | 2672 |
TNK1,ACVR1,CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,MAPK4,CAMK1D,GRK6,FLT3,DDR1,PRKACA,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CDKL5,PASK,PLK4,EPHB4,SCYL3,STK35,MAP3K3,PLK1,NEK4,MARK1,AKT1,RIPK2,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,MAP3K6,STK17B,ADRBK2,CDK1,ULK2,EPHA10,FYN,JAK1,STK26,CDK19,PLK2,PTK7,STK38,LIMK1,AXL,MYLK,KIAA1804,MAP3K11,MAPK13,MLKL,RNASEL,MAPK12,PRKAA2,CDK17,TAOK2,LMTK3,DYRK3,PINK1,NUAK1,CIT,PRKAA1,TGFBR1,TEC,TRIB2,PKN1,MERTK,BMP2K,ADRBK1,IRAK1,IGF1R,CDK16,PAK2,PRKCI,SGK3,DAPK1,PRKG1,NEK2,MAP3K9,SGK1,MAPK11,BUB1,ERBB3,PIM1,MAP3K7,MAPK7,MAST4,PHKG2,SYK,CAMK2G,CASK,MAPKAPK3,TESK1,STRADB,EIF2AK1,YES1,EPHA1,PIM3,ILK,PDIK1L,EGFR,STK17A,TXK,MAPKAPK2,INSR,FGFR2,ACVRL1,CSNK1G1,RYK,AURKA,CDK18,STK39,LRRK1,MAP3K5,JAK3,NRBP1,HIPK3,MELK,RPS6KA3,DMPK |
| 1.512e-11 | -24.91 | skin-malignant_melanoma | COSMIC cancer mutations | skin-malignant_melanoma | 16562 | 2483 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,NAGA,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,PLCG1,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,TMEM200B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,IL22RA1,VPS26A,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,GPR107,CAPN12,REPS2,DLGAP5,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,PAPD5,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.577e-11 | -24.87 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | 7663 | 1270 | 17775 | 2585 |
IBTK,GRIK2,AK7,SLC25A13,PNPLA2,RET,CCNO,TRAPPC8,BAIAP3,SNX9,CARD10,CMTM6,NAPG,MUC4,PAQR5,ATP13A3,DNM2,TMEM37,TIAM1,CPE,MGAT5,NEK4,DSTN,PRKAR2B,PNKD,ABR,ENPP1,PLCG1,ATP7B,CELF5,TRAF3IP1,FAM114A1,NOD2,HDAC1,STARD13,ANXA11,NXT2,RAB23,GPSM2,CCDC64B,MARCH8,TFAP4,RAC2,ZCCHC17,FRY,PAIP2B,MEGF8,RANBP1,MAP3K9,SLAIN2,CADPS2,USP38,ALPK1,CNGA1,ZMYM1,MOXD1,MYLIP,DGKG,KANK3,NUP85,PPP6R1,TTLL1,MCCC2,HPS3,PQLC3,SHARPIN,KIF20B,NPHP3,GOLT1A,PCTP,SFXN5,GNA11,CACHD1,ETS2,CLMN,OSCP1,TMEM173,DOCK9,NQO1,RHBDL3,APOO,MGST2,FAM91A1,MOCS1,KIAA1147,APPBP2,RCN1,RBM23,MUC16,ST5,CDH1,SH3BP1,LRP11,TMCC2,MX1,COL6A2,RIPK2,PFKFB2,AGPS,PTPN9,SEPT6,SAT1,TANC1,ZNF618,GIGYF1,GABARAPL1,SPIN3,PDLIM3,CCNB3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,FAM149A,DMWD,PRIMA1,ISOC1,MZT1,MPZL1,FAM189A2,CKAP2,TRAF2,HABP4,CCM2,SDC4,BTN3A1,SLC25A43,NFAT5,BEX2,CTNNBIP1,ITGB8,KNDC1,MGAT4A,TUBGCP6,FAM20B,FAM102A,IGFBP2,ADAMTS2,PLSCR1,PIK3R1,CXorf57,AK4,RAB3IP,C4orf27,PROM1,PLOD2,RAB11FIP2,SYT7,SLC35B3,FAM3C,PPM1H,ITGAV,CMPK2,TLL2,KIAA1462,EPAS1,ARFGEF1,LMCD1,TEX2,NENF,GALM,ITPR2,SPTB,PLS3,INPP5E,NUP210,TM9SF2,RABEP2,NPNT,IL6ST,PAPSS1,SLC44A1,TMEM143,NTN4,THRB,PTPN18,MARK1,KCNIP3,CELSR2,CKAP2L,EAF2,SESN1,TRUB1,DZIP1L,TRIM9,PI4K2B,HS6ST1,TRAM2,KCNMB4,KLF12,ZNF367,TC2N,HS6ST3,RRAGD,USH1C,SORBS3,ADCK5,RAB6A,NCKAP1,FBLN1,MYO5C,TNS3,UBE2Q2,FRAS1,AHCY,PIM1,FAR2,WNT3A,NTN1,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,ZNF320,BCL2L13,NMT2,C18orf8,FA2H,KBTBD2,PHLPP2,P4HA3,ZDBF2,PLD1,SEMA3A,CDAN1,USP43,CTDSPL,TMX4,TP53,RHPN2,PCBP1,STIL,PDGFA,TTC21B,WDR44,TACC2,LMO4,PPME1,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,LMAN1,SULF2,CLCN3,ERLEC1,AKT1,DAG1,PTGS2,IDE,PTPRJ,RBL1,ABHD12,STK38,MAOA,EFNA5,SYT13,ST3GAL1,FAM134B,BIN1,PINK1,CDH22,CPEB4,TAB3,KLHL13,CTSB,SCD5,GNAL,MCTP2,ERCC6L,HMGN3,IL22RA1,VPS26A,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,C16orf74,LYPD6,UBE2J1,GTF2F2,IL17RA,SGK1,CPLX1,ALDH7A1,ATP2B1,LRRC24,NFE2L3,P2RX4,FBLN5,RHOA,MOSPD2,PLAUR,PRICKLE1,DPP9,MAML2,GGH,RNPEP,TXNDC11,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,HIPK3,ARHGEF4,GOLGB1,FAM171B,SLC35D2,TXN,LGR4,HSPG2,SSH1,VANGL1,C1orf198,CUL1,PDGFRL,SEPT4,VASH1,OAT,SLC9A7,PAK6,ANKS6,STIM1,OSBPL3,SERINC2,PIK3CA,KCNS3,SNX16,IRF2,HYLS1,METAP2,SPATA18,ACVR1C,CDYL,BNIP3L,KIF13A,LDB2,POR,RAB2B,PRIM1,GDE1,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,SPRY4,SLC31A2,FGD1,RECQL,MRC2,SCOC,TBC1D1,PRKAA1,TXNDC9,APBA1,TNFRSF19,TSPAN7,SH3RF2,DOPEY2,RALGPS2,ZNRF2,AIM1,MSH2,DAPK1,PRKG1,ADCK2,TPST1,OSTF1,CACNA1D,KCTD3,GCC2,CEP89,LPGAT1,PYGL,WHSC1,ANTXR1,NFIB,PDE11A,NT5C2,SLCO4A1,PLEKHH2,TJP3,PELI2,C1orf21,PIAS2,MPP2,FAM83D,APPL2,CABIN1,CDK18,PER3,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,GPR107,NDRG1,ATP2C2,FAM78A,TMEM19,FLT3,CYP39A1,ZFYVE9,EPM2A,CD46,ACAP2,RALB,FLOT2,MED30,ATG4D,COG2,PANK1,CLSTN1,UTRN,TMEM144,PYGO1,ATP1B1,B3GALNT2,CBL,ITPR3,ASB13,ALCAM,ATP10D,ZNF704,COBL,MAMDC2,PLSCR4,CENPI,EPS8,CBLL1,HERC5,PBX3,DNAH3,FGF19,CKAP5,SLC25A36,WWP2,RASSF8,RNF128,FUT8,CCDC82,MSH6,FARP2,PDGFC,ARHGEF28,PAPD7,DIAPH2,C2orf69,UBAC1,YES1,GRTP1,KIF11,DCTN6,ACADSB,DGCR2,SEC14L4,RIN3,ABCB1,ERAP1,WDR91,WDR62,MELK,DEF6,RGMA,FAF2,UGT8,CRYM,MPP5,ERP29,ECI1,ADPRHL1,EPCAM,SIPA1L2,CDKL5,CASC4,ANKFN1,TRPC1,MYRIP,LAMP3,ASXL1,LAP3,ACBD3,ITCH,HPSE,KCNK1,MADD,TDRD7,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R2,PPP1R12A,PYROXD2,ETV5,ABCG2,CALM3,FAM81A,ADAMTSL4,QSOX2,DUSP5,SPP1,TYW3,FAM20C,OCRL,COL6A1,PRKCI,SRP54,LIMCH1,BRAT1,C10orf54,NPTN,ZRANB1,ETV7,SLC12A2,SNED1,ELK3,PODXL2,SPA17,VWA1,PDE5A,KIAA1109,HEATR5A,STEAP1,RANBP9,RHPN1,SOX13,INSR,UAP1,TMEM30A,SPAG7,DCUN1D1,SH3BP4,RAB31,NXPH4,SHROOM2,COL16A1,SNX30,DRD1,LMO7,DYNLRB1,NCKAP5,PAX6,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,ZNF687,CYP4F11,KIF14,REEP1,DIXDC1,ZBTB49,EPB41L4B,ECE1,UPF3A,SEPHS1,SOAT1,RFK,PTPRU,MRPS35,CD40,TMTC2,CDC25C,PDHX,CASP4,ALDH5A1,STAT6,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,GLIS3,ARHGEF11,TSPAN15,SHPRH,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,RBP7,XPR1,HMGXB4,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,H2AFY,KANK2,CLIP2,SLC35A1,MYO5A,RBMS2,SYBU,TTC7A,NDRG3,LEMD2,SWAP70,CASP7,RND3,SPINT2,CSGALNACT1,ARRB1,GRAMD1C,ZMIZ1,AHR,ABCG1,NGEF,ACACB,TRIM24,ADD1,IL15RA,AASS,DNAJC3,MMADHC,CACNA2D2,SMARCAL1,DHX8,NRG2,LYNX1,LGI3,SYTL4,CA8,KIF26A,BARD1,EPDR1,CALM2,DAPK2,TP73,WEE1,PSMD1,TGFBR3,RGS12,AP1M2,ARHGAP42,KIAA1107,DNAH6,CABP1,ALDH1A3,SEMA3G,PIK3CD,APOBEC3G,ODF2L,ERAP2,SH3BGRL,RNF11,LOXL2,F12,PPP1R14C,MYOM1,COL12A1,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,AGFG2,SERPINB6,MRPS28,RELL1,GAB1,FAM169A,NFKBIE,TMTC3,CYP2J2,SLC36A4,MERTK,LMNA,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,SLC37A1,SALL4,STAT4,MYBL2,CALCRL,PLS1,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,SCARB2,MTFMT,SEMA4D,HTT,SETD3,ITPR1,DYSF,OSMR,DRP2,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,RGS20,ETNK1,WDTC1,PKP2,TESK2,IL13RA1,PRKACA,APC2,ZNF385B,UHRF1BP1L,CDS1,SCNN1A,RNF220,RTKN2,TMEM9,SCN3A,RNF169,ENPP4,LGALS8,PLEKHO1,SYNE2,CDCA2,RAB38,IRS2,WWTR1,SIPA1L1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,TNRC6C,MAN1A2,RASSF7,PDIA3,ANO9,NUCB2,ETS1,TSPAN17,SRPX2,ICAM1,PDIA4,NEO1,CAPN2,ADD3,SLC27A6,ARSG,CTSC,ANKS1B,KCNK5,CALD1,WWP1,NPTXR,TMX1,AMOTL2,LCA5,FMN1,FAM160A1,CTNNAL1,RAPGEF2,GRIN1,PLEKHA7,BLVRA,NEURL1B,SNTB1,CRISPLD2,ABLIM2,TXK,PITX2,DCAF10,BTG1,NR1D2,CCDC6,ZFP30,ARFGAP3,SHOX2,USF2,CYBRD1,DCBLD1,AGRN,GNPDA1,CUL4B,EPHA4,MCCC1,SDC1,SHC3,ELF5,DUSP10,RGS5,TLN2,ANO4,TRAM1,MYBL1,DDX59,CCDC38,ZNF462,MCTP1,EZR,ERP44,ANLN,FAM212B,IDH1,LHFPL2,VCP,RHEB,DPYSL3,PLCH1,WIPI1,MAP2,P4HA2,PIK3C2B,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,ZCCHC24,UBASH3B,CNTNAP2,DOCK11,DHRS3,C3orf18,IL18R1,PGAP1,SSX2IP,CORO1B,DAZAP1,KIAA0895,IGF1R,MDFIC,ALDH3A2,PSMA5,C9orf9,CHSY3,CYP26B1,MRPS33,WDR72,CORO2A,TCF7,PRPS2,LTBP2,ATP1B3,CTBP1,NF2,UGP2,XYLT1,ERBB2,CCDC68,LPIN3,KBTBD11,SDF4,C1orf116,PER2,CDK14,SRPX,EFR3A,PLCG2,MINPP1,EGLN3,SIRT1,TMTC1,MBP,COQ10B,MYPOP,DNAJC10,RTN4RL1,ATP1A1,PTK7,ADAMTS14,ANXA9,LTA4H,AIFM3,NDST3,CMTM4,MAN2B2,COL9A3,GOLIM4,PACSIN2,TRAPPC10,MACC1,RUSC2,DAP,GNE,BLVRB,GABRG2,JAG2,CHAC2,DSE,SLC9A2,PPP2R3A,CCDC92,MAGEE1,SLC35B4,ABCD1,IGDCC4,DLGAP1,MLEC,IFITM3,NR3C1,LITAF,PPARA,CAPNS1,FNDC3A,MAPK8IP1,PRDX4,CD83,TMEM50B,BANK1,FAT4,CDCA7L,NETO2,FAM117A,CLIP4,PKD2,TBC1D4,NDFIP1,GAA,ACVR1,PPP4R4,TMEM41B,FAM129B,ATP8A1,KLC2,PPFIBP2,TAP1,GATA3,PLXNA1,PLA2G16,ELMOD2,NCS1,SESN3,IQCE,PRICKLE3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,RCAN3,PACSIN1,ORAI2,LOC81691,SNTB2,HSPA12A,CASP9,TNS1,GALNT7,MCFD2,CCNF,TP53I3,SPNS3,ULK2,ARHGEF26,SGPP1,AHRR,SFXN1,GNPTAB,NKD1,DHTKD1,UNC5B,TANC2,TRAF5,RTN3,LZTS1,DDX58,KLF2,CDK17,MRPL44,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,NOTCH2,SLC1A3,PRRG4,ITGA3,PIK3AP1,BDH1,RUNDC3B,OPN3,SORL1,CD70,PIKFYVE,TSPAN33,EEF1D,FAM69A,DNAI1,EPB41L5,QSOX1,FADS2,PMPCB,DDB2,KIAA1841,TBC1D8B,MICB,PTPRH,KDM3A,FBXO10,GLT8D2,STX3,RASA1,FAS,DGKH,PRKAG2,ISM1,DCK,SLC4A3,FGD6,PCDH19,MAP3K5,PKD1L2,PLA2G4A,FRMPD3,CEP70,RPS6KA1,SUZ12,IQGAP1,IRX4,NUDT12,MNS1,TMPRSS4,SLC25A35,APLP2,FAM46A,FICD,CDKN1B,CNNM4,PHKA2,NR2C1,MYO5B,SLC5A11,CDKN2AIP,TEP1,COX11,PRKCQ,BCL7B,C15orf39,AKR1E2,SP4,ZNF469,NIN,PRDM11,CMTM7,EPHA10,FYN,JAK1,PPP2R5A,KIAA1804,STAT1,PPP1CB,KLF5,NRG1,ZC3H12B,HS3ST3B1,NR3C2,ATMIN,DENND5B,MRPS9,OTUD5,WASF3,SLC16A14,ATP9A,CCNJL,SPR,TMCC3,OXCT1,PTEN,ATP8B1,OSGIN1,RASGRF1,ARAP2,CASK,TEF,FURIN,PARP4,LRRC1,RGS9,PRDX3,SLC25A40,AMMECR1,CCDC69,SERPINB5,PGM2L1,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,OCLN,JARID2,ESYT2,EXPH5,LTBP1,ST13,TMEM184B,EPHX4,DNER,KREMEN1,DENND2D,TMC1,SH3KBP1,ABCD4,NKAIN3,ARHGEF10L,LRRC6,TSPAN6,IMPAD1,DPYSL2,PHTF1,DLG1,ANKRD12,AKR1B1,POF1B,SUN3,RP2,NFU1,MYH14,ARNT2,SLC39A10,TECR,PTPRE,RASGRP1,OLFML2A,TDP1,ATL1,TRIM8,SYNE3,RNF165,MRPS18A,ROR1,MRPS36,PTGFRN,ADRBK2,STK17B,TCN2,EDNRA,SEC14L2,CXXC4,ARHGEF19,FASTKD1,IARS2,APBA2,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,ELOVL7,ASL,PHLPP1,AIM1L,CA2,EBF4,FNIP1,KNTC1,ALS2CL,HP1BP3,PARD3B,OXR1,FBXO8,EGFR,MUM1L1,GLCE,GNAS,XKRX,BCAR3,ONECUT1,TSC1,ALPK3,PITPNA,KIF12,KLF7,PROM2,GAS2L1,ZSWIM5,SPC25,FAM92A1,IL15,MORC4,GMPR,MICALL2,LRRC45,SLC25A48,SS18,SETDB2,KHNYN,FRYL,SMO,RPN2,F2R,LOXL1,SUSD3,GCA,ZNF525,TAF5,BAG4,SLC39A8,OSTM1,DUSP4,DOCK5,BFSP1,OVOL1,PLXND1,CYP2U1,AKNA,LIFR,ANXA3,CDS2,SORT1,JKAMP,POC1B,ARMC7,LRP4,MIER3,TRMT2B,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,TRIM3,FAM219A,SYPL1,ADAM17,RAB3B,ASPM,GCLC,DEPDC4,MBNL3,LRRC66,OGDHL,MPV17L2,SPAG1,MAP1B,KLHL2,UBE2D2,OTUB2,SOX8,ATP6V1C1,GEM |
| 1.612e-11 | -24.85 | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN | MSigDB lists | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN | 197 | 66 | 17758 | 2588 |
CASP3,MTM1,TXN,DLGAP5,GNPDA1,KIF2C,CDKN2C,PCNA,CCNA2,UBE2T,CAPG,PLK4,KIF22,TMEM37,SNX10,CKS2,CENPA,S100A4,DSTN,SH3BGRL,NUSAP1,AURKB,CCNF,ANLN,DOCK5,CDC25C,CDK1,PRIM1,CARHSP1,SERPINB6,E2F8,CD99,LGALS3,GCAT,SERPINB9,CDCA8,CDCA3,EFHD2,BMP2K,TOP2A,CAPN2,CA2,NEK2,PRC1,CKS1B,MDFIC,BUB1,S100A6,SYPL1,KIF20A,PLSCR1,IFITM3,ASPM,FHL2,LITAF,EMP3,KIF11,C4orf27,PRDX4,GALNT3,H1F0,CDCA5,AURKA,GEM,CCNB2,ACOT7 |
| 1.859e-11 | -24.71 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | 279 | 84 | 17758 | 2588 |
TCF25,KIAA1462,AGRN,THRA,ERBB2,NUP210,METTL7A,DPYSL2,PLCG2,ABCA2,GYS1,GLB1L2,EPHB4,MARCH2,NOTCH3,LOXL1,MGAT5,CTDSP2,NAGA,GM2A,CELSR2,HSPA12A,CLSTN1,CBX6,ESYT1,ITPR3,IDH1,H2AFV,POR,DAG1,ABR,ARHGAP35,LRRC42,ALDH5A1,PTK7,STAT6,ATP7B,WFS1,FAM114A1,PNPLA6,ST3GAL1,CAPN1,LASP1,GALK1,SERPINE2,ENO2,ITGA6,ZCCHC24,LRP4,SBF1,IFT27,PDIA4,TMEM63A,GNS,DOPEY2,RIMS3,BDH1,FDXR,TBCD,RRBP1,CD9,SORL1,NPTXR,MSH6,IGSF3,FADS2,DDB2,UFD1L,ADAM17,MLEC,SHMT1,MAPKAPK3,PARP4,FBXO9,TCF7,STEAP1,FUCA1,PTPRF,CTNS,ITGA7,ITPR1,PITPNA,CTSA,GLB1 |
| 2.172e-11 | -24.55 | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP | 168 | 59 | 17758 | 2588 |
CCDC109B,DEPDC1,DLGAP5,HJURP,FOXM1,ELOVL7,SOX9,PTTG1,NDC80,KIF23,RACGAP1,NUF2,KIF2C,PM20D2,CCNB1,BARD1,DDR1,FANCI,MECOM,TOP2A,CCNA2,KIF14,PRC1,NEK2,TMEM51,NCEH1,SLC39A10,ETV4,CKAP4,SMC4,ABCC1,TUBA4A,ZWINT,MMD,KIF20A,SALL4,ASPM,PBK,CDC20,CKAP2L,NUSAP1,LRRC1,GALNT7,AURKB,ANLN,LHFPL2,KIF11,SKA1,CDK1,ATP1A1,PAFAH1B3,CDCA5,CDCA7L,AURKA,MAPK13,CENPE,UBE2C,CCNB2,E2F8 |
| 2.258e-11 | -24.51 | phosphorus metabolic process | biological process | GO:0006793 | 2000 | 401 | 16441 | 2455 |
ACACB,ACVR1,TRIM24,SSH1,AASS,AK7,SLC25A13,PNPLA2,HEXB,RET,CUL1,NRG2,PSME1,IL18,CAMK1D,CCNB1,PLA2G16,SLC20A1,PICK1,GRM5,CALM2,DAPK2,PAK6,WEE1,TYMP,PSMD1,TGFBR3,IL31RA,PALD1,SERINC2,PIK3CA,PPP1CA,PIK3CD,NEK4,ACVR1C,PBK,AURKB,TP53I3,ULK2,SLC44A3,SGPP1,ENPP1,PLCG1,PLK2,SH2D3C,LIMK1,GNPTAB,MYLK,NOD2,MAP3K11,DHTKD1,MAPK13,RNASEL,ITPKA,GAB1,DLAT,CDK17,INPPL1,NUAK1,TMEM55B,DGKQ,SOX9,PRKAA1,NDUFA4,ISYNA1,MERTK,TNFRSF19,BMP2K,ATP5H,PPP4R1,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,NCAM1,MAPK7,MAST4,DGKG,PHKG2,MCCC2,PIGC,GFPT1,PMPCB,MMD,ADCK3,MAPKAPK3,STAT4,LPGAT1,CALM1,PTPRH,PIP4K2C,PYGL,CALCRL,EPHA1,PKM,ELK1,ILK,SPTLC2,PSMA4,RASA1,PDE11A,STK17A,DGKH,PTPRF,NT5C2,PRKAG2,CSNK1G1,DCK,MPP2,DGAT2,AURKA,MDH1,STK39,CDK18,SAMD8,MAP3K5,NRBP1,RPS6KA3,XDH,DMPK,PLA2G4A,SPRED1,MTM1,DLGAP5,PAPSS2,INPP5D,RPS6KA1,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,NUDT12,MOCS1,EPM2A,CDS1,CCND1,DOK4,DAB2IP,PDE4D,EPHB4,ACSL4,DLG3,PHKA2,RASGEF1A,SULT2B1,GPX4,SSH3,RIPK2,PFKFB2,PTPN9,PANK1,PRKCQ,PXYLP1,ATP1B1,PKMYT1,XRCC6BP1,EPHA10,IRS2,FYN,JAK1,ACYP1,CDK19,STK26,AXL,INPP4B,KIAA1804,PNPLA6,PPP1CB,SLC27A1,NRG1,PDXK,MLKL,MAPK12,GALK1,TAOK2,CCM2,PLD2,PKN1,PLPPR4,FGF19,IRAK1,PTEN,FAM20B,SGK3,SLC44A2,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,RASGRF1,CASK,SHMT1,PLSCR1,MPP1,RAPGEF2,PIK3R1,DUSP23,ELOVL3,GRIN1,AK4,PIM3,YES1,FOS,TXK,GPLD1,CTNS,FGFR2,ACVRL1,SLC35B3,DBI,PLA2G15,PPM1H,RYK,PGM2L1,GRIN2D,ITGAV,LRRK1,CMPK2,ACOT7,MELK,TNK1,NMRK1,PPM1J,CAMKK1,EPHA4,PHOSPHO1,CDIPT,CACNB4,PDGFB,PIGL,SPTB,INPP5E,RPS6KA2,ENTPD4,SHC3,CDKL5,IMPAD1,PSMC2,PAPSS1,PASK,SLC44A1,PAPL,DLG1,DUSP10,TECR,PTPRE,RASGRP1,STK35,PLK1,MARK1,PTPN18,ROR1,PRKRA,IDH1,CDK1,ADRBK2,STK17B,VCP,PLCH1,PI4K2B,NEIL1,FASTKD1,AGPAT2,DOLPP1,CAB39,PIK3C2B,CHPT1,PSMC1,PPP2R5D,CPPED1,PRKAA2,LMTK3,PPP1R12A,RASA2,UBASH3B,ELOVL7,PSMD7,CALM3,ADCK5,TEC,PHLPP1,DUSP5,PGAP1,BMP2,IGF1R,PFKL,FAM20C,OCRL,PAK2,PRKCI,MDFIC,NPTN,PIM1,FAR2,PLCB2,PSMA5,MDFI,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,EGFR,CDK5R1,GNAS,MAPKAPK2,NUDT16,INSR,PLPP3,PHLPP2,PRPS2,ALPK3,PLD1,JAK3,CTBP1,UGP2,IL15,PSME2,CTDSPL,DGKA,ERBB2,P2RX7,GMPR,RASGRP3,LPIN3,CDK14,PDGFA,PLCG2,PLK4,MINPP1,FAR1,F2R,CTDSP2,SCYL3,FRS3,SEPHS1,MAP3K3,AKT1,RFK,FIGNL1,PTPRU,PTGER4,DUSP4,CDC25C,PDHX,MAP3K6,PTGS2,ALDH5A1,ATP1A1,PTPRJ,ABHD12,STK38,PTK7,PSMD3,SPTBN5,ST3GAL1,CTDSP1,CDS2,PINK1,DYRK3,ENO2,TAB3,CIT,GNE,PSMD10,TGFBR1,TRIB2,SBF1,PPP2R3A,ADRBK1,ALPP,CDK16,SGK1,BUB1,HMGCL,IQGAP3,SYK,CAMK2G,DUSP1,PGM1,PSMB4,PLAUR,OGDHL,NADK2,RUNX3,MAPK8IP1,DGKE,PRDX4,SCG2,FGF18,HIPK3 |
| 2.277e-11 | -24.51 | PLASARI_TGFB1_TARGETS_10HR_DN | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_DN | 234 | 74 | 17758 | 2588 |
LMO7,TRIM2,REPS2,NQO1,LGR4,DDIT4L,IL18,RASGRP3,NUF2,CCNB1,SESN3,TGFBR3,METTL7A,IL6ST,DIXDC1,ARNT2,IFIT1,SCARA3,CYP1B1,SMARCA2,FIGNL1,SH3BGRL,USP18,CBX6,BNIP3L,NUSAP1,PRKAR2B,LDB2,IDH1,SESN1,PRIM1,NFIX,MAP2,STAT1,PLEKHG1,RNASEL,LIFR,SERPINB9,HERC6,DHRS3,FOXP2,PTEN,CENPJ,TRIM21,BUB1,SLC12A2,MSH6,TLE6,PARP9,EPHX1,HMMR,CTNNAL1,PIK3R1,MBNL3,PDE5A,MEST,IFIT3,NFIB,MUM1L1,PLEKHH2,FAT4,RCBTB2,NR1D2,FGFR2,RND3,NMI,WDR19,CLIP4,ACADM,OSR1,PER3,SHOX2,SEMA3A,SERPINB1 |
| 2.282e-11 | -24.50 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | 722 | 171 | 17758 | 2588 |
ACACB,BCAM,PNISR,ADD1,FAM199X,HEBP1,ATP8A1,EPHA4,SUDS3,FHDC1,TEX2,F11R,LTBP3,EPCAM,TGFBR3,CTGF,STIM1,METTL7A,TSPAN6,RGS5,RCAN3,CPE,TNS1,SESN1,POR,DPYSL3,PGF,ANKRD10,TMEM164,WDR11,MYLK,LRIG1,CTNND1,MAPK13,RELL1,GLCCI1,CHPT1,RAP1GAP,CAPN1,TBC1D1,DNAJB2,DHRS3,FBLN1,B3GALNT1,SPP1,TNS3,CES2,BHLHE41,FBXO7,MTMR10,PCYOX1,OPN3,SORL1,SLAIN2,LIMCH1,STT3B,ACAD8,MYLIP,ALDH3A2,MCCC2,SNED1,EPB41L5,WDR72,PQLC3,SPATA13,GNAS,NUDT16,SCARB2,CACHD1,PRKAG2,SLC4A4,MATN2,NFKBIA,ITPR1,CLMN,PITPNA,EFNA1,LTBP2,MAP3K5,PLIN3,PER3,TOB1,RNF146,PROM2,SPRED1,GRHL2,HDAC11,ERBB2,KCTD12,DDR1,EPM2A,CDS1,APLP2,ST5,ENPP5,EPB41L4B,LGMN,ARL4D,TMBIM1,TMTC1,MBP,ERMP1,TMEM43,PFKFB2,SYNE2,C3orf52,PTGER4,HTATIP2,ERBB2IP,DOCK5,ALDH5A1,ATP1A1,PPP1CB,ST3GAL1,LIFR,CBX7,MAN2B2,WASF3,PINK1,ARHGEF3,TRAPPC10,MPZL1,CPEB4,ARHGEF7,SCD5,CTSB,SLC41A1,GNAL,CYB561,SEPP1,H1FX,NEO1,TMCC3,CCDC92,ADD3,ITGB8,PTEN,LLGL2,RRBP1,CST3,FAM63A,ACTA2,SGK1,ERBB3,CITED2,TPCN1,FAM134C,GCNT1,HES1,ARAP2,ALDH2,TEF,TCFL5,TTC7A,STMN3,FBXO9,SNTB1,LEPR,BSDC1,PROM1,SERPINA1,NR1D2,FAM3C,ERAP1,FAM117A,FZD5,TBC1D4,HIPK3,CYBRD1,ABCG1,GOLGB1 |
| 2.469e-11 | -24.42 | regulation of transferase activity | biological process | GO:0051338 | 986 | 223 | 16441 | 2455 |
CCNC,CASP3,TXN,IBTK,DNAJC3,CAMKK1,EPHA4,CUL1,NRG2,PSME1,CCNB1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,CTNNB1,SHC3,RGS3,PSMC2,SERINC2,PIK3CA,DLG1,DUSP10,RASGRP1,PLK1,NEK4,SOD1,PRKAR2B,PIF1,AURKB,CDK1,PLCG1,CAMK2N2,GPRC5B,LIMK1,MADD,NOD2,MAP3K11,CAB39,HSPB1,PSMC1,GAB1,PIFO,CDKN1C,UBASH3B,RASA2,PRKAA1,PSMD7,CALM3,DUSP5,BMP2,TFAP4,RAC2,RB1,IGF1R,CYR61,FBXO7,PAK2,NEK2,MAP3K9,SORL1,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,SOCS5,MMD,MAPKAPK3,CALM1,STRADB,PDE5A,EPHA1,ILK,PSMA4,EGFR,RASA1,CDK5R1,MAPKAPK2,TSC1,PRKAG2,INSR,CSF1,NLRC5,DCUN1D1,STK39,EFNA1,MAP3K5,JAK3,DRD1,CCNE2,SPRED1,AVPI1,NF2,GRHL2,IQGAP1,PSME2,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,FLT3,EMP2,STIL,CCND1,PDGFA,APLP2,CCNA2,RALB,KIF14,CDKN1B,DAB2IP,RASGEF1A,CDKN2D,F2R,HSPA2,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,PSRC1,RIPK2,AKT1,NRBF2,FZD4,PFKFB2,CDC20,COX11,PRKCQ,PKMYT1,DUSP4,CD40,CDC25C,MAP3K6,SOCS3,IRS2,FYN,PTPRJ,JAK1,PPP2R5A,CCNB3,STK26,RBL1,PSMD3,STK38,CORO1C,WWTR1,KIAA1804,SLC27A1,EFNA5,SPTBN5,NRG1,RGS14,PRKAR1A,PINK1,TAOK2,NKX3-1,TAB3,TRAF2,SDC4,PSMD10,HERC5,TGFBR1,PKN1,TRIB2,GSTP1,FGF19,PARM1,DIRAS3,PDCD10,ADORA1,IRAK1,PTEN,BMP7,BAX,CKS1B,H2AFY,BUB1,MAPK11,HEXIM2,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,DUSP1,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,PIK3R1,GRIN1,RGCC,MAPK8IP1,CDK5RAP1,FGFR2,PRDX3,FGF18,RAP2C,ARRB1,PPP2R3C,GRIN2D,PKD2,CENPE,FZD5,CD81,UBE2C,HIPK3,PKIA |
| 2.542e-11 | -24.40 | regulation of phosphate metabolic process | biological process | GO:0019220 | 1669 | 344 | 16441 | 2455 |
TXN,PPP4R4,ACVR1,IBTK,GRIK2,TRIM5,DNAJC3,NRG2,PSME1,IL18,CCNB1,SNX9,BARD1,CARD10,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,CTGF,RGS3,IL31RA,PIK3CA,CRY2,NEK4,TNIP1,PBK,CDA,PRKAR2B,PPP1R14C,ENPP1,PLCG1,CAMK2N2,DNM1L,AREG,ANKRD6,TBX1,TRAF3IP1,PPP2R4,NOD2,MAP3K11,SPRY4,HSPB1,F2RL1,GAB1,CDKN1C,NUAK1,ITGA6,SOX9,PRKAA1,SH3RF2,MECOM,TFAP4,RAC2,CYR61,FBXO7,MAP3K9,SORL1,MYDGF,NCAM1,MAPK7,PPP6R1,GPR161,SOCS5,MMD,MAPKAPK3,CALM1,KCTD20,CALCRL,EPHA1,NPHP3,ILK,PSMA4,RASA1,FAS,PRKAG2,HTT,SEMA4D,PELI2,FAM83D,STK39,EFNA1,GDF11,MAP3K5,XDH,EGLN1,SPRED1,IQGAP1,PRKACA,FLT3,CCND1,APLP2,ST5,CCNA2,RALB,DACT1,CDKN1B,DAB2IP,PDE4D,DLG3,RASGEF1A,CDKN2D,CAMSAP3,PSRC1,RIPK2,NRBF2,FZD4,PFKFB2,DMTN,COX11,CDCA2,RAD17,PKMYT1,FZD7,IRS2,FYN,JAK1,CCNB3,PPP2R5A,STK26,WFS1,CORO1C,WWTR1,KIAA1804,SLC27A1,NRG1,RGS14,ARNT,PRKAR1A,FARP1,HSP90B1,NKX3-1,TAOK2,TRAF2,SDC4,FLOT1,HERC5,PKN1,GSTP1,SRPX2,TIPRL,FGF19,ICAM1,DIRAS3,PDCD10,IRAK1,PTEN,KNDC1,BAX,MAPK11,ERBB3,MAP3K7,SPRY2,RASGRF1,PDGFC,RAPGEF2,PIK3R1,GRIN1,YES1,GPLD1,CDK5RAP1,FGFR2,PRDX3,ACVRL1,RYK,GRIN2D,GPER1,CENPE,LRRK1,FZD5,CD81,CCNC,CASP3,CAMKK1,EPHA4,NDRG2,NENF,PDGFB,ERP29,SPTB,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,DLG1,DUSP10,TNFRSF18,SLC39A10,RASGRP1,PLK1,SOD1,ITCH,EZR,IDH1,CDK1,VCP,EDNRA,KDM4D,GPRC5B,MADD,PRKCDBP,CAB39,PPP2R5D,PSMC1,PRKAA2,PIFO,LMTK3,PPP1R2,PPP1R12A,RASA2,UBASH3B,PSMD7,CALM3,SORBS3,TEC,PHLPP1,FBLN1,DUSP5,BMP2,RB1,IGF1R,PAK2,FNIP1,BRAT1,MDFIC,NPTN,PIM1,WNT3A,PSMA5,CCDC88A,MDFI,STRADB,PDE5A,EIF2AK1,RANBP9,EGFR,CDK5R1,GNAS,FECH,BCAR3,MAPKAPK2,TSC1,INSR,PLPP3,CSF1,NLRC5,JAK3,PROM2,DRD1,CCNE2,AVPI1,NF2,IL15,FOXM1,PSME2,CTDSPL,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,EMP2,STIL,SYTL2,IER3,PDGFA,PPME1,KIF14,TWIST1,APIP,F2R,CTDSP2,HSPA2,DVL2,FRS3,CKS2,CHP1,MAP3K3,PPIF,SIRT1,TIMP2,BAG4,AKT1,DUSP4,CD40,CDC25C,MAP3K6,DAG1,C3orf33,SOCS3,DNAJC10,PTPRJ,RBL1,STK38,PSMD3,SPTBN5,EFNA5,PPP2R2D,ABCA1,CNEP1R1,CTDSP1,ARFGEF3,PINK1,TAB3,LRP4,GNAL,PSMD10,TGFBR1,GDF15,TRIB2,PPP2R3A,SH2D4A,CD109,ADORA1,BMP7,CKS1B,H2AFY,HEXIM2,IQGAP3,SYK,CAMK2G,DUSP1,HES1,ADAM17,RHOA,PSMB4,PLAUR,RGCC,PPARA,MAPK8IP1,BCL10,LEMD2,BANK1,SWAP70,RAP2C,FGF18,ARRB1,PPP2R3C,PKD2,UBE2C,HIPK3,PKIA |
| 2.558e-11 | -24.39 | nervous system development | biological process | GO:0007399 | 2292 | 450 | 16441 | 2455 |
DOC2A,HSPG2,SSH1,AK7,TMEM41B,RET,MCOLN3,HEXB,GATA3,NRG2,PSME1,PLXNA1,CAMK1D,SEPT4,KIF26A,NCS1,PICK1,GRM5,CALM2,TP73,CDKN2C,WEE1,PSMD1,ALDH1A3,DNM2,SEMA3G,PACSIN1,ZBTB18,TIAM1,SMARCA2,SPEF2,TFAP2C,ULK2,ARF4,ABR,PLCG1,AREG,LIMK1,TBX1,PLK2,TRAF3IP1,NKD1,LRIG1,SERPINI1,TMOD2,UNC5B,ITPKA,ARF6,LZTS1,SEMA6B,SCN5A,CDKN1C,SOX9,RAB23,SLC1A3,NOTCH2,APBA1,HPCAL4,MECOM,CALR,RAC2,ITGA3,FRY,FLRT3,MEGF8,ZIC5,PRKG1,SORL1,TNFRSF12A,CACNA1D,NCAM1,PIKFYVE,MYLIP,DGKG,RIMS2,MMD,SALL4,CALM1,SHARPIN,DCHS1,KIF20B,EPHA1,ILK,DPYSL4,NFIB,PSMA4,STX3,RHOB,RASA1,FAS,PTPRF,TIMM8A,SEMA4D,HTT,MATN2,NAB2,CLMN,PCDH19,AURKA,NR4A2,EFNA1,B4GAT1,GDF11,ARPC2,NDE1,DRP2,TRPC3,RPS6KA3,EHD1,SPRED1,FOXO6,GRHL2,ST14,NDRG1,THRA,IQGAP1,CAST,RPS6KA1,EGR3,PRKACA,EPM2A,APLP2,CDH1,DACT1,DOK4,DAB2IP,EPHB4,ACSL4,RASGEF1A,DLG3,ETV4,MYT1,SEMA3B,SSH3,CAMSAP3,COL6A2,FZD4,SLC11A2,PRKCQ,ALCAM,FZD7,NFIX,EPHA10,IRS2,FYN,JAK1,SHROOM3,AXL,SLC9A6,SIPA1L1,RAB29,NRG1,RGS14,COBL,WASF3,CTHRC1,FARP1,JRKL,HAPLN3,SDC4,FLOT1,PBX3,NES,PLPPR4,SPR,SEPP1,GSTP1,ETS1,HOXB2,EFNB1,FGF19,SIX4,ADGRB2,TEAD3,RND1,NEO1,ANK1,OXCT1,IGSF9,PTEN,KNDC1,CST3,BAX,CD9,ATP8B1,WWP1,ERBB3,ERCC2,MAP3K7,GFI1,ITM2C,S100A6,FARP2,POU6F1,RASGRF1,TGIF1,PDGFC,B3GNT2,ARHGEF28,FMN1,TACC1,RAPGEF2,GRIN1,AK4,YES1,FOS,ABLIM2,CDK5RAP1,PITX2,CNTNAP1,RGS9,TIMP3,PROM1,CTNS,FGFR2,DBI,NR4A3,RYK,GRIN2D,GPER1,ITGAV,FZD5,WDR62,ARSB,SHOX2,FOXA1,JARID2,RGMA,MYL9,CASP3,EMX1,UGT8,AGRN,CUL4B,EPHA4,SUDS3,ARFGEF1,NDRG2,MPP5,DNER,PDGFB,CACNB4,TMC1,SPTB,PLS3,RPS6KA2,CTNNB1,CDKL5,SHC3,DPYSL2,IL6ST,PSMC2,DLG1,DUSP10,TRPC1,NTN4,ARNT2,CTTN,MYH14,BTBD3,RASGRP1,ATL1,SOD1,MARK1,CELSR2,RNF165,EZR,KLK6,CDK1,RHEB,IRX3,DPYSL3,EDNRA,MDK,HS6ST1,GPRC5B,MAP2,APBA2,NRGN,PSMC1,PPP2R5D,MYL12B,NR2C2,GRN,USH1C,RUNX2,SERPINE2,RASA2,ETV5,PSMD7,CALM3,RACGAP1,CNTNAP2,NCKAP1,DUSP5,PGAP1,BMP2,RB1,SPP1,VASP,IGF1R,LRRN2,GATA2,KIF13B,PAK2,COL6A1,PRKCI,NPTN,NTN1,WNT3A,ALDH3A2,PSMA5,CCDC88A,DPYSL5,PCDH1,RGMB,HMG20B,TCF7,SCRIB,RANBP9,SMN1,CDK5R1,PRX,EGFR,TSC1,FA2H,TMEM30A,PHLPP2,CSF1,PLPP3,PITPNA,JAK3,SHROOM2,SEMA3A,RARG,KLF7,DRD1,PAX6,NF2,PSME2,HDAC11,TP53,ERBB2,RASGRP3,MICALL2,PHLDA1,STIL,SDF4,PER2,TTC21B,PDGFA,ARTN,TACC2,KIF14,LMO4,FRYL,LHX6,SRR,BCL6,SMO,TWIST1,DIXDC1,NOTCH3,SCN2A,DVL2,SULF2,FRS3,MBP,TIMP2,AKT1,CDC20,IGSF8,MYL12A,DAG1,ARHGAP35,ALDH5A1,PTPRJ,RTN4RL1,PAFAH1B3,BHLHB9,PTK7,PSMD3,PEX2,EFNA5,SPTBN5,PLXND1,LIFR,POMGNT2,CTDSP1,BIN1,ANXA3,COL9A3,CDH22,ARHGEF11,ADGRG1,CIT,ARHGEF7,LRP4,PSMD10,COL4A5,TGFBR1,JAG2,CRABP2,ITGA2B,NRP2,FZD6,PPP2R3A,GBX2,HDAC9,KIF5B,FOXP2,ADORA1,LLGL2,CDK16,MYCL,BMP7,KIAA0319,TFAP2A,TRIM3,SGK1,RPGR,TLE6,MYO5A,FAM134C,CAMK2G,HES1,RHOA,PSMB4,WNT10B,ASPM,STMN3,PRICKLE1,RUNX3,BBS2,MAP1B,BCL10,LEMD2,FAT4,TWSG1,CTSV,FGF18,SPINT2,CSGALNACT1,E2F1,PGRMC1,PKD2,PLOD3,SOX8,L1CAM,NGEF |
| 2.686e-11 | -24.34 | upper_aerodigestive_tract | COSMIC cancer mutations | upper_aerodigestive_tract | 13823 | 2136 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,FRY,FBXL14,MAP3K9,USP1,PANX2,MAPK7,NUP85,PPP6R1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,RBM23,MUC16,ENPP5,ZNF365,MYT1,SNX8,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,HSP90B1,CKAP2,ESRP1,BIK,HABP4,CCM2,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,TUBGCP6,BAX,KLC3,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,PGBD1,RAB3IP,CNTNAP1,SYT7,FAM3C,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,TRIM9,PI4K2B,TMEM164,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,RHPN2,PCBP1,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,IRF7,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,DNAJB9,ZDHHC21,FOXP2,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PNISR,LGR4,SSH1,HSPG2,TMEM86B,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,FGD1,RECQL,CDKN1C,TBC1D1,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GCC2,PRODH,KLK5,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,NAGA,ATG4D,DOCK4,CYB5R2,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,ACAD10,NGFRAP1,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,EPS8,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,ACADSB,DGCR2,FGFR2,RIN3,TBX18,WDR62,ESPL1,CXorf56,DEF6,RGMA,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,IL1RAP,CXXC5,CENPA,ASXL1,ITCH,RGAG1,MAN2A2,HPSE,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,ETV5,ABCG2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,ETV7,GAD1,SNED1,SNX7,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,RAB31,NXPH4,CTSA,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,TLE1,SPTBN5,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,ARRB1,UACA,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,PLEKHO1,CYS1,RAB38,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,AK3,TPCN1,HCN3,NUDT8,RAPGEF2,EIF5A2,PLEKHA7,EMP3,SNTB1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,ASAH1,DOCK11,PGAP1,KIAA0895,GATA2,SPIN4,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,AVPI1,NF2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,GYS1,EGLN3,SIRT1,TMTC1,CDC20,DUOX1,ATP1A1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,RUSC2,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,BUB1,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,NR3C1,AMFR,LITAF,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,BANK1,TWSG1,ZNF214,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,IQCD,TFG,SMYD5,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,NKD1,DHTKD1,EIF4EBP2,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,B4GALT3,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,ARL4C,GPR180,APOBEC3H,PNPLA5,TMCC3,SNTA1,OXCT1,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,OSGIN1,PCCB,CASK,SHMT1,MPP1,DENND1B,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,RCBTB2,PGM2L1,CSTF2,ETAA1,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,NKAIN3,C7orf49,LRRC6,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,MDK,CXXC4,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,KIF12,PROM2,SPC25,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,ZDHHC12,FRYL,SMO,RPN2,STEAP3,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,FRMD6,FAM134A,TRMT2B,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,AK7,GRIK2,RET,TRAPPC8,LACTB2,BAIAP3,SNX9,LTBP3,CARD10,ZNF275,NPM2,CDKN2C,NAPG,MUC4,TMEM37,WBP4,RNF26,TIPARP,TIAM1,MGAT5,CDA,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,MEGF8,RIMS3,RANBP1,FBXO7,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,KIF20B,PSMA4,GNA11,SFXN5,IL1R1,S100A5,CLMN,CBX5,DOCK9,ADAMTS16,TPRN,LFNG,CD82,APOO,RHBDL3,PTTG1,FAM91A1,GRK6,REPS1,MOCS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,MX1,TMCC2,COL6A2,SEC61B,PFKFB2,SAT1,GIGYF1,EBF2,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,IFT27,SGPL1,CTNNBIP1,SLC25A45,ZFX,PDCD10,ITGB8,TMEM62,KNDC1,CST3,RAG1,PARP9,ADAMTS2,UBE2A,CXorf57,AK4,C4orf27,LDLRAP1,PROM1,PLOD2,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,CD81,PHC1,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,CTNNB1,TM9SF2,IL6ST,ARL1,MITF,SLC44A1,PSMC2,PAPSS1,SCARA3,THRB,KRT80,PLK1,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,ZNF367,KPNA2,TC2N,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,VAT1,NOTCH3,LMAN1,KIAA0040,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PPP2R4,PRDM5,MAPK13,SEMA6B,MRC2,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,RPL39,VASN,TPST1,DAPK1,DLX4,SOCS5,SPATA20,KCNJ12,LPGAT1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,FAM64A,FAAH,MATN2,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,CAPN12,GPR107,REPS2,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,FTH1,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ZMPSTE24,AMZ2,DDOST,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,CAB39,GLA,RBM43,CHPT1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,KANK2,CLIP2,RPGR,SLC35A1,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,WEE1,ARHGAP42,PQLC2,RGS12,PSMD1,DNAH6,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,E2F8,GAB1,HOXC13,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,OSMR,DYSF,MDH1,SERPINB1,RPS6KA3,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,WWP1,MAPK11,NKAPP1,NPTXR,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,FOXA1,DCBLD1,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,HN1L,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,MYL12A,DNAJC10,C19orf66,PTK7,ADAMTS14,ZBTB6,NDST3,CMTM4,GSDMD,MACC1,GABRG2,JAG2,DSE,CRABP2,MAGEE1,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PPARA,CCDC34,CAPNS1,TRIM35,BSDC1,MAPK8IP1,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,PKD2,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,ISM1,DCK,FGD6,NR4A2,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CAPN6,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,JRKL,ATP9A,CCNJL,CYB561,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,CASP3,LTBP1,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,ZCCHC12,CAPG,DLG1,ANKRD12,POF1B,RP2,ARNT2,SLC39A10,TECR,RASGRP1,OLFML2A,ATL1,TDP1,FOPNL,RNF165,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,MIIP,PSMC1,GRN,FAM213B,ATP6V1E2,SAMD9,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,RFX5,KNTC1,LRIF1,ALS2CL,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,PSME2,SLC2A8,MORC4,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,OVOL1,CYP2U1,PLXND1,AKNA,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,POMGNT1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,ADAM17,ASPM,GCLC,NR4A1,POLD3,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,UBE2D2,HOXB13,GEM |
| 2.881e-11 | -24.27 | BILD_E2F3_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_E2F3_ONCOGENIC_SIGNATURE | 226 | 72 | 17758 | 2588 |
CCNE2,HECA,UGT8,FAM92A1,EPHX4,C5orf30,CCNO,MRAS,CHST2,ZNF275,CDKN2C,RAB15,PCNA,KCTD15,SCNN1A,FAM46A,REEP1,CEP78,ZDHHC23,AKR1B1,ATRNL1,EPB41L4B,TIAM1,TMEM200B,CXXC5,AKT1,TMEM43,TRIM7,NIN,ALDH5A1,CDK19,ZNF367,LRIG1,KIAA1804,TMOD2,PLXND1,EPB41L4A,SLC27A3,FAM134B,RRAGD,CDKN1C,ENO2,LRP4,GNAL,DGKQ,ABCG2,PSIP1,SSX2IP,PRRG4,SAC3D1,RAVER2,IL17RB,E2F7,LYPD6,SLC16A6,TRIM3,KANK2,ZWINT,AK4,RUNX3,CD83,GNAS,MMP15,DDAH1,INSR,DCK,NETO2,SFMBT1,DONSON,CMPK2,NIPA1,DIS3L |
| 3.476e-11 | -24.08 | ductal_carcinoma | COSMIC cancer mutations | ductal_carcinoma | 16643 | 2491 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,TAF6L,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,IL22RA1,VPS26A,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,CERCAM,NDRG1,RALBP1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,ZIC5,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 3.721e-11 | -24.01 | negative regulation of signal transduction | biological process | GO:0009968 | 1023 | 229 | 16441 | 2455 |
SIGIRR,LTBP1,TNK1,ACVR1,LGR4,GATA3,NDRG2,PSME1,KIF26A,GRM5,SH3KBP1,TP73,PSMD1,RGS12,TGFBR3,CTNNB1,IL6ST,RGS3,TSPAN6,PSMC2,DLG1,DNM2,DUSP10,RGS5,CRY2,PPP1CA,CTTN,PTPRE,TNIP1,ASXL1,ITCH,PBK,SLC35C1,EZR,TNFAIP8L1,SLC25A5,OPTN,CXXC4,ENPP1,ANKRD6,TRAF3IP1,MADD,NKD1,NOD2,PRKCDBP,HDAC1,CTNND1,SPRY4,UNC5B,HSPB1,F2RL1,PSMC1,PRKAA2,RUNX2,ARAP3,BMF,SERPINE2,LGALS3,NUAK1,ITGA6,UBASH3B,RASA2,SOX9,PRKAA1,PSMD7,ZNRF3,PHLPP1,FBLN1,DHRS3,DUSP5,LMNA,MECOM,BMP2,CALR,RB1,ITGA3,IGF1R,PIK3AP1,GATA2,VASN,DAPK1,FNIP1,SORL1,MAPK7,WNT3A,PSMA5,GPR161,MDFI,SOCS5,CYP26B1,AMER1,STRADB,NPHP3,PSMA4,RANBP9,EGFR,G2E3,PLIN5,RASA1,TSC1,ONECUT1,HTT,NFKBIA,ITPR1,SH3BP4,PIAS2,NLRC5,EGFL7,NR4A2,TOB1,IFI6,XDH,SPRED1,NF2,NLRX1,FOXM1,LFNG,INPP5D,DDIT4L,PSME2,RGS20,TP53,SOD2,P2RX7,BCL2L1,PRKACA,APC2,CYP26A1,ZFYVE9,EPM2A,IER3,CCND1,CD46,NOV,DACT1,BCL6,TAX1BP3,DAB2IP,TWIST1,LGMN,CDKN2D,TMBIM1,DVL2,CHP1,SULF2,CTH,SIRT1,PPIF,TIMP2,AKT1,KREMEN2,FIGNL1,PRKCQ,ERBB2IP,CBL,DUSP4,DAG1,C3orf33,ARHGAP35,SOCS3,FYN,PTPRJ,PSMD3,STK38,WFS1,WWTR1,STAT1,TLE1,TRABD2A,PPP1CB,NRG1,RGS14,ZC3HC1,GCLM,CTHRC1,PINK1,NKX3-1,ARHGEF7,LRP4,PSMD10,TGFBR1,AES,PLD2,NOTUM,GSTP1,ICAM1,HMGXB4,PPP2R3A,FZD6,CD109,CTNNBIP1,SNX13,CARD8,ADRBK1,PTEN,BMP7,GPC3,BAX,TMBIM6,KANK2,ERBB3,FAIM,MAP3K7,SPRY2,DUSP1,TGIF1,ADAM17,RHOA,PSMB4,PLAUR,GCLC,LITAF,PRICKLE1,STMN3,CARD19,PELI3,MAPK8IP1,LEMD2,CNOT2,ARHGAP24,RGS9,BANK1,TWSG1,SCG2,TBX18,ARRB1,ITGAV,GPER1,HIPK3 |
| 3.787e-11 | -24.00 | GSE7460_TCONV_VS_TREG_LN_DN | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_DN | 196 | 65 | 17758 | 2588 |
CCNE2,KIAA1462,NDRG1,BLCAP,CD274,BCL2L1,HDAC6,OSBPL3,ZDHHC23,TNFRSF18,TMEM64,LMAN1,F2R,MGAT5,SOAT1,SH3BGRL,PTGER4,KIF13A,DUSP4,PRKRA,SESN1,CASP4,GABARAPL1,PIAS3,AXL,LRIG1,TDRD7,NFKBIZ,TANC2,RRAGD,TTC8,NFKBIE,UBASH3B,FRMD6,ATP9A,TGFBR1,NCKAP1,PHLPP1,BMP2K,HDAC9,SNX13,IGF1R,SNX18,MDFIC,ITM2C,SLC12A2,SOCS5,ELK3,MAPKAPK3,CORO2A,PRICKLE1,CD83,BANK1,CASP7,FNTA,ACADSB,TWSG1,MATN2,DGAT2,ABCB1,SH3BGRL2,GEM,TBC1D4,CD81,AHR |
| 3.832e-11 | -23.98 | Protein_kinase_ATP_BS | interpro domains | IPR017441 | 378 | 104 | 18293 | 2672 |
TNK1,ACVR1,CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,MAPK4,CAMK1D,GRK6,FLT3,PRKACA,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CDKL5,PASK,PLK4,EPHB4,STK35,PLK1,NEK4,MARK1,AKT1,ACVR1C,PRKCQ,PKMYT1,AURKB,MAP3K6,ADRBK2,STK17B,CDK1,ULK2,FYN,JAK1,STK26,CDK19,PLK2,STK38,LIMK1,AXL,MYLK,KIAA1804,MAP3K11,MAPK13,MAPK12,PRKAA2,CDK17,TAOK2,LMTK3,DYRK3,NUAK1,CIT,PRKAA1,TGFBR1,TEC,PKN1,MERTK,ADRBK1,IRAK1,IGF1R,CDK16,PAK2,PRKCI,SGK3,DAPK1,PRKG1,MAP3K9,SGK1,MAPK11,BUB1,PIM1,MAP3K7,MAPK7,PHKG2,SYK,CAMK2G,MAPKAPK3,TESK1,EIF2AK1,YES1,EPHA1,PIM3,PDIK1L,EGFR,TXK,STK17A,MAPKAPK2,INSR,FGFR2,ACVRL1,CSNK1G1,AURKA,CDK18,STK39,MAP3K5,JAK3,HIPK3,MELK,RPS6KA3,DMPK |
| 3.935e-11 | -23.96 | cytoskeleton organization | biological process | GO:0007010 | 860 | 199 | 16441 | 2455 |
SUN1,CFAP74,UGT8,SSH1,ADD1,AK7,NDC80,XIAP,F11R,CNTROB,KIF2C,FAM101B,SH3KBP1,PAK6,WEE1,ZYX,LRRC6,CTNNB1,ELMO2,DPYSL2,DLG1,TUBG1,SUN3,RP2,MYH14,CTTN,TLN2,PACSIN1,DNAAF3,PLK1,SPEF2,SOD1,MARK1,CENPA,SYNE3,STRIP2,FOPNL,UXT,DSTN,EZR,ARHGDIB,AURKB,ANLN,CDK1,LCP1,ABR,DPYSL3,MAP2,PLK2,LIMK1,PPP2R4,PRKCDBP,TMOD2,ITPKA,ARF6,FGD1,ARAP3,INPPL1,USH1C,PPP1R12A,SOX9,KIF23,SORBS3,RACGAP1,GPSM2,NCKAP1,LMNA,SSX2IP,CORO1B,CALR,FLII,RB1,RAC2,VASP,FRY,PAK2,TBCD,NEK2,PRKG1,PRKCI,SLAIN2,LIMCH1,ZRANB1,MAST4,TTLL1,DNAI1,EPB41L5,GCC2,KIF20A,CORO2A,MYBL2,FBXO8,STRADB,PLS1,ANTXR1,RANBP9,PVRL2,HTT,ARAP1,FGD6,AURKA,NDE1,ARPC2,SHROOM2,FBXW5,GAS2L1,MTM1,SORBS1,SPC25,NF2,TMSB15A,TRIP10,TESK2,PKP2,MRAS,ZMYND10,MICALL2,EMP2,STIL,TMSB15B,PDGFA,SS18,TACC2,FRYL,KIF14,BCL6,PLK4,ESPN,EPB41L4B,CHP1,CAMSAP3,PSRC1,FIGNL1,CAPN6,DMTN,SYNE2,VPS4B,NUSAP1,ERBB2IP,DAG1,NIN,PDLIM3,SHROOM3,PTK7,CORO1C,SIPA1L1,TRIOBP,SPTBN5,RGS14,ARHGAP4,SGOL1,COBL,PRKAR1A,WASF3,TAOK2,HSP90B1,PACSIN2,ARHGEF11,SH3D19,EPS8,PLD2,SPDL1,SIX4,RND1,CKAP5,ANK1,PDCD10,LLGL2,PTEN,CENPJ,TUBGCP6,PRC1,SPRY2,FARP2,SUN2,RHOA,ARHGEF28,CFAP46,TACC1,FMN1,ASPM,DIAPH2,STMN3,KIF11,BBS2,BCAR1,ABLIM2,SPAG1,MAP1B,CNTNAP1,DCTN6,SWAP70,RND3,ARRB1,PPP2R3C,PKD2,CENPE,WDR62,ESPL1 |
| 4.203e-11 | -23.89 | lung-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour-atypical | 522 | 132 | 17775 | 2585 |
TNK1,ACVR1,VANGL1,CAMKK1,EPHA4,RET,CAMK1D,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,STK35,PLK1,NEK4,MARK1,ACVR1C,SYNE3,PBK,ROR1,AURKB,ADRBK2,STK17B,ULK2,PLK2,LIMK1,MYLK,MAP3K11,HDAC1,MAPK13,RNASEL,PRKAA2,CDK17,PRKAA1,ADCK5,MERTK,BMP2K,RB1,IGF1R,NEK2,DAPK1,PRKCI,MAP3K9,ADCK2,PRKG1,ALPK1,PIM1,MAPK7,PHKG2,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,EGFR,STK17A,MAPKAPK2,INSR,P4HA3,ALPK3,AURKA,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,NF2,RPS6KA1,TP53,TESK2,ERBB2,GRK6,LPIN3,PRKACA,DDR1,FLT3,CDK14,FAM46A,PLK4,EPHB4,SCYL3,MAP3K3,ERMP1,AKT1,RIPK2,TEP1,PRKCQ,PKMYT1,MAP3K6,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,PPP2R2D,MAPK12,TAOK2,DYRK3,PINK1,TGFBR1,PKN1,TRIB2,ADRBK1,IRAK1,PTEN,CDK16,SGK3,SGK1,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,CASK,PGBD1,YES1,TXK,FGFR2,ACVRL1,PRDX3,UACA,HIPK3,MELK |
| 4.222e-11 | -23.89 | endometrium | COSMIC cancer mutations | endometrium | 16541 | 2479 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PAQR7,HPS3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,IFT27,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,AIP,LBR,IL22RA1,VPS26A,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,LMAN2L,DDHD2,DUSP10,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 4.362e-11 | -23.86 | protein kinase activity | molecular function | GO:0004672 | 599 | 149 | 16491 | 2452 |
LTBP1,TNK1,ACVR1,TRIM24,CAMKK1,RET,EPHA4,PDGFRL,CAMK1D,CCNB1,DAPK2,PAK6,WEE1,TGFBR3,RPS6KA2,CDKL5,PASK,PIK3CA,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,AURKB,ROR1,STK17B,CDK1,ADRBK2,ULK2,FASTKD1,LIMK1,PLK2,MYLK,MAP3K11,MAPK13,RNASEL,ITPKA,PRKAA2,LMTK3,CDK17,NUAK1,PRKAA1,SOX9,ADCK5,TEC,MERTK,BMP2K,IGF1R,FAM20C,PAK2,DAPK1,MAP3K9,ADCK2,PRKG1,PRKCI,NEK2,NPTN,ALPK1,PIM1,MAPK7,MAST4,PHKG2,MMD,MAPKAPK3,TESK1,STRADB,EIF2AK1,EPHA1,PDK3,ILK,PDIK1L,EGFR,CDK5R1,STK17A,MAPKAPK2,INSR,PRKAG2,CSNK1G1,ALPK3,AURKA,STK39,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,RPS6KA1,ERBB2,TESK2,MAPK4,GRK6,PRKACA,DDR1,FLT3,CDK14,CCND1,PLK4,EPHB4,PHKA2,MAP3K3,AKT1,RIPK2,PRKCQ,PKMYT1,XRCC6BP1,MAP3K6,EPHA10,FYN,JAK1,CDK19,STK26,PTK7,AXL,STK38,KIAA1804,MLKL,MAPK12,TAOK2,PINK1,DYRK3,CIT,TGFBR1,PKN1,TRIB2,NRP2,IRAK1,ADRBK1,CDK16,SGK3,SGK1,MAPK11,BUB1,ERCC2,ERBB3,MAP3K7,SYK,CAMK2G,CASK,PIM3,YES1,TXK,ACVRL1,FGFR2,RYK,LRRK1,HIPK3,MELK |
| 4.931e-11 | -23.73 | CROONQUIST_IL6_DEPRIVATION_DN | MSigDB lists | CROONQUIST_IL6_DEPRIVATION_DN | 98 | 41 | 17758 | 2588 |
CCNE2,GALK1,SPC25,FOXM1,AASS,PTTG1,KIF2C,CCNB1,STIL,FANCI,TOP2A,WEE1,SPP1,PCNA,CCNA2,KIF14,PLK4,CKS1B,BUB1,KIF22,KNTC1,SMC4,SEPHS1,CKS2,HMMR,PLK1,CENPA,ZWINT,CDC20,MYBL2,GGH,AURKB,CCNF,KIF11,CDK1,AURKA,KPNA2,HMGA1,CENPE,UBE2C,CCNB2 |
| 4.962e-11 | -23.73 | Golgi membrane | cellular component | GO:0000139 | 665 | 160 | 17570 | 2579 |
SLC35D2,UNC93B1,IL15RA,ARFGEF1,MGAT5B,PJA2,CDIPT,PDGFB,SLC9A7,CHST2,NCS1,CHPF,INPP5E,ENTPD4,AP1M2,ARL1,LMAN2L,CABP1,STEAP2,FUT1,DNM2,TFG,SCARA3,MGAT5,RASGRP1,ATL1,ACBD3,SLC35C1,KIF13A,GALNT7,MCFD2,RAB2B,RHEB,OPTN,MAN2A2,HS6ST1,AREG,WIPI1,GNPTAB,ATP7B,NRGN,RAP1GAP,CHPT1,RTN3,LMTK3,SCOC,HLA-E,HLA-F,NOTCH2,RAB6A,B4GALT4,QSOX2,B4GALNT1,B3GALNT1,DOPEY2,SLC30A6,PRKCI,TPST1,HLA-C,PIKFYVE,NCAM1,PPP6R1,MPHOSPH9,TMED2,KDELR1,NAGPA,CHSY3,B3GNT7,QSOX1,MGAT4B,GYLTL1B,GOLT1A,C3orf58,ZDHHC3,EGFR,GLCE,GNAS,RAB31,ARAP1,ZDHHC7,B4GAT1,PLD1,LFNG,GALNT12,APOO,XYLT1,ATP2C2,FAM198B,APC2,EMP2,EXT2,BCAP31,PDGFA,XYLT2,NOTCH3,LMAN1,CHP1,EBAG9,CLCN3,SEC23A,COG2,CLSTN1,PXYLP1,PKMYT1,B3GALNT2,TAPBP,STX10,STK26,CANT1,HS3ST3B1,B4GALT3,ST3GAL1,NDST3,COPG1,SORT1,GOLIM4,TRAPPC10,MAN1A2,CTSZ,POMGNT1,DSE,PARM1,HLA-A,ZDHHC21,PDCD10,FUT2,CTSC,MGAT1,A4GALT,MGAT4A,FAM20B,FUT8,ZDHHC13,SLC35B4,SLC35A1,GCNT1,B3GALT6,MOB4,PDGFC,B3GNT2,SYBU,FURIN,C1GALT1C1,COL7A1,FNDC3A,GALNT3,HLA-B,NUCB1,LDLRAP1,SERPINA1,RND3,SLC35B3,CSGALNACT1,ARRB1,ARFGAP3,GPER1,FZD5,NDFIP1,ABCG1,GOLGB1 |
| 5.487e-11 | -23.63 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | 180 | 61 | 17758 | 2588 |
ANXA3,TRIM2,AGRN,ALDH6A1,CDKN1C,CAST,IQGAP1,BLVRB,CTDSPL,ASAH1,KCTD12,COL4A5,IL27RA,TGOLN2,SEPP1,MERTK,CARD10,MECOM,CDS1,PLS3,SPP1,SP100,CDH1,OXCT1,FRY,EFR3A,LLGL2,KIF13B,PLCG2,MITF,TPST1,TACSTD2,IFIT1,IL10RB,OLFML2A,AMOTL2,LAMP2,NR3C1,DSTN,PLS1,ATP1B1,LDB2,ALCAM,ATP10D,CYB5A,IL1R1,FUCA1,TRAM2,NCOA3,ATP1A1,PPP2R5A,GPRC5B,ETS2,PRCP,AXL,PRPS2,MATN2,MYLK,FAM3C,PDXK,TOB1 |
| 5.555e-11 | -23.61 | central_nervous_system | COSMIC cancer mutations | central_nervous_system | 17176 | 2548 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,RNF224,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,GPR107,CAPN12,REPS2,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,C17orf75,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 5.865e-11 | -23.56 | regulation of Ras protein signal transduction | biological process | GO:0046578 | 185 | 63 | 16441 | 2455 |
PLEKHG3,TNK1,ARHGEF3,FARP1,ARAP3,ADGRG1,FOXM1,ARHGEF11,ARHGEF7,RASA2,ARFGEF1,FLOT1,ERBB2,NOTCH2,ARHGEF40,ARHGEF16,SSX2IP,EPS8L2,ARHGEF10L,PDCD10,ITGA3,RALGPS2,ARHGEF37,KIF14,MCF2L,BCL6,DNM2,DAB2IP,RASGEF1A,TIAM1,F2R,ALS2CL,SPRY2,RASGRP1,FARP2,RASGRF1,TIMP2,ARHGEF28,SPATA13,FBXO8,STMN3,ICMT,ABR,ARHGEF26,RASA1,ARHGAP35,ARHGAP24,PLEKHG6,ARHGEF19,CSF1,MADD,PLEKHG1,FGD6,ARRB1,NRG1,ARF6,F2RL1,ABCA1,ARHGEF9,ARHGEF4,FGD1,NGEF,ARFGEF3 |
| 6.109e-11 | -23.52 | cellular component organization or biogenesis | biological process | GO:0071840 | 5468 | 957 | 16441 | 2455 |
DOC2A,ACACB,ADD1,GRIK2,MRPS15,AASS,TRIM5,AK7,PNPLA2,HEXB,RET,CACNA2D2,XIAP,CCNO,NRG2,TRAPPC8,CNTROB,MORF4L2,SYTL4,SNX9,CARD10,LTBP3,PHF1,TP73,NPM2,CALM2,WEE1,NAPG,ZYX,PHYHIP,PSMD1,AP1M2,TGFBR3,DNM2,TUBG1,SEMA3G,TIAM1,CPE,TUBA4A,DNAAF3,NEK4,SPEF2,SMARCA2,VPS11,DSTN,UXT,CDA,MTRF1L,PRKAR2B,LOXL2,ICMT,MYOM1,ARF4,GINS4,LCP1,COL12A1,ABR,PLCG1,MID1IP1,DNM1L,LIMK1,TRAF3IP1,MYLK,NOD2,HDAC1,MRPS28,TMOD2,RNASEL,ITPKA,ARF6,SCN5A,SEC61G,ITGA6,SOX9,RAB23,GPSM2,MERTK,LMNA,ATG4A,ELF3,TFAP4,FLII,RAC2,ZCCHC17,FRY,MEGF8,RIMS3,FLRT3,FBXO7,FAM13B,NEK2,SLAIN2,ALPK1,PANX2,NCAM1,NUP85,TTLL1,PPP6R1,NAGPA,REC8,HPS3,KIF20A,PYM1,ERO1A,SHARPIN,MYBL2,PLS1,KIF20B,SRSF5,NPHP3,ILK,TP53INP2,DPYSL4,PSMA4,RHOB,PLIN5,PTPRF,NCOA3,FNTA,MTFMT,TIMM8A,HTT,SEMA4D,SETD3,TEX30,AURKA,DYSF,CLMN,MDH1,B4GAT1,NDE1,ARPC2,CFAP20,TRPC3,NUP58,RPS6KA3,DMPK,MTM1,GRHL2,TMSB15A,TUBB4B,LFNG,ACTR8,APOO,PTTG1,C5orf30,WDTC1,PKP2,TESK2,NUF2,PRKACA,CCND1,CDH1,SP100,DACT1,ACSL4,DLG3,RASGEF1A,ETV4,SNX10,SNX8,CAMSAP3,SSH3,SEC61B,PSRC1,COL6A2,FZD4,SYNE2,CYS1,VPS4B,SYP,CDCA2,NUSAP1,RAB38,GTF2A2,TANC1,SNX12,COX20,GABARAPL1,IRS2,PEX5,PDLIM3,SHROOM3,CORO1C,SLC9A6,AXL,SIPA1L1,WWTR1,RGS14,MAPK12,TTC8,CTHRC1,FARP1,TAOK2,HSP90B1,TRAF2,CCM2,BIK,SDC4,FLOT1,CTSZ,ANO9,PKN1,PLPPR4,KCNC4,ETS1,IFT27,TSPAN17,ICAM1,NEO1,DTX3L,ANK1,PDCD10,ITGB8,IGSF9,IRAK1,CTSC,FAM160A2,CST3,TUBGCP6,BAX,PLEKHF1,ADAM15,MAPK11,RAG1,S100A6,CRTAP,ACBD5,PVRL4,ADAMTS2,LCA5,PLSCR1,TACC1,FMN1,RAPGEF2,GRIN1,UBE2A,PLEKHA7,EMP3,RAB3IP,FAM109A,SKA1,CRISPLD2,ABLIM2,CNTNAP1,RPL12,PLOD2,ATXN7L3,SYT7,SLC35B3,NR4A3,SSNA1,ITGAV,CENPE,HMGA1,NUP37,WDR45B,SRSF9,FOXA1,PHC1,TLL2,MYL9,AGRN,EPAS1,CUL4B,EPHA4,SUDS3,ARFGEF1,NDC80,LMCD1,F11R,HDAC6,PDGFB,SDC1,SPTB,SLC9A3R2,INPP5E,PCNA,RPS6KA2,NUP210,CTNNB1,NPNT,SHC3,P4HB,CNTRL,ARL1,PSMC2,MITF,NTN4,TLN2,ANO4,TRAM1,NEB,ZNF462,PLK1,KCNIP3,MARK1,ING1,CELSR2,CBX6,C12orf65,EZR,ARFRP1,ANLN,CDK1,VCP,OPTN,DZIP1L,DPYSL3,KDM4D,MSL1,MAP2,WIPI1,PRKCDBP,CTNND1,POMT1,TC2N,MYL12B,PRKAA2,USH1C,HJURP,LGALS3,RASA2,PDCL,PSMD7,SORBS3,RACGAP1,NCKAP1,CNTNAP2,FBLN1,SSX2IP,CORO1B,BMP2,RB1,VASP,TIMP1,IGF1R,PAK2,TBCD,FCHO1,EXOC8,NTN1,WNT3A,PSMA5,CYP26B1,DPYSL5,MRPS33,TESK1,RGMB,CORO2A,SPATA13,STRADB,SCRIB,ZDHHC3,SMN1,NMT2,CDK5R1,FA2H,H1F0,COL13A1,PVRL2,ITGA7,ZDHHC7,LTBP2,ATP1B3,TMEM120A,AKIP1,SEMA3A,CDAN1,CCNB2,IFI6,CTBP1,RAD21,NF2,P3H2,TP53,P2RX7,ERBB2,RASGRP3,BAHD1,STIL,EMP2,BCAP31,TMSB15B,SYTL2,PER2,TTC21B,PDGFA,ATP6V0B,KMT5C,SRPX,TACC2,SRR,BCL6,PLK4,ZDHHC23,CDH3,ESPN,LMAN1,SULF2,CTH,PPIF,SIRT1,CLCN3,TIMP2,MBP,TCEB2,AKT1,FIGNL1,S100A4,CDC20,MYL12A,DAG1,TAPBP,RTN4RL1,IDE,RBL1,PSMD3,PTK7,ADAMTS14,CHMP4B,XRCC3,EFNA5,SYT13,ARHGAP4,RPL22,CNEP1R1,COPG1,ZC3HC1,FAM134B,BIN1,COL9A3,PINK1,PACSIN2,TRAPPC10,KLHL13,CTSB,CDCA8,ERCC6L,ERI2,PSMD10,HMGN3,CRABP2,AIP,H1FX,NRP2,GBX2,ZDHHC21,CEP97,CDK16,SGK1,TRIM21,BUB1,HMGCL,ABCD1,CAMK2G,P2RX4,HES1,FBLN5,RHOA,HMGN5,PSMB4,NR3C1,CRB3,AMFR,STMN3,COL7A1,CAPNS1,BCAR1,BBS2,BORA,BCL10,DDX23,PRDX4,SERPINA1,FAT4,FGF18,PGRMC1,PPP2R3C,PKD2,SPCS3,UBE2C,TBC1D4,ARHGEF4,DIS3L,GOLGB1,SUN1,GAA,CFAP74,SSH1,HSPG2,ATP8A1,GATA3,PSME1,PLXNA1,CCNB1,SEPT4,OAT,FAM101B,CENPN,PICK1,PAK6,TYMP,CTGF,ELMO2,KCNS3,PIK3CA,TFG,PACSIN1,XKR8,SPATA18,ACVR1C,PBK,CASP9,CDYL,BNIP3L,SLC35C1,AGO4,KIF13A,TNS1,PIF1,AURKB,CCNF,MCFD2,ARHGEF26,ULK2,PRIM1,SLC25A4,AREG,PLK2,GNPTAB,PPP2R4,PRDM5,BMP1,UNC5B,F2RL1,RTN3,FGD1,SEMA6B,KLF2,RECQL,MRPL44,INPPL1,DHPS,TBC1D1,PRKAA1,KIF23,SLC1A3,APBA1,PSIP1,MECOM,CALR,DOPEY2,ITGA3,CYR61,SNX18,RPL39,MSH2,PRKG1,TNFRSF12A,CACNA1D,PIKFYVE,CTSD,MAST4,KCTD3,SYTL3,TSPAN33,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,KCNJ12,GCC2,CEP89,B9D2,CALM1,ANO6,WHSC1,EPHA1,ATP8B3,KDM3A,ANTXR1,JADE2,NFIB,RASA1,STX3,FAS,DGKH,MMP15,PLEKHH2,PRKAG2,FAM64A,WDR19,ZDHHC20,MATN2,ARAP1,FAM83D,FGD6,SFMBT1,NR4A2,KLK7,CABIN1,EFNA1,HOOK1,EHD1,ELK4,SPRED1,KIF3C,SLC2A4,CEP70,DLGAP5,TCTN2,REPS2,ST14,TRIP10,RPS6KA1,IQGAP1,NDRG1,SUZ12,FTH1,KCTD12,BLCAP,BCL2L1,AIFM2,DDR1,MNS1,ZFYVE9,APLP2,CCNA2,TNPO2,DAB2IP,PDE4D,EPHB4,FLOT2,GPX4,SEMA3B,ATG4D,SEC23A,COG2,TMEM43,CAPN6,DMTN,TEP1,COX11,PRKCQ,SLC11A2,ATP1B1,PKMYT1,PYGO1,ITPR3,AKR1E2,ALCAM,H2AFV,ATP10D,FZD7,NIN,CEP162,ZMPSTE24,EPHA10,FYN,JAK1,DDOST,STK26,TRIOBP,KLF5,NRG1,RAB29,MLKL,COBL,CBX7,ATMIN,PRKAR1A,MRPS9,WASF3,PLSCR4,ATP9A,CENPI,EPS8,CDCA3,NES,PLD2,SPDL1,SPR,EFNB1,FGF19,SIX4,RND1,SLC25A36,CKAP5,SNTA1,PTEN,CENPJ,PRC1,CD9,ATP8B1,ERCC2,ERBB3,MAP3K7,SPRY2,MSH6,NCOA2,SMC4,FARP2,PDGFC,RASGRF1,ZWINT,SHMT1,B3GNT2,CASK,ARHGEF28,PAPD7,FURIN,VAMP3,C1GALT1C1,DIAPH2,YES1,KIF11,CRTC2,DCTN6,FGFR2,PRDX3,RYK,SERPINB5,GRIN2D,GPER1,WDR62,NCAPG2,ARSB,ESPL1,OCLN,USP16,RGMA,JARID2,EMX1,LTBP1,CASP3,UGT8,FAF2,ST13,MPP5,KIF2C,TAF6L,CACNB4,MAP1LC3B,DNER,SH3KBP1,ZFYVE16,RAB15,LRRC6,CDKL5,DPYSL2,CEP78,DLG1,CAPG,TRPC1,SUN3,KIF22,RAB20,ASH2L,RP2,MYH14,NFU1,CTTN,BTBD3,IL1RAP,RASGRP1,CYP1B1,OLFML2A,ATL1,SOD1,CENPA,ASXL1,SYNE3,STRIP2,FOPNL,RNF165,ARHGDIB,MRPS18A,PTGFRN,MRPS36,TYSND1,IARS2,PSMC1,CAPN1,NR2C2,PIFO,ARAP3,PPP1R12A,SERPINE2,PEX6,BVES,ETV5,ASL,ATP6V1E2,CALM3,ADAMTSL4,DUSP5,SPP1,LRRN2,PFKL,OCRL,KCNN4,COL6A1,PRKCI,FXYD5,SRP54,LIMCH1,KNTC1,ZRANB1,SLC12A2,ALS2CL,CCDC88A,SNX7,HP1BP3,VWA1,HMG20B,FBXO8,NUBP1,RANBP9,EGFR,FECH,TSC1,ONECUT1,INSR,UTP14C,TMEM30A,PAPD5,CDCA5,RAB31,PITPNA,SHROOM2,JAK3,COL16A1,RARG,SNX30,KLF7,DRD1,FBXW5,GAS2L1,LZTFL1,DYNLRB1,SORBS1,SPC25,SLC2A8,PSME2,HDAC11,SOD2,COL18A1,MRAS,TDRKH,ZMYND10,PATL2,MICALL2,KCTD9,SAP130,SS18,KCTD15,ARTN,SETDB2,COX14,ZDHHC12,KIF14,FRYL,REEP1,SMO,RPN2,EPB41L4B,NFKB2,F2R,LOXL1,HSPA2,FRS3,CKS2,CHP1,SOAT1,GCA,TAF5,BAG4,MRPS35,ERBB2IP,CD40,CDC25C,KCTD2,ARHGAP35,JADE1,HSF4,ALDH5A1,PEX2,SPTBN5,PLXND1,SGOL1,REEP4,ABCA1,LIFR,PPP2R2D,CBX4,FBLIM1,GCLM,SORT1,TSPAN15,ARHGEF11,SH3D19,SHPRH,CIT,ARHGEF7,FRMD6,POC1B,LRP4,TGFBR1,COL4A5,HMGXB4,ITGA2B,HDAC9,SAC3D1,KIF5B,TOP2A,ADORA1,TAF1B,LLGL2,A4GALT,BMP7,TOX2,H2AFY,IQGAP3,RPGR,MYO5A,SUN2,ADAM17,RAB3B,CENPC,CFAP46,ASPM,GCLC,POLD3,MPV17L2,SPAG1,MAP1B,LEMD2,CTSL,CASP7,SWAP70,RND3,CTSV,SPINT2,RAP2C,CSGALNACT1,TADA2B,ARRB1,GEM,ATP6V1C1,ZMIZ1,PLOD3,CEP41,L1CAM,ABCG1,NGEF |
| 6.133e-11 | -23.51 | LIU_CMYB_TARGETS_UP | MSigDB lists | LIU_CMYB_TARGETS_UP | 159 | 56 | 17758 | 2588 |
ZNF395,NQO1,SOX9,FAM134A,ARL4C,GMCL1,ISYNA1,TP53I11,PHLPP1,NUCB2,OAT,CA8,MAP1LC3B,DNAJB9,SH2D4A,H1FX,SAC3D1,IL17RB,ADD3,RPS6KA2,WDR44,TACC2,LHX6,DLG1,KCNS3,ALDH7A1,ECE1,CITED2,TSPAN1,TIPARP,MPHOSPH9,EPHX1,NAGPA,TGIF1,MMD,CTNNAL1,HSPA12A,SAT1,LITAF,FHL2,BNIP3L,EMP3,AK4,PRKAR2B,ESYT1,PCTP,CRISPLD2,STK17A,CTNS,RBM47,DHRS2,NAB2,RAB11FIP1,SLC31A2,TOB1,ACOT7 |
| 6.133e-11 | -23.51 | HALLMARK_APOPTOSIS | MSigDB lists | HALLMARK_APOPTOSIS | 159 | 56 | 17758 | 2588 |
CASP3,BMF,ADD1,ENO2,LGALS3,IGFBP6,DAP,DNAJC3,BIK,TAP1,XIAP,SOD2,ERBB2,IL18,BCL2L1,EGR3,SLC20A1,BCAP31,LMNA,IER3,TOP2A,CCND1,BMP2,WEE1,BTG3,TGFBR3,CTNNB1,TIMP1,FDXR,BAX,CDKN1B,TNFRSF12A,ERBB3,F2R,PLCB2,CTH,GPX4,SOD1,TIMP2,IFITM3,SAT1,CASP9,BNIP3L,CASP4,RHOB,BCL10,FAS,TIMP3,CASP7,DNM1L,H1F0,MADD,RNASEL,HSPB1,AIFM3,IRF1 |
| 6.501e-11 | -23.46 | macromolecule modification | biological process | GO:0043412 | 3008 | 566 | 16441 | 2455 |
TRIM24,TRIM5,RET,XIAP,FBXO2,NRG2,IL18,MORF4L2,BARD1,SPSB1,GRM5,CALM2,DAPK2,WEE1,PSMD1,TGFBR3,MUC4,UBE2T,FUT1,CRY2,PPP1CA,PIK3CD,TIPARP,CPE,MGAT5,APOBEC3G,NEK4,FBXL16,RNF11,LOXL2,ICMT,RNF19B,ARF4,PIAS3,LIMK1,MYLK,NOD2,MAP3K11,HDAC1,RNASEL,ITPKA,GAB1,NUAK1,SOX9,ZNRF3,MERTK,RABGGTA,ATG4A,MARCH8,FBXO7,NEK2,FBXL14,MAP3K9,USP38,USP1,ALPK1,STT3B,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,TTLL1,PPP6R1,NAGPA,MAPKAPK3,STAT4,ERO1A,SHARPIN,ELK1,ILK,PSMA4,STK17A,PTPRF,NCOA3,FNTA,MTFMT,SETD3,TEX30,AURKA,STK39,B4GAT1,ALG2,CFAP20,NUP58,RPS6KA3,RUSC1,EGLN1,DMPK,MTM1,GALNT12,INPP5D,WDTC1,TESK2,MAPK4,GRK6,PRKACA,CCND1,MUC16,RNF220,SP100,RASGEF1A,RNF169,SSH3,RIPK2,APOBEC3D,PTPN9,XRCC6BP1,IRS2,CDK19,AXL,WWTR1,TRABD2A,MAPK12,TAOK2,MAN1A2,DCAF7,TRAF2,CCM2,PDIA3,CTSZ,PKN1,TSPAN17,DTX3L,FUT2,IRAK1,CTSC,ARSG,ALG13,MGAT4A,WWP1,MAPK11,RAG1,CRTAP,RAPGEF2,PIK3R1,DUSP23,EIF5A2,NUB1,GRIN1,UBE2A,PIM3,NEURL1B,TXK,GALNT3,DCAF10,BTG1,PLOD2,ATXN7L3,ACVRL1,DBI,PPM1H,ITGAV,NUP37,WDR45B,PHC1,UNKL,TNK1,TRIM2,PPM1J,CUL4B,EPHA4,SUDS3,MGAT5B,HDAC6,PDGFB,PIGL,SPTB,NUP210,RPS6KA2,SHC3,P4HB,MKRN3,PSMC2,PASK,DUSP10,PLK1,MARK1,PTPN18,PRKRA,CDK1,TRUB1,VCP,KDM4D,TRIM9,MSL1,WIPI1,P4HA2,DOLPP1,TTC9,POMT1,PRKAA2,LMTK3,RASA2,UBASH3B,PSMD7,ADCK5,RAB6A,B4GALT4,PGAP1,B4GALNT1,BMP2,UBE2Q2,IGF1R,CMTR2,PAK2,MDFIC,PIM1,PSMA5,USP31,TESK1,MGAT4B,KBTBD8,STRADB,EIF2AK1,PDK3,ZDHHC3,G2E3,NMT2,CDK5R1,MAPKAPK2,PHLPP2,KBTBD2,P4HA3,ZDHHC7,CTBP1,RNF146,USP43,RAD21,P3H2,CTDSPL,ERBB2,P2RX7,RASGRP3,KBTBD11,PER2,CDK14,PDGFA,KMT5C,PPME1,ZDHHC23,PLK4,LMAN1,EGLN3,CTDSP2,CTH,SIRT1,PPIF,TCEB2,AKT1,CDC20,PTGER4,PTPRJ,ATP1A1,PSMD3,PTK7,STK38,ST3GAL1,POMGNT2,ZC3HC1,CTDSP1,MAN2B2,CMAS,PINK1,DYRK3,TRAPPC10,KLHL13,TAB3,GNE,PSMD10,PPP2R3A,ZDHHC21,CDK16,UBE2J1,SGK1,TRIM21,BUB1,SYK,CAMK2G,GCNT1,DUSP1,MLEC,PSMB4,AMFR,PLAUR,COL7A1,PELI3,MAPK8IP1,USP6,PRDX4,FUCA1,SERPINA1,SCG2,FGF18,UBE2C,HIPK3,ACVR1,SSH1,CUL1,PSME1,NANS,CAMK1D,PJA2,CCNB1,PICK1,ASPHD2,PAK6,PALD1,IL31RA,PIK3CA,MARCH2,TFG,METAP2,ACVR1C,PBK,CDYL,GALNT7,SLC17A5,AURKB,MCFD2,CCNF,POR,ULK2,SGPP1,AREG,GNPTAB,SH2D3C,PLK2,PPP2R4,PRDM5,MAPK13,TRAF5,CDK17,DHPS,PRKAA1,HERC6,TNFRSF19,BMP2K,SH3RF2,CALR,ZNRF2,PPP4R1,OPN3,PRKG1,ADCK2,DAPK1,TPST1,MAST4,TMED2,TRAK2,SOCS5,GFPT1,PIGC,B3GNT7,DDB2,MMD,CALM1,PTPRH,WHSC1,EPHA1,JADE2,KDM3A,FBXO10,RASA1,MMP15,PRKAG2,PELI2,CSNK1G1,ZDHHC20,PIAS2,AGBL5,CDK18,MAP3K5,IFIH1,NRBP1,ELK4,SPRED1,DLGAP5,SUZ12,RPS6KA1,RNF182,DDR1,FLT3,ART5,EPM2A,DOK4,FICD,DAB2IP,EPHB4,PHKA2,ATG4D,SEC23A,PRKCQ,PKMYT1,CBL,B3GALNT2,ASB13,EPHA10,FYN,DDOST,JAK1,STK26,TRIOBP,KIAA1804,PPP1CB,NRG1,MLKL,B4GALT3,AREL1,OTUD5,CDCA3,HERC5,CBLL1,APOBEC3H,FBXO6,FGF19,WWP2,RNF128,MGAT1,PTEN,FUT8,SGK3,ERBB3,ERCC2,MAP3K7,TRIM62,NCOA2,RASGRF1,B3GNT2,CASK,FURIN,PARP4,FBXO9,C1GALT1C1,UBAC1,YES1,FOS,ARSK,CRTC2,CDK5RAP1,PRDX3,FGFR2,RYK,GRIN2D,LRRK1,ARSB,MELK,USP16,CCNC,CAMKK1,UBE2Z,UBE2Q1,TAF6L,TRIM68,ADPRHL1,CDKL5,DLG1,ASH2L,PTPRE,STK35,RASGRP1,TRIM8,ASXL1,USP18,ITCH,RNF165,ROR1,STK17B,ADRBK2,MAN2A2,NEIL1,FASTKD1,UEVLD,CAB39,PPP2R5D,PSMC1,CPPED1,PPP1R12A,ASB9,ASL,CALM3,TEC,PHLPP1,ADAMTSL4,DUSP5,B3GALNT1,OTUD1,TYW3,FAM20C,PRKCI,NPTN,ZRANB1,GAD1,MDFI,GYLTL1B,PDIK1L,EGFR,GNAS,NUDT16,INSR,UAP1,PLPP3,DCUN1D1,ALPK3,CTSA,YOD1,JAK3,FBXW5,LMO7,PAX6,IL15,PSME2,HDAC11,TDRKH,EXT2,SAP130,SETDB2,ZDHHC12,RPN2,LOXL1,F2R,SCYL3,SEPHS1,FRS3,MAP3K3,TAF5,PTPRU,DUSP4,CDC25C,MAP3K6,SOCS3,HSF4,JADE1,PEX2,SPTBN5,ABCA1,CBX4,CIT,SHPRH,TGFBR1,NOTUM,TRMT2B,TRIB2,SBF1,POMGNT1,HDAC9,ADRBK1,A4GALT,TRIM3,IQGAP3,SLC35A1,B3GALT6,RAB3B,DCAF6,RC3H2,RUNX3,KLHL2,TRIM69,DTX4,UBE2D2,TADA2B,ARRB1,OTUB2,GLB1,CEP41,PLOD3 |
| 6.602e-11 | -23.44 | neurogenesis | biological process | GO:0022008 | 1664 | 341 | 16441 | 2455 |
SSH1,RET,HEXB,MCOLN3,GATA3,NRG2,PSME1,PLXNA1,CAMK1D,NCS1,PICK1,GRM5,CALM2,TP73,CDKN2C,WEE1,PSMD1,DNM2,SEMA3G,PACSIN1,ZBTB18,TIAM1,TFAP2C,ULK2,ARF4,PLCG1,AREG,LIMK1,PLK2,NKD1,UNC5B,ITPKA,ARF6,LZTS1,SEMA6B,SCN5A,CDKN1C,SOX9,SLC1A3,CALR,RAC2,ITGA3,FRY,FLRT3,MEGF8,PRKG1,SORL1,TNFRSF12A,CACNA1D,NCAM1,DGKG,RIMS2,MMD,CALM1,DCHS1,KIF20B,EPHA1,ILK,DPYSL4,NFIB,PSMA4,STX3,RHOB,RASA1,PTPRF,SEMA4D,HTT,MATN2,NAB2,CLMN,AURKA,NR4A2,EFNA1,B4GAT1,GDF11,ARPC2,NDE1,TRPC3,RPS6KA3,EHD1,SPRED1,FOXO6,NDRG1,IQGAP1,RPS6KA1,CDH1,DACT1,DAB2IP,EPHB4,ACSL4,RASGEF1A,DLG3,ETV4,SEMA3B,SSH3,CAMSAP3,COL6A2,FZD4,SLC11A2,PRKCQ,ALCAM,FZD7,NFIX,EPHA10,IRS2,FYN,JAK1,AXL,SLC9A6,SIPA1L1,RAB29,NRG1,RGS14,COBL,WASF3,CTHRC1,FARP1,SDC4,FLOT1,PBX3,PLPPR4,SPR,EFNB1,FGF19,SIX4,TEAD3,RND1,NEO1,ANK1,IGSF9,PTEN,KNDC1,CD9,BAX,ATP8B1,ERBB3,ERCC2,GFI1,ITM2C,S100A6,FARP2,RASGRF1,TGIF1,B3GNT2,ARHGEF28,FMN1,TACC1,RAPGEF2,GRIN1,YES1,ABLIM2,CDK5RAP1,CNTNAP1,PITX2,PROM1,FGFR2,NR4A3,RYK,GRIN2D,GPER1,ITGAV,FZD5,WDR62,ARSB,SHOX2,FOXA1,RGMA,MYL9,CASP3,EMX1,UGT8,AGRN,CUL4B,EPHA4,ARFGEF1,MPP5,DNER,PDGFB,CACNB4,TMC1,SPTB,PLS3,RPS6KA2,CTNNB1,CDKL5,SHC3,DPYSL2,IL6ST,PSMC2,DLG1,DUSP10,TRPC1,NTN4,MYH14,CTTN,BTBD3,RASGRP1,ATL1,SOD1,MARK1,CELSR2,RNF165,EZR,KLK6,CDK1,RHEB,IRX3,DPYSL3,HS6ST1,GPRC5B,MAP2,PSMC1,MYL12B,GRN,USH1C,RUNX2,SERPINE2,RASA2,ETV5,PSMD7,CALM3,RACGAP1,CNTNAP2,DUSP5,BMP2,RB1,SPP1,VASP,IGF1R,LRRN2,GATA2,KIF13B,PAK2,COL6A1,PRKCI,NPTN,NTN1,WNT3A,PSMA5,CCDC88A,DPYSL5,RGMB,HMG20B,TCF7,SCRIB,RANBP9,CDK5R1,EGFR,FA2H,CSF1,PLPP3,TMEM30A,PITPNA,SEMA3A,JAK3,KLF7,DRD1,PAX6,NF2,PSME2,HDAC11,TP53,ERBB2,RASGRP3,MICALL2,PHLDA1,PER2,PDGFA,ARTN,TACC2,LMO4,FRYL,LHX6,BCL6,SMO,TWIST1,DIXDC1,NOTCH3,FRS3,TIMP2,AKT1,CDC20,MYL12A,DAG1,ARHGAP35,RTN4RL1,PTPRJ,BHLHB9,PTK7,PSMD3,PEX2,SPTBN5,EFNA5,PLXND1,LIFR,POMGNT2,CTDSP1,BIN1,COL9A3,ADGRG1,ARHGEF11,ARHGEF7,CIT,LRP4,PSMD10,TGFBR1,COL4A5,JAG2,CRABP2,PPP2R3A,NRP2,ITGA2B,GBX2,HDAC9,KIF5B,CDK16,LLGL2,MYCL,BMP7,KIAA0319,TFAP2A,SGK1,RPGR,TLE6,CAMK2G,FAM134C,HES1,RHOA,PSMB4,WNT10B,ASPM,STMN3,RUNX3,MAP1B,LEMD2,FAT4,FGF18,PGRMC1,SOX8,L1CAM,NGEF |
| 7.029e-11 | -23.38 | catalytic activity | molecular function | GO:0003824 | 5611 | 975 | 16491 | 2452 |
ACACB,KLK10,TRIM24,AK7,AASS,TRIM5,PNPLA2,RET,HEXB,XIAP,FBXO2,SMARCAL1,CCNO,DHX8,LGI3,LACTB2,ISOC2,DPP8,KIF26A,CA8,BARD1,DAPK2,WEE1,PSMD1,TGFBR3,UBE2T,DNAH6,CYP2S1,ALDH1A3,RDH14,ATP13A3,FUT1,DNM2,TUBG1,CRY2,TINAGL1,PIK3CD,ACOX2,PPP1CA,CPE,TIPARP,APOBEC3G,MGAT5,ERAP2,TUBA4A,NEK4,SMARCA2,FBXL16,TNIP1,RNF11,CDA,LOXL2,F12,ICMT,RNF19B,PNKD,CYP4F3,ARF4,GINS4,PIAS3,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,MYLK,MAP3K11,HDAC1,RNASEL,ITPKA,ARF6,PDPR,ALDH6A1,NUAK1,CYP2J2,SOX9,RAB23,ZNRF3,COX6C,MERTK,RABGGTA,ATG4A,GNS,MARCH8,RAC2,DNPEP,ATP5H,FBXO7,NEK2,FBXL14,PCYOX1,MAP3K9,USP38,USP1,ALPK1,STT3B,MAPK7,MOXD1,DGKG,MYLIP,NDUFA12,PHKG2,TTLL1,MCCC2,EPHX1,NAGPA,UFD1L,KIF20A,MAPKAPK3,ERO1A,KIF20B,MEST,ILK,DPYSL4,SPTLC2,GOLT1A,PSMA4,GNA11,RHOB,CYB5A,DCP2,DHX32,STK17A,PTPRF,NAAA,NCOA3,FNTA,MTFMT,SETD3,APMAP,TEX30,DGAT2,AURKA,MDH1,STK39,B4GAT1,ALG2,RPS6KA3,DMPK,XDH,ADAMTS16,EGLN1,MTM1,PAPSS2,NQO1,TUBB4B,LFNG,GALNT12,INPP5D,RHBDL3,ETNK1,TESK2,PRSS22,MAPK4,GRK6,MGST2,PRKACA,MOCS1,APPBP2,CDS1,CCND1,RNF220,XYLT2,ENPP5,ACSL4,ARL4D,DLG3,RAB27B,RNF169,MX1,ENPP4,SSH3,ERMP1,APOBEC3D,RIPK2,AGPS,PFKFB2,PTPN9,SAT1,VPS4B,HTATIP2,PXYLP1,RAB38,XRCC6BP1,ALDH3B1,CDK19,AXL,INPP4B,PNPLA6,TRABD2A,PDXK,GEN1,ISOC1,MAPK12,GALK1,TAOK2,GCAT,PARP14,MAN1A2,BACE1,TRAF2,OSGIN2,PDIA3,CTSZ,PKN1,PLPPR4,GSTP1,IFT27,TSPAN17,PDIA4,SGPL1,DTX3L,CAPN2,DIRAS3,FUT2,IRAK1,SLC27A6,CTSC,ARSG,TMEM62,ALG13,MGAT4A,FAM20B,FDXR,KLC3,ECI2,ADAM15,WWP1,MAPK11,AK3,RAG1,TMX1,PARP9,OPLAH,ADAMTS2,NUDT8,ELOVL3,DUSP23,UBE2A,DBR1,AK4,BLVRA,PIM3,NEURL1B,TXK,GALNT3,PLOD2,ACVRL1,PLA2G15,PPM1H,HMGA1,CENPE,CMPK2,CYBRD1,ACOT7,TLL2,UNKL,TNK1,TRIM2,GNPDA1,PPM1J,CNOT8,CUL4B,EPHA4,SUDS3,MCCC1,PHOSPHO1,GALM,MGAT5B,CDIPT,HDAC6,PIGL,INPP5E,RPS6KA2,PCNA,ENTPD4,P4HB,MKRN3,ARL1,PAPSS1,PSMC2,DDHD2,PASK,PAPL,ABCA2,DUSP10,DDX59,PLK1,MARK1,PTPN18,C12orf65,CCBL2,ERP44,ARFRP1,KLK6,IDH1,CDK1,TRUB1,VCP,RHEB,KDM4D,DPYSL3,TRIM9,PLCH1,HS6ST1,PI4K2B,AGPAT2,P4HA2,DOLPP1,PIK3C2B,TTC9,POMT1,RRAGD,HS6ST3,PRSS8,PRKAA2,LMTK3,PARP12,UBASH3B,ASAH1,ADCK5,RAB6A,B4GALT4,DHRS3,PGAP1,RSAD1,MYO5C,B4GALNT1,BMP2,UBE2Q2,IGF1R,KIF13B,CMTR2,PAK2,AHCY,PIM1,FAR2,PLCB2,ALDH3A2,PSMA5,ABCC1,CYP26B1,DPYSL5,CHSY3,USP31,TESK1,MGAT4B,STRADB,KBTBD8,EIF2AK1,PDK3,ZDHHC3,G2E3,NMT2,CDK5R1,DHDH,MAPKAPK2,FA2H,OTUD6B,PHLPP2,KBTBD2,PRPS2,P4HA3,ZDHHC7,PLD1,ATP1B3,CTBP1,RNF146,USP43,UGP2,P3H2,TMX4,XYLT1,CTDSPL,DGKA,ERBB2,LPIN3,KBTBD11,CYP26A1,CDK14,ATP6V0B,KMT5C,PPME1,PLCG2,SRR,PLK4,ZDHHC23,VAT1,GYS1,GLB1L2,OAS3,EGLN3,MINPP1,FAR1,CTDSP2,GM2A,CTH,SULF2,PPIF,CPD,SIRT1,AKT1,FIGNL1,ACO1,ATP13A2,PTGS2,DUOX1,DNAJC10,TAPBP,ATP1A1,IDE,PTPRJ,PAFAH1B3,ABHD12,PTK7,STK38,MMP17,ADAMTS14,MAOA,XRCC3,C1orf43,LTA4H,ST3GAL1,AIFM3,POMGNT2,NDST3,CTDSP1,MAN2B2,CMAS,PINK1,DYRK3,KLHL13,CTSB,SCD5,HAL,BLVRB,GNAL,GNE,ERCC6L,ERI2,CHAC2,DSE,LBR,NRP2,ZDHHC21,CDK16,ALPP,GTF2F2,UBE2J1,SGK1,TRIM21,BUB1,ALDH7A1,ABCD1,HMGCL,SYK,CAMK2G,ATP2B1,GCNT1,FAH,DUSP1,RHOA,PSMB4,GUSB,AMFR,DPP9,GGH,CAPNS1,PELI3,TXNDC11,RNPEP,DGKE,SCRN2,DDX23,PRDX4,USP6,CNOT2,FUCA1,DDAH1,NEIL3,NAT1,ACADM,SPCS3,UBE2C,PTGES,SAT2,HIPK3,DIS3L,CFAP61,GAA,TXN,ACVR1,SSH1,TMEM86B,ATP8A1,KLC2,TAP1,CUL1,PDGFRL,NANS,CAMK1D,PLA2G16,CCNB1,PJA2,SEPT4,OAT,CHST2,PICK1,ASPHD2,PAK6,HELZ2,TYMP,CYP1A1,PALD1,POLL,STEAP2,AOX1,PIK3CA,MARCH2,SMYD5,METAP2,LOC81691,TMEM68,KIFC2,ACVR1C,PBK,CDYL,CASP9,MGAM,KIF13A,AURKB,PIF1,GALNT7,TP53I3,POR,ULK2,RAB2B,PRIM1,SGPP1,KDSR,GDE1,PLK2,PTER,GNPTAB,PPP2R4,PRDM5,BMP1,DHTKD1,MAPK13,WBSCR27,TRAF5,DLAT,DDX58,RECQL,INPPL1,MRPL44,CDK17,DHPS,TMEM55B,DGKQ,ADO,PRKAA1,KIF23,NDUFA4,ISYNA1,HERC6,PDXDC1,KIAA1161,BMP2K,SH3RF2,ZNRF2,PPP4R1,BDH1,CTPS1,MSH2,ADCK2,PRKG1,DAPK1,TPST1,PIKFYVE,CTSD,MAST4,DNAI1,SPATA20,PIGC,GFPT1,FADS2,PRODH,PMPCB,B3GNT7,DDB2,QSOX1,KLK5,MMD,PRSS23,ADCK3,LPGAT1,PTPRH,PIP4K2C,WHSC1,PYGL,ATP8B3,EPHA1,PKM,KDM3A,FBXO10,GLT8D2,PDE11A,DGKH,MMP15,NT5C2,PRKAG2,FAAH,DCK,PELI2,CSNK1G1,ZDHHC20,MPP2,PIAS2,AGBL5,CDK18,SAMD8,KLK7,MAP3K5,IFIH1,NRBP1,PLA2G4A,KIF3C,CAPN12,DLGAP5,ST14,RALBP1,SUZ12,RPS6KA1,ATP2C2,RNF182,FTH1,AIFM2,DDR1,NUDT12,FLT3,CYP39A1,GNB2,TMPRSS4,ART5,EPM2A,ZFYVE9,APOBEC3B,CD46,RALB,FICD,RNASEH2A,PDE4D,EPHB4,PHKA2,LGMN,SULT2B1,NAGA,ATG4D,GPX4,MYO5B,CAPN6,CYB5R2,PANK1,TEP1,COX11,KIF1C,PRKCQ,ATP1B1,PKMYT1,RAD17,AKR1E2,CBL,B3GALNT2,ATP10D,ZMPSTE24,PRDM11,EPHA10,AMZ2,FYN,JAK1,DDOST,ACYP1,ACAD10,STK26,HAGHL,KIAA1804,PPP1CB,SLC27A1,RAB29,HS3ST3B1,MLKL,ZC3H12B,B4GALT3,AREL1,SLC27A3,OTUD5,NUDT6,ATP9A,ARL4C,HERC5,CBLL1,PLD2,APOBEC3H,CYB561,FBXO6,DNAH3,SPR,PNPLA5,COX7A2,WWP2,RND1,RNF128,GNB5,OXCT1,MGAT1,PTEN,FUT8,SGK3,ATP8B1,ERBB3,ERCC2,MAP3K7,CNOT6L,TRIM62,NCOA2,OSGIN1,MSH6,PCCB,CASK,ALDH2,SHMT1,B3GNT2,LONRF3,PAPD7,MPP1,FURIN,PARP4,C1GALT1C1,FBXO9,YES1,ARSK,KIF11,GPLD1,CDK5RAP1,ACADSB,FGFR2,PRDX3,ABCB1,RYK,ERAP1,PGM2L1,LRRK1,ARSB,ESPL1,OCLN,MELK,USP16,JARID2,CCNC,NMRK1,CASP3,LTBP1,UGT8,CRYM,ABHD17B,CPT2,CAMKK1,EPHX4,UBE2Z,UBE2Q1,VARS2,TAF6L,KIF2C,ERP29,ECI1,TRIM68,TSEN34,CHPF,ABCD4,ADPRHL1,RAB15,METTL7A,CDKL5,DPYSL2,IMPAD1,DLG1,AKR1B1,KIF22,ASH2L,RAB20,MYH14,TECR,PTPRE,STK35,CERS2,CYP1B1,TDP1,ATL1,SOD1,TRIM8,LAP3,ITCH,USP18,RNF165,ARHGDIB,ROR1,MRPS36,TYSND1,ADRBK2,STK17B,SEC14L2,EDNRA,MAN2A2,NEIL1,FASTKD1,HPSE,UEVLD,DHRS13,IARS2,GLA,CHPT1,RAP1GAP,PPP2R5D,PSMC1,CPPED1,CAPN1,PCSK5,FAM213B,PEX6,PYROXD2,ELOVL7,ASL,ABCG2,ATP6V1E2,TEC,PHLPP1,ADAMTSL4,DUSP5,QSOX2,OTUD1,TYW3,B3GALNT1,CES2,CA2,FAM20C,PFKL,OCRL,PRKCI,SRP54,NPTN,ZRANB1,NCEH1,ACAD8,GAD1,DESI2,OXR1,GYLTL1B,PDE5A,PDIK1L,AMDHD1,STEAP1,EGFR,GLCE,GNAS,FECH,NUDT16,INSR,UAP1,PLPP3,PAPD5,RAB31,ALPK3,YOD1,CTSA,KIF12,JAK3,LMO7,DYNLRB1,PAX6,HDAC11,SOD2,ABCG4,PDIA5,GMPR,MRAS,EXT2,SAP130,SETDB2,CYP4F11,ZDHHC12,KIF14,RPN2,STEAP3,GOT1,ECE1,APIP,ETHE1,LOXL1,PDIA6,SCYL3,SEPHS1,MAP3K3,SOAT1,GCA,TAF5,RFK,PTPRU,GLO1,DUSP4,CDC25C,PDHX,CASP4,MAP3K6,ALDH5A1,PEX2,CANT1,CYP2U1,ABCA1,CBX4,KDELC2,GCLM,CDS2,ENO2,SHPRH,CIT,TGFBR1,NOTUM,TRMT2B,POMGNT1,TRIB2,SBF1,NTAN1,HDAC9,KIF5B,TOP2A,ADRBK1,ADORA1,A4GALT,GALNS,ZDHHC13,TRIM3,MYO5A,B3GALT6,PGM1,RAB3B,ADAM17,CFAP46,GCLC,RC3H2,OGDHL,NADK2,POLD3,SPAG1,ENDOD1,CTSL,KLHL2,MARC1,CASP7,RND3,TRIM69,PRCP,DHRS2,CTSV,TADA2B,UBE2D2,DTX4,CSGALNACT1,OTUB2,ARRB1,GLB1,GEM,PLOD3,ATP6V1C1,ABCG1 |
| 7.290e-11 | -23.34 | malignant_melanoma | COSMIC cancer mutations | malignant_melanoma | 16732 | 2500 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,NAGA,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,ENPP1,PLCG1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,RHBDL3,PTTG1,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,TMEM200B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,VPS26A,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,GPR107,REPS2,CAPN12,DLGAP5,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,PAPD5,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 7.774e-11 | -23.28 | TBK1.DF_UP | MSigDB lists | TBK1.DF_UP | 272 | 81 | 17758 | 2588 |
ACVR1,CCDC109B,TMEM184B,NF2,GPR107,TMEM41B,GALNT12,RGS20,CCDC68,TEX2,NUP62CL,ZFYVE16,BTG3,SRPX,RGS3,PASK,CNNM4,CLDN4,PIK3CD,EPB41L4B,MINPP1,DLG3,MYBL1,SNX10,HSPA2,GCA,NRBF2,OSTM1,C3orf52,TP53I3,ATP10D,ABR,OSBPL2,TRAM2,ACYP1,PTK7,WWTR1,KLF11,ARAP3,ENO2,NFKBIE,CRABP2,DUSP5,FZD6,PPP2R3A,SIRPA,TNS3,RB1,IGF1R,OCRL,OPN3,TPST1,MAST4,CAMK2G,IGSF3,FAM69A,TRAK2,GCC2,SLC37A1,PLAUR,CRIP2,VAMP3,PIP4K2C,C1GALT1C1,EMP3,PCTP,STEAP1,STX3,CD83,ENDOD1,IL1R1,NT5C2,BTG1,SERTAD2,CASP7,SWAP70,CCDC6,NETO2,EFNA1,ITGAV,CYBRD1 |
| 8.143e-11 | -23.23 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP | 315 | 90 | 17758 | 2588 |
ARHGAP11A,CCNE2,DLGAP5,FOXM1,PTTG1,RET,KIF2C,BARD1,STIL,FAM46C,CENPN,FANCI,PCNA,CCNA2,UBE2T,CEP78,PLK4,GLB1L2,RNASEH2A,ARMCX6,MYBL1,IL1RAP,SEMA3B,PLK1,PPIF,LOC81691,CELSR2,FIGNL1,SLC39A8,PBK,CDCA2,NUSAP1,AURKB,PKMYT1,ANLN,CDK1,COL12A1,PRIM1,TMEM164,CDCA4,AREG,RBL1,ZNF367,LRIG1,DHTKD1,XRCC3,GLA,CHPT1,E2F8,CENPI,CIT,KIF23,RACGAP1,IL17RB,TFAP4,TOP2A,E2F7,CENPJ,LYPD6,KCNK5,SGK3,PRC1,BUB1,KNTC1,IQGAP3,CTSD,MPHOSPH9,NUP85,ZWINT,ASPM,MICB,MYBL2,CCDC34,GGH,POLD3,KIF11,DHRS2,CDCA5,CDCA7L,FAM83D,E2F1,RAB31,AURKA,WDR62,NCAPG2,UBE2C,CBX5,CCNB2,ESPL1,MELK |
| 8.805e-11 | -23.15 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | 195 | 64 | 17758 | 2588 |
AVPI1,PAPSS2,LGR4,ST14,GALNT12,PPFIBP2,RASGRP3,SLC20A1,BCAP31,ARHGEF10L,APLP2,CAPG,VAT1,STEAP3,NAGA,CYP1B1,LAMP2,TIMP2,RIPK2,LHFPL2,IDH1,TP53I3,TCN2,PLEKHB1,RBM47,MAOA,PLXND1,GLA,APBA2,SLC31A2,SLC27A3,GRN,SORT1,MPZL1,TBC1D1,CD63,BACE1,CTSB,BLVRB,CTSZ,TGFBR1,CRABP2,MERTK,LMNA,SIRPA,TNS3,SPP1,CA2,CTSC,TMEM51,CD9,AHCY,SYK,PDGFC,QSOX1,PYGL,NPC2,FUCA1,LDLRAP1,SLC2A6,RAB31,CTSA,ACOT7,CD33 |
| 8.884e-11 | -23.14 | negative regulation of biological process | biological process | GO:0048519 | 4447 | 796 | 16441 | 2455 |
HECA,ACACB,TRIM24,ADD1,IBTK,GRIK2,TRIM5,PNPLA2,DNAJC3,XIAP,FBXO2,IL18,MORF4L2,SYTL4,BARD1,KIF26A,PHF1,GRM5,TP73,CALM2,CDKN2C,PSMD1,RGS12,TGFBR3,CABP1,DNM2,CRY2,SEMA3G,PPP1CA,TIPARP,ANKRD9,APOBEC3G,SMARCA2,TNIP1,UXT,CDA,TFAP2C,PRKAR2B,LOXL2,F12,PPP1R14C,PNKD,ARF4,ABR,PIAS3,ENPP1,MID1IP1,CAMK2N2,GRID2IP,ANKRD6,LIMK1,TRAF3IP1,NOD2,HDAC1,SERPINB6,TMOD2,RNASEL,ARF6,HSPB1,E2F8,NFKBIE,NUAK1,ITGA6,SOX9,RAB23,ZNRF3,FAM21C,MERTK,LMNA,ELF3,MARCH8,TFAP4,PAIP2B,FBXO7,NEK2,MYDGF,MAPK7,MYLIP,NUP85,SALL4,ERO1A,SHARPIN,FHL2,CALCRL,KIF20B,NPHP3,ILK,TP53INP2,PSMA4,RHOB,PLIN5,NCOA3,ETS2,HTT,SEMA4D,ITPR1,AURKA,CLMN,STK39,GDF11,CBX5,SERPINB1,NUP58,RPS6KA3,XDH,EGLN1,GRHL2,NQO1,LFNG,INPP5D,PTTG1,WDTC1,RGS20,PKP2,PRKACA,APC2,CCND1,CDH1,SP100,DACT1,TAX1BP3,ACSL4,DLG3,CDKN2D,MYT1,ETV4,RNF169,MX1,CAMSAP3,PSRC1,RIPK2,APOBEC3D,FZD4,VPS4B,HTATIP2,SNX12,NFIX,IRS2,PEX5,CORO1C,WFS1,AXL,WWTR1,INPP4B,TRABD2A,RGS14,MAPK12,CTHRC1,TCAF1,FARP1,TNRC6C,NKX3-1,HSP90B1,CKAP2,TRAF2,ANO9,PKN1,ZNF219,ETS1,GSTP1,TIPRL,ICAM1,NEO1,CTNNBIP1,PDCD10,ITGB8,IRAK1,GPC3,CST3,BAX,ADAM15,TMBIM6,WWP1,MAPK11,RAG1,ITM2C,CRTAP,PLSCR1,RAPGEF2,PIK3R1,GRIN1,EMP3,PIM3,PITX2,BTG1,NR1D2,ACVRL1,NR4A3,ITGAV,HMGA1,FHL1,NUP37,OSR1,SHOX2,SRSF9,FOXA1,SIGIRR,TNK1,CNOT8,EPHA4,SUDS3,ARFGEF1,LMCD1,NDRG2,F11R,NENF,TP53I11,HDAC6,PDGFB,SPTB,FANCI,SUSD2,BTG3,NUP210,RPS6KA2,CTNNB1,IL6ST,PSMC2,MITF,ELF5,PASK,DUSP10,TNFRSF18,RGS5,MYBL1,PLK1,THRB,CD55,KCNIP3,ING1,CBX6,EZR,TNFAIP8L1,EAF2,PRKRA,SESN1,CDK1,RHEB,OPTN,IRX3,DPYSL3,TRIM9,KLF12,HOXA9,RAB11FIP1,PRKCDBP,CTNND1,KLF11,RRAGD,PRKAA2,RUNX2,BMF,LMTK3,LGALS3,DNAJB2,UBASH3B,RASA2,PDCL,PSMD7,SORBS3,HES2,FBLN1,DHRS3,CORO1B,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,TBCD,MDFIC,PIM1,NTN1,WNT3A,PSMA5,CYP26B1,STRADB,SCRIB,EIF2AK1,IFIT3,G2E3,CDK5R1,NLRC5,CDAN1,SEMA3A,IFI6,CTBP1,NF2,FOXM1,P3H2,CTDSPL,TP53,P2RX7,ERBB2,BAHD1,STIL,CYP26A1,SYTL2,PER2,IER3,PDGFA,SRPX,LMO4,PPME1,PLCG2,BCL6,CDH3,VAT1,ESPN,NOTCH3,OAS3,CTDSP2,DVL2,SULF2,CTH,SIRT1,PPIF,TIMP2,ERLEC1,AKT1,FIGNL1,CDC20,SERTAD3,PTGER4,C3orf33,DAG1,MYPOP,PTGS2,DNAJC10,PTPRJ,ATP1A1,IDE,RBL1,PSMD3,STK38,CHMP4B,IRF7,ARHGAP4,ZC3HC1,FAM134B,ARFGEF3,CTDSP1,PINK1,PACSIN2,CPEB4,ADGRG1,DAP,CTSB,PSMD10,NKRF,AIP,SH2D4A,FZD6,PPP2R3A,CD109,FOXP2,TFAP2A,UBE2J1,TRIM21,BUB1,HEXIM2,KLF9,FAIM,DUSP1,P2RX4,NFE2L3,HES1,RHOA,HMGN5,PSMB4,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,STMN3,TRIM35,CARD19,COL7A1,PELI3,FXR2,BBS2,MAPK8IP1,BCL10,CD83,PRDX4,CNOT2,BANK1,SERPINA1,TWSG1,SCG2,NMI,E2F1,PKD2,NDFIP1,UBE2C,TBC1D4,PTGES,HIPK3,ZBTB33,PKIA,TXN,PPP4R4,ACVR1,LGR4,TSC22D3,FAM129B,TAP1,CUL1,GATA3,PSME1,CAMK1D,CCNB1,PLA2G16,VASH1,FAM101B,RIC1,PICK1,CTGF,ZFP36,RGS3,IL31RA,FOSB,PIK3CA,IRF2,TACSTD2,ZBTB18,PACSIN1,ACVR1C,PBK,CDYL,BNIP3L,SLC35C1,AGO4,PIF1,AURKB,CCNF,SAV1,SLC25A5,POR,ULK2,AHRR,SLC25A4,AREG,PLK2,TBX1,PPP2R4,NKD1,PRDM5,EIF4EBP2,SERPINI1,SPRY4,UNC5B,F2RL1,LZTS1,DDX58,SEMA6B,KLF2,INPPL1,CDKN1C,HLA-E,PRKAA1,SLC25A27,NOTCH2,SH3RF2,MECOM,CALR,ITGA3,CYR61,PIK3AP1,BHLHE41,VASN,MSH2,DAPK1,PRKG1,SORL1,DLX4,GPR161,TMED2,SOCS5,EPB41L5,QSOX1,MFI2,MICB,CALM1,AMER1,WHSC1,EPHA1,KDM3A,NFIB,RASA1,FAS,AP1AR,SERTAD2,PLEKHH2,PRKAG2,NAB2,ARAP1,PIAS2,SFMBT1,NR4A2,CABIN1,EFNA1,PER3,IFIH1,IRF1,ELK4,SPRED1,TCF25,NLRX1,S100A11,THRA,RPS6KA1,DDIT4L,NDRG1,IQGAP1,SUZ12,CAST,FTH1,CD274,EGR3,BCL2L1,FLT3,ZFYVE9,EPM2A,APOBEC3B,CD46,APLP2,NOV,CCNA2,FICD,CDKN1B,TNPO2,DAB2IP,PDE4D,IFIT1,LGMN,FLOT2,NR2C1,TMBIM1,SEMA3B,DOCK4,CDKN2AIP,DMTN,DRAP1,COX11,PRKCQ,RAD17,PKMYT1,CBL,H2AFV,FZD7,FYN,PPP2R5A,STAT1,TRIOBP,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,AREL1,CBX7,PRKAR1A,OTUD5,IGFBP6,DEPDC1,EPS8,NES,CBLL1,HERC5,PLD2,APOBEC3H,FGF19,ADGRB2,HLA-A,SIX4,WWP2,RND1,SNTA1,E2F7,FAM111A,GNB5,RNF128,PTEN,PPP1R10,CD9,ATP8B1,ERCC2,ERBB3,CITED2,MAP3K7,CNOT6L,GFI1,TTPA,SPRY2,TRIM62,OSGIN1,MSH6,NCOA2,TGIF1,ZWINT,CASK,VAMP3,FURIN,GPLD1,CDK5RAP1,RGS9,TIMP3,FGFR2,PRDX3,TBX18,SERPINB5,GPER1,LRRK1,FZD5,CPEB2,ESPL1,JARID2,CCNC,LTBP1,CASP3,FAF2,ST13,CRYM,ERP29,SH3KBP1,EPCAM,SIVA1,TSPAN6,DLG1,CAPG,ARNT2,CTTN,SLC39A10,PTPRE,CYP1B1,SOD1,CXXC5,TRIM8,ASXL1,ITCH,ARHGDIB,EDNRA,CXXC4,MDK,NEIL1,MADD,CAB39,ADIPOR1,GLA,RAP1GAP,PSMC1,MIIP,ARAP3,PPP1R2,PPP1R12A,SERPINE2,CALM3,PHLPP1,DUSP5,SPP1,PFKL,PRKCI,FNIP1,FXYD5,C10orf54,KNTC1,RFX5,ETV7,MDFI,ELK3,OXR1,HMG20B,PDE5A,NUBP1,RANBP9,EGFR,GNAS,NUDT16,ONECUT1,TSC1,PLPP3,CGREF1,NFKBIA,SH3BP4,EGFL7,YOD1,SHROOM2,JAK3,TOB1,RARG,DRD1,PROM2,GAS2L1,LZTFL1,PAX6,IL15,PSME2,SOD2,COL18A1,IL27RA,TDRKH,OSR2,PATL2,MXD1,SAP130,SVBP,SETDB2,KIF14,FABP6,SMO,ZBTB49,TWIST1,DIXDC1,APIP,NFKB2,F2R,HSPA2,CHP1,BAG4,KREMEN2,PTPRU,GLO1,ERBB2IP,DUSP4,DOCK5,ARHGAP35,SOCS3,JADE1,HSF4,BHLHB9,STAT6,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,MAD2L1BP,LIFR,ABCA1,CBX4,GLIS3,ANXA3,GCLM,SORT1,CIT,ARHGEF7,SERPINB9,LRP4,TGFBR1,AES,NOTUM,TRIB2,HMGXB4,HDAC9,IRF2BPL,TOP2A,SNX13,CARD8,ADORA1,ADRBK1,TAF1B,BMP7,KIAA0319,H2AFY,BRD7,KANK2,MXD3,IQGAP3,ADAM17,WNT10B,ASPM,NR4A1,GCLC,RGCC,MBNL3,RUNX3,NDRG3,LEPR,MAP1B,LEMD2,ARHGAP24,HLA-B,SWAP70,DHRS2,CTSV,SPINT2,RAP2C,ARRB1,SOX8,AHR,CD33,ABCG1,NGEF |
| 9.237e-11 | -23.11 | AMUNDSON_GAMMA_RADIATION_RESPONSE | MSigDB lists | AMUNDSON_GAMMA_RADIATION_RESPONSE | 41 | 24 | 17758 | 2588 |
PLK1,CENPA,PTTG1,KIF23,KIF2C,AURKB,CCNF,CCNB1,CDC25C,CDK1,LBR,CDKN2C,WEE1,CCNA2,PPP2R5A,NEK2,PRC1,AURKA,BUB1,CENPE,CCNB2,UBE2C,ESPL1,CKS2 |
| 9.748e-11 | -23.05 | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 191 | 63 | 17758 | 2588 |
MTM1,REPS2,FBXO2,PBX3,NDUFA4,RASGRP3,PJA2,FLT3,MXD1,SCML1,ZFYVE16,FRY,TM9SF2,UBE2J1,BRD7,OSTF1,NFU1,PIM1,PIKFYVE,WBP4,CLIP2,IL1RAP,CCDC88A,SMC4,SOCS5,LOC81691,PDGFC,CD55,RHOA,NRBF2,LGALS8,SAT1,VAMP3,MGAM,CR2,YES1,PCTP,ZDHHC3,ATP10D,FUCA1,PIAS3,HLA-B,MFAP3L,PRKAG2,JAK1,WDR11,H1F0,CSF1,RAP2C,DBI,PPM1H,RYK,FAM117A,ZDHHC7,CAB39,ADIPOR1,ARPC2,NDFIP1,CHPT1,ANXA11,JARID2,CD33,RRAGD |
| 1.050e-10 | -22.98 | MODULE_52 | MSigDB lists | MODULE_52 | 420 | 111 | 17758 | 2588 |
DLGAP5,HSPG2,EPAS1,NQO1,S100A11,FOXM1,PTTG1,C5orf30,NRG2,CCNB1,SDC1,EMP2,CARD10,CHPF,IER3,EPCAM,CDKN2C,ZYX,WEE1,PCNA,CCNA2,SRPX,PSMC2,DNM2,GOT1,RGS5,IFIT1,RNASEH2A,BTBD3,IL1RAP,CKS2,PLK1,SGCE,TIMP2,CENPA,PFKFB2,S100A4,CDC20,LOXL2,PKMYT1,CCNF,ITPR3,ALCAM,CDK1,DPYSL3,ZMPSTE24,MDK,TRAM2,PLK2,TBX1,WWTR1,BMP1,MAFF,GRN,ANXA3,COL9A3,PCOLCE,ITGA6,EPS8,ETV5,GDF15,PDIA4,M6PR,CKAP5,TOP2A,RAC2,SPP1,ITGA3,CYR61,CTSC,CALD1,CD22,GPC3,FDXR,PPP4R1,IGFBP2,ALDH7A1,CITED2,TMX1,MSH6,IGSF3,HMMR,QSOX1,FADS2,ZWINT,MMD,PLSCR1,PRSS23,LPGAT1,MYBL2,FHL2,EMP3,GGH,MEST,KIF11,PSMA4,STEAP1,CYB5A,PROM1,TIMP3,SWAP70,SERPINA1,PLOD2,RND3,E2F1,UBE2C,CCNB2,ESPL1,OCLN,CSRP2,PKIA |
| 1.070e-10 | -22.96 | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | MSigDB lists | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | 241 | 74 | 17758 | 2588 |
TRIM2,UGT8,SPC25,NDC80,C1orf198,IL13RA1,NUF2,CCNB1,CENPN,IER3,CCND1,UBE2T,PLK4,KIF22,FLOT2,ETV4,TUBA4A,CKS2,PLK1,MBP,FIGNL1,CDC20,NUSAP1,AURKB,DUSP4,CCNF,ANLN,LHFPL2,RBL1,ZNF367,TDRD7,TLE1,SERPINB6,SPRY4,CPPED1,GCAT,CIT,ATP9A,SDC4,ETV5,CDCA8,CDCA3,EFHD2,NES,KIF23,RACGAP1,TRIB2,FZD6,CTNNBIP1,TOP2A,E2F7,SPP1,RNF128,CYR61,SNX18,PRC1,CKS1B,USP1,BUB1,ALS2CL,TRIM62,CTNNAL1,ASPM,VWA1,DPYSL4,MMP15,SLC6A6,RND3,SH3BP4,AURKA,SEMA3A,CCNB2,MELK,ACOT7 |
| 1.088e-10 | -22.94 | glioma | COSMIC cancer mutations | glioma | 16917 | 2520 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,RNF224,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,ALPK1,ZMYM1,MYLIP,KANK3,ULBP2,DGKG,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,PARM1,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,GPR107,CAPN12,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.113e-10 | -22.92 | positive regulation of response to stimulus | biological process | GO:0048584 | 1946 | 388 | 16441 | 2455 |
LAMP1,TXN,ACVR1,LGR4,TRIM5,RET,XIAP,CUL1,NRG2,GATA3,PSME1,IL18,CAMK1D,SEPT4,SLC20A1,CARD10,GRM5,TP73,CALM2,DAPK2,PSMD1,TGFBR3,CTGF,ELMO2,IL31RA,PIK3CA,PPP1CA,PIK3CD,TFG,TNIP1,SH3BGRL,F12,POR,PLCG1,DNM1L,ANKRD6,PLK2,SH2D3C,LIMK1,TBX1,MYLK,NKD1,FAM110C,NOD2,MAP3K11,MAPK13,TMOD2,RNASEL,UNC5B,HSPB1,TRAF5,F2RL1,GAB1,DDX58,CDKN1C,SCOC,THEMIS2,HLA-E,SOX9,PRKAA1,NOTCH2,TNFRSF19,KIAA1161,TFAP4,CALR,RAC2,WDFY1,CYR61,PIK3AP1,MEGF8,MAP3K9,TNFRSF12A,MYDGF,NCAM1,MAPK7,TSPAN33,EEF1D,SOCS5,KLK5,MAPKAPK3,MICB,CALM1,AMER1,ANO6,SHARPIN,PIP4K2C,WHSC1,ELK1,ILK,CYFIP2,PSMA4,STX3,RASA1,FAS,HTT,SEMA4D,PELI2,ITPR1,OSMR,KLK7,EFNA1,GDF11,ARPC2,MAP3K5,CFAP20,IFIH1,TRPC3,RPS6KA3,TMEM173,RUSC1,XDH,SPRED1,LFNG,INPP5D,RPS6KA1,BCL2L1,PRKACA,FLT3,EPM2A,CD46,NOV,ST5,RNF220,RALB,DACT1,DAB2IP,PDE4D,RASGEF1A,LGMN,NR2C1,ENPP4,CDKN2AIP,RIPK2,FZD4,DMTN,PRKCQ,CBL,ITPR3,FZD7,IRS2,FYN,JAK1,CDK19,AXL,KIAA1804,NRG1,ARNT,HSP90B1,NKX3-1,TAOK2,TRAF2,EPS8,BIK,FLOT1,BTN3A1,PDIA3,PLD2,PKN1,TSPAN17,FGF19,ICAM1,HLA-A,NEO1,PDCD10,OXCT1,IRAK1,CTSC,PTEN,GPC3,BAX,PLEKHF1,SLC44A2,MAPK11,ERBB3,CITED2,MAP3K7,GFI1,CNPY3,ITM2C,SPRY2,TRIM62,MSH6,RASGRF1,PLSCR1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,FOS,TXK,GPLD1,CNTNAP1,LDLRAP1,FGFR2,ACVRL1,NR4A3,RYK,GRIN2D,GPER1,HMGA1,LRRK1,FZD5,CD81,SHOX2,FOXA1,UNC93B1,EPHA4,ARFGEF1,LMCD1,NENF,ITPR2,HDAC6,CACNB4,PDGFB,ERP29,SPTB,PCNA,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,TSPAN6,SIVA1,PSMC2,AKR1B1,TNFRSF18,SLC39A10,SCARA3,S100A13,RASGRP1,SMAGP,CYP1B1,SOD1,CD55,CXXC5,TRIM8,ASXL1,ITCH,RNF165,CR2,KLK6,PRKRA,CDK1,RHEB,KDM4D,GPRC5B,AGPAT2,HPSE,MADD,PRKCDBP,ADIPOR1,PSMC1,PPP2R5D,RRAGD,PRKAA2,LASP1,BMF,RASA2,PSMD7,CALM3,SORBS3,NCKAP1,TEC,DUSP5,IL18R1,ANO1,BMP2,VASP,IGF1R,KCNN4,PAK2,MDFIC,NPTN,C10orf54,WNT3A,ZRANB1,PSMA5,MDFI,PDE5A,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PVRL2,PLPP3,CSF1,NFKBIA,NLRC5,JAK3,TOB1,RNF146,DRD1,SORBS1,AVPI1,FOXM1,IL15,PSME2,TP53,ERBB2,P2RX7,IL27RA,RASGRP3,EMP2,BCAP31,PDGFA,ARTN,SRPX,PLCG2,SMO,CDH3,DIXDC1,NFKB2,F2R,DVL2,FRS3,CTH,SULF2,MAP3K3,PPIF,SIRT1,TIMP2,BAG4,AKT1,S100A4,PTGER4,DUSP4,CD40,MAP3K6,PTGS2,PTPRJ,STAT6,PSMD3,SECTM1,CANT1,IRF7,SPTBN5,ARHGAP4,PINK1,CD63,ADGRG1,TAB3,TSPAN15,CTSB,PSMD10,SELL,TGFBR1,GDF15,JAG2,PPP2R3A,ADORA1,BMP7,ZDHHC13,IL17RA,BUB1,IQGAP3,SYK,CAMK2G,P2RX4,HES1,ADAM17,RHOA,PSMB4,WNT10B,ASPM,PLAUR,RC3H2,LITAF,RGCC,BCAR1,MAPK8IP1,BCL10,CTSL,HLA-B,CD8A,BANK1,SWAP70,SCG2,TWSG1,FGF18,UBE2D2,E2F1,ARRB1,PKD2,NDFIP1,L1CAM |
| 1.116e-10 | -22.92 | negative regulation of response to stimulus | biological process | GO:0048585 | 1309 | 278 | 16441 | 2455 |
TXN,ACVR1,LGR4,DNAJC3,TAP1,GATA3,PSME1,KIF26A,GRM5,TP73,PSMD1,RGS12,TGFBR3,RGS3,DNM2,CRY2,SEMA3G,PPP1CA,TNIP1,PBK,SLC35C1,F12,SLC25A5,ABR,ENPP1,ANKRD6,TRAF3IP1,NKD1,NOD2,HDAC1,SPRY4,UNC5B,HSPB1,F2RL1,LZTS1,SEMA6B,NUAK1,ITGA6,HLA-E,SOX9,PRKAA1,ZNRF3,LMNA,MECOM,CALR,ITGA3,PIK3AP1,VASN,DAPK1,PRKG1,SORL1,MAPK7,GPR161,SOCS5,QSOX1,MICB,AMER1,SHARPIN,CALCRL,NPHP3,PSMA4,PLIN5,RASA1,HTT,SEMA4D,ITPR1,PIAS2,NR4A2,XDH,SPRED1,NLRX1,LFNG,INPP5D,DDIT4L,RGS20,BCL2L1,PRKACA,APC2,ZFYVE9,EPM2A,CCND1,CD46,NOV,DACT1,TAX1BP3,DAB2IP,IFIT1,LGMN,CDKN2D,TMBIM1,RNF169,SEMA3B,PRKCQ,CBL,FYN,WFS1,WWTR1,STAT1,TRABD2A,PPP1CB,NRG1,RGS14,CTHRC1,NKX3-1,PLD2,ETS1,GSTP1,ICAM1,HLA-A,CTNNBIP1,PTEN,GPC3,BAX,TMBIM6,ERBB3,MAP3K7,SPRY2,TGIF1,CASK,GRIN1,PIM3,RGS9,TBX18,NR4A3,ITGAV,GPER1,SIGIRR,TNK1,LTBP1,EPHA4,NDRG2,NENF,PDGFB,SH3KBP1,CTNNB1,TSPAN6,IL6ST,PSMC2,DLG1,DUSP10,RGS5,CTTN,PTPRE,CD55,ASXL1,ITCH,EZR,TNFAIP8L1,OPTN,CXXC4,MADD,PRKCDBP,CTNND1,PSMC1,PRKAA2,BMF,ARAP3,RUNX2,LGALS3,SERPINE2,RASA2,UBASH3B,PSMD7,PHLPP1,DHRS3,FBLN1,DUSP5,CORO1B,BMP2,RB1,SPP1,IGF1R,GATA2,FNIP1,C10orf54,WNT3A,PSMA5,MDFI,CYP26B1,STRADB,RANBP9,G2E3,EGFR,ONECUT1,TSC1,NFKBIA,SH3BP4,NLRC5,YOD1,EGFL7,JAK3,SEMA3A,IFI6,TOB1,DRD1,NF2,FOXM1,PSME2,TP53,SOD2,P2RX7,IL27RA,CYP26A1,IER3,PDGFA,BCL6,TWIST1,DVL2,CTH,CHP1,SULF2,PPIF,SIRT1,ERLEC1,TIMP2,AKT1,KREMEN2,FIGNL1,PTGER4,ERBB2IP,DUSP4,DAG1,C3orf33,SOCS3,ARHGAP35,PTPRJ,STK38,STAT6,PSMD3,TLE1,CHMP4B,ZC3HC1,GCLM,PINK1,ARHGEF7,SERPINB9,LRP4,PSMD10,AES,TGFBR1,NOTUM,FZD6,PPP2R3A,HMGXB4,CD109,SNX13,CARD8,ADRBK1,ADORA1,BMP7,UBE2J1,KANK2,FAIM,DUSP1,RHOA,ADAM17,PSMB4,PLAUR,GCLC,PPARA,LITAF,PRICKLE1,STMN3,CARD19,PELI3,BBS2,MAPK8IP1,ARHGAP24,CNOT2,LEMD2,HLA-B,BANK1,SCG2,TWSG1,NMI,ARRB1,NDFIP1,HIPK3 |
| 1.136e-10 | -22.90 | LIU_PROSTATE_CANCER_DN | MSigDB lists | LIU_PROSTATE_CANCER_DN | 456 | 118 | 17758 | 2588 |
MYL9,LTBP1,ACACB,SORBS1,FAM92A1,HSPG2,EPAS1,TSC22D3,FHDC1,FBXO2,GATA3,MRAS,OSR2,SDC1,PHLDA1,CHST2,BTG3,ZNF75D,ST5,TGFBR3,SRPX,GRHL1,METTL7A,DOK4,CAPG,AKR1B1,DAB2IP,NTN4,ACOX2,TUBA4A,TMEM200B,SGCE,TIMP2,CELSR2,SPATA18,SH3BGRL,S100A4,CYS1,TNS1,FZD7,OPTN,DPYSL3,PGF,TNS4,DUOX1,FYN,HLF,WFS1,CORO1C,TSPAN18,MYLK,RCAN2,KLF11,PRIMA1,UNC5B,HSPB1,TRAF5,NR3C2,MRC2,ENO2,PPP1R12A,TBC1D1,SLC16A14,HLA-E,CTSB,FRMD6,GNAL,TGFBR1,ISYNA1,CRABP2,DSE,GSTP1,ARHGEF40,ANO1,SSX2IP,RAVER2,MECOM,CALD1,FLRT3,COL6A1,TPST1,ACTA2,KANK2,NCAM1,C12orf75,ALDH3A2,S100A6,GPR161,SNX7,PDGFC,DDB2,ALDH2,FBLN5,MFI2,LONRF3,PRSS23,TACC1,PIK3R1,COL7A1,NEURL1B,CRISPLD2,MAP1B,CACHD1,SLC6A6,TIMP3,PLEKHH2,ETS2,FGFR2,COL13A1,MFSD2A,FAM83D,SERPINB5,CLIP4,PKD2,FHL1,PER3,COL16A1,CSRP2 |
| 1.141e-10 | -22.89 | PH_domain | interpro domains | IPR001849 | 278 | 82 | 18293 | 2672 |
PLEKHG3,FAM129B,TEX2,PHLDA1,SPTB,ARHGEF16,ACAP2,ARHGAP42,ELMO2,DOK4,OSBPL3,PLCG2,DNM2,DAB2IP,RTKN2,OSBPL7,TIAM1,AKT1,SNTB2,PLEKHO1,ANLN,ADRBK2,ARHGEF26,ABR,PLEKHB1,IRS2,PLCG1,PLCH1,PLEKHG6,ARHGEF19,MPRIP,TRIOBP,PLEKHG1,SPTBN5,GAB1,FGD1,ARAP3,FARP1,ARHGEF3,ARHGEF11,PLEKHJ1,ARHGEF7,CIT,RASA2,PLD2,TEC,SBF1,PHLPP1,DOCK11,ARHGEF40,SNTA1,ADRBK1,RALGPS2,MCF2L,EXOC8,PLEKHF1,CADPS2,FARP2,RASGRF1,PLEKHA6,ARAP2,ARHGEF28,PHLDB3,SPATA13,PLEKHA7,SNTB1,FAM109A,RASA1,ARHGAP24,DGKH,SWAP70,PLEKHH2,APPL2,ARAP1,FGD6,PLD1,AFAP1,ARHGEF9,DEF6,NGEF,DOCK9,ARHGEF4 |
| 1.146e-10 | -22.89 | PATIL_LIVER_CANCER | MSigDB lists | PATIL_LIVER_CANCER | 698 | 164 | 17758 | 2588 |
AGRN,TRIM24,ARFGEF1,UBE2Q1,CDKN2C,PCNA,HSF2,UBE2T,IMPAD1,CAPG,TUBG1,RGS5,ACOX2,SLC39A10,PXMP4,STK35,TUBA4A,LAMP2,PLK1,PBK,ACBD3,TMEM98,KDELR3,LOXL2,PTGFRN,TP53I3,CDK1,TYSND1,PRIM1,LRRC42,PLCG1,MID1IP1,RAB11FIP1,EIF4EBP2,KPNA2,GLA,LSM14B,RTN3,E2F8,GAB1,CAPN1,RRAGD,GRN,PARP12,HJURP,KIF23,GPSM2,TTYH3,MYO5C,CALR,SPP1,ZCCHC17,TIMP1,NEK2,USP1,KNTC1,RFX5,MPHOSPH9,TMED2,CCDC88A,PIGC,FADS2,LPGAT1,SHARPIN,MYBL2,KIF20B,PTPRF,ONECUT1,NCOA3,H1F0,DCK,CDCA5,DONSON,CTSA,EFNA1,MAL2,TOB1,RUSC1,RAD21,NQO1,DLGAP5,NF2,NDRG1,PTTG1,HDAC11,NUF2,BCAP31,KIAA1147,SYTL2,RAD23A,CD46,ACAP2,CCNA2,PLK4,VAT1,NOTCH3,LRP11,ETV4,DVL2,CPD,ERMP1,OSTM1,CDC20,CLSTN1,HTATIP2,NUSAP1,PKMYT1,MYPOP,PPP2R5A,PAFAH1B3,DDOST,PEX2,ZNF704,XRCC3,B4GALT3,C1orf43,ARNT,GCLM,MZT1,MPZL1,DCAF7,CDCA8,PSMD10,GMCL1,INTS8,LBR,BEX2,XPR1,SAC3D1,CD109,TOP2A,CEP97,GNB5,IRAK1,CENPJ,GPC3,MGAT4A,FAM63A,CKS1B,ADAM15,BUB1,NCOA2,CRTAP,CAMK2G,SMC4,P2RX4,HMMR,SYPL1,ZWINT,MBNL3,CCDC34,COL7A1,KIF11,NDRG3,MAP1B,CDKN2AIPNL,DGCR2,E2F1,HMGA1,PLOD3,NUP37,NCAPG2,UBE2C,ESPL1 |
| 1.202e-10 | -22.84 | regulation of protein modification process | biological process | GO:0031399 | 1701 | 346 | 16441 | 2455 |
TXN,PPP4R4,ACVR1,IBTK,GRIK2,TRIM5,DNAJC3,XIAP,FBXO2,CUL1,NRG2,GATA3,PSME1,IL18,CCNB1,SEPT4,SNX9,CARD10,PHF1,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,CTGF,RGS3,IL31RA,PIK3CA,CRY2,NEK4,TNIP1,PBK,SPRTN,PRKAR2B,PIAS3,ENPP1,PLCG1,CAMK2N2,ANKRD6,LIMK1,TBX1,TRAF3IP1,PPP2R4,NOD2,MAP3K11,SPRY4,HSPB1,F2RL1,GAB1,CDKN1C,NUAK1,SOX9,PRKAA1,SH3RF2,MECOM,TFAP4,RAC2,CYR61,FBXO7,MAP3K9,SORL1,MYDGF,NCAM1,PPP6R1,SOCS5,MMD,MAPKAPK3,CALM1,EPHA1,ILK,KDM3A,PSMA4,RASA1,FAS,FNTA,PRKAG2,HTT,SEMA4D,PELI2,FAM83D,STK39,EFNA1,GDF11,MAP3K5,XDH,SPRED1,IQGAP1,PRKACA,FLT3,CCND1,APLP2,ST5,CCNA2,RALB,DACT1,CDKN1B,DAB2IP,PDE4D,DLG3,RASGEF1A,CDKN2D,CAMSAP3,PSRC1,RIPK2,FZD4,DMTN,CDCA2,PKMYT1,FZD7,IRS2,FYN,JAK1,CCNB3,PPP2R5A,STK26,CORO1C,WFS1,WWTR1,KIAA1804,SLC27A1,NRG1,RGS14,ARNT,PRKAR1A,FARP1,HSP90B1,TAOK2,NKX3-1,TRAF2,SDC4,FLOT1,HERC5,PKN1,GSTP1,TIPRL,FGF19,ICAM1,SNTA1,DIRAS3,PDCD10,IRAK1,PTEN,KNDC1,BAX,MAPK11,ERBB3,MAP3K7,GFI1,SPRY2,CRTAP,RASGRF1,PDGFC,RAPGEF2,GRIN1,YES1,GPLD1,CDK5RAP1,FGFR2,ACVRL1,RYK,GRIN2D,GPER1,CENPE,LRRK1,FZD5,CD81,JARID2,CCNC,CASP3,CAMKK1,EPHA4,ARFGEF1,NDRG2,NENF,PDGFB,ERP29,SPTB,FANCI,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,DLG1,DUSP10,TNFRSF18,SLC39A10,RASGRP1,PLK1,SOD1,ITCH,EZR,CDK1,VCP,KDM4D,GPRC5B,MADD,PRKCDBP,CAB39,PSMC1,PPP2R5D,LMTK3,PPP1R2,PPP1R12A,RASA2,UBASH3B,DNAJB2,PSMD7,CALM3,SORBS3,TEC,PHLPP1,FBLN1,DUSP5,BMP2,RB1,IGF1R,GATA2,PAK2,FNIP1,BRAT1,MDFIC,NPTN,PIM1,WNT3A,PSMA5,CCDC88A,MDFI,HMG20B,STRADB,PDE5A,EIF2AK1,RANBP9,EGFR,CDK5R1,FECH,BCAR3,MAPKAPK2,TSC1,INSR,PLPP3,CSF1,DCUN1D1,JAK3,CTBP1,PROM2,DRD1,CCNE2,AVPI1,NF2,IL15,FOXM1,PSME2,CTDSPL,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,EMP2,STIL,SYTL2,PER2,PDGFA,SVBP,PPME1,KIF14,BCL6,TWIST1,APIP,F2R,CTDSP2,HSPA2,DVL2,FRS3,CKS2,CHP1,MAP3K3,SIRT1,TIMP2,BAG4,AKT1,CDC20,DUSP4,CD40,CDC25C,MAP3K6,DAG1,C3orf33,SOCS3,DNAJC10,PTPRJ,STK38,PSMD3,SPTBN5,EFNA5,PPP2R2D,CNEP1R1,CTDSP1,ARFGEF3,PINK1,TAB3,LRP4,PSMD10,TGFBR1,GDF15,TRIB2,PPP2R3A,SH2D4A,CD109,ADORA1,BMP7,CKS1B,BRD7,TRIM21,H2AFY,BUB1,HEXIM2,IQGAP3,SYK,CAMK2G,DUSP1,HES1,ADAM17,PSMB4,PLAUR,GCLC,RGCC,PRICKLE1,MAPK8IP1,BCL10,LEMD2,BANK1,SWAP70,RAP2C,FGF18,NMI,TADA2B,ARRB1,PPP2R3C,PKD2,NDFIP1,UBE2C,HIPK3,PKIA |
| 1.247e-10 | -22.80 | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP | 192 | 63 | 17758 | 2588 |
LAMP1,KLF2,ARAP3,LGALS3,CD63,CTSB,CAST,HLA-F,HAL,SOD2,ASAH1,FAM198B,CDIPT,PRRG4,HLA-A,ICAM1,IER3,ARHGEF10L,GNS,CD46,APLP2,FRY,KIF13B,DRAM1,SORL1,CTSD,TMBIM1,CKAP4,DUSP1,CYP1B1,SYPL1,RHOA,MPP1,SAT1,BNIP3L,UTRN,VAMP3,CDA,PYGL,NPC2,BLVRA,LHFPL2,CRISPLD2,FUCA1,HLA-B,NAAA,MID1IP1,SERPINA1,WIPI1,SIPA1L1,NFKBIA,CLIP4,DYSF,ZDHHC7,CANT1,CLMN,CTSA,PLXND1,PDXK,LTA4H,RTN3,KLF7,RRAGD |
| 1.249e-10 | -22.80 | PROTEIN_KINASE_DOM | prosite domains | PS50011 | 481 | 126 | 11866 | 1802 |
TNK1,ACVR1,CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,MAPK4,CAMK1D,GRK6,FLT3,DDR1,PRKACA,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CDKL5,PASK,PLK4,EPHB4,SCYL3,STK35,MAP3K3,PLK1,NEK4,MARK1,AKT1,RIPK2,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,MAP3K6,STK17B,ADRBK2,CDK1,ULK2,EPHA10,FYN,JAK1,STK26,CDK19,PLK2,PTK7,STK38,LIMK1,AXL,MYLK,KIAA1804,MAP3K11,MAPK13,MLKL,RNASEL,MAPK12,PRKAA2,CDK17,TAOK2,LMTK3,DYRK3,PINK1,NUAK1,CIT,PRKAA1,TGFBR1,TEC,TRIB2,PKN1,MERTK,BMP2K,ADRBK1,IRAK1,IGF1R,CDK16,PAK2,PRKCI,SGK3,DAPK1,PRKG1,NEK2,MAP3K9,SGK1,MAPK11,BUB1,ERBB3,PIM1,MAP3K7,MAPK7,MAST4,PHKG2,SYK,CAMK2G,CASK,MAPKAPK3,TESK1,STRADB,EIF2AK1,YES1,EPHA1,PIM3,ILK,PDIK1L,EGFR,STK17A,TXK,MAPKAPK2,INSR,FGFR2,ACVRL1,CSNK1G1,RYK,AURKA,CDK18,STK39,LRRK1,MAP3K5,JAK3,NRBP1,HIPK3,MELK,RPS6KA3,DMPK |
| 1.300e-10 | -22.76 | MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | MSigDB lists | MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | 166 | 57 | 17758 | 2588 |
LASP1,PCOLCE,HSPG2,EPAS1,ST14,SOX9,CYB561,IL13RA1,TGFBR1,ETS1,CA8,ANO1,SIRPA,FZD6,RAD23A,IER3,APLP2,WEE1,CYR61,CALD1,VASN,CAPG,DNM2,ACTA2,F2R,S100A6,TUBA4A,CPD,HES1,TGIF1,PDGFC,TIMP2,AKT1,FZD4,GUSB,SNTB2,SAT1,UTRN,TNS1,COL7A1,NFIB,DPYSL3,GALNT3,PIAS3,ATP1A1,ETS2,PLOD2,BMP1,SERPINB5,FHL1,ITGAV,COL16A1,FOXA1,RPS6KA3,DLAT,EGLN1,EHD1 |
| 1.301e-10 | -22.76 | cell surface receptor signaling pathway | biological process | GO:0007166 | 2257 | 440 | 16441 | 2455 |
ACVR1,LGR4,IL15RA,GRIK2,TRIM5,RET,XIAP,GATA3,CUL1,NRG2,IL18,PDGFRL,PSME1,PLXNA1,GRM5,CALM2,ZYX,PSMD1,TGFBR3,CTGF,ELMO2,IL31RA,PIK3CA,IRF2,TACSTD2,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,IL10RB,TIPARP,ACVR1C,CASP9,CDA,PRKAR2B,AGO4,ZFAND5,ARF4,ABR,SGPP1,PGF,PLCG1,AREG,LIMK1,NKD1,HDAC1,MAPK13,EIF4EBP2,RNASEL,UNC5B,HSPB1,GAB1,FGD1,SEMA6B,THEMIS2,HLA-E,ITGA6,SOX9,PRKAA1,NOTCH2,ZNRF3,MERTK,TNFRSF19,TSPAN7,MESDC2,ITGA3,MEGF8,FLRT3,DAPK1,TNFRSF12A,CD70,MAPK7,NCAM1,NUP85,SOCS5,MAPKAPK3,STAT4,MICB,CALM1,AMER1,ANO6,SHARPIN,CALCRL,EPHA1,NPHP3,CYFIP2,ELK1,ILK,PSMA4,RASA1,FAS,PTPRF,IL1R1,FNTA,PRKAG2,SEMA4D,PELI2,CSNK1G1,ITPR1,OSMR,CABIN1,EFNA1,GDF11,ARPC2,NUP58,RPS6KA3,IRF1,SPRED1,REPS2,TCTN2,LFNG,CD82,INPP5D,RPS6KA1,IQGAP1,IL13RA1,BCL2L1,GRK6,CD274,PRKACA,DDR1,APC2,FLT3,ZFYVE9,CCND1,SP100,RALB,DACT1,DOK4,CDKN1B,TAX1BP3,DAB2IP,PDE4D,IFIT1,EPHB4,TSPAN1,RASGEF1A,SEMA3B,MX1,RIPK2,FZD4,PRKCQ,PYGO1,CBL,ITPR3,FZD7,GIGYF1,EPHA10,IRS2,FYN,JAK1,NGFRAP1,SLC9A6,AXL,SIPA1L1,TSPAN18,WWTR1,STAT1,PPP1CB,TRABD2A,SLC27A1,NRG1,RGS14,PRKAR1A,MAPK12,CTHRC1,ARHGEF3,TNRC6C,MPZL1,TRAF2,EPS8,CCM2,HERC5,BTN3A1,PLD2,IFT27,EFNB1,FGF19,ICAM1,ADGRB2,HLA-A,SGPL1,CTNNBIP1,IRAK1,ITGB8,PTEN,MCF2L,FUT8,CD9,BAX,ADAM15,MAPK11,ERBB3,MAP3K7,CITED2,SPRY2,TRIM62,FARP2,AMOTL2,RASGRF1,TGIF1,PDGFC,ARHGEF28,BCL9,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,NEURL1B,FOS,GPLD1,TXK,KIAA0141,ACVRL1,FGFR2,RYK,NR4A3,GRIN2D,SSNA1,ITGAV,NUP37,FZD5,CD81,FOXA1,RGMA,CCNC,MYL9,TNK1,CASP3,LTBP1,EPHA4,NDRG2,F11R,ITPR2,CACNB4,PDGFB,SDC1,DNER,SPTB,KREMEN1,TRIM68,SH3KBP1,ZFYVE16,NUP210,RPS6KA2,CTNNB1,SHC3,ZCCHC12,IL6ST,TSPAN6,SIVA1,PSMC2,MITF,TNFRSF18,MYH14,PTPRE,IL1RAP,RASGRP1,MARK1,TRIM8,CELSR2,ITCH,USP18,CR2,ROR1,RHEB,CXXC4,MDK,MADD,CAB39,CTNND1,KPNA2,ADIPOR1,PPP2R5D,MYL12B,PSMC1,RRAGD,PCSK5,PRKAA2,RUNX2,LRRFIP2,HLA-F,RASA2,PSMD7,ATP6V1E2,CALM3,TEC,NCKAP1,PHLPP1,FBLN1,DUSP5,IL18R1,BMP2,VASP,IGF1R,PAK2,PRKCI,NPTN,HLA-C,C10orf54,ZRANB1,WNT3A,PSMA5,RGMB,STRADB,TCF7,IFIT3,EGFR,CDK5R1,MAPKAPK2,ONECUT1,TSC1,INSR,PLPP3,CSF1,ITGA7,PHLPP2,NFKBIA,LTBP2,JAK3,SEMA3A,IFI6,TOB1,RARG,COL16A1,RNF146,SORBS1,PSME2,SLC2A8,TP53,P2RX7,ERBB2,IL27RA,RASGRP3,STIL,ARHGEF16,CDK14,TTC21B,PDGFA,SS18,ATP6V0B,PLCG2,SMO,CDH3,GOT1,DIXDC1,NOTCH3,OAS3,NFKB2,DVL2,FRS3,SULF2,BAG4,KREMEN2,AKT1,PTPRU,ERBB2IP,CD40,DUSP4,MYL12A,SOCS3,DUOX1,PTPRJ,IDE,RBL1,PTK7,PSMD3,STAT6,TLE1,RCAN2,EFNA5,SPTBN5,IRF7,PLXND1,ARHGAP4,ABCA1,LIFR,SORT1,CPEB4,ARHGEF11,ADGRG1,TAB3,ARHGEF7,LRP4,PSMD10,TGFBR1,GDF15,AES,NOTUM,JAG2,ITGA2B,IL22RA1,FZD6,PPP2R3A,NRP2,HMGXB4,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,TRIM21,BRD7,IL17RA,TSPAN13,SYK,CAMK2G,P2RX4,HES1,ADAM17,RHOA,WNT10B,PSMB4,IFITM3,NR4A1,PLAUR,MAML2,AKAP3,PELI3,BBS2,BCAR1,LEPR,BCL10,HLA-B,CD8A,TWSG1,FGF18,UBE2D2,DTX4,E2F1,ARRB1,GEM,ATP6V1C1,ARHGEF9,L1CAM,ZBTB33,ARHGEF4,NGEF |
| 1.303e-10 | -22.76 | LTE2_UP.V1_UP | MSigDB lists | LTE2_UP.V1_UP | 179 | 60 | 17758 | 2588 |
GCLM,EPAS1,GALNT12,ABCG2,NUCB2,PJA2,FAM46C,UHRF1BP1L,TNS3,ADORA1,DPYSL2,BMP7,MGAT4A,KIF13B,LMO4,ELF5,REEP1,OPN3,AOX1,DRAM1,SORL1,ECI2,ACOX2,SCARA3,SLC12A2,ULBP2,MYO5A,EPHX1,CYP1B1,GCNT1,P2RX4,SOAT1,SEC23A,PGM1,MBP,PBK,STAU2,PTGER4,BNIP3L,DIAPH2,GGH,NPC2,DUSP4,CYFIP2,SPTLC2,SGPP1,EPN3,IL1R1,BTG1,SERPINA1,FA2H,P4HA2,SLC9A6,CSGALNACT1,APPL2,FAM117A,MAOA,CLMN,MAP3K5,RRAGD |
| 1.303e-10 | -22.76 | WU_CELL_MIGRATION | MSigDB lists | WU_CELL_MIGRATION | 179 | 60 | 17758 | 2588 |
LGALS3,IGFBP6,EPAS1,ST14,FXYD3,ESRP1,SOX9,EPS8,ARL4C,RGS20,GATA3,ASAH1,COL18A1,DSE,S100A2,FBLN1,SIRPA,EPCAM,RAC2,SCNN1A,CDH1,RNF128,CYR61,AIM1,CAPG,DAPK1,CLDN4,CDH3,TACSTD2,LIMCH1,TSPAN13,S100A6,ERAP2,TUBA4A,PDGFC,CD55,COL6A2,S100A4,CDA,PTGER4,EMP3,ARHGDIB,LOXL2,MEST,MAP1B,GALNT3,PTGS2,FYN,TIMP3,KCNK1,AXL,WWTR1,RAB31,DTX4,SERPINB5,MAOA,KLF5,MAPK13,F2RL1,PTGES |
| 1.523e-10 | -22.61 | regulation of protein serine/threonine kinase activity | biological process | GO:0071900 | 433 | 115 | 16441 | 2455 |
CCNE2,CCNC,CASP3,SPRED1,AVPI1,IQGAP1,EPHA4,P2RX7,ERBB2,CCNL1,PDGFB,FLT3,STIL,ERP29,CARD10,GRM5,TP73,CALM2,CCND1,PDGFA,CDKN2C,CCNA2,RALB,RGS3,DUSP10,CDKN1B,DAB2IP,CDKN2D,HSPA2,RASGRP1,DVL2,CKS2,PLK1,SIRT1,SOD1,PSRC1,RIPK2,AKT1,FZD4,PRKAR2B,PKMYT1,CD40,DUSP4,CDC25C,CDK1,MAP3K6,PTPRJ,CCNB3,STK38,MADD,KIAA1804,NOD2,MAP3K11,CAB39,SLC27A1,RGS14,HSPB1,GAB1,PRKAR1A,CDKN1C,TAB3,TRAF2,PRKAA1,CALM3,PSMD10,HERC5,PKN1,TRIB2,GSTP1,DUSP5,BMP2,DIRAS3,TFAP4,PDCD10,IRAK1,PTEN,BMP7,FBXO7,MAP3K9,CKS1B,H2AFY,SORL1,MAPK11,MDFIC,PIM1,HEXIM2,IQGAP3,MAP3K7,SYK,SPRY2,MDFI,DUSP1,ADAM17,MAPKAPK3,RAPGEF2,CALM1,RGCC,PDE5A,ILK,EGFR,CDK5R1,MAPKAPK2,CDK5RAP1,INSR,PRKAG2,FGF18,ARRB1,PKD2,EFNA1,FZD5,MAP3K5,CD81,UBE2C,HIPK3,PKIA |
| 1.530e-10 | -22.60 | Golgi apparatus part | cellular component | GO:0044431 | 870 | 196 | 17570 | 2579 |
UNC93B1,SLC35D2,AGRN,HSPG2,IL15RA,ARFGEF1,TRAPPC8,TGOLN2,MGAT5B,CDIPT,PJA2,SNX9,PDGFB,SDC1,RIC1,CHST2,SLC9A7,NCS1,CHPF,INPP5E,AP1M2,ENTPD4,MUC4,CABP1,ARL1,LMAN2L,STEAP2,FUT1,DNM2,TFG,SCARA3,PACSIN1,MGAT5,RASGRP1,ATL1,LAP3,ACBD3,SLC35C1,ARFRP1,KIF13A,GALNT7,MCFD2,RAB2B,RHEB,OPTN,MAN2A2,HS6ST1,WIPI1,AREG,GNPTAB,ATP7B,CHPT1,RAP1GAP,NRGN,RTN3,PCSK5,PIFO,LMTK3,SCOC,HLA-E,HLA-F,RAB6A,NOTCH2,B4GALT4,QSOX2,B4GALNT1,DOPEY2,B3GALNT1,OCRL,NECAB3,SLC30A6,TPST1,PRKCI,SORL1,HLA-C,PIKFYVE,NCAM1,WNT3A,MPHOSPH9,PPP6R1,TMED2,KDELR1,CHSY3,NAGPA,GCC2,B3GNT7,QSOX1,MGAT4B,GYLTL1B,FBXO8,GOLT1A,C3orf58,ZDHHC3,EGFR,GLCE,GNAS,RAB31,ARAP1,ZDHHC7,B4GAT1,PLD1,SLC2A4,LFNG,GALNT12,XYLT1,ATP2C2,APOO,RGS20,FAM198B,EMP2,APC2,EXT2,BCAP31,SDF4,PDGFA,MUC16,CDH1,XYLT2,NOTCH3,LMAN1,RAB27B,EBAG9,CHP1,SULF2,CPD,SEC23A,CLCN3,COG2,CLSTN1,SLC11A2,PXYLP1,RAB38,PKMYT1,B3GALNT2,TAPBP,STX10,STK26,CANT1,RAB29,HS3ST3B1,B4GALT3,ST3GAL1,NDST3,COPG1,ARFGEF3,GOLIM4,SORT1,TRAPPC10,MAN1A2,BACE1,ATP9A,SDC4,CTSZ,DSE,POMGNT1,PARM1,HLA-A,ZDHHC21,PDCD10,FUT2,CTSC,MGAT1,A4GALT,MGAT4A,GPC3,FAM20B,FUT8,SLC35B4,ZDHHC13,SLC35A1,GCNT1,B3GALT6,MOB4,PDGFC,B3GNT2,SYBU,FURIN,C1GALT1C1,COL7A1,FAM109A,FNDC3A,GALNT3,HLA-B,NUCB1,LDLRAP1,SERPINA1,RND3,SLC35B3,CSGALNACT1,ARFGAP3,ARRB1,GPER1,FZD5,NDFIP1,ABCG1,GOLGB1 |
| 1.689e-10 | -22.50 | cell leading edge | cellular component | GO:0031252 | 346 | 96 | 17570 | 2579 |
MTM1,NF2,SSH1,S100A11,IQGAP1,HDAC6,SNX9,APC2,EPS8L2,INPP5E,CDH1,CTNNB1,CDKL5,PIK3CA,DNM2,TUBG1,CTTN,TLN2,PACSIN1,FLOT2,SCYL3,SGCE,SYNE2,EZR,DAG1,ARF4,LCP1,ARHGEF26,GABARAPL1,DPYSL3,PLCG1,PTPRJ,CORO1C,MYLK,NRG1,PLXND1,PIEZO1,SPRY4,ARF6,COBL,FGD1,DDX58,WASF3,INPPL1,ARAP3,PACSIN2,ARHGEF7,CIT,EPS8,FLOT1,GABRG2,NCKAP1,CNTNAP2,SSX2IP,CORO1B,RAC2,VASP,ANK1,ADORA1,RINL,MCF2L,PRKCI,ACTA2,TNFRSF12A,SPRY2,S100A6,MYO5A,CCDC88A,EPB41L5,ADAM17,RHOA,GRIN1,SPATA13,SCRIB,RAB3IP,AIF1L,ILK,BCAR1,ANTXR1,RASA1,STX3,FRMD4B,RASGRP2,GNAS,KLHL2,TSC1,PLEKHH2,SWAP70,FGD6,DYSF,PKD2,ITGAV,GPER1,ARPC2,NRBP1,ARHGEF4 |
| 1.750e-10 | -22.47 | transferase activity, transferring phosphorus-containing groups | molecular function | GO:0016772 | 916 | 206 | 16491 | 2452 |
LTBP1,NMRK1,TNK1,ACVR1,TRIM24,AK7,CAMKK1,RET,EPHA4,PDGFRL,NANS,CAMK1D,CDIPT,CCNB1,DAPK2,PAK6,WEE1,TGFBR3,RPS6KA2,CDKL5,PASK,PAPSS1,DLG1,PIK3CA,POLL,PIK3CD,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,AURKB,ROR1,STK17B,CDK1,ADRBK2,ULK2,PRIM1,PI4K2B,FASTKD1,GNPTAB,LIMK1,PLK2,MYLK,MAP3K11,MAPK13,PIK3C2B,RNASEL,ITPKA,CHPT1,PRKAA2,CDK17,LMTK3,NUAK1,PRKAA1,DGKQ,SOX9,ADCK5,TEC,MERTK,BMP2K,IGF1R,FAM20C,PFKL,PAK2,DAPK1,MAP3K9,ADCK2,PRKG1,PRKCI,NEK2,NPTN,ALPK1,PIM1,PIKFYVE,MAPK7,DGKG,MAST4,PHKG2,MMD,MAPKAPK3,ADCK3,TESK1,PIP4K2C,STRADB,EIF2AK1,EPHA1,PDK3,PKM,ILK,PDIK1L,EGFR,CDK5R1,STK17A,DGKH,MAPKAPK2,NT5C2,INSR,PRKAG2,UAP1,DCK,CSNK1G1,PAPD5,PRPS2,MPP2,ALPK3,AURKA,STK39,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,PAPSS2,UGP2,RPS6KA1,ETNK1,DGKA,TESK2,ERBB2,MAPK4,GRK6,PRKACA,DDR1,FLT3,CDS1,CDK14,CCND1,FICD,PLK4,GYS1,EPHB4,OAS3,PHKA2,DLG3,SCYL3,SEPHS1,MAP3K3,AKT1,RIPK2,RFK,PFKFB2,PANK1,TEP1,PRKCQ,PKMYT1,XRCC6BP1,MAP3K6,EPHA10,FYN,JAK1,CDK19,STK26,PTK7,AXL,STK38,KIAA1804,MLKL,PDXK,MAPK12,GALK1,CMAS,DYRK3,TAOK2,PINK1,CDS2,CIT,GNE,TGFBR1,PKN1,TRIB2,NRP2,IRAK1,ADRBK1,CDK16,FAM20B,SGK3,SGK1,MAPK11,BUB1,ERBB3,AK3,ERCC2,MAP3K7,SYK,CAMK2G,CASK,PAPD7,MPP1,NADK2,AK4,YES1,PIM3,POLD3,DGKE,TXK,ACVRL1,FGFR2,RYK,PGM2L1,LRRK1,CMPK2,HIPK3,MELK |
| 1.817e-10 | -22.43 | KARLSSON_TGFB1_TARGETS_DN | MSigDB lists | KARLSSON_TGFB1_TARGETS_DN | 198 | 64 | 17758 | 2588 |
CCNI,GAA,UPF3B,TRIM24,PSME2,XIAP,NDRG2,FTH1,F11R,CDKN2C,PCNA,SLC44A1,TECR,SLC39A10,CTDSP2,LAMP2,ENPP4,SMARCA2,TNIP1,SH3BGRL,SYNE2,RNF11,TMEM98,BNIP3L,EZR,H2AFV,SESN1,ALCAM,DAG1,GABARAPL1,SHROOM3,WWTR1,MAOA,EFNA5,ARNT,GRN,ZNF395,CTSB,ADO,CTSZ,AES,KCNC4,SSX2IP,CTNNBIP1,ADD3,CST3,FUT8,COL6A1,TMBIM6,HLA-C,EPHX1,MMD,PIK3R1,NPC2,DCTN6,CNTNAP1,PTPRF,H1F0,TWSG1,DBI,TMC5,APPL2,CTSA,NDFIP1 |
| 1.981e-10 | -22.34 | BASAKI_YBX1_TARGETS_UP | MSigDB lists | BASAKI_YBX1_TARGETS_UP | 272 | 80 | 17758 | 2588 |
S100A11,TUBB4B,PTTG1,NDC80,NUF2,KIF2C,CCNB1,FAM101B,EMP2,CENPN,FANCI,CCNA2,CTGF,SIVA1,KIF22,NTN4,RNF26,MYBL1,CTH,TUBA4A,PLK1,KRT80,TIMP2,CENPA,PBK,CDC20,CDA,HTATIP2,AURKB,ANLN,H2AFV,CDK1,RHEB,DPYSL3,AREG,PLK2,ZNF367,AXL,KPNA2,ANXA3,PINK1,HJURP,DEPDC1,FRMD6,CENPI,CCM2,CDCA3,CDCA8,KIF23,S100A2,GSTP1,SAC3D1,E2F7,DAZAP1,IRAK1,CYR61,PRC1,NEK2,TNFRSF12A,BUB1,DDB2,ZWINT,PRSS23,KIF20A,ASPM,WHSC1,BORA,MAP1B,RND3,NFKBIA,SH3BP4,FAM83D,OSMR,AURKA,CCNB2,UBE2C,L1CAM,ESPL1,MELK,RUSC1 |
| 2.026e-10 | -22.32 | GSE3982_MAC_VS_BCELL_UP | MSigDB lists | GSE3982_MAC_VS_BCELL_UP | 194 | 63 | 17758 | 2588 |
CMAS,GNPDA1,VANGL1,ATP9A,CIT,CDCA8,PBX3,TGOLN2,PLXNA1,COX6C,SPSB1,PPP2R3A,COX7A2,SYTL2,TOP2A,CYP1A1,DPYSL2,OCRL,GALNS,PAPSS1,TMEM51,KCNS3,BCL6,DIXDC1,TACSTD2,MTMR11,OAS3,TLN2,EPHX1,GFPT1,MPP1,DENND1B,CDA,ACO1,AK4,IDH1,ADRBK2,STX3,RHEB,SEC14L2,CD83,GABARAPL1,FUCA1,CTNS,FAM64A,TIMM8A,HNRNPH2,P4HA2,NEIL3,WWTR1,PLA2G15,DBI,NR4A3,BMP1,VSIG10,KPNA2,ANXA9,FHL1,PDXK,ZMIZ1,FZD5,ARSB,ACOT7 |
| 2.250e-10 | -22.21 | cytoskeleton | cellular component | GO:0005856 | 1933 | 379 | 17570 | 2579 |
CFAP74,SSH1,ADD1,FAM129B,KLC2,XIAP,CNTROB,SYTL4,CCNB1,SEPT4,PJA2,FAM101B,KIF26A,PHF1,PICK1,CALM2,ZYX,STIM1,DNAH6,CABP1,DNM2,TUBG1,HYLS1,ZBTB18,ODF2L,TUBA4A,SPEF2,SGCE,SMARCA2,KIFC2,SNTB2,DSTN,UXT,PRKAR2B,TNS1,KIF13A,AURKB,CCNF,SLC25A5,MYOM1,LCP1,MPRIP,MID1IP1,CAMK2N2,WDR11,DNM1L,PLK2,TRAF3IP1,MYLK,FAM110C,NOD2,MAP3K11,TMOD2,RELL1,HSPB1,TRAF5,ANXA11,FGD1,DDX58,INPPL1,FRMD4A,NUAK1,DGKQ,KIF23,TXNDC9,LMNA,FLII,RAC2,ZCCHC17,FRY,NEK2,DAPK1,SLAIN2,MYLIP,NUP85,C9orf72,TTLL1,DNAI1,EPB41L5,KIF20A,CEP89,B9D2,CALM1,FHL2,PLS1,KIF20B,ILK,FRMD4B,FNTA,PLEKHH2,HTT,FAAH,WDR19,AGBL5,FAM83D,FGD6,AURKA,MDH1,STK39,DRP2,NDE1,ARPC2,CFAP20,HOOK1,RUSC1,FRMPD3,KIF3C,CEP70,TCTN2,DLGAP5,TMSB15A,TRIP10,TUBB4B,RPS6KA1,ACTR8,IQGAP1,NDRG1,PKP2,BCL2L1,PRKACA,APC2,MNS1,APPBP2,SCNN1A,CDH1,PDE4D,ZNF365,FLOT2,SNX10,MYO5B,CAMSAP3,SSH3,PSRC1,RIPK2,CAPN6,DMTN,SEPT6,SYNE2,CYS1,VPS4B,UTRN,KIF1C,NUSAP1,SP4,GABARAPL1,NIN,CEP162,FYN,PDLIM3,JAK1,SHROOM3,STK26,CORO1C,SIPA1L1,TRIOBP,RAB29,RGS14,GEN1,COBL,TTC8,WASF3,FARP1,MZT1,TAOK2,CKAP2,RASSF7,FLOT1,NES,SPDL1,DNAH3,IFT27,RND1,CKAP5,SNTA1,CAPN2,ANK1,ADD3,RNF128,PHF7,CENPJ,CALD1,TUBGCP6,PRC1,KLC3,ERCC2,SGCB,SPRY2,FARP2,POU6F1,LCA5,CASK,CTNNAL1,FMN1,TACC1,MPP1,PLEKHA7,PARP4,RAB3IP,YES1,SNTB1,AIF1L,SKA1,KIF11,ABLIM2,DCTN6,NUCB1,LDLRAP1,CTNS,CCDC6,SSNA1,GPER1,CENPE,WDR62,ESPL1,MYL9,NDRG2,F11R,KIF2C,HDAC6,MAP1LC3B,SPTB,SH3KBP1,INPP5E,PCNA,RPS6KA2,CTNNB1,CNTRL,DPYSL2,CEP78,DDHD2,ABCA2,CAPG,DLG1,KIF22,RP2,MYH14,CTTN,TLN2,MYRIP,NEB,CCDC38,PLK1,KRT80,PCGF5,MARK1,STAU2,FOPNL,CKAP2L,EZR,KLK6,ARHGDIB,ANLN,CDK1,STK17B,DPYSL3,DZIP1L,TNS4,TRIM9,PLEKHG6,NEIL1,WIPI1,MAP2,EPB41L4A,MYL12B,LASP1,PIFO,USH1C,BMF,ARAP3,PPP1R12A,CALM3,SORBS3,RACGAP1,TEC,SSX2IP,MYO5C,CORO1B,RB1,VASP,RINL,KIF13B,TBCD,PRKCI,KNTC1,LRIF1,MPHOSPH9,CKAP4,C9orf9,TPGS2,CORO2A,KBTBD8,NUBP1,RANBP9,MAPKAPK2,TSC1,H1F0,KIF12,SHROOM2,CCNB2,JAK3,AFAP1,GAS2L1,DYNLRB1,SORBS1,NF2,UPF3B,ZMYND10,MICALL2,STIL,TMSB15B,TTC21B,LRRC45,SS18,TACC2,KIF14,PLK4,ESPN,EPB41L4B,NOTCH3,CHP1,TAF5,AKT1,CDC20,CCSAP,MYL12A,DAG1,ARHGAP35,BFSP1,SPTBN5,SGOL1,MAD2L1BP,REEP4,BIN1,FBLIM1,PINK1,PACSIN2,FRMD6,POC1B,CIT,ERCC6L,CDCA8,PSMD10,TRIB2,SAC3D1,KIF5B,CCDC92,TOP2A,MZT2A,TBC1D31,CEP97,CDK16,LLGL2,GTF2F2,TFAP2A,ACTA2,CLIP2,RPGR,MYO5A,PGM1,ADAM17,RHOA,CFAP46,ASPM,SYBU,RGCC,BBS2,BCAR1,SPAG1,MAP1B,BCL10,KLHL2,ARHGAP24,UACA,PPP2R3C,PKD2,GEM,CEP41,SNPH,DIS3L |
| 2.359e-10 | -22.17 | localization | biological process | GO:0051179 | 4664 | 827 | 16441 | 2455 |
DOC2A,ACACB,ADD1,IBTK,GRIK2,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,CACNA2D2,TRAPPC8,TGOLN2,LGI3,BAIAP3,SYTL4,SNX9,SLC35E4,TP73,CALM2,NAPG,PQLC2,AP1M2,TGFBR3,DNAH6,SLC46A1,ATP13A3,DNM2,SEMA3G,PIK3CD,TINAGL1,TMEM37,TIAM1,CPE,TUBA4A,VPS11,UXT,KDELR3,PRKAR2B,LOXL2,ICMT,RNF19B,ARF4,LCP1,SLC44A3,ENPP1,PLCG1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,RNASEL,ARF6,ANXA11,NXT2,SCN5A,NFKBIE,GGA1,SEC61G,ITGA6,SOX9,RAB23,SLC36A4,GPSM2,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,MEGF8,ATP5H,RIMS3,FLRT3,FBXO7,RANBP1,PCYOX1,CADPS2,CNGA1,PANX2,NUP85,C9orf72,PPP6R1,NAGPA,UFD1L,SLC37A1,KIF20A,MAPKAPK3,ERO1A,CALCRL,PLS1,KIF20B,SRSF5,ILK,PCTP,GOLT1A,SFXN5,RHOB,PLIN5,CYB5A,PTPRF,CACHD1,SCARB2,SLC4A4,TIMM8A,HTT,SEMA4D,ITPR1,DGAT2,AURKA,DYSF,OSCP1,NDE1,ARPC2,TRPC3,NUP58,XDH,MTM1,CCDC109B,INPP5D,APOO,C5orf30,PKP2,MVB12B,PRKACA,APC2,APPBP2,CCND1,SCNN1A,CDH1,ACSL4,ARL4D,DLG3,RAB27B,RASGEF1A,SNX10,TMEM9,SCN3A,SNX8,SEC61B,PSRC1,FZD4,SYNE2,VPS4B,HTATIP2,SYP,NUSAP1,RAB38,SNX12,PEX5,STX10,SHROOM3,CORO1C,SLC9A6,AXL,PRIMA1,RGS14,SLC25A30,TTC8,CTHRC1,TCAF1,MZT1,TAOK2,HSP90B1,SDC4,HABP4,FLOT1,BTN3A1,PDIA3,CTSZ,ANO9,PKN1,KCNC4,ETS1,GSTP1,IFT27,SLC25A43,TSPAN17,SRPX2,ICAM1,PDIA4,SGPL1,CXCL16,SLC25A45,ANK1,PDCD10,ADD3,SLC27A6,CTSC,FAM160A2,KCNK5,BAX,KLC3,PLEKHF1,WWP1,TPCN1,S100A6,PARP9,HCN3,ACBD5,MOB4,LCA5,TACC1,RAPGEF2,MFSD2B,PIK3R1,EIF5A2,MRS2,GRIN1,PGBD1,RAB3IP,FAM109A,NEURL1B,CNTNAP1,PITX2,RGPD5,BTG1,LDLRAP1,RPL12,RAB11FIP2,ACVRL1,SYT7,SLC35B3,DBI,NR4A3,ARFGAP3,SSNA1,ITGAV,CENPE,NUP37,CD81,USF2,WDR45B,SRSF9,CYBRD1,UNC93B1,ILDR1,TNK1,AGRN,EPHA4,ARFGEF1,NDC80,F11R,ITPR2,HDAC6,PDGFB,NUP62CL,SDC1,SUSD2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,ARL1,LMAN2L,MITF,SLC44A1,ABCA2,TLN2,ANO4,SCARA3,TRAM1,S100A13,PLK1,KCNIP3,MARK1,CELSR2,STAU2,EZR,ARFRP1,ESYT1,ANLN,CLCN2,CDK1,VCP,OPTN,TNS4,TRIM9,TRAM2,TBC1D17,KCNMB4,WIPI1,RAB11FIP1,KPNA2,PIEZO1,TC2N,RRAGD,PRKAA2,LGALS3,FXYD3,SLC22A31,RACGAP1,RAB6A,NCKAP1,CNTNAP2,PGAP1,ANO1,SSX2IP,CORO1B,B4GALNT1,RB1,TNS3,TIMP1,RINL,GATA2,FRAS1,ICAM5,KIF13B,PAK2,FCHO1,SLC30A6,EXOC8,SELK,NTN1,WNT3A,ABCC1,SPATA13,STRADB,SCRIB,EIF2AK1,ZDHHC3,NMT2,CDK5R1,MAPKAPK2,PVRL2,ITGA7,MFSD2A,SLC2A6,ZDHHC7,LTBP2,PLD1,ATP1B3,CDAN1,SEMA3A,NIPA1,RAD21,KCNAB3,UPF3B,TP53,P2RX7,SLC7A2,STIL,EMP2,BCAP31,SYTL2,SDF4,TTC21B,PDGFA,ATP6V0B,SRPX,TACC2,PLCG2,LHX6,BCL6,ZDHHC23,SCN2A,LMAN1,GM2A,DVL2,PPIF,CLCN3,AKT1,ACO1,DAG1,ATP13A2,TAPBP,ATP1A1,PTK7,MAOA,CHMP4B,SYT13,RPL22,CNEP1R1,POMGNT2,COPG1,ARFGEF3,BIN1,PINK1,MFSD14B,PACSIN2,GOLIM4,TRAPPC10,CD63,ADGRG1,CDCA8,GABRG2,SELL,PSMD10,CRABP2,AIP,VPS26A,SLC9A2,SIRPA,GBX2,M6PR,ZDHHC21,CDK16,SLC35B4,SGK1,ABCD1,CPLX1,SYK,SLC45A3,CAMK2G,ATP2B1,GCNT1,P2RX4,HES1,FBLN5,RHOA,CRB3,PPARA,PRICKLE1,COL7A1,AKAP3,BCAR1,BBS2,MAPK8IP1,SCRN2,SERPINA1,SCG2,TMC5,PKD2,SPCS3,NDFIP1,TBC1D4,ARHGEF9,SUN1,LAMP1,GAA,SLC35D2,ACVR1,HSPG2,TSC22D3,ATP8A1,KLC2,TAP1,GATA3,CCNB1,SLC20A1,RIC1,PICK1,NCS1,SLC9A7,PAK6,CTGF,STIM1,ELMO2,OSBPL3,STEAP2,KCNS3,SERINC2,PIK3CA,SNX16,MARCH2,PACSIN1,TFG,XKR8,LAMP2,ORAI2,ACVR1C,BNIP3L,SLC35C1,KIF13A,TNS1,SLC17A5,AURKB,MCFD2,SLC25A5,ZFAND5,SPNS3,RAB2B,SFXN1,SLC25A4,AREG,GNPTAB,TBX1,SARAF,F2RL1,SLC31A2,RTN3,SEMA6B,MRC2,INPPL1,SLC25A27,NDUFA4,SLC1A3,APBA1,S100A2,MESDC2,CALR,DOPEY2,ITGA3,CYR61,SNX18,NECAB3,SLC16A6,RPL39,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,SYTL3,TSPAN33,RIMS2,TMED2,TRAK2,DNAI1,EPB41L5,KCNJ12,GCC2,PMPCB,MFI2,CALM1,ANO6,NPC2,ATP8B3,CYFIP2,STX3,GABRD,AP1AR,SLCO4A1,PRKAG2,CSNK1G1,WDR19,ZDHHC20,MATN2,SLC4A3,FAM83D,NR4A2,EFNA1,PLIN3,HOOK1,NRBP1,EHD1,PKD1L2,PLA2G4A,MFSD3,KIF3C,SLC2A4,ARMCX3,DLGAP5,GPR107,TRIP10,THRA,RALBP1,ATP2C2,FTH1,CD274,EGR3,BCL2L1,DDR1,TMPRSS4,ZFYVE9,SLC25A35,NOV,ACAP2,CNNM4,TNPO2,CDKN1B,DAB2IP,PDE4D,IFIT1,EPHB4,OSBPL7,TSPAN1,FLOT2,TBC1D10B,SEMA3B,ATG4D,MYO5B,DOCK4,SEC23A,SLC5A11,COG2,DMTN,COX11,KIF1C,PRKCQ,SLC11A2,ATP1B1,PYGO1,ITPR3,ATP10D,NIN,OSBPL2,FYN,DDOST,JAK1,STAT1,SLC27A1,NRG1,RAB29,PRKAR1A,DENND5B,SLC16A14,ATP9A,SLC41A1,EPS8,ARL4C,CYB561,PLD2,SPDL1,DNAH3,EFNB1,FGF19,LGALS3BP,SIX4,COX7A2,SLC25A36,CKAP5,RNF128,PPP1R10,PTEN,FUT8,CD9,SGK3,ATP8B1,SLC44A2,TTPA,SLC16A5,SPRY2,NCOA2,ZWINT,CASK,ZC3H11A,DENND1B,FURIN,VAMP3,PARP4,YES1,CPTP,GPLD1,CRTC2,MAMDC4,CTNS,SEC14L4,FGFR2,RIN3,SLC25A40,ABCB1,GRIN2D,ARSB,SLC25A38,ESPL1,ESYT2,EXPH5,LTBP1,UGT8,FAF2,TMEM184B,CRYM,CPT2,UBE2Q1,MPP5,KIF2C,CACNB4,DNER,SLC8B1,ERP29,TMC1,SH3KBP1,ABCD4,MAGOHB,ZFYVE16,RAB15,LRRC6,CDKL5,DPYSL2,DLG1,TRPC1,SUN3,KIF22,RAB20,RP2,CTTN,SLC39A10,MYRIP,RASGRP1,CYP1B1,SOD1,CENPA,SYNE3,STRIP2,ACBD3,ADRBK2,TCN2,EDNRA,SEC14L2,MDK,KCNK1,UEVLD,APBA2,PCSK5,GRN,LASP1,ARAP3,BVES,PEX6,ETV5,ABCG2,ATP6V1E2,CALM3,SPP1,CA2,KCNN4,PRKCI,FXYD5,SRP54,BRAT1,ZRANB1,SLC12A2,GAD1,CCDC88A,MDFI,SNX7,KDELR1,PODXL2,BTN3A2,FBXO8,NUBP1,MFSD7,STEAP1,EGFR,GNAS,TSC1,SLC6A6,PLPP3,TMEM30A,NFKBIA,CDCA5,SH3BP4,RAB31,CTSA,PITPNA,SHROOM2,JAK3,TOB1,APOL2,SNX30,DRD1,DYNLRB1,SLC25A24,SORBS1,SLC2A8,ABCG4,MICALL2,ARHGEF16,SLC25A48,SVBP,ARTN,KIF14,ZDHHC12,REEP1,FABP6,SMO,TWIST1,DIXDC1,STEAP3,RPN2,F2R,SCYL3,UPF3A,CHP1,SOAT1,BAG4,PTPRU,SLC39A8,OSTM1,AP5M1,ERBB2IP,ALDH5A1,PEX2,SPTBN5,PLXND1,ABCA1,ANXA3,SORT1,TSPAN15,SH3D19,FRMD6,ARHGEF7,LRP4,TGFBR1,RBP7,HMGXB4,ITGA2B,TMEM63A,KIF5B,SNX13,ADORA1,ADRBK1,MLPH,LLGL2,BMP7,RRBP1,KIAA0319,ZDHHC13,H2AFY,TRIM3,SLC35A1,RPGR,MYO5A,SUN2,SYPL1,ADAM17,RAB3B,CFAP46,ASPM,NR4A1,MAP1B,ARHGAP24,SLC18B1,ARRB1,MCUR1,GEM,ATP6V1C1,PLOD3,CEP41,SOX8,L1CAM,RAB3IL1,ABCG1,SNPH |
| 2.503e-10 | -22.11 | cellular developmental process | biological process | GO:0048869 | 3526 | 646 | 16441 | 2455 |
ADD1,AK7,RET,MCOLN3,HEXB,CACNA2D2,CCNO,NRG2,GRM5,TP73,CALM2,NPM2,CDKN2C,WEE1,PSMD1,TGFBR3,PAQR5,RDH14,DNM2,PIK3CD,SEMA3G,TIPARP,TIAM1,DNAAF3,SMARCA2,SPEF2,TFAP2C,LOXL2,ARF4,COL12A1,PGF,PLCG1,DNM1L,LIMK1,TRAF3IP1,HDAC1,TMOD2,RNASEL,ITPKA,ARF6,E2F8,SCN5A,ALDH6A1,TMTC3,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,LMNA,ELF3,RAC2,FRY,FLRT3,MEGF8,ZIC5,NCAM1,MAPK7,DGKG,TTLL1,PAQR7,REC8,ERO1A,SHARPIN,FHL2,KIF20B,ILK,NPHP3,ELK1,TP53INP2,DPYSL4,PSMA4,RHOB,PTPRF,ETS2,SEMA4D,HTT,CLMN,AURKA,B4GAT1,GDF11,ARPC2,CFAP20,NDE1,TRPC3,CSRP2,RPS6KA3,MTM1,GRHL2,LFNG,C5orf30,APC2,PRKACA,TNFSF9,CCND1,CDH1,DACT1,ACSL4,DLG3,RASGEF1A,SNX10,ETV4,MYT1,SSH3,CAMSAP3,COL6A2,LGALS8,FZD4,HTATIP2,RAB38,TANC1,EBF2,NFIX,IRS2,SHROOM3,SLC9A6,AXL,CORO1C,SIPA1L1,WWTR1,RGS14,ARNT,MAPK12,TTC8,CTHRC1,FARP1,RBM24,SDC4,CCM2,FLOT1,GMCL1,PLPPR4,ETS1,ICAM1,NEO1,SGPL1,CAPN2,ANK1,IGSF9,KNDC1,GPC3,CST3,BAX,ADAM15,MAPK11,RAG1,SGCB,ITM2C,S100A6,FMN1,TACC1,BCL9,RAPGEF2,PIK3R1,GRIN1,RAB3IP,ABLIM2,TXK,PITX2,CNTNAP1,PROM1,ACVRL1,NR4A3,ITGAV,FHL1,OSR1,SHOX2,FOXA1,TLL2,MYL9,TNK1,EPAS1,AGRN,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,SDC1,PDGFB,SPTB,PLS3,PCNA,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,MITF,PSMC2,ELF5,TMEM143,DUSP10,NTN4,THRB,MARK1,CELSR2,NFE2L1,EZR,CR2,KLK6,ANLN,ZBTB7B,CLCN2,CDK1,RHEB,DZIP1L,DPYSL3,IRX3,HS6ST1,MAP2,MYL12B,MAFF,USH1C,RUNX2,LGALS3,RASA2,PSMD7,RACGAP1,CNTNAP2,IL18R1,SSX2IP,BMP2,RB1,VASP,DAZAP1,IGF1R,GATA2,KIF13B,PAK2,WNT3A,NTN1,PSMA5,CYP26B1,DPYSL5,RGMB,STRADB,TCF7,SCRIB,EIF2AK1,UNC45B,CDK5R1,FOXD2,FA2H,PVRL2,COL13A1,MFSD2A,ITGA7,CSF1,TMEM120A,AKIP1,SEMA3A,CTBP1,HOXB7,NF2,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,STIL,SDF4,PER2,TTC21B,PDGFA,TACC2,LMO4,LHX6,PLCG2,PLK4,BCL6,CDH3,NOTCH3,SULF2,SIRT1,TIMP2,AKT1,FIGNL1,S100A4,CDC20,PTGER4,MYL12A,DAG1,PTGS2,PTPRJ,RTN4RL1,PTK7,PSMD3,EFNA5,RPL22,LTA4H,POMGNT2,CTDSP1,BIN1,COL9A3,DYRK3,PACSIN2,ADGRG1,CD63,CTSB,PSMD10,GDF15,JAG2,CRABP2,NRP2,PPP2R3A,GBX2,CD109,CDK16,TFAP2A,UBE2J1,SGK1,SYK,TLE6,FAM134C,CAMK2G,HES1,RHOA,PSMB4,STMN3,COL7A1,FNDC3A,BBS2,CNOT2,FAT4,TWSG1,FGF18,PGRMC1,CFAP74,ACVR1,LGR4,SSH1,HSPG2,GATA3,PSME1,CAMK1D,PLXNA1,CCNB1,SEPT4,FAM101B,NCS1,PICK1,TYMP,CYP1A1,CTGF,IL31RA,PACSIN1,ZBTB18,ACVR1C,CASP9,SAV1,ULK2,ARHGEF26,SFXN1,HLF,AREG,PLK2,PTER,TBX1,NKD1,BMP1,DHTKD1,UNC5B,F2RL1,LZTS1,KLF2,SEMA6B,MRC2,CDKN1C,SLC1A3,NOTCH2,HERC6,KIAA1161,MECOM,CALR,ITGA3,CYR61,BHLHE41,MSH2,PRKG1,SORL1,TNFRSF12A,CACNA1D,PIKFYVE,RIMS2,DNAI1,EPB41L5,SPATA20,MMD,B9D2,CEP89,DCHS1,AMER1,CALM1,EPHA1,KDM3A,ANTXR1,NFIB,STX3,RASA1,FAS,MMP15,NAB2,MATN2,WDR19,FAM83D,SFMBT1,NR4A2,EFNA1,HOOK1,EHD1,IRF1,ELK4,FOXO6,SPRED1,SLC2A4,TCTN2,ST14,RPS6KA1,CAST,IQGAP1,THRA,NDRG1,BCL2L1,FLT3,NOV,DAB2IP,PDE4D,EPHB4,SEMA3B,DMTN,FOXJ2,SLC11A2,PRKCQ,PYGO1,ALCAM,FZD7,CMTM7,CEP162,EPHA10,FYN,JAK1,STAT1,KLF5,RAB29,NRG1,COBL,ATMIN,PRKAR1A,WASF3,NES,PBX3,SPR,FGF19,EFNB1,SIX4,TEAD3,RND1,E2F7,PTEN,CD9,ATP8B1,TAGLN2,ERCC2,ERBB3,CITED2,GFI1,SPRY2,OSGIN1,FARP2,RASGRF1,TGIF1,ARHGEF28,B3GNT2,TCFL5,VAMP3,DIAPH2,C1GALT1C1,FBXO9,YES1,FOS,GPLD1,CDK5RAP1,FGFR2,PRDX3,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,WDR62,FZD5,ARSB,SLC25A38,JARID2,RGMA,EXPH5,CASP3,EMX1,UGT8,MPP5,DNER,CACNB4,TMC1,EPCAM,LRRC6,CDKL5,DPYSL2,IMPAD1,DLG1,TRPC1,RP2,MYH14,CTTN,BTBD3,RASGRP1,ATL1,SOD1,FOPNL,RNF165,EDNRA,MDK,GPRC5B,TDRD7,PSMC1,NR2C2,GRN,SERPINE2,BVES,ETV5,CALM3,TEC,DUSP5,SPP1,LRRN2,FAM20C,OCRL,COL6A1,PRKCI,FNIP1,C10orf54,NPTN,ETV7,CCDC88A,MDFI,ELK3,HMG20B,RANBP9,EGFR,FECH,TSC1,ONECUT1,UTP14C,PLPP3,TMEM30A,EGFL7,PITPNA,SHROOM2,JAK3,RARG,KLF7,DRD1,PAX6,IL15,PSME2,HDAC11,COL18A1,TDRKH,ZMYND10,OSR2,MICALL2,PHLDA1,EXT2,SS18,ARTN,KIF14,FRYL,SMO,TWIST1,DIXDC1,NFKB2,HSPA2,FRS3,SOAT1,PTPRU,OSTM1,GLO1,SOCS3,ARHGAP35,HSF4,BFSP1,BHLHB9,STAT6,PEX2,PTBP3,SPTBN5,PLXND1,LIFR,SORT1,ARHGEF11,POC1B,ARHGEF7,FRMD6,CIT,LRP4,TGFBR1,COL4A5,ITGA2B,HDAC9,KIF5B,TOP2A,LLGL2,MYCL,BMP7,RRBP1,KIAA0319,ACTA2,RPGR,MYO5A,ADAM17,WNT10B,CFAP46,ASPM,NR4A1,RC3H2,RUNX3,NDRG3,FOXL1,SPAG1,MAP1B,ARHGAP24,LEMD2,CD8A,DHRS2,SPINT2,RAP2C,CTSV,HOXB13,ZMIZ1,SOX8,PLOD3,CEP41,L1CAM,NGEF |
| 2.869e-10 | -21.97 | PEREZ_TP53_AND_TP63_TARGETS | MSigDB lists | PEREZ_TP53_AND_TP63_TARGETS | 191 | 62 | 17758 | 2588 |
COL9A3,TNRC6C,CDKN1C,SLC16A14,NUAK1,ZCCHC24,TSC22D3,BIK,RET,COL18A1,GMCL1,MICALL2,SEPP1,DHRS3,APC2,RBP7,FAM46C,PGAP1,SLC35E4,CHST2,TMEM63A,BMP2,PAK6,SUSD2,SIPA1L2,IGF1R,FRY,DOK4,VASN,REEP1,CNNM4,EPB41L4B,C10orf54,NOTCH3,MOXD1,NTN1,ULBP2,MYLIP,RASGRP1,MX1,KCNJ12,TAF5,TRIM8,LONRF3,TACC1,SPATA13,GRTP1,DPYSL4,GNA11,CRISPLD2,RHOB,PGF,HS6ST1,PTPRJ,INSR,SEMA4D,FGF18,RAB11FIP1,ARRB1,SOX8,UNC5B,PCSK5 |
| 2.870e-10 | -21.97 | PROTEIN_KINASE_ATP | prosite domains | PS00107 | 378 | 104 | 11866 | 1802 |
TNK1,ACVR1,CAMKK1,RPS6KA1,EPHA4,RET,ERBB2,TESK2,MAPK4,CAMK1D,GRK6,FLT3,PRKACA,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CDKL5,PASK,PLK4,EPHB4,STK35,PLK1,NEK4,MARK1,AKT1,ACVR1C,PRKCQ,PKMYT1,AURKB,MAP3K6,ADRBK2,STK17B,CDK1,ULK2,FYN,JAK1,STK26,CDK19,PLK2,STK38,LIMK1,AXL,MYLK,KIAA1804,MAP3K11,MAPK13,MAPK12,PRKAA2,CDK17,TAOK2,LMTK3,DYRK3,NUAK1,CIT,PRKAA1,TGFBR1,TEC,PKN1,MERTK,ADRBK1,IRAK1,IGF1R,CDK16,PAK2,PRKCI,SGK3,DAPK1,PRKG1,MAP3K9,SGK1,MAPK11,BUB1,PIM1,MAP3K7,MAPK7,PHKG2,SYK,CAMK2G,MAPKAPK3,TESK1,EIF2AK1,YES1,EPHA1,PIM3,PDIK1L,EGFR,TXK,STK17A,MAPKAPK2,INSR,FGFR2,ACVRL1,CSNK1G1,AURKA,CDK18,STK39,MAP3K5,JAK3,HIPK3,MELK,RPS6KA3,DMPK |
| 3.160e-10 | -21.88 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | 578 | 140 | 17758 | 2588 |
AGRN,CNOT8,XIAP,SDC1,CHST2,BTG3,GRHL1,P4HB,ARNT2,BTBD3,CPE,ANKRD9,LAMP2,ASXL1,SH3BGRL,BNIP3L,KDELR3,TNS1,LOXL2,SAV1,IRX3,WDR11,DHRS13,LRIG1,FAM110C,KLF11,UNC5B,TC2N,CAPN1,RRAGD,ZNF395,HLA-E,HLA-F,NCKAP1,ELF3,MESDC2,SPP1,OTUD1,RAC2,TIMP1,COL6A1,EBF4,SORL1,HLA-C,IGSF3,KCNJ12,WDR72,SRSF5,NPHP3,KDM3A,IL1R1,SLCO4A1,CACHD1,SLC6A6,SERTAD2,INSR,FNTA,FA2H,ETS2,NAB2,RAB31,NXPH4,NR4A2,SAMD8,SERPINB1,AFAP1,XDH,EGLN1,UGP2,PAPSS2,CAST,NDRG1,SOD2,FTH1,SLC7A2,SNN,TMPRSS4,CYHR1,CDH1,BCL6,GYS1,PDE4D,RAB27B,EGLN3,TSPAN1,CPD,ERMP1,TMEM43,SYNE2,SOCS3,OSBPL2,PTGS2,TAPBP,STAT6,MAOA,KLF5,CHMP4B,RPL22,LTA4H,CBX4,PRKAR1A,ENO2,SLC16A14,ARHGEF7,AES,COL4A5,JAG2,SEPP1,NRP2,SLC25A36,CXCL16,ADD3,ITGB8,PTEN,ATP8B1,AK3,CITED2,DUSP1,PGM1,ADAM17,GUSB,TCFL5,LITAF,PPARA,FBXO9,FNDC3A,FOS,FUCA1,DCAF10,HLA-B,KIAA0141,PLOD2,TMC5,ARFGAP3,GRAMD1C,ZMIZ1,AHR,CYBRD1,ZBTB33,ESYT2 |
| 3.248e-10 | -21.85 | PH_DOMAIN | prosite domains | PS50003 | 247 | 76 | 11866 | 1802 |
PLEKHG3,FAM129B,SPTB,ARHGEF16,ACAP2,ARHGAP42,OSBPL3,PLCG2,DNM2,DAB2IP,RTKN2,OSBPL7,TIAM1,AKT1,SNTB2,PLEKHO1,ANLN,ADRBK2,ARHGEF26,ABR,PLEKHB1,IRS2,PLCG1,PLCH1,PLEKHG6,ARHGEF19,MPRIP,TRIOBP,PLEKHG1,SPTBN5,GAB1,FGD1,FARP1,ARHGEF3,ARAP3,ARHGEF11,PLEKHJ1,ARHGEF7,CIT,RASA2,TEC,SBF1,DOCK11,PHLPP1,ARHGEF40,SNTA1,ADRBK1,RALGPS2,MCF2L,EXOC8,PLEKHF1,CADPS2,FARP2,RASGRF1,PLEKHA6,ARAP2,ARHGEF28,PHLDB3,SPATA13,PLEKHA7,SNTB1,FAM109A,RASA1,ARHGAP24,DGKH,SWAP70,PLEKHH2,APPL2,ARAP1,FGD6,AFAP1,ARHGEF9,DEF6,NGEF,DOCK9,ARHGEF4 |
| 3.472e-10 | -21.78 | regulation of protein phosphorylation | biological process | GO:0001932 | 1334 | 280 | 16441 | 2455 |
TXN,ACVR1,IBTK,GRIK2,TRIM5,DNAJC3,NRG2,PSME1,IL18,CCNB1,SNX9,CARD10,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,CTGF,RGS3,IL31RA,PIK3CA,NEK4,TNIP1,PBK,PRKAR2B,ENPP1,PLCG1,CAMK2N2,ANKRD6,TBX1,TRAF3IP1,NOD2,MAP3K11,SPRY4,HSPB1,F2RL1,GAB1,CDKN1C,SOX9,PRKAA1,MECOM,TFAP4,RAC2,CYR61,FBXO7,MAP3K9,SORL1,MYDGF,NCAM1,SOCS5,MMD,MAPKAPK3,CALM1,EPHA1,ILK,PSMA4,RASA1,FAS,PRKAG2,SEMA4D,PELI2,FAM83D,STK39,EFNA1,GDF11,MAP3K5,XDH,SPRED1,IQGAP1,PRKACA,FLT3,CCND1,APLP2,ST5,CCNA2,RALB,DACT1,CDKN1B,DAB2IP,PDE4D,RASGEF1A,CDKN2D,PSRC1,RIPK2,FZD4,DMTN,PKMYT1,FZD7,IRS2,FYN,JAK1,CCNB3,STK26,CORO1C,WWTR1,KIAA1804,SLC27A1,NRG1,RGS14,PRKAR1A,NKX3-1,TAOK2,TRAF2,SDC4,FLOT1,HERC5,PKN1,GSTP1,FGF19,ICAM1,DIRAS3,PDCD10,IRAK1,PTEN,KNDC1,BAX,MAPK11,ERBB3,MAP3K7,SPRY2,RASGRF1,PDGFC,RAPGEF2,GRIN1,YES1,CDK5RAP1,FGFR2,ACVRL1,RYK,GRIN2D,GPER1,CENPE,LRRK1,FZD5,CD81,CCNC,CASP3,CAMKK1,EPHA4,NDRG2,NENF,ERP29,PDGFB,SPTB,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,DLG1,DUSP10,TNFRSF18,RASGRP1,PLK1,SOD1,ITCH,EZR,CDK1,KDM4D,GPRC5B,MADD,PRKCDBP,CAB39,PSMC1,RASA2,UBASH3B,PSMD7,CALM3,SORBS3,TEC,PHLPP1,FBLN1,DUSP5,BMP2,RB1,IGF1R,PAK2,FNIP1,BRAT1,MDFIC,NPTN,PIM1,WNT3A,PSMA5,CCDC88A,MDFI,STRADB,PDE5A,EIF2AK1,RANBP9,CDK5R1,EGFR,BCAR3,MAPKAPK2,FECH,TSC1,INSR,CSF1,PLPP3,JAK3,PROM2,DRD1,CCNE2,AVPI1,NF2,IL15,FOXM1,PSME2,CTDSPL,TP53,P2RX7,ERBB2,RASGRP3,CCNL1,STIL,EMP2,PDGFA,KIF14,TWIST1,APIP,F2R,CTDSP2,HSPA2,DVL2,CKS2,CHP1,FRS3,SIRT1,MAP3K3,BAG4,TIMP2,AKT1,CD40,DUSP4,CDC25C,MAP3K6,DAG1,C3orf33,SOCS3,DNAJC10,PTPRJ,STK38,PSMD3,SPTBN5,EFNA5,CTDSP1,PINK1,TAB3,LRP4,PSMD10,GDF15,TGFBR1,TRIB2,CD109,ADORA1,BMP7,H2AFY,CKS1B,HEXIM2,IQGAP3,SYK,CAMK2G,DUSP1,HES1,ADAM17,PSMB4,PLAUR,RGCC,MAPK8IP1,LEMD2,BANK1,RAP2C,FGF18,ARRB1,PKD2,PPP2R3C,UBE2C,HIPK3,PKIA |
| 3.531e-10 | -21.76 | adherens junction | cellular component | GO:0005912 | 471 | 120 | 17570 | 2579 |
LMO7,SORBS1,KIAA1462,NF2,ADD1,HSPG2,FAM129B,NDRG1,IQGAP1,PKP2,SDC1,SLC9A3R2,GNB2,SH3KBP1,CD46,ZYX,CDH1,CTNNB1,P4HB,DLG1,DNM2,IRF2,CDH3,KIF22,DIXDC1,CTTN,TLN2,FLOT2,SMAGP,CHP1,CAMSAP3,LAP3,SNTB2,SYNE2,EZR,TNS1,ALCAM,DAG1,LCP1,TNS4,MPRIP,JAK1,SHROOM3,CORO1C,PTK7,LIMK1,TRIOBP,PPP1CB,SPRY4,ARF6,RPL22,HSPB1,CAPN1,CD99,LASP1,FBLIM1,PACSIN2,HSP90B1,MRC2,MPZL1,PPP1R12A,ITGA6,ARHGEF7,SDC4,FLOT1,PDIA3,KIF23,SORBS3,NCKAP1,ICAM1,ITGA2B,SSX2IP,RND1,CORO1B,CALR,CAPN2,RAC2,TNS3,FLII,VASP,ITGA3,FLRT3,TBCD,CD9,ADAM15,EPB41L5,PVRL4,DCAF6,ADAM17,RHOA,CASK,FMN1,PLAUR,PLEKHA7,FHL2,SCRIB,VEZT,YES1,SNTB1,AIF1L,ILK,BCAR1,RHOB,EGFR,ARHGAP24,SCARB2,RPL12,RND3,PVRL2,PLPP3,ITGA7,ITGAV,FHL1,HMGA1,ARPC2,SHROOM2,CD81,AFAP1,L1CAM,CSRP2 |
| 3.712e-10 | -21.71 | microtubule cytoskeleton | cellular component | GO:0015630 | 1041 | 225 | 17570 | 2579 |
KLC2,XIAP,NDRG2,F11R,CNTROB,KIF2C,SYTL4,CCNB1,HDAC6,MAP1LC3B,KIF26A,PHF1,CALM2,PCNA,RPS6KA2,CTNNB1,STIM1,CNTRL,DNAH6,DPYSL2,CEP78,DDHD2,CAPG,DLG1,DNM2,ABCA2,TUBG1,KIF22,HYLS1,RP2,CTTN,ZBTB18,ODF2L,CCDC38,TUBA4A,PLK1,SPEF2,PCGF5,MARK1,KIFC2,SNTB2,STAU2,FOPNL,UXT,EZR,CKAP2L,KLK6,PRKAR2B,KIF13A,AURKB,CCNF,SLC25A5,CDK1,DZIP1L,PLEKHG6,NEIL1,MID1IP1,CAMK2N2,WDR11,DNM1L,MAP2,PLK2,TRAF3IP1,FAM110C,MAP3K11,RELL1,HSPB1,TRAF5,ANXA11,PIFO,PPP1R12A,NUAK1,CALM3,KIF23,RACGAP1,TXNDC9,SSX2IP,FLII,RB1,FRY,KIF13B,TBCD,NEK2,PRKCI,SLAIN2,KNTC1,LRIF1,MPHOSPH9,NUP85,TTLL1,TPGS2,C9orf9,DNAI1,KIF20A,CEP89,B9D2,CALM1,KBTBD8,KIF20B,NUBP1,RANBP9,MAPKAPK2,FNTA,HTT,AGBL5,FAM83D,AURKA,MDH1,NDE1,CFAP20,KIF12,SHROOM2,HOOK1,CCNB2,RUSC1,GAS2L1,KIF3C,DYNLRB1,SORBS1,CEP70,DLGAP5,UPF3B,TUBB4B,RPS6KA1,ACTR8,IQGAP1,NDRG1,ZMYND10,BCL2L1,PRKACA,APC2,STIL,APPBP2,LRRC45,SS18,TACC2,KIF14,PLK4,PDE4D,ZNF365,SNX10,CHP1,CAMSAP3,PSRC1,AKT1,CAPN6,SEPT6,CCSAP,CDC20,VPS4B,KIF1C,NUSAP1,SP4,GABARAPL1,NIN,CEP162,SHROOM3,STK26,TRIOBP,SPTBN5,RGS14,SGOL1,MAD2L1BP,REEP4,GEN1,TTC8,MZT1,CKAP2,POC1B,RASSF7,FLOT1,ERCC6L,CDCA8,SPDL1,DNAH3,IFT27,SAC3D1,CKAP5,KIF5B,CCDC92,TOP2A,MZT2A,CEP97,TBC1D31,PHF7,CDK16,CENPJ,TUBGCP6,GTF2F2,PRC1,TFAP2A,KLC3,ERCC2,CLIP2,RPGR,SPRY2,MYO5A,LCA5,TACC1,FMN1,ASPM,SYBU,PLEKHA7,PARP4,RGCC,RAB3IP,YES1,SKA1,BBS2,KIF11,SPAG1,MAP1B,BCL10,DCTN6,NUCB1,PPP2R3C,SSNA1,PKD2,CENPE,GEM,WDR62,CEP41,ESPL1,DIS3L,SNPH |
| 3.755e-10 | -21.70 | GNF2_RRM2 | MSigDB lists | GNF2_RRM2 | 40 | 23 | 17758 | 2588 |
HMMR,PLK1,ZWINT,DLGAP5,FOXM1,ASPM,CDC20,NDC80,CDCA8,NUSAP1,AURKB,KIF11,CDK1,TOP2A,CCNA2,PCNA,AURKA,BUB1,CENPE,UBE2C,CCNB2,ESPL1,MELK |
| 3.774e-10 | -21.70 | breast-carcinoma-ER-PR-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-PR-positive_carcinoma | 1940 | 376 | 17775 | 2585 |
ACACB,ACVR1,TRIM24,RET,XIAP,DHX8,GATA3,NRG2,LACTB2,CARD10,GRM5,CHST2,EPDR1,CDKN2C,PAK6,WEE1,CYP1A1,PSMD1,DNAH6,FOSB,PIK3CA,PPP1CA,PIK3CD,TFG,TIAM1,TIPARP,ACVR1C,CASP9,TMEM151A,PRKAR2B,AURKB,SAV1,PPP1R14C,CCNF,POR,LCP1,PIAS3,PLCG1,TRIM47,AREG,PPP2R4,LRIG1,MAP3K11,DHTKD1,HDAC1,MAPK13,SPRY4,TRAF5,HSPB1,GAB1,HOXC13,DDX58,INPPL1,PRKAA1,RAB23,NOTCH2,MERTK,PSIP1,MECOM,RAC2,ZNRF2,CD22,NEK2,MSH2,USP1,USP38,FAM84B,MAPK7,SOCS5,DDB2,STAT4,AMER1,SHARPIN,WHSC1,CALCRL,PLS1,ELK1,FBXO10,GNA11,RHOB,RASA1,FAS,IL1R1,PRKAG2,ETS2,FAAH,ITPR1,PIAS2,FAM83D,FGD6,AURKA,NDE1,MAP3K5,RPS6KA3,XDH,PLA2G4A,ELK4,SPRED1,LFNG,IQGAP1,SUZ12,RALBP1,RNF182,BCL2L1,PRKACA,FLT3,DDR1,KTN1,REPS1,CD46,CCND1,CCNA2,MUC16,CDH1,RALB,CDKN1B,EPHB4,RNASEH2A,ETV4,FLOT2,SCN3A,FZD4,SEPT6,CLSTN1,PRKCQ,PKMYT1,C15orf39,CBL,ITPR3,AKR1E2,ZNF469,FZD7,PRDM11,EPHA10,IRS2,FYN,PPP2R5A,JAK1,SHROOM3,AXL,STAT1,PPP1CB,NRG1,B4GALT3,ARNT,MAPK12,PRKAR1A,OTUD5,FARP1,IGFBP6,PARP14,TRAF2,HERC5,CTSZ,PKN1,ETS1,FGF19,HLA-A,WWP2,RND1,PDIA4,SCML1,CAPN2,DTX3L,DIRAS3,PDCD10,FUT2,IRAK1,ANKS1B,CTSC,PTEN,GPC3,FDXR,FJX1,SGK3,BAX,ATP8B1,WWP1,IGFBP2,MAPK11,ERCC2,ERBB3,MAP3K7,SPRY2,NCOA2,MSH6,PARP9,PVRL4,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,UBE2A,FURIN,C2orf69,LRRC1,FOS,CNTNAP1,BTG1,RGS9,CCDC6,FGFR2,RIN3,PPM1H,GRIN2D,FZD5,USP16,UNKL,CASP3,UGT8,PPM1J,EPHA4,PHOSPHO1,PDGFB,DNER,KREMEN1,RPS6KA2,CTNNB1,CNTRL,MKRN3,IMPAD1,PSMC2,MITF,DUSP10,NTN4,TLN2,MYBL1,S100A13,PLK1,CELSR2,ASXL1,USP18,ACBD3,ITCH,ROR1,IDH1,LHFPL2,ADRBK2,RHEB,EDNRA,MAN2A2,NEIL1,GPRC5B,HOXA9,RAB11FIP1,PIK3C2B,RAP1GAP,PPP2R5D,PRKAA2,LASP1,PARP12,RASA2,ETV5,PSMD7,DUSP5,BMP2,OTUD1,RB1,IGF1R,GATA2,ICAM5,PRKCI,BRAT1,PIM1,ZRANB1,ELK3,PLEKHA6,USP31,KBTBD8,SCRIB,HEATR5A,STEAP1,EGFR,G2E3,GNAS,MAPKAPK2,TSC1,INSR,OTUD6B,NFKBIA,ALPK3,YOD1,EGFL7,PLD1,JAK3,RARG,USP43,LMO7,PAX6,NF2,HOXB7,HDAC11,TP53,P2RX7,ERBB2,RASGRP3,MRAS,CCNL1,STIL,EXT2,PDGFA,SS18,PLCG2,SRR,SMO,BCL6,CDH3,GYS1,TWIST1,NOTCH3,NFKB2,DVL2,UPF3A,MAP3K3,KREMEN2,AKT1,PTGER4,CD40,DUSP4,CDC25C,FANCE,CASP4,DAG1,MAP3K6,SOCS3,PTK7,STK38,STAT6,ABCA1,LIFR,CTDSP1,CMAS,MACC1,SHPRH,FRMD6,MCTP2,TGFBR1,JAG2,PPP2R3A,FZD6,SIRPA,MYCL,BMP7,SGK1,BUB1,HSPA13,SYK,RPGR,DUSP1,HES1,PHF20L1,ADAM17,RHOA,WNT10B,AMFR,ASPM,RC3H2,OGDHL,MAML2,BCAR1,MAPK8IP1,MAP1B,BCL10,USP6,CASP7,FAT4,RND3,NEIL3,RAP2C,FGF18,DTX4,OTUB2,ARRB1,GEM,ABCG1 |
| 3.774e-10 | -21.70 | ER-PR-positive_carcinoma | COSMIC cancer mutations | ER-PR-positive_carcinoma | 1940 | 376 | 17775 | 2585 |
ACACB,ACVR1,TRIM24,RET,XIAP,DHX8,GATA3,NRG2,LACTB2,CARD10,GRM5,CHST2,EPDR1,CDKN2C,PAK6,WEE1,CYP1A1,PSMD1,DNAH6,FOSB,PIK3CA,PPP1CA,PIK3CD,TFG,TIAM1,TIPARP,ACVR1C,CASP9,TMEM151A,PRKAR2B,AURKB,SAV1,PPP1R14C,CCNF,POR,LCP1,PIAS3,PLCG1,TRIM47,AREG,PPP2R4,LRIG1,MAP3K11,DHTKD1,HDAC1,MAPK13,SPRY4,TRAF5,HSPB1,GAB1,HOXC13,DDX58,INPPL1,PRKAA1,RAB23,NOTCH2,MERTK,PSIP1,MECOM,RAC2,ZNRF2,CD22,NEK2,MSH2,USP1,USP38,FAM84B,MAPK7,SOCS5,DDB2,STAT4,AMER1,SHARPIN,WHSC1,CALCRL,PLS1,ELK1,FBXO10,GNA11,RHOB,RASA1,FAS,IL1R1,PRKAG2,ETS2,FAAH,ITPR1,PIAS2,FAM83D,FGD6,AURKA,NDE1,MAP3K5,RPS6KA3,XDH,PLA2G4A,ELK4,SPRED1,LFNG,IQGAP1,SUZ12,RALBP1,RNF182,BCL2L1,PRKACA,FLT3,DDR1,KTN1,REPS1,CD46,CCND1,CCNA2,MUC16,CDH1,RALB,CDKN1B,EPHB4,RNASEH2A,ETV4,FLOT2,SCN3A,FZD4,SEPT6,CLSTN1,PRKCQ,PKMYT1,C15orf39,CBL,ITPR3,AKR1E2,ZNF469,FZD7,PRDM11,EPHA10,IRS2,FYN,PPP2R5A,JAK1,SHROOM3,AXL,STAT1,PPP1CB,NRG1,B4GALT3,ARNT,MAPK12,PRKAR1A,OTUD5,FARP1,IGFBP6,PARP14,TRAF2,HERC5,CTSZ,PKN1,ETS1,FGF19,HLA-A,WWP2,RND1,PDIA4,SCML1,CAPN2,DTX3L,DIRAS3,PDCD10,FUT2,IRAK1,ANKS1B,CTSC,PTEN,GPC3,FDXR,FJX1,SGK3,BAX,ATP8B1,WWP1,IGFBP2,MAPK11,ERCC2,ERBB3,MAP3K7,SPRY2,NCOA2,MSH6,PARP9,PVRL4,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,UBE2A,FURIN,C2orf69,LRRC1,FOS,CNTNAP1,BTG1,RGS9,CCDC6,FGFR2,RIN3,PPM1H,GRIN2D,FZD5,USP16,UNKL,CASP3,UGT8,PPM1J,EPHA4,PHOSPHO1,PDGFB,DNER,KREMEN1,RPS6KA2,CTNNB1,CNTRL,MKRN3,IMPAD1,PSMC2,MITF,DUSP10,NTN4,TLN2,MYBL1,S100A13,PLK1,CELSR2,ASXL1,USP18,ACBD3,ITCH,ROR1,IDH1,LHFPL2,ADRBK2,RHEB,EDNRA,MAN2A2,NEIL1,GPRC5B,HOXA9,RAB11FIP1,PIK3C2B,RAP1GAP,PPP2R5D,PRKAA2,LASP1,PARP12,RASA2,ETV5,PSMD7,DUSP5,BMP2,OTUD1,RB1,IGF1R,GATA2,ICAM5,PRKCI,BRAT1,PIM1,ZRANB1,ELK3,PLEKHA6,USP31,KBTBD8,SCRIB,HEATR5A,STEAP1,EGFR,G2E3,GNAS,MAPKAPK2,TSC1,INSR,OTUD6B,NFKBIA,ALPK3,YOD1,EGFL7,PLD1,JAK3,RARG,USP43,LMO7,PAX6,NF2,HOXB7,HDAC11,TP53,P2RX7,ERBB2,RASGRP3,MRAS,CCNL1,STIL,EXT2,PDGFA,SS18,PLCG2,SRR,SMO,BCL6,CDH3,GYS1,TWIST1,NOTCH3,NFKB2,DVL2,UPF3A,MAP3K3,KREMEN2,AKT1,PTGER4,CD40,DUSP4,CDC25C,FANCE,CASP4,DAG1,MAP3K6,SOCS3,PTK7,STK38,STAT6,ABCA1,LIFR,CTDSP1,CMAS,MACC1,SHPRH,FRMD6,MCTP2,TGFBR1,JAG2,PPP2R3A,FZD6,SIRPA,MYCL,BMP7,SGK1,BUB1,HSPA13,SYK,RPGR,DUSP1,HES1,PHF20L1,ADAM17,RHOA,WNT10B,AMFR,ASPM,RC3H2,OGDHL,MAML2,BCAR1,MAPK8IP1,MAP1B,BCL10,USP6,CASP7,FAT4,RND3,NEIL3,RAP2C,FGF18,DTX4,OTUB2,ARRB1,GEM,ABCG1 |
| 4.126e-10 | -21.61 | whole membrane | cellular component | GO:0098805 | 1942 | 379 | 17570 | 2579 |
LAMP1,SUN1,ACACB,GAA,GRIK2,ATP8A1,RET,SYTL4,PJA2,SLC9A7,PICK1,NCS1,NAPG,PQLC2,AP1M2,CABP1,SLC46A1,RDH14,STEAP2,DNM2,CLDN4,SNX16,TACSTD2,MARCH2,PACSIN1,CPE,LAMP2,VPS11,SGCE,SPATA18,SNTB2,BNIP3L,MGAM,PRKAR2B,KIF13A,SLC17A5,MCFD2,ULK2,ARF4,LCP1,ENPP1,WDR11,GRID2IP,DNM1L,AREG,ATP7B,NOD2,SPRY4,UNC5B,ARF6,LZTS1,DDX58,SCN5A,GGA1,HLA-E,TMEM55B,ITGA6,PRKAA1,RAB23,SLC36A4,SLC1A3,FAM21C,MARCH8,RAC2,ITGA3,SNX18,ZNRF2,VASN,FLRT3,PCYOX1,CNGA1,PIKFYVE,CTSD,TMED2,RIMS2,GPR161,EPB41L5,MMD,ATP8B3,ANTXR1,GNA11,STX3,RHOB,CYB5A,FAS,GABRD,SCARB2,TJP3,SLC4A4,ITPR1,APPL2,OSMR,OSCP1,STK39,MAL2,PLIN3,RUSC1,TMEM173,DMPK,EHD1,SPRED1,SLC2A4,ARMCX3,TCTN2,NLRX1,ST14,NDRG1,KCTD12,BCL2L1,MVB12B,SNN,AIFM2,PRKACA,APC2,GNB2,REPS1,EPS8L2,ZFYVE9,CD46,ACAP2,SCNN1A,CDH1,CNNM4,ACSL4,PDE4D,TSPAN1,DLG3,RAB27B,FLOT2,SNX10,TMEM9,TMBIM1,SNX8,SEC23A,AGPS,FZD4,DMTN,SYNE2,CYS1,VPS4B,UTRN,CLSTN1,SYP,SLC11A2,ATP1B1,RAB38,CBL,TANC1,ITPR3,GABARAPL1,PEX5,FYN,SHROOM3,STK26,SLC9A6,CORO1C,SIPA1L1,SLC27A1,NRG1,RGS14,PRKAR1A,TTC8,BACE1,ATP9A,TRAF2,EPS8,SDC4,FLOT1,EFHD2,PLD2,EFNB1,SRPX2,ICAM1,HLA-A,CAPN2,SNTA1,ANK1,IRAK1,ANKS1B,PTEN,CD9,BAX,DRAM1,SLC44A2,ATP8B1,PLEKHF1,IGFBP2,ERBB3,MAP3K7,ITM2C,SPRY2,TPCN1,AMOTL2,ACBD5,CASK,PLSCR1,RAPGEF2,GRIN1,VAMP3,FURIN,AIF1L,CPTP,GPLD1,PROM1,LDLRAP1,CTNS,RAB11FIP2,GRIN2D,ITGAV,GPER1,FZD5,WDR45B,CYBRD1,OCLN,CASP3,EPHA4,HDAC6,PDGFB,MAP1LC3B,SLC9A3R2,ABCD4,ZFYVE16,EPCAM,RAB15,ENTPD4,TM9SF2,CTNNB1,CDKL5,SLC44A1,DLG1,ABCA2,TRPC1,RAB20,RP2,CTTN,PXMP4,MYRIP,LAMP3,CD55,SYNE3,EZR,RHEB,HPSE,WIPI1,KCNK1,RAB11FIP1,PRKCDBP,PIEZO1,NRGN,RRAGD,STARD3NL,BMF,BVES,PEX6,HLA-F,NCKAP1,CNTNAP2,DHRS3,ANO1,VASP,IGF1R,CA2,KCNN4,OCRL,FCHO1,COL6A1,PRKCI,HLA-C,NPTN,TMEM8A,WNT3A,FAR2,GAD1,SLC12A2,KDELR1,ABCC1,RGMB,SPATA13,SCRIB,C3orf58,STEAP1,EGFR,C18orf8,RASGRP2,EPN3,INSR,TMEM30A,PHLPP2,SH3BP4,RAB31,CTSA,ATP1B3,PLD1,SHROOM2,PROM2,DRD1,SORBS1,NF2,SLC2A8,ERBB2,EMP2,PRR7,ATP6V0B,WDR44,SMO,VAT1,RPN2,STEAP3,ECE1,LMAN1,FAR1,F2R,CLCN3,EVA1A,KREMEN2,OSTM1,AP5M1,ERBB2IP,DAG1,ATP13A2,PTGS2,DUOX1,ATP1A1,RTN4RL1,PTPRJ,PEX2,MAOA,EFNA5,SPTBN5,IRF7,CHMP4B,ABCA1,COPG1,ARFGEF3,MAN2B2,ANXA3,SORT1,GOLIM4,PACSIN2,PINK1,CD63,TAB3,CTSB,LRP4,GABRG2,ITGA2B,FZD6,PARM1,VPS26A,M6PR,TMEM63A,SNX13,ADORA1,MAGEE1,KIAA0319,ZDHHC13,ABCD1,CAMK2G,P2RX4,DLGAP1,SUN2,RAB3B,ADAM17,RHOA,IFITM3,CRB3,PLAUR,LITAF,BBS2,BCL10,HLA-B,MARC1,RAP2C,ARRB1,PKD2,ATP6V1C1,NDFIP1,L1CAM,ARHGEF4 |
| 4.179e-10 | -21.60 | generation of neurons | biological process | GO:0048699 | 1584 | 323 | 16441 | 2455 |
SSH1,RET,MCOLN3,GATA3,NRG2,PSME1,PLXNA1,CAMK1D,NCS1,PICK1,GRM5,CALM2,TP73,WEE1,PSMD1,DNM2,SEMA3G,PACSIN1,ZBTB18,TIAM1,TFAP2C,ULK2,ARF4,PLCG1,AREG,LIMK1,PLK2,NKD1,UNC5B,ITPKA,ARF6,LZTS1,SEMA6B,SCN5A,CDKN1C,SOX9,SLC1A3,CALR,RAC2,ITGA3,FRY,FLRT3,MEGF8,PRKG1,SORL1,TNFRSF12A,CACNA1D,NCAM1,DGKG,RIMS2,MMD,CALM1,KIF20B,EPHA1,ILK,DPYSL4,NFIB,PSMA4,STX3,RHOB,RASA1,PTPRF,SEMA4D,HTT,MATN2,CLMN,AURKA,NR4A2,EFNA1,B4GAT1,GDF11,ARPC2,NDE1,TRPC3,RPS6KA3,EHD1,SPRED1,FOXO6,IQGAP1,RPS6KA1,CDH1,DACT1,DAB2IP,EPHB4,ACSL4,RASGEF1A,DLG3,ETV4,SEMA3B,SSH3,CAMSAP3,COL6A2,FZD4,SLC11A2,PRKCQ,ALCAM,FZD7,NFIX,EPHA10,IRS2,FYN,JAK1,AXL,SLC9A6,SIPA1L1,RAB29,NRG1,RGS14,COBL,CTHRC1,FARP1,SDC4,FLOT1,PBX3,PLPPR4,SPR,FGF19,EFNB1,SIX4,TEAD3,RND1,NEO1,ANK1,IGSF9,PTEN,KNDC1,BAX,ATP8B1,ERBB3,ERCC2,GFI1,ITM2C,S100A6,FARP2,RASGRF1,TGIF1,B3GNT2,ARHGEF28,FMN1,RAPGEF2,GRIN1,YES1,ABLIM2,CDK5RAP1,CNTNAP1,PITX2,PROM1,FGFR2,NR4A3,RYK,GRIN2D,GPER1,ITGAV,FZD5,ARSB,SHOX2,FOXA1,RGMA,MYL9,CASP3,EMX1,UGT8,AGRN,EPHA4,CUL4B,ARFGEF1,DNER,PDGFB,CACNB4,TMC1,SPTB,PLS3,RPS6KA2,CTNNB1,CDKL5,SHC3,DPYSL2,IL6ST,PSMC2,DLG1,TRPC1,DUSP10,NTN4,MYH14,CTTN,BTBD3,RASGRP1,ATL1,SOD1,MARK1,CELSR2,RNF165,EZR,KLK6,CDK1,RHEB,DPYSL3,IRX3,HS6ST1,GPRC5B,MAP2,PSMC1,MYL12B,GRN,USH1C,RUNX2,SERPINE2,RASA2,ETV5,PSMD7,CALM3,RACGAP1,CNTNAP2,DUSP5,BMP2,RB1,SPP1,VASP,IGF1R,LRRN2,GATA2,KIF13B,PAK2,COL6A1,PRKCI,NPTN,NTN1,WNT3A,PSMA5,CCDC88A,DPYSL5,RGMB,HMG20B,TCF7,SCRIB,RANBP9,CDK5R1,EGFR,CSF1,TMEM30A,PITPNA,SEMA3A,JAK3,KLF7,DRD1,PAX6,NF2,PSME2,TP53,ERBB2,RASGRP3,MICALL2,PHLDA1,PER2,PDGFA,ARTN,LMO4,FRYL,LHX6,BCL6,SMO,TWIST1,DIXDC1,NOTCH3,FRS3,TIMP2,AKT1,CDC20,MYL12A,DAG1,ARHGAP35,RTN4RL1,BHLHB9,PTK7,PSMD3,PEX2,SPTBN5,EFNA5,PLXND1,LIFR,POMGNT2,CTDSP1,BIN1,COL9A3,ADGRG1,ARHGEF11,ARHGEF7,CIT,LRP4,PSMD10,TGFBR1,COL4A5,JAG2,CRABP2,PPP2R3A,NRP2,ITGA2B,GBX2,HDAC9,KIF5B,CDK16,MYCL,BMP7,KIAA0319,SGK1,RPGR,TLE6,CAMK2G,FAM134C,HES1,RHOA,PSMB4,WNT10B,ASPM,STMN3,RUNX3,MAP1B,FAT4,FGF18,PGRMC1,SOX8,L1CAM,NGEF |
| 4.365e-10 | -21.55 | negative regulation of cell communication | biological process | GO:0010648 | 1144 | 246 | 16441 | 2455 |
SIGIRR,LTBP1,TNK1,ACVR1,LGR4,GRIK2,GATA3,NDRG2,PSME1,SYTL4,KIF26A,PICK1,GRM5,SH3KBP1,TP73,PSMD1,RGS12,TGFBR3,CTNNB1,IL6ST,CABP1,RGS3,TSPAN6,PSMC2,DLG1,DNM2,DUSP10,RGS5,CRY2,PPP1CA,CTTN,PTPRE,TNIP1,ACVR1C,ASXL1,ITCH,PBK,SLC35C1,EZR,TNFAIP8L1,SLC25A5,PNKD,OPTN,CXXC4,ENPP1,GRID2IP,ANKRD6,PLK2,TRAF3IP1,MADD,NKD1,RAB11FIP1,NOD2,PRKCDBP,HDAC1,CTNND1,SPRY4,UNC5B,HSPB1,F2RL1,PSMC1,LZTS1,PRKAA2,RUNX2,ARAP3,BMF,SERPINE2,LGALS3,NUAK1,ITGA6,UBASH3B,RASA2,SOX9,PRKAA1,PSMD7,ZNRF3,PHLPP1,FBLN1,DHRS3,DUSP5,LMNA,MECOM,BMP2,CALR,RB1,ITGA3,IGF1R,PIK3AP1,GATA2,PFKL,VASN,DAPK1,FNIP1,SORL1,MAPK7,WNT3A,PSMA5,GPR161,MDFI,SOCS5,CYP26B1,QSOX1,AMER1,STRADB,NPHP3,PSMA4,RANBP9,EGFR,G2E3,PLIN5,RASA1,TSC1,ONECUT1,HTT,NFKBIA,ITPR1,SH3BP4,PIAS2,NLRC5,EGFL7,NR4A2,TOB1,IFI6,XDH,DRD1,SPRED1,NF2,NLRX1,FOXM1,LFNG,INPP5D,DDIT4L,PSME2,RGS20,TP53,SOD2,P2RX7,BCL2L1,PRKACA,APC2,CYP26A1,ZFYVE9,EPM2A,IER3,CCND1,CD46,NOV,DACT1,BCL6,TAX1BP3,DAB2IP,TWIST1,LGMN,CDKN2D,TMBIM1,DVL2,CHP1,SULF2,CTH,SIRT1,PPIF,TIMP2,AKT1,KREMEN2,FIGNL1,PRKCQ,ERBB2IP,CBL,DUSP4,C3orf33,DAG1,ARHGAP35,SOCS3,PTGS2,PTPRJ,FYN,PSMD3,WFS1,STK38,WWTR1,STAT1,TLE1,TRABD2A,PPP1CB,CHMP4B,NRG1,RGS14,ZC3HC1,GCLM,CTHRC1,PINK1,NKX3-1,ARHGEF7,LRP4,PSMD10,TGFBR1,AES,PLD2,NOTUM,GSTP1,ICAM1,HMGXB4,PPP2R3A,FZD6,CD109,CTNNBIP1,SNX13,CARD8,ADORA1,ADRBK1,PTEN,BMP7,GPC3,BAX,TMBIM6,KANK2,ERBB3,FAIM,MAP3K7,SPRY2,DUSP1,TGIF1,ADAM17,RHOA,PSMB4,PLAUR,GCLC,LITAF,PRICKLE1,STMN3,CARD19,PIM3,PELI3,MAPK8IP1,LEMD2,CNOT2,ARHGAP24,RGS9,BANK1,TWSG1,SCG2,TBX18,ARRB1,ITGAV,GPER1,HIPK3 |
| 4.579e-10 | -21.50 | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | MSigDB lists | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | 145 | 51 | 17758 | 2588 |
CCNE2,TXN,DLGAP5,HJURP,FOXM1,CENPI,PTTG1,NDC80,CDCA3,CDCA8,RACGAP1,KIF2C,CCNB1,STIL,CENPN,TOP2A,APOBEC3B,CCNA2,KIF14,PRC1,NEK2,BUB1,RNASEH2A,CKS2,HMMR,PLK1,ZWINT,CENPA,KIF20A,ASPM,ITCH,CDC20,MYBL2,NUSAP1,AURKB,PKMYT1,KIF11,H2AFV,CDK1,FAM64A,E2F1,AURKA,DONSON,KPNA2,CENPE,NCAPG2,CCNB2,UBE2C,E2F8,ESPL1,MELK |
| 4.645e-10 | -21.49 | kidney-Wilms_tumour | COSMIC cancer mutations | kidney-Wilms_tumour | 561 | 136 | 17775 | 2585 |
TNK1,KIAA1462,ACVR1,PPM1J,CAMKK1,EPHA4,RET,CAMK1D,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,STK35,PLK1,NEK4,MARK1,ACVR1C,ASXL1,PBK,ROR1,AURKB,IDH1,SLC25A5,ADRBK2,STK17B,ULK2,CXXC4,PLCH1,PLK2,LIMK1,MYLK,MAP3K11,MAPK13,RNASEL,PRKAA2,CDK17,PRKAA1,ADCK5,NOTCH2,MERTK,BMP2K,RB1,ZNF432,IGF1R,NEK2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,PHKG2,ADCK3,TESK1,AMER1,STRADB,WHSC1,EIF2AK1,PDK3,PDIK1L,EGFR,STK17A,MAPKAPK2,INSR,ALPK3,AURKA,CDK18,MAP3K5,PER3,JAK3,NRBP1,RPS6KA3,DMPK,RPS6KA1,TP53,TESK2,ERBB2,GRK6,PRKACA,DDR1,FLT3,CDK14,SS18,CDH1,PLK4,EPHB4,SCYL3,MAP3K3,AKT1,RIPK2,PTGER4,PRKCQ,PKMYT1,MAP3K6,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,PRKAR1A,MAPK12,TAOK2,DYRK3,PINK1,TGFBR1,PKN1,TRIB2,RND1,ADRBK1,IRAK1,PTEN,CDK16,SGK3,SGK1,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,CASK,YES1,TXK,FGFR2,ACVRL1,HIPK3,MELK |
| 4.728e-10 | -21.47 | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | MSigDB lists | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | 267 | 78 | 17758 | 2588 |
ARMCX3,ST14,NRG2,RHPN2,SDC1,PHLDA1,FAM46C,EPDR1,EPCAM,P4HB,TACC2,RGS3,IL6ST,SLC46A1,RAB20,MANF,LMAN1,PDIA6,EAF2,MCFD2,C15orf39,MYOM1,IRS2,AMZ2,ENPP1,RBM47,WIPI1,NGFRAP1,SHROOM3,ANKRD6,WFS1,TANC2,ABCA1,MAMDC2,DENND5B,HSP90B1,TSPAN15,PDIA3,CTSZ,NCKAP1,SLC1A3,PDIA4,RABGGTA,SYDE2,FOXP2,B3GALNT1,IGF1R,SLC16A6,KCNN4,RRBP1,UBE2J1,TPST1,ECI2,PLEKHF1,ALDH7A1,TSPAN13,CITED2,CKAP4,KDELR1,ABCC1,FARP2,FADS2,IFITM3,GUSB,OXR1,GYLTL1B,PRICKLE1,FNDC3A,BBS2,TXNDC11,ANTXR1,RHOB,SPINT2,MATN2,UACA,CDK18,SH3BGRL2,TMEM173 |
| 4.981e-10 | -21.42 | cell morphogenesis involved in differentiation | biological process | GO:0000904 | 857 | 194 | 16441 | 2455 |
MYL9,CASP3,AGRN,EPHA4,GATA3,NRG2,PSME1,PLXNA1,CACNB4,FAM101B,PDGFB,SPTB,CALM2,RPS6KA2,PSMD1,TGFBR3,CTNNB1,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,MYH14,BTBD3,TIAM1,RASGRP1,ATL1,SOD1,CELSR2,CASP9,RNF165,EZR,LOXL2,ARHGEF26,ULK2,DPYSL3,PLCG1,MAP2,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,BVES,RASA2,SOX9,PSMD7,CALM3,SLC1A3,MERTK,DUSP5,BMP2,RB1,RAC2,VASP,IGF1R,LRRN2,FLRT3,COL6A1,PAK2,CACNA1D,NTN1,WNT3A,NCAM1,PSMA5,EPB41L5,DPYSL5,RGMB,CALM1,SCRIB,EPHA1,ILK,ANTXR1,DPYSL4,RANBP9,NFIB,PSMA4,EGFR,RASA1,CDK5R1,RHOB,SEMA4D,MATN2,FAM83D,PITPNA,NR4A2,EFNA1,B4GAT1,AKIP1,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,KLF7,SPRED1,GRHL2,ST14,PSME2,RPS6KA1,COL18A1,ERBB2,RASGRP3,MICALL2,PDGFA,ARTN,KIF14,DACT1,SMO,DAB2IP,EPHB4,DLG3,RASGEF1A,ETV4,FRS3,SEMA3B,COL6A2,FZD4,S100A4,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,FZD7,ARHGAP35,IRS2,EPHA10,FYN,JAK1,SLC9A6,AXL,PSMD3,SPTBN5,NRG1,EFNA5,PLXND1,COBL,COL9A3,FARP1,ARHGEF11,ARHGEF7,FRMD6,LRP4,FLOT1,PSMD10,TGFBR1,COL4A5,PLPPR4,SPR,FGF19,EFNB1,ITGA2B,NRP2,RND1,NEO1,GBX2,KIF5B,ANK1,PTEN,BMP7,ADAM15,ERBB3,S100A6,CAMK2G,FARP2,RASGRF1,HES1,ARHGEF28,B3GNT2,RHOA,PSMB4,FMN1,RAPGEF2,VAMP3,GRIN1,C1GALT1C1,YES1,ABLIM2,MAP1B,CNTNAP1,FGFR2,SPINT2,FGF18,RYK,NR4A3,PGRMC1,GRIN2D,ITGAV,PLOD3,L1CAM,NGEF,RGMA |
| 5.269e-10 | -21.36 | Wilms_tumour | COSMIC cancer mutations | Wilms_tumour | 562 | 136 | 17775 | 2585 |
TNK1,KIAA1462,ACVR1,PPM1J,CAMKK1,EPHA4,RET,CAMK1D,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,STK35,PLK1,NEK4,MARK1,ACVR1C,ASXL1,PBK,ROR1,AURKB,IDH1,SLC25A5,ADRBK2,STK17B,ULK2,CXXC4,PLCH1,PLK2,LIMK1,MYLK,MAP3K11,MAPK13,RNASEL,PRKAA2,CDK17,PRKAA1,ADCK5,NOTCH2,MERTK,BMP2K,RB1,ZNF432,IGF1R,NEK2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,PHKG2,ADCK3,TESK1,AMER1,STRADB,WHSC1,EIF2AK1,PDK3,PDIK1L,EGFR,STK17A,MAPKAPK2,INSR,ALPK3,AURKA,CDK18,MAP3K5,PER3,JAK3,NRBP1,RPS6KA3,DMPK,RPS6KA1,TP53,TESK2,ERBB2,GRK6,PRKACA,DDR1,FLT3,CDK14,SS18,CDH1,PLK4,EPHB4,SCYL3,MAP3K3,AKT1,RIPK2,PTGER4,PRKCQ,PKMYT1,MAP3K6,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,PRKAR1A,MAPK12,TAOK2,DYRK3,PINK1,TGFBR1,PKN1,TRIB2,RND1,ADRBK1,IRAK1,PTEN,CDK16,SGK3,SGK1,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,CASK,YES1,TXK,FGFR2,ACVRL1,HIPK3,MELK |
| 5.743e-10 | -21.28 | PEREZ_TP63_TARGETS | MSigDB lists | PEREZ_TP63_TARGETS | 326 | 90 | 17758 | 2588 |
NDRG1,TSC22D3,EPHA4,RET,COL18A1,MICALL2,APC2,FAM46C,SLC35E4,CHST2,MXD1,PAK6,SUSD2,SIPA1L2,FRYL,DOK4,REEP1,CNNM4,TNPO2,EPB41L4B,NOTCH3,RASGRP1,LAMP3,MX1,TAF5,TRIM8,ACVR1C,SLC39A8,SYNE2,RHEB,SOCS3,PGF,HS6ST1,PTPRJ,RAB11FIP1,OVOL1,TLE1,UNC5B,HSPB1,ST3GAL1,PCSK5,HS6ST3,COL9A3,TNRC6C,CDKN1C,SLC16A14,NUAK1,ZCCHC24,BIK,GMCL1,ZNRF3,SEPP1,DHRS3,RBP7,PGAP1,TMEM63A,IL17RB,BMP2,IGF1R,FRY,VASN,C10orf54,MOXD1,NTN1,ULBP2,MYLIP,EPB41L5,KCNJ12,LONRF3,TACC1,TCFL5,SPATA13,ZKSCAN2,RUNX3,RAB3IP,IFIT3,GRTP1,DPYSL4,TP53INP2,GNA11,RHOB,CRISPLD2,RASGRP2,CACHD1,INSR,SEMA4D,FGF18,DGAT2,ARRB1,SOX8 |
| 5.747e-10 | -21.28 | positive regulation of protein kinase activity | biological process | GO:0045860 | 596 | 145 | 16441 | 2455 |
CCNC,TXN,CAMKK1,EPHA4,NRG2,PSME1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,PAK6,PSMD1,SHC3,PSMC2,PIK3CA,DLG1,RASGRP1,NEK4,SOD1,PRKAR2B,CDK1,PLCG1,GPRC5B,MADD,NOD2,MAP3K11,CAB39,PSMC1,GAB1,RASA2,PRKAA1,PSMD7,CALM3,DUSP5,BMP2,CYR61,PAK2,MAP3K9,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,MMD,MAPKAPK3,CALM1,STRADB,PDE5A,ILK,PSMA4,EGFR,CDK5R1,RASA1,MAPKAPK2,PRKAG2,INSR,CSF1,STK39,EFNA1,MAP3K5,JAK3,SPRED1,AVPI1,IQGAP1,PSME2,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,EMP2,STIL,FLT3,PDGFA,CCND1,RALB,KIF14,DAB2IP,RASGEF1A,F2R,HSPA2,DVL2,FRS3,MAP3K3,SIRT1,PSRC1,AKT1,RIPK2,FZD4,CD40,MAP3K6,IRS2,FYN,JAK1,STK26,PSMD3,KIAA1804,SLC27A1,NRG1,SPTBN5,EFNA5,PRKAR1A,TAOK2,NKX3-1,PINK1,TAB3,TRAF2,SDC4,PSMD10,TGFBR1,PKN1,FGF19,PDCD10,IRAK1,ADORA1,BAX,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,GRIN1,RGCC,FGFR2,FGF18,ARRB1,PKD2,GRIN2D,PPP2R3C,CENPE,FZD5,CD81 |
| 5.831e-10 | -21.26 | regulation of small GTPase mediated signal transduction | biological process | GO:0051056 | 281 | 82 | 16441 | 2455 |
ARHGAP11A,PLEKHG3,TNK1,FOXM1,TRIP10,RALBP1,ARFGEF1,ERBB2,ARHGEF16,EPS8L2,ARHGEF10L,SIPA1L2,ARHGEF37,KIF14,BCL6,DNM2,DAB2IP,RASGEF1A,TIAM1,F2R,RASGRP1,TIMP2,ARHGDIB,ICMT,ABR,ARHGEF26,ARHGAP35,PLEKHG6,ARHGEF19,MADD,SIPA1L1,PLEKHG1,NRG1,ARF6,ARHGAP4,STARD13,F2RL1,RAP1GAP,ABCA1,FGD1,ARFGEF3,ARHGEF3,ARAP3,FARP1,ADGRG1,ARHGEF11,RASA2,ARHGEF7,FLOT1,RACGAP1,NOTCH2,ARHGEF40,SSX2IP,SYDE2,RAC2,PDCD10,ITGA3,RALGPS2,OCRL,MCF2L,FAM13B,SPRY2,ALS2CL,FARP2,RASGRF1,RHOA,ARHGEF28,ARAP2,SPATA13,STMN3,FBXO8,RHOB,RASA1,ARHGAP24,CSF1,ARAP1,FGD6,RHOBTB2,ARRB1,ARHGEF9,ARHGEF4,NGEF |
| 5.936e-10 | -21.24 | regulation of biological quality | biological process | GO:0065008 | 3288 | 605 | 16441 | 2455 |
DOC2A,TRIM24,ADD1,IBTK,GRIK2,PNPLA2,HEXB,RET,XIAP,ISOC2,BAIAP3,SYTL4,BARD1,KIF26A,GRM5,TP73,CALM2,WEE1,NAPG,PQLC2,PSMD1,TGFBR3,MUC4,ALDH1A3,SLC46A1,RDH14,ATP13A3,DNM2,CLDN4,CRY2,SEMA3G,PIK3CD,ACOX2,TIPARP,CPE,ERAP2,TUBA4A,VPS11,TNIP1,DSTN,KDELR3,PRKAR2B,F12,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,GRID2IP,LIMK1,ATP7B,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,ARF6,HSPB1,SCN5A,NFKBIE,ITGA6,SOX9,MTL5,MERTK,TFAP4,RAC2,MEGF8,RIMS3,FLRT3,FBXO7,CNGA1,DGKG,MYLIP,NUP85,SLC37A1,ERO1A,PLS1,NPHP3,ILK,TP53INP2,GNA11,PSMA4,SFXN5,RHOB,DCP2,PLIN5,IL1R1,SLC4A4,HTT,SEMA4D,ITPR1,DGAT2,AURKA,STK39,ARPC2,CFAP20,CBX5,TRPC3,NUP58,XDH,ADAMTS16,EGLN1,DOCK9,DMPK,MTM1,CCDC109B,PAPSS2,INPP5D,WDTC1,PKP2,PRKACA,CCND1,SCNN1A,SP100,DACT1,MYT1,SCN3A,ENPP4,SSH3,FZD4,SYNE2,SYP,RAB38,IRS2,SHROOM3,WFS1,SLC9A6,AXL,SIPA1L1,INPP4B,PRIMA1,RGS14,TAOK2,HSP90B1,RBM24,HABP4,PDIA3,CTSZ,ANO9,PKN1,ZNF219,GSTP1,SRPX2,ICAM1,PDIA4,SGPL1,NEO1,CTNNBIP1,PDCD10,IGSF9,KCNK5,FDXR,BAX,TMBIM6,MAPK11,AK3,RAG1,TPCN1,TMX1,CRTAP,HCN3,LCA5,PLSCR1,FMN1,RAPGEF2,PIK3R1,EIF5A2,GRIN1,LDLRAP1,PROM1,RAB11FIP2,NR1D2,ACVRL1,SYT7,DBI,NR4A3,ITGAV,CENPE,NUP37,CD81,USF2,FOXA1,CYBRD1,MYL9,AGRN,EPAS1,ARFGEF1,F11R,NENF,ITPR2,HDAC6,PDGFB,SLC9A3R2,SPTB,PCNA,NUP210,RPS6KA2,CTNNB1,P4HB,PSMC2,ABCA2,TLN2,ANO4,NEB,S100A13,PLK1,THRB,CD55,CELSR2,NFE2L1,EZR,ERP44,KLK6,VCP,TRIM9,KCNMB4,KPNA2,PIEZO1,TC2N,MYL12B,MAFF,PRKAA2,USH1C,PSMD7,RACGAP1,NCKAP1,DOCK11,DHRS3,FBLN1,ANO1,B4GALNT1,BMP2,RB1,VASP,TIMP1,GATA2,NTN1,WNT3A,PSMA5,CYP26B1,SCRIB,EIF2AK1,PDK3,CDK5R1,RASGRP2,MAPKAPK2,ITGA7,CSF1,ATP1B3,CCNB2,SEMA3A,NF2,TMX4,DGKA,TP53,P2RX7,EMP2,BCAP31,CYP26A1,SYTL2,IER3,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,TMEM64,SCN2A,LMAN1,GM2A,SIRT1,PPIF,CLCN3,AKT1,CCSAP,CDC20,ACO1,MYL12A,DAG1,ATP13A2,DNAJC10,DUOX1,PTGS2,PTPRJ,IDE,ATP1A1,ABHD12,PSMD3,MAOA,CHMP4B,EFNA5,SYT13,AIFM3,PINK1,DYRK3,CD63,GABRG2,SELL,PSMD10,CRABP2,SIRPA,SLC9A2,FZD6,CDK16,SGK1,TRIM21,CPLX1,SYK,CAMK2G,ATP2B1,P2RX4,RHOA,PSMB4,PLAUR,PPARA,BCAR1,TXNDC11,BBS2,RNPEP,DGKE,PRDX4,DDAH1,SERPINA1,E2F1,PPP2R3C,PKD2,ACADM,NDFIP1,LAMP1,SUN1,GAA,TXN,LGR4,SSH1,ATP8A1,KLC2,TAP1,GATA3,PSME1,PLXNA1,SLC9A7,PICK1,CYP1A1,SESN3,CTGF,STIM1,ZFP36,IL31RA,PIK3CA,STEAP2,IRF2,ZBTB18,XKR8,LAMP2,ACVR1C,BNIP3L,PIF1,SAV1,LDB2,ULK2,PRIM1,SFXN1,PLK2,EIF4EBP2,SLC31A2,F2RL1,FGD1,SEMA6B,KLF2,SCOC,DHPS,DGKQ,PRKAA1,CALB2,SLC25A27,KIF23,TXNDC9,SLC1A3,APBA1,MECOM,CALR,ITGA3,PRKG1,SORL1,TNFRSF12A,CACNA1D,SYTL3,RIMS2,QSOX1,MFI2,CALM1,ANO6,PYGL,NPC2,ATP8B3,RASA1,STX3,PDE11A,FAS,DGKH,GABRD,SLCO4A1,PLEKHH2,CSNK1G1,SLC4A3,ARAP1,FGD6,IRF1,EHD1,PLA2G4A,KIF3C,SLC2A4,THRA,ATP2C2,FTH1,BCL2L1,DDR1,FLT3,APLP2,NOV,CNNM4,DAB2IP,IFIT1,PDE4D,TSPAN1,FLOT2,SEMA3B,MYO5B,CDKN2AIP,DMTN,CLSTN1,TEP1,PRKCQ,SLC11A2,ATP1B1,ITPR3,ATP10D,FYN,POPDC3,ACAD10,STAT1,TRIOBP,NRG1,PRKAR1A,WASF3,PLSCR4,ATP9A,EPS8,ADGRB2,SIX4,SLC25A36,WWP2,SNTA1,RNF128,PTEN,CD9,SGK3,ATP8B1,ERCC2,CNOT6L,TTPA,RASGRF1,CASK,ALDH2,FURIN,VAMP3,C1GALT1C1,YES1,KIF11,CRTC2,ACADSB,PRDX3,ERAP1,LRRK1,GPER1,SLC25A38,EMX1,CASP3,LTBP1,CRYM,UBE2Q1,VARS2,KIF2C,CACNB4,SLC8B1,SH3KBP1,HTR1D,CDKL5,DPYSL2,SIVA1,DLG1,CAPG,AKR1B1,TRPC1,SUN3,KIF22,RAB20,MYH14,CTTN,SLC39A10,RASGRP1,CYP1B1,SOD1,SYNE3,STRIP2,EDNRA,GPRC5B,KCNK1,IARS2,ADIPOR1,PSMC1,PCSK5,ARAP3,SERPINE2,BVES,PEX6,ETV5,ABCG2,ATP6V1E2,CALM3,QSOX2,SPP1,CA2,KCNN4,NPTN,ACAD8,SLC12A2,GAD1,HP1BP3,KDELR1,MDFI,GYLTL1B,HMG20B,PDE5A,NUBP1,STEAP1,FECH,GNAS,TSC1,INSR,PLPP3,TMEM30A,NFKBIA,CTSA,SHROOM2,JAK3,RARG,DRD1,PAX6,PSME2,PDIA5,SOD2,CYP4F11,SMO,STEAP3,GOT1,ECE1,PDIA6,F2R,CHP1,SOAT1,BAG4,CD40,TMTC2,ARHGAP35,ALDH5A1,BHLHB9,PEX2,PTBP3,SPTBN5,PLXND1,ABCA1,GCLM,FBLIM1,POC1B,SERPINB9,LRP4,ITGA2B,XPR1,KIF5B,ADRBK1,ADORA1,ACTA2,IQGAP3,MYO5A,SUN2,RAB3B,WNT10B,GCLC,ASPM,RC3H2,TTC7A,POLD3,MAP1B,SWAP70,PRCP,DHRS2,ARRB1,MCUR1,ATP6V1C1,PLOD3,SOX8,L1CAM,ABCG1,SNPH |
| 6.017e-10 | -21.23 | lung-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | lung-carcinoma-undifferentiated_carcinoma | 1433 | 290 | 17775 | 2585 |
ACVR1,TRIM24,RET,XIAP,NRG2,CARD10,GRM5,PAK6,WEE1,FOSB,PIK3CA,PPP1CA,PIK3CD,TFG,TIAM1,TIPARP,ACVR1C,CASP9,PRKAR2B,AURKB,SAV1,PPP1R14C,CCNF,LCP1,PIAS3,PLCG1,TRIM47,AREG,PPP2R4,MAP3K11,HDAC1,MAPK13,SPRY4,TRAF5,HSPB1,GAB1,HOXC13,INPPL1,PRKAA1,RAB23,NOTCH2,MERTK,PSIP1,MECOM,RAC2,ZNRF2,CD22,NEK2,MSH2,USP1,USP38,MAPK7,SOCS5,DDB2,STAT4,AMER1,SHARPIN,CALCRL,WHSC1,ELK1,FBXO10,RHOB,RASA1,FAS,IL1R1,PRKAG2,ETS2,ITPR1,PIAS2,AURKA,NDE1,MAP3K5,RPS6KA3,PLA2G4A,ELK4,SPRED1,LFNG,IQGAP1,SUZ12,RALBP1,RNF182,BCL2L1,PRKACA,FLT3,DDR1,KTN1,REPS1,CD46,CCND1,CCNA2,MUC16,CDH1,RALB,CDKN1B,EPHB4,RNASEH2A,ETV4,FLOT2,FZD4,SEPT6,CLSTN1,PRKCQ,PKMYT1,CBL,ITPR3,FZD7,EPHA10,IRS2,FYN,PPP2R5A,JAK1,AXL,STAT1,PPP1CB,NRG1,ARNT,MAPK12,PRKAR1A,OTUD5,IGFBP6,PARP14,TRAF2,HERC5,PKN1,ETS1,FGF19,PDIA4,WWP2,CAPN2,DIRAS3,DTX3L,PDCD10,IRAK1,PTEN,GPC3,SGK3,BAX,ATP8B1,WWP1,MAPK11,IGFBP2,ERCC2,ERBB3,MAP3K7,SPRY2,NCOA2,MSH6,PARP9,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,UBE2A,FURIN,FOS,CNTNAP1,BTG1,FGFR2,CCDC6,RIN3,PPM1H,FZD5,USP16,CASP3,PPM1J,EPHA4,PDGFB,DNER,KREMEN1,RPS6KA2,CTNNB1,CNTRL,MKRN3,MITF,DUSP10,TLN2,PLK1,CELSR2,USP18,ITCH,ROR1,ADRBK2,RHEB,EDNRA,NEIL1,GPRC5B,HOXA9,PIK3C2B,PPP2R5D,PRKAA2,LASP1,PARP12,RASA2,ETV5,PSMD7,DUSP5,BMP2,OTUD1,RB1,IGF1R,PRKCI,PIM1,ZRANB1,ELK3,USP31,KBTBD8,STEAP1,EGFR,G2E3,GNAS,MAPKAPK2,TSC1,INSR,OTUD6B,NFKBIA,EGFL7,YOD1,PLD1,JAK3,RARG,USP43,LMO7,PAX6,NF2,TP53,ERBB2,MRAS,RASGRP3,CCNL1,STIL,EXT2,PDGFA,SS18,PLCG2,BCL6,SMO,GYS1,CDH3,TWIST1,NOTCH3,NFKB2,DVL2,MAP3K3,AKT1,KREMEN2,PTGER4,DUSP4,CD40,FANCE,CDC25C,CASP4,MAP3K6,SOCS3,STAT6,STK38,PTK7,LIFR,ABCA1,FRMD6,TGFBR1,JAG2,FZD6,PPP2R3A,KIF5B,MYCL,SGK1,BUB1,SYK,DUSP1,HES1,RHOA,ADAM17,WNT10B,AMFR,RC3H2,MAML2,BCAR1,MAPK8IP1,BCL10,USP6,CASP7,RND3,NEIL3,FGF18,RAP2C,DTX4,ARRB1,OTUB2,GEM |
| 6.073e-10 | -21.22 | liver-carcinoma | COSMIC cancer mutations | liver-carcinoma | 16152 | 2428 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,IL10RB,CPE,CCDC74A,NEK4,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,TRIQK,POPDC3,ACAD10,NGFRAP1,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,ARHGEF3,PCOLCE,SLC16A14,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,NPM2,CDKN2C,NAPG,MUC4,CRY2,TMEM37,WBP4,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,ATP5H,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,AIP,LBR,PARM1,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,TMEM221,FBXO9,YES1,GRTP1,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,PSMC1,MIIP,GRN,ELOVL7,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,TADA2B,UBE2D2,GEM |
| 6.083e-10 | -21.22 | SMID_BREAST_CANCER_BASAL_DN | MSigDB lists | SMID_BREAST_CANCER_BASAL_DN | 653 | 153 | 17758 | 2588 |
SIGIRR,ACACB,BCAM,HEBP1,ATP8A1,PNPLA2,RET,CACNA2D2,CCNO,GATA3,BAIAP3,PLA2G16,TRIM68,LRRC6,IL6ST,FOSB,AOX1,TMEM143,ATRNL1,RGS5,CRY2,SEMA3G,ACOX2,CPE,SH3BGRL,STAU2,NKAIN1,GALNT7,SEC14L2,CXXC4,ENPP1,MSL1,RBM47,AREG,ATP7B,LRIG1,RAB11FIP1,SERPINI1,TTC9,TRAF5,HSPB1,PCSK5,ZCCHC24,MTL5,ASAH1,ISYNA1,CNTNAP2,FBLN1,ANO1,DUSP5,IGF1R,FRY,RALGPS2,GATA2,SLC16A6,FLRT3,KIF13B,SORL1,CACNA1D,MAST4,KCTD3,MCCC2,SNED1,PRSS23,SPTLC2,MFSD7,CYB5A,RHOB,MAGED2,NCOA3,TJP3,FAAH,ITGA7,ITPR1,C1orf21,TCEAL4,NR4A2,STK39,TOB1,NQO1,REPS2,SLC2A8,HDAC11,C5orf30,ERBB2,ZMYND10,EGR3,FAM198B,APPBP2,SYTL2,CYP26A1,CDS1,CCND1,SCNN1A,REEP1,DLG3,TSPAN1,RAB27B,MYT1,HSPA2,SEMA3B,CPD,SSH3,KIAA0040,LGALS8,C3orf52,RAB38,DUSP4,ALCAM,ARHGAP35,TTC12,MMP17,INPP4B,CANT1,MAOA,ANXA9,FAM134B,BIK,BLVRB,CYB561,GDF15,COL4A5,NUCB2,SEPP1,HOXB2,RND1,MDM1,MLPH,GPC3,MCF2L,FUT8,CST3,FDXR,TRIM3,TSPAN13,WWP1,ERBB3,CASD1,FAH,DENND1B,CRIP2,SYBU,BLVRA,NPDC1,DCAF10,ACADSB,DHRS2,NAT1,TMC5,FOXA1,CYBRD1,SNPH,ABCG1 |
| 6.323e-10 | -21.18 | WHITEFORD_PEDIATRIC_CANCER_MARKERS | MSigDB lists | WHITEFORD_PEDIATRIC_CANCER_MARKERS | 113 | 43 | 17758 | 2588 |
DLGAP5,CKAP2,PTTG1,CDCA8,NUF2,CCNB1,CENPN,TOP2A,PCNA,CCNA2,KIF14,PRC1,PLK4,NEK2,CKS1B,TWIST1,BUB1,RNASEH2A,SMC4,CKS2,ZWINT,CENPA,PBK,MYBL2,CCDC34,WHSC1,NUSAP1,GGH,CDCA2,KIF11,CDK1,PAFAH1B3,ZNF367,SLC25A40,CDCA5,E2F1,AURKA,KPNA2,CENPE,CCNB2,UBE2C,ESPL1,MELK |
| 6.459e-10 | -21.16 | KIM_WT1_TARGETS_DN | MSigDB lists | KIM_WT1_TARGETS_DN | 427 | 110 | 17758 | 2588 |
GAS2L1,PLA2G4A,DLGAP5,LGR4,TRIM5,XYLT1,NDC80,SOD2,KIF2C,BCL2L1,BARD1,MNS1,MOCS1,SDF4,APPBP2,CCND1,ACAP2,CCNA2,DPYSL2,KIF14,LMO4,ANKRD12,CDKN1B,IRF2,KIF22,IFIT1,MANF,TECR,ARMCX6,MYBL1,UPF3A,CKS2,SIRT1,SOAT1,TAF5,PSRC1,CENPA,SNTB2,DRAP1,CDC20,MGAM,HTATIP2,TFAP2C,NUSAP1,AURKB,CCNF,H2AFV,STK17B,CDK1,ATP10D,TRAM2,FASTKD1,ACYP1,WIPI1,PLK2,HOXA9,NRG1,F2RL1,NUDT6,HJURP,CKAP2,NUAK1,CENPI,CDCA3,ARL4C,CDCA8,KIF23,ASAH1,NDUFA4,RACGAP1,GPSM2,RSAD1,SAC3D1,TOP2A,FAM111A,MDM1,BHLHE41,NEK2,BUB1,HSPA13,PIKFYVE,ZMYM1,CITED2,MPHOSPH9,NCOA2,HES1,TGIF1,HMGN5,KIF20A,ASPM,RAPGEF2,KDM3A,KIF11,CDK5R1,NMT2,KLHL2,GNAS,PITX2,FAM64A,DGCR2,PLOD2,FGD6,AURKA,HOXB13,CENPE,PER3,C17orf75,ESPL1,TOB1,RAD21 |
| 6.459e-10 | -21.16 | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | 427 | 110 | 17758 | 2588 |
SUN1,GAA,ACVR1,TCF25,PDIA5,SLC20A1,DDR1,TNFSF9,BCAP31,CHPF,APLP2,PSMD1,CTNNB1,TM9SF2,RGS3,ZFP36,IL6ST,KLF3,FOSB,ABCA2,STEAP3,RPN2,EPHB4,LGMN,PDIA6,NAGA,SEMA3B,TIMP2,TMEM43,CLSTN1,IGSF8,SLC11A2,ESYT1,LHFPL2,DAG1,POR,FZD7,SOCS3,TAPBP,ATP1A1,GPRC5B,DDOST,ABHD12,P4HA2,AXL,BMP1,AGFG2,NFKBIZ,GLA,GRN,CDS2,MPZL1,RUSC2,CTSB,PDIA3,GMCL1,COL4A5,ADAMTSL4,NRP2,SGPL1,WWP2,CD109,GNS,ITGA3,IGF1R,PFKL,KCNN4,CALD1,VASN,SLC30A6,RRBP1,CD9,SLC44A2,NCEH1,MAST4,CKAP4,SNED1,IGSF3,ABCC1,DUSP1,P2RX4,SUN2,QSOX1,TGIF1,PGM1,PCDH1,RGMB,BCL9,C1GALT1C1,TTC7A,TRIM35,PIM3,FOS,TP53INP2,NFIB,PTPRF,BTG1,SLC6A6,RPL12,TIMP3,DGCR2,TWSG1,HTT,MATN2,PCDH19,ARFGAP3,PER3,ZMIZ1,COL16A1,DCBLD1 |
| 6.653e-10 | -21.13 | negative regulation of phosphorylation | biological process | GO:0042326 | 388 | 104 | 16441 | 2455 |
CASP3,SPRED1,NF2,IBTK,FOXM1,DNAJC3,CTDSPL,P2RX7,NDRG2,CCNB1,IER3,TP73,CALM2,CDKN2C,DACT1,RGS3,DLG1,DUSP10,CDKN1B,DAB2IP,TWIST1,PDE4D,CDKN2D,CTDSP2,CHP1,PLK1,PPIF,SIRT1,TNIP1,AKT1,ITCH,DMTN,PBK,COX11,EZR,PRKAR2B,DUSP4,C3orf33,DAG1,SOCS3,IRS2,ENPP1,DNAJC10,PTPRJ,CAMK2N2,PPP2R5A,CORO1C,STK38,TRAF3IP1,WWTR1,SPRY4,RGS14,HSPB1,F2RL1,CTDSP1,PRKAR1A,PINK1,CDKN1C,UBASH3B,CALM3,PSMD10,PKN1,TRIB2,GSTP1,FBLN1,DUSP5,MECOM,CD109,TFAP4,RB1,IGF1R,PTEN,BMP7,FBXO7,PAK2,BAX,H2AFY,SORL1,HEXIM2,SPRY2,SOCS5,DUSP1,RHOA,CALM1,PPARA,EPHA1,ILK,RANBP9,MAPK8IP1,LEMD2,CDK5RAP1,PRKAG2,PRDX3,SEMA4D,PLPP3,ARRB1,STK39,GPER1,LRRK1,UBE2C,HIPK3,PKIA,XDH,DRD1 |
| 6.695e-10 | -21.12 | negative regulation of signaling | biological process | GO:0023057 | 1132 | 243 | 16441 | 2455 |
SIGIRR,LTBP1,TNK1,ACVR1,LGR4,GRIK2,GATA3,NDRG2,PSME1,SYTL4,KIF26A,PICK1,GRM5,SH3KBP1,TP73,PSMD1,RGS12,TGFBR3,CTNNB1,IL6ST,RGS3,TSPAN6,PSMC2,DLG1,DNM2,DUSP10,RGS5,CRY2,PPP1CA,CTTN,PTPRE,TNIP1,ACVR1C,ASXL1,ITCH,PBK,SLC35C1,EZR,TNFAIP8L1,SLC25A5,PNKD,OPTN,CXXC4,ENPP1,GRID2IP,ANKRD6,PLK2,TRAF3IP1,MADD,NKD1,RAB11FIP1,NOD2,PRKCDBP,HDAC1,CTNND1,SPRY4,UNC5B,HSPB1,F2RL1,PSMC1,PRKAA2,RUNX2,ARAP3,BMF,SERPINE2,LGALS3,NUAK1,ITGA6,UBASH3B,RASA2,SOX9,PRKAA1,PSMD7,ZNRF3,PHLPP1,FBLN1,DHRS3,DUSP5,LMNA,MECOM,BMP2,CALR,RB1,ITGA3,IGF1R,PIK3AP1,GATA2,PFKL,VASN,DAPK1,FNIP1,SORL1,MAPK7,WNT3A,PSMA5,GPR161,MDFI,SOCS5,CYP26B1,AMER1,STRADB,NPHP3,PSMA4,RANBP9,EGFR,G2E3,PLIN5,RASA1,TSC1,AP1AR,ONECUT1,HTT,NFKBIA,ITPR1,SH3BP4,PIAS2,NLRC5,EGFL7,NR4A2,TOB1,IFI6,XDH,DRD1,SPRED1,NF2,NLRX1,FOXM1,LFNG,INPP5D,DDIT4L,PSME2,RGS20,TP53,SOD2,P2RX7,BCL2L1,PRKACA,APC2,CYP26A1,ZFYVE9,EPM2A,IER3,CCND1,CD46,NOV,DACT1,BCL6,TAX1BP3,DAB2IP,TWIST1,LGMN,CDKN2D,TMBIM1,DVL2,CHP1,SULF2,CTH,SIRT1,PPIF,TIMP2,AKT1,KREMEN2,FIGNL1,PRKCQ,ERBB2IP,CBL,DUSP4,C3orf33,DAG1,ARHGAP35,SOCS3,PTGS2,PTPRJ,FYN,PSMD3,STK38,WFS1,WWTR1,STAT1,TLE1,TRABD2A,PPP1CB,NRG1,RGS14,ZC3HC1,GCLM,CTHRC1,PINK1,NKX3-1,ARHGEF7,LRP4,PSMD10,TGFBR1,AES,PLD2,NOTUM,GSTP1,ICAM1,HMGXB4,PPP2R3A,FZD6,CD109,CTNNBIP1,SNX13,CARD8,ADORA1,ADRBK1,PTEN,BMP7,GPC3,BAX,TMBIM6,KANK2,ERBB3,FAIM,MAP3K7,SPRY2,DUSP1,TGIF1,ADAM17,RHOA,PSMB4,PLAUR,GCLC,LITAF,PRICKLE1,STMN3,CARD19,PIM3,PELI3,MAPK8IP1,LEMD2,CNOT2,ARHGAP24,RGS9,BANK1,TWSG1,SCG2,TBX18,ARRB1,ITGAV,GPER1,HIPK3 |
| 6.929e-10 | -21.09 | negative regulation of protein phosphorylation | biological process | GO:0001933 | 349 | 96 | 16441 | 2455 |
CASP3,SPRED1,NF2,IBTK,FOXM1,DNAJC3,CTDSPL,P2RX7,NDRG2,CCNB1,TP73,CALM2,CDKN2C,DACT1,RGS3,DLG1,DUSP10,CDKN1B,DAB2IP,TWIST1,PDE4D,CDKN2D,CTDSP2,CHP1,PLK1,SIRT1,TNIP1,AKT1,ITCH,DMTN,PBK,EZR,PRKAR2B,DUSP4,C3orf33,DAG1,SOCS3,ENPP1,DNAJC10,PTPRJ,CAMK2N2,CORO1C,STK38,TRAF3IP1,WWTR1,SPRY4,RGS14,HSPB1,F2RL1,CTDSP1,PRKAR1A,PINK1,CDKN1C,UBASH3B,CALM3,PSMD10,PKN1,TRIB2,GSTP1,FBLN1,DUSP5,MECOM,CD109,TFAP4,RB1,IGF1R,PTEN,BMP7,FBXO7,PAK2,BAX,SORL1,H2AFY,HEXIM2,SPRY2,DUSP1,SOCS5,CALM1,EPHA1,ILK,RANBP9,MAPK8IP1,LEMD2,CDK5RAP1,PRKAG2,SEMA4D,PLPP3,ARRB1,STK39,GPER1,LRRK1,UBE2C,HIPK3,PKIA,XDH,DRD1 |
| 7.029e-10 | -21.08 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | 392 | 103 | 17758 | 2588 |
LAMP1,SIGIRR,NQO1,NDRG1,TMX4,APOO,HEXB,SOD2,PDIA5,IL18,FTH1,TEX2,BCAP31,TSEN34,CCND1,ZFYVE16,APLP2,ATP13A3,MITF,AKR1B1,VAT1,RAB20,SNX10,GM2A,TUBA4A,CYP1B1,LAMP2,CPD,DOCK4,PPIF,TIMP2,CD55,MCTP1,ACO1,SLC11A2,LHFPL2,MAN2A2,FYN,MPRIP,FASTKD1,RBM47,STAT1,PDXK,GLA,LTA4H,CHPT1,ST3GAL1,GCLM,CDS2,PACSIN2,PINK1,MPZL1,LGALS3,CDKN1C,ZNF395,CD63,TBC1D1,HLA-E,CTSB,C6orf106,SELL,ASAH1,GTF3A,SLC1A3,NOTCH2,ARHGEF40,HDAC9,GNS,TNS3,SPP1,MDM1,SLC16A6,BHLHE41,TPST1,TMEM51,CD9,SGK1,TMBIM6,KLF9,CTSD,CNPY3,ALDH3A2,FAH,WBP5,SUN2,PLSCR1,GGH,SNTB1,SPTLC2,STK17A,SCARB2,ETS2,NAT1,ITPR1,CCDC69,ARFGAP3,NR4A2,MDH1,LTBP2,ATP6V1C1,PLOD3,CD81,IFI6 |
| 7.182e-10 | -21.05 | Axon guidance | REACTOME pathways | R-HSA-422475 | 516 | 129 | 8202 | 1235 |
MYL9,AGRN,EPHA4,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,PAK6,PSMD1,RPS6KA2,SHC3,DPYSL2,PSMC2,DLG1,DNM2,DUSP10,TRPC1,NTN4,MYH14,TIAM1,RASGRP1,EZR,DPYSL3,PLCG1,LIMK1,MAP3K11,UNC5B,PSMC1,MYL12B,PPP2R5D,SCN5A,RASA2,PSMD7,CALM3,DUSP5,RAC2,VASP,PAK2,COL6A1,CACNA1D,NCAM1,NTN1,PSMA5,DPYSL5,RGMB,CALM1,EPHA1,DPYSL4,PSMA4,RANBP9,RHOB,CDK5R1,RASA1,EGFR,SEMA4D,PITPNA,EFNA1,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,SPRED1,IQGAP1,RPS6KA1,PSME2,ERBB2,RASGRP3,PDGFA,ARTN,DAB2IP,EPHB4,RASGEF1A,DLG3,SCN2A,SCN3A,FRS3,COL6A2,PRKCQ,DUSP4,ALCAM,MYL12A,ARHGAP35,IRS2,EPHA10,FYN,JAK1,PPP2R5A,PSMD3,SPTBN5,NRG1,EFNA5,PLXND1,COL9A3,ARHGEF11,ARHGEF7,PSMD10,COL4A5,EFNB1,FGF19,NRP2,ITGA2B,NEO1,RND1,ANK1,ERBB3,CAMK2G,FARP2,DUSP1,RASGRF1,RHOA,ARHGEF28,PSMB4,RAPGEF2,GRIN1,YES1,ABLIM2,CNTNAP1,FGFR2,FGF18,ARRB1,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 7.382e-10 | -21.03 | GNF2_ESPL1 | MSigDB lists | GNF2_ESPL1 | 35 | 21 | 17758 | 2588 |
HMMR,PLK1,CENPA,KIF20A,FOXM1,ASPM,CDC20,CDCA8,KIF2C,AURKB,KIF11,TOP2A,CCNA2,PCNA,CKS1B,BUB1,CENPE,UBE2C,CCNB2,ESPL1,MELK |
| 7.411e-10 | -21.02 | BILD_HRAS_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_HRAS_ONCOGENIC_SIGNATURE | 241 | 72 | 17758 | 2588 |
GRHL2,NDRG1,EPHA4,CD274,CCNL1,SLC20A1,SDC1,PHLDA1,MAP1LC3B,MXD1,IER3,PDGFA,C7orf49,ST5,ZFP36,BCL6,PIK3CD,PTPRE,TUBA4A,CYP1B1,PPIF,CD55,LGALS8,DUSP4,ITPR3,LHFPL2,COL12A1,TNS4,PTGS2,HPSE,KCNK1,FAM110C,KLF5,NFKBIZ,SPRY4,GLCCI1,ABCA1,TTC8,TMTC3,ELOVL7,SDC4,HMGN3,GDF15,EFNB1,DUSP5,BMP2,TIMP1,KCNN4,FLRT3,TNFRSF12A,PIM1,ULBP2,MAST4,ATP2B1,S100A6,DUSP1,ELK3,PLAUR,FBXO9,FOS,NFIB,UAP1,FGFR2,MFSD2A,SERPINB5,SAMD8,MDH1,SERPINB1,ARHGEF9,TOB1,ACOT7,EHD1 |
| 7.430e-10 | -21.02 | positive regulation of transferase activity | biological process | GO:0051347 | 688 | 162 | 16441 | 2455 |
CCNC,TXN,CAMKK1,EPHA4,CUL1,NRG2,PSME1,CCNB1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,PAK6,PSMD1,CTNNB1,SHC3,PSMC2,SERINC2,PIK3CA,DLG1,RASGRP1,PLK1,NEK4,SOD1,PRKAR2B,AURKB,CDK1,PLCG1,GPRC5B,MADD,NOD2,MAP3K11,CAB39,PSMC1,GAB1,PIFO,RASA2,PRKAA1,PSMD7,CALM3,DUSP5,BMP2,CYR61,PAK2,NEK2,MAP3K9,SORL1,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,MMD,MAPKAPK3,CALM1,STRADB,PDE5A,ILK,PSMA4,EGFR,CDK5R1,RASA1,MAPKAPK2,PRKAG2,INSR,CSF1,DCUN1D1,STK39,EFNA1,MAP3K5,JAK3,SPRED1,AVPI1,GRHL2,IQGAP1,PSME2,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,EMP2,STIL,FLT3,PDGFA,CCND1,RALB,KIF14,DAB2IP,RASGEF1A,F2R,HSPA2,DVL2,FRS3,MAP3K3,SIRT1,PSRC1,AKT1,RIPK2,PFKFB2,FZD4,CDC20,PRKCQ,CD40,MAP3K6,IRS2,FYN,JAK1,STK26,PSMD3,KIAA1804,SLC27A1,NRG1,SPTBN5,EFNA5,PRKAR1A,TAOK2,NKX3-1,PINK1,TAB3,TRAF2,SDC4,PSMD10,TGFBR1,PKN1,FGF19,PARM1,PDCD10,IRAK1,ADORA1,PTEN,BAX,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,GRIN1,RGCC,FGFR2,FGF18,ARRB1,PPP2R3C,PKD2,GRIN2D,CENPE,FZD5,CD81,UBE2C |
| 7.581e-10 | -21.00 | GNF2_TTK | MSigDB lists | GNF2_TTK | 38 | 22 | 17758 | 2588 |
HMMR,ZWINT,HJURP,FOXM1,ASPM,CDC20,NDC80,RACGAP1,NUSAP1,KIF2C,KIF11,CDK1,FANCI,TOP2A,CCNA2,PCNA,PRC1,PLK4,CCNB2,MELK,SMC4,CKS2 |
| 7.828e-10 | -20.97 | neurotrophin TRK receptor signaling pathway | biological process | GO:0048011 | 394 | 105 | 16441 | 2455 |
CASP3,SPRED1,RPS6KA1,PSME2,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,ARHGEF16,PDGFA,CALM2,RPS6KA2,PSMD1,SHC3,RALB,PSMC2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,TIAM1,RASGRP1,FRS3,RIPK2,AKT1,CASP9,PRKAR2B,AGO4,DUSP4,ITPR3,ABR,IRS2,PLCG1,FYN,JAK1,NGFRAP1,PSMD3,HDAC1,MAPK13,SPTBN5,NRG1,ARHGAP4,GAB1,PPP2R5D,PSMC1,PCSK5,FGD1,PRKAR1A,MAPK12,ARHGEF3,TNRC6C,SORT1,ARHGEF11,RASA2,ARHGEF7,PSMD7,PSMD10,CALM3,PHLPP1,DUSP5,FGF19,ADRBK1,IRAK1,PTEN,MCF2L,PRKCI,MAPK11,ERBB3,NCAM1,MAPK7,PSMA5,CAMK2G,RASGRF1,ADAM17,RHOA,PSMB4,MAPKAPK3,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,FURIN,ELK1,BCAR1,PSMA4,EGFR,RASA1,MAPKAPK2,FGFR2,PHLPP2,NFKBIA,ITPR1,FGF18,GRIN2D,JAK3,ARHGEF9,RPS6KA3,ARHGEF4,NGEF |
| 7.872e-10 | -20.96 | DODD_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_UP | 1528 | 306 | 17758 | 2588 |
SUN1,KLK10,TTC39B,AK7,FAM129B,CCNO,IL18,SYTL4,BAIAP3,PHF1,GRM5,AP1M2,CTGF,DNAH6,STIM1,ZFP36,ALDH1A3,PPP1R16A,SERINC2,IQCD,TACSTD2,CRY2,RCAN3,ODF2L,ANKRD9,TUBA4A,ORAI2,SPEF2,VPS11,SPATA18,SERTAD4,CASP9,MGAM,SLC35C1,TNS1,PNKD,SPNS3,POR,PIAS3,HLF,TRAF3IP1,AGFG2,SERPINB6,TMEM8B,WBSCR27,GAB1,ANXA11,KLF2,CDKN1C,TMEM55B,TNFRSF19,CCDC64B,KIAA1161,ELF3,DOPEY2,RALGPS2,CD22,BHLHE41,FLRT3,BDH1,RUNDC3B,MAP3K9,SLAIN2,C9orf72,PPP6R1,DNAI1,PAQR7,REC8,B3GNT7,QSOX1,KCNJ12,SLC37A1,PRSS23,B9D2,PTPRH,FHL2,PYGL,PLS1,SPTLC2,TP53INP2,GNA11,FRMD4B,DHX32,MMP15,MAGED2,NT5C2,TJP3,SETD3,SFMBT1,CLMN,NR4A2,OSCP1,PLIN3,SERPINB1,RPS6KA3,DOCK9,WDR63,NQO1,TCTN2,NLRX1,TUBB4B,ST14,CAST,GALNT12,THRA,ATP2C2,WDTC1,PRSS22,GRK6,MNS1,TMPRSS4,CYP39A1,EPS8L2,CDS1,APLP2,SCNN1A,MUC16,ENPP5,LRP11,TSPAN1,OSBPL7,TMBIM1,MYO5B,ENPP4,SAT1,RAB38,TRIM7,OSBPL2,ALDH3B1,PPP2R5A,TTC12,WFS1,SIPA1L1,KLF5,SLC27A1,FAM149A,RGS14,ARNT,CBX7,COBL,PRR15,PRKAR1A,RBM24,BACE1,EFHD2,CYB561,NUCB2,DNAH3,SRPX2,WWP2,PHF7,SLC27A6,FUT2,MCF2L,KNDC1,FAM102A,TPCN1,SLC16A5,S100A6,FARP2,AMOTL2,PVRL4,LCA5,FMN1,RAPGEF2,MYEOV,DIAPH2,LDLRAP1,PROM1,CTNS,KIAA0141,DGCR2,SEC14L4,RIN3,ABCB1,CCDC69,CSTF2,FHL1,FOXA1,EXPH5,SIGIRR,EPAS1,CRYM,CAMKK1,FHDC1,NDRG2,DNER,RPS6KA2,LRRC6,ARHGEF37,TSPAN6,ANKFN1,MYH14,SCARA3,SMAGP,KRT80,THRB,ATL1,CXXC5,CD55,CR2,EZR,TNFAIP8L1,STK17B,DZIP1L,NEIL1,AGPAT2,RAB11FIP1,PIK3C2B,TTC9,TTC39C,MYL12B,CPPED1,PCSK5,PRKAA2,LGALS3,ZNF395,DNAJB2,ASL,PHLPP1,DHRS3,OTUD1,AIM1L,NOXA1,CES2,KIF13B,C10orf54,ALS2CL,ALDH3A2,SNED1,C9orf9,PLEKHA6,PCDH1,ELK3,PCBP3,SPA17,ZDHHC3,RASGRP2,FECH,EPN3,MOSPD3,SLC6A6,FA2H,COQ10A,SPAG7,RHOBTB2,PITPNA,TMEM120A,USP43,LMO7,LZTFL1,ZSWIM5,SLC25A24,RHPN2,ERBB2,ZMYND10,SYTL2,C1orf116,PER2,TACC2,REEP1,BCL6,DIXDC1,EPB41L4B,CTH,MBP,PTPRU,DUOX1,ANXA9,BTBD6,GCLM,SORT1,PINK1,SH3D19,GNAL,GNE,GDF15,IL22RA1,MLPH,ADORA1,LLGL2,A4GALT,KIAA0319,FAM63A,ZDHHC13,HMGCL,CAMK2G,DUSP1,HES1,AMFR,SYBU,TTC7A,BCAR1,SPAG1,SCRN2,TMEM50B,CASP7,C2orf70,ZNF214,TMC5,TADA2B,DTX4,CLIP4,SH3BGRL2,GRAMD1C,SAT2 |
| 8.215e-10 | -20.92 | undifferentiated_carcinoma | COSMIC cancer mutations | undifferentiated_carcinoma | 1443 | 291 | 17775 | 2585 |
ACVR1,TRIM24,RET,XIAP,NRG2,CARD10,GRM5,PAK6,WEE1,FOSB,PIK3CA,PPP1CA,PIK3CD,TFG,TIAM1,TIPARP,ACVR1C,CASP9,PRKAR2B,AURKB,SAV1,PPP1R14C,CCNF,LCP1,PIAS3,PLCG1,TRIM47,AREG,PPP2R4,MAP3K11,HDAC1,MAPK13,SPRY4,TRAF5,HSPB1,GAB1,HOXC13,INPPL1,PRKAA1,RAB23,NOTCH2,MERTK,PSIP1,MECOM,RAC2,ZNRF2,CD22,NEK2,MSH2,USP1,USP38,MAPK7,SOCS5,DDB2,STAT4,AMER1,SHARPIN,CALCRL,WHSC1,ELK1,FBXO10,RHOB,RASA1,FAS,IL1R1,PRKAG2,ETS2,ITPR1,PIAS2,AURKA,NDE1,MAP3K5,RPS6KA3,PLA2G4A,ELK4,SPRED1,LFNG,IQGAP1,SUZ12,RALBP1,RNF182,BCL2L1,PRKACA,FLT3,DDR1,KTN1,REPS1,CD46,CCND1,CCNA2,MUC16,CDH1,RALB,CDKN1B,EPHB4,RNASEH2A,ETV4,FLOT2,FZD4,SEPT6,CLSTN1,PRKCQ,PKMYT1,CBL,ITPR3,FZD7,EPHA10,IRS2,FYN,PPP2R5A,JAK1,AXL,STAT1,PPP1CB,NRG1,ARNT,MAPK12,PRKAR1A,OTUD5,IGFBP6,PARP14,TRAF2,HERC5,PKN1,ETS1,FGF19,PDIA4,WWP2,CAPN2,DIRAS3,DTX3L,PDCD10,IRAK1,PTEN,GPC3,SGK3,BAX,ATP8B1,WWP1,MAPK11,IGFBP2,ERCC2,ERBB3,MAP3K7,SPRY2,NCOA2,MSH6,PARP9,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,UBE2A,FURIN,FOS,CNTNAP1,BTG1,FGFR2,CCDC6,RIN3,PPM1H,FZD5,USP16,CASP3,PPM1J,EPHA4,PDGFB,DNER,KREMEN1,RPS6KA2,CTNNB1,CNTRL,MKRN3,MITF,DUSP10,TLN2,PLK1,CELSR2,USP18,ITCH,ROR1,IDH1,ADRBK2,RHEB,EDNRA,NEIL1,GPRC5B,HOXA9,PIK3C2B,PPP2R5D,PRKAA2,LASP1,PARP12,RASA2,ETV5,PSMD7,DUSP5,BMP2,OTUD1,RB1,IGF1R,PRKCI,PIM1,ZRANB1,ELK3,USP31,KBTBD8,STEAP1,EGFR,G2E3,GNAS,MAPKAPK2,TSC1,INSR,OTUD6B,NFKBIA,EGFL7,YOD1,PLD1,JAK3,RARG,USP43,LMO7,PAX6,NF2,TP53,ERBB2,MRAS,RASGRP3,CCNL1,STIL,EXT2,PDGFA,SS18,PLCG2,BCL6,SMO,GYS1,CDH3,TWIST1,NOTCH3,NFKB2,DVL2,MAP3K3,AKT1,KREMEN2,PTGER4,DUSP4,CD40,FANCE,CDC25C,CASP4,MAP3K6,SOCS3,STAT6,STK38,PTK7,LIFR,ABCA1,FRMD6,TGFBR1,JAG2,FZD6,PPP2R3A,KIF5B,MYCL,SGK1,BUB1,SYK,DUSP1,HES1,RHOA,ADAM17,WNT10B,AMFR,RC3H2,MAML2,BCAR1,MAPK8IP1,BCL10,USP6,CASP7,RND3,NEIL3,FGF18,RAP2C,DTX4,ARRB1,OTUB2,GEM |
| 8.418e-10 | -20.90 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | 363 | 97 | 17758 | 2588 |
SPRED1,KIF3C,IL15RA,LGR4,TP53,IL13RA1,OSR2,CA8,MNS1,CENPN,ECI1,SP100,NPNT,LMO4,ALDH1A3,CTTN,RNASEH2A,TSPAN1,CD55,FIGNL1,SH3BGRL,ITCH,SYNE2,C3orf52,EZR,LOXL2,H2AFV,ZFAND5,PRIM1,ALDH5A1,ABHD12,P4HA2,WWTR1,LRIG1,STAT1,ZNF165,PLXND1,ANXA9,GLCCI1,GEN1,E2F8,PRR15,FAM89A,GLIS3,TAB3,FXYD3,CYP2J2,ABCG2,HMGN3,B4GALT4,S100A2,PSIP1,PPP2R3A,PARM1,H1FX,HLA-A,RASSF8,E2F7,ADD3,OXCT1,ITGA3,SLC16A6,BMP7,DRAM1,FXYD5,CACNA1D,TMEM8A,SYK,SLC35A1,C9orf72,MCCC2,RAB3B,HMGN5,CTNNAL1,ASPM,MICB,PLAUR,PIK3R1,CCDC34,EPHA1,AIF1L,KIF11,STEAP1,LEPR,KLHL2,BCAR3,HLA-B,TJP3,ETS2,PLOD2,COL13A1,TMEM30A,RAP2C,ARRB1,PTGES,PKIA,EHD1 |
| 8.671e-10 | -20.87 | negative regulation of phosphate metabolic process | biological process | GO:0045936 | 511 | 128 | 16441 | 2455 |
CASP3,PPP4R4,IBTK,DNAJC3,NDRG2,CCNB1,PDGFB,TP73,CALM2,CDKN2C,RGS3,DLG1,DUSP10,CRY2,PLK1,TNIP1,ITCH,PBK,CDA,EZR,PRKAR2B,EDNRA,ENPP1,CAMK2N2,TRAF3IP1,PPP2R4,SPRY4,HSPB1,F2RL1,LMTK3,CDKN1C,UBASH3B,CALM3,FBLN1,DUSP5,SH3RF2,MECOM,TFAP4,RB1,IGF1R,FBXO7,PAK2,SORL1,MAPK7,SOCS5,CALM1,EPHA1,ILK,RANBP9,PRKAG2,SEMA4D,PLPP3,STK39,XDH,DRD1,EGLN1,SPRED1,NF2,FOXM1,IQGAP1,CTDSPL,TP53,P2RX7,SYTL2,IER3,PDGFA,DACT1,CDKN1B,TWIST1,DAB2IP,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,SIRT1,PPIF,CAMSAP3,BAG4,AKT1,DMTN,COX11,PKMYT1,DUSP4,DAG1,C3orf33,SOCS3,IRS2,DNAJC10,PTPRJ,PPP2R5A,STK38,CORO1C,WWTR1,SLC27A1,RGS14,PRKAR1A,CTDSP1,ARFGEF3,FARP1,PINK1,PSMD10,TRIB2,PKN1,GSTP1,TIPRL,SH2D4A,CD109,PTEN,BMP7,BAX,H2AFY,HEXIM2,SPRY2,DUSP1,RHOA,PPARA,MAPK8IP1,CDK5RAP1,LEMD2,SWAP70,PRDX3,ARRB1,LRRK1,GPER1,UBE2C,HIPK3,PKIA |
| 8.671e-10 | -20.87 | negative regulation of phosphorus metabolic process | biological process | GO:0010563 | 511 | 128 | 16441 | 2455 |
CASP3,PPP4R4,IBTK,DNAJC3,NDRG2,CCNB1,PDGFB,TP73,CALM2,CDKN2C,RGS3,DLG1,DUSP10,CRY2,PLK1,TNIP1,ITCH,PBK,CDA,EZR,PRKAR2B,EDNRA,ENPP1,CAMK2N2,TRAF3IP1,PPP2R4,SPRY4,HSPB1,F2RL1,LMTK3,CDKN1C,UBASH3B,CALM3,FBLN1,DUSP5,SH3RF2,MECOM,TFAP4,RB1,IGF1R,FBXO7,PAK2,SORL1,MAPK7,SOCS5,CALM1,EPHA1,ILK,RANBP9,PRKAG2,SEMA4D,PLPP3,STK39,XDH,DRD1,EGLN1,SPRED1,NF2,FOXM1,IQGAP1,CTDSPL,TP53,P2RX7,SYTL2,IER3,PDGFA,DACT1,CDKN1B,TWIST1,DAB2IP,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,SIRT1,PPIF,CAMSAP3,BAG4,AKT1,DMTN,COX11,PKMYT1,DUSP4,DAG1,C3orf33,SOCS3,IRS2,DNAJC10,PTPRJ,PPP2R5A,STK38,CORO1C,WWTR1,SLC27A1,RGS14,PRKAR1A,CTDSP1,ARFGEF3,FARP1,PINK1,PSMD10,TRIB2,PKN1,GSTP1,TIPRL,SH2D4A,CD109,PTEN,BMP7,BAX,H2AFY,HEXIM2,SPRY2,DUSP1,RHOA,PPARA,MAPK8IP1,CDK5RAP1,LEMD2,SWAP70,PRDX3,ARRB1,LRRK1,GPER1,UBE2C,HIPK3,PKIA |
| 8.734e-10 | -20.86 | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP | MSigDB lists | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP | 275 | 79 | 17758 | 2588 |
MTM1,SLC25A24,S100A11,EPHX4,CAMK1D,CA8,EMP2,DENND2D,SH3KBP1,C1orf116,CCNA2,CDH1,NPNT,CAPG,STEAP2,TACSTD2,HYLS1,EGLN3,FAR1,IL10RB,MGAT5,SP5,CPD,THRB,ERMP1,CENPA,TIMP2,CITED4,FZD4,USP18,PBK,CDC20,GALNT7,DUSP4,PDHX,VCP,SOCS3,PLCH1,ENPP1,MFAP3L,ATP1A1,KLF5,SERPINB6,MLKL,F2RL1,ANXA3,CMAS,LGALS3,MACC1,CCM2,SOX9,GNE,CDCA8,EFHD2,PBX3,ISYNA1,PGAP1,LGALS3BP,CXCL16,SPP1,TIMP1,OXCT1,KCNN4,TNFRSF12A,MAPK11,SLC12A2,ARAP2,PLSCR1,PLAUR,NFIB,PRPS2,CDCA5,RAB31,DTX4,SERPINB5,CLMN,TMEM173,ARHGEF4,ABCG1 |
| 9.067e-10 | -20.82 | DURAND_STROMA_S_UP | MSigDB lists | DURAND_STROMA_S_UP | 280 | 80 | 17758 | 2588 |
NCKAP5,IL15,NDRG1,TSC22D3,MORC4,GATA3,NDRG2,PHOSPHO1,IL13RA1,CHST2,TSPAN6,RTKN2,IFIT1,PDE4D,LGMN,PXMP4,LRP11,LOXL1,SULF2,COL6A2,CAPN6,SLC39A8,PYGO1,ZNF618,C3orf33,DPYSL3,RTN4RL1,POPDC3,STAT1,INPP4B,EFNA5,PLXND1,ST3GAL1,SLC27A3,CDKN1C,CYP2J2,UBASH3B,NES,SLC1A3,SEPP1,FBLN1,TSPAN7,SRPX2,B4GALNT1,DTX3L,B3GALNT1,SPP1,A4GALT,FUT8,TFAP2A,TRIM21,NCAM1,CYP26B1,ADAMTS2,LONRF3,WNT10B,CORO2A,OXR1,CRIP2,CALCRL,MEST,MMP15,MAGED2,IL1R1,PTPRF,EPN3,SLC4A4,FAT4,FGFR2,MATN2,CSGALNACT1,ARRB1,OSMR,CDK18,HOXB13,LTBP2,JAK3,SERPINB1,AHR,RAB3IL1 |
| 9.078e-10 | -20.82 | YAMAZAKI_TCEB3_TARGETS_DN | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_DN | 205 | 64 | 17758 | 2588 |
SPRED1,ST13,TTC39B,GNPDA1,TUBB4B,SLC25A13,CUL4B,SOD2,COL18A1,SLC20A1,EPCAM,CDH1,AKR1B1,CLDN4,CDH3,ASH2L,CKS2,SULF2,PSRC1,TFAP2C,NUSAP1,KCNK1,KPNA2,CBX7,COBL,FGD1,CMAS,GCLM,KLF2,WASF3,LGALS3,CDKN1C,LBR,PSIP1,SIX4,TOP2A,SPP1,IGF1R,NEK2,SORL1,ALDH7A1,IGFBP2,PIM1,ZMYM1,MCCC2,MSH6,S100A6,TGIF1,ALDH2,KIF20A,TCFL5,MYBL2,TCF7,YES1,KIF11,G2E3,MAP1B,SPINT2,CDCA7L,SLC25A40,AURKA,HMGA1,FZD5,JARID2 |
| 9.373e-10 | -20.79 | prostate-carcinoma-adenocarcinoma | COSMIC cancer mutations | prostate-carcinoma-adenocarcinoma | 13006 | 2015 | 17775 | 2585 |
HECA,FAM160B1,IBTK,GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,TRAPPC8,TGOLN2,BAIAP3,ISOC2,DPP8,SNX9,FAM46C,SPSB1,CARD10,LTBP3,ZNF275,GRM5,LYPD5,CDKN2C,NPM2,NAPG,MUC4,PAQR5,ATP13A3,DNM2,CRY2,PPP1CA,TMEM37,RNF26,WBP4,TIAM1,IL10RB,CPE,TIPARP,MGAT5,CCDC74A,NEK4,UXT,DSTN,CDA,KDELR3,TMEM151A,TFAP2C,PRKAR2B,PNKD,ABR,ARF4,LCP1,PIAS3,ENPP1,PLCG1,MID1IP1,C17orf51,ATP7B,CELF5,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,STARD13,ANXA11,ZNF720,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,TFAP4,FLII,RAC2,ZCCHC17,FRY,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,FBXL14,PCYOX1,MAP3K9,SLAIN2,CADPS2,USP38,ALPK1,CNGA1,PANX2,MAPK7,ZMYM1,MOXD1,MYLIP,DGKG,KANK3,NUP85,TTLL1,MCCC2,PAQR7,HPS3,PQLC3,SHARPIN,ZNF503-AS2,FHL2,KIF20B,NPHP3,GOLT1A,DPYSL4,PCTP,SFXN5,GNA11,PSMA4,PLIN5,MAGED2,IL1R1,CACHD1,FNTA,ETS2,DGAT2,CLMN,OSCP1,CBX5,ADAMTS16,DMPK,DOCK9,WDR63,TPRN,NQO1,LFNG,RHBDL3,PTTG1,APOO,GRK6,MGST2,FAM91A1,MOCS1,REPS1,KIAA1147,APPBP2,RBM23,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,TAX1BP3,RASGEF1A,LRP11,ZNF365,MYT1,SNX10,TMCC2,MX1,SNX8,COL6A2,ERMP1,RIPK2,APOBEC3D,PFKFB2,AGPS,PTPN9,SEPT6,VPS4B,SYP,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,EBF2,GIGYF1,SPIN3,PDLIM3,CCNB3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,DMWD,PRIMA1,SLC25A30,CTHRC1,MZT1,MPZL1,FAM189A2,CKAP2,GCAT,ESRP1,BACE1,TRAF2,BIK,HABP4,CCM2,SDC4,BTN3A1,CTSZ,ZNF219,IFT27,CTNNBIP1,DIRAS3,ZFX,PDCD10,FUT2,ITGB8,KNDC1,GPC3,MGAT4A,TMEM62,TUBGCP6,FAM20B,FAM102A,RAG1,CASD1,PARP9,ACBD5,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,AK4,PGBD1,RAB3IP,C4orf27,CNTNAP1,RPL12,PROM1,LDLRAP1,PLOD2,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,PPM1H,ITGAV,OSR1,CMPK2,CD81,ACOT7,SRSF9,PHC1,TLL2,TMEM131,CCNI,TNK1,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,NDRG2,DNAJB11,TEX2,F11R,GALM,MGAT5B,ITPR2,SPTB,SLC9A3R2,FANCI,TFAP2E,PLS3,SUSD2,CPNE2,INPP5E,ENTPD4,NUP210,TM9SF2,CTNNB1,P4HB,NPNT,IL6ST,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,SMAGP,PLK1,KRT80,THRB,MARK1,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,NKAIN1,ARFRP1,EAF2,SESN1,TRUB1,DZIP1L,KDM4D,TRIM9,TNS4,PLEKHG6,PI4K2B,HS6ST1,TRAM2,KCNMB4,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,KLF11,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PARP12,RUNX2,USH1C,HJURP,DNAJB2,FXYD3,RASA2,PSMD7,PDCL,SORBS3,RAB6A,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,WNT3A,NTN1,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,PRX,NMT2,C18orf8,RASGRP2,FOXD2,FA2H,KBTBD2,OTUD6B,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,CDAN1,USP43,RAD21,CTDSPL,TMX4,TP53,RHPN2,P2RX7,BAHD1,STIL,PDGFA,TTC21B,WDR44,TACC2,LMO4,PPME1,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,ZNF628,IDE,PTPRJ,ABHD12,RBL1,STK38,MMP17,MAOA,XRCC3,CHMP4B,EFNA5,SYT13,ARHGAP4,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,PINK1,CDH22,CPEB4,TAB3,KLHL13,CTSB,SCD5,GNAL,MCTP2,HAL,CDCA8,ERCC6L,ERI2,GDF15,HMGN3,LBR,VPS26A,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,UBE2J1,TFAP2A,GTF2F2,IL17RA,TRIM21,SGK1,CPLX1,TSPAN13,ALDH7A1,HMGCL,SYK,FAM134C,ATP2B1,DUSP1,NFE2L3,P2RX4,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,CRIP2,STMN3,PRICKLE1,DPP9,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,USP6,DDX23,CNOT2,DDAH1,SMTNL2,NEIL3,NIPSNAP3A,FGF18,SH3BGRL2,ICOSLG,HIPK3,ARHGEF9,ARHGEF4,GOLGB1,FAM171B,LAMP1,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,VANGL1,TMEM86B,TSC22D3,C1orf198,CUL1,PDGFRL,PSME1,CAMK1D,NANS,SEPT4,VASH1,OAT,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,CYP1A1,ANKS6,STIM1,OSBPL3,SERINC2,POLL,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,METAP2,SPATA18,ACVR1C,CDYL,BNIP3L,SLC35C1,KIF13A,LDB2,POR,RAB2B,PRIM1,ANKRD10,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,SERPINI1,SPRY4,WBSCR27,F2RL1,SLC31A2,CCDC97,FGD1,SEMA6B,RECQL,MRC2,SCOC,TBC1D1,TMEM55B,PRKAA1,AKAP17A,TXNDC9,APBA1,TNFRSF19,PDXDC1,TSPAN7,SH3RF2,MESDC2,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,AIM1,MSH2,DAPK1,TMEM51,PRKG1,TPST1,ADCK2,OSTF1,CACNA1D,DLX4,KCTD3,GPR161,SOCS5,TRAK2,GFPT1,GCC2,PRODH,KCNJ12,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,DCHS1,PYGL,WHSC1,NPC2,ATP8B3,ANTXR1,NFIB,PDE11A,SLCO4A1,AP1AR,NT5C2,PLEKHH2,TJP3,FAAH,PELI2,C1orf21,MATN2,MPP2,FAM83D,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,CDK18,SAMD8,KLK7,ZBTB34,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,CAPN12,GPR107,ST14,CCDC110,THRA,NDRG1,RALBP1,CERCAM,ATP2C2,FAM78A,FTH1,BCL2L1,TMEM170B,FLT3,CYP39A1,ZFYVE9,EPS8L2,EPM2A,C11orf84,CD46,APOBEC3B,NOV,ACAP2,TRANK1,EPHB4,RNASEH2A,TSPAN1,FLOT2,MED30,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,CLSTN1,UTRN,TMEM144,ATP1B1,PYGO1,CBL,B3GALNT2,ITPR3,ASB13,ALCAM,TRIQK,ATP10D,ZMPSTE24,ACAD10,CCDC149,ZNF704,COBL,CBX7,MAMDC2,PRKAR1A,PLSCR4,DEPDC1,IGFBP6,HAPLN3,SLC41A1,CENPI,EPS8,NES,HERC5,PBX3,PLD2,DNAH3,EFNB1,FGF19,HLA-A,WWP2,CKAP5,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,ERBB3,CITED2,TTPA,MSH6,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,PAPD7,TCFL5,ZKSCAN2,FBXO9,DIAPH2,UBAC1,YES1,GRTP1,ARSK,KIF11,CDK5RAP1,CRTC2,DCTN6,ACADSB,DGCR2,SEC14L4,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR62,WDR91,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,FAF2,UGT8,CRYM,VARS2,MPP5,TRIM68,ECI1,HTR1D,ADPRHL1,ZFYVE16,EPCAM,SIPA1L2,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,STK35,LAMP3,CYP1B1,CXXC5,CENPA,ASXL1,LAP3,ITCH,ACBD3,USP18,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SH3GLB2,ZNF165,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,PPP1R12A,SERPINE2,BVES,PYROXD2,ETV5,ABCG2,CALM3,PM20D2,FAM81A,QSOX2,SPP1,TYW3,B3GALNT1,PFKL,FAM20C,OCRL,COL6A1,PRKCI,SRP54,LIMCH1,BRAT1,C10orf54,NPTN,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,SNED1,MDFI,ELK3,PODXL2,SPA17,PDE5A,KIAA1109,PRRC1,HEATR5A,NUBP1,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,SOX13,INSR,UAP1,TMEM30A,SPAG7,DCUN1D1,SH3BP4,RAB31,NXPH4,DONSON,CTSA,SHROOM2,JAK3,COL16A1,AFAP1,RARG,SNX30,DRD1,CCNE2,LMO7,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,EXT2,KCTD9,MXD1,SAP130,ZNF687,CYP4F11,KIF14,REEP1,ZBTB49,DIXDC1,EPB41L4B,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,SOAT1,RFK,PTPRU,MRPS35,GLO1,CD40,TMTC2,CDC25C,PDHX,CASP4,ARHGAP35,HSF4,ALDH5A1,STAT6,SECTM1,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,SHPRH,SH3D19,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,RBP7,XPR1,HMGXB4,ITGA2B,HDAC9,TMEM63A,SYDE2,KIF5B,TOP2A,MZT2A,TAF1B,ADRBK1,LLGL2,A4GALT,BMP7,MYCL,TOX2,RRBP1,ACTA2,H2AFY,ARVCF,KANK2,C12orf75,SLC35A1,RPGR,MYO5A,RBMS2,DCAF6,SYBU,RC3H2,TTC7A,RUNX3,FAM73B,NDRG3,LEPR,FOXL1,LEMD2,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,TRIM69,RND3,FIBCD1,SPINT2,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,NGEF,ACACB,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,SMARCAL1,MMADHC,CACNA2D2,DHX8,FAM102B,NRG2,LYNX1,LGI3,MORF4L2,SYTL4,CNTROB,CA8,BARD1,KIF26A,PHF1,EPDR1,DAPK2,TP73,WEE1,PSMD1,TGFBR3,RGS12,AP1M2,ARHGAP42,PQLC2,KIAA1107,DNAH6,CYP2S1,CABP1,PPP1R16A,SLC46A1,RDH14,KLF3,ALDH1A3,FUT1,SEMA3G,ACOX2,PIK3CD,TINAGL1,ODF2L,ERAP2,TUBA4A,NWD1,SMARCA2,TNIP1,SH3BGRL,SERTAD4,RNF11,MTRF1L,LOXL2,F12,PPP1R14C,ICMT,MYOM1,CYP4F3,COL12A1,SLC44A3,PGF,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,RELL1,LSM14B,PDPR,GAB1,E2F8,NFKBIE,ALDH6A1,FAM169A,TMTC3,CYP2J2,SOX9,STRN4,SLC36A4,MERTK,LMNA,RAVER2,GNS,DNPEP,WDFY1,FAM189A1,CD22,ZIC5,FAM13B,STT3B,NCAM1,NDUFA12,C9orf72,EPHX1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SPTLC2,DCP2,CYB5A,RHOB,STK17A,DHX32,PTPRF,SCARB2,NCOA3,NAAA,HTT,SEMA4D,SETD3,TEX30,ITPR1,DYSF,AURKA,OSMR,ALG2,ARPC2,DRP2,NDE1,SERPINB1,ZNF502,TRPC3,RPS6KA3,CSRP2,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,FAM131C,ACTR8,WDTC1,RGS20,ETNK1,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,ZNF385B,CDS1,UHRF1BP1L,CCND1,RNF220,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,SCN3A,RNF169,ENPP4,CAMSAP3,SSH3,PSRC1,LGALS8,FZD4,NRBF2,SYNE2,CDCA2,NUSAP1,RAB38,IRS2,STX10,TTC12,SIPA1L1,WWTR1,INPP4B,PLEKHG1,PDXK,RGS14,ARNT,TTC8,GALK1,FARP1,NKX3-1,TNRC6C,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,NUCB2,KCNC4,SRPX2,HOXB2,TIPRL,ICAM1,NEO1,PDIA4,CAPN2,DTX3L,CXCL16,ANK1,ADD3,IRAK1,SLC27A6,ANKS1B,FAM160A2,ARSG,CTSC,KCNK5,CALD1,FDXR,ADAM15,MAPK11,ZNF230,WWP1,AK3,NPTXR,ITM2C,TPCN1,S100A6,TMX1,CRTAP,HCN3,POU6F1,LCA5,CTNNAL1,FAM160A1,FMN1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,PLEKHA7,DBR1,MYEOV,BLVRA,NEURL1B,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,PITX2,DCAF10,GALNT3,KIAA0141,NR1D2,ACVRL1,CCDC6,ARFGAP3,CENPE,FHL1,NUP37,DCBLD1,CYBRD1,FOXA1,MYL9,SIGIRR,TRIM2,AGRN,FAM199X,PPM1J,EPHA4,FHDC1,NDC80,MCCC1,HDAC6,CDIPT,PDGFB,PIGL,PCNA,SHC3,MKRN3,ELF5,DDHD2,DUSP10,RGS5,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,CD55,HN1L,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,FAM212B,IDH1,CLCN2,LHFPL2,ZBTB7B,RHEB,VCP,DPYSL3,OPTN,MFAP3L,PLCH1,WIPI1,MAP2,P4HA2,DOLPP1,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,POMT1,GLCCI1,MAFF,PRKAA2,BMF,UBASH3B,ZCCHC24,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,C3orf18,DHRS3,IL18R1,PGAP1,SSX2IP,CORO1B,RB1,KIAA0895,DAZAP1,VASP,IGF1R,EXOC8,MDFIC,TMEM8A,PLCB2,ALDH3A2,PSMA5,C9orf9,CHSY3,CYP26B1,MRPS33,WDR72,CORO2A,TCF7,EIF2AK1,IFIT3,UNC45B,ANKRD29,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,MAPKAPK2,H1F0,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,CTBP1,NIPA1,FAM45A,KCNAB3,NF2,UGP2,UPF3B,FOXM1,XYLT1,DGKA,CCDC68,ERBB2,ZNF28,SLC7A2,FAM198B,C1orf116,SDF4,CYP26A1,PER2,CDK14,ATP6V0B,SRPX,EFR3A,N4BP3,PLCG2,LHX6,GYS1,MINPP1,EGLN3,SCN2A,FAR1,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,TCEB2,FIGNL1,S100A4,COQ10B,DNAJC10,DUOX1,ATP1A1,RTN4RL1,PTK7,ADAMTS14,ANXA9,ZBTB6,C1orf43,RPL22,LTA4H,AIFM3,ZNF701,NDST3,ZC3HC1,CMTM4,MAN2B2,GSDMD,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,RUSC2,DAP,BLVRB,GABRG2,JAG2,DSE,CRABP2,PPP2R3A,SLC9A2,SIRPA,CCDC92,CEP97,SLC35B4,ABCD1,BUB1,KLF9,SLC45A3,FAH,IGDCC4,DLGAP1,HMMR,MLEC,IFITM3,NR3C1,AMFR,PPARA,CCDC34,TRIM35,CAPNS1,AKAP3,FXR2,FNDC3A,BCAR1,MAPK8IP1,CD83,PRDX4,SCRN2,FUCA1,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZNF214,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,PKD2,ACADM,TBC1D4,NDFIP1,SAT2,DIS3L,GAA,PPP4R4,ACVR1,TTC39B,TMEM41B,ATP8A1,FAM129B,KLC2,TAP1,PPFIBP2,GATA3,PLXNA1,CCNB1,PLA2G16,ELMOD2,NCS1,CHST2,SESN3,CTGF,ELMO2,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,PACSIN1,XKR8,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,TNS1,SLC17A5,GALNT7,AURKB,SAV1,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ULK2,ARHGEF26,SGPP1,AHRR,SFXN1,KDSR,RBM47,PTER,GNPTAB,NKD1,FAM110C,DHTKD1,EIF4EBP2,TANC2,UNC5B,TRAF5,RTN3,LZTS1,DLAT,DDX58,KLF2,MRPL44,INPPL1,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,BMP2K,PRRG4,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,NECAB3,BDH1,RUNDC3B,OPN3,CTPS1,SORL1,CD70,PIKFYVE,CTSD,EEF1D,TSPAN33,DNAI1,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,B3GNT7,QSOX1,FADS2,MFI2,KIAA1841,MMD,TBC1D8B,MICB,AMER1,PTPRH,ANO6,KCTD20,VEZT,FAM133B,PKM,KDM3A,FBXO10,GLT8D2,STX3,RASA1,DGKH,GABRD,PRKAG2,ISM1,DCK,NAB2,SLC4A3,FGD6,PCDH19,NR4A2,EFNA1,MAP3K5,NRBP1,PKD1L2,PLEKHG3,FRMPD3,PLA2G4A,CEP70,TRIP10,S100A11,TMEM217,NLRX1,BROX,SUZ12,IQGAP1,RPS6KA1,IRX4,EGR3,CD274,NUDT12,AIFM2,MNS1,TMPRSS4,GNB2,APLP2,ZNF75D,DOK4,FICD,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,PHKA2,NR2C1,TMBIM1,GPX4,TBC1D10B,MYO5B,SLC5A11,SEC23A,TMEM43,CAPN6,TEP1,COX11,PRKCQ,BCL7B,AKR1E2,H2AFV,SP4,ZNF469,CMTM7,PRDM11,NIN,OSBPL2,EPHA10,FYN,ZNF641,PPP2R5A,JAK1,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,ZC3H12B,B4GALT3,NR3C2,ATMIN,DENND5B,OTUD5,MRPS9,WASF3,NUDT6,ARHGEF3,SLC16A14,ATP9A,ARL4C,CCNJL,GPR180,CYB561,SPR,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,C16orf59,FAM111A,OXCT1,PHF7,PTEN,CENPJ,PRC1,ATP8B1,SLC44A2,TAGLN2,MAP3K7,CNOT6L,GFI1,TRIM62,NCOA2,OSGIN1,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,ERMAP,MPP1,PARP4,FURIN,LRRC1,GPLD1,NUCB1,RGS9,MAMDC4,PRDX3,RCBTB2,AMMECR1,SLC25A40,PGM2L1,SERPINB5,CCDC69,GRIN2D,ETAA1,SLC25A38,ARSB,NCAPG2,OCLN,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,TMEM184B,ST13,HEBP1,CPT2,EPHX4,UBE2Z,TAF6L,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,CHPF,ARHGEF10L,NKAIN3,LRRC6,GRHL1,ZCCHC12,DPYSL2,IMPAD1,PHTF1,DLG1,CAPG,POF1B,ANKRD12,AKR1B1,KIF22,RAB20,SUN3,RP2,NFU1,ARNT2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,FGFR1OP2,OLFML2A,TDP1,ATL1,TRIM8,SOD1,SYNE3,ASCL5,FOPNL,RNF165,ROR1,MRPS18A,PTGFRN,MRPS36,ADRBK2,STK17B,TCN2,SEC14L2,EDNRA,CXXC4,LRRC42,ZNF114,ARHGEF19,NEIL1,FASTKD1,DHRS13,UEVLD,IARS2,TRIM45,CCDC74B,ADIPOR1,APBA2,RAP1GAP,PPP2R5D,MIIP,CPPED1,STARD3NL,LRRFIP2,PEX6,ELOVL7,ASL,ATP6V1E2,SAMD9,PHLPP1,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,KCNN4,EBF4,FXYD5,FNIP1,ZNF692,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,HP1BP3,PARD3B,OXR1,FBXO8,BTN3A2,AMDHD1,EGFR,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,TSC1,ONECUT1,SLC6A6,UTP14C,CGREF1,NFKBIA,ALPK3,RHOBTB2,PITPNA,EGFL7,KIF12,PROM2,FBXW5,KLF7,ZSWIM5,FAM92A1,IL15,SLC2A8,PSME2,ABCG4,GMPR,TDRKH,MICALL2,SS18,SLC25A48,KHNYN,SETDB2,FRYL,SMO,RPN2,TWIST1,GOT1,APIP,PDIA6,LOXL1,F2R,HSPA2,SCYL3,FRS3,ZNF525,BAG4,TAF5,KREMEN2,SLC39A8,OSTM1,IGSF8,DUSP4,SNAPC2,DOCK5,BFSP1,PEX2,CANT1,VSIG10,PLXND1,AKNA,SGOL1,LIFR,CBX4,CCDC24,ANXA3,CDS2,SORT1,POC1B,JKAMP,LRP4,FAM134A,AES,NOTUM,TRMT2B,POMGNT1,FAM167A,ZNF212,IL17RB,IRF2BPL,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,BRD7,IQGAP3,SUN2,ADAM17,RAB3B,GCLC,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MPV17L2,MAP1B,KLHL2,HLA-B,C2orf70,UBE2D2,TADA2B,OTUB2,GLB1,HOXB13,SOX8,L1CAM,LRRC57,SNPH |
| 9.583e-10 | -20.77 | GSE6269_HEALTHY_VS_STREP_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_STREP_AUREUS_INF_PBMC_DN | 165 | 55 | 17758 | 2588 |
GRN,SEMA6B,SORT1,LGALS3,S100A11,CD63,CTSB,BLVRB,SOD2,FTH1,DSE,PRRG4,SIRPA,ICAM1,MXD1,APLP2,ZYX,TIMP1,H2AFY,STEAP3,RAB20,MARCH2,CTSD,CDKN2D,IL1RAP,CKAP4,LAMP2,CPD,PPIF,P2RX4,TIMP2,MPP1,PLAUR,VAMP3,BNIP3L,NPC2,ZFAND5,RNF19B,ZDHHC3,ARF4,RHEB,SOCS3,SERPINA1,HPSE,H1F0,PELI2,NOD2,DYSF,ADIPOR1,NRG1,HS3ST3B1,PLIN3,SERPINB1,CYBRD1,RRAGD |
| 9.858e-10 | -20.74 | caecum | COSMIC cancer mutations | caecum | 14975 | 2278 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,HTATIP2,SYP,DNAJB14,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,PLA2G15,ACOT7,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,ZDHHC21,FOXP2,LYPD6,IL17RA,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,KCNS3,IRF2,SNX16,SGCE,SPATA18,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,TCF25,DDIT4L,ATP2C2,FAM78A,CYP39A1,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,KIF11,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SPA17,PDE5A,KIAA1109,PRRC1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,RAB31,NXPH4,CTSA,TOB1,RARG,AFAP1,SNX30,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,GLO1,CDC25C,FANCE,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,PDPR,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,SNTB2,HSPA12A,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,B3GNT7,KIAA1841,ZNF84,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,PLA2G4A,TRIP10,S100A11,TMEM217,SUZ12,CAST,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,CPEB2,HEBP1,CAMKK1,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,RAB3B,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,SNX9,CARD10,LTBP3,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PAQR7,HPS3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,LFNG,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,SNX10,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,CXorf57,AK4,C4orf27,LDLRAP1,PROM1,PLOD2,DBI,SSNA1,ITGAV,CMPK2,OSR1,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,EAF2,SESN1,KDM4D,TNS4,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,WDR44,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,STK38,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,GDF15,LBR,AIP,PARM1,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,RPL39,VASN,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,GPR107,CAPN12,REPS2,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,TMEM170B,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,CD46,RALB,RNASEH2A,EPHB4,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,ECI1,HTR1D,ADPRHL1,SIPA1L2,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,ADRBK1,TAF1B,LLGL2,A4GALT,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,CSGALNACT1,PLOD3,AHR,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,MANF,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,SLC44A3,PGF,LIMK1,MAP3K11,RELL1,E2F8,GAB1,NFKBIE,STRN4,ZNRF3,MERTK,RAVER2,GNS,WDFY1,FAM189A1,CD22,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,PTPRF,SCARB2,DYSF,OSMR,MDH1,SERPINB1,RPS6KA3,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,SDC1,CNTRL,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,ING1,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,NDST3,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,ACADM,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,SLC25A5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,SLC11A2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,CASP3,LTBP1,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,DLG1,ANKRD12,AKR1B1,POF1B,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,FOPNL,RNF165,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,PAPD5,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,SLC2A8,GMPR,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 9.966e-10 | -20.73 | identical protein binding | molecular function | GO:0042802 | 1181 | 250 | 16491 | 2452 |
ACVR1,ST13,ADD1,GRIK2,TRIM5,CRYM,EPHA4,HEXB,NDC80,TAP1,DHX8,OAT,SNX9,PDGFB,ERP29,SLC8B1,BARD1,ECI1,SLC9A7,PICK1,TFAP2E,TP73,DAPK2,HSF2,PCNA,STIM1,IL6ST,CABP1,ALDH1A3,CLDN4,SNX16,PTPRE,S100A13,APOBEC3G,SMAGP,FGFR1OP2,RASGRP1,OLFML2A,ATL1,SOD1,TRIM8,CDA,BNIP3L,CR2,CCBL2,PRKRA,IDH1,MYOM1,TP53I3,TYSND1,VCP,PLEKHB1,LCP1,OPTN,TRIM9,ENPP1,DNM1L,TBX1,PPP2R4,MAP3K11,ADIPOR1,GLA,HSPB1,RAP1GAP,E2F8,DDX58,HJURP,ABCG2,PSMD7,GPSM2,FBLN1,S100A2,ANO1,CORO1B,MECOM,TFAP4,RB1,IGF1R,PIK3AP1,PFKL,BHLHE41,FLRT3,PAK2,MSH2,DAPK1,MAP3K9,SELK,AHCY,NCAM1,ALS2CL,CCDC88A,GCC2,RGMB,ANO6,SHARPIN,FHL2,PIP4K2C,PYGL,VWA1,EIF2AK1,KIF20B,IFIT3,EGFR,SMN1,PLIN5,FAS,NUDT16,PLEKHH2,UAP1,HTT,PVRL2,DCK,CSF1,PRPS2,NFKBIA,SH3BP4,DGAT2,S100A5,NR4A2,MAP3K5,NDE1,CBX5,HOOK1,NRBP1,CTBP1,TMEM173,XDH,LZTFL1,UGP2,NQO1,S100A11,TRIP10,THRA,SOD2,TP53,ABCG4,P2RX7,COL18A1,ERBB2,MAPK4,BCL2L1,FLT3,EXT2,MNS1,SDF4,PDGFA,APLP2,SP100,SRR,PLK4,BRI3,DAB2IP,GOT1,TWIST1,ECE1,APIP,NAGA,NR2C1,DVL2,FRS3,SEPHS1,SNX8,SIRT1,GCA,CLCN3,RIPK2,AKT1,FZD4,S100A4,VPS4B,SYP,GTF2A2,MYPOP,PTGS2,IDE,ALDH5A1,PAFAH1B3,STK26,BHLHB9,STAT6,WWTR1,KIAA1804,STAT1,TLE1,SLC27A1,CHMP4B,ANXA9,PDXK,BIN1,PACSIN2,TRAF2,LRP4,CBLL1,SRPX2,ITGA2B,ZNF212,FOXP2,TOP2A,E2F7,PDCD10,CARD8,OXCT1,IRAK1,CTSC,PTEN,CST3,PRC1,BAX,TFAP2A,TRIM21,HMGCL,ABCD1,ERBB3,RAG1,TPCN1,S100A6,CAMK2G,MSH6,AMOTL2,PVRL4,P2RX4,PDGFC,SUN2,HES1,SHMT1,FBLN5,NADK2,DPP9,COL7A1,FXR2,FAM109A,LEPR,PRDX4,PITX2,CD8A,SERPINA1,FGFR2,RAB11FIP2,PRDX3,TBX18,NR4A3,PKD2,SSNA1,ACADM,LRRK1,USF2,L1CAM,ACOT7,ESYT2,ABCG1 |
| 1.026e-09 | -20.70 | MANALO_HYPOXIA_UP | MSigDB lists | MANALO_HYPOXIA_UP | 201 | 63 | 17758 | 2588 |
ENO2,ZNF395,CDKN1C,NUAK1,HLA-E,NDRG1,ARL4C,COL18A1,NENF,ITPR2,TRIB2,SEPT4,PDGFB,PHLDA1,SPSB1,IER3,RPS6KA2,FAM46A,CYP4F11,RGS3,N4BP3,PLCG2,OPN3,BCL6,LIMCH1,EGLN3,CLIP2,MAST4,KANK3,PGM1,HES1,CASK,ALDH2,PLEKHO1,DCHS1,BNIP3L,AK4,DIAPH2,TNS1,LOXL2,KDM3A,LEPR,GLCE,PTPRF,PGF,MAGED2,HLA-B,ENPP1,INSR,PLOD2,CDK19,P4HA2,AXL,PELI2,ALPK3,TLE1,KLF11,GRAMD1C,SHOX2,MAFF,ABCA1,AFAP1,EGLN1 |
| 1.040e-09 | -20.68 | GNF2_MKI67 | MSigDB lists | GNF2_MKI67 | 27 | 18 | 17758 | 2588 |
HMMR,CENPA,ZWINT,KIF20A,FOXM1,ASPM,CDC20,NUSAP1,KIF11,CDK1,TOP2A,CCNA2,PCNA,AURKA,CENPE,UBE2C,ESPL1,MELK |
| 1.052e-09 | -20.67 | ENK_UV_RESPONSE_EPIDERMIS_UP | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_UP | 276 | 79 | 17758 | 2588 |
SLC25A13,RGS20,PKP2,PRSS22,MPP5,FTH1,BCL2L1,GRK6,TMPRSS4,CHST2,ZYX,RALB,PRICKLE3,IL6ST,ALDH1A3,GYS1,TUBG1,CDH3,MTMR11,MANF,CERS2,MX1,CYB5R2,CDC20,ARHGDIB,F12,TP53I3,PRIM1,PGF,CARHSP1,PAFAH1B3,HPSE,PSMD3,MYLK,HDAC1,NRG1,IRF7,RAP1GAP,CBX4,ANXA3,CMAS,GCLM,CTSB,ETS1,PSIP1,ZNF212,M6PR,ELF3,CAPN2,CA2,ITGA3,FUT2,CES2,FDXR,DAPK1,FXYD5,SORL1,MYLIP,ULBP2,PSMA5,HP1BP3,SNX7,MDFI,NAGPA,DDB2,PLSCR1,IFITM3,PYGL,SERPINA1,PRDX3,HTT,CSF1,RAB31,CSTF2,OSMR,STK39,SERPINB1,ESPL1,KLF7 |
| 1.166e-09 | -20.57 | large_intestine-caecum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-caecum-carcinoma-adenocarcinoma | 14963 | 2276 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,HTATIP2,SYP,DNAJB14,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,PLA2G15,ACOT7,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,ZDHHC21,FOXP2,LYPD6,IL17RA,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,KCNS3,IRF2,SNX16,SGCE,SPATA18,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,TCF25,DDIT4L,ATP2C2,FAM78A,CYP39A1,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,KIF11,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SPA17,PDE5A,KIAA1109,PRRC1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,RAB31,NXPH4,CTSA,TOB1,RARG,AFAP1,SNX30,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,GLO1,CDC25C,FANCE,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,PDPR,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,TFG,SMYD5,XKR8,LAMP2,LOC81691,SNTB2,HSPA12A,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,B3GNT7,KIAA1841,ZNF84,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,PLA2G4A,TRIP10,S100A11,TMEM217,SUZ12,CAST,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,CPEB2,HEBP1,CAMKK1,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,RAB3B,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,SNX9,CARD10,LTBP3,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PAQR7,HPS3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,LFNG,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,SNX10,TMCC2,MX1,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,SLC25A43,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,CXorf57,AK4,C4orf27,LDLRAP1,PROM1,PLOD2,DBI,SSNA1,ITGAV,CMPK2,OSR1,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,EAF2,SESN1,KDM4D,TNS4,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,WDR44,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,STK38,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,GDF15,LBR,PARM1,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,RPL39,VASN,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,GPR107,CAPN12,REPS2,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,TMEM170B,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,CD46,RALB,RNASEH2A,EPHB4,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,ECI1,HTR1D,ADPRHL1,SIPA1L2,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,ADRBK1,TAF1B,LLGL2,A4GALT,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,CSGALNACT1,PLOD3,AHR,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,MANF,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,SLC44A3,PGF,LIMK1,MAP3K11,RELL1,E2F8,GAB1,NFKBIE,STRN4,ZNRF3,MERTK,RAVER2,GNS,WDFY1,FAM189A1,CD22,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,PTPRF,SCARB2,DYSF,OSMR,MDH1,SERPINB1,RPS6KA3,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,SDC1,CNTRL,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,ING1,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,LTA4H,NDST3,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,ACADM,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,SLC25A5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,SLC11A2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,CASP3,LTBP1,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,DLG1,ANKRD12,AKR1B1,POF1B,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,FOPNL,RNF165,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,PAPD5,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,SLC2A8,GMPR,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.173e-09 | -20.56 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | 248 | 73 | 17758 | 2588 |
CASP3,KIAA1462,TSC22D3,CUL4B,PHOSPHO1,KCTD12,BCL2L1,EMP2,SH3KBP1,CDK14,DPYSL2,PAQR5,KLF3,STEAP2,STEAP3,IL1RAP,SMAGP,LGALS8,FZD4,SYNE2,ARHGDIB,RNF19B,CDK1,FZD7,KDSR,PGF,TMEM164,FYN,ATP1A1,JAK1,RAB11FIP1,MAPK13,HS3ST3B1,CPPED1,IER5L,CD99,KLF2,FARP1,DCAF7,HLA-E,EFHD2,EFNB1,ICAM1,SIRPA,ZDHHC21,RALGPS2,GATA2,SNX18,BHLHE41,TOX2,DAPK1,OPN3,TSPAN13,IGFBP2,NPTXR,TRIM62,MDFI,P2RX4,FBLN5,SPATA13,PPARA,NEURL1B,SPTLC2,STEAP1,GLCE,FAS,GALNT3,FUCA1,TRIM69,FGF18,NMI,PGM2L1,CMPK2 |
| 1.238e-09 | -20.51 | neurotrophin signaling pathway | biological process | GO:0038179 | 397 | 105 | 16441 | 2455 |
CASP3,SPRED1,RPS6KA1,PSME2,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,ARHGEF16,PDGFA,CALM2,RPS6KA2,PSMD1,SHC3,RALB,PSMC2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,TIAM1,RASGRP1,FRS3,RIPK2,AKT1,CASP9,PRKAR2B,AGO4,DUSP4,ITPR3,ABR,IRS2,PLCG1,FYN,JAK1,NGFRAP1,PSMD3,HDAC1,MAPK13,SPTBN5,NRG1,ARHGAP4,GAB1,PPP2R5D,PSMC1,PCSK5,FGD1,PRKAR1A,MAPK12,ARHGEF3,TNRC6C,SORT1,ARHGEF11,RASA2,ARHGEF7,PSMD7,PSMD10,CALM3,PHLPP1,DUSP5,FGF19,ADRBK1,IRAK1,PTEN,MCF2L,PRKCI,MAPK11,ERBB3,NCAM1,MAPK7,PSMA5,CAMK2G,RASGRF1,ADAM17,RHOA,PSMB4,MAPKAPK3,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,FURIN,ELK1,BCAR1,PSMA4,EGFR,RASA1,MAPKAPK2,FGFR2,PHLPP2,NFKBIA,ITPR1,FGF18,GRIN2D,JAK3,ARHGEF9,RPS6KA3,ARHGEF4,NGEF |
| 1.246e-09 | -20.50 | regulation of cellular component organization | biological process | GO:0051128 | 2113 | 410 | 16441 | 2455 |
SSH1,ADD1,ATP8A1,HEXB,RET,GATA3,PLXNA1,CAMK1D,CCNB1,SNX9,KIF26A,PHF1,PICK1,NCS1,NPM2,CDKN2C,CTGF,DNM2,TACSTD2,SEMA3G,PACSIN1,TIAM1,VPS11,SMARCA2,DSTN,CDA,BNIP3L,NBPF3,PIF1,AURKB,CCNF,SLC25A5,LCP1,ULK2,ABR,ENPP1,MID1IP1,DNM1L,PLK2,LIMK1,TRAF3IP1,FAM110C,NOD2,TMOD2,ITPKA,ARF6,F2RL1,LZTS1,FGD1,SEMA6B,TBC1D1,SOX9,FAM21C,MERTK,LMNA,CALR,RAC2,ITGA3,CYR61,MEGF8,FLRT3,VASN,NEK2,MSH2,SORL1,SLAIN2,TNFRSF12A,PIKFYVE,RIMS2,EPB41L5,MFI2,ANO6,PIP4K2C,PLS1,KIF20B,EPHA1,ILK,KDM3A,STX3,RASA1,FAS,PTPRF,AP1AR,SERTAD2,PLEKHH2,HTT,SEMA4D,CSNK1G1,ARAP1,FGD6,AURKA,OSCP1,EFNA1,ARPC2,RPS6KA3,ADAMTS16,EHD1,DMPK,MTM1,FOXO6,DLGAP5,THRA,RPS6KA1,PTTG1,PKP2,BCL2L1,PRKACA,DDR1,APC2,MNS1,EPS8L2,NOV,RALB,CDKN1B,DAB2IP,ACSL4,TSPAN1,CDKN2D,TMBIM1,TBC1D10B,SEMA3B,CAMSAP3,SSH3,CDKN2AIP,PSRC1,CAPN6,DMTN,VPS4B,CLSTN1,PRKCQ,NUSAP1,PKMYT1,CBL,SNX12,PEX5,FYN,PPP2R5A,SHROOM3,CORO1C,AXL,WWTR1,SIPA1L1,TRIOBP,STAT1,KLF5,RAB29,NRG1,GEN1,COBL,PRKAR1A,WASF3,TCAF1,TAOK2,IGFBP6,CKAP2,EPS8,BIK,SDC4,FLOT1,CBLL1,NES,PLD2,HDGFRP2,ETS1,SRPX2,ICAM1,ADGRB2,SIX4,CTNNBIP1,CAPN2,CXCL16,ANK1,IGSF9,PTEN,CENPJ,KNDC1,GPC3,CST3,FAM20B,TUBGCP6,SGK3,BAX,ATP8B1,ADAM15,IGFBP2,CNOT6L,MAP3K7,GFI1,ITM2C,SPRY2,TRIM62,OSGIN1,FARP2,FMN1,RAPGEF2,PIK3R1,EIF5A2,GRIN1,SKA1,KIF11,BTG1,LDLRAP1,FGFR2,ACVRL1,ITGAV,GPER1,CENPE,HMGA1,FHL1,FZD5,ARSB,SHOX2,ESPL1,FOXA1,JARID2,TNK1,AGRN,EPHA4,ARFGEF1,F11R,HDAC6,PDGFB,SDC1,MAP1LC3B,SPTB,SH3KBP1,ZFYVE16,RPS6KA2,CTNNB1,CDKL5,SIVA1,DPYSL2,PSMC2,DDHD2,MITF,CAPG,DLG1,RAB20,MYH14,CTTN,S100A13,NEB,PLK1,ING1,SYNE3,STRIP2,ITCH,EZR,KLK6,EAF2,ANLN,VCP,DPYSL3,TRIM9,TBC1D17,ARHGEF19,GPRC5B,ADIPOR1,PIEZO1,CHPT1,RAP1GAP,PSMC1,MYL12B,GRN,PIFO,BMF,ARAP3,LGALS3,HJURP,SERPINE2,BVES,DNAJB2,ETV5,SORBS3,RACGAP1,NCKAP1,FBLN1,CORO1B,BMP2,SPP1,RB1,VASP,IGF1R,GATA2,KIF13B,TBCD,PRKCI,FNIP1,NPTN,KNTC1,WNT3A,NTN1,ZRANB1,CCDC88A,KIAA1109,NUBP1,CDK5R1,RASGRP2,TSC1,INSR,ITGA7,TMEM30A,CGREF1,CDCA5,SH3BP4,PLD1,SHROOM2,SEMA3A,COL16A1,CTBP1,AFAP1,PROM2,GAS2L1,LZTFL1,SORBS1,NF2,FOXM1,TP53,ERBB2,P2RX7,MICALL2,PATL2,ARHGEF16,IER3,PDGFA,LMO4,KIF14,PLCG2,BCL6,PLK4,VAT1,TWIST1,DIXDC1,ESPN,LMAN1,HSPA2,EBAG9,CHP1,PPIF,SIRT1,BAG4,AKT1,CDC20,SERTAD3,PTGER4,CDC25C,DAG1,ARHGAP35,JADE1,IDE,PTPRJ,BHLHB9,PTK7,XRCC3,CHMP4B,SPTBN5,EFNA5,PLXND1,MAD2L1BP,BIN1,FBLIM1,PINK1,PACSIN2,CD63,ARHGEF11,SH3D19,CIT,ARHGEF7,LRP4,PSMD10,TGFBR1,GDF15,CRABP2,KIF5B,IL17RB,BMP7,KIAA0319,GTF2F2,SGK1,H2AFY,BRD7,BUB1,SYK,FAM134C,MYO5A,HES1,ADAM17,RHOA,FBLN5,WNT10B,PLAUR,RGCC,STMN3,NDRG3,BORA,BCAR1,MPV17L2,MAP1B,ARHGAP24,CNOT2,SWAP70,CTSV,TADA2B,E2F1,ARRB1,TBC1D4,UBE2C,AHR,L1CAM,NGEF |
| 1.267e-09 | -20.49 | cytoskeletal protein binding | molecular function | GO:0008092 | 804 | 182 | 16491 | 2452 |
MYL9,SSH1,ADD1,KLC2,ARFGEF1,KIF2C,HDAC6,FAM101B,KIF26A,MAP1LC3B,SPTB,PICK1,PLS3,CALM2,STIM1,DPYSL2,DLG1,CAPG,DNM2,POF1B,KIF22,RP2,MYH14,PACSIN1,TLN2,RCAN3,MYRIP,NEB,PLK1,KIFC2,SYNE3,SNTB2,DSTN,UXT,EZR,TNS1,KIF13A,ANLN,LCP1,TNS4,MPRIP,MAP2,TRAF3IP1,MYLK,FAM110C,NOD2,TMOD2,EPB41L4A,MYL12B,CAPN1,LASP1,PIFO,SCN5A,INPPL1,USH1C,CALM3,KIF23,SORBS3,RACGAP1,RAB6A,CORO1B,MYO5C,FLII,VASP,KIF13B,TBCD,FXYD5,LIMCH1,CACNA1D,MYLIP,CCDC88A,EPB41L5,DPYSL5,KIF20A,B9D2,CORO2A,CALM1,PLS1,VEZT,KIF20B,ANTXR1,EGFR,AP1AR,FNTA,PLEKHH2,HTT,FAM83D,AGBL5,CLMN,KIF12,NDE1,ARPC2,SHROOM2,HOOK1,AFAP1,RUSC1,GAS2L1,KIF3C,SORBS1,NF2,TMSB15A,NDRG1,MICALL2,APC2,KTN1,EPS8L2,TMSB15B,SCNN1A,CDH1,KIF14,REEP1,ESPN,DIXDC1,EPB41L4B,RAB27B,CHP1,MYO5B,SSH3,CAMSAP3,PSRC1,CAPN6,DMTN,S100A4,SYNE2,UTRN,CLSTN1,KIF1C,NUSAP1,BCL7B,DAG1,GABARAPL1,FYN,ATP1A1,PDLIM3,SHROOM3,CORO1C,TRIOBP,SPTBN5,RGS14,REEP4,COBL,BIN1,WASF3,FBLIM1,PACSIN2,FARP1,EPS8,ARL4C,SNTA1,KIF5B,CAPN2,ANK1,ADD3,CENPJ,CALD1,TUBGCP6,PRC1,KLC3,IQGAP3,CLIP2,S100A6,MYO5A,FARP2,SUN2,RAB3B,RHOA,CTNNAL1,FMN1,SYBU,STMN3,DIAPH2,AIF1L,SNTB1,KIF11,SKA1,MAPK8IP1,ABLIM2,MAP1B,KLHL2,PROM1,PKD2,CENPE |
| 1.307e-09 | -20.46 | P53_DN.V1_UP | MSigDB lists | P53_DN.V1_UP | 184 | 59 | 17758 | 2588 |
EXPH5,SUN1,LTBP1,KLK10,UGT8,IGFBP6,GRIK2,SOX9,SDC4,NDC80,IL18,GPSM2,DHRS3,HDAC9,EPCAM,CTNNBIP1,VASP,SCNN1A,CYR61,AIM1,CD9,USP1,TACSTD2,RP2,LOXL1,CDKN2D,CPE,SPRY2,SMAGP,TUBA4A,LAMP3,OLFML2A,ENPP4,CORO2A,PTPRH,RNF11,FHL2,YES1,MEST,LHFPL2,EGFR,BCL10,BCAR3,LRRC42,FYN,AREG,SCG2,COL13A1,PTK7,AXL,LRIG1,SPINT2,SERPINB5,ZNF165,KLF5,MAP3K5,MAFF,AHR,IRF1 |
| 1.360e-09 | -20.42 | death | biological process | GO:0016265 | 1112 | 238 | 16441 | 2455 |
LAMP1,CASP3,ADD1,GRIK2,RET,SUDS3,XIAP,CUL1,UBE2Z,PSME1,SEPT4,SH3KBP1,TP73,DAPK2,PAK6,RPS6KA2,PSMD1,CTNNB1,CTGF,ELMO2,SIVA1,PSMC2,TNFRSF18,TIAM1,XKR8,CYP1B1,KCNIP3,ACVR1C,ITCH,CASP9,BNIP3L,KLK6,EAF2,STK17B,CDK1,POR,VCP,ABR,OPTN,SGPP1,TNS4,SLC25A4,DNM1L,TBX1,MADD,MAP3K11,KLF11,UNC5B,ARF6,TRAF5,RTN3,PSMC1,FGD1,BMF,PSMD7,SLC25A27,NOTCH2,NCKAP1,PHLPP1,TNFRSF19,ADAMTSL4,LMNA,MECOM,TFAP4,RB1,CYR61,PAK2,MSH2,DAPK1,MAP3K9,FNIP1,SELK,TNFRSF12A,CD70,BRAT1,MYDGF,PIM1,NTN1,WNT3A,PSMA5,PRODH,PTPRH,SHARPIN,ERO1A,PYGL,SCRIB,PKM,CYFIP2,BCL2L13,DPYSL4,PSMA4,FBXO10,RHOB,G2E3,FAS,STK17A,FNTA,H1F0,HTT,NFKBIA,ITPR1,MAP3K5,SEMA3A,IFI6,RPS6KA3,TMEM173,DMPK,XDH,IRF1,RAD21,INPP5D,RPS6KA1,PSME2,SOD2,TP53,P2RX7,BLCAP,BCL2L1,AIFM2,PHLDA1,EMP2,BCAP31,TNFSF9,ZNF385B,ARHGEF16,IER3,CDH1,RALB,CDKN1B,DAB2IP,STEAP3,APIP,EGLN3,SCN2A,CDKN2D,F2R,ATG4D,EBAG9,MX1,PPIF,SIRT1,SLC5A11,EVA1A,RFK,AKT1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CD40,CASP4,JADE1,DNAJC10,NGFRAP1,STK26,PSMD3,STAT1,EFNA5,MLKL,ARHGAP4,AREL1,AIFM3,ZMAT1,GCLM,ARHGEF3,TAOK2,NKX3-1,SORT1,ARHGEF11,CKAP2,DAP,TRAF2,ARHGEF7,SERPINB9,RASSF7,BIK,PSMD10,TGFBR1,JAG2,PKN1,BEX2,SGPL1,TOP2A,PDCD10,CARD8,ADORA1,CTSC,PTEN,MCF2L,CST3,BAX,DRAM1,SGK1,PLEKHF1,TMBIM6,ADAM15,KANK2,BUB1,ERBB3,ERCC2,MAP3K7,RAG1,FAIM,MSH6,P2RX4,RHOA,PLSCR1,PSMB4,GCLC,PLAUR,PIK3R1,LITAF,PARP4,EMP3,TRIM35,PIM3,BCL10,CTSL,CASP7,KIAA0141,TRIM69,FGFR2,PRDX3,CTSV,E2F1,UACA,ARRB1,ITGAV,GPER1,FZD5,ARHGEF9,ESPL1,HIPK3,AHR,OCLN,MELK,ARHGEF4,NGEF |
| 1.360e-09 | -20.42 | cell death | biological process | GO:0008219 | 1112 | 238 | 16441 | 2455 |
LAMP1,CASP3,ADD1,GRIK2,RET,SUDS3,XIAP,CUL1,UBE2Z,PSME1,SEPT4,SH3KBP1,TP73,DAPK2,PAK6,RPS6KA2,PSMD1,CTNNB1,CTGF,ELMO2,SIVA1,PSMC2,TNFRSF18,TIAM1,XKR8,CYP1B1,KCNIP3,ACVR1C,ITCH,CASP9,BNIP3L,KLK6,EAF2,STK17B,CDK1,POR,VCP,ABR,OPTN,SGPP1,TNS4,SLC25A4,DNM1L,TBX1,MADD,MAP3K11,KLF11,UNC5B,ARF6,TRAF5,RTN3,PSMC1,FGD1,BMF,PSMD7,SLC25A27,NOTCH2,NCKAP1,PHLPP1,TNFRSF19,ADAMTSL4,LMNA,MECOM,TFAP4,RB1,CYR61,PAK2,MSH2,DAPK1,MAP3K9,FNIP1,SELK,TNFRSF12A,CD70,BRAT1,MYDGF,PIM1,NTN1,WNT3A,PSMA5,PRODH,PTPRH,SHARPIN,ERO1A,PYGL,SCRIB,PKM,CYFIP2,BCL2L13,DPYSL4,PSMA4,FBXO10,RHOB,G2E3,FAS,STK17A,FNTA,H1F0,HTT,NFKBIA,ITPR1,MAP3K5,SEMA3A,IFI6,RPS6KA3,TMEM173,DMPK,XDH,IRF1,RAD21,INPP5D,RPS6KA1,PSME2,SOD2,TP53,P2RX7,BLCAP,BCL2L1,AIFM2,PHLDA1,EMP2,BCAP31,TNFSF9,ZNF385B,ARHGEF16,IER3,CDH1,RALB,CDKN1B,DAB2IP,STEAP3,APIP,EGLN3,SCN2A,CDKN2D,F2R,ATG4D,EBAG9,MX1,PPIF,SIRT1,SLC5A11,EVA1A,RFK,AKT1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CD40,CASP4,JADE1,DNAJC10,NGFRAP1,STK26,PSMD3,STAT1,EFNA5,MLKL,ARHGAP4,AREL1,AIFM3,ZMAT1,GCLM,ARHGEF3,TAOK2,NKX3-1,SORT1,ARHGEF11,CKAP2,DAP,TRAF2,ARHGEF7,SERPINB9,RASSF7,BIK,PSMD10,TGFBR1,JAG2,PKN1,BEX2,SGPL1,TOP2A,PDCD10,CARD8,ADORA1,CTSC,PTEN,MCF2L,CST3,BAX,DRAM1,SGK1,PLEKHF1,TMBIM6,ADAM15,KANK2,BUB1,ERBB3,ERCC2,MAP3K7,RAG1,FAIM,MSH6,P2RX4,RHOA,PLSCR1,PSMB4,GCLC,PLAUR,PIK3R1,LITAF,PARP4,EMP3,TRIM35,PIM3,BCL10,CTSL,CASP7,KIAA0141,TRIM69,FGFR2,PRDX3,CTSV,E2F1,UACA,ARRB1,ITGAV,GPER1,FZD5,ARHGEF9,ESPL1,HIPK3,AHR,OCLN,MELK,ARHGEF4,NGEF |
| 1.428e-09 | -20.37 | cell part morphogenesis | biological process | GO:0032990 | 967 | 212 | 16441 | 2455 |
MYL9,EMX1,CFAP74,UGT8,AGRN,AK7,EPHA4,CCNO,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,WEE1,PSMD1,RPS6KA2,LRRC6,SHC3,DPYSL2,PSMC2,DLG1,DNM2,TRPC1,NTN4,MYH14,CTTN,PACSIN1,BTBD3,TIAM1,RASGRP1,DNAAF3,ATL1,SPEF2,CELSR2,FOPNL,RNF165,EZR,ULK2,DPYSL3,DZIP1L,PLCG1,MAP2,DNM1L,LIMK1,TRAF3IP1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,RAB23,PSMD7,CALM3,DUSP5,SSX2IP,RAC2,VASP,IGF1R,LRRN2,OCRL,FLRT3,PAK2,COL6A1,CACNA1D,NCAM1,WNT3A,NTN1,TTLL1,PSMA5,DNAI1,DPYSL5,B9D2,RGMB,CEP89,CALM1,KIF20B,EPHA1,ILK,NPHP3,DPYSL4,RANBP9,PSMA4,NFIB,EGFR,RASA1,RHOB,CDK5R1,ONECUT1,PVRL2,SEMA4D,MATN2,WDR19,AURKA,PITPNA,NR4A2,EFNA1,B4GAT1,ARPC2,CFAP20,TRPC3,JAK3,SEMA3A,RPS6KA3,KLF7,EHD1,SPRED1,MTM1,TCTN2,PSME2,RPS6KA1,IQGAP1,C5orf30,ERBB2,RASGRP3,ZMYND10,BCL2L1,STIL,PDGFA,TTC21B,ARTN,DACT1,DAB2IP,EPHB4,RASGEF1A,DLG3,SNX10,ETV4,FRS3,SEMA3B,COL6A2,PRKCQ,SLC11A2,ALCAM,MYL12A,DAG1,CEP162,ARHGAP35,EPHA10,IRS2,FYN,JAK1,PSMD3,SLC9A6,WWTR1,NRG1,EFNA5,SPTBN5,PLXND1,LIFR,COBL,ATMIN,TTC8,COL9A3,PACSIN2,FARP1,ARHGEF11,POC1B,ARHGEF7,LRP4,FLOT1,PSMD10,NES,COL4A5,PLPPR4,FGF19,EFNB1,NRP2,ITGA2B,RND1,GBX2,NEO1,KIF5B,ANK1,PTEN,BMP7,BAX,SGK1,ERBB3,RPGR,CAMK2G,S100A6,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,FMN1,CFAP46,RAPGEF2,GRIN1,RAB3IP,YES1,BBS2,SPAG1,ABLIM2,MAP1B,CNTNAP1,FGFR2,FGF18,PGRMC1,NR4A3,RYK,GRIN2D,ITGAV,CEP41,L1CAM,RGMA,NGEF |
| 1.476e-09 | -20.33 | protein metabolic process | biological process | GO:0019538 | 4189 | 746 | 16441 | 2455 |
KLK10,TRIM24,ADD1,MRPS15,TRIM5,DNAJC3,HEXB,RET,XIAP,FBXO2,NRG2,IL18,MORF4L2,DPP8,BARD1,SPSB1,GRM5,CALM2,DAPK2,WEE1,PSMD1,TGFBR3,MUC4,UBE2T,FUT1,CRY2,PPP1CA,TINAGL1,PIK3CD,TIPARP,CPE,MGAT5,ERAP2,TUBA4A,NEK4,FBXL16,TNIP1,RNF11,MTRF1L,KDELR3,LOXL2,F12,ICMT,RNF19B,ARF4,PIAS3,LIMK1,MYLK,NOD2,MAP3K11,HDAC1,MRPS28,RNASEL,ITPKA,GAB1,GGA1,NUAK1,SEC61G,SOX9,ZNRF3,MERTK,LMNA,RABGGTA,ATG4A,MARCH8,DNPEP,FBXO7,NEK2,FBXL14,PCYOX1,MAP3K9,USP38,USP1,ALPK1,STT3B,MYDGF,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,TTLL1,PPP6R1,NAGPA,UFD1L,MAPKAPK3,STAT4,ERO1A,SHARPIN,ELK1,ILK,TP53INP2,PSMA4,STK17A,PTPRF,NCOA3,FNTA,MTFMT,TIMM8A,SETD3,TEX30,AURKA,STK39,B4GAT1,ALG2,CFAP20,NUP58,RPS6KA3,RUSC1,XDH,ADAMTS16,EGLN1,DMPK,MTM1,TUBB4B,GALNT12,INPP5D,RHBDL3,PTTG1,WDTC1,TESK2,PRSS22,MAPK4,GRK6,MVB12B,PRKACA,MOCS1,CCND1,MUC16,RNF220,SP100,XYLT2,RASGEF1A,RNF169,SSH3,SEC61B,ERMP1,RIPK2,PTPN9,VPS4B,PXYLP1,XRCC6BP1,IRS2,CDK19,WFS1,AXL,WWTR1,TRABD2A,MAPK12,NKX3-1,TAOK2,HSP90B1,MAN1A2,BACE1,DCAF7,TRAF2,CCM2,SDC4,PDIA3,CTSZ,PKN1,TSPAN17,DTX3L,CAPN2,FUT2,IRAK1,CTSC,ARSG,GPC3,ALG13,MGAT4A,CST3,BAX,ADAM15,WWP1,IGFBP2,MAPK11,RAG1,CRTAP,ADAMTS2,RAPGEF2,PIK3R1,DUSP23,EIF5A2,NUB1,GRIN1,UBE2A,PIM3,NEURL1B,TXK,GALNT3,DCAF10,BTG1,LDLRAP1,RPL12,PLOD2,ATXN7L3,ACVRL1,DBI,PPM1H,ITGAV,NUP37,WDR45B,PHC1,TLL2,UNKL,TNK1,TRIM2,AGRN,PPM1J,CUL4B,EPHA4,SUDS3,LMCD1,DNAJB11,MGAT5B,HDAC6,PDGFB,SDC1,PIGL,SPTB,NUP210,RPS6KA2,SHC3,P4HB,MKRN3,PSMC2,PASK,DUSP10,TRAM1,PLK1,CD55,MARK1,PTPN18,C12orf65,CR2,ERP44,KLK6,PRKRA,CDK1,VCP,KDM4D,TRIM9,HS6ST1,MSL1,WIPI1,P4HA2,DOLPP1,TTC9,POMT1,HS6ST3,PRKAA2,PRSS8,LMTK3,DNAJB2,RASA2,UBASH3B,PSMD7,ADCK5,RAB6A,B4GALT4,FBLN1,PGAP1,B4GALNT1,BMP2,UBE2Q2,IGF1R,PAK2,TBCD,SLC30A6,EXOC8,MDFIC,PIM1,CKAP4,PSMA5,CHSY3,MRPS33,USP31,TESK1,MGAT4B,KBTBD8,STRADB,EIF2AK1,PDK3,BCL2L13,ZDHHC3,G2E3,NMT2,CDK5R1,MAPKAPK2,OTUD6B,PHLPP2,KBTBD2,P4HA3,ZDHHC7,CTBP1,RNF146,USP43,RAD21,P3H2,XYLT1,CTDSPL,P2RX7,ERBB2,RASGRP3,KBTBD11,PER2,CDK14,RAD23A,PDGFA,KMT5C,PPME1,ZDHHC23,PLK4,NOTCH3,LMAN1,EGLN3,CTDSP2,SULF2,CTH,CPD,SIRT1,PPIF,ERLEC1,TCEB2,AKT1,CDC20,PTGER4,DAG1,DNAJC10,PTPRJ,IDE,ATP1A1,MMP17,PSMD3,PTK7,STK38,ADAMTS14,CHMP4B,IRF7,RPL22,LTA4H,ST3GAL1,POMGNT2,NDST3,ZC3HC1,CTDSP1,MAN2B2,CMAS,PINK1,DYRK3,CPEB4,TRAPPC10,TAB3,KLHL13,DAP,CTSB,GNE,PSMD10,JAG2,DSE,AIP,DNAJB9,PPP2R3A,ZDHHC21,CDK16,UBE2J1,SGK1,TRIM21,BUB1,SYK,CAMK2G,GCNT1,DUSP1,MLEC,PSMB4,AMFR,PLAUR,PPARA,DPP9,COL7A1,CAPNS1,GGH,PELI3,RNPEP,MAPK8IP1,SCRN2,BCL10,USP6,PRDX4,FUCA1,SERPINA1,SCG2,FGF18,SPCS3,NDFIP1,UBE2C,HIPK3,ACVR1,SSH1,HSPG2,CUL1,PSME1,NANS,CAMK1D,CCNB1,PJA2,PICK1,ASPHD2,PAK6,IL31RA,PALD1,PIK3CA,MARCH2,TFG,METAP2,SPATA18,ACVR1C,PBK,CDYL,CASP9,BNIP3L,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,POR,ULK2,SGPP1,AREG,PLK2,GNPTAB,SH2D3C,PPP2R4,PRDM5,BMP1,EIF4EBP2,MAPK13,TRAF5,MRPL44,CDK17,DHPS,PRKAA1,NOTCH2,HERC6,TNFRSF19,BMP2K,SH3RF2,CALR,ZNRF2,NECAB3,RPL39,PPP4R1,PRKG1,OPN3,ADCK2,DAPK1,TPST1,SORL1,CTSD,MAST4,TSPAN33,EEF1D,TMED2,TRAK2,SOCS5,PIGC,GFPT1,B3GNT7,PMPCB,DDB2,KLK5,MMD,PRSS23,CALM1,PTPRH,WHSC1,EPHA1,CYFIP2,KDM3A,JADE2,FBXO10,RASA1,FAS,MMP15,PRKAG2,PELI2,CSNK1G1,ZDHHC20,PIAS2,AGBL5,KLK7,CDK18,MAP3K5,IFIH1,NRBP1,ELK4,SPRED1,CAPN12,DLGAP5,ST14,RPS6KA1,SUZ12,RNF182,DDR1,FLT3,TMPRSS4,ART5,EPM2A,ZFYVE9,CD46,DOK4,FICD,CDKN1B,DAB2IP,EPHB4,PHKA2,LGMN,ATG4D,SEC23A,CAPN6,PRKCQ,SLC11A2,PKMYT1,ASB13,CBL,B3GALNT2,ZMPSTE24,EPHA10,AMZ2,FYN,DDOST,JAK1,STK26,NGFRAP1,KIAA1804,TRIOBP,PPP1CB,NRG1,MLKL,HS3ST3B1,B4GALT3,AREL1,MRPS9,OTUD5,PCOLCE,IGFBP6,CDCA3,CBLL1,HERC5,FBXO6,FGF19,WWP2,RNF128,MGAT1,PTEN,FUT8,SGK3,ERCC2,ERBB3,MAP3K7,TRIM62,NCOA2,RASGRF1,B3GNT2,CASK,LONRF3,FURIN,PARP4,FBXO9,C1GALT1C1,UBAC1,YES1,FOS,ARSK,CRTC2,FGFR2,PRDX3,RYK,ERAP1,GRIN2D,LRRK1,ARSB,CPEB2,ESPL1,MELK,USP16,CCNC,CASP3,FAF2,CAMKK1,UBE2Z,UBE2Q1,VARS2,TAF6L,DNER,TRIM68,CHPF,ADPRHL1,CDKL5,IMPAD1,DLG1,ASH2L,PTPRE,IL1RAP,RASGRP1,STK35,TRIM8,ASXL1,LAP3,ITCH,USP18,RNF165,MRPS18A,ROR1,MRPS36,TYSND1,STK17B,ADRBK2,MAN2A2,FASTKD1,HPSE,UEVLD,IARS2,CAB39,PSMC1,PPP2R5D,CAPN1,CPPED1,PCSK5,PPP1R12A,ASB9,ASL,CALM3,TEC,PHLPP1,ADAMTSL4,DUSP5,B3GALNT1,OTUD1,FAM20C,PRKCI,SRP54,NPTN,ZRANB1,GAD1,DESI2,MDFI,GYLTL1B,FBXO8,PDIK1L,EGFR,GLCE,NUDT16,INSR,UAP1,PLPP3,DCUN1D1,ALPK3,CTSA,YOD1,JAK3,APOL2,FBXW5,LMO7,PAX6,IL15,PSME2,HDAC11,PDIA5,PHLDA1,EXT2,SAP130,SETDB2,KIF14,ZDHHC12,RPN2,ECE1,PDIA6,LOXL1,F2R,SCYL3,FRS3,SEPHS1,MAP3K3,GCA,TAF5,PTPRU,MRPS35,DUSP4,CDC25C,MAP3K6,CASP4,SOCS3,JADE1,HSF4,PEX2,CANT1,SPTBN5,ABCA1,CBX4,TSPAN15,CIT,SHPRH,JKAMP,TGFBR1,NOTUM,TRIB2,SBF1,POMGNT1,HDAC9,KIF5B,CARD8,ADRBK1,A4GALT,RRBP1,TRIM3,IQGAP3,SLC35A1,MYO5A,B3GALT6,DCAF6,ADAM17,RAB3B,CFAP46,RC3H2,RGCC,RUNX3,FOXL1,KLHL2,CTSL,CASP7,TRIM69,PRCP,CTSV,CSGALNACT1,DTX4,UBE2D2,TADA2B,ARRB1,OTUB2,GLB1,PLOD3,CEP41,ABCG1 |
| 1.491e-09 | -20.32 | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | 158 | 53 | 17758 | 2588 |
CASP3,DLGAP5,TUBB4B,CIT,CDCA3,KIF23,RACGAP1,KIF2C,CCNB1,SSX2IP,CKAP5,TOP2A,CDKN2C,FAM111A,FLII,CCNA2,UBE2T,STIM1,ARL1,PRC1,NEK2,PLK4,CKS1B,KIF22,BUB1,PPP1CA,SMC4,CKS2,HMMR,HES1,CENPA,KIF20A,CDC20,CRIP2,NUSAP1,AURKB,ANLN,CDC25C,CDK1,ABR,IDE,RBL1,HTT,CDCA5,AURKA,KPNA2,CENPE,SGOL1,UBE2C,CCNB2,CBX5,E2F8,MELK |
| 1.546e-09 | -20.29 | endoplasmic reticulum part | cellular component | GO:0044432 | 1114 | 235 | 17570 | 2579 |
UNC93B1,FAF2,IL15RA,PNPLA2,DNAJC3,TAP1,DNAJB11,ITPR2,CDIPT,PJA2,PDGFB,PIGL,ERP29,ABCD4,CYP1A1,NUP210,STIM1,P4HB,OSBPL3,CYP2S1,LMAN2L,RDH14,DLG1,MARCH2,TECR,SCARA3,TRAM1,RASGRP1,ERAP2,CERS2,CYP1B1,ATL1,NFE2L1,KDELR3,ERP44,ESYT1,ICMT,MCFD2,PTGFRN,CYP4F3,POR,RAB2B,VCP,RHEB,COL12A1,SGPP1,KDSR,AGPAT2,AREG,P4HA2,DOLPP1,SARAF,PIEZO1,TTC9,POMT1,RTN3,SEC61G,CYP2J2,FXYD3,HLA-E,HLA-F,ELOVL7,NOTCH2,ADAMTSL4,DHRS3,PGAP1,CALR,CES2,NECAB3,FLRT3,COL6A1,SUCO,SELK,STT3B,HLA-C,MYDGF,FAR2,MOXD1,WNT3A,ALDH3A2,CKAP4,TMED2,EPHX1,KDELR1,FAM69A,CYP26B1,PIGC,FADS2,UFD1L,LPGAT1,ERO1A,EMC2,MEST,SPTLC2,EGFR,CYB5A,MOSPD3,FA2H,COL13A1,FAAH,PLPP3,MFSD2A,P4HA3,ITPR1,DGAT2,SAMD8,PLD1,ALG2,MAP3K5,COL16A1,APOL2,TMEM173,DRD1,DMPK,PLA2G4A,P3H2,CERCAM,XYLT1,APOO,PDIA5,COL18A1,MGST2,LPIN3,FLT3,CYP39A1,BCAP31,KTN1,EXT2,CYP26A1,CDS1,RCN1,PDGFA,CYP4F11,XYLT2,REEP1,RPN2,NOTCH3,ACSL4,OSBPL7,MINPP1,LMAN1,PDIA6,MX1,SOAT1,SEC23A,SEC61B,ERLEC1,ERMP1,COL6A2,EVA1A,TMEM43,SYNE2,C3orf52,CLSTN1,PKMYT1,DNAJB14,ITPR3,TMTC2,TRIQK,ATP10D,CASP4,ZMPSTE24,TAPBP,DNAJC10,PTGS2,DDOST,WFS1,SLC9A6,PNPLA6,CANT1,CYP2U1,REEP4,NR3C2,POMGNT2,KDELC2,FAM134B,COL9A3,CDS2,SORT1,HSP90B1,BACE1,JKAMP,SCD5,TRAF2,PDIA3,CTSZ,PLD2,COL4A5,FBXO6,LBR,DNAJB9,HLA-A,SGPL1,PDIA4,CAPN2,CTSC,ARSG,ALG13,RRBP1,BAX,UBE2J1,SGK1,TMBIM6,CNPY3,CAMK2G,TMX1,CRTAP,PDGFC,MLEC,RHOA,AMFR,PLAUR,PIK3R1,EIF5A2,ELOVL3,FURIN,COL7A1,CARD19,ARSK,TXNDC11,MAPK8IP1,HLA-B,SERPINA1,PLOD2,DBI,PGRMC1,ERAP1,PKD2,GPER1,SPCS3,PLOD3,ARSB,PTGES,ESYT2,ABCG1 |
| 1.637e-09 | -20.23 | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN | MSigDB lists | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN | 52 | 26 | 17758 | 2588 |
HJURP,SPC25,KIF20A,JKAMP,CDCA8,MORC4,KIF20B,CDCA2,KIF2C,POLD3,KIF11,MNS1,CENPN,MESDC2,ENDOD1,CDKN2C,E2F7,PDLIM3,ZNF367,CDCA7L,FAM83D,AURKA,DONSON,MYBL1,MED30,MELK |
| 1.747e-09 | -20.17 | Signalling by NGF | REACTOME pathways | R-HSA-166520 | 430 | 111 | 8202 | 1235 |
CASP3,SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,ARHGEF16,CALM2,PDGFA,PSMD1,RPS6KA2,RALB,SHC3,PSMC2,PIK3CA,DNM2,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,TIAM1,RASGRP1,FRS3,RIPK2,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,ABR,IRS2,PLCG1,FYN,PPP2R5A,JAK1,NGFRAP1,PSMD3,MAP3K11,HDAC1,MAPK13,NRG1,SPTBN5,ARHGAP4,PSMC1,GAB1,PPP2R5D,PRKAR1A,MAPK12,FGD1,PCSK5,TNRC6C,ARHGEF3,ARHGEF11,RASA2,ARHGEF7,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,IRAK1,ADRBK1,PTEN,MCF2L,PRKCI,MAPK11,ERBB3,NCAM1,MAPK7,PSMA5,CAMK2G,DUSP1,RASGRF1,ADAM17,RHOA,PSMB4,MAPKAPK3,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,FURIN,ELK1,PSMA4,RASA1,EGFR,MAPKAPK2,FGFR2,PHLPP2,FGF18,ITPR1,NFKBIA,ARRB1,GRIN2D,JAK3,ARHGEF9,RPS6KA3,ARHGEF4,NGEF |
| 2.048e-09 | -20.01 | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP | 195 | 61 | 17758 | 2588 |
ARHGAP11A,SPC25,DLGAP5,HJURP,TUBB4B,CIT,CDCA3,NDC80,ERCC6L,KIF23,NDUFA4,NUF2,MGST2,STIL,MNS1,CENPN,NRP2,TOP2A,CCNA2,SIVA1,ARL1,GALNS,BDH1,ELF5,NEK2,PLK4,CKS1B,KIF22,BUB1,MXD3,STT3B,SCN2A,C12orf75,CKS2,CENPA,KIF20A,FIGNL1,ASPM,CKAP2L,VWA1,TCF7,NUSAP1,KIF20B,AURKB,PIF1,PKMYT1,CCNF,SKA1,ETS2,RCBTB2,NEIL3,CDCA5,DBI,FAM110C,KPNA2,CENPE,NCAPG2,CCNB2,ESPL1,E2F8,MELK |
| 2.238e-09 | -19.92 | ELVIDGE_HYPOXIA_UP | MSigDB lists | ELVIDGE_HYPOXIA_UP | 164 | 54 | 17758 | 2588 |
ENO2,ZNF395,NDRG1,SOX9,PDGFRL,GDF15,PDGFB,PHLDA1,DDR1,S100A2,PGAP1,ELF3,SRPX,ARTN,CYR61,DPYSL2,OPN3,SORL1,GYS1,LIMCH1,ECE1,PIM1,EGLN3,CITED2,LOXL1,TIPARP,S100A6,CYP1B1,DUSP1,OLFML2A,QSOX1,PGM1,NR3C1,S100A4,PLAUR,SAT1,BNIP3L,AK4,LOXL2,KDM3A,DPYSL4,FOS,EGFR,CYB5A,SLCO4A1,FYN,P4HA2,ITPR1,CSGALNACT1,MAFF,CSRP2,KLF7,EGLN1,RRAGD |
| 2.256e-09 | -19.91 | HALLMARK_ESTROGEN_RESPONSE_EARLY | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_EARLY | 200 | 62 | 17758 | 2588 |
FARP1,KLK10,PAPSS2,CALB2,BLVRB,RET,EGR3,SLC7A2,PLA2G16,DHRS3,ELF3,IL17RB,CCND1,ADD3,SCNN1A,RPS6KA2,MLPH,IGF1R,KCNK5,IL6ST,REEP1,OPN3,FAM63A,FAM102A,MYBL1,SULT2B1,MAST4,TIPARP,TIAM1,RASGRP1,SEMA3B,CYP26B1,PPIF,HES1,SLC37A1,CELSR2,PRSS23,MICB,AMFR,SYBU,FHL2,TFAP2C,ASB13,FOS,SEC14L2,ENDOD1,TMEM164,ALDH3B1,PDLIM3,TJP3,AREG,DHRS2,WFS1,LRIG1,RAB31,CANT1,ANXA9,GLA,CHPT1,PTGES,TOB1,FAM134B |
| 2.287e-09 | -19.90 | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | 261 | 75 | 17758 | 2588 |
GRHL2,ST14,HDAC11,FHDC1,GATA3,SDC1,DDR1,EPCAM,SESN3,CDH1,ELF5,CAPG,BCL6,POF1B,CLDN4,KIF22,TACSTD2,EPB41L4B,NFKB2,F2R,TUBA4A,MARK1,SAT1,EZR,TFAP2C,PLEKHB1,IRX3,DPYSL3,MDK,PIAS3,ATP1A1,AREG,KCNK1,SHROOM3,NGFRAP1,PLK2,ZNF704,RPL22,FAM134B,ARHGEF3,IGFBP6,ESRP1,FXYD3,SDC4,SOX9,CYB561,ISYNA1,ANO1,FZD6,SPP1,TIMP1,RNF128,IRAK1,VASN,CALD1,CD9,SLC44A2,ACTA2,IGFBP2,TNFRSF12A,ERBB3,TTPA,TGIF1,COL7A1,FOS,GALNT3,PROM1,FGFR2,RND3,SPINT2,SERPINB5,COL16A1,OCLN,FOXA1,PROM2 |
| 2.356e-09 | -19.87 | MODULE_180 | MSigDB lists | MODULE_180 | 109 | 41 | 17758 | 2588 |
BCAM,BLVRB,GATA3,CRABP2,PDGFB,ARHGEF16,SYTL2,CDS1,ELF3,IL17RB,EPCAM,SCNN1A,NUP210,MLPH,KIAA1107,CDH1,LLGL2,METTL7A,BMP7,BDH1,CD9,CLDN4,ERBB3,SULT2B1,DPYSL5,SSH3,KIAA0040,TFAP2C,AIF1L,CYB5A,RHOB,MDK,TJP3,NAT1,SPINT2,MAL2,ANXA9,HOOK1,ISOC1,OCLN,FOXA1 |
| 2.358e-09 | -19.87 | non_seminoma | COSMIC cancer mutations | non_seminoma | 505 | 123 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,FLT3,DDR1,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PLK4,EPHB4,SCYL3,STK35,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,CBL,MAP3K6,ADRBK2,STK17B,ULK2,EPHA10,FYN,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MYLK,KIAA1804,MAP3K11,MAPK13,RNASEL,MLKL,FAM134B,MAPK12,PRKAA2,PINK1,DYRK3,TAOK2,CDK17,PRKAA1,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,IGF1R,IRAK1,ADRBK1,CDK16,PTEN,NEK2,DAPK1,SGK3,PRKCI,MAP3K9,ADCK2,PRKG1,FNIP1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MAPK7,MAP3K7,SYK,PHKG2,CAMK2G,CASK,ADCK3,TESK1,DCHS1,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,EGFR,BSDC1,TXK,STK17A,MAPKAPK2,INSR,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,RPS6KA3,MELK,DMPK,GOLGB1 |
| 2.463e-09 | -19.82 | PH | pfam domains | PF00169 | 177 | 58 | 16629 | 2504 |
PLEKHG3,ARAP3,FARP1,PLEKHJ1,ARHGEF7,CIT,RASA2,TEC,SBF1,PHLPP1,DOCK11,ARHGEF16,SNTA1,ACAP2,ARHGAP42,ADRBK1,RALGPS2,MCF2L,DNM2,PLEKHF1,CADPS2,RTKN2,TIAM1,FARP2,RASGRF1,ARAP2,PLEKHA6,AKT1,PHLDB3,PLEKHO1,PLEKHA7,SPATA13,FAM109A,SNTB1,ANLN,ADRBK2,ABR,PLEKHB1,RASA1,ARHGAP24,IRS2,DGKH,SWAP70,PLEKHH2,MPRIP,TRIOBP,ARAP1,APPL2,FGD6,PLD1,AFAP1,GAB1,ARHGEF9,DEF6,NGEF,DOCK9,ARHGEF4,FGD1 |
| 2.507e-09 | -19.80 | programmed cell death | biological process | GO:0012501 | 1074 | 230 | 16441 | 2455 |
LAMP1,CASP3,ADD1,GRIK2,RET,SUDS3,XIAP,CUL1,UBE2Z,PSME1,SEPT4,SH3KBP1,TP73,DAPK2,PAK6,RPS6KA2,PSMD1,CTNNB1,CTGF,ELMO2,SIVA1,PSMC2,TNFRSF18,TIAM1,XKR8,CYP1B1,KCNIP3,ACVR1C,ITCH,CASP9,BNIP3L,EAF2,STK17B,CDK1,POR,VCP,ABR,SGPP1,TNS4,SLC25A4,DNM1L,TBX1,MADD,KLF11,UNC5B,ARF6,TRAF5,RTN3,PSMC1,FGD1,BMF,PSMD7,NOTCH2,NCKAP1,PHLPP1,TNFRSF19,ADAMTSL4,LMNA,MECOM,TFAP4,RB1,CYR61,PAK2,MSH2,DAPK1,MAP3K9,FNIP1,SELK,TNFRSF12A,CD70,BRAT1,MYDGF,PIM1,NTN1,WNT3A,PSMA5,PRODH,PTPRH,SHARPIN,ERO1A,PYGL,SCRIB,PKM,CYFIP2,BCL2L13,PSMA4,FBXO10,RHOB,G2E3,FAS,STK17A,FNTA,H1F0,HTT,NFKBIA,ITPR1,MAP3K5,SEMA3A,IFI6,RPS6KA3,TMEM173,DMPK,XDH,IRF1,RAD21,INPP5D,RPS6KA1,PSME2,SOD2,TP53,P2RX7,BLCAP,BCL2L1,AIFM2,PHLDA1,BCAP31,TNFSF9,ZNF385B,ARHGEF16,IER3,CDH1,RALB,CDKN1B,DAB2IP,STEAP3,APIP,EGLN3,SCN2A,CDKN2D,F2R,ATG4D,EBAG9,MX1,SIRT1,PPIF,SLC5A11,EVA1A,RFK,AKT1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CD40,CASP4,JADE1,DNAJC10,NGFRAP1,STK26,PSMD3,STAT1,EFNA5,MLKL,ARHGAP4,AREL1,AIFM3,ZMAT1,GCLM,ARHGEF3,TAOK2,NKX3-1,SORT1,ARHGEF11,CKAP2,DAP,TRAF2,ARHGEF7,SERPINB9,RASSF7,BIK,PSMD10,TGFBR1,JAG2,PKN1,BEX2,SGPL1,TOP2A,PDCD10,CARD8,ADORA1,CTSC,PTEN,MCF2L,CST3,BAX,DRAM1,SGK1,PLEKHF1,TMBIM6,ADAM15,KANK2,BUB1,ERBB3,ERCC2,MAP3K7,RAG1,FAIM,MSH6,P2RX4,RHOA,PLSCR1,PSMB4,GCLC,PLAUR,PIK3R1,LITAF,TRIM35,PIM3,BCL10,CTSL,CASP7,KIAA0141,TRIM69,FGFR2,PRDX3,CTSV,E2F1,UACA,ARRB1,ITGAV,GPER1,FZD5,ARHGEF9,ESPL1,HIPK3,AHR,OCLN,MELK,ARHGEF4,NGEF |
| 2.521e-09 | -19.80 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | 147 | 50 | 17758 | 2588 |
KLF2,GALK1,LASP1,TM2D2,AVPI1,AGRN,PAPSS2,DAP,PNPLA2,ASAH1,PKP2,FAM101B,MAP1LC3B,SLC35E4,WWP2,ATP6V0B,CTGF,CAPG,CD9,FXYD5,TRAM1,SNX10,S100A13,TMBIM1,RBMS2,ABCC1,DUSP1,RHOA,ALDH2,PQLC3,PRSS23,TMEM43,FHL2,NFE2L1,UTRN,EMP3,SNAPC2,PNKD,C3orf58,CARHSP1,TRIM47,TIMP3,STAT6,SERPINB6,FHL1,TMEM159,TOB1,ACOT7,ANXA11,FAM134B |
| 2.549e-09 | -19.79 | positive regulation of kinase activity | biological process | GO:0033674 | 619 | 147 | 16441 | 2455 |
CCNC,TXN,CAMKK1,EPHA4,NRG2,PSME1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,PAK6,PSMD1,SHC3,PSMC2,PIK3CA,DLG1,RASGRP1,NEK4,SOD1,PRKAR2B,CDK1,PLCG1,GPRC5B,MADD,NOD2,MAP3K11,CAB39,PSMC1,GAB1,PIFO,RASA2,PRKAA1,PSMD7,CALM3,DUSP5,BMP2,CYR61,PAK2,MAP3K9,MDFIC,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,MMD,MAPKAPK3,CALM1,STRADB,PDE5A,ILK,PSMA4,EGFR,CDK5R1,RASA1,MAPKAPK2,PRKAG2,INSR,CSF1,STK39,EFNA1,MAP3K5,JAK3,SPRED1,AVPI1,IQGAP1,PSME2,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,EMP2,STIL,FLT3,PDGFA,CCND1,RALB,KIF14,DAB2IP,RASGEF1A,F2R,HSPA2,DVL2,FRS3,MAP3K3,SIRT1,PSRC1,AKT1,RIPK2,PFKFB2,FZD4,CD40,MAP3K6,IRS2,FYN,JAK1,STK26,PSMD3,KIAA1804,SLC27A1,NRG1,SPTBN5,EFNA5,PRKAR1A,NKX3-1,TAOK2,PINK1,TAB3,TRAF2,SDC4,PSMD10,TGFBR1,PKN1,FGF19,PDCD10,IRAK1,ADORA1,BAX,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,GRIN1,RGCC,FGFR2,FGF18,ARRB1,PKD2,GRIN2D,PPP2R3C,CENPE,FZD5,CD81 |
| 2.581e-09 | -19.78 | protein serine/threonine kinase activity | molecular function | GO:0004674 | 439 | 112 | 16491 | 2452 |
LTBP1,ACVR1,CAMKK1,RPS6KA1,TESK2,MAPK4,GRK6,CAMK1D,PRKACA,CDK14,DAPK2,PAK6,TGFBR3,RPS6KA2,CDKL5,PASK,PIK3CA,PLK4,PHKA2,STK35,PLK1,MAP3K3,NEK4,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,AURKB,PKMYT1,XRCC6BP1,MAP3K6,STK17B,CDK1,ADRBK2,ULK2,STK26,CDK19,LIMK1,STK38,PLK2,MYLK,MAP3K11,KIAA1804,MAPK13,MLKL,ITPKA,MAPK12,PRKAA2,DYRK3,LMTK3,PINK1,TAOK2,CDK17,NUAK1,CIT,PRKAA1,ADCK5,TGFBR1,PKN1,BMP2K,IRAK1,ADRBK1,FAM20C,CDK16,PAK2,DAPK1,MAP3K9,PRKG1,ADCK2,PRKCI,NEK2,SGK3,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERCC2,MAP3K7,MAPK7,MAST4,SYK,PHKG2,CAMK2G,CASK,MAPKAPK3,TESK1,STRADB,EIF2AK1,PDK3,PIM3,ILK,PDIK1L,CDK5R1,EGFR,STK17A,MAPKAPK2,PRKAG2,ACVRL1,CSNK1G1,AURKA,ALPK3,STK39,CDK18,LRRK1,MAP3K5,HIPK3,RPS6KA3,MELK,DMPK |
| 2.630e-09 | -19.76 | anchoring junction | cellular component | GO:0070161 | 491 | 121 | 17570 | 2579 |
LMO7,SORBS1,KIAA1462,NF2,ADD1,HSPG2,FAM129B,NDRG1,IQGAP1,PKP2,SDC1,SLC9A3R2,GNB2,SH3KBP1,CD46,ZYX,CDH1,CTNNB1,P4HB,DLG1,DNM2,IRF2,CDH3,KIF22,DIXDC1,CTTN,TLN2,FLOT2,SMAGP,CHP1,KRT80,CAMSAP3,LAP3,SNTB2,SYNE2,EZR,TNS1,ALCAM,DAG1,LCP1,TNS4,MPRIP,JAK1,SHROOM3,CORO1C,PTK7,LIMK1,TRIOBP,PPP1CB,SPRY4,ARF6,RPL22,HSPB1,CAPN1,CD99,LASP1,FBLIM1,PACSIN2,HSP90B1,MRC2,MPZL1,PPP1R12A,ITGA6,ARHGEF7,SDC4,FLOT1,PDIA3,KIF23,SORBS3,NCKAP1,ICAM1,ITGA2B,SSX2IP,RND1,CORO1B,CALR,CAPN2,RAC2,TNS3,FLII,VASP,ITGA3,FLRT3,TBCD,CD9,ADAM15,EPB41L5,PVRL4,DCAF6,ADAM17,RHOA,CASK,FMN1,PLAUR,PLEKHA7,FHL2,SCRIB,VEZT,YES1,SNTB1,AIF1L,ILK,BCAR1,RHOB,EGFR,ARHGAP24,SCARB2,RPL12,RND3,PVRL2,PLPP3,ITGA7,ITGAV,FHL1,HMGA1,ARPC2,SHROOM2,CD81,AFAP1,L1CAM,CSRP2 |
| 2.786e-09 | -19.70 | HORIUCHI_WTAP_TARGETS_DN | MSigDB lists | HORIUCHI_WTAP_TARGETS_DN | 296 | 82 | 17758 | 2588 |
CCNC,SPC25,DLGAP5,FOXM1,PTTG1,NDC80,NUF2,KIF2C,CCNB1,CENPN,APOBEC3B,CCNA2,KIF14,AKR1B1,KIF22,TMEM64,CKS2,SEPHS1,LAMP2,PLK1,PSRC1,CENPA,PBK,CDC20,RNF11,CKAP2L,NUSAP1,CDCA2,GLO1,AURKB,ANLN,H2AFV,SLC25A5,CDK1,ZNF618,PGF,DNAJC10,PI4K2B,MPRIP,WWTR1,ARF6,BTBD6,DLAT,HJURP,DEPDC1,PPP1R2,CKAP2,CDCA3,CDCA8,KIF23,RACGAP1,LBR,TOP2A,WDFY1,PRC1,NEK2,CKS1B,USP38,BUB1,ULBP2,HMMR,RAB3B,SHMT1,KIF20A,ASPM,CRIP2,MYBL2,PIM3,KIF11,NMT2,MAP1B,FECH,FAM64A,ZDHHC20,FAM83D,AURKA,HMGA1,ARSB,CCNB2,UBE2C,ESPL1,MELK |
| 2.787e-09 | -19.70 | regulation of cell cycle | biological process | GO:0051726 | 952 | 208 | 16441 | 2455 |
CCNC,CCNI,HECA,CASP3,CUL4B,CUL1,GATA3,PSME1,CCNB1,VASH1,PLA2G16,PDGFB,BARD1,FANCI,TP73,NPM2,CALM2,SUSD2,CDKN2C,PAK6,WEE1,BTG3,CYP1A1,PSMD1,RPS6KA2,CTNNB1,CTGF,CDKL5,PSMC2,DLG1,PLK1,NEK4,AURKB,CCNF,ANLN,SESN1,CDK1,RHEB,PLK2,MADD,CAB39,HDAC1,TMEM8B,E2F8,PSMC1,MIIP,RRAGD,PRKAA2,CDK17,CDKN1C,SOX9,PRKAA1,PSMD7,CALM3,KIF23,RACGAP1,NOTCH2,MECOM,BMP2,TFAP4,CALR,RB1,IGF1R,FBXO7,PAK2,NEK2,MSH2,KNTC1,PIM1,PSMA5,CALM1,MYBL2,STRADB,SCRIB,KIF20B,SRSF5,ILK,NUBP1,PSMA4,RHOB,EGFR,CDK5R1,NUDT16,TSC1,PRKAG2,INSR,TJP3,CGREF1,CDCA5,FAM83D,AURKA,STK39,CDK18,CCNB2,CTBP1,IRF1,GAS2L1,CCNE2,DLGAP5,FOXM1,NDRG1,PSME2,CAST,CTDSPL,PTTG1,TP53,CCNL1,BCL2L1,PRKACA,STIL,PER2,CDK14,IER3,CCND1,CCNA2,DACT1,KIF14,PLK4,CDKN1B,DAB2IP,ZBTB49,CDKN2D,CTDSP2,HSPA2,CKS2,SIRT1,TIMP2,PSRC1,AKT1,FIGNL1,CDC20,VPS4B,PRKCQ,NUSAP1,RAD17,PKMYT1,CDC25C,MAP3K6,JADE1,PTGS2,CCNB3,CDK19,STK26,RBL1,PSMD3,OVOL1,CHMP4B,XRCC3,MAD2L1BP,GEN1,PRKAR1A,MAPK12,CTDSP1,BIN1,TAOK2,NKX3-1,CIT,HERC5,PSMD10,TGFBR1,ETS1,BEX2,DIRAS3,TOP2A,E2F7,PTEN,CDK16,CENPJ,BMP7,BAX,CKS1B,H2AFY,TRIM21,BRD7,BUB1,KANK2,ERCC2,HEXIM2,CITED2,DUSP1,HES1,ADAM17,ZWINT,RHOA,PSMB4,WNT10B,HMGN5,ASPM,NR4A1,RGCC,RUNX3,TRIM35,PIM3,BORA,KIF11,CDK5RAP1,FGFR2,E2F1,NR4A3,PKD2,GPER1,FHL1,CENPE,UBE2C,ESPL1,PKIA,FOXA1,USP16 |
| 2.789e-09 | -19.70 | ACCAAAG,MIR-9 | MSigDB lists | ACCAAAG,MIR-9 | 479 | 118 | 17758 | 2588 |
CCNE2,LAMP1,SLC25A24,TRIM2,FAF2,NDRG1,RET,WDTC1,UBE2Z,TESK2,UBE2Q1,PHOSPHO1,KCTD12,TGOLN2,EGR3,BAHD1,FAM46C,CMTM6,GRHL1,OSBPL3,BCL6,ANKRD12,CNNM4,SNX16,GOT1,DIXDC1,PACSIN1,ZNF365,SCYL3,MAP3K3,SIRT1,PCGF5,HN1L,ASXL1,CBX6,KIF1C,ERBB2IP,ESYT1,ATP1B1,ICMT,ALCAM,ULK2,COL12A1,RTN4RL1,KLF12,P4HA2,DOLPP1,AXL,KLF5,REEP4,SLC31A2,STARD13,PPP2R5D,HOXC13,CTHRC1,SORT1,FARP1,RUNX2,RBM24,CPEB4,ZNF395,FRMD6,UBASH3B,MAN1A2,BACE1,CALB2,ARL4C,SORBS3,NOTCH2,DSE,PGAP1,ANO1,SIX4,LMNA,M6PR,FRY,RNF128,FLRT3,RIMS3,PAK2,FNIP1,ITM2C,GAD1,RIMS2,SOCS5,SNX7,PDGFC,PHF20L1,VAMP3,FURIN,PPARA,WHSC1,SCRIB,LRRC1,FAM73B,SPTLC2,C3orf58,MUM1L1,MAP1B,USP6,MAPKAPK2,GALNT3,ARHGAP24,ONECUT1,SLC6A6,LDLRAP1,CCDC6,SLC35B3,AMMECR1,RAP2C,CSGALNACT1,SH3BGRL2,SHROOM2,CPEB2,AFAP1,ACOT7,ESYT2,DOCK9 |
| 2.893e-09 | -19.66 | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | MSigDB lists | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | 215 | 65 | 17758 | 2588 |
IL15,DNAJC3,TAP1,SOD2,SLC7A2,SNX9,SPSB1,MXD1,NOV,ARHGAP42,ANKRD12,IFIT1,NFKB2,DOCK4,RIPK2,TNIP1,CITED4,USP18,C3orf52,C15orf39,RNF19B,SOCS3,RAB11FIP1,ZNF165,NFKBIZ,MAFF,DDX58,NFKBIE,SDC4,SERPINB9,ELOVL7,DSE,ETS1,NFAT5,ICAM1,TMCC3,HDAC9,BMP2,CXCL16,ITGB8,LYPD3,DRAM1,SGK1,RFX5,MAST4,AMOTL2,GCLC,PLAUR,NUB1,TMEM133,RAB3IP,IFIT3,CD83,FRMD4B,BTG1,NFKBIA,SLC2A6,CLIP4,EFNA1,CMPK2,IFIH1,SERPINB1,OCLN,IRF1,EHD1 |
| 2.894e-09 | -19.66 | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP | 192 | 60 | 17758 | 2588 |
ARHGAP11A,MTM1,SPC25,DEPDC1,FOXM1,TUBB4B,CKAP2,CENPI,CDCA3,KIF23,RACGAP1,NUF2,STIL,CENPN,CKAP5,TOP2A,APLP2,E2F7,PCNA,CCNA2,PASK,NEK2,CKS1B,KIF22,BUB1,MXD3,HMMR,PLK1,PSRC1,CENPA,KIF20A,ASPM,PBK,MYBL2,EZR,CKAP2L,CDCA2,KIF20B,AURKB,PIF1,ANLN,CCNF,CDC25C,SKA1,CDK1,C4orf27,PRIM1,FAM64A,CDCA7L,CDCA5,FAM114A1,AURKA,CENPE,NCAPG2,GEN1,CCNB2,UBE2C,CBX5,E2F8,MELK |
| 2.901e-09 | -19.66 | oesophagus | COSMIC cancer mutations | oesophagus | 15768 | 2377 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,XRCC6BP1,TANC1,ZNF618,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,RECQL,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,ZNF704,CBX7,MAMDC2,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,E2F7,TMEM87B,RNF128,CD9,CCDC82,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,PARP14,MAN1A2,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,GPR180,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,FURIN,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,ALPK3,RHOBTB2,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,ATP5H,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,MYLIP,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,NQO1,LFNG,APOO,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,GIGYF1,EBF2,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,DAG1,PTGS2,PAFAH1B3,RBL1,ABHD12,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERCC6L,HMGN3,GDF15,LBR,AIP,IL22RA1,VPS26A,PARM1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,CKAP5,FJX1,FUT8,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,MAP1LC3B,ERP29,HTR1D,ADPRHL1,SIPA1L2,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,LAP3,ACBD3,USP18,ARHGDIB,MADD,TDRD7,SH3GLB2,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,FAM81A,QSOX2,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,SAV1,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,GNPTAB,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,CASP3,LTBP1,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,EGFL7,PITPNA,KLF7,FBXW5,SLC25A24,ZSWIM5,IL15,SLC2A8,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,UBE2D2,HOXB13,GEM,LRRC57 |
| 2.935e-09 | -19.65 | cell projection morphogenesis | biological process | GO:0048858 | 947 | 207 | 16441 | 2455 |
MYL9,EMX1,CFAP74,UGT8,AGRN,AK7,EPHA4,CCNO,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,WEE1,RPS6KA2,PSMD1,LRRC6,SHC3,DPYSL2,PSMC2,DLG1,DNM2,TRPC1,NTN4,MYH14,CTTN,PACSIN1,BTBD3,TIAM1,RASGRP1,DNAAF3,ATL1,SPEF2,CELSR2,FOPNL,RNF165,EZR,ULK2,DZIP1L,DPYSL3,PLCG1,MAP2,LIMK1,TRAF3IP1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,PSMD7,RAB23,CALM3,DUSP5,SSX2IP,RAC2,VASP,IGF1R,LRRN2,OCRL,FLRT3,COL6A1,PAK2,CACNA1D,NTN1,WNT3A,NCAM1,TTLL1,PSMA5,DNAI1,DPYSL5,CEP89,B9D2,RGMB,CALM1,KIF20B,EPHA1,NPHP3,ILK,DPYSL4,RANBP9,NFIB,PSMA4,EGFR,RASA1,CDK5R1,RHOB,ONECUT1,SEMA4D,MATN2,WDR19,AURKA,PITPNA,NR4A2,EFNA1,B4GAT1,CFAP20,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,KLF7,EHD1,SPRED1,TCTN2,PSME2,IQGAP1,RPS6KA1,C5orf30,ERBB2,RASGRP3,ZMYND10,STIL,TTC21B,PDGFA,ARTN,DACT1,DAB2IP,EPHB4,RASGEF1A,DLG3,SNX10,ETV4,FRS3,SEMA3B,COL6A2,PRKCQ,SLC11A2,ALCAM,MYL12A,DAG1,ARHGAP35,CEP162,EPHA10,IRS2,FYN,JAK1,SLC9A6,PSMD3,WWTR1,SPTBN5,NRG1,EFNA5,PLXND1,LIFR,COBL,ATMIN,TTC8,COL9A3,FARP1,PACSIN2,ARHGEF11,ARHGEF7,POC1B,LRP4,FLOT1,NES,PSMD10,COL4A5,PLPPR4,FGF19,EFNB1,ITGA2B,NRP2,RND1,NEO1,GBX2,KIF5B,ANK1,PTEN,BMP7,SGK1,ERBB3,RPGR,S100A6,CAMK2G,FARP2,RASGRF1,ARHGEF28,B3GNT2,RHOA,PSMB4,CFAP46,FMN1,RAPGEF2,GRIN1,YES1,RAB3IP,BBS2,SPAG1,ABLIM2,MAP1B,CNTNAP1,FGFR2,FGF18,RYK,NR4A3,PGRMC1,GRIN2D,ITGAV,CEP41,L1CAM,NGEF,RGMA |
| 3.006e-09 | -19.62 | cellular protein metabolic process | biological process | GO:0044267 | 3550 | 642 | 16441 | 2455 |
TRIM24,ADD1,MRPS15,TRIM5,DNAJC3,HEXB,RET,XIAP,FBXO2,NRG2,IL18,MORF4L2,BARD1,SPSB1,GRM5,CALM2,DAPK2,WEE1,PSMD1,TGFBR3,MUC4,UBE2T,FUT1,CRY2,PPP1CA,PIK3CD,TINAGL1,TIPARP,CPE,MGAT5,TUBA4A,NEK4,FBXL16,TNIP1,RNF11,MTRF1L,KDELR3,LOXL2,ICMT,RNF19B,ARF4,PIAS3,LIMK1,MYLK,NOD2,MAP3K11,HDAC1,MRPS28,RNASEL,ITPKA,GAB1,GGA1,NUAK1,SEC61G,SOX9,ZNRF3,MERTK,LMNA,RABGGTA,ATG4A,MARCH8,FBXO7,NEK2,FBXL14,PCYOX1,MAP3K9,USP38,USP1,ALPK1,STT3B,MYDGF,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,TTLL1,PPP6R1,NAGPA,UFD1L,MAPKAPK3,STAT4,ERO1A,SHARPIN,ELK1,ILK,TP53INP2,PSMA4,STK17A,PTPRF,NCOA3,FNTA,MTFMT,TIMM8A,SETD3,TEX30,AURKA,STK39,B4GAT1,ALG2,CFAP20,NUP58,RPS6KA3,RUSC1,EGLN1,DMPK,MTM1,TUBB4B,GALNT12,INPP5D,PTTG1,WDTC1,TESK2,MAPK4,GRK6,MVB12B,PRKACA,MOCS1,CCND1,MUC16,RNF220,SP100,RASGEF1A,RNF169,SSH3,SEC61B,RIPK2,PTPN9,VPS4B,XRCC6BP1,IRS2,CDK19,WFS1,AXL,WWTR1,TRABD2A,MAPK12,TAOK2,HSP90B1,MAN1A2,BACE1,DCAF7,TRAF2,CCM2,PDIA3,CTSZ,PKN1,TSPAN17,DTX3L,CAPN2,FUT2,IRAK1,CTSC,ARSG,ALG13,MGAT4A,CST3,WWP1,IGFBP2,MAPK11,RAG1,CRTAP,RAPGEF2,PIK3R1,DUSP23,EIF5A2,NUB1,GRIN1,UBE2A,PIM3,NEURL1B,TXK,GALNT3,DCAF10,BTG1,RPL12,PLOD2,ATXN7L3,ACVRL1,DBI,PPM1H,ITGAV,NUP37,WDR45B,PHC1,UNKL,TNK1,TRIM2,PPM1J,CUL4B,EPHA4,SUDS3,LMCD1,DNAJB11,MGAT5B,HDAC6,PDGFB,PIGL,SPTB,NUP210,RPS6KA2,SHC3,P4HB,MKRN3,PSMC2,PASK,DUSP10,TRAM1,PLK1,MARK1,PTPN18,C12orf65,PRKRA,CDK1,VCP,KDM4D,TRIM9,MSL1,WIPI1,P4HA2,DOLPP1,TTC9,POMT1,PRKAA2,LMTK3,DNAJB2,RASA2,UBASH3B,PSMD7,ADCK5,RAB6A,B4GALT4,PGAP1,B4GALNT1,BMP2,UBE2Q2,IGF1R,PAK2,TBCD,SLC30A6,EXOC8,MDFIC,PIM1,CKAP4,PSMA5,MRPS33,USP31,TESK1,MGAT4B,KBTBD8,STRADB,EIF2AK1,PDK3,ZDHHC3,G2E3,NMT2,CDK5R1,MAPKAPK2,PHLPP2,KBTBD2,P4HA3,ZDHHC7,CTBP1,RNF146,USP43,RAD21,P3H2,CTDSPL,P2RX7,ERBB2,RASGRP3,KBTBD11,PER2,CDK14,RAD23A,PDGFA,KMT5C,PPME1,ZDHHC23,PLK4,NOTCH3,LMAN1,EGLN3,CTDSP2,CTH,SIRT1,PPIF,ERLEC1,TCEB2,AKT1,CDC20,PTGER4,DNAJC10,PTPRJ,IDE,ATP1A1,PSMD3,PTK7,STK38,CHMP4B,RPL22,ST3GAL1,POMGNT2,ZC3HC1,CTDSP1,MAN2B2,CMAS,PINK1,DYRK3,CPEB4,TRAPPC10,KLHL13,TAB3,CTSB,GNE,PSMD10,JAG2,DNAJB9,PPP2R3A,ZDHHC21,CDK16,UBE2J1,SGK1,TRIM21,BUB1,SYK,CAMK2G,GCNT1,DUSP1,MLEC,PSMB4,AMFR,PLAUR,COL7A1,PELI3,MAPK8IP1,USP6,PRDX4,FUCA1,SERPINA1,SCG2,FGF18,SPCS3,NDFIP1,UBE2C,HIPK3,ACVR1,HSPG2,SSH1,CUL1,PSME1,NANS,CAMK1D,CCNB1,PJA2,PICK1,ASPHD2,PAK6,IL31RA,PALD1,PIK3CA,MARCH2,TFG,METAP2,SPATA18,ACVR1C,PBK,CDYL,BNIP3L,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,POR,ULK2,SGPP1,AREG,PLK2,GNPTAB,SH2D3C,PPP2R4,PRDM5,EIF4EBP2,MAPK13,TRAF5,MRPL44,CDK17,DHPS,PRKAA1,NOTCH2,HERC6,TNFRSF19,BMP2K,SH3RF2,CALR,ZNRF2,RPL39,PPP4R1,PRKG1,OPN3,ADCK2,DAPK1,TPST1,MAST4,EEF1D,TMED2,TRAK2,SOCS5,GFPT1,PIGC,B3GNT7,DDB2,PMPCB,MMD,CALM1,PTPRH,WHSC1,EPHA1,KDM3A,JADE2,FBXO10,RASA1,MMP15,PRKAG2,PELI2,CSNK1G1,ZDHHC20,PIAS2,AGBL5,CDK18,MAP3K5,IFIH1,NRBP1,ELK4,SPRED1,DLGAP5,RPS6KA1,SUZ12,RNF182,DDR1,FLT3,ART5,EPM2A,DOK4,FICD,DAB2IP,EPHB4,PHKA2,LGMN,ATG4D,SEC23A,PRKCQ,PKMYT1,ASB13,B3GALNT2,CBL,ZMPSTE24,EPHA10,FYN,DDOST,JAK1,STK26,KIAA1804,TRIOBP,PPP1CB,NRG1,MLKL,B4GALT3,AREL1,OTUD5,MRPS9,IGFBP6,CDCA3,HERC5,CBLL1,FBXO6,FGF19,WWP2,RNF128,MGAT1,PTEN,FUT8,SGK3,ERCC2,ERBB3,MAP3K7,TRIM62,NCOA2,RASGRF1,B3GNT2,CASK,FURIN,PARP4,FBXO9,C1GALT1C1,UBAC1,YES1,FOS,ARSK,CRTC2,FGFR2,PRDX3,RYK,GRIN2D,LRRK1,ARSB,CPEB2,MELK,USP16,CCNC,FAF2,CAMKK1,UBE2Z,UBE2Q1,VARS2,TAF6L,DNER,TRIM68,ADPRHL1,CDKL5,DLG1,ASH2L,PTPRE,RASGRP1,STK35,TRIM8,ASXL1,ITCH,USP18,RNF165,MRPS18A,ROR1,MRPS36,STK17B,ADRBK2,MAN2A2,FASTKD1,UEVLD,IARS2,CAB39,PPP2R5D,PSMC1,CPPED1,PCSK5,PPP1R12A,ASB9,ASL,CALM3,TEC,PHLPP1,ADAMTSL4,DUSP5,B3GALNT1,OTUD1,FAM20C,PRKCI,SRP54,NPTN,ZRANB1,GAD1,MDFI,GYLTL1B,FBXO8,PDIK1L,EGFR,INSR,UAP1,PLPP3,DCUN1D1,ALPK3,CTSA,YOD1,JAK3,FBXW5,LMO7,PAX6,IL15,PSME2,HDAC11,PDIA5,EXT2,SAP130,SETDB2,KIF14,ZDHHC12,RPN2,PDIA6,LOXL1,F2R,SCYL3,FRS3,SEPHS1,MAP3K3,TAF5,PTPRU,MRPS35,DUSP4,CDC25C,MAP3K6,SOCS3,JADE1,HSF4,PEX2,SPTBN5,ABCA1,CBX4,JKAMP,CIT,SHPRH,TGFBR1,NOTUM,TRIB2,SBF1,POMGNT1,HDAC9,KIF5B,ADRBK1,A4GALT,RRBP1,TRIM3,IQGAP3,SLC35A1,MYO5A,B3GALT6,DCAF6,RAB3B,ADAM17,RC3H2,RUNX3,CTSL,KLHL2,TRIM69,CTSV,DTX4,UBE2D2,TADA2B,ARRB1,OTUB2,GLB1,PLOD3,CEP41 |
| 3.059e-09 | -19.61 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | 234 | 69 | 17758 | 2588 |
SIGIRR,IL15RA,EPAS1,HEXB,TAP1,SOD2,BCL2L1,PHLDA1,IRF2,MTMR11,ETHE1,IL1RAP,LAMP3,DOCK4,CD55,RIPK2,LGALS8,SLC39A8,CYB5R2,LYRM1,SAT1,MRPS18A,LHFPL2,RNF19B,CASP4,SOCS3,CARHSP1,FYN,MID1IP1,WIPI1,CANT1,IRF7,ITPKA,ABCA1,GRN,GSDMD,ANXA3,KLF2,SERPINE2,CTSB,HERC5,RABGGTA,TIMP1,FUT8,ZMYM1,PIKFYVE,DUSP1,P2RX4,TGIF1,MOSPD2,PLSCR1,PLAUR,OXR1,FHL2,PYGL,DCTN6,IL1R1,SLCO4A1,ETS2,UAP1,SERPINA1,RND3,NMI,APPL2,OSMR,FGD6,MAP3K5,SERPINB1,EGLN1 |
| 3.184e-09 | -19.57 | HALLMARK_GLYCOLYSIS | MSigDB lists | HALLMARK_GLYCOLYSIS | 197 | 61 | 17758 | 2588 |
GALK1,TXN,ENO2,UGP2,AGRN,DEPDC1,GNPDA1,SLC25A13,GNE,SOX9,BIK,PKP2,IL13RA1,B4GALT4,SDC1,MERTK,EXT2,CHST2,CHPF,ELF3,IER3,ARTN,XYLT2,GPC3,FUT8,TPST1,GYS1,GOT1,ALDH7A1,AK3,PHKA2,EGLN3,CITED2,CTH,HMMR,B3GALT6,GFPT1,QSOX1,SOD1,CENPA,KIF20A,COG2,GUSB,GCLC,AK4,KDELR3,PYGL,PDK3,IDH1,DPYSL4,CDK1,CYB5A,EGFR,GLCE,IRS2,PLOD2,P4HA2,AURKA,MDH1,NDST3,RRAGD |
| 3.370e-09 | -19.51 | GNF2_CKS2 | MSigDB lists | GNF2_CKS2 | 50 | 25 | 17758 | 2588 |
HMMR,ZWINT,DLGAP5,KIF20A,FOXM1,CKAP2,ASPM,PTTG1,CDC20,NDC80,CDCA3,RACGAP1,NUSAP1,CDK1,FANCI,TOP2A,PCNA,CCNA2,PLK4,PRC1,CENPE,CCNB2,SMC4,CKS2,METAP2 |
| 3.432e-09 | -19.49 | positive regulation of macromolecule metabolic process | biological process | GO:0010604 | 2797 | 520 | 16441 | 2455 |
TRIM24,TRIM5,DNAJC3,HEXB,RET,XIAP,NRG2,IL18,MORF4L2,SNX9,BARD1,CARD10,PHF1,GRM5,TP73,NPM2,CALM2,PSMD1,DNM2,PIK3CD,TIPARP,NEK4,VPS11,SMARCA2,TNIP1,SPRTN,TFAP2C,PRKAR2B,F12,RNF19B,ARF4,PIAS3,PLCG1,ANKRD6,NOD2,MAP3K11,HDAC1,RNASEL,HSPB1,E2F8,GAB1,HOXC13,GGA1,ITGA6,SOX9,LMNA,ELF3,TFAP4,NEK2,MAP3K9,MYDGF,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,SALL4,MAPKAPK3,STAT4,PYM1,FHL2,MYBL2,ELK1,ILK,TP53INP2,PSMA4,NCOA3,FNTA,ETS2,SEMA4D,SETD3,AURKA,STK39,GDF11,RPS6KA3,TMEM173,XDH,GRHL2,PRKACA,APC2,CCND1,ST5,CDH1,SP100,DACT1,RASGEF1A,MYT1,ETV4,PSRC1,RIPK2,FZD4,CDCA2,PXYLP1,GTF2A2,EBF2,NFIX,IRS2,WFS1,WWTR1,ARNT,MAPK12,TAOK2,NKX3-1,TNRC6C,CKAP2,TRAF2,SDC4,FLOT1,PKN1,ETS1,NFAT5,ICAM1,PDCD10,ITGB8,IRAK1,CTSC,KNDC1,GPC3,MCF2L,CST3,BAX,MAPK11,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,ABLIM2,TXK,PITX2,ATXN7L3,NR1D2,ACVRL1,NR4A3,CENPE,HMGA1,OSR1,CD81,USF2,SHOX2,FOXA1,AGRN,EPAS1,CNOT8,CUL4B,EPHA4,ARFGEF1,NENF,HDAC6,PDGFB,SPTB,FANCI,TFAP2E,PCNA,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,ELF5,PASK,MITF,TNFRSF18,MYBL1,ZNF462,PLK1,THRB,PCGF5,CITED4,NFE2L1,EZR,EAF2,CDK1,VCP,KDM4D,KLF12,PRKCDBP,MAFF,RUNX2,DNAJB2,RASA2,PSMD7,SORBS3,FBLN1,BMP2,RB1,DAZAP1,IGF1R,GATA2,PAK2,MDFIC,PIM1,WNT3A,PSMA5,RGMB,STRADB,SCRIB,BCL2L13,CDK5R1,MAPKAPK2,CSF1,NLRC5,CTBP1,RAD21,AVPI1,UPF3B,FOXM1,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,LPIN3,EMP2,STIL,BCAP31,IER3,PDGFA,LMO4,PLCG2,BCL6,CDH3,NOTCH3,EGLN3,DVL2,CTH,SIRT1,TIMP2,TCEB2,AKT1,CDC20,SERTAD3,RBL1,PSMD3,EFNA5,IRF7,CNEP1R1,PINK1,CD63,TAB3,DAP,PSMD10,GDF15,HMGN3,PARM1,PPP2R3A,GBX2,GTF2F2,TFAP2A,TRIM21,SYK,CAMK2G,NFE2L3,HES1,RHOA,PSMB4,HMGN5,NR3C1,PLAUR,PPARA,PRICKLE1,MAML2,BCL10,BANK1,FGF18,NMI,E2F1,PPP2R3C,PKD2,NDFIP1,UBE2C,ACVR1,TXN,LGR4,GATA3,CUL1,PSME1,CAMK1D,SEPT4,CCNB1,PICK1,PAK6,HELZ2,CTGF,ZFP36,FOSB,IL31RA,PIK3CA,IRF2,ACVR1C,CASP9,AURKB,SAV1,LDB2,AHRR,AREG,TBX1,PLK2,NKD1,PPP2R4,F2RL1,TRAF5,DDX58,KLF2,CDKN1C,PRKAA1,PSIP1,MECOM,CALR,ITGA3,CYR61,DAPK1,SORL1,RIMS2,SOCS5,MFI2,MMD,CALM1,WHSC1,CYFIP2,KDM3A,NFIB,RASA1,FAS,PRKAG2,SERTAD2,PELI2,ARAP1,PIAS2,NR4A2,EFNA1,MAP3K5,IRF1,SPRED1,DLGAP5,ARMCX3,IQGAP1,RPS6KA1,THRA,FLT3,CD46,CCNA2,RALB,CDKN1B,DAB2IP,OSBPL7,MED30,FOXJ2,SLC11A2,PRKCQ,PYGO1,FZD7,FYN,PPP2R5A,JAK1,STK26,NGFRAP1,STAT1,KIAA1804,SLC27A1,NRG1,KLF5,ATMIN,PRKAR1A,PCOLCE,PBX3,FGF19,SIX4,TEAD3,WWP2,E2F7,RNF128,PTEN,ERBB3,ERCC2,MAP3K7,CITED2,TRIM62,SPRY2,MSH6,NCOA2,PDGFC,RASGRF1,CASK,TEF,VAMP3,FURIN,YES1,FOS,GPLD1,CRTC2,PRDX3,FGFR2,RYK,GRIN2D,LRRK1,GPER1,FZD5,ESPL1,USP16,JARID2,RGMA,CCNC,CASP3,CAMKK1,ERP29,EPCAM,HSF2,GRHL1,DLG1,ASH2L,ARNT2,SLC39A10,RASGRP1,SOD1,TRIM8,ASXL1,ITCH,SEC14L2,MDK,GPRC5B,MADD,CAB39,PSMC1,NR2C2,PPP1R12A,BVES,ETV5,ASB9,CALM3,TEC,DUSP5,EBF4,SUCO,PRKCI,FNIP1,BRAT1,NPTN,CCDC88A,MDFI,ELK3,PDE5A,EGFR,BCAR3,ONECUT1,NUDT16,INSR,PLPP3,NFKBIA,DCUN1D1,JAK3,RARG,TOB1,PROM2,KLF7,PAX6,SORBS1,IL15,PSME2,OSR2,SS18,KIF14,SMO,TWIST1,ZBTB49,EPB41L4B,ECE1,NFKB2,F2R,HSPA2,CHP1,FRS3,UPF3A,SOAT1,MAP3K3,BAG4,ERBB2IP,CD40,MAP3K6,HSF4,JADE1,STAT6,TLE1,SPTBN5,AKNA,GLIS3,ANXA3,ARHGEF11,SH3D19,SERPINB9,TGFBR1,TRIB2,TOP2A,IRF2BPL,CARD8,ADORA1,BMP7,TOX2,BRD7,H2AFY,ACTA2,IQGAP3,ADAM17,DCAF6,WNT10B,NR4A1,GCLC,RGCC,RUNX3,MPV17L2,CASP7,RAP2C,TADA2B,ARRB1,ZMIZ1,SOX8,AHR |
| 3.446e-09 | -19.49 | regulation of GTPase activity | biological process | GO:0043087 | 553 | 134 | 16441 | 2455 |
AGRN,EPHA4,ARFGEF1,F11R,SNX9,DENND2D,RIC1,ELMOD2,ARHGEF10L,SIPA1L2,ARHGAP42,RGS12,RABEP2,ARHGEF37,CDKL5,RGS3,RGS5,RP2,TIAM1,RASGRP1,SOD1,ARHGDIB,ABR,ARHGEF26,PLEKHG6,TBC1D17,ARHGEF19,SH2D3C,MADD,AGFG2,RAP1GAP,STARD13,FGD1,ARAP3,TBC1D1,BVES,ITGA6,RASA2,RACGAP1,DOCK11,RALGPS2,SNX18,RINL,OCRL,RANBP1,FAM13B,TBCD,PRKG1,FNIP1,ALS2CL,TMED2,TBC1D8B,SPATA13,FBXO8,SCRIB,EPHA1,RASA1,RASGRP2,GNAS,BCAR3,TSC1,SEMA4D,SH3BP4,ARAP1,FGD6,PROM2,DOCK9,PLEKHG3,ARHGAP11A,IQGAP1,RALBP1,RGS20,ERBB2,RASGRP3,EPS8L2,ARHGEF16,ACAP2,ST5,SH3BP1,FICD,BCL6,TAX1BP3,DAB2IP,RASGEF1A,TBC1D10B,DOCK4,CD40,DOCK5,ARHGAP35,CORO1C,SIPA1L1,PLEKHG1,EFNA5,RGS14,ARHGAP4,ARFGEF3,DENND5B,FARP1,ARHGEF3,DEPDC1,ARHGEF11,ARHGEF7,SBF1,ARHGEF40,ICAM1,SYDE2,SNX13,LLGL2,MCF2L,KNDC1,IQGAP3,SPRY2,RPGR,FARP2,RASGRF1,ARHGEF28,ARAP2,RAPGEF2,DENND1B,STMN3,RAB3IP,GRTP1,ARHGAP24,RGS9,RCBTB2,RIN3,ARRB1,ARFGAP3,TBC1D4,ARHGEF9,CPEB2,RAB3IL1,ARHGEF4,NGEF |
| 3.505e-09 | -19.47 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | 347 | 92 | 17758 | 2588 |
SUN1,LMO7,ILDR1,NLRX1,ST14,FHDC1,PLA2G16,SYTL2,ARHGEF16,CDS1,RGS12,SCNN1A,TGFBR3,RPS6KA2,GRHL1,MITF,DLG1,AOX1,SERINC2,CLDN4,TAX1BP3,TINAGL1,TSPAN1,SMAGP,FBXL16,TMEM43,SLC39A8,SNTB2,CASP9,CLSTN1,EZR,KIF1C,BCL7B,MCFD2,ICMT,IRX3,MID1IP1,RBM47,SIPA1L1,TRIOBP,LNP1,COBL,CAPN1,ANXA11,FAM134B,PRKAA2,PRSS8,LMTK3,LRRFIP2,MACC1,SH3D19,NFAT5,ELF3,IL17RB,FOXP2,DIRAS3,ITGB8,CTSC,KCNK5,RUNDC3B,OPN3,FAIM,SGCB,C12orf75,ALDH3A2,PSMA5,RBMS2,EPB41L5,SHMT1,PARP4,PLEKHA7,PRICKLE1,PLS1,EPHA1,RAB3IP,FNDC3A,AIF1L,SPTLC2,BCAR1,BBS2,NFIB,FRMD4B,GALNT3,MMP15,PROM1,TJP3,FAAH,PITPNA,OSCP1,FHL1,AHR,OCLN |
| 3.610e-09 | -19.44 | GSE7852_TREG_VS_TCONV_LN_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_LN_UP | 193 | 60 | 17758 | 2588 |
UNKL,ATP9A,NDRG1,FRMD6,UBASH3B,CD274,PHLPP1,NFAT5,MXD1,HDAC9,RABEP2,SNX18,CASC4,OSBPL3,ZDHHC23,TNFRSF18,MDFIC,NTN4,TMEM64,LMAN1,RASGEF1A,F2R,ITM2C,TMBIM1,SOAT1,SH3BGRL,CORO2A,MPP1,KIF13A,DUSP4,PRKRA,RNPEP,SESN1,CASP4,CD83,ENDOD1,ARHGAP24,SWAP70,FNTA,MPRIP,BANK1,ACADSB,ANKRD6,TWSG1,AXL,MATN2,LRIG1,FGD6,SERPINB6,NFKBIZ,ITGAV,TANC2,CD81,TBC1D4,NR3C2,AHR,MELK,ACOT7,CPPED1,RRAGD |
| 3.699e-09 | -19.42 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | 429 | 108 | 17758 | 2588 |
UNC93B1,TXN,IL15RA,TRIM5,CAST,SOD2,KCTD12,IL18,PDGFRL,CCNL1,MXD1,APOBEC3B,ACAP2,SETDB2,FAM46A,SP100,ELMO2,METTL7A,ZFP36,KLF3,BCL6,APIP,IFIT1,OAS3,LGMN,PDIA6,TIPARP,DDX59,APOBEC3G,SIRT1,MX1,MBP,LGALS8,AGPS,SLC39A8,USP18,SAT1,PTGER4,RNF19B,SOCS3,RBM47,WDR11,SECTM1,MADD,KLF5,REEP4,LTA4H,CHPT1,DDX58,KLF2,SORT1,PINK1,FRMD4A,SCD5,BLVRB,ARL4C,HERC5,SAMD9,NOTCH2,HERC6,NTAN1,DOCK11,SEPP1,PDXDC1,LGALS3BP,PDIA4,IRF2BPL,CALR,GNS,RB1,ADD3,PIK3AP1,SNX18,ZNRF2,CTSC,SLC16A6,FAM63A,SGK1,CCDC82,H2AFY,WWP1,CTSD,CITED2,ATP2B1,DUSP1,ACBD5,ARAP2,B3GNT2,NR3C1,IFITM3,MPP1,SPATA13,PRICKLE1,BLVRA,IFIT3,SPTLC2,FAS,FUCA1,SCARB2,PRCP,NMI,C1orf21,PLA2G15,CLIP4,DYSF,CMPK2,IFIH1,USF2 |
| 3.704e-09 | -19.41 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | 175 | 56 | 17758 | 2588 |
TNK1,SERPINE2,TUBB4B,CIT,NDC80,KIF23,CALM3,CCNB1,SLC20A1,BARD1,PHLDA1,STIL,SH3KBP1,CALM2,TOP2A,PAK6,PCNA,CCNA2,UBE2T,PLCG2,FJX1,PRC1,PLK4,MSH2,CKS1B,TUBG1,H2AFY,TNFRSF12A,BUB1,KNTC1,MYBL1,HMMR,PLK1,ZWINT,CENPA,ASPM,PLAUR,EIF5A2,CALM1,FHL2,PKMYT1,ANLN,POLD3,KIF11,CDK1,STEAP1,STK17A,PRIM1,RBL1,DCK,ZNF367,CDCA5,E2F1,CENPE,ESPL1,HOXC13 |
| 3.756e-09 | -19.40 | endosome | cellular component | GO:0005768 | 780 | 174 | 17570 | 2579 |
LAMP1,EXPH5,UNC93B1,EPHA4,RET,TGOLN2,SYTL4,SNX9,DNER,SLC9A7,ZFYVE16,RAB15,TM9SF2,RABEP2,STEAP2,DNM2,ABCA2,TUBG1,SNX16,RAB20,MARCH2,LAMP2,VPS11,RNF11,EZR,KIF13A,TCN2,OPTN,WIPI1,KCNK1,ATP7B,RAB11FIP1,ARF6,SLC31A2,F2RL1,RRAGD,STARD3NL,SCOC,GGA1,TMEM55B,HLA-E,HLA-F,RAB23,CNTNAP2,FAM21C,MARCH8,WDFY1,SNX18,ZNRF2,OCRL,EXOC8,PRKCI,SORL1,HLA-C,PIKFYVE,WNT3A,C9orf72,GPR161,SNX7,TRAK2,MMD,CALCRL,ANTXR1,STEAP1,RHOB,EGFR,DGKH,AP1AR,INSR,HTT,RAB31,APPL2,DYSF,PLD1,ARPC2,PLIN3,RUSC1,SNX30,NIPA1,EHD1,MTM1,SLC2A4,NF2,GPR107,IL15,NDRG1,ERBB2,MVB12B,MICALL2,SDF4,ZFYVE9,ATP6V0B,ACAP2,CDH1,WDR44,CDKN1B,STEAP3,ECE1,RAB27B,LGMN,SNX10,FLOT2,F2R,TMEM9,TMBIM1,MYO5B,SNX8,CLCN3,KREMEN2,PANK1,VPS4B,AP5M1,SLC11A2,RAB38,SNX12,FYN,ATP1A1,SLC9A6,CHMP4B,IRF7,GOLIM4,PACSIN2,ANKRD13D,SORT1,TRAPPC10,CD63,TAB3,CTSB,ATP9A,BACE1,FLOT1,TGFBR1,PKN1,PARM1,VPS26A,HLA-A,M6PR,SNX13,RNF128,IRAK1,CST3,KIAA0319,SGK3,PLEKHF1,TRIM3,MAP3K7,TTPA,TPCN1,MYO5A,AMOTL2,SUN2,RHOA,RAB3B,IFITM3,RAPGEF2,VAMP3,DIAPH2,FAM109A,NEURL1B,CPTP,USP6,CTSL,HLA-B,NUCB1,LDLRAP1,CTNS,RAB11FIP2,PRDX3,RIN3,RAP2C,GPER1,FZD5,NDFIP1,ABCG1 |
| 4.085e-09 | -19.32 | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | 318 | 86 | 17758 | 2588 |
PNISR,UPF3B,PAPSS2,TSC22D3,TMEM41B,NANS,STIL,APLP2,BTG3,SCNN1A,CDH1,RABEP2,KIF14,LMO4,DUSP10,ACOX2,BTBD3,S100A13,RASGRP1,LAMP3,TAF5,AGPS,S100A4,CDC20,PRKAR2B,GALNT7,DUSP4,IDH1,ALCAM,PLEKHB1,OPTN,RBM47,INPP4B,MAOA,KLF5,DAP,CYP2J2,BLVRB,PRKAA1,HERC5,KIF23,CYB561,CNTNAP2,SEPP1,S100A2,HOXB2,PSIP1,LBR,RND1,TOP2A,MLPH,TMEM62,FJX1,TSPAN13,LIMCH1,CADPS2,ACAD8,CASD1,S100A6,GPR161,CCDC88A,FAH,TRAK2,SOCS5,QSOX1,DCAF6,KIF20A,PLSCR1,PIK3R1,AK4,KIF11,SPTLC2,CYB5A,RHOB,MAGED2,NAAA,NT5C2,PROM1,SWAP70,DHRS2,DBI,SH3BP4,SERPINB5,UBE2C,FOXA1,MELK |
| 4.085e-09 | -19.32 | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | MSigDB lists | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | 318 | 86 | 17758 | 2588 |
CCNC,TRIM2,UGT8,NQO1,FOXM1,TSC22D3,PTTG1,RET,NDC80,CACNA2D2,SOD2,C5orf30,GATA3,STIL,CHST2,APPBP2,BTG3,SCNN1A,KIF14,LMO4,IL6ST,REEP1,STEAP3,RGS5,TSPAN1,SEPHS1,CPD,CENPA,LGALS8,CDC20,GALNT7,RBM47,AREG,SLC9A6,CORO1C,WFS1,ATP7B,INPP4B,CANT1,PPP1CB,KLF5,ANXA9,HSPB1,PRKAR1A,LASP1,CDK17,ALDH6A1,MTL5,GDF15,GSTP1,LBR,RND1,MYO5C,MLPH,SLC16A6,FUT8,TFAP2A,ECI2,BUB1,TSPAN13,WWP1,MCCC2,GPR161,SPATA20,NFE2L3,SYBU,BLVRA,SPTLC2,NFIB,MFSD7,RHOB,PRDX4,MAGED2,NT5C2,AP1AR,ACADSB,DHRS2,NAT1,WDR19,TCEAL4,SERPINB5,ARHGEF9,TOB1,MELK,CSRP2,FOXA1 |
| 4.147e-09 | -19.30 | NAGASHIMA_NRG1_SIGNALING_UP | MSigDB lists | NAGASHIMA_NRG1_SIGNALING_UP | 171 | 55 | 17758 | 2588 |
KLF2,AVPI1,GDF15,CCNL1,EGR3,PHLDA1,DUSP5,PER2,IER3,AKIRIN1,WEE1,ZYX,CTGF,CYR61,LYPD3,GATA2,FLRT3,ZFP36,FOSB,DUSP10,SGK1,CLDN4,TNFRSF12A,CTTN,EGLN3,TIPARP,ZNF365,CAMK2G,CTH,DUSP1,SEMA3B,HES1,NR4A1,PLAUR,C3orf52,CASP9,FHL2,SERTAD3,EZR,DUSP4,ZFAND5,FOS,BCL10,IRS2,SLCO4A1,ETS2,AREG,KBTBD2,NAB2,NR4A3,NR4A2,GEM,F2RL1,MAFF,FOXA1 |
| 4.285e-09 | -19.27 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | 250 | 72 | 17758 | 2588 |
SLC35D2,TXN,NQO1,ST14,RPS6KA1,F11R,NANS,SH3KBP1,C1orf116,EPS8L2,SYTL2,IER3,CCND1,EPCAM,RABEP2,DOK4,TACSTD2,EPHB4,BTBD3,ANKRD9,TUBA4A,CXXC5,TNIP1,C3orf52,MRPS18A,GALNT7,ATP1B1,POR,CANT1,DHTKD1,FAM195A,ARRDC1,HDAC1,VSIG10,KLF5,CHPT1,MYL12B,TC2N,PACSIN2,PLEKHJ1,ESRP1,FXYD3,DNAJB2,EFHD2,GSTP1,COX7A2,TMEM63A,ELF3,MECOM,MLPH,FUT2,RNF128,LLGL2,TMEM62,RRBP1,ATP8B1,ERBB3,S100A6,GFPT1,ACBD5,CRB3,PLS1,GRTP1,GNA11,GALNT3,DDAH1,TJP3,FA2H,DBI,TMC5,SH3BGRL2,SERPINB1 |
| 4.408e-09 | -19.24 | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | 111 | 41 | 17758 | 2588 |
PRSS8,GRHL2,MACC1,ST14,TSC22D3,FXYD3,ESRP1,F11R,CCNL1,PRRG4,C1orf116,CDS1,ELF3,SCNN1A,CDH1,ZFP36,FOSB,AIM1,CDH3,TACSTD2,MYO5B,SSH3,KLK5,KIAA0040,MBNL3,LITAF,SLC11A2,KLK6,EPHA1,PPP1R14C,EPN3,ATP1A1,KCNK1,SPINT2,OVOL1,SERPINB5,ZNF165,MAL2,EPB41L4A,TC2N,PROM2 |
| 4.544e-09 | -19.21 | SENESE_HDAC3_TARGETS_UP | MSigDB lists | SENESE_HDAC3_TARGETS_UP | 467 | 115 | 17758 | 2588 |
SPRED1,IQGAP1,GALNT12,CUL4B,SOD2,LMCD1,FAM198B,BCL2L1,PHLDA1,CALM2,CD46,WEE1,SRPX,IL6ST,KLF3,ATP13A3,BCL6,STEAP3,IFIT1,ACOX2,CTTN,NFKB2,LMAN1,IL1RAP,GM2A,DOCK4,CD55,CYB5R2,SAT1,EZR,ROR1,DNAJB14,SAV1,CMTM7,DPYSL3,ANKRD10,JAK1,UEVLD,MAP2,CANT1,NFKBIZ,F2RL1,NXT2,CDK17,TRAPPC10,CPEB4,CDKN1C,SERPINE2,TAB3,UBASH3B,ITGA6,CTSB,MAN1A2,ARL4C,FLOT1,MIER3,C6orf106,EFHD2,CALM3,TGFBR1,POMGNT1,NFAT5,HDAC9,AKIRIN1,BMP2,RB1,E2F7,SPP1,ITGB8,OPN3,SLAIN2,NCEH1,TMED2,ATP2B1,CCDC88A,RASGRF1,PDGFC,CASK,ELK3,ZC3H11A,TCFL5,CALM1,VAMP3,IFIT3,LEPR,MAPK8IP1,DCP2,RHOB,FAS,BTG1,AP1AR,SCARB2,SLC6A6,PLEKHH2,TIMP3,ETS2,KBTBD2,TMEM30A,NFKBIA,OTUB2,PGM2L1,NR4A2,EFNA1,LTBP2,HMGA1,PLD1,GEM,TBC1D4,CPEB2,TOB1,DCBLD1,PKIA,TMEM173,ESYT2,USP16 |
| 4.731e-09 | -19.17 | LY_AGING_MIDDLE_DN | MSigDB lists | LY_AGING_MIDDLE_DN | 16 | 13 | 17758 | 2588 |
PLK1,PTGS2,CENPA,CCNA2,FOXM1,CDC20,MYBL2,KIF23,KIF2C,CCNF,CCNB1,UBE2C,KIF11 |
| 4.792e-09 | -19.16 | apoptotic process | biological process | GO:0006915 | 1059 | 226 | 16441 | 2455 |
LAMP1,CASP3,ADD1,GRIK2,RET,SUDS3,XIAP,CUL1,UBE2Z,PSME1,SEPT4,SH3KBP1,TP73,DAPK2,PAK6,RPS6KA2,PSMD1,CTNNB1,CTGF,ELMO2,SIVA1,PSMC2,TNFRSF18,TIAM1,XKR8,CYP1B1,KCNIP3,ACVR1C,ITCH,CASP9,BNIP3L,EAF2,STK17B,CDK1,POR,VCP,ABR,SGPP1,TNS4,SLC25A4,DNM1L,TBX1,MADD,KLF11,UNC5B,ARF6,TRAF5,RTN3,PSMC1,FGD1,BMF,PSMD7,NOTCH2,NCKAP1,PHLPP1,TNFRSF19,ADAMTSL4,LMNA,MECOM,TFAP4,RB1,CYR61,PAK2,MSH2,DAPK1,MAP3K9,FNIP1,SELK,CD70,TNFRSF12A,BRAT1,MYDGF,PIM1,NTN1,WNT3A,PSMA5,PRODH,PTPRH,ERO1A,SHARPIN,SCRIB,CYFIP2,BCL2L13,PSMA4,FBXO10,RHOB,G2E3,FAS,STK17A,FNTA,H1F0,HTT,NFKBIA,ITPR1,MAP3K5,SEMA3A,IFI6,RPS6KA3,TMEM173,DMPK,XDH,IRF1,RAD21,INPP5D,RPS6KA1,PSME2,SOD2,TP53,P2RX7,BLCAP,BCL2L1,AIFM2,PHLDA1,BCAP31,TNFSF9,ZNF385B,ARHGEF16,IER3,CDH1,RALB,CDKN1B,DAB2IP,STEAP3,APIP,EGLN3,SCN2A,CDKN2D,F2R,ATG4D,EBAG9,MX1,SIRT1,PPIF,SLC5A11,EVA1A,RFK,AKT1,RIPK2,HTATIP2,PRKCQ,SLC11A2,CD40,CASP4,JADE1,DNAJC10,NGFRAP1,STK26,PSMD3,STAT1,EFNA5,ARHGAP4,AREL1,AIFM3,ZMAT1,GCLM,ARHGEF3,TAOK2,NKX3-1,SORT1,ARHGEF11,CKAP2,DAP,TRAF2,ARHGEF7,SERPINB9,RASSF7,BIK,PSMD10,TGFBR1,JAG2,PKN1,BEX2,SGPL1,TOP2A,PDCD10,CARD8,ADORA1,CTSC,PTEN,MCF2L,CST3,BAX,DRAM1,SGK1,PLEKHF1,TMBIM6,ADAM15,KANK2,BUB1,ERBB3,ERCC2,MAP3K7,RAG1,FAIM,MSH6,P2RX4,RHOA,PLSCR1,PSMB4,GCLC,PLAUR,PIK3R1,LITAF,TRIM35,PIM3,BCL10,CTSL,CASP7,KIAA0141,TRIM69,PRDX3,FGFR2,E2F1,UACA,ARRB1,ITGAV,GPER1,FZD5,ARHGEF9,HIPK3,AHR,ESPL1,OCLN,MELK,ARHGEF4,NGEF |
| 4.806e-09 | -19.15 | GNF2_BUB1 | MSigDB lists | GNF2_BUB1 | 26 | 17 | 17758 | 2588 |
HMMR,PLK1,KIF20A,FOXM1,ASPM,CDC20,NDC80,CDCA8,KIF2C,AURKB,RANBP1,CKS1B,BUB1,CENPE,CCNB2,ESPL1,MELK |
| 4.810e-09 | -19.15 | membrane | cellular component | GO:0016020 | 8775 | 1423 | 17570 | 2579 |
HECA,IBTK,GRIK2,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,TGOLN2,SNX9,CMTM6,SLC35E4,GRM5,LYPD5,NAPG,MUC4,PAQR5,ATP13A3,DNM2,CLDN4,PPP1CA,TMEM37,WBP4,RNF26,TIAM1,IL10RB,CPE,MGAT5,SMIM20,TMEM98,KDELR3,TMEM151A,PRKAR2B,RNF19B,PNKD,ARF4,LCP1,ABR,ENPP1,PLCG1,ATP7B,NOD2,HSPB1,STARD13,ANXA11,SCN5A,GGA1,SEC61G,ITGA6,RAB23,COX6C,FAM21C,TTYH3,MARCH8,RAC2,ATP5H,MEGF8,FLRT3,PCYOX1,CADPS2,FAM84B,CNGA1,PANX2,MOXD1,ULBP2,MYLIP,DGKG,NUP85,PPP6R1,PAQR7,PQLC3,ERO1A,GOLT1A,GNA11,SFXN5,MAGED2,IL1R1,CACHD1,SLC4A4,ETS2,APMAP,RAET1L,DGAT2,CLMN,OSCP1,STK39,TMEM159,NUP58,TMEM173,RUSC1,DOCK9,DMPK,LFNG,INPP5D,CD82,RHBDL3,APOO,GRK6,MGST2,MVB12B,REPS1,APPBP2,RBM23,MUC16,CDH1,XYLT2,ENPP5,TAX1BP3,LRP11,DLG3,SNX10,MX1,TMCC2,SNX8,TMEM200B,SEC61B,ERMP1,COL6A2,AGPS,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,SNX12,COX20,GABARAPL1,ALDH3B1,SHROOM3,WFS1,CORO1C,AXL,PNPLA6,PRIMA1,SLC25A30,TCAF1,HSP90B1,MPZL1,FAM189A2,BACE1,TRAF2,BIK,SDC4,FLOT1,BTN3A1,CTSZ,PLPPR4,ZNF219,SLC25A43,SGPL1,DIRAS3,SLC25A45,PDCD10,FUT2,ITGB8,IGSF9,GPC3,TMEM62,MGAT4A,FAM20B,CST3,TUBGCP6,BAX,IGFBP2,CASD1,PARP9,ACBD5,PVRL4,PLSCR1,PIK3R1,MRS2,PGBD1,CNTNAP1,LDLRAP1,RPL12,PROM1,PLOD2,RAB11FIP2,SYT7,SLC35B3,PLA2G15,ITGAV,CD81,WDR45B,TMEM131,ILDR1,BCAM,TNK1,ARFGEF1,DNAJB11,F11R,TEX2,NENF,ITPR2,MGAT5B,SPTB,SLC9A3R2,FANCI,SUSD2,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,PSMC2,SLC44A1,TMEM143,ABCA2,NTN4,SCARA3,SMAGP,KCNIP3,MARK1,CELSR2,STAU2,NFE2L1,CR2,ARFRP1,NKAIN1,TMEM164,HS6ST1,TRAM2,PI4K2B,KCNMB4,AGPAT2,ARRDC1,KPNA2,TC2N,HS6ST3,RRAGD,PRSS8,LMTK3,USH1C,LGALS3,FAM234B,FXYD3,RASA2,SLC22A31,PSMD7,ADCK5,RAB6A,NCKAP1,ANO1,B4GALNT1,FRAS1,ICAM5,TBCD,SLC30A6,FCHO1,SELK,TMEM74B,PIM1,FAR2,WNT3A,MPHOSPH9,CKAP4,PCDH1,BTNL9,RGMB,MGAT4B,EMC2,SCRIB,BCL2L13,PRX,NMT2,CDK5R1,C18orf8,RASGRP2,FA2H,COL13A1,PHLPP2,SLC2A6,ZDHHC7,PLD1,CCNB2,CDAN1,SMCO4,RAD21,TMX4,P2RX7,PRR7,PCBP1,EMP2,BCAP31,SYTL2,IER3,PDGFA,WDR44,ZDHHC23,CDH3,VAT1,NOTCH3,OAS3,TMEM64,LMAN1,SULF2,PPIF,CLCN3,AKT1,PTGER4,C3orf33,DAG1,ATP13A2,PTGS2,TAPBP,PTPRJ,IDE,PAFAH1B3,ABHD12,MMP17,MAOA,CHMP4B,EFNA5,IRF7,SYT13,ST3GAL1,TMEM263,FAM134B,ARFGEF3,BIN1,CMAS,PINK1,TOR4A,CDH22,TAB3,CTSB,SCD5,GNAL,MCTP2,ERCC6L,LBR,AIP,IL22RA1,PARM1,VPS26A,DNAJB9,FZD6,NRP2,M6PR,ZDHHC21,CD109,CDK16,ALPP,UBE2J1,SGK1,IL17RA,HMGCL,CPLX1,TSPAN13,SYK,FAM134C,ATP2B1,GCNT1,LRRC24,P2RX4,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,COL7A1,RNPEP,BBS2,TXNDC11,DGKE,USP6,BCL10,CNOT2,ICOSLG,PTGES,ZBTB33,ARHGEF4,GOLGB1,LAMP1,FAM171B,SLC35D2,SSH1,LGR4,HSPG2,VANGL1,TMEM86B,PJA2,PICK1,SLC9A7,ASPHD2,HELZ2,CYP1A1,STIM1,OSBPL3,KCNS3,SERINC2,PIK3CA,SNX16,TACSTD2,HYLS1,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,BNIP3L,SLC35C1,KIF13A,POR,RAB2B,PRIM1,GDE1,SH2D3C,PPP2R4,LRIG1,SPRY4,F2RL1,SLC31A2,SEMA6B,RECQL,MRC2,SCOC,TMEM55B,PRKAA1,APBA1,TNFRSF19,TSPAN7,MESDC2,CALR,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,MSH2,DAPK1,TPST1,ADCK2,TMEM51,PRKG1,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,PRODH,KCNJ12,GCC2,CEP89,ADCK3,LPGAT1,CALM1,DCHS1,PYGL,EPHA1,ATP8B3,ANTXR1,MMP15,SLCO4A1,PLEKHH2,TJP3,FAAH,ZDHHC20,MPP2,ARAP1,APPL2,SAMD8,PLIN3,HOOK1,EHD1,MFSD3,SPRED1,TCTN2,GPR107,ST14,RALBP1,CERCAM,NDRG1,ATP2C2,BLCAP,BCL2L1,TMEM170B,TMEM19,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPS8L2,EPM2A,CD46,ACAP2,RALB,BRI3,PDE4D,EPHB4,OSBPL7,TSPAN1,FLOT2,DOCK4,COG2,CYB5R2,PANK1,UTRN,CLSTN1,TMEM144,ATP1B1,PKMYT1,CBL,B3GALNT2,ITPR3,ALCAM,TRIQK,ATP10D,FZD7,ZMPSTE24,DDOST,POPDC3,FAM210B,TSPAN18,SLC27A3,COBL,MAMDC2,PRKAR1A,PLSCR4,SLC41A1,EPS8,EFHD2,PLD2,EFNB1,ADGRB2,HLA-A,COX7A2,WWP2,SLC25A36,CKAP5,TMEM87B,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,SLC16A5,MSH6,FARP2,PDGFC,ARHGEF28,B3GNT2,TMEM221,UBAC1,YES1,AIF1L,FOS,KIF11,CPTP,DGCR2,SEC14L4,FGFR2,ABCB1,RYK,ERAP1,FZD5,DEF6,MELK,RGMA,UGT8,FAF2,MPP5,MAP1LC3B,SLC8B1,ERP29,ECI1,HTR1D,ZFYVE16,EPCAM,RAB15,CDKL5,CASC4,METTL7A,TRPC1,CTTN,MYRIP,IL1RAP,LAMP3,CERS2,CYP1B1,ITCH,ACBD3,ARHGDIB,TYSND1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CHPT1,NRGN,CAPN1,PCSK5,CD99,ARAP3,SERPINE2,BVES,ABCG2,CALM3,TEC,QSOX2,B3GALNT1,NOXA1,PFKL,OCRL,COL6A1,SUCO,PRKCI,BRAT1,NPTN,HLA-C,C10orf54,GAD1,SLC12A2,CCDC88A,SNX7,PODXL2,SPA17,KIAA1109,NUBP1,C3orf58,MFSD7,STEAP1,INSR,UAP1,TMEM30A,SH3BP4,RAB31,CTSA,SHROOM2,TMEM14A,JAK3,APOL2,RARG,SNX30,DRD1,DYNLRB1,SORBS1,HDAC11,PDIA5,IL27RA,MRAS,SAYSD1,PHLDA1,EXT2,CYP4F11,COX14,KIF14,REEP1,ECE1,EPB41L4B,UPF3A,EBAG9,CHP1,SEPHS1,SOAT1,PTPRU,C3orf52,MRPS35,TMTC2,CD40,CASP4,JADE1,SECTM1,SPTBN5,ABCA1,ENO2,TSPAN15,ARHGEF11,CIT,SH3D19,ARHGEF7,SERPINB9,TGFBR1,SBF1,XPR1,ITGA2B,TMEM63A,KIF5B,ADRBK1,LLGL2,A4GALT,RRBP1,ZDHHC13,ARVCF,SLC35A1,MYO5A,B3GALT6,TMEM245,SYBU,RC3H2,FAM73B,LEPR,ENDOD1,LEMD2,CD8A,SWAP70,RND3,TRIM69,CTSV,SPINT2,FIBCD1,RAP2C,CSGALNACT1,ARRB1,SLC18B1,GRAMD1C,MCUR1,CEP41,PLOD3,CD33,ABCG1,NGEF,DOC2A,ACACB,IL15RA,ADD1,MRPS15,DNAJC3,FBXO2,CACNA2D2,NRG2,LYNX1,MORF4L2,SYTL4,SMIM13,CALM2,ZYX,TGFBR3,RGS12,AP1M2,PQLC2,PSMD1,CYP2S1,CABP1,PPP1R16A,SLC46A1,RDH14,FUT1,PIK3CD,ERAP2,VPS11,LOXL2,F12,ICMT,PPP1R14C,CYP4F3,SLC44A3,PGF,WDR11,GRID2IP,DNM1L,LIMK1,MAP3K11,AGFG2,MRPS28,RELL1,ARF6,FAM169A,TMTC3,CYP2J2,STRN4,SLC36A4,ZNRF3,MERTK,LMNA,FAM189A1,CD22,STT3B,NCAM1,NDUFA12,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,ILK,MEST,SPTLC2,RHOB,CYB5A,PTPRF,SCARB2,SEMA4D,HTT,TIMM8A,ITPR1,OSMR,DYSF,ALG2,B4GAT1,MAL2,DRP2,NDE1,ARPC2,TRPC3,SERPINB1,MTM1,CCDC109B,GRHL2,GALNT12,ETNK1,RGS20,PKP2,IL13RA1,NUF2,PRKACA,APC2,KTN1,TNFSF9,CDS1,CCND1,SCNN1A,LINC00998,RTKN2,ACSL4,RAB27B,ARL4D,TMEM9,SCN3A,ENPP4,LGALS8,NRBF2,FZD4,PLEKHO1,CYS1,SYNE2,PXYLP1,RAB38,IRS2,PEX5,STX10,SLC9A6,SIPA1L1,TRABD2A,RGS14,TTC8,GALK1,TAOK2,FARP1,PARP14,MAN1A2,ANO9,PKN1,NUCB2,KCNC4,TSPAN17,SRPX2,ICAM1,NEO1,CAPN2,CXCL16,ANK1,ADD3,SLC27A6,IRAK1,CTSC,ANKS1B,KCNK5,ALG13,MCF2L,CALD1,PLEKHF1,TMBIM6,ADAM15,ECI2,WWP1,NPTXR,SGCB,ITM2C,TPCN1,S100A6,TMX1,HCN3,MOB4,AMOTL2,FMN1,CTNNAL1,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,GRIN1,EMP3,SNTB1,TXK,GALNT3,ACVRL1,ARFGAP3,FHL1,CENPE,NUP37,CYBRD1,DCBLD1,SIGIRR,UNC93B1,AGRN,EPHA4,NDC80,MCCC1,TP53I11,CDIPT,HDAC6,PDGFB,PIGL,SDC1,SHC3,CNTRL,LMAN2L,TNFRSF18,RGS5,PXMP4,ANO4,TLN2,TRAM1,CD55,MCTP1,HN1L,EZR,ERP44,KLK6,ESYT1,PRKRA,LHFPL2,CLCN2,CDK1,VCP,PLEKHB1,RHEB,OPTN,MFAP3L,PLCH1,WIPI1,DOLPP1,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,TTC9,PIEZO1,POMT1,EPB41L4A,BMF,HLA-F,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,PGAP1,IL18R1,CORO1B,BMP2,VASP,IGF1R,CMTR2,PAK2,EXOC8,TMEM8A,ALDH3A2,ABCC1,CYP26B1,CHSY3,MRPS33,SPATA13,ZDHHC3,EPN3,MOSPD3,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,ATP1B3,TMEM120A,IFI6,NIPA1,KCNAB3,NF2,XYLT1,DGKA,ERBB2,RASGRP3,SLC7A2,FAM198B,LPIN3,CYP26A1,SDF4,CDK14,ATP6V0B,SRPX,EFR3A,N4BP3,PLCG2,SRR,GYS1,SCN2A,FAR1,GM2A,DVL2,SIRT1,CPD,TMTC1,EVA1A,MBP,COQ10B,DNAJC10,DUOX1,RTN4RL1,PRRT4,ATP1A1,PTK7,PSMD3,C1orf43,AIFM3,POMGNT2,NDST3,CNEP1R1,CMTM4,ZC3HC1,COPG1,MAN2B2,GOLIM4,PACSIN2,TM2D2,MFSD14B,TRAPPC10,CD63,ADGRG1,TMEM243,BLVRB,SELL,GABRG2,JAG2,DSE,SIRPA,SLC9A2,MAGEE1,SLC35B4,BUB1,ABCD1,KLF9,SLC45A3,CAMK2G,IGDCC4,DLGAP1,HMMR,MLEC,IFITM3,CRB3,AMFR,LITAF,CAPNS1,CARD19,FXR2,FNDC3A,NPDC1,BCAR1,MAPK8IP1,CD83,TMEM50B,SERPINA1,FAT4,ZMYND19,TMC5,NETO2,PGRMC1,TMEM248,PKD2,SPCS3,FER1L4,NDFIP1,TBC1D4,DIS3L,SUN1,GAA,ACVR1,TMEM41B,ATP8A1,FAM129B,KLC2,TAP1,PLXNA1,CCNB1,PLA2G16,SLC20A1,RIC1,ELMOD2,NCS1,CHST2,CTGF,ELMO2,RGS3,IL31RA,STEAP2,ATRNL1,PACSIN1,TFG,XKR8,LAMP2,ORAI2,TMEM68,SNTB2,MGAM,AGO4,GALNT7,SLC17A5,MCFD2,SLC25A5,SPNS3,ULK2,SGPP1,SFXN1,KDSR,SLC25A4,AREG,GNPTAB,NKD1,SARAF,TMEM8B,UNC5B,TRAF5,RTN3,LZTS1,DDX58,MRPL44,INPPL1,HLA-E,DGKQ,SLC25A27,NDUFA4,SLC1A3,NOTCH2,KIAA1161,PRRG4,ITGA3,SNX18,PIK3AP1,SLC16A6,NECAB3,BDH1,CTPS1,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,CTSD,RIMS2,TMED2,TSPAN33,IGSF3,FAM69A,EPB41L5,FADS2,QSOX1,B3GNT7,PMPCB,MMD,MFI2,B9D2,MICB,AMER1,PTPRH,ANO6,TMEM133,PIP4K2C,VEZT,CYFIP2,PKM,KDM3A,GLT8D2,RASA1,STX3,FAS,DGKH,GABRD,TMEM54,SLC4A3,PCDH19,EFNA1,MAP3K5,NRBP1,PKD1L2,PLA2G4A,SLC2A4,ARMCX3,CEP70,TMEM217,TRIP10,NLRX1,IQGAP1,CAST,BROX,KCTD12,RNF182,CD274,SNN,AIFM2,TMPRSS4,GNB2,SLC25A35,APLP2,FICD,CNNM4,TNPO2,DAB2IP,PHKA2,TMBIM1,TBC1D10B,GPX4,MYO5B,SLC5A11,SEC23A,TMEM43,DMTN,COX11,SLC11A2,PRKCQ,CMTM7,EPHA10,FYN,PPP2R5A,JAK1,STK26,SLC27A1,KLF5,NRG1,RAB29,MLKL,HS3ST3B1,B4GALT3,NR3C2,DENND5B,MRPS9,ANKRD13D,SLC16A14,ATP9A,ARL4C,GPR180,CYB561,SLC35G2,LGALS3BP,RND1,TMCC3,AKIRIN1,SNTA1,PTEN,MGAT1,PRC1,ATP8B1,SLC44A2,MAP3K7,SPRY2,RASGRF1,CASK,ERMAP,MPP1,PARP4,FURIN,VAMP3,C1GALT1C1,LRRC1,GPLD1,NUCB1,RGS9,MAMDC4,CTNS,SLC25A40,GRIN2D,GPER1,NCAPG2,SLC25A38,OCLN,ESYT2,CASP3,TMEM184B,ABHD17B,CPT2,EPHX4,KIF2C,CACNB4,DNER,KREMEN1,TMC1,SH3KBP1,PTCHD4,ABCD4,CHPF,NKAIN3,IMPAD1,TSPAN6,DPYSL2,DLG1,SUN3,RAB20,RP2,MYH14,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TDP1,SOD1,SYNE3,MRPS18A,ROR1,PTGFRN,MRPS36,STK17B,EDNRA,SEC14L2,DHRS13,ADIPOR1,LEMD1,APBA2,RAP1GAP,PSMC1,CPPED1,STARD3NL,PEX6,ELOVL7,ATP6V1E2,PHLPP1,LYSMD4,CA2,LRRN2,KCNN4,FXYD5,KNTC1,NCEH1,KDELR1,PARD3B,GYLTL1B,BTN3A2,EGFR,GLCE,GNAS,FECH,XKRX,TSC1,SLC6A6,PLPP3,NFKBIA,CDCA5,RHOBTB2,PROM2,SLC25A24,IL15,SLC2A8,PSME2,ABCG4,MICALL2,LRRC45,SLC25A48,ZDHHC12,SMO,STEAP3,RPN2,PDIA6,F2R,HSPA2,FRS3,SUSD3,GCA,BAG4,KREMEN2,SLC39A8,OSTM1,AP5M1,IGSF8,ERBB2IP,BFSP1,PEX2,CANT1,VSIG10,PLXND1,CYP2U1,AKNA,REEP4,LIFR,ANXA3,CDS2,SORT1,FRMD6,JKAMP,LRP4,FAM134A,POMGNT1,IL17RB,SNX13,ADORA1,KIAA0319,IQGAP3,SUN2,SYPL1,ADAM17,RAB3B,NR4A1,LRRC66,MPV17L2,MAP1B,HLA-B,MARC1,PRCP,HNRNPH2,GEM,ATP6V1C1,L1CAM,LRRC57,SNPH |
| 4.962e-09 | -19.12 | KIM_WT1_TARGETS_12HR_UP | MSigDB lists | KIM_WT1_TARGETS_12HR_UP | 154 | 51 | 17758 | 2588 |
MYL9,KIF3C,ENO2,DLGAP5,ZNF395,LGR4,ATP9A,ZCCHC24,LRP4,RASSF7,SOX9,EPS8,BLCAP,GDF15,TAF6L,TRIB2,PJA2,DDR1,SLC20A1,NFAT5,C1orf116,KIF5B,TNS3,ADORA1,DOK4,BHLHE41,RUNDC3B,UBE2J1,IFIT1,KLF9,TLN2,MYBL1,ULBP2,IL10RB,IL1RAP,TUBA4A,GFPT1,CASK,OXR1,PLEKHO1,HSPA12A,ATP1B1,FZD7,ENDOD1,TIMP3,AREG,KCNK1,P4HA2,CSF1,MYLK,ZMIZ1 |
| 5.040e-09 | -19.11 | MOHANKUMAR_TLX1_TARGETS_UP | MSigDB lists | MOHANKUMAR_TLX1_TARGETS_UP | 390 | 100 | 17758 | 2588 |
UGP2,EPAS1,TUBB4B,CPT2,FAM102B,MORF4L2,PLA2G16,OAT,SLC20A1,CMTM6,IER3,WEE1,PCNA,CYP1A1,SCNN1A,AP1M2,NUP210,TM9SF2,PAPSS1,SLC44A1,PHTF1,CNNM4,CDH3,RPN2,CPE,SULF2,SEMA3B,PLK1,GCA,SLC39A8,PLEKHO1,CDC20,HTATIP2,NKAIN1,MRPS35,ICMT,ASB13,PTGFRN,CDK1,ZMPSTE24,RBM47,PLK2,CORO1C,IARS2,PPP1CB,ADIPOR1,KPNA2,PIEZO1,GLA,CAPN1,HSP90B1,TAOK2,FRMD4A,DCAF7,CTSB,C6orf106,RAB6A,CRABP2,CORO1B,CALR,TFAP4,RB1,E2F7,FUT8,MSH2,TFAP2A,SORL1,BUB1,NPTN,CTSD,KCTD3,ALDH3A2,PHKG2,RBMS2,ATP2B1,TMED2,EPB41L5,UFD1L,ZWINT,LITAF,MEST,TXNDC11,FBXO10,RHOB,GNAS,DDAH1,TIMP3,H1F0,PRDX3,PRCP,DHRS2,PGRMC1,ARRB1,PCDH19,GLB1,ATP1B3,ZMIZ1,HOOK1,CCNB2,L1CAM |
| 5.097e-09 | -19.09 | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 190 | 59 | 17758 | 2588 |
FARP1,LGALS3,EPAS1,GNPDA1,CKAP2,UBASH3B,ERCC6L,CDCA8,BARD1,HLA-A,NRP2,MAGOHB,CAPN2,PDGFA,E2F7,PIK3AP1,OSBPL3,TOX2,RANBP1,PRC1,NEK2,CKS1B,KIF22,KNTC1,MANF,SGCB,SNX10,TIAM1,TSPAN33,MYO5A,HMMR,PLSCR1,PBK,S100A4,CDC20,MBNL3,CCDC34,AURKB,PIF1,PDK3,DUSP4,ANLN,FRMD4B,PRDX4,ENDOD1,PI4K2B,CASP7,NEIL3,CDCA5,PGRMC1,PKD2,KPNA2,FHL1,GEM,NUP37,AKIP1,NDE1,E2F8,MELK |
| 5.122e-09 | -19.09 | prostate-carcinoma | COSMIC cancer mutations | prostate-carcinoma | 9403 | 1502 | 17775 | 2585 |
HECA,IBTK,GRIK2,AK7,PNPLA2,RET,MCOLN3,TRAPPC8,LACTB2,SNX9,SPSB1,CARD10,LTBP3,SLC35E4,ZNF275,GRM5,CDKN2C,PHYHIP,MUC4,PAQR5,ATP13A3,CRY2,PPP1CA,TMEM37,WBP4,TIAM1,CPE,TIPARP,NEK4,CDA,KDELR3,TMEM151A,TFAP2C,PRKAR2B,ABR,LCP1,PIAS3,ENPP1,PLCG1,ATP7B,CELF5,TRAF3IP1,NOD2,HDAC1,TMOD2,STARD13,HSPB1,ANXA11,SCN5A,ITGA6,RAB23,CCDC64B,TTYH3,ATG4A,TFAP4,FLII,RAC2,ZCCHC17,FRY,FLRT3,FBXL14,MAP3K9,SLAIN2,CADPS2,USP1,USP38,ALPK1,MAPK7,ZMYM1,MOXD1,DGKG,KANK3,NUP85,MCCC2,HPS3,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,SFXN5,GNA11,C11orf45,MAGED2,IL1R1,CACHD1,FNTA,SLC4A4,ETS2,DGAT2,CLMN,OSCP1,GDF11,CBX5,ADAMTS16,DMPK,DOCK9,WDR63,NQO1,LFNG,RHBDL3,APOO,C5orf30,GRK6,MOCS1,REPS1,APPBP2,RBM23,MUC16,ST5,CDH1,XYLT2,ZNF365,ETV4,MYT1,MX1,SNX8,COL6A2,ERMP1,C6orf1,RIPK2,APOBEC3D,PFKFB2,AGPS,PTPN9,SEPT6,SYP,XRCC6BP1,TANC1,GIGYF1,GABARAPL1,NFIX,SPIN3,CCNB3,SHROOM3,CDK19,WFS1,AXL,FAM149A,DMWD,PRIMA1,MAPK12,HSP90B1,MPZL1,FAM189A2,TRAF2,CCM2,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,ZFX,PDCD10,ITGB8,IGSF9,KNDC1,GPC3,MGAT4A,TMEM62,TUBGCP6,BAX,IGFBP2,PARP9,ADAMTS2,PLSCR1,PIK3R1,MRS2,CXorf57,UBE2A,CNTNAP1,RPL12,PROM1,PLOD2,SLC35B3,PLA2G15,PPM1H,FBXO44,ITGAV,CMPK2,ACOT7,TLL2,TMEM131,CCNI,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,GALM,MGAT5B,ITPR2,SPTB,FANCI,CPNE2,RPS6KA2,NUP210,TM9SF2,CTNNB1,P4HB,NPNT,IL6ST,SLC44A1,MITF,ABCA2,NTN4,PLK1,THRB,PTPN18,MARK1,KCNIP3,CELSR2,STAU2,CR2,CKAP2L,NKAIN1,SESN1,DZIP1L,TRIM9,TNS4,PLEKHG6,TRAM2,AGPAT2,KLF12,HOXA9,ZNF367,ARRDC1,HS6ST3,RMND5A,PARP12,RUNX2,USH1C,HJURP,LGALS3,FXYD3,RASA2,PSMD7,SORBS3,ADCK5,RAB6A,NCKAP1,FBLN1,MYO5C,TNS3,FRAS1,ICAM5,SLC30A6,SELK,PIM1,FAR2,NTN1,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,USP31,STRADB,SCRIB,PDK3,BCL2L13,PRX,NMT2,C18orf8,COL13A1,PHLPP2,OTUD6B,SLC2A6,NLRC5,PLD1,SEMA3A,CDAN1,USP43,RAD21,CTDSPL,TP53,RHPN2,P2RX7,BAHD1,STIL,BCAP31,SYTL2,PDGFA,TTC21B,WDR44,TACC2,BCL6,CDH3,GLB1L2,NOTCH3,LMAN1,CTDSP2,SULF2,ERLEC1,AKT1,PTGER4,ACO1,ATP13A2,PTPRJ,RBL1,ABHD12,STK38,MAOA,XRCC3,CHMP4B,EFNA5,SYT13,FAM134B,BIN1,ZMAT1,CMAS,PINK1,CDH22,CPEB4,CTSB,MCTP2,HAL,ERI2,GTF3A,GDF15,NRP2,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,GTF2F2,SGK1,CPLX1,TSPAN13,ALDH7A1,HMGCL,SYK,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,P2RX4,HES1,RHOA,STMN3,DPP9,MAML2,GGH,COL7A1,BCL10,USP6,CNOT2,DDAH1,SMTNL2,SCG2,NEIL3,FGF18,E2F1,SH3BGRL2,HIPK3,ARHGEF4,GOLGB1,FAM171B,LAMP1,LGR4,SSH1,HSPG2,C1orf198,CUL1,PSME1,CAMK1D,NANS,VASH1,PJA2,SLC9A7,ASPHD2,PAK6,TYMP,CYP1A1,ANKS6,ZNF823,STIM1,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,METAP2,SGCE,SPATA18,ACVR1C,CDYL,BNIP3L,KIF13A,LDB2,POR,RAB2B,PRIM1,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,SPRY4,RECQL,MRC2,SCOC,TBC1D1,TMEM55B,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,PSIP1,SH3RF2,CALR,DOPEY2,RALGPS2,ZNRF2,AIM1,MSH2,DAPK1,TMEM51,PRKG1,ADCK2,OSTF1,CACNA1D,KCTD3,SYTL3,ZNF117,GPR161,TRAK2,SOCS5,SPATA20,GCC2,CEP89,ADCK3,LPGAT1,DCHS1,PYGL,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,MMP15,SLCO4A1,PLEKHH2,PELI2,ZDHHC20,C1orf21,PIAS2,MPP2,FAM83D,APPL2,AGBL5,SFMBT1,CABIN1,SAMD8,KLK7,ZBTB34,PER3,PLIN3,IFIH1,EHD1,MFSD3,SPRED1,KIF3C,TCF25,TCTN2,CAPN12,GPR107,DLGAP5,ST14,CCDC110,THRA,NDRG1,CERCAM,RALBP1,ATP2C2,BCL2L1,FLT3,DDR1,CYP39A1,ZFYVE9,EPS8L2,EPM2A,CD46,CCNA2,ACAP2,TRANK1,RALB,EPHB4,RNASEH2A,PDE4D,OSBPL7,TSPAN1,FLOT2,MED30,ATG4D,COG2,PANK1,CLSTN1,UTRN,PKMYT1,ATP1B1,PYGO1,CBL,ITPR3,ALCAM,ATP10D,FZD7,ZMPSTE24,ACAD10,TSPAN18,ZNF704,SLC27A3,COBL,PRKAR1A,PLSCR4,DEPDC1,IGFBP6,SLC41A1,EPS8,CBLL1,HERC5,PBX3,PLD2,DNAH3,FGF19,WWP2,CKAP5,SLC25A36,E2F7,TMEM87B,FUT8,DRAM1,CD9,CCDC82,ERBB3,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ZC3H11A,PAPD7,ZKSCAN2,DIAPH2,C2orf69,YES1,GRTP1,FOS,CDK5RAP1,CRTC2,DCTN6,DGCR2,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR62,FZD5,WDR91,ESPL1,DEF6,RGMA,UGT8,VARS2,ERP29,HTR1D,ZFYVE16,SIPA1L2,HSF2,CASC4,ARHGEF37,SIVA1,ANKFN1,CTTN,MYRIP,IL1RAP,STK35,SP5,LAMP3,CYP1B1,ASXL1,ITCH,ACBD3,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,MADD,TDRD7,SP6,RBM43,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,ZNF395,BVES,PYROXD2,ETV5,ABCG2,FAM81A,ADAMTSL4,DUSP5,QSOX2,SPP1,TYW3,CES2,PFKL,FAM20C,COL6A1,PRKCI,LIMCH1,C10orf54,NPTN,HLA-C,ZRANB1,SLC12A2,CCDC88A,SNED1,MDFI,ELK3,PODXL2,PDE5A,KIAA1109,HEATR5A,NUBP1,STEAP1,RANBP9,SOX13,INSR,UAP1,TMEM30A,SH3BP4,RAB31,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,AFAP1,RARG,SNX30,DRD1,CCNE2,LMO7,DYNLRB1,NCKAP5,LZTFL1,PAX6,SORBS1,HDAC11,PDIA5,IL27RA,MRAS,OSR2,EXT2,KCTD9,SAP130,KIF14,ZBTB49,DIXDC1,EPB41L4B,ECE1,NFKB2,UPF3A,SOAT1,RFK,PTPRU,C3orf52,GLO1,CD40,TMTC2,CDC25C,FANCE,CASP4,SOCS3,ALDH5A1,STAT6,TLE1,RCAN2,SPTBN5,ABCA1,KDELC2,GLIS3,FBLIM1,ARHGEF11,TSPAN15,ARHGEF7,SHPRH,TGFBR1,COL4A5,INTS8,NTAN1,XPR1,HMGXB4,ITGA2B,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,ARVCF,CLIP2,MYO5A,RBMS2,PGM1,DCAF6,WNT10B,SYBU,RC3H2,TTC7A,NDRG3,LEPR,FOXL1,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,RND3,FIBCD1,RAP2C,CSGALNACT1,DTX4,ARRB1,UACA,ZMIZ1,AHR,ABCG1,CD33,NGEF,ACACB,KLK10,TRIM24,ADD1,AASS,TRIM5,DNAJC3,XIAP,CACNA2D2,SMARCAL1,DHX8,NRG2,LYNX1,SYTL4,CA8,BARD1,KIF26A,PHF1,EPDR1,DAPK2,TP73,WEE1,PSMD1,TGFBR3,RGS12,AP1M2,PQLC2,ARHGAP42,KIAA1107,DNAH6,PPP1R16A,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,ERAP2,TUBA4A,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,RNF11,LOXL2,PPP1R14C,MYOM1,CYP4F3,COL12A1,SLC44A3,TRIM47,WDR11,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,MRPS28,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,TMTC3,STRN4,SLC36A4,ZNRF3,MERTK,RAVER2,ELF3,DNPEP,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,NEK2,STT3B,NCAM1,EPHX1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,DCP2,RHOB,DHX32,PTPRF,NAAA,NCOA3,SCARB2,SEMA4D,HTT,ITPR1,DYSF,AURKA,OSMR,ALG2,ARPC2,DRP2,NDE1,TRPC3,ZNF502,RPS6KA3,CSRP2,XDH,EGLN1,ARHGAP11A,GRHL2,FAM131C,ACTR8,ETNK1,TESK2,PKP2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,UHRF1BP1L,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ARL4D,TMEM9,SCN3A,RNF169,ENPP4,LGALS8,FZD4,PLEKHO1,SYNE2,CYS1,CDCA2,RAB38,IRS2,PEX5,STX10,WWTR1,SIPA1L1,INPP4B,PLEKHG1,ARNT,TTC8,FARP1,TAOK2,NKX3-1,RBM24,PARP14,PLEKHJ1,PDIA3,GMCL1,ANO9,PKN1,NUCB2,ETS1,KCNC4,TIPRL,PDIA4,NEO1,DTX3L,CAPN2,CXCL16,ANK1,ADD3,SLC27A6,IRAK1,ANKS1B,FAM160A2,ARSG,CTSC,KCNK5,CALD1,FDXR,PLEKHF1,ADAM15,TMBIM6,MAPK11,WWP1,NPTXR,SGCB,TPCN1,CRTAP,AMOTL2,LCA5,NUDT8,CTNNAL1,FMN1,FAM160A1,BCL9,RAPGEF2,EIF5A2,ELOVL3,GRIN1,PLEKHA7,MYEOV,SNTB1,ABLIM2,TXK,GALNT3,BTG1,NR1D2,CCDC6,ZFP30,CENPE,FHL1,FOXA1,MYL9,SIGIRR,TRIM2,GNPDA1,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,MCCC1,PDGFB,PIGL,CNTRL,MKRN3,DUSP10,RGS5,ANO4,TLN2,MYBL1,S100A13,NEB,CCDC38,ZNF462,CD55,MCTP1,C12orf65,EZR,ERP44,ESYT1,ANLN,IDH1,CLCN2,ZBTB7B,RHEB,VCP,PLEKHB1,DPYSL3,PLCH1,MFAP3L,TBC1D17,WIPI1,MAP2,P4HA2,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,POMT1,GLCCI1,PRKAA2,HLA-F,UBASH3B,CNTNAP2,DOCK11,DHRS3,IL18R1,PGAP1,CORO1B,BMP2,RB1,KIAA0895,IGF1R,GATA2,EXOC8,MDFIC,TMEM8A,PLCB2,PSMA5,ABCC1,C9orf9,CHSY3,CYP26B1,WDR72,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ANKRD29,ZDHHC3,G2E3,MOSPD3,EPN3,MAPKAPK2,DHDH,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,LTBP2,IFI6,RNF146,NF2,UGP2,UPF3B,FOXM1,XYLT1,ZNF28,ERBB2,RASGRP3,CCNL1,LPIN3,PER2,CDK14,RAD23A,SRPX,PLCG2,GYS1,SCN2A,FAR1,DVL2,GM2A,CTH,TMTC1,MBP,FIGNL1,S100A4,CDC20,MYL12A,DUOX1,DNAJC10,PRRT4,ATP1A1,C19orf66,PTK7,PSMD3,ADAMTS14,RPL22,NDST3,ZC3HC1,CMTM4,MAN2B2,COL9A3,GOLIM4,TRAPPC10,MACC1,RUSC2,DAP,SELL,NKRF,CHAC2,JAG2,DSE,PPP2R3A,SIRPA,SLC9A2,BUB1,KLF9,SLC45A3,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,PPARA,AKAP3,PELI3,FXR2,FNDC3A,NPDC1,BCAR1,BSDC1,MAPK8IP1,FUCA1,BANK1,FAT4,ZNF214,ZMYND19,TMC5,CDCA7L,NETO2,FAM117A,TBC1D4,DIS3L,GAA,ACVR1,PPP4R4,TTC39B,TMEM41B,ATP8A1,KLC2,PPFIBP2,PLXNA1,FAM101B,SLC20A1,CHST2,NCS1,RGS3,AOX1,STEAP2,ATRNL1,MTMR11,TFG,PACSIN1,LOC81691,KIFC2,CASP9,HSPA12A,NBPF3,TNS1,AURKB,GALNT7,SLC17A5,CCNF,SAV1,SPNS3,ULK2,AHRR,SLC25A4,RBM47,AREG,PLK2,GNPTAB,NKD1,DHTKD1,TANC2,UNC5B,TRAF5,DLAT,DDX58,MRPL44,CDK17,INPPL1,FRMD4A,KIF23,C6orf106,NOTCH2,SLC1A3,PRRG4,MECOM,ITGA3,PIK3AP1,RUNDC3B,SORL1,TMED2,EEF1D,RIMS2,FAM69A,IGSF3,DNAI1,EPB41L5,DDB2,FADS2,B3GNT7,ZNF84,MMD,AMER1,PTPRH,ANO6,TMEM133,KCTD20,KDM3A,FBXO10,GLT8D2,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,NAB2,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,IRF1,ELK4,PLA2G4A,PLEKHG3,CEP70,TRIP10,S100A11,NLRX1,BROX,CAST,SUZ12,IQGAP1,IRX4,RNF182,AIFM2,MNS1,TMPRSS4,APLP2,ZNF75D,FICD,CDKN1B,CNNM4,DAB2IP,NR2C1,MYO5B,SLC5A11,SEC23A,CAPN6,TMEM43,LYRM1,TEP1,COX11,PRKCQ,BCL7B,SP4,PRDM11,NIN,OSBPL2,EPHA10,FYN,JAK1,PPP2R5A,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,KLF5,ZC3H12B,NR3C2,ATMIN,DENND5B,OTUD5,WASF3,ARHGEF3,ATP9A,CYB561,SEPP1,LGALS3BP,SNTA1,FAM111A,PHF7,OXCT1,PTEN,CENPJ,SGK3,PRC1,ATP8B1,SLC44A2,ERCC2,MAP3K7,SPRY2,NCOA2,SMC4,PCCB,RASGRF1,CASK,ARAP2,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,RGS9,MAMDC4,SLC25A40,AMMECR1,SERPINB5,GRIN2D,ETAA1,ARSB,CPEB2,OCLN,USP16,JARID2,ESYT2,EXPH5,LTBP1,CASP3,CAMKK1,TAF6L,DNER,CACNB4,KREMEN1,TMC1,TSEN34,SH3KBP1,ABCD4,NKAIN3,ARHGEF10L,LRRC6,ZCCHC12,DPYSL2,PHTF1,DLG1,ANKRD12,AKR1B1,SUN3,RAB20,MYH14,ARNT2,SLC39A10,PTPRE,RASGRP1,TDP1,FOPNL,RNF165,ROR1,PTGFRN,ADRBK2,TCN2,EDNRA,ARHGEF19,NEIL1,FASTKD1,IARS2,ADIPOR1,APBA2,PSMC1,PPP2R5D,MIIP,CPPED1,LRRFIP2,PEX6,ELOVL7,ATP6V1E2,SAMD9,PHLPP1,OTUD1,LRRN2,KCNN4,EBF4,FNIP1,KNTC1,RFX5,NCEH1,HP1BP3,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,GNAS,XKRX,BCAR3,TSC1,ONECUT1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,KIF12,FBXW5,GAS2L1,ZSWIM5,FAM92A1,PSME2,ABCG4,MORC4,ZMYND10,LRRC45,SLC25A48,SS18,KHNYN,FRYL,SMO,GOT1,RPN2,TWIST1,LOXL1,PDIA6,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,TAF5,KREMEN2,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,CANT1,PLXND1,SGOL1,LIFR,CBX4,ANXA3,CDS2,SORT1,POC1B,FRMD6,LRP4,FAM134A,TRMT2B,POMGNT1,FAM167A,IL17RB,IRF2BPL,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,BRD7,TRIM3,IQGAP3,SYPL1,ADAM17,RAB3B,NR4A1,GCLC,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MAP1B,KLHL2,HLA-B,C2orf70,PRCP,TADA2B,OTUB2,GLB1,SOX8,GEM,L1CAM |
| 5.305e-09 | -19.05 | oesophagus-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-carcinoma-adenocarcinoma | 13776 | 2114 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,DPP8,SLC35E4,GRM5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,XRCC6BP1,TANC1,ZNF618,TRIM7,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,SRSF9,TLL2,BCAM,KIAA1462,EPAS1,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,ARRDC1,KLF11,PARP12,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,TMX4,RHPN2,PCBP1,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,KCNS3,IRF2,SNX16,SGCE,SPATA18,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,SERPINI1,SPRY4,CCDC97,FGD1,RECQL,TBC1D1,TXNDC9,PSIP1,SH3RF2,DOPEY2,BHLHE41,AIM1,MSH2,PRKG1,ADCK2,OSTF1,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,GCC2,PRODH,KLK5,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,FOXO6,TCF25,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,ZNF704,CBX7,MAMDC2,HAPLN3,EPS8,HERC5,EFHD2,PLD2,EFNB1,FGF19,WWP2,SLC25A36,E2F7,TMEM87B,CD9,CCDC82,TTPA,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,MAN2A2,HPSE,KCNK1,ZNF165,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,SNED1,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,DCUN1D1,RAB31,NXPH4,CTSA,TOB1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,NDE1,DRP2,TRPC3,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,PARP14,MAN1A2,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ZNF230,AK3,ITM2C,TPCN1,TMX1,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,SHOX2,CYBRD1,UNKL,AGRN,GNPDA1,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,CAMK2G,IGDCC4,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,IL31RA,AOX1,STEAP2,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,CAST,SUZ12,IQGAP1,RPS6KA1,EGR3,TMPRSS4,SLC25A35,APLP2,DOK4,FICD,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,PCOLCE,SLC16A14,GPR180,PNPLA5,TMCC3,SNTA1,OXCT1,PHF7,MGAT1,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,LRRC1,NUCB1,RGS9,RCBTB2,SLC25A40,PGM2L1,ETAA1,OCLN,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,IARS2,TRIM45,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,ALPK3,RHOBTB2,KIF12,PROM2,SPC25,FAM92A1,ABCG4,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,GOT1,APIP,LOXL1,F2R,SCYL3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,ERBB2IP,BFSP1,CANT1,CDS2,SORT1,FRMD6,JKAMP,ARMC7,TRMT2B,FAM167A,SNX13,MDM1,MLPH,GALNS,BRD7,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,AK7,GRIK2,SLC25A13,RET,TRAPPC8,LACTB2,BAIAP3,SNX9,LTBP3,CARD10,CMTM6,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CRY2,WBP4,TIPARP,TIAM1,MGAT5,DSTN,TMEM98,CDA,TMEM151A,PRKAR2B,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,RIMS3,ATP5H,MEGF8,RANBP1,FBXO7,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,KANK3,DGKG,MYLIP,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,GNA11,SFXN5,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,DOCK9,ADAMTS16,NQO1,RHBDL3,FAM91A1,GRK6,REPS1,MOCS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,LRP11,RASGEF1A,TMCC2,COL6A2,SEC61B,PFKFB2,SAT1,GIGYF1,EBF2,COX20,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,SLC25A45,ZFX,PDCD10,ITGB8,FUT2,TMEM62,KNDC1,FAM20B,CST3,RAG1,PARP9,ADAMTS2,PLSCR1,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,CD81,TMEM131,PHC1,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,CTNNB1,TM9SF2,NPNT,IL6ST,MITF,SLC44A1,PSMC2,PAPSS1,THRB,KRT80,PLK1,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,RRAGD,HS6ST3,PRSS8,RMND5A,HJURP,PDCL,ADCK5,SORBS3,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,RGMB,BTNL9,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,DAG1,PTGS2,PAFAH1B3,RBL1,ABHD12,STK38,EFNA5,FAM134B,BIN1,CMAS,CPEB4,SCD5,CTSB,HAL,ERCC6L,HMGN3,GDF15,SH2D4A,FZD6,NRP2,PARM1,VPS26A,IL22RA1,M6PR,C16orf74,CD109,ALPP,FAM63A,GTF2F2,SGK1,TRIM21,HMGCL,SYK,P2RX4,HES1,MOSPD2,GUSB,PLAUR,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,CNOT2,DDAH1,FGF18,SH3BGRL2,ICOSLG,ARHGEF9,GOLGB1,ARHGEF4,LAMP1,FAM171B,VANGL1,CUL1,PDGFRL,NANS,OAT,SEPT4,ZNF823,STIM1,PIK3CA,POLL,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,TNFRSF19,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,VASN,TPST1,DAPK1,DLX4,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,APOBEC3B,CD46,C11orf84,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,CKAP5,FJX1,FUT8,ERBB3,MSH6,B3GNT2,ZWINT,PAPD7,TCFL5,FBXO9,GRTP1,CRTC2,CDK5RAP1,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,MAP1LC3B,HTR1D,ADPRHL1,SIPA1L2,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,LAP3,ACBD3,USP18,ARHGDIB,MADD,SH3GLB2,TDRD7,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,FAM81A,QSOX2,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,PODXL2,ELK3,VWA1,HEATR5A,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,WEE1,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,PTPRF,SCARB2,OSMR,DYSF,ARPC2,SERPINB1,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,KCNC4,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,ECI2,ADAM15,WWP1,MAPK11,NPTXR,SGCB,S100A6,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,DCBLD1,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,DDHD2,DUSP10,TNFRSF18,PXMP4,TLN2,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CYP26B1,CHSY3,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,LPIN3,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,GM2A,DVL2,CTH,CPD,MBP,FIGNL1,COQ10B,MYPOP,DNAJC10,PTK7,ADAMTS14,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,MAPK8IP1,BSDC1,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,ORAI2,KIFC2,NBPF3,SAV1,TP53I3,ULK2,SGPP1,AHRR,GNPTAB,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,PRRG4,ITGA3,CYR61,PIK3AP1,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,FADS2,QSOX1,MFI2,B9D2,TBC1D8B,PTPRH,TMEM133,VEZT,PKM,GLT8D2,FBXO10,STX3,DGKH,GABRD,ISM1,DCK,FGD6,NR4A2,MAP3K5,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,TMEM43,COX11,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,ATP9A,CCNJL,SEPP1,LGALS3BP,SIX4,RND1,FAM111A,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,PTGFRN,STK17B,SEC14L2,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,EGFL7,PITPNA,KLF7,ZSWIM5,IL15,SLC2A8,GMPR,MORC4,MICALL2,PATL2,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,BHLHB9,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,NOTUM,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,UBE2D2,HOXB13,GEM,LRRC57 |
| 5.414e-09 | -19.03 | neuron projection guidance | biological process | GO:0097485 | 562 | 135 | 16441 | 2455 |
MYL9,AGRN,EPHA4,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,RPS6KA2,PSMD1,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,MYH14,TIAM1,RASGRP1,RNF165,EZR,DPYSL3,PLCG1,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,PSMD7,CALM3,DUSP5,RAC2,VASP,FLRT3,COL6A1,PAK2,CACNA1D,NCAM1,WNT3A,NTN1,PSMA5,DPYSL5,RGMB,CALM1,EPHA1,DPYSL4,RANBP9,NFIB,PSMA4,EGFR,RASA1,RHOB,CDK5R1,SEMA4D,MATN2,PITPNA,EFNA1,B4GAT1,ARPC2,JAK3,TRPC3,SEMA3A,RPS6KA3,KLF7,SPRED1,RPS6KA1,PSME2,ERBB2,RASGRP3,PDGFA,ARTN,DAB2IP,EPHB4,DLG3,RASGEF1A,ETV4,SEMA3B,FRS3,COL6A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,IRS2,EPHA10,FYN,JAK1,PSMD3,EFNA5,NRG1,SPTBN5,PLXND1,COL9A3,ARHGEF11,ARHGEF7,PSMD10,COL4A5,EFNB1,FGF19,ITGA2B,NRP2,NEO1,GBX2,RND1,KIF5B,ANK1,BMP7,ERBB3,CAMK2G,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,RAPGEF2,GRIN1,YES1,ABLIM2,CNTNAP1,FGFR2,FGF18,NR4A3,PGRMC1,RYK,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 5.414e-09 | -19.03 | axon guidance | biological process | GO:0007411 | 562 | 135 | 16441 | 2455 |
MYL9,AGRN,EPHA4,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,RPS6KA2,PSMD1,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,MYH14,TIAM1,RASGRP1,RNF165,EZR,DPYSL3,PLCG1,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,PSMD7,CALM3,DUSP5,RAC2,VASP,FLRT3,COL6A1,PAK2,CACNA1D,NCAM1,WNT3A,NTN1,PSMA5,DPYSL5,RGMB,CALM1,EPHA1,DPYSL4,RANBP9,NFIB,PSMA4,EGFR,RASA1,RHOB,CDK5R1,SEMA4D,MATN2,PITPNA,EFNA1,B4GAT1,ARPC2,JAK3,TRPC3,SEMA3A,RPS6KA3,KLF7,SPRED1,RPS6KA1,PSME2,ERBB2,RASGRP3,PDGFA,ARTN,DAB2IP,EPHB4,RASGEF1A,DLG3,ETV4,SEMA3B,FRS3,COL6A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,IRS2,EPHA10,FYN,JAK1,PSMD3,EFNA5,NRG1,SPTBN5,PLXND1,COL9A3,ARHGEF11,ARHGEF7,PSMD10,COL4A5,EFNB1,FGF19,ITGA2B,NRP2,NEO1,GBX2,RND1,KIF5B,ANK1,BMP7,ERBB3,CAMK2G,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,RAPGEF2,GRIN1,YES1,ABLIM2,CNTNAP1,FGFR2,FGF18,NR4A3,PGRMC1,RYK,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 5.661e-09 | -18.99 | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | MSigDB lists | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | 325 | 87 | 17758 | 2588 |
CCNI,CASP3,TXN,NQO1,TRIP10,SUZ12,NDRG1,APOO,RASGRP3,IL13RA1,FTH1,PLXNA1,BCAP31,CCND1,ZFYVE16,DPYSL2,IL6ST,VAT1,TFG,EGLN3,GM2A,SEPHS1,LAMP3,CYP1B1,LAMP2,DOCK4,FOXJ2,ACO1,SLC11A2,RAB38,LHFPL2,MAP3K6,ADRBK2,OPTN,DUOX1,FASTKD1,JAK1,RBM47,RAB11FIP1,MAOA,TRAF5,HSPB1,ST3GAL1,GCLM,CDS2,MPZL1,PPP1R12A,CD63,SDC4,C6orf106,SLC1A3,C3orf18,DUSP5,SGPL1,TNS3,SPP1,LYPD3,TMEM51,TPST1,CD9,TMBIM6,FAM69A,WBP5,GFPT1,LITAF,GGH,RUNX3,CYB5A,CD83,IL1R1,NCOA3,BTG1,PVRL2,NAT1,SPINT2,NETO2,NR4A3,MDH1,LRRK1,ATP1B3,LTBP2,ATP6V1C1,FZD5,NDE1,TBC1D4,CD81,ABCG1 |
| 5.726e-09 | -18.98 | PH | smart domains | SM00233 | 278 | 82 | 9131 | 1455 |
PLEKHG3,FAM129B,TEX2,PHLDA1,SPTB,ARHGEF16,ACAP2,ARHGAP42,ELMO2,DOK4,OSBPL3,PLCG2,DNM2,DAB2IP,RTKN2,OSBPL7,TIAM1,AKT1,SNTB2,PLEKHO1,ANLN,ADRBK2,ARHGEF26,ABR,PLEKHB1,IRS2,PLCG1,PLCH1,PLEKHG6,ARHGEF19,MPRIP,TRIOBP,PLEKHG1,SPTBN5,GAB1,FGD1,ARAP3,FARP1,ARHGEF3,ARHGEF11,PLEKHJ1,ARHGEF7,CIT,RASA2,PLD2,TEC,SBF1,PHLPP1,DOCK11,ARHGEF40,SNTA1,ADRBK1,RALGPS2,MCF2L,EXOC8,PLEKHF1,CADPS2,FARP2,RASGRF1,PLEKHA6,ARAP2,ARHGEF28,PHLDB3,SPATA13,PLEKHA7,SNTB1,FAM109A,RASA1,ARHGAP24,DGKH,SWAP70,PLEKHH2,APPL2,ARAP1,FGD6,PLD1,AFAP1,ARHGEF9,DEF6,NGEF,DOCK9,ARHGEF4 |
| 6.005e-09 | -18.93 | negative regulation of protein modification process | biological process | GO:0031400 | 584 | 139 | 16441 | 2455 |
CASP3,PPP4R4,IBTK,DNAJC3,NDRG2,PSME1,CCNB1,PHF1,TP73,CALM2,CDKN2C,PSMD1,CTNNB1,RGS3,PSMC2,DLG1,DUSP10,CRY2,PLK1,TNIP1,ITCH,PBK,EZR,PRKAR2B,PIAS3,ENPP1,CAMK2N2,LIMK1,TRAF3IP1,PPP2R4,SPRY4,HSPB1,F2RL1,PSMC1,LMTK3,CDKN1C,DNAJB2,UBASH3B,PSMD7,CALM3,FBLN1,DUSP5,SH3RF2,MECOM,TFAP4,RB1,IGF1R,FBXO7,PAK2,SORL1,PSMA5,SOCS5,CALM1,HMG20B,EPHA1,ILK,KDM3A,PSMA4,RANBP9,PRKAG2,SEMA4D,PLPP3,STK39,CTBP1,XDH,DRD1,SPRED1,NF2,FOXM1,PSME2,CTDSPL,P2RX7,SYTL2,PER2,SVBP,DACT1,CDKN1B,TWIST1,DAB2IP,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,SIRT1,CAMSAP3,BAG4,AKT1,DMTN,CDC20,PKMYT1,DUSP4,DAG1,C3orf33,SOCS3,DNAJC10,FYN,PTPRJ,STK38,CORO1C,PSMD3,WWTR1,RGS14,PRKAR1A,CTDSP1,ARFGEF3,FARP1,PINK1,PSMD10,PKN1,TRIB2,GSTP1,TIPRL,SH2D4A,CD109,SNTA1,PTEN,BMP7,BAX,TRIM21,H2AFY,BUB1,HEXIM2,SPRY2,CRTAP,DUSP1,PSMB4,GCLC,MAPK8IP1,CDK5RAP1,LEMD2,SWAP70,ARRB1,LRRK1,GPER1,UBE2C,HIPK3,PKIA,JARID2 |
| 6.099e-09 | -18.92 | regulation of cyclin-dependent protein kinase activity | biological process | GO:1904029 | 122 | 44 | 16441 | 2455 |
CCNE2,CCNC,CASP3,CDKN1C,DNAJC3,HERC5,PSMD10,CCNL1,TRIB2,PDGFB,STIL,CCND1,TFAP4,CDKN2C,DIRAS3,CCNA2,PTEN,FBXO7,CKS1B,CDKN1B,HEXIM2,PIM1,CDKN2D,HSPA2,SOCS5,CKS2,CHP1,PLK1,ADAM17,PSRC1,AKT1,RGCC,PKMYT1,CDC25C,MAPK8IP1,EGFR,CDK5R1,SOCS3,CDK5RAP1,CAMK2N2,CCNB3,PKD2,UBE2C,PKIA |
| 6.340e-09 | -18.88 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_UP | 191 | 59 | 17758 | 2588 |
SERPINE2,LGALS3,S100A11,GNPDA1,GCAT,DAP,NDRG1,CDCA3,CDCA8,KIF23,LACTB2,REPS1,KCTD9,DAPK2,TOP2A,CDKN2C,CCNA2,PRC1,CD9,BRD7,CKS1B,KIF22,BUB1,AK3,CTSD,CDKN2D,CLIP2,SNX10,S100A13,LAMP2,PQLC3,S100A4,CRIP2,LITAF,FHL2,CAPNS1,ARHGDIB,AURKB,PRRC1,CCNF,ANLN,ALCAM,CDC25C,CDK1,GABARAPL1,GNAS,CARHSP1,CASP7,JAK1,TWSG1,CDCA5,DBI,AURKA,KPNA2,CTSA,CCNB2,E2F8,ACOT7,XDH |
| 6.430e-09 | -18.86 | KIM_MYCN_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYCN_AMPLIFICATION_TARGETS_DN | 92 | 36 | 17758 | 2588 |
LMO7,RECQL,INPPL1,CEP70,TTC39B,EPAS1,NDRG1,RASA2,CCNL1,CAMK1D,B4GALT4,TMEM19,BARD1,PPP2R3A,APOBEC3B,FAM111A,CPNE2,TMEM87B,ITGB8,ZDHHC23,PIK3CD,MAP3K7,EPB41L5,GCA,TMEM98,HMG20B,YES1,GOLT1A,OPTN,IRX3,DNAJC10,INSR,MYLK,PLEKHG1,KLF5,GOLGB1 |
| 6.454e-09 | -18.86 | WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN | MSigDB lists | WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN | 100 | 38 | 17758 | 2588 |
S100A11,CAST,ARL4C,SLC1A3,RAB6A,NUCB2,DUSP5,RABGGTA,OXCT1,STIM1,TSPAN6,SLC16A6,KCNK5,PPP4R1,ALDH1A3,PCYOX1,FUT1,WWP1,IGFBP2,TIAM1,GM2A,EPHX1,SHMT1,MAPKAPK3,STAT4,AMFR,CR2,KIF1C,CAPNS1,STK17B,PGF,ENDOD1,MOSPD3,NCOA3,STK38,PITPNA,ADIPOR1,NRBP1 |
| 6.649e-09 | -18.83 | cell development | biological process | GO:0048468 | 1717 | 339 | 16441 | 2455 |
ACVR1,RET,HEXB,CACNA2D2,GATA3,NRG2,PSME1,PLXNA1,SEPT4,CCNB1,FAM101B,PICK1,CALM2,TP73,NPM2,WEE1,PSMD1,TGFBR3,PAQR5,DNM2,SEMA3G,PACSIN1,ZBTB18,TIAM1,SMARCA2,CASP9,TFAP2C,LOXL2,ULK2,ARF4,ARHGEF26,PLCG1,AREG,LIMK1,TBX1,TMOD2,UNC5B,F2RL1,SEMA6B,SCN5A,KLF2,CDKN1C,TMTC3,SOX9,SLC1A3,MERTK,KIAA1161,LMNA,RAC2,FRY,CYR61,FLRT3,MEGF8,MSH2,PRKG1,CACNA1D,NCAM1,DGKG,PAQR7,EPB41L5,REC8,CALM1,FHL2,KIF20B,EPHA1,ILK,ANTXR1,KDM3A,DPYSL4,NFIB,PSMA4,STX3,RHOB,RASA1,PTPRF,SEMA4D,HTT,MATN2,FAM83D,CLMN,AURKA,NR4A2,EFNA1,B4GAT1,GDF11,ARPC2,HOOK1,TRPC3,RPS6KA3,EHD1,SPRED1,GRHL2,ST14,NDRG1,IQGAP1,RPS6KA1,BCL2L1,PRKACA,CDH1,DACT1,DAB2IP,EPHB4,PDE4D,ACSL4,RASGEF1A,DLG3,ETV4,SEMA3B,CAMSAP3,COL6A2,FZD4,DMTN,SLC11A2,PRKCQ,PYGO1,ALCAM,FZD7,EPHA10,IRS2,FYN,JAK1,SHROOM3,CORO1C,AXL,SLC9A6,KLF5,NRG1,COBL,PRKAR1A,WASF3,CTHRC1,FARP1,SDC4,CCM2,FLOT1,PBX3,PLPPR4,SPR,FGF19,EFNB1,SIX4,ICAM1,RND1,NEO1,ANK1,IGSF9,PTEN,CST3,CD9,BAX,ADAM15,ATP8B1,ERBB3,ERCC2,SGCB,S100A6,FARP2,RASGRF1,B3GNT2,ARHGEF28,FMN1,RAPGEF2,GRIN1,VAMP3,C1GALT1C1,DIAPH2,YES1,ABLIM2,CNTNAP1,PITX2,FGFR2,NR4A3,RYK,GRIN2D,ITGAV,LRRK1,FZD5,OSR1,SHOX2,FOXA1,RGMA,EXPH5,MYL9,CASP3,EMX1,UGT8,EPAS1,AGRN,CUL4B,EPHA4,ARFGEF1,F11R,MPP5,DNER,SDC1,PDGFB,CACNB4,TMC1,SPTB,RPS6KA2,CTNNB1,SHC3,DPYSL2,IMPAD1,PSMC2,DLG1,TRPC1,NTN4,MYH14,CTTN,BTBD3,RASGRP1,ATL1,SOD1,CELSR2,RNF165,EZR,DPYSL3,EDNRA,HS6ST1,MAP2,TDRD7,PSMC1,MYL12B,USH1C,RUNX2,BVES,RASA2,ETV5,PSMD7,CALM3,CNTNAP2,DUSP5,BMP2,RB1,VASP,IGF1R,LRRN2,GATA2,FAM20C,PAK2,COL6A1,PRKCI,NTN1,WNT3A,PSMA5,DPYSL5,RGMB,SCRIB,RANBP9,CDK5R1,EGFR,ONECUT1,FA2H,PVRL2,MFSD2A,PITPNA,AKIP1,SEMA3A,JAK3,RARG,KLF7,DRD1,PAX6,IL15,PSME2,HDAC11,ERBB2,COL18A1,RASGRP3,MICALL2,PDGFA,ARTN,KIF14,FRYL,LHX6,BCL6,SMO,TWIST1,HSPA2,SULF2,FRS3,AKT1,S100A4,MYL12A,DAG1,ARHGAP35,HSF4,RTN4RL1,BFSP1,PSMD3,PTBP3,SPTBN5,EFNA5,PLXND1,LIFR,COL9A3,ARHGEF11,ARHGEF7,FRMD6,CIT,LRP4,PSMD10,TGFBR1,GDF15,COL4A5,JAG2,NRP2,ITGA2B,GBX2,KIF5B,CDK16,BMP7,UBE2J1,TFAP2A,SGK1,ACTA2,RPGR,CAMK2G,HES1,RHOA,PSMB4,WNT10B,ASPM,STMN3,RUNX3,FNDC3A,BBS2,MAP1B,FAT4,RAP2C,SPINT2,FGF18,PGRMC1,HOXB13,SOX8,PLOD3,L1CAM,NGEF |
| 6.799e-09 | -18.81 | Ras guanyl-nucleotide exchange factor activity | molecular function | GO:0005088 | 127 | 45 | 16491 | 2452 |
PLEKHG3,ARHGEF3,FARP1,ARHGEF11,ARHGEF7,RASGRP3,SBF1,DOCK11,ARHGEF40,DENND2D,RIC1,ARHGEF16,EPS8L2,ARHGEF10L,ST5,ARHGEF37,MCF2L,KNDC1,RASGEF1A,TIAM1,ALS2CL,RASGRP1,FARP2,RASGRF1,ARHGEF28,RAPGEF2,DENND1B,SPATA13,RAB3IP,ABR,ARHGEF26,PLEKHG6,ARHGEF19,RCBTB2,MADD,RIN3,PLEKHG1,FGD6,ARHGEF9,RAB3IL1,NGEF,DOCK9,ARHGEF4,FGD1,DENND5B |
| 6.912e-09 | -18.79 | binding | molecular function | GO:0005488 | 13878 | 2156 | 16491 | 2452 |
HEXB,TGOLN2,FAM46C,SPSB1,GRM5,LYPD5,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,NEK4,UXT,KDELR3,TFAP2C,PNKD,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,SEC61G,ITGA6,MTL5,RAB23,GPSM2,FAM21C,ATG4A,RAC2,ZCCHC17,FBXL14,MAP3K9,USP1,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,PPP6R1,MCCC2,PYM1,FHL2,ELK1,NPHP3,DPYSL4,PCTP,PLIN5,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,RNF224,C5orf30,MAPK4,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,SEPT6,PTPN9,VPS4B,HTATIP2,SYP,XRCC6BP1,GTF2A2,SNX12,TRIM7,ZNF618,NFIX,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,CTHRC1,HSP90B1,MPZL1,BACE1,DCAF7,ESRP1,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,CTSZ,ZNF219,HDGFRP2,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,KLC3,BAX,FAM102A,IGFBP2,MED22,ACBD5,PVRL4,TACC1,PIK3R1,DUSP23,NUB1,PGBD1,RAB3IP,PIM3,CNTNAP1,RAB11FIP2,SYT7,FAM3C,PLA2G15,FBXO44,WDR45B,SRSF9,ACOT7,TLL2,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,RPS6KA2,NUP210,RABEP2,P4HB,PAPL,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,KLF11,RUNX2,LMTK3,PARP12,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,TNS3,TIMP1,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SELK,AHCY,PIM1,NTN1,DPYSL5,PCDH1,EMC2,STRADB,ZSCAN12,PDK3,PRX,CDK5R1,COL13A1,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,SMCO4,HOXB7,PCBP1,BCAP31,IER3,KMT5C,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,PTPRJ,IDE,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,UBE2J1,IL17RA,ALDH7A1,CPLX1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,TXN,PNISR,SSH1,HSPG2,LGR4,TMEM86B,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,HELZ2,TYMP,OSBPL3,PALD1,FOSB,IRF2,SNX16,HYLS1,SPATA18,BNIP3L,KIF13A,ANKRD10,SH2D3C,BMP1,NFKBIZ,SPRY4,F2RL1,FGD1,RECQL,CDKN1C,TBC1D1,TXNDC9,PSIP1,SH3RF2,C9orf69,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,ADCK2,PRKG1,TMEM51,OSTF1,CACNA1D,MAST4,SYTL3,TRAK2,GFPT1,GCC2,PRODH,KLK5,CEP89,ADCK3,DCHS1,PYGL,EPHA1,ATP8B3,MMP15,PLEKHH2,TJP3,AGBL5,PIAS2,APPL2,SFMBT1,CDK18,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,NAGA,MED30,SEMA3B,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,PYGO1,PKMYT1,ASB13,CBL,FZD7,CEP162,ACAD10,NGFRAP1,TRIOBP,ZNF704,CBX7,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,SPDL1,FGF19,EFNB1,WWP2,SCML1,E2F7,RNF128,GNB5,CD9,CITED2,TTPA,FARP2,PDGFC,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,CPTP,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,ESPL1,DEF6,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,EPCAM,ZFYVE16,HSF2,CDKL5,TRPC1,ASH2L,MYRIP,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,TYSND1,MAN2A2,HPSE,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,ADAMTSL4,DUSP5,NOXA1,PFKL,OCRL,COL6A1,PRKCI,BRAT1,LIMCH1,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,STEAP1,RANBP9,SOX13,UAP1,SPAG7,RAB31,DCUN1D1,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,DYNLRB1,SORBS1,PAX6,PDIA5,COL18A1,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CHP1,SOAT1,RFK,MRPS35,GLO1,CDC25C,PDHX,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ARHGEF7,TGFBR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,RGCC,LEPR,ENDOD1,ARHGAP24,CTSL,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,UACA,ARRB1,GRAMD1C,ZMIZ1,ACACB,IL15RA,TRIM5,DNAJC3,CACNA2D2,SMARCAL1,NRG2,CNTROB,MORF4L2,SYTL4,BARD1,PHF1,DAPK2,ZYX,AP1M2,TGFBR3,CYP2S1,SLC46A1,KLF3,SEMA3G,TUBA4A,NWD1,TNIP1,RNF11,MTRF1L,F12,MYOM1,CYP4F3,TRIM47,CAMK2N2,WDR11,DNM1L,MYLK,AGFG2,LSM14B,ARF6,ALDH6A1,TMTC3,SOX9,LMNA,DNPEP,NEK2,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,ILK,DCP2,CYB5A,STK17A,DHX32,NAAA,NCOA3,SEMA4D,HTT,SETD3,ITPR1,AURKA,ALG2,B4GAT1,MAL2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,TMSB15A,ACTR8,ETNK1,RGS20,NUF2,IL13RA1,KTN1,CCND1,SCNN1A,RNF220,ACSL4,RAB27B,CDKN2D,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,RAB38,PEX5,STX10,WWTR1,TRABD2A,PDXK,RGS14,ARNT,TNRC6C,TAOK2,NKX3-1,RBM24,MAN1A2,RASSF7,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,DTX3L,CAPN2,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,CCDC6,ATXN7L3,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,EPHA4,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,ANO4,TRAM1,DDX59,NEB,PCGF5,MCTP1,ERP44,ESYT1,ANLN,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,ZCCHC24,HLA-F,UBASH3B,DOCK11,BMP2,GATA2,EXOC8,MDFIC,PLCB2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,ZC2HC1A,H1F0,CSF1,ATP1B3,CTBP1,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,CYP26A1,C1orf116,CDK14,RAD23A,GYS1,EGLN3,SIRT1,TIMP2,TCEB2,S100A4,CDC20,DUOX1,RTN4RL1,ATP1A1,PSMD3,RPL22,AIFM3,ZNF701,COPG1,ZC3HC1,MAN2B2,PACSIN2,TRAPPC10,CD63,ADGRG1,RUSC2,DAP,GNE,SWI5,PSMD10,NKRF,SIRPA,PPP2R3A,CEP97,BUB1,HEXIM2,FAIM,CAMK2G,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,CARD19,FXR2,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,TWSG1,ZNF214,NETO2,PGRMC1,PPP2R3C,GUCD1,NDFIP1,UBE2C,DIS3L,ACVR1,PPP4R4,ATP8A1,KLC2,CCNB1,RIC1,CTGF,ZFP36,IL31RA,STEAP2,AOX1,TFG,RCAN3,SMYD5,LAMP2,LOC81691,SNTB2,PBK,HSPA12A,CASP9,TNS1,PIF1,GALNT7,CCNF,HLF,RBM47,PLK2,PTER,TBX1,NKD1,SARAF,DHTKD1,EIF4EBP2,TMEM8B,TRAF5,LZTS1,DLAT,KLF2,CDK17,MRPL44,DGKQ,CALB2,ADO,C6orf106,KIF23,SLC1A3,NOTCH2,MECOM,SNX18,NECAB3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,ZNF84,MICB,AMER1,PIP4K2C,FAM133B,CYFIP2,KDM3A,RASA1,FAS,PRKAG2,CSNK1G1,NAB2,TCEAL4,PCDH19,NRBP1,PKD1L2,IRF1,PLA2G4A,ELK4,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,RNF182,EGR3,NUDT12,GNB2,TMPRSS4,APLP2,FAM46A,FICD,DOK4,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,H2AFV,ZNF469,NIN,OSBPL2,JAK1,STK26,KIAA1804,NRG1,RAB29,B4GALT3,ATMIN,NUDT6,ARHGEF3,PCOLCE,ARL4C,CDCA3,APOBEC3H,TEAD3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,PRC1,SGK3,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,SHMT1,CASK,MPP1,TEF,VAMP3,FURIN,C1GALT1C1,NUCB1,RGS9,PRDX3,RCBTB2,CSTF2,PGM2L1,CPEB2,OCLN,NMRK1,FLYWCH2,CAMKK1,HEBP1,UBE2Z,TAF6L,CACNB4,DENND2D,KREMEN1,SH3KBP1,ABCD4,MAGOHB,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,SUN3,RAB20,NFU1,MYH14,PTPRE,TRIM8,ASCL5,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,PIFO,LRRFIP2,PEX6,ASL,PHLPP1,KCNN4,EBF4,SIMC1,HP1BP3,GYLTL1B,HMG20B,EGFR,GNAS,FECH,TSC1,ONECUT1,PLPP3,NFKBIA,CDCA5,RHOBTB2,ALPK3,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SLC25A48,SS18,KCTD15,KHNYN,ZDHHC12,SMO,GOT1,STEAP3,RPN2,APIP,F2R,LOXL1,SCYL3,FRS3,MAP3K3,GCA,ZNF525,IGSF8,ERBB2IP,BFSP1,CANT1,CCDC24,SORT1,JKAMP,FRMD6,ARMC7,TRMT2B,FAM167A,IRF2BPL,SNX13,MLPH,GALNS,CKS1B,BRD7,RAB3B,CENPC,PHLDB3,MBNL3,OGDHL,SPAG1,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,ZNF596,SNPH,IBTK,AK7,GRIK2,SLC25A13,RET,TRAPPC8,LACTB2,BAIAP3,ISOC2,SNX9,LTBP3,CARD10,CMTM6,ZNF275,CDKN2C,NPM2,NAPG,MUC4,CLDN4,CRY2,WBP4,RNF26,TIPARP,TIAM1,DSTN,CDA,PRKAR2B,RNF19B,GINS4,ARF4,PLCG1,CARHSP1,ENPP1,ATP7B,CELF5,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,MEGF8,RANBP1,FBXO7,CADPS2,SLAIN2,MYDGF,ALPK1,FAM84B,ZMYM1,MYLIP,ULBP2,DGKG,PHKG2,PAQR7,MAPKAPK3,SHARPIN,ERO1A,KIF20B,GNA11,PSMA4,IL1R1,FNTA,S100A5,CLMN,STK39,CFAP20,TMEM159,CBX5,NUP58,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,INPP5D,PTTG1,RHBDL3,APOO,GRK6,MVB12B,REPS1,MOCS1,APPBP2,RCN1,CDH1,SH3BP1,DLG3,LRP11,ETV4,SNX10,TMCC2,MX1,COL6A2,SEC61B,PFKFB2,SAT1,EBF2,GABARAPL1,ALDH3B1,CCNB3,ISOC1,MAPK12,TCAF1,MZT1,GCAT,TRAF2,IFT27,SGPL1,CTNNBIP1,ZFX,PDCD10,ITGB8,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,OPLAH,PLSCR1,CXorf57,UBE2A,AK4,RPL12,PROM1,LDLRAP1,PLOD2,DBI,NR4A3,SSNA1,ITGAV,OSR1,CMPK2,CD81,PHC1,LMCD1,DNAJB11,GALM,ITPR2,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,CTNNB1,NPNT,ARL1,IL6ST,PASK,MITF,PSMC2,PAPSS1,SCARA3,KRT80,THRB,PLK1,KCNIP3,CELSR2,CCBL2,NKAIN1,EAF2,KDM4D,TNS4,PLEKHG6,KLF12,ZNF367,KPNA2,MYL12B,TC2N,RRAGD,PRSS8,RMND5A,HJURP,LGALS3,DNAJB2,PDCL,ADCK5,SORBS3,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,CKAP4,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,RASGRP2,FOXD2,FA2H,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,EMP2,STIL,SYTL2,TMSB15B,PDGFA,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,STK38,MMP17,EFNA5,ARHGAP4,CTDSP1,FAM134B,BIN1,DYRK3,CPEB4,TOR4A,SCD5,CTSB,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,NRP2,SH2D4A,FZD6,IL22RA1,VPS26A,M6PR,CD109,ALPP,CDK16,TFAP2A,FAM63A,GTF2F2,TRIM21,SGK1,HMGCL,SYK,WBP5,P2RX4,HES1,HMGN5,GUSB,PLAUR,CRIP2,STMN3,PRICKLE1,BBS2,RNPEP,TXNDC11,DGKE,USP6,BCL10,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ICOSLG,GOLGB1,ARHGEF4,FAM171B,LAMP1,VANGL1,TSC22D3,CUL1,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ZBTB18,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,THEMIS2,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,PDXDC1,MESDC2,CALR,ZNRF2,VASN,RPL39,DAPK1,DLX4,ZNF117,SOCS5,CALM1,WHSC1,NPC2,JADE2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,MATN2,C1orf21,ZDHHC20,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,SPRED1,GPR107,REPS2,CAPN12,DLGAP5,CCDC110,NDRG1,RALBP1,THRA,FTH1,BLCAP,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,CD46,APOBEC3B,RALB,EPHB4,RNASEH2A,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,RAD17,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,EFCAB14,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,PBX3,CBLL1,NES,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,FOS,CDK5RAP1,CRTC2,TIMP3,SEC14L4,ABCB1,FZD5,MELK,COMMD5,SLC8B1,ERP29,MAP1LC3B,ECI1,HTR1D,ADPRHL1,RAB15,SIPA1L2,SIVA1,CTTN,SP5,STK35,CERS2,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,GPRC5B,MADD,SH3GLB2,TDRD7,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,PPP1R12A,PYROXD2,ASB9,TEC,SPP1,FAM20C,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,PODXL2,ELK3,VWA1,PDIK1L,RHPN1,INSR,TMEM30A,SH3BP4,JAK3,SHROOM2,COL16A1,APOL2,DRD1,CCNE2,LMO7,FAM214B,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,CYP4F11,REEP1,ECE1,ETHE1,SEPHS1,UPF3A,PTPRU,C3orf52,CD40,TMTC2,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,CIT,SERPINB9,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,H2AFY,ACTA2,KANK2,CLIP2,RPGR,RBMS2,WNT10B,NADK2,RUNX3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CTSV,CSGALNACT1,MCUR1,PLOD3,CEP41,AHR,RAB3IL1,ABCG1,CD33,DOC2A,ADD1,TRIM24,MRPS15,XIAP,FBXO2,DHX8,IL18,KIF26A,CA8,EPDR1,CALM2,TP73,WEE1,DNAH6,CABP1,ALDH1A3,PPP1R16A,TUBG1,TINAGL1,PIK3CD,MANF,ACOX2,APOBEC3G,ERAP2,SMARCA2,VPS11,SH3BGRL,SPRTN,LOXL2,ICMT,SLC44A3,PGF,LIMK1,MAP3K11,MRPS28,SERPINB6,GAB1,E2F8,HOXC13,NFKBIE,NUAK1,CYP2J2,STRN4,ZNRF3,MERTK,RAVER2,ELF3,GNS,WDFY1,CD22,PRICKLE4,ZIC5,NCAM1,UFD1L,CALCRL,PLS1,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,OSMR,DYSF,MDH1,ARPC2,RPS6KA3,CSRP2,XDH,MTM1,PAPSS2,GRHL2,TUBB4B,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,PXYLP1,IRS2,TTC12,SIPA1L1,INPP4B,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,TMA16,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,WWP1,MAPK11,NPTXR,S100A6,CRTAP,AMOTL2,MOB4,CTNNAL1,FMN1,BCL9,GRIN1,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,HMGA1,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,CUL4B,SUDS3,NDC80,MCCC1,CDIPT,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,PXMP4,TLN2,MYBL1,S100A13,ZNF462,CD55,ING1,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,CDK1,OPTN,PLCH1,MSL1,WIPI1,PRKCDBP,CTNND1,TTC9,EPB41L4A,PXDC1,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,PAK2,TMEM8A,PSMA5,ABCC1,CYP26B1,CHSY3,TCF7,IFIT3,SMN1,MAPKAPK2,PVRL2,ITGA7,PRPS2,LTBP2,IFI6,RNF146,UPF3B,FOXM1,P3H2,ZNF28,CCNL1,SDF4,PER2,PLCG2,LHX6,SRR,DVL2,CTH,CPD,MBP,FIGNL1,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,POMGNT2,CNEP1R1,CMTM4,GSDMD,MACC1,SELL,GABRG2,JAG2,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,FAH,DLGAP1,HMMR,PSMB4,PPARA,TRIM35,CAPNS1,NPDC1,BORA,MAPK8IP1,SCRN2,PRDX4,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CFAP77,TMEM248,CLIP4,PKD2,ACADM,SUN1,GAA,TTC39B,TAP1,GATA3,PLA2G16,FAM101B,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,PACSIN1,ORAI2,KIFC2,MGAM,AGO4,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SORL1,TNFRSF12A,CD70,RIMS2,TSPAN33,MFI2,B9D2,TBC1D8B,PTPRH,ANO6,CFAP206,VEZT,PKM,FBXO10,STX3,DGKH,GABRD,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,IFIT1,TMBIM1,MYO5B,CDKN2AIP,SEC23A,TMEM43,CAPN6,DMTN,COX11,SLC11A2,LINC01588,SP4,CMTM7,EPHA10,FYN,ZNF641,PPP2R5A,STAT1,PPP1CB,SLC27A1,KLF5,MLKL,ZC3H12B,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CYB561,SEPP1,SPR,SIX4,RND1,FAM111A,C16orf59,PPP1R10,PTEN,CENPJ,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,PARP4,AMMECR1,SERPINB5,GRIN2D,GPER1,ARSB,NCAPG2,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,LTBP1,ST13,KIF2C,DNER,TSEN34,CHPF,GRHL1,ZCCHC12,DPYSL2,DLG1,CAPG,POF1B,RP2,ARNT2,TECR,RASGRP1,FGFR1OP2,OLFML2A,ATL1,TDP1,SOD1,RNF165,PTGFRN,STK17B,SEC14L2,NEIL1,ARHGEF19,FASTKD1,ADIPOR1,APBA2,MIIP,PSMC1,GRN,ELOVL7,ATP6V1E2,SAMD9,AIM1L,ZNF432,CA2,FXYD5,FNIP1,ZNF692,KNTC1,RFX5,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,BCAR3,NUDT16,CGREF1,PAPD5,PITPNA,EGFL7,FBXW5,KLF7,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,GMPR,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,ADORA1,KIAA0319,TRIM3,MXD3,HSPA13,IQGAP3,SUN2,ADAM17,GCLC,NR4A1,ASPM,POLD3,MAP1B,KLHL2,HLA-B,MARC1,HNRNPH2,PRCP,DHRS2,TADA2B,UBE2D2,HOXB13,GEM |
| 6.913e-09 | -18.79 | GSE22886_CTRL_VS_LPS_24H_DC_DN | MSigDB lists | GSE22886_CTRL_VS_LPS_24H_DC_DN | 196 | 60 | 17758 | 2588 |
DDX58,CASP3,TXN,IL15RA,VANGL1,PSME2,HLA-E,HLA-F,TAP1,SOD2,GMPR,UBE2Z,CALM3,HERC5,BTN3A1,SAMD9,HERC6,DUSP5,LGALS3BP,ICAM1,HLA-A,H1FX,CALM2,BTG3,TYMP,GYS1,IFIT1,OAS3,NFKB2,RASGRP1,GPX4,LAMP3,DUSP1,P2RX4,TGIF1,SEC61B,TNIP1,RIPK2,IFITM3,LAP3,USP18,CALM1,NFE2L1,PTGER4,BTN3A2,PRKAR2B,IFIT3,CD83,HLA-B,BTG1,CDCA4,CASP7,C19orf66,NMI,STAT1,NR4A3,IRF7,IFIH1,IFI6,CSRP2 |
| 6.945e-09 | -18.79 | neuron development | biological process | GO:0048666 | 1007 | 216 | 16441 | 2455 |
MYL9,EMX1,UGT8,AGRN,CUL4B,RET,EPHA4,ARFGEF1,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,TMC1,PICK1,TP73,CALM2,WEE1,PSMD1,RPS6KA2,SHC3,DPYSL2,PSMC2,DLG1,DNM2,TRPC1,NTN4,CTTN,MYH14,PACSIN1,ZBTB18,TIAM1,BTBD3,RASGRP1,ATL1,SOD1,CELSR2,RNF165,EZR,ULK2,ARF4,DPYSL3,HS6ST1,PLCG1,AREG,MAP2,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,USH1C,CDKN1C,RASA2,PSMD7,CALM3,CNTNAP2,SLC1A3,DUSP5,RB1,RAC2,VASP,IGF1R,FRY,LRRN2,GATA2,MEGF8,FLRT3,PAK2,COL6A1,PRKG1,PRKCI,CACNA1D,NCAM1,WNT3A,NTN1,DGKG,PSMA5,DPYSL5,RGMB,CALM1,SCRIB,KIF20B,EPHA1,ILK,DPYSL4,NFIB,PSMA4,RANBP9,STX3,RHOB,EGFR,RASA1,CDK5R1,PTPRF,SEMA4D,HTT,MATN2,CLMN,AURKA,PITPNA,NR4A2,EFNA1,B4GAT1,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,KLF7,DRD1,EHD1,SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,RASGRP3,MICALL2,PDGFA,ARTN,CDH1,DACT1,FRYL,LHX6,DAB2IP,EPHB4,ACSL4,RASGEF1A,DLG3,ETV4,SEMA3B,FRS3,CAMSAP3,COL6A2,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,EPHA10,IRS2,FYN,RTN4RL1,JAK1,SLC9A6,PSMD3,SPTBN5,NRG1,EFNA5,PLXND1,LIFR,COBL,CTHRC1,COL9A3,FARP1,ARHGEF11,CIT,ARHGEF7,LRP4,SDC4,FLOT1,PBX3,PSMD10,COL4A5,PLPPR4,SPR,FGF19,EFNB1,ITGA2B,NRP2,RND1,GBX2,NEO1,KIF5B,ANK1,IGSF9,PTEN,CDK16,BMP7,ATP8B1,SGK1,ERBB3,RPGR,S100A6,CAMK2G,FARP2,RASGRF1,HES1,B3GNT2,RHOA,ARHGEF28,PSMB4,FMN1,RAPGEF2,GRIN1,STMN3,RUNX3,YES1,ABLIM2,MAP1B,CNTNAP1,FAT4,FGFR2,FGF18,RYK,PGRMC1,NR4A3,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 7.139e-09 | -18.76 | MODULE_139 | MSigDB lists | MODULE_139 | 73 | 31 | 17758 | 2588 |
DPYSL5,GCA,BCAM,BLVRB,GATA3,TFAP2C,TP53I11,CRABP2,AIF1L,PDGFB,ARHGEF16,RHOB,CYB5A,SYTL2,ELF3,EPCAM,SCNN1A,MLPH,CDH1,TJP3,BMP7,BDH1,SPINT2,CLDN4,ANXA9,MAL2,ERBB3,SULT2B1,ISOC1,OCLN,FOXA1 |
| 7.194e-09 | -18.75 | GSE27786_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NKCELL_DN | 187 | 58 | 17758 | 2588 |
GSDMD,ANXA3,FRMD4A,LRP4,SDC4,SOD2,CUL1,C6orf106,HMGN3,FBXO6,DHRS3,PRKACA,SNX9,TMCC3,RB1,SNX13,ATP6V0B,TNS3,CCNA2,RPL39,PRC1,BRI3,TMBIM6,KLF9,ALPK1,FAR1,HSPA2,C9orf72,ALDH2,LONRF3,PLSCR1,PQLC3,CITED4,GUSB,MPP1,SPATA13,VAMP3,KIF13A,ZBTB7B,RNPEP,RNF19B,FZD7,NFIX,TNS4,TRAM2,SLC6A6,PTPRJ,HPSE,RBM47,TMEM30A,AXL,CDCA5,CTNND1,NFKBIZ,GEM,RTN3,CSRP2,NXT2 |
| 7.312e-09 | -18.73 | anion binding | molecular function | GO:0043168 | 2626 | 488 | 16491 | 2452 |
DOC2A,ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,SYTL4,CAMK1D,SEPT4,OAT,SNX9,KIF26A,DAPK2,PAK6,WEE1,HELZ2,TGFBR3,CTGF,UBE2T,DNAH6,ALDH1A3,SLC46A1,ATP13A3,PIK3CA,AOX1,DNM2,TUBG1,SNX16,CRY2,PIK3CD,ACOX2,PACSIN1,TIAM1,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,AURKB,TP53I3,POR,RAB2B,ARF4,ULK2,PGF,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,DHTKD1,MAPK13,RNASEL,ITPKA,ARF6,ANXA11,DDX58,RECQL,CDK17,ALDH6A1,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,SLC1A3,APBA1,FAM21C,MERTK,PDXDC1,BMP2K,C9orf69,RAC2,WDFY1,CYR61,SNX18,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,CNGA1,PIKFYVE,MAPK7,MAST4,DGKG,SYTL3,PHKG2,TTLL1,MCCC2,PRODH,KIF20A,ADCK3,MAPKAPK3,AMER1,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,PCTP,SPTLC2,GNA11,RHOB,STX3,PDE11A,STK17A,DHX32,DGKH,PTPRF,PRKAG2,CSNK1G1,DCK,ITPR1,ARAP1,AURKA,DYSF,STK39,CDK18,MAP3K5,IFIH1,TRPC3,NRBP1,RPS6KA3,TMEM173,XDH,EGLN1,EHD1,DMPK,PLA2G4A,KIF3C,MTM1,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,IQGAP1,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,AIFM2,PRKACA,FLT3,DDR1,MOCS1,ZFYVE9,NOV,APLP2,TRANK1,RALB,FICD,DAB2IP,PDE4D,ACSL4,EPHB4,ARL4D,RAB27B,SNX10,MYO5B,MX1,SNX8,RIPK2,AGPS,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ITPR3,SNX12,ATP10D,NIN,EPHA10,FYN,JAK1,ACAD10,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,PRKAR1A,GALK1,PCOLCE,TAOK2,HSP90B1,GCAT,ATP9A,ARL4C,PLD2,PKN1,DNAH3,IFT27,RND1,SGPL1,DIRAS3,IRAK1,CTSC,GPC3,MCF2L,FAM20B,SGK3,ATP8B1,PLEKHF1,ECI2,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,TTPA,MSH6,SMC4,HCN3,ACBD5,OPLAH,PCCB,ARAP2,CASK,SHMT1,RAPGEF2,GRIN1,UBE2A,AK4,PIM3,YES1,KIF11,CPTP,CRISPLD2,TXK,LDLRAP1,ACADSB,PLOD2,FGFR2,ACVRL1,SYT7,DBI,PLA2G15,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,WDR45B,ACOT7,MELK,ESYT2,TNK1,NMRK1,AGRN,ST13,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,ITPR2,KIF2C,ABCD4,ZFYVE16,RAB15,RPS6KA2,CDKL5,ARL1,PAPSS1,PSMC2,PASK,ABCA2,TRPC1,KIF22,RAB20,RP2,MYH14,DDX59,RASGRP1,STK35,PLK1,NLRP4,ATL1,MARK1,MCTP1,ACBD3,CCBL2,ARFRP1,ROR1,ESYT1,CDK1,ADRBK2,STK17B,VCP,RHEB,DPYSL3,SEC14L2,MDK,PI4K2B,WIPI1,P4HA2,IARS2,PIK3C2B,NRGN,PXDC1,TC2N,PSMC1,RRAGD,PRKAA2,RUNX2,ARAP3,LMTK3,SERPINE2,PEX6,BVES,ABCG2,RACGAP1,RAB6A,TEC,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ACAD8,GAD1,CCDC88A,SNX7,ABCC1,CYP26B1,TESK1,PDE5A,STRADB,EIF2AK1,PDK3,NUBP1,PDIK1L,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,COL13A1,PRPS2,P4HA3,RAB31,NLRC5,RHOBTB2,ALPK3,LTBP2,PLD1,KIF12,JAK3,CTBP1,SNX30,P3H2,ABCG4,DGKA,TP53,ERBB2,P2RX7,MRAS,CYP26A1,SYTL2,CDK14,KIF14,FABP6,SRR,PLK4,GOT1,OAS3,EGLN3,SCYL3,HSPA2,CTH,SEPHS1,MAP3K3,SIRT1,SOAT1,CLCN3,RFK,AKT1,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,IDE,ATP1A1,STK38,PTK7,MAOA,XRCC3,ANXA9,SYT13,RPL22,AIFM3,ABCA1,ANXA3,PINK1,DYRK3,PACSIN2,TOR4A,SHPRH,CIT,GNE,MCTP2,GNAL,ERCC6L,SELL,TGFBR1,CRABP2,NRP2,KIF5B,TOP2A,SNX13,ADRBK1,CDK16,BMP7,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,HMGCL,ABCD1,HSPA13,SYK,CAMK2G,ATP2B1,MYO5A,P2RX4,RAB3B,RHOA,GCLC,OGDHL,NADK2,RUNX3,SPAG1,DGKE,DDX23,DDAH1,MARC1,SWAP70,RND3,RAP2C,UBE2D2,ACADM,GEM,PLOD3,UBE2C,PTGES,L1CAM,HIPK3,ABCG1 |
| 7.657e-09 | -18.69 | CDK1 (cyclin-dependent kinase 1) | protein interactions | 983 | 234 | 72 | 16036 | 2547 |
REPS2,DLGAP5,FOXM1,PTTG1,TP53,CCNB1,BARD1,PCBP1,TP73,CCND1,PAK6,WEE1,APLP2,PCNA,NUP210,CCNA2,DNM2,CDKN1B,PPP1CA,MYT1,HSPA2,CKS2,SIRT1,MBP,PBK,CDC20,CDCA2,PKMYT1,CCNF,CDC25C,CDK1,VCP,FYN,TLE1,MLKL,HSPB1,RAP1GAP,LZTS1,RUNX2,CDK17,CDKN1C,NES,RACGAP1,FBXO6,LMNA,TOP2A,RB1,CALD1,PRC1,CKS1B,BUB1,ERCC2,EEF1D,RGCC,UBE2A,KIF20B,KIF11,EGFR,DCTN6,TSC1,CD8A,H1F0,ITPR1,CDCA5,RYK,E2F1,HMGA1,NDE1,CCNB2,JAK3,ESPL1,USP16 |
| 7.938e-09 | -18.65 | morphogenesis of an epithelium | biological process | GO:0002009 | 425 | 108 | 16441 | 2455 |
ACVR1,GRHL2,LGR4,ST14,EPHA4,RET,GATA3,MPP5,PLXNA1,PRKACA,DDR1,STIL,SETDB2,CTNNB1,NPNT,LMO4,ALDH1A3,SMO,DLG1,TWIST1,TACSTD2,PPP1CA,DLG3,ETV4,DVL2,EZR,TFAP2C,DAG1,LCP1,EDNRA,IRX3,SOCS3,ARHGAP35,AREG,SHROOM3,PTK7,PLXND1,COBL,CTHRC1,NKX3-1,TMTC3,CCM2,SDC4,SOX9,RAB23,CTSZ,JAG2,NCKAP1,HOXB2,SIX4,FZD6,GBX2,BMP2,CTNNBIP1,VASP,PDCD10,CA2,IGF1R,CYR61,FLRT3,MEGF8,GPC3,FRAS1,BMP7,BAX,TFAP2A,MAP3K7,WNT3A,NTN1,SLC12A2,SPRY2,EPB41L5,HES1,TGIF1,ADAM17,RHOA,FMN1,SALL4,DCHS1,PRICKLE1,SCRIB,KIF20B,NPHP3,ILK,EGFR,BCL10,ARHGAP24,TSC1,NCOA3,FAT4,ACVRL1,HTT,FGFR2,CSF1,TBX18,CTSV,SPINT2,SERPINB5,PKD2,HOXB13,SOX8,OSR1,FZD5,PLOD3,SEMA3A,RARG,FOXA1,ADAMTS16 |
| 8.206e-09 | -18.62 | endoplasmic reticulum | cellular component | GO:0005783 | 1604 | 315 | 17570 | 2579 |
IL15RA,PNPLA2,ATP8A1,DNAJC3,TAP1,FBXO2,VASH1,PLA2G16,PJA2,CYP1A1,STIM1,OSBPL3,CYP2S1,RDH14,MARCH2,ERAP2,BNIP3L,TMEM98,KDELR3,ICMT,MCFD2,CYP4F3,POR,RAB2B,COL12A1,SGPP1,KDSR,AREG,SARAF,TMEM8B,RTN3,SCN5A,SEC61G,CYP2J2,HLA-E,NOTCH2,MESDC2,CALR,NECAB3,FLRT3,SORL1,STT3B,MYDGF,MOXD1,TMED2,EEF1D,EPHX1,FAM69A,PIGC,FADS2,UFD1L,PQLC3,LPGAT1,ERO1A,PIP4K2C,CALCRL,NPC2,ATP8B3,MEST,SPTLC2,CYB5A,HTT,FAAH,APMAP,ZDHHC20,ITPR1,DGAT2,SAMD8,ALG2,MAP3K5,TMEM173,XDH,DMPK,PLA2G4A,CERCAM,CAST,APOO,MGST2,FLT3,CYP39A1,KTN1,EPM2A,CDS1,RCN1,XYLT2,ACSL4,OSBPL7,SULT2B1,SNX10,SEMA3B,MX1,SEC23A,SEC61B,ERMP1,COL6A2,TMEM43,SYNE2,CLSTN1,KIF1C,PKMYT1,RAB38,DNAJB14,B3GALNT2,ITPR3,TRIQK,ATP10D,GABARAPL1,ZMPSTE24,DDOST,WFS1,SLC9A6,PNPLA6,SLC27A1,NR3C2,MAMDC2,HSP90B1,MAN1A2,BACE1,TRAF2,PDIA3,CTSZ,PLD2,FBXO6,NUCB2,HLA-A,PDIA4,SGPL1,CAPN2,ANK1,RNF128,CTSC,ARSG,ALG13,CST3,BAX,ATP8B1,TMBIM6,CNPY3,TMX1,CRTAP,PDGFC,PIK3R1,EIF5A2,ELOVL3,GRIN1,FURIN,FOS,ARSK,NUCB1,PROM1,PLOD2,DBI,ERAP1,GPER1,ARSB,ESYT2,RGMA,UNC93B1,FAF2,EPHA4,DNAJB11,ITPR2,CDIPT,PDGFB,ERP29,PIGL,ABCD4,NUP210,METTL7A,P4HB,LMAN2L,PHTF1,DLG1,SCARA3,TECR,TRAM1,RASGRP1,CYP1B1,CERS2,ATL1,KCNIP3,SYNE3,STAU2,NFE2L1,ERP44,KLK6,ESYT1,PTGFRN,VCP,RHEB,AGPAT2,MAP2,P4HA2,DOLPP1,PIK3C2B,TTC9,PIEZO1,POMT1,FAM213B,HLA-F,FXYD3,ELOVL7,DHRS3,ADAMTSL4,PGAP1,CES2,COL6A1,SUCO,SELK,HLA-C,WNT3A,NCEH1,FAR2,ALDH3A2,CKAP4,CCDC88A,KDELR1,CYP26B1,EMC2,ZDHHC3,EGFR,MOSPD3,FA2H,COL13A1,PLPP3,TMEM30A,MFSD2A,P4HA3,ZDHHC7,CTSA,PLD1,COL16A1,APOL2,DRD1,P3H2,XYLT1,PDIA5,TP53,COL18A1,LPIN3,EXT2,BCAP31,CYP26A1,PDGFA,SRPX,CYP4F11,ZDHHC12,REEP1,ZDHHC23,RPN2,TMEM64,NOTCH3,LMAN1,MINPP1,PDIA6,CHP1,SULF2,SOAT1,EVA1A,ERLEC1,C3orf52,ACO1,TMTC2,CASP4,DNAJC10,TAPBP,PTGS2,ATP1A1,CANT1,CYP2U1,AIFM3,REEP4,POMGNT2,KDELC2,FAM134B,COL9A3,CDS2,SORT1,CPEB4,SCD5,JKAMP,NKRF,COL4A5,CRABP2,DSE,LBR,DNAJB9,ZDHHC21,ADORA1,RRBP1,UBE2J1,SLC35B4,ZDHHC13,SGK1,HSPA13,CAMK2G,MYO5A,MLEC,RHOA,PLAUR,AMFR,COL7A1,CARD19,TXNDC11,MAPK8IP1,PRDX4,HLA-B,TMEM50B,SERPINA1,PGRMC1,PKD2,SPCS3,PLOD3,PTGES,ABCG1 |
| 8.325e-09 | -18.60 | regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0000079 | 87 | 35 | 16441 | 2455 |
CCNE2,CCNC,CASP3,HERC5,PSMD10,CCNL1,PDGFB,STIL,CCND1,TFAP4,CDKN2C,DIRAS3,CCNA2,PTEN,FBXO7,CKS1B,CDKN1B,PIM1,HEXIM2,CDKN2D,HSPA2,CKS2,PLK1,PSRC1,ADAM17,AKT1,RGCC,PKMYT1,CDC25C,CDK5R1,EGFR,CDK5RAP1,CCNB3,PKD2,UBE2C |
| 8.908e-09 | -18.54 | cellular response to chemical stimulus | biological process | GO:0070887 | 2460 | 462 | 16441 | 2455 |
ACVR1,TRIM24,SSH1,ADD1,IL15RA,TRIM5,DNAJC3,RET,CUL1,NRG2,GATA3,PSME1,IL18,CCNB1,PICK1,CALM2,ZYX,CYP1A1,PSMD1,TGFBR3,CTGF,ELMO2,CYP2S1,IL31RA,KLF3,FOSB,PIK3CA,DNM2,IRF2,PPP1CA,PIK3CD,TIAM1,IL10RB,TIPARP,CASP9,KDELR3,AGO4,PRKAR2B,CYP4F3,POR,ABR,ENPP1,PLCG1,TBX1,NOD2,HDAC1,EIF4EBP2,MAPK13,RNASEL,HSPB1,GAB1,FGD1,SCN5A,KLF2,SEC61G,CYP2J2,HLA-E,SOX9,PRKAA1,TNFRSF19,LMNA,TFAP4,CALR,MEGF8,VASN,FLRT3,DAPK1,TNFRSF12A,CD70,MYDGF,NCAM1,MAPK7,NUP85,EPHX1,SOCS5,PAQR7,EPB41L5,GFPT1,UFD1L,PRODH,MAPKAPK3,STAT4,CALM1,ANO6,ERO1A,SHARPIN,CALCRL,ELK1,KDM3A,PSMA4,RHOB,RASA1,FAS,IL1R1,NCOA3,FNTA,PRKAG2,ITPR1,DGAT2,OSMR,NR4A2,MAP3K5,NUP58,RPS6KA3,TMEM173,EGLN1,EHD1,IRF1,PLA2G4A,SPRED1,SLC2A4,NQO1,PAPSS2,THRA,RPS6KA1,IQGAP1,NDRG1,WDTC1,IL13RA1,MGST2,BCL2L1,EGR3,PRKACA,FLT3,CYP39A1,GNB2,ZFYVE9,CCND1,NOV,ACAP2,CDH1,SP100,RALB,CDKN1B,DAB2IP,PDE4D,IFIT1,OSBPL7,RASGEF1A,SULT2B1,NR2C1,MX1,DOCK4,SEC61B,RIPK2,FZD4,DMTN,SYP,PRKCQ,SLC11A2,CBL,ITPR3,FZD7,IRS2,ALDH3B1,FYN,JAK1,CDK19,NGFRAP1,WFS1,AXL,WWTR1,STAT1,PPP1CB,SLC27A1,NRG1,NR3C2,ARNT,MAPK12,PRKAR1A,ARHGEF3,PLSCR4,NKX3-1,TNRC6C,HSP90B1,TRAF2,FLOT1,HERC5,ETS1,GSTP1,FGF19,ICAM1,HLA-A,CAPN2,CXCL16,PDCD10,IRAK1,PTEN,MCF2L,CST3,FDXR,FUT8,CD9,BAX,IGFBP2,MAPK11,ERBB3,CITED2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,HCN3,OPLAH,RASGRF1,TGIF1,PDGFC,ALDH2,SHMT1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,FOS,GPLD1,TIMP3,PLOD2,FGFR2,RAB11FIP2,ACVRL1,NR1D2,PRDX3,SLC35B3,NR4A3,OSER1,GRIN2D,GPER1,CMPK2,NUP37,OSR1,CD81,USF2,CPEB2,MELK,RGMA,PHC1,CCNC,CASP3,UGT8,EPAS1,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,TRIM68,SPTB,ZFYVE16,CPNE2,NUP210,RPS6KA2,CTNNB1,NPNT,SHC3,P4HB,ZCCHC12,IL6ST,PSMC2,PAPSS1,AKR1B1,TNFRSF18,IL1RAP,RASGRP1,SP5,CYP1B1,THRB,SOD1,TRIM8,USP18,NFE2L1,EZR,PRKRA,VCP,RHEB,DPYSL3,MAP2,WIPI1,MADD,CAB39,ADIPOR1,KPNA2,PSMC1,PPP2R5D,NR2C2,PCSK5,RRAGD,PRKAA2,RUNX2,LGALS3,HLA-F,RASA2,ETV5,PSMD7,ATP6V1E2,CALM3,PHLPP1,DUSP5,IL18R1,CORO1B,BMP2,SPP1,RB1,CES2,IGF1R,PAK2,COL6A1,PRKCI,AHCY,PIM1,C10orf54,HLA-C,WNT3A,PSMA5,HP1BP3,CYP26B1,RGMB,OXR1,STRADB,TCF7,PDK3,IFIT3,EGFR,RASGRP2,GNAS,FECH,MAPKAPK2,TSC1,INSR,PHLPP2,CSF1,NFKBIA,SH3BP4,RAB31,YOD1,LTBP2,JAK3,COL16A1,RARG,IFI6,DRD1,GAS2L1,SLC25A24,SORBS1,UGP2,IL15,SLC2A8,PSME2,PDIA5,TP53,SOD2,ERBB2,P2RX7,IL27RA,RASGRP3,ARHGEF16,CYP26A1,PDGFA,ATP6V0B,CYP4F11,SMO,GOT1,TWIST1,OAS3,NFKB2,EGLN3,PDIA6,CTDSP2,FRS3,CTH,SIRT1,PPIF,TIMP2,BAG4,TCEB2,AKT1,ERBB2IP,DUSP4,CD40,CASP4,SOCS3,ATP13A2,DUOX1,PTGS2,IDE,ATP1A1,RBL1,PSMD3,STAT6,PTK7,MAOA,SPTBN5,IRF7,CYP2U1,ARHGAP4,ABCA1,LIFR,GCLM,PINK1,SORT1,CPEB4,TAB3,ARHGEF11,ARHGEF7,CTSB,SERPINB9,LRP4,GABRG2,PSMD10,TGFBR1,GDF15,AIP,IL22RA1,DNAJB9,NRP2,HDAC9,IL17RB,ADRBK1,BMP7,TFAP2A,IL17RA,TRIM21,KLF9,IQGAP3,SYK,CAMK2G,MYO5A,DUSP1,P2RX4,ADAM17,RHOA,PSMB4,WNT10B,NR3C1,IFITM3,AMFR,GCLC,NR4A1,LITAF,PPARA,RGCC,BCAR1,BBS2,LEPR,CTSL,HLA-B,TWSG1,SCG2,DHRS2,NAT1,FGF18,E2F1,UBE2D2,PKD2,ATP6V1C1,PLOD3,TBC1D4,AHR,ARHGEF9,ARHGEF4,NGEF |
| 9.257e-09 | -18.50 | testis-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-non_seminoma | 500 | 120 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,RPS6KA1,EPHA4,RET,TP53,ERBB2,TESK2,GRK6,CAMK1D,PRKACA,FLT3,DDR1,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CDKL5,PLK4,EPHB4,SCYL3,STK35,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,PBK,PRKCQ,ROR1,PKMYT1,AURKB,MAP3K6,ADRBK2,STK17B,ULK2,EPHA10,FYN,JAK1,CDK19,PLK2,PTK7,STK38,AXL,LIMK1,MYLK,KIAA1804,MAP3K11,MAPK13,RNASEL,MLKL,FAM134B,MAPK12,PRKAA2,PINK1,DYRK3,TAOK2,CDK17,PRKAA1,TGFBR1,ADCK5,PKN1,TRIB2,MERTK,BMP2K,IGF1R,IRAK1,ADRBK1,CDK16,NEK2,DAPK1,SGK3,PRKCI,MAP3K9,ADCK2,PRKG1,FNIP1,SGK1,MAPK11,BUB1,ALPK1,PIM1,ERBB3,MAPK7,MAP3K7,SYK,PHKG2,CAMK2G,CASK,ADCK3,TESK1,DCHS1,STRADB,EIF2AK1,YES1,PDK3,PDIK1L,EGFR,BSDC1,TXK,STK17A,MAPKAPK2,INSR,ACVRL1,FGFR2,ALPK3,AURKA,CDK18,MAP3K5,JAK3,HIPK3,NRBP1,RPS6KA3,MELK,DMPK,GOLGB1 |
| 9.744e-09 | -18.45 | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN | 193 | 59 | 17758 | 2588 |
ARHGAP11A,CASP3,SPC25,FRMD4A,SERPINE2,ST14,CKAP2,UBASH3B,NDRG1,SLC25A13,ETV5,HMGN3,PHLPP1,FAM81A,SNX9,CHST2,CD109,CCNA2,RNF128,TACC2,TOX2,RANBP1,NEK2,PLK4,KIF22,BUB1,C12orf75,GCNT1,SYPL1,GCA,PCGF5,MMD,IFITM3,FIGNL1,LAP3,CORO2A,STAU2,LPGAT1,LITAF,CBX6,DUSP4,AKR1E2,C15orf39,PCTP,CD83,OPTN,MAP2,PLOD2,TIMM8A,INPP4B,KPNA2,SGOL1,NCAPG2,CCNB2,CD81,HOOK1,NRGN,MELK,STARD3NL |
| 9.988e-09 | -18.42 | lung-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-bronchioloalveolar_adenocarcinoma | 797 | 174 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,PPFIBP2,CAMK1D,CCNB1,TMC1,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,STK35,PLK1,NEK4,MARK1,ACVR1C,FOPNL,PBK,ROR1,AURKB,RNF19B,ADRBK2,STK17B,ULK2,TRIM9,PLK2,LIMK1,MYLK,MAP3K11,DHTKD1,HDAC1,MAPK13,SERPINI1,RNASEL,APBA2,PRKAA2,CDK17,LRRFIP2,PRKAA1,C6orf106,ADCK5,NCKAP1,NOTCH2,MERTK,BMP2K,RB1,IGF1R,NEK2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,USP38,OSTF1,ALPK1,PIM1,MAPK7,KCTD3,PHKG2,MPHOSPH9,RIMS2,ADCK3,TESK1,PYGL,STRADB,EIF2AK1,PDK3,PDIK1L,EGFR,STK17A,MAPKAPK2,INSR,PRPS2,ALPK3,OSMR,AURKA,CDK18,NDE1,MAP3K5,DRP2,JAK3,NRBP1,RPS6KA3,DMPK,NF2,RPS6KA1,TP53,P2RX7,TESK2,ERBB2,GRK6,FAM91A1,PRKACA,FLT3,DDR1,TMPRSS4,CYP26A1,CDK14,C11orf84,ZNF687,WDR44,PLK4,EPHB4,PHKA2,ZNF365,SCYL3,SUSD3,MAP3K3,RIPK2,AKT1,PRKCQ,PKMYT1,ATP10D,MAP3K6,EPHA10,FYN,JAK1,CDK19,PTK7,AXL,STK38,INPP4B,KIAA1804,STAT1,MLKL,MAPK12,PINK1,DYRK3,TAOK2,TRAPPC10,SDC4,TGFBR1,COL4A5,PKN1,TRIB2,NFAT5,PPP2R3A,KIF5B,E2F7,ADRBK1,IRAK1,PTEN,CDK16,SGK3,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,PHF20L1,CASK,PIK3R1,RUNX3,YES1,TXK,GPLD1,DDAH1,CASP7,FGFR2,ACVRL1,ARRB1,GRIN2D,HIPK3,MELK,USP16,DIS3L |
| 9.988e-09 | -18.42 | bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | bronchioloalveolar_adenocarcinoma | 797 | 174 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,PPFIBP2,CAMK1D,CCNB1,TMC1,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,STK35,PLK1,NEK4,MARK1,ACVR1C,FOPNL,PBK,ROR1,AURKB,RNF19B,ADRBK2,STK17B,ULK2,TRIM9,PLK2,LIMK1,MYLK,MAP3K11,DHTKD1,HDAC1,MAPK13,SERPINI1,RNASEL,APBA2,PRKAA2,CDK17,LRRFIP2,PRKAA1,C6orf106,ADCK5,NCKAP1,NOTCH2,MERTK,BMP2K,RB1,IGF1R,NEK2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,USP38,OSTF1,ALPK1,PIM1,MAPK7,KCTD3,PHKG2,MPHOSPH9,RIMS2,ADCK3,TESK1,PYGL,STRADB,EIF2AK1,PDK3,PDIK1L,EGFR,STK17A,MAPKAPK2,INSR,PRPS2,ALPK3,OSMR,AURKA,CDK18,NDE1,MAP3K5,DRP2,JAK3,NRBP1,RPS6KA3,DMPK,NF2,RPS6KA1,TP53,P2RX7,TESK2,ERBB2,GRK6,FAM91A1,PRKACA,FLT3,DDR1,TMPRSS4,CYP26A1,CDK14,C11orf84,ZNF687,WDR44,PLK4,EPHB4,PHKA2,ZNF365,SCYL3,SUSD3,MAP3K3,RIPK2,AKT1,PRKCQ,PKMYT1,ATP10D,MAP3K6,EPHA10,FYN,JAK1,CDK19,PTK7,AXL,STK38,INPP4B,KIAA1804,STAT1,MLKL,MAPK12,PINK1,DYRK3,TAOK2,TRAPPC10,SDC4,TGFBR1,COL4A5,PKN1,TRIB2,NFAT5,PPP2R3A,KIF5B,E2F7,ADRBK1,IRAK1,PTEN,CDK16,SGK3,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,PHF20L1,CASK,PIK3R1,RUNX3,YES1,TXK,GPLD1,DDAH1,CASP7,FGFR2,ACVRL1,ARRB1,GRIN2D,HIPK3,MELK,USP16,DIS3L |
| 1.003e-08 | -18.42 | clear_cell_carcinoma | COSMIC cancer mutations | clear_cell_carcinoma | 691 | 155 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,GATA3,NDRG2,CAMK1D,DPP8,ABCD4,PAK6,DAPK2,WEE1,CYP1A1,RPS6KA2,CTNNB1,CDKL5,PAPSS1,PIK3CA,IL1RAP,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,ROR1,AURKB,IDH1,ADRBK2,STK17B,ULK2,PLK2,CELF5,LIMK1,MYLK,MAP3K11,MAPK13,RNASEL,GRN,PRKAA2,BMF,CDK17,PRKAA1,ADCK5,MERTK,BMP2K,RB1,IGF1R,NEK2,MSH2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,SLC12A2,KCTD3,PHKG2,PLEKHA6,ADCK3,TESK1,STRADB,PLS1,EIF2AK1,KIAA1109,PDK3,PDIK1L,EGFR,STK17A,GNAS,MAPKAPK2,INSR,PHLPP2,SLC4A3,PIAS2,ALPK3,AURKA,CDK18,MAP3K5,ARPC2,JAK3,NRBP1,RPS6KA3,DMPK,RPS6KA1,TP53,TESK2,ERBB2,GRK6,PRKACA,DDR1,FLT3,CDK14,UHRF1BP1L,CDH1,PLK4,EPHB4,SCYL3,MYO5B,MAP3K3,RIPK2,AKT1,UTRN,PRKCQ,PKMYT1,TRIM7,MAP3K6,SOCS3,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,LIFR,MAPK12,PINK1,TAOK2,HSP90B1,DYRK3,TGFBR1,PKN1,TRIB2,ADRBK1,OXCT1,IRAK1,PTEN,CDK16,TFAP2A,SGK3,SGK1,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,MSH6,PGM1,CASK,PIK3R1,YES1,TXK,FAT4,FGFR2,ACVRL1,HIPK3,MELK |
| 1.005e-08 | -18.42 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | 245 | 70 | 17758 | 2588 |
LTBP1,UGP2,ADD1,HEBP1,NDRG1,TMX4,MORC4,COL18A1,IL27RA,MAP1LC3B,CARD10,APOBEC3B,KCNS3,EPB41L4B,PTPRE,S100A13,SCN3A,COL6A2,PTPRU,PBK,SEPT6,PRKAR2B,LOXL2,ADRBK2,IRS2,PGF,TRAM2,CARHSP1,JAK1,MAFF,PCSK5,IGFBP6,SERPINE2,ZNF395,SDC4,ARL4C,NTAN1,NRP2,M6PR,TNS3,ANK1,TIMP1,CTSC,GATA2,CYR61,GPC3,CD9,FXYD5,SGK1,OSTF1,GAD1,DUSP1,FAM69A,TGIF1,PDGFC,HES1,ELK3,PLSCR1,MMD,NR3C1,RHOB,DDAH1,SERTAD2,FAM3C,DTX4,CLMN,ARRB1,CTSA,MAP3K5,CYBRD1 |
| 1.007e-08 | -18.41 | MODULE_1 | MSigDB lists | MODULE_1 | 359 | 93 | 17758 | 2588 |
MYL9,LTBP1,BCAM,HSPG2,S100A11,IQGAP1,GMPR,PDGFRL,EGR3,SDC1,EMP2,CHPF,IER3,CCND1,ZYX,ST5,TGFBR3,SRPX,LMO4,PSMC2,MITF,FOSB,AOX1,BCL6,RGS5,IFIT1,NOTCH3,LGMN,TIPARP,LOXL1,CPE,SMARCA2,SGCE,CD55,COL6A2,TIMP2,LHFPL2,OPTN,EDNRA,DPYSL3,MDK,TRAM2,PDLIM3,WFS1,MYLK,WWTR1,PLXND1,MAFF,PCOLCE,CDKN1C,IGFBP6,ITGA6,EPS8,AKAP17A,TRIB2,SEPP1,DHRS3,FBLN1,TSPAN7,LMNA,CYR61,CALD1,GPC3,COL6A1,SGK1,ALDH7A1,IGFBP2,PIM1,NCAM1,CITED2,EPHX1,QSOX1,HES1,PRSS23,PLSCR1,NR4A1,FHL2,EMP3,SRSF5,FOS,RHOB,FUCA1,IL1R1,PVRL2,DHRS2,ITGA7,ITPR1,RAB31,TCEAL4,NR4A2,LTBP2,GEM,COL16A1 |
| 1.014e-08 | -18.41 | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | 135 | 46 | 17758 | 2588 |
SLC35D2,NQO1,ESRP1,ITGA6,ETNK1,PDIA5,PDIA3,F11R,SH2D4A,SYTL2,COX7A2,PDIA4,MESDC2,MECOM,ASPHD2,EPCAM,CA2,RNF128,LLGL2,TMEM62,DOK4,ATP8B1,ERBB3,EPHB4,CPD,ACBD5,GFPT1,CXXC5,CASK,KIAA1841,C3orf52,PLS1,ATP1B1,GALNT7,GRTP1,GALNT3,SFXN1,DDAH1,KCNK1,VSIG10,KLF5,STK39,SH3BGRL2,MAL2,SYT13,FZD5 |
| 1.015e-08 | -18.41 | neuron projection development | biological process | GO:0031175 | 866 | 190 | 16441 | 2455 |
MYL9,EMX1,UGT8,AGRN,CUL4B,EPHA4,ARFGEF1,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,WEE1,PSMD1,RPS6KA2,SHC3,DPYSL2,PSMC2,DLG1,DNM2,TRPC1,NTN4,CTTN,MYH14,PACSIN1,TIAM1,BTBD3,RASGRP1,ATL1,CELSR2,RNF165,EZR,ULK2,ARF4,DPYSL3,PLCG1,AREG,MAP2,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,PSMD7,CALM3,CNTNAP2,DUSP5,RB1,RAC2,VASP,IGF1R,FRY,LRRN2,MEGF8,FLRT3,PAK2,COL6A1,PRKG1,CACNA1D,NCAM1,WNT3A,NTN1,PSMA5,DPYSL5,RGMB,CALM1,KIF20B,EPHA1,ILK,DPYSL4,NFIB,PSMA4,RANBP9,STX3,RHOB,EGFR,RASA1,CDK5R1,PTPRF,SEMA4D,MATN2,CLMN,AURKA,PITPNA,NR4A2,EFNA1,B4GAT1,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,KLF7,EHD1,SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,RASGRP3,MICALL2,PDGFA,ARTN,CDH1,DACT1,FRYL,DAB2IP,ACSL4,EPHB4,RASGEF1A,DLG3,ETV4,SEMA3B,FRS3,CAMSAP3,COL6A2,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,EPHA10,IRS2,FYN,RTN4RL1,JAK1,SLC9A6,PSMD3,SPTBN5,NRG1,EFNA5,PLXND1,LIFR,COBL,COL9A3,FARP1,ARHGEF11,ARHGEF7,CIT,LRP4,FLOT1,PSMD10,COL4A5,PLPPR4,EFNB1,FGF19,ITGA2B,NRP2,RND1,GBX2,NEO1,KIF5B,ANK1,IGSF9,PTEN,CDK16,BMP7,SGK1,ERBB3,S100A6,CAMK2G,FARP2,RASGRF1,RHOA,ARHGEF28,B3GNT2,PSMB4,FMN1,RAPGEF2,GRIN1,STMN3,YES1,ABLIM2,MAP1B,CNTNAP1,FGFR2,FGF18,RYK,PGRMC1,NR4A3,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 1.027e-08 | -18.39 | LIU_VMYB_TARGETS_UP | MSigDB lists | LIU_VMYB_TARGETS_UP | 118 | 42 | 17758 | 2588 |
FAM134A,ARL4C,ABCG2,GMCL1,PHLPP1,NUCB2,CA8,PSIP1,H1FX,SAC3D1,IL17RB,RPS6KA2,GNB5,TACC2,DPYSL2,LHX6,KCNS3,ALDH7A1,EPB41L4B,HSPA2,MPHOSPH9,SNX7,NAGPA,ARAP2,MMD,PLSCR1,CTNNAL1,HSPA12A,BNIP3L,EMP3,PRKAR2B,ALCAM,FZD7,ULK2,STK17A,MAPKAPK2,FYN,RBM47,NMI,KLF11,SLC31A2,NXT2 |
| 1.035e-08 | -18.39 | negative regulation of cell death | biological process | GO:0060548 | 894 | 195 | 16441 | 2455 |
CASP3,TXN,ACVR1,GRIK2,TSC22D3,FAM129B,DNAJC3,XIAP,GATA3,PSME1,CAMK1D,BARD1,TP73,EPCAM,PSMD1,CTNNB1,CTGF,IL6ST,PSMC2,IL31RA,MITF,PIK3CA,TNFRSF18,CTTN,ARNT2,SLC39A10,ANKRD9,PLK1,SOD1,ITCH,BNIP3L,AURKB,SLC25A5,CDK1,POR,ARF4,OPTN,MDK,SLC25A4,PLK2,TBX1,MADD,NOD2,HDAC1,UNC5B,HSPB1,PSMC1,PRKAA2,BMF,LGALS3,ITGA6,SOX9,PRKAA1,PSMD7,SLC25A27,NOTCH2,MERTK,LMNA,MECOM,TIMP1,IGF1R,CYR61,PAK2,MSH2,DAPK1,PRKCI,FNIP1,SORL1,MYDGF,PIM1,MAPK7,PSMA5,OXR1,FHL2,STRADB,ILK,IFIT3,PSMA4,EGFR,G2E3,RASA1,FAS,SEMA4D,HTT,NFKBIA,AURKA,NR4A2,CABIN1,JAK3,RARG,IFI6,RPS6KA3,RPS6KA1,PSME2,CAST,TP53,SOD2,ERBB2,EGR3,BCL2L1,STIL,IER3,NOV,KIF14,PLCG2,BCL6,SMO,CDKN1B,TWIST1,APIP,LGMN,CDKN2D,F2R,TMBIM1,CTH,SIRT1,PPIF,BAG4,RIPK2,AKT1,FIGNL1,VPS4B,HTATIP2,PRKCQ,GLO1,CBL,SOCS3,IRS2,FYN,BHLHB9,AXL,WFS1,PSMD3,TLE1,CHMP4B,NRG1,IRF7,AREL1,LIFR,CBX4,ZC3HC1,FAM134B,GCLM,PINK1,HSP90B1,CPEB4,TRAF2,CTSB,SERPINB9,PSMD10,NES,TGFBR1,GSTP1,ICAM1,SIX4,PDCD10,ADORA1,IRAK1,PTEN,BMP7,CST3,TFAP2A,BAX,TMBIM6,KANK2,ERBB3,CITED2,FAIM,RAG1,MAP3K7,TTPA,SPRY2,DUSP1,RHOA,PSMB4,HMGN5,PLAUR,GCLC,PIK3R1,GRIN1,PPARA,PELI3,PIM3,MAPK8IP1,BCL10,FGFR2,SCG2,PRDX3,DHRS2,NR4A3,ARRB1,ITGAV,OSR1,SOX8,HIPK3 |
| 1.054e-08 | -18.37 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN | 198 | 60 | 17758 | 2588 |
TXN,DLGAP5,LGALS3,S100A11,GNPDA1,SEC61G,SERPINB9,PTTG1,EFHD2,RACGAP1,KIF2C,MNS1,IL18R1,REPS1,KCTD9,HLA-A,TOP2A,CDKN2C,RRBP1,PRC1,CKS1B,KIF22,MDFIC,AK3,F2R,SNX10,S100A13,S100A6,PQLC3,PLSCR1,S100A4,DSTN,CDC20,CRIP2,LITAF,CAPNS1,NUSAP1,GGH,PRRC1,DOCK5,RNPEP,KIF11,CDC25C,CDK1,CASP4,PRDX4,GALNT3,NUCB1,CARHSP1,IDE,CASP7,CDCA5,DBI,GEM,ARF6,SGOL1,CCNB2,CHPT1,E2F8,ACOT7 |
| 1.066e-08 | -18.36 | cell part | cellular component | GO:0044464 | 15692 | 2382 | 17570 | 2579 |
HECA,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,SPSB1,GRM5,LYPD5,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,LCP1,ABR,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,SEC61G,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,PPP6R1,MCCC2,REC8,PYM1,FHL2,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,PLIN5,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,C5orf30,MAPK4,MGST2,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,SEPT6,PTPN9,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,ZNF618,NFIX,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,ESRP1,DCAF7,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,CTSZ,ZNF219,HDGFRP2,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,KLC3,BAX,IGFBP2,MED22,ACBD5,PVRL4,TACC1,PIK3R1,DUSP23,MRS2,NUB1,PGBD1,RAB3IP,PIM3,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,WDR45B,SRSF9,ACOT7,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,INPP5E,BTG3,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,DZIP1L,TRIM9,PI4K2B,KCNMB4,HOXA9,ARRDC1,KLF11,RUNX2,LMTK3,PARP12,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,EMC2,STRADB,ZSCAN12,PDK3,PRX,CDK5R1,COL13A1,PHLPP2,KBTBD2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,RHPN2,PCBP1,BCAP31,IER3,KMT5C,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,CFAP36,ATP13A2,ZNF628,PTPRJ,IDE,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ARFGEF3,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,UBE2J1,IL17RA,ALDH7A1,CPLX1,TSPAN13,ATP2B1,GCNT1,DUSP1,NFE2L3,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,SSH1,HSPG2,LGR4,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,HELZ2,TYMP,ANKS6,OSBPL3,PALD1,FOSB,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,SH2D3C,BMP1,NFKBIZ,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,PPP4R1,MSH2,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,EPHA1,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,AGBL5,PIAS2,APPL2,SFMBT1,KLK7,SAMD8,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,PDE4D,OSBPL7,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,MSANTD4,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,PYGO1,PKMYT1,ASB13,CBL,B3GALNT2,TRIQK,FZD7,CEP162,ACAD10,NGFRAP1,TRIOBP,CBX7,MAMDC2,DEPDC1,IGFBP6,EPS8,HERC5,PLD2,FBXO6,SPDL1,FGF19,EFNB1,COX7A2,WWP2,SCML1,SLC25A36,E2F7,RNF128,GNB5,CD9,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,CPTP,DCTN6,ACADSB,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,ESPL1,DEF6,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,EPCAM,ZFYVE16,HSF2,CASC4,ARHGEF37,METTL7A,CDKL5,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,SUCO,PRKCI,BRAT1,C10orf54,GAD1,ETV7,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,STEAP1,RANBP9,SOX13,UAP1,SPAG7,RAB31,DCUN1D1,CTSA,TOB1,RARG,AFAP1,SNX30,NBPF1,LZTFL1,DYNLRB1,SORBS1,PAX6,PDIA5,COL18A1,IL27RA,MRAS,SAYSD1,PHLDA1,ZNF687,COX14,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CHP1,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ARHGEF7,TGFBR1,NTAN1,SBF1,XPR1,TMEM63A,KIF5B,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,DCAF6,RC3H2,SYBU,RGCC,LEPR,LEMD2,ARHGAP24,CTSL,CASP7,TRIM69,SPINT2,RAP2C,DTX4,UACA,ARRB1,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,CACNA2D2,SMARCAL1,NRG2,LYNX1,CNTROB,MORF4L2,SYTL4,BARD1,PHF1,DAPK2,ZYX,AP1M2,TGFBR3,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,GRID2IP,WDR11,DNM1L,ANKRD6,MYLK,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,ILK,DCP2,CYB5A,STK17A,DHX32,NAAA,NCOA3,MTFMT,SEMA4D,HTT,SETD3,TEX30,ITPR1,AURKA,GSKIP,ALG2,B4GAT1,MAL2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,NUF2,IL13RA1,KTN1,CDS1,CCND1,SCNN1A,RNF220,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,RNF169,SCN3A,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,TRABD2A,PDXK,RGS14,ARNT,TNRC6C,NKX3-1,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,DTX3L,CAPN2,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,DCAF10,PITX2,CCDC6,ATXN7L3,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,UNC93B1,TRIM2,AGRN,GNPDA1,EPHA4,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,UBASH3B,ASAH1,DOCK11,PGAP1,BMP2,GATA2,CMTR2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,KCNAB3,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,CYP26A1,C1orf116,CDK14,RAD23A,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TIMP2,TCEB2,S100A4,CDC20,DUOX1,RTN4RL1,ATP1A1,PSMD3,RPL22,AIFM3,ZNF701,COPG1,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,ADGRG1,RUSC2,GNE,SWI5,PSMD10,NKRF,SIRPA,SLC9A2,PPP2R3A,MTRNR2L1,CEP97,BUB1,HEXIM2,FAIM,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,CARD19,FXR2,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,TMEM50B,NAT1,ZNF214,NETO2,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,CFAP74,ACVR1,PPP4R4,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,RIC1,SESN3,CTGF,ZFP36,IL31RA,STEAP2,AOX1,TFG,RCAN3,XKR8,LAMP2,LOC81691,SNTB2,PBK,CASP9,TNS1,PIF1,GALNT7,SLC17A5,CCNF,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,TBX1,NKD1,DHTKD1,SARAF,EIF4EBP2,TMEM8B,TRAF5,LZTS1,DLAT,KLF2,MRPL44,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,MICB,AMER1,PIP4K2C,CYFIP2,KDM3A,RASA1,FAS,PRKAG2,CSNK1G1,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PLA2G4A,FRMPD3,ELK4,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,RNF182,EGR3,SNN,NUDT12,GNB2,SLC25A35,APLP2,DOK4,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,JAK1,CFAP45,STK26,KIAA1804,NRG1,RAB29,B4GALT3,ATMIN,OTUD5,NUDT6,ARHGEF3,ANKRD13D,SLC16A14,ARL4C,CDCA3,APOBEC3H,TEAD3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,PRC1,SGK3,ATP8B1,ERCC2,CNOT6L,CNPY3,PCCB,SHMT1,CASK,DENND1B,MPP1,TEF,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,SLC25A40,CSTF2,PGM2L1,ETAA1,SLC25A38,CPEB2,OCLN,CAMKK1,HEBP1,UBE2Z,TAF6L,CACNB4,DENND2D,TMC1,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,SUN3,RAB20,NFU1,MYH14,PTPRE,TRIM8,ASCL5,SYNE3,ROR1,TCN2,EDNRA,MDK,CXXC4,ZNF114,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,PIFO,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,HMG20B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,PLPP3,NFKBIA,CDCA5,RHOBTB2,ALPK3,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SLC25A48,SS18,ZDHHC12,FRYL,SMO,GOT1,STEAP3,RPN2,APIP,F2R,LOXL1,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,JKAMP,FRMD6,ARMC7,TRMT2B,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CFAP43,CKS1B,BRD7,RAB3B,CENPC,MBNL3,OGDHL,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,ZNF596,SNPH,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,ISOC2,LACTB2,SNX9,CARD10,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,WBP4,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,PRKAR2B,RNF19B,ARF4,GINS4,PLCG1,CARHSP1,ENPP1,ATP7B,CELF5,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,RABGGTA,MARCH8,TFAP4,FLII,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,FBXO7,RANBP1,PCYOX1,CADPS2,SLAIN2,FAM84B,MYDGF,ZMYM1,MYLIP,ULBP2,DGKG,PHKG2,PAQR7,HPS3,PQLC3,MAPKAPK3,SHARPIN,ERO1A,KIF20B,PSMA4,GNA11,SFXN5,IL1R1,FNTA,APMAP,S100A5,CLMN,STK39,CFAP20,CBX5,NUP58,RUSC1,DOCK9,TPRN,NQO1,LFNG,INPP5D,CD82,PTTG1,APOO,MVB12B,MOCS1,REPS1,APPBP2,RCN1,CDH1,SH3BP1,XYLT2,LRP11,RASGEF1A,DLG3,ETV4,SNX10,MX1,SEC61B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GABARAPL1,ALDH3B1,CCNB3,PNPLA6,ISOC1,MAPK12,TCAF1,MZT1,GCAT,TRAF2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,FAM20B,CST3,RAG1,PARP9,OPLAH,PLSCR1,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,PHC1,ILDR1,LMCD1,DNAJB11,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PSMC2,PAPSS1,PASK,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,PLEKHG6,HS6ST1,KLF12,AGPAT2,ZNF367,KPNA2,TC2N,MYL12B,RRAGD,PRSS8,HJURP,LGALS3,DNAJB2,SLC22A31,PDCL,SORBS3,ADCK5,HES2,RAB6A,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,FAM213A,RAD21,CTDSPL,TP53,P2RX7,BAHD1,EMP2,STIL,PRR7,SYTL2,TMSB15B,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,STK38,MMP17,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,LBR,AIP,VPS26A,IL22RA1,PARM1,NRP2,SH2D4A,FZD6,M6PR,CD109,TBC1D31,ALPP,CDK16,GTF2F2,TFAP2A,FAM63A,SGK1,TRIM21,HMGCL,SYK,WBP5,P2RX4,HES1,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,RNPEP,TXNDC11,DGKE,BCL10,USP6,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,VANGL1,TSC22D3,CUL1,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,POLL,PIK3CA,TACSTD2,MARCH2,ZBTB18,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,SCOC,DHPS,THEMIS2,PRKAA1,AKAP17A,APBA1,HERC6,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,VASN,RPL39,TPST1,DAPK1,DLX4,ZNF117,GID8,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,JADE2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,WDR19,ZDHHC20,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,SPRED1,GPR107,REPS2,CAPN12,TCTN2,DLGAP5,ST14,THRA,CCDC110,NDRG1,RALBP1,CERCAM,FTH1,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,RAD17,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,TSPAN18,SLC27A3,AREL1,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,CBLL1,NES,DNAH3,ADGRB2,HLA-A,CKAP5,GOLGA2P5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,PAPD7,TCFL5,FBXO9,YES1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,MELK,UGT8,COMMD5,SLC8B1,ERP29,MAP1LC3B,ECI1,HTR1D,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,CERS2,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,ASB9,TEC,QSOX2,SPP1,B3GALNT1,FAM20C,SRP54,NPTN,HLA-C,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,PDIK1L,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,FAM214B,HDAC11,SOD2,OSR2,EXT2,MXD1,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,CD40,TMTC2,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,CIT,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,SYDE2,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,SLC35A1,RPGR,RBMS2,B3GALT6,CFAP46,NADK2,RUNX3,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CTSV,CSGALNACT1,MCUR1,PLOD3,CEP41,AHR,CD33,ABCG1,DOC2A,TRIM24,ADD1,AASS,MRPS15,FBXO2,MMADHC,XIAP,DHX8,IL18,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,RGS12,PSMD1,PQLC2,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SMARCA2,VPS11,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,OSMR,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,TUBB4B,GALNT12,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,PXYLP1,IRS2,SIPA1L1,INPP4B,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,TMA16,NUCB2,KCNC4,GSTP1,HOXB2,TIPRL,NEO1,PDIA4,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,WWP1,MAPK11,SGCB,S100A6,CRTAP,MOB4,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,MYL9,CUL4B,SUDS3,NDC80,MCCC1,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,PXMP4,TLN2,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,CDK1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,PAK2,TMEM8A,PSMA5,ABCC1,CYP26B1,CHSY3,MRPS33,WDR72,TCF7,IFIT3,SMN1,MAPKAPK2,COQ10A,PVRL2,MFSD2A,ITGA7,LTBP2,TMEM120A,IFI6,NIPA1,RNF146,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,SLC7A2,CCNL1,FAM198B,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,GM2A,DVL2,CTH,CPD,EVA1A,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ANXA9,ZBTB6,LTA4H,NDST3,POMGNT2,CNEP1R1,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,CRABP2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,DLGAP1,HMMR,PSMB4,PPARA,CAPNS1,TRIM35,BORA,MAPK8IP1,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,PKD2,ACADM,SAT2,SUN1,GAA,FAM129B,TAP1,PPFIBP2,GATA3,PLA2G16,FAM101B,CENPN,NCS1,CHST2,ELMO2,IQCE,RGS3,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AGO4,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,ITGA3,PIK3AP1,SLC16A6,BDH1,SORL1,CD70,TNFRSF12A,RIMS2,TSPAN33,IGSF3,FADS2,QSOX1,MFI2,B9D2,PTPRH,ANO6,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,CDKN2AIP,SEC23A,TMEM43,CAPN6,DMTN,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,EPHA10,FYN,ZNF641,PPP2R5A,STAT1,PPP1CB,SLC27A1,KLF5,MLKL,HS3ST3B1,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,SLC35G2,SPR,SIX4,RND1,FAM111A,PPP1R10,PTEN,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,CTNS,SERPINB5,GRIN2D,GPER1,NCAPG2,ARSB,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,ST13,CPT2,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,DLG1,CAPG,AKR1B1,ANKRD12,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,STRIP2,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,NEIL1,FASTKD1,ADIPOR1,APBA2,PSMC1,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,ZNF432,CA2,FXYD5,FNIP1,ZNF692,KNTC1,RFX5,NCEH1,ACAD8,LRIF1,ALS2CL,DESI2,KDELR1,OXR1,BTN3A2,AMDHD1,BCAR3,XKRX,NUDT16,SLC6A6,UTP14C,PAPD5,PITPNA,FBXW5,KLF7,GAS2L1,SLC25A24,IL15,PSME2,SLC2A8,GMPR,MORC4,MICALL2,PATL2,LRRC45,SVBP,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,AP5M1,DUSP4,SNAPC2,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,MXD3,HSPA13,IQGAP3,SYPL1,SUN2,ADAM17,GCLC,NR4A1,DEPDC4,ASPM,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,MARC1,HNRNPH2,PRCP,DHRS2,TADA2B,UBE2D2,HOXB13,GEM |
| 1.081e-08 | -18.34 | large_cell_carcinoma | COSMIC cancer mutations | large_cell_carcinoma | 877 | 188 | 17775 | 2585 |
GAA,TNK1,ACVR1,SLC25A13,CAMKK1,EPHA4,RET,CAMK1D,CDKN2C,PAK6,DAPK2,WEE1,RPS6KA2,NUP210,CTNNB1,CDKL5,IL6ST,PIK3CA,ATRNL1,TFG,TIAM1,NEB,STK35,ERAP2,PLK1,NEK4,SGCE,MARK1,ACVR1C,ASXL1,PBK,ROR1,AURKB,IDH1,ADRBK2,STK17B,ULK2,PLK2,LIMK1,GNPTAB,MYLK,LRIG1,TDRD7,MAP3K11,MAPK13,RNASEL,SPRY4,CPPED1,PRKAA2,CDK17,FAM169A,PRKAA1,ADCK5,CNTNAP2,MERTK,BMP2K,RB1,IGF1R,FRY,NEK2,DAPK1,MTMR10,PRKCI,PRKG1,MAP3K9,ADCK2,SORL1,ALPK1,PIM1,MAPK7,PHKG2,WDR72,BTNL9,ADCK3,TESK1,STRADB,KIAA1109,EIF2AK1,PDK3,PDIK1L,GNA11,EGFR,RASA1,PDE11A,STK17A,GNAS,DHDH,MAPKAPK2,INSR,HTT,APPL2,ALPK3,AURKA,CDK18,CTSA,NR4A2,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,RAD21,PKD1L2,KIF3C,TCF25,ZSWIM5,HOXB7,GALNT12,SUZ12,RPS6KA1,TP53,TESK2,ERBB2,GRK6,BAHD1,PRKACA,FLT3,DDR1,CDK14,KIF14,PLK4,SMO,STEAP3,NOTCH3,EPHB4,SCYL3,MAP3K3,RIPK2,AKT1,SYNE2,PRKCQ,PKMYT1,MAP3K6,NIN,EPHA10,FYN,JAK1,CDK19,PTK7,STK38,AXL,KIAA1804,NRG1,MLKL,LIFR,MAPK12,PINK1,DYRK3,TAOK2,GNAL,TGFBR1,PKN1,TRIB2,SYDE2,KIF5B,ADRBK1,IRAK1,CDK16,PTEN,CALD1,SGK3,KIAA0319,ARVCF,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,OSGIN1,CASK,ASPM,PIK3R1,YES1,TXK,CD83,FAT4,FGFR2,ACVRL1,CCDC6,ZMIZ1,PLOD3,ATP6V1C1,HIPK3,MELK,GOLGB1,TLL2 |
| 1.081e-08 | -18.34 | lung-carcinoma-large_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-large_cell_carcinoma | 877 | 188 | 17775 | 2585 |
GAA,TNK1,ACVR1,SLC25A13,CAMKK1,EPHA4,RET,CAMK1D,CDKN2C,PAK6,DAPK2,WEE1,RPS6KA2,NUP210,CTNNB1,CDKL5,IL6ST,PIK3CA,ATRNL1,TFG,TIAM1,NEB,STK35,ERAP2,PLK1,NEK4,SGCE,MARK1,ACVR1C,ASXL1,PBK,ROR1,AURKB,IDH1,ADRBK2,STK17B,ULK2,PLK2,LIMK1,GNPTAB,MYLK,LRIG1,TDRD7,MAP3K11,MAPK13,RNASEL,SPRY4,CPPED1,PRKAA2,CDK17,FAM169A,PRKAA1,ADCK5,CNTNAP2,MERTK,BMP2K,RB1,IGF1R,FRY,NEK2,DAPK1,MTMR10,PRKCI,PRKG1,MAP3K9,ADCK2,SORL1,ALPK1,PIM1,MAPK7,PHKG2,WDR72,BTNL9,ADCK3,TESK1,STRADB,KIAA1109,EIF2AK1,PDK3,PDIK1L,GNA11,EGFR,RASA1,PDE11A,STK17A,GNAS,DHDH,MAPKAPK2,INSR,HTT,APPL2,ALPK3,AURKA,CDK18,CTSA,NR4A2,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,RAD21,PKD1L2,KIF3C,TCF25,ZSWIM5,HOXB7,GALNT12,SUZ12,RPS6KA1,TP53,TESK2,ERBB2,GRK6,BAHD1,PRKACA,FLT3,DDR1,CDK14,KIF14,PLK4,SMO,STEAP3,NOTCH3,EPHB4,SCYL3,MAP3K3,RIPK2,AKT1,SYNE2,PRKCQ,PKMYT1,MAP3K6,NIN,EPHA10,FYN,JAK1,CDK19,PTK7,STK38,AXL,KIAA1804,NRG1,MLKL,LIFR,MAPK12,PINK1,DYRK3,TAOK2,GNAL,TGFBR1,PKN1,TRIB2,SYDE2,KIF5B,ADRBK1,IRAK1,CDK16,PTEN,CALD1,SGK3,KIAA0319,ARVCF,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,OSGIN1,CASK,ASPM,PIK3R1,YES1,TXK,CD83,FAT4,FGFR2,ACVRL1,CCDC6,ZMIZ1,PLOD3,ATP6V1C1,HIPK3,MELK,GOLGB1,TLL2 |
| 1.125e-08 | -18.30 | regulation of developmental process | biological process | GO:0050793 | 2113 | 404 | 16441 | 2455 |
ACACB,ACVR1,SSH1,LGR4,TSC22D3,HEXB,RET,CACNA2D2,GATA3,IL18,MORF4L2,PLXNA1,CAMK1D,CCNB1,VASH1,FAM101B,LTBP3,GRM5,NCS1,TP73,CTGF,PIK3CA,DNM2,TACSTD2,SEMA3G,PACSIN1,TIAM1,NEK4,ACVR1C,TFAP2C,LOXL2,SAV1,POR,ULK2,ABR,ENPP1,PLCG1,DNM1L,AREG,PLK2,LIMK1,TBX1,TRAF3IP1,NKD1,BMP1,HDAC1,ITPKA,ARF6,HSPB1,LZTS1,FGD1,SEMA6B,TBC1D1,NUAK1,SOX9,PRKAA1,NOTCH2,ZNRF3,FAM21C,BMP2K,LMNA,MECOM,CALR,ITGA3,CYR61,MEGF8,BHLHE41,VASN,FLRT3,FBXO7,SORL1,TNFRSF12A,MYDGF,MAPK7,RIMS2,GPR161,SOCS5,EPB41L5,MMD,MFI2,ANO6,WHSC1,PLS1,KIF20B,EPHA1,NPHP3,ILK,GNA11,NFIB,RHOB,RASA1,FAS,PTPRF,AP1AR,NCOA3,HTT,SEMA4D,SETD3,CSNK1G1,NAB2,PIAS2,ARAP1,FGD6,AURKA,SFMBT1,EFNA1,GDF11,ARPC2,MAP3K5,RPS6KA3,XDH,ADAMTS16,EGLN1,EHD1,DMPK,IRF1,FOXO6,GRHL2,LFNG,THRA,INPP5D,RPS6KA1,SUZ12,PKP2,EGR3,PRKACA,FLT3,APC2,MNS1,TNFSF9,CCND1,CD46,NOV,SP100,DACT1,TNPO2,CDKN1B,DAB2IP,LGMN,FLOT2,ETV4,TMBIM1,TBC1D10B,SEMA3B,SSH3,RIPK2,DMTN,CLSTN1,HTATIP2,FZD7,FYN,SHROOM3,CORO1C,AXL,WWTR1,SIPA1L1,INPP4B,TRIOBP,STAT1,KLF5,NRG1,RAB29,RGS14,ARNT,COBL,MAPK12,WASF3,CTHRC1,TAOK2,NKX3-1,RBM24,EPS8,FLOT1,PKN1,ETS1,SPR,SRPX2,TEAD3,ICAM1,ADGRB2,SIX4,SGPL1,NEO1,CTNNBIP1,PDCD10,PTEN,KNDC1,CST3,BAX,MAPK11,CITED2,RAG1,GFI1,ITM2C,TTPA,SPRY2,TRIM62,MSH6,TGIF1,RAPGEF2,TCFL5,PIK3R1,GRIN1,FOS,CDK5RAP1,BTG1,PROM1,FGFR2,ACVRL1,NR1D2,TBX18,ERAP1,ITGAV,GPER1,HMGA1,OSR1,ARSB,SHOX2,FOXA1,EMX1,AGRN,EPHA4,PHOSPHO1,HDAC6,PDGFB,SH3KBP1,CTNNB1,NPNT,CDKL5,IL6ST,DPYSL2,DDHD2,ELF5,MITF,DLG1,DUSP10,NTN4,MYH14,CTTN,S100A13,RASGRP1,CYP1B1,SOD1,ASXL1,SYNE3,STRIP2,ITCH,EZR,KLK6,ARHGDIB,EAF2,CDK1,PLEKHB1,RHEB,DPYSL3,IRX3,TBC1D17,GPRC5B,HPSE,HOXA9,SP6,MAFF,MYL12B,GRN,RUNX2,ARAP3,PPP1R12A,LGALS3,SERPINE2,BVES,UBASH3B,ETV5,PHLPP1,FBLN1,CORO1B,BMP2,SPP1,RB1,TIMP1,CA2,GATA2,FAM20C,KIF13B,PRKCI,SUCO,FNIP1,NPTN,C10orf54,WNT3A,NTN1,ZRANB1,CCDC88A,HMG20B,PDE5A,KIAA1109,CDK5R1,SOX13,GNAS,INSR,ITGA7,CSF1,TMEM30A,NFKBIA,FAM213A,JAK3,SEMA3A,TOB1,RARG,GAS2L1,PAX6,NF2,HOXB7,FOXM1,IL15,TP53,ERBB2,P2RX7,IL27RA,OSR2,EMP2,PER2,PDGFA,LMO4,KIF14,BCL6,SMO,VAT1,CDH3,TWIST1,DIXDC1,TMEM64,NOTCH3,DVL2,SIRT1,TIMP2,AKT1,CDC20,CCSAP,CD40,DAG1,ARHGAP35,SOCS3,HSF4,PTGS2,BHLHB9,STAT6,PTK7,EFNA5,IRF7,PLXND1,ABCA1,CTDSP1,BIN1,ANXA3,FBLIM1,PINK1,SORT1,ADGRG1,CIT,SH3D19,ARHGEF7,LRP4,TGFBR1,GDF15,CRABP2,TRIB2,PPP2R3A,FZD6,HDAC9,CD109,BMP7,MYCL,KIAA0319,TFAP2A,H2AFY,IQGAP3,SYK,FAM134C,TLE6,HES1,RHOA,WNT10B,ASPM,PPARA,RGCC,MBNL3,PRICKLE1,RUNX3,BBS2,MAP1B,CD83,CNOT2,HLA-B,DDAH1,FAT4,TWSG1,FGF18,E2F1,PPP2R3C,SOX8,NDFIP1,L1CAM,ABCG1,NGEF |
| 1.173e-08 | -18.26 | GNF2_BUB1B | MSigDB lists | GNF2_BUB1B | 49 | 24 | 17758 | 2588 |
HMMR,PLK1,ZWINT,HJURP,KIF20A,ASPM,CDC20,NDC80,CDCA8,RACGAP1,AURKB,KIF11,FANCI,TOP2A,PCNA,CCNA2,KIF14,AURKA,BUB1,CCNB2,UBE2C,ESPL1,MELK,SMC4 |
| 1.174e-08 | -18.26 | ovary-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-clear_cell_carcinoma | 687 | 154 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,GATA3,NDRG2,CAMK1D,DPP8,ABCD4,PAK6,DAPK2,WEE1,CYP1A1,RPS6KA2,CTNNB1,CDKL5,PAPSS1,PIK3CA,IL1RAP,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,ROR1,AURKB,IDH1,ADRBK2,STK17B,ULK2,PLK2,CELF5,LIMK1,MYLK,MAP3K11,MAPK13,RNASEL,GRN,PRKAA2,BMF,CDK17,PRKAA1,ADCK5,MERTK,BMP2K,RB1,IGF1R,NEK2,MSH2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,SLC12A2,KCTD3,PHKG2,PLEKHA6,ADCK3,TESK1,STRADB,PLS1,EIF2AK1,KIAA1109,PDK3,PDIK1L,EGFR,STK17A,GNAS,MAPKAPK2,INSR,PHLPP2,SLC4A3,PIAS2,ALPK3,AURKA,CDK18,MAP3K5,ARPC2,JAK3,NRBP1,RPS6KA3,DMPK,RPS6KA1,TP53,TESK2,ERBB2,GRK6,PRKACA,DDR1,FLT3,CDK14,UHRF1BP1L,CDH1,PLK4,EPHB4,SCYL3,MYO5B,MAP3K3,RIPK2,AKT1,UTRN,PRKCQ,PKMYT1,TRIM7,MAP3K6,SOCS3,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,LIFR,MAPK12,PINK1,TAOK2,HSP90B1,DYRK3,TGFBR1,PKN1,TRIB2,ADRBK1,OXCT1,IRAK1,PTEN,CDK16,TFAP2A,SGK3,SGK1,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,MSH6,PGM1,CASK,YES1,TXK,FAT4,FGFR2,ACVRL1,HIPK3,MELK |
| 1.187e-08 | -18.25 | neuron projection morphogenesis | biological process | GO:0048812 | 741 | 167 | 16441 | 2455 |
MYL9,EMX1,UGT8,AGRN,EPHA4,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,WEE1,RPS6KA2,PSMD1,SHC3,DPYSL2,PSMC2,DLG1,DNM2,TRPC1,NTN4,MYH14,CTTN,PACSIN1,BTBD3,TIAM1,RASGRP1,ATL1,CELSR2,RNF165,EZR,ULK2,DPYSL3,PLCG1,MAP2,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,PSMD7,CALM3,DUSP5,RAC2,VASP,IGF1R,LRRN2,FLRT3,COL6A1,PAK2,CACNA1D,NCAM1,WNT3A,NTN1,PSMA5,DPYSL5,RGMB,CALM1,KIF20B,EPHA1,ILK,DPYSL4,RANBP9,NFIB,PSMA4,EGFR,RASA1,CDK5R1,RHOB,SEMA4D,MATN2,AURKA,PITPNA,NR4A2,EFNA1,B4GAT1,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,KLF7,SPRED1,PSME2,IQGAP1,RPS6KA1,ERBB2,RASGRP3,PDGFA,ARTN,DACT1,DAB2IP,EPHB4,DLG3,RASGEF1A,ETV4,FRS3,SEMA3B,COL6A2,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,IRS2,EPHA10,FYN,JAK1,SLC9A6,PSMD3,SPTBN5,EFNA5,NRG1,PLXND1,LIFR,COBL,COL9A3,FARP1,ARHGEF11,ARHGEF7,LRP4,FLOT1,PSMD10,COL4A5,PLPPR4,FGF19,EFNB1,ITGA2B,NRP2,NEO1,GBX2,RND1,KIF5B,ANK1,PTEN,BMP7,SGK1,ERBB3,S100A6,CAMK2G,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,FMN1,RAPGEF2,GRIN1,YES1,ABLIM2,MAP1B,CNTNAP1,FGFR2,FGF18,NR4A3,PGRMC1,RYK,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 1.203e-08 | -18.24 | regulation of cell proliferation | biological process | GO:0042127 | 1479 | 297 | 16441 | 2455 |
TRIM24,XIAP,FBXO2,CUL1,GATA3,IL18,CCNB1,VASH1,LTBP3,TP73,CDKN2C,TGFBR3,CTGF,IL31RA,TACSTD2,SMARCA2,ACVR1C,TFAP2C,ICMT,SAV1,SLC25A5,POR,PGF,AREG,TBX1,NOD2,HDAC1,TRAF5,SCN5A,INPPL1,CDKN1C,DHPS,NUAK1,HLA-E,SOX9,PRKAA1,SLC25A27,NOTCH2,MECOM,TFAP4,C9orf69,CALR,RAC2,CYR61,MYDGF,MFI2,CALCRL,KIF20B,EPHA1,ILK,NFIB,STX3,FAS,NCOA3,OSMR,CLMN,GDF11,XDH,IRF1,PLA2G4A,S100A11,INPP5D,NDRG1,SUZ12,PKP2,FTH1,BCL2L1,CD274,EGR3,PRKACA,FLT3,TNFSF9,CCND1,CD46,NOV,CCNA2,TAX1BP3,CDKN1B,DAB2IP,RTKN2,PDE4D,DLG3,CDKN2D,ETV4,RIPK2,SAT1,PRKCQ,FZD7,IRS2,FYN,JAK1,WWTR1,STAT1,NRG1,ARNT,PRKAR1A,CTHRC1,NKX3-1,IGFBP6,NES,PKN1,ETS1,GSTP1,FGF19,EFNB1,HLA-A,SIX4,CTNNBIP1,E2F7,PDCD10,IRAK1,PTEN,GPC3,CST3,PRC1,SGK3,BAX,CD9,IGFBP2,MAPK11,ERBB3,CNOT6L,SPRY2,S100A6,TGIF1,PDGFC,CASK,TCFL5,RAPGEF2,EIF5A2,UBE2A,EMP3,YES1,TXK,GPLD1,BTG1,FGFR2,PRDX3,ACVRL1,TBX18,NR4A3,SERPINB5,ITGAV,GPER1,HMGA1,FZD5,OSR1,CD81,SHOX2,JARID2,EMX1,TNK1,CASP3,CNOT8,NDRG2,TP53I11,PDGFB,TFAP2E,EPCAM,BTG3,RPS6KA2,CTNNB1,IL6ST,MITF,DLG1,AKR1B1,TNFRSF18,ASH2L,ARNT2,SLC39A10,S100A13,CYP1B1,CD55,ING1,ITCH,EAF2,PRKRA,SESN1,OPTN,HPSE,SP6,KLF11,CAPN1,GRN,RUNX2,LGALS3,SERPINE2,ETV5,TEC,FBLN1,BMP2,RB1,TNS3,IGF1R,TIMP1,GATA2,PRKCI,C10orf54,WNT3A,NTN1,CCDC88A,HP1BP3,PDE5A,EIF2AK1,IFIT3,EGFR,TSC1,NUDT16,INSR,FA2H,CSF1,CGREF1,NFKBIA,SH3BP4,EGFL7,JAK3,CTBP1,RARG,TOB1,NF2,IL15,FOXM1,P3H2,TP53,SOD2,ERBB2,COL18A1,OSR2,EMP2,PER2,PDGFA,SRPX,KIF14,FABP6,SMO,BCL6,CDH3,TWIST1,ZBTB49,NOTCH3,EPB41L4B,EGLN3,F2R,DVL2,SIRT1,TIMP2,AKT1,PTPRU,CDC20,CD40,HSF4,PTGS2,PTPRJ,STAT6,PEX2,OVOL1,LIFR,ADGRG1,TGFBR1,JAG2,NRP2,CD109,ADORA1,BMP7,TFAP2A,SGK1,BRD7,KANK2,KLF9,IQGAP3,SYK,HES1,RHOA,ADAM17,WNT10B,HMGN5,NR4A1,ASPM,CRIP2,RGCC,CAPNS1,RUNX3,PRDX4,SCG2,DHRS2,CDCA7L,CTSV,FGF18,E2F1,PKD2,ICOSLG,ZMIZ1,SOX8,NDFIP1,AHR,PTGES,CD33 |
| 1.210e-08 | -18.23 | TANG_SENESCENCE_TP53_TARGETS_DN | MSigDB lists | TANG_SENESCENCE_TP53_TARGETS_DN | 56 | 26 | 17758 | 2588 |
CENPA,KIF20A,PBK,CDC20,PTTG1,KIF23,RACGAP1,NUSAP1,KIF20B,AURKB,BARD1,KIF11,CDK1,MAP1B,TOP2A,CCNA2,PRC1,PLK4,NEK2,BUB1,CENPE,UBE2C,NRGN,CCNB2,SMC4,CTH |
| 1.250e-08 | -18.20 | negative regulation of programmed cell death | biological process | GO:0043069 | 835 | 184 | 16441 | 2455 |
CASP3,ACVR1,GRIK2,TSC22D3,FAM129B,DNAJC3,XIAP,GATA3,PSME1,CAMK1D,BARD1,TP73,EPCAM,PSMD1,CTNNB1,IL6ST,PSMC2,IL31RA,MITF,PIK3CA,TNFRSF18,CTTN,ARNT2,SLC39A10,ANKRD9,PLK1,SOD1,ITCH,BNIP3L,AURKB,SLC25A5,CDK1,POR,ARF4,OPTN,MDK,SLC25A4,PLK2,TBX1,MADD,NOD2,HDAC1,UNC5B,HSPB1,PSMC1,PRKAA2,BMF,LGALS3,ITGA6,SOX9,PRKAA1,PSMD7,SLC25A27,NOTCH2,MERTK,LMNA,MECOM,TIMP1,IGF1R,CYR61,PAK2,MSH2,DAPK1,PRKCI,FNIP1,MYDGF,PIM1,MAPK7,PSMA5,OXR1,FHL2,STRADB,IFIT3,ILK,PSMA4,EGFR,G2E3,RASA1,FAS,SEMA4D,HTT,NFKBIA,AURKA,NR4A2,JAK3,RARG,IFI6,RPS6KA3,RPS6KA1,PSME2,CAST,TP53,SOD2,ERBB2,EGR3,BCL2L1,STIL,IER3,KIF14,PLCG2,BCL6,SMO,CDKN1B,TWIST1,APIP,LGMN,CDKN2D,F2R,TMBIM1,CTH,SIRT1,PPIF,BAG4,RIPK2,AKT1,FIGNL1,HTATIP2,PRKCQ,GLO1,CBL,SOCS3,IRS2,FYN,BHLHB9,AXL,WFS1,PSMD3,TLE1,NRG1,IRF7,AREL1,LIFR,CBX4,ZC3HC1,FAM134B,GCLM,PINK1,HSP90B1,CPEB4,TRAF2,SERPINB9,PSMD10,NES,TGFBR1,GSTP1,ICAM1,SIX4,PDCD10,ADORA1,IRAK1,PTEN,BMP7,TFAP2A,BAX,TMBIM6,KANK2,ERBB3,CITED2,FAIM,RAG1,MAP3K7,SPRY2,DUSP1,RHOA,PSMB4,HMGN5,PLAUR,GCLC,PIK3R1,GRIN1,PELI3,PIM3,MAPK8IP1,BCL10,FGFR2,SCG2,PRDX3,DHRS2,NR4A3,ARRB1,ITGAV,OSR1,SOX8,HIPK3 |
| 1.256e-08 | -18.19 | GAVIN_FOXP3_TARGETS_CLUSTER_P6 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P6 | 90 | 35 | 17758 | 2588 |
LGALS3,SPC25,CDCA3,CDCA8,NUF2,VARS2,KIF2C,CCNB1,SNX9,ICAM1,IL17RB,CCNA2,BMP7,NEK2,CKS1B,BUB1,PLK1,HMMR,KIF20A,FIGNL1,ASPM,PBK,CDC20,NUSAP1,AURKB,CDK1,RASGRP2,CDCA5,ABCB1,AURKA,CENPE,CMPK2,CCNB2,NCAPG2,ACOT7 |
| 1.287e-08 | -18.17 | GNF2_PCNA | MSigDB lists | GNF2_PCNA | 67 | 29 | 17758 | 2588 |
HMMR,ZWINT,DLGAP5,FOXM1,ASPM,CDC20,NDC80,MYBL2,CDCA8,WHSC1,RACGAP1,NUSAP1,KIF11,CDK1,FANCI,PRIM1,TOP2A,PCNA,CCNA2,PRC1,PLK4,MSH2,AURKA,CENPE,CCNB2,ESPL1,MELK,SMC4,CKS2 |
| 1.288e-08 | -18.17 | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | 213 | 63 | 17758 | 2588 |
GRN,LTBP1,CCDC109B,MRC2,RUNX2,IL15RA,IGFBP6,LGALS3,S100A11,ST14,IQGAP1,CAST,CTSB,BLVRB,HEXB,ASL,CTSZ,TGOLN2,MGST2,DSE,SRPX2,PLS3,TYMP,RAC2,SP100,TIMP1,MGAT1,CTSC,AIM1,DRAM1,FXYD5,S100A13,TMBIM1,GCNT1,SYPL1,S100A4,PLAUR,SAT1,FURIN,FHL2,PTGER4,EMP3,PYGL,NPC2,LHFPL2,CASP4,LCP1,IL1R1,ALDH3B1,SWAP70,RBM47,SERPINA1,UAP1,P4HA2,STAT6,WWTR1,PLA2G15,RAB11FIP1,NR4A3,NOD2,MAPK13,LTBP2,CYBRD1 |
| 1.289e-08 | -18.17 | mitotic cell cycle process | biological process | GO:1903047 | 720 | 163 | 16441 | 2455 |
ACVR1,NDC80,XIAP,CUL1,PSME1,CNTROB,KIF2C,CCNB1,SNX9,CENPN,FANCI,TP73,CDKN2C,WEE1,PCNA,PSMD1,NUP210,CNTRL,CEP78,PSMC2,DLG1,DNM2,TUBG1,KIF22,TUBA4A,PLK1,NEK4,CENPA,PBK,PRKAR2B,AURKB,CCNF,ANLN,CDK1,OPTN,PRIM1,PLK2,PPP2R4,KLF11,PSMC1,USH1C,PPP1R12A,PSMD7,KIF23,RACGAP1,GPSM2,LMNA,RB1,SNX18,NEK2,MSH2,KNTC1,NUP85,PSMA5,KIF20A,MYBL2,KIF20B,PSMA4,RASA1,FAM64A,HTT,CDCA5,PAPD5,FAM83D,AURKA,NDE1,CCNB2,NUP58,DMPK,FBXW5,RAD21,CCNE2,DLGAP5,CEP70,SPC25,TUBB4B,FOXM1,ACTR8,PSME2,PTTG1,TP53,NUF2,BCL2L1,PRKACA,STIL,CDK14,IER3,CCND1,CCNA2,SETDB2,KIF14,PLK4,CDKN1B,CDKN2D,PSRC1,CDC20,VPS4B,CDCA2,NUSAP1,PKMYT1,RAD17,CDC25C,PSMD3,TRIOBP,PPP1CB,CHMP4B,RGS14,SGOL1,REEP4,MAD2L1BP,PPP2R2D,CNEP1R1,ZC3HC1,CKAP2,KLHL13,CIT,EPS8,ERCC6L,CDCA3,CDCA8,NES,PSMD10,SPDL1,CKAP5,SAC3D1,TOP2A,E2F7,PTEN,CENPJ,TUBGCP6,PRC1,CKS1B,BUB1,IQGAP3,GFI1,SPRY2,CAMK2G,SMC4,SUN2,ZWINT,RHOA,WNT10B,CENPC,PSMB4,PAPD7,ASPM,KIF11,BORA,SKA1,DCTN6,ABCB1,E2F1,SSNA1,CENPE,GEM,NUP37,CEP41,WDR62,NCAPG2,UBE2C,ESPL1,MELK,USP16 |
| 1.364e-08 | -18.11 | GGGYGTGNY_UNKNOWN | MSigDB lists | GGGYGTGNY_UNKNOWN | 632 | 144 | 17758 | 2588 |
CCNI,TMEM184B,CAMKK1,ARFGEF1,NRG2,C1orf198,MORF4L2,VASH1,DENND2D,PHF1,TSEN34,SH3KBP1,MAGOHB,WEE1,PSMD1,RABEP2,P4HB,TSPAN6,DPYSL2,RGS3,FOSB,MITF,FUT1,TMEM143,POF1B,ARMCX6,SMYD5,LAMP2,ATL1,ACBD3,RNF19B,ULK2,ABR,MDK,TRIM47,DOLPP1,SH2D3C,ATP7B,ZNF367,SLC31A2,FGD1,CDK17,PARP12,ALDH6A1,PPP1R12A,LGALS3,FXYD3,ADCK5,TFAP4,ITGA3,FRY,RALGPS2,LRRN2,PIK3AP1,KCNN4,CD22,FAM13B,NCAM1,TTLL1,CCDC88A,TRAK2,DPYSL5,MGAT4B,STRADB,PLS1,BCL2L13,TP53INP2,PDIK1L,DCP2,PRX,PDE11A,MOSPD3,MAGED2,NCOA3,SLCO4A1,COL13A1,UTP14C,NAB2,MPP2,NXPH4,RARG,RPS6KA3,DOCK9,NCKAP5,CCDC109B,AVPI1,SLC2A4,RALBP1,NDRG1,THRA,CAST,IQGAP1,RHBDL3,TMX4,GRK6,PRR7,SAP130,APLP2,SRPX,FAM46A,WDR44,VAT1,EPB41L4B,NFKB2,ETV4,FAR1,SEMA3B,GPX4,AKT1,FOXJ2,ATP10D,MYL12A,ATP1A1,PAFAH1B3,STAT6,PTK7,OVOL1,KLF5,RGS14,FARP1,HMGN3,TRIB2,EFNB1,ZFX,CDK16,FAM20B,NCOA2,IGDCC4,ACBD5,ADAM17,NR3C1,CRISPLD2,MAP1B,NUCB1,FGFR2,DBI,PLA2G15,RAP2C,NR4A3,FAM117A,SERPINB5,FHL1,OSR1,SHOX2 |
| 1.371e-08 | -18.11 | cell | cellular component | GO:0005623 | 15728 | 2386 | 17570 | 2579 |
HECA,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,SPSB1,GRM5,LYPD5,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,LCP1,ABR,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,SEC61G,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,PPP6R1,MCCC2,REC8,PYM1,FHL2,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,PLIN5,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,C5orf30,MAPK4,MGST2,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,SEPT6,PTPN9,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,SNX12,TRIM7,ZNF618,NFIX,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,DCAF7,ESRP1,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,CTSZ,ZNF219,HDGFRP2,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,KLC3,BAX,IGFBP2,MED22,ACBD5,PVRL4,TACC1,PIK3R1,DUSP23,MRS2,NUB1,PGBD1,RAB3IP,PIM3,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,WDR45B,SRSF9,ACOT7,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,INPP5E,BTG3,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,DZIP1L,TRIM9,PI4K2B,KCNMB4,HOXA9,ARRDC1,KLF11,RUNX2,LMTK3,PARP12,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,EMC2,STRADB,ZSCAN12,PDK3,PRX,CDK5R1,COL13A1,PHLPP2,KBTBD2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,KMT5C,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,CFAP36,ATP13A2,ZNF628,PTPRJ,IDE,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ARFGEF3,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,UBE2J1,IL17RA,ALDH7A1,CPLX1,TSPAN13,ATP2B1,GCNT1,DUSP1,NFE2L3,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,SSH1,HSPG2,LGR4,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,PAK6,HELZ2,TYMP,ANKS6,OSBPL3,PALD1,FOSB,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,SH2D3C,BMP1,NFKBIZ,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,PPP4R1,MSH2,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,EPHA1,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,AGBL5,PIAS2,APPL2,SFMBT1,KLK7,SAMD8,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,PDE4D,OSBPL7,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,MSANTD4,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,ATP1B1,PYGO1,PKMYT1,ASB13,CBL,B3GALNT2,TRIQK,FZD7,CEP162,ACAD10,NGFRAP1,TRIOBP,CBX7,MAMDC2,IGFBP6,DEPDC1,EPS8,HERC5,PLD2,FBXO6,SPDL1,FGF19,EFNB1,COX7A2,WWP2,SCML1,SLC25A36,E2F7,RNF128,GNB5,CD9,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,CPTP,DCTN6,ACADSB,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,ESPL1,DEF6,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,EPCAM,ZFYVE16,HSF2,CASC4,ARHGEF37,METTL7A,CDKL5,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,SUCO,PRKCI,BRAT1,C10orf54,GAD1,ETV7,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,STEAP1,RANBP9,SOX13,UAP1,SPAG7,RAB31,DCUN1D1,CTSA,TOB1,AFAP1,RARG,SNX30,NBPF1,LZTFL1,DYNLRB1,SORBS1,PAX6,PDIA5,COL18A1,IL27RA,MRAS,SAYSD1,PHLDA1,ZNF687,COX14,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CHP1,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ARHGEF7,TGFBR1,NTAN1,SBF1,XPR1,TMEM63A,KIF5B,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,DCAF6,RC3H2,SYBU,RGCC,TTC7A,LEPR,LEMD2,ARHGAP24,CTSL,CASP7,TRIM69,SPINT2,RAP2C,DTX4,UACA,ARRB1,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,CACNA2D2,SMARCAL1,NRG2,LYNX1,CNTROB,MORF4L2,SYTL4,BARD1,PHF1,DAPK2,ZYX,AP1M2,TGFBR3,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,GRID2IP,WDR11,DNM1L,ANKRD6,MYLK,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,ILK,DCP2,CYB5A,STK17A,DHX32,NAAA,NCOA3,MTFMT,SEMA4D,HTT,SETD3,TEX30,ITPR1,AURKA,GSKIP,ALG2,B4GAT1,MAL2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,NUF2,IL13RA1,KTN1,CDS1,CCND1,SCNN1A,RNF220,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,RNF169,SCN3A,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,TRABD2A,PDXK,RGS14,ARNT,TNRC6C,TAOK2,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,DTX3L,CAPN2,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,DCAF10,PITX2,CCDC6,ATXN7L3,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,UNC93B1,TRIM2,AGRN,GNPDA1,EPHA4,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,ANLN,CLCN2,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,UBASH3B,ASAH1,DOCK11,PGAP1,BMP2,GATA2,CMTR2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,KCNAB3,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,CYP26A1,C1orf116,CDK14,RAD23A,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TIMP2,TCEB2,S100A4,CDC20,DUOX1,RTN4RL1,ATP1A1,PSMD3,RPL22,AIFM3,ZNF701,COPG1,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,ADGRG1,RUSC2,GNE,SWI5,PSMD10,NKRF,SIRPA,SLC9A2,PPP2R3A,MTRNR2L1,CEP97,BUB1,HEXIM2,FAIM,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,CARD19,FXR2,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,TMEM50B,NAT1,ZNF214,NETO2,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,CFAP74,ACVR1,PPP4R4,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,RIC1,SESN3,CTGF,ZFP36,IL31RA,STEAP2,AOX1,RCAN3,TFG,XKR8,LAMP2,LOC81691,SNTB2,PBK,CASP9,TNS1,PIF1,GALNT7,SLC17A5,CCNF,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,TBX1,NKD1,SARAF,DHTKD1,EIF4EBP2,TMEM8B,TRAF5,LZTS1,DLAT,KLF2,MRPL44,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,ZNF84,MICB,AMER1,PIP4K2C,CYFIP2,KDM3A,RASA1,FAS,PRKAG2,CSNK1G1,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PLA2G4A,FRMPD3,ELK4,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,RNF182,EGR3,SNN,NUDT12,GNB2,SLC25A35,APLP2,DOK4,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,JAK1,CFAP45,STK26,KIAA1804,NRG1,RAB29,B4GALT3,ATMIN,OTUD5,NUDT6,ARHGEF3,ANKRD13D,SLC16A14,ARL4C,CDCA3,APOBEC3H,TEAD3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,PRC1,SGK3,ATP8B1,ERCC2,CNOT6L,CNPY3,PCCB,SHMT1,CASK,DENND1B,MPP1,TEF,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,SLC25A40,CSTF2,PGM2L1,ETAA1,SLC25A38,CPEB2,OCLN,CAMKK1,HEBP1,UBE2Z,TAF6L,CACNB4,DENND2D,TMC1,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,SUN3,RAB20,NFU1,MYH14,PTPRE,TRIM8,ASCL5,SYNE3,ROR1,TCN2,EDNRA,MDK,CXXC4,ZNF114,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,PIFO,PEX6,ASL,PHLPP1,KCNN4,EBF4,HP1BP3,PARD3B,GYLTL1B,HMG20B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,PLPP3,NFKBIA,CDCA5,RHOBTB2,ALPK3,KIF12,PROM2,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SLC25A48,SS18,ZDHHC12,FRYL,SMO,GOT1,STEAP3,RPN2,APIP,F2R,LOXL1,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,JKAMP,FRMD6,ARMC7,TRMT2B,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CFAP43,CKS1B,BRD7,RAB3B,CENPC,MBNL3,OGDHL,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,ZNF596,SNPH,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,ISOC2,BAIAP3,LACTB2,SNX9,CARD10,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,WBP4,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,PRKAR2B,RNF19B,ARF4,GINS4,PLCG1,CARHSP1,ENPP1,ATP7B,CELF5,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,HPCAL4,RABGGTA,MARCH8,TFAP4,FLII,PAIP2B,ATP5H,MEGF8,RIMS3,FLRT3,FBXO7,RANBP1,PCYOX1,CADPS2,SLAIN2,FAM84B,MYDGF,ZMYM1,MYLIP,ULBP2,DGKG,PHKG2,PAQR7,HPS3,PQLC3,MAPKAPK3,SHARPIN,ERO1A,KIF20B,PSMA4,GNA11,SFXN5,IL1R1,FNTA,APMAP,S100A5,CLMN,STK39,CFAP20,CBX5,NUP58,RUSC1,DOCK9,TPRN,NQO1,LFNG,INPP5D,CD82,PTTG1,APOO,MVB12B,MOCS1,REPS1,APPBP2,RCN1,CDH1,SH3BP1,XYLT2,LRP11,RASGEF1A,DLG3,ETV4,SNX10,MX1,SEC61B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GABARAPL1,ALDH3B1,CCNB3,PNPLA6,ISOC1,MAPK12,TCAF1,MZT1,GCAT,TRAF2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,FAM20B,CST3,RAG1,PARP9,OPLAH,PLSCR1,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,PHC1,ILDR1,LMCD1,DNAJB11,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,PASK,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,PLEKHG6,HS6ST1,KLF12,AGPAT2,ZNF367,KPNA2,TC2N,MYL12B,RRAGD,PRSS8,HJURP,LGALS3,DNAJB2,SLC22A31,PDCL,SORBS3,ADCK5,HES2,RAB6A,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,FAM213A,RAD21,CTDSPL,TP53,P2RX7,BAHD1,EMP2,STIL,PRR7,SYTL2,TMSB15B,TTC21B,PDGFA,WDR44,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,STK38,MMP17,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,LBR,AIP,VPS26A,IL22RA1,PARM1,NRP2,SH2D4A,FZD6,M6PR,CD109,TBC1D31,ALPP,CDK16,GTF2F2,TFAP2A,FAM63A,SGK1,TRIM21,HMGCL,SYK,WBP5,P2RX4,HES1,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,RNPEP,TXNDC11,DGKE,USP6,BCL10,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,VANGL1,TSC22D3,CUL1,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,POLL,PIK3CA,TACSTD2,MARCH2,ZBTB18,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,SCOC,DHPS,THEMIS2,PRKAA1,AKAP17A,APBA1,HERC6,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,VASN,RPL39,TPST1,DAPK1,DLX4,ZNF117,GID8,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,JADE2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,WDR19,ZDHHC20,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,SPRED1,GPR107,REPS2,CAPN12,TCTN2,DLGAP5,ST14,THRA,CCDC110,NDRG1,CERCAM,RALBP1,FTH1,BCL2L1,DDR1,FLT3,EPS8L2,ZFYVE9,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,RAD17,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,TSPAN18,SLC27A3,AREL1,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,CBLL1,NES,DNAH3,ADGRB2,HLA-A,CKAP5,GOLGA2P5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,PAPD7,TCFL5,FBXO9,YES1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,MELK,UGT8,COMMD5,SLC8B1,ERP29,MAP1LC3B,ECI1,HTR1D,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,CERS2,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,ASB9,TEC,QSOX2,SPP1,B3GALNT1,FAM20C,SRP54,NPTN,HLA-C,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,PDIK1L,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,FAM214B,HDAC11,SOD2,OSR2,EXT2,MXD1,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,CD40,TMTC2,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,CIT,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,HDAC9,SYDE2,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,SLC35A1,RPGR,RBMS2,B3GALT6,CFAP46,NADK2,RUNX3,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CTSV,CSGALNACT1,MCUR1,PLOD3,CEP41,AHR,CD33,ABCG1,DOC2A,TRIM24,ADD1,AASS,MRPS15,FBXO2,MMADHC,XIAP,DHX8,IL18,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,RGS12,PSMD1,PQLC2,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,ACOX2,MANF,PIK3CD,TINAGL1,APOBEC3G,ERAP2,SMARCA2,VPS11,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,OSMR,DYSF,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,TUBB4B,GALNT12,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,PXYLP1,IRS2,SIPA1L1,INPP4B,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,TMA16,NUCB2,KCNC4,GSTP1,HOXB2,TIPRL,NEO1,PDIA4,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,WWP1,MAPK11,SGCB,S100A6,CRTAP,MOB4,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,MYL9,CUL4B,SUDS3,NDC80,MCCC1,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,PXMP4,TLN2,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,CDK1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,PAK2,TMEM8A,PSMA5,ABCC1,CYP26B1,CHSY3,MRPS33,WDR72,TCF7,IFIT3,SMN1,MAPKAPK2,COQ10A,PVRL2,MFSD2A,ITGA7,LTBP2,TMEM120A,IFI6,NIPA1,RNF146,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,CCNL1,SLC7A2,FAM198B,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,GM2A,DVL2,CTH,CPD,EVA1A,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,PTK7,ANXA9,ZBTB6,LTA4H,POMGNT2,NDST3,CNEP1R1,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,CRABP2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,DLGAP1,HMMR,PSMB4,PPARA,CAPNS1,TRIM35,BORA,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,PKD2,ACADM,SAT2,SUN1,GAA,FAM129B,TAP1,PPFIBP2,GATA3,PLA2G16,FAM101B,CENPN,NCS1,CHST2,ELMO2,IQCE,RGS3,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AGO4,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,ITGA3,PIK3AP1,SLC16A6,BDH1,SORL1,CD70,TNFRSF12A,RIMS2,TSPAN33,IGSF3,FADS2,QSOX1,MFI2,B9D2,PTPRH,ANO6,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,CDKN2AIP,SEC23A,TMEM43,CAPN6,DMTN,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,EPHA10,FYN,ZNF641,PPP2R5A,STAT1,PPP1CB,SLC27A1,KLF5,MLKL,HS3ST3B1,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,SLC35G2,SPR,SIX4,RND1,FAM111A,PTEN,PPP1R10,CENPJ,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,CTNS,SERPINB5,GRIN2D,GPER1,ARSB,NCAPG2,ESYT2,USP16,JARID2,EXPH5,EMX1,CASP3,ST13,CPT2,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,DLG1,CAPG,AKR1B1,ANKRD12,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,ATL1,TDP1,SOD1,STRIP2,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,NEIL1,FASTKD1,ADIPOR1,APBA2,PSMC1,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,ZNF432,CA2,FXYD5,FNIP1,ZNF692,KNTC1,RFX5,NCEH1,ACAD8,LRIF1,ALS2CL,DESI2,KDELR1,OXR1,BTN3A2,AMDHD1,BCAR3,XKRX,NUDT16,SLC6A6,UTP14C,PAPD5,PITPNA,FBXW5,KLF7,GAS2L1,SLC25A24,IL15,PSME2,SLC2A8,GMPR,MORC4,PATL2,MICALL2,LRRC45,SVBP,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,AP5M1,DUSP4,SNAPC2,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,MXD3,HSPA13,IQGAP3,SYPL1,SUN2,ADAM17,GCLC,NR4A1,DEPDC4,ASPM,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,MARC1,HNRNPH2,PRCP,DHRS2,TADA2B,UBE2D2,HOXB13,GEM |
| 1.373e-08 | -18.10 | GSE7852_LN_VS_THYMUS_TREG_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_DN | 190 | 58 | 17758 | 2588 |
CMAS,LZTFL1,ENO2,LGALS3,CRYM,HEBP1,HAL,TDRKH,GPSM2,FAM101B,C11orf95,PCBP1,SSX2IP,MXD1,PARM1,PCNA,RGS12,TGFBR3,CTSC,CASC4,TSPAN6,LMO4,MCF2L,KCNK5,FUT8,PAPSS1,ATRNL1,DUSP10,H2AFY,NTN4,STT3B,AK3,SEPHS1,PCGF5,IFITM3,EZR,PRICKLE1,PYGL,TCF7,NUSAP1,FAM133B,PRKAR2B,PRKRA,ICMT,BCL2L13,PTGFRN,TCEAL8,PTPRF,PI4K2B,MAMDC4,RCBTB2,PTER,C1orf21,KPNA2,FHL1,ACOT7,CYBRD1,PRKAR1A |
| 1.430e-08 | -18.06 | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | 393 | 99 | 17775 | 2585 |
TNK1,ACVR1,RPS6KA1,RET,DGKA,ETNK1,TP53,ERBB2,PDGFRL,GRK6,PRKACA,FLT3,DDR1,CDK14,WEE1,RPS6KA2,CTNNB1,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,TFG,DLG3,SCYL3,SEPHS1,NEK4,MAP3K3,RFK,AKT1,PBK,ATP1B1,AURKB,PRKRA,MAP3K6,LCP1,FYN,FASTKD1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,PDXK,LIFR,HOXC13,MAPK12,PRKAR1A,PINK1,MRC2,CDK17,GNE,NEO1,RB1,IGF1R,IRAK1,CDK16,PFKL,DAPK1,MAP3K9,CKS1B,SGK1,MAPK11,PIM1,ERBB3,PIKFYVE,MAPK7,MAP3K7,SYK,CAMK2G,CASK,ADCK3,PIK3R1,PIP4K2C,AK4,MAML2,EIF2AK1,PDK3,YES1,EGFR,MAPK8IP1,DCAF10,MAPKAPK2,BTG1,FGFR2,CCDC6,DCK,AURKA,MAP3K5,JAK3,RPS6KA3,DMPK |
| 1.430e-08 | -18.06 | salivary_gland-carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma | 393 | 99 | 17775 | 2585 |
TNK1,ACVR1,RPS6KA1,RET,DGKA,ETNK1,TP53,ERBB2,PDGFRL,GRK6,PRKACA,FLT3,DDR1,CDK14,WEE1,RPS6KA2,CTNNB1,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,TFG,DLG3,SCYL3,SEPHS1,NEK4,MAP3K3,RFK,AKT1,PBK,ATP1B1,AURKB,PRKRA,MAP3K6,LCP1,FYN,FASTKD1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,PDXK,LIFR,HOXC13,MAPK12,PRKAR1A,PINK1,MRC2,CDK17,GNE,NEO1,RB1,IGF1R,IRAK1,CDK16,PFKL,DAPK1,MAP3K9,CKS1B,SGK1,MAPK11,PIM1,ERBB3,PIKFYVE,MAPK7,MAP3K7,SYK,CAMK2G,CASK,ADCK3,PIK3R1,PIP4K2C,AK4,MAML2,EIF2AK1,PDK3,YES1,EGFR,MAPK8IP1,DCAF10,MAPKAPK2,BTG1,FGFR2,CCDC6,DCK,AURKA,MAP3K5,JAK3,RPS6KA3,DMPK |
| 1.430e-08 | -18.06 | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | 393 | 99 | 17775 | 2585 |
TNK1,ACVR1,RPS6KA1,RET,DGKA,ETNK1,TP53,ERBB2,PDGFRL,GRK6,PRKACA,FLT3,DDR1,CDK14,WEE1,RPS6KA2,CTNNB1,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,TFG,DLG3,SCYL3,SEPHS1,NEK4,MAP3K3,RFK,AKT1,PBK,ATP1B1,AURKB,PRKRA,MAP3K6,LCP1,FYN,FASTKD1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,PDXK,LIFR,HOXC13,MAPK12,PRKAR1A,PINK1,MRC2,CDK17,GNE,NEO1,RB1,IGF1R,IRAK1,CDK16,PFKL,DAPK1,MAP3K9,CKS1B,SGK1,MAPK11,PIM1,ERBB3,PIKFYVE,MAPK7,MAP3K7,SYK,CAMK2G,CASK,ADCK3,PIK3R1,PIP4K2C,AK4,MAML2,EIF2AK1,PDK3,YES1,EGFR,MAPK8IP1,DCAF10,MAPKAPK2,BTG1,FGFR2,CCDC6,DCK,AURKA,MAP3K5,JAK3,RPS6KA3,DMPK |
| 1.430e-08 | -18.06 | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | 393 | 99 | 17775 | 2585 |
TNK1,ACVR1,RPS6KA1,RET,DGKA,ETNK1,TP53,ERBB2,PDGFRL,GRK6,PRKACA,FLT3,DDR1,CDK14,WEE1,RPS6KA2,CTNNB1,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,TFG,DLG3,SCYL3,SEPHS1,NEK4,MAP3K3,RFK,AKT1,PBK,ATP1B1,AURKB,PRKRA,MAP3K6,LCP1,FYN,FASTKD1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,PDXK,LIFR,HOXC13,MAPK12,PRKAR1A,PINK1,MRC2,CDK17,GNE,NEO1,RB1,IGF1R,IRAK1,CDK16,PFKL,DAPK1,MAP3K9,CKS1B,SGK1,MAPK11,PIM1,ERBB3,PIKFYVE,MAPK7,MAP3K7,SYK,CAMK2G,CASK,ADCK3,PIK3R1,PIP4K2C,AK4,MAML2,EIF2AK1,PDK3,YES1,EGFR,MAPK8IP1,DCAF10,MAPKAPK2,BTG1,FGFR2,CCDC6,DCK,AURKA,MAP3K5,JAK3,RPS6KA3,DMPK |
| 1.430e-08 | -18.06 | upper_aerodigestive_tract-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-carcinoma | 393 | 99 | 17775 | 2585 |
TNK1,ACVR1,RPS6KA1,RET,DGKA,ETNK1,TP53,ERBB2,PDGFRL,GRK6,PRKACA,FLT3,DDR1,CDK14,WEE1,RPS6KA2,CTNNB1,PAPSS1,DLG1,PIK3CA,EPHB4,PIK3CD,TFG,DLG3,SCYL3,SEPHS1,NEK4,MAP3K3,RFK,AKT1,PBK,ATP1B1,AURKB,PRKRA,MAP3K6,LCP1,FYN,FASTKD1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,PDXK,LIFR,HOXC13,MAPK12,PRKAR1A,PINK1,MRC2,CDK17,GNE,NEO1,RB1,IGF1R,IRAK1,CDK16,PFKL,DAPK1,MAP3K9,CKS1B,SGK1,MAPK11,PIM1,ERBB3,PIKFYVE,MAPK7,MAP3K7,SYK,CAMK2G,CASK,ADCK3,PIK3R1,PIP4K2C,AK4,MAML2,EIF2AK1,PDK3,YES1,EGFR,MAPK8IP1,DCAF10,MAPKAPK2,BTG1,FGFR2,CCDC6,DCK,AURKA,MAP3K5,JAK3,RPS6KA3,DMPK |
| 1.445e-08 | -18.05 | PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR | MSigDB lists | PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR | 331 | 87 | 17758 | 2588 |
ACVR1,RPS6KA1,DGKA,ETNK1,ERBB2,TESK2,PDGFRL,MAPK4,DDR1,FLT3,DAPK2,RPS6KA2,PIK3CA,PLK4,PHKA2,MAP3K3,NEK4,PLK1,MARK1,RIPK2,AKT1,ACVR1C,PFKFB2,PBK,ROR1,XRCC6BP1,MAP3K6,STK17B,CDK1,PTK7,LIMK1,AXL,STK38,MYLK,MAP3K11,MAPK13,PDXK,ITPKA,MAPK12,GALK1,PINK1,TAOK2,CIT,DGKQ,GNE,TGFBR1,TRIB2,MERTK,NRP2,IGF1R,IRAK1,PFKL,ARSG,PAK2,SGK3,MAP3K9,PRKCI,NEK2,SGK1,MAPK11,PIM1,ERBB3,MAP3K7,PIKFYVE,MAPK7,DGKG,PHKG2,TESK1,MAPKAPK3,STRADB,EIF2AK1,PDK3,ILK,EGFR,DGKE,CDK5R1,STK17A,TXK,MAPKAPK2,INSR,ACVRL1,NR4A3,RYK,MAP3K5,HIPK3,RPS6KA3,DMPK |
| 1.465e-08 | -18.04 | positive regulation of signaling | biological process | GO:0023056 | 1558 | 310 | 16441 | 2455 |
TXN,ACVR1,LGR4,GRIK2,TRIM5,RET,XIAP,NRG2,GATA3,PSME1,IL18,SEPT4,SLC20A1,CARD10,GRM5,TP73,CALM2,PSMD1,TGFBR3,CTGF,IL31RA,PPP1CA,TFG,SH3BGRL,POR,PLCG1,DNM1L,ANKRD6,PLK2,SH2D3C,TBX1,NKD1,FAM110C,NOD2,MAP3K11,TMOD2,UNC5B,TRAF5,F2RL1,GAB1,CDKN1C,SOX9,PRKAA1,NOTCH2,SLC1A3,TNFRSF19,KIAA1161,TFAP4,WDFY1,CYR61,PIK3AP1,MAP3K9,TNFRSF12A,MYDGF,NCAM1,TSPAN33,RIMS2,EEF1D,KLK5,MAPKAPK3,CALM1,AMER1,SHARPIN,ILK,PSMA4,STX3,RASA1,FAS,HTT,SEMA4D,PELI2,ARAP1,EFNA1,GDF11,MAP3K5,RUSC1,XDH,SPRED1,LFNG,BCL2L1,FLT3,NOV,ST5,RNF220,DACT1,DAB2IP,RASGEF1A,NR2C1,CDKN2AIP,RIPK2,FZD4,PFKFB2,DMTN,CLSTN1,PRKCQ,CBL,ITPR3,FZD7,IRS2,FYN,JAK1,AXL,KIAA1804,NRG1,RGS14,ARNT,TAOK2,NKX3-1,TRAF2,EPS8,BIK,FLOT1,PDIA3,PKN1,TSPAN17,FGF19,ICAM1,NEO1,PDCD10,OXCT1,IRAK1,CTSC,PTEN,GPC3,BAX,PLEKHF1,SLC44A2,MAPK11,ERBB3,CITED2,MAP3K7,GFI1,ITM2C,SPRY2,TRIM62,RASGRF1,RAPGEF2,PIK3R1,GRIN1,FURIN,VAMP3,TXK,GPLD1,CNTNAP1,LDLRAP1,FGFR2,ACVRL1,DBI,RYK,GRIN2D,GPER1,LRRK1,FZD5,CD81,SHOX2,FOXA1,ILDR1,EPHA4,LMCD1,ARFGEF1,NENF,HDAC6,PDGFB,ERP29,SPTB,CTNNB1,NPNT,SHC3,IL6ST,TSPAN6,SIVA1,PSMC2,AKR1B1,TNFRSF18,SLC39A10,MYRIP,S100A13,RASGRP1,CYP1B1,SOD1,TRIM8,CXXC5,ASXL1,RNF165,KLK6,PRKRA,CDK1,RHEB,GPRC5B,AGPAT2,HPSE,MADD,PRKCDBP,ADIPOR1,PSMC1,RRAGD,LASP1,BMF,SERPINE2,BVES,RASA2,PSMD7,CALM3,SORBS3,ANO1,IL18R1,DUSP5,BMP2,IGF1R,CA2,KCNN4,PAK2,MDFIC,NPTN,C10orf54,WNT3A,ZRANB1,PSMA5,MDFI,PDE5A,SCRIB,EGFR,GNAS,MAPKAPK2,INSR,CSF1,NLRC5,JAK3,TOB1,RNF146,DRD1,AVPI1,SORBS1,IL15,PSME2,TP53,P2RX7,ERBB2,RASGRP3,EMP2,BCAP31,PDGFA,SRPX,SMO,CDH3,DIXDC1,ECE1,F2R,DVL2,FRS3,CTH,SULF2,MAP3K3,PPIF,SIRT1,TIMP2,BAG4,AKT1,S100A4,CD40,MAP3K6,PTGS2,PTPRJ,PSMD3,SECTM1,CANT1,IRF7,SPTBN5,ARHGAP4,PINK1,CD63,ADGRG1,TAB3,TSPAN15,ARHGEF7,PSMD10,GDF15,TGFBR1,JAG2,PPP2R3A,KIF5B,ADORA1,BMP7,ZDHHC13,BUB1,IQGAP3,SYK,CAMK2G,P2RX4,HES1,RHOA,RAB3B,ADAM17,PSMB4,WNT10B,PLAUR,ASPM,RC3H2,LITAF,MAPK8IP1,BCL10,CD8A,BANK1,TWSG1,FGF18,E2F1,ARRB1,PKD2,NDFIP1,L1CAM |
| 1.501e-08 | -18.01 | VANTVEER_BREAST_CANCER_ESR1_DN | MSigDB lists | VANTVEER_BREAST_CANCER_ESR1_DN | 228 | 66 | 17758 | 2588 |
CCNC,UGT8,UGP2,NF2,IL15RA,ST14,NDRG1,SOD2,MRAS,KIF2C,SNN,STIL,CHST2,APOBEC3B,BTG3,SH3BP1,LMO4,CDH3,STEAP3,PDIA6,LAMP3,TMCC2,CENPA,CYB5R2,CDC20,SLC35C1,ANLN,TCN2,OPTN,GPRC5B,CORO1C,PLEKHG1,PPP1CB,PDXK,BIN1,MPZL1,HJURP,NFKBIE,TBC1D1,HAPLN3,JRKL,CDCA8,GPR180,GPSM2,QSOX2,SIRPA,CTSC,KCNK5,KCNN4,UBE2J1,DAPK1,BUB1,PIM1,PGM1,PLSCR1,MYBL2,TTC7A,PROM1,FAM64A,SLC2A6,NMI,DYSF,ATP1B3,CCNB2,MELK,CSRP2 |
| 1.513e-08 | -18.01 | head_neck | COSMIC cancer mutations | head_neck | 16165 | 2423 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,FHL2,ELK1,NPHP3,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,RAB31,NXPH4,CTSA,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ABRACL,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,SMYD5,XKR8,LAMP2,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,MMD,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,MEGF8,ATP5H,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,TXNRD3NB,KPNA2,TTC39C,TC2N,RRAGD,HS6ST3,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,KIAA0040,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,IL22RA1,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,WHSC1,ANTXR1,NFIB,PDE11A,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,CAPN12,GPR107,REPS2,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,BLCAP,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,SERPINB1,RPS6KA3,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,MAPK11,NKAPP1,WWP1,NPTXR,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,ING1,HN1L,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,TP53I3,ULK2,AHRR,FAM177A1,SLC25A4,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,ZNF75D,CNNM4,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,CCDC74B,ADIPOR1,LEMD1,APBA2,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,LRIF1,ALS2CL,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 1.553e-08 | -17.98 | chrxq22 | MSigDB lists | chrxq22 | 75 | 31 | 17758 | 2588 |
FRMPD3,TBC1D8B,FAM199X,CENPI,TSC22D3,CXorf57,MORC4,PSMD10,DIAPH2,COL4A5,MORF4L2,NUP62CL,TCEAL8,BEX2,MUM1L1,ATG4A,XKRX,TMEM164,RNF128,NGFRAP1,TIMM8A,HNRNPH2,TSPAN6,AMMECR1,TCEAL4,PGRMC1,CSTF2,ACSL4,DRP2,WBP5,NXT2 |
| 1.565e-08 | -17.97 | cell differentiation | biological process | GO:0030154 | 3353 | 605 | 16441 | 2455 |
ADD1,RET,MCOLN3,HEXB,CACNA2D2,CCNO,NRG2,GRM5,TP73,CALM2,NPM2,CDKN2C,WEE1,PSMD1,TGFBR3,PAQR5,RDH14,DNM2,PIK3CD,SEMA3G,TIPARP,TIAM1,SMARCA2,TFAP2C,LOXL2,ARF4,COL12A1,PGF,PLCG1,LIMK1,HDAC1,TMOD2,RNASEL,ITPKA,ARF6,E2F8,SCN5A,ALDH6A1,TMTC3,ITGA6,SOX9,MTL5,GPSM2,MERTK,LMNA,ELF3,RAC2,FRY,FLRT3,MEGF8,ZIC5,NCAM1,MAPK7,DGKG,PAQR7,REC8,ERO1A,SHARPIN,FHL2,KIF20B,ILK,ELK1,TP53INP2,DPYSL4,PSMA4,RHOB,PTPRF,ETS2,SEMA4D,HTT,CLMN,AURKA,B4GAT1,GDF11,ARPC2,NDE1,TRPC3,CSRP2,RPS6KA3,GRHL2,LFNG,APC2,PRKACA,TNFSF9,CCND1,CDH1,DACT1,ACSL4,DLG3,RASGEF1A,SNX10,ETV4,MYT1,SSH3,CAMSAP3,COL6A2,LGALS8,FZD4,HTATIP2,RAB38,TANC1,EBF2,NFIX,IRS2,SHROOM3,SLC9A6,AXL,CORO1C,SIPA1L1,WWTR1,RGS14,ARNT,MAPK12,CTHRC1,FARP1,RBM24,SDC4,CCM2,FLOT1,GMCL1,PLPPR4,ETS1,ICAM1,NEO1,SGPL1,CAPN2,ANK1,IGSF9,KNDC1,GPC3,CST3,BAX,ADAM15,MAPK11,RAG1,SGCB,ITM2C,S100A6,FMN1,TACC1,BCL9,RAPGEF2,PIK3R1,GRIN1,ABLIM2,TXK,PITX2,CNTNAP1,PROM1,ACVRL1,NR4A3,ITGAV,FHL1,OSR1,SHOX2,FOXA1,TLL2,MYL9,TNK1,EPAS1,AGRN,CUL4B,EPHA4,ARFGEF1,NDRG2,F11R,SDC1,PDGFB,SPTB,PLS3,PCNA,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,MITF,PSMC2,ELF5,TMEM143,DUSP10,NTN4,THRB,MARK1,CELSR2,NFE2L1,EZR,CR2,KLK6,ANLN,ZBTB7B,CLCN2,CDK1,RHEB,DPYSL3,IRX3,HS6ST1,MAP2,MYL12B,MAFF,USH1C,RUNX2,LGALS3,RASA2,PSMD7,RACGAP1,CNTNAP2,IL18R1,BMP2,RB1,DAZAP1,VASP,IGF1R,GATA2,KIF13B,PAK2,WNT3A,NTN1,PSMA5,CYP26B1,DPYSL5,RGMB,TCF7,SCRIB,EIF2AK1,UNC45B,CDK5R1,FOXD2,FA2H,PVRL2,COL13A1,MFSD2A,ITGA7,CSF1,TMEM120A,AKIP1,SEMA3A,CTBP1,HOXB7,NF2,FOXM1,TP53,ERBB2,RASGRP3,SDF4,PER2,PDGFA,TACC2,LMO4,PLCG2,LHX6,PLK4,BCL6,CDH3,NOTCH3,SULF2,SIRT1,TIMP2,AKT1,FIGNL1,S100A4,CDC20,PTGER4,MYL12A,DAG1,PTGS2,PTPRJ,RTN4RL1,PTK7,PSMD3,EFNA5,RPL22,LTA4H,POMGNT2,CTDSP1,BIN1,COL9A3,DYRK3,CD63,ADGRG1,CTSB,PSMD10,GDF15,JAG2,CRABP2,NRP2,PPP2R3A,GBX2,CD109,CDK16,TFAP2A,UBE2J1,SGK1,SYK,TLE6,FAM134C,CAMK2G,HES1,RHOA,PSMB4,STMN3,COL7A1,FNDC3A,BBS2,CNOT2,FAT4,TWSG1,FGF18,PGRMC1,ACVR1,LGR4,SSH1,HSPG2,GATA3,PSME1,CAMK1D,PLXNA1,CCNB1,SEPT4,FAM101B,NCS1,PICK1,TYMP,CYP1A1,CTGF,IL31RA,PACSIN1,ZBTB18,ACVR1C,CASP9,SAV1,ULK2,ARHGEF26,SFXN1,HLF,AREG,PLK2,PTER,TBX1,NKD1,BMP1,DHTKD1,UNC5B,F2RL1,LZTS1,KLF2,SEMA6B,MRC2,CDKN1C,SLC1A3,NOTCH2,HERC6,KIAA1161,MECOM,CALR,ITGA3,CYR61,BHLHE41,MSH2,PRKG1,SORL1,TNFRSF12A,CACNA1D,RIMS2,EPB41L5,SPATA20,MMD,DCHS1,AMER1,CALM1,EPHA1,KDM3A,ANTXR1,NFIB,STX3,RASA1,FAS,MMP15,NAB2,MATN2,FAM83D,SFMBT1,NR4A2,EFNA1,HOOK1,EHD1,IRF1,ELK4,FOXO6,SPRED1,SLC2A4,ST14,RPS6KA1,CAST,IQGAP1,THRA,NDRG1,BCL2L1,FLT3,NOV,DAB2IP,PDE4D,EPHB4,SEMA3B,DMTN,FOXJ2,SLC11A2,PRKCQ,PYGO1,ALCAM,FZD7,CMTM7,EPHA10,FYN,JAK1,STAT1,KLF5,RAB29,NRG1,COBL,PRKAR1A,WASF3,PBX3,SPR,FGF19,EFNB1,SIX4,TEAD3,RND1,E2F7,PTEN,CD9,ATP8B1,TAGLN2,ERCC2,ERBB3,CITED2,GFI1,SPRY2,OSGIN1,FARP2,RASGRF1,TGIF1,ARHGEF28,B3GNT2,TCFL5,VAMP3,DIAPH2,C1GALT1C1,FBXO9,YES1,FOS,GPLD1,CDK5RAP1,FGFR2,PRDX3,TBX18,RYK,ERAP1,GRIN2D,GPER1,LRRK1,WDR62,FZD5,ARSB,SLC25A38,JARID2,RGMA,EXPH5,CASP3,EMX1,UGT8,MPP5,DNER,CACNB4,TMC1,EPCAM,CDKL5,DPYSL2,IMPAD1,DLG1,TRPC1,MYH14,CTTN,BTBD3,RASGRP1,ATL1,SOD1,RNF165,EDNRA,MDK,GPRC5B,TDRD7,PSMC1,NR2C2,GRN,SERPINE2,BVES,ETV5,CALM3,TEC,DUSP5,SPP1,LRRN2,FAM20C,COL6A1,PRKCI,FNIP1,C10orf54,NPTN,ETV7,CCDC88A,MDFI,ELK3,HMG20B,RANBP9,EGFR,FECH,TSC1,ONECUT1,UTP14C,PLPP3,TMEM30A,EGFL7,PITPNA,JAK3,RARG,KLF7,DRD1,PAX6,IL15,PSME2,HDAC11,COL18A1,TDRKH,OSR2,MICALL2,PHLDA1,EXT2,ARTN,KIF14,FRYL,SMO,TWIST1,DIXDC1,NFKB2,HSPA2,FRS3,SOAT1,PTPRU,OSTM1,GLO1,SOCS3,ARHGAP35,HSF4,BFSP1,BHLHB9,STAT6,PEX2,PTBP3,SPTBN5,PLXND1,LIFR,SORT1,ARHGEF11,ARHGEF7,FRMD6,CIT,LRP4,TGFBR1,COL4A5,ITGA2B,HDAC9,KIF5B,TOP2A,LLGL2,MYCL,BMP7,RRBP1,KIAA0319,ACTA2,RPGR,MYO5A,ADAM17,WNT10B,ASPM,NR4A1,RC3H2,RUNX3,NDRG3,FOXL1,MAP1B,ARHGAP24,LEMD2,CD8A,DHRS2,SPINT2,RAP2C,CTSV,HOXB13,ZMIZ1,SOX8,PLOD3,L1CAM,NGEF |
| 1.654e-08 | -17.92 | MARKEY_RB1_ACUTE_LOF_DN | MSigDB lists | MARKEY_RB1_ACUTE_LOF_DN | 219 | 64 | 17758 | 2588 |
LMO7,DLGAP5,NQO1,KIF2C,CCNB1,PCNA,CCNA2,UBE2T,KIF22,TIPARP,CKS2,PLK1,CENPA,FIGNL1,DSTN,CBX6,PTGER4,NUSAP1,ANLN,CCNF,CDC25C,H2AFV,CDK1,PRIM1,RBL1,WWTR1,KPNA2,E2F8,GCLM,SCOC,CKAP2,CDCA3,KIF23,PDIA3,RACGAP1,FBLN1,PSIP1,IGF1R,RANBP1,NEK2,PRC1,CKS1B,AHCY,BUB1,IQGAP3,KANK3,SLC12A2,EPHX1,KIF20A,GCLC,CRIP2,KIF11,C4orf27,FAS,IL1R1,FAM64A,TIMM8A,CDCA5,CDCA7L,E2F1,AURKA,CCNB2,CBX5,RAD21 |
| 1.696e-08 | -17.89 | GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN | 191 | 58 | 17758 | 2588 |
MTM1,HECA,ACVR1,PACSIN2,CTSB,CAST,EPHA4,TMX4,GATA3,CBLL1,TRIB2,KCNC4,ETS1,CORO1B,DAZAP1,ACAP2,ADD3,CTNNB1,TIMP1,CAPG,FAM63A,CDKN1B,TMBIM6,MDFIC,TAGLN2,TIAM1,TRAM1,RASGRP1,UPF3A,PIGC,ELK3,S100A4,DSTN,CRIP2,BLVRA,NPDC1,ALCAM,SESN1,ABR,FAS,IL1R1,MMP15,ATP1A1,RBL1,LRIG1,INPP4B,CSGALNACT1,NETO2,PGRMC1,CAB39,AGFG2,SFMBT1,FAM117A,EIF4EBP2,FHL1,REEP4,AHR,AFAP1 |
| 1.746e-08 | -17.86 | KONG_E2F3_TARGETS | MSigDB lists | KONG_E2F3_TARGETS | 95 | 36 | 17758 | 2588 |
SPC25,DEPDC1,DLGAP5,CDCA3,ERCC6L,RACGAP1,NUF2,KIF2C,CCNB1,PSIP1,TOP2A,FAM111A,CCNA2,UBE2T,PRC1,BUB1,USP1,IQGAP3,PLK1,HMMR,KIF20A,FIGNL1,PBK,CDC20,NUSAP1,CCNF,KIF11,PRIM1,RPL12,RBL1,DCK,CDCA5,AURKA,UBE2C,NCAPG2,MELK |
| 1.773e-08 | -17.85 | MODULE_5 | MSigDB lists | MODULE_5 | 425 | 105 | 17758 | 2588 |
MYL9,BCAM,HSPG2,EPAS1,S100A11,RPS6KA1,TAP1,CACNA2D2,IL13RA1,SDC1,EMP2,IER3,CCND1,EPCAM,ZYX,TYMP,SCNN1A,TGFBR3,SRPX,CAPG,DNM2,TACSTD2,RGS5,NOTCH3,LGMN,TSPAN1,LAMP3,CYP1B1,MX1,CD55,COL6A2,TIMP2,SLC39A8,S100A4,CDA,ARHGDIB,ITPR3,LDB2,ALCAM,CASP4,LCP1,DPYSL3,SOCS3,P4HA2,WFS1,WWTR1,SECTM1,MYLK,STAT1,MAOA,PIK3C2B,PLXND1,PDXK,ARHGAP4,NRGN,MAFF,GRN,ANXA3,PCOLCE,IGFBP6,ITGA6,BLVRB,SELL,ASAH1,SEPP1,DHRS3,FBLN1,TSPAN7,ICAM1,GNS,RAC2,ITGA3,CYR61,CTSC,GATA2,CALD1,GPC3,PPP4R1,COL6A1,PIM1,CITED2,QSOX1,HES1,PLSCR1,MAPKAPK3,NR4A1,PLAUR,CALCRL,EMP3,RHOB,CYB5A,FUCA1,IL1R1,TIMP3,SERPINA1,ETS2,ITPR1,DTX4,RAB31,TCEAL4,CTSA,EFNA1,LTBP2,SERPINB1,IRF1 |
| 1.826e-08 | -17.82 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP | 196 | 59 | 17758 | 2588 |
LZTFL1,EPAS1,BIK,NDC80,P2RX7,ASAH1,TEX2,NUF2,BAIAP3,MNS1,CENPN,CARD10,RSAD1,KCTD9,IL17RB,TTC21B,RCN1,FAM111A,FAM46A,METTL7A,SLC16A6,FRYL,MGAT4A,OSBPL3,PRC1,PLEKHF1,BUB1,ALDH7A1,KNTC1,IFIT1,CNGA1,SYTL3,RASGRP1,CYP1B1,HN1L,FIGNL1,CORO2A,LITAF,WHSC1,NUSAP1,ANLN,CDK1,XKRX,AHRR,IL1R1,HLF,DNM1L,ANKRD6,RCBTB2,MATN2,TRAF3IP1,STAT1,ABCB1,APPL2,NR4A3,NUP37,TTC39C,NCAPG2,SERPINB1 |
| 1.901e-08 | -17.78 | BERENJENO_TRANSFORMED_BY_RHOA_UP | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_UP | 521 | 123 | 17758 | 2588 |
PLA2G4A,CASP3,SORBS1,TXN,DLGAP5,FOXM1,SUZ12,PTTG1,SOD2,TP53,KIF2C,GRK6,CCNB1,FAM101B,PHLDA1,SLC35E4,IER3,CCND1,SS18,CYHR1,PCNA,CCNA2,CTGF,UBE2T,NPNT,PSMC2,CAPG,PLK4,TUBG1,KIF22,RNASEH2A,PTPRE,CKS2,CLCN3,CENPA,FIGNL1,CDC20,PTGER4,EZR,SLC11A2,NUSAP1,AURKB,CCNF,ANLN,CDC25C,ALCAM,CDK1,DPYSL3,PRIM1,PTGS2,CDCA4,RBL1,PLK2,CORO1C,NFKBIZ,KPNA2,E2F8,FAM134B,ANXA3,GCLM,IGFBP6,CKAP2,ITGA6,ARL4C,CDCA8,KIF23,PBX3,RACGAP1,LBR,TOP2A,SPP1,TIMP1,CYR61,PFKL,RANBP1,PRC1,NEK2,BAX,MSH2,MTMR10,CKS1B,H2AFY,BUB1,USP1,AHCY,TAGLN2,IQGAP3,NUP85,SMC4,DUSP1,TGIF1,SHMT1,KIF20A,PLSCR1,PQLC3,HMGN5,NR4A1,ASPM,PLAUR,MYBL2,KIF11,NUBP1,C4orf27,C3orf58,SLC4A4,FAM64A,PVRL2,NR1D2,TIMM8A,DCK,CDCA5,NFKBIA,CDCA7L,E2F1,CSTF2,AURKA,ATP1B3,FHL1,NDE1,CBX5,ACOT7,PKIA,NGEF |
| 1.935e-08 | -17.76 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | 187 | 57 | 17758 | 2588 |
SIGIRR,KLF2,HECA,PNISR,TSC22D3,TMEM41B,HLA-F,EPHA4,TMX4,ARL4C,CCNL1,FAM46C,DNAJB9,TMEM63A,SCML1,MARCH8,RASSF8,ADD3,ENTPD4,FAM46A,TIMP1,LYPD3,MGAT4A,KLF3,FOSB,SORL1,SGK1,CRY2,IFIT1,CITED2,MYLIP,TIPARP,CKAP4,ATP2B1,DUSP1,IFITM3,COQ10B,PIK3R1,RNF11,PTGER4,ITPR3,FNDC3A,FOS,RASGRP2,IRS2,CNOT2,RAB11FIP2,PIAS2,PPP1CB,NR4A2,KLF11,PIK3C2B,APBA2,NR3C2,TOB1,KLF7,PHC1 |
| 1.943e-08 | -17.76 | cell projection | cellular component | GO:0042995 | 1731 | 334 | 17570 | 2579 |
DOC2A,LAMP1,CFAP74,SSH1,GRIK2,KLC2,RET,FBXO2,LGI3,LYNX1,SEPT4,SNX9,PICK1,GRM5,NCS1,CALM2,ANKS6,DNAH6,IQCE,CABP1,SLC46A1,PIK3CA,DNM2,TUBG1,PPP1CA,PACSIN1,NEK4,ORAI2,SPEF2,SGCE,SPATA18,PRKAR2B,ARF4,LCP1,ARHGEF26,PIAS3,PLCG1,GRID2IP,WDR11,PLK2,LIMK1,TRAF3IP1,MYLK,TMOD2,SPRY4,ITPKA,ARF6,F2RL1,LZTS1,FGD1,DDX58,INPPL1,CALB2,STRN4,SLC1A3,MERTK,RAC2,ITGA3,SNX18,FLRT3,TNFRSF12A,CNGA1,GPR161,DNAI1,EPB41L5,CEP89,B9D2,CALM1,SHARPIN,KIF20B,ELK1,NPHP3,ILK,CYFIP2,ANTXR1,GNA11,NFIB,STX3,RASA1,FRMD4B,FAS,PTPRF,IL1R1,GABRD,PLEKHH2,HTT,WDR19,FGD6,AURKA,DYSF,ARPC2,CFAP20,NRBP1,EHD1,TPRN,KIF3C,MTM1,TCTN2,TRIP10,S100A11,IQGAP1,C5orf30,PRKACA,APC2,MNS1,EPS8L2,NOV,SCNN1A,CDH1,DAB2IP,DLG3,FLOT2,DOCK4,DMTN,SEPT6,SYNE2,CYS1,UTRN,CLSTN1,SYP,SLC11A2,TANC1,ALCAM,GABARAPL1,CEP162,CFAP45,WFS1,CORO1C,SLC9A6,SIPA1L1,STAT1,NRG1,RGS14,COBL,PRKAR1A,TTC8,WASF3,FARP1,TAOK2,BACE1,EPS8,ARL4C,FLOT1,PLD2,KCNC4,DNAH3,IFT27,CAPN2,ANK1,ADD3,GNB5,IGSF9,ANKS1B,PTEN,KNDC1,MCF2L,CST3,KLC3,ATP8B1,ADAM15,MAP3K7,SPRY2,S100A6,HCN3,MOB4,RASGRF1,ZWINT,LCA5,CASK,MPP1,RAPGEF2,GRIN1,VAMP3,RAB3IP,AIF1L,FOS,CNTNAP1,RGS9,LDLRAP1,PROM1,SYT7,GRIN2D,SSNA1,ITGAV,GPER1,CPEB2,FOXA1,ACOT7,CYBRD1,EPHA4,NDRG2,UBE2Q1,HDAC6,DNER,MAP1LC3B,TMC1,SH3KBP1,PLS3,RAB15,INPP5E,LRRC6,CTNNB1,CDKL5,IL6ST,DPYSL2,DLG1,AKR1B1,RP2,MYH14,CTTN,TLN2,MYRIP,ATL1,SOD1,FOPNL,EZR,DPYSL3,DZIP1L,IRX3,TRIM9,MDK,KCNK1,MAP2,PIEZO1,NRGN,PIFO,USH1C,LMTK3,ARAP3,BVES,CALM3,NCKAP1,CNTNAP2,DHRS3,SSX2IP,CORO1B,SPP1,VASP,IGF1R,CA2,RINL,OCRL,KIF13B,EXOC8,AHCY,CCDC88A,DPYSL5,SPA17,SPATA13,SCRIB,NUBP1,CDK5R1,RASGRP2,GNAS,TSC1,PHLPP2,SEMA3A,PROM2,DRD1,DYNLRB1,NF2,ERBB2,P2RX7,MICALL2,SDF4,TTC21B,PDGFA,SMO,ESPN,GOT1,SCN2A,SCYL3,CLCN3,TIMP2,MBP,AKT1,S100A4,CCSAP,DAG1,CFAP36,PTGS2,ATP1A1,PTPRJ,SPTBN5,PLXND1,BIN1,ANXA3,PINK1,PACSIN2,SORT1,CPEB4,ADGRG1,POC1B,ARHGEF7,CIT,LRP4,GABRG2,KIF5B,MLPH,ADRBK1,ADORA1,CDK16,MAGEE1,CFAP43,ACTA2,CPLX1,RPGR,CAMK2G,MYO5A,DLGAP1,P2RX4,RHOA,ADAM17,CFAP46,PLAUR,STMN3,AKAP3,FXR2,BBS2,BCAR1,MAPK8IP1,MAP1B,ARHGAP24,KLHL2,SWAP70,CTSV,ARRB1,PKD2,ACADM,CEP41,L1CAM,ARHGEF4,SNPH,NGEF |
| 1.953e-08 | -17.75 | GROSS_HYPOXIA_VIA_ELK3_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_UP | 201 | 60 | 17758 | 2588 |
ARHGAP11A,CASP3,SSH1,HOXB7,TUBB4B,CPT2,DDIT4L,NDC80,ARL4C,RACGAP1,PLXNA1,CCNB1,SLC9A3R2,LGALS3BP,SAC3D1,CDKN2C,CCND1,RGS12,CCNA2,GATA2,DOK4,SMO,AOX1,TRIM21,KANK2,MINPP1,SLC12A2,F2R,SEPHS1,AMOTL2,HES1,CENPA,TIMP2,KIF20A,PBK,CRIP2,MGAT4B,CBX6,KIF1C,TNS1,SRSF5,GNA11,FAS,PIAS3,KDSR,AXL,CORO1C,CSF1,DBI,CDCA5,MAP3K11,ARRB1,EFNA5,KPNA2,NDE1,CD81,CCNB2,UBE2C,ABCG1,EGLN1 |
| 1.959e-08 | -17.75 | GGGAGGRR_V$MAZ_Q6 | MSigDB lists | GGGAGGRR_V$MAZ_Q6 | 2165 | 403 | 17758 | 2588 |
ACVR1,HSPG2,VANGL1,TSC22D3,KLC2,GATA3,IL18,SEPT4,NCS1,PAK6,PHYHIP,SESN3,CTGF,RGS3,CABP1,FOSB,SERINC2,KCNS3,CLDN4,MANF,TINAGL1,PPP1CA,WBP4,LAMP2,SMARCA2,BNIP3L,TMEM151A,TFAP2C,PRKAR2B,TNS1,KIF13A,PNKD,ARF4,COL12A1,PIAS3,CAMK2N2,GDE1,SH2D3C,MAP3K11,BMP1,HDAC1,SERPINI1,SPRY4,ITPKA,ARF6,HSPB1,RTN3,E2F8,HOXC13,FGD1,SCN5A,MRC2,CDK17,STRN4,TSPAN7,HPCAL4,PSIP1,LMNA,RABGGTA,MECOM,TFAP4,ITGA3,PIK3AP1,SLC16A6,VASN,NECAB3,BHLHE41,TNFRSF12A,NCAM1,MAPK7,DLX4,KANK3,DGKG,PHKG2,TSPAN33,DNAI1,KLK5,MMD,DCHS1,SRSF5,EPHA1,ILK,KDM3A,GNA11,RHOB,PDE11A,PTPRF,MAGED2,MMP15,NCOA3,C1orf21,NAB2,ITPR1,ARAP1,AGBL5,MDH1,EFNA1,DMPK,ARMCX3,GRHL2,REPS2,TRIP10,CERCAM,THRA,RHBDL3,ETNK1,FTH1,GRK6,EGR3,APC2,PRKACA,MOCS1,CCND1,ST5,RNF220,SCNN1A,FAM46A,XYLT2,TNPO2,DAB2IP,DLG3,OSBPL7,ETV4,MYT1,SULT2B1,GPX4,DOCK4,AGPS,SYNE2,PANK1,KIF1C,RAD17,RAB38,ALCAM,SNX12,SP4,FZD7,NIN,NFIX,FYN,PDLIM3,NGFRAP1,PPP1CB,NRG1,GEN1,SLC27A3,PRR15,ARNT,MAPK12,PCOLCE,MPZL1,IGFBP6,SLC41A1,BACE1,ARL4C,CDCA3,PBX3,PKN1,HOXB2,EFNB1,SIX4,TEAD3,NEO1,TMCC3,WWP2,CTNNBIP1,AKIRIN1,ZFX,PDCD10,ADD3,ITGB8,PPP1R10,CALD1,GPC3,FUT8,ADAM15,ERBB3,ITM2C,NCOA2,SMC4,MOB4,TGIF1,CASK,BCL9,GRIN1,FURIN,C2orf69,FOS,CRTC2,PITX2,RPL12,KIAA0141,SYT7,CCDC6,PLA2G15,NR4A3,CCDC69,GRIN2D,HMGA1,FZD5,FOXA1,OCLN,CYBRD1,JARID2,PHC1,RGMA,BCAM,FAF2,EPAS1,PPM1J,ARFGEF1,NDRG2,UBE2Z,TP53I11,GALM,CDIPT,SDC1,PIGL,PDGFB,DENND2D,CHPF,PLS3,NKAIN3,MITF,SLC44A1,CAPG,ZNF462,THRB,ATL1,CXXC5,TRIM8,CBX6,TNFAIP8L1,ROR1,IDH1,ZBTB7B,SESN1,PLEKHB1,SEC14L2,IRX3,KDM4D,MDK,ARHGEF19,KLF12,HOXA9,PRKCDBP,ADIPOR1,CTNND1,SP6,GLA,PPP2R5D,HS6ST3,GRN,PRSS8,LASP1,BMF,PARP12,ARAP3,PPP1R12A,ZNF395,CHCHD7,PYROXD2,FXYD3,ETV5,SORBS3,CNTNAP2,ADAMTSL4,B4GALNT1,BMP2,AIM1L,DAZAP1,VASP,IGF1R,LRRN2,KCNN4,PRKCI,RFX5,PIM1,PLCB2,KDELR1,MDFI,ELK3,PCDH1,PLEKHA6,GYLTL1B,VWA1,HMG20B,C3orf58,MUM1L1,RASGRP2,FOXD2,BCAR3,GNAS,TSC1,PVRL2,H1F0,NFKBIA,RAB31,NXPH4,RHOBTB2,SHROOM2,RARG,TOB1,DRD1,RAD21,CCNE2,NCKAP5,KCNAB3,SORBS1,PAX6,HOXB7,UGP2,HDAC11,CTDSPL,TP53,COL18A1,BAHD1,PRR7,C1orf116,CYP26A1,SAP130,ZNF687,SRPX,ARTN,TACC2,LMO4,LHX6,VAT1,GOT1,EPB41L4B,NOTCH3,NFKB2,LMAN1,EBAG9,SULF2,FRS3,MAP3K3,KREMEN2,S100A4,SERTAD3,IGSF8,DUSP4,MAP3K6,PTPRJ,ATP1A1,PTK7,STAT6,PSMD3,VSIG10,EFNA5,ANXA9,C1orf43,ST3GAL1,ABCA1,CCDC24,POC1B,BLVRB,GNAL,FAM134A,MIER3,GABRG2,COL4A5,GDF15,TRMT2B,TRIB2,AIP,XPR1,H1FX,SLC9A2,GBX2,M6PR,IRF2BPL,CD109,CDK16,BMP7,TRIM3,ARVCF,CKS1B,MXD3,HEXIM2,CLIP2,CAMK2G,HES1,PHF20L1,ADAM17,RHOA,PLAUR,PHLDB3,RUNX3,PELI3,FXR2,NPDC1,TCEAL8,ARHGAP24,HNRNPH2,PRCP,RAP2C,FIBCD1,E2F1,FAM117A,GEM,NDFIP1,SNPH |
| 1.990e-08 | -17.73 | cell projection part | cellular component | GO:0044463 | 893 | 191 | 17570 | 2579 |
CFAP74,GRIK2,KLC2,EPHA4,FBXO2,NDRG2,SEPT4,MAP1LC3B,TMC1,PICK1,GRM5,CALM2,INPP5E,CTNNB1,CDKL5,DNAH6,DPYSL2,SLC46A1,DLG1,DNM2,AKR1B1,TUBG1,RP2,MYH14,PPP1CA,CTTN,PACSIN1,ORAI2,SPEF2,SGCE,SOD1,FOPNL,EZR,PRKAR2B,ARF4,LCP1,DZIP1L,DPYSL3,GRID2IP,MAP2,TRAF3IP1,TMOD2,PIEZO1,SPRY4,ITPKA,ARF6,NRGN,LZTS1,DDX58,PIFO,BVES,CALB2,STRN4,CALM3,NCKAP1,SLC1A3,CNTNAP2,DHRS3,SSX2IP,VASP,ITGA3,SNX18,FLRT3,EXOC8,CNGA1,GPR161,DNAI1,EPB41L5,CEP89,B9D2,CALM1,SPA17,SPATA13,KIF20B,ELK1,ILK,NPHP3,ANTXR1,STX3,CDK5R1,RASGRP2,TSC1,HTT,PHLPP2,WDR19,AURKA,CFAP20,DRD1,EHD1,PROM2,KIF3C,DYNLRB1,NF2,TCTN2,IQGAP1,C5orf30,PRKACA,APC2,MNS1,EPS8L2,TTC21B,SCNN1A,SMO,DAB2IP,ESPN,GOT1,SCN2A,DLG3,CLCN3,TIMP2,MBP,AKT1,DMTN,SEPT6,SYNE2,CYS1,CCSAP,CLSTN1,UTRN,SYP,SLC11A2,TANC1,DAG1,GABARAPL1,CEP162,ATP1A1,PTPRJ,SLC9A6,SIPA1L1,NRG1,SPTBN5,RGS14,COBL,PRKAR1A,TTC8,BIN1,FARP1,PACSIN2,POC1B,ARHGEF7,EPS8,GABRG2,PLD2,KCNC4,IFT27,DNAH3,KIF5B,ANK1,ADD3,ADORA1,PTEN,ANKS1B,KLC3,ATP8B1,CPLX1,MAP3K7,RPGR,SPRY2,CAMK2G,MYO5A,HCN3,DLGAP1,P2RX4,MOB4,RASGRF1,ADAM17,CASK,RHOA,LCA5,CFAP46,PLAUR,GRIN1,STMN3,RAB3IP,AKAP3,AIF1L,BBS2,MAP1B,CNTNAP1,PROM1,SYT7,ARRB1,SSNA1,PKD2,ITGAV,GPER1,CEP41,L1CAM,CYBRD1,ARHGEF4,NGEF |
| 2.059e-08 | -17.70 | cellular response to organic substance | biological process | GO:0071310 | 2021 | 387 | 16441 | 2455 |
ACVR1,TRIM24,SSH1,ADD1,IL15RA,TRIM5,DNAJC3,RET,CUL1,NRG2,GATA3,PSME1,IL18,CCNB1,CALM2,ZYX,CYP1A1,PSMD1,TGFBR3,CTGF,IL31RA,KLF3,FOSB,PIK3CA,DNM2,IRF2,PPP1CA,PIK3CD,TIAM1,IL10RB,TIPARP,CASP9,KDELR3,AGO4,PRKAR2B,POR,ABR,ENPP1,PLCG1,TBX1,NOD2,HDAC1,EIF4EBP2,MAPK13,RNASEL,HSPB1,GAB1,FGD1,KLF2,SEC61G,HLA-E,SOX9,PRKAA1,TNFRSF19,LMNA,TFAP4,CALR,MEGF8,FLRT3,DAPK1,CD70,TNFRSF12A,MYDGF,NCAM1,MAPK7,NUP85,SOCS5,PAQR7,EPB41L5,GFPT1,UFD1L,MAPKAPK3,STAT4,CALM1,ERO1A,SHARPIN,CALCRL,ELK1,KDM3A,PSMA4,RASA1,FAS,IL1R1,NCOA3,FNTA,PRKAG2,ITPR1,DGAT2,OSMR,NR4A2,NUP58,RPS6KA3,TMEM173,EHD1,IRF1,SPRED1,SLC2A4,THRA,RPS6KA1,IQGAP1,WDTC1,IL13RA1,BCL2L1,EGR3,PRKACA,FLT3,GNB2,ZFYVE9,CCND1,ACAP2,CDH1,SP100,RALB,CDKN1B,DAB2IP,PDE4D,IFIT1,OSBPL7,RASGEF1A,NR2C1,MX1,SEC61B,RIPK2,FZD4,DMTN,SYP,SLC11A2,CBL,ITPR3,FZD7,IRS2,FYN,JAK1,CDK19,NGFRAP1,WFS1,AXL,WWTR1,STAT1,PPP1CB,SLC27A1,NRG1,NR3C2,MAPK12,PRKAR1A,ARHGEF3,PLSCR4,TNRC6C,NKX3-1,HSP90B1,TRAF2,FLOT1,HERC5,GSTP1,FGF19,ICAM1,HLA-A,CAPN2,CXCL16,IRAK1,PTEN,MCF2L,FUT8,BAX,CD9,IGFBP2,MAPK11,ERBB3,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,HCN3,RASGRF1,TGIF1,PDGFC,SHMT1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,FOS,GPLD1,TIMP3,PLOD2,FGFR2,RAB11FIP2,ACVRL1,NR1D2,NR4A3,GRIN2D,GPER1,CMPK2,NUP37,OSR1,CD81,CPEB2,RGMA,PHC1,CCNC,CASP3,UGT8,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,TRIM68,SPTB,ZFYVE16,NUP210,RPS6KA2,CTNNB1,NPNT,SHC3,ZCCHC12,IL6ST,PSMC2,AKR1B1,TNFRSF18,IL1RAP,RASGRP1,SP5,CYP1B1,THRB,SOD1,TRIM8,USP18,EZR,PRKRA,VCP,RHEB,DPYSL3,WIPI1,MAP2,MADD,CAB39,ADIPOR1,KPNA2,PSMC1,PPP2R5D,NR2C2,PCSK5,RRAGD,PRKAA2,RUNX2,HLA-F,RASA2,PSMD7,ATP6V1E2,CALM3,PHLPP1,DUSP5,IL18R1,CORO1B,BMP2,IGF1R,PAK2,COL6A1,PRKCI,PIM1,C10orf54,HLA-C,WNT3A,PSMA5,RGMB,STRADB,TCF7,PDK3,IFIT3,EGFR,FECH,GNAS,MAPKAPK2,TSC1,INSR,PHLPP2,CSF1,NFKBIA,SH3BP4,RAB31,YOD1,LTBP2,JAK3,COL16A1,IFI6,RARG,DRD1,GAS2L1,SORBS1,IL15,SLC2A8,PSME2,PDIA5,TP53,ERBB2,P2RX7,IL27RA,RASGRP3,ARHGEF16,PDGFA,ATP6V0B,SMO,TWIST1,GOT1,OAS3,NFKB2,PDIA6,CTDSP2,FRS3,CTH,SIRT1,TIMP2,BAG4,AKT1,ERBB2IP,DUSP4,CD40,CASP4,SOCS3,DUOX1,PTGS2,IDE,ATP1A1,RBL1,STAT6,PTK7,PSMD3,IRF7,SPTBN5,ARHGAP4,LIFR,ABCA1,SORT1,CPEB4,TAB3,ARHGEF11,CTSB,ARHGEF7,SERPINB9,LRP4,GABRG2,PSMD10,TGFBR1,GDF15,IL22RA1,DNAJB9,NRP2,HDAC9,IL17RB,ADRBK1,BMP7,IL17RA,TRIM21,KLF9,IQGAP3,SYK,CAMK2G,MYO5A,DUSP1,P2RX4,ADAM17,RHOA,PSMB4,WNT10B,NR3C1,IFITM3,NR4A1,AMFR,LITAF,PPARA,BBS2,BCAR1,LEPR,CTSL,HLA-B,TWSG1,FGF18,E2F1,ATP6V1C1,PLOD3,TBC1D4,ARHGEF9,ARHGEF4,NGEF |
| 2.115e-08 | -17.67 | CROONQUIST_NRAS_SIGNALING_DN | MSigDB lists | CROONQUIST_NRAS_SIGNALING_DN | 72 | 30 | 17758 | 2588 |
PLK1,ZWINT,CENPA,SPC25,FOXM1,PTTG1,CDC20,NDC80,MYBL2,KIF2C,AURKB,CCNB1,POLD3,STIL,KIF11,CDC25C,CDK1,TOP2A,WEE1,PCNA,CCNA2,PLOD2,PLK4,AURKA,CKS1B,KIF22,HMGA1,CCNB2,UBE2C,SMC4 |
| 2.160e-08 | -17.65 | CERVERA_SDHB_TARGETS_2 | MSigDB lists | CERVERA_SDHB_TARGETS_2 | 108 | 39 | 17758 | 2588 |
CCNE2,SERPINE2,NUAK1,UBASH3B,ESRP1,CYB561,ITPR2,TNFRSF19,HDAC9,SIPA1L2,CYR61,METTL7A,LYPD6,AIM1,TFAP2A,CADPS2,NOTCH3,FAM84B,MOXD1,SLC12A2,IL1RAP,DUSP1,MFI2,PRSS23,MICB,SH3BGRL,COL7A1,STEAP1,LEPR,STK17A,GALNT3,GPRC5B,AREG,NMI,MATN2,CSGALNACT1,SERPINI1,HS3ST3B1,LTBP2 |
| 2.179e-08 | -17.64 | breast | COSMIC cancer mutations | breast | 17278 | 2552 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,ZNF502,TRPC3,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,ULBP2,DGKG,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,PARM1,IL22RA1,VPS26A,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,CAPN12,GPR107,REPS2,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,ARHGAP42,PQLC2,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 2.241e-08 | -17.61 | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN | 197 | 59 | 17758 | 2588 |
CASP3,GCLM,LGALS3,CTSB,PTTG1,NDC80,ETNK1,SMARCAL1,IL27RA,TXNDC9,KIF2C,PLA2G16,HLA-A,M6PR,SPP1,METTL7A,PAPSS1,PPP4R1,PRC1,SRR,DAPK1,CKS1B,HMGCL,PDIA6,GFI1,GM2A,PSMA5,SMC4,LAMP2,DDB2,MLEC,KIF20A,TMEM43,MAPKAPK3,ASPM,CASP9,CDC20,C1GALT1C1,NUSAP1,POLD3,FANCE,IDH1,VCP,PPP2R5A,PRDX3,PRCP,DCUN1D1,RAB11FIP1,PPP1CB,AURKA,GLB1,PIEZO1,PDXK,ATP6V1C1,ZMIZ1,ARPC2,CCNB2,SERPINB1,MELK |
| 2.270e-08 | -17.60 | positive regulation of signal transduction | biological process | GO:0009967 | 1418 | 285 | 16441 | 2455 |
TXN,ACVR1,LGR4,TRIM5,RET,XIAP,NRG2,GATA3,PSME1,IL18,SEPT4,SLC20A1,CARD10,GRM5,TP73,CALM2,PSMD1,TGFBR3,CTGF,IL31RA,PPP1CA,TFG,SH3BGRL,POR,PLCG1,DNM1L,ANKRD6,PLK2,SH2D3C,TBX1,NKD1,FAM110C,NOD2,MAP3K11,TMOD2,UNC5B,TRAF5,F2RL1,GAB1,CDKN1C,SOX9,PRKAA1,NOTCH2,TNFRSF19,KIAA1161,TFAP4,WDFY1,CYR61,PIK3AP1,MAP3K9,TNFRSF12A,MYDGF,NCAM1,TSPAN33,EEF1D,KLK5,MAPKAPK3,CALM1,AMER1,SHARPIN,ILK,PSMA4,RASA1,FAS,HTT,SEMA4D,PELI2,EFNA1,GDF11,MAP3K5,RUSC1,XDH,SPRED1,LFNG,BCL2L1,FLT3,NOV,ST5,RNF220,DACT1,DAB2IP,RASGEF1A,NR2C1,CDKN2AIP,RIPK2,FZD4,DMTN,PRKCQ,CBL,FZD7,IRS2,FYN,JAK1,AXL,KIAA1804,NRG1,ARNT,NKX3-1,TAOK2,TRAF2,EPS8,BIK,FLOT1,PDIA3,PKN1,TSPAN17,FGF19,ICAM1,NEO1,PDCD10,IRAK1,CTSC,PTEN,GPC3,BAX,PLEKHF1,SLC44A2,MAPK11,ERBB3,CITED2,MAP3K7,GFI1,ITM2C,TRIM62,SPRY2,RASGRF1,RAPGEF2,PIK3R1,GRIN1,FURIN,TXK,CNTNAP1,LDLRAP1,FGFR2,ACVRL1,RYK,GRIN2D,GPER1,LRRK1,FZD5,CD81,SHOX2,FOXA1,EPHA4,LMCD1,ARFGEF1,NENF,HDAC6,ERP29,PDGFB,SPTB,CTNNB1,NPNT,SHC3,IL6ST,TSPAN6,SIVA1,PSMC2,AKR1B1,TNFRSF18,SLC39A10,S100A13,RASGRP1,CYP1B1,SOD1,TRIM8,CXXC5,ASXL1,RNF165,KLK6,PRKRA,CDK1,RHEB,GPRC5B,AGPAT2,HPSE,MADD,PRKCDBP,ADIPOR1,PSMC1,RRAGD,LASP1,BMF,RASA2,PSMD7,CALM3,SORBS3,IL18R1,DUSP5,BMP2,IGF1R,KCNN4,PAK2,MDFIC,NPTN,C10orf54,WNT3A,ZRANB1,PSMA5,MDFI,PDE5A,EGFR,GNAS,MAPKAPK2,INSR,CSF1,NLRC5,JAK3,TOB1,RNF146,AVPI1,SORBS1,IL15,PSME2,TP53,P2RX7,ERBB2,RASGRP3,EMP2,BCAP31,PDGFA,SRPX,SMO,CDH3,DIXDC1,F2R,DVL2,FRS3,CTH,SULF2,MAP3K3,PPIF,SIRT1,BAG4,TIMP2,AKT1,S100A4,CD40,MAP3K6,PTGS2,PTPRJ,PSMD3,SECTM1,CANT1,IRF7,SPTBN5,ARHGAP4,PINK1,TAB3,TSPAN15,CD63,ADGRG1,PSMD10,GDF15,TGFBR1,JAG2,PPP2R3A,ADORA1,BMP7,ZDHHC13,BUB1,IQGAP3,SYK,CAMK2G,P2RX4,HES1,RHOA,ADAM17,PSMB4,WNT10B,PLAUR,ASPM,RC3H2,LITAF,MAPK8IP1,BCL10,CD8A,BANK1,TWSG1,FGF18,E2F1,ARRB1,PKD2,NDFIP1,L1CAM |
| 2.293e-08 | -17.59 | ACTGTGA,MIR-27A,MIR-27B | MSigDB lists | ACTGTGA,MIR-27A,MIR-27B | 448 | 109 | 17758 | 2588 |
UNKL,ACVR1,AGRN,ST14,VANGL1,WDTC1,PDIA5,ARFGEF1,UBE2Q1,FAM78A,TRAPPC8,BAHD1,CYP39A1,REPS1,APPBP2,CDS1,PAK6,WEE1,CABP1,PPME1,FOSB,MYT1,CTDSP2,DVL2,FRS3,THRB,CLCN3,NRBF2,PTPN9,PANK1,PTGER4,NKAIN1,GALNT7,TMTC2,PNKD,PDHX,FZD7,EDNRA,SGPP1,NGFRAP1,PLK2,LIMK1,SH2D3C,RAB11FIP1,CAB39,RCAN2,PLXND1,B4GALT3,APBA2,LIFR,ABCA1,NXT2,RMND5A,CPEB4,TAB3,ZCCHC24,CIT,CCM2,MIER3,TGFBR1,PGAP1,DUSP5,NRP2,NEO1,AKIRIN1,CCDC92,GNS,FOXP2,E2F7,ANK1,GATA2,LYPD3,FLRT3,RIMS3,NEK2,MTMR10,WNT3A,SPRY2,ATP2B1,FAM134C,MDFI,GCC2,MMD,LITAF,PPARA,ZKSCAN2,KBTBD8,FAM133B,KDM3A,EGFR,DCP2,MOSPD3,GALNT3,TSC1,SERTAD2,PLEKHH2,INSR,RND3,CSNK1G1,MFSD2A,CSF1,PHLPP2,C1orf21,PGM2L1,SH3BGRL2,STK39,CDK18,AFAP1,PKIA |
| 2.319e-08 | -17.58 | KEGG_PATHWAYS_IN_CANCER | MSigDB lists | KEGG_PATHWAYS_IN_CANCER | 324 | 85 | 17758 | 2588 |
CCNE2,CASP3,EPAS1,RALBP1,RET,XIAP,TP53,ERBB2,BCL2L1,APC2,FLT3,PDGFB,PDGFA,CCND1,DAPK2,CTNNB1,CDH1,RALB,PLCG2,MITF,PIK3CA,SMO,CDKN1B,ARNT2,PIK3CD,TFG,EGLN3,NFKB2,DVL2,AKT1,TCEB2,FZD4,CASP9,CBL,FZD7,PGF,PIAS3,PTGS2,PLCG1,JAK1,STAT1,HDAC1,TRAF5,ARNT,HSP90B1,NKX3-1,ITGA6,TRAF2,TGFBR1,GSTP1,ETS1,FGF19,ITGA2B,FZD6,MECOM,BMP2,RB1,RAC2,ITGA3,IGF1R,PTEN,MSH2,BAX,DAPK1,CKS1B,WNT3A,MSH6,RHOA,WNT10B,PIK3R1,TCF7,FOS,EGFR,FAS,CCDC6,FGFR2,NFKBIA,FGF18,PIAS2,E2F1,PLD1,ITGAV,FZD5,CTBP1,EGLN1 |
| 2.347e-08 | -17.57 | HER-positive_carcinoma | COSMIC cancer mutations | HER-positive_carcinoma | 2074 | 387 | 17775 | 2585 |
FAM171B,PNISR,ACVR1,TRIM24,RET,XIAP,GATA3,NRG2,CARD10,GRM5,PAK6,WEE1,CYP1A1,DNAH6,IQCE,FOSB,PIK3CA,PPP1CA,PIK3CD,TFG,TIAM1,TIPARP,NWD1,SPEF2,ACVR1C,CASP9,PRKAR2B,AURKB,SAV1,PPP1R14C,CCNF,SLC25A5,COL12A1,LCP1,PIAS3,PLCG1,TRIM47,FAM177A1,AREG,PPP2R4,MAP3K11,HDAC1,MAPK13,SPRY4,TRAF5,F2RL1,HSPB1,GAB1,HOXC13,DLAT,INPPL1,NFKBIE,ITGA6,HLA-E,PRKAA1,RAB23,NOTCH2,MERTK,PSIP1,SH3RF2,MECOM,ELF3,RAC2,ZNRF2,CD22,AIM1,FAM13B,NEK2,MSH2,RUNDC3B,USP1,USP38,PIKFYVE,MAPK7,RIMS2,SOCS5,DDB2,GCC2,STAT4,AMER1,SHARPIN,ANO6,WHSC1,CALCRL,ELK1,FBXO10,RHOB,RASA1,FAS,PTPRF,MAGED2,IL1R1,CACHD1,PRKAG2,ETS2,ITPR1,PIAS2,FGD6,AURKA,EFNA1,NDE1,MAP3K5,TRPC3,RPS6KA3,PLA2G4A,ELK4,SPRED1,REPS2,DLGAP5,LFNG,IQGAP1,SUZ12,RALBP1,RNF182,BCL2L1,PRKACA,FLT3,DDR1,KTN1,REPS1,CD46,CCND1,CCNA2,MUC16,CDH1,RALB,DOK4,CDKN1B,EPHB4,RNASEH2A,ETV4,FLOT2,TMCC2,COL6A2,LGALS8,FZD4,AGPS,SEPT6,CLSTN1,UTRN,PRKCQ,PKMYT1,CBL,ITPR3,SP4,FZD7,NIN,EPHA10,IRS2,FYN,PPP2R5A,JAK1,AXL,STAT1,PPP1CB,NRG1,GEN1,ARNT,MAPK12,PRKAR1A,OTUD5,TTC8,IGFBP6,PARP14,CKAP2,TRAF2,BIK,PDIA3,HERC5,PKN1,ETS1,DNAH3,NFAT5,FGF19,SIX4,TMCC3,WWP2,PDIA4,CAPN2,DTX3L,DIRAS3,PDCD10,IRAK1,PTEN,KNDC1,GPC3,SGK3,BAX,ATP8B1,WWP1,IGFBP2,MAPK11,ERCC2,ERBB3,MAP3K7,SPRY2,TPCN1,NCOA2,MSH6,PARP9,ACBD5,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,UBE2A,FURIN,VAMP3,FOS,CNTNAP1,BTG1,PLOD2,CCDC6,FGFR2,RIN3,PPM1H,ARFGAP3,GRIN2D,ETAA1,FZD5,USP16,EXPH5,CASP3,PPM1J,EPHA4,F11R,PDGFB,DNER,KREMEN1,ZFYVE16,RPS6KA2,TM9SF2,CTNNB1,CNTRL,MKRN3,MITF,DUSP10,POF1B,ANKRD12,TLN2,NEB,PLK1,NLRP4,CELSR2,USP18,ACBD3,ITCH,CR2,ROR1,ADRBK2,RHEB,EDNRA,PLCH1,NEIL1,GPRC5B,HOXA9,MADD,PIK3C2B,EPB41L4A,PPP2R5D,TC2N,PRKAA2,LASP1,PARP12,RASA2,ETV5,PSMD7,ABCG2,IL18R1,PGAP1,DUSP5,BMP2,OTUD1,RB1,IGF1R,PRKCI,PIM1,ZRANB1,ELK3,WDR72,USP31,KBTBD8,PDE5A,ZSCAN12,IFIT3,STEAP1,EGFR,G2E3,GLCE,GNAS,MAPKAPK2,TSC1,INSR,OTUD6B,NFKBIA,YOD1,EGFL7,PLD1,JAK3,SEMA3A,RARG,USP43,LMO7,PAX6,ZSWIM5,NF2,UGP2,TP53,ERBB2,RASGRP3,MRAS,CCNL1,MICALL2,STIL,EXT2,CDK14,PDGFA,SS18,FRYL,PLCG2,SMO,BCL6,CDH3,GYS1,TWIST1,NOTCH3,NFKB2,DVL2,MAP3K3,KREMEN2,AKT1,PTPRU,PTGER4,GLO1,CD40,DUSP4,CDC25C,FANCE,CASP4,MAP3K6,SOCS3,RBL1,PTK7,STK38,STAT6,ABCA1,LIFR,KDELC2,TM2D2,FRMD6,TGFBR1,JAG2,SLC9A2,PPP2R3A,FZD6,KIF5B,MYCL,ACTA2,SGK1,BUB1,SYK,RBMS2,DUSP1,HES1,PHF20L1,ADAM17,RHOA,WNT10B,AMFR,RC3H2,OGDHL,MAML2,BCAR1,DGKE,MAPK8IP1,BCL10,USP6,CASP7,RND3,NEIL3,RAP2C,FGF18,DTX4,OTUB2,ARRB1,GEM |
| 2.347e-08 | -17.57 | breast-carcinoma-HER-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-HER-positive_carcinoma | 2074 | 387 | 17775 | 2585 |
FAM171B,PNISR,ACVR1,TRIM24,RET,XIAP,GATA3,NRG2,CARD10,GRM5,PAK6,WEE1,CYP1A1,DNAH6,IQCE,FOSB,PIK3CA,PPP1CA,PIK3CD,TFG,TIAM1,TIPARP,NWD1,SPEF2,ACVR1C,CASP9,PRKAR2B,AURKB,SAV1,PPP1R14C,CCNF,SLC25A5,COL12A1,LCP1,PIAS3,PLCG1,TRIM47,FAM177A1,AREG,PPP2R4,MAP3K11,HDAC1,MAPK13,SPRY4,TRAF5,F2RL1,HSPB1,GAB1,HOXC13,DLAT,INPPL1,NFKBIE,ITGA6,HLA-E,PRKAA1,RAB23,NOTCH2,MERTK,PSIP1,SH3RF2,MECOM,ELF3,RAC2,ZNRF2,CD22,AIM1,FAM13B,NEK2,MSH2,RUNDC3B,USP1,USP38,PIKFYVE,MAPK7,RIMS2,SOCS5,DDB2,GCC2,STAT4,AMER1,SHARPIN,ANO6,WHSC1,CALCRL,ELK1,FBXO10,RHOB,RASA1,FAS,PTPRF,MAGED2,IL1R1,CACHD1,PRKAG2,ETS2,ITPR1,PIAS2,FGD6,AURKA,EFNA1,NDE1,MAP3K5,TRPC3,RPS6KA3,PLA2G4A,ELK4,SPRED1,REPS2,DLGAP5,LFNG,IQGAP1,SUZ12,RALBP1,RNF182,BCL2L1,PRKACA,FLT3,DDR1,KTN1,REPS1,CD46,CCND1,CCNA2,MUC16,CDH1,RALB,DOK4,CDKN1B,EPHB4,RNASEH2A,ETV4,FLOT2,TMCC2,COL6A2,LGALS8,FZD4,AGPS,SEPT6,CLSTN1,UTRN,PRKCQ,PKMYT1,CBL,ITPR3,SP4,FZD7,NIN,EPHA10,IRS2,FYN,PPP2R5A,JAK1,AXL,STAT1,PPP1CB,NRG1,GEN1,ARNT,MAPK12,PRKAR1A,OTUD5,TTC8,IGFBP6,PARP14,CKAP2,TRAF2,BIK,PDIA3,HERC5,PKN1,ETS1,DNAH3,NFAT5,FGF19,SIX4,TMCC3,WWP2,PDIA4,CAPN2,DTX3L,DIRAS3,PDCD10,IRAK1,PTEN,KNDC1,GPC3,SGK3,BAX,ATP8B1,WWP1,IGFBP2,MAPK11,ERCC2,ERBB3,MAP3K7,SPRY2,TPCN1,NCOA2,MSH6,PARP9,ACBD5,RASGRF1,PDGFC,BCL9,RAPGEF2,PIK3R1,UBE2A,FURIN,VAMP3,FOS,CNTNAP1,BTG1,PLOD2,CCDC6,FGFR2,RIN3,PPM1H,ARFGAP3,GRIN2D,ETAA1,FZD5,USP16,EXPH5,CASP3,PPM1J,EPHA4,F11R,PDGFB,DNER,KREMEN1,ZFYVE16,RPS6KA2,TM9SF2,CTNNB1,CNTRL,MKRN3,MITF,DUSP10,POF1B,ANKRD12,TLN2,NEB,PLK1,NLRP4,CELSR2,USP18,ACBD3,ITCH,CR2,ROR1,ADRBK2,RHEB,EDNRA,PLCH1,NEIL1,GPRC5B,HOXA9,MADD,PIK3C2B,EPB41L4A,PPP2R5D,TC2N,PRKAA2,LASP1,PARP12,RASA2,ETV5,PSMD7,ABCG2,IL18R1,PGAP1,DUSP5,BMP2,OTUD1,RB1,IGF1R,PRKCI,PIM1,ZRANB1,ELK3,WDR72,USP31,KBTBD8,PDE5A,ZSCAN12,IFIT3,STEAP1,EGFR,G2E3,GLCE,GNAS,MAPKAPK2,TSC1,INSR,OTUD6B,NFKBIA,YOD1,EGFL7,PLD1,JAK3,SEMA3A,RARG,USP43,LMO7,PAX6,ZSWIM5,NF2,UGP2,TP53,ERBB2,RASGRP3,MRAS,CCNL1,MICALL2,STIL,EXT2,CDK14,PDGFA,SS18,FRYL,PLCG2,SMO,BCL6,CDH3,GYS1,TWIST1,NOTCH3,NFKB2,DVL2,MAP3K3,KREMEN2,AKT1,PTPRU,PTGER4,GLO1,CD40,DUSP4,CDC25C,FANCE,CASP4,MAP3K6,SOCS3,RBL1,PTK7,STK38,STAT6,ABCA1,LIFR,KDELC2,TM2D2,FRMD6,TGFBR1,JAG2,SLC9A2,PPP2R3A,FZD6,KIF5B,MYCL,ACTA2,SGK1,BUB1,SYK,RBMS2,DUSP1,HES1,PHF20L1,ADAM17,RHOA,WNT10B,AMFR,RC3H2,OGDHL,MAML2,BCAR1,DGKE,MAPK8IP1,BCL10,USP6,CASP7,RND3,NEIL3,RAP2C,FGF18,DTX4,OTUB2,ARRB1,GEM |
| 2.347e-08 | -17.57 | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_DN | 165 | 52 | 17758 | 2588 |
GRN,LAMP1,CDS2,INPPL1,LGALS3,ASL,PDIA5,TGOLN2,F11R,PRRG4,SIRPA,SDF4,ICAM1,IER3,APLP2,ATP6V0B,ZYX,IRAK1,P4HB,GALNS,RRBP1,PPP4R1,CAPG,RPN2,CTSD,PDIA6,PTPRE,FLOT2,SLC16A5,S100A6,MYO5A,CKAP4,CYP1B1,CPD,NAGPA,MGAM,PYGL,NPDC1,RNF19B,ALCAM,POR,CYP4F3,STX3,OSBPL2,IL1R1,MAN2A2,HOXA9,PNPLA6,CLMN,NRG1,PLXND1,PDXK |
| 2.354e-08 | -17.56 | organ development | biological process | GO:0048513 | 2766 | 509 | 16441 | 2455 |
GAA,HECA,ACVR1,ADD1,LGR4,HSPG2,AK7,RET,MCOLN3,GATA3,CUL1,NRG2,PLXNA1,SEPT4,CCNB1,FAM101B,CALM2,TP73,CYP1A1,TGFBR3,CTGF,STIM1,ALDH1A3,IL31RA,PIK3CA,CLDN4,TACSTD2,PIK3CD,SEMA3G,PPP1CA,ZBTB18,TIPARP,CPE,SPEF2,SGCE,CASP9,TFAP2C,LOXL2,SAV1,ICMT,LDB2,CCNF,ZFAND5,ARF4,ABR,SFXN1,ENPP1,HLF,AREG,ATP7B,TBX1,TRAF3IP1,NKD1,MYLK,LRIG1,BMP1,HDAC1,DHTKD1,ARF6,F2RL1,GAB1,E2F8,HOXC13,FGD1,SEMA6B,SCN5A,KLF2,INPPL1,CDKN1C,TMTC3,ITGA6,SOX9,SLC25A27,RAB23,NOTCH2,GPSM2,HERC6,MERTK,TNFRSF19,KIAA1161,LMNA,ELF3,MECOM,CALR,ITGA3,CYR61,FLRT3,MEGF8,BHLHE41,PRKG1,MSH2,TMED2,IGSF3,EPB41L5,REC8,SALL4,ANO6,CALM1,SHARPIN,AMER1,DCHS1,FHL2,CALCRL,WHSC1,ILK,NPHP3,NFIB,GNA11,FAS,NCOA3,SEMA4D,HTT,NAB2,FAM83D,DGAT2,PCDH19,NR4A2,EFNA1,GDF11,NDE1,XDH,ADAMTS16,IRF1,EGLN1,TCF25,PAPSS2,GRHL2,ST14,LFNG,THRA,IQGAP1,CAST,RPS6KA1,IRX4,PKP2,BCL2L1,EGR3,DDR1,FLT3,TNFSF9,RCN1,CCND1,APLP2,NOV,CCNA2,CDH1,CNNM4,CDKN1B,DAB2IP,RTKN2,EPHB4,PDE4D,SNX10,ETV4,MYT1,SEMA3B,LGALS8,FZD4,DMTN,UTRN,SLC11A2,PYGO1,EBF2,FZD7,CMTM7,NFIX,IRS2,FYN,PDLIM3,AXL,CORO1C,WFS1,WWTR1,STAT1,PNPLA6,KLF5,NRG1,COBL,ARNT,CBX7,PRKAR1A,MAPK12,CTHRC1,TNRC6C,NKX3-1,CENPI,MAN1A2,SDC4,CCM2,BIK,PBX3,NES,CTSZ,PKN1,PLPPR4,SEPP1,ETS1,HOXB2,FGF19,EFNB1,SIX4,ICAM1,SGPL1,CTNNBIP1,E2F7,ITGB8,OXCT1,PTEN,KNDC1,GPC3,FJX1,CST3,BAX,CD9,ADAM15,ATP8B1,TMBIM6,ERBB3,ERCC2,RAG1,CITED2,GFI1,SGCB,TTPA,SPRY2,FARP2,POU6F1,TGIF1,ADAMTS2,PDGFC,FMN1,TACC1,BCL9,RAPGEF2,PIK3R1,GRIN1,AK4,FOS,CRISPLD2,GPLD1,TXK,CDK5RAP1,PITX2,PROM1,CTNS,DGCR2,PRDX3,ACVRL1,FGFR2,DBI,TBX18,NR4A3,RYK,SERPINB5,FHL1,LRRK1,FZD5,OSR1,WDR62,USF2,SLC25A38,SHOX2,FOXA1,MELK,JARID2,EXPH5,CASP3,EMX1,EPAS1,EPHA4,SUDS3,PHOSPHO1,NDRG2,PLAC1,DNER,SDC1,PDGFB,CACNB4,SPTB,SLC9A3R2,TMC1,PLS3,EPCAM,PCNA,RPS6KA2,CTNNB1,LRRC6,NPNT,DPYSL2,IMPAD1,MITF,ELF5,DLG1,TMEM143,AKR1B1,ASH2L,ARNT2,MYH14,BTBD3,NEB,SP5,CYP1B1,THRB,SOD1,CELSR2,ASXL1,NFE2L1,EZR,CR2,PRKRA,ANLN,IDH1,CLCN2,IRX3,EDNRA,MDK,HS6ST1,HOXA9,TDRD7,TRIM45,NRGN,MAFF,CAPN1,PCSK5,USH1C,RUNX2,SERPINE2,BVES,CALM3,CNTNAP2,NCKAP1,DHRS3,IL18R1,PGAP1,BMP2,RB1,SPP1,TNS3,DAZAP1,CA2,IGF1R,TIMP1,FAM20C,GATA2,FRAS1,PRKCI,FNIP1,WNT3A,NTN1,SLC12A2,ETV7,MDFI,CYP26B1,HMG20B,TCF7,SCRIB,EIF2AK1,UNC45B,C3orf58,CDK5R1,EGFR,BCAR3,MAPKAPK2,MOSPD3,GNAS,FECH,TSC1,ONECUT1,INSR,FA2H,COL13A1,ITGA7,PHLPP2,CSF1,PRPS2,ALPK3,JAK3,SHROOM2,CCNB2,SEMA3A,RARG,DRD1,PAX6,HOXB7,NF2,IL15,FOXM1,TP53,P2RX7,COL18A1,ERBB2,MRAS,OSR2,STIL,PHLDA1,SDF4,PDGFA,TTC21B,SETDB2,ARTN,TACC2,KIF14,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,SMO,CDH3,GYS1,TWIST1,DIXDC1,ECE1,NOTCH3,MINPP1,NFKB2,DVL2,SULF2,SIRT1,MBP,AKT1,PTPRU,OSTM1,S100A4,PTGER4,GLO1,IGSF8,DAG1,SOCS3,ARHGAP35,HSF4,PTGS2,PTPRJ,PAFAH1B3,BFSP1,PTK7,STAT6,OVOL1,PTBP3,TLE1,PLXND1,RPL22,LTA4H,LIFR,ANXA3,COL9A3,DYRK3,CDH22,ADGRG1,CTSB,ARHGEF7,LRP4,AES,TGFBR1,JAG2,NRP2,FZD6,PPP2R3A,GBX2,HDAC9,ZDHHC21,TOP2A,CD109,FOXP2,MDM1,ADRBK1,BMP7,TOX2,TFAP2A,ACTA2,HMGCL,RPGR,SYK,MYO5A,GCNT1,HES1,ADAM17,RHOA,WNT10B,ASPM,CRIP2,RC3H2,PPARA,TTC7A,RUNX3,FAM73B,FNDC3A,BBS2,FOXL1,PRDX4,LEMD2,CD8A,FAT4,TWSG1,DHRS2,CTSV,FGF18,SPINT2,CSGALNACT1,E2F1,ARRB1,PKD2,PPP2R3C,HOXB13,PLOD3,SOX8,ZMIZ1,AHR |
| 2.376e-08 | -17.56 | protein complex binding | molecular function | GO:0032403 | 907 | 195 | 16491 | 2452 |
CASP3,ACVR1,ST13,ADD1,KIF2C,HDAC6,KIF26A,SNX9,PDGFB,MAP1LC3B,SPTB,PICK1,EPCAM,PCNA,TGFBR3,CTGF,STIM1,NPNT,P4HB,DPYSL2,CAPG,DNM2,KIF22,MYH14,TLN2,PLK1,KIFC2,SYNE3,UXT,EZR,KIF13A,VCP,LCP1,ENPP1,MAP2,PLK2,TRAF3IP1,HDAC1,ANXA11,LASP1,MRC2,USH1C,LGALS3,PEX6,ITGA6,DNAJB2,PDCL,STRN4,KIF23,NDUFA4,RACGAP1,NCKAP1,APBA1,FBLN1,CORO1B,CALR,ITGA3,IGF1R,CYR61,KIF13B,ICAM5,FCHO1,MSH2,CCDC88A,HP1BP3,DPYSL5,UFD1L,KIF20A,CORO2A,SHARPIN,PLS1,KIF20B,PKM,ILK,ANTXR1,GNA11,EGFR,PTPRF,GNAS,AP1AR,FNTA,PLPP3,NFKBIA,FAM83D,CABIN1,KIF12,NDE1,ARPC2,SHROOM2,COL16A1,DRD1,GAS2L1,LZTFL1,KIF3C,MTM1,SORBS1,NF2,THRA,IQGAP1,NDRG1,PKP2,MICALL2,PRKACA,DDR1,EMP2,APC2,BCAP31,GNB2,PDGFA,CCND1,NOV,KIF14,DOK4,REEP1,CDKN1B,ESPN,DAB2IP,RNF169,FRS3,CHP1,SIRT1,CAMSAP3,TIMP2,PSRC1,CAPN6,COG2,SYNE2,UTRN,KIF1C,NUSAP1,RAB38,ERBB2IP,ATP1B1,KCTD2,DAG1,GABARAPL1,IRS2,FYN,SHROOM3,CORO1C,TRIOBP,SPTBN5,MLKL,RGS14,REEP4,PCOLCE,ADGRG1,CTSB,TRAF2,GNAL,NES,HMGN3,SPDL1,ITGA2B,HLA-A,ICAM1,KIF5B,ADORA1,PTEN,TUBGCP6,PRC1,CD9,KLC3,BAX,H2AFY,ADAM15,CLIP2,SYK,CRTAP,MSH6,SUN2,LCA5,FBLN5,ADAM17,HMGN5,CTNNAL1,FMN1,AMFR,SYBU,PIK3R1,PPARA,AIF1L,KIF11,SKA1,MAP1B,CDK5RAP1,CTSL,RGS9,LDLRAP1,ACVRL1,CTSV,ARRB1,CENPE,CD81,L1CAM |
| 2.419e-08 | -17.54 | PROVENZANI_METASTASIS_DN | MSigDB lists | PROVENZANI_METASTASIS_DN | 134 | 45 | 17758 | 2588 |
EPAS1,S100A11,ST14,CTSB,BLVRB,CTDSPL,SDC4,ARL4C,NOTCH2,GRK6,TRIB2,S100A2,ANO1,TSEN34,CCND1,RCN1,NAPG,BMP7,PSMC2,TACSTD2,PDE4D,ETHE1,PDIA6,NFE2L3,PDGFC,SOD1,TIMP2,TNIP1,IFITM3,FOXJ2,VAMP3,AK4,KLK6,YES1,F12,EGFR,DDAH1,WIPI1,DHRS2,P4HA2,NMI,SPINT2,PLOD3,TBC1D4,HSPB1 |
| 2.437e-08 | -17.53 | response to organic substance | biological process | GO:0010033 | 2656 | 491 | 16441 | 2455 |
ACVR1,TRIM24,SSH1,ADD1,IL15RA,TRIM5,DNAJC3,RET,FBXO2,CUL1,NRG2,GATA3,PSME1,IL18,CCNB1,TP73,CALM2,ZYX,CYP1A1,SESN3,PSMD1,TGFBR3,CTGF,IL31RA,KLF3,FOSB,STEAP2,PIK3CA,DNM2,CLDN4,IRF2,PPP1CA,MANF,PIK3CD,TIAM1,IL10RB,TIPARP,ACVR1C,CASP9,KDELR3,AGO4,PRKAR2B,F12,POR,ABR,PIAS3,ENPP1,PLCG1,AREG,TBX1,NOD2,HDAC1,EIF4EBP2,MAPK13,RNASEL,HSPB1,GAB1,FGD1,DDX58,KLF2,INPPL1,SEC61G,HLA-E,DGKQ,SOX9,PRKAA1,TNFRSF19,LMNA,TFAP4,CALR,ITGA3,MEGF8,FLRT3,DAPK1,CD70,TNFRSF12A,STT3B,MYDGF,NCAM1,MAPK7,NUP85,EPHX1,SOCS5,PAQR7,EPB41L5,GFPT1,UFD1L,MAPKAPK3,STAT4,MICB,CALM1,ERO1A,SHARPIN,FHL2,CALCRL,ELK1,MEST,KDM3A,PSMA4,RASA1,FAS,MMP15,IL1R1,NCOA3,FNTA,PRKAG2,ITPR1,DGAT2,OSMR,AURKA,NR4A2,TRPC3,NUP58,RPS6KA3,TMEM173,EHD1,IRF1,SPRED1,SLC2A4,NQO1,THRA,RPS6KA1,IQGAP1,WDTC1,IL13RA1,BCL2L1,EGR3,CD274,PRKACA,FLT3,GNB2,ZFYVE9,CCND1,CCNA2,ACAP2,CDH1,SP100,RALB,CDKN1B,DAB2IP,PDE4D,IFIT1,ACSL4,OSBPL7,RASGEF1A,CDKN2D,NR2C1,MX1,SEC61B,COL6A2,RIPK2,FZD4,PFKFB2,DMTN,VPS4B,SYP,PRKCQ,SLC11A2,CBL,ITPR3,FZD7,IRS2,FYN,JAK1,DDOST,CDK19,NGFRAP1,WFS1,AXL,WWTR1,STAT1,PPP1CB,SLC27A1,NRG1,NR3C2,MAPK12,PRKAR1A,OTUD5,ARHGEF3,PLSCR4,TNRC6C,NKX3-1,HSP90B1,TRAF2,EPS8,FLOT1,HERC5,GPR180,FBXO6,ETS1,GSTP1,FGF19,ICAM1,HLA-A,CAPN2,CXCL16,OXCT1,IRAK1,CTSC,PTEN,MCF2L,CST3,FUT8,CD9,BAX,TMBIM6,IGFBP2,MAPK11,ERBB3,CITED2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,HCN3,RASGRF1,TGIF1,PDGFC,SHMT1,PLSCR1,RAPGEF2,PIK3R1,NUB1,GRIN1,FURIN,YES1,FOS,GPLD1,PITX2,RGS9,BTG1,TIMP3,PLOD2,FGFR2,RAB11FIP2,ACVRL1,NR1D2,PRDX3,NR4A3,GRIN2D,GPER1,CMPK2,NUP37,FZD5,OSR1,ARSB,CD81,CPEB2,FOXA1,RGMA,PHC1,CCNC,CASP3,UGT8,FAF2,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,SDC1,TRIM68,SPTB,ZFYVE16,PCNA,NUP210,RPS6KA2,CTNNB1,NPNT,SHC3,ZCCHC12,IL6ST,DPYSL2,PSMC2,ABCA2,AKR1B1,DUSP10,TNFRSF18,ASH2L,ARNT2,IL1RAP,RASGRP1,SP5,CYP1B1,THRB,SOD1,TRIM8,CITED4,ASXL1,USP18,EZR,ERP44,PRKRA,IDH1,VCP,RHEB,DPYSL3,MDK,MAP2,WIPI1,MADD,CAB39,ADIPOR1,KPNA2,PSMC1,PPP2R5D,NR2C2,PCSK5,RRAGD,PRKAA2,GRN,RUNX2,DNAJB2,HLA-F,RASA2,PSMD7,ATP6V1E2,CALM3,PHLPP1,DUSP5,IL18R1,CORO1B,BMP2,SPP1,TIMP1,CA2,IGF1R,PFKL,GATA2,PAK2,COL6A1,PRKCI,PIM1,C10orf54,HLA-C,WNT3A,PSMA5,RGMB,STRADB,TCF7,PDK3,IFIT3,EGFR,FECH,GNAS,MAPKAPK2,TSC1,INSR,PHLPP2,CSF1,NFKBIA,SH3BP4,RAB31,YOD1,LTBP2,JAK3,COL16A1,RARG,IFI6,DRD1,GAS2L1,SORBS1,FOXM1,IL15,SLC2A8,PSME2,PDIA5,TP53,ERBB2,P2RX7,IL27RA,RASGRP3,ARHGEF16,SDF4,PDGFA,ATP6V0B,PLCG2,SRR,SMO,GOT1,TWIST1,OAS3,NFKB2,F2R,PDIA6,LOXL1,CTDSP2,HSPA2,FRS3,CTH,SIRT1,TIMP2,ERLEC1,BAG4,AKT1,PTPRU,PTGER4,ERBB2IP,DUSP4,CD40,CASP4,DAG1,SOCS3,DNAJC10,DUOX1,PTGS2,IDE,ATP1A1,RBL1,PSMD3,STAT6,PTK7,XRCC3,SPTBN5,IRF7,ARHGAP4,LTA4H,ABCA1,LIFR,ANXA3,SORT1,CPEB4,TAB3,ARHGEF11,JKAMP,ARHGEF7,CTSB,SERPINB9,GNAL,LRP4,GABRG2,PSMD10,SELL,TGFBR1,AES,GDF15,IL22RA1,DNAJB9,NRP2,HDAC9,IL17RB,ADRBK1,BMP7,TOX2,TFAP2A,UBE2J1,IL17RA,TRIM21,HMGCL,KLF9,IQGAP3,SYK,CAMK2G,MYO5A,GCNT1,DUSP1,P2RX4,ADAM17,RHOA,PSMB4,WNT10B,NR3C1,IFITM3,AMFR,NR4A1,GCLC,LITAF,PPARA,RUNX3,GGH,BCAR1,BBS2,LEPR,BCL10,CD83,CTSL,HLA-B,TWSG1,CTSV,FGF18,E2F1,HOXB13,ATP6V1C1,PLOD3,TBC1D4,PTGES,ARHGEF9,ABCG1,ARHGEF4,NGEF |
| 2.450e-08 | -17.52 | tissue development | biological process | GO:0009888 | 1601 | 316 | 16441 | 2455 |
GAA,ACVR1,HSPG2,LGR4,RET,MCOLN3,CCNO,GATA3,PLXNA1,CCNB1,FAM101B,CYP1A1,TGFBR3,CTGF,STIM1,ALDH1A3,PIK3CA,TACSTD2,SEMA3G,PPP1CA,ZBTB18,TIPARP,TFAP2C,LOXL2,LDB2,SAV1,ZFAND5,COL12A1,ARHGEF26,LCP1,ENPP1,HLF,AREG,TBX1,PTER,TRAF3IP1,MYLK,BMP1,HDAC1,F2RL1,GAB1,E2F8,HOXC13,SEMA6B,KLF2,TMTC3,ITGA6,SOX9,RAB23,GPSM2,MERTK,TNFRSF19,KIAA1161,LMNA,ELF3,MESDC2,MECOM,CALR,ITGA3,CYR61,MEGF8,FLRT3,EPB41L5,KLK5,SALL4,AMER1,ANO6,SHARPIN,DCHS1,FHL2,KIF20B,NPHP3,MEST,ILK,NFIB,MMP15,NCOA3,ETS2,HTT,SEMA4D,FAM83D,DGAT2,KLK7,EFNA1,GDF11,ADAMTS16,EGLN1,GRHL2,LFNG,ST14,THRA,IQGAP1,PKP2,PRKACA,DDR1,CCND1,NOV,CNNM4,PDE4D,DLG3,FLOT2,ETV4,SEMA3B,FZD4,PRKCQ,FZD7,EBF2,SHROOM3,CORO1C,WWTR1,STAT1,KLF5,NRG1,COBL,PRKAR1A,CTHRC1,TNRC6C,NKX3-1,SDC4,CCM2,CTSZ,FGF19,EFNB1,HOXB2,ICAM1,SIX4,CTNNBIP1,E2F7,PDCD10,OXCT1,ITGB8,PTEN,GPC3,FJX1,CST3,BAX,ADAM15,ERBB3,ERCC2,TAGLN2,MAP3K7,CITED2,SGCB,GFI1,SPRY2,TGIF1,FMN1,BCL9,RAPGEF2,FOS,GPLD1,PITX2,PROM1,TIMP3,ACVRL1,FGFR2,DBI,TBX18,NR4A3,SERPINB5,ITGAV,FZD5,OSR1,SHOX2,FOXA1,EXPH5,EMX1,CASP3,EPHA4,PHOSPHO1,F11R,MPP5,PLAC1,SDC1,DNER,PDGFB,CACNB4,TMC1,PLS3,EPCAM,PCNA,CTNNB1,GRHL1,NPNT,IMPAD1,ELF5,MITF,DLG1,MYH14,CYP1B1,THRB,SOD1,EZR,KLK6,CLCN2,ZBTB7B,CDK1,IRX3,EDNRA,AGPAT2,TDRD7,MAFF,USH1C,RUNX2,LGALS3,SERPINE2,BVES,TEC,NCKAP1,DUSP5,BMP2,SPP1,RB1,VASP,IGF1R,CA2,TIMP1,FAM20C,GATA2,FRAS1,COL6A1,NTN1,WNT3A,SLC12A2,ALDH3A2,HMG20B,SCRIB,C3orf58,EGFR,GNAS,TSC1,ONECUT1,INSR,FA2H,CSF1,ITGA7,SEMA3A,RARG,PAX6,NF2,TP53,ERBB2,COL18A1,OSR2,STIL,EXT2,PDGFA,SETDB2,ARTN,LMO4,SMO,CDH3,TWIST1,MINPP1,DVL2,SULF2,AKT1,S100A4,IGSF8,DUSP4,DAG1,SOCS3,ARHGAP35,PTGS2,BFSP1,PTK7,STAT6,SECTM1,OVOL1,PLXND1,LTA4H,CTSB,FRMD6,LRP4,TGFBR1,JAG2,CRABP2,FZD6,NRP2,PPP2R3A,GBX2,ZDHHC21,CD109,MDM1,BMP7,TFAP2A,ACTA2,RPGR,MYO5A,DUSP1,GCNT1,HES1,ADAM17,RHOA,WNT10B,PPARA,PRICKLE1,RUNX3,COL7A1,FNDC3A,BBS2,FOXL1,BCL10,LEMD2,ARHGAP24,FAT4,TWSG1,CTSV,FGF18,SPINT2,RAP2C,CSGALNACT1,PKD2,HOXB13,PLOD3,SOX8 |
| 2.496e-08 | -17.51 | signal transduction by protein phosphorylation | biological process | GO:0023014 | 413 | 104 | 16441 | 2455 |
SPRED1,ACVR1,RPS6KA1,PSME2,RET,CUL1,ERBB2,NRG2,IL18,MAPK4,RASGRP3,PSME1,PDGFB,SPTB,PDGFA,CALM2,PAK6,RPS6KA2,PSMD1,SHC3,DOK4,PSMC2,IL31RA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,MAP3K3,NEK4,RIPK2,ACVR1C,PTGER4,DUSP4,MAP3K6,IRS2,FYN,JAK1,STK26,SH2D3C,PSMD3,KIAA1804,MAP3K11,NOD2,CAB39,MAPK13,SPTBN5,NRG1,GAB1,PPP2R5D,PSMC1,MAPK12,TAOK2,TAB3,RASA2,SOX9,CCM2,PSMD7,PSMD10,CALM3,TGFBR1,PKN1,TNFRSF19,DUSP5,FGF19,IRAK1,PAK2,MAP3K9,MDFIC,MAPK11,ERBB3,IQGAP3,MAP3K7,NCAM1,MAPK7,SYK,PSMA5,CAMK2G,MDFI,RASGRF1,PSMB4,MAPKAPK3,RAPGEF2,CALM1,GRIN1,STRADB,ELK1,FOS,PSMA4,MAPK8IP1,EGFR,RASA1,MAPKAPK2,INSR,ACVRL1,SCG2,FGFR2,FGF18,STK39,GRIN2D,ITGAV,MAP3K5,JAK3,RPS6KA3 |
| 2.510e-08 | -17.50 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | 518 | 122 | 17758 | 2588 |
AVPI1,CCDC109B,SORBS1,FAF2,AGRN,IL15RA,NQO1,FLYWCH2,TMEM41B,NDRG1,ETNK1,LYNX1,CD274,FAM198B,SLC20A1,CENPN,CMTM6,LTBP3,ABCD4,CHPF,NOV,BTG3,CTGF,SHC3,PHTF1,FOSB,ENPP5,ZBTB49,HYLS1,TINAGL1,PACSIN1,NFKB2,CDKN2D,IL10RB,NEB,TMBIM1,SP5,UPF3A,TIMP2,LGALS8,S100A4,COQ10B,SAT1,UTRN,HTATIP2,EAF2,C15orf39,MCFD2,MFAP3L,ALDH3B1,PTGS2,AREG,PTK7,WFS1,FAM114A1,BMP1,SP6,NFKBIZ,SLC31A2,ANXA3,SERPINE2,FRMD6,RAB23,ASB9,ASAH1,COL4A5,FBXO6,ETS1,TSPAN17,ANO1,TEAD3,BMP2K,AKIRIN1,SPP1,IGF1R,RALGPS2,RNF128,RINL,VASN,PAK2,DRAM1,TRIM3,TNFRSF12A,TSPAN13,HEXIM2,ACAD8,ALDH3A2,SLC35A1,S100A6,HCN3,DUSP1,EPHX1,AMOTL2,P2RX4,QSOX1,FADS2,ZWINT,PRSS23,NR4A1,TEF,BCL9,PLAUR,CRIP2,C1GALT1C1,COL7A1,YES1,NPDC1,ANTXR1,GNA11,MAPK8IP1,FAS,BCL10,FUCA1,TJP3,CGREF1,NMI,ALPK3,SERPINB5,SFMBT1,CTSA,FOXA1,XDH |
| 2.544e-08 | -17.49 | GNF2_H2AFX | MSigDB lists | GNF2_H2AFX | 31 | 18 | 17758 | 2588 |
ZWINT,DLGAP5,FOXM1,ASPM,CDC20,PTTG1,CDCA8,WHSC1,NUSAP1,CCNF,CDK1,CCNA2,PCNA,PRC1,AURKA,CENPE,CCNB2,SMC4 |
| 2.544e-08 | -17.49 | haematopoietic_and_lymphoid_tissue | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue | 15119 | 2288 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,KDELR3,TFAP2C,PNKD,ABR,LCP1,MPRIP,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,MGST2,KIAA1147,RBM23,MUC16,ZNF365,MYT1,SNX8,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,DNAJB14,TANC1,ZNF618,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,MGAT4A,TUBGCP6,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,FBXO44,ACOT7,TLL2,BCAM,TNK1,KIAA1462,EPAS1,ARFGEF1,PHOSPHO1,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,NCKAP1,RSAD1,B4GALNT1,TNS3,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,ALDH7A1,FAM134C,ATP2B1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TXNDC9,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,FGF19,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,FARP2,PDGFC,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CENPA,ASXL1,ITCH,RGAG1,MAN2A2,HPSE,KCNK1,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,TLE1,SPTBN5,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,EIF5A2,PLEKHA7,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,KIAA0895,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,NF2,UGP2,DGKA,CCDC68,ERBB2,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,XKR8,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,OPN3,CTPS1,PIKFYVE,EEF1D,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,KIAA1841,ZNF84,MMD,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,S100A11,TMEM217,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,SLC16A14,ARL4C,GPR180,APOBEC3H,PNPLA5,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,EBF4,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,FAM219A,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,SNX9,CARD10,CMTM6,LTBP3,NPM2,CDKN2C,NAPG,MUC4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,PRKAR2B,RNF19B,GINS4,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,IL1R1,FNTA,APMAP,S100A5,CLMN,CBX5,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,LRP11,RASGEF1A,SNX10,TMCC2,MX1,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,RGPD5,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,OSR1,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,HJURP,DNAJB2,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FA2H,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,ESPN,NOTCH3,LMAN1,ERLEC1,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,LBR,AIP,PARM1,VPS26A,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,CDK16,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,SYK,LRRC24,P2RX4,HES1,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SPATA20,KCNJ12,LPGAT1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,CAPN12,GPR107,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,FBXO9,YES1,GRTP1,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,MELK,UGT8,COMMD5,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CTTN,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,CARD8,ADRBK1,TAF1B,LLGL2,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,ARHGAP42,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,ZIC5,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,ARPC2,SERPINB1,RPS6KA3,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,CNTRL,DDHD2,DUSP10,TNFRSF18,TLN2,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,MAPK8IP1,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,FYN,PPP2R5A,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,FAM111A,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,AMMECR1,SERPINB5,CCDC69,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,CASP3,LTBP1,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,PITPNA,KLF7,GAS2L1,SLC25A24,ZSWIM5,IL15,PSME2,SLC2A8,GMPR,MORC4,MICALL2,LRRC45,SETDB2,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,MAP3K6,PEX2,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,HNRNPH2,PRCP,UBE2D2,HOXB13,GEM |
| 2.561e-08 | -17.48 | LANDIS_ERBB2_BREAST_TUMORS_324_UP | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_324_UP | 143 | 47 | 17758 | 2588 |
CMAS,INPPL1,DAP,FXYD3,CD82,FHDC1,ETNK1,CYB561,F11R,ITPR2,NUCB2,PDIA4,IER3,CCND1,EPCAM,WEE1,CTSC,NPNT,KCNN4,LMO4,FUT8,AIM1,PAPSS1,CD9,ACSL4,ERBB3,LMAN1,SLC12A2,TIAM1,SMAGP,WBP5,NR4A1,LITAF,EZR,TFAP2C,CDK1,MAPK8IP1,IRX3,GALNT3,SHROOM3,DCK,PTK7,PPP1CB,CTNND1,STK39,FAM134B,FGD1 |
| 2.565e-08 | -17.48 | cell-substrate junction | cellular component | GO:0030055 | 399 | 100 | 17570 | 2579 |
LMO7,SORBS1,ADD1,HSPG2,IQGAP1,SDC1,SLC9A3R2,GNB2,SH3KBP1,CD46,ZYX,CDH1,CTNNB1,P4HB,DNM2,IRF2,KIF22,DIXDC1,CTTN,TLN2,FLOT2,CHP1,LAP3,SNTB2,SYNE2,EZR,TNS1,ERBB2IP,ALCAM,DAG1,LCP1,TNS4,MPRIP,JAK1,CORO1C,PTK7,LIMK1,TRIOBP,PPP1CB,SPRY4,ARF6,RPL22,HSPB1,CAPN1,CD99,LASP1,FBLIM1,HSP90B1,MRC2,PACSIN2,MPZL1,PPP1R12A,ITGA6,ARHGEF7,SDC4,FLOT1,PDIA3,KIF23,SORBS3,NCKAP1,ICAM1,ITGA2B,CORO1B,CALR,CAPN2,RAC2,TNS3,FLII,VASP,ITGA3,FLRT3,CD9,EPB41L5,DCAF6,ADAM17,RHOA,CASK,PLAUR,FHL2,YES1,AIF1L,ILK,SNTB1,BCAR1,RHOB,EGFR,ARHGAP24,SCARB2,RPL12,RND3,PVRL2,ITGA7,ITGAV,FHL1,HMGA1,ARPC2,CD81,L1CAM,AFAP1,CSRP2 |
| 2.668e-08 | -17.44 | WANG_SMARCE1_TARGETS_UP | MSigDB lists | WANG_SMARCE1_TARGETS_UP | 270 | 74 | 17758 | 2588 |
MYL9,BCAM,KIAA1462,HOXB7,EPAS1,GALNT12,LMCD1,GATA3,IL13RA1,SIPA1L2,ST5,SRPX,DACT1,SLC44A1,F2R,CPE,SULF2,TIMP2,CD55,ROR1,PTGFRN,ATP10D,COL12A1,DPYSL3,SOCS3,NGFRAP1,SIPA1L1,MYLK,PLXND1,HS3ST3B1,UNC5B,LIFR,ABCA1,IER5L,CTHRC1,FBLIM1,PLSCR4,IGFBP6,ALDH6A1,ATP9A,TGFBR1,TRIB2,TNFRSF19,KCNC4,CD109,ITGB8,FRY,SNX18,FLRT3,FRAS1,CALD1,TOX2,PCYOX1,FAM102A,ACTA2,ATP8B1,WBP5,CASK,FHL2,IFIT3,ANTXR1,TCEAL8,STEAP1,MAP1B,IL1R1,NUCB1,NIPSNAP3A,MATN2,FIBCD1,PGM2L1,HIPK3,CYBRD1,KLF7,TLL2 |
| 2.722e-08 | -17.42 | kidney-carcinoma-papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-papillary_renal_cell_carcinoma | 6650 | 1092 | 17775 | 2585 |
IBTK,AK7,SLC25A13,RET,MCOLN3,TRAPPC8,ISOC2,SNX9,FAM46C,CARD10,LTBP3,ZNF275,GRM5,MUC4,ATP13A3,PPP1CA,RNF26,TIAM1,CPE,MGAT5,CCDC74A,NEK4,KDELR3,PRKAR2B,ABR,PIAS3,ENPP1,CARHSP1,MPRIP,MID1IP1,ATP7B,CELF5,RNASEL,STARD13,ANXA11,NXT2,ITGA6,MTL5,GPSM2,CCDC64B,TTYH3,RABGGTA,FLII,RAC2,ZCCHC17,FRY,MEGF8,RIMS3,FBXO7,MAP3K9,SLAIN2,CADPS2,ALPK1,MAPK7,ZMYM1,MOXD1,MYLIP,ULBP2,DGKG,PPP6R1,PHKG2,HPS3,KIF20B,NPHP3,C11orf45,MAGED2,CACHD1,SLC4A4,APMAP,DGAT2,CLMN,OSCP1,TMEM159,TMEM173,ADAMTS16,DMPK,DOCK9,GRK6,FAM91A1,REPS1,KIAA1147,APPBP2,RBM23,MUC16,ST5,CDH1,SNX10,MYT1,TMEM200B,MX1,COL6A2,ERMP1,RIPK2,AGPS,SEPT6,TANC1,SNX12,EBF2,GIGYF1,SHROOM3,CDK19,WFS1,AXL,PNPLA6,FAM149A,DMWD,MAPK12,HSP90B1,MPZL1,CKAP2,BACE1,TRAF2,BIK,CCM2,SDC4,OSGIN2,PLPPR4,NFAT5,ZFX,SLC25A45,FUT2,KNDC1,TMEM62,FAM102A,ADAMTS2,PIK3R1,MRS2,NUB1,PGBD1,CNTNAP1,RPL12,LDLRAP1,HCP5,PLOD2,RAB11FIP2,ITGAV,OSR1,CD81,ACOT7,TLL2,TMEM131,TNK1,BCAM,KIAA1462,EPAS1,PHOSPHO1,TEX2,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,ENTPD4,RPS6KA2,NUP210,CTNNB1,RABEP2,P4HB,IL6ST,PSMC2,ABCA2,PLK1,KRT80,MARK1,KCNIP3,CELSR2,STAU2,CBX6,CR2,CKAP2L,ARFRP1,EAF2,TRUB1,DZIP1L,TRIM9,HS6ST1,HOXA9,ARRDC1,MYL12B,RMND5A,PRSS8,RUNX2,USH1C,HJURP,LGALS3,PDCL,ADCK5,NCKAP1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,KIF13B,ICAM5,SLC30A6,AHCY,PIM1,FAR2,PCDH1,PLEKHA6,USP31,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,CDK5R1,FOXD2,FA2H,SLC2A6,ZDHHC7,ZDBF2,PLD1,SEMA3A,CDAN1,RAD21,HOXB7,CTDSPL,TP53,RHPN2,BAHD1,PCBP1,SYTL2,WDR44,TACC2,PLK4,GLB1L2,ESPN,NOTCH3,SULF2,CLCN3,ERLEC1,AKT1,ACO1,DAG1,ATP13A2,IDE,PTPRJ,STK38,SYT13,BTBD6,BIN1,CMAS,PINK1,DYRK3,CDH22,CPEB4,CTSB,SCD5,MCTP2,CDCA8,ERCC6L,HMGN3,LBR,IL22RA1,PARM1,DNAJB9,CD109,FOXP2,ALPP,CDK16,TFAP2A,SGK1,HMGCL,SYK,FAM134C,ATP2B1,NFE2L3,P2RX4,FBLN5,PRICKLE1,MAML2,COL7A1,BBS2,DGKE,DDX23,CNOT2,NIPSNAP3A,NEIL3,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,TXN,LGR4,HSPG2,TMEM86B,VANGL1,CUL1,CAMK1D,NANS,PICK1,SLC9A7,PAK6,ANKS6,ZNF823,STIM1,SERINC2,PIK3CA,KCNS3,IRF2,MARCH2,METAP2,ACVR1C,KIF13A,POR,RAB2B,ANKRD10,GDE1,LRIG1,MAPK13,WBSCR27,RECQL,MRC2,PRKAA1,AKAP17A,TNFRSF19,PDXDC1,MESDC2,C9orf69,DOPEY2,BHLHE41,VASN,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,CACNA1D,TRAK2,GFPT1,SPATA20,GCC2,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,CALM1,DCHS1,PYGL,WHSC1,NPC2,ATP8B3,ANTXR1,NFIB,PDE11A,MMP15,SLCO4A1,PLEKHH2,C1orf21,MATN2,PIAS2,FAM83D,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,CDK18,PER3,PLIN3,IFIH1,KIF3C,GPR107,CAPN12,DLGAP5,ST14,CCDC110,CERCAM,RALBP1,BCL2L1,TMEM170B,TMEM19,FLT3,DDR1,ZFYVE9,EPS8L2,CD46,NOV,ACAP2,TRANK1,EPHB4,DOCK4,CLSTN1,PKMYT1,ATP1B1,ITPR3,ATP10D,FZD7,ZMPSTE24,ACAD10,CCDC149,HAGHL,SLC27A3,PRKAR1A,SLC41A1,EPS8,CBLL1,HERC5,FBXO6,DNAH3,FGF19,HLA-A,CKAP5,SLC25A36,RASSF8,TMEM87B,RNF128,ERBB3,CITED2,SLC16A5,MSH6,FARP2,TGIF1,ARHGEF28,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,C2orf69,UBAC1,YES1,ARSK,CRTC2,ACADSB,DGCR2,SEC14L4,FGFR2,ERAP1,FZD5,WDR91,WDR62,ESPL1,MELK,VARS2,MPP5,ERP29,TRIM68,HTR1D,SIPA1L2,CDKL5,ARHGEF37,SIVA1,CEP78,ASH2L,STK35,CYP1B1,TRAPPC13,CENPA,ASXL1,LAP3,RGAG1,TYSND1,HPSE,MADD,TDRD7,SP6,CAPN1,LASP1,ARAP3,ZNF395,PPP1R12A,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,PFKL,FAM20C,OCRL,COL6A1,MTMR10,PRKCI,BRAT1,C10orf54,NPTN,GAD1,SLC12A2,CCDC88A,SNED1,MDFI,PODXL2,PDE5A,KIAA1109,PRRC1,HEATR5A,PDIK1L,RANBP9,INSR,TMEM30A,SPAG7,RAB31,SH3BP4,SHROOM2,JAK3,TOB1,AFAP1,RARG,DRD1,CCNE2,NCKAP5,LZTFL1,HDAC11,PDIA5,COL18A1,IL27RA,MXD1,KCTD9,ZNF687,ZBTB49,ECE1,ETHE1,NFKB2,UPF3A,TMTC2,CASP4,ALDH5A1,STAT6,SPTBN5,ABCA1,TSPAN15,ARHGEF7,SH3D19,SHPRH,TGFBR1,COL4A5,TRIB2,SBF1,NTAN1,RBP7,SYDE2,HDAC9,KIF5B,TAF1B,ADRBK1,LLGL2,BMP7,ARVCF,KANK2,CLIP2,MYO5A,PGM1,PHF20L1,DCAF6,WNT10B,TTC7A,LEMD2,ARHGAP24,ENDOD1,TRIM69,RND3,SPINT2,ARRB1,UACA,ZMIZ1,AHR,ACACB,KLK10,TRIM24,IL15RA,ADD1,MRPS15,AASS,CACNA2D2,SMARCAL1,KIF26A,CA8,PHF1,DAPK2,WEE1,RGS12,ARHGAP42,DNAH6,CYP2S1,TUBG1,PIK3CD,ACOX2,APOBEC3G,ODF2L,SMARCA2,NWD1,TNIP1,SH3BGRL,MTRF1L,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,TRIM47,WDR11,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,RELL1,LSM14B,E2F8,PDPR,TMTC3,SLC36A4,ZNRF3,MERTK,LMNA,ELF3,GNS,DNPEP,CD22,PRICKLE4,FAM13B,NEK2,NCAM1,C9orf72,EPHX1,SLC37A1,SALL4,MYBL2,CALCRL,SPTLC2,RHOB,STK17A,PTPRF,NCOA3,MTFMT,SEMA4D,HTT,SETD3,ITPR1,AURKA,MDH1,ALG2,ARPC2,TRPC3,ZNF502,RPS6KA3,ARHGAP11A,PAPSS2,ACTR8,TESK2,PKP2,PRSS22,PRKACA,APC2,ZNF385B,UHRF1BP1L,SCNN1A,TMEM9,SCN3A,ENPP4,LGALS8,FZD4,SYNE2,PLEKHO1,NUSAP1,RAB38,PEX5,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TAOK2,FARP1,RBM24,PARP14,GMCL1,ANO9,PKN1,ETS1,KCNC4,GSTP1,HOXB2,TIPRL,SRPX2,ICAM1,PDIA4,NEO1,CAPN2,ANK1,ADD3,IRAK1,CTSC,ANKS1B,KCNK5,FDXR,ECI2,TMBIM6,MAPK11,WWP1,ITM2C,TPCN1,CRTAP,AMOTL2,CTNNAL1,RAPGEF2,DBR1,SNTB1,ABLIM2,TXK,BTG1,KIAA0141,ACVRL1,NR1D2,ATXN7L3,ZFP30,ARFGAP3,HMGA1,CENPE,FOXA1,CYBRD1,MYL9,SIGIRR,TRIM2,AGRN,EPHA4,FHDC1,MCCC1,NDC80,HDAC6,LMAN2L,TLN2,MYBL1,NEB,DDX59,CCDC38,ZNF462,EZR,ANLN,ZBTB7B,LHFPL2,CLCN2,VCP,RHEB,IRX3,OPTN,MSL1,TBC1D17,WIPI1,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,PRKAA2,CNTNAP2,DOCK11,DHRS3,C3orf18,PGAP1,SSX2IP,KIAA0895,IGF1R,EXOC8,PLCB2,ALDH3A2,ABCC1,CHSY3,WDR72,TESK1,CORO2A,PCBP3,SPATA13,EIF2AK1,IFIT3,G2E3,MAPKAPK2,DHDH,PRPS2,LTBP2,UPF3B,NF2,XYLT1,DGKA,ZNF28,ERBB2,FAM198B,SLC7A2,CYP26A1,PER2,CDK14,ATP6V0B,EFR3A,PLCG2,GYS1,SCN2A,CTH,TMTC1,MBP,CDC20,DUOX1,DNAJC10,PRRT4,ATP1A1,PTK7,ADAMTS14,ZBTB6,RPL22,NDST3,CMTM4,COL9A3,GOLIM4,TRAPPC10,RUSC2,SELL,JAG2,PPP2R3A,CEP97,SLC35B4,BUB1,FAIM,CAMK2G,IGDCC4,DLGAP1,PSMB4,NR3C1,IFITM3,AMFR,TRIM35,FXR2,AKAP3,BCAR1,BSDC1,MAPK8IP1,SCRN2,FUCA1,FAT4,SERPINA1,NAT1,TMC5,PGRMC1,NETO2,PKD2,TBC1D4,NDFIP1,SAT2,ACVR1,PPP4R4,TTC39B,PPFIBP2,TAP1,PLXNA1,SLC20A1,CTGF,IQCE,RGS3,ZFP36,IL31RA,AOX1,ATRNL1,LAMP2,LOC81691,KIFC2,PBK,CASP9,NBPF3,TNS1,AURKB,GALNT7,SAV1,SLC25A5,ULK2,AHRR,RBM47,GNPTAB,PLK2,NKD1,FAM110C,DHTKD1,UNC5B,TANC2,LZTS1,DDX58,CDK17,INPPL1,MRPL44,HLA-E,C6orf106,NOTCH2,BMP2K,ITGA3,SLC16A6,SORL1,CTSD,TSPAN33,EEF1D,IGSF3,PMPCB,TBC1D8B,MICB,ANO6,PTPRH,AMER1,TMEM133,KCTD20,PKM,FBXO10,FRMD4B,DGKH,GABRD,DCK,NAB2,TCEAL4,FGD6,EFNA1,MAP3K5,NRBP1,FRMPD3,SLC2A4,NLRX1,TRIP10,RPS6KA1,IQGAP1,CD274,AIFM2,FAM46A,CNNM4,DAB2IP,PHKA2,MYO5B,SEC23A,TMEM43,TEP1,COX11,PRKCQ,C15orf39,SP4,ZNF469,NIN,EPHA10,FYN,JAK1,STAT1,KIAA1804,SLC27A1,KLF5,NRG1,MLKL,NR3C2,DENND5B,ANKRD13D,ARHGEF3,SLC16A14,CYB561,GPR180,SEPP1,PNPLA5,SIX4,LGALS3BP,RND1,TMCC3,SNTA1,C16orf59,PTEN,PRC1,SGK3,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,CASK,MPP1,PARP4,LRRC1,GPLD1,MAMDC4,CTNS,ETAA1,SLC25A38,JARID2,EXPH5,CASP3,LTBP1,CAMKK1,HEBP1,KIF2C,TMC1,PTCHD4,SH3KBP1,ABCD4,CHPF,MAGOHB,ARHGEF10L,GRHL1,DLG1,ANKRD12,AKR1B1,SUN3,RP2,MYH14,RASGRP1,OLFML2A,TDP1,TRIM8,SYNE3,ROR1,ADRBK2,STK17B,ARHGEF19,NEIL1,TRIM45,IARS2,CCDC74B,RAP1GAP,APBA2,PEX6,SAMD9,PHLPP1,LRRN2,KCNN4,FNIP1,RFX5,ACAD8,ALS2CL,OXR1,AMDHD1,EGFR,GLCE,XKRX,BCAR3,TSC1,SLC6A6,UTP14C,NFKBIA,ALPK3,EGFL7,KIF12,FBXW5,PROM2,ZSWIM5,SPC25,PSME2,SLC2A8,ABCG4,GMPR,MORC4,ZMYND10,MICALL2,SLC25A48,SS18,FRYL,F2R,PDIA6,SCYL3,HSPA2,FRS3,MAP3K3,GCA,SLC39A8,DOCK5,MAP3K6,BHLHB9,OVOL1,PLXND1,AKNA,LIFR,CBX4,ANXA3,JKAMP,LRP4,FAM134A,NOTUM,IRF2BPL,MDM1,GALNS,KIAA0319,TRIM3,SUN2,ADAM17,ASPM,GCLC,MBNL3,MAP1B,HLA-B,C2orf70,PRCP,GEM,LRRC57,SNPH |
| 2.722e-08 | -17.42 | papillary_renal_cell_carcinoma | COSMIC cancer mutations | papillary_renal_cell_carcinoma | 6650 | 1092 | 17775 | 2585 |
IBTK,AK7,SLC25A13,RET,MCOLN3,TRAPPC8,ISOC2,SNX9,FAM46C,CARD10,LTBP3,ZNF275,GRM5,MUC4,ATP13A3,PPP1CA,RNF26,TIAM1,CPE,MGAT5,CCDC74A,NEK4,KDELR3,PRKAR2B,ABR,PIAS3,ENPP1,CARHSP1,MPRIP,MID1IP1,ATP7B,CELF5,RNASEL,STARD13,ANXA11,NXT2,ITGA6,MTL5,GPSM2,CCDC64B,TTYH3,RABGGTA,FLII,RAC2,ZCCHC17,FRY,MEGF8,RIMS3,FBXO7,MAP3K9,SLAIN2,CADPS2,ALPK1,MAPK7,ZMYM1,MOXD1,MYLIP,ULBP2,DGKG,PPP6R1,PHKG2,HPS3,KIF20B,NPHP3,C11orf45,MAGED2,CACHD1,SLC4A4,APMAP,DGAT2,CLMN,OSCP1,TMEM159,TMEM173,ADAMTS16,DMPK,DOCK9,GRK6,FAM91A1,REPS1,KIAA1147,APPBP2,RBM23,MUC16,ST5,CDH1,SNX10,MYT1,TMEM200B,MX1,COL6A2,ERMP1,RIPK2,AGPS,SEPT6,TANC1,SNX12,EBF2,GIGYF1,SHROOM3,CDK19,WFS1,AXL,PNPLA6,FAM149A,DMWD,MAPK12,HSP90B1,MPZL1,CKAP2,BACE1,TRAF2,BIK,CCM2,SDC4,OSGIN2,PLPPR4,NFAT5,ZFX,SLC25A45,FUT2,KNDC1,TMEM62,FAM102A,ADAMTS2,PIK3R1,MRS2,NUB1,PGBD1,CNTNAP1,RPL12,LDLRAP1,HCP5,PLOD2,RAB11FIP2,ITGAV,OSR1,CD81,ACOT7,TLL2,TMEM131,TNK1,BCAM,KIAA1462,EPAS1,PHOSPHO1,TEX2,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,ENTPD4,RPS6KA2,NUP210,CTNNB1,RABEP2,P4HB,IL6ST,PSMC2,ABCA2,PLK1,KRT80,MARK1,KCNIP3,CELSR2,STAU2,CBX6,CR2,CKAP2L,ARFRP1,EAF2,TRUB1,DZIP1L,TRIM9,HS6ST1,HOXA9,ARRDC1,MYL12B,RMND5A,PRSS8,RUNX2,USH1C,HJURP,LGALS3,PDCL,ADCK5,NCKAP1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,KIF13B,ICAM5,SLC30A6,AHCY,PIM1,FAR2,PCDH1,PLEKHA6,USP31,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,CDK5R1,FOXD2,FA2H,SLC2A6,ZDHHC7,ZDBF2,PLD1,SEMA3A,CDAN1,RAD21,HOXB7,CTDSPL,TP53,RHPN2,BAHD1,PCBP1,SYTL2,WDR44,TACC2,PLK4,GLB1L2,ESPN,NOTCH3,SULF2,CLCN3,ERLEC1,AKT1,ACO1,DAG1,ATP13A2,IDE,PTPRJ,STK38,SYT13,BTBD6,BIN1,CMAS,PINK1,DYRK3,CDH22,CPEB4,CTSB,SCD5,MCTP2,CDCA8,ERCC6L,HMGN3,LBR,IL22RA1,PARM1,DNAJB9,CD109,FOXP2,ALPP,CDK16,TFAP2A,SGK1,HMGCL,SYK,FAM134C,ATP2B1,NFE2L3,P2RX4,FBLN5,PRICKLE1,MAML2,COL7A1,BBS2,DGKE,DDX23,CNOT2,NIPSNAP3A,NEIL3,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,TXN,LGR4,HSPG2,TMEM86B,VANGL1,CUL1,CAMK1D,NANS,PICK1,SLC9A7,PAK6,ANKS6,ZNF823,STIM1,SERINC2,PIK3CA,KCNS3,IRF2,MARCH2,METAP2,ACVR1C,KIF13A,POR,RAB2B,ANKRD10,GDE1,LRIG1,MAPK13,WBSCR27,RECQL,MRC2,PRKAA1,AKAP17A,TNFRSF19,PDXDC1,MESDC2,C9orf69,DOPEY2,BHLHE41,VASN,AIM1,DAPK1,TMEM51,PRKG1,ADCK2,TPST1,CACNA1D,TRAK2,GFPT1,SPATA20,GCC2,PRODH,KCNJ12,KLK5,PRSS23,ADCK3,CALM1,DCHS1,PYGL,WHSC1,NPC2,ATP8B3,ANTXR1,NFIB,PDE11A,MMP15,SLCO4A1,PLEKHH2,C1orf21,MATN2,PIAS2,FAM83D,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,CDK18,PER3,PLIN3,IFIH1,KIF3C,GPR107,CAPN12,DLGAP5,ST14,CCDC110,CERCAM,RALBP1,BCL2L1,TMEM170B,TMEM19,FLT3,DDR1,ZFYVE9,EPS8L2,CD46,NOV,ACAP2,TRANK1,EPHB4,DOCK4,CLSTN1,PKMYT1,ATP1B1,ITPR3,ATP10D,FZD7,ZMPSTE24,ACAD10,CCDC149,HAGHL,SLC27A3,PRKAR1A,SLC41A1,EPS8,CBLL1,HERC5,FBXO6,DNAH3,FGF19,HLA-A,CKAP5,SLC25A36,RASSF8,TMEM87B,RNF128,ERBB3,CITED2,SLC16A5,MSH6,FARP2,TGIF1,ARHGEF28,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,C2orf69,UBAC1,YES1,ARSK,CRTC2,ACADSB,DGCR2,SEC14L4,FGFR2,ERAP1,FZD5,WDR91,WDR62,ESPL1,MELK,VARS2,MPP5,ERP29,TRIM68,HTR1D,SIPA1L2,CDKL5,ARHGEF37,SIVA1,CEP78,ASH2L,STK35,CYP1B1,TRAPPC13,CENPA,ASXL1,LAP3,RGAG1,TYSND1,HPSE,MADD,TDRD7,SP6,CAPN1,LASP1,ARAP3,ZNF395,PPP1R12A,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,PFKL,FAM20C,OCRL,COL6A1,MTMR10,PRKCI,BRAT1,C10orf54,NPTN,GAD1,SLC12A2,CCDC88A,SNED1,MDFI,PODXL2,PDE5A,KIAA1109,PRRC1,HEATR5A,PDIK1L,RANBP9,INSR,TMEM30A,SPAG7,RAB31,SH3BP4,SHROOM2,JAK3,TOB1,AFAP1,RARG,DRD1,CCNE2,NCKAP5,LZTFL1,HDAC11,PDIA5,COL18A1,IL27RA,MXD1,KCTD9,ZNF687,ZBTB49,ECE1,ETHE1,NFKB2,UPF3A,TMTC2,CASP4,ALDH5A1,STAT6,SPTBN5,ABCA1,TSPAN15,ARHGEF7,SH3D19,SHPRH,TGFBR1,COL4A5,TRIB2,SBF1,NTAN1,RBP7,SYDE2,HDAC9,KIF5B,TAF1B,ADRBK1,LLGL2,BMP7,ARVCF,KANK2,CLIP2,MYO5A,PGM1,PHF20L1,DCAF6,WNT10B,TTC7A,LEMD2,ARHGAP24,ENDOD1,TRIM69,RND3,SPINT2,ARRB1,UACA,ZMIZ1,AHR,ACACB,KLK10,TRIM24,IL15RA,ADD1,MRPS15,AASS,CACNA2D2,SMARCAL1,KIF26A,CA8,PHF1,DAPK2,WEE1,RGS12,ARHGAP42,DNAH6,CYP2S1,TUBG1,PIK3CD,ACOX2,APOBEC3G,ODF2L,SMARCA2,NWD1,TNIP1,SH3BGRL,MTRF1L,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,TRIM47,WDR11,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,RELL1,LSM14B,E2F8,PDPR,TMTC3,SLC36A4,ZNRF3,MERTK,LMNA,ELF3,GNS,DNPEP,CD22,PRICKLE4,FAM13B,NEK2,NCAM1,C9orf72,EPHX1,SLC37A1,SALL4,MYBL2,CALCRL,SPTLC2,RHOB,STK17A,PTPRF,NCOA3,MTFMT,SEMA4D,HTT,SETD3,ITPR1,AURKA,MDH1,ALG2,ARPC2,TRPC3,ZNF502,RPS6KA3,ARHGAP11A,PAPSS2,ACTR8,TESK2,PKP2,PRSS22,PRKACA,APC2,ZNF385B,UHRF1BP1L,SCNN1A,TMEM9,SCN3A,ENPP4,LGALS8,FZD4,SYNE2,PLEKHO1,NUSAP1,RAB38,PEX5,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,RGS14,TTC8,TAOK2,FARP1,RBM24,PARP14,GMCL1,ANO9,PKN1,ETS1,KCNC4,GSTP1,HOXB2,TIPRL,SRPX2,ICAM1,PDIA4,NEO1,CAPN2,ANK1,ADD3,IRAK1,CTSC,ANKS1B,KCNK5,FDXR,ECI2,TMBIM6,MAPK11,WWP1,ITM2C,TPCN1,CRTAP,AMOTL2,CTNNAL1,RAPGEF2,DBR1,SNTB1,ABLIM2,TXK,BTG1,KIAA0141,ACVRL1,NR1D2,ATXN7L3,ZFP30,ARFGAP3,HMGA1,CENPE,FOXA1,CYBRD1,MYL9,SIGIRR,TRIM2,AGRN,EPHA4,FHDC1,MCCC1,NDC80,HDAC6,LMAN2L,TLN2,MYBL1,NEB,DDX59,CCDC38,ZNF462,EZR,ANLN,ZBTB7B,LHFPL2,CLCN2,VCP,RHEB,IRX3,OPTN,MSL1,TBC1D17,WIPI1,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,EPB41L4A,PRKAA2,CNTNAP2,DOCK11,DHRS3,C3orf18,PGAP1,SSX2IP,KIAA0895,IGF1R,EXOC8,PLCB2,ALDH3A2,ABCC1,CHSY3,WDR72,TESK1,CORO2A,PCBP3,SPATA13,EIF2AK1,IFIT3,G2E3,MAPKAPK2,DHDH,PRPS2,LTBP2,UPF3B,NF2,XYLT1,DGKA,ZNF28,ERBB2,FAM198B,SLC7A2,CYP26A1,PER2,CDK14,ATP6V0B,EFR3A,PLCG2,GYS1,SCN2A,CTH,TMTC1,MBP,CDC20,DUOX1,DNAJC10,PRRT4,ATP1A1,PTK7,ADAMTS14,ZBTB6,RPL22,NDST3,CMTM4,COL9A3,GOLIM4,TRAPPC10,RUSC2,SELL,JAG2,PPP2R3A,CEP97,SLC35B4,BUB1,FAIM,CAMK2G,IGDCC4,DLGAP1,PSMB4,NR3C1,IFITM3,AMFR,TRIM35,FXR2,AKAP3,BCAR1,BSDC1,MAPK8IP1,SCRN2,FUCA1,FAT4,SERPINA1,NAT1,TMC5,PGRMC1,NETO2,PKD2,TBC1D4,NDFIP1,SAT2,ACVR1,PPP4R4,TTC39B,PPFIBP2,TAP1,PLXNA1,SLC20A1,CTGF,IQCE,RGS3,ZFP36,IL31RA,AOX1,ATRNL1,LAMP2,LOC81691,KIFC2,PBK,CASP9,NBPF3,TNS1,AURKB,GALNT7,SAV1,SLC25A5,ULK2,AHRR,RBM47,GNPTAB,PLK2,NKD1,FAM110C,DHTKD1,UNC5B,TANC2,LZTS1,DDX58,CDK17,INPPL1,MRPL44,HLA-E,C6orf106,NOTCH2,BMP2K,ITGA3,SLC16A6,SORL1,CTSD,TSPAN33,EEF1D,IGSF3,PMPCB,TBC1D8B,MICB,ANO6,PTPRH,AMER1,TMEM133,KCTD20,PKM,FBXO10,FRMD4B,DGKH,GABRD,DCK,NAB2,TCEAL4,FGD6,EFNA1,MAP3K5,NRBP1,FRMPD3,SLC2A4,NLRX1,TRIP10,RPS6KA1,IQGAP1,CD274,AIFM2,FAM46A,CNNM4,DAB2IP,PHKA2,MYO5B,SEC23A,TMEM43,TEP1,COX11,PRKCQ,C15orf39,SP4,ZNF469,NIN,EPHA10,FYN,JAK1,STAT1,KIAA1804,SLC27A1,KLF5,NRG1,MLKL,NR3C2,DENND5B,ANKRD13D,ARHGEF3,SLC16A14,CYB561,GPR180,SEPP1,PNPLA5,SIX4,LGALS3BP,RND1,TMCC3,SNTA1,C16orf59,PTEN,PRC1,SGK3,SLC44A2,MAP3K7,GFI1,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,CASK,MPP1,PARP4,LRRC1,GPLD1,MAMDC4,CTNS,ETAA1,SLC25A38,JARID2,EXPH5,CASP3,LTBP1,CAMKK1,HEBP1,KIF2C,TMC1,PTCHD4,SH3KBP1,ABCD4,CHPF,MAGOHB,ARHGEF10L,GRHL1,DLG1,ANKRD12,AKR1B1,SUN3,RP2,MYH14,RASGRP1,OLFML2A,TDP1,TRIM8,SYNE3,ROR1,ADRBK2,STK17B,ARHGEF19,NEIL1,TRIM45,IARS2,CCDC74B,RAP1GAP,APBA2,PEX6,SAMD9,PHLPP1,LRRN2,KCNN4,FNIP1,RFX5,ACAD8,ALS2CL,OXR1,AMDHD1,EGFR,GLCE,XKRX,BCAR3,TSC1,SLC6A6,UTP14C,NFKBIA,ALPK3,EGFL7,KIF12,FBXW5,PROM2,ZSWIM5,SPC25,PSME2,SLC2A8,ABCG4,GMPR,MORC4,ZMYND10,MICALL2,SLC25A48,SS18,FRYL,F2R,PDIA6,SCYL3,HSPA2,FRS3,MAP3K3,GCA,SLC39A8,DOCK5,MAP3K6,BHLHB9,OVOL1,PLXND1,AKNA,LIFR,CBX4,ANXA3,JKAMP,LRP4,FAM134A,NOTUM,IRF2BPL,MDM1,GALNS,KIAA0319,TRIM3,SUN2,ADAM17,ASPM,GCLC,MBNL3,MAP1B,HLA-B,C2orf70,PRCP,GEM,LRRC57,SNPH |
| 2.741e-08 | -17.41 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | 7542 | 1224 | 17775 | 2585 |
HECA,FAM160B1,IBTK,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,SNX9,FAM46C,SPSB1,CARD10,CMTM6,LTBP3,GRM5,NPM2,PHYHIP,PAQR5,ATP13A3,DNM2,WBP4,TIAM1,IL10RB,CPE,TIPARP,MGAT5,UXT,PRKAR2B,ABR,LCP1,ENPP1,BOLA3,C17orf51,CELF5,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,STARD13,SCN5A,GGA1,TTYH3,ATG4A,MARCH8,FLII,RAC2,FRY,PAIP2B,MEGF8,RIMS3,FBXO7,FBXL14,PCYOX1,MAP3K9,SLAIN2,CADPS2,USP38,ALPK1,CNGA1,ZMYM1,MOXD1,MYLIP,DGKG,NUP85,TTLL1,MCCC2,HPS3,PQLC3,FHL2,NPHP3,PCTP,SFXN5,GNA11,IL1R1,CACHD1,SLC4A4,DGAT2,CLMN,OSCP1,CBX5,ADAMTS16,DOCK9,WDR63,RHBDL3,APOO,FAM91A1,REPS1,APPBP2,RBM23,MUC16,CDH1,XYLT2,RASGEF1A,DLG3,TMCC2,MX1,SNX8,PFKFB2,AGPS,PTPN9,SEPT6,VPS4B,TANC1,ZNF618,EBF2,PDLIM3,CCNB3,SHROOM3,CDK19,WFS1,PNPLA6,FAM149A,DMWD,HSP90B1,FAM189A2,TRAF2,HABP4,FLOT1,BTN3A1,CTSZ,IFT27,SLC25A43,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,MGAT4A,TUBGCP6,KLC3,FAM102A,CASD1,PVRL4,ADAMTS2,PLSCR1,PIK3R1,MRS2,CXorf57,UBE2A,AK4,PGBD1,PROM1,LDLRAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,PPM1H,ITGAV,ACOT7,TLL2,TMEM131,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,DNAJB11,TEX2,GALM,ITPR2,SPTB,PLS3,SUSD2,CPNE2,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,P4HB,NPNT,IL6ST,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,THRB,MARK1,KCNIP3,CELSR2,CR2,CKAP2L,SESN1,PLEKHG6,TMEM164,HS6ST1,TRAM2,KLF12,KPNA2,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,PARP12,HJURP,LGALS3,RASA2,SORBS3,ADCK5,NCKAP1,FBLN1,ANO1,MYO5C,B4GALNT1,TNS3,FRAS1,FCHO1,SLC30A6,AHCY,FAR2,WNT3A,NTN1,PCDH1,PLEKHA6,USP31,MGAT4B,SCRIB,ZSCAN12,BCL2L13,C18orf8,RASGRP2,FA2H,PHLPP2,P4HA3,NLRC5,ZDBF2,PLD1,SEMA3A,USP43,RAD21,CTDSPL,TMX4,TP53,RHPN2,P2RX7,STIL,SYTL2,PDGFA,TTC21B,WDR44,TACC2,PPME1,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,SULF2,CLCN3,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,PTGS2,IDE,PTPRJ,PAFAH1B3,ABHD12,MAOA,XRCC3,EFNA5,SYT13,ARHGAP4,FAM134B,BIN1,PINK1,DYRK3,CDH22,CPEB4,KLHL13,SCD5,GNAL,MCTP2,HAL,HMGN3,AIP,PARM1,NRP2,DNAJB9,SH2D4A,ZDHHC21,CD109,LYPD6,GTF2F2,IL17RA,SGK1,TSPAN13,CPLX1,HMGCL,ATP2B1,GCNT1,P2RX4,FBLN5,RHOA,PLAUR,STMN3,MAML2,COL7A1,RNPEP,BBS2,CNOT2,DDAH1,FGF18,HIPK3,ARHGEF4,GOLGB1,FAM171B,LAMP1,SLC35D2,LGR4,HSPG2,SSH1,TSC22D3,C1orf198,CUL1,PDGFRL,SEPT4,PJA2,SLC9A7,PAK6,ANKS6,STIM1,OSBPL3,FOSB,POLL,PIK3CA,SNX16,IRF2,ACVR1C,CDYL,KIF13A,LDB2,POR,RAB2B,ANKRD10,GDE1,PPP2R4,LRIG1,PRDM5,MAPK13,NFKBIZ,SERPINI1,F2RL1,SLC31A2,CCDC97,FGD1,SEMA6B,RECQL,MRC2,SCOC,TBC1D1,PRKAA1,APBA1,TNFRSF19,PDXDC1,SH3RF2,DOPEY2,RALGPS2,ZNRF2,MSH2,DAPK1,TMEM51,PRKG1,CACNA1D,DLX4,TRAK2,SPATA20,GCC2,CEP89,LPGAT1,CALM1,PYGL,WHSC1,ATP8B3,ANTXR1,NFIB,PDE11A,NT5C2,PLEKHH2,TJP3,PELI2,ZDHHC20,C1orf21,MPP2,APPL2,ARAP1,AGBL5,CABIN1,KLK7,PER3,PLIN3,HOOK1,IFIH1,SPRED1,KIF3C,FOXO6,TCF25,TCTN2,GPR107,ST14,NDRG1,RALBP1,DDIT4L,ATP2C2,BCL2L1,TMEM170B,FLT3,DDR1,ART5,CYP39A1,ZFYVE9,EPM2A,CD46,ACAP2,RNASEH2A,PDE4D,OSBPL7,FLOT2,SULT2B1,MED30,DOCK4,COG2,PANK1,CLSTN1,UTRN,TMEM144,PKMYT1,CBL,ITPR3,ALCAM,ATP10D,TSPAN18,ZNF704,COBL,CBX7,MAMDC2,PRKAR1A,IGFBP6,SLC41A1,HERC5,EFHD2,PBX3,NES,PLD2,DNAH3,EFNB1,HLA-A,WWP2,E2F7,RNF128,DRAM1,CD9,TTPA,MSH6,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,PAPD7,ZKSCAN2,FBXO9,DIAPH2,GRTP1,FOS,KIF11,CDK5RAP1,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR62,ESPL1,CXorf56,MELK,UGT8,VARS2,MPP5,ECI1,ADPRHL1,ZFYVE16,SIPA1L2,CDKL5,CASC4,ARHGEF37,SIVA1,ANKFN1,ASH2L,CTTN,MYRIP,LAMP3,ASXL1,ACBD3,ITCH,ARHGDIB,MAN2A2,HPSE,KCNK1,SH3GLB2,GLA,NR2C2,CD99,LASP1,ARAP3,PPP1R12A,PYROXD2,CALM3,FAM81A,DUSP5,SPP1,TYW3,PFKL,FAM20C,OCRL,PRKCI,SRP54,LIMCH1,BRAT1,C10orf54,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNED1,PDE5A,KIAA1109,MFSD7,RANBP9,RHPN1,INSR,UAP1,TMEM30A,SPAG7,DCUN1D1,RAB31,NXPH4,SHROOM2,COL16A1,APOL2,SNX30,LMO7,NCKAP5,PAX6,SORBS1,HDAC11,SOD2,PDIA5,COL18A1,MRAS,PHLDA1,KIF14,REEP1,DIXDC1,EPB41L4B,ETHE1,UPF3A,EBAG9,SOAT1,MRPS35,TMTC2,PDHX,CASP4,ARHGAP35,HSF4,ALDH5A1,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,GLIS3,FBLIM1,ARHGEF11,TSPAN15,SH3D19,TGFBR1,INTS8,RBP7,XPR1,HDAC9,TMEM63A,TOP2A,TAF1B,ADRBK1,BMP7,TOX2,RRBP1,ZDHHC13,H2AFY,CLIP2,C12orf75,SLC35A1,RPGR,MYO5A,RBMS2,PGM1,SYBU,RC3H2,TTC7A,RUNX3,LEPR,FOXL1,LEMD2,ENDOD1,SWAP70,CASP7,TRIM69,SPINT2,CSGALNACT1,ARRB1,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,DOC2A,ACACB,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,XIAP,CACNA2D2,DHX8,NRG2,CA8,KIF26A,BARD1,EPDR1,DAPK2,TP73,ZYX,TGFBR3,RGS12,ARHGAP42,KIAA1107,DNAH6,CABP1,PPP1R16A,KLF3,ALDH1A3,TINAGL1,PIK3CD,ODF2L,ERAP2,SMARCA2,SPEF2,SH3BGRL,MTRF1L,LOXL2,F12,PPP1R14C,MYOM1,CYP4F3,COL12A1,WDR11,DNM1L,LIMK1,MYLK,RELL1,GAB1,FAM169A,SLC36A4,LMNA,RAVER2,DNPEP,WDFY1,FAM189A1,PRICKLE4,FAM13B,STT3B,NCAM1,C9orf72,SLC37A1,SALL4,STAT4,CALCRL,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NAAA,HTT,SETD3,ITPR1,DYSF,AURKA,OSMR,TRPC3,SERPINB1,RPS6KA3,XDH,EGLN1,MTM1,GRHL2,PAPSS2,RGS20,WDTC1,PKP2,TESK2,IL13RA1,PRKACA,TNFSF9,ZNF385B,UHRF1BP1L,CDS1,SCNN1A,RTKN2,ACSL4,RAB27B,SCN3A,RNF169,ENPP4,SSH3,LGALS8,FZD4,SYNE2,NUSAP1,CDCA2,RAB38,TTC12,WWTR1,SIPA1L1,INPP4B,PLEKHG1,PDXK,RGS14,ARNT,TTC8,FARP1,PARP14,GMCL1,ANO9,NUCB2,GSTP1,ETS1,KCNC4,SRPX2,ICAM1,PDIA4,NEO1,CAPN2,SLC27A6,ARSG,CTSC,ANKS1B,KCNK5,CALD1,FDXR,MAPK11,WWP1,AK3,HCN3,AMOTL2,FMN1,CTNNAL1,RAPGEF2,GRIN1,PLEKHA7,BLVRA,SNTB1,CRISPLD2,ABLIM2,TXK,DCAF10,GALNT3,KIAA0141,ACVRL1,NR1D2,CCDC6,CENPE,NUP37,USF2,CYBRD1,DCBLD1,AGRN,GNPDA1,CUL4B,EPHA4,FHDC1,MCCC1,SDC1,PIGL,SHC3,DDHD2,RGS5,TLN2,ANO4,MYBL1,NEB,DDX59,CCDC38,ZNF462,CD55,MCTP1,ERP44,ANLN,PRKRA,IDH1,LHFPL2,CLCN2,VCP,RHEB,OPTN,MAP2,P4HA2,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,GLCCI1,BMF,UBASH3B,CNTNAP2,B4GALT4,DOCK11,PGAP1,SSX2IP,RB1,DAZAP1,KIAA0895,IGF1R,MDFIC,PSMA5,ABCC1,CHSY3,WDR72,SPATA13,TCF7,IFIT3,UNC45B,ANKRD29,ZDHHC3,G2E3,MAPKAPK2,DHDH,EPN3,PRPS2,LTBP2,ATP1B3,NIPA1,FAM45A,NF2,XYLT1,DGKA,ERBB2,CCDC68,SLC7A2,CDK14,SRPX,EFR3A,GYS1,SCN2A,FAR1,CPD,SIRT1,TMTC1,MBP,DUOX1,ATP1A1,C19orf66,PSMD3,PTK7,ADAMTS14,AIFM3,NDST3,ZC3HC1,MAN2B2,COL9A3,GOLIM4,TM2D2,PACSIN2,TRAPPC10,MACC1,DAP,BLVRB,GABRG2,DSE,SIRPA,SLC9A2,MAGEE1,ABCD1,BUB1,KLF9,FAH,IGDCC4,DLGAP1,HMMR,CRB3,NR3C1,AMFR,FXR2,FNDC3A,PRDX4,CD83,BANK1,CDKN2AIPNL,FAT4,TWSG1,TMC5,CDCA7L,NETO2,FAM117A,CLIP4,PPP2R3C,PKD2,TBC1D4,SUN1,GAA,PPP4R4,FAM129B,ATP8A1,PPFIBP2,TAP1,PLXNA1,SLC20A1,CHST2,SESN3,RGS3,IL31RA,AOX1,ATRNL1,MTMR11,TMEM68,SNTB2,HSPA12A,CASP9,MGAM,TNS1,GALNT7,SLC17A5,CCNF,SAV1,SPNS3,SGPP1,AHRR,KDSR,GNPTAB,NKD1,UNC5B,TANC2,TRAF5,RTN3,DLAT,DDX58,FRMD4A,CALB2,SLC25A27,C6orf106,KIF23,NOTCH2,SLC1A3,PIK3AP1,RUNDC3B,SORL1,CD70,PIKFYVE,CTSD,TSPAN33,RIMS2,FAM69A,DNAI1,PMPCB,MMD,TBC1D8B,ANO6,PTPRH,KCTD20,KDM3A,FBXO10,STX3,RASA1,FRMD4B,DGKH,GABRD,SERTAD2,PRKAG2,FGD6,PCDH19,MAP3K5,NRBP1,PKD1L2,FRMPD3,PLA2G4A,SLC2A4,CEP70,S100A11,CAST,SUZ12,IQGAP1,EGR3,MNS1,TMPRSS4,SLC25A35,ZNF75D,IFIT1,PHKA2,LGMN,TBC1D10B,MYO5B,SEC23A,CDKN2AIP,LYRM1,TEP1,COX11,PRKCQ,BCL7B,H2AFV,SP4,CMTM7,PRDM11,NIN,OSBPL2,EPHA10,FYN,PPP2R5A,ACYP1,KIAA1804,STAT1,SLC27A1,KLF5,NRG1,ZC3H12B,HS3ST3B1,MLKL,NR3C2,DENND5B,MRPS9,OTUD5,WASF3,ATP9A,CCNJL,GPR180,TEAD3,LGALS3BP,RND1,TMCC3,SNTA1,AKIRIN1,C16orf59,PTEN,PRC1,MAP3K7,CNPY3,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,PCCB,ARAP2,CASK,MPP1,PARP4,LRRC1,RGS9,MAMDC4,RCBTB2,SLC25A40,AMMECR1,SERPINB5,CSTF2,ETAA1,SLC25A38,ARSB,CPEB2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,TMEM184B,CPT2,FLYWCH2,HEBP1,EPHX4,TAF6L,DNER,KREMEN1,TMC1,SH3KBP1,PTCHD4,CHPF,NKAIN3,ARHGEF10L,LRRC6,IMPAD1,TSPAN6,DPYSL2,PHTF1,DLG1,ANKRD12,POF1B,KIF22,SUN3,RAB20,NFU1,MYH14,ARNT2,SLC39A10,TECR,PTPRE,RASGRP1,OLFML2A,ATL1,TDP1,TRIM8,RNF165,ROR1,PTGFRN,ADRBK2,TCN2,EDNRA,SEC14L2,FASTKD1,IARS2,ADIPOR1,APBA2,RAP1GAP,CPPED1,STARD3NL,LRRFIP2,ELOVL7,SAMD9,PHLPP1,LRRN2,FNIP1,KNTC1,ACAD8,NCEH1,ALS2CL,PARD3B,GYLTL1B,BTN3A2,FBXO8,EGFR,MUM1L1,GNAS,XKRX,FECH,BCAR3,SLC6A6,RHOBTB2,ALPK3,PITPNA,PROM2,ZSWIM5,FAM92A1,ABCG4,SLC25A48,SS18,SETDB2,FRYL,SMO,GOT1,RPN2,APIP,LOXL1,PDIA6,SCYL3,FRS3,MAP3K3,GCA,TAF5,SLC39A8,OSTM1,DOCK5,KCTD2,BFSP1,CANT1,VSIG10,LIFR,ANXA3,CDS2,SORT1,POC1B,ARMC7,LRP4,MIER3,AES,NOTUM,TRMT2B,FAM167A,SNX13,MDM1,ADORA1,GALNS,BRD7,IQGAP3,SUN2,ASPM,GCLC,PHLDB3,MBNL3,OGDHL,SPAG1,MAP1B,KLHL2,GLB1,SOX8,ATP6V1C1 |
| 2.744e-08 | -17.41 | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN | 198 | 59 | 17758 | 2588 |
IGFBP6,LGALS3,CD63,GALNT12,CTSB,HEXB,PPFIBP2,ASAH1,KCTD12,RASGRP3,IL18,FTH1,CTSZ,TEX2,SLC1A3,PHF1,SIRPA,TMEM63A,SGPL1,ZFYVE16,TYMP,CA2,CTSC,AIM1,CD9,TMEM51,RAB20,CRY2,PTPRE,ITM2C,SYK,GM2A,CCDC88A,CKAP4,CYP1B1,VPS11,PDGFC,TIMP2,ALDH2,MMD,PLAUR,SAT1,DCHS1,PYGL,SLC11A2,TCF7,ATP1B1,LHFPL2,FOS,KDSR,MSL1,RBM47,SLC2A6,PLA2G15,ARAP1,ARRB1,SLC27A3,MAFF,RRAGD |
| 2.854e-08 | -17.37 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | 175 | 54 | 17758 | 2588 |
LMO7,NCKAP5,ARHGEF3,NUAK1,CAST,EPHA4,IL18,SLC1A3,SLC7A2,SEPP1,PDGFB,ADAMTSL4,FBLN1,CARD10,LGALS3BP,SDF4,SNTA1,PLCG2,COL6A1,DRAM1,SCARA3,S100A13,GM2A,SCN3A,ADAMTS2,COL6A2,PLEKHA6,CDA,PRICKLE1,ZFAND5,PCTP,EGFR,EPN3,RCBTB2,TMEM30A,MATN2,NR4A3,CLIP4,CLMN,DYSF,OSMR,ARFGAP3,NFKBIZ,LTBP2,OSR1,ARSB,F2RL1,IFIH1,SERPINB1,LIFR,AHR,TMEM173,JARID2,MAPK12 |
| 2.854e-08 | -17.37 | lung-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-adenocarcinoma | 15921 | 2391 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,DPP8,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,RBM23,MUC16,ENPP5,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,SYP,DNAJB14,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,PLEKHO1,CDCA2,RAB38,PEX5,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ARHGEF40,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,EIF5A2,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,NR1D2,ACVRL1,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,CDC20,DUOX1,ATP1A1,RTN4RL1,PSMD3,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,MRPL44,CDK17,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,GNB2,TMPRSS4,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,FLYWCH2,CAMKK1,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,ABCD4,NKAIN3,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,HP1BP3,PARD3B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PHKG2,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,CD82,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,COL6A2,PFKFB2,SAT1,GIGYF1,EBF2,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,ITGB8,KNDC1,TMEM62,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,PLOD2,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,ARL1,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,STIL,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,IL22RA1,PARM1,VPS26A,FZD6,SH2D4A,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,CAPN12,GPR107,REPS2,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,CCDC110,BLCAP,FTH1,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,TMTC2,CD40,HSF4,ALDH5A1,STAT6,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,CARD8,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,WDR72,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,PIK3AP1,SLC16A6,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,CYHR1,ZNF75D,CNNM4,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 2.874e-08 | -17.36 | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | MSigDB lists | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | 557 | 129 | 17758 | 2588 |
DOC2A,PPP4R4,ACVR1,FAM160B1,PLXNA1,FAM46C,ELMOD2,CHST2,GRM5,RAB15,GRHL1,DPYSL2,MKRN3,PIK3CD,SLC39A10,ANO4,STK35,NEK4,PCGF5,RNF165,BNIP3L,GALNT7,PPP1R14C,PTGFRN,ZFAND5,PNKD,ARF4,EDNRA,HLF,CAMK2N2,P4HA2,DOLPP1,TMOD2,GLCCI1,CCDC97,SEMA6B,RUNX2,PPP1R12A,ZCCHC24,ITGA6,ADO,SOX9,PDCL,PSMD7,SSX2IP,NCAM1,KCTD3,TSPAN33,TMED2,NAGPA,KCNJ12,MMD,LPGAT1,MYBL2,KDM3A,NFIB,RASA1,RHOB,GLCE,COL13A1,CSNK1G1,SETD3,PCDH19,FGD6,NR4A2,STK39,MAP3K5,SEMA3A,RARG,CCNE2,GRHL2,FAM91A1,BAHD1,PER2,ACAP2,RNF220,KHNYN,WDR44,VAT1,ESPN,PDE4D,SCN2A,SCYL3,SCN3A,TBC1D10B,SIRT1,SEC23A,SLC5A11,RAB38,DAG1,SP4,SOCS3,CDK19,LIFR,CPEB4,TAB3,CIT,MAN1A2,FRMD6,MIER3,JAG2,SBF1,NFAT5,XPR1,NRP2,SIX4,HDAC9,ZDHHC21,ZFX,UBE2J1,KLF9,SGCB,ATP2B1,AMOTL2,PGM1,SYPL1,BCL9,EIF5A2,MBNL3,PRICKLE1,FAM109A,FNDC3A,GALNT3,TIMP3,RAP2C,UBE2D2,CEP41,CPEB2,TLL2 |
| 2.884e-08 | -17.36 | pancreas | COSMIC cancer mutations | pancreas | 17360 | 2560 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,PPP4R1,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,NUDT8,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ABRACL,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,MMD,ZNF84,KIAA1841,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,SUZ12,CAST,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,ULBP2,DGKG,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,RHBDL3,PTTG1,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,IL22RA1,VPS26A,PARM1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,GPR107,REPS2,CAPN12,DLGAP5,ST14,NDRG1,CERCAM,RALBP1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,TMEM221,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 2.949e-08 | -17.34 | WHITFIELD_CELL_CYCLE_LITERATURE | MSigDB lists | WHITFIELD_CELL_CYCLE_LITERATURE | 44 | 22 | 17758 | 2588 |
CCNE2,PLK1,PSRC1,CENPA,KIF20A,CDC20,RACGAP1,CCNF,CCNB1,CDC25C,CDK1,CDKN2C,TOP2A,CCNA2,PCNA,E2F1,MSH2,AURKA,BUB1,CCNB2,CDKN2D,CKS2 |
| 2.949e-08 | -17.34 | ZHAN_MULTIPLE_MYELOMA_PR_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_PR_UP | 44 | 22 | 17758 | 2588 |
SPC25,DLGAP5,FOXM1,ASPM,CCDC34,RACGAP1,NUSAP1,NUF2,CCNB1,SKA1,CDK1,FANCI,TOP2A,UBE2T,KIF14,PRC1,NEK2,AURKA,KPNA2,UBE2C,CCNB2,E2F8 |
| 3.006e-08 | -17.32 | cell-substrate adherens junction | cellular component | GO:0005924 | 395 | 99 | 17570 | 2579 |
LMO7,SORBS1,ADD1,HSPG2,IQGAP1,SDC1,SLC9A3R2,GNB2,SH3KBP1,CD46,ZYX,CDH1,CTNNB1,P4HB,DNM2,IRF2,KIF22,DIXDC1,CTTN,TLN2,FLOT2,CHP1,LAP3,SNTB2,SYNE2,EZR,TNS1,ALCAM,DAG1,LCP1,TNS4,MPRIP,JAK1,CORO1C,PTK7,LIMK1,TRIOBP,PPP1CB,SPRY4,ARF6,RPL22,HSPB1,CAPN1,CD99,LASP1,FBLIM1,HSP90B1,MRC2,PACSIN2,MPZL1,PPP1R12A,ITGA6,ARHGEF7,SDC4,FLOT1,PDIA3,KIF23,SORBS3,NCKAP1,ICAM1,ITGA2B,CORO1B,CALR,CAPN2,RAC2,TNS3,FLII,VASP,ITGA3,FLRT3,CD9,EPB41L5,DCAF6,ADAM17,RHOA,CASK,PLAUR,FHL2,YES1,AIF1L,ILK,SNTB1,BCAR1,RHOB,EGFR,ARHGAP24,SCARB2,RPL12,RND3,PVRL2,ITGA7,ITGAV,FHL1,HMGA1,ARPC2,CD81,L1CAM,AFAP1,CSRP2 |
| 3.047e-08 | -17.31 | neuron differentiation | biological process | GO:0030182 | 1196 | 246 | 16441 | 2455 |
MYL9,CASP3,EMX1,UGT8,AGRN,CUL4B,RET,EPHA4,MCOLN3,ARFGEF1,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,TMC1,PICK1,PLS3,CALM2,TP73,WEE1,PSMD1,RPS6KA2,CTNNB1,SHC3,DPYSL2,PSMC2,DLG1,DNM2,TRPC1,NTN4,CTTN,MYH14,PACSIN1,ZBTB18,TIAM1,BTBD3,RASGRP1,ATL1,SOD1,CELSR2,RNF165,EZR,TFAP2C,ULK2,ARF4,DPYSL3,HS6ST1,PLCG1,AREG,MAP2,LIMK1,NKD1,UNC5B,PSMC1,MYL12B,SCN5A,RUNX2,USH1C,CDKN1C,RASA2,SOX9,PSMD7,CALM3,CNTNAP2,SLC1A3,DUSP5,RB1,RAC2,VASP,IGF1R,FRY,LRRN2,GATA2,FLRT3,MEGF8,PAK2,COL6A1,PRKG1,PRKCI,CACNA1D,NCAM1,WNT3A,NTN1,DGKG,PSMA5,DPYSL5,RGMB,CALM1,SCRIB,KIF20B,EPHA1,ILK,DPYSL4,NFIB,PSMA4,RANBP9,STX3,RHOB,EGFR,RASA1,CDK5R1,PTPRF,HTT,SEMA4D,MATN2,CLMN,AURKA,PITPNA,NR4A2,EFNA1,B4GAT1,ARPC2,JAK3,TRPC3,SEMA3A,RPS6KA3,KLF7,DRD1,EHD1,SPRED1,PAX6,PSME2,RPS6KA1,IQGAP1,ERBB2,RASGRP3,MICALL2,PHLDA1,PDGFA,ARTN,CDH1,DACT1,LMO4,FRYL,LHX6,SMO,DAB2IP,EPHB4,NOTCH3,ACSL4,DLG3,RASGEF1A,ETV4,SEMA3B,FRS3,CAMSAP3,COL6A2,FZD4,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,FZD7,NFIX,ARHGAP35,EPHA10,IRS2,FYN,RTN4RL1,JAK1,SLC9A6,PSMD3,EFNA5,SPTBN5,NRG1,PLXND1,LIFR,COBL,CTHRC1,COL9A3,FARP1,ARHGEF11,CIT,ARHGEF7,LRP4,SDC4,FLOT1,PBX3,PSMD10,COL4A5,TGFBR1,JAG2,PLPPR4,SPR,FGF19,EFNB1,ITGA2B,NRP2,PPP2R3A,RND1,GBX2,NEO1,HDAC9,KIF5B,ANK1,IGSF9,PTEN,CDK16,KNDC1,BMP7,SGK1,ATP8B1,ERBB3,ERCC2,GFI1,ITM2C,RPGR,S100A6,CAMK2G,FARP2,RASGRF1,HES1,B3GNT2,ARHGEF28,RHOA,PSMB4,WNT10B,FMN1,RAPGEF2,GRIN1,STMN3,RUNX3,YES1,ABLIM2,MAP1B,CNTNAP1,PITX2,PROM1,FAT4,FGFR2,FGF18,NR4A3,RYK,PGRMC1,GRIN2D,ITGAV,FZD5,SOX8,L1CAM,FOXA1,NGEF,RGMA |
| 3.051e-08 | -17.31 | vacuole | cellular component | GO:0005773 | 608 | 139 | 17570 | 2579 |
DOC2A,LAMP1,UNC93B1,GAA,AGRN,HSPG2,HEXB,SDC1,MAP1LC3B,EPDR1,ABCD4,DAPK2,NAPG,PQLC2,AP1M2,ENTPD4,RDH14,ABCA2,AKR1B1,SNX16,TINAGL1,PIK3CD,MARCH2,S100A13,RASGRP1,LAMP3,LAMP2,VPS11,SOD1,SLC17A5,RNF19B,TCN2,RHEB,OPTN,ENPP1,TBC1D17,HPSE,WDR11,WIPI1,GLA,CAPN1,ANXA11,RRAGD,STARD3NL,TMEM55B,RAB23,C6orf106,ASAH1,SLC36A4,MARCH8,GNS,ZNRF2,GATA2,VASN,COL6A1,PCYOX1,CTSD,TMEM8A,C9orf72,MMD,PIP4K2C,CALCRL,NPC2,TP53INP2,GNA11,STX3,C18orf8,NAAA,SCARB2,HTT,CTSA,PLD1,TRIP10,SLC2A8,GNB2,ATP6V0B,SRPX,RALB,RPN2,GOT1,ECE1,LGMN,TSPAN1,OSBPL7,TMEM9,NAGA,TMBIM1,GM2A,EVA1A,NRBF2,OSTM1,AP5M1,SLC11A2,ATP13A2,GABARAPL1,RAB29,MAN2B2,SORT1,CD63,CTSB,ARHGEF7,CIT,SDC4,FLOT1,CTSZ,M6PR,TMEM63A,CAPN2,CTSC,ARSG,GPC3,GALNS,CST3,DRAM1,SLC44A2,PLEKHF1,ITM2C,TPCN1,MYO5A,P2RX4,GUSB,IFITM3,LITAF,GGH,GPLD1,USP6,BCL10,CTSL,FUCA1,CTNS,SYT7,PRCP,CTSV,PLA2G15,NR4A3,ARRB1,GLB1,ATP6V1C1,ARSB |
| 3.075e-08 | -17.30 | focal adhesion | cellular component | GO:0005925 | 390 | 98 | 17570 | 2579 |
LMO7,SORBS1,ADD1,HSPG2,IQGAP1,SDC1,SLC9A3R2,GNB2,SH3KBP1,CD46,ZYX,CDH1,CTNNB1,P4HB,DNM2,IRF2,KIF22,DIXDC1,CTTN,TLN2,FLOT2,CHP1,LAP3,SNTB2,SYNE2,EZR,TNS1,ALCAM,DAG1,LCP1,TNS4,MPRIP,JAK1,CORO1C,PTK7,LIMK1,TRIOBP,PPP1CB,SPRY4,ARF6,RPL22,HSPB1,CAPN1,CD99,LASP1,FBLIM1,HSP90B1,MRC2,PACSIN2,MPZL1,PPP1R12A,ITGA6,ARHGEF7,SDC4,FLOT1,PDIA3,KIF23,SORBS3,NCKAP1,ICAM1,ITGA2B,CORO1B,CALR,CAPN2,RAC2,TNS3,FLII,VASP,ITGA3,FLRT3,CD9,EPB41L5,DCAF6,ADAM17,RHOA,CASK,PLAUR,FHL2,YES1,AIF1L,ILK,SNTB1,BCAR1,RHOB,EGFR,ARHGAP24,SCARB2,RPL12,RND3,PVRL2,ITGAV,FHL1,HMGA1,ARPC2,CD81,L1CAM,AFAP1,CSRP2 |
| 3.128e-08 | -17.28 | activation of protein kinase activity | biological process | GO:0032147 | 456 | 112 | 16441 | 2455 |
SPRED1,TXN,AVPI1,PSME2,CAMKK1,NRG2,P2RX7,ERBB2,RASGRP3,PSME1,PRKACA,PDGFB,ERP29,EMP2,CARD10,SPTB,GRM5,TP73,CALM2,PDGFA,PAK6,PSMD1,SHC3,KIF14,PSMC2,PIK3CA,DLG1,DAB2IP,RASGEF1A,F2R,RASGRP1,FRS3,MAP3K3,NEK4,SOD1,RIPK2,PRKAR2B,CDK1,MAP3K6,IRS2,PLCG1,FYN,GPRC5B,JAK1,STK26,PSMD3,MADD,KIAA1804,NOD2,MAP3K11,CAB39,EFNA5,SPTBN5,NRG1,PSMC1,GAB1,PRKAR1A,PINK1,TAOK2,NKX3-1,TAB3,RASA2,TRAF2,PRKAA1,PSMD7,CALM3,PSMD10,TGFBR1,PKN1,DUSP5,FGF19,BMP2,ADORA1,IRAK1,PAK2,MAP3K9,MAPK11,MDFIC,ERBB3,NCAM1,MAP3K7,IQGAP3,SYK,CAMK2G,CCDC88A,PSMA5,MDFI,PDGFC,RASGRF1,PSMB4,MAPKAPK3,RAPGEF2,CALM1,GRIN1,RGCC,STRADB,PSMA4,EGFR,RASA1,MAPKAPK2,INSR,PRKAG2,FGFR2,FGF18,ARRB1,PPP2R3C,GRIN2D,STK39,EFNA1,MAP3K5,CD81,JAK3 |
| 3.187e-08 | -17.26 | KINASE_ACTIVITY | MSigDB lists | KINASE_ACTIVITY | 367 | 93 | 17758 | 2588 |
ACVR1,RPS6KA1,DGKA,ETNK1,ERBB2,TESK2,MAPK4,PDGFRL,DDR1,FLT3,DAPK2,RPS6KA2,PLK4,DLG1,PIK3CA,PHKA2,MAP3K3,PLK1,NEK4,MARK1,AKT1,RIPK2,PFKFB2,ACVR1C,PBK,ROR1,XRCC6BP1,MAP3K6,STK17B,CDK1,STK38,PTK7,AXL,LIMK1,MYLK,MAP3K11,MAPK13,PDXK,ITPKA,MAPK12,GALK1,PINK1,TAOK2,CIT,GNE,DGKQ,TGFBR1,TRIB2,MERTK,NRP2,IRAK1,IGF1R,ARSG,PFKL,PAK2,PRKCI,MAP3K9,NEK2,SGK3,SGK1,MAPK11,PIM1,ERBB3,PIKFYVE,MAPK7,MAP3K7,DGKG,PHKG2,CASK,TESK1,MAPKAPK3,MPP1,STRADB,EIF2AK1,PDK3,ILK,DGKE,CDK5R1,EGFR,STK17A,TXK,MAPKAPK2,INSR,ACVRL1,DCK,PRPS2,MPP2,RYK,NR4A3,MAP3K5,HIPK3,RPS6KA3,DMPK |
| 3.239e-08 | -17.25 | AKT_UP_MTOR_DN.V1_UP | MSigDB lists | AKT_UP_MTOR_DN.V1_UP | 171 | 53 | 17758 | 2588 |
MAN2B2,TPRN,GGA1,CAMKK1,PSMD7,C6orf106,FBXO6,TMPRSS4,KCTD9,PARM1,SGPL1,TMCC3,CXCL16,IGF1R,A4GALT,KCNK5,SLC44A1,DUSP10,VAT1,TNFRSF12A,TACSTD2,IFIT1,LGMN,NFKB2,CPE,TTLL1,DUSP1,MYO5B,TGIF1,CD55,PLSCR1,GUSB,SLC39A8,C3orf52,PYGL,AK4,PDK3,RAB3IP,FXR2,RNF19B,SEC14L2,NIN,IL1R1,SLC6A6,PTPRJ,CTNS,TJP3,GDE1,PLK2,MPP2,CLMN,SH3BGRL2,MAL2 |
| 3.357e-08 | -17.21 | LIAO_METASTASIS | MSigDB lists | LIAO_METASTASIS | 499 | 118 | 17758 | 2588 |
FAM171B,FOXO6,SLC25A24,UPF3B,GPR107,NQO1,AGRN,FOXM1,FAM199X,ST14,VANGL1,TRIP10,GNPDA1,FAM129B,MCOLN3,NUF2,GRK6,PLXNA1,BARD1,MXD1,PDGFA,NPNT,PAQR5,CAPG,SERINC2,TRPC1,TAX1BP3,TWIST1,SLC39A10,LRP11,RCAN3,TMEM200B,SOAT1,ORAI2,KIFC2,CBX6,TFAP2C,ITPR3,KCTD2,PTGFRN,ZNF618,SLC44A3,ATP13A2,PGF,ANKRD10,DNAJC10,GPRC5B,DDOST,PAFAH1B3,POPDC3,DHRS13,MAP2,DNM1L,PPP2R4,ZNF704,HDAC1,VSIG10,MAPK13,ARHGAP4,TRAF5,CCDC97,RRAGD,PCSK5,CTHRC1,LASP1,FBLIM1,FARP1,PACSIN2,SORT1,ENO2,CDKN1C,SERPINE2,HJURP,FXYD3,SOX9,INTS8,FBLN1,SAC3D1,PDIA4,SLC25A36,MECOM,CD109,ZNF432,B3GALNT1,CARD8,ZCCHC17,UBE2Q2,IRAK1,CTSC,MYLIP,MPHOSPH9,CKAP4,IGSF3,MMD,NUB1,MRS2,MYBL2,WHSC1,SCRIB,MAP1B,GNAS,DGCR2,ZMYND19,NEIL3,AMMECR1,CDCA7L,SLC2A6,E2F1,NETO2,ALPK3,STK39,HMGA1,PLD1,NDE1,SERPINB1,CBX5,PTGES,DEF6 |
| 3.429e-08 | -17.19 | ONDER_CDH1_TARGETS_1_UP | MSigDB lists | ONDER_CDH1_TARGETS_1_UP | 131 | 44 | 17758 | 2588 |
PRSS8,ALDH6A1,IL15,TSC22D3,INPP5D,FBXO2,GDF15,DNAJB9,H1FX,PER2,KHNYN,CYP4F11,METTL7A,BHLHE41,LHX6,BCL6,CDKN1B,CD70,IGFBP2,HSPA13,KLF9,CTTN,IL1RAP,CTH,EPHX1,CYP1B1,GFPT1,CD55,CELSR2,ADCK3,GCLC,CRIP2,KDELR3,LEPR,CYP4F3,EGFR,GABARAPL1,MAGED2,PRKAG2,NR1D2,WIPI1,FAM117A,CSRP2,ABCG1 |
| 3.436e-08 | -17.19 | PTCH1 (patched 1) | protein interactions | 5727 | 94 | 37 | 16036 | 2547 |
UGT8,ITGA6,CACNA2D2,COL18A1,PLXNA1,CCNB1,HLA-A,KIAA1161,CHPF,WWP2,TGFBR3,MGAT1,IMPAD1,SMO,ABCA2,CNNM4,WWP1,HLA-C,MOXD1,MGAT5,GCNT1,SULF2,ADAM17,ITCH,CASP9,FHL2,GALNT7,PXYLP1,ARSK,CDK1,EGFR,ENPP1,ITGA7,NETO2,B4GALT3,POMGNT2,TMEM131 |
| 3.468e-08 | -17.18 | cell morphogenesis involved in neuron differentiation | biological process | GO:0048667 | 719 | 161 | 16441 | 2455 |
MYL9,AGRN,EPHA4,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,RPS6KA2,PSMD1,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,MYH14,BTBD3,TIAM1,RASGRP1,ATL1,SOD1,CELSR2,RNF165,EZR,ULK2,DPYSL3,PLCG1,MAP2,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,PSMD7,CALM3,SLC1A3,DUSP5,RAC2,RB1,VASP,IGF1R,LRRN2,FLRT3,COL6A1,PAK2,CACNA1D,NCAM1,WNT3A,NTN1,PSMA5,DPYSL5,RGMB,CALM1,SCRIB,EPHA1,DPYSL4,RANBP9,NFIB,PSMA4,EGFR,RASA1,CDK5R1,RHOB,SEMA4D,MATN2,PITPNA,NR4A2,EFNA1,B4GAT1,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,KLF7,SPRED1,PSME2,RPS6KA1,ERBB2,RASGRP3,PDGFA,ARTN,DACT1,DAB2IP,EPHB4,RASGEF1A,DLG3,ETV4,FRS3,SEMA3B,COL6A2,SLC11A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,IRS2,EPHA10,FYN,JAK1,SLC9A6,PSMD3,SPTBN5,EFNA5,NRG1,PLXND1,COBL,COL9A3,FARP1,ARHGEF11,ARHGEF7,LRP4,FLOT1,PSMD10,COL4A5,PLPPR4,SPR,FGF19,EFNB1,ITGA2B,NRP2,NEO1,GBX2,RND1,KIF5B,ANK1,PTEN,BMP7,ERBB3,S100A6,CAMK2G,FARP2,HES1,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,FMN1,RAPGEF2,GRIN1,YES1,ABLIM2,MAP1B,CNTNAP1,FGFR2,FGF18,NR4A3,PGRMC1,RYK,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 3.611e-08 | -17.14 | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN | 190 | 57 | 17758 | 2588 |
ARHGAP11A,DOC2A,CASP3,FARP1,GNPDA1,TUBB4B,CKAP2,SLC25A13,SERPINB9,APOO,CDCA8,LACTB2,BARD1,PHLDA1,HLA-A,MAGOHB,CCNA2,RRBP1,RANBP1,PRC1,CKS1B,KIF22,MDFIC,ALDH7A1,KNTC1,MANF,TIAM1,TSPAN33,PSMA5,SEPHS1,PLK1,MLEC,PLSCR1,FIGNL1,PBK,DSTN,CDC20,MBNL3,LITAF,CCDC34,AURKB,DUSP4,SAV1,FRMD4B,PRIM1,CASP7,NEIL3,ZNF367,CDCA5,PGRMC1,KPNA2,GEM,NUP37,CCNB2,E2F8,ACOT7,MELK |
| 3.611e-08 | -17.14 | GSE29618_BCELL_VS_PDC_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DN | 190 | 57 | 17758 | 2588 |
TXN,RUNX2,HSP90B1,MPZL1,TRIP10,ST14,DNAJC3,NDRG1,CTSB,PDIA3,NDUFA4,MGST2,PLA2G16,NUCB2,SLC20A1,FLT3,IL18R1,DUSP5,BCAP31,SSX2IP,KIF5B,RPS6KA2,TM9SF2,CTSC,DPYSL2,RIMS3,RRBP1,PRKCI,UBE2J1,RPN2,TAGLN2,MARCH2,LGMN,EGLN3,PTPRE,ITM2C,NAGA,CCDC88A,SEPHS1,UFD1L,MLEC,SEC61B,PFKFB2,DSTN,RNF11,CBX6,NPC2,LHFPL2,MYL12A,ATP13A2,MAPKAPK2,PIAS3,SCARB2,CORO1C,SH3BP4,IRF7,TBC1D4 |
| 3.611e-08 | -17.14 | GSE3982_MAST_CELL_VS_DC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_DC_DN | 190 | 57 | 17758 | 2588 |
GAS2L1,SORT1,CDS2,LRRFIP2,NFKBIE,MPZL1,IL15,GALNT12,SDC4,MCOLN3,FAM134A,RAB23,IL13RA1,FAM198B,NANS,VASH1,BARD1,PPP2R3A,EPCAM,SNX13,SPP1,DNPEP,CA2,IGF1R,RAB20,TACSTD2,CTTN,SYK,RBMS2,CKAP4,LAMP3,GUSB,ADCK3,DIAPH2,PRKAR2B,ALCAM,GNA11,ULK2,RHEB,CYB5A,DNAJC10,FA2H,ACADSB,PRDX3,C19orf66,WIPI1,RAB31,OTUB2,CLIP4,MDH1,RGS14,RAP1GAP,ARSB,SLC31A2,ANXA11,ACOT7,CSRP2 |
| 3.618e-08 | -17.13 | positive regulation of GTPase activity | biological process | GO:0043547 | 499 | 120 | 16441 | 2455 |
ARHGAP11A,PLEKHG3,AGRN,RALBP1,IQGAP1,ARFGEF1,RGS20,ERBB2,F11R,RASGRP3,SNX9,DENND2D,RIC1,ELMOD2,ARHGEF16,EPS8L2,ARHGEF10L,SIPA1L2,ST5,ARHGAP42,ACAP2,RGS12,RABEP2,SH3BP1,CDKL5,ARHGEF37,RGS3,TAX1BP3,RGS5,RP2,RASGEF1A,TIAM1,RASGRP1,TBC1D10B,DOCK4,ARHGDIB,CD40,DOCK5,ABR,ARHGEF26,ARHGAP35,PLEKHG6,TBC1D17,ARHGEF19,SH2D3C,CORO1C,MADD,SIPA1L1,PLEKHG1,AGFG2,ARHGAP4,RGS14,RAP1GAP,STARD13,FGD1,DENND5B,ARFGEF3,ARHGEF3,FARP1,ARAP3,DEPDC1,ARHGEF11,TBC1D1,ITGA6,ARHGEF7,RASA2,RACGAP1,DOCK11,SBF1,ARHGEF40,ICAM1,SYDE2,SNX13,RALGPS2,SNX18,RINL,LLGL2,KNDC1,OCRL,MCF2L,RANBP1,FAM13B,TBCD,FNIP1,IQGAP3,ALS2CL,RPGR,FARP2,RASGRF1,ARAP2,ARHGEF28,TBC1D8B,DENND1B,RAPGEF2,SPATA13,FBXO8,SCRIB,EPHA1,RAB3IP,GRTP1,RASA1,RASGRP2,GNAS,BCAR3,ARHGAP24,TSC1,RGS9,SEMA4D,RCBTB2,RIN3,ARAP1,FGD6,ARFGAP3,ARRB1,TBC1D4,ARHGEF9,RAB3IL1,ARHGEF4,NGEF,DOCK9 |
| 3.648e-08 | -17.13 | regulation of locomotion | biological process | GO:0040012 | 725 | 162 | 16441 | 2455 |
ACVR1,TRIM5,ATP8A1,RET,GATA3,PLXNA1,CAMK1D,VASH1,HDAC6,PDGFB,GRM5,HTR1D,EPCAM,DAPK2,P4HB,TNFRSF18,TACSTD2,SEMA3G,PIK3CD,CYP1B1,TRIM8,ACVR1C,ARHGDIB,ABR,DPYSL3,PLCG1,MYLK,NKD1,FAM110C,NOD2,HSPB1,F2RL1,GAB1,MIIP,DDX58,SEMA6B,ARAP3,SERPINE2,LGALS3,BVES,SOX9,FBLN1,LMNA,SSX2IP,CORO1B,BMP2,CALR,RAC2,ITGA3,TIMP1,IGF1R,CYR61,MEGF8,SORL1,NTN1,WNT3A,EPB41L5,ANO6,SPATA13,KIF20B,EPHA1,ILK,RHOB,EGFR,STX3,ONECUT1,AP1AR,INSR,SEMA4D,PVRL2,PLPP3,CSF1,EGFL7,EFNA1,PLD1,CFAP20,SEMA3A,DRD1,NF2,PKP2,COL18A1,CD274,EMP2,PDGFA,SVBP,NOV,ARTN,SP100,KIF14,DAB2IP,TWIST1,EPB41L4B,PDE4D,F2R,SEMA3B,DOCK4,BAG4,AKT1,PTPRU,DMTN,CCSAP,SYNE2,PTGER4,DOCK5,DAG1,IRS2,PTGS2,PTPRJ,CORO1C,NRG1,PLXND1,ARHGAP4,TCAF1,ANXA3,ADGRG1,ARHGEF7,SDC4,SELL,CBLL1,PLD2,JAG2,PKN1,ETS1,SRPX2,ICAM1,PPP2R3A,NRP2,ITGA2B,HDAC9,CXCL16,PDCD10,ADORA1,PTEN,SGK3,SGK1,TRIM21,ADAM15,CITED2,TRIM62,SUN2,RHOA,ADAM17,IFITM3,MPP1,RAPGEF2,PIK3R1,RGCC,FURIN,BBS2,BCAR1,GPLD1,SWAP70,ACVRL1,SCG2,PRCP,SPINT2,RAP2C,FGF18,ITGAV,GPER1,ARSB,CD81 |
| 3.742e-08 | -17.10 | KIM_WT1_TARGETS_UP | MSigDB lists | KIM_WT1_TARGETS_UP | 209 | 61 | 17758 | 2588 |
CCNE2,PLEKHG3,CDK17,NFKBIE,ENO2,SOX9,SDC4,BAHD1,SLC20A1,ETS1,CARD10,DUSP5,IER3,PDGFA,RAB15,ZYX,TNS3,CA2,CYR61,CALD1,ATP13A3,MAP3K9,PRKCI,SGK1,TNFRSF12A,KLF9,NFKB2,TIAM1,PTPRE,ZNF365,SPRY2,IL1RAP,MSH6,ATP2B1,ARAP2,MBP,B3GNT2,NR3C1,NR4A1,PLAUR,C3orf52,FHL2,LITAF,TNS1,ATP1B1,SRSF5,CD83,TIMP3,AREG,RND3,KCNK1,PHLPP2,CSF1,WWTR1,NFKBIA,HMGA1,GEM,ZMIZ1,ST3GAL1,COBL,MAFF |
| 3.790e-08 | -17.09 | GTGCCAA,MIR-96 | MSigDB lists | GTGCCAA,MIR-96 | 287 | 77 | 17758 | 2588 |
FAF2,GRHL2,TSC22D3,XIAP,CACNA2D2,RHPN2,ITPR2,MORF4L2,CACNB4,SH3KBP1,CABP1,MITF,KLF3,ABCA2,VAT1,SNX16,NTN4,EPB41L4B,SLC39A10,FLOT2,BTBD3,MYRIP,HSPA2,SCYL3,STK35,MAP3K3,LAMP2,PCGF5,HN1L,CELSR2,PTPN9,CBX6,EZR,LDB2,ZFAND5,LCP1,FYN,GPRC5B,TBX1,LRIG1,ZNF704,OVOL1,CTNND1,EIF4EBP2,AIFM3,COBL,ABCA1,PRKAR1A,CTDSP1,DLAT,FARP1,SORT1,CPEB4,RAB23,TGFBR1,FAM81A,TTYH3,PGAP1,SLC9A2,B4GALNT1,HDAC9,TNS3,GPC3,TMBIM6,ABCD1,SLC35A1,TMX1,PHF20L1,TACC1,BSDC1,ARHGAP24,DDAH1,COL13A1,PLOD2,CSF1,RYK,NR4A3 |
| 3.854e-08 | -17.07 | GSE7852_LN_VS_FAT_TREG_DN | MSigDB lists | GSE7852_LN_VS_FAT_TREG_DN | 195 | 58 | 17758 | 2588 |
CD99,IER5L,INPPL1,IQGAP1,WDTC1,KIF23,PBX3,RBP7,PHLDA1,TNFSF9,BEX2,EPM2A,DNAJB9,UHRF1BP1L,IER3,CAPN2,OSBPL3,MITF,DRAM1,RAB20,RGS5,ARNT2,TMEM64,NCEH1,TMBIM1,DUSP1,RASGRF1,TGIF1,FZD4,MAPKAPK3,ADCK3,PARD3B,RAPGEF2,SYNE2,MGAT4B,CRIP2,PLEKHA7,PRKAR2B,TMTC2,ALCAM,RHOB,CARHSP1,HLF,MID1IP1,AGPAT2,ETS2,NR4A3,CSGALNACT1,PCDH19,PRKCDBP,PKD2,RELL1,GRAMD1C,FZD5,L1CAM,MAFF,COL16A1,TOB1 |
| 3.858e-08 | -17.07 | SMIRNOV_RESPONSE_TO_IR_6HR_DN | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_DN | 110 | 39 | 17758 | 2588 |
ARHGAP11A,KLF2,DLGAP5,ZNF395,DEPDC1,ATP8A1,CDCA3,C5orf30,KIF23,KCTD12,EGR3,CCNB1,H1FX,CD22,ZFP36,KIF14,NEK2,BUB1,EGLN3,HMMR,PLK1,SUN2,CD55,CENPA,PSRC1,KIF20A,ASPM,CDC20,CR2,KDM3A,CDK5R1,H1F0,AURKA,NR4A2,CENPE,UBE2C,TRAF5,MAFF,EGLN1 |
| 3.974e-08 | -17.04 | COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | MSigDB lists | COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | 348 | 89 | 17758 | 2588 |
UPF3B,DLGAP5,FOXM1,HEXB,PPFIBP2,NDC80,IL13RA1,NUF2,KIF2C,GALM,CCNB1,PHLDA1,CCND1,SESN3,CCNA2,SRPX,UBE2T,TSPAN6,OSBPL3,KIF22,TINAGL1,PHKA2,SCARA3,S100A13,LAMP2,PLK1,SMARCA2,RFK,LGALS8,PBK,USP18,CDC20,CCBL2,NUSAP1,AURKB,ATP1B1,ANLN,SESN1,ATP10D,IRX3,BHLHB9,TBX1,STAT1,GLA,GLCCI1,GRN,PARP12,ENO2,BACE1,BLVRB,SDC4,ABCG2,RACGAP1,HOXB2,TSPAN17,LGALS3BP,NEO1,FOXP2,TOP2A,RNF128,PFKL,NEK2,FXYD5,ALDH7A1,IGFBP2,RFX5,HLA-C,SLC12A2,HMMR,P2RX4,PGM1,ALDH2,KIF20A,IFITM3,VAMP3,RNF113A,NFIB,FUCA1,PTPRF,DDAH1,SCARB2,PLOD2,FGF18,ACADM,LTBP2,OSR1,ESPL1,MELK,FOXA1 |
| 4.026e-08 | -17.03 | GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | MSigDB lists | GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | 172 | 53 | 17758 | 2588 |
HSP90B1,DLGAP5,SLC16A14,CENPI,PTTG1,PDIA5,C5orf30,DNAJB11,RASGRP3,NUF2,CHAC2,CCNB1,TMEM19,SDC1,STIL,PARM1,ARL1,FICD,BHLHE41,SLC44A1,UBE2J1,SRP54,RPN2,BUB1,MANF,LMAN1,FAIM,MOXD1,ITM2C,HMMR,ERLEC1,CXXC5,SEC61B,PBK,C3orf52,CDC20,TMEM133,GGH,EAF2,TXNDC11,CDK1,GPLD1,PRDX4,TRAM2,FASTKD1,SLC25A4,ACADM,B4GALT3,GLCCI1,GEN1,CCNB2,E2F8,DENND5B |
| 4.090e-08 | -17.01 | GSE14350_IL2RB_KO_VS_WT_TREG_DN | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TREG_DN | 200 | 59 | 17758 | 2588 |
FAM89A,HECA,CCDC109B,SERPINE2,LGALS3,SLC16A14,CKAP2,DAP,NDRG1,SDC4,MMADHC,NDRG2,HMGN3,ADAMTSL4,REPS1,C1orf116,HDAC9,EPCAM,APOBEC3B,CDKN2C,CTGF,KCNN4,TSPAN6,OSBPL3,SORL1,NTN4,TMBIM1,EPHX1,ELK3,S100A4,SAT1,CBX6,WHSC1,TMTC2,POLD3,SESN1,ALCAM,TCN2,CD83,DGKH,RGS9,PTPRJ,SWAP70,TWSG1,H1F0,ANKRD6,AXL,PELI2,SERPINB6,EPB41L4A,TTC39C,GLCCI1,CD81,F2RL1,L1CAM,CSRP2,XDH,RRAGD,MAPK12 |
| 4.136e-08 | -17.00 | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | MSigDB lists | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | 186 | 56 | 17758 | 2588 |
SLC25A24,CDKN1C,IBTK,ARHGEF11,FRMD6,ZCCHC24,EPHX4,ERI2,C1orf198,P2RX7,TDRKH,VARS2,GPSM2,SNN,COX6C,TMCC3,RCN1,RB1,FRY,PPP4R1,POLL,MDFIC,TMEM64,ZRANB1,TIAM1,NEB,S100A13,RASGRP1,GM2A,ATP2B1,REC8,PCCB,GCC2,CENPA,IFITM3,CEP89,BCL9,UBE2A,PRICKLE1,VWA1,CAPNS1,NUSAP1,DNAJB14,ZFAND5,NFIX,OSBPL2,FAM177A1,ETS2,WFS1,SH3GLB2,CSGALNACT1,SH3BGRL2,PLXND1,CENPE,CD81,CTBP1 |
| 4.138e-08 | -17.00 | breast-carcinoma-lobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-lobular_carcinoma | 784 | 169 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,GATA3,CAMK1D,SPTB,CDKN2C,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,MITF,PIK3CA,CTTN,STK35,PLK1,NEK4,MARK1,CELSR2,ACVR1C,PBK,ARFRP1,ROR1,AURKB,IDH1,ADRBK2,STK17B,ULK2,PLCG1,RBM47,PLK2,LIMK1,GNPTAB,MYLK,MAP3K11,MAPK13,NFKBIZ,RNASEL,PCSK5,PRKAA2,CDK17,PRKAA1,ADCK5,MERTK,BMP2K,RB1,IGF1R,NEK2,MSH2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,PHKG2,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,GNA11,EGFR,STK17A,GNAS,MAPKAPK2,TSC1,CACHD1,INSR,UTP14C,PHLPP2,ALPK3,AURKA,CDK18,PLD1,MAP3K5,JAK3,NRBP1,RPS6KA3,RUSC1,DMPK,NF2,FAM92A1,RPS6KA1,TP53,TESK2,ERBB2,GRK6,BCL2L1,PRKACA,FLT3,DDR1,CDK14,CCND1,TTC21B,SAP130,CDH1,PLK4,BCL6,SMO,RNASEH2A,EPHB4,SCYL3,MAP3K3,RIPK2,AKT1,SYNE2,KIF1C,PRKCQ,PKMYT1,CBL,MAP3K6,IRS2,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,MAMDC2,MAPK12,PINK1,DYRK3,TAOK2,ARHGEF11,TRAF2,TGFBR1,PKN1,TRIB2,HDAC9,ADRBK1,IRAK1,PTEN,CDK16,MYCL,SGK3,SGK1,BUB1,MAPK11,ERCC2,ERBB3,MAP3K7,SYK,CAMK2G,ATP2B1,MSH6,NFE2L3,CASK,PIK3R1,YES1,SNTB1,POLD3,TXK,FGFR2,ACVRL1,ITGAV,SHOX2,HIPK3,MELK |
| 4.138e-08 | -17.00 | lobular_carcinoma | COSMIC cancer mutations | lobular_carcinoma | 784 | 169 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,GATA3,CAMK1D,SPTB,CDKN2C,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,MITF,PIK3CA,CTTN,STK35,PLK1,NEK4,MARK1,CELSR2,ACVR1C,PBK,ARFRP1,ROR1,AURKB,IDH1,ADRBK2,STK17B,ULK2,PLCG1,RBM47,PLK2,LIMK1,GNPTAB,MYLK,MAP3K11,MAPK13,NFKBIZ,RNASEL,PCSK5,PRKAA2,CDK17,PRKAA1,ADCK5,MERTK,BMP2K,RB1,IGF1R,NEK2,MSH2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,PHKG2,ADCK3,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,GNA11,EGFR,STK17A,GNAS,MAPKAPK2,TSC1,CACHD1,INSR,UTP14C,PHLPP2,ALPK3,AURKA,CDK18,PLD1,MAP3K5,JAK3,NRBP1,RPS6KA3,RUSC1,DMPK,NF2,FAM92A1,RPS6KA1,TP53,TESK2,ERBB2,GRK6,BCL2L1,PRKACA,FLT3,DDR1,CDK14,CCND1,TTC21B,SAP130,CDH1,PLK4,BCL6,SMO,RNASEH2A,EPHB4,SCYL3,MAP3K3,RIPK2,AKT1,SYNE2,KIF1C,PRKCQ,PKMYT1,CBL,MAP3K6,IRS2,EPHA10,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,MAMDC2,MAPK12,PINK1,DYRK3,TAOK2,ARHGEF11,TRAF2,TGFBR1,PKN1,TRIB2,HDAC9,ADRBK1,IRAK1,PTEN,CDK16,MYCL,SGK3,SGK1,BUB1,MAPK11,ERCC2,ERBB3,MAP3K7,SYK,CAMK2G,ATP2B1,MSH6,NFE2L3,CASK,PIK3R1,YES1,SNTB1,POLD3,TXK,FGFR2,ACVRL1,ITGAV,SHOX2,HIPK3,MELK |
| 4.218e-08 | -16.98 | negative regulation of apoptotic process | biological process | GO:0043066 | 826 | 180 | 16441 | 2455 |
CASP3,ACVR1,GRIK2,TSC22D3,FAM129B,DNAJC3,XIAP,GATA3,PSME1,CAMK1D,BARD1,TP73,EPCAM,PSMD1,CTNNB1,IL6ST,PSMC2,IL31RA,MITF,PIK3CA,TNFRSF18,CTTN,ARNT2,SLC39A10,ANKRD9,PLK1,SOD1,ITCH,BNIP3L,AURKB,SLC25A5,CDK1,POR,ARF4,OPTN,MDK,PLK2,TBX1,MADD,NOD2,HDAC1,UNC5B,HSPB1,PSMC1,PRKAA2,BMF,LGALS3,ITGA6,SOX9,PRKAA1,PSMD7,SLC25A27,NOTCH2,MERTK,LMNA,TIMP1,IGF1R,CYR61,PAK2,MSH2,DAPK1,PRKCI,FNIP1,MYDGF,PIM1,MAPK7,PSMA5,OXR1,FHL2,STRADB,IFIT3,ILK,PSMA4,EGFR,G2E3,RASA1,FAS,SEMA4D,HTT,NFKBIA,AURKA,NR4A2,JAK3,RARG,IFI6,RPS6KA3,RPS6KA1,PSME2,CAST,TP53,SOD2,ERBB2,EGR3,BCL2L1,STIL,IER3,KIF14,BCL6,SMO,CDKN1B,TWIST1,APIP,LGMN,CDKN2D,F2R,TMBIM1,CTH,SIRT1,PPIF,BAG4,RIPK2,AKT1,FIGNL1,HTATIP2,PRKCQ,GLO1,CBL,SOCS3,IRS2,FYN,BHLHB9,AXL,WFS1,PSMD3,TLE1,NRG1,IRF7,AREL1,LIFR,CBX4,ZC3HC1,FAM134B,GCLM,PINK1,HSP90B1,CPEB4,TRAF2,SERPINB9,PSMD10,NES,TGFBR1,GSTP1,ICAM1,SIX4,PDCD10,ADORA1,IRAK1,PTEN,BMP7,TFAP2A,BAX,TMBIM6,ERBB3,CITED2,FAIM,RAG1,MAP3K7,SPRY2,DUSP1,RHOA,PSMB4,HMGN5,PLAUR,GCLC,PIK3R1,GRIN1,PELI3,PIM3,MAPK8IP1,BCL10,FGFR2,SCG2,PRDX3,DHRS2,NR4A3,ARRB1,ITGAV,OSR1,SOX8,HIPK3 |
| 4.250e-08 | -16.97 | positive regulation of cell communication | biological process | GO:0010647 | 1574 | 310 | 16441 | 2455 |
TXN,ACVR1,LGR4,GRIK2,TRIM5,RET,XIAP,NRG2,GATA3,PSME1,IL18,SEPT4,SLC20A1,CARD10,GRM5,TP73,CALM2,PSMD1,TGFBR3,CTGF,IL31RA,PPP1CA,TFG,SH3BGRL,POR,PLCG1,DNM1L,ANKRD6,PLK2,SH2D3C,TBX1,NKD1,FAM110C,NOD2,MAP3K11,TMOD2,UNC5B,TRAF5,F2RL1,GAB1,CDKN1C,SCOC,SOX9,PRKAA1,NOTCH2,SLC1A3,TNFRSF19,KIAA1161,TFAP4,WDFY1,CYR61,PIK3AP1,MAP3K9,TNFRSF12A,MYDGF,NCAM1,TSPAN33,RIMS2,EEF1D,KLK5,MAPKAPK3,CALM1,AMER1,SHARPIN,PIP4K2C,ILK,PSMA4,STX3,RASA1,FAS,HTT,SEMA4D,PELI2,EFNA1,GDF11,MAP3K5,RUSC1,XDH,SPRED1,LFNG,BCL2L1,FLT3,EPM2A,NOV,ST5,RNF220,RALB,DACT1,DAB2IP,RASGEF1A,NR2C1,CDKN2AIP,RIPK2,FZD4,PFKFB2,DMTN,CLSTN1,PRKCQ,CBL,ITPR3,FZD7,IRS2,FYN,JAK1,AXL,KIAA1804,NRG1,RGS14,ARNT,NKX3-1,TAOK2,TRAF2,EPS8,BIK,FLOT1,PDIA3,PKN1,TSPAN17,FGF19,ICAM1,NEO1,PDCD10,OXCT1,IRAK1,CTSC,PTEN,GPC3,BAX,PLEKHF1,SLC44A2,MAPK11,ERBB3,CITED2,MAP3K7,GFI1,ITM2C,SPRY2,TRIM62,RASGRF1,RAPGEF2,PIK3R1,GRIN1,FURIN,TXK,GPLD1,CNTNAP1,LDLRAP1,FGFR2,ACVRL1,DBI,RYK,GRIN2D,GPER1,LRRK1,FZD5,CD81,SHOX2,FOXA1,ILDR1,EPHA4,LMCD1,ARFGEF1,NENF,HDAC6,PDGFB,ERP29,SPTB,CTNNB1,NPNT,SHC3,IL6ST,TSPAN6,SIVA1,PSMC2,AKR1B1,TNFRSF18,SLC39A10,MYRIP,S100A13,RASGRP1,CYP1B1,SOD1,TRIM8,CXXC5,ASXL1,RNF165,KLK6,PRKRA,CDK1,RHEB,GPRC5B,AGPAT2,HPSE,MADD,PRKCDBP,ADIPOR1,PSMC1,RRAGD,PRKAA2,LASP1,BMF,SERPINE2,RASA2,PSMD7,CALM3,SORBS3,ANO1,IL18R1,DUSP5,BMP2,IGF1R,CA2,KCNN4,PAK2,MDFIC,NPTN,C10orf54,WNT3A,ZRANB1,PSMA5,MDFI,PDE5A,EGFR,GNAS,MAPKAPK2,INSR,CSF1,NLRC5,JAK3,TOB1,RNF146,DRD1,AVPI1,SORBS1,IL15,PSME2,TP53,P2RX7,ERBB2,RASGRP3,EMP2,BCAP31,PDGFA,SRPX,SMO,CDH3,DIXDC1,F2R,DVL2,FRS3,CTH,SULF2,MAP3K3,PPIF,SIRT1,TIMP2,BAG4,AKT1,S100A4,CD40,MAP3K6,PTGS2,PTPRJ,PSMD3,SECTM1,CANT1,IRF7,SPTBN5,ARHGAP4,PINK1,CD63,ADGRG1,TAB3,TSPAN15,ARHGEF7,PSMD10,GDF15,TGFBR1,JAG2,PPP2R3A,KIF5B,ADORA1,BMP7,ZDHHC13,BUB1,IQGAP3,SYK,CAMK2G,P2RX4,HES1,RHOA,RAB3B,ADAM17,PSMB4,WNT10B,PLAUR,ASPM,RC3H2,LITAF,MAPK8IP1,BCL10,CD8A,BANK1,TWSG1,FGF18,E2F1,ARRB1,PKD2,NDFIP1,L1CAM |
| 4.426e-08 | -16.93 | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | 191 | 57 | 17758 | 2588 |
SORT1,CCDC109B,PARP12,ADD1,IL15,TSPAN15,IQGAP1,TAP1,GMPR,NOTUM,FAM198B,SEPT4,DDR1,FAM46C,SRPX2,BEX2,ANO1,NRP2,DAPK2,CDKN2C,PDGFA,RALGPS2,RDH14,TPST1,TMEM143,BRI3,RFX5,FAIM,PTPRE,DDX59,EPHX1,EPB41L5,PPIF,PLEKHA6,FBLN5,SPATA13,MRPS35,EPHA1,CMTM7,HLF,H1F0,NR1D2,PPP2R4,SLC4A3,PLXND1,EFNA1,NUP37,ICOSLG,PLIN3,PER3,GLCCI1,IFIH1,SERPINB1,CAPN1,JARID2,MAPK12,ABCG1 |
| 4.426e-08 | -16.93 | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | 191 | 57 | 17758 | 2588 |
RMND5A,ELK4,FBLIM1,NDRG1,RASA2,HDAC11,CCM2,SELL,IL18,IL27RA,SYTL4,DNER,FLT3,IL18R1,LTBP3,DNAJB9,RASSF8,SESN3,SCNN1A,RPS6KA2,CA2,FAM160A2,FAM13B,SLC44A1,N4BP3,PIK3CA,BCL6,FAM102A,TNFRSF18,MDFIC,KLF9,ECE1,ERBB3,MYLIP,SPRY2,C9orf72,NR3C1,USP18,KIF1C,TANC1,KCTD2,STK17B,ULK2,RAB2B,IRS2,MMP15,EPN3,HLA-B,GPRC5B,NR1D2,HOXA9,WFS1,PKD2,RELL1,GAB1,ABCA1,JARID2 |
| 5.069e-08 | -16.80 | KANG_DOXORUBICIN_RESISTANCE_UP | MSigDB lists | KANG_DOXORUBICIN_RESISTANCE_UP | 52 | 24 | 17758 | 2588 |
HMMR,PLK1,CENPA,ZWINT,HJURP,NQO1,FOXM1,ASPM,PBK,CDC20,CDCA8,WHSC1,NUSAP1,BARD1,CDK1,FANCI,TOP2A,FOSB,PRC1,PLK4,AURKA,BUB1,NCAPG2,ABCC1 |
| 5.142e-08 | -16.78 | BENPORATH_PROLIFERATION | MSigDB lists | BENPORATH_PROLIFERATION | 137 | 45 | 17758 | 2588 |
S100A11,PTTG1,NDC80,RACGAP1,NUF2,GPSM2,CENPN,LBR,NCS1,MAGOHB,TOP2A,APOBEC3B,PCNA,PDCD10,UBE2T,RANBP1,PRC1,NEK2,MSH2,CKS1B,BUB1,CKS2,NFE2L3,CENPA,PSMB4,LGALS8,ASPM,PBK,MYBL2,PKMYT1,ANLN,H2AFV,SLC25A5,FANCE,CDK1,CSNK1G1,CDCA5,NMI,FAM3C,AURKA,KPNA2,CENPE,TMEM14A,CCNB2,RRAGD |
| 5.254e-08 | -16.76 | regulation of cellular protein metabolic process | biological process | GO:0032268 | 2389 | 445 | 16441 | 2455 |
TXN,PPP4R4,ACVR1,SSH1,IBTK,GRIK2,TRIM5,DNAJC3,RET,XIAP,FBXO2,CUL1,NRG2,GATA3,PSME1,IL18,CCNB1,SEPT4,SNX9,CARD10,RIC1,PHF1,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,CTGF,ZFP36,RGS3,IL31RA,PIK3CA,CRY2,PPP1CA,NEK4,VPS11,TNIP1,ACVR1C,PBK,CASP9,SPRTN,AGO4,PRKAR2B,F12,RNF19B,POR,PIAS3,ENPP1,PLCG1,CAMK2N2,ANKRD6,PLK2,LIMK1,TBX1,TRAF3IP1,PPP2R4,NOD2,MAP3K11,SERPINB6,EIF4EBP2,SERPINI1,SPRY4,LSM14B,HSPB1,F2RL1,GAB1,CDKN1C,NUAK1,SOX9,PRKAA1,RAB23,SH3RF2,MECOM,TFAP4,CALR,RAC2,CYR61,PAIP2B,FBXO7,DAPK1,MAP3K9,SORL1,USP1,USP38,MYDGF,NCAM1,MYLIP,PPP6R1,SOCS5,MMD,MFI2,MAPKAPK3,CALM1,PYM1,EPHA1,ILK,CYFIP2,KDM3A,PSMA4,RASA1,FAS,FNTA,PRKAG2,HTT,SEMA4D,PELI2,FAM83D,AURKA,STK39,EFNA1,GDF11,MAP3K5,SERPINB1,RPS6KA3,XDH,SPRED1,DLGAP5,RPS6KA1,CAST,IQGAP1,PTTG1,PRKACA,FLT3,CCND1,CD46,APLP2,ST5,CCNA2,RALB,DACT1,CDKN1B,DAB2IP,PDE4D,OSBPL7,DLG3,RASGEF1A,CDKN2D,CAMSAP3,PSRC1,RIPK2,FZD4,DMTN,CDCA2,SLC11A2,PKMYT1,SNX12,FZD7,IRS2,FYN,JAK1,CCNB3,PPP2R5A,NGFRAP1,STK26,WFS1,CORO1C,WWTR1,KIAA1804,SLC27A1,NRG1,RGS14,ARNT,MAPK12,PRKAR1A,FARP1,PCOLCE,TNRC6C,NKX3-1,TAOK2,HSP90B1,TRAF2,SDC4,FLOT1,HERC5,PKN1,GSTP1,TIPRL,FGF19,ICAM1,SNTA1,DIRAS3,PDCD10,RNF128,IRAK1,CTSC,PTEN,KNDC1,GPC3,CST3,BAX,MAPK11,ERBB3,CNOT6L,MAP3K7,RAG1,GFI1,SPRY2,CRTAP,RASGRF1,PDGFC,RAPGEF2,EIF5A2,NUB1,GRIN1,FURIN,YES1,GPLD1,CDK5RAP1,TIMP3,FGFR2,ACVRL1,PRDX3,RYK,SERPINB5,GRIN2D,GPER1,CENPE,LRRK1,FZD5,CD81,CPEB2,ESPL1,USP16,JARID2,CCNC,CASP3,ST13,CNOT8,CAMKK1,EPHA4,ARFGEF1,NDRG2,NENF,VARS2,HDAC6,PDGFB,ERP29,SPTB,FANCI,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,PASK,DLG1,DUSP10,TNFRSF18,SLC39A10,RASGRP1,PLK1,SOD1,CD55,ITCH,USP18,C12orf65,EZR,CDK1,VCP,KDM4D,GPRC5B,MADD,IARS2,PRKCDBP,CAB39,PSMC1,PPP2R5D,LMTK3,PPP1R2,PPP1R12A,SERPINE2,DNAJB2,RASA2,UBASH3B,PDCL,PSMD7,CALM3,SORBS3,TEC,PHLPP1,FBLN1,DUSP5,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,FNIP1,MDFIC,BRAT1,NPTN,PIM1,WNT3A,CCDC88A,PSMA5,MDFI,USP31,HMG20B,STRADB,PDE5A,EIF2AK1,BCL2L13,RANBP9,EGFR,CDK5R1,FECH,MAPKAPK2,BCAR3,TSC1,INSR,PLPP3,CSF1,NFKBIA,DCUN1D1,JAK3,TOB1,CTBP1,IFI6,DRD1,PROM2,USP43,CCNE2,AVPI1,NF2,UPF3B,FOXM1,IL15,PSME2,CTDSPL,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PATL2,EMP2,STIL,BCAP31,SYTL2,PER2,RAD23A,PDGFA,SVBP,PPME1,KIF14,BCL6,TWIST1,APIP,EGLN3,F2R,CTDSP2,HSPA2,DVL2,UPF3A,FRS3,CKS2,CHP1,MAP3K3,SIRT1,TIMP2,BAG4,AKT1,CDC20,ACO1,DUSP4,CD40,CDC25C,MAP3K6,DAG1,C3orf33,SOCS3,DNAJC10,IDE,PTPRJ,PSMD3,STK38,EFNA5,SPTBN5,CNEP1R1,PPP2R2D,CTDSP1,ARFGEF3,PINK1,CPEB4,TAB3,DAP,SH3D19,SERPINB9,LRP4,PSMD10,TGFBR1,GDF15,TRIB2,PPP2R3A,SH2D4A,CD109,CARD8,ADORA1,BMP7,CKS1B,H2AFY,TRIM21,BRD7,BUB1,HEXIM2,IQGAP3,SYK,CAMK2G,DUSP1,HES1,ADAM17,RHOA,PSMB4,WNT10B,PLAUR,GCLC,RGCC,PRICKLE1,COL7A1,FXR2,MPV17L2,MAPK8IP1,USP6,BCL10,LEMD2,CNOT2,BANK1,CASP7,SWAP70,SERPINA1,SPINT2,FGF18,RAP2C,NMI,TADA2B,ARRB1,PPP2R3C,PKD2,NDFIP1,UBE2C,HIPK3,PKIA |
| 5.266e-08 | -16.76 | adenyl nucleotide binding | molecular function | GO:0030554 | 1501 | 296 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,PIK3CD,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,AURKB,ULK2,ENPP1,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,KIF23,MERTK,BMP2K,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,PDE11A,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,TMEM173,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,TRANK1,FICD,PDE4D,EPHB4,ACSL4,MYO5B,RIPK2,PFKFB2,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,ATP10D,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,PDXK,MLKL,MAPK12,PRKAR1A,GALK1,HSP90B1,TAOK2,ATP9A,PKN1,DNAH3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,RAPGEF2,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,ST13,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RPS6KA2,CDKL5,PAPSS1,PSMC2,PASK,ABCA2,KIF22,MYH14,DDX59,STK35,PLK1,NLRP4,MARK1,ROR1,ADRBK2,STK17B,CDK1,VCP,PI4K2B,IARS2,PIK3C2B,PSMC1,PRKAA2,LMTK3,RUNX2,BVES,PEX6,ABCG2,TEC,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,AHCY,PIM1,ABCC1,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,MAPKAPK2,INSR,PRPS2,NLRC5,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,P2RX7,ERBB2,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,DYRK3,PINK1,TOR4A,CIT,SHPRH,GNE,ERCC6L,TGFBR1,TOP2A,KIF5B,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,ABCD1,BUB1,HSPA13,SYK,MYO5A,ATP2B1,CAMK2G,P2RX4,GCLC,NADK2,RUNX3,DGKE,DDX23,SWAP70,UBE2D2,UBE2C,HIPK3,ABCG1 |
| 5.408e-08 | -16.73 | GSE2706_2H_VS_8H_R848_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_UP | 178 | 54 | 17758 | 2588 |
MAN2B2,SIGIRR,SORT1,PINK1,ATP8A1,ZCCHC24,BACE1,BLVRB,SDC4,EGR3,ICAM1,IER3,ARHGEF10L,CTSC,SLC16A6,SIVA1,FDXR,PRC1,FXYD5,ADAM15,SGK1,AHCY,TECR,ALDH3A2,TPCN1,CRTAP,EPHX1,CYP1B1,QSOX1,TIMP2,PQLC3,MPP1,CDA,PYGL,ERBB2IP,PDK3,RAB3IP,NPC2,ESYT1,CRISPLD2,SCRN2,AHRR,DUOX1,TRIM47,ALDH5A1,ACADSB,RAP2C,GEM,MAP3K5,NRGN,MAFF,CBX7,RARG,ABCG1 |
| 5.412e-08 | -16.73 | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | 192 | 57 | 17758 | 2588 |
GRN,SERPINE2,FRMD6,TSC22D3,SELL,IL27RA,HMGN3,SYTL4,CAMK1D,ITPR2,BAIAP3,GPSM2,PHLPP1,DHRS3,SNX9,LTBP3,SYTL2,TMEM63A,CDKN2C,RPS6KA2,IL6ST,DDHD2,BCL6,MDFIC,TNFRSF18,MXD3,KLF9,EPB41L4B,HLA-C,ERBB3,RCAN3,SUN2,PQLC3,LGALS8,PARD3B,MPP1,PCBP3,FOXJ2,TEP1,CALCRL,RAB38,ATP1B1,TANC1,ALCAM,CASP4,HLA-B,SCARB2,GPRC5B,HOXA9,CSGALNACT1,SERPINI1,ANXA9,RELL1,RBM43,ISOC1,ABCA1,IRF1 |
| 5.412e-08 | -16.73 | GSE7852_THYMUS_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TCONV_DN | 192 | 57 | 17758 | 2588 |
ILDR1,INPPL1,FARP1,DYRK3,RUNX2,KIAA1462,CD82,PTTG1,PLD2,BAIAP3,NOTCH2,PHLDA1,IL18R1,CARD10,BMP2K,HLA-A,DNAJB9,ZNF212,PLS3,IER3,APOBEC3B,RCN1,BTG3,ITGB8,RPL39,KCNK5,FOSB,RUNDC3B,DAPK1,MDFIC,TAGLN2,TSPAN1,F2R,TMBIM1,MBP,PTPN9,PTGER4,LITAF,PYGL,RUNX3,IGSF8,YES1,STX3,DGKE,FRMD4B,ENPP1,KLF12,NR1D2,LRIG1,NR4A3,NFKBIZ,RELL1,AKNA,TTC39C,TMEM159,MAFF,XDH |
| 5.425e-08 | -16.73 | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | 235 | 66 | 17758 | 2588 |
IL15RA,TRIP10,S100A11,IQGAP1,DGKA,DDR1,LTBP3,IER3,ATP6V0B,CTGF,RALB,DPYSL2,LMO4,PAPSS1,DNM2,TAX1BP3,LGMN,S100A13,TUBA4A,CYP1B1,TIMP2,COL6A2,CDC20,ARHGDIB,PKMYT1,ITPR3,LHFPL2,LCP1,STK38,PPP1CB,KLF5,TRAF5,GRN,ASAH1,PKN1,CRABP2,GSTP1,EFNB1,DUSP5,LGALS3BP,M6PR,GNS,CTSC,CYR61,PPP4R1,COL6A1,ACTA2,ADAM15,QSOX1,RHOA,PLAUR,CRIP2,LITAF,NPC2,BLVRA,POLD3,STX3,MAP1B,CD8A,RAB31,PKD2,LTBP2,ATP1B3,GEM,ARPC2,IRF1 |
| 5.433e-08 | -16.73 | cell junction | cellular component | GO:0030054 | 1147 | 233 | 17570 | 2579 |
DOC2A,ILDR1,KIAA1462,ADD1,AGRN,HSPG2,GRIK2,FAM129B,EPHA4,F11R,LGI3,MPP5,PJA2,SDC1,SLC9A3R2,PICK1,NCS1,SH3KBP1,TP73,EPCAM,ZYX,CTNNB1,P4HB,CABP1,DLG1,DNM2,AKR1B1,CLDN4,IRF2,POF1B,KIF22,CTTN,TLN2,PACSIN1,TIAM1,SMAGP,KRT80,LAP3,SNTB2,EZR,TNS1,SLC17A5,LCP1,TNS4,TRIM9,PLCG1,MPRIP,GRID2IP,DNM1L,KCNK1,LIMK1,MYLK,CTNND1,SPRY4,ARF6,HSPB1,LZTS1,CAPN1,DDX58,CD99,LASP1,SCN5A,MRC2,FRMD4A,PPP1R12A,BVES,ITGA6,CALB2,KIF23,SORBS3,TEC,NCKAP1,SSX2IP,CORO1B,CALR,FLII,TNS3,RAC2,VASP,ITGA3,ZNRF2,RIMS3,FLRT3,TBCD,PRKCI,CADPS2,PANX2,PIKFYVE,RIMS2,EPB41L5,GID8,DDB2,PCDH1,PARD3B,SHARPIN,FHL2,FBXO8,SCRIB,VEZT,CYFIP2,ILK,STEAP1,RHOB,EGFR,DCP2,STX3,RASGRP2,SCARB2,GABRD,TJP3,COL13A1,PVRL2,PLPP3,ITGA7,ARPC2,SHROOM2,AFAP1,RUSC1,CSRP2,LMO7,SORBS1,NF2,GRHL2,IQGAP1,NDRG1,P2RX7,PKP2,KCTD12,BCL2L1,MICALL2,PRR7,GNB2,CCND1,CD46,NOV,CDH1,DACT1,CDH3,DIXDC1,EPB41L4B,SCN2A,DLG3,FLOT2,CHP1,CAMSAP3,AKT1,FZD4,PTPRU,SYNE2,UTRN,CLSTN1,SYP,ATP1B1,ERBB2IP,GTF2A2,TANC1,ALCAM,DAG1,ATP1A1,PTPRJ,JAK1,SHROOM3,PTK7,CORO1C,SIPA1L1,TRIOBP,PPP1CB,PRIMA1,RGS14,RPL22,FBLIM1,FARP1,PACSIN2,HSP90B1,MPZL1,ARHGEF7,FRMD6,EPS8,SDC4,FLOT1,GABRG2,PDIA3,TGFBR1,SRPX2,ICAM1,ITGA2B,RND1,SNTA1,CAPN2,ADD3,IGSF9,CDK16,ANKS1B,CD9,ADAM15,IQGAP3,PVRL4,DLGAP1,P2RX4,AMOTL2,DCAF6,ADAM17,RHOA,CASK,CRB3,FMN1,RAPGEF2,PLAUR,PIK3R1,GRIN1,PLEKHA7,VAMP3,YES1,SNTB1,AIF1L,BCAR1,MAP1B,ARHGAP24,RPL12,RND3,SYT7,RAP2C,GRIN2D,PKD2,ITGAV,GPER1,FHL1,HMGA1,FZD5,CD81,L1CAM,OCLN,SNPH |
| 5.700e-08 | -16.68 | hepatocellular_carcinoma | COSMIC cancer mutations | hepatocellular_carcinoma | 15590 | 2347 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,SYP,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,SEMA3A,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,PINK1,CDH22,TAB3,GNAL,MCTP2,CDCA8,GTF3A,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FGF19,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,PARP14,MAN1A2,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,SHOX2,CYBRD1,UNKL,AGRN,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,MCTP1,CITED4,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,NF2,UGP2,DGKA,CCDC68,ERBB2,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,RUSC2,DAP,GNE,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,IGDCC4,MLEC,IFITM3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,TMC5,NETO2,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,PPP4R4,ACVR1,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,CDK17,ADO,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,ZNF84,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,GPR180,APOBEC3H,PNPLA5,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,VAMP3,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,SZRD1,TMCC2,SEC61B,COL6A2,PFKFB2,GIGYF1,EBF2,GABARAPL1,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,SPTB,FANCI,TFAP2E,SUSD2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERCC6L,HMGN3,GDF15,LBR,AIP,IL22RA1,VPS26A,PARM1,SH2D4A,FZD6,NRP2,CD109,C16orf74,ALPP,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,WEE1,ARHGAP42,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,FYN,PPP2R5A,STAT1,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,MIIP,PSMC1,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,PSME2,SLC2A8,GMPR,MORC4,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,MPV17L2,MAP1B,KLHL2,HLA-B,HNRNPH2,PRCP,TADA2B,HOXB13,GEM,LRRC57 |
| 5.700e-08 | -16.68 | liver-carcinoma-hepatocellular_carcinoma | COSMIC cancer mutations | liver-carcinoma-hepatocellular_carcinoma | 15590 | 2347 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,SYP,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,SEMA3A,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,PINK1,CDH22,TAB3,GNAL,MCTP2,CDCA8,GTF3A,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,HAPLN3,EPS8,EFHD2,HERC5,PLD2,FGF19,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,RDH14,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,PARP14,MAN1A2,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,SHOX2,CYBRD1,UNKL,AGRN,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,MCTP1,CITED4,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,NF2,UGP2,DGKA,CCDC68,ERBB2,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,S100A4,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,RUSC2,DAP,GNE,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,IGDCC4,MLEC,IFITM3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,TMC5,NETO2,FAM117A,PPP2R3C,TBC1D4,NDFIP1,DIS3L,PPP4R4,ACVR1,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,CDK17,ADO,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,ZNF84,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,GPR180,APOBEC3H,PNPLA5,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,FURIN,VAMP3,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,ARF4,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,ULBP2,DGKG,MYLIP,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,RHBDL3,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,SZRD1,TMCC2,SEC61B,COL6A2,PFKFB2,GIGYF1,EBF2,GABARAPL1,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,SPTB,FANCI,TFAP2E,SUSD2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,HES2,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERCC6L,HMGN3,GDF15,LBR,AIP,IL22RA1,VPS26A,PARM1,SH2D4A,FZD6,NRP2,CD109,C16orf74,ALPP,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,MATN2,C1orf21,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,GPR107,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,WEE1,ARHGAP42,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,PCNA,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,FYN,PPP2R5A,STAT1,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,AMMECR1,CCDC69,SERPINB5,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,MIIP,PSMC1,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,ZNF692,RFX5,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,PSME2,SLC2A8,GMPR,MORC4,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,MPV17L2,MAP1B,KLHL2,HLA-B,HNRNPH2,PRCP,TADA2B,HOXB13,GEM,LRRC57 |
| 5.818e-08 | -16.66 | LEF1_UP.V1_DN | MSigDB lists | LEF1_UP.V1_DN | 183 | 55 | 17758 | 2588 |
DDX58,PRSS8,NUDT6,PLSCR4,PAPSS2,ATP8A1,GALNT12,CYP2J2,IL18,PDGFRL,SAMD9,HERC6,SEPP1,ELF3,IL17RB,RAC2,TNS3,AP1M2,CTGF,AIM1,OPN3,DAPK1,SORL1,MDFIC,DIXDC1,LIMCH1,MXD3,OAS3,MARCH2,RAB27B,TSPAN1,MYRIP,CPE,ERAP2,CYP1B1,CYP26B1,PDGFC,STAT4,USP18,SH3BGRL,TMEM144,ATP1B1,ALCAM,DPYSL3,PITX2,PIAS3,ALDH5A1,RBM47,GDE1,PLOD2,RHOBTB2,HOXB13,TMEM14A,FOXA1,FAM134B |
| 6.019e-08 | -16.63 | MODULE_3 | MSigDB lists | MODULE_3 | 382 | 95 | 17758 | 2588 |
DLGAP5,HSPG2,EPAS1,NQO1,S100A11,FOXM1,IQGAP1,SUZ12,PTTG1,CCNB1,IER3,PLS3,CCND1,APOBEC3B,PDGFA,RCN1,ZYX,BTG3,PCNA,CCNA2,SRPX,PSMC2,DNM2,VAT1,RGS5,F2R,CKS2,PLK1,SEC23A,CD55,CENPA,CDC20,ARHGDIB,AURKB,LOXL2,CCNF,MCFD2,ITPR3,ALCAM,CDK1,CASP4,DPYSL3,MDK,PGF,TRAM2,PLK2,WWTR1,IARS2,PLXND1,MAFF,GRN,ANXA3,ITGA6,PSMD7,GDF15,TOP2A,RAC2,FLII,IRAK1,CYR61,CTSC,CALD1,PPP4R1,UBE2J1,SGK1,SRP54,IGFBP2,CITED2,TMX1,SMC4,QSOX1,FADS2,ZWINT,PRSS23,CTNNAL1,PLAUR,FHL2,MYBL2,CALCRL,EMP3,GGH,MEST,KIF11,ZDHHC3,PSMA4,STEAP1,SWAP70,UAP1,PLOD2,RND3,LTBP2,UBE2C,CCNB2,PKIA,ACOT7 |
| 6.086e-08 | -16.61 | BURTON_ADIPOGENESIS_PEAK_AT_24HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_24HR | 42 | 21 | 17758 | 2588 |
HMMR,GALK1,KIF20A,CDC20,PTTG1,RACGAP1,NUSAP1,ISYNA1,AURKB,CCNB1,ANLN,CDC25C,CDK1,TOP2A,CCNA2,PRC1,KIF22,KPNA2,BUB1,UBE2C,MELK |
| 6.150e-08 | -16.60 | MODULE_18 | MSigDB lists | MODULE_18 | 440 | 106 | 17758 | 2588 |
TRIM2,DLGAP5,NQO1,EPAS1,FOXM1,S100A11,PTTG1,C5orf30,NRG2,CCNB1,SDC1,EMP2,CARD10,IER3,APOBEC3B,CDKN2C,BTG3,PCNA,CCNA2,SRPX,ALDH1A3,PSMC2,VAT1,IFIT1,CKS2,PLK1,LAMP2,SEC23A,SGCE,TIMP2,CENPA,PFKFB2,S100A4,PTPN9,CDYL,CDC20,CDA,HTATIP2,AURKB,PKMYT1,DUSP4,ICMT,ITPR3,CCNF,CDK1,TRAM2,ATP1A1,AGPAT2,PLK2,TBX1,WWTR1,IARS2,BMP1,GCLM,COL9A3,PCOLCE,CDKN1C,ITGA6,EPS8,ETV5,GDF15,TRIB2,DHRS3,HOXB2,ITGA2B,PDIA4,CKAP5,M6PR,TOP2A,SPP1,RAC2,ITGA3,IRAK1,CTSC,CD22,FDXR,TFAP2A,AHCY,ERBB3,MOXD1,MSH6,GPR161,TMX1,IGSF3,PIGC,TGIF1,ZWINT,PRSS23,PLSCR1,LPGAT1,FHL2,EMP3,TCF7,GGH,KIF11,PSMA4,CDK5R1,TIMP3,RND3,PLOD2,E2F1,SHROOM2,UBE2C,ESPL1,ACOT7,JARID2 |
| 6.217e-08 | -16.59 | GSE7852_LN_VS_THYMUS_TCONV_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_DN | 188 | 56 | 17758 | 2588 |
EXPH5,LZTFL1,TXN,ENO2,DEPDC1,FRMD6,IQGAP1,NDRG1,HAL,FAM102B,KIF2C,ITPR2,ZNF212,ZDHHC21,IL17RB,TOP2A,RB1,PCNA,CTSC,CASC4,FUT8,PRC1,CKS1B,ALDH7A1,NTN4,PLK1,P2RX4,CXXC5,CENPA,FIGNL1,PBK,CDC20,CCDC34,PRICKLE1,PDE5A,PRKAR2B,NUSAP1,CCNF,PRKRA,PTGFRN,CDK1,STX3,PRIM1,PTPRF,ALDH5A1,NGFRAP1,ABHD12,CDCA5,C1orf21,CENPE,NCAPG2,UBE2C,ESPL1,E2F8,MELK,PRKAR1A |
| 6.217e-08 | -16.59 | GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN | 188 | 56 | 17758 | 2588 |
DDX58,PARP12,PARP14,TRIM5,PSME2,TAP1,GMPR,KIF23,HERC5,SAMD9,FBXO6,HERC6,LGALS3BP,BMP2K,DTX3L,SP100,PIK3AP1,EFR3A,ZNRF2,MSH2,IFIT1,OAS3,PSMA5,LAMP3,PARP9,MX1,ZWINT,PLSCR1,IFITM3,LAP3,OSTM1,PBK,USP18,C1GALT1C1,BLVRA,IFIT3,PSMA4,TMEM50B,PI4K2B,SCARB2,CASP7,C19orf66,TRIM69,NAT1,NMI,SECTM1,STAT1,TDRD7,AURKA,PPP2R3C,IRF7,MRPS28,CMPK2,IFIH1,SLC31A2,IFI6 |
| 6.286e-08 | -16.58 | ENK_UV_RESPONSE_EPIDERMIS_DN | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_DN | 499 | 117 | 17758 | 2588 |
LZTFL1,HECA,ST14,HEBP1,NDRG1,GATA3,TESK2,DHX8,EGR3,SLC20A1,PHLDA1,ERP29,EMP2,CYP39A1,MXD1,CCND1,TGFBR3,HSF2,RPS6KA2,TACC2,KLF3,FOSB,DLG1,DUSP10,CDH3,TECR,F2R,SULT2B1,SIRT1,TIMP2,CD55,S100A4,SH3BGRL,UTRN,PTGER4,EZR,ERBB2IP,STK17B,FZD7,ABR,IRS2,PTGS2,FYN,HLF,AREG,KCNK1,NGFRAP1,CORO1C,SH3GLB2,NOD2,KLF11,ANXA9,HSPB1,F2RL1,RTN3,CBX4,KLF2,PACSIN2,LGALS3,CDKN1C,CYP2J2,DNAJB2,ARL4C,ASAH1,PBX3,RACGAP1,SEPP1,S100A2,NEO1,CTNNBIP1,FRY,FJX1,PRC1,OPN3,PIM1,SPRY2,ATP2B1,PDGFC,ALDH2,B3GNT2,PRSS23,TESK1,GUSB,PLAUR,FHL2,DIAPH2,COL7A1,NFIB,RHOB,CD83,BCL10,MAPKAPK2,PTPRF,TMEM50B,DDAH1,SLCO4A1,INSR,UAP1,PVRL2,SEMA4D,FGFR2,DCK,PELI2,DBI,MATN2,C1orf21,FAM117A,NR4A2,FHL1,ITGAV,PLD1,PER3,HOOK1,RPS6KA3,PKIA,JARID2,EGLN1 |
| 6.604e-08 | -16.53 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_UP | 193 | 57 | 17758 | 2588 |
CMAS,CDS2,ADD1,LGALS3,S100A11,GNPDA1,CAST,DAP,ARL4C,FLOT1,SELL,FTH1,CRABP2,OAT,IL18R1,FGF19,XPR1,PLS3,RAC2,GNB5,IL6ST,TWIST1,TACSTD2,ALDH7A1,AHCY,TAGLN2,CTSD,S100A6,GCNT1,P2RX4,SUN2,S100A4,DSTN,CBX6,FURIN,ARHGDIB,NKAIN1,B3GALNT2,ALCAM,CYB5A,IRX3,GABARAPL1,IL1R1,ONECUT1,RPL12,CDCA7L,SERPINB5,AURKA,GEM,TMEM159,JAK3,E2F8,AHR,PPP2R5D,KLF7,JARID2,EHD1 |
| 6.613e-08 | -16.53 | GNF2_RRM1 | MSigDB lists | GNF2_RRM1 | 87 | 33 | 17758 | 2588 |
DLGAP5,FOXM1,NDC80,CDCA8,RACGAP1,FANCI,TOP2A,PCNA,CCNA2,KIF14,PRC1,PLK4,MSH2,SMC4,METAP2,CKS2,HMMR,PCCB,ZWINT,ASPM,CDC20,NUSAP1,AURKB,KIF11,CDK1,PRIM1,AURKA,CENPE,NUP37,CCNB2,UBE2C,E2F8,MELK |
| 6.748e-08 | -16.51 | ONDER_CDH1_TARGETS_2_UP | MSigDB lists | ONDER_CDH1_TARGETS_2_UP | 246 | 68 | 17758 | 2588 |
MYL9,CCNE2,LTBP1,REPS2,TSC22D3,LMCD1,PDGFRL,SLC7A2,PLA2G16,CHST2,CDKN2C,TGFBR3,RPS6KA2,CTGF,MITF,AOX1,SRR,TWIST1,MYBL1,CYP1B1,DOCK4,COL6A2,SEPT6,PTGER4,KDELR3,ROR1,DPYSL3,TRAM2,ENPP1,WIPI1,LRIG1,RCAN2,STARD13,BIN1,PCOLCE,ENO2,ALDH6A1,ZCCHC24,EPS8,FLOT1,FBLN1,ARHGEF40,CCDC92,MLPH,COL6A1,ACTA2,H2AFY,KANK2,KLF9,MOXD1,CITED2,SNED1,DUSP1,TRAK2,FBLN5,CRIP2,CYFIP2,LEPR,MAP1B,MAGED2,DDAH1,FAT4,PLOD2,ITGA7,PPM1H,LTBP2,SHROOM2,CYBRD1 |
| 6.772e-08 | -16.51 | adenyl ribonucleotide binding | molecular function | GO:0032559 | 1493 | 294 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,PIK3CD,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,AURKB,ULK2,ENPP1,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,KIF23,MERTK,BMP2K,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,PDE11A,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,TMEM173,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,TRANK1,FICD,PDE4D,EPHB4,ACSL4,MYO5B,RIPK2,PFKFB2,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,ATP10D,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,PDXK,MLKL,MAPK12,PRKAR1A,GALK1,HSP90B1,TAOK2,ATP9A,PKN1,DNAH3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,RAPGEF2,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RPS6KA2,CDKL5,PSMC2,PAPSS1,PASK,ABCA2,KIF22,MYH14,DDX59,STK35,PLK1,NLRP4,MARK1,ROR1,ADRBK2,STK17B,CDK1,VCP,PI4K2B,IARS2,PIK3C2B,PSMC1,PRKAA2,LMTK3,RUNX2,BVES,PEX6,ABCG2,TEC,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,PIM1,ABCC1,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,MAPKAPK2,INSR,PRPS2,NLRC5,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,P2RX7,ERBB2,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,DYRK3,PINK1,TOR4A,SHPRH,CIT,GNE,ERCC6L,TGFBR1,TOP2A,KIF5B,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,ABCD1,BUB1,HSPA13,SYK,MYO5A,ATP2B1,CAMK2G,P2RX4,GCLC,NADK2,RUNX3,DGKE,DDX23,SWAP70,UBE2D2,UBE2C,HIPK3,ABCG1 |
| 6.851e-08 | -16.50 | HAMAI_APOPTOSIS_VIA_TRAIL_UP | MSigDB lists | HAMAI_APOPTOSIS_VIA_TRAIL_UP | 554 | 127 | 17758 | 2588 |
ARHGAP11A,TRIM2,ARMCX3,CEP70,PAPSS2,TRIM24,DLGAP5,RALBP1,CAST,SUZ12,DNAJC3,CUL4B,NDC80,ARFGEF1,DNAJB11,PDGFRL,TRAPPC8,NUF2,ITPR2,PJA2,DPP8,NUDT12,MNS1,KTN1,PLS3,ZFYVE16,CDH1,FAM46A,KIF14,MITF,PIK3CA,SNX16,WBP4,SNX10,UPF3A,METAP2,SULF2,ATL1,SMARCA2,CD55,LGALS8,OSTM1,SH3BGRL,PBK,BNIP3L,NUSAP1,RAD17,ATP1B1,ANLN,OPTN,NIN,SOCS3,PI4K2B,WDR11,DNM1L,STAT1,SLC27A3,ST3GAL1,NRGN,MYL12B,FAM134B,PCSK5,RECQL,COL9A3,GOLIM4,DEPDC1,ITGA6,ASAH1,KIF23,CTSZ,NUCB2,VPS26A,PPP2R3A,SCML1,KIF5B,B3GALNT1,SPP1,SNX13,PDCD10,ADD3,PTEN,CALD1,BHLHE41,MGAT4A,BMP7,FAM13B,KIAA0319,GTF2F2,MSH2,SORL1,WWP1,USP1,KNTC1,AK3,ZMYM1,RPGR,MYO5A,SMC4,HMMR,GCC2,PHF20L1,ALDH2,FBLN5,MMD,CTNNAL1,ASPM,VEZT,GGH,KIF20B,NPDC1,KIF11,NFIB,PSMA4,AP1AR,NMI,MATN2,ITPR1,DCUN1D1,TCEAL4,ACADM,CENPE,ITGAV,ETAA1,IFIH1,GOLGB1,RAD21,DOCK9 |
| 7.158e-08 | -16.45 | positive regulation of protein metabolic process | biological process | GO:0051247 | 1523 | 300 | 16441 | 2455 |
TXN,ACVR1,TRIM5,DNAJC3,RET,XIAP,CUL1,NRG2,PSME1,IL18,CCNB1,SEPT4,SNX9,BARD1,CARD10,PHF1,GRM5,TP73,CALM2,PAK6,PSMD1,CTGF,IL31RA,PIK3CA,TIPARP,NEK4,VPS11,ACVR1C,CASP9,SPRTN,PRKAR2B,F12,RNF19B,PIAS3,PLCG1,ANKRD6,PLK2,TBX1,PPP2R4,NKD1,NOD2,MAP3K11,HSPB1,F2RL1,GAB1,KLF2,GGA1,SOX9,PRKAA1,TFAP4,CYR61,DAPK1,MAP3K9,SORL1,MYDGF,NCAM1,MAPK7,MYLIP,SOCS5,MMD,MFI2,MAPKAPK3,CALM1,PYM1,CYFIP2,ILK,PSMA4,RASA1,FAS,FNTA,PRKAG2,SEMA4D,PELI2,AURKA,STK39,EFNA1,GDF11,MAP3K5,XDH,IRF1,SPRED1,DLGAP5,IQGAP1,PRKACA,FLT3,APC2,CCND1,ST5,RALB,DACT1,CDKN1B,DAB2IP,OSBPL7,RASGEF1A,PSRC1,RIPK2,FZD4,CDCA2,PRKCQ,SLC11A2,PXYLP1,FZD7,IRS2,FYN,JAK1,PPP2R5A,NGFRAP1,STK26,WFS1,KIAA1804,SLC27A1,NRG1,ARNT,MAPK12,PRKAR1A,PCOLCE,TAOK2,NKX3-1,TRAF2,SDC4,FLOT1,PKN1,FGF19,ICAM1,PDCD10,IRAK1,RNF128,CTSC,PTEN,KNDC1,GPC3,BAX,MAPK11,ERBB3,MAP3K7,SPRY2,RASGRF1,PDGFC,RAPGEF2,NUB1,EIF5A2,GRIN1,FURIN,YES1,GPLD1,FGFR2,ACVRL1,RYK,GRIN2D,GPER1,CENPE,LRRK1,FZD5,CD81,ESPL1,USP16,JARID2,CCNC,CASP3,CAMKK1,CUL4B,EPHA4,ARFGEF1,NENF,ERP29,PDGFB,SPTB,FANCI,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,PASK,DLG1,TNFRSF18,SLC39A10,RASGRP1,PLK1,SOD1,ITCH,EZR,CDK1,VCP,GPRC5B,MADD,PRKCDBP,CAB39,PSMC1,PPP1R12A,RASA2,DNAJB2,ASB9,PSMD7,CALM3,SORBS3,TEC,FBLN1,DUSP5,BMP2,RB1,IGF1R,PAK2,FNIP1,BRAT1,MDFIC,NPTN,PIM1,WNT3A,PSMA5,CCDC88A,MDFI,STRADB,PDE5A,BCL2L13,EGFR,CDK5R1,BCAR3,MAPKAPK2,INSR,PLPP3,CSF1,NFKBIA,DCUN1D1,JAK3,CTBP1,PROM2,AVPI1,UPF3B,IL15,PSME2,TP53,P2RX7,ERBB2,RASGRP3,CCNL1,STIL,EMP2,BCAP31,IER3,PDGFA,KIF14,BCL6,EGLN3,F2R,HSPA2,DVL2,UPF3A,FRS3,CHP1,MAP3K3,SOAT1,SIRT1,BAG4,TIMP2,AKT1,CDC20,CD40,MAP3K6,PSMD3,SPTBN5,EFNA5,CNEP1R1,PINK1,TAB3,SH3D19,DAP,PSMD10,GDF15,TGFBR1,TRIB2,PPP2R3A,CARD8,ADORA1,BMP7,BRD7,IQGAP3,SYK,CAMK2G,HES1,RHOA,ADAM17,PSMB4,PLAUR,GCLC,RGCC,PRICKLE1,MPV17L2,BCL10,CASP7,BANK1,RAP2C,FGF18,NMI,TADA2B,ARRB1,PKD2,PPP2R3C,UBE2C,NDFIP1 |
| 7.294e-08 | -16.43 | SMID_BREAST_CANCER_BASAL_UP | MSigDB lists | SMID_BREAST_CANCER_BASAL_UP | 615 | 138 | 17758 | 2588 |
LTBP1,TRIM2,KLK10,UGT8,MCOLN3,TAP1,NDC80,NDRG2,CENPN,BTG3,CTGF,ELF5,ATP13A3,MYBL1,LAMP3,ING1,CENPA,PBK,CDYL,KLK6,CDK1,PLEKHB1,PLCH1,HPSE,GPRC5B,MAP2,HOXA9,MYLK,APBA2,DLAT,RRAGD,RMND5A,ITGA6,RASA2,CALB2,SOX9,RAB23,C6orf106,GPSM2,S100A2,CALR,SPP1,KCNN4,NEK2,FXYD5,NCAM1,GPR161,CCDC88A,MDFI,CYP26B1,KLK5,MYBL2,WHSC1,NFIB,EGFR,SLC2A6,AGBL5,KLK7,CCNB2,IFIH1,CSRP2,RAD21,PLA2G4A,PAX6,DLGAP5,FOXM1,NDRG1,GALNT12,PTTG1,TP53,SOD2,RGS20,IRX4,MRAS,IL27RA,PHLDA1,CYP39A1,APOBEC3B,MUC16,CCNA2,ARTN,LMO4,CDH3,TMCC2,CAPN6,CYB5R2,S100A4,CDC20,NUSAP1,FZD7,NFIX,SOCS3,PTGS2,DUOX1,PTK7,WWTR1,KLF5,PDXK,ARNT,ANXA3,COL9A3,CKAP2,JRKL,CDCA8,CDCA3,ARL4C,NES,GSTP1,LBR,ICAM1,ITGB8,SLC27A6,KCNK5,CALD1,BUB1,TAGLN2,ITM2C,MSH6,S100A6,NFE2L3,ADAM17,PLSCR1,ASPM,GGH,RUNX3,YES1,SNTB1,PROM1,PLOD2,RND3,SERPINB5,CLIP4,CENPE,HMGA1,SHOX2,L1CAM,ARHGEF9,MELK |
| 7.524e-08 | -16.40 | SH3_domain | interpro domains | IPR001452 | 217 | 62 | 18293 | 2672 |
BIN1,LASP1,TNK1,SORBS1,PACSIN2,TRIP10,MACC1,ARHGEF7,SH3D19,RUSC2,UBASH3B,EPS8,MPP5,SORBS3,TEC,CACNB4,SNX9,ARHGEF16,SH3KBP1,EPS8L2,SH3RF2,SH3D21,ARHGAP42,NOXA1,ARHGEF37,SNX18,MCF2L,FUT8,PLCG2,DLG1,MAP3K9,OSTF1,CTTN,PACSIN1,DLG3,NEB,DOCK4,CASK,MPP1,PIK3R1,SPATA13,YES1,DOCK5,BCAR1,MAPK8IP1,ARHGEF26,RASA1,TXK,PLCG1,ARHGEF19,FYN,TJP3,SH3BP4,SH3GLB2,KIAA1804,MPP2,MAP3K11,ARHGAP4,ARHGEF9,RUSC1,NGEF,ARHGEF4 |
| 7.862e-08 | -16.36 | enzyme regulator activity | molecular function | GO:0030234 | 904 | 192 | 16491 | 2452 |
CCNC,CASP3,FAF2,PPP4R4,IBTK,DNAJC3,ARFGEF1,XIAP,PSME1,PDGFB,ELMOD2,CDKN2C,CALM2,SIPA1L2,PCNA,RGS12,ARHGAP42,PSMD1,RABEP2,RGS3,ARL1,CABP1,PPP1R16A,PIK3CA,RGS5,RP2,RCAN3,CASP9,ARHGDIB,PRKAR2B,PIF1,PRKRA,PPP1R14C,VCP,ABR,SEC14L2,PLEKHG6,ARHGEF19,TBC1D17,CAMK2N2,GPRC5B,MADD,PPP2R4,CAB39,AGFG2,SERPINI1,SERPINB6,RAP1GAP,HSPB1,STARD13,PPP2R5D,ARAP3,PPP1R12A,SERPINE2,PPP1R2,CDKN1C,TBC1D1,RASA2,CALM3,RACGAP1,GPSM2,FBLN1,BMP2K,SH3RF2,BMP2,RAC2,NOXA1,TIMP1,RINL,OCRL,PPP4R1,FAM13B,RANBP1,TBCD,PAK2,ALS2CL,TBC1D8B,CALM1,BCL2L13,RHPN1,EGFR,RASA1,CDK5R1,MMP15,TSC1,PRKAG2,SH3BP4,ARAP1,CTSA,CABIN1,ATP1B3,SERPINB1,RPS6KA3,DMPK,CCNE2,ARHGAP11A,SPRED1,PSME2,RALBP1,RPS6KA1,CAST,IQGAP1,PTTG1,WDTC1,RGS20,TP53,RASGRP3,MGST2,CCNL1,CCND1,CD46,APLP2,ACAP2,SH3BP1,PPME1,CDKN1B,DAB2IP,CDKN2D,GM2A,EBAG9,CKS2,CHP1,TBC1D10B,DOCK4,TIMP2,AKT1,ATP1B1,SOCS3,ARHGAP35,DNAJC10,PPP2R5A,NGFRAP1,MMP17,PSMD3,SIPA1L1,RCAN2,EFNA5,NRG1,RGS14,ARHGAP4,PPP2R2D,PRKAR1A,ANXA3,GCLM,NKX3-1,PINK1,PCOLCE,DEPDC1,ARHGEF11,SERPINB9,SBF1,TRIB2,GSTP1,PPP2R3A,SYDE2,CD109,CARD8,LLGL2,PPP1R10,CTSC,GPC3,CST3,H2AFY,CKS1B,TMBIM6,ERBB3,HEXIM2,IQGAP3,SPRY2,ARAP2,RAPGEF2,PIK3R1,RGCC,FURIN,COL7A1,GRTP1,MAPK8IP1,BCL10,ARHGAP24,CDK5RAP1,RGS9,TIMP3,SERPINA1,PRDX3,SPINT2,RIN3,ARRB1,SERPINB5,ARFGAP3,TBC1D4,CPEB2,PKIA |
| 7.908e-08 | -16.35 | CYTOPLASM | MSigDB lists | CYTOPLASM | 2079 | 385 | 17758 | 2588 |
LAMP1,SSH1,AASS,MRPS15,SLC25A13,DNAJC3,KLC2,XIAP,PSME1,TGOLN2,ISOC2,CNTROB,OAT,BARD1,CHST2,SLC9A7,PICK1,CALM2,NPM2,CDKN2C,DAPK2,NAPG,STIM1,RGS3,ZFP36,RDH14,SLC46A1,STEAP2,FUT1,TUBG1,TACSTD2,ERAP2,METAP2,LAMP2,SGCE,SH3BGRL,SNTB2,UXT,TMEM98,CDA,BNIP3L,SLC17A5,ICMT,MYOM1,POR,LCP1,PLCG1,SLC25A4,DNM1L,LIMK1,ATP7B,MAP3K11,NOD2,HDAC1,SERPINB6,MRPS28,ARF6,HSPB1,F2RL1,ANXA11,FGD1,NFKBIE,CDKN1C,GGA1,STRN4,SLC25A27,NDUFA4,APBA1,ATG4A,CALR,DOPEY2,WDFY1,DNPEP,NECAB3,RANBP1,NEK2,FAM84B,STT3B,TMED2,EEF1D,TRAK2,PIGC,QSOX1,KIF20A,LPGAT1,CALM1,KIF20B,NPC2,CYFIP2,GNA11,STX3,AP1AR,NAAA,SERTAD2,FNTA,PLEKHH2,HTT,ARAP1,FGD6,MDH1,PLIN3,NDE1,EGLN1,SLC2A4,DLGAP5,NQO1,S100A11,DDIT4L,PTTG1,BCL2L1,AIFM2,KTN1,RCN1,CDH1,CDKN1B,TNPO2,PHKA2,SULT2B1,CDKN2D,GPX4,ATG4D,SEMA3B,MX1,SEC23A,SEC61B,TMEM43,COG2,AGPS,TEP1,VPS4B,COX11,HTATIP2,KIF1C,PKMYT1,ITPR3,GABARAPL1,NIN,FYN,PPP2R5A,DDOST,STX10,SLC9A6,STAT1,PDXK,ISOC1,MAPK12,GALK1,HSP90B1,BACE1,DCAF7,CCM2,PDIA3,CTSZ,NUCB2,GSTP1,PDIA4,CKAP5,FUT2,OXCT1,PTEN,CTSC,ARSG,FDXR,TUBGCP6,BAX,ECI2,TMBIM6,AK3,SGCB,ITM2C,S100A6,MED22,TMX1,FARP2,PCCB,SHMT1,PIK3R1,FURIN,RAB3IP,SNTB1,CRISPLD2,BTG1,NUCB1,LDLRAP1,CTNS,KIAA0141,ACADSB,PLOD2,PRDX3,ERAP1,ARFGAP3,ARSB,ESPL1,ACOT7,USP16,MYL9,TNK1,TRIM2,ST13,DNAJB11,MPP5,ITPR2,HDAC6,DNER,ERP29,MAP1LC3B,SPTB,ARHGEF10L,BTG3,ENTPD4,CTNNB1,TM9SF2,CNTRL,P4HB,LMAN2L,ARL1,PSMC2,ABCA2,TMEM143,DUSP10,CTTN,PXMP4,TRAM1,NEB,LAMP3,PLK1,PCGF5,SOD1,MARK1,EZR,KLK6,ARHGDIB,ERP44,MRPS18A,ROR1,PRKRA,ANLN,MRPS36,IDH1,VCP,OPTN,DZIP1L,PLCH1,AGPAT2,WIPI1,DOLPP1,MADD,SH3GLB2,KPNA2,GLA,POMT1,RAP1GAP,PCSK5,RRAGD,CD99,LASP1,USH1C,ARAP3,ZNF395,LGALS3,PEX6,ASL,PDCL,CALM3,RAB6A,PGAP1,CA2,CES2,PFKL,KIF13B,OCRL,PRKCI,PIM1,ZRANB1,MPHOSPH9,CCDC88A,KDELR1,MDFI,RGMB,PCBP3,STRADB,PDK3,CDK5R1,EGFR,GLCE,GNAS,TSC1,CDCA5,NFKBIA,CTSA,PLD1,SHROOM2,IFI6,LMO7,DYNLRB1,NF2,IL15,SOD2,PDIA5,TP53,ZMYND10,EXT2,SYTL2,CDK14,REEP1,FABP6,RPN2,MINPP1,NFKB2,LMAN1,PDIA6,F2R,SCYL3,DVL2,SOAT1,CLCN3,GCA,AKT1,ACO1,MRPS35,GLO1,ERBB2IP,TMTC2,TAPBP,PTGS2,ALDH5A1,IDE,PEX2,SECTM1,IRF7,ANXA9,SYT13,ARHGAP4,MAD2L1BP,AIFM3,ABCA1,ANXA3,PINK1,GOLIM4,PACSIN2,CD63,SERPINB9,GNE,DSE,TRIB2,AIP,DNAJB9,VPS26A,SAC3D1,HDAC9,TOP2A,KIF5B,CARD8,ADRBK1,MAGEE1,RRBP1,SLC35B4,TRIM3,BRD7,BUB1,HEXIM2,SLC35A1,RPGR,MYO5A,B3GALT6,NR3C1,AMFR,PRICKLE1,FXR2,NDRG3,BCAR1,MAPK8IP1,BCL10,USP6,TMEM50B,CASP7,NMI,SPINT2,ARRB1,PKD2,ACADM,PLOD3,CEP41,ABCG1,GOLGB1 |
| 7.942e-08 | -16.35 | protein kinase regulator activity | molecular function | GO:0019887 | 132 | 44 | 16491 | 2452 |
CCNE2,CCNC,CASP3,SPRED1,NKX3-1,CDKN1C,IBTK,IQGAP1,DNAJC3,CALM3,CCNL1,TRIB2,CALM2,CDKN2C,CCND1,RAC2,PAK2,PIK3CA,H2AFY,CKS1B,CDKN1B,HEXIM2,ERBB3,CDKN2D,SPRY2,CHP1,CKS2,CALM1,RGCC,PRKAR2B,MAPK8IP1,CDK5R1,SOCS3,CDK5RAP1,PRKAG2,CAMK2N2,GPRC5B,MADD,CAB39,EFNA5,NRG1,HSPB1,PKIA,PRKAR1A |
| 8.037e-08 | -16.34 | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | 312 | 81 | 17758 | 2588 |
PNISR,PAPSS2,SUZ12,NDRG1,TMX4,MCCC1,CACNA2D2,C5orf30,MORC4,GATA3,PKP2,EGR3,PLA2G16,APLP2,METTL7A,TACC2,IL6ST,ALDH1A3,CDKN1B,STEAP3,ARNT2,S100A13,TUBA4A,PPIF,AGPS,RNF11,C3orf52,PRKAR2B,RAB38,ASB13,IDH1,ALCAM,ULK2,PLEKHB1,OPTN,PLCH1,GPRC5B,MAOA,TLE1,ANXA9,TRAF5,COL9A3,MPZL1,ENO2,CYP2J2,DAP,MTL5,PRKAA1,CRABP2,PSIP1,MZT2A,IGF1R,TMEM62,MCF2L,AIM1,OPN3,LIMCH1,ACAD8,FAR2,MPHOSPH9,QSOX1,MICB,AK4,SPTLC2,EGFR,CYB5A,DCAF10,GALNT3,NAAA,SWAP70,FGFR2,CCDC6,WDR19,DBI,CSGALNACT1,PGRMC1,STK39,ACADM,MAP3K5,PER3,ACOT7 |
| 8.042e-08 | -16.34 | GSE7852_TREG_VS_TCONV_FAT_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_FAT_UP | 194 | 57 | 17758 | 2588 |
LZTFL1,SORBS1,PAX6,KIAA1462,NFKBIE,NDRG1,ATP8A1,ZCCHC24,ASL,IL18,TMEM170B,NCKAP1,SNX9,PHLDA1,SYTL2,M6PR,NPNT,PRICKLE3,ZFP36,OSBPL3,MITF,ATP13A3,MTMR10,FXYD5,TNFRSF18,TSPAN13,ARNT2,NEB,TMBIM1,GM2A,DUSP1,ENPP4,TGIF1,ERMP1,ADCK3,PLEKHA7,TNFAIP8L1,DUSP4,TMTC2,ALCAM,SESN1,GPLD1,CMTM7,MAPKAPK2,KDSR,SWAP70,MID1IP1,AREG,CSGALNACT1,ARRB1,SERPINB6,NFKBIZ,PLXND1,PIEZO1,ITGAV,GEM,CSRP2 |
| 8.042e-08 | -16.34 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | 194 | 57 | 17758 | 2588 |
LTBP1,SLC25A24,FAF2,GRHL2,GCAT,GATA3,B4GALT4,CDIPT,FAM46C,CENPN,RCN1,RB1,ZNF823,GRHL1,PFKL,BDH1,PPP1R16A,FUT8,PAPSS1,FAM20B,CAPG,MTMR10,KLC3,ARVCF,TNFRSF18,MAPK11,ALDH7A1,MANF,RCAN3,CITED2,CTDSP2,RASGRP1,PIGC,LONRF3,FAM133B,EAF2,GTF2A2,ZBTB7B,NDRG3,CASP4,PRDX4,DNAJC10,FYN,KCNMB4,TIMP3,ETS2,AREG,PSMD3,SLC25A40,HAGHL,CSGALNACT1,ALG2,RGS14,RAP1GAP,AHR,ZC3HC1,RRAGD |
| 8.062e-08 | -16.33 | HOELZEL_NF1_TARGETS_UP | MSigDB lists | HOELZEL_NF1_TARGETS_UP | 130 | 43 | 17758 | 2588 |
FAM89A,RBM24,LGALS3,FAM199X,GRIK2,EPS8,CYB561,GDF15,NUP62CL,PHLDA1,S100A2,PLS3,PDGFA,SESN3,FAM46A,SLC27A6,OSBPL3,DRAM1,STEAP3,GAD1,CAPN6,SEPT6,DUSP4,STK17B,FAS,GNAS,ENDOD1,CCNB3,PDLIM3,SCG2,RND3,ACVRL1,MAP2,PLK2,TSPAN18,FAM114A1,RAB31,NRG1,HS3ST3B1,RPS6KA3,FAM134B,NXT2,HS6ST3 |
| 8.220e-08 | -16.31 | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | 9663 | 1528 | 17775 | 2585 |
HECA,FAM160B1,IBTK,AK7,HEXB,RET,CCNO,BAIAP3,LACTB2,DPP8,SNX9,FAM46C,SPSB1,CARD10,LTBP3,ZNF275,GRM5,LYPD5,CDKN2C,MUC4,UBE2T,ATP13A3,DNM2,PPP1CA,TMEM37,RNF26,WBP4,TIAM1,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,CDA,KDELR3,PRKAR2B,RNF19B,PNKD,GINS4,ABR,ARF4,LCP1,PIAS3,PLCG1,MPRIP,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,RNASEL,ITPKA,HSPB1,ZNF720,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,COX6C,CCDC64B,FAM21C,TTYH3,ATG4A,MARCH8,TFAP4,FLII,SH3D21,RAC2,MEGF8,FBXO7,RANBP1,FBXL14,PCYOX1,MAP3K9,CADPS2,USP1,USP38,ALPK1,FAM84B,MAPK7,ZMYM1,MYLIP,DGKG,ULBP2,KANK3,NUP85,PHKG2,HPS3,FHL2,KIF20B,ELK1,PSMA4,GNA11,PLIN5,MAGED2,IL1R1,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,CLMN,OSCP1,GDF11,CBX5,ADAMTS16,DMPK,DOCK9,WDR63,TPRN,LFNG,CD82,PTTG1,RHBDL3,APOO,C5orf30,GRK6,MGST2,REPS1,APPBP2,RBM23,MUC16,ST5,CDH1,SH3BP1,RASGEF1A,DLG3,ZNF365,ETV4,MYT1,SNX10,MX1,SNX8,SEC61B,COL6A2,RIPK2,APOBEC3D,PTPN9,SEPT6,SAT1,SYP,DNAJB14,TANC1,ZNF618,SNX12,TRIM7,GIGYF1,NFIX,SPIN3,CCNB3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,FAM149A,DMWD,MAPK12,HSP90B1,CKAP2,GCAT,TRAF2,BIK,OSGIN2,BTN3A1,CTSZ,ZNF219,IFT27,SLC25A43,NFAT5,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,SLC25A45,PDCD10,ITGB8,IGSF9,KNDC1,GPC3,TUBGCP6,BAX,RAG1,ACBD5,ADAMTS2,TACC1,DUSP23,PIK3R1,NUB1,CXorf57,UBE2A,AK4,RAB3IP,CNTNAP1,PROM1,PLOD2,SYT7,FAM3C,PPM1H,FBXO44,ITGAV,CD81,ACOT7,SRSF9,PHC1,TNK1,BCAM,KIAA1462,EPAS1,ARFGEF1,DNAJB11,F11R,GALM,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,CTNNB1,ARL1,IL6ST,SLC44A1,ABCA2,NTN4,SCARA3,PLK1,KRT80,THRB,PTPN18,MARK1,CELSR2,CBX6,CR2,CCBL2,CKAP2L,ARFRP1,SESN1,TRUB1,KDM4D,TRIM9,PLEKHG6,PI4K2B,TMEM164,HS6ST1,KCNMB4,HOXA9,KLF11,KPNA2,TC2N,RRAGD,PARP12,RUNX2,USH1C,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,ADCK5,RAB6A,HES2,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,TIMP1,FRAS1,FCHO1,PIM1,NTN1,MPHOSPH9,CKAP4,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,MGAT4B,ZNF320,STRADB,SCRIB,PDK3,BCL2L13,CDK5R1,PRX,RASGRP2,FOXD2,FA2H,OTUD6B,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,CCNB2,USP43,RAD21,TP53,RHPN2,P2RX7,PCBP1,STIL,BCAP31,WDR44,TACC2,LMO4,BCL6,PLK4,NOTCH3,OAS3,LMAN1,SULF2,PPIF,AKT1,KIAA0040,PTGER4,ACO1,PTGS2,TAPBP,ZNF628,PTPRJ,RBL1,STK38,MMP17,MAOA,XRCC3,EFNA5,ARHGAP4,FAM134B,BIN1,ZMAT1,PINK1,DYRK3,CDH22,CPEB4,TAB3,KLHL13,CTSB,GNAL,MCTP2,HAL,CDCA8,ERCC6L,GDF15,HMGN3,AIP,LBR,IL22RA1,NRP2,DNAJB9,SH2D4A,FZD6,M6PR,ZDHHC21,CD109,FOXP2,ALPP,CDK16,UBE2J1,TFAP2A,IL17RA,TRIM21,SGK1,TSPAN13,ALDH7A1,HMGCL,SYK,FAM134C,WBP5,DUSP1,HES1,FBLN5,RHOA,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,DPP9,MAML2,GGH,COL7A1,BBS2,DGKE,USP6,BCL10,DDX23,CNOT2,SCG2,NEIL3,FGF18,E2F1,SH3BGRL2,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,FAM171B,LGR4,HSPG2,VANGL1,TSC22D3,CUL1,PDGFRL,CAMK1D,PICK1,SLC9A7,PAK6,ANKS6,ZNF823,OSBPL3,FOSB,SERINC2,POLL,PIK3CA,SNX16,ARMCX6,SPATA18,ACVR1C,BNIP3L,RAB2B,ANKRD10,SH2D3C,PPP2R4,LRIG1,MAPK13,SERPINI1,SPRY4,F2RL1,FGD1,SEMA6B,RECQL,MRC2,CDKN1C,PRKAA1,AKAP17A,S100A2,TNFRSF19,PDXDC1,TSPAN7,PSIP1,MESDC2,RALGPS2,LYPD3,BHLHE41,RPL39,AIM1,PPP4R1,MSH2,DAPK1,PRKG1,ADCK2,CACNA1D,DLX4,GPR161,TRAK2,SOCS5,PIGC,SPATA20,GCC2,PRODH,KCNJ12,KLK5,ADCK3,DCHS1,WHSC1,NFIB,PDE11A,MMP15,SLCO4A1,PLEKHH2,TJP3,MATN2,PIAS2,MPP2,APPL2,ARAP1,AGBL5,CABIN1,CDK18,KLK7,PER3,IFIH1,MFSD3,SPRED1,KIF3C,TCF25,REPS2,GPR107,CAPN12,ST14,THRA,NDRG1,CERCAM,ATP2C2,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,EPM2A,CD46,APOBEC3B,NOV,CCNA2,TRANK1,RALB,EPHB4,RNASEH2A,PDE4D,DOCK4,FOXJ2,CYB5R2,CLSTN1,UTRN,PKMYT1,ATP1B1,PYGO1,CBL,ITPR3,ASB13,FZD7,ZMPSTE24,DDOST,ACAD10,NGFRAP1,HAGHL,COBL,CBX7,MAMDC2,PRKAR1A,IER5L,CENPI,EPS8,CBLL1,HERC5,PBX3,NES,PLD2,FBXO6,DNAH3,EFNB1,FGF19,COX7A2,HLA-A,WWP2,CKAP5,SCML1,E2F7,TMEM87B,GNB5,RNF128,DRAM1,ERBB3,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,FOS,ARSK,KIF11,CDK5RAP1,CRTC2,TIMP3,FGFR2,RIN3,TBX18,ABCB1,FZD5,ESPL1,CXorf56,DEF6,MELK,RGMA,UBE2Q1,MPP5,PLAC1,TRIM68,ECI1,HTR1D,RAB15,SIPA1L2,CDKL5,ANKFN1,ASH2L,CTTN,STK35,SP5,NLRP4,CENPA,ASXL1,ITCH,ACBD3,USP18,RGAG1,ARHGDIB,GPRC5B,HPSE,MADD,ZNF165,CAB39,SP6,GLA,NR2C2,PCSK5,CD99,LASP1,ARAP3,PPP1R2,PPP1R12A,SERPINE2,ETV5,ASB9,ABCG2,ADAMTSL4,DUSP5,QSOX2,SPP1,NOXA1,PFKL,FAM20C,OCRL,COL6A1,MTMR10,PRKCI,SRP54,BRAT1,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNED1,SNX7,ELK3,KIAA1109,HEATR5A,NUBP1,PDIK1L,STEAP1,MFSD7,RANBP9,RHPN1,INSR,UAP1,TMEM30A,SPAG7,SH3BP4,RAB31,CTSA,SHROOM2,JAK3,TOB1,APOL2,RARG,AFAP1,DRD1,LMO7,CCNE2,LZTFL1,PAX6,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,EXT2,KCTD9,MXD1,SAP130,ZNF687,ZBTB49,DIXDC1,ECE1,ETHE1,UPF3A,EBAG9,CKS2,SOAT1,PTPRU,BTBD19,GLO1,CD40,TMTC2,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,HSF4,STAT6,RCAN2,SPTBN5,LNP1,KDELC2,GLIS3,ENO2,TSPAN15,ARHGEF11,ARHGEF7,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,NTAN1,HMGXB4,ITGA2B,HDAC9,TMEM63A,TOP2A,MZT2A,CARD8,ADRBK1,LLGL2,BMP7,MYCL,TOX2,ZDHHC13,CLIP2,RPGR,MYO5A,PGM1,DCAF6,WNT10B,SYBU,TTC7A,RUNX3,NDRG3,TCEAL8,FOXL1,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,RND3,FIBCD1,RAP2C,ZMIZ1,AHR,RAB3IL1,ABCG1,NGEF,ACACB,KLK10,TRIM24,AASS,TRIM5,DNAJC3,FBXO2,MMADHC,XIAP,CACNA2D2,SMARCAL1,DHX8,FAM102B,NRG2,MORF4L2,CNTROB,SYTL4,BARD1,KIF26A,PHF1,EPDR1,DAPK2,TP73,WEE1,RGS12,KIAA1107,DNAH6,CYP2S1,PPP1R16A,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,TINAGL1,ODF2L,APOBEC3G,NWD1,SMARCA2,TNIP1,SERTAD4,SH3BGRL,RNF11,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,MYOM1,SLC44A3,PGF,TRIM47,GRID2IP,WDR11,LIMK1,MYLK,MAP3K11,SERPINB6,MRPS28,ARF6,PDPR,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,STRN4,MERTK,LMNA,ELF3,WDFY1,FAM189A1,PRICKLE4,NEK2,STT3B,EPHX1,NAGPA,UFD1L,STAT4,MYBL2,SRSF5,TP53INP2,SPTLC2,DCP2,RHOB,STK17A,DHX32,PTPRF,NCOA3,SEMA4D,TIMM8A,HTT,ITPR1,DYSF,AURKA,MDH1,FBXO27,NDE1,DRP2,TRPC3,ZNF502,SERPINB1,RPS6KA3,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,TMSB15A,GALNT12,FAM131C,RGS20,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,KTN1,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,ACSL4,ARL4D,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,SSH3,LGALS8,FZD4,PLEKHO1,SYNE2,CYS1,RAB38,IRS2,SLC9A6,WWTR1,SIPA1L1,INPP4B,PLEKHG1,PDXK,RGS14,GEN1,ARNT,FARP1,TAOK2,ANO9,PKN1,ARHGEF40,ETS1,TSPAN17,SRPX2,NEO1,CAPN2,CXCL16,ANK1,ADD3,SLC27A6,IRAK1,ANKS1B,KCNK5,CALD1,ALG13,MCF2L,FDXR,PLEKHF1,ADAM15,TMBIM6,NKAPP1,MAPK11,WWP1,CRTAP,HCN3,AMOTL2,CTNNAL1,FMN1,BCL9,RAPGEF2,PLEKHA7,MYEOV,SNTB1,ABLIM2,TXK,PITX2,BTG1,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,CENPE,FHL1,HMGA1,NUP37,SHOX2,FOXA1,TRIM2,AGRN,FAM199X,EPHA4,CUL4B,FHDC1,TP53I11,CDIPT,HDAC6,NUP62CL,PDGFB,PIGL,PCNA,CNTRL,SHC3,ELF5,DUSP10,RGS5,TNFRSF18,ANO4,TLN2,PXMP4,MYBL1,TRAM1,NEB,CCDC38,ZNF462,PCGF5,CD55,HN1L,KLK6,ANLN,PRKRA,IDH1,CLCN2,LHFPL2,ZBTB7B,RHEB,VCP,PLEKHB1,OPTN,TBC1D17,MAP2,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,POMT1,MAFF,PRKAA2,BMF,ASAH1,RACGAP1,CNTNAP2,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,IGF1R,GATA2,SPIN4,TMEM8A,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,EPN3,DHDH,MAPKAPK2,COQ10A,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,CTBP1,RNF146,NIPA1,FAM45A,NF2,UPF3B,FOXM1,DGKA,CCDC68,ERBB2,RASGRP3,SLC7A2,CCNL1,C1orf116,CYP26A1,PER2,RAD23A,CDK14,ATP6V0B,SRPX,PLCG2,GYS1,MINPP1,EGLN3,SCN2A,DVL2,GM2A,CPD,SIRT1,TMTC1,MBP,CDC20,MYL12A,DNAJC10,PRRT4,PTK7,ADAMTS14,ZBTB6,RPL22,AIFM3,ZNF701,CMTM4,MAN2B2,GSDMD,GOLIM4,TRAPPC10,MACC1,RUSC2,GABRG2,PSMD10,NKRF,JAG2,PPP2R3A,SIRPA,MAGEE1,ABCD1,BUB1,FAIM,SLC45A3,CAMK2G,IGDCC4,DLGAP1,HMMR,LITAF,TRIM35,CAPNS1,AKAP3,BCAR1,MAPK8IP1,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,ZNF214,ZMYND19,TMC5,CDCA7L,NETO2,PGRMC1,PPP2R3C,UBE2C,TBC1D4,DIS3L,GAA,ACVR1,PPP4R4,KLC2,PPFIBP2,TAP1,GATA3,PLXNA1,CCNB1,SLC20A1,ELMOD2,CHST2,CTGF,ZFP36,RGS3,PRICKLE3,IQCE,IL31RA,ATRNL1,TFG,SMYD5,LAMP2,ORAI2,TMEM68,KIFC2,PBK,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,PIF1,CCNF,SAV1,SLC25A5,TP53I3,SPNS3,ULK2,AHRR,SFXN1,KDSR,FAM177A1,HLF,RBM47,PLK2,PTER,NKD1,FAM110C,DHTKD1,TANC2,UNC5B,TRAF5,RTN3,LZTS1,DLAT,DDX58,CDK17,INPPL1,FRMD4A,HLA-E,CALB2,DGKQ,KIF23,C6orf106,NOTCH2,BMP2K,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,CTSD,TSPAN33,EEF1D,RIMS2,IGSF3,PMPCB,DDB2,MFI2,KIAA1841,TBC1D8B,AMER1,PTPRH,PIP4K2C,KCTD20,KDM3A,FBXO10,RASA1,FRMD4B,FAS,DGKH,PRKAG2,TMEM54,ISM1,NAB2,SLC4A3,TCEAL4,PCDH19,MAP3K5,NRBP1,PKD1L2,IRF1,ELK4,FRMPD3,PLA2G4A,PLEKHG3,ARMCX3,CEP70,TRIP10,SUZ12,RPS6KA1,IRX4,CD274,NUDT12,AIFM2,GNB2,SLC25A35,APLP2,ZNF75D,FAM46A,DOK4,TNPO2,CDKN1B,CNNM4,PHKA2,LGMN,TMBIM1,TBC1D10B,MYO5B,SLC5A11,SEC23A,CAPN6,TEP1,PRKCQ,BCL7B,AKR1E2,ZNF469,CMTM7,PRDM11,NIN,OSBPL2,EPHA10,FYN,JAK1,PPP2R5A,ACYP1,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,HS3ST3B1,ZC3H12B,MLKL,B4GALT3,NR3C2,ATMIN,DENND5B,OTUD5,ARHGEF3,ANKRD13D,SLC16A14,ARL4C,GPR180,CYB561,APOBEC3H,PNPLA5,SIX4,TMCC3,RND1,SNTA1,C16orf59,PTEN,CENPJ,SGK3,ATP8B1,ERCC2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,OSGIN1,SMC4,RASGRF1,CASK,SHMT1,MPP1,FURIN,PARP4,C1GALT1C1,LRRC1,GPLD1,MAMDC4,RCBTB2,AMMECR1,CSTF2,SERPINB5,ETAA1,NCAPG2,ARSB,CPEB2,OCLN,USP16,JARID2,ESYT2,LTBP1,CASP3,ST13,TMEM184B,CAMKK1,KIF2C,DNER,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,ABCD4,NKAIN3,ARHGEF10L,C7orf49,ZCCHC12,TSPAN6,DLG1,CAPG,POF1B,ANKRD12,RAB20,RP2,ARNT2,TECR,SLC39A10,PTPRE,RASGRP1,ATL1,TRIM8,SYNE3,FOPNL,RNF165,ROR1,ADRBK2,STK17B,MDK,CXXC4,ARHGEF19,NEIL1,FASTKD1,UEVLD,TRIM45,CCDC74B,APBA2,RAP1GAP,PPP2R5D,MIIP,GRN,FAM213B,LRRFIP2,ASL,PHLPP1,OTUD1,AIM1L,CA2,LRRN2,KCNN4,EBF4,FXYD5,KNTC1,LRIF1,ALS2CL,PARD3B,OXR1,GYLTL1B,FBXO8,BTN3A2,RNF113A,AMDHD1,EGFR,MUM1L1,GNAS,XKRX,BCAR3,TSC1,ONECUT1,SLC6A6,NFKBIA,PAPD5,ALPK3,RHOBTB2,PITPNA,EGFL7,KIF12,PROM2,FBXW5,ZSWIM5,SPC25,MORC4,MICALL2,ARHGEF16,SS18,FRYL,SMO,RPN2,TWIST1,APIP,F2R,LOXL1,PDIA6,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,BAG4,TAF5,KREMEN2,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,MAP3K6,BFSP1,BHLHB9,PLXND1,CYP2U1,AKNA,REEP4,PPP2R2D,LIFR,CBX4,CCDC24,CDS2,LRP4,TRMT2B,POMGNT1,IL17RB,SNX13,MDM1,MLPH,GALNS,BRD7,TRIM3,CKS1B,MXD3,HSPA13,IQGAP3,ADAM17,RAB3B,NR4A1,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MAP1B,KLHL2,HLA-B,HNRNPH2,DHRS2,UBE2D2,HOXB13,SOX8,ATP6V1C1,GEM,L1CAM |
| 8.301e-08 | -16.30 | regulation of protein metabolic process | biological process | GO:0051246 | 2557 | 471 | 16441 | 2455 |
TXN,ACVR1,PPP4R4,SSH1,IBTK,GRIK2,TRIM5,DNAJC3,RET,XIAP,FBXO2,CUL1,NRG2,GATA3,PSME1,IL18,CCNB1,SEPT4,SNX9,BARD1,CARD10,RIC1,PHF1,GRM5,TP73,CALM2,CDKN2C,PAK6,PSMD1,CTGF,ZFP36,RGS3,IL31RA,PIK3CA,CRY2,PPP1CA,TIPARP,NEK4,VPS11,TNIP1,ACVR1C,PBK,CASP9,SPRTN,AGO4,PRKAR2B,F12,RNF19B,POR,PIAS3,ENPP1,PLCG1,CAMK2N2,ANKRD6,PLK2,LIMK1,TBX1,TRAF3IP1,PPP2R4,NKD1,NOD2,MAP3K11,SERPINB6,EIF4EBP2,SERPINI1,SPRY4,LSM14B,HSPB1,F2RL1,GAB1,KLF2,CDKN1C,GGA1,NUAK1,SOX9,PRKAA1,RAB23,SH3RF2,MECOM,TFAP4,CALR,RAC2,CYR61,PAIP2B,NECAB3,FBXO7,DAPK1,MAP3K9,SORL1,USP38,USP1,MYDGF,NCAM1,MAPK7,MYLIP,PPP6R1,SOCS5,MMD,MFI2,MAPKAPK3,CALM1,PYM1,EPHA1,ILK,CYFIP2,KDM3A,PSMA4,RASA1,FAS,FNTA,PRKAG2,HTT,SEMA4D,PELI2,FAM83D,AURKA,STK39,EFNA1,GDF11,MAP3K5,SERPINB1,RPS6KA3,XDH,IRF1,SPRED1,DLGAP5,INPP5D,RPS6KA1,CAST,IQGAP1,PTTG1,PRKACA,FLT3,APC2,CCND1,CD46,APLP2,ST5,CCNA2,RALB,DACT1,CDKN1B,DAB2IP,PDE4D,OSBPL7,DLG3,RASGEF1A,CDKN2D,FLOT2,CAMSAP3,PSRC1,RIPK2,FZD4,DMTN,CDCA2,PRKCQ,SLC11A2,PXYLP1,PKMYT1,SNX12,FZD7,IRS2,FYN,JAK1,CCNB3,PPP2R5A,NGFRAP1,STK26,WFS1,CORO1C,WWTR1,KIAA1804,SLC27A1,NRG1,RGS14,ARNT,MAPK12,PRKAR1A,FARP1,PCOLCE,TAOK2,TNRC6C,NKX3-1,HSP90B1,TRAF2,SDC4,FLOT1,HERC5,CTSZ,PKN1,GSTP1,TIPRL,FGF19,ICAM1,SNTA1,DIRAS3,PDCD10,RNF128,IRAK1,CTSC,PTEN,KNDC1,GPC3,CST3,BAX,MAPK11,ERBB3,CNOT6L,MAP3K7,RAG1,GFI1,SPRY2,CRTAP,RASGRF1,PDGFC,RAPGEF2,EIF5A2,NUB1,GRIN1,FURIN,YES1,GPLD1,CDK5RAP1,TIMP3,KIAA0141,FGFR2,ACVRL1,PRDX3,RYK,SERPINB5,GRIN2D,ITGAV,GPER1,CENPE,LRRK1,FZD5,CD81,CPEB2,ESPL1,USP16,JARID2,CCNC,SIGIRR,CASP3,ST13,CNOT8,CAMKK1,CUL4B,EPHA4,ARFGEF1,NDRG2,VARS2,NENF,HDAC6,PDGFB,ERP29,SPTB,FANCI,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,PASK,DLG1,DUSP10,TNFRSF18,SLC39A10,RASGRP1,PLK1,SOD1,CD55,ITCH,USP18,C12orf65,EZR,CDK1,VCP,KDM4D,GPRC5B,MADD,IARS2,PRKCDBP,CAB39,PSMC1,PPP2R5D,LMTK3,PPP1R2,SERPINE2,PPP1R12A,DNAJB2,RASA2,UBASH3B,ASB9,PDCL,PSMD7,CALM3,SORBS3,TEC,PHLPP1,FBLN1,DUSP5,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,FNIP1,MDFIC,BRAT1,NPTN,PIM1,WNT3A,CCDC88A,PSMA5,MDFI,USP31,HMG20B,STRADB,PDE5A,EIF2AK1,BCL2L13,RANBP9,EGFR,CDK5R1,FECH,MAPKAPK2,BCAR3,TSC1,INSR,PLPP3,CSF1,NFKBIA,DCUN1D1,YOD1,CTSA,JAK3,TOB1,CTBP1,IFI6,DRD1,PROM2,USP43,CCNE2,AVPI1,NF2,UPF3B,FOXM1,IL15,PSME2,CTDSPL,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PATL2,EMP2,STIL,BCAP31,SYTL2,PER2,IER3,RAD23A,PDGFA,SVBP,KIF14,PPME1,BCL6,TWIST1,ECE1,APIP,EGLN3,F2R,CTDSP2,HSPA2,DVL2,UPF3A,FRS3,CKS2,CHP1,MAP3K3,SIRT1,SOAT1,TIMP2,ERLEC1,BAG4,AKT1,CDC20,ACO1,DUSP4,CD40,CDC25C,MAP3K6,DAG1,C3orf33,SOCS3,DNAJC10,IDE,PTPRJ,PSMD3,STK38,EFNA5,SPTBN5,CNEP1R1,PPP2R2D,CTDSP1,ARFGEF3,PINK1,CPEB4,TAB3,DAP,SH3D19,SERPINB9,LRP4,PSMD10,TGFBR1,GDF15,TRIB2,PPP2R3A,SH2D4A,CD109,CARD8,ADORA1,BMP7,UBE2J1,CKS1B,H2AFY,TRIM21,BRD7,BUB1,HEXIM2,IQGAP3,SYK,CAMK2G,DUSP1,HES1,ADAM17,RHOA,PSMB4,WNT10B,PLAUR,GCLC,RGCC,PRICKLE1,COL7A1,FXR2,MPV17L2,MAPK8IP1,BCL10,USP6,LEMD2,CNOT2,BANK1,CASP7,SWAP70,SERPINA1,SPINT2,FGF18,RAP2C,NMI,TADA2B,ARRB1,PPP2R3C,PKD2,NDFIP1,UBE2C,HIPK3,PKIA |
| 8.388e-08 | -16.29 | negative regulation of cell cycle | biological process | GO:0045786 | 464 | 112 | 16441 | 2455 |
GAS2L1,HECA,CASP3,CAST,PSME2,CTDSPL,PTTG1,TP53,CUL1,GATA3,PSME1,BCL2L1,VASH1,PLA2G16,PRKACA,BARD1,FANCI,IER3,TP73,SUSD2,CCND1,CDKN2C,BTG3,CCNA2,PSMD1,RPS6KA2,CTNNB1,DACT1,PSMC2,DLG1,CDKN1B,DAB2IP,ZBTB49,CDKN2D,CTDSP2,PLK1,TIMP2,CDC20,RAD17,AURKB,CCNF,SESN1,CDK1,RHEB,JADE1,PTGS2,PLK2,PSMD3,CAB39,HDAC1,OVOL1,MAD2L1BP,E2F8,PSMC1,MIIP,CTDSP1,RRAGD,PRKAR1A,MAPK12,PRKAA2,NKX3-1,CDKN1C,PRKAA1,PSMD7,PSMD10,TGFBR1,NOTCH2,ETS1,CALR,TOP2A,TFAP4,BMP2,E2F7,RB1,PTEN,BMP7,FBXO7,MSH2,H2AFY,BRD7,BUB1,KANK2,HEXIM2,KNTC1,PSMA5,DUSP1,ZWINT,PSMB4,WNT10B,HMGN5,NR4A1,RGCC,STRADB,SCRIB,KIF20B,RUNX3,TRIM35,ILK,NUBP1,PSMA4,RHOB,CDK5RAP1,TSC1,PRKAG2,FGFR2,CGREF1,PKD2,GPER1,FHL1,UBE2C,ESPL1,IRF1 |
| 8.428e-08 | -16.29 | cellular localization | biological process | GO:0051641 | 2209 | 414 | 16441 | 2455 |
SUN1,DOC2A,LAMP1,ACACB,GAA,IBTK,GRIK2,SLC25A13,KLC2,TAP1,GATA3,TRAPPC8,TGOLN2,LGI3,BAIAP3,SYTL4,CCNB1,SNX9,RIC1,PICK1,CALM2,NAPG,AP1M2,CTGF,STEAP2,DNM2,SNX16,TINAGL1,PIK3CD,TFG,PACSIN1,CPE,TUBA4A,LAMP2,VPS11,UXT,BNIP3L,KDELR3,KIF13A,AURKB,ICMT,MCFD2,RNF19B,RAB2B,ARF4,DNM1L,AREG,GNPTAB,ATP7B,TRAF3IP1,NOD2,ARF6,F2RL1,NFKBIE,GGA1,SEC61G,SOX9,RAB23,GPSM2,SLC1A3,APBA1,FAM21C,MERTK,LMNA,ATG4A,MESDC2,CALR,DOPEY2,SNX18,ATP5H,RIMS3,RPL39,NECAB3,FBXO7,RANBP1,SORL1,CADPS2,PIKFYVE,SYTL3,NUP85,PPP6R1,TSPAN33,TMED2,RIMS2,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,CALM1,ERO1A,KIF20B,NPC2,SRSF5,RHOB,PLIN5,STX3,AP1AR,SCARB2,PRKAG2,TIMM8A,HTT,WDR19,ZDHHC20,ITPR1,FAM83D,AURKA,NDE1,HOOK1,NRBP1,NUP58,EHD1,KIF3C,MTM1,CCDC109B,ARMCX3,DLGAP5,THRA,PKP2,FTH1,BCL2L1,ZFYVE9,APPBP2,ACAP2,CDH1,TNPO2,IFIT1,ARL4D,DLG3,RAB27B,FLOT2,SNX10,TBC1D10B,ATG4D,MYO5B,SNX8,SEC23A,SEC61B,PSRC1,COG2,FZD4,DMTN,SYNE2,VPS4B,KIF1C,HTATIP2,NUSAP1,ATP1B1,PYGO1,RAB38,ITPR3,ATP10D,NIN,PEX5,STX10,DDOST,AXL,RAB29,PRIMA1,RGS14,SLC25A30,MZT1,TAOK2,HSP90B1,ATP9A,HABP4,ARL4C,FLOT1,BTN3A1,PDIA3,CTSZ,PLD2,SPDL1,IFT27,TSPAN17,SIX4,PDIA4,ANK1,PDCD10,RNF128,CTSC,FAM160A2,PPP1R10,CD9,BAX,KLC3,PLEKHF1,SPRY2,ZWINT,LCA5,CASK,ZC3H11A,TACC1,RAPGEF2,PIK3R1,MRS2,FURIN,VAMP3,RAB3IP,FAM109A,CNTNAP1,RGPD5,LDLRAP1,RPL12,FGFR2,RAB11FIP2,SYT7,NR4A3,ARFGAP3,SSNA1,CENPE,ARSB,CD81,WDR45B,ESPL1,SRSF9,EXPH5,UNC93B1,UGT8,FAF2,AGRN,CPT2,ARFGEF1,NDC80,UBE2Q1,F11R,MPP5,KIF2C,HDAC6,PDGFB,ERP29,SLC8B1,ZFYVE16,RAB15,CTNNB1,LMAN2L,DPYSL2,ARL1,DLG1,KIF22,SUN3,RAB20,RP2,CTTN,TLN2,TRAM1,MYRIP,S100A13,RASGRP1,PLK1,SOD1,KCNIP3,CENPA,SYNE3,EZR,ARFRP1,CDK1,VCP,OPTN,TRIM9,TBC1D17,WIPI1,RAB11FIP1,KPNA2,TC2N,PCSK5,RRAGD,PRKAA2,GRN,PEX6,ETV5,CALM3,CNTNAP2,RAB6A,PGAP1,SSX2IP,CORO1B,RB1,TIMP1,GATA2,KIF13B,EXOC8,PRKCI,SRP54,BRAT1,WNT3A,NTN1,GAD1,MDFI,KDELR1,BTN3A2,STRADB,SCRIB,NUBP1,ZDHHC3,EGFR,NMT2,GNAS,TSC1,PVRL2,TMEM30A,CDCA5,NFKBIA,SH3BP4,RAB31,ZDHHC7,CTSA,LTBP2,ATP1B3,PLD1,SHROOM2,JAK3,TOB1,DRD1,RAD21,SLC25A24,UPF3B,TP53,P2RX7,MICALL2,EMP2,STIL,BCAP31,SDF4,SYTL2,TTC21B,PDGFA,SVBP,TACC2,KIF14,ZDHHC12,PLCG2,REEP1,BCL6,ZDHHC23,SMO,STEAP3,RPN2,LMAN1,F2R,DVL2,UPF3A,CHP1,PPIF,BAG4,AKT1,PTPRU,AP5M1,DAG1,TAPBP,ALDH5A1,PEX2,MAOA,CHMP4B,SPTBN5,SYT13,RPL22,CNEP1R1,ABCA1,COPG1,ANXA3,PINK1,PACSIN2,SORT1,TRAPPC10,CD63,TSPAN15,SH3D19,FRMD6,LRP4,CDCA8,PSMD10,AIP,VPS26A,HMGXB4,ITGA2B,ZDHHC21,M6PR,KIF5B,SNX13,ADORA1,MLPH,LLGL2,CDK16,BMP7,H2AFY,CPLX1,ABCD1,SYK,RPGR,CAMK2G,MYO5A,SUN2,HES1,RAB3B,FBLN5,CRB3,ASPM,PRICKLE1,COL7A1,AKAP3,BBS2,SCRN2,MAP1B,SERPINA1,SCG2,ARRB1,PKD2,MCUR1,SPCS3,GEM,NDFIP1,ABCG1,SNPH |
| 8.888e-08 | -16.24 | ELVIDGE_HYPOXIA_BY_DMOG_UP | MSigDB lists | ELVIDGE_HYPOXIA_BY_DMOG_UP | 126 | 42 | 17758 | 2588 |
ENO2,ZNF395,NDRG1,SOX9,GDF15,S100A2,PHLDA1,ELF3,SRPX,ARTN,OPN3,GYS1,LIMCH1,PIM1,EGLN3,CITED2,S100A6,OLFML2A,QSOX1,PGM1,NR3C1,S100A4,PLAUR,SAT1,BNIP3L,AK4,LOXL2,DPYSL4,KDM3A,FOS,CYB5A,EGFR,SLCO4A1,FYN,P4HA2,ITPR1,CSGALNACT1,MAFF,CSRP2,KLF7,EGLN1,RRAGD |
| 9.111e-08 | -16.21 | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | MSigDB lists | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | 88 | 33 | 17758 | 2588 |
COL9A3,ENO2,DLGAP5,HJURP,CDCA8,KIF2C,GPSM2,CCNB1,CENPN,NRP2,TOP2A,CCNA2,NEK2,CDH3,BUB1,NCAM1,CKS2,HMMR,CENPA,KIF20A,ASPM,PBK,CDC20,NUSAP1,KIF11,CDK1,GLT8D2,CENPE,UBE2C,SHOX2,CCNB2,ESPL1,MELK |
| 9.151e-08 | -16.21 | KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM | MSigDB lists | KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM | 76 | 30 | 17758 | 2588 |
INPPL1,CDS2,INPP5D,CALM1,DGKQ,PIK3R1,PIP4K2C,DGKA,CALM3,ITPR2,CDIPT,ITPR3,DGKE,CDS1,DGKH,CALM2,INPP5E,PLCG1,PTEN,OCRL,PLCG2,ITPR1,INPP4B,PIK3CA,PIK3C2B,PIK3CD,PIKFYVE,ITPKA,PLCB2,DGKG |
| 9.263e-08 | -16.19 | GSE7852_THYMUS_VS_FAT_TREG_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TREG_DN | 190 | 56 | 17758 | 2588 |
CD99,IER5L,SORBS1,RUNX2,NFKBIE,IL15RA,FAM189A2,ST14,DNAJB2,INPP5D,ASAH1,NCKAP1,PHLDA1,SNX9,TNFSF9,BMP2K,UHRF1BP1L,IER3,PLS3,APOBEC3B,FAM46A,DRAM1,GOT1,TSPAN13,TMEM8A,TIPARP,GM2A,ENPP4,FZD4,RGMB,ADCK3,S100A4,MRS2,CRIP2,PIM3,FOXL1,RHOB,KDSR,HLF,FAM177A1,NR1D2,FAM114A1,ABCB1,PCDH19,ARRB1,PKD2,CTNND1,SP6,PLD1,ITGAV,UNC5B,EPB41L4A,FZD5,ARSB,MAFF,CBX7 |
| 9.371e-08 | -16.18 | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | MSigDB lists | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | 176 | 53 | 17758 | 2588 |
CCNE2,SPC25,DLGAP5,MRPS15,SLC25A13,NDC80,RACGAP1,KIF2C,CCNB1,LMNA,ITGA2B,FANCI,SAC3D1,TOP2A,APOBEC3B,CCNA2,RANBP1,PRC1,NEK2,CKS1B,BUB1,RNASEH2A,MINPP1,NUP85,HMMR,PPIF,ZWINT,CENPA,KIF20A,ASPM,PBK,CDC20,NUSAP1,PRKAR2B,GGH,AURKB,KIF11,CDK1,LEPR,PRDX4,SFXN1,AMMECR1,RAB31,AURKA,STK39,KPNA2,MRPS28,UBE2C,CCNB2,ESPL1,E2F8,ACOT7,MELK |
| 1.003e-07 | -16.12 | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN | 181 | 54 | 17758 | 2588 |
DDX58,TXN,IL15,PARP14,SEC61G,UBE2Z,CD274,MORF4L2,HERC6,PGAP1,DUSP5,CMTM6,ICAM1,CAPN2,BTG3,SESN3,ITGB8,GRHL1,FJX1,CD70,SELK,HSPA13,IFIT1,DUSP1,ARAP2,RIPK2,TNIP1,RAPGEF2,USP18,STAT4,LYRM1,SAT1,NUB1,PTGER4,AK4,RAB3IP,DUSP4,OPTN,SOCS3,GALNT3,BTG1,SWAP70,SERPINA1,UAP1,TRIM69,MFSD2A,NETO2,TDRD7,IRF7,CMPK2,IFIH1,SERPINB1,IRF1,FAM134B |
| 1.026e-07 | -16.09 | HALMOS_CEBPA_TARGETS_DN | MSigDB lists | HALMOS_CEBPA_TARGETS_DN | 43 | 21 | 17758 | 2588 |
GAS2L1,HES1,TSC22D3,ARL4C,TFAP2C,ROR1,RHOB,FZD7,ELF3,BCAR3,SCNN1A,CTGF,CYR61,RGS3,CLDN4,DUSP10,IFIT1,ERBB3,MTMR11,F2RL1,TOB1 |
| 1.033e-07 | -16.09 | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | 471 | 111 | 17758 | 2588 |
SUN1,AVPI1,ATP2C2,C5orf30,CCDC68,RHPN2,PRSS22,CD274,OSR2,BCL2L1,GRK6,KCTD9,LYPD5,SIPA1L2,ZFP36,OSBPL3,IL6ST,ANKRD12,DUSP10,RCAN3,PTPRE,TIAM1,ZNF365,DDX59,MYO5B,NLRP4,ATL1,CITED4,COQ10B,SAT1,PTGER4,MGAM,TFAP2C,DUSP4,DOCK5,ZFAND5,RNF19B,STK17B,IRX3,OSBPL2,IRS2,GPRC5B,AREG,SHROOM3,CAB39,SPRY4,ST3GAL1,CBX4,DDX58,ARHGEF3,CDK17,PARP12,PPP1R2,ENO2,PARP14,ATP9A,RUSC2,ELOVL7,SDC4,SOX9,ARL4C,JAG2,B4GALT4,NFAT5,BMP2K,PARM1,AKIRIN1,RASSF8,AIM1L,RB1,ITGB8,CYR61,CALD1,SGK1,USP38,PIM1,SPRY2,FAM69A,SOCS5,AMOTL2,ADAM17,ARAP2,B3GNT2,RGMB,FAM160A1,GCLC,SYBU,EIF5A2,FHL2,PIM3,NPHP3,BCAR1,C3orf58,RHOB,BCL10,STK17A,BCAR3,IL1R1,BTG1,PRKAG2,KBTBD2,MATN2,PGM2L1,ARFGAP3,HIPK3,AHR,RPS6KA3,KLF7,JARID2,IRF1,EHD1 |
| 1.037e-07 | -16.08 | regulation of Rho protein signal transduction | biological process | GO:0035023 | 107 | 38 | 16441 | 2455 |
PLEKHG3,ARHGEF3,FARP1,ARAP3,ADGRG1,ARHGEF11,ARHGEF7,FLOT1,ARHGEF40,ARHGEF16,EPS8L2,ARHGEF10L,PDCD10,ITGA3,ARHGEF37,MCF2L,BCL6,TIAM1,F2R,ALS2CL,FARP2,RASGRF1,ARHGEF28,SPATA13,ARHGEF26,ABR,ARHGAP35,PLEKHG6,ARHGEF19,PLEKHG1,FGD6,ARRB1,F2RL1,ARHGEF9,ABCA1,ARHGEF4,NGEF,FGD1 |
| 1.056e-07 | -16.06 | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | 827 | 175 | 17758 | 2588 |
ACVR1,TRIM2,PNISR,TRIM24,IBTK,SLC25A13,EPHA4,NDC80,ARFGEF1,CUL1,TRAPPC8,PJA2,BARD1,ZFYVE16,TGFBR3,RPS6KA2,CTGF,MITF,ATP13A3,DLG1,TRPC1,ARNT2,WBP4,MYBL1,TIPARP,TIAM1,IL1RAP,NEK4,SMARCA2,CENPA,ASXL1,ACBD3,ITCH,STAU2,CDYL,ROR1,LHFPL2,TRAM2,LRIG1,TDRD7,STARD13,CDK17,FAM169A,PPP1R12A,NUAK1,ITGA6,SOX9,KIF23,NCKAP1,RAB6A,PHLPP1,DUSP5,BMP2K,MECOM,RB1,DOPEY2,IGF1R,CYR61,PRKCI,MSH2,TPST1,DAPK1,MDFIC,LIMCH1,PIKFYVE,MPHOSPH9,ABCC1,SOCS5,KIAA1109,KIF20B,KDM3A,NFIB,EGFR,RASA1,NMT2,BCAR3,IL1R1,NCOA3,NT5C2,SETD3,PHLPP2,ITPR1,RAB31,OSMR,AURKA,SFMBT1,STK39,AFAP1,RPS6KA3,KLF7,DOCK9,ARHGAP11A,SLC25A24,SPC25,DLGAP5,SUZ12,RGS20,STIL,APPBP2,ZFYVE9,IER3,CCND1,ST5,ACAP2,SP100,EFR3A,FRYL,KIF14,CDKN1B,ACSL4,DOCK4,PTPN9,SYNE2,SLC11A2,DUSP4,ALCAM,ARHGAP35,FYN,PPP2R5A,CDK19,WWTR1,SIPA1L1,TLE1,NRG1,EFNA5,WASF3,CDS2,ARHGEF7,GNE,EPS8,PBX3,TIPRL,HOXB2,PPP2R3A,HMGXB4,CKAP5,TOP2A,SNX13,PTEN,FUT8,GTF2F2,ATP8B1,WWP1,RPGR,NCOA2,MSH6,ATP2B1,DUSP1,GCNT1,HMMR,MOB4,TGIF1,ADAM17,ARAP2,CASK,PLSCR1,NR3C1,PLAUR,RAPGEF2,FNDC3A,KIF11,MAP1B,USP6,CNOT2,SWAP70,PLOD2,CCDC6,UBE2D2,RYK,PKD2,CENPE,ZMIZ1,MELK,JARID2,TMEM131 |
| 1.060e-07 | -16.06 | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | MSigDB lists | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | 509 | 118 | 17758 | 2588 |
KIF3C,PSME2,KLC2,TAP1,FBXO2,UBE2Z,UBE2Q1,CUL1,RNF182,RASGRP3,PSME1,KIF2C,CD274,ITPR2,PJA2,PRKACA,KIF26A,SPSB1,SH3KBP1,CALM2,RNF220,AP1M2,PSMD1,CDH1,STIM1,PLCG2,PSMC2,PIK3CA,DNM2,CDKN1B,KIF22,PIK3CD,LGMN,RASGRP1,SEC23A,SEC61B,TCEB2,RIPK2,AKT1,CASP9,CDC20,PRKCQ,CD40,ITPR3,ASB13,CBL,SOCS3,TRIM9,PLCG1,FYN,PPP2R5A,PSMD3,RAP1GAP,PPP2R5D,PSMC1,MRC2,NFKBIE,SEC61G,KLHL13,HLA-F,CTSB,PSMD7,ASB9,KIF23,PSMD10,SELL,PDIA3,CALM3,RACGAP1,FBXO6,PHLPP1,ICAM1,HLA-A,DTX3L,CALR,KIF5B,VASP,UBE2Q2,PTEN,PIK3AP1,CTSC,PAK2,KLC3,UBE2J1,PRKG1,TRIM21,WWP1,HLA-C,MAP3K7,CTSD,ULBP2,SYK,PSMA5,PSMB4,KIF20A,NR4A1,PIK3R1,CALM1,UBE2A,YES1,KIF11,PSMA4,BCL10,RASGRP2,DCTN6,HLA-B,CD8A,PVRL2,NFKBIA,UBE2D2,ERAP1,FBXO44,CTSA,ITGAV,FBXO27,ICOSLG,UBE2C,CD81 |
| 1.090e-07 | -16.03 | BURTON_ADIPOGENESIS_3 | MSigDB lists | BURTON_ADIPOGENESIS_3 | 101 | 36 | 17758 | 2588 |
CCNE2,MTM1,DLGAP5,NQO1,CDCA8,RACGAP1,IL13RA1,KIF2C,CCNB1,TOP2A,PCNA,LMO4,PRC1,CKS1B,KIF22,BUB1,USP1,CKS2,PLK1,KIF20A,FIGNL1,CDC20,NUSAP1,CCNF,KIF11,CDK1,PRIM1,DCK,CSTF2,AURKA,OSMR,KPNA2,KLF5,CCNB2,ABCA1,CSRP2 |
| 1.127e-07 | -16.00 | GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 191 | 56 | 17758 | 2588 |
FARP1,IBTK,DHPS,CENPI,NDRG1,CUL4B,SOD2,MIER3,KIF23,GMCL1,FAM91A1,GPSM2,VASH1,BCAP31,BMP2K,ZDHHC21,SNX18,LMAN2L,PRC1,SNX16,SLAIN2,KIF22,MAP3K7,SGCB,SLC12A2,SNX10,TIAM1,MYO5A,TRAK2,CKS2,CENPA,PLSCR1,ASXL1,RAPGEF2,CDC20,ACO1,CCDC34,FBXO9,C2orf69,AURKB,ANLN,CDC25C,FRMD4B,NIN,TMEM50B,IDE,CDCA4,SLC25A4,OTUD6B,SLC9A6,ITPR1,CSTF2,CHMP4B,RTN3,RAD21,DLAT |
| 1.198e-07 | -15.94 | epithelium development | biological process | GO:0060429 | 979 | 205 | 16441 | 2455 |
EXPH5,EMX1,CASP3,ACVR1,LGR4,RET,MCOLN3,EPHA4,CCNO,GATA3,MPP5,F11R,PLXNA1,PDGFB,SDC1,TMC1,PLS3,EPCAM,CYP1A1,PCNA,CTNNB1,CTGF,GRHL1,NPNT,ALDH1A3,MITF,ELF5,DLG1,TACSTD2,PPP1CA,THRB,SOD1,EZR,TFAP2C,LDB2,SAV1,CDK1,ARHGEF26,LCP1,EDNRA,IRX3,AGPAT2,AREG,TBX1,PTER,TRAF3IP1,TDRD7,HDAC1,F2RL1,E2F8,GAB1,HOXC13,KLF2,USH1C,LGALS3,SERPINE2,TMTC3,SOX9,RAB23,GPSM2,NCKAP1,TNFRSF19,ELF3,MECOM,BMP2,VASP,CA2,IGF1R,CYR61,FAM20C,MEGF8,FRAS1,FLRT3,NTN1,WNT3A,SLC12A2,ALDH3A2,EPB41L5,KLK5,SALL4,DCHS1,SHARPIN,SCRIB,KIF20B,NPHP3,ILK,NFIB,EGFR,GNAS,ONECUT1,NCOA3,TSC1,INSR,FA2H,HTT,CSF1,KLK7,GDF11,SEMA3A,RARG,ADAMTS16,PAX6,NF2,GRHL2,LFNG,ST14,THRA,IQGAP1,TP53,COL18A1,PRKACA,DDR1,STIL,PDGFA,CCND1,SETDB2,LMO4,SMO,CDH3,TWIST1,PDE4D,DLG3,FLOT2,ETV4,DVL2,AKT1,DAG1,FZD7,SOCS3,ARHGAP35,BFSP1,SHROOM3,PTK7,STAT6,STAT1,OVOL1,NRG1,KLF5,PLXND1,LTA4H,COBL,CTHRC1,NKX3-1,CTSB,FRMD6,CCM2,LRP4,SDC4,CTSZ,JAG2,CRABP2,HOXB2,FZD6,PPP2R3A,ICAM1,SIX4,GBX2,ZDHHC21,CD109,CTNNBIP1,E2F7,PDCD10,GPC3,BMP7,CST3,TFAP2A,BAX,ACTA2,ERCC2,TAGLN2,MAP3K7,CITED2,GFI1,SPRY2,MYO5A,TGIF1,HES1,ADAM17,RHOA,FMN1,RAPGEF2,PPARA,PRICKLE1,COL7A1,FNDC3A,BCL10,ARHGAP24,PITX2,PROM1,FAT4,ACVRL1,FGFR2,CTSV,DBI,SPINT2,RAP2C,TBX18,SERPINB5,PKD2,HOXB13,PLOD3,FZD5,OSR1,SOX8,FOXA1 |
| 1.203e-07 | -15.93 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | 93 | 34 | 17758 | 2588 |
GAS2L1,INPP5D,GTF3A,CCND1,ADRBK1,IL6ST,DRAM1,TFAP2A,SGK1,TNFRSF12A,PPP6R1,CKAP4,IGSF3,AMOTL2,RNF11,NFE2L1,VAMP3,LOXL2,ASB13,GNA11,DAG1,NFIB,LCP1,ULK2,GABARAPL1,BCAR3,SWAP70,PLK2,FAM114A1,WWTR1,BMP1,ITGAV,ARHGAP4,DEF6 |
| 1.299e-07 | -15.86 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP | 187 | 55 | 17758 | 2588 |
BIN1,KLF2,SIGIRR,SLC35D2,HECA,CCDC109B,TSC22D3,EPHA4,TMX4,ARL4C,HERC5,NDRG2,CCNL1,NUCB2,FAM46C,TOP2A,MARCH8,ADD3,ENTPD4,LYPD3,MGAT4A,KLF3,PIK3CA,SORL1,CRY2,PDE4D,PIKFYVE,CITED2,MYBL1,TRIM62,SUN2,S100A4,SH3BGRL,PIK3R1,BNIP3L,PRKCQ,ARHGDIB,FOS,NDRG3,MYL12A,RASGRP2,IRS2,CNOT2,BTG1,PLCG1,RAB11FIP2,PIAS2,CSGALNACT1,PPP1CB,NR4A2,FHL1,MAP3K5,NR3C2,TOB1,PHC1 |
| 1.304e-07 | -15.85 | extracellular matrix organization | biological process | GO:0030198 | 369 | 93 | 16441 | 2455 |
LTBP1,CASP3,HSPG2,AGRN,P3H2,COL18A1,F11R,DDR1,PDGFB,SDC1,LTBP3,PDGFA,APLP2,CDH1,CTGF,NPNT,P4HB,CAPG,NTN4,NFKB2,LOXL1,CYP1B1,SULF2,OLFML2A,TIMP2,COL6A2,LOXL2,DAG1,COL12A1,LCP1,BMP1,ADAMTS14,POMT1,CAPN1,COL9A3,LGALS3,CTSB,ITGA6,SOX9,LRP4,SDC4,FLOT1,COL4A5,TGFBR1,FBLN1,ADAMTSL4,ITGA2B,ICAM1,ELF3,BMP2,SPP1,ITGA3,ITGB8,TIMP1,CYR61,BMP7,CST3,COL6A1,EXOC8,ADAM15,ERCC2,CTSD,WNT3A,NCAM1,CRTAP,ADAMTS2,CASK,FBLN5,ADAM17,ERO1A,FURIN,VWA1,COL7A1,CAPNS1,ILK,NPHP3,CRISPLD2,PRDX4,MMP15,CTSL,PLOD2,COL13A1,ITGA7,CTSV,SPINT2,CSGALNACT1,SERPINB5,KLK7,LTBP2,ITGAV,PLOD3,COL16A1,TLL2 |
| 1.318e-07 | -15.84 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_UP | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_UP | 173 | 52 | 17758 | 2588 |
CCNC,EMX1,SEC61G,MORC4,CYB561,HMGN3,ISYNA1,MORF4L2,MGST2,GSTP1,FAM46C,LMNA,IL17RB,SH3D21,TM9SF2,METTL7A,MEGF8,KNDC1,OSBPL3,CST3,SGK3,PRKCI,RPN2,KNTC1,AK3,PACSIN1,LMAN1,ITM2C,CCDC88A,WBP5,FBXL16,NRBF2,DENND1B,SYNE2,PARP4,ZKSCAN2,GGH,EAF2,PRRC1,TP53I3,RANBP9,RAB2B,RHPN1,PRDX4,CXXC4,MAP2,CGREF1,ARFGAP3,SPCS3,ALG2,APBA2,GLCCI1 |
| 1.323e-07 | -15.84 | single-organism metabolic process | biological process | GO:0044710 | 4618 | 797 | 16441 | 2455 |
ACACB,MRPS15,AASS,AK7,SLC25A13,PNPLA2,HEXB,RET,CACNA2D2,FBXO2,MMADHC,SMARCAL1,CCNO,NRG2,TRAPPC8,IL18,MORF4L2,CA8,BARD1,TP73,CALM2,PHYHIP,PSMD1,MUC4,UBE2T,CYP2S1,ALDH1A3,SLC46A1,RDH14,FUT1,DNM2,CRY2,PPP1CA,PIK3CD,ACOX2,TIPARP,MGAT5,APOBEC3G,NEK4,SPRTN,CDA,MTRF1L,PRKAR2B,LOXL2,F12,ICMT,MYOM1,PNKD,CYP4F3,ARF4,GINS4,COL12A1,SLC44A3,ENPP1,PLCG1,MID1IP1,MYLK,NOD2,MAP3K11,HDAC1,MRPS28,ITPKA,PDPR,GAB1,ALDH6A1,CYP2J2,SOX9,COX6C,ATG4A,GNS,ZCCHC17,ATP5H,RIMS3,FBXO7,FAM13B,PCYOX1,MAP3K9,USP1,ALPK1,STT3B,NCAM1,MAPK7,MOXD1,NDUFA12,NUP85,PHKG2,PPP6R1,MCCC2,EPHX1,NAGPA,REC8,UFD1L,PQLC3,MAPKAPK3,ERO1A,FHL2,CALCRL,ELK1,NPHP3,PCTP,SPTLC2,GOLT1A,PSMA4,CYB5A,NAAA,NCOA3,MTFMT,HTT,SETD3,TEX30,ITPR1,DGAT2,AURKA,MDH1,STK39,B4GAT1,ALG2,NUP58,RPS6KA3,XDH,EGLN1,MTM1,NQO1,PAPSS2,GALNT12,INPP5D,ACTR8,PTTG1,ETNK1,WDTC1,MAPK4,MGST2,PRKACA,MOCS1,CDS1,MUC16,SP100,XYLT2,ACSL4,DLG3,RASGEF1A,CDKN2D,ENPP4,SEC61B,COL6A2,RIPK2,AGPS,PFKFB2,SAT1,HTATIP2,PXYLP1,XRCC6BP1,COX20,GABARAPL1,IRS2,ALDH3B1,WFS1,INPP4B,PNPLA6,TRABD2A,PDXK,GEN1,MAPK12,GALK1,TAOK2,HSP90B1,GCAT,MAN1A2,CCM2,SDC4,OSGIN2,PDIA3,CTSZ,PKN1,PLPPR4,GSTP1,SGPL1,DTX3L,FUT2,ITGB8,IRAK1,SLC27A6,CTSC,ARSG,GPC3,ALG13,MGAT4A,FDXR,BAX,ECI2,ADAM15,MAPK11,AK3,RAG1,TMX1,CRTAP,PARP9,ACBD5,OPLAH,ADAMTS2,PLSCR1,RAPGEF2,PIK3R1,EIF5A2,ELOVL3,GRIN1,UBE2A,AK4,BLVRA,GALNT3,LDLRAP1,PLOD2,ATXN7L3,ACVRL1,SLC35B3,DBI,PLA2G15,NR4A3,ITGAV,HMGA1,CMPK2,NUP37,CD81,WDR45B,ACOT7,CYBRD1,PHC1,AGRN,CUL4B,SUDS3,MCCC1,LMCD1,PHOSPHO1,TEX2,ITPR2,MGAT5B,GALM,CDIPT,HDAC6,PDGFB,SDC1,PIGL,SPTB,FANCI,INPP5E,PCNA,ENTPD4,NUP210,RPS6KA2,SHC3,P4HB,IL6ST,ARL1,PSMC2,PAPSS1,DDHD2,SLC44A1,ABCA2,DUSP10,PLK1,CD55,NFE2L1,C12orf65,CR2,CCBL2,EZR,KLK6,PRKRA,IDH1,CDK1,VCP,KDM4D,PLCH1,HS6ST1,TRAM2,PI4K2B,MSL1,AGPAT2,WIPI1,P4HA2,DOLPP1,KPNA2,PIK3C2B,POMT1,HS6ST3,PRKAA2,DNAJB2,RASA2,PSMD7,ASAH1,B4GALT4,FBLN1,DHRS3,RSAD1,PGAP1,B4GALNT1,BMP2,PAK2,MDFIC,AHCY,FAR2,PLCB2,ALDH3A2,PSMA5,ABCC1,CYP26B1,CHSY3,MRPS33,MGAT4B,STRADB,EIF2AK1,PDK3,MAPKAPK2,DHDH,FA2H,COL13A1,PRPS2,P4HA3,FAM213A,PLD1,CTBP1,USP43,RAD21,UGP2,FOXM1,P3H2,XYLT1,TMX4,TP53,P2RX7,ERBB2,RASGRP3,SLC7A2,LPIN3,CYP26A1,PER2,RAD23A,PDGFA,KMT5C,PPME1,PLCG2,SRR,GYS1,VAT1,MINPP1,LMAN1,EGLN3,FAR1,GM2A,SULF2,CTH,SIRT1,ERLEC1,AKT1,FIGNL1,PTGER4,ACO1,PTGS2,DUOX1,DNAJC10,PAFAH1B3,ABHD12,PSMD3,ADAMTS14,MAOA,XRCC3,C1orf43,AIFM3,LTA4H,ST3GAL1,CNEP1R1,POMGNT2,NDST3,MAN2B2,COL9A3,CMAS,PINK1,TRAPPC10,TAB3,CTSB,SCD5,HAL,BLVRB,GNE,SWI5,PSMD10,CRABP2,DSE,LBR,DNAJB9,ZDHHC21,UBE2J1,ALDH7A1,HMGCL,ABCD1,SYK,CAMK2G,GCNT1,FAH,HMMR,MLEC,PSMB4,GUSB,AMFR,PLAUR,PPARA,COL7A1,GGH,RNPEP,MAPK8IP1,DGKE,PRDX4,FUCA1,DDAH1,SERPINA1,SCG2,NAT1,NEIL3,FGF18,ACADM,PTGES,CFAP61,GAA,SLC35D2,TXN,ACVR1,HSPG2,TMEM86B,CUL1,PSME1,NANS,CCNB1,OAT,PLA2G16,CHST2,ASPHD2,PAK6,TYMP,HELZ2,CYP1A1,CTGF,IL31RA,POLL,STEAP2,KCNS3,SERINC2,AOX1,PIK3CA,TFG,SPATA18,ACVR1C,CDYL,MGAM,SLC35C1,AGO4,PIF1,SLC17A5,GALNT7,AURKB,MCFD2,SLC25A5,TP53I3,POR,PRIM1,SGPP1,KDSR,SLC25A4,AREG,GDE1,GNPTAB,SH2D3C,PRDM5,BMP1,DHTKD1,MAPK13,DLAT,RECQL,MRPL44,MRC2,INPPL1,DHPS,TMEM55B,ADO,PRKAA1,SLC25A27,NDUFA4,ISYNA1,SLC1A3,TNFRSF19,PDXDC1,CALR,BDH1,CTPS1,MSH2,PRKG1,SORL1,CACNA1D,PIKFYVE,CTSD,TMED2,TRAK2,PIGC,GFPT1,FADS2,PRODH,B3GNT7,QSOX1,PMPCB,DDB2,ADCK3,LPGAT1,CALM1,PIP4K2C,PYGL,WHSC1,NPC2,PKM,KDM3A,JADE2,GLT8D2,RASA1,PDE11A,MMP15,NT5C2,PRKAG2,FAAH,DCK,MPP2,SAMD8,MAP3K5,PLA2G4A,ELK4,SPRED1,SLC2A4,RPS6KA1,IQGAP1,SUZ12,FTH1,AIFM2,NUDT12,CYP39A1,GNB2,ART5,EPM2A,CD46,APLP2,DOK4,DAB2IP,RNASEH2A,PDE4D,PHKA2,LGMN,SULT2B1,NAGA,GPX4,ATG4D,SEC23A,CYB5R2,PANK1,TEP1,PRKCQ,SLC11A2,ATP1B1,RAD17,B3GALNT2,ITPR3,AKR1E2,FYN,DDOST,JAK1,ACAD10,STK26,KIAA1804,TRIOBP,PPP1CB,SLC27A1,NRG1,HS3ST3B1,B4GALT3,SLC27A3,PRKAR1A,MRPS9,CYB561,PLD2,APOBEC3H,FBXO6,SPR,FGF19,PNPLA5,OXCT1,MGAT1,PTEN,FUT8,CD9,ATP8B1,SLC44A2,ERCC2,ERBB3,MAP3K7,TTPA,OSGIN1,MSH6,NCOA2,RASGRF1,PCCB,SHMT1,B3GNT2,CASK,ALDH2,PAPD7,MPP1,FURIN,PARP4,C1GALT1C1,FOS,ARSK,CPTP,GPLD1,CRTC2,CTNS,ACADSB,FGFR2,PRDX3,ABCB1,PGM2L1,GRIN2D,ARSB,SLC25A38,OCLN,USP16,NMRK1,FAF2,UGT8,CRYM,CPT2,EPHX4,VARS2,TAF6L,CACNB4,MAP1LC3B,ECI1,ABCD4,CHPF,GRHL1,IMPAD1,DLG1,AKR1B1,TRPC1,KIF22,ASH2L,TECR,RASGRP1,CYP1B1,CERS2,TDP1,SOD1,ASXL1,ACBD3,MRPS18A,MRPS36,ADRBK2,TCN2,MAN2A2,NEIL1,FASTKD1,HPSE,DHRS13,UEVLD,IARS2,CAB39,ADIPOR1,GLA,CHPT1,PSMC1,PPP2R5D,NR2C2,FAM213B,PPP1R2,PYROXD2,ELOVL7,ABCG2,ASL,CALM3,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,CA2,CES2,PFKL,OCRL,COL6A1,BRAT1,ACAD8,NCEH1,GAD1,MDFI,OXR1,GYLTL1B,PDE5A,NUBP1,STEAP1,AMDHD1,EGFR,GLCE,FECH,GNAS,NUDT16,ONECUT1,SLC6A6,INSR,UAP1,PLPP3,CDCA5,RAB31,CTSA,PITPNA,YOD1,JAK3,APOL2,COL16A1,PSME2,HDAC11,PDIA5,SOD2,GMPR,COL18A1,EXT2,SAP130,SETDB2,CYP4F11,FABP6,STEAP3,RPN2,GOT1,APIP,ETHE1,LOXL1,FRS3,CHP1,MAP3K3,SOAT1,TAF5,RFK,MRPS35,GLO1,DUSP4,FANCE,PDHX,MAP3K6,JADE1,HSF4,ALDH5A1,PEX2,SPTBN5,CYP2U1,ABCA1,KDELC2,GCLM,CDS2,ENO2,SHPRH,CIT,JKAMP,TGFBR1,COL4A5,POMGNT1,HDAC9,TOP2A,ADORA1,ADRBK1,A4GALT,GALNS,IQGAP3,SLC35A1,MYO5A,B3GALT6,PGM1,ADAM17,WNT10B,GCLC,RGCC,OGDHL,NADK2,POLD3,LEPR,CTSL,MARC1,SWAP70,DHRS2,PRCP,CSGALNACT1,TADA2B,ARRB1,GLB1,PLOD3,ABCG1 |
| 1.328e-07 | -15.83 | ATP binding | molecular function | GO:0005524 | 1456 | 286 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,PIK3CD,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,KIF13A,PIF1,AURKB,ULK2,ENPP1,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,KIF23,MERTK,BMP2K,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,TRANK1,FICD,EPHB4,ACSL4,MYO5B,RIPK2,PFKFB2,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,ATP10D,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,PDXK,MLKL,MAPK12,GALK1,HSP90B1,TAOK2,ATP9A,PKN1,DNAH3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,OPLAH,PCCB,CASK,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RPS6KA2,CDKL5,PAPSS1,PSMC2,PASK,ABCA2,KIF22,MYH14,DDX59,STK35,PLK1,NLRP4,MARK1,ROR1,ADRBK2,STK17B,CDK1,VCP,PI4K2B,IARS2,PIK3C2B,PSMC1,PRKAA2,LMTK3,RUNX2,PEX6,ABCG2,TEC,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,PIM1,ABCC1,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,MAPKAPK2,INSR,PRPS2,NLRC5,ALPK3,KIF12,JAK3,TP53,DGKA,ABCG4,P2RX7,ERBB2,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,DYRK3,PINK1,TOR4A,CIT,SHPRH,GNE,ERCC6L,TGFBR1,TOP2A,KIF5B,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,ABCD1,BUB1,HSPA13,SYK,MYO5A,ATP2B1,CAMK2G,P2RX4,GCLC,NADK2,RUNX3,DGKE,DDX23,SWAP70,UBE2D2,UBE2C,HIPK3,ABCG1 |
| 1.336e-07 | -15.83 | WANG_LMO4_TARGETS_UP | MSigDB lists | WANG_LMO4_TARGETS_UP | 336 | 85 | 17758 | 2588 |
LTBP1,BCAM,ST13,NDRG1,RET,C5orf30,F11R,EMP2,BCAP31,SUSD2,WEE1,ANKS6,CTNNB1,TM9SF2,ATP13A3,DLG1,BCL6,APIP,TIAM1,TIPARP,S100A13,ANKRD9,MAP3K3,SOAT1,FBXL16,AKT1,TMEM43,LGALS8,SERTAD4,DSTN,VPS4B,TFAP2C,CDCA2,ATP1B1,SFXN1,CAPN1,NR2C2,PRKAR1A,CTDSP1,GRN,ANKRD13D,HSP90B1,CPEB4,DCAF7,MAN1A2,CYB561,PM20D2,DNAH3,WWP2,CALR,RALGPS2,SNX18,FAM20C,NECAB3,SLC16A6,BMP7,SGK3,PCYOX1,IGFBP2,AHCY,AK3,SLC35A1,SYPL1,RGMB,LPGAT1,MBNL3,LITAF,HMG20B,FBXO8,WHSC1,NDRG3,RHOB,CNOT2,IL1R1,TMEM50B,ETS2,KIAA0141,SYT7,DHRS2,DBI,PGRMC1,PITPNA,ZMIZ1,TMEM120A,PROM2 |
| 1.355e-07 | -15.81 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | 106 | 37 | 17758 | 2588 |
EPAS1,ETV5,IL18,PRSS22,CA2,TIMP1,SGK3,OPN3,CADPS2,NTN4,HSPA13,MYBL1,ULBP2,ZNF365,CPE,SLC45A3,S100A6,CYP1B1,TUBA4A,DOCK4,TIMP2,TACC1,SAT1,FHL2,MYEOV,IGSF8,MUM1L1,COL12A1,DHRS2,CDCA7L,FAM110C,MAOA,SYT13,PLD1,TTC9,ISOC1,FAM134B |
| 1.368e-07 | -15.80 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP | 192 | 56 | 17758 | 2588 |
DLGAP5,HJURP,PTTG1,NDC80,CDCA8,GATA3,RACGAP1,KIF2C,CCNB1,STIL,FANCI,CKAP5,ATG4A,CAPN2,PCNA,CCNA2,FUT8,PRC1,PLK4,KIF22,KNTC1,MPHOSPH9,MCCC2,CKS2,HMMR,PLK1,TDP1,SHMT1,ZWINT,CENPA,KIF20A,ASPM,SEPT6,STAU2,CDC20,EZR,NUSAP1,GGH,DUSP4,KIF11,CDC25C,CDK1,PRIM1,FECH,NEIL3,AURKA,STK39,PIEZO1,CENPE,UBE2C,CCNB2,ESPL1,PKIA,MELK,DEF6,GOLGB1 |
| 1.409e-07 | -15.78 | regulation of cell adhesion | biological process | GO:0030155 | 613 | 139 | 16441 | 2455 |
CASP3,RET,GATA3,IL18,EPCAM,CTNNB1,NPNT,IL6ST,PIK3CA,DLG1,DNM2,TNFRSF18,TACSTD2,RASGRP1,CYP1B1,SOD1,CD55,CELSR2,ITCH,ARHGDIB,NOD2,SERPINI1,PIEZO1,RAP1GAP,SERPINE2,PPP1R12A,LGALS3,DHPS,NUAK1,ITGA6,HLA-E,UBASH3B,SOX9,FAM21C,FBLN1,BMP2,CALR,SPP1,RAC2,ITGA3,CYR61,PAK2,TBCD,PRKG1,FXYD5,C10orf54,WNT3A,MAPK7,SOCS5,EPB41L5,MFI2,PDE5A,EPHA1,ILK,STX3,RASA1,SOX13,TSC1,ONECUT1,AP1AR,SEMA4D,PLPP3,CSF1,EFNA1,ARPC2,JAK3,COL16A1,IRF1,LMO7,NF2,IL15,ERBB2,CD274,EGR3,EMP2,TNFSF9,CD46,CDH1,KIF14,BCL6,EPB41L4B,FLOT2,BAG4,AKT1,RIPK2,LGALS8,FZD4,DMTN,UTRN,PRKCQ,FZD7,FYN,PTPRJ,CORO1C,TRIOBP,PPP1CB,NRG1,EFNA5,PRKAR1A,ADGRG1,TRAF2,ARHGEF7,SDC4,FLOT1,CBLL1,JAG2,EFNB1,HLA-A,ICAM1,RND1,PTEN,BMP7,ADAM15,IGFBP2,ERBB3,RAG1,MAP3K7,CITED2,SYK,HES1,CASK,RHOA,FMN1,PIK3R1,RGCC,PPARA,YES1,CD83,BCL10,SWAP70,ACVRL1,TBX18,SPINT2,NR4A3,ITGAV,ICOSLG,NDFIP1,L1CAM,FOXA1 |
| 1.489e-07 | -15.72 | MODULE_19 | MSigDB lists | MODULE_19 | 306 | 79 | 17758 | 2588 |
MYL9,PAPSS2,HSPG2,EPAS1,NQO1,IQGAP1,TMX4,GMPR,ITPR2,SEPT4,CCND1,CDKN2C,NOV,PHYHIP,TGFBR3,ST5,SRPX,PLCG2,FOSB,PSMC2,AOX1,BCL6,DNM2,RGS5,IFIT1,CPE,SGCE,CD55,COL6A2,CBX6,ACO1,MCFD2,HLF,AGPAT2,WWTR1,TLE1,MAOA,BIN1,PCOLCE,CDKN1C,IGFBP6,ALDH6A1,CALB2,AKAP17A,TRIB2,SEPP1,MERTK,TSPAN7,NECAB3,GPC3,COL6A1,SGK1,ALDH7A1,CITED2,NCAM1,DLX4,ALDH3A2,RIMS2,EPHX1,FADS2,NR4A1,EMP3,TCF7,FOS,EGFR,CDK5R1,CYB5A,RHOB,IL1R1,FUCA1,TIMP3,SCG2,PVRL2,ITGA7,ITPR1,TCEAL4,SLC4A3,ABCB1,RAB31 |
| 1.491e-07 | -15.72 | extracellular structure organization | biological process | GO:0043062 | 370 | 93 | 16441 | 2455 |
CASP3,LTBP1,HSPG2,AGRN,P3H2,COL18A1,F11R,DDR1,PDGFB,SDC1,LTBP3,PDGFA,APLP2,CDH1,CTGF,NPNT,P4HB,CAPG,NTN4,NFKB2,LOXL1,CYP1B1,SULF2,OLFML2A,TIMP2,COL6A2,LOXL2,DAG1,COL12A1,LCP1,BMP1,ADAMTS14,POMT1,CAPN1,COL9A3,LGALS3,CTSB,ITGA6,SOX9,LRP4,SDC4,FLOT1,COL4A5,TGFBR1,FBLN1,ADAMTSL4,ITGA2B,ICAM1,ELF3,BMP2,SPP1,ITGA3,ITGB8,TIMP1,CYR61,BMP7,CST3,COL6A1,EXOC8,ADAM15,ERCC2,CTSD,WNT3A,NCAM1,CRTAP,ADAMTS2,CASK,FBLN5,ADAM17,ERO1A,FURIN,VWA1,COL7A1,CAPNS1,ILK,NPHP3,CRISPLD2,PRDX4,MMP15,CTSL,PLOD2,COL13A1,ITGA7,CTSV,SPINT2,CSGALNACT1,SERPINB5,KLK7,LTBP2,ITGAV,PLOD3,COL16A1,TLL2 |
| 1.496e-07 | -15.72 | GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN | MSigDB lists | GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN | 183 | 54 | 17758 | 2588 |
DDX58,DYRK3,PARP12,AGRN,FAM160B1,IL15,HAPLN3,ELOVL7,SERPINB9,SDC4,SOD2,OSGIN2,GMPR,IRX4,PDGFRL,CD274,HERC6,TNFSF9,DUSP5,ICAM1,DTX3L,PDGFA,FAM46A,TRIM21,OAS3,ATP2B1,LAMP3,KIAA0040,LAP3,STAT4,NUB1,C3orf52,SAV1,BCL2L13,CD40,RNF19B,FAS,STK17A,SOCS3,PTGS2,PVRL2,NFKBIA,NMI,SLC2A6,NLRC5,TDRD7,HS3ST3B1,KIF12,CMPK2,RBM43,SLC31A2,IFIH1,MAD2L1BP,IRF1 |
| 1.579e-07 | -15.66 | GSE27786_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NKCELL_DN | 188 | 55 | 17758 | 2588 |
CASP3,LRP4,BLVRB,HEXB,C6orf106,RASGRP3,DHRS3,VPS26A,ATP6V0B,E2F7,SLC25A45,MDM1,CA2,TM9SF2,OSBPL3,IL31RA,PAPSS1,APIP,ALPK1,ARL4D,SCARA3,CNPY3,FAR1,SNX10,SPRY2,SLC45A3,NAGPA,HES1,KIAA1841,GUSB,MPP1,ITCH,CAPNS1,NUSAP1,ANLN,PCTP,ARSK,NFIX,TNS4,MAPKAPK2,SLC6A6,PPP2R5A,RBM47,NIPSNAP3A,DBI,C1orf21,ADIPOR1,NFKBIZ,MLKL,LRRK1,GEM,MAP3K5,ARSB,JARID2,NXT2 |
| 1.579e-07 | -15.66 | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_UP | 188 | 55 | 17758 | 2588 |
PLA2G4A,ST13,ARMCX3,FRMD4A,REPS2,GNPDA1,HEBP1,SLC25A13,RAB23,PBX3,IL13RA1,TEX2,BCL2L1,MGST2,NTAN1,PPP2R3A,DPYSL2,PAQR5,PPME1,GALNS,ADAM15,TECR,ETHE1,CLIP2,CKS2,CERS2,SOCS5,PPIF,AMOTL2,MRPS33,SAT1,ACO1,PLS1,PCTP,RNPEP,ALCAM,KIF11,VCP,CD83,FUCA1,SLC6A6,CTNS,PRDX3,H1F0,CCDC6,CSF1,DBI,CLIP4,CLMN,ADIPOR1,PDXK,FZD5,HSPB1,NRGN,RTN3 |
| 1.588e-07 | -15.66 | guanyl-nucleotide exchange factor activity | molecular function | GO:0005085 | 194 | 57 | 16491 | 2452 |
PLEKHG3,ARHGEF3,FARP1,ARHGEF11,ARHGEF7,ARFGEF1,RASGRP3,SBF1,DOCK11,ARHGEF40,DENND2D,RIC1,ARHGEF16,EPS8L2,ARHGEF10L,ST5,RALGPS2,ARHGEF37,RINL,MCF2L,KNDC1,FNIP1,RASGEF1A,TIAM1,RPGR,ALS2CL,RASGRP1,FARP2,DOCK4,RASGRF1,ARHGEF28,DENND1B,RAPGEF2,SPATA13,FBXO8,RAB3IP,DOCK5,ABR,ARHGEF26,RASGRP2,BCAR3,PLEKHG6,ARHGEF19,RCBTB2,SH2D3C,MADD,RIN3,PLEKHG1,FGD6,ARHGEF9,RAB3IL1,NGEF,DOCK9,ARFGEF3,ARHGEF4,FGD1,DENND5B |
| 1.588e-07 | -15.66 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | 673 | 147 | 17758 | 2588 |
CUL4B,MCOLN3,NDC80,MORF4L2,CCNB1,ATP13A3,DLG1,PIK3CA,HYLS1,MYBL1,IL1RAP,FGFR1OP2,KRT80,CENPA,ITCH,CDYL,ROR1,AURKB,ANLN,STK17B,CDK1,TRUB1,ANKRD10,CAMK2N2,AREG,DNM1L,PLK2,ZNF367,KPNA2,TTC39C,DDX58,RECQL,RUNX2,PRKAA1,ETV5,RACGAP1,TXNDC9,SAMD9,S100A2,DUSP5,SSX2IP,RALGPS2,PAK2,NEK2,TNFRSF12A,USP1,LRIF1,ULBP2,GAD1,PSMA5,CCDC88A,GFPT1,HPS3,USP31,MICB,OXR1,KIF20B,IFIT3,EGFR,G2E3,FAS,STK17A,SLCO4A1,TMEM30A,ZDHHC20,DCUN1D1,AURKA,NXPH4,CTSA,SEMA3A,IFIH1,ARHGAP11A,HOXB7,FOXM1,S100A11,CAST,IQGAP1,NUF2,BCL2L1,STIL,TNFSF9,SYTL2,IER3,ACAP2,SP100,KIF14,PLK4,LMAN1,RAB27B,FAR1,CKS2,AGPS,LGALS8,FIGNL1,CDC20,NUSAP1,CASP4,DNAJC10,STK38,CORO1C,EFNA5,CTHRC1,DEPDC1,TAB3,CKAP2,ARHGEF7,ARL4C,GDF15,TGFBR1,CHAC2,DSE,SIX4,CKAP5,HDAC9,KIF5B,TOP2A,E2F7,ADORA1,IRAK1,TOX2,TFAP2A,HSPA13,MSH6,ATP2B1,SMC4,NFE2L3,MOB4,HMMR,PLSCR1,ASPM,RC3H2,AK4,COL7A1,KIF11,BORA,RND3,ZMYND19,AMMECR1,NMI,PPP2R3C,CENPE,UBE2C,L1CAM,MELK,ESYT2,USP16,TLL2 |
| 1.634e-07 | -15.63 | WANG_SMARCE1_TARGETS_DN | MSigDB lists | WANG_SMARCE1_TARGETS_DN | 353 | 88 | 17758 | 2588 |
CCNE2,PPP4R4,PNISR,APOO,TAP1,NDC80,RGS20,SOD2,RNF182,FAM198B,KBTBD11,PRR7,FANCI,TACC2,AKR1B1,TWIST1,STEAP3,NTN4,APIP,RP2,OAS3,LOXL1,MYBL1,CYP1B1,MX1,PPIF,TRIM8,LAP3,SLC39A8,OSTM1,PBK,DRAP1,VPS4B,PTGER4,GALNT7,DUSP4,GTF2A2,SFXN1,TRIM9,HPSE,PDLIM3,PLK2,INPP4B,NRG1,GLA,DLAT,PARP12,ERCC6L,GDF15,ISYNA1,S100A2,LBR,LGALS3BP,BMP2K,SAC3D1,SCML1,B3GALNT1,KIAA0895,CTSC,FJX1,OPN3,CD9,SGK1,H2AFY,CD70,TSPAN13,HLA-C,CITED2,CASD1,ATP2B1,FADS2,PRSS23,MRS2,GRTP1,C4orf27,EGFR,RASA1,NMT2,HLA-B,SLCO4A1,CASP7,PRDX3,SCG2,DCK,AURKA,HMGA1,SPCS3,TBC1D4 |
| 1.652e-07 | -15.62 | regulation of mitotic cell cycle | biological process | GO:0007346 | 475 | 113 | 16441 | 2455 |
HECA,DLGAP5,PSME2,CUL4B,CTDSPL,PTTG1,TP53,CUL1,PSME1,BCL2L1,CCNB1,PDGFB,FANCI,IER3,TP73,NPM2,CCND1,PAK6,BTG3,CYP1A1,CCNA2,PSMD1,CTNNB1,DACT1,KIF14,PSMC2,DLG1,CDKN1B,HSPA2,CTDSP2,PLK1,SIRT1,NEK4,TIMP2,PSRC1,AKT1,CDC20,VPS4B,PRKCQ,NUSAP1,RAD17,PKMYT1,ANLN,CDC25C,CDK1,MAP3K6,JADE1,CCNB3,STK26,PLK2,PSMD3,OVOL1,CHMP4B,XRCC3,TMEM8B,MAD2L1BP,GEN1,PSMC1,MIIP,CTDSP1,NKX3-1,TAOK2,CDKN1C,CIT,PSMD7,PSMD10,TOP2A,E2F7,RB1,IGF1R,PTEN,BMP7,FBXO7,PAK2,NEK2,MSH2,BRD7,BUB1,KANK2,ERCC2,PIM1,KNTC1,PSMA5,DUSP1,HES1,ADAM17,ZWINT,PSMB4,WNT10B,RGCC,STRADB,SCRIB,TRIM35,KIF20B,PIM3,BORA,KIF11,PSMA4,EGFR,INSR,TJP3,FGFR2,CDCA5,E2F1,AURKA,PKD2,STK39,FHL1,CENPE,UBE2C,ESPL1,PKIA,FOXA1 |
| 1.695e-07 | -15.59 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | 90 | 33 | 17758 | 2588 |
LMO7,FAM171B,BMF,EPAS1,NUAK1,ERBB2,RND1,TNS3,SESN3,NPNT,CDKL5,N4BP3,AIM1,DRAM1,EGLN3,RAB27B,PARP9,EPB41L5,HPS3,SALL4,NR3C1,PTGER4,UTRN,NPHP3,TMTC2,ALCAM,CRISPLD2,IL1R1,ZNF704,SH3BP4,ZDHHC7,UACA,EFNA1 |
| 1.696e-07 | -15.59 | CELL_CYCLE_GO_0007049 | MSigDB lists | CELL_CYCLE_GO_0007049 | 312 | 80 | 17758 | 2588 |
CCNE2,ACVR1,DLGAP5,NDC80,TP53,CUL1,KIF2C,CNTROB,CCND1,NPM2,CDKN2C,BTG3,CCNA2,DLG1,CDKN1B,TUBG1,KIF22,CDKN2D,HSPA2,CKS2,PLK1,CDC20,NUSAP1,RAD17,PKMYT1,ANLN,CDC25C,SESN1,MADD,MAP3K11,KPNA2,TMEM8B,MAPK12,USH1C,CDKN1C,CIT,HERC5,KIF23,RACGAP1,NOTCH2,SAC3D1,CKAP5,DIRAS3,BMP2,RB1,PTEN,BMP7,PRC1,NEK2,CKS1B,BUB1,KNTC1,ERCC2,HEXIM2,CITED2,GFI1,MPHOSPH9,SMC4,REC8,SUN2,ZWINT,PAPD7,RUNX3,KIF11,CDK5R1,RHOB,CDK5RAP1,DHRS2,CDCA5,SH3BP4,ARAP1,E2F1,AURKA,CENPE,NDE1,UBE2C,ESPL1,AHR,USP16,RAD21 |
| 1.752e-07 | -15.56 | purine nucleotide binding | molecular function | GO:0017076 | 1837 | 349 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,AURKB,RAB2B,ARF4,ULK2,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,CNGA1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,PDE11A,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,TMEM173,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,TRANK1,RALB,FICD,PDE4D,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,PRKAR1A,GALK1,HSP90B1,TAOK2,ATP9A,ARL4C,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,RAPGEF2,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,ST13,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PSMC2,PAPSS1,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,PSMC1,RRAGD,PRKAA2,RUNX2,LMTK3,BVES,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,AHCY,PIM1,ABCC1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,PINK1,DYRK3,TOR4A,SHPRH,CIT,GNAL,GNE,ERCC6L,TGFBR1,KIF5B,TOP2A,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,MYO5A,ATP2B1,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,RAP2C,UBE2D2,GEM,UBE2C,HIPK3,ABCG1 |
| 1.760e-07 | -15.55 | TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | 422 | 101 | 17758 | 2588 |
ACVR1,UGP2,PAPSS2,RPS6KA1,DGKA,ETNK1,ERBB2,TESK2,PDGFRL,MAPK4,FLT3,DDR1,CDS1,DAPK2,RPS6KA2,PAPSS1,DLG1,PIK3CA,PLK4,PHKA2,MAP3K3,NEK4,PLK1,MARK1,RIPK2,AKT1,ACVR1C,PFKFB2,PBK,TEP1,ROR1,XRCC6BP1,MAP3K6,STK17B,CDK1,PRIM1,PTK7,LIMK1,AXL,STK38,MYLK,MAP3K11,MAPK13,PDXK,ITPKA,CHPT1,MAPK12,GALK1,TAOK2,PINK1,CIT,DGKQ,GNE,TGFBR1,TRIB2,MERTK,NRP2,IGF1R,IRAK1,ARSG,PFKL,PAK2,SGK3,MAP3K9,PRKCI,NEK2,SGK1,MAPK11,PIM1,ERBB3,MAP3K7,PIKFYVE,MAPK7,DGKG,PHKG2,CASK,TESK1,MAPKAPK3,MPP1,STRADB,EIF2AK1,PDK3,ILK,EGFR,DGKE,CDK5R1,TXK,STK17A,MAPKAPK2,INSR,UAP1,ACVRL1,DCK,PRPS2,NR4A3,MPP2,RYK,MAP3K5,HIPK3,RPS6KA3,DMPK |
| 1.767e-07 | -15.55 | Signaling by the B Cell Receptor (BCR) | REACTOME pathways | R-HSA-983705 | 198 | 58 | 8202 | 1235 |
TNRC6C,NFKBIE,PSME2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,CUL1,RASGRP3,PSME1,ITPR2,PHLPP1,PDGFB,FGF19,SH3KBP1,CALM2,PDGFA,PSMD1,PTEN,PIK3AP1,STIM1,CD22,PLCG2,PSMC2,PIK3CA,CDKN1B,TRPC1,PIK3CD,ERBB3,MAP3K7,SYK,RASGRP1,PSMA5,PSMB4,AKT1,NR4A1,CASP9,PIK3R1,CALM1,AGO4,ITPR3,CBL,PSMA4,EGFR,BCL10,IRS2,PLCG1,FYN,FGFR2,PSMD3,PHLPP2,NFKBIA,FGF18,ITPR1,NRG1,PSMC1,GAB1 |
| 1.786e-07 | -15.54 | TOOKER_GEMCITABINE_RESISTANCE_DN | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_DN | 120 | 40 | 17758 | 2588 |
ANXA3,LASP1,HSP90B1,PAPSS2,IGFBP6,DHPS,CTSB,SOX9,SPR,SLC20A1,ERP29,APLP2,ADD3,MLPH,DPYSL2,PDIA6,TIAM1,SLC35A1,LAMP2,PDGFC,CD55,MLEC,AGPS,LPGAT1,EZR,RHOB,CYB5A,STK17A,ACYP1,PLOD2,H1F0,P4HA2,WWTR1,SH3BP4,TRIOBP,STK39,FHL1,ATP6V1C1,PLIN3,HSPB1 |
| 1.883e-07 | -15.49 | positive regulation of cellular metabolic process | biological process | GO:0031325 | 2864 | 518 | 16441 | 2455 |
ACACB,TRIM24,TRIM5,PNPLA2,DNAJC3,HEXB,RET,XIAP,NRG2,IL18,MORF4L2,SNX9,CARD10,PHF1,GRM5,TP73,NPM2,CALM2,PSMD1,DNM2,NEK4,SMARCA2,VPS11,TNIP1,SPRTN,TFAP2C,PRKAR2B,F12,RNF19B,ARF4,PIAS3,PLCG1,MID1IP1,ANKRD6,NOD2,MAP3K11,HDAC1,RNASEL,HSPB1,E2F8,GAB1,HOXC13,ITGA6,SOX9,LMNA,ELF3,TFAP4,NEK2,MAP3K9,MYDGF,NCAM1,MAPK7,NUP85,PHKG2,SALL4,MAPKAPK3,STAT4,PYM1,FHL2,MYBL2,CALCRL,ELK1,ILK,TP53INP2,PSMA4,PLIN5,NCOA3,FNTA,ETS2,SEMA4D,SETD3,AURKA,STK39,GDF11,RPS6KA3,TMEM173,XDH,GRHL2,PRKACA,CCND1,ST5,CDH1,SP100,RASGEF1A,ETV4,PSRC1,RIPK2,FZD4,PFKFB2,CDCA2,PXYLP1,GTF2A2,EBF2,NFIX,IRS2,WFS1,WWTR1,ARNT,MAPK12,TNRC6C,NKX3-1,TAOK2,CKAP2,TRAF2,SDC4,FLOT1,PKN1,ETS1,GSTP1,NFAT5,ICAM1,PDCD10,IRAK1,CTSC,KNDC1,MCF2L,CST3,BAX,PLEKHF1,MAPK11,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,ABLIM2,TXK,PITX2,ATXN7L3,NR1D2,ACVRL1,NR4A3,HMGA1,CENPE,OSR1,CD81,USF2,SHOX2,FOXA1,AGRN,EPAS1,CNOT8,EPHA4,ARFGEF1,NENF,HDAC6,PDGFB,SPTB,FANCI,TFAP2E,PCNA,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,ELF5,PASK,MITF,TNFRSF18,MYBL1,ZNF462,PLK1,THRB,PCGF5,CITED4,NFE2L1,EZR,EAF2,CDK1,VCP,KDM4D,KLF12,PRKCDBP,MAFF,PRKAA2,RUNX2,DNAJB2,RASA2,PSMD7,SORBS3,FBLN1,BMP2,RB1,DAZAP1,IGF1R,GATA2,PAK2,MDFIC,PIM1,WNT3A,PSMA5,RGMB,STRADB,SCRIB,BCL2L13,CDK5R1,MAPKAPK2,CSF1,NLRC5,CTBP1,RAD21,AVPI1,UPF3B,FOXM1,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,LPIN3,EMP2,STIL,BCAP31,PDGFA,LMO4,PLCG2,BCL6,CDH3,NOTCH3,EGLN3,DVL2,CTH,SIRT1,CLCN3,TIMP2,TCEB2,AKT1,CDC20,SERTAD3,PTGS2,RBL1,PSMD3,EFNA5,IRF7,CNEP1R1,PINK1,CD63,TAB3,DAP,GNAL,PSMD10,GDF15,HMGN3,PARM1,GBX2,GTF2F2,TFAP2A,TRIM21,SYK,CAMK2G,P2RX4,NFE2L3,HES1,RHOA,PSMB4,HMGN5,NR3C1,PLAUR,PPARA,PRICKLE1,MAML2,BCL10,DDAH1,BANK1,FGF18,NMI,E2F1,PPP2R3C,PKD2,NDFIP1,UBE2C,ACVR1,TXN,LGR4,GATA3,CUL1,PSME1,CAMK1D,SEPT4,CCNB1,PICK1,PAK6,HELZ2,CTGF,ZFP36,FOSB,IL31RA,PIK3CA,IRF2,ACVR1C,CASP9,AURKB,SAV1,LDB2,POR,AHRR,AREG,TBX1,PLK2,PPP2R4,F2RL1,TRAF5,DDX58,KLF2,SCOC,CDKN1C,PRKAA1,PSIP1,MECOM,CALR,CYR61,DAPK1,GPR161,SOCS5,MFI2,MMD,CALM1,PIP4K2C,WHSC1,KCTD20,CYFIP2,KDM3A,NFIB,RASA1,FAS,PRKAG2,SERTAD2,PELI2,ARAP1,PIAS2,NR4A2,EFNA1,MAP3K5,IRF1,SPRED1,DLGAP5,ARMCX3,IQGAP1,RPS6KA1,THRA,FLT3,EPM2A,CCNA2,RALB,CDKN1B,DAB2IP,OSBPL7,MED30,FOXJ2,SLC11A2,PRKCQ,PYGO1,FZD7,FYN,PPP2R5A,JAK1,STK26,NGFRAP1,STAT1,KIAA1804,SLC27A1,NRG1,KLF5,ATMIN,PRKAR1A,PCOLCE,PBX3,FGF19,SIX4,TEAD3,WWP2,E2F7,RNF128,PTEN,ERBB3,ERCC2,MAP3K7,CITED2,SPRY2,TRIM62,MSH6,NCOA2,PDGFC,RASGRF1,CASK,TEF,FURIN,VAMP3,YES1,FOS,GPLD1,CRTC2,PRDX3,FGFR2,RYK,GRIN2D,LRRK1,GPER1,FZD5,ESPL1,USP16,JARID2,RGMA,CCNC,CASP3,CAMKK1,ERP29,EPCAM,HSF2,GRHL1,DLG1,ASH2L,ARNT2,SLC39A10,RASGRP1,SOD1,TRIM8,ASXL1,EDNRA,SEC14L2,MDK,GPRC5B,MADD,CAB39,PSMC1,NR2C2,PIFO,PPP1R12A,BVES,ETV5,CALM3,TEC,DUSP5,EBF4,PRKCI,FNIP1,BRAT1,NPTN,CCDC88A,MDFI,ELK3,PDE5A,EGFR,BCAR3,GNAS,ONECUT1,NUDT16,INSR,PLPP3,NFKBIA,DCUN1D1,SH3BP4,JAK3,RARG,TOB1,PROM2,DRD1,KLF7,PAX6,SORBS1,IL15,PSME2,OSR2,SS18,KIF14,SMO,TWIST1,ZBTB49,ECE1,NFKB2,F2R,HSPA2,CHP1,FRS3,UPF3A,SOAT1,MAP3K3,BAG4,CD40,MAP3K6,HSF4,JADE1,STAT6,SPTBN5,AKNA,ABCA1,GLIS3,ANXA3,ARHGEF11,SH3D19,TGFBR1,TRIB2,TOP2A,IRF2BPL,CARD8,ADORA1,BMP7,TOX2,BRD7,IQGAP3,ADAM17,DCAF6,WNT10B,GCLC,NR4A1,RGCC,RUNX3,MPV17L2,CASP7,RAP2C,TADA2B,ARRB1,ZMIZ1,SOX8,AHR |
| 1.962e-07 | -15.44 | SH3 | prosite domains | PS50002 | 201 | 59 | 11866 | 1802 |
BIN1,LASP1,SORBS1,PACSIN2,TRIP10,ARHGEF7,SH3D19,RUSC2,UBASH3B,EPS8,MPP5,SORBS3,TEC,CACNB4,SNX9,ARHGEF16,SH3KBP1,EPS8L2,SH3RF2,SH3D21,ARHGAP42,NOXA1,ARHGEF37,SNX18,MCF2L,PLCG2,DLG1,MAP3K9,OSTF1,CTTN,PACSIN1,DLG3,NEB,DOCK4,CASK,MPP1,PIK3R1,SPATA13,YES1,DOCK5,BCAR1,MAPK8IP1,ARHGEF26,RASA1,TXK,PLCG1,ARHGEF19,FYN,TJP3,SH3BP4,SH3GLB2,KIAA1804,MAP3K11,MPP2,ARHGAP4,ARHGEF9,RUSC1,NGEF,ARHGEF4 |
| 1.972e-07 | -15.44 | purine ribonucleotide binding | molecular function | GO:0032555 | 1827 | 347 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,AURKB,RAB2B,ARF4,ULK2,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,CNGA1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,PDE11A,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,TMEM173,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,TRANK1,RALB,FICD,PDE4D,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,PRKAR1A,GALK1,HSP90B1,TAOK2,ATP9A,ARL4C,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,RAPGEF2,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PAPSS1,PSMC2,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,PSMC1,RRAGD,PRKAA2,RUNX2,LMTK3,BVES,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ABCC1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,PINK1,DYRK3,TOR4A,CIT,SHPRH,GNAL,GNE,ERCC6L,TGFBR1,KIF5B,TOP2A,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,MYO5A,ATP2B1,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,RAP2C,UBE2D2,GEM,UBE2C,HIPK3,ABCG1 |
| 2.004e-07 | -15.42 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | 194 | 56 | 17758 | 2588 |
GRN,GAA,SORT1,ARAP3,CD63,HEXB,EFHD2,FAM198B,MGST2,ARHGEF40,GSTP1,SIRPA,ICAM1,LMNA,ARHGEF10L,GNS,ZYX,CST3,DAPK1,H2AFY,IL17RA,SGK1,RAB20,CTSD,TIAM1,NAGA,LAMP2,CPD,TIMP2,MCTP1,ALDH2,ERMAP,MAPKAPK3,MPP1,PLAUR,PYGL,DOCK5,ULK2,CRISPLD2,GABARAPL1,ALDH3B1,SCARB2,MID1IP1,RBM47,HPSE,ZDHHC7,ARRB1,PLXND1,GLA,REEP4,NDFIP1,SLC31A2,SLC27A3,CPPED1,RRAGD,PCSK5 |
| 2.037e-07 | -15.41 | CTTTGT_V$LEF1_Q2 | MSigDB lists | CTTTGT_V$LEF1_Q2 | 1862 | 347 | 17758 | 2588 |
TRIM24,VANGL1,GRIK2,TSC22D3,ATP8A1,CUL1,LGI3,MORF4L2,VASH1,FAM101B,LTBP3,CALM2,SESN3,RGS3,PRICKLE3,KLF3,SERINC2,KCNS3,ATRNL1,CLDN4,PIK3CD,WBP4,TIAM1,SMARCA2,SH3BGRL,SERTAD4,BNIP3L,PRKAR2B,LDB2,ZFAND5,COL12A1,SLC44A3,PGF,ANKRD10,PLCG1,CAMK2N2,MPRIP,WDR11,PLK2,NKD1,MAP3K11,SERPINI1,TMOD2,STARD13,RTN3,CDK17,CDKN1C,NOTCH2,TFAP4,SH3D21,RAC2,FRY,CYR61,VASN,FLRT3,ZIC5,PPP4R1,DAPK1,FBXL14,MAST4,TMED2,GPR161,SOCS5,DNAI1,SPATA20,MMD,KIAA1841,KIF20A,TBC1D8B,CALM1,DCHS1,NPC2,CYFIP2,TP53INP2,KDM3A,DPYSL4,NFIB,RHOB,AP1AR,MPP2,NR4A2,EFNA1,MAP3K5,EHD1,KIF3C,CCDC109B,GRHL2,KCTD12,IL13RA1,BCL2L1,FAM91A1,EGR3,SNN,APC2,DDR1,KTN1,C11orf84,CCND1,ST5,RNF220,DACT1,TAX1BP3,DAB2IP,RTKN2,PDE4D,DLG3,ETV4,MYT1,SCN3A,DOCK4,CAPN6,LYRM1,PANK1,COX11,ATP1B1,PYGO1,ITPR3,CBL,SP4,FZD7,NIN,NFIX,OSBPL2,FYN,CCDC149,PPP1CB,NRG1,NR3C2,IER5L,CTHRC1,FARP1,MPZL1,IGFBP6,RBM24,BIK,EPS8,ARL4C,CDCA3,PBX3,PKN1,HOXB2,EFNB1,SIX4,NEO1,WWP2,SCML1,CTNNBIP1,AKIRIN1,PDCD10,ADD3,ITGB8,PPP1R10,CALD1,TMEM62,GPC3,MCF2L,FUT8,FJX1,SGK3,MAPK11,ERBB3,CITED2,SPRY2,TGIF1,PDGFC,CASK,BCL9,TEF,PIK3R1,GRIN1,FOS,PITX2,RGS9,PLOD2,NR4A3,GRIN2D,HMGA1,FHL1,OSR1,SHOX2,FOXA1,RGMA,ARFGEF1,NDRG2,F11R,MPP5,VARS2,TEX2,SDC1,KREMEN1,CHPF,NKAIN3,RAB15,PCNA,HSF2,CTNNB1,SHC3,DPYSL2,MKRN3,TSPAN6,ELF5,MITF,SLC44A1,ANKRD12,MYH14,ANO4,BTBD3,CYP1B1,CXXC5,ROR1,PTGFRN,CLCN2,SEC14L2,DPYSL3,MDK,CXXC4,HS6ST1,ARHGEF19,KLF12,GPRC5B,WIPI1,MAP2,HOXA9,LEMD1,RRAGD,LASP1,USH1C,PPP1R12A,ZCCHC24,CALM3,RAB6A,FAM81A,FBLN1,PGAP1,IGF1R,LRRN2,GATA2,FAM20C,FRAS1,PIM1,NTN1,WNT3A,GAD1,PSMA5,CKAP4,DPYSL5,ELK3,PCDH1,GYLTL1B,ZSCAN12,C3orf58,RANBP9,CDK5R1,G2E3,BCAR3,FECH,TSC1,PVRL2,H1F0,PAPD5,SLC2A6,ALPK3,ATP1B3,CDAN1,SEMA3A,AFAP1,RARG,TOB1,KLF7,CCNE2,NCKAP5,PAX6,HOXB7,DGKA,TP53,P2RX7,CCNL1,FAM198B,BAHD1,PCBP1,SS18,KCTD15,SRPX,TACC2,LMO4,PPME1,LHX6,REEP1,BCL6,CDH3,VAT1,GLB1L2,NOTCH3,F2R,SLC39A8,ERBB2IP,DUSP4,PTPRJ,PTK7,EFNA5,C1orf43,CTDSP1,GLIS3,SORT1,TAB3,ARHGEF7,GABRG2,TGFBR1,TRIB2,HMGXB4,XPR1,PPP2R3A,NRP2,GBX2,CCDC92,FOXP2,MDM1,ADORA1,LYPD6,TOX2,ZDHHC13,TFAP2A,TRIM3,H2AFY,TSPAN13,DUSP1,SUN2,PSMB4,HMGN5,CRIP2,CCDC34,STMN3,FXR2,MAP1B,ARHGAP24,RND3,PRCP,RAP2C,FIBCD1,PPP2R3C,CEP41,ZMIZ1,NDFIP1,L1CAM,ZBTB33,PKIA,ARHGEF4 |
| 2.045e-07 | -15.40 | Signaling by Interleukins | REACTOME pathways | R-HSA-449147 | 311 | 81 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,INPP5D,ERBB2,NRG2,CUL1,RASGRP3,IL18,PSME1,PDGFB,PRKACA,SPTB,CALM2,PDGFA,PSMD1,SHC3,IL6ST,PSMC2,PIK3CA,DUSP10,DAB2IP,PIK3CD,NFKB2,RASGEF1A,IL1RAP,RASGRP1,FRS3,MAP3K3,RIPK2,DUSP4,CBL,SOCS3,IRS2,FYN,JAK1,PPP2R5A,PSMD3,STAT1,MAP3K11,NOD2,NRG1,SPTBN5,PPP2R5D,PSMC1,INPPL1,TAB3,RASA2,PSMD7,CALM3,PSMD10,TEC,FGF19,DUSP5,ITGA2B,IRAK1,ERBB3,MAP3K7,NCAM1,SYK,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,YES1,PELI3,PSMA4,EGFR,RASA1,IL1R1,FGFR2,PELI2,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.054e-07 | -15.40 | V$SP1_Q6_01 | MSigDB lists | V$SP1_Q6_01 | 228 | 63 | 17758 | 2588 |
KLF2,LASP1,INPPL1,UGP2,PPM1J,IQGAP1,RHBDL3,DGKA,CALM3,SEPT4,TIPRL,KTN1,NFAT5,EPS8L2,XPR1,CALM2,FLII,APLP2,VASP,RABEP2,LLGL2,FAM160A2,SLC46A1,FOSB,SERINC2,ANKRD12,CNNM4,ADAM15,KANK2,TAGLN2,ECE1,NOTCH3,MAPK7,CAMK2G,ABCC1,CPD,CYP26B1,ACBD5,ADAM17,SHMT1,DRAP1,LYRM1,CALM1,PDIK1L,MAP3K6,RAB2B,CDK5R1,IRX3,PGF,PIAS3,DUOX1,PVRL2,CORO1C,MAP3K11,AGBL5,NXPH4,PGM2L1,PITPNA,KLF5,KLF11,C1orf43,STARD13,HOXC13 |
| 2.094e-07 | -15.38 | REICHERT_MITOSIS_LIN9_TARGETS | MSigDB lists | REICHERT_MITOSIS_LIN9_TARGETS | 28 | 16 | 17758 | 2588 |
HMMR,PLK1,CENPA,KIF20A,ASPM,KIF23,CDCA2,NUSAP1,KIF2C,CCNF,CCNB1,G2E3,TOP2A,CALD1,AURKA,CENPE |
| 2.188e-07 | -15.33 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | 1359 | 264 | 17758 | 2588 |
ACVR1,TXN,HSPG2,MRPS15,MORF4L2,OAT,CHST2,PSMD1,DNM2,TFG,METAP2,SMARCA2,SH3BGRL,DSTN,CDYL,BNIP3L,PRKAR2B,SAV1,ICMT,TP53I3,ARF4,SGPP1,KDSR,WDR11,GDE1,DNM1L,ATP7B,HDAC1,F2RL1,RTN3,ALDH6A1,AKAP17A,TXNDC9,ISYNA1,PSIP1,LMNA,GNS,FLII,RAC2,RANBP1,FBXO7,PPP4R1,DAPK1,MSH2,USP1,KCTD3,TMED2,MCCC2,TRAK2,PIGC,FADS2,PMPCB,STAT4,FHL2,SRSF5,MEST,ILK,PCTP,PSMA4,RASA1,FAS,SCARB2,SLCO4A1,FNTA,ETS2,SEMA4D,MATN2,MDH1,GDF11,MAP3K5,RPS6KA3,EHD1,CEP70,RALBP1,CD82,CAST,ETNK1,BCL2L1,MGST2,KTN1,GNB2,CD46,CDH1,RALB,ACSL4,FLOT2,TMBIM1,AGPS,DRAP1,VPS4B,PRKCQ,RAD17,RAB38,GTF2A2,H2AFV,FZD7,ZMPSTE24,PPP2R5A,ACYP1,NGFRAP1,CORO1C,SLC9A6,INPP4B,PRKAR1A,NUDT6,ARHGEF3,PBX3,GMCL1,PDCD10,OXCT1,KCNK5,ECI2,TAGLN2,CITED2,S100A6,MSH6,TMX1,SMC4,PDGFC,PCCB,B3GNT2,SHMT1,PLSCR1,RAPGEF2,MPP1,EMP3,UBAC1,YES1,DCTN6,DGCR2,PLOD2,CCDC6,PRDX3,AMMECR1,RYK,ACOT7,SRSF9,PHC1,CCNI,CASP3,ST13,CNOT8,HEBP1,CUL4B,F11R,TAF6L,ITPR2,HDAC6,MAP1LC3B,TM9SF2,ARL1,PAPSS1,ASH2L,KIF22,RP2,IL1RAP,CERS2,CD55,SOD1,STAU2,ACBD3,PRKRA,MAN2A2,HOXA9,SH3GLB2,CAB39,CTNND1,CHPT1,APBA2,PSMC1,SERPINE2,LRRFIP2,PPP1R12A,PEX6,PSMD7,ASL,B3GALNT1,DAZAP1,TIMP1,GATA2,KCNN4,SRP54,PIM1,NPTN,TMEM8A,ACAD8,HP1BP3,ABCC1,MGAT4B,HMG20B,EIF2AK1,RANBP9,NMT2,FECH,CSF1,DCUN1D1,RAB31,SPAG7,PITPNA,RAD21,UGP2,UPF3B,SOD2,GMPR,SDF4,SS18,WDR44,LMO4,RPN2,LMAN1,MINPP1,F2R,GM2A,EBAG9,SEPHS1,UPF3A,CTH,SIRT1,CPD,BAG4,AKT1,SLC39A8,ACO1,GLO1,MRPS35,ERBB2IP,PDHX,DAG1,ATP1A1,IDE,ALDH5A1,PSMD3,PEX2,GCLM,CMAS,PACSIN2,CD63,BLVRB,PSMD10,LBR,VPS26A,ITGA2B,MDM1,BRD7,HSPA13,WBP5,GCLC,GGH,CAPNS1,LEPR,DDX23,PRDX4,TWSG1,HNRNPH2,SPINT2,RAP2C,NMI,UBE2D2,PGRMC1,FAM117A,ARRB1,ACADM,NDFIP1,AHR |
| 2.205e-07 | -15.33 | Adaptive Immune System | REACTOME pathways | R-HSA-1280218 | 668 | 148 | 8202 | 1235 |
KLC2,TAP1,FBXO2,UBE2Z,NRG2,UBE2Q1,CUL1,PSME1,KIF2C,ITPR2,PJA2,PDGFB,KIF26A,SPSB1,SH3KBP1,CALM2,PSMD1,AP1M2,STIM1,PSMC2,PIK3CA,DNM2,TRPC1,KIF22,PIK3CD,RASGRP1,ERAP2,ITCH,CASP9,AGO4,RNF19B,TRIM9,PLCG1,RAP1GAP,PPP2R5D,PSMC1,GAB1,MRC2,NFKBIE,SEC61G,HLA-E,HLA-F,PSMD7,ASB9,KIF23,CALM3,RACGAP1,PHLPP1,CALR,VASP,UBE2Q2,PIK3AP1,CD22,PAK2,PRKG1,HLA-C,CTSD,PSMA5,KIF20A,MICB,CALM1,PSMA4,EGFR,RASGRP2,PVRL2,PHLPP2,NFKBIA,ITPR1,CTSA,FBXO27,KIF3C,PSME2,INPP5D,ERBB2,RASGRP3,RNF182,CD274,PRKACA,PDGFA,RNF220,CDH1,PLCG2,CDKN1B,LGMN,SEC23A,SEC61B,AKT1,RIPK2,TCEB2,CDC20,PRKCQ,ASB13,ITPR3,CBL,CD40,SOCS3,IRS2,TAPBP,FYN,PTPRJ,PPP2R5A,PSMD3,NRG1,TNRC6C,KLHL13,CTSB,PDIA3,SELL,PSMD10,FBXO6,FGF19,HLA-A,ICAM1,KIF5B,DTX3L,PTEN,CTSC,UBE2J1,KLC3,TRIM21,WWP1,ERBB3,MAP3K7,SYK,PSMB4,NR4A1,PIK3R1,UBE2A,YES1,KIF11,BCL10,DCTN6,CTSL,HLA-B,CD8A,FGFR2,TRIM69,FGF18,CTSV,UBE2D2,ERAP1,FBXO44,ITGAV,CENPE,ICOSLG,CD81,UBE2C,CD33 |
| 2.223e-07 | -15.32 | parotid | COSMIC cancer mutations | parotid | 594 | 132 | 17775 | 2585 |
TNK1,ACVR1,SLC25A13,RET,PDGFRL,BAIAP3,SPTB,WEE1,RPS6KA2,PQLC2,CTNNB1,PAPSS1,DLG1,PIK3CA,SEMA3G,PIK3CD,TFG,CCDC74A,NEK4,SMARCA2,PBK,AURKB,PRKRA,LCP1,FASTKD1,PLK2,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,HOXC13,MRC2,CDK17,CHCHD7,DOCK11,APBA1,RB1,IGF1R,PFKL,DAPK1,MAP3K9,KNTC1,PIM1,PIKFYVE,MAPK7,USP31,ADCK3,PIP4K2C,EIF2AK1,KIAA1109,PDK3,EGFR,MAPKAPK2,DCK,DYSF,AURKA,SAMD8,MAP3K5,JAK3,RPS6KA3,DMPK,MFSD3,RPS6KA1,TP53,ETNK1,DGKA,ERBB2,GRK6,PRKACA,DDR1,FLT3,APPBP2,CDK14,MUC16,EPHB4,DLG3,MYT1,SCYL3,SEPHS1,FRS3,MYO5B,MAP3K3,AKT1,RFK,CAPN6,ATP1B1,MAP3K6,FYN,JAK1,CDK19,AXL,STK38,PTK7,KLF5,PDXK,LIFR,PRKAR1A,MAPK12,PINK1,GNE,FAM134A,SLC25A36,NEO1,CEP97,IRAK1,PTEN,CDK16,MGAT4A,CKS1B,SGK1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,SUN2,B3GNT2,CASK,PIK3R1,ZKSCAN2,AK4,MAML2,LRRC1,YES1,MAPK8IP1,DCAF10,BTG1,CCDC6,FGFR2,TBC1D4 |
| 2.251e-07 | -15.31 | TTGTTT_V$FOXO4_01 | MSigDB lists | TTGTTT_V$FOXO4_01 | 1950 | 361 | 17758 | 2588 |
ACVR1,HSPG2,GRIK2,TSC22D3,PNPLA2,CACNA2D2,CUL1,IL18,SEPT4,CMTM6,GRM5,PAK6,CDKN2C,SESN3,RGS3,IL31RA,KLF3,FOSB,KCNS3,TUBG1,CRY2,PIK3CD,MANF,PPP1CA,ARMCX6,WBP4,TIAM1,SMARCA2,SPATA18,SNTB2,SH3BGRL,LDB2,ZFAND5,PNKD,ULK2,NKD1,MYLK,EIF4EBP2,STARD13,E2F8,PDPR,CDK17,MRC2,FRMD4A,NFKBIE,CDKN1C,ADO,RAB23,C6orf106,ISYNA1,APBA1,TNFRSF19,MECOM,GNS,TFAP4,SH3D21,ITGA3,RALGPS2,FRY,SNX18,CYR61,ZNRF2,SLC16A6,FLRT3,BDH1,ZIC5,NCAM1,MAST4,GCC2,KIAA1841,KIF20A,WHSC1,KIF20B,KDM3A,DPYSL4,NFIB,RHOB,DHX32,NT5C2,PRKAG2,SLC4A4,ETS2,CSNK1G1,PELI2,ITPR1,C1orf21,AGBL5,SFMBT1,NR4A2,EFNA1,IFIH1,HOOK1,EHD1,DOCK9,CCDC109B,GRHL2,REPS2,DDIT4L,THRA,NDRG1,RHBDL3,RGS20,IRX4,RNF182,IL13RA1,BLCAP,FAM91A1,ZNF385B,EPM2A,ZFYVE9,APPBP2,C11orf84,APLP2,RNF220,ST5,DACT1,CDKN1B,ACSL4,PDE4D,ETV4,SCN3A,DOCK4,NRBF2,LYRM1,SAT1,CLSTN1,DNAJB14,AKR1E2,ITPR3,H2AFV,ATP10D,SP4,FZD7,EBF2,GABARAPL1,NFIX,OSBPL2,POPDC3,PDLIM3,CORO1C,SIPA1L1,PPP1CB,NRG1,SLC27A1,KLF5,NR3C2,OTUD5,IER5L,IGFBP6,MPZL1,GCAT,BIK,CBLL1,PBX3,CYB561,ZNF219,SEPP1,ETS1,SRPX2,EFNB1,NEO1,SCML1,ITGB8,PPP1R10,ANKS1B,MGAT4A,GPC3,ERBB3,CITED2,TGIF1,LONRF3,DENND1B,BCL9,NUB1,PIK3R1,C2orf69,LRRC1,GPLD1,PITX2,CRTC2,RGS9,BTG1,SLC35B3,ABCB1,NR4A3,SHOX2,JARID2,UGT8,ARFGEF1,MCCC1,F11R,DNER,PDGFB,KREMEN1,HTR1D,BTG3,PCNA,CTNNB1,CDKL5,TSPAN6,IL6ST,MITF,SLC44A1,ELF5,POF1B,NTN4,TLN2,BTBD3,PCGF5,TRIM8,MARK1,CXXC5,HN1L,ASXL1,CBX6,RGAG1,EAF2,PRKRA,CXXC4,TBC1D17,KLF12,HOXA9,TRIM45,CTNND1,LEMD1,RBM43,APBA2,MAFF,HS6ST3,NR2C2,RMND5A,RUNX2,BMF,ZNF395,CHCHD7,ETV5,SORBS3,RAB6A,PHLPP1,DOCK11,DHRS3,IL18R1,IGF1R,GATA2,PRKCI,PIM1,NTN1,PLCB2,CKAP4,ABCC1,DPYSL5,MGAT4B,C3orf58,RANBP9,MUM1L1,G2E3,PRX,GNAS,XKRX,TSC1,INSR,KBTBD2,PLD1,SEMA3A,SHROOM2,TOB1,KLF7,RAD21,LZTFL1,PAX6,SORBS1,HOXB7,DGKA,TP53,MORC4,RASGRP3,CYP26A1,SYTL2,PER2,RAD23A,PDGFA,WDR44,LMO4,PPME1,BCL6,TWIST1,DIXDC1,FAR1,HSPA2,SULF2,EBAG9,SEPHS1,MAP3K3,TAF5,KIAA0040,PTPRU,SERTAD3,ERBB2IP,DUSP4,CDC25C,PAFAH1B3,STAT6,TLE1,VSIG10,C1orf43,BIN1,CDS2,SORT1,DYRK3,CPEB4,KLHL13,GNE,MCTP2,FAM134A,GABRG2,HMGN3,COL4A5,INTS8,PPP2R3A,SIRPA,NRP2,IL22RA1,HDAC9,CCDC92,FOXP2,CEP97,ADORA1,FAM63A,TFAP2A,GTF2F2,SGK1,H2AFY,TSPAN13,CLIP2,FAM134C,RBMS2,DUSP1,WBP5,NFE2L3,SUN2,MOSPD2,NR3C1,NR4A1,AMFR,CRIP2,AKAP3,TCEAL8,MAP1B,CD83,PRDX4,CNOT2,DDAH1,FAT4,PGRMC1,FAM117A,HOXB13,GRAMD1C,CEP41,NDFIP1,PKIA,GOLGB1 |
| 2.318e-07 | -15.28 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP | 190 | 55 | 17758 | 2588 |
SUN1,TXN,DLGAP5,LGALS3,GNPDA1,NDRG1,DAP,RACGAP1,KIF2C,LACTB2,MNS1,REPS1,KCTD9,TOP2A,CDKN2C,CCNA2,PRC1,PLK4,CD9,CKS1B,KIF22,BUB1,AK3,SNX10,PSMA5,TMED2,LAMP2,CENPA,PQLC3,SH3BGRL,S100A4,CDC20,LITAF,NUSAP1,PRRC1,CCNF,ZFAND5,IDH1,KIF11,CDC25C,CDK1,PSMA4,GABARAPL1,TMEM50B,CARHSP1,CASP7,IDE,TWSG1,CORO1C,DBI,CDCA5,HDAC1,KPNA2,GEM,CCNB2 |
| 2.403e-07 | -15.24 | kinase regulator activity | molecular function | GO:0019207 | 150 | 47 | 16491 | 2452 |
CCNE2,CCNC,CASP3,SPRED1,NKX3-1,CDKN1C,IBTK,IQGAP1,DNAJC3,CALM3,CCNL1,TRIB2,GSTP1,CALM2,CDKN2C,CCND1,RAC2,PAK2,PIK3CA,CKS1B,H2AFY,CDKN1B,HEXIM2,ERBB3,CDKN2D,SPRY2,CKS2,CHP1,CALM1,PIK3R1,RGCC,PRKAR2B,MAPK8IP1,CDK5R1,BCL10,SOCS3,CDK5RAP1,PRKAG2,CAMK2N2,GPRC5B,MADD,CAB39,EFNA5,NRG1,HSPB1,PKIA,PRKAR1A |
| 2.418e-07 | -15.24 | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | 195 | 56 | 17758 | 2588 |
GRN,LAMP1,FARP1,MRC2,SORT1,NFKBIE,UGP2,SLC2A8,CPT2,SDC4,ABCG2,NDRG2,FTH1,RASGRP3,MRAS,CTSZ,NANS,CENPN,ARHGEF10L,PDGFA,ATP6V0B,DNPEP,FAM46A,CTSC,RALB,PLCG2,CAPG,ADCK2,CD9,TACSTD2,CTTN,WBP4,CTSD,SPRY2,CKAP4,CPD,PDGFC,LOC81691,CDA,PYGL,PRKAR2B,RAB38,BLVRA,STX3,CD83,FUCA1,PRDX3,PRCP,CSF1,RAB31,NR4A3,MAOA,SLC31A2,ANXA11,ACOT7,CD33 |
| 2.467e-07 | -15.22 | ribonucleotide binding | molecular function | GO:0032553 | 1843 | 349 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,AURKB,POR,RAB2B,ARF4,ULK2,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,CNGA1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,PDE11A,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,TMEM173,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,TRANK1,RALB,FICD,PDE4D,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,PRKAR1A,GALK1,HSP90B1,TAOK2,ATP9A,ARL4C,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,RAPGEF2,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PSMC2,PAPSS1,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,PSMC1,RRAGD,PRKAA2,RUNX2,LMTK3,BVES,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ABCC1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,UGP2,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,PINK1,DYRK3,TOR4A,SHPRH,CIT,GNAL,GNE,ERCC6L,TGFBR1,KIF5B,TOP2A,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,MYO5A,ATP2B1,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,RAP2C,UBE2D2,GEM,UBE2C,HIPK3,ABCG1 |
| 2.548e-07 | -15.18 | Ser/Thr_kinase_AS | interpro domains | IPR008271 | 309 | 79 | 18293 | 2672 |
ACVR1,CAMKK1,RPS6KA1,MAPK4,GRK6,CAMK1D,PRKACA,CDK14,DAPK2,WEE1,RPS6KA2,CDKL5,PASK,STK35,PLK1,NEK4,MARK1,AKT1,RIPK2,ACVR1C,PBK,PRKCQ,PKMYT1,AURKB,MAP3K6,CDK1,ADRBK2,STK17B,ULK2,CDK19,STK38,PLK2,MYLK,KIAA1804,MAP3K11,PRKAA2,DYRK3,PINK1,CDK17,TAOK2,NUAK1,CIT,PRKAA1,TGFBR1,PKN1,BMP2K,ADRBK1,IRAK1,CDK16,PAK2,PRKG1,MAP3K9,NEK2,DAPK1,SGK3,PRKCI,SGK1,BUB1,PIM1,MAPK7,MAP3K7,MAST4,PHKG2,CAMK2G,MAPKAPK3,EIF2AK1,PIM3,PDIK1L,STK17A,MAPKAPK2,ACVRL1,CSNK1G1,AURKA,CDK18,MAP3K5,HIPK3,RPS6KA3,MELK,DMPK |
| 2.552e-07 | -15.18 | GSE25087_TREG_VS_TCONV_FETUS_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_FETUS_UP | 181 | 53 | 17758 | 2588 |
GOLIM4,ARAP3,LGALS3,EPAS1,FRMD6,NDRG1,LRP4,ERI2,DHRS3,FAM46C,CMTM6,NFAT5,SDF4,KIAA1147,PLS3,APLP2,CYP1A1,PIK3AP1,DPYSL2,TMEM62,TOX2,PPP4R1,TWIST1,TNFRSF18,KLF9,STT3B,CTTN,PIM1,DLG3,SNX10,MMD,BTNL9,AMFR,ATP1B1,DOCK5,PCTP,TRUB1,SGPP1,KLHL2,IRS2,HLF,NETO2,RAB11FIP1,PGM2L1,PKD2,KLF11,HS3ST3B1,ATP1B3,AKIP1,GLCCI1,AHR,FAM45A,RAD21 |
| 2.552e-07 | -15.18 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 181 | 53 | 17758 | 2588 |
CD99,FARP1,FOXM1,TUBB4B,VANGL1,MTL5,KIF2C,GPSM2,NUP62CL,BARD1,PSIP1,NAPG,CCNA2,PTEN,KCNK5,KIF14,KIF13B,PPME1,PLK4,CKS1B,GOT1,KIF22,RFX5,RNASEH2A,GFI1,MPHOSPH9,MSH6,CKS2,WBP5,SOCS5,TIMP2,AGPS,TACC1,MPP1,CORO2A,LYRM1,WHSC1,EZR,SLC11A2,GGH,LRRC1,H2AFV,IDH1,ADRBK2,DGKE,PGRMC1,DHTKD1,PKD2,PLXND1,CENPE,NCAPG2,CBX5,DLAT |
| 2.618e-07 | -15.16 | circulatory system development | biological process | GO:0072359 | 774 | 167 | 16441 | 2455 |
CASP3,GAA,ACVR1,HSPG2,EPAS1,GATA3,IL18,CCNB1,VASH1,PDGFB,TYMP,PCNA,TGFBR3,RPS6KA2,CTNNB1,CTGF,PIK3CA,TIPARP,CPE,CYP1B1,SMARCA2,ASXL1,LOXL2,SAV1,ZFAND5,EDNRA,PGF,HS6ST1,HPSE,TBX1,TRAF3IP1,MYLK,UNC5B,E2F8,GAB1,PCSK5,SCN5A,BVES,SOX9,NOTCH2,NCKAP1,DHRS3,LMNA,MECOM,CALR,BMP2,ITGA3,CYR61,GATA2,MEGF8,FLRT3,TNFRSF12A,MYDGF,WNT3A,TMED2,ELK3,SALL4,DCHS1,FHL2,CALCRL,WHSC1,EPHA1,NPHP3,ILK,GNA11,C3orf58,RHOB,RASA1,MOSPD3,TSC1,INSR,ITGA7,PLPP3,ALPK3,EGFL7,EFNA1,EGLN1,TCF25,PAX6,GRHL2,FOXM1,IRX4,PKP2,COL18A1,ERBB2,EGR3,STIL,PDGFA,NOV,SETDB2,LMO4,SMO,GYS1,TWIST1,DAB2IP,NOTCH3,EPHB4,ECE1,LOXL1,DVL2,SIRT1,MAP3K3,AKT1,FZD4,SAT1,HTATIP2,SOCS3,PTGS2,PTPRJ,PDLIM3,PNPLA6,KLF5,NRG1,PLXND1,PRKAR1A,NKX3-1,ADGRG1,CCM2,TGFBR1,ETS1,SRPX2,FGF19,NRP2,GBX2,SGPL1,HDAC9,E2F7,PDCD10,OXCT1,ITGB8,ADRBK1,PTEN,GPC3,BAX,ADAM15,ACTA2,ERBB3,MAP3K7,CITED2,SGCB,SYK,POU6F1,HES1,NR4A1,RAPGEF2,PPARA,FOXL1,GPLD1,PITX2,ARHGAP24,LEMD2,FAT4,ACVRL1,SCG2,FGFR2,PRCP,TBX18,FGF18,ERAP1,PKD2,HOXB13,ITGAV,ZMIZ1,OSR1,FZD5,SHOX2,AHR |
| 2.618e-07 | -15.16 | cardiovascular system development | biological process | GO:0072358 | 774 | 167 | 16441 | 2455 |
CASP3,GAA,ACVR1,HSPG2,EPAS1,GATA3,IL18,CCNB1,VASH1,PDGFB,TYMP,PCNA,TGFBR3,RPS6KA2,CTNNB1,CTGF,PIK3CA,TIPARP,CPE,CYP1B1,SMARCA2,ASXL1,LOXL2,SAV1,ZFAND5,EDNRA,PGF,HS6ST1,HPSE,TBX1,TRAF3IP1,MYLK,UNC5B,GAB1,E2F8,PCSK5,SCN5A,BVES,SOX9,NOTCH2,NCKAP1,DHRS3,LMNA,MECOM,CALR,BMP2,ITGA3,CYR61,GATA2,MEGF8,FLRT3,TNFRSF12A,MYDGF,WNT3A,TMED2,ELK3,SALL4,DCHS1,FHL2,CALCRL,WHSC1,EPHA1,NPHP3,ILK,GNA11,C3orf58,RHOB,RASA1,MOSPD3,TSC1,INSR,ITGA7,PLPP3,ALPK3,EGFL7,EFNA1,EGLN1,TCF25,PAX6,GRHL2,FOXM1,IRX4,PKP2,COL18A1,ERBB2,EGR3,STIL,PDGFA,NOV,SETDB2,LMO4,SMO,GYS1,TWIST1,DAB2IP,NOTCH3,EPHB4,ECE1,LOXL1,DVL2,SIRT1,MAP3K3,AKT1,FZD4,SAT1,HTATIP2,SOCS3,PTGS2,PTPRJ,PDLIM3,PNPLA6,KLF5,NRG1,PLXND1,PRKAR1A,NKX3-1,ADGRG1,CCM2,TGFBR1,ETS1,SRPX2,FGF19,NRP2,GBX2,SGPL1,HDAC9,E2F7,PDCD10,OXCT1,ITGB8,ADRBK1,PTEN,GPC3,BAX,ADAM15,ACTA2,ERBB3,MAP3K7,CITED2,SGCB,SYK,POU6F1,HES1,NR4A1,RAPGEF2,PPARA,FOXL1,GPLD1,PITX2,LEMD2,ARHGAP24,FAT4,ACVRL1,SCG2,FGFR2,PRCP,TBX18,FGF18,ERAP1,PKD2,HOXB13,ITGAV,ZMIZ1,OSR1,FZD5,SHOX2,AHR |
| 2.672e-07 | -15.14 | cell division | biological process | GO:0051301 | 458 | 109 | 16441 | 2455 |
CCNE2,SPC25,ACTR8,PTTG1,NDC80,CCNO,NUF2,BCL2L1,CNTROB,KIF2C,CCNB1,SEPT4,SNX9,CDK14,CCND1,WEE1,CCNA2,SETDB2,CNTRL,RALB,KIF14,DIXDC1,PPP1CA,CKS2,PLK1,NEK4,PSRC1,SEPT6,CDC20,VPS4B,NUSAP1,KIF13A,CDCA2,AURKB,CCNF,ANLN,CDC25C,CDK1,FZD7,CCNB3,WWTR1,TRIOBP,PPP1CB,CHMP4B,ARF6,RGS14,SGOL1,REEP4,PPP2R2D,ANXA11,ZC3HC1,ARHGEF11,CKAP2,KLHL13,CIT,ETV5,ERCC6L,CDCA8,CDCA3,KIF23,RACGAP1,SPDL1,TEAD3,CKAP5,SAC3D1,TOP2A,RB1,SNX18,LLGL2,CENPJ,PRC1,NEK2,CKS1B,BUB1,KNTC1,ERCC2,WNT3A,SMC4,ZWINT,RHOA,CENPC,KIF20A,PAPD7,TACC1,PARD3B,ASPM,DIAPH2,KIF20B,SKA1,BCAR1,KIF11,BORA,RHOB,RASA1,FAM64A,FGFR2,CDCA5,PAPD5,FAM83D,AURKA,CENPE,NUP37,NDE1,NCAPG2,UBE2C,CCNB2,ESPL1,USP16,RAD21 |
| 2.680e-07 | -15.13 | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN | 186 | 54 | 17758 | 2588 |
ARHGEF3,PARP12,VANGL1,PSME2,CYP2J2,CENPI,PTTG1,CDCA3,TAP1,UBE2Q1,HERC5,RASGRP3,PSME1,SAMD9,HERC6,LGALS3BP,HDAC9,CAPN2,CEP97,SP100,TRIM21,IFIT1,SEMA3G,OAS3,FAR2,LAMP3,LAMP2,REC8,MX1,PPIF,B3GNT2,MMD,PLSCR1,LAP3,USP18,EIF5A2,SAT1,FHL2,DUSP4,IFIT3,FAS,HLA-B,TAPBP,CASP7,NMI,PRPS2,C1orf21,STAT1,RAB11FIP1,PIAS2,IRF7,CENPE,IFIH1,IFI6 |
| 2.680e-07 | -15.13 | GSE27786_BCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_BCELL_VS_NKCELL_DN | 186 | 54 | 17758 | 2588 |
PLEKHG3,GSDMD,ACVR1,FRMD4A,PPM1J,PLEKHJ1,DNAJC3,DSE,MAP1LC3B,SLC25A35,SDF4,B3GALNT1,TNS3,GATA2,RALB,IL6ST,ABCD1,KLF9,MARCH2,ALPK1,NCEH1,SPRY2,MCCC2,FARP2,CASK,MCTP1,CITED4,PQLC3,PLSCR1,TNIP1,RGMB,GUSB,OSTM1,OXR1,VAMP3,EMP3,KIF13A,PRKRA,TNS4,TMEM50B,MID1IP1,RBM47,STAT6,DBI,PLA2G15,NLRC5,ARRB1,ADIPOR1,CHMP4B,LRRK1,ZMIZ1,RTN3,ISOC1,CTDSP1 |
| 2.717e-07 | -15.12 | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | MSigDB lists | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | 100 | 35 | 17758 | 2588 |
ARHGAP11A,DLGAP5,FOXM1,TSC22D3,PTTG1,KIF2C,CCNB1,SLC20A1,IER3,CCNA2,CTGF,FOSB,BCL6,ACTA2,CKS1B,NOTCH3,DUSP1,HES1,CENPA,CDC20,AURKB,CCNF,FOS,CDK1,SLC25A4,HTT,NFKBIA,AURKA,NR4A2,CENPE,ZMIZ1,UBE2C,CCNB2,CD81,COL16A1 |
| 2.800e-07 | -15.09 | GSE10325_MYELOID_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_MYELOID_VS_LUPUS_MYELOID_DN | 191 | 55 | 17758 | 2588 |
LAMP1,CDS2,CCDC109B,TXN,PARP12,IL15RA,CD63,GNPDA1,PSME2,ADO,TAP1,GMPR,DHX8,CALM3,HERC5,CUL1,HERC6,LGALS3BP,HLA-A,CALM2,SP100,TRANK1,SLC16A6,SRP54,IFIT1,KLF9,PIM1,CTSD,TFG,GM2A,KDELR1,MX1,ADAM17,PLSCR1,LAP3,SLC39A8,MICB,DRAP1,USP18,CALM1,TNS1,IFIT3,SNTB1,SPTLC2,NUCB1,CASP7,SEMA4D,NMI,STAT1,IRF7,CTSA,PLIN3,IFIH1,IFI6,SRSF9 |
| 2.808e-07 | -15.09 | microtubule-based process | biological process | GO:0007017 | 517 | 120 | 16441 | 2455 |
GAS2L1,CFAP74,DYNLRB1,KIF3C,SPC25,DLGAP5,AK7,TUBB4B,KLC2,NDC80,XIAP,CNTROB,KIF2C,ZMYND10,KIF26A,STIL,KTN1,TTC21B,WEE1,SS18,LRRC6,CTNNB1,TACC2,DNAH6,KIF14,DLG1,PLK4,TUBG1,KIF22,RASGRP1,TUBA4A,DNAAF3,CHP1,PLK1,SPEF2,CAMSAP3,SOD1,PSRC1,CENPA,KIFC2,CELSR2,CAPN6,FIGNL1,FOPNL,UXT,VPS4B,KIF1C,EZR,NUSAP1,KIF13A,AURKB,CDK1,DAG1,NIN,MAP2,PLK2,TRAF3IP1,PPP2R4,MAP3K11,RGS14,SGOL1,COPG1,PPP1R12A,KIF23,RACGAP1,GPSM2,RAB6A,SPDL1,APBA1,IFT27,DNAH3,SSX2IP,LMNA,CKAP5,KIF5B,RB1,LLGL2,CENPJ,KIF13B,TBCD,TUBGCP6,PRC1,NEK2,KLC3,SLAIN2,SPRY2,RPGR,TTLL1,DNAI1,GCC2,SUN2,RHOA,LCA5,KIF20A,CFAP46,TACC1,ASPM,MYBL2,SPA17,STMN3,KIF20B,NPHP3,KIF11,BBS2,RANBP9,SPAG1,MAP1B,DCTN6,HTT,WDR19,AURKA,PKD2,PPP2R3C,SSNA1,CENPE,KIF12,NDE1,WDR62,ESPL1,FBXW5 |
| 2.858e-07 | -15.07 | seminoma | COSMIC cancer mutations | seminoma | 726 | 155 | 17775 | 2585 |
LTBP1,TNK1,ACVR1,TMEM41B,CAMKK1,EPHA4,RET,CAMK1D,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,NEB,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,PRKAR2B,ROR1,AURKB,IDH1,ADRBK2,STK17B,ABR,ULK2,PLCG1,PLK2,LIMK1,MYLK,MAP3K11,BMP1,MAPK13,RNASEL,SPRY4,PRKAA2,CDK17,DHPS,PRKAA1,ADCK5,MERTK,PDXDC1,BMP2K,IGF1R,NEK2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,MYLIP,KCTD3,PHKG2,ABCC1,ADCK3,TESK1,STRADB,WHSC1,EIF2AK1,PDK3,PDIK1L,RANBP9,EGFR,STK17A,MAPKAPK2,INSR,ALPK3,AURKA,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,TCF25,TRIP10,RPS6KA1,TP53,TESK2,ERBB2,RHPN2,GRK6,PRKACA,DDR1,FLT3,CDK14,SP100,PLK4,EPHB4,SCYL3,MAP3K3,RIPK2,AKT1,PRKCQ,PKMYT1,CBL,MAP3K6,EPHA10,DUOX1,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,MAPK12,PINK1,TAOK2,DYRK3,TGFBR1,PKN1,TRIB2,DSE,KCNC4,SNTA1,TMEM87B,ADRBK1,IRAK1,LLGL2,PTEN,CDK16,TUBGCP6,CD9,SGK3,SGK1,H2AFY,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,MYO5A,CASK,ASPM,YES1,TXK,FAT4,FGFR2,ACVRL1,PRCP,NEIL3,RIN3,WDR91,HIPK3,MELK |
| 2.862e-07 | -15.07 | NAGASHIMA_EGF_SIGNALING_UP | MSigDB lists | NAGASHIMA_EGF_SIGNALING_UP | 56 | 24 | 17758 | 2588 |
HES1,NR4A1,EGR3,PHLDA1,FOS,DUSP5,IER3,BCL10,ETS2,CTGF,CYR61,AREG,KBTBD2,ZFP36,NAB2,FOSB,NR4A3,NR4A2,TNFRSF12A,GEM,TIPARP,F2RL1,MAFF,DUSP1 |
| 2.911e-07 | -15.05 | MODULE_105 | MSigDB lists | MODULE_105 | 196 | 56 | 17758 | 2588 |
WASF3,FOXM1,DAP,FXYD3,COL18A1,CCNB1,SLC20A1,ERP29,WEE1,PCNA,CCNA2,CTGF,MGAT1,CYR61,RGS3,LMO4,PSMC2,PPP4R1,NEK2,DNM2,MSH2,CKS1B,TUBG1,ACTA2,CDH3,KNTC1,CITED2,S100A13,ATP2B1,CKS2,CYP1B1,PIGC,CENPA,MMD,MAPKAPK3,COG2,LPGAT1,FURIN,MYBL2,PYGL,GGH,CCNF,ITPR3,ALCAM,CDK1,KIAA0141,PAFAH1B3,KCNK1,FAM3C,SERPINB5,PDXK,HSPB1,AHR,CSRP2,ACOT7,MELK |
| 2.917e-07 | -15.05 | REACTOME_IMMUNE_SYSTEM | MSigDB lists | REACTOME_IMMUNE_SYSTEM | 891 | 184 | 17758 | 2588 |
SIGIRR,UNC93B1,TXN,KLC2,TAP1,FBXO2,UBE2Z,UBE2Q1,CUL1,IL18,PSME1,KIF2C,ITPR2,PJA2,KIF26A,SPSB1,SH3KBP1,CALM2,AP1M2,PSMD1,NUP210,RPS6KA2,STIM1,IL6ST,PSMC2,PIK3CA,DNM2,IRF2,KIF22,PIK3CD,IL1RAP,RASGRP1,CD55,USP18,CASP9,CDK1,TRIM9,PLCG1,NOD2,MAPK13,KPNA2,RNASEL,RAP1GAP,PPP2R5D,PSMC1,DDX58,INPPL1,MRC2,NFKBIE,LGALS3,SEC61G,HLA-F,ASB9,PSMD7,KIF23,CALM3,RACGAP1,PHLPP1,CALR,VASP,UBE2Q2,PIK3AP1,PAK2,PRKG1,HLA-C,CTSD,NCAM1,MAPK7,ULBP2,NUP85,PSMA5,KIF20A,MAPKAPK3,CALM1,IFIT3,ELK1,PSMA4,RASGRP2,MAPKAPK2,IL1R1,PVRL2,PELI2,NFKBIA,NLRC5,CTSA,FBXO27,JAK3,IFIH1,IFI6,RPS6KA3,IRF1,KIF3C,NLRX1,PSME2,RPS6KA1,P2RX7,RNF182,RASGRP3,CD274,BCL2L1,PRKACA,CD46,RNF220,CDH1,SP100,PLCG2,CDKN1B,IFIT1,OAS3,LGMN,NFKB2,MAP3K3,MX1,SEC23A,SEC61B,TCEB2,RIPK2,AKT1,CDC20,PRKCQ,DUSP4,CBL,ASB13,ITPR3,CD40,CASP4,SOCS3,IRS2,FYN,JAK1,PPP2R5A,DDOST,PSMD3,STAT1,IRF7,MAPK12,OTUD5,HSP90B1,TAB3,KLHL13,CTSB,TRAF2,PSMD10,SELL,HERC5,PDIA3,FBXO6,HLA-A,ICAM1,KIF5B,DTX3L,IRAK1,PTEN,CTSC,UBE2J1,KLC3,TRIM21,MAPK11,WWP1,MAP3K7,CNPY3,SYK,ADAM17,PSMB4,IFITM3,NR4A1,PIK3R1,UBE2A,PELI3,YES1,KIF11,FOS,BCL10,DCTN6,HLA-B,CD8A,UBE2D2,ERAP1,FBXO44,ITGAV,ICOSLG,NUP37,UBE2C,CD81 |
| 2.942e-07 | -15.04 | E2F3_UP.V1_UP | MSigDB lists | E2F3_UP.V1_UP | 177 | 52 | 17758 | 2588 |
CCNE2,UGT8,PLSCR4,ENO2,FAM92A1,CDKN1C,LRP4,EPHX4,ABCG2,FAM78A,CHST2,CYP26A1,SAC3D1,IL17RB,CDKN2C,LRRC45,E2F7,PCNA,ZDHHC12,REEP1,ZDHHC23,KCNS3,ATRNL1,SNX10,TIAM1,GAD1,HSPA2,RASGRP1,TAF5,FBXL16,MICB,CDK5R1,CD83,MMP15,DDAH1,RTN4RL1,DHRS13,CDK19,DCK,ZFP30,HOXA9,ZNF367,SLC4A3,KIAA1804,RHOBTB2,TMOD2,PLXND1,CMPK2,SLC27A3,EGLN1,NGEF,RRAGD |
| 2.942e-07 | -15.04 | GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | MSigDB lists | GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | 177 | 52 | 17758 | 2588 |
HSP90B1,DLGAP5,FOXM1,CENPI,PTTG1,PDIA5,DNAJB11,RASGRP3,NUF2,CHAC2,CCNB1,TMEM19,SDC1,PARM1,ATG4A,KIF14,BHLHE41,PHTF1,SLC44A1,UBE2J1,TUBG1,SRP54,RPN2,BUB1,MANF,LMAN1,ITM2C,HMMR,SEC61B,ERLEC1,ZWINT,PBK,CDC20,TMEM133,GGH,NUSAP1,EAF2,KIF11,CDK1,MUM1L1,GPLD1,PRDX4,TRAM2,WFS1,AURKA,B4GALT3,GLCCI1,CCNB2,GEN1,E2F8,MELK,DENND5B |
| 2.962e-07 | -15.03 | cell-substrate adhesion | biological process | GO:0031589 | 164 | 50 | 16441 | 2455 |
BCAM,SORBS1,TAOK2,CD63,BVES,ITGA6,ARHGEF7,TESK2,SORBS3,MICALL2,DDR1,MERTK,EMP2,ITGA2B,EPDR1,LYPD5,ZYX,ITGA3,MUC4,CTNNB1,ITGB8,CTGF,NPNT,LYPD3,KIF14,ADAM15,TNFRSF12A,CTTN,TIAM1,SNED1,EPB41L5,SGCE,RHOA,FBLN5,FZD4,VAMP3,EPHA1,ILK,ANTXR1,DAG1,FZD7,TSC1,HPSE,COL13A1,ITGA7,AXL,ITGAV,TMEM8B,EFNA1,AKIP1 |
| 2.963e-07 | -15.03 | adenocarcinoma | COSMIC cancer mutations | adenocarcinoma | 17602 | 2580 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,NKX3-1,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,MCF2L,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ABRACL,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,PMPCB,DDB2,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,S100A11,TMEM217,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ASCL5,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,ATP5H,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,RHBDL3,PTTG1,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,NR4A3,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,VPS26A,PARM1,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,GPR107,CAPN12,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,CEP41,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PLEKHJ1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,PXDC1,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 3.102e-07 | -14.99 | anatomical structure formation involved in morphogenesis | biological process | GO:0048646 | 974 | 202 | 16441 | 2455 |
CASP3,CFAP74,ACVR1,UGT8,HSPG2,EPAS1,AK7,RET,CCNO,GATA3,IL18,MPP5,VASH1,TYMP,TGFBR3,LRRC6,CTGF,CTNNB1,STIM1,ELF5,ALDH1A3,PIK3CA,CYP1B1,DNAAF3,SPEF2,CELSR2,FOPNL,CASP9,TFAP2C,LOXL2,COL12A1,EDNRA,IRX3,DZIP1L,PGF,HS6ST1,HPSE,TBX1,TRAF3IP1,HDAC1,TMOD2,UNC5B,E2F8,ITGA6,SOX9,RAB23,NCKAP1,DUSP5,SSX2IP,VASP,ITGA3,CYR61,FAM20C,OCRL,COL6A1,TNFRSF12A,MYDGF,PIKFYVE,WNT3A,TTLL1,DNAI1,EPB41L5,ELK3,B9D2,SALL4,CEP89,FHL2,CALCRL,KIF20B,SCRIB,EPHA1,ILK,NFIB,RHOB,CDK5R1,GNAS,MMP15,TSC1,ONECUT1,ETS2,PVRL2,HTT,ITGA7,WDR19,EGFL7,EFNA1,RARG,EGLN1,EHD1,NF2,GRHL2,TCTN2,LFNG,ST14,CAST,TP53,COL18A1,ZMYND10,EGR3,PRKACA,STIL,EXT2,PDGFA,NOV,LMO4,SMO,BCL6,CNNM4,TWIST1,DAB2IP,NOTCH3,EPHB4,NFKB2,SNX10,DVL2,SIRT1,SAT1,HTATIP2,DUSP4,TANC1,NFIX,CEP162,ARHGAP35,PTGS2,SHROOM3,PTK7,PNPLA6,KLF5,PLXND1,COBL,PRKAR1A,TTC8,CTHRC1,TNRC6C,NKX3-1,ADGRG1,POC1B,SDC4,TGFBR1,ETS1,SRPX2,SIX4,PPP2R3A,NRP2,FZD6,GBX2,NEO1,CAPN2,CD109,E2F7,PDCD10,PTEN,KNDC1,BMP7,FJX1,TFAP2A,BAX,CD9,ATP8B1,ADAM15,ERCC2,MAP3K7,CITED2,SYK,RPGR,DUSP1,TGIF1,ADAM17,WNT10B,FMN1,CFAP46,NR4A1,PPARA,PRICKLE1,COL7A1,RAB3IP,BBS2,SPAG1,GPLD1,BCL10,CNOT2,CNTNAP1,LEMD2,ARHGAP24,PROM1,TWSG1,ACVRL1,SCG2,FGFR2,PRCP,FGF18,TBX18,SPINT2,NR4A3,ERAP1,HOXB13,ITGAV,SOX8,OSR1,FZD5,CEP41,FOXA1 |
| 3.167e-07 | -14.97 | ZHENG_BOUND_BY_FOXP3 | MSigDB lists | ZHENG_BOUND_BY_FOXP3 | 470 | 109 | 17758 | 2588 |
TTC39B,IBTK,CAST,NDC80,ETNK1,GATA3,ITPR2,FAM91A1,GRK6,CACNB4,KBTBD11,FLT3,FAM46C,SNX9,SH3KBP1,SP100,IL6ST,KLF3,BCL6,CDKN1B,IRF2,TMEM64,CPE,IL10RB,MGAT5,SPEF2,SGCE,PSRC1,ASXL1,AGPS,SYNE2,UTRN,PTGER4,PRKCQ,PRKAR2B,IDH1,SESN1,STK17B,LCP1,KDSR,ENPP1,PLCG1,FYN,JAK1,CDK19,RBL1,AXL,LRIG1,INPP4B,NFKBIZ,LTA4H,GLCCI1,F2RL1,MAMDC2,KLF2,ARHGEF3,CDK17,UBASH3B,MAN1A2,ITGA6,SELL,TRIB2,ETS1,PGAP1,PRRG4,PARM1,RB1,SPP1,CEP97,ADD3,SLC35B4,ECI2,MDFIC,TSPAN13,CNGA1,CNOT6L,CITED2,ATP2B1,FAM69A,FBLN5,B3GNT2,ELK3,STAT4,PIK3R1,MRS2,LRRC66,PGBD1,RAB3IP,HEATR5A,IFIT3,KDM3A,FAS,FRMD4B,CNOT2,NCOA3,RCBTB2,SLC35B3,FAM3C,ZDHHC20,NR4A3,PIAS2,DTX4,NR4A2,ATP1B3,MAP3K5,TBC1D4,AHR,ESYT2,JARID2 |
| 3.232e-07 | -14.94 | IGARASHI_ATF4_TARGETS_DN | MSigDB lists | IGARASHI_ATF4_TARGETS_DN | 88 | 32 | 17758 | 2588 |
PACSIN2,PRKAA1,ETNK1,NCKAP1,DOCK11,FZD6,PER2,CDS1,NOV,DDHD2,OPN3,SLC35B4,KCNS3,POF1B,SORL1,SOAT1,OSTM1,TMTC2,NEURL1B,LEPR,SFXN1,CDK19,PVRL2,GNPTAB,FAM3C,ARRB1,PGM2L1,RAP1GAP,PRR15,RPS6KA3,FAM134B,DENND5B |
| 3.241e-07 | -14.94 | GSE7852_TREG_VS_TCONV_THYMUS_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_THYMUS_DN | 187 | 54 | 17758 | 2588 |
EXPH5,ANKRD13D,ATP8A1,MAN1A2,ELOVL7,ARL4C,LGI3,FAM78A,ZNRF3,TMEM170B,GRK6,HDGFRP2,FAM101B,SLC20A1,KREMEN1,DENND2D,FZD6,RABGGTA,TMEM63A,B3GALNT1,OTUD1,ZCCHC12,ZFP36,CYP2S1,MITF,SRR,SGK1,FAM102A,CNGA1,MAP3K7,MYLIP,ALS2CL,CTDSP2,SLC16A5,SCN3A,HCN3,P2RX4,LOC81691,PCCB,HPS3,TIMP2,PFKFB2,NPC2,F12,TANC1,XKRX,KCNMB4,GPRC5B,RCBTB2,SLC9A6,C1orf21,RAP2C,APPL2,CTBP1 |
| 3.243e-07 | -14.94 | NGF signalling via TRKA from the plasma membrane | REACTOME pathways | R-HSA-187037 | 355 | 89 | 8202 | 1235 |
SPRED1,PSME2,RPS6KA1,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,RPS6KA2,RALB,SHC3,PSMC2,PIK3CA,DNM2,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,MAPK13,NRG1,SPTBN5,PSMC1,GAB1,PPP2R5D,PRKAR1A,MAPK12,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,MAPK11,ERBB3,NCAM1,MAPK7,PSMA5,CAMK2G,DUSP1,RASGRF1,RHOA,PSMB4,MAPKAPK3,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,ELK1,PSMA4,RASA1,EGFR,MAPKAPK2,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3,RPS6KA3 |
| 3.375e-07 | -14.90 | GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP | 192 | 55 | 17758 | 2588 |
SPC25,CEP70,DEPDC1,DLGAP5,WDTC1,C5orf30,MPP5,INTS8,ETS1,REPS1,SSX2IP,APPBP2,E2F7,NAPG,RGS12,NEK2,ATRNL1,USP1,DLG3,RNF26,MSH6,SMC4,WBP5,METAP2,TRAK2,PLK1,FADS2,SSH3,ALDH2,AKT1,PBK,MBNL3,EZR,PDE5A,NUSAP1,LRRC1,C3orf58,CYB5A,PAFAH1B3,UEVLD,RCBTB2,TTC12,NETO2,ZNF704,FAM117A,AURKA,ETAA1,DMWD,LSM14B,REEP4,PPP2R5D,TOB1,E2F8,ZBTB33,PHC1 |
| 3.375e-07 | -14.90 | WELCSH_BRCA1_TARGETS_UP | MSigDB lists | WELCSH_BRCA1_TARGETS_UP | 192 | 55 | 17758 | 2588 |
ADD1,IQGAP1,HEXB,GATA3,PBX3,NDUFA4,HMGN3,TXNDC9,KIF2C,RAB6A,SEPP1,TOP2A,CD46,EPCAM,KIF5B,ADD3,TM9SF2,CD9,ACTA2,TMBIM6,WWP1,HMGCL,ALDH7A1,CITED2,TRAM1,NDUFA12,TMED2,CKS2,HMMR,SEC23A,AGPS,NR3C1,MICB,VAMP3,SRSF5,NPC2,IDH1,ALCAM,KIF11,MYL12A,CDK1,GALNT3,DDOST,JAK1,KCNK1,H1F0,PRCP,NAT1,STAT1,PGRMC1,HDAC1,ARF6,SERPINB1,RPS6KA3,PRKAR1A |
| 3.375e-07 | -14.90 | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | 192 | 55 | 17758 | 2588 |
ARHGAP11A,CASP3,SPRED1,FARP1,SPC25,SERPINE2,ST14,UBASH3B,NDRG1,SERPINB9,BARD1,SNX9,CHST2,TMCC3,EPDR1,TOP2A,EPCAM,RCN1,CD109,RNF128,NPNT,TACC2,PRC1,PLK4,KIF22,STT3B,IQGAP3,GFI1,C12orf75,TMBIM1,GCNT1,LAMP2,PCGF5,PBK,CORO2A,LPGAT1,LITAF,BTBD19,CKAP2L,KIF20B,C4orf27,FRMD4B,KIAA0141,TWSG1,GNPTAB,ZNF367,FAM3C,E2F1,INPP4B,NR4A2,PLXND1,CENPE,HOOK1,CD81,KDELC2 |
| 3.376e-07 | -14.90 | TGANTCA_V$AP1_C | MSigDB lists | TGANTCA_V$AP1_C | 1074 | 215 | 17758 | 2588 |
HSPG2,CAMKK1,EPHX4,FBXO2,NDRG2,LGI3,LYNX1,MPP5,SEPT4,LTBP3,SLC35E4,NCS1,SLC9A7,HTR1D,CDKN2C,PAK6,BTG3,PSMD1,SHC3,RGS3,MITF,SERINC2,ABCA2,AKR1B1,CLDN4,NTN4,TINAGL1,MYH14,TLN2,TUBA4A,THRB,ATL1,SMARCA2,TRIM8,MCTP1,MARK1,ASXL1,DSTN,RGAG1,TMEM151A,ZFAND5,TYSND1,TRIM9,TRIM47,TBC1D17,MPRIP,MAP2,KCNK1,MYLK,PRKCDBP,CAB39,STARD13,RTN3,SEMA6B,SCN5A,SCOC,LGALS3,LRRFIP2,NUAK1,CALB2,ETV5,PSMD7,CNTNAP2,FAM81A,DHRS3,S100A2,HPCAL4,PRRG4,LMNA,MECOM,BMP2,SH3D21,VASP,SLC16A6,VASN,RPL39,KCNN4,NECAB3,TNFRSF12A,NPTN,PIM1,PSMA5,IGSF3,MDFI,ELK3,PIP4K2C,KBTBD8,EPHA1,SPTLC2,KDM3A,GLT8D2,PRX,IL1R1,EPN3,C1orf21,S100A5,AGBL5,OSMR,DYSF,EFNA1,DRP2,COL16A1,TOB1,RPS6KA3,XDH,PROM2,WDR63,DMPK,SPRED1,SLC25A24,CAPN12,XYLT1,DGKA,PRSS22,RNF182,FAM198B,FAM91A1,DDR1,PRR7,REPS1,ZNF385B,ZFYVE9,CDK14,FAM46A,LMO4,VAT1,PDE4D,ACSL4,RAB27B,ETV4,SNX10,SEMA3B,TBC1D10B,DOCK4,TMEM43,CAPN6,PTPRU,PFKFB2,SAT1,SYP,IGSF8,ATP1B1,C15orf39,MAP3K6,EBF2,GABARAPL1,PEX5,POPDC3,STAT6,SIPA1L1,STAT1,ADAMTS14,KLF5,RCAN2,NRG1,HS3ST3B1,REEP4,GEN1,COBL,MAMDC2,MAPK12,CTHRC1,CMAS,ENO2,IGFBP6,KLHL13,PKN1,SPR,GSTP1,SRPX2,IL22RA1,NRP2,HDAC9,CD109,SLC25A45,IRAK1,IGSF9,MCF2L,GPC3,GTF2F2,SGK3,ADAM15,SGK1,ABCD1,TAGLN2,KLF9,CNOT6L,GFI1,HCN3,NFE2L3,TGIF1,ARAP2,MLEC,CASK,LONRF3,CTNNAL1,CRB3,DENND1B,PHLDB3,FURIN,EMP3,CAPNS1,COL7A1,AIF1L,TMEM50B,SERPINB5,FAM117A,OTUB2,FBXO44,HMGA1,ATP6V1C1,SHOX2,UBE2C,FOXA1,SNPH |
| 3.425e-07 | -14.89 | immune response-regulating signaling pathway | biological process | GO:0002764 | 562 | 128 | 16441 | 2455 |
UNC93B1,TRIM5,GATA3,CUL1,NRG2,PSME1,ITPR2,CACNB4,PDGFB,SPTB,CALM2,RPS6KA2,PSMD1,ELMO2,SHC3,PSMC2,PIK3CA,PIK3CD,SCARA3,RASGRP1,TNIP1,ITCH,CASP9,CR2,AGO4,PLCG1,LIMK1,NOD2,GAB1,PPP2R5D,PSMC1,DDX58,THEMIS2,RASA2,PSMD7,CALM3,TEC,NCKAP1,PHLPP1,DUSP5,VASP,PIK3AP1,PAK2,MAPK7,NCAM1,PSMA5,MAPKAPK3,MICB,CALM1,CYFIP2,ELK1,PSMA4,EGFR,RASA1,MAPKAPK2,PELI2,PHLPP2,NFKBIA,ITPR1,ARPC2,IFIH1,JAK3,RPS6KA3,SPRED1,PSME2,RPS6KA1,INPP5D,ERBB2,RASGRP3,PRKACA,PDGFA,PLCG2,CDKN1B,DAB2IP,PDE4D,NFKB2,RASGEF1A,LGMN,FRS3,AKT1,RIPK2,PRKCQ,ITPR3,DUSP4,CD40,IRS2,PTPRJ,FYN,JAK1,PSMD3,NRG1,IRF7,SPTBN5,HSP90B1,TNRC6C,TAB3,CTSB,PSMD10,BTN3A1,PLD2,FGF19,IRAK1,PTEN,BAX,MAPK11,ERBB3,MAP3K7,CNPY3,SYK,CAMK2G,RASGRF1,PSMB4,RAPGEF2,NR4A1,PIK3R1,GRIN1,YES1,BCAR1,FOS,GPLD1,BCL10,TXK,CTSL,FGFR2,FGF18,NR4A3,UBE2D2,GRIN2D |
| 3.454e-07 | -14.88 | TGCACTT,MIR-519C,MIR-519B,MIR-519A | MSigDB lists | TGCACTT,MIR-519C,MIR-519B,MIR-519A | 433 | 102 | 17758 | 2588 |
HECA,ACVR1,VANGL1,TMEM217,THRA,EPHA4,TESK2,BLCAP,FAM78A,MAPK4,BAHD1,FAM46C,ZFYVE9,PAK6,WEE1,BTG3,DPYSL2,ENPP5,DNM2,ANKRD12,SNX16,TMEM64,ACSL4,EPB41L4B,MYT1,MAP3K3,LAMP2,TIMP2,CELSR2,ITCH,ERBB2IP,PTGFRN,STK17B,NFIX,ARHGAP35,CAMK2N2,KLF12,LIMK1,STK38,ZNF367,LRIG1,ZNF704,TRIOBP,KLF11,SPRY4,PRR15,ARHGEF11,FRMD6,PRKAA1,HABP4,MIER3,KIF23,NFAT5,EFNB1,DNAJB9,NRP2,M6PR,GNS,RB1,E2F7,CEP97,PPP1R10,CALD1,BHLHE41,FJX1,MAP3K9,TRIM3,SORL1,KLF9,PANX2,CCDC88A,SMC4,ELK3,LPGAT1,SYBU,PIK3R1,WHSC1,FAM73B,YES1,SRSF5,ANKRD29,MAP1B,USP6,ARHGAP24,TMEM50B,SERTAD2,KBTBD2,CSNK1G1,RAP2C,ITPR1,NETO2,E2F1,CLIP4,SFMBT1,PGM2L1,PKD2,MAP3K5,CPEB2,NIPA1,FOXA1,PKIA,FAM45A |
| 3.457e-07 | -14.88 | regulation of cell motility | biological process | GO:2000145 | 666 | 147 | 16441 | 2455 |
ACVR1,ATP8A1,RET,GATA3,PLXNA1,CAMK1D,VASH1,HDAC6,PDGFB,EPCAM,DAPK2,TNFRSF18,TACSTD2,SEMA3G,PIK3CD,CYP1B1,ACVR1C,ARHGDIB,ABR,DPYSL3,PLCG1,MYLK,NKD1,FAM110C,NOD2,HSPB1,F2RL1,GAB1,MIIP,DDX58,SEMA6B,ARAP3,SERPINE2,LGALS3,SOX9,FBLN1,LMNA,SSX2IP,CORO1B,BMP2,CALR,RAC2,ITGA3,TIMP1,IGF1R,CYR61,SORL1,NTN1,EPB41L5,ANO6,SPATA13,KIF20B,EPHA1,ILK,RHOB,EGFR,ONECUT1,AP1AR,INSR,SEMA4D,PLPP3,CSF1,EGFL7,EFNA1,PLD1,CFAP20,SEMA3A,DRD1,NF2,PKP2,COL18A1,CD274,EMP2,PDGFA,SVBP,NOV,SP100,KIF14,DAB2IP,TWIST1,PDE4D,EPB41L4B,F2R,SEMA3B,DOCK4,BAG4,AKT1,PTPRU,DMTN,CCSAP,SYNE2,PTGER4,DOCK5,DAG1,IRS2,PTGS2,PTPRJ,CORO1C,NRG1,PLXND1,ARHGAP4,TCAF1,ANXA3,ADGRG1,ARHGEF7,SDC4,SELL,CBLL1,PLD2,JAG2,PKN1,ETS1,SRPX2,ITGA2B,PPP2R3A,NRP2,ICAM1,HDAC9,CXCL16,PDCD10,ADORA1,PTEN,SGK3,SGK1,ADAM15,CITED2,SUN2,RHOA,ADAM17,MPP1,RAPGEF2,PIK3R1,RGCC,FURIN,BBS2,BCAR1,GPLD1,SWAP70,ACVRL1,PRCP,RAP2C,FGF18,SPINT2,ITGAV,GPER1,ARSB,CD81 |
| 3.459e-07 | -14.88 | FURUKAWA_DUSP6_TARGETS_PCI35_DN | MSigDB lists | FURUKAWA_DUSP6_TARGETS_PCI35_DN | 68 | 27 | 17758 | 2588 |
ARHGAP11A,CCNE2,CENPA,DLGAP5,HJURP,CTNNAL1,CKAP2,PBK,CALB2,RACGAP1,NUSAP1,KIF20B,KIF2C,AURKB,CCNB1,STIL,GOLT1A,KIF11,ETS1,PRIM1,CCNA2,PRC1,DYSF,AURKA,ACOX2,CCNB2,MAFF |
| 3.461e-07 | -14.88 | SANA_TNF_SIGNALING_UP | MSigDB lists | SANA_TNF_SIGNALING_UP | 80 | 30 | 17758 | 2588 |
MX1,CTHRC1,TNIP1,RIPK2,PARP14,OXR1,SAT1,SOD2,FTH1,SLC7A2,ANO9,LGALS3BP,ICAM1,RHOB,HLA-A,KIAA1147,HLA-B,TAPBP,CSF1,NFKBIA,ATP13A3,DRAM1,IFIT1,ITGAV,OAS3,HLA-C,NCEH1,CMPK2,ICOSLG,IFIH1 |
| 3.497e-07 | -14.87 | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN | MSigDB lists | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN | 197 | 56 | 17758 | 2588 |
GAA,FARP1,IL15RA,UBASH3B,PBX3,TGFBR1,TRMT2B,NCKAP1,GALM,BAIAP3,NUCB2,LTBP3,IL17RB,BMP2,ITGA3,FAM160A2,CYP2S1,OSBPL3,KIF13B,CD70,MDFIC,MTMR11,F2R,TRAM1,KANK3,C9orf72,MSH6,GCNT1,LAMP2,LOC81691,TIMP2,S100A4,TFAP2C,PRICKLE1,FAM133B,PRKAR2B,RNF19B,ALCAM,ANKRD29,C3orf58,FRMD4B,AHRR,ENPP1,PTPRJ,KLF12,HPSE,ANKRD6,CSF1,AXL,S100A5,FGD6,CHMP4B,SPCS3,PER3,NIPA1,EHD1 |
| 3.497e-07 | -14.87 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | 197 | 56 | 17758 | 2588 |
SUN1,MAN2B2,KLF2,SIGIRR,UNC93B1,INPPL1,ZNF395,CAST,ATP8A1,INPP5D,SELL,HMGN3,INTS8,MGST2,ERP29,ADD3,NUP210,FAM46A,METTL7A,ZFP36,LMO4,CST3,SORL1,RFX5,MTMR11,PIK3CD,CNPY3,PLCB2,SLC35A1,PGM1,ALDH2,PSRC1,KIAA0040,ADCK3,S100A4,CDA,PYGL,FOS,CRISPLD2,RHOB,RASGRP2,FUCA1,STX10,PELI2,STK38,SECTM1,CCDC69,ZDHHC7,CLMN,KLF11,PIEZO1,LTA4H,NRGN,CHPT1,CPPED1,CD33 |
| 3.515e-07 | -14.86 | MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | 76 | 29 | 17758 | 2588 |
FBLIM1,TGIF1,MBP,UGT8,CDC20,EPS8,PTTG1,CDCA3,UTRN,SLC1A3,CCNB1,IFIT3,SDC1,CDK1,SFXN1,SLC4A4,TIMP1,IRAK1,AREG,PLOD2,BCL6,ACTA2,KIF22,TNFRSF12A,IGFBP2,PER3,LSM14B,F2R,UBE2C |
| 3.515e-07 | -14.86 | SEKI_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | SEKI_INFLAMMATORY_RESPONSE_LPS_UP | 76 | 29 | 17758 | 2588 |
NFKBIE,PLSCR1,TNIP1,RIPK2,SOD2,SLC11A2,EGR3,CD40,CASP4,EGFR,ICAM1,RND1,FAS,IER3,BMP2,BTG1,SLCO4A1,CXCL16,CSF1,PLK2,NFKBIA,OSMR,NFKBIZ,RAB20,RFX5,ICOSLG,NFKB2,PTPRE,MAFF |
| 3.524e-07 | -14.86 | GATTGGY_V$NFY_Q6_01 | MSigDB lists | GATTGGY_V$NFY_Q6_01 | 1110 | 221 | 17758 | 2588 |
EXPH5,LTBP1,MCCC1,DNAJB11,TAF6L,CNTROB,NANS,ITPR2,SEPT4,OAT,NUP62CL,SPTB,WEE1,SESN3,SHC3,STIM1,DPYSL2,RGS3,LMAN2L,OSBPL3,FOSB,PASK,STEAP2,TMEM143,AKR1B1,ANKRD12,DUSP10,IQCD,RP2,MYH14,TECR,ANO4,PXMP4,RNF26,BTBD3,TIAM1,NEB,LAMP2,PLK1,FOPNL,DSTN,C12orf65,CR2,EAF2,LDB2,PNKD,CDK1,TYSND1,VCP,GINS4,IRX3,KDM4D,DOLPP1,PRDM5,AGFG2,HDAC1,EIF4EBP2,TMEM8B,GLA,NRGN,PPP2R5D,E2F8,NR2C2,RMND5A,ALDH6A1,HLA-F,SOX9,ETV5,SLC25A27,ASB9,KIF23,RACGAP1,RAB6A,C3orf18,SH3D21,ICAM5,ZIC5,SLC30A6,MSH2,USP1,RFX5,NPTN,NCAM1,MAPK7,DLX4,RIMS2,CYP26B1,REC8,DPYSL5,UFD1L,MMD,KIF20A,HMG20B,KBTBD8,SPTLC2,TP53INP2,RANBP9,SFXN5,RHOB,MOSPD3,FAM64A,WDR19,SPAG7,ARAP1,AURKA,CDK18,NDE1,PLIN3,PER3,CBX5,IFI6,PROM2,WDR63,DOCK9,ARHGAP11A,AVPI1,PAX6,SPC25,CEP70,NF2,TCTN2,GRHL2,CAST,SUZ12,TESK2,TDRKH,FTH1,BCL2L1,BAHD1,PCBP1,PRKACA,CYP39A1,SLC25A35,C1orf116,ZNF385B,SAP130,CDH1,FICD,LMO4,TNPO2,CDH3,RPN2,GOT1,TWIST1,RNASEH2A,EGLN3,DLG3,ETV4,CKS2,MAP3K3,GCA,BAG4,C6orf1,PSRC1,COQ10B,SERTAD3,SLC11A2,ATP1B1,CD40,CDC25C,ATP10D,PPP2R5A,DDOST,ACYP1,PEX2,TLE1,EFNA5,XRCC3,OTUD5,IER5L,SORT1,NKX3-1,TNRC6C,CPEB4,SLC41A1,CIT,ARHGEF7,PDIA3,PBX3,CRABP2,IFT27,HOXB2,M6PR,TOP2A,KIF5B,CDK16,LLGL2,GPC3,FDXR,FUT8,CKS1B,BUB1,TSPAN13,KLF9,RAG1,C12orf75,TPCN1,TGIF1,RHOA,TEF,BCL9,PIK3R1,TRIM35,FXR2,BORA,FUCA1,PITX2,FGFR2,PRCP,HNRNPH2,DBI,FAM117A,UACA,HOXB13,HMGA1,NUP37,CEP41,UBE2C,ESPL1,JARID2,TLL2 |
| 3.575e-07 | -14.84 | JISON_SICKLE_CELL_DISEASE_UP | MSigDB lists | JISON_SICKLE_CELL_DISEASE_UP | 178 | 52 | 17758 | 2588 |
GAS2L1,MYL9,ANXA3,CDS2,TXN,NFKBIE,IL15,GNPDA1,PSME2,BLVRB,TAP1,CUL1,TP53I11,SNN,ITGA2B,HLA-A,CALR,TYMP,TIMP1,P4HB,IQCE,MITF,CD9,IFIT1,NOTCH3,GM2A,NEK4,LAMP2,MX1,P2RX4,MICB,MPP1,BNIP3L,HTATIP2,EMP3,ATP1B1,BLVRA,IFIT3,SPTLC2,LHFPL2,RHEB,TCN2,PRDX4,ZMPSTE24,NUCB1,CASP7,H1F0,AXL,STAT1,TDRD7,CTSA,PLIN3 |
| 3.601e-07 | -14.84 | protein domain specific binding | molecular function | GO:0019904 | 614 | 137 | 16491 | 2452 |
LAMP1,ST13,GRIK2,EPHA4,GATA3,MPP5,F11R,CNTROB,SLC9A3R2,PICK1,SH3KBP1,CALM2,TGFBR3,ELMO2,CABP1,ARL1,CAPG,DLG1,DNM2,VPS11,SH3BGRL,CASP9,EZR,PRKAR2B,LDB2,VCP,DPYSL3,CXXC4,NKD1,NOD2,SCN5A,INPPL1,RUNX2,LRRFIP2,STRN4,CALM3,RAB6A,APBA1,HPCAL4,VASP,ITGA3,NOXA1,GATA2,PRKCI,OSTF1,WNT3A,EPB41L5,CALM1,KIF20B,SRSF5,ILK,EPN3,INSR,TCEAL4,CABIN1,NDE1,SHROOM2,CTBP1,NF2,IQGAP1,INPP5D,THRA,PTTG1,BCL2L1,REPS1,ARHGEF16,SCNN1A,SP100,TACC2,SH3BP1,KIF14,SRR,DIXDC1,TWIST1,DAB2IP,ESPN,PDE4D,RAB27B,DLG3,DVL2,SIRT1,DOCK4,CLCN3,RIPK2,FZD4,SYP,CBL,CDC25C,DAG1,FZD7,IRS2,ATP1A1,PLXND1,PINK1,NKX3-1,PLSCR4,CIT,DAP,BIK,LBR,AIP,SIRPA,SNTA1,CTNNBIP1,CARD8,LLGL2,PTEN,CENPJ,FUT8,BAX,ADAM15,CITED2,ATP2B1,WBP5,ADAM17,RHOA,PLSCR1,FMN1,GUSB,CRB3,TACC1,RAPGEF2,PLAUR,PPARA,LITAF,STMN3,CARD19,SNTB1,TCEAL8,BCAR1,CNTNAP1,CCDC6,PKD2,SH3BGRL2,OCLN,FOXA1,ARHGEF4 |
| 3.612e-07 | -14.83 | Signaling by VEGF | REACTOME pathways | R-HSA-194138 | 320 | 82 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,CTNNB1,ELMO2,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,DUSP4,ITPR3,IRS2,PGF,PLCG1,FYN,PPP2R5A,JAK1,AXL,PSMD3,MAP3K11,CTNND1,MAPK13,SPTBN5,NRG1,HSPB1,PSMC1,PPP2R5D,MAPK12,WASF3,RASA2,PSMD7,CALM3,PSMD10,NCKAP1,FGF19,DUSP5,NRP2,ITGA2B,PAK2,MAPK11,ERBB3,NCAM1,PSMA5,CAMK2G,DUSP1,RASGRF1,RHOA,PSMB4,MAPKAPK3,RAPGEF2,PIK3R1,CALM1,GRIN1,CYFIP2,BCAR1,PSMA4,RASA1,EGFR,MAPKAPK2,FGFR2,ITPR1,FGF18,ARRB1,GRIN2D,ITGAV,JAK3 |
| 3.679e-07 | -14.82 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | MSigDB lists | PID_ECADHERIN_KERATINOCYTE_PATHWAY | 20 | 13 | 17758 | 2588 |
ZYX,PLCG1,FYN,VASP,RHOA,AKT1,CTNNB1,CDH1,FMN1,PIK3R1,PIK3CA,CTNND1,EGFR |
| 3.783e-07 | -14.79 | cell cycle process | biological process | GO:0022402 | 1057 | 216 | 16441 | 2455 |
SUN1,ACVR1,NDC80,XIAP,CUL1,PSME1,CNTROB,KIF2C,CCNB1,VASH1,SNX9,BARD1,CENPN,FANCI,TP73,CDKN2C,WEE1,PCNA,PSMD1,NUP210,CTNNB1,CNTRL,CEP78,PSMC2,DLG1,DNM2,TUBG1,KIF22,TUBA4A,PLK1,NEK4,CENPA,PBK,EZR,PRKAR2B,KIF13A,AURKB,CCNF,ANLN,SESN1,CDK1,RHEB,OPTN,PRIM1,PLK2,PPP2R4,CAB39,KLF11,PSMC1,RRAGD,PRKAA2,USH1C,CDKN1C,PPP1R12A,PRKAA1,PSMD7,KIF23,RACGAP1,NOTCH2,GPSM2,LMNA,CALR,RB1,SNX18,NEK2,MSH2,KNTC1,NUP85,PSMA5,CYP26B1,REC8,KIF20A,MYBL2,STRADB,KIF20B,ILK,PSMA4,RHOB,RASA1,MAPKAPK2,TSC1,PRKAG2,FAM64A,HTT,CGREF1,CDCA5,PAPD5,FAM83D,ARAP1,AURKA,NDE1,CCNB2,NUP58,DMPK,FBXW5,IRF1,RAD21,CCNE2,GAS2L1,SPC25,DLGAP5,CEP70,LFNG,TUBB4B,FOXM1,ACTR8,SLC2A8,PSME2,PTTG1,TP53,TDRKH,NUF2,BCL2L1,PRKACA,STIL,CDK14,IER3,CCND1,CCNA2,SETDB2,RALB,TACC2,KIF14,PLK4,CDKN1B,ZBTB49,CDKN2D,HSPA2,CKS2,PSRC1,SEPT6,CDC20,VPS4B,CDCA2,NUSAP1,PKMYT1,RAD17,CDC25C,PSMD3,TRIOBP,PPP1CB,OVOL1,XRCC3,CHMP4B,RGS14,SGOL1,MAD2L1BP,REEP4,PPP2R2D,CNEP1R1,ZC3HC1,MAPK12,PRKAR1A,NKX3-1,TAOK2,ARHGEF11,CKAP2,KLHL13,CIT,EPS8,ERCC6L,CDCA3,CDCA8,PSMD10,NES,TGFBR1,FBXO6,SPDL1,TIPRL,CKAP5,SAC3D1,TOP2A,E2F7,LLGL2,PTEN,CENPJ,TUBGCP6,PRC1,CKS1B,BUB1,IQGAP3,GFI1,SPRY2,CAMK2G,MSH6,SMC4,DUSP1,SUN2,ZWINT,RHOA,CENPC,WNT10B,PSMB4,PAPD7,ASPM,RGCC,DIAPH2,SKA1,KIF11,BORA,POLD3,DCTN6,ABCB1,E2F1,PKD2,SSNA1,CENPE,GEM,NUP37,CEP41,WDR62,NCAPG2,UBE2C,ESPL1,MELK,USP16 |
| 3.802e-07 | -14.78 | MAPK cascade | biological process | GO:0000165 | 372 | 92 | 16441 | 2455 |
SPRED1,RPS6KA1,PSME2,RET,CUL1,ERBB2,NRG2,IL18,MAPK4,RASGRP3,PSME1,PDGFB,SPTB,PDGFA,CALM2,RPS6KA2,PSMD1,SHC3,DOK4,PSMC2,IL31RA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,MAP3K3,RIPK2,PTGER4,DUSP4,MAP3K6,IRS2,FYN,JAK1,PSMD3,SH2D3C,KIAA1804,NOD2,MAP3K11,MAPK13,SPTBN5,NRG1,GAB1,PPP2R5D,PSMC1,MAPK12,TAOK2,TAB3,RASA2,CCM2,SOX9,PSMD7,PSMD10,CALM3,PKN1,TNFRSF19,FGF19,DUSP5,IRAK1,MAP3K9,MDFIC,MAPK11,ERBB3,IQGAP3,MAP3K7,NCAM1,MAPK7,SYK,PSMA5,CAMK2G,MDFI,RASGRF1,PSMB4,MAPKAPK3,RAPGEF2,CALM1,GRIN1,ELK1,FOS,PSMA4,MAPK8IP1,EGFR,RASA1,MAPKAPK2,SCG2,FGFR2,FGF18,GRIN2D,ITGAV,MAP3K5,JAK3,RPS6KA3 |
| 3.803e-07 | -14.78 | cell cycle | biological process | GO:0007049 | 1319 | 261 | 16441 | 2455 |
SUN1,ACVR1,KLK10,XIAP,CCNO,CUL1,PSME1,CNTROB,CCNB1,SEPT4,VASH1,SNX9,BARD1,CENPN,TP73,CDKN2C,WEE1,PSMD1,DNM2,TUBG1,PPP1CA,TUBA4A,NEK4,PBK,PRKAR2B,KIF13A,AURKB,CCNF,GINS4,PRIM1,PLK2,PPP2R4,PRDM5,HDAC1,MAPK13,ARF6,E2F8,LZTS1,ANXA11,CDKN1C,PRKAA1,KIF23,NOTCH2,GPSM2,LMNA,C9orf69,CALR,SNX18,NEK2,MSH2,MAPK7,NUP85,REC8,KIF20A,B9D2,MYBL2,KIF20B,ILK,PSMA4,RHOB,RASA1,PRKAG2,FAM64A,HTT,FAM83D,APPL2,ARAP1,AURKA,NDE1,NUP58,RPS6KA3,DMPK,IRF1,DLGAP5,CEP70,LFNG,TUBB4B,RPS6KA1,ACTR8,PTTG1,BLCAP,MAPK4,NUF2,BCL2L1,PRKACA,MNS1,CCND1,CCNA2,RALB,CDKN1B,DAB2IP,CDKN2D,PSRC1,SEPT6,VPS4B,CDCA2,NUSAP1,PKMYT1,RAD17,CCNB3,TRIOBP,PPP1CB,RGS14,MAPK12,PRKAR1A,TAOK2,NKX3-1,CKAP2,CENPI,EPS8,OSGIN2,CDCA3,NES,FBXO6,SPDL1,TIPRL,BEX2,CKAP5,E2F7,PTEN,CENPJ,TUBGCP6,PRC1,GFI1,SPRY2,MSH6,SMC4,ZWINT,PAPD7,TACC1,DIAPH2,PIM3,SKA1,KIF11,DCTN6,ABCB1,SSNA1,CENPE,GPER1,NUP37,WDR62,NCAPG2,ESPL1,MELK,USP16,CUL4B,NDC80,KIF2C,FANCI,NUP210,PCNA,CTNNB1,CNTRL,PSMC2,CEP78,DLG1,KIF22,PLK1,CENPA,ING1,EZR,ANLN,SESN1,CDK1,RHEB,OPTN,CAB39,KLF11,PSMC1,RRAGD,PRKAA2,USH1C,PPP1R12A,HJURP,PSMD7,RACGAP1,RB1,PIM1,KNTC1,PSMA5,CYP26B1,PARD3B,HMG20B,STRADB,MAPKAPK2,TSC1,UTP14C,CGREF1,PAPD5,CDCA5,CCNB2,RAD21,FBXW5,GAS2L1,CCNE2,AVPI1,SPC25,FOXM1,PSME2,SLC2A8,TP53,TDRKH,STIL,CDK14,IER3,SETDB2,TACC2,KIF14,PLK4,STEAP3,DIXDC1,ZBTB49,HSPA2,CKS2,CDC20,ERBB2IP,CDC25C,RBL1,PSMD3,OVOL1,CHMP4B,XRCC3,SGOL1,REEP4,MAD2L1BP,CNEP1R1,PPP2R2D,ZC3HC1,KLHL13,ARHGEF11,CIT,CDCA8,ERCC6L,PSMD10,TGFBR1,JAG2,SAC3D1,TOP2A,LLGL2,TRIM21,BRD7,CKS1B,BUB1,IQGAP3,CAMK2G,DUSP1,SUN2,RHOA,PSMB4,WNT10B,CENPC,ASPM,RGCC,BORA,POLD3,E2F1,PKD2,GEM,CEP41,UBE2C,AHR |
| 3.842e-07 | -14.77 | GNF2_MCM4 | MSigDB lists | GNF2_MCM4 | 53 | 23 | 17758 | 2588 |
HMMR,ZWINT,FOXM1,ASPM,CDC20,NDC80,CDCA8,RACGAP1,AURKB,KIF11,FANCI,TOP2A,PCNA,CCNA2,KIF14,AURKA,BUB1,CCNB2,UBE2C,ESPL1,MELK,SMC4,CKS2 |
| 3.847e-07 | -14.77 | WINZEN_DEGRADED_VIA_KHSRP | MSigDB lists | WINZEN_DEGRADED_VIA_KHSRP | 97 | 34 | 17758 | 2588 |
SERPINE2,CPEB4,ITGA6,SDC4,CCDC68,GDF15,F11R,DUSP5,BMP2,PDGFA,TGFBR3,CTGF,FRY,CYR61,ZFP36,TRPC1,NTN4,IFIT1,SPRY2,AMOTL2,CYP26B1,PDGFC,B3GNT2,PLAUR,PTGER4,TFAP2C,PTGS2,SLC4A4,NFKBIZ,SERPINI1,NR4A2,SPRY4,GEM,PKIA |
| 3.911e-07 | -14.75 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP | 188 | 54 | 17758 | 2588 |
NUDT6,LZTFL1,AK7,CTSB,ATP8A1,MCOLN3,POMGNT1,DHRS3,WWP2,RGS12,SESN3,RALGPS2,CDH1,KCNK5,SORL1,ALDH7A1,NTN4,DLG3,GFI1,F2R,PTPRE,IL10RB,MYRIP,FAM69A,CYP1B1,CYP26B1,SUSD3,ARAP2,ERMP1,MCTP1,MLEC,MMD,TACC1,MAPKAPK3,CORO2A,NPC2,DOCK5,FOS,TXK,ENDOD1,MAGED2,BANK1,FNTA,PPP2R5A,STK38,SIPA1L1,CSGALNACT1,ABCB1,SERPINB6,REEP4,ARSB,IFIH1,NRBP1,XDH |
| 4.007e-07 | -14.73 | positive regulation of phosphorylation | biological process | GO:0042327 | 1006 | 207 | 16441 | 2455 |
CCNC,TXN,ACVR1,TRIM5,CAMKK1,EPHA4,NRG2,PSME1,IL18,NENF,CCNB1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,PAK6,PSMD1,CTNNB1,CTGF,NPNT,SHC3,IL6ST,PSMC2,IL31RA,PIK3CA,DLG1,TNFRSF18,RASGRP1,PLK1,NEK4,SOD1,PRKAR2B,CDK1,VCP,PLCG1,GPRC5B,AREG,ANKRD6,TBX1,MADD,NOD2,MAP3K11,PRKCDBP,CAB39,F2RL1,PSMC1,GAB1,PRKAA2,PIFO,ITGA6,RASA2,SOX9,PRKAA1,PSMD7,CALM3,SORBS3,TEC,DUSP5,BMP2,IGF1R,CYR61,PAK2,MAP3K9,FNIP1,MDFIC,BRAT1,NPTN,MYDGF,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,MMD,MAPKAPK3,CALM1,KCTD20,PDE5A,STRADB,ILK,PSMA4,EGFR,RASA1,CDK5R1,FAS,MAPKAPK2,BCAR3,PRKAG2,INSR,SEMA4D,PELI2,PLPP3,CSF1,STK39,EFNA1,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,FLT3,EMP2,STIL,PDGFA,CCND1,ST5,RALB,KIF14,DAB2IP,RASGEF1A,F2R,HSPA2,DVL2,FRS3,MAP3K3,SIRT1,TIMP2,PSRC1,BAG4,RIPK2,AKT1,FZD4,PFKFB2,CD40,MAP3K6,FZD7,IRS2,FYN,JAK1,STK26,PSMD3,KIAA1804,SLC27A1,NRG1,SPTBN5,EFNA5,ARNT,PRKAR1A,PINK1,NKX3-1,TAOK2,TAB3,TRAF2,SDC4,FLOT1,PSMD10,TGFBR1,GDF15,PKN1,FGF19,ICAM1,PDCD10,ADORA1,IRAK1,PTEN,KNDC1,BMP7,BAX,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,PDGFC,RASGRF1,HES1,ADAM17,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,YES1,BCL10,BANK1,FGFR2,ACVRL1,FGF18,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,PKD2,GPER1,LRRK1,CENPE,FZD5,CD81 |
| 4.161e-07 | -14.69 | TYRKINASE | prints domains | PR00109 | 98 | 33 | 4759 | 661 |
TNK1,LMTK3,EPHA4,RET,ERBB2,TESK2,TEC,DDR1,MERTK,IGF1R,MAP3K9,ERBB3,EPHB4,MAP3K7,SYK,TESK1,EPHA1,YES1,ROR1,EGFR,TXK,EPHA10,FYN,INSR,JAK1,FGFR2,PTK7,AXL,LIMK1,MAP3K11,KIAA1804,RYK,JAK3 |
| 4.202e-07 | -14.68 | tissue morphogenesis | biological process | GO:0048729 | 564 | 128 | 16441 | 2455 |
ACVR1,LGR4,EPHA4,RET,GATA3,MPP5,PLXNA1,TGFBR3,CTNNB1,NPNT,ALDH1A3,DLG1,TACSTD2,PPP1CA,EZR,TFAP2C,LCP1,EDNRA,IRX3,AREG,TBX1,MYLK,TMTC3,SOX9,RAB23,NCKAP1,BMP2,VASP,CA2,ITGA3,IGF1R,CYR61,FLRT3,MEGF8,FRAS1,WNT3A,NTN1,SLC12A2,EPB41L5,SALL4,DCHS1,SCRIB,KIF20B,ILK,NPHP3,EGFR,TSC1,NCOA3,HTT,CSF1,SEMA3A,RARG,EGLN1,ADAMTS16,GRHL2,NF2,ST14,PKP2,STIL,DDR1,PRKACA,EXT2,ARTN,SETDB2,LMO4,SMO,TWIST1,DLG3,ETV4,DVL2,DAG1,SOCS3,ARHGAP35,SHROOM3,PTK7,NRG1,PLXND1,COBL,PRKAR1A,CTHRC1,NKX3-1,CCM2,SDC4,CTSZ,JAG2,HOXB2,FZD6,SIX4,GBX2,CTNNBIP1,PDCD10,BMP7,GPC3,FJX1,TFAP2A,BAX,ACTA2,MAP3K7,RPGR,SPRY2,GCNT1,TGIF1,HES1,RHOA,ADAM17,FMN1,PRICKLE1,FOXL1,BCL10,ARHGAP24,PROM1,FAT4,FGFR2,ACVRL1,TWSG1,TBX18,CTSV,SPINT2,NR4A3,SERPINB5,PKD2,HOXB13,FZD5,OSR1,PLOD3,SOX8,SHOX2,FOXA1 |
| 4.202e-07 | -14.68 | Pathways in cancer | KEGG pathways | hsa05200 | 397 | 99 | 6908 | 1076 |
CCNE2,CASP3,EPAS1,RALBP1,RET,TP53,XIAP,ERBB2,RASGRP3,BCL2L1,PDGFB,FLT3,PRKACA,APC2,GNB2,PDGFA,CCND1,DAPK2,CTNNB1,CDH1,RALB,PLCG2,MITF,SMO,PIK3CA,CDKN1B,ARNT2,PIK3CD,NFKB2,EGLN3,TFG,F2R,DVL2,RASGRP1,CKS2,AKT1,TCEB2,FZD4,CASP9,PTGER4,CBL,FZD7,EDNRA,PGF,PTGS2,PLCG1,JAK1,STAT1,HDAC1,TRAF5,ARNT,HSP90B1,NKX3-1,ARHGEF11,ITGA6,TRAF2,COL4A5,TGFBR1,GSTP1,ETS1,FGF19,ITGA2B,FZD6,MECOM,BMP2,RAC2,RB1,ITGA3,GNB5,IGF1R,PTEN,MSH2,DAPK1,BAX,CKS1B,WNT3A,PLCB2,MSH6,RHOA,WNT10B,PIK3R1,TCF7,FOS,GNA11,EGFR,RASGRP2,FAS,GNAS,CCDC6,FGFR2,FGF18,NFKBIA,E2F1,PIAS2,PLD1,ITGAV,FZD5,CTBP1,EGLN1 |
| 4.228e-07 | -14.68 | mitotic cell cycle | biological process | GO:0000278 | 802 | 171 | 16441 | 2455 |
ACVR1,NDC80,XIAP,CUL1,PSME1,CNTROB,KIF2C,CCNB1,SNX9,CENPN,FANCI,TP73,CDKN2C,WEE1,PCNA,PSMD1,NUP210,CNTRL,CEP78,PSMC2,DLG1,DNM2,TUBG1,KIF22,TUBA4A,PLK1,NEK4,CENPA,PBK,PRKAR2B,AURKB,CCNF,ANLN,CDK1,GINS4,OPTN,PRIM1,PLK2,PPP2R4,PRDM5,HDAC1,KLF11,E2F8,PSMC1,USH1C,PPP1R12A,PSMD7,KIF23,RACGAP1,GPSM2,LMNA,RB1,SNX18,NEK2,MSH2,KNTC1,NUP85,PSMA5,KIF20A,B9D2,MYBL2,KIF20B,PSMA4,RASA1,FAM64A,HTT,CDCA5,PAPD5,FAM83D,AURKA,NDE1,CCNB2,NUP58,DMPK,FBXW5,RAD21,CCNE2,DLGAP5,CEP70,SPC25,TUBB4B,FOXM1,ACTR8,PSME2,PTTG1,TP53,NUF2,BCL2L1,PRKACA,STIL,CDK14,IER3,CCND1,CCNA2,SETDB2,KIF14,PLK4,CDKN1B,CDKN2D,PSRC1,CDC20,VPS4B,CDCA2,NUSAP1,PKMYT1,RAD17,CDC25C,RBL1,PSMD3,TRIOBP,PPP1CB,CHMP4B,RGS14,SGOL1,REEP4,MAD2L1BP,PPP2R2D,CNEP1R1,ZC3HC1,CKAP2,KLHL13,CIT,CENPI,EPS8,ERCC6L,CDCA3,CDCA8,NES,PSMD10,SPDL1,CKAP5,SAC3D1,TOP2A,E2F7,PTEN,CENPJ,TUBGCP6,PRC1,CKS1B,BUB1,IQGAP3,GFI1,SPRY2,CAMK2G,SMC4,SUN2,ZWINT,RHOA,WNT10B,CENPC,PSMB4,PAPD7,ASPM,KIF11,BORA,POLD3,SKA1,DCTN6,ABCB1,E2F1,SSNA1,CENPE,GEM,NUP37,CEP41,WDR62,NCAPG2,UBE2C,ESPL1,MELK,USP16 |
| 4.354e-07 | -14.65 | axonogenesis | biological process | GO:0007409 | 674 | 148 | 16441 | 2455 |
MYL9,AGRN,EPHA4,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,RPS6KA2,PSMD1,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,MYH14,TIAM1,RASGRP1,ATL1,RNF165,EZR,ULK2,DPYSL3,PLCG1,MAP2,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,PSMD7,CALM3,DUSP5,RAC2,VASP,IGF1R,LRRN2,FLRT3,COL6A1,PAK2,CACNA1D,NCAM1,WNT3A,NTN1,PSMA5,DPYSL5,RGMB,CALM1,EPHA1,DPYSL4,RANBP9,NFIB,PSMA4,EGFR,RASA1,RHOB,CDK5R1,SEMA4D,MATN2,PITPNA,NR4A2,EFNA1,B4GAT1,ARPC2,JAK3,TRPC3,SEMA3A,RPS6KA3,KLF7,SPRED1,PSME2,RPS6KA1,ERBB2,RASGRP3,PDGFA,ARTN,DAB2IP,EPHB4,RASGEF1A,DLG3,ETV4,FRS3,SEMA3B,COL6A2,PRKCQ,ALCAM,MYL12A,DAG1,ARHGAP35,IRS2,EPHA10,FYN,JAK1,SLC9A6,PSMD3,SPTBN5,EFNA5,NRG1,PLXND1,COBL,COL9A3,ARHGEF11,ARHGEF7,FLOT1,PSMD10,COL4A5,PLPPR4,EFNB1,FGF19,ITGA2B,NRP2,NEO1,GBX2,RND1,KIF5B,ANK1,PTEN,BMP7,ERBB3,S100A6,CAMK2G,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,RAPGEF2,GRIN1,YES1,ABLIM2,MAP1B,CNTNAP1,FGFR2,FGF18,NR4A3,PGRMC1,RYK,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 4.375e-07 | -14.64 | PID_AURORA_B_PATHWAY | MSigDB lists | PID_AURORA_B_PATHWAY | 39 | 19 | 17758 | 2588 |
CENPA,RHOA,KIF20A,KLHL13,TACC1,NDC80,CDCA8,KIF23,RACGAP1,KIF2C,AURKB,RASA1,MYLK,AURKA,BUB1,SGOL1,CBX5,PPP2R5D,SMC4 |
| 4.427e-07 | -14.63 | organ morphogenesis | biological process | GO:0009887 | 876 | 184 | 16441 | 2455 |
EMX1,GAA,ACVR1,HSPG2,LGR4,GATA3,CUL1,PHOSPHO1,PLXNA1,FAM101B,SDC1,TGFBR3,CTGF,CTNNB1,STIM1,NPNT,IMPAD1,ALDH1A3,DLG1,TACSTD2,TIPARP,CPE,SP5,THRB,SPEF2,SOD1,ASXL1,EZR,TFAP2C,SAV1,PRKRA,ZFAND5,ABR,IRX3,AREG,TBX1,NKD1,MYLK,LRIG1,TDRD7,BMP1,HDAC1,HOXC13,CAPN1,FGD1,SCN5A,INPPL1,RUNX2,USH1C,TMTC3,ITGA6,SOX9,RAB23,NOTCH2,NCKAP1,DHRS3,ELF3,BMP2,CA2,IGF1R,CYR61,GATA2,FAM20C,MEGF8,FRAS1,BHLHE41,PRKCI,WNT3A,NTN1,ETV7,SLC12A2,MDFI,CYP26B1,DCHS1,FHL2,WHSC1,SCRIB,ILK,NPHP3,NFIB,EGFR,BCAR3,GNAS,NCOA3,INSR,HTT,COL13A1,CSF1,NAB2,EFNA1,GDF11,SHROOM2,SEMA3A,RARG,EGLN1,ADAMTS16,PAX6,NF2,HOXB7,GRHL2,LFNG,RPS6KA1,THRA,IRX4,ERBB2,P2RX7,COL18A1,PKP2,OSR2,STIL,PDGFA,SETDB2,SMO,CNNM4,TWIST1,EPHB4,ETV4,DVL2,DAG1,PTK7,STAT6,WWTR1,PNPLA6,TLE1,NRG1,PLXND1,CTHRC1,NKX3-1,LRP4,AES,CTSZ,TGFBR1,JAG2,HOXB2,SIX4,PPP2R3A,FZD6,GBX2,SGPL1,CTNNBIP1,PTEN,GPC3,BMP7,FJX1,TFAP2A,BAX,ACTA2,ADAM15,CITED2,GFI1,SPRY2,SYK,RPGR,MYO5A,GCNT1,HES1,PDGFC,WNT10B,FMN1,PPARA,BBS2,FOXL1,LEMD2,PITX2,PROM1,FAT4,DGCR2,TWSG1,FGFR2,FGF18,TBX18,NR4A3,CSGALNACT1,SERPINB5,PKD2,HOXB13,FHL1,SOX8,OSR1,FZD5,PLOD3,ZMIZ1,SHOX2,FOXA1 |
| 4.447e-07 | -14.63 | JOHNSTONE_PARVB_TARGETS_3_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_DN | 850 | 176 | 17758 | 2588 |
AASS,MRPS15,DNAJC3,CNOT8,SUDS3,NDC80,KIF2C,GALM,BARD1,MAP1LC3B,CENPN,CMTM6,FANCI,MAGOHB,CDKN2C,BTG3,PCNA,CTNNB1,AOX1,ANKRD12,SNX16,RP2,CTTN,TRAM1,MYBL1,TIPARP,ERAP2,LAMP2,NEK4,SMARCA2,CENPA,FOPNL,PBK,SNTB2,SERTAD4,C12orf65,PRKAR2B,PRKRA,CDK1,RHEB,SFXN1,ZNF367,E2F8,STARD3NL,RECQL,ALDH6A1,TMTC3,ETV5,KIF23,RACGAP1,SLC36A4,GPSM2,NCKAP1,PM20D2,PSIP1,SPIN4,FAM13B,RUNDC3B,NEK2,MSH2,USP1,USP38,SELK,STT3B,MPHOSPH9,EEF1D,RIMS2,HP1BP3,SNX7,MICB,OXR1,FBXO8,KIF20B,PDK3,G2E3,CYB5A,SLC6A6,SERTAD2,UAP1,OTUD6B,PRPS2,DCUN1D1,ATP1B3,PER3,C17orf75,CBX5,ELK4,CCNE2,ARHGAP11A,SLC25A24,SPC25,CEP70,NQO1,DLGAP5,BROX,RALBP1,PTTG1,TMX4,NUF2,MNS1,KTN1,UHRF1BP1L,PER2,APLP2,CCNA2,ACAP2,PLK4,SRR,RTKN2,RNASEH2A,PDIA6,NR2C1,UPF3A,EBAG9,TMEM200B,BAG4,RFK,FIGNL1,CDC20,GLO1,NUSAP1,ATP1B1,GTF2A2,H2AFV,SOCS3,ARHGAP35,RBL1,AXL,PPP1CB,CYP2U1,MRPS9,MZT1,GOLIM4,CKAP2,FRMD6,POC1B,CDCA8,FLOT1,NUCB2,SLC25A43,TIPRL,IRF2BPL,TOP2A,MDM1,PTEN,CTSC,PRC1,CKS1B,ALDH7A1,BUB1,HSPA13,IQGAP3,CNOT6L,MSH6,MYO5A,TMX1,SMC4,ZWINT,HMGN5,PLSCR1,PSMB4,ASPM,RAPGEF2,MRS2,NUB1,C2orf69,YES1,POLD3,KIF11,BCL10,TWSG1,CDCA7L,ERAP1,CENPE,NCAPG2,MELK |
| 4.479e-07 | -14.62 | EZR (ezrin) | protein interactions | 7430 | 144 | 47 | 16036 | 2547 |
ENO2,NF2,GNPDA1,IQGAP1,PTTG1,DGKQ,HEXB,SELL,ISYNA1,FBXO6,OAT,SLC9A3R2,ICAM1,PLS3,CALR,RCN1,PDCD10,CTNNB1,CDH1,P4HB,DLG1,AKR1B1,WWP1,TAGLN2,SYK,SCYL3,GPX4,VPS11,RHOA,PIK3R1,EIF5A2,EZR,PYGL,PLS1,ARHGDIB,PRX,LCP1,EGFR,FAS,HLA-B,TSC1,PHLPP2,AURKA,PDXK,TMEM8B,ARF6,L1CAM |
| 4.489e-07 | -14.62 | Fc epsilon receptor (FCERI) signaling | REACTOME pathways | R-HSA-2454202 | 342 | 86 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,CUL1,RASGRP3,PSME1,ITPR2,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PLCG2,PSMC2,PIK3CA,CDKN1B,DUSP10,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,PRKCQ,AGO4,DUSP4,ITPR3,IRS2,PLCG1,FYN,JAK1,PPP2R5A,PSMD3,MAP3K11,NRG1,SPTBN5,PPP2R5D,PSMC1,GAB1,TNRC6C,TAB3,RASA2,PSMD7,CALM3,PSMD10,TEC,PHLPP1,FGF19,DUSP5,ITGA2B,PTEN,PAK2,ERBB3,MAP3K7,NCAM1,SYK,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,FOS,PSMA4,EGFR,RASA1,BCL10,RASGRP2,TXK,FGFR2,PHLPP2,NFKBIA,FGF18,ITPR1,UBE2D2,ARRB1,GRIN2D,JAK3 |
| 4.523e-07 | -14.61 | PROTEIN_KINASE_ACTIVITY | MSigDB lists | PROTEIN_KINASE_ACTIVITY | 283 | 73 | 17758 | 2588 |
ACVR1,RPS6KA1,TESK2,ERBB2,PDGFRL,MAPK4,DDR1,FLT3,DAPK2,RPS6KA2,PLK4,PHKA2,PLK1,MAP3K3,NEK4,MARK1,RIPK2,AKT1,ACVR1C,PBK,ROR1,XRCC6BP1,MAP3K6,STK17B,CDK1,PTK7,LIMK1,STK38,AXL,MYLK,MAP3K11,MAPK13,MAPK12,PINK1,TAOK2,CIT,TGFBR1,TRIB2,MERTK,NRP2,IGF1R,IRAK1,PAK2,MAP3K9,PRKCI,NEK2,SGK3,SGK1,MAPK11,PIM1,ERBB3,MAP3K7,MAPK7,PHKG2,TESK1,MAPKAPK3,STRADB,EIF2AK1,PDK3,ILK,CDK5R1,EGFR,TXK,STK17A,MAPKAPK2,INSR,ACVRL1,RYK,NR4A3,MAP3K5,HIPK3,RPS6KA3,DMPK |
| 4.529e-07 | -14.61 | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN | 184 | 53 | 17758 | 2588 |
PARP12,IL15,SOD2,C5orf30,RAB23,GMPR,UBE2Z,HERC5,PDGFRL,CD274,HERC6,DNAH3,PRRG4,TMCC3,EPDR1,INPP5E,SP100,TRANK1,ITGB8,DRAM1,TWIST1,TSPAN13,IFIT1,OAS3,APOBEC3G,CKAP4,MX1,ARAP2,MICB,USP18,NUB1,C3orf52,RUNX3,GGH,EAF2,IFIT3,CYB5A,PI4K2B,UEVLD,C19orf66,TRIM69,C1orf21,NLRC5,NR4A3,AGFG2,IRF7,NFKBIZ,CMPK2,SLC31A2,IFIH1,CPEB2,MELK,WDR63 |
| 4.529e-07 | -14.61 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_UP | 184 | 53 | 17758 | 2588 |
COL9A3,TXN,IL15RA,ENO2,IL15,PSME2,TSC22D3,TAP1,SOD2,COL4A5,DUSP5,CHST2,NRP2,B4GALNT1,TOP2A,BTG3,ZNF75D,CYR61,GYS1,FAM102A,DIXDC1,TAGLN2,CNGA1,NFKB2,GFI1,SGCB,SLC12A2,TIAM1,FAM69A,DUSP1,LAMP3,POU6F1,IFITM3,STAT4,RAPGEF2,SAT1,AK4,EIF2AK1,DUSP4,IFIT3,CYB5A,CD83,SOCS3,TRIM9,BTG1,PLK2,NFKBIA,FGF18,E2F1,NR4A3,LTBP2,TRAF5,KLF7 |
| 4.539e-07 | -14.61 | breast-carcinoma-basal_(triple-negative)_carcinoma | COSMIC cancer mutations | breast-carcinoma-basal_(triple-negative)_carcinoma | 3077 | 537 | 17775 | 2585 |
ACACB,TRIM24,GRIK2,SLC25A13,RET,XIAP,NRG2,TRAPPC8,BAIAP3,MORF4L2,CARD10,LTBP3,GRM5,WEE1,DNAH6,PPP1CA,TINAGL1,PIK3CD,TIAM1,TIPARP,TNIP1,PRKAR2B,PPP1R14C,GINS4,COL12A1,LCP1,SLC44A3,PIAS3,PLCG1,TRIM47,MPRIP,ATP7B,MAP3K11,HDAC1,RNASEL,HSPB1,GAB1,E2F8,HOXC13,SCN5A,NFKBIE,ITGA6,SOX9,RAB23,MERTK,RAVER2,ELF3,RAC2,CD22,NEK2,USP1,USP38,MAPK7,ULBP2,C9orf72,PAQR7,STAT4,SHARPIN,CALCRL,ELK1,RHOB,STK17A,PTPRF,IL1R1,CACHD1,SLC4A4,ETS2,HTT,ITPR1,AURKA,NDE1,TRPC3,RPS6KA3,WDR63,TPRN,LFNG,GALNT12,PRKACA,KTN1,REPS1,RCN1,CCND1,MUC16,ST5,CDH1,ACSL4,ZNF365,ETV4,SCN3A,FZD4,SEPT6,SYNE2,TANC1,IRS2,SHROOM3,TTC12,AXL,WWTR1,PLEKHG1,GEN1,ARNT,MAPK12,TAOK2,TNRC6C,MPZL1,PARP14,CKAP2,TRAF2,OSGIN2,PKN1,ETS1,NEO1,PDIA4,CAPN2,DTX3L,DIRAS3,PDCD10,IRAK1,GPC3,BAX,WWP1,IGFBP2,MAPK11,RAG1,PARP9,BCL9,RAPGEF2,PIK3R1,UBE2A,CNTNAP1,BTG1,CCDC6,PPM1H,ARFGAP3,ITGAV,OSR1,FOXA1,TLL2,PPM1J,EPHA4,NDRG2,TEX2,MGAT5B,PDGFB,SDC1,SPTB,RPS6KA2,NUP210,CTNNB1,CNTRL,MKRN3,LMAN2L,SLC44A1,MITF,DUSP10,TLN2,MYBL1,CCDC38,ZNF462,PLK1,CELSR2,STAU2,CR2,NKAIN1,ESYT1,ANLN,TRUB1,RHEB,DPYSL3,TNS4,P4HA2,HOXA9,PIK3C2B,PRKAA2,PARP12,RUNX2,HJURP,RASA2,PSMD7,CNTNAP2,DOCK11,PGAP1,BMP2,TNS3,RB1,IGF1R,PIM1,DPYSL5,PLEKHA6,USP31,SPATA13,KBTBD8,G2E3,RASGRP2,MAPKAPK2,PVRL2,OTUD6B,PLD1,FAM45A,USP43,KCNAB3,NF2,FOXM1,TP53,CCDC68,ERBB2,RASGRP3,CCNL1,STIL,PER2,CDK14,PDGFA,ATP6V0B,EFR3A,TACC2,N4BP3,PLCG2,ZDHHC23,BCL6,CDH3,GYS1,ESPN,NOTCH3,SCN2A,DVL2,AKT1,ACO1,PTGER4,DNAJC10,PTPRJ,PTK7,STK38,KLHL13,RUSC2,NKRF,JAG2,VPS26A,PPP2R3A,FZD6,CD109,FOXP2,UBE2J1,SGK1,BUB1,SYK,DUSP1,P2RX4,HES1,RHOA,NR3C1,AMFR,PRICKLE1,MAML2,TRIM35,COL7A1,BCAR1,MAPK8IP1,BCL10,USP6,FAT4,NEIL3,FGF18,ACADM,TBC1D4,GOLGB1,DIS3L,FAM171B,ACVR1,HSPG2,SSH1,PPFIBP2,C1orf198,PAK6,CYP1A1,ELMO2,OSBPL3,FOSB,PIK3CA,AOX1,ATRNL1,HYLS1,TFG,SMYD5,ORAI2,SPATA18,ACVR1C,CASP9,TNS1,AURKB,CCNF,SAV1,RBM47,AREG,PPP2R4,MAPK13,SPRY4,TRAF5,SEMA6B,INPPL1,MRPL44,PRKAA1,NOTCH2,PSIP1,MECOM,ZNRF2,AIM1,PRKG1,DAPK1,RUNDC3B,MSH2,SORL1,KCTD3,EEF1D,SOCS5,EPB41L5,KCNJ12,GCC2,DDB2,ZNF84,MFI2,CEP89,AMER1,WHSC1,FBXO10,RASA1,PDE11A,FAS,PRKAG2,AGBL5,MPP2,PIAS2,SAMD8,CDK18,PER3,MAP3K5,ELK4,PLA2G4A,KIF3C,SPRED1,TCF25,TRIP10,RALBP1,SUZ12,IQGAP1,DDIT4L,ATP2C2,RNF182,BCL2L1,DDR1,FLT3,MNS1,SLC25A35,CD46,CCNA2,RALB,CDKN1B,DAB2IP,RNASEH2A,EPHB4,FLOT2,MYO5B,UTRN,CLSTN1,PRKCQ,PKMYT1,ITPR3,CBL,C15orf39,FZD7,EPHA10,FYN,PPP2R5A,JAK1,STAT1,PPP1CB,NRG1,PRKAR1A,OTUD5,IGFBP6,CENPI,EPS8,HERC5,DNAH3,FGF19,SIX4,LGALS3BP,WWP2,TMCC3,SNTA1,PHF7,PTEN,SGK3,ATP8B1,ERBB3,ERCC2,MAP3K7,SPRY2,MSH6,NCOA2,PDGFC,RASGRF1,FURIN,PARP4,FOS,GPLD1,DGCR2,RCBTB2,FGFR2,RIN3,GRIN2D,FZD5,USP16,JARID2,CASP3,LTBP1,DNER,KREMEN1,SH3KBP1,MAGOHB,LRRC6,RASGRP1,LAMP3,CYP1B1,ITCH,ACBD3,USP18,RGAG1,ARHGDIB,ROR1,ADRBK2,EDNRA,LRRC42,MAN2A2,NEIL1,GPRC5B,MADD,TRIM45,PPP2R5D,LASP1,ETV5,CALM3,SAMD9,ADAMTSL4,DUSP5,LYSMD4,OTUD1,PRKCI,NPTN,KNTC1,ZRANB1,SNED1,CCDC88A,ELK3,OXR1,PDE5A,VWA1,KIAA1109,STEAP1,C3orf58,EGFR,GNAS,TSC1,INSR,UAP1,NFKBIA,RHOBTB2,EGFL7,YOD1,SHROOM2,JAK3,RARG,TOB1,LMO7,PAX6,MRAS,TDRKH,PHLDA1,EXT2,KCTD9,SS18,SETDB2,CYP4F11,SMO,TWIST1,RPN2,NFKB2,MAP3K3,TAF5,KREMEN2,PTPRU,DUSP4,CD40,FANCE,CDC25C,CASP4,MAP3K6,SOCS3,ALDH5A1,STAT6,CYP2U1,PLXND1,AKNA,MAD2L1BP,LIFR,ABCA1,SORT1,TSPAN15,ARHGEF11,FRMD6,LRP4,COL4A5,TGFBR1,INTS8,ITGA2B,MZT2A,TAF1B,MYCL,BRD7,MYO5A,PGM1,ADAM17,WNT10B,ASPM,RC3H2,FAM73B,MAP1B,ARHGAP24,CASP7,RND3,C2orf70,RAP2C,DTX4,ARRB1,OTUB2,GEM,LRRC57,ABCG1 |
| 4.539e-07 | -14.61 | basal_(triple-negative)_carcinoma | COSMIC cancer mutations | basal_(triple-negative)_carcinoma | 3077 | 537 | 17775 | 2585 |
ACACB,TRIM24,GRIK2,SLC25A13,RET,XIAP,NRG2,TRAPPC8,BAIAP3,MORF4L2,CARD10,LTBP3,GRM5,WEE1,DNAH6,PPP1CA,TINAGL1,PIK3CD,TIAM1,TIPARP,TNIP1,PRKAR2B,PPP1R14C,GINS4,COL12A1,LCP1,SLC44A3,PIAS3,PLCG1,TRIM47,MPRIP,ATP7B,MAP3K11,HDAC1,RNASEL,HSPB1,GAB1,E2F8,HOXC13,SCN5A,NFKBIE,ITGA6,SOX9,RAB23,MERTK,RAVER2,ELF3,RAC2,CD22,NEK2,USP1,USP38,MAPK7,ULBP2,C9orf72,PAQR7,STAT4,SHARPIN,CALCRL,ELK1,RHOB,STK17A,PTPRF,IL1R1,CACHD1,SLC4A4,ETS2,HTT,ITPR1,AURKA,NDE1,TRPC3,RPS6KA3,WDR63,TPRN,LFNG,GALNT12,PRKACA,KTN1,REPS1,RCN1,CCND1,MUC16,ST5,CDH1,ACSL4,ZNF365,ETV4,SCN3A,FZD4,SEPT6,SYNE2,TANC1,IRS2,SHROOM3,TTC12,AXL,WWTR1,PLEKHG1,GEN1,ARNT,MAPK12,TAOK2,TNRC6C,MPZL1,PARP14,CKAP2,TRAF2,OSGIN2,PKN1,ETS1,NEO1,PDIA4,CAPN2,DTX3L,DIRAS3,PDCD10,IRAK1,GPC3,BAX,WWP1,IGFBP2,MAPK11,RAG1,PARP9,BCL9,RAPGEF2,PIK3R1,UBE2A,CNTNAP1,BTG1,CCDC6,PPM1H,ARFGAP3,ITGAV,OSR1,FOXA1,TLL2,PPM1J,EPHA4,NDRG2,TEX2,MGAT5B,PDGFB,SDC1,SPTB,RPS6KA2,NUP210,CTNNB1,CNTRL,MKRN3,LMAN2L,SLC44A1,MITF,DUSP10,TLN2,MYBL1,CCDC38,ZNF462,PLK1,CELSR2,STAU2,CR2,NKAIN1,ESYT1,ANLN,TRUB1,RHEB,DPYSL3,TNS4,P4HA2,HOXA9,PIK3C2B,PRKAA2,PARP12,RUNX2,HJURP,RASA2,PSMD7,CNTNAP2,DOCK11,PGAP1,BMP2,TNS3,RB1,IGF1R,PIM1,DPYSL5,PLEKHA6,USP31,SPATA13,KBTBD8,G2E3,RASGRP2,MAPKAPK2,PVRL2,OTUD6B,PLD1,FAM45A,USP43,KCNAB3,NF2,FOXM1,TP53,CCDC68,ERBB2,RASGRP3,CCNL1,STIL,PER2,CDK14,PDGFA,ATP6V0B,EFR3A,TACC2,N4BP3,PLCG2,ZDHHC23,BCL6,CDH3,GYS1,ESPN,NOTCH3,SCN2A,DVL2,AKT1,ACO1,PTGER4,DNAJC10,PTPRJ,PTK7,STK38,KLHL13,RUSC2,NKRF,JAG2,VPS26A,PPP2R3A,FZD6,CD109,FOXP2,UBE2J1,SGK1,BUB1,SYK,DUSP1,P2RX4,HES1,RHOA,NR3C1,AMFR,PRICKLE1,MAML2,TRIM35,COL7A1,BCAR1,MAPK8IP1,BCL10,USP6,FAT4,NEIL3,FGF18,ACADM,TBC1D4,GOLGB1,DIS3L,FAM171B,ACVR1,HSPG2,SSH1,PPFIBP2,C1orf198,PAK6,CYP1A1,ELMO2,OSBPL3,FOSB,PIK3CA,AOX1,ATRNL1,HYLS1,TFG,SMYD5,ORAI2,SPATA18,ACVR1C,CASP9,TNS1,AURKB,CCNF,SAV1,RBM47,AREG,PPP2R4,MAPK13,SPRY4,TRAF5,SEMA6B,INPPL1,MRPL44,PRKAA1,NOTCH2,PSIP1,MECOM,ZNRF2,AIM1,PRKG1,DAPK1,RUNDC3B,MSH2,SORL1,KCTD3,EEF1D,SOCS5,EPB41L5,KCNJ12,GCC2,DDB2,ZNF84,MFI2,CEP89,AMER1,WHSC1,FBXO10,RASA1,PDE11A,FAS,PRKAG2,AGBL5,MPP2,PIAS2,SAMD8,CDK18,PER3,MAP3K5,ELK4,PLA2G4A,KIF3C,SPRED1,TCF25,TRIP10,RALBP1,SUZ12,IQGAP1,DDIT4L,ATP2C2,RNF182,BCL2L1,DDR1,FLT3,MNS1,SLC25A35,CD46,CCNA2,RALB,CDKN1B,DAB2IP,RNASEH2A,EPHB4,FLOT2,MYO5B,UTRN,CLSTN1,PRKCQ,PKMYT1,ITPR3,CBL,C15orf39,FZD7,EPHA10,FYN,PPP2R5A,JAK1,STAT1,PPP1CB,NRG1,PRKAR1A,OTUD5,IGFBP6,CENPI,EPS8,HERC5,DNAH3,FGF19,SIX4,LGALS3BP,WWP2,TMCC3,SNTA1,PHF7,PTEN,SGK3,ATP8B1,ERBB3,ERCC2,MAP3K7,SPRY2,MSH6,NCOA2,PDGFC,RASGRF1,FURIN,PARP4,FOS,GPLD1,DGCR2,RCBTB2,FGFR2,RIN3,GRIN2D,FZD5,USP16,JARID2,CASP3,LTBP1,DNER,KREMEN1,SH3KBP1,MAGOHB,LRRC6,RASGRP1,LAMP3,CYP1B1,ITCH,ACBD3,USP18,RGAG1,ARHGDIB,ROR1,ADRBK2,EDNRA,LRRC42,MAN2A2,NEIL1,GPRC5B,MADD,TRIM45,PPP2R5D,LASP1,ETV5,CALM3,SAMD9,ADAMTSL4,DUSP5,LYSMD4,OTUD1,PRKCI,NPTN,KNTC1,ZRANB1,SNED1,CCDC88A,ELK3,OXR1,PDE5A,VWA1,KIAA1109,STEAP1,C3orf58,EGFR,GNAS,TSC1,INSR,UAP1,NFKBIA,RHOBTB2,EGFL7,YOD1,SHROOM2,JAK3,RARG,TOB1,LMO7,PAX6,MRAS,TDRKH,PHLDA1,EXT2,KCTD9,SS18,SETDB2,CYP4F11,SMO,TWIST1,RPN2,NFKB2,MAP3K3,TAF5,KREMEN2,PTPRU,DUSP4,CD40,FANCE,CDC25C,CASP4,MAP3K6,SOCS3,ALDH5A1,STAT6,CYP2U1,PLXND1,AKNA,MAD2L1BP,LIFR,ABCA1,SORT1,TSPAN15,ARHGEF11,FRMD6,LRP4,COL4A5,TGFBR1,INTS8,ITGA2B,MZT2A,TAF1B,MYCL,BRD7,MYO5A,PGM1,ADAM17,WNT10B,ASPM,RC3H2,FAM73B,MAP1B,ARHGAP24,CASP7,RND3,C2orf70,RAP2C,DTX4,ARRB1,OTUB2,GEM,LRRC57,ABCG1 |
| 4.559e-07 | -14.60 | response to stimulus | biological process | GO:0050896 | 7571 | 1243 | 16441 | 2455 |
GRIK2,AK7,SLC25A13,RET,CCNO,BAIAP3,DPP8,SPSB1,CMTM6,CARD10,GRM5,PHYHIP,UBE2T,DNM2,CLDN4,CRY2,PPP1CA,TIAM1,IL10RB,TIPARP,CPE,NEK4,CDA,KDELR3,PRKAR2B,RNF19B,ARF4,GINS4,LCP1,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,ATP7B,NOD2,HDAC1,RNASEL,ITPKA,HSPB1,STARD13,ANXA11,SCN5A,SEC61G,ITGA6,MTL5,RAB23,GPSM2,HPCAL4,ATG4A,MARCH8,TFAP4,RAC2,ZCCHC17,MEGF8,RIMS3,FLRT3,RANBP1,MAP3K9,USP1,ALPK1,MYDGF,CNGA1,PANX2,MAPK7,DGKG,ULBP2,NUP85,PAQR7,REC8,MAPKAPK3,ERO1A,SHARPIN,FHL2,ELK1,NPHP3,DPYSL4,PSMA4,GNA11,IL1R1,FNTA,RAET1L,DGAT2,STK39,GDF11,CBX5,NUP58,TMEM173,DOCK9,DMPK,NQO1,LFNG,INPP5D,CD82,PTTG1,MAPK4,GRK6,MGST2,CDH1,SH3BP1,TAX1BP3,LRP11,DLG3,RASGEF1A,ETV4,MX1,SEC61B,COL6A2,RIPK2,APOBEC3D,PFKFB2,VPS4B,SYP,XRCC6BP1,TANC1,GIGYF1,ALDH3B1,CDK19,SHROOM3,CORO1C,WFS1,AXL,MAPK12,CTHRC1,HSP90B1,MPZL1,TRAF2,CCM2,SDC4,HABP4,FLOT1,BTN3A1,PLPPR4,ZNF219,IFT27,NFAT5,SGPL1,CTNNBIP1,DIRAS3,PDCD10,ITGB8,KNDC1,GPC3,CST3,BAX,IGFBP2,RAG1,PARP9,OPLAH,PLSCR1,PIK3R1,NUB1,UBE2A,AK4,CNTNAP1,HCP5,PLOD2,RAB11FIP2,SYT7,SLC35B3,DBI,NR4A3,OSER1,SSNA1,ITGAV,CMPK2,OSR1,CD81,WDR45B,PHC1,BCAM,TNK1,EPAS1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,SPTB,FANCI,SUSD2,CPNE2,RPS6KA2,NUP210,CTNNB1,NPNT,P4HB,IL6ST,ARL1,PSMC2,PAPSS1,MITF,ABCA2,NTN4,SCARA3,PLK1,THRB,KCNIP3,MARK1,CELSR2,NFE2L1,CR2,ARFRP1,SESN1,KDM4D,KCNMB4,KPNA2,MYL12B,RRAGD,RUNX2,LGALS3,DNAJB2,RASA2,PDCL,PSMD7,RAB6A,NCKAP1,FBLN1,ANO1,TIMP1,KIF13B,SLC30A6,SELK,AHCY,PIM1,NTN1,WNT3A,DPYSL5,RGMB,STRADB,SCRIB,PDK3,NMT2,CDK5R1,RASGRP2,PHLPP2,NLRC5,PLD1,SEMA3A,USP43,RAD21,TMX4,TP53,P2RX7,RHPN2,STIL,EMP2,BCAP31,IER3,TTC21B,PDGFA,BCL6,CDH3,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,TAPBP,PTPRJ,IDE,ABHD12,RBL1,STK38,MAOA,XRCC3,EFNA5,IRF7,ARHGAP4,ZMAT1,PINK1,CPEB4,TAB3,CTSB,GNAL,MCTP2,CDCA8,ERCC6L,GDF15,AIP,IL22RA1,DNAJB9,FZD6,NRP2,M6PR,UBE2J1,TFAP2A,SGK1,IL17RA,TRIM21,HMGCL,TSPAN13,SYK,ATP2B1,GCNT1,DUSP1,P2RX4,HES1,RHOA,PLAUR,MAML2,GGH,BBS2,TXNDC11,DGKE,BCL10,DDAH1,SCG2,NEIL3,FGF18,E2F1,ICOSLG,PTGES,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,TSC22D3,CUL1,PSME1,PDGFRL,CAMK1D,VASH1,PJA2,PICK1,PAK6,TYMP,CYP1A1,STIM1,FOSB,POLL,PIK3CA,IRF2,TACSTD2,METAP2,SPATA18,ACVR1C,BNIP3L,SLC35C1,POR,RAB2B,SH2D3C,MAPK13,NFKBIZ,F2RL1,FGD1,SEMA6B,RECQL,THEMIS2,PRKAA1,AKAP17A,TNFRSF19,TSPAN7,PSIP1,MESDC2,CALR,RALGPS2,RPL39,VASN,PPP4R1,MSH2,TPST1,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,GPR161,SOCS5,GFPT1,PRODH,CALM1,DCHS1,WHSC1,NPC2,EPHA1,ANTXR1,NFIB,PDE11A,MMP15,PELI2,MATN2,PIAS2,MPP2,ARAP1,APPL2,CABIN1,IFIH1,EHD1,SPRED1,KIF3C,TCTN2,REPS2,THRA,RALBP1,NDRG1,FTH1,BCL2L1,FLT3,DDR1,CYP39A1,ZFYVE9,EPS8L2,APOBEC3B,CD46,NOV,CCNA2,ACAP2,RALB,RNASEH2A,PDE4D,EPHB4,OSBPL7,TSPAN1,SULT2B1,MED30,SEMA3B,ATG4D,DOCK4,ATP1B1,RAD17,PYGO1,CBL,ASB13,ITPR3,ALCAM,FZD7,DDOST,NGFRAP1,TSPAN18,CBX7,PRKAR1A,PLSCR4,IGFBP6,DEPDC1,CENPI,EPS8,HERC5,PLD2,FBXO6,SPDL1,EFNB1,FGF19,ADGRB2,HLA-A,CKAP5,RASSF8,E2F7,GNB5,FUT8,CD9,ERBB3,CITED2,TTPA,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,B3GNT2,PAPD7,FBXO9,DIAPH2,YES1,FOS,KIF11,TIMP3,FGFR2,RIN3,ABCB1,RYK,ERAP1,RABL6,LRRK1,FZD5,MELK,RGMA,CCNC,UGT8,FAF2,MAP1LC3B,SLC8B1,TRIM68,HTR1D,ZFYVE16,EPCAM,RAB15,SIVA1,TRPC1,ASH2L,CTTN,IL1RAP,SP5,LAMP3,CYP1B1,NLRP4,CXXC5,CENPA,ASXL1,ITCH,USP18,ARHGDIB,GPRC5B,HPSE,MADD,CAB39,NRGN,NR2C2,PCSK5,ARAP3,SERPINE2,PPP1R12A,ETV5,ASB9,ABCG2,CALM3,TEC,DUSP5,SPP1,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,SRP54,BRAT1,NPTN,HLA-C,C10orf54,ZRANB1,SLC12A2,CCDC88A,MDFI,ELK3,VWA1,PDE5A,RANBP9,RHPN1,INSR,TMEM30A,SH3BP4,RAB31,NXPH4,SHROOM2,JAK3,TOB1,APOL2,COL16A1,RARG,DRD1,DYNLRB1,SORBS1,PAX6,SOD2,PDIA5,COL18A1,IL27RA,MRAS,EXT2,ARTN,CYP4F11,KIF14,DIXDC1,EPB41L4B,NFKB2,CHP1,PTPRU,MRPS35,CD40,CDC25C,FANCE,CASP4,ARHGAP35,SOCS3,JADE1,STAT6,SECTM1,TLE1,SPTBN5,RCAN2,ABCA1,GCLM,ARHGEF11,SHPRH,CIT,ARHGEF7,SERPINB9,TGFBR1,COL4A5,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,KIF5B,TOP2A,ADRBK1,BMP7,TOX2,ZDHHC13,ACTA2,RPGR,MYO5A,PGM1,WNT10B,RC3H2,RGCC,RUNX3,NDRG3,LEPR,CTSL,ARHGAP24,CD8A,CASP7,SWAP70,RND3,CTSV,RAP2C,DTX4,ARRB1,UACA,PLOD3,AHR,CD33,ABCG1,NGEF,TRIM24,IL15RA,ADD1,TRIM5,DNAJC3,SMARCAL1,FBXO2,XIAP,NRG2,IL18,MORF4L2,KIF26A,BARD1,CA8,PHF1,TP73,DAPK2,CALM2,WEE1,ZYX,TGFBR3,RGS12,PSMD1,ARHGAP42,CYP2S1,ALDH1A3,KLF3,SLC46A1,MANF,PIK3CD,TINAGL1,SEMA3G,APOBEC3G,ERAP2,TUBA4A,TNIP1,SPRTN,LOXL2,F12,MYOM1,CYP4F3,PGF,DNM1L,LIMK1,MYLK,MAP3K11,SERPINB6,ARF6,GAB1,NUAK1,CYP2J2,SOX9,ZNRF3,MERTK,LMNA,ELF3,FAM13B,STT3B,NCAM1,NDUFA12,EPHX1,UFD1L,SALL4,STAT4,CALCRL,SRSF5,ILK,MEST,RHOB,CYB5A,STK17A,PTPRF,NCOA3,SEMA4D,HTT,ITPR1,OSMR,DYSF,AURKA,MDH1,ALG2,B4GAT1,ARPC2,NDE1,TRPC3,RPS6KA3,EGLN1,ARHGAP11A,PAPSS2,TUBB4B,ACTR8,WDTC1,IL13RA1,NUF2,PRKACA,APC2,KTN1,TNFSF9,ZNF385B,CDS1,CCND1,SCNN1A,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,RNF169,ENPP4,LGALS8,FZD4,NRBF2,RAB38,IRS2,SLC9A6,WWTR1,SIPA1L1,INPP4B,TRABD2A,RGS14,GEN1,ARNT,TNRC6C,NKX3-1,TAOK2,RASSF7,PDIA3,PKN1,GSTP1,ETS1,TIPRL,ICAM1,NEO1,PDIA4,CAPN2,DTX3L,CXCL16,ANK1,ADD3,IRAK1,CTSC,MCF2L,FDXR,TMBIM6,ADAM15,WWP1,MAPK11,AK3,S100A6,TMX1,HCN3,AMOTL2,CTNNAL1,BCL9,RAPGEF2,GRIN1,NEURL1B,SKA1,ABLIM2,TXK,PITX2,BTG1,KIAA0141,ACVRL1,NR1D2,HMGA1,CENPE,NUP37,USF2,CYBRD1,FOXA1,MYL9,SIGIRR,UNC93B1,AGRN,CUL4B,EPHA4,NDC80,TP53I11,HDAC6,PDGFB,SDC1,PCNA,SHC3,DUSP10,TNFRSF18,S100A13,CD55,MCTP1,CITED4,EZR,ERP44,KLK6,PRKRA,IDH1,CDK1,VCP,PLEKHB1,RHEB,OPTN,DPYSL3,PLCH1,WIPI1,MAP2,CTNND1,PIK3C2B,PIEZO1,MAFF,PRKAA2,BMF,HLA-F,RACGAP1,CNTNAP2,DOCK11,DHRS3,IL18R1,CORO1B,BMP2,RB1,VASP,IGF1R,GATA2,PAK2,MDFIC,PLCB2,PSMA5,ABCC1,CYP26B1,CORO2A,TCF7,EIF2AK1,IFIT3,MAPKAPK2,PVRL2,CSF1,ITGA7,LTBP2,ATP1B3,IFI6,RNF146,NF2,UGP2,FOXM1,XYLT1,DGKA,ERBB2,CCDC68,RASGRP3,SLC7A2,CYP26A1,SDF4,PER2,CDK14,RAD23A,ATP6V0B,SRPX,PLCG2,SRR,EGLN3,SCN2A,DVL2,CTH,SIRT1,TIMP2,MBP,TCEB2,FIGNL1,CDC20,MYL12A,DNAJC10,DUOX1,RTN4RL1,ATP1A1,PTK7,PSMD3,LTA4H,CMTM4,GSDMD,COL9A3,CD63,ADGRG1,DAP,SWI5,PSMD10,SELL,GABRG2,JAG2,CRABP2,SIRPA,PPP2R3A,GBX2,BUB1,KLF9,CAMK2G,PSMB4,NR3C1,IFITM3,AMFR,LITAF,PPARA,TRIM35,FXR2,PELI3,AKAP3,BCAR1,MAPK8IP1,PRDX4,CD83,SERPINA1,FAT4,TWSG1,NAT1,NMI,PGRMC1,PKD2,NDFIP1,TBC1D4,ACVR1,KLC2,TAP1,GATA3,PLXNA1,CCNB1,SLC20A1,ELMOD2,CENPN,NCS1,CHST2,SESN3,CTGF,ELMO2,ZFP36,IL31RA,STEAP2,AOX1,ATRNL1,TFG,RCAN3,LAMP2,PBK,CASP9,AGO4,PIF1,AURKB,SAV1,ZFAND5,ULK2,SGPP1,AHRR,AREG,PLK2,TBX1,NKD1,EIF4EBP2,UNC5B,TRAF5,DDX58,KLF2,INPPL1,HLA-E,DGKQ,KIF23,NOTCH2,SLC1A3,MECOM,ITGA3,CYR61,PIK3AP1,CTPS1,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,EEF1D,EPB41L5,DDB2,B9D2,MICB,AMER1,ANO6,CYFIP2,KDM3A,RASA1,FAS,DGKH,GABRD,PRKAG2,CSNK1G1,NR4A2,EFNA1,MAP3K5,IRF1,PLA2G4A,SLC2A4,TRIP10,S100A11,NLRX1,RPS6KA1,IQGAP1,EGR3,CD274,SNN,GNB2,APLP2,DOK4,CDKN1B,CNNM4,DAB2IP,IFIT1,LGMN,NR2C1,GPX4,CDKN2AIP,DMTN,SLC11A2,PRKCQ,AKR1E2,CMTM7,EPHA10,FYN,PPP2R5A,JAK1,STK26,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,RAB29,NR3C2,ATMIN,DENND5B,OTUD5,MRPS9,ARHGEF3,ARL4C,GPR180,APOBEC3H,SEPP1,LGALS3BP,TEAD3,RND1,FAM111A,OXCT1,PTEN,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,MAP3K7,CNPY3,GFI1,TRIM62,SPRY2,NCOA2,RASGRF1,SHMT1,ARAP2,MPP1,PARP4,FURIN,C1GALT1C1,GPLD1,RGS9,NUCB1,CTNS,PRDX3,GRIN2D,GPER1,ARSB,CPEB2,USP16,EMX1,CASP3,LTBP1,KIF2C,CACNB4,DNER,KREMEN1,TMC1,PTCHD4,SH3KBP1,ZCCHC12,TSPAN6,DPYSL2,DLG1,AKR1B1,KIF22,RAB20,MYH14,ARNT2,PTPRE,FGFR1OP2,RASGRP1,TDP1,SOD1,TRIM8,RNF165,ROR1,STK17B,ADRBK2,EDNRA,CXXC4,MDK,NEIL1,ARHGEF19,ADIPOR1,RAP1GAP,PPP2R5D,PSMC1,GRN,LRRFIP2,ATP6V1E2,PHLPP1,CA2,LRRN2,KCNN4,DIAPH2-AS1,FNIP1,KNTC1,HP1BP3,OXR1,HMG20B,BTN3A2,EGFR,FECH,GNAS,BCAR3,ONECUT1,TSC1,PLPP3,CGREF1,CDCA5,NFKBIA,RHOBTB2,PITPNA,YOD1,KLF7,GAS2L1,SLC25A24,SPC25,IL15,PSME2,SLC2A8,GMPR,ARHGEF16,SS18,SMO,RPN2,TWIST1,GOT1,PDIA6,LOXL1,F2R,HSPA2,FRS3,MAP3K3,BAG4,KREMEN2,ERBB2IP,DUSP4,DOCK5,MAP3K6,CANT1,CYP2U1,PLXND1,SGOL1,LIFR,ANXA3,SORT1,JKAMP,LRP4,AES,NOTUM,IL17RB,ADORA1,BRD7,IQGAP3,RAB3B,ADAM17,CENPC,NR4A1,DEPDC4,GCLC,POLD3,HLA-B,MARC1,PRCP,DHRS2,UBE2D2,HOXB13,GEM,ATP6V1C1,SOX8,L1CAM |
| 4.638e-07 | -14.58 | response to wounding | biological process | GO:0009611 | 747 | 161 | 16441 | 2455 |
MYL9,CASP3,KLC2,GATA3,F11R,ITPR2,KIF2C,CCNB1,VASH1,PDGFB,SDC1,KIF26A,CALM2,WEE1,CYP1A1,CTGF,STIM1,PIK3CA,IRF2,KIF22,FGFR1OP2,RASGRP1,TUBA4A,LAMP2,SOD1,KLK6,PRKAR2B,F12,ARF4,LCP1,OPTN,DPYSL3,MDK,PLCG1,KCNMB4,ARHGEF19,HPSE,HDAC1,HSPB1,F2RL1,MAFF,SERPINE2,ITGA6,DGKQ,CALM3,KIF23,RACGAP1,TEC,SLC1A3,DOCK11,MERTK,FBLN1,CORO1B,RAC2,ITGA3,TIMP1,CYR61,GATA2,FLRT3,PRKG1,WNT3A,DGKG,ELK3,CALM1,ANO6,HMG20B,PDE5A,SCRIB,SRSF5,ILK,GNA11,RHOB,PDE11A,RASGRP2,DGKH,GNAS,MATN2,ITPR1,DYSF,ATP1B3,CBX5,TRPC3,EHD1,IRF1,DOCK9,PLA2G4A,KIF3C,PAX6,PAPSS2,INPP5D,TP53,DGKA,ERBB2,PRKACA,DDR1,PDGFA,NOV,CYP4F11,PLCG2,CDH3,EPB41L4B,LMAN1,F2R,ENPP4,AKT1,PRKCQ,ATP1B1,ITPR3,CD40,MYL12A,FZD7,RTN4RL1,FYN,ABHD12,AXL,PTK7,NRG1,PRKAR1A,CD63,CTSB,HABP4,SDC4,SELL,TGFBR1,ETS1,FZD6,SIRPA,ITGA2B,PDCD10,CST3,BAX,CD9,ADAM15,ERBB3,AK3,SYK,ATP2B1,RHOA,ADAM17,PLSCR1,WNT10B,BCL9,PLAUR,PIK3R1,PPARA,C1GALT1C1,YES1,KIF11,BCAR1,DGKE,ARHGAP24,TIMP3,SERPINA1,ACVRL1,SYT7,PRCP,ARRB1,ITGAV,CENPE,HOXB13,L1CAM |
| 4.745e-07 | -14.56 | salivary_gland | COSMIC cancer mutations | salivary_gland | 1176 | 231 | 17775 | 2585 |
TNK1,ACVR1,HSPG2,SLC25A13,RET,PDGFRL,BAIAP3,SPTB,SLC9A7,CALM2,TYMP,WEE1,SIPA1L2,RPS6KA2,PQLC2,MUC4,CTNNB1,PAPSS1,DLG1,PIK3CA,ANKRD12,SEMA3G,ARNT2,ACOX2,PIK3CD,TFG,MYBL1,ERAP2,CCDC74A,ZNF462,NEK4,SMARCA2,TNIP1,LAP3,SERTAD4,PBK,AURKB,PRKRA,IDH1,CLCN2,GINS4,LCP1,FAM177A1,FASTKD1,MAP2,PLK2,ATP7B,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,TANC2,HOXC13,MRC2,RUNX2,CDK17,ZNF395,CHCHD7,NOTCH2,DOCK11,APBA1,RB1,IGF1R,PFKL,CD22,FRAS1,FCHO1,DAPK1,PRKCI,PRKG1,OPN3,MAP3K9,FNIP1,USP1,USP38,KNTC1,PIM1,CACNA1D,CNGA1,PIKFYVE,MAPK7,ALDH3A2,MPHOSPH9,USP31,ADCK3,PTPRH,PIP4K2C,SPATA13,BTN3A2,KIAA1109,KIF20B,EIF2AK1,PDK3,NFIB,EGFR,MAPKAPK2,TSC1,SEMA4D,DCK,NAB2,FGD6,NXPH4,AURKA,DYSF,SAMD8,MAP3K5,JAK3,CDAN1,TOB1,RPS6KA3,ADAMTS16,DMPK,MFSD3,SLC25A24,CAPN12,TRIP10,CAST,RPS6KA1,THRA,DGKA,TP53,ETNK1,ERBB2,GRK6,PRKACA,FLT3,DDR1,APPBP2,CDK14,MUC16,SP100,LHX6,TNPO2,BRI3,EPHB4,DLG3,LRP11,MYT1,SCYL3,FRS3,SEPHS1,MYO5B,MAP3K3,RFK,AKT1,COG2,CAPN6,SYNE2,UTRN,ERBB2IP,ATP1B1,TANC1,MAP3K6,NFIX,DUOX1,FYN,PTPRJ,JAK1,CDK19,PTK7,STK38,AXL,OVOL1,IRF7,KLF5,PDXK,AIFM3,ABCA1,LIFR,MAPK12,PRKAR1A,PINK1,TNRC6C,CENPI,GNE,FAM134A,NOTUM,SEPP1,TSPAN17,NEO1,SLC25A36,TMEM63A,DIRAS3,FOXP2,ANK1,CEP97,ITGB8,IRAK1,CDK16,PTEN,MGAT4A,TFAP2A,CKS1B,SGK1,MAPK11,IGFBP2,ERBB3,MAP3K7,SYK,CAMK2G,SUN2,ARHGEF28,CASK,B3GNT2,ARAP2,ELOVL3,PIK3R1,ZKSCAN2,AK4,MAML2,COL7A1,YES1,LRRC1,RNPEP,MAPK8IP1,DDX23,DCAF10,BTG1,FAT4,FGFR2,CCDC6,PKD2,CENPE,ZMIZ1,OSR1,TBC1D4,ESPL1,L1CAM,MELK |
| 4.773e-07 | -14.56 | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | 133 | 42 | 17758 | 2588 |
FAM171B,ZMAT1,TSC22D3,SCD5,BACE1,TMX4,HABP4,ARL4C,PBX3,TGFBR1,TGOLN2,SEPP1,PSIP1,BEX2,BMP2K,DNAJB9,SCML1,RASSF8,NOV,DPYSL2,TOX2,SGK1,ACSL4,SGCB,MYO5A,ALDH2,PQLC3,CTNNAL1,PRKCQ,ERP44,ZFAND5,ALCAM,RHOB,GABARAPL1,SOCS3,DNAJC10,RCAN2,ALG2,PER3,SLC31A2,PTGES,CYBRD1 |
| 4.868e-07 | -14.54 | tube morphogenesis | biological process | GO:0035239 | 343 | 86 | 16441 | 2455 |
ACVR1,GRHL2,LGR4,ST14,EPHA4,RET,GATA3,PRKACA,STIL,TP73,SETDB2,CTNNB1,NPNT,DACT1,LMO4,SMO,DLG1,TWIST1,DAB2IP,TACSTD2,PPP1CA,ETV4,DVL2,TFAP2C,DAG1,EDNRA,IRX3,ARHGAP35,AREG,SHROOM3,TBX1,PTK7,PLXND1,COBL,CTHRC1,NKX3-1,TMTC3,CCM2,SDC4,SOX9,RAB23,CTSZ,NCKAP1,FZD6,GBX2,CTNNBIP1,BMP2,VASP,GPC3,MEGF8,BMP7,BAX,MAP3K7,WNT3A,NTN1,SLC12A2,SPRY2,EPB41L5,HES1,TGIF1,SALL4,FMN1,DCHS1,PRICKLE1,SCRIB,KIF20B,NPHP3,ILK,NFIB,EGFR,BCL10,TSC1,NCOA3,FAT4,FGFR2,ACVRL1,CSF1,SPINT2,NR4A3,PKD2,SOX8,OSR1,SHOX2,RARG,FOXA1,ADAMTS16 |
| 4.898e-07 | -14.53 | VEGFA-VEGFR2 Pathway | REACTOME pathways | R-HSA-4420097 | 312 | 80 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,CTNNB1,ELMO2,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,AXL,PSMD3,MAP3K11,CTNND1,MAPK13,SPTBN5,NRG1,HSPB1,PSMC1,PPP2R5D,MAPK12,WASF3,RASA2,PSMD7,CALM3,PSMD10,NCKAP1,FGF19,DUSP5,ITGA2B,PAK2,MAPK11,ERBB3,NCAM1,PSMA5,CAMK2G,DUSP1,RASGRF1,RHOA,PSMB4,MAPKAPK3,RAPGEF2,PIK3R1,CALM1,GRIN1,CYFIP2,BCAR1,PSMA4,RASA1,EGFR,MAPKAPK2,FGFR2,ITPR1,FGF18,ARRB1,GRIN2D,ITGAV,JAK3 |
| 4.898e-07 | -14.53 | DELPUECH_FOXO3_TARGETS_UP | MSigDB lists | DELPUECH_FOXO3_TARGETS_UP | 69 | 27 | 17758 | 2588 |
KIF3C,TIMP2,CD55,KLK10,IGFBP6,KIAA0040,PLAUR,CTSB,SAT1,DUSP5,SPAG1,MXD1,IGF1R,GNB5,CYR61,PLCG2,BCL6,PIK3CA,DAPK1,CD9,CLDN4,KLF5,ERBB3,MAP3K5,SLC31A2,S100A13,GM2A |
| 5.145e-07 | -14.48 | positive regulation of programmed cell death | biological process | GO:0043068 | 566 | 128 | 16441 | 2455 |
CASP3,AGRN,GRIK2,RET,SUDS3,CAMK1D,SEPT4,HDAC6,BARD1,TP73,RPS6KA2,CTNNB1,CTGF,SIVA1,ALDH1A3,DNM2,PPP1CA,TIAM1,CYP1B1,SOD1,ACVR1C,CASP9,BNIP3L,PRKRA,SAV1,STK17B,VCP,ABR,DNM1L,PPP2R4,MAP3K11,KLF11,FGD1,BMF,ITGA6,ADAMTSL4,BMP2,TFAP4,CYR61,PAK2,DAPK1,PRKCI,MAP3K9,FNIP1,TNFRSF12A,WNT3A,ANO6,SCRIB,BCL2L13,RHOB,CDK5R1,FAS,STK17A,MAP3K5,RARG,XDH,DMPK,NQO1,INPP5D,TP53,P2RX7,COL18A1,BCL2L1,PHLDA1,AIFM2,BCAP31,ARHGEF16,SRPX,BCL6,CDKN1B,STEAP3,DAB2IP,EGLN3,F2R,SIRT1,PPIF,AKT1,RIPK2,SLC11A2,CD40,PTGS2,NGFRAP1,CDK19,ARHGAP4,BIN1,NKX3-1,PINK1,ARHGEF3,ARHGEF11,TRAF2,ARHGEF7,DAP,BIK,PDIA3,AES,TGFBR1,TOP2A,CARD8,PTEN,CTSC,MCF2L,BMP7,TFAP2A,BAX,PLEKHF1,BUB1,ITM2C,OSGIN1,DUSP1,RHOA,WNT10B,PLAUR,RAPGEF2,RGCC,GRIN1,TRIM35,GPLD1,BCL10,BTG1,CASP7,NR4A3,E2F1,ARRB1,GPER1,ARHGEF9,MELK,NGEF,ARHGEF4 |
| 5.195e-07 | -14.47 | positive regulation of cellular protein metabolic process | biological process | GO:0032270 | 1430 | 279 | 16441 | 2455 |
TXN,ACVR1,TRIM5,DNAJC3,RET,XIAP,CUL1,NRG2,PSME1,IL18,CCNB1,SEPT4,SNX9,CARD10,PHF1,GRM5,TP73,CALM2,PAK6,PSMD1,CTGF,IL31RA,PIK3CA,NEK4,VPS11,ACVR1C,CASP9,SPRTN,PRKAR2B,F12,RNF19B,PIAS3,PLCG1,ANKRD6,PLK2,TBX1,PPP2R4,NOD2,MAP3K11,F2RL1,GAB1,SOX9,PRKAA1,TFAP4,CYR61,DAPK1,MAP3K9,MYDGF,NCAM1,SOCS5,MMD,MFI2,MAPKAPK3,CALM1,PYM1,CYFIP2,ILK,PSMA4,RASA1,FAS,FNTA,PRKAG2,SEMA4D,PELI2,AURKA,STK39,EFNA1,GDF11,MAP3K5,XDH,SPRED1,DLGAP5,IQGAP1,PRKACA,FLT3,CCND1,ST5,RALB,CDKN1B,DAB2IP,OSBPL7,RASGEF1A,PSRC1,RIPK2,FZD4,CDCA2,SLC11A2,FZD7,IRS2,FYN,JAK1,PPP2R5A,NGFRAP1,STK26,WFS1,KIAA1804,SLC27A1,NRG1,ARNT,MAPK12,PRKAR1A,PCOLCE,TAOK2,NKX3-1,TRAF2,SDC4,FLOT1,PKN1,FGF19,ICAM1,PDCD10,IRAK1,RNF128,CTSC,PTEN,KNDC1,BAX,MAPK11,ERBB3,MAP3K7,SPRY2,RASGRF1,PDGFC,RAPGEF2,NUB1,EIF5A2,GRIN1,FURIN,YES1,GPLD1,FGFR2,ACVRL1,RYK,GRIN2D,GPER1,LRRK1,CENPE,FZD5,CD81,ESPL1,USP16,JARID2,CCNC,CASP3,CAMKK1,EPHA4,ARFGEF1,NENF,ERP29,PDGFB,SPTB,FANCI,CTNNB1,SHC3,NPNT,IL6ST,PSMC2,PASK,DLG1,TNFRSF18,SLC39A10,RASGRP1,PLK1,SOD1,EZR,CDK1,VCP,GPRC5B,MADD,PRKCDBP,CAB39,PSMC1,PPP1R12A,RASA2,DNAJB2,PSMD7,CALM3,SORBS3,TEC,FBLN1,DUSP5,BMP2,RB1,IGF1R,PAK2,FNIP1,BRAT1,MDFIC,NPTN,PIM1,WNT3A,PSMA5,CCDC88A,MDFI,STRADB,PDE5A,BCL2L13,CDK5R1,EGFR,BCAR3,MAPKAPK2,INSR,CSF1,PLPP3,NFKBIA,DCUN1D1,JAK3,CTBP1,PROM2,AVPI1,UPF3B,IL15,PSME2,TP53,P2RX7,ERBB2,RASGRP3,CCNL1,STIL,EMP2,BCAP31,PDGFA,KIF14,BCL6,EGLN3,F2R,HSPA2,DVL2,UPF3A,CHP1,FRS3,SIRT1,MAP3K3,BAG4,TIMP2,AKT1,CDC20,CD40,MAP3K6,PSMD3,SPTBN5,EFNA5,CNEP1R1,PINK1,TAB3,SH3D19,DAP,PSMD10,GDF15,TGFBR1,TRIB2,CARD8,ADORA1,BMP7,BRD7,IQGAP3,SYK,CAMK2G,HES1,RHOA,ADAM17,PSMB4,PLAUR,GCLC,RGCC,PRICKLE1,MPV17L2,BCL10,CASP7,BANK1,RAP2C,FGF18,NMI,TADA2B,ARRB1,PKD2,PPP2R3C,UBE2C,NDFIP1 |
| 5.270e-07 | -14.46 | PROTEIN_MODIFICATION_PROCESS | MSigDB lists | PROTEIN_MODIFICATION_PROCESS | 624 | 136 | 17758 | 2588 |
TNK1,ACVR1,SSH1,RET,FBXO2,HDAC6,PICK1,DAPK2,CDKL5,P4HB,IL31RA,FUT1,DUSP10,PPP1CA,PTPRE,METAP2,NEK4,PTPN18,MARK1,RNF11,GALNT7,LOXL2,ICMT,STK17B,DOLPP1,LIMK1,MYLK,PPP2R4,MAP3K11,POMT1,PCSK5,PRKAA2,CDK17,PRKAA1,MERTK,TSPAN7,DUSP5,RABGGTA,B3GALNT1,IGF1R,PAK2,MAP3K9,DAPK1,TPST1,PRKG1,PRKCI,STT3B,PIM1,MYLIP,GAD1,CCDC88A,NAGPA,PIGC,DDB2,QSOX1,PTPRH,MGAT4B,STRADB,EIF2AK1,ILK,EGFR,NMT2,STK17A,MAPKAPK2,MMP15,TSC1,FNTA,INSR,AURKA,ALG2,JAK3,CTBP1,DMPK,NF2,HDAC11,TESK2,ERBB2,MAPK4,EPM2A,CCND1,PPME1,PLK4,RPN2,PHKA2,LOXL1,F2R,SEPHS1,MAP3K3,SIRT1,AKT1,COG2,PTPRU,PTPN9,DUSP4,CBL,MAP3K6,PTPRJ,STK38,STAT1,KIAA1804,MAPK12,DYRK3,PINK1,MAN1A2,TGFBR1,POMGNT1,TRIB2,SBF1,PKN1,PPP2R3A,WWP2,FUT2,CDK16,PTEN,MGAT4A,FUT8,SGK3,SGK1,WWP1,ERBB3,SLC35A1,GCNT1,AMFR,FURIN,PARP4,YES1,BCL10,TXK,PRDX4,PLOD2,ACVRL1,NR4A3,PLOD3,CD81,UBE2C,HIPK3 |
| 5.312e-07 | -14.45 | GABRIELY_MIR21_TARGETS | MSigDB lists | GABRIELY_MIR21_TARGETS | 279 | 72 | 17758 | 2588 |
TRIM2,ARMCX3,SUZ12,EPHA4,ETNK1,ARFGEF1,FAM102B,RASGRP3,MPP5,FANCI,ACAP2,FAM46A,CNTRL,OSBPL3,DDHD2,DLG1,RP2,BTBD3,RASGRP1,SYNE2,UTRN,SLC17A5,SESN1,SFXN1,ZNF367,HOXA9,SLC9A6,KLF5,EIF4EBP2,GLCCI1,LIFR,RMND5A,GNE,PM20D2,NFAT5,TOP2A,SNX13,B3GALNT1,CEP97,ITGB8,RALGPS2,MGAT4A,CALD1,AIM1,MSH2,EXOC8,LIMCH1,ZRANB1,PARP9,ACBD5,PHF20L1,TACC1,LPGAT1,PIK3R1,PPARA,PRRC1,NFIB,DCAF10,DDAH1,TIMP3,RAB11FIP2,FAM3C,CLIP4,PKD2,YOD1,PLD1,PER3,OSR1,CYBRD1,SNX30,RPS6KA3,ESYT2 |
| 5.312e-07 | -14.45 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | 279 | 72 | 17758 | 2588 |
CCNE2,PAPSS2,DLGAP5,IL15,NDC80,ETNK1,NUF2,CD274,FANCI,RCN1,PCNA,CCNA2,NPNT,DPYSL2,SLC44A1,ARNT2,MINPP1,DOCK4,FIGNL1,PBK,NUSAP1,ANLN,CCNF,IDH1,CDK1,FZD7,SFXN1,PTGS2,FASTKD1,ZNF367,STAT1,KIF23,RACGAP1,PM20D2,ZNRF3,PGAP1,SSX2IP,SCML1,TOP2A,CTSC,CENPJ,CALD1,PRC1,DRAM1,ACTA2,GAD1,MPHOSPH9,CKAP4,SMC4,SOCS5,NFE2L3,ADAMTS2,PHF20L1,CASK,ZWINT,ZNF84,EIF5A2,VEZT,KIF11,ANKRD29,FAS,TWSG1,OTUD6B,NFKBIA,SLC25A40,ERAP1,ITGAV,CENPE,NDE1,WDR91,IFIH1,MELK |
| 5.377e-07 | -14.44 | positive regulation of apoptotic process | biological process | GO:0043065 | 561 | 127 | 16441 | 2455 |
CASP3,NQO1,AGRN,GRIK2,INPP5D,RET,SUDS3,TP53,COL18A1,P2RX7,BCL2L1,CAMK1D,SEPT4,AIFM2,BARD1,PHLDA1,BCAP31,ARHGEF16,TP73,RPS6KA2,CTNNB1,CTGF,SRPX,SIVA1,ALDH1A3,BCL6,DNM2,CDKN1B,DAB2IP,STEAP3,PPP1CA,EGLN3,TIAM1,F2R,CYP1B1,PPIF,SIRT1,SOD1,RIPK2,AKT1,ACVR1C,CASP9,BNIP3L,SLC11A2,CD40,PRKRA,SAV1,STK17B,VCP,ABR,PTGS2,DNM1L,CDK19,NGFRAP1,PPP2R4,MAP3K11,KLF11,ARHGAP4,FGD1,BIN1,ARHGEF3,PINK1,BMF,NKX3-1,ARHGEF11,DAP,ITGA6,ARHGEF7,TRAF2,BIK,PDIA3,TGFBR1,AES,ADAMTSL4,BMP2,TOP2A,TFAP4,CARD8,CYR61,CTSC,PTEN,BMP7,MCF2L,PAK2,DAPK1,BAX,TFAP2A,PRKCI,MAP3K9,PLEKHF1,FNIP1,BUB1,TNFRSF12A,WNT3A,ITM2C,OSGIN1,DUSP1,RHOA,WNT10B,RAPGEF2,PLAUR,ANO6,GRIN1,RGCC,SCRIB,TRIM35,BCL2L13,RHOB,CDK5R1,FAS,BCL10,STK17A,GPLD1,BTG1,CASP7,E2F1,NR4A3,ARRB1,GPER1,MAP3K5,RARG,ARHGEF9,MELK,ARHGEF4,XDH,NGEF,DMPK |
| 5.449e-07 | -14.42 | HALLMARK_INTERFERON_ALPHA_RESPONSE | MSigDB lists | HALLMARK_INTERFERON_ALPHA_RESPONSE | 94 | 33 | 17758 | 2588 |
PARP12,IL15,PARP14,TRIM5,PSME2,TAP1,GMPR,SELL,PSME1,SAMD9,HERC6,LGALS3BP,FAM46A,TRIM21,IRF2,HLA-C,PARP9,LAMP3,MX1,RIPK2,PLSCR1,LAP3,IFITM3,USP18,NUB1,IFIT3,CSF1,NMI,TDRD7,IRF7,CMPK2,IFIH1,IRF1 |
| 5.476e-07 | -14.42 | GSE6269_HEALTHY_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_STREP_PNEUMO_INF_PBMC_DN | 166 | 49 | 17758 | 2588 |
GRN,MYL9,COL9A3,SORT1,LGALS3,ARHGEF11,CD63,CAST,BLVRB,IL13RA1,ITGA2B,SIRPA,GNS,CTNNBIP1,APLP2,ZYX,BCL6,STEAP3,MARCH2,CRTAP,CKAP4,EPHX1,CYP1B1,CPD,PPIF,LAMP2,QSOX1,BAG4,TIMP2,PLAUR,BNIP3L,VAMP3,FURIN,CDA,MCFD2,RNF19B,FOS,SOCS3,H1F0,FGFR2,PELI2,DYSF,ADIPOR1,ANXA9,ZMIZ1,PLIN3,SERPINB1,CYBRD1,CD33 |
| 5.483e-07 | -14.42 | DELACROIX_RARG_BOUND_MEF | MSigDB lists | DELACROIX_RARG_BOUND_MEF | 357 | 87 | 17758 | 2588 |
LTBP1,SLC25A24,AVPI1,PRSS22,FTH1,F11R,CARD10,LTBP3,EPS8L2,PICK1,CCND1,ST5,CTGF,SH3BP1,DOK4,OSBPL3,AOX1,CTTN,LOXL1,CDKN2D,CERS2,OLFML2A,SNTB2,COQ10B,S100A4,SAT1,LOXL2,DUSP4,PLEKHB1,DPYSL3,GABARAPL1,OSBPL2,ARHGEF19,SLC25A4,GDE1,PEX2,WWTR1,MAPK13,ANXA9,DMWD,OTUD5,PRSS8,NUDT6,PCOLCE,INPPL1,CTSB,ADO,GDF15,NDUFA4,PKN1,CRABP2,DHRS3,H1FX,IRF2BPL,CALR,KIF5B,ADD3,ZNRF2,NEK2,SGK1,TNFRSF12A,TAGLN2,CTSD,ALS2CL,DUSP1,SUN2,WNT10B,FURIN,DPP9,CAPNS1,MPV17L2,PRX,TIMP3,CTNS,RCBTB2,FGFR2,RND3,FGF18,RHOBTB2,EFNA1,HMGA1,ACADM,OSR1,UBE2C,NDFIP1,RARG,DMPK |
| 5.502e-07 | -14.41 | UDAYAKUMAR_MED1_TARGETS_DN | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_DN | 224 | 61 | 17758 | 2588 |
INPPL1,PPP1R12A,REPS2,ZNF395,CDKN1C,NDRG1,TSC22D3,FAM134A,EFHD2,PHLPP1,MAP1LC3B,DDR1,C11orf95,TNFSF9,DUSP5,DNAJB9,ELF3,PTEN,KCNN4,FAM13B,MAP3K9,BAX,KANK2,EPHB4,PIM1,EPB41L4B,CITED2,TMBIM1,CTH,AMOTL2,DDB2,ADAM17,SAT1,CDA,NFE2L1,CCNF,KDM3A,RHOB,FRMD4B,GABARAPL1,SOX13,FAS,MAPKAPK2,GNAS,BTG1,TIMP3,ETS2,NR1D2,H1F0,RCBTB2,AXL,P4HA2,PLK2,ERAP1,CANT1,EFNA1,FHL1,SPCS3,LIFR,HOXC13,EHD1 |
| 5.578e-07 | -14.40 | purine ribonucleoside triphosphate binding | molecular function | GO:0035639 | 1785 | 337 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,KIF13A,PIF1,AURKB,RAB2B,ARF4,ULK2,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,TRANK1,RALB,FICD,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,GALK1,HSP90B1,TAOK2,ATP9A,ARL4C,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,OPLAH,PCCB,CASK,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PSMC2,PAPSS1,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,PSMC1,RRAGD,PRKAA2,LMTK3,RUNX2,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ABCC1,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,DYRK3,PINK1,TOR4A,SHPRH,CIT,GNAL,GNE,ERCC6L,TGFBR1,KIF5B,TOP2A,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,MYO5A,ATP2B1,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,RAP2C,UBE2D2,GEM,UBE2C,HIPK3,ABCG1 |
| 5.598e-07 | -14.40 | LE_EGR2_TARGETS_UP | MSigDB lists | LE_EGR2_TARGETS_UP | 107 | 36 | 17758 | 2588 |
CDKN1C,CDCA8,KIF23,COL18A1,KIF2C,CCNB1,ETS1,CCND1,TOP2A,CCNA2,UBE2T,REEP1,PRC1,PLK4,CKS1B,KIF22,BUB1,USP1,IQGAP3,CKS2,PLK1,P2RX4,KIF20A,FIGNL1,PLEKHO1,CDC20,EZR,NUSAP1,KIF11,CDK1,RBL1,CORO1C,AURKA,KPNA2,CCNB2,CSRP2 |
| 5.600e-07 | -14.40 | REACTOME_AXON_GUIDANCE | MSigDB lists | REACTOME_AXON_GUIDANCE | 239 | 64 | 17758 | 2588 |
MYL9,AGRN,RPS6KA1,ERBB2,PLXNA1,CACNB4,SPTB,PAK6,RPS6KA2,ARTN,DPYSL2,DLG1,DNM2,NTN4,MYH14,SCN2A,DLG3,COL6A2,EZR,PRKCQ,ALCAM,CDK1,DPYSL3,ARHGAP35,PLCG1,FYN,LIMK1,SPTBN5,PLXND1,UNC5B,MYL12B,SCN5A,COL9A3,ARHGEF11,COL4A5,NRP2,ITGA2B,NEO1,RND1,RAC2,ANK1,VASP,COL6A1,PAK2,NTN1,NCAM1,FARP2,DPYSL5,RHOA,RGMB,DPYSL4,RANBP9,CDK5R1,RHOB,EGFR,CNTNAP1,SEMA4D,PITPNA,ITGAV,SEMA3A,TRPC3,L1CAM,RPS6KA3,RGMA |
| 5.837e-07 | -14.35 | GSE7852_LN_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_DN | 195 | 55 | 17758 | 2588 |
INPPL1,FARP1,TXN,KIAA1462,S100A11,IQGAP1,SOD2,CYB561,KCTD12,BCL2L1,DUSP5,BEX2,ZNF212,MECOM,IER3,PLS3,BTG3,KHNYN,RNF128,SLC16A6,KCNK5,FOSB,SORL1,TAX1BP3,TNFRSF18,MDFIC,AHCY,HSPA13,TAGLN2,KLF9,TMEM64,SEMA3G,TMBIM1,NR4A1,PTPN9,CORO2A,S100A4,PYGL,RUNX3,PRKRA,RNF19B,C3orf58,STX3,DGKE,SLCO4A1,MPRIP,NGFRAP1,ABCB1,NR4A2,PKD2,NFKBIZ,LRRK1,FHL1,TTC39C,TOB1 |
| 5.936e-07 | -14.34 | RTAAACA_V$FREAC2_01 | MSigDB lists | RTAAACA_V$FREAC2_01 | 871 | 179 | 17758 | 2588 |
TRIM2,HSPG2,GRIK2,TSC22D3,PNPLA2,KLC2,ARFGEF1,DHX8,NDRG2,CAMK1D,PDGFB,CMTM6,PLS3,WEE1,SESN3,HSF2,CTGF,GRHL1,MKRN3,IL6ST,KLF3,MITF,DUSP10,WBP4,BTBD3,TIAM1,STK35,METAP2,SMARCA2,TRIM8,ING1,CXXC5,TNIP1,ACVR1C,SERTAD4,RGAG1,ROR1,SLC25A5,MDK,TRIM9,TBC1D17,KLF12,MYLK,SH3GLB2,EIF4EBP2,SPRY4,LEMD1,STARD13,MAFF,PCSK5,FAM89A,RMND5A,LASP1,FRMD4A,PPP1R12A,CDKN1C,CHCHD7,ETV5,ASAH1,PHLPP1,DHRS3,TNFRSF19,MECOM,BMP2,TFAP4,IGF1R,FRY,RALGPS2,CYR61,SLC16A6,FLRT3,VASN,ZRANB1,NTN1,PLCB2,KCNJ12,ELK3,KIF20A,ADCK3,MGAT4B,FHL2,TCF7,BCL2L13,UNC45B,ZDHHC3,RANBP9,NFIB,DCP2,TSC1,INSR,PLEKHH2,TIMM8A,KBTBD2,PELI2,MATN2,NR4A2,IFIH1,RARG,TOB1,EGLN1,RAD21,SLC2A4,NDRG1,THRA,WDTC1,ERBB2,P2RX7,KCTD12,BLCAP,GRK6,OSR2,PRKACA,GNB2,ART5,ZFYVE9,ZNF385B,CDK14,CCND1,KCTD15,LMO4,CDKN1B,DAB2IP,MYT1,CTH,TMCC2,PANK1,CLSTN1,DUSP4,DOCK5,NIN,NFIX,FYN,PDLIM3,AXL,STAT6,PPP1CB,TLE1,NRG1,C1orf43,REEP4,LIFR,ABCA1,FAM134B,BIN1,IGFBP6,BIK,FAM134A,ZNF219,SEPP1,ETS1,PPP2R3A,COX7A2,NEO1,CD109,FOXP2,SNX13,RNF128,CALD1,BUB1,KLF9,CITED2,CLIP2,DUSP1,PDGFC,TGIF1,NR3C1,NR4A1,LRRC1,NPDC1,FOS,CRTC2,PITX2,GALNT3,ABCB1,OSR1,SHOX2,OCLN,PKIA,NGEF |
| 5.937e-07 | -14.34 | ruffle | cellular component | GO:0001726 | 156 | 47 | 17570 | 2579 |
DDX58,MTM1,PACSIN2,ARAP3,NF2,S100A11,CIT,ARHGEF7,IQGAP1,EPS8,SNX9,EPS8L2,INPP5E,RINL,CDKL5,DNM2,TNFRSF12A,CTTN,TLN2,PACSIN1,SPRY2,S100A6,MYO5A,EPB41L5,RHOA,ADAM17,SPATA13,EZR,AIF1L,BCAR1,ARF4,ARHGEF26,RASA1,LCP1,FRMD4B,RASGRP2,GNAS,KLHL2,PLCG1,PTPRJ,FGD6,ITGAV,SPRY4,ARF6,COBL,ARHGEF4,FGD1 |
| 5.967e-07 | -14.33 | Pkinase | pfam domains | PF00069 | 352 | 88 | 16629 | 2504 |
ACVR1,CAMKK1,RPS6KA1,MAPK4,CAMK1D,GRK6,PRKACA,CDK14,PAK6,DAPK2,WEE1,RPS6KA2,CDKL5,PASK,PLK4,SCYL3,STK35,MAP3K3,NEK4,PLK1,MARK1,AKT1,PBK,PRKCQ,PKMYT1,AURKB,MAP3K6,STK17B,ADRBK2,CDK1,ULK2,STK26,CDK19,PLK2,STK38,MYLK,MAPK13,RNASEL,MAPK12,PRKAA2,TAOK2,DYRK3,PINK1,CDK17,NUAK1,CIT,PRKAA1,TGFBR1,TRIB2,PKN1,BMP2K,ADRBK1,IRAK1,CDK16,PAK2,PRKCI,SGK3,NEK2,MAP3K9,PRKG1,DAPK1,SGK1,MAPK11,BUB1,PIM1,MAPK7,MAST4,PHKG2,CAMK2G,CASK,MAPKAPK3,STRADB,EIF2AK1,PIM3,PDIK1L,STK17A,MAPKAPK2,CSNK1G1,AURKA,STK39,CDK18,LRRK1,MAP3K5,NRBP1,HIPK3,MELK,RPS6KA3,DMPK |
| 6.096e-07 | -14.31 | HAN_SATB1_TARGETS_UP | MSigDB lists | HAN_SATB1_TARGETS_UP | 379 | 91 | 17758 | 2588 |
GAA,LZTFL1,TNK1,ATP8A1,FBXO2,LMCD1,ERBB2,F11R,SDF4,FANCI,CDS1,FAM46A,CTGF,METTL7A,FICD,PPME1,KLF3,CLDN4,LGMN,CYP1B1,COL6A2,CAPN6,S100A4,SAT1,TNS1,LDB2,SEC14L2,ENPP1,AREG,ANKRD6,PTK7,SECTM1,NRG1,RCAN2,TMEM8B,NR3C2,ATMIN,RRAGD,RUNX2,ZNF395,ALDH6A1,ITGA6,CTSB,CALB2,SOX9,NES,CRABP2,SEPP1,S100A2,H1FX,LMNA,MECOM,ITGA3,FAM20C,KCNN4,FUT8,TOX2,ADAM15,ABCD1,TSPAN13,LIMCH1,ERBB3,MAST4,GAD1,SLC16A5,ALDH3A2,DUSP1,PIGC,HMGN5,MPP1,AMFR,CXorf57,AK4,CYFIP2,IFIT3,EGFR,FUCA1,PELI2,MATN2,SPINT2,CCDC69,ARRB1,OSMR,DYSF,FHL1,HMGA1,SHROOM2,RARG,ZBTB33,PKIA,KLF7 |
| 6.097e-07 | -14.31 | lymph_node | COSMIC cancer mutations | lymph_node | 1781 | 330 | 17775 | 2585 |
FAM171B,ACVR1,GRIK2,ATP8A1,RET,GATA3,NRG2,PDGFRL,MORF4L2,SEPT4,BARD1,FAM46C,KIF26A,SLC20A1,SLC35E4,WEE1,MUC4,CTGF,CYP2S1,RDH14,AOX1,STEAP2,PIK3CA,DNM2,ATRNL1,PIK3CD,TMEM37,RCAN3,TFG,NEK4,SPEF2,PBK,AURKB,LDB2,LCP1,ARHGEF26,PLCG1,GRID2IP,DNM1L,PLK2,MYLK,MAP3K11,PRDM5,MAPK13,ARF6,HOXC13,KLF2,MRC2,CDK17,CDKN1C,ITGA6,PRKAA1,SLC1A3,NOTCH2,TSPAN7,PRRG4,SH3RF2,FRY,FAM189A1,CD22,DAPK1,PRKG1,MAP3K9,SLAIN2,CD70,CACNA1D,PIKFYVE,MAPK7,ZNF117,RIMS2,EPHX1,TRAK2,GCC2,ADCK3,SALL4,DCHS1,PIP4K2C,MYBL2,WHSC1,KIF20B,SFXN5,PDE11A,FAS,ISM1,PELI2,DCK,ITPR1,PIAS2,CLMN,AURKA,MAP3K5,RPS6KA3,EGLN1,DMPK,IRF1,SPRED1,RPS6KA1,IQGAP1,ETNK1,IRX4,GRK6,PRKACA,FLT3,DDR1,APC2,CDS1,UHRF1BP1L,CCND1,MUC16,SCNN1A,EPHB4,RASGEF1A,DLG3,SNX10,MYO5B,MX1,UTRN,ATP1B1,CBL,SP4,NIN,PRDM11,FYN,PPP2R5A,JAK1,PDLIM3,SHROOM3,CDK19,WFS1,AXL,WWTR1,ZNF704,MLKL,PDXK,NR3C2,MAPK12,PRKAR1A,ARHGEF3,FAM189A2,PARP14,JRKL,ATP9A,EPS8,SLC25A43,ETS1,NEO1,SLC25A36,DIRAS3,IRAK1,PTEN,KCNK5,FAM102A,SLC44A2,MAPK11,ERBB3,RAG1,MAP3K7,CNOT6L,SGCB,MSH6,RASGRF1,CASK,LCA5,ARAP2,FAM160A1,PIK3R1,CXorf57,UBE2A,AK4,UBAC1,YES1,GRTP1,KIF11,DCAF10,BTG1,RPL12,PLOD2,FGFR2,CCDC6,ETAA1,ITGAV,TLL2,EXPH5,LTBP1,TNK1,CUL4B,ITPR2,KREMEN1,SPTB,SH3KBP1,ZFYVE16,RPS6KA2,CTNNB1,P4HB,SHC3,CDKL5,PAPSS1,ANKFN1,DLG1,NFU1,CTTN,ARNT2,PTPRE,MYRIP,IL1RAP,ZNF462,TRIM8,ASXL1,SYNE3,RGAG1,PRKRA,IDH1,SESN1,ZBTB7B,PTGFRN,TBC1D17,NEIL1,FASTKD1,MADD,TDRD7,ARRDC1,PRKCDBP,PIK3C2B,PPP2R5D,CAPN1,PCSK5,CD99,ARAP3,ETV5,PM20D2,SAMD9,CNTNAP2,ADAMTSL4,ANO1,MYO5C,ZNF432,RB1,UBE2Q2,IGF1R,PFKL,FNIP1,PIM1,NCEH1,ETV7,CHSY3,PARD3B,TCF7,EIF2AK1,PDK3,EGFR,PRX,MAPKAPK2,DHDH,TMEM30A,UTP14C,NFKBIA,KIF12,JAK3,COL16A1,KLF7,LMO7,LZTFL1,NF2,IL15,TMX4,DGKA,TP53,COL18A1,ERBB2,TDRKH,MICALL2,PER2,CDK14,PLCG2,BCL6,NFKB2,PDIA6,SCYL3,SEPHS1,MAP3K3,RFK,AKT1,TMTC2,DUSP4,DOCK5,MAP3K6,STAT6,STK38,PTK7,XRCC3,SPTBN5,SYT13,ARHGAP4,ABCA1,LIFR,PINK1,GNE,HAL,MCTP2,FOXP2,MDM1,ADRBK1,CDK16,BMP7,CKS1B,SGK1,FAIM,SYK,CAMK2G,SYPL1,RHOA,RAB3B,PSMB4,NR3C1,OGDHL,MAML2,TRIM35,BBS2,MAPK8IP1,BCL10,ARHGAP24,HLA-B,FAT4,SERPINA1,TRIM69,ZNF214,SH3BGRL2,GRAMD1C,ATP6V1C1,TBC1D4 |
| 6.112e-07 | -14.31 | carbohydrate metabolic process | biological process | GO:0005975 | 829 | 175 | 16441 | 2455 |
SLC35D2,GAA,UGT8,AGRN,HSPG2,GNPDA1,SLC25A13,HEXB,NANS,GALM,MGAT5B,SDC1,CHST2,CHPF,CALM2,INPP5E,NUP210,MUC4,IL6ST,IMPAD1,PAPSS1,PIK3CA,FUT1,AKR1B1,PPP1CA,TFG,TIPARP,MGAT5,SLC35C1,MGAM,SLC17A5,GALNT7,MCFD2,IDH1,ARF4,VCP,MAN2A2,HS6ST1,HPSE,UEVLD,AREG,DOLPP1,GNPTAB,DHTKD1,GLA,ITPKA,POMT1,PPP2R5D,DLAT,INPPL1,PPP1R2,PRKAA1,CALM3,ISYNA1,B4GALT4,ADAMTSL4,KIAA1161,B4GALNT1,GNS,CALR,B3GALNT1,PFKL,BRAT1,STT3B,NUP85,PHKG2,PPP6R1,TMED2,TRAK2,CHSY3,NAGPA,GFPT1,B3GNT7,CALM1,MGAT4B,GYLTL1B,PYGL,PDK3,PKM,GLT8D2,CYB5A,GLCE,DHDH,ONECUT1,PRKAG2,INSR,UAP1,DGAT2,MDH1,CTSA,B4GAT1,ALG2,NUP58,SLC2A4,UGP2,PAPSS2,GALNT12,SLC2A8,WDTC1,PRKACA,EXT2,ART5,EPM2A,PER2,MUC16,GYS1,GLB1L2,RPN2,GOT1,PHKA2,LMAN1,NAGA,GM2A,CHP1,SIRT1,SEC23A,AKT1,PFKFB2,GLO1,B3GALNT2,IRS2,ALDH5A1,DDOST,PPP1CB,HS3ST3B1,B4GALT3,ST3GAL1,POMGNT2,MAN2B2,CMAS,GALK1,TRAPPC10,ENO2,MAN1A2,SDC4,GNE,PDIA3,CTSZ,DSE,POMGNT1,FUT2,CTSC,PTEN,MGAT1,A4GALT,MGAT4A,ALG13,GPC3,GALNS,FUT8,UBE2J1,SLC35A1,GCNT1,HMMR,B3GALT6,PGM1,MLEC,B3GNT2,ALDH2,GUSB,GCLC,PARP4,OGDHL,C1GALT1C1,COL7A1,CRTC2,GALNT3,FUCA1,SERPINA1,SLC35B3,CSGALNACT1,PGM2L1,GLB1,NUP37,ARSB |
| 6.119e-07 | -14.31 | LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | MSigDB lists | LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | 103 | 35 | 17758 | 2588 |
FAM171B,ANXA3,TRIM2,KLK10,PINK1,SOX9,SAMD9,EGR3,PLA2G16,B4GALT4,SLC20A1,DUSP5,MXD1,SYTL2,ELF3,MUC16,CTGF,GRHL1,ALDH1A3,DAPK1,FUT1,MYH14,ERBB3,C10orf54,MYO5B,TACC1,PLEKHA7,ARHGDIB,KLK6,SLC17A5,AIF1L,PTGS2,INPP4B,RAB11FIP1,VSIG10 |
| 6.119e-07 | -14.31 | SUNG_METASTASIS_STROMA_UP | MSigDB lists | SUNG_METASTASIS_STROMA_UP | 103 | 35 | 17758 | 2588 |
GAA,PINK1,AGRN,HSPG2,XYLT1,ETV5,EPS8,SDC4,PDIA5,CRABP2,SPSB1,SSX2IP,CD46,CALR,LMO4,RFX5,CLIP2,CTDSP2,SOCS5,CD55,BNIP3L,FURIN,PTGFRN,ALCAM,COL12A1,PTGS2,TIMP3,KCNK1,PLOD2,PLK2,UACA,FHL1,CD81,CPEB2,IFI6 |
| 6.134e-07 | -14.30 | CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | 205 | 57 | 17758 | 2588 |
WASF3,LASP1,PACSIN2,TAOK2,SORBS1,ARAP3,NF2,SSH1,KIF23,TESK2,RACGAP1,MRAS,PLD2,SORBS3,KIF2C,CNTROB,APBA1,RND1,CKAP5,ARHGEF10L,KIF5B,AP1M2,CENPJ,KIF13B,TUBGCP6,CAPG,DLG1,PRC1,PRKG1,TUBG1,CCDC88A,SUN2,SOD1,MARK1,RHOA,DSTN,UXT,EZR,NUSAP1,ARHGDIB,ANLN,BCAR1,KIF11,NUBP1,RASA1,TSC1,MID1IP1,RND3,LIMK1,MAP3K11,ARAP1,FGD6,KPNA2,ARF6,ARHGAP4,SHROOM2,FGD1 |
| 6.265e-07 | -14.28 | myelodysplastic_syndrome | COSMIC cancer mutations | myelodysplastic_syndrome | 1210 | 236 | 17775 | 2585 |
LTBP1,GAA,TNK1,ACVR1,CRYM,CAMKK1,EPHA4,RET,DHX8,GATA3,UBE2Q1,TEX2,CAMK1D,KIF26A,SLC20A1,DNER,TMC1,GRM5,PLS3,CDKN2C,NKAIN3,PAK6,DAPK2,WEE1,RPS6KA2,NUP210,TGFBR3,MUC4,CTNNB1,CDKL5,DNAH6,SHC3,ANKFN1,IL31RA,PIK3CA,ATRNL1,RGS5,NTN4,CRY2,SLC39A10,STK35,CCDC74A,PLK1,NEK4,MCTP1,MARK1,ACVR1C,ASXL1,PBK,ROR1,AURKB,LDB2,IDH1,ADRBK2,STK17B,ULK2,KCNK1,PLK2,LIMK1,MYLK,TRAF3IP1,MAP3K11,MAPK13,RNASEL,APBA2,PDPR,GAB1,PRKAA2,CDK17,FRMD4A,PRKAA1,ADCK5,CNTNAP2,SAMD9,MERTK,BMP2K,MECOM,MYO5C,ATG4A,CALR,RB1,CA2,IGF1R,PIK3AP1,GATA2,BDH1,NEK2,DAPK1,PRKCI,PRKG1,ADCK2,MAP3K9,FNIP1,CADPS2,ALPK1,PIM1,CACNA1D,MAPK7,PHKG2,KDELR1,ADCK3,TESK1,STAT4,FHL2,STRADB,VEZT,EIF2AK1,PDK3,PDIK1L,C3orf58,NFIB,EGFR,PDE11A,STK17A,GNAS,MAPKAPK2,CACHD1,NAAA,INSR,MPP2,RAB31,ALPK3,AURKA,CABIN1,CDK18,LTBP2,MAP3K5,JAK3,NRBP1,RPS6KA3,DRD1,DMPK,RAD21,IRF1,NCKAP5,SUZ12,RPS6KA1,TP53,ETNK1,GMPR,TESK2,ERBB2,NUF2,GRK6,SLC7A2,PRKACA,FLT3,DDR1,ZNF385B,CDK14,KCTD15,ST5,CDH1,SMO,PLK4,CDKN1B,EPHB4,LGMN,LRP11,SCYL3,CPD,MAP3K3,RIPK2,AKT1,PFKFB2,SYNE2,TEP1,PRKCQ,PKMYT1,CBL,TANC1,MAP3K6,EPHA10,IDE,FYN,POPDC3,JAK1,BFSP1,CDK19,PTK7,STK38,AXL,KIAA1804,EFNA5,MLKL,MAMDC2,MAPK12,PINK1,DYRK3,TAOK2,PBX3,TGFBR1,COL4A5,PKN1,TRIB2,ZNF219,CKAP5,IRAK1,ADRBK1,ANKS1B,CDK16,PTEN,SGK3,PLEKHF1,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,MYO5A,PVRL4,PDGFC,CASK,FBLN5,RHOA,LONRF3,ASPM,CXorf57,DIAPH2,LRRC1,YES1,SKA1,TXK,DDAH1,MAMDC4,SEC14L4,ACVRL1,SYT7,FGFR2,CENPE,GRAMD1C,OSR1,HIPK3,MELK |
| 6.265e-07 | -14.28 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | 1210 | 236 | 17775 | 2585 |
LTBP1,GAA,TNK1,ACVR1,CRYM,CAMKK1,EPHA4,RET,DHX8,GATA3,UBE2Q1,TEX2,CAMK1D,KIF26A,SLC20A1,DNER,TMC1,GRM5,PLS3,CDKN2C,NKAIN3,PAK6,DAPK2,WEE1,RPS6KA2,NUP210,TGFBR3,MUC4,CTNNB1,CDKL5,DNAH6,SHC3,ANKFN1,IL31RA,PIK3CA,ATRNL1,RGS5,NTN4,CRY2,SLC39A10,STK35,CCDC74A,PLK1,NEK4,MCTP1,MARK1,ACVR1C,ASXL1,PBK,ROR1,AURKB,LDB2,IDH1,ADRBK2,STK17B,ULK2,KCNK1,PLK2,LIMK1,MYLK,TRAF3IP1,MAP3K11,MAPK13,RNASEL,APBA2,PDPR,GAB1,PRKAA2,CDK17,FRMD4A,PRKAA1,ADCK5,CNTNAP2,SAMD9,MERTK,BMP2K,MECOM,MYO5C,ATG4A,CALR,RB1,CA2,IGF1R,PIK3AP1,GATA2,BDH1,NEK2,DAPK1,PRKCI,PRKG1,ADCK2,MAP3K9,FNIP1,CADPS2,ALPK1,PIM1,CACNA1D,MAPK7,PHKG2,KDELR1,ADCK3,TESK1,STAT4,FHL2,STRADB,VEZT,EIF2AK1,PDK3,PDIK1L,C3orf58,NFIB,EGFR,PDE11A,STK17A,GNAS,MAPKAPK2,CACHD1,NAAA,INSR,MPP2,RAB31,ALPK3,AURKA,CABIN1,CDK18,LTBP2,MAP3K5,JAK3,NRBP1,RPS6KA3,DRD1,DMPK,RAD21,IRF1,NCKAP5,SUZ12,RPS6KA1,TP53,ETNK1,GMPR,TESK2,ERBB2,NUF2,GRK6,SLC7A2,PRKACA,FLT3,DDR1,ZNF385B,CDK14,KCTD15,ST5,CDH1,SMO,PLK4,CDKN1B,EPHB4,LGMN,LRP11,SCYL3,CPD,MAP3K3,RIPK2,AKT1,PFKFB2,SYNE2,TEP1,PRKCQ,PKMYT1,CBL,TANC1,MAP3K6,EPHA10,IDE,FYN,POPDC3,JAK1,BFSP1,CDK19,PTK7,STK38,AXL,KIAA1804,EFNA5,MLKL,MAMDC2,MAPK12,PINK1,DYRK3,TAOK2,PBX3,TGFBR1,COL4A5,PKN1,TRIB2,ZNF219,CKAP5,IRAK1,ADRBK1,ANKS1B,CDK16,PTEN,SGK3,PLEKHF1,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,MYO5A,PVRL4,PDGFC,CASK,FBLN5,RHOA,LONRF3,ASPM,CXorf57,DIAPH2,LRRC1,YES1,SKA1,TXK,DDAH1,MAMDC4,SEC14L4,ACVRL1,SYT7,FGFR2,CENPE,GRAMD1C,OSR1,HIPK3,MELK |
| 6.443e-07 | -14.26 | MODULE_12 | MSigDB lists | MODULE_12 | 353 | 86 | 17758 | 2588 |
MYL9,UGT8,TRIM2,PAX6,HSPG2,S100A11,THRA,GMPR,PLA2G16,CCND1,ZYX,SRPX,LMO4,FOSB,DNM2,BCL6,GOT1,ARNT2,IFIT1,NOTCH3,CPE,HSPA2,CYP1B1,SGCE,MBP,COL6A2,SLC11A2,KLK6,ALCAM,LHFPL2,DPYSL3,GPRC5B,MYLK,WWTR1,TLE1,PIK3C2B,SERPINI1,APBA2,BIN1,WASF3,COL9A3,PCOLCE,CDKN1C,IGFBP6,ENO2,ATP9A,ITGA6,DNAJB2,SOX9,ASAH1,CYB561,SLC1A3,TRIB2,SEPP1,DHRS3,FBLN1,TSPAN7,TMEM63A,SPP1,CYR61,GPC3,COL6A1,ALDH7A1,IGFBP2,ERBB3,NCAM1,DLX4,FADS2,HES1,NR4A1,GRIN1,EMP3,FOS,RHOB,USP6,TIMP3,SLC4A4,ITGA7,DTX4,RAB31,TCEAL4,CDK18,STK39,L1CAM,COL16A1,ARHGEF4 |
| 6.446e-07 | -14.25 | GREENBAUM_E2A_TARGETS_UP | MSigDB lists | GREENBAUM_E2A_TARGETS_UP | 33 | 17 | 17758 | 2588 |
RACGAP1,NUSAP1,KIF2C,CCNB1,ANLN,KIF11,CDKN2C,TOP2A,CCNA2,CA2,FGFR2,PLK4,AURKA,BUB1,SLC12A2,CCNB2,WBP5 |
| 6.500e-07 | -14.25 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 255 | 67 | 17758 | 2588 |
SLC35D2,UGT8,TTC39B,FAM129B,TSC22D3,FAM102B,NDRG2,GRK6,CAMK1D,CA8,CDKN2C,ZFYVE16,SP100,FAM46A,ENPP5,DUSP10,TNFRSF18,CTTN,TMEM64,PXMP4,ARL4D,RAB27B,F2R,S100A13,ANKRD9,MGAT5,ORAI2,RFK,KIAA0040,CDA,PRKCQ,OPTN,TRIM47,ALDH5A1,PTPRJ,VSIG10,GRN,CMAS,PLSCR4,FRMD4A,EPS8,SERPINB9,PBX3,DOCK11,TMCC3,FRY,TMEM62,SGK3,FAM102A,TMEM8A,SLC45A3,ARAP2,PCBP3,EMP3,PYGL,GRTP1,MEST,NCOA3,ACADSB,RCBTB2,FAAH,OTUB2,PGM2L1,FGD6,ZMIZ1,DEF6,RUSC1 |
| 6.567e-07 | -14.24 | GSE2706_UNSTIM_VS_8H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_R848_DC_DN | 186 | 53 | 17758 | 2588 |
DDX58,TXN,ARMCX3,IL15,MACC1,PARP14,SOD2,HERC5,CD274,HERC6,DUSP5,SLC9A7,BTG3,SESN3,ITGB8,GRHL1,OSBPL3,ATP13A3,CD70,IFIT1,TINAGL1,ARL4D,MOXD1,RASGRP1,IGSF3,PARP9,PHLDB3,RAPGEF2,USP18,STAT4,LYRM1,SAT1,PTGER4,DUSP4,IFIT3,SOCS3,DGKH,ARHGAP24,BTG1,CASP7,SWAP70,SHROOM3,TRIM69,NMI,SIPA1L1,STAT1,NLRC5,NR4A3,TDRD7,NFKBIZ,CMPK2,IFIH1,IFI6 |
| 6.567e-07 | -14.24 | GSE3982_BCELL_VS_TH2_DN | MSigDB lists | GSE3982_BCELL_VS_TH2_DN | 186 | 53 | 17758 | 2588 |
ARHGAP11A,MRC2,SPC25,DLGAP5,EPAS1,FOXM1,VANGL1,ATP9A,CIT,CENPI,ATP2C2,PTTG1,GATA3,KIF2C,HES2,HOXB2,NCS1,ZFYVE9,RCN1,BTG3,CYP1A1,BDH1,DAPK1,MAPK11,DIXDC1,ALDH3A2,PSMA5,MSH6,CKS2,HMMR,PLK1,MPP1,SPA17,PYGL,YES1,RAB38,SEC14L2,EDNRA,FECH,SFXN1,GABRD,FYN,FAM64A,BMP1,INPP4B,MAOA,XRCC3,GEM,TBC1D4,LIFR,AFAP1,ACOT7,RPS6KA3 |
| 6.584e-07 | -14.23 | Immune System | REACTOME pathways | R-HSA-168256 | 1371 | 267 | 8202 | 1235 |
TXN,TRIM5,KLC2,TAP1,FBXO2,NRG2,CUL1,IL18,PSME1,PJA2,KIF26A,SPSB1,CALM2,AP1M2,PSMD1,ELMO2,STIM1,PIK3CA,DNM2,IRF2,PIK3CD,ERAP2,CASP9,AGO4,PRKAR2B,RNF19B,PLCG1,LIMK1,MAP3K11,NOD2,MAPK13,RNASEL,GAB1,DDX58,INPPL1,MRC2,NFKBIE,SEC61G,HLA-E,KIF23,CALR,PIK3AP1,CD22,PRKG1,CD70,TNFRSF12A,CTSD,NCAM1,MAPK7,NUP85,KIF20A,MAPKAPK3,MICB,CALM1,CYFIP2,ELK1,PSMA4,RASA1,IL1R1,PELI2,ITPR1,ARPC2,FBXO27,IFIH1,NUP58,RPS6KA3,TMEM173,IRF1,SPRED1,KIF3C,NLRX1,IQGAP1,RPS6KA1,INPP5D,RNF182,CD274,BCL2L1,PRKACA,CD46,RNF220,SP100,CDH1,CDKN1B,DAB2IP,IFIT1,LGMN,RASGEF1A,MX1,SEC23A,SEC61B,RIPK2,PRKCQ,ASB13,ITPR3,CBL,IRS2,FYN,PPP2R5A,JAK1,DDOST,STAT1,NRG1,MAPK12,PRKAR1A,OTUD5,WASF3,TNRC6C,HSP90B1,TRAF2,PDIA3,HERC5,PLD2,FBXO6,FGF19,ICAM1,HLA-A,DTX3L,IRAK1,PTEN,CTSC,KLC3,WWP1,MAPK11,ERBB3,MAP3K7,CNPY3,TRIM62,RASGRF1,RAPGEF2,PIK3R1,GRIN1,UBE2A,YES1,KIF11,FOS,TXK,DCTN6,FGFR2,ERAP1,GRIN2D,FBXO44,CENPE,ITGAV,NUP37,CD81,UNC93B1,SIGIRR,TRIM2,UBE2Q1,UBE2Z,ITPR2,KIF2C,PDGFB,SPTB,TRIM68,SH3KBP1,NUP210,RPS6KA2,CTNNB1,SHC3,IL6ST,PSMC2,TRPC1,DUSP10,TNFRSF18,KIF22,IL1RAP,RASGRP1,NLRP4,CD55,TRIM8,ITCH,USP18,TRIM9,TRIM45,KPNA2,RAP1GAP,PPP2R5D,PSMC1,LGALS3,RASA2,HLA-F,PSMD7,ASB9,CALM3,ATP6V1E2,RACGAP1,NCKAP1,TEC,PHLPP1,DUSP5,UBE2Q2,VASP,PAK2,HLA-C,PSMA5,IFIT3,EGFR,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,NFKBIA,NLRC5,CTSA,PLD1,JAK3,IFI6,PSME2,P2RX7,ERBB2,RASGRP3,PDGFA,ATP6V0B,PLCG2,OAS3,NFKB2,FRS3,MAP3K3,AKT1,TCEB2,CDC20,DUSP4,CD40,CASP4,SOCS3,TAPBP,PTPRJ,STAT6,PSMD3,SPTBN5,IRF7,TAB3,KLHL13,CTSB,PSMD10,SELL,ITGA2B,KIF5B,ADRBK1,UBE2J1,TRIM3,TRIM21,SYK,MYO5A,CAMK2G,DUSP1,ADAM17,PSMB4,IFITM3,NR4A1,TRIM35,PELI3,BCL10,CTSL,HLA-B,CD8A,TRIM69,FGF18,CTSV,UBE2D2,DTX4,ARRB1,ATP6V1C1,ICOSLG,UBE2C,CD33 |
| 6.585e-07 | -14.23 | Lysosome | KEGG pathways | hsa04142 | 123 | 41 | 6908 | 1076 |
LAMP1,GAA,SORT1,CD63,GGA1,CTSB,HEXB,ASAH1,CTSZ,M6PR,GNS,ATP6V0B,ENTPD4,AP1M2,CTSC,ARSG,GALNS,ABCA2,CTSD,LGMN,NAGA,GM2A,LAMP3,LAMP2,NAGPA,GUSB,LITAF,SLC11A2,SLC17A5,NPC2,CTSL,FUCA1,SCARB2,CTNS,GNPTAB,CTSV,PLA2G15,GLB1,CTSA,GLA,ARSB |
| 6.585e-07 | -14.23 | Lysosome | KEGG pathways | ko04142 | 123 | 41 | 6908 | 1076 |
LAMP1,GAA,SORT1,CD63,GGA1,CTSB,HEXB,ASAH1,CTSZ,M6PR,GNS,ATP6V0B,ENTPD4,AP1M2,CTSC,ARSG,GALNS,ABCA2,CTSD,LGMN,NAGA,GM2A,LAMP3,LAMP2,NAGPA,GUSB,LITAF,SLC11A2,SLC17A5,NPC2,CTSL,FUCA1,SCARB2,CTNS,GNPTAB,CTSV,PLA2G15,GLB1,CTSA,GLA,ARSB |
| 6.589e-07 | -14.23 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | 139 | 43 | 17758 | 2588 |
KLF2,LASP1,PCOLCE,TM2D2,PAPSS2,SH3D19,ASAH1,COL4A5,FAM101B,DHRS3,MAP1LC3B,DDR1,EMP2,WWP2,CTGF,LLGL2,IL6ST,CD9,CITED2,SNX10,S100A13,CTDSP2,CRTAP,RBMS2,EPHX1,DUSP1,AMOTL2,SEC61B,PRSS23,SESN1,FOS,TP53INP2,C3orf58,SOCS3,TRIM47,TIMP3,DGCR2,CCDC6,SHROOM3,SLC4A3,FHL1,TMEM159,TOB1 |
| 6.625e-07 | -14.23 | OSMAN_BLADDER_CANCER_UP | MSigDB lists | OSMAN_BLADDER_CANCER_UP | 385 | 92 | 17758 | 2588 |
PLA2G4A,PNISR,SSH1,IL15,TUBB4B,IQGAP1,SLC25A13,KCTD12,TGOLN2,LACTB2,KTN1,CHST2,SDF4,ASPHD2,PCNA,P4HB,SLC44A1,SNX16,FAR1,FGFR1OP2,CYP1B1,ENPP4,RIPK2,AGPS,SNTB2,CBX6,DNAJB14,ADRBK2,ALDH3B1,TAPBP,ZNF641,NFKBIZ,NXT2,KLF2,RECQL,GCLM,GOLIM4,HSP90B1,LGALS3,RASA2,CTSB,MCTP2,PDIA3,TIPRL,H1FX,SSX2IP,SLC25A36,CALR,SNX13,VASP,CTSC,SPIN4,SLC16A6,ALG13,BAX,BRD7,FNIP1,H2AFY,USP1,HSPA13,CTSD,CITED2,TMX1,CRTAP,TRAK2,ACBD5,ALDH2,PLSCR1,LONRF3,LPGAT1,OXR1,PIK3R1,PARP4,FBXO9,DIAPH2,FAM133B,KIAA1109,RUNX3,G2E3,FRMD4B,DCAF10,SCARB2,OTUD6B,SLC25A40,PRPS2,DCUN1D1,ERAP1,TOB1,LRRC57,FBXW5,USP16,RAD21 |
| 6.625e-07 | -14.23 | response to stress | biological process | GO:0006950 | 3601 | 631 | 16441 | 2455 |
ADD1,GRIK2,TRIM5,AK7,DNAJC3,RET,XIAP,FBXO2,SMARCAL1,CCNO,NRG2,IL18,MORF4L2,BARD1,KIF26A,PHF1,TP73,CALM2,WEE1,PHYHIP,PSMD1,TGFBR3,UBE2T,DNM2,CRY2,PPP1CA,PIK3CD,MANF,IL10RB,APOBEC3G,TUBA4A,NEK4,TNIP1,SPRTN,KDELR3,PRKAR2B,LOXL2,F12,RNF19B,MYOM1,ARF4,GINS4,LCP1,PLCG1,LIMK1,MYLK,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,HSPB1,GAB1,NUAK1,SEC61G,ITGA6,RAB23,MERTK,LMNA,ATG4A,ELF3,TFAP4,RAC2,ZCCHC17,RIMS3,FLRT3,FAM13B,MAP3K9,USP1,ALPK1,STT3B,MYDGF,PANX2,NCAM1,MAPK7,ULBP2,DGKG,NDUFA12,NUP85,REC8,UFD1L,MAPKAPK3,ERO1A,SRSF5,ELK1,ILK,GNA11,PSMA4,RHOB,PTPRF,IL1R1,ITPR1,RAET1L,DYSF,MDH1,STK39,ARPC2,CBX5,TRPC3,NUP58,RPS6KA3,TMEM173,EGLN1,DOCK9,NQO1,PAPSS2,TUBB4B,INPP5D,ACTR8,PTTG1,PRKACA,CCND1,SP100,LRP11,RASGEF1A,CDKN2D,RNF169,MX1,ENPP4,SEC61B,RIPK2,APOBEC3D,LGALS8,NRBF2,XRCC6BP1,IRS2,ALDH3B1,WFS1,AXL,RGS14,GEN1,ARNT,MAPK12,TNRC6C,NKX3-1,TAOK2,HSP90B1,TRAF2,CCM2,SDC4,HABP4,FLOT1,PDIA3,PKN1,ETS1,GSTP1,NFAT5,TIPRL,ICAM1,PDIA4,CTNNBIP1,DTX3L,CAPN2,CXCL16,PDCD10,IRAK1,CST3,BAX,ADAM15,TMBIM6,MAPK11,AK3,TMX1,PARP9,PLSCR1,BCL9,RAPGEF2,PIK3R1,NUB1,GRIN1,UBE2A,TXK,BTG1,HCP5,PLOD2,ACVRL1,SYT7,SLC35B3,DBI,NR4A3,OSER1,ITGAV,HMGA1,CENPE,NUP37,WDR45B,MYL9,SIGIRR,UNC93B1,TNK1,EPAS1,CUL4B,LMCD1,DNAJB11,F11R,ITPR2,TP53I11,HDAC6,PDGFB,SDC1,SPTB,FANCI,PCNA,NUP210,RPS6KA2,CTNNB1,SHC3,P4HB,PSMC2,DUSP10,TNFRSF18,SCARA3,PLK1,CD55,KCNIP3,NFE2L1,CR2,ERP44,KLK6,PRKRA,IDH1,SESN1,CDK1,VCP,OPTN,DPYSL3,KDM4D,KCNMB4,WIPI1,KPNA2,MAFF,RRAGD,PRKAA2,LGALS3,DNAJB2,HLA-F,RASA2,PSMD7,RACGAP1,NCKAP1,DOCK11,FBLN1,ANO1,CORO1B,BMP2,TIMP1,GATA2,PAK2,SELK,MDFIC,AHCY,WNT3A,PSMA5,STRADB,SCRIB,EIF2AK1,PDK3,IFIT3,RASGRP2,MAPKAPK2,PHLPP2,CSF1,NLRC5,ATP1B3,PLD1,IFI6,USP43,RAD21,FOXM1,XYLT1,TMX4,DGKA,TP53,ERBB2,P2RX7,RASGRP3,SLC7A2,PER2,IER3,RAD23A,PDGFA,SRPX,PLCG2,BCL6,CDH3,OAS3,SCN2A,LMAN1,EGLN3,CTDSP2,CTH,SIRT1,PPIF,ERLEC1,TCEB2,AKT1,PTGER4,MYL12A,DNAJC10,DUOX1,PTGS2,RTN4RL1,ABHD12,PSMD3,PTK7,XRCC3,IRF7,LTA4H,PINK1,CPEB4,CD63,TAB3,DAP,CTSB,SWI5,SELL,PSMD10,IL22RA1,DNAJB9,SIRPA,FZD6,TFAP2A,UBE2J1,SGK1,TRIM21,HMGCL,SYK,CAMK2G,ATP2B1,DUSP1,P2RX4,RHOA,PSMB4,IFITM3,AMFR,PLAUR,PPARA,TRIM35,FXR2,BCAR1,TXNDC11,MAPK8IP1,DGKE,BCL10,CD83,SERPINA1,SCG2,NEIL3,NMI,FGF18,E2F1,PKD2,ICOSLG,PTGES,ACVR1,TXN,LGR4,TSC22D3,KLC2,TAP1,GATA3,CUL1,PSME1,CAMK1D,CCNB1,VASH1,ELMOD2,CHST2,PICK1,PAK6,CYP1A1,CTGF,STIM1,ELMO2,ZFP36,IL31RA,POLL,AOX1,PIK3CA,IRF2,LAMP2,SPATA18,CASP9,BNIP3L,SLC35C1,AGO4,PIF1,ULK2,AREG,SH2D3C,NFKBIZ,MAPK13,F2RL1,DDX58,KLF2,RECQL,THEMIS2,HLA-E,DGKQ,PRKAA1,KIF23,SLC1A3,TNFRSF19,PSIP1,MECOM,CALR,ITGA3,CYR61,VASN,RPL39,PRKG1,DAPK1,TPST1,MSH2,GFPT1,PRODH,DDB2,MICB,CALM1,ANO6,WHSC1,CYFIP2,RASA1,PDE11A,FAS,DGKH,PELI2,MATN2,NR4A2,MAP3K5,IFIH1,IRF1,EHD1,PLA2G4A,KIF3C,SPRED1,SLC2A4,NLRX1,THRA,RPS6KA1,NDRG1,BCL2L1,SNN,DDR1,APOBEC3B,CD46,NOV,CCNA2,RALB,CDKN1B,DAB2IP,RNASEH2A,IFIT1,LGMN,GPX4,ATG4D,CDKN2AIP,PRKCQ,SLC11A2,RAD17,ATP1B1,ITPR3,AKR1E2,FZD7,FYN,DDOST,JAK1,STK26,KIAA1804,STAT1,SLC27A1,NRG1,ATMIN,PRKAR1A,OTUD5,MRPS9,HERC5,PLD2,APOBEC3H,FBXO6,SEPP1,FGF19,LGALS3BP,HLA-A,FAM111A,E2F7,OXCT1,PTEN,CD9,SGK3,ERCC2,ERBB3,MAP3K7,CITED2,CNPY3,TRIM62,MSH6,RASGRF1,PAPD7,PARP4,FBXO9,C1GALT1C1,YES1,FOS,KIF11,TIMP3,PRDX3,FGFR2,GRIN2D,GPER1,CPEB2,MELK,USP16,CASP3,FAF2,KIF2C,MAP1LC3B,TRIM68,AKR1B1,KIF22,ASH2L,ARNT2,IL1RAP,FGFR1OP2,RASGRP1,CYP1B1,NLRP4,TDP1,SOD1,TRIM8,USP18,ITCH,EDNRA,MDK,NEIL1,ARHGEF19,HPSE,CAB39,PPP2R5D,PSMC1,NR2C2,SERPINE2,ETV5,CALM3,TEC,PHLPP1,DUSP5,SPP1,CA2,KCNN4,FNIP1,BRAT1,HLA-C,HP1BP3,MDFI,ELK3,OXR1,VWA1,HMG20B,PDE5A,EGFR,GNAS,CGREF1,NFKBIA,CDCA5,YOD1,JAK3,APOL2,DRD1,GAS2L1,SLC25A24,PAX6,IL15,PSME2,SLC2A8,PDIA5,SOD2,GMPR,COL18A1,IL27RA,CYP4F11,TWIST1,EPB41L4B,NFKB2,PDIA6,F2R,HSPA2,FRS3,BAG4,MRPS35,DUSP4,CD40,FANCE,MAP3K6,CASP4,SOCS3,JADE1,STAT6,RCAN2,SPTBN5,ABCA1,GCLM,ANXA3,JKAMP,SHPRH,TGFBR1,ITGA2B,HDAC9,TOP2A,IL17RB,ADRBK1,ADORA1,BMP7,ADAM17,WNT10B,NR4A1,GCLC,RGCC,POLD3,ARHGAP24,CTSL,HLA-B,CD8A,PRCP,DHRS2,CTSV,DTX4,UBE2D2,ARRB1,HOXB13,L1CAM |
| 6.648e-07 | -14.22 | testis-germ_cell_tumour-seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-seminoma | 673 | 144 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,CAMK1D,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,NEB,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,PRKAR2B,ROR1,AURKB,IDH1,ADRBK2,STK17B,ABR,ULK2,PLK2,LIMK1,MYLK,MAP3K11,BMP1,MAPK13,RNASEL,PRKAA2,CDK17,DHPS,PRKAA1,ADCK5,MERTK,PDXDC1,BMP2K,IGF1R,NEK2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,KCTD3,PHKG2,ABCC1,ADCK3,TESK1,STRADB,WHSC1,EIF2AK1,PDK3,PDIK1L,RANBP9,EGFR,STK17A,MAPKAPK2,INSR,ALPK3,AURKA,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,TCF25,TRIP10,RPS6KA1,TP53,TESK2,ERBB2,RHPN2,GRK6,PRKACA,DDR1,FLT3,CDK14,SP100,PLK4,EPHB4,SCYL3,MAP3K3,AKT1,RIPK2,PRKCQ,PKMYT1,MAP3K6,EPHA10,DUOX1,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,MAPK12,TAOK2,DYRK3,PINK1,TGFBR1,PKN1,TRIB2,DSE,SNTA1,TMEM87B,ADRBK1,IRAK1,CDK16,TUBGCP6,SGK3,SGK1,H2AFY,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,MYO5A,CASK,ASPM,YES1,TXK,FGFR2,ACVRL1,NEIL3,PRCP,RIN3,WDR91,HIPK3,MELK |
| 6.700e-07 | -14.22 | ovary-carcinoma | COSMIC cancer mutations | ovary-carcinoma | 962 | 194 | 17775 | 2585 |
CCNI,ACACB,TNK1,ACVR1,CAMKK1,EPHA4,RET,MPP5,CAMK1D,ITPR2,PLXNA1,SLC20A1,CDKN2C,PAK6,DAPK2,WEE1,SIPA1L2,RPS6KA2,CTNNB1,CTGF,CDKL5,ELF5,KCNS3,PIK3CA,ASH2L,DDX59,STK35,PLK1,NEK4,MARK1,TNIP1,ACVR1C,PBK,ROR1,GALNT7,AURKB,CCNF,IDH1,ADRBK2,STK17B,ULK2,SFXN1,TMEM164,PLK2,ATP7B,LIMK1,MYLK,MAP3K11,DHTKD1,MAPK13,RNASEL,PRKAA2,CDK17,PRKAA1,ADCK5,MERTK,BMP2K,RB1,UBE2Q2,IGF1R,FRY,SNX18,NEK2,MSH2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,ALPK1,PIM1,MAPK7,MOXD1,ETV7,KANK3,PHKG2,ABCC1,PRSS23,BTNL9,ADCK3,TESK1,PTPRH,STRADB,EIF2AK1,PDK3,PDIK1L,GNA11,EGFR,STK17A,GLCE,GNAS,BCAR3,MAPKAPK2,TSC1,INSR,SEMA4D,APPL2,ALPK3,AURKA,DYSF,CDK18,MAP3K5,JAK3,CDAN1,NRBP1,RPS6KA3,DMPK,FBXW5,PKD1L2,PAX6,SLC2A8,PSME2,RPS6KA1,TP53,TESK2,ERBB2,GRK6,PRKACA,FLT3,DDR1,MNS1,C1orf116,CDK14,ZNF687,CDH1,PLK4,EPHB4,FLOT2,SCYL3,MAP3K3,RIPK2,AKT1,FZD4,FIGNL1,SYNE2,PRKCQ,PKMYT1,ITPR3,TANC1,MAP3K6,EPHA10,FYN,JAK1,CDK19,PTK7,STK38,AXL,KIAA1804,MLKL,MAPK12,PINK1,DYRK3,TAOK2,JRKL,SHPRH,BACE1,CCM2,TGFBR1,PKN1,TRIB2,M6PR,ADD3,ADRBK1,IRAK1,CDK16,FAM160A2,PTEN,SGK3,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,TGIF1,ADAM17,CASK,ASPM,PIK3R1,YES1,FOS,TXK,LDLRAP1,FAT4,ACVRL1,FGFR2,ABCB1,CCDC69,UACA,ARRB1,HIPK3,MELK,GOLGB1 |
| 6.701e-07 | -14.22 | Signaling by PDGF | REACTOME pathways | R-HSA-186797 | 345 | 86 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,COL6A2,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,STAT6,PSMD3,STAT1,MAP3K11,NRG1,SPTBN5,PSMC1,GAB1,PPP2R5D,PRKAR1A,COL9A3,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,COL4A5,PHLPP1,FGF19,DUSP5,ITGA2B,SPP1,ADRBK1,PTEN,COL6A1,ERBB3,NCAM1,PSMA5,CAMK2G,DUSP1,RASGRF1,PDGFC,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,FURIN,BCAR1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 6.754e-07 | -14.21 | REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR | MSigDB lists | REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR | 121 | 39 | 17758 | 2588 |
NFKBIE,PSME2,PSMD7,PSMD10,CALM3,CUL1,RASGRP3,PSME1,ITPR2,PHLPP1,SH3KBP1,CALM2,PSMD1,PTEN,PIK3AP1,STIM1,PLCG2,PSMC2,CDKN1B,PIK3CD,MAP3K7,SYK,RASGRP1,PSMA5,AKT1,PSMB4,NR4A1,PIK3R1,CALM1,CASP9,CBL,ITPR3,PSMA4,BCL10,PLCG1,FYN,PSMD3,NFKBIA,PSMC1 |
| 6.785e-07 | -14.20 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN | 191 | 54 | 17758 | 2588 |
TXN,DLGAP5,NQO1,FOXM1,PTTG1,ERCC6L,CDCA3,CDCA8,KIF2C,EGR3,CCNB1,STIL,FANCI,SAC3D1,CKAP5,TOP2A,RB1,PCNA,BDH1,TUBG1,CKS1B,BUB1,LGMN,FAH,LAMP3,GCNT1,CKS2,HMMR,ZWINT,CENPA,MLEC,HN1L,KIF20A,ASPM,PBK,CDC20,ACO1,NUSAP1,GGH,SLC25A5,KIF11,ADRBK2,DHX32,IL1R1,NEIL3,CORO1C,AURKA,CENPE,GLA,CCNB2,UBE2C,ESPL1,ACOT7,CPPED1 |
| 6.785e-07 | -14.20 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | 191 | 54 | 17758 | 2588 |
CD99,SLC35D2,ACVR1,LGALS3,S100A11,TUBB4B,IQGAP1,CD82,EPHA4,PTTG1,GATA3,CBLL1,DUSP5,CORO1B,CAPN2,WEE1,TGFBR3,TIMP1,OSBPL3,PRC1,DUSP10,TAGLN2,TMEM64,FAR2,PDIA6,MYBL1,SNX10,MYO5A,ATP2B1,CASK,TNIP1,S100A4,SYNE2,EZR,DIAPH2,RNF19B,ALCAM,FAS,OPTN,ARHGAP35,ENDOD1,SLC6A6,AMMECR1,LRIG1,RAB11FIP1,NOD2,GLB1,CTSA,PIEZO1,MAP3K5,TTC39C,AHR,FAM45A,GOLGB1 |
| 6.978e-07 | -14.18 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN | 196 | 55 | 17758 | 2588 |
GRN,LGALS3,CD63,NDRG1,BLVRB,APOO,CTSZ,F11R,BCAP31,LMNA,SGPL1,ARHGEF10L,APLP2,SPP1,TNS3,RPS6KA2,CAPG,CD9,DAPK1,CNNM4,STEAP3,NPTN,CTTN,PTPRE,S100A13,SYK,LAMP2,SOAT1,GCA,ALDH2,MPP1,HSPA12A,VAMP3,CDA,HMG20B,TCF7,NPC2,SAV1,IDH1,POR,PLEKHB1,GABARAPL1,HLA-B,LDLRAP1,INSR,PRCP,SLC2A6,RAB31,CLIP4,ZDHHC7,DYSF,CD81,SLC27A3,RRAGD,CD33 |
| 6.978e-07 | -14.18 | GSE7460_TCONV_VS_TREG_THYMUS_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_UP | 196 | 55 | 17758 | 2588 |
EXPH5,DDX58,MFSD3,FBLIM1,ANKRD13D,ARHGEF11,ELOVL7,ARL4C,FAM78A,ZNRF3,TMEM170B,GRK6,SLC20A1,FAM101B,KREMEN1,FZD6,TMEM63A,OTUD1,CEP97,ZCCHC12,TACC2,ZFP36,CYP2S1,MITF,FAM102A,SGK1,TINAGL1,CNGA1,TRAM1,MYLIP,SLC16A5,CTDSP2,HP1BP3,P2RX4,QSOX1,TIMP2,SLC35C1,FBXO9,ARHGDIB,NPC2,NEURL1B,TANC1,ELK1,XKRX,KCNMB4,GPRC5B,RCBTB2,ACVRL1,P4HA2,SLC9A6,C1orf21,RAP2C,APOL2,ZBTB33,CXorf56 |
| 7.134e-07 | -14.15 | RIGGI_EWING_SARCOMA_PROGENITOR_UP | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_UP | 407 | 96 | 17758 | 2588 |
ACACB,NCKAP5,KIAA1462,GRIK2,EPHA4,LMCD1,IL13RA1,CD274,CDK14,CDS1,PDGFA,ZCCHC12,LMO4,PAQR5,PLCG2,REEP1,STEAP2,STEAP3,RGS5,TMEM37,F2R,ODF2L,IL1RAP,PCGF5,LGALS8,FZD4,SLC39A8,PTGER4,ARHGDIB,LDB2,EDNRA,KDSR,PGF,HS6ST1,ENPP1,PTGS2,ATP1A1,ALDH5A1,JAK1,ZNF704,NR3C2,MAMDC2,RRAGD,FBLIM1,FARP1,RBM24,KLHL13,POC1B,HLA-E,SERPINB9,EFHD2,GDF15,ISYNA1,JAG2,TRIB2,DUSP5,PARM1,ICAM1,ZDHHC21,HDAC9,SPP1,GATA2,FLRT3,BHLHE41,TOX2,OPN3,DAPK1,IGFBP2,CADPS2,TSPAN13,ALDH7A1,FAM84B,CITED2,IGSF3,IGDCC4,CYP26B1,HES1,STAT4,CRIP2,PIK3R1,SPATA13,KBTBD8,STMN3,TRIM35,FOS,STEAP1,GLCE,GALNT3,CACHD1,FAT4,FGF18,PGM2L1,MAP3K5,JAK3,TMEM173,JARID2 |
| 7.230e-07 | -14.14 | DITTMER_PTHLH_TARGETS_UP | MSigDB lists | DITTMER_PTHLH_TARGETS_UP | 108 | 36 | 17758 | 2588 |
LAMP1,LTBP1,CDCA3,FLOT1,DUSP5,SGPL1,CTNNB1,COL6A1,DLG1,USP1,KLF9,NPTN,ATP2B1,GPX4,CKS2,CPD,PDGFC,PRSS23,TNIP1,GALNT7,POLD3,ATP10D,RANBP9,CDK1,ARF4,RHEB,NUCB1,TIMP3,ATP1A1,H1F0,AREG,STK39,B4GALT3,F2RL1,UBE2C,ANXA11 |
| 7.288e-07 | -14.13 | positive regulation of protein serine/threonine kinase activity | biological process | GO:0071902 | 290 | 75 | 16441 | 2455 |
CCNC,AVPI1,IQGAP1,EPHA4,P2RX7,ERBB2,CCNL1,PDGFB,FLT3,STIL,ERP29,CARD10,GRM5,TP73,CALM2,CCND1,PDGFA,RALB,DAB2IP,HSPA2,RASGRP1,DVL2,SIRT1,SOD1,PSRC1,RIPK2,AKT1,FZD4,CD40,CDK1,MAP3K6,MADD,KIAA1804,NOD2,MAP3K11,CAB39,SLC27A1,GAB1,TAB3,TRAF2,PRKAA1,PSMD10,CALM3,PKN1,DUSP5,BMP2,PDCD10,IRAK1,MAP3K9,MDFIC,MAPK11,PIM1,MAP3K7,IQGAP3,SYK,SPRY2,MDFI,ADAM17,MAPKAPK3,RAPGEF2,CALM1,RGCC,PDE5A,ILK,EGFR,CDK5R1,MAPKAPK2,INSR,FGF18,ARRB1,PKD2,EFNA1,FZD5,MAP3K5,CD81 |
| 7.354e-07 | -14.12 | CYTOPLASMIC_PART | MSigDB lists | CYTOPLASMIC_PART | 1354 | 260 | 17758 | 2588 |
LAMP1,MRPS15,AASS,SLC25A13,KLC2,XIAP,TGOLN2,CNTROB,OAT,CHST2,PICK1,SLC9A7,NPM2,NAPG,STIM1,RGS3,ZFP36,RDH14,STEAP2,FUT1,TUBG1,TACSTD2,ERAP2,LAMP2,SGCE,SNTB2,UXT,BNIP3L,CDA,TMEM98,SLC17A5,ICMT,MYOM1,POR,LCP1,SLC25A4,DNM1L,ATP7B,MAP3K11,NOD2,SERPINB6,MRPS28,ARF6,F2RL1,FGD1,GGA1,SLC25A27,NDUFA4,APBA1,ATG4A,CALR,DOPEY2,WDFY1,NECAB3,NEK2,STT3B,EEF1D,TMED2,PIGC,QSOX1,KIF20A,KIF20B,NPC2,CYFIP2,STX3,AP1AR,HTT,ARAP1,FGD6,MDH1,NDE1,PLIN3,EGLN1,SLC2A4,DLGAP5,BCL2L1,AIFM2,KTN1,RCN1,CDH1,PHKA2,GPX4,ATG4D,SEMA3B,SEC23A,SEC61B,TMEM43,AGPS,COG2,VPS4B,COX11,KIF1C,PKMYT1,ITPR3,NIN,GABARAPL1,FYN,STX10,DDOST,SLC9A6,ISOC1,HSP90B1,BACE1,PDIA3,CTSZ,NUCB2,PDIA4,CKAP5,OXCT1,FUT2,ARSG,CTSC,FDXR,TUBGCP6,BAX,TMBIM6,ECI2,AK3,ITM2C,SGCB,TMX1,PCCB,SHMT1,PIK3R1,FURIN,RAB3IP,SNTB1,CRISPLD2,NUCB1,LDLRAP1,CTNS,KIAA0141,ACADSB,PRDX3,PLOD2,ARFGAP3,ERAP1,ARSB,ESPL1,MYL9,DNAJB11,ITPR2,ERP29,MAP1LC3B,DNER,SPTB,ARHGEF10L,ENTPD4,TM9SF2,CTNNB1,P4HB,CNTRL,ARL1,LMAN2L,ABCA2,TMEM143,CTTN,PXMP4,TRAM1,NEB,LAMP3,PLK1,PCGF5,SOD1,EZR,ARHGDIB,ERP44,MRPS18A,ANLN,IDH1,MRPS36,VCP,OPTN,AGPAT2,WIPI1,DOLPP1,GLA,POMT1,RAP1GAP,PCSK5,LASP1,PEX6,RAB6A,PGAP1,CES2,PFKL,OCRL,PRKCI,MPHOSPH9,CCDC88A,KDELR1,RGMB,PDK3,CDK5R1,EGFR,GLCE,GNAS,TSC1,CTSA,PLD1,SHROOM2,IFI6,NF2,IL15,SOD2,PDIA5,TP53,EXT2,SYTL2,RPN2,LMAN1,MINPP1,PDIA6,F2R,SCYL3,SOAT1,CLCN3,ACO1,MRPS35,TMTC2,TAPBP,ALDH5A1,IDE,PEX2,SECTM1,SYT13,ANXA9,AIFM3,ABCA1,PINK1,GOLIM4,CD63,SERPINB9,DSE,AIP,VPS26A,DNAJB9,SAC3D1,KIF5B,TOP2A,MAGEE1,RRBP1,SLC35B4,BUB1,SLC35A1,RPGR,B3GALT6,NR3C1,AMFR,PRICKLE1,USP6,BCL10,TMEM50B,CASP7,PKD2,ACADM,PLOD3,CEP41,GOLGB1,ABCG1 |
| 7.405e-07 | -14.12 | Rho guanyl-nucleotide exchange factor activity | molecular function | GO:0005089 | 77 | 29 | 16491 | 2452 |
PLEKHG3,RASGRF1,ARHGEF28,ARHGEF3,FARP1,ARHGEF11,ARHGEF7,SPATA13,DOCK11,ARHGEF40,ARHGEF16,EPS8L2,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,MCF2L,PLEKHG1,FGD6,TIAM1,ALS2CL,ARHGEF9,NGEF,FARP2,DOCK9,ARHGEF4,FGD1 |
| 7.590e-07 | -14.09 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | 221 | 60 | 17758 | 2588 |
ILDR1,AVPI1,TUBB4B,KLHL13,TMEM41B,COL4A5,F11R,FBXO6,TRIB2,FAM101B,SIRPA,LMNA,TOP2A,VASP,LYPD3,VASN,RRBP1,NEK2,CD9,KLC3,RP2,CTTN,IQGAP3,LOXL1,PTPRE,ITM2C,OSGIN1,TSPAN33,GPX4,PIGC,HES1,PRSS23,GUSB,CDC20,C3orf52,IGSF8,C15orf39,ITPR3,ALCAM,MAPK8IP1,BCL10,RPL12,PAFAH1B3,SHROOM3,RND3,DCK,LIMK1,CORO1C,CDCA5,FAM3C,SECTM1,FAM110C,RELL1,EPB41L4A,ARF6,PLIN3,NRGN,PSMC1,RARG,SNX30 |
| 7.621e-07 | -14.09 | regulation of cell differentiation | biological process | GO:0045595 | 1454 | 282 | 16441 | 2455 |
ACVR1,SSH1,RET,GATA3,IL18,MORF4L2,PLXNA1,CAMK1D,FAM101B,LTBP3,GRM5,NCS1,TP73,CTGF,DNM2,TACSTD2,SEMA3G,PACSIN1,TIAM1,LOXL2,SAV1,POR,ULK2,ENPP1,AREG,PLK2,LIMK1,TBX1,HDAC1,ITPKA,ARF6,LZTS1,SEMA6B,SOX9,FAM21C,MECOM,CALR,ITGA3,CYR61,MEGF8,BHLHE41,VASN,FBXO7,SORL1,TNFRSF12A,RIMS2,SOCS5,EPB41L5,MMD,MFI2,KIF20B,NPHP3,ILK,GNA11,FAS,PTPRF,AP1AR,NCOA3,SEMA4D,SETD3,PIAS2,AURKA,EFNA1,GDF11,ARPC2,MAP3K5,RPS6KA3,XDH,EHD1,DMPK,IRF1,FOXO6,GRHL2,THRA,INPP5D,RPS6KA1,SUZ12,PKP2,EGR3,PRKACA,FLT3,APC2,TNFSF9,CCND1,CD46,NOV,DACT1,TNPO2,DAB2IP,FLOT2,SEMA3B,SSH3,RIPK2,DMTN,FZD7,FYN,CORO1C,AXL,WWTR1,SIPA1L1,INPP4B,TRIOBP,STAT1,KLF5,RAB29,NRG1,RGS14,ARNT,COBL,MAPK12,CTHRC1,RBM24,FLOT1,ETS1,TEAD3,SIX4,NEO1,CTNNBIP1,PTEN,KNDC1,BAX,MAPK11,RAG1,GFI1,ITM2C,TTPA,SPRY2,TRIM62,TGIF1,TCFL5,RAPGEF2,PIK3R1,GRIN1,FOS,CDK5RAP1,BTG1,PROM1,FGFR2,NR1D2,ACVRL1,ITGAV,GPER1,OSR1,ARSB,SHOX2,FOXA1,EMX1,EPHA4,HDAC6,CTNNB1,CDKL5,NPNT,DPYSL2,IL6ST,ELF5,MITF,DUSP10,CTTN,RASGRP1,SOD1,ASXL1,KLK6,CDK1,PLEKHB1,RHEB,DPYSL3,IRX3,GPRC5B,HOXA9,MAFF,GRN,RUNX2,PPP1R12A,LGALS3,SERPINE2,UBASH3B,ETV5,FBLN1,BMP2,RB1,SPP1,CA2,GATA2,FAM20C,KIF13B,PRKCI,SUCO,FNIP1,NPTN,C10orf54,WNT3A,NTN1,CCDC88A,HMG20B,PDE5A,KIAA1109,CDK5R1,SOX13,GNAS,TMEM30A,CSF1,NFKBIA,FAM213A,JAK3,SEMA3A,RARG,TOB1,GAS2L1,PAX6,NF2,IL15,TP53,ERBB2,EMP2,PER2,KIF14,LMO4,SMO,BCL6,TWIST1,DIXDC1,TMEM64,NOTCH3,SIRT1,TIMP2,AKT1,CDC20,DAG1,SOCS3,ARHGAP35,HSF4,PTGS2,BHLHB9,PTK7,IRF7,EFNA5,PLXND1,ABCA1,CTDSP1,BIN1,SORT1,ADGRG1,ARHGEF7,CIT,LRP4,GDF15,TGFBR1,CRABP2,TRIB2,HDAC9,CD109,MYCL,BMP7,KIAA0319,TFAP2A,H2AFY,SYK,TLE6,FAM134C,HES1,RHOA,WNT10B,ASPM,RGCC,MBNL3,PPARA,PRICKLE1,RUNX3,CD83,MAP1B,CNOT2,HLA-B,FAT4,TWSG1,FGF18,E2F1,PPP2R3C,SOX8,NDFIP1,L1CAM,ABCG1,NGEF |
| 7.778e-07 | -14.07 | ISHIDA_E2F_TARGETS | MSigDB lists | ISHIDA_E2F_TARGETS | 51 | 22 | 17758 | 2588 |
CDC20,PTTG1,NDC80,NUSAP1,AURKB,CCNB1,ANLN,CDK1,LBR,PRIM1,CDKN2C,TOP2A,RB1,CCNA2,PCNA,UBE2T,PRC1,BUB1,KPNA2,SGOL1,CCNB2,E2F8 |
| 7.877e-07 | -14.05 | epidermal growth factor receptor signaling pathway | biological process | GO:0007173 | 321 | 81 | 16441 | 2455 |
SPRED1,REPS2,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,SH3KBP1,PDGFA,CALM2,PSMD1,SHC3,PSMC2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,PRKAR2B,AGO4,ERBB2IP,CBL,ITPR3,ARF4,IRS2,PLCG1,FYN,JAK1,AREG,PSMD3,SPTBN5,NRG1,GAB1,PSMC1,PRKAR1A,TNRC6C,RASA2,ARHGEF7,EPS8,SOX9,PSMD7,PSMD10,CALM3,PHLPP1,FGF19,DUSP5,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,SOCS5,RASGRF1,ADAM17,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,BCAR1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,FGF18,ITPR1,GRIN2D,JAK3 |
| 8.097e-07 | -14.03 | SASAKI_ADULT_T_CELL_LEUKEMIA | MSigDB lists | SASAKI_ADULT_T_CELL_LEUKEMIA | 168 | 49 | 17758 | 2588 |
CD99,RECQL,DLGAP5,FOXM1,ATP8A1,PTTG1,SELL,KIF2C,CCNB1,TRIB2,ETS1,BARD1,FZD6,PARM1,TOP2A,PCNA,CCNA2,PDCD10,KCNN4,KIF14,TFAP2A,ARNT2,PPP1CA,DLG3,PLK1,SGCE,SMARCA2,ING1,ZWINT,FHL2,ATP1B1,ICMT,IDH1,KIF11,RASA1,FAS,PRDX4,PTPRJ,ACYP1,GDE1,NMI,WWTR1,STAT1,HDAC1,GLB1,PLD1,UBE2C,CCNB2,JAK3 |
| 8.119e-07 | -14.02 | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP | 192 | 54 | 17758 | 2588 |
CMAS,TXN,DLGAP5,LGALS3,GNPDA1,CRYM,DAP,NDUFA4,RACGAP1,ISYNA1,NANS,DPP8,COX6C,MNS1,AIP,REPS1,LGALS3BP,TOP2A,CDKN2C,RAC2,PRC1,CKS1B,KIF22,TAGLN2,AK3,IQGAP3,SGCB,PSMA5,PQLC3,USP18,CDC20,HTATIP2,TNFAIP8L1,GGH,ARHGDIB,NUSAP1,PRRC1,KIF11,CDC25C,CDK1,CASP7,SLC25A4,DDOST,NAT1,CORO1C,CDCA5,DBI,PPP2R4,SSNA1,CCNB2,PSMC1,E2F8,ACOT7,XDH |
| 8.188e-07 | -14.02 | purine nucleoside binding | molecular function | GO:0001883 | 1798 | 338 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,KIF13A,PIF1,AURKB,RAB2B,ARF4,ULK2,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,TRANK1,RALB,FICD,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,GALK1,HSP90B1,TAOK2,ATP9A,ARL4C,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,OPLAH,PCCB,CASK,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PAPSS1,PSMC2,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,PSMC1,RRAGD,PRKAA2,LMTK3,RUNX2,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ABCC1,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,DYRK3,PINK1,TOR4A,CIT,SHPRH,GNAL,GNE,ERCC6L,TGFBR1,KIF5B,TOP2A,ADRBK1,ADORA1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,MYO5A,ATP2B1,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,RAP2C,UBE2D2,GEM,UBE2C,HIPK3,ABCG1 |
| 8.211e-07 | -14.01 | Developmental Biology | REACTOME pathways | R-HSA-1266738 | 710 | 153 | 8202 | 1235 |
MYL9,CCNC,AGRN,EPAS1,EPHA4,NRG2,LGI3,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,PAK6,HELZ2,PSMD1,RPS6KA2,CTNNB1,SHC3,DPYSL2,PSMC2,DLG1,DNM2,DUSP10,TRPC1,NTN4,MYH14,TIAM1,RASGRP1,ACVR1C,EZR,DPYSL3,PLCG1,LIMK1,MAP3K11,UNC5B,PSMC1,MYL12B,PPP2R5D,SCN5A,RASA2,PSMD7,CALM3,DUSP5,RAC2,VASP,PAK2,COL6A1,CACNA1D,NCAM1,NTN1,PSMA5,DPYSL5,RGMB,SALL4,CALM1,EPHA1,DPYSL4,PSMA4,RANBP9,RHOB,EGFR,CDK5R1,RASA1,ONECUT1,NCOA3,SEMA4D,PITPNA,EFNA1,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,SPRED1,SLC2A4,PAX6,PSME2,IQGAP1,RPS6KA1,ERBB2,RASGRP3,PDGFA,ARTN,DAB2IP,EPHB4,SCN2A,RASGEF1A,DLG3,MED30,SCN3A,FRS3,COL6A2,AKT1,DRAP1,PRKCQ,DUSP4,ALCAM,MYL12A,ARHGAP35,EPHA10,IRS2,FYN,PPP2R5A,JAK1,CDK19,PSMD3,KLF5,SPTBN5,NRG1,EFNA5,PLXND1,MAPK12,COL9A3,ARHGEF11,ARHGEF7,PSMD10,COL4A5,EFNB1,FGF19,NRP2,ITGA2B,RND1,NEO1,ANK1,MAPK11,ERBB3,NCOA2,CAMK2G,MED22,FARP2,DUSP1,RASGRF1,HES1,RHOA,ARHGEF28,PSMB4,WNT10B,RAPGEF2,PPARA,FURIN,GRIN1,YES1,ABLIM2,CNTNAP1,FGFR2,FGF18,ARRB1,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 8.318e-07 | -14.00 | HALLMARK_UV_RESPONSE_UP | MSigDB lists | HALLMARK_UV_RESPONSE_UP | 154 | 46 | 17758 | 2588 |
CASP3,ENO2,PPP1R2,CDKN1C,HLA-F,RET,TAP1,SOD2,SPR,PRKACA,ICAM1,BMP2,EPCAM,BTG3,CYP1A1,CA2,MGAT1,IL6ST,FOSB,TMBIM6,IGFBP2,HSPA13,NPTXR,HSPA2,RASGRP1,EPHX1,TUBA4A,PPIF,NR4A1,FURIN,GGH,FOS,CLCN2,RHOB,ONECUT1,BTG1,SLC25A4,PDLIM3,NAT1,NFKBIA,FGF18,ABCB1,MAOA,ATP6V1C1,SHOX2,IRF1 |
| 8.326e-07 | -14.00 | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN | 197 | 55 | 17758 | 2588 |
BIN1,ARHGEF3,ATP9A,TRAF2,SERPINB9,ARL4C,MERTK,FAM46C,TNFSF9,ART5,NCS1,LMNA,M6PR,SPP1,NPNT,ARL1,CAPG,TRIM3,TACSTD2,NFKB2,TIPARP,TGIF1,TNIP1,USP18,STAT4,PIK3R1,LITAF,PLEKHA7,PTGER4,FNDC3A,CLCN2,RNF19B,POR,STX3,ULK2,VCP,EBF2,ARF4,CD83,GABARAPL1,RGS9,SLC6A6,FYN,PEX5,TWSG1,NFKBIA,NR4A3,NR4A2,SERPINI1,MDH1,ITGAV,CMPK2,USF2,TMEM131,EHD1 |
| 8.347e-07 | -14.00 | regulation of cellular component movement | biological process | GO:0051270 | 737 | 158 | 16441 | 2455 |
LAMP1,ACVR1,ATP8A1,RET,GATA3,PLXNA1,CAMK1D,VASH1,HDAC6,PDGFB,EPCAM,DAPK2,TGFBR3,TNFRSF18,TACSTD2,SEMA3G,PIK3CD,CYP1B1,ACVR1C,ARHGDIB,ABR,DPYSL3,PLCG1,MYLK,NKD1,FAM110C,NOD2,HSPB1,F2RL1,GAB1,MIIP,DDX58,SEMA6B,SCN5A,ARAP3,SERPINE2,LGALS3,SOX9,FBLN1,LMNA,SSX2IP,CORO1B,BMP2,CALR,RAC2,ITGA3,TIMP1,IGF1R,CYR61,MEGF8,SORL1,NTN1,WNT3A,EPB41L5,ANO6,SPATA13,KIF20B,EPHA1,ILK,RHOB,EGFR,AP1AR,ONECUT1,INSR,SEMA4D,PLPP3,CSF1,ARAP1,EGFL7,EFNA1,PLD1,CFAP20,SEMA3A,DRD1,NF2,PKP2,COL18A1,CD274,EMP2,PDGFA,SVBP,NOV,SP100,KIF14,BCL6,CDKN1B,DAB2IP,TWIST1,EPB41L4B,PDE4D,F2R,SEMA3B,DOCK4,BAG4,AKT1,PTPRU,DMTN,CCSAP,SYNE2,PTGER4,DOCK5,DAG1,IRS2,PTGS2,ATP1A1,PTPRJ,CORO1C,NRG1,PLXND1,ARHGAP4,TCAF1,ANXA3,ADGRG1,ARHGEF7,SDC4,SELL,CBLL1,TGFBR1,PLD2,JAG2,PKN1,ETS1,SRPX2,ICAM1,PPP2R3A,NRP2,ITGA2B,HDAC9,SNTA1,CXCL16,PDCD10,ADORA1,PTEN,SGK3,SGK1,ADAM15,CITED2,SUN2,RHOA,ADAM17,MPP1,RAPGEF2,PIK3R1,RGCC,FURIN,BBS2,BCAR1,GPLD1,SWAP70,ACVRL1,PRCP,SPINT2,RAP2C,FGF18,ITGAV,GPER1,ARSB,CD81 |
| 8.445e-07 | -13.98 | LEI_MYB_TARGETS | MSigDB lists | LEI_MYB_TARGETS | 308 | 77 | 17758 | 2588 |
MYL9,NF2,TSC22D3,PTTG1,GATA3,BLCAP,SLC20A1,MAP1LC3B,DDR1,PCBP1,EMP2,KTN1,CCND1,EPCAM,PCNA,CDH1,ANKRD12,TUBG1,GM2A,TUBA4A,CKS2,CYP1B1,SMARCA2,TNIP1,ACBD3,SAT1,TFAP2C,AURKB,ITPR3,MYL12A,POR,MDK,PLK2,STAT6,AXL,MAOA,PDXK,ARF6,LTA4H,HSPB1,GRN,ANXA3,LASP1,SERPINE2,FLOT1,PSMD7,ASAH1,PSMD10,CRABP2,GSTP1,DHRS3,LGALS3BP,PFKL,TFAP2A,ACTA2,KLF9,CTSD,EEF1D,PCCB,FADS2,PRSS23,CTNNAL1,MICB,CRIP2,FHL2,LITAF,PSMA4,RASA1,MMP15,MAGED2,BTG1,TIMP3,DHRS2,SETD3,SERPINB5,AURKA,UBE2C |
| 8.461e-07 | -13.98 | MEISSNER_NPC_HCP_WITH_H3K4ME2 | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3K4ME2 | 479 | 109 | 17758 | 2588 |
DOC2A,SLC2A4,S100A11,GRIK2,GALNT12,TSC22D3,SLC25A13,FHDC1,GATA3,PKP2,COL18A1,IL13RA1,NENF,MGAT5B,AIFM2,EMP2,SLC9A3R2,CARD10,DAPK2,EPCAM,KCTD15,N4BP3,ALDH1A3,SLC44A1,ZDHHC23,ABCA2,ESPN,PACSIN1,PTPRE,IL10RB,RASGRP1,SMAGP,MYO5B,CAMSAP3,MBP,SERTAD4,CYS1,LOXL2,ITPR3,ADRBK2,COL12A1,EBF2,ABR,PGF,POPDC3,RCAN2,MLKL,PRIMA1,SYT13,ITPKA,RAP1GAP,SLC27A3,BTBD6,TC2N,COL9A3,ANKRD13D,NKX3-1,PARP12,CDKN1C,ATP9A,CALB2,GNAL,CYB561,PLD2,PM20D2,C11orf95,ADAMTSL4,PRRG4,FZD6,RAVER2,SNTA1,C16orf74,ANK1,PIK3AP1,LLGL2,TMEM62,GPC3,BMP7,FCHO1,IL17RA,ARVCF,TAGLN2,CASD1,DLX4,NFE2L3,SLC37A1,LPGAT1,VWA1,TCF7,PLS1,GRTP1,DPYSL4,MAPK8IP1,FA2H,H1F0,SEMA4D,MFSD2A,NMI,SLC2A6,FGF18,SPINT2,SLC4A3,DYSF,GRIN2D,HMGA1,LRRK1,CCNB2,COL16A1,TLL2 |
| 8.482e-07 | -13.98 | Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | REACTOME pathways | R-HSA-983695 | 36 | 18 | 8202 | 1235 |
CALM1,PIK3R1,CALM3,ITPR2,ITPR3,CBL,SH3KBP1,CALM2,PLCG1,FYN,STIM1,PIK3AP1,CD22,ITPR1,PLCG2,TRPC1,PIK3CD,SYK |
| 8.487e-07 | -13.98 | transferase activity | molecular function | GO:0016740 | 2220 | 407 | 16491 | 2452 |
ACVR1,TRIM24,AK7,TRIM5,RET,HEXB,FBXO2,XIAP,CUL1,PDGFRL,NANS,CAMK1D,OAT,CCNB1,PJA2,BARD1,CHST2,DAPK2,PAK6,WEE1,TYMP,TGFBR3,UBE2T,PIK3CA,POLL,FUT1,PIK3CD,MARCH2,TIPARP,SMYD5,MGAT5,NEK4,TMEM68,FBXL16,ACVR1C,PBK,CDYL,RNF11,AURKB,GALNT7,ICMT,RNF19B,ULK2,PRIM1,PIAS3,GNPTAB,LIMK1,PLK2,MYLK,MAP3K11,PRDM5,MAPK13,RNASEL,WBSCR27,ITPKA,TRAF5,DLAT,CDK17,NUAK1,DHPS,PRKAA1,DGKQ,SOX9,ZNRF3,HERC6,MERTK,BMP2K,RABGGTA,MARCH8,ZNRF2,FBXO7,TPST1,DAPK1,NEK2,MAP3K9,FBXL14,PRKG1,ADCK2,ALPK1,STT3B,PIKFYVE,MAPK7,DGKG,MYLIP,MAST4,PHKG2,PIGC,GFPT1,B3GNT7,DDB2,MMD,MAPKAPK3,ADCK3,LPGAT1,PIP4K2C,WHSC1,PYGL,EPHA1,PKM,ILK,SPTLC2,GLT8D2,FBXO10,STK17A,DGKH,NT5C2,NCOA3,FNTA,PRKAG2,MTFMT,DCK,CSNK1G1,TEX30,SETD3,ZDHHC20,MPP2,DGAT2,PIAS2,AURKA,STK39,CDK18,SAMD8,B4GAT1,ALG2,MAP3K5,NRBP1,RPS6KA3,DMPK,PAPSS2,LFNG,GALNT12,SUZ12,RPS6KA1,ETNK1,TESK2,RNF182,MAPK4,GRK6,MGST2,PRKACA,DDR1,FLT3,ART5,CDS1,CCND1,RNF220,XYLT2,FICD,EPHB4,DLG3,PHKA2,SULT2B1,RIPK2,PFKFB2,AGPS,SAT1,PANK1,TEP1,PRKCQ,PKMYT1,XRCC6BP1,B3GALNT2,CBL,PRDM11,EPHA10,FYN,DDOST,JAK1,STK26,CDK19,AXL,KIAA1804,HS3ST3B1,MLKL,PDXK,B4GALT3,AREL1,SLC27A3,MAPK12,GALK1,TAOK2,GCAT,PARP14,TRAF2,CBLL1,HERC5,FBXO6,PKN1,GSTP1,TSPAN17,WWP2,DTX3L,IRAK1,FUT2,OXCT1,RNF128,MGAT1,MGAT4A,ALG13,FUT8,FAM20B,SGK3,MAPK11,WWP1,ERBB3,ERCC2,AK3,MAP3K7,RAG1,TRIM62,NCOA2,PARP9,B3GNT2,SHMT1,CASK,PAPD7,MPP1,ELOVL3,PARP4,UBE2A,FBXO9,AK4,C1GALT1C1,YES1,PIM3,TXK,GALNT3,CDK5RAP1,FGFR2,ACVRL1,PLA2G15,RYK,PGM2L1,LRRK1,CMPK2,MELK,OCLN,CCNC,LTBP1,TNK1,NMRK1,UGT8,TRIM2,CPT2,CAMKK1,CUL4B,EPHA4,UBE2Q1,UBE2Z,MGAT5B,TAF6L,CDIPT,TRIM68,CHPF,RPS6KA2,CDKL5,METTL7A,PAPSS1,PASK,DLG1,ASH2L,STK35,CERS2,PLK1,MARK1,ITCH,RNF165,CCBL2,ROR1,STK17B,CDK1,ADRBK2,SEC14L2,TRIM9,PI4K2B,HS6ST1,FASTKD1,AGPAT2,PIK3C2B,POMT1,CHPT1,HS6ST3,PRKAA2,LMTK3,PARP12,ELOVL7,ADCK5,TEC,B4GALT4,B4GALNT1,B3GALNT1,TYW3,UBE2Q2,IGF1R,FAM20C,PFKL,CMTR2,PAK2,PRKCI,NPTN,PIM1,CHSY3,TESK1,MGAT4B,GYLTL1B,STRADB,KBTBD8,EIF2AK1,PDK3,PDIK1L,ZDHHC3,CDK5R1,G2E3,EGFR,NMT2,MAPKAPK2,INSR,UAP1,KBTBD2,PAPD5,PRPS2,ALPK3,ZDHHC7,JAK3,RNF146,LMO7,PAX6,UGP2,XYLT1,DGKA,ERBB2,KBTBD11,EXT2,CDK14,SAP130,SETDB2,KMT5C,ZDHHC12,ZDHHC23,PLK4,GYS1,GOT1,RPN2,OAS3,SCYL3,SEPHS1,SOAT1,SIRT1,MAP3K3,TAF5,RFK,AKT1,MAP3K6,PDHX,PAFAH1B3,PTK7,STK38,PEX2,ST3GAL1,POMGNT2,NDST3,CBX4,KDELC2,CMAS,PINK1,CDS2,DYRK3,KLHL13,CIT,SHPRH,GNE,TGFBR1,CHAC2,TRMT2B,POMGNT1,TRIB2,NRP2,ZDHHC21,ADRBK1,CDK16,A4GALT,ZDHHC13,UBE2J1,TRIM3,SGK1,TRIM21,BUB1,SYK,CAMK2G,GCNT1,B3GALT6,AMFR,RC3H2,NADK2,POLD3,DGKE,KLHL2,TRIM69,NAT1,TADA2B,UBE2D2,CSGALNACT1,ARRB1,PLOD3,UBE2C,SAT2,HIPK3 |
| 8.563e-07 | -13.97 | glycoprotein metabolic process | biological process | GO:0009100 | 447 | 105 | 16441 | 2455 |
AGRN,HSPG2,GALNT12,XYLT1,HEXB,FBXO2,NANS,MGAT5B,SDC1,PHLDA1,ART5,EXT2,CHPF,MUC16,MUC4,XYLT2,IMPAD1,FUT1,RPN2,LMAN1,TFG,TIPARP,MGAT5,SULF2,SIRT1,SEC23A,TNIP1,ERP44,PXYLP1,SLC17A5,GALNT7,B3GALNT2,MCFD2,ARF4,VCP,MAN2A2,HS6ST1,HPSE,DDOST,AREG,DOLPP1,GNPTAB,CANT1,HS3ST3B1,B4GALT3,POMT1,ST3GAL1,NDST3,POMGNT2,HS6ST3,CMAS,TRAPPC10,MAN1A2,GNE,SDC4,PDIA3,CTSZ,FBXO6,B4GALT4,DSE,POMGNT1,ADAMTSL4,B4GALNT1,CALR,BMP2,B3GALNT1,FUT2,CTSC,MGAT1,A4GALT,MGAT4A,ALG13,GPC3,FUT8,UBE2J1,STT3B,SLC35A1,PPP6R1,TMED2,GCNT1,TRAK2,CHSY3,GFPT1,B3GALT6,NAGPA,B3GNT7,MLEC,B3GNT2,MGAT4B,GYLTL1B,PARP4,C1GALT1C1,COL7A1,FOXL1,GLCE,GALNT3,FUCA1,UAP1,SERPINA1,CSGALNACT1,GLB1,CTSA,ALG2,B4GAT1,ARSB |
| 8.619e-07 | -13.96 | nucleoside binding | molecular function | GO:0001882 | 1805 | 339 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,CDA,KIF13A,PIF1,AURKB,RAB2B,ARF4,ULK2,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,TRANK1,RALB,FICD,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,GALK1,HSP90B1,TAOK2,ATP9A,ARL4C,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,OPLAH,PCCB,CASK,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PSMC2,PAPSS1,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,PSMC1,RRAGD,PRKAA2,LMTK3,RUNX2,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ABCC1,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,DYRK3,PINK1,TOR4A,SHPRH,CIT,GNAL,GNE,ERCC6L,TGFBR1,KIF5B,TOP2A,ADRBK1,ADORA1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,MYO5A,ATP2B1,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,RAP2C,UBE2D2,GEM,UBE2C,HIPK3,ABCG1 |
| 8.634e-07 | -13.96 | intestinal_adenocarcinoma | COSMIC cancer mutations | intestinal_adenocarcinoma | 7530 | 1207 | 17775 | 2585 |
HECA,IBTK,GRIK2,RET,TRAPPC8,BAIAP3,DPP8,LTBP3,ZNF275,GRM5,NPM2,NAPG,MUC4,UBE2T,ATP13A3,CRY2,RNF26,WBP4,TIAM1,TIPARP,MGAT5,DNAAF3,NEK4,CDA,ABR,ARF4,PLCG1,CARHSP1,MPRIP,ATP7B,NOD2,RNASEL,STARD13,SCN5A,GGA1,ITGA6,FAM21C,TTYH3,ATG4A,MARCH8,FLII,RAC2,SH3D21,FRY,MEGF8,FLRT3,FBXO7,PCYOX1,MAP3K9,SLAIN2,USP38,CNGA1,MAPK7,ZMYM1,DGKG,NUP85,HPS3,KIF20B,NPHP3,DPYSL4,PCTP,SFXN5,GNA11,CACHD1,FNTA,SLC4A4,ETS2,S100A5,CLMN,GDF11,TMEM173,DOCK9,TPRN,RHBDL3,GRK6,FAM91A1,MOCS1,APPBP2,RCN1,RBM23,MUC16,ST5,CDH1,XYLT2,ENPP5,RASGEF1A,DLG3,MX1,SNX8,SEC61B,ERMP1,RIPK2,PFKFB2,AGPS,SAT1,SYP,TANC1,ZNF618,TRIM7,COX20,EBF2,GIGYF1,CCNB3,WFS1,AXL,PNPLA6,FAM149A,SLC25A30,ISOC1,CTHRC1,MPZL1,FAM189A2,CKAP2,ESRP1,TRAF2,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,NFAT5,SLC25A45,PDCD10,IGSF9,MGAT4A,CST3,TUBGCP6,FAM20B,BAX,ZFAND4,FAM102A,RAG1,CASD1,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,PGBD1,CNTNAP1,PROM1,PLOD2,PLA2G15,PPM1H,ITGAV,OSR1,PHC1,TMEM131,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,TEX2,MGAT5B,ITPR2,SPTB,CPNE2,RPS6KA2,NUP210,CTNNB1,P4HB,TMEM143,ABCA2,PLK1,THRB,CELSR2,STAU2,NFE2L1,CR2,CKAP2L,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,TRAM2,KLF12,HOXA9,KPNA2,HS6ST3,RUNX2,HJURP,RASA2,SORBS3,NCKAP1,ANO1,MYO5C,B4GALNT1,TNS3,RINL,FRAS1,ICAM5,FCHO1,SLC30A6,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,SCRIB,PDK3,PRX,NMT2,RASGRP2,COL13A1,KBTBD2,PHLPP2,SLC2A6,ZDBF2,SEMA3A,CDAN1,USP43,CTDSPL,TP53,STIL,SYTL2,TTC21B,TACC2,PLK4,CDH3,VAT1,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,AKT1,SERTAD3,ACO1,C3orf33,ATP13A2,TAPBP,ZNF628,PTPRJ,RBL1,STK38,MMP17,MAOA,ST3GAL1,ZMAT1,BIN1,CMAS,DYRK3,CDH22,TAB3,KLHL13,GNAL,ERCC6L,GTF3A,NRP2,FZD6,CD109,FOXP2,CDK16,IL17RA,HMGCL,SYK,ATP2B1,GCNT1,NFE2L3,HES1,RHOA,HMGN5,GUSB,PLAUR,CRIP2,STMN3,DPP9,MAML2,COL7A1,RNPEP,DGKE,BCL10,DDX23,NEIL3,E2F1,SH3BGRL2,HIPK3,GOLGB1,LAMP1,SLC35D2,PNISR,HSPG2,TSC22D3,PDGFRL,VASH1,PJA2,SLC9A7,PAK6,CYP1A1,ZNF823,STIM1,OSBPL3,FOSB,PIK3CA,IRF2,SGCE,CDYL,SLC35C1,KIF13A,LDB2,POR,SH2D3C,LRIG1,PRDM5,BMP1,SERPINI1,SPRY4,WBSCR27,FGD1,SEMA6B,RECQL,MRC2,CDKN1C,APBA1,TNFRSF19,SH3RF2,DOPEY2,MSH2,DAPK1,TMEM51,PRKG1,CACNA1D,DLX4,SYTL3,ZNF117,GPR161,GCC2,PRODH,LPGAT1,DCHS1,WHSC1,ATP8B3,ANTXR1,PDE11A,NT5C2,AP1AR,SLCO4A1,TJP3,FAAH,PELI2,MATN2,MPP2,APPL2,ARAP1,AGBL5,SFMBT1,ZBTB34,PLIN3,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,REPS2,CAPN12,CCDC110,NDRG1,CERCAM,ATP2C2,FAM78A,TMEM19,FLT3,DDR1,ZFYVE9,EPS8L2,EPM2A,C11orf84,CD46,ACAP2,TRANK1,EPHB4,RNASEH2A,PDE4D,OSBPL7,FLOT2,SULT2B1,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,CLSTN1,UTRN,KIF1C,TMEM144,PKMYT1,CBL,ITPR3,TRIQK,ATP10D,FZD7,ZMPSTE24,CCDC149,TRIOBP,SLC27A3,COBL,MAMDC2,HAPLN3,CENPI,CBLL1,HERC5,NES,PLD2,DNAH3,HLA-A,CKAP5,SLC25A36,RASSF8,RNF128,FUT8,CD9,ERBB3,TTPA,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ARHGEF28,ZC3H11A,PAPD7,TMEM221,ZKSCAN2,GRTP1,ARSK,KIF11,DGCR2,SEC14L4,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR91,FZD5,WDR62,ESPL1,RGMA,VARS2,MPP5,COMMD5,ERP29,ECI1,ZFYVE16,SIPA1L2,CDKL5,ANKFN1,CEP78,ASH2L,CTTN,MYRIP,IL1RAP,TRAPPC13,CXXC5,ASXL1,LAP3,USP18,RGAG1,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SP6,RBM43,CAPN1,PCSK5,ARAP3,PPP1R12A,SERPINE2,BVES,PYROXD2,FAM81A,ADAMTSL4,QSOX2,SPP1,B3GALNT1,CES2,PFKL,FAM20C,OCRL,COL6A1,PRKCI,LIMCH1,C10orf54,NPTN,HLA-C,SLC12A2,SNED1,ELK3,PODXL2,KIAA1109,HEATR5A,PDIK1L,RANBP9,RHPN1,SOX13,INSR,DONSON,SHROOM2,JAK3,COL16A1,SNX30,DRD1,CCNE2,LMO7,NCKAP5,LZTFL1,PAX6,SOD2,COL18A1,MRAS,OSR2,EXT2,KCTD9,SAP130,ZNF687,CYP4F11,ZBTB49,ECE1,UPF3A,SEPHS1,PTPRU,MRPS35,TMTC2,CDC25C,PDHX,SOCS3,ARHGAP35,HSF4,STAT6,TLE1,RCAN2,SPTBN5,ABCA1,KDELC2,FBLIM1,TSPAN15,ARHGEF7,SH3D19,SHPRH,TGFBR1,INTS8,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,TOX2,RRBP1,ACTA2,ARVCF,KANK2,CLIP2,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,FAM73B,TCEAL8,LEPR,LEMD2,ARHGAP24,SWAP70,FIBCD1,CSGALNACT1,DTX4,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,ABCG1,CD33,ACACB,IL15RA,ADD1,TRIM5,AASS,MRPS15,XIAP,CACNA2D2,FAM102B,DHX8,LGI3,KIF26A,BARD1,DAPK2,ZYX,TGFBR3,RGS12,ARHGAP42,KIAA1107,DNAH6,CYP2S1,KLF3,ALDH1A3,SEMA3G,PIK3CD,TINAGL1,APOBEC3G,ODF2L,NWD1,SMARCA2,TNIP1,LOXL2,MYOM1,CYP4F3,COL12A1,SLC44A3,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,RELL1,PDPR,GAB1,FAM169A,ALDH6A1,NFKBIE,TMTC3,CYP2J2,SOX9,STRN4,SLC36A4,ZNRF3,LMNA,ELF3,RAVER2,FAM189A1,CD22,NEK2,NCAM1,SLC37A1,KIF20A,STAT4,CALCRL,PLS1,MEST,SPTLC2,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SEMA4D,HTT,ITPR1,DYSF,AURKA,FBXO27,ZNF502,TRPC3,RPS6KA3,MTM1,PAPSS2,GALNT12,WDTC1,PKP2,IL13RA1,NUF2,PRSS22,APC2,ZNF385B,UHRF1BP1L,SCNN1A,RNF220,SP100,DACT1,RTKN2,SCN3A,RNF169,SSH3,CAMSAP3,PSRC1,SYNE2,IRS2,PEX5,TTC12,SLC9A6,WWTR1,SIPA1L1,INPP4B,PLEKHG1,ARNT,TTC8,TAOK2,TNRC6C,FARP1,RBM24,PARP14,MAN1A2,GMCL1,ANO9,PKN1,PDIA4,NEO1,CAPN2,ANK1,ADD3,SLC27A6,FAM160A2,CTSC,ANKS1B,CALD1,PLEKHF1,ADAM15,ZNF230,WWP1,AK3,SGCB,CRTAP,HCN3,POU6F1,AMOTL2,FMN1,FAM160A1,CTNNAL1,RAPGEF2,DBR1,MYEOV,FAM109A,SNTB1,CRISPLD2,ABLIM2,PITX2,ACVRL1,ARFGAP3,CENPE,AGRN,PPM1J,EPHA4,MCCC1,NDC80,CDIPT,PDGFB,SHC3,MKRN3,ELF5,DUSP10,RGS5,TLN2,PXMP4,ANO4,MYBL1,NEB,CCDC38,ZNF462,CD55,C12orf65,EZR,TNFAIP8L1,KLK6,ESYT1,IDH1,LHFPL2,CLCN2,VCP,IRX3,OPTN,PLCH1,MFAP3L,TBC1D17,MAP2,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,POMT1,GLCCI1,PRKAA2,ZCCHC24,HLA-F,RACGAP1,CNTNAP2,B4GALT4,DOCK11,SSX2IP,CORO1B,RB1,DAZAP1,KIAA0895,IGF1R,EXOC8,MDFIC,TMEM8A,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,G2E3,MOSPD3,ITGA7,LTBP2,CTBP1,RNF146,KCNAB3,NF2,UGP2,UPF3B,FOXM1,DGKA,ERBB2,SLC7A2,CCNL1,FAM198B,LPIN3,CYP26A1,SDF4,PER2,CDK14,SCN2A,TMTC1,MBP,FIGNL1,CDC20,MYPOP,DUOX1,RTN4RL1,ATP1A1,PTK7,ADAMTS14,RPL22,ZNF701,ZC3HC1,MAN2B2,COL9A3,GOLIM4,TRAPPC10,MACC1,RUSC2,GNE,PSMD10,SELL,NKRF,JAG2,DSE,PPP2R3A,SLC9A2,GBX2,CCDC92,CEP97,MAGEE1,SLC35B4,BUB1,IGDCC4,DLGAP1,HMMR,TRIM35,FXR2,FNDC3A,BCAR1,BSDC1,SCRN2,CD83,FAT4,SERPINA1,TMC5,CDCA7L,CLIP4,PPP2R3C,PKD2,DIS3L,SUN1,GAA,ACVR1,PPP4R4,TTC39B,TMEM41B,FAM129B,ATP8A1,KLC2,PPFIBP2,GATA3,PLXNA1,CHST2,NCS1,SESN3,ELMO2,PRICKLE3,IQCE,IL31RA,STEAP2,AOX1,ATRNL1,MTMR11,PACSIN1,ORAI2,LOC81691,TMEM68,HSPA12A,TNS1,GALNT7,SLC17A5,CCNF,SLC25A5,ZFAND5,TP53I3,ARHGEF26,AHRR,SFXN1,KDSR,RBM47,PLK2,GNPTAB,NKD1,UNC5B,TANC2,TRAF5,RTN3,LZTS1,DLAT,CDK17,INPPL1,FRMD4A,DGKQ,C6orf106,ISYNA1,NOTCH2,BMP2K,KIAA1161,MECOM,SNX18,OPN3,CTPS1,SORL1,PIKFYVE,CTSD,RIMS2,IGSF3,EPB41L5,QSOX1,DDB2,MFI2,TBC1D8B,AMER1,ANO6,VEZT,FAM133B,KDM3A,FBXO10,STX3,RASA1,GABRD,SERTAD2,ISM1,SLC4A3,PCDH19,NR4A2,MAP3K5,PKD1L2,IRF1,FRMPD3,SLC2A4,ARMCX3,NLRX1,SUZ12,IQGAP1,RPS6KA1,IRX4,CD274,EGR3,MNS1,SLC25A35,APLP2,ZNF75D,TNPO2,CNNM4,DAB2IP,PHKA2,LGMN,NR2C1,CAPN6,TEP1,PRKCQ,BCL7B,C15orf39,ZNF469,PRDM11,NIN,EPHA10,ZNF641,FYN,JAK1,PPP2R5A,KIAA1804,STAT1,KLF5,NRG1,HS3ST3B1,MLKL,NR3C2,ATMIN,DENND5B,WASF3,SLC16A14,ATP9A,CCNJL,CYB561,PNPLA5,TEAD3,LGALS3BP,AKIRIN1,PHF7,OXCT1,PTEN,MGAT1,PRC1,SGK3,CNOT6L,SPRY2,OSGIN1,NCOA2,SMC4,RASGRF1,ARAP2,MPP1,FURIN,PARP4,LRRC1,GPLD1,MAMDC4,RCBTB2,PRDX3,SLC25A40,CSTF2,PGM2L1,GRIN2D,ETAA1,NCAPG2,ARSB,JARID2,EXPH5,LTBP1,CASP3,CPT2,EPHX4,UBE2Z,KIF2C,DNER,CACNB4,KREMEN1,DENND2D,TMC1,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,LRRC6,GRHL1,ANKRD12,AKR1B1,KIF22,RAB20,MYH14,ARNT2,SLC39A10,PTPRE,OLFML2A,SOD1,SYNE3,RNF165,ROR1,ADRBK2,EDNRA,ARHGEF19,IARS2,LEMD1,PSMC1,PPP2R5D,LRRFIP2,PEX6,ASL,SAMD9,ZNF432,OTUD1,AIM1L,LRRN2,KCNN4,FNIP1,ZNF692,RFX5,KNTC1,SIMC1,LRIF1,ALS2CL,HP1BP3,PARD3B,OXR1,GYLTL1B,HMG20B,RNF113A,EGFR,GLCE,GNAS,XKRX,BCAR3,ONECUT1,TSC1,SLC6A6,UTP14C,RHOBTB2,ALPK3,KIF12,KLF7,FBXW5,PROM2,GAS2L1,SLC25A24,SLC2A8,ABCG4,TDRKH,MICALL2,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,KHNYN,FRYL,SMO,APIP,FRS3,BAG4,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,CANT1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,FRMD6,LRP4,FAM134A,MIER3,NOTUM,POMGNT1,FAM167A,ZNF212,SNX13,ADORA1,MLPH,GALNS,KIAA0319,BRD7,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,PHLDB3,OGDHL,POLD3,SPAG1,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,L1CAM,LRRC57 |
| 8.634e-07 | -13.96 | stomach-carcinoma-intestinal_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-intestinal_adenocarcinoma | 7530 | 1207 | 17775 | 2585 |
HECA,IBTK,GRIK2,RET,TRAPPC8,BAIAP3,DPP8,LTBP3,ZNF275,GRM5,NPM2,NAPG,MUC4,UBE2T,ATP13A3,CRY2,RNF26,WBP4,TIAM1,TIPARP,MGAT5,DNAAF3,NEK4,CDA,ABR,ARF4,PLCG1,CARHSP1,MPRIP,ATP7B,NOD2,RNASEL,STARD13,SCN5A,GGA1,ITGA6,FAM21C,TTYH3,ATG4A,MARCH8,FLII,RAC2,SH3D21,FRY,MEGF8,FLRT3,FBXO7,PCYOX1,MAP3K9,SLAIN2,USP38,CNGA1,MAPK7,ZMYM1,DGKG,NUP85,HPS3,KIF20B,NPHP3,DPYSL4,PCTP,SFXN5,GNA11,CACHD1,FNTA,SLC4A4,ETS2,S100A5,CLMN,GDF11,TMEM173,DOCK9,TPRN,RHBDL3,GRK6,FAM91A1,MOCS1,APPBP2,RCN1,RBM23,MUC16,ST5,CDH1,XYLT2,ENPP5,RASGEF1A,DLG3,MX1,SNX8,SEC61B,ERMP1,RIPK2,PFKFB2,AGPS,SAT1,SYP,TANC1,ZNF618,TRIM7,COX20,EBF2,GIGYF1,CCNB3,WFS1,AXL,PNPLA6,FAM149A,SLC25A30,ISOC1,CTHRC1,MPZL1,FAM189A2,CKAP2,ESRP1,TRAF2,HABP4,OSGIN2,BTN3A1,CTSZ,PLPPR4,NFAT5,SLC25A45,PDCD10,IGSF9,MGAT4A,CST3,TUBGCP6,FAM20B,BAX,ZFAND4,FAM102A,RAG1,CASD1,PARP9,ACBD5,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,NUB1,MRS2,CXorf57,PGBD1,CNTNAP1,PROM1,PLOD2,PLA2G15,PPM1H,ITGAV,OSR1,PHC1,TMEM131,ILDR1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,TEX2,MGAT5B,ITPR2,SPTB,CPNE2,RPS6KA2,NUP210,CTNNB1,P4HB,TMEM143,ABCA2,PLK1,THRB,CELSR2,STAU2,NFE2L1,CR2,CKAP2L,DZIP1L,KDM4D,TRIM9,PLEKHG6,TMEM164,HS6ST1,TRAM2,KLF12,HOXA9,KPNA2,HS6ST3,RUNX2,HJURP,RASA2,SORBS3,NCKAP1,ANO1,MYO5C,B4GALNT1,TNS3,RINL,FRAS1,ICAM5,FCHO1,SLC30A6,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,SCRIB,PDK3,PRX,NMT2,RASGRP2,COL13A1,KBTBD2,PHLPP2,SLC2A6,ZDBF2,SEMA3A,CDAN1,USP43,CTDSPL,TP53,STIL,SYTL2,TTC21B,TACC2,PLK4,CDH3,VAT1,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,AKT1,SERTAD3,ACO1,C3orf33,ATP13A2,TAPBP,ZNF628,PTPRJ,RBL1,STK38,MMP17,MAOA,ST3GAL1,ZMAT1,BIN1,CMAS,DYRK3,CDH22,TAB3,KLHL13,GNAL,ERCC6L,GTF3A,NRP2,FZD6,CD109,FOXP2,CDK16,IL17RA,HMGCL,SYK,ATP2B1,GCNT1,NFE2L3,HES1,RHOA,HMGN5,GUSB,PLAUR,CRIP2,STMN3,DPP9,MAML2,COL7A1,RNPEP,DGKE,BCL10,DDX23,NEIL3,E2F1,SH3BGRL2,HIPK3,GOLGB1,LAMP1,SLC35D2,PNISR,HSPG2,TSC22D3,PDGFRL,VASH1,PJA2,SLC9A7,PAK6,CYP1A1,ZNF823,STIM1,OSBPL3,FOSB,PIK3CA,IRF2,SGCE,CDYL,SLC35C1,KIF13A,LDB2,POR,SH2D3C,LRIG1,PRDM5,BMP1,SERPINI1,SPRY4,WBSCR27,FGD1,SEMA6B,RECQL,MRC2,CDKN1C,APBA1,TNFRSF19,SH3RF2,DOPEY2,MSH2,DAPK1,TMEM51,PRKG1,CACNA1D,DLX4,SYTL3,ZNF117,GPR161,GCC2,PRODH,LPGAT1,DCHS1,WHSC1,ATP8B3,ANTXR1,PDE11A,NT5C2,AP1AR,SLCO4A1,TJP3,FAAH,PELI2,MATN2,MPP2,APPL2,ARAP1,AGBL5,SFMBT1,ZBTB34,PLIN3,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,REPS2,CAPN12,CCDC110,NDRG1,CERCAM,ATP2C2,FAM78A,TMEM19,FLT3,DDR1,ZFYVE9,EPS8L2,EPM2A,C11orf84,CD46,ACAP2,TRANK1,EPHB4,RNASEH2A,PDE4D,OSBPL7,FLOT2,SULT2B1,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,CLSTN1,UTRN,KIF1C,TMEM144,PKMYT1,CBL,ITPR3,TRIQK,ATP10D,FZD7,ZMPSTE24,CCDC149,TRIOBP,SLC27A3,COBL,MAMDC2,HAPLN3,CENPI,CBLL1,HERC5,NES,PLD2,DNAH3,HLA-A,CKAP5,SLC25A36,RASSF8,RNF128,FUT8,CD9,ERBB3,TTPA,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ARHGEF28,ZC3H11A,PAPD7,TMEM221,ZKSCAN2,GRTP1,ARSK,KIF11,DGCR2,SEC14L4,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR91,FZD5,WDR62,ESPL1,RGMA,VARS2,MPP5,COMMD5,ERP29,ECI1,ZFYVE16,SIPA1L2,CDKL5,ANKFN1,CEP78,ASH2L,CTTN,MYRIP,IL1RAP,TRAPPC13,CXXC5,ASXL1,LAP3,USP18,RGAG1,ARHGDIB,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SP6,RBM43,CAPN1,PCSK5,ARAP3,PPP1R12A,SERPINE2,BVES,PYROXD2,FAM81A,ADAMTSL4,QSOX2,SPP1,B3GALNT1,CES2,PFKL,FAM20C,OCRL,COL6A1,PRKCI,LIMCH1,C10orf54,NPTN,HLA-C,SLC12A2,SNED1,ELK3,PODXL2,KIAA1109,HEATR5A,PDIK1L,RANBP9,RHPN1,SOX13,INSR,DONSON,SHROOM2,JAK3,COL16A1,SNX30,DRD1,CCNE2,LMO7,NCKAP5,LZTFL1,PAX6,SOD2,COL18A1,MRAS,OSR2,EXT2,KCTD9,SAP130,ZNF687,CYP4F11,ZBTB49,ECE1,UPF3A,SEPHS1,PTPRU,MRPS35,TMTC2,CDC25C,PDHX,SOCS3,ARHGAP35,HSF4,STAT6,TLE1,RCAN2,SPTBN5,ABCA1,KDELC2,FBLIM1,TSPAN15,ARHGEF7,SH3D19,SHPRH,TGFBR1,INTS8,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,LLGL2,TOX2,RRBP1,ACTA2,ARVCF,KANK2,CLIP2,MYO5A,PGM1,PHF20L1,SYBU,RC3H2,TTC7A,RUNX3,FAM73B,TCEAL8,LEPR,LEMD2,ARHGAP24,SWAP70,FIBCD1,CSGALNACT1,DTX4,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,ABCG1,CD33,ACACB,IL15RA,ADD1,TRIM5,AASS,MRPS15,XIAP,CACNA2D2,FAM102B,DHX8,LGI3,KIF26A,BARD1,DAPK2,ZYX,TGFBR3,RGS12,ARHGAP42,KIAA1107,DNAH6,CYP2S1,KLF3,ALDH1A3,SEMA3G,PIK3CD,TINAGL1,APOBEC3G,ODF2L,NWD1,SMARCA2,TNIP1,LOXL2,MYOM1,CYP4F3,COL12A1,SLC44A3,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,RELL1,PDPR,GAB1,FAM169A,ALDH6A1,NFKBIE,TMTC3,CYP2J2,SOX9,STRN4,SLC36A4,ZNRF3,LMNA,ELF3,RAVER2,FAM189A1,CD22,NEK2,NCAM1,SLC37A1,KIF20A,STAT4,CALCRL,PLS1,MEST,SPTLC2,DHX32,STK17A,PTPRF,NCOA3,SCARB2,SEMA4D,HTT,ITPR1,DYSF,AURKA,FBXO27,ZNF502,TRPC3,RPS6KA3,MTM1,PAPSS2,GALNT12,WDTC1,PKP2,IL13RA1,NUF2,PRSS22,APC2,ZNF385B,UHRF1BP1L,SCNN1A,RNF220,SP100,DACT1,RTKN2,SCN3A,RNF169,SSH3,CAMSAP3,PSRC1,SYNE2,IRS2,PEX5,TTC12,SLC9A6,WWTR1,SIPA1L1,INPP4B,PLEKHG1,ARNT,TTC8,TAOK2,TNRC6C,FARP1,RBM24,PARP14,MAN1A2,GMCL1,ANO9,PKN1,PDIA4,NEO1,CAPN2,ANK1,ADD3,SLC27A6,FAM160A2,CTSC,ANKS1B,CALD1,PLEKHF1,ADAM15,ZNF230,WWP1,AK3,SGCB,CRTAP,HCN3,POU6F1,AMOTL2,FMN1,FAM160A1,CTNNAL1,RAPGEF2,DBR1,MYEOV,FAM109A,SNTB1,CRISPLD2,ABLIM2,PITX2,ACVRL1,ARFGAP3,CENPE,AGRN,PPM1J,EPHA4,MCCC1,NDC80,CDIPT,PDGFB,SHC3,MKRN3,ELF5,DUSP10,RGS5,TLN2,PXMP4,ANO4,MYBL1,NEB,CCDC38,ZNF462,CD55,C12orf65,EZR,TNFAIP8L1,KLK6,ESYT1,IDH1,LHFPL2,CLCN2,VCP,IRX3,OPTN,PLCH1,MFAP3L,TBC1D17,MAP2,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,POMT1,GLCCI1,PRKAA2,ZCCHC24,HLA-F,RACGAP1,CNTNAP2,B4GALT4,DOCK11,SSX2IP,CORO1B,RB1,DAZAP1,KIAA0895,IGF1R,EXOC8,MDFIC,TMEM8A,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,G2E3,MOSPD3,ITGA7,LTBP2,CTBP1,RNF146,KCNAB3,NF2,UGP2,UPF3B,FOXM1,DGKA,ERBB2,SLC7A2,CCNL1,FAM198B,LPIN3,CYP26A1,SDF4,PER2,CDK14,SCN2A,TMTC1,MBP,FIGNL1,CDC20,MYPOP,DUOX1,RTN4RL1,ATP1A1,PTK7,ADAMTS14,RPL22,ZNF701,ZC3HC1,MAN2B2,COL9A3,GOLIM4,TRAPPC10,MACC1,RUSC2,GNE,PSMD10,SELL,NKRF,JAG2,DSE,PPP2R3A,SLC9A2,GBX2,CCDC92,CEP97,MAGEE1,SLC35B4,BUB1,IGDCC4,DLGAP1,HMMR,TRIM35,FXR2,FNDC3A,BCAR1,BSDC1,SCRN2,CD83,FAT4,SERPINA1,TMC5,CDCA7L,CLIP4,PPP2R3C,PKD2,DIS3L,SUN1,GAA,ACVR1,PPP4R4,TTC39B,TMEM41B,FAM129B,ATP8A1,KLC2,PPFIBP2,GATA3,PLXNA1,CHST2,NCS1,SESN3,ELMO2,PRICKLE3,IQCE,IL31RA,STEAP2,AOX1,ATRNL1,MTMR11,PACSIN1,ORAI2,LOC81691,TMEM68,HSPA12A,TNS1,GALNT7,SLC17A5,CCNF,SLC25A5,ZFAND5,TP53I3,ARHGEF26,AHRR,SFXN1,KDSR,RBM47,PLK2,GNPTAB,NKD1,UNC5B,TANC2,TRAF5,RTN3,LZTS1,DLAT,CDK17,INPPL1,FRMD4A,DGKQ,C6orf106,ISYNA1,NOTCH2,BMP2K,KIAA1161,MECOM,SNX18,OPN3,CTPS1,SORL1,PIKFYVE,CTSD,RIMS2,IGSF3,EPB41L5,QSOX1,DDB2,MFI2,TBC1D8B,AMER1,ANO6,VEZT,FAM133B,KDM3A,FBXO10,STX3,RASA1,GABRD,SERTAD2,ISM1,SLC4A3,PCDH19,NR4A2,MAP3K5,PKD1L2,IRF1,FRMPD3,SLC2A4,ARMCX3,NLRX1,SUZ12,IQGAP1,RPS6KA1,IRX4,CD274,EGR3,MNS1,SLC25A35,APLP2,ZNF75D,TNPO2,CNNM4,DAB2IP,PHKA2,LGMN,NR2C1,CAPN6,TEP1,PRKCQ,BCL7B,C15orf39,ZNF469,PRDM11,NIN,EPHA10,ZNF641,FYN,JAK1,PPP2R5A,KIAA1804,STAT1,KLF5,NRG1,HS3ST3B1,MLKL,NR3C2,ATMIN,DENND5B,WASF3,SLC16A14,ATP9A,CCNJL,CYB561,PNPLA5,TEAD3,LGALS3BP,AKIRIN1,PHF7,OXCT1,PTEN,MGAT1,PRC1,SGK3,CNOT6L,SPRY2,OSGIN1,NCOA2,SMC4,RASGRF1,ARAP2,MPP1,FURIN,PARP4,LRRC1,GPLD1,MAMDC4,RCBTB2,PRDX3,SLC25A40,CSTF2,PGM2L1,GRIN2D,ETAA1,NCAPG2,ARSB,JARID2,EXPH5,LTBP1,CASP3,CPT2,EPHX4,UBE2Z,KIF2C,DNER,CACNB4,KREMEN1,DENND2D,TMC1,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,LRRC6,GRHL1,ANKRD12,AKR1B1,KIF22,RAB20,MYH14,ARNT2,SLC39A10,PTPRE,OLFML2A,SOD1,SYNE3,RNF165,ROR1,ADRBK2,EDNRA,ARHGEF19,IARS2,LEMD1,PSMC1,PPP2R5D,LRRFIP2,PEX6,ASL,SAMD9,ZNF432,OTUD1,AIM1L,LRRN2,KCNN4,FNIP1,ZNF692,RFX5,KNTC1,SIMC1,LRIF1,ALS2CL,HP1BP3,PARD3B,OXR1,GYLTL1B,HMG20B,RNF113A,EGFR,GLCE,GNAS,XKRX,BCAR3,ONECUT1,TSC1,SLC6A6,UTP14C,RHOBTB2,ALPK3,KIF12,KLF7,FBXW5,PROM2,GAS2L1,SLC25A24,SLC2A8,ABCG4,TDRKH,MICALL2,ARHGEF16,LRRC45,SLC25A48,SS18,SETDB2,KHNYN,FRYL,SMO,APIP,FRS3,BAG4,IGSF8,ERBB2IP,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,CANT1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,FRMD6,LRP4,FAM134A,MIER3,NOTUM,POMGNT1,FAM167A,ZNF212,SNX13,ADORA1,MLPH,GALNS,KIAA0319,BRD7,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,PHLDB3,OGDHL,POLD3,SPAG1,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,L1CAM,LRRC57 |
| 8.843e-07 | -13.94 | signal transduction | biological process | GO:0007165 | 4816 | 820 | 16441 | 2455 |
ADD1,IL15RA,GRIK2,TRIM5,DNAJC3,RET,XIAP,NRG2,IL18,BAIAP3,CA8,SPSB1,CARD10,GRM5,TP73,CALM2,DAPK2,ZYX,RGS12,ARHGAP42,PSMD1,TGFBR3,DNM2,CLDN4,CRY2,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,IL10RB,TIPARP,NEK4,TNIP1,CDA,KDELR3,PRKAR2B,ARF4,LCP1,ABR,PGF,CARHSP1,PLCG1,DNM1L,LIMK1,MYLK,MAP3K11,NOD2,HDAC1,RNASEL,ITPKA,ARF6,HSPB1,STARD13,GAB1,NUAK1,SEC61G,ITGA6,SOX9,RAB23,ZNRF3,GPSM2,MERTK,HPCAL4,LMNA,TFAP4,RAC2,MEGF8,FLRT3,FAM13B,RANBP1,MAP3K9,MYDGF,CNGA1,MAPK7,NCAM1,DGKG,NUP85,PAQR7,MAPKAPK3,SALL4,STAT4,ERO1A,SHARPIN,FHL2,CALCRL,NPHP3,ILK,ELK1,GNA11,PSMA4,RHOB,STK17A,PTPRF,IL1R1,NCOA3,FNTA,HTT,SEMA4D,ITPR1,OSMR,STK39,GDF11,NDE1,ARPC2,TRPC3,NUP58,RPS6KA3,DOCK9,DMPK,ARHGAP11A,LFNG,CD82,INPP5D,IL13RA1,MAPK4,NUF2,GRK6,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,TAX1BP3,RTKN2,ARL4D,RASGEF1A,RAB27B,MX1,SEC61B,RIPK2,FZD4,RAB38,GIGYF1,IRS2,SLC9A6,AXL,CORO1C,WFS1,SIPA1L1,WWTR1,INPP4B,TRABD2A,RGS14,ARNT,MAPK12,CTHRC1,TAOK2,NKX3-1,TNRC6C,HSP90B1,MPZL1,TRAF2,SDC4,CCM2,RASSF7,FLOT1,BTN3A1,PDIA3,PKN1,PLPPR4,ZNF219,IFT27,NFAT5,ICAM1,SGPL1,CTNNBIP1,DIRAS3,ANK1,PDCD10,IRAK1,ITGB8,KNDC1,MCF2L,GPC3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,AMOTL2,CTNNAL1,BCL9,RAPGEF2,PIK3R1,GRIN1,NEURL1B,SKA1,TXK,CNTNAP1,KIAA0141,NR1D2,ACVRL1,NR4A3,SSNA1,CENPE,ITGAV,NUP37,CD81,FOXA1,MYL9,SIGIRR,UNC93B1,BCAM,TNK1,EPAS1,AGRN,EPHA4,NDC80,NDRG2,DNAJB11,F11R,TEX2,ITPR2,PDGFB,SDC1,SPTB,RPS6KA2,NUP210,CTNNB1,SHC3,IL6ST,ARL1,MITF,PSMC2,DUSP10,TNFRSF18,SCARA3,THRB,PLK1,KCNIP3,MCTP1,MARK1,CELSR2,CR2,EZR,ARFRP1,VCP,RHEB,PLEKHB1,OPTN,PLCH1,WIPI1,CTNND1,KPNA2,PIK3C2B,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,RASA2,HLA-F,PDCL,PSMD7,RACGAP1,NCKAP1,RAB6A,DOCK11,FBLN1,DHRS3,IL18R1,ANO1,BMP2,RB1,VASP,IGF1R,KIF13B,PAK2,SELK,MDFIC,PIM1,NTN1,WNT3A,PLCB2,PSMA5,DPYSL5,RGMB,CORO2A,STRADB,TCF7,PDK3,IFIT3,CDK5R1,NMT2,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,LTBP2,PLD1,SEMA3A,IFI6,RNF146,NF2,FOXM1,TP53,DGKA,P2RX7,RHPN2,CCDC68,ERBB2,RASGRP3,STIL,BCAP31,IER3,CDK14,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,OAS3,NOTCH3,SCN2A,CTDSP2,DVL2,CTH,SULF2,SIRT1,AKT1,CDC20,PTGER4,MYL12A,DUOX1,DNAJC10,IDE,PTPRJ,RBL1,PTK7,STK38,PSMD3,IRF7,EFNA5,ARHGAP4,ZMAT1,PINK1,CPEB4,ADGRG1,TAB3,CTSB,DAP,GNAL,MCTP2,ERCC6L,CDCA8,GABRG2,PSMD10,GDF15,JAG2,CRABP2,AIP,FZD6,IL22RA1,PPP2R3A,DNAJB9,NRP2,M6PR,SGK1,IL17RA,TRIM21,BUB1,TSPAN13,SYK,CAMK2G,DUSP1,P2RX4,HES1,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,AMFR,LITAF,PPARA,MAML2,AKAP3,PELI3,BCAR1,BBS2,MAPK8IP1,DGKE,CD83,PRDX4,BCL10,DDAH1,FAT4,SCG2,TWSG1,NMI,FGF18,E2F1,PKD2,ICOSLG,NDFIP1,ARHGEF9,PTGES,ZBTB33,ARHGEF4,LAMP1,ACVR1,TXN,LGR4,HSPG2,KLC2,CUL1,GATA3,PSME1,PDGFRL,PLXNA1,PJA2,SLC20A1,CENPN,NCS1,PICK1,PAK6,CTGF,ELMO2,IL31RA,PIK3CA,ATRNL1,IRF2,TACSTD2,RCAN3,TFG,METAP2,ACVR1C,CASP9,BNIP3L,AGO4,AURKB,SAV1,ZFAND5,ULK2,RAB2B,SGPP1,AREG,TBX1,PLK2,SH2D3C,NKD1,MAPK13,EIF4EBP2,UNC5B,TRAF5,F2RL1,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,PRKAA1,AKAP17A,NOTCH2,TNFRSF19,TSPAN7,MESDC2,CALR,ITGA3,RALGPS2,PIK3AP1,CYR61,PPP4R1,PRKG1,OPN3,DAPK1,MSH2,SORL1,OSTF1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,MAST4,GPR161,EEF1D,RIMS2,SOCS5,GFPT1,PRODH,B9D2,MICB,CALM1,AMER1,DCHS1,ANO6,EPHA1,CYFIP2,KDM3A,ANTXR1,RASA1,PDE11A,FAS,DGKH,GABRD,PRKAG2,PELI2,CSNK1G1,MPP2,PIAS2,ARAP1,APPL2,CABIN1,NR4A2,EFNA1,MAP3K5,IFIH1,IRF1,SPRED1,REPS2,TCTN2,TRIP10,S100A11,RALBP1,THRA,RPS6KA1,IQGAP1,NDRG1,BCL2L1,CD274,DDR1,FLT3,GNB2,EPS8L2,ZFYVE9,NOV,APLP2,CCNA2,RALB,DOK4,CDKN1B,DAB2IP,EPHB4,IFIT1,PDE4D,TSPAN1,LGMN,MED30,NR2C1,SEMA3B,DOCK4,DMTN,PRKCQ,PYGO1,ATP1B1,ITPR3,CBL,ASB13,ALCAM,FZD7,EPHA10,FYN,JAK1,PPP2R5A,NGFRAP1,STK26,TSPAN18,KIAA1804,STAT1,PPP1CB,SLC27A1,RAB29,NRG1,NR3C2,PRKAR1A,ARHGEF3,IGFBP6,DEPDC1,CENPI,EPS8,ARL4C,HERC5,GPR180,PLD2,SPDL1,EFNB1,FGF19,LGALS3BP,TEAD3,ADGRB2,HLA-A,CKAP5,RND1,RASSF8,E2F7,GNB5,PTEN,FUT8,PRC1,CD9,SGK3,SLC44A2,ERBB3,MAP3K7,CITED2,CNPY3,SPRY2,TRIM62,NCOA2,MSH6,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,ZWINT,ARAP2,MPP1,FURIN,DIAPH2,YES1,FOS,GPLD1,RGS9,FGFR2,RIN3,RYK,RABL6,GRIN2D,GPER1,LRRK1,FZD5,MELK,RGMA,CCNC,LTBP1,CASP3,KIF2C,CACNB4,DNER,KREMEN1,TRIM68,PTCHD4,SH3KBP1,HTR1D,ZFYVE16,EPCAM,RAB15,ZCCHC12,DPYSL2,TSPAN6,SIVA1,AKR1B1,RAB20,CTTN,MYH14,PTPRE,IL1RAP,RASGRP1,CYP1B1,TRIM8,CENPA,CXXC5,USP18,ITCH,ARHGDIB,ROR1,ADRBK2,STK17B,EDNRA,CXXC4,MDK,GPRC5B,MADD,CAB39,ADIPOR1,RAP1GAP,NRGN,PPP2R5D,PSMC1,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,PPP1R12A,ASB9,ATP6V1E2,CALM3,TEC,PHLPP1,DUSP5,NOXA1,CA2,LRRN2,OCRL,DIAPH2-AS1,PRKCI,FNIP1,KNTC1,HLA-C,NPTN,C10orf54,ZRANB1,CCDC88A,MDFI,ELK3,PDE5A,EGFR,RHPN1,GNAS,BCAR3,ONECUT1,TSC1,INSR,PLPP3,NFKBIA,RAB31,RHOBTB2,NXPH4,YOD1,JAK3,TOB1,RARG,COL16A1,DRD1,SORBS1,SPC25,IL15,SLC2A8,PSME2,SOD2,PDIA5,IL27RA,MRAS,EXT2,ARHGEF16,SS18,ARTN,KIF14,SMO,GOT1,DIXDC1,NFKB2,F2R,PDIA6,FRS3,CHP1,MAP3K3,BAG4,KREMEN2,PTPRU,ERBB2IP,CD40,DUSP4,DOCK5,CDC25C,CASP4,MAP3K6,ARHGAP35,SOCS3,STAT6,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,PLXND1,SGOL1,ABCA1,LIFR,SORT1,ARHGEF11,ARHGEF7,CIT,LRP4,TGFBR1,AES,NOTUM,ITGA2B,XPR1,HMGXB4,SYDE2,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,ZDHHC13,BRD7,IQGAP3,RAB3B,ADAM17,CENPC,WNT10B,DEPDC4,NR4A1,NDRG3,LEPR,ARHGAP24,CTSL,HLA-B,CD8A,CASP7,RND3,RAP2C,UBE2D2,DTX4,UACA,ARRB1,GEM,ATP6V1C1,SOX8,L1CAM,AHR,CD33,NGEF |
| 8.855e-07 | -13.94 | regulation of localization | biological process | GO:0032879 | 2322 | 425 | 16441 | 2455 |
DOC2A,LAMP1,ACACB,TXN,ACVR1,LGR4,IBTK,TRIM5,PNPLA2,ATP8A1,RET,CACNA2D2,GATA3,LGI3,IL18,PLXNA1,SYTL4,CAMK1D,CCNB1,VASH1,BARD1,PICK1,NCS1,CALM2,DAPK2,TGFBR3,STIM1,CABP1,KCNS3,DNM2,CRY2,TACSTD2,SEMA3G,PIK3CD,TMEM37,PACSIN1,VPS11,ACVR1C,BNIP3L,NBPF3,PRKAR2B,SLC25A5,PNKD,RAB2B,LCP1,ABR,ENPP1,PLCG1,SLC25A4,DNM1L,MYLK,NKD1,FAM110C,NOD2,SARAF,RNASEL,ARF6,HSPB1,F2RL1,SLC31A2,GAB1,DDX58,SEMA6B,SCN5A,NFKBIE,TBC1D1,HLA-E,SOX9,PRKAA1,RAB23,SLC25A27,MERTK,LMNA,CALR,RAC2,ITGA3,CYR61,RIMS3,MEGF8,NEK2,DAPK1,SORL1,CACNA1D,MAPK7,SYTL3,NUP85,RIMS2,EPB41L5,GCC2,KCNJ12,MMD,CALM1,ANO6,ERO1A,WHSC1,PLS1,KIF20B,EPHA1,MEST,ILK,TP53INP2,RHOB,PLIN5,STX3,AP1AR,PRKAG2,HTT,SEMA4D,ITPR1,ARAP1,OSCP1,STK39,EFNA1,CFAP20,TRPC3,NUP58,TMEM173,EHD1,DMPK,THRA,IQGAP1,PKP2,BCL2L1,CD274,PRKACA,APC2,NOV,CDH1,SP100,RALB,DACT1,CDKN1B,TAX1BP3,DAB2IP,PDE4D,ACSL4,TSPAN1,RAB27B,MYT1,TMBIM1,SCN3A,SEMA3B,DOCK4,PFKFB2,DMTN,SYNE2,VPS4B,UTRN,PRKCQ,ATP1B1,CBL,ITPR3,SNX12,FZD7,IRS2,FYN,STX10,PPP2R5A,CORO1C,WFS1,AXL,WWTR1,INPP4B,NRG1,RAB29,PRKAR1A,TCAF1,NKX3-1,TRAF2,SDC4,FLOT1,CBLL1,PLD2,ANO9,PKN1,KCNC4,ETS1,SRPX2,FGF19,ICAM1,SIX4,WWP2,NEO1,SNTA1,CXCL16,PDCD10,OXCT1,GNB5,PTEN,KCNK5,GPC3,FAM20B,SGK3,BAX,ADAM15,TMBIM6,MAPK11,ERBB3,CITED2,TPCN1,HCN3,RASGRF1,CASK,MPP1,RAPGEF2,PIK3R1,GRIN1,FURIN,VAMP3,PIM3,GPLD1,NUCB1,LDLRAP1,ACVRL1,SYT7,NR4A3,ITGAV,GPER1,FHL1,NUP37,FZD5,ARSB,CD81,EXPH5,ILDR1,ITPR2,HDAC6,CACNB4,PDGFB,SDC1,ERP29,SLC8B1,ZFYVE16,EPCAM,NKAIN3,RAB15,NUP210,CTNNB1,SIVA1,DPYSL2,PASK,ABCA2,DLG1,TRPC1,TNFRSF18,RAB20,MYRIP,RASGRP1,CYP1B1,KCNIP3,TRIM8,CELSR2,EZR,ARHGDIB,NKAIN1,CLCN2,CDK1,DPYSL3,TRIM9,KCNMB4,RAB11FIP1,CAB39,RAP1GAP,TC2N,MIIP,PRSS8,BMF,ARAP3,PPP1R12A,LGALS3,SERPINE2,BVES,UBASH3B,FXYD3,CALM3,RACGAP1,NCKAP1,FBLN1,IL18R1,ANO1,SSX2IP,CORO1B,BMP2,RB1,TIMP1,CA2,IGF1R,PFKL,GATA2,KCNN4,SLC30A6,PRKCI,FXYD5,MDFIC,NTN1,WNT3A,MDFI,SPATA13,EGFR,CDK5R1,GNAS,ONECUT1,INSR,PLPP3,CSF1,TMEM30A,CDCA5,NFKBIA,EGFL7,YOD1,ATP1B3,PLD1,JAK3,SEMA3A,DRD1,PROM2,LZTFL1,SORBS1,KCNAB3,NF2,TP53,ERBB2,P2RX7,COL18A1,MICALL2,EMP2,BCAP31,ARHGEF16,SYTL2,PER2,IER3,PDGFA,SVBP,KIF14,PLCG2,REEP1,BCL6,SMO,CDH3,TWIST1,EPB41L4B,SCN2A,F2R,HSPA2,CHP1,SIRT1,PPIF,CLCN3,ERLEC1,BAG4,AKT1,PTPRU,CCSAP,PTGER4,CD40,DOCK5,DAG1,PTGS2,ATP1A1,PTPRJ,EFNA5,PLXND1,SYT13,ARHGAP4,ABCA1,BIN1,ANXA3,PINK1,PACSIN2,CD63,ADGRG1,ARHGEF7,PSMD10,SELL,TGFBR1,HMGN3,JAG2,NRP2,PPP2R3A,ITGA2B,HDAC9,KIF5B,CARD8,ADORA1,ADRBK1,LLGL2,CDK16,BMP7,UBE2J1,SGK1,TSPAN13,CPLX1,SYK,CAMK2G,MYO5A,P2RX4,SUN2,HES1,ADAM17,RAB3B,RHOA,SYBU,LITAF,PPARA,RGCC,BCAR1,BORA,BBS2,MAP1B,USP6,BANK1,SWAP70,PRCP,SPINT2,FGF18,RAP2C,NETO2,E2F1,ARRB1,PKD2,SPCS3,NDFIP1,TBC1D4,PKIA,ABCG1 |
| 8.909e-07 | -13.93 | Cytokine Signaling in Immune system | REACTOME pathways | R-HSA-1280215 | 539 | 122 | 8202 | 1235 |
SPRED1,TRIM2,TRIM5,PSME2,IQGAP1,INPP5D,ERBB2,NRG2,CUL1,RASGRP3,IL18,PSME1,PDGFB,PRKACA,TRIM68,SPTB,CALM2,PDGFA,PSMD1,NUP210,SP100,SHC3,IL6ST,PSMC2,PIK3CA,DUSP10,IRF2,DAB2IP,TNFRSF18,IFIT1,PIK3CD,OAS3,NFKB2,RASGEF1A,IL1RAP,RASGRP1,FRS3,MAP3K3,MX1,TRIM8,RIPK2,USP18,DUSP4,CD40,CBL,SOCS3,IRS2,PLCG1,FYN,JAK1,PPP2R5A,PSMD3,TRIM45,STAT1,MAP3K11,NOD2,NRG1,SPTBN5,KPNA2,IRF7,RNASEL,PPP2R5D,PSMC1,DDX58,INPPL1,TAB3,HLA-E,HLA-F,TRAF2,RASA2,PSMD7,PSMD10,HERC5,CALM3,TEC,FGF19,DUSP5,ICAM1,HLA-A,ITGA2B,IRAK1,TRIM3,TRIM21,CD70,TNFRSF12A,ERBB3,HLA-C,MAP3K7,NCAM1,TRIM62,NUP85,SYK,CAMK2G,PSMA5,DUSP1,RASGRF1,ADAM17,PSMB4,IFITM3,RAPGEF2,PIK3R1,CALM1,GRIN1,TRIM35,PELI3,YES1,IFIT3,PSMA4,EGFR,RASA1,IL1R1,HLA-B,FGFR2,PELI2,FGF18,ARRB1,GRIN2D,NUP37,JAK3,IFI6,NUP58,IRF1 |
| 9.134e-07 | -13.91 | KOYAMA_SEMA3B_TARGETS_DN | MSigDB lists | KOYAMA_SEMA3B_TARGETS_DN | 377 | 90 | 17758 | 2588 |
MYL9,TRIM24,NQO1,BROX,CTDSPL,TAP1,RGS20,ARFGEF1,CUL1,MRAS,LACTB2,FAM101B,CENPN,UHRF1BP1L,LMO4,LHX6,PSMC2,SMO,AKR1B1,RASGEF1A,PLK1,ATL1,SERTAD4,DRAP1,PLEKHO1,PRKAR2B,ROR1,CD40,ALCAM,FZD7,IRX3,SLC44A3,CXXC4,ACYP1,STAT6,TRAF3IP1,ZNF704,SGOL1,TRAF5,NR3C2,LNP1,CBX7,CHCHD7,FRMD6,CALB2,PRKAA1,CTSZ,PLD2,JAG2,ETS1,DHRS3,NFAT5,PGAP1,XPR1,SYDE2,PDIA4,CCDC92,TNS3,PHF7,GATA2,CALD1,GALNS,FCHO1,NEK2,CKS1B,FAM102A,CD70,ABCD1,RFX5,TAGLN2,PANX2,OSGIN1,TSPAN33,ATP2B1,FARP2,EPHX1,C9orf9,SYPL1,HES1,PSMB4,DIAPH2,ATP8B3,AIF1L,SLCO4A1,NFKBIA,SH3BP4,ARRB1,EGFL7,EFNA1,ICOSLG |
| 9.443e-07 | -13.87 | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN | 188 | 53 | 17758 | 2588 |
LAMP1,AVPI1,EPAS1,CTSB,APOO,MCOLN3,HEXB,ETNK1,RASGRP3,NENF,NTAN1,SPR,BCAP31,LMNA,TNS3,CA2,EFR3A,DDHD2,COL6A1,MITF,PAPSS1,CKS1B,TUBG1,TAX1BP3,VAT1,STEAP3,GOT1,TECR,CTSD,ALDH3A2,GM2A,FAM69A,FAH,TIMP2,MMD,ACO1,SLC17A5,ICMT,CYB5A,PRDX4,ATP1A1,CORO1C,SETD3,DBI,MAPK13,MDH1,ATP6V1C1,PLOD3,ARSB,CD81,HSPB1,ANXA11,DLAT |
| 9.443e-07 | -13.87 | GSE17721_12H_VS_24H_POLYIC_BMDM_UP | MSigDB lists | GSE17721_12H_VS_24H_POLYIC_BMDM_UP | 188 | 53 | 17758 | 2588 |
PLA2G4A,MYL9,CCDC109B,FAM92A1,IL15RA,DHPS,CYP2J2,SLC41A1,ITGA6,PDIA3,PHLDA1,TNFSF9,FGF19,NRP2,APPBP2,PLS3,RCN1,PDGFA,IGSF9,CTSC,FRYL,MITF,PAPSS1,SLC30A6,CAPG,TPST1,ECI2,RAB20,TFG,MINPP1,NFKB2,IL1RAP,CCDC88A,PMPCB,CASK,TIMP2,RIPK2,TNIP1,BCL9,USP18,NUSAP1,PSMA4,RHOB,PAFAH1B3,TRAF5,CD81,NDST3,PTGES,TOB1,CPPED1,CYBRD1,JARID2,RRAGD |
| 9.457e-07 | -13.87 | AMIT_SERUM_RESPONSE_120_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_120_MCF10A | 63 | 25 | 17758 | 2588 |
SUN1,CD55,CDKN1C,TESK1,PLAUR,SOX9,C3orf52,SERTAD3,EZR,BCAR3,BMP2,IRS2,ETS2,RND3,SETD3,CSTF2,ATP8B1,TRIM21,DUSP10,KLF5,PIM1,PPP2R5D,MAFF,ISOC1,GCNT1 |
| 9.675e-07 | -13.85 | purine ribonucleoside binding | molecular function | GO:0032550 | 1795 | 337 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,KIF13A,PIF1,AURKB,RAB2B,ARF4,ULK2,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,TRANK1,RALB,FICD,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,GALK1,HSP90B1,TAOK2,ATP9A,ARL4C,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,OPLAH,PCCB,CASK,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PSMC2,PAPSS1,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,PSMC1,RRAGD,PRKAA2,LMTK3,RUNX2,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ABCC1,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,DYRK3,PINK1,TOR4A,SHPRH,CIT,GNAL,GNE,ERCC6L,TGFBR1,KIF5B,TOP2A,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,MYO5A,ATP2B1,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,RAP2C,UBE2D2,GEM,UBE2C,HIPK3,ABCG1 |
| 9.696e-07 | -13.85 | LINSLEY_MIR16_TARGETS | MSigDB lists | LINSLEY_MIR16_TARGETS | 193 | 54 | 17758 | 2588 |
LMO7,CDS2,NLRX1,TMEM55B,EPHA4,BIK,KIF23,CCDC68,UBE2Q1,EXT2,CARD10,SIRPA,ZFYVE9,M6PR,TFAP4,WEE1,E2F7,BTG3,RNF128,GNB5,DDHD2,WWP1,CRY2,NCEH1,MYBL1,TIAM1,GFPT1,RAB3B,ELK3,RFK,TACC1,MICB,CBX6,KIF1C,SLC11A2,UBAC1,ANLN,NUBP1,SFXN5,TRUB1,DCP2,CDCA4,CASP7,ATXN7L3,RAB11FIP2,SETD3,LIMK1,PHLPP2,E2F1,SPAG7,CLIP4,OSCP1,RPS6KA3,RGMA |
| 9.696e-07 | -13.85 | GSE3982_MAC_VS_NKCELL_UP | MSigDB lists | GSE3982_MAC_VS_NKCELL_UP | 193 | 54 | 17758 | 2588 |
LAMP1,CMAS,REPS2,DLGAP5,GALNT12,SLC25A13,HEBP1,APOO,ABCG2,CDCA8,KCTD12,FTH1,MGST2,MERTK,ARHGEF40,CMTM6,PPP2R3A,M6PR,SNX13,PTEN,PAQR5,GALNS,H2AFY,KCTD3,MYO5A,HMMR,BAG4,NRBF2,PLAUR,KIF1C,HTATIP2,NUSAP1,ERP44,TNS1,MCFD2,ASB13,IDH1,CD83,TIMP3,CTNS,CCDC6,PRDX3,P4HA2,CSF1,WWTR1,PLA2G15,RAB11FIP1,PGRMC1,PDXK,PLIN3,MAD2L1BP,ACOT7,CYBRD1,DLAT |
| 9.916e-07 | -13.82 | HALLMARK_IL2_STAT5_SIGNALING | MSigDB lists | HALLMARK_IL2_STAT5_SIGNALING | 198 | 55 | 17758 | 2588 |
CASP3,TTC39B,CDKN1C,NDRG1,ITGA6,SELL,CTSZ,BCL2L1,GALM,DHRS3,PHLDA1,SNX9,IL18R1,NCS1,MXD1,BMP2,SPP1,CA2,IGF1R,COL6A1,CAPG,TNFRSF18,AHCY,PIM1,ETV4,TIAM1,CKAP4,GPX4,FAH,P2RX4,PLSCR1,IFITM3,SLC39A8,FURIN,ALCAM,RHOB,CD83,GABARAPL1,MAPKAPK2,NCOA3,ENPP1,SWAP70,TWSG1,CSF1,LRIG1,ABCB1,SH3BGRL2,NFKBIZ,SERPINB6,ITGAV,SPRY4,CD81,MAFF,AHR,RRAGD |
| 9.916e-07 | -13.82 | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | MSigDB lists | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 198 | 55 | 17758 | 2588 |
CASP3,SERPINE2,LGALS3,CPT2,CYP2J2,CD82,EPS8,SDC4,PPFIBP2,TP53,PSME1,NTAN1,SEPP1,GSTP1,AIP,BCAP31,TOP2A,GNB5,CDH1,CTNNB1,PFKL,KLF3,BAX,FXYD5,OSTF1,AHCY,CPE,S100A13,SLC35A1,HMMR,SEC23A,UFD1L,CLCN3,SOD1,CD55,ARHGDIB,FOS,GNA11,CASP4,ARF4,IL1R1,ENPP1,FNTA,DDOST,HOXA9,NFKBIA,ABCB1,PPP1CB,TLE1,SERPINB6,ACADM,FHL1,PSMC1,TOB1,ANXA11 |
| 1.003e-06 | -13.81 | regulation of cell cycle process | biological process | GO:0010564 | 540 | 122 | 16441 | 2455 |
CCNC,DLGAP5,FOXM1,CAST,PSME2,NDRG1,CUL4B,CTDSPL,PTTG1,TP53,CUL1,PSME1,CCNL1,CCNB1,PRKACA,PDGFB,STIL,FANCI,IER3,TP73,NPM2,CALM2,SUSD2,CCND1,CYP1A1,CCNA2,PSMD1,RPS6KA2,CTNNB1,CTGF,DACT1,KIF14,PSMC2,PLK4,CDKN1B,DAB2IP,HSPA2,CTDSP2,PLK1,PSRC1,AKT1,CDC20,VPS4B,PRKCQ,NUSAP1,PKMYT1,AURKB,CCNF,ANLN,CDC25C,CDK1,JADE1,CCNB3,PLK2,PSMD3,OVOL1,CHMP4B,XRCC3,MAD2L1BP,GEN1,E2F8,PSMC1,MIIP,CTDSP1,PRKAR1A,BIN1,CIT,SOX9,PSMD7,CALM3,PSMD10,KIF23,RACGAP1,CALR,TFAP4,E2F7,RB1,IGF1R,PTEN,CENPJ,BMP7,FBXO7,NEK2,MSH2,H2AFY,BRD7,BUB1,KANK2,ERCC2,PIM1,KNTC1,PSMA5,DUSP1,ADAM17,RHOA,PSMB4,WNT10B,HMGN5,CALM1,RGCC,KIF20B,BORA,KIF11,NUBP1,PSMA4,EGFR,CDK5R1,NUDT16,INSR,TJP3,FGFR2,CDCA5,E2F1,FAM83D,AURKA,PKD2,GPER1,FHL1,CENPE,UBE2C,ESPL1,PKIA |
| 1.024e-06 | -13.79 | RIGGI_EWING_SARCOMA_PROGENITOR_DN | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_DN | 174 | 50 | 17758 | 2588 |
AVPI1,RUNX2,DLGAP5,ZNF395,DEPDC1,IGFBP6,GALNT12,BACE1,CUL4B,CDCA3,GPSM2,DHRS3,TNFRSF19,FBLN1,SNX9,PHLDA1,CARD10,NRP2,ASPHD2,TOP2A,RPS6KA2,TGFBR3,SRPX,ALDH1A3,AIM1,PRC1,SCARA3,FAR2,MOXD1,RAB27B,COL6A2,MFI2,ASPM,PBK,NUSAP1,DUSP4,ITPR3,ANLN,GLT8D2,EGFR,DPYSL3,IL1R1,NR1D2,CSGALNACT1,FAM83D,TRIOBP,TANC2,OSR1,GLCCI1,F2RL1 |
| 1.029e-06 | -13.79 | BRUINS_UVC_RESPONSE_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_LATE | 1078 | 213 | 17758 | 2588 |
MYL9,AGRN,GNPDA1,TMEM86B,TMEM41B,SUDS3,TEX2,NANS,ITPR2,DPP8,MAP1LC3B,LTBP3,PICK1,PLS3,MAGOHB,UBE2T,ELMO2,P4HB,OSBPL3,SLC46A1,PSMC2,SLC44A1,TUBG1,RAB20,NFU1,RP2,ACOX2,RCAN3,TLN2,TRAM1,NEB,DDX59,ODF2L,LOC81691,PCGF5,SGCE,CD55,TNIP1,CDA,KDELR3,MRPS18A,LOXL2,ICMT,MYOM1,CDK1,POR,COL12A1,GINS4,PRIM1,KDSR,MFAP3L,ENPP1,NEIL1,AREG,GDE1,FAM114A1,CAB39,MRPS28,GLA,TTC39C,CHPT1,PSMC1,CAPN1,FAM89A,LRRFIP2,PPP1R12A,TBC1D1,RASA2,ELOVL7,HERC6,ANO1,MYO5C,SH3D21,ZCCHC17,ICAM5,VASN,COL6A1,FBXO7,TBCD,DAPK1,MSH2,TPST1,PIKFYVE,SLC12A2,KANK3,PSMA5,FADS2,ELK3,KLK5,PRSS23,SPA17,FBXO8,KCTD20,EPHA1,PSMA4,RHOB,NMT2,SCARB2,FNTA,DCK,MFSD2A,NAB2,MATN2,RAB31,FAM83D,PIAS2,FGD6,DONSON,SAMD8,PLIN3,AKIP1,C17orf75,TOB1,MTM1,KCNAB3,FAM92A1,IL15,CAST,PTTG1,DGKA,ETNK1,PDIA5,FAM198B,AIFM2,EPS8L2,RAD23A,RCN1,APOBEC3B,SRPX,DOK4,BCL6,STEAP3,DIXDC1,ACSL4,RNASEH2A,PDIA6,LOXL1,SEC61B,LGALS8,KIAA0040,DRAP1,HTATIP2,SYP,CD40,MYL12A,TAPBP,NGFRAP1,STAT6,WWTR1,MLKL,PDXK,B4GALT3,KDELC2,PRKAR1A,MRPS9,CMAS,CTHRC1,GCLM,PCOLCE,PACSIN2,FARP1,KLHL13,DCAF7,ARHGEF7,RASSF7,EPS8,SERPINB9,PSMD10,COL4A5,FBXO6,HDGFRP2,PARM1,C16orf74,PDCD10,OXCT1,PTEN,CDK16,UBE2J1,GTF2F2,TMBIM6,TRIM21,ACTA2,MAP3K7,CITED2,CRTAP,ATP2B1,MYO5A,FAH,PCCB,PGM1,FBLN5,PLSCR1,CCDC34,DIAPH2,TTC7A,BLVRA,CRISPLD2,CDK5RAP1,ENDOD1,DDAH1,SWAP70,ACADSB,TWSG1,NMI,E2F1,ABCB1,CSTF2,ERAP1,GRIN2D,ATP6V1C1,ARSB,AHR,ABCG1 |
| 1.045e-06 | -13.77 | cytoplasmic vesicle | cellular component | GO:0031410 | 1201 | 235 | 17570 | 2579 |
SUN1,DOC2A,LAMP1,UNC93B1,KLK10,IL15RA,ATP8A1,HEXB,TRAPPC8,F11R,TGOLN2,LGI3,SYTL4,SNX9,PDGFB,MAP1LC3B,ERP29,PICK1,NCS1,SH3KBP1,DAPK2,AP1M2,ENTPD4,P4HB,LMAN2L,STEAP2,CAPG,DNM2,ABCA2,RAB20,RP2,MARCH2,PACSIN1,MYRIP,CPE,SMAGP,LAMP3,LAMP2,VPS11,SOD1,SNTB2,ITCH,ARHGDIB,SLC17A5,MCFD2,ULK2,OPTN,DPYSL3,CXXC4,TRIM9,TBC1D17,GPRC5B,DNM1L,WIPI1,AREG,KCNK1,ATP7B,RAB11FIP1,ARRDC1,PIK3C2B,ARF6,POMT1,APBA2,NRGN,ANXA11,PCSK5,PIFO,BMF,SERPINE2,HLA-E,HLA-F,RAB23,ATP6V1E2,RACGAP1,RAB6A,APBA1,MARCH8,CALR,RAC2,TIMP1,SNX18,RINL,ZNRF2,OCRL,FCHO1,AHCY,CADPS2,HLA-C,PIKFYVE,CTSD,WNT3A,GAD1,SYTL3,C9orf72,CCDC88A,CKAP4,TMED2,GPR161,SNX7,KDELR1,C9orf9,KLK5,VEZT,ATP8B3,TP53INP2,C3orf58,EGFR,STX3,GNAS,EPN3,AP1AR,HTT,TMEM30A,ITPR1,SH3BP4,RAB31,ARAP1,DYSF,KLK7,ATP1B3,PLD1,TMEM173,RUSC1,PROM2,PLA2G4A,SLC2A4,GPR107,SLC2A8,ERBB2,BCL2L1,SAYSD1,PHLDA1,EMP2,BCAP31,APPBP2,SYTL2,CD46,PDGFA,ATP6V0B,N4BP3,SMO,DAB2IP,ECE1,LMAN1,RAB27B,LOXL1,PDIA6,FLOT2,DVL2,EBAG9,CHP1,MYO5B,SEC23A,CLCN3,NRBF2,FZD4,DMTN,SEPT6,SYP,SLC11A2,RAB38,GABARAPL1,ATP1A1,STK26,SLC9A6,RAB29,SYT13,ABCA1,COPG1,ARFGEF3,ANXA3,SORT1,PACSIN2,GOLIM4,HSP90B1,TAOK2,CD63,RUSC2,BACE1,CTSB,FLOT1,PDIA3,CTSZ,PKN1,HLA-A,FZD6,ITGA2B,PDIA4,KIF5B,CTSC,CDK16,SGK3,CD9,ZDHHC13,ADAM15,IGFBP2,SYK,CAMK2G,MYO5A,AMOTL2,SYPL1,RAB3B,ERMAP,DENND1B,RAPGEF2,SYBU,GRIN1,FURIN,VAMP3,COL7A1,GGH,AKAP3,FAM109A,FNDC3A,RNPEP,CRISPLD2,HLA-B,NUCB1,LDLRAP1,SERPINA1,CTNS,FGFR2,RAB11FIP2,SYT7,SCG2,CTSV,RIN3,FAM3C,ARRB1,ITGAV,GPER1,ATP6V1C1,FZD5,TBC1D4,OCLN |
| 1.046e-06 | -13.77 | wound healing | biological process | GO:0042060 | 667 | 145 | 16441 | 2455 |
MYL9,CASP3,KLC2,GATA3,F11R,ITPR2,KIF2C,CCNB1,PDGFB,SDC1,KIF26A,CALM2,WEE1,STIM1,PIK3CA,IRF2,KIF22,FGFR1OP2,RASGRP1,TUBA4A,LAMP2,SOD1,KLK6,PRKAR2B,F12,LCP1,OPTN,PLCG1,KCNMB4,ARHGEF19,HPSE,HDAC1,HSPB1,F2RL1,MAFF,SERPINE2,ITGA6,DGKQ,CALM3,KIF23,RACGAP1,TEC,DOCK11,MERTK,FBLN1,CORO1B,RAC2,ITGA3,TIMP1,CYR61,GATA2,PRKG1,WNT3A,DGKG,ELK3,CALM1,ANO6,HMG20B,PDE5A,SCRIB,ILK,GNA11,RHOB,PDE11A,RASGRP2,DGKH,GNAS,ITPR1,DYSF,ATP1B3,CBX5,TRPC3,EHD1,IRF1,DOCK9,PLA2G4A,KIF3C,PAPSS2,INPP5D,TP53,DGKA,ERBB2,PRKACA,DDR1,PDGFA,NOV,CYP4F11,PLCG2,CDH3,EPB41L4B,LMAN1,F2R,ENPP4,AKT1,PRKCQ,ATP1B1,ITPR3,CD40,MYL12A,FZD7,FYN,ABHD12,AXL,PTK7,NRG1,PRKAR1A,CD63,SDC4,HABP4,SELL,TGFBR1,ETS1,ITGA2B,FZD6,SIRPA,PDCD10,CD9,ADAM15,ERBB3,AK3,SYK,ATP2B1,RHOA,ADAM17,WNT10B,PLSCR1,BCL9,PLAUR,PIK3R1,PPARA,C1GALT1C1,YES1,KIF11,BCAR1,DGKE,ARHGAP24,TIMP3,SERPINA1,ACVRL1,SYT7,PRCP,ARRB1,ITGAV,CENPE,L1CAM |
| 1.059e-06 | -13.76 | negative regulation of protein metabolic process | biological process | GO:0051248 | 1025 | 208 | 16441 | 2455 |
SIGIRR,CASP3,PPP4R4,ST13,IBTK,DNAJC3,XIAP,NDRG2,PSME1,CCNB1,HDAC6,RIC1,PHF1,TP73,CALM2,CDKN2C,PSMD1,CTNNB1,ZFP36,RGS3,PSMC2,DLG1,DUSP10,CRY2,PLK1,CD55,TNIP1,ITCH,PBK,EZR,AGO4,PRKAR2B,POR,PIAS3,ENPP1,CAMK2N2,LIMK1,TRAF3IP1,PPP2R4,SERPINB6,EIF4EBP2,SERPINI1,SPRY4,HSPB1,F2RL1,PSMC1,LMTK3,CDKN1C,SERPINE2,DNAJB2,UBASH3B,PDCL,RAB23,PSMD7,CALM3,FBLN1,DUSP5,SH3RF2,MECOM,TFAP4,CALR,RB1,TIMP1,IGF1R,PAIP2B,FBXO7,PAK2,DAPK1,FNIP1,SORL1,PSMA5,SOCS5,CALM1,HMG20B,EIF2AK1,EPHA1,ILK,KDM3A,PSMA4,RANBP9,EGFR,FAS,TSC1,PRKAG2,HTT,SEMA4D,PLPP3,STK39,YOD1,JAK3,SERPINB1,TOB1,IFI6,CTBP1,RPS6KA3,XDH,DRD1,SPRED1,NF2,FOXM1,INPP5D,RPS6KA1,PSME2,CAST,CTDSPL,PTTG1,TP53,P2RX7,PATL2,SYTL2,PER2,CD46,APLP2,SVBP,DACT1,CDKN1B,DAB2IP,TWIST1,PDE4D,DLG3,CDKN2D,FLOT2,CTDSP2,CHP1,SIRT1,CAMSAP3,TIMP2,ERLEC1,BAG4,AKT1,DMTN,CDC20,PKMYT1,DUSP4,SNX12,DAG1,C3orf33,SOCS3,DNAJC10,FYN,IDE,PTPRJ,STK38,CORO1C,PSMD3,WWTR1,NRG1,RGS14,PRKAR1A,CTDSP1,ARFGEF3,PINK1,FARP1,TNRC6C,CPEB4,TRAF2,SERPINB9,PSMD10,PKN1,TRIB2,GSTP1,TIPRL,SH2D4A,CD109,SNTA1,RNF128,PTEN,BMP7,GPC3,CST3,UBE2J1,BAX,H2AFY,TRIM21,BUB1,HEXIM2,RAG1,CNOT6L,SPRY2,CRTAP,DUSP1,PSMB4,PLAUR,GCLC,FURIN,COL7A1,FXR2,MAPK8IP1,LEMD2,CNOT2,CDK5RAP1,BANK1,TIMP3,SWAP70,SERPINA1,PRDX3,SPINT2,NMI,SERPINB5,ARRB1,ITGAV,GPER1,LRRK1,UBE2C,CPEB2,HIPK3,PKIA,JARID2 |
| 1.063e-06 | -13.75 | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | MSigDB lists | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | 179 | 51 | 17758 | 2588 |
PARP12,ENO2,REPS2,MPZL1,DNAJB2,HABP4,C6orf106,PKP2,AKAP17A,PLAC1,F11R,BAIAP3,MAP1LC3B,CYP26A1,APOBEC3B,TIMP1,ALPP,CD9,PIK3CD,CDKN2D,HSPA2,MLEC,TIMP2,TEF,RAPGEF2,ITCH,C3orf52,KDELR3,SPTLC2,STX3,ARF4,NMT2,OPTN,RASGRP2,FUCA1,PGF,RGS9,KLF12,CGREF1,ITPR1,CLMN,IRF7,SERPINI1,FHL1,GDF11,PLIN3,NRGN,LIFR,CSRP2,NXT2,EHD1 |
| 1.066e-06 | -13.75 | cellular response to stimulus | biological process | GO:0051716 | 6201 | 1032 | 16441 | 2455 |
GRIK2,RET,CCNO,BAIAP3,SPSB1,CARD10,GRM5,PHYHIP,UBE2T,DNM2,CLDN4,CRY2,PPP1CA,TIAM1,IL10RB,TIPARP,CPE,NEK4,CDA,KDELR3,PRKAR2B,ARF4,GINS4,LCP1,ABR,ENPP1,CARHSP1,PLCG1,NOD2,HDAC1,RNASEL,ITPKA,HSPB1,STARD13,SCN5A,SEC61G,ITGA6,RAB23,GPSM2,HPCAL4,ATG4A,TFAP4,RAC2,ZCCHC17,MEGF8,RIMS3,FLRT3,RANBP1,MAP3K9,USP1,ALPK1,MYDGF,CNGA1,MAPK7,DGKG,NUP85,PAQR7,REC8,MAPKAPK3,ERO1A,SHARPIN,FHL2,ELK1,NPHP3,PSMA4,GNA11,IL1R1,FNTA,DGAT2,STK39,GDF11,NUP58,TMEM173,DOCK9,DMPK,NQO1,LFNG,INPP5D,CD82,PTTG1,MAPK4,GRK6,MGST2,CDH1,SH3BP1,TAX1BP3,RASGEF1A,MX1,SEC61B,RIPK2,SYP,XRCC6BP1,GIGYF1,ALDH3B1,CDK19,SHROOM3,CORO1C,WFS1,AXL,MAPK12,CTHRC1,HSP90B1,MPZL1,TRAF2,CCM2,SDC4,HABP4,FLOT1,BTN3A1,PLPPR4,ZNF219,IFT27,NFAT5,SGPL1,CTNNBIP1,DIRAS3,PDCD10,ITGB8,KNDC1,GPC3,CST3,BAX,IGFBP2,PARP9,OPLAH,PIK3R1,UBE2A,CNTNAP1,PLOD2,RAB11FIP2,SLC35B3,NR4A3,OSER1,SSNA1,ITGAV,CMPK2,OSR1,CD81,WDR45B,PHC1,BCAM,TNK1,EPAS1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,ITPR2,SPTB,FANCI,CPNE2,RPS6KA2,NUP210,CTNNB1,NPNT,P4HB,IL6ST,ARL1,PAPSS1,PSMC2,MITF,SCARA3,PLK1,THRB,KCNIP3,MARK1,CELSR2,NFE2L1,CR2,ARFRP1,SESN1,KDM4D,KPNA2,MYL12B,RRAGD,RUNX2,LGALS3,DNAJB2,RASA2,PDCL,PSMD7,RAB6A,NCKAP1,FBLN1,ANO1,KIF13B,SELK,AHCY,PIM1,NTN1,WNT3A,DPYSL5,RGMB,STRADB,PDK3,NMT2,CDK5R1,RASGRP2,PHLPP2,PLD1,SEMA3A,USP43,RAD21,TMX4,TP53,P2RX7,RHPN2,STIL,BCAP31,IER3,TTC21B,PDGFA,BCL6,CDH3,NOTCH3,OAS3,CTDSP2,SULF2,PPIF,ERLEC1,AKT1,PTGER4,ATP13A2,PTGS2,PTPRJ,IDE,RBL1,STK38,MAOA,XRCC3,EFNA5,IRF7,ARHGAP4,ZMAT1,PINK1,CPEB4,TAB3,CTSB,GNAL,MCTP2,CDCA8,ERCC6L,GDF15,AIP,IL22RA1,DNAJB9,FZD6,NRP2,M6PR,UBE2J1,TFAP2A,SGK1,IL17RA,TRIM21,TSPAN13,SYK,DUSP1,P2RX4,HES1,RHOA,PLAUR,MAML2,BBS2,TXNDC11,DGKE,BCL10,DDAH1,SCG2,NEIL3,FGF18,E2F1,ICOSLG,PTGES,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,CUL1,PSME1,PDGFRL,PJA2,PICK1,PAK6,CYP1A1,FOSB,POLL,PIK3CA,IRF2,TACSTD2,METAP2,SPATA18,ACVR1C,BNIP3L,SLC35C1,POR,RAB2B,SH2D3C,MAPK13,F2RL1,FGD1,SEMA6B,RECQL,THEMIS2,PRKAA1,AKAP17A,TNFRSF19,TSPAN7,MESDC2,CALR,RALGPS2,VASN,PPP4R1,MSH2,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,GPR161,SOCS5,GFPT1,PRODH,CALM1,DCHS1,WHSC1,EPHA1,ANTXR1,PDE11A,PELI2,MATN2,PIAS2,ARAP1,APPL2,MPP2,CABIN1,IFIH1,EHD1,SPRED1,TCTN2,REPS2,THRA,NDRG1,RALBP1,BCL2L1,FLT3,DDR1,CYP39A1,ZFYVE9,EPS8L2,NOV,CCNA2,ACAP2,RALB,RNASEH2A,PDE4D,EPHB4,OSBPL7,TSPAN1,SULT2B1,MED30,SEMA3B,ATG4D,DOCK4,ATP1B1,RAD17,PYGO1,CBL,ASB13,ITPR3,ALCAM,FZD7,NGFRAP1,TSPAN18,PRKAR1A,PLSCR4,IGFBP6,DEPDC1,CENPI,EPS8,HERC5,PLD2,FBXO6,SPDL1,EFNB1,FGF19,ADGRB2,HLA-A,CKAP5,RASSF8,E2F7,GNB5,FUT8,CD9,ERBB3,CITED2,MSH6,FARP2,PDGFC,TGIF1,ZWINT,ALDH2,ARHGEF28,PAPD7,DIAPH2,YES1,FOS,TIMP3,FGFR2,RIN3,RYK,RABL6,LRRK1,FZD5,MELK,RGMA,CCNC,UGT8,FAF2,MAP1LC3B,TRIM68,HTR1D,ZFYVE16,EPCAM,RAB15,SIVA1,ASH2L,CTTN,IL1RAP,SP5,CYP1B1,CXXC5,CENPA,ITCH,USP18,ARHGDIB,GPRC5B,MADD,CAB39,NRGN,NR2C2,PCSK5,ARAP3,PPP1R12A,ETV5,ASB9,CALM3,TEC,DUSP5,SPP1,NOXA1,CES2,OCRL,COL6A1,PRKCI,BRAT1,NPTN,C10orf54,HLA-C,ZRANB1,CCDC88A,MDFI,ELK3,PDE5A,RHPN1,INSR,SH3BP4,RAB31,NXPH4,SHROOM2,JAK3,TOB1,COL16A1,RARG,DRD1,SORBS1,PDIA5,SOD2,IL27RA,MRAS,EXT2,ARTN,CYP4F11,KIF14,DIXDC1,NFKB2,CHP1,PTPRU,MRPS35,CD40,CDC25C,FANCE,CASP4,ARHGAP35,SOCS3,STAT6,SECTM1,TLE1,SPTBN5,RCAN2,ABCA1,GCLM,ARHGEF11,SHPRH,CIT,ARHGEF7,SERPINB9,TGFBR1,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,TOP2A,ADRBK1,BMP7,ZDHHC13,RPGR,MYO5A,WNT10B,RGCC,NDRG3,LEPR,CTSL,ARHGAP24,CD8A,CASP7,RND3,CTSV,RAP2C,DTX4,ARRB1,UACA,PLOD3,AHR,CD33,NGEF,IL15RA,ADD1,TRIM24,TRIM5,DNAJC3,SMARCAL1,FBXO2,XIAP,NRG2,IL18,MORF4L2,KIF26A,BARD1,CA8,PHF1,DAPK2,CALM2,TP73,ZYX,TGFBR3,RGS12,PSMD1,ARHGAP42,CYP2S1,KLF3,PIK3CD,SEMA3G,TNIP1,SPRTN,MYOM1,CYP4F3,PGF,DNM1L,LIMK1,MYLK,MAP3K11,SERPINB6,ARF6,GAB1,NUAK1,CYP2J2,SOX9,ZNRF3,MERTK,LMNA,FAM13B,STT3B,NCAM1,EPHX1,UFD1L,SALL4,STAT4,CALCRL,ILK,RHOB,STK17A,PTPRF,NCOA3,SEMA4D,HTT,ITPR1,OSMR,MDH1,ARPC2,NDE1,TRPC3,RPS6KA3,EGLN1,ARHGAP11A,PAPSS2,ACTR8,WDTC1,IL13RA1,NUF2,APC2,PRKACA,KTN1,TNFSF9,ZNF385B,CDS1,CCND1,SP100,DACT1,RTKN2,RAB27B,ARL4D,CDKN2D,RNF169,FZD4,NRBF2,RAB38,IRS2,SLC9A6,WWTR1,SIPA1L1,INPP4B,TRABD2A,RGS14,GEN1,ARNT,TNRC6C,NKX3-1,TAOK2,RASSF7,PDIA3,PKN1,GSTP1,ETS1,TIPRL,ICAM1,PDIA4,CAPN2,DTX3L,CXCL16,ANK1,IRAK1,MCF2L,FDXR,TMBIM6,ADAM15,MAPK11,WWP1,TMX1,S100A6,HCN3,AMOTL2,CTNNAL1,RAPGEF2,BCL9,GRIN1,NEURL1B,SKA1,TXK,KIAA0141,ACVRL1,NR1D2,HMGA1,CENPE,NUP37,USF2,FOXA1,MYL9,UNC93B1,SIGIRR,AGRN,EPHA4,CUL4B,NDC80,HDAC6,SDC1,PDGFB,PCNA,SHC3,DUSP10,TNFRSF18,MCTP1,EZR,ERP44,PRKRA,CDK1,PLEKHB1,RHEB,VCP,DPYSL3,OPTN,PLCH1,WIPI1,MAP2,PIK3C2B,CTNND1,PRKAA2,BMF,HLA-F,RACGAP1,DOCK11,DHRS3,IL18R1,CORO1B,BMP2,RB1,VASP,IGF1R,PAK2,MDFIC,PLCB2,PSMA5,CYP26B1,CORO2A,TCF7,EIF2AK1,IFIT3,MAPKAPK2,PVRL2,CSF1,ITGA7,LTBP2,IFI6,RNF146,UGP2,NF2,FOXM1,XYLT1,DGKA,ERBB2,CCDC68,RASGRP3,CYP26A1,CDK14,RAD23A,ATP6V0B,SRPX,PLCG2,EGLN3,SCN2A,DVL2,CTH,SIRT1,TIMP2,TCEB2,FIGNL1,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,RTN4RL1,PTK7,PSMD3,GSDMD,ADGRG1,CD63,DAP,SWI5,PSMD10,GABRG2,JAG2,CRABP2,PPP2R3A,BUB1,KLF9,CAMK2G,PSMB4,IFITM3,NR3C1,AMFR,PPARA,LITAF,PELI3,AKAP3,BCAR1,MAPK8IP1,PRDX4,CD83,FAT4,TWSG1,NAT1,NMI,PKD2,TBC1D4,NDFIP1,ACVR1,KLC2,GATA3,PLXNA1,CCNB1,SLC20A1,CENPN,NCS1,CTGF,ELMO2,IL31RA,ATRNL1,TFG,RCAN3,PBK,CASP9,AGO4,AURKB,PIF1,SAV1,ZFAND5,ULK2,SGPP1,AREG,TBX1,PLK2,NKD1,EIF4EBP2,UNC5B,TRAF5,DDX58,KLF2,HLA-E,DGKQ,NOTCH2,SLC1A3,ITGA3,PIK3AP1,CYR61,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,EEF1D,EPB41L5,DDB2,B9D2,MICB,ANO6,AMER1,CYFIP2,KDM3A,RASA1,FAS,DGKH,GABRD,PRKAG2,CSNK1G1,NR4A2,EFNA1,MAP3K5,IRF1,PLA2G4A,SLC2A4,TRIP10,S100A11,IQGAP1,RPS6KA1,EGR3,CD274,GNB2,APLP2,DOK4,CDKN1B,DAB2IP,IFIT1,LGMN,NR2C1,CDKN2AIP,DMTN,SLC11A2,PRKCQ,AKR1E2,EPHA10,FYN,PPP2R5A,JAK1,STK26,STAT1,KIAA1804,PPP1CB,RAB29,NRG1,SLC27A1,NR3C2,ATMIN,MRPS9,ARHGEF3,ARL4C,GPR180,TEAD3,LGALS3BP,RND1,PTEN,SGK3,PRC1,SLC44A2,ERCC2,MAP3K7,CNPY3,GFI1,SPRY2,TRIM62,NCOA2,RASGRF1,SHMT1,ARAP2,MPP1,PARP4,FURIN,GPLD1,RGS9,PRDX3,GRIN2D,GPER1,CPEB2,USP16,CASP3,LTBP1,KIF2C,DNER,CACNB4,KREMEN1,PTCHD4,SH3KBP1,ZCCHC12,DPYSL2,TSPAN6,AKR1B1,RAB20,KIF22,MYH14,PTPRE,RASGRP1,TDP1,TRIM8,SOD1,ROR1,ADRBK2,STK17B,EDNRA,CXXC4,MDK,NEIL1,ADIPOR1,RAP1GAP,PPP2R5D,PSMC1,GRN,LRRFIP2,ATP6V1E2,PHLPP1,CA2,LRRN2,DIAPH2-AS1,FNIP1,KNTC1,HP1BP3,OXR1,EGFR,BCAR3,GNAS,FECH,ONECUT1,TSC1,PLPP3,CDCA5,NFKBIA,RHOBTB2,YOD1,GAS2L1,SLC25A24,SPC25,IL15,PSME2,SLC2A8,ARHGEF16,SS18,SMO,TWIST1,GOT1,PDIA6,F2R,FRS3,MAP3K3,BAG4,KREMEN2,ERBB2IP,DUSP4,DOCK5,MAP3K6,CANT1,CYP2U1,PLXND1,SGOL1,LIFR,SORT1,JKAMP,LRP4,AES,NOTUM,IL17RB,ADORA1,BRD7,IQGAP3,RAB3B,ADAM17,CENPC,NR4A1,DEPDC4,GCLC,POLD3,HLA-B,DHRS2,UBE2D2,GEM,SOX8,ATP6V1C1,L1CAM |
| 1.069e-06 | -13.75 | MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | 114 | 37 | 17758 | 2588 |
FBLIM1,SLC25A24,NDRG1,FXYD3,PKP2,BLCAP,TSPAN17,KTN1,PSIP1,WEE1,SPP1,MLPH,GRHL1,SLC44A2,ERBB3,NFE2L3,PDGFC,PRSS23,TFAP2C,EZR,TCF7,ATP1B1,GALNT7,IDH1,SOX13,EDNRA,SFXN1,CD8A,PRKAG2,TJP3,KCNK1,RND3,NIPSNAP3A,FHL1,LSM14B,OCLN,PROM2 |
| 1.073e-06 | -13.75 | BIOPOLYMER_MODIFICATION | MSigDB lists | BIOPOLYMER_MODIFICATION | 643 | 138 | 17758 | 2588 |
TNK1,ACVR1,SSH1,RET,FBXO2,HDAC6,PICK1,DAPK2,CDKL5,P4HB,IL31RA,FUT1,DUSP10,PPP1CA,PTPRE,APOBEC3G,METAP2,NEK4,PTPN18,MARK1,RNF11,GALNT7,LOXL2,ICMT,STK17B,DOLPP1,LIMK1,MYLK,PPP2R4,MAP3K11,POMT1,PCSK5,PRKAA2,CDK17,PRKAA1,MERTK,TSPAN7,DUSP5,RABGGTA,B3GALNT1,IGF1R,PAK2,MAP3K9,DAPK1,TPST1,PRKG1,PRKCI,STT3B,PIM1,MYLIP,GAD1,CCDC88A,NAGPA,PIGC,DDB2,QSOX1,PTPRH,MGAT4B,STRADB,EIF2AK1,ILK,EGFR,NMT2,STK17A,MAPKAPK2,MMP15,TSC1,FNTA,INSR,AURKA,ALG2,JAK3,CTBP1,DMPK,NF2,HDAC11,TESK2,ERBB2,MAPK4,EPM2A,CCND1,PPME1,PLK4,RPN2,PHKA2,LOXL1,F2R,SEPHS1,MAP3K3,SIRT1,AKT1,COG2,PTPRU,PTPN9,DUSP4,CBL,MAP3K6,PTPRJ,STK38,STAT1,KIAA1804,MAPK12,DYRK3,PINK1,MAN1A2,TGFBR1,POMGNT1,TRIB2,SBF1,PKN1,PPP2R3A,WWP2,FUT2,CDK16,PTEN,MGAT4A,FUT8,SGK3,SGK1,WWP1,ERBB3,SLC35A1,GCNT1,AMFR,FURIN,PARP4,YES1,FOS,BCL10,TXK,PRDX4,PLOD2,ACVRL1,NR4A3,PLOD3,CD81,UBE2C,HIPK3 |
| 1.089e-06 | -13.73 | HORIUCHI_WTAP_TARGETS_UP | MSigDB lists | HORIUCHI_WTAP_TARGETS_UP | 284 | 72 | 17758 | 2588 |
MYL9,SSH1,HOXB7,IL15,SOD2,ITPR2,SH3KBP1,CHST2,SIPA1L2,ENTPD4,KHNYN,ANKRD12,LAMP3,ATL1,PCGF5,SPATA18,OSTM1,HTATIP2,SLC11A2,DUSP4,PTGFRN,TCN2,TAPBP,ANKRD6,BHLHB9,PIK3C2B,TANC2,GLCCI1,ABCA1,CPPED1,GLIS3,SERPINE2,ALDH6A1,DNAJB2,SDC4,ASAH1,TRIB2,BEX2,DUSP5,ICAM1,LGALS3BP,MESDC2,CD109,DIRAS3,CXCL16,OPN3,ACTA2,LIMCH1,MYLIP,LRIF1,GFPT1,NR3C1,PARD3B,DUSP23,LRRC1,IFIT3,PCTP,ENDOD1,IL1R1,NUDT16,CASP7,CTNS,NR1D2,H1F0,PRCP,CSF1,ITPR1,ERAP1,ARRB1,OSMR,PER3,IFIH1 |
| 1.091e-06 | -13.73 | epithelial tube morphogenesis | biological process | GO:0060562 | 303 | 77 | 16441 | 2455 |
ACVR1,GRHL2,LGR4,ST14,EPHA4,RET,GATA3,PRKACA,STIL,SETDB2,CTNNB1,NPNT,LMO4,SMO,DLG1,TWIST1,TACSTD2,PPP1CA,ETV4,DVL2,TFAP2C,DAG1,EDNRA,IRX3,ARHGAP35,AREG,SHROOM3,PTK7,PLXND1,COBL,CTHRC1,NKX3-1,TMTC3,SDC4,CCM2,SOX9,RAB23,CTSZ,NCKAP1,FZD6,GBX2,CTNNBIP1,BMP2,VASP,GPC3,MEGF8,BMP7,BAX,MAP3K7,WNT3A,NTN1,SLC12A2,SPRY2,HES1,TGIF1,SALL4,FMN1,DCHS1,PRICKLE1,SCRIB,KIF20B,NPHP3,ILK,BCL10,TSC1,NCOA3,FAT4,FGFR2,ACVRL1,CSF1,SPINT2,PKD2,SOX8,OSR1,RARG,FOXA1,ADAMTS16 |
| 1.097e-06 | -13.72 | PROTEIN_KINASE_ST | prosite domains | PS00108 | 309 | 79 | 11866 | 1802 |
ACVR1,CAMKK1,RPS6KA1,MAPK4,CAMK1D,GRK6,PRKACA,CDK14,DAPK2,WEE1,RPS6KA2,CDKL5,PASK,STK35,NEK4,PLK1,MARK1,AKT1,RIPK2,ACVR1C,PBK,PRKCQ,PKMYT1,AURKB,MAP3K6,STK17B,ADRBK2,CDK1,ULK2,CDK19,PLK2,STK38,MYLK,KIAA1804,MAP3K11,PRKAA2,TAOK2,DYRK3,PINK1,CDK17,NUAK1,CIT,PRKAA1,TGFBR1,PKN1,BMP2K,ADRBK1,IRAK1,CDK16,PAK2,PRKCI,SGK3,NEK2,MAP3K9,PRKG1,DAPK1,SGK1,BUB1,PIM1,MAP3K7,MAPK7,MAST4,PHKG2,CAMK2G,MAPKAPK3,EIF2AK1,PIM3,PDIK1L,STK17A,MAPKAPK2,ACVRL1,CSNK1G1,AURKA,CDK18,MAP3K5,HIPK3,MELK,RPS6KA3,DMPK |
| 1.098e-06 | -13.72 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | 184 | 52 | 17758 | 2588 |
CD99,GCLM,IL15,VANGL1,CAST,NDRG1,MCTP2,EFHD2,BCL2L1,GALM,PLA2G16,WWP2,CAPN2,TGFBR3,CTSC,SLC16A6,RGS3,OSBPL3,PLCG2,PPP4R1,ABCA2,MDFIC,RASGEF1A,DLG3,GFI1,MYBL1,C12orf75,APOBEC3G,SYTL3,KIAA1841,SNTB2,S100A4,ITCH,SYNE2,UTRN,RUNX3,PIF1,BLVRA,FAS,OPTN,ARHGAP35,GALNT3,FYN,PTPRJ,WIPI1,SERPINI1,MAP3K5,ARF6,GLCCI1,SLC27A3,CPEB2,STARD3NL |
| 1.098e-06 | -13.72 | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | MSigDB lists | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | 184 | 52 | 17758 | 2588 |
REPS2,DLGAP5,FOXM1,ATP8A1,BLVRB,PTTG1,EPS8,ASB9,ABCG2,KIF23,HMGN3,KIF2C,TRIB2,CCNB1,DHRS3,HDAC9,CDKN2C,PAK6,ANK1,RPS6KA2,NUP210,CCNA2,GNB5,RANBP1,SORL1,TUBG1,CKS1B,TSPAN13,MDFIC,ITM2C,TRAK2,HMMR,CORO2A,CDC20,CCNF,CYFIP2,CDC25C,ENDOD1,BANK1,PROM1,FAAH,INPP4B,CSGALNACT1,ABCB1,EGFL7,SERPINB6,SERPINI1,PLXND1,WDR62,CCNB2,UBE2C,NXT2 |
| 1.114e-06 | -13.71 | CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP | MSigDB lists | CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP | 34 | 17 | 17758 | 2588 |
LASP1,SLC37A1,AKT1,BIK,CLSTN1,CYB561,DDR1,POR,ARHGEF16,CORO1B,MMP15,TJP3,CDK16,PVRL2,DUSP10,ADIPOR1,GPX4 |
| 1.121e-06 | -13.70 | adenoid_cystic_carcinoma | COSMIC cancer mutations | adenoid_cystic_carcinoma | 1159 | 226 | 17775 | 2585 |
TNK1,ACVR1,HSPG2,SLC25A13,RET,PDGFRL,BAIAP3,SPTB,SLC9A7,CALM2,TYMP,WEE1,SIPA1L2,RPS6KA2,PQLC2,MUC4,CTNNB1,PAPSS1,DLG1,PIK3CA,ANKRD12,SEMA3G,ARNT2,ACOX2,PIK3CD,TFG,MYBL1,ERAP2,ZNF462,NEK4,SMARCA2,TNIP1,LAP3,SERTAD4,PBK,AURKB,PRKRA,IDH1,CLCN2,GINS4,LCP1,FAM177A1,FASTKD1,MAP2,PLK2,ATP7B,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,TANC2,HOXC13,MRC2,RUNX2,CDK17,ZNF395,CHCHD7,NOTCH2,DOCK11,RB1,IGF1R,PFKL,CD22,FRAS1,FCHO1,DAPK1,PRKCI,PRKG1,OPN3,MAP3K9,FNIP1,USP1,USP38,KNTC1,PIM1,CACNA1D,CNGA1,PIKFYVE,MAPK7,ALDH3A2,MPHOSPH9,USP31,ADCK3,PTPRH,PIP4K2C,SPATA13,BTN3A2,KIF20B,EIF2AK1,PDK3,NFIB,EGFR,MAPKAPK2,TSC1,SEMA4D,DCK,NAB2,FGD6,NXPH4,AURKA,DYSF,MAP3K5,JAK3,CDAN1,TOB1,RPS6KA3,ADAMTS16,DMPK,MFSD3,SLC25A24,CAPN12,TRIP10,CAST,RPS6KA1,THRA,DGKA,TP53,ETNK1,ERBB2,GRK6,PRKACA,FLT3,DDR1,APPBP2,CDK14,MUC16,SP100,LHX6,TNPO2,BRI3,EPHB4,DLG3,LRP11,MYT1,SCYL3,FRS3,SEPHS1,MYO5B,MAP3K3,RFK,AKT1,COG2,CAPN6,SYNE2,UTRN,ERBB2IP,ATP1B1,TANC1,MAP3K6,NFIX,DUOX1,FYN,PTPRJ,JAK1,CDK19,PTK7,STK38,AXL,OVOL1,IRF7,KLF5,PDXK,AIFM3,ABCA1,LIFR,PRKAR1A,MAPK12,PINK1,TNRC6C,CENPI,GNE,FAM134A,NOTUM,SEPP1,TSPAN17,NEO1,TMEM63A,KIF5B,DIRAS3,FOXP2,ANK1,CEP97,ITGB8,IRAK1,CDK16,PTEN,MGAT4A,TFAP2A,CKS1B,SGK1,MAPK11,IGFBP2,ERBB3,MAP3K7,SYK,CAMK2G,SUN2,ARHGEF28,CASK,B3GNT2,ARAP2,ELOVL3,PIK3R1,ZKSCAN2,AK4,MAML2,COL7A1,YES1,RNPEP,MAPK8IP1,DDX23,DCAF10,BTG1,FAT4,FGFR2,CCDC6,PKD2,CENPE,ZMIZ1,OSR1,TBC1D4,ESPL1,L1CAM,MELK |
| 1.129e-06 | -13.69 | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | 189 | 53 | 17758 | 2588 |
GRN,PINK1,LGALS3,ST14,TBC1D1,HLA-E,HLA-F,TSC22D3,CTSB,BTN3A1,CTSZ,SLC1A3,SIRPA,SCML1,SGPL1,MARCH8,TYMP,MGAT1,METTL7A,TSPAN6,DACT1,BCL6,FAM63A,RAB20,LIMCH1,HLA-C,PTPRE,CKAP4,LAMP3,VPS11,PDGFC,ARAP2,TIMP2,RIPK2,ADCK3,VAMP3,CBX6,SLC11A2,SRSF5,NPC2,CD83,LDLRAP1,PELI2,SLC2A6,WDR19,ARAP1,RYK,ARRB1,CTSA,PLXND1,PLOD3,CD81,SLC31A2 |
| 1.129e-06 | -13.69 | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 189 | 53 | 17758 | 2588 |
DDX58,PARP12,AGRN,IL15RA,TRIM5,HLA-E,CYP2J2,TAP1,HERC5,RASGRP3,PDGFRL,SAMD9,HERC6,BARD1,DUSP5,LGALS3BP,RABGGTA,SPP1,NOV,SP100,TRANK1,TMEM62,DRAM1,BCL6,TRIM21,IFIT1,OAS3,LAMP3,MX1,RIPK2,PLSCR1,IFITM3,LAP3,RAPGEF2,USP18,LYRM1,AK4,IFIT3,PSMA4,CASP4,PRDX4,SOCS3,ETS2,C19orf66,NMI,SLC2A6,STAT1,TDRD7,IRF7,IFIH1,IFI6,APOL2,IRF1 |
| 1.129e-06 | -13.69 | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | 189 | 53 | 17758 | 2588 |
CDK17,PLSCR4,FRMD4A,NFKBIE,FRMD6,SOD2,KCTD12,GDF15,CCNL1,PHLDA1,STIL,TNFSF9,DUSP5,ICAM1,MXD1,IER3,BMP2,OTUD1,TNS3,SGK1,RAB20,PIM1,CITED2,TIPARP,SPRY2,C9orf72,STK35,DUSP1,TGIF1,RIPK2,PLSCR1,PLAUR,FURIN,FAM133B,DUSP4,ZFAND5,RNF19B,FOS,CDK5R1,CD83,BCL10,MAPKAPK2,HLA-B,PTGS2,UAP1,PLK2,GEM,FZD5,TOB1,KLF7,USP16,IRF1,EHD1 |
| 1.129e-06 | -13.69 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | 189 | 53 | 17758 | 2588 |
GRN,SORT1,TXN,RUNX2,CRYM,ST14,NDRG1,HEXB,HERC5,TEX2,MGST2,NUCB2,SLC20A1,GSTP1,FLT3,IL18R1,DUSP5,BCAP31,ICAM1,RAB15,CTSC,SIVA1,MGAT4A,RRBP1,CST3,DAPK1,H2AFY,MDFIC,AHCY,MARCH2,EGLN3,PTPRE,GFI1,ITM2C,NAGA,SEC61B,ALDH2,MAPKAPK3,DSTN,CBX6,LHFPL2,MYL12A,MAPKAPK2,SCARB2,SERTAD2,DCK,CORO1C,SH3BP4,IRF7,TMEM8B,FHL1,TBC1D4,RPS6KA3 |
| 1.129e-06 | -13.69 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | 189 | 53 | 17758 | 2588 |
CDS2,PACSIN2,AVPI1,IGFBP6,CD63,TBC1D1,PSME2,CTSB,TMEM41B,HLA-F,FBXO2,DSE,SPR,BCAP31,SIRPA,ARHGEF10L,GNS,SPP1,APLP2,BHLHE41,GALNS,TMEM51,CD9,SGK1,PTPRE,SPRY2,SYK,PHKG2,GM2A,DVL2,CKAP4,CYP1B1,DOCK4,QSOX1,RIPK2,LAP3,SAT1,VAMP3,CDA,PYGL,TNS1,NPC2,SAV1,LHFPL2,ATP1A1,CORO1C,PLK2,PLXND1,ARSB,SLC27A3,CD81,NR3C2,IFI6 |
| 1.136e-06 | -13.69 | acute_lymphoblastic_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_leukaemia | 2279 | 408 | 17775 | 2585 |
HECA,GAA,ACVR1,LGR4,HSPG2,GRIK2,TSC22D3,RET,TRAPPC8,PSME1,BAIAP3,CAMK1D,PLXNA1,SEPT4,SLC20A1,PAK6,DAPK2,WEE1,ZYX,MUC4,CTGF,ZFP36,PPP1R16A,FOSB,AOX1,STEAP2,PIK3CA,PPP1CA,MARCH2,PACSIN1,TIPARP,ANKRD9,NEK4,KIFC2,ACVR1C,PBK,SLC35C1,TNS1,AURKB,SAV1,SPNS3,COL12A1,ULK2,PLK2,ATP7B,LIMK1,MYLK,FAM114A1,MAP3K11,BMP1,DHTKD1,MAPK13,RNASEL,WBSCR27,STARD13,CDK17,INPPL1,FRMD4A,PRKAA1,STRN4,KIF23,NOTCH2,APBA1,MERTK,BMP2K,CALR,FLII,FRY,PIK3AP1,ZIC5,NEK2,DAPK1,PRKG1,ADCK2,MAP3K9,ALPK1,FAM84B,CACNA1D,MAPK7,KANK3,KCTD3,PHKG2,GPR161,EPB41L5,ADCK3,PIP4K2C,MYBL2,KCTD20,WHSC1,RHOB,STK17A,MMP15,CACHD1,SCARB2,PLEKHH2,TJP3,SLC4A4,HTT,AURKA,CDK18,DRP2,MAP3K5,PLIN3,PER3,NRBP1,RPS6KA3,ADAMTS16,DMPK,PKD1L2,DOCK9,SPRED1,TCF25,SLC2A4,NLRX1,TMEM217,ST14,GALNT12,RPS6KA1,IQGAP1,ETNK1,PKP2,TESK2,FAM78A,GRK6,PRKACA,FLT3,DDR1,MOCS1,SLC25A35,MUC16,DAB2IP,EPHB4,MYO5B,COL6A2,RIPK2,COG2,PFKFB2,SEPT6,SYNE2,KIF1C,SLC11A2,PRKCQ,PKMYT1,CBL,ITPR3,ZNF469,PRDM11,EPHA10,PEX5,FYN,PPP2R5A,POPDC3,CCNB3,JAK1,ACAD10,SHROOM3,CDK19,AXL,KIAA1804,PNPLA6,SLC27A1,MLKL,RGS14,B4GALT3,SLC25A30,NR3C2,COBL,MAPK12,DENND5B,MRPS9,GALK1,ANKRD13D,TAOK2,TRAF2,PKN1,DNAH3,TSPAN17,ICAM1,SIX4,SNTA1,TMEM87B,FUT2,IRAK1,SLC27A6,FAM160A2,PTEN,KNDC1,TUBGCP6,SGK3,ADAM15,SLC44A2,MAPK11,ERBB3,RAG1,MAP3K7,ITM2C,TPCN1,MSH6,RASGRF1,CASK,B3GNT2,PIK3R1,CXorf57,PLEKHA7,FURIN,YES1,KIF11,TXK,GPLD1,CRTC2,BTG1,FGFR2,ACVRL1,PGM2L1,ESPL1,MELK,OCLN,TLL2,LTBP1,TNK1,CPT2,CAMKK1,EPHA4,FHDC1,TAF6L,MGAT5B,GALM,BTG3,RPS6KA2,CTNNB1,P4HB,CDKL5,SLC44A1,ANKFN1,DLG1,KIF22,TLN2,IL1RAP,STK35,PLK1,THRB,ATL1,CD55,MARK1,ING1,CELSR2,FOPNL,CR2,ARFRP1,ROR1,ESYT1,IDH1,SESN1,ADRBK2,STK17B,TRUB1,TRIM9,PI4K2B,TBC1D17,ZNF114,KCNMB4,HPSE,WIPI1,MAP2,P4HA2,MADD,CTNND1,SP6,TC2N,CAPN1,PRKAA2,CD99,ZNF395,PEX6,ATP6V1E2,ADCK5,DOCK11,LYSMD4,SPP1,RB1,DAZAP1,IGF1R,PFKL,GATA2,FRAS1,ICAM5,PRKCI,BRAT1,PIM1,TMEM8A,MPHOSPH9,CCDC88A,SNX7,HP1BP3,USP31,TESK1,PARD3B,STRADB,TCF7,EIF2AK1,PDK3,PDIK1L,C3orf58,RANBP9,EGFR,PRX,GNAS,MAPKAPK2,INSR,ITGA7,PHLPP2,CDCA5,NLRC5,ALPK3,LTBP2,SHROOM2,JAK3,TOB1,CTBP1,FAM45A,LZTFL1,KCNAB3,NF2,IL15,TP53,COL18A1,ERBB2,TDRKH,FAM198B,ZMYND10,LPIN3,MICALL2,PCBP1,CDK14,TACC2,PLK4,CDH3,F2R,HSPA2,SCYL3,FRS3,CTH,MAP3K3,AKT1,TMTC2,MAP3K6,PAFAH1B3,PTK7,STK38,PSMD3,STAT6,ANXA9,PLXND1,ZBTB6,REEP4,BIN1,PINK1,DYRK3,GOLIM4,CDH22,ENO2,TRAPPC10,MACC1,TAB3,SERPINB9,HAL,PSMD10,TGFBR1,COL4A5,NOTUM,JAG2,TRIB2,SBF1,AIP,HMGXB4,NRP2,IRF2BPL,CEP97,ADRBK1,CDK16,TFAP2A,ACTA2,SGK1,ABCD1,BUB1,SYK,CAMK2G,FAM134C,IGDCC4,P2RX4,NFE2L3,NR3C1,OGDHL,COL7A1,AKAP3,BCL10,ARHGAP24,FAT4,SERPINA1,C2orf70,TMC5,NETO2,UACA,HIPK3,L1CAM,SAT2,RAB3IL1,DIS3L |
| 1.136e-06 | -13.69 | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | MSigDB lists | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | 305 | 76 | 17758 | 2588 |
LAMP1,SIGIRR,TMX4,HEXB,PDIA5,SOD2,IL18,TEX2,CCNL1,TSEN34,APLP2,ZFP36,ATP13A3,MITF,AKR1B1,RAB20,SNX10,TUBA4A,CPD,PPIF,TIMP2,MCTP1,CD55,ZFAND5,STK17B,MAN2A2,FYN,MPRIP,STAT1,NRG1,PDXK,GLA,RPL22,LTA4H,F2RL1,CHPT1,PINK1,PACSIN2,LGALS3,CDKN1C,ZNF395,TBC1D1,CTSB,HLA-E,ASAH1,SELL,GTF3A,NOTCH2,ARHGEF40,HDAC9,GNS,MDM1,BHLHE41,SLC16A6,SGK1,SORL1,KLF9,CTSD,CNPY3,SLC16A5,ALDH3A2,FAH,SUN2,PLSCR1,SNTB1,SPTLC2,RASGRP2,STK17A,SCARB2,ETS2,ITPR1,CCDC69,ARFGAP3,NR4A2,PLOD3,IFI6 |
| 1.138e-06 | -13.69 | ribonucleoside binding | molecular function | GO:0032549 | 1798 | 337 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,KIF13A,PIF1,AURKB,RAB2B,ARF4,ULK2,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,STK17A,DHX32,DGKH,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,TRANK1,RALB,FICD,EPHB4,ACSL4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,GALK1,HSP90B1,TAOK2,ATP9A,ARL4C,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,OPLAH,PCCB,CASK,UBE2A,AK4,PIM3,YES1,KIF11,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,TNK1,NMRK1,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PAPSS1,PSMC2,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,ADRBK2,STK17B,CDK1,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,PSMC1,RRAGD,PRKAA2,LMTK3,RUNX2,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ABCC1,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,ATP1A1,IDE,STK38,PTK7,XRCC3,ABCA1,DYRK3,PINK1,TOR4A,CIT,SHPRH,GNAL,GNE,ERCC6L,TGFBR1,KIF5B,TOP2A,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,MYO5A,ATP2B1,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,RAP2C,UBE2D2,GEM,UBE2C,HIPK3,ABCG1 |
| 1.152e-06 | -13.67 | lytic vacuole | cellular component | GO:0000323 | 517 | 116 | 17570 | 2579 |
DOC2A,LAMP1,UNC93B1,GAA,AGRN,HSPG2,TRIP10,SLC2A8,HEXB,SDC1,GNB2,EPDR1,ABCD4,NAPG,PQLC2,AP1M2,RDH14,ABCA2,AKR1B1,SNX16,GOT1,ECE1,TINAGL1,PIK3CD,MARCH2,TSPAN1,LGMN,NAGA,S100A13,TMEM9,TMBIM1,GM2A,RASGRP1,LAMP3,LAMP2,VPS11,SOD1,EVA1A,OSTM1,AP5M1,SLC11A2,SLC17A5,RNF19B,TCN2,RHEB,ATP13A2,ENPP1,HPSE,WDR11,GLA,CAPN1,ANXA11,RRAGD,STARD3NL,SORT1,CD63,TMEM55B,CTSB,SDC4,FLOT1,ASAH1,CTSZ,TMEM63A,M6PR,MARCH8,CAPN2,GNS,CTSC,ARSG,ZNRF2,GATA2,VASN,GPC3,CST3,GALNS,COL6A1,DRAM1,PCYOX1,PLEKHF1,SLC44A2,CTSD,TMEM8A,ITM2C,C9orf72,TPCN1,MYO5A,P2RX4,MMD,IFITM3,GUSB,LITAF,CALCRL,GGH,NPC2,GNA11,C18orf8,STX3,USP6,BCL10,GPLD1,FUCA1,CTSL,NAAA,SCARB2,CTNS,SYT7,PRCP,CTSV,PLA2G15,NR4A3,ARRB1,GLB1,CTSA,PLD1,ATP6V1C1,ARSB |
| 1.152e-06 | -13.67 | lysosome | cellular component | GO:0005764 | 517 | 116 | 17570 | 2579 |
DOC2A,LAMP1,UNC93B1,GAA,AGRN,HSPG2,TRIP10,SLC2A8,HEXB,SDC1,GNB2,EPDR1,ABCD4,NAPG,PQLC2,AP1M2,RDH14,ABCA2,AKR1B1,SNX16,GOT1,ECE1,PIK3CD,TINAGL1,MARCH2,TSPAN1,LGMN,NAGA,S100A13,TMEM9,TMBIM1,GM2A,RASGRP1,LAMP3,LAMP2,VPS11,SOD1,EVA1A,OSTM1,AP5M1,SLC11A2,SLC17A5,RNF19B,TCN2,RHEB,ATP13A2,ENPP1,HPSE,WDR11,GLA,CAPN1,ANXA11,RRAGD,STARD3NL,SORT1,CD63,TMEM55B,CTSB,SDC4,FLOT1,ASAH1,CTSZ,TMEM63A,M6PR,MARCH8,CAPN2,GNS,CTSC,ARSG,ZNRF2,GATA2,VASN,GPC3,CST3,GALNS,COL6A1,DRAM1,PCYOX1,PLEKHF1,SLC44A2,CTSD,TMEM8A,ITM2C,C9orf72,TPCN1,MYO5A,P2RX4,MMD,IFITM3,GUSB,LITAF,CALCRL,GGH,NPC2,GNA11,C18orf8,STX3,USP6,BCL10,GPLD1,FUCA1,CTSL,NAAA,SCARB2,CTNS,SYT7,PRCP,CTSV,PLA2G15,NR4A3,ARRB1,GLB1,CTSA,PLD1,ATP6V1C1,ARSB |
| 1.155e-06 | -13.67 | negative regulation of cellular protein metabolic process | biological process | GO:0032269 | 957 | 196 | 16441 | 2455 |
CASP3,PPP4R4,ST13,IBTK,DNAJC3,XIAP,NDRG2,PSME1,CCNB1,HDAC6,RIC1,PHF1,TP73,CALM2,CDKN2C,PSMD1,CTNNB1,ZFP36,RGS3,PSMC2,DLG1,DUSP10,CRY2,PLK1,CD55,TNIP1,ITCH,PBK,EZR,AGO4,PRKAR2B,POR,PIAS3,ENPP1,CAMK2N2,LIMK1,TRAF3IP1,PPP2R4,SERPINB6,EIF4EBP2,SERPINI1,SPRY4,HSPB1,F2RL1,PSMC1,LMTK3,CDKN1C,SERPINE2,DNAJB2,UBASH3B,PDCL,RAB23,PSMD7,CALM3,FBLN1,DUSP5,SH3RF2,MECOM,TFAP4,CALR,RB1,TIMP1,IGF1R,PAIP2B,FBXO7,PAK2,DAPK1,FNIP1,SORL1,PSMA5,SOCS5,CALM1,HMG20B,EIF2AK1,EPHA1,ILK,KDM3A,PSMA4,RANBP9,FAS,TSC1,PRKAG2,SEMA4D,HTT,PLPP3,STK39,SERPINB1,TOB1,IFI6,CTBP1,RPS6KA3,XDH,DRD1,SPRED1,NF2,FOXM1,RPS6KA1,PSME2,CAST,PTTG1,CTDSPL,TP53,P2RX7,PATL2,SYTL2,PER2,CD46,APLP2,SVBP,DACT1,CDKN1B,DAB2IP,TWIST1,PDE4D,DLG3,CDKN2D,CTDSP2,CHP1,SIRT1,CAMSAP3,TIMP2,BAG4,AKT1,DMTN,CDC20,PKMYT1,DUSP4,SNX12,DAG1,C3orf33,SOCS3,DNAJC10,FYN,IDE,PTPRJ,STK38,CORO1C,PSMD3,WWTR1,RGS14,PRKAR1A,CTDSP1,ARFGEF3,PINK1,FARP1,TNRC6C,CPEB4,TRAF2,SERPINB9,PSMD10,PKN1,TRIB2,GSTP1,TIPRL,SH2D4A,CD109,SNTA1,PTEN,BMP7,GPC3,CST3,BAX,H2AFY,TRIM21,BUB1,HEXIM2,RAG1,CNOT6L,SPRY2,CRTAP,DUSP1,PSMB4,PLAUR,GCLC,FURIN,COL7A1,FXR2,MAPK8IP1,LEMD2,CDK5RAP1,CNOT2,BANK1,TIMP3,SWAP70,SERPINA1,PRDX3,SPINT2,SERPINB5,ARRB1,GPER1,LRRK1,UBE2C,CPEB2,HIPK3,PKIA,JARID2 |
| 1.156e-06 | -13.67 | GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN | 194 | 54 | 17758 | 2588 |
CCDC109B,PARP12,NFKBIE,IL15RA,IL15,PSME2,HLA-E,TAP1,CUL1,HERC6,PRRG4,RAD23A,CDS1,RCN1,TYMP,RALB,AIM1,SRP54,LRIF1,ETV7,ERAP2,MX1,CDKN2AIP,ARAP2,PLSCR1,RFK,LAP3,DENND1B,SNTB2,RAPGEF2,PLEKHO1,C15orf39,CD40,PSMA4,CASP4,BCL10,BCAR3,LRRC42,NCOA3,FNTA,CASP7,STK38,NMI,PRPS2,SECTM1,STAT1,NOD2,TDRD7,GRIN2D,IRF7,IFIH1,ISOC1,APOL2,MELK |
| 1.156e-06 | -13.67 | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | 194 | 54 | 17758 | 2588 |
CASP3,SPC25,ARMCX3,ENO2,DEPDC1,DLGAP5,FOXM1,RASA2,MCTP2,PTTG1,KIF23,RACGAP1,MORF4L2,NANS,CCNB1,FANCI,SAC3D1,TNS3,ADCK2,TUBG1,SRP54,MANF,LGMN,CTSD,SEPHS1,METAP2,PPIF,KIF20A,CTNNAL1,ASPM,PBK,SNTB2,CDC20,AURKB,ITPR3,KIF11,SKA1,DCP2,BCAR3,FUCA1,RAB11FIP1,PKD2,LRRK1,CENPE,HMGA1,PLIN3,ARPC2,NCAPG2,TBC1D4,UBE2C,CBX5,CCNB2,ESPL1,MELK |
| 1.156e-06 | -13.67 | GSE3982_NKCELL_VS_TH1_DN | MSigDB lists | GSE3982_NKCELL_VS_TH1_DN | 194 | 54 | 17758 | 2588 |
ANXA3,GCLM,ST13,IL15RA,DEPDC1,NQO1,PTTG1,KIF2C,ECI1,ICAM1,UHRF1BP1L,CKAP5,KIF5B,TNS3,OXCT1,NEK2,MSH2,CKS1B,TUBG1,TSPAN13,KLF9,MANF,OAS3,SMYD5,HSPA2,MYO5A,CKS2,CENPA,C3orf52,WHSC1,KIF20B,GLO1,GTF2A2,POLD3,SKA1,KIF11,STEAP1,GINS4,PRIM1,SFXN1,SLCO4A1,RBM47,TWSG1,FAM3C,AURKA,KPNA2,PDXK,NUP37,NCAPG2,UBE2C,CCNB2,E2F8,ESPL1,ACOT7 |
| 1.156e-06 | -13.67 | GSE22886_NAIVE_BCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_DC_DN | 194 | 54 | 17758 | 2588 |
GAA,PINK1,EPAS1,CD63,MRPS15,HEBP1,DCAF7,EFHD2,MGST2,DSE,VASH1,SIRPA,GNS,PSMD1,TM9SF2,MGAT1,SLC16A6,MITF,TFG,ETHE1,CITED2,TIAM1,CCDC88A,KDELR1,LAMP2,PPIF,DOCK4,SOAT1,PCCB,MAPKAPK3,GCLC,DENND1B,RAPGEF2,VAMP3,BLVRA,ATP1B1,VCP,ABR,GABARAPL1,RBM47,RCBTB2,DNM1L,ARAP1,MAOA,PLXND1,GLA,AKIP1,PLIN3,ZMIZ1,SLC31A2,NRGN,PSMC1,RTN3,ISOC1 |
| 1.163e-06 | -13.66 | MORI_LARGE_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | MORI_LARGE_PRE_BII_LYMPHOCYTE_UP | 84 | 30 | 17758 | 2588 |
HMMR,CENPA,TXN,TUBB4B,CDC20,CDCA3,MYBL2,KIF23,RACGAP1,CCNB1,H2AFV,CDK1,PRDX4,TOP2A,CDKN2C,IDE,CCNA2,CDCA5,PRC1,AURKA,CKS1B,KPNA2,KIF22,CENPE,CCNB2,PSMC1,E2F8,MELK,SMC4,RAD21 |
| 1.167e-06 | -13.66 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 300 | 75 | 17758 | 2588 |
LTBP1,SPRED1,KIAA1462,SLC25A13,CTDSPL,PDIA5,TDRKH,KCTD12,SEPT4,NUDT12,SDC1,KIAA1147,PER2,CCND1,RCN1,SUSD2,TGFBR3,RALB,TSPAN6,LMO4,IL31RA,SMO,CAPG,PTPN18,SLC39A8,SEPT6,CCBL2,GALNT7,CBL,LHFPL2,LCP1,CMTM7,MAN2A2,FYN,HLF,SLC25A4,AGPAT2,HOXA9,ZNF704,MAOA,PDXK,TTC8,MPZL1,SELL,PM20D2,TRIB2,C11orf95,RSAD1,SGPL1,SYDE2,TNS3,KIAA0895,OXCT1,RALGPS2,CTSC,H2AFY,SYK,SOCS5,SHMT1,MMD,NR3C1,PDE5A,GGH,RUNX3,CYFIP2,POLD3,H1F0,ITPR1,NLRC5,CCDC69,EGFL7,HOOK1,CD81,ACOT7,DOCK9 |
| 1.186e-06 | -13.65 | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | MSigDB lists | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | 259 | 67 | 17758 | 2588 |
KLK10,CAST,GALNT12,BLCAP,SNN,HDAC6,DPP8,PHLDA1,SNX9,MXD1,DAPK2,APLP2,CPNE2,RALB,KLF3,ALDH1A3,ATP13A3,DLG1,TINAGL1,TIPARP,GM2A,MYO5B,TMEM43,AGPS,UTRN,IRS2,PTGS2,SHROOM3,PLK2,RAB11FIP1,NRG1,CTNND1,SERPINB6,RAP1GAP,ARNT,CMTM4,FBLIM1,CPEB4,ITGA6,UBASH3B,DAP,RUSC2,EPS8,CRABP2,LGALS3BP,KIF5B,UBE2Q2,FLRT3,KCNN4,CCDC88A,ABCC1,HMMR,ARAP2,FMN1,FOS,RANBP9,BCAR3,MAGED2,SEMA4D,CLIP4,YOD1,PLD1,HOOK1,HIPK3,LRRC57,ABCG1,XDH |
| 1.211e-06 | -13.62 | KEGG_LYSOSOME | MSigDB lists | KEGG_LYSOSOME | 119 | 38 | 17758 | 2588 |
LAMP1,GAA,SORT1,CD63,GGA1,CTSB,HEXB,ASAH1,CTSZ,M6PR,GNS,ATP6V0B,ENTPD4,AP1M2,ARSG,CTSC,GALNS,ABCA2,LGMN,CTSD,NAGA,GM2A,LAMP3,NAGPA,LAMP2,GUSB,SLC11A2,NPC2,SLC17A5,FUCA1,SCARB2,CTNS,GNPTAB,PLA2G15,GLB1,CTSA,GLA,ARSB |
| 1.213e-06 | -13.62 | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | MSigDB lists | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | 417 | 97 | 17758 | 2588 |
ARHGAP11A,CCNE2,UGT8,FOXM1,GNPDA1,KIF2C,CCNB1,HDAC6,BARD1,ERP29,STIL,MNS1,WEE1,CCNA2,NUP210,IMPAD1,LMAN2L,KIF14,PASK,PLK4,RTKN2,HYLS1,ESPN,LRP11,FAR1,TMEM200B,PLK1,PSRC1,CENPA,FIGNL1,SYNE2,CKAP2L,NUSAP1,CDCA2,AURKB,PKMYT1,CCNF,LHFPL2,ADRBK2,ARHGEF26,MSL1,DNM1L,TSPAN18,KIAA1804,SH3GLB2,CANT1,MLKL,B4GALT3,REEP4,RAP1GAP,GEN1,NRGN,DENND5B,SLC16A14,SHPRH,FLOT1,GPSM2,FAM81A,PSIP1,PDXDC1,PRRG4,PARM1,M6PR,WWP2,RAVER2,OXCT1,CENPJ,LYPD6,PPP4R1,SLC35B4,ADCK2,NEK2,TAGLN2,FAR2,CNPY3,MPHOSPH9,MED22,HCN3,SUN2,SHMT1,TEF,MYBL2,WHSC1,KIF20B,RAB3IP,POLD3,BORA,KIF11,SKA1,C3orf58,ZMYND19,C1orf21,RAB31,AURKA,CENPE,HOOK1,MELK |
| 1.230e-06 | -13.61 | AAAYWAACM_V$HFH4_01 | MSigDB lists | AAAYWAACM_V$HFH4_01 | 239 | 63 | 17758 | 2588 |
REPS2,GRIK2,CAST,NDRG1,FAM134A,SYTL2,NEO1,FOXP2,HSF2,ITGA3,RALGPS2,GRHL1,CYR61,CALD1,BMP7,VASN,FLRT3,BDH1,KLF3,FOSB,MITF,SLC44A1,FAM63A,BCL6,SGK1,TACSTD2,TSPAN13,CRY2,IQGAP3,SCN2A,NCAM1,NTN1,MYLIP,HSPA2,DUSP1,MAP3K3,NFE2L3,SMARCA2,TRIM8,CXXC5,SPATA18,ASXL1,SLC39A8,SNTB2,RGAG1,H2AFV,IDH1,PRX,NFIX,KLF12,HOXA9,PAPD5,NKD1,NR4A3,PPP1CB,ADAMTS14,EFNA1,REEP4,SEMA3A,STARD13,MAFF,KLF7,RAD21 |
| 1.236e-06 | -13.60 | spindle | cellular component | GO:0005819 | 283 | 72 | 17570 | 2579 |
DLGAP5,RPS6KA1,XIAP,CCNB1,CALM2,RPS6KA2,CTNNB1,KIF14,CAPG,TUBG1,KIF22,CTTN,PLK1,PSRC1,AKT1,CAPN6,SEPT6,CCSAP,CDC20,VPS4B,CKAP2L,NUSAP1,AURKB,SLC25A5,CDK1,NIN,CEP162,PLEKHG6,FAM110C,RGS14,SGOL1,MAD2L1BP,HSPB1,ANXA11,MZT1,CKAP2,POC1B,CDCA8,KIF23,CALM3,RACGAP1,SPDL1,CKAP5,SAC3D1,RB1,MZT2A,FRY,TUBGCP6,NEK2,PRC1,KNTC1,ERCC2,NUP85,KIF20A,CEP89,ASPM,CALM1,PARP4,KBTBD8,KIF20B,KIF11,SKA1,FAM83D,AGBL5,AURKA,PKD2,PPP2R3C,CENPE,GEM,WDR62,NDE1,ESPL1 |
| 1.242e-06 | -13.60 | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | 156 | 46 | 17758 | 2588 |
NKX3-1,AGRN,NFKBIE,ZNF395,IL27RA,TRIB2,BAHD1,SLC20A1,PHLDA1,DNAJB9,IER3,BMP2,BTG3,TNS3,FAM46A,KCNN4,FLRT3,IL6ST,FJX1,TPST1,BCL6,DUSP10,KANK2,NFKB2,CITED2,TIPARP,DUSP1,PPIF,PLAUR,C3orf52,LITAF,PTGER4,COL7A1,ALCAM,EGFR,FZD7,PITX2,TAPBP,PLK2,HOXA9,FGD6,AURKA,ITGAV,SLC31A2,MAFF,TOB1 |
| 1.251e-06 | -13.59 | MODULE_223 | MSigDB lists | MODULE_223 | 142 | 43 | 17758 | 2588 |
GRN,IL15RA,IL15,HLA-F,DNAJC3,EPS8,SELL,ERBB2,IL18,FTH1,PDGFB,EMP2,TNFSF9,MXD1,HLA-A,PDGFA,IRAK1,TIMP1,CYR61,KCNN4,BCL6,TACSTD2,HLA-C,LAMP3,EMP3,RUNX3,BCAR1,CDK5R1,EDNRA,CD83,MDK,HLA-B,CD8A,BTG1,AREG,P4HA2,CSF1,NAB2,OSMR,UBE2C,CD81,CAPN1,CSRP2 |
| 1.267e-06 | -13.58 | Fc-epsilon receptor signaling pathway | biological process | GO:0038095 | 299 | 76 | 16441 | 2455 |
SPRED1,PSME2,CUL1,NRG2,ERBB2,RASGRP3,PSME1,ITPR2,PDGFB,SPTB,PDGFA,CALM2,PSMD1,SHC3,PSMC2,PLCG2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKCQ,ITPR3,IRS2,PLCG1,FYN,JAK1,PSMD3,NRG1,SPTBN5,GAB1,PSMC1,TNRC6C,TAB3,RASA2,PSMD7,PSMD10,CALM3,TEC,PHLPP1,FGF19,DUSP5,PTEN,PAK2,ERBB3,MAP3K7,NCAM1,SYK,PSMA5,CAMK2G,RASGRF1,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,FOS,PSMA4,RASA1,EGFR,BCL10,FGFR2,PHLPP2,FGF18,ITPR1,NFKBIA,UBE2D2,NR4A3,GRIN2D,JAK3 |
| 1.289e-06 | -13.56 | positive regulation of protein phosphorylation | biological process | GO:0001934 | 970 | 198 | 16441 | 2455 |
CCNC,TXN,ACVR1,TRIM5,CAMKK1,EPHA4,NRG2,PSME1,IL18,NENF,CCNB1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,PAK6,PSMD1,CTNNB1,CTGF,NPNT,SHC3,IL6ST,PSMC2,IL31RA,PIK3CA,DLG1,TNFRSF18,RASGRP1,PLK1,NEK4,SOD1,PRKAR2B,CDK1,PLCG1,GPRC5B,ANKRD6,TBX1,MADD,NOD2,MAP3K11,PRKCDBP,CAB39,F2RL1,PSMC1,GAB1,RASA2,SOX9,PRKAA1,PSMD7,CALM3,SORBS3,TEC,DUSP5,BMP2,IGF1R,CYR61,PAK2,MAP3K9,FNIP1,MDFIC,BRAT1,NPTN,MYDGF,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,MMD,MAPKAPK3,CALM1,PDE5A,STRADB,ILK,PSMA4,EGFR,RASA1,CDK5R1,FAS,MAPKAPK2,BCAR3,PRKAG2,INSR,SEMA4D,PELI2,PLPP3,CSF1,STK39,EFNA1,GDF11,MAP3K5,JAK3,XDH,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,EMP2,STIL,FLT3,PDGFA,CCND1,ST5,RALB,KIF14,DAB2IP,RASGEF1A,F2R,HSPA2,DVL2,FRS3,MAP3K3,SIRT1,TIMP2,PSRC1,BAG4,RIPK2,AKT1,FZD4,CD40,MAP3K6,FZD7,IRS2,FYN,JAK1,STK26,PSMD3,KIAA1804,SLC27A1,NRG1,SPTBN5,EFNA5,PRKAR1A,PINK1,TAOK2,NKX3-1,TAB3,TRAF2,SDC4,FLOT1,PSMD10,TGFBR1,GDF15,PKN1,FGF19,ICAM1,PDCD10,ADORA1,IRAK1,PTEN,KNDC1,BMP7,BAX,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,PDGFC,RASGRF1,HES1,ADAM17,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,YES1,BANK1,FGFR2,ACVRL1,FGF18,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,PKD2,GPER1,LRRK1,CENPE,FZD5,CD81 |
| 1.300e-06 | -13.55 | REACTOME_CELL_CYCLE_MITOTIC | MSigDB lists | REACTOME_CELL_CYCLE_MITOTIC | 306 | 76 | 17758 | 2588 |
CCNE2,SPC25,CEP70,TUBB4B,PSME2,PTTG1,NDC80,CUL1,NUF2,PSME1,KIF2C,CCNB1,PRKACA,CENPN,CCND1,CDKN2C,WEE1,PCNA,PSMD1,CCNA2,CNTRL,PSMC2,PLK4,CDKN1B,TUBG1,CDKN2D,TUBA4A,PLK1,CENPA,CDC20,PRKAR2B,AURKB,PKMYT1,CDC25C,CDK1,GINS4,PRIM1,PPP2R5A,RBL1,PSMD3,HDAC1,SGOL1,PPP2R5D,PSMC1,CENPI,PSMD7,CDCA8,ERCC6L,PSMD10,KIF23,CKAP5,RB1,CENPJ,TUBGCP6,NEK2,CKS1B,BUB1,KNTC1,NUP85,PSMA5,ZWINT,KIF20A,PSMB4,B9D2,MYBL2,POLD3,SKA1,PSMA4,E2F1,AURKA,SSNA1,CEP41,NUP37,CCNB2,UBE2C,RAD21 |
| 1.314e-06 | -13.54 | ESC_J1_UP_LATE.V1_UP | MSigDB lists | ESC_J1_UP_LATE.V1_UP | 185 | 52 | 17758 | 2588 |
LMO7,PRSS8,FARP1,SERPINE2,FXYD3,PDIA5,MORC4,SEPP1,PHLDA1,PARM1,CYP26A1,BMP2,ST5,SESN3,TGFBR3,CTGF,RNF128,CYR61,CTSC,GPC3,FUT8,ENPP5,DRAM1,TAX1BP3,TNFRSF12A,TINAGL1,LGMN,CITED2,NAGA,TPCN1,MYO5B,P2RX4,SGCE,ARAP2,CD55,PCDH1,CAPN6,SLC39A8,FHL2,PRICKLE1,LOXL2,TCN2,IRS2,SHROOM3,P4HA2,TDRD7,EFNA1,UNC5B,WBSCR27,CBX4,OCLN,FAM134B |
| 1.314e-06 | -13.54 | SERVITJA_LIVER_HNF1A_TARGETS_UP | MSigDB lists | SERVITJA_LIVER_HNF1A_TARGETS_UP | 133 | 41 | 17758 | 2588 |
GALK1,SORBS1,CDKN1C,NQO1,CDCA8,RACGAP1,KIF2C,MGST2,CCNB1,SLC20A1,TNFRSF19,WEE1,CCNA2,ADORA1,NPNT,NEK2,TNFRSF12A,BUB1,ALDH3A2,HMMR,MMD,KIF20A,SEPT6,CDC20,TMEM98,AURKB,TMTC2,ANLN,PCTP,KIF11,POR,LEPR,SLC25A4,GPRC5B,ABCB1,MAOA,PER3,UBE2C,CCNB2,SERPINB1,RRAGD |
| 1.326e-06 | -13.53 | response to growth factor | biological process | GO:0070848 | 765 | 162 | 16441 | 2455 |
CCNC,CASP3,ACVR1,NRG2,GATA3,F11R,PSME1,ITPR2,HDAC6,PDGFB,SPTB,CALM2,ZFYVE16,ZYX,PSMD1,RPS6KA2,TGFBR3,CTNNB1,CTGF,SHC3,ZCCHC12,PSMC2,PIK3CA,PPP1CA,PIK3CD,TIAM1,RASGRP1,CASP9,AGO4,PRKAR2B,ABR,PLCG1,TBX1,HDAC1,MAPK13,HSPB1,PSMC1,GAB1,PPP2R5D,FGD1,PCSK5,RUNX2,RASA2,SOX9,PSMD7,CALM3,PHLPP1,DUSP5,CORO1B,BMP2,MEGF8,FLRT3,PRKCI,C10orf54,NCAM1,MAPK7,PSMA5,EPB41L5,RGMB,MAPKAPK3,CALM1,ELK1,PSMA4,EGFR,RASA1,MAPKAPK2,IL1R1,FNTA,INSR,PHLPP2,ITPR1,NFKBIA,LTBP2,JAK3,RPS6KA3,EHD1,SPRED1,RPS6KA1,IQGAP1,PSME2,TP53,ERBB2,RASGRP3,EGR3,PRKACA,FLT3,ARHGEF16,ZFYVE9,PDGFA,ACAP2,RALB,CDKN1B,DAB2IP,TWIST1,RASGEF1A,FRS3,BAG4,AKT1,RIPK2,CBL,ITPR3,DUSP4,IRS2,FYN,JAK1,RBL1,NGFRAP1,PSMD3,WWTR1,PPP1CB,NRG1,SPTBN5,ARHGAP4,PRKAR1A,MAPK12,ANXA3,ARHGEF3,TNRC6C,SORT1,ARHGEF11,ARHGEF7,LRP4,PSMD10,TGFBR1,GDF15,FGF19,NRP2,IRAK1,ADRBK1,PTEN,BMP7,MCF2L,FUT8,MAPK11,ERBB3,MAP3K7,SPRY2,CAMK2G,TGIF1,RASGRF1,RHOA,ADAM17,PSMB4,RAPGEF2,NR4A1,PIK3R1,GRIN1,FURIN,RUNX3,YES1,FOS,BCAR1,FGFR2,ACVRL1,TWSG1,FGF18,E2F1,GRIN2D,ARHGEF9,ARHGEF4,RGMA,NGEF |
| 1.341e-06 | -13.52 | ERBB signaling pathway | biological process | GO:0038127 | 325 | 81 | 16441 | 2455 |
SPRED1,REPS2,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,SH3KBP1,PDGFA,CALM2,PSMD1,SHC3,PSMC2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,PRKAR2B,AGO4,ERBB2IP,CBL,ITPR3,ARF4,IRS2,PLCG1,FYN,JAK1,AREG,PSMD3,SPTBN5,NRG1,GAB1,PSMC1,PRKAR1A,TNRC6C,RASA2,ARHGEF7,EPS8,SOX9,PSMD7,PSMD10,CALM3,PHLPP1,FGF19,DUSP5,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,SOCS5,RASGRF1,ADAM17,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,BCAR1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,FGF18,ITPR1,GRIN2D,JAK3 |
| 1.347e-06 | -13.52 | CAMP_UP.V1_DN | MSigDB lists | CAMP_UP.V1_DN | 190 | 53 | 17758 | 2588 |
PINK1,ST13,ENO2,CAPN12,TUBB4B,ATP9A,ATP8A1,NDRG1,BACE1,SNN,OAT,KBTBD11,TTYH3,CHST2,PLS3,FRY,KCNN4,ZFP36,FUT8,FOSB,TRPC1,USP38,TLN2,TMBIM1,FAM134C,ATP2B1,TUBA4A,MYO5B,SYPL1,ATL1,TIMP2,DCAF6,TMEM98,EZR,GLO1,ESYT1,BCL2L13,DAG1,CD83,DPYSL3,DDAH1,CASP7,ETS2,MAP2,ANKRD6,CDCA7L,RAB31,MAL2,GEM,TANC2,ZMIZ1,PKIA,JARID2 |
| 1.347e-06 | -13.52 | GSE27786_NKCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_NKCELL_VS_NKTCELL_UP | 190 | 53 | 17758 | 2588 |
GSDMD,CASP3,SORT1,TXN,TGFBR1,NOTCH2,DHRS3,MAP1LC3B,SNX9,DUSP5,VPS26A,RASSF8,SNX13,SPP1,E2F7,TNS3,RPS6KA2,CA2,FAM20C,RALB,P4HB,LMAN2L,FAM63A,ATRNL1,IRF2,ABCD1,HMGCL,TFG,FAR1,STK35,MCCC2,FRS3,MAP3K3,MCTP1,VAMP3,ANLN,RNF19B,POR,NIN,PRDX4,RASGRP2,KLHL2,TNS4,TMEM50B,PPP2R5A,ABHD12,STK38,ADIPOR1,NFKBIZ,SLC31A2,SERPINB1,CSRP2,JARID2 |
| 1.347e-06 | -13.52 | GSE1460_DP_VS_CD4_THYMOCYTE_DN | MSigDB lists | GSE1460_DP_VS_CD4_THYMOCYTE_DN | 190 | 53 | 17758 | 2588 |
SCN5A,KLF2,EPAS1,HLA-E,CTSB,SOX9,PPFIBP2,PDIA5,SELL,ASAH1,BTN3A1,NDRG2,B4GALT4,DENND2D,BMP2K,PDIA4,SGPL1,SCML1,PDGFA,SP100,IL6ST,AIM1,PCYOX1,FAM102A,PIK3CD,HLA-C,PDE4D,ZNF365,SLC16A5,SCN3A,TUBA4A,CD55,ELK3,ERMP1,LAP3,EMP3,ULK2,ABR,RASGRP2,STK17A,EDNRA,FUCA1,KDSR,HLA-B,SCARB2,RPL12,UBE2D2,STAT1,NR4A3,ARRB1,TBC1D4,AHR,EHD1 |
| 1.347e-06 | -13.52 | GSE30083_SP1_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP4_THYMOCYTE_DN | 190 | 53 | 17758 | 2588 |
KLF2,SLC35D2,SLC25A24,TTC39B,TBC1D1,UBASH3B,ITGA6,GNE,MCTP2,TAP1,FAM78A,DSE,CDIPT,HERC6,SEPP1,FAM101B,FAM46C,IL18R1,DTX3L,ADD3,NUP210,KLF3,ANKRD12,SGK1,IL17RA,ABCD1,ALS2CL,GM2A,PQLC3,SNTB2,SYNE2,TTC7A,RAB3IP,SESN1,NDRG3,ATP10D,DHDH,ENDOD1,LDLRAP1,FAAH,MADD,NLRC5,APPL2,TDRD7,IRF7,HS3ST3B1,MAP3K5,ARSB,TRAF5,F2RL1,IFIH1,ABCA1,XDH |
| 1.365e-06 | -13.50 | cell migration | biological process | GO:0016477 | 771 | 163 | 16441 | 2455 |
TNK1,ACVR1,RET,EPHA4,HEXB,GATA3,F11R,PDGFB,DNER,SDC1,SH3KBP1,PAK6,TGFBR3,CTNNB1,CTGF,ELMO2,CDKL5,MITF,PIK3CA,PIK3CD,CTTN,SEMA3G,TIAM1,CYP1B1,MARK1,CELSR2,STRIP2,TNS1,LOXL2,ANLN,ZFAND5,CDK1,ARF4,LCP1,MDK,PLCG1,TBX1,F2RL1,SEMA6B,LGALS3,BVES,ITGA6,NCKAP1,S100A2,MERTK,CORO1B,TNS3,SPP1,ITGA3,CYR61,GATA2,MEGF8,FLRT3,PAK2,PRKCI,PRKG1,TNFRSF12A,BRAT1,ZRANB1,NTN1,NUP85,CCDC88A,EPB41L5,PODXL2,ANO6,SPATA13,STRADB,SCRIB,ILK,EGFR,CDK5R1,PTPRF,SEMA4D,PLPP3,ITGA7,MATN2,FAM83D,NR4A2,EFNA1,ATP1B3,NDE1,SHROOM2,SEMA3A,JAK3,DRD1,INPP5D,EGR3,DDR1,EMP2,APC2,ARHGEF16,NOV,ARTN,LHX6,SMO,DIXDC1,TWIST1,DAB2IP,EPHB4,PDE4D,TSPAN1,RASGEF1A,SCYL3,SEMA3B,DOCK4,SYNE2,PRKCQ,ATP1B1,FYN,JAK1,PTK7,CORO1C,AXL,PEX2,STAT1,NRG1,PLXND1,POMGNT2,CTHRC1,TAOK2,ADGRG1,CD63,ARHGEF7,SDC4,EPS8,SELL,TGFBR1,PKN1,EFNB1,FGF19,SIRPA,SIX4,ICAM1,GBX2,SGPL1,CXCL16,PDCD10,PTEN,FUT8,KIAA0319,BAX,SYK,PARP9,GCNT1,HES1,ADAM17,RHOA,NR4A1,RAPGEF2,ASPM,PIK3R1,YES1,BCAR1,GPLD1,PITX2,ARHGAP24,BTG1,SCG2,ACVRL1,ITGAV,SOX8,ARSB,L1CAM |
| 1.375e-06 | -13.50 | GSE7460_TCONV_VS_TREG_THYMUS_DN | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_DN | 195 | 54 | 17758 | 2588 |
CCDC109B,LGALS3,CHCHD7,S100A11,GMCL1,NOTCH2,NCKAP1,PLA2G16,PHLPP1,IL18R1,DUSP5,MXD1,NRP2,ITGB8,FAM46A,OSBPL3,KIAA0319,MDFIC,NTN4,TSPAN13,KLF9,AK3,PIM1,NTN1,SNX10,IL10RB,MGAT5,S100A6,IGSF3,CHSY3,TGIF1,ELK3,PLSCR1,PTPN9,CORO2A,S100A4,PTGER4,DUSP4,PRKRA,CD40,RNPEP,PCTP,CASP4,CD83,GABARAPL1,HLA-B,PRKAG2,KCNK1,PTER,DGAT2,SH3BGRL2,AHR,CSRP2,ACOT7 |
| 1.387e-06 | -13.49 | cellular response to growth factor stimulus | biological process | GO:0071363 | 743 | 158 | 16441 | 2455 |
CCNC,CASP3,ACVR1,NRG2,GATA3,F11R,PSME1,ITPR2,PDGFB,SPTB,CALM2,ZFYVE16,ZYX,PSMD1,RPS6KA2,TGFBR3,CTNNB1,CTGF,SHC3,ZCCHC12,PSMC2,PIK3CA,PPP1CA,PIK3CD,TIAM1,RASGRP1,CASP9,AGO4,PRKAR2B,ABR,PLCG1,TBX1,HDAC1,MAPK13,HSPB1,PSMC1,GAB1,PPP2R5D,FGD1,PCSK5,RUNX2,RASA2,SOX9,PSMD7,CALM3,PHLPP1,DUSP5,CORO1B,BMP2,MEGF8,FLRT3,PRKCI,C10orf54,NCAM1,MAPK7,PSMA5,EPB41L5,RGMB,MAPKAPK3,CALM1,ELK1,PSMA4,EGFR,RASA1,MAPKAPK2,INSR,FNTA,PHLPP2,ITPR1,NFKBIA,LTBP2,JAK3,RPS6KA3,EHD1,SPRED1,RPS6KA1,IQGAP1,PSME2,TP53,ERBB2,RASGRP3,EGR3,PRKACA,FLT3,ARHGEF16,ZFYVE9,PDGFA,ACAP2,RALB,CDKN1B,DAB2IP,TWIST1,RASGEF1A,FRS3,BAG4,AKT1,RIPK2,ITPR3,DUSP4,CBL,IRS2,FYN,JAK1,RBL1,NGFRAP1,PSMD3,WWTR1,PPP1CB,NRG1,SPTBN5,ARHGAP4,PRKAR1A,MAPK12,ARHGEF3,TNRC6C,SORT1,ARHGEF11,ARHGEF7,LRP4,PSMD10,TGFBR1,GDF15,FGF19,NRP2,IRAK1,ADRBK1,PTEN,BMP7,MCF2L,FUT8,MAPK11,ERBB3,MAP3K7,SPRY2,CAMK2G,TGIF1,RASGRF1,RHOA,ADAM17,PSMB4,RAPGEF2,NR4A1,PIK3R1,GRIN1,FURIN,YES1,FOS,BCAR1,FGFR2,ACVRL1,TWSG1,FGF18,E2F1,GRIN2D,ARHGEF9,ARHGEF4,RGMA,NGEF |
| 1.410e-06 | -13.47 | SH3 | smart domains | SM00326 | 217 | 62 | 9131 | 1455 |
BIN1,LASP1,TNK1,SORBS1,PACSIN2,TRIP10,MACC1,ARHGEF7,SH3D19,RUSC2,UBASH3B,EPS8,MPP5,SORBS3,TEC,CACNB4,SNX9,ARHGEF16,SH3KBP1,EPS8L2,SH3RF2,SH3D21,ARHGAP42,NOXA1,ARHGEF37,SNX18,MCF2L,FUT8,PLCG2,DLG1,MAP3K9,OSTF1,CTTN,PACSIN1,DLG3,NEB,DOCK4,CASK,MPP1,PIK3R1,SPATA13,YES1,DOCK5,BCAR1,MAPK8IP1,ARHGEF26,RASA1,TXK,PLCG1,ARHGEF19,FYN,TJP3,SH3BP4,SH3GLB2,KIAA1804,MPP2,MAP3K11,ARHGAP4,ARHGEF9,RUSC1,NGEF,ARHGEF4 |
| 1.437e-06 | -13.45 | endomembrane system organization | biological process | GO:0010256 | 441 | 103 | 16441 | 2455 |
SUN1,AGRN,NDRG1,ARFGEF1,PKP2,P2RX7,F11R,MPP5,CCNB1,SNX9,EMP2,SPTB,RAB15,NUP210,CDH1,ARL1,REEP1,DLG1,ZDHHC23,SUN3,LMAN1,ANO4,PACSIN1,F2R,FLOT2,SNX10,XKR8,PLK1,ATL1,CLCN3,SOD1,KCNIP3,BAG4,AKT1,COG2,TMEM43,SYNE2,VPS4B,EZR,SYP,KIF13A,ARFRP1,ATP1B1,RAB38,CDK1,OPTN,ZMPSTE24,SPTBN5,RAB29,REEP4,RTN3,CNEP1R1,ABCA1,PLSCR4,PACSIN2,SERPINE2,TSPAN15,ARHGEF7,FLOT1,ANO9,TSPAN17,LMNA,DOPEY2,ANK1,PDCD10,PTEN,FAM160A2,A4GALT,EXOC8,ATP8B1,PLEKHF1,ALS2CL,NUP85,TSPAN33,MYO5A,TMED2,SUN2,GCC2,RAB3B,PLSCR1,CRB3,RAPGEF2,ANO6,VAMP3,ATP8B3,FAM109A,BBS2,LEMD2,FAT4,FA2H,SYT7,PVRL2,HTT,RAB31,DYSF,GPER1,ATP1B3,NUP37,CCNB2,HOOK1,NUP58,DMPK,GOLGB1 |
| 1.441e-06 | -13.45 | RIGGINS_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_DN | 215 | 58 | 17758 | 2588 |
ANXA3,UPF3B,SOX9,ATP2C2,MTL5,ARFGEF1,LTBP3,CARD10,LGALS3BP,IL17RB,SCNN1A,RPS6KA2,IGF1R,TIMP1,EFR3A,FRYL,IL6ST,AIM1,DLG1,CDH3,STEAP3,NFU1,ACOX2,MAP3K7,BTBD3,CYP1B1,WBP5,LAMP2,CPD,NFE2L3,CASK,IFITM3,TACC1,LAP3,LGALS8,RAPGEF2,PIK3R1,SYBU,PYGL,RAB38,ALCAM,PLEKHB1,MAPKAPK2,MFAP3L,AP1AR,SCARB2,RBM47,PDLIM3,DHRS2,NAT1,NMI,STAT1,RAB31,INPP4B,ACADM,IFIH1,IFI6,FAM134B |
| 1.460e-06 | -13.44 | endoplasmic reticulum membrane | cellular component | GO:0005789 | 929 | 188 | 17570 | 2579 |
UNC93B1,FAF2,IL15RA,PNPLA2,DNAJC3,TAP1,ITPR2,PJA2,CDIPT,PIGL,ABCD4,CYP1A1,NUP210,STIM1,LMAN2L,CYP2S1,RDH14,DLG1,MARCH2,TECR,SCARA3,TRAM1,RASGRP1,ERAP2,CYP1B1,CERS2,ATL1,NFE2L1,KDELR3,ERP44,ESYT1,MCFD2,ICMT,PTGFRN,POR,CYP4F3,RAB2B,RHEB,VCP,SGPP1,KDSR,AGPAT2,AREG,DOLPP1,SARAF,PIEZO1,TTC9,POMT1,RTN3,SEC61G,HLA-E,HLA-F,FXYD3,CYP2J2,ELOVL7,NOTCH2,DHRS3,PGAP1,CALR,NECAB3,FLRT3,SUCO,SELK,HLA-C,STT3B,FAR2,MOXD1,ALDH3A2,TMED2,CKAP4,KDELR1,FAM69A,EPHX1,PIGC,CYP26B1,FADS2,UFD1L,LPGAT1,ERO1A,EMC2,MEST,SPTLC2,EGFR,CYB5A,MOSPD3,FA2H,FAAH,PLPP3,MFSD2A,ITPR1,DGAT2,SAMD8,PLD1,ALG2,MAP3K5,APOL2,TMEM173,DRD1,DMPK,PLA2G4A,APOO,XYLT1,PDIA5,MGST2,LPIN3,EXT2,CYP39A1,KTN1,BCAP31,CYP26A1,CDS1,CYP4F11,XYLT2,REEP1,RPN2,ACSL4,NOTCH3,LMAN1,PDIA6,SOAT1,MX1,SEC23A,SEC61B,ERMP1,EVA1A,C3orf52,SYNE2,CLSTN1,PKMYT1,DNAJB14,TMTC2,ITPR3,TRIQK,CASP4,ATP10D,ZMPSTE24,PTGS2,TAPBP,DDOST,SLC9A6,WFS1,PNPLA6,CANT1,CYP2U1,REEP4,NR3C2,POMGNT2,FAM134B,SORT1,CDS2,HSP90B1,JKAMP,TRAF2,SCD5,PLD2,LBR,HLA-A,DNAJB9,SGPL1,ALG13,RRBP1,BAX,UBE2J1,TMBIM6,SGK1,TMX1,CAMK2G,MLEC,RHOA,PLAUR,AMFR,ELOVL3,EIF5A2,FURIN,CARD19,TXNDC11,MAPK8IP1,HLA-B,PLOD2,PGRMC1,ERAP1,PKD2,GPER1,SPCS3,PLOD3,PTGES,ABCG1,ESYT2 |
| 1.471e-06 | -13.43 | signaling | biological process | GO:0023052 | 5199 | 877 | 16441 | 2455 |
DOC2A,ADD1,IL15RA,GRIK2,TRIM5,DNAJC3,RET,XIAP,NRG2,IL18,BAIAP3,SYTL4,CA8,SPSB1,CARD10,GRM5,TP73,CALM2,DAPK2,ZYX,ARHGAP42,PSMD1,RGS12,TGFBR3,DNM2,CLDN4,CRY2,SEMA3G,PPP1CA,PIK3CD,TIAM1,IL10RB,TIPARP,CPE,NEK4,TNIP1,CDA,KDELR3,TFAP2C,PRKAR2B,ARF4,LCP1,ABR,PGF,CARHSP1,PLCG1,DNM1L,LIMK1,MYLK,NOD2,MAP3K11,HDAC1,TMOD2,RNASEL,ITPKA,ARF6,HSPB1,STARD13,GAB1,SCN5A,NUAK1,SEC61G,ITGA6,SOX9,RAB23,GPSM2,ZNRF3,MERTK,HPCAL4,LMNA,TFAP4,RAC2,MEGF8,FLRT3,FAM13B,RANBP1,MAP3K9,MYDGF,PANX2,CNGA1,NCAM1,MAPK7,DGKG,NUP85,PAQR7,MAPKAPK3,SALL4,STAT4,ERO1A,SHARPIN,FHL2,CALCRL,ELK1,NPHP3,ILK,GNA11,PSMA4,RHOB,STK17A,PTPRF,IL1R1,NCOA3,FNTA,HTT,SEMA4D,ITPR1,OSMR,STK39,GDF11,NDE1,ARPC2,TRPC3,NUP58,RPS6KA3,DOCK9,DMPK,ARHGAP11A,NQO1,LFNG,INPP5D,CD82,PKP2,NUF2,IL13RA1,MAPK4,GRK6,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,TAX1BP3,RTKN2,ARL4D,DLG3,RASGEF1A,RAB27B,SCN3A,MX1,SEC61B,RIPK2,FZD4,RAB38,GIGYF1,IRS2,CORO1C,WFS1,SLC9A6,AXL,SIPA1L1,WWTR1,INPP4B,TRABD2A,RGS14,ARNT,MAPK12,CTHRC1,TAOK2,NKX3-1,TNRC6C,HSP90B1,MPZL1,TRAF2,CCM2,SDC4,RASSF7,FLOT1,BTN3A1,PDIA3,PKN1,PLPPR4,ZNF219,KCNC4,IFT27,NFAT5,ICAM1,SGPL1,CTNNBIP1,DIRAS3,ANK1,PDCD10,ITGB8,IRAK1,KNDC1,GPC3,MCF2L,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,HCN3,AMOTL2,CTNNAL1,BCL9,RAPGEF2,PIK3R1,GRIN1,NEURL1B,SKA1,TXK,CNTNAP1,KIAA0141,RAB11FIP2,NR1D2,ACVRL1,SYT7,NR4A3,SSNA1,ITGAV,CENPE,NUP37,CD81,FOXA1,MYL9,SIGIRR,UNC93B1,TNK1,BCAM,AGRN,EPAS1,EPHA4,NDC80,NDRG2,DNAJB11,F11R,TEX2,ITPR2,PDGFB,SDC1,SPTB,NUP210,RPS6KA2,CTNNB1,SHC3,IL6ST,ARL1,PSMC2,MITF,DUSP10,TNFRSF18,NTN4,SCARA3,PLK1,THRB,KCNIP3,MCTP1,MARK1,CELSR2,CR2,EZR,ARFRP1,VCP,RHEB,PLEKHB1,OPTN,TRIM9,PLCH1,KCNMB4,WIPI1,CTNND1,KPNA2,PIK3C2B,TC2N,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,RASA2,HLA-F,PDCL,PSMD7,RACGAP1,RAB6A,NCKAP1,CNTNAP2,DOCK11,FBLN1,DHRS3,IL18R1,ANO1,BMP2,RB1,VASP,IGF1R,KIF13B,PAK2,SELK,MDFIC,PIM1,NTN1,WNT3A,PLCB2,PSMA5,DPYSL5,PCDH1,RGMB,CORO2A,STRADB,SCRIB,TCF7,PDK3,IFIT3,NMT2,CDK5R1,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,LTBP2,PLD1,SEMA3A,IFI6,RNF146,KCNAB3,NF2,FOXM1,DGKA,TP53,CCDC68,P2RX7,RHPN2,ERBB2,RASGRP3,STIL,BCAP31,SYTL2,IER3,CDK14,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,NOTCH3,OAS3,SCN2A,CTDSP2,DVL2,SULF2,CTH,SIRT1,CLCN3,MBP,AKT1,CDC20,PTGER4,MYL12A,DUOX1,DNAJC10,PTPRJ,ATP1A1,IDE,RBL1,PSMD3,PTK7,STK38,MAOA,EFNA5,IRF7,ANXA9,SYT13,ARHGAP4,ZMAT1,PINK1,CPEB4,ADGRG1,TAB3,DAP,CTSB,GNAL,MCTP2,CDCA8,ERCC6L,GABRG2,PSMD10,GDF15,JAG2,CRABP2,AIP,IL22RA1,DNAJB9,FZD6,PPP2R3A,NRP2,M6PR,CDK16,SGK1,IL17RA,TRIM21,BUB1,TSPAN13,CPLX1,SYK,CAMK2G,DUSP1,P2RX4,DLGAP1,HES1,RHOA,PSMB4,NR3C1,IFITM3,AMFR,PLAUR,LITAF,PPARA,MAML2,AKAP3,PELI3,BCAR1,BBS2,MAPK8IP1,DGKE,BCL10,CD83,PRDX4,DDAH1,FAT4,TWSG1,SCG2,NMI,FGF18,E2F1,PKD2,ICOSLG,NDFIP1,PTGES,ARHGEF9,ZBTB33,ARHGEF4,LAMP1,TXN,ACVR1,LGR4,HSPG2,KLC2,CUL1,GATA3,PDGFRL,PSME1,PLXNA1,PJA2,SLC20A1,CENPN,PICK1,NCS1,PAK6,CTGF,ELMO2,IL31RA,KCNS3,PIK3CA,IRF2,ATRNL1,TACSTD2,TFG,RCAN3,METAP2,ACVR1C,CASP9,BNIP3L,AGO4,AURKB,SAV1,ZFAND5,RAB2B,ULK2,SGPP1,AREG,PLK2,TBX1,SH2D3C,NKD1,EIF4EBP2,MAPK13,UNC5B,F2RL1,TRAF5,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,PRKAA1,AKAP17A,SLC1A3,NOTCH2,APBA1,TNFRSF19,TSPAN7,MESDC2,CALR,ITGA3,RALGPS2,CYR61,PIK3AP1,PPP4R1,MSH2,DAPK1,PRKG1,OPN3,SORL1,CD70,TNFRSF12A,OSTF1,CACNA1D,PIKFYVE,MAST4,SYTL3,GPR161,EEF1D,RIMS2,SOCS5,GFPT1,PRODH,KCNJ12,B9D2,MICB,CALM1,AMER1,ANO6,DCHS1,EPHA1,CYFIP2,KDM3A,ANTXR1,RASA1,STX3,PDE11A,FAS,DGKH,GABRD,PRKAG2,PELI2,CSNK1G1,ARAP1,APPL2,MPP2,PIAS2,NR4A2,CABIN1,EFNA1,MAP3K5,IFIH1,IRF1,SPRED1,DLGAP5,TCTN2,REPS2,S100A11,TRIP10,THRA,RPS6KA1,IQGAP1,NDRG1,RALBP1,CD274,EGR3,BCL2L1,FLT3,DDR1,GNB2,ZFYVE9,EPS8L2,APLP2,NOV,CCNA2,RALB,DOK4,CDKN1B,DAB2IP,PDE4D,IFIT1,EPHB4,LGMN,TSPAN1,NR2C1,MED30,SEMA3B,DOCK4,DMTN,PRKCQ,ATP1B1,PYGO1,ASB13,CBL,ITPR3,ALCAM,FZD7,EPHA10,FYN,JAK1,PPP2R5A,STK26,NGFRAP1,TSPAN18,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,RAB29,NR3C2,PRKAR1A,ARHGEF3,DEPDC1,IGFBP6,CENPI,EPS8,ARL4C,HERC5,GPR180,PLD2,SPDL1,EFNB1,FGF19,LGALS3BP,TEAD3,ADGRB2,HLA-A,RND1,CKAP5,RASSF8,E2F7,GNB5,PTEN,FUT8,FJX1,PRC1,SGK3,CD9,SLC44A2,ERBB3,CITED2,MAP3K7,CNPY3,TRIM62,SPRY2,MSH6,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,ARAP2,ZWINT,CASK,ALDH2,ARHGEF28,MPP1,FURIN,DIAPH2,YES1,FOS,GPLD1,RGS9,FGFR2,RIN3,RYK,GRIN2D,RABL6,GPER1,LRRK1,FZD5,MELK,RGMA,CCNC,LTBP1,CASP3,CAMKK1,UBE2Q1,KIF2C,CACNB4,DNER,KREMEN1,TRIM68,PTCHD4,SH3KBP1,HTR1D,ZFYVE16,EPCAM,RAB15,ZCCHC12,SIVA1,TSPAN6,DPYSL2,DLG1,AKR1B1,RAB20,MYH14,CTTN,PTPRE,IL1RAP,RASGRP1,CYP1B1,SOD1,CXXC5,TRIM8,CENPA,ITCH,USP18,ARHGDIB,ROR1,STK17B,ADRBK2,EDNRA,MDK,CXXC4,GPRC5B,KCNK1,MADD,CAB39,ADIPOR1,APBA2,NRGN,RAP1GAP,PSMC1,PPP2R5D,NR2C2,PCSK5,GRN,ARAP3,PPP1R12A,LRRFIP2,ETV5,ASB9,ATP6V1E2,CALM3,TEC,PHLPP1,DUSP5,CA2,NOXA1,LRRN2,OCRL,KCNN4,PRKCI,DIAPH2-AS1,FNIP1,NPTN,C10orf54,HLA-C,KNTC1,ZRANB1,GAD1,CCDC88A,MDFI,ELK3,PDE5A,EGFR,RHPN1,GNAS,BCAR3,TSC1,ONECUT1,INSR,PLPP3,NFKBIA,RAB31,RHOBTB2,NXPH4,YOD1,JAK3,TOB1,COL16A1,RARG,DRD1,SORBS1,SPC25,IL15,SLC2A8,PSME2,PDIA5,SOD2,IL27RA,MRAS,EXT2,ARHGEF16,SS18,ARTN,KIF14,SMO,GOT1,DIXDC1,NFKB2,F2R,PDIA6,FRS3,CHP1,MAP3K3,BAG4,KREMEN2,PTPRU,ERBB2IP,DUSP4,CD40,DOCK5,CDC25C,MAP3K6,CASP4,ARHGAP35,SOCS3,ALDH5A1,STAT6,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,PLXND1,SGOL1,LIFR,ABCA1,SORT1,ARHGEF11,CIT,ARHGEF7,LRP4,TGFBR1,AES,NOTUM,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,IL17RB,ADORA1,ADRBK1,BMP7,ZDHHC13,BRD7,IQGAP3,MYO5A,SYPL1,ADAM17,RAB3B,WNT10B,CENPC,NR4A1,DEPDC4,NDRG3,LEPR,FOXL1,CTSL,ARHGAP24,HLA-B,CD8A,CASP7,RND3,RAP2C,DTX4,UBE2D2,ARRB1,UACA,GEM,ATP6V1C1,SOX8,AHR,L1CAM,CD33,SNPH,NGEF |
| 1.499e-06 | -13.41 | axon development | biological process | GO:0061564 | 699 | 150 | 16441 | 2455 |
MYL9,AGRN,EPHA4,GATA3,NRG2,PSME1,PLXNA1,CACNB4,PDGFB,SPTB,CALM2,PSMD1,RPS6KA2,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,MYH14,TIAM1,RASGRP1,ATL1,RNF165,EZR,ULK2,DPYSL3,PLCG1,MAP2,LIMK1,UNC5B,PSMC1,MYL12B,SCN5A,RASA2,PSMD7,CALM3,DUSP5,RAC2,VASP,IGF1R,LRRN2,MEGF8,FLRT3,PAK2,COL6A1,CACNA1D,NCAM1,WNT3A,NTN1,PSMA5,DPYSL5,RGMB,CALM1,EPHA1,DPYSL4,NFIB,PSMA4,RANBP9,RHOB,EGFR,CDK5R1,RASA1,SEMA4D,MATN2,PITPNA,NR4A2,EFNA1,B4GAT1,ARPC2,JAK3,SEMA3A,TRPC3,RPS6KA3,KLF7,SPRED1,PSME2,RPS6KA1,ERBB2,RASGRP3,PDGFA,ARTN,DAB2IP,EPHB4,RASGEF1A,DLG3,ETV4,SEMA3B,FRS3,COL6A2,PRKCQ,ALCAM,DAG1,MYL12A,ARHGAP35,EPHA10,IRS2,FYN,RTN4RL1,JAK1,SLC9A6,PSMD3,SPTBN5,NRG1,EFNA5,PLXND1,COBL,COL9A3,ARHGEF11,ARHGEF7,FLOT1,PSMD10,COL4A5,PLPPR4,EFNB1,FGF19,NRP2,ITGA2B,RND1,NEO1,GBX2,KIF5B,ANK1,PTEN,BMP7,ERBB3,CAMK2G,S100A6,FARP2,RASGRF1,RHOA,ARHGEF28,B3GNT2,PSMB4,RAPGEF2,GRIN1,YES1,ABLIM2,MAP1B,CNTNAP1,FGFR2,FGF18,PGRMC1,RYK,NR4A3,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 1.513e-06 | -13.40 | enzyme activator activity | molecular function | GO:0008047 | 454 | 105 | 16491 | 2452 |
ARHGAP11A,CASP3,PSME2,IQGAP1,RALBP1,ARFGEF1,RGS20,RASGRP3,PSME1,MGST2,PDGFB,ELMOD2,CALM2,SIPA1L2,ACAP2,ARHGAP42,RGS12,RABEP2,SH3BP1,ARL1,RGS3,PIK3CA,CDKN1B,RGS5,DAB2IP,RP2,GM2A,EBAG9,TBC1D10B,DOCK4,TIMP2,CASP9,ARHGDIB,ATP1B1,PRKRA,VCP,ABR,ARHGAP35,SEC14L2,DNAJC10,PLEKHG6,TBC1D17,ARHGEF19,GPRC5B,NGFRAP1,MMP17,MADD,SIPA1L1,PPP2R4,CAB39,AGFG2,EFNA5,NRG1,ARHGAP4,RGS14,RAP1GAP,STARD13,PINK1,ARAP3,PCOLCE,NKX3-1,DEPDC1,ARHGEF11,TBC1D1,RASA2,CALM3,RACGAP1,FBLN1,SYDE2,BMP2,CARD8,NOXA1,LLGL2,RINL,CTSC,OCRL,TBCD,PAK2,RANBP1,FAM13B,ERBB3,IQGAP3,ALS2CL,SPRY2,ARAP2,TBC1D8B,RAPGEF2,CALM1,RGCC,BCL2L13,GRTP1,CDK5R1,RASA1,BCL10,ARHGAP24,MMP15,RGS9,PRKAG2,RIN3,ARAP1,ARRB1,ARFGAP3,CTSA,ATP1B3,TBC1D4 |
| 1.513e-06 | -13.40 | nuclear outer membrane-endoplasmic reticulum membrane network | cellular component | GO:0042175 | 947 | 191 | 17570 | 2579 |
UNC93B1,FAF2,IL15RA,PNPLA2,DNAJC3,TAP1,ITPR2,PJA2,CDIPT,PIGL,ABCD4,CYP1A1,NUP210,STIM1,LMAN2L,CYP2S1,RDH14,DLG1,MARCH2,TECR,SCARA3,TRAM1,RASGRP1,ERAP2,CYP1B1,CERS2,ATL1,SYNE3,NFE2L1,KDELR3,ERP44,ESYT1,MCFD2,ICMT,PTGFRN,POR,CYP4F3,RAB2B,RHEB,VCP,SGPP1,KDSR,AGPAT2,AREG,DOLPP1,SARAF,PIEZO1,TTC9,POMT1,RTN3,SEC61G,HLA-E,FXYD3,HLA-F,CYP2J2,ELOVL7,NOTCH2,DHRS3,PGAP1,CALR,NECAB3,FLRT3,SUCO,SELK,HLA-C,STT3B,FAR2,MOXD1,ALDH3A2,TMED2,CKAP4,KDELR1,FAM69A,EPHX1,PIGC,CYP26B1,FADS2,UFD1L,LPGAT1,ERO1A,EMC2,MEST,SPTLC2,EGFR,CYB5A,MOSPD3,FA2H,FAAH,PLPP3,MFSD2A,ITPR1,DGAT2,SAMD8,PLD1,ALG2,MAP3K5,APOL2,TMEM173,DRD1,DMPK,PLA2G4A,APOO,XYLT1,PDIA5,MGST2,LPIN3,EXT2,CYP39A1,KTN1,BCAP31,CYP26A1,CDS1,CYP4F11,XYLT2,REEP1,RPN2,ACSL4,NOTCH3,LMAN1,PDIA6,SOAT1,MX1,SEC23A,SEC61B,ERMP1,EVA1A,C3orf52,SYNE2,CLSTN1,PKMYT1,DNAJB14,TMTC2,ITPR3,TRIQK,CASP4,ATP10D,ZMPSTE24,PTGS2,TAPBP,DDOST,SLC9A6,WFS1,PNPLA6,CANT1,CYP2U1,REEP4,NR3C2,POMGNT2,CNEP1R1,FAM134B,SORT1,CDS2,HSP90B1,JKAMP,TRAF2,SCD5,PLD2,LBR,HLA-A,DNAJB9,SGPL1,ALG13,RRBP1,BAX,UBE2J1,TMBIM6,SGK1,TMX1,CAMK2G,MLEC,RHOA,PLAUR,AMFR,ELOVL3,EIF5A2,FURIN,CARD19,TXNDC11,CPTP,MAPK8IP1,HLA-B,PLOD2,PGRMC1,ERAP1,PKD2,GPER1,SPCS3,PLOD3,PTGES,ABCG1,ESYT2 |
| 1.516e-06 | -13.40 | VANTVEER_BREAST_CANCER_METASTASIS_DN | MSigDB lists | VANTVEER_BREAST_CANCER_METASTASIS_DN | 111 | 36 | 17758 | 2588 |
CCNE2,SPC25,DEPDC1,DLGAP5,HJURP,NDRG1,NDC80,MCCC1,PSMD7,GPR180,GPSM2,CENPN,QSOX2,KIAA1147,OXCT1,CDK16,KIF14,MGAT4A,PRC1,BUB1,SMC4,CKS2,CENPA,ASPM,GGH,NUSAP1,B3GALNT2,FAM64A,DCK,ZDHHC20,AURKA,CCNB2,MELK,NIPA1,RRAGD,RAD21 |
| 1.522e-06 | -13.40 | macromolecular complex binding | molecular function | GO:0044877 | 1394 | 269 | 16491 | 2452 |
ACVR1,TRIM24,ADD1,GATA3,SNX9,KIF26A,PICK1,TP73,NPM2,TGFBR3,CTGF,UBE2T,STIM1,DNM2,PPP1CA,SMARCA2,KIFC2,UXT,MTRF1L,KIF13A,LOXL2,LCP1,ENPP1,PLK2,TRAF3IP1,HDAC1,RNASEL,ANXA11,HOXC13,MRC2,ITGA6,SOX9,PRKAA1,STRN4,KIF23,NDUFA4,APBA1,PSIP1,CALR,ITGA3,CYR61,MSH2,SORL1,UFD1L,KIF20A,PYM1,SHARPIN,WHSC1,PLS1,KIF20B,PKM,ELK1,ILK,ANTXR1,GNA11,PTPRF,AP1AR,NCOA3,FNTA,FAM83D,CABIN1,NDE1,ARPC2,CBX5,IFIH1,ELK4,KIF3C,MTM1,GRHL2,THRA,IQGAP1,NDRG1,SUZ12,PKP2,PRKACA,APC2,DDR1,GNB2,CCND1,NOV,SP100,DOK4,CDKN1B,DAB2IP,RNF169,CAMSAP3,SEC61B,PSRC1,COG2,CAPN6,SYNE2,UTRN,KIF1C,NUSAP1,ATP1B1,RAB38,EBF2,GABARAPL1,IRS2,FYN,SHROOM3,CORO1C,TRIOBP,MLKL,RGS14,CBX7,PCOLCE,TRAF2,NES,PKN1,SPDL1,HDGFRP2,ICAM1,HLA-A,PTEN,TUBGCP6,PRC1,BAX,KLC3,CD9,ADAM15,CITED2,MSH6,CRTAP,NCOA2,TGIF1,LCA5,FMN1,CTNNAL1,PIK3R1,EIF5A2,AIF1L,FOS,SKA1,KIF11,CRTC2,CDK5RAP1,PITX2,RGS9,LDLRAP1,ACVRL1,GPER1,HMGA1,CENPE,CD81,CPEB2,JARID2,PHC1,CASP3,ST13,KIF2C,HDAC6,MAP1LC3B,PDGFB,SPTB,EPCAM,PCNA,CTNNB1,GRHL1,P4HB,NPNT,DPYSL2,MITF,CAPG,ASH2L,KIF22,MYH14,TLN2,THRB,PLK1,CENPA,SYNE3,ITCH,C12orf65,EZR,VCP,MSL1,MAP2,PRKAA2,LASP1,USH1C,RUNX2,LGALS3,PEX6,DNAJB2,PDCL,RACGAP1,NCKAP1,FBLN1,CORO1B,IGF1R,GATA2,ICAM5,KIF13B,FCHO1,SRP54,PIM1,CCDC88A,HP1BP3,DPYSL5,CORO2A,HMG20B,TCF7,EGFR,GNAS,H1F0,PLPP3,CDCA5,NFKBIA,KIF12,SHROOM2,APOL2,COL16A1,DRD1,GAS2L1,LZTFL1,SORBS1,NF2,TP53,MICALL2,BAHD1,EMP2,BCAP31,PDGFA,KIF14,REEP1,BCL6,ESPN,RPN2,NFKB2,CHP1,FRS3,SIRT1,TIMP2,ERBB2IP,KCTD2,DAG1,TLE1,SPTBN5,REEP4,CBX4,CPEB4,ADGRG1,CTSB,GNAL,HMGN3,ITGA2B,HMGXB4,TOP2A,KIF5B,ADORA1,TOX2,TFAP2A,H2AFY,CLIP2,SYK,SUN2,FBLN5,ADAM17,HMGN5,AMFR,SYBU,PPARA,MAP1B,CTSL,CTSV,TADA2B,ARRB1,L1CAM |
| 1.524e-06 | -13.39 | carbohydrate derivative binding | molecular function | GO:0097367 | 2195 | 401 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,FBXO2,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,TGFBR3,CTGF,UBE2T,DNAH6,ATP13A3,PIK3CA,DNM2,TUBG1,PIK3CD,TUBA4A,NEK4,NWD1,SMARCA2,KIFC2,ACVR1C,PBK,HSPA12A,CDA,PRKAR2B,KIF13A,PIF1,AURKB,POR,RAB2B,ARF4,ULK2,PGF,ENPP1,DNM1L,PLK2,LIMK1,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,KIF23,MERTK,BMP2K,C9orf69,CALR,RAC2,ITGA3,CYR61,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,CNGA1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,ATP8B3,PKM,ILK,GNA11,RHOB,RASA1,PDE11A,STK17A,DHX32,DGKH,PTPRF,PRKAG2,CSNK1G1,DCK,AURKA,STK39,CDK18,FBXO27,MAP3K5,IFIH1,NRBP1,RPS6KA3,TMEM173,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,PRKACA,FLT3,DDR1,MOCS1,NOV,APLP2,CDH1,TRANK1,RALB,FICD,PDE4D,ACSL4,EPHB4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,CDK19,STK26,AXL,KIAA1804,RAB29,PDXK,MLKL,MAPK12,PRKAR1A,GALK1,PCOLCE,TAOK2,HSP90B1,HAPLN3,ATP9A,ARL4C,FBXO6,PKN1,DNAH3,IFT27,RND1,DIRAS3,IRAK1,GPC3,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,RAPGEF2,UBE2A,AK4,PIM3,YES1,KIF11,CPTP,CRISPLD2,TXK,FGFR2,ACVRL1,ABCB1,RYK,RABL6,CENPE,LRRK1,CMPK2,MELK,RGMA,TNK1,NMRK1,ST13,AGRN,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,SDC1,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PSMC2,PAPSS1,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,RASGRP1,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,CDK1,ADRBK2,STK17B,VCP,RHEB,DPYSL3,MDK,PI4K2B,MAP2,IARS2,PIK3C2B,GLA,PSMC1,RRAGD,PRKAA2,RUNX2,LMTK3,SERPINE2,BVES,PEX6,ABCG2,TEC,RAB6A,MYO5C,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,PIM1,ABCC1,PODXL2,TESK1,GYLTL1B,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,COL13A1,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,LTBP2,KIF12,JAK3,RNF146,UGP2,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,SYTL2,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,SEPHS1,MAP3K3,CLCN3,ERLEC1,AKT1,RFK,FIGNL1,MAP3K6,DAG1,ARHGAP35,ATP13A2,IDE,ATP1A1,STK38,PTK7,XRCC3,ANXA9,RPL22,ABCA1,PINK1,DYRK3,TOR4A,SHPRH,CIT,CTSB,GNAL,GNE,ERCC6L,SELL,TGFBR1,NRP2,KIF5B,TOP2A,ADORA1,ADRBK1,CDK16,BMP7,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,ATP2B1,MYO5A,HMMR,P2RX4,RHOA,RAB3B,PSMB4,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,CTSL,SWAP70,SERPINA1,RND3,FIBCD1,RAP2C,UBE2D2,GLB1,GEM,UBE2C,L1CAM,HIPK3,ABCG1 |
| 1.528e-06 | -13.39 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | 181 | 51 | 17758 | 2588 |
CCNE2,EPAS1,SDC4,MIER3,GATA3,FAM102B,RASGRP3,F11R,KCTD9,ZFYVE9,NRP2,DNAJB9,UHRF1BP1L,EPDR1,WDR44,KCNK5,ENPP5,TSPAN13,NFU1,RAB27B,PTPRE,GFI1,SMC4,FAM69A,CTH,GFPT1,CLCN3,PHF20L1,UFD1L,CD55,HPS3,ERMP1,ERLEC1,ZNF84,CTNNAL1,SLC39A8,STAT4,SNTB1,C3orf58,FOXL1,SPAG1,SP4,MOSPD3,LEMD2,NCOA3,FYN,CTNS,SPINT2,MAOA,RNF146,NIPA1 |
| 1.590e-06 | -13.35 | Signaling by Rho GTPases | REACTOME pathways | R-HSA-194315 | 399 | 95 | 8202 | 1235 |
MYL9,ARHGAP11A,SPC25,NF2,TRIP10,RALBP1,IQGAP1,KLC2,NDC80,RHPN2,NUF2,KIF2C,CENPN,KTN1,ARHGEF16,CALM2,CTNNB1,CDH1,KIF14,CDKN1B,TAX1BP3,CTTN,MYH14,TIAM1,DVL2,PLK1,CENPA,CDC20,ARHGDIB,AURKB,CDC25C,ABR,ARHGAP35,PPP2R5A,LIMK1,MYLK,PPP1CB,ARHGAP4,SGOL1,STARD13,MYL12B,PPP2R5D,FGD1,WASF3,ARAP3,ARHGEF3,PPP1R12A,ARHGEF11,CIT,ARHGEF7,CENPI,CDCA8,ERCC6L,CALM3,RACGAP1,NCKAP1,PKN1,SPDL1,SYDE2,CKAP5,KIF5B,RAC2,NOXA1,OCRL,MCF2L,PAK2,FAM13B,KLC3,PRC1,BUB1,KNTC1,IQGAP3,NUP85,NCOA2,ARAP2,RHOA,ZWINT,CENPC,B9D2,CALM1,DIAPH2,CYFIP2,SKA1,RHOB,RHPN1,ARHGAP24,ARAP1,RHOBTB2,CENPE,NUP37,ARPC2,NDE1,ARHGEF9,NGEF,ARHGEF4 |
| 1.603e-06 | -13.34 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_UP | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_UP | 191 | 53 | 17758 | 2588 |
DDX58,ARHGAP11A,NCKAP5,ILDR1,EPAS1,AK7,SDC4,EPHX4,KCTD12,RACGAP1,TRMT2B,EGR3,PIGL,FAM46C,HMGXB4,SYTL2,KIAA1147,IL17RB,SAP130,APOBEC3B,FAM111A,SLC25A45,UBE2Q2,LMAN2L,OSBPL3,NEK2,PLEKHF1,MAP3K7,NAGA,TMBIM1,GCNT1,HMMR,P2RX4,ERMP1,FZD4,CORO2A,CKAP2L,ZSCAN12,RAD17,IFIT3,CMTM7,OPTN,RCBTB2,ANKRD6,NR4A3,DCUN1D1,SPCS3,TMEM159,NDFIP1,GLCCI1,CBX7,AHR,XDH |
| 1.603e-06 | -13.34 | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 191 | 53 | 17758 | 2588 |
ANXA3,PACSIN2,S100A11,CD63,RPS6KA1,SAMD9,MICALL2,MAP1LC3B,GNB2,BMP2K,HLA-A,SIRPA,ICAM1,KIF5B,APLP2,ZYX,PTEN,BCL6,IRF2,IFIT1,HLA-C,PTPRE,CDKN2D,IL1RAP,MYO5A,CERS2,DNAI1,XKR8,TRIM8,B9D2,NRBF2,RAPGEF2,DOCK5,RNF19B,STK17B,KLHL2,SLC6A6,PPP2R5A,HPSE,CDK19,PRCP,KBTBD2,NMI,SIPA1L1,SECTM1,TRIOBP,DYSF,ADIPOR1,EIF4EBP2,F2RL1,IFIH1,KLF7,RRAGD |
| 1.603e-06 | -13.34 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 191 | 53 | 17758 | 2588 |
GAA,MTM1,CDS2,ADD1,PPP1R12A,MPZL1,IQGAP1,NDC80,NOTCH2,CAMK1D,FAM101B,PRRG4,IRF2BPL,MARCH8,CD46,CPNE2,ADD3,METTL7A,ZFP36,PPP1CA,PHKA2,FLOT2,RPGR,S100A6,MYO5A,CERS2,DUSP1,PTPN18,TMEM43,NRBF2,SYNE2,VPS4B,STK17B,CYP4F3,USP6,ZMPSTE24,NUDT16,NUCB1,MPRIP,PRDX3,ATP7B,RAB11FIP1,FAM117A,CAB39,DYSF,ZBTB34,RELL1,MIIP,TOB1,DCBLD1,CAPN1,FAM45A,CD33 |
| 1.632e-06 | -13.33 | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | 196 | 54 | 17758 | 2588 |
LAMP1,GAA,LGALS3,S100A11,CTSB,HEBP1,ZCCHC24,BLVRB,HEXB,EFHD2,KCTD12,ARHGEF40,TSEN34,SIRPA,ARHGEF10L,GNS,APLP2,TIMP1,CST3,DAPK1,H2AFY,CTSD,PTPRE,SLC16A5,S100A6,CYP1B1,CPD,QSOX1,ALDH2,MAPKAPK3,PLAUR,S100A4,MPP1,SAT1,VAMP3,BLVRA,ASB13,CRISPLD2,TMEM164,ALDH3B1,SERPINA1,HPSE,ETS2,SECTM1,RAB31,NOD2,ZDHHC7,CTSA,PLXND1,PLIN3,ZMIZ1,SLC27A3,SLC31A2,RRAGD |
| 1.658e-06 | -13.31 | JEON_SMAD6_TARGETS_DN | MSigDB lists | JEON_SMAD6_TARGETS_DN | 19 | 12 | 17758 | 2588 |
IRS2,TOP2A,CENPA,USH1C,CDH1,KIF23,NOTCH3,ERBB3,CCNB2,KIF11,EGFR,CTH |
| 1.660e-06 | -13.31 | single organism signaling | biological process | GO:0044700 | 5196 | 876 | 16441 | 2455 |
DOC2A,ADD1,IL15RA,GRIK2,TRIM5,DNAJC3,RET,XIAP,NRG2,IL18,BAIAP3,SYTL4,CA8,SPSB1,CARD10,GRM5,TP73,CALM2,DAPK2,ZYX,RGS12,ARHGAP42,PSMD1,TGFBR3,DNM2,CLDN4,CRY2,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,IL10RB,TIPARP,NEK4,TNIP1,CDA,TFAP2C,KDELR3,PRKAR2B,ARF4,LCP1,ABR,PGF,CARHSP1,PLCG1,DNM1L,LIMK1,MYLK,MAP3K11,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,ARF6,HSPB1,STARD13,GAB1,SCN5A,NUAK1,SEC61G,ITGA6,SOX9,RAB23,ZNRF3,GPSM2,MERTK,HPCAL4,LMNA,TFAP4,RAC2,MEGF8,FLRT3,FAM13B,RANBP1,MAP3K9,MYDGF,PANX2,CNGA1,MAPK7,NCAM1,DGKG,NUP85,PAQR7,MAPKAPK3,SALL4,STAT4,ERO1A,SHARPIN,FHL2,CALCRL,NPHP3,ILK,ELK1,PSMA4,GNA11,RHOB,STK17A,PTPRF,IL1R1,NCOA3,FNTA,HTT,SEMA4D,ITPR1,OSMR,STK39,GDF11,NDE1,ARPC2,TRPC3,NUP58,RPS6KA3,DOCK9,DMPK,ARHGAP11A,NQO1,LFNG,CD82,INPP5D,PKP2,IL13RA1,MAPK4,NUF2,GRK6,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,TAX1BP3,RTKN2,ARL4D,DLG3,RASGEF1A,RAB27B,SCN3A,MX1,SEC61B,RIPK2,FZD4,RAB38,GIGYF1,IRS2,SLC9A6,AXL,WFS1,CORO1C,SIPA1L1,WWTR1,INPP4B,TRABD2A,RGS14,ARNT,MAPK12,CTHRC1,TNRC6C,NKX3-1,TAOK2,HSP90B1,MPZL1,TRAF2,SDC4,RASSF7,CCM2,FLOT1,BTN3A1,PDIA3,PKN1,PLPPR4,ZNF219,KCNC4,IFT27,NFAT5,ICAM1,SGPL1,CTNNBIP1,DIRAS3,ANK1,PDCD10,IRAK1,ITGB8,KNDC1,MCF2L,GPC3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,HCN3,AMOTL2,CTNNAL1,BCL9,RAPGEF2,PIK3R1,GRIN1,NEURL1B,SKA1,TXK,CNTNAP1,KIAA0141,ACVRL1,NR1D2,SYT7,RAB11FIP2,NR4A3,SSNA1,CENPE,ITGAV,NUP37,CD81,FOXA1,MYL9,SIGIRR,UNC93B1,BCAM,TNK1,EPAS1,AGRN,EPHA4,NDC80,NDRG2,DNAJB11,F11R,TEX2,ITPR2,PDGFB,SDC1,SPTB,RPS6KA2,NUP210,CTNNB1,SHC3,IL6ST,ARL1,MITF,PSMC2,DUSP10,TNFRSF18,NTN4,SCARA3,THRB,PLK1,KCNIP3,MCTP1,MARK1,CELSR2,CR2,EZR,ARFRP1,VCP,RHEB,PLEKHB1,OPTN,TRIM9,PLCH1,KCNMB4,WIPI1,CTNND1,KPNA2,PIK3C2B,TC2N,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,RASA2,HLA-F,PDCL,PSMD7,RACGAP1,CNTNAP2,NCKAP1,RAB6A,DOCK11,FBLN1,DHRS3,IL18R1,ANO1,BMP2,RB1,VASP,IGF1R,KIF13B,PAK2,SELK,MDFIC,PIM1,NTN1,WNT3A,PLCB2,PSMA5,DPYSL5,PCDH1,RGMB,CORO2A,STRADB,TCF7,SCRIB,PDK3,IFIT3,CDK5R1,NMT2,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,LTBP2,PLD1,SEMA3A,IFI6,RNF146,KCNAB3,NF2,FOXM1,TP53,DGKA,P2RX7,RHPN2,CCDC68,ERBB2,RASGRP3,STIL,BCAP31,SYTL2,IER3,CDK14,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,OAS3,NOTCH3,SCN2A,CTDSP2,DVL2,CTH,SULF2,SIRT1,CLCN3,MBP,AKT1,CDC20,PTGER4,MYL12A,DUOX1,DNAJC10,ATP1A1,IDE,PTPRJ,RBL1,PTK7,STK38,PSMD3,MAOA,EFNA5,IRF7,ANXA9,SYT13,ARHGAP4,ZMAT1,PINK1,CPEB4,ADGRG1,TAB3,CTSB,DAP,GNAL,MCTP2,ERCC6L,CDCA8,GABRG2,PSMD10,GDF15,JAG2,CRABP2,AIP,FZD6,IL22RA1,PPP2R3A,DNAJB9,NRP2,M6PR,CDK16,SGK1,IL17RA,TRIM21,BUB1,CPLX1,TSPAN13,SYK,CAMK2G,DUSP1,DLGAP1,P2RX4,HES1,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,AMFR,LITAF,PPARA,MAML2,PELI3,AKAP3,BBS2,BCAR1,MAPK8IP1,DGKE,CD83,PRDX4,BCL10,DDAH1,FAT4,SCG2,TWSG1,NMI,FGF18,E2F1,PKD2,ICOSLG,NDFIP1,ARHGEF9,PTGES,ZBTB33,ARHGEF4,LAMP1,ACVR1,TXN,LGR4,HSPG2,KLC2,CUL1,GATA3,PSME1,PDGFRL,PLXNA1,PJA2,SLC20A1,CENPN,NCS1,PICK1,PAK6,CTGF,ELMO2,IL31RA,PIK3CA,KCNS3,ATRNL1,IRF2,TACSTD2,RCAN3,TFG,METAP2,ACVR1C,CASP9,BNIP3L,AGO4,AURKB,SAV1,ZFAND5,ULK2,RAB2B,SGPP1,AREG,TBX1,PLK2,SH2D3C,NKD1,MAPK13,EIF4EBP2,UNC5B,TRAF5,F2RL1,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,PRKAA1,AKAP17A,NOTCH2,SLC1A3,APBA1,TNFRSF19,TSPAN7,MESDC2,CALR,ITGA3,RALGPS2,PIK3AP1,CYR61,PPP4R1,PRKG1,OPN3,DAPK1,MSH2,SORL1,OSTF1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,MAST4,SYTL3,GPR161,EEF1D,RIMS2,SOCS5,GFPT1,PRODH,KCNJ12,B9D2,MICB,CALM1,AMER1,DCHS1,ANO6,EPHA1,CYFIP2,KDM3A,ANTXR1,STX3,RASA1,PDE11A,FAS,DGKH,GABRD,PRKAG2,PELI2,CSNK1G1,MPP2,PIAS2,ARAP1,APPL2,CABIN1,NR4A2,EFNA1,MAP3K5,IFIH1,IRF1,SPRED1,REPS2,TCTN2,TRIP10,S100A11,RALBP1,THRA,RPS6KA1,IQGAP1,NDRG1,BCL2L1,EGR3,CD274,DDR1,FLT3,GNB2,EPS8L2,ZFYVE9,NOV,APLP2,CCNA2,RALB,DOK4,CDKN1B,DAB2IP,EPHB4,IFIT1,PDE4D,TSPAN1,LGMN,MED30,NR2C1,SEMA3B,DOCK4,DMTN,PRKCQ,ATP1B1,PYGO1,ASB13,CBL,ITPR3,ALCAM,FZD7,EPHA10,FYN,JAK1,PPP2R5A,NGFRAP1,STK26,TSPAN18,KIAA1804,STAT1,PPP1CB,SLC27A1,RAB29,NRG1,NR3C2,PRKAR1A,ARHGEF3,IGFBP6,DEPDC1,CENPI,EPS8,ARL4C,HERC5,GPR180,PLD2,SPDL1,FGF19,EFNB1,LGALS3BP,TEAD3,ADGRB2,HLA-A,CKAP5,RND1,RASSF8,E2F7,GNB5,PTEN,FJX1,FUT8,PRC1,CD9,SGK3,SLC44A2,ERBB3,MAP3K7,CITED2,CNPY3,TRIM62,SPRY2,NCOA2,MSH6,FARP2,RASGRF1,TGIF1,PDGFC,CASK,ALDH2,ARHGEF28,ZWINT,ARAP2,MPP1,FURIN,DIAPH2,YES1,FOS,GPLD1,RGS9,FGFR2,RIN3,RYK,RABL6,GRIN2D,LRRK1,GPER1,FZD5,MELK,RGMA,CCNC,LTBP1,CASP3,CAMKK1,UBE2Q1,KIF2C,CACNB4,DNER,KREMEN1,TRIM68,PTCHD4,SH3KBP1,HTR1D,EPCAM,ZFYVE16,RAB15,ZCCHC12,DPYSL2,TSPAN6,SIVA1,DLG1,AKR1B1,RAB20,CTTN,MYH14,PTPRE,IL1RAP,RASGRP1,CYP1B1,SOD1,CXXC5,TRIM8,CENPA,ITCH,USP18,ARHGDIB,ROR1,ADRBK2,STK17B,EDNRA,CXXC4,MDK,GPRC5B,KCNK1,MADD,CAB39,ADIPOR1,RAP1GAP,NRGN,APBA2,PPP2R5D,PSMC1,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,PPP1R12A,ETV5,ASB9,ATP6V1E2,CALM3,TEC,PHLPP1,DUSP5,NOXA1,CA2,LRRN2,KCNN4,OCRL,DIAPH2-AS1,PRKCI,FNIP1,KNTC1,HLA-C,NPTN,C10orf54,ZRANB1,GAD1,CCDC88A,MDFI,ELK3,PDE5A,EGFR,RHPN1,GNAS,BCAR3,ONECUT1,TSC1,INSR,PLPP3,NFKBIA,RAB31,RHOBTB2,NXPH4,YOD1,JAK3,TOB1,RARG,COL16A1,DRD1,SORBS1,SPC25,IL15,SLC2A8,PSME2,SOD2,PDIA5,IL27RA,MRAS,EXT2,ARHGEF16,SS18,ARTN,KIF14,SMO,GOT1,DIXDC1,NFKB2,F2R,PDIA6,FRS3,CHP1,MAP3K3,BAG4,KREMEN2,PTPRU,ERBB2IP,CD40,DUSP4,DOCK5,CDC25C,CASP4,MAP3K6,ARHGAP35,SOCS3,ALDH5A1,STAT6,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,PLXND1,SGOL1,ABCA1,LIFR,SORT1,ARHGEF11,ARHGEF7,CIT,LRP4,TGFBR1,AES,NOTUM,ITGA2B,XPR1,HMGXB4,SYDE2,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,ZDHHC13,BRD7,IQGAP3,MYO5A,SYPL1,RAB3B,ADAM17,CENPC,WNT10B,DEPDC4,NR4A1,NDRG3,FOXL1,LEPR,ARHGAP24,CTSL,HLA-B,CD8A,CASP7,RND3,RAP2C,UBE2D2,DTX4,UACA,ARRB1,GEM,ATP6V1C1,SOX8,L1CAM,AHR,CD33,SNPH,NGEF |
| 1.662e-06 | -13.31 | GRUETZMANN_PANCREATIC_CANCER_UP | MSigDB lists | GRUETZMANN_PANCREATIC_CANCER_UP | 350 | 84 | 17758 | 2588 |
MYL9,LTBP1,ACVR1,S100A11,TRIP10,GNPDA1,IQGAP1,RALBP1,NDRG1,TAP1,DGKA,DHX8,SDC1,EMP2,RCN1,APLP2,SCNN1A,CCNA2,RALB,LMO4,PLCG2,LGMN,FLOT2,GM2A,GPX4,CKS2,LAMP2,SEC23A,SOD1,CD55,PTPN9,LOXL2,ITPR3,MYL12A,CASP4,LCP1,DPYSL3,KDSR,PTGS2,FYN,ACYP1,AREG,KCNK1,MYLK,STAT1,KLF5,RAP1GAP,DLAT,GRN,PCOLCE,GOLIM4,EPS8,SLC1A3,CRABP2,DUSP5,TOP2A,ITGA3,CTSC,CALD1,PAK2,CD9,CKS1B,SORL1,PSMA5,RHOA,MMD,PLAUR,CRIP2,PARP4,PYGL,EMP3,SERTAD2,TIMP3,SERPINA1,PLOD2,SPINT2,RAB31,ATP1B3,GEM,UBE2C,AFAP1,MELK,ACOT7,ABCG1 |
| 1.667e-06 | -13.30 | STEIN_ESRRA_TARGETS_UP | MSigDB lists | STEIN_ESRRA_TARGETS_UP | 366 | 87 | 17758 | 2588 |
GAS2L1,ACACB,TRIM2,CEP70,UGP2,EPAS1,RPS6KA1,TMX4,APOO,SOD2,NDRG2,PRSS22,TEX2,NANS,ISOC2,MGST2,ECI1,CYP1A1,METTL7A,TACC2,MITF,TRPC1,STEAP3,GOT1,NFU1,MANF,EGLN3,PXMP4,SULT2B1,GM2A,PPIF,KIAA0040,CASP9,HTATIP2,ARFRP1,ATP1B1,PDHX,SEC14L2,GABARAPL1,FASTKD1,SLC25A4,ACYP1,WIPI1,ZNF165,RAP1GAP,PPP2R2D,LIFR,DLAT,FAM134B,GDF15,GMCL1,IFT27,SCML1,PDCD10,CTSC,KCNN4,NECAB3,FDXR,OPN3,FAM63A,ECI2,ALDH3A2,DUSP1,TRAK2,NAGPA,OPLAH,PGM1,UBAC1,PCTP,SPTLC2,MAP1B,EPN3,NUCB1,TJP3,ETS2,FA2H,ACADSB,TIMM8A,SLC25A40,SLC2A6,OTUB2,AURKA,MDH1,ACADM,PLIN3,HOOK1,EGLN1 |
| 1.674e-06 | -13.30 | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | 206 | 56 | 17758 | 2588 |
SLC25A24,MRC2,LGALS3,ST14,ATP8A1,FXYD3,ESRP1,SOX9,HDAC11,HAL,GMPR,GATA3,SDC1,PHLDA1,SRPX2,ANO1,SLC25A35,EPDR1,EPCAM,SPP1,MLPH,CDH1,GRHL1,CYR61,ELF5,TMEM51,TNFRSF12A,IGFBP2,TACSTD2,RAB27B,SLC12A2,GM2A,NFE2L3,FADS2,TGIF1,CD55,SLC39A8,TFAP2C,CDK1,MAPK8IP1,EDNRA,IRX3,GABARAPL1,SOX13,CARHSP1,ETS2,SHROOM3,NGFRAP1,PLK2,BMP1,LRRK1,COL16A1,GAB1,FOXA1,PROM2,DLAT |
| 1.690e-06 | -13.29 | response to endogenous stimulus | biological process | GO:0009719 | 1545 | 295 | 16441 | 2455 |
ACVR1,TRIM24,SSH1,NRG2,GATA3,PSME1,TP73,CALM2,ZYX,SESN3,PSMD1,TGFBR3,CTGF,KLF3,FOSB,STEAP2,PIK3CA,DNM2,CLDN4,PPP1CA,PIK3CD,ACVR1C,CASP9,AGO4,PRKAR2B,POR,PIAS3,ENPP1,PLCG1,AREG,TBX1,NOD2,HDAC1,EIF4EBP2,GAB1,KLF2,INPPL1,DGKQ,SOX9,PRKAA1,TFAP4,CALR,ITGA3,MEGF8,FLRT3,NCAM1,MAPK7,PAQR7,EPB41L5,CALM1,FHL2,ELK1,KDM3A,PSMA4,RASA1,FAS,MMP15,IL1R1,NCOA3,FNTA,PRKAG2,ITPR1,AURKA,NR4A2,TRPC3,EHD1,SPRED1,SLC2A4,NQO1,THRA,IQGAP1,WDTC1,EGR3,BCL2L1,PRKACA,GNB2,ZFYVE9,CCND1,CCNA2,ACAP2,CDH1,CDKN1B,DAB2IP,PDE4D,RASGEF1A,NR2C1,RIPK2,DMTN,PRKCQ,CBL,ITPR3,IRS2,FYN,JAK1,WWTR1,STAT1,PPP1CB,SLC27A1,NRG1,NR3C2,PRKAR1A,HSP90B1,TNRC6C,NKX3-1,ETS1,FGF19,ICAM1,CAPN2,IRAK1,OXCT1,PTEN,CST3,FUT8,BAX,CD9,TMBIM6,IGFBP2,ERBB3,CITED2,MAP3K7,SPRY2,NCOA2,HCN3,RASGRF1,PDGFC,TGIF1,SHMT1,RAPGEF2,PIK3R1,GRIN1,FURIN,YES1,FOS,GPLD1,PITX2,BTG1,RGS9,TIMP3,PLOD2,FGFR2,ACVRL1,NR1D2,NR4A3,GRIN2D,GPER1,ARSB,CD81,CPEB2,FOXA1,RGMA,CCNC,CASP3,UGT8,F11R,ITPR2,SDC1,PDGFB,SPTB,ZFYVE16,CTNNB1,ZCCHC12,SHC3,DPYSL2,PSMC2,ABCA2,AKR1B1,ASH2L,ARNT2,RASGRP1,THRB,SOD1,CITED4,EZR,IDH1,RHEB,MDK,MAP2,CAB39,ADIPOR1,PSMC1,NR2C2,RRAGD,GRN,PRKAA2,RUNX2,RASA2,PSMD7,ATP6V1E2,CALM3,PHLPP1,DUSP5,CORO1B,BMP2,SPP1,IGF1R,CA2,TIMP1,COL6A1,PRKCI,C10orf54,PSMA5,RGMB,STRADB,EGFR,FECH,GNAS,TSC1,INSR,PHLPP2,NFKBIA,SH3BP4,RAB31,LTBP2,JAK3,RARG,COL16A1,DRD1,GAS2L1,SORBS1,FOXM1,PSME2,SLC2A8,TP53,P2RX7,ERBB2,RASGRP3,PDGFA,ATP6V0B,SRR,GOT1,FRS3,SIRT1,BAG4,TIMP2,AKT1,PTPRU,ERBB2IP,DAG1,CASP4,SOCS3,PTGS2,DUOX1,ATP1A1,IDE,RBL1,PSMD3,SPTBN5,LTA4H,ABCA1,ANXA3,SORT1,CPEB4,CTSB,SERPINB9,LRP4,GNAL,PSMD10,SELL,GABRG2,GDF15,TGFBR1,HDAC9,ADRBK1,BMP7,TOX2,KLF9,SYK,MYO5A,CAMK2G,DUSP1,GCNT1,P2RX4,RHOA,ADAM17,WNT10B,PSMB4,NR3C1,NR4A1,GCLC,PPARA,GGH,RUNX3,BBS2,BCAR1,CTSL,TWSG1,CTSV,FGF18,E2F1,PKD2,HOXB13,ATP6V1C1,PLOD3,TBC1D4,ABCG1 |
| 1.713e-06 | -13.28 | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | 576 | 125 | 17775 | 2585 |
MFSD3,TNK1,ACVR1,SLC25A13,RPS6KA1,RET,DGKA,ETNK1,TP53,ERBB2,PDGFRL,GRK6,BAIAP3,PRKACA,FLT3,DDR1,SPTB,APPBP2,CDK14,WEE1,MUC16,RPS6KA2,PQLC2,CTNNB1,PAPSS1,DLG1,PIK3CA,SEMA3G,EPHB4,PIK3CD,TFG,DLG3,MYT1,SCYL3,FRS3,SEPHS1,MYO5B,NEK4,MAP3K3,SMARCA2,RFK,AKT1,CAPN6,PBK,ATP1B1,AURKB,PRKRA,MAP3K6,LCP1,FYN,FASTKD1,JAK1,CDK19,PLK2,PTK7,STK38,AXL,MYLK,MADD,MAP3K11,PRKCDBP,MAPK13,PIK3C2B,KLF5,PDXK,LIFR,HOXC13,MAPK12,PRKAR1A,PINK1,MRC2,CDK17,GNE,FAM134A,DOCK11,NEO1,RB1,CEP97,IGF1R,IRAK1,CDK16,PFKL,PTEN,MGAT4A,DAPK1,MAP3K9,CKS1B,SGK1,MAPK11,KNTC1,PIM1,ERBB3,PIKFYVE,MAPK7,MAP3K7,SYK,CAMK2G,SUN2,CASK,B3GNT2,USP31,ADCK3,PIK3R1,PIP4K2C,ZKSCAN2,AK4,MAML2,EIF2AK1,YES1,PDK3,EGFR,MAPK8IP1,DCAF10,MAPKAPK2,BTG1,FGFR2,CCDC6,DCK,DYSF,AURKA,MAP3K5,JAK3,TBC1D4,RPS6KA3,DMPK |
| 1.742e-06 | -13.26 | tube development | biological process | GO:0035295 | 573 | 127 | 16441 | 2455 |
HECA,ACVR1,GRHL2,LGR4,EPAS1,ST14,THRA,RET,EPHA4,GATA3,CCNB1,SDC1,PRKACA,STIL,TP73,PDGFA,EPCAM,CYP1A1,SETDB2,CTNNB1,CTGF,NPNT,DACT1,LMO4,DLG1,SMO,AKR1B1,TWIST1,TACSTD2,DAB2IP,PDE4D,PPP1CA,ETV4,DVL2,THRB,ASXL1,TFAP2C,SAV1,DAG1,EDNRA,IRX3,ARHGAP35,HS6ST1,AREG,SHROOM3,PTK7,TBX1,TRAF3IP1,STAT1,KLF5,PLXND1,LTA4H,COBL,PCSK5,CTHRC1,KLF2,NKX3-1,SERPINE2,TMTC3,ITGA6,MAN1A2,SDC4,CCM2,SOX9,RAB23,CTSZ,GPSM2,NCKAP1,FZD6,GBX2,CTNNBIP1,BMP2,RB1,TNS3,VASP,ITGA3,GATA2,MEGF8,GPC3,BMP7,BAX,TMBIM6,MAP3K7,WNT3A,NTN1,CITED2,SLC12A2,SPRY2,REC8,EPB41L5,TGIF1,HES1,ADAMTS2,PDGFC,FMN1,SALL4,DCHS1,RC3H2,PRICKLE1,SCRIB,KIF20B,NPHP3,ILK,FOXL1,NFIB,CRISPLD2,EGFR,BCL10,NCOA3,TSC1,FAT4,FGFR2,ACVRL1,CSF1,FGF18,TBX18,SPINT2,NR4A3,PKD2,GDF11,PLOD3,OSR1,SOX8,SHOX2,RARG,FOXA1,ADAMTS16 |
| 1.743e-06 | -13.26 | RODRIGUES_NTN1_TARGETS_DN | MSigDB lists | RODRIGUES_NTN1_TARGETS_DN | 153 | 45 | 17758 | 2588 |
BIN1,PRSS8,KLF2,GAA,SIGIRR,BCAM,PACSIN2,USH1C,PAPSS2,HSPG2,SOX9,ARL4C,FBXO2,PLA2G16,NFAT5,IER3,VASP,ADORA1,ITGA3,RRBP1,PIK3CA,CLDN4,MYH14,C10orf54,RAB27B,RBMS2,PCDH1,KIFC2,NR4A1,HTATIP2,KLK6,CBL,STK17B,SOX13,MMP15,TNS4,PGF,TIMP3,AREG,PVRL2,LIMK1,MYLK,CANT1,CDK18,DMPK |
| 1.869e-06 | -13.19 | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | 187 | 52 | 17758 | 2588 |
BIN1,SIGIRR,HECA,ALDH6A1,HAPLN3,GALNT12,TRAF2,EPHA4,MORC4,GATA3,AES,ANO9,C3orf18,PHF1,EPS8L2,LYSMD4,TMEM63A,ZNF75D,BDH1,TMEM143,FXYD5,ANKRD12,TRPC1,KIF22,WWP1,PIM1,FAM84B,MAST4,RASGRP1,CAMK2G,SUSD3,CASK,SLC39A8,STMN3,ESYT1,ITPR3,NPDC1,NMT2,PRIM1,OPTN,PLCG1,ATP1A1,AMMECR1,LRIG1,FAM117A,SFMBT1,CAB39,TTC39C,SLC25A38,ST3GAL1,CBX7,DOCK9 |
| 1.869e-06 | -13.19 | GSE3982_BCELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_BCELL_VS_BASOPHIL_DN | 187 | 52 | 17758 | 2588 |
MRC2,ACVR1,REPS2,ATP2C2,OSGIN2,PBX3,COX6C,CA8,MAP1LC3B,FLT3,SIRPA,PSMD1,CYP1A1,FRY,RIMS3,OSBPL3,CST3,KLF3,DRAM1,CD9,SORL1,FAR2,MYRIP,DUSP1,PDGFC,MBP,FOXJ2,MPP1,PARP4,CDA,MTRF1L,PCTP,SGPP1,SOX13,PIAS3,FUCA1,SFXN1,GNAS,PPP2R5A,ETS2,SEMA4D,H1F0,DBI,RAB31,ZDHHC7,EFNA1,CHPT1,RTN3,TOB1,PTGES,JARID2,RRAGD |
| 1.872e-06 | -13.19 | AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 | MSigDB lists | AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 | 103 | 34 | 17758 | 2588 |
BIN1,ACACB,DNAJB2,DGKA,PDGFRL,ITPR2,B4GALT4,KCTD9,NEO1,CCDC92,ADD3,CTGF,LLGL2,NECAB3,PASK,TRPC1,TAX1BP3,ACOX2,CDKN2D,CAMK2G,SEMA3B,OLFML2A,CELSR2,NR3C1,SNTB2,WHSC1,CYP4F3,GNA11,SERPINA1,DHTKD1,HSPB1,ZNF701,RRAGD,FAM134B |
| 1.894e-06 | -13.18 | ZHANG_TLX_TARGETS_60HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_60HR_UP | 288 | 72 | 17758 | 2588 |
SORBS1,HSPG2,NQO1,S100A11,FAM129B,THRA,HEXB,TAP1,LMCD1,GMPR,TMEM19,SEPT4,MAP1LC3B,LTBP3,PDGFA,SIPA1L2,AOX1,TAX1BP3,LGMN,PTPRE,S100A13,SULF2,TIMP2,TMEM43,S100A4,SAT1,NFE2L1,TCN2,GABARAPL1,TRIM47,WIPI1,WWTR1,BMP1,APBA2,CPPED1,GRN,CPEB4,CYP2J2,ARL4C,SEPP1,PARM1,SIRPA,DOPEY2,SPP1,RALGPS2,CST3,BAX,OPN3,PLEKHF1,RFX5,CITED2,CTSD,TTLL1,EPHX1,IGDCC4,PDGFC,ELK3,PRSS23,PQLC3,NR4A1,FOS,NDRG3,TP53INP2,FUCA1,SCARB2,BTG1,TMEM50B,SLC6A6,CSF1,SLC4A3,PER3,TOB1 |
| 1.900e-06 | -13.17 | MORI_IMMATURE_B_LYMPHOCYTE_DN | MSigDB lists | MORI_IMMATURE_B_LYMPHOCYTE_DN | 90 | 31 | 17758 | 2588 |
HMMR,CENPA,TXN,DLGAP5,TUBB4B,CDC20,CDCA3,NUSAP1,CCNB1,H2AFV,CDK1,PRDX4,CKAP5,PRIM1,CDKN2C,TOP2A,PCNA,CCNA2,DCK,CDCA5,PRC1,NEK2,CKS1B,KPNA2,IQGAP3,RAG1,UBE2C,CCNB2,E2F8,MELK,SMC4 |
| 1.905e-06 | -13.17 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | 192 | 53 | 17758 | 2588 |
CDK17,GOLIM4,PARP12,TTC39B,VANGL1,TMX4,ARFGEF1,TDRKH,BAIAP3,B4GALT4,SPSB1,LGALS3BP,NEO1,CA2,CDH1,SHC3,IMPAD1,MGAT4A,ZDHHC23,MDFIC,C10orf54,PACSIN1,TIPARP,GCNT1,CPD,POU6F1,SUN2,ELK3,TIMP2,MFI2,IFITM3,COQ10B,RC3H2,LITAF,STMN3,PRICKLE1,RAB3IP,CD40,FNDC3A,IRX3,CD8A,NAAA,TMEM50B,RAB11FIP2,PHLPP2,LRIG1,ITPR1,PPM1H,SERPINI1,ATP1B3,GLCCI1,AHR,ABCA1 |
| 1.905e-06 | -13.17 | GSE27786_LSK_VS_LIN_NEG_CELL_UP | MSigDB lists | GSE27786_LSK_VS_LIN_NEG_CELL_UP | 192 | 53 | 17758 | 2588 |
MFSD3,KIF3C,NFKBIE,PARP14,FLOT1,KCTD12,HMGN3,SORBS3,HDAC6,NFAT5,CCND1,KIAA1107,PIK3AP1,ELMO2,FDXR,POLL,SLC44A2,BRI3,OAS3,PLCB2,DGKG,ODF2L,CTDSP2,CRTAP,SGCE,CAMSAP3,AKT1,B9D2,ADCK3,LRRC66,CAPNS1,ZFAND5,SPNS3,DAG1,MUM1L1,CMTM7,FOXD2,NUDT16,PAFAH1B3,AGPAT2,H1F0,HOXA9,HAGHL,TDRD7,CSGALNACT1,ERAP1,GLB1,VSIG10,TANC2,TMEM159,LSM14B,NRBP1,TMEM173 |
| 1.905e-06 | -13.17 | GSE29618_MONOCYTE_VS_PDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_UP | 192 | 53 | 17758 | 2588 |
LGALS3,IL15,S100A11,HEBP1,CAST,HLA-F,BLVRB,SOD2,ASAH1,CALM3,EFHD2,FAM198B,OAT,ARHGEF40,SIRPA,IER3,CALM2,CAPN2,APLP2,FAM46A,TIMP1,BCL6,RAB20,MTMR11,ALDH3A2,CKAP4,CYP1B1,PPIF,TIMP2,S100A4,CALM1,BNIP3L,PYGL,ARHGDIB,BLVRA,RNF19B,CRISPLD2,RHOB,KLHL2,IRS2,ALDH3B1,SLC6A6,SERPINA1,HPSE,C19orf66,RCBTB2,RAB31,NOD2,ZDHHC7,KLF11,SLC31A2,CD33,PCSK5 |
| 1.984e-06 | -13.13 | REACTOME_SIGNALLING_BY_NGF | MSigDB lists | REACTOME_SIGNALLING_BY_NGF | 212 | 57 | 17758 | 2588 |
CASP3,ARHGEF3,ARHGEF11,RPS6KA1,CALM3,ITPR2,PHLPP1,PRKACA,ARHGEF16,CALM2,RPS6KA2,IRAK1,ADRBK1,PTEN,SHC3,RALB,PRKCI,PIK3CA,DNM2,CDKN1B,MAPK11,MAPK7,TIAM1,RASGRF1,ADAM17,RHOA,RIPK2,AKT1,MAPKAPK3,NR4A1,CASP9,PIK3R1,CALM1,FURIN,PRKAR2B,DUSP4,ELK1,ITPR3,CDK1,ABR,MAPKAPK2,IRS2,PLCG1,NGFRAP1,NFKBIA,HDAC1,MAPK13,ARHGAP4,PPP2R5D,ARHGEF9,RPS6KA3,NGEF,MAPK12,ARHGEF4,FGD1,PRKAR1A,PCSK5 |
| 1.998e-06 | -13.12 | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | 6320 | 1024 | 17775 | 2585 |
HECA,IBTK,GRIK2,AK7,PNPLA2,HEXB,RET,CCNO,BAIAP3,DPP8,SNX9,LTBP3,GRM5,MUC4,DNM2,CRY2,PPP1CA,TMEM37,RNF26,TIAM1,IL10RB,TIPARP,CCDC74A,NEK4,TMEM98,PNKD,ABR,MPRIP,MID1IP1,ATP7B,CELF5,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,STARD13,HSPB1,ANXA11,GGA1,ATG4A,FLII,FRY,FLRT3,FBXO7,RANBP1,FBXL14,PCYOX1,USP1,USP38,FAM84B,ALPK1,CNGA1,PANX2,MAPK7,ZMYM1,MOXD1,DGKG,NUP85,HPS3,PQLC3,SHARPIN,KIF20B,ELK1,NPHP3,SFXN5,GNA11,CACHD1,FNTA,SLC4A4,OSCP1,TMEM173,RUSC1,ADAMTS16,WDR63,RHBDL3,C5orf30,FAM91A1,REPS1,APPBP2,ST5,CDH1,SH3BP1,ENPP5,ZNF365,MYT1,TMEM200B,SNX8,COL6A2,C6orf1,RIPK2,AGPS,HTATIP2,DNAJB14,TANC1,GIGYF1,PDLIM3,SHROOM3,CDK19,CORO1C,AXL,PNPLA6,SLC25A30,MAPK12,HSP90B1,CKAP2,CCM2,OSGIN2,CTSZ,NFAT5,DIRAS3,ZFX,SLC25A45,ITGB8,IGSF9,KNDC1,TUBGCP6,FAM102A,IGFBP2,RAG1,ADAMTS2,PLSCR1,PIK3R1,MRS2,PGBD1,CNTNAP1,RAB11FIP2,SYT7,FBXO44,ITGAV,CMPK2,SRSF9,PHC1,CCNI,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,TEX2,GALM,MGAT5B,ITPR2,SPTB,PLS3,SUSD2,NUP210,TM9SF2,CTNNB1,PAPSS1,MITF,TMEM143,ABCA2,NTN4,PLK1,MARK1,CELSR2,CR2,CCBL2,SESN1,DZIP1L,KDM4D,TRIM9,TNS4,TRAM2,KLF12,PARP12,RUNX2,USH1C,DNAJB2,RASA2,PSMD7,RAB6A,NCKAP1,FBLN1,MYO5C,TNS3,UBE2Q2,RINL,ICAM5,AHCY,PIM1,FAR2,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,USP31,ZNF320,SCRIB,PRX,NMT2,C18orf8,RASGRP2,KBTBD2,P4HA3,NLRC5,PLD1,SEMA3A,CDAN1,RAD21,HOXB7,TP53,RHPN2,P2RX7,PCBP1,STIL,SYTL2,TTC21B,WDR44,TACC2,BCL6,ZDHHC23,NOTCH3,SULF2,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,XRCC3,EFNA5,BIN1,PINK1,CDH22,KLHL13,TAB3,CTSB,GNAL,HAL,ERI2,GDF15,AIP,NRP2,DNAJB9,SH2D4A,CD109,ALPP,LYPD6,UBE2J1,SGK1,FAM134C,DUSP1,NFE2L3,P2RX4,RHOA,COL7A1,DGKE,USP6,BCL10,DDX23,CNOT2,SMTNL2,SCG2,NEIL3,SH3BGRL2,HIPK3,ARHGEF9,GOLGB1,PNISR,LGR4,HSPG2,VANGL1,C1orf198,CUL1,PDGFRL,PJA2,SLC9A7,CYP1A1,ANKS6,FOSB,SERINC2,PIK3CA,KCNS3,IRF2,HYLS1,METAP2,SGCE,RAB2B,PPP2R4,LRIG1,BMP1,PRDM5,MAPK13,CCDC97,TBC1D1,TMEM55B,PRKAA1,TNFRSF19,PDXDC1,PSIP1,SH3RF2,MESDC2,DOPEY2,VASN,AIM1,MSH2,DAPK1,PRKG1,ADCK2,TPST1,CACNA1D,C8orf58,DLX4,KCTD3,SYTL3,ZNF117,TRAK2,SOCS5,SPATA20,PRODH,KCNJ12,PRSS23,CEP89,ADCK3,PYGL,NPC2,ANTXR1,MMP15,NT5C2,PLEKHH2,TJP3,C1orf21,MPP2,FAM83D,APPL2,ARAP1,AGBL5,CABIN1,PER3,HOOK1,IFIH1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,RALBP1,THRA,ATP2C2,FLT3,ZFYVE9,CD46,APOBEC3B,NOV,RALB,BRI3,EPHB4,OSBPL7,FLOT2,CLSTN1,UTRN,PKMYT1,ATP1B1,CBL,ITPR3,ALCAM,ACAD10,CCDC149,HAGHL,COBL,MAMDC2,DEPDC1,HAPLN3,EPS8,CBLL1,EFHD2,HERC5,PLD2,DNAH3,COX7A2,CKAP5,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,ERBB3,CITED2,SLC16A5,MSH6,FARP2,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,DIAPH2,AIF1L,FOS,CDK5RAP1,CRTC2,FGFR2,ABCB1,WDR91,FZD5,ESPL1,MELK,DEF6,UGT8,MPP5,TRIM68,EPCAM,RAB15,SIPA1L2,CDKL5,CASC4,SIVA1,ANKFN1,CTTN,MYRIP,CYP1B1,CXXC5,LAP3,USP18,ITCH,RGAG1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SH3GLB2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,PYROXD2,ETV5,ADAMTSL4,QSOX2,PFKL,COL6A1,SRP54,LIMCH1,BRAT1,C10orf54,ZRANB1,ETV7,GAD1,SLC12A2,SNX7,ELK3,PDE5A,KIAA1109,NUBP1,C3orf58,STEAP1,INSR,SH3BP4,DONSON,SHROOM2,JAK3,RARG,DRD1,LMO7,SORBS1,HDAC11,SOD2,COL18A1,MXD1,SAP130,CYP4F11,KIF14,ZBTB49,EPB41L4B,ETHE1,SEPHS1,SOAT1,PTPRU,TMTC2,HSF4,STAT6,SECTM1,TLE1,RCAN2,ABCA1,GLIS3,ENO2,TSPAN15,SHPRH,TGFBR1,COL4A5,SBF1,HMGXB4,TMEM63A,KIF5B,CARD8,TAF1B,LLGL2,A4GALT,MYCL,BMP7,TOX2,RRBP1,H2AFY,ARVCF,KANK2,CLIP2,MYO5A,RBMS2,PGM1,DCAF6,WNT10B,SYBU,RC3H2,FAM73B,NDRG3,LEPR,FOXL1,LEMD2,RND3,FIBCD1,ZMIZ1,AHR,ABCG1,NGEF,ACACB,KLK10,ADD1,TRIM5,AASS,FBXO2,CACNA2D2,SMARCAL1,LYNX1,CNTROB,EPDR1,DAPK2,CALM2,WEE1,TGFBR3,RGS12,DNAH6,ALDH1A3,FUT1,TUBG1,PIK3CD,APOBEC3G,ODF2L,NWD1,SERTAD4,RNF11,MTRF1L,LOXL2,CYP4F3,COL12A1,DNM1L,LIMK1,MYLK,ARF6,TMTC3,CYP2J2,SOX9,MERTK,ELF3,DNPEP,PRICKLE4,FAM13B,ZIC5,STT3B,C9orf72,KIF20A,SALL4,MYBL2,PLS1,MEST,SPTLC2,RHOB,DHX32,STK17A,PTPRF,SCARB2,HTT,SETD3,DYSF,AURKA,OSMR,ARPC2,DRP2,ZNF502,CSRP2,EGLN1,ARHGAP11A,PAPSS2,GRHL2,ETNK1,WDTC1,APC2,PRKACA,TNFSF9,ZNF385B,UHRF1BP1L,CDS1,SCNN1A,RNF220,SP100,RTKN2,SCN3A,ENPP4,SSH3,FZD4,SYNE2,PLEKHO1,CDCA2,RAB38,IRS2,SLC9A6,PLEKHG1,INPP4B,ARNT,TAOK2,FARP1,ANO9,KCNC4,ICAM1,PDIA4,NEO1,ANK1,IRAK1,FAM160A2,CTSC,CALD1,KCNK5,MAPK11,ITM2C,TPCN1,HCN3,AMOTL2,CTNNAL1,RAPGEF2,ELOVL3,MYEOV,PLEKHA7,GRIN1,GALNT3,KIAA0141,ACVRL1,NR1D2,ZFP30,FHL1,CENPE,DCBLD1,MYL9,TRIM2,AGRN,PPM1J,CUL4B,EPHA4,MCCC1,NDC80,FHDC1,HDAC6,MKRN3,DDHD2,TLN2,CCDC38,ZNF462,ING1,MCTP1,ESYT1,ANLN,IDH1,VCP,RHEB,DPYSL3,PLCH1,MFAP3L,TBC1D17,MAP2,DOLPP1,PRKCDBP,PIK3C2B,EPB41L4A,PRKAA2,ASAH1,RACGAP1,CNTNAP2,DOCK11,B4GALT4,PGAP1,IL18R1,RB1,DAZAP1,IGF1R,EXOC8,MDFIC,ALDH3A2,ABCC1,CHSY3,WDR72,KBTBD8,TCF7,EIF2AK1,IFIT3,ANKRD29,MAPKAPK2,ITGA7,LTBP2,UPF3B,UGP2,NF2,FOXM1,XYLT1,DGKA,ERBB2,LPIN3,CYP26A1,RAD23A,PER2,LHX6,PLCG2,GYS1,FAR1,DVL2,SIRT1,TMTC1,TCEB2,CDC20,MYL12A,DUOX1,DNAJC10,PSMD3,ADAMTS14,ZBTB6,LTA4H,NDST3,ZC3HC1,MAN2B2,GOLIM4,RUSC2,GNE,GABRG2,JAG2,SLC9A2,PPP2R3A,GBX2,CEP97,MAGEE1,ABCD1,KLF9,SLC45A3,CAMK2G,FAH,NR3C1,CCDC34,AKAP3,BCAR1,MAPK8IP1,CDKN2AIPNL,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,TMC5,CDCA7L,FAM117A,CLIP4,TBC1D4,NDFIP1,SAT2,SUN1,GAA,ACVR1,PPP4R4,TTC39B,FAM129B,ATP8A1,TMEM41B,KLC2,PPFIBP2,PLXNA1,SLC20A1,CTGF,ELMO2,STEAP2,AOX1,ATRNL1,MTMR11,RCAN3,SNTB2,HSPA12A,TNS1,AURKB,SLC17A5,SLC25A5,TP53I3,KDSR,SFXN1,RBM47,GNPTAB,NKD1,FAM110C,UNC5B,LZTS1,RTN3,DLAT,DDX58,MRPL44,FRMD4A,C6orf106,KIF23,NDUFA4,NOTCH2,SLC1A3,MECOM,ITGA3,SLC16A6,NECAB3,BDH1,RUNDC3B,SORL1,CTSD,PIKFYVE,TMED2,RIMS2,IGSF3,DNAI1,EPB41L5,QSOX1,DDB2,MMD,ZNF84,TBC1D8B,ANO6,PTPRH,AMER1,TMEM133,PKM,KDM3A,GLT8D2,RASA1,DGKH,NAB2,SLC4A3,PCDH19,FGD6,NR4A2,MAP3K5,PKD1L2,IRF1,PLEKHG3,SLC2A4,CEP70,NLRX1,TRIP10,RPS6KA1,SUZ12,CAST,IQGAP1,SNN,NUDT12,GNB2,MNS1,ZNF75D,CDKN1B,CNNM4,PHKA2,LGMN,MYO5B,SLC5A11,CDKN2AIP,TEP1,COX11,SLC11A2,C15orf39,H2AFV,SP4,NIN,EPHA10,OSBPL2,FYN,JAK1,STAT1,KIAA1804,PPP1CB,KLF5,HS3ST3B1,ATMIN,MRPS9,WASF3,PCOLCE,ANKRD13D,ARHGEF3,JRKL,ARL4C,CCNJL,APOBEC3H,SPR,PNPLA5,LGALS3BP,SIX4,AKIRIN1,FAM111A,OXCT1,PTEN,CENPJ,SGK3,SLC44A2,ATP8B1,SPRY2,SMC4,RASGRF1,ARAP2,SHMT1,DENND1B,LRRC1,NUCB1,MAMDC4,CTNS,PRDX3,CSTF2,ARSB,NCAPG2,SLC25A38,ESYT2,EXPH5,LTBP1,HEBP1,KIF2C,TAF6L,TMC1,KREMEN1,SH3KBP1,ARHGEF10L,C7orf49,LRRC6,CAPG,DLG1,AKR1B1,POF1B,ARNT2,SLC39A10,ATL1,SYNE3,CXXC4,ARHGEF19,ZNF114,APBA2,PPP2R5D,LRRFIP2,ATP6V1E2,ZNF432,CA2,LRRN2,RFX5,ALS2CL,PARD3B,GYLTL1B,RNF113A,EGFR,XKRX,BCAR3,GNAS,TSC1,NUDT16,NFKBIA,ALPK3,PITPNA,PROM2,ZSWIM5,FAM92A1,SLC2A8,MORC4,TDRKH,ZMYND10,MICALL2,SLC25A48,SETDB2,KHNYN,FRYL,SMO,STEAP3,RPN2,LOXL1,PDIA6,SCYL3,HSPA2,MAP3K3,GCA,TAF5,ERBB2IP,DUSP4,KCTD2,BFSP1,BHLHB9,CANT1,PLXND1,AKNA,SGOL1,CBX4,SORT1,FRMD6,LRP4,FAM134A,IRF2BPL,KIAA0319,BRD7,IQGAP3,SUN2,ADAM17,ASPM,GCLC,NR4A1,SPAG1,MAP1B,KLHL2,HLA-B,PRCP,ATP6V1C1,GEM,L1CAM,LRRC57,SNPH |
| 2.033e-06 | -13.11 | lamellipodium | cellular component | GO:0030027 | 167 | 48 | 17570 | 2579 |
WASF3,ARAP3,INPPL1,NF2,SSH1,ARHGEF7,FLOT1,NCKAP1,APC2,CORO1B,RAC2,VASP,CDH1,CTNNB1,MCF2L,PIK3CA,DNM2,ACTA2,CTTN,FLOT2,SCYL3,CCDC88A,RHOA,SYNE2,SPATA13,SCRIB,RAB3IP,ILK,BCAR1,ANTXR1,DAG1,STX3,DPYSL3,KLHL2,PLCG1,TSC1,SWAP70,PLEKHH2,CORO1C,MYLK,FGD6,DYSF,PKD2,ITGAV,PLXND1,PIEZO1,NRBP1,FGD1 |
| 2.128e-06 | -13.06 | transitional_cell_carcinoma | COSMIC cancer mutations | transitional_cell_carcinoma | 6322 | 1024 | 17775 | 2585 |
HECA,IBTK,GRIK2,AK7,PNPLA2,HEXB,RET,CCNO,BAIAP3,DPP8,SNX9,LTBP3,GRM5,MUC4,DNM2,CRY2,PPP1CA,TMEM37,RNF26,TIAM1,IL10RB,TIPARP,CCDC74A,NEK4,TMEM98,PNKD,ABR,MPRIP,MID1IP1,ATP7B,CELF5,FAM114A1,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,STARD13,HSPB1,ANXA11,GGA1,ATG4A,FLII,FRY,FLRT3,FBXO7,RANBP1,FBXL14,PCYOX1,USP1,USP38,FAM84B,ALPK1,CNGA1,PANX2,MAPK7,ZMYM1,MOXD1,DGKG,NUP85,HPS3,PQLC3,SHARPIN,KIF20B,ELK1,NPHP3,SFXN5,GNA11,CACHD1,FNTA,SLC4A4,OSCP1,TMEM173,RUSC1,ADAMTS16,WDR63,RHBDL3,C5orf30,FAM91A1,REPS1,APPBP2,ST5,CDH1,SH3BP1,ENPP5,ZNF365,MYT1,TMEM200B,SNX8,COL6A2,C6orf1,RIPK2,AGPS,HTATIP2,DNAJB14,TANC1,GIGYF1,PDLIM3,SHROOM3,CDK19,CORO1C,AXL,PNPLA6,SLC25A30,MAPK12,HSP90B1,CKAP2,CCM2,OSGIN2,CTSZ,NFAT5,DIRAS3,ZFX,SLC25A45,ITGB8,IGSF9,KNDC1,TUBGCP6,FAM102A,IGFBP2,RAG1,ADAMTS2,PLSCR1,PIK3R1,MRS2,PGBD1,CNTNAP1,RAB11FIP2,SYT7,FBXO44,ITGAV,CMPK2,SRSF9,PHC1,CCNI,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,TEX2,GALM,MGAT5B,ITPR2,SPTB,PLS3,SUSD2,NUP210,TM9SF2,CTNNB1,PAPSS1,MITF,TMEM143,ABCA2,NTN4,PLK1,MARK1,CELSR2,CR2,CCBL2,SESN1,DZIP1L,KDM4D,TRIM9,TNS4,TRAM2,KLF12,PARP12,RUNX2,USH1C,DNAJB2,RASA2,PSMD7,RAB6A,NCKAP1,FBLN1,MYO5C,TNS3,UBE2Q2,RINL,ICAM5,AHCY,PIM1,FAR2,MPHOSPH9,DPYSL5,PCDH1,PLEKHA6,USP31,ZNF320,SCRIB,PRX,NMT2,C18orf8,RASGRP2,KBTBD2,P4HA3,NLRC5,PLD1,SEMA3A,CDAN1,RAD21,HOXB7,TP53,RHPN2,P2RX7,PCBP1,STIL,SYTL2,TTC21B,WDR44,TACC2,BCL6,ZDHHC23,NOTCH3,SULF2,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,IDE,PTPRJ,ABHD12,RBL1,XRCC3,EFNA5,BIN1,PINK1,CDH22,KLHL13,TAB3,CTSB,GNAL,HAL,ERI2,GDF15,AIP,NRP2,DNAJB9,SH2D4A,CD109,ALPP,LYPD6,UBE2J1,SGK1,FAM134C,DUSP1,NFE2L3,P2RX4,RHOA,COL7A1,DGKE,USP6,BCL10,DDX23,CNOT2,SMTNL2,SCG2,NEIL3,SH3BGRL2,HIPK3,ARHGEF9,GOLGB1,PNISR,LGR4,HSPG2,VANGL1,C1orf198,CUL1,PDGFRL,PJA2,SLC9A7,CYP1A1,ANKS6,FOSB,SERINC2,PIK3CA,KCNS3,IRF2,HYLS1,METAP2,SGCE,RAB2B,PPP2R4,LRIG1,BMP1,PRDM5,MAPK13,CCDC97,TBC1D1,TMEM55B,PRKAA1,TNFRSF19,PDXDC1,PSIP1,SH3RF2,MESDC2,DOPEY2,VASN,AIM1,MSH2,DAPK1,PRKG1,ADCK2,TPST1,CACNA1D,C8orf58,DLX4,KCTD3,SYTL3,ZNF117,TRAK2,SOCS5,SPATA20,PRODH,KCNJ12,PRSS23,CEP89,ADCK3,PYGL,NPC2,ANTXR1,MMP15,NT5C2,PLEKHH2,TJP3,C1orf21,MPP2,FAM83D,APPL2,ARAP1,AGBL5,CABIN1,PER3,HOOK1,IFIH1,TCTN2,REPS2,DLGAP5,ST14,CCDC110,RALBP1,THRA,ATP2C2,FLT3,ZFYVE9,CD46,APOBEC3B,NOV,RALB,BRI3,EPHB4,OSBPL7,FLOT2,CLSTN1,UTRN,PKMYT1,ATP1B1,CBL,ITPR3,ALCAM,ACAD10,CCDC149,HAGHL,COBL,MAMDC2,DEPDC1,HAPLN3,EPS8,CBLL1,EFHD2,HERC5,PLD2,DNAH3,COX7A2,CKAP5,WWP2,RASSF8,E2F7,TMEM87B,RNF128,FUT8,ERBB3,CITED2,SLC16A5,MSH6,FARP2,ALDH2,LONRF3,ZC3H11A,ZKSCAN2,DIAPH2,AIF1L,FOS,CDK5RAP1,CRTC2,FGFR2,ABCB1,WDR91,FZD5,ESPL1,MELK,DEF6,UGT8,MPP5,TRIM68,EPCAM,RAB15,SIPA1L2,CDKL5,CASC4,SIVA1,ANKFN1,CTTN,MYRIP,CYP1B1,CXXC5,LAP3,USP18,ITCH,RGAG1,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,TDRD7,SH3GLB2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,PYROXD2,ETV5,ADAMTSL4,QSOX2,PFKL,COL6A1,SRP54,LIMCH1,BRAT1,C10orf54,ZRANB1,ETV7,GAD1,SLC12A2,SNX7,ELK3,PDE5A,KIAA1109,NUBP1,C3orf58,STEAP1,INSR,SH3BP4,DONSON,SHROOM2,JAK3,RARG,DRD1,LMO7,SORBS1,HDAC11,SOD2,COL18A1,MXD1,SAP130,CYP4F11,KIF14,ZBTB49,EPB41L4B,ETHE1,SEPHS1,SOAT1,PTPRU,TMTC2,HSF4,STAT6,SECTM1,TLE1,RCAN2,ABCA1,GLIS3,ENO2,TSPAN15,SHPRH,TGFBR1,COL4A5,SBF1,HMGXB4,TMEM63A,KIF5B,CARD8,TAF1B,LLGL2,A4GALT,MYCL,BMP7,TOX2,RRBP1,H2AFY,ARVCF,KANK2,CLIP2,MYO5A,RBMS2,PGM1,DCAF6,WNT10B,SYBU,RC3H2,FAM73B,NDRG3,LEPR,FOXL1,LEMD2,RND3,FIBCD1,ZMIZ1,AHR,ABCG1,NGEF,ACACB,KLK10,ADD1,TRIM5,AASS,FBXO2,CACNA2D2,SMARCAL1,LYNX1,CNTROB,EPDR1,DAPK2,CALM2,WEE1,TGFBR3,RGS12,DNAH6,ALDH1A3,FUT1,TUBG1,PIK3CD,APOBEC3G,ODF2L,NWD1,SERTAD4,RNF11,MTRF1L,LOXL2,CYP4F3,COL12A1,DNM1L,LIMK1,MYLK,ARF6,TMTC3,CYP2J2,SOX9,MERTK,ELF3,DNPEP,PRICKLE4,FAM13B,ZIC5,STT3B,C9orf72,KIF20A,SALL4,MYBL2,PLS1,MEST,SPTLC2,RHOB,DHX32,STK17A,PTPRF,SCARB2,HTT,SETD3,DYSF,AURKA,OSMR,ARPC2,DRP2,ZNF502,CSRP2,EGLN1,ARHGAP11A,PAPSS2,GRHL2,ETNK1,WDTC1,APC2,PRKACA,TNFSF9,ZNF385B,UHRF1BP1L,CDS1,SCNN1A,RNF220,SP100,RTKN2,SCN3A,ENPP4,SSH3,FZD4,SYNE2,PLEKHO1,CDCA2,RAB38,IRS2,SLC9A6,PLEKHG1,INPP4B,ARNT,TAOK2,FARP1,ANO9,KCNC4,ICAM1,PDIA4,NEO1,ANK1,IRAK1,FAM160A2,CTSC,CALD1,KCNK5,MAPK11,ITM2C,TPCN1,HCN3,AMOTL2,CTNNAL1,RAPGEF2,ELOVL3,MYEOV,PLEKHA7,GRIN1,GALNT3,KIAA0141,ACVRL1,NR1D2,ZFP30,FHL1,CENPE,DCBLD1,MYL9,TRIM2,AGRN,PPM1J,CUL4B,EPHA4,MCCC1,NDC80,FHDC1,HDAC6,MKRN3,DDHD2,TLN2,CCDC38,ZNF462,ING1,MCTP1,ESYT1,ANLN,IDH1,VCP,RHEB,DPYSL3,PLCH1,MFAP3L,TBC1D17,MAP2,DOLPP1,PRKCDBP,PIK3C2B,EPB41L4A,PRKAA2,ASAH1,RACGAP1,CNTNAP2,DOCK11,B4GALT4,PGAP1,IL18R1,RB1,DAZAP1,IGF1R,EXOC8,MDFIC,ALDH3A2,ABCC1,CHSY3,WDR72,KBTBD8,TCF7,EIF2AK1,IFIT3,ANKRD29,MAPKAPK2,ITGA7,LTBP2,UPF3B,UGP2,NF2,FOXM1,XYLT1,DGKA,ERBB2,LPIN3,CYP26A1,RAD23A,PER2,LHX6,PLCG2,GYS1,FAR1,DVL2,SIRT1,TMTC1,TCEB2,CDC20,MYL12A,DUOX1,DNAJC10,PSMD3,ADAMTS14,ZBTB6,LTA4H,NDST3,ZC3HC1,MAN2B2,GOLIM4,RUSC2,GNE,GABRG2,JAG2,SLC9A2,PPP2R3A,GBX2,CEP97,MAGEE1,ABCD1,KLF9,SLC45A3,CAMK2G,FAH,NR3C1,CCDC34,AKAP3,BCAR1,MAPK8IP1,CDKN2AIPNL,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,TMC5,CDCA7L,FAM117A,CLIP4,TBC1D4,NDFIP1,SAT2,SUN1,GAA,ACVR1,PPP4R4,TTC39B,FAM129B,ATP8A1,TMEM41B,KLC2,PPFIBP2,PLXNA1,SLC20A1,CTGF,ELMO2,STEAP2,AOX1,ATRNL1,MTMR11,RCAN3,SNTB2,HSPA12A,TNS1,AURKB,SLC17A5,SLC25A5,TP53I3,KDSR,SFXN1,RBM47,GNPTAB,NKD1,FAM110C,UNC5B,LZTS1,RTN3,DLAT,DDX58,MRPL44,FRMD4A,C6orf106,KIF23,NDUFA4,NOTCH2,SLC1A3,MECOM,ITGA3,SLC16A6,NECAB3,BDH1,RUNDC3B,SORL1,CTSD,PIKFYVE,TMED2,RIMS2,IGSF3,DNAI1,EPB41L5,QSOX1,DDB2,MMD,ZNF84,TBC1D8B,ANO6,PTPRH,AMER1,TMEM133,PKM,KDM3A,GLT8D2,RASA1,DGKH,NAB2,SLC4A3,PCDH19,FGD6,NR4A2,MAP3K5,PKD1L2,IRF1,PLEKHG3,SLC2A4,CEP70,NLRX1,TRIP10,RPS6KA1,SUZ12,CAST,IQGAP1,SNN,NUDT12,GNB2,MNS1,ZNF75D,CDKN1B,CNNM4,PHKA2,LGMN,MYO5B,SLC5A11,CDKN2AIP,TEP1,COX11,SLC11A2,C15orf39,H2AFV,SP4,NIN,EPHA10,OSBPL2,FYN,JAK1,STAT1,KIAA1804,PPP1CB,KLF5,HS3ST3B1,ATMIN,MRPS9,WASF3,PCOLCE,ANKRD13D,ARHGEF3,JRKL,ARL4C,CCNJL,APOBEC3H,SPR,PNPLA5,LGALS3BP,SIX4,AKIRIN1,FAM111A,OXCT1,PTEN,CENPJ,SGK3,SLC44A2,ATP8B1,SPRY2,SMC4,RASGRF1,ARAP2,SHMT1,DENND1B,LRRC1,NUCB1,MAMDC4,CTNS,PRDX3,CSTF2,ARSB,NCAPG2,SLC25A38,ESYT2,EXPH5,LTBP1,HEBP1,KIF2C,TAF6L,TMC1,KREMEN1,SH3KBP1,ARHGEF10L,C7orf49,LRRC6,CAPG,DLG1,AKR1B1,POF1B,ARNT2,SLC39A10,ATL1,SYNE3,CXXC4,ARHGEF19,ZNF114,APBA2,PPP2R5D,LRRFIP2,ATP6V1E2,ZNF432,CA2,LRRN2,RFX5,ALS2CL,PARD3B,GYLTL1B,RNF113A,EGFR,XKRX,BCAR3,GNAS,TSC1,NUDT16,NFKBIA,ALPK3,PITPNA,PROM2,ZSWIM5,FAM92A1,SLC2A8,MORC4,TDRKH,ZMYND10,MICALL2,SLC25A48,SETDB2,KHNYN,FRYL,SMO,STEAP3,RPN2,LOXL1,PDIA6,SCYL3,HSPA2,MAP3K3,GCA,TAF5,ERBB2IP,DUSP4,KCTD2,BFSP1,BHLHB9,CANT1,PLXND1,AKNA,SGOL1,CBX4,SORT1,FRMD6,LRP4,FAM134A,IRF2BPL,KIAA0319,BRD7,IQGAP3,SUN2,ADAM17,ASPM,GCLC,NR4A1,SPAG1,MAP1B,KLHL2,HLA-B,PRCP,ATP6V1C1,GEM,L1CAM,LRRC57,SNPH |
| 2.132e-06 | -13.06 | Phosphatidylinositol signaling system | KEGG pathways | hsa04070 | 98 | 34 | 6908 | 1076 |
MTM1,CDS2,INPPL1,INPP5D,TMEM55B,DGKQ,DGKA,CALM3,ITPR2,CDIPT,CDS1,CALM2,INPP5E,PTEN,OCRL,IMPAD1,PLCG2,PIK3CA,PIK3CD,PIKFYVE,PLCB2,DGKG,CALM1,PIK3R1,PIP4K2C,ITPR3,DGKE,DGKH,PLCG1,PI4K2B,ITPR1,INPP4B,PIK3C2B,ITPKA |
| 2.132e-06 | -13.06 | Phosphatidylinositol signaling system | KEGG pathways | ko04070 | 98 | 34 | 6908 | 1076 |
MTM1,CDS2,INPPL1,INPP5D,TMEM55B,DGKQ,DGKA,CALM3,ITPR2,CDIPT,CDS1,CALM2,INPP5E,PTEN,OCRL,IMPAD1,PLCG2,PIK3CA,PIK3CD,PIKFYVE,PLCB2,DGKG,CALM1,PIK3R1,PIP4K2C,ITPR3,DGKE,DGKH,PLCG1,PI4K2B,ITPR1,INPP4B,PIK3C2B,ITPKA |
| 2.178e-06 | -13.04 | GSE25087_TREG_VS_TCONV_ADULT_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_ADULT_UP | 183 | 51 | 17758 | 2588 |
SLC25A24,IBTK,SSH1,FAM160B1,IQGAP1,SDC4,SOD2,GATA3,CBLL1,GALM,FAM91A1,BARD1,DUSP5,PLS3,RGS12,PIK3AP1,ANKS1B,RALB,SLC16A6,IQGAP3,MYBL1,TIPARP,CRTAP,MCCC2,ABCC1,GCNT1,CORO2A,S100A4,SNTB2,UTRN,ATP1B1,FRMD4B,OPTN,GLCE,GABARAPL1,IRS2,PIAS3,KDSR,FYN,CDK19,RBL1,RAB11FIP1,NR4A2,SAMD8,GLB1,TTC39C,GLCCI1,TRAF5,AHR,SNX30,FAM45A |
| 2.222e-06 | -13.02 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN | 159 | 46 | 17758 | 2588 |
WASF3,DLGAP5,CIT,LRP4,PTTG1,PBX3,KIF23,KIF2C,CRABP2,FANCI,CKAP5,TOP2A,APOBEC3B,SS18,PCNA,KIF14,ABCA2,PLK4,MSH2,CKS1B,RNASEH2A,MPHOSPH9,NR2C1,MSH6,SMC4,CKS2,FADS2,TAF5,SEPT6,CDC20,AURKB,ESYT1,KIF11,CDC25C,CDK1,FZD7,DDX23,PRIM1,COL13A1,HOXA9,AURKA,KPNA2,CCNB2,CBX5,ESPL1,MELK |
| 2.235e-06 | -13.01 | positive regulation of protein modification process | biological process | GO:0031401 | 1170 | 231 | 16441 | 2455 |
CCNC,TXN,ACVR1,TRIM5,CAMKK1,EPHA4,ARFGEF1,XIAP,CUL1,NRG2,PSME1,IL18,NENF,CCNB1,SEPT4,SNX9,PDGFB,ERP29,CARD10,SPTB,PHF1,GRM5,FANCI,TP73,CALM2,PAK6,PSMD1,CTNNB1,CTGF,NPNT,SHC3,IL6ST,PSMC2,IL31RA,PIK3CA,DLG1,TNFRSF18,SLC39A10,RASGRP1,PLK1,NEK4,SOD1,SPRTN,PRKAR2B,CDK1,VCP,PIAS3,PLCG1,GPRC5B,ANKRD6,TBX1,PPP2R4,MADD,NOD2,MAP3K11,PRKCDBP,CAB39,F2RL1,PSMC1,GAB1,PPP1R12A,DNAJB2,RASA2,SOX9,PRKAA1,PSMD7,CALM3,SORBS3,TEC,DUSP5,BMP2,IGF1R,CYR61,PAK2,MAP3K9,FNIP1,MDFIC,BRAT1,NPTN,MYDGF,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,MDFI,MMD,MAPKAPK3,CALM1,PDE5A,STRADB,ILK,PSMA4,EGFR,RASA1,CDK5R1,FAS,MAPKAPK2,BCAR3,FNTA,PRKAG2,INSR,SEMA4D,PELI2,PLPP3,CSF1,DCUN1D1,STK39,EFNA1,GDF11,MAP3K5,JAK3,CTBP1,XDH,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,FLT3,EMP2,STIL,PDGFA,CCND1,ST5,RALB,KIF14,BCL6,DAB2IP,RASGEF1A,F2R,HSPA2,DVL2,FRS3,CHP1,MAP3K3,SIRT1,TIMP2,PSRC1,BAG4,RIPK2,AKT1,FZD4,CDC20,CDCA2,CD40,MAP3K6,FZD7,IRS2,FYN,JAK1,PPP2R5A,STK26,PSMD3,WFS1,KIAA1804,SLC27A1,EFNA5,NRG1,SPTBN5,CNEP1R1,ARNT,PRKAR1A,PINK1,TAOK2,NKX3-1,TAB3,TRAF2,SDC4,FLOT1,PSMD10,TGFBR1,GDF15,PKN1,FGF19,ICAM1,PDCD10,ADORA1,IRAK1,PTEN,KNDC1,BMP7,BAX,BRD7,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,HES1,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,PRICKLE1,YES1,BCL10,GPLD1,BANK1,FGFR2,ACVRL1,FGF18,RAP2C,NMI,RYK,TADA2B,ARRB1,PPP2R3C,GRIN2D,PKD2,GPER1,LRRK1,CENPE,FZD5,CD81,NDFIP1,UBE2C,JARID2 |
| 2.236e-06 | -13.01 | embryo development | biological process | GO:0009790 | 943 | 192 | 16441 | 2455 |
EMX1,ACVR1,ADD1,HSPG2,EPAS1,RET,GATA3,PLAC1,CCNB1,PDGFB,PICK1,NPM2,CYP1A1,CTNNB1,IMPAD1,ALDH1A3,ELF5,DLG1,ARNT2,ZBTB18,SPEF2,SOD1,TFAP2C,ARFRP1,PRKRA,ICMT,ZFAND5,GINS4,COL12A1,ABR,EDNRA,IRX3,CXXC4,HS6ST1,PLCG1,TBX1,HOXA9,TRAF3IP1,LRIG1,HDAC1,TANC2,APBA2,GAB1,E2F8,MAFF,PCSK5,GRN,KLF2,RUNX2,USH1C,CDKN1C,SOX9,RAB23,RACGAP1,NCKAP1,APBA1,PGAP1,DUSP5,ELF3,MECOM,BMP2,VASP,ITGA3,CYR61,GATA2,FLRT3,MEGF8,FRAS1,OCRL,COL6A1,MSH2,NEK2,WNT3A,NTN1,TMED2,MDFI,CYP26B1,EPB41L5,SALL4,DCHS1,VEZT,SCRIB,KIF20B,NPHP3,EGFR,RASA1,G2E3,CDK5R1,GNAS,MMP15,TSC1,NCOA3,ETS2,HTT,ITGA7,PLPP3,EFNA1,CCNB2,SEMA3A,RARG,EGLN1,GRHL2,HOXB7,NF2,ST14,LFNG,THRA,WDTC1,TP53,OSR2,BCL2L1,PRKACA,STIL,EXT2,RCN1,PDGFA,SETDB2,DACT1,LMO4,PLK4,SMO,TWIST1,ECE1,ACSL4,DVL2,SULF2,AKT1,DUSP4,ARHGAP35,SOCS3,SHROOM3,PTK7,NRG1,COBL,ARNT,PRKAR1A,CTHRC1,TNRC6C,NKX3-1,LRP4,SDC4,CCM2,NES,TGFBR1,JAG2,CRABP2,HOXB2,EFNB1,SIX4,PPP2R3A,FZD6,GBX2,TOP2A,CAPN2,E2F7,MGAT1,BMP7,GPC3,FUT8,BAX,TFAP2A,ERCC2,MAP3K7,CITED2,GFI1,TTPA,SPRY2,DUSP1,TGIF1,PDGFC,HES1,UBE2A,PRICKLE1,COL7A1,BCL10,CNOT2,FGFR2,ACVRL1,TWSG1,SPINT2,TBX18,NR4A3,PKD2,ITGAV,PLOD3,FZD5,ZMIZ1,SOX8,OSR1,NCAPG2,SHOX2,FOXA1 |
| 2.236e-06 | -13.01 | liver | COSMIC cancer mutations | liver | 16979 | 2512 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,ZNF503-AS2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,RINL,FRAS1,KIF13B,ICAM5,TBCD,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,FOXO6,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,PLAC1,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,NR1D2,ACVRL1,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,NUP62CL,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,CITED4,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,TCEB2,S100A4,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,DGKQ,CALB2,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,GNB2,TMPRSS4,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,NKAIN3,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,SPC25,FAM92A1,ABCG4,TDRKH,ZMYND10,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,CMTM6,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,ATP5H,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,PSMA4,GNA11,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,RHBDL3,PTTG1,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,MZT1,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,IL22RA1,VPS26A,PARM1,SH2D4A,FZD6,NRP2,M6PR,CD109,C16orf74,ALPP,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,GPR107,CAPN12,DLGAP5,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,TSPAN18,FAM195A,SLC27A3,COBL,PRKAR1A,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,TMEM221,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,IL18,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,SMN1,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,SERPINB5,CCDC69,GRIN2D,ARSB,NCAPG2,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 2.254e-06 | -13.00 | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | MSigDB lists | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | 243 | 63 | 17758 | 2588 |
GRN,ENO2,IGFBP6,HSPG2,CD63,DAP,NDRG1,XYLT1,EPHA4,ETV5,EPS8,CACNA2D2,ERBB2,VASH1,DDR1,FBLN1,TSPAN7,PARM1,CDK14,DAPK2,CALR,BTG3,TGFBR3,ADORA1,CTGF,GNB5,ACTA2,TRPC1,VAT1,TAGLN2,MANF,ZNF365,CPE,S100A13,NEB,PLK1,QSOX1,SGCE,CELSR2,PRSS23,ASXL1,SLC39A8,STAT4,SAT1,SLC11A2,MAP1B,EDNRA,FRMD4B,DPYSL3,MDK,MAGED2,IL1R1,NUCB1,BTG1,TIMP3,FGFR2,KCNK1,MYLK,FAM114A1,UNC5B,PLOD3,CD81,AFAP1 |
| 2.259e-06 | -13.00 | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN | 193 | 53 | 17758 | 2588 |
DDX58,PARP12,IL15RA,IL15,PARP14,TRIM5,PSME2,CYP2J2,TAP1,GMPR,HERC5,SAMD9,FBXO6,HERC6,LGALS3BP,DTX3L,TYMP,SP100,PIK3AP1,MSH2,IFIT1,OAS3,LAMP3,PARP9,HMMR,REC8,MX1,ZWINT,PLSCR1,IFITM3,LAP3,USP18,UTRN,C1GALT1C1,BLVRA,IFIT3,SPTLC2,PSMA4,TCN2,SCARB2,PI4K2B,C19orf66,TRIM69,AXL,NMI,SECTM1,STAT1,TDRD7,IRF7,CMPK2,SLC31A2,IFIH1,IFI6 |
| 2.259e-06 | -13.00 | GSE29618_BCELL_VS_MDC_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DN | 193 | 53 | 17758 | 2588 |
GRN,TXN,CD63,NDRG1,CTSB,ARL4C,EFHD2,NDRG2,KCTD12,NDUFA4,IL18,IL13RA1,F11R,GSTP1,FLT3,IL18R1,LMNA,TIMP1,DPYSL2,CST3,RRBP1,CAPG,H2AFY,TIPARP,NAGA,S100A6,CCDC88A,PPIF,RFK,S100A4,PLEKHO1,ATP1B1,ILK,MYL12A,LCP1,PTGS2,DDOST,ETS2,PRCP,HOXA9,AXL,SPINT2,SH3BP4,RAB31,RAB11FIP1,ARRB1,ARPC2,NDFIP1,AHR,TOB1,CPPED1,CD33,PRKAR1A |
| 2.259e-06 | -13.00 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN | 193 | 53 | 17758 | 2588 |
GRN,PLA2G4A,SORT1,CDS2,TXN,IGFBP6,PSME2,BLVRB,APOO,SOD2,ERI2,MICALL2,DSE,SPR,DHRS3,IFT27,DUSP5,TSEN34,RCN1,TNS3,ATP6V0B,DNPEP,LMO4,AIM1,RAB20,SNX10,S100A13,CKAP4,CPD,VPS11,LAP3,PLAUR,CDA,PYGL,HMG20B,IFIT3,DAG1,STX3,ABR,INSR,DNM1L,P4HA2,SECTM1,SLC2A6,STAT1,RAB31,NETO2,IRF7,PLXND1,ATP1B3,GEM,SLC27A3,IRF1 |
| 2.259e-06 | -13.00 | HALLMARK_HEME_METABOLISM | MSigDB lists | HALLMARK_HEME_METABOLISM | 193 | 53 | 17758 | 2588 |
GCLM,BCAM,ADD1,ALDH6A1,CTSB,HEBP1,CAST,BLVRB,ABCG2,FAM46C,SPTB,BMP2K,RAD23A,ATG4A,MARCH8,ANK1,CA2,KHNYN,FBXO7,KLF3,MARCH2,MINPP1,IGSF3,TRAK2,TMCC2,LAMP2,CLCN3,ERMAP,NR3C1,GCLC,FOXJ2,MPP1,NFE2L1,BNIP3L,FBXO9,HTATIP2,SLC11A2,UBAC1,EIF2AK1,TNS1,BLVRA,OPTN,ENDOD1,DCAF10,FECH,CTNS,GDE1,H1F0,P4HA2,DCUN1D1,ADIPOR1,SLC25A38,RAP1GAP |
| 2.259e-06 | -13.00 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN | 193 | 53 | 17758 | 2588 |
DLGAP5,LGALS3,S100A11,GNPDA1,DAP,PTTG1,ASL,RHPN2,RACGAP1,MNS1,IL18R1,AIP,REPS1,HLA-A,CAPN2,DAPK2,CDKN2C,RAC2,KIF22,MDFIC,TMEM37,CTSD,SNX10,S100A13,S100A6,PQLC3,PLSCR1,SNTB2,S100A4,CRIP2,LITAF,CAPNS1,ARHGDIB,AURKB,PRRC1,DOCK5,RNF19B,CDK1,CASP4,PRDX4,GABARAPL1,GALNT3,CARHSP1,CASP7,JAK1,DBI,CTSA,GEM,ARF6,SGOL1,E2F8,ACOT7,XDH |
| 2.264e-06 | -13.00 | Ser/Thr_dual-sp_kinase | interpro domains | IPR002290 | 268 | 68 | 18293 | 2672 |
CAMKK1,RPS6KA1,MAPK4,CAMK1D,GRK6,PRKACA,CDK14,PAK6,DAPK2,RPS6KA2,CDKL5,PASK,PLK4,MAP3K3,NEK4,PLK1,MARK1,AKT1,PRKCQ,AURKB,MAP3K6,ADRBK2,STK17B,CDK1,ULK2,STK26,CDK19,PLK2,STK38,MYLK,MAPK13,MAPK12,PRKAA2,TAOK2,DYRK3,CDK17,NUAK1,CIT,PRKAA1,PKN1,ADRBK1,CDK16,PAK2,NEK2,PRKG1,DAPK1,SGK3,PRKCI,SGK1,MAPK11,PIM1,MAPK7,MAST4,PHKG2,CAMK2G,CASK,MAPKAPK3,PIM3,STK17A,MAPKAPK2,AURKA,STK39,CDK18,MAP3K5,HIPK3,RPS6KA3,MELK,DMPK |
| 2.272e-06 | -12.99 | Signaling by FGFR4 | REACTOME pathways | R-HSA-5654743 | 313 | 78 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,CBL,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.272e-06 | -12.99 | Signaling by FGFR3 | REACTOME pathways | R-HSA-5654741 | 313 | 78 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,CBL,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.288e-06 | -12.99 | GSE22886_NAIVE_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_DC_DN | 198 | 54 | 17758 | 2588 |
GAA,EPAS1,NQO1,ST14,BLVRB,CTSZ,KCTD12,MGST2,DSE,VASH1,SIRPA,M6PR,SNX13,ATP6V0B,PSMD1,TM9SF2,PPP1R10,SLC16A6,MITF,DAPK1,H2AFY,TFG,PTPRE,SYK,NAGA,CCDC88A,PPIF,LAMP2,DOCK4,GCA,ADAM17,ALDH2,GCLC,VAMP3,NFE2L1,ATP1B1,LHFPL2,ADRBK2,BCAR3,SLC6A6,RBM47,CTNS,RCBTB2,CORO1C,NR4A3,MAOA,GLB1,MDH1,GLA,ZMIZ1,PLIN3,NRGN,SLC31A2,SLC27A3 |
| 2.341e-06 | -12.96 | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | MSigDB lists | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | 300 | 74 | 17758 | 2588 |
CCNE2,CCNC,TMEM184B,UGP2,IBTK,FAM160B1,C5orf30,UBE2Z,RHPN2,SNN,PER2,SESN3,GRHL1,TACC2,RGS3,XYLT2,CNNM4,DUSP10,DAB2IP,SCN3A,CXXC5,MARK1,PTGER4,SERTAD3,LHFPL2,COL12A1,SGPP1,NFIX,TRAM2,RBM47,KLF2,CPEB4,CDKN1C,PPP1R12A,RAB23,GPR180,NFAT5,DNAJB9,WWP2,KIF5B,FRY,CDK16,GATA2,PIK3AP1,FAM13B,FNIP1,NPTN,PIKFYVE,MYLIP,SOCS5,TRAK2,TGIF1,PLEKHA6,DCAF6,PAPD7,TEF,FHL2,NFIB,BSDC1,TSC1,SERTAD2,PHLPP2,ITPR1,CDCA7L,NR4A3,PITPNA,STK39,GDF11,ITGAV,CEP41,CPEB2,TOB1,RAD21,DOCK9 |
| 2.383e-06 | -12.95 | DORN_ADENOVIRUS_INFECTION_32HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_32HR_DN | 39 | 18 | 17758 | 2588 |
NR4A1,FHL2,COL7A1,EGR3,SRSF5,CD83,IER3,CCND1,BCAR3,RND3,CYR61,PLK2,NFKBIA,SGK1,SERPINB5,TNFRSF12A,EFNA1,NFKB2 |
| 2.448e-06 | -12.92 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | 74 | 27 | 17758 | 2588 |
GCLM,ACVR1,GDF15,PIM3,C15orf39,MERTK,MAP1B,GABARAPL1,PGF,NCOA3,HS6ST1,ZFP36,NAB2,ANKRD12,SGK1,CCDC82,NRG1,SAMD8,ZBTB34,TIPARP,CLIP2,SPRY2,HIPK3,AHR,FGFR1OP2,NIPA1,DUSP1 |
| 2.504e-06 | -12.90 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN | 1705 | 314 | 17758 | 2588 |
ACACB,ACVR1,IBTK,IL15RA,VANGL1,SLC25A13,XIAP,LACTB2,CNTROB,MORF4L2,SNX9,CALM2,WEE1,SESN3,TGFBR3,RDH14,KLF3,ATP13A3,RCAN3,SMYD5,SMARCA2,SH3BGRL,PBK,BNIP3L,GALNT7,COL12A1,SLC44A3,SFXN1,HLF,MID1IP1,DNM1L,LIMK1,AGFG2,MRPS28,WBSCR27,ARF6,F2RL1,E2F8,GAB1,DLAT,DHPS,NOTCH2,PSIP1,KIAA1161,RABGGTA,TFAP4,SNX18,RANBP1,SLAIN2,USP1,MCCC2,PIGC,FADS2,PMPCB,B9D2,ADCK3,CALM1,ELK1,NFIB,FRMD4B,PTPRF,IL1R1,CACHD1,FAM64A,MTFMT,SLC4A4,TIMM8A,FAAH,ITPR1,SLC4A3,PIAS2,OSMR,DYSF,MAP3K5,PLIN3,PER3,SERPINB1,CBX5,DOCK9,EGLN1,ELK4,SPRED1,KIF3C,TCF25,GRHL2,DLGAP5,THRA,SUZ12,ACTR8,IL13RA1,NUF2,REPS1,KIAA1147,CDKN1B,BRI3,EPHB4,ACSL4,PHKA2,RAB27B,SULT2B1,NAGA,CAPN6,PANK1,CLSTN1,UTRN,TMEM144,NUSAP1,BCL7B,AKR1E2,TANC1,CBL,NFIX,AMZ2,FYN,NGFRAP1,ZNF704,ISOC1,TTC8,GALK1,FARP1,ATP9A,TRAF2,BACE1,MAN1A2,FLOT1,EFHD2,PLD2,FBXO6,ETS1,CKAP5,CTNNBIP1,RASSF8,ADD3,FJX1,FUT8,SLC44A2,PLEKHF1,IGFBP2,AK3,CNOT6L,CASD1,CASK,PLSCR1,BCL9,PIK3R1,VAMP3,YES1,GRTP1,KIF11,SKA1,CDK5RAP1,TIMP3,DGCR2,ATXN7L3,NR1D2,FAM3C,PLA2G15,RYK,CSTF2,ETAA1,OSR1,NCAPG2,JARID2,CCNI,LTBP1,TRIM2,ST13,CUL4B,EPHA4,ARFGEF1,ECI1,SH3KBP1,FANCI,ARHGEF10L,MAGOHB,CTNNB1,IL6ST,ELF5,PAPSS1,PASK,SLC44A1,DLG1,RP2,CTTN,BTBD3,CYP1B1,TDP1,FOPNL,ITCH,CBX6,ROR1,ANLN,ZBTB7B,SESN1,TBC1D17,KCNK1,MAP2,IARS2,PRKCDBP,EPB41L4A,NR2C2,RUNX2,ZNF395,CALM3,RACGAP1,VASP,DAZAP1,IGF1R,PFKL,SLC30A6,LIMCH1,BRAT1,MDFIC,CCDC88A,KDELR1,ABCC1,MDFI,HP1BP3,ELK3,VWA1,ZSCAN12,KIAA1109,NUBP1,ZDHHC3,FECH,PVRL2,H1F0,SPAG7,RHOBTB2,PLD1,KLF7,RAD21,SLC25A24,NF2,FOXM1,CTDSPL,SOD2,GMPR,ERBB2,SLC7A2,EMP2,PER2,RAD23A,IER3,EFR3A,TACC2,FRYL,PLK4,GYS1,STEAP3,GOT1,MINPP1,FAR1,CTDSP2,FRS3,RFK,FIGNL1,SERTAD3,ERBB2IP,DOCK5,IDE,PAFAH1B3,RBL1,STAT6,EFNA5,RPL22,LTA4H,ST3GAL1,CTDSP1,FAM134B,BIN1,GOLIM4,TSPAN15,RUSC2,DAP,FRMD6,ERCC6L,ERI2,CHAC2,TRIB2,LBR,XPR1,NRP2,HMGXB4,ZNF212,KIF5B,C16orf74,TOP2A,CDK16,RRBP1,UBE2J1,KANK2,IQGAP3,FAIM,CLIP2,TLE6,CAMK2G,GCNT1,P2RX4,ADAM17,MOSPD2,NR3C1,POLD3,BBS2,CNOT2,SWAP70,NEIL3,CDCA7L,PPP2R3C,SPCS3,ICOSLG,CEP41,NDFIP1,UBE2C |
| 2.572e-06 | -12.87 | extracellular region part | cellular component | GO:0044421 | 3764 | 642 | 17570 | 2579 |
KLK10,IL15RA,DNAJC3,HEXB,FBXO2,NRG2,IL18,LYNX1,SNX9,CMTM6,LTBP3,GRM5,EPDR1,CALM2,NAPG,PSMD1,TGFBR3,MUC4,CABP1,ALDH1A3,DNM2,SEMA3G,PPP1CA,TINAGL1,IL10RB,CPE,MGAT5,TUBA4A,SH3BGRL,DSTN,RNF11,PRKAR2B,LOXL2,F12,ARF4,LCP1,COL12A1,ENPP1,CARHSP1,MYLK,SERPINB6,ARF6,HSPB1,ANXA11,ALDH6A1,CYP2J2,ITGA6,RAB23,MERTK,TTYH3,GNS,SH3D21,RAC2,DNPEP,CD22,ATP5H,MEGF8,FLRT3,PCYOX1,MYDGF,NCAM1,ULBP2,C9orf72,PLS1,MEST,PSMA4,GNA11,RHOB,CYB5A,PTPRF,IL1R1,NAAA,SCARB2,NCOA3,SLC4A4,SEMA4D,APMAP,DYSF,MDH1,MAL2,B4GAT1,GDF11,ARPC2,CFAP20,SERPINB1,XDH,ADAMTS16,MTM1,NQO1,TUBB4B,LFNG,CD82,APOO,MVB12B,PRKACA,TNFSF9,MUC16,SCNN1A,CDH1,TAX1BP3,ACSL4,DLG3,RAB27B,ENPP4,COL6A2,LGALS8,FZD4,SYNE2,CYS1,VPS4B,SNX12,ALDH3B1,AXL,PDXK,GEN1,ISOC1,GALK1,CTHRC1,HSP90B1,MAN1A2,SDC4,FLOT1,PDIA3,CTSZ,NUCB2,GSTP1,SRPX2,ICAM1,CAPN2,CXCL16,PDCD10,FUT2,ITGB8,CTSC,ARSG,GPC3,MCF2L,MGAT4A,CST3,TUBGCP6,BAX,ADAM15,WWP1,IGFBP2,ITM2C,S100A6,CRTAP,PVRL4,ADAMTS2,PLSCR1,DUSP23,PLEKHA7,AK4,BLVRA,CRISPLD2,GALNT3,RPL12,PROM1,PLOD2,SYT7,DBI,FAM3C,PLA2G15,ITGAV,CD81,CYBRD1,ACOT7,BCAM,AGRN,GNPDA1,CUL4B,LMCD1,NDRG2,F11R,NENF,GALM,PDGFB,SDC1,SLC9A3R2,SUSD2,CPNE2,PCNA,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,SLC44A1,RBBP8NL,NTN4,NEB,S100A13,THRB,CD55,CR2,EZR,ERP44,KLK6,IDH1,CDK1,VCP,RHEB,DPYSL3,KDM4D,ARRDC1,CTNND1,MYL12B,PRSS8,LGALS3,FXYD3,PSMD7,ASAH1,RACGAP1,RAB6A,NCKAP1,FBLN1,ANO1,CORO1B,MYO5C,BMP2,VASP,TIMP1,FRAS1,AHCY,TMEM8A,NTN1,WNT3A,ALDH3A2,CKAP4,PSMA5,ABCC1,PCBP3,SCRIB,MAPKAPK2,EPN3,PVRL2,CSF1,PRPS2,FAM213A,LTBP2,ATP1B3,SEMA3A,UGP2,P3H2,CTDSPL,PCBP1,C1orf116,SDF4,PDGFA,EFR3A,PLCG2,VAT1,OAS3,MINPP1,LMAN1,GM2A,SULF2,CTH,CPD,TIMP2,TCEB2,FIGNL1,S100A4,ACO1,MYL12A,C3orf33,DAG1,RTN4RL1,PTPRJ,IDE,ATP1A1,PAFAH1B3,MMP17,PSMD3,ADAMTS14,CHMP4B,ANXA9,RPL22,LTA4H,ST3GAL1,CMTM4,CTDSP1,MAN2B2,COL9A3,PACSIN2,ADGRG1,CD63,TAB3,RUSC2,CTSB,BLVRB,GNAL,CDCA8,GDF15,CRABP2,VPS26A,DNAJB9,SIRPA,CD109,FAM63A,ALDH7A1,ATP2B1,GCNT1,FAH,P2RX4,FBLN5,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,COL7A1,CAPNS1,GGH,FXR2,RNPEP,SCRN2,PRDX4,DDX23,FUCA1,DDAH1,SERPINA1,FAT4,TWSG1,SCG2,FGF18,TMC5,PGRMC1,PKD2,SH3BGRL2,ACADM,ICOSLG,TBC1D4,SAT2,LAMP1,GAA,TXN,HSPG2,ATP8A1,FAM129B,PPFIBP2,PSME1,NANS,PLXNA1,VASH1,NCS1,CTGF,AOX1,SERINC2,TACSTD2,MTMR11,TFG,ZBTB18,LAMP2,LOC81691,SNTB2,HSPA12A,MGAM,GALNT7,AURKB,SLC25A5,TP53I3,RAB2B,KDSR,AREG,PTER,PPP2R4,BMP1,SERPINI1,RTN3,HLA-E,KIF23,NDUFA4,SLC1A3,CALR,DOPEY2,ITGA3,CYR61,SNX18,LYPD3,VASN,RPL39,SORL1,CYSRT1,CD70,OSTF1,CTSD,RIMS2,GFPT1,QSOX1,KLK5,MFI2,PRSS23,CALM1,ANO6,PIP4K2C,PYGL,NPC2,CYFIP2,PKM,JADE2,ANTXR1,STX3,FRMD4B,FAS,PRKAG2,MATN2,APPL2,KLK7,EFNA1,EHD1,SLC2A4,S100A11,TRIP10,ST14,NDRG1,IQGAP1,BROX,FTH1,KCTD12,CD274,AIFM2,DDR1,TMPRSS4,GNB2,EPS8L2,CD46,APLP2,NOV,RALB,DAB2IP,EPHB4,LGMN,TSPAN1,FLOT2,SULT2B1,NAGA,TMBIM1,GPX4,SEMA3B,MYO5B,LYRM1,CLSTN1,UTRN,ATP1B1,AKR1E2,H2AFV,ALCAM,SP4,ZMPSTE24,CMTM7,EPHA10,ACYP1,STK26,PPP1CB,RAB29,NRG1,B4GALT3,MAMDC2,WASF3,PLSCR4,PCOLCE,IGFBP6,HAPLN3,EPS8,GPR180,SEPP1,SPR,EFNB1,LGALS3BP,HLA-A,COX7A2,WWP2,MGAT1,FUT8,FJX1,CD9,SLC44A2,TAGLN2,ERBB3,PDGFC,B3GNT2,SHMT1,CASK,ALDH2,FURIN,PARP4,C1GALT1C1,UBAC1,YES1,AIF1L,GPLD1,CRTC2,NUCB1,TIMP3,CTNS,ACADSB,PRDX3,ABCB1,ERAP1,SERPINB5,ARSB,RGMA,LTBP1,ST13,CRYM,HEBP1,MPP5,TAF6L,ERP29,ECI1,EPCAM,RAB15,METTL7A,TSPAN6,DPYSL2,DLG1,CAPG,AKR1B1,RP2,MYH14,CTTN,NLRP4,OLFML2A,SOD1,ASXL1,LAP3,ITCH,ARHGDIB,TCN2,SEC14L2,ZNF114,GPRC5B,UEVLD,TRIM45,CAB39,GLA,CPPED1,CAPN1,PCSK5,GRN,FAM213B,LASP1,SERPINE2,ASL,CALM3,PM20D2,ADAMTSL4,QSOX2,SPP1,CES2,CA2,PFKL,FAM20C,OCRL,COL6A1,PRKCI,HLA-C,SLC12A2,SNED1,VWA1,NUBP1,C3orf58,EGFR,MUM1L1,GNAS,INSR,PLPP3,SH3BP4,CTSA,PITPNA,EGFL7,KIF12,SHROOM2,COL16A1,PROM2,ZSWIM5,IL15,PSME2,HDAC11,SOD2,COL18A1,MRAS,EXT2,ARTN,SMO,GOT1,ECE1,PDIA6,LOXL1,HSPA2,CHP1,GCA,IGSF8,GLO1,ERBB2IP,CD40,BHLHB9,SECTM1,CANT1,SPTBN5,LIFR,ANXA3,ENO2,TSPAN15,SERPINB9,COL4A5,ITGA2B,TMEM63A,IRF2BPL,MLPH,TAF1B,A4GALT,BMP7,GALNS,ACTA2,H2AFY,HSPA13,MYO5A,SYPL1,PGM1,RAB3B,WNT10B,NDRG3,ENDOD1,CTSL,HLA-B,GAREM2,RND3,DHRS2,PRCP,CTSV,RAP2C,UBE2D2,UACA,GLB1,ATP6V1C1,PLOD3,LRRC57,CD33 |
| 2.591e-06 | -12.86 | Signaling by FGFR1 | REACTOME pathways | R-HSA-5654736 | 314 | 78 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,CBL,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.616e-06 | -12.85 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | 280 | 70 | 17758 | 2588 |
SLC25A24,PAPSS2,GNPDA1,XYLT1,IL27RA,PLAC1,EGR3,SYTL4,CCNB1,EMP2,ZNF385B,APLP2,TSPAN6,ATRNL1,TECR,MYBL1,TIPARP,CPE,DVL2,CYP1B1,SUSD3,LAMP2,CELSR2,TNIP1,TFAP2C,F12,SAV1,TP53I3,IRX3,IRS2,TMEM164,KCNMB4,PPP2R5A,PDLIM3,P4HA2,LRIG1,DHTKD1,SLC27A3,MRC2,RBM24,CALB2,HMGN3,COL4A5,COX6C,IL17RB,ADD3,ADORA1,SLC27A6,IGF1R,ADCK2,SGK3,RFX5,C12orf75,KIF20A,PRSS23,AMFR,SYBU,PIK3R1,PARP4,STMN3,AK4,EMP3,PLIN5,CYB5A,SERTAD2,TRIM69,RAP2C,RAB31,RPS6KA3,JARID2 |
| 2.622e-06 | -12.85 | ODONNELL_TFRC_TARGETS_DN | MSigDB lists | ODONNELL_TFRC_TARGETS_DN | 127 | 39 | 17758 | 2588 |
ARHGAP11A,SPC25,DEPDC1,DLGAP5,FOXM1,NDC80,ERCC6L,CCNB1,TOP2A,CCNA2,NPNT,KIF14,RANBP1,PRC1,PLK4,CKS1B,BUB1,PLK1,HMMR,PCGF5,TAF5,CENPA,KIF20A,ASPM,CDC20,MYBL2,WHSC1,CKAP2L,KBTBD8,AURKB,ANLN,KIF11,CDK1,DCP2,ZNF628,FAM83D,AURKA,CENPE,ZBTB6 |
| 2.673e-06 | -12.83 | ZWANG_EGF_INTERVAL_DN | MSigDB lists | ZWANG_EGF_INTERVAL_DN | 194 | 53 | 17758 | 2588 |
KLK10,ARMC7,FBXO2,TESK2,JAG2,CCNL1,EMP2,SPSB1,ELF3,IRF2BPL,CA2,LLGL2,ARHGEF37,ZFP36,KLF3,DAPK1,FAM63A,KCNS3,DUSP10,DAB2IP,MXD3,IFIT1,KLF9,OSBPL7,FAM134C,HES1,MBP,CXXC5,CITED4,ADCK3,BCL9,PIK3R1,PLEKHA7,SPATA13,GYLTL1B,TFAP2C,RHOB,GIGYF1,IRX3,BCAR3,ARHGAP24,BTG1,TIMP3,RPL12,KIAA0141,MADD,MATN2,AGFG2,PLD1,UNC5B,OSR1,REEP4,IRF1 |
| 2.673e-06 | -12.83 | GSE17721_LPS_VS_POLYIC_1H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_1H_BMDM_UP | 194 | 53 | 17758 | 2588 |
KLF2,ACACB,ARHGEF3,FRMD6,PKP2,CCNL1,BCL2L1,LACTB2,GALM,NUCB2,CARD10,ICAM1,DNAJB9,CYP1A1,TIMP1,PPP1R10,CYR61,TACC2,ZFP36,ARL1,ALDH7A1,SELK,TIPARP,SIRT1,FADS2,TGIF1,MARK1,PLSCR1,KIF20A,LAP3,PARD3B,PCBP3,LPGAT1,SPATA13,PTGER4,KDELR3,PIM3,FOS,TCEAL8,TCN2,CDK5R1,BCL10,SERTAD2,ETS2,RCBTB2,ACYP1,AREG,RND3,CSF1,SH3GLB2,GLB1,MAFF,USP16 |
| 2.673e-06 | -12.83 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP | 194 | 53 | 17758 | 2588 |
LAMP1,NDRG1,FRMD6,CAMKK1,ITGA6,MCOLN3,SELL,P2RX7,KCTD12,BCL2L1,PHLPP1,SYTL2,ICAM1,RCN1,ADORA1,ITGB8,PIK3AP1,SNX18,CASC4,SLC16A6,PRKCI,CKS1B,TNFRSF18,RAB20,NTN4,CACNA1D,NCEH1,SULT2B1,MGAT5,NEB,EPHX1,ADAM17,NPC2,ATP1B1,CBL,SESN1,CD83,MAGED2,PI4K2B,SWAP70,ETS2,AXL,FAM3C,INPP4B,NETO2,TLE1,SAMD8,KLF11,LEMD1,KIF12,LTA4H,CD81,RRAGD |
| 2.675e-06 | -12.83 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | 234 | 61 | 17758 | 2588 |
GCLM,NQO1,IL15,DNAJB2,INPP5D,BLVRB,GDF15,PLA2G16,DHRS3,MAP1LC3B,TNFSF9,LMNA,MXD1,EPCAM,ZYX,SPP1,PSMD1,ZFP36,PHTF1,KIAA0319,TNPO2,ACTA2,PHKG2,CAMK2G,PSMA5,CTH,TUBA4A,LAMP3,DUSP1,UFD1L,LGALS8,MICB,SAT1,KCTD20,DUSP4,MEST,FOS,DGKE,MAP1B,FAS,STK17A,GABARAPL1,PGF,NUCB1,IDE,CASP7,PDLIM3,MAP2,PLK2,ITGA7,P4HA2,WWTR1,LRIG1,GLA,GEM,TMEM159,F2RL1,HSPB1,MAFF,COL16A1,ABCG1 |
| 2.688e-06 | -12.83 | positive regulation of catabolic process | biological process | GO:0009896 | 367 | 88 | 16441 | 2455 |
DLGAP5,CNOT8,PNPLA2,PSME2,CUL4B,CUL1,P2RX7,PSME1,CCNB1,SNX9,BARD1,APC2,BCAP31,EPM2A,IER3,PSMD1,RALB,DACT1,ZFP36,PSMC2,CDKN1B,DAB2IP,TWIST1,OSBPL7,TIPARP,PLK1,SIRT1,VPS11,TRIM8,AKT1,ITCH,CDC20,EZR,RNF19B,CDK1,VCP,IRS2,PLK2,PSMD3,NKD1,PSMC1,ARNT,PRKAA2,TNRC6C,PINK1,SCOC,GGA1,DNAJB2,SH3D19,SOX9,PRKAA1,ASB9,PSMD7,PSMD10,TRIB2,PPP2R3A,RB1,RNF128,CTSC,PTEN,GPC3,BAX,PLEKHF1,TRIM21,SORL1,MYLIP,PHKG2,PSMA5,SOCS5,PSMB4,GCLC,NUB1,FURIN,PIP4K2C,PPARA,PRICKLE1,TP53INP2,PSMA4,PLIN5,GPLD1,INSR,SH3BP4,AURKA,CD81,NDFIP1,UBE2C,TOB1,ESPL1 |
| 2.696e-06 | -12.82 | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | MSigDB lists | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | 87 | 30 | 17758 | 2588 |
CD99,HES1,TRIM2,HLA-E,CRIP2,ADO,AK4,RUNX3,RNF113A,FOS,ZDHHC3,STEAP1,SIRPA,GABARAPL1,GLCE,CDK14,MAN2A2,CCND1,KDSR,ATP1A1,UAP1,JAK1,DPYSL2,STAT6,DAPK1,NPTXR,CITED2,STARD13,RAP1GAP,IL1RAP |
| 2.716e-06 | -12.82 | Insulin Signaling | WikiPathways | WP481 | 163 | 50 | 4455 | 729 |
PRKAA2,SLC2A4,SORBS1,INPPL1,RPS6KA1,PRKAA1,FLOT1,MAPK4,KIF5B,RAC2,RPS6KA2,IGF1R,PTEN,SHC3,PFKL,SGK3,MAP3K9,PRKCI,PIK3CA,SGK1,GYS1,MAPK11,PIK3CD,MAP3K7,MAPK7,FLOT2,MAP3K3,AKT1,PIK3R1,PRKCQ,CBL,ELK1,FOS,MAP3K6,RHEB,SOCS3,IRS2,PTPRF,ENPP1,TSC1,INSR,MAP3K11,MAPK13,ARF6,MAP3K5,TBC1D4,GAB1,RPS6KA3,MAPK12,EHD1 |
| 2.716e-06 | -12.82 | GOLGI_APPARATUS | MSigDB lists | GOLGI_APPARATUS | 224 | 59 | 17758 | 2588 |
GOLIM4,IL15,GGA1,BACE1,TGOLN2,RAB6A,DSE,EXT2,CHST2,SLC9A7,PICK1,DOPEY2,ENTPD4,FUT2,LMAN2L,ARL1,NECAB3,OCRL,SLC35B4,STEAP2,FUT1,LMAN1,F2R,ITM2C,SLC35A1,RPGR,MPHOSPH9,SCYL3,CCDC88A,B3GALT6,QSOX1,CLCN3,KIF20A,TMEM43,COG2,ACO1,FURIN,KIF1C,PKMYT1,OPTN,GLCE,GNAS,TAPBP,LDLRAP1,STX10,DNM1L,HTT,ATP7B,SECTM1,ARAP1,FGD6,GLA,PLD1,PLIN3,F2RL1,ABCG1,GOLGB1,PCSK5,FGD1 |
| 2.747e-06 | -12.80 | regulation of cell growth | biological process | GO:0001558 | 383 | 91 | 16441 | 2455 |
GAS2L1,TNK1,NF2,FOXM1,RPS6KA1,TP53,ERBB2,PLXNA1,KIF26A,CDKN2C,NOV,CTGF,CDKL5,KIF14,DPYSL2,BCL6,DNM2,CDKN1B,SEMA3G,CTTN,ACSL4,CDKN2D,EBAG9,SEMA3B,SIRT1,SMARCA2,CDKN2AIP,PSRC1,ING1,AKT1,ITCH,SERTAD3,CDA,CLSTN1,PRKCQ,EAF2,ULK2,JADE1,ENPP1,PTPRJ,LIMK1,ADIPOR1,EFNA5,NRG1,PLXND1,CHPT1,SEMA6B,TAOK2,IGFBP6,SERPINE2,ARHGEF11,PSMD10,TGFBR1,CRABP2,HDGFRP2,IL17RB,SPP1,CXCL16,CYR61,MEGF8,SGK3,SGK1,H2AFY,ADAM15,IGFBP2,TNFRSF12A,NTN1,WNT3A,OSGIN1,RIMS2,ADAM17,RHOA,FBLN5,MFI2,KIAA1109,ILK,BCAR1,NDRG3,CDK5R1,MAP1B,RASGRP2,BTG1,SERTAD2,SEMA4D,ACVRL1,CGREF1,SH3BP4,FHL1,SEMA3A,L1CAM,RPS6KA3 |
| 2.776e-06 | -12.79 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | MSigDB lists | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | 29 | 15 | 17758 | 2588 |
CALM2,PLCG1,FYN,PIK3AP1,STIM1,PLCG2,CALM1,PIK3R1,CALM3,PIK3CD,ITPR2,CBL,ITPR3,SYK,SH3KBP1 |
| 2.785e-06 | -12.79 | Wnt signaling pathway | biological process | GO:0016055 | 244 | 64 | 16441 | 2455 |
LGR4,XIAP,GATA3,NDRG2,GRK6,SDC1,APC2,KREMEN1,CDK14,CCND1,CTNNB1,DACT1,MITF,PLCG2,SMO,TAX1BP3,CDH3,DIXDC1,CPE,DVL2,MARK1,KREMEN2,CELSR2,PTPRU,FZD4,PYGO1,ROR1,FZD7,CXXC4,PTK7,NKD1,TRABD2A,TLE1,CTNND1,PRKAA2,CTHRC1,LRRFIP2,PRKAA1,LRP4,AES,ZNRF3,NOTUM,HMGXB4,PPP2R3A,FZD6,MESDC2,CTNNBIP1,PTEN,BRD7,WNT3A,ZRANB1,AMOTL2,WNT10B,BCL9,AMER1,TCF7,NPHP3,CSNK1G1,PLPP3,RYK,FZD5,RARG,ZBTB33,RNF146 |
| 2.791e-06 | -12.79 | single-organism catabolic process | biological process | GO:0044712 | 1004 | 202 | 16441 | 2455 |
GAA,FAF2,AASS,CRYM,CPT2,PNPLA2,HEXB,MCCC1,LMCD1,FBXO2,TRAPPC8,PLA2G16,OAT,HDAC6,MAP1LC3B,ECI1,CALM2,INPP5E,PHYHIP,TYMP,CYP1A1,ENTPD4,PSMC2,DDHD2,PIK3CA,FUT1,PPP1CA,ACOX2,APOBEC3G,CYP1B1,PLK1,SPATA18,CDA,CCBL2,SLC35C1,KLK6,PNKD,MYOM1,CYP4F3,POR,VCP,COL12A1,PLCH1,ENPP1,PLCG1,NEIL1,HPSE,WIPI1,MYLK,DHTKD1,GLA,PSMC1,PPP2R5D,NR2C2,MRC2,ALDH6A1,DHPS,DNAJB2,ASL,CALM3,SLC1A3,ATG4A,GNS,ZCCHC17,PFKL,RIMS3,FBXO7,FAM13B,BDH1,COL6A1,PCYOX1,PRKG1,AHCY,ALPK1,STT3B,ACAD8,CTSD,NCEH1,PLCB2,GAD1,PHKG2,MCCC2,CYP26B1,UFD1L,PRODH,CALM1,PDE5A,PYGL,PKM,AMDHD1,PDE11A,MMP15,DHDH,NUDT16,NT5C2,FAAH,COL13A1,MDH1,YOD1,PLD1,COL16A1,XDH,PLA2G4A,P2RX7,COL18A1,LPIN3,PRKACA,NUDT12,CYP39A1,CYP26A1,EPM2A,CYP4F11,PLCG2,FABP6,GOT1,PDE4D,PHKA2,ETHE1,NAGA,GM2A,ATG4D,CHP1,CTH,ENPP4,SEC61B,COL6A2,ERLEC1,PFKFB2,ATP1B1,AKR1E2,GABARAPL1,DNAJC10,DUOX1,ALDH3B1,ALDH5A1,PAFAH1B3,ACAD10,ABHD12,WFS1,PEX2,PNPLA6,ADAMTS14,PPP1CB,COL9A3,GALK1,PINK1,HSP90B1,ENO2,GCAT,CIT,CTSB,JKAMP,HAL,BLVRB,COL4A5,PLD2,APOBEC3H,FBXO6,PNPLA5,DNAJB9,SGPL1,FUT2,ADORA1,OXCT1,PTEN,GALNS,FUT8,UBE2J1,ECI2,ADAM15,ALDH7A1,HMGCL,ABCD1,FAH,HMMR,ACBD5,PGM1,PCCB,ADAMTS2,ADAM17,SHMT1,ALDH2,GUSB,AMFR,FURIN,OGDHL,COL7A1,BLVRA,FUCA1,CTSL,DDAH1,ACADSB,PLOD2,PRDX3,SLC35B3,PLA2G15,PGM2L1,GLB1,ACADM,ARSB,WDR45B,ACOT7 |
| 2.807e-06 | -12.78 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | 349 | 83 | 17758 | 2588 |
LFNG,ATP2C2,CACNA2D2,LMCD1,GATA3,EMP2,FAM46C,CCND1,ZFYVE16,CYHR1,KCTD15,RABEP2,IQCE,PPP1R16A,DLG3,SCYL3,CERS2,MYO5B,CAMSAP3,CXXC5,KIFC2,TNIP1,FZD4,KIAA0040,NKAIN1,ARHGEF26,ENPP1,DHRS13,ABHD12,WFS1,ZNF704,SH3GLB2,CANT1,ANXA9,TTC9,POMT1,TC2N,KLF2,ANKRD13D,FRMD4A,GGA1,TSPAN15,CYB561,NUCB2,RSAD1,RND1,DOPEY2,MLPH,LLGL2,SLC16A6,MGAT4A,TRIM3,ATP8B1,TMBIM6,TSPAN13,CACNA1D,ERBB3,SLC35A1,MCCC2,SNED1,ZNF84,SLC37A1,TESK1,HMG20B,GOLT1A,SPTLC2,NPDC1,RHPN1,RHOB,SOX13,MAGED2,PTPRF,EPN3,TJP3,PVRL2,TADA2B,ARRB1,KIF12,ZMIZ1,TOB1,RUSC1,FOXA1,ABCG1 |
| 2.808e-06 | -12.78 | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | 265 | 67 | 17758 | 2588 |
EXPH5,TXN,FOXM1,PTTG1,NDC80,KIF2C,BARD1,PHLDA1,CENPN,FANCI,TUBG1,MANF,RNASEH2A,PDIA6,ETV4,CKS2,PLK1,CENPA,AKT1,NUSAP1,DUSP4,CCNF,H2AFV,CDK1,ARF4,DNAJC10,FASTKD1,DNM1L,XRCC3,HSP90B1,DEPDC1,SERPINE2,HJURP,ARL4C,CDCA3,RACGAP1,CKAP5,IRAK1,ITGA3,RANBP1,PRC1,CKS1B,USP1,TNFRSF12A,NUP85,SPRY2,MSH6,SMC4,GFPT1,ZWINT,ELK3,ASPM,PLAUR,WHSC1,STK17A,BCAR3,UAP1,PRDX3,RND3,FAM3C,AURKA,STK39,PLOD3,NUP37,NCAPG2,MELK,EHD1 |
| 2.827e-06 | -12.78 | DORN_ADENOVIRUS_INFECTION_24HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_24HR_DN | 43 | 19 | 17758 | 2588 |
NR4A1,FHL2,COL7A1,EGR3,SRSF5,CD83,IER3,BCAR3,CCND1,TOP2A,H1F0,RND3,CYR61,PLK2,NFKBIA,SGK1,TNFRSF12A,EFNA1,NFKB2 |
| 2.872e-06 | -12.76 | stomach-adenocarcinoma | COSMIC cancer mutations | stomach-adenocarcinoma | 4272 | 714 | 17775 | 2585 |
ACACB,ADD1,FAM160B1,IBTK,GRIK2,AASS,SLC25A13,SMARCAL1,CACNA2D2,MMADHC,TRAPPC8,LYNX1,DPP8,BARD1,PHF1,LTBP3,EPDR1,TP73,WEE1,PSMD1,TGFBR3,MUC4,DNAH6,ALDH1A3,KLF3,ATP13A3,PPP1CA,PIK3CD,RNF26,TIAM1,TIPARP,ANKRD9,MGAT5,ODF2L,SPEF2,TMEM151A,PRKAR2B,COL12A1,LCP1,SLC44A3,ENPP1,PLCG1,TRIM47,MPRIP,WDR11,DNM1L,ATP7B,MYLK,FAM114A1,RNASEL,ITPKA,GAB1,E2F8,NFKBIE,FAM169A,GGA1,SLC36A4,GPSM2,HPCAL4,ATG4A,FLII,ZCCHC17,WDFY1,FRY,FAM13B,RANBP1,PCYOX1,MAP3K9,USP1,ALPK1,STT3B,CNGA1,ZMYM1,MYLIP,KIF20A,SALL4,STAT4,PLS1,KIF20B,NPHP3,SPTLC2,DPYSL4,PTPRF,IL1R1,CACHD1,NCOA3,SLC4A4,HTT,SETD3,CLMN,OSMR,DYSF,ALG2,NDE1,SERPINB1,RPS6KA3,XDH,MTM1,RHBDL3,WDTC1,RGS20,PKP2,NUF2,GRK6,MGST2,MOCS1,APPBP2,UHRF1BP1L,RBM23,ST5,SCNN1A,CDH1,DACT1,XYLT2,RTKN2,ACSL4,MYT1,SCN3A,MX1,ERMP1,PFKFB2,NRBF2,FZD4,AGPS,PTPN9,SYNE2,SAT1,HTATIP2,TRIM7,EBF2,PEX5,SHROOM3,CDK19,AXL,SIPA1L1,PNPLA6,PDXK,RGS14,ARNT,HSP90B1,FAM189A2,CKAP2,GCAT,MAN1A2,BACE1,OSGIN2,GMCL1,ANO9,PKN1,KCNC4,SLC25A43,BEX2,HOXB2,NEO1,ZFX,ADD3,ITGB8,SLC27A6,KCNK5,GPC3,CALD1,MGAT4A,TMEM62,TUBGCP6,FDXR,FAM102A,IGFBP2,AK3,SGCB,CASD1,HCN3,POU6F1,RAPGEF2,MRS2,CXorf57,RAB3IP,BLVRA,SKA1,CNTNAP1,PLOD2,ACVRL1,NR1D2,DBI,ARFGAP3,CENPE,ITGAV,USF2,SHOX2,DCBLD1,ACOT7,TLL2,UNKL,ILDR1,BCAM,KIAA1462,AGRN,GNPDA1,CNOT8,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,TEX2,MGAT5B,ITPR2,HDAC6,SDC1,SPTB,NUP210,TM9SF2,CTNNB1,NPNT,IL6ST,SLC44A1,MITF,ANO4,TLN2,DDX59,CCDC38,ZNF462,PLK1,MCTP1,MARK1,CD55,CELSR2,HN1L,STAU2,CBX6,C12orf65,ANLN,IDH1,SESN1,CLCN2,LHFPL2,RHEB,VCP,TRIM9,PLEKHG6,MFAP3L,HS6ST1,PLCH1,TBC1D17,MAP2,RAB11FIP1,KLF11,KPNA2,EPB41L4A,POMT1,PRKAA2,RUNX2,ZCCHC24,RASA2,SORBS3,CNTNAP2,IL18R1,MYO5C,TNS3,IGF1R,RINL,ICAM5,FCHO1,SLC30A6,MPHOSPH9,ABCC1,CYP26B1,DPYSL5,CHSY3,WDR72,TESK1,CORO2A,MGAT4B,SCRIB,EIF2AK1,BCL2L13,UNC45B,PRX,C18orf8,PHLPP2,CSF1,MFSD2A,SEMA3A,CDAN1,UPF3B,TMX4,DGKA,TP53,ERBB2,SLC7A2,CYP26A1,SYTL2,PER2,CDK14,PDGFA,TTC21B,SRPX,WDR44,TACC2,CDH3,GLB1L2,ESPN,NOTCH3,LMAN1,SCN2A,GM2A,CTH,CPD,SIRT1,ERLEC1,AKT1,DUOX1,IDE,PTPRJ,RBL1,PTK7,STK38,PSMD3,EFNA5,RPL22,BTBD6,NDST3,ZC3HC1,MAN2B2,PINK1,PACSIN2,GOLIM4,TRAPPC10,GNAL,GNE,BLVRB,ERCC6L,CDCA8,HMGN3,GDF15,VPS26A,PPP2R3A,NRP2,DNAJB9,SH2D4A,ZDHHC21,CD109,FOXP2,CEP97,UBE2J1,SLC35B4,BUB1,TLE6,ATP2B1,DLGAP1,HMMR,MOSPD2,PSMB4,PRICKLE1,GGH,COL7A1,TXNDC11,BBS2,BCAR1,BANK1,FAT4,E2F1,CLIP4,FAM117A,TBC1D4,HIPK3,ARHGEF9,ARHGEF4,GOLGB1,DIS3L,SUN1,PNISR,PPP4R4,TTC39B,LGR4,TSC22D3,ATP8A1,CUL1,SLC20A1,PICK1,CHST2,NCS1,PAK6,CTGF,ELMO2,IL31RA,PIK3CA,KCNS3,STEAP2,AOX1,ATRNL1,SNX16,HYLS1,METAP2,LOC81691,SPATA18,PBK,TNS1,AURKB,SLC17A5,RAB2B,ULK2,SGPP1,SFXN1,KDSR,PLK2,GNPTAB,SH2D3C,TBX1,NKD1,LRIG1,PRDM5,UNC5B,TRAF5,RTN3,LZTS1,DLAT,DDX58,RECQL,MRC2,FRMD4A,KIF23,AKAP17A,C6orf106,TXNDC9,ISYNA1,APBA1,SH3RF2,MESDC2,MECOM,DOPEY2,PIK3AP1,SNX18,NECAB3,VASN,MSH2,RUNDC3B,DAPK1,SORL1,CACNA1D,C8orf58,PIKFYVE,SYTL3,KCTD3,RIMS2,TRAK2,IGSF3,EPB41L5,PIGC,QSOX1,FADS2,GCC2,KIAA1841,ZNF84,MMD,TBC1D8B,CALM1,AMER1,ANO6,PYGL,ANTXR1,DGKH,PLEKHH2,SLC4A3,APPL2,SFMBT1,PCDH19,NR4A2,CDK18,CABIN1,MAP3K5,IFIH1,NRBP1,PKD1L2,SPRED1,TCTN2,CAPN12,CEP70,TRIP10,NLRX1,BROX,IQGAP1,FTH1,TMEM19,DDR1,MNS1,CYP39A1,ZFYVE9,APLP2,RALB,EPHB4,NR2C1,MYO5B,SEC23A,COG2,CAPN6,PANK1,TEP1,UTRN,CLSTN1,SLC11A2,C15orf39,CBL,AKR1E2,ITPR3,ALCAM,ATP10D,NIN,OSBPL2,EPHA10,PPP2R5A,JAK1,ACAD10,TSPAN18,KIAA1804,NRG1,HS3ST3B1,MLKL,B4GALT3,COBL,NUDT6,PCOLCE,PLSCR4,HAPLN3,CDCA3,CBLL1,HERC5,NES,PLD2,DNAH3,PNPLA5,SIX4,CKAP5,WWP2,E2F7,PHF7,OXCT1,PTEN,FUT8,SGK3,PRC1,ATP8B1,SLC44A2,TAGLN2,ERBB3,MAP3K7,MSH6,SMC4,PCCB,RASGRF1,TGIF1,ALDH2,ARAP2,PAPD7,ZC3H11A,VAMP3,PARP4,DIAPH2,CRTC2,CDK5RAP1,CTNS,RCBTB2,TBX18,SLC25A40,ABCB1,ERAP1,ETAA1,WDR91,WDR62,SLC25A38,NCAPG2,ARSB,ESPL1,OCLN,DEF6,USP16,JARID2,EXPH5,LTBP1,CASP3,TMEM184B,CPT2,EPHX4,DNER,KREMEN1,TMC1,ABCD4,SIPA1L2,LRRC6,CDKL5,DPYSL2,ANKFN1,PHTF1,DLG1,ANKRD12,AKR1B1,ASH2L,SLC39A10,IL1RAP,STK35,CXXC5,ITCH,SEC14L2,EDNRA,HPSE,FASTKD1,MADD,IARS2,CHPT1,PSMC1,CPPED1,NR2C2,STARD3NL,CD99,GRN,PYROXD2,SAMD9,QSOX2,DUSP5,TYW3,CA2,CES2,PRKCI,LIMCH1,RFX5,HLA-C,SLC12A2,ALS2CL,CCDC88A,HP1BP3,PARD3B,BTN3A2,PDE5A,KIAA1109,NUBP1,MFSD7,RANBP9,GNAS,FECH,TSC1,ONECUT1,UAP1,KIF12,JAK3,COL16A1,SNX30,KLF7,FBXW5,LMO7,LZTFL1,SLC25A24,ZSWIM5,SPC25,COL18A1,MICALL2,MXD1,SLC25A48,SS18,KHNYN,KIF14,FRYL,EPB41L4B,APIP,SCYL3,SUSD3,SOAT1,MAP3K3,BAG4,ERBB2IP,TMTC2,PDHX,STAT6,RCAN2,SGOL1,SORT1,ARHGEF11,ARHGEF7,SHPRH,POC1B,FRMD6,LRP4,TGFBR1,COL4A5,NOTUM,INTS8,SBF1,FAM167A,XPR1,IL17RB,MZT2A,LLGL2,RRBP1,KIAA0319,ACTA2,H2AFY,ARVCF,IQGAP3,MYO5A,SUN2,SYPL1,ADAM17,GCLC,ASPM,RC3H2,MBNL3,NDRG3,SPAG1,KLHL2,C2orf70,DHRS2,CSGALNACT1,PLOD3,L1CAM,LRRC57,NGEF |
| 2.874e-06 | -12.76 | STEIN_ESRRA_TARGETS | MSigDB lists | STEIN_ESRRA_TARGETS | 502 | 111 | 17758 | 2588 |
GAS2L1,ACACB,TRIM2,TMEM184B,CEP70,UGP2,EPAS1,GNPDA1,VANGL1,RPS6KA1,TMX4,APOO,SOD2,NDRG2,PRSS22,TEX2,NANS,ISOC2,MGST2,ECI1,IER3,BTG3,CYP1A1,METTL7A,TACC2,MITF,TRPC1,STEAP3,GOT1,NFU1,MANF,EGLN3,PXMP4,SULT2B1,GM2A,CYP1B1,PPIF,TRIM8,KIAA0040,SLC39A8,CASP9,HTATIP2,PRKAR2B,ARFRP1,ATP1B1,PDHX,SEC14L2,GABARAPL1,TRAM2,FASTKD1,SLC25A4,ACYP1,WIPI1,ZNF165,RAP1GAP,LIFR,PPP2R2D,DLAT,FAM134B,HLA-E,PDCL,GMCL1,GDF15,IFT27,SCML1,PDCD10,CA2,CTSC,KCNN4,NECAB3,BMP7,FDXR,OPN3,FAM63A,ECI2,KANK2,ALDH3A2,MSH6,DUSP1,TRAK2,GFPT1,NAGPA,OPLAH,PGM1,TACC1,UBAC1,PLS1,PCTP,SPTLC2,C4orf27,MAP1B,CD83,EPN3,NUCB1,FA2H,ETS2,TJP3,ACADSB,TIMM8A,SLC25A40,PRPS2,SLC2A6,OTUB2,AURKA,MDH1,ACADM,PLIN3,TRPC3,HOOK1,OCLN,EGLN1 |
| 2.880e-06 | -12.76 | Ras protein signal transduction | biological process | GO:0007265 | 394 | 93 | 16441 | 2455 |
SPRED1,PSME2,TP53,ERBB2,NRG2,RASGRP3,MRAS,PSME1,PDGFB,SPTB,EPS8L2,PDGFA,CALM2,PAK6,RAB15,CCNA2,PSMD1,SHC3,RALB,PSMC2,BCL6,TAX1BP3,DAB2IP,RAB20,RASGEF1A,RAB27B,TIAM1,RASGRP1,FRS3,ARHGDIB,RAB38,RAB2B,IRS2,FYN,JAK1,LIMK1,PLK2,PSMD3,MAPK13,SPTBN5,NRG1,RAB29,ARHGAP4,PSMC1,MAPK12,ARHGEF3,ARHGEF11,ADGRG1,RASA2,EPS8,PSMD7,RAB23,PSMD10,CALM3,NCKAP1,RAB6A,IFT27,FGF19,DUSP5,RB1,MCF2L,PAK2,MAPK11,ERBB3,IQGAP3,NTN1,NCAM1,PSMA5,CAMK2G,FARP2,RASGRF1,RAB3B,RHOA,PSMB4,CTNNAL1,MAPKAPK3,RAPGEF2,CALM1,GRIN1,STRADB,PSMA4,RHOB,EGFR,RASA1,RASGRP2,MAPKAPK2,FGFR2,FGF18,RAP2C,RAB31,GRIN2D,PLD1,JAK3 |
| 2.908e-06 | -12.75 | GNF2_SMC4L1 | MSigDB lists | GNF2_SMC4L1 | 83 | 29 | 17758 | 2588 |
HMMR,PCCB,ZWINT,DLGAP5,FOXM1,CKAP2,ASPM,CDC20,NDC80,CDCA8,RACGAP1,NUSAP1,KIF11,CDK1,FANCI,PRIM1,TOP2A,PCNA,CCNA2,PRC1,PLK4,MSH2,AURKA,USP1,CCNB2,E2F8,SMC4,METAP2,CKS2 |
| 3.000e-06 | -12.72 | MODULE_33 | MSigDB lists | MODULE_33 | 371 | 87 | 17758 | 2588 |
MYL9,LTBP1,UGT8,NF2,HSPG2,HOXB7,EPAS1,CRYM,THRA,EPHA4,SOD2,ERBB2,MAPK4,TP53I11,SLC20A1,SCNN1A,RPS6KA2,RGS3,CAPG,BCL6,IFIT1,LGMN,NEB,CPD,MX1,KIAA0040,CR2,KLK6,DUSP4,TCN2,NFIX,MAN2A2,PAFAH1B3,PTK7,SECTM1,TLE1,MAOA,NRG1,APBA2,MAPK12,PRSS8,PCOLCE,NKX3-1,IGFBP6,ITGA6,DCAF7,BIK,HAL,SERPINB9,SELL,ASAH1,GDF15,TRIB2,SEPP1,MERTK,ETS1,TSPAN7,LGALS3BP,ELF3,RAC2,ANK1,GATA2,RIMS3,CALD1,COL6A1,CD9,ACTA2,CD70,MAPK11,MAPK7,GCNT1,SHMT1,MMD,TESK1,PTPRH,FURIN,MEST,SPTLC2,IL1R1,CNTNAP1,KIAA0141,FAAH,PLOD2,NAB2,DRP2,JAK3,CSRP2 |
| 3.009e-06 | -12.71 | embryo development ending in birth or egg hatching | biological process | GO:0009792 | 601 | 131 | 16441 | 2455 |
EMX1,ACVR1,ADD1,HSPG2,EPAS1,GATA3,PLAC1,CCNB1,PDGFB,CYP1A1,CTNNB1,DLG1,ARNT2,ZBTB18,SPEF2,TFAP2C,ICMT,ZFAND5,GINS4,EDNRA,HS6ST1,PLCG1,TBX1,HOXA9,TRAF3IP1,TANC2,APBA2,GAB1,E2F8,MAFF,PCSK5,GRN,KLF2,RUNX2,CDKN1C,RAB23,NCKAP1,APBA1,ELF3,MECOM,BMP2,VASP,CYR61,GATA2,MEGF8,OCRL,MSH2,NEK2,WNT3A,TMED2,MDFI,EPB41L5,SALL4,DCHS1,VEZT,SCRIB,KIF20B,EGFR,G2E3,GNAS,TSC1,NCOA3,HTT,CCNB2,RARG,EGLN1,HOXB7,GRHL2,LFNG,ST14,TP53,WDTC1,BCL2L1,OSR2,STIL,PRKACA,RCN1,LMO4,PLK4,SMO,TWIST1,ACSL4,ECE1,DVL2,SULF2,AKT1,SOCS3,ARHGAP35,SHROOM3,PTK7,ARNT,COBL,CTHRC1,NKX3-1,CCM2,SDC4,TGFBR1,JAG2,HOXB2,PPP2R3A,FZD6,SIX4,GBX2,CAPN2,E2F7,MGAT1,BMP7,FUT8,TFAP2A,ERCC2,MAP3K7,TTPA,HES1,TGIF1,UBE2A,PRICKLE1,BCL10,CNOT2,ACVRL1,FGFR2,SPINT2,TBX18,PKD2,ZMIZ1,SOX8,OSR1,FZD5,PLOD3,SHOX2,NCAPG2,FOXA1 |
| 3.017e-06 | -12.71 | Ser-Thr/Tyr_kinase_cat_dom | interpro domains | IPR001245 | 132 | 40 | 18293 | 2672 |
TNK1,LMTK3,EPHA4,RET,ERBB2,TESK2,TGFBR1,TEC,DDR1,FLT3,MERTK,IGF1R,MAP3K9,ERBB3,EPHB4,MAP3K7,SYK,RIPK2,TESK1,ACVR1C,ROR1,EPHA1,YES1,ILK,EGFR,TXK,EPHA10,INSR,FYN,JAK1,FGFR2,ACVRL1,AXL,LIMK1,PTK7,RYK,MAP3K11,KIAA1804,MLKL,JAK3 |
| 3.035e-06 | -12.71 | Signaling by EGFR | REACTOME pathways | R-HSA-177929 | 336 | 82 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,SH3KBP1,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,CBL,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,LRIG1,MAP3K11,NRG1,SPTBN5,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,ARHGEF7,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,DUSP1,RASGRF1,ADAM17,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 3.079e-06 | -12.69 | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP | 185 | 51 | 17758 | 2588 |
KLF2,LASP1,ACVR1,TM2D2,AVPI1,LGALS3,GNPDA1,UBASH3B,TSC22D3,HEXB,C5orf30,TGFBR1,MAP1LC3B,S100A2,BCAP31,SPP1,MGAT1,FBXO7,ADCK2,BRI3,IL17RA,SGK1,TNFRSF12A,USP38,SPRY2,TMBIM1,WBP5,TGIF1,C6orf1,MFI2,LONRF3,MAPKAPK3,NRBF2,PLEKHO1,KBTBD8,SLC17A5,LHFPL2,SNX12,STX3,RHOB,BCAR3,SCARB2,PEX5,CORO1C,LIMK1,WDR91,NRBP1,ZC3HC1,CCDC97,RRAGD,ABCG1 |
| 3.079e-06 | -12.69 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP | 185 | 51 | 17758 | 2588 |
SIGIRR,HECA,ACVR1,CCDC109B,UGP2,GALNT12,NDRG1,ITGA6,ARL4C,DGKA,GATA3,CYB561,DHRS3,RAB15,TIMP1,MGAT4A,IL6ST,FAM102A,WWP1,PIM1,MAST4,TIAM1,CPD,SOD1,CASK,FBLN5,TMEM43,MAPKAPK3,STAT4,PIK3R1,PRKCQ,TCF7,ULK2,PLEKHB1,TXK,OPTN,KDSR,PLCG1,FYN,ATP1A1,LDLRAP1,NGFRAP1,SEMA4D,LRIG1,INPP4B,FHL1,APBA2,TBC1D4,FAM134B,DOCK9,PCSK5 |
| 3.124e-06 | -12.68 | GSE14308_TH1_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH1_VS_INDUCED_TREG_UP | 190 | 52 | 17758 | 2588 |
IGFBP6,TRIM5,ERI2,C5orf30,PKP2,CUL1,TXNDC9,SORBS3,CAMK1D,CACNB4,SNX9,DUSP5,AIP,LBR,SDF4,RB1,TMEM87B,FAM46A,RINL,KCNK5,GALNS,FAM13B,ZIC5,REEP1,ANKRD12,NFU1,LRIF1,SPRY2,ODF2L,UFD1L,MOSPD2,LGALS8,SH3BGRL,VPS4B,FBXO8,EMP3,FAM133B,CASP4,TXK,PLCH1,TAPBP,KCNMB4,ACYP1,ACVRL1,SIPA1L1,NETO2,PPM1H,ZNF704,RHOBTB2,YOD1,SLC27A1,IRF7 |
| 3.124e-06 | -12.68 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | 190 | 52 | 17758 | 2588 |
PLEKHG3,REPS2,EPAS1,HAL,DNAJB11,EFHD2,FTH1,CTSZ,NOTCH2,GSTP1,ADAMTSL4,IL18R1,DUSP5,TTYH3,SGPL1,TMCC3,ATP6V0B,TM9SF2,RALB,CAPG,UBE2J1,CD9,IRF2,DGKG,C9orf72,NAGA,CYP1B1,MAP3K3,QSOX1,PDGFC,MCTP1,PLSCR1,LAP3,MPP1,PLEKHO1,TEP1,VAMP3,EMP3,CAPNS1,ZMPSTE24,SLC6A6,WDR11,SECTM1,DGAT2,DYSF,ZDHHC7,CTSA,PLXND1,ARSB,LTA4H,SLC31A2,AHR |
| 3.124e-06 | -12.68 | GSE3982_DC_VS_BCELL_UP | MSigDB lists | GSE3982_DC_VS_BCELL_UP | 190 | 52 | 17758 | 2588 |
LAMP1,SORT1,CDS2,GALNT12,SDC4,MRAS,SPSB1,CENPN,PPP2R3A,GBX2,ARHGEF10L,PDGFA,NOV,TGFBR3,PAPSS1,MITF,DAPK1,ADCK2,TACSTD2,ACOX2,EGLN3,SPRY2,CTH,PDGFC,ALDH2,AGPS,CTNNAL1,MPP1,ACO1,TNS1,POLD3,STX3,ULK2,RHEB,CD83,FUCA1,CTNS,WIPI1,P4HA2,SETD3,FAM114A1,RAB31,MAOA,ARRB1,AURKA,PLXND1,FZD5,ARSB,SLC31A2,SLC27A3,ACOT7,CSRP2 |
| 3.124e-06 | -12.68 | LTE2_UP.V1_DN | MSigDB lists | LTE2_UP.V1_DN | 190 | 52 | 17758 | 2588 |
DDX58,ANXA3,COL9A3,PARP12,LGR4,CALB2,TAP1,HERC5,CBLL1,SAMD9,EGR3,HERC6,LGALS3BP,SYTL2,BTG3,ADD3,IGF1R,SP100,ALG13,BHLHE41,TFAP2A,HSPA13,IFIT1,OAS3,LAMP3,GCA,HES1,ZNF84,PLSCR1,PRSS23,MICB,LPGAT1,USP18,FHL2,PRKAR2B,DNAJB14,IFIT3,C18orf8,MDK,PDLIM3,PTER,AMMECR1,NMI,MATN2,TDRD7,RAB31,IRF7,GEM,IFIH1,IFI6,PTGES,RPS6KA3 |
| 3.124e-06 | -12.68 | HOLLMANN_APOPTOSIS_VIA_CD40_UP | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_UP | 190 | 52 | 17758 | 2588 |
CD99,LTBP1,CCDC109B,TBC1D1,ATP8A1,C6orf106,GRK6,SBF1,CYP39A1,CDK14,FLII,SS18,RAC2,DPYSL2,CD22,PAK2,ADCK2,SRP54,ASH2L,PXMP4,MYBL1,SGCB,SNX10,PPP6R1,GM2A,CKAP4,SMC4,SYPL1,MRPS33,ALDH2,SHMT1,LAP3,TACC1,NR3C1,CLSTN1,EMP3,NUSAP1,RUNX3,EAF2,MEST,RNF19B,NFIB,RHEB,ENDOD1,GNAS,SLCO4A1,FNTA,ETS2,E2F1,HDAC1,ARPC2,NRGN |
| 3.131e-06 | -12.67 | single-organism carbohydrate metabolic process | biological process | GO:0044723 | 646 | 139 | 16441 | 2455 |
GAA,UGT8,SLC25A13,HEXB,NANS,GALM,MGAT5B,CALM2,INPP5E,MUC4,IL6ST,IMPAD1,PIK3CA,FUT1,AKR1B1,PPP1CA,TFG,TIPARP,MGAT5,SLC35C1,MGAM,GALNT7,SLC17A5,MCFD2,IDH1,ARF4,VCP,MAN2A2,AREG,DOLPP1,GNPTAB,DHTKD1,GLA,ITPKA,POMT1,PPP2R5D,DLAT,INPPL1,PPP1R2,PRKAA1,CALM3,ISYNA1,B4GALT4,ADAMTSL4,B4GALNT1,CALR,B3GALNT1,PFKL,BRAT1,STT3B,PHKG2,PPP6R1,TMED2,TRAK2,NAGPA,GFPT1,B3GNT7,CALM1,MGAT4B,GYLTL1B,PYGL,PDK3,PKM,GLT8D2,CYB5A,DHDH,ONECUT1,PRKAG2,UAP1,DGAT2,MDH1,CTSA,ALG2,B4GAT1,UGP2,GALNT12,WDTC1,PRKACA,EXT2,ART5,EPM2A,PER2,MUC16,GYS1,RPN2,GOT1,PHKA2,LMAN1,NAGA,GM2A,SIRT1,SEC23A,AKT1,PFKFB2,B3GALNT2,IRS2,ALDH5A1,DDOST,PPP1CB,B4GALT3,ST3GAL1,POMGNT2,MAN2B2,CMAS,GALK1,TRAPPC10,ENO2,MAN1A2,GNE,PDIA3,CTSZ,POMGNT1,FUT2,CTSC,PTEN,MGAT1,A4GALT,ALG13,MGAT4A,FUT8,UBE2J1,SLC35A1,GCNT1,B3GALT6,PGM1,B3GNT2,MLEC,GCLC,OGDHL,PARP4,C1GALT1C1,COL7A1,CRTC2,FUCA1,GALNT3,SERPINA1,CSGALNACT1,PGM2L1,GLB1 |
| 3.158e-06 | -12.67 | HALLMARK_COMPLEMENT | MSigDB lists | HALLMARK_COMPLEMENT | 195 | 53 | 17758 | 2588 |
PLA2G4A,CASP3,LGALS3,CTSB,GATA3,CALM3,PDGFB,GNB2,DUSP5,HPCAL4,CALM2,CD46,CA2,TIMP1,CTSC,PIK3CA,IRF2,PIM1,LGMN,CTSD,DGKG,S100A13,APOBEC3G,RASGRP1,ERAP2,LAMP2,DOCK4,GCA,TIMP2,CD55,KCNIP3,PLSCR1,LAP3,PLAUR,CASP9,CALM1,CDA,CR2,CASP4,CDK5R1,DGKH,MMP15,FYN,CASP7,SERPINA1,PRCP,IRF7,LTA4H,MAFF,USP16,IRF1,DOCK9,EHD1 |
| 3.158e-06 | -12.67 | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | MSigDB lists | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | 195 | 53 | 17758 | 2588 |
SUN1,FAM171B,PLEKHG3,ZSWIM5,PBX3,CYB561,IL18,TSPAN17,SYTL2,M6PR,PLS3,CD109,EPCAM,NPNT,KIF13B,OSBPL3,CYP2S1,FUT8,PIK3CA,ADAM15,TRPC1,ARNT2,TMEM37,LGMN,LRP11,GM2A,S100A6,DUSP1,DPYSL5,LOC81691,ADAMTS2,KIAA1841,CRIP2,STMN3,COL7A1,SLC17A5,ALCAM,ANKRD29,CASP4,GALNT3,CXXC4,PTPRJ,HLF,HPSE,DHRS13,H1F0,UEVLD,APPL2,RELL1,FBXO27,COBL,CSRP2,CD33 |
| 3.158e-06 | -12.67 | GSE360_CTRL_VS_L_MAJOR_DC_DN | MSigDB lists | GSE360_CTRL_VS_L_MAJOR_DC_DN | 195 | 53 | 17758 | 2588 |
CDK17,ENO2,PSME2,SOX9,SERPINB9,TAP1,SOD2,GMPR,NDRG2,PSME1,ZMYND10,TAF6L,DUSP5,H1FX,IER3,SGPL1,PLS3,TYMP,RGS12,TIMP1,LLGL2,LYPD3,FRYL,CABP1,OCRL,ATP8B1,PIM1,MARCH2,DLGAP1,FBLN5,IFITM3,SLC39A8,LITAF,CD40,RNF19B,NFIB,PITX2,IRS2,BTG1,SERPINA1,ETS2,CGREF1,SECTM1,BMP1,TDRD7,ATP1B3,ITGAV,HSPB1,IFI6,AHR,GAB1,IRF1,RRAGD |
| 3.182e-06 | -12.66 | MODULE_342 | MSigDB lists | MODULE_342 | 200 | 54 | 17758 | 2588 |
MYL9,PRSS8,FBLIM1,SORBS1,LMTK3,TSC22D3,FXYD3,GATA3,CCDC68,F11R,CRABP2,AIFM2,SDC1,LGALS3BP,CYP26A1,EPS8L2,SH2D4A,ELF3,EPCAM,SCNN1A,NUP210,MLPH,CDH1,CLDN4,CDH3,IGFBP2,TACSTD2,EGLN3,PXMP4,SSH3,PRSS23,KIAA0040,TMEM98,VWA1,GRTP1,PPP1R14C,PTGFRN,TP53I3,CYB5A,GALNT3,PTPRF,GPRC5B,CDCA5,SPINT2,FAM83D,SERPINB6,ANXA9,MAL2,F2RL1,HOOK1,E2F8,OCLN,FOXA1,XDH |
| 3.182e-06 | -12.66 | WIERENGA_STAT5A_TARGETS_UP | MSigDB lists | WIERENGA_STAT5A_TARGETS_UP | 200 | 54 | 17758 | 2588 |
KLF2,CDKN1C,FAM129B,CERCAM,NDRG1,CALB2,TGFBR1,CTSZ,FBXO6,DHRS3,PHLDA1,IL18R1,DUSP5,NCS1,SLC9A7,SNTA1,SPP1,CA2,GATA2,A4GALT,VASN,COL6A1,DAPK1,AK3,PIM1,RASGEF1A,HSPA2,CKAP4,LAMP3,P2RX4,AK4,UBAC1,TANC1,DPYSL4,TP53INP2,STK17B,C3orf58,CD83,GABARAPL1,MOSPD3,BTG1,NAAA,CTNS,SLC25A4,GNPTAB,P4HA2,SH3BP4,PGM2L1,MAOA,MAPK13,RAP1GAP,F2RL1,MIIP,ABCA1 |
| 3.231e-06 | -12.64 | JOHNSTONE_PARVB_TARGETS_2_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_DN | 313 | 76 | 17758 | 2588 |
CASP3,ETNK1,COMMD5,PDGFA,WEE1,CTGF,IMPAD1,SLC44A1,TECR,F2R,CPE,SEPHS1,ENPP4,SOAT1,DOCK4,SLC39A8,CDYL,KIF13A,GALNT7,ALCAM,STK17B,ZMPSTE24,AHRR,TRAM2,ENPP1,POPDC3,MAP2,MYLK,HDAC1,EFNA5,HS3ST3B1,TTC39C,F2RL1,ISOC1,RUNX2,TMTC3,FRMD6,RASA2,ADO,TGFBR1,TRIB2,SGPL1,SCML1,AKIRIN1,RASSF8,B3GALNT1,TPST1,RUNDC3B,ECI2,LIMCH1,ZMYM1,SLC35A1,SOCS5,PDGFC,NR3C1,OXR1,MRS2,FBXO9,PGBD1,KCTD20,PDIK1L,RANBP9,LEPR,DCP2,CYB5A,GLCE,STK17A,SLC35B3,SLC25A40,RAP2C,DCUN1D1,CBX5,TMEM14A,SHOX2,DEF6,DOCK9 |
| 3.340e-06 | -12.61 | cell communication | biological process | GO:0007154 | 5288 | 887 | 16441 | 2455 |
DOC2A,ADD1,IL15RA,GRIK2,TRIM5,DNAJC3,RET,XIAP,NRG2,IL18,BAIAP3,SYTL4,KIF26A,CA8,SPSB1,CARD10,GRM5,TP73,CALM2,DAPK2,ZYX,RGS12,ARHGAP42,PSMD1,TGFBR3,DNM2,CLDN4,CRY2,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,IL10RB,TIPARP,NEK4,TNIP1,CDA,TFAP2C,KDELR3,PRKAR2B,ARF4,LCP1,ABR,PGF,CARHSP1,PLCG1,DNM1L,LIMK1,MYLK,MAP3K11,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,ARF6,HSPB1,STARD13,GAB1,SCN5A,NUAK1,SEC61G,ITGA6,SOX9,RAB23,ZNRF3,GPSM2,MERTK,HPCAL4,LMNA,ATG4A,TFAP4,RAC2,MEGF8,FLRT3,FAM13B,RANBP1,MAP3K9,MYDGF,PANX2,CNGA1,MAPK7,NCAM1,DGKG,NUP85,PAQR7,MAPKAPK3,SALL4,STAT4,ERO1A,SHARPIN,FHL2,CALCRL,NPHP3,ILK,ELK1,PSMA4,GNA11,RHOB,STK17A,PTPRF,IL1R1,NCOA3,FNTA,HTT,SEMA4D,ITPR1,OSMR,STK39,GDF11,NDE1,ARPC2,TRPC3,NUP58,RPS6KA3,DOCK9,DMPK,ARHGAP11A,NQO1,LFNG,CD82,INPP5D,PKP2,IL13RA1,MAPK4,NUF2,GRK6,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,CCND1,CDH1,SP100,SH3BP1,DACT1,ENPP5,TAX1BP3,RTKN2,ARL4D,DLG3,RASGEF1A,RAB27B,SCN3A,MX1,SEC61B,RIPK2,FZD4,RAB38,GIGYF1,IRS2,SLC9A6,AXL,WFS1,CORO1C,SIPA1L1,WWTR1,INPP4B,TRABD2A,RGS14,ARNT,MAPK12,CTHRC1,TNRC6C,NKX3-1,TAOK2,HSP90B1,MPZL1,TRAF2,SDC4,RASSF7,CCM2,FLOT1,BTN3A1,PDIA3,PKN1,PLPPR4,ZNF219,KCNC4,IFT27,NFAT5,ICAM1,SGPL1,CTNNBIP1,DIRAS3,ANK1,PDCD10,IRAK1,ITGB8,KNDC1,MCF2L,GPC3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,MAPK11,S100A6,HCN3,AMOTL2,CTNNAL1,BCL9,RAPGEF2,PIK3R1,GRIN1,NEURL1B,SKA1,TXK,CNTNAP1,KIAA0141,ACVRL1,NR1D2,SYT7,RAB11FIP2,NR4A3,SSNA1,CENPE,ITGAV,NUP37,USF2,CD81,WDR45B,FOXA1,MYL9,SIGIRR,UNC93B1,BCAM,TNK1,EPAS1,AGRN,EPHA4,NDC80,NDRG2,DNAJB11,F11R,TEX2,ITPR2,PDGFB,SDC1,SPTB,RPS6KA2,NUP210,CTNNB1,SHC3,IL6ST,ARL1,MITF,PSMC2,DUSP10,TNFRSF18,NTN4,SCARA3,THRB,PLK1,KCNIP3,MCTP1,MARK1,CELSR2,CR2,EZR,ARFRP1,VCP,RHEB,PLEKHB1,OPTN,TRIM9,PLCH1,KCNMB4,WIPI1,CTNND1,KPNA2,PIK3C2B,TC2N,MYL12B,RRAGD,PRKAA2,RUNX2,BMF,RASA2,HLA-F,PDCL,PSMD7,RACGAP1,CNTNAP2,NCKAP1,RAB6A,DOCK11,FBLN1,DHRS3,IL18R1,ANO1,BMP2,RB1,VASP,IGF1R,KIF13B,FRAS1,PAK2,SELK,MDFIC,PIM1,NTN1,WNT3A,PLCB2,PSMA5,DPYSL5,PCDH1,RGMB,CORO2A,STRADB,TCF7,SCRIB,PDK3,IFIT3,CDK5R1,NMT2,RASGRP2,MAPKAPK2,PVRL2,PHLPP2,ITGA7,CSF1,LTBP2,PLD1,SEMA3A,IFI6,RNF146,KCNAB3,NF2,FOXM1,TP53,DGKA,P2RX7,RHPN2,CCDC68,ERBB2,RASGRP3,STIL,BCAP31,SYTL2,IER3,CDK14,TTC21B,PDGFA,ATP6V0B,PLCG2,BCL6,CDH3,OAS3,NOTCH3,SCN2A,CTDSP2,DVL2,CTH,SULF2,SIRT1,CLCN3,MBP,AKT1,CDC20,PTGER4,MYL12A,DUOX1,DNAJC10,ATP1A1,IDE,PTPRJ,RBL1,PTK7,STK38,PSMD3,MAOA,EFNA5,IRF7,ANXA9,SYT13,ARHGAP4,GSDMD,ZMAT1,PINK1,CPEB4,ADGRG1,TAB3,CTSB,DAP,GNAL,MCTP2,ERCC6L,CDCA8,GABRG2,PSMD10,GDF15,JAG2,CRABP2,AIP,FZD6,IL22RA1,PPP2R3A,DNAJB9,NRP2,M6PR,CDK16,SGK1,IL17RA,TRIM21,BUB1,CPLX1,TSPAN13,SYK,CAMK2G,DUSP1,DLGAP1,P2RX4,HES1,RHOA,PSMB4,NR3C1,IFITM3,PLAUR,AMFR,LITAF,PPARA,MAML2,PELI3,AKAP3,BBS2,BCAR1,MAPK8IP1,DGKE,CD83,PRDX4,BCL10,DDAH1,FAT4,SCG2,TWSG1,NMI,FGF18,E2F1,PKD2,ICOSLG,NDFIP1,ARHGEF9,PTGES,ZBTB33,ARHGEF4,LAMP1,ACVR1,TXN,LGR4,HSPG2,KLC2,CUL1,GATA3,PSME1,PDGFRL,PLXNA1,PJA2,SLC20A1,CENPN,NCS1,PICK1,PAK6,CTGF,ELMO2,IL31RA,PIK3CA,KCNS3,ATRNL1,IRF2,TACSTD2,TFG,RCAN3,METAP2,ACVR1C,CASP9,BNIP3L,AGO4,AURKB,SAV1,ZFAND5,ULK2,RAB2B,SGPP1,AREG,TBX1,PLK2,SH2D3C,NKD1,MAPK13,EIF4EBP2,UNC5B,TRAF5,F2RL1,FGD1,DDX58,SEMA6B,THEMIS2,HLA-E,DGKQ,PRKAA1,AKAP17A,NOTCH2,SLC1A3,APBA1,TNFRSF19,TSPAN7,MESDC2,CALR,ITGA3,RALGPS2,PIK3AP1,CYR61,PPP4R1,MSH2,PRKG1,OPN3,DAPK1,SORL1,OSTF1,CD70,TNFRSF12A,CACNA1D,PIKFYVE,MAST4,SYTL3,GPR161,EEF1D,RIMS2,SOCS5,GFPT1,PRODH,KCNJ12,B9D2,MICB,CALM1,AMER1,DCHS1,ANO6,EPHA1,CYFIP2,KDM3A,ANTXR1,STX3,RASA1,PDE11A,FAS,DGKH,GABRD,PRKAG2,PELI2,CSNK1G1,MPP2,APPL2,PIAS2,ARAP1,CABIN1,NR4A2,EFNA1,MAP3K5,IFIH1,IRF1,SPRED1,REPS2,TCTN2,TRIP10,S100A11,RALBP1,THRA,RPS6KA1,IQGAP1,NDRG1,BCL2L1,EGR3,CD274,DDR1,FLT3,GNB2,EPS8L2,ZFYVE9,NOV,APLP2,CCNA2,RALB,DOK4,CDKN1B,DAB2IP,PDE4D,EPHB4,IFIT1,TSPAN1,LGMN,MED30,NR2C1,ATG4D,SEMA3B,DOCK4,DMTN,PRKCQ,ATP1B1,PYGO1,ASB13,CBL,ITPR3,ALCAM,FZD7,EPHA10,FYN,JAK1,PPP2R5A,NGFRAP1,STK26,TSPAN18,KIAA1804,STAT1,PPP1CB,SLC27A1,RAB29,NRG1,NR3C2,PRKAR1A,ARHGEF3,IGFBP6,DEPDC1,CENPI,EPS8,ARL4C,HERC5,GPR180,PLD2,SPDL1,FGF19,EFNB1,LGALS3BP,TEAD3,ADGRB2,HLA-A,CKAP5,RND1,RASSF8,E2F7,GNB5,PTEN,FJX1,FUT8,PRC1,CD9,SGK3,SLC44A2,ERBB3,MAP3K7,CITED2,CNPY3,TRIM62,SPRY2,NCOA2,MSH6,FARP2,RASGRF1,TGIF1,PDGFC,CASK,ALDH2,ARHGEF28,ZWINT,ARAP2,MPP1,FURIN,DIAPH2,YES1,FOS,GPLD1,RGS9,FGFR2,RIN3,RYK,RABL6,GRIN2D,LRRK1,GPER1,FZD5,MELK,RGMA,CCNC,LTBP1,CASP3,CAMKK1,UBE2Q1,KIF2C,CACNB4,MAP1LC3B,DNER,KREMEN1,TRIM68,PTCHD4,SH3KBP1,HTR1D,EPCAM,ZFYVE16,RAB15,ZCCHC12,DPYSL2,TSPAN6,SIVA1,DLG1,AKR1B1,RAB20,CTTN,MYH14,PTPRE,IL1RAP,RASGRP1,CYP1B1,SOD1,CXXC5,TRIM8,CENPA,ITCH,USP18,ARHGDIB,ROR1,ADRBK2,STK17B,EDNRA,CXXC4,MDK,GPRC5B,KCNK1,MADD,CAB39,ADIPOR1,RAP1GAP,NRGN,APBA2,PPP2R5D,PSMC1,NR2C2,PCSK5,GRN,ARAP3,LRRFIP2,PPP1R12A,ETV5,ASB9,ATP6V1E2,CALM3,TEC,PHLPP1,DUSP5,NOXA1,CA2,LRRN2,KCNN4,OCRL,DIAPH2-AS1,PRKCI,FNIP1,KNTC1,HLA-C,NPTN,C10orf54,ZRANB1,GAD1,CCDC88A,MDFI,ELK3,PDE5A,EGFR,RHPN1,GNAS,BCAR3,ONECUT1,TSC1,INSR,PLPP3,NFKBIA,RAB31,RHOBTB2,NXPH4,YOD1,JAK3,TOB1,RARG,COL16A1,DRD1,GAS2L1,SORBS1,SPC25,IL15,SLC2A8,PSME2,SOD2,PDIA5,IL27RA,MRAS,EXT2,ARHGEF16,SS18,ARTN,KIF14,SMO,GOT1,DIXDC1,NFKB2,F2R,PDIA6,FRS3,CHP1,MAP3K3,BAG4,KREMEN2,PTPRU,ERBB2IP,CD40,DUSP4,DOCK5,CDC25C,CASP4,MAP3K6,ARHGAP35,SOCS3,ALDH5A1,STAT6,SECTM1,CANT1,TLE1,RCAN2,SPTBN5,PLXND1,SGOL1,ABCA1,LIFR,SORT1,ARHGEF11,ARHGEF7,CIT,LRP4,TGFBR1,AES,NOTUM,ITGA2B,XPR1,HMGXB4,SYDE2,HDAC9,IL17RB,ADRBK1,ADORA1,BMP7,ZDHHC13,BRD7,IQGAP3,MYO5A,SYPL1,RAB3B,ADAM17,CENPC,WNT10B,DEPDC4,NR4A1,NDRG3,FOXL1,LEPR,ARHGAP24,CTSL,HLA-B,CD8A,CASP7,RND3,CTSV,RAP2C,UBE2D2,DTX4,UACA,ARRB1,GEM,ATP6V1C1,SOX8,L1CAM,AHR,CD33,SNPH,NGEF |
| 3.358e-06 | -12.60 | Signaling by FGFR2 | REACTOME pathways | R-HSA-5654738 | 316 | 78 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,CBL,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 3.366e-06 | -12.60 | CHYLA_CBFA2T3_TARGETS_UP | MSigDB lists | CHYLA_CBFA2T3_TARGETS_UP | 372 | 87 | 17758 | 2588 |
UNC93B1,CCDC109B,S100A11,TSC22D3,PPFIBP2,GMPR,P2RX7,MGST2,RALB,PLCG2,ATRNL1,GYS1,VAT1,NOTCH3,EGLN3,RAB27B,F2R,KRT80,GCA,MCTP1,CXXC5,KCNIP3,DSTN,SEPT6,CDA,MGAM,TMEM144,PRKCQ,ARHGDIB,IDH1,SPNS3,TCN2,LCP1,ATP13A2,CXXC4,PTPRJ,HPSE,TRIM45,NRG1,EIF4EBP2,TTC39C,KDELC2,ANXA3,ARHGEF3,BACE1,CYP2J2,UBASH3B,ELOVL7,MTL5,HOXB2,GBX2,CALR,RASSF8,RALGPS2,CTSC,DRAM1,SLC35B4,TNFRSF12A,ALPK1,RAG1,GFI1,MAST4,TTPA,TLE6,SUN2,PRODH,CASK,HPS3,PARD3B,LPGAT1,CDK5R1,RHOB,RASGRP2,SOX13,SLCO4A1,PELI2,C1orf21,RIN3,APPL2,RAB31,UACA,SH3BGRL2,PLOD3,SERPINB1,TMEM173,DOCK9,ABCG1 |
| 3.371e-06 | -12.60 | LOPEZ_MBD_TARGETS | MSigDB lists | LOPEZ_MBD_TARGETS | 900 | 180 | 17758 | 2588 |
CCNI,ST13,HSPG2,EPAS1,CPT2,FBXO2,NRG2,PLA2G16,LTBP3,BTG3,PCNA,CTNNB1,RGS3,SIVA1,PSMC2,SERINC2,TUBG1,CTTN,PPP1CA,TFG,IL10RB,TUBA4A,SOD1,BNIP3L,EZR,TP53I3,CDK1,RHEB,CARHSP1,AGPAT2,AREG,MAP3K11,BMP1,PIEZO1,TRAF5,PPP2R5D,MYL12B,CAPN1,ANXA11,CDKN1C,HLA-E,HLA-F,RAB6A,HES2,RSAD1,RABGGTA,GNS,SPP1,DAZAP1,IGF1R,CYR61,NECAB3,FBXO7,TBCD,MSH2,ZNF692,CD70,AHCY,NCAM1,EEF1D,PSMA5,KDELR1,DNAI1,QSOX1,ELK3,CORO2A,ANO6,ZNF320,MYBL2,KCTD20,VWA1,RNF113A,NPC2,EPHA1,CYFIP2,PSMA4,RHOB,PTPRF,IL1R1,SCARB2,FNTA,SEMA4D,NFKBIA,RAB31,CCNB2,IFI6,MTM1,SORBS1,CAPN12,LFNG,SLC2A8,PSME2,RPS6KA1,THRA,PTTG1,CTDSPL,HDAC11,IRX4,IL27RA,MICALL2,APLP2,ATP6V0B,ZNF75D,DOK4,GOT1,EPHB4,LGMN,PPIF,SEC61B,RIPK2,PTPRU,DRAP1,BTBD19,GLO1,BCL7B,C15orf39,ALDH3B1,ALDH5A1,NGFRAP1,AXL,SECTM1,OVOL1,PPP1CB,KDELC2,CD63,SDC4,BLVRB,NUCB2,SEPP1,GSTP1,FGF19,AIP,TOP2A,PDCD10,ADD3,IRAK1,PPP1R10,CDK16,CTSC,GPC3,FDXR,SGK1,IGFBP2,BUB1,ABCD1,SGCB,MED22,TLE6,FAH,TGIF1,RHOA,PSMB4,IFITM3,PAPD7,GUSB,NR4A1,LITAF,UBE2A,UBAC1,YES1,FNDC3A,AIF1L,NPDC1,RNPEP,KIF11,DDX23,CNTNAP1,DCTN6,HLA-B,BTG1,SERPINA1,CCDC6,HNRNPH2,PLA2G15,SPINT2,UBE2D2,ERAP1,SSNA1,UBE2C,SHOX2 |
| 3.409e-06 | -12.59 | Pkinase_Tyr | pfam domains | PF07714 | 129 | 40 | 16629 | 2504 |
TNK1,LMTK3,EPHA4,RET,ERBB2,TESK2,TGFBR1,TEC,DDR1,FLT3,MERTK,IGF1R,MAP3K9,ERBB3,EPHB4,MAP3K7,SYK,RIPK2,TESK1,ACVR1C,ROR1,EPHA1,YES1,ILK,EGFR,TXK,EPHA10,INSR,FYN,JAK1,FGFR2,ACVRL1,AXL,LIMK1,PTK7,RYK,MAP3K11,KIAA1804,MLKL,JAK3 |
| 3.430e-06 | -12.58 | TSAI_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | TSAI_RESPONSE_TO_IONIZING_RADIATION | 147 | 43 | 17758 | 2588 |
GRN,CCNE2,CCNI,NFKBIE,CDKN1C,LGALS3,RPS6KA1,TSC22D3,PTTG1,GDF15,RB1,PCNA,TGFBR3,PLCG2,COL6A1,RANBP1,MSH2,SGK1,RFX5,NFKB2,FAM134C,MDFI,PLK1,DDB2,TGIF1,NFE2L1,KIF20B,SNAPC2,CCNF,TP53I3,CDK1,FAS,DPYSL3,CD83,NCOA3,BTG1,AXL,NFKBIA,STAT1,NR4A3,PLOD3,UBE2C,AHR |
| 3.441e-06 | -12.58 | ESC_J1_UP_EARLY.V1_UP | MSigDB lists | ESC_J1_UP_EARLY.V1_UP | 171 | 48 | 17758 | 2588 |
PRSS8,SERPINE2,IL15,NDRG1,THRA,FXYD3,CD82,TRIB2,FLT3,MOCS1,RB1,TYMP,SESN3,SCNN1A,ST5,NECAB3,CYP2S1,A4GALT,BMP7,ENPP5,NEK2,CDKN1B,CDH3,C10orf54,TSPAN1,KANK3,NAGA,TLE6,P2RX4,PIGC,ADCK3,CORO2A,PIK3R1,PTGER4,LOXL2,PCTP,NAAA,C19orf66,GDE1,P4HA2,MPP2,RPL22,WBSCR27,CPPED1,RAB3IL1,FAM134B,CD33,ABCG1 |
| 3.441e-06 | -12.58 | PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP | MSigDB lists | PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP | 171 | 48 | 17758 | 2588 |
CCNE2,PLSCR4,UPF3B,FAM199X,CENPI,SUDS3,NUF2,CCNL1,B4GALT4,NUP62CL,BARD1,PSIP1,MECOM,ELF3,SCML1,MYO5C,ZFX,E2F7,NUP210,CENPJ,NEK2,ATP8B1,KNTC1,DDX59,ODF2L,KCTD3,FGFR1OP2,SMC4,NEK4,CASK,ERMP1,POLD3,PDIK1L,CDK1,KLHL2,ETS2,RBL1,NR1D2,HOXA9,ZNF367,PRPS2,KIAA1804,NR4A2,DONSON,GRAMD1C,PER3,GEN1,E2F8 |
| 3.452e-06 | -12.58 | CTTTAAR_UNKNOWN | MSigDB lists | CTTTAAR_UNKNOWN | 918 | 183 | 17758 | 2588 |
TMEM184B,EPAS1,KLC2,SUDS3,FBXO2,LMCD1,PHOSPHO1,CDIPT,VASH1,SH3KBP1,CDKN2C,SIPA1L2,RAB15,CTNNB1,ELMO2,IMPAD1,DPYSL2,KLF3,SLC44A1,MITF,DLG1,STEAP2,AKR1B1,ATRNL1,DUSP10,ASH2L,STK35,THRB,TNIP1,CELSR2,ACVR1C,SERTAD4,CBX6,PRKAR2B,PIF1,PPP1R14C,LDB2,IDH1,SEC14L2,ANKRD10,MAP2,ZNF367,MAP3K11,PIK3C2B,NFKBIZ,UNC5B,NRGN,F2RL1,HOXC13,NR2C2,INPPL1,CHCHD7,FXYD3,ETV5,ATP6V1E2,SLC1A3,DOCK11,TNFRSF19,BMP2K,LMNA,MECOM,CALR,FLII,VASP,ITGA3,CYR61,ZNRF2,BHLHE41,FAM13B,PPP4R1,OPN3,AHCY,RFX5,CACNA1D,RIMS2,EPB41L5,CYP26B1,PIGC,HPS3,USP31,MAPKAPK3,MGAT4B,HMG20B,CALCRL,TCF7,EPHA1,PDIK1L,ZDHHC3,MUM1L1,RHOB,C11orf45,XKRX,MMP15,PELI2,SPAG7,MPP2,RHOBTB2,SEMA3A,TOB1,SPRED1,NCKAP5,SLC2A4,SORBS1,FAM92A1,HOXB7,GPR107,CAST,CERCAM,OSR2,PRKACA,KTN1,ZFYVE9,CDK14,APLP2,LMO4,VAT1,DAB2IP,DLG3,ETHE1,EGLN3,ZNF365,SEMA3B,SEPHS1,CPD,SSH3,ERBB2IP,NFIX,ATP1A1,PEX5,STX10,AXL,MMP17,SLC9A6,KLF5,PRIMA1,C1orf43,REEP4,GEN1,NR3C2,NDST3,CMTM4,MAMDC2,BIN1,PACSIN2,RBM24,MACC1,GCAT,HAPLN3,ARL4C,PBX3,ZNF219,SRPX2,PPP2R3A,SCML1,FOXP2,CTNNBIP1,MDM1,ADD3,PPP1R10,CDK16,LYPD6,MGAT4A,FAM20B,FUT8,TOX2,TAGLN2,C12orf75,MED22,GCNT1,TGIF1,BCL9,FAM109A,MAP1B,PITX2,HLA-B,NUCB1,ABCB1,OTUB2,FBXO44,ZBTB33,SRSF9,SNPH,JARID2 |
| 3.526e-06 | -12.56 | SASSON_RESPONSE_TO_FORSKOLIN_DN | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_DN | 88 | 30 | 17758 | 2588 |
LOC81691,DYRK3,CDKN1C,ATP9A,ARL4C,TP53,TP53I11,NPC2,CYFIP2,ILK,DHRS3,CASP4,CARD10,CDK14,STK17A,ARHGAP35,PTPRF,ITGA3,PDLIM3,AXL,STAT1,DAPK1,SH3BP4,RAB31,ACTA2,CTNND1,RGS5,PIK3CD,GEM,PTPRE |
| 3.582e-06 | -12.54 | RHODES_UNDIFFERENTIATED_CANCER | MSigDB lists | RHODES_UNDIFFERENTIATED_CANCER | 67 | 25 | 17758 | 2588 |
GCLM,CENPA,SEC61B,DLGAP5,FOXM1,CDC20,TAP1,MYBL2,KIF23,GGH,KIF2C,GPSM2,CCNB1,CDK1,PRDX4,TOP2A,CCNA2,PCNA,KIF14,CKS1B,KPNA2,UBE2C,MELK,RAD21,CKS2 |
| 3.593e-06 | -12.54 | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | 181 | 50 | 17758 | 2588 |
BIN1,SIGIRR,HECA,ACVR1,HAPLN3,GALNT12,TRAF2,CD82,EPHA4,GATA3,AES,ISYNA1,ANO9,PHF1,PSIP1,TMEM63A,KIF22,WWP1,FAM84B,TECR,RCAN3,MAST4,RASGRP1,CAMK2G,SUSD3,CASK,FBXL16,PAPD7,STMN3,PRKCQ,ESYT1,ITPR3,KCTD2,OPTN,PRIM1,SFXN1,PLCG1,KLF12,AMMECR1,LRIG1,INPP4B,FAM117A,TTC39C,TRAF5,ST3GAL1,TMEM14A,TC2N,CBX7,DOCK9,PHC1 |
| 3.595e-06 | -12.54 | LY_AGING_OLD_DN | MSigDB lists | LY_AGING_OLD_DN | 55 | 22 | 17758 | 2588 |
PLK1,CENPA,FOXM1,CDC20,MYBL2,KIF23,KIF2C,PKMYT1,CCNF,CCNB1,BARD1,KIF11,CKAP5,PTGS2,CCNA2,PCNA,CTSC,KIF14,RANBP1,PSMC2,CKS1B,UBE2C |
| 3.615e-06 | -12.53 | DH-domain | interpro domains | IPR000219 | 71 | 26 | 18293 | 2672 |
PLEKHG3,RASGRF1,ARHGEF28,ARHGEF3,FARP1,ARHGEF11,ARHGEF7,SPATA13,ARHGEF40,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,MCF2L,PLEKHG1,FGD6,TIAM1,ALS2CL,ARHGEF9,NGEF,ARHGEF4,FGD1,FARP2 |
| 3.639e-06 | -12.52 | positive regulation of intracellular signal transduction | biological process | GO:1902533 | 973 | 196 | 16441 | 2455 |
TXN,TRIM5,EPHA4,ARFGEF1,LMCD1,NRG2,GATA3,PSME1,IL18,NENF,SEPT4,PDGFB,SLC20A1,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,PSMD1,CTNNB1,CTGF,NPNT,SHC3,IL6ST,TSPAN6,PSMC2,IL31RA,AKR1B1,TNFRSF18,TFG,S100A13,RASGRP1,CYP1B1,SOD1,CXXC5,TRIM8,PRKRA,CDK1,RHEB,PLCG1,GPRC5B,HPSE,DNM1L,ANKRD6,PLK2,TBX1,MADD,FAM110C,NOD2,MAP3K11,PRKCDBP,ADIPOR1,UNC5B,TRAF5,F2RL1,PSMC1,GAB1,RRAGD,BMF,RASA2,SOX9,PRKAA1,PSMD7,CALM3,SORBS3,NOTCH2,TNFRSF19,DUSP5,IL18R1,KIAA1161,BMP2,IGF1R,PIK3AP1,MAP3K9,MDFIC,MYDGF,NCAM1,PSMA5,EEF1D,MDFI,MAPKAPK3,CALM1,SHARPIN,PDE5A,ILK,PSMA4,EGFR,RASA1,FAS,GNAS,MAPKAPK2,INSR,SEMA4D,HTT,PELI2,CSF1,EFNA1,MAP3K5,JAK3,XDH,SPRED1,AVPI1,IL15,PSME2,TP53,ERBB2,P2RX7,RASGRP3,BCL2L1,FLT3,BCAP31,PDGFA,ST5,DAB2IP,RASGEF1A,F2R,DVL2,FRS3,CTH,MAP3K3,SIRT1,TIMP2,BAG4,RIPK2,FZD4,S100A4,PRKCQ,CBL,CD40,MAP3K6,FZD7,IRS2,PTGS2,FYN,PTPRJ,JAK1,AXL,PSMD3,SECTM1,KIAA1804,CANT1,NRG1,SPTBN5,PINK1,TAOK2,NKX3-1,ADGRG1,TAB3,TRAF2,PSMD10,TGFBR1,PKN1,FGF19,ICAM1,PDCD10,ADORA1,IRAK1,PTEN,BAX,ZDHHC13,PLEKHF1,SLC44A2,BUB1,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,TRIM62,CAMK2G,P2RX4,RASGRF1,HES1,RHOA,PSMB4,RAPGEF2,RC3H2,GRIN1,LITAF,BCL10,CD8A,BANK1,FGFR2,FGF18,RYK,ARRB1,GRIN2D,PKD2,GPER1,LRRK1,FZD5,CD81,NDFIP1,L1CAM |
| 3.647e-06 | -12.52 | DOANE_RESPONSE_TO_ANDROGEN_DN | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_DN | 231 | 60 | 17758 | 2588 |
CCNE2,PRSS8,LTBP1,ARHGEF3,ENO2,TRAF2,EPHA4,EPS8,GATA3,FAM198B,CRABP2,HERC6,DHRS3,PRKACA,FBLN1,PSIP1,HLA-A,APOBEC3B,CDKN2C,RAB15,GNB5,ZDHHC13,PLK4,ARVCF,IGFBP2,MXD3,TINAGL1,CACNA1D,SMYD5,TIAM1,MAST4,HP1BP3,SNX7,PLEKHA6,KREMEN2,PLSCR1,IFITM3,MPP1,CDYL,WHSC1,DUSP4,CYFIP2,CDK1,ARHGAP35,PEX5,CASP7,PLOD2,NGFRAP1,PELI2,SIPA1L1,ITPR1,PLXND1,ANXA9,EPB41L4A,TRAF5,ARNT,E2F8,CYBRD1,SNPH,PHC1 |
| 3.649e-06 | -12.52 | chemotaxis | biological process | GO:0006935 | 789 | 164 | 16441 | 2455 |
MYL9,AGRN,EPHA4,NRG2,GATA3,PSME1,PLXNA1,CACNB4,PDGFB,CMTM6,SPTB,CALM2,TYMP,PSMD1,RPS6KA2,SHC3,ELMO2,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,MYH14,SEMA3G,PIK3CD,TIAM1,RASGRP1,RNF165,EZR,DPYSL3,PLCG1,LIMK1,UNC5B,PSMC1,MYL12B,SEMA6B,SCN5A,LGALS3,RASA2,PSMD7,CALM3,DUSP5,CORO1B,SPP1,RAC2,VASP,CYR61,FLRT3,PAK2,COL6A1,CACNA1D,NCAM1,NTN1,WNT3A,NUP85,PSMA5,DPYSL5,RGMB,CALM1,ANO6,SCRIB,EPHA1,DPYSL4,PSMA4,NFIB,RANBP9,RHOB,EGFR,CDK5R1,RASA1,SEMA4D,MATN2,PITPNA,EFNA1,PLD1,B4GAT1,ARPC2,TRPC3,JAK3,SEMA3A,RPS6KA3,KLF7,SPRED1,RPS6KA1,PSME2,RALBP1,ERBB2,RASGRP3,EGR3,ARHGEF16,PDGFA,NOV,ARTN,DAB2IP,EPHB4,PDE4D,RASGEF1A,DLG3,ETV4,FRS3,SEMA3B,DOCK4,COL6A2,PRKCQ,ALCAM,DAG1,MYL12A,ARHGAP35,CMTM7,EPHA10,IRS2,FYN,PTPRJ,JAK1,PSMD3,NRG1,SPTBN5,EFNA5,PLXND1,CMTM4,COL9A3,ARHGEF11,ARHGEF7,PSMD10,COL4A5,EFNB1,FGF19,NRP2,ITGA2B,NEO1,GBX2,RND1,KIF5B,CXCL16,ANK1,BMP7,ERBB3,SYK,CAMK2G,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,RAPGEF2,PLAUR,NR4A1,GRIN1,YES1,BCAR1,ABLIM2,CNTNAP1,SCG2,FGFR2,FGF18,PGRMC1,RYK,NR4A3,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 3.649e-06 | -12.52 | taxis | biological process | GO:0042330 | 789 | 164 | 16441 | 2455 |
MYL9,AGRN,EPHA4,NRG2,GATA3,PSME1,PLXNA1,CACNB4,PDGFB,CMTM6,SPTB,CALM2,TYMP,PSMD1,RPS6KA2,SHC3,ELMO2,DPYSL2,PSMC2,DLG1,TRPC1,NTN4,MYH14,SEMA3G,PIK3CD,TIAM1,RASGRP1,RNF165,EZR,DPYSL3,PLCG1,LIMK1,UNC5B,PSMC1,MYL12B,SEMA6B,SCN5A,LGALS3,RASA2,PSMD7,CALM3,DUSP5,CORO1B,SPP1,RAC2,VASP,CYR61,FLRT3,PAK2,COL6A1,CACNA1D,NCAM1,NTN1,WNT3A,NUP85,PSMA5,DPYSL5,RGMB,CALM1,ANO6,SCRIB,EPHA1,DPYSL4,PSMA4,NFIB,RANBP9,RHOB,EGFR,CDK5R1,RASA1,SEMA4D,MATN2,PITPNA,EFNA1,PLD1,B4GAT1,ARPC2,TRPC3,JAK3,SEMA3A,RPS6KA3,KLF7,SPRED1,RPS6KA1,PSME2,RALBP1,ERBB2,RASGRP3,EGR3,ARHGEF16,PDGFA,NOV,ARTN,DAB2IP,EPHB4,PDE4D,RASGEF1A,DLG3,ETV4,FRS3,SEMA3B,DOCK4,COL6A2,PRKCQ,ALCAM,DAG1,MYL12A,ARHGAP35,CMTM7,EPHA10,IRS2,FYN,PTPRJ,JAK1,PSMD3,NRG1,SPTBN5,EFNA5,PLXND1,CMTM4,COL9A3,ARHGEF11,ARHGEF7,PSMD10,COL4A5,FGF19,EFNB1,NRP2,ITGA2B,NEO1,GBX2,RND1,KIF5B,CXCL16,ANK1,BMP7,ERBB3,SYK,CAMK2G,FARP2,RASGRF1,RHOA,B3GNT2,ARHGEF28,PSMB4,RAPGEF2,PLAUR,NR4A1,GRIN1,YES1,BCAR1,ABLIM2,CNTNAP1,SCG2,FGFR2,FGF18,PGRMC1,RYK,NR4A3,GRIN2D,ITGAV,L1CAM,NGEF,RGMA |
| 3.650e-06 | -12.52 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP | 186 | 51 | 17758 | 2588 |
SUN1,BIN1,LZTFL1,PNISR,PINK1,TRAPPC10,HEBP1,ATP8A1,PPFIBP2,NDRG2,AES,SORBS3,ISYNA1,TRIB2,ERP29,LTBP3,RSAD1,RGS12,LLGL2,STIM1,LYPD3,A4GALT,MCF2L,KLF3,DLG1,VAT1,WWP1,KLF9,ARL4D,PHKA2,OSBPL7,TPCN1,REC8,ADCK3,LITAF,STMN3,NPC2,SRSF5,ERBB2IP,ITPR3,TRAM2,MSL1,ATP1A1,KIAA0141,CSGALNACT1,TCEAL4,TMEM8B,TMEM159,KLF7,SNPH,PHC1 |
| 3.650e-06 | -12.52 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | 186 | 51 | 17758 | 2588 |
LGALS3,CDKN1C,DNAJC3,NENF,MORF4L2,CRABP2,NUCB2,SDC1,DUSP5,SDF4,EPS8L2,ARHGEF16,LMNA,DNAJB9,CHPF,GBX2,TP73,BTG3,TIMP1,ARL1,FICD,CST3,RRBP1,HSPA13,TFG,NTN1,ITM2C,KDELR1,SEMA3B,PODXL2,RAPGEF2,KDELR3,C1GALT1C1,BLVRA,MCFD2,RHEB,SOCS3,FUCA1,MDK,INSR,RBM47,WIPI1,RCBTB2,PRCP,MMP17,NFKBIA,ARFGAP3,ADIPOR1,FAM149A,PDXK,MAPK12 |
| 3.655e-06 | -12.52 | VANHARANTA_UTERINE_FIBROID_DN | MSigDB lists | VANHARANTA_UTERINE_FIBROID_DN | 63 | 24 | 17758 | 2588 |
LTBP1,KLF2,NR3C1,NDRG1,EZR,LEPR,NFIB,KLHL2,PHYHIP,ADD3,GATA2,WFS1,BCL6,DAPK1,ERAP1,KLF5,NR4A2,MDFIC,MAP3K5,MOXD1,CITED2,RTN3,CBX7,MAFF |
| 3.689e-06 | -12.51 | negative regulation of kinase activity | biological process | GO:0033673 | 221 | 59 | 16441 | 2455 |
CASP3,SPRED1,NF2,CDKN1C,IBTK,UBASH3B,DNAJC3,PKN1,TRIB2,GSTP1,DUSP5,TP73,TFAP4,CDKN2C,RB1,IGF1R,PTEN,BMP7,RGS3,FBXO7,PAK2,DUSP10,H2AFY,CDKN1B,SORL1,DAB2IP,HEXIM2,CDKN2D,SPRY2,SOCS5,CHP1,DUSP1,PLK1,SIRT1,AKT1,COX11,PRKAR2B,EPHA1,ILK,DUSP4,MAPK8IP1,SOCS3,IRS2,CDK5RAP1,PTPRJ,PRKAG2,CAMK2N2,PPP2R5A,PRDX3,CORO1C,STK38,WWTR1,RGS14,UBE2C,HSPB1,HIPK3,PKIA,DRD1,PRKAR1A |
| 3.693e-06 | -12.51 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP | 191 | 52 | 17758 | 2588 |
GRN,FBLIM1,ALDH6A1,ST14,HLA-E,FAM129B,RASA2,CTDSPL,PPFIBP2,IL18,CAMK1D,PLA2G16,DNER,FAM101B,FLT3,FAM46C,IL18R1,LTBP3,ICAM1,DNAJB9,CCND1,DDHD2,FAM102A,TSPAN1,PTPRE,SPRY2,TMBIM1,S100A6,LGALS8,S100A4,PLAUR,MGAT4B,ARFRP1,PCTP,STK17B,SPAG1,FRMD4B,NAAA,TSC1,NFKBIA,FAM114A1,BMP1,PRDM5,ITGAV,GEM,AKNA,RBM43,CD81,GAB1,ABCA1,CPPED1,KLF7 |
| 3.693e-06 | -12.51 | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN | 191 | 52 | 17758 | 2588 |
SPRED1,CDK17,NFKBIE,FRMD6,CALB2,SOD2,OSGIN2,KCTD12,GDF15,CCNL1,PDGFB,PHLDA1,STIL,TNFSF9,DUSP5,NFAT5,ICAM1,BMP2,CYR61,FLRT3,BCL6,RAB20,SLAIN2,CITED2,TIPARP,C9orf72,DUSP1,GFPT1,TGIF1,RIPK2,PLSCR1,COQ10B,PLAUR,USP18,RAPGEF2,PTGER4,FAM133B,PIM3,DUSP4,ZFAND5,RNF19B,FOS,CD83,BCL10,BTG1,FGD6,ITGAV,MAFF,KLF7,USP16,IRF1,EHD1 |
| 3.693e-06 | -12.51 | GSE29618_MONOCYTE_VS_MDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_UP | 191 | 52 | 17758 | 2588 |
LAMP1,IL15,CD63,HLA-F,CTSB,PNPLA2,SOD2,ASAH1,NOTCH2,FAM198B,GRK6,ARHGEF40,IER3,ARHGEF10L,GNS,CD46,APLP2,FRY,DRAM1,SORL1,CTSD,TIAM1,CKAP4,TUBA4A,CYP1B1,CPD,MPP1,S100A4,CDA,BNIP3L,PYGL,NPC2,BLVRA,RNF19B,CRISPLD2,IRS2,HLA-B,SERPINA1,HPSE,RCBTB2,SEMA4D,NFKBIA,ZDHHC7,CLMN,ADIPOR1,SPRY4,PDXK,LTA4H,SLC31A2,RTN3,ABCA1,KLF7 |
| 3.693e-06 | -12.51 | GSE13306_TREG_VS_TCONV_SPLEEN_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_UP | 191 | 52 | 17758 | 2588 |
PAPSS2,ZCCHC24,SERPINB9,SDC4,IRX4,BLCAP,BCL2L1,TP53I11,NUCB2,OAT,ADAMTSL4,ZNF385B,CYP26A1,GBX2,KIF5B,SIPA1L2,IL6ST,ZDHHC23,SGK1,WWP1,ACOX2,PIM1,CNOT6L,NTN1,ITM2C,IL10RB,MAST4,FAH,RIPK2,ASXL1,PTPN9,PCBP3,MPP1,VAMP3,DUSP4,PTGFRN,TCEAL8,MYOM1,SESN1,MAP1B,NFIX,ARHGAP35,DGKH,PTPRJ,KIAA0141,SPINT2,KIAA1804,PRDM5,PER3,SNX30,CD33,DRD1 |
| 3.724e-06 | -12.50 | Downstream signal transduction | REACTOME pathways | R-HSA-186763 | 322 | 79 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,STAT6,PSMD3,STAT1,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,BCAR1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 3.724e-06 | -12.50 | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP | 196 | 53 | 17758 | 2588 |
SLC25A24,ARAP3,DYRK3,DDIT4L,MORC4,ASAH1,FAM101B,BMP2K,IER3,CAPN2,FAM111A,OXCT1,IRAK1,SNX18,METTL7A,ARL1,PLCG2,FUT8,CD9,GYS1,STEAP3,EPB41L4B,EGLN3,F2R,PTPRE,TTPA,IL10RB,CKAP4,IGDCC4,P2RX4,SYPL1,ZWINT,PLSCR1,MGAT4B,PANK1,PYGL,RNF19B,MAP3K6,NFIX,SFXN1,MAPKAPK2,PRKAG2,IDE,FASTKD1,JAK1,CDCA7L,APPL2,RAB31,TLE1,LRRK1,CMPK2,SERPINB1,FAM134B |
| 3.749e-06 | -12.49 | REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | REGULATION_OF_TRANSFERASE_ACTIVITY | 157 | 45 | 17758 | 2588 |
CCNE2,SPRED1,TAOK2,CDKN1C,TRAF2,ERBB2,HERC5,PKN1,TRIB2,CARD10,PICK1,CCND1,CDKN2C,DIRAS3,RB1,IRAK1,PTEN,RGS3,PAK2,MAP3K9,SERINC2,CKS1B,MDFIC,HEXIM2,MAP3K7,CDKN2D,CCDC88A,CKS2,MDFI,SOD1,STRADB,PIF1,PKMYT1,CDC25C,MAP3K6,EGFR,CDK5R1,CDK5RAP1,RBL1,MADD,KIAA1804,MAP3K11,MAP3K5,CD81,HIPK3 |
| 3.774e-06 | -12.49 | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | 97 | 32 | 17758 | 2588 |
CCDC109B,EPAS1,MCTP2,FAM101B,MXD1,CDKN2C,OSBPL3,CAPG,PRC1,TNFRSF18,PIM1,CNGA1,CTTN,TIAM1,ALS2CL,NEB,SLC16A5,FAH,SOAT1,MMD,MBNL3,TANC1,ALCAM,CD83,FRMD4B,GPLD1,SWAP70,GPRC5B,TWSG1,SH3BGRL2,CD81,RRAGD |
| 3.817e-06 | -12.48 | Signaling by FGFR | REACTOME pathways | R-HSA-190236 | 317 | 78 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,CBL,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 3.848e-06 | -12.47 | ONKEN_UVEAL_MELANOMA_DN | MSigDB lists | ONKEN_UVEAL_MELANOMA_DN | 505 | 111 | 17758 | 2588 |
LAMP1,LZTFL1,SLC35D2,SORBS1,ST13,LMCD1,TGOLN2,ERP29,PHLDA1,CMTM6,EPM2A,CCND1,SS18,CTNNB1,DPYSL2,ARL1,TSPAN6,ATP13A3,DLG1,PIK3CA,KCNS3,PDE4D,ETHE1,TIPARP,HSPA2,CTDSP2,CTH,NEK4,GCA,DSTN,NFE2L1,DAG1,ARF4,GABARAPL1,OSBPL2,FYN,PEX5,DDOST,AGPAT2,RAB11FIP1,KLF5,SERPINB6,SERPINI1,KLF11,RPL22,LTA4H,PPP2R5D,CBX7,PRKAR1A,RRAGD,RMND5A,PLSCR4,ALDH6A1,PEX6,SERPINB9,SDC4,ETV5,SOX9,ASAH1,GSTP1,AIP,FZD6,NRP2,H1FX,SIRPA,HDAC9,M6PR,WWP2,SLC25A36,CTNNBIP1,SPP1,ADD3,KIAA0895,PDCD10,PTEN,TFAP2A,PRKCI,KANK2,CADPS2,ERBB3,SPRY2,CRTAP,GPR161,PDGFC,RHOA,PLSCR1,TESK1,SYBU,PIK3R1,FHL2,VAMP3,ZSCAN12,LRRC1,MEST,NFIB,ZDHHC3,NMT2,CD83,GLCE,GNAS,BTG1,SCARB2,TIMP3,PLOD2,PRCP,MATN2,FAM3C,CSGALNACT1,NR4A3,GLB1,SLC25A38 |
| 3.971e-06 | -12.44 | vesicle-mediated transport | biological process | GO:0016192 | 1179 | 231 | 16441 | 2455 |
DOC2A,LAMP1,EXPH5,ILDR1,ARFGEF1,TRAPPC8,TGOLN2,LGI3,ITPR2,SYTL4,SNX9,PDGFB,DNER,RIC1,PICK1,SH3KBP1,CALM2,SUSD2,NAPG,RAB15,AP1M2,CTNNB1,RABEP2,ELMO2,ARL1,DPYSL2,LMAN2L,STEAP2,PIK3CA,DNM2,SNX16,RAB20,RP2,PIK3CD,TINAGL1,CTTN,MARCH2,TFG,SCARA3,PACSIN1,S100A13,RASGRP1,TUBA4A,XKR8,LAMP2,VPS11,SOD1,KDELR3,EZR,ARFRP1,KIF13A,LOXL2,MCFD2,ADRBK2,RAB2B,ARF4,VCP,OPTN,TRIM9,ENPP1,PLCG1,TBC1D17,DNM1L,WIPI1,AREG,LIMK1,RAB11FIP1,ARF6,RTN3,TC2N,ANXA11,GRN,ARAP3,INPPL1,MRC2,GGA1,BVES,CALM3,RAB6A,NCKAP1,MERTK,FAM21C,CALR,DOPEY2,TIMP1,SNX18,RINL,GATA2,RIMS3,ICAM5,FCHO1,EXOC8,PRKCI,SORL1,CADPS2,PIKFYVE,SYTL3,C9orf72,PPP6R1,TMED2,RIMS2,SNX7,KDELR1,GCC2,KIF20A,MAPKAPK3,CALM1,FBXO8,CALCRL,SCRIB,EIF2AK1,CYFIP2,GOLT1A,STX3,MAPKAPK2,AP1AR,HTT,CSNK1G1,MFSD2A,ITPR1,SH3BP4,RAB31,DYSF,PLD1,ARPC2,PLIN3,HOOK1,NRBP1,SNX30,EHD1,GPR107,TRIP10,RALBP1,P2RX7,FTH1,BCL2L1,MICALL2,EMP2,TMPRSS4,BCAP31,ZFYVE9,SYTL2,SDF4,PDGFA,SRPX,PLCG2,LMAN1,RAB27B,SNX10,TBC1D10B,CHP1,MYO5B,SNX8,SEC23A,CLCN3,COG2,DMTN,VPS4B,KIF1C,SYP,ITPR3,SNX12,TAPBP,FYN,STX10,AXL,CORO1C,CHMP4B,RAB29,SYT13,ABCA1,COPG1,ARFGEF3,BIN1,ANXA3,SORT1,PACSIN2,HSP90B1,TRAPPC10,CD63,ATP9A,SH3D19,HABP4,LRP4,ARL4C,CTSZ,PLD2,LGALS3BP,VPS26A,ITGA2B,M6PR,CXCL16,ANK1,ADORA1,ADRBK1,CTSC,LLGL2,FAM160A2,CDK16,CD9,CPLX1,SYK,MYO5A,RAB3B,PIK3R1,VAMP3,PGBD1,COL7A1,RAB3IP,YES1,AKAP3,NEURL1B,FAM109A,BBS2,MAPK8IP1,SCRN2,RGPD5,LDLRAP1,SERPINA1,FGFR2,RAB11FIP2,SYT7,RIN3,NR4A3,ARFGAP3,ARRB1,ITGAV,CD81,TBC1D4,ESYT2,SNPH |
| 4.108e-06 | -12.40 | V$CEBP_Q3 | MSigDB lists | V$CEBP_Q3 | 242 | 62 | 17758 | 2588 |
PLA2G4A,NCKAP5,SPRED1,DYRK3,LRRFIP2,DDIT4L,THRA,ETV5,ERBB2,ZNF28,PLAC1,HMGN3,FAM91A1,PDGFB,TSPAN7,SLC25A35,SIRPA,CALR,FOXP2,SS18,PTEN,CYR61,ANKS1B,CDK16,CALD1,LMO4,RRBP1,BCL6,GYS1,NCAM1,PLCB2,MAP3K3,ZNF462,ADAMTS2,CD55,CITED4,MOSPD2,WNT10B,SYNE2,PLS1,RAB3IP,SPTLC2,PCTP,SNX12,RHOB,EDNRA,GPLD1,XKRX,DGKH,PITX2,LEMD2,ALDH5A1,TIMM8A,MAOA,SFMBT1,NFKBIZ,EFNA5,PER3,ARNT,TOB1,CBX4,JARID2 |
| 4.202e-06 | -12.38 | microtubule cytoskeleton organization | biological process | GO:0000226 | 355 | 85 | 16441 | 2455 |
GAS2L1,CFAP74,SPC25,AK7,NDC80,XIAP,CNTROB,KIF2C,ZMYND10,STIL,WEE1,SS18,LRRC6,CTNNB1,TACC2,KIF14,DLG1,PLK4,TUBG1,DNAAF3,CHP1,PLK1,SPEF2,CAMSAP3,CENPA,PSRC1,CAPN6,FIGNL1,FOPNL,UXT,VPS4B,EZR,NUSAP1,AURKB,CDK1,DAG1,NIN,MAP2,PLK2,PPP2R4,RGS14,SGOL1,PPP1R12A,KIF23,RACGAP1,GPSM2,SPDL1,SSX2IP,LMNA,CKAP5,RB1,LLGL2,CENPJ,TUBGCP6,TBCD,NEK2,PRC1,SLAIN2,SPRY2,TTLL1,DNAI1,SUN2,GCC2,RHOA,KIF20A,CFAP46,TACC1,ASPM,MYBL2,STMN3,BBS2,KIF11,RANBP9,SPAG1,MAP1B,DCTN6,HTT,AURKA,PKD2,PPP2R3C,CENPE,WDR62,NDE1,ESPL1,FBXW5 |
| 4.241e-06 | -12.37 | mouth | COSMIC cancer mutations | mouth | 9422 | 1475 | 17775 | 2585 |
HECA,IBTK,GRIK2,AK7,PNPLA2,RET,MCOLN3,TRAPPC8,BAIAP3,LACTB2,SNX9,CARD10,LTBP3,GRM5,CDKN2C,NAPG,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,TMEM37,TIAM1,IL10RB,TIPARP,MGAT5,DNAAF3,NEK4,FBXL16,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,LCP1,PIAS3,ENPP1,PLCG1,CARHSP1,MPRIP,ATP7B,CELF5,FAM114A1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,STARD13,ANXA11,NXT2,SCN5A,GGA1,ITGA6,MTL5,CCDC64B,FAM21C,TTYH3,RABGGTA,TFAP4,RAC2,FRY,MEGF8,RIMS3,FLRT3,FBXO7,FBXL14,MAP3K9,USP1,FAM84B,ALPK1,PANX2,MAPK7,ZMYM1,ULBP2,DGKG,NUP85,PPP6R1,PAQR7,HPS3,KIF20B,ELK1,NPHP3,GOLT1A,DPYSL4,SFXN5,GNA11,PLIN5,MAGED2,SLC4A4,ETS2,DGAT2,CLMN,OSCP1,TMEM173,ADAMTS16,DMPK,DOCK9,WDR63,TPRN,LFNG,GRK6,FAM91A1,MOCS1,REPS1,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,DLG3,ZNF365,ETV4,MYT1,TMCC2,MX1,SNX8,COL6A2,RIPK2,APOBEC3D,PFKFB2,PTPN9,SEPT6,HTATIP2,DNAJB14,XRCC6BP1,TANC1,ZNF618,TRIM7,EBF2,GIGYF1,NFIX,CCNB3,SHROOM3,CDK19,WFS1,CORO1C,AXL,PNPLA6,FAM149A,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,ESRP1,TRAF2,HABP4,OSGIN2,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,ZFX,SLC25A45,ITGB8,IGSF9,KNDC1,TMEM62,CST3,TUBGCP6,KLC3,IGFBP2,RAG1,CASD1,PARP9,PVRL4,ADAMTS2,DUSP23,PIK3R1,NUB1,CXorf57,AK4,PGBD1,RAB3IP,C4orf27,CNTNAP1,PROM1,LDLRAP1,PLOD2,SYT7,SSNA1,ITGAV,OSR1,CMPK2,ACOT7,SRSF9,PHC1,TLL2,ILDR1,TNK1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,TEX2,GALM,MGAT5B,ITPR2,SPTB,FANCI,TFAP2E,SUSD2,BTG3,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,P4HB,IL6ST,PAPSS1,SLC44A1,MITF,TMEM143,ABCA2,NTN4,PLK1,KRT80,MARK1,KCNIP3,CELSR2,CR2,CCBL2,CKAP2L,NKAIN1,KDM4D,TRIM9,TNS4,PLEKHG6,KCNMB4,ZNF367,ARRDC1,KLF11,TC2N,HS6ST3,PRSS8,RUNX2,USH1C,HJURP,SORBS3,NCKAP1,FBLN1,RSAD1,TNS3,RINL,FRAS1,ICAM5,TBCD,FCHO1,AHCY,PIM1,FAR2,WNT3A,NTN1,CKAP4,DPYSL5,PCDH1,PLEKHA6,RGMB,MGAT4B,SCRIB,PDK3,CDK5R1,PRX,NMT2,RASGRP2,COL13A1,KBTBD2,OTUD6B,PHLPP2,SLC2A6,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,RAD21,HOXB7,TP53,P2RX7,BAHD1,EMP2,STIL,TTC21B,WDR44,TACC2,LMO4,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,CTDSP2,SULF2,AKT1,PTGER4,C3orf33,DAG1,ATP13A2,PTGS2,TAPBP,ZNF628,IDE,ABHD12,RBL1,STK38,IRF7,ARHGAP4,ST3GAL1,BTBD6,CTDSP1,CMAS,PINK1,CDH22,CPEB4,SCD5,GNAL,MCTP2,HAL,CDCA8,ERCC6L,GDF15,PARM1,IL22RA1,NRP2,SH2D4A,CD109,C16orf74,CDK16,TFAP2A,GTF2F2,FAM63A,IL17RA,TRIM21,SGK1,HMGCL,SYK,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,MOSPD2,PRICKLE1,DPP9,MAML2,GGH,COL7A1,RNPEP,TXNDC11,USP6,CNOT2,DDAH1,SCG2,NEIL3,FGF18,E2F1,ICOSLG,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,FAM171B,LAMP1,LGR4,HSPG2,TMEM86B,TSC22D3,CUL1,PDGFRL,CAMK1D,SEPT4,VASH1,OAT,PJA2,PICK1,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,POLL,KCNS3,PIK3CA,HYLS1,METAP2,SGCE,SPATA18,ACVR1C,CDYL,SLC35C1,KIF13A,LDB2,POR,PPP2R4,LRIG1,MAPK13,NFKBIZ,F2RL1,SLC31A2,FGD1,SEMA6B,RECQL,MRC2,TBC1D1,AKAP17A,TXNDC9,APBA1,PDXDC1,PSIP1,SH3RF2,CALR,DOPEY2,RALGPS2,LYPD3,BHLHE41,VASN,AIM1,DAPK1,PRKG1,ADCK2,TPST1,CACNA1D,C8orf58,SYTL3,TRAK2,PIGC,SPATA20,GCC2,KCNJ12,ADCK3,LPGAT1,DCHS1,PYGL,WHSC1,NPC2,ATP8B3,ANTXR1,PDE11A,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,MATN2,FAM83D,MPP2,APPL2,ARAP1,SFMBT1,CABIN1,CDK18,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCF25,REPS2,GPR107,CAPN12,DLGAP5,ST14,CCDC110,DDIT4L,CERCAM,RALBP1,ATP2C2,FAM78A,BCL2L1,FLT3,DDR1,CYP39A1,ZFYVE9,EPS8L2,C11orf84,CCNA2,ACAP2,TRANK1,EPHB4,OSBPL7,SULT2B1,NAGA,ATG4D,DOCK4,COG2,FOXJ2,CLSTN1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,CBL,ITPR3,ASB13,ALCAM,FZD7,AMZ2,ACAD10,NGFRAP1,TRIOBP,FAM195A,SLC27A3,COBL,MAMDC2,PRKAR1A,DEPDC1,SLC41A1,EPS8,HERC5,PBX3,PLD2,DNAH3,COX7A2,HLA-A,WWP2,CKAP5,SLC25A36,RASSF8,E2F7,FUT8,DRAM1,ERBB3,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ALDH2,LONRF3,ZC3H11A,PAPD7,TCFL5,ZKSCAN2,DIAPH2,YES1,FOS,CDK5RAP1,ACADSB,DGCR2,SEC14L4,FGFR2,TBX18,RIN3,ABCB1,WDR62,WDR91,ESPL1,MELK,RGMA,UGT8,UBE2Q1,VARS2,PLAC1,COMMD5,ADPRHL1,EPCAM,ZFYVE16,SIPA1L2,HSF2,CASC4,CDKL5,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,CTTN,MYRIP,IL1RAP,NLRP4,CXXC5,ASXL1,LAP3,ITCH,USP18,RGAG1,MAN2A2,GPRC5B,MADD,TDRD7,SP6,GLA,RBM43,NR2C2,PCSK5,ARAP3,ZNF395,SERPINE2,PYROXD2,ETV5,FAM81A,ADAMTSL4,DUSP5,QSOX2,B3GALNT1,CES2,NOXA1,PFKL,OCRL,COL6A1,MTMR10,PRKCI,LIMCH1,BRAT1,NPTN,HLA-C,ZRANB1,ETV7,GAD1,SLC12A2,SNED1,ELK3,PODXL2,VWA1,PDE5A,KIAA1109,PRRC1,HEATR5A,PDIK1L,C3orf58,STEAP1,MFSD7,RHPN1,SOX13,UAP1,NXPH4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,SNX30,DRD1,CCNE2,LMO7,NCKAP5,LZTFL1,SORBS1,HDAC11,SOD2,PDIA5,COL18A1,OSR2,PHLDA1,EXT2,KCTD9,SAP130,ZNF687,CYP4F11,ZBTB49,DIXDC1,EPB41L4B,ETHE1,NFKB2,SEPHS1,SOAT1,RFK,PTPRU,C3orf52,BTBD19,GLO1,CD40,TMTC2,CASP4,ARHGAP35,HSF4,SPTBN5,ABCA1,KDELC2,FBLIM1,ARHGEF11,TSPAN15,ARHGEF7,SH3D19,SHPRH,COL4A5,SBF1,XPR1,ITGA2B,HDAC9,SYDE2,TMEM63A,KIF5B,TOP2A,CARD8,A4GALT,BMP7,RRBP1,ARVCF,KANK2,CLIP2,SLC35A1,RPGR,MYO5A,B3GALT6,PGM1,PHF20L1,DCAF6,RC3H2,TTC7A,FAM73B,LEPR,LEMD2,ENDOD1,CD8A,CASP7,TRIM69,FIBCD1,RAP2C,CSGALNACT1,DTX4,ARRB1,UACA,ZMIZ1,PLOD3,RAB3IL1,NGEF,DOC2A,ACACB,KLK10,TRIM24,ADD1,IL15RA,AASS,MRPS15,TRIM5,DNAJC3,CACNA2D2,SMARCAL1,DHX8,NRG2,LGI3,CNTROB,CA8,BARD1,KIF26A,PHF1,EPDR1,ZYX,WEE1,PSMD1,TGFBR3,RGS12,AP1M2,ARHGAP42,PQLC2,KIAA1107,DNAH6,PPP1R16A,RDH14,ALDH1A3,SEMA3G,PIK3CD,MANF,ERAP2,TUBA4A,NWD1,SPEF2,SMARCA2,SPRTN,MTRF1L,LOXL2,F12,MYOM1,COL12A1,SLC44A3,TRIM47,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,GAB1,E2F8,HOXC13,FAM169A,ALDH6A1,TMTC3,CYP2J2,SOX9,STRN4,SLC36A4,ZNRF3,MERTK,LMNA,RAVER2,DNPEP,WDFY1,CD22,PRICKLE4,ZIC5,NCAM1,C9orf72,EPHX1,UFD1L,KIF20A,STAT4,MYBL2,PLS1,SPTLC2,CYB5A,PTPRF,NCOA3,SCARB2,MTFMT,SEMA4D,HTT,SETD3,ITPR1,DYSF,AURKA,OSMR,MDH1,DRP2,NDE1,ZNF502,RPS6KA3,XDH,ARHGAP11A,MTM1,PAPSS2,GALNT12,FAM131C,ACTR8,RGS20,ETNK1,TESK2,IL13RA1,NUF2,PRSS22,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,UHRF1BP1L,CDS1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,SSH3,PLEKHO1,SYNE2,RAB38,TTC12,SLC9A6,SIPA1L1,PLEKHG1,PDXK,RGS14,GEN1,TTC8,GALK1,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,PDIA3,ANO9,PKN1,NUCB2,ETS1,SRPX2,ICAM1,PDIA4,NEO1,DTX3L,CAPN2,CXCL16,ANK1,SLC27A6,IRAK1,ANKS1B,FAM160A2,ARSG,CTSC,KCNK5,PLEKHF1,TMBIM6,MAPK11,AK3,NPTXR,TPCN1,CRTAP,HCN3,AMOTL2,NUDT8,FAM160A1,RAPGEF2,EIF5A2,GRIN1,PLEKHA7,EMP3,SNTB1,ABLIM2,DCAF10,GALNT3,BTG1,KIAA0141,ATXN7L3,ACVRL1,CCDC6,CENPE,FHL1,DCBLD1,FOXA1,CYBRD1,GNPDA1,FAM199X,PPM1J,CUL4B,SUDS3,FHDC1,MCCC1,HDAC6,PDGFB,SDC1,PCNA,LMAN2L,MKRN3,ELF5,DDHD2,RGS5,ANO4,TLN2,PXMP4,NEB,DDX59,ZNF462,PCGF5,CD55,MCTP1,HN1L,EZR,ESYT1,ANLN,PRKRA,IDH1,CLCN2,ZBTB7B,LHFPL2,VCP,IRX3,OPTN,DPYSL3,PLCH1,MFAP3L,TBC1D17,WIPI1,MAP2,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,POMT1,GLCCI1,FAM89A,PRKAA2,HLA-F,CNTNAP2,DOCK11,IL18R1,PGAP1,SSX2IP,RB1,DAZAP1,VASP,IGF1R,SPIN4,PLCB2,ALDH3A2,PSMA5,ABCC1,C9orf9,CHSY3,CYP26B1,WDR72,TESK1,PCBP3,SPATA13,EIF2AK1,ANKRD29,ZDHHC3,G2E3,EPN3,MAPKAPK2,DHDH,H1F0,MFSD2A,ITGA7,LTBP2,CTBP1,RNF146,AVPI1,NF2,XYLT1,DGKA,CCDC68,ZNF28,ERBB2,FAM198B,LPIN3,CYP26A1,SDF4,PER2,CDK14,RAD23A,SRPX,PLCG2,LHX6,SRR,GYS1,SCN2A,EGLN3,DVL2,GM2A,CTH,CPD,SIRT1,MBP,FIGNL1,DUOX1,DNAJC10,ATP1A1,C19orf66,PTK7,ADAMTS14,ZBTB6,C1orf43,AIFM3,ZNF701,NDST3,MAN2B2,GSDMD,COL9A3,PACSIN2,TM2D2,MACC1,RUSC2,GNE,CHAC2,DSE,CRABP2,SIRPA,SLC9A2,PPP2R3A,ABCD1,KLF9,FAIM,CAMK2G,TLE6,IGDCC4,DLGAP1,MLEC,NR3C1,AMFR,PPARA,TRIM35,CAPNS1,AKAP3,FNDC3A,BCAR1,MAPK8IP1,CD83,PRDX4,BANK1,FAT4,SERPINA1,TWSG1,NMI,TMC5,NETO2,PGRMC1,FAM117A,PKD2,UBE2C,TBC1D4,SAT2,DIS3L,SUN1,GAA,ACVR1,PPP4R4,FAM129B,ATP8A1,PPFIBP2,PLXNA1,FAM101B,SLC20A1,ELMOD2,CHST2,NCS1,SESN3,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,ATRNL1,IQCD,MTMR11,TFG,PACSIN1,SMYD5,LOC81691,KIFC2,PBK,HSPA12A,NBPF3,MGAM,TNS1,AURKB,GALNT7,MCFD2,CCNF,SPNS3,ULK2,ARHGEF26,AHRR,KDSR,SLC25A4,RBM47,PLK2,PTER,GNPTAB,NKD1,FAM110C,EIF4EBP2,UNC5B,TANC2,TRAF5,RTN3,LZTS1,DLAT,CDK17,INPPL1,MRPL44,HLA-E,CALB2,SLC25A27,KIF23,ISYNA1,NOTCH2,SLC1A3,KIAA1161,MECOM,PIK3AP1,SNX18,RUNDC3B,CTPS1,SORL1,CD70,PIKFYVE,CTSD,EEF1D,RIMS2,IGSF3,EPB41L5,PMPCB,QSOX1,FADS2,B3GNT7,MFI2,KIAA1841,TBC1D8B,AMER1,PTPRH,ANO6,PIP4K2C,FAM133B,PKM,KDM3A,FBXO10,GLT8D2,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,DCK,NAB2,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,PKD1L2,SLC2A4,ARMCX3,NLRX1,CAST,SUZ12,IQGAP1,RPS6KA1,EGR3,MNS1,GNB2,CYHR1,APLP2,ZNF75D,FAM46A,DOK4,FICD,TNPO2,CDKN1B,PHKA2,LGMN,NR2C1,GPX4,TBC1D10B,MYO5B,SEC23A,CAPN6,TEP1,SLC11A2,C15orf39,AKR1E2,SP4,ZNF469,PRDM11,NIN,OSBPL2,EPHA10,FYN,JAK1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,NR3C2,DENND5B,ANKRD13D,PCOLCE,SLC16A14,ATP9A,CCNJL,GPR180,CYB561,APOBEC3H,SIX4,LGALS3BP,C16orf59,FAM111A,OXCT1,PTEN,MGAT1,PRC1,SLC44A2,TAGLN2,CNOT6L,MAP3K7,GFI1,TRIM62,NCOA2,OSGIN1,SMC4,PCCB,RASGRF1,ARAP2,CASK,DENND1B,FURIN,PARP4,LRRC1,RGS9,MAMDC4,CTNS,AMMECR1,CSTF2,SERPINB5,PGM2L1,GRIN2D,ETAA1,ARSB,OCLN,USP16,JARID2,ESYT2,EXPH5,LTBP1,TMEM184B,CPT2,HEBP1,EPHX4,TAF6L,KIF2C,KREMEN1,TMC1,TSEN34,CHPF,ABCD4,ARHGEF10L,LRRC6,DLG1,CAPG,POF1B,ANKRD12,KIF22,RAB20,NFU1,MYH14,ARNT2,PTPRE,RASGRP1,OLFML2A,TDP1,ATL1,TRIM8,SYNE3,FOPNL,ROR1,PTGFRN,TCN2,SEC14L2,LRRC42,CXXC4,ARHGEF19,FASTKD1,UEVLD,IARS2,TRIM45,ADIPOR1,RAP1GAP,PSMC1,MIIP,PPP2R5D,GRN,LRRFIP2,PEX6,ASL,ATP6V1E2,SAMD9,PHLPP1,ZNF432,LRRN2,KCNN4,EBF4,FNIP1,FXYD5,KNTC1,RFX5,PARD3B,OXR1,GYLTL1B,HMG20B,FBXO8,EGFR,MUM1L1,GLCE,GNAS,FECH,BCAR3,TSC1,PAPD5,CDCA5,ALPK3,RHOBTB2,KIF12,PROM2,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,SLC2A8,PSME2,MORC4,TDRKH,ZMYND10,PATL2,MICALL2,LRRC45,SLC25A48,SS18,KCTD15,SETDB2,ZDHHC12,FRYL,SMO,STEAP3,HSPA2,SCYL3,FRS3,MAP3K3,TAF5,KREMEN2,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,OVOL1,CANT1,PLXND1,CYP2U1,AKNA,PPP2R2D,LIFR,CBX4,POC1B,FRMD6,LRP4,FAM134A,TRMT2B,POMGNT1,SNX13,MLPH,GALNS,KIAA0319,BRD7,CKS1B,IQGAP3,ADAM17,RAB3B,NR4A1,PHLDB3,ASPM,OGDHL,LRRC66,MAP1B,KLHL2,HLA-B,HNRNPH2,DHRS2,SOX8,GEM,L1CAM |
| 4.251e-06 | -12.37 | cellular response to endogenous stimulus | biological process | GO:0071495 | 1133 | 223 | 16441 | 2455 |
CCNC,UGT8,ACVR1,TRIM24,SSH1,NRG2,GATA3,F11R,PSME1,ITPR2,PDGFB,SPTB,CALM2,ZFYVE16,ZYX,PSMD1,TGFBR3,CTNNB1,CTGF,SHC3,ZCCHC12,PSMC2,KLF3,FOSB,PIK3CA,DNM2,AKR1B1,PPP1CA,PIK3CD,RASGRP1,THRB,SOD1,CASP9,EZR,AGO4,PRKAR2B,POR,RHEB,ENPP1,PLCG1,TBX1,NOD2,CAB39,HDAC1,EIF4EBP2,ADIPOR1,PSMC1,GAB1,NR2C2,RRAGD,PRKAA2,KLF2,RUNX2,RASA2,SOX9,PRKAA1,PSMD7,ATP6V1E2,CALM3,PHLPP1,DUSP5,CORO1B,BMP2,TFAP4,IGF1R,MEGF8,FLRT3,COL6A1,PRKCI,C10orf54,NCAM1,MAPK7,PSMA5,PAQR7,EPB41L5,RGMB,CALM1,STRADB,ELK1,KDM3A,PSMA4,EGFR,RASA1,GNAS,FECH,TSC1,NCOA3,FNTA,PRKAG2,INSR,PHLPP2,ITPR1,SH3BP4,RAB31,NR4A2,LTBP2,JAK3,COL16A1,RARG,DRD1,EHD1,GAS2L1,SPRED1,SORBS1,SLC2A4,THRA,SLC2A8,IQGAP1,PSME2,TP53,WDTC1,ERBB2,RASGRP3,EGR3,BCL2L1,PRKACA,GNB2,ZFYVE9,PDGFA,ATP6V0B,ACAP2,CDH1,CDKN1B,DAB2IP,GOT1,PDE4D,RASGEF1A,NR2C1,FRS3,BAG4,RIPK2,AKT1,DMTN,CBL,ITPR3,CASP4,SOCS3,IRS2,PTGS2,FYN,IDE,ATP1A1,JAK1,RBL1,PSMD3,WWTR1,STAT1,PPP1CB,SLC27A1,NRG1,SPTBN5,NR3C2,PRKAR1A,SORT1,HSP90B1,NKX3-1,TNRC6C,CPEB4,CTSB,SERPINB9,LRP4,GABRG2,PSMD10,TGFBR1,GDF15,FGF19,ICAM1,HDAC9,CAPN2,ADRBK1,PTEN,BMP7,FUT8,CD9,IGFBP2,KLF9,ERBB3,MAP3K7,SYK,SPRY2,CAMK2G,MYO5A,NCOA2,DUSP1,HCN3,P2RX4,PDGFC,TGIF1,RASGRF1,ADAM17,RHOA,SHMT1,PSMB4,WNT10B,NR3C1,RAPGEF2,NR4A1,PIK3R1,GRIN1,PPARA,FURIN,YES1,FOS,BCAR1,BBS2,GPLD1,CTSL,PLOD2,FGFR2,TWSG1,NR1D2,ACVRL1,FGF18,E2F1,NR4A3,GRIN2D,GPER1,ATP6V1C1,PLOD3,CD81,TBC1D4,CPEB2,RGMA |
| 4.263e-06 | -12.37 | HOXA9_DN.V1_UP | MSigDB lists | HOXA9_DN.V1_UP | 182 | 50 | 17758 | 2588 |
SLC35D2,ARHGEF3,CCDC109B,PARP12,ARL4C,IL13RA1,GDF15,VASH1,OAT,TSEN34,UHRF1BP1L,AKIRIN1,GNS,ZFYVE16,TYMP,ENTPD4,FRY,FDXR,SGK3,BAX,SORL1,ACTA2,TAX1BP3,MARCH2,PTPRE,SNX10,CYP1B1,OSTM1,COQ10B,RNF11,PTGER4,GALNT7,CYFIP2,FNDC3A,SESN1,FOS,TP53I3,CRISPLD2,FAS,FUCA1,FYN,RBM47,HPSE,RCBTB2,PLK2,NOD2,TDRD7,STK39,NDFIP1,TOB1 |
| 4.263e-06 | -12.37 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP | 182 | 50 | 17758 | 2588 |
SIGIRR,KLF2,HECA,TRAPPC10,TSC22D3,INPP5D,TMEM41B,EPHA4,TMX4,ARL4C,CCNL1,TRMT2B,TRIB2,FAM46C,DNAJB9,MARCH8,ADD3,ENTPD4,FAM46A,LLGL2,LYPD3,MGAT4A,FOSB,MTMR10,PIK3CA,SORL1,SGK1,CRY2,MYLIP,TIPARP,EEF1D,SMAGP,ATP2B1,DUSP1,SUN2,PIK3R1,PTGER4,FOS,RASGRP2,TXK,IRS2,CNOT2,BTG1,RAB11FIP2,PPP1CB,KLF11,NR3C2,TOB1,ATMIN,KLF7 |
| 4.298e-06 | -12.36 | PID_PLK1_PATHWAY | MSigDB lists | PID_PLK1_PATHWAY | 44 | 19 | 17758 | 2588 |
PLK1,RHOA,KIF20A,PPP1R12A,CDC20,NDC80,ERCC6L,CCNB1,BORA,CDC25C,CDK1,WEE1,PRC1,PPP1CB,TUBG1,AURKA,BUB1,CENPE,SGOL1 |
| 4.311e-06 | -12.35 | YAGI_AML_WITH_T_8_21_TRANSLOCATION | MSigDB lists | YAGI_AML_WITH_T_8_21_TRANSLOCATION | 358 | 84 | 17758 | 2588 |
SLC35D2,BCAM,UGP2,AGRN,RALBP1,RPS6KA1,CUL4B,CACNA2D2,IL27RA,TGOLN2,BCL2L1,DDR1,EXT2,ECI1,CDK14,RCN1,CDKN2C,CCND1,EPCAM,NOV,NUP210,RALB,STIM1,DPYSL2,CAPG,VAT1,MANF,ETHE1,CDKN2D,IL1RAP,ORAI2,S100A4,CLSTN1,GLO1,ABR,LCP1,NFIX,SOCS3,MDK,PLCG1,ALDH5A1,AGPAT2,JAK1,AREG,GDE1,SIPA1L1,HDAC1,PLXND1,CD99,SERPINE2,GNE,AES,TGFBR1,TSPAN7,TFAP4,CALR,SORL1,TMBIM6,RFX5,ABCC1,SOCS5,QSOX1,UFD1L,TGIF1,FBLN5,MAPKAPK3,PIK3R1,FURIN,AK4,ZSCAN12,BLVRA,MAGED2,GNAS,NT5C2,SWAP70,DGCR2,ACADSB,ITPR1,AURKA,FZD5,JAK3,CTBP1,ESPL1,CSRP2 |
| 4.311e-06 | -12.35 | KUMAR_TARGETS_OF_MLL_AF9_FUSION | MSigDB lists | KUMAR_TARGETS_OF_MLL_AF9_FUSION | 385 | 89 | 17758 | 2588 |
PLA2G4A,TXN,TTC39B,DNAJC3,GATA3,DDR1,EXT2,PLS3,CYHR1,RNF220,IMPAD1,CYP2S1,SMO,DAB2IP,IFIT1,F2R,SMAGP,LOC81691,CLCN3,CD55,CXXC5,AKT1,USP18,RNF11,CBX6,PTGER4,PRKCQ,ATP1B1,C15orf39,IDH1,NFIX,ANKRD10,FYN,MID1IP1,HOXA9,IARS2,PRDM5,IRF7,DLAT,OTUD5,SEMA6B,TM2D2,GOLIM4,CTSB,SDC4,CYB561,TNFRSF19,PSIP1,PDXDC1,LGALS3BP,B4GALNT1,M6PR,SPP1,RB1,RALGPS2,TAF1B,CTSC,CD9,ALDH7A1,TSPAN13,RAG1,CITED2,KANK3,SLC12A2,EPHX1,PCCB,PGM1,GUSB,SPATA13,TCF7,FAM73B,IFIT3,SPTLC2,TP53INP2,C18orf8,RHOB,CD83,GALNT3,RGS9,CD8A,H1F0,DCK,TMEM30A,RAB31,STK39,ATP1B3,CMPK2,RUSC1,DMPK |
| 4.317e-06 | -12.35 | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN | 187 | 51 | 17758 | 2588 |
CKAP2,DNAJC3,ITGA6,BLVRB,NENF,ISOC2,PLA2G16,B4GALT4,NUCB2,SDC1,ARHGEF16,LMNA,GBX2,PDIA4,TP73,RCN1,TYMP,TIMP1,MGAT1,P4HB,FICD,BHLHE41,RRBP1,CST3,HSPA13,ERCC2,TFG,CITED2,ITM2C,CKAP4,KDELR1,FAH,LAMP2,PCCB,TIMP2,PODXL2,RAPGEF2,COL7A1,OPTN,MDK,TRAM2,SLC25A4,UAP1,WIPI1,PLA2G15,ARFGAP3,PDXK,B4GALT3,RTN3,IFI6,MAPK12 |
| 4.317e-06 | -12.35 | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | MSigDB lists | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | 187 | 51 | 17758 | 2588 |
ARHGAP11A,SLC35D2,FARP1,ENO2,NQO1,GNPDA1,GMPR,PBX3,ASAH1,CYB561,NUCB2,SNX9,SYTL2,APOBEC3B,CDKN2C,EPCAM,WEE1,NPNT,KIF13B,FUT8,MTMR10,SNX16,CD70,HLA-C,LGMN,RPGR,TMBIM1,DUSP1,LOC81691,RFK,LPGAT1,BTBD19,STMN3,YES1,OPTN,HLF,PTPRJ,UEVLD,PHLPP2,CELF5,RAB31,RYK,APPL2,ABCB1,CAB39,FZD5,TTC39C,ARSB,TC2N,CSRP2,EHD1 |
| 4.317e-06 | -12.35 | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP | 187 | 51 | 17758 | 2588 |
ANXA3,TNRC6C,KIAA1462,UPF3B,ADD1,SCOC,SERPINE2,EPAS1,GALNT12,SERPINB9,ARMC7,TMX4,PBX3,TRMT2B,PHLDA1,EXT2,BMP2K,HLA-A,FZD6,PLS3,MAGOHB,SESN3,ELMO2,RALB,SLC16A6,IMPAD1,OCRL,TRIM21,TNFRSF12A,TECR,MYLIP,CASD1,RPGR,FGFR1OP2,RBMS2,EBAG9,CORO2A,RHOB,DNAJC10,SCARB2,UAP1,AGPAT2,AREG,H1F0,SH2D3C,PEX2,C1orf21,HS3ST3B1,RNASEL,ARSB,TMEM14A |
| 4.357e-06 | -12.34 | GSE15767_MED_VS_SCS_MAC_LN_UP | MSigDB lists | GSE15767_MED_VS_SCS_MAC_LN_UP | 192 | 52 | 17758 | 2588 |
MAN2B2,UNC93B1,REPS2,PYROXD2,LRP4,EPHA4,KIF23,SELL,ASAH1,PHOSPHO1,F11R,NOTCH2,DSE,NUCB2,APBA1,TMPRSS4,NRP2,TMCC3,CDS1,ATP6V0B,B3GALNT1,FAM46A,RALB,TSPAN6,FNIP1,STEAP3,IL10RB,SUSD3,PVRL4,KRT80,DOCK4,PDGFC,ALDH2,IFITM3,DSTN,HSPA12A,TEP1,NPC2,RAB38,FOS,TCN2,ATP13A2,BFSP1,RBM47,SMTNL2,ACVRL1,DBI,RAB31,CTNND1,NCAPG2,ABCA1,GAB1 |
| 4.383e-06 | -12.34 | HALLMARK_G2M_CHECKPOINT | MSigDB lists | HALLMARK_G2M_CHECKPOINT | 197 | 53 | 17758 | 2588 |
PTTG1,NDC80,KIF23,CUL1,RACGAP1,KIF2C,NOTCH2,BARD1,STIL,LBR,CCND1,TOP2A,KIF5B,CDKN2C,SS18,CCNA2,PRC1,NEK2,PLK4,CKS1B,CDKN1B,TNPO2,KIF22,BUB1,SLC12A2,SMC4,CKS2,HMMR,PLK1,CENPA,PAPD7,PBK,CDC20,MYBL2,WHSC1,KIF20B,NUSAP1,AURKB,CCNF,H2AFV,KIF11,CDK1,RBL1,E2F1,AURKA,EFNA5,KPNA2,HMGA1,CENPE,UBE2C,CCNB2,ESPL1,RAD21 |
| 4.432e-06 | -12.33 | protein disulfide isomerase activity | molecular function | GO:0003756 | 23 | 13 | 16491 | 2452 |
QSOX1,P4HB,ERO1A,TMX4,PDIA5,PDIA3,ERP44,PDIA6,TXNDC11,ERP29,QSOX2,TMX1,PDIA4 |
| 4.432e-06 | -12.33 | intramolecular oxidoreductase activity, transposing S-S bonds | molecular function | GO:0016864 | 23 | 13 | 16491 | 2452 |
QSOX1,P4HB,ERO1A,TMX4,PDIA5,PDIA3,ERP44,PDIA6,TXNDC11,ERP29,QSOX2,TMX1,PDIA4 |
| 4.440e-06 | -12.32 | LIM_MAMMARY_STEM_CELL_UP | MSigDB lists | LIM_MAMMARY_STEM_CELL_UP | 462 | 103 | 17758 | 2588 |
MYL9,SPRED1,SORBS1,SSH1,HSPG2,EPAS1,IRX4,COL18A1,EGR3,CACNB4,FAM101B,CARD10,EPDR1,ASPHD2,PLS3,PDGFA,TGFBR3,CTGF,SRPX,IL6ST,TRPC1,CDH3,TINAGL1,TMEM64,PTPRE,KCNIP3,SNTB2,RNF165,TNS1,COL12A1,DPYSL3,DZIP1L,PGF,TRIM9,TNS4,PTGS2,SLC25A4,AXL,MYLK,BMP1,NRG1,ZC3H12B,DMWD,SLC27A3,LIFR,MAMDC2,PCOLCE,GOLIM4,IGFBP6,BVES,RUSC2,ITGA6,LRP4,ETV5,SLC1A3,ZNF219,FBLN1,ETS1,EFNB1,NRP2,ICAM1,SLC27A6,CALD1,GPC3,BMP7,FJX1,TPST1,ACTA2,CD70,IGFBP2,C10orf54,SGCB,CHSY3,ADAMTS2,LCA5,ELK3,CTNNAL1,TACC1,DCHS1,GYLTL1B,PRICKLE1,COL7A1,MEST,BCAR1,ANTXR1,C3orf58,EGFR,PRX,FAS,ARHGAP24,TIMP3,RND3,ISM1,MATN2,SLC4A3,NETO2,PCDH19,PKD2,FHL1,GEM,OSR1,COL16A1,CSRP2 |
| 4.496e-06 | -12.31 | macromolecule localization | biological process | GO:0033036 | 2012 | 369 | 16441 | 2455 |
SUN1,LAMP1,ACACB,HSPG2,GRIK2,PNPLA2,ATP8A1,HEXB,TAP1,GATA3,TRAPPC8,SYTL4,SNX9,PICK1,NAPG,AP1M2,OSBPL3,DNM2,SNX16,PACSIN1,CPE,LAMP2,VPS11,ACVR1C,KDELR3,KIF13A,AURKB,ICMT,MCFD2,RNF19B,SPNS3,RAB2B,ARF4,ENPP1,DNM1L,GNPTAB,NOD2,ARF6,F2RL1,NXT2,NFKBIE,GGA1,SEC61G,SOX9,RAB23,APBA1,FAM21C,LMNA,ATG4A,MESDC2,CALR,DOPEY2,SNX18,RPL39,NECAB3,FBXO7,SORL1,CADPS2,PIKFYVE,SYTL3,NUP85,TSPAN33,TMED2,RIMS2,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,KIF20A,ANO6,CALCRL,KIF20B,NPC2,SRSF5,ATP8B3,PCTP,GOLT1A,RHOB,PLIN5,STX3,AP1AR,SCARB2,PRKAG2,TIMM8A,HTT,ZDHHC20,FAM83D,DGAT2,AURKA,HOOK1,NUP58,EHD1,PLA2G4A,MTM1,ARMCX3,THRA,APOO,C5orf30,PKP2,MVB12B,ZFYVE9,APPBP2,ACAP2,CDH1,TNPO2,IFIT1,ACSL4,OSBPL7,ARL4D,DLG3,RAB27B,FLOT2,SNX10,ATG4D,MYO5B,SNX8,SEC23A,SEC61B,COG2,FZD4,DMTN,SYNE2,VPS4B,SLC11A2,ATP1B1,PYGO1,RAB38,SNX12,ATP10D,OSBPL2,PEX5,STX10,DDOST,SHROOM3,CORO1C,SLC27A1,RAB29,TTC8,MZT1,HSP90B1,TAOK2,ATP9A,FLOT1,BTN3A1,PDIA3,ANO9,SPDL1,IFT27,TSPAN17,SIX4,PDIA4,CKAP5,ANK1,SLC27A6,RNF128,PPP1R10,FAM160A2,BAX,ATP8B1,PLEKHF1,NCOA2,LCA5,ZC3H11A,DENND1B,RAPGEF2,PIK3R1,EIF5A2,VAMP3,RAB3IP,NEURL1B,CPTP,CNTNAP1,RGPD5,LDLRAP1,MAMDC4,RPL12,RAB11FIP2,ARFGAP3,SSNA1,NUP37,CD81,WDR45B,SRSF9,ESYT2,EXPH5,UNC93B1,LTBP1,UGT8,FAF2,AGRN,CPT2,ARFGEF1,UBE2Q1,F11R,MPP5,HDAC6,NUP62CL,ERP29,ZFYVE16,MAGOHB,RAB15,NUP210,RABEP2,CTNNB1,NPNT,LMAN2L,ARL1,ABCA2,DLG1,SUN3,RAB20,RP2,CTTN,ANO4,TLN2,TRAM1,MYRIP,S100A13,PLK1,KCNIP3,CENPA,SYNE3,EZR,ARFRP1,ESYT1,CDK1,VCP,OPTN,TNS4,TRAM2,TBC1D17,UEVLD,WIPI1,RAB11FIP1,KPNA2,APBA2,PCSK5,RRAGD,PRKAA2,PEX6,ETV5,ATP6V1E2,NCKAP1,CNTNAP2,RAB6A,PGAP1,B4GALNT1,CORO1B,RB1,RINL,FRAS1,KIF13B,KCNN4,EXOC8,PRKCI,SRP54,WNT3A,SNX7,MDFI,KDELR1,BTN3A2,STRADB,SCRIB,NUBP1,ZDHHC3,EGFR,GNAS,TSC1,TMEM30A,MFSD2A,NFKBIA,SH3BP4,RAB31,ZDHHC7,CTSA,PITPNA,LTBP2,ATP1B3,SHROOM2,CDAN1,JAK3,TOB1,APOL2,SNX30,RAD21,DRD1,UPF3B,ABCG4,TP53,P2RX7,EMP2,STIL,BCAP31,SYTL2,TTC21B,ATP6V0B,SVBP,KIF14,ZDHHC12,FABP6,REEP1,BCL6,ZDHHC23,SMO,STEAP3,RPN2,LMAN1,F2R,GM2A,DVL2,UPF3A,CHP1,SOAT1,BAG4,AKT1,PTPRU,AP5M1,ERBB2IP,DAG1,PEX2,CHMP4B,RPL22,ABCA1,CNEP1R1,COPG1,PINK1,PACSIN2,CD63,TSPAN15,FRMD6,LRP4,PSMD10,AIP,VPS26A,SLC9A2,ZDHHC21,KIF5B,SNX13,ADORA1,MLPH,BMP7,RRBP1,TRIM3,H2AFY,CPLX1,ABCD1,SYK,RPGR,CAMK2G,MYO5A,SUN2,HES1,RAB3B,FBLN5,CRB3,PPARA,PRICKLE1,AKAP3,BBS2,SCG2,ARRB1,PKD2,SPCS3,ATP6V1C1,PLOD3,CEP41,RAB3IL1,ABCG1 |
| 4.588e-06 | -12.29 | establishment of localization | biological process | GO:0051234 | 3816 | 657 | 16441 | 2455 |
DOC2A,ACACB,ADD1,IBTK,GRIK2,SLC25A13,MCOLN3,CACNA2D2,TRAPPC8,TGOLN2,LGI3,BAIAP3,SYTL4,SNX9,SLC35E4,TP73,CALM2,NAPG,PQLC2,AP1M2,SLC46A1,ATP13A3,DNM2,TINAGL1,PIK3CD,TMEM37,TUBA4A,VPS11,UXT,KDELR3,PRKAR2B,LOXL2,ICMT,RNF19B,ARF4,SLC44A3,ENPP1,PLCG1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,RNASEL,ARF6,ANXA11,NXT2,SCN5A,NFKBIE,GGA1,SEC61G,RAB23,SLC36A4,GPSM2,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,ATP5H,RIMS3,FBXO7,RANBP1,PCYOX1,CADPS2,PANX2,CNGA1,NUP85,C9orf72,PPP6R1,NAGPA,UFD1L,SLC37A1,KIF20A,MAPKAPK3,ERO1A,CALCRL,PLS1,SRSF5,PCTP,GOLT1A,SFXN5,RHOB,CYB5A,CACHD1,SCARB2,SLC4A4,TIMM8A,HTT,ITPR1,DYSF,OSCP1,NDE1,ARPC2,TRPC3,NUP58,XDH,MTM1,CCDC109B,APOO,C5orf30,PKP2,MVB12B,PRKACA,APPBP2,CCND1,SCNN1A,CDH1,ACSL4,ARL4D,RAB27B,SNX10,TMEM9,SCN3A,SNX8,SEC61B,PSRC1,FZD4,SYNE2,VPS4B,HTATIP2,SYP,NUSAP1,RAB38,SNX12,PEX5,STX10,CORO1C,SLC9A6,AXL,PRIMA1,RGS14,SLC25A30,TTC8,TCAF1,TAOK2,HSP90B1,HABP4,FLOT1,BTN3A1,PDIA3,CTSZ,ANO9,KCNC4,IFT27,SLC25A43,TSPAN17,PDIA4,CXCL16,SLC25A45,ANK1,PDCD10,ADD3,SLC27A6,CTSC,FAM160A2,KCNK5,BAX,KLC3,WWP1,TPCN1,S100A6,HCN3,ACBD5,MOB4,LCA5,MFSD2B,PIK3R1,EIF5A2,MRS2,GRIN1,PGBD1,RAB3IP,FAM109A,NEURL1B,RGPD5,LDLRAP1,RPL12,RAB11FIP2,SYT7,SLC35B3,DBI,NR4A3,ARFGAP3,SSNA1,ITGAV,CENPE,NUP37,CD81,USF2,SRSF9,CYBRD1,UNC93B1,ILDR1,ARFGEF1,NDC80,F11R,ITPR2,HDAC6,PDGFB,NUP62CL,SUSD2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,ARL1,LMAN2L,SLC44A1,ABCA2,ANO4,SCARA3,TRAM1,S100A13,PLK1,KCNIP3,CELSR2,STAU2,EZR,ARFRP1,ESYT1,CLCN2,VCP,OPTN,TRIM9,TRAM2,TBC1D17,KCNMB4,WIPI1,RAB11FIP1,KPNA2,PIEZO1,TC2N,PRKAA2,FXYD3,SLC22A31,RACGAP1,RAB6A,NCKAP1,ANO1,PGAP1,SSX2IP,RB1,TIMP1,RINL,GATA2,FRAS1,ICAM5,KIF13B,FCHO1,SLC30A6,EXOC8,SELK,NTN1,ABCC1,STRADB,SCRIB,EIF2AK1,ZDHHC3,NMT2,MAPKAPK2,PVRL2,MFSD2A,SLC2A6,ZDHHC7,LTBP2,ATP1B3,PLD1,NIPA1,KCNAB3,UPF3B,TP53,P2RX7,SLC7A2,EMP2,BCAP31,SYTL2,SDF4,TTC21B,PDGFA,ATP6V0B,SRPX,PLCG2,BCL6,ZDHHC23,SCN2A,LMAN1,GM2A,PPIF,CLCN3,AKT1,ACO1,DAG1,ATP13A2,TAPBP,ATP1A1,MAOA,CHMP4B,SYT13,RPL22,COPG1,ARFGEF3,BIN1,PINK1,MFSD14B,PACSIN2,GOLIM4,TRAPPC10,CD63,CDCA8,GABRG2,CRABP2,AIP,VPS26A,SLC9A2,M6PR,ZDHHC21,CDK16,SLC35B4,SGK1,ABCD1,CPLX1,SYK,SLC45A3,CAMK2G,ATP2B1,P2RX4,HES1,FBLN5,PPARA,PRICKLE1,COL7A1,AKAP3,BBS2,MAPK8IP1,SCRN2,SERPINA1,SCG2,TMC5,PKD2,SPCS3,NDFIP1,TBC1D4,ARHGEF9,LAMP1,SLC35D2,TSC22D3,ATP8A1,KLC2,TAP1,GATA3,CCNB1,SLC20A1,RIC1,NCS1,SLC9A7,PICK1,CTGF,STIM1,ELMO2,OSBPL3,STEAP2,PIK3CA,SERINC2,KCNS3,SNX16,MARCH2,PACSIN1,TFG,XKR8,LAMP2,ORAI2,BNIP3L,SLC35C1,KIF13A,SLC17A5,MCFD2,SLC25A5,SPNS3,RAB2B,SFXN1,SLC25A4,AREG,GNPTAB,SARAF,F2RL1,SLC31A2,RTN3,MRC2,INPPL1,SLC25A27,NDUFA4,SLC1A3,APBA1,CALR,DOPEY2,SNX18,NECAB3,SLC16A6,RPL39,SORL1,CACNA1D,PIKFYVE,SYTL3,RIMS2,TMED2,TSPAN33,TRAK2,KCNJ12,GCC2,PMPCB,MFI2,CALM1,ANO6,NPC2,ATP8B3,CYFIP2,STX3,GABRD,AP1AR,SLCO4A1,PRKAG2,CSNK1G1,WDR19,ZDHHC20,SLC4A3,FAM83D,PLIN3,HOOK1,NRBP1,EHD1,PKD1L2,PLA2G4A,MFSD3,KIF3C,SLC2A4,GPR107,DLGAP5,TRIP10,RALBP1,ATP2C2,FTH1,CD274,BCL2L1,DDR1,TMPRSS4,SLC25A35,ZFYVE9,CNNM4,TNPO2,CDKN1B,IFIT1,OSBPL7,FLOT2,TBC1D10B,ATG4D,MYO5B,SLC5A11,SEC23A,COG2,DMTN,COX11,KIF1C,SLC11A2,ATP1B1,ITPR3,ATP10D,OSBPL2,FYN,DDOST,SLC27A1,RAB29,PRKAR1A,DENND5B,SLC16A14,SLC41A1,ATP9A,ARL4C,PLD2,CYB561,SPDL1,LGALS3BP,COX7A2,CKAP5,SLC25A36,PPP1R10,CD9,SGK3,ATP8B1,SLC44A2,TTPA,SPRY2,SLC16A5,NCOA2,CASK,ZWINT,ZC3H11A,DENND1B,FURIN,VAMP3,PARP4,YES1,CPTP,GPLD1,CRTC2,MAMDC4,CTNS,SEC14L4,FGFR2,SLC25A40,RIN3,ABCB1,GRIN2D,ARSB,SLC25A38,ESPL1,ESYT2,EXPH5,FAF2,TMEM184B,CRYM,CPT2,UBE2Q1,MPP5,KIF2C,CACNB4,DNER,SLC8B1,ERP29,TMC1,SH3KBP1,ABCD4,MAGOHB,ZFYVE16,RAB15,DPYSL2,DLG1,TRPC1,KIF22,RAB20,RP2,CTTN,SLC39A10,MYRIP,RASGRP1,SOD1,CENPA,SYNE3,ACBD3,ADRBK2,TCN2,EDNRA,SEC14L2,UEVLD,KCNK1,APBA2,PCSK5,GRN,LASP1,ARAP3,BVES,PEX6,ABCG2,ATP6V1E2,CALM3,CA2,KCNN4,PRKCI,FXYD5,SRP54,SLC12A2,GAD1,SNX7,KDELR1,FBXO8,BTN3A2,STEAP1,MFSD7,EGFR,GNAS,TSC1,SLC6A6,TMEM30A,NFKBIA,CDCA5,SH3BP4,RAB31,CTSA,PITPNA,SHROOM2,JAK3,TOB1,APOL2,SNX30,DRD1,DYNLRB1,SLC25A24,SORBS1,SLC2A8,ABCG4,MICALL2,SLC25A48,SVBP,KIF14,ZDHHC12,FABP6,REEP1,STEAP3,RPN2,F2R,UPF3A,CHP1,SOAT1,SLC39A8,OSTM1,AP5M1,ALDH5A1,PEX2,SPTBN5,ABCA1,ANXA3,SORT1,TSPAN15,SH3D19,LRP4,RBP7,ITGA2B,HMGXB4,TMEM63A,KIF5B,SNX13,MLPH,ADRBK1,ADORA1,LLGL2,RRBP1,ZDHHC13,TRIM3,H2AFY,SLC35A1,RPGR,MYO5A,SYPL1,SUN2,RAB3B,MAP1B,SLC18B1,ARRB1,MCUR1,GEM,ATP6V1C1,CEP41,RAB3IL1,ABCG1,SNPH |
| 4.676e-06 | -12.27 | negative regulation of intracellular signal transduction | biological process | GO:1902532 | 393 | 92 | 16441 | 2455 |
SPRED1,TNK1,NF2,NLRX1,FOXM1,SOD2,P2RX7,NDRG2,BCL2L1,EPM2A,TP73,NOV,DACT1,RGS3,TSPAN6,BCL6,DLG1,DUSP10,DAB2IP,TWIST1,CDKN2D,CHP1,SIRT1,PPIF,TIMP2,TNIP1,AKT1,FIGNL1,ITCH,PBK,EZR,TNFAIP8L1,ERBB2IP,DUSP4,C3orf33,DAG1,OPTN,ARHGAP35,PTPRJ,WFS1,STK38,STAT1,PRKCDBP,TLE1,SPRY4,RGS14,HSPB1,F2RL1,PRKAA2,PINK1,ARAP3,SERPINE2,NUAK1,RASA2,PRKAA1,PSMD10,PHLPP1,FBLN1,GSTP1,DUSP5,MECOM,CARD8,ITGA3,IGF1R,PTEN,BMP7,FNIP1,SORL1,TMBIM6,MAPK7,SPRY2,DUSP1,RHOA,PLAUR,LITAF,STMN3,CARD19,RANBP9,MAPK8IP1,G2E3,RASA1,LEMD2,ARHGAP24,TSC1,BANK1,ITPR1,NFKBIA,SH3BP4,ARRB1,GPER1,HIPK3,XDH |
| 4.742e-06 | -12.26 | MITSIADES_RESPONSE_TO_APLIDIN_DN | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_DN | 243 | 62 | 17758 | 2588 |
NF2,ENO2,ZNF395,DLGAP5,HJURP,FOXM1,CKAP2,IQGAP1,ATP8A1,MAN1A2,PTTG1,ERCC6L,CDCA8,CALM3,KCTD12,RACGAP1,TEX2,NOTCH2,CCNB1,LBR,FANCI,HDAC9,CALM2,TOP2A,WEE1,ADD3,CCNA2,NUP210,KIF14,FUT8,ATP13A3,FAM20B,NEK2,CD9,MSH2,BUB1,AHCY,SYK,MSH6,GPR161,ZWINT,CENPA,MMD,HN1L,ASPM,DENND1B,CALM1,MYBL2,WHSC1,NUSAP1,POLD3,DCP2,ANKRD10,DDAH1,TRAM2,ALDH5A1,AGBL5,AURKA,PDXK,NCAPG2,CBX5,MELK |
| 4.753e-06 | -12.26 | chordate embryonic development | biological process | GO:0043009 | 595 | 129 | 16441 | 2455 |
EMX1,ACVR1,ADD1,HSPG2,EPAS1,GATA3,PLAC1,CCNB1,PDGFB,CTNNB1,DLG1,ARNT2,ZBTB18,SPEF2,TFAP2C,ICMT,ZFAND5,GINS4,EDNRA,HS6ST1,PLCG1,TBX1,HOXA9,TRAF3IP1,TANC2,APBA2,E2F8,GAB1,MAFF,PCSK5,GRN,KLF2,RUNX2,CDKN1C,RAB23,NCKAP1,APBA1,ELF3,MECOM,BMP2,VASP,CYR61,GATA2,MEGF8,OCRL,MSH2,NEK2,WNT3A,TMED2,MDFI,EPB41L5,SALL4,DCHS1,VEZT,SCRIB,KIF20B,G2E3,EGFR,GNAS,TSC1,NCOA3,HTT,CCNB2,RARG,EGLN1,HOXB7,GRHL2,LFNG,ST14,TP53,WDTC1,BCL2L1,OSR2,STIL,PRKACA,RCN1,LMO4,PLK4,SMO,TWIST1,ECE1,DVL2,SULF2,AKT1,SOCS3,ARHGAP35,SHROOM3,PTK7,ARNT,COBL,CTHRC1,NKX3-1,CCM2,SDC4,TGFBR1,JAG2,HOXB2,PPP2R3A,FZD6,SIX4,GBX2,CAPN2,E2F7,MGAT1,BMP7,FUT8,TFAP2A,ERCC2,MAP3K7,TTPA,HES1,TGIF1,UBE2A,PRICKLE1,BCL10,CNOT2,ACVRL1,FGFR2,SPINT2,TBX18,PKD2,ZMIZ1,SOX8,OSR1,FZD5,PLOD3,SHOX2,NCAPG2,FOXA1 |
| 4.784e-06 | -12.25 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | 168 | 47 | 17758 | 2588 |
DDX58,PLA2G4A,ARHGEF3,PARP12,CDKN1C,PARP14,GMPR,PBX3,HERC5,SAMD9,HERC6,NFAT5,LGALS3BP,BMP2K,MECOM,DTX3L,CYP1A1,ITGB8,SLC27A6,FRAS1,IFIT1,OAS3,SCN2A,RAB27B,PARP9,MX1,ERMAP,PRSS23,USP18,KIF13A,ATP1B1,IFIT3,TXK,IRX3,TRIM9,PTGS2,C19orf66,HOXA9,FGF18,STAT1,INPP4B,KLF5,IRF7,CMPK2,IFIH1,IFI6,AHR |
| 4.813e-06 | -12.24 | human chrXq24 | chromosome location | human chrXq24 | 48 | 17 | 26250 | 2805 |
LAMP2,LONRF3,UPF3B,SEPT6,UBE2A,C1GALT1C1,NKRF,IL13RA1,RNF113A,DOCK11,SLC25A43,SOWAHD,SLC25A5,ZCCHC12,WDR44,RPL39,NKAPP1 |
| 4.905e-06 | -12.23 | GNF2_CKS1B | MSigDB lists | GNF2_CKS1B | 37 | 17 | 17758 | 2588 |
KIF20A,ASPM,CDC20,NDC80,CDCA8,KIF2C,AURKB,KIF11,CCNA2,RANBP1,CKS1B,BUB1,RNASEH2A,CENPE,UBE2C,ESPL1,MELK |
| 4.926e-06 | -12.22 | PUJANA_BRCA2_PCC_NETWORK | MSigDB lists | PUJANA_BRCA2_PCC_NETWORK | 408 | 93 | 17758 | 2588 |
CCNE2,SPC25,TRIM24,DLGAP5,IL15,FOXM1,SUZ12,PTTG1,NDC80,GATA3,KIF2C,CCNB1,BARD1,STIL,FANCI,CDKN2C,PCNA,HSF2,CCNA2,CNTRL,KIF14,SIVA1,PLK4,KIF22,RNASEH2A,MYBL1,NR2C1,SEPHS1,CKS2,CENPA,ASXL1,AGPS,SEPT6,STAU2,CDC20,COX11,PRKCQ,ARHGDIB,AURKB,CCNF,H2AFV,CDC25C,CDK1,PRIM1,ACYP1,XRCC3,RECQL,ARHGEF7,KIF23,LBR,PSIP1,HMGXB4,SAC3D1,CKAP5,TOP2A,RB1,TBCD,PAK2,BAX,MSH2,H2AFY,BUB1,USP1,KNTC1,PIKFYVE,RAG1,MPHOSPH9,SMC4,ABCC1,HMMR,PCCB,DDB2,ZWINT,ZNF84,MYBL2,KCTD20,WHSC1,KIF20B,TCF7,POLD3,KIF11,DCP2,DDX23,RCBTB2,E2F1,AURKA,CENPE,UBE2C,CCNB2,ESPL1,CTBP1,MELK,RAD21 |
| 4.928e-06 | -12.22 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | 130 | 39 | 17758 | 2588 |
HSP90B1,AGRN,CTSB,SDC4,COL18A1,CTSZ,GSTP1,LGALS3BP,LMNA,CALR,SPP1,DNPEP,CDH1,P4HB,CST3,CAPG,CD9,AKR1B1,ACTA2,GOT1,TINAGL1,CTSD,PSMA5,QSOX1,RHOA,TIMP2,PSMB4,LAP3,CLSTN1,GLO1,NPC2,PSMA4,VCP,FUCA1,NUCB1,FAM3C,CANT1,SERPINB6,CD81 |
| 4.978e-06 | -12.21 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN | 178 | 49 | 17758 | 2588 |
DDX58,SEMA6B,CCDC109B,DYRK3,IL15,TMEM217,PARP14,TRIM5,TRAF2,TAP1,UBE2Z,HERC5,GPR180,SAMD9,CD274,OSR2,HERC6,DUSP5,PRRG4,TMCC3,DTX3L,OTUD1,ZNF687,FAM46A,ZNRF2,OAS3,ETV7,APOBEC3G,LAMP3,AMOTL2,PCGF5,ARAP2,PLSCR1,PAPD7,IFIT3,PRX,FAS,GALNT3,PI4K2B,C19orf66,SECTM1,NLRC5,IRF7,CMPK2,IFIH1,SLC31A2,RARG,CSRP2,IRF1 |
| 5.016e-06 | -12.20 | RHO GTPases activate PAKs | REACTOME pathways | R-HSA-5627123 | 23 | 13 | 8202 | 1235 |
MYL9,CALM2,PPP1R12A,NF2,LIMK1,PAK2,CALM1,MYLK,PPP1CB,CALM3,MYH14,CTTN,MYL12B |
| 5.034e-06 | -12.20 | MICROTUBULE_CYTOSKELETON | MSigDB lists | MICROTUBULE_CYTOSKELETON | 149 | 43 | 17758 | 2588 |
KIF3C,DLGAP5,KLC2,KIF23,KIF2C,CNTROB,HDAC6,APPBP2,SAC3D1,CKAP5,ATG4A,TOP2A,KIF5B,CNTRL,TUBGCP6,TBCD,PRC1,ABCA2,NEK2,TUBG1,BUB1,KNTC1,CLIP2,ATG4D,PLK1,PCGF5,MARK1,UXT,CDC20,KIF20B,KIF11,CDK1,RANBP9,MAP1B,NIN,MAP2,MAP3K11,AURKA,PKD2,CEP41,NDE1,CCNB2,ESPL1 |
| 5.046e-06 | -12.20 | LEF1_UP.V1_UP | MSigDB lists | LEF1_UP.V1_UP | 183 | 50 | 17758 | 2588 |
PRKAA2,MYL9,WASF3,COL9A3,SCN5A,PAX6,IGFBP6,GNAL,GATA3,NES,KCTD12,EGR3,ISYNA1,CRABP2,S100A2,HOXB2,ANO1,CHST2,SCML1,PDGFA,KCNN4,BMP7,COL6A1,FJX1,PLEKHF1,LOXL1,APOBEC3G,CTH,KCNJ12,ELK3,NR3C1,S100A4,PLEKHO1,CDA,EMP3,RUNX3,MAP1B,DHRS2,PELI2,AXL,MAOA,PRKCDBP,LTBP2,FHL1,ARHGAP4,EPB41L4A,L1CAM,CYBRD1,RRAGD,PCSK5 |
| 5.097e-06 | -12.19 | GSE360_CTRL_VS_T_GONDII_DC_DN | MSigDB lists | GSE360_CTRL_VS_T_GONDII_DC_DN | 188 | 51 | 17758 | 2588 |
AGRN,IL15RA,MPZL1,TRIP10,PSME2,TAP1,SOD2,IL13RA1,EXT2,DUSP5,NRP2,FANCI,B4GALNT1,DIRAS3,BTG3,CCNA2,GNB5,PAIP2B,FICD,TAGLN2,NFKB2,LAMP3,DUSP1,POU6F1,CASK,IFITM3,RAPGEF2,SAT1,PTGER4,BNIP3L,AK4,GGH,AURKB,DUSP4,IFIT3,SNTB1,CYB5A,CD83,SOCS3,BTG1,SEMA4D,MATN2,NFKBIA,NR4A3,KLF11,ST3GAL1,TRAF5,IFI6,COL16A1,KLF7,DRD1 |
| 5.111e-06 | -12.18 | GNF2_FEN1 | MSigDB lists | GNF2_FEN1 | 56 | 22 | 17758 | 2588 |
HMMR,PCCB,ZWINT,DLGAP5,FOXM1,NDC80,RACGAP1,NUSAP1,KIF11,CDK1,FANCI,TOP2A,CCNA2,PCNA,PRC1,PLK4,MSH2,CCNB2,E2F8,SMC4,METAP2,CKS2 |
| 5.115e-06 | -12.18 | CACTGTG,MIR-128A,MIR-128B | MSigDB lists | CACTGTG,MIR-128A,MIR-128B | 322 | 77 | 17758 | 2588 |
LTBP1,VANGL1,CTDSPL,WDTC1,PDIA5,UBE2Z,FAM78A,BAHD1,GNB2,SS18,WEE1,EFR3A,CABP1,PPME1,STEAP3,FAR1,CTDSP2,DVL2,STK35,CPD,SIRT1,SMARCA2,NRBF2,PTPN9,VPS4B,TMTC2,GTF2A2,PDHX,SP4,FAM177A1,PTER,PLK2,CORO1C,SH2D3C,RAB11FIP1,FAM195A,ZC3H12B,APBA2,NXT2,FRMD4A,ARHGEF11,DCAF7,STRN4,TGFBR1,PGAP1,XPR1,NEO1,CCDC92,MGAT1,RIMS3,NEK2,FAM84B,WNT3A,CITED2,GAD1,FAM134C,CCDC88A,TMX1,IGSF3,MDFI,PAPD7,MGAT4B,PIK3R1,FURIN,ZKSCAN2,FXR2,PELI3,DCP2,MOSPD3,RND3,CCDC6,CSF1,C1orf21,DCUN1D1,MPP2,SH3BGRL2,CBX5 |
| 5.131e-06 | -12.18 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN | 193 | 52 | 17758 | 2588 |
DLGAP5,HJURP,FOXM1,GNPDA1,CDCA3,SMARCAL1,KIF23,RACGAP1,EGR3,CCNB1,FANCI,CKAP5,TOP2A,CCNA2,BDH1,PLK4,TUBG1,H2AFY,CKS1B,GOT1,RNASEH2A,FAH,LAMP3,HMMR,PCCB,ZWINT,CENPA,SHMT1,HN1L,KIF20A,ASPM,CDC20,NUSAP1,AURKB,ICMT,POLD3,KIF11,FANCE,FUCA1,IL1R1,SLCO4A1,CORO1C,AURKA,CSTF2,GLB1,GLA,NCAPG2,CCNB2,UBE2C,ESPL1,MELK,ACOT7 |
| 5.148e-06 | -12.18 | HALLMARK_P53_PATHWAY | MSigDB lists | HALLMARK_P53_PATHWAY | 198 | 53 | 17758 | 2588 |
ST14,NDRG1,CD82,TAP1,DGKA,TP53,BLCAP,JAG2,SDC1,TNFSF9,MXD1,EPS8L2,IER3,BMP2,PDGFA,RB1,PCNA,IRAK1,KIF13B,FDXR,DRAM1,BAX,TAX1BP3,STEAP3,WWP1,CTSD,F2R,PTPRE,ZNF365,OSGIN1,GM2A,EPHX1,CDKN2AIP,DDB2,MAPKAPK3,ADCK3,S100A4,SAT1,SERTAD3,CYFIP2,RNF19B,SESN1,FOS,TCN2,CDK5R1,FAS,FUCA1,BTG1,PLK2,SERPINB5,CD81,TOB1,DEF6 |
| 5.151e-06 | -12.18 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | 853 | 171 | 17758 | 2588 |
CCNI,HECA,SSH1,TSC22D3,CUL4B,RET,TAP1,XIAP,IL18,F11R,MORF4L2,ITPR2,ISOC2,PIGL,MAP1LC3B,ASPHD2,TFAP2E,SIPA1L2,ENTPD4,METTL7A,STIM1,PIK3CA,TMEM143,DUSP10,SNX16,CTTN,PTPRE,DDX59,TRIM8,CD55,BNIP3L,NFE2L1,IDH1,RAB2B,PLCH1,CARHSP1,MID1IP1,PTER,RAB11FIP1,SERPINB6,MAFF,INPPL1,CDK17,ALDH6A1,HLA-E,HLA-F,ZCCHC24,ETV5,SLC36A4,B4GALT4,DUSP5,TTYH3,PSIP1,BMP2K,GNS,DAZAP1,WDFY1,SLC16A6,C10orf54,NCEH1,C9orf9,GFPT1,DDB2,IFIT3,NPHP3,FAS,NCOA3,HTT,ITPR1,STK39,NDE1,SERPINB1,CBX5,RNF146,SLC25A24,ARMCX3,NQO1,CAST,FTH1,TMEM170B,PHLDA1,MXD1,UHRF1BP1L,RCN1,SP100,LMO4,BCL6,PDE4D,OSBPL7,SCYL3,CTH,AGPS,FOXJ2,PTGER4,UTRN,CD40,MYL12A,DNAJC10,ZNF641,FYN,JAK1,CDK19,TRIOBP,ZBTB6,AKNA,ST3GAL1,CBX4,FAM134B,OTUD5,ANXA3,CPEB4,ARHGEF7,GNE,BLVRB,FLOT1,MIER3,TGFBR1,TRIB2,ETS1,NFAT5,HLA-A,H1FX,DNAJB9,SLC25A36,HDAC9,IRF2BPL,CCDC92,CAPN2,E2F7,CEP97,TMEM87B,GNB5,LLGL2,FAM63A,HMGCL,ZNF230,HSPA13,KLF9,SGCB,SYK,MYO5A,P2RX4,TGIF1,ARAP2,HMGN5,PLSCR1,NR3C1,DENND1B,RAPGEF2,RAB3IP,SNTB1,SKA1,BSDC1,KLHL2,CRTC2,BTG1,RCBTB2,NR1D2,SLC25A40,CCDC69,ERAP1,ARRB1,ARFGAP3,PPP2R3C,PKD2,ITGAV,TBC1D4,CPEB2,ARHGEF9,ESYT2,GOLGB1 |
| 5.193e-06 | -12.17 | positive regulation of cell death | biological process | GO:0010942 | 596 | 129 | 16441 | 2455 |
CASP3,AGRN,GRIK2,RET,SUDS3,CAMK1D,SEPT4,HDAC6,BARD1,TP73,RPS6KA2,CTNNB1,CTGF,SIVA1,ALDH1A3,DNM2,PPP1CA,TIAM1,CYP1B1,SOD1,ACVR1C,CASP9,BNIP3L,PRKRA,SAV1,STK17B,VCP,ABR,DNM1L,PPP2R4,MAP3K11,KLF11,FGD1,BMF,ITGA6,ADAMTSL4,BMP2,TFAP4,CYR61,PAK2,DAPK1,PRKCI,MAP3K9,FNIP1,TNFRSF12A,WNT3A,ANO6,SCRIB,BCL2L13,ELK1,RHOB,CDK5R1,FAS,STK17A,MAP3K5,RARG,XDH,DMPK,NQO1,INPP5D,TP53,P2RX7,COL18A1,BCL2L1,PHLDA1,AIFM2,BCAP31,ARHGEF16,SRPX,BCL6,CDKN1B,STEAP3,DAB2IP,EGLN3,F2R,SIRT1,PPIF,AKT1,RIPK2,SLC11A2,CD40,PTGS2,NGFRAP1,CDK19,ARHGAP4,BIN1,NKX3-1,PINK1,ARHGEF3,ARHGEF11,TRAF2,ARHGEF7,DAP,BIK,PDIA3,AES,TGFBR1,TOP2A,CARD8,PTEN,CTSC,MCF2L,BMP7,TFAP2A,BAX,PLEKHF1,BUB1,ITM2C,OSGIN1,DUSP1,RHOA,WNT10B,PLAUR,RAPGEF2,RGCC,GRIN1,TRIM35,GPLD1,BCL10,BTG1,CASP7,NR4A3,E2F1,ARRB1,GPER1,ARHGEF9,MELK,NGEF,ARHGEF4 |
| 5.292e-06 | -12.15 | LINDGREN_BLADDER_CANCER_CLUSTER_2B | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2B | 376 | 87 | 17758 | 2588 |
MYL9,TCF25,DNAJC3,TSC22D3,LMCD1,COL18A1,IL27RA,PDGFRL,SLC7A2,FAM46C,SH3KBP1,NOV,CTGF,SRPX,RALB,DPYSL2,RGS5,PIK3CD,TMTC1,TIMP2,COL6A2,TNS1,AURKB,ZFAND5,LCP1,EDNRA,SOCS3,FYN,HLF,MYLK,LRIG1,RCAN2,NFKBIZ,RELL1,RTN3,PRKAR1A,PCOLCE,RUNX2,NFKBIE,NUAK1,HLA-E,ARL4C,SELL,NES,TGFBR1,DUSP5,BMP2K,SIRPA,NRP2,DNAJB9,ICAM1,RAC2,CYR61,COL6A1,UBE2J1,TPST1,ACTA2,MAPK7,MOXD1,MYO5A,IGDCC4,AMOTL2,B3GNT2,ALDH2,IFITM3,TACC1,NR4A1,MPP1,PLAUR,STMN3,PRICKLE1,TTC7A,EMP3,RUNX3,TCF7,NEURL1B,CRISPLD2,PITX2,RND3,NFKBIA,SPAG7,FHL1,GEM,ARPC2,JAK3,COL16A1,CYBRD1 |
| 5.302e-06 | -12.15 | negative regulation of cellular component organization | biological process | GO:0051129 | 574 | 125 | 16441 | 2455 |
GAS2L1,LZTFL1,ADD1,THRA,PTTG1,EPHA4,ARFGEF1,TP53,BCL2L1,CCNB1,PATL2,HDAC6,APC2,SPTB,PHF1,PICK1,IER3,RPS6KA2,LMO4,KIF14,CAPG,DNM2,VAT1,DAB2IP,ESPN,TWIST1,TACSTD2,SEMA3G,PACSIN1,HSPA2,TMBIM1,SEMA3B,PLK1,PPIF,SIRT1,BAG4,AKT1,DMTN,CDC20,PTGER4,PIF1,AURKB,CCNF,SLC25A5,ULK2,DPYSL3,TRIM9,PEX5,MID1IP1,PPP2R5A,PLK2,CORO1C,TRAF3IP1,TRIOBP,STAT1,CHMP4B,SPTBN5,TMOD2,RAB29,ARF6,RAP1GAP,PRKAR1A,SEMA6B,PINK1,PACSIN2,LGALS3,CKAP2,CIT,DNAJB2,EPS8,LRP4,PSMD10,FAM21C,FBLN1,LMNA,CORO1B,CTNNBIP1,SPP1,ITGA3,PTEN,BMP7,VASN,CST3,TBCD,KIAA0319,NEK2,MSH2,H2AFY,SORL1,BUB1,MAP3K7,NTN1,WNT3A,GFI1,ITM2C,SPRY2,TRIM62,RHOA,MFI2,RAPGEF2,RGCC,KDM3A,NUBP1,CDK5R1,ARHGAP24,AP1AR,SWAP70,PLEKHH2,FGFR2,SEMA4D,ACVRL1,ARAP1,AURKA,EFNA1,HMGA1,SHROOM2,TBC1D4,SEMA3A,UBE2C,ESPL1,CTBP1,FOXA1,JARID2,NGEF,PROM2 |
| 5.421e-06 | -12.13 | DAP12 signaling | REACTOME pathways | R-HSA-2424491 | 325 | 79 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PDGFB,PRKACA,SPTB,CALM2,PDGFA,PSMD1,SHC3,PLCG2,PSMC2,PIK3CA,CDKN1B,DUSP10,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,JAK1,PPP2R5A,PSMD3,MAP3K11,NRG1,SPTBN5,PPP2R5D,PSMC1,GAB1,PRKAR1A,TNRC6C,RASA2,HLA-E,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,SYK,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,PSMA4,EGFR,RASA1,FGFR2,PHLPP2,FGF18,ITPR1,ARRB1,GRIN2D,JAK3 |
| 5.422e-06 | -12.13 | regulation of cell migration | biological process | GO:0030334 | 630 | 135 | 16441 | 2455 |
ACVR1,ATP8A1,RET,GATA3,PLXNA1,CAMK1D,VASH1,HDAC6,PDGFB,DAPK2,TNFRSF18,TACSTD2,SEMA3G,PIK3CD,CYP1B1,ACVR1C,ARHGDIB,ABR,DPYSL3,PLCG1,MYLK,FAM110C,NOD2,HSPB1,F2RL1,GAB1,MIIP,DDX58,SEMA6B,ARAP3,SERPINE2,LGALS3,SOX9,FBLN1,LMNA,CORO1B,BMP2,CALR,RAC2,ITGA3,TIMP1,IGF1R,CYR61,SORL1,NTN1,EPB41L5,ANO6,SPATA13,KIF20B,EPHA1,ILK,RHOB,EGFR,ONECUT1,INSR,SEMA4D,PLPP3,CSF1,EGFL7,PLD1,EFNA1,SEMA3A,DRD1,NF2,PKP2,COL18A1,CD274,EMP2,PDGFA,SVBP,NOV,SP100,KIF14,DAB2IP,PDE4D,EPB41L4B,F2R,SEMA3B,DOCK4,BAG4,AKT1,PTPRU,DMTN,SYNE2,PTGER4,DOCK5,DAG1,IRS2,PTGS2,PTPRJ,CORO1C,NRG1,PLXND1,ARHGAP4,TCAF1,ANXA3,ADGRG1,ARHGEF7,SDC4,SELL,CBLL1,PLD2,JAG2,ETS1,SRPX2,ITGA2B,NRP2,ICAM1,HDAC9,CXCL16,PDCD10,ADORA1,PTEN,SGK3,ADAM15,SGK1,CITED2,SUN2,RHOA,ADAM17,RAPGEF2,MPP1,PIK3R1,RGCC,FURIN,BCAR1,GPLD1,SWAP70,ACVRL1,PRCP,RAP2C,FGF18,GPER1,ITGAV,ARSB |
| 5.431e-06 | -12.12 | CERVERA_SDHB_TARGETS_1_UP | MSigDB lists | CERVERA_SDHB_TARGETS_1_UP | 112 | 35 | 17758 | 2588 |
KIF3C,SLC25A24,CCDC109B,UBASH3B,SCD5,IL18,KBTBD11,RBP7,EMP2,TNFRSF19,REEP1,RAB20,IGFBP2,PIK3CD,PACSIN1,SGCB,S100A6,KRT80,OLFML2A,PRSS23,SH3BGRL,FHL2,LOXL2,DUSP4,NEURL1B,ABLIM2,MAP1B,HPSE,TMEM54,NOD2,PGM2L1,FAM149A,TANC2,SHOX2,PCSK5 |
| 5.431e-06 | -12.12 | MODULE_397 | MSigDB lists | MODULE_397 | 112 | 35 | 17758 | 2588 |
ARHGAP11A,IGFBP6,HOXB7,FOXM1,TBC1D1,PTTG1,NDC80,KIF23,NUF2,GPSM2,ARHGEF16,SAC3D1,ZNF432,DNAH6,PLK4,ALDH7A1,EPHB4,DVL2,IGSF3,PLK1,CDC20,OGDHL,MBNL3,MYBL2,KIF11,CDCA7L,CDCA5,E2F1,AURKA,DONSON,CABIN1,CENPE,EFNA1,AFAP1,RUSC1 |
| 5.437e-06 | -12.12 | MICROTUBULE_BASED_PROCESS | MSigDB lists | MICROTUBULE_BASED_PROCESS | 81 | 28 | 17758 | 2588 |
SUN2,NF2,UXT,KIF23,NUSAP1,SORBS3,KIF2C,CNTROB,APBA1,KIF11,RASA1,CKAP5,ARHGEF10L,KIF5B,TSC1,MID1IP1,AP1M2,CENPJ,KIF13B,TUBGCP6,CAPG,PRC1,ARAP1,MAP3K11,TUBG1,KPNA2,ARF6,CCDC88A |
| 5.437e-06 | -12.12 | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | MSigDB lists | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | 81 | 28 | 17758 | 2588 |
SORT1,CELSR2,KIAA0040,GDF15,PRKAR2B,GALNT7,MDK,EPN3,MAGED2,PTPRF,SCNN1A,PROM1,MLPH,SERPINA1,TJP3,ACADSB,AREG,PLK2,WFS1,OPN3,RAB11FIP1,CADPS2,ANXA9,ERBB3,GRAMD1C,MAST4,HOOK1,ISOC1 |
| 5.489e-06 | -12.11 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | 103 | 33 | 17758 | 2588 |
CDKN1C,ATP9A,ZCCHC24,CYP39A1,PARM1,NEO1,SESN3,SNX18,GPC3,TNPO2,RGS5,TINAGL1,MYBL1,SLC12A2,SEMA3B,CPD,PIK3R1,RC3H2,ATP1B1,LOXL2,CBL,DPYSL4,NFIB,MAP1B,ENDOD1,FAT4,FGFR2,PTK7,PLEKHG1,CENPE,SLC27A3,FOXA1,PCSK5 |
| 5.519e-06 | -12.11 | cellular protein localization | biological process | GO:0034613 | 1143 | 224 | 16441 | 2455 |
SUN1,LAMP1,EXPH5,UNC93B1,FAF2,UGT8,AGRN,GRIK2,TAP1,TRAPPC8,F11R,MPP5,SYTL4,HDAC6,SNX9,ERP29,PICK1,ZFYVE16,NAPG,RAB15,AP1M2,CTNNB1,ARL1,DLG1,SNX16,SUN3,RAB20,CTTN,TLN2,PACSIN1,TRAM1,MYRIP,CPE,PLK1,VPS11,KCNIP3,CENPA,SYNE3,KDELR3,EZR,ARFRP1,KIF13A,AURKB,ICMT,CDK1,RAB2B,ARF4,VCP,OPTN,DNM1L,WIPI1,GNPTAB,KPNA2,ARF6,RRAGD,NFKBIE,GGA1,PEX6,SEC61G,SOX9,ETV5,RAB23,RAB6A,CNTNAP2,APBA1,PGAP1,LMNA,ATG4A,MESDC2,CORO1B,CALR,RB1,SNX18,RPL39,KIF13B,FBXO7,EXOC8,PRKCI,SRP54,SORL1,PIKFYVE,WNT3A,SYTL3,NUP85,TSPAN33,TMED2,RIMS2,MDFI,KDELR1,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,STRADB,KIF20B,NUBP1,ZDHHC3,RHOB,EGFR,STX3,AP1AR,SCARB2,TIMM8A,HTT,TMEM30A,ZDHHC20,NFKBIA,SH3BP4,RAB31,FAM83D,ZDHHC7,AURKA,CTSA,LTBP2,ATP1B3,JAK3,TOB1,DRD1,EHD1,RAD21,ARMCX3,THRA,TP53,PKP2,EMP2,STIL,BCAP31,ZFYVE9,APPBP2,SYTL2,TTC21B,ACAP2,CDH1,ZDHHC12,REEP1,BCL6,ZDHHC23,SMO,TNPO2,RPN2,IFIT1,LMAN1,RAB27B,DLG3,F2R,SNX10,FLOT2,DVL2,CHP1,ATG4D,SNX8,SEC23A,SEC61B,BAG4,AKT1,PTPRU,SYNE2,ATP1B1,RAB38,PYGO1,ATP10D,DAG1,PEX5,STX10,DDOST,PEX2,CHMP4B,RAB29,RPL22,CNEP1R1,COPG1,PINK1,PACSIN2,HSP90B1,TAOK2,MZT1,CD63,TSPAN15,FRMD6,LRP4,FLOT1,PDIA3,PSMD10,SPDL1,IFT27,TSPAN17,AIP,VPS26A,SIX4,ZDHHC21,SNX13,ANK1,ADORA1,MLPH,RNF128,PPP1R10,BMP7,BAX,PLEKHF1,H2AFY,SYK,RPGR,MYO5A,SUN2,HES1,RAB3B,FBLN5,CRB3,RAPGEF2,PIK3R1,VAMP3,PRICKLE1,RAB3IP,BBS2,CNTNAP1,RGPD5,RPL12,ARFGAP3,SSNA1,PKD2,SPCS3,CD81,WDR45B |
| 5.572e-06 | -12.10 | Signaling by ERBB2 | REACTOME pathways | R-HSA-1227986 | 320 | 78 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,ERBB2IP,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,YES1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 5.656e-06 | -12.08 | negative regulation of protein kinase activity | biological process | GO:0006469 | 204 | 55 | 16441 | 2455 |
CASP3,SPRED1,NF2,CDKN1C,IBTK,UBASH3B,DNAJC3,PKN1,TRIB2,GSTP1,DUSP5,TP73,TFAP4,CDKN2C,RB1,IGF1R,PTEN,BMP7,RGS3,FBXO7,PAK2,DUSP10,H2AFY,CDKN1B,SORL1,DAB2IP,HEXIM2,CDKN2D,SPRY2,SOCS5,CHP1,DUSP1,PLK1,SIRT1,AKT1,PRKAR2B,EPHA1,ILK,DUSP4,MAPK8IP1,SOCS3,CDK5RAP1,PTPRJ,PRKAG2,CAMK2N2,CORO1C,STK38,WWTR1,RGS14,UBE2C,HSPB1,HIPK3,PKIA,DRD1,PRKAR1A |
| 5.757e-06 | -12.07 | CHICAS_RB1_TARGETS_GROWING | MSigDB lists | CHICAS_RB1_TARGETS_GROWING | 229 | 59 | 17758 | 2588 |
CCNE2,ANXA3,PCOLCE,DEPDC1,FOXM1,CDCA8,CHAC2,FAM198B,CCNB1,FBLN1,PGAP1,PSIP1,ANO1,LMNA,TOP2A,APOBEC3B,CCNA2,RALGPS2,SPIN4,KIF14,AIM1,NEK2,MSH2,BUB1,USP1,RNASEH2A,IQGAP3,SCARA3,MSH6,SMC4,HMMR,ADAMTS2,CENPA,KIF20A,FIGNL1,ASPM,CDC20,EZR,PRICKLE1,STMN3,PYGL,WHSC1,NUSAP1,MEST,LDB2,DPYSL3,PRIM1,TRAM2,AXL,CDCA7L,NMI,MYLK,MATN2,C1orf21,LTBP2,NCAPG2,CCNB2,CBX5,NRGN |
| 5.775e-06 | -12.06 | PETROVA_PROX1_TARGETS_UP | MSigDB lists | PETROVA_PROX1_TARGETS_UP | 27 | 14 | 17758 | 2588 |
TOP2A,CCNE2,GPRC5B,CDKN1C,PDLIM3,NDC80,MYBL2,PYGL,BTBD3,UBE2C,CDK1,CSRP2,SMAGP,SMC4 |
| 5.857e-06 | -12.05 | SCIBETTA_KDM5B_TARGETS_DN | MSigDB lists | SCIBETTA_KDM5B_TARGETS_DN | 77 | 27 | 17758 | 2588 |
HMMR,GCA,SMARCA2,RECQL,DLGAP5,PBK,SOX9,CDCA3,NDC80,KIF2C,CCNB1,CDK1,PSIP1,LGALS3BP,CYB5A,PLS3,TOP2A,SS18,SWAP70,SCNN1A,FJX1,REEP1,AURKA,LIMCH1,IGFBP2,FHL1,TMEM14A |
| 5.872e-06 | -12.05 | Downstream signaling of activated FGFR2 | REACTOME pathways | R-HSA-5654696 | 310 | 76 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 5.872e-06 | -12.05 | Downstream signaling of activated FGFR3 | REACTOME pathways | R-HSA-5654708 | 310 | 76 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 5.872e-06 | -12.05 | Downstream signaling of activated FGFR4 | REACTOME pathways | R-HSA-5654716 | 310 | 76 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 5.872e-06 | -12.05 | Downstream signaling of activated FGFR1 | REACTOME pathways | R-HSA-5654687 | 310 | 76 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,PRKAR1A,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,ITPR1,FGF18,ARRB1,GRIN2D,JAK3 |
| 6.006e-06 | -12.02 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | 189 | 51 | 17758 | 2588 |
ANXA3,LTBP1,TMEM184B,ZCCHC24,ASL,ETNK1,COL4A5,PDGFRL,TXNDC9,MORF4L2,SRPX2,TEAD3,PDGFA,SS18,TGFBR3,RPS6KA2,IMPAD1,ATP13A3,RRBP1,TPST1,TWIST1,TNFRSF12A,MTMR11,MOXD1,ALDH3A2,OLFML2A,GFPT1,LAMP2,COL6A2,OSTM1,PIP4K2C,FHL2,MCFD2,ILK,NPDC1,GLT8D2,TP53I3,ATP10D,LEPR,CRISPLD2,EDNRA,SGPP1,STK17A,DNAJC10,SLC25A4,GPRC5B,KCNK1,FGD6,CTSA,PKD2,PLOD3 |
| 6.006e-06 | -12.02 | GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP | 189 | 51 | 17758 | 2588 |
CTHRC1,TMEM184B,SPC25,AGRN,GCAT,NDRG1,CDCA8,PLD2,NENF,BAIAP3,PATL2,SLC25A35,DAPK2,WDFY1,PQLC2,RPS6KA2,CDH1,GRHL1,PRICKLE3,KIF13B,OSBPL3,MITF,ENPP5,ABCA2,ALDH7A1,FARP2,HMMR,OPLAH,ASPM,STAU2,PCBP3,PANK1,CCBL2,IFIT3,PTGFRN,NPDC1,TCEAL8,STEAP1,FRMD4B,TBC1D17,COL13A1,PHLPP2,WFS1,C1orf21,ALG2,CMPK2,ARSB,CHPT1,CCNB2,UBE2C,RARG |
| 6.031e-06 | -12.02 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP | 194 | 52 | 17758 | 2588 |
PLA2G4A,HEBP1,FAM129B,TSC22D3,EPS8,MCOLN3,CYB561,FAM101B,FLT3,SNX9,IL18R1,SIRPA,ICAM1,PER2,TMEM63A,IER3,CCND1,SLC25A45,CA2,RGS3,MITF,PCYOX1,TMEM51,H2AFY,FAM102A,DAB2IP,HLA-C,TTPA,CASD1,IL10RB,TSPAN33,IGDCC4,SOCS5,SULF2,P2RX4,PIGC,GCLC,USP18,PYGL,IL1R1,NR1D2,PRCP,HOXA9,CDCA7L,APPL2,RAB31,ARRB1,LRRK1,GEM,CD81,ABCA1,CD33 |
| 6.124e-06 | -12.00 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | 538 | 116 | 17758 | 2588 |
TRIM2,UGT8,PNISR,CRYM,PSME2,ATP8A1,RALBP1,SLC25A13,ARFGEF1,TRAPPC8,MORF4L2,OAT,PJA2,BCAP31,CDK14,CDS1,PLS3,CD46,APLP2,WEE1,DPYSL2,IL6ST,PAPSS1,VAT1,GOT1,RGS5,ACSL4,MINPP1,F2R,BTBD3,CYP1B1,LAMP2,NEK4,SEC23A,RFK,SH3BGRL,ACBD3,DSTN,SEPT6,CBX6,PRKRA,H2AFV,IDH1,CASP4,ARF4,ZMPSTE24,TAPBP,FYN,DDOST,WWTR1,STAT1,MAOA,KPNA2,RPL22,ARF6,F2RL1,PRKAR1A,RECQL,LASP1,SERPINE2,PPP1R2,HLA-F,EPS8,PDIA3,HMGN3,GTF3A,TXNDC9,BMP2K,HLA-A,RB1,KIAA0895,ADD3,OXCT1,IGF1R,GPC3,CD9,PRKCI,ACTA2,WWP1,HSPA13,ERBB3,NPTN,CITED2,NCOA2,EEF1D,TMX1,SYPL1,PGM1,RHOA,PLSCR1,LPGAT1,LITAF,AK4,FBXO9,KIAA1109,FNDC3A,PSMA4,FRMD4B,PRDX4,FECH,NCOA3,FNTA,SWAP70,ACADSB,NR1D2,PLOD2,HNRNPH2,NMI,FAM3C,TCEAL4,RYK,MDH1,FHL1,TOB1,AHR,RPS6KA3 |
| 6.138e-06 | -12.00 | microtubule | cellular component | GO:0005874 | 391 | 90 | 17570 | 2579 |
GAS2L1,DYNLRB1,KIF3C,TUBB4B,NDRG1,IQGAP1,KLC2,XIAP,KIF2C,HDAC6,MAP1LC3B,KIF26A,APC2,APPBP2,CALM2,SS18,STIM1,DNAH6,KIF14,DPYSL2,DLG1,DNM2,TUBG1,KIF22,TUBA4A,PLK1,CAMSAP3,PSRC1,KIFC2,CAPN6,SNTB2,STAU2,KIF1C,KIF13A,NUSAP1,AURKB,CDK1,GABARAPL1,NIN,CEP162,MID1IP1,DNM1L,SHROOM3,MAP2,FAM110C,MAP3K11,RGS14,REEP4,CKAP2,CALM3,KIF23,RACGAP1,DNAH3,CKAP5,KIF5B,CENPJ,KIF13B,TBCD,TUBGCP6,PRC1,NEK2,KLC3,SLAIN2,KNTC1,CLIP2,TTLL1,SPRY2,MYO5A,DNAI1,C9orf9,TPGS2,KIF20A,ASPM,CALM1,SYBU,PARP4,KIF20B,SKA1,KIF11,MAP1B,BCL10,AURKA,CENPE,NDE1,CFAP20,KIF12,SHROOM2,HOOK1,RUSC1,SNPH |
| 6.142e-06 | -12.00 | LABBE_WNT3A_TARGETS_UP | MSigDB lists | LABBE_WNT3A_TARGETS_UP | 108 | 34 | 17758 | 2588 |
SERPINB9,RACGAP1,PDGFB,NFAT5,TSPAN7,CCND1,TOP2A,SPP1,PCNA,ADD3,CCNA2,CA2,CTGF,CYR61,CTSC,SIVA1,SGK1,NFKB2,CPE,AMOTL2,FADS2,IFIT3,ALCAM,CDK1,NMT2,PRIM1,GPLD1,GNAS,NGFRAP1,DCK,AURKA,KPNA2,CCNB2,AHR |
| 6.177e-06 | -11.99 | skin-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-head_neck-carcinoma-squamous_cell_carcinoma | 14911 | 2243 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,MCOLN3,CCNO,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,SEC61G,GGA1,ITGA6,MTL5,RAB23,GPSM2,FAM21C,TTYH3,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,TTLL1,MCCC2,FHL2,NPHP3,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,GDF11,TMEM173,DMPK,WDR63,KIAA1147,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,MRS2,NUB1,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,TLL2,BCAM,TNK1,KIAA1462,EPAS1,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,ABCA2,NTN4,SMAGP,MARK1,PTPN18,STAU2,CBX6,NFE2L1,CR2,ARFRP1,DZIP1L,TRIM9,PI4K2B,KCNMB4,ARRDC1,KLF11,PARP12,RUNX2,USH1C,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,XRCC3,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SGCE,SPATA18,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,CCDC97,FGD1,TBC1D1,TXNDC9,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,PANK1,UTRN,KIF1C,PKMYT1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,FGF19,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,RAB31,NXPH4,CTSA,AFAP1,RARG,SNX30,NCKAP5,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,ANKRD6,MYLK,AGFG2,LSM14B,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,DHX32,NCOA3,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,CCDC109B,ACTR8,RGS20,ETNK1,NUF2,PRSS22,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TNRC6C,TAOK2,RBM24,PARP14,MAN1A2,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,PLEKHB1,VCP,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,C1orf116,CYP26A1,ABRACL,CDK14,N4BP3,GYS1,FAR1,SIRT1,TMTC1,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,GNE,PSMD10,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,SMYD5,XKR8,TMEM68,SNTB2,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,ADO,DGKQ,CALB2,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,KDM3A,RASA1,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,PLA2G4A,TMEM217,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,SLC25A35,APLP2,FAM46A,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,MPP1,DENND1B,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,FLYWCH2,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,ZNF114,UEVLD,IARS2,RAP1GAP,PPP2R5D,CPPED1,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,KIF12,PROM2,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,MUC4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,CARHSP1,PLCG1,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,MEGF8,ATP5H,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PAQR7,HPS3,SHARPIN,KIF20B,SFXN5,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,RHBDL3,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,TMCC2,MX1,TMEM200B,COL6A2,PFKFB2,GIGYF1,EBF2,GABARAPL1,CCNB3,PNPLA6,DMWD,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,ZFX,SLC25A45,FUT2,ITGB8,KNDC1,TMEM62,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,UBE2A,AK4,LDLRAP1,PROM1,RPL12,PLOD2,PPM1H,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,TXNRD3NB,KPNA2,TTC39C,TC2N,RRAGD,HS6ST3,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,SCD5,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,IL22RA1,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,MOSPD2,GUSB,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,BCL10,USP6,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,PDXDC1,TSPAN7,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,WHSC1,ANTXR1,PDE11A,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,KIF3C,SPRED1,CAPN12,GPR107,REPS2,DLGAP5,TCTN2,ST14,RALBP1,CERCAM,NDRG1,THRA,CCDC110,BLCAP,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,AMZ2,DDOST,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,TRAPPC13,LAP3,USP18,ACBD3,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,NPTN,SLC12A2,CCDC88A,PODXL2,VWA1,HEATR5A,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,ECE1,ETHE1,SEPHS1,EBAG9,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,RBMS2,WNT10B,RUNX3,FAM73B,NDRG3,FOXL1,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,SPTLC2,PTPRF,SCARB2,DYSF,OSMR,SERPINB1,RPS6KA3,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,PSRC1,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,WWP1,NPTXR,AMOTL2,FMN1,FAM160A1,CTNNAL1,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,ZNF462,CD55,ING1,HN1L,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,EPB41L4A,GLCCI1,FAM89A,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,LTBP2,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,SLC7A2,CCNL1,LPIN3,SDF4,PER2,SRPX,EFR3A,PLCG2,LHX6,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,TP53I3,ULK2,AHRR,FAM177A1,SLC25A4,GNPTAB,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,AIFM2,MNS1,CNNM4,LGMN,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,CASP3,LTBP1,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,CCDC74B,ADIPOR1,LEMD1,APBA2,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,LRIF1,ALS2CL,OXR1,BTN3A2,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,PSME2,SLC2A8,GMPR,MORC4,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,BAG4,KREMEN2,SNAPC2,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,GCLC,DEPDC4,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,DHRS2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 6.277e-06 | -11.98 | KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP | 733 | 150 | 17758 | 2588 |
TMEM184B,GNPDA1,CRYM,BAIAP3,PLA2G16,CDIPT,OAT,SLC20A1,ERP29,MAP1LC3B,ECI1,CHPF,CALM2,PAK6,KIAA1107,DPYSL2,LMAN2L,CABP1,DDHD2,AKR1B1,ATRNL1,CRY2,ARNT2,PPP1CA,TECR,BTBD3,MYRIP,TUBA4A,SOD1,DSTN,RNF11,NFE2L1,CBX6,KLK6,ESYT1,MAN2A2,MSL1,SLC25A4,GPRC5B,KCNK1,MADD,PPP2R4,SERPINI1,ITPKA,APBA2,NRGN,PSMC1,LASP1,NUAK1,DHPS,DNAJB2,PSMD7,CALM3,NCKAP1,TSPAN7,CA2,RIMS3,SORL1,AHCY,GAD1,TMED2,NAGPA,FADS2,STAT4,CALM1,NPC2,CYFIP2,ILK,RASA1,GNAS,MAGED2,GABRD,UTP14C,SLC4A3,TCEAL4,SPAG7,MDH1,CTSA,CABIN1,ARPC2,SHROOM2,RUSC1,TUBB4B,NDRG1,BLCAP,EGR3,SNN,KBTBD11,BCAP31,CDK14,APLP2,ATP6V0B,EFR3A,REEP1,GOT1,LGMN,ZNF365,GPX4,DOCK4,AKT1,TCEB2,DRAP1,CLSTN1,SYP,GLO1,BCL7B,PDHX,PAFAH1B3,DDOST,PNPLA6,RCAN2,LTA4H,CBX7,COBL,BIN1,PINK1,ENO2,RUSC2,PSMD10,GTF3A,TRIB2,COX7A2,SAC3D1,SNTA1,CCDC92,IRAK1,MCF2L,CD9,FAM102A,H2AFY,NPTXR,SLC35A1,CAMK2G,ALDH2,RHOA,PSMB4,TCFL5,AMFR,FBXO9,CAPNS1,FXR2,NUCB1,SCG2,SPINT2,PPM1H,DTX4,PGRMC1,SSNA1,CD81,ACOT7 |
| 6.291e-06 | -11.98 | Interleukin-3, 5 and GM-CSF signaling | REACTOME pathways | R-HSA-512988 | 254 | 65 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,INPP5D,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,PRKACA,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,DUSP4,CBL,IRS2,FYN,JAK1,PPP2R5A,PSMD3,MAP3K11,NRG1,SPTBN5,PPP2R5D,PSMC1,INPPL1,RASA2,PSMD7,CALM3,PSMD10,TEC,FGF19,DUSP5,ITGA2B,ERBB3,NCAM1,SYK,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,YES1,PSMA4,RASA1,EGFR,FGFR2,FGF18,ARRB1,GRIN2D,JAK3 |
| 6.340e-06 | -11.97 | RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 34 | 16 | 17758 | 2588 |
MAP3K3,ACVR1,ACVR1C,MAPK4,TGFBR1,MAP3K6,IRAK1,ACVRL1,MAP3K9,MAP3K11,MAPK13,MAPK11,MAPK7,MAP3K5,MAP3K7,MAPK12 |
| 6.396e-06 | -11.96 | large_intestine-colon-carcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma | 2718 | 471 | 17775 | 2585 |
FAM171B,SUN1,HECA,ACACB,KLK10,LGR4,IL15RA,SSH1,HSPG2,FAM160B1,GRIK2,VANGL1,TMEM41B,ATP8A1,FAM129B,RET,CACNA2D2,PLXNA1,BARD1,FAM46C,NCS1,TP73,ZFP36,RGS3,OSBPL3,ATP13A3,AOX1,POLL,PIK3CA,TACSTD2,SEMA3G,WBP4,CPE,APOBEC3G,ERAP2,TUBA4A,NWD1,SMARCA2,KIFC2,SPATA18,HSPA12A,TMEM98,TMEM151A,TFAP2C,SLC17A5,CCNF,PNKD,COL12A1,LCP1,TRIM47,GNPTAB,LRIG1,TRAF3IP1,FAM110C,DHTKD1,SERPINB6,NFKBIZ,F2RL1,GAB1,LZTS1,CCDC97,FRMD4A,GGA1,TBC1D1,CYP2J2,ITGA6,SOX9,DGKQ,SLC1A3,APBA1,MERTK,TTYH3,LMNA,MESDC2,RAVER2,ELF3,TFAP4,CALR,FLII,DOPEY2,WDFY1,FRY,LYPD3,ZNRF2,SNX18,VASN,MAP3K9,SORL1,USP1,ALPK1,CACNA1D,PANX2,PIKFYVE,CTSD,MAPK7,KANK3,SYTL3,C9orf72,MCCC2,TSPAN33,GCC2,HPS3,KIAA1841,CEP89,B9D2,SALL4,AMER1,PTPRH,KCTD20,PLS1,KIF20B,SPTLC2,RASA1,PTPRF,PRKAG2,HTT,PELI2,ARAP1,FGD6,DYSF,PCDH19,CABIN1,OSCP1,KLK7,ZNF502,TRPC3,RPS6KA3,XDH,EHD1,PKD1L2,PLEKHG3,TPRN,KIF3C,TCF25,ARMCX3,DLGAP5,PAPSS2,ST14,THRA,DDIT4L,SUZ12,RNF182,PRSS22,FLT3,EPS8L2,APPBP2,UHRF1BP1L,ZNF75D,ST5,CDH1,CNNM4,DAB2IP,ACSL4,TSPAN1,FLOT2,RNF169,MYO5B,SEC23A,COL6A2,SYNE2,PANK1,UTRN,TEP1,TMEM144,PRKCQ,ATP1B1,C15orf39,CBL,XRCC6BP1,TANC1,ALCAM,FZD7,GABARAPL1,NIN,IRS2,FYN,ACAD10,TTC12,AXL,KIAA1804,ZNF704,PLEKHG1,PNPLA6,SLC27A1,KLF5,DMWD,MLKL,OTUD5,FARP1,MPZL1,SLC16A14,ATP9A,TRAF2,OSGIN2,CBLL1,HERC5,ANO9,GSTP1,KCNC4,DNAH3,NEO1,WWP2,CKAP5,PDIA4,FAM111A,ANK1,TMEM87B,ITGB8,PHF7,ARSG,KNDC1,TUBGCP6,FDXR,ATP8B1,MAPK11,ERBB3,RAG1,SGCB,TRIM62,MSH6,FARP2,HCN3,PDGFC,ARAP2,TCFL5,GRIN1,FURIN,FAM109A,FOS,TXK,CRTC2,CNTNAP1,GALNT3,NUCB1,SEC14L4,FGFR2,RAB11FIP2,RIN3,TBX18,ABCB1,ARFGAP3,CENPE,ITGAV,FHL1,OSR1,WDR62,WDR91,NCAPG2,CPEB2,ESPL1,ACOT7,DEF6,MELK,USP16,JARID2,EXPH5,BCAM,AGRN,PPM1J,CPT2,LMCD1,MCCC1,ITPR2,PDGFB,DENND2D,PLS3,ARHGEF10L,BTG3,SIPA1L2,NUP210,CTNNB1,LRRC6,CDKL5,ZCCHC12,DPYSL2,IL6ST,ANKFN1,ABCA2,CAPG,SUN3,ARNT2,TECR,SLC39A10,TLN2,CYP1B1,ZNF462,OLFML2A,KRT80,ATL1,MCTP1,MARK1,CELSR2,SYNE3,ASXL1,LAP3,CBX6,NFE2L1,C12orf65,ROR1,IDH1,PTGFRN,DZIP1L,KDM4D,MFAP3L,ZNF114,KLF12,MAP2,TTC39C,CHPT1,MIIP,CPPED1,RRAGD,PCSK5,BMF,ZNF395,CHCHD7,UBASH3B,PSMD7,ABCG2,ADCK5,CNTNAP2,FBLN1,IGF1R,PFKL,RINL,ICAM5,COL6A1,FXYD5,SRP54,FNIP1,AHCY,BRAT1,LIMCH1,RFX5,ZRANB1,CCDC88A,MDFI,ABCC1,WDR72,PCDH1,USP31,CORO2A,KIAA1109,SCRIB,RNF113A,C3orf58,MFSD7,NMT2,CDK5R1,GLCE,GNAS,BCAR3,ONECUT1,INSR,ITGA7,SLC2A6,NLRC5,SH3BP4,NXPH4,CTSA,AFAP1,CTBP1,RNF146,PROM2,RAD21,LMO7,PAX6,ZSWIM5,FOXM1,SLC2A8,XYLT1,TP53,IL27RA,MICALL2,LPIN3,STIL,PER2,SAP130,ZNF687,KHNYN,CYP4F11,KIF14,FRYL,N4BP3,PLCG2,LHX6,SMO,GYS1,NOTCH3,HSPA2,CTH,SEPHS1,SOAT1,MBP,RFK,OSTM1,ACO1,MRPS35,CDC25C,DAG1,MYPOP,PTPRJ,RBL1,ADAMTS14,PLXND1,ARHGAP4,LTA4H,ABCA1,PPP2R2D,DYRK3,GOLIM4,ARHGEF11,RUSC2,ARHGEF7,CTSB,FRMD6,LRP4,FAM167A,AIP,PPP2R3A,ITGA2B,M6PR,TMEM63A,ZDHHC21,KIF5B,CEP97,LLGL2,A4GALT,MAGEE1,SLC35B4,IL17RA,KANK2,ABCD1,BUB1,HEXIM2,KLF9,CLIP2,SYK,MYO5A,FAH,DLGAP1,SYPL1,WNT10B,NR4A1,PLAUR,ASPM,RC3H2,GGH,RUNX3,COL7A1,PELI3,FNDC3A,RNPEP,LEPR,MAP1B,USP6,SCRN2,CNOT2,FUCA1,SERPINA1,FAT4,C2orf70,TRIM69,UACA,GRAMD1C,ATP6V1C1,TBC1D4,L1CAM,AHR,ARHGEF4,GOLGB1 |
| 6.418e-06 | -11.96 | MODULE_11 | MSigDB lists | MODULE_11 | 516 | 112 | 17758 | 2588 |
TRIM2,PAX6,EPAS1,CRYM,THRA,EPHA4,TMX4,CACNA2D2,C5orf30,NRG2,BAIAP3,EGR3,PLA2G16,APC2,CARD10,CCND1,PHYHIP,SRPX,TACC2,CABP1,LMO4,BCL6,RGS5,ARNT2,IFIT1,BTBD3,CPE,HSPA2,TMCC2,SGCE,MBP,CBX6,KLK6,LDB2,ALCAM,PLEKHB1,FZD7,DPYSL3,TRIM9,HLF,GPRC5B,MAP2,KCNK1,MYLK,TLE1,MAOA,RCAN2,SERPINI1,ITPKA,APBA2,NRGN,ABCA1,BIN1,WASF3,COL9A3,ENO2,CDH22,ATP9A,DNAJB2,ITGA6,ETV5,SOX9,CALB2,GABRG2,CYB561,CNTNAP2,SLC1A3,SEPP1,TSPAN7,RND1,NEO1,SPP1,CA2,GNB5,NECAB3,RIMS3,SGK1,ALDH7A1,IGFBP2,HSPA13,ERBB3,NCAM1,GAD1,RIMS2,ATP2B1,IGSF3,EPHX1,FADS2,MMD,GCLC,BCL9,GRIN1,TCF7,FOS,DPYSL4,RHOB,TIMP3,SERPINA1,FGFR2,SCG2,ITGA7,ITPR1,NAB2,RAB31,TCEAL4,CDK18,STK39,L1CAM,CSRP2,PKIA,ARHGEF4,SNPH |
| 6.521e-06 | -11.94 | single-organism organelle organization | biological process | GO:1902589 | 2192 | 397 | 16441 | 2455 |
DOC2A,SUN1,CFAP74,SSH1,ADD1,AK7,MRPS15,XIAP,CCNO,TRAPPC8,SYTL4,MORF4L2,CNTROB,CCNB1,FAM101B,SNX9,CENPN,PAK6,WEE1,PHYHIP,ZYX,PIK3CA,TUBG1,PACSIN1,TFG,DNAAF3,NEK4,VPS11,SPEF2,SPATA18,DSTN,PBK,UXT,CDYL,BNIP3L,MTRF1L,SLC35C1,AURKB,LOXL2,PIF1,CCNF,MCFD2,MYOM1,ABR,LCP1,PRIM1,DNM1L,AREG,LIMK1,PLK2,TRAF3IP1,MYLK,PPP2R4,PRDM5,HDAC1,MRPS28,TMOD2,ITPKA,ARF6,FGD1,INPPL1,MRPL44,PRKAA1,RAB23,KIF23,SLC1A3,GPSM2,LMNA,ATG4A,CALR,FLII,RAC2,ZCCHC17,FRY,SNX18,RIMS3,FBXO7,FAM13B,NEK2,MSH2,PRKG1,SLAIN2,ALPK1,PPP6R1,TTLL1,SYTL3,TMED2,DNAI1,EPB41L5,REC8,GCC2,DDB2,KIF20A,B9D2,CEP89,MYBL2,WHSC1,PLS1,KIF20B,JADE2,KDM3A,ANTXR1,NCOA3,FAM64A,MTFMT,HTT,SETD3,TEX30,WDR19,FAM83D,ARAP1,FGD6,AURKA,DYSF,MDH1,NDE1,ARPC2,EHD1,ELK4,MTM1,TCTN2,DLGAP5,TMSB15A,TRIP10,LFNG,SUZ12,ACTR8,PTTG1,APOO,PKP2,TESK2,NUF2,BCL2L1,MNS1,CCNA2,SP100,SNX10,ATG4D,SEC23A,CAMSAP3,PSRC1,CAPN6,DMTN,SYNE2,TEP1,VPS4B,SYP,NUSAP1,CDCA2,ATP1B1,PYGO1,PKMYT1,AKR1E2,GABARAPL1,NIN,CEP162,PEX5,PDLIM3,SHROOM3,CORO1C,SIPA1L1,TRIOBP,RGS14,COBL,PRKAR1A,MRPS9,TTC8,WASF3,TAOK2,HSP90B1,EPS8,CDCA3,CTSZ,PKN1,SPDL1,IFT27,SIX4,RND1,CKAP5,DTX3L,PDCD10,CTSC,PTEN,CENPJ,TUBGCP6,PRC1,BAX,MAP3K7,RAG1,SPRY2,NCOA2,MSH6,SMC4,FARP2,ACBD5,LCA5,ARHGEF28,ZWINT,PAPD7,TACC1,FMN1,UBE2A,VAMP3,DIAPH2,RAB3IP,SKA1,KIF11,ABLIM2,CRTC2,DCTN6,PLOD2,SYT7,ATXN7L3,SLC35B3,SSNA1,HMGA1,CENPE,GPER1,NUP37,WDR62,NCAPG2,WDR45B,ESPL1,USP16,PHC1,CUL4B,NDC80,SUDS3,LMCD1,F11R,TAF6L,KIF2C,HDAC6,MAP1LC3B,PCNA,LRRC6,CTNNB1,DLG1,SUN3,KIF22,RAB20,ASH2L,CTTN,MYH14,TLN2,PLK1,SOD1,CENPA,CELSR2,SYNE3,ASXL1,FOPNL,C12orf65,EZR,ARHGDIB,MRPS18A,ANLN,MRPS36,CDK1,DPYSL3,KDM4D,DZIP1L,MSL1,WIPI1,MAP2,IARS2,PRKCDBP,TC2N,NR2C2,PRKAA2,USH1C,PPP1R12A,PEX6,SORBS3,RACGAP1,NCKAP1,SSX2IP,CORO1B,RB1,VASP,OCRL,PAK2,TBCD,PRKCI,LIMCH1,KNTC1,CYP26B1,MRPS33,CORO2A,FBXO8,STRADB,RANBP9,ONECUT1,PVRL2,CDCA5,PAPD5,SHROOM2,CCNB2,CTBP1,RAD21,FBXW5,GAS2L1,SORBS1,SPC25,NF2,SLC2A8,HDAC11,TP53,TDRKH,MRAS,ZMYND10,MICALL2,STIL,EMP2,SYTL2,TMSB15B,PER2,SAP130,PDGFA,TTC21B,SS18,SETDB2,KMT5C,TACC2,FRYL,KIF14,BCL6,PLK4,ESPN,EPB41L4B,LMAN1,HSPA2,CKS2,CHP1,SIRT1,PPIF,CLCN3,TAF5,FIGNL1,CDC20,MRPS35,ERBB2IP,CDC25C,DAG1,HSF4,JADE1,PTK7,PEX2,SPTBN5,CHMP4B,XRCC3,SYT13,SGOL1,REEP4,PPP2R2D,COPG1,ZC3HC1,FAM134B,PACSIN2,PINK1,TRAPPC10,ARHGEF11,KLHL13,POC1B,CIT,ERCC6L,CDCA8,HDAC9,SAC3D1,TOP2A,KIF5B,LLGL2,BUB1,RPGR,SUN2,RHOA,CENPC,CFAP46,ASPM,STMN3,COL7A1,BBS2,BCAR1,BORA,POLD3,SPAG1,MAP1B,SWAP70,SERPINA1,RND3,TADA2B,ARRB1,PKD2,PPP2R3C,GEM,CEP41,UBE2C |
| 6.603e-06 | -11.93 | BERENJENO_TRANSFORMED_BY_RHOA_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_DN | 378 | 87 | 17758 | 2588 |
LMO7,GAA,ST13,GNPDA1,HEBP1,THRA,ITPR2,MAP1LC3B,CDK14,RCN1,APLP2,IL6ST,BRI3,TWIST1,F2R,HSPA2,S100A13,NAGA,CTDSP2,CYP1B1,LAMP2,SEC23A,SMARCA2,COL6A2,CXXC5,CAPN6,CASP9,KDELR3,IDH1,SESN1,NFIX,PIAS3,TAPBP,MAOA,CTNND1,RPL22,MYL12B,GRN,CD99,PCOLCE,MRC2,SERPINE2,DNAJB2,DAP,SERPINB9,AES,COL4A5,NUCB2,FAM21C,SIX4,KIAA1161,CORO1B,GNS,OXCT1,PTEN,AIM1,COL6A1,SLC44A2,IL17RA,KLF9,SLC12A2,ITM2C,SGCB,RBMS2,P2RX4,POU6F1,CASK,IFITM3,PIK3R1,NPC2,NDRG3,TP53INP2,NFIB,CYB5A,MAGED2,TIMP3,FGFR2,NAB2,MATN2,OSMR,ARFGAP3,CTSA,PKD2,ACADM,NDFIP1,CSRP2,XDH |
| 6.649e-06 | -11.92 | LGALS3 (lectin, galactoside-binding, soluble, 3) | protein interactions | 3958 | 166 | 49 | 16036 | 2547 |
LAMP1,MRC2,TXN,LGALS3,MPZL1,CD63,MCCC1,SLC7A2,SLC1A3,SPR,BARD1,LGALS3BP,TMEM63A,CD109,CYHR1,ATP13A3,SERINC2,ACTA2,AHCY,ECE1,NPTN,SCARA3,SLC12A2,CKAP4,MCCC2,ENPP4,LAMP2,CLCN3,SOD1,AGPS,OSTM1,C1GALT1C1,SLC17A5,PTGFRN,SLC25A5,ALCAM,PDHX,EGFR,ATP1A1,PTPRJ,RPL12,DDOST,SLC9A6,DBI,ABCB1,GLB1,PLIN3,MYL12B,CAPN1 |
| 6.756e-06 | -11.91 | protein localization | biological process | GO:0008104 | 1685 | 314 | 16441 | 2455 |
SUN1,LAMP1,HSPG2,GRIK2,TAP1,GATA3,TRAPPC8,SYTL4,SNX9,PICK1,NAPG,AP1M2,DNM2,SNX16,PACSIN1,CPE,LAMP2,VPS11,KDELR3,KIF13A,AURKB,ICMT,MCFD2,RNF19B,RAB2B,ARF4,DNM1L,GNPTAB,NOD2,ARF6,F2RL1,NXT2,NFKBIE,GGA1,SEC61G,SOX9,RAB23,APBA1,FAM21C,LMNA,ATG4A,MESDC2,CALR,DOPEY2,SNX18,RPL39,NECAB3,FBXO7,SORL1,CADPS2,PIKFYVE,SYTL3,NUP85,TSPAN33,TMED2,RIMS2,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,KIF20A,CALCRL,KIF20B,GOLT1A,RHOB,STX3,AP1AR,SCARB2,TIMM8A,HTT,ZDHHC20,FAM83D,AURKA,HOOK1,NUP58,EHD1,MTM1,ARMCX3,THRA,C5orf30,PKP2,MVB12B,ZFYVE9,APPBP2,ACAP2,CDH1,TNPO2,IFIT1,ARL4D,RAB27B,DLG3,FLOT2,SNX10,ATG4D,MYO5B,SNX8,SEC23A,SEC61B,COG2,DMTN,SYNE2,VPS4B,SLC11A2,ATP1B1,PYGO1,RAB38,SNX12,ATP10D,PEX5,STX10,DDOST,SHROOM3,CORO1C,RAB29,TTC8,HSP90B1,TAOK2,MZT1,FLOT1,BTN3A1,PDIA3,SPDL1,IFT27,TSPAN17,SIX4,PDIA4,ANK1,RNF128,PPP1R10,FAM160A2,BAX,PLEKHF1,LCA5,DENND1B,RAPGEF2,PIK3R1,EIF5A2,VAMP3,RAB3IP,NEURL1B,CNTNAP1,RGPD5,MAMDC4,RPL12,RAB11FIP2,ARFGAP3,SSNA1,NUP37,CD81,WDR45B,EXPH5,UNC93B1,LTBP1,UGT8,FAF2,AGRN,ARFGEF1,UBE2Q1,MPP5,F11R,HDAC6,NUP62CL,ERP29,ZFYVE16,RAB15,NUP210,RABEP2,CTNNB1,NPNT,LMAN2L,ARL1,DLG1,SUN3,RAB20,RP2,CTTN,TLN2,TRAM1,MYRIP,S100A13,PLK1,KCNIP3,CENPA,SYNE3,EZR,ARFRP1,CDK1,VCP,OPTN,TNS4,TRAM2,TBC1D17,UEVLD,WIPI1,RAB11FIP1,KPNA2,APBA2,PCSK5,RRAGD,PEX6,ETV5,ATP6V1E2,NCKAP1,CNTNAP2,RAB6A,PGAP1,CORO1B,RB1,RINL,KIF13B,FRAS1,EXOC8,PRKCI,SRP54,WNT3A,KDELR1,SNX7,MDFI,STRADB,BTN3A2,SCRIB,NUBP1,ZDHHC3,EGFR,GNAS,TMEM30A,NFKBIA,SH3BP4,RAB31,ZDHHC7,CTSA,LTBP2,ATP1B3,SHROOM2,JAK3,CDAN1,TOB1,SNX30,RAD21,DRD1,TP53,EMP2,STIL,BCAP31,SYTL2,TTC21B,ATP6V0B,SVBP,KIF14,ZDHHC12,REEP1,SMO,ZDHHC23,BCL6,RPN2,STEAP3,LMAN1,F2R,DVL2,CHP1,BAG4,AKT1,PTPRU,AP5M1,ERBB2IP,DAG1,PEX2,CHMP4B,RPL22,ABCA1,CNEP1R1,COPG1,PACSIN2,PINK1,CD63,TSPAN15,FRMD6,LRP4,PSMD10,AIP,VPS26A,SLC9A2,ZDHHC21,KIF5B,SNX13,MLPH,ADORA1,BMP7,RRBP1,TRIM3,H2AFY,CPLX1,SYK,RPGR,CAMK2G,MYO5A,HES1,SUN2,RAB3B,FBLN5,CRB3,PRICKLE1,AKAP3,BBS2,SCG2,ARRB1,PKD2,SPCS3,ATP6V1C1,CEP41,PLOD3,RAB3IL1,ABCG1 |
| 6.777e-06 | -11.90 | LEE_NEURAL_CREST_STEM_CELL_DN | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_DN | 113 | 35 | 17758 | 2588 |
COL9A3,LZTFL1,TRIM24,GALNT12,CD82,ETV5,ARL4C,COL4A5,GDF15,CNTNAP2,CD46,BTG3,CA2,BMP7,FJX1,FUT8,CD9,HLA-C,SPRY2,ENPP4,DDB2,PRSS23,CAPN6,SAT1,SYNE2,FOS,PLEKHB1,HLA-B,MFAP3L,PROM1,PLK2,GRAMD1C,EFNA1,FZD5,MAFF |
| 6.783e-06 | -11.90 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | 170 | 47 | 17758 | 2588 |
SIGIRR,NUAK1,TRIP10,CTDSPL,ERBB2,KCTD12,PDGFRL,SORBS3,SLC1A3,CRABP2,TRIB2,SDC1,FBLN1,ARHGEF40,CCND1,APLP2,KHNYN,MGAT1,LHX6,RRBP1,CNNM4,EPHB4,SCARA3,ITM2C,NCOA2,CRTAP,EEF1D,SEMA3B,CYP26B1,OPLAH,FZD4,MAPKAPK3,PTGER4,EMP3,DUSP4,GLT8D2,STEAP1,FZD7,EGFR,FAT4,PLK2,INPP4B,PGRMC1,BMP1,AKIP1,REEP4,EHD1 |
| 6.873e-06 | -11.89 | FRASOR_TAMOXIFEN_RESPONSE_UP | MSigDB lists | FRASOR_TAMOXIFEN_RESPONSE_UP | 49 | 20 | 17758 | 2588 |
SUN2,LTBP1,LASP1,FARP1,B3GNT2,ETNK1,IL13RA1,SDC1,MECOM,ELF3,IER3,SERPINA1,CDK19,RGS3,KBTBD2,PCYOX1,MSH2,PGRMC1,CDK18,PKIA |
| 6.929e-06 | -11.88 | TIEN_INTESTINE_PROBIOTICS_24HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_DN | 215 | 56 | 17758 | 2588 |
GCLM,FAF2,HSP90B1,ARMCX3,NQO1,MAN1A2,NDRG1,ESRP1,MCTP2,PDIA3,FTH1,GDF15,NUCB2,PJA2,PHLDA1,DNAJB9,PDIA4,ELF3,CALR,VASP,MLPH,P4HB,FICD,RPL39,GOT1,HSPA13,MANF,EPHB4,TFG,PDIA6,TRAM1,TMED2,KDELR1,LAMP3,GFPT1,CLCN3,CD55,ACBD3,SAT1,BNIP3L,FNDC3A,RNF19B,RANBP9,ARF4,ARHGAP35,PTPRF,DNAJC10,BTG1,ALDH3B1,RPL12,H1F0,WIPI1,KLF5,UNC5B,HOOK1,CBX4 |
| 6.966e-06 | -11.87 | vascular endothelial growth factor receptor signaling pathway | biological process | GO:0048010 | 281 | 70 | 16441 | 2455 |
SPRED1,PSME2,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PDGFB,SPTB,PDGFA,CALM2,PSMD1,ELMO2,SHC3,PSMC2,PIK3CA,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,ITPR3,PGF,IRS2,PLCG1,FYN,JAK1,PSMD3,AXL,CTNND1,MAPK13,SPTBN5,NRG1,HSPB1,PSMC1,MAPK12,RASA2,PSMD7,PSMD10,CALM3,NCKAP1,FGF19,DUSP5,NRP2,PAK2,MAPK11,ERBB3,NCAM1,PSMA5,CAMK2G,RASGRF1,RHOA,PSMB4,MAPKAPK3,RAPGEF2,PIK3R1,CALM1,GRIN1,CYFIP2,BCAR1,PSMA4,RASA1,EGFR,MAPKAPK2,FGFR2,FGF18,ITPR1,GRIN2D,ITGAV,JAK3 |
| 6.994e-06 | -11.87 | negative regulation of cell proliferation | biological process | GO:0008285 | 633 | 135 | 16441 | 2455 |
CASP3,TRIM24,CNOT8,FBXO2,CUL1,GATA3,NDRG2,TP53I11,VASH1,TP73,CDKN2C,BTG3,RPS6KA2,TGFBR3,CTNNB1,DLG1,CYP1B1,SMARCA2,ING1,ACVR1C,ITCH,EAF2,SAV1,PRKRA,SESN1,KLF11,INPPL1,CDKN1C,SERPINE2,SOX9,NOTCH2,FBLN1,BMP2,TFAP4,RB1,GATA2,C10orf54,PDE5A,EIF2AK1,IFIT3,ILK,NFIB,TSC1,CGREF1,SH3BP4,CLMN,GDF11,TOB1,RARG,CTBP1,XDH,IRF1,NF2,IL15,S100A11,NDRG1,P3H2,INPP5D,TP53,SOD2,ERBB2,PKP2,COL18A1,FTH1,CD274,FLT3,PER2,NOV,SRPX,FABP6,BCL6,TAX1BP3,CDKN1B,ZBTB49,DAB2IP,DLG3,ETV4,F2R,CDKN2D,TIMP2,PTPRU,PTGS2,PTPRJ,PEX2,STAT1,OVOL1,PRKAR1A,NKX3-1,IGFBP6,ADGRG1,TGFBR1,PKN1,GSTP1,ETS1,CTNNBIP1,CD109,E2F7,PDCD10,ADORA1,PTEN,GPC3,BMP7,TFAP2A,BAX,CD9,BRD7,KANK2,MAPK11,KLF9,SPRY2,TGIF1,HES1,CASK,WNT10B,RAPGEF2,RGCC,EMP3,RUNX3,GPLD1,PRDX4,BTG1,ACVRL1,SCG2,FGFR2,DHRS2,CTSV,E2F1,PKD2,HMGA1,GPER1,FZD5,NDFIP1,PTGES,CD33,JARID2 |
| 7.030e-06 | -11.87 | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN | 185 | 50 | 17758 | 2588 |
CASP3,CDS2,TMEM184B,MRPS15,NDC80,ETNK1,NANS,ISOC2,SAC3D1,TOP2A,RCN1,APOBEC3B,SS18,TYMP,PSMD1,MGAT1,CTSC,BHLHE41,RRBP1,FUT8,PAPSS1,ERCC2,TFG,LMAN1,ITM2C,KDELR1,FAM69A,LAMP2,NEK4,PPIF,GFPT1,PCCB,SHMT1,MLEC,CDC20,GGH,KIF11,VCP,MAGED2,TRAM2,CASP7,SLC25A4,FA2H,WIPI1,DNM1L,ERAP1,ARFGAP3,NUP37,CCNB2,NRBP1 |
| 7.064e-06 | -11.86 | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | 190 | 51 | 17758 | 2588 |
GRN,UNC93B1,KIF3C,TXN,HSP90B1,IL15,SEC61G,DNAJC3,SOD2,PDIA3,PSME1,ISYNA1,CRABP2,MERTK,PHLDA1,FAM46C,CMTM6,CDK14,SPP1,NOV,PFKL,RALB,ARL1,RRBP1,CST3,CKS1B,H2AFY,ECE1,NAGA,GCLC,SEPT6,ITCH,CASP9,CAPNS1,ARFRP1,NPC2,FNDC3A,DOCK5,RNF19B,STX3,MAP1B,CMTM7,FUCA1,NUCB1,MPRIP,CASP7,ACYP1,TMEM30A,ARFGAP3,CD81,ISOC1 |
| 7.075e-06 | -11.86 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP | 195 | 52 | 17758 | 2588 |
KLF2,LASP1,DLGAP5,EPAS1,IQGAP1,NDC80,GATA3,RACGAP1,KIF2C,CCNB1,BARD1,PCBP1,IL18R1,HLA-A,EPS8L2,CAPN2,APOBEC3B,FUT8,PRC1,KIF22,MAPK11,KNTC1,LOXL1,GFI1,SMC4,FAM69A,TAF5,CASK,ARAP2,MLEC,PSMB4,TMEM43,TACC1,ASPM,STAT4,NUSAP1,POLD3,KIF11,RASGRP2,OPTN,SLCO4A1,P4HA2,CSTF2,PPP1CB,HDAC1,STK39,CENPE,PIEZO1,CCNB2,ESPL1,MELK,EHD1 |
| 7.075e-06 | -11.86 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP | 195 | 52 | 17758 | 2588 |
GAA,NFKBIE,SLC2A8,BLVRB,EFHD2,IL13RA1,PLA2G16,SEPP1,GSTP1,SIRPA,BMP2K,LMNA,SGPL1,C7orf49,LYPD3,DPYSL2,CST3,FDXR,PLCG2,CAPG,DAPK1,VAT1,STEAP3,LIMCH1,AHCY,RAB20,LGMN,NAGA,KCTD3,MYO5A,FAH,GPX4,LAMP2,PDGFC,FADS2,MMD,MBNL3,NPC2,POR,ADRBK2,CD83,FUCA1,LRRC42,IL1R1,PLK2,TCEAL4,MAOA,DYSF,CTSA,PLXND1,ZMIZ1,CD81 |
| 7.075e-06 | -11.86 | GSE29618_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DN | 195 | 52 | 17758 | 2588 |
S100A11,CD63,CAST,CTSB,BLVRB,SOD2,NOTCH2,CAPN2,GNS,TIMP1,MGAT1,DPYSL2,DAPK1,H2AFY,IL17RA,RAB20,MTMR11,TIAM1,NAGA,S100A6,QSOX1,RHOA,MCTP1,MPP1,PLAUR,VAMP3,CDA,BLVRA,ZFAND5,ULK2,CRISPLD2,PTGS2,ALDH3B1,RBM47,HPSE,RCBTB2,RAB31,ZDHHC7,PPP2R3C,CTSA,PLIN3,ZMIZ1,ARPC2,NDFIP1,SLC27A3,SLC31A2,LTA4H,RTN3,AHR,CPPED1,PCSK5,CD33 |
| 7.075e-06 | -11.86 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | 195 | 52 | 17758 | 2588 |
CASP3,TXN,PARP12,ST14,FAM129B,SERPINB9,ERI2,CYB561,IL18,HMGN3,TGFBR1,B4GALT4,SNX9,PHLDA1,EPCAM,DNPEP,IGSF9,FOSB,CAPG,TUBG1,TNFRSF18,WWP1,MDFIC,IL10RB,FAH,METAP2,PLSCR1,CORO2A,MBNL3,PRKRA,ALCAM,SEC14L2,CMTM7,SCRN2,CD83,GABARAPL1,RGS9,SWAP70,PTPRJ,UAP1,AREG,AXL,LRIG1,MATN2,RAB31,PRDM5,TDRD7,PLXND1,TRPC3,CD81,LRRC57,CSRP2 |
| 7.084e-06 | -11.86 | MODULE_118 | MSigDB lists | MODULE_118 | 395 | 90 | 17758 | 2588 |
PAX6,DLGAP5,HSPG2,NQO1,S100A11,FOXM1,PTTG1,NDC80,C5orf30,NRG2,CCNB1,CARD10,CHPF,IER3,DAPK2,EPCAM,CDKN2C,ZYX,PCNA,CCNA2,SRPX,TACC2,KIF14,IFIT1,RNASEH2A,BTBD3,IL1RAP,CKS2,CYP1B1,PLK1,VPS11,SGCE,CENPA,PFKFB2,S100A4,CDC20,ARHGDIB,LOXL2,PKMYT1,CCNF,ALCAM,CDK1,LCP1,DPYSL3,ZMPSTE24,MDK,PAFAH1B3,TBX1,MAFF,ABCA1,GRN,ENO2,ITGA6,BIK,GDF15,M6PR,TOP2A,RAC2,SPP1,ITGA3,CYR61,CTSC,KCNN4,GPC3,CD22,CALD1,IGFBP2,ALDH7A1,KNTC1,TMX1,IGSF3,HMMR,FADS2,ZWINT,PRSS23,MYBL2,EMP3,GGH,KIF11,FOS,PROM1,TIMP3,PLOD2,RND3,E2F1,RAB31,UBE2C,CCNB2,CSRP2,CD33 |
| 7.436e-06 | -11.81 | RODWELL_AGING_KIDNEY_UP | MSigDB lists | RODWELL_AGING_KIDNEY_UP | 445 | 99 | 17758 | 2588 |
LAMP1,PSME2,RPS6KA1,TAP1,MRAS,FAM198B,MICALL2,VASH1,FAM101B,TMPRSS4,SYTL2,NOV,TYMP,P4HB,PIK3CD,TSPAN1,LOXL1,PTPRE,SULF2,TIMP2,TMEM43,PLEKHO1,HTATIP2,ARHGDIB,C15orf39,ITPR3,CMTM7,SOCS3,NFIX,TRIM47,CARHSP1,TAPBP,STAT6,CORO1C,AXL,TSPAN18,NFKBIZ,AKNA,REEP4,GRN,DDX58,SCN5A,CTHRC1,LASP1,RUNX2,PARP12,SERPINE2,NUAK1,PARP14,HLA-E,ZCCHC24,HLA-F,DGKQ,CCM2,ARL4C,SAMD9,SLC1A3,DOCK11,HLA-A,PDIA4,DTX3L,RAC2,CXCL16,TIMP1,IRAK1,MGAT1,BHLHE41,FDXR,DRAM1,FXYD5,IL17RA,ARVCF,TAGLN2,C10orf54,HLA-C,MOXD1,ITM2C,CCDC88A,ABCC1,DLGAP1,USP31,NUB1,EMP3,PRICKLE1,RUNX3,ANTXR1,FAS,HLA-B,SLC6A6,LDLRAP1,PROM1,RPL12,RIN3,NLRC5,RAB31,PGM2L1,OSMR,PLOD3,TMEM173 |
| 7.439e-06 | -11.81 | mitotic cell cycle phase transition | biological process | GO:0044772 | 297 | 73 | 16441 | 2455 |
CCNE2,ACVR1,CEP70,FOXM1,TUBB4B,PSME2,CUL1,PSME1,CCNB1,PRKACA,CDK14,CDKN2C,CCND1,WEE1,CCNA2,PCNA,PSMD1,CNTRL,CEP78,PSMC2,PLK4,DNM2,TUBG1,CDKN1B,CDKN2D,TUBA4A,PLK1,PRKAR2B,PKMYT1,CDC25C,CDK1,OPTN,PRIM1,PLK2,PSMD3,PPP1CB,KLF11,PSMC1,PPP2R2D,USH1C,PPP1R12A,CIT,EPS8,PSMD7,PSMD10,NES,CKAP5,RB1,E2F7,CENPJ,TUBGCP6,NEK2,CKS1B,IQGAP3,GFI1,PSMA5,CAMK2G,PSMB4,WNT10B,MYBL2,BORA,PSMA4,CDCA5,E2F1,ABCB1,AURKA,SSNA1,CEP41,NDE1,CCNB2,UBE2C,MELK,DMPK |
| 7.453e-06 | -11.81 | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | MSigDB lists | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | 352 | 82 | 17758 | 2588 |
ST13,UGP2,HEBP1,PTTG1,EGR3,BARD1,CENPN,BCAP31,PCNA,DPYSL2,FOSB,PDIA6,APOBEC3G,CKS2,METAP2,NEK4,SH3BGRL,COX11,NUSAP1,MRPS35,GLO1,CDK1,PRIM1,ALDH5A1,LRIG1,IARS2,RPL22,LTA4H,HSPB1,RTN3,E2F8,ISOC1,CD99,ALDH6A1,ATP9A,PSMD10,RACGAP1,INTS8,NUCB2,PSIP1,MYO5C,TOP2A,OXCT1,PAK2,PRC1,FBXL14,CD9,CKS1B,ECI2,AHCY,CITED2,KCTD3,HMMR,PCCB,ZWINT,RHOA,MRPS33,MPP1,TCFL5,WHSC1,GGH,MEST,KIF11,FOS,CYB5A,FRMD4B,PRDX4,PRDX3,PRPS2,TCEAL4,MDH1,PKD2,FHL1,HMGA1,ACADM,NUP37,TMEM14A,CCNB2,TBC1D4,CTBP1,MELK,CSRP2 |
| 7.505e-06 | -11.80 | lung | COSMIC cancer mutations | lung | 17159 | 2531 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,CPLX1,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,MDFI,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,DRP2,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TM2D2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,TMEM64,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,IL22RA1,VPS26A,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,REPS2,CAPN12,GPR107,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,ACBD3,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,FAM109A,NEURL1B,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 7.546e-06 | -11.79 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | 156 | 44 | 17758 | 2588 |
PLA2G4A,ANXA3,AGRN,ENO2,NUAK1,EPS8,ARL4C,SRPX2,ICAM1,MECOM,IER3,RCN1,RAC2,SRPX,CTSC,COL6A1,CAPG,ACTA2,TACSTD2,ECE1,LAMP2,PCDH1,ALDH2,MAPKAPK3,FHL2,EMP3,ARHGDIB,ATP1B1,LOXL2,CYFIP2,TP53I3,TCN2,NMT2,RHOB,GLCE,PGF,TRAM2,UAP1,PLOD2,AXL,STAT6,LTBP2,ITGAV,PKIA |
| 7.747e-06 | -11.77 | VANTVEER_BREAST_CANCER_ESR1_UP | MSigDB lists | VANTVEER_BREAST_CANCER_ESR1_UP | 161 | 45 | 17758 | 2588 |
MAN2B2,LZTFL1,HDAC11,C5orf30,GATA3,COX6C,C3orf18,ECI1,MYO5C,SLC16A6,IL6ST,KIF13B,FUT8,FAM63A,TMBIM6,FAM102A,HMGCL,TSPAN13,ERBB3,MYLIP,MAST4,KCTD3,MCCC2,CERS2,FARP2,SUSD3,CXXC5,SYBU,NPDC1,SEC14L2,MAGED2,RBM47,ACADSB,KIAA0141,FAAH,HTT,NAT1,LRIG1,FAM110C,APPL2,KIF12,CPEB2,PRR15,FOXA1,FAM134B |
| 7.789e-06 | -11.76 | AMUNDSON_GENOTOXIC_SIGNATURE | MSigDB lists | AMUNDSON_GENOTOXIC_SIGNATURE | 100 | 32 | 17758 | 2588 |
PHLDA1,DUSP5,SAC3D1,ELF3,CDKN2C,PCNA,SP100,SIVA1,IRF2,BUB1,ACSL4,GFI1,SPRY2,NFE2L3,GFPT1,DDB2,ZWINT,CENPA,TAF5,PKMYT1,FOS,SEMA4D,AXL,PPP2R4,FGF18,BMP1,NR4A3,AURKA,KPNA2,GEM,RARG,GAB1 |
| 7.813e-06 | -11.76 | breast-carcinoma | COSMIC cancer mutations | breast-carcinoma | 15843 | 2366 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,TGOLN2,DPP8,FAM46C,SPSB1,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,NOD2,TMOD2,STARD13,ANXA11,ZNF720,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,ATG4A,RAC2,SH3D21,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,CNGA1,PANX2,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,DGAT2,OSCP1,TMEM173,DMPK,WDR63,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,CORO1C,AXL,FAM149A,PRIMA1,SLC25A30,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,MGAT5B,SLC9A3R2,PLS3,BTG3,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,SEMA3A,CCNB2,CDAN1,USP43,TMX4,RHPN2,PCBP1,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,MSH2,TMEM51,PRKG1,ADCK2,OSTF1,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,TRIQK,FZD7,POPDC3,ACAD10,NGFRAP1,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,E2F7,TMEM87B,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,ARHGEF37,METTL7A,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,TOX2,RRBP1,ARVCF,C12orf75,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,RGS14,ARNT,TNRC6C,NKX3-1,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,EIF5A2,ELOVL3,PLEKHA7,DBR1,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,CYBRD1,TRIM2,AGRN,PPM1J,EPHA4,TP53I11,HDAC6,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,FAM212B,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,MOSPD3,EPN3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,C1orf116,CYP26A1,RAD23A,CDK14,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,CDC20,DUOX1,ATP1A1,PRRT4,RTN4RL1,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,NKRF,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,CRB3,NR3C1,AMFR,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,CASP9,HSPA12A,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,CDK17,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,SLC1A3,NOTCH2,MECOM,SNX18,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,B3GNT7,KIAA1841,MMD,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,AKIRIN1,SNTA1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,CNPY3,OSGIN1,PCCB,CASK,SHMT1,MPP1,DENND1B,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,HEBP1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,RAB20,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,LOXL1,F2R,SCYL3,FRS3,MAP3K3,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,CCDC24,CDS2,SORT1,FRMD6,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,FAM219A,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,SNX9,CMTM6,CARD10,LTBP3,ZNF275,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,GINS4,PLCG1,ENPP1,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,MEGF8,RIMS3,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,C11orf45,IL1R1,FNTA,CLMN,TMEM159,CBX5,RUSC1,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,PTTG1,RHBDL3,GRK6,FAM91A1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,COX20,GIGYF1,EBF2,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,PROM1,RPL12,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,TMEM131,PHC1,ILDR1,LMCD1,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KRT80,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,PRSS8,RMND5A,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,WDR44,PPME1,VAT1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,PTGS2,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,LBR,AIP,PARM1,IL22RA1,VPS26A,SH2D4A,FZD6,NRP2,M6PR,CD109,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,HMGN5,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,TNFRSF19,S100A2,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,C1orf21,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,CAPN12,REPS2,GPR107,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,TMEM170B,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,HAGHL,SLC27A3,COBL,PRKAR1A,IER5L,PLSCR4,CENPI,SLC41A1,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FJX1,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,COMMD5,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,CEP78,CTTN,STK35,LAMP3,LAP3,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,C3orf52,BTBD19,TMTC2,CD40,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,WNT10B,RUNX3,FAM73B,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,MMADHC,FBXO2,DHX8,LGI3,IL18,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,ARHGAP42,PQLC2,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,SLC37A1,CALCRL,PLS1,MEST,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,TESK2,PKP2,PRKACA,APC2,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,FARP1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,FMN1,FAM160A1,CTNNAL1,GRIN1,MYEOV,FAM109A,CRISPLD2,ABLIM2,GALNT3,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,FAM199X,CUL4B,SUDS3,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,SCN2A,MINPP1,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,PKM,GLT8D2,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,AMMECR1,CCDC69,GRIN2D,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,TMEM184B,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,FOPNL,RNF165,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,APBA2,PSMC1,MIIP,GRN,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,SLC6A6,UTP14C,CGREF1,PAPD5,PITPNA,KLF7,FBXW5,GAS2L1,ZSWIM5,IL15,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,OSTM1,DUSP4,DOCK5,KCTD2,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM |
| 7.837e-06 | -11.76 | microtubule binding | molecular function | GO:0008017 | 197 | 53 | 16491 | 2452 |
GAS2L1,KIF3C,NDRG1,KIF23,RACGAP1,KIF2C,HDAC6,KIF26A,APC2,MAP1LC3B,KIF5B,STIM1,DPYSL2,KIF13B,KIF14,REEP1,TUBGCP6,PRC1,DNM2,KLC3,KIF22,CLIP2,CCDC88A,CHP1,PLK1,DPYSL5,CAMSAP3,SUN2,PSRC1,KIFC2,KIF20A,CAPN6,FMN1,UXT,SYBU,KIF1C,EZR,KIF13A,KIF20B,NUSAP1,SKA1,KIF11,GABARAPL1,MAP1B,FNTA,MAP2,TRAF3IP1,FAM83D,CENPE,KIF12,NDE1,RGS14,REEP4 |
| 7.904e-06 | -11.75 | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | 299 | 72 | 17758 | 2588 |
CCNE2,CASP3,TMX4,TP53,ERBB2,OSR2,TNFSF9,ECI1,PER2,CDKN2C,PCNA,IFIT1,PPP1CA,HSPA2,S100A13,CTH,TUBA4A,CYP1B1,PPIF,SAT1,NFE2L1,PKMYT1,CLCN2,TP53I3,GABARAPL1,MDK,PGF,SLC25A4,PAFAH1B3,AGPAT2,GPRC5B,ACYP1,PPP2R5D,CBX4,CDKN1C,IGFBP6,NFKBIE,GCAT,HLA-F,HLA-E,ADO,ASL,PDCL,GSTP1,SPR,HLA-A,SAC3D1,CDK16,MGAT1,FDXR,FBXL14,TRIM21,TMBIM6,ERCC2,NPTXR,EEF1D,EPHX1,SHMT1,NR4A1,MICB,MYBL2,RNF113A,RHOB,PITX2,BTG1,NAT1,E2F1,EFNA1,SHOX2,TOB1,DMPK,IRF1 |
| 8.198e-06 | -11.71 | LI_INDUCED_T_TO_NATURAL_KILLER_UP | MSigDB lists | LI_INDUCED_T_TO_NATURAL_KILLER_UP | 294 | 71 | 17758 | 2588 |
S100A11,FAM129B,EGR3,VASH1,PRR7,ECI1,SYTL2,IER3,PDGFA,DAPK2,KHNYN,FAM46A,CTGF,OSBPL3,PLCG2,CAPG,TNFRSF18,TIAM1,F2R,SULT2B1,S100A13,SMAGP,SUSD3,SEC61B,S100A4,CORO1C,SERPINB6,MLKL,ARF6,NRGN,LASP1,ARAP3,DYRK3,SERPINE2,LGALS3,CD63,ASAH1,DUSP5,IL18R1,LGALS3BP,LMNA,CAPN2,AIM1L,SPP1,SNX18,AIM1,CD9,FAM63A,FXYD5,SGK1,OSTF1,S100A6,GCNT1,SYPL1,PLSCR1,IFITM3,MAPKAPK3,LITAF,FHL2,FURIN,CAPNS1,PRRC1,PIM3,PRDX4,ENDOD1,SLC2A6,C1orf21,LRRK1,TMEM120A,ARSB,NDFIP1 |
| 8.198e-06 | -11.71 | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | MSigDB lists | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | 294 | 71 | 17758 | 2588 |
PLA2G4A,FAM171B,FAM92A1,TRIM24,IL18,FLT3,PLS3,RCN1,KCTD15,SLC39A10,F2R,BTBD3,SCN3A,SMARCA2,ERMP1,SLC39A8,GALNT7,TANC1,ZNF618,DPYSL3,HLF,AREG,ANKRD6,HOXA9,ZNF165,HSPB1,F2RL1,ZMAT1,CTHRC1,RUNX2,GOLIM4,SLC16A14,FRMD6,ATP9A,SLC25A27,PM20D2,ISYNA1,C11orf95,SEPP1,BEX2,MYO5C,RAVER2,CD109,TNS3,GATA2,SPIN4,DAPK1,H2AFY,LIMCH1,FAIM,MAST4,ITM2C,KCTD3,WBP5,ABCC1,SYPL1,PDGFC,PGBD1,MEST,PRDX4,FRMD4B,DDAH1,PROM1,CCDC6,PPM1H,SH3BP4,TCEAL4,PKD2,FHL1,WDR91,CBX5 |
| 8.273e-06 | -11.70 | GSE14000_UNSTIM_VS_4H_LPS_DC_DN | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_DN | 186 | 50 | 17758 | 2588 |
PLA2G4A,DDX58,LRRFIP2,TTC39B,IL15,PARP14,SOD2,GMPR,UBE2Z,HERC5,CD274,DUSP5,NFAT5,DTX3L,FBXO7,IRF2,TRIM21,IFIT1,KLF9,OAS3,ETV7,CKAP4,PARP9,KIAA0040,MICB,COQ10B,USP18,NUB1,PTGER4,RUNX3,PIM3,IFIT3,PI4K2B,CASP7,C19orf66,NFKBIA,NLRC5,NR4A3,TDRD7,IRF7,NFKBIZ,CMPK2,SLC31A2,IFIH1,IFI6,RARG,MELK,CSRP2,IRF1,WDR63 |
| 8.292e-06 | -11.70 | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDM_DN | 191 | 51 | 17758 | 2588 |
FAM89A,ARHGEF3,INPPL1,ACVR1,TXN,TBC1D1,RUSC2,EPHA4,OSGIN2,GABRG2,P2RX7,NDRG2,PLXNA1,CCNL1,KREMEN1,IER3,ZFYVE16,ATP6V0B,EFR3A,FAM20C,DPYSL2,FICD,BHLHE41,ARL1,PAPSS1,OSTF1,ACSL4,MAP3K7,TBC1D10B,QSOX1,IFITM3,AMFR,PLAUR,SAT1,DIAPH2,CALCRL,ARFRP1,PIM3,RAD17,FZD7,HLA-B,RGS9,RBL1,COL13A1,NFKBIA,NAB2,TDRD7,PPP1CB,HDAC1,ITGAV,GEM |
| 8.292e-06 | -11.70 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | 191 | 51 | 17758 | 2588 |
KLF2,ARHGEF3,PINK1,USH1C,ALDH6A1,FAM129B,CAST,UBASH3B,HAL,SELL,IL27RA,MGST2,NUCB2,TRIB2,SNN,FAM101B,PARM1,CEP97,AP1M2,IL6ST,SLC44A1,CAPG,UBE2J1,IL17RA,TAX1BP3,ERBB3,PXMP4,CPE,DOCK4,MBP,B9D2,ACVR1C,ADCK3,CALCRL,CD40,SESN1,NFIX,OSBPL2,NAAA,TBC1D17,STK38,LRIG1,APPL2,SH3BGRL2,USF2,CBX7,LRRC57,SNX30,KLF7,ARHGEF4,TMEM131 |
| 8.426e-06 | -11.68 | positive regulation of phosphorus metabolic process | biological process | GO:0010562 | 1138 | 222 | 16441 | 2455 |
CCNC,TXN,ACVR1,TRIM5,CAMKK1,EPHA4,NRG2,PSME1,IL18,NENF,CCNB1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,PAK6,PSMD1,CTNNB1,CTGF,NPNT,SHC3,IL6ST,PSMC2,IL31RA,PIK3CA,DLG1,TNFRSF18,SLC39A10,RASGRP1,PLK1,NEK4,SOD1,PRKAR2B,CDK1,VCP,EDNRA,PLCG1,GPRC5B,AREG,ANKRD6,TBX1,PPP2R4,MADD,NOD2,MAP3K11,PRKCDBP,CAB39,F2RL1,PSMC1,GAB1,PRKAA2,PIFO,PPP1R12A,ITGA6,RASA2,SOX9,PRKAA1,PSMD7,CALM3,SORBS3,TEC,DUSP5,BMP2,IGF1R,CYR61,PAK2,MAP3K9,FNIP1,MDFIC,BRAT1,NPTN,MYDGF,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,GPR161,MDFI,MMD,MAPKAPK3,CALM1,KCTD20,PDE5A,STRADB,CALCRL,ILK,PSMA4,EGFR,RASA1,CDK5R1,FAS,GNAS,MAPKAPK2,BCAR3,PRKAG2,INSR,SEMA4D,PELI2,PLPP3,CSF1,STK39,EFNA1,GDF11,MAP3K5,JAK3,XDH,DRD1,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,FLT3,EMP2,STIL,PDGFA,CCND1,ST5,RALB,KIF14,DAB2IP,RASGEF1A,F2R,HSPA2,DVL2,FRS3,MAP3K3,SIRT1,TIMP2,PSRC1,BAG4,RIPK2,AKT1,FZD4,PFKFB2,CDCA2,CD40,MAP3K6,FZD7,IRS2,FYN,JAK1,PPP2R5A,STK26,PSMD3,WFS1,KIAA1804,SLC27A1,EFNA5,NRG1,SPTBN5,CNEP1R1,ARNT,ABCA1,PRKAR1A,PINK1,NKX3-1,TAOK2,TAB3,TRAF2,SDC4,GNAL,FLOT1,PSMD10,TGFBR1,GDF15,PKN1,FGF19,ICAM1,PDCD10,ADORA1,IRAK1,PTEN,KNDC1,BMP7,BAX,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,HES1,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,YES1,BCL10,GPLD1,BANK1,FGFR2,ACVRL1,FGF18,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,PKD2,GPER1,LRRK1,CENPE,FZD5,CD81 |
| 8.426e-06 | -11.68 | positive regulation of phosphate metabolic process | biological process | GO:0045937 | 1138 | 222 | 16441 | 2455 |
CCNC,TXN,ACVR1,TRIM5,CAMKK1,EPHA4,NRG2,PSME1,IL18,NENF,CCNB1,SNX9,PDGFB,ERP29,CARD10,SPTB,GRM5,TP73,CALM2,PAK6,PSMD1,CTNNB1,CTGF,NPNT,SHC3,IL6ST,PSMC2,IL31RA,PIK3CA,DLG1,TNFRSF18,SLC39A10,RASGRP1,PLK1,NEK4,SOD1,PRKAR2B,CDK1,VCP,EDNRA,PLCG1,GPRC5B,AREG,ANKRD6,TBX1,PPP2R4,MADD,NOD2,MAP3K11,PRKCDBP,CAB39,F2RL1,PSMC1,GAB1,PRKAA2,PIFO,PPP1R12A,ITGA6,RASA2,SOX9,PRKAA1,PSMD7,CALM3,SORBS3,TEC,DUSP5,BMP2,IGF1R,CYR61,PAK2,MAP3K9,FNIP1,MDFIC,BRAT1,NPTN,MYDGF,PIM1,NCAM1,WNT3A,CCDC88A,PSMA5,GPR161,MDFI,MMD,MAPKAPK3,CALM1,KCTD20,PDE5A,STRADB,CALCRL,ILK,PSMA4,EGFR,RASA1,CDK5R1,FAS,GNAS,MAPKAPK2,BCAR3,PRKAG2,INSR,SEMA4D,PELI2,PLPP3,CSF1,STK39,EFNA1,GDF11,MAP3K5,JAK3,XDH,DRD1,PROM2,SPRED1,AVPI1,IL15,IQGAP1,PSME2,TP53,ERBB2,P2RX7,RASGRP3,CCNL1,PRKACA,FLT3,EMP2,STIL,PDGFA,CCND1,ST5,RALB,KIF14,DAB2IP,RASGEF1A,F2R,HSPA2,DVL2,FRS3,MAP3K3,SIRT1,TIMP2,PSRC1,BAG4,RIPK2,AKT1,FZD4,PFKFB2,CDCA2,CD40,MAP3K6,FZD7,IRS2,FYN,JAK1,PPP2R5A,STK26,PSMD3,WFS1,KIAA1804,SLC27A1,EFNA5,NRG1,SPTBN5,CNEP1R1,ARNT,ABCA1,PRKAR1A,PINK1,NKX3-1,TAOK2,TAB3,TRAF2,SDC4,GNAL,FLOT1,PSMD10,TGFBR1,GDF15,PKN1,FGF19,ICAM1,PDCD10,ADORA1,IRAK1,PTEN,KNDC1,BMP7,BAX,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,HES1,PDGFC,RASGRF1,ADAM17,PSMB4,RAPGEF2,PLAUR,GRIN1,RGCC,YES1,BCL10,GPLD1,BANK1,FGFR2,ACVRL1,FGF18,RAP2C,RYK,ARRB1,PPP2R3C,GRIN2D,PKD2,GPER1,LRRK1,CENPE,FZD5,CD81 |
| 8.640e-06 | -11.66 | fibroblast growth factor receptor signaling pathway | biological process | GO:0008543 | 293 | 72 | 16441 | 2455 |
SPRED1,PSME2,IQGAP1,NRG2,ERBB2,RASGRP3,PSME1,ITPR2,PRKACA,PDGFB,SPTB,PDGFA,CALM2,PSMD1,CTGF,SHC3,PSMC2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,PRKAR2B,AGO4,CBL,ITPR3,IRS2,PLCG1,FYN,JAK1,PSMD3,NRG1,SPTBN5,GAB1,PSMC1,PRKAR1A,TNRC6C,RASA2,PSMD7,PSMD10,CALM3,PHLPP1,FGF19,DUSP5,ADRBK1,PTEN,FLRT3,ERBB3,NCAM1,SPRY2,PSMA5,CAMK2G,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,FGF18,ITPR1,GRIN2D,JAK3 |
| 8.728e-06 | -11.65 | WIELAND_UP_BY_HBV_INFECTION | MSigDB lists | WIELAND_UP_BY_HBV_INFECTION | 96 | 31 | 17758 | 2588 |
PARP12,LGALS3,LAP3,PSME2,HLA-E,PBK,HLA-F,CTSB,PTTG1,SOD2,ARHGDIB,PSME1,DENND2D,HLA-A,CD83,HLA-B,RAC2,TAPBP,CTSC,PRC1,STAT1,DRAM1,RAB31,AURKA,RAB20,KPNA2,RFX5,HLA-C,PIK3CD,UBE2C,GM2A |
| 8.989e-06 | -11.62 | regulation of MAPK cascade | biological process | GO:0043408 | 778 | 160 | 16441 | 2455 |
GRIK2,TRIM5,EPHA4,NRG2,NDRG2,PSME1,NENF,PDGFB,ERP29,SPTB,GRM5,TP73,CALM2,PAK6,PSMD1,CTNNB1,CTGF,NPNT,SHC3,RGS3,PSMC2,DLG1,DUSP10,RASGRP1,SOD1,TNIP1,ITCH,PBK,EZR,CDK1,PLCG1,ANKRD6,TBX1,MADD,NOD2,MAP3K11,PRKCDBP,SPRY4,F2RL1,PSMC1,GAB1,RASA2,PRKAA1,PSMD7,CALM3,SORBS3,PHLPP1,FBLN1,DUSP5,MECOM,BMP2,IGF1R,CYR61,PAK2,MAP3K9,SORL1,MDFIC,MYDGF,NCAM1,PSMA5,MDFI,MAPKAPK3,CALM1,PDE5A,STRADB,ILK,PSMA4,RANBP9,EGFR,RASA1,FAS,MAPKAPK2,INSR,PELI2,FAM83D,EFNA1,GDF11,MAP3K5,JAK3,XDH,SPRED1,AVPI1,NF2,FOXM1,PSME2,ERBB2,P2RX7,RASGRP3,FLT3,PDGFA,ST5,DACT1,DAB2IP,APIP,RASGEF1A,F2R,DVL2,FRS3,MAP3K3,TIMP2,AKT1,RIPK2,FZD4,DUSP4,CD40,DAG1,MAP3K6,C3orf33,FZD7,IRS2,FYN,PTPRJ,JAK1,STK38,PSMD3,KIAA1804,NRG1,SPTBN5,RGS14,TAOK2,PINK1,TAB3,TRAF2,PSMD10,GDF15,TGFBR1,PKN1,TRIB2,GSTP1,FGF19,ICAM1,PDCD10,IRAK1,ADORA1,PTEN,BMP7,MAPK11,ERBB3,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,DUSP1,RASGRF1,PSMB4,RAPGEF2,GRIN1,MAPK8IP1,LEMD2,BANK1,FGFR2,FGF18,RYK,ARRB1,GRIN2D,GPER1,FZD5,CD81,HIPK3 |
| 9.028e-06 | -11.62 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | 531 | 114 | 17758 | 2588 |
EXPH5,TRIM2,UGT8,TXN,ST13,CRYM,NDRG1,SLC25A13,MORF4L2,PLA2G16,PJA2,OAT,KBTBD11,SDC1,ECI1,CDK14,CDS1,PLS3,EPCAM,APLP2,WEE1,CDH1,METTL7A,VAT1,GOT1,TECR,MINPP1,F2R,BTBD3,CTH,NEK4,SEC23A,SOD1,RFK,DSTN,ACO1,COX11,PRKRA,H2AFV,IDH1,PDHX,GABARAPL1,MFAP3L,FYN,ALDH5A1,SLC25A4,DDOST,DNM1L,WWTR1,MAOA,SERPINI1,HSPB1,NR3C2,PRKAR1A,CDKN1C,ALDH6A1,FAM169A,DAP,ITGA6,EPS8,NCKAP1,PDXDC1,PPP2R3A,DNAJB9,PARM1,SLC25A36,KIAA0895,ADD3,CA2,OXCT1,IGF1R,GPC3,CD9,PRKCI,TMBIM6,WWP1,AHCY,IGFBP2,HMGCL,HSPA13,ERBB3,ALDH3A2,IGSF3,FAH,SYPL1,PMPCB,PGM1,SHMT1,ALDH2,PIK3R1,AK4,FBXO9,GGH,KIAA1109,YES1,FNDC3A,CYB5A,FECH,FUCA1,SLC4A4,ACADSB,PRDX3,NR1D2,SETD3,FAM3C,PGRMC1,ABCB1,CCDC69,MDH1,ACADM,CTBP1,TOB1,OCLN,RPS6KA3 |
| 9.064e-06 | -11.61 | cellular macromolecule localization | biological process | GO:0070727 | 1151 | 224 | 16441 | 2455 |
SUN1,LAMP1,EXPH5,UNC93B1,FAF2,UGT8,AGRN,GRIK2,TAP1,TRAPPC8,F11R,MPP5,SYTL4,HDAC6,SNX9,ERP29,PICK1,ZFYVE16,NAPG,RAB15,AP1M2,CTNNB1,ARL1,DLG1,SNX16,SUN3,RAB20,CTTN,TLN2,PACSIN1,TRAM1,MYRIP,CPE,PLK1,VPS11,KCNIP3,CENPA,SYNE3,KDELR3,EZR,ARFRP1,KIF13A,AURKB,ICMT,CDK1,RAB2B,ARF4,VCP,OPTN,DNM1L,WIPI1,GNPTAB,KPNA2,ARF6,RRAGD,NFKBIE,GGA1,PEX6,SEC61G,SOX9,ETV5,RAB23,RAB6A,CNTNAP2,APBA1,PGAP1,LMNA,ATG4A,MESDC2,CORO1B,CALR,RB1,SNX18,RPL39,KIF13B,FBXO7,EXOC8,PRKCI,SRP54,SORL1,PIKFYVE,WNT3A,SYTL3,NUP85,TSPAN33,TMED2,RIMS2,MDFI,KDELR1,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,STRADB,KIF20B,NUBP1,ZDHHC3,RHOB,EGFR,STX3,AP1AR,SCARB2,TIMM8A,HTT,TMEM30A,ZDHHC20,NFKBIA,SH3BP4,RAB31,FAM83D,ZDHHC7,AURKA,CTSA,LTBP2,ATP1B3,JAK3,TOB1,DRD1,EHD1,RAD21,ARMCX3,THRA,TP53,PKP2,EMP2,STIL,BCAP31,ZFYVE9,APPBP2,SYTL2,TTC21B,ACAP2,CDH1,ZDHHC12,REEP1,BCL6,ZDHHC23,SMO,TNPO2,RPN2,IFIT1,LMAN1,RAB27B,DLG3,F2R,SNX10,FLOT2,DVL2,CHP1,ATG4D,SNX8,SEC23A,SEC61B,BAG4,AKT1,PTPRU,SYNE2,ATP1B1,RAB38,PYGO1,ATP10D,DAG1,PEX5,STX10,DDOST,PEX2,CHMP4B,RAB29,RPL22,CNEP1R1,COPG1,PINK1,PACSIN2,HSP90B1,TAOK2,MZT1,CD63,TSPAN15,FRMD6,LRP4,FLOT1,PDIA3,PSMD10,SPDL1,IFT27,TSPAN17,AIP,VPS26A,SIX4,ZDHHC21,SNX13,ANK1,ADORA1,MLPH,RNF128,PPP1R10,BMP7,BAX,PLEKHF1,H2AFY,SYK,RPGR,MYO5A,SUN2,HES1,RAB3B,FBLN5,CRB3,RAPGEF2,PIK3R1,VAMP3,PRICKLE1,RAB3IP,BBS2,CNTNAP1,RGPD5,RPL12,ARFGAP3,SSNA1,PKD2,SPCS3,CD81,WDR45B |
| 9.312e-06 | -11.58 | DAP12 interactions | REACTOME pathways | R-HSA-2172127 | 340 | 81 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PDGFB,PRKACA,SPTB,CALM2,PDGFA,PSMD1,SHC3,PLCG2,PSMC2,PIK3CA,CDKN1B,DUSP10,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,DUSP4,ITPR3,IRS2,PLCG1,FYN,JAK1,PPP2R5A,PSMD3,MAP3K11,NRG1,SPTBN5,PPP2R5D,PSMC1,GAB1,PRKAR1A,TNRC6C,RASA2,HLA-E,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,ADRBK1,PTEN,ERBB3,HLA-C,NCAM1,SYK,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,PSMA4,EGFR,RASA1,HLA-B,FGFR2,PHLPP2,FGF18,ITPR1,ARRB1,GRIN2D,JAK3 |
| 9.355e-06 | -11.58 | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | MSigDB lists | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | 66 | 24 | 17758 | 2588 |
PVRL4,GCA,COL9A3,CD55,ATP8A1,DGKA,JAG2,UNC45B,FAS,MMP15,ARHGAP24,PITX2,RB1,FGF18,DAPK1,PRKG1,TNFRSF18,DIXDC1,IGFBP2,ESPN,NOTCH3,SLC27A3,ABCA1,HOXC13 |
| 9.447e-06 | -11.57 | diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | diffuse_large_B_cell_lymphoma | 4353 | 721 | 17775 | 2585 |
DOC2A,TRIM24,IBTK,AASS,SLC25A13,DNAJC3,RET,CACNA2D2,NRG2,MORF4L2,SNX9,BARD1,GRM5,CALM2,CDKN2C,DAPK2,PSMD1,ARHGAP42,DNAH6,CYP2S1,RDH14,DNM2,PIK3CD,TIAM1,IL10RB,CPE,ERAP2,NEK4,SPEF2,TNIP1,SH3BGRL,CDA,TFAP2C,PRKAR2B,LOXL2,PPP1R14C,MYOM1,GINS4,COL12A1,BOLA3,PLCG1,WDR11,GRID2IP,DNM1L,LIMK1,CELF5,MYLK,NOD2,HDAC1,ARF6,STARD13,PDPR,GAB1,ZNF720,FAM169A,ITGA6,SOX9,SLC36A4,GPSM2,MERTK,ATG4A,MARCH8,FRY,FAM189A1,CD22,RIMS3,ZIC5,FBXO7,MAP3K9,SLAIN2,CADPS2,USP38,STT3B,NCAM1,MOXD1,MYLIP,DGKG,NUP85,MCCC2,EPHX1,KIF20A,SALL4,STAT4,MYBL2,KIF20B,DPYSL4,PCTP,DCP2,CYB5A,STK17A,DHX32,PTPRF,CACHD1,NCOA3,NAAA,HTT,ITPR1,DGAT2,DYSF,XDH,EGLN1,DOCK9,WDR63,GRHL2,PAPSS2,ACTR8,RHBDL3,APOO,ETNK1,TESK2,PKP2,FAM91A1,APC2,REPS1,KIAA1147,ZNF385B,APPBP2,CDS1,UHRF1BP1L,MUC16,RNF220,SCNN1A,CDH1,SP100,RASGEF1A,RNF169,SCN3A,MX1,AGPS,PTPN9,SYNE2,VPS4B,CDCA2,RAB38,TANC1,IRS2,SPIN3,CCNB3,SHROOM3,CDK19,WFS1,SIPA1L1,WWTR1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,FAM189A2,PARP14,BACE1,HABP4,SDC4,ANO9,PKN1,PLPPR4,ETS1,SLC25A43,SRPX2,ICAM1,NEO1,PDIA4,ZFX,PDCD10,SLC27A6,ANKS1B,CTSC,FAM20B,KLC3,FAM102A,WWP1,NPTXR,SGCB,AMOTL2,ADAMTS2,LCA5,PLSCR1,CTNNAL1,FAM160A1,TACC1,RAPGEF2,PIK3R1,EIF5A2,CXorf57,PLEKHA7,UBE2A,RAB3IP,SNTB1,ABLIM2,TXK,CNTNAP1,BTG1,PROM1,RPL12,PLOD2,CCDC6,SYT7,NR1D2,ZFP30,PPM1H,ITGAV,FHL1,DCBLD1,TLL2,BCAM,AGRN,EPAS1,EPHA4,CUL4B,LMCD1,ITPR2,SDC1,PIGL,SPTB,BTG3,NUP210,TM9SF2,CTNNB1,P4HB,SHC3,PAPSS1,MITF,DUSP10,RGS5,ANO4,TLN2,MYBL1,TRAM1,S100A13,SMAGP,ZNF462,THRB,MCTP1,PTPN18,KCNIP3,CELSR2,C12orf65,ERP44,ANLN,IDH1,DPYSL3,TRAM2,KLF12,MAP2,RAB11FIP1,PIK3C2B,EPB41L4A,GLCCI1,TC2N,HS6ST3,RRAGD,FXYD3,RAB6A,CNTNAP2,NCKAP1,B4GALT4,DOCK11,PGAP1,SSX2IP,MYO5C,TNS3,RB1,VASP,IGF1R,FRAS1,MDFIC,PIM1,WNT3A,NTN1,ABCC1,CHSY3,WDR72,PCDH1,CORO2A,SPATA13,IFIT3,BCL2L13,UNC45B,ANKRD29,PRX,P4HA3,PLD1,SEMA3A,USP43,KCNAB3,CTDSPL,TMX4,XYLT1,TP53,RHPN2,ERBB2,P2RX7,STIL,PER2,CDK14,TTC21B,TACC2,LMO4,PPME1,PLCG2,BCL6,CDH3,GLB1L2,NOTCH3,FAR1,SULF2,CLCN3,TMTC1,MBP,AKT1,DAG1,IDE,ABHD12,PTK7,ADAMTS14,MAOA,CHMP4B,EFNA5,ARHGAP4,NDST3,CMTM4,FAM134B,BIN1,GOLIM4,CDH22,TRAPPC10,SCD5,GNAL,MCTP2,GABRG2,JAG2,DSE,SLC9A2,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,FOXP2,CEP97,MAGEE1,UBE2J1,SGK1,BUB1,FAM134C,IGDCC4,NFE2L3,DLGAP1,RHOA,PSMB4,NR3C1,MAML2,PELI3,FNDC3A,TXNDC11,DGKE,CD83,BCL10,DDAH1,BANK1,SERPINA1,FAT4,SCG2,ZNF214,SH3BGRL2,TBC1D4,PTGES,HIPK3,ARHGEF4,FAM171B,SLC35D2,PPP4R4,HSPG2,LGR4,VANGL1,FAM129B,ATP8A1,GATA3,PSME1,PDGFRL,VASH1,SLC20A1,TYMP,SESN3,ZNF823,ELMO2,STIM1,SERINC2,PIK3CA,STEAP2,ATRNL1,RCAN3,ORAI2,LOC81691,SNTB2,CASP9,HSPA12A,CDYL,KIF13A,GALNT7,CCNF,LDB2,ANKRD10,BMP1,PRDM5,EIF4EBP2,NFKBIZ,TANC2,CCDC97,DDX58,KLF2,CDK17,FRMD4A,CDKN1C,TBC1D1,C6orf106,NOTCH2,SLC1A3,APBA1,TNFRSF19,TSPAN7,PRRG4,SH3RF2,CALR,DOPEY2,ITGA3,RALGPS2,LYPD3,PIK3AP1,BDH1,MSH2,RUNDC3B,PRKG1,SORL1,OSTF1,CD70,CACNA1D,PIKFYVE,KCTD3,GPR161,RIMS2,TRAK2,FAM69A,EPB41L5,GFPT1,FADS2,GCC2,CEP89,TBC1D8B,LPGAT1,PTPRH,DCHS1,WHSC1,PYGL,ANTXR1,NFIB,RASA1,STX3,PDE11A,FAS,DGKH,NT5C2,PRKAG2,PLEKHH2,TJP3,FAAH,ISM1,PELI2,C1orf21,PIAS2,APPL2,SFMBT1,PCDH19,PER3,MAP3K5,HOOK1,IFIH1,EHD1,IRF1,FRMPD3,PLA2G4A,SPRED1,SLC2A4,DLGAP5,S100A11,ST14,IQGAP1,RPS6KA1,CCDC110,ATP2C2,FLT3,NUDT12,MNS1,CYP39A1,ZFYVE9,EPM2A,NOV,IFIT1,EPHB4,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,PANK1,UTRN,TMEM144,PRKCQ,CBL,SP4,PRDM11,NIN,EPHA10,PPP2R5A,ZNF704,NRG1,MLKL,NR3C2,COBL,MAMDC2,DENND5B,MRPS9,OTUD5,WASF3,ATP9A,CENPI,EPS8,PBX3,PNPLA5,LGALS3BP,WWP2,RNF128,OXCT1,PTEN,FUT8,ERBB3,CNOT6L,NCOA2,MSH6,FARP2,PCCB,RASGRF1,PDGFC,ARHGEF28,ARAP2,CASK,PAPD7,ZC3H11A,DENND1B,DIAPH2,LRRC1,GRTP1,ARSK,KIF11,GPLD1,RCBTB2,TBX18,RIN3,ABCB1,PGM2L1,GRIN2D,ETAA1,ARSB,ESPL1,OCLN,USP16,JARID2,EXPH5,LTBP1,FAF2,DNER,TMC1,TRIM68,SH3KBP1,NKAIN3,ZFYVE16,ARHGEF10L,SIPA1L2,HSF2,CDKL5,ARHGEF37,TSPAN6,IMPAD1,ANKFN1,DLG1,POF1B,TRPC1,SUN3,RAB20,ASH2L,NFU1,CTTN,ARNT2,PTPRE,MYRIP,BTBD3,OLFML2A,TRIM8,ASXL1,SYNE3,ACBD3,ITCH,RNF165,RGAG1,ROR1,EDNRA,MAN2A2,TDRD7,IARS2,RBM43,PPP2R5D,PCSK5,NR2C2,ARAP3,PPP1R12A,ABCG2,SAMD9,PHLPP1,ADAMTSL4,QSOX2,ZNF432,OTUD1,FAM20C,COL6A1,FNIP1,LIMCH1,KNTC1,HLA-C,NCEH1,SLC12A2,GAD1,ETV7,SNED1,ELK3,PDE5A,KIAA1109,HEATR5A,NUBP1,PDIK1L,EGFR,XKRX,ONECUT1,TMEM30A,UTP14C,NFKBIA,NXPH4,ALPK3,KIF12,JAK3,KLF7,LMO7,NCKAP5,ZSWIM5,PSME2,PDIA5,MRAS,MICALL2,MXD1,ZNF687,FRYL,SMO,RPN2,EPB41L4B,NFKB2,PDIA6,SOAT1,MAP3K3,ZNF525,TMTC2,DUSP4,DOCK5,STAT6,TLE1,VSIG10,SPTBN5,PLXND1,AKNA,LNP1,LIFR,SORT1,ARHGEF11,SH3D19,TGFBR1,TRMT2B,FAM167A,XPR1,TMEM63A,KIF5B,IL17RB,SNX13,CARD8,ADRBK1,MLPH,BMP7,TOX2,RRBP1,KIAA0319,H2AFY,BRD7,MYO5A,PGM1,SYPL1,ADAM17,ASPM,MBNL3,OGDHL,TTC7A,MAP1B,KLHL2,HLA-B,SWAP70,TRIM69,RND3,FIBCD1,CSGALNACT1,UBE2D2,AHR,RAB3IL1,NGEF,ZNF596 |
| 9.560e-06 | -11.56 | ENK_UV_RESPONSE_KERATINOCYTE_DN | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_DN | 481 | 105 | 17758 | 2588 |
GAS2L1,RGS20,ARFGEF1,CUL1,KTN1,CDK14,CD46,ENTPD4,SP100,TM9SF2,BCL6,CDKN1B,GOT1,ASH2L,RP2,IFIT1,IL10RB,UPF3A,EBAG9,LAMP3,LAMP2,CPD,SEC23A,SMARCA2,CELSR2,AGPS,SNTB2,ACBD3,BNIP3L,SLC11A2,DUSP4,H2AFV,SLC25A5,ZFAND5,ACYP1,SLC9A6,HOXA9,WWTR1,MAOA,NRG1,PRKAR1A,SERPINE2,PEX6,GCAT,ARHGEF7,GNE,JAG2,DHRS3,LBR,DUSP5,FZD6,TFAP4,TOP2A,RB1,DOPEY2,RRBP1,GTF2F2,PRKCI,SORL1,USP1,KLF9,NPTN,RPGR,SLC35A1,MYO5A,TMX1,IGSF3,SNX7,SYPL1,HES1,ZWINT,PLSCR1,PAPD7,TACC1,CTNNAL1,MICB,TCFL5,YES1,FOS,ZDHHC3,STEAP1,RASA1,NMT2,USP6,BCAR3,CNOT2,NCOA3,ACADSB,RCBTB2,H1F0,CCDC6,RND3,NMI,ERAP1,PKD2,MDH1,ACADM,ATP1B3,MAP3K5,UBE2C,CTBP1,AFAP1,COL16A1,KLF7,ARHGEF4 |
| 9.588e-06 | -11.55 | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | MSigDB lists | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | 110 | 34 | 17758 | 2588 |
GCLM,ILDR1,SPC25,DLGAP5,SOD2,NUF2,CCNB1,IER3,CALR,PCNA,CYR61,ALG13,PCYOX1,NEK2,BUB1,TACSTD2,PDGFC,CTNNAL1,ASPM,PBK,EIF5A2,CDC20,MYBL2,TEP1,PIF1,FOS,GALNT3,LIMK1,CORO1C,TBX18,FAM3C,WWTR1,AURKA,SPCS3 |
| 9.682e-06 | -11.55 | TCGA_GLIOBLASTOMA_MUTATED | MSigDB lists | TCGA_GLIOBLASTOMA_MUTATED | 8 | 7 | 17758 | 2588 |
ERBB2,RB1,PTEN,EGFR,PIK3R1,PIK3CA,TP53 |
| 9.685e-06 | -11.54 | GSE360_CTRL_VS_T_GONDII_DC_UP | MSigDB lists | GSE360_CTRL_VS_T_GONDII_DC_UP | 197 | 52 | 17758 | 2588 |
PINK1,ZCCHC24,INPP5D,ETV5,HEXB,KCTD12,TGOLN2,ITPR2,MGST2,CRABP2,TRIB2,VASH1,SRPX2,KTN1,GBX2,PDIA4,CES2,METTL7A,MEGF8,ATP5H,PLCG2,FABP6,KCNS3,BAX,SORL1,H2AFY,AHCY,PIKFYVE,S100A13,FAM134C,CTNNAL1,S100A4,CORO2A,ESYT1,IDH1,USP6,FUCA1,ALDH3B1,STX10,RCBTB2,RAB11FIP2,SCG2,PRCP,SLC9A6,PLA2G15,TCEAL4,PNPLA6,TTC9,LTA4H,SEMA3A,NRGN,PTGES |
| 9.685e-06 | -11.54 | GSE24142_DN2_VS_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_UP | 197 | 52 | 17758 | 2588 |
BIN1,DYRK3,SLC25A24,MRC2,ARMCX3,FAM101B,ECI1,ITGA2B,IER3,IL17RB,ADD3,FUT8,CD9,STEAP3,PIM1,TAGLN2,PHKA2,PTPRE,TTPA,GM2A,CKAP4,S100A6,IGDCC4,GCNT1,TUBA4A,P2RX4,TMCC2,PLSCR1,CTNNAL1,S100A4,LITAF,CCDC34,PYGL,MAP3K6,RHOB,ATP13A2,CMTM7,RASGRP2,PI4K2B,ATP1A1,SH2D3C,APPL2,RAB31,TLE1,EGFL7,ATP1B3,LRRK1,TMEM159,CMPK2,SERPINB1,NRGN,CSRP2 |
| 9.685e-06 | -11.54 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | 197 | 52 | 17758 | 2588 |
SUN1,CD99,ACVR1,TCF25,TMEM184B,GPR107,AASS,DAP,TP53,ERBB2,BCL2L1,VASH1,SEPP1,PDIA4,RABGGTA,TMEM63A,FLII,RAC2,CDK16,SH3BP1,FBXO7,TBCD,CD9,LGMN,FLOT2,PTPRE,SMYD5,CTDSP2,P2RX4,RHOA,TESK1,DCHS1,UTRN,CR2,KIAA1109,RNF113A,C15orf39,IDH1,MDK,ALDH3B1,RCBTB2,PPP2R4,INPP4B,IRF7,NRG1,ZMIZ1,ARSB,LTA4H,SLC31A2,LIFR,L1CAM,CD33 |
| 9.688e-06 | -11.54 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 182 | 49 | 17758 | 2588 |
CD99,KLF2,TXN,IL15RA,PPP1R12A,DNAJC3,NDRG1,ITGA6,TGFBR1,DNAJB9,HDAC9,TMEM63A,IL17RB,CAPN2,MARCH8,ATP6V0B,FAM46A,SGK3,PCYOX1,WWP1,RTKN2,ESPN,SELK,FAR2,MYBL1,TRAM1,ETV7,TMBIM1,SMAGP,KIAA0040,ACVR1C,LYRM1,SYNE2,BLVRA,DAG1,FAS,OPTN,IRS2,HS6ST1,RCBTB2,WDR19,TDRD7,NFKBIZ,SERPINI1,F2RL1,NR3C2,AHR,NIPA1,SNX30 |
| 9.713e-06 | -11.54 | STK33_NOMO_UP | MSigDB lists | STK33_NOMO_UP | 269 | 66 | 17758 | 2588 |
ELK4,SPRED1,ACVR1,EPAS1,FAM199X,DDIT4L,RASGRP3,FAM198B,EGR3,PHLDA1,IER3,SIPA1L2,BTG3,IL6ST,ZFP36,BCL6,ANKRD12,ARNT2,DOCK4,OSTM1,COQ10B,KDELR3,SLC11A2,PTGFRN,STK17B,ULK2,UEVLD,LIMK1,FAM114A1,RNASEL,ST3GAL1,ABCA1,MAFF,CPEB4,NUAK1,SDC4,ARL4C,FAM134A,GDF15,MERTK,DUSP5,ICAM1,SGPL1,OTUD1,DAPK1,SGK1,NCEH1,KCTD3,DUSP1,GFPT1,TGIF1,DENND1B,MGAT4B,KBTBD8,YES1,FNDC3A,FOS,RHOB,IL1R1,NR1D2,SCG2,SEMA4D,RND3,WDR19,APPL2,TMEM159 |
| 9.715e-06 | -11.54 | GSE20715_0H_VS_6H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_6H_OZONE_LUNG_UP | 192 | 51 | 17758 | 2588 |
TTC8,PARP12,ST13,VANGL1,PPFIBP2,PKP2,FAM198B,GRK6,GPSM2,TNFRSF19,PDGFB,ANO1,SH3KBP1,LMNA,CDKN2C,SLC25A45,MDM1,DACT1,SIVA1,AKR1B1,TAGLN2,RCAN3,MAPK7,MYLIP,DGKG,S100A13,CAMK2G,SEC61B,IFITM3,SEPT6,MPP1,BNIP3L,EPHA1,RAB38,TRIM7,AMZ2,DCTN6,CNOT2,TRIM47,GPRC5B,SEMA4D,CSF1,CSNK1G1,FGF18,PRKCDBP,MRPS28,EFNA1,UNC5B,FZD5,SERPINB1,GAB1 |
| 9.715e-06 | -11.54 | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | 192 | 51 | 17758 | 2588 |
CDK17,NFKBIE,SDC4,OSGIN2,GDF15,CCNL1,PHLDA1,TNFSF9,DUSP5,IER3,RPS6KA2,SETDB2,CENPJ,ZFP36,BCL6,SGK1,RAB20,PIM1,CITED2,TIPARP,STK35,CKS2,DUSP1,TGIF1,BAG4,PLSCR1,BCL9,USP18,PTGER4,DUSP4,ANLN,ZFAND5,RNF19B,FOS,C18orf8,SOCS3,PTGS2,RND3,PLK2,PHLPP2,NFKBIA,SLC2A6,FAM83D,ARFGAP3,NFKBIZ,ST3GAL1,MAFF,TOB1,IRF1,EHD1,DRD1 |
| 9.715e-06 | -11.54 | GSE3982_NKCELL_VS_TH2_DN | MSigDB lists | GSE3982_NKCELL_VS_TH2_DN | 192 | 51 | 17758 | 2588 |
PLA2G4A,ST13,EPAS1,CKAP2,CENPI,PTTG1,ABCG2,KIF2C,STIL,PGAP1,ICAM1,FANCI,UHRF1BP1L,TNS3,PCNA,CCNA2,RALB,MSH2,CKS1B,H2AFY,TSPAN13,MANF,CKS2,NFE2L3,TDP1,SEC61B,CENPA,KIF20A,EZR,NUSAP1,KIF20B,DUSP4,GTF2A2,KIF11,GINS4,FRMD4B,SFXN1,PTGS2,SLCO4A1,PRDX3,PRPS2,INPP4B,AURKA,XRCC3,AKIP1,NCAPG2,TBC1D4,CCNB2,ESPL1,ACOT7,FAM134B |
| 9.715e-06 | -11.54 | CELL_CYCLE_PROCESS | MSigDB lists | CELL_CYCLE_PROCESS | 192 | 51 | 17758 | 2588 |
ACVR1,USH1C,DLGAP5,CDKN1C,CIT,NDC80,CUL1,KIF23,RACGAP1,KIF2C,CNTROB,SAC3D1,CKAP5,CDKN2C,NPM2,RB1,CCNA2,PRC1,NEK2,TUBG1,CDKN1B,KIF22,BUB1,KNTC1,GFI1,CDKN2D,HSPA2,MPHOSPH9,SMC4,REC8,PLK1,SUN2,ZWINT,PAPD7,NUSAP1,RAD17,PKMYT1,ANLN,CDC25C,KIF11,CDCA5,MAP3K11,E2F1,ARAP1,AURKA,KPNA2,CENPE,NDE1,UBE2C,ESPL1,RAD21 |
| 9.716e-06 | -11.54 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | 187 | 50 | 17758 | 2588 |
GRN,SLC35D2,TUBB4B,GGA1,CD82,NANS,M6PR,CAPN2,TNS3,TYMP,TM9SF2,CTSC,KCNN4,LMO4,BHLHE41,FUT8,PAPSS1,CAPG,FAM102A,CD70,MDFIC,ITM2C,CKAP4,PPIF,ING1,PTPN18,SEC61B,S100A4,HTATIP2,SGPP1,OPTN,SOCS3,HLA-B,TRAM2,ATP1A1,LDLRAP1,SLC25A4,WIPI1,CSGALNACT1,SPAG7,RAB31,CAB39,CTSA,KPNA2,ZMIZ1,TMEM14A,IFI6,NRBP1,EHD1,EGLN1 |
| 9.925e-06 | -11.52 | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN | 487 | 106 | 17758 | 2588 |
CCNI,ST13,SSH1,TP53,GATA3,DNAJB11,BCL2L1,CAMK1D,C1orf116,APPBP2,RAD23A,CDK14,CALM2,EPCAM,SIPA1L2,SESN3,ST5,P4HB,FRYL,DPYSL2,KLF3,MANF,PPP1CA,SLC39A10,TIAM1,FGFR1OP2,ZNF462,SMARCA2,TRIM8,TIMP2,SERTAD3,ATP1B1,LDB2,PTGFRN,NFIX,ZNF628,TBC1D17,PEX5,MPRIP,PTPRJ,DDOST,KCNK1,PTK7,DOLPP1,TRIOBP,ZNF704,ADIPOR1,SP6,ANXA9,SYT13,CHPT1,ISOC1,CBX4,GRN,IER5L,CD99,KLF2,GOLIM4,HSP90B1,ITGA6,SOX9,CALM3,NDUFA4,ZNF219,SPR,DHRS3,FBLN1,ETS1,PDIA4,CALR,DAZAP1,OXCT1,IGF1R,MGAT1,GATA2,FRAS1,CALD1,PIKFYVE,MYLIP,PHKG2,TMED2,MDFI,GCC2,ADAM17,BCL9,CALM1,RC3H2,FURIN,LITAF,HMG20B,FAM109A,BSDC1,RHOB,BTG1,SERTAD2,CASP7,FAT4,SMTNL2,DGCR2,RND3,KBTBD2,NR4A2,PLIN3,CTBP1,SRSF9,JARID2 |
| 9.978e-06 | -11.52 | regulation of cell projection organization | biological process | GO:0031344 | 509 | 112 | 16441 | 2455 |
FOXO6,SSH1,AGRN,EPHA4,RET,P2RX7,GATA3,PLXNA1,CAMK1D,MNS1,EPS8L2,NCS1,CDKL5,DPYSL2,DNM2,DAB2IP,ESPN,TACSTD2,SEMA3G,CTTN,PACSIN1,TIAM1,TBC1D10B,SEMA3B,SSH3,AKT1,DMTN,CDC20,EZR,KLK6,PRKCQ,ULK2,ARHGAP35,DPYSL3,TBC1D17,FYN,GPRC5B,BHLHB9,PLK2,CORO1C,PTK7,LIMK1,SIPA1L1,FAM110C,KLF5,EFNA5,RAB29,NRG1,PLXND1,ITPKA,ARF6,RAP1GAP,F2RL1,LZTS1,COBL,GRN,SEMA6B,PIFO,SERPINE2,TBC1D1,CIT,ARHGEF7,LRP4,TGFBR1,NCKAP1,CRABP2,ICAM1,CORO1B,SPP1,RAC2,ITGA3,PTEN,KNDC1,MEGF8,BMP7,KIF13B,KIAA0319,PRKCI,ATP8B1,TNFRSF12A,NPTN,NTN1,WNT3A,GFI1,ITM2C,SPRY2,FAM134C,CCDC88A,RIMS2,RHOA,RAPGEF2,GRIN1,PLS1,ILK,CDK5R1,MAP1B,ARHGAP24,PTPRF,SEMA4D,HTT,TMEM30A,ARAP1,PLD1,EFNA1,ARPC2,ARSB,SEMA3A,SHOX2,L1CAM,ADAMTS16,NGEF,PROM2 |
| 9.986e-06 | -11.51 | regulation of cytoskeleton organization | biological process | GO:0051493 | 400 | 92 | 16441 | 2455 |
GAS2L1,NF2,SSH1,ADD1,ARFGEF1,P2RX7,F11R,CCNB1,HDAC6,APC2,SPTB,PICK1,PDGFA,CTNNB1,CTGF,DLG1,CAPG,PLK4,CDKN1B,ESPN,DIXDC1,TACSTD2,CTTN,NEB,PLK1,CAMSAP3,SSH3,PSRC1,BAG4,CAPN6,DMTN,DSTN,PTGER4,VPS4B,EZR,PRKCQ,AURKB,CCNF,MID1IP1,ARHGEF19,PLK2,LIMK1,TRIOBP,CHMP4B,XRCC3,EFNA5,SPTBN5,TMOD2,ARF6,GEN1,F2RL1,CKAP2,EPS8,SDC4,NES,SORBS3,RACGAP1,NCKAP1,ICAM1,CORO1B,CAPN2,VASP,CENPJ,TBCD,TUBGCP6,NEK2,SLAIN2,WNT3A,CCDC88A,RHOA,FMN1,PIK3R1,RGCC,STMN3,EPHA1,ILK,SKA1,BORA,KIF11,NUBP1,RASA1,CDK5R1,AP1AR,TSC1,PLEKHH2,SWAP70,CTSV,ARAP1,AURKA,ARPC2,SHROOM2,AFAP1 |
| 1.000e-05 | -11.51 | ST_GAQ_PATHWAY | MSigDB lists | ST_GAQ_PATHWAY | 28 | 14 | 17758 | 2588 |
PITX2,NFKBIE,ADRBK1,AKT1,NFKBIA,ITPR1,PLD2,ITPR2,PLD1,PHKA2,ITPKA,ITPR3,NFKB2,DAG1 |
| 1.000e-05 | -11.51 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | 238 | 60 | 17758 | 2588 |
CCNI,CASP3,TXN,PPP1R12A,TRIP10,SUZ12,SDC4,RASGRP3,IL13RA1,PLXNA1,CCNL1,C3orf18,DUSP5,SGPL1,LYPD3,DPYSL2,ZFP36,IL6ST,SORL1,TFG,EGLN3,SLC16A5,FAM69A,SEPHS1,LAMP3,GFPT1,FOXJ2,LITAF,RUNX3,RAB38,ZFAND5,MAP3K6,ADRBK2,STK17B,CYB5A,CD83,RASGRP2,OPTN,IL1R1,DUOX1,NCOA3,BTG1,JAK1,PVRL2,SPINT2,NETO2,NR4A3,RAB11FIP1,MAOA,NRG1,ATP1B3,LRRK1,RPL22,FZD5,NDE1,TRAF5,TBC1D4,F2RL1,HSPB1,ABCG1 |
| 1.008e-05 | -11.50 | regulation of response to stress | biological process | GO:0080134 | 1397 | 265 | 16441 | 2455 |
LAMP1,TXN,GRIK2,TRIM5,DNAJC3,XIAP,TAP1,CUL1,GATA3,PSME1,IL18,VASH1,ELMOD2,TP73,CALM2,ZYX,PHYHIP,SESN3,PSMD1,AP1M2,CTGF,APOBEC3G,NEK4,TNIP1,PBK,CASP9,BNIP3L,SLC35C1,F12,MYOM1,ABR,DNM1L,ANKRD6,TRAF3IP1,MYLK,NOD2,MAP3K11,MAPK13,HSPB1,F2RL1,GAB1,LZTS1,DDX58,SCOC,NUAK1,HLA-E,SLC1A3,MECOM,ZCCHC17,PIK3AP1,FAM13B,MAP3K9,PRKG1,USP1,TNFRSF12A,ALPK1,PIKFYVE,MAPK7,NUP85,QSOX1,KLK5,MAPKAPK3,MICB,CALM1,ANO6,SHARPIN,PIP4K2C,WHSC1,CALCRL,ELK1,PSMA4,PTPRF,IL1R1,PELI2,ITPR1,OSMR,MDH1,STK39,KLK7,MAP3K5,IFIH1,TRPC3,NUP58,RPS6KA3,TMEM173,XDH,IRF1,SPRED1,NLRX1,RPS6KA1,BCL2L1,PRKACA,EPM2A,CD46,NOV,FAM46A,RALB,DACT1,DAB2IP,IFIT1,LGMN,CDKN2D,RNF169,ENPP4,RIPK2,FZD4,DMTN,PRKCQ,ATP1B1,ITPR3,FZD7,FYN,JAK1,CDK19,STK26,WFS1,KIAA1804,STAT1,HSP90B1,NKX3-1,TAOK2,TRAF2,HERC5,PKN1,ETS1,GSTP1,FGF19,HLA-A,PDCD10,IRAK1,PTEN,BAX,TMBIM6,MAPK11,MAP3K7,CNPY3,PARP9,CASK,PLSCR1,PIK3R1,VAMP3,FOS,TXK,NR1D2,SLC35B3,NR4A3,ERAP1,GPER1,HMGA1,FZD5,NUP37,UNC93B1,EPHA4,LMCD1,ARFGEF1,ITPR2,HDAC6,ERP29,MAP1LC3B,PDGFB,NUP210,RPS6KA2,PCNA,P4HB,TSPAN6,IL6ST,PSMC2,DLG1,DUSP10,CTTN,SCARA3,RASGRP1,SMAGP,SOD1,CD55,USP18,ITCH,EZR,SESN1,KDM4D,HPSE,GPRC5B,POMT1,PPP2R5D,PSMC1,TC2N,PRKAA2,SERPINE2,UBASH3B,PSMD7,CALM3,TEC,PHLPP1,BMP2,SPP1,IGF1R,PAK2,MDFIC,PSMA5,MDFI,EIF2AK1,EGFR,MAPKAPK2,FECH,NUDT16,PVRL2,PLPP3,NFKBIA,NLRC5,YOD1,IL15,FOXM1,PSME2,SOD2,TP53,SLC7A2,BCAP31,IER3,PDGFA,PLCG2,BCL6,TWIST1,NFKB2,F2R,DVL2,SIRT1,MAP3K3,BAG4,ERLEC1,AKT1,FIGNL1,PTGER4,DUSP4,MAP3K6,CASP4,SOCS3,PTGS2,PSMD3,IRF7,CHMP4B,PINK1,TAB3,CTSB,SERPINB9,PSMD10,CD109,ADORA1,BMP7,UBE2J1,IL17RA,SYK,CAMK2G,FBLN5,PSMB4,PLAUR,PPARA,FXR2,MAPK8IP1,BCL10,CTSL,HLA-B,NMI,UBE2D2,NDFIP1,HIPK3 |
| 1.011e-05 | -11.50 | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | MSigDB lists | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | 572 | 121 | 17758 | 2588 |
SPRED1,TRIM2,NF2,TRIP10,TSC22D3,RET,KLC2,WDTC1,ABCG4,UBE2Q1,MRAS,SLC7A2,FAM91A1,CARD10,NCS1,SLC25A35,WEE1,SIPA1L2,ZYX,TGFBR3,ELMO2,LMAN2L,VAT1,SNX16,ACSL4,EPB41L4B,PDIA6,SMYD5,TRAM1,CPD,MAP3K3,PCGF5,TAF5,KREMEN2,CAPN6,SNTB2,SESN1,COL12A1,KDSR,CDCA4,PEX5,DOLPP1,SLC9A6,MYLK,LRIG1,CAB39,ZC3H12B,PIEZO1,SPRY4,CHPT1,ISOC1,PDPR,CBX4,CDS2,CDK17,SCOC,LRRFIP2,TAB3,DCAF7,BACE1,FAM134A,PBX3,KIF23,FAM81A,SIX4,NRP2,TFAP4,IRF2BPL,KIF5B,E2F7,TMEM87B,MGAT4A,BHLHE41,KCNN4,TFAP2A,UBE2J1,SGK1,WWP1,PIM1,C8orf58,C10orf54,WNT3A,SLC12A2,MOB4,SYPL1,PHF20L1,MMD,PIK3R1,GRIN1,ZKSCAN2,LITAF,FURIN,AK4,STRADB,FAM133B,EPHA1,SRSF5,PDIK1L,SFXN5,CDK5R1,SLC4A4,RAB11FIP2,CCDC6,PHLPP2,KBTBD2,SETD3,CSNK1G1,AMMECR1,C1orf21,RAP2C,PLA2G15,ITPR1,NR4A3,PITPNA,SH3BGRL2,YOD1,HMGA1,ARHGEF9,CPEB2,RPS6KA3,DRD1 |
| 1.015e-05 | -11.50 | endoplasmic reticulum lumen | cellular component | GO:0005788 | 201 | 53 | 17570 | 2579 |
COL9A3,HSP90B1,BACE1,P3H2,CERCAM,DNAJC3,PDIA5,PDIA3,COL18A1,DNAJB11,CTSZ,COL4A5,PDGFB,FLT3,ADAMTSL4,ERP29,DNAJB9,PDIA4,PDGFA,RCN1,CALR,CES2,CTSC,ARSG,P4HB,COL6A1,MYDGF,MINPP1,WNT3A,CNPY3,PDIA6,CRTAP,ERAP2,PDGFC,ERLEC1,COL6A2,TMEM43,PLAUR,ERO1A,ERP44,COL7A1,ARSK,COL12A1,DNAJC10,PTGS2,SERPINA1,COL13A1,P4HA2,P4HA3,ERAP1,ARSB,COL16A1,KDELC2 |
| 1.026e-05 | -11.49 | microtubule organizing center | cellular component | GO:0005815 | 608 | 128 | 17570 | 2579 |
NDRG2,CNTROB,SYTL4,CCNB1,PHF1,CALM2,PCNA,CTNNB1,CNTRL,CEP78,DDHD2,CAPG,DNM2,ABCA2,TUBG1,HYLS1,RP2,ODF2L,CCDC38,PLK1,PCGF5,FOPNL,UXT,EZR,CKAP2L,PRKAR2B,KIF13A,AURKB,CCNF,CDK1,DZIP1L,NEIL1,CAMK2N2,PLK2,TRAF3IP1,FAM110C,MAP3K11,TRAF5,PIFO,PPP1R12A,CALM3,KIF23,TXNDC9,SSX2IP,FLII,FRY,NEK2,SLAIN2,LRIF1,MPHOSPH9,CEP89,B9D2,CALM1,KIF20B,NUBP1,MAPKAPK2,HTT,AURKA,MDH1,NDE1,CFAP20,CCNB2,DYNLRB1,SORBS1,UPF3B,DLGAP5,CEP70,NDRG1,ACTR8,ZMYND10,BCL2L1,STIL,PRKACA,LRRC45,TACC2,PLK4,PDE4D,SNX10,ZNF365,CAMSAP3,AKT1,CDC20,CCSAP,VPS4B,CEP162,NIN,STK26,TRIOBP,RGS14,GEN1,SGOL1,TTC8,MZT1,CKAP2,POC1B,RASSF7,ERCC6L,FLOT1,SPDL1,IFT27,SAC3D1,CKAP5,CCDC92,TOP2A,KIF5B,TBC1D31,CEP97,MZT2A,PHF7,CENPJ,TUBGCP6,TFAP2A,RPGR,LCA5,TACC1,RGCC,PLEKHA7,YES1,RAB3IP,BBS2,DCTN6,PKD2,SSNA1,PPP2R3C,CEP41,WDR62,ESPL1,DIS3L |
| 1.029e-05 | -11.48 | ITPR1 (inositol 1,4,5-trisphosphate receptor, type 1) | protein interactions | 3708 | 43 | 19 | 16036 | 2547 |
UFD1L,RHOA,AKT1,AMFR,CALM1,ERP44,ITPR3,CCNB1,PRKACA,CA8,CDK1,VCP,FYN,BANK1,CABP1,PRKG1,TRPC1,TRPC3,STARD13 |
| 1.051e-05 | -11.46 | REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | REGULATION_OF_KINASE_ACTIVITY | 153 | 43 | 17758 | 2588 |
CCNE2,SPRED1,TAOK2,CDKN1C,TRAF2,ERBB2,HERC5,PKN1,TRIB2,CARD10,PICK1,CDKN2C,DIRAS3,CCND1,RB1,IRAK1,PTEN,RGS3,PAK2,MAP3K9,CKS1B,MDFIC,HEXIM2,MAP3K7,CDKN2D,CCDC88A,MDFI,CKS2,SOD1,STRADB,PKMYT1,CDC25C,MAP3K6,CDK5R1,EGFR,CDK5RAP1,RBL1,MADD,MAP3K11,KIAA1804,MAP3K5,CD81,HIPK3 |
| 1.098e-05 | -11.42 | GSE25087_FETAL_VS_ADULT_TREG_DN | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_DN | 163 | 45 | 17758 | 2588 |
HECA,ENO2,PPP1R2,AASS,UBASH3B,BACE1,MORC4,ASAH1,ANKS1B,PAIP2B,SLC16A6,SLC46A1,RUNDC3B,FXYD5,CDKN1B,SORL1,KLF9,SEMA3G,LRP11,CNPY3,MYLIP,C9orf72,SIRT1,POU6F1,LONRF3,FZD4,OSTM1,LITAF,CXorf57,BCL2L13,TRIM7,DGKE,CDK5RAP1,IRS2,SLC25A4,KLF12,COQ10A,SEMA4D,NR1D2,DTX4,TTC39C,TOB1,ATMIN,DCBLD1,ABCG1 |
| 1.129e-05 | -11.39 | mitotic nuclear division | biological process | GO:0007067 | 353 | 83 | 16441 | 2455 |
SPC25,DLGAP5,ACTR8,PTTG1,NDC80,XIAP,NUF2,KIF2C,CCNB1,SNX9,CENPN,WEE1,CCNA2,SETDB2,KIF14,KIF22,PLK1,NEK4,PSRC1,PBK,CDC20,VPS4B,CDCA2,NUSAP1,AURKB,PKMYT1,CCNF,ANLN,CDC25C,CDK1,TRIOBP,CHMP4B,RGS14,SGOL1,REEP4,PPP2R2D,ZC3HC1,PPP1R12A,KLHL13,CIT,EPS8,ERCC6L,CDCA8,CDCA3,KIF23,RACGAP1,SPDL1,CKAP5,SAC3D1,RB1,PTEN,SNX18,TUBGCP6,NEK2,BUB1,KNTC1,SMC4,ZWINT,RHOA,CENPC,PAPD7,ASPM,MYBL2,KIF20B,KIF11,BORA,SKA1,FAM64A,PAPD5,CDCA5,FAM83D,AURKA,CENPE,GEM,NUP37,NDE1,NCAPG2,CCNB2,UBE2C,ESPL1,USP16,RAD21,FBXW5 |
| 1.132e-05 | -11.39 | ORGANELLE_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | ORGANELLE_ORGANIZATION_AND_BIOGENESIS | 466 | 102 | 17758 | 2588 |
CASP3,GAA,SORBS1,NF2,SSH1,HDAC11,NDC80,TP53,TESK2,MRAS,KIF2C,TAF6L,CNTROB,BCL2L1,HDAC6,AIFM2,ARHGEF10L,NPM2,TYMP,AP1M2,DLG1,CAPG,TUBG1,ATG4D,SIRT1,CLCN3,SOD1,MARK1,COG2,DSTN,UXT,TEP1,VPS4B,EZR,NUSAP1,ARHGDIB,PIF1,ANLN,OPTN,MID1IP1,SLC25A4,DNM1L,LIMK1,PEX2,MAP3K11,HDAC1,KPNA2,ARF6,ARHGAP4,ABCA1,FGD1,WASF3,LASP1,PACSIN2,ARAP3,TAOK2,PEX6,KIF23,RACGAP1,SORBS3,PLD2,APBA1,SAC3D1,RND1,ATG4A,CKAP5,TOP2A,KIF5B,DOPEY2,CENPJ,KIF13B,TUBGCP6,PRC1,BAX,MSH2,PRKG1,ALS2CL,CCDC88A,SMC4,REC8,NAGPA,SUN2,RHOA,ZWINT,PAPD7,BCAR1,KIF11,NUBP1,RASA1,TSC1,RND3,CDCA5,ARAP1,FGD6,CENPE,HMGA1,NDE1,ARSB,SHROOM2,IFI6,ESPL1,GOLGB1 |
| 1.134e-05 | -11.39 | Tyr_kinase_cat_dom | interpro domains | IPR020635 | 88 | 29 | 18293 | 2672 |
TNK1,EPHA4,RET,ERBB2,TEC,ROR1,YES1,EPHA1,FLT3,DDR1,MERTK,EGFR,TXK,EPHA10,INSR,FYN,JAK1,IGF1R,FGFR2,AXL,PTK7,RYK,KIAA1804,MAP3K11,MAP3K9,ERBB3,EPHB4,JAK3,SYK |
| 1.134e-05 | -11.39 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN | 178 | 48 | 17758 | 2588 |
DDX58,CCDC109B,IL15RA,PARP14,TRIM5,ARHGEF11,TAP1,UBE2Z,HERC5,GPR180,PDGFRL,SAMD9,OSR2,TMEM19,HERC6,PGAP1,LGALS3BP,DTX3L,FAM111A,CYP1A1,SP100,OAS3,ALPK1,ETV7,APOBEC3G,PARP9,MX1,CASK,PLSCR1,PAPD7,USP18,IFIT3,PSMA4,FAS,PTGS2,PI4K2B,C19orf66,PVRL2,TRIM69,SECTM1,STAT1,NFKBIZ,IRF7,CMPK2,IFIH1,SLC31A2,IFI6,CSRP2 |
| 1.136e-05 | -11.39 | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDM_UP | 193 | 51 | 17758 | 2588 |
GRN,MRPS9,TM2D2,TTC39B,CRYM,ST14,ARHGEF7,CUL4B,PTTG1,ARFGEF1,NOTCH2,CAMK1D,GPSM2,ERP29,SPSB1,TSPAN17,CMTM6,ICAM1,CCDC92,TFAP4,PCNA,OXCT1,IGSF9,CTSC,PLCG2,RANBP1,TPST1,CDKN1B,TMEM37,TFG,PLCB2,BTBD3,ODF2L,CTDSP2,PVRL4,GCA,USP18,HMG20B,ZFAND5,RNPEP,MAPK8IP1,NAAA,PLK2,CSF1,LIMK1,PPP2R4,SECTM1,HOXB13,LRRK1,RGS14,TOB1 |
| 1.139e-05 | -11.38 | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN | 188 | 50 | 17758 | 2588 |
PLA2G4A,PARP12,IL15RA,IL15,PSME2,HLA-E,HLA-F,TAP1,SELL,CUL1,UBE2Z,HERC5,PSME1,SEPT4,LGALS3BP,ICAM1,RCN1,RALB,AIM1,OAS3,PIM1,TLN2,NTN1,SNX10,APOBEC3G,ERAP2,TMX1,FAM69A,MX1,SLC37A1,LAP3,IFITM3,RAPGEF2,UBE2A,IFIT3,CD40,RNF19B,PSMA4,FAS,NMI,PRPS2,SECTM1,STAT1,TDRD7,NOD2,IRF7,IFIH1,APOL2,ISOC1,IRF1 |
| 1.142e-05 | -11.38 | BMI1_DN.V1_UP | MSigDB lists | BMI1_DN.V1_UP | 139 | 40 | 17758 | 2588 |
ANXA3,AGRN,VANGL1,CD82,TAP1,DHRS3,KCNC4,TNFSF9,SRPX2,NRP2,SIRPA,B4GALNT1,CCND1,NOV,ITGA3,ITGB8,TMEM62,FJX1,TMEM51,ACTA2,SEMA3G,MICB,FURIN,COL7A1,LHFPL2,CRISPLD2,LCP1,ATP13A2,MMP15,SLCO4A1,TIMP3,CTNS,COL13A1,CSF1,LRIG1,SLC2A6,PIEZO1,FZD5,ABCA1,COL16A1 |
| 1.161e-05 | -11.36 | CCNB1 (cyclin B1) | protein interactions | 891 | 90 | 31 | 16036 | 2547 |
GAS2L1,PLK1,SIRT1,RUNX2,FOXM1,RALBP1,PBK,CDC20,NDC80,HERC5,PKMYT1,CCNF,CCNB1,CDC25C,CDK1,VCP,TP73,RB1,TSC1,PCNA,ITPR1,UBE2D2,PRC1,PPP1CB,CKS1B,CDKN1B,PPP1CA,CCNB2,ESPL1,ZC3HC1,CKS2 |
| 1.163e-05 | -11.36 | vacuolar part | cellular component | GO:0044437 | 397 | 90 | 17570 | 2579 |
LAMP1,GAA,AGRN,HSPG2,SLC2A8,HEXB,SDC1,MAP1LC3B,GNB2,ABCD4,DAPK2,NAPG,ATP6V0B,PQLC2,AP1M2,ENTPD4,RDH14,ABCA2,RPN2,ECE1,MARCH2,TSPAN1,LGMN,TMEM9,TMBIM1,GM2A,LAMP3,LAMP2,VPS11,EVA1A,OSTM1,AP5M1,SLC11A2,SLC17A5,TCN2,RHEB,GABARAPL1,ATP13A2,ENPP1,HPSE,WDR11,WIPI1,GLA,RRAGD,STARD3NL,MAN2B2,SORT1,CD63,TMEM55B,CTSB,SDC4,FLOT1,ASAH1,SLC36A4,M6PR,TMEM63A,MARCH8,GNS,ZNRF2,VASN,GPC3,GALNS,COL6A1,PCYOX1,DRAM1,PLEKHF1,SLC44A2,TMEM8A,CTSD,ITM2C,TPCN1,P2RX4,MMD,IFITM3,GUSB,LITAF,GNA11,C18orf8,GPLD1,CTSL,FUCA1,SCARB2,CTNS,CTSV,ARRB1,GLB1,CTSA,PLD1,ATP6V1C1,ARSB |
| 1.173e-05 | -11.35 | side of membrane | cellular component | GO:0098552 | 419 | 94 | 17570 | 2579 |
LAMP1,BCAM,TNK1,SLC2A4,IQGAP1,P2RX7,CD274,SNX9,CACNB4,SDC1,FLT3,SPTB,TMC1,BCAP31,TGFBR3,SCNN1A,CDH1,P4HB,IL6ST,CABP1,DLG1,TNFRSF18,DAB2IP,ECE1,TIAM1,GM2A,CLCN3,CR2,EZR,CD40,ALCAM,TAPBP,RTN4RL1,FYN,JAK1,CHMP4B,NRG1,EFNA5,TRAF5,ABCA1,FARP1,LGALS3,SERPINE2,HLA-E,CTSB,RASA2,HLA-F,TRAF2,ITGA6,GNAL,SELL,RACGAP1,TEC,PLPPR4,ANO1,ITGA2B,HLA-A,ICAM1,CALR,ITGA3,CDK16,PTEN,SNX18,CD22,CD9,HLA-C,C10orf54,NCAM1,SYK,S100A6,SPA17,YES1,GNA11,RASA1,CD83,TXK,FAS,GNAS,HLA-B,CD8A,NUCB1,RGS9,LDLRAP1,CTSV,ARRB1,PKD2,CTSA,ITGAV,GEM,JAK3,L1CAM,ESYT2,ABCG1,CD33 |
| 1.177e-05 | -11.35 | SWEET_LUNG_CANCER_KRAS_UP | MSigDB lists | SWEET_LUNG_CANCER_KRAS_UP | 472 | 103 | 17758 | 2588 |
SLC2A4,AVPI1,ST13,AASS,IQGAP1,COL18A1,IL18,PSME1,ITPR2,SDC1,CA8,PHLDA1,TNFSF9,CCND1,EPCAM,CYHR1,SIVA1,ELF5,TACSTD2,MANF,ACSL4,SNX10,CKS2,NEK4,SOAT1,RFK,LAP3,SAT1,ATP1B1,SLC25A5,LCP1,SOCS3,ATP1A1,PAFAH1B3,AREG,KCNK1,AXL,MAP3K11,KLF5,ARF6,RAP1GAP,TM2D2,SERPINE2,LGALS3,CHCHD7,CD63,CTSB,ESRP1,DAP,GNE,AES,CTSZ,NUCB2,PARM1,SIRPA,B4GALNT1,GNS,SPP1,VASP,CTSC,PFKL,TMEM62,RRBP1,CD9,PCYOX1,BRD7,OSTF1,MDFIC,CITED2,CTSD,SLC12A2,ITM2C,EEF1D,KDELR1,WBP5,MDFI,TGIF1,SHMT1,CASK,CRB3,LITAF,PIP4K2C,NPC2,PDK3,NPDC1,ZDHHC3,PRDX4,GALNT3,PTPRF,FUCA1,BTG1,TMEM50B,FNTA,SLC4A4,TMEM30A,FAM3C,CLIP4,FAM117A,CTSA,ATP6V1C1,TOB1,CSRP2,EHD1 |
| 1.185e-05 | -11.34 | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | MSigDB lists | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | 144 | 41 | 17758 | 2588 |
CASP3,TTC39B,GNPDA1,TBC1D1,TSC22D3,ETNK1,FAM102B,RASGRP3,BCL2L1,FAM101B,DHRS3,DUSP5,IL17RB,CDH1,DACT1,KLF3,BCL6,RAB27B,GFI1,TIAM1,SLC12A2,SYTL3,PGM1,PHF20L1,PCGF5,SLC39A8,STAT4,FURIN,DUSP4,SNTB1,STK17B,CD83,NCOA3,BTG1,CSF1,SPINT2,CDCA7L,NR4A3,NFKBIZ,SERPINB6,RRAGD |
| 1.193e-05 | -11.34 | cell surface | cellular component | GO:0009986 | 719 | 147 | 17570 | 2579 |
LAMP1,BCAM,SSH1,AGRN,EPHA4,PDGFB,SDC1,ERP29,TMC1,SPTB,EPCAM,TGFBR3,P4HB,IL6ST,SLC46A1,TNFRSF18,CD55,CR2,ERP44,TNS1,PTGFRN,ENPP1,PLEKHG6,GPRC5B,AREG,MYLK,NOD2,TMEM8B,ARF6,GRN,SCN5A,SERPINE2,LGALS3,ITGA6,HLA-E,HLA-F,RACGAP1,SLC1A3,CNTNAP2,NOTCH2,ANO1,BMP2,CALR,ITGA3,CD22,VASN,TNFRSF12A,NPTN,C10orf54,HLA-C,NCAM1,WNT3A,ULBP2,TSPAN33,IGSF3,MFI2,MICB,ANO6,SPA17,ANTXR1,RHOB,EGFR,FAS,IL1R1,PVRL2,ITGA7,APMAP,NDE1,PROM2,SLC2A4,NF2,IL15,P2RX7,CD274,EMP2,FLT3,CD46,PDGFA,SCNN1A,SRPX,PLK4,ECE1,F2R,HSPA2,SULF2,CLCN3,TIMP2,FZD4,SEPT6,CLSTN1,SLC11A2,CD40,ALCAM,IDE,PTPRJ,RTN4RL1,AXL,NRG1,EFNA5,ANXA9,ABCA1,SORT1,MPZL1,TSPAN15,CD63,CTSB,BACE1,SDC4,LRP4,SELL,PDIA3,PKN1,PLPPR4,SRPX2,ITGA2B,FZD6,HLA-A,ICAM1,PDIA4,CD109,IL17RB,ITGB8,ALPP,CD9,ADAM15,HMMR,PDGFC,RHOA,ADAM17,RC3H2,GRIN1,FURIN,VAMP3,CD83,HLA-B,CD8A,PROM1,ACVRL1,FGFR2,CTSV,ABCB1,ITGAV,FZD5,ARSB,L1CAM,CD33,ABCG1 |
| 1.196e-05 | -11.33 | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | 125 | 37 | 17758 | 2588 |
TCF25,LGALS3,ICAM1,B4GALNT1,ST5,BAX,ACTA2,CLDN4,TACSTD2,TAGLN2,ERBB3,NFKB2,S100A13,TGIF1,ZWINT,TIMP2,PLSCR1,PRSS23,TNIP1,NFE2L1,SLC11A2,RNF19B,BCL10,MAPKAPK2,BTG1,TIMP3,CSF1,PLK2,NFKBIA,WWTR1,KLF5,NFKBIZ,RELL1,GAB1,OCLN,CSRP2,IRF1 |
| 1.196e-05 | -11.33 | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | 125 | 37 | 17758 | 2588 |
CCNE2,CASP3,TP53,ERBB2,EGR3,MGST2,CCNB1,GSTP1,BMP2,WEE1,BTG3,CDH1,TIMP1,PTEN,SHC3,IL6ST,MAP3K9,BAX,DAPK1,CDKN1B,TNFRSF12A,IGFBP2,ERBB3,TIMP2,PLAUR,LITAF,AK4,CDK1,RHOB,FAS,IL1R1,TIMP3,CASP7,NFKBIA,RNASEL,CCNB2,HSPB1 |
| 1.224e-05 | -11.31 | cell cycle phase transition | biological process | GO:0044770 | 301 | 73 | 16441 | 2455 |
CCNE2,ACVR1,CEP70,FOXM1,TUBB4B,PSME2,CUL1,PSME1,CCNB1,PRKACA,CDK14,CDKN2C,CCND1,WEE1,CCNA2,PCNA,PSMD1,CNTRL,CEP78,PSMC2,PLK4,DNM2,TUBG1,CDKN1B,CDKN2D,TUBA4A,PLK1,PRKAR2B,PKMYT1,CDC25C,CDK1,OPTN,PRIM1,PLK2,PSMD3,PPP1CB,KLF11,PSMC1,PPP2R2D,USH1C,PPP1R12A,CIT,EPS8,PSMD7,PSMD10,NES,CKAP5,RB1,E2F7,CENPJ,TUBGCP6,NEK2,CKS1B,IQGAP3,GFI1,PSMA5,CAMK2G,PSMB4,WNT10B,MYBL2,BORA,PSMA4,CDCA5,E2F1,ABCB1,AURKA,SSNA1,CEP41,NDE1,CCNB2,UBE2C,MELK,DMPK |
| 1.230e-05 | -11.31 | testis | COSMIC cancer mutations | testis | 761 | 153 | 17775 | 2585 |
TNK1,ACVR1,CAMKK1,EPHA4,RET,CAMK1D,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,NEB,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,PRKAR2B,ROR1,AURKB,IDH1,ADRBK2,STK17B,ABR,ULK2,PLK2,LIMK1,MYLK,MAP3K11,BMP1,MAPK13,RNASEL,PRKAA2,INPPL1,CDK17,DHPS,PRKAA1,ADCK5,ISYNA1,MERTK,PDXDC1,BMP2K,IGF1R,NEK2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,FNIP1,ALPK1,PIM1,MAPK7,KCTD3,PHKG2,ABCC1,ADCK3,TESK1,DCHS1,STRADB,WHSC1,EIF2AK1,PDK3,PDIK1L,RANBP9,EGFR,STK17A,GNAS,MAPKAPK2,INSR,ALPK3,AURKA,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,TCF25,TRIP10,RPS6KA1,TP53,TESK2,ERBB2,RHPN2,GRK6,PRKACA,DDR1,FLT3,CDK14,SP100,PLK4,EPHB4,SCYL3,MAP3K3,RIPK2,AKT1,PRKCQ,PKMYT1,MAP3K6,EPHA10,DUOX1,FYN,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,PRKAR1A,MAPK12,FAM134B,PINK1,TAOK2,DYRK3,TGFBR1,PKN1,TRIB2,DSE,SNTA1,TMEM87B,ADRBK1,IRAK1,CDK16,TUBGCP6,SGK3,SGK1,H2AFY,BUB1,MAPK11,ERBB3,MAP3K7,SYK,CAMK2G,MYO5A,CASK,ASPM,YES1,BSDC1,TXK,FGFR2,ACVRL1,PRCP,NEIL3,RIN3,WDR91,HIPK3,MELK,GOLGB1 |
| 1.234e-05 | -11.30 | Cdk1 (cyclin-dependent kinase 1) | protein interactions | 12534 | 82 | 29 | 16036 | 2547 |
CDK17,PPP1R12A,CDKN1C,IQGAP1,CCNO,EZR,PKMYT1,PKM,CCNB1,CDC25C,CDK1,GNB2,ARF4,VCP,WEE1,TYMP,IDE,CCNA2,CA2,CDK16,CORO1C,POF1B,SERPINB5,CKS1B,CDKN1B,PPP1CA,CCNB2,ESPL1,CKS2 |
| 1.243e-05 | -11.30 | membrane region | cellular component | GO:0098589 | 1097 | 211 | 17570 | 2579 |
CASP3,GRIK2,RET,EPHA4,SYTL4,HDAC6,PJA2,PDGFB,SLC9A3R2,PICK1,NCS1,EPCAM,CTNNB1,CDKL5,CABP1,SLC46A1,DLG1,DNM2,CLDN4,TRPC1,TACSTD2,RP2,CTTN,PACSIN1,MYRIP,CPE,LAMP2,SGCE,CD55,MGAM,EZR,PRKAR2B,ARF4,LCP1,ENPP1,HPSE,GRID2IP,DNM1L,KCNK1,ATP7B,NOD2,PRKCDBP,PIEZO1,SPRY4,UNC5B,ARF6,LZTS1,DDX58,SCN5A,BVES,ITGA6,PRKAA1,CNTNAP2,NCKAP1,SLC1A3,DHRS3,ANO1,VASP,ITGA3,CA2,IGF1R,ZNRF2,KCNN4,OCRL,FLRT3,FCHO1,PRKCI,NPTN,CNGA1,PIKFYVE,CTSD,SLC12A2,RIMS2,GPR161,ABCC1,EPB41L5,RGMB,SPATA13,SCRIB,ANTXR1,STX3,EGFR,FAS,RASGRP2,EPN3,GABRD,INSR,TJP3,SLC4A4,PHLPP2,TMEM30A,SH3BP4,OSMR,OSCP1,STK39,MAL2,PLD1,ATP1B3,SHROOM2,RUSC1,PROM2,DRD1,EHD1,SPRED1,SORBS1,SLC2A4,NF2,TCTN2,ST14,ERBB2,KCTD12,PRKACA,PRR7,EMP2,APC2,REPS1,EPS8L2,CD46,SCNN1A,CDH1,SMO,CNNM4,PDE4D,DLG3,RAB27B,FLOT2,F2R,DMTN,CYS1,SYNE2,UTRN,CLSTN1,SLC11A2,SYP,ATP1B1,ERBB2IP,CBL,TANC1,DAG1,GABARAPL1,PTGS2,DUOX1,ATP1A1,RTN4RL1,PTPRJ,FYN,STK26,SHROOM3,CORO1C,SIPA1L1,SLC27A1,SPTBN5,NRG1,EFNA5,RGS14,ABCA1,PRKAR1A,TTC8,SORT1,PACSIN2,CTSB,TRAF2,EPS8,LRP4,SDC4,FLOT1,EFHD2,GABRG2,PLD2,EFNB1,SRPX2,FZD6,ICAM1,CAPN2,SNTA1,ANK1,ADORA1,ANKS1B,PTEN,MAGEE1,CD9,ATP8B1,IGFBP2,ERBB3,SPRY2,AMOTL2,DLGAP1,CASK,RHOA,ADAM17,PLSCR1,CRB3,PLAUR,RAPGEF2,GRIN1,FURIN,VAMP3,AIF1L,BBS2,BCL10,LDLRAP1,PROM1,ARRB1,PKD2,GRIN2D,ITGAV,GPER1,L1CAM,OCLN,CYBRD1,ARHGEF4 |
| 1.266e-05 | -11.28 | protein serine/threonine kinase inhibitor activity | molecular function | GO:0030291 | 28 | 14 | 16491 | 2452 |
CDKN2C,CASP3,SPRED1,PRKAG2,CDKN1C,H2AFY,CDKN1B,PRKAR2B,HEXIM2,HSPB1,CDKN2D,SPRY2,PKIA,PRKAR1A |
| 1.297e-05 | -11.25 | STREICHER_LSM1_TARGETS_UP | MSigDB lists | STREICHER_LSM1_TARGETS_UP | 43 | 18 | 17758 | 2588 |
ST13,IL15RA,GATA3,IL13RA1,PDGFB,FZD7,ELF3,SOX13,RBL1,FGFR2,GATA2,MYLK,BCL6,INPP4B,CITED2,HSPB1,NR3C2,ARNT |
| 1.302e-05 | -11.25 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 2156 | 380 | 17775 | 2585 |
GAA,ACVR1,LGR4,HSPG2,TSC22D3,RET,TRAPPC8,PSME1,BAIAP3,CAMK1D,PLXNA1,SLC20A1,PAK6,DAPK2,WEE1,ZYX,MUC4,ZFP36,PPP1R16A,FOSB,AOX1,PIK3CA,PPP1CA,MARCH2,PACSIN1,TIPARP,ANKRD9,NEK4,KIFC2,ACVR1C,PBK,SLC35C1,TNS1,AURKB,SAV1,SPNS3,COL12A1,ULK2,PLK2,LIMK1,MYLK,FAM114A1,MAP3K11,BMP1,DHTKD1,MAPK13,RNASEL,WBSCR27,STARD13,CDK17,INPPL1,FRMD4A,PRKAA1,STRN4,KIF23,NOTCH2,APBA1,MERTK,BMP2K,CALR,FLII,FRY,PIK3AP1,ZIC5,NEK2,DAPK1,PRKG1,ADCK2,MAP3K9,ALPK1,FAM84B,CACNA1D,MAPK7,KANK3,KCTD3,PHKG2,GPR161,EPB41L5,ADCK3,PIP4K2C,KCTD20,WHSC1,RHOB,STK17A,MMP15,CACHD1,SCARB2,PLEKHH2,TJP3,SLC4A4,HTT,AURKA,CDK18,DRP2,MAP3K5,PLIN3,PER3,NRBP1,RPS6KA3,ADAMTS16,DMPK,PKD1L2,DOCK9,TCF25,SLC2A4,NLRX1,TMEM217,ST14,GALNT12,RPS6KA1,IQGAP1,ETNK1,PKP2,TESK2,FAM78A,GRK6,PRKACA,FLT3,DDR1,MOCS1,SLC25A35,MUC16,DAB2IP,EPHB4,MYO5B,COL6A2,RIPK2,COG2,PFKFB2,SEPT6,SYNE2,KIF1C,SLC11A2,PRKCQ,PKMYT1,CBL,ITPR3,ZNF469,EPHA10,PEX5,FYN,PPP2R5A,POPDC3,CCNB3,JAK1,ACAD10,CDK19,AXL,KIAA1804,PNPLA6,SLC27A1,MLKL,RGS14,B4GALT3,SLC25A30,COBL,MAPK12,DENND5B,MRPS9,GALK1,ANKRD13D,TAOK2,TRAF2,PKN1,DNAH3,TSPAN17,ICAM1,SIX4,SNTA1,TMEM87B,FUT2,IRAK1,SLC27A6,FAM160A2,PTEN,KNDC1,TUBGCP6,SGK3,ADAM15,SLC44A2,MAPK11,ERBB3,MAP3K7,ITM2C,TPCN1,MSH6,RASGRF1,CASK,B3GNT2,PIK3R1,CXorf57,PLEKHA7,FURIN,YES1,KIF11,TXK,GPLD1,CRTC2,FGFR2,ACVRL1,PGM2L1,ESPL1,MELK,OCLN,TLL2,LTBP1,TNK1,CPT2,CAMKK1,EPHA4,FHDC1,TAF6L,MGAT5B,GALM,BTG3,RPS6KA2,CTNNB1,P4HB,CDKL5,SLC44A1,ANKFN1,KIF22,TLN2,STK35,PLK1,THRB,ATL1,CD55,MARK1,ING1,CELSR2,FOPNL,CR2,ARFRP1,ROR1,ESYT1,IDH1,ADRBK2,STK17B,TRUB1,TRIM9,PI4K2B,TBC1D17,ZNF114,KCNMB4,HPSE,WIPI1,MAP2,P4HA2,MADD,CTNND1,SP6,TC2N,PRKAA2,ZNF395,PEX6,ATP6V1E2,ADCK5,DOCK11,SPP1,RB1,DAZAP1,IGF1R,GATA2,PFKL,FRAS1,ICAM5,PRKCI,BRAT1,PIM1,TMEM8A,MPHOSPH9,CCDC88A,SNX7,HP1BP3,USP31,TESK1,STRADB,EIF2AK1,PDK3,PDIK1L,C3orf58,RANBP9,EGFR,PRX,GNAS,MAPKAPK2,INSR,ITGA7,PHLPP2,CDCA5,NLRC5,ALPK3,LTBP2,SHROOM2,JAK3,TOB1,CTBP1,FAM45A,KCNAB3,NF2,TP53,ERBB2,TDRKH,FAM198B,ZMYND10,LPIN3,PCBP1,CDK14,TACC2,PLK4,CDH3,F2R,HSPA2,SCYL3,FRS3,CTH,MAP3K3,AKT1,TMTC2,MAP3K6,PAFAH1B3,PTK7,STK38,PSMD3,STAT6,ANXA9,PLXND1,ZBTB6,REEP4,BIN1,PINK1,DYRK3,GOLIM4,CDH22,ENO2,TRAPPC10,MACC1,TAB3,SERPINB9,PSMD10,TGFBR1,COL4A5,NOTUM,JAG2,TRIB2,SBF1,AIP,HMGXB4,NRP2,IRF2BPL,CEP97,ADRBK1,CDK16,TFAP2A,ACTA2,SGK1,ABCD1,BUB1,SYK,CAMK2G,FAM134C,IGDCC4,P2RX4,NFE2L3,NR3C1,COL7A1,AKAP3,BCL10,FAT4,SERPINA1,C2orf70,TMC5,NETO2,UACA,HIPK3,L1CAM,SAT2,RAB3IL1,DIS3L |
| 1.312e-05 | -11.24 | APPEL_IMATINIB_RESPONSE | MSigDB lists | APPEL_IMATINIB_RESPONSE | 32 | 15 | 17758 | 2588 |
GNS,LAMP1,LAMP2,FUCA1,PLSCR1,GUSB,CTSB,OSBPL3,HEXB,ASAH1,CTSZ,CTSA,PLD1,CTSD,GM2A |
| 1.312e-05 | -11.24 | FARMER_BREAST_CANCER_CLUSTER_2 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_2 | 32 | 15 | 17758 | 2588 |
CENPA,CCNA2,KIF20A,ASPM,ESRP1,PTTG1,PRC1,NDC80,NEK2,BUB1,NUSAP1,CENPE,CCNB2,KIF11,MELK |
| 1.312e-05 | -11.24 | MODULE_451 | MSigDB lists | MODULE_451 | 32 | 15 | 17758 | 2588 |
TOP2A,PLK1,PCNA,SORT1,CENPA,PTK7,ESRP1,CDC20,MYBL2,NEK2,KPNA2,CCNB1,CDK1,MELK,UPF3A |
| 1.316e-05 | -11.24 | HALLMARK_E2F_TARGETS | MSigDB lists | HALLMARK_E2F_TARGETS | 199 | 52 | 17758 | 2588 |
DLGAP5,SPC25,DEPDC1,CIT,PTTG1,TP53,CDCA3,CDCA8,RACGAP1,KIF2C,BARD1,LBR,PSIP1,TOP2A,CDKN2C,WEE1,PCNA,UBE2T,RANBP1,PLK4,MSH2,TUBG1,CKS1B,CDKN1B,KIF22,USP1,MXD3,RNASEH2A,SMC4,CKS2,HMMR,PLK1,SHMT1,CDC20,MYBL2,AURKB,POLD3,CDK1,GINS4,PRDX4,DCK,AURKA,DONSON,KPNA2,CENPE,HMGA1,CCNB2,CBX5,E2F8,ESPL1,MELK,RAD21 |
| 1.322e-05 | -11.23 | Signalling to RAS | REACTOME pathways | R-HSA-167044 | 239 | 61 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,RALB,SHC3,PSMC2,DUSP10,MAPK11,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,MAPKAPK3,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,MAPKAPK2,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,MAPK13,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D,MAPK12 |
| 1.326e-05 | -11.23 | biological regulation | biological process | GO:0065007 | 11168 | 1757 | 16441 | 2455 |
HECA,IBTK,GRIK2,PNPLA2,HEXB,RET,ISOC2,BAIAP3,SNX9,SPSB1,CARD10,LTBP3,GRM5,ZNF275,NPM2,CDKN2C,NAPG,PHYHIP,MUC4,ATP13A3,DNM2,CLDN4,CRY2,PPP1CA,TMEM37,TIAM1,IL10RB,TIPARP,CPE,ANKRD9,NEK4,DSTN,UXT,CDA,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,LCP1,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,ATP7B,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,HSPB1,STARD13,ZNF720,SCN5A,GGA1,SEC61G,ITGA6,MTL5,RAB23,GPSM2,FAM21C,HPCAL4,MARCH8,TFAP4,FLII,RAC2,ZCCHC17,PAIP2B,MEGF8,RIMS3,FLRT3,FBXO7,RANBP1,MAP3K9,SLAIN2,USP38,USP1,ALPK1,MYDGF,CNGA1,MAPK7,DGKG,MYLIP,NUP85,PHKG2,PPP6R1,PAQR7,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,PSMA4,GNA11,SFXN5,PLIN5,IL1R1,FNTA,SLC4A4,ETS2,DGAT2,CLMN,OSCP1,STK39,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,ADAMTS16,DOCK9,DMPK,NQO1,LFNG,INPP5D,CD82,PTTG1,MAPK4,GRK6,MGST2,MVB12B,ST5,CDH1,SH3BP1,TAX1BP3,DLG3,RASGEF1A,MYT1,ETV4,MX1,SEC61B,RIPK2,APOBEC3D,PFKFB2,SAT1,VPS4B,HTATIP2,SYP,GTF2A2,SNX12,ZNF618,EBF2,GIGYF1,NFIX,CCNB3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,MAPK12,CTHRC1,TCAF1,HSP90B1,MPZL1,CKAP2,TRAF2,ESRP1,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,CTSZ,PLPPR4,ZNF219,HDGFRP2,IFT27,NFAT5,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,PDCD10,ITGB8,IGSF9,KNDC1,GPC3,FAM20B,CST3,TUBGCP6,BAX,IGFBP2,RAG1,MED22,PARP9,PLSCR1,TACC1,PIK3R1,NUB1,UBE2A,PGBD1,RAB3IP,PIM3,CNTNAP1,LDLRAP1,PROM1,RAB11FIP2,SYT7,SLC35B3,DBI,NR4A3,SSNA1,ITGAV,OSR1,CD81,SRSF9,TMEM131,CCNI,ILDR1,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,LMCD1,PHOSPHO1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,SPTB,SLC9A3R2,FANCI,TFAP2E,SUSD2,BTG3,RPS6KA2,NUP210,CTNNB1,RABEP2,NPNT,P4HB,IL6ST,ARL1,PSMC2,MITF,PASK,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,MARK1,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,NKAIN1,EAF2,SESN1,KDM4D,TRIM9,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,KPNA2,TC2N,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,USH1C,LGALS3,HJURP,DNAJB2,FXYD3,RASA2,PDCL,PSMD7,SORBS3,RAB6A,HES2,NCKAP1,FBLN1,ANO1,B4GALNT1,TNS3,TIMP1,RINL,KIF13B,TBCD,SLC30A6,SELK,PIM1,NTN1,WNT3A,DPYSL5,USP31,RGMB,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,NMT2,CDK5R1,FOXD2,RASGRP2,FA2H,PHLPP2,NLRC5,FAM213A,PLD1,SEMA3A,CCNB2,CDAN1,USP43,RAD21,HOXB7,CTDSPL,TMX4,TP53,P2RX7,RHPN2,BAHD1,STIL,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,KMT5C,TACC2,LMO4,PPME1,BCL6,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,C3orf33,DAG1,ATP13A2,PTGS2,ZNF628,PTPRJ,IDE,ABHD12,RBL1,MMP17,STK38,MAOA,CHMP4B,XRCC3,EFNA5,IRF7,SYT13,ARHGAP4,FAM134B,ARFGEF3,CTDSP1,BIN1,ZMAT1,PINK1,DYRK3,CPEB4,TAB3,CTSB,GNAL,MCTP2,CDCA8,ERCC6L,GTF3A,GDF15,HMGN3,AIP,IL22RA1,PARM1,DNAJB9,FZD6,SH2D4A,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,GTF2F2,UBE2J1,TFAP2A,SGK1,IL17RA,TRIM21,CPLX1,TSPAN13,SYK,FAM134C,ATP2B1,WBP5,DUSP1,NFE2L3,P2RX4,HES1,FBLN5,RHOA,HMGN5,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,COL7A1,TXNDC11,RNPEP,BBS2,DGKE,USP6,BCL10,CNOT2,DDAH1,SCG2,FGF18,E2F1,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,LAMP1,TXN,SSH1,HSPG2,LGR4,TSC22D3,CUL1,PSME1,PDGFRL,CAMK1D,SEPT4,VASH1,PJA2,PICK1,SLC9A7,PAK6,HELZ2,CYP1A1,ZNF823,STIM1,FOSB,KCNS3,SERINC2,PIK3CA,IRF2,TACSTD2,ZBTB18,METAP2,ACVR1C,CDYL,BNIP3L,SLC35C1,LDB2,POR,RAB2B,PRIM1,ANKRD10,SH2D3C,PPP2R4,PRDM5,BMP1,MAPK13,SERPINI1,NFKBIZ,SPRY4,F2RL1,SLC31A2,FGD1,SEMA6B,CDKN1C,SCOC,DHPS,TBC1D1,THEMIS2,PRKAA1,AKAP17A,TXNDC9,APBA1,TNFRSF19,TSPAN7,PSIP1,SH3RF2,MESDC2,C9orf69,CALR,RALGPS2,BHLHE41,VASN,PPP4R1,MSH2,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,DLX4,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,GCC2,PRODH,KCNJ12,KLK5,CALM1,DCHS1,WHSC1,PYGL,NPC2,EPHA1,ATP8B3,ANTXR1,NFIB,PDE11A,MMP15,SLCO4A1,AP1AR,PLEKHH2,TJP3,PELI2,PIAS2,MPP2,FAM83D,APPL2,ARAP1,SFMBT1,CABIN1,KLK7,CDK18,SAMD8,ZBTB34,PER3,IFIH1,EHD1,FOXO6,SPRED1,KIF3C,TCF25,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,NDRG1,ATP2C2,FTH1,BCL2L1,FLT3,DDR1,ZFYVE9,EPS8L2,EPM2A,APOBEC3B,CD46,NOV,CCNA2,ACAP2,RALB,PDE4D,EPHB4,OSBPL7,TSPAN1,FLOT2,MED30,SEMA3B,DOCK4,FOXJ2,DRAP1,UTRN,CLSTN1,ATP1B1,RAD17,PYGO1,PKMYT1,ASB13,CBL,ITPR3,ALCAM,ATP10D,FZD7,POPDC3,ACAD10,NGFRAP1,TSPAN18,TRIOBP,AREL1,CBX7,COBL,PRKAR1A,PLSCR4,DEPDC1,IGFBP6,CENPI,EPS8,NES,CBLL1,PBX3,HERC5,PLD2,SPDL1,FGF19,EFNB1,HLA-A,ADGRB2,WWP2,SCML1,SLC25A36,CKAP5,RASSF8,E2F7,RNF128,GNB5,FUT8,DRAM1,CD9,ERBB3,CITED2,TTPA,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,TCFL5,ZKSCAN2,DIAPH2,FBXO9,YES1,GRTP1,FOS,KIF11,CRTC2,CDK5RAP1,TIMP3,ACADSB,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,FZD5,ESPL1,MELK,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,COMMD5,MAP1LC3B,ERP29,SLC8B1,TRIM68,HTR1D,EPCAM,ZFYVE16,SIPA1L2,RAB15,HSF2,ARHGEF37,CDKL5,SIVA1,TRPC1,ASH2L,CTTN,MYRIP,IL1RAP,SP5,CYP1B1,NLRP4,CXXC5,CENPA,ASXL1,ITCH,USP18,ARHGDIB,TYSND1,GPRC5B,HPSE,KCNK1,MADD,TDRD7,CAB39,ZNF165,SP6,GLA,CHPT1,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,PPP1R12A,BVES,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,DUSP5,QSOX2,SPP1,NOXA1,FAM20C,PFKL,OCRL,SUCO,PRKCI,BRAT1,NPTN,HLA-C,C10orf54,ZRANB1,GAD1,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,PDE5A,KIAA1109,NUBP1,C3orf58,STEAP1,RANBP9,RHPN1,SOX13,INSR,TMEM30A,SH3BP4,RAB31,DCUN1D1,NXPH4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,AFAP1,DRD1,LMO7,CCNE2,LZTFL1,SORBS1,PAX6,HDAC11,SOD2,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,EXT2,MXD1,SAP130,ZNF687,ARTN,CYP4F11,KIF14,REEP1,FABP6,ZBTB49,DIXDC1,ECE1,EPB41L4B,NFKB2,UPF3A,EBAG9,CHP1,CKS2,SOAT1,RFK,PTPRU,GLO1,TMTC2,CD40,CDC25C,CASP4,PDHX,ARHGAP35,SOCS3,HSF4,JADE1,ALDH5A1,STAT6,SECTM1,TLE1,PTBP3,SPTBN5,RCAN2,MAD2L1BP,ABCA1,GLIS3,FBLIM1,GCLM,TSPAN15,ARHGEF11,CIT,SH3D19,ARHGEF7,SERPINB9,TGFBR1,TRIB2,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,ZDHHC13,ACTA2,H2AFY,KANK2,RPGR,MYO5A,DCAF6,WNT10B,SYBU,RC3H2,RGCC,TTC7A,RUNX3,NDRG3,TCEAL8,FOXL1,LEPR,LEMD2,ARHGAP24,CTSL,CD8A,CASP7,SWAP70,RND3,CTSV,SPINT2,RAP2C,DTX4,UACA,ARRB1,MCUR1,ZMIZ1,PLOD3,AHR,RAB3IL1,CD33,ABCG1,NGEF,DOC2A,ACACB,TRIM24,ADD1,IL15RA,TRIM5,DNAJC3,SMARCAL1,FBXO2,XIAP,CACNA2D2,NRG2,LGI3,IL18,MORF4L2,SYTL4,CA8,KIF26A,BARD1,PHF1,TP73,CALM2,DAPK2,WEE1,ZYX,PQLC2,ARHGAP42,PSMD1,TGFBR3,RGS12,AP1M2,CABP1,PPP1R16A,ALDH1A3,SLC46A1,KLF3,RDH14,SEMA3G,ACOX2,PIK3CD,APOBEC3G,ERAP2,TUBA4A,VPS11,SMARCA2,TNIP1,SH3BGRL,SPRTN,LOXL2,F12,ICMT,PPP1R14C,MYOM1,PGF,CAMK2N2,GRID2IP,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,ARF6,LSM14B,E2F8,PDPR,GAB1,HOXC13,NFKBIE,TMTC3,NUAK1,CYP2J2,SOX9,ZNRF3,MERTK,LMNA,ELF3,WDFY1,FAM13B,NEK2,NCAM1,SLC37A1,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,ILK,MEST,TP53INP2,RHOB,DCP2,STK17A,PTPRF,NCOA3,SEMA4D,HTT,SETD3,ITPR1,OSMR,AURKA,MDH1,NDE1,ARPC2,TRPC3,ZNF502,SERPINB1,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,ACTR8,RGS20,WDTC1,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,RNF169,SCN3A,ENPP4,CAMSAP3,SSH3,PSRC1,LGALS8,NRBF2,FZD4,SYNE2,CDCA2,NUSAP1,PXYLP1,RAB38,IRS2,PEX5,STX10,SLC9A6,WWTR1,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,RGS14,GEN1,ARNT,FARP1,TNRC6C,NKX3-1,TAOK2,RBM24,PARP14,RASSF7,PDIA3,GMCL1,ANO9,PKN1,KCNC4,ETS1,GSTP1,ARHGEF40,TSPAN17,SRPX2,HOXB2,TIPRL,ICAM1,NEO1,PDIA4,CAPN2,CXCL16,ANK1,IRAK1,CTSC,KCNK5,MCF2L,FDXR,PLEKHF1,ADAM15,TMBIM6,WWP1,ZNF230,MAPK11,AK3,ITM2C,TPCN1,S100A6,TMX1,CRTAP,HCN3,POU6F1,AMOTL2,LCA5,FMN1,CTNNAL1,BCL9,RAPGEF2,EIF5A2,GRIN1,EMP3,NEURL1B,FAM109A,SKA1,ABLIM2,TXK,PITX2,BTG1,KIAA0141,ATXN7L3,ACVRL1,NR1D2,ZFP30,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,CYBRD1,FOXA1,MYL9,SIGIRR,UNC93B1,TRIM2,AGRN,CUL4B,EPHA4,SUDS3,NDC80,TP53I11,HDAC6,PDGFB,SDC1,PCNA,SHC3,DDHD2,ELF5,DUSP10,TNFRSF18,RGS5,TLN2,ANO4,MYBL1,NEB,S100A13,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,C12orf65,EZR,TNFAIP8L1,ERP44,KLK6,PRKRA,ANLN,IDH1,CLCN2,ZBTB7B,CDK1,VCP,RHEB,PLEKHB1,OPTN,IRX3,DPYSL3,PLCH1,TBC1D17,WIPI1,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,POMT1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,RACGAP1,DOCK11,DHRS3,IL18R1,SSX2IP,CORO1B,BMP2,RB1,VASP,DAZAP1,IGF1R,GATA2,PAK2,MDFIC,PLCB2,PSMA5,CYP26B1,CORO2A,SPATA13,EIF2AK1,TCF7,IFIT3,G2E3,MAPKAPK2,PVRL2,ITGA7,CSF1,LTBP2,ATP1B3,CTBP1,IFI6,RNF146,KCNAB3,AVPI1,NF2,UPF3B,FOXM1,P3H2,DGKA,ZNF28,CCDC68,ERBB2,RASGRP3,CCNL1,SLC7A2,LPIN3,CYP26A1,PER2,CDK14,RAD23A,ATP6V0B,SRPX,LHX6,PLCG2,SCN2A,EGLN3,GM2A,DVL2,CTH,SIRT1,TIMP2,TCEB2,FIGNL1,S100A4,CDC20,MYL12A,MYPOP,DNAJC10,DUOX1,ATP1A1,PSMD3,PTK7,ZBTB6,AIFM3,CNEP1R1,ZNF701,ZC3HC1,PACSIN2,MACC1,CD63,ADGRG1,DAP,GABRG2,PSMD10,SELL,NKRF,JAG2,CRABP2,SIRPA,SLC9A2,PPP2R3A,GBX2,SLC35B4,BUB1,KLF9,HEXIM2,FAIM,CAMK2G,TLE6,PSMB4,IFITM3,NR3C1,AMFR,LITAF,PPARA,CAPNS1,CARD19,TRIM35,FXR2,PELI3,AKAP3,BCAR1,BORA,MAPK8IP1,PRDX4,CD83,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,NMI,NETO2,PPP2R3C,PKD2,SPCS3,ACADM,NDFIP1,TBC1D4,UBE2C,SUN1,GAA,ACVR1,PPP4R4,FAM129B,ATP8A1,KLC2,TAP1,GATA3,PLXNA1,CCNB1,PLA2G16,SLC20A1,FAM101B,ELMOD2,RIC1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IL31RA,STEAP2,ATRNL1,TFG,RCAN3,PACSIN1,XKR8,LAMP2,PBK,CASP9,NBPF3,AGO4,PIF1,AURKB,CCNF,SAV1,SLC25A5,ZFAND5,ARHGEF26,ULK2,SGPP1,AHRR,SFXN1,HLF,SLC25A4,AREG,PLK2,TBX1,NKD1,FAM110C,SARAF,EIF4EBP2,TMEM8B,UNC5B,TRAF5,LZTS1,DLAT,DDX58,KLF2,CDK17,INPPL1,HLA-E,DGKQ,CALB2,SLC25A27,KIF23,SLC1A3,NOTCH2,KIAA1161,BMP2K,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,NECAB3,OPN3,SORL1,CD70,TNFRSF12A,PIKFYVE,TSPAN33,RIMS2,EEF1D,TMED2,EPB41L5,QSOX1,ZNF84,MMD,MFI2,TBC1D8B,B9D2,MICB,AMER1,ANO6,PIP4K2C,KCTD20,CYFIP2,KDM3A,FBXO10,RASA1,STX3,FAS,DGKH,GABRD,SERTAD2,PRKAG2,CSNK1G1,NAB2,SLC4A3,TCEAL4,FGD6,NR4A2,EFNA1,MAP3K5,IRF1,PLA2G4A,PLEKHG3,ELK4,SLC2A4,ARMCX3,NLRX1,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,IRX4,CD274,EGR3,AIFM2,MNS1,GNB2,APLP2,ZNF75D,FAM46A,FICD,DOK4,CNNM4,CDKN1B,TNPO2,DAB2IP,IFIT1,LGMN,NR2C1,TMBIM1,TBC1D10B,MYO5B,CDKN2AIP,CAPN6,DMTN,TEP1,COX11,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,EPHA10,ZNF641,FYN,JAK1,PPP2R5A,STK26,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,NR3C2,ATMIN,DENND5B,OTUD5,WASF3,ARHGEF3,PCOLCE,ATP9A,ARL4C,GPR180,APOBEC3H,SPR,LGALS3BP,TEAD3,SIX4,RND1,SNTA1,FAM111A,OXCT1,PPP1R10,PTEN,CENPJ,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,CNOT6L,MAP3K7,GFI1,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,CASK,DENND1B,MPP1,TEF,VAMP3,FURIN,C1GALT1C1,GPLD1,NUCB1,RGS9,PRDX3,RCBTB2,SERPINB5,GRIN2D,GPER1,ARSB,SLC25A38,CPEB2,USP16,JARID2,EXPH5,EMX1,LTBP1,CASP3,ST13,CAMKK1,KIF2C,TAF6L,CACNB4,DNER,DENND2D,KREMEN1,PTCHD4,SH3KBP1,ARHGEF10L,NKAIN3,GRHL1,ZCCHC12,TSPAN6,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,KIF22,SUN3,RAB20,RP2,MYH14,ARNT2,SLC39A10,PTPRE,RASGRP1,SOD1,TRIM8,ASCL5,SYNE3,STRIP2,RNF165,ROR1,STK17B,ADRBK2,EDNRA,SEC14L2,MDK,CXXC4,NEIL1,ZNF114,ARHGEF19,IARS2,ADIPOR1,APBA2,RAP1GAP,PSMC1,MIIP,PPP2R5D,GRN,PIFO,LRRFIP2,PEX6,ATP6V1E2,PHLPP1,ZNF432,CA2,LRRN2,KCNN4,DIAPH2-AS1,EBF4,FNIP1,FXYD5,ZNF692,KNTC1,RFX5,ACAD8,LRIF1,ALS2CL,HP1BP3,KDELR1,OXR1,GYLTL1B,HMG20B,FBXO8,EGFR,GNAS,FECH,BCAR3,NUDT16,TSC1,ONECUT1,PLPP3,CGREF1,NFKBIA,CDCA5,RHOBTB2,EGFL7,YOD1,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,SLC2A8,PSME2,TDRKH,MICALL2,PATL2,ARHGEF16,SS18,SVBP,SETDB2,FRYL,SMO,GOT1,TWIST1,STEAP3,APIP,F2R,PDIA6,HSPA2,FRS3,MAP3K3,ZNF525,TAF5,BAG4,KREMEN2,ERBB2IP,DUSP4,SNAPC2,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CANT1,PLXND1,AKNA,SGOL1,LIFR,PPP2R2D,CBX4,ANXA3,SORT1,FRMD6,POC1B,LRP4,MIER3,AES,NOTUM,ZNF212,IRF2BPL,IL17RB,SNX13,ADORA1,KIAA0319,CKS1B,BRD7,MXD3,IQGAP3,SUN2,ADAM17,RAB3B,CENPC,ASPM,GCLC,NR4A1,DEPDC4,MBNL3,POLD3,MPV17L2,MAP1B,HLA-B,DHRS2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,ATP6V1C1,SOX8,L1CAM,ZNF596,SNPH |
| 1.326e-05 | -11.23 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | 194 | 51 | 17758 | 2588 |
LMO7,TRIM24,PEX6,ATP8A1,CYP2J2,HDAC11,CACNA2D2,NDRG2,TGFBR1,ITPR2,MGST2,ARHGEF10L,CDKN2C,LLGL2,FICD,PHTF1,DAPK1,KLC3,DUSP10,CLDN4,RAB20,ALDH7A1,ERBB3,NOTCH3,RCAN3,RAG1,DLG3,GFI1,SYTL3,ATG4D,REC8,RASGRF1,MBP,PQLC3,NR3C1,MPP1,SYNE2,EZR,TNFAIP8L1,ATP1B1,C3orf58,DGKE,CYB5A,TXK,LRRC42,PGF,BTG1,STAT1,NR4A3,SH3BGRL2,TMEM131 |
| 1.326e-05 | -11.23 | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | 194 | 51 | 17758 | 2588 |
SPRED1,PARP14,TBC1D1,FRMD6,RASA2,SDC4,KCTD12,CD274,CCNL1,SLC7A2,EGR3,VASH1,PDGFB,BMP2,OTUD1,VASP,RPS6KA2,PPP1R10,FAM20C,RGS3,ZFP36,SLC44A1,BCL6,TNFRSF12A,CITED2,SNX10,TIPARP,C9orf72,SOCS5,DUSP1,ADAM17,B3GNT2,TNIP1,MAPKAPK3,COQ10B,PLAUR,STX3,ARF4,OPTN,HLA-B,AREG,CSF1,AKNA,FZD5,TTC39C,SLC31A2,ST3GAL1,IFIH1,KLF7,USP16,IRF1 |
| 1.328e-05 | -11.23 | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN | 174 | 47 | 17758 | 2588 |
IL15RA,IL15,TRIP10,P2RX7,SAMD9,CD274,HERC6,DUSP5,ICAM1,BTG3,ITGB8,DRAM1,SELK,IFIT1,RASGRP1,LAMP3,DUSP1,ARAP2,RIPK2,TNIP1,PLAUR,STAT4,RAPGEF2,LYRM1,PTGER4,PIM3,RAB3IP,IFIT3,SOCS3,GALNT3,PTGS2,BTG1,MFSD2A,NFKBIA,NETO2,NR4A3,NR4A2,NFKBIZ,IRF7,HS3ST3B1,GEM,CMPK2,IFIH1,KLF7,IRF1,FAM134B,EHD1 |
| 1.331e-05 | -11.23 | positive regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0045737 | 28 | 14 | 16441 | 2455 |
CCND1,CCNC,ADAM17,PSRC1,AKT1,RGCC,PSMD10,PKD2,CCNL1,PIM1,PDGFB,STIL,HSPA2,EGFR |
| 1.333e-05 | -11.23 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 189 | 50 | 17758 | 2588 |
CASP3,LZTFL1,EPAS1,CKAP2,ARHGEF7,ETNK1,C5orf30,GATA3,DHRS3,C11orf95,CMTM6,BMP2K,SSX2IP,PDIA4,PDGFA,RAC2,TAF1B,RIMS3,PPP4R1,OPN3,MSH2,DAPK1,SGK1,BTBD3,SPRY2,SCN3A,PCCB,MCTP1,ERMP1,MMD,PLSCR1,USP18,FHL2,LRRC1,MEST,DCP2,ZMPSTE24,PLCH1,KCNMB4,CORO1C,NEIL3,IARS2,PGRMC1,NR4A3,ABCB1,PLXND1,SPCS3,NDFIP1,PKIA,PHC1 |
| 1.333e-05 | -11.23 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP | 189 | 50 | 17758 | 2588 |
DLGAP5,TUBB4B,SLC25A13,PTTG1,ASL,ABCG2,CDCA8,LMCD1,KIF23,RACGAP1,KIF2C,CCNB1,PLA2G16,FANCI,IL17RB,C7orf49,CCNA2,COL6A1,BAX,PLK4,TPST1,SGCB,CASD1,HMMR,TDP1,SHMT1,ZWINT,KIF20A,CDC20,EMP3,GGH,ARHGDIB,NUSAP1,AURKB,NPDC1,KIF11,CDK1,GALNT3,SEMA4D,PLA2G15,AGBL5,STK39,ZBTB6,UBE2C,CCNB2,CBX5,COBL,ESPL1,E2F8,MELK |
| 1.334e-05 | -11.22 | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | 179 | 48 | 17758 | 2588 |
DDX58,CDK17,TTC39B,IL15RA,IL15,SOD2,GMPR,HERC5,PDGFRL,CD274,HERC6,DUSP5,PLS3,BMP2,DTX3L,ITGB8,GRHL1,DRAM1,MAPK11,IFIT1,ETV7,APOBEC3G,CKAP4,PARP9,MX1,PAPD7,USP18,MICB,NUB1,PTGER4,IFIT3,SOCS3,PI4K2B,CACHD1,CASP7,TRIM69,STAT1,NLRC5,NR4A3,IRF7,NFKBIZ,HS3ST3B1,CMPK2,SLC31A2,IFIH1,CSRP2,MELK,IRF1 |
| 1.335e-05 | -11.22 | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 184 | 49 | 17758 | 2588 |
MTM1,ACACB,SORT1,PACSIN2,REPS2,EPAS1,NLRX1,TBC1D1,RPS6KA1,ZCCHC24,DCAF7,IL13RA1,FTH1,SAMD9,SNN,KBTBD11,IL18R1,DAPK2,RALB,DAPK1,TPST1,PIKFYVE,SYK,OSGIN1,MAP3K3,PIGC,ORAI2,CD55,PLSCR1,AKT1,LPGAT1,MGAM,ERP44,C15orf39,FOS,POR,OSBPL2,FUCA1,GALNT3,SLC6A6,MID1IP1,H1F0,RIN3,SH3GLB2,PPP1CB,GLA,ZMIZ1,RTN3,JARID2 |
| 1.345e-05 | -11.22 | regulation of microtubule-based process | biological process | GO:0032886 | 151 | 43 | 16441 | 2455 |
LAMP1,GAS2L1,CKAP2,ERBB2,RACGAP1,CCNB1,HDAC6,APC2,CTNNB1,TACC2,CENPJ,TUBGCP6,TBCD,NEK2,PLK4,CDKN1B,SLAIN2,DIXDC1,WNT3A,PLK1,CAMSAP3,RHOA,PSRC1,TACC1,CCSAP,VPS4B,STMN3,AURKB,CCNF,SKA1,BBS2,KIF11,BORA,NUBP1,CDK5R1,MID1IP1,PLK2,AURKA,CHMP4B,XRCC3,EFNA5,CFAP20,GEN1 |
| 1.361e-05 | -11.20 | endometrium-carcinoma-adenocarcinoma | COSMIC cancer mutations | endometrium-carcinoma-adenocarcinoma | 51 | 20 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,CDKN2C,RB1,CDH1,CTNNB1,PTEN,FGFR2,MSH2,PIK3CA,SMO,JAK3,MSH6 |
| 1.374e-05 | -11.20 | localization of cell | biological process | GO:0051674 | 853 | 172 | 16441 | 2455 |
TNK1,ACVR1,EPHA4,HEXB,RET,GATA3,F11R,PDGFB,SDC1,DNER,SH3KBP1,PAK6,TGFBR3,LRRC6,CTNNB1,CTGF,CDKL5,ELMO2,DNAH6,MITF,PIK3CA,SEMA3G,PIK3CD,CTTN,TIAM1,CYP1B1,MARK1,CELSR2,STRIP2,TNS1,LOXL2,ANLN,ZFAND5,CDK1,ARF4,LCP1,MDK,PLCG1,TBX1,F2RL1,SEMA6B,LGALS3,BVES,ITGA6,NCKAP1,S100A2,MERTK,CORO1B,SPP1,TNS3,ITGA3,CYR61,GATA2,MEGF8,FLRT3,PAK2,PRKG1,PRKCI,BRAT1,TNFRSF12A,ZRANB1,NTN1,NUP85,CCDC88A,DNAI1,EPB41L5,PODXL2,ANO6,SPATA13,STRADB,SCRIB,ILK,EGFR,CDK5R1,PTPRF,SEMA4D,PLPP3,ITGA7,MATN2,FAM83D,NR4A2,EFNA1,ATP1B3,PLD1,NDE1,SHROOM2,JAK3,SEMA3A,DRD1,INPP5D,EGR3,EMP2,APC2,DDR1,ARHGEF16,NOV,ARTN,LHX6,SMO,DAB2IP,DIXDC1,TWIST1,PDE4D,EPHB4,RASGEF1A,TSPAN1,SCYL3,SEMA3B,DOCK4,SYNE2,PRKCQ,ATP1B1,FYN,JAK1,AXL,PTK7,CORO1C,PEX2,STAT1,NRG1,PLXND1,POMGNT2,CTHRC1,TAOK2,CD63,ADGRG1,ARHGEF7,EPS8,SDC4,SELL,TGFBR1,PLD2,PKN1,ETS1,DNAH3,FGF19,EFNB1,SRPX2,ICAM1,SIX4,SIRPA,SGPL1,GBX2,CXCL16,PDCD10,PTEN,FUT8,KIAA0319,BAX,SYK,PARP9,GCNT1,HES1,ADAM17,RHOA,CFAP46,ASPM,RAPGEF2,NR4A1,PIK3R1,YES1,BCAR1,GPLD1,PITX2,ARHGAP24,BTG1,SCG2,ACVRL1,ITGAV,SOX8,ARSB,L1CAM |
| 1.374e-05 | -11.20 | cell motility | biological process | GO:0048870 | 853 | 172 | 16441 | 2455 |
TNK1,ACVR1,RET,EPHA4,HEXB,GATA3,F11R,PDGFB,DNER,SDC1,SH3KBP1,PAK6,TGFBR3,LRRC6,CTNNB1,CTGF,ELMO2,DNAH6,CDKL5,MITF,PIK3CA,PIK3CD,CTTN,SEMA3G,TIAM1,CYP1B1,MARK1,CELSR2,STRIP2,TNS1,LOXL2,ANLN,ZFAND5,CDK1,ARF4,LCP1,MDK,PLCG1,TBX1,F2RL1,SEMA6B,LGALS3,BVES,ITGA6,NCKAP1,MERTK,S100A2,CORO1B,TNS3,SPP1,ITGA3,CYR61,GATA2,MEGF8,FLRT3,PAK2,PRKCI,PRKG1,TNFRSF12A,BRAT1,ZRANB1,NTN1,NUP85,CCDC88A,DNAI1,EPB41L5,PODXL2,ANO6,SPATA13,STRADB,SCRIB,ILK,EGFR,CDK5R1,PTPRF,SEMA4D,PLPP3,ITGA7,MATN2,FAM83D,NR4A2,EFNA1,PLD1,ATP1B3,NDE1,SHROOM2,SEMA3A,JAK3,DRD1,INPP5D,EGR3,DDR1,EMP2,APC2,ARHGEF16,NOV,ARTN,LHX6,SMO,DIXDC1,TWIST1,DAB2IP,EPHB4,PDE4D,TSPAN1,RASGEF1A,SCYL3,SEMA3B,DOCK4,SYNE2,PRKCQ,ATP1B1,FYN,JAK1,PTK7,AXL,CORO1C,PEX2,STAT1,NRG1,PLXND1,POMGNT2,CTHRC1,TAOK2,CD63,ADGRG1,ARHGEF7,SDC4,EPS8,SELL,PLD2,TGFBR1,PKN1,DNAH3,ETS1,SRPX2,FGF19,EFNB1,SIRPA,SIX4,ICAM1,GBX2,SGPL1,CXCL16,PDCD10,PTEN,FUT8,KIAA0319,BAX,SYK,PARP9,GCNT1,HES1,ADAM17,RHOA,CFAP46,NR4A1,RAPGEF2,ASPM,PIK3R1,YES1,BCAR1,GPLD1,PITX2,ARHGAP24,BTG1,SCG2,ACVRL1,ITGAV,SOX8,ARSB,L1CAM |
| 1.376e-05 | -11.19 | RODRIGUES_DCC_TARGETS_DN | MSigDB lists | RODRIGUES_DCC_TARGETS_DN | 121 | 36 | 17758 | 2588 |
TRIM2,RUNX2,SSH1,TSC22D3,BACE1,EPS8,BIK,SEPP1,CMTM6,CARD8,SCNN1A,FDXR,PIK3CA,BCL6,LIMCH1,PIM1,MYLIP,MAST4,ALDH3A2,RASGRP1,ERAP2,TRAK2,GFPT1,TGIF1,SMARCA2,ELK3,MBP,CORO2A,UTRN,LITAF,SNTB1,BTG1,FYN,AHR,CSRP2,KLF7 |
| 1.391e-05 | -11.18 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | 309 | 73 | 17758 | 2588 |
LMO7,SLC35D2,PAPSS2,IL13RA1,BLCAP,OSR2,PHLDA1,LTBP3,MXD1,CHPF,IER3,ZYX,SIPA1L2,NOV,TGFBR3,FAM46A,DOK4,RGS3,XYLT2,RGS5,ECE1,SULF2,ORAI2,SMARCA2,TIMP2,SAT1,MYOM1,KCNMB4,MAP2,ANKRD6,NFKBIZ,TANC2,ABCA1,GRN,IER5L,MAN2B2,KLF2,FRMD4A,NUAK1,PLEKHJ1,FRMD6,ZCCHC24,HLA-E,FAM134A,SEPP1,LGALS3BP,LMNA,GNS,CYR61,CST3,FAM63A,LIMCH1,CTSD,MYLIP,ITM2C,ATP2B1,IGDCC4,AMOTL2,CYP26B1,HES1,QSOX1,PRSS23,COL7A1,NPC2,TP53INP2,RHOB,GNAS,DDAH1,BTG1,HOXB13,EFNA1,GEM,KLF7 |
| 1.405e-05 | -11.17 | PID_FGF_PATHWAY | MSigDB lists | PID_FGF_PATHWAY | 55 | 21 | 17758 | 2588 |
RUNX2,SSH1,AKT1,PLAUR,RPS6KA1,PIK3R1,CBL,FOS,FGF19,PLCG1,SPP1,CDH1,FGFR2,FGF18,STAT1,PIK3CA,CTNND1,CTTN,NCAM1,SPRY2,GAB1 |
| 1.406e-05 | -11.17 | MODULE_325 | MSigDB lists | MODULE_325 | 51 | 20 | 17758 | 2588 |
LAMP1,FADS2,CXXC5,DLGAP5,UBE2Z,COX11,TFAP2C,POLD3,TP53INP2,CYB5A,APPBP2,PRIM1,NCOA3,NAAA,CYP1A1,HLF,SEMA4D,CDCA5,BDH1,AURKA |
| 1.406e-05 | -11.17 | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | MSigDB lists | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | 51 | 20 | 17758 | 2588 |
GRN,LAMP1,MLEC,PAPSS2,CTSB,SLC39A8,SAT1,SOD2,F11R,SLC17A5,IFIT3,IDH1,FUCA1,SGK1,RPN2,LGMN,TRAM1,GM2A,ATP2B1,TRAK2 |
| 1.408e-05 | -11.17 | negative regulation of mitotic cell cycle | biological process | GO:0045930 | 225 | 58 | 16441 | 2455 |
HECA,NKX3-1,PSME2,CTDSPL,PTTG1,PSMD7,TP53,PSMD10,PSME1,BCL2L1,FANCI,IER3,TP73,CCND1,TOP2A,E2F7,RB1,BTG3,CCNA2,PSMD1,CTNNB1,PTEN,DACT1,BMP7,PSMC2,FBXO7,MSH2,DLG1,CDKN1B,BRD7,BUB1,KANK2,KNTC1,CTDSP2,PSMA5,PLK1,TIMP2,ZWINT,PSMB4,CDC20,RGCC,SCRIB,TRIM35,RAD17,PSMA4,CDK1,JADE1,FGFR2,PLK2,PSMD3,OVOL1,PKD2,FHL1,MAD2L1BP,UBE2C,PSMC1,MIIP,CTDSP1 |
| 1.412e-05 | -11.17 | AKT1 (v-akt murine thymoma viral oncogene homolog 1) | protein interactions | 207 | 285 | 73 | 16036 | 2547 |
CASP3,NF2,IBTK,CAMKK1,IQGAP1,XIAP,BCL2L1,PLXNA1,KTN1,MXD1,PAK6,APLP2,CTNNB1,PIK3CA,CDKN1B,DAB2IP,PPP1CA,SIRT1,AKT1,ASXL1,PFKFB2,SERTAD4,RNF11,CASP9,PLEKHO1,ACO1,IGSF8,PRKCQ,ITPR3,VCP,JADE1,PI4K2B,PLCG1,CARHSP1,ATP1A1,PPP2R4,STAT1,FAM110C,MAP3K11,PPP1CB,HSPB1,PINK1,ENO2,CDKN1C,ARHGEF7,SORBS3,PHLPP1,IRAK1,PTEN,GATA2,ERBB3,CCDC88A,PSMB4,NR4A1,CALM1,PIK3R1,RGCC,ILK,MAPK8IP1,EGFR,BCL10,MAPKAPK2,TSC1,HTT,ITPR1,PIAS2,ARRB1,MDH1,FHL1,MAP3K5,TBC1D4,CD81,CTBP1 |
| 1.414e-05 | -11.17 | Proteoglycans in cancer | KEGG pathways | ko05205 | 203 | 55 | 6908 | 1076 |
CASP3,PPP1R12A,HSPG2,CD63,IQGAP1,SDC4,TP53,ERBB2,MRAS,ITPR2,SDC1,PRKACA,FZD6,CCND1,TFAP4,ANK1,IGF1R,CTNNB1,GPC3,PLCG2,SMO,PIK3CA,TWIST1,MAPK11,PIK3CD,CTTN,ERBB3,PPP1CA,WNT3A,TIAM1,CAMK2G,RHOA,AKT1,WNT10B,FZD4,PLAUR,PIK3R1,EZR,ELK1,ITPR3,CBL,EGFR,FZD7,FAS,CTSL,PLCG1,TIMP3,HPSE,ITPR1,PPP1CB,MAPK13,ITGAV,FZD5,GAB1,MAPK12 |
| 1.414e-05 | -11.17 | Proteoglycans in cancer | KEGG pathways | hsa05205 | 203 | 55 | 6908 | 1076 |
CASP3,PPP1R12A,HSPG2,CD63,IQGAP1,SDC4,TP53,ERBB2,MRAS,ITPR2,SDC1,PRKACA,FZD6,CCND1,TFAP4,ANK1,IGF1R,CTNNB1,GPC3,PLCG2,SMO,PIK3CA,TWIST1,MAPK11,PIK3CD,CTTN,ERBB3,PPP1CA,WNT3A,TIAM1,CAMK2G,RHOA,AKT1,WNT10B,FZD4,PLAUR,PIK3R1,EZR,ELK1,ITPR3,CBL,EGFR,FZD7,FAS,CTSL,PLCG1,TIMP3,HPSE,ITPR1,PPP1CB,MAPK13,ITGAV,FZD5,GAB1,MAPK12 |
| 1.422e-05 | -11.16 | - | gene3d domains | 1.20.900.10 | 71 | 26 | 9988 | 1574 |
PLEKHG3,RASGRF1,ARHGEF28,ARHGEF3,FARP1,ARHGEF11,ARHGEF7,SPATA13,ARHGEF40,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,MCF2L,PLEKHG1,FGD6,TIAM1,ALS2CL,ARHGEF9,NGEF,ARHGEF4,FGD1,FARP2 |
| 1.434e-05 | -11.15 | Resolution of Sister Chromatid Cohesion | REACTOME pathways | R-HSA-2500257 | 100 | 32 | 8202 | 1235 |
SPC25,CENPI,NDC80,ERCC6L,CDCA8,NUF2,KIF2C,CCNB1,SPDL1,CENPN,CKAP5,BUB1,KNTC1,NUP85,PLK1,CENPA,ZWINT,CENPC,B9D2,CDC20,AURKB,SKA1,CDK1,PPP2R5A,CDCA5,CENPE,NDE1,NUP37,CCNB2,SGOL1,PPP2R5D,RAD21 |
| 1.441e-05 | -11.15 | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | 220 | 56 | 17758 | 2588 |
AGRN,TRIM24,SERPINE2,PPP1R12A,ZCCHC24,CD82,ETV5,CTDSPL,RET,ARL4C,CCNL1,EMP2,MNS1,DUSP5,MECOM,NEO1,HDAC9,SS18,PCNA,NUP210,CYR61,METTL7A,ZFP36,UBE2J1,TMEM51,LIMCH1,HLA-C,FAIM,ALDH3A2,NCOA2,ATP2B1,GFPT1,TGIF1,ADAM17,MBP,ING1,NR3C1,LGALS8,S100A4,HTATIP2,IDH1,FOS,GABARAPL1,STK17A,BTG1,PTGS2,ETS2,KCNK1,SLC9A6,HOXA9,RAP2C,CSGALNACT1,MAP3K11,ERAP1,PITPNA,CBX4 |
| 1.473e-05 | -11.13 | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | 112 | 34 | 17758 | 2588 |
PLA2G4A,TRIM2,LRP4,SOX9,LMCD1,DNER,CDH1,LMO4,ALDH1A3,BCL6,WWP1,IGFBP2,KLF9,TSPAN1,EGLN3,CYP1B1,LAMP2,PDGFC,SLC39A8,CYS1,TFAP2C,CALCRL,TANC1,SESN1,MAP3K6,STK17B,FZD7,ARHGEF26,ATP1A1,PDLIM3,FGFR2,TLE1,LRRK1,MAFF |
| 1.482e-05 | -11.12 | GGGTGGRR_V$PAX4_03 | MSigDB lists | GGGTGGRR_V$PAX4_03 | 1241 | 233 | 17758 | 2588 |
ACVR1,ADD1,HSPG2,UBE2Z,NRG2,PHOSPHO1,NDRG2,PSME1,MORF4L2,HDAC6,PDGFB,KREMEN1,PHF1,SPTB,HTR1D,PLS3,PHYHIP,P4HB,DPYSL2,KLF3,NTN4,SEMA3G,FGFR1OP2,TUBA4A,ZNF462,PCGF5,SMARCA2,TRIM8,CD55,FBXL16,TNIP1,SH3BGRL,SERTAD4,RNF11,NFE2L1,TMEM151A,TNS1,ARHGDIB,PRKAR2B,ZFAND5,SESN1,PNKD,ABR,CAMK2N2,KLF12,SH2D3C,MAP3K11,SH3GLB2,HDAC1,CTNND1,SERPINI1,TMEM8B,GLA,SPRY4,STARD13,RTN3,MAFF,RRAGD,HS6ST3,LASP1,CDK17,BMF,FRMD4A,ITGA6,ETV5,NOTCH2,RAB6A,DOCK11,APBA1,DUSP5,HPCAL4,LRRN2,ZIC5,FAM13B,KNTC1,CACNA1D,PIM1,WNT3A,NTN1,PHKG2,IGSF3,CYP26B1,DPYSL5,ELK3,DCHS1,SPA17,VWA1,EPHA1,PDK3,KDM3A,UNC45B,GOLT1A,RASA1,RASGRP2,BCAR3,PTPRF,MAGED2,NCOA3,COL13A1,MFSD2A,NAB2,C1orf21,AGBL5,MPP2,RHOBTB2,KLK7,ARPC2,RARG,TOB1,RPS6KA3,KLF7,IRF1,DMPK,KIF3C,SLC25A24,SLC2A4,PAX6,CAST,IQGAP1,THRA,RALBP1,CERCAM,ABCG4,TP53,KCTD12,EGR3,GRK6,BAHD1,PRR7,GNB2,BCAP31,KCTD9,RAD23A,SAP130,NOV,CCNA2,SH3BP1,RALB,CDKN1B,TNPO2,TAX1BP3,DAB2IP,DLG3,SEMA3B,AKT1,FZD4,FOXJ2,LYRM1,KIF1C,CDCA2,MAP3K6,SNX12,SP4,GIGYF1,FZD7,NIN,NFIX,FYN,PPP2R5A,RBL1,PTK7,SLC9A6,AXL,STAT6,NRG1,KLF5,C1orf43,RGS14,REEP4,OTUD5,FARP1,IGFBP6,ENO2,CD63,SLC41A1,BLVRB,ARL4C,GABRG2,CBLL1,TGFBR1,TRIB2,TSPAN17,HOXB2,EFNB1,TEAD3,SIX4,IRF2BPL,CD109,KIF5B,ADD3,PDCD10,ANKS1B,BMP7,TUBGCP6,FUT8,CKS1B,ATP8B1,H2AFY,ABCD1,WWP1,TSPAN13,SPRY2,RBMS2,IGDCC4,WBP5,NFE2L3,PVRL4,ACBD5,RHOA,NR3C1,PHLDB3,NR4A1,DEPDC4,RUNX3,MAP1B,PITX2,SMTNL2,HNRNPH2,NR4A3,OTUB2,SERPINB5,GRIN2D,PPP2R3C,SH3BGRL2,HOXB13,FHL1,HMGA1,OSR1,USF2,PTGES,AHR,PKIA,RGMA |
| 1.492e-05 | -11.11 | MODULE_66 | MSigDB lists | MODULE_66 | 531 | 113 | 17758 | 2588 |
TRIM2,PAX6,EPAS1,CRYM,THRA,EPHA4,TMX4,CACNA2D2,C5orf30,NRG2,BAIAP3,PLA2G16,APC2,PHLDA1,PHYHIP,SRPX,TACC2,CABP1,LMO4,ALDH1A3,RGS5,ARNT2,IFIT1,BTBD3,CPE,HSPA2,TMCC2,SGCE,MBP,COL6A2,CBX6,KLK6,ROR1,ATP1B1,LDB2,ALCAM,PLEKHB1,FZD7,DPYSL3,MDK,TRIM9,GPRC5B,MAP2,KCNK1,MYLK,TLE1,MAOA,RCAN2,SERPINI1,ITPKA,APBA2,NRGN,BIN1,WASF3,COL9A3,ENO2,CDH22,IGFBP6,ATP9A,DNAJB2,ITGA6,SOX9,CALB2,GABRG2,CNTNAP2,SLC1A3,SEPP1,TSPAN7,DUSP5,PARM1,RND1,NEO1,ELF3,DIRAS3,SPP1,CA2,GPC3,NECAB3,RIMS3,IGFBP2,ALDH7A1,HSPA13,NCAM1,GAD1,PLCB2,RIMS2,ATP2B1,EPHX1,FADS2,NR4A1,BCL9,GRIN1,FOS,DPYSL4,RHOB,TIMP3,SERPINA1,DGCR2,RND3,FGFR2,SCG2,ITGA7,ITPR1,NAB2,RAB31,TCEAL4,CDK18,STK39,L1CAM,CSRP2,PKIA,ARHGEF4,SNPH |
| 1.498e-05 | -11.11 | XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR | 19 | 11 | 17758 | 2588 |
MX1,PLSCR1,CYR61,PLAUR,IRF7,TRMT2B,ERBB2IP,IFIT1,OAS3,MAFF,IFI6 |
| 1.498e-05 | -11.11 | LE_NEURONAL_DIFFERENTIATION_DN | MSigDB lists | LE_NEURONAL_DIFFERENTIATION_DN | 19 | 11 | 17758 | 2588 |
E2F7,RGS12,CDC20,LHX6,KIF23,EIF4EBP2,PKMYT1,UBE2C,CCNB2,CDC25C,CKS2 |
| 1.498e-05 | -11.11 | VISALA_AGING_LYMPHOCYTE_DN | MSigDB lists | VISALA_AGING_LYMPHOCYTE_DN | 19 | 11 | 17758 | 2588 |
SOAT1,COL9A3,UFD1L,LGALS3,STAT4,SDC4,NRG2,CDK18,RUNX3,PLA2G16,TXK |
| 1.501e-05 | -11.11 | regulation of mitotic cell cycle phase transition | biological process | GO:1901990 | 256 | 64 | 16441 | 2455 |
DLGAP5,PSME2,CUL4B,CTDSPL,TP53,CUL1,PSME1,CCNB1,FANCI,IER3,TP73,NPM2,CCND1,CYP1A1,CCNA2,PSMD1,DACT1,KIF14,PSMC2,CDKN1B,HSPA2,CTDSP2,PLK1,AKT1,CDC20,VPS4B,PRKCQ,ANLN,CDK1,JADE1,CCNB3,PSMD3,MAD2L1BP,PSMC1,MIIP,CTDSP1,PSMD7,PSMD10,RB1,E2F7,PTEN,FBXO7,BRD7,KANK2,BUB1,PIM1,KNTC1,ERCC2,PSMA5,ADAM17,PSMB4,WNT10B,RGCC,PSMA4,EGFR,TJP3,CDCA5,E2F1,PKD2,CENPE,FHL1,UBE2C,ESPL1,PKIA |
| 1.540e-05 | -11.08 | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | MSigDB lists | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | 85 | 28 | 17758 | 2588 |
CCNE2,PPIF,ZWINT,DLGAP5,CDC20,NDC80,RACGAP1,NUSAP1,GGH,KIF2C,KIF11,CDK1,LEPR,SAC3D1,APOBEC3B,TOP2A,PCNA,CCNA2,AMMECR1,PRC1,MSH2,CKS1B,BUB1,RNASEH2A,MINPP1,CCNB2,NUP85,MELK |
| 1.541e-05 | -11.08 | GSE6269_FLU_VS_STREP_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_FLU_VS_STREP_AUREUS_INF_PBMC_DN | 165 | 45 | 17758 | 2588 |
SEMA6B,PINK1,AGRN,IGFBP6,REPS2,EPAS1,PNPLA2,SDC4,SOD2,PLD2,NENF,CMTM6,LMNA,MARCH8,CTNNBIP1,ATP6V0B,CALD1,CABP1,ICAM5,SORL1,STEAP3,ETHE1,CPD,OPLAH,KCNJ12,MPP1,VAMP3,BNIP3L,PCTP,ALCAM,ZDHHC3,SEC14L2,PIAS3,KIAA0141,HOXA9,MATN2,RAB31,ZDHHC7,PITPNA,NRG1,EIF4EBP2,LZTS1,RTN3,CYBRD1,RRAGD |
| 1.545e-05 | -11.08 | FUJII_YBX1_TARGETS_DN | MSigDB lists | FUJII_YBX1_TARGETS_DN | 195 | 51 | 17758 | 2588 |
SPC25,FAM169A,DEPDC1,FOXM1,DNAJC3,KIF23,CENPN,FANCI,TOP2A,CXCL16,E2F7,MDM1,OXCT1,PPP1R10,MGAT4A,BMP7,PLK4,CKS1B,RNASEH2A,MYBL1,TIAM1,MPHOSPH9,IL1RAP,CLCN3,ELK3,ZWINT,FIGNL1,ASPM,MICB,SPA17,MYBL2,WHSC1,NUSAP1,UBAC1,PRKAR2B,CCNF,KIF11,CDC25C,H2AFV,PRIM1,TIMP3,TIMM8A,TWSG1,ZNF367,NEIL3,ITPR1,XRCC3,EIF4EBP2,NCAPG2,PTGES,MELK |
| 1.545e-05 | -11.08 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN | 195 | 51 | 17758 | 2588 |
CCNE2,TXN,HJURP,NQO1,VANGL1,CDCA3,ABCG2,CDCA8,KIF23,RACGAP1,KIF2C,CCNB1,SAC3D1,CKAP5,TOP2A,TYMP,PCNA,KCNK5,TUBG1,CKS1B,LGMN,PXMP4,FAH,LAMP3,GCNT1,CKS2,HMMR,ALDH2,CENPA,SHMT1,HN1L,KIF20A,ASPM,CDC20,NUSAP1,AURKB,RAB38,SLC25A5,KIF11,CDC25C,SKA1,ADRBK2,PRDX4,IL1R1,SLCO4A1,CENPE,NCAPG2,CCNB2,UBE2C,ESPL1,ACOT7 |
| 1.556e-05 | -11.07 | immune system process | biological process | GO:0002376 | 2162 | 389 | 16441 | 2455 |
TXN,ADD1,LGR4,TRIM5,AK7,DNAJC3,KLC2,RET,TAP1,CUL1,NRG2,GATA3,PSME1,IL18,DPP8,KIF26A,ELMOD2,CALM2,PSMD1,AP1M2,TGFBR3,ELMO2,IL31RA,POLL,PIK3CA,DNM2,IRF2,TINAGL1,PIK3CD,IL10RB,TIPARP,APOBEC3G,ERAP2,SPEF2,TNIP1,CASP9,BNIP3L,AGO4,PRKAR2B,F12,RNF19B,LCP1,SFXN1,ENPP1,PLCG1,LIMK1,TBX1,NOD2,DHTKD1,RNASEL,F2RL1,GAB1,DDX58,KLF2,INPPL1,CDKN1C,THEMIS2,SEC61G,ITGA6,HLA-E,AKAP17A,KIF23,NOTCH2,HERC6,MERTK,MECOM,MARCH8,CALR,ITGA3,PIK3AP1,RPL39,CTPS1,MSH2,DAPK1,CD70,NCAM1,CTSD,MAPK7,ULBP2,NUP85,MAPKAPK3,MICB,CALM1,ANO6,ELK1,CYFIP2,PSMA4,RASA1,FAS,IL1R1,SEMA4D,PELI2,ITPR1,RAET1L,ARPC2,MAP3K5,IFIH1,RPS6KA3,TMEM173,IRF1,KIF3C,SPRED1,NLRX1,LFNG,TUBB4B,THRA,INPP5D,RPS6KA1,NDRG1,FTH1,BCL2L1,CD274,PRKACA,FLT3,TNFSF9,APOBEC3B,CD46,SP100,CDKN1B,DAB2IP,RTKN2,PDE4D,IFIT1,RASGEF1A,LGMN,SNX10,MX1,SEC23A,SEC61B,RIPK2,APOBEC3D,LGALS8,DMTN,PRKCQ,SLC11A2,ATP1B1,PYGO1,ITPR3,FZD7,CMTM7,IRS2,FYN,JAK1,DDOST,AXL,STAT1,NRG1,PRKAR1A,OTUD5,TNRC6C,HSP90B1,TRAF2,EPS8,BTN3A1,PDIA3,HERC5,APOBEC3H,PLD2,PKN1,ETS1,FGF19,ICAM1,HLA-A,SIX4,SGPL1,CXCL16,FAM111A,IRAK1,CTSC,PTEN,GPC3,BAX,ADAM15,MAPK11,ERCC2,ERBB3,CITED2,MAP3K7,RAG1,GFI1,CNPY3,TRIM62,MSH6,FARP2,RASGRF1,PLSCR1,RAPGEF2,PIK3R1,NUB1,GRIN1,UBE2A,FBXO9,YES1,FOS,KIF11,TXK,GPLD1,DCTN6,PITX2,FGFR2,PRDX3,NR4A3,ERAP1,GRIN2D,ITGAV,GPER1,CENPE,LRRK1,FZD5,SLC25A38,MELK,JARID2,UNC93B1,TNK1,CASP3,EPAS1,F11R,ITPR2,KIF2C,CACNB4,PDGFB,TRIM68,SPTB,SUSD2,RPS6KA2,CTNNB1,SHC3,SIVA1,PSMC2,MITF,TMEM143,DLG1,TNFRSF18,KIF22,ASH2L,SCARA3,IL1RAP,S100A13,RASGRP1,LAMP3,NLRP4,SOD1,CD55,TRIM8,ITCH,USP18,NFE2L1,CR2,ARHGDIB,PRKRA,ANLN,HOXA9,PSMC1,PPP2R5D,RUNX2,LGALS3,BVES,HLA-F,RASA2,PSMD7,CALM3,RACGAP1,NCKAP1,TEC,RAB6A,PHLPP1,DUSP5,IL18R1,SPP1,RB1,VASP,IGF1R,GATA2,FAM20C,KIF13B,KCNN4,PAK2,FNIP1,AHCY,HLA-C,WNT3A,PSMA5,PODXL2,BTN3A2,TCF7,EIF2AK1,IFIT3,EGFR,FECH,MAPKAPK2,ONECUT1,TSC1,PHLPP2,CSF1,NFKBIA,NLRC5,ATP1B3,CCNB2,JAK3,IFI6,HOXB7,IL15,PSME2,TP53,ERBB2,P2RX7,IL27RA,RASGRP3,SLC7A2,EMP2,BCAP31,PDGFA,ARTN,LMO4,PLCG2,BCL6,OAS3,NFKB2,FRS3,MBP,AKT1,OSTM1,PTGER4,GLO1,DUSP4,CD40,SOCS3,TAPBP,PTPRJ,STAT6,PSMD3,SECTM1,PTBP3,IRF7,SPTBN5,RPL22,ANXA3,DYRK3,TAB3,CTSB,ARHGEF7,SERPINB9,PSMD10,SELL,TGFBR1,JAG2,SIRPA,HDAC9,CD109,TOP2A,ADRBK1,TRIM21,SYK,CAMK2G,GCNT1,HES1,ADAM17,RHOA,RAB3B,PSMB4,WNT10B,IFITM3,NR4A1,RC3H2,CRIP2,RGCC,TTC7A,RUNX3,TRIM35,BCAR1,FOXL1,CD83,BCL10,CTSL,HLA-B,CD8A,BANK1,SWAP70,SCG2,TWSG1,DHRS2,CTSV,FGF18,DTX4,UBE2D2,PPP2R3C,GEM,ICOSLG,L1CAM |
| 1.556e-05 | -11.07 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | MSigDB lists | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | 190 | 50 | 17758 | 2588 |
UNC93B1,INPPL1,TRIM2,AASS,ATP8A1,ERBB2,IL27RA,FTH1,SPTB,PPP2R3A,C1orf116,ICAM1,PARM1,CDS1,PLS3,CAPN2,APLP2,BTG3,RPS6KA2,RIMS3,ICAM5,KCNS3,LIMCH1,CITED2,TIPARP,S100A13,EPHX1,DUSP1,CD55,ELK3,NR3C1,SLC39A8,RAPGEF2,RAB38,BLVRA,ZFAND5,MAP3K6,CYB5A,PIAS3,ALDH3B1,NAAA,ALDH5A1,NFKBIA,NAB2,RHOBTB2,MAOA,ARRB1,GEM,ITPKA,LTA4H |
| 1.556e-05 | -11.07 | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP | 190 | 50 | 17758 | 2588 |
GALK1,DLGAP5,HJURP,TUBB4B,PTTG1,ASL,CDCA8,GATA3,ZMYND10,KIF2C,ITPR2,CCNB1,CENPN,IL18R1,FANCI,RAC2,DAZAP1,CCNA2,FUT8,PRC1,PLK4,CKS1B,KIF22,BUB1,KNTC1,RNASEH2A,CKS2,ZWINT,CENPA,PSRC1,CASP9,CDC20,MYBL2,WHSC1,NUSAP1,AURKB,DUSP4,NPDC1,KIF11,SLCO4A1,CSTF2,AURKA,EIF4EBP2,DONSON,CENPE,NCAPG2,UBE2C,CBX5,CCNB2,MELK |
| 1.556e-05 | -11.07 | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN | 190 | 50 | 17758 | 2588 |
MAN2B2,LMTK3,FAM129B,MCTP2,RASGRP3,NOTCH2,BAHD1,VASH1,CYP26A1,PDGFA,CPNE2,PHYHIP,CA2,FAM46A,VASN,OSBPL3,FUT8,PPP4R1,CAPG,C10orf54,EPB41L4B,SYTL3,MED30,GPR161,FAH,DLGAP1,CPD,ELK3,NR4A1,CORO2A,MPP1,PTGER4,MBNL3,PRICKLE1,DUSP4,TMTC2,ALCAM,TXK,GALNT3,SLC6A6,KCNMB4,C1orf21,FAM83D,NFKBIZ,SERPINB1,ARNT,NRBP1,MYL12B,ANXA11,FAM134B |
| 1.556e-05 | -11.07 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | 190 | 50 | 17758 | 2588 |
SLC25A24,AGRN,TRIM5,ATP8A1,CTSB,PRKAA1,TAP1,TP53,SELL,NKRF,SLC36A4,NOTCH2,PLA2G16,DSE,HERC6,LGALS3BP,SIRPA,ICAM1,IL17RB,NUP210,KHNYN,IRAK1,CTSC,FAM189A1,RIMS3,UBE2J1,RPN2,TMEM8A,ITM2C,ALS2CL,MED22,XKR8,PARP9,NWD1,SPEF2,PTPN18,TIMP2,MAPKAPK3,KIAA0040,NR4A1,LITAF,PTGER4,RUNX3,TMEM50B,SWAP70,MADD,C1orf21,NDFIP1,F2RL1,CBX4 |
| 1.556e-05 | -11.07 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN | 190 | 50 | 17758 | 2588 |
NFKBIE,PPP1R2,EPAS1,DCAF7,MCTP2,SDC4,TAP1,FLOT1,KIF23,NDUFA4,STIL,BMP2K,SPP1,PSMD1,OXCT1,PTEN,CKS1B,AKR1B1,TRIM21,DIXDC1,APIP,RNASEH2A,OAS3,LMAN1,BTBD3,SCN3A,FAH,CKS2,CENPA,PLSCR1,MAPKAPK3,SLC39A8,C3orf52,GGH,NUSAP1,PDK3,PCTP,CDC25C,STEAP1,SLCO4A1,CDCA4,MID1IP1,PRDX3,TWSG1,H1F0,PSMD3,RAB11FIP1,GLA,NCAPG2,SERPINB1 |
| 1.563e-05 | -11.07 | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | MSigDB lists | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | 185 | 49 | 17758 | 2588 |
BIN1,CCNI,SPRED1,SEMA6B,TRIM2,CEP70,ATP8A1,CBLL1,SLC1A3,TNFRSF19,TTYH3,NCS1,IGF1R,SNX18,IMPAD1,FJX1,DNM2,TNPO2,H2AFY,DAB2IP,KLF9,FAR1,ATP2B1,SMARCA2,TRIM8,TIMP2,ACVR1C,ZC3H11A,TEF,SNTB2,LPGAT1,PIK3R1,RNF165,CYFIP2,FNDC3A,ADRBK2,SP4,CDK5R1,NFIX,ENDOD1,PTPRJ,SLC4A4,PGM2L1,PCDH19,TMOD2,RPL22,CPEB2,NR2C2,EGLN1 |
| 1.573e-05 | -11.06 | regulation of cell cycle phase transition | biological process | GO:1901987 | 277 | 68 | 16441 | 2455 |
DLGAP5,PSME2,CUL4B,CTDSPL,TP53,CUL1,PSME1,CCNB1,FANCI,IER3,TP73,NPM2,SUSD2,CCND1,CYP1A1,CCNA2,PSMD1,DACT1,KIF14,PSMC2,CDKN1B,HSPA2,CTDSP2,PLK1,AKT1,CDC20,VPS4B,PRKCQ,ANLN,CDK1,JADE1,CCNB3,PSMD3,OVOL1,MAD2L1BP,PSMC1,MIIP,CTDSP1,PSMD7,PSMD10,RB1,E2F7,PTEN,FBXO7,BRD7,H2AFY,KANK2,BUB1,PIM1,KNTC1,ERCC2,PSMA5,ADAM17,PSMB4,WNT10B,RGCC,PSMA4,EGFR,TJP3,CDCA5,FAM83D,E2F1,PKD2,CENPE,FHL1,UBE2C,ESPL1,PKIA |
| 1.573e-05 | -11.06 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | MSigDB lists | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | 36 | 16 | 17758 | 2588 |
AKT1,RPS6KA1,FLOT1,ITPR2,ITPR3,PITX2,RPS6KA2,PTEN,ITPR1,PLCG2,NR4A3,PIK3CA,FLOT2,SYK,GAB1,RPS6KA3 |
| 1.573e-05 | -11.06 | CELL_MATRIX_ADHESION | MSigDB lists | CELL_MATRIX_ADHESION | 36 | 16 | 17758 | 2588 |
SGCE,TAOK2,SORBS1,FBLN5,NF2,TESK2,RASA1,TSC1,ITGA3,COL13A1,ACVRL1,PTEN,ITGA7,ADAM15,PKD2,TMEM8B |
| 1.577e-05 | -11.06 | EGFR1 Signaling Pathway | WikiPathways | WP437 | 177 | 51 | 4455 | 729 |
ELK4,INPPL1,REPS2,RPS6KA1,RALBP1,EPS8,PLD2,REPS1,SH3KBP1,ELF3,RPS6KA2,RALB,PLCG2,PRKCI,PIK3CA,PIK3CD,MAPK7,SPRY2,DUSP1,MAP3K3,TGIF1,PLSCR1,AKT1,TNIP1,ITCH,SH3BGRL,PIK3R1,CASP9,CBL,ELK1,FOS,BCAR1,ARF4,RASA1,EGFR,SOCS3,PLCG1,JAK1,HTT,SH2D3C,STAT1,APPL2,HDAC1,CTNND1,PIK3C2B,KLF11,PITPNA,PLD1,GAB1,RPS6KA3,PRKAR1A |
| 1.579e-05 | -11.06 | RhoGEF | pfam domains | PF00621 | 70 | 25 | 16629 | 2504 |
PLEKHG3,RASGRF1,ARHGEF28,ARHGEF3,FARP1,ARHGEF11,ARHGEF7,SPATA13,ARHGEF40,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,MCF2L,PLEKHG1,FGD6,TIAM1,ARHGEF9,NGEF,ARHGEF4,FGD1,FARP2 |
| 1.580e-05 | -11.06 | glycoprotein biosynthetic process | biological process | GO:0009101 | 399 | 91 | 16441 | 2455 |
GALNT12,XYLT1,NANS,MGAT5B,PHLDA1,ART5,EXT2,CHPF,MUC16,MUC4,XYLT2,FUT1,RPN2,LMAN1,TFG,TIPARP,MGAT5,SIRT1,SEC23A,TNIP1,PXYLP1,GALNT7,SLC17A5,B3GALNT2,MCFD2,ARF4,VCP,MAN2A2,HS6ST1,DDOST,AREG,DOLPP1,GNPTAB,CANT1,HS3ST3B1,B4GALT3,POMT1,ST3GAL1,NDST3,POMGNT2,HS6ST3,CMAS,TRAPPC10,MAN1A2,GNE,PDIA3,CTSZ,B4GALT4,DSE,POMGNT1,ADAMTSL4,B4GALNT1,CALR,B3GALNT1,FUT2,CTSC,MGAT1,A4GALT,MGAT4A,ALG13,FUT8,UBE2J1,STT3B,SLC35A1,PPP6R1,TMED2,GCNT1,TRAK2,CHSY3,GFPT1,B3GALT6,NAGPA,B3GNT7,MLEC,B3GNT2,MGAT4B,GYLTL1B,PARP4,C1GALT1C1,COL7A1,FOXL1,GLCE,GALNT3,FUCA1,UAP1,SERPINA1,CSGALNACT1,GLB1,CTSA,ALG2,B4GAT1 |
| 1.582e-05 | -11.05 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | 117 | 35 | 17758 | 2588 |
LMO7,HSP90B1,ENO2,CTSB,PHLDA1,PTEN,NPNT,ATP13A3,TPST1,AOX1,TWIST1,NCAM1,SLC12A2,LOXL1,F2R,CYP1B1,LAMP2,CASK,PLSCR1,CAPN6,PDK3,GTF2A2,CASP4,IL1R1,FGFR2,CSF1,FAM3C,UBE2D2,PGRMC1,OSMR,LTBP2,CCNB2,MYL12B,NGEF,XDH |
| 1.582e-05 | -11.05 | MISSIAGLIA_REGULATED_BY_METHYLATION_DN | MSigDB lists | MISSIAGLIA_REGULATED_BY_METHYLATION_DN | 117 | 35 | 17758 | 2588 |
DLGAP5,FOXM1,CYP2J2,KIF23,LBR,PSIP1,MECOM,CDKN2C,CCNA2,KIF14,RANBP1,FUT8,PRC1,NEK2,KIF22,KNTC1,RNASEH2A,MSH6,SMC4,MDFI,ZWINT,SHMT1,NUSAP1,YES1,POLD3,CDC25C,H2AFV,CDK1,PRIM1,AURKA,CENPE,NRGN,SEMA3A,UBE2C,ESPL1 |
| 1.607e-05 | -11.04 | condensed nuclear chromosome, centromeric region | cellular component | GO:0000780 | 19 | 11 | 17570 | 2579 |
PLK1,REC8,CENPA,KMT5C,CENPC,NDC80,AURKA,BUB1,AURKB,CCNB1,SGOL1 |
| 1.613e-05 | -11.03 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | 481 | 104 | 17758 | 2588 |
LZTFL1,SLC35D2,BCAM,PAPSS2,HDAC11,FHDC1,KCTD12,TEX2,EGR3,SNN,FAM46C,TACC2,DDHD2,SLC44A1,RGS5,EPB41L4B,TMEM64,RCAN3,SCARA3,CPE,NEB,SMARCA2,PFKFB2,SNTB2,SH3BGRL,SYNE2,TNS1,SLC17A5,KCTD2,PNKD,SESN1,ENPP1,TMEM164,SLC25A4,TTC12,ANKRD6,WFS1,LRIG1,GLCCI1,CHPT1,STARD13,ST3GAL1,LIFR,CBX7,MAMDC2,PRKAR1A,RRAGD,ZMAT1,GLIS3,WASF3,PINK1,PLSCR4,FARP1,TBC1D1,ZCCHC24,CTSB,SLC25A27,ASAH1,AKAP17A,ARHGEF40,GSTP1,PARM1,NEO1,CCDC92,MLPH,FRY,FLRT3,FBXO7,RRBP1,PRKG1,SORL1,SGK1,ACTA2,KLF9,MYLIP,ALDH3A2,HES1,PHF20L1,WDR72,TEF,TMEM133,CYFIP2,FOS,GLT8D2,FRMD4B,GNAS,FECH,ARHGAP24,TMEM50B,CACHD1,BANK1,TIMP3,SLC4A4,MATN2,ITPR1,CSGALNACT1,NR4A2,SH3BGRL2,FHL1,ZMIZ1,NDFIP1,TOB1,CYBRD1,PKIA |
| 1.617e-05 | -11.03 | BASAKI_YBX1_TARGETS_DN | MSigDB lists | BASAKI_YBX1_TARGETS_DN | 359 | 82 | 17758 | 2588 |
PNISR,PAPSS2,IBTK,CRYM,NDRG1,TSC22D3,DNAJC3,CUL4B,SLC20A1,PHLDA1,SYTL2,CDH1,IL6ST,TSPAN6,PLCG2,SLC44A1,TMEM37,TSPAN1,LMAN1,LAMP2,SMARCA2,CD55,LGALS8,SEPT6,SAT1,CYS1,RBM47,DHRS13,CDK19,PTER,FAM110C,SLC27A1,NFKBIZ,GLCCI1,RAP1GAP,MAFF,RRAGD,IER5L,HLA-E,ETV5,SLC25A27,GDF15,SEPP1,DHRS3,DUSP5,SLC25A36,SPP1,CARD8,FAM189A1,MGAT4A,ALG13,FLRT3,AIM1,MAST4,SPRY2,TPCN1,SLC45A3,SPATA20,HES1,ZC3H11A,PIK3R1,ZNF320,BTN3A2,AK4,STMN3,RAB3IP,PDK3,SNTB1,ANTXR1,FOS,ANKRD29,GALNT3,BTG1,SERPINA1,PLOD2,PAPD5,TMC5,FAM3C,ARRB1,PKD2,JAK3,SERPINB1 |
| 1.625e-05 | -11.03 | early endosome | cellular component | GO:0005769 | 287 | 69 | 17570 | 2579 |
NF2,GPR107,EPHA4,RET,MVB12B,DNER,ZFYVE9,ZFYVE16,RABEP2,STEAP2,SNX16,RAB20,ECE1,F2R,SNX8,CLCN3,VPS11,KREMEN2,RNF11,SLC11A2,RAB38,SNX12,SLC9A6,ARF6,F2RL1,PACSIN2,SORT1,HLA-F,HLA-E,ATP9A,FLOT1,CNTNAP2,FAM21C,HLA-A,VPS26A,PARM1,MARCH8,SNX13,WDFY1,OCRL,KIAA0319,SGK3,SORL1,TRIM3,HLA-C,WNT3A,PIKFYVE,MYO5A,TRAK2,DIAPH2,NEURL1B,FAM109A,RHOB,EGFR,HLA-B,AP1AR,NUCB1,LDLRAP1,CTNS,PRDX3,RIN3,APPL2,RAB31,DYSF,GPER1,FZD5,RUSC1,NIPA1,EHD1 |
| 1.683e-05 | -10.99 | MODULE_456 | MSigDB lists | MODULE_456 | 108 | 33 | 17758 | 2588 |
CCNE2,FAM169A,TRIB2,DUSP5,TSPAN7,CDKN2C,PCNA,BMP7,IL6ST,A4GALT,BCL6,SORL1,IFIT1,OAS3,NFKB2,MYBL1,GCC2,MMD,STAT4,PTGER4,CR2,PRKAR2B,SRSF5,PIF1,ASB13,POLD3,CD83,CD8A,SWAP70,FYN,PTK7,NFKBIA,NR4A3 |
| 1.719e-05 | -10.97 | Signalling to ERKs | REACTOME pathways | R-HSA-187687 | 246 | 62 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,RALB,SHC3,PSMC2,DUSP10,MAPK11,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,MAPKAPK3,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,MAPKAPK2,IRS2,PLCG1,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,MAPK13,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D,MAPK12 |
| 1.744e-05 | -10.96 | REGULATION_OF_PROTEIN_KINASE_ACTIVITY | MSigDB lists | REGULATION_OF_PROTEIN_KINASE_ACTIVITY | 151 | 42 | 17758 | 2588 |
CCNE2,SPRED1,TAOK2,CDKN1C,TRAF2,ERBB2,HERC5,PKN1,TRIB2,CARD10,PICK1,CCND1,CDKN2C,DIRAS3,RB1,IRAK1,PTEN,RGS3,PAK2,MAP3K9,CKS1B,MDFIC,HEXIM2,MAP3K7,CDKN2D,CCDC88A,CKS2,MDFI,SOD1,STRADB,PKMYT1,CDC25C,MAP3K6,EGFR,CDK5R1,CDK5RAP1,MADD,KIAA1804,MAP3K11,MAP3K5,CD81,HIPK3 |
| 1.759e-05 | -10.95 | Fc receptor signaling pathway | biological process | GO:0038093 | 357 | 83 | 16441 | 2455 |
SPRED1,PSME2,CUL1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PDGFB,SPTB,PDGFA,CALM2,PSMD1,ELMO2,SHC3,PSMC2,PLCG2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKCQ,ITPR3,IRS2,PLCG1,FYN,JAK1,LIMK1,PSMD3,SPTBN5,NRG1,GAB1,PSMC1,TNRC6C,TAB3,RASA2,PSMD7,PSMD10,CALM3,PLD2,TEC,NCKAP1,PHLPP1,FGF19,DUSP5,PTEN,PAK2,ERBB3,MAP3K7,NCAM1,SYK,PSMA5,CAMK2G,RASGRF1,PSMB4,NR4A1,RAPGEF2,CALM1,PIK3R1,GRIN1,YES1,CYFIP2,FOS,PSMA4,RASA1,EGFR,BCL10,FGFR2,PHLPP2,FGF18,ITPR1,NFKBIA,UBE2D2,NR4A3,GRIN2D,ARPC2,JAK3 |
| 1.759e-05 | -10.95 | plasma membrane region | cellular component | GO:0098590 | 906 | 178 | 17570 | 2579 |
GRIK2,EPHA4,SYTL4,HDAC6,PJA2,PDGFB,SLC9A3R2,NCS1,PICK1,EPCAM,CTNNB1,CDKL5,CABP1,SLC46A1,DLG1,DNM2,CLDN4,TRPC1,TACSTD2,RP2,PACSIN1,MYRIP,CPE,SGCE,MGAM,EZR,ARF4,LCP1,ENPP1,GRID2IP,KCNK1,ATP7B,NOD2,PRKCDBP,PIEZO1,SPRY4,ARF6,LZTS1,DDX58,SCN5A,BVES,ITGA6,PRKAA1,CNTNAP2,SLC1A3,NCKAP1,DHRS3,ANO1,VASP,CA2,ITGA3,IGF1R,ZNRF2,FLRT3,KCNN4,PRKCI,NPTN,CNGA1,SLC12A2,RIMS2,GPR161,ABCC1,EPB41L5,SPATA13,SCRIB,ANTXR1,STX3,EGFR,RASGRP2,GABRD,INSR,TJP3,SLC4A4,TMEM30A,PHLPP2,OSMR,STK39,OSCP1,PLD1,MAL2,ATP1B3,SHROOM2,RUSC1,DRD1,PROM2,EHD1,SPRED1,NF2,TCTN2,ST14,ERBB2,KCTD12,APC2,PRKACA,EMP2,PRR7,EPS8L2,CD46,SCNN1A,CDH1,SMO,CNNM4,PDE4D,RAB27B,DLG3,F2R,FLOT2,DMTN,SYNE2,CYS1,UTRN,CLSTN1,SLC11A2,SYP,ATP1B1,ERBB2IP,CBL,TANC1,DAG1,GABARAPL1,DUOX1,PTGS2,PTPRJ,ATP1A1,SHROOM3,STK26,CORO1C,SIPA1L1,SLC27A1,SPTBN5,NRG1,EFNA5,RGS14,PRKAR1A,TTC8,PACSIN2,CTSB,LRP4,EPS8,FLOT1,GABRG2,PLD2,SRPX2,FZD6,SNTA1,ANK1,ADORA1,PTEN,ANKS1B,MAGEE1,CD9,ATP8B1,IGFBP2,ERBB3,SPRY2,DLGAP1,AMOTL2,ADAM17,RHOA,CASK,CRB3,RAPGEF2,PLAUR,GRIN1,VAMP3,AIF1L,BBS2,PROM1,LDLRAP1,ARRB1,GRIN2D,PKD2,GPER1,ITGAV,L1CAM,CYBRD1,OCLN,ARHGEF4 |
| 1.769e-05 | -10.94 | DORN_ADENOVIRUS_INFECTION_48HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_48HR_DN | 40 | 17 | 17758 | 2588 |
NR4A1,FHL2,COL7A1,SRSF5,EGR3,CD83,IER3,CCND1,BCAR3,RND3,CYR61,PLK2,NFKBIA,SGK1,SERPINB5,TNFRSF12A,EFNA1 |
| 1.769e-05 | -10.94 | YU_MYC_TARGETS_UP | MSigDB lists | YU_MYC_TARGETS_UP | 40 | 17 | 17758 | 2588 |
PLK1,TXN,KIF20A,ASPM,RACGAP1,CCNB1,ANLN,CDK1,TOP2A,PCNA,AURKA,CKS1B,KPNA2,BUB1,CCNB2,E2F8,CKS2 |
| 1.777e-05 | -10.94 | CSR_LATE_UP.V1_DN | MSigDB lists | CSR_LATE_UP.V1_DN | 156 | 43 | 17758 | 2588 |
CDS2,NFKBIE,FAM131C,PYROXD2,TSC22D3,SOD2,FTH1,CHST2,KIAA1147,SCML1,NOV,ITGB8,SNX18,CALD1,FDXR,DRAM1,PRKG1,PRKCI,NTN4,C10orf54,IGDCC4,OLFML2A,P2RX4,FADS2,DDB2,ADAM17,C6orf1,ERMP1,BTBD19,PDE5A,DUSP4,SNTB1,GLT8D2,ANKRD29,POR,BCL10,IRS2,PGF,ACVRL1,LRIG1,RCAN2,L1CAM,MAMDC2 |
| 1.784e-05 | -10.93 | REACTOME_SEMAPHORIN_INTERACTIONS | MSigDB lists | REACTOME_SEMAPHORIN_INTERACTIONS | 64 | 23 | 17758 | 2588 |
MYL9,DPYSL5,RHOA,ARHGEF11,ERBB2,PLXNA1,DPYSL4,RHOB,CDK5R1,RND1,DPYSL3,ARHGAP35,RAC2,FYN,SEMA4D,DPYSL2,LIMK1,PAK2,PLXND1,MYH14,SEMA3A,MYL12B,FARP2 |
| 1.797e-05 | -10.93 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP | 196 | 51 | 17758 | 2588 |
PLA2G4A,COL9A3,SPRED1,TTC39B,FAM129B,EPS8,MCOLN3,PDIA5,FAM101B,IL18R1,EPDR1,CCND1,FAM111A,ADD3,ARL1,CD9,GYS1,NFU1,HLA-C,TTPA,IL10RB,C9orf72,TMBIM1,TSPAN33,CKAP4,IGDCC4,CERS2,SOCS5,SYPL1,PLSCR1,GCLC,VAMP3,GGH,PCTP,STX3,NFIX,IDE,LDLRAP1,SWAP70,FASTKD1,PRCP,NIPSNAP3A,CDCA7L,PLA2G15,PRDM5,APPL2,LRRK1,TTC39C,CD81,SERPINB1,CD33 |
| 1.797e-05 | -10.93 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | 196 | 51 | 17758 | 2588 |
GRN,GAA,LGALS3,CTSB,BLVRB,HEXB,ASAH1,KCTD12,IL13RA1,DSE,ARHGEF40,SIRPA,APLP2,ATP6V0B,TNS3,PLCG2,CST3,DAPK1,CTSD,SNX10,NAGA,SYK,GM2A,CKAP4,CYP1B1,GCA,TIMP2,ALDH2,MPP1,PLAUR,ERP44,C15orf39,RNPEP,ADRBK2,TP53I3,CRISPLD2,TMEM164,ALDH3B1,RBM47,SERPINA1,CORO1C,SLC2A6,SECTM1,RAB31,ZDHHC7,CLMN,CTSA,GLA,PLIN3,SLC31A2,SLC27A3 |
| 1.799e-05 | -10.93 | DH_2 | prosite domains | PS50010 | 70 | 25 | 11866 | 1802 |
PLEKHG3,RASGRF1,ARHGEF28,ARHGEF3,FARP1,ARHGEF11,ARHGEF7,SPATA13,ARHGEF40,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,MCF2L,PLEKHG1,FGD6,TIAM1,ARHGEF9,NGEF,ARHGEF4,FGD1,FARP2 |
| 1.800e-05 | -10.93 | response to fibroblast growth factor | biological process | GO:0071774 | 320 | 76 | 16441 | 2455 |
SPRED1,PSME2,IQGAP1,NRG2,ERBB2,RASGRP3,PSME1,ITPR2,EGR3,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,CTGF,SHC3,PSMC2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,CBL,ITPR3,IRS2,PLCG1,FYN,JAK1,PSMD3,TBX1,SPTBN5,NRG1,PSMC1,GAB1,PRKAR1A,TNRC6C,RUNX2,RASA2,PSMD7,PSMD10,CALM3,PHLPP1,FGF19,DUSP5,ADRBK1,PTEN,FLRT3,ERBB3,NCAM1,SPRY2,CAMK2G,PSMA5,RASGRF1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,ELK1,PSMA4,EGFR,RASA1,FGFR2,PHLPP2,ITPR1,FGF18,GRIN2D,JAK3 |
| 1.800e-05 | -10.93 | MARTINEZ_RB1_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_TARGETS_UP | 648 | 133 | 17758 | 2588 |
ADD1,DNAJC3,SLC25A13,PNPLA2,SH3KBP1,WEE1,TGFBR3,ZFP36,IL6ST,KLF3,DNM2,ABCA2,TECR,PTPRE,PLK1,CENPA,PBK,ACBD3,USP18,RAB2B,LCP1,DPYSL3,HOXA9,BMP1,TMOD2,CHPT1,CD99,RECQL,LASP1,INPPL1,MRC2,HJURP,SCOC,SOX9,RACGAP1,RAB6A,FAM21C,FBLN1,TNFRSF19,TIMP1,CYR61,BRAT1,NTN1,EPHX1,QSOX1,FADS2,KIF20A,FHL2,TCF7,BCL2L13,NUBP1,RANBP9,EGFR,FRMD4B,FECH,GNAS,PTPRF,RAB31,DCUN1D1,PLD1,MAP3K5,RARG,SNX30,XDH,RAD21,SORBS1,SLC2A4,TP53,OSR2,CCNL1,EMP2,DDR1,BCAP31,IER3,CCND1,APLP2,FRYL,CDH3,RPN2,LMAN1,ETHE1,SULT2B1,CTDSP2,CPD,MYO5B,CLCN3,COL6A2,CAPN6,ACO1,GLO1,SLC11A2,PTGS2,IDE,JAK1,OVOL1,SLC25A30,PINK1,PCOLCE,CTSB,MAN1A2,ERI2,COL4A5,RBP7,EFNB1,HOXB2,SIRPA,LGALS3BP,SGPL1,TMCC3,ADD3,FUT2,CALD1,DRAM1,AK3,DUSP1,FAH,SHMT1,ZC3H11A,NR3C1,NR4A1,GCLC,ELOVL3,AIF1L,KIF11,MAP1B,FUCA1,TIMP3,DGCR2,CTNS,FGFR2,TWSG1,ITGAV,HIPK3 |
| 1.802e-05 | -10.92 | CDKN1C (cyclin-dependent kinase inhibitor 1C (p57, Kip2)) | protein interactions | 1028 | 21 | 12 | 16036 | 2547 |
CCNE2,CCND1,RB1,PCNA,CCNA2,AKT1,RBL1,LIMK1,MYBL2,PIAS2,NR4A2,CDK1 |
| 1.808e-05 | -10.92 | response to hormone | biological process | GO:0009725 | 1003 | 197 | 16441 | 2455 |
CASP3,UGT8,TRIM24,NRG2,GATA3,PSME1,PDGFB,SDC1,SPTB,CALM2,SESN3,PSMD1,TGFBR3,CTNNB1,CTGF,SHC3,PSMC2,FOSB,STEAP2,PIK3CA,ABCA2,AKR1B1,CLDN4,ASH2L,ARNT2,RASGRP1,THRB,CITED4,ACVR1C,CASP9,PRKAR2B,IDH1,POR,RHEB,PIAS3,MDK,ENPP1,MAP2,AREG,CAB39,EIF4EBP2,ADIPOR1,PSMC1,GAB1,NR2C2,RRAGD,PRKAA2,GRN,INPPL1,RASA2,PRKAA1,PSMD7,ATP6V1E2,CALM3,DUSP5,TFAP4,CALR,SPP1,ITGA3,TIMP1,CA2,IGF1R,PRKCI,NCAM1,PSMA5,PAQR7,CALM1,FHL2,STRADB,ELK1,KDM3A,PSMA4,EGFR,RASA1,FAS,GNAS,FECH,MMP15,TSC1,NCOA3,PRKAG2,INSR,RAB31,AURKA,NR4A2,JAK3,RARG,DRD1,GAS2L1,SPRED1,SORBS1,SLC2A4,NQO1,FOXM1,THRA,SLC2A8,PSME2,WDTC1,ERBB2,RASGRP3,PRKACA,GNB2,PDGFA,CCND1,ATP6V0B,CCNA2,CDKN1B,DAB2IP,GOT1,RASGEF1A,NR2C1,FRS3,SIRT1,TIMP2,AKT1,PTPRU,PRKCQ,DAG1,SOCS3,IRS2,PTGS2,FYN,IDE,ATP1A1,JAK1,PSMD3,STAT1,SLC27A1,NRG1,SPTBN5,LTA4H,NR3C2,PRKAR1A,ANXA3,NKX3-1,SORT1,CTSB,SERPINB9,PSMD10,ETS1,FGF19,ICAM1,HDAC9,OXCT1,PTEN,BMP7,CST3,TOX2,BAX,IGFBP2,KLF9,ERBB3,CITED2,CAMK2G,MYO5A,NCOA2,GCNT1,DUSP1,RASGRF1,ADAM17,RHOA,PSMB4,WNT10B,NR3C1,RAPGEF2,NR4A1,GCLC,PIK3R1,GRIN1,PPARA,GGH,YES1,FOS,BBS2,BCAR1,GPLD1,CTSL,PITX2,BTG1,RGS9,TIMP3,PLOD2,FGFR2,NR1D2,CTSV,FGF18,NR4A3,GRIN2D,GPER1,HOXB13,ATP6V1C1,PLOD3,ARSB,TBC1D4,CPEB2,FOXA1,ABCG1 |
| 1.814e-05 | -10.92 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | 191 | 50 | 17758 | 2588 |
GRN,SORT1,RUNX2,CD63,NDRG1,HEXB,EFHD2,NDRG2,KCTD12,IL13RA1,IL18,MGST2,GSTP1,FLT3,SIRPA,ICAM1,LMNA,TIMP1,DPYSL2,CST3,PRKCI,DAPK1,H2AFY,APIP,ETHE1,PTPRE,PLCB2,TIPARP,NAGA,PPIF,PGM1,MCTP1,ALDH2,TMEM43,MAPKAPK3,S100A4,ATP1B1,DOCK5,SLC25A5,STX3,INSR,ETS2,RIN3,SH3BP4,RAB31,ARRB1,NDFIP1,TOB1,AHR,CD33 |
| 1.814e-05 | -10.92 | GSE30083_SP2_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP2_VS_SP4_THYMOCYTE_DN | 191 | 50 | 17758 | 2588 |
GRN,TTC39B,ST14,PPM1J,ITGA6,MCTP2,SDC4,TAP1,FAM78A,DSE,CDIPT,FAM101B,FAM46C,IL18R1,FAM167A,CCND1,CDH1,FAM46A,KLF3,SGK1,IL17RA,IFIT1,SNX10,ALS2CL,GM2A,FAM69A,PQLC3,STAT4,CORO2A,SNTB2,SYNE2,IFIT3,ATP10D,RHOB,SOCS3,ENDOD1,HLA-B,LDLRAP1,HPSE,MADD,APPL2,HS3ST3B1,GEM,MAP3K5,TTC39C,ARSB,F2RL1,TRAF5,XDH,NXT2 |
| 1.814e-05 | -10.92 | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP | 191 | 50 | 17758 | 2588 |
FRMD6,DDIT4L,THRA,TSC22D3,ABCG2,IL27RA,HMGN3,SYTL4,M6PR,ZFYVE16,RCN1,ZFX,RNF220,IRAK1,PTEN,TACC2,DDHD2,SLC44A1,FXYD5,MDFIC,TNFRSF18,EPB41L4B,HLA-C,DGKG,TIPARP,SLC35A1,CERS2,P2RX4,SUN2,SHMT1,NR3C1,TEF,PTGER4,TNS1,ERBB2IP,ALCAM,STK17B,NFIX,HLA-B,TAPBP,NT5C2,NR1D2,PELI2,PRDM5,FAM117A,RPL22,ISOC1,GAB1,IRF1,FGD1 |
| 1.819e-05 | -10.91 | Extracellular matrix organization | REACTOME pathways | R-HSA-1474244 | 267 | 66 | 8202 | 1235 |
CASP3,LTBP1,AGRN,HSPG2,P3H2,COL18A1,F11R,SDC1,DDR1,PDGFB,LTBP3,PDGFA,CDH1,P4HB,NTN4,LOXL1,COL6A2,TIMP2,LOXL2,DAG1,COL12A1,MMP17,BMP1,ADAMTS14,CAPN1,COL9A3,PCOLCE,ITGA6,CTSB,LRP4,SDC4,COL4A5,FBLN1,ICAM1,ITGA2B,BMP2,SPP1,TIMP1,ITGB8,ITGA3,BMP7,COL6A1,ADAM15,CTSD,NCAM1,CRTAP,ADAMTS2,ADAM17,CASK,FBLN5,FURIN,COL7A1,CAPNS1,CTSL,MMP15,COL13A1,PLOD2,ITGA7,CTSV,KLK7,ITGAV,LTBP2,PLOD3,COL16A1,ADAMTS16,TLL2 |
| 1.831e-05 | -10.91 | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | 171 | 46 | 17758 | 2588 |
TXN,DYRK3,IL15RA,ELOVL7,SDC4,SOD2,IL18,CD274,SNX9,TNFSF9,DUSP5,ICAM1,RND1,IER3,OTUD1,E2F7,PIK3AP1,FJX1,DRAM1,UBE2J1,SELK,RPGR,ATP2B1,LAMP3,DUSP1,P2RX4,B3GNT2,RIPK2,PLAUR,STAT4,RAPGEF2,MGAM,PIM3,SAV1,CDK1,CD83,SOCS3,PTGS2,ETS2,AREG,MFSD2A,NFKBIA,NFKBIZ,PLD1,GEM,MAFF |
| 1.833e-05 | -10.91 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | 181 | 48 | 17758 | 2588 |
DDX58,PARP12,IL15,TMEM217,PARP14,TRIM5,ARHGEF11,TAP1,HERC5,GPR180,PDGFRL,SAMD9,CD274,HERC6,DUSP5,HPCAL4,LGALS3BP,DTX3L,FAM46A,GRHL1,TRIM21,IFIT1,OAS3,MYBL1,GAD1,ETV7,APOBEC3G,PARP9,MX1,AMOTL2,PLSCR1,IFITM3,PAPD7,USP18,IFIT3,ZNF618,PTGS2,PI4K2B,C19orf66,SEMA4D,SECTM1,NLRC5,IRF7,CMPK2,SLC31A2,IFIH1,IFI6,IRF1 |
| 1.835e-05 | -10.91 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN | 176 | 47 | 17758 | 2588 |
DDX58,UNC93B1,IL15RA,PARP14,TRIM5,TAP1,UBE2Z,HERC5,GPR180,SAMD9,CD274,HERC6,PGAP1,LGALS3BP,DTX3L,CCNA2,FAM46A,SP100,TRANK1,ELMO2,TRIM21,IFIT1,OAS3,ETV7,APOBEC3G,PARP9,MX1,AMOTL2,PLSCR1,LAP3,MICB,USP18,IFIT3,PI4K2B,C19orf66,TRIM69,SEMA4D,SECTM1,STAT1,NLRC5,IRF7,CMPK2,IFIH1,SLC31A2,IFI6,IRF1,HS6ST3 |
| 1.859e-05 | -10.89 | cellular response to fibroblast growth factor stimulus | biological process | GO:0044344 | 315 | 75 | 16441 | 2455 |
SPRED1,PSME2,IQGAP1,NRG2,ERBB2,RASGRP3,PSME1,ITPR2,EGR3,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,CTGF,SHC3,PSMC2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,CASP9,AGO4,PRKAR2B,CBL,ITPR3,IRS2,PLCG1,FYN,JAK1,PSMD3,TBX1,SPTBN5,NRG1,PSMC1,GAB1,PRKAR1A,TNRC6C,RUNX2,RASA2,PSMD7,PSMD10,CALM3,PHLPP1,FGF19,DUSP5,ADRBK1,PTEN,FLRT3,ERBB3,NCAM1,SPRY2,CAMK2G,PSMA5,RASGRF1,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PSMA4,EGFR,RASA1,FGFR2,PHLPP2,ITPR1,FGF18,GRIN2D,JAK3 |
| 1.897e-05 | -10.87 | ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN | MSigDB lists | ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN | 44 | 18 | 17758 | 2588 |
ARHGAP11A,SPC25,DEPDC1,FOXM1,CDC20,ERCC6L,MYBL2,WHSC1,KBTBD8,AURKB,CCNB1,CDK1,TOP2A,CCNA2,RANBP1,PLK4,AURKA,CKS1B |
| 1.918e-05 | -10.86 | centrosome | cellular component | GO:0005813 | 474 | 103 | 17570 | 2579 |
DYNLRB1,SORBS1,CEP70,DLGAP5,ACTR8,NDRG1,NDRG2,CNTROB,BCL2L1,SYTL4,ZMYND10,CCNB1,PRKACA,STIL,CALM2,LRRC45,PCNA,CTNNB1,CNTRL,CEP78,CAPG,PLK4,DNM2,TUBG1,HYLS1,RP2,PDE4D,SNX10,ODF2L,CCDC38,PLK1,CAMSAP3,PCGF5,FOPNL,UXT,CCSAP,CDC20,VPS4B,CKAP2L,PRKAR2B,KIF13A,AURKB,CCNF,CDK1,NIN,CEP162,DZIP1L,CAMK2N2,STK26,PLK2,TRAF3IP1,MAP3K11,RGS14,SGOL1,GEN1,TRAF5,TTC8,MZT1,PPP1R12A,CKAP2,POC1B,FLOT1,ERCC6L,CALM3,KIF23,TXNDC9,IFT27,SSX2IP,CKAP5,TOP2A,CCDC92,MZT2A,TBC1D31,CEP97,CENPJ,TUBGCP6,NEK2,TFAP2A,SLAIN2,RPGR,MPHOSPH9,CEP89,B9D2,CALM1,RGCC,PLEKHA7,KIF20B,RAB3IP,NUBP1,MAPKAPK2,DCTN6,HTT,AURKA,MDH1,PPP2R3C,SSNA1,NDE1,WDR62,CFAP20,CEP41,CCNB2,ESPL1,DIS3L |
| 1.941e-05 | -10.85 | AMIT_SERUM_RESPONSE_60_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_60_MCF10A | 56 | 21 | 17758 | 2588 |
TGIF1,PTGER4,EGR3,DUSP5,C1orf116,RHOB,FRMD4B,MAGED2,IRS2,PTGS2,ETS2,CTGF,CYR61,CALD1,PLK2,BMP1,SGK1,NR4A2,PXMP4,CYBRD1,KLF7 |
| 1.951e-05 | -10.84 | ZHANG_TLX_TARGETS_36HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_36HR_UP | 217 | 55 | 17758 | 2588 |
CDS2,SORT1,TM2D2,SORBS1,PINK1,LFNG,S100A11,PNPLA2,TAP1,EMP2,SIRPA,PDGFA,OPN3,AOX1,DNM2,BAX,SLC44A2,ADAM15,TNPO2,TAX1BP3,PLEKHF1,ARNT2,CITED2,NFKB2,PTPRE,CTDSP2,TTLL1,DVL2,EPHX1,IGDCC4,P2RX4,POU6F1,QSOX1,TIMP2,PQLC3,NR4A1,S100A4,TEF,SAT1,PIP4K2C,TNS1,TYSND1,MAPK8IP1,TCN2,GABARAPL1,BTG1,SCARB2,TAPBP,CSF1,CLIP4,OTUB2,SPRY4,CBX5,TOB1,CPPED1 |
| 1.962e-05 | -10.84 | BROWNE_HCMV_INFECTION_2HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_2HR_DN | 48 | 19 | 17758 | 2588 |
RAB3B,CENPA,CYP2J2,PLAUR,ITGA6,KIF23,PHLDA1,DGKE,RAD23A,ITGA3,COL13A1,AXL,PAK2,CDKN1B,SGK1,CENPE,TTC9,UBE2C,ABCC1 |
| 2.019e-05 | -10.81 | organelle organization | biological process | GO:0006996 | 3164 | 548 | 16441 | 2455 |
DOC2A,ADD1,MRPS15,AK7,PNPLA2,HEXB,XIAP,CCNO,TRAPPC8,CNTROB,MORF4L2,SYTL4,SNX9,PHF1,NPM2,WEE1,ZYX,PHYHIP,TUBG1,TUBA4A,DNAAF3,NEK4,SPEF2,VPS11,SMARCA2,DSTN,UXT,MTRF1L,PRKAR2B,LOXL2,MYOM1,ARF4,GINS4,LCP1,ABR,DNM1L,LIMK1,TRAF3IP1,MYLK,HDAC1,MRPS28,TMOD2,ITPKA,ARF6,SOX9,RAB23,GPSM2,LMNA,ATG4A,FLII,RAC2,ZCCHC17,FRY,RIMS3,FBXO7,FAM13B,NEK2,SLAIN2,ALPK1,NUP85,TTLL1,PPP6R1,NAGPA,REC8,HPS3,KIF20A,SHARPIN,MYBL2,PLS1,KIF20B,NPHP3,TP53INP2,PLIN5,NCOA3,MTFMT,TIMM8A,HTT,SETD3,TEX30,AURKA,DYSF,MDH1,NDE1,ARPC2,NUP58,DMPK,MTM1,TMSB15A,LFNG,TUBB4B,ACTR8,APOO,PTTG1,TESK2,PKP2,NUF2,PRKACA,CCND1,SP100,SNX10,SNX8,CAMSAP3,PSRC1,SYNE2,CYS1,VPS4B,SYP,CDCA2,NUSAP1,RAB38,SNX12,COX20,GABARAPL1,PEX5,PDLIM3,SHROOM3,CORO1C,SIPA1L1,RGS14,MAPK12,TTC8,TAOK2,HSP90B1,BIK,CTSZ,PKN1,ETS1,IFT27,DTX3L,ANK1,PDCD10,CTSC,FAM160A2,TUBGCP6,BAX,PLEKHF1,MAPK11,RAG1,ACBD5,LCA5,TACC1,FMN1,UBE2A,RAB3IP,FAM109A,SKA1,ABLIM2,CNTNAP1,RPL12,PLOD2,ATXN7L3,SYT7,SLC35B3,SSNA1,HMGA1,CENPE,NUP37,WDR45B,FOXA1,PHC1,EPAS1,CUL4B,SUDS3,ARFGEF1,LMCD1,NDC80,F11R,HDAC6,INPP5E,PCNA,NUP210,CTNNB1,CNTRL,ARL1,TLN2,ZNF462,PLK1,MARK1,ING1,CELSR2,CBX6,C12orf65,EZR,ANLN,CDK1,OPTN,DPYSL3,KDM4D,DZIP1L,MSL1,MAP2,WIPI1,PRKCDBP,TC2N,PRKAA2,USH1C,HJURP,SORBS3,RACGAP1,NCKAP1,SSX2IP,CORO1B,RB1,VASP,PAK2,FCHO1,TBCD,EXOC8,CYP26B1,MRPS33,CORO2A,STRADB,H1F0,PVRL2,CCNB2,CDAN1,CTBP1,IFI6,RAD21,NF2,TP53,P2RX7,BAHD1,EMP2,STIL,TMSB15B,SYTL2,PER2,TTC21B,PDGFA,ATP6V0B,KMT5C,SRPX,TACC2,BCL6,PLK4,ESPN,LMAN1,SIRT1,PPIF,CLCN3,AKT1,FIGNL1,CDC20,DAG1,RBL1,PTK7,CHMP4B,XRCC3,SYT13,ARHGAP4,CNEP1R1,ZC3HC1,COPG1,FAM134B,PINK1,PACSIN2,TRAPPC10,KLHL13,CDCA8,ERCC6L,HMGN3,AIP,H1FX,CEP97,BUB1,HMGCL,ABCD1,RHOA,HMGN5,NR3C1,STMN3,COL7A1,BCAR1,BORA,BBS2,SERPINA1,PPP2R3C,PKD2,UBE2C,GOLGB1,SUN1,GAA,CFAP74,SSH1,SEPT4,CCNB1,FAM101B,CENPN,PAK6,TYMP,ELMO2,PIK3CA,PACSIN1,TFG,SPATA18,PBK,CDYL,BNIP3L,SLC35C1,KIF13A,AURKB,PIF1,MCFD2,CCNF,ULK2,PRIM1,SLC25A4,AREG,GNPTAB,PLK2,PPP2R4,PRDM5,RTN3,FGD1,RECQL,MRPL44,INPPL1,PRKAA1,KIF23,SLC1A3,MECOM,CALR,DOPEY2,SNX18,PRKG1,MSH2,MAST4,SYTL3,TMED2,DNAI1,EPB41L5,GCC2,DDB2,PMPCB,B9D2,CEP89,WHSC1,ATP8B3,JADE2,ANTXR1,KDM3A,PRKAG2,FAM64A,WDR19,ARAP1,FAM83D,FGD6,SFMBT1,CABIN1,HOOK1,EHD1,ELK4,KIF3C,TCTN2,DLGAP5,CEP70,TRIP10,SUZ12,BCL2L1,AIFM2,MNS1,CCNA2,GPX4,ATG4D,SEC23A,TMEM43,CAPN6,COG2,DMTN,TEP1,PKMYT1,PYGO1,ATP1B1,AKR1E2,H2AFV,ZMPSTE24,CEP162,NIN,TRIOBP,RAB29,COBL,CBX7,PRKAR1A,MRPS9,WASF3,CENPI,EPS8,CDCA3,PLD2,SPDL1,SIX4,CKAP5,SLC25A36,RND1,PTEN,CENPJ,PRC1,ATP8B1,ERCC2,MAP3K7,SPRY2,MSH6,NCOA2,SMC4,FARP2,ARHGEF28,ZWINT,PAPD7,VAMP3,DIAPH2,KIF11,DCTN6,CRTC2,PRDX3,GPER1,WDR62,ARSB,NCAPG2,ESPL1,USP16,JARID2,FAF2,UGT8,TAF6L,KIF2C,MAP1LC3B,SH3KBP1,ZFYVE16,LRRC6,DPYSL2,CEP78,DLG1,ASH2L,RAB20,KIF22,SUN3,RP2,CTTN,MYH14,ATL1,SOD1,CENPA,SYNE3,ASXL1,STRIP2,FOPNL,ARHGDIB,MRPS18A,MRPS36,PTGFRN,IARS2,NR2C2,ARAP3,PPP1R12A,SERPINE2,PEX6,ATP6V1E2,OCRL,PRKCI,LIMCH1,KNTC1,ZRANB1,ALS2CL,HP1BP3,SNX7,FBXO8,HMG20B,RANBP9,ONECUT1,CDCA5,PAPD5,RAB31,SHROOM2,SNX30,FBXW5,GAS2L1,DYNLRB1,LZTFL1,SORBS1,SPC25,SLC2A8,HDAC11,SOD2,TDRKH,MRAS,ZMYND10,PATL2,MICALL2,SAP130,SS18,SETDB2,COX14,FRYL,KIF14,REEP1,EPB41L4B,F2R,HSPA2,CHP1,CKS2,TAF5,MRPS35,ERBB2IP,CDC25C,HSF4,JADE1,PEX2,SPTBN5,SGOL1,REEP4,PPP2R2D,ABCA1,CBX4,GCLM,SORT1,ARHGEF11,POC1B,ARHGEF7,CIT,SHPRH,SH3D19,HMGXB4,SAC3D1,HDAC9,TOP2A,KIF5B,LLGL2,TOX2,H2AFY,RPGR,SUN2,CENPC,CFAP46,GCLC,ASPM,POLD3,MPV17L2,SPAG1,MAP1B,LEMD2,SWAP70,RND3,TADA2B,ARRB1,GEM,CEP41,ATP6V1C1 |
| 2.025e-05 | -10.81 | positive regulation of locomotion | biological process | GO:0040017 | 396 | 90 | 16441 | 2455 |
ACVR1,ATP8A1,RET,COL18A1,GATA3,CD274,CAMK1D,HDAC6,PDGFB,PDGFA,EPCAM,DAPK2,ARTN,P4HB,TNFRSF18,DAB2IP,TWIST1,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,SEMA3B,DOCK4,BAG4,AKT1,DMTN,SYNE2,DOCK5,IRS2,PTGS2,PLCG1,MYLK,FAM110C,HSPB1,F2RL1,SEMA6B,ANXA3,LGALS3,BVES,ARHGEF7,SOX9,SELL,CBLL1,ETS1,FBLN1,SRPX2,ICAM1,NRP2,ITGA2B,HDAC9,CALR,BMP2,RAC2,CXCL16,PDCD10,ITGA3,IGF1R,CYR61,MEGF8,TRIM21,NTN1,EPB41L5,SUN2,ADAM17,RHOA,RAPGEF2,PIK3R1,ANO6,FURIN,KIF20B,EPHA1,ILK,BCAR1,EGFR,STX3,GPLD1,ONECUT1,SWAP70,INSR,SCG2,SEMA4D,PLPP3,CSF1,FGF18,ITGAV,GPER1,CFAP20,SEMA3A,DRD1 |
| 2.040e-05 | -10.80 | V$CEBP_Q2_01 | MSigDB lists | V$CEBP_Q2_01 | 259 | 63 | 17758 | 2588 |
PLA2G4A,NCKAP5,SPRED1,TM2D2,DYRK3,CDKN1C,HOXB7,THRA,ETV5,TESK2,MPP5,FAM91A1,DENND2D,ANO1,SLC25A35,SIRPA,NRP2,NEO1,CALR,WEE1,PTEN,CYR61,CALD1,LMO4,LHX6,MITF,PRKG1,FBXL14,BCL6,GYS1,TMBIM6,PDE4D,PLCB2,MAP3K3,ADAMTS2,CASK,CITED4,MOSPD2,LONRF3,WNT10B,PLS1,SPTLC2,PCTP,SNX12,EGFR,RHOB,EBF2,NFIX,XKRX,PITX2,LEMD2,KLF12,PRDX3,RIN3,PPP1CB,KLF5,NFKBIZ,SPRY4,ARF6,CEP41,TOB1,CBX4,XDH |
| 2.080e-05 | -10.78 | MODULE_321 | MSigDB lists | MODULE_321 | 109 | 33 | 17758 | 2588 |
LTBP1,GCLM,DYRK3,DEPDC1,COL18A1,GSTP1,PHLDA1,NRP2,CAPN2,APLP2,BTG3,ITGA3,CTSC,TAX1BP3,ALDH7A1,LRP11,PTPRE,CKAP4,SOAT1,SEC23A,CTNNAL1,ACO1,CASP4,FAS,TWSG1,CORO1C,FAM3C,CLIP4,NRG1,PDXK,ITGAV,NRGN,CBX4 |
| 2.087e-05 | -10.78 | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP | 197 | 51 | 17758 | 2588 |
SUN1,AGRN,ADD1,IL15,CAMKK1,HLA-E,HDAC11,TAP1,DGKA,SELL,FAM198B,SEPT4,TSPAN17,BEX2,FZD6,CDKN2C,PDGFA,ADD3,RALGPS2,NPNT,RDH14,TPST1,CRY2,NTN4,MYLIP,KANK3,EPHX1,POU6F1,SUN2,PRODH,ADCK3,TEF,PCBP3,STAT4,MRPS35,ATP8B3,STK17B,GIGYF1,GABARAPL1,MAGED2,TWSG1,NR1D2,SH2D3C,DGAT2,MAOA,WBSCR27,PER3,SERPINB1,ABCA1,DCBLD1,MAPK12 |
| 2.111e-05 | -10.77 | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN | 192 | 50 | 17758 | 2588 |
OTUD5,SCN5A,TTC39B,ARMC7,SUDS3,ARFGEF1,CUL1,VASH1,PJA2,SPSB1,CYP26A1,APPBP2,HDAC9,M6PR,CA2,CTSC,RGS3,PAK2,SLC30A6,RAB20,MTMR11,ALPK1,PIKFYVE,WBP4,IL1RAP,RASGRP1,TBC1D10B,CTH,GFPT1,ORAI2,SSH3,LAP3,ACBD3,BCL9,EZR,NFIX,TAPBP,TRAM2,SWAP70,CASP7,RBL1,FAM114A1,ITPR1,SIPA1L1,SLC4A3,SH3BP4,ZDBF2,KIF12,SLC25A38,CBX4 |
| 2.111e-05 | -10.77 | GSE3982_DC_VS_NKCELL_UP | MSigDB lists | GSE3982_DC_VS_NKCELL_UP | 192 | 50 | 17758 | 2588 |
LAMP1,NFKBIE,LGALS3,NQO1,RAB23,NDRG2,IL13RA1,MRAS,FTH1,CTSZ,NANS,PPP2R3A,ARHGEF10L,MAGOHB,SNX13,MITF,DRAM1,CD9,SGK1,RAB20,TACSTD2,CTTN,GM2A,CCDC88A,TUBA4A,PDGFC,TNIP1,CTNNAL1,FHL2,AK4,DIAPH2,TNS1,ASB13,CD83,CTNS,RBM47,PRDX3,H1F0,NGFRAP1,CSF1,P4HA2,PPM1H,NR4A3,RAB31,DTX4,MAOA,MDH1,CENPE,SLC31A2,CPPED1 |
| 2.111e-05 | -10.77 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | 192 | 50 | 17758 | 2588 |
CCNI,CMAS,CDS2,ARMCX3,PPM1J,SEC61G,CAST,NDRG1,MCTP2,FLOT1,FTH1,NUCB2,DDR1,SDF4,RND1,PDGFA,PHF7,ITGA3,TIMP1,TSPAN6,TOX2,MANF,PDIA6,ITM2C,CDKN2D,ALDH3A2,MED30,S100A6,SUSD3,CPD,SYPL1,TNIP1,TMEM43,BNIP3L,PRRC1,CYFIP2,FNDC3A,ALCAM,RANBP9,FRMD4B,AMZ2,CARHSP1,TWSG1,C1orf21,APPL2,ARAP1,RAB11FIP1,NFKBIZ,GEM,GOLGB1 |
| 2.130e-05 | -10.76 | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | 162 | 44 | 17758 | 2588 |
MYL9,GLIS3,CTHRC1,CCDC109B,SERPINE2,LGALS3,SLC16A14,SERPINB9,HAL,KCTD12,SLC7A2,DUSP5,BMP2,CXCL16,SRPX,CDH1,TIMP1,CAPG,TPST1,GOT1,ACSL4,CNGA1,RAB27B,MOXD1,LOXL1,SLC12A2,RASGRP1,TIMP2,MMD,SEPT6,STAT4,FURIN,CDA,GALNT7,EPHA1,CYFIP2,MYOM1,SOCS3,ETS2,FGFR2,RCAN2,MAL2,GEM,MAP3K5 |
| 2.130e-05 | -10.76 | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | 187 | 49 | 17758 | 2588 |
PARP12,PARP14,GMPR,HERC5,FBXO6,SNN,HERC6,HMGXB4,CAPN2,DTX3L,RCN1,SIPA1L2,TNS3,FAM46A,SP100,PIK3AP1,IFIT1,CTTN,OAS3,CKAP4,LAMP3,PARP9,REC8,MX1,VPS11,PLSCR1,LAP3,USP18,UTRN,BLVRA,IFIT3,TXNDC11,ZDHHC3,ULK2,C18orf8,MAN2A2,SCARB2,HPSE,C19orf66,TRIM69,RIN3,MYLK,STAT1,NOD2,PKD2,IRF7,KLF11,SAT2,IFI6 |
| 2.130e-05 | -10.76 | GSE30083_SP1_VS_SP3_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP3_THYMOCYTE_DN | 187 | 49 | 17758 | 2588 |
KLF2,COL9A3,CMAS,SCN5A,TBC1D1,LFNG,IQGAP1,ELOVL7,DGKA,FAM78A,ITPR2,CDIPT,HERC6,FAM101B,E2F7,CEP97,ADD3,KLF3,IL17RA,SGK1,ABCD1,OSTF1,IFIT1,ALS2CL,GM2A,SMC4,PHF20L1,CXXC5,PQLC3,USP18,DUSP23,C3orf52,SYNE2,EMP3,TNFAIP8L1,ESYT1,RAB3IP,NDRG3,RASGRP2,TNS4,LDLRAP1,PPP2R5A,APPL2,IRF7,PIEZO1,ARSB,TRAF5,F2RL1,IFIH1 |
| 2.130e-05 | -10.76 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | 187 | 49 | 17758 | 2588 |
ZMAT1,HECA,UPF3B,TRIM24,CPEB4,LGALS3,CAST,CD274,RAB6A,TRIB2,ETS1,DUSP5,TTYH3,SYTL2,KIAA1147,IL17RB,SLC25A45,TMEM87B,RALGPS2,ZCCHC12,AIM1,TNPO2,ARMCX6,DLG3,CITED2,CASD1,SLC35A1,RASGRP1,HP1BP3,DUSP1,NEK4,ALDH2,NR4A1,BCL9,RAPGEF2,PTGER4,SCRIB,GALNT7,ZBTB7B,TSC1,SWAP70,DOLPP1,RAP2C,INPP4B,PLXND1,RGS14,CD81,TOB1,JARID2 |
| 2.130e-05 | -10.76 | GSE3982_DC_VS_TH2_UP | MSigDB lists | GSE3982_DC_VS_TH2_UP | 187 | 49 | 17758 | 2588 |
PLEKHG3,MRC2,SORT1,NFKBIE,NQO1,DAP,ABCG2,FTH1,MRAS,CTSZ,FAM198B,PLXNA1,MAP1LC3B,PDXDC1,PHF1,PARM1,EPCAM,SNX13,PLCG2,MITF,CST3,ADCK2,TACSTD2,ACOX2,FAR2,TMBIM1,COQ10B,LITAF,DIAPH2,PYGL,TNS1,ALCAM,SESN1,ULK2,CD83,FUCA1,SERPINA1,FA2H,SLC9A6,SETD3,DTX4,TLE1,PITPNA,PLXND1,FZD5,RGS14,SLC31A2,CD33,PCSK5 |
| 2.143e-05 | -10.75 | GSE3982_NEUTROPHIL_VS_BASOPHIL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_BASOPHIL_UP | 182 | 48 | 17758 | 2588 |
DDX58,ANXA3,KLF2,PACSIN2,PLEKHJ1,DNAJC3,RET,NDRG2,FTH1,SLC20A1,PHLDA1,PRRG4,SCML1,MLPH,CTGF,MCF2L,BCL6,GLB1L2,ALPK1,SEMA3G,MYO5A,DNAI1,XKR8,RHOA,LONRF3,NRBF2,LPGAT1,CDA,BCL10,MSL1,AGPAT2,SLC4A4,PVRL2,SH2D3C,P4HA2,SIPA1L1,SECTM1,PPP1CB,CLMN,CANT1,ADIPOR1,SPRY4,TMEM8B,STARD13,PTGES,CPPED1,GOLGB1,EHD1 |
| 2.150e-05 | -10.75 | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | 177 | 47 | 17758 | 2588 |
GCLM,DYRK3,TXN,TMEM217,GNPDA1,ADO,XIAP,EGR3,SNX9,PHLDA1,DUSP5,ZFYVE16,SPP1,EFR3A,SGK1,RAB20,SELK,EGLN3,PTPRE,SPRY2,OSGIN1,WBP5,DUSP1,CKS2,TGIF1,MFI2,LONRF3,NR3C1,NR4A1,COQ10B,PLAUR,KBTBD8,DUSP4,STX3,RHEB,IL1R1,SLCO4A1,PTGS2,PRKAG2,ETS2,CSF1,NR4A2,GLA,GEM,ZC3HC1,ESYT2,RRAGD |
| 2.153e-05 | -10.75 | tubulin binding | molecular function | GO:0015631 | 265 | 65 | 16491 | 2452 |
GAS2L1,KIF3C,NDRG1,KIF2C,HDAC6,KIF26A,APC2,MAP1LC3B,STIM1,DPYSL2,KIF14,REEP1,DNM2,KIF22,DIXDC1,CHP1,PLK1,CAMSAP3,PSRC1,KIFC2,CAPN6,UXT,KIF1C,EZR,KIF13A,NUSAP1,DAG1,GABARAPL1,FYN,MAP2,TRAF3IP1,FAM110C,RGS14,REEP4,PIFO,ARL4C,KIF23,RACGAP1,KIF5B,KIF13B,CENPJ,TUBGCP6,TBCD,KLC3,PRC1,CLIP2,CCDC88A,DPYSL5,SUN2,KIF20A,FMN1,B9D2,SYBU,STMN3,KIF20B,KIF11,SKA1,MAP1B,FNTA,HTT,AGBL5,FAM83D,CENPE,NDE1,KIF12 |
| 2.178e-05 | -10.73 | regulation of cellular process | biological process | GO:0050794 | 10106 | 1600 | 16441 | 2455 |
HECA,IBTK,GRIK2,PNPLA2,HEXB,RET,BAIAP3,SNX9,SPSB1,CARD10,LTBP3,GRM5,ZNF275,NPM2,CDKN2C,DNM2,CLDN4,CRY2,PPP1CA,TMEM37,TIAM1,IL10RB,TIPARP,CPE,ANKRD9,NEK4,DSTN,UXT,CDA,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,LCP1,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,HSPB1,STARD13,ZNF720,SCN5A,SEC61G,ITGA6,RAB23,GPSM2,FAM21C,HPCAL4,TFAP4,FLII,RAC2,PAIP2B,MEGF8,RIMS3,FLRT3,FBXO7,RANBP1,MAP3K9,SLAIN2,USP38,USP1,MYDGF,CNGA1,MAPK7,DGKG,MYLIP,NUP85,PHKG2,PPP6R1,PAQR7,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,PSMA4,GNA11,PLIN5,IL1R1,FNTA,ETS2,CLMN,OSCP1,STK39,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,ADAMTS16,DOCK9,DMPK,NQO1,LFNG,INPP5D,CD82,PTTG1,MAPK4,GRK6,MVB12B,ST5,CDH1,SH3BP1,TAX1BP3,DLG3,RASGEF1A,MYT1,ETV4,MX1,SEC61B,RIPK2,APOBEC3D,PFKFB2,SAT1,VPS4B,HTATIP2,SYP,GTF2A2,SNX12,ZNF618,EBF2,GIGYF1,NFIX,CCNB3,CDK19,SHROOM3,CORO1C,WFS1,AXL,MAPK12,CTHRC1,TCAF1,HSP90B1,MPZL1,CKAP2,TRAF2,ESRP1,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,PLPPR4,ZNF219,HDGFRP2,IFT27,NFAT5,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,PDCD10,ITGB8,IGSF9,KNDC1,GPC3,FAM20B,CST3,TUBGCP6,BAX,IGFBP2,RAG1,MED22,PLSCR1,TACC1,PIK3R1,NUB1,UBE2A,PGBD1,PIM3,CNTNAP1,LDLRAP1,PROM1,SYT7,DBI,NR4A3,SSNA1,ITGAV,OSR1,CD81,SRSF9,CCNI,ILDR1,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,SPTB,FANCI,TFAP2E,SUSD2,BTG3,RPS6KA2,NUP210,CTNNB1,NPNT,P4HB,IL6ST,ARL1,PSMC2,MITF,PASK,ABCA2,SCARA3,PLK1,THRB,KCNIP3,MARK1,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,EAF2,SESN1,KDM4D,TRIM9,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,KPNA2,TC2N,MYL12B,RRAGD,RUNX2,LMTK3,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,PSMD7,SORBS3,RAB6A,HES2,NCKAP1,FBLN1,ANO1,TNS3,TIMP1,KIF13B,TBCD,SLC30A6,SELK,PIM1,NTN1,WNT3A,DPYSL5,USP31,RGMB,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,NMT2,CDK5R1,FOXD2,RASGRP2,FA2H,PHLPP2,NLRC5,FAM213A,PLD1,SEMA3A,CDAN1,CCNB2,USP43,RAD21,HOXB7,CTDSPL,TMX4,TP53,P2RX7,RHPN2,BAHD1,STIL,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,KMT5C,TACC2,LMO4,PPME1,BCL6,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,C3orf33,DAG1,PTGS2,ZNF628,PTPRJ,IDE,RBL1,STK38,CHMP4B,XRCC3,EFNA5,IRF7,SYT13,ARHGAP4,FAM134B,ARFGEF3,CTDSP1,BIN1,ZMAT1,PINK1,CPEB4,TAB3,CTSB,GNAL,MCTP2,CDCA8,ERCC6L,GTF3A,GDF15,HMGN3,AIP,IL22RA1,PARM1,DNAJB9,FZD6,SH2D4A,NRP2,M6PR,CD109,FOXP2,CDK16,GTF2F2,UBE2J1,TFAP2A,SGK1,IL17RA,TRIM21,CPLX1,TSPAN13,SYK,FAM134C,DUSP1,WBP5,NFE2L3,P2RX4,HES1,FBLN5,RHOA,HMGN5,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,COL7A1,BBS2,TXNDC11,DGKE,BCL10,USP6,CNOT2,DDAH1,SCG2,FGF18,E2F1,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,TSC22D3,CUL1,PSME1,PDGFRL,CAMK1D,SEPT4,VASH1,PJA2,PICK1,PAK6,HELZ2,CYP1A1,ZNF823,STIM1,FOSB,KCNS3,PIK3CA,IRF2,TACSTD2,ZBTB18,METAP2,ACVR1C,CDYL,BNIP3L,SLC35C1,LDB2,POR,RAB2B,ANKRD10,SH2D3C,PPP2R4,PRDM5,MAPK13,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,FGD1,SEMA6B,CDKN1C,SCOC,DHPS,TBC1D1,THEMIS2,PRKAA1,AKAP17A,TXNDC9,TNFRSF19,TSPAN7,PSIP1,SH3RF2,MESDC2,CALR,C9orf69,RALGPS2,BHLHE41,VASN,PPP4R1,MSH2,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,DLX4,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,GCC2,KLK5,CALM1,DCHS1,WHSC1,NPC2,EPHA1,ANTXR1,NFIB,PDE11A,AP1AR,PLEKHH2,TJP3,PELI2,PIAS2,FAM83D,MPP2,ARAP1,APPL2,SFMBT1,CABIN1,SAMD8,CDK18,ZBTB34,PER3,IFIH1,EHD1,SPRED1,FOXO6,TCF25,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,NDRG1,FTH1,BCL2L1,FLT3,DDR1,ZFYVE9,EPS8L2,EPM2A,APOBEC3B,CD46,NOV,CCNA2,RALB,PDE4D,EPHB4,OSBPL7,TSPAN1,FLOT2,MED30,SEMA3B,DOCK4,FOXJ2,DRAP1,UTRN,CLSTN1,ATP1B1,RAD17,PYGO1,PKMYT1,CBL,ASB13,ITPR3,ALCAM,FZD7,NGFRAP1,TSPAN18,TRIOBP,AREL1,CBX7,COBL,PRKAR1A,DEPDC1,IGFBP6,CENPI,EPS8,NES,CBLL1,PBX3,HERC5,PLD2,SPDL1,EFNB1,FGF19,ADGRB2,HLA-A,WWP2,SCML1,CKAP5,RASSF8,E2F7,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,TTPA,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,TCFL5,ZKSCAN2,FBXO9,DIAPH2,YES1,FOS,KIF11,CRTC2,CDK5RAP1,TIMP3,FGFR2,RIN3,TBX18,RYK,RABL6,LRRK1,FZD5,ESPL1,MELK,RGMA,CCNC,CRYM,VARS2,COMMD5,MAP1LC3B,ERP29,SLC8B1,TRIM68,HTR1D,ZFYVE16,EPCAM,SIPA1L2,RAB15,HSF2,CDKL5,ARHGEF37,SIVA1,TRPC1,ASH2L,CTTN,MYRIP,IL1RAP,SP5,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,USP18,ARHGDIB,TYSND1,GPRC5B,HPSE,MADD,CAB39,ZNF165,SP6,GLA,CHPT1,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,ZNF395,PPP1R12A,BVES,ETV5,ASB9,CALM3,TEC,ADAMTSL4,DUSP5,QSOX2,SPP1,NOXA1,FAM20C,PFKL,OCRL,SUCO,PRKCI,BRAT1,NPTN,HLA-C,C10orf54,ZRANB1,ETV7,CCDC88A,MDFI,ELK3,PDE5A,KIAA1109,NUBP1,C3orf58,RANBP9,RHPN1,SOX13,INSR,TMEM30A,SH3BP4,RAB31,DCUN1D1,NXPH4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,RARG,DRD1,LMO7,CCNE2,LZTFL1,SORBS1,PAX6,HDAC11,SOD2,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,EXT2,MXD1,SAP130,ZNF687,ARTN,KIF14,REEP1,FABP6,ZBTB49,DIXDC1,ECE1,EPB41L4B,NFKB2,UPF3A,EBAG9,CHP1,CKS2,SOAT1,PTPRU,GLO1,CD40,CDC25C,CASP4,PDHX,ARHGAP35,SOCS3,HSF4,JADE1,STAT6,SECTM1,TLE1,PTBP3,SPTBN5,RCAN2,MAD2L1BP,ABCA1,GLIS3,FBLIM1,GCLM,TSPAN15,ARHGEF11,SH3D19,CIT,ARHGEF7,SERPINB9,TGFBR1,TRIB2,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,ZDHHC13,H2AFY,KANK2,MYO5A,DCAF6,WNT10B,SYBU,RC3H2,RGCC,RUNX3,NDRG3,TCEAL8,FOXL1,LEPR,LEMD2,ARHGAP24,CTSL,CD8A,CASP7,SWAP70,RND3,CTSV,SPINT2,RAP2C,DTX4,UACA,ARRB1,ZMIZ1,AHR,CD33,ABCG1,NGEF,DOC2A,ACACB,TRIM24,ADD1,IL15RA,TRIM5,DNAJC3,SMARCAL1,FBXO2,XIAP,CACNA2D2,NRG2,LGI3,IL18,MORF4L2,SYTL4,CA8,KIF26A,BARD1,PHF1,TP73,CALM2,DAPK2,WEE1,ZYX,ARHGAP42,PSMD1,TGFBR3,RGS12,CABP1,ALDH1A3,KLF3,SEMA3G,PIK3CD,APOBEC3G,VPS11,SMARCA2,TNIP1,SH3BGRL,SPRTN,LOXL2,F12,ICMT,PPP1R14C,PGF,CAMK2N2,GRID2IP,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,SERPINB6,ARF6,LSM14B,E2F8,PDPR,GAB1,HOXC13,NFKBIE,NUAK1,SOX9,ZNRF3,MERTK,LMNA,ELF3,WDFY1,FAM13B,NEK2,NCAM1,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,ILK,TP53INP2,RHOB,STK17A,PTPRF,NCOA3,SEMA4D,HTT,SETD3,ITPR1,OSMR,AURKA,NDE1,ARPC2,TRPC3,ZNF502,SERPINB1,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,ACTR8,RGS20,WDTC1,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,RNF169,SSH3,CAMSAP3,PSRC1,LGALS8,NRBF2,FZD4,SYNE2,NUSAP1,CDCA2,PXYLP1,RAB38,IRS2,PEX5,SLC9A6,WWTR1,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,RGS14,GEN1,ARNT,FARP1,TNRC6C,TAOK2,NKX3-1,RBM24,PARP14,RASSF7,PDIA3,GMCL1,ANO9,PKN1,KCNC4,ETS1,GSTP1,ARHGEF40,TSPAN17,HOXB2,TIPRL,SRPX2,ICAM1,NEO1,PDIA4,CAPN2,CXCL16,ANK1,IRAK1,CTSC,KCNK5,MCF2L,PLEKHF1,ADAM15,TMBIM6,WWP1,ZNF230,MAPK11,ITM2C,TPCN1,S100A6,TMX1,CRTAP,HCN3,AMOTL2,POU6F1,FMN1,CTNNAL1,BCL9,RAPGEF2,EIF5A2,GRIN1,EMP3,NEURL1B,SKA1,ABLIM2,TXK,PITX2,BTG1,KIAA0141,ACVRL1,NR1D2,ATXN7L3,ZFP30,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,FOXA1,MYL9,SIGIRR,UNC93B1,TRIM2,AGRN,CUL4B,EPHA4,SUDS3,NDC80,TP53I11,HDAC6,PDGFB,SDC1,PCNA,SHC3,DDHD2,ELF5,DUSP10,TNFRSF18,RGS5,MYBL1,S100A13,NEB,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,C12orf65,EZR,TNFAIP8L1,ERP44,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CLCN2,CDK1,VCP,PLEKHB1,RHEB,OPTN,DPYSL3,IRX3,PLCH1,TBC1D17,WIPI1,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,POMT1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,RACGAP1,DOCK11,DHRS3,IL18R1,SSX2IP,CORO1B,BMP2,RB1,DAZAP1,VASP,IGF1R,GATA2,PAK2,MDFIC,PLCB2,PSMA5,CYP26B1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,PVRL2,ITGA7,CSF1,LTBP2,ATP1B3,CTBP1,IFI6,RNF146,KCNAB3,AVPI1,NF2,UPF3B,FOXM1,P3H2,DGKA,ZNF28,ERBB2,CCDC68,RASGRP3,CCNL1,SLC7A2,LPIN3,CYP26A1,PER2,CDK14,RAD23A,ATP6V0B,SRPX,PLCG2,LHX6,SCN2A,EGLN3,DVL2,CTH,SIRT1,TIMP2,TCEB2,FIGNL1,S100A4,CDC20,MYL12A,MYPOP,DNAJC10,DUOX1,ATP1A1,PTK7,PSMD3,ZBTB6,AIFM3,CNEP1R1,ZNF701,ZC3HC1,PACSIN2,MACC1,CD63,ADGRG1,DAP,GABRG2,PSMD10,SELL,NKRF,JAG2,CRABP2,PPP2R3A,GBX2,SLC35B4,BUB1,KLF9,HEXIM2,FAIM,CAMK2G,TLE6,PSMB4,NR3C1,IFITM3,AMFR,LITAF,PPARA,CAPNS1,CARD19,TRIM35,FXR2,PELI3,AKAP3,BORA,BCAR1,MAPK8IP1,PRDX4,CD83,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,NMI,NETO2,PPP2R3C,PKD2,SPCS3,NDFIP1,TBC1D4,UBE2C,ACVR1,PPP4R4,FAM129B,ATP8A1,KLC2,TAP1,GATA3,PLXNA1,CCNB1,PLA2G16,SLC20A1,FAM101B,RIC1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IL31RA,ATRNL1,PACSIN1,TFG,RCAN3,PBK,CASP9,NBPF3,AGO4,PIF1,AURKB,CCNF,SAV1,SLC25A5,ZFAND5,ARHGEF26,ULK2,SGPP1,AHRR,HLF,SLC25A4,AREG,PLK2,TBX1,NKD1,FAM110C,EIF4EBP2,TMEM8B,UNC5B,TRAF5,LZTS1,DLAT,DDX58,KLF2,INPPL1,CDK17,HLA-E,DGKQ,SLC25A27,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,ITGA3,CYR61,PIK3AP1,NECAB3,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,TSPAN33,RIMS2,EEF1D,EPB41L5,QSOX1,ZNF84,MMD,MFI2,B9D2,MICB,AMER1,ANO6,PIP4K2C,KCTD20,CYFIP2,KDM3A,FBXO10,RASA1,STX3,FAS,DGKH,GABRD,SERTAD2,PRKAG2,CSNK1G1,NAB2,TCEAL4,FGD6,NR4A2,EFNA1,MAP3K5,IRF1,PLA2G4A,PLEKHG3,ELK4,ARMCX3,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,SUZ12,CAST,IRX4,CD274,EGR3,AIFM2,MNS1,GNB2,APLP2,ZNF75D,DOK4,TNPO2,CDKN1B,DAB2IP,IFIT1,LGMN,NR2C1,TMBIM1,TBC1D10B,CDKN2AIP,CAPN6,DMTN,COX11,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,EPHA10,ZNF641,FYN,PPP2R5A,JAK1,STK26,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,NR3C2,ATMIN,WASF3,ARHGEF3,PCOLCE,ARL4C,GPR180,APOBEC3H,LGALS3BP,TEAD3,SIX4,RND1,SNTA1,FAM111A,OXCT1,PTEN,CENPJ,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,MAP3K7,CNOT6L,GFI1,CNPY3,TRIM62,SPRY2,OSGIN1,NCOA2,RASGRF1,ARAP2,CASK,MPP1,TEF,VAMP3,FURIN,GPLD1,NUCB1,RGS9,PRDX3,SERPINB5,GRIN2D,GPER1,ARSB,CPEB2,USP16,JARID2,EXPH5,EMX1,LTBP1,CASP3,ST13,CAMKK1,KIF2C,TAF6L,CACNB4,DNER,KREMEN1,SH3KBP1,PTCHD4,ARHGEF10L,GRHL1,ZCCHC12,TSPAN6,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,RAB20,MYH14,ARNT2,SLC39A10,PTPRE,RASGRP1,SOD1,TRIM8,SYNE3,ASCL5,STRIP2,RNF165,ROR1,STK17B,ADRBK2,EDNRA,SEC14L2,CXXC4,MDK,NEIL1,ARHGEF19,ZNF114,IARS2,ADIPOR1,RAP1GAP,PSMC1,MIIP,PPP2R5D,GRN,PIFO,LRRFIP2,ATP6V1E2,PHLPP1,ZNF432,CA2,LRRN2,KCNN4,DIAPH2-AS1,EBF4,FNIP1,FXYD5,ZNF692,KNTC1,RFX5,ACAD8,LRIF1,ALS2CL,HP1BP3,OXR1,HMG20B,FBXO8,EGFR,FECH,GNAS,BCAR3,NUDT16,ONECUT1,TSC1,PLPP3,CGREF1,NFKBIA,CDCA5,RHOBTB2,EGFL7,YOD1,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,SLC2A8,PSME2,PATL2,MICALL2,ARHGEF16,SS18,SVBP,SETDB2,FRYL,SMO,TWIST1,STEAP3,GOT1,APIP,PDIA6,F2R,HSPA2,FRS3,MAP3K3,ZNF525,TAF5,BAG4,KREMEN2,ERBB2IP,DUSP4,SNAPC2,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CANT1,PLXND1,AKNA,SGOL1,LIFR,PPP2R2D,CBX4,ANXA3,SORT1,FRMD6,LRP4,MIER3,AES,NOTUM,ZNF212,IRF2BPL,IL17RB,SNX13,ADORA1,KIAA0319,CKS1B,BRD7,MXD3,IQGAP3,SUN2,ADAM17,RAB3B,CENPC,ASPM,NR4A1,DEPDC4,GCLC,MBNL3,MPV17L2,MAP1B,HLA-B,DHRS2,PRCP,UBE2D2,TADA2B,HOXB13,GEM,ATP6V1C1,SOX8,L1CAM,ZNF596 |
| 2.213e-05 | -10.72 | WGGAATGY_V$TEF1_Q6 | MSigDB lists | WGGAATGY_V$TEF1_Q6 | 351 | 80 | 17758 | 2588 |
SPRED1,BCAM,AVPI1,GALNT12,ERBB2,NRG2,SEPT4,DDR1,PCBP1,SPTB,SYTL2,APPBP2,PLS3,ADPRHL1,PDGFA,CDKN2C,SCNN1A,ST5,CTGF,SH3BP1,RGS3,DACT1,IL6ST,CDH3,TINAGL1,NFKB2,DLG3,ZNF462,SMARCA2,ASXL1,KIF1C,KLK6,ITPR3,MYL12A,MDK,PGF,PIAS3,PTPRJ,RBM47,WIPI1,PRKCDBP,NRG1,SLC31A2,LIFR,HOXC13,IGFBP6,MAN1A2,NES,COL4A5,NOTCH2,SRPX2,TSPAN17,SIX4,PRRG4,LMNA,ELF3,FOXP2,ITGA3,CYR61,PRKCI,CKS1B,TSPAN33,TGIF1,NR4A1,DENND1B,LRRC1,PRX,DDX23,RASGRP2,ARHGAP24,FGFR2,C1orf21,NR4A3,SH3BGRL2,HMGA1,HOOK1,RARG,EHD1,DMPK,DIS3L |
| 2.229e-05 | -10.71 | MODULE_239 | MSigDB lists | MODULE_239 | 114 | 34 | 17758 | 2588 |
TRIM24,TBC1D1,DNAJC3,RAB6A,BCAP31,CHPF,PDIA4,APLP2,IL6ST,DLG1,PCYOX1,MANF,LRP11,TMED2,CCDC88A,SYPL1,FADS2,B3GNT2,TACC1,LPGAT1,ACBD3,PIK3R1,GLO1,PRRC1,GIGYF1,IDE,PPP2R5A,TWSG1,CAB39,ADIPOR1,PLXND1,C1orf43,RTN3,OCLN |
| 2.234e-05 | -10.71 | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | MSigDB lists | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | 133 | 38 | 17758 | 2588 |
LTBP1,ACVR1,NKX3-1,HOXB7,VANGL1,ADO,BIK,PBX3,RASGRP3,COL4A5,SEPP1,HOXB2,LMNA,CORO1B,SGPL1,GATA2,KCNK5,RRBP1,DRAM1,IGFBP2,SNX10,SCYL3,TMBIM1,SMC4,WBP5,NFE2L3,ADAM17,PLS1,RAB38,FZD7,BCL10,DPYSL3,NGFRAP1,HOXA9,LRIG1,NAB2,CTNND1,WDR91 |
| 2.251e-05 | -10.70 | LGALS9 (lectin, galactoside-binding, soluble, 9) | protein interactions | 3965 | 72 | 26 | 16036 | 2547 |
ENPP4,CLCN3,MRC2,LGALS3,MPZL1,CD63,OSTM1,PBK,PDIA3,PLXNA1,PTGFRN,ALCAM,FBLN1,DAG1,SLC9A3R2,CD109,SLC6A6,PTPRJ,CTNNB1,P4HB,SLC9A6,ATP13A3,SORL1,PDIA6,SLC12A2,IGSF3 |
| 2.283e-05 | -10.69 | ameboidal-type cell migration | biological process | GO:0001667 | 154 | 43 | 16441 | 2455 |
SEMA6B,ACVR1,RET,TGFBR1,EGR3,NCKAP1,PKN1,S100A2,EMP2,EFNB1,FGF19,GBX2,CORO1B,SGPL1,NOV,PTEN,MEGF8,SMO,PIK3CA,TWIST1,SEMA3G,EPHB4,CYP1B1,SEMA3B,EPB41L5,NR4A1,SYNE2,TNS1,LOXL2,ILK,ANLN,ZFAND5,GPLD1,PITX2,SEMA4D,SCG2,CORO1C,TBX1,STAT1,PLXND1,SOX8,ARSB,SEMA3A |
| 2.309e-05 | -10.68 | GOZGIT_ESR1_TARGETS_UP | MSigDB lists | GOZGIT_ESR1_TARGETS_UP | 138 | 39 | 17758 | 2588 |
ACACB,UGT8,DEPDC1,KCTD12,IL18,B4GALT4,ADAMTSL4,BMP2K,CYP26A1,FRY,GRHL1,ALPP,GATA2,TFAP2A,LIMCH1,CACNA1D,PIM1,C10orf54,SLC39A10,NAGA,SLC16A5,SGCE,SEPT6,FHL2,PTGER4,PRKAR2B,FOS,COL12A1,CRISPLD2,ALDH3B1,FYN,PRKAG2,DHRS2,GRAMD1C,PLD1,FHL1,PROM2,ABCG1,XDH |
| 2.311e-05 | -10.68 | TGGAAA_V$NFAT_Q4_01 | MSigDB lists | TGGAAA_V$NFAT_Q4_01 | 1781 | 319 | 17758 | 2588 |
PPP4R4,HSPG2,VANGL1,TSC22D3,SLC25A13,MCOLN3,GATA3,SYTL4,MORF4L2,BAIAP3,SEPT4,CMTM6,SLC9A7,TYMP,NAPG,ANKS6,CTGF,RGS3,PAQR5,STEAP2,ATRNL1,MANF,TINAGL1,TMEM37,ARMCX6,WBP4,CPE,TIAM1,SMARCA2,VPS11,SERTAD4,DSTN,TNS1,GALNT7,LDB2,ZFAND5,PNKD,COL12A1,ABR,SLC44A3,ENPP1,SLC25A4,AREG,SERPINI1,STARD13,CDK17,MRC2,SOX9,ISYNA1,GPSM2,APBA1,TNFRSF19,PSIP1,BMP2K,MECOM,TFAP4,CYR61,SLC16A6,FLRT3,ATP5H,ZIC5,FBXL14,DGKG,C9orf72,IGSF3,TBC1D8B,CALCRL,WHSC1,CYFIP2,ANTXR1,NFIB,RHOB,NCOA3,NT5C2,PRKAG2,ETS2,SEMA4D,PELI2,NAB2,ITPR1,C1orf21,SLC4A3,SFMBT1,NR4A2,MDH1,ZNF502,RPS6KA3,DOCK9,SPRED1,CEP70,GPR107,CAST,CD82,DDIT4L,RNF182,MAPK4,FTH1,BLCAP,PRKACA,APLP2,SCNN1A,RNF220,FAM46A,XYLT2,PDE4D,RASGEF1A,SCN3A,DOCK4,CAPN6,LYRM1,SYNE2,RAB38,ATP1B1,SNX12,EBF2,FZD7,NIN,NFIX,IRS2,PDLIM3,NGFRAP1,CORO1C,NRG1,KLF5,HS3ST3B1,SLC27A3,NR3C2,OTUD5,CTHRC1,GCAT,MAN1A2,SDC4,FLOT1,ETS1,HOXB2,NFAT5,ICAM1,WWP2,ADD3,ITGB8,RNF128,PPP1R10,CALD1,TMEM62,TMBIM6,ERBB3,CITED2,GFI1,ITM2C,SPRY2,ADAMTS2,TGIF1,CASK,LCA5,BCL9,VAMP3,GRIN1,C1GALT1C1,RAB3IP,FOS,ABLIM2,PITX2,BTG1,CCDC6,PLOD2,NR4A3,SHOX2,DEF6,JARID2,ESYT2,CCNI,CCNC,EMX1,LTBP1,ILDR1,ST13,CNOT8,FHDC1,NDRG2,PLAC1,HDAC6,PDGFB,TMC1,TSEN34,SH3KBP1,NKAIN3,LRRC6,DPYSL2,IL6ST,PHTF1,MITF,ELF5,AKR1B1,TECR,BTBD3,TRIM8,HN1L,LAP3,ACBD3,EAF2,CLCN2,VCP,EDNRA,TMEM164,KLF12,HOXA9,KLF11,CTNND1,GLA,NRGN,PPP2R5D,MAFF,HS6ST3,PCSK5,ARAP3,CHCHD7,UBASH3B,ETV5,SORBS3,RACGAP1,RAB6A,CNTNAP2,FAM81A,ADAMTSL4,DHRS3,IL18R1,BMP2,SPP1,TBCD,MDFIC,PIM1,GAD1,CYP26B1,ELK3,MGAT4B,SPA17,VWA1,PDK3,GNAS,XKRX,BCAR3,H1F0,ITGA7,NFKBIA,DONSON,ATP1B3,LTBP2,SEMA3A,RARG,COL16A1,KLF7,NCKAP5,PAX6,HOXB7,TP53,DGKA,RASGRP3,BCAP31,C1orf116,IER3,RAD23A,PER2,SRPX,TACC2,WDR44,LMO4,BCL6,TWIST1,ESPN,NFKB2,SCN2A,LOXL1,CLCN3,ACO1,TMTC2,PTK7,OVOL1,ADAMTS14,RCAN2,SORT1,TM2D2,CPEB4,KLHL13,MIER3,HMGN3,NOTUM,TRIB2,IL22RA1,PPP2R3A,IL17RB,FOXP2,C16orf74,ADORA1,RRBP1,CKS1B,SGK1,ABCD1,IQGAP3,ATP2B1,RBMS2,CAMK2G,RHOA,MOSPD2,NR3C1,NR4A1,PPARA,FXR2,MAP1B,HLA-B,SMTNL2,SCG2,HNRNPH2,RAP2C,FAM117A,SH3BGRL2,ZMIZ1,CEP41,PTGES,DIS3L |
| 2.314e-05 | -10.67 | PHOSPHORYLATION | MSigDB lists | PHOSPHORYLATION | 308 | 72 | 17758 | 2588 |
TNK1,ACVR1,NF2,RET,ERBB2,TESK2,MAPK4,BARD1,PICK1,CCND1,DAPK2,CDKN2C,CDKL5,IL31RA,PLK4,CDKN1B,F2R,CDKN2D,MAP3K3,NEK4,MARK1,AKT1,RAD17,MAP3K6,STK17B,LIMK1,STK38,MYLK,KIAA1804,STAT1,MAP3K11,MAPK12,PRKAA2,PINK1,DYRK3,CDK17,PRKAA1,TGFBR1,TRIB2,PKN1,MERTK,IGF1R,CDK16,PAK2,SGK3,MAP3K9,DAPK1,PRKG1,PRKCI,SGK1,PIM1,ERBB3,CCDC88A,PIK3R1,STRADB,EIF2AK1,ILK,EGFR,BCL10,STK17A,TXK,PRDX4,MAPKAPK2,INSR,ACVRL1,NR4A3,AURKA,CD81,JAK3,HIPK3,CTBP1,DMPK |
| 2.324e-05 | -10.67 | Interleukin receptor SHC signaling | REACTOME pathways | R-HSA-912526 | 238 | 60 | 8202 | 1235 |
SPRED1,INPPL1,PSME2,IQGAP1,RASA2,INPP5D,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,DUSP5,FGF19,SPTB,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,RASGRP1,CAMK2G,PSMA5,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,DUSP4,PSMA4,EGFR,RASA1,IRS2,FYN,JAK1,PPP2R5A,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3,PPP2R5D,PSMC1 |
| 2.336e-05 | -10.66 | MAPK1 (mitogen-activated protein kinase 1) | protein interactions | 5594 | 284 | 72 | 16036 | 2547 |
IQGAP1,RPS6KA1,RET,TP53,HDAC6,BARD1,IER3,CCND1,RPS6KA2,MITF,BCL6,PPP1CA,PDE4D,EGLN3,PTPRE,NEB,METAP2,FRS3,MBP,TNIP1,SYNE2,CASP9,DUSP4,CDC25C,VCP,HSF4,ATP1A1,GNPTAB,SH2D3C,KLF11,LIFR,GAB1,ZC3HC1,MAPK12,SORBS3,ETS1,GSTP1,DUSP5,CAPN2,TOP2A,RB1,NOXA1,GATA2,PAK2,NEK2,DAPK1,ADAM15,CTSD,SPRY2,DUSP1,HMMR,TGIF1,ADAM17,NR3C1,NR4A1,PTPRH,PPARA,FHL2,ELK1,FOS,EGFR,PTPRF,MAPKAPK2,NCOA3,INSR,RYK,DCUN1D1,ARRB1,CENPE,NDE1,TOB1,RPS6KA3 |
| 2.340e-05 | -10.66 | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | 208 | 53 | 17758 | 2588 |
UNKL,MYL9,PCOLCE,ZNF395,DEPDC1,CALB2,PKP2,PDGFRL,MGAT5B,TRIB2,ZNF219,SDC1,LTBP3,SYTL2,PLS3,CDKN2C,SPP1,TNS3,SESN3,AP1M2,CALD1,DACT1,VASN,ATP8B1,RTKN2,NTN4,TMEM37,NPTXR,LRP11,SCARA3,LOXL1,MYBL1,SEMA3B,DUSP1,KRT80,ATL1,FADS2,S100A4,DSTN,TNS1,LRRC1,GLT8D2,NFIB,ENDOD1,ALDH3B1,TIMP3,WIPI1,MATN2,RIN3,MYLK,HDAC1,COL16A1,OCLN |
| 2.346e-05 | -10.66 | ACTTTAT,MIR-142-5P | MSigDB lists | ACTTTAT,MIR-142-5P | 276 | 66 | 17758 | 2588 |
SUN1,SORBS1,EPAS1,TRIP10,VANGL1,FAM129B,ABCG4,EGR3,FAM91A1,PCBP1,SPSB1,BTG3,ZFP36,CNNM4,SNX16,EGLN3,STK35,CLCN3,FOXJ2,RNF165,ATP1B1,TANC1,ALCAM,FZD7,NRG1,KLF11,ABCA1,FAM134B,TAOK2,CDK17,CPEB4,SCOC,BVES,FXYD3,SLC25A27,FAM134A,MIER3,PBX3,ARHGEF40,NFAT5,SIX4,BMP2,ZFX,CEP97,RNF128,BHLHE41,TRIM3,WWP1,ATP2B1,MSH6,CHSY3,RHOA,DCHS1,MGAT4B,UBE2A,FNDC3A,FOS,BTG1,SLC4A4,TMEM54,SYT7,NETO2,OSR1,AHR,CPEB2,RGMA |
| 2.368e-05 | -10.65 | ENZYME_REGULATOR_ACTIVITY | MSigDB lists | ENZYME_REGULATOR_ACTIVITY | 319 | 74 | 17758 | 2588 |
IQGAP1,DNAJC3,RALBP1,RGS20,XIAP,ARFGEF1,RASGRP3,ARHGEF10L,CDKN2C,RGS12,RGS3,CABP1,ARL1,PPME1,CDKN1B,TWIST1,RGS5,CDKN2D,TIAM1,DOCK4,TIMP2,CASP9,PRKAR2B,ARHGDIB,PRKRA,ABR,SOCS3,PPP2R5A,MMP17,PPP2R4,MADD,SERPINB6,SERPINI1,RGS14,ARHGAP4,RAP1GAP,AIFM3,PPP2R5D,FGD1,PRKAR1A,ARHGEF3,ARAP3,FARP1,CDKN1C,PPP1R2,ARHGEF11,RASA2,SERPINB9,RACGAP1,PPP2R3A,CARD8,TIMP1,CST3,RANBP1,HEXIM2,FARP2,RAPGEF2,PIK3R1,EGFR,CDK5R1,MAPK8IP1,RASA1,BCL10,MMP15,RGS9,RCBTB2,SPINT2,ARAP1,ARRB1,ARFGAP3,FGD6,CTSA,MAP3K5,PKIA |
| 2.380e-05 | -10.65 | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | 105 | 32 | 17758 | 2588 |
GLIS3,PLA2G4A,CPEB4,RBM24,LGR4,NDRG1,OSGIN2,ETNK1,DUSP5,ELF3,PCNA,DAPK1,ADCK2,ACOX2,NOTCH3,FAM84B,LRP11,SLC12A2,SULT2B1,ETV4,CTH,CYP1B1,CD55,SAT1,GABARAPL1,BTG1,ACYP1,SAMD8,ATP1B3,EFNA1,ANXA11,FOXA1 |
| 2.381e-05 | -10.65 | PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 203 | 52 | 17758 | 2588 |
ACVR1,TAOK2,PINK1,CIT,RPS6KA1,TESK2,TGFBR1,MAPK4,DAPK2,RPS6KA2,IRAK1,PAK2,SGK3,NEK2,MAP3K9,PLK4,PRKCI,SGK1,MAPK11,PIM1,MAP3K7,PHKA2,MAPK7,PHKG2,PLK1,NEK4,MAP3K3,MARK1,RIPK2,AKT1,ACVR1C,TESK1,PBK,EIF2AK1,XRCC6BP1,ILK,MAP3K6,STK17B,CDK1,STK17A,MAPKAPK2,ACVRL1,LIMK1,STK38,MYLK,MAP3K11,MAPK13,MAP3K5,HIPK3,RPS6KA3,MAPK12,DMPK |
| 2.398e-05 | -10.64 | CELL_SUBSTRATE_ADHESION | MSigDB lists | CELL_SUBSTRATE_ADHESION | 37 | 16 | 17758 | 2588 |
SGCE,TAOK2,SORBS1,FBLN5,NF2,TESK2,RASA1,TSC1,ITGA3,COL13A1,ACVRL1,PTEN,ITGA7,ADAM15,PKD2,TMEM8B |
| 2.399e-05 | -10.64 | cytoplasmic membrane-bounded vesicle | cellular component | GO:0016023 | 1102 | 210 | 17570 | 2579 |
SUN1,DOC2A,LAMP1,UNC93B1,KLK10,IL15RA,ATP8A1,HEXB,TGOLN2,LGI3,SYTL4,SNX9,PDGFB,ERP29,PICK1,NCS1,SH3KBP1,AP1M2,P4HB,LMAN2L,STEAP2,CAPG,DNM2,ABCA2,RAB20,PACSIN1,MYRIP,CPE,SMAGP,LAMP3,LAMP2,VPS11,SOD1,SNTB2,ARHGDIB,SLC17A5,MCFD2,ULK2,OPTN,DPYSL3,TRIM9,GPRC5B,DNM1L,WIPI1,AREG,KCNK1,ATP7B,RAB11FIP1,PIK3C2B,ARF6,POMT1,APBA2,NRGN,ANXA11,PCSK5,PIFO,BMF,SERPINE2,HLA-E,HLA-F,RAB23,ATP6V1E2,RACGAP1,RAB6A,APBA1,MARCH8,CALR,RAC2,TIMP1,SNX18,RINL,ZNRF2,OCRL,FCHO1,AHCY,CADPS2,HLA-C,CTSD,WNT3A,GAD1,SYTL3,CCDC88A,CKAP4,TMED2,GPR161,SNX7,KDELR1,C9orf9,KLK5,VEZT,ATP8B3,C3orf58,EGFR,STX3,GNAS,EPN3,AP1AR,HTT,TMEM30A,ITPR1,SH3BP4,RAB31,DYSF,KLK7,ATP1B3,PLD1,TMEM173,RUSC1,PLA2G4A,SLC2A4,GPR107,SLC2A8,BCL2L1,SAYSD1,PHLDA1,BCAP31,APPBP2,SYTL2,CD46,PDGFA,ATP6V0B,N4BP3,SMO,DAB2IP,ECE1,LMAN1,RAB27B,LOXL1,PDIA6,FLOT2,DVL2,EBAG9,CHP1,MYO5B,SEC23A,CLCN3,NRBF2,FZD4,DMTN,SEPT6,SYP,RAB38,GABARAPL1,ATP1A1,STK26,RAB29,SYT13,ABCA1,COPG1,ARFGEF3,ANXA3,SORT1,GOLIM4,HSP90B1,TAOK2,PACSIN2,CD63,BACE1,CTSB,FLOT1,PDIA3,CTSZ,PKN1,HLA-A,FZD6,ITGA2B,PDIA4,KIF5B,CTSC,CDK16,SGK3,CD9,ZDHHC13,ADAM15,SYK,CAMK2G,MYO5A,SYPL1,RAB3B,DENND1B,RAPGEF2,SYBU,GRIN1,VAMP3,FURIN,COL7A1,GGH,AKAP3,FAM109A,FNDC3A,RNPEP,CRISPLD2,HLA-B,NUCB1,LDLRAP1,SERPINA1,CTNS,FGFR2,RAB11FIP2,SYT7,SCG2,CTSV,RIN3,FAM3C,ARRB1,ITGAV,GPER1,FZD5,TBC1D4,OCLN |
| 2.432e-05 | -10.62 | SCHLOSSER_SERUM_RESPONSE_DN | MSigDB lists | SCHLOSSER_SERUM_RESPONSE_DN | 681 | 138 | 17758 | 2588 |
SUN1,BCAM,ATP8A1,HEXB,NDC80,ARFGEF1,PJA2,MAP1LC3B,CALM2,ZFYVE16,BTG3,PSMD1,IL6ST,ATRNL1,RP2,PIK3CD,TRAM1,RASGRP1,LAMP2,SGCE,CD55,DSTN,RNF11,PRKAR2B,MCFD2,SLC25A5,ZFAND5,TRIM9,LRIG1,TDRD7,PIK3C2B,NRGN,NXT2,RUNX2,PPP1R12A,PPP1R2,SEC61G,TBC1D1,PSMD7,CALM3,TXNDC9,COX6C,PHLPP1,FBLN1,PSIP1,RB1,DOPEY2,MEGF8,PAK2,AIM1,RUNDC3B,MSH2,SRP54,NPTN,PIKFYVE,PSMA5,TMED2,NAGPA,MMD,LPGAT1,MICB,CALM1,ZSCAN12,SRSF5,SPTLC2,PSMA4,NT5C2,SERTAD2,INSR,ETS2,DCK,MDH1,CDK18,MAP3K5,TOB1,RAD21,PLA2G4A,NF2,PSME2,CAST,SUZ12,RALBP1,THRA,KTN1,EXT2,SP100,RPN2,ACSL4,MINPP1,CTH,SEC23A,SEC61B,RFK,SEPT6,SLC39A8,SAT1,GLO1,RAD17,GTF2A2,H2AFV,MYL12A,PEX2,STAT1,COBL,PRKAR1A,DYRK3,GNE,PSMD10,HMGN3,CYB561,SIRPA,COX7A2,ZFX,ADD3,PDCD10,CD9,UBE2J1,TFAP2A,HSPA13,SLC35A1,MSH6,NCOA2,SYPL1,ADAM17,ARAP2,DIAPH2,DCTN6,PRDX3,RCBTB2,FGFR2,HNRNPH2,FAM3C,NMI,RYK,CCDC69,ACADM,ATP6V1C1,SRSF9 |
| 2.434e-05 | -10.62 | negative regulation of MAPK cascade | biological process | GO:0043409 | 140 | 40 | 16441 | 2455 |
SPRED1,PINK1,NF2,FOXM1,P2RX7,NDRG2,PSMD10,GSTP1,FBLN1,DUSP5,MECOM,TP73,IGF1R,DACT1,BMP7,RGS3,DLG1,DUSP10,SORL1,DAB2IP,SPRY2,DUSP1,AKT1,TNIP1,ITCH,PBK,EZR,DUSP4,RANBP9,DAG1,C3orf33,LEMD2,PTPRJ,STK38,ARRB1,SPRY4,GPER1,RGS14,F2RL1,HIPK3 |
| 2.449e-05 | -10.62 | IL-4 signaling Pathway | WikiPathways | WP395 | 63 | 24 | 4455 | 729 |
AKT1,INPP5D,PIK3R1,IL13RA1,BCL2L1,CBL,ELK1,ETS1,ADRBK2,RASA1,SOCS3,IRS2,PLCG1,FYN,JAK1,STAT6,STAT1,PIK3CA,PRKCI,MAPK11,HMGA1,PIK3CD,JAK3,SOCS5 |
| 2.452e-05 | -10.62 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN | 193 | 50 | 17758 | 2588 |
PLA2G4A,PPP1R2,SDC4,TP53,KIF23,NDUFA4,PDIA4,TOP2A,CCNA2,KIF14,BDH1,FUT8,DAPK1,CKS1B,RNASEH2A,NFU1,ETHE1,WBP4,ALDH3A2,CKS2,PPIF,NFE2L3,PLK1,TDP1,SOD1,MRPS33,CENPA,LAP3,NRBF2,GGH,KIF20B,BORA,PCTP,CDC25C,CDK1,FRMD4B,PRIM1,BCAR3,DCTN6,PTGS2,H1F0,PRDX3,PRPS2,DBI,RAB11FIP1,CAB39,ADIPOR1,NUP37,NCAPG2,ACOT7 |
| 2.460e-05 | -10.61 | ITGA5 (integrin alpha 5) | protein interactions | 3678 | 38 | 17 | 16036 | 2547 |
LGALS8,SHARPIN,COL18A1,ERBB2,GRK6,FBXO6,CBL,ILK,LGALS3BP,EGFR,CALR,SPP1,ATP1A1,FGFR2,CD9,ATP1B3,L1CAM |
| 2.462e-05 | -10.61 | YNGTTNNNATT_UNKNOWN | MSigDB lists | YNGTTNNNATT_UNKNOWN | 352 | 80 | 17758 | 2588 |
ACVR1,GRHL2,NDC80,WDTC1,CAMK1D,CENPN,TRIM68,C1orf116,SYTL2,WEE1,BTG3,KCTD15,RGS3,LMO4,LHX6,MITF,ATRNL1,DUSP10,ACSL4,PIK3CD,THRB,DOCK4,SMARCA2,COG2,RGAG1,ARHGDIB,KIF13A,ROR1,PPP1R14C,TMTC2,SP4,NFIX,ZNF641,PPP2R5A,RBM47,HOXA9,OVOL1,CTNND1,STARD13,CPEB4,KLHL13,GABRG2,NOTCH2,INTS8,CNTNAP2,SH2D4A,FOXP2,IRAK1,FLRT3,BHLHE41,CALD1,KCNK5,KLF9,CITED2,DLX4,CLIP2,CYP26B1,RASGRF1,BCL9,AMFR,NUB1,PIK3R1,GRIN1,KIF20B,GLT8D2,NFIB,ACADSB,ITPR1,PGRMC1,DCUN1D1,CLMN,AURKA,CEP41,IFIH1,SEMA3A,SHOX2,TOB1,DEF6,DIS3L,WDR63 |
| 2.463e-05 | -10.61 | WINNEPENNINCKX_MELANOMA_METASTASIS_UP | MSigDB lists | WINNEPENNINCKX_MELANOMA_METASTASIS_UP | 153 | 42 | 17758 | 2588 |
SPC25,DLGAP5,PTTG1,NDC80,CDCA8,RACGAP1,NUF2,KIF2C,NANS,CCNB1,CENPN,TOP2A,PCNA,UBE2T,RANBP1,PRC1,NEK2,CKS1B,BUB1,KNTC1,MSH6,CKS2,ZWINT,CENPA,CTNNAL1,ASPM,WHSC1,ANLN,H2AFV,KIF11,CDK1,ARF4,PLOD2,NEIL3,ZNF367,CDCA5,AURKA,KPNA2,DONSON,NCAPG2,CCNB2,MELK |
| 2.463e-05 | -10.61 | MITOTIC_CELL_CYCLE | MSigDB lists | MITOTIC_CELL_CYCLE | 153 | 42 | 17758 | 2588 |
ACVR1,USH1C,DLGAP5,CDKN1C,CIT,NDC80,KIF23,CUL1,KIF2C,NPM2,CDKN2C,BTG3,CCNA2,DLG1,PRC1,NEK2,CDKN1B,KIF22,BUB1,KNTC1,GFI1,CDKN2D,MPHOSPH9,SMC4,PLK1,SUN2,ZWINT,NUSAP1,RAD17,PKMYT1,ANLN,KIF11,CDC25C,CDCA5,E2F1,MAP3K11,AURKA,KPNA2,CENPE,TMEM8B,UBE2C,ESPL1 |
| 2.479e-05 | -10.61 | GSE13306_TREG_VS_TCONV_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_UP | 188 | 49 | 17758 | 2588 |
CDKN1C,TMEM217,FRMD6,CAMKK1,RUSC2,RGS20,GABRG2,HDGFRP2,C3orf18,PHLDA1,FAM167A,FAM46A,TIMP1,ARSG,ZDHHC23,TMEM51,TNFRSF12A,DLG3,S100A13,SMC4,DUSP1,ZNF462,SOD1,PLEKHA6,CELSR2,CRB3,MAPKAPK3,ASXL1,TEF,VAMP3,PPP1R14C,ICMT,ATP10D,ARF4,NFIX,ALDH5A1,KIAA0141,RAB11FIP2,CSF1,NFKBIA,LRIG1,SECTM1,KIAA1804,PRDM5,TDRD7,CDK18,PER3,TRPC3,ACOT7 |
| 2.479e-05 | -10.61 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_DN | 188 | 49 | 17758 | 2588 |
RECQL,TNRC6C,ADD1,ST14,GALNT12,ARL4C,NDRG2,TEX2,TRMT2B,GRK6,ETS1,BMP2K,PDIA4,DTX3L,RCN1,NUP210,SRR,FAM102A,F2R,TPCN1,RPGR,FGFR1OP2,RASGRP1,HP1BP3,PHF20L1,PTPN9,USP18,SPATA13,MYBL2,HMG20B,SKA1,UAP1,RBL1,DCK,LIMK1,PRPS2,C1orf21,STAT1,TRIOBP,PPM1H,RNASEL,ARHGAP4,NCAPG2,CBX5,GEN1,ESPL1,CBX4,IRF1,PRKAR1A |
| 2.494e-05 | -10.60 | regulation of multicellular organismal development | biological process | GO:2000026 | 1553 | 288 | 16441 | 2455 |
ACACB,ACVR1,SSH1,LGR4,TSC22D3,RET,GATA3,PLXNA1,CAMK1D,CCNB1,VASH1,FAM101B,GRM5,NCS1,TP73,CTGF,DNM2,TACSTD2,SEMA3G,PACSIN1,TIAM1,ACVR1C,TFAP2C,LOXL2,SAV1,POR,ULK2,ENPP1,PLCG1,PLK2,LIMK1,TBX1,TRAF3IP1,NKD1,BMP1,ITPKA,ARF6,HSPB1,LZTS1,SEMA6B,SOX9,PRKAA1,ZNRF3,BMP2K,CALR,ITGA3,CYR61,MEGF8,FLRT3,VASN,FBXO7,SORL1,TNFRSF12A,MYDGF,MAPK7,RIMS2,GPR161,SOCS5,EPB41L5,MMD,ANO6,WHSC1,KIF20B,EPHA1,NPHP3,ILK,GNA11,NFIB,RHOB,FAS,PTPRF,NCOA3,SEMA4D,NAB2,SFMBT1,EFNA1,GDF11,XDH,EGLN1,IRF1,FOXO6,GRHL2,LFNG,INPP5D,EGR3,PRKACA,FLT3,TNFSF9,CCND1,CD46,SP100,CDKN1B,DAB2IP,ETV4,SEMA3B,SSH3,RIPK2,CLSTN1,HTATIP2,FZD7,FYN,AXL,WWTR1,SIPA1L1,INPP4B,STAT1,NRG1,RAB29,RGS14,ARNT,COBL,WASF3,CTHRC1,NKX3-1,FLOT1,ETS1,SRPX2,ADGRB2,SIX4,CTNNBIP1,PDCD10,PTEN,KNDC1,BAX,MAPK11,CITED2,RAG1,GFI1,ITM2C,TRIM62,MSH6,TGIF1,RAPGEF2,PIK3R1,GRIN1,FOS,CDK5RAP1,BTG1,PROM1,FGFR2,ACVRL1,NR1D2,TBX18,ERAP1,GPER1,OSR1,ARSB,SHOX2,FOXA1,EMX1,AGRN,EPHA4,PHOSPHO1,PDGFB,CTNNB1,CDKL5,IL6ST,DPYSL2,MITF,DLG1,DUSP10,NTN4,CTTN,RASGRP1,CYP1B1,SOD1,ITCH,ARHGDIB,KLK6,EAF2,CDK1,RHEB,DPYSL3,IRX3,GPRC5B,HPSE,HOXA9,SP6,MAFF,GRN,RUNX2,PPP1R12A,LGALS3,SERPINE2,UBASH3B,ETV5,PHLPP1,BMP2,SPP1,RB1,CA2,TIMP1,GATA2,FAM20C,KIF13B,PRKCI,FNIP1,NPTN,WNT3A,NTN1,CCDC88A,HMG20B,KIAA1109,CDK5R1,SOX13,GNAS,INSR,TMEM30A,CSF1,NFKBIA,FAM213A,JAK3,SEMA3A,RARG,GAS2L1,PAX6,HOXB7,NF2,IL15,TP53,ERBB2,P2RX7,IL27RA,OSR2,EMP2,PER2,PDGFA,KIF14,SMO,BCL6,CDH3,TWIST1,DIXDC1,TMEM64,NOTCH3,DVL2,TIMP2,AKT1,CDC20,CCSAP,CD40,DAG1,ARHGAP35,PTGS2,BHLHB9,STAT6,PTK7,IRF7,EFNA5,PLXND1,CTDSP1,BIN1,ANXA3,ADGRG1,CIT,LRP4,TGFBR1,CRABP2,PPP2R3A,FZD6,HDAC9,CD109,MYCL,BMP7,KIAA0319,TFAP2A,H2AFY,IQGAP3,SYK,TLE6,FAM134C,HES1,RHOA,WNT10B,ASPM,RGCC,PRICKLE1,CD83,MAP1B,HLA-B,DDAH1,FAT4,FGF18,PPP2R3C,SOX8,NDFIP1,L1CAM,NGEF |
| 2.503e-05 | -10.60 | Innate Immune System | REACTOME pathways | R-HSA-168249 | 752 | 153 | 8202 | 1235 |
SIGIRR,UNC93B1,TXN,NRG2,CUL1,PSME1,ITPR2,PDGFB,SPTB,CALM2,PSMD1,RPS6KA2,CTNNB1,ELMO2,SHC3,PSMC2,PIK3CA,DNM2,DUSP10,IRF2,PIK3CD,RASGRP1,NLRP4,CD55,ITCH,CASP9,AGO4,PRKAR2B,PLCG1,LIMK1,MAP3K11,NOD2,MAPK13,PPP2R5D,PSMC1,GAB1,DDX58,LGALS3,HLA-E,RASA2,PSMD7,CALM3,TEC,NCKAP1,PHLPP1,DUSP5,PAK2,HLA-C,NCAM1,MAPK7,PSMA5,MAPKAPK3,CALM1,CYFIP2,ELK1,PSMA4,EGFR,RASA1,RASGRP2,MAPKAPK2,PHLPP2,PELI2,NFKBIA,ITPR1,NLRC5,PLD1,ARPC2,JAK3,IFIH1,RPS6KA3,TMEM173,IRF1,SPRED1,NLRX1,PSME2,IQGAP1,RPS6KA1,P2RX7,ERBB2,RASGRP3,BCL2L1,PRKACA,PDGFA,CD46,PLCG2,CDKN1B,DAB2IP,LGMN,RASGEF1A,NFKB2,FRS3,AKT1,RIPK2,PRKCQ,DUSP4,ITPR3,CASP4,IRS2,FYN,JAK1,PPP2R5A,DDOST,STAT6,PSMD3,NRG1,IRF7,SPTBN5,MAPK12,PRKAR1A,OTUD5,WASF3,HSP90B1,TNRC6C,TAB3,CTSB,TRAF2,HERC5,PSMD10,PLD2,FGF19,ITGA2B,ADRBK1,IRAK1,PTEN,TRIM21,MAPK11,ERBB3,MAP3K7,CNPY3,SYK,MYO5A,CAMK2G,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,GRIN1,YES1,PELI3,FOS,BCL10,TXK,CTSL,HLA-B,FGFR2,FGF18,CTSV,UBE2D2,DTX4,ARRB1,GRIN2D |
| 2.504e-05 | -10.60 | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | 87 | 28 | 17758 | 2588 |
LOC81691,DYRK3,CDKN1C,ATP9A,ARL4C,TP53,EZR,TP53I11,NPC2,CYFIP2,ILK,DHRS3,CASP4,CARD10,CDK14,STK17A,ITGA3,PDLIM3,AXL,STAT1,DAPK1,SH3BP4,ACTA2,CTNND1,RGS5,PIK3CD,GEM,PTPRE |
| 2.504e-05 | -10.60 | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | 87 | 28 | 17758 | 2588 |
CD55,CASP9,BNIP3L,COL18A1,MAP1LC3B,RHOB,ARHGAP35,GNAS,PTPRF,PSMD1,GPRC5B,CDK16,GDE1,P4HA2,FDXR,ITPR1,PGRMC1,RAB31,TMBIM6,SGK1,PDXK,MAP3K7,PHKA2,MAP3K5,PLIN3,ATP2B1,PRKAR1A,DUSP1 |
| 2.522e-05 | -10.59 | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP | 173 | 46 | 17758 | 2588 |
CCNC,AVPI1,TMEM184B,SLC16A14,SEC61G,PDIA5,CYB561,ZMYND10,GSTP1,IL17RB,SETDB2,PAPSS1,PSMC2,CST3,SGK1,VAT1,TECR,TSPAN1,CCDC88A,WBP5,C9orf9,RAPGEF2,SLC39A8,SYNE2,MYEOV,ZKSCAN2,PRKRA,PCTP,TP53I3,RANBP9,PRDX4,GABARAPL1,CXXC4,TSC1,IDE,UAP1,COL13A1,ABHD12,P4HA2,LRIG1,FAM114A1,DYSF,SPCS3,ALG2,APBA2,CBX4 |
| 2.528e-05 | -10.59 | Insulin receptor signalling cascade | REACTOME pathways | R-HSA-74751 | 280 | 68 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,DUSP4,RHEB,IRS2,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,CAB39,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,CALM3,PSMD10,FGF19,DUSP5,ITGA2B,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,PSMA4,EGFR,RASA1,TSC1,PRKAG2,INSR,FGFR2,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.532e-05 | -10.58 | MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | MSigDB lists | MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | 61 | 22 | 17758 | 2588 |
ARHGEF3,GCLC,PTTG1,SOD2,GATA3,TCF7,IFIT3,IDH1,PHLDA1,EDNRA,CDH1,AREG,SPINT2,BCL6,CD9,DAPK1,CLDN4,KLF5,ERBB3,RAB27B,NFKB2,SLC12A2 |
| 2.556e-05 | -10.57 | TGACCTY_V$ERR1_Q2 | MSigDB lists | TGACCTY_V$ERR1_Q2 | 978 | 188 | 17758 | 2588 |
SLC25A13,FHDC1,NDRG2,OAT,DNER,DENND2D,LTBP3,SLC9A7,NKAIN3,CYP1A1,RPS6KA2,CDKL5,STIM1,IMPAD1,RGS3,MITF,STEAP2,SERINC2,CLDN4,MANF,PACSIN1,ANO4,WBP4,BTBD3,CCDC38,CXXC5,ASXL1,CBX6,NFE2L1,SLC25A5,CLCN2,RNF19B,PNKD,ABR,PGF,SLC25A4,KLF12,KCNK1,MYLK,MADD,MRPS28,PIEZO1,SPRY4,ARF6,ITPKA,APBA2,SLC31A2,RTN3,HOXC13,DLAT,NR2C2,PCSK5,RRAGD,SCN5A,SLC25A27,C6orf106,FAM81A,FBLN1,HPCAL4,TSPAN7,MECOM,ELF3,DAZAP1,VASP,CA2,SLC16A6,RANBP1,NEK2,SORL1,TNFRSF12A,RFX5,PIM1,CTSD,ZRANB1,DLX4,RIMS2,TRAK2,SPATA20,WDR72,USP31,DCHS1,STRADB,TCF7,BCL2L13,RASGRP2,BCAR3,EPN3,INSR,ITGA7,C1orf21,SLC4A3,DCUN1D1,S100A5,MPP2,NXPH4,MDH1,KLF7,DMPK,NCKAP5,SLC2A4,PAX6,CAPN12,UGP2,TRIP10,DDIT4L,XYLT1,BLCAP,OSR2,FAM198B,PRR7,CYP39A1,ZFYVE9,EPS8L2,C1orf116,CDK14,ST5,ZNF687,SCNN1A,DOK4,XYLT2,DACT1,BCL6,GOT1,APIP,NR2C1,TMEM43,AGPS,SAT1,PANK1,KIF1C,ATP1B1,PDHX,GABARAPL1,NFIX,PPP1CB,ADAMTS14,NRG1,RCAN2,PLXND1,ANXA9,AIFM3,ST3GAL1,LIFR,SORT1,TM2D2,TAB3,SLC41A1,GABRG2,PDIA3,CRABP2,PKN1,PPP2R3A,SIRPA,XPR1,ZDHHC21,IRF2BPL,CCDC92,KIF5B,CEP97,CDK16,KCNK5,RRBP1,ADAM15,WWP1,TAGLN2,OSGIN1,NCOA2,CAMK2G,FBLN5,LCA5,BCL9,OGDHL,UBAC1,PIM3,CRISPLD2,MAP1B,ARHGAP24,PITX2,TMEM50B,RND3,CCDC69,FHL1,NDFIP1,ZBTB33,FOXA1,SNPH,JARID2,TLL2 |
| 2.590e-05 | -10.56 | MODULE_137 | MSigDB lists | MODULE_137 | 526 | 111 | 17758 | 2588 |
TRIM2,PAX6,EPAS1,CRYM,THRA,EPHA4,TMX4,CACNA2D2,C5orf30,NRG2,BAIAP3,PLA2G16,APC2,PHLDA1,PHYHIP,SRPX,TACC2,CABP1,LMO4,ALDH1A3,RGS5,ARNT2,IFIT1,BTBD3,CPE,HSPA2,TMCC2,SGCE,MBP,COL6A2,CBX6,KLK6,ROR1,ATP1B1,LDB2,ALCAM,PLEKHB1,FZD7,DPYSL3,MDK,TRIM9,GPRC5B,MAP2,KCNK1,MYLK,TLE1,MAOA,RCAN2,SERPINI1,ITPKA,APBA2,NRGN,BIN1,WASF3,COL9A3,CDH22,IGFBP6,ENO2,ATP9A,ITGA6,DNAJB2,CALB2,SOX9,GABRG2,SLC1A3,CNTNAP2,SEPP1,TSPAN7,DUSP5,PARM1,RND1,NEO1,ELF3,DIRAS3,SPP1,CA2,NECAB3,GPC3,RIMS3,BDH1,IGFBP2,ALDH7A1,HSPA13,NCAM1,GAD1,TTLL1,RIMS2,EPHX1,FADS2,NR4A1,GRIN1,DPYSL4,FOS,RHOB,TIMP3,SERPINA1,DGCR2,SCG2,FGFR2,RND3,ITGA7,ITPR1,TCEAL4,RAB31,STK39,CDK18,L1CAM,CSRP2,PKIA,SNPH,ARHGEF4 |
| 2.601e-05 | -10.56 | CYTOSKELETON | MSigDB lists | CYTOSKELETON | 358 | 81 | 17758 | 2588 |
MYL9,KIF3C,SORBS1,NF2,DLGAP5,TUBB4B,IQGAP1,KLC2,KIF2C,CNTROB,HDAC6,SPTB,APPBP2,CDH1,CTNNB1,CNTRL,CABP1,CAPG,ABCA2,TUBG1,ESPN,EPB41L4B,CTTN,NEB,ATG4D,PLK1,PCGF5,MARK1,UXT,CDC20,UTRN,EZR,ARHGDIB,ANLN,MYOM1,CDK1,DAG1,NIN,MAP2,SHROOM3,CORO1C,MAP3K11,HSPB1,BIN1,LASP1,FARP1,BMF,KIF23,SAC3D1,ATG4A,CKAP5,TOP2A,KIF5B,VASP,CALD1,TBCD,TUBGCP6,PRC1,DAPK1,NEK2,BUB1,KNTC1,CLIP2,DNAI1,CASK,KIF20B,AIF1L,KIF11,RANBP9,ABLIM2,MAP1B,KLHL2,TSC1,AURKA,PKD2,CEP41,NDE1,ARPC2,CCNB2,SHROOM2,ESPL1 |
| 2.607e-05 | -10.55 | response to oxygen-containing compound | biological process | GO:1901700 | 1463 | 273 | 16441 | 2455 |
TXN,SSH1,RET,NRG2,GATA3,PSME1,IL18,CCNB1,CALM2,CYP1A1,SESN3,PSMD1,TGFBR3,CTGF,KLF3,FOSB,PIK3CA,DNM2,CLDN4,ACVR1C,CASP9,PRKAR2B,POR,ABR,ENPP1,AREG,TBX1,NOD2,EIF4EBP2,GAB1,KLF2,INPPL1,DGKQ,SOX9,PRKAA1,TFAP4,CALR,NCAM1,MAPK7,MAPKAPK3,MICB,CALM1,ERO1A,CALCRL,ELK1,MEST,PSMA4,RHOB,RASA1,FAS,MMP15,IL1R1,NCOA3,PRKAG2,DGAT2,AURKA,NR4A2,MAP3K5,TRPC3,RPS6KA3,EGLN1,SPRED1,SLC2A4,NQO1,WDTC1,BCL2L1,PRKACA,GNB2,CCND1,CCNA2,CDH1,SP100,CDKN1B,DAB2IP,PDE4D,LRP11,OSBPL7,RASGEF1A,CDKN2D,COL6A2,RIPK2,FZD4,PFKFB2,DMTN,PRKCQ,FZD7,IRS2,FYN,JAK1,CDK19,STK26,AXL,STAT1,SLC27A1,NRG1,PRKAR1A,OTUD5,HSP90B1,NKX3-1,PLSCR4,TRAF2,EPS8,ETS1,GSTP1,FGF19,ICAM1,CAPN2,CXCL16,PDCD10,IRAK1,OXCT1,PTEN,CST3,BAX,CD9,TMBIM6,IGFBP2,ERBB3,GFI1,HCN3,RASGRF1,PDGFC,SHMT1,RAPGEF2,PIK3R1,GRIN1,YES1,FOS,GPLD1,BTG1,TIMP3,FGFR2,RAB11FIP2,PRDX3,NR4A3,OSER1,GRIN2D,GPER1,CMPK2,OSR1,CPEB2,FOXA1,PHC1,CASP3,ITPR2,HDAC6,SDC1,PDGFB,SPTB,RPS6KA2,CTNNB1,P4HB,SHC3,DPYSL2,PSMC2,AKR1B1,DUSP10,TNFRSF18,ARNT2,RASGRP1,CYP1B1,SOD1,ASXL1,EZR,RHEB,MAP2,CAB39,PSMC1,RRAGD,GRN,PRKAA2,RASA2,PSMD7,ATP6V1E2,CALM3,DUSP5,SPP1,IGF1R,TIMP1,PFKL,COL6A1,PRKCI,PIM1,WNT3A,PSMA5,OXR1,STRADB,PDK3,EGFR,MAPKAPK2,GNAS,FECH,TSC1,INSR,NFKBIA,SH3BP4,RAB31,JAK3,RARG,COL16A1,DRD1,SORBS1,IL15,FOXM1,PSME2,SLC2A8,SOD2,P2RX7,ERBB2,COL18A1,RASGRP3,SDF4,PDGFA,ATP6V0B,PLCG2,SRR,SMO,GOT1,NFKB2,LOXL1,F2R,FRS3,PPIF,SIRT1,AKT1,PTGER4,ERBB2IP,CD40,DAG1,CASP4,SOCS3,PTGS2,DUOX1,ATP1A1,IDE,PTK7,PSMD3,SPTBN5,LTA4H,ABCA1,SORT1,CPEB4,CTSB,SELL,PSMD10,TGFBR1,HDAC9,BMP7,TFAP2A,HMGCL,KLF9,MYO5A,CAMK2G,DUSP1,GCNT1,P2RX4,RHOA,ADAM17,WNT10B,PSMB4,NR4A1,PPARA,LITAF,GGH,BCAR1,CTSV,FGF18,E2F1,PKD2,HOXB13,ATP6V1C1,TBC1D4,PTGES |
| 2.613e-05 | -10.55 | KERLEY_RESPONSE_TO_CISPLATIN_UP | MSigDB lists | KERLEY_RESPONSE_TO_CISPLATIN_UP | 41 | 17 | 17758 | 2588 |
DDB2,INPP5D,DGKA,GDF15,ISYNA1,SESN1,LMNA,EPS8L2,FAS,STK17A,IER3,ANK1,PLK2,ALDH1A3,FDXR,DRAM1,ACTA2 |
| 2.638e-05 | -10.54 | protein kinase inhibitor activity | molecular function | GO:0004860 | 56 | 21 | 16491 | 2452 |
CASP3,SPRED1,CDKN1C,IBTK,DNAJC3,PRKAR2B,TRIB2,MAPK8IP1,SOCS3,CDKN2C,CAMK2N2,PRKAG2,H2AFY,CDKN1B,HEXIM2,HSPB1,CDKN2D,SPRY2,PKIA,PRKAR1A,CHP1 |
| 2.640e-05 | -10.54 | antigen processing and presentation of endogenous peptide antigen | biological process | GO:0002483 | 11 | 8 | 16441 | 2455 |
HLA-B,TAPBP,HLA-E,TAP1,ERAP1,HLA-C,HLA-A,ERAP2 |
| 2.653e-05 | -10.54 | breast-other-adenosis | COSMIC cancer mutations | breast-other-adenosis | 30 | 14 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,GNA11,EGFR |
| 2.653e-05 | -10.54 | adenosis | COSMIC cancer mutations | adenosis | 30 | 14 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,GNA11,EGFR |
| 2.719e-05 | -10.51 | PID_AURORA_A_PATHWAY | MSigDB lists | PID_AURORA_A_PATHWAY | 30 | 14 | 17758 | 2588 |
CENPA,DLGAP5,AKT1,TACC1,ARHGEF7,NFKBIA,TDRD7,TP53,AURKA,AURKB,PRKACA,PPP2R5D,RASA1,CKAP5 |
| 2.733e-05 | -10.51 | MODULE_403 | MSigDB lists | MODULE_403 | 45 | 18 | 17758 | 2588 |
CCNE2,PLK1,CENPA,CDC20,MYBL2,CCNB1,CDK1,TRUB1,TOP2A,WEE1,PCNA,PLK4,E2F1,MSH2,NEK2,XRCC3,KPNA2,MELK |
| 2.743e-05 | -10.50 | actin cytoskeleton organization | biological process | GO:0030036 | 399 | 90 | 16441 | 2455 |
SORBS1,NF2,SSH1,ADD1,TMSB15A,TRIP10,TESK2,F11R,MRAS,MICALL2,FAM101B,EMP2,TMSB15B,PDGFA,PAK6,ZYX,FRYL,DLG1,BCL6,ESPN,CTTN,MYH14,EPB41L4B,PACSIN1,DMTN,DSTN,EZR,ARHGDIB,ABR,LCP1,DPYSL3,PDLIM3,SHROOM3,PTK7,LIMK1,CORO1C,SIPA1L1,TRIOBP,PRKCDBP,TMOD2,SPTBN5,ARF6,ITPKA,COBL,FGD1,PRKAR1A,WASF3,INPPL1,HSP90B1,USH1C,PACSIN2,TAOK2,ARHGEF11,EPS8,SORBS3,RACGAP1,NCKAP1,SIX4,CORO1B,RND1,CALR,FLII,RAC2,VASP,PDCD10,FRY,LLGL2,PAK2,PRKG1,PRKCI,LIMCH1,FARP2,EPB41L5,RHOA,FMN1,CORO2A,FBXO8,STRADB,DIAPH2,PLS1,ANTXR1,BCAR1,ABLIM2,SWAP70,RND3,ARAP1,FGD6,ARRB1,ARPC2,SHROOM2 |
| 2.759e-05 | -10.50 | Signaling by SCF-KIT | REACTOME pathways | R-HSA-1433557 | 307 | 73 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,PTPRU,CASP9,AGO4,DUSP4,CBL,IRS2,FYN,PPP2R5A,JAK1,PSMD3,STAT1,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,TEC,PHLPP1,FGF19,DUSP5,ITGA2B,PTEN,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,YES1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.764e-05 | -10.50 | POST_TRANSLATIONAL_PROTEIN_MODIFICATION | MSigDB lists | POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 470 | 101 | 17758 | 2588 |
TNK1,ACVR1,NF2,SSH1,HDAC11,RET,ERBB2,TESK2,MAPK4,HDAC6,EPM2A,PICK1,CCND1,DAPK2,CDKL5,PPME1,IL31RA,PLK4,DUSP10,PPP1CA,F2R,PTPRE,METAP2,MAP3K3,SIRT1,NEK4,PTPN18,MARK1,AKT1,PTPN9,RNF11,DUSP4,ICMT,CBL,MAP3K6,STK17B,PTPRJ,LIMK1,STK38,MYLK,PPP2R4,KIAA1804,STAT1,MAP3K11,PCSK5,MAPK12,PRKAA2,CDK17,PINK1,DYRK3,PRKAA1,TGFBR1,TRIB2,SBF1,PKN1,MERTK,DUSP5,PPP2R3A,IGF1R,PTEN,CDK16,PAK2,SGK3,MAP3K9,DAPK1,TPST1,PRKG1,PRKCI,SGK1,WWP1,PIM1,ERBB3,MYLIP,GAD1,CCDC88A,DDB2,QSOX1,AMFR,PTPRH,FURIN,STRADB,EIF2AK1,ILK,EGFR,NMT2,PRDX4,TXK,BCL10,STK17A,MAPKAPK2,TSC1,INSR,ACVRL1,NR4A3,AURKA,UBE2C,CD81,JAK3,CTBP1,HIPK3,DMPK |
| 2.799e-05 | -10.48 | HALLMARK_INTERFERON_GAMMA_RESPONSE | MSigDB lists | HALLMARK_INTERFERON_GAMMA_RESPONSE | 199 | 51 | 17758 | 2588 |
DDX58,PLA2G4A,CASP3,PARP12,IL15RA,IL15,PARP14,PSME2,TAP1,SOD2,PSME1,CD274,HERC6,LGALS3BP,HLA-A,ICAM1,TRIM21,IRF2,IFIT1,OAS3,PIM1,MX1,RIPK2,PLSCR1,LAP3,IFITM3,USP18,STAT4,IFIT3,CD40,CASP4,SOCS3,FAS,HLA-B,BTG1,NCOA3,TAPBP,PTGS2,CASP7,BANK1,NMI,SECTM1,NFKBIA,STAT1,TDRD7,NLRC5,IRF7,CMPK2,IFIH1,ISOC1,IRF1 |
| 2.801e-05 | -10.48 | BURTON_ADIPOGENESIS_8 | MSigDB lists | BURTON_ADIPOGENESIS_8 | 83 | 27 | 17758 | 2588 |
CD99,LAMP2,ANXA3,PRSS23,DSTN,KDELR3,EMP3,ASAH1,COL4A5,FAM91A1,MAP1LC3B,PRDX4,MAPKAPK2,TAPBP,TIMP3,TSPAN6,CAPG,BAX,RAB31,FXYD5,ACTA2,SERPINB6,CTSA,ITGAV,NCAM1,F2R,WBP5 |
| 2.843e-05 | -10.47 | GSE27786_NKTCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_NKTCELL_VS_MONO_MAC_DN | 194 | 50 | 17758 | 2588 |
CASP3,CPEB4,CPT2,IQGAP1,NDC80,ERCC6L,FLOT1,SLC36A4,RBP7,FLT3,VPS26A,ELF3,KIF5B,VASP,ZNF687,FAM160A2,PRC1,TAX1BP3,RAB20,APIP,KNTC1,ACOX2,IQGAP3,TRAK2,CYP1B1,AMOTL2,HMMR,SUN2,MLEC,KIF20A,PARD3B,LPGAT1,STRADB,CKAP2L,ARHGEF26,CMTM7,OPTN,KLHL2,BCAR3,MID1IP1,WIPI1,PELI2,NETO2,TDRD7,EGFL7,PKD2,GDF11,NCAPG2,SRSF9,NIPA1 |
| 2.843e-05 | -10.47 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN | 194 | 50 | 17758 | 2588 |
CASP3,MTM1,SORBS1,TXN,LGALS3,S100A11,SEC61G,SERPINB9,PTTG1,EFHD2,RACGAP1,IL18R1,SLC35E4,KCTD9,HLA-A,CAPN2,DAPK2,RRBP1,MDFIC,CTSD,F2R,SNX10,S100A13,S100A6,PLSCR1,SNTB2,S100A4,DSTN,LITAF,EMP3,GGH,DOCK5,RNF19B,ALCAM,CASP4,PRDX4,GALNT3,NUCB1,CARHSP1,ENPP1,IDE,CASP7,H1F0,NR4A2,ALG2,ARF6,CCNB2,CHPT1,ACOT7,XDH |
| 2.858e-05 | -10.46 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | 573 | 119 | 17758 | 2588 |
CCNC,ST13,UGP2,CNOT8,CUL4B,ETNK1,XIAP,PDIA5,ARFGEF1,CUL1,TGOLN2,PIGL,MAP1LC3B,PCBP1,CD46,TM9SF2,RALB,FICD,ARL1,GYS1,IRF2,RPN2,ASH2L,OAS3,LGMN,TFG,PXMP4,LMAN1,WBP4,PTPRE,TRAM1,CTDSP2,CLCN3,LAP3,SLC39A8,CDYL,UTRN,VPS4B,MRPS35,SLC17A5,CD40,SLC25A5,ADRBK2,PDHX,LCP1,ARF4,OPTN,TRAM2,JAK1,DDOST,GDE1,PTER,CBX4,ANXA11,ZNF395,PPP1R2,CD63,ARHGEF7,ARL4C,ASAH1,PBX3,GMCL1,TXNDC9,AIP,DUSP5,DNAJB9,M6PR,KIF5B,RAC2,PDCD10,PTEN,PRKCI,TMBIM6,ECI2,USP1,NPTN,MAP3K7,MYLIP,SLC12A2,ALDH3A2,SYK,PSMA5,TMX1,MCCC2,CKAP4,MYO5A,P2RX4,PGM1,RC3H2,PARP4,AK4,PDK3,ILK,RHOB,NMT2,FAS,PRDX4,STK17A,CNOT2,DCTN6,CASP7,PRDX3,RCBTB2,CCDC6,SEMA4D,PRCP,NAT1,SLC25A40,ITPR1,UBE2D2,PGRMC1,CSTF2,PITPNA,RPS6KA3,PKIA,USP16,XDH,EGLN1,ABCG1 |
| 2.858e-05 | -10.46 | IGF1R signaling cascade | REACTOME pathways | R-HSA-2428924 | 281 | 68 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,DUSP4,RHEB,IRS2,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,CAB39,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,CALM3,PSMD10,FGF19,DUSP5,ITGA2B,IGF1R,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,PSMA4,EGFR,RASA1,TSC1,PRKAG2,FGFR2,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.858e-05 | -10.46 | IRS-related events triggered by IGF1R | REACTOME pathways | R-HSA-2428928 | 281 | 68 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,DUSP4,RHEB,IRS2,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,CAB39,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,CALM3,PSMD10,FGF19,DUSP5,ITGA2B,IGF1R,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,PSMA4,EGFR,RASA1,TSC1,PRKAG2,FGFR2,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.858e-05 | -10.46 | Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | REACTOME pathways | R-HSA-2404192 | 281 | 68 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,DUSP4,RHEB,IRS2,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,CAB39,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,CALM3,PSMD10,FGF19,DUSP5,ITGA2B,IGF1R,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,PSMA4,EGFR,RASA1,TSC1,PRKAG2,FGFR2,FGF18,ARRB1,GRIN2D,JAK3 |
| 2.859e-05 | -10.46 | plasma membrane raft | cellular component | GO:0044853 | 87 | 28 | 17570 | 2579 |
SPRED1,SCN5A,PACSIN2,CTSB,LRP4,FLOT1,EZR,ATP1B1,CBL,HDAC6,PRKACA,EMP2,PTGS2,INSR,ATP1A1,IGF1R,CDH1,CTNNB1,CORO1C,SMO,PRKCDBP,SLC27A1,EFNA5,ATP1B3,FLOT2,F2R,DRD1,PRKAR1A |
| 2.859e-05 | -10.46 | vacuolar lumen | cellular component | GO:0005775 | 87 | 28 | 17570 | 2579 |
LAMP2,GAA,AGRN,HSPG2,GUSB,CTSB,HEXB,SDC4,ASAH1,SDC1,TCN2,ATP13A2,DAPK2,FUCA1,CTSL,GNS,SCARB2,HPSE,GPC3,CTSV,GALNS,GLB1,CTSA,GLA,CTSD,LGMN,ARSB,GM2A |
| 2.880e-05 | -10.45 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN | 189 | 49 | 17758 | 2588 |
ELK4,KLF2,KCNAB3,ALDH6A1,ATP8A1,ELOVL7,MCOLN3,ARL4C,SELL,C1orf198,ZNRF3,SNN,TSPAN17,CYP39A1,TMCC3,RPS6KA2,FRY,SLC44A1,SLC44A2,IL17RA,MAPK11,FAM84B,C9orf72,MCCC2,ATP2B1,EPHX1,TEF,LRRC66,PDE5A,TRIM35,TCF7,AKAP3,RAB3IP,TANC1,FOS,ATP10D,RASA1,NFIX,FOXD2,NAAA,MID1IP1,PAPD5,C1orf21,APPL2,HS3ST3B1,TMEM8B,USF2,NIPA1,KLF7 |
| 2.880e-05 | -10.45 | GSE3982_MAST_CELL_VS_NKCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_UP | 189 | 49 | 17758 | 2588 |
PLA2G4A,LAMP1,ACVR1,SORBS1,ARAP3,TRIM24,EPAS1,ADO,ETV5,ERI2,GMPR,NDRG2,NDUFA4,MGST2,SNN,ECI1,LMNA,M6PR,PSMD1,ITGA3,FRY,LMO4,MITF,PRKCI,DRAM1,DUSP10,RAB20,ITM2C,HSPA2,KCTD3,CKS2,METAP2,SOCS5,MCTP1,MCFD2,IDH1,PCTP,SGPP1,IL1R1,RPL12,TIMP3,PRDX3,H1F0,TCEAL4,PPM1H,TBC1D4,TMEM14A,RTN3,ABCA1 |
| 2.880e-05 | -10.45 | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 189 | 49 | 17758 | 2588 |
DDX58,SLC25A24,ARHGEF3,UGP2,DLGAP5,ITGA6,SMARCAL1,NUF2,TXNDC9,NCKAP1,VASH1,NUDT12,HMGXB4,SYTL2,TOP2A,FAM46A,SNX18,FAM13B,TRIM21,C2orf72,USP38,LGMN,F2R,TRAM1,SNX10,RASGRP1,NCOA2,FAM69A,MOB4,TAF5,ASPM,TMEM98,NUSAP1,ANLN,GOLT1A,KIF11,C4orf27,ATP10D,FYN,IDE,PLEKHH2,CASP7,RBL1,NR4A3,IRF7,RELL1,SGOL1,CBX5,ESYT2 |
| 2.881e-05 | -10.45 | biological adhesion | biological process | GO:0022610 | 1040 | 202 | 16441 | 2455 |
MYL9,BCAM,KIAA1462,EPHA4,RET,GATA3,F11R,EPDR1,LYPD5,EPCAM,ZYX,MUC4,CTNNB1,CTGF,NPNT,ELMO2,DLG1,CLDN4,PIK3CD,TINAGL1,CTTN,TLN2,TIAM1,SMAGP,CYP1B1,SGCE,CELSR2,TNIP1,EZR,LOXL2,LCP1,COL12A1,HPSE,CTNND1,TMEM8B,ARF6,HSPB1,F2RL1,CD99,RUNX2,INPPL1,NUAK1,THEMIS2,BVES,ITGA6,HLA-E,SOX9,SORBS3,CNTNAP2,APBA1,MERTK,IL18R1,SSX2IP,SPP1,RAC2,ITGA3,LRRN2,CYR61,LYPD3,CD22,ICAM5,FLRT3,KIF13B,COL6A1,CTPS1,TNFRSF12A,NPTN,NCAM1,TMEM8A,NTN1,WNT3A,SNED1,EPB41L5,PODXL2,PCDH1,RGMB,MICB,DCHS1,SCRIB,VEZT,EPHA1,CYFIP2,ILK,ANTXR1,RHOB,EGFR,CDK5R1,FAS,GNAS,PTPRF,TSC1,SCARB2,SEMA4D,PVRL2,COL13A1,PLPP3,ITGA7,CGREF1,PCDH19,EGFL7,EFNA1,AKIP1,COL16A1,IRF1,SORBS1,GRHL2,LFNG,IL15,CERCAM,TP53,P2RX7,TESK2,PKP2,COL18A1,MICALL2,FLT3,EMP2,DDR1,NOV,MUC16,CDH1,SRPX,KIF14,CDH3,EPHB4,FLOT2,CAMSAP3,COL6A2,RIPK2,FZD4,PTPRU,PTGER4,CLSTN1,ATP1B1,ERBB2IP,ALCAM,MYL12A,DAG1,FZD7,FYN,DDOST,AXL,STAT6,PTK7,ANXA9,RPL22,FBLIM1,TAOK2,CDH22,CD63,ADGRG1,HAPLN3,ARHGEF7,GNE,BTN3A1,CBLL1,SELL,JAG2,EFNB1,SRPX2,LGALS3BP,ICAM1,NRP2,SIRPA,ITGA2B,NEO1,ITGB8,IGSF9,BMP7,BAX,CD9,ARVCF,ADAM15,RAG1,SYK,FARP2,GCNT1,PVRL4,HES1,ADAM17,RHOA,CASK,FBLN5,CTNNAL1,RC3H2,VAMP3,PLEKHA7,COL7A1,FNDC3A,BCAR1,TXK,CNTNAP1,CD8A,FAT4,DGCR2,RND3,ITGAV,ICOSLG,FZD5,CD81,L1CAM,CD33 |
| 2.883e-05 | -10.45 | establishment of localization in cell | biological process | GO:0051649 | 1843 | 335 | 16441 | 2455 |
DOC2A,LAMP1,ACACB,IBTK,GRIK2,SLC25A13,KLC2,TAP1,GATA3,TRAPPC8,TGOLN2,LGI3,BAIAP3,SYTL4,CCNB1,SNX9,RIC1,PICK1,CALM2,NAPG,AP1M2,CTGF,STEAP2,DNM2,SNX16,TINAGL1,PIK3CD,TFG,PACSIN1,TUBA4A,LAMP2,VPS11,UXT,BNIP3L,KIF13A,ICMT,MCFD2,RNF19B,RAB2B,AREG,GNPTAB,ATP7B,TRAF3IP1,NOD2,F2RL1,GGA1,SEC61G,RAB23,GPSM2,SLC1A3,APBA1,FAM21C,MERTK,LMNA,ATG4A,CALR,DOPEY2,SNX18,RIMS3,ATP5H,RPL39,NECAB3,FBXO7,RANBP1,SORL1,CADPS2,PIKFYVE,SYTL3,NUP85,PPP6R1,TMED2,RIMS2,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,CALM1,ERO1A,NPC2,SRSF5,RHOB,STX3,AP1AR,SCARB2,PRKAG2,TIMM8A,HTT,ZDHHC20,WDR19,ITPR1,FAM83D,NDE1,HOOK1,NRBP1,NUP58,EHD1,KIF3C,MTM1,CCDC109B,DLGAP5,FTH1,BCL2L1,ZFYVE9,APPBP2,TNPO2,IFIT1,ARL4D,RAB27B,TBC1D10B,ATG4D,SNX8,SEC23A,SEC61B,PSRC1,COG2,FZD4,DMTN,SYNE2,VPS4B,HTATIP2,KIF1C,NUSAP1,ATP1B1,RAB38,ITPR3,ATP10D,PEX5,STX10,DDOST,AXL,RAB29,PRIMA1,RGS14,SLC25A30,HSP90B1,TAOK2,ATP9A,HABP4,ARL4C,BTN3A1,PDIA3,CTSZ,PLD2,SPDL1,IFT27,PDIA4,ANK1,PDCD10,CTSC,PPP1R10,FAM160A2,CD9,BAX,KLC3,SPRY2,ZWINT,LCA5,CASK,ZC3H11A,PIK3R1,MRS2,FURIN,VAMP3,RAB3IP,FAM109A,RGPD5,LDLRAP1,RPL12,FGFR2,RAB11FIP2,SYT7,NR4A3,ARFGAP3,SSNA1,CENPE,ARSB,ESPL1,SRSF9,EXPH5,UNC93B1,FAF2,CPT2,NDC80,ARFGEF1,UBE2Q1,KIF2C,HDAC6,PDGFB,SLC8B1,ERP29,ZFYVE16,RAB15,CTNNB1,LMAN2L,DPYSL2,ARL1,DLG1,KIF22,RAB20,RP2,CTTN,TRAM1,MYRIP,S100A13,RASGRP1,SOD1,CENPA,EZR,ARFRP1,VCP,OPTN,TRIM9,TBC1D17,WIPI1,RAB11FIP1,KPNA2,TC2N,PCSK5,PRKAA2,GRN,PEX6,CALM3,RAB6A,PGAP1,SSX2IP,RB1,TIMP1,GATA2,KIF13B,EXOC8,PRKCI,SRP54,NTN1,GAD1,KDELR1,STRADB,BTN3A2,SCRIB,ZDHHC3,NMT2,GNAS,TSC1,PVRL2,NFKBIA,CDCA5,RAB31,ZDHHC7,CTSA,LTBP2,PLD1,SHROOM2,JAK3,TOB1,DRD1,SLC25A24,UPF3B,TP53,P2RX7,MICALL2,EMP2,BCAP31,SDF4,SYTL2,TTC21B,PDGFA,SVBP,KIF14,ZDHHC12,PLCG2,ZDHHC23,BCL6,STEAP3,RPN2,LMAN1,F2R,UPF3A,CHP1,PPIF,AKT1,AP5M1,DAG1,TAPBP,ALDH5A1,PEX2,MAOA,SPTBN5,CHMP4B,SYT13,RPL22,ABCA1,COPG1,ANXA3,SORT1,TRAPPC10,CD63,SH3D19,CDCA8,AIP,VPS26A,ITGA2B,HMGXB4,ZDHHC21,M6PR,KIF5B,SNX13,MLPH,ADORA1,CDK16,LLGL2,CPLX1,ABCD1,SYK,RPGR,CAMK2G,MYO5A,HES1,SUN2,RAB3B,PRICKLE1,COL7A1,AKAP3,BBS2,SCRN2,MAP1B,SERPINA1,SCG2,ARRB1,PKD2,MCUR1,SPCS3,GEM,NDFIP1,ABCG1,SNPH |
| 2.885e-05 | -10.45 | response to chemical | biological process | GO:0042221 | 3971 | 673 | 16441 | 2455 |
TRIM24,ADD1,IL15RA,TRIM5,SLC25A13,DNAJC3,RET,FBXO2,CCNO,NRG2,IL18,CMTM6,TP73,CALM2,ZYX,PSMD1,TGFBR3,CYP2S1,SLC46A1,KLF3,DNM2,CLDN4,SEMA3G,PPP1CA,MANF,PIK3CD,TIAM1,IL10RB,TIPARP,KDELR3,PRKAR2B,LOXL2,F12,CYP4F3,ABR,PIAS3,ENPP1,PLCG1,LIMK1,ATP7B,NOD2,HDAC1,RNASEL,HSPB1,GAB1,ANXA11,SCN5A,SEC61G,CYP2J2,SOX9,MTL5,LMNA,TFAP4,RAC2,MEGF8,FLRT3,STT3B,MYDGF,NCAM1,MAPK7,NUP85,EPHX1,PAQR7,UFD1L,MAPKAPK3,STAT4,ERO1A,SHARPIN,FHL2,CALCRL,ELK1,MEST,DPYSL4,PSMA4,RHOB,CYB5A,IL1R1,NCOA3,FNTA,HTT,SEMA4D,ITPR1,DGAT2,OSMR,AURKA,B4GAT1,ALG2,ARPC2,TRPC3,NUP58,RPS6KA3,TMEM173,EGLN1,NQO1,PAPSS2,WDTC1,IL13RA1,MGST2,PRKACA,CCND1,CDH1,SP100,ACSL4,LRP11,DLG3,RASGEF1A,CDKN2D,ETV4,MX1,SEC61B,COL6A2,RIPK2,FZD4,PFKFB2,VPS4B,SYP,IRS2,ALDH3B1,CDK19,WFS1,AXL,WWTR1,ARNT,MAPK12,TNRC6C,NKX3-1,HSP90B1,TRAF2,FLOT1,ETS1,GSTP1,ICAM1,NEO1,CAPN2,CXCL16,ANK1,PDCD10,ADD3,IRAK1,CTSC,MCF2L,CST3,FDXR,BAX,TMBIM6,IGFBP2,MAPK11,HCN3,OPLAH,PLSCR1,RAPGEF2,PIK3R1,NUB1,GRIN1,AK4,ABLIM2,CNTNAP1,PITX2,BTG1,PLOD2,RAB11FIP2,NR1D2,ACVRL1,SLC35B3,NR4A3,OSER1,ITGAV,CMPK2,NUP37,OSR1,CD81,USF2,FOXA1,CYBRD1,PHC1,MYL9,AGRN,EPAS1,EPHA4,DNAJB11,F11R,ITPR2,HDAC6,PDGFB,SDC1,SPTB,CPNE2,PCNA,NUP210,RPS6KA2,CTNNB1,NPNT,SHC3,P4HB,IL6ST,PSMC2,PAPSS1,ABCA2,DUSP10,TNFRSF18,NTN4,S100A13,THRB,CITED4,NFE2L1,EZR,ERP44,PRKRA,IDH1,VCP,RHEB,DPYSL3,KCNMB4,MAP2,WIPI1,KPNA2,MYL12B,RRAGD,PRKAA2,RUNX2,LGALS3,DNAJB2,HLA-F,RASA2,PSMD7,IL18R1,CORO1B,BMP2,RB1,VASP,TIMP1,IGF1R,GATA2,PAK2,SLC30A6,AHCY,PIM1,NTN1,WNT3A,PSMA5,ABCC1,CYP26B1,DPYSL5,RGMB,STRADB,SCRIB,TCF7,PDK3,IFIT3,CDK5R1,RASGRP2,MAPKAPK2,PHLPP2,CSF1,LTBP2,PLD1,SEMA3A,IFI6,UGP2,FOXM1,TP53,P2RX7,ERBB2,RASGRP3,CYP26A1,SDF4,PDGFA,ATP6V0B,PLCG2,SRR,CDH3,OAS3,EGLN3,CTDSP2,CTH,SIRT1,PPIF,TIMP2,MBP,ERLEC1,TCEB2,AKT1,PTGER4,ACO1,MYL12A,DAG1,ATP13A2,PTGS2,DNAJC10,DUOX1,PTPRJ,IDE,ATP1A1,RBL1,PSMD3,PTK7,MAOA,XRCC3,EFNA5,IRF7,ARHGAP4,LTA4H,CMTM4,COL9A3,PINK1,CPEB4,TAB3,CTSB,GNAL,GABRG2,SELL,PSMD10,GDF15,AIP,IL22RA1,DNAJB9,NRP2,GBX2,TFAP2A,UBE2J1,IL17RA,TRIM21,HMGCL,KLF9,SYK,CAMK2G,GCNT1,DUSP1,P2RX4,RHOA,PSMB4,NR3C1,IFITM3,AMFR,PLAUR,LITAF,PPARA,GGH,BCAR1,BBS2,BCL10,CD83,TWSG1,SCG2,NAT1,FGF18,E2F1,PGRMC1,PKD2,TBC1D4,PTGES,ARHGEF9,ARHGEF4,TXN,ACVR1,SSH1,GATA3,CUL1,PSME1,PLXNA1,CCNB1,PICK1,TYMP,CYP1A1,SESN3,CTGF,STIM1,ELMO2,IL31RA,FOSB,STEAP2,PIK3CA,IRF2,ACVR1C,CASP9,AGO4,POR,AHRR,AREG,TBX1,EIF4EBP2,MAPK13,UNC5B,FGD1,DDX58,SEMA6B,KLF2,INPPL1,HLA-E,DGKQ,PRKAA1,SLC1A3,TNFRSF19,CALR,ITGA3,CYR61,VASN,CTPS1,DAPK1,CD70,TNFRSF12A,CACNA1D,SOCS5,EPB41L5,GFPT1,PRODH,MICB,CALM1,ANO6,EPHA1,KDM3A,NFIB,RASA1,FAS,MMP15,PRKAG2,MATN2,NR4A2,EFNA1,MAP3K5,IRF1,EHD1,PLA2G4A,SPRED1,SLC2A4,THRA,RPS6KA1,NDRG1,IQGAP1,RALBP1,CD274,EGR3,BCL2L1,FLT3,CYP39A1,GNB2,ZFYVE9,NOV,CCNA2,ACAP2,RALB,CDKN1B,DAB2IP,PDE4D,EPHB4,IFIT1,OSBPL7,SULT2B1,NR2C1,SEMA3B,DOCK4,DMTN,PRKCQ,SLC11A2,CBL,ITPR3,ALCAM,FZD7,CMTM7,EPHA10,FYN,DDOST,JAK1,STK26,NGFRAP1,STAT1,PPP1CB,SLC27A1,NRG1,NR3C2,CBX7,PRKAR1A,OTUD5,ARHGEF3,PLSCR4,EPS8,HERC5,GPR180,FBXO6,EFNB1,FGF19,HLA-A,RND1,OXCT1,PTEN,FUT8,CD9,ATP8B1,ERBB3,CITED2,MAP3K7,TTPA,GFI1,TRIM62,SPRY2,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,B3GNT2,SHMT1,ALDH2,ARHGEF28,PAPD7,FURIN,PARP4,YES1,FOS,GPLD1,NUCB1,RGS9,TIMP3,FGFR2,PRDX3,ABCB1,RYK,GRIN2D,GPER1,FZD5,ARSB,CPEB2,MELK,RGMA,CCNC,EMX1,CASP3,FAF2,UGT8,CACNB4,TRIM68,HTR1D,ZFYVE16,ZCCHC12,DPYSL2,DLG1,AKR1B1,TRPC1,ASH2L,MYH14,ARNT2,IL1RAP,RASGRP1,SP5,CYP1B1,SOD1,TRIM8,ASXL1,USP18,RNF165,MDK,MADD,CAB39,ADIPOR1,PPP2R5D,PSMC1,NR2C2,PCSK5,GRN,ETV5,ABCG2,ATP6V1E2,CALM3,PHLPP1,DUSP5,SPP1,CES2,CA2,PFKL,COL6A1,PRKCI,SRP54,C10orf54,HLA-C,HP1BP3,OXR1,RANBP9,EGFR,FECH,GNAS,BCAR3,TSC1,INSR,TMEM30A,NFKBIA,SH3BP4,RAB31,PITPNA,YOD1,JAK3,RARG,COL16A1,DRD1,KLF7,GAS2L1,SLC25A24,SORBS1,IL15,PSME2,SLC2A8,PDIA5,SOD2,COL18A1,IL27RA,ARHGEF16,SS18,ARTN,CYP4F11,KIF14,SMO,RPN2,TWIST1,GOT1,NFKB2,PDIA6,LOXL1,F2R,HSPA2,FRS3,BAG4,PTPRU,ERBB2IP,DUSP4,CD40,CASP4,ARHGAP35,SOCS3,STAT6,SPTBN5,CYP2U1,PLXND1,LIFR,ABCA1,GCLM,ANXA3,SORT1,ARHGEF11,ARHGEF7,JKAMP,SERPINB9,LRP4,TGFBR1,COL4A5,AES,ITGA2B,HDAC9,KIF5B,IL17RB,ADRBK1,BMP7,TOX2,IQGAP3,MYO5A,ADAM17,WNT10B,NR4A1,GCLC,RGCC,RUNX3,LEPR,CTSL,HLA-B,MARC1,DHRS2,CTSV,UBE2D2,HOXB13,ATP6V1C1,PLOD3,L1CAM,AHR,ABCG1,NGEF |
| 2.888e-05 | -10.45 | cytoskeletal part | cellular component | GO:0044430 | 1403 | 259 | 17570 | 2579 |
ADD1,KLC2,XIAP,CNTROB,SYTL4,CCNB1,FAM101B,KIF26A,PHF1,CALM2,ZYX,STIM1,DNAH6,DNM2,TUBG1,HYLS1,ODF2L,TUBA4A,SPEF2,KIFC2,SNTB2,DSTN,UXT,PRKAR2B,KIF13A,AURKB,CCNF,SLC25A5,MYOM1,LCP1,MID1IP1,CAMK2N2,DNM1L,PLK2,TRAF3IP1,MYLK,FAM110C,MAP3K11,TMOD2,HSPB1,TRAF5,ANXA11,KIF23,TXNDC9,LMNA,FLII,RAC2,FRY,NEK2,SLAIN2,NUP85,TTLL1,DNAI1,KIF20A,CEP89,B9D2,CALM1,PLS1,KIF20B,ILK,FNTA,PLEKHH2,HTT,AGBL5,FAM83D,AURKA,MDH1,NDE1,ARPC2,CFAP20,HOOK1,RUSC1,KIF3C,CEP70,DLGAP5,TUBB4B,RPS6KA1,ACTR8,IQGAP1,NDRG1,PKP2,BCL2L1,PRKACA,APC2,MNS1,APPBP2,SCNN1A,CDH1,PDE4D,ZNF365,SNX10,FLOT2,MYO5B,CAMSAP3,PSRC1,CAPN6,DMTN,SEPT6,VPS4B,KIF1C,NUSAP1,GABARAPL1,NIN,CEP162,FYN,SHROOM3,STK26,TRIOBP,RGS14,GEN1,COBL,TTC8,MZT1,CKAP2,RASSF7,FLOT1,NES,SPDL1,DNAH3,IFT27,CKAP5,CAPN2,PHF7,CENPJ,CALD1,TUBGCP6,PRC1,KLC3,ERCC2,SPRY2,LCA5,FMN1,TACC1,PLEKHA7,PARP4,RAB3IP,YES1,AIF1L,SKA1,KIF11,DCTN6,LDLRAP1,SSNA1,GPER1,CENPE,WDR62,ESPL1,MYL9,NDRG2,KIF2C,HDAC6,MAP1LC3B,SPTB,RPS6KA2,PCNA,CTNNB1,CNTRL,DPYSL2,DDHD2,CEP78,ABCA2,DLG1,CAPG,KIF22,CTTN,MYH14,RP2,CCDC38,KRT80,PLK1,PCGF5,FOPNL,STAU2,CKAP2L,EZR,ANLN,CDK1,DPYSL3,DZIP1L,PLEKHG6,NEIL1,MAP2,MYL12B,PIFO,LASP1,BMF,PPP1R12A,CALM3,RACGAP1,SSX2IP,MYO5C,CORO1B,RB1,KIF13B,TBCD,KNTC1,LRIF1,MPHOSPH9,C9orf9,TPGS2,KBTBD8,NUBP1,RANBP9,MAPKAPK2,TSC1,KIF12,CCNB2,SHROOM2,GAS2L1,DYNLRB1,SORBS1,UPF3B,NF2,ZMYND10,MICALL2,STIL,LRRC45,SS18,TACC2,KIF14,PLK4,ESPN,AKT1,CDC20,CCSAP,MYL12A,BFSP1,SPTBN5,SGOL1,REEP4,MAD2L1BP,FBLIM1,POC1B,ERCC6L,CDCA8,SAC3D1,TOP2A,CCDC92,KIF5B,TBC1D31,CEP97,MZT2A,LLGL2,TFAP2A,CLIP2,RPGR,MYO5A,ASPM,SYBU,RGCC,BBS2,BCL10,MAP1B,PKD2,PPP2R3C,GEM,CEP41,SNPH,DIS3L |
| 2.915e-05 | -10.44 | BAE_BRCA1_TARGETS_UP | MSigDB lists | BAE_BRCA1_TARGETS_UP | 70 | 24 | 17758 | 2588 |
LAMP2,NEK4,GAA,LGALS3,EPAS1,DRAP1,SAT1,NDUFA4,COL4A5,BCL7B,GTF2A2,PRDX4,NOV,BTG1,KCNK1,STAT6,BMP7,SPINT2,RYK,SORL1,MTMR11,TRAM1,SEPHS1,ABCG1 |
| 2.915e-05 | -10.44 | MARTINEZ_RB1_AND_TP53_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_UP | 579 | 120 | 17758 | 2588 |
SLC2A4,SORBS1,ADD1,EPAS1,NDRG1,PNPLA2,SLC25A13,PTTG1,TP53,PLAC1,OSR2,DDR1,EMP2,BCAP31,SH3KBP1,IER3,PDGFA,WEE1,NOV,TGFBR3,IL6ST,KLF3,DNM2,CTTN,MARCH2,EGLN3,LMAN1,SULT2B1,CTDSP2,TUBA4A,MYO5B,CPD,TMCC2,BAG4,CAPN6,PBK,ACBD3,ACO1,SLC11A2,GLO1,RAB2B,LCP1,DPYSL3,PTGS2,IDE,JAK1,ACYP1,HOXA9,BMP1,CHPT1,SLC25A30,RECQL,LASP1,SORT1,INPPL1,PINK1,MRC2,SCOC,KLHL13,DAP,MAN1A2,CTSB,ERI2,RACGAP1,COL4A5,RBP7,FAM21C,FBLN1,HOXB2,LGALS3BP,SIRPA,SGPL1,ADD3,DNPEP,FUT2,TIMP1,CYR61,DRAM1,BRAT1,AK3,ACAD8,FAH,DUSP1,QSOX1,FADS2,PDGFC,KIF20A,NR3C1,ZC3H11A,NR4A1,LITAF,FHL2,TCF7,BCL2L13,AIF1L,TP53INP2,KIF11,FOS,NUBP1,RANBP9,EGFR,MAP1B,GNAS,FECH,FUCA1,PITX2,PTPRF,FNTA,DGCR2,TWSG1,FGFR2,RAB31,DCUN1D1,PLD1,ITGAV,SERPINB1,AHR,HIPK3,XDH,RAD21 |
| 2.951e-05 | -10.43 | BROWNE_HCMV_INFECTION_48HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_48HR_UP | 174 | 46 | 17758 | 2588 |
ANXA3,COL9A3,LRP4,RET,HMGN3,ITPR2,IL18R1,EPM2A,IER3,CYP1A1,PLCG2,RUNDC3B,MSH2,IGFBP2,USP1,ZNF365,CPE,IL10RB,HSPA2,CTH,CKS2,CD55,CELSR2,MRS2,EZR,CALCRL,GGH,RUNX3,PDK3,CCNF,SLC25A5,MAN2A2,FUCA1,HSF4,ONECUT1,PRPS2,ITPR1,PPM1H,CCDC69,TLE1,GEM,LIFR,PTGES,COBL,GAB1,ABCG1 |
| 2.959e-05 | -10.43 | TIEN_INTESTINE_PROBIOTICS_24HR_UP | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_UP | 539 | 113 | 17758 | 2588 |
SPC25,DLGAP5,LGR4,FOXM1,ST14,CAST,SLC25A13,PTTG1,NDC80,ETNK1,MORC4,TGOLN2,PLXNA1,MGST2,SNN,CCNB1,OAT,CENPN,CMTM6,CCND1,ZFYVE16,APOBEC3B,PCNA,PSMD1,CCNA2,ENTPD4,LMAN2L,KIF14,SIVA1,ATP13A3,TUBG1,TAX1BP3,RP2,GM2A,CKS2,METAP2,PLK1,PPIF,CENPA,HTATIP2,NUSAP1,ARHGDIB,ATP1B1,ICMT,H2AFV,PDHX,DAG1,FASTKD1,SLC25A4,ACYP1,SLC9A6,IARS2,MRPS28,PSMC1,ISOC1,NXT2,RECQL,PACSIN2,FARP1,MPZL1,HJURP,CENPI,ARL4C,ERI2,KIF23,ASAH1,RACGAP1,HMGN3,NTAN1,SAC3D1,GNS,AIM1L,FAM111A,TNS3,CALD1,PRC1,SGK1,BUB1,ALDH7A1,TAGLN2,NPTN,FAIM,TPCN1,NUP85,MSH6,SMC4,HMMR,ZWINT,DCAF6,MMD,PRSS23,KIF20A,RAPGEF2,MRS2,VAMP3,FBXO9,GGH,UBAC1,SRSF5,KIF11,FRMD4B,ENDOD1,DGCR2,DCK,AMMECR1,DBI,TCEAL4,PPM1H,AURKA,TMEM14A,ESPL1,CSRP2,DOCK9 |
| 2.960e-05 | -10.43 | WANG_CISPLATIN_RESPONSE_AND_XPC_DN | MSigDB lists | WANG_CISPLATIN_RESPONSE_AND_XPC_DN | 220 | 55 | 17758 | 2588 |
CASP3,ACVR1,DYRK3,UGP2,TRIP10,NUAK1,TSC22D3,BTN3A1,EGR3,CDIPT,TEAD3,CAPN2,CD46,RAC2,ZFX,INPP5E,ADD3,KHNYN,SP100,EFR3A,GALNS,CAPG,BCL6,PRKG1,CNPY3,EBAG9,CYP1B1,TGIF1,TESK1,CTNNAL1,HSPA12A,PARP4,CDA,SNAPC2,SESN1,STEAP1,CASP4,CNTNAP1,IL1R1,MAN2A2,TSC1,NT5C2,BTG1,FNTA,KIAA0141,CSF1,STAT1,CSTF2,KLF5,NRG1,SSNA1,ATP6V1C1,SLC31A2,HIPK3,CYBRD1 |
| 2.968e-05 | -10.42 | plasma membrane organization | biological process | GO:0007009 | 205 | 53 | 16441 | 2455 |
PLSCR4,PACSIN2,AGRN,TSPAN15,NDRG1,FLOT1,PKP2,P2RX7,MPP5,F11R,ANO9,SNX9,EMP2,SPTB,TSPAN17,RAB15,ANK1,CDH1,PTEN,A4GALT,DLG1,ZDHHC23,PLEKHF1,PACSIN1,ANO4,FLOT2,TMED2,MYO5A,TSPAN33,XKR8,GCC2,BAG4,SOD1,KCNIP3,RAB3B,PLSCR1,AKT1,CRB3,RAPGEF2,ANO6,VAMP3,EZR,KIF13A,ARFRP1,ATP1B1,BBS2,OPTN,FA2H,FAT4,SYT7,RAB31,DYSF,ATP1B3 |
| 2.983e-05 | -10.42 | Interleukin-2 signaling | REACTOME pathways | R-HSA-451927 | 245 | 61 | 8202 | 1235 |
SPRED1,INPPL1,PSME2,IQGAP1,RASA2,INPP5D,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,DUSP5,FGF19,SPTB,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,PIK3CD,ERBB3,NCAM1,RASGEF1A,SYK,RASGRP1,CAMK2G,PSMA5,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,DUSP4,PSMA4,EGFR,RASA1,IRS2,FYN,JAK1,PPP2R5A,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3,PPP2R5D,PSMC1 |
| 3.041e-05 | -10.40 | small molecule binding | molecular function | GO:0036094 | 2600 | 455 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,OSBPL3,ALDH1A3,SLC46A1,ATP13A3,PIK3CA,AOX1,DNM2,TUBG1,CRY2,PIK3CD,ACOX2,TUBA4A,NEK4,NWD1,VPS11,SMARCA2,LOC81691,KIFC2,ACVR1C,PBK,HSPA12A,CDA,PRKAR2B,KIF13A,PIF1,AURKB,TP53I3,POR,RAB2B,ARF4,ULK2,ENPP1,RBM47,DNM1L,PLK2,LIMK1,CELF5,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,DHTKD1,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,AKAP17A,KIF23,SLC1A3,MERTK,BMP2K,RAVER2,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,CNGA1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,PRODH,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,NPC2,EPHA1,SRSF5,ATP8B3,PKM,ILK,PCTP,GNA11,RHOB,STX3,PDE11A,STK17A,DHX32,DGKH,NT5C2,PRKAG2,CSNK1G1,DCK,AURKA,MDH1,STK39,CDK18,MAP3K5,IFIH1,TRPC3,NRBP1,RPS6KA3,TMEM173,XDH,EGLN1,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,AIFM2,PRKACA,FLT3,DDR1,MOCS1,RBM23,TRANK1,RALB,FICD,PDE4D,ACSL4,EPHB4,OSBPL7,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,AGPS,SEPT6,PANK1,VPS4B,TEP1,KIF1C,SYP,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ITPR3,ATP10D,NIN,EPHA10,OSBPL2,FYN,JAK1,ACAD10,CDK19,STK26,AXL,KIAA1804,SLC27A1,RAB29,PDXK,MLKL,SLC27A3,MAPK12,PRKAR1A,GALK1,TNRC6C,TAOK2,HSP90B1,RBM24,ATP9A,ESRP1,ARL4C,PKN1,SPR,DNAH3,IFT27,RND1,DIRAS3,SLC27A6,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,TTPA,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,SHMT1,RAPGEF2,GRIN1,UBE2A,AK4,PIM3,YES1,KIF11,TXK,ACADSB,PLOD2,FGFR2,ACVRL1,ABCB1,RYK,CSTF2,RABL6,CENPE,LRRK1,CMPK2,CPEB2,SRSF9,MELK,ESYT2,TNK1,NMRK1,AGRN,ST13,CRYM,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,CDIPT,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,LMAN2L,PSMC2,PAPSS1,PASK,ABCA2,TRPC1,KIF22,RAB20,RP2,MYH14,DDX59,RASGRP1,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,IDH1,CDK1,ADRBK2,STK17B,VCP,TCN2,RHEB,SEC14L2,PI4K2B,P4HA2,IARS2,PIK3C2B,RBM43,PSMC1,RRAGD,PRKAA2,RUNX2,LMTK3,PEX6,BVES,ABCG2,RAB6A,TEC,DHRS3,MYO5C,DAZAP1,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,AHCY,PIM1,ACAD8,ABCC1,CYP26B1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,P4HA3,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,CTBP1,PROM2,UGP2,UPF3B,SLC2A8,P3H2,ABCG4,DGKA,TP53,ERBB2,P2RX7,MRAS,CYP26A1,SYTL2,CDK14,KIF14,FABP6,SRR,PLK4,GYS1,GOT1,OAS3,LMAN1,EGLN3,SCYL3,HSPA2,UPF3A,SEPHS1,MAP3K3,SIRT1,SOAT1,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,DUOX1,IDE,ATP1A1,STK38,PTK7,PTBP3,MAOA,XRCC3,RCAN2,ANXA9,AIFM3,ABCA1,PINK1,DYRK3,TOR4A,CPEB4,SHPRH,CIT,GNE,GNAL,ERCC6L,TGFBR1,CRABP2,TRIB2,RBP7,M6PR,TMEM63A,KIF5B,TOP2A,ADORA1,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,HMGCL,ABCD1,HSPA13,SYK,CAMK2G,ATP2B1,MYO5A,RBMS2,P2RX4,RAB3B,RHOA,GCLC,OGDHL,NADK2,RUNX3,SPAG1,DGKE,DDX23,FUCA1,DDAH1,SWAP70,RND3,HNRNPH2,RAP2C,UBE2D2,ACADM,GEM,PLOD3,UBE2C,L1CAM,HIPK3,ZBTB33,ABCG1 |
| 3.042e-05 | -10.40 | regulation of cellular component biogenesis | biological process | GO:0044087 | 697 | 143 | 16441 | 2455 |
SSH1,ADD1,AGRN,ARFGEF1,HDAC6,SNX9,SDC1,SPTB,CTNNB1,CTGF,PSMC2,MITF,DLG1,CAPG,DNM2,TACSTD2,CTTN,PLK1,VPS11,EZR,LDB2,VCP,LCP1,DPYSL3,TRIM9,TBC1D17,DNM1L,PLK2,LIMK1,TRAF3IP1,FAM110C,TMOD2,PIEZO1,ARF6,RAP1GAP,F2RL1,PSMC1,BMF,HJURP,TBC1D1,DNAJB2,SOX9,PRKAA1,SORBS3,NCKAP1,RB1,RAC2,VASP,CYR61,FLRT3,TBCD,FNIP1,SORL1,SLAIN2,PIKFYVE,EPB41L5,PIP4K2C,EPHA1,RASA1,FAS,NUDT16,TSC1,HTT,ARAP1,SAMD8,PLD1,ARPC2,COL16A1,ADAMTS16,NF2,THRA,TP53,P2RX7,PKP2,PATL2,PRKACA,MNS1,EPS8L2,RALB,KIF14,LMO4,PLK4,CDKN1B,TWIST1,ESPN,DAB2IP,HSPA2,TBC1D10B,SSH3,BAG4,PSRC1,DMTN,CLSTN1,VPS4B,PTGER4,PRKCQ,DAG1,IDE,PTPRJ,PEX5,BHLHB9,CORO1C,TRIOBP,SPTBN5,EFNA5,KLF5,CHMP4B,COBL,FBLIM1,PINK1,SDC4,BIK,EPS8,FLOT1,TGFBR1,SRPX2,SIX4,ADGRB2,ICAM1,CTNNBIP1,PTEN,CENPJ,BMP7,TUBGCP6,GTF2F2,BAX,ATP8B1,MAP3K7,CNOT6L,FARP2,RHOA,WNT10B,FMN1,RAPGEF2,PIK3R1,GRIN1,RGCC,ARHGAP24,CNOT2,SWAP70,ACVRL1,FZD5,AHR |
| 3.088e-05 | -10.39 | Mitotic Prometaphase | REACTOME pathways | R-HSA-68877 | 108 | 33 | 8202 | 1235 |
SPC25,CENPI,NDC80,ERCC6L,CDCA8,NUF2,KIF2C,CCNB1,SPDL1,CENPN,CKAP5,BUB1,KNTC1,NUP85,SMC4,PLK1,CENPA,ZWINT,CENPC,B9D2,CDC20,AURKB,SKA1,CDK1,PPP2R5A,CDCA5,CENPE,NDE1,NUP37,SGOL1,CCNB2,PPP2R5D,RAD21 |
| 3.107e-05 | -10.38 | cellular polysaccharide metabolic process | biological process | GO:0044264 | 73 | 25 | 16441 | 2455 |
PGM1,GAA,B3GNT2,PPP1R2,UGP2,AKT1,CALM1,CALM3,PYGL,MGAM,NANS,EXT2,EPM2A,PER2,CALM2,PRKAG2,IL6ST,CSGALNACT1,GYS1,PGM2L1,PPP1CB,B4GAT1,PPP1CA,PHKA2,PHKG2 |
| 3.150e-05 | -10.37 | Cyclin_C-dom | interpro domains | IPR004367 | 17 | 10 | 18293 | 2672 |
CCNE2,CCND1,CCNA2,CCNB3,CCNO,CCNJL,CCNL1,CCNB1,CCNF,CCNB2 |
| 3.166e-05 | -10.36 | EF_hand_dom | interpro domains | IPR002048 | 220 | 55 | 18293 | 2672 |
MYL9,SLC25A24,REPS2,CAPN12,S100A11,SLC25A13,RHBDL3,CALB2,DGKA,CALM3,EFHD2,RASGRP3,NUCB2,S100A2,REPS1,HPCAL4,PPP2R3A,SDF4,NCS1,PLS3,CAPN2,RCN1,CALM2,CABP1,NECAB3,DGKG,RASGRP1,S100A6,CHP1,GCA,KCNIP3,TBC1D8B,S100A4,CALM1,CAPNS1,PLS1,MCFD2,AIF1L,MYL12A,LCP1,RASGRP2,NIN,DUOX1,PLCH1,NUCB1,PLCG1,SWAP70,GNPTAB,CGREF1,NKD1,S100A5,EFCAB14,PKD2,CAPN1,EHD1 |
| 3.167e-05 | -10.36 | ELVIDGE_HIF1A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_TARGETS_DN | 88 | 28 | 17758 | 2588 |
OLFML2A,QSOX1,PGM1,ENO2,ZNF395,NR3C1,S100A4,NDRG1,BNIP3L,AK4,LOXL2,PDGFB,DPYSL4,FOS,PGAP1,EGFR,FYN,CYP1A1,SRPX,P4HA2,GYS1,EGLN3,CITED2,LOXL1,MAFF,CSRP2,RRAGD,EGLN1 |
| 3.186e-05 | -10.35 | lysosomal lumen | cellular component | GO:0043202 | 83 | 27 | 17570 | 2579 |
LAMP2,GAA,AGRN,HSPG2,GUSB,CTSB,HEXB,SDC4,ASAH1,SDC1,TCN2,ATP13A2,FUCA1,CTSL,GNS,SCARB2,HPSE,GPC3,CTSV,GALNS,GLB1,CTSA,GLA,CTSD,LGMN,ARSB,GM2A |
| 3.207e-05 | -10.35 | stress-activated protein kinase signaling cascade | biological process | GO:0031098 | 156 | 43 | 16441 | 2455 |
TAOK2,TAB3,RPS6KA1,CCM2,CUL1,PKN1,TNFRSF19,PAK6,RPS6KA2,IRAK1,PAK2,MAP3K9,AKR1B1,DUSP10,DAB2IP,MDFIC,MAPK11,MAP3K7,MAPK7,SYK,MDFI,NEK4,RHOA,RIPK2,MAPKAPK3,PTGER4,STRADB,ELK1,DUSP4,FOS,MAP3K6,MAPK8IP1,MAPKAPK2,STK26,SH2D3C,KIAA1804,MAP3K11,NOD2,STK39,MAP3K5,GAB1,PPP2R5D,RPS6KA3 |
| 3.219e-05 | -10.34 | MEL18_DN.V1_UP | MSigDB lists | MEL18_DN.V1_UP | 135 | 38 | 17758 | 2588 |
AGRN,ARL4C,TAP1,PLXNA1,SRPX2,TNFSF9,CHST2,FZD6,NRP2,CCND1,SPP1,TGFBR3,ITGA3,ITGB8,SLC16A6,FJX1,TMEM51,STEAP3,SUN2,MICB,PLAUR,C3orf52,FURIN,COL7A1,ITPR3,LHFPL2,LCP1,CRISPLD2,ATP13A2,CD83,MMP15,SLCO4A1,COL13A1,CSF1,LRIG1,SLC2A6,PIEZO1,COL16A1 |
| 3.225e-05 | -10.34 | WEIGEL_OXIDATIVE_STRESS_RESPONSE | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_RESPONSE | 34 | 15 | 17758 | 2588 |
GNAS,CASK,CCNA2,ADORA1,NF2,XIAP,DAPK1,BAX,CDH3,CAPNS1,IGFBP2,HMGA1,FOS,NFIX,IER3 |
| 3.234e-05 | -10.34 | cell adhesion | biological process | GO:0007155 | 1036 | 201 | 16441 | 2455 |
MYL9,BCAM,KIAA1462,EPHA4,RET,GATA3,F11R,EPDR1,LYPD5,EPCAM,ZYX,MUC4,CTNNB1,CTGF,NPNT,ELMO2,DLG1,CLDN4,PIK3CD,TINAGL1,CTTN,TLN2,TIAM1,SMAGP,CYP1B1,SGCE,CELSR2,TNIP1,EZR,LOXL2,LCP1,COL12A1,HPSE,CTNND1,TMEM8B,ARF6,HSPB1,F2RL1,CD99,RUNX2,INPPL1,NUAK1,THEMIS2,BVES,ITGA6,HLA-E,SOX9,SORBS3,CNTNAP2,APBA1,MERTK,IL18R1,SSX2IP,SPP1,RAC2,ITGA3,LRRN2,CYR61,LYPD3,CD22,ICAM5,FLRT3,KIF13B,COL6A1,CTPS1,TNFRSF12A,NPTN,NCAM1,TMEM8A,NTN1,WNT3A,SNED1,EPB41L5,PODXL2,PCDH1,RGMB,MICB,DCHS1,SCRIB,VEZT,EPHA1,CYFIP2,ILK,ANTXR1,RHOB,EGFR,CDK5R1,FAS,GNAS,PTPRF,TSC1,SCARB2,SEMA4D,PVRL2,COL13A1,PLPP3,ITGA7,CGREF1,PCDH19,EGFL7,EFNA1,AKIP1,COL16A1,IRF1,SORBS1,GRHL2,LFNG,IL15,CERCAM,TP53,P2RX7,TESK2,PKP2,COL18A1,MICALL2,FLT3,EMP2,DDR1,NOV,MUC16,CDH1,SRPX,KIF14,CDH3,EPHB4,FLOT2,CAMSAP3,COL6A2,RIPK2,FZD4,PTPRU,PTGER4,CLSTN1,ATP1B1,ERBB2IP,ALCAM,MYL12A,DAG1,FZD7,FYN,DDOST,AXL,STAT6,PTK7,ANXA9,RPL22,FBLIM1,TAOK2,CDH22,CD63,ADGRG1,HAPLN3,ARHGEF7,GNE,BTN3A1,CBLL1,SELL,JAG2,EFNB1,SRPX2,LGALS3BP,ICAM1,NRP2,SIRPA,ITGA2B,NEO1,ITGB8,IGSF9,BMP7,BAX,CD9,ARVCF,ADAM15,RAG1,SYK,FARP2,GCNT1,PVRL4,HES1,ADAM17,RHOA,CASK,FBLN5,CTNNAL1,RC3H2,VAMP3,PLEKHA7,COL7A1,FNDC3A,BCAR1,TXK,CNTNAP1,CD8A,FAT4,DGCR2,RND3,ITGAV,ICOSLG,FZD5,L1CAM,CD33 |
| 3.260e-05 | -10.33 | MODULE_100 | MSigDB lists | MODULE_100 | 523 | 110 | 17758 | 2588 |
TRIM2,PAX6,EPAS1,CRYM,THRA,EPHA4,TMX4,CACNA2D2,C5orf30,NRG2,BAIAP3,PLA2G16,APC2,PHLDA1,PHYHIP,SRPX,TACC2,CABP1,LMO4,ALDH1A3,RGS5,ARNT2,IFIT1,BTBD3,CPE,HSPA2,TMCC2,SGCE,MBP,COL6A2,CBX6,KLK6,ROR1,ATP1B1,LDB2,ALCAM,PLEKHB1,FZD7,DPYSL3,MDK,TRIM9,GPRC5B,MAP2,KCNK1,MYLK,TLE1,MAOA,RCAN2,SERPINI1,ITPKA,APBA2,NRGN,BIN1,WASF3,COL9A3,CDH22,IGFBP6,ENO2,ATP9A,ITGA6,DNAJB2,CALB2,SOX9,GABRG2,SLC1A3,CNTNAP2,SEPP1,TSPAN7,DUSP5,PARM1,RND1,NEO1,ELF3,DIRAS3,SPP1,CA2,NECAB3,GPC3,RIMS3,IGFBP2,ALDH7A1,HSPA13,NCAM1,GAD1,RIMS2,EPHX1,FADS2,NR4A1,GRIN1,DPYSL4,FOS,RHOB,TIMP3,SERPINA1,DGCR2,SCG2,FGFR2,RND3,ITGA7,NAB2,ITPR1,TCEAL4,RAB31,STK39,CDK18,L1CAM,CSRP2,PKIA,SNPH,ARHGEF4 |
| 3.260e-05 | -10.33 | KIM_ALL_DISORDERS_CALB1_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_CALB1_CORR_UP | 523 | 110 | 17758 | 2588 |
DOC2A,KIF3C,TUBB4B,CRYM,TMX4,CUL1,BLCAP,EGR3,MORF4L2,OAT,PJA2,SLC20A1,ERP29,MAP1LC3B,APLP2,ATP6V0B,PSMD1,KIAA1107,EFR3A,DDHD2,REEP1,AKR1B1,ATRNL1,GOT1,TECR,DLG3,BTBD3,TIAM1,ZNF365,GPX4,TUBA4A,DOCK4,SEC23A,RFK,AKT1,DSTN,STAU2,HSPA12A,RNF11,CLSTN1,NFE2L1,BNIP3L,PRKAR2B,ATP1B1,LDB2,ZFAND5,PDHX,ABR,OPTN,MAN2A2,SLC25A4,DDOST,KCNK1,GDE1,PLK2,SLC9A6,MADD,RCAN2,SERPINI1,NRGN,PSMC1,PRKAR1A,HSP90B1,PINK1,PPP1R12A,ENO2,PSMD7,GABRG2,NCKAP1,TRIB2,COX7A2,SLC25A36,B3GALNT1,GNB5,ICAM5,PRKCI,SORL1,H2AFY,AHCY,HSPA13,NPTN,TMED2,CAMK2G,ATP2B1,SOCS5,MOB4,PSMB4,UBE2A,FHL2,FBXO9,CYFIP2,PSMA4,RASA1,GNAS,GABRD,SCG2,ITPR1,SPINT2,PGRMC1,PPM1H,SPAG7,MDH1,FHL1,ATP6V1C1,CTBP1,ARHGEF9,TOB1,RUSC1,ACOT7,RAD21 |
| 3.290e-05 | -10.32 | CHANG_CORE_SERUM_RESPONSE_DN | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_DN | 195 | 50 | 17758 | 2588 |
FAM171B,HECA,ARHGEF3,ARMCX3,CDKN1C,PARP14,ZCCHC24,PYROXD2,CD82,HABP4,SOD2,C1orf198,FAM198B,VASH1,ZNF219,SLC25A36,CD46,ADD3,TRANK1,SNX18,METTL7A,DPYSL2,MEGF8,IL6ST,CST3,BCL6,ANKRD12,CRTAP,OLFML2A,FADS2,MBP,TIMP2,PTPRU,KIAA1109,H2AFV,SESN1,POR,EGFR,GABARAPL1,CNTNAP1,IL1R1,NCOA3,CTNS,C19orf66,RAB11FIP2,CSF1,SLC27A1,RNF146,ANXA11,CYBRD1 |
| 3.293e-05 | -10.32 | germ_cell_tumour | COSMIC cancer mutations | germ_cell_tumour | 900 | 174 | 17775 | 2585 |
LTBP1,TNK1,ACVR1,TMEM41B,CAMKK1,EPHA4,RET,CAMK1D,PAK6,DAPK2,WEE1,RPS6KA2,CTNNB1,CDKL5,PIK3CA,NEB,STK35,PLK1,NEK4,MARK1,ACVR1C,PBK,PRKAR2B,ROR1,AURKB,IDH1,ADRBK2,STK17B,ABR,ULK2,PLCG1,MFAP3L,PLK2,LIMK1,MYLK,MAP3K11,BMP1,MAPK13,RNASEL,SPRY4,PRKAA2,INPPL1,CDK17,DHPS,PRKAA1,ADCK5,ISYNA1,MERTK,PDXDC1,BMP2K,IGF1R,KIF13B,NEK2,MSH2,DAPK1,PRKCI,PRKG1,MAP3K9,ADCK2,FNIP1,ALPK1,PIM1,MAPK7,MYLIP,KCTD3,PHKG2,ABCC1,ADCK3,TESK1,DCHS1,STRADB,WHSC1,EIF2AK1,KIF20B,PDK3,PDIK1L,RANBP9,ZDHHC3,EGFR,STK17A,GNAS,MAPKAPK2,INSR,ALPK3,AURKA,CABIN1,CDK18,MAP3K5,JAK3,NRBP1,RPS6KA3,DMPK,SLC25A24,TCF25,TRIP10,RPS6KA1,TP53,TESK2,ERBB2,RHPN2,GRK6,PRKACA,FLT3,DDR1,CDK14,RCN1,SP100,PLK4,EPHB4,SCYL3,MAP3K3,RIPK2,AKT1,PRKCQ,PKMYT1,CBL,MAP3K6,EPHA10,DUOX1,FYN,PTPRJ,JAK1,CDK19,AXL,STK38,PTK7,KIAA1804,MLKL,FAM134B,MAPK12,PINK1,DYRK3,TAOK2,TGFBR1,PKN1,TRIB2,DSE,KCNC4,SNTA1,TMEM87B,ADRBK1,IRAK1,LLGL2,PTEN,CDK16,TUBGCP6,SGK3,CD9,H2AFY,SGK1,MAPK11,BUB1,ERBB3,MAP3K7,SYK,CAMK2G,MYO5A,CASK,ASPM,YES1,BSDC1,ABLIM2,MAP1B,TXK,FAT4,FGFR2,ACVRL1,PRCP,NEIL3,RIN3,WDR91,HIPK3,MELK,GOLGB1 |
| 3.323e-05 | -10.31 | IRS-mediated signalling | REACTOME pathways | R-HSA-112399 | 277 | 67 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,DUSP4,RHEB,IRS2,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,CAB39,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,CALM3,PSMD10,FGF19,DUSP5,ITGA2B,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,PSMA4,EGFR,RASA1,TSC1,PRKAG2,FGFR2,FGF18,ARRB1,GRIN2D,JAK3 |
| 3.341e-05 | -10.31 | GSE17721_0.5H_VS_4H_CPG_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_4H_CPG_BMDM_DN | 190 | 49 | 17758 | 2588 |
ARHGEF3,ENO2,CPEB4,IL15,TBC1D1,PPFIBP2,TAP1,IL18,MPP5,F11R,B4GALT4,REPS1,ICAM1,NRP2,MAGOHB,RPS6KA2,XYLT2,LMO4,ECE1,CACNA1D,TFG,GFI1,SGCB,MOB4,ENPP4,GCA,ADAM17,RFK,LAP3,BCL9,SYNE2,CALCRL,RAB3IP,FNDC3A,ASB13,RNF19B,ALCAM,MAPKAPK2,ETS2,C19orf66,RBL1,NAT1,CSF1,MYLK,ITGAV,PTGES,ABCA1,E2F8,RRAGD |
| 3.341e-05 | -10.31 | GSE30083_SP3_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP3_VS_SP4_THYMOCYTE_DN | 190 | 49 | 17758 | 2588 |
GRN,FAF2,TTC39B,UBASH3B,GNE,SDC4,TEX2,TRMT2B,DSE,NUCB2,FAM101B,FAM167A,IL18R1,LGALS3BP,CCND1,RCN1,INPP5E,FAM46A,CDH1,SGK1,TMEM8A,SNX10,SCYL3,SPRY2,GM2A,EPHX1,MMD,ADCK3,SNTB2,STAT4,CORO2A,SYNE2,LITAF,ALCAM,ATP10D,RHOB,DHDH,HLA-B,BANK1,LDLRAP1,HPSE,FAAH,TDRD7,IRF7,HS3ST3B1,GEM,MAP3K5,TRAF5,XDH |
| 3.354e-05 | -10.30 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | 377 | 84 | 17758 | 2588 |
LMO7,FAM171B,TRIM2,UGT8,ST13,IL15,TRIM5,IQGAP1,DNAJC3,EPHA4,RET,ETNK1,C5orf30,CD274,LACTB2,SESN3,ANKRD12,IFIT1,TFG,FAR1,ENPP4,TMTC1,MCTP1,USP18,C3orf52,PRKAR2B,GALNT7,DNAJB14,ALCAM,SFXN1,PTGS2,POPDC3,HOXA9,KLF5,SERPINI1,LIFR,TC2N,ANXA3,HSP90B1,CPEB4,KLHL13,MACC1,ARHGEF7,MCTP2,ASB9,HERC5,GDF15,TNFRSF19,ANO1,BMP2K,PARM1,SLC25A36,FOXP2,TOP2A,B3GALNT1,WDFY1,USP1,AK3,NCEH1,FAR2,FAIM,SLC12A2,RIMS2,WDR72,ASPM,LPGAT1,OXR1,SYBU,EIF5A2,PDE5A,BLVRA,MEST,IFIT3,G2E3,NR1D2,TWSG1,DHRS2,MATN2,DCUN1D1,NETO2,SOX8,CMPK2,FOXA1,USP16 |
| 3.359e-05 | -10.30 | protein homodimerization activity | molecular function | GO:0042803 | 707 | 144 | 16491 | 2452 |
ACVR1,ADD1,GRIK2,TRIM5,CRYM,HEXB,TAP1,SNX9,PDGFB,ERP29,SLC8B1,BARD1,SLC9A7,TFAP2E,HSF2,IL6ST,CABP1,ALDH1A3,PTPRE,S100A13,APOBEC3G,SMAGP,RASGRP1,FGFR1OP2,OLFML2A,SOD1,TRIM8,CDA,BNIP3L,CR2,CCBL2,PRKRA,IDH1,MYOM1,TP53I3,PLEKHB1,TRIM9,ENPP1,DNM1L,TBX1,PPP2R4,MAP3K11,GLA,RAP1GAP,E2F8,ABCG2,PSMD7,ANO1,MECOM,TFAP4,BHLHE41,FLRT3,MSH2,MAP3K9,CCDC88A,ANO6,PYGL,EIF2AK1,KIF20B,NUDT16,PVRL2,DCK,CSF1,PRPS2,DGAT2,S100A5,NR4A2,MAP3K5,CBX5,NRBP1,CTBP1,TMEM173,XDH,S100A11,THRA,ABCG4,P2RX7,MAPK4,BCL2L1,FLT3,EXT2,PDGFA,SP100,SRR,TWIST1,DAB2IP,ECE1,NAGA,NR2C1,SEPHS1,CLCN3,GCA,RIPK2,FZD4,VPS4B,GTF2A2,MYPOP,PTGS2,ALDH5A1,IDE,STK26,BHLHB9,WWTR1,STAT1,KIAA1804,SLC27A1,CHMP4B,ANXA9,PDXK,LRP4,TOP2A,FOXP2,CARD8,PDCD10,IRAK1,OXCT1,TFAP2A,BAX,ABCD1,HMGCL,ERBB3,RAG1,S100A6,MSH6,CAMK2G,P2RX4,PVRL4,HES1,PDGFC,FBLN5,SHMT1,NADK2,FAM109A,PRDX4,PITX2,CD8A,RAB11FIP2,FGFR2,TBX18,NR4A3,PKD2,USF2,ACOT7,ABCG1 |
| 3.361e-05 | -10.30 | regulation of anatomical structure morphogenesis | biological process | GO:0022603 | 913 | 180 | 16441 | 2455 |
SSH1,LGR4,EPHA4,HEXB,RET,GATA3,PLXNA1,VASH1,SH3KBP1,CTNNB1,CDKL5,DPYSL2,DDHD2,DLG1,DNM2,TACSTD2,NTN4,MYH14,SEMA3G,CTTN,TIAM1,S100A13,CYP1B1,SYNE3,STRIP2,EZR,POR,ULK2,ABR,PLCG1,TBC1D17,DNM1L,LIMK1,TBX1,NKD1,SP6,ITPKA,HSPB1,MYL12B,LZTS1,FGD1,SEMA6B,RUNX2,ARAP3,TBC1D1,BVES,SOX9,ETV5,ZNRF3,FBLN1,FAM21C,CORO1B,BMP2,CALR,SPP1,GATA2,MEGF8,VASN,KIF13B,TNFRSF12A,MYDGF,ZRANB1,NTN1,WNT3A,MAPK7,RIMS2,EPB41L5,MFI2,EPHA1,ILK,NPHP3,NFIB,RHOB,RASA1,CDK5R1,AP1AR,SEMA4D,HTT,ITGA7,CSNK1G1,CSF1,ARAP1,FGD6,EFNA1,ARPC2,SEMA3A,XDH,ADAMTS16,EGLN1,EHD1,HOXB7,LFNG,ERBB2,OSR2,EMP2,MNS1,PDGFA,SP100,BCL6,SMO,VAT1,DAB2IP,TWIST1,ETV4,TMBIM1,DVL2,TBC1D10B,SEMA3B,SSH3,DMTN,HTATIP2,DAG1,FZD7,ARHGAP35,PTGS2,FYN,SHROOM3,BHLHB9,PTK7,CORO1C,WWTR1,SIPA1L1,STAT1,TRIOBP,NRG1,EFNA5,PLXND1,WASF3,ANXA3,CTHRC1,FBLIM1,PINK1,TAOK2,CIT,ARHGEF7,SH3D19,EPS8,LRP4,FLOT1,TGFBR1,GDF15,CRABP2,PKN1,ETS1,SRPX2,ICAM1,SIX4,ADGRB2,PPP2R3A,FZD6,HDAC9,PDCD10,PTEN,KNDC1,BMP7,CST3,TFAP2A,BAX,CITED2,TRIM62,TGIF1,HES1,RHOA,RAPGEF2,GRIN1,RGCC,MAP1B,BTG1,DDAH1,FGFR2,ACVRL1,TBX18,FGF18,ERAP1,OSR1,SOX8,SHOX2,L1CAM,FOXA1,NGEF |
| 3.373e-05 | -10.30 | organelle localization | biological process | GO:0051640 | 412 | 92 | 16441 | 2455 |
DOC2A,MTM1,DLGAP5,NDC80,P2RX7,KIF2C,SYTL4,CCNB1,HDAC6,SYTL2,AP1M2,CTNNB1,TACC2,KIF14,DPYSL2,DLG1,DNM2,KIF22,PIK3CD,LMAN1,TFG,PACSIN1,RAB27B,S100A13,RASGRP1,MYO5B,SEC23A,PSRC1,CENPA,UXT,SYNE2,VPS4B,EZR,KIF13A,NUSAP1,MCFD2,NIN,TRIM9,WIPI1,AREG,CHMP4B,SYT13,TC2N,COPG1,GRN,TRAPPC10,CDCA8,CTSZ,PLD2,GPSM2,SPDL1,KIF5B,RB1,PDCD10,CTSC,LLGL2,GATA2,BRAT1,CPLX1,NTN1,PPP6R1,SPRY2,SYTL3,MYO5A,TMED2,SUN2,RAB3B,TACC1,ASPM,SCRIB,COL7A1,BBS2,NUBP1,STX3,PLIN5,MAP1B,AP1AR,SERPINA1,FGFR2,SYT7,PVRL2,HTT,CDCA5,NR4A3,FAM83D,AURKA,CENPE,GEM,NDE1,SHROOM2,ESPL1,SNPH |
| 3.384e-05 | -10.29 | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP | 185 | 48 | 17758 | 2588 |
BIN1,ENO2,FAM169A,ITGA6,DGKA,NUCB2,TRIB2,ETS1,FAM46C,LTBP3,DENND2D,HSF2,OXCT1,GNB5,MCF2L,MGAT4A,PASK,FAM102A,PDE4D,MYLIP,ITM2C,FBLN5,SYNE2,PIK3R1,STMN3,PRKCQ,ITPR3,SESN1,PLEKHB1,TXK,PLCG1,LDLRAP1,MPRIP,NGFRAP1,AMMECR1,LRIG1,INPP4B,APPL2,TMEM14A,TBC1D4,TRAF5,SLC25A38,HSPB1,NR3C2,PKIA,FAM134B,DOCK9,SNPH |
| 3.390e-05 | -10.29 | CHYLA_CBFA2T3_TARGETS_DN | MSigDB lists | CHYLA_CBFA2T3_TARGETS_DN | 221 | 55 | 17758 | 2588 |
BCAM,TRIM2,SORBS1,NQO1,TSPAN15,HEBP1,CD82,BLVRB,ABCG4,FHDC1,LMCD1,C1orf198,CHAC2,PM20D2,GPSM2,SEPT4,AIFM2,LMNA,SH2D4A,PARM1,EPDR1,MARCH8,PHYHIP,KIAA0895,ANK1,RNF128,BDH1,NTN4,MXD3,TINAGL1,TMEM8A,TSPAN33,IGSF3,TRAK2,REC8,PCCB,SLC39A8,CXorf57,KIF1C,SLC11A2,TNS1,UBAC1,C2orf69,CLCN2,FZD7,SEC14L2,CARHSP1,P4HA2,ATP7B,RYK,DHTKD1,KLF5,IRF7,NIPA1,RAB3IL1 |
| 3.403e-05 | -10.29 | human chrXq22.3 | chromosome location | human chrXq22.3 | 26 | 11 | 26250 | 2805 |
TMEM164,RNF128,TBC1D8B,TSC22D3,AMMECR1,CXorf57,MORC4,PSMD10,NUP62CL,MUM1L1,ATG4A |
| 3.453e-05 | -10.27 | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | 75 | 25 | 17758 | 2588 |
SEC61B,HSP90B1,LGALS3,IL15RA,ITGA6,HEXB,PDIA5,NUCB2,ARF4,PRDX4,TRAM2,DDOST,TM9SF2,P4HB,FUT8,PRKCI,SERPINI1,RPN2,MANF,PDXK,CITED2,PDIA6,TRAM1,CKAP4,KDELR1 |
| 3.458e-05 | -10.27 | cell projection membrane | cellular component | GO:0031253 | 288 | 68 | 17570 | 2579 |
TCTN2,NF2,APC2,EPS8L2,SCNN1A,CTNNB1,CDKL5,SLC46A1,DLG1,SMO,DNM2,RP2,PACSIN1,SGCE,DMTN,SYNE2,CYS1,UTRN,EZR,SLC11A2,LCP1,ARF4,GABARAPL1,PTPRJ,SPTBN5,NRG1,PIEZO1,SPRY4,ARF6,TTC8,DDX58,PACSIN2,BVES,EPS8,GABRG2,PLD2,NCKAP1,CNTNAP2,DHRS3,ANK1,VASP,ADORA1,ITGA3,ATP8B1,CNGA1,SPRY2,GPR161,EPB41L5,ADAM17,CASK,RHOA,PLAUR,SPATA13,GRIN1,AIF1L,BBS2,ANTXR1,RASGRP2,PROM1,PHLPP2,PKD2,ITGAV,GPER1,CYBRD1,PROM2,EHD1,ARHGEF4,DRD1 |
| 3.463e-05 | -10.27 | temporal_lobe | COSMIC cancer mutations | temporal_lobe | 107 | 32 | 17775 | 2585 |
NF2,RASA2,RET,TP53,ERBB2,MORF4L2,CDKN2C,ZFYVE16,CTNNB1,PTEN,MKRN3,MSH2,SMO,PIK3CA,PIKFYVE,MAP3K7,MSH6,ENPP4,AKT1,HN1L,PTPRU,SYNE2,SPATA13,CCBL2,IDH1,GNA11,EGFR,GNAS,FGFR2,ARHGAP4,GOLGB1,DMPK |
| 3.463e-05 | -10.27 | SMID_BREAST_CANCER_LUMINAL_B_UP | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_B_UP | 160 | 43 | 17758 | 2588 |
NUDT6,REPS2,HDAC11,RET,MTL5,CACNA2D2,GATA3,GDF15,ISYNA1,BAIAP3,ZMYND10,CRABP2,CCND1,C16orf59,MLPH,IL6ST,FLRT3,WWP1,ARNT2,ACOX2,CACNA1D,MYT1,KCTD3,MCCC2,SEMA3B,DENND1B,SYBU,NKAIN1,DCAF10,TRIM9,ENPP1,ACADSB,TJP3,TTC12,FGFR2,NAT1,RAB11FIP1,SERPINI1,ANXA9,C17orf75,PTGES,FOXA1,FAM134B |
| 3.463e-05 | -10.27 | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | 170 | 45 | 17758 | 2588 |
BIN1,SIGIRR,CKAP2,UBASH3B,NDRG1,ITGA6,EPHA4,ASAH1,F11R,MXD1,DNAJB9,CAPN2,C16orf74,OTUD1,FAM111A,FNIP1,SORL1,PDE4D,PIM1,MYLIP,C9orf72,KCTD3,SMAGP,DUSP1,SUSD3,KIFC2,COQ10B,ITCH,UTRN,DIAPH2,FOS,GABARAPL1,RASGRP2,SOCS3,TXK,IRS2,NR1D2,PELI2,CSGALNACT1,NR4A2,NFKBIZ,KLF11,MAFF,TOB1,PCSK5 |
| 3.463e-05 | -10.27 | YAMAZAKI_TCEB3_TARGETS_UP | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_UP | 170 | 45 | 17758 | 2588 |
CCNC,HSPG2,EPAS1,FAM189A2,MAN1A2,PDIA3,CUL1,COL4A5,CTSZ,CYP26A1,GNS,RCN1,SUSD2,ZYX,UBE2Q2,CYR61,P4HB,FLRT3,RRBP1,FUT8,CST3,TAX1BP3,MDFIC,EPHB4,LGMN,CITED2,TMED2,AMOTL2,SGCE,NR4A1,AMFR,PTPN9,SAT1,FURIN,KDELR3,ERP44,ATP1B1,FNDC3A,ARF4,GNAS,DDAH1,TIMP3,PLOD2,P4HA2,DOCK9 |
| 3.487e-05 | -10.26 | XU_AKT1_TARGETS_6HR | MSigDB lists | XU_AKT1_TARGETS_6HR | 27 | 13 | 17758 | 2588 |
SOAT1,MX1,TCTN2,PLSCR1,HERC5,IRF7,ERBB2IP,IFIT1,OAS3,IFIT3,IFIH1,IFI6,PRKAR1A |
| 3.565e-05 | -10.24 | ion binding | molecular function | GO:0043167 | 5991 | 979 | 16491 | 2452 |
DOC2A,ACACB,TRIM24,TRIM5,AK7,SLC25A13,RET,CACNA2D2,XIAP,SMARCAL1,DHX8,LACTB2,SYTL4,SNX9,CA8,BARD1,KIF26A,LTBP3,PHF1,ZNF275,EPDR1,TP73,CALM2,DAPK2,WEE1,ZYX,TGFBR3,UBE2T,DNAH6,CABP1,CYP2S1,ALDH1A3,SLC46A1,KLF3,ATP13A3,DNM2,TUBG1,CRY2,PPP1CA,PIK3CD,ACOX2,RNF26,WBP4,TIAM1,TIPARP,CPE,APOBEC3G,ERAP2,TUBA4A,NEK4,NWD1,SMARCA2,VPS11,RNF11,SPRTN,CDA,PRKAR2B,LOXL2,RNF19B,PNKD,CYP4F3,ARF4,LCP1,PIAS3,PGF,ENPP1,PLCG1,TRIM47,DNM1L,LIMK1,ATP7B,MYLK,NOD2,MAP3K11,AGFG2,RNASEL,ITPKA,ARF6,ANXA11,ALDH6A1,NUAK1,CYP2J2,ITGA6,MTL5,RAB23,ZNRF3,FAM21C,MERTK,HPCAL4,RABGGTA,MARCH8,GNS,RAC2,DNPEP,ZCCHC17,WDFY1,MEGF8,PRICKLE4,ZIC5,NEK2,MAP3K9,CADPS2,ALPK1,CNGA1,ZMYM1,MAPK7,MOXD1,DGKG,MYLIP,PHKG2,TTLL1,MCCC2,KIF20A,MAPKAPK3,SALL4,SHARPIN,FHL2,PLS1,KIF20B,ILK,PCTP,SPTLC2,GNA11,RHOB,DCP2,CYB5A,STK17A,DHX32,PTPRF,TIMM8A,ITPR1,S100A5,AURKA,DYSF,STK39,B4GAT1,DRP2,ZNF502,TRPC3,RPS6KA3,TMEM173,CSRP2,XDH,ADAMTS16,EGLN1,DMPK,MTM1,RNF224,PAPSS2,TUBB4B,LFNG,GALNT12,ACTR8,RHBDL3,ETNK1,TESK2,MAPK4,GRK6,PRKACA,MOCS1,REPS1,ZNF385B,RCN1,RNF220,CDH1,ENPP5,ACSL4,ARL4D,RAB27B,MYT1,SNX10,RNF169,MX1,SNX8,ENPP4,ERMP1,RIPK2,APOBEC3D,AGPS,PFKFB2,SEPT6,VPS4B,RAB38,XRCC6BP1,SNX12,TRIM7,ZNF618,EBF2,PDLIM3,CDK19,AXL,TRABD2A,PDXK,GEN1,MAPK12,GALK1,TAOK2,HSP90B1,GCAT,MAN1A2,TRAF2,PKN1,ZNF219,NUCB2,IFT27,SGPL1,DTX3L,CAPN2,DIRAS3,ZFX,IRAK1,CTSC,ARSG,GPC3,MCF2L,MGAT4A,FAM20B,ZFAND4,PLEKHF1,ECI2,ADAM15,ZNF230,MAPK11,AK3,NPTXR,RAG1,ITM2C,S100A6,HCN3,ACBD5,MOB4,OPLAH,ADAMTS2,NUDT8,PLSCR1,RAPGEF2,GRIN1,UBE2A,DBR1,AK4,PIM3,BLVRA,NEURL1B,CRISPLD2,ABLIM2,TXK,GALNT3,LDLRAP1,PLOD2,ATXN7L3,NR1D2,ACVRL1,SYT7,ZFP30,DBI,PLA2G15,NR4A3,ARFGAP3,ITGAV,CENPE,FHL1,CMPK2,OSR1,WDR45B,ACOT7,CYBRD1,PHC1,TLL2,MYL9,UNKL,TNK1,TRIM2,AGRN,CNOT8,EPHA4,MCCC1,LMCD1,PHOSPHO1,NENF,ITPR2,MGAT5B,CDIPT,HDAC6,PLS3,RPS6KA2,NPNT,ARL1,MKRN3,LMAN2L,PSMC2,PAPSS1,DDHD2,PAPL,PASK,ABCA2,DDX59,S100A13,ZNF462,PLK1,THRB,PCGF5,KCNIP3,MCTP1,MARK1,ING1,CELSR2,CCBL2,ARFRP1,ESYT1,IDH1,ZBTB7B,CDK1,VCP,RHEB,DZIP1L,DPYSL3,KDM4D,TRIM9,PLCH1,PI4K2B,KLF12,WIPI1,P4HA2,ZNF367,KLF11,PIK3C2B,POMT1,PXDC1,TC2N,MYL12B,RRAGD,PRKAA2,RUNX2,LMTK3,PARP12,RASA2,ZCCHC24,RACGAP1,RAB6A,B4GALT4,FBLN1,RSAD1,MYO5C,UBE2Q2,TIMP1,IGF1R,GATA2,FRAS1,KIF13B,PAK2,PIM1,PLCB2,ABCC1,CYP26B1,CHSY3,PCDH1,TESK1,MGAT4B,ZNF320,STRADB,EIF2AK1,ZSCAN12,PDK3,ZDHHC3,G2E3,CDK5R1,RASGRP2,MAPKAPK2,ZC2HC1A,FA2H,COL13A1,PHLPP2,ITGA7,PRPS2,P4HA3,NLRC5,ZDHHC7,LTBP2,ZDBF2,PLD1,CTBP1,RNF146,UGP2,P3H2,CTDSPL,DGKA,TP53,ZNF28,P2RX7,ERBB2,RASGRP3,CYP26A1,SYTL2,SDF4,CDK14,LMO4,LHX6,SRR,BCL6,PLK4,ZDHHC23,CDH3,VAT1,NOTCH3,OAS3,LMAN1,EGLN3,CTDSP2,SULF2,CTH,CPD,SIRT1,CLCN3,TIMP2,AKT1,FIGNL1,S100A4,ACO1,MYL12A,DAG1,ATP13A2,PTGS2,DUOX1,ZNF628,ATP1A1,IDE,MMP17,PTK7,STK38,ADAMTS14,MAOA,XRCC3,ANXA9,ZBTB6,SYT13,RPL22,AIFM3,LTA4H,ZNF701,ZC3HC1,CTDSP1,MAN2B2,ZMAT1,PINK1,DYRK3,PACSIN2,TOR4A,CDH22,TAB3,SCD5,GNE,GNAL,MCTP2,ERCC6L,ERI2,SELL,GTF3A,JAG2,CRABP2,PPP2R3A,NRP2,ZDHHC21,FOXP2,CDK16,ALPP,GTF2F2,UBE2J1,SGK1,TRIM21,BUB1,HMGCL,ABCD1,KLF9,SYK,CAMK2G,ATP2B1,FAH,P2RX4,FBLN5,RHOA,NR3C1,AMFR,CRIP2,PPARA,PRICKLE1,TRIM35,CAPNS1,RNPEP,DGKE,DDX23,DDAH1,FAT4,ZNF214,NEIL3,ZMYND19,PPP2R3C,PKD2,ACADM,UBE2C,PTGES,HIPK3,ZBTB33,ACVR1,HSPG2,ATP8A1,TAP1,GATA3,CAMK1D,SEPT4,PJA2,OAT,PICK1,NCS1,ASPHD2,PAK6,HELZ2,CYP1A1,CTGF,ZNF823,STIM1,PRICKLE3,ZFP36,POLL,STEAP2,PIK3CA,AOX1,SNX16,MARCH2,ZBTB18,PACSIN1,SMYD5,METAP2,KIFC2,ACVR1C,PBK,HSPA12A,KIF13A,PIF1,GALNT7,AURKB,MCFD2,ZFAND5,TP53I3,POR,RAB2B,ULK2,PRIM1,GDE1,PLK2,PTER,GNPTAB,PPP2R4,NKD1,PRDM5,BMP1,DHTKD1,MAPK13,TRAF5,FGD1,DDX58,KLF2,RECQL,CDK17,CALB2,DGKQ,ADO,PRKAA1,KIF23,SLC1A3,NOTCH2,APBA1,S100A2,PDXDC1,BMP2K,PRRG4,SH3RF2,MECOM,CALR,C9orf69,ITGA3,CYR61,SNX18,ZNRF2,NECAB3,CTPS1,MSH2,DAPK1,PRKG1,ADCK2,CACNA1D,PIKFYVE,MAST4,ZNF117,SYTL3,RIMS2,PMPCB,PRODH,ZNF84,MFI2,TBC1D8B,ADCK3,CALM1,AMER1,DCHS1,PIP4K2C,PYGL,WHSC1,EPHA1,ATP8B3,PKM,KDM3A,ANTXR1,JADE2,STX3,PDE11A,DGKH,MMP15,NT5C2,PRKAG2,CSNK1G1,DCK,ZDHHC20,MATN2,ARAP1,PIAS2,AGBL5,FGD6,PCDH19,NR4A2,CDK18,ZBTB34,MAP3K5,IFIH1,NRBP1,PKD1L2,EHD1,PLA2G4A,KIF3C,REPS2,CAPN12,NLRX1,S100A11,THRA,RPS6KA1,IQGAP1,SUZ12,ATP2C2,RNF182,FTH1,EGR3,AIFM2,FLT3,NUDT12,DDR1,CYP39A1,ZFYVE9,APOBEC3B,CYHR1,NOV,APLP2,ACAP2,ZNF75D,TRANK1,RALB,FICD,DAB2IP,RNASEH2A,PDE4D,EPHB4,NR2C1,MYO5B,SEC23A,PANK1,UTRN,CLSTN1,TEP1,COX11,KIF1C,PRKCQ,SLC11A2,ATP1B1,RAD17,PYGO1,PKMYT1,CBL,ITPR3,ATP10D,SP4,ZNF469,NIN,ZMPSTE24,EPHA10,AMZ2,ZNF641,FYN,JAK1,ACAD10,NGFRAP1,STK26,HAGHL,KIAA1804,ZNF704,PPP1CB,EFCAB14,KLF5,RAB29,ZC3H12B,MLKL,B4GALT3,NR3C2,ATMIN,PRKAR1A,PCOLCE,PLSCR4,ATP9A,ARL4C,CBLL1,EFHD2,CYB561,APOBEC3H,PLD2,DNAH3,RND1,RNF128,PHF7,MGAT1,PTEN,PPP1R10,SGK3,ATP8B1,ERCC2,ERBB3,CNOT6L,MAP3K7,GFI1,TTPA,TRIM62,MSH6,SMC4,PCCB,ARAP2,ARHGEF28,SHMT1,CASK,LONRF3,PAPD7,ZC3H11A,FURIN,ZKSCAN2,YES1,AIF1L,ARSK,KIF11,CPTP,CDK5RAP1,NUCB1,TIMP3,ACADSB,FGFR2,ABCB1,RYK,PGM2L1,ERAP1,RABL6,LRRK1,ARSB,MELK,ESYT2,USP16,LTBP1,NMRK1,ST13,CAMKK1,UBE2Z,UBE2Q1,VARS2,KIF2C,DNER,TRIM68,HTR1D,ABCD4,CHPF,ADPRHL1,ZFYVE16,RAB15,CDKL5,ZCCHC12,SIVA1,IMPAD1,TRPC1,KIF22,RAB20,ASH2L,RP2,MYH14,NFU1,MYRIP,RASGRP1,SP5,STK35,CYP1B1,NLRP4,ATL1,SOD1,CXXC5,TRIM8,LAP3,ASXL1,ACBD3,RNF165,ROR1,STK17B,ADRBK2,TCN2,SEC14L2,MDK,MAN2A2,CXXC4,NEIL1,ZNF114,TRIM45,IARS2,ZNF165,ADIPOR1,SP6,CHPT1,NRGN,PSMC1,CAPN1,CPPED1,NR2C2,LASP1,ARAP3,SERPINE2,ZNF395,PEX6,BVES,ABCG2,CALM3,TEC,PHLPP1,ZNF432,CA2,PFKL,FAM20C,PRKCI,EBF4,SRP54,LIMCH1,ZNF692,ACAD8,ZRANB1,GAD1,CCDC88A,SNED1,SNX7,GYLTL1B,PDE5A,RNF113A,NUBP1,PDIK1L,STEAP1,AMDHD1,EGFR,FECH,GNAS,NUDT16,INSR,CGREF1,PAPD5,RAB31,RHOBTB2,ALPK3,EGFL7,YOD1,KIF12,JAK3,RARG,SNX30,KLF7,DRD1,LMO7,SLC25A24,ZSWIM5,ABCG4,SOD2,MORC4,COL18A1,GMPR,MRAS,OSR2,ZMYND10,MICALL2,EXT2,ZNF687,SETDB2,CYP4F11,ZDHHC12,KIF14,FABP6,ZBTB49,GOT1,STEAP3,ECE1,APIP,ETHE1,LOXL1,SCYL3,HSPA2,SEPHS1,CHP1,MAP3K3,SOAT1,ZNF525,GCA,RFK,GLO1,MAP3K6,ARHGAP35,JADE1,PEX2,OVOL1,CANT1,CYP2U1,ABCA1,GLIS3,ANXA3,FBLIM1,ENO2,SHPRH,CIT,LRP4,TGFBR1,ITGA2B,HDAC9,ZNF212,IRF2BPL,KIF5B,TOP2A,SNX13,ADRBK1,TAF1B,MLPH,BMP7,GALNS,ZDHHC13,ACTA2,TRIM3,HSPA13,MYO5A,PGM1,PHF20L1,ADAM17,RAB3B,NR4A1,GCLC,RC3H2,MBNL3,OGDHL,NADK2,RUNX3,SPAG1,ENDOD1,MARC1,SWAP70,RND3,TRIM69,FIBCD1,RAP2C,CSGALNACT1,DTX4,UBE2D2,TADA2B,GEM,ZMIZ1,PLOD3,L1CAM,ABCG1,ZNF596 |
| 3.584e-05 | -10.24 | ELLWOOD_MYC_TARGETS_DN | MSigDB lists | ELLWOOD_MYC_TARGETS_DN | 38 | 16 | 17758 | 2588 |
CDS2,NKX3-1,ALDH2,EZR,ERP44,MCFD2,TP53INP2,DNAJC10,IDE,PROM1,CA2,NR1D2,PEX2,CLDN4,LIMCH1,PDIA6 |
| 3.591e-05 | -10.23 | positive regulation of cyclin-dependent protein kinase activity | biological process | GO:1904031 | 30 | 14 | 16441 | 2455 |
CCND1,CCNC,ADAM17,PSRC1,AKT1,RGCC,PSMD10,PKD2,CCNL1,PIM1,PDGFB,STIL,HSPA2,EGFR |
| 3.599e-05 | -10.23 | morphogenesis of embryonic epithelium | biological process | GO:0016331 | 147 | 41 | 16441 | 2455 |
CTHRC1,GRHL2,ST14,SOX9,SDC4,RET,RAB23,GATA3,JAG2,NCKAP1,PRKACA,STIL,FZD6,VASP,CTNNB1,LMO4,ALDH1A3,TFAP2A,TWIST1,MAP3K7,DVL2,EPB41L5,TGIF1,SALL4,PRICKLE1,KIF20B,SCRIB,BCL10,ARHGAP35,IRX3,TSC1,SHROOM3,FGFR2,HTT,PTK7,TBX18,SPINT2,SOX8,OSR1,COBL,RARG |
| 3.642e-05 | -10.22 | luminal_NS_carcinoma | COSMIC cancer mutations | luminal_NS_carcinoma | 54 | 20 | 17775 | 2585 |
FAM171B,NFKBIE,AKT1,AMFR,PIK3R1,TP53,GATA3,SIX4,RB1,CYP1A1,CDH1,PTEN,NFKBIA,AIM1,PIK3CA,ATP8B1,GRIN2D,GEN1,GAB1,MSH6 |
| 3.642e-05 | -10.22 | breast-carcinoma-luminal_NS_carcinoma | COSMIC cancer mutations | breast-carcinoma-luminal_NS_carcinoma | 54 | 20 | 17775 | 2585 |
FAM171B,NFKBIE,AKT1,AMFR,PIK3R1,TP53,GATA3,SIX4,RB1,CYP1A1,CDH1,PTEN,NFKBIA,AIM1,PIK3CA,ATP8B1,GRIN2D,GEN1,GAB1,MSH6 |
| 3.649e-05 | -10.22 | regulation of multicellular organismal process | biological process | GO:0051239 | 2431 | 429 | 16441 | 2455 |
ACACB,GAA,ACVR1,SSH1,LGR4,TSC22D3,RET,CACNA2D2,GATA3,IL18,PLXNA1,CAMK1D,CCNB1,VASH1,FAM101B,GRM5,NCS1,TP73,CALM2,CTGF,ZFP36,PIK3CA,DNM2,TACSTD2,SEMA3G,PACSIN1,TIAM1,ACVR1C,TFAP2C,LOXL2,F12,SAV1,POR,ULK2,ABR,ENPP1,PLCG1,AREG,PLK2,LIMK1,TBX1,TRAF3IP1,NKD1,NOD2,BMP1,MAPK13,ITPKA,ARF6,HSPB1,F2RL1,LZTS1,DDX58,SEMA6B,SCN5A,KLF2,CYP2J2,HLA-E,SOX9,PRKAA1,ZNRF3,BMP2K,CALR,ITGA3,CYR61,MEGF8,VASN,FLRT3,FBXO7,PRKG1,SORL1,TNFRSF12A,MYDGF,CACNA1D,MAPK7,MYLIP,RIMS2,GPR161,SOCS5,EPB41L5,KCNJ12,MMD,CALM1,ANO6,WHSC1,CALCRL,PLS1,KIF20B,EPHA1,NPHP3,ILK,GNA11,NFIB,RHOB,FAS,PTPRF,NCOA3,SEMA4D,NAB2,PIAS2,AURKA,SFMBT1,NR4A2,STK39,EFNA1,GDF11,PER3,IFIH1,TRPC3,TMEM173,XDH,EGLN1,DMPK,IRF1,FOXO6,GRHL2,NLRX1,LFNG,THRA,INPP5D,IQGAP1,PKP2,EGR3,CD274,PRKACA,FLT3,TNFSF9,CCND1,CD46,NOV,SP100,FAM46A,CDKN1B,DAB2IP,PDE4D,LGMN,ETV4,TMBIM1,SEMA3B,DOCK4,ENPP4,SSH3,RIPK2,DMTN,CLSTN1,HTATIP2,PRKCQ,ATP1B1,SP4,FZD7,FYN,CORO1C,AXL,WWTR1,SIPA1L1,INPP4B,STAT1,SLC27A1,NRG1,RAB29,RGS14,ARNT,COBL,OTUD5,WASF3,CTHRC1,NKX3-1,TRAF2,FLOT1,PBX3,HERC5,ETS1,SPR,GSTP1,SRPX2,TEAD3,ICAM1,ADGRB2,HLA-A,SIX4,SGPL1,CTNNBIP1,SNTA1,PDCD10,RNF128,IRAK1,PTEN,KNDC1,CST3,BAX,MAPK11,CITED2,MAP3K7,RAG1,GFI1,ITM2C,TRIM62,MSH6,TGIF1,RAPGEF2,PIK3R1,GRIN1,VAMP3,FURIN,FOS,TXK,GPLD1,CDK5RAP1,BTG1,PROM1,FGFR2,NR1D2,ACVRL1,TBX18,NR4A3,ERAP1,GRIN2D,GPER1,FZD5,OSR1,ARSB,SHOX2,FOXA1,MYL9,EMX1,SIGIRR,EPAS1,AGRN,EPHA4,LMCD1,PHOSPHO1,NDRG2,F11R,HDAC6,PDGFB,CTNNB1,NPNT,CDKL5,IL6ST,DPYSL2,PASK,MITF,DLG1,DUSP10,NTN4,CTTN,RASGRP1,CYP1B1,THRB,NLRP4,SOD1,ITCH,EZR,KLK6,ARHGDIB,EAF2,CDK1,RHEB,DPYSL3,IRX3,KCNMB4,GPRC5B,AGPAT2,HPSE,HOXA9,RAB11FIP1,SP6,TC2N,MAFF,PRKAA2,GRN,RUNX2,PPP1R12A,LGALS3,SERPINE2,BVES,UBASH3B,ETV5,CALM3,TEC,PHLPP1,DHRS3,FBLN1,IL18R1,BMP2,SPP1,RB1,TIMP1,CA2,GATA2,FAM20C,KIF13B,SUCO,PRKCI,FNIP1,NPTN,C10orf54,WNT3A,NTN1,CCDC88A,HMG20B,PDE5A,KIAA1109,CDK5R1,SOX13,GNAS,MAPKAPK2,INSR,FA2H,PLPP3,CSF1,TMEM30A,NFKBIA,NLRC5,FAM213A,JAK3,SEMA3A,TOB1,RARG,DRD1,GAS2L1,PAX6,NF2,HOXB7,IL15,TP53,ERBB2,P2RX7,IL27RA,OSR2,EMP2,SYTL2,PER2,PDGFA,SVBP,KIF14,PLCG2,BCL6,SMO,CDH3,TWIST1,DIXDC1,ECE1,EPB41L4B,NOTCH3,TMEM64,NFKB2,F2R,DVL2,SULF2,TIMP2,AKT1,CCSAP,CDC20,PTGER4,CD40,DOCK5,DAG1,ARHGAP35,PTGS2,ATP1A1,BHLHB9,STAT6,PTK7,EFNA5,IRF7,PLXND1,CTDSP1,BIN1,ANXA3,ADGRG1,CIT,LRP4,TGFBR1,CRABP2,TRIB2,NRP2,PPP2R3A,FZD6,HDAC9,CD109,CARD8,ADORA1,ADRBK1,BMP7,MYCL,KIAA0319,TFAP2A,UBE2J1,SGK1,IL17RA,H2AFY,TRIM21,IQGAP3,SYK,CAMK2G,FAM134C,TLE6,P2RX4,HES1,ADAM17,RHOA,WNT10B,ASPM,PLAUR,LITAF,RGCC,PRICKLE1,BBS2,BCAR1,MAP1B,BCL10,PRDX4,CD83,CNOT2,HLA-B,DDAH1,BANK1,FAT4,TWSG1,PRCP,FGF18,NMI,DTX4,ARRB1,PPP2R3C,SOX8,NDFIP1,L1CAM,NGEF |
| 3.653e-05 | -10.22 | urogenital system development | biological process | GO:0001655 | 305 | 72 | 16441 | 2455 |
LGR4,THRA,IQGAP1,RET,EPHA4,GATA3,OSR2,SDC1,PDGFB,TP73,EPCAM,CTNNB1,NPNT,DLG1,SMO,AKR1B1,TACSTD2,NOTCH3,TIPARP,SULF2,PYGO1,IRX3,WFS1,WWTR1,STAT1,OVOL1,PCSK5,NKX3-1,CDKN1C,ITGA6,LRP4,SDC4,SOX9,TGFBR1,SIX4,MECOM,SGPL1,BMP2,CTNNBIP1,CA2,IGF1R,ITGA3,PTEN,GATA2,FRAS1,GPC3,BMP7,BAX,TFAP2A,ACTA2,GCNT1,HES1,FMN1,AMER1,DCHS1,ILK,NPHP3,TSC1,PROM1,FAT4,FGFR2,TBX18,SERPINB5,PKD2,HOXB13,GDF11,SOX8,OSR1,RARG,AHR,FOXA1,ADAMTS16 |
| 3.659e-05 | -10.22 | EF_Hand_1_Ca_BS | interpro domains | IPR018247 | 175 | 46 | 18293 | 2672 |
MYL9,SLC25A24,REPS2,CAPN12,S100A11,CALB2,DGKA,CALM3,RASGRP3,NUCB2,S100A2,REPS1,HPCAL4,NCS1,PPP2R3A,SDF4,PLS3,CALM2,RCN1,CAPN2,NECAB3,CABP1,DGKG,RASGRP1,S100A6,GCA,KCNIP3,S100A4,CALM1,PLS1,CAPNS1,MCFD2,MYL12A,LCP1,RASGRP2,NUCB1,PLCG1,PLCH1,DUOX1,GNPTAB,CGREF1,NKD1,S100A5,PPP2R3C,CAPN1,EHD1 |
| 3.667e-05 | -10.21 | C2_dom | interpro domains | IPR000008 | 160 | 43 | 18293 | 2672 |
PLA2G4A,DOC2A,RASA2,MCTP2,BAIAP3,SYTL4,PKN1,SYTL2,SYDE2,WWP2,TNS3,CPNE2,PTEN,RGS3,RIMS3,PLCG2,PIK3CA,DAB2IP,CADPS2,WWP1,PIK3CD,PLCB2,SYTL3,RIMS2,MCTP1,CAPN6,ITCH,PRKCQ,TNS1,ESYT1,RASA1,ABR,PLCG1,PLCH1,SYT7,RAB11FIP2,INPP4B,RAB11FIP1,DYSF,PIK3C2B,SYT13,TC2N,ESYT2 |
| 3.721e-05 | -10.20 | S_TKc | smart domains | SM00220 | 268 | 68 | 9131 | 1455 |
CAMKK1,RPS6KA1,MAPK4,GRK6,CAMK1D,PRKACA,CDK14,PAK6,DAPK2,RPS6KA2,CDKL5,PASK,PLK4,MAP3K3,PLK1,NEK4,MARK1,AKT1,PRKCQ,AURKB,MAP3K6,ADRBK2,CDK1,STK17B,ULK2,STK26,CDK19,STK38,PLK2,MYLK,MAPK13,MAPK12,PRKAA2,CDK17,TAOK2,DYRK3,NUAK1,CIT,PRKAA1,PKN1,ADRBK1,CDK16,PAK2,DAPK1,NEK2,PRKG1,SGK3,PRKCI,SGK1,MAPK11,PIM1,MAPK7,MAST4,PHKG2,CAMK2G,CASK,MAPKAPK3,PIM3,STK17A,MAPKAPK2,AURKA,STK39,CDK18,MAP3K5,HIPK3,RPS6KA3,MELK,DMPK |
| 3.746e-05 | -10.19 | thyroid-chronic_thyroiditis | COSMIC cancer mutations | thyroid-chronic_thyroiditis | 50 | 19 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,CCDC6,PIK3CA,SMO,JAK3,PRKAR1A |
| 3.746e-05 | -10.19 | chronic_thyroiditis | COSMIC cancer mutations | chronic_thyroiditis | 50 | 19 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,CCDC6,PIK3CA,SMO,JAK3,PRKAR1A |
| 3.748e-05 | -10.19 | TSENG_IRS1_TARGETS_DN | MSigDB lists | TSENG_IRS1_TARGETS_DN | 131 | 37 | 17758 | 2588 |
CD63,THRA,FRMD6,FTH1,EFNB1,MESDC2,CDKN2C,B3GALNT1,IL6ST,TSPAN6,CST3,COL6A1,CAPG,LIMCH1,PHKA2,CTDSP2,CCDC88A,FAH,EPHX1,SGCE,RAB3B,CAPN6,CRIP2,LITAF,SNTB1,CD40,SESN1,IL1R1,CARHSP1,ENPP1,TAPBP,POPDC3,CCDC6,GNPTAB,ITPR1,MAOA,LIFR |
| 3.800e-05 | -10.18 | SHEPARD_BMYB_TARGETS | MSigDB lists | SHEPARD_BMYB_TARGETS | 71 | 24 | 17758 | 2588 |
PHF20L1,DLGAP5,FOXM1,CKAP2,ASPM,CDC20,CDCA3,KIF23,CDCA2,NOTCH2,AURKB,CCNB1,ANLN,KIF11,CDK1,MDK,ATP1A1,CCNB3,KIF14,PRC1,HMGA1,NDE1,MELK,GOLGB1 |
| 3.845e-05 | -10.17 | MODULE_121 | MSigDB lists | MODULE_121 | 98 | 30 | 17758 | 2588 |
GRN,IL15RA,IL15,EPS8,ERBB2,EMP3,IL18,RUNX3,BCAR1,PDGFB,TNFSF9,MXD1,CDK5R1,EDNRA,MDK,PDGFA,BTG1,CD8A,TIMP1,CYR61,AREG,CSF1,NAB2,BCL6,OSMR,TACSTD2,EPHB4,CD81,CSRP2,LAMP3 |
| 3.860e-05 | -10.16 | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | 50 | 19 | 17758 | 2588 |
CD99,KLF2,KIF3C,COL6A2,FAM92A1,RBM24,TNIP1,NUAK1,ZCCHC24,UTRN,STRADB,RNF182,LOXL2,ARHGEF40,MAP1B,SCG2,ARNT2,SEMA3A,SHOX2 |
| 3.860e-05 | -10.16 | DAUER_STAT3_TARGETS_DN | MSigDB lists | DAUER_STAT3_TARGETS_DN | 50 | 19 | 17758 | 2588 |
DDX58,MX1,PARP12,LAP3,TRIM5,USP18,HERC5,SAMD9,IFIT3,HERC6,BCL2L13,TRANK1,STAT1,TDRD7,IRF7,IFIT1,OAS3,IFIH1,LAMP3 |
| 3.862e-05 | -10.16 | MAPK family signaling cascades | REACTOME pathways | R-HSA-5683057 | 273 | 66 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,MAPK4,PSME1,PRKACA,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,IL6ST,PSMC2,DUSP10,DAB2IP,RASGEF1A,ETV4,RASGRP1,FRS3,AGO4,DUSP4,CDK1,IRS2,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,HSPB1,PSMC1,PPP2R5D,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,FGF19,DUSP5,ITGA2B,PAK2,ERBB3,RAG1,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,PSMA4,EGFR,RASA1,NCOA3,FGFR2,FGF18,ARRB1,GRIN2D,JAK3 |
| 3.867e-05 | -10.16 | GSE20366_TREG_VS_TCONV_DN | MSigDB lists | GSE20366_TREG_VS_TCONV_DN | 191 | 49 | 17758 | 2588 |
FAM171B,LGALS3,DNAJC3,ESRP1,ADO,FAM78A,SPR,FAM101B,DENND2D,HLA-A,SESN3,RALGPS2,PPP1R10,RINL,MGAT4A,SGK3,CCDC82,ALDH7A1,STT3B,ECE1,CNGA1,ANO4,MYLIP,FAM69A,CYP1B1,HPS3,GCLC,NUB1,RAB3IP,ANLN,ASB13,DOCK5,RNF19B,TRUB1,C3orf58,CASP4,DGKE,EDNRA,SGPP1,RASGRP2,PDE11A,XKRX,MID1IP1,ANKRD6,TRIOBP,ABCB1,PER3,ARSB,ESPL1 |
| 3.872e-05 | -10.16 | immune response-regulating cell surface receptor signaling pathway | biological process | GO:0002768 | 463 | 101 | 16441 | 2455 |
SPRED1,INPP5D,PSME2,GATA3,CUL1,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PRKACA,CACNB4,PDGFB,SPTB,PDGFA,CALM2,PSMD1,ELMO2,SHC3,PSMC2,PLCG2,PIK3CA,CDKN1B,DAB2IP,PIK3CD,PDE4D,RASGEF1A,NFKB2,RASGRP1,FRS3,RIPK2,AKT1,CASP9,CR2,AGO4,PRKCQ,CD40,ITPR3,IRS2,PLCG1,FYN,PTPRJ,JAK1,LIMK1,PSMD3,SPTBN5,NRG1,GAB1,PSMC1,TNRC6C,THEMIS2,TAB3,RASA2,PSMD7,PSMD10,BTN3A1,CALM3,PLD2,TEC,NCKAP1,PHLPP1,FGF19,DUSP5,VASP,PTEN,PAK2,BAX,ERBB3,MAP3K7,NCAM1,SYK,PSMA5,CAMK2G,RASGRF1,PSMB4,NR4A1,MICB,RAPGEF2,CALM1,PIK3R1,GRIN1,YES1,CYFIP2,FOS,BCAR1,PSMA4,EGFR,RASA1,BCL10,TXK,GPLD1,FGFR2,PHLPP2,NFKBIA,FGF18,ITPR1,UBE2D2,NR4A3,GRIN2D,ARPC2,JAK3 |
| 3.889e-05 | -10.15 | response to insulin | biological process | GO:0032868 | 408 | 91 | 16441 | 2455 |
SPRED1,SORBS1,SLC2A4,SLC2A8,PSME2,WDTC1,NRG2,ERBB2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,SESN3,PSMD1,SHC3,PSMC2,PIK3CA,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,SIRT1,AKT1,ACVR1C,PRKCQ,RHEB,SOCS3,IRS2,ENPP1,FYN,IDE,JAK1,PSMD3,CAB39,SLC27A1,EIF4EBP2,SPTBN5,NRG1,PSMC1,GAB1,RRAGD,PRKAA2,INPPL1,SORT1,RASA2,PRKAA1,PSMD7,ATP6V1E2,CALM3,PSMD10,DUSP5,FGF19,HDAC9,IGF1R,PRKCI,ERBB3,NCAM1,CAMK2G,MYO5A,PSMA5,GCNT1,RASGRF1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,PPARA,STRADB,GGH,BCAR1,PSMA4,EGFR,RASA1,GPLD1,TSC1,INSR,PRKAG2,FGFR2,FGF18,RAB31,GRIN2D,ATP6V1C1,JAK3,TBC1D4,CPEB2,DRD1 |
| 3.926e-05 | -10.15 | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP | MSigDB lists | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP | 186 | 48 | 17758 | 2588 |
BIN1,CCNI,SIGIRR,NKX3-1,GGA1,DNAJB2,CNOT8,INPP5D,ITGA6,CAPN2,MARCH8,ACAP2,PTEN,ALPP,MCF2L,CAPG,CITED2,CNPY3,MYBL1,CTDSP2,EEF1D,POU6F1,PIGC,NAGPA,SUN2,SMARCA2,S100A4,UXT,PIK3R1,BNIP3L,FBXO9,SESN1,NDRG3,PLEKHB1,NMT2,PLCG1,LDLRAP1,MPRIP,STK38,CSGALNACT1,FAM117A,TTC9,TMEM159,RGS14,NR3C2,FAM134B,CTDSP1,EHD1 |
| 3.926e-05 | -10.15 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 186 | 48 | 17758 | 2588 |
NFKBIE,PTTG1,TGFBR1,EGR3,BCL2L1,MGST2,UHRF1BP1L,HDAC9,IL17RB,RAC2,METTL7A,RALB,CENPJ,SGK1,TNFRSF18,RTKN2,TAGLN2,C12orf75,SNX10,MAST4,MYO5A,GCA,SEC61B,LYRM1,SAT1,WHSC1,RUNX3,ERP44,ATP1B1,IDH1,MYL12A,RANBP9,FRMD4B,KLHL2,SLCO4A1,HLF,SWAP70,UEVLD,RCBTB2,WIPI1,DBI,SIPA1L1,RAB11FIP1,NOD2,CSTF2,PKD2,ATP1B3,TMEM173 |
| 3.926e-05 | -10.15 | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | 186 | 48 | 17758 | 2588 |
MRC2,LGALS3,NQO1,UGP2,DAP,ZCCHC24,NDRG2,RASGRP3,IL13RA1,MRAS,NANS,SPR,TNS3,AP1M2,CTSC,MITF,CST3,DAPK1,ADCK2,TACSTD2,SLC16A5,CCDC88A,PDGFC,TIMP2,CTNNAL1,ACO1,VAMP3,TNS1,ALCAM,PCTP,CD83,FUCA1,MID1IP1,CTNS,SERPINA1,H1F0,PRDX3,PRCP,CSF1,SPINT2,CLIP4,CLMN,ADIPOR1,LRRK1,FZD5,NRGN,ANXA11,CD33 |
| 3.926e-05 | -10.15 | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | 186 | 48 | 17758 | 2588 |
SIGIRR,HECA,HAPLN3,GALNT12,EPHA4,DGKA,MORC4,GATA3,AES,CD274,TRIB2,PHF1,TMEM63A,ITGA3,TOX2,ANKRD12,WWP1,MAST4,TRIM62,ABCC1,SUSD3,ASXL1,PAPD7,TCF7,PRKCQ,ESYT1,ITPR3,OPTN,PLCG1,SPIN3,MPRIP,COQ10A,TJP3,AMMECR1,LRIG1,AGFG2,FAM117A,MAPK13,PIEZO1,TTC9,TMEM14A,TBC1D4,HSPB1,CBX7,TMEM173,EHD1,DOCK9,PHC1 |
| 3.937e-05 | -10.14 | cellular process | biological process | GO:0009987 | 14182 | 2179 | 16441 | 2455 |
PNPLA2,HEXB,MCOLN3,CCNO,SPSB1,SLC35E4,GRM5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,LCP1,ABR,PIAS3,MID1IP1,NOD2,TMOD2,STARD13,ANXA11,GGA1,SEC61G,ITGA6,MTL5,RAB23,GPSM2,TTYH3,ATG4A,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,NUP85,TTLL1,PPP6R1,MCCC2,REC8,PYM1,FHL2,ELK1,NPHP3,DPYSL4,PLIN5,SLC4A4,ETS2,DGAT2,GDF11,TMEM173,DMPK,C5orf30,MAPK4,MGST2,RBM23,MUC16,ENPP5,TAX1BP3,MYT1,SNX8,RIPK2,APOBEC3D,AGPS,SEPT6,PTPN9,VPS4B,HTATIP2,SYP,XRCC6BP1,TANC1,GTF2A2,SNX12,ZNF618,NFIX,PDLIM3,CDK19,SHROOM3,CORO1C,WFS1,AXL,PRIMA1,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,DCAF7,ESRP1,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,CTSZ,ZNF219,HDGFRP2,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,KLC3,BAX,IGFBP2,MED22,ACBD5,PVRL4,TACC1,PIK3R1,DUSP23,MRS2,NUB1,RAB3IP,PIM3,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,PLA2G15,WDR45B,SRSF9,ACOT7,TLL2,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,MGAT5B,SLC9A3R2,PLS3,INPP5E,ENTPD4,RPS6KA2,NUP210,P4HB,PAPL,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,KCNMB4,HOXA9,KLF11,RUNX2,LMTK3,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,FRAS1,KIF13B,TBCD,SLC30A6,FCHO1,SELK,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,PRX,CDK5R1,COL13A1,PHLPP2,KBTBD2,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,KMT5C,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,ATP13A2,ZNF628,PTPRJ,IDE,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,UBE2J1,IL17RA,ALDH7A1,CPLX1,TSPAN13,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,GGH,COL7A1,DDX23,SCG2,NEIL3,PTGES,HIPK3,ZBTB33,SLC35D2,TXN,SSH1,HSPG2,LGR4,TMEM86B,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,HELZ2,TYMP,PALD1,FOSB,KCNS3,SERINC2,IRF2,SPATA18,BNIP3L,SLC35C1,KIF13A,SH2D3C,BMP1,NFKBIZ,F2RL1,SLC31A2,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,BHLHE41,PPP4R1,MSH2,ADCK2,PRKG1,OSTF1,CACNA1D,MAST4,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,CEP89,ADCK3,DCHS1,PYGL,EPHA1,ATP8B3,MMP15,SLCO4A1,PLEKHH2,AGBL5,PIAS2,APPL2,SFMBT1,KLK7,CDK18,SAMD8,ZBTB34,PER3,EHD1,FOXO6,TCF25,ATP2C2,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,PDE4D,OSBPL7,SULT2B1,NAGA,MED30,SEMA3B,ATG4D,DOCK4,DRAP1,PANK1,KIF1C,ATP1B1,PYGO1,PKMYT1,ASB13,CBL,B3GALNT2,FZD7,CEP162,ACAD10,NGFRAP1,TRIOBP,CBX7,IGFBP6,DEPDC1,EPS8,HERC5,PLD2,FBXO6,SPDL1,FGF19,EFNB1,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,RNF128,GNB5,CD9,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZKSCAN2,DIAPH2,UBAC1,ARSK,KIF11,CPTP,DCTN6,ACADSB,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,WDR62,ESPL1,RGMA,CCNC,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,EPCAM,ZFYVE16,HSF2,CDKL5,TRPC1,ASH2L,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,NRGN,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,BRAT1,LIMCH1,C10orf54,GAD1,ETV7,MDFI,SNX7,SPA17,PDE5A,NUBP1,STEAP1,RANBP9,SOX13,UAP1,RAB31,DCUN1D1,NXPH4,CTSA,TOB1,RARG,SNX30,LZTFL1,DYNLRB1,SORBS1,PAX6,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,COX14,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CHP1,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,JADE1,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,FBLIM1,GCLM,ARHGEF7,TGFBR1,SBF1,XPR1,KIF5B,BMP7,MYCL,TOX2,RRBP1,MYO5A,PGM1,DCAF6,RC3H2,RGCC,TTC7A,LEPR,ENDOD1,LEMD2,ARHGAP24,CTSL,CASP7,TRIM69,SPINT2,RAP2C,DTX4,UACA,ARRB1,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,CACNA2D2,SMARCAL1,NRG2,CNTROB,MORF4L2,SYTL4,BARD1,PHF1,DAPK2,ZYX,AP1M2,TGFBR3,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,SPEF2,TNIP1,RNF11,MTRF1L,MYOM1,CYP4F3,COL12A1,DNM1L,MYLK,ARF6,PDPR,ALDH6A1,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,ILK,DCP2,CYB5A,STK17A,DHX32,NCOA3,MTFMT,SEMA4D,HTT,SETD3,TEX30,ITPR1,AURKA,ALG2,B4GAT1,NDE1,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,NUF2,IL13RA1,KTN1,CDS1,CCND1,SCNN1A,RNF220,RTKN2,ACSL4,RAB27B,CDKN2D,RNF169,SCN3A,ENPP4,CAMSAP3,NRBF2,FZD4,CYS1,CDCA2,RAB38,PEX5,SLC9A6,WWTR1,TRABD2A,PDXK,RGS14,ARNT,TNRC6C,NKX3-1,TAOK2,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,DTX3L,CAPN2,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,RAPGEF2,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SKA1,TXK,DCAF10,PITX2,ATXN7L3,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,UNC93B1,TRIM2,AGRN,PPM1J,GNPDA1,EPHA4,HDAC6,PDGFB,SHC3,MKRN3,ELF5,ANO4,TRAM1,DDX59,NEB,PCGF5,MCTP1,CITED4,ERP44,ANLN,CLCN2,VCP,RHEB,PLEKHB1,IRX3,DPYSL3,TBC1D17,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,HLA-F,UBASH3B,ASAH1,DOCK11,PGAP1,BMP2,GATA2,CMTR2,EXOC8,MDFIC,PLCB2,ALDH3A2,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,H1F0,CSF1,ATP1B3,CTBP1,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,CYP26A1,CDK14,RAD23A,ATP6V0B,GYS1,EGLN3,FAR1,SIRT1,TIMP2,TCEB2,S100A4,CDC20,DUOX1,RTN4RL1,ATP1A1,PSMD3,RPL22,AIFM3,ZNF701,COPG1,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TRAPPC10,CD63,ADGRG1,DAP,GNE,SWI5,PSMD10,NKRF,SIRPA,SLC9A2,PPP2R3A,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,FXR2,PELI3,AKAP3,FNDC3A,BCAR1,FUCA1,BANK1,TWSG1,NAT1,ZNF214,PGRMC1,PPP2R3C,SPCS3,NDFIP1,TBC1D4,UBE2C,DIS3L,CFAP74,ACVR1,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,CTGF,ZFP36,IL31RA,STEAP2,AOX1,TFG,RCAN3,XKR8,LAMP2,LOC81691,PBK,CASP9,TNS1,PIF1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TRAF5,LZTS1,DLAT,KLF2,CDK17,MRPL44,DGKQ,CALB2,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,MICB,AMER1,PIP4K2C,CYFIP2,KDM3A,RASA1,FAS,PRKAG2,CSNK1G1,NAB2,SLC4A3,TCEAL4,NRBP1,PKD1L2,IRF1,PLA2G4A,ELK4,S100A11,TRIP10,RPS6KA1,IQGAP1,CAST,SUZ12,RNF182,EGR3,NUDT12,GNB2,APLP2,FICD,DOK4,CDKN1B,TNPO2,DAB2IP,PHKA2,NR2C1,GPX4,SLC5A11,TEP1,PRKCQ,H2AFV,ZNF469,NIN,JAK1,STK26,KIAA1804,NRG1,RAB29,B4GALT3,ATMIN,DENND5B,OTUD5,ARHGEF3,SLC16A14,ARL4C,CDCA3,GPR180,APOBEC3H,TEAD3,SNTA1,OXCT1,MGAT1,PRC1,SGK3,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,SHMT1,CASK,MPP1,TEF,FURIN,VAMP3,C1GALT1C1,RGS9,PRDX3,SLC25A40,CSTF2,PGM2L1,SLC25A38,CPEB2,OCLN,NMRK1,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,PTCHD4,SH3KBP1,ABCD4,MAGOHB,LRRC6,IMPAD1,TSPAN6,PHTF1,KIF22,SUN3,RAB20,NFU1,MYH14,PTPRE,TRIM8,ASCL5,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,IARS2,RAP1GAP,PPP2R5D,CPPED1,PIFO,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,DIAPH2-AS1,EBF4,HP1BP3,PARD3B,GYLTL1B,HMG20B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,PLPP3,NFKBIA,CDCA5,RHOBTB2,ALPK3,YOD1,KIF12,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SLC25A48,SS18,KCTD15,ZDHHC12,FRYL,SMO,GOT1,STEAP3,RPN2,APIP,F2R,LOXL1,SCYL3,FRS3,MAP3K3,GCA,ZNF525,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CDS2,SORT1,JKAMP,FRMD6,TRMT2B,GALNS,CKS1B,BRD7,RAB3B,CENPC,MBNL3,OGDHL,SPAG1,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,ZNF596,SNPH,IBTK,AK7,GRIK2,SLC25A13,RET,TRAPPC8,BAIAP3,SNX9,LTBP3,CARD10,ZNF275,CDKN2C,NPM2,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,TIPARP,TIAM1,MGAT5,DSTN,CDA,PRKAR2B,RNF19B,GINS4,ARF4,PLCG1,CARHSP1,ENPP1,ATP7B,CELF5,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,RIMS3,MEGF8,ATP5H,RANBP1,FBXO7,PCYOX1,CADPS2,USP38,SLAIN2,MYDGF,ALPK1,MYLIP,ULBP2,DGKG,PHKG2,PAQR7,HPS3,PQLC3,MAPKAPK3,SHARPIN,ERO1A,KIF20B,SFXN5,GNA11,PSMA4,IL1R1,FNTA,CLMN,STK39,CFAP20,CBX5,NUP58,RUSC1,DOCK9,NQO1,LFNG,CD82,INPP5D,PTTG1,APOO,GRK6,MVB12B,MOCS1,CDH1,SH3BP1,XYLT2,RASGEF1A,DLG3,ETV4,SNX10,MX1,COL6A2,SEC61B,PFKFB2,SAT1,GIGYF1,EBF2,COX20,GABARAPL1,ALDH3B1,CCNB3,PNPLA6,MAPK12,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,SLC25A45,ZFX,PDCD10,ITGB8,FUT2,KNDC1,CST3,FAM20B,RAG1,PARP9,ADAMTS2,OPLAH,PLSCR1,UBE2A,AK4,RPL12,PROM1,LDLRAP1,PLOD2,DBI,NR4A3,PPM1H,OSER1,SSNA1,ITGAV,OSR1,CMPK2,CD81,PHC1,LMCD1,DNAJB11,TEX2,ITPR2,SPTB,FANCI,TFAP2E,CPNE2,CTNNB1,NPNT,ARL1,IL6ST,PASK,MITF,SLC44A1,PAPSS1,PSMC2,SCARA3,THRB,PLK1,KCNIP3,CELSR2,CCBL2,EAF2,SESN1,KDM4D,TNS4,HS6ST1,KLF12,AGPAT2,ZNF367,KPNA2,MYL12B,TC2N,RRAGD,HS6ST3,HJURP,LGALS3,DNAJB2,SLC22A31,PDCL,ADCK5,SORBS3,HES2,RAB6A,FBLN1,ANO1,UBE2Q2,WNT3A,CKAP4,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,NMT2,RASGRP2,FOXD2,FA2H,SLC2A6,P4HA3,ZDHHC7,RAD21,CTDSPL,TP53,P2RX7,BAHD1,EMP2,STIL,SYTL2,TMSB15B,PDGFA,TTC21B,PPME1,ESPN,TMEM64,NOTCH3,LMAN1,ERLEC1,SERTAD3,DAG1,TAPBP,PTGS2,RBL1,ABHD12,STK38,EFNA5,ARHGAP4,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,NRP2,FZD6,IL22RA1,M6PR,CD109,ALPP,CDK16,TFAP2A,GTF2F2,TRIM21,SGK1,HMGCL,SYK,P2RX4,HES1,HMGN5,PLAUR,STMN3,MAML2,BBS2,RNPEP,TXNDC11,DGKE,BCL10,USP6,CNOT2,DDAH1,FGF18,E2F1,ICOSLG,ARHGEF9,GOLGB1,ARHGEF4,LAMP1,TSC22D3,CUL1,PDGFRL,NANS,OAT,SEPT4,CYP1A1,ZNF823,PIK3CA,POLL,TACSTD2,MARCH2,ZBTB18,METAP2,ACVR1C,CDYL,POR,RAB2B,PRIM1,PPP2R4,PRDM5,MAPK13,SEMA6B,MRC2,THEMIS2,DHPS,PRKAA1,AKAP17A,APBA1,HERC6,S100A2,TNFRSF19,TSPAN7,PDXDC1,MESDC2,CALR,RALGPS2,ZNRF2,VASN,RPL39,TPST1,DAPK1,KCTD3,ZNF117,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,JADE2,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAM64A,FAAH,PELI2,MATN2,ZDHHC20,WDR19,ARAP1,FAM83D,MPP2,CABIN1,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,REPS2,TCTN2,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,FTH1,BLCAP,BCL2L1,DDR1,FLT3,ART5,EPS8L2,ZFYVE9,CD46,RALB,EPHB4,RNASEH2A,TSPAN1,FLOT2,COG2,FOXJ2,RAD17,ITPR3,ALCAM,ATP10D,ZMPSTE24,DDOST,TSPAN18,AREL1,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,SLC41A1,PBX3,CBLL1,NES,DNAH3,ADGRB2,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,PAPD7,TCFL5,FBXO9,YES1,FOS,CDK5RAP1,CRTC2,TIMP3,ABCB1,FZD5,MELK,UGT8,COMMD5,SLC8B1,ERP29,MAP1LC3B,ECI1,HTR1D,ADPRHL1,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,CERS2,USP18,ARHGDIB,GPRC5B,MADD,TDRD7,CAB39,GLA,CHPT1,CAPN1,NR2C2,PPP1R12A,ASB9,TEC,QSOX2,SPP1,B3GALNT1,TYW3,FAM20C,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,PODXL2,ELK3,VWA1,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,JAK3,SHROOM2,COL16A1,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,SEPHS1,EBAG9,UPF3A,PTPRU,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,CIT,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,ITGA2B,HMGXB4,HDAC9,SYDE2,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,SLC35A1,RPGR,RBMS2,B3GALT6,WNT10B,CFAP46,NADK2,RUNX3,TCEAL8,NDRG3,FOXL1,CD8A,SWAP70,RND3,CTSV,CSGALNACT1,SLC18B1,MCUR1,PLOD3,CEP41,AHR,CD33,ABCG1,DOC2A,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,IL18,LGI3,KIF26A,CA8,TP73,CALM2,WEE1,RGS12,PSMD1,ARHGAP42,PQLC2,DNAH6,ALDH1A3,TUBG1,TINAGL1,PIK3CD,ACOX2,APOBEC3G,ERAP2,SMARCA2,VPS11,SPRTN,LOXL2,ICMT,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,E2F8,GAB1,HOXC13,NFKBIE,NUAK1,CYP2J2,ZNRF3,MERTK,RAVER2,ELF3,GNS,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,OSMR,DYSF,MDH1,ARPC2,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,TUBB4B,GALNT12,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,PXYLP1,IRS2,SIPA1L1,INPP4B,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,KCNC4,GSTP1,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,CALD1,FDXR,ADAM15,ECI2,WWP1,MAPK11,SGCB,S100A6,CRTAP,AMOTL2,CTNNAL1,FMN1,BCL9,GRIN1,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,HMGA1,NUP37,USF2,FOXA1,MYL9,SIGIRR,CUL4B,SUDS3,NDC80,MCCC1,CDIPT,PIGL,SDC1,PCNA,CNTRL,LMAN2L,DUSP10,TNFRSF18,TLN2,MYBL1,S100A13,ZNF462,CD55,ING1,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,CDK1,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,BMF,RACGAP1,CNTNAP2,B4GALT4,DHRS3,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,PAK2,PSMA5,ABCC1,CYP26B1,CHSY3,MRPS33,TCF7,IFIT3,SMN1,MAPKAPK2,PVRL2,MFSD2A,ITGA7,PRPS2,LTBP2,TMEM120A,IFI6,NIPA1,RNF146,UPF3B,FOXM1,P3H2,XYLT1,ZNF28,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,PLCG2,LHX6,SRR,MINPP1,SCN2A,GM2A,DVL2,CTH,CPD,EVA1A,MBP,FIGNL1,MYL12A,MYPOP,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,POMGNT2,NDST3,CNEP1R1,GSDMD,MFSD14B,MACC1,BLVRB,SELL,GABRG2,JAG2,CRABP2,DSE,GBX2,SLC35B4,ABCD1,KLF9,TLE6,FAH,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,BORA,MAPK8IP1,SCRN2,PRDX4,CD83,FAT4,SERPINA1,CDCA7L,NMI,PKD2,ACADM,SAT2,SUN1,GAA,TAP1,GATA3,PLA2G16,FAM101B,CENPN,NCS1,CHST2,ELMO2,ATRNL1,PACSIN1,ORAI2,KIFC2,MGAM,AGO4,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,NDUFA4,ISYNA1,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,SORL1,TNFRSF12A,CD70,RIMS2,TSPAN33,FADS2,QSOX1,B9D2,PTPRH,ANO6,PKM,FBXO10,STX3,FRMD4B,DGKH,GABRD,SERTAD2,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,NLRX1,KCTD12,CD274,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,MYO5B,CDKN2AIP,SEC23A,TMEM43,CAPN6,DMTN,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,FYN,ZNF641,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,MLKL,HS3ST3B1,ZC3H12B,NR3C2,MRPS9,WASF3,ATP9A,CYB561,SEPP1,SPR,LGALS3BP,SIX4,RND1,FAM111A,PPP1R10,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,TRIM62,NCOA2,SMC4,RASGRF1,ARAP2,PARP4,GPLD1,CTNS,SERPINB5,GRIN2D,GPER1,ARSB,NCAPG2,USP16,JARID2,EXPH5,EMX1,CASP3,LTBP1,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,GRHL1,ZCCHC12,DPYSL2,DLG1,CAPG,AKR1B1,RP2,ARNT2,SLC39A10,TECR,RASGRP1,OLFML2A,ATL1,TDP1,SOD1,STRIP2,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,NEIL1,FASTKD1,ADIPOR1,APBA2,PSMC1,GRN,FAM213B,ELOVL7,ATP6V1E2,ZNF432,CA2,LRRN2,FXYD5,FNIP1,ZNF692,KNTC1,RFX5,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,AMDHD1,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,PITPNA,EGFL7,FBXW5,KLF7,GAS2L1,SLC25A24,IL15,PSME2,SLC2A8,GMPR,MICALL2,PATL2,SVBP,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,DUSP4,SNAPC2,KCTD2,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CYP2U1,PLXND1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,MXD3,IQGAP3,SYPL1,SUN2,ADAM17,GCLC,NR4A1,DEPDC4,ASPM,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,MARC1,HNRNPH2,DHRS2,TADA2B,UBE2D2,HOXB13,GEM |
| 3.955e-05 | -10.14 | negative regulation of protein serine/threonine kinase activity | biological process | GO:0071901 | 119 | 35 | 16441 | 2455 |
CASP3,SPRED1,CDKN1C,GSTP1,DUSP5,TP73,TFAP4,CDKN2C,PTEN,BMP7,RGS3,FBXO7,DUSP10,H2AFY,SORL1,CDKN1B,DAB2IP,HEXIM2,CDKN2D,SPRY2,DUSP1,PLK1,SIRT1,PRKAR2B,DUSP4,CDK5RAP1,PRKAG2,PTPRJ,STK38,RGS14,UBE2C,HSPB1,HIPK3,PKIA,PRKAR1A |
| 3.976e-05 | -10.13 | GSE12366_GC_VS_NAIVE_BCELL_UP | MSigDB lists | GSE12366_GC_VS_NAIVE_BCELL_UP | 181 | 47 | 17758 | 2588 |
CASP3,SOX9,BIK,LMCD1,PSMD10,GMCL1,HMGN3,MGST2,PSIP1,KCTD9,CKAP5,PCNA,BCL6,KIF22,KANK2,AK3,CTTN,PXMP4,NDUFA12,HSPA2,MPHOSPH9,PLK1,GFPT1,TDP1,SEC61B,DENND1B,PANK1,SYNE2,WHSC1,VEZT,ASB13,BCAR3,CDCA4,PRDX3,MAP2,CDCA5,NR4A3,KPNA2,CENPE,NCAPG2,UBE2C,CCNB2,CD81,ARHGEF9,ESPL1,SNX30,RAD21 |
| 3.976e-05 | -10.13 | TGFB_UP.V1_DN | MSigDB lists | TGFB_UP.V1_DN | 181 | 47 | 17758 | 2588 |
DDX58,NUDT6,UGT8,AVPI1,ZNF395,LGR4,HSPG2,GNE,GATA3,OSR2,SEPT4,HSF2,PAQR5,MITF,POLL,TFAP2A,FBXL14,BCL6,ATRNL1,CDKN1B,PLEKHF1,IFIT1,MINPP1,CITED2,MYBL1,SPRY2,SLC35A1,RIMS2,FRS3,TMCC2,RASGRF1,BAG4,PCBP3,SYBU,PTGER4,RAB38,DUSP4,SAV1,IFIT3,PRX,FRMD4B,AP1AR,SERTAD2,RBM47,RAB11FIP2,OTUB2,IRF1 |
| 3.976e-05 | -10.13 | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP | MSigDB lists | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP | 181 | 47 | 17758 | 2588 |
SORT1,PINK1,HSP90B1,SPC25,TMEM184B,IGFBP6,CDKN1C,ZCCHC24,DNAJC3,ITGA6,PTTG1,CDCA3,PLA2G16,SDC1,PPP2R3A,PDIA4,TOP2A,CCNA2,RRBP1,MITF,NEK2,MANF,FAR2,LMAN1,ALDH3A2,KDELR1,CTH,SSH3,TIMP2,SEC61B,PSRC1,KIF20A,CTNNAL1,CDC20,C3orf52,CBX6,KDELR3,PRKAR2B,SLC17A5,AURKB,CDK1,OPTN,DOLPP1,CSTF2,UBE2C,CCNB2,MELK |
| 3.985e-05 | -10.13 | FRASOR_RESPONSE_TO_ESTRADIOL_DN | MSigDB lists | FRASOR_RESPONSE_TO_ESTRADIOL_DN | 80 | 26 | 17758 | 2588 |
ANXA3,MMD,NDRG1,GNE,BIK,LITAF,ASB9,CBX6,ERBB2,COL4A5,DUSP4,LHFPL2,IER3,IL1R1,GNS,RND3,PLK2,MATN2,ARNT2,EFNA1,ERBB3,TTC9,RAP1GAP,SLC16A5,DUSP1,ABCG1 |
| 3.991e-05 | -10.13 | flotillin complex | cellular component | GO:0016600 | 9 | 7 | 17570 | 2579 |
CTNNB1,CDH1,CBL,FLOT2,CORO1C,LRP4,FLOT1 |
| 4.017e-05 | -10.12 | GSE2706_UNSTIM_VS_8H_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_R848_DC_UP | 176 | 46 | 17758 | 2588 |
MAN2B2,SIGIRR,AVPI1,HSPG2,ZCCHC24,BLVRB,XYLT1,NUCB2,ERP29,MNS1,FAM20C,SLC16A6,SIVA1,FDXR,FXYD5,IL17RA,ALDH7A1,TPCN1,CRTAP,CYP1B1,DDB2,MBP,PSRC1,SLC35C1,PYGL,PDK3,ESYT1,PTGFRN,SCRN2,MAGED2,NUDT16,DUOX1,TRAM2,TRIM47,PEX5,STX10,SH2D3C,WFS1,P4HA2,CDCA7L,CLMN,PIK3C2B,PLD1,FHL1,MAP3K5,CBX7 |
| 4.055e-05 | -10.11 | spindle pole | cellular component | GO:0000922 | 121 | 35 | 17570 | 2579 |
DLGAP5,CKAP2,POC1B,CALM3,CCNB1,SPDL1,CKAP5,CALM2,FRY,CTNNB1,TUBGCP6,PRC1,NEK2,TUBG1,KNTC1,PLK1,PSRC1,CEP89,ASPM,CALM1,CDC20,VPS4B,CKAP2L,KIF20B,AURKB,KIF11,NIN,PLEKHG6,FAM83D,FAM110C,AURKA,RGS14,WDR62,NDE1,SGOL1 |
| 4.125e-05 | -10.10 | RhoGEF | smart domains | SM00325 | 66 | 24 | 9131 | 1455 |
PLEKHG3,RASGRF1,ARHGEF28,ARHGEF3,FARP1,ARHGEF11,ARHGEF7,SPATA13,ARHGEF16,ARHGEF26,ABR,ARHGEF10L,PLEKHG6,ARHGEF19,ARHGEF37,MCF2L,PLEKHG1,FGD6,TIAM1,ARHGEF9,NGEF,ARHGEF4,FGD1,FARP2 |
| 4.130e-05 | -10.09 | Cyclin_C | pfam domains | PF02984 | 17 | 10 | 16629 | 2504 |
CCNE2,CCND1,CCNA2,CCNB3,CCNO,CCNJL,CCNL1,CCNB1,CCNF,CCNB2 |
| 4.134e-05 | -10.09 | cellular response to oxygen-containing compound | biological process | GO:1901701 | 928 | 182 | 16441 | 2455 |
SSH1,RET,NRG2,PSME1,IL18,ITPR2,CCNB1,HDAC6,PDGFB,SPTB,CALM2,PSMD1,RPS6KA2,CTNNB1,SHC3,PSMC2,KLF3,PIK3CA,DNM2,AKR1B1,RASGRP1,CYP1B1,SOD1,CASP9,EZR,PRKAR2B,POR,RHEB,ENPP1,TBX1,NOD2,CAB39,EIF4EBP2,PSMC1,GAB1,RRAGD,PRKAA2,KLF2,RASA2,SOX9,PRKAA1,PSMD7,ATP6V1E2,CALM3,DUSP5,TFAP4,IGF1R,COL6A1,PRKCI,PIM1,NCAM1,WNT3A,MAPK7,PSMA5,OXR1,CALM1,STRADB,CALCRL,PDK3,ELK1,PSMA4,RHOB,EGFR,RASA1,GNAS,FECH,IL1R1,TSC1,NCOA3,PRKAG2,INSR,NFKBIA,SH3BP4,RAB31,DGAT2,NR4A2,MAP3K5,JAK3,COL16A1,RARG,DRD1,SPRED1,SORBS1,SLC2A4,NQO1,IL15,SLC2A8,PSME2,SOD2,WDTC1,ERBB2,RASGRP3,BCL2L1,PRKACA,GNB2,PDGFA,ATP6V0B,CDH1,SMO,DAB2IP,GOT1,PDE4D,OSBPL7,RASGEF1A,FRS3,SIRT1,PPIF,RIPK2,AKT1,FZD4,DMTN,CD40,CASP4,FZD7,SOCS3,IRS2,PTGS2,FYN,IDE,JAK1,CDK19,AXL,PTK7,PSMD3,STAT1,NRG1,SPTBN5,ABCA1,PRKAR1A,HSP90B1,PLSCR4,CPEB4,TRAF2,PSMD10,ETS1,GSTP1,FGF19,ICAM1,HDAC9,CAPN2,CXCL16,PDCD10,IRAK1,CST3,KLF9,ERBB3,GFI1,CAMK2G,MYO5A,HCN3,P2RX4,PDGFC,RASGRF1,ADAM17,SHMT1,PSMB4,WNT10B,RAPGEF2,NR4A1,PIK3R1,GRIN1,LITAF,YES1,FOS,BCAR1,GPLD1,FGFR2,RAB11FIP2,PRDX3,FGF18,NR4A3,E2F1,OSER1,GRIN2D,PKD2,GPER1,CMPK2,ATP6V1C1,OSR1,TBC1D4,CPEB2,PHC1 |
| 4.161e-05 | -10.09 | ALFANO_MYC_TARGETS | MSigDB lists | ALFANO_MYC_TARGETS | 233 | 57 | 17758 | 2588 |
CCNI,LTBP1,LASP1,KIF3C,AGRN,CDKN1C,GNPDA1,ATP8A1,ITGA6,SOX9,SDC4,MMADHC,PDIA5,FLOT1,AES,KCTD12,SLC20A1,SDC1,PHLDA1,TFAP4,ADD3,OXCT1,CYR61,TACC2,KCNN4,PLK4,ATP8B1,CTH,PPIF,QSOX1,DDB2,TIMP2,PLAUR,RAPGEF2,CRIP2,MYBL2,AK4,RUNX3,EPHA1,NPC2,ATP1B1,ASB13,CLCN2,MYL12A,VCP,MAP1B,FYN,PEX5,PAFAH1B3,ITGA7,MMP17,MYLK,CTNND1,RAP1GAP,AFAP1,IRF1,EHD1 |
| 4.192e-05 | -10.08 | regulation of microtubule cytoskeleton organization | biological process | GO:0070507 | 124 | 36 | 16441 | 2455 |
GAS2L1,CKAP2,RACGAP1,CCNB1,HDAC6,APC2,CTNNB1,CENPJ,TUBGCP6,TBCD,NEK2,PLK4,CDKN1B,DIXDC1,SLAIN2,WNT3A,PLK1,CAMSAP3,RHOA,PSRC1,VPS4B,STMN3,AURKB,CCNF,BORA,KIF11,NUBP1,SKA1,CDK5R1,MID1IP1,PLK2,AURKA,EFNA5,CHMP4B,XRCC3,GEN1 |
| 4.209e-05 | -10.08 | Integrated Cancer pathway | WikiPathways | WP1971 | 35 | 16 | 4455 | 729 |
PLK1,CASP3,AKT1,CASP9,TP53,BARD1,CDK1,RB1,JAK1,NOXA1,PTEN,MSH2,STAT1,BAX,E2F1,MSH6 |
| 4.270e-05 | -10.06 | regulation of protein dephosphorylation | biological process | GO:0035304 | 148 | 41 | 16441 | 2455 |
SPRED1,PINK1,FARP1,LMTK3,PPP4R4,HSP90B1,PPP1R2,PPP1R12A,NUAK1,CALM3,TIPRL,SH2D4A,PPP2R3A,SYTL2,SH3RF2,CALM2,BMP2,ADORA1,NPNT,PPME1,CRY2,DLG3,SLC39A10,PPP6R1,CHP1,CAMSAP3,BAG4,CALM1,CDCA2,PKMYT1,GPLD1,TSC1,SWAP70,PPP2R5A,HTT,SEMA4D,PPP2R4,CNEP1R1,PPP2R2D,PPP2R5D,ARFGEF3 |
| 4.295e-05 | -10.06 | HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES | MSigDB lists | HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES | 228 | 56 | 17758 | 2588 |
RECQL,PEX6,RALBP1,GNAL,ARL4C,SMARCAL1,ABCG2,DHX8,MRAS,RAB6A,SEPT4,GNB2,PICK1,ABCD4,TOP2A,DIRAS3,RAC2,ENTPD4,ARL1,MSH2,ABCA2,ATP8B1,RAB27B,ARL4D,MSH6,ATP2B1,ABCC1,RAB3B,RHOA,VPS4B,KIF20B,ARFRP1,PIF1,ATP1B1,GNA11,RHEB,VCP,RHOB,ARF4,DDX23,GNAS,TAPBP,ENPP1,ATP1A1,ACYP1,DNM1L,RND3,DOLPP1,ATP7B,PPP2R4,RAB31,ATP1B3,ATP6V1C1,ARF6,PSMC1,ABCG1 |
| 4.384e-05 | -10.03 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 197 | 50 | 17758 | 2588 |
GCLM,GOLIM4,IL15RA,LGALS3,IL15,CHCHD7,GCAT,SERPINB9,GATA3,ASAH1,PBX3,KCTD12,NCKAP1,IL18R1,ECI1,SLC35E4,SSX2IP,IER3,CAPN2,DAPK2,CD22,AIM1,CAPG,MDFIC,OSTF1,TMEM37,F2R,ITM2C,SNX10,IL10RB,S100A13,RPGR,S100A6,POU6F1,PQLC3,PLSCR1,S100A4,DSTN,LPGAT1,LITAF,GGH,DOCK5,CASP4,ENPP1,ABCB1,SERPINB6,TMEM159,CHPT1,ACOT7,MAPK12 |
| 4.384e-05 | -10.03 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP | 197 | 50 | 17758 | 2588 |
PLA2G4A,ANXA3,JKAMP,HEBP1,FAM129B,KCTD12,FAM91A1,FAM101B,IL18R1,SIRPA,IER3,CCND1,SLC25A45,CA2,GATA2,MITF,PCYOX1,TMEM51,SORL1,FAM102A,DAB2IP,C10orf54,PTPRE,TTPA,CASD1,IL10RB,C9orf72,ABCC1,SOCS5,ADAM17,HPS3,STAU2,S100A4,LITAF,DOCK5,ENDOD1,FYN,HLF,LDLRAP1,SWAP70,PRCP,PLA2G15,APPL2,TDRD7,RAB31,ARRB1,LRRK1,GEM,CD81,CD33 |
| 4.409e-05 | -10.03 | Thioredoxin_domain | interpro domains | IPR013766 | 31 | 14 | 18293 | 2672 |
QSOX1,DNAJC10,TXN,P4HB,TMX4,PDIA5,PDIA3,TXNDC9,ERP44,PDIA6,TXNDC11,QSOX2,TMX1,PDIA4 |
| 4.441e-05 | -10.02 | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | MSigDB lists | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | 464 | 99 | 17758 | 2588 |
MTM1,LZTFL1,ST13,TTC39B,TSC22D3,SLC25A13,XIAP,PKP2,KCTD12,FAM101B,CA8,CACNB4,FAM46C,CARD10,TMC1,GNB2,SYTL2,DAPK2,RPS6KA2,CDH1,TACC2,SMO,TNPO2,KIF22,F2R,CPD,GCA,TMEM43,SAT1,SESN1,RNF19B,SP4,EBF2,VCP,ATP13A2,SOCS3,PTGS2,PTPRJ,WWTR1,TLE1,RELL1,ARF6,SGOL1,NRGN,F2RL1,ATMIN,OTUD5,GALK1,FBLIM1,RUNX2,SH3D19,EPS8,NUCB2,DHRS3,MERTK,AIP,FZD6,B4GALNT1,WDFY1,PFKL,KCNN4,RANBP1,SORL1,SGK1,MDFIC,CTSD,SGCB,MYO5A,UFD1L,PRSS23,PLSCR1,STAT4,PLAUR,TCF7,YES1,PDK3,FOS,SKA1,KIF11,FRMD4B,SOX13,GALNT3,PTPRF,ARHGAP24,ENDOD1,NR1D2,SYT7,RCBTB2,TMEM30A,CDCA5,ABCB1,SH3BGRL2,FHL1,LRRK1,GEM,ICOSLG,SERPINB1,AHR,RAB3IL1 |
| 4.443e-05 | -10.02 | PROTEIN_AMINO_ACID_PHOSPHORYLATION | MSigDB lists | PROTEIN_AMINO_ACID_PHOSPHORYLATION | 276 | 65 | 17758 | 2588 |
TNK1,ACVR1,NF2,RET,ERBB2,TESK2,MAPK4,PICK1,CCND1,DAPK2,CDKL5,IL31RA,PLK4,F2R,MAP3K3,NEK4,MARK1,AKT1,MAP3K6,STK17B,LIMK1,STK38,MYLK,KIAA1804,STAT1,MAP3K11,MAPK12,PRKAA2,PINK1,DYRK3,CDK17,PRKAA1,TGFBR1,TRIB2,PKN1,MERTK,IGF1R,CDK16,PAK2,MAP3K9,DAPK1,PRKG1,PRKCI,SGK3,SGK1,PIM1,ERBB3,CCDC88A,STRADB,EIF2AK1,ILK,EGFR,STK17A,TXK,PRDX4,MAPKAPK2,INSR,ACVRL1,NR4A3,AURKA,JAK3,CD81,HIPK3,CTBP1,DMPK |
| 4.443e-05 | -10.02 | TATTATA,MIR-374 | MSigDB lists | TATTATA,MIR-374 | 276 | 65 | 17758 | 2588 |
CCNE2,LTBP1,FAF2,IL15RA,GATA3,TRAPPC8,CCNL1,GNB2,CHST2,FOSB,PDE4D,RAB38,ANLN,SP4,ABR,NFIX,DZIP1L,BOLA3,HLF,ATP1A1,WDR11,MAP2,NFKBIZ,STARD13,CBX4,ATMIN,SCN5A,RUNX2,CPEB4,NUAK1,BACE1,ZCCHC24,ETV5,ARHGEF40,TEAD3,NEO1,GBX2,TFAP4,BMP2,MGAT4A,OCRL,FNIP1,PIKFYVE,PPP6R1,SPRY2,MOB4,CYP26B1,HES1,PMPCB,DCAF6,LCA5,KIF20A,NR3C1,SYBU,C3orf58,BSDC1,CRTC2,PITX2,BANK1,SERTAD2,FGFR2,NR4A3,CLIP4,NR4A2,PKIA |
| 4.461e-05 | -10.02 | V$AP1_C | MSigDB lists | V$AP1_C | 260 | 62 | 17758 | 2588 |
SPRED1,CMAS,LRRFIP2,CAPN12,NUAK1,CALB2,XYLT1,ETV5,FBXO2,MPP5,FAM81A,SEPT4,PRR7,LTBP3,ZNF385B,LMNA,ZFYVE9,BTG3,VASP,PSMD1,IRAK1,SHC3,NECAB3,SLC16A6,ADAM15,VAT1,ABCD1,NTN4,SNX10,HCN3,TUBA4A,MDFI,SEMA3B,SMARCA2,ARAP2,MLEC,MARK1,CAPN6,PHLDB3,TCF7,COL7A1,EPHA1,ATP1B1,C15orf39,KDM3A,ZFAND5,TYSND1,PRX,GABARAPL1,TBC1D17,TMEM54,MAP2,S100A5,SERPINB5,FBXO44,RCAN2,EFNA1,REEP4,RTN3,TOB1,COL16A1,MAMDC2 |
| 4.469e-05 | -10.02 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 192 | 49 | 17758 | 2588 |
RMND5A,NDRG1,FRMD6,DAP,DGKA,KIF23,C6orf106,MGST2,FAM101B,LGALS3BP,TOP2A,RPS6KA2,RALGPS2,IL6ST,TSPAN13,CNGA1,STT3B,MINPP1,RCAN3,CDKN2D,PSMA5,SMC4,EPHX1,MX1,CXXC5,PLAUR,MPP1,CBX6,EZR,PDK3,RAB3IP,SESN1,CYB5A,RASGRP2,NFIX,CD8A,TMEM50B,ATP1A1,PPP2R5A,ACVRL1,TWSG1,PRPS2,NAB2,UBE2D2,NR4A3,NFKBIZ,IRF7,ST3GAL1,EHD1 |
| 4.469e-05 | -10.02 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN | 192 | 49 | 17758 | 2588 |
GCLM,DLGAP5,HJURP,ETNK1,RACGAP1,IL13RA1,KIF2C,CCNB1,PHLDA1,FANCI,CKAP5,IER3,TOP2A,TNS3,TYMP,BDH1,RANBP1,DAPK1,CKS1B,TUBG1,RNASEH2A,FAH,CKS2,LAMP3,HMMR,SHMT1,ALDH2,ZWINT,CENPA,HN1L,KIF20A,ASPM,UBE2A,AURKB,IDH1,KIF11,PRIM1,LRRC42,IL1R1,SLCO4A1,CSTF2,AURKA,KPNA2,NUP37,NCAPG2,CCNB2,ESPL1,ACOT7,MELK |
| 4.476e-05 | -10.01 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological process | GO:0031657 | 9 | 7 | 16441 | 2455 |
PKD2,ADAM17,PIM1,AKT1,PTEN,EGFR,RGCC |
| 4.477e-05 | -10.01 | cervix | COSMIC cancer mutations | cervix | 12381 | 1885 | 17775 | 2585 |
HECA,FAM160B1,IBTK,AK7,SLC25A13,HEXB,RET,MCOLN3,CCNO,TRAPPC8,TGOLN2,BAIAP3,DPP8,SNX9,SPSB1,CARD10,LTBP3,ZNF275,GRM5,LYPD5,CDKN2C,NPM2,PHYHIP,MUC4,UBE2T,DNM2,CRY2,PPP1CA,TMEM37,RNF26,WBP4,TIAM1,CPE,TIPARP,MGAT5,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,DSTN,TMEM98,KDELR3,TMEM151A,TFAP2C,RNF19B,PNKD,ABR,ARF4,PIAS3,ENPP1,PLCG1,ATP7B,CELF5,FAM114A1,TRAF3IP1,NOD2,TMOD2,RNASEL,ITPKA,STARD13,HSPB1,ANXA11,ZNF720,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,CCDC64B,FAM21C,HPCAL4,RABGGTA,FLII,SH3D21,RAC2,ZCCHC17,FRY,PAIP2B,ATP5H,MEGF8,FBXL14,PCYOX1,MAP3K9,CADPS2,USP1,USP38,FAM84B,ALPK1,PANX2,CNGA1,MAPK7,ZMYM1,DGKG,ULBP2,KANK3,NUP85,PPP6R1,TTLL1,HPS3,PQLC3,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,SFXN5,GNA11,PLIN5,MAGED2,IL1R1,CACHD1,FNTA,SLC4A4,ETS2,RAET1L,DGAT2,CLMN,GDF11,RUSC1,ADAMTS16,DMPK,DOCK9,WDR63,TPRN,NQO1,LFNG,RHBDL3,FAM91A1,MOCS1,REPS1,APPBP2,RBM23,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,TMCC2,MX1,SNX8,SEC61B,COL6A2,ERMP1,C6orf1,RIPK2,APOBEC3D,PFKFB2,AGPS,SEPT6,VPS4B,SYP,DNAJB14,TANC1,GTF2A2,ZNF618,TRIM7,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,FAM149A,DMWD,PRIMA1,SLC25A30,HSP90B1,MPZL1,FAM189A2,CKAP2,GCAT,ESRP1,BACE1,TRAF2,BIK,HABP4,CCM2,SDC4,OSGIN2,BTN3A1,CTSZ,ZNF219,PLPPR4,NFAT5,CTNNBIP1,DIRAS3,ZFX,FUT2,ITGB8,IGSF9,KNDC1,GPC3,MGAT4A,TMEM62,CST3,TUBGCP6,FAM20B,KLC3,ZFAND4,FAM102A,RAG1,CASD1,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,CXorf57,PGBD1,RAB3IP,CNTNAP1,PROM1,RPL12,RAB11FIP2,SYT7,SLC35B3,SSNA1,ITGAV,OSR1,CMPK2,ACOT7,SRSF9,PHC1,TLL2,TMEM131,ILDR1,TNK1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,PHOSPHO1,DNAJB11,TEX2,F11R,NENF,GALM,MGAT5B,ITPR2,SPTB,FANCI,TFAP2E,PLS3,SUSD2,INPP5E,ENTPD4,RPS6KA2,NUP210,CTNNB1,RABEP2,P4HB,IL6ST,PSMC2,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,SMAGP,PLK1,MARK1,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,CCBL2,CKAP2L,NKAIN1,TRUB1,DZIP1L,KDM4D,TRIM9,TNS4,PLEKHG6,TMEM164,KCNMB4,AGPAT2,ARRDC1,KPNA2,TTC39C,TC2N,PARP12,RUNX2,USH1C,HJURP,LGALS3,DNAJB2,RASA2,SORBS3,ADCK5,RAB6A,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,NTN1,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,RGMB,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,CDK5R1,PRX,NMT2,C18orf8,RASGRP2,FOXD2,FA2H,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,AKIP1,SEMA3A,CDAN1,USP43,RAD21,HOXB7,TMX4,TP53,RHPN2,P2RX7,BAHD1,PCBP1,PRR7,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,TACC2,PPME1,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,ERLEC1,AKT1,KIAA0040,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,ZNF628,TAPBP,IDE,PTPRJ,RBL1,STK38,MAOA,XRCC3,EFNA5,IRF7,SYT13,ARHGAP4,ST3GAL1,BIN1,ZMAT1,PINK1,CDH22,CPEB4,KLHL13,TAB3,CTSB,SCD5,GNAL,MCTP2,HAL,ERCC6L,ERI2,GTF3A,AIP,LBR,PARM1,IL22RA1,H1FX,NRP2,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,TFAP2A,GTF2F2,TRIM21,TSPAN13,CPLX1,HMGCL,SYK,ATP2B1,LRRC24,DUSP1,NFE2L3,P2RX4,HES1,FBLN5,RHOA,MOSPD2,HMGN5,GUSB,STMN3,PRICKLE1,DPP9,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,USP6,DDX23,CNOT2,SCG2,NEIL3,FGF18,E2F1,ICOSLG,PTGES,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,PNISR,LGR4,SSH1,HSPG2,TSC22D3,CUL1,PDGFRL,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,CYP1A1,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,TACSTD2,ARMCX6,ACVR1C,CDYL,SLC35C1,KIF13A,LDB2,RAB2B,PRIM1,ANKRD10,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,SERPINI1,SPRY4,CCDC97,FGD1,SEMA6B,RECQL,MRC2,SCOC,DHPS,TBC1D1,TMEM55B,AKAP17A,APBA1,PDXDC1,TSPAN7,PSIP1,SH3RF2,MESDC2,C9orf69,CALR,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,RPL39,AIM1,MSH2,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,C8orf58,CACNA1D,DLX4,KCTD3,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,SPATA20,GCC2,PRODH,KCNJ12,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,CALM1,DCHS1,PYGL,WHSC1,ATP8B3,ANTXR1,PDE11A,MMP15,NT5C2,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,PIAS2,FAM83D,MPP2,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,SAMD8,ZBTB34,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,GPR107,CAPN12,REPS2,ST14,CCDC110,THRA,DDIT4L,NDRG1,CERCAM,RALBP1,ATP2C2,BCL2L1,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPS8L2,C11orf84,CD46,APOBEC3B,CCNA2,ACAP2,TRANK1,EPHB4,OSBPL7,SULT2B1,FLOT2,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,CLSTN1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ITPR3,ASB13,ALCAM,ATP10D,FZD7,ZMPSTE24,AMZ2,DDOST,POPDC3,ACAD10,TRIOBP,SLC27A3,PRR15,CBX7,MAMDC2,PLSCR4,HAPLN3,SLC41A1,CENPI,EPS8,CBLL1,NES,HERC5,PBX3,PLD2,DNAH3,EFNB1,HLA-A,WWP2,SLC25A36,CKAP5,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,CCDC82,ERBB3,TTPA,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,ZC3H11A,PAPD7,TCFL5,ZKSCAN2,FBXO9,DIAPH2,UBAC1,YES1,GRTP1,FOS,KIF11,CDK5RAP1,CRTC2,DCTN6,ACADSB,DGCR2,SEC14L4,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR62,WDR91,FZD5,ESPL1,CXorf56,DEF6,MELK,FAF2,UGT8,UBE2Q1,VARS2,PLAC1,MPP5,ERP29,TRIM68,ECI1,HTR1D,ADPRHL1,ZFYVE16,SIPA1L2,HSF2,CDKL5,ARHGEF37,METTL7A,ANKFN1,CEP78,TRPC1,ASH2L,CTTN,MYRIP,IL1RAP,STK35,LAMP3,ASXL1,LAP3,ITCH,ACBD3,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,MADD,ZNF165,SP6,GLA,RBM43,CHPT1,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,ZNF395,PPP1R12A,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,QSOX2,SPP1,TYW3,B3GALNT1,CES2,NOXA1,PFKL,FAM20C,OCRL,COL6A1,MTMR10,PRKCI,SRP54,LIMCH1,BRAT1,C10orf54,NPTN,HLA-C,ZRANB1,GAD1,SLC12A2,CCDC88A,SNED1,TPGS2,ELK3,PODXL2,SPA17,PDE5A,KIAA1109,HEATR5A,NUBP1,C3orf58,RANBP9,RHPN1,SOX13,INSR,UAP1,TMEM30A,SPAG7,SH3BP4,RAB31,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,RARG,AFAP1,DRD1,LMO7,NCKAP5,DYNLRB1,PAX6,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,SAP130,ZNF687,CYP4F11,KIF14,ZBTB49,DIXDC1,EPB41L4B,ETHE1,NFKB2,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,CD40,TMTC2,CDC25C,PDHX,ARHGAP35,SOCS3,HSF4,ALDH5A1,STAT6,SECTM1,PTBP3,RCAN2,SPTBN5,MAD2L1BP,ABCA1,LNP1,GLIS3,GCLM,ENO2,TSPAN15,ARHGEF11,ARHGEF7,SHPRH,SH3D19,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,RBP7,XPR1,HMGXB4,ITGA2B,HDAC9,TMEM63A,SYDE2,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,TOX2,RRBP1,ZDHHC13,ARVCF,KANK2,CLIP2,SLC35A1,RPGR,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,RUNX3,FAM73B,NDRG3,LEPR,FOXL1,LEMD2,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,TRIM69,RAP2C,SPINT2,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,DOC2A,ACACB,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,XIAP,CACNA2D2,SMARCAL1,DHX8,NRG2,LGI3,SYTL4,CA8,BARD1,KIF26A,PHF1,EPDR1,CALM2,DAPK2,TP73,ZYX,TGFBR3,RGS12,AP1M2,PQLC2,ARHGAP42,KIAA1107,DNAH6,CYP2S1,CABP1,PPP1R16A,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,SERTAD4,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,TRIM47,CAMK2N2,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,LSM14B,ARF6,PDPR,GAB1,E2F8,ALDH6A1,TMTC3,CYP2J2,STRN4,ZNRF3,MERTK,LMNA,ELF3,GNS,DNPEP,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NEK2,NCAM1,EPHX1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,MEST,SPTLC2,DCP2,RHOB,STK17A,DHX32,PTPRF,SCARB2,NAAA,NCOA3,HTT,SETD3,TEX30,ITPR1,DYSF,AURKA,OSMR,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,TRPC3,ZNF502,RPS6KA3,CSRP2,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,FAM131C,ACTR8,WDTC1,RGS20,ETNK1,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,ZNF385B,UHRF1BP1L,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,SCN3A,ENPP4,CAMSAP3,SSH3,PSRC1,LGALS8,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,IRS2,PEX5,STX10,TTC12,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,PDXK,RGS14,ARNT,TTC8,GALK1,FARP1,TAOK2,NKX3-1,TNRC6C,PARP14,MAN1A2,RASSF7,PDIA3,GMCL1,ANO9,PKN1,GSTP1,ETS1,KCNC4,SRPX2,HOXB2,ICAM1,NEO1,PDIA4,CAPN2,DTX3L,CXCL16,ANK1,ADD3,IRAK1,SLC27A6,ANKS1B,FAM160A2,KCNK5,CALD1,ALG13,FDXR,ADAM15,ECI2,MAPK11,AK3,NPTXR,SGCB,ITM2C,TPCN1,TMX1,HCN3,AMOTL2,POU6F1,NUDT8,LCA5,CTNNAL1,FAM160A1,FMN1,RAPGEF2,MFSD2B,GRIN1,PLEKHA7,DBR1,MYEOV,EMP3,SNTB1,CRISPLD2,ABLIM2,TXK,PITX2,DCAF10,GALNT3,KIAA0141,ATXN7L3,ACVRL1,NR1D2,CCDC6,CENPE,FHL1,HMGA1,NUP37,SHOX2,MYL9,UNKL,SIGIRR,TRIM2,AGRN,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,SDC1,PCNA,SHC3,MKRN3,LMAN2L,ELF5,DDHD2,DUSP10,RGS5,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,HN1L,EZR,TNFAIP8L1,ERP44,ESYT1,FAM212B,IDH1,ZBTB7B,VCP,DPYSL3,PLCH1,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,GATA2,SPIN4,EXOC8,TMEM8A,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,WDR72,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,G2E3,EPN3,DHDH,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,CTBP1,RNF146,FAM45A,NF2,UGP2,UPF3B,FOXM1,XYLT1,DGKA,ZNF28,ERBB2,SLC7A2,CCNL1,FAM198B,LPIN3,C1orf116,CYP26A1,PER2,RAD23A,CDK14,ABRACL,ATP6V0B,SRPX,EFR3A,N4BP3,PLCG2,LHX6,SRR,GYS1,SCN2A,DVL2,GM2A,CPD,SIRT1,TMTC1,CDC20,MYL12A,MYPOP,DNAJC10,DUOX1,ATP1A1,PRRT4,RTN4RL1,PTK7,ADAMTS14,ANXA9,ZBTB6,C1orf43,AIFM3,NDST3,ZC3HC1,CMTM4,MAN2B2,COL9A3,PACSIN2,TRAPPC10,CD63,MACC1,RUSC2,GNE,GABRG2,SELL,PSMD10,NKRF,JAG2,DSE,PPP2R3A,SLC9A2,SIRPA,GBX2,CCDC92,CEP97,MAGEE1,ABCD1,BUB1,KLF9,HEXIM2,SLC45A3,TLE6,FAH,IGDCC4,DLGAP1,HMMR,MLEC,IFITM3,NR3C1,PPARA,CCDC34,TRIM35,CAPNS1,AKAP3,PELI3,FNDC3A,NPDC1,BCAR1,BSDC1,MAPK8IP1,SCRN2,TMEM50B,BANK1,SERPINA1,FAT4,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,FAM117A,PKD2,ACADM,TBC1D4,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,KLC2,TAP1,PPFIBP2,PLXNA1,PLA2G16,SLC20A1,ELMOD2,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,ATRNL1,MTMR11,RCAN3,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,GALNT7,MCFD2,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ULK2,SGPP1,AHRR,SFXN1,KDSR,FAM177A1,PTER,GNPTAB,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,RTN3,LZTS1,DLAT,DDX58,MRPL44,INPPL1,CDK17,FRMD4A,HLA-E,ADO,CALB2,DGKQ,KIF23,ISYNA1,SLC1A3,NOTCH2,BMP2K,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,BDH1,SORL1,CD70,TNFRSF12A,PIKFYVE,CTSD,RIMS2,EEF1D,DNAI1,FAM69A,DDB2,QSOX1,MFI2,KIAA1841,TBC1D8B,MICB,AMER1,PTPRH,ANO6,PIP4K2C,KCTD20,VEZT,FAM133B,PKM,KDM3A,FBXO10,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,DCK,NAB2,SLC4A3,FGD6,PCDH19,EFNA1,MAP3K5,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,ARMCX3,CEP70,TRIP10,NLRX1,BROX,CAST,SUZ12,IQGAP1,IRX4,RNF182,KCTD12,EGR3,CD274,SNN,NUDT12,MNS1,GNB2,SLC25A35,CYHR1,APLP2,ZNF75D,FAM46A,FICD,TNPO2,CNNM4,DAB2IP,PHKA2,NR2C1,TMBIM1,TBC1D10B,MYO5B,SLC5A11,CDKN2AIP,SEC23A,TMEM43,CAPN6,TEP1,SLC11A2,PRKCQ,C15orf39,AKR1E2,SP4,ZNF469,PRDM11,NIN,OSBPL2,EPHA10,FYN,PPP2R5A,JAK1,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,ZC3H12B,B4GALT3,NR3C2,ATMIN,DENND5B,OTUD5,MRPS9,WASF3,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,JRKL,ATP9A,CDCA3,CCNJL,GPR180,APOBEC3H,SPR,SIX4,LGALS3BP,TMCC3,RND1,SNTA1,C16orf59,FAM111A,PTEN,CENPJ,SGK3,PRC1,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,NCOA2,OSGIN1,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,TEF,MPP1,DENND1B,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,RGS9,MAMDC4,CTNS,PRDX3,RCBTB2,AMMECR1,SLC25A40,PGM2L1,CSTF2,GRIN2D,SLC25A38,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,CPT2,TAF6L,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,MAGOHB,GRHL1,ZCCHC12,DPYSL2,IMPAD1,PHTF1,DLG1,ANKRD12,AKR1B1,KIF22,RAB20,RP2,NFU1,ARNT2,MYH14,SLC39A10,RASGRP1,FGFR1OP2,OLFML2A,ATL1,TDP1,SYNE3,RNF165,ROR1,PTGFRN,ADRBK2,STK17B,TCN2,SEC14L2,EDNRA,MDK,LRRC42,ZNF114,ARHGEF19,FASTKD1,UEVLD,IARS2,TRIM45,CCDC74B,APBA2,RAP1GAP,PSMC1,PPP2R5D,MIIP,CPPED1,GRN,LRRFIP2,PEX6,ASL,ATP6V1E2,SAMD9,PHLPP1,LYSMD4,OTUD1,ZNF432,AIM1L,CA2,LRRN2,EBF4,FXYD5,ZNF692,KNTC1,RFX5,ACAD8,SIMC1,LRIF1,ALS2CL,KDELR1,HP1BP3,PARD3B,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,EGFR,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,TSC1,SLC6A6,UTP14C,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,KIF12,PROM2,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,ABCG4,MORC4,GMPR,TDRKH,ZMYND10,MICALL2,ARHGEF16,LRRC45,KCTD15,SETDB2,ZDHHC12,FRYL,SMO,TWIST1,APIP,PDIA6,F2R,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,BAG4,TAF5,SLC39A8,IGSF8,ERBB2IP,DUSP4,SNAPC2,KCTD2,DOCK5,BFSP1,BHLHB9,PEX2,CANT1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,PPP2R2D,LIFR,CBX4,CCDC24,ANXA3,CDS2,SORT1,FRMD6,POC1B,JKAMP,LRP4,FAM134A,MIER3,TRMT2B,POMGNT1,IL17RB,IRF2BPL,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,BRD7,HSPA13,IQGAP3,SYPL1,SUN2,ADAM17,DEPDC4,PHLDB3,ASPM,OGDHL,LRRC66,POLD3,SPAG1,MAP1B,KLHL2,HLA-B,PRCP,HNRNPH2,TADA2B,GLB1,GEM,L1CAM,SNPH,ZNF596 |
| 4.521e-05 | -10.00 | REACTOME_DEVELOPMENTAL_BIOLOGY | MSigDB lists | REACTOME_DEVELOPMENTAL_BIOLOGY | 380 | 84 | 17758 | 2588 |
MYL9,CCNC,SLC2A4,PAX6,AGRN,RPS6KA1,ERBB2,PLXNA1,CACNB4,SPTB,PAK6,RPS6KA2,ARTN,CTNNB1,DPYSL2,DLG1,DNM2,NTN4,MYH14,SCN2A,DLG3,MED30,COL6A2,AKT1,ACVR1C,DRAP1,EZR,PRKCQ,ALCAM,CDK1,DPYSL3,ARHGAP35,PLCG1,FYN,CDK19,LIMK1,KLF5,SPTBN5,PLXND1,UNC5B,MYL12B,MAPK12,SCN5A,COL9A3,ARHGEF11,COL4A5,NRP2,ITGA2B,RND1,NEO1,RAC2,ANK1,VASP,COL6A1,PAK2,MAPK11,NTN1,NCAM1,NCOA2,MED22,FARP2,DPYSL5,HES1,RHOA,WNT10B,RGMB,FURIN,PPARA,DPYSL4,RANBP9,EGFR,CDK5R1,RHOB,CNTNAP1,ONECUT1,NCOA3,SEMA4D,PITPNA,ITGAV,SEMA3A,TRPC3,L1CAM,RPS6KA3,RGMA |
| 4.546e-05 | -10.00 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | 187 | 48 | 17758 | 2588 |
CD99,BIN1,SLC35D2,ENO2,TUBB4B,DAP,CD82,BLVRB,FBXO2,NANS,BAIAP3,CAPN2,WEE1,MZT2A,KCNN4,DPYSL2,LMO4,BHLHE41,PLCG2,PAPSS1,CAPG,UBE2J1,FAM102A,CD70,FAIM,ITM2C,RASGRP1,TMBIM1,S100A6,SMAGP,SEC61B,GCLC,DENND1B,S100A4,CRIP2,SYBU,SGPP1,ATP1A1,PRDX3,AGBL5,RAB31,CSGALNACT1,CAB39,CTSA,GRAMD1C,ZMIZ1,TMEM14A,EHD1 |
| 4.553e-05 | -10.00 | synapse | cellular component | GO:0045202 | 679 | 137 | 17570 | 2579 |
DOC2A,LAMP1,AGRN,GRIK2,EPHA4,FBXO2,LGI3,PJA2,CACNB4,PICK1,GRM5,NCS1,SH3KBP1,CABP1,DPYSL2,DLG1,DNM2,PPP1CA,CTTN,TLN2,PACSIN1,MYRIP,CPE,SNTB2,PRKAR2B,SLC17A5,ARF4,PIAS3,TRIM9,GRID2IP,DNM1L,MAP2,KCNK1,ITPKA,APBA2,NRGN,LZTS1,USH1C,SERPINE2,CALB2,STRN4,SLC1A3,APBA1,ITGA3,ZNRF2,RIMS3,FLRT3,CADPS2,NPTN,RIMS2,SHARPIN,SCRIB,CYFIP2,ILK,CDK5R1,RASGRP2,IL1R1,GABRD,HTT,ITGA7,ITPR1,NDE1,ARPC2,RUSC1,DRD1,NF2,SLC2A8,ERBB2,P2RX7,KCTD12,BCL2L1,PRKACA,PRR7,DACT1,DLG3,F2R,CLCN3,SEPT6,DMTN,CLSTN1,UTRN,PRKCQ,SYP,TANC1,DAG1,FYN,ATP1A1,SLC9A6,SIPA1L1,NRG1,PRIMA1,RGS14,PRKAR1A,FARP1,CPEB4,LRP4,EPS8,GABRG2,COL4A5,KCNC4,EFNB1,SRPX2,SNTA1,ANK1,ADD3,IGSF9,ADORA1,PTEN,CDK16,ANKS1B,MAGEE1,CPLX1,MAP3K7,CAMK2G,HCN3,DLGAP1,P2RX4,MOB4,SYPL1,CASK,RAB3B,RAPGEF2,GRIN1,VAMP3,SNTB1,MAPK8IP1,MAP1B,SYT7,FGFR2,ZMYND19,NETO2,ARRB1,GRIN2D,GPER1,L1CAM,CPEB2,SNPH |
| 4.614e-05 | -9.98 | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP | 182 | 47 | 17758 | 2588 |
CASP3,INPPL1,PINK1,GRHL2,DAP,ETV5,DNAJB11,GMCL1,BCL2L1,ART5,TTYH3,SLC9A3R2,TFAP4,IRF2BPL,FAM111A,TMEM87B,CST3,TFAP2A,VAT1,STEAP3,TECR,CTDSP2,SNX8,MLEC,TRIM8,HPS3,MFI2,PQLC3,OXR1,PLEKHO1,SHARPIN,CBX6,FURIN,KIF20B,MCFD2,BBS2,MAN2A2,NUDT16,DUOX1,TTC12,MMP17,PPM1H,MDH1,GLA,ALG2,LRRC57,SNX30 |
| 4.619e-05 | -9.98 | RHO GTPase Effectors | REACTOME pathways | R-HSA-195258 | 285 | 68 | 8202 | 1235 |
MYL9,SPC25,NF2,IQGAP1,KLC2,NDC80,RHPN2,NUF2,KIF2C,CENPN,KTN1,CALM2,CTNNB1,CDH1,KIF14,CDKN1B,TAX1BP3,CTTN,MYH14,DVL2,PLK1,CENPA,CDC20,AURKB,CDC25C,PPP2R5A,LIMK1,MYLK,PPP1CB,SGOL1,MYL12B,PPP2R5D,WASF3,PPP1R12A,CENPI,CIT,CDCA8,ERCC6L,CALM3,NCKAP1,SPDL1,PKN1,CKAP5,KIF5B,RAC2,NOXA1,PAK2,KLC3,PRC1,BUB1,KNTC1,IQGAP3,NUP85,NCOA2,RHOA,ZWINT,CENPC,B9D2,CALM1,DIAPH2,CYFIP2,SKA1,RHPN1,RHOB,CENPE,NDE1,ARPC2,NUP37 |
| 4.635e-05 | -9.98 | REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | REGULATION_OF_CATALYTIC_ACTIVITY | 271 | 64 | 17758 | 2588 |
CCNE2,SPRED1,RALBP1,TP53,ERBB2,CARD10,PICK1,CDKN2C,CCND1,RGS3,SERINC2,F2R,CDKN2D,CKS2,SOD1,CASP9,PKMYT1,PIF1,CDC25C,MAP3K6,VCP,EDNRA,RBL1,MADD,PPP2R4,STAT1,MAP3K11,KIAA1804,GLA,AIFM3,FGD1,TAOK2,CDKN1C,TRAF2,HERC5,TRIB2,PKN1,DIRAS3,RB1,CARD8,IRAK1,PTEN,PAK2,BAX,MAP3K9,CKS1B,MDFIC,HEXIM2,MAP3K7,PLCB2,CCDC88A,MDFI,STRADB,EGFR,CDK5R1,GNAS,CDK5RAP1,TSC1,ARAP1,FGD6,MAP3K5,CD81,HIPK3,IFI6 |
| 4.646e-05 | -9.98 | in utero embryonic development | biological process | GO:0001701 | 350 | 80 | 16441 | 2455 |
EMX1,ACVR1,GRHL2,ADD1,EPAS1,ST14,WDTC1,TP53,GATA3,PLAC1,BCL2L1,CCNB1,STIL,PDGFB,RCN1,CTNNB1,SMO,PLK4,TWIST1,ARNT2,ZBTB18,AKT1,TFAP2C,ICMT,ZFAND5,GINS4,EDNRA,SOCS3,HS6ST1,PLCG1,TANC2,APBA2,E2F8,GAB1,ARNT,MAFF,GRN,KLF2,CDKN1C,CCM2,TGFBR1,JAG2,NCKAP1,APBA1,ELF3,MECOM,CAPN2,BMP2,E2F7,CYR61,GATA2,MGAT1,OCRL,FUT8,MSH2,NEK2,ERCC2,WNT3A,TTPA,TMED2,MDFI,EPB41L5,HES1,SALL4,UBE2A,G2E3,EGFR,CNOT2,NCOA3,ACVRL1,FGFR2,SPINT2,PKD2,ZMIZ1,SOX8,FZD5,PLOD3,NCAPG2,CCNB2,EGLN1 |
| 4.658e-05 | -9.97 | immune response-activating signal transduction | biological process | GO:0002757 | 388 | 87 | 16441 | 2455 |
UNC93B1,TRIM5,INPP5D,RPS6KA1,PSME2,GATA3,CUL1,PSME1,ITPR2,PRKACA,CACNB4,CALM2,RPS6KA2,PSMD1,ELMO2,PSMC2,PLCG2,PIK3CA,PIK3CD,PDE4D,SCARA3,LGMN,NFKB2,RIPK2,TNIP1,ITCH,CR2,PRKCQ,DUSP4,ITPR3,PLCG1,FYN,PTPRJ,LIMK1,PSMD3,NOD2,IRF7,PPP2R5D,PSMC1,DDX58,HSP90B1,THEMIS2,TAB3,CTSB,PSMD7,PSMD10,BTN3A1,CALM3,PLD2,TEC,NCKAP1,VASP,IRAK1,PIK3AP1,PTEN,PAK2,BAX,MAPK11,MAP3K7,MAPK7,CNPY3,SYK,PSMA5,PSMB4,MAPKAPK3,MICB,CALM1,PIK3R1,YES1,CYFIP2,ELK1,FOS,BCAR1,PSMA4,BCL10,TXK,GPLD1,MAPKAPK2,CTSL,PELI2,ITPR1,NFKBIA,UBE2D2,NR4A3,ARPC2,IFIH1,RPS6KA3 |
| 4.658e-05 | -9.97 | negative regulation of molecular function | biological process | GO:0044092 | 1054 | 203 | 16441 | 2455 |
SIGIRR,CASP3,FAF2,PPP4R4,IBTK,DNAJC3,ARFGEF1,XIAP,F11R,PSME1,HDAC6,PDGFB,TP73,CALM2,CDKN2C,PSMD1,CABP1,SIVA1,RGS3,PSMC2,DUSP10,CRY2,CYP1B1,ZNF462,PLK1,ITCH,PRKAR2B,PIF1,AURKB,PPP1R14C,POR,NEIL1,CAMK2N2,LIMK1,PPP2R4,NOD2,CAB39,SERPINB6,SERPINI1,GLA,HSPB1,PSMC1,LMTK3,PPP1R2,CDKN1C,SERPINE2,PPP1R12A,UBASH3B,PSMD7,CALM3,DUSP5,SH3RF2,TFAP4,RB1,TIMP1,IGF1R,FBXO7,PAK2,NEK2,FNIP1,SORL1,PIM1,MAPK7,PSMA5,TMED2,MDFI,SOCS5,EPB41L5,CALM1,EPHA1,ILK,PSMA4,NFIB,PLIN5,FAS,PTPRF,PRKAG2,SEMA4D,HTT,NFKBIA,SH3BP4,PIAS2,NLRC5,AURKA,STK39,CABIN1,SERPINB1,IFI6,RPS6KA3,DRD1,EGLN1,SPRED1,NF2,NQO1,THRA,RPS6KA1,IQGAP1,PSME2,CAST,PTTG1,TP53,WDTC1,SYTL2,PER2,CD46,APLP2,SP100,RALB,PPME1,FICD,SMO,CDKN1B,DAB2IP,TWIST1,IFIT1,DLG3,CDKN2D,TMBIM1,CHP1,SIRT1,PPIF,CAMSAP3,TIMP2,BAG4,AKT1,CDC20,COX11,PKMYT1,ERBB2IP,DUSP4,SOCS3,IRS2,PTPRJ,PPP2R5A,STK38,WFS1,CORO1C,PSMD3,WWTR1,RGS14,PRKAR1A,ARFGEF3,ANXA3,FARP1,NKX3-1,SORT1,DAP,TRAF2,SERPINB9,HABP4,PSMD10,NES,AES,ANO9,PKN1,TRIB2,GSTP1,AIP,TIPRL,FZD6,SH2D4A,WWP2,CD109,CTNNBIP1,IRAK1,GNB5,PTEN,PPP1R10,BMP7,GPC3,CST3,BAX,ADAM15,H2AFY,TRIM21,TMBIM6,BUB1,HEXIM2,RAG1,GFI1,SPRY2,DUSP1,PSMB4,PLAUR,PPARA,FURIN,COL7A1,LEPR,MAPK8IP1,CDK5RAP1,TIMP3,SERPINA1,PRDX3,SPINT2,E2F1,SERPINB5,ARRB1,PKD2,NDFIP1,UBE2C,CPEB2,HIPK3,PKIA |
| 4.672e-05 | -9.97 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | 177 | 46 | 17758 | 2588 |
GRN,CD99,CASP3,TXN,HSP90B1,TMEM184B,ENO2,IBTK,LRRFIP2,DNAJC3,BIK,TAP1,NUCB2,CCNB1,NTAN1,PDIA4,CAPN2,CEP97,UBE2J1,RPN2,MANF,ETHE1,FAIM,PDIA6,FAM69A,NFE2L3,PCCB,SEC61B,AURKB,ATP1B1,RAD17,PLEKHB1,PRDX4,FAS,FUCA1,OSBPL2,ATP1A1,RCBTB2,CORO1C,STK38,CTSA,ATP1B3,SPCS3,ATP6V1C1,SLC27A3,DLAT |
| 4.672e-05 | -9.97 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN | 177 | 46 | 17758 | 2588 |
CASP3,GNPDA1,PARP14,FRMD6,TAP1,SELL,CD274,INTS8,SNX9,PGAP1,FANCI,SCML1,DTX3L,LMO4,SLC44A1,CDH3,ALPK1,LGMN,LRP11,MAST4,CRTAP,RNF169,LAMP3,PARP9,SUSD3,SIRT1,NFE2L3,TGIF1,RAPGEF2,CASP9,C3orf52,PTGER4,ATP1B1,DUSP4,PCTP,ADRBK2,STX3,CYB5A,PI4K2B,PELI2,STAT1,NETO2,PLEKHG1,IFIH1,TRPC3,MAFF |
| 4.712e-05 | -9.96 | nucleotide binding | molecular function | GO:0000166 | 2291 | 404 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ALDH1A3,ATP13A3,PIK3CA,AOX1,DNM2,TUBG1,CRY2,PIK3CD,ACOX2,TUBA4A,NEK4,NWD1,VPS11,SMARCA2,LOC81691,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,AURKB,TP53I3,POR,RAB2B,ARF4,ULK2,ENPP1,RBM47,DNM1L,PLK2,LIMK1,CELF5,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,AKAP17A,KIF23,MERTK,BMP2K,RAVER2,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,CNGA1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,PRODH,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,SRSF5,ATP8B3,PKM,ILK,GNA11,RHOB,PDE11A,STK17A,DHX32,DGKH,NT5C2,PRKAG2,CSNK1G1,DCK,AURKA,MDH1,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,TMEM173,XDH,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,AIFM2,PRKACA,FLT3,DDR1,MOCS1,RBM23,TRANK1,RALB,FICD,PDE4D,ACSL4,EPHB4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,AGPS,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,ACAD10,CDK19,STK26,AXL,KIAA1804,SLC27A1,RAB29,PDXK,MLKL,SLC27A3,MAPK12,PRKAR1A,GALK1,TNRC6C,TAOK2,HSP90B1,RBM24,ATP9A,ESRP1,ARL4C,PKN1,SPR,DNAH3,IFT27,RND1,DIRAS3,SLC27A6,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,RAPGEF2,UBE2A,AK4,PIM3,YES1,KIF11,TXK,ACADSB,FGFR2,ACVRL1,ABCB1,RYK,CSTF2,RABL6,CENPE,LRRK1,CMPK2,CPEB2,SRSF9,MELK,TNK1,NMRK1,ST13,CRYM,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PSMC2,PAPSS1,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,IDH1,CDK1,ADRBK2,STK17B,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,RBM43,PSMC1,RRAGD,PRKAA2,RUNX2,LMTK3,BVES,PEX6,ABCG2,TEC,RAB6A,DHRS3,MYO5C,DAZAP1,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,AHCY,PIM1,ACAD8,ABCC1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,CTBP1,UGP2,UPF3B,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,UPF3A,SEPHS1,MAP3K3,SIRT1,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,DUOX1,IDE,ATP1A1,STK38,PTK7,PTBP3,MAOA,XRCC3,RCAN2,AIFM3,ABCA1,PINK1,DYRK3,TOR4A,CPEB4,SHPRH,CIT,GNAL,GNE,ERCC6L,TGFBR1,TRIB2,TMEM63A,KIF5B,TOP2A,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,ATP2B1,MYO5A,RBMS2,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,HNRNPH2,RAP2C,UBE2D2,ACADM,GEM,UBE2C,HIPK3,ZBTB33,ABCG1 |
| 4.718e-05 | -9.96 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN | 172 | 45 | 17758 | 2588 |
DDX58,IL15RA,PARP14,ARHGEF11,SOD2,HERC5,SAMD9,HERC6,PGAP1,DUSP5,MXD1,TMCC3,OTUD1,TRANK1,CABP1,FJX1,IFIT1,OAS3,HCN3,LAMP3,AMOTL2,ARAP2,RIPK2,PLSCR1,SPATA18,PAPD7,ZSCAN12,IFIT3,FAS,NFIX,MDK,DHDH,GALNT3,PTGS2,HPSE,C19orf66,ZNF367,NLRC5,IRF7,HS3ST3B1,CMPK2,GLCCI1,IFI6,RARG,IRF1 |
| 4.747e-05 | -9.96 | CUI_TCF21_TARGETS_2_UP | MSigDB lists | CUI_TCF21_TARGETS_2_UP | 414 | 90 | 17758 | 2588 |
PAPSS2,TCTN2,EPHA4,HDAC11,PTTG1,NUF2,TAF6L,SLC7A2,MNS1,PDGFA,CCNA2,SRPX,UBE2T,CDKN1B,KIF22,CYP1B1,SOAT1,CAMSAP3,CENPA,COL6A2,CAPN6,SERTAD4,SYNE2,IGSF8,XRCC6BP1,LHFPL2,CLCN2,CDC25C,CDK1,EDNRA,NFIX,PRIM1,CXXC4,MDK,PLCH1,PAFAH1B3,NKD1,SIPA1L1,KIAA1804,MAOA,KLF5,EPB41L4A,CD99,CTHRC1,GALK1,FAM189A2,HJURP,ETV5,CDCA3,CDCA8,BEX2,PARM1,NRP2,HMGXB4,CKAP5,ADD3,PFKL,FRAS1,KCNK5,RANBP1,COL6A1,CKS1B,ZNF692,IGFBP2,CADPS2,MXD3,KNTC1,IQGAP3,NCAM1,TSPAN33,IGDCC4,HMMR,ADAMTS2,FBLN5,MAPKAPK3,ASPM,ANTXR1,RPL12,FAM64A,CDCA5,CDCA7L,MATN2,SLC4A3,OSCP1,ZMIZ1,ARSB,UBE2C,CCNB2,CBX5,ESPL1 |
| 4.765e-05 | -9.95 | ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | COSMIC cancer mutations | ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | 35 | 15 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR |
| 4.765e-05 | -9.95 | breast-hyperplasia-ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | COSMIC cancer mutations | breast-hyperplasia-ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | 35 | 15 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR |
| 4.768e-05 | -9.95 | AKT_UP.V1_UP | MSigDB lists | AKT_UP.V1_UP | 162 | 43 | 17758 | 2588 |
MAN2B2,TPRN,UGT8,CAMKK1,FBXO6,TMPRSS4,PARM1,SGPL1,TMCC3,CXCL16,KCNK5,DUSP10,VAT1,TNFRSF12A,TACSTD2,GOT1,IFIT1,LGMN,MYO5B,CD55,PLSCR1,GUSB,C3orf52,PYGL,AK4,NKAIN1,PDK3,FXR2,IFIT3,SEC14L2,MMP15,IL1R1,SLC6A6,PTPRJ,TJP3,GDE1,PLK2,SECTM1,CLMN,SH3BGRL2,MAL2,UNC5B,UBE2C |
| 4.793e-05 | -9.95 | EF-hand-dom_pair | interpro domains | IPR011992 | 260 | 62 | 18293 | 2672 |
MYL9,SLC25A24,REPS2,CAPN12,S100A11,SLC25A13,CALB2,RHBDL3,DGKA,CALM3,EFHD2,RASGRP3,NUCB2,S100A2,REPS1,HPCAL4,NCS1,PPP2R3A,SDF4,PLS3,CALM2,RCN1,CAPN2,NECAB3,CABP1,PLCB2,DGKG,S100A13,RASGRP1,S100A6,CHP1,GCA,KCNIP3,TBC1D8B,STAT4,S100A4,CALM1,UTRN,PLS1,CAPNS1,AIF1L,CBL,MCFD2,MYL12A,LCP1,NIN,RASGRP2,NUCB1,PLCG1,PLCH1,DUOX1,STAT6,CGREF1,NKD1,STAT1,S100A5,EFCAB14,PKD2,PPP2R3C,DRP2,CAPN1,EHD1 |
| 4.819e-05 | -9.94 | GTPASE_ACTIVATOR_ACTIVITY | MSigDB lists | GTPASE_ACTIVATOR_ACTIVITY | 59 | 21 | 17758 | 2588 |
DOCK4,ARAP3,RAPGEF2,RALBP1,RASA2,RGS20,ARFGEF1,RASGRP3,RACGAP1,RASA1,ABR,ARHGEF10L,RGS9,RGS12,RGS3,ARAP1,ARFGAP3,RGS5,ARHGAP4,RGS14,RAP1GAP |
| 4.819e-05 | -9.94 | HUPER_BREAST_BASAL_VS_LUMINAL_DN | MSigDB lists | HUPER_BREAST_BASAL_VS_LUMINAL_DN | 59 | 21 | 17758 | 2588 |
ENO2,HLA-F,BIK,VWA1,KLK6,PLA2G16,ALCAM,MYO5C,FUCA1,HLA-B,DDAH1,PROM1,MLPH,CYR61,CLDN4,HMGA1,HLA-C,LOXL1,GAD1,ANXA11,SEMA3B |
| 4.819e-05 | -9.94 | GNF2_RFC4 | MSigDB lists | GNF2_RFC4 | 59 | 21 | 17758 | 2588 |
ZWINT,FOXM1,ASPM,NDC80,KIF11,CDK1,FANCI,PRIM1,TOP2A,CCNA2,PCNA,RANBP1,PLK4,MSH2,CKS1B,KNTC1,UBE2C,CCNB2,MSH6,SMC4,CKS2 |
| 4.872e-05 | -9.93 | Effects of PIP2 hydrolysis | REACTOME pathways | R-HSA-114508 | 27 | 13 | 8202 | 1235 |
DGKH,ABHD12,DGKQ,ITPR1,DGKA,PRKCQ,ITPR2,ITPR3,DGKG,TRPC3,RASGRP1,DGKE,RASGRP2 |
| 4.905e-05 | -9.92 | nucleoside phosphate binding | molecular function | GO:1901265 | 2292 | 404 | 16491 | 2452 |
ACACB,ACVR1,AK7,ATP8A1,RET,TAP1,SMARCAL1,DHX8,CAMK1D,SEPT4,KIF26A,DAPK2,PAK6,WEE1,HELZ2,UBE2T,DNAH6,ALDH1A3,ATP13A3,PIK3CA,AOX1,DNM2,TUBG1,CRY2,PIK3CD,ACOX2,TUBA4A,NEK4,NWD1,VPS11,SMARCA2,LOC81691,KIFC2,ACVR1C,PBK,HSPA12A,PRKAR2B,KIF13A,PIF1,AURKB,TP53I3,POR,RAB2B,ARF4,ULK2,ENPP1,RBM47,DNM1L,PLK2,LIMK1,CELF5,ATP7B,MYLK,PPP2R4,NOD2,MAP3K11,MAPK13,RNASEL,ITPKA,ARF6,DDX58,RECQL,CDK17,NUAK1,DGKQ,PRKAA1,RAB23,AKAP17A,KIF23,MERTK,BMP2K,RAVER2,C9orf69,RAC2,CTPS1,NEK2,MSH2,DAPK1,ADCK2,MAP3K9,PRKG1,ALPK1,CNGA1,PIKFYVE,MAPK7,MAST4,DGKG,PHKG2,TTLL1,MCCC2,PRODH,KIF20A,ADCK3,MAPKAPK3,PIP4K2C,PYGL,KIF20B,EPHA1,SRSF5,ATP8B3,PKM,ILK,GNA11,RHOB,PDE11A,STK17A,DHX32,DGKH,NT5C2,PRKAG2,CSNK1G1,DCK,AURKA,MDH1,STK39,CDK18,MAP3K5,IFIH1,NRBP1,RPS6KA3,TMEM173,XDH,EHD1,DMPK,KIF3C,PAPSS2,NLRX1,TUBB4B,RPS6KA1,ACTR8,ATP2C2,ETNK1,TESK2,MAPK4,GRK6,AIFM2,PRKACA,FLT3,DDR1,MOCS1,RBM23,TRANK1,RALB,FICD,PDE4D,ACSL4,EPHB4,ARL4D,RAB27B,MYO5B,MX1,RIPK2,PFKFB2,AGPS,SEPT6,PANK1,VPS4B,TEP1,KIF1C,PRKCQ,ATP1B1,RAD17,PKMYT1,RAB38,ATP10D,NIN,EPHA10,FYN,JAK1,ACAD10,CDK19,STK26,AXL,KIAA1804,SLC27A1,RAB29,PDXK,MLKL,SLC27A3,MAPK12,PRKAR1A,GALK1,TNRC6C,TAOK2,HSP90B1,RBM24,ATP9A,ESRP1,ARL4C,PKN1,SPR,DNAH3,IFT27,RND1,DIRAS3,SLC27A6,IRAK1,FAM20B,SGK3,ATP8B1,MAPK11,ERCC2,AK3,ERBB3,MAP3K7,ITM2C,MSH6,SMC4,HCN3,OPLAH,PCCB,CASK,RAPGEF2,UBE2A,AK4,PIM3,YES1,KIF11,TXK,ACADSB,FGFR2,ACVRL1,ABCB1,RYK,CSTF2,RABL6,CENPE,LRRK1,CMPK2,CPEB2,SRSF9,MELK,TNK1,NMRK1,ST13,CRYM,CAMKK1,EPHA4,MCCC1,UBE2Q1,UBE2Z,VARS2,KIF2C,ABCD4,RAB15,RPS6KA2,CDKL5,ARL1,PAPSS1,PSMC2,PASK,ABCA2,KIF22,RAB20,RP2,MYH14,DDX59,STK35,PLK1,NLRP4,ATL1,MARK1,ARFRP1,ROR1,IDH1,CDK1,ADRBK2,STK17B,VCP,RHEB,PI4K2B,IARS2,PIK3C2B,RBM43,PSMC1,RRAGD,PRKAA2,RUNX2,LMTK3,BVES,PEX6,ABCG2,TEC,RAB6A,DHRS3,MYO5C,DAZAP1,UBE2Q2,IGF1R,PFKL,FAM20C,KIF13B,PAK2,PRKCI,SRP54,AHCY,PIM1,ACAD8,ABCC1,TESK1,STRADB,PDE5A,EIF2AK1,PDK3,PDIK1L,NUBP1,EGFR,GNAS,MAPKAPK2,NUDT16,INSR,PRPS2,RAB31,NLRC5,RHOBTB2,ALPK3,KIF12,JAK3,CTBP1,UGP2,UPF3B,ABCG4,TP53,DGKA,ERBB2,P2RX7,MRAS,CDK14,KIF14,SRR,PLK4,OAS3,SCYL3,HSPA2,UPF3A,SEPHS1,MAP3K3,SIRT1,CLCN3,AKT1,RFK,FIGNL1,MAP3K6,ARHGAP35,ATP13A2,DUOX1,IDE,ATP1A1,STK38,PTK7,PTBP3,MAOA,XRCC3,RCAN2,AIFM3,ABCA1,PINK1,DYRK3,TOR4A,CPEB4,SHPRH,CIT,GNAL,GNE,ERCC6L,TGFBR1,TRIB2,TMEM63A,KIF5B,TOP2A,ADRBK1,CDK16,GTF2F2,UBE2J1,ACTA2,SGK1,BUB1,ABCD1,HSPA13,SYK,CAMK2G,ATP2B1,MYO5A,RBMS2,P2RX4,RHOA,RAB3B,GCLC,NADK2,RUNX3,SPAG1,DGKE,DDX23,SWAP70,RND3,HNRNPH2,RAP2C,UBE2D2,ACADM,GEM,UBE2C,HIPK3,ZBTB33,ABCG1 |
| 4.911e-05 | -9.92 | gland development | biological process | GO:0048732 | 394 | 88 | 16441 | 2455 |
FOXM1,THRA,RPS6KA1,CAST,GATA3,ERBB2,PLXNA1,DDR1,CACNB4,CCND1,CYP1A1,TGFBR3,CTNNB1,CDH1,LMO4,ELF5,PIK3CA,SMO,ETV4,SOD1,AKT1,EZR,TFAP2C,ICMT,CLCN2,DAG1,IRS2,MDK,AREG,STAT6,ATP7B,TBX1,HOXA9,NRG1,PLXND1,ARF6,E2F8,COBL,CBX7,CAPN1,NKX3-1,CDKN1C,SERPINE2,SOX9,TGFBR1,ETS1,SIX4,ELF3,ZDHHC21,BMP2,E2F7,IGF1R,PTEN,GATA2,BMP7,CST3,HMGCL,CITED2,NTN1,RAG1,WNT3A,SLC12A2,IGSF3,HES1,AK4,SCRIB,NPHP3,NFIB,EGFR,PITX2,NCOA3,ONECUT1,INSR,FA2H,FGFR2,TWSG1,CSF1,SERPINB5,PKD2,HOXB13,USF2,CCNB2,SEMA3A,AHR,RARG,FOXA1,JARID2,XDH |
| 4.920e-05 | -9.92 | chr8p21 | MSigDB lists | chr8p21 | 72 | 24 | 17758 | 2588 |
NKX3-1,ZNF395,PBK,BNIP3L,ASAH1,TRIM35,LGI3,SORBS3,LOXL2,DOCK5,KCTD9,SH2D4A,EBF2,NPM2,PHYHIP,ANK1,ENTPD4,KIF13B,BMP1,RHOBTB2,NRG1,C8orf58,SCARA3,REEP4 |
| 4.920e-05 | -9.92 | KEGG_ADHERENS_JUNCTION | MSigDB lists | KEGG_ADHERENS_JUNCTION | 72 | 24 | 17758 | 2588 |
LMO7,PVRL4,WASF3,SORBS1,RHOA,IQGAP1,ERBB2,TCF7,TGFBR1,YES1,SSX2IP,EGFR,PTPRF,RAC2,FYN,PTPRJ,INSR,IGF1R,CDH1,CTNNB1,PVRL2,CTNND1,MAP3K7,FARP2 |
| 4.920e-05 | -9.92 | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | 72 | 24 | 17758 | 2588 |
ANXA3,LASP1,TM2D2,PRSS23,MORC4,LOXL2,PLA2G16,LGALS3BP,NRP2,LYSMD4,DPYSL3,PTPRF,GPRC5B,PLK2,CORO1C,CALD1,MATN2,FAM83D,AKR1B1,CD70,TRAM1,PTGES,DCBLD1,SULF2 |
| 4.925e-05 | -9.92 | Rac GTPase binding | molecular function | GO:0048365 | 42 | 17 | 16491 | 2452 |
DOCK4,SOD1,RALBP1,IQGAP1,EPS8,STRADB,NCKAP1,PKN1,PAK6,NOXA1,CDKL5,CORO1C,OCRL,PAK2,MAP3K11,ITPKA,ARHGAP4 |
| 5.064e-05 | -9.89 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | 81 | 26 | 17758 | 2588 |
PLA2G4A,SPRED1,MCTP1,CEP70,FRMD6,STAT4,SYBU,C5orf30,CALCRL,PBX3,IL18,FAM198B,HEATR5A,CA8,FLT3,ADRBK2,MECOM,SLC25A36,SCML1,ITGB8,HOXA9,INPP4B,KLF5,SERPINI1,LIMCH1,SCN2A |
| 5.073e-05 | -9.89 | WIERENGA_STAT5A_TARGETS_GROUP1 | MSigDB lists | WIERENGA_STAT5A_TARGETS_GROUP1 | 123 | 35 | 17758 | 2588 |
CDKN1C,FAM129B,CERCAM,NDRG1,CALB2,TGFBR1,CTSZ,FBXO6,DHRS3,PHLDA1,DUSP5,NCS1,SLC9A7,SNTA1,GATA2,A4GALT,VASN,DAPK1,PIM1,RASGEF1A,HSPA2,P2RX4,UBAC1,DPYSL4,TP53INP2,STK17B,MOSPD3,NAAA,SLC25A4,CTNS,P4HA2,SH3BP4,RAP1GAP,F2RL1,MIIP |
| 5.086e-05 | -9.89 | positive regulation of protein catabolic process | biological process | GO:0045732 | 250 | 61 | 16441 | 2455 |
DLGAP5,GGA1,SH3D19,DNAJB2,PSME2,CUL4B,SOX9,ASB9,PSMD7,CUL1,PSMD10,PSME1,TRIB2,CCNB1,SNX9,BARD1,APC2,BCAP31,PPP2R3A,IER3,RB1,PSMD1,RNF128,CTSC,PTEN,DACT1,GPC3,PSMC2,CDKN1B,SORL1,DAB2IP,OSBPL7,MYLIP,TIPARP,PSMA5,SOCS5,PLK1,VPS11,AKT1,PSMB4,ITCH,GCLC,NUB1,CDC20,FURIN,PRICKLE1,EZR,RNF19B,PSMA4,CDK1,VCP,GPLD1,PLK2,PSMD3,NKD1,AURKA,CD81,NDFIP1,UBE2C,ESPL1,PSMC1 |
| 5.156e-05 | -9.87 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN | 193 | 49 | 17758 | 2588 |
CCDC109B,TCF25,ATP8A1,DGKA,ITPR2,GPSM2,ETS1,CARD10,TMPRSS4,SH3KBP1,EPCAM,RALGPS2,CDH1,PHTF1,DAPK1,TPST1,KLC3,UBE2J1,DUSP10,RAG1,GFI1,ITM2C,MBP,RHOA,PQLC3,MPP1,MBNL3,SLC11A2,TNFAIP8L1,RAB3IP,ATP1B1,C3orf58,DGKE,CYB5A,SOCS3,LRRC42,PTPRF,TMEM50B,COQ10A,ETS2,AXL,SPINT2,NR4A3,AGFG2,EPB41L4A,PLIN3,GLCCI1,CBX4,TMEM131 |
| 5.156e-05 | -9.87 | GSE14308_TH1_VS_TH17_UP | MSigDB lists | GSE14308_TH1_VS_TH17_UP | 193 | 49 | 17758 | 2588 |
SLC35D2,IGFBP6,ST14,TMEM41B,KIF23,KCTD12,PSME1,KIF2C,CNTROB,MESDC2,CCDC92,CAPN2,FAM160A2,KCNN4,CENPJ,ZFP36,KIF14,TMEM51,SORL1,TRIM21,MXD3,TMEM37,IL10RB,SPRY2,NEB,DUSP1,NEK4,FADS2,ERMP1,GUSB,PAPD7,LGALS8,MRS2,XRCC6BP1,DGKH,NAAA,HPSE,RCBTB2,CSF1,STAT1,DGAT2,MLKL,ICOSLG,TTC39C,ZMIZ1,UBE2C,COBL,E2F8,NIPA1 |
| 5.156e-05 | -9.87 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP | 193 | 49 | 17758 | 2588 |
IL15,FAM129B,RASA2,IL18,CAMK1D,FAM91A1,NUCB2,FAM101B,FLT3,FAM46C,IL18R1,LTBP3,DNAJB9,SLC25A36,CCND1,SLC25A45,SESN3,CA2,DDHD2,TMEM51,BCL6,ECE1,C10orf54,PTPRE,TTPA,CASD1,MYLIP,IL10RB,ADAM17,TEF,S100A4,SPAG1,STX3,FRMD4B,IL1R1,GPRC5B,HOXA9,MYLK,PRDM5,APPL2,RAB31,PKD2,LRRK1,GEM,CD81,ABCA1,JARID2,FAM134B,CD33 |
| 5.156e-05 | -9.87 | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN | 193 | 49 | 17758 | 2588 |
EPAS1,PDCL,KIF2C,MGST2,ITPR2,PLA2G16,RAC2,PPP4R1,FUT8,CAPG,PRC1,CKS1B,BUB1,HMGCL,KNTC1,PDIA6,GFI1,PSMA5,MYO5A,SMC4,IGSF3,FAH,TDP1,DDB2,MLEC,KIF20A,LAP3,ITCH,CASP9,CDC20,FHL2,NUSAP1,BLVRA,POLD3,SLC25A5,VCP,FECH,DNM1L,NEIL3,DHTKD1,AURKA,GLA,CENPE,CBX5,CCNB2,SERPINB1,ESPL1,MELK,GOLGB1 |
| 5.161e-05 | -9.87 | regulation of dephosphorylation | biological process | GO:0035303 | 154 | 42 | 16441 | 2455 |
SPRED1,PINK1,FARP1,LMTK3,PPP4R4,HSP90B1,PPP1R2,PPP1R12A,NUAK1,IQGAP1,CALM3,TIPRL,SH2D4A,PPP2R3A,SYTL2,SH3RF2,CALM2,BMP2,ADORA1,NPNT,PPME1,CRY2,DLG3,SLC39A10,PPP6R1,CHP1,CAMSAP3,BAG4,CALM1,CDCA2,PKMYT1,GPLD1,TSC1,SWAP70,PPP2R5A,SEMA4D,HTT,PPP2R4,CNEP1R1,PPP2R2D,PPP2R5D,ARFGEF3 |
| 5.164e-05 | -9.87 | signet_ring_adenocarcinoma | COSMIC cancer mutations | signet_ring_adenocarcinoma | 21 | 11 | 17775 | 2585 |
CTNNB1,CDH1,AKT1,PTEN,SDC4,MSH2,PIK3CA,TP53,EZR,ERBB2,MSH6 |
| 5.164e-05 | -9.87 | stomach-carcinoma-signet_ring_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-signet_ring_adenocarcinoma | 21 | 11 | 17775 | 2585 |
CTNNB1,CDH1,AKT1,PTEN,SDC4,MSH2,PIK3CA,TP53,EZR,ERBB2,MSH6 |
| 5.189e-05 | -9.87 | V$IRF7_01 | MSigDB lists | V$IRF7_01 | 240 | 58 | 17758 | 2588 |
DDX58,ELK4,PARP12,TAP1,ERBB2,PSME1,PHLPP1,PCBP1,SRPX2,LGALS3BP,IL22RA1,DTX3L,FOXP2,CXCL16,ARTN,PPP1R10,CALD1,LYPD6,LHX6,POLL,BCL6,TRIM21,IRF2,MXD3,RFX5,PIK3CD,PDE4D,ARMCX6,RASGEF1A,DLX4,PDGFC,PCGF5,TAF5,USP18,CDYL,SAT1,KIF13A,LDB2,FOS,PNKD,KDM3A,COL12A1,OPTN,NFIX,PITX2,TSC1,TAPBP,CASP7,C19orf66,RBL1,CCDC6,PAPD5,SIPA1L1,FIBCD1,NR4A3,NR4A2,ARF6,CBX4 |
| 5.255e-05 | -9.85 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | 188 | 48 | 17758 | 2588 |
DDX58,ALDH6A1,ZNF395,FAM102B,PBX3,FBXO6,CAMK1D,MGST2,SEPT4,HLA-A,CD46,FAM111A,SLC25A45,DNPEP,RALB,CYP2S1,FDXR,DUSP10,TRIM21,IL17RA,IRF2,CNPY3,TRAM1,FLOT2,PARP9,SMARCA2,ING1,HPS3,ERMP1,CLSTN1,EIF2AK1,DOCK5,MFSD7,TCN2,PRIM1,FECH,HLA-B,STX10,RCBTB2,PRCP,CORO1C,PGRMC1,NOD2,OSCP1,STARD13,CPPED1,DLAT,CTDSP1 |
| 5.255e-05 | -9.85 | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | 188 | 48 | 17758 | 2588 |
LGALS3,CD63,CD82,IQGAP1,CAST,PTTG1,EPHA4,NDC80,CBLL1,EFHD2,SPSB1,TSPAN17,DUSP5,WEE1,TGFBR3,CTSC,RGS3,OSBPL3,PAPSS1,DUSP10,TAGLN2,FAR2,MYBL1,MYO5A,ABCC1,CASK,RAPGEF2,S100A4,DENND1B,PARP4,EZR,CAPNS1,EIF2AK1,RNF19B,ZDHHC3,SPAG1,ARHGAP35,FAS,SLC6A6,MPRIP,RAB11FIP1,NOD2,AGFG2,CTSA,EIF4EBP2,PIEZO1,MAP3K5,AHR |
| 5.258e-05 | -9.85 | chrxq24 | MSigDB lists | chrxq24 | 39 | 16 | 17758 | 2588 |
LAMP2,LONRF3,SEPT6,CUL4B,UBE2A,C1GALT1C1,NKRF,IL13RA1,DOCK11,SLC25A5,SLC25A43,PLS3,WDR44,ZCCHC12,RPL39,SLC9A6 |
| 5.269e-05 | -9.85 | MODULE_253 | MSigDB lists | MODULE_253 | 21 | 11 | 17758 | 2588 |
MAP2,TUBB4B,SNTB2,KIF14,KIF23,KIF2C,CENPE,ARSB,KIF11,MAP1B,TUBA4A |
| 5.308e-05 | -9.84 | Golgi subcompartment | cellular component | GO:0098791 | 281 | 66 | 17570 | 2579 |
ARFGEF1,RGS20,TGOLN2,SNX9,BCAP31,CHST2,SLC9A7,NCS1,CHPF,INPP5E,AP1M2,CDH1,ARL1,FUT1,DNM2,RAB27B,SULF2,CPD,ATL1,COG2,LAP3,KIF13A,SLC11A2,ARFRP1,RAB38,OPTN,STX10,WIPI1,ATP7B,CANT1,RAB29,B4GALT3,ST3GAL1,ARFGEF3,PIFO,GOLIM4,SORT1,SCOC,ATP9A,BACE1,RAB6A,B4GALT4,HLA-A,FUT2,NECAB3,OCRL,FUT8,SORL1,TMED2,GCNT1,NAGPA,B3GALT6,MOB4,CHSY3,GCC2,FURIN,FBXO8,FAM109A,GALNT3,GNAS,NUCB1,ARAP1,CSGALNACT1,RAB31,GPER1,GOLGB1 |
| 5.345e-05 | -9.84 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP | 183 | 47 | 17758 | 2588 |
LZTFL1,LGALS3,EPAS1,CAST,EFHD2,CYB561,FAM198B,DSE,S100A2,SLC20A1,PHLDA1,LMNA,XPR1,TIMP1,CTSC,ENPP5,FAM84B,RASGEF1A,FAR2,MAPK7,GFI1,MYBL1,APOBEC3G,MMD,WNT10B,S100A4,MPP1,ATP1B1,B3GALNT2,C3orf33,STX3,SLC44A3,ONECUT1,HLF,WIPI1,PRCP,WWTR1,FAM110C,PLEKHG1,ABCB1,PLOD3,AHR,RARG,TMEM173,FBXW5,RGMA,CTDSP1 |
| 5.345e-05 | -9.84 | HLA-A (major histocompatibility complex, class I, A) | protein interactions | 3105 | 67 | 24 | 16036 | 2547 |
HLA-E,TAP1,PDIA3,ERBB2,ILK,BCAP31,HLA-A,EGFR,VCP,GNAS,CALR,HLA-B,CD8A,APLP2,TAPBP,IRAK1,UBE2J1,HLA-C,ERBB3,SCARA3,LMAN1,TRAM1,COPG1,PRKAR1A |
| 5.399e-05 | -9.83 | ATAAGCT,MIR-21 | MSigDB lists | ATAAGCT,MIR-21 | 109 | 32 | 17758 | 2588 |
RMND5A,NF2,EPHA4,TRAPPC8,BAHD1,PCBP1,PER2,WWP1,BTBD3,SPRY2,RASGRP1,ACBD5,THRB,PSRC1,PIK3R1,PPARA,NFIB,RHOB,ARHGAP24,PITX2,AP1AR,TIMP3,MPRIP,ZNF367,MATN2,ZNF704,YOD1,OSR1,GLCCI1,RPS6KA3,CBX4,EHD1 |
| 5.431e-05 | -9.82 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | 43 | 17 | 17758 | 2588 |
ELK3,RUNX2,EGR3,DUSP4,GOLT1A,PHLDA1,DUSP5,MXD1,MAP1B,CTGF,AREG,REEP1,SPRY4,GEM,RASGEF1A,MAP3K5,MAFF |
| 5.431e-05 | -9.82 | ZHAN_MULTIPLE_MYELOMA_HP_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_HP_DN | 43 | 17 | 17758 | 2588 |
S100A4,TCFL5,NES,IL27RA,DOCK11,NTAN1,SGPL1,TIMP1,CST3,OPN3,CKS1B,TMBIM6,EIF4EBP2,TAGLN2,ST3GAL1,PDIA6,PKIA |
| 5.439e-05 | -9.82 | KOHOUTEK_CCNT1_TARGETS | MSigDB lists | KOHOUTEK_CCNT1_TARGETS | 47 | 18 | 17758 | 2588 |
ARL4C,FHL2,STMN3,CAPNS1,COL7A1,GALM,PATL2,DNER,BBS2,CXCL16,PTER,ENPP5,BMP1,FAM102A,CLDN4,TACSTD2,TINAGL1,S100A13 |
| 5.439e-05 | -9.82 | PID_IL6_7_PATHWAY | MSigDB lists | PID_IL6_7_PATHWAY | 47 | 18 | 17758 | 2588 |
HSP90B1,AKT1,PIK3R1,BCL2L1,FOS,SOCS3,PIAS3,TIMP1,JAK1,IL6ST,LMO4,MITF,STAT1,PIK3CA,MAPK11,PTPRE,GAB1,IRF1 |
| 5.442e-05 | -9.82 | Oocyte meiosis | KEGG pathways | ko04114 | 112 | 34 | 6908 | 1076 |
CCNE2,CPEB4,RPS6KA1,PTTG1,CALM3,CUL1,ITPR2,CCNB1,PRKACA,CALM2,RPS6KA2,IGF1R,BUB1,PPP1CA,CAMK2G,REC8,PLK1,CALM1,CDC20,PKMYT1,ITPR3,CDC25C,CDK1,PPP2R5A,ITPR1,PPP1CB,AURKA,CCNB2,SGOL1,CPEB2,ESPL1,PPP2R5D,RPS6KA3,MAPK12 |
| 5.442e-05 | -9.82 | Oocyte meiosis | KEGG pathways | hsa04114 | 112 | 34 | 6908 | 1076 |
CCNE2,CPEB4,RPS6KA1,PTTG1,CALM3,CUL1,ITPR2,CCNB1,PRKACA,CALM2,RPS6KA2,IGF1R,BUB1,PPP1CA,CAMK2G,REC8,PLK1,CALM1,CDC20,PKMYT1,ITPR3,CDC25C,CDK1,PPP2R5A,ITPR1,PPP1CB,AURKA,CCNB2,SGOL1,CPEB2,ESPL1,PPP2R5D,RPS6KA3,MAPK12 |
| 5.453e-05 | -9.82 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | 138 | 38 | 17758 | 2588 |
ENO2,FRMD6,RUSC2,NDRG1,SDC4,GATA3,IL13RA1,ETS1,MERTK,PHLDA1,MXD1,RND1,ACAP2,CTGF,CYR61,ZFP36,SGK1,SPRY2,SOAT1,NAGPA,TGIF1,SAT1,PTGER4,VWA1,PIM3,DUSP4,FOS,BCL10,PGF,SERTAD2,PLK2,NFKBIA,MPP2,APPL2,PRKCDBP,NFKBIZ,SPRY4,PDPR |
| 5.541e-05 | -9.80 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN | 168 | 44 | 17758 | 2588 |
DDX58,IL15RA,IL15,PARP14,TRIM5,HAPLN3,TRAF2,ELOVL7,TAP1,UBE2Z,BTN3A1,SAMD9,PATL2,HERC6,PGAP1,MXD1,TMCC3,PLS3,DTX3L,FAM111A,KCNK5,PLEKHF1,APOBEC3G,MX1,TGIF1,LOC81691,ARAP2,ZSCAN12,AURKB,FAS,DGKH,PTGS2,PI4K2B,HPSE,FGFR2,TRIM69,C19orf66,SECTM1,IRF7,HS3ST3B1,IFIH1,GLCCI1,CSRP2,IRF1 |
| 5.666e-05 | -9.78 | GCACCTT,MIR-18A,MIR-18B | MSigDB lists | GCACCTT,MIR-18A,MIR-18B | 114 | 33 | 17758 | 2588 |
TRIM2,FRMD4A,GRHL2,MAN1A2,CTDSPL,C5orf30,UBE2Z,TEX2,TRIB2,NFAT5,BTG3,HSF2,ADD3,CTGF,XYLT2,IRF2,PACSIN1,CCDC88A,SOCS5,PHF20L1,NR3C1,GCLC,ALCAM,PTGFRN,GIGYF1,PIAS3,RAB11FIP2,CDK19,ZNF367,TRIOBP,ZNF704,SH3BP4,GAB1 |
| 5.674e-05 | -9.78 | FRIDMAN_SENESCENCE_UP | MSigDB lists | FRIDMAN_SENESCENCE_UP | 77 | 25 | 17758 | 2588 |
SOD1,ING1,IGFBP6,CDKN1C,S100A11,TP53,HTATIP2,MAP1LC3B,RHOB,OPTN,RABGGTA,CCND1,CTGF,ALDH1A3,STAT1,RAB31,TFAP2A,IRF7,IGFBP2,NRG1,CITED2,CDKN2D,HSPA2,IGSF3,CYP1B1 |
| 5.699e-05 | -9.77 | regulation of immune system process | biological process | GO:0002682 | 1509 | 278 | 16441 | 2455 |
LAMP1,LGR4,TRIM5,TSC22D3,XIAP,TAP1,CUL1,NRG2,GATA3,PSME1,IL18,CAMK1D,ELMOD2,CALM2,DAPK2,PHYHIP,PSMD1,AP1M2,ELMO2,IL31RA,PIK3CA,PIK3CD,APOBEC3G,TNIP1,CASP9,SLC35C1,AGO4,MYOM1,ABR,PLCG1,LIMK1,TRAF3IP1,MYLK,NOD2,F2RL1,GAB1,DDX58,DHPS,THEMIS2,HLA-E,SOX9,SLC1A3,MERTK,CALR,RAC2,ZCCHC17,WDFY1,PIK3AP1,FBXO7,FAM13B,ALPK1,NCAM1,MAPK7,SOCS5,KLK5,MAPKAPK3,MICB,CALM1,ANO6,WHSC1,ELK1,CYFIP2,PSMA4,RASA1,FAS,PELI2,ITPR1,MDH1,KLK7,ARPC2,IFIH1,RPS6KA3,TMEM173,IRF1,SPRED1,NLRX1,INPP5D,RPS6KA1,CD274,EGR3,PRKACA,FLT3,TNFSF9,CD46,NOV,CDH1,CDKN1B,DAB2IP,PDE4D,IFIT1,RASGEF1A,LGMN,FLOT2,RIPK2,LGALS8,PRKCQ,ATP1B1,ITPR3,IRS2,FYN,JAK1,AXL,INPP4B,STAT1,NRG1,ARNT,PRKAR1A,HSP90B1,TNRC6C,TRAF2,FLOT1,BTN3A1,HERC5,PLD2,PKN1,ETS1,FGF19,EFNB1,ICAM1,HLA-A,CTNNBIP1,IRAK1,PTEN,BAX,TMBIM6,IGFBP2,MAPK11,ERBB3,MAP3K7,RAG1,GFI1,CNPY3,MSH6,PARP9,RASGRF1,PLSCR1,MPP1,RAPGEF2,PIK3R1,GRIN1,VAMP3,YES1,FOS,TXK,GPLD1,FGFR2,SLC35B3,NR4A3,ERAP1,GRIN2D,GPER1,FZD5,CD81,TMEM131,CASP3,UNC93B1,LMCD1,ITPR2,PDGFB,CACNB4,SPTB,RPS6KA2,CTNNB1,SHC3,TSPAN6,IL6ST,MITF,PSMC2,DLG1,DUSP10,TNFRSF18,SLC39A10,SCARA3,PTPRE,RASGRP1,SMAGP,SOD1,CD55,USP18,ITCH,EZR,CR2,GPRC5B,HOXA9,PPP2R5D,PSMC1,LGALS3,HLA-F,RASA2,UBASH3B,PSMD7,CALM3,NCKAP1,TEC,PHLPP1,DUSP5,RB1,VASP,CA2,GATA2,KCNN4,PAK2,FNIP1,C10orf54,HLA-C,WNT3A,PSMA5,PDE5A,EGFR,SOX13,MAPKAPK2,GNAS,PVRL2,CSF1,PHLPP2,NFKBIA,NLRC5,FAM213A,JAK3,RARG,GAS2L1,IL15,PSME2,P2RX7,ERBB2,RASGRP3,IL27RA,SLC7A2,PDGFA,PLCG2,BCL6,TMEM64,NFKB2,FRS3,SIRT1,AKT1,PTGER4,ERBB2IP,CD40,DUSP4,SOCS3,PTPRJ,STAT6,PSMD3,IRF7,SPTBN5,TAB3,CTSB,SERPINB9,PSMD10,SELL,ITGA2B,ADORA1,SYK,CAMK2G,HES1,RHOA,ADAM17,PSMB4,NR4A1,RGCC,FXR2,BCAR1,CD83,BCL10,CTSL,HLA-B,CD8A,SWAP70,BANK1,FGF18,NMI,UBE2D2,PPP2R3C,ICOSLG,NDFIP1,AHR,CD33 |
| 5.710e-05 | -9.77 | TyrKc | smart domains | SM00219 | 88 | 29 | 9131 | 1455 |
TNK1,EPHA4,RET,ERBB2,TEC,ROR1,YES1,EPHA1,FLT3,DDR1,MERTK,EGFR,TXK,EPHA10,INSR,FYN,JAK1,IGF1R,FGFR2,AXL,PTK7,RYK,KIAA1804,MAP3K11,MAP3K9,ERBB3,EPHB4,JAK3,SYK |
| 5.727e-05 | -9.77 | adenoma-nodule-goitre | COSMIC cancer mutations | adenoma-nodule-goitre | 64 | 22 | 17775 | 2585 |
TRIM24,AKT1,RET,TP53,ERBB2,IDH1,FLT3,KTN1,GNA11,EGFR,GNAS,RB1,CTNNB1,CDH1,PTEN,FGFR2,CCDC6,PIK3CA,SMO,TFG,JAK3,PRKAR1A |
| 5.748e-05 | -9.76 | ACTIN_FILAMENT_BUNDLE_FORMATION | MSigDB lists | ACTIN_FILAMENT_BUNDLE_FORMATION | 12 | 8 | 17758 | 2588 |
ARHGEF10L,TSC1,SORBS1,NF2,ARAP1,EZR,SORBS3,SHROOM2 |
| 5.822e-05 | -9.75 | PROTEIN_METABOLIC_PROCESS | MSigDB lists | PROTEIN_METABOLIC_PROCESS | 1211 | 224 | 17758 | 2588 |
CASP3,SIGIRR,TNK1,ACVR1,ST13,AGRN,SSH1,AASS,RET,FBXO2,IL18,ISOC2,HDAC6,ERP29,SLC9A3R2,PICK1,DAPK2,CDKL5,P4HB,IL31RA,CAPG,FUT1,DUSP10,RP2,PPP1CA,TLN2,PTPRE,IL1RAP,METAP2,NEK4,PTPN18,MARK1,TNIP1,RNF11,CDA,ERP44,LOXL2,GALNT7,ICMT,ANLN,STK17B,VCP,HS6ST1,MID1IP1,HPSE,DOLPP1,LIMK1,PPP2R4,MYLK,MAP3K11,NOD2,BMP1,POMT1,ARF6,HSPB1,PCSK5,PRKAA2,CDK17,DHPS,PEX6,DNAJB2,PRKAA1,APBA1,MERTK,TSPAN7,DUSP5,RABGGTA,ATG4A,B3GALNT1,IGF1R,TIMP1,PAIP2B,RPL39,NECAB3,PAK2,FBXO7,TBCD,TPST1,DAPK1,MAP3K9,PRKG1,PRKCI,PIM1,STT3B,MYLIP,GAD1,CCDC88A,NAGPA,PIGC,QSOX1,UFD1L,DDB2,PTPRH,MGAT4B,STRADB,EIF2AK1,ILK,NUBP1,RANBP9,NMT2,EGFR,RASA1,GLCE,FAS,STK17A,MAPKAPK2,MMP15,TSC1,INSR,FNTA,AURKA,ALG2,JAK3,CTBP1,DMPK,REPS2,NF2,ST14,HDAC11,TP53,PDIA5,TESK2,ERBB2,MAPK4,APC2,ZFYVE9,EPM2A,CCND1,PPME1,PLK4,RPN2,LMAN1,PHKA2,PDIA6,F2R,LOXL1,SEPHS1,ATG4D,SIRT1,MAP3K3,CDKN2AIP,BAG4,AKT1,TCEB2,PTPRU,COG2,PTPN9,CDC20,COX11,DUSP4,CD40,CBL,MAP3K6,DAG1,CASP4,ZMPSTE24,TAPBP,ALDH5A1,IDE,PTPRJ,STK38,STAT1,KIAA1804,NRG1,HS3ST3B1,RPL22,MAPK12,WASF3,DYRK3,PINK1,CTSB,BACE1,MAN1A2,TRAF2,TGFBR1,CTSZ,FBXO6,POMGNT1,PKN1,TRIB2,SBF1,AIP,PPP2R3A,WWP2,IRAK1,FUT2,PTEN,CDK16,CENPJ,MGAT4A,FUT8,RRBP1,CD9,BAX,SGK3,SGK1,WWP1,ERBB3,SLC35A1,SYK,GCNT1,AMFR,PARP4,FURIN,VAMP3,UBE2A,YES1,PRDX4,BCL10,TXK,CASP7,ACVRL1,PLOD2,UBE2D2,CSGALNACT1,NR4A3,ERAP1,HMGA1,PLOD3,CD81,UBE2C,HIPK3,OCLN,ABCG1 |
| 5.889e-05 | -9.74 | EF_HAND_1 | prosite domains | PS00018 | 177 | 47 | 11866 | 1802 |
MYL9,SLC25A24,REPS2,CAPN12,S100A11,CALB2,DGKA,CALM3,RASGRP3,NUCB2,S100A2,REPS1,HPCAL4,PPP2R3A,SDF4,NCS1,PLS3,CAPN2,RCN1,CALM2,NECAB3,CABP1,DGKG,S100A6,RASGRP1,GCA,KCNIP3,TBC1D8B,S100A4,CALM1,CAPNS1,PLS1,MCFD2,MYL12A,LCP1,RASGRP2,NUCB1,DUOX1,PLCH1,PLCG1,GNPTAB,NKD1,CGREF1,S100A5,PPP2R3C,CAPN1,EHD1 |
| 5.900e-05 | -9.74 | EF_HAND_2 | prosite domains | PS50222 | 217 | 55 | 11866 | 1802 |
MYL9,SLC25A24,REPS2,CAPN12,S100A11,SLC25A13,CALB2,RHBDL3,DGKA,CALM3,EFHD2,RASGRP3,NUCB2,S100A2,REPS1,HPCAL4,NCS1,PPP2R3A,SDF4,PLS3,CALM2,RCN1,CAPN2,NECAB3,CABP1,DGKG,RASGRP1,S100A6,CHP1,GCA,KCNIP3,TBC1D8B,S100A4,CALM1,PLS1,CAPNS1,AIF1L,MCFD2,MYL12A,LCP1,NIN,RASGRP2,NUCB1,PLCG1,PLCH1,DUOX1,SWAP70,GNPTAB,CGREF1,NKD1,S100A5,EFCAB14,PKD2,CAPN1,EHD1 |
| 5.916e-05 | -9.74 | cervix-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-squamous_cell_carcinoma | 12377 | 1883 | 17775 | 2585 |
HECA,FAM160B1,IBTK,AK7,SLC25A13,HEXB,RET,MCOLN3,CCNO,TRAPPC8,TGOLN2,BAIAP3,DPP8,SNX9,SPSB1,CARD10,LTBP3,ZNF275,GRM5,LYPD5,NPM2,PHYHIP,MUC4,UBE2T,DNM2,CRY2,PPP1CA,TMEM37,RNF26,WBP4,TIAM1,CPE,TIPARP,MGAT5,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,DSTN,TMEM98,KDELR3,TMEM151A,TFAP2C,RNF19B,PNKD,ABR,ARF4,PIAS3,ENPP1,PLCG1,ATP7B,CELF5,FAM114A1,TRAF3IP1,NOD2,TMOD2,RNASEL,ITPKA,STARD13,HSPB1,ANXA11,ZNF720,NXT2,SCN5A,GGA1,MTL5,RAB23,GPSM2,CCDC64B,FAM21C,HPCAL4,RABGGTA,FLII,SH3D21,RAC2,ZCCHC17,FRY,PAIP2B,ATP5H,MEGF8,FBXL14,PCYOX1,MAP3K9,CADPS2,USP1,USP38,FAM84B,ALPK1,PANX2,CNGA1,MAPK7,ZMYM1,DGKG,ULBP2,KANK3,NUP85,PPP6R1,TTLL1,HPS3,PQLC3,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,SFXN5,GNA11,PLIN5,MAGED2,IL1R1,CACHD1,FNTA,SLC4A4,ETS2,RAET1L,DGAT2,CLMN,GDF11,RUSC1,ADAMTS16,DMPK,DOCK9,WDR63,TPRN,NQO1,LFNG,RHBDL3,FAM91A1,MOCS1,REPS1,APPBP2,RBM23,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,SNX10,SZRD1,TMCC2,MX1,SNX8,SEC61B,COL6A2,ERMP1,C6orf1,RIPK2,APOBEC3D,PFKFB2,AGPS,SEPT6,VPS4B,SYP,DNAJB14,TANC1,GTF2A2,ZNF618,TRIM7,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,SHROOM3,CORO1C,WFS1,AXL,PNPLA6,FAM149A,DMWD,PRIMA1,SLC25A30,HSP90B1,MPZL1,FAM189A2,CKAP2,GCAT,ESRP1,BACE1,TRAF2,BIK,HABP4,CCM2,SDC4,OSGIN2,BTN3A1,CTSZ,ZNF219,PLPPR4,NFAT5,CTNNBIP1,DIRAS3,ZFX,FUT2,ITGB8,IGSF9,KNDC1,GPC3,MGAT4A,TMEM62,CST3,TUBGCP6,FAM20B,KLC3,ZFAND4,FAM102A,RAG1,CASD1,MED22,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,CXorf57,PGBD1,RAB3IP,CNTNAP1,PROM1,RPL12,RAB11FIP2,SYT7,SLC35B3,SSNA1,ITGAV,OSR1,CMPK2,ACOT7,SRSF9,PHC1,TLL2,TMEM131,ILDR1,TNK1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,PHOSPHO1,DNAJB11,TEX2,F11R,NENF,GALM,MGAT5B,ITPR2,SPTB,FANCI,TFAP2E,PLS3,SUSD2,INPP5E,ENTPD4,RPS6KA2,NUP210,CTNNB1,RABEP2,P4HB,IL6ST,PSMC2,PAPSS1,SLC44A1,TMEM143,ABCA2,NTN4,SMAGP,PLK1,MARK1,KCNIP3,CELSR2,STAU2,CBX6,NFE2L1,CR2,CCBL2,CKAP2L,NKAIN1,TRUB1,DZIP1L,KDM4D,TRIM9,TNS4,PLEKHG6,TMEM164,KCNMB4,AGPAT2,ARRDC1,KPNA2,TTC39C,TC2N,PARP12,RUNX2,USH1C,HJURP,LGALS3,DNAJB2,RASA2,SORBS3,ADCK5,RAB6A,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,NTN1,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,RGMB,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,CDK5R1,PRX,NMT2,C18orf8,RASGRP2,FOXD2,FA2H,COL13A1,KBTBD2,PHLPP2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,AKIP1,SEMA3A,CDAN1,USP43,RAD21,HOXB7,TMX4,TP53,RHPN2,P2RX7,BAHD1,PCBP1,PRR7,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,TACC2,PPME1,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,ERLEC1,AKT1,KIAA0040,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,ZNF628,TAPBP,IDE,PTPRJ,RBL1,STK38,MAOA,XRCC3,EFNA5,IRF7,SYT13,ARHGAP4,ST3GAL1,BIN1,ZMAT1,PINK1,CDH22,CPEB4,KLHL13,TAB3,CTSB,SCD5,GNAL,MCTP2,HAL,ERCC6L,ERI2,GTF3A,AIP,LBR,PARM1,IL22RA1,H1FX,NRP2,FZD6,M6PR,ZDHHC21,CD109,C16orf74,FOXP2,ALPP,LYPD6,TFAP2A,GTF2F2,TRIM21,TSPAN13,CPLX1,HMGCL,SYK,ATP2B1,LRRC24,DUSP1,NFE2L3,P2RX4,HES1,FBLN5,RHOA,MOSPD2,HMGN5,GUSB,STMN3,PRICKLE1,DPP9,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,USP6,DDX23,CNOT2,SCG2,NEIL3,FGF18,E2F1,ICOSLG,PTGES,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,LAMP1,PNISR,LGR4,SSH1,HSPG2,TSC22D3,CUL1,PDGFRL,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,CYP1A1,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,TACSTD2,ARMCX6,ACVR1C,CDYL,SLC35C1,KIF13A,LDB2,RAB2B,PRIM1,ANKRD10,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,SERPINI1,SPRY4,CCDC97,FGD1,SEMA6B,RECQL,MRC2,SCOC,DHPS,TBC1D1,TMEM55B,AKAP17A,APBA1,PDXDC1,TSPAN7,PSIP1,SH3RF2,MESDC2,C9orf69,CALR,DOPEY2,RALGPS2,LYPD3,ZNRF2,VASN,RPL39,AIM1,MSH2,DAPK1,PRKG1,TMEM51,TPST1,ADCK2,C8orf58,CACNA1D,DLX4,KCTD3,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,SPATA20,GCC2,PRODH,KCNJ12,KLK5,PRSS23,CEP89,ADCK3,LPGAT1,CALM1,DCHS1,PYGL,WHSC1,ATP8B3,ANTXR1,PDE11A,MMP15,NT5C2,AP1AR,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,PIAS2,FAM83D,MPP2,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,SAMD8,ZBTB34,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,GPR107,CAPN12,REPS2,ST14,CCDC110,THRA,DDIT4L,NDRG1,CERCAM,RALBP1,ATP2C2,BCL2L1,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPS8L2,C11orf84,CD46,APOBEC3B,CCNA2,ACAP2,TRANK1,EPHB4,OSBPL7,SULT2B1,FLOT2,ATG4D,DOCK4,COG2,FOXJ2,CYB5R2,PANK1,CLSTN1,UTRN,KIF1C,TMEM144,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ITPR3,ASB13,ALCAM,ATP10D,FZD7,ZMPSTE24,AMZ2,DDOST,POPDC3,ACAD10,TRIOBP,SLC27A3,PRR15,CBX7,MAMDC2,PLSCR4,HAPLN3,SLC41A1,CENPI,EPS8,CBLL1,NES,HERC5,PBX3,PLD2,DNAH3,EFNB1,HLA-A,WWP2,SLC25A36,CKAP5,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,FJX1,CCDC82,ERBB3,TTPA,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ALDH2,ARHGEF28,LONRF3,ZC3H11A,PAPD7,TCFL5,ZKSCAN2,FBXO9,DIAPH2,UBAC1,YES1,GRTP1,FOS,KIF11,CDK5RAP1,CRTC2,DCTN6,ACADSB,DGCR2,SEC14L4,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR62,WDR91,FZD5,ESPL1,CXorf56,DEF6,MELK,FAF2,UGT8,UBE2Q1,VARS2,PLAC1,MPP5,ERP29,TRIM68,ECI1,HTR1D,ADPRHL1,ZFYVE16,SIPA1L2,HSF2,CDKL5,ARHGEF37,METTL7A,ANKFN1,CEP78,TRPC1,ASH2L,CTTN,MYRIP,IL1RAP,STK35,LAMP3,ASXL1,LAP3,ITCH,ACBD3,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,MADD,ZNF165,SP6,GLA,RBM43,CHPT1,CAPN1,NR2C2,PCSK5,CD99,LASP1,ARAP3,ZNF395,PPP1R12A,SERPINE2,BVES,PYROXD2,ETV5,ASB9,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,QSOX2,SPP1,TYW3,B3GALNT1,CES2,NOXA1,PFKL,FAM20C,OCRL,COL6A1,MTMR10,PRKCI,SRP54,LIMCH1,BRAT1,C10orf54,NPTN,HLA-C,ZRANB1,GAD1,SLC12A2,CCDC88A,SNED1,TPGS2,ELK3,PODXL2,SPA17,PDE5A,KIAA1109,HEATR5A,NUBP1,C3orf58,RANBP9,RHPN1,SOX13,INSR,UAP1,TMEM30A,SPAG7,SH3BP4,RAB31,DONSON,CTSA,SHROOM2,TMEM14A,JAK3,COL16A1,RARG,AFAP1,DRD1,LMO7,NCKAP5,DYNLRB1,PAX6,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,SAP130,ZNF687,CYP4F11,KIF14,ZBTB49,DIXDC1,EPB41L4B,ETHE1,NFKB2,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,CD40,TMTC2,CDC25C,PDHX,ARHGAP35,SOCS3,HSF4,ALDH5A1,STAT6,SECTM1,PTBP3,RCAN2,SPTBN5,MAD2L1BP,ABCA1,LNP1,GLIS3,GCLM,ENO2,TSPAN15,ARHGEF11,ARHGEF7,SHPRH,SH3D19,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,RBP7,XPR1,HMGXB4,ITGA2B,HDAC9,TMEM63A,SYDE2,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,TOX2,RRBP1,ZDHHC13,ARVCF,KANK2,CLIP2,SLC35A1,RPGR,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,RUNX3,FAM73B,NDRG3,LEPR,FOXL1,LEMD2,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,TRIM69,RAP2C,SPINT2,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,DOC2A,ACACB,ADD1,IL15RA,MRPS15,AASS,TRIM5,DNAJC3,XIAP,CACNA2D2,SMARCAL1,DHX8,NRG2,LGI3,SYTL4,CA8,BARD1,KIF26A,PHF1,EPDR1,CALM2,DAPK2,TP73,ZYX,TGFBR3,RGS12,AP1M2,PQLC2,ARHGAP42,KIAA1107,DNAH6,CYP2S1,CABP1,PPP1R16A,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,ACOX2,PIK3CD,TINAGL1,MANF,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,SERTAD4,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,TRIM47,CAMK2N2,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,LSM14B,ARF6,PDPR,GAB1,E2F8,ALDH6A1,TMTC3,CYP2J2,STRN4,ZNRF3,MERTK,LMNA,ELF3,GNS,DNPEP,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NEK2,NCAM1,EPHX1,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,MEST,SPTLC2,DCP2,RHOB,STK17A,DHX32,PTPRF,SCARB2,NAAA,NCOA3,HTT,SETD3,TEX30,ITPR1,DYSF,AURKA,OSMR,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,TRPC3,ZNF502,RPS6KA3,CSRP2,XDH,EGLN1,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,FAM131C,ACTR8,WDTC1,RGS20,ETNK1,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,ZNF385B,UHRF1BP1L,CCND1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,ARL4D,SCN3A,ENPP4,CAMSAP3,SSH3,PSRC1,LGALS8,FZD4,PLEKHO1,SYNE2,CDCA2,NUSAP1,IRS2,PEX5,STX10,TTC12,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,PDXK,RGS14,ARNT,TTC8,GALK1,FARP1,TAOK2,NKX3-1,TNRC6C,PARP14,MAN1A2,RASSF7,PDIA3,GMCL1,ANO9,PKN1,GSTP1,ETS1,KCNC4,SRPX2,HOXB2,ICAM1,NEO1,PDIA4,CAPN2,DTX3L,CXCL16,ANK1,ADD3,IRAK1,SLC27A6,ANKS1B,FAM160A2,KCNK5,CALD1,ALG13,FDXR,ADAM15,ECI2,MAPK11,AK3,NPTXR,SGCB,ITM2C,TPCN1,TMX1,HCN3,AMOTL2,POU6F1,NUDT8,LCA5,CTNNAL1,FAM160A1,FMN1,RAPGEF2,MFSD2B,GRIN1,PLEKHA7,DBR1,MYEOV,EMP3,SNTB1,CRISPLD2,ABLIM2,TXK,PITX2,DCAF10,GALNT3,KIAA0141,ATXN7L3,ACVRL1,NR1D2,CCDC6,CENPE,FHL1,HMGA1,NUP37,SHOX2,MYL9,UNKL,SIGIRR,TRIM2,AGRN,FAM199X,PPM1J,EPHA4,CUL4B,FHDC1,NDC80,TP53I11,HDAC6,SDC1,PCNA,SHC3,MKRN3,LMAN2L,ELF5,DDHD2,DUSP10,RGS5,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ING1,CD55,HN1L,EZR,TNFAIP8L1,ERP44,ESYT1,FAM212B,ZBTB7B,VCP,DPYSL3,PLCH1,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,GATA2,SPIN4,EXOC8,TMEM8A,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,MRPS33,WDR72,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,G2E3,EPN3,DHDH,MAPKAPK2,COQ10A,PVRL2,H1F0,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,CTBP1,RNF146,FAM45A,NF2,UGP2,UPF3B,FOXM1,XYLT1,DGKA,ZNF28,ERBB2,SLC7A2,CCNL1,FAM198B,LPIN3,C1orf116,CYP26A1,PER2,RAD23A,CDK14,ABRACL,ATP6V0B,SRPX,EFR3A,N4BP3,PLCG2,LHX6,SRR,GYS1,SCN2A,DVL2,GM2A,CPD,SIRT1,TMTC1,CDC20,MYL12A,MYPOP,DNAJC10,DUOX1,ATP1A1,PRRT4,RTN4RL1,PTK7,ADAMTS14,ANXA9,ZBTB6,C1orf43,AIFM3,NDST3,ZC3HC1,CMTM4,MAN2B2,COL9A3,PACSIN2,TRAPPC10,CD63,MACC1,RUSC2,GNE,GABRG2,SELL,PSMD10,NKRF,JAG2,DSE,PPP2R3A,SLC9A2,SIRPA,GBX2,CCDC92,CEP97,MAGEE1,ABCD1,BUB1,KLF9,HEXIM2,SLC45A3,TLE6,FAH,IGDCC4,DLGAP1,HMMR,MLEC,IFITM3,NR3C1,PPARA,CCDC34,TRIM35,CAPNS1,AKAP3,PELI3,FNDC3A,NPDC1,BCAR1,BSDC1,MAPK8IP1,SCRN2,TMEM50B,BANK1,SERPINA1,FAT4,ZNF214,NAT1,NMI,TMC5,CDCA7L,NETO2,PGRMC1,FAM117A,PKD2,ACADM,TBC1D4,DIS3L,SUN1,GAA,PPP4R4,TTC39B,TMEM41B,ATP8A1,KLC2,TAP1,PPFIBP2,PLXNA1,PLA2G16,SLC20A1,ELMOD2,SESN3,CTGF,ELMO2,ZFP36,RGS3,IQCE,PRICKLE3,IL31RA,AOX1,ATRNL1,MTMR11,RCAN3,LAMP2,ORAI2,LOC81691,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,GALNT7,MCFD2,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ULK2,SGPP1,AHRR,SFXN1,KDSR,FAM177A1,PTER,GNPTAB,NKD1,DHTKD1,TMEM8B,TANC2,TRAF5,RTN3,LZTS1,DLAT,DDX58,MRPL44,INPPL1,CDK17,FRMD4A,HLA-E,ADO,CALB2,DGKQ,KIF23,ISYNA1,SLC1A3,NOTCH2,BMP2K,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,BDH1,SORL1,CD70,TNFRSF12A,PIKFYVE,CTSD,RIMS2,EEF1D,DNAI1,FAM69A,DDB2,QSOX1,MFI2,KIAA1841,TBC1D8B,MICB,AMER1,PTPRH,ANO6,PIP4K2C,KCTD20,VEZT,FAM133B,PKM,KDM3A,FBXO10,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,TMEM54,DCK,NAB2,SLC4A3,FGD6,PCDH19,EFNA1,MAP3K5,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,ARMCX3,CEP70,TRIP10,NLRX1,BROX,CAST,SUZ12,IQGAP1,IRX4,RNF182,KCTD12,EGR3,CD274,SNN,NUDT12,MNS1,GNB2,SLC25A35,CYHR1,APLP2,ZNF75D,FAM46A,FICD,TNPO2,CNNM4,DAB2IP,PHKA2,NR2C1,TMBIM1,TBC1D10B,MYO5B,SLC5A11,CDKN2AIP,SEC23A,TMEM43,CAPN6,TEP1,SLC11A2,PRKCQ,C15orf39,AKR1E2,SP4,ZNF469,PRDM11,NIN,OSBPL2,EPHA10,FYN,PPP2R5A,JAK1,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,ZC3H12B,B4GALT3,NR3C2,ATMIN,DENND5B,OTUD5,MRPS9,WASF3,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,JRKL,ATP9A,CDCA3,CCNJL,GPR180,APOBEC3H,SPR,SIX4,LGALS3BP,TMCC3,RND1,SNTA1,C16orf59,FAM111A,PTEN,CENPJ,SGK3,PRC1,ATP8B1,SLC44A2,TAGLN2,CNOT6L,CNPY3,TRIM62,NCOA2,OSGIN1,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,TEF,MPP1,DENND1B,PARP4,C1GALT1C1,LRRC1,GPLD1,NUCB1,RGS9,MAMDC4,CTNS,PRDX3,RCBTB2,AMMECR1,SLC25A40,PGM2L1,CSTF2,GRIN2D,SLC25A38,NCAPG2,CPEB2,OCLN,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,ST13,CPT2,TAF6L,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,MAGOHB,GRHL1,ZCCHC12,DPYSL2,IMPAD1,PHTF1,DLG1,ANKRD12,AKR1B1,KIF22,RAB20,RP2,NFU1,ARNT2,MYH14,SLC39A10,RASGRP1,FGFR1OP2,OLFML2A,ATL1,TDP1,SYNE3,RNF165,ROR1,PTGFRN,ADRBK2,STK17B,TCN2,SEC14L2,EDNRA,MDK,LRRC42,ZNF114,ARHGEF19,FASTKD1,UEVLD,IARS2,TRIM45,CCDC74B,APBA2,RAP1GAP,PSMC1,PPP2R5D,MIIP,CPPED1,GRN,LRRFIP2,PEX6,ASL,ATP6V1E2,SAMD9,PHLPP1,LYSMD4,OTUD1,ZNF432,AIM1L,CA2,LRRN2,EBF4,FXYD5,ZNF692,KNTC1,RFX5,ACAD8,SIMC1,LRIF1,ALS2CL,KDELR1,HP1BP3,PARD3B,OXR1,GYLTL1B,HMG20B,BTN3A2,RNF113A,AMDHD1,EGFR,MUM1L1,GLCE,GNAS,BCAR3,XKRX,FECH,NUDT16,TSC1,SLC6A6,UTP14C,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,KIF12,PROM2,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,ABCG4,MORC4,GMPR,TDRKH,ZMYND10,MICALL2,ARHGEF16,LRRC45,KCTD15,SETDB2,ZDHHC12,FRYL,SMO,TWIST1,APIP,PDIA6,F2R,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,BAG4,TAF5,SLC39A8,IGSF8,ERBB2IP,DUSP4,SNAPC2,KCTD2,DOCK5,BFSP1,BHLHB9,PEX2,CANT1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,PPP2R2D,LIFR,CBX4,CCDC24,ANXA3,CDS2,SORT1,FRMD6,POC1B,JKAMP,LRP4,FAM134A,MIER3,TRMT2B,POMGNT1,IL17RB,IRF2BPL,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,BRD7,HSPA13,IQGAP3,SYPL1,SUN2,ADAM17,DEPDC4,PHLDB3,ASPM,OGDHL,LRRC66,POLD3,SPAG1,MAP1B,KLHL2,HLA-B,PRCP,HNRNPH2,TADA2B,GLB1,GEM,L1CAM,SNPH,ZNF596 |
| 5.926e-05 | -9.73 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | 355 | 79 | 17758 | 2588 |
GAS2L1,CCDC109B,KLK10,TTC39B,NLRX1,TEX2,IL13RA1,SDC1,ELMOD2,CARD10,MXD1,C1orf116,PLS3,AP1M2,ARHGEF37,SLC44A1,SERINC2,ARL4D,EGLN3,ANKRD9,GM2A,ERAP2,TUBA4A,KRT80,NRBF2,OSTM1,EZR,KDELR3,MTRF1L,RAB38,PTGFRN,TRIM7,CASP4,ARF4,TNS4,CARHSP1,HPSE,C19orf66,CORO1C,P4HA2,INPP4B,BMP1,OVOL1,ADAMTS14,NRG1,TANC2,SLC31A2,FBLIM1,IGFBP6,CPEB4,FRMD6,HES2,S100A2,TMCC3,AIM1L,UBE2Q2,KLC3,MAST4,ULBP2,ALS2CL,MYO5A,S100A6,PVRL4,FAM160A1,PLAUR,PIP4K2C,VAMP3,UBE2A,FBXO8,ZDHHC3,STK17A,RAB31,KLK7,PLIN3,SERPINB1,DCBLD1,KLF7,NGEF,EHD1 |
| 5.937e-05 | -9.73 | GSE22886_TH1_VS_TH2_48H_ACT_DN | MSigDB lists | GSE22886_TH1_VS_TH2_48H_ACT_DN | 194 | 49 | 17758 | 2588 |
PLA2G4A,PARP12,UGP2,CHCHD7,TRIM5,HEXB,TRAPPC8,TIPRL,DNAJB9,IL17RB,MARCH8,ACAP2,MGAT1,PHTF1,RPN2,EGLN3,ZMYM1,CASD1,IL10RB,TMED2,CAMK2G,NAGPA,KCNJ12,SH3BGRL,PIK3R1,RNF11,PARP4,VPS4B,PTGER4,SLC11A2,PRKCQ,CAPNS1,RASA1,NMT2,FOXD2,ANKRD10,RGS9,NT5C2,NCOA3,RBM47,GDE1,CDK19,LRIG1,INPP4B,CAB39,PKD2,TTC9,RGS14,RTN3 |
| 5.937e-05 | -9.73 | GSE7852_TREG_VS_TCONV_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_UP | 194 | 49 | 17758 | 2588 |
NCKAP5,CCDC109B,UBASH3B,RALBP1,SDC4,NKRF,TGFBR1,GALM,PHLPP1,NUCB2,REPS1,ITGB8,CAPG,MDFIC,TNFRSF18,TSPAN13,AK3,LMAN1,FAR1,ITM2C,TIAM1,NEB,MGAT5,FAH,ABCC1,SOCS5,CPD,ERMP1,ELK3,TNIP1,B9D2,MAPKAPK3,CORO2A,SH3BGRL,KIF13A,DUSP4,PRKRA,PCTP,CD83,MAPKAPK2,MAGED2,ENDOD1,SWAP70,ANKRD6,MATN2,SH3BGRL2,SP6,NDFIP1,CD81 |
| 5.937e-05 | -9.73 | GSE7764_NKCELL_VS_SPLENOCYTE_UP | MSigDB lists | GSE7764_NKCELL_VS_SPLENOCYTE_UP | 194 | 49 | 17758 | 2588 |
PLSCR4,RUNX2,PPM1J,JKAMP,UBASH3B,ELOVL7,ERI2,ZNRF3,BAIAP3,FAM81A,IL18R1,TRIM68,KCTD9,SYTL2,CAPN2,RNF128,SNX18,PLEKHF1,DAB2IP,C10orf54,TMEM37,PIM1,C8orf58,RAB27B,PTPRE,SPRY2,MGAT5,C9orf9,MMD,PLSCR1,CASP9,PTGER4,RUNX3,ATP1B1,YES1,SP4,TXK,DCTN6,KLF12,PLOD2,CDCA7L,C1orf21,ABCB1,CAB39,GEM,TTC39C,FZD5,ARSB,CHPT1 |
| 5.937e-05 | -9.73 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN | 194 | 49 | 17758 | 2588 |
PNISR,PINK1,ADD1,CAST,HLA-E,ZCCHC24,CNOT8,INPP5D,ETV5,HEXB,KCTD12,TGOLN2,ITPR2,MGST2,CRABP2,ERP29,PDIA4,CES2,METTL7A,IQCE,PLCG2,RUNDC3B,DAPK1,KCNS3,H2AFY,AHCY,NPTN,CLIP2,ALDH3A2,SMAGP,CTNNAL1,S100A4,CORO2A,LOXL2,IDH1,USP6,SERTAD2,STX10,RCBTB2,SCG2,RAB11FIP2,PRCP,PLA2G15,PNPLA6,ZMIZ1,SEMA3A,NRGN,MAPK12,ABCG1 |
| 5.937e-05 | -9.73 | GSE360_DC_VS_MAC_T_GONDII_DN | MSigDB lists | GSE360_DC_VS_MAC_T_GONDII_DN | 194 | 49 | 17758 | 2588 |
PINK1,ENO2,HLA-E,NDRG1,TSC22D3,CNOT8,ITGA6,GNAL,CALM3,KCTD12,CRABP2,MERTK,REPS1,LMNA,PDIA4,CALM2,RPS6KA2,ITGA3,METTL7A,MCF2L,RUNDC3B,SORL1,H2AFY,MANF,NOTCH3,CPE,CKAP4,TIMP2,TESK1,S100A4,CALM1,BNIP3L,CDA,BCL7B,FOS,ALDH3B1,FYN,RND3,SCG2,RCBTB2,PLA2G15,ZNF165,GDF11,GEM,ZMIZ1,LTA4H,USF2,SEMA3A,ABCG1 |
| 5.961e-05 | -9.73 | hematopoietic or lymphoid organ development | biological process | GO:0048534 | 569 | 119 | 16441 | 2455 |
CASP3,ADD1,HOXB7,EPAS1,IL15,LFNG,THRA,RET,TP53,GATA3,FLT3,CACNB4,PDGFB,TNFSF9,SPTB,TGFBR3,CTNNB1,ARTN,LMO4,PLCG2,MITF,IL31RA,TMEM143,BCL6,RTKN2,ASH2L,PIK3CD,NFKB2,SNX10,TIPARP,SOD1,LGALS8,OSTM1,DMTN,CASP9,NFE2L1,PTGER4,CR2,SLC11A2,GLO1,PYGO1,ANLN,FZD7,CMTM7,SFXN1,STAT6,TBX1,HOXA9,AXL,PTBP3,DHTKD1,RPL22,F2RL1,KLF2,DYRK3,RUNX2,TNRC6C,CDKN1C,BVES,ARHGEF7,TGFBR1,JAG2,NOTCH2,PKN1,HERC6,MERTK,IL18R1,SIX4,HDAC9,SGPL1,MECOM,TOP2A,CD109,RB1,FAM20C,GATA2,GPC3,BAX,MSH2,FNIP1,ERCC2,WNT3A,RAG1,CITED2,GFI1,SYK,FARP2,HES1,ADAM17,RHOA,WNT10B,CRIP2,PIK3R1,RC3H2,TTC7A,RUNX3,EIF2AK1,FOXL1,TXK,FAS,PITX2,FECH,CD8A,ONECUT1,TSC1,FGFR2,TWSG1,PRDX3,DHRS2,CSF1,PPP2R3C,LRRK1,FZD5,JAK3,CCNB2,SLC25A38,MELK,JARID2,IRF1 |
| 5.976e-05 | -9.73 | Antigen Presentation: Folding, assembly and peptide loading of class I MHC | REACTOME pathways | R-HSA-983170 | 24 | 12 | 8202 | 1235 |
CALR,HLA-B,SEC23A,TAPBP,HLA-E,HLA-F,TAP1,ERAP1,PDIA3,HLA-C,HLA-A,ERAP2 |
| 6.179e-05 | -9.69 | GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP | 184 | 47 | 17758 | 2588 |
BIN1,ENO2,FAM169A,GALNT12,RASA2,ITGA6,DGKA,NUCB2,TRIB2,AIP,LTBP3,DENND2D,TMEM63A,OXCT1,MGAT4A,DDHD2,PASK,MSH2,FAM102A,MYLIP,MPHOSPH9,ASXL1,SYNE2,COX11,PRKCQ,YES1,ITPR3,KDM3A,SESN1,PLEKHB1,TXK,PLCG1,MPRIP,LDLRAP1,NGFRAP1,AMMECR1,LRIG1,INPP4B,APPL2,TMEM14A,TBC1D4,TRAF5,SLC25A38,NR3C2,PKIA,FAM134B,DOCK9 |
| 6.179e-05 | -9.69 | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | 184 | 47 | 17758 | 2588 |
ARHGEF3,CDK17,TTC39B,IBTK,TUBB4B,CAST,MAN1A2,ITGA6,ETNK1,FAM91A1,ETS1,PGAP1,ADD3,KLF3,RUNDC3B,ANKRD12,MDFIC,TMEM64,WBP4,CNOT6L,CITED2,LRIF1,CPE,ATP2B1,FAM69A,ELK3,B3GNT2,NR3C1,STAT4,PIK3R1,HEATR5A,SESN1,CNOT2,DCTN6,NCOA3,CDK19,SLC35B3,LRIG1,FAM3C,SLC25A40,INPP4B,NFKBIZ,MAP3K5,LTA4H,GLCCI1,F2RL1,JARID2 |
| 6.185e-05 | -9.69 | developmental maturation | biological process | GO:0021700 | 195 | 50 | 16441 | 2455 |
KLF2,RUNX2,AGRN,CDKN1C,EPAS1,IL15,CD63,RET,GATA3,PHOSPHO1,CNTNAP2,SEPT4,CCNB1,PRKACA,PICK1,RND1,BMP2,RB1,RPS6KA2,CTNNB1,PTEN,FAM20C,GATA2,LHX6,NTN4,ERCC2,FARP2,REC8,CLCN3,HES1,RHOA,ANO6,DCHS1,GRIN1,SYP,RAB38,DAG1,CDK5R1,FAT4,BFSP1,SEMA4D,ACVRL1,AXL,PTBP3,NR4A2,HOXB13,GDF11,FZD5,SOX8,FOXA1 |
| 6.216e-05 | -9.69 | Thioredoxin | pfam domains | PF00085 | 31 | 14 | 16629 | 2504 |
QSOX1,DNAJC10,TXN,P4HB,TMX4,PDIA5,PDIA3,TXNDC9,ERP44,PDIA6,TXNDC11,QSOX2,TMX1,PDIA4 |
| 6.240e-05 | -9.68 | meninges-meningioma-atypical | COSMIC cancer mutations | meninges-meningioma-atypical | 15 | 9 | 17775 | 2585 |
CDKN2C,NF2,CTNNB1,AKT1,PTEN,SMO,PIK3CA,IDH1,EGFR |
| 6.307e-05 | -9.67 | BOQUEST_STEM_CELL_DN | MSigDB lists | BOQUEST_STEM_CELL_DN | 210 | 52 | 17758 | 2588 |
ANXA3,ARAP3,KIAA1462,SSH1,HOXB7,IL15,HLA-F,ITGA6,CCDC68,RASGRP3,F11R,JAG2,MGST2,PHLDA1,IL18R1,TSPAN7,CARD10,RND1,MYO5C,MECOM,CARD8,RPS6KA2,GATA2,TSPAN6,MCF2L,LHX6,TACSTD2,TSPAN13,HLA-C,EPHB4,KANK3,PTPRE,MAST4,MYRIP,SMAGP,ENPP4,MCTP1,SYBU,SPTLC2,CDK1,KLHL2,BCAR3,HLA-B,SLCO4A1,SWAP70,ETS2,AREG,PIK3C2B,EFNA1,IFIH1,ABCG1,DOCK9 |
| 6.355e-05 | -9.66 | endosome membrane | cellular component | GO:0010008 | 392 | 86 | 17570 | 2579 |
LAMP1,NDRG1,EPHA4,RET,ERBB2,MVB12B,ZFYVE9,SLC9A7,ZFYVE16,RAB15,ATP6V0B,ACAP2,TM9SF2,WDR44,STEAP2,ABCA2,SNX16,STEAP3,ECE1,MARCH2,RAB27B,SNX10,TMEM9,TMBIM1,LAMP2,SNX8,VPS11,CLCN3,KREMEN2,VPS4B,AP5M1,SLC11A2,KIF13A,WIPI1,SLC9A6,IRF7,CHMP4B,ARF6,STARD3NL,SORT1,PACSIN2,GOLIM4,GGA1,CD63,TAB3,BACE1,HLA-F,HLA-E,TMEM55B,ATP9A,RAB23,FAM21C,HLA-A,VPS26A,PARM1,MARCH8,SNX13,IRAK1,SNX18,ZNRF2,OCRL,KIAA0319,PLEKHF1,HLA-C,MAP3K7,WNT3A,PIKFYVE,TPCN1,SUN2,MMD,IFITM3,ANTXR1,STEAP1,CPTP,EGFR,RHOB,HLA-B,INSR,RAB11FIP2,RAP2C,APPL2,PLD1,FZD5,PLIN3,NDFIP1,EHD1 |
| 6.398e-05 | -9.66 | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | 1176 | 218 | 17758 | 2588 |
CCNI,TXN,ADD1,TSC22D3,GATA3,CAMK1D,SLC20A1,PIGL,CMTM6,FANCI,ZNF275,WEE1,CYP1A1,LRRC6,CTGF,CABP1,FOSB,AOX1,DUSP10,TUBG1,TNFRSF18,RGS5,PIK3CD,PXMP4,TIPARP,FGFR1OP2,CCDC38,CERS2,ORAI2,VPS11,TRIM8,CENPA,ITCH,ARHGDIB,SLC17A5,AURKB,F12,ZFAND5,IDH1,SESN1,RHEB,PLEKHB1,SGPP1,LRRC42,TMEM164,PLEKHG6,TBC1D17,RBM47,SH2D3C,MADD,MAP3K11,CAB39,EIF4EBP2,SP6,ARF6,WBSCR27,PSMC1,NXT2,RMND5A,CDK17,KIF23,DHRS3,TNFRSF19,PRRG4,PAIP2B,ZNRF2,KCNN4,SLC16A6,ATP5H,FAM13B,RUNDC3B,SRP54,OSTF1,NPTN,C10orf54,ACAD8,PIKFYVE,ALDH3A2,HP1BP3,FAM69A,PAQR7,GFPT1,DDB2,MRPS33,B9D2,MAPKAPK3,ADCK3,SHARPIN,SPA17,PYGL,VEZT,AMDHD1,GLT8D2,RHOB,C18orf8,NCOA3,MTFMT,DCK,TMEM30A,MPP2,FGD6,MDH1,NIPA1,RPS6KA3,EGLN1,DMPK,ELK4,ARHGAP11A,TPRN,LZTFL1,SLC25A24,AVPI1,KCNAB3,NF2,TUBB4B,SLC2A8,PTTG1,DGKA,TP53,TESK2,FTH1,NUF2,CD274,GRK6,PCBP1,MNS1,SYTL2,APLP2,KHNYN,WDR44,CDKN1B,ACSL4,ARL4D,CDKN2D,TBC1D10B,SEPHS1,CPD,SIRT1,MBP,ERLEC1,LGALS8,SEPT6,SERTAD3,COX11,IGSF8,GTF2A2,KCTD2,SNX12,ATP10D,FZD7,ZMPSTE24,AMZ2,FYN,PTPRJ,PPP2R5A,CDK19,ABHD12,RBL1,STAT6,PPP1CB,ANXA9,DMWD,C1orf43,RGS14,GEN1,KDELC2,CTDSP1,PRKAR1A,OTUD5,HSP90B1,DAP,FAM134A,ARL4C,ERI2,ETS1,LBR,AKIRIN1,KIF5B,SLC25A45,RNF128,FAM160A2,TMEM62,SLC35B4,FAM63A,IL17RA,H2AFY,PLEKHF1,CNOT6L,RAG1,CITED2,FAM134C,MSH6,HMMR,ACBD5,SYPL1,OPLAH,MLEC,RHOA,ZWINT,DENND1B,LRRC66,DBR1,EMP3,YES1,KIF11,BCL10,CNOT2,LDLRAP1,SLC25A40,NMI,FAM117A,ERAP1,SSNA1,ETAA1,ITGAV,ARSB,NDFIP1,JARID2 |
| 6.404e-05 | -9.66 | BAKKER_FOXO3_TARGETS_UP | MSigDB lists | BAKKER_FOXO3_TARGETS_UP | 60 | 21 | 17758 | 2588 |
PINK1,NF2,CPEB4,DSTN,ASAH1,CR2,DUSP4,SEPP1,SESN1,SIRPA,BTG1,IGF1R,PNPLA6,PGM2L1,CDKN1B,ATP1B3,NCEH1,CITED2,GLCCI1,TMX1,DENND5B |
| 6.451e-05 | -9.65 | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | 169 | 44 | 17758 | 2588 |
MAN2B2,KLF2,TRAPPC10,DNAJC3,ITGA6,EPHA4,TMX4,HABP4,PDCL,SELL,ASAH1,SNN,TRIB2,FAM46C,MECOM,MARCH8,OTUD1,FBXO7,SORL1,SGK1,PIM1,MARCH2,ZRANB1,CITED2,DUSP1,RNF11,PRKCQ,FOS,RASGRP2,TXK,IRS2,PTGS2,SCARB2,NAAA,PTPRJ,COQ10A,PELI2,WDR19,CSGALNACT1,YOD1,NR4A2,NFKBIZ,MAP3K5,EPB41L4A |
| 6.461e-05 | -9.65 | regulation of metabolic process | biological process | GO:0019222 | 6593 | 1071 | 16441 | 2455 |
IBTK,GRIK2,PNPLA2,HEXB,RET,SNX9,CARD10,GRM5,ZNF275,NPM2,CDKN2C,DNM2,CRY2,PPP1CA,TIAM1,TIPARP,NEK4,UXT,CDA,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,TRAF3IP1,NOD2,HDAC1,RNASEL,HSPB1,STARD13,ZNF720,GGA1,ITGA6,RAB23,GPSM2,MARCH8,TFAP4,FLII,RAC2,PAIP2B,MEGF8,FBXO7,RANBP1,MAP3K9,USP38,USP1,MYDGF,MAPK7,MYLIP,NUP85,PHKG2,PPP6R1,MAPKAPK3,PYM1,FHL2,ELK1,NPHP3,PSMA4,PLIN5,FNTA,ETS2,STK39,GDF11,CBX5,NUP58,TMEM173,DOCK9,DMPK,NQO1,INPP5D,PTTG1,MGST2,ST5,CDH1,SH3BP1,TAX1BP3,DLG3,RASGEF1A,MYT1,ETV4,RIPK2,APOBEC3D,PFKFB2,HTATIP2,GTF2A2,SNX12,ZNF618,EBF2,NFIX,CCNB3,CORO1C,WFS1,MAPK12,HSP90B1,CKAP2,TRAF2,ESRP1,SDC4,HABP4,FLOT1,CTSZ,ZNF219,NFAT5,CTNNBIP1,DIRAS3,ZFX,PDCD10,ITGB8,KNDC1,GPC3,CST3,BAX,RAG1,MED22,PLSCR1,PIK3R1,NUB1,PGBD1,RAB3IP,LDLRAP1,NR4A3,ITGAV,OSR1,CD81,SRSF9,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,DNAJB11,F11R,NENF,ITPR2,SPTB,FANCI,TFAP2E,RPS6KA2,NUP210,CTNNB1,RABEP2,NPNT,IL6ST,ARL1,PSMC2,MITF,PASK,ABCA2,PLK1,THRB,KCNIP3,CELSR2,CBX6,NFE2L1,EAF2,KDM4D,PLEKHG6,KLF12,ZNF367,HOXA9,KLF11,KPNA2,TC2N,RRAGD,RUNX2,LMTK3,DNAJB2,FXYD3,RASA2,PDCL,PSMD7,SORBS3,HES2,FBLN1,TIMP1,RINL,TBCD,PIM1,WNT3A,USP31,RGMB,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,CDK5R1,FOXD2,RASGRP2,NLRC5,CDAN1,USP43,RAD21,HOXB7,CTDSPL,TP53,P2RX7,BAHD1,STIL,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,KMT5C,LMO4,PPME1,BCL6,CDH3,NOTCH3,OAS3,TMEM64,CTDSP2,PPIF,CLCN3,ERLEC1,AKT1,SERTAD3,ACO1,C3orf33,DAG1,PTGS2,ZNF628,PTPRJ,IDE,RBL1,MMP17,STK38,CHMP4B,EFNA5,IRF7,ARHGAP4,ARFGEF3,CTDSP1,PINK1,CPEB4,TAB3,CTSB,GNAL,GTF3A,GDF15,HMGN3,AIP,PARM1,FZD6,SH2D4A,ZDHHC21,CD109,FOXP2,GTF2F2,UBE2J1,TFAP2A,SGK1,TRIM21,SYK,DUSP1,WBP5,NFE2L3,P2RX4,HES1,FBLN5,RHOA,HMGN5,PLAUR,PRICKLE1,STMN3,MAML2,COL7A1,BBS2,USP6,BCL10,CNOT2,DDAH1,FGF18,E2F1,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,TXN,SSH1,LGR4,TSC22D3,CUL1,PSME1,CAMK1D,SEPT4,PICK1,PAK6,HELZ2,ZNF823,FOSB,SERINC2,PIK3CA,IRF2,ZBTB18,ACVR1C,CDYL,BNIP3L,LDB2,POR,SH2D3C,PPP2R4,PRDM5,NFKBIZ,SERPINI1,MAPK13,SPRY4,F2RL1,FGD1,CDKN1C,SCOC,TBC1D1,PRKAA1,AKAP17A,APBA1,PSIP1,SH3RF2,CALR,RALGPS2,BHLHE41,PPP4R1,MSH2,DAPK1,PRKG1,DLX4,ZNF117,GPR161,SOCS5,TRAK2,GFPT1,CALM1,WHSC1,NPC2,EPHA1,NFIB,MMP15,AP1AR,PELI2,PIAS2,ARAP1,FAM83D,SFMBT1,SAMD8,CABIN1,ZBTB34,PER3,SPRED1,FOXO6,TCF25,DLGAP5,THRA,RALBP1,BCL2L1,FLT3,EPM2A,EPS8L2,CD46,NOV,CCNA2,ACAP2,RALB,PDE4D,OSBPL7,FLOT2,MED30,DOCK4,FOXJ2,DRAP1,ATP1B1,RAD17,PYGO1,PKMYT1,CBL,ITPR3,FZD7,NGFRAP1,CBX7,PRKAR1A,DEPDC1,NES,HERC5,PBX3,FGF19,WWP2,SCML1,E2F7,RNF128,DRAM1,ERBB3,CITED2,MSH6,FARP2,PDGFC,TGIF1,ARHGEF28,TCFL5,ZKSCAN2,YES1,GRTP1,FOS,CRTC2,CDK5RAP1,TIMP3,FGFR2,RIN3,TBX18,RYK,LRRK1,FZD5,ESPL1,RGMA,CCNC,FAF2,CRYM,VARS2,COMMD5,MAP1LC3B,ERP29,ZFYVE16,EPCAM,SIPA1L2,HSF2,CDKL5,ARHGEF37,SIVA1,ASH2L,CTTN,SP5,CYP1B1,CXXC5,ASXL1,ITCH,USP18,ARHGDIB,TYSND1,GPRC5B,MADD,TDRD7,CAB39,ZNF165,SP6,GLA,NR2C2,ARAP3,PPP1R2,SERPINE2,ZNF395,PPP1R12A,BVES,ETV5,ASB9,CALM3,TEC,DUSP5,NOXA1,FAM20C,OCRL,SUCO,PRKCI,BRAT1,NPTN,C10orf54,ETV7,CCDC88A,MDFI,ELK3,PDE5A,RANBP9,RHPN1,SOX13,INSR,SH3BP4,DCUN1D1,CTSA,JAK3,TOB1,RARG,DRD1,CCNE2,SORBS1,PAX6,HDAC11,SOD2,IL27RA,OSR2,MXD1,SAP130,ZNF687,KIF14,ZBTB49,ECE1,EPB41L4B,NFKB2,UPF3A,CKS2,CHP1,SOAT1,RFK,GLO1,CD40,CDC25C,PDHX,ARHGAP35,SOCS3,JADE1,HSF4,STAT6,TLE1,PTBP3,SPTBN5,RCAN2,ABCA1,GLIS3,GCLM,ARHGEF11,SH3D19,ARHGEF7,SERPINB9,TGFBR1,TRIB2,SBF1,HMGXB4,HDAC9,SYDE2,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,ACTA2,H2AFY,KANK2,RPGR,DCAF6,WNT10B,RC3H2,RGCC,RUNX3,TCEAL8,LEPR,FOXL1,LEMD2,ARHGAP24,CASP7,SWAP70,SPINT2,RAP2C,ARRB1,ZMIZ1,AHR,RAB3IL1,ABCG1,NGEF,ACACB,TRIM24,TRIM5,DNAJC3,SMARCAL1,FBXO2,XIAP,NRG2,IL18,MORF4L2,BARD1,PHF1,DAPK2,CALM2,TP73,TGFBR3,RGS12,PSMD1,ARHGAP42,CABP1,KLF3,PPP1R16A,PIK3CD,APOBEC3G,VPS11,SMARCA2,TNIP1,SPRTN,F12,LOXL2,PPP1R14C,CAMK2N2,ANKRD6,DNM1L,LIMK1,MAP3K11,AGFG2,SERPINB6,LSM14B,GAB1,PDPR,E2F8,HOXC13,TMTC3,NUAK1,SOX9,LMNA,ELF3,FAM13B,NEK2,NCAM1,SALL4,STAT4,MYBL2,CALCRL,ILK,TP53INP2,DCP2,STK17A,NCOA3,SEMA4D,HTT,SETD3,ITPR1,AURKA,ZNF502,SERPINB1,RPS6KA3,EGLN1,XDH,ARHGAP11A,GRHL2,ACTR8,RGS20,WDTC1,PRKACA,APC2,CCND1,SP100,DACT1,CDKN2D,RNF169,CAMSAP3,PSRC1,FZD4,NRBF2,CDCA2,PXYLP1,IRS2,WWTR1,SIPA1L1,PLEKHG1,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,FARP1,RBM24,PARP14,GMCL1,PKN1,ARHGEF40,GSTP1,ETS1,HOXB2,TIPRL,SRPX2,ICAM1,NEO1,IRAK1,CTSC,MCF2L,TMBIM6,PLEKHF1,WWP1,MAPK11,ZNF230,CRTAP,POU6F1,BCL9,RAPGEF2,EIF5A2,GRIN1,ABLIM2,TXK,PITX2,BTG1,KIAA0141,ACVRL1,NR1D2,ATXN7L3,ZFP30,ARFGAP3,HMGA1,CENPE,NUP37,SHOX2,USF2,FOXA1,SIGIRR,AGRN,CUL4B,EPHA4,SUDS3,HDAC6,PDGFB,PCNA,SHC3,ELF5,DUSP10,TNFRSF18,RGS5,MYBL1,ZNF462,PCGF5,CD55,CITED4,C12orf65,EZR,PRKRA,IDH1,ZBTB7B,CDK1,VCP,OPTN,IRX3,TBC1D17,PRKCDBP,CTNND1,MAFF,PRKAA2,UBASH3B,RACGAP1,DOCK11,BMP2,RB1,DAZAP1,IGF1R,GATA2,PAK2,MDFIC,PLCB2,PSMA5,SPATA13,TCF7,EIF2AK1,MAPKAPK2,CSF1,ATP1B3,CTBP1,IFI6,AVPI1,UPF3B,NF2,FOXM1,ERBB2,ZNF28,RASGRP3,CCNL1,LPIN3,PER2,RAD23A,LHX6,PLCG2,EGLN3,GM2A,DVL2,CTH,SIRT1,TIMP2,TCEB2,FIGNL1,CDC20,MYPOP,DNAJC10,ATP1A1,PSMD3,ZBTB6,ZNF701,CNEP1R1,MACC1,CD63,DAP,PSMD10,NKRF,CRABP2,PPP2R3A,GBX2,SLC35B4,BUB1,KLF9,HEXIM2,TLE6,CAMK2G,PSMB4,IFITM3,NR3C1,PPARA,LITAF,FXR2,MAPK8IP1,BANK1,SERPINA1,TWSG1,ZNF214,CDCA7L,NMI,PKD2,PPP2R3C,TBC1D4,UBE2C,NDFIP1,ACVR1,PPP4R4,GATA3,CCNB1,RIC1,ELMOD2,CTGF,RGS3,ZFP36,IL31RA,RCAN3,PBK,CASP9,AGO4,AURKB,PIF1,SAV1,ULK2,ARHGEF26,AHRR,HLF,AREG,TBX1,PLK2,NKD1,EIF4EBP2,TRAF5,LZTS1,DLAT,DDX58,KLF2,INPPL1,DGKQ,NOTCH2,BMP2K,MECOM,ITGA3,CYR61,SNX18,NECAB3,SORL1,PIKFYVE,TMED2,RIMS2,EEF1D,EPB41L5,QSOX1,MFI2,ZNF84,MMD,TBC1D8B,PIP4K2C,KCTD20,CYFIP2,KDM3A,RASA1,FAS,PRKAG2,SERTAD2,NAB2,TCEAL4,FGD6,NR4A2,EFNA1,MAP3K5,IRF1,ELK4,PLEKHG3,ARMCX3,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,IRX4,EGR3,APLP2,ZNF75D,FAM46A,FICD,CDKN1B,DAB2IP,IFIT1,NR2C1,TMBIM1,TBC1D10B,DMTN,COX11,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,FYN,ZNF641,PPP2R5A,JAK1,STK26,STAT1,KIAA1804,PPP1CB,SLC27A1,NRG1,KLF5,NR3C2,ATMIN,DENND5B,PCOLCE,ARHGEF3,APOBEC3H,SPR,SIX4,TEAD3,SNTA1,PPP1R10,PTEN,SGK3,ATP8B1,ERCC2,MAP3K7,CNOT6L,GFI1,SPRY2,TRIM62,NCOA2,RASGRF1,CASK,ARAP2,TEF,DENND1B,VAMP3,FURIN,GPLD1,RGS9,PRDX3,RCBTB2,SERPINB5,GRIN2D,GPER1,CPEB2,USP16,JARID2,EMX1,CASP3,ST13,CAMKK1,TAF6L,DENND2D,ARHGEF10L,GRHL1,ZCCHC12,PHTF1,DLG1,RP2,ARNT2,SLC39A10,RASGRP1,SOD1,TRIM8,ASCL5,EDNRA,SEC14L2,MDK,NEIL1,ARHGEF19,ZNF114,IARS2,ADIPOR1,RAP1GAP,APBA2,PPP2R5D,PSMC1,PIFO,PHLPP1,ZNF432,EBF4,FNIP1,ZNF692,RFX5,ACAD8,LRIF1,ALS2CL,HP1BP3,FBXO8,HMG20B,EGFR,BCAR3,GNAS,FECH,ONECUT1,TSC1,NUDT16,PLPP3,NFKBIA,YOD1,PROM2,KLF7,GAS2L1,IL15,PSME2,TDRKH,PATL2,ARHGEF16,SS18,SVBP,SETDB2,FRYL,SMO,TWIST1,APIP,F2R,HSPA2,FRS3,MAP3K3,ZNF525,TAF5,BAG4,ERBB2IP,DUSP4,SNAPC2,DOCK5,MAP3K6,PEX2,OVOL1,AKNA,PPP2R2D,CBX4,ANXA3,SORT1,LRP4,MIER3,AES,ZNF212,IRF2BPL,SNX13,ADORA1,BRD7,CKS1B,MXD3,IQGAP3,ADAM17,NR4A1,GCLC,MBNL3,MPV17L2,PRCP,UBE2D2,TADA2B,HOXB13,SOX8,ZNF596 |
| 6.490e-05 | -9.64 | kinase inhibitor activity | molecular function | GO:0019210 | 59 | 21 | 16491 | 2452 |
CASP3,SPRED1,CDKN1C,IBTK,DNAJC3,PRKAR2B,TRIB2,MAPK8IP1,SOCS3,CDKN2C,CAMK2N2,PRKAG2,H2AFY,CDKN1B,HEXIM2,HSPB1,CDKN2D,SPRY2,PKIA,PRKAR1A,CHP1 |
| 6.525e-05 | -9.64 | DAZARD_UV_RESPONSE_CLUSTER_G6 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G6 | 144 | 39 | 17758 | 2588 |
EXPH5,PPP1R12A,ARHGEF7,GNE,TMX4,CUL1,KIF23,PHLPP1,CCNB1,APPBP2,SLC25A36,TOP2A,FRYL,KIF14,ATP13A3,PIKFYVE,MAST4,ATP2B1,SMC4,DOCK4,CENPA,NR3C1,MICB,CDYL,FNDC3A,POLD3,KIF11,USP6,LRRC42,CNOT2,FYN,FGFR2,SLC9A6,ZMIZ1,MAP3K5,CCNB2,KLF7,JARID2,DOCK9 |
| 6.542e-05 | -9.63 | PYROPHOSPHATASE_ACTIVITY | MSigDB lists | PYROPHOSPHATASE_ACTIVITY | 226 | 55 | 17758 | 2588 |
RECQL,PEX6,RALBP1,GNAL,ARL4C,SMARCAL1,ABCG2,DHX8,MRAS,RAB6A,SEPT4,GNB2,PICK1,ABCD4,TOP2A,DIRAS3,RAC2,ENTPD4,ARL1,MSH2,ABCA2,ATP8B1,RAB27B,ARL4D,MSH6,ATP2B1,ABCC1,RAB3B,RHOA,VPS4B,KIF20B,ARFRP1,PIF1,ATP1B1,GNA11,RHEB,VCP,RHOB,ARF4,DDX23,GNAS,TAPBP,ENPP1,ATP1A1,DNM1L,RND3,DOLPP1,ATP7B,PPP2R4,RAB31,ATP1B3,ATP6V1C1,ARF6,PSMC1,ABCG1 |
| 6.567e-05 | -9.63 | TAP binding | molecular function | GO:0046977 | 7 | 6 | 16491 | 2452 |
HLA-B,TAPBP,HLA-C,HLA-F,HLA-A,TAP1 |
| 6.575e-05 | -9.63 | Signaling by Insulin receptor | REACTOME pathways | R-HSA-74752 | 304 | 71 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,DUSP4,RHEB,IRS2,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,CAB39,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,ATP6V1E2,CALM3,PSMD10,FGF19,DUSP5,ITGA2B,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,PSMA4,RASA1,EGFR,TSC1,PRKAG2,INSR,FGFR2,FGF18,ARRB1,GRIN2D,ATP6V1C1,JAK3 |
| 6.699e-05 | -9.61 | Semaphorin interactions | REACTOME pathways | R-HSA-373755 | 67 | 23 | 8202 | 1235 |
MYL9,DPYSL5,RHOA,ARHGEF11,ERBB2,PLXNA1,DPYSL4,RHOB,CDK5R1,RND1,DPYSL3,ARHGAP35,RAC2,FYN,SEMA4D,DPYSL2,LIMK1,PAK2,PLXND1,MYH14,SEMA3A,MYL12B,FARP2 |
| 6.735e-05 | -9.61 | cell cycle G2/M phase transition | biological process | GO:0044839 | 141 | 39 | 16441 | 2455 |
USH1C,CEP70,PPP1R12A,FOXM1,TUBB4B,NES,CUL1,CCNB1,PRKACA,CKAP5,CDK14,WEE1,CCNA2,CNTRL,CENPJ,CEP78,TUBGCP6,NEK2,PLK4,DNM2,TUBG1,TUBA4A,PLK1,WNT10B,MYBL2,PRKAR2B,PKMYT1,CDC25C,BORA,CDK1,OPTN,ABCB1,PPP1CB,AURKA,SSNA1,CEP41,NDE1,CCNB2,MELK |
| 6.735e-05 | -9.61 | G2/M transition of mitotic cell cycle | biological process | GO:0000086 | 141 | 39 | 16441 | 2455 |
USH1C,CEP70,PPP1R12A,FOXM1,TUBB4B,NES,CUL1,CCNB1,PRKACA,CKAP5,CDK14,WEE1,CCNA2,CNTRL,CENPJ,CEP78,TUBGCP6,NEK2,PLK4,DNM2,TUBG1,TUBA4A,PLK1,WNT10B,MYBL2,PRKAR2B,PKMYT1,CDC25C,BORA,CDK1,OPTN,ABCB1,PPP1CB,AURKA,SSNA1,CEP41,NDE1,CCNB2,MELK |
| 6.749e-05 | -9.60 | VEGFR2 mediated cell proliferation | REACTOME pathways | R-HSA-5218921 | 241 | 59 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,ITPR2,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,ITPR3,PSMA4,RASA1,EGFR,IRS2,PLCG1,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,ITPR1,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 6.826e-05 | -9.59 | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | MSigDB lists | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 195 | 49 | 17758 | 2588 |
MYL9,CTHRC1,PCOLCE,ENO2,SERPINE2,IL15,SDC4,NOTCH2,SDC1,FBLN1,SPP1,TGFBR3,CTGF,TIMP1,CYR61,MAGEE1,CALD1,CAPG,ACTA2,TNFRSF12A,IGFBP2,SGCB,LOXL1,QSOX1,FBLN5,COL6A2,PLAUR,SAT1,EMP3,COL7A1,LOXL2,MEST,SNTB1,RHOB,COL12A1,DPYSL3,FAS,FUCA1,TIMP3,AREG,SCG2,PLOD2,MYLK,MATN2,BMP1,ITGAV,GEM,PLOD3,COL16A1 |
| 6.847e-05 | -9.59 | BENPORATH_ES_1 | MSigDB lists | BENPORATH_ES_1 | 362 | 80 | 17758 | 2588 |
CASP3,PNISR,SPC25,UGP2,TRIM24,DLGAP5,LGR4,TUBB4B,AASS,PTTG1,ERBB2,KIF2C,CCNB1,PLA2G16,CYP26A1,EPCAM,SCNN1A,AP1M2,CCNA2,CYP2S1,PASK,KCNS3,EPB41L4B,SLC39A10,EGLN3,DLG3,ETV4,SEPHS1,SIRT1,KIFC2,LGALS8,CDC20,AURKB,ITPR3,CDK1,GINS4,FZD7,PRIM1,GPRC5B,GNPTAB,LRIG1,KPNA2,SPRY4,COBL,ESRP1,ERCC6L,CNTNAP2,CRABP2,PSIP1,M6PR,AKIRIN1,CTSC,MSH2,SORL1,BUB1,GAD1,MSH6,TMX1,NFE2L3,HMMR,RAB3B,PCDH1,HPS3,SALL4,MICB,MRS2,GYLTL1B,DIAPH2,EPHA1,CACHD1,PROM1,FAM64A,CDCA5,MAL2,HMGA1,FZD5,NUP37,NCAPG2,CBX5,JARID2 |
| 6.857e-05 | -9.59 | KANNAN_TP53_TARGETS_UP | MSigDB lists | KANNAN_TP53_TARGETS_UP | 56 | 20 | 17758 | 2588 |
QSOX1,DDB2,IGFBP6,DCAF7,DGKA,FHL2,GDF15,SCRIB,EXT2,SPAG1,FAS,MARCH8,PCNA,CES2,BCL6,TAX1BP3,ACTA2,LOXL1,CTDSP2,DMPK |
| 6.872e-05 | -9.59 | HADDAD_B_LYMPHOCYTE_PROGENITOR | MSigDB lists | HADDAD_B_LYMPHOCYTE_PROGENITOR | 269 | 63 | 17758 | 2588 |
PNISR,HLA-F,ARHGEF7,SOD2,ABCG2,PLXNA1,SNN,TRIB2,BARD1,DDR1,TOP2A,ZFYVE16,CDKN2C,RB1,MDM1,PCNA,ENTPD4,DACT1,CD22,RIMS3,FJX1,CD9,CDKN1B,IRF2,PIK3CD,CITED2,RAG1,PTPRE,RASGRP1,SCN3A,TUBA4A,TGIF1,ARAP2,ING1,ELK3,SNTB2,EZR,KIF13A,DNAJB14,CYFIP2,RHOB,DCP2,IRS2,ANKRD10,BTG1,NEIL1,BANK1,ALDH5A1,DCK,P4HA2,SH2D3C,STK38,WFS1,ITPR1,MYLK,LRIG1,CSGALNACT1,TLE1,VSIG10,PKD2,COBL,TOB1,FAM134B |
| 6.966e-05 | -9.57 | cell-matrix adhesion | biological process | GO:0007160 | 122 | 35 | 16441 | 2455 |
BCAM,SORBS1,TAOK2,CD63,ITGA6,ARHGEF7,TESK2,DDR1,EMP2,ITGA2B,EPDR1,LYPD5,ZYX,ITGA3,MUC4,CTNNB1,ITGB8,CTGF,NPNT,LYPD3,ADAM15,CTTN,TIAM1,SNED1,SGCE,RHOA,FBLN5,ILK,DAG1,TSC1,HPSE,COL13A1,ITGA7,ITGAV,TMEM8B |
| 6.984e-05 | -9.57 | GSE3982_DC_VS_TH1_UP | MSigDB lists | GSE3982_DC_VS_TH1_UP | 190 | 48 | 17758 | 2588 |
GAS2L1,PARP12,NFKBIE,LRRFIP2,IL18,MRAS,PLXNA1,MERTK,ARHGEF40,PARM1,GBX2,SNX13,NOV,FAM46A,CAPG,DRAM1,BCL6,TACSTD2,STEAP3,ACOX2,TRAM1,TMBIM1,CRTAP,MCCC2,NAGPA,PDGFC,CTNNAL1,SH3BGRL,CORO2A,PDE5A,BLVRA,NPC2,SESN1,ALCAM,CYB5A,RHEB,SCARB2,LDLRAP1,CTNS,SLC9A6,STAT6,SPINT2,FAM114A1,CLIP4,ARRB1,MAOA,PLXND1,SLC27A3 |
| 6.984e-05 | -9.57 | GSE17721_LPS_VS_CPG_12H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_12H_BMDM_UP | 190 | 48 | 17758 | 2588 |
IL15RA,IL15,LRP4,SERPINB9,PDIA5,ARFGEF1,HMGN3,CHAC2,CACNB4,PSIP1,ITGA2B,HMGXB4,EPS8L2,RB1,CPNE2,WDFY1,TIMP1,PTEN,FRYL,FAM20B,FCHO1,ABCA2,TPST1,CDKN1B,H2AFY,TRIM21,SELK,ECE1,GFI1,SNX10,TSPAN33,DDB2,AK4,KIAA1109,ERBB2IP,IFIT3,CASP4,CD83,NCOA3,UAP1,PVRL2,CSF1,TMEM30A,MPP2,HDAC1,GLCCI1,ISOC1,TMEM173 |
| 7.034e-05 | -9.56 | hyperplasia | COSMIC cancer mutations | hyperplasia | 52 | 19 | 17775 | 2585 |
AKT1,RET,PIK3R1,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,IL6ST,PIK3CA,SMO,MSH2 |
| 7.037e-05 | -9.56 | activation of MAPKK activity | biological process | GO:0000186 | 237 | 58 | 16441 | 2455 |
SPRED1,TAOK2,PSME2,RASA2,PSMD7,CALM3,NRG2,ERBB2,PSMD10,TGFBR1,RASGRP3,PSME1,PDGFB,DUSP5,SPTB,FGF19,CALM2,PDGFA,PSMD1,ADORA1,SHC3,PSMC2,MAP3K9,DAB2IP,ERBB3,NCAM1,MAP3K7,RASGEF1A,F2R,CAMK2G,PSMA5,RASGRP1,FRS3,MAP3K3,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,PSMA4,MAP3K6,EGFR,RASA1,IRS2,PLCG1,FYN,JAK1,FGFR2,PSMD3,FGF18,KIAA1804,MAP3K11,GRIN2D,NRG1,SPTBN5,MAP3K5,JAK3,PSMC1 |
| 7.075e-05 | -9.56 | breast-carcinoma_in_situ-lobular_carcinoma_in_situ | COSMIC cancer mutations | breast-carcinoma_in_situ-lobular_carcinoma_in_situ | 36 | 15 | 17775 | 2585 |
GNAS,CTNNB1,CDH1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR |
| 7.075e-05 | -9.56 | lobular_carcinoma_in_situ | COSMIC cancer mutations | lobular_carcinoma_in_situ | 36 | 15 | 17775 | 2585 |
GNAS,CTNNB1,CDH1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR |
| 7.091e-05 | -9.55 | regulation of catabolic process | biological process | GO:0009894 | 703 | 142 | 16441 | 2455 |
CNOT8,PNPLA2,CUL4B,CUL1,PSME1,CCNB1,SNX9,MAP1LC3B,BARD1,RIC1,DAPK2,PSMD1,ZFP36,PSMC2,PPP1CA,CTTN,TIPARP,PLK1,VPS11,TRIM8,ITCH,PBK,USP18,BNIP3L,EZR,IDH1,RNF19B,TYSND1,CDK1,VCP,ULK2,DNM1L,PLK2,NKD1,PSMC1,LZTS1,RRAGD,PRKAA2,SCOC,GGA1,DNAJB2,SOX9,PRKAA1,ASB9,PSMD7,RB1,TIMP1,DAPK1,SORL1,USP1,USP38,PIKFYVE,MAPK7,MYLIP,PHKG2,PSMA5,SOCS5,QSOX1,USP31,PIP4K2C,TP53INP2,PSMA4,EGFR,PLIN5,INSR,PRKAG2,SH3BP4,FAM83D,AURKA,YOD1,CTSA,TOB1,EGLN1,USP43,DLGAP5,THRA,PSME2,TP53,P2RX7,BCL2L1,PRKACA,APC2,BCAP31,EPM2A,IER3,RAD23A,RALB,DACT1,CDKN1B,TWIST1,DAB2IP,OSBPL7,SIRT1,ERLEC1,TIMP2,AKT1,NRBF2,CDC20,SNX12,IRS2,FYN,PSMD3,PPP1CB,NRG1,CHMP4B,ARNT,TNRC6C,PINK1,SH3D19,DAP,PSMD10,TRIB2,PPP2R3A,RNF128,ADORA1,CTSC,PTEN,GPC3,CST3,UBE2J1,BAX,DRAM1,TRIM21,PLEKHF1,BUB1,WNT10B,PSMB4,GCLC,NUB1,FURIN,PPARA,PRICKLE1,GPLD1,USP6,TIMP3,CENPE,FZD5,UBE2C,NDFIP1,CD81,ESPL1,USP16 |
| 7.106e-05 | -9.55 | acetylglucosaminyltransferase activity | molecular function | GO:0008375 | 47 | 18 | 16491 | 2452 |
PIGC,B3GNT2,LFNG,XYLT1,MGAT4B,HEXB,MGAT5B,POMGNT1,B3GALNT2,EXT2,MGAT1,MGAT4A,ALG13,XYLT2,B4GAT1,POMGNT2,MGAT5,GCNT1 |
| 7.110e-05 | -9.55 | positive regulation of cell cycle | biological process | GO:0045787 | 311 | 72 | 16441 | 2455 |
CCNC,DLGAP5,PSME2,NDRG1,CUL4B,TP53,PSME1,CCNL1,CCNB1,PRKACA,PDGFB,STIL,TP73,NPM2,CCND1,CYP1A1,PSMD1,CTGF,KIF14,PSMC2,PLK4,CDKN1B,DAB2IP,HSPA2,PLK1,PSRC1,AKT1,VPS4B,NUSAP1,AURKB,PSMD3,OVOL1,XRCC3,GEN1,E2F8,PSMC1,NKX3-1,CIT,PSMD7,PSMD10,KIF23,RACGAP1,CALR,RB1,E2F7,IGF1R,PTEN,TRIM21,PIM1,CITED2,PSMA5,HES1,RHOA,ADAM17,PSMB4,WNT10B,RGCC,KIF20B,PSMA4,CDK5R1,EGFR,NUDT16,INSR,FGFR2,CDCA5,FAM83D,NR4A3,AURKA,PKD2,UBE2C,ESPL1,FOXA1 |
| 7.131e-05 | -9.55 | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 185 | 47 | 17758 | 2588 |
TRIM2,ST13,TMEM184B,ATP9A,ZCCHC24,LRP4,MCTP2,APOO,ASAH1,MORF4L2,LACTB2,GNB2,LGALS3BP,TEAD3,LMNA,SCML1,PDGFA,P4HB,RRBP1,ATP13A3,KANK2,MTMR11,KLF9,EPHB4,CTTN,NAGA,TMX1,MYO5A,XKR8,LAMP2,SNTB2,PYGL,GGH,LDB2,MEST,ILK,ATP10D,FUCA1,TIMP3,UEVLD,KCNK1,STAT1,OSMR,ARSB,CHPT1,CSRP2,DENND5B |
| 7.187e-05 | -9.54 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | 101 | 30 | 17758 | 2588 |
CPD,CASP3,CDS2,AGRN,SSH1,HOXB7,TBC1D1,MGAT4B,ARL4C,IL18,TNS1,PLXNA1,SRSF5,CCNB1,GNA11,LGALS3BP,SAC3D1,FAS,IL1R1,CCND1,ETS2,GATA2,MAP3K11,TRIM21,KPNA2,IFIT1,ATP1B3,SGOL1,UBE2C,F2R |
| 7.187e-05 | -9.54 | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | 101 | 30 | 17758 | 2588 |
QSOX1,PGM1,ENO2,ZNF395,S100A4,NDRG1,PLAUR,SOX9,BNIP3L,AK4,LOXL2,PDGFB,DPYSL4,FOS,PGAP1,EGFR,CYB5A,FYN,SRPX,DPYSL2,P4HA2,ITPR1,GYS1,LIMCH1,EGLN3,CITED2,LOXL1,CSRP2,EGLN1,RRAGD |
| 7.190e-05 | -9.54 | positive regulation of cellular component movement | biological process | GO:0051272 | 387 | 86 | 16441 | 2455 |
ACVR1,ATP8A1,RET,COL18A1,GATA3,CD274,CAMK1D,HDAC6,PDGFB,PDGFA,EPCAM,DAPK2,BCL6,TNFRSF18,DAB2IP,TWIST1,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,SEMA3B,DOCK4,BAG4,AKT1,DMTN,SYNE2,DOCK5,IRS2,PTGS2,PLCG1,MYLK,FAM110C,F2RL1,HSPB1,SEMA6B,ANXA3,LGALS3,ARHGEF7,SOX9,SELL,CBLL1,TGFBR1,ETS1,FBLN1,SRPX2,ICAM1,NRP2,ITGA2B,HDAC9,CALR,BMP2,RAC2,CXCL16,PDCD10,ITGA3,IGF1R,CYR61,MEGF8,NTN1,EPB41L5,SUN2,RHOA,ADAM17,RAPGEF2,ANO6,PIK3R1,FURIN,KIF20B,EPHA1,ILK,BCAR1,EGFR,GPLD1,ONECUT1,SWAP70,INSR,SEMA4D,PLPP3,CSF1,FGF18,ITGAV,GPER1,CFAP20,SEMA3A,DRD1 |
| 7.207e-05 | -9.54 | MODULE_243 | MSigDB lists | MODULE_243 | 78 | 25 | 17758 | 2588 |
FAM171B,TM2D2,JRKL,ACBD3,PDCL,PSMD10,SLC11A2,NDUFA4,FAM198B,RAD17,BCL2L1,PJA2,LBR,TSPAN7,M6PR,PDGFA,AMZ2,PCNA,TSPAN6,WDR19,APPL2,DCUN1D1,EGFL7,RTN3,TOB1 |
| 7.207e-05 | -9.54 | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | MSigDB lists | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | 78 | 25 | 17758 | 2588 |
MYL9,BIN1,LTBP1,FBLN5,ERMP1,EPAS1,NDRG1,CD82,SOX9,SYBU,LMCD1,KDELR3,ICAM1,MAP1B,CD83,SCNN1A,MLPH,AOX1,SORL1,ACTA2,TSPAN13,EFNA1,LTBP2,EPB41L4B,IFIH1 |
| 7.212e-05 | -9.54 | haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_neoplasm | 11621 | 1775 | 17775 | 2585 |
HECA,IBTK,GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,TRAPPC8,BAIAP3,SNX9,FAM46C,SPSB1,CMTM6,CARD10,LTBP3,GRM5,LYPD5,CDKN2C,NPM2,MUC4,UBE2T,PAQR5,ATP13A3,DNM2,CRY2,RNF26,WBP4,TIAM1,IL10RB,CPE,TIPARP,MGAT5,DNAAF3,CCDC74A,NEK4,FBXL16,CDA,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,LCP1,ENPP1,BOLA3,PLCG1,MPRIP,ATP7B,CELF5,TRAF3IP1,FAM114A1,TMOD2,RNASEL,ITPKA,STARD13,ANXA11,ZNF720,SCN5A,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,ATG4A,MARCH8,FLII,RAC2,FRY,PAIP2B,MEGF8,FLRT3,RANBP1,FBXL14,PCYOX1,MAP3K9,SLAIN2,CADPS2,USP38,ALPK1,CNGA1,MAPK7,ZMYM1,MOXD1,MYLIP,ULBP2,DGKG,KANK3,NUP85,PHKG2,MCCC2,HPS3,SHARPIN,FHL2,KIF20B,NPHP3,GOLT1A,DPYSL4,SFXN5,GNA11,PLIN5,IL1R1,CACHD1,SLC4A4,ETS2,APMAP,RAET1L,S100A5,DGAT2,CLMN,OSCP1,CBX5,TMEM173,ADAMTS16,DMPK,DOCK9,WDR63,LFNG,PTTG1,RHBDL3,GRK6,MGST2,FAM91A1,MOCS1,KIAA1147,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,ZNF365,MYT1,SNX10,TMCC2,MX1,SNX8,COL6A2,RIPK2,APOBEC3D,PFKFB2,AGPS,PTPN9,SEPT6,DNAJB14,TANC1,ZNF618,TRIM7,EBF2,NFIX,SPIN3,PDLIM3,SHROOM3,CDK19,WFS1,AXL,PNPLA6,FAM149A,ISOC1,MAPK12,CTHRC1,MZT1,HSP90B1,MPZL1,FAM189A2,GCAT,ESRP1,TRAF2,HABP4,CCM2,SDC4,FLOT1,CTSZ,ZNF219,PLPPR4,SLC25A43,NFAT5,FUT2,ITGB8,KNDC1,MGAT4A,TMEM62,TUBGCP6,FAM20B,RAG1,CASD1,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,CXorf57,UBE2A,PGBD1,RAB3IP,C4orf27,CNTNAP1,RGPD5,RPL12,PROM1,HCP5,PLOD2,RAB11FIP2,SYT7,SLC35B3,FAM3C,PPM1H,ITGAV,OSR1,CMPK2,PHC1,TLL2,TMEM131,CCNI,ILDR1,TNK1,BCAM,KIAA1462,EPAS1,LMCD1,PHOSPHO1,DNAJB11,TEX2,F11R,GALM,MGAT5B,ITPR2,SPTB,SLC9A3R2,FANCI,TFAP2E,PLS3,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,NPNT,IL6ST,PSMC2,PAPSS1,SLC44A1,ABCA2,NTN4,SMAGP,PLK1,KRT80,THRB,PTPN18,MARK1,CELSR2,STAU2,NFE2L1,CR2,CCBL2,NKAIN1,EAF2,SESN1,TRUB1,DZIP1L,KDM4D,TRIM9,TNS4,HS6ST1,TRAM2,KLF12,HOXA9,ARRDC1,KLF11,KPNA2,MYL12B,TC2N,HS6ST3,RRAGD,PARP12,RUNX2,USH1C,HJURP,DNAJB2,FXYD3,RASA2,SORBS3,ADCK5,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,SELK,PIM1,FAR2,WNT3A,NTN1,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,BCL2L13,PRX,NMT2,C18orf8,FA2H,COL13A1,KBTBD2,PHLPP2,P4HA3,NLRC5,ZDHHC7,ZDBF2,PLD1,AKIP1,SEMA3A,CDAN1,USP43,RAD21,HOXB7,CTDSPL,TMX4,TP53,RHPN2,P2RX7,BAHD1,EMP2,PRR7,STIL,SYTL2,PDGFA,TTC21B,WDR44,TACC2,PPME1,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,ZNF628,IDE,PTPRJ,ABHD12,RBL1,STK38,MAOA,EFNA5,IRF7,SYT13,ARHGAP4,ST3GAL1,FAM134B,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CDH22,CPEB4,CTSB,GNAL,MCTP2,HAL,CDCA8,ERI2,GTF3A,HMGN3,LBR,IL22RA1,PARM1,VPS26A,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,CD109,FOXP2,ALPP,CDK16,GTF2F2,FAM63A,IL17RA,TRIM21,SGK1,CPLX1,ALDH7A1,SYK,LRRC24,DUSP1,P2RX4,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,BCL10,USP6,DDX23,CNOT2,DDAH1,SMTNL2,NEIL3,NIPSNAP3A,E2F1,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,VANGL1,CUL1,PDGFRL,PSME1,CAMK1D,NANS,VASH1,OAT,PJA2,PICK1,SLC9A7,PAK6,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,POLL,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,METAP2,SPATA18,ACVR1C,CDYL,BNIP3L,KIF13A,LDB2,POR,RAB2B,PRIM1,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,SERPINI1,SPRY4,WBSCR27,F2RL1,SLC31A2,CCDC97,FGD1,SEMA6B,RECQL,MRC2,TBC1D1,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,SH3RF2,MESDC2,CALR,DOPEY2,RALGPS2,LYPD3,ZNRF2,RPL39,AIM1,MSH2,DAPK1,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,DLX4,KCTD3,SYTL3,TRAK2,PIGC,GFPT1,SPATA20,GCC2,PRODH,KCNJ12,KLK5,CEP89,ADCK3,DCHS1,PYGL,WHSC1,NPC2,ATP8B3,ANTXR1,NFIB,PDE11A,NT5C2,PLEKHH2,TJP3,FAAH,ZDHHC20,C1orf21,MATN2,PIAS2,FAM83D,MPP2,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,ZBTB34,PER3,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,CAPN12,CCDC110,NDRG1,CERCAM,ATP2C2,FTH1,BLCAP,BCL2L1,TMEM170B,TMEM19,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPS8L2,APOBEC3B,NOV,CCNA2,ACAP2,TRANK1,RALB,BRI3,EPHB4,PDE4D,OSBPL7,SULT2B1,FLOT2,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,CLSTN1,UTRN,KIF1C,PKMYT1,B3GALNT2,CBL,ITPR3,ASB13,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,POPDC3,ACAD10,CCDC149,TSPAN18,ZNF704,SLC27A3,COBL,CBX7,MAMDC2,PRKAR1A,PLSCR4,DEPDC1,HAPLN3,CENPI,EPS8,NES,HERC5,PBX3,PLD2,FBXO6,DNAH3,HLA-A,WWP2,SLC25A36,CKAP5,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,ERBB3,CITED2,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,UBAC1,YES1,GRTP1,KIF11,CDK5RAP1,CRTC2,TIMP3,ACADSB,DGCR2,SEC14L4,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR62,WDR91,ESPL1,MELK,UGT8,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,COMMD5,TRIM68,ECI1,HTR1D,ADPRHL1,RAB15,SIPA1L2,CDKL5,CASC4,ARHGEF37,SIVA1,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,STK35,CYP1B1,NLRP4,CENPA,ASXL1,ACBD3,USP18,RGAG1,ARHGDIB,MAN2A2,GPRC5B,KCNK1,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PCSK5,CD99,LASP1,PPP1R2,PPP1R12A,SERPINE2,BVES,PYROXD2,ABCG2,PM20D2,FAM81A,DUSP5,QSOX2,TYW3,B3GALNT1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,SNED1,MDFI,SNX7,TPGS2,ELK3,PODXL2,PDE5A,KIAA1109,PRRC1,HEATR5A,PDIK1L,C3orf58,MFSD7,RANBP9,STEAP1,INSR,TMEM30A,SPAG7,DCUN1D1,SH3BP4,RAB31,DONSON,CTSA,SHROOM2,JAK3,COL16A1,AFAP1,DRD1,CCNE2,LMO7,NCKAP5,LZTFL1,PAX6,PDIA5,COL18A1,IL27RA,KCTD9,SAP130,ZNF687,CYP4F11,KIF14,REEP1,ZBTB49,EPB41L4B,ECE1,NFKB2,UPF3A,EBAG9,SEPHS1,SOAT1,PTPRU,MRPS35,GLO1,TMTC2,CDC25C,FANCE,PDHX,ARHGAP35,HSF4,ALDH5A1,STAT6,PTBP3,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,ARHGEF7,SHPRH,SH3D19,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,SYDE2,TMEM63A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,ZDHHC13,ACTA2,H2AFY,ARVCF,KANK2,CLIP2,SLC35A1,MYO5A,PGM1,DCAF6,SYBU,TTC7A,FAM73B,LEPR,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,FIBCD1,SPINT2,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,ABCG1,CD33,NGEF,ACACB,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,MMADHC,CACNA2D2,SMARCAL1,DHX8,NRG2,IL18,LGI3,SYTL4,CNTROB,CA8,BARD1,KIF26A,DAPK2,TP73,ZYX,WEE1,TGFBR3,RGS12,AP1M2,PQLC2,ARHGAP42,KIAA1107,DNAH6,CYP2S1,CABP1,SLC46A1,RDH14,ALDH1A3,FUT1,TUBG1,PIK3CD,ODF2L,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,RNF11,MTRF1L,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,WDR11,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,RELL1,PDPR,GAB1,E2F8,NFKBIE,FAM169A,ALDH6A1,TMTC3,CYP2J2,SLC36A4,MERTK,RAVER2,GNS,DNPEP,WDFY1,FAM189A1,CD22,NEK2,STT3B,NCAM1,EPHX1,NAGPA,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SPTLC2,CYB5A,RHOB,STK17A,DHX32,PTPRF,SCARB2,NAAA,NCOA3,MTFMT,HTT,TEX30,ITPR1,DYSF,AURKA,OSMR,FBXO27,NDE1,DRP2,SERPINB1,TRPC3,ZNF502,RPS6KA3,XDH,ARHGAP11A,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,FAM131C,ACTR8,WDTC1,RGS20,ETNK1,TESK2,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,UHRF1BP1L,SCNN1A,RNF220,SP100,DACT1,RTKN2,TMEM9,SCN3A,RNF169,ENPP4,SSH3,PSRC1,LGALS8,FZD4,SYNE2,CDCA2,STX10,TTC12,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,TAOK2,TNRC6C,PLEKHJ1,RASSF7,PDIA3,GMCL1,ANO9,PKN1,GSTP1,ETS1,KCNC4,TIPRL,NEO1,PDIA4,CAPN2,DTX3L,CXCL16,ANK1,ADD3,IRAK1,SLC27A6,ANKS1B,FAM160A2,ARSG,KCNK5,CALD1,ALG13,FDXR,PLEKHF1,ECI2,MAPK11,ZNF230,WWP1,NPTXR,ITM2C,TMX1,CRTAP,AMOTL2,LCA5,CTNNAL1,FMN1,RAPGEF2,EIF5A2,GRIN1,PLEKHA7,MYEOV,EMP3,BLVRA,SKA1,CRISPLD2,ABLIM2,TXK,PITX2,GALNT3,KIAA0141,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,CENPE,SHOX2,DCBLD1,CYBRD1,MYL9,UNKL,TRIM2,AGRN,FAM199X,PPM1J,EPHA4,CUL4B,SUDS3,FHDC1,MCCC1,TP53I11,CDIPT,HDAC6,CNTRL,SHC3,MKRN3,ELF5,RGS5,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,MCTP1,HN1L,EZR,C12orf65,ERP44,KLK6,ESYT1,PRKRA,ANLN,FAM212B,IDH1,CLCN2,ZBTB7B,RHEB,VCP,PLEKHB1,OPTN,DPYSL3,MFAP3L,TBC1D17,WIPI1,MAP2,P4HA2,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,POMT1,GLCCI1,MAFF,PRKAA2,UBASH3B,ZCCHC24,HLA-F,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,RB1,VASP,DAZAP1,IGF1R,GATA2,MDFIC,TMEM8A,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,WDR72,TESK1,PCBP3,SPATA13,TCF7,EIF2AK1,IFIT3,UNC45B,G2E3,SMN1,DHDH,MAPKAPK2,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,ATP1B3,IFI6,NIPA1,NF2,UGP2,FOXM1,XYLT1,DGKA,CCDC68,ZNF28,ERBB2,SLC7A2,CCNL1,LPIN3,CYP26A1,PER2,RAD23A,CDK14,SRPX,EFR3A,PLCG2,GYS1,MINPP1,SCN2A,FAR1,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,TCEB2,FIGNL1,COQ10B,CDC20,MYL12A,DNAJC10,DUOX1,ATP1A1,RTN4RL1,C19orf66,PTK7,PSMD3,ADAMTS14,ANXA9,RPL22,LTA4H,AIFM3,ZNF701,NDST3,ZC3HC1,MAN2B2,COL9A3,GOLIM4,TRAPPC10,MACC1,RUSC2,DAP,GNE,GABRG2,SELL,NKRF,SLC9A2,PPP2R3A,SIRPA,CCDC92,CEP97,SLC35B4,ABCD1,BUB1,KLF9,SLC45A3,CAMK2G,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,PPARA,TRIM35,CAPNS1,AKAP3,FXR2,BCAR1,MAPK8IP1,PRDX4,TMEM50B,BANK1,CDKN2AIPNL,SERPINA1,FAT4,TWSG1,ZMYND19,ZNF214,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,PKD2,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,ACVR1,TMEM41B,ATP8A1,KLC2,TAP1,PPFIBP2,GATA3,PLXNA1,SLC20A1,CENPN,NCS1,SESN3,ELMO2,ZFP36,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,PIF1,GALNT7,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ULK2,ARHGEF26,SGPP1,AHRR,SFXN1,FAM177A1,SLC25A4,AREG,PLK2,PTER,TBX1,GNPTAB,NKD1,DHTKD1,TANC2,UNC5B,RTN3,LZTS1,DLAT,DDX58,MRPL44,INPPL1,CDK17,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,NOTCH2,SLC1A3,BMP2K,PRRG4,MECOM,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,BDH1,OPN3,CTPS1,SORL1,CD70,PIKFYVE,RIMS2,TSPAN33,EEF1D,FAM69A,IGSF3,DNAI1,EPB41L5,PMPCB,QSOX1,B3GNT7,MFI2,KIAA1841,MMD,ZNF84,TBC1D8B,B9D2,AMER1,PTPRH,ANO6,PIP4K2C,VEZT,PKM,KDM3A,FBXO10,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,NAB2,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,EFNA1,MAP3K5,NRBP1,IRF1,PKD1L2,ELK4,FRMPD3,PLA2G4A,ARMCX3,TRIP10,NLRX1,BROX,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,AIFM2,MNS1,TMPRSS4,SLC25A35,APLP2,ZNF75D,FAM46A,CDKN1B,IFIT1,LGMN,PHKA2,NR2C1,TMBIM1,GPX4,TBC1D10B,MYO5B,SLC5A11,CDKN2AIP,SEC23A,TMEM43,CAPN6,TEP1,COX11,PRKCQ,AKR1E2,SP4,PRDM11,CMTM7,NIN,OSBPL2,EPHA10,FYN,JAK1,KIAA1804,STAT1,NRG1,MLKL,ZC3H12B,B4GALT3,NR3C2,ATMIN,DENND5B,OTUD5,MRPS9,WASF3,ARHGEF3,SLC16A14,ATP9A,ARL4C,CCNJL,GPR180,APOBEC3H,SEPP1,PNPLA5,SIX4,TMCC3,FAM111A,PHF7,PTEN,MGAT1,CENPJ,SGK3,PRC1,ATP8B1,SLC44A2,TAGLN2,MAP3K7,CNOT6L,GFI1,SPRY2,NCOA2,OSGIN1,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,ERMAP,PARP4,C1GALT1C1,LRRC1,GPLD1,RGS9,NUCB1,MAMDC4,RCBTB2,CSTF2,CCDC69,SERPINB5,SLC25A38,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,LTBP1,CASP3,ST13,CPT2,CAMKK1,UBE2Z,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,LRRC6,GRHL1,DPYSL2,PHTF1,DLG1,CAPG,POF1B,ANKRD12,SUN3,RAB20,RP2,ARNT2,MYH14,TECR,SLC39A10,PTPRE,RASGRP1,OLFML2A,ATL1,TDP1,SYNE3,RNF165,ROR1,MRPS18A,PTGFRN,MRPS36,ADRBK2,STK17B,TCN2,SEC14L2,EDNRA,CXXC4,LRRC42,NEIL1,FASTKD1,IARS2,TRIM45,CCDC74B,ADIPOR1,APBA2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,ELOVL7,SAMD9,PHLPP1,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FXYD5,FNIP1,ZNF692,KNTC1,RFX5,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,HP1BP3,PARD3B,OXR1,GYLTL1B,BTN3A2,RNF113A,EGFR,GNAS,BCAR3,XKRX,TSC1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,PITPNA,KIF12,SLC25A24,ZSWIM5,FAM92A1,IL15,SLC2A8,PSME2,ABCG4,GMPR,TDRKH,ZMYND10,MICALL2,LRRC45,SLC25A48,KCTD15,SETDB2,KHNYN,FRYL,SMO,RPN2,STEAP3,PDIA6,LOXL1,SCYL3,FRS3,MAP3K3,GCA,ZNF525,KREMEN2,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,CANT1,VSIG10,PLXND1,AKNA,SGOL1,REEP4,PPP2R2D,LIFR,CBX4,CCDC24,ANXA3,CDS2,SORT1,POC1B,JKAMP,LRP4,FAM134A,MIER3,NOTUM,FAM167A,SAC3D1,IL17RB,IRF2BPL,SNX13,MDM1,ADORA1,MLPH,GALNS,KIAA0319,BRD7,TRIM3,CKS1B,HSPA13,IQGAP3,SYPL1,SUN2,DEPDC4,GCLC,PHLDB3,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MPV17L2,MAP1B,KLHL2,HLA-B,C2orf70,PRCP,UBE2D2,OTUB2,GLB1,HOXB13,ATP6V1C1,GEM,L1CAM |
| 7.254e-05 | -9.53 | HUANG_FOXA2_TARGETS_DN | MSigDB lists | HUANG_FOXA2_TARGETS_DN | 36 | 15 | 17758 | 2588 |
GAS2L1,SPP1,SRPX,IGFBP6,COL13A1,S100A4,PLAUR,CTSB,COL6A1,CRIP2,CDH3,STEAP3,LOXL2,ACOX2,LEPR |
| 7.276e-05 | -9.53 | regulation of immune response | biological process | GO:0050776 | 949 | 184 | 16441 | 2455 |
LAMP1,UNC93B1,TRIM5,XIAP,TAP1,CUL1,NRG2,GATA3,PSME1,ITPR2,CACNB4,PDGFB,SPTB,CALM2,PSMD1,RPS6KA2,SHC3,ELMO2,IL6ST,PSMC2,PIK3CA,DUSP10,PIK3CD,SCARA3,SMAGP,RASGRP1,CD55,TNIP1,ITCH,USP18,CASP9,CR2,AGO4,ABR,PLCG1,GPRC5B,LIMK1,NOD2,F2RL1,PSMC1,GAB1,PPP2R5D,DDX58,LGALS3,THEMIS2,HLA-E,RASA2,HLA-F,PSMD7,CALM3,TEC,NCKAP1,PHLPP1,DUSP5,RAC2,VASP,PIK3AP1,PAK2,HLA-C,C10orf54,NCAM1,MAPK7,PSMA5,SOCS5,KLK5,MAPKAPK3,MICB,CALM1,WHSC1,ELK1,CYFIP2,PSMA4,EGFR,RASA1,MAPKAPK2,PVRL2,PELI2,PHLPP2,ITPR1,NFKBIA,NLRC5,KLK7,ARPC2,IFIH1,JAK3,RPS6KA3,TMEM173,IRF1,SPRED1,NLRX1,IL15,INPP5D,RPS6KA1,PSME2,ERBB2,P2RX7,IL27RA,RASGRP3,PRKACA,CD46,PDGFA,CDH1,PLCG2,BCL6,CDKN1B,DAB2IP,PDE4D,RASGEF1A,LGMN,NFKB2,FRS3,SIRT1,RIPK2,AKT1,PRKCQ,ITPR3,DUSP4,CD40,SOCS3,IRS2,FYN,PTPRJ,JAK1,STAT6,PSMD3,STAT1,NRG1,IRF7,SPTBN5,TNRC6C,HSP90B1,TAB3,TRAF2,CTSB,SERPINB9,BTN3A1,PSMD10,SELL,PLD2,PKN1,FGF19,ICAM1,HLA-A,IRAK1,PTEN,BAX,MAPK11,ERBB3,MAP3K7,CNPY3,SYK,CAMK2G,MSH6,PARP9,RASGRF1,PLSCR1,PSMB4,RAPGEF2,NR4A1,PIK3R1,GRIN1,RGCC,VAMP3,YES1,FOS,BCAR1,GPLD1,TXK,BCL10,CTSL,HLA-B,CD8A,FGFR2,FGF18,NMI,NR4A3,UBE2D2,ERAP1,PPP2R3C,GRIN2D,FZD5,CD81,NDFIP1,CD33 |
| 7.306e-05 | -9.52 | heparan sulfate proteoglycan metabolic process | biological process | GO:0030201 | 28 | 13 | 16441 | 2455 |
B3GALT6,HS6ST1,HPSE,XYLT2,XYLT1,CSGALNACT1,HS3ST3B1,DSE,EXT2,NDST3,GLCE,SULF2,HS6ST3 |
| 7.313e-05 | -9.52 | SIGNAL_TRANSDUCTION | MSigDB lists | SIGNAL_TRANSDUCTION | 1606 | 287 | 17758 | 2588 |
ACVR1,TXN,IL15RA,GRIK2,RET,NRG2,SLC20A1,CARD10,PICK1,GRM5,CALM2,TP73,DAPK2,ZYX,RGS12,TGFBR3,RGS3,IL31RA,TACSTD2,TFG,IL10RB,CASP9,PRKAR2B,ABR,PGF,CARHSP1,DNM1L,LIMK1,PLK2,SH2D3C,MAP3K11,NOD2,MAPK13,ITPKA,ARF6,TRAF5,F2RL1,GAB1,FGD1,CDKN1C,PRKAA1,STRN4,NOTCH2,GPSM2,MERTK,RAC2,RANBP1,DAPK1,OPN3,MAP3K9,PRKG1,CD70,OSTF1,PIKFYVE,MAPK7,NUP85,EEF1D,SOCS5,MAPKAPK3,STAT4,CALM1,CALCRL,EPHA1,GNA11,RHOB,PDE11A,FAS,STK17A,PTPRF,GABRD,FNTA,ARAP1,MPP2,APPL2,FGD6,OSMR,MAP3K5,RPS6KA3,DMPK,SPRED1,REPS2,S100A11,TRIP10,RALBP1,INPP5D,IQGAP1,RPS6KA1,RGS20,IL13RA1,CD274,BCL2L1,GRK6,MGST2,APC2,FLT3,TNFSF9,GNB2,ZFYVE9,CDS1,CCNA2,RALB,TAX1BP3,MED30,MX1,CDKN2AIP,RIPK2,RAD17,ITPR3,CBL,ALCAM,IRS2,FYN,CORO1C,AXL,STAT1,INPP4B,KIAA1804,RGS14,NR3C2,PRKAR1A,MAPK12,TAOK2,MPZL1,TRAF2,EPS8,CCM2,BIK,PDIA3,PLD2,PKN1,LGALS3BP,CTNNBIP1,DIRAS3,IRAK1,PTEN,BAX,SLC44A2,MAPK11,ERBB3,MAP3K7,CITED2,S100A6,FARP2,MPP1,PIK3R1,CNTNAP1,RGS9,ACVRL1,NR4A3,RYK,CD81,CASP3,BCAM,SIGIRR,EPAS1,AGRN,EPHA4,ITPR2,HTR1D,ARHGEF10L,RPS6KA2,SHC3,DPYSL2,TSPAN6,IL6ST,DUSP10,RGS5,TNFRSF18,RASGRP1,SOD1,MARK1,CXXC5,KCNIP3,ARFRP1,ARHGDIB,ROR1,STK17B,ADRBK2,VCP,RHEB,DPYSL3,EDNRA,OPTN,PLCH1,MADD,ADIPOR1,NRGN,RAP1GAP,PRKAA2,ARAP3,CALM3,IL18R1,IGF1R,LRRN2,PAK2,MDFIC,PLCB2,MDFI,DPYSL5,ELK3,RGMB,CORO2A,CDK5R1,EGFR,BCAR3,GNAS,MAPKAPK2,TSC1,INSR,PLD1,LTBP2,COL16A1,IFI6,DRD1,SORBS1,NF2,IL15,DGKA,TP53,ERBB2,P2RX7,IL27RA,MRAS,EXT2,PDGFA,ARTN,F2R,FRS3,MAP3K3,AKT1,PTPRU,PTGER4,ERBB2IP,DUSP4,CD40,MAP3K6,SOCS3,DUOX1,PTPRJ,STK38,STAT6,PTK7,SECTM1,TLE1,CANT1,ARHGAP4,AIFM3,LIFR,ABCA1,ANXA3,PINK1,ARHGEF11,ARHGEF7,GNAL,SERPINB9,GABRG2,TGFBR1,GDF15,CRABP2,XPR1,TOP2A,CARD8,ADORA1,ADRBK1,ZDHHC13,P2RX4,RHOA,NR3C1,NR4A1,AMFR,LITAF,BCAR1,LEPR,MAPK8IP1,BCL10,PRDX4,CD83,DDAH1,CASP7,SCG2,FGF18,NMI,ARRB1,GEM,NDFIP1,ZBTB33,CD33 |
| 7.328e-05 | -9.52 | growth factor binding | molecular function | GO:0019838 | 118 | 34 | 16491 | 2452 |
LTBP1,SCN5A,SORT1,ACVR1,IGFBP6,ERBB2,TGFBR1,PDGFB,LTBP3,SRPX2,NRP2,CD109,PDGFA,NOV,TGFBR3,CTGF,IGF1R,CYR61,IL6ST,VASN,COL6A1,IGFBP2,ERBB3,S100A13,SEC61B,ACVR1C,FURIN,INSR,FGFR2,ACVRL1,OSMR,LTBP2,ITGAV,LIFR |
| 7.339e-05 | -9.52 | MODULE_212 | MSigDB lists | MODULE_212 | 324 | 73 | 17758 | 2588 |
NQO1,UGP2,HEXB,MGST2,OAT,CYP26A1,PCNA,CYP1A1,P4HB,METTL7A,PLCG2,GOT1,RAB20,ACOX2,MANF,ARL4D,PLK1,SOAT1,SOD1,LAP3,SAT1,ACO1,GLO1,TNS1,F12,MCFD2,IDH1,CDK1,DPYSL3,ENPP1,NRG1,CHPT1,PPP2R5D,PRSS8,CYP2J2,BLVRB,HAL,FLOT1,KIF23,PDIA3,DUSP5,PDIA4,TOP2A,CA2,IRAK1,CTSC,TUBGCP6,PCYOX1,DAPK1,TMBIM6,ALDH7A1,PIM1,MCCC2,FAH,ABCC1,FADS2,IFITM3,MPP1,FURIN,PYGL,STRADB,GGH,CYB5A,PRDX4,FUCA1,ACADSB,RND3,NAT1,GLB1,MDH1,ACADM,MELK,XDH |
| 7.395e-05 | -9.51 | RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)) | protein interactions | 5879 | 190 | 51 | 16036 | 2547 |
GRN,UNKL,CASP3,USH1C,CIT,RALBP1,IQGAP1,ARHGEF7,XIAP,TEC,NCKAP1,LTBP3,KTN1,SH3RF2,TOP2A,PAK6,DAZAP1,NOXA1,SH3BP1,MCF2L,OCRL,PAK2,PRKCI,TNFRSF12A,IQGAP3,TIAM1,IL1RAP,DVL2,METAP2,TUBA4A,RASGRF1,AKT1,PIK3R1,ARHGDIB,PKM,ICMT,RHOB,CFAP36,ARHGAP35,USP6,PIAS3,CASP7,PPP2R4,STAT1,MAP3K11,KPNA2,PLD1,DEF6,ANXA11,DMPK,ARHGEF4 |
| 7.450e-05 | -9.50 | cell-cell junction | cellular component | GO:0005911 | 377 | 83 | 17570 | 2579 |
ILDR1,SORBS1,KIAA1462,GRHL2,NDRG1,IQGAP1,PKP2,P2RX7,F11R,MPP5,MICALL2,CCND1,EPCAM,ZYX,NOV,CDH1,CTNNB1,DLG1,AKR1B1,CLDN4,CDH3,POF1B,EPB41L4B,SCN2A,TLN2,DLG3,TIAM1,FLOT2,SMAGP,KRT80,CAMSAP3,AKT1,PTPRU,FZD4,ATP1B1,DAG1,PLCG1,PTPRJ,ATP1A1,SHROOM3,PTK7,MYLK,CTNND1,DDX58,SCN5A,PACSIN2,FRMD4A,BVES,FRMD6,CALB2,FLOT1,TGFBR1,TEC,VASP,ADD3,TBCD,PRKCI,PANX2,PIKFYVE,IQGAP3,PVRL4,AMOTL2,CASK,RHOA,PCDH1,ADAM17,CRB3,PARD3B,RAPGEF2,PIK3R1,PLEKHA7,SCRIB,ILK,STEAP1,STX3,TJP3,COL13A1,PVRL2,RAP2C,PKD2,FZD5,SHROOM2,OCLN |
| 7.494e-05 | -9.50 | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | 170 | 44 | 17758 | 2588 |
GCLM,DYRK3,TXN,GNPDA1,OSGIN2,IL18,CD274,SNX9,DUSP5,SCML1,IER3,E2F7,SGK1,SELK,PIM1,EGLN3,SPRY2,RPGR,OSGIN1,WBP5,DUSP1,CKS2,HES1,B3GNT2,RIPK2,NR4A1,COQ10B,RAPGEF2,PLAUR,PTGER4,PIM3,SAV1,STX3,SOCS3,SLCO4A1,PTGS2,ETS2,CSF1,NR4A2,NFKBIZ,GLA,PLD1,GEM,ZC3HC1 |
| 7.495e-05 | -9.50 | regulation of biological process | biological process | GO:0050789 | 10636 | 1671 | 16441 | 2455 |
HECA,IBTK,GRIK2,PNPLA2,HEXB,RET,BAIAP3,SNX9,SPSB1,CARD10,LTBP3,GRM5,ZNF275,NPM2,CDKN2C,PHYHIP,DNM2,CLDN4,CRY2,PPP1CA,TMEM37,TIAM1,IL10RB,TIPARP,CPE,ANKRD9,NEK4,DSTN,UXT,CDA,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,LCP1,ABR,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,TRAF3IP1,NOD2,HDAC1,TMOD2,RNASEL,ITPKA,HSPB1,STARD13,ZNF720,SCN5A,GGA1,SEC61G,ITGA6,RAB23,GPSM2,FAM21C,HPCAL4,MARCH8,TFAP4,FLII,RAC2,ZCCHC17,PAIP2B,MEGF8,RIMS3,FLRT3,FBXO7,RANBP1,MAP3K9,SLAIN2,USP38,USP1,ALPK1,MYDGF,CNGA1,MAPK7,DGKG,MYLIP,NUP85,PHKG2,PPP6R1,PAQR7,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,GNA11,PSMA4,PLIN5,IL1R1,FNTA,ETS2,DGAT2,CLMN,OSCP1,STK39,GDF11,CFAP20,CBX5,NUP58,TMEM173,RUSC1,ADAMTS16,DOCK9,DMPK,NQO1,LFNG,INPP5D,CD82,PTTG1,MAPK4,GRK6,MGST2,MVB12B,ST5,CDH1,SH3BP1,TAX1BP3,DLG3,RASGEF1A,MYT1,ETV4,MX1,SEC61B,RIPK2,APOBEC3D,PFKFB2,SAT1,VPS4B,HTATIP2,SYP,GTF2A2,SNX12,ZNF618,EBF2,GIGYF1,NFIX,CCNB3,CDK19,SHROOM3,CORO1C,WFS1,AXL,MAPK12,CTHRC1,TCAF1,HSP90B1,MPZL1,CKAP2,TRAF2,ESRP1,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,CTSZ,PLPPR4,ZNF219,HDGFRP2,IFT27,NFAT5,BEX2,SGPL1,CTNNBIP1,DIRAS3,ZFX,PDCD10,ITGB8,IGSF9,KNDC1,GPC3,FAM20B,CST3,TUBGCP6,BAX,IGFBP2,RAG1,MED22,PARP9,PLSCR1,TACC1,PIK3R1,NUB1,UBE2A,PGBD1,RAB3IP,PIM3,CNTNAP1,LDLRAP1,PROM1,SYT7,SLC35B3,DBI,NR4A3,SSNA1,ITGAV,OSR1,CD81,SRSF9,TMEM131,CCNI,ILDR1,BCAM,TNK1,EPAS1,CNOT8,ARFGEF1,LMCD1,PHOSPHO1,NDRG2,DNAJB11,F11R,TEX2,NENF,ITPR2,SPTB,FANCI,TFAP2E,SUSD2,BTG3,RPS6KA2,NUP210,CTNNB1,RABEP2,NPNT,P4HB,IL6ST,ARL1,PSMC2,MITF,PASK,ABCA2,NTN4,SCARA3,SMAGP,PLK1,THRB,KCNIP3,MARK1,CELSR2,CBX6,NFE2L1,CR2,ARFRP1,NKAIN1,EAF2,SESN1,KDM4D,TRIM9,PLEKHG6,KCNMB4,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,KPNA2,TC2N,MYL12B,RRAGD,PRSS8,RUNX2,LMTK3,HJURP,LGALS3,DNAJB2,FXYD3,RASA2,PDCL,PSMD7,SORBS3,RAB6A,HES2,NCKAP1,FBLN1,ANO1,TNS3,TIMP1,RINL,KIF13B,TBCD,SLC30A6,SELK,PIM1,NTN1,WNT3A,DPYSL5,USP31,RGMB,ZNF320,STRADB,SCRIB,ZSCAN12,PDK3,BCL2L13,NMT2,CDK5R1,FOXD2,RASGRP2,FA2H,PHLPP2,NLRC5,FAM213A,PLD1,SEMA3A,CDAN1,CCNB2,USP43,RAD21,HOXB7,CTDSPL,TMX4,TP53,P2RX7,RHPN2,BAHD1,STIL,EMP2,BCAP31,SYTL2,IER3,TTC21B,PDGFA,KMT5C,TACC2,LMO4,PPME1,BCL6,PLK4,CDH3,VAT1,ESPN,NOTCH3,OAS3,TMEM64,LMAN1,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,CCSAP,SERTAD3,PTGER4,ACO1,C3orf33,DAG1,PTGS2,ZNF628,PTPRJ,IDE,RBL1,MMP17,STK38,CHMP4B,XRCC3,EFNA5,IRF7,SYT13,ARHGAP4,FAM134B,ARFGEF3,CTDSP1,BIN1,ZMAT1,PINK1,CPEB4,TAB3,CTSB,GNAL,MCTP2,CDCA8,ERCC6L,GTF3A,GDF15,HMGN3,AIP,IL22RA1,PARM1,DNAJB9,SH2D4A,FZD6,NRP2,M6PR,ZDHHC21,CD109,FOXP2,CDK16,GTF2F2,UBE2J1,TFAP2A,SGK1,IL17RA,TRIM21,CPLX1,TSPAN13,SYK,FAM134C,DUSP1,WBP5,NFE2L3,P2RX4,HES1,FBLN5,RHOA,HMGN5,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,COL7A1,BBS2,TXNDC11,DGKE,USP6,BCL10,CNOT2,DDAH1,SCG2,FGF18,E2F1,ICOSLG,PTGES,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,LAMP1,TXN,SSH1,LGR4,HSPG2,TSC22D3,CUL1,PSME1,PDGFRL,CAMK1D,SEPT4,VASH1,PJA2,PICK1,PAK6,HELZ2,CYP1A1,ZNF823,STIM1,FOSB,KCNS3,SERINC2,PIK3CA,IRF2,TACSTD2,ZBTB18,METAP2,ACVR1C,CDYL,BNIP3L,SLC35C1,LDB2,POR,RAB2B,ANKRD10,SH2D3C,PPP2R4,PRDM5,BMP1,MAPK13,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,FGD1,SEMA6B,CDKN1C,SCOC,DHPS,TBC1D1,THEMIS2,PRKAA1,AKAP17A,TXNDC9,APBA1,TNFRSF19,TSPAN7,PSIP1,SH3RF2,MESDC2,CALR,C9orf69,RALGPS2,BHLHE41,VASN,PPP4R1,MSH2,DAPK1,PRKG1,OSTF1,CACNA1D,MAST4,DLX4,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,GFPT1,PRODH,KCNJ12,GCC2,KLK5,CALM1,DCHS1,WHSC1,NPC2,EPHA1,ANTXR1,NFIB,PDE11A,MMP15,AP1AR,PLEKHH2,TJP3,PELI2,PIAS2,MPP2,FAM83D,ARAP1,APPL2,SFMBT1,CABIN1,CDK18,SAMD8,KLK7,ZBTB34,PER3,IFIH1,EHD1,SPRED1,FOXO6,TCF25,DLGAP5,TCTN2,REPS2,THRA,DDIT4L,RALBP1,NDRG1,FTH1,BCL2L1,FLT3,DDR1,ZFYVE9,EPS8L2,EPM2A,APOBEC3B,CD46,NOV,CCNA2,ACAP2,RALB,PDE4D,EPHB4,OSBPL7,TSPAN1,FLOT2,MED30,SEMA3B,DOCK4,FOXJ2,DRAP1,UTRN,CLSTN1,ATP1B1,RAD17,PYGO1,PKMYT1,CBL,ASB13,ITPR3,ALCAM,FZD7,NGFRAP1,TSPAN18,TRIOBP,AREL1,CBX7,COBL,PRKAR1A,DEPDC1,IGFBP6,CENPI,EPS8,NES,CBLL1,PBX3,HERC5,PLD2,SPDL1,EFNB1,FGF19,ADGRB2,HLA-A,WWP2,SCML1,CKAP5,RASSF8,E2F7,GNB5,RNF128,FUT8,DRAM1,CD9,ERBB3,CITED2,TTPA,MSH6,FARP2,TGIF1,PDGFC,ZWINT,ARHGEF28,TCFL5,ZKSCAN2,DIAPH2,FBXO9,YES1,GRTP1,FOS,KIF11,CRTC2,CDK5RAP1,TIMP3,FGFR2,TBX18,RIN3,RYK,ERAP1,RABL6,LRRK1,FZD5,ESPL1,MELK,RGMA,CCNC,FAF2,CRYM,VARS2,COMMD5,MAP1LC3B,ERP29,SLC8B1,TRIM68,HTR1D,EPCAM,ZFYVE16,SIPA1L2,RAB15,HSF2,CDKL5,ARHGEF37,SIVA1,TRPC1,ASH2L,CTTN,MYRIP,IL1RAP,SP5,CYP1B1,NLRP4,CXXC5,CENPA,ASXL1,ITCH,USP18,ARHGDIB,TYSND1,GPRC5B,HPSE,MADD,TDRD7,CAB39,ZNF165,SP6,GLA,CHPT1,NRGN,CAPN1,NR2C2,PCSK5,LASP1,ARAP3,PPP1R2,SERPINE2,ZNF395,PPP1R12A,BVES,ETV5,ASB9,CALM3,TEC,ADAMTSL4,DUSP5,QSOX2,SPP1,NOXA1,FAM20C,PFKL,OCRL,PRKCI,SUCO,BRAT1,NPTN,HLA-C,C10orf54,ZRANB1,ETV7,CCDC88A,MDFI,ELK3,PDE5A,KIAA1109,NUBP1,C3orf58,RANBP9,RHPN1,SOX13,INSR,TMEM30A,SH3BP4,RAB31,DCUN1D1,NXPH4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,AFAP1,DRD1,CCNE2,LMO7,LZTFL1,SORBS1,PAX6,HDAC11,SOD2,PDIA5,COL18A1,IL27RA,MRAS,OSR2,PHLDA1,EXT2,MXD1,SAP130,ZNF687,ARTN,KIF14,REEP1,FABP6,ZBTB49,DIXDC1,ECE1,EPB41L4B,NFKB2,UPF3A,EBAG9,CKS2,CHP1,SOAT1,RFK,PTPRU,GLO1,CD40,CDC25C,CASP4,PDHX,ARHGAP35,SOCS3,HSF4,JADE1,STAT6,SECTM1,TLE1,PTBP3,SPTBN5,RCAN2,MAD2L1BP,ABCA1,GLIS3,FBLIM1,GCLM,TSPAN15,ARHGEF11,SH3D19,CIT,ARHGEF7,SERPINB9,TGFBR1,TRIB2,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,LLGL2,BMP7,MYCL,TOX2,ZDHHC13,ACTA2,H2AFY,KANK2,RPGR,MYO5A,DCAF6,WNT10B,SYBU,RC3H2,RGCC,RUNX3,NDRG3,TCEAL8,FOXL1,LEPR,LEMD2,ARHGAP24,CTSL,CD8A,CASP7,SWAP70,RND3,CTSV,SPINT2,RAP2C,DTX4,UACA,ARRB1,ZMIZ1,AHR,RAB3IL1,CD33,ABCG1,NGEF,DOC2A,ACACB,TRIM24,ADD1,IL15RA,TRIM5,DNAJC3,SMARCAL1,FBXO2,XIAP,CACNA2D2,NRG2,LGI3,IL18,MORF4L2,SYTL4,CA8,KIF26A,BARD1,PHF1,TP73,CALM2,DAPK2,WEE1,ZYX,ARHGAP42,PSMD1,TGFBR3,RGS12,AP1M2,CABP1,ALDH1A3,PPP1R16A,KLF3,SEMA3G,PIK3CD,APOBEC3G,VPS11,SMARCA2,TNIP1,SH3BGRL,SPRTN,LOXL2,F12,ICMT,PPP1R14C,MYOM1,PGF,CAMK2N2,GRID2IP,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,ARF6,LSM14B,E2F8,PDPR,GAB1,HOXC13,NFKBIE,TMTC3,NUAK1,CYP2J2,SOX9,ZNRF3,MERTK,LMNA,ELF3,WDFY1,FAM13B,NEK2,NCAM1,SALL4,STAT4,MYBL2,CALCRL,PLS1,SRSF5,ILK,MEST,TP53INP2,RHOB,DCP2,STK17A,PTPRF,NCOA3,SEMA4D,HTT,SETD3,ITPR1,OSMR,AURKA,MDH1,NDE1,ARPC2,TRPC3,ZNF502,SERPINB1,RPS6KA3,XDH,EGLN1,ARHGAP11A,MTM1,GRHL2,ACTR8,RGS20,WDTC1,PKP2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,CCND1,RNF220,SP100,DACT1,RTKN2,ACSL4,RAB27B,ARL4D,CDKN2D,SCN3A,RNF169,ENPP4,SSH3,CAMSAP3,PSRC1,LGALS8,NRBF2,FZD4,SYNE2,NUSAP1,CDCA2,PXYLP1,RAB38,IRS2,PEX5,STX10,SLC9A6,WWTR1,SIPA1L1,PLEKHG1,INPP4B,TRABD2A,RGS14,GEN1,ARNT,FARP1,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,RASSF7,PDIA3,GMCL1,ANO9,PKN1,KCNC4,ETS1,GSTP1,ARHGEF40,TSPAN17,HOXB2,TIPRL,SRPX2,ICAM1,NEO1,PDIA4,CAPN2,CXCL16,ANK1,IRAK1,CTSC,KCNK5,MCF2L,PLEKHF1,ADAM15,TMBIM6,WWP1,ZNF230,MAPK11,ITM2C,TPCN1,S100A6,TMX1,CRTAP,HCN3,AMOTL2,POU6F1,FMN1,CTNNAL1,BCL9,RAPGEF2,EIF5A2,GRIN1,EMP3,FAM109A,NEURL1B,SKA1,ABLIM2,TXK,PITX2,BTG1,KIAA0141,ACVRL1,NR1D2,ATXN7L3,ZFP30,ARFGAP3,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,FOXA1,MYL9,SIGIRR,UNC93B1,TRIM2,AGRN,CUL4B,EPHA4,SUDS3,NDC80,TP53I11,HDAC6,PDGFB,SDC1,PCNA,SHC3,DDHD2,ELF5,DUSP10,TNFRSF18,RGS5,MYBL1,S100A13,NEB,ZNF462,PCGF5,CD55,ING1,MCTP1,CITED4,C12orf65,EZR,TNFAIP8L1,ERP44,KLK6,PRKRA,ANLN,IDH1,ZBTB7B,CLCN2,CDK1,VCP,PLEKHB1,RHEB,OPTN,DPYSL3,IRX3,PLCH1,TBC1D17,WIPI1,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,POMT1,MAFF,PRKAA2,BMF,HLA-F,UBASH3B,RACGAP1,DOCK11,DHRS3,IL18R1,SSX2IP,CORO1B,BMP2,RB1,VASP,DAZAP1,IGF1R,GATA2,PAK2,MDFIC,PLCB2,PSMA5,CYP26B1,CORO2A,SPATA13,TCF7,EIF2AK1,IFIT3,G2E3,MAPKAPK2,PVRL2,ITGA7,CSF1,LTBP2,ATP1B3,CTBP1,IFI6,RNF146,KCNAB3,AVPI1,NF2,UPF3B,FOXM1,P3H2,DGKA,ZNF28,ERBB2,CCDC68,RASGRP3,SLC7A2,CCNL1,LPIN3,CYP26A1,PER2,CDK14,RAD23A,ATP6V0B,SRPX,PLCG2,LHX6,SCN2A,EGLN3,GM2A,DVL2,CTH,SIRT1,TIMP2,TCEB2,FIGNL1,S100A4,CDC20,MYL12A,MYPOP,DNAJC10,DUOX1,ATP1A1,PTK7,PSMD3,ZBTB6,AIFM3,CNEP1R1,ZNF701,ZC3HC1,PACSIN2,MACC1,CD63,ADGRG1,DAP,GABRG2,PSMD10,SELL,NKRF,JAG2,CRABP2,PPP2R3A,GBX2,SLC35B4,BUB1,KLF9,HEXIM2,FAIM,CAMK2G,TLE6,PSMB4,NR3C1,IFITM3,AMFR,LITAF,PPARA,CAPNS1,CARD19,TRIM35,FXR2,PELI3,AKAP3,BORA,BCAR1,MAPK8IP1,PRDX4,CD83,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,NMI,NETO2,PPP2R3C,PKD2,SPCS3,NDFIP1,TBC1D4,UBE2C,GAA,ACVR1,PPP4R4,FAM129B,ATP8A1,KLC2,TAP1,GATA3,PLXNA1,CCNB1,PLA2G16,SLC20A1,FAM101B,ELMOD2,RIC1,CENPN,NCS1,SESN3,CTGF,ELMO2,ZFP36,RGS3,IL31RA,ATRNL1,PACSIN1,RCAN3,TFG,PBK,CASP9,NBPF3,AGO4,PIF1,AURKB,CCNF,SAV1,SLC25A5,ZFAND5,ARHGEF26,ULK2,SGPP1,AHRR,HLF,SLC25A4,AREG,PLK2,TBX1,NKD1,FAM110C,SARAF,EIF4EBP2,TMEM8B,UNC5B,TRAF5,LZTS1,DLAT,DDX58,KLF2,INPPL1,CDK17,HLA-E,DGKQ,SLC25A27,KIF23,SLC1A3,NOTCH2,KIAA1161,BMP2K,MECOM,ITGA3,CYR61,SNX18,PIK3AP1,NECAB3,OPN3,SORL1,TNFRSF12A,CD70,PIKFYVE,TSPAN33,RIMS2,EEF1D,TMED2,EPB41L5,QSOX1,MMD,ZNF84,MFI2,TBC1D8B,B9D2,MICB,AMER1,ANO6,PIP4K2C,KCTD20,CYFIP2,KDM3A,FBXO10,RASA1,STX3,FAS,DGKH,GABRD,SERTAD2,PRKAG2,CSNK1G1,NAB2,TCEAL4,FGD6,NR4A2,EFNA1,MAP3K5,IRF1,PLA2G4A,PLEKHG3,ELK4,ARMCX3,NLRX1,TRIP10,S100A11,RPS6KA1,IQGAP1,SUZ12,CAST,IRX4,CD274,EGR3,AIFM2,MNS1,GNB2,APLP2,ZNF75D,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,IFIT1,LGMN,NR2C1,TMBIM1,TBC1D10B,CDKN2AIP,CAPN6,DMTN,COX11,SLC11A2,PRKCQ,H2AFV,SP4,ZNF469,PRDM11,EPHA10,ZNF641,FYN,JAK1,PPP2R5A,STK26,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,NR3C2,ATMIN,DENND5B,OTUD5,WASF3,ARHGEF3,PCOLCE,ARL4C,GPR180,APOBEC3H,SPR,LGALS3BP,TEAD3,SIX4,RND1,SNTA1,FAM111A,OXCT1,PPP1R10,PTEN,CENPJ,PRC1,SGK3,ATP8B1,SLC44A2,ERCC2,CNOT6L,MAP3K7,GFI1,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,ARAP2,CASK,MPP1,DENND1B,TEF,VAMP3,FURIN,GPLD1,NUCB1,RGS9,RCBTB2,PRDX3,SERPINB5,GRIN2D,GPER1,ARSB,CPEB2,USP16,JARID2,EXPH5,EMX1,LTBP1,CASP3,ST13,CAMKK1,KIF2C,TAF6L,CACNB4,DNER,KREMEN1,DENND2D,SH3KBP1,PTCHD4,ARHGEF10L,NKAIN3,GRHL1,ZCCHC12,TSPAN6,DPYSL2,PHTF1,DLG1,CAPG,AKR1B1,RAB20,RP2,MYH14,ARNT2,SLC39A10,PTPRE,RASGRP1,SOD1,TRIM8,SYNE3,ASCL5,STRIP2,RNF165,ROR1,STK17B,ADRBK2,EDNRA,SEC14L2,MDK,CXXC4,NEIL1,ZNF114,ARHGEF19,IARS2,ADIPOR1,APBA2,RAP1GAP,PSMC1,MIIP,PPP2R5D,GRN,PIFO,LRRFIP2,ATP6V1E2,PHLPP1,ZNF432,CA2,LRRN2,KCNN4,EBF4,DIAPH2-AS1,FNIP1,FXYD5,ZNF692,KNTC1,RFX5,ACAD8,LRIF1,ALS2CL,HP1BP3,OXR1,HMG20B,FBXO8,EGFR,FECH,GNAS,BCAR3,NUDT16,TSC1,ONECUT1,PLPP3,CGREF1,NFKBIA,CDCA5,RHOBTB2,EGFL7,YOD1,KLF7,PROM2,GAS2L1,SLC25A24,SPC25,IL15,SLC2A8,PSME2,TDRKH,MICALL2,PATL2,ARHGEF16,SS18,SVBP,SETDB2,FRYL,SMO,GOT1,TWIST1,STEAP3,APIP,F2R,PDIA6,HSPA2,FRS3,MAP3K3,ZNF525,TAF5,BAG4,KREMEN2,ERBB2IP,DUSP4,SNAPC2,DOCK5,MAP3K6,BHLHB9,PEX2,OVOL1,CANT1,PLXND1,AKNA,SGOL1,LIFR,PPP2R2D,CBX4,ANXA3,SORT1,FRMD6,LRP4,MIER3,AES,NOTUM,ZNF212,IRF2BPL,IL17RB,SNX13,ADORA1,KIAA0319,CKS1B,BRD7,MXD3,IQGAP3,SUN2,ADAM17,RAB3B,CENPC,ASPM,NR4A1,GCLC,DEPDC4,MBNL3,MPV17L2,MAP1B,HLA-B,DHRS2,PRCP,UBE2D2,TADA2B,HOXB13,GEM,ATP6V1C1,SOX8,L1CAM,ZNF596 |
| 7.519e-05 | -9.50 | V$NGFIC_01 | MSigDB lists | V$NGFIC_01 | 243 | 58 | 17758 | 2588 |
LASP1,CDK17,CEP70,PPP1R12A,HOXB7,UBASH3B,EGR3,TP53I11,BAHD1,PDGFB,SPTB,SH3KBP1,HDAC9,SAP130,CDKN2C,TFAP4,APLP2,RALGPS2,ZCCHC12,SH3BP1,WDR44,ICAM5,KLF3,RRBP1,KCNS3,BCL6,CNNM4,TNFRSF12A,CRY2,ERBB3,CNOT6L,RASGEF1A,NTN1,SMYD5,C9orf72,DVL2,SUN2,ATL1,KREMEN2,GRIN1,NFE2L1,CLSTN1,RGAG1,SLC25A5,PNKD,RHOB,PITX2,CRTC2,MAN2A2,CAMK2N2,CORO1C,MADD,PITPNA,MAP3K5,PLOD3,STARD13,NRGN,RPS6KA3 |
| 7.558e-05 | -9.49 | RHOA (ras homolog family member A) | protein interactions | 387 | 143 | 41 | 16036 | 2547 |
ARHGEF3,PPP1R12A,ARHGEF11,CIT,DGKQ,PSMD10,RHPN2,TGFBR1,PKN1,PRKACA,KTN1,DIRAS3,SH3BP1,DPYSL2,MCF2L,CDKN1B,TRPC1,RPN2,DVL2,RASGRF1,RHOA,ARHGEF28,EZR,ARHGDIB,PRRC1,ICMT,SLC25A5,RHPN1,ARHGAP35,FAS,CNTNAP1,PLCG1,MPRIP,ITPR1,NFKBIA,DCUN1D1,SERPINB5,PLD1,PLIN3,DEF6,ARHGEF4 |
| 7.563e-05 | -9.49 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | 135 | 37 | 17758 | 2588 |
FAM171B,KIF3C,ARAP3,DLGAP5,HJURP,PTTG1,NES,AKAP17A,CCNB1,BARD1,SH3KBP1,TOP2A,RAB15,MZT2A,NUP210,IMPAD1,NECAB3,PRC1,BUB1,RNASEH2A,IQGAP3,SMC4,FAM69A,CKS2,OLFML2A,KIF20A,ASPM,NUSAP1,BOLA3,UAP1,FAM64A,AURKA,DYSF,CENPE,ATP6V1C1,CCNB2,UBE2C |
| 7.580e-05 | -9.49 | GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_UP | MSigDB lists | GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_UP | 165 | 43 | 17758 | 2588 |
PRKAA2,IER5L,DYRK3,SSH1,EPAS1,AASS,EPHX4,DNAJB11,BCL2L1,CDK14,IL17RB,GNS,LRRC45,WEE1,UBE2T,LLGL2,DOK4,N4BP3,SLC30A6,PLEKHF1,F2R,ZNF365,TGIF1,TIMP2,MARK1,GCLC,PTPN9,LPGAT1,FHL2,NUSAP1,ATP1B1,DPYSL4,STX3,CORO1C,SETD3,WWTR1,ARFGAP3,LSM14B,REEP4,UBE2C,CDAN1,SNX30,ADAMTS16 |
| 7.585e-05 | -9.49 | GNF2_RFC3 | MSigDB lists | GNF2_RFC3 | 40 | 16 | 17758 | 2588 |
HMMR,FOXM1,ASPM,NDC80,KIF11,CDK1,FANCI,TOP2A,CCNA2,RANBP1,CKS1B,CENPE,UBE2C,MSH6,CKS2,SMC4 |
| 7.662e-05 | -9.48 | polysaccharide metabolic process | biological process | GO:0005976 | 81 | 26 | 16441 | 2455 |
PGM1,GAA,B3GNT2,PPP1R2,UGP2,AKT1,CALM1,CALM3,PYGL,MGAM,NANS,EXT2,GLT8D2,EPM2A,PER2,CALM2,PRKAG2,IL6ST,CSGALNACT1,GYS1,PGM2L1,PPP1CB,B4GAT1,PPP1CA,PHKA2,PHKG2 |
| 7.687e-05 | -9.47 | G2/M DNA replication checkpoint | REACTOME pathways | R-HSA-69478 | 5 | 5 | 8202 | 1235 |
WEE1,PKMYT1,CCNB1,CCNB2,CDK1 |
| 7.703e-05 | -9.47 | RUIZ_TNC_TARGETS_UP | MSigDB lists | RUIZ_TNC_TARGETS_UP | 150 | 40 | 17758 | 2588 |
GRN,KIAA1462,ATP9A,ZCCHC24,COL18A1,KCTD12,COL4A5,GDF15,TRIB2,SEPP1,PHLDA1,LTBP3,SPP1,CTSC,METTL7A,BCL6,KLF9,HLA-C,ACSL4,CTDSP2,SAT1,BNIP3L,BTN3A2,PDE5A,LDB2,EDNRA,GLCE,IL1R1,BTG1,WIPI1,SCG2,PLK2,LRIG1,CSGALNACT1,ARRB1,CTSA,LTA4H,ST3GAL1,IFIH1,GOLGB1 |
| 7.706e-05 | -9.47 | ZHU_CMV_24_HR_UP | MSigDB lists | ZHU_CMV_24_HR_UP | 92 | 28 | 17758 | 2588 |
PLA2G4A,MX1,REC8,CD55,B3GNT2,ENO2,TRIM5,NR4A1,HLA-E,TAP1,GMPR,BCL7B,NUBP1,EMP2,RAB2B,SCARB2,RB1,NFKBIA,RANBP1,TRIM21,IFIT1,PIM1,MANF,ATP6V1C1,PSMC1,IFI6,IRF1,TUBA4A |
| 7.711e-05 | -9.47 | IVANOVA_HEMATOPOIESIS_MATURE_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_MATURE_CELL | 270 | 63 | 17758 | 2588 |
LAMP1,OTUD5,CMAS,GOLIM4,CCDC109B,ADD1,CPEB4,CTSB,HEBP1,CAST,ATP8A1,CDCA3,C5orf30,RAB6A,MAP1LC3B,FAM46C,LBR,TSPAN17,BMP2K,MXD1,ATG4A,MARCH8,SNX13,CCNA2,KHNYN,KLF3,PRC1,ACTA2,MARCH2,LGMN,ANKRD9,TMX1,GPX4,GCNT1,TRAK2,CPD,TMCC2,LAMP2,PQLC3,NR3C1,MPP1,EIF5A2,HSPA12A,SERTAD3,BNIP3L,STRADB,HTATIP2,UBAC1,STK17B,C18orf8,EGFR,G2E3,ENDOD1,DCAF10,NAAA,PI4K2B,SERTAD2,WIPI1,DCK,OTUB2,ADIPOR1,KLF11,SLC25A38 |
| 7.778e-05 | -9.46 | small molecule metabolic process | biological process | GO:0044281 | 2269 | 400 | 16441 | 2455 |
SLC35D2,ACACB,GAA,TXN,HSPG2,AASS,AK7,TMEM86B,SLC25A13,PNPLA2,HEXB,CACNA2D2,MMADHC,PSME1,PLA2G16,OAT,CA8,CHST2,CALM2,HELZ2,TYMP,CYP1A1,PSMD1,CTGF,CYP2S1,ALDH1A3,SLC46A1,RDH14,KCNS3,SERINC2,PIK3CA,FUT1,AOX1,DNM2,PPP1CA,PIK3CD,ACOX2,APOBEC3G,CDA,MGAM,PRKAR2B,ICMT,SLC25A5,PNKD,TP53I3,CYP4F3,POR,SLC44A3,SGPP1,KDSR,ENPP1,PLCG1,SLC25A4,BMP1,DHTKD1,ITPKA,PDPR,DLAT,INPPL1,ALDH6A1,DHPS,CYP2J2,PRKAA1,SLC25A27,NDUFA4,ISYNA1,SLC1A3,COX6C,PDXDC1,GNS,ATP5H,BDH1,CTPS1,MSH2,PCYOX1,SORL1,CACNA1D,PIKFYVE,NDUFA12,NUP85,PHKG2,MCCC2,EPHX1,GFPT1,FADS2,PMPCB,PRODH,B3GNT7,ADCK3,LPGAT1,CALM1,ERO1A,FHL2,PYGL,CALCRL,NPC2,PKM,KDM3A,PCTP,SPTLC2,PSMA4,CYB5A,PDE11A,NT5C2,PRKAG2,HTT,FAAH,DCK,ITPR1,MPP2,DGAT2,MDH1,SAMD8,B4GAT1,NUP58,XDH,EGLN1,PLA2G4A,MTM1,SLC2A4,NQO1,PAPSS2,INPP5D,IQGAP1,ETNK1,WDTC1,MGST2,PRKACA,NUDT12,MOCS1,CYP39A1,GNB2,EPM2A,CDS1,APLP2,XYLT2,PDE4D,ACSL4,DLG3,PHKA2,LGMN,SULT2B1,GPX4,ENPP4,SEC23A,PFKFB2,AGPS,CYB5R2,SAT1,PANK1,PXYLP1,ATP1B1,ITPR3,IRS2,ALDH3B1,ACAD10,INPP4B,PNPLA6,PPP1CB,SLC27A1,PDXK,HS3ST3B1,B4GALT3,SLC27A3,PRKAR1A,GALK1,GCAT,SDC4,APOBEC3H,PLD2,SPR,GSTP1,SGPL1,FUT2,OXCT1,SLC27A6,ARSG,PTEN,GPC3,FDXR,FUT8,ATP8B1,ECI2,SLC44A2,ERCC2,AK3,TTPA,NCOA2,CRTAP,OPLAH,PCCB,ALDH2,CASK,SHMT1,B3GNT2,PLSCR1,MPP1,PIK3R1,ELOVL3,AK4,BLVRA,ARSK,CPTP,GPLD1,CRTC2,LDLRAP1,ACADSB,CTNS,SLC35B3,DBI,PLA2G15,ABCB1,NR4A3,PGM2L1,CMPK2,NUP37,ARSB,OCLN,ACOT7,NMRK1,UGT8,AGRN,CRYM,CPT2,MCCC1,PHOSPHO1,VARS2,ITPR2,GALM,CDIPT,CACNB4,SDC1,ECI1,ABCD4,CHPF,INPP5E,NUP210,ENTPD4,GRHL1,P4HB,IMPAD1,PSMC2,PAPSS1,SLC44A1,DLG1,AKR1B1,TECR,CYP1B1,CERS2,CCBL2,IDH1,MRPS36,VCP,TCN2,MAN2A2,PLCH1,PI4K2B,HS6ST1,NEIL1,AGPAT2,HPSE,UEVLD,P4HA2,IARS2,ADIPOR1,PIK3C2B,GLA,CHPT1,PSMC1,PPP2R5D,HS6ST3,PRKAA2,FAM213B,ELOVL7,ABCG2,ASL,PSMD7,CALM3,ASAH1,B4GALT4,DHRS3,CA2,CES2,PFKL,OCRL,BRAT1,AHCY,FAR2,ACAD8,GAD1,PLCB2,ALDH3A2,PSMA5,ABCC1,CYP26B1,CHSY3,PDE5A,PDK3,NUBP1,AMDHD1,GLCE,FECH,GNAS,MAPKAPK2,DHDH,NUDT16,ONECUT1,SLC6A6,FA2H,PLPP3,PRPS2,CTSA,PLD1,APOL2,UGP2,PSME2,XYLT1,GMPR,SLC7A2,LPIN3,EXT2,CYP26A1,PER2,CYP4F11,PLCG2,FABP6,SRR,GYS1,GOT1,APIP,MINPP1,ETHE1,EGLN3,FAR1,GM2A,CTH,CHP1,SULF2,SOAT1,AKT1,RFK,FIGNL1,ACO1,GLO1,PDHX,DUOX1,PTGS2,ALDH5A1,ABHD12,PSMD3,PEX2,MAOA,CYP2U1,ST3GAL1,LTA4H,NDST3,ABCA1,MAN2B2,CMAS,GCLM,CDS2,ENO2,SCD5,HAL,BLVRB,GNE,PSMD10,CRABP2,DSE,LBR,ZDHHC21,GALNS,ALDH7A1,ABCD1,HMGCL,SYK,MYO5A,FAH,HMMR,B3GALT6,PGM1,PSMB4,GUSB,GCLC,PPARA,OGDHL,NADK2,GGH,RNPEP,LEPR,PRDX4,FUCA1,DDAH1,MARC1,NAT1,CSGALNACT1,GLB1,ACADM,PTGES,ABCG1 |
| 7.785e-05 | -9.46 | small GTPase binding | molecular function | GO:0031267 | 244 | 59 | 16491 | 2452 |
EXPH5,PIFO,RALBP1,RUSC2,NDRG1,IQGAP1,EPS8,RASGRP3,SYTL4,NCKAP1,PKN1,MICALL2,DOCK11,CCDC64B,RIC1,ARHGEF16,SYTL2,RABGGTA,PAK6,ACAP2,MLPH,NOXA1,LLGL2,CDKL5,OCRL,PAK2,RANBP1,EXOC8,TNPO2,SORL1,IQGAP3,MYRIP,C9orf72,SYTL3,MYO5A,RIMS2,MYO5B,DOCK4,SOD1,DIAPH2,STRADB,RANBP9,OPTN,PEX5,RAB11FIP2,CORO1C,RIN3,SH3BP4,RAB11FIP1,TRIOBP,MAP3K11,FGD6,ARHGAP4,ITPKA,RAP1GAP,ABCA1,DOCK9,EHD1,FGD1 |
| 7.812e-05 | -9.46 | frontal_lobe | COSMIC cancer mutations | frontal_lobe | 74 | 24 | 17775 | 2585 |
SCN5A,NF2,AKT1,RET,TP53,ESYT1,IDH1,GNA11,EGFR,GNAS,CDKN2C,CTNNB1,FAT4,PTEN,FGFR2,ICAM5,FDXR,MSH2,PIK3CA,SMO,CDKN1B,SYK,DCBLD1,MSH6 |
| 7.819e-05 | -9.46 | single-organism localization | biological process | GO:1902578 | 3285 | 561 | 16441 | 2455 |
DOC2A,ACACB,ADD1,IBTK,GRIK2,SLC25A13,MCOLN3,CACNA2D2,TRAPPC8,TGOLN2,LGI3,BAIAP3,SYTL4,SNX9,SLC35E4,TP73,CALM2,NAPG,PQLC2,AP1M2,SLC46A1,ATP13A3,DNM2,TINAGL1,PIK3CD,TMEM37,CPE,TUBA4A,VPS11,UXT,KDELR3,PRKAR2B,ICMT,RNF19B,SLC44A3,ENPP1,PLCG1,LIMK1,ATP7B,TRAF3IP1,NOD2,RNASEL,ANXA11,SCN5A,NFKBIE,SEC61G,SLC36A4,GPSM2,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,RIMS3,ATP5H,FBXO7,PCYOX1,CADPS2,CNGA1,PANX2,NUP85,PPP6R1,NAGPA,UFD1L,SLC37A1,ERO1A,CALCRL,PLS1,SRSF5,PCTP,SFXN5,RHOB,CYB5A,CACHD1,SCARB2,SLC4A4,TIMM8A,HTT,ITPR1,NDE1,ARPC2,TRPC3,NUP58,XDH,MTM1,CCDC109B,APOO,PKP2,PRKACA,CCND1,SCNN1A,CDH1,ACSL4,ARL4D,DLG3,RAB27B,SCN3A,SNX8,SEC61B,PSRC1,FZD4,SYNE2,VPS4B,NUSAP1,RAB38,PEX5,STX10,CORO1C,SLC9A6,AXL,SLC25A30,TAOK2,HSP90B1,HABP4,FLOT1,BTN3A1,PDIA3,CTSZ,ANO9,KCNC4,IFT27,SLC25A43,TSPAN17,PDIA4,SLC25A45,ANK1,ADD3,SLC27A6,CTSC,FAM160A2,KCNK5,BAX,KLC3,PLEKHF1,WWP1,TPCN1,S100A6,HCN3,LCA5,RAPGEF2,PIK3R1,MRS2,GRIN1,RAB3IP,FAM109A,NEURL1B,RGPD5,LDLRAP1,RPL12,RAB11FIP2,SYT7,SLC35B3,NR4A3,ARFGAP3,SSNA1,ITGAV,CENPE,NUP37,CD81,USF2,SRSF9,CYBRD1,AGRN,ARFGEF1,NDC80,F11R,ITPR2,HDAC6,PDGFB,NUP210,CTNNB1,ARL1,LMAN2L,SLC44A1,ABCA2,TLN2,ANO4,TRAM1,S100A13,KCNIP3,CELSR2,EZR,ARFRP1,ESYT1,CLCN2,VCP,OPTN,TRIM9,TBC1D17,KCNMB4,WIPI1,RAB11FIP1,KPNA2,PIEZO1,TC2N,PRKAA2,FXYD3,SLC22A31,RACGAP1,RAB6A,NCKAP1,ANO1,PGAP1,SSX2IP,TIMP1,GATA2,ICAM5,KIF13B,SLC30A6,EXOC8,SELK,ABCC1,STRADB,SCRIB,EIF2AK1,ZDHHC3,MFSD2A,SLC2A6,ZDHHC7,LTBP2,ATP1B3,PLD1,NIPA1,KCNAB3,UPF3B,TP53,P2RX7,SLC7A2,EMP2,BCAP31,SDF4,SYTL2,TTC21B,PDGFA,ATP6V0B,SRPX,PLCG2,BCL6,ZDHHC23,SCN2A,LMAN1,GM2A,PPIF,CLCN3,AKT1,ACO1,DAG1,ATP13A2,TAPBP,ATP1A1,MAOA,CHMP4B,SYT13,RPL22,COPG1,PINK1,MFSD14B,TRAPPC10,CD63,CDCA8,GABRG2,PSMD10,AIP,VPS26A,SLC9A2,ZDHHC21,M6PR,CDK16,SLC35B4,SGK1,ABCD1,CPLX1,SYK,SLC45A3,CAMK2G,ATP2B1,P2RX4,HES1,FBLN5,CRB3,PPARA,PRICKLE1,COL7A1,AKAP3,BBS2,SCRN2,SERPINA1,SCG2,TMC5,PKD2,SPCS3,NDFIP1,ARHGEF9,LAMP1,SUN1,GAA,SLC35D2,TSC22D3,ATP8A1,KLC2,TAP1,GATA3,CCNB1,SLC20A1,RIC1,NCS1,SLC9A7,PICK1,CTGF,STIM1,ELMO2,OSBPL3,PIK3CA,SERINC2,KCNS3,STEAP2,SNX16,PACSIN1,TFG,XKR8,LAMP2,ORAI2,BNIP3L,SLC35C1,KIF13A,SLC17A5,MCFD2,SLC25A5,SPNS3,SFXN1,SLC25A4,AREG,GNPTAB,SARAF,SLC31A2,F2RL1,SLC25A27,NDUFA4,SLC1A3,APBA1,CALR,DOPEY2,SNX18,NECAB3,SLC16A6,RPL39,SORL1,CACNA1D,PIKFYVE,SYTL3,RIMS2,TMED2,TSPAN33,TRAK2,KCNJ12,GCC2,PMPCB,MFI2,CALM1,ANO6,NPC2,ATP8B3,CYFIP2,STX3,GABRD,AP1AR,SLCO4A1,PRKAG2,WDR19,ZDHHC20,SLC4A3,HOOK1,NRBP1,EHD1,PKD1L2,MFSD3,PLA2G4A,KIF3C,SLC2A4,DLGAP5,THRA,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,ZFYVE9,CNNM4,TNPO2,CDKN1B,OSBPL7,FLOT2,ATG4D,TBC1D10B,MYO5B,SLC5A11,SEC23A,COG2,DMTN,COX11,KIF1C,SLC11A2,ATP1B1,ITPR3,ATP10D,OSBPL2,FYN,DDOST,SLC27A1,RAB29,PRKAR1A,DENND5B,SLC16A14,SLC41A1,ATP9A,ARL4C,PLD2,CYB561,SPDL1,COX7A2,SLC25A36,PPP1R10,CD9,SGK3,SLC44A2,ATP8B1,TTPA,SPRY2,SLC16A5,NCOA2,CASK,ZC3H11A,FURIN,VAMP3,YES1,CPTP,GPLD1,CTNS,FGFR2,SLC25A40,ABCB1,GRIN2D,ARSB,ESPL1,ESYT2,EXPH5,FAF2,CRYM,CPT2,UBE2Q1,MPP5,KIF2C,SLC8B1,ERP29,CACNB4,TMC1,ABCD4,ZFYVE16,RAB15,DPYSL2,DLG1,TRPC1,RAB20,KIF22,SUN3,RP2,SLC39A10,RASGRP1,SOD1,CENPA,SYNE3,ADRBK2,TCN2,EDNRA,KCNK1,PCSK5,GRN,LASP1,PEX6,ETV5,ABCG2,ATP6V1E2,CALM3,CA2,KCNN4,PRKCI,FXYD5,SRP54,SLC12A2,GAD1,KDELR1,MDFI,BTN3A2,STEAP1,MFSD7,EGFR,GNAS,TSC1,SLC6A6,TMEM30A,NFKBIA,CDCA5,SH3BP4,RAB31,PITPNA,SHROOM2,JAK3,APOL2,TOB1,DRD1,SLC25A24,SORBS1,SLC2A8,ABCG4,MICALL2,SVBP,SLC25A48,KIF14,ZDHHC12,FABP6,REEP1,RPN2,STEAP3,F2R,CHP1,SOAT1,BAG4,OSTM1,SLC39A8,AP5M1,ALDH5A1,PEX2,SPTBN5,ABCA1,ANXA3,SORT1,TSPAN15,SH3D19,LRP4,ITGA2B,HMGXB4,TMEM63A,KIF5B,ADRBK1,ADORA1,LLGL2,ZDHHC13,RPGR,SLC35A1,MYO5A,SUN2,RAB3B,ASPM,MAP1B,ARRB1,SLC18B1,MCUR1,ATP6V1C1,ABCG1,SNPH |
| 7.834e-05 | -9.45 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP | 196 | 49 | 17758 | 2588 |
PLA2G4A,DYRK3,ASAH1,KCTD12,FAM101B,ECI1,SIRPA,IER3,CCND1,CA2,GATA2,CST3,CD9,TMEM51,SORL1,TAGLN2,PTPRE,TTPA,IL10RB,TMBIM1,S100A6,CKAP4,IGDCC4,ABCC1,P2RX4,S100A4,STAU2,MGAT4B,LITAF,GGH,DOCK5,PCTP,SPTLC2,GABARAPL1,RASGRP2,ATP13A2,PRCP,PTER,SH2D3C,PLA2G15,APPL2,RAB31,LRRK1,TTC39C,CD81,NRGN,SERPINB1,CPPED1,CD33 |
| 7.834e-05 | -9.45 | GSE17721_12H_VS_24H_LPS_BMDM_UP | MSigDB lists | GSE17721_12H_VS_24H_LPS_BMDM_UP | 196 | 49 | 17758 | 2588 |
CCDC109B,PARP12,S100A11,FAM129B,NDRG1,RASA2,ABCG2,DNAJB11,TGFBR1,PSME1,CCNL1,GRK6,PLA2G16,SPSB1,CAPN2,RCN1,APLP2,ZYX,FLII,RPS6KA2,ITGA3,KCNN4,SGK3,MDFIC,ARNT2,ECE1,CTTN,TSPAN33,SMC4,CORO2A,KIF1C,KLK6,PRRC1,SAV1,FNDC3A,IFIT3,CASP4,NCOA3,KBTBD2,NFKBIA,NAB2,MAP3K11,OVOL1,CHMP4B,SERPINB6,ITGAV,RGS14,SRSF9,IRF1 |
| 7.883e-05 | -9.45 | THIOREDOXIN_2 | prosite domains | PS51352 | 35 | 15 | 11866 | 1802 |
QSOX1,DNAJC10,TXN,PRDX3,P4HB,TMX4,PDIA5,PDIA3,ERP44,PDIA6,TXNDC11,QSOX2,TMX1,PRDX4,PDIA4 |
| 7.950e-05 | -9.44 | KEGG_OOCYTE_MEIOSIS | MSigDB lists | KEGG_OOCYTE_MEIOSIS | 111 | 32 | 17758 | 2588 |
CCNE2,RPS6KA1,PTTG1,CUL1,CALM3,ITPR2,CCNB1,PRKACA,CALM2,RPS6KA2,IGF1R,BUB1,PPP1CA,CAMK2G,REC8,PLK1,CDC20,CALM1,PKMYT1,ITPR3,CDC25C,CDK1,PPP2R5A,ITPR1,AURKA,PPP1CB,CCNB2,SGOL1,PPP2R5D,ESPL1,RPS6KA3,MAPK12 |
| 8.023e-05 | -9.43 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | 488 | 102 | 17758 | 2588 |
LTBP1,KIF3C,NCKAP5,KLK10,ST13,HDAC11,PTTG1,TP53,IRX4,GATA3,FAM102B,SLC7A2,OSR2,EGR3,SYTL4,EMP2,BARD1,ZNF385B,SYTL2,KCTD15,UBE2T,METTL7A,PAPSS1,ATRNL1,TNPO2,CDH3,TMEM64,MYBL1,SNX10,TIAM1,SULT2B1,SEMA3B,LAMP2,CELSR2,RIPK2,PTGER4,TFAP2C,NUSAP1,AURKB,ESYT1,CBL,COL12A1,SGPP1,TMEM164,ZNF114,MID1IP1,JAK1,AREG,INPP4B,DHTKD1,HSPB1,STARD13,ISOC1,CD99,GOLIM4,LRRFIP2,FAM189A2,NUAK1,DHPS,PYROXD2,ZCCHC24,FRMD6,COL4A5,GTF3A,NTAN1,PPP2R3A,DAZAP1,CA2,IGF1R,RALGPS2,SLC27A6,PTEN,LYPD6,FUT8,SGK3,ECI2,WWP1,MDFIC,IQGAP3,RIMS2,MYO5A,HMMR,KIF20A,PRSS23,ASPM,SYBU,DUSP23,STMN3,MEST,NFIB,CRISPLD2,MAPKAPK2,ARHGAP24,FGFR2,NAB2,RAB31,TCEAL4,FHL1,CCNB2,UBE2C,L1CAM,JARID2 |
| 8.030e-05 | -9.43 | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN | 191 | 48 | 17758 | 2588 |
SUN1,AVPI1,ARMCX3,PPM1J,CAMKK1,CAST,NDRG1,CTSB,BLVRB,MCTP2,FLOT1,NDRG2,DDR1,NCS1,IER3,RABGGTA,DNPEP,ITGA3,TIMP1,TSPAN6,PAPSS1,ATRNL1,ECI2,TAX1BP3,KLF9,CDKN2D,TLE6,RBMS2,SUSD3,FURIN,PYGL,TNFAIP8L1,PRRC1,CYFIP2,MCFD2,FNDC3A,ZBTB7B,FRMD4B,AMZ2,MAGED2,CARHSP1,PTPRJ,CCDC6,ARRB1,ARFGAP3,GEM,SERPINB1,FAM45A |
| 8.030e-05 | -9.43 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP | 191 | 48 | 17758 | 2588 |
CCDC109B,EPAS1,ELOVL7,NANS,BAIAP3,NCKAP1,DUSP5,SYTL2,CTNNBIP1,CAPN2,DAPK2,FLII,VASN,OSBPL3,AIM1,RRBP1,TAX1BP3,MXD3,AK3,CACNA1D,CTSD,NEB,SYTL3,XKR8,ATG4D,ADAM17,CDYL,FHL2,SPATA13,EMP3,PKMYT1,SNAPC2,ILK,DOCK5,PDIK1L,SPAG1,RASGRP2,ATP13A2,ENDOD1,CASP7,PRKAG2,CDK19,C1orf21,TRAF3IP1,AGFG2,TMEM120A,PPP2R5D,L1CAM |
| 8.030e-05 | -9.43 | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN | 191 | 48 | 17758 | 2588 |
LAMP1,LGALS3,CTSB,HEXB,ASAH1,KCTD12,IL18,BLCAP,CTSZ,DSE,BMP2K,DNAJB9,ATP6V0B,FAM46A,TIMP1,PTEN,CTSC,METTL7A,KCNS3,HMGCL,IL10RB,NAGA,SYK,P2RX4,NAGPA,GCA,VPS11,MCTP1,MMD,CDA,RAB38,FNDC3A,TRAM2,TCEAL4,APPL2,TDRD7,ARRB1,DYSF,ADIPOR1,KLF11,PLXND1,GLA,ATP6V1C1,MAP3K5,PLIN3,PLOD3,ABCA1,CD33 |
| 8.030e-05 | -9.43 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN | 191 | 48 | 17758 | 2588 |
CASP3,LZTFL1,RUNX2,S100A11,PSME2,FAM129B,DAP,CYB561,NENF,PLA2G16,COX7A2,CDKN2C,DAPK2,WEE1,ZCCHC17,DNPEP,SHC3,METTL7A,ATP13A3,RRBP1,TRPC1,RAB20,CTTN,MINPP1,FAIM,EGLN3,F2R,GM2A,S100A6,METAP2,LAMP2,RASGRF1,PQLC3,LITAF,FURIN,CCBL2,HTATIP2,CASP4,FECH,ENPP1,PAFAH1B3,UAP1,AREG,DBI,RYK,STK39,LRRK1,RAD21 |
| 8.030e-05 | -9.43 | GSE3982_MAC_VS_BASOPHIL_UP | MSigDB lists | GSE3982_MAC_VS_BASOPHIL_UP | 191 | 48 | 17758 | 2588 |
PLA2G4A,ARMCX3,IBTK,GCAT,CAST,CD82,CALB2,ETV5,RET,ERI2,ASAH1,TGFBR1,ERP29,SPSB1,PPP2R3A,SCML1,DOPEY2,VASP,IMPAD1,MCF2L,IL6ST,DIXDC1,GLB1L2,MYO5A,EPHX1,CKS2,EBAG9,PPIF,GFPT1,ENPP4,FADS2,BAG4,B3GNT2,TESK1,NRBF2,RC3H2,KDELR3,IDH1,RNPEP,GNA11,BCL10,PROM1,FASTKD1,DDOST,PGRMC1,DYSF,SPRY4,DMWD |
| 8.030e-05 | -9.43 | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN | MSigDB lists | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN | 191 | 48 | 17758 | 2588 |
GRN,PARP12,AGRN,S100A11,GMPR,CALM3,HERC5,CCNL1,HERC6,MAP1LC3B,CENPN,LGALS3BP,H1FX,CALM2,CAPN2,BTG3,PRC1,OAS3,CTSD,S100A6,LAMP3,REC8,MX1,PLSCR1,CTNNAL1,IFITM3,USP18,MICB,SAT1,CALM1,UBE2A,FNDC3A,SPTLC2,RHEB,TCN2,ARF4,FAS,CDCA4,HPSE,C19orf66,PVRL2,H1F0,CDCA5,DYSF,IRF7,CMPK2,PLIN3,IFI6 |
| 8.030e-05 | -9.43 | GSE7852_LN_VS_THYMUS_TCONV_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_UP | 191 | 48 | 17758 | 2588 |
NUDT6,AVPI1,TRIM2,PINK1,TTC39B,LGR4,HLA-E,DNAJB2,ITGA6,SERPINB9,EFHD2,NOTCH2,PLA2G16,IL18R1,RSAD1,RAD23A,UHRF1BP1L,GNS,APOBEC3B,RCN1,SIPA1L2,CYP2S1,RUNDC3B,DAPK1,MAP3K7,OSGIN1,S100A6,GCNT1,PLSCR1,RGMB,S100A4,ZSCAN12,SPNS3,CASP4,DGKE,SOCS3,HLA-B,ENPP1,BTG1,BANK1,LRIG1,NR4A3,PNPLA6,STK39,AKNA,RBM43,CBX7,XDH |
| 8.030e-05 | -9.43 | GSE22886_NAIVE_CD4_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_DC_DN | 191 | 48 | 17758 | 2588 |
GRN,AVPI1,ST14,S100A11,CD63,CTSB,DCAF7,GSTP1,M6PR,ATP6V0B,C7orf49,TM9SF2,CTSC,PLCG2,CST3,DAPK1,OPN3,H2AFY,TAX1BP3,HMGCL,NPTN,SYK,ALDH3A2,LAMP2,LAP3,GCLC,SH3BGRL,NFE2L1,VAMP3,UBE2A,PYGL,IDH1,RHEB,ZMPSTE24,HTT,RCBTB2,PRDX3,GDE1,UTP14C,RAB31,GLB1,GLA,ZMIZ1,AKIP1,SLC31A2,NRGN,ISOC1,PRKAR1A |
| 8.031e-05 | -9.43 | Separation of Sister Chromatids | REACTOME pathways | R-HSA-2467813 | 161 | 43 | 8202 | 1235 |
SPC25,PSME2,CENPI,PTTG1,NDC80,ERCC6L,CDCA8,PSMD7,PSMD10,NUF2,PSME1,KIF2C,SPDL1,CENPN,CKAP5,PSMD1,PSMC2,BUB1,KNTC1,NUP85,PSMA5,PLK1,CENPA,ZWINT,PSMB4,CENPC,B9D2,CDC20,AURKB,SKA1,PSMA4,PPP2R5A,PSMD3,CDCA5,CENPE,NDE1,NUP37,SGOL1,UBE2C,PSMC1,PPP2R5D,ESPL1,RAD21 |
| 8.095e-05 | -9.42 | response to peptide | biological process | GO:1901652 | 590 | 122 | 16441 | 2455 |
SPRED1,SORBS1,SLC2A4,SLC2A8,PSME2,WDTC1,NRG2,ERBB2,RASGRP3,PSME1,PRKACA,PDGFB,SPTB,GNB2,CALM2,PDGFA,ATP6V0B,SESN3,CCNA2,PSMD1,CTGF,SHC3,PSMC2,KLF3,PIK3CA,AKR1B1,CDKN1B,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,SIRT1,RIPK2,AKT1,ACVR1C,PRKAR2B,PRKCQ,ERBB2IP,POR,CASP4,DAG1,RHEB,SOCS3,IRS2,ENPP1,IDE,FYN,JAK1,AREG,PSMD3,NOD2,STAT1,CAB39,SLC27A1,EIF4EBP2,SPTBN5,NRG1,LTA4H,PSMC1,GAB1,RRAGD,PRKAR1A,PRKAA2,KLF2,SORT1,INPPL1,RASA2,CTSB,PRKAA1,PSMD7,ATP6V1E2,CALM3,PSMD10,DUSP5,FGF19,HDAC9,TIMP1,IGF1R,BMP7,PRKCI,ERBB3,NCAM1,CAMK2G,MYO5A,PSMA5,GCNT1,RASGRF1,ADAM17,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PPARA,STRADB,GGH,YES1,BCAR1,PSMA4,EGFR,RASA1,GPLD1,GNAS,TSC1,BTG1,INSR,PRKAG2,FGFR2,FGF18,NFKBIA,RAB31,NR4A3,GRIN2D,NR4A2,GPER1,ATP6V1C1,JAK3,TBC1D4,CPEB2,DRD1 |
| 8.113e-05 | -9.42 | caveola | cellular component | GO:0005901 | 78 | 25 | 17570 | 2579 |
SPRED1,SCN5A,PACSIN2,CTSB,LRP4,FLOT1,ATP1B1,CBL,HDAC6,EMP2,PTGS2,INSR,ATP1A1,IGF1R,CDH1,CTNNB1,CORO1C,SMO,PRKCDBP,SLC27A1,EFNA5,ATP1B3,FLOT2,F2R,DRD1 |
| 8.115e-05 | -9.42 | YAGI_AML_WITH_11Q23_REARRANGED | MSigDB lists | YAGI_AML_WITH_11Q23_REARRANGED | 336 | 75 | 17758 | 2588 |
HSPG2,GRIK2,CAST,SLC25A13,CTDSPL,RET,GMPR,RASGRP3,ITPR2,VASH1,KBTBD11,ERP29,EMP2,CTGF,SHC3,PLCG2,CAPG,AKR1B1,PIK3CD,PPP1CA,IL10RB,NR2C1,CPD,ENPP4,NEK4,COL6A2,PRKCQ,ATP1B1,LCP1,ABR,NFIX,TBX1,WFS1,MMP17,LRIG1,EIF4EBP2,PPP1R2,FAM169A,PSMD7,PBX3,FZD6,HDAC9,DOPEY2,RB1,TAF1B,ATP5H,BMP7,RRBP1,ADAM15,OSTF1,PIM1,SLC16A5,RPGR,ALDH3A2,ELK3,TACC1,MAPKAPK3,NR3C1,GCLC,MICB,PLAUR,AK4,PLS1,YES1,RASGRP2,MAGED2,TIMP3,INSR,SEMA4D,ITGA7,ITGAV,TMEM159,CD81,JAK3,RPS6KA3 |
| 8.165e-05 | -9.41 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | MSigDB lists | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | 403 | 87 | 17758 | 2588 |
CCNE2,KLK10,PAX6,GPR107,ST14,MCOLN3,XIAP,SOD2,MRAS,F11R,ZMYND10,TP53I11,BARD1,IER3,DOK4,MKRN3,CABP1,LHX6,ELF5,DUSP10,CDH3,TWIST1,TACSTD2,ESPN,NFKB2,SCARA3,HSPA2,CYP1B1,MX1,SMARCA2,CD55,CYB5R2,CDA,TFAP2C,RAB38,CDC25C,ULK2,PGF,HOXA9,ZNF165,MAOA,IRF7,EPB41L4A,NRGN,HOXC13,NXT2,MRC2,CDKN1C,GCAT,ZCCHC24,NES,GDF15,SAMD9,RAB6A,CRABP2,S100A2,DUSP5,ICAM1,DIRAS3,RAC2,ADRBK1,LYPD3,CD22,PAK2,TPST1,DAPK1,TMEM51,HLA-C,ULBP2,CYP26B1,PLAUR,MBNL3,SNTB1,IL1R1,HLA-B,TIMP3,SERPINA1,ITGA7,CSF1,NETO2,RAB31,RHOBTB2,IFIH1,IFI6,AHR,ARHGEF4,PHC1 |
| 8.179e-05 | -9.41 | follicular_carcinoma | COSMIC cancer mutations | follicular_carcinoma | 61 | 21 | 17775 | 2585 |
AKT1,RET,PIK3R1,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CTNNB1,CDH1,PTEN,FGFR2,CCDC6,PIK3CA,SMO,TFG,JAK3,PRKAR1A |
| 8.179e-05 | -9.41 | thyroid-carcinoma-follicular_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-follicular_carcinoma | 61 | 21 | 17775 | 2585 |
AKT1,RET,PIK3R1,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CTNNB1,CDH1,PTEN,FGFR2,CCDC6,PIK3CA,SMO,TFG,JAK3,PRKAR1A |
| 8.215e-05 | -9.41 | NUCLEOSIDE_TRIPHOSPHATASE_ACTIVITY | MSigDB lists | NUCLEOSIDE_TRIPHOSPHATASE_ACTIVITY | 212 | 52 | 17758 | 2588 |
RECQL,PEX6,RALBP1,GNAL,ARL4C,SMARCAL1,ABCG2,DHX8,MRAS,RAB6A,SEPT4,GNB2,PICK1,ABCD4,TOP2A,DIRAS3,RAC2,ARL1,MSH2,ABCA2,ATP8B1,RAB27B,ARL4D,MSH6,ATP2B1,ABCC1,RAB3B,RHOA,VPS4B,KIF20B,ARFRP1,PIF1,ATP1B1,GNA11,RHEB,VCP,RHOB,ARF4,DDX23,GNAS,TAPBP,ATP1A1,DNM1L,RND3,ATP7B,PPP2R4,RAB31,ATP1B3,ATP6V1C1,ARF6,PSMC1,ABCG1 |
| 8.215e-05 | -9.41 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | 186 | 47 | 17758 | 2588 |
RUNX2,KIAA1462,ARMCX3,LGALS3,EPAS1,PSME2,SPSB1,KTN1,DUSP5,PPP2R3A,SDF4,PLS3,SPP1,MGAT1,TMEM62,TOX2,PLEKHF1,RAB20,TNFRSF18,F2R,C12orf75,TBC1D10B,XKR8,ABCC1,SUSD3,SOAT1,MLEC,SEC61B,STAU2,LPGAT1,SPA17,GGH,TMTC2,RNF19B,RNPEP,CASP4,FRMD4B,ENPP1,CD8A,MTFMT,GNPTAB,ITPR1,RYK,MLKL,GEM,AHR,EHD1 |
| 8.215e-05 | -9.41 | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | 186 | 47 | 17758 | 2588 |
SUN1,ARHGEF3,USH1C,FAM160B1,FRMD6,DAP,THRA,HAL,ARL4C,GATA3,MGST2,TRIB2,KBTBD11,PARM1,SYTL2,TTC21B,ZFP36,DLG1,IL17RA,MAPK11,TMEM8A,CDKN2D,ALS2CL,SYK,DOCK4,RGMB,KIAA0040,ZC3H11A,TEF,FOXJ2,MFSD2B,TANC1,CD40,FOS,ZBTB7B,ATP10D,NFIX,ATP13A2,LEMD2,PTGS2,ALDH5A1,TBC1D17,HS3ST3B1,ST3GAL1,USF2,CPEB2,KLF7 |
| 8.215e-05 | -9.41 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN | 186 | 47 | 17758 | 2588 |
PLA2G4A,IL15RA,TRIM5,PSME2,HLA-E,HLA-F,TRAF2,TAP1,SELL,PDIA3,CUL1,BTN3A1,PSME1,SEPT4,LGALS3BP,RCN1,TYMP,RALB,PSMC2,AIM1,APOBEC3G,ERAP2,FAM69A,RFK,LAP3,GCLC,DENND1B,SNTB2,LPGAT1,PLEKHO1,CDA,PSMA4,CASP4,FAS,FNTA,NMI,PRPS2,SECTM1,STAT1,NOD2,MAP3K11,ERAP1,IRF7,IFIH1,ISOC1,APOL2,TMEM131 |
| 8.215e-05 | -9.41 | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | 186 | 47 | 17758 | 2588 |
CDS2,REPS2,HEBP1,RPS6KA1,ERBB2,PSME1,TRAPPC8,SLC7A2,INTS8,SNN,ICAM1,UHRF1BP1L,ZYX,SH3D21,TYMP,SP100,IRF2,RAB20,TMEM8A,CNPY3,FLOT2,DUSP1,MAP3K3,THRB,DOCK4,TRIM8,MOSPD2,KIAA0040,NRBF2,IFITM3,CDA,MGAM,AKAP3,FOS,SPTLC2,HLA-B,MSL1,PPP2R5A,STX10,SECTM1,STAT1,DYSF,PITPNA,EIF4EBP2,RTN3,PTGES,CPPED1 |
| 8.215e-05 | -9.41 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN | 186 | 47 | 17758 | 2588 |
DDX58,UNC93B1,PARP12,IL15,PARP14,TRIM5,TAP1,UBE2Z,HERC5,GPR180,SAMD9,CD274,HERC6,PGAP1,DTX3L,SP100,FAM46A,TRANK1,GRHL1,ZNRF2,IFIT1,OAS3,APOBEC3G,DDX59,PARP9,MX1,TGIF1,PLSCR1,PAPD7,USP18,ZSCAN12,AURKB,IFIT3,ZNF618,C19orf66,SEMA4D,TRIM69,SECTM1,STAT1,NLRC5,NR4A3,IRF7,CMPK2,SLC31A2,IFIH1,IFI6,IRF1 |
| 8.251e-05 | -9.40 | neuron part | cellular component | GO:0097458 | 1197 | 222 | 17570 | 2579 |
DOC2A,LAMP1,GRIK2,KLC2,EPHA4,RET,FBXO2,NDRG2,LGI3,LYNX1,HDAC6,DNER,TMC1,PICK1,GRM5,NCS1,SH3KBP1,PLS3,CALM2,CDKL5,IL6ST,CABP1,DPYSL2,DLG1,DNM2,MYH14,PPP1CA,CTTN,PACSIN1,MYRIP,CPE,ATL1,ORAI2,SGCE,SMARCA2,SOD1,PRKAR2B,SLC17A5,ARF4,IRX3,DPYSL3,PIAS3,TRIM9,GRID2IP,DNM1L,MAP2,KCNK1,PLK2,LIMK1,TMOD2,ITPKA,APBA2,NRGN,LZTS1,LMTK3,USH1C,SERPINE2,CALB2,STRN4,SLC25A27,CALM3,SLC1A3,CNTNAP2,APBA1,MERTK,DHRS3,ITGA3,CA2,IGF1R,SNX18,ZNRF2,RIMS3,OCRL,KCNN4,KIF13B,FLRT3,EXOC8,AHCY,NPTN,CNGA1,RIMS2,DPYSL5,CALM1,SHARPIN,SCRIB,VEZT,KIF20B,ELK1,CYFIP2,ILK,GNA11,NFIB,STX3,CDK5R1,PDE11A,FAS,RASGRP2,GNAS,PTPRF,IL1R1,TSC1,GABRD,HTT,PHLPP2,S100A5,AURKA,ARPC2,SHROOM2,SEMA3A,DRD1,TPRN,NF2,NQO1,SLC2A8,IQGAP1,P2RX7,KCTD12,BCL2L1,MICALL2,PRKACA,NOV,SRR,DAB2IP,GOT1,ESPN,ACSL4,SCN2A,DLG3,DOCK4,CLCN3,TIMP2,MBP,S100A4,DMTN,SEPT6,CCSAP,CLSTN1,SYP,ITPR3,TANC1,ALCAM,DAG1,GABARAPL1,PTGS2,ATP1A1,SLC9A6,WFS1,SIPA1L1,STAT1,NRG1,SPTBN5,RGS14,COBL,BIN1,ANXA3,PINK1,FARP1,SORT1,TAOK2,CPEB4,ENO2,BACE1,ARHGEF7,EPS8,LRP4,GABRG2,KCNC4,KIF5B,CAPN2,ANK1,ADD3,ADORA1,IGSF9,MLPH,GNB5,PTEN,CDK16,ANKS1B,KNDC1,MAGEE1,CST3,KLC3,ATP8B1,CPLX1,MAP3K7,RPGR,CAMK2G,MYO5A,HCN3,DLGAP1,P2RX4,MOB4,SYPL1,RASGRF1,ZWINT,RAB3B,RHOA,CASK,MPP1,RAPGEF2,GRIN1,VAMP3,STMN3,FXR2,FOS,MAPK8IP1,MAP1B,CNTNAP1,RGS9,LDLRAP1,PROM1,SYT7,CTSV,ARRB1,GRIN2D,GPER1,ACADM,CPEB2,L1CAM,ACOT7,SNPH,NGEF |
| 8.426e-05 | -9.38 | FCERI mediated MAPK activation | REACTOME pathways | R-HSA-2871796 | 248 | 60 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,DUSP5,FGF19,SPTB,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PLCG2,PAK2,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,SYK,RASGRP1,CAMK2G,PSMA5,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,FOS,PSMA4,EGFR,RASA1,IRS2,PLCG1,FYN,JAK1,PPP2R5A,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3,PPP2R5D,PSMC1 |
| 8.441e-05 | -9.38 | Antigen processing-Cross presentation | REACTOME pathways | R-HSA-1236975 | 81 | 26 | 8202 | 1235 |
MRC2,SEC61B,PSMB4,SEC61G,PSME2,HLA-E,HLA-F,TAP1,PSMD7,PSMD10,PDIA3,PSME1,PSMA4,HLA-A,CALR,CTSL,HLA-B,TAPBP,PSMD1,PSMD3,PSMC2,CTSV,ITGAV,HLA-C,PSMC1,PSMA5 |
| 8.684e-05 | -9.35 | regulation of phosphatase activity | biological process | GO:0010921 | 128 | 36 | 16441 | 2455 |
SPRED1,FARP1,LMTK3,PPP4R4,HSP90B1,PPP1R2,PPP1R12A,NUAK1,CALM3,TIPRL,SH2D4A,PPP2R3A,SYTL2,SH3RF2,CALM2,BMP2,NPNT,PPME1,CRY2,DLG3,SLC39A10,PPP6R1,CHP1,CAMSAP3,BAG4,CALM1,PKMYT1,GPLD1,TSC1,PPP2R5A,HTT,SEMA4D,PPP2R4,PPP2R2D,PPP2R5D,ARFGEF3 |
| 8.688e-05 | -9.35 | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | 171 | 44 | 17758 | 2588 |
DYRK3,TXN,IL15RA,ELOVL7,SOD2,IL18,CD274,CCNB1,SNX9,DUSP5,ICAM1,RND1,IER3,OTUD1,E2F7,PIK3AP1,FJX1,DRAM1,UBE2J1,SELK,RPGR,ATP2B1,LAMP3,DUSP1,B3GNT2,RIPK2,RAPGEF2,PLAUR,MGAM,PIM3,SAV1,CDK1,CD83,SOCS3,PTGS2,UAP1,ETS2,AREG,MFSD2A,NFKBIA,NFKBIZ,PLD1,GEM,MAFF |
| 8.698e-05 | -9.35 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | 126 | 35 | 17758 | 2588 |
HECA,TSC22D3,TMX4,ETNK1,GATA3,CCNL1,PHF1,MXD1,MGAT4A,ZFP36,FOSB,DUSP10,PDE4D,CNOT6L,MYLIP,TIPARP,B3GNT2,RNF11,PTGER4,TTC7A,SRSF5,DUSP4,KDM3A,TP53INP2,ZFAND5,STK17B,BCL10,IRS2,BTG1,AREG,NR4A3,NR4A2,TOB1,CBX4,ESYT2 |
| 8.728e-05 | -9.35 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | 202 | 50 | 17758 | 2588 |
FAM171B,LTBP1,SPRED1,LMCD1,GPR180,SLC1A3,PLXNA1,FAM198B,DNER,PHLDA1,TNFRSF19,SNX9,PPP2R3A,RPS6KA2,SRPX,ITGB8,VASN,ALDH1A3,FAM63A,ZNF365,FAM69A,GCNT1,SOAT1,QSOX1,C6orf1,NR3C1,RGMB,DENND1B,EIF5A2,AK4,LOXL2,GLT8D2,C3orf58,EGFR,IL1R1,SERTAD2,PLOD2,MAP2,MFSD2A,PEX2,MATN2,FIBCD1,INPP4B,TLE1,OSMR,NRG1,HMGA1,TANC2,MAFF,PKIA |
| 8.784e-05 | -9.34 | Signaling by ERBB4 | REACTOME pathways | R-HSA-1236394 | 312 | 72 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,CUL1,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,PSMD1,SHC3,PSMC2,PIK3CA,DUSP10,CDKN1B,DAB2IP,PIK3CD,RASGEF1A,RASGRP1,FRS3,AKT1,ITCH,CASP9,AGO4,DUSP4,IRS2,FYN,PPP2R5A,JAK1,PSMD3,MAP3K11,SPTBN5,NRG1,PSMC1,GAB1,PPP2R5D,TNRC6C,RASA2,PSMD7,CALM3,PSMD10,PHLPP1,FGF19,DUSP5,ITGA2B,PTEN,WWP1,ERBB3,NCAM1,CAMK2G,PSMA5,DUSP1,RASGRF1,ADAM17,PSMB4,NR4A1,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,RASA1,EGFR,FGFR2,PHLPP2,FGF18,ARRB1,GRIN2D,JAK3 |
| 8.794e-05 | -9.34 | LU_AGING_BRAIN_UP | MSigDB lists | LU_AGING_BRAIN_UP | 255 | 60 | 17758 | 2588 |
ANXA3,LTBP1,CAST,IQGAP1,ZCCHC24,NDRG1,LRP4,GNE,RGS20,COL4A5,PHLPP1,SEPT4,SEPP1,DHRS3,DDR1,EPM2A,ADD3,METTL7A,PAIP2B,FRYL,CALD1,BMP7,TAX1BP3,VAT1,ERBB3,TIPARP,HSPA2,CYP1B1,SEMA3B,LAMP2,AMOTL2,SYPL1,TGIF1,VAMP3,LITAF,YES1,MYL12A,DPYSL3,KDSR,MFAP3L,NT5C2,FYN,INSR,PDLIM3,SLC4A4,GPRC5B,WIPI1,PLOD2,FGFR2,WFS1,NFKBIA,WWTR1,LRIG1,MAOA,IRF7,ITGAV,MAP3K5,TOB1,NXT2,ABCG1 |
| 8.801e-05 | -9.34 | leading edge membrane | cellular component | GO:0031256 | 135 | 37 | 17570 | 2579 |
DDX58,PACSIN2,NF2,EPS8,GABRG2,CNTNAP2,NCKAP1,APC2,EPS8L2,VASP,ANK1,ADORA1,CDKL5,DNM2,PACSIN1,SPRY2,EPB41L5,SGCE,ADAM17,RHOA,SYNE2,SPATA13,GRIN1,EZR,AIF1L,ANTXR1,LCP1,ARF4,GABARAPL1,RASGRP2,PTPRJ,NRG1,GPER1,SPRY4,ITGAV,PIEZO1,ARHGEF4 |
| 8.809e-05 | -9.34 | KIM_MYC_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYC_AMPLIFICATION_TARGETS_DN | 88 | 27 | 17758 | 2588 |
DDX58,LAMP1,GCA,RAB3B,LCA5,TTC39B,GRHL2,LGALS8,ELOVL7,HMG20B,F11R,PIF1,NUCB2,DNER,SPAG1,OPTN,ELF3,DPYSL3,IL17RB,FAM111A,SCNN1A,CDH1,SHROOM3,KIF13B,PLEKHG1,KLF5,IFIH1 |
| 8.840e-05 | -9.33 | TAZ (tafazzin) | protein interactions | 6901 | 90 | 29 | 16036 | 2547 |
ADAMTS2,COL6A2,MFI2,GUSB,HAPLN3,CERCAM,PLAUR,HLA-F,GYLTL1B,CACNA2D2,COL18A1,LOXL2,GALNT7,PLXNA1,ARSK,SLC9A3R2,NRP2,CD109,ITGA7,XYLT2,GPC3,FRAS1,BMP7,MEGF8,GALNS,ITGAV,MOXD1,NAGA,TMEM131 |
| 8.858e-05 | -9.33 | cellular response to nitrogen compound | biological process | GO:1901699 | 660 | 134 | 16441 | 2455 |
SSH1,NRG2,PSME1,ITPR2,PDGFB,SPTB,CALM2,PSMD1,CTNNB1,SHC3,PSMC2,KLF3,PIK3CA,DNM2,AKR1B1,RASGRP1,SOD1,EZR,AGO4,PRKAR2B,PRKRA,POR,RHEB,ENPP1,NOD2,CAB39,EIF4EBP2,PSMC1,GAB1,RRAGD,PRKAA2,KLF2,RASA2,SOX9,PRKAA1,PSMD7,ATP6V1E2,CALM3,DUSP5,IGF1R,COL6A1,PRKCI,NCAM1,PSMA5,CALM1,STRADB,PSMA4,EGFR,RASA1,GNAS,TSC1,INSR,PRKAG2,SH3BP4,RAB31,NR4A2,MAP3K5,JAK3,COL16A1,TMEM173,DRD1,SPRED1,SLC2A4,SORBS1,PSME2,SLC2A8,WDTC1,ERBB2,P2RX7,RASGRP3,BCL2L1,PRKACA,GNB2,PDGFA,ATP6V0B,CDH1,RALB,GOT1,DAB2IP,IFIT1,PDE4D,RASGEF1A,FRS3,AKT1,RIPK2,DMTN,CASP4,SOCS3,IRS2,PTGS2,FYN,IDE,JAK1,PSMD3,STAT1,NRG1,SPTBN5,PRKAR1A,HSP90B1,CPEB4,TRAF2,FLOT1,PSMD10,GABRG2,FGF19,ICAM1,HDAC9,CAPN2,ERBB3,MYO5A,CAMK2G,HCN3,P2RX4,RASGRF1,PDGFC,SHMT1,ADAM17,WNT10B,PSMB4,NR4A1,RAPGEF2,PIK3R1,GRIN1,YES1,BCAR1,GPLD1,FGFR2,FGF18,NR4A3,GRIN2D,GPER1,ATP6V1C1,TBC1D4,CPEB2 |
| 8.858e-05 | -9.33 | thyroid-adenoma-nodule-goitre | COSMIC cancer mutations | thyroid-adenoma-nodule-goitre | 57 | 20 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,CCDC6,PIK3CA,SMO,TFG,JAK3,PRKAR1A |
| 8.867e-05 | -9.33 | MARSHALL_VIRAL_INFECTION_RESPONSE_DN | MSigDB lists | MARSHALL_VIRAL_INFECTION_RESPONSE_DN | 29 | 13 | 17758 | 2588 |
KLF2,TGIF1,PCNA,NFKBIA,KLF3,KIF23,SGK1,TCF7,PIM1,TOB1,RASGRP2,CKS2,TXK |
| 8.895e-05 | -9.33 | actin filament-based process | biological process | GO:0030029 | 439 | 95 | 16441 | 2455 |
SORBS1,NF2,SSH1,ADD1,TMSB15A,TRIP10,TESK2,F11R,MRAS,MICALL2,FAM101B,EMP2,TMSB15B,PDGFA,PAK6,ZYX,FRYL,DLG1,BCL6,ESPN,CTTN,MYH14,EPB41L4B,PACSIN1,NEB,DMTN,DSTN,SYNE2,EZR,ARHGDIB,LCP1,ABR,DPYSL3,PDLIM3,SHROOM3,PTK7,LIMK1,CORO1C,SIPA1L1,TRIOBP,PRKCDBP,TMOD2,SPTBN5,ARF6,ITPKA,COBL,FGD1,PRKAR1A,WASF3,INPPL1,TAOK2,HSP90B1,USH1C,PACSIN2,ARHGEF11,FRMD6,EPS8,SORBS3,RACGAP1,NCKAP1,SIX4,CORO1B,RND1,CALR,FLII,RAC2,VASP,PDCD10,FRY,LLGL2,PAK2,PRKG1,PRKCI,LIMCH1,MYO5A,FARP2,EPB41L5,SUN2,RHOA,FMN1,CORO2A,FBXO8,STRADB,DIAPH2,PLS1,ANTXR1,BCAR1,ABLIM2,SWAP70,RND3,ARAP1,FGD6,ARRB1,ARPC2,SHROOM2 |
| 8.968e-05 | -9.32 | ERBB2 (erb-b2 receptor tyrosine kinase 2) | protein interactions | 2064 | 144 | 41 | 16036 | 2547 |
HSP90B1,NF2,CD82,ERBB2,TEC,HDAC6,HLA-A,PICK1,ELF3,TNS3,IGF1R,CTNNB1,MUC4,ANKS1B,SHC3,IL6ST,DOK4,PLCG2,H2AFY,ERBB3,SYK,FRS3,PTPN18,SH3BGRL,PIK3R1,ERBB2IP,CBL,MAPK8IP1,RASA1,EGFR,TXK,BCAR3,NCOA3,PLCG1,JAK1,LRIG1,STAT1,OSMR,PIK3C2B,NRG1,TOB1 |
| 8.976e-05 | -9.32 | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | 197 | 49 | 17758 | 2588 |
TCF25,CPEB4,CAMKK1,CTSB,DGKA,ITPR2,MGST2,TRIB2,PHLDA1,TMPRSS4,EXT2,CARD10,SH3KBP1,KIAA1147,ARHGEF10L,EPCAM,DOPEY2,LLGL2,FICD,TPST1,KLC3,DAPK1,CDKN1B,CLDN4,STT3B,NOTCH3,MINPP1,PXMP4,DLG3,RAG1,GFI1,MBP,SLC37A1,RC3H2,MBNL3,CBL,KDM3A,CYB5A,SOCS3,PTPRF,TMEM50B,BTG1,PPP2R5A,ETS2,TJP3,AXL,ITPR1,EPB41L4A,TMEM131 |
| 9.026e-05 | -9.31 | MODULE_257 | MSigDB lists | MODULE_257 | 151 | 40 | 17758 | 2588 |
INPPL1,PACSIN2,TBC1D1,DNAJC3,PNPLA2,ARL4C,GABRG2,TGOLN2,TAF6L,SLC7A2,SLC20A1,EPS8L2,CHPF,GNS,APLP2,CA2,ADRBK1,MGAT1,PFKL,CALD1,PLK4,TNPO2,ECE1,CTSD,CAMSAP3,ELK3,AKT1,OXR1,CLSTN1,LITAF,HMG20B,SLC35C1,TCF7,TP53INP2,MMP15,ACAD10,LIMK1,SH3GLB2,PLXND1,EHD1 |
| 9.043e-05 | -9.31 | HOSHIDA_LIVER_CANCER_SUBCLASS_S3 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S3 | 266 | 62 | 17758 | 2588 |
PAPSS2,ALDH6A1,EPAS1,CRYM,CYP2J2,BLVRB,ASL,SOD2,COL18A1,IL13RA1,SLC7A2,MGST2,ITPR2,SEPP1,SDC1,EMP2,ECI1,SLC9A3R2,TGFBR3,CA2,BDH1,PLCG2,SORL1,TMBIM6,ALDH7A1,IFIT1,TINAGL1,ACOX2,CNGA1,ALDH3A2,FAH,CTH,EPHX1,SOAT1,PCCB,PGM1,SMARCA2,SOD1,SHMT1,ALDH2,AMFR,PIK3R1,ACO1,GGH,FXR2,CYFIP2,NFIB,EGFR,RHOB,CYB5A,INSR,ACADSB,ETS2,CGREF1,NFKBIA,MYLK,PGRMC1,MAOA,NRG1,ACADM,CD81,TOB1 |
| 9.050e-05 | -9.31 | peptidyl-amino acid modification | biological process | GO:0018193 | 929 | 180 | 16441 | 2455 |
TNK1,ACVR1,EPHA4,RET,NANS,MORF4L2,TAF6L,CCNB1,HDAC6,PDGFB,ASPHD2,WEE1,RPS6KA2,NUP210,P4HB,ASH2L,TFG,MGAT5,METAP2,PLK1,CDYL,ROR1,AURKB,SLC17A5,MCFD2,CDK1,POR,VCP,PIAS3,MAN2A2,MSL1,AREG,P4HA2,DOLPP1,PPP2R4,PRDM5,MAP3K11,MAPK13,TTC9,PRKAA2,DHPS,PRKAA1,RAB6A,TEC,B4GALT4,MERTK,CALR,IGF1R,PAK2,TPST1,MAP3K9,NPTN,STT3B,MAPK7,MAST4,NUP85,PPP6R1,TTLL1,TMED2,GFPT1,TESK1,MAPKAPK3,MGAT4B,WHSC1,EPHA1,PDK3,ILK,KDM3A,JADE2,ZDHHC3,EGFR,NMT2,CDK5R1,MAPKAPK2,NCOA3,INSR,UAP1,SETD3,CSNK1G1,TEX30,ZDHHC20,P4HA3,AGBL5,PIAS2,ZDHHC7,AURKA,STK39,CTSA,ALG2,CFAP20,IFIH1,JAK3,NUP58,EGLN1,RAD21,DMPK,IL15,P3H2,ERBB2,TESK2,PRKACA,DDR1,FLT3,SAP130,KMT5C,SETDB2,SP100,ZDHHC12,ZDHHC23,RPN2,EPHB4,EGLN3,LMAN1,F2R,CTH,SIRT1,PPIF,SEC23A,TAF5,RIPK2,AKT1,EPHA10,JADE1,FYN,DDOST,JAK1,AXL,PTK7,KIAA1804,B4GALT3,ST3GAL1,CBX4,MAPK12,CMAS,PINK1,DYRK3,TRAPPC10,MAN1A2,GNE,PDIA3,TGFBR1,CTSZ,PKN1,HDAC9,ZDHHC21,ADRBK1,CTSC,MGAT1,ALG13,MGAT4A,FUT8,UBE2J1,SGK3,SGK1,MAP3K7,SYK,SLC35A1,CRTAP,NCOA2,MLEC,RAB3B,EIF5A2,FURIN,COL7A1,YES1,TXK,CRTC2,GALNT3,FUCA1,SERPINA1,FGFR2,PRDX3,RYK,TADA2B,GLB1,CEP41,NUP37,HIPK3,MELK,PHC1 |
| 9.128e-05 | -9.30 | CORDENONSI_YAP_CONSERVED_SIGNATURE | MSigDB lists | CORDENONSI_YAP_CONSERVED_SIGNATURE | 57 | 20 | 17758 | 2588 |
HMMR,AMOTL2,NDRG1,CDC20,ETV5,HEXB,TNS1,GGH,EMP2,SH2D4A,TOP2A,CDKN2C,DDAH1,CTGF,CYR61,AXL,AGFG2,SGK1,MDFIC,DUSP1 |
| 9.171e-05 | -9.30 | PON2 (paraoxonase 2) | protein interactions | 5445 | 69 | 24 | 16036 | 2547 |
UGT8,B3GNT2,RHOA,ITGA6,CACNA2D2,FBXO6,ARSK,PGAP1,EGFR,M6PR,ENPP1,INSR,TMEM30A,IMPAD1,LRIG1,ABCA2,NETO2,NXPH4,LRP11,MOXD1,B4GALT3,POMGNT2,PPP2R5D,SULF2 |
| 9.199e-05 | -9.29 | SRC (SRC proto-oncogene, non-receptor tyrosine kinase) | protein interactions | 6714 | 326 | 78 | 16036 | 2547 |
SORBS1,TRIP10,THRA,IQGAP1,RET,EPHA4,TP53,DGKA,ERBB2,PRKACA,SH3KBP1,CD46,CTNNB1,CDH1,SH3BP1,DOK4,DNM2,CDKN1B,CTTN,PDE4D,TIAM1,PTPRE,THRB,PTPN18,AKT1,PTGER4,CBL,DAG1,EDNRA,ARHGAP35,PLCG1,FYN,MAP2,STAT6,SH2D3C,AXL,PPP2R4,MYLK,STAT1,CTNND1,EFNA5,DDX58,INPPL1,MPZL1,EPS8,CBLL1,PLD2,ETS1,EFNB1,SLC9A2,HLA-A,IGF1R,ADRBK1,PAK2,PRKCI,ADAM15,OSTF1,ERBB3,SYK,FARP2,RASGRF1,PLSCR1,NR3C1,PIK3R1,BCAR1,RASA1,EGFR,TXK,CNTNAP1,HLA-B,INSR,ETS2,NFKBIA,ARRB1,PLD1,AFAP1,CD33,EGLN1 |
| 9.216e-05 | -9.29 | GSE14308_TH2_VS_TH1_UP | MSigDB lists | GSE14308_TH2_VS_TH1_UP | 192 | 48 | 17758 | 2588 |
CD99,GCLM,SPRED1,TXN,TMEM86B,TRAF2,SOX9,ETV5,PBX3,CUL1,HMGN3,CENPN,CALR,IL6ST,PAPSS1,PRKCI,FAM63A,VAT1,CRTAP,RBMS2,ATP2B1,CAMSAP3,HES1,MLEC,CDC20,EIF5A2,CRIP2,PRRC1,ANLN,PRKRA,TP53INP2,FBXO10,BCAR3,FUCA1,HS6ST1,CARHSP1,WDR11,HNRNPH2,TMEM30A,RYK,TDRD7,GLB1,GRIN2D,MLKL,ARPC2,HOOK1,SRSF9,TMEM131 |
| 9.216e-05 | -9.29 | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN | 192 | 48 | 17758 | 2588 |
LMO7,TSC22D3,CTSB,TAP1,CYB561,CNTNAP2,FBXO6,ITPR2,BAIAP3,MGST2,TRIB2,DHRS3,DENND2D,CARD10,LGALS3BP,SLC25A35,DNAJB9,ARHGEF10L,CDKN2C,DOPEY2,STIM1,TPST1,KLC3,CLDN4,RAB20,RCAN3,DLG3,SCARA3,RASGRF1,ADCK3,PRKCQ,RAB3IP,KCTD2,CYB5A,LRRC42,ARHGAP24,ALDH3B1,CARHSP1,ETS2,TJP3,FAAH,P4HA2,SPINT2,CANT1,STK39,SH3BGRL2,EPB41L4A,ST3GAL1 |
| 9.216e-05 | -9.29 | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP | 192 | 48 | 17758 | 2588 |
RMND5A,KLF2,DYNLRB1,ADD1,DLGAP5,PEX6,DAP,DGKA,CDCA8,MGST2,MAP1LC3B,XPR1,PLS3,EPCAM,RAC2,OXCT1,PHTF1,CAPG,CD9,FXYD5,CDKN1B,IL17RA,MXD3,RNF26,CTSD,CTDSP2,IL1RAP,KDELR1,EPHX1,SUN2,QSOX1,KIF20A,SEPT6,PIK3R1,SPA17,SPATA13,TCF7,TNFAIP8L1,ARHGDIB,KIF11,TMEM50B,NUCB1,MPRIP,CASP7,PRKCDBP,CTSA,PLXND1,NRGN |
| 9.283e-05 | -9.28 | Glycosaminoglycan metabolism | REACTOME pathways | R-HSA-1630316 | 123 | 35 | 8202 | 1235 |
SLC35D2,PAPSS2,AGRN,HSPG2,SDC4,HEXB,DSE,B4GALT4,SDC1,EXT2,CHST2,CHPF,GNS,GPC3,PAPSS1,CHP1,B3GALT6,CHSY3,HMMR,B3GNT7,B3GNT2,GUSB,GLCE,HS6ST1,HPSE,SLC35B3,CSGALNACT1,GLB1,HS3ST3B1,B4GAT1,B4GALT3,ARSB,ST3GAL1,NDST3,HS6ST3 |
| 9.376e-05 | -9.27 | ER-Phagosome pathway | REACTOME pathways | R-HSA-1236974 | 64 | 22 | 8202 | 1235 |
SEC61B,PSMB4,SEC61G,PSME2,HLA-E,HLA-F,TAP1,PSMD7,PSMD10,PDIA3,PSME1,PSMA4,HLA-A,CALR,HLA-B,TAPBP,PSMD1,PSMD3,PSMC2,HLA-C,PSMC1,PSMA5 |
| 9.401e-05 | -9.27 | MAPT (microtubule associated protein tau) | protein interactions | 4137 | 99 | 31 | 16036 | 2547 |
SIRT1,CASP3,MARK1,AKT1,RPS6KA1,UBASH3B,CALM1,NUB1,PKN1,HDAC6,PRKACA,ARHGEF40,CDK1,SPTB,EGFR,CDK5R1,CAPN2,FYN,CASP7,PPP2R5A,PPP2R4,PSMC2,UBE2D2,SGK1,MAPK11,MAPK13,SYK,RPS6KA3,PRKAR1A,TUBA4A,MAPK12 |
| 9.433e-05 | -9.27 | Mitotic Anaphase | REACTOME pathways | R-HSA-68882 | 172 | 45 | 8202 | 1235 |
SPC25,PSME2,CENPI,PTTG1,NDC80,ERCC6L,CDCA8,PSMD7,PSMD10,NUF2,PSME1,KIF2C,SPDL1,CENPN,LMNA,CKAP5,PSMD1,PSMC2,BUB1,KNTC1,NUP85,PSMA5,PLK1,CENPA,ZWINT,PSMB4,CENPC,B9D2,CDC20,AURKB,SKA1,PSMA4,LEMD2,PPP2R5A,PSMD3,CDCA5,CENPE,NUP37,NDE1,SGOL1,UBE2C,PSMC1,ESPL1,PPP2R5D,RAD21 |
| 9.447e-05 | -9.27 | GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_DN | MSigDB lists | GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_DN | 187 | 47 | 17758 | 2588 |
RMND5A,ANXA3,SPC25,FOXM1,TAB3,BLVRB,GMPR,KIF23,CALM3,CCNL1,MAP1LC3B,CENPN,CALM2,C16orf59,ANK1,FBXO7,BCL6,SERINC2,PCGF5,CTNNAL1,IFITM3,MPP1,SAT1,CALM1,BNIP3L,STRADB,TNS1,CDK1,RANBP9,RHEB,TCN2,ARF4,KLHL2,FECH,HPSE,PVRL2,H1F0,CDCA5,E2F1,DYSF,ADIPOR1,YOD1,UBE2C,RAP1GAP,E2F8,ESPL1,MELK |
| 9.447e-05 | -9.27 | GSE7852_TREG_VS_TCONV_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_DN | 187 | 47 | 17758 | 2588 |
ANKRD13D,FAM160B1,DAP,ELOVL7,MCTP2,ARL4C,GABRG2,GRK6,DSE,FAM101B,SLC20A1,LBR,PGAP1,OTUD1,TGFBR3,SETDB2,CDH1,RINL,FBXL14,SGK1,FAM102A,IL17RA,CNGA1,ALS2CL,CTDSP2,PAQR7,ORAI2,PCCB,PLEKHO1,PRKCQ,NPC2,TANC1,KCTD2,PEX5,RTN4RL1,FAAH,RCBTB2,KBTBD2,PAPD5,ITPR1,APPL2,PPM1H,HS3ST3B1,WBSCR27,MAD2L1BP,CBX4,RNF146 |
| 9.447e-05 | -9.27 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | 187 | 47 | 17758 | 2588 |
LZTFL1,PNISR,FAM169A,HLA-E,TSC22D3,RASA2,PPFIBP2,BTN3A1,LTBP3,MARCH8,ACAP2,LLGL2,PAIP2B,LYPD3,KLF3,DLG1,FXYD5,KLF9,ECE1,MYLIP,TPCN1,CAMK2G,SMAGP,FAM134C,DUSP1,NAGPA,CD55,PAPD7,FOXJ2,ERBB2IP,ROR1,SRSF5,FOXL1,BSDC1,RASGRP2,TSC1,BTG1,ATP1A1,MSL1,RYK,FAM117A,TMEM8B,TTC9,TMEM159,TBC1D4,SNPH,FAM134B |
| 9.447e-05 | -9.27 | VEGF_A_UP.V1_DN | MSigDB lists | VEGF_A_UP.V1_DN | 187 | 47 | 17758 | 2588 |
RECQL,ST13,DLGAP5,UGP2,AASS,RASA2,NDC80,C5orf30,KIF23,TRAPPC8,SLC7A2,CCNB1,PGAP1,ATP13A3,PLK4,KIF22,BUB1,RGS5,OSTF1,RP2,KLF9,MAP3K7,PTPRE,RPGR,MYO5A,SMC4,CKS2,HMMR,CENPA,RAB3B,CTNNAL1,SAT1,ATP8B3,YES1,MEST,CBL,SPTLC2,KIF11,STEAP1,MAP1B,BCL10,NCOA3,UAP1,RND3,ACADM,CENPE,CCNB2 |
| 9.456e-05 | -9.27 | V$IK1_01 | MSigDB lists | V$IK1_01 | 261 | 61 | 17758 | 2588 |
ELK4,FAM89A,DOC2A,LTBP1,PACSIN2,ARAP3,IL13RA1,VARS2,SORBS3,APBA1,PRKACA,GNB2,CYP26A1,ICAM1,RND1,WWP2,IRF2BPL,CDKN2C,NAPG,ZNF687,RNF128,PPP1R10,SHC3,LHX6,ELF5,ZIC5,ABCA2,TFAP2A,TRPC1,VAT1,TWIST1,SEMA3G,NFKB2,CITED2,NCOA2,HCN3,NEK4,HN1L,TNIP1,TEF,VAMP3,ATP1B1,SAV1,MRPS36,PNKD,GNA11,SP4,ABR,COL12A1,ITPR1,NR4A3,FAM117A,SP6,HOXB13,KIF12,WDR62,ARPC2,STARD13,LIFR,NR3C2,COBL |
| 9.482e-05 | -9.26 | stomach-carcinoma-undifferentiated_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-undifferentiated_adenocarcinoma | 53 | 19 | 17775 | 2585 |
AKT1,ASXL1,RET,TP53,ERBB2,IDH1,FLT3,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,MSH2,JAK3,MSH6 |
| 9.482e-05 | -9.26 | undifferentiated_adenocarcinoma | COSMIC cancer mutations | undifferentiated_adenocarcinoma | 53 | 19 | 17775 | 2585 |
AKT1,ASXL1,RET,TP53,ERBB2,IDH1,FLT3,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,SMO,PIK3CA,MSH2,JAK3,MSH6 |
| 9.500e-05 | -9.26 | regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043122 | 229 | 56 | 16441 | 2455 |
PINK1,NLRX1,TRIM5,TRAF2,PSMD10,IL18,GSTP1,SLC20A1,TNFRSF19,IL18R1,NOV,CARD8,CTNNB1,IRAK1,BMP7,TSPAN6,ZDHHC13,SLC44A2,DAB2IP,TFG,MAP3K7,F2R,TRIM62,S100A13,EEF1D,CTH,MAP3K3,SIRT1,CXXC5,TRIM8,RHOA,RIPK2,TNIP1,S100A4,SHARPIN,LITAF,PRKCQ,CARD19,CD40,OPTN,BCL10,PTGS2,FYN,GPRC5B,PELI2,PLK2,SECTM1,NFKBIA,STAT1,NOD2,CANT1,TLE1,NDFIP1,F2RL1,TRAF5,HSPB1 |
| 9.517e-05 | -9.26 | renal system development | biological process | GO:0072001 | 271 | 64 | 16441 | 2455 |
LGR4,THRA,IQGAP1,RET,EPHA4,GATA3,OSR2,SDC1,PDGFB,TP73,EPCAM,CTNNB1,NPNT,DLG1,SMO,AKR1B1,TACSTD2,NOTCH3,TIPARP,SULF2,PYGO1,IRX3,WFS1,WWTR1,STAT1,OVOL1,PCSK5,NKX3-1,CDKN1C,ITGA6,SDC4,SOX9,LRP4,TGFBR1,SIX4,MECOM,SGPL1,BMP2,CTNNBIP1,ITGA3,CA2,FRAS1,GPC3,BMP7,BAX,TFAP2A,ACTA2,GCNT1,HES1,FMN1,AMER1,DCHS1,ILK,NPHP3,TSC1,PROM1,FAT4,FGFR2,TBX18,PKD2,GDF11,SOX8,OSR1,ADAMTS16 |
| 9.630e-05 | -9.25 | regulation of membrane lipid distribution | biological process | GO:0097035 | 36 | 15 | 16441 | 2455 |
PLSCR4,PLSCR1,KCNN4,ATP8A1,ATP9A,TMEM30A,ANO6,P2RX7,ATP8B1,ATP8B3,ANO9,ANO4,ABCA1,ATP10D,XKR8 |
| 9.663e-05 | -9.24 | CTTTGA_V$LEF1_Q2 | MSigDB lists | CTTTGA_V$LEF1_Q2 | 1147 | 212 | 17758 | 2588 |
TRIM2,RET,CACNA2D2,UBE2Z,MPP5,PLAC1,SEPT4,FAM101B,CARD10,CALM2,SUSD2,PHYHIP,RGS12,SESN3,ELMO2,NPNT,RGS3,SLC44A1,MITF,PHTF1,IL31RA,ELF5,KLF3,ANKFN1,STEAP2,DUSP10,TACSTD2,ZNF462,LAMP2,SMARCA2,PCGF5,CXXC5,SH3BGRL,CDYL,RNF11,BNIP3L,NFE2L1,MTRF1L,RNF19B,CDK1,ABR,TRIM9,ENPP1,TMEM164,NKD1,BMP1,CAB39,AGFG2,CTNND1,EIF4EBP2,TMEM8B,SPRY4,LEMD1,TTC39C,MAFF,RRAGD,HS6ST3,ALDH6A1,CHCHD7,ETV5,C6orf106,CALM3,DOCK11,TNFRSF19,IL18R1,TSPAN7,PSIP1,MECOM,TFAP4,AIM1L,RALGPS2,SNX18,OSTF1,PIM1,FAR2,CKAP4,GFPT1,ELK3,PCDH1,USP31,TBC1D8B,CALM1,DCHS1,TCF7,SRSF5,KDM3A,PCTP,STEAP1,PDE11A,XKRX,DGKH,MAGED2,SLC4A4,UAP1,H1F0,COL13A1,KBTBD2,MPP2,AGBL5,AURKA,SEMA3A,TOB1,LMO7,PLA2G4A,NCKAP5,PAX6,SORBS1,HOXB7,SUZ12,APOO,MORC4,COL18A1,RASGRP3,CD274,ZFYVE9,SYTL2,PDGFA,RCN1,ACAP2,KCTD15,ENPP5,BCL6,SMO,CDH3,DAB2IP,SCN3A,EBAG9,MBP,C6orf1,SLC39A8,SYNE2,PANK1,NUSAP1,GTF2A2,ASB13,ALCAM,CDC25C,SP4,FZD7,EBF2,NFIX,HSF4,CORO1C,OVOL1,TLE1,EFNA5,NRG1,PLXND1,AIFM3,LIFR,NDST3,ARNT,TTC8,OTUD5,ANXA3,CMAS,CTHRC1,DYRK3,TM2D2,TAB3,BACE1,DCAF7,HAL,CDCA3,GABRG2,PBX3,ETS1,HOXB2,FGF19,SIX4,NRP2,GBX2,NEO1,WWP2,C16orf74,FOXP2,ADD3,CEP97,ADRBK1,OXCT1,ANKS1B,CTSC,BMP7,FUT8,RRBP1,FAM63A,SGK3,ABCD1,TSPAN13,IQGAP3,PVRL4,TGIF1,CASK,WNT10B,PLSCR1,PIK3R1,UBE2A,RUNX3,LRRC1,AIF1L,PRDX4,PITX2,SCG2,AMMECR1,FGF18,NR4A3,PPP2R3C,FOXA1,GOLGB1,RGMA,TLL2,PHC1 |
| 9.665e-05 | -9.24 | GSE3982_EOSINOPHIL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_BASOPHIL_DN | 182 | 46 | 17758 | 2588 |
DDX58,CMAS,ZNF395,EPAS1,TUBB4B,NDRG1,ERI2,C6orf106,INTS8,PLA2G16,COX6C,SSX2IP,ZFYVE16,PSMD1,ADD3,TAF1B,FUT8,TPST1,SRP54,RPN2,APIP,PIKFYVE,TRAM1,SMC4,UPF3A,PDGFC,ING1,FBLN5,CASK,MMD,CLSTN1,COX11,PRKCQ,ESYT1,SPTLC2,SGPP1,OPTN,DNAJC10,PPP2R5A,JAK1,WDR11,STK38,IARS2,PKD2,STK39,LTA4H |
| 9.676e-05 | -9.24 | TBK1.DF_DN | MSigDB lists | TBK1.DF_DN | 272 | 63 | 17758 | 2588 |
EXPH5,CCNE2,PNISR,SERPINE2,ZNF395,GNPDA1,DNAJC3,SLC25A13,GNE,ETNK1,COL4A5,BCL2L1,KTN1,CCND1,PDGFA,ACAP2,KIF14,OSBPL3,FLRT3,LMO4,BDH1,MSH2,PCYOX1,IRF2,IFIT1,SPRY2,KCTD3,MPHOSPH9,ATP2B1,TBC1D10B,SMARCA2,MBP,MRPS33,ZWINT,SLC39A8,DENND1B,SNTB2,ITCH,CBX6,GALNT7,DNAJB14,YES1,PRKRA,FOS,PDHX,DCP2,GALNT3,NCOA3,AP1AR,CDCA4,IDE,PAFAH1B3,DCK,AMMECR1,MAOA,ERAP1,KLF5,ATP6V1C1,CBX5,HOOK1,HIPK3,PTGES,KLF7 |
| 9.680e-05 | -9.24 | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | 7269 | 1144 | 17775 | 2585 |
IBTK,GRIK2,AK7,PNPLA2,RET,MCOLN3,BAIAP3,LACTB2,SNX9,CARD10,LTBP3,GRM5,CDKN2C,PHYHIP,ATP13A3,DNM2,PPP1CA,TMEM37,TIAM1,IL10RB,TIPARP,MGAT5,DNAAF3,TFAP2C,PRKAR2B,ABR,ARF4,LCP1,PIAS3,ENPP1,PLCG1,CARHSP1,MPRIP,ATP7B,FAM114A1,NOD2,RNASEL,ANXA11,SCN5A,GGA1,ITGA6,MTL5,FAM21C,TTYH3,RABGGTA,TFAP4,RAC2,FRY,MEGF8,RIMS3,FLRT3,FBXO7,FBXL14,MAP3K9,USP1,ALPK1,FAM84B,PANX2,MAPK7,ZMYM1,DGKG,ULBP2,NUP85,PAQR7,HPS3,ELK1,NPHP3,GOLT1A,DPYSL4,SFXN5,GNA11,SLC4A4,ETS2,DGAT2,CLMN,OSCP1,TMEM173,DOCK9,WDR63,TPRN,LFNG,GRK6,FAM91A1,MOCS1,REPS1,RCN1,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,LRP11,ETV4,MYT1,COL6A2,PFKFB2,HTATIP2,DNAJB14,XRCC6BP1,TANC1,TRIM7,EBF2,GIGYF1,NFIX,CCNB3,SHROOM3,CORO1C,PNPLA6,FAM149A,DMWD,ISOC1,FAM189A2,HABP4,OSGIN2,BTN3A1,ZNF219,NFAT5,DIRAS3,SLC25A45,IGSF9,KNDC1,TMEM62,CST3,IGFBP2,RAG1,PARP9,PVRL4,PIK3R1,NUB1,PGBD1,CNTNAP1,PROM1,LDLRAP1,PLOD2,SYT7,ITGAV,CMPK2,ACOT7,SRSF9,TNK1,BCAM,KIAA1462,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,TEX2,GALM,MGAT5B,ITPR2,SPTB,FANCI,SUSD2,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,P4HB,IL6ST,SLC44A1,MITF,ABCA2,NTN4,PLK1,MARK1,KCNIP3,CELSR2,CR2,CCBL2,CKAP2L,NKAIN1,KDM4D,TRIM9,TNS4,KCNMB4,KLF11,TC2N,HS6ST3,PRSS8,RUNX2,USH1C,HJURP,SORBS3,NCKAP1,RSAD1,TNS3,FRAS1,ICAM5,FCHO1,FAR2,WNT3A,DPYSL5,PCDH1,PLEKHA6,RGMB,MGAT4B,SCRIB,PDK3,CDK5R1,PRX,NMT2,RASGRP2,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,SEMA3A,CDAN1,CCNB2,USP43,RAD21,HOXB7,TP53,P2RX7,EMP2,STIL,TTC21B,WDR44,TACC2,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,CTDSP2,SULF2,AKT1,PTGER4,DAG1,ATP13A2,PTGS2,ZNF628,IDE,RBL1,STK38,IRF7,ARHGAP4,ST3GAL1,CTDSP1,CMAS,CDH22,CPEB4,SCD5,GNAL,MCTP2,HAL,CDCA8,ERCC6L,IL22RA1,PARM1,NRP2,SH2D4A,CD109,GTF2F2,FAM63A,IL17RA,TRIM21,HMGCL,SYK,FAM134C,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,PRICKLE1,DPP9,MAML2,GGH,COL7A1,RNPEP,TXNDC11,USP6,CNOT2,SCG2,NEIL3,E2F1,ICOSLG,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,FAM171B,LAMP1,LGR4,HSPG2,CUL1,CAMK1D,SEPT4,VASH1,PJA2,PICK1,CYP1A1,ANKS6,ZNF823,STIM1,POLL,PIK3CA,HYLS1,METAP2,SGCE,SPATA18,ACVR1C,CDYL,KIF13A,LDB2,PPP2R4,LRIG1,NFKBIZ,F2RL1,SLC31A2,FGD1,SEMA6B,RECQL,MRC2,TBC1D1,AKAP17A,PDXDC1,SH3RF2,CALR,DOPEY2,RALGPS2,LYPD3,BHLHE41,AIM1,DAPK1,PRKG1,ADCK2,TPST1,CACNA1D,C8orf58,TRAK2,SPATA20,PIGC,GCC2,KCNJ12,ADCK3,LPGAT1,DCHS1,PYGL,WHSC1,NPC2,ATP8B3,ANTXR1,PDE11A,MMP15,SLCO4A1,PLEKHH2,TJP3,MATN2,MPP2,APPL2,ARAP1,CABIN1,CDK18,PER3,PLIN3,HOOK1,IFIH1,EHD1,SPRED1,TCF25,GPR107,CAPN12,ST14,CCDC110,RALBP1,DDIT4L,ATP2C2,BCL2L1,FLT3,DDR1,CYP39A1,ZFYVE9,EPS8L2,C11orf84,CCNA2,ACAP2,TRANK1,EPHB4,OSBPL7,NAGA,ATG4D,DOCK4,FOXJ2,CLSTN1,UTRN,KIF1C,PKMYT1,CBL,ITPR3,FZD7,ACAD10,NGFRAP1,TRIOBP,SLC27A3,MAMDC2,DEPDC1,SLC41A1,EPS8,PBX3,PLD2,DNAH3,COX7A2,HLA-A,CKAP5,SLC25A36,WWP2,RASSF8,E2F7,FUT8,DRAM1,ERBB3,SLC16A5,MSH6,FARP2,TGIF1,PDGFC,ALDH2,LONRF3,ZC3H11A,PAPD7,ZKSCAN2,DIAPH2,FOS,CDK5RAP1,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ABCB1,WDR91,WDR62,ESPL1,MELK,RGMA,UBE2Q1,VARS2,PLAC1,ADPRHL1,ZFYVE16,SIPA1L2,HSF2,CDKL5,CASC4,ARHGEF37,ANKFN1,TRPC1,CTTN,MYRIP,IL1RAP,NLRP4,CXXC5,ASXL1,LAP3,USP18,RGAG1,MAN2A2,GPRC5B,MADD,TDRD7,RBM43,NR2C2,PCSK5,ARAP3,ZNF395,SERPINE2,PYROXD2,ETV5,FAM81A,ADAMTSL4,QSOX2,DUSP5,B3GALNT1,NOXA1,OCRL,COL6A1,MTMR10,PRKCI,LIMCH1,NPTN,HLA-C,ETV7,SLC12A2,SNED1,ELK3,PODXL2,VWA1,PDE5A,KIAA1109,HEATR5A,PDIK1L,C3orf58,STEAP1,MFSD7,RHPN1,SOX13,UAP1,NXPH4,CTSA,SHROOM2,JAK3,TOB1,COL16A1,RARG,SNX30,DRD1,CCNE2,LMO7,NCKAP5,LZTFL1,SORBS1,COL18A1,OSR2,EXT2,SAP130,ZNF687,CYP4F11,ZBTB49,EPB41L4B,ETHE1,NFKB2,SOAT1,C3orf52,GLO1,TMTC2,CASP4,ARHGAP35,SPTBN5,ABCA1,FBLIM1,TSPAN15,ARHGEF7,SHPRH,COL4A5,SBF1,XPR1,ITGA2B,HDAC9,TMEM63A,TOP2A,CARD8,A4GALT,BMP7,RRBP1,ARVCF,KANK2,CLIP2,RPGR,MYO5A,PGM1,PHF20L1,DCAF6,RC3H2,TTC7A,FAM73B,ENDOD1,CASP7,FIBCD1,RAP2C,CSGALNACT1,DTX4,ARRB1,PLOD3,NGEF,DOC2A,ACACB,KLK10,TRIM24,IL15RA,TRIM5,MRPS15,AASS,DNAJC3,CACNA2D2,SMARCAL1,NRG2,DHX8,LGI3,CNTROB,KIF26A,BARD1,PHF1,EPDR1,ZYX,TGFBR3,RGS12,ARHGAP42,PSMD1,DNAH6,RDH14,SEMA3G,MANF,ERAP2,TUBA4A,NWD1,SMARCA2,SPEF2,SPRTN,LOXL2,MYOM1,COL12A1,SLC44A3,TRIM47,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,AGFG2,SERPINB6,E2F8,GAB1,ALDH6A1,TMTC3,CYP2J2,SOX9,STRN4,SLC36A4,ZNRF3,MERTK,RAVER2,DNPEP,WDFY1,CD22,PRICKLE4,ZIC5,NCAM1,EPHX1,UFD1L,KIF20A,STAT4,MYBL2,PLS1,SPTLC2,PTPRF,NCOA3,SCARB2,MTFMT,SEMA4D,HTT,ITPR1,DYSF,OSMR,NDE1,ZNF502,XDH,ARHGAP11A,MTM1,PAPSS2,GALNT12,ACTR8,FAM131C,RGS20,TESK2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,UHRF1BP1L,CDS1,SCNN1A,RNF220,SP100,DACT1,RTKN2,ACSL4,TMEM9,SCN3A,ENPP4,SSH3,CAMSAP3,PLEKHO1,SYNE2,RAB38,TTC12,SLC9A6,SIPA1L1,PLEKHG1,PDXK,RGS14,GEN1,TTC8,TNRC6C,RBM24,PARP14,PKN1,NUCB2,ETS1,SRPX2,ICAM1,PDIA4,DTX3L,CAPN2,CXCL16,ANK1,SLC27A6,IRAK1,FAM160A2,ANKS1B,KCNK5,PLEKHF1,TMBIM6,TPCN1,CRTAP,HCN3,AMOTL2,FAM160A1,RAPGEF2,EIF5A2,GRIN1,PLEKHA7,EMP3,SNTB1,ABLIM2,GALNT3,KIAA0141,ACVRL1,ATXN7L3,FHL1,CYBRD1,DCBLD1,PPM1J,CUL4B,FHDC1,SUDS3,MCCC1,HDAC6,PDGFB,PCNA,LMAN2L,MKRN3,DDHD2,RGS5,TLN2,PXMP4,ANO4,NEB,DDX59,ZNF462,CD55,HN1L,ANLN,IDH1,ZBTB7B,LHFPL2,CLCN2,VCP,OPTN,DPYSL3,PLCH1,MFAP3L,TBC1D17,WIPI1,MAP2,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,POMT1,EPB41L4A,GLCCI1,FAM89A,PRKAA2,HLA-F,CNTNAP2,DOCK11,PGAP1,IL18R1,SSX2IP,RB1,DAZAP1,IGF1R,SPIN4,PLCB2,ALDH3A2,PSMA5,C9orf9,ABCC1,CHSY3,WDR72,TESK1,PCBP3,SPATA13,EIF2AK1,ANKRD29,ZDHHC3,G2E3,MAPKAPK2,EPN3,H1F0,MFSD2A,ITGA7,LTBP2,AVPI1,NF2,XYLT1,ZNF28,ERBB2,CCDC68,FAM198B,LPIN3,CYP26A1,SDF4,PER2,SRPX,PLCG2,LHX6,SRR,GYS1,SCN2A,DVL2,GM2A,CTH,SIRT1,MBP,FIGNL1,DUOX1,DNAJC10,ATP1A1,PTK7,ADAMTS14,ZBTB6,NDST3,ZNF701,GSDMD,MAN2B2,COL9A3,PACSIN2,MACC1,RUSC2,GNE,DSE,CRABP2,SIRPA,SLC9A2,PPP2R3A,FAIM,CAMK2G,IGDCC4,DLGAP1,NR3C1,AMFR,PPARA,CAPNS1,BCAR1,PRDX4,CD83,FAT4,SERPINA1,TWSG1,TMC5,NMI,NETO2,PGRMC1,FAM117A,PKD2,UBE2C,TBC1D4,SAT2,SUN1,GAA,PPP4R4,FAM129B,ATP8A1,PPFIBP2,PLXNA1,FAM101B,SLC20A1,ELMOD2,ZFP36,IQCE,PRICKLE3,RGS3,AOX1,ATRNL1,IQCD,SMYD5,HSPA12A,NBPF3,MGAM,TNS1,GALNT7,CCNF,MCFD2,ULK2,ARHGEF26,AHRR,RBM47,GNPTAB,PTER,NKD1,FAM110C,UNC5B,TANC2,RTN3,DLAT,MRPL44,HLA-E,SLC25A27,KIF23,NOTCH2,ISYNA1,KIAA1161,MECOM,SNX18,PIK3AP1,CTPS1,RUNDC3B,SORL1,CTSD,EEF1D,RIMS2,IGSF3,EPB41L5,QSOX1,FADS2,B3GNT7,PMPCB,MFI2,TBC1D8B,AMER1,ANO6,PTPRH,PIP4K2C,FAM133B,PKM,KDM3A,GLT8D2,FBXO10,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,NAB2,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,PKD1L2,NLRX1,SUZ12,IQGAP1,EGR3,MNS1,APLP2,CYHR1,ZNF75D,FAM46A,FICD,TNPO2,PHKA2,LGMN,TBC1D10B,MYO5B,SEC23A,CAPN6,TEP1,SLC11A2,C15orf39,AKR1E2,SP4,ZNF469,NIN,PRDM11,OSBPL2,EPHA10,JAK1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,NR3C2,DENND5B,PCOLCE,ANKRD13D,SLC16A14,ATP9A,CCNJL,GPR180,SIX4,LGALS3BP,MGAT1,PTEN,SLC44A2,TAGLN2,CNOT6L,MAP3K7,GFI1,TRIM62,OSGIN1,SMC4,RASGRF1,PCCB,ARAP2,CASK,DENND1B,FURIN,PARP4,RGS9,MAMDC4,CTNS,PGM2L1,GRIN2D,ARSB,OCLN,USP16,JARID2,ESYT2,LTBP1,TMEM184B,CPT2,HEBP1,EPHX4,KIF2C,TAF6L,KREMEN1,TMC1,ABCD4,CHPF,ARHGEF10L,LRRC6,ANKRD12,KIF22,MYH14,ARNT2,RASGRP1,OLFML2A,TDP1,TRIM8,SYNE3,FOPNL,ROR1,PTGFRN,TCN2,SEC14L2,LRRC42,CXXC4,ARHGEF19,UEVLD,TRIM45,IARS2,ADIPOR1,MIIP,PSMC1,GRN,LRRFIP2,ASL,ATP6V1E2,SAMD9,PHLPP1,ZNF432,KCNN4,FNIP1,FXYD5,RFX5,KNTC1,PARD3B,OXR1,GYLTL1B,FBXO8,EGFR,MUM1L1,GLCE,GNAS,FECH,BCAR3,TSC1,PAPD5,CDCA5,ALPK3,KLF7,FBXW5,PROM2,GAS2L1,SLC25A24,ZSWIM5,MORC4,TDRKH,PATL2,MICALL2,SLC25A48,KCTD15,SETDB2,FRYL,ZDHHC12,SMO,STEAP3,HSPA2,SCYL3,MAP3K3,KREMEN2,SLC39A8,OSTM1,ERBB2IP,DUSP4,BFSP1,BHLHB9,OVOL1,CANT1,CYP2U1,PLXND1,AKNA,PPP2R2D,CBX4,FRMD6,LRP4,TRMT2B,POMGNT1,SNX13,MLPH,GALNS,KIAA0319,BRD7,IQGAP3,ASPM,NR4A1,LRRC66,OGDHL,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,SOX8,L1CAM |
| 9.714e-05 | -9.24 | heart development | biological process | GO:0007507 | 440 | 95 | 16441 | 2455 |
CASP3,GAA,ACVR1,TCF25,GRHL2,HSPG2,IRX4,GATA3,PKP2,ERBB2,CCNB1,STIL,PDGFB,PCNA,TGFBR3,RPS6KA2,SETDB2,CTNNB1,LMO4,SMO,GYS1,TWIST1,ECE1,EPHB4,CPE,DVL2,ASXL1,SAV1,EDNRA,PTPRJ,PDLIM3,TBX1,TRAF3IP1,NRG1,PLXND1,GAB1,PRKAR1A,PCSK5,SCN5A,NKX3-1,BVES,CCM2,SOX9,TGFBR1,NCKAP1,NOTCH2,DHRS3,FGF19,LMNA,HDAC9,MECOM,BMP2,CALR,ITGA3,ADRBK1,OXCT1,PTEN,CYR61,GATA2,GPC3,MEGF8,FLRT3,ADAM15,ERBB3,CITED2,WNT3A,SGCB,POU6F1,HES1,SALL4,DCHS1,PPARA,FHL2,CALCRL,WHSC1,ILK,NPHP3,FOXL1,C3orf58,GNA11,LEMD2,PITX2,MOSPD3,TSC1,INSR,FAT4,FGFR2,TBX18,ALPK3,PKD2,EFNA1,ZMIZ1,OSR1,SHOX2,EGLN1 |
| 9.868e-05 | -9.22 | SHEPARD_CRUSH_AND_BURN_MUTANT_DN | MSigDB lists | SHEPARD_CRUSH_AND_BURN_MUTANT_DN | 177 | 45 | 17758 | 2588 |
TNRC6C,DLGAP5,FOXM1,CKAP2,CDCA3,KIF23,RACGAP1,HMGN3,KIF2C,NOTCH2,CCNB1,PTEN,KIF14,FAM13B,PRC1,PLK4,SLC44A2,PLEKHF1,SLAIN2,ARNT2,LGMN,RASGEF1A,CKS2,PHF20L1,ASPM,CDC20,CDCA2,AURKB,PIF1,ANLN,BORA,KIF11,KDM3A,CDK1,DPYSL3,MDK,ATP1A1,CCNB3,NEIL3,HMGA1,NDE1,FZD5,CCNB2,MELK,GOLGB1 |
| 9.868e-05 | -9.22 | CARBOHYDRATE_METABOLIC_PROCESS | MSigDB lists | CARBOHYDRATE_METABOLIC_PROCESS | 177 | 45 | 17758 | 2588 |
GAA,GALK1,SLC2A4,UGP2,GNPDA1,SLC2A8,GNE,XYLT1,EXT2,CHST2,EPM2A,B4GALNT1,GNS,FUT2,MGAT1,PTEN,PFKL,FUT8,FUT1,AKR1B1,PHKA2,GAD1,SLC35A1,GFPT1,B3GALT6,NAGPA,ALDH2,GUSB,COG2,ACO1,MGAM,GALNT7,PDK3,IDH1,GLCE,IRS2,DHDH,HS6ST1,INSR,HPSE,UAP1,CSGALNACT1,HS3ST3B1,GLA,POMT1 |
| 9.868e-05 | -9.22 | RPS14_DN.V1_DN | MSigDB lists | RPS14_DN.V1_DN | 177 | 45 | 17758 | 2588 |
ARHGAP11A,PCOLCE,DYRK3,IL15RA,DEPDC1,DLGAP5,REPS2,LGR4,CDCA3,ERCC6L,KIF23,KIF2C,ISOC2,EMP2,SPTB,EPCAM,B3GALNT1,FICD,PRC1,SRR,MSH2,TUBG1,STEAP3,RGS5,KANK2,ERCC2,TLN2,MYLIP,PLK1,SHMT1,HMGN5,KIF20A,PBK,CDC20,MYBL2,KCTD20,AGFG2,CENPE,FZD5,RAP1GAP,CCNB2,ESPL1,E2F8,CYBRD1,DOCK9 |
| 9.955e-05 | -9.21 | DOANE_BREAST_CANCER_CLASSES_DN | MSigDB lists | DOANE_BREAST_CANCER_CLASSES_DN | 33 | 14 | 17758 | 2588 |
SPP1,TIMP2,ARTN,POPDC3,PLOD2,PLAUR,LMO4,WWTR1,PAPSS1,SMO,SERPINB5,CLIP4,PYGL,SGCB |
| 1.000e-04 | -9.21 | E-cadherin signaling in keratinocytes | Pathway Interaction DB | ecadherin_keratinocyte_pathway | 19 | 12 | 2227 | 480 |
PLCG1,ZYX,RHOA,FYN,VASP,AKT1,CDH1,FMN1,PIK3R1,PIK3CA,CTNND1,EGFR |
| 1.002e-04 | -9.21 | MODULE_44 | MSigDB lists | MODULE_44 | 316 | 71 | 17758 | 2588 |
HSPG2,S100A11,TSC22D3,INPP5D,TAP1,DGKA,GMPR,IL27RA,SDC1,ZYX,TYMP,SRPX,SP100,TRANK1,CDH1,SH3BP1,LMO4,CAPG,BCL6,DNM2,TACSTD2,IFIT1,LGMN,CPE,CYP1B1,LAMP3,MX1,VPS11,COL6A2,PFKFB2,S100A4,SEPT6,ARHGDIB,CASP4,LCP1,ENPP1,JAK1,STAT1,MAOA,PLXND1,ARHGAP4,GRN,ITGA6,ASAH1,SELL,TRIB2,NUCB2,SEPP1,ETS1,DHRS3,TSPAN7,M6PR,RAC2,SPP1,CTSC,CD22,COL6A1,IGFBP2,TMX1,PLSCR1,PIK3R1,EMP3,TCF7,IFIT3,EGFR,IL1R1,FUCA1,CD8A,ITPR1,RAB31,OCLN |
| 1.006e-04 | -9.20 | apical junction complex | cellular component | GO:0043296 | 126 | 35 | 17570 | 2579 |
DDX58,SORBS1,FRMD4A,BVES,FRMD6,TGFBR1,F11R,MPP5,MICALL2,CCND1,EPCAM,VASP,CDH1,CTNNB1,TBCD,PRKCI,DLG1,CLDN4,POF1B,EPB41L4B,DLG3,AMOTL2,CAMSAP3,RHOA,CRB3,RAPGEF2,PARD3B,PLEKHA7,TJP3,PVRL2,SHROOM3,RAP2C,FZD5,SHROOM2,OCLN |
| 1.007e-04 | -9.20 | Tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)) | protein interactions | 24812 | 5 | 5 | 16036 | 2547 |
PDIA3,CALR,HLA-B,TAPBP,HLA-A |
| 1.014e-04 | -9.20 | GAGCCTG,MIR-484 | MSigDB lists | GAGCCTG,MIR-484 | 98 | 29 | 17758 | 2588 |
HSPG2,PTGER4,NFE2L1,WHSC1,SNN,CBL,DAG1,TYSND1,COL12A1,M6PR,MAPKAPK2,PTPRF,CRTC2,PLEKHH2,KLF12,HTT,DPYSL2,DOLPP1,ZIC5,MAP3K11,TRIOBP,PCDH19,PITPNA,NFKBIZ,SP6,CEP41,SCARA3,PTPRE,FAM134B |
| 1.019e-04 | -9.19 | apical part of cell | cellular component | GO:0045177 | 347 | 77 | 17570 | 2579 |
ACVR1,NF2,ERBB2,SYTL4,VASH1,EMP2,SLC9A3R2,EPCAM,SVBP,SCNN1A,CTNNB1,SLC46A1,SRR,TUBG1,CLDN4,EPB41L4B,PDE4D,LGMN,RAB27B,MYRIP,FLOT2,GM2A,DVL2,MYO5B,EZR,MGAM,SLC11A2,ATP1B1,ITPR3,DUOX1,ATP1A1,SHROOM3,STK26,KCNK1,SPTBN5,NRG1,MYL12B,LZTS1,USH1C,CTSB,PRKAA1,SLC25A27,FLOT1,GPSM2,ANO1,FZD6,SPP1,CA2,PTEN,KCNN4,CD9,PRKCI,ATP8B1,IGFBP2,ERBB3,SLC12A2,P2RX4,AMOTL2,ADAM17,CRB3,RAPGEF2,DCHS1,VAMP3,STX3,PROM1,FAT4,TJP3,TMEM30A,CTSV,OSMR,STK39,PLD1,MAL2,ATP6V1C1,SHROOM2,OCLN,PROM2 |
| 1.029e-04 | -9.18 | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN | MSigDB lists | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN | 49 | 18 | 17758 | 2588 |
SMARCA2,ZNF395,AASS,CASP9,FOS,SESN1,ARHGEF40,LTBP3,MARCH8,TBC1D17,FRY,KIF13B,WDR19,DIXDC1,CRY2,STARD13,CYBRD1,CTDSP1 |
| 1.029e-04 | -9.18 | positive regulation of cellular component organization | biological process | GO:0051130 | 1056 | 201 | 16441 | 2455 |
AGRN,ATP8A1,EPHA4,RET,CAMK1D,CCNB1,HDAC6,SNX9,PDGFB,SDC1,PHF1,PICK1,NPM2,CTNNB1,CTGF,CDKL5,SIVA1,PSMC2,DDHD2,MITF,DLG1,CAPG,DNM2,CTTN,PACSIN1,TIAM1,PLK1,VPS11,DSTN,NBPF3,EZR,AURKB,VCP,LCP1,ABR,DPYSL3,GPRC5B,DNM1L,LIMK1,NOD2,PIEZO1,ITPKA,ARF6,RAP1GAP,F2RL1,PSMC1,GRN,BMF,SERPINE2,SOX9,SORBS3,NCKAP1,MERTK,CORO1B,BMP2,CALR,RB1,RAC2,VASP,ITGA3,IGF1R,GATA2,MEGF8,FLRT3,NEK2,PRKCI,FNIP1,SLAIN2,TNFRSF12A,NPTN,NTN1,WNT3A,RIMS2,EPB41L5,MFI2,ANO6,PIP4K2C,PLS1,EPHA1,ILK,STX3,CDK5R1,FAS,TSC1,INSR,HTT,SEMA4D,TMEM30A,CDCA5,ARAP1,AURKA,OSCP1,ARPC2,COL16A1,CTBP1,EHD1,PROM2,FOXO6,SORBS1,NF2,DLGAP5,TP53,ERBB2,P2RX7,MICALL2,MNS1,ARHGEF16,EPS8L2,RALB,PLCG2,BCL6,PLK4,CDKN1B,DAB2IP,TWIST1,ESPN,TSPAN1,LMAN1,CHP1,SIRT1,PPIF,PSRC1,BAG4,AKT1,DMTN,CDC20,VPS4B,CLSTN1,PRKCQ,NUSAP1,CBL,DAG1,ARHGAP35,FYN,IDE,PTPRJ,BHLHB9,AXL,PTK7,CORO1C,WWTR1,TRIOBP,NRG1,EFNA5,COBL,TCAF1,PINK1,CD63,ARHGEF7,SDC4,LRP4,BIK,FLOT1,CBLL1,NES,TGFBR1,GDF15,CRABP2,SRPX2,ICAM1,ADGRB2,KIF5B,ANK1,PTEN,BMP7,GPC3,FAM20B,TUBGCP6,GTF2F2,BAX,BRD7,CNOT6L,SYK,FAM134C,HES1,RHOA,WNT10B,FMN1,RAPGEF2,PLAUR,PIK3R1,EIF5A2,RGCC,MPV17L2,MAP1B,CNOT2,LDLRAP1,SWAP70,TADA2B,E2F1,ARRB1,ITGAV,GPER1,FZD5,ARSB,SHOX2,UBE2C,ESPL1,AHR,L1CAM,JARID2 |
| 1.034e-04 | -9.18 | MAPK1/MAPK3 signaling | REACTOME pathways | R-HSA-5684996 | 234 | 57 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,IL6ST,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,CDK1,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.041e-04 | -9.17 | cellular response to insulin stimulus | biological process | GO:0032869 | 358 | 80 | 16441 | 2455 |
SPRED1,SORBS1,SLC2A4,SLC2A8,PSME2,WDTC1,NRG2,ERBB2,RASGRP3,PSME1,PDGFB,SPTB,CALM2,PDGFA,ATP6V0B,PSMD1,SHC3,PSMC2,PIK3CA,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,AKT1,RHEB,IRS2,ENPP1,FYN,IDE,JAK1,PSMD3,CAB39,EIF4EBP2,SPTBN5,NRG1,PSMC1,GAB1,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,ATP6V1E2,PSMD10,CALM3,FGF19,DUSP5,HDAC9,IGF1R,PRKCI,ERBB3,NCAM1,CAMK2G,MYO5A,PSMA5,RASGRF1,PSMB4,RAPGEF2,CALM1,PIK3R1,GRIN1,STRADB,BCAR1,PSMA4,EGFR,RASA1,GPLD1,TSC1,PRKAG2,INSR,FGFR2,FGF18,RAB31,GRIN2D,ATP6V1C1,TBC1D4,JAK3,CPEB2,DRD1 |
| 1.045e-04 | -9.17 | PROTEIN_KINASE_CASCADE | MSigDB lists | PROTEIN_KINASE_CASCADE | 289 | 66 | 17758 | 2588 |
SPRED1,NF2,SLC20A1,CARD10,DAPK2,RPS6KA2,TSPAN6,RGS3,IL31RA,DUSP10,TFG,F2R,MAP3K3,SOD1,MARK1,CXXC5,RIPK2,DUSP4,CD40,MAP3K6,STK17B,SOCS3,FYN,PLK2,SH2D3C,STK38,MADD,SECTM1,KIAA1804,STAT1,NOD2,MAP3K11,CANT1,MAPK13,TRAF5,PINK1,TAOK2,TRAF2,CCM2,PKN1,CARD8,IRAK1,PTEN,MAP3K9,DAPK1,ZDHHC13,SLC44A2,MAPK11,MDFIC,MAP3K7,EEF1D,MDFI,RHOA,STAT4,LITAF,MAPK8IP1,STK17A,BCL10,PRDX4,MAPKAPK2,SCG2,NMI,NR4A3,MAP3K5,CD81,NDFIP1 |
| 1.047e-04 | -9.16 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | 157 | 41 | 17758 | 2588 |
PCOLCE,DLGAP5,SPC25,PTTG1,TMX4,KIF23,PDGFRL,HMGN3,H1FX,HDAC9,TOP2A,RPS6KA2,CCNA2,METTL7A,DOK4,SORL1,TWIST1,ALDH7A1,BUB1,SPRY2,GM2A,IGSF3,HMMR,NFE2L3,PLK1,CENPA,S100A4,CDC20,AK4,AURKB,H2AFV,CDK1,NFIB,CYB5A,ACYP1,DBI,AURKA,MAOA,UBE2C,CBX5,ESPL1 |
| 1.050e-04 | -9.16 | kidney development | biological process | GO:0001822 | 256 | 61 | 16441 | 2455 |
NKX3-1,CDKN1C,LGR4,THRA,IQGAP1,LRP4,RET,EPHA4,SOX9,SDC4,GATA3,TGFBR1,OSR2,SDC1,PDGFB,SIX4,SGPL1,TP73,CTNNBIP1,BMP2,EPCAM,CA2,ITGA3,CTNNB1,NPNT,BMP7,GPC3,FRAS1,DLG1,TFAP2A,SMO,BAX,AKR1B1,ACTA2,TACSTD2,NOTCH3,TIPARP,SULF2,GCNT1,HES1,FMN1,DCHS1,AMER1,PYGO1,NPHP3,ILK,IRX3,TSC1,PROM1,FAT4,FGFR2,WFS1,WWTR1,STAT1,OVOL1,PKD2,GDF11,OSR1,SOX8,ADAMTS16,PCSK5 |
| 1.056e-04 | -9.16 | GSE22886_NAIVE_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_MEMORY_TCELL_DN | 193 | 48 | 17758 | 2588 |
HECA,ACVR1,PPP1R2,TCTN2,JRKL,EPHA4,PDIA3,CBLL1,GRK6,NUP62CL,CORO1B,IL17RB,ZFX,DAZAP1,ACAP2,TIMP1,CAPG,MDFIC,TAGLN2,CITED2,TRAM1,RASGRP1,CRTAP,UPF3A,ELK3,KIAA0040,SLC39A8,DSTN,MBNL3,SESN1,ALCAM,FRMD4B,IL1R1,RCBTB2,RBL1,LRIG1,PGRMC1,INPP4B,FAM117A,CLMN,CAB39,AGFG2,EIF4EBP2,ARF6,REEP4,AHR,RAD21,DOCK9 |
| 1.056e-04 | -9.16 | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP | 193 | 48 | 17758 | 2588 |
CIT,ATP2C2,ASB9,MORC4,KIF23,SORBS3,KIF2C,SYTL4,FAM101B,IL18R1,SLC35E4,IL17RB,PQLC2,RPS6KA2,FAM20C,KIF22,ARNT2,EPB41L4B,HLA-C,PIM1,CTTN,PHKA2,TLE6,GM2A,S100A6,TUBA4A,CPD,P2RX4,ALDH2,CEP89,TEP1,LITAF,CDC25C,CASP4,CMTM7,RASGRP2,GABARAPL1,PIAS3,PVRL2,BMP1,RELL1,GEM,RBM43,TMEM159,NRGN,PPP2R2D,CSRP2,IRF1 |
| 1.056e-04 | -9.16 | GSE22886_DC_VS_MONOCYTE_UP | MSigDB lists | GSE22886_DC_VS_MONOCYTE_UP | 193 | 48 | 17758 | 2588 |
MYL9,MRC2,AVPI1,EPAS1,CTSB,APOO,RASGRP3,MPP5,NENF,ISYNA1,MICALL2,LMNA,CALR,CTSC,MGAT4A,COL6A1,ADCK2,TAX1BP3,GOT1,ALDH3A2,FAM69A,NAGPA,PCCB,ZWINT,CTNNAL1,DENND1B,HMG20B,TNS1,ATP1B1,SLC17A5,SESN1,ABR,GABARAPL1,BCAR3,SWAP70,ALDH5A1,TWSG1,SPINT2,MAOA,MDH1,DONSON,AKIP1,SLC27A3,RAP1GAP,HSPB1,CD81,ANXA11,ACOT7 |
| 1.063e-04 | -9.15 | mesenchymal cell differentiation | biological process | GO:0048762 | 134 | 37 | 16441 | 2455 |
SEMA6B,ACVR1,RET,SOX9,TGFBR1,FAM101B,EFNB1,FGF19,GBX2,BMP2,TGFBR3,CTNNB1,BMP7,SMO,ADAM15,TWIST1,SEMA3G,SEMA3B,EPB41L5,HES1,S100A4,AMER1,LOXL2,EDNRA,PITX2,SEMA4D,FGFR2,CORO1C,TBX1,WWTR1,STAT1,FAM83D,NRG1,EFNA1,SOX8,OSR1,SEMA3A |
| 1.065e-04 | -9.15 | SIG_CHEMOTAXIS | MSigDB lists | SIG_CHEMOTAXIS | 45 | 17 | 17758 | 2588 |
INPPL1,AKT1,ARHGEF11,PIK3R1,RACGAP1,ITPR2,ITPR3,PAK6,PITX2,PTEN,LIMK1,MYLK,ITPR1,PAK2,PIK3CA,PIK3CD,ARHGAP4 |
| 1.068e-04 | -9.14 | ACTIN_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | ACTIN_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | 103 | 30 | 17758 | 2588 |
WASF3,PACSIN2,TAOK2,SORBS1,RHOA,NF2,SSH1,DSTN,EZR,TESK2,RACGAP1,ARHGDIB,SORBS3,MRAS,BCAR1,RASA1,RND1,ARHGEF10L,TSC1,RND3,LIMK1,DLG1,CAPG,PRKG1,ARAP1,FGD6,ARF6,SHROOM2,CCDC88A,FGD1 |
| 1.069e-04 | -9.14 | sclerosing | COSMIC cancer mutations | sclerosing | 62 | 21 | 17775 | 2585 |
ARAP3,AKT1,PIK3R1,RET,TP53,ASL,ERBB2,IDH1,GNA11,EGFR,FRMD4B,GNAS,CDKN2C,ZYX,CTNNB1,FGFR2,ITGA7,TMEM143,SMO,PIK3CA,NGEF |
| 1.077e-04 | -9.14 | HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP | 41 | 16 | 17758 | 2588 |
CENPA,IBTK,STAT4,SELL,CR2,PBX3,FAM101B,FGF19,CDK5R1,TGFBR3,CSF1,FAM102A,ARRB1,FXYD5,GAD1,NGEF |
| 1.077e-04 | -9.14 | HOLLMANN_APOPTOSIS_VIA_CD40_DN | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_DN | 246 | 58 | 17758 | 2588 |
GSDMD,PARP12,HOXB7,MPZL1,S100A11,GNPDA1,HLA-E,HLA-F,TP53,PSME1,OSR2,NOTCH2,MGST2,DENND2D,LGALS3BP,HDAC9,B3GALNT1,DNPEP,EFR3A,CTSC,BMP7,RRBP1,CD9,CDKN1B,HLA-C,PPP1CA,ARMCX6,RAG1,TFG,LRIF1,TRAM1,EEF1D,TMX1,FADS2,PGM1,MBP,AGPS,CYB5R2,LITAF,CCBL2,NPC2,SAV1,PCTP,CASP4,RASGRP2,ANKRD10,HLA-B,CASP7,SPINT2,STAT1,TDRD7,RYK,TLE1,PLXND1,AKIP1,SERPINB1,IFIH1,TMEM131 |
| 1.078e-04 | -9.14 | establishment of organelle localization | biological process | GO:0051656 | 342 | 77 | 16441 | 2455 |
DOC2A,DLGAP5,NDC80,P2RX7,KIF2C,SYTL4,CCNB1,SYTL2,AP1M2,CTNNB1,KIF14,DPYSL2,DLG1,DNM2,KIF22,LMAN1,TFG,PACSIN1,RAB27B,RASGRP1,SEC23A,PSRC1,CENPA,UXT,SYNE2,VPS4B,EZR,KIF13A,NUSAP1,MCFD2,TRIM9,WIPI1,AREG,CHMP4B,SYT13,TC2N,COPG1,GRN,TRAPPC10,CDCA8,PLD2,CTSZ,GPSM2,SPDL1,KIF5B,RB1,PDCD10,CTSC,LLGL2,CPLX1,NTN1,PPP6R1,SPRY2,SYTL3,MYO5A,TMED2,SUN2,RAB3B,SCRIB,COL7A1,BBS2,STX3,MAP1B,AP1AR,SERPINA1,FGFR2,HTT,SYT7,PVRL2,CDCA5,FAM83D,CENPE,GEM,NDE1,SHROOM2,ESPL1,SNPH |
| 1.079e-04 | -9.13 | Golgi cisterna | cellular component | GO:0031985 | 93 | 28 | 17570 | 2579 |
CHSY3,MOB4,NAGPA,B3GALT6,ATL1,SORT1,GOLIM4,FURIN,B4GALT4,BCAP31,NCS1,HLA-A,CHPF,GALNT3,NUCB1,INPP5E,FUT2,NECAB3,FUT8,CSGALNACT1,FUT1,ARAP1,CANT1,SORL1,B4GALT3,ST3GAL1,TMED2,GCNT1 |
| 1.084e-04 | -9.13 | GSE10325_BCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_BCELL_VS_MYELOID_DN | 188 | 47 | 17758 | 2588 |
LGALS3,CDKN1C,CTSB,BLVRB,HEXB,KCTD12,SIRPA,ICAM1,GNS,DRAM1,DAPK1,MTMR11,FAR2,PTPRE,NAGA,CCDC88A,DUSP1,CYP1B1,CPD,LAMP2,ALDH2,TRIM8,MAPKAPK3,S100A4,MPP1,PLAUR,SAT1,CDA,PDK3,BLVRA,C15orf39,FOS,RNPEP,CRISPLD2,NAAA,SERPINA1,PELI2,SECTM1,NOD2,ZDHHC7,CTSA,PLXND1,SLC27A3,SLC31A2,RTN3,CYBRD1,RRAGD |
| 1.084e-04 | -9.13 | GSE2826_WT_VS_BTK_KO_BCELL_DN | MSigDB lists | GSE2826_WT_VS_BTK_KO_BCELL_DN | 188 | 47 | 17758 | 2588 |
ELK4,CASP3,GOLIM4,PINK1,UGP2,EPAS1,CTSB,TRAF2,FHDC1,ABCG2,FLOT1,GATA3,NES,IL18,FLT3,DNAJB9,DAPK2,SPP1,ITM2C,PAQR7,CPD,B3GALT6,LAP3,S100A4,ATP1B1,BCL2L13,RNPEP,NFIX,TXK,DPYSL3,AHRR,GALNT3,FECH,ENPP1,CORO1C,AXL,P4HA2,PTER,MATN2,S100A5,AURKA,ARRB1,SERPINB6,CHMP4B,MAPK13,ATP1B3,RAB3IL1 |
| 1.085e-04 | -9.13 | TBCE (tubulin folding cofactor E) | protein interactions | 6905 | 12 | 8 | 16036 | 2547 |
GNPDA1,NFKBIA,TBCD,PYGL,AHCY,ARF6,TUBA4A,RAD23A |
| 1.085e-04 | -9.13 | PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1) | protein interactions | 9088 | 12 | 8 | 16036 | 2547 |
PLK1,CCNA2,PTEN,SPINT2,STEAP3,CCNB1,PLIN3,CDK1 |
| 1.091e-04 | -9.12 | response to lipid | biological process | GO:0033993 | 785 | 155 | 16441 | 2455 |
CASP3,TRIM24,RET,GATA3,IL18,CCNB1,PDGFB,SDC1,CALM2,CYP1A1,PCNA,TGFBR3,CTNNB1,CTGF,FOSB,ABCA2,CLDN4,DUSP10,TNFRSF18,ASH2L,ARNT2,THRB,CITED4,ASXL1,CASP9,IDH1,ABR,MDK,MAP2,AREG,TBX1,NOD2,NR2C2,PRKAA2,GRN,SOX9,PRKAA1,CALM3,CALR,TFAP4,SPP1,CA2,GATA2,PIM1,WNT3A,PAQR7,MAPKAPK3,MICB,CALM1,PDK3,ELK1,MEST,EGFR,FAS,FECH,GNAS,MMP15,MAPKAPK2,NCOA3,NFKBIA,DGAT2,AURKA,NR4A2,RARG,RPS6KA3,DRD1,NQO1,IL15,THRA,ERBB2,P2RX7,CCND1,CCNA2,SP100,PLCG2,SRR,SMO,CDKN1B,DAB2IP,GOT1,PDE4D,NFKB2,OSBPL7,LOXL1,F2R,CDKN2D,NR2C1,AKT1,RIPK2,FZD4,PTPRU,VPS4B,PTGER4,ERBB2IP,CD40,FZD7,SOCS3,PTGS2,ATP1A1,CDK19,AXL,PTK7,STAT1,NR3C2,ABCA1,OTUD5,ANXA3,PLSCR4,NKX3-1,SERPINB9,SELL,TGFBR1,GSTP1,ETS1,ICAM1,CXCL16,IRAK1,PTEN,BMP7,CST3,TFAP2A,BAX,HMGCL,IGFBP2,KLF9,CITED2,GFI1,DUSP1,RHOA,ADAM17,WNT10B,NR3C1,NR4A1,LITAF,PPARA,YES1,FOS,GPLD1,PITX2,RGS9,TIMP3,NR1D2,PRDX3,CTSV,NR4A3,E2F1,HOXB13,GPER1,CMPK2,OSR1,ARSB,PTGES,FOXA1,ABCG1,PHC1 |
| 1.093e-04 | -9.12 | Mitotic Metaphase and Anaphase | REACTOME pathways | R-HSA-2555396 | 173 | 45 | 8202 | 1235 |
SPC25,PSME2,CENPI,PTTG1,NDC80,ERCC6L,CDCA8,PSMD7,PSMD10,NUF2,PSME1,KIF2C,SPDL1,CENPN,LMNA,CKAP5,PSMD1,PSMC2,BUB1,KNTC1,NUP85,PSMA5,PLK1,CENPA,ZWINT,PSMB4,CENPC,B9D2,CDC20,AURKB,SKA1,PSMA4,LEMD2,PPP2R5A,PSMD3,CDCA5,CENPE,NUP37,NDE1,SGOL1,UBE2C,PSMC1,ESPL1,PPP2R5D,RAD21 |
| 1.097e-04 | -9.12 | NCAM signaling for neurite out-growth | REACTOME pathways | R-HSA-375165 | 266 | 63 | 8202 | 1235 |
SPRED1,COL9A3,AGRN,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,COL4A5,RASGRP3,PSME1,CACNB4,PDGFB,SPTB,DUSP5,FGF19,ITGA2B,CALM2,PDGFA,PSMD1,ARTN,SHC3,PSMC2,COL6A1,DUSP10,DAB2IP,ERBB3,CACNA1D,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,COL6A2,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.098e-04 | -9.12 | endosomal part | cellular component | GO:0044440 | 426 | 91 | 17570 | 2579 |
LAMP1,NDRG1,EPHA4,RET,ERBB2,MVB12B,ZFYVE9,SLC9A7,ZFYVE16,RAB15,ATP6V0B,ACAP2,TM9SF2,WDR44,STEAP2,ABCA2,SNX16,STEAP3,ECE1,MARCH2,RAB27B,SNX10,TMEM9,TMBIM1,LAMP2,SNX8,CLCN3,VPS11,KREMEN2,VPS4B,AP5M1,KIF13A,SLC11A2,RAB38,WIPI1,SLC9A6,CHMP4B,IRF7,ARF6,RRAGD,STARD3NL,GOLIM4,PACSIN2,SORT1,TRAPPC10,CD63,TAB3,GGA1,TMEM55B,BACE1,HLA-F,CTSB,HLA-E,ATP9A,RAB23,FAM21C,VPS26A,PARM1,HLA-A,MARCH8,SNX13,IRAK1,SNX18,ZNRF2,OCRL,KIAA0319,PLEKHF1,HLA-C,PIKFYVE,WNT3A,MAP3K7,TPCN1,SUN2,MMD,IFITM3,ANTXR1,CPTP,STEAP1,RHOB,EGFR,CTSL,HLA-B,INSR,RAB11FIP2,RAP2C,APPL2,PLD1,PLIN3,FZD5,NDFIP1,EHD1 |
| 1.100e-04 | -9.11 | PROTEIN_LOCALIZATION | MSigDB lists | PROTEIN_LOCALIZATION | 209 | 51 | 17758 | 2588 |
NFKBIE,PEX6,GGA1,TP53,PDIA3,APBA1,BARD1,ERP29,SNX9,AIP,ZFYVE9,APPBP2,PDIA4,ATG4A,ZFYVE16,CALR,AP1M2,CARD8,CDH1,PPP1R10,LMAN2L,KIF13B,REEP1,BCL6,ARL4D,F2R,TRAM1,RPGR,KDELR1,MDFI,ATG4D,NAGPA,AKT1,COG2,STRADB,ICMT,EGFR,VCP,OPTN,KLHL2,SCG2,SHROOM3,NOD2,ARFGAP3,KPNA2,CTSA,LTBP2,CD81,SHROOM2,ABCA1,ABCG1 |
| 1.102e-04 | -9.11 | PHONG_TNF_TARGETS_UP | MSigDB lists | PHONG_TNF_TARGETS_UP | 62 | 21 | 17758 | 2588 |
NKX3-1,SDC4,CCNL1,FOS,DUSP5,ICAM1,CD83,IER3,BMP2,BTG1,BTG3,ETS2,ZFP36,PLK2,NFKBIA,FJX1,DUSP10,GEM,NFKB2,DUSP1,IRF1 |
| 1.107e-04 | -9.11 | Cyclin-like | interpro domains | IPR013763 | 41 | 16 | 18293 | 2672 |
CCNE2,CCNC,CCNI,CCNO,CCNJL,CCNL1,CCNF,CCNB1,CDK5R1,CCND1,RB1,CCNA2,CCNB3,RBL1,CCNB2,CASD1 |
| 1.112e-04 | -9.10 | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | 183 | 46 | 17758 | 2588 |
SERPINE2,THRA,INPP5D,CD82,DGKA,NOTCH2,FBLN1,PER2,WWP2,FAM111A,SPP1,FRY,LRRN2,MKRN3,RPL39,ALDH1A3,AIM1,TFAP2A,FAM102A,RFX5,PIK3CD,TSPAN1,SCARA3,GCA,RASGRF1,ING1,TCFL5,CXorf57,UTRN,CR2,TCF7,KIF13A,LEPR,ENDOD1,BTG1,BANK1,SLC4A4,DCK,CSF1,NEIL3,DTX4,TRAF5,CBX7,PKIA,KLF7,FAM134B |
| 1.112e-04 | -9.10 | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP | 183 | 46 | 17758 | 2588 |
KLF2,LASP1,ACVR1,TM2D2,LGALS3,CD63,GNPDA1,UBASH3B,HEXB,TGFBR1,MAP1LC3B,S100A2,SNX9,BCAP31,SPP1,EFR3A,MGAT1,FBXO7,ADCK2,SGK1,IL17RA,BRI3,TMBIM1,WBP5,SNX8,TGIF1,MFI2,LONRF3,PLEKHO1,SERTAD3,LHFPL2,SNX12,STX3,RHOB,BCAR3,SCARB2,SLCO4A1,PEX5,PPP2R5A,LIMK1,CORO1C,WDR91,NRBP1,CCDC97,ZC3HC1,RRAGD |
| 1.126e-04 | -9.09 | carcinoma_in_situ | COSMIC cancer mutations | carcinoma_in_situ | 94 | 28 | 17775 | 2585 |
PRKAA2,AKT1,TESK1,RET,PIK3R1,TP53,ERBB2,TESK2,GRK6,NOTCH2,PKN1,IDH1,FLT3,MAP3K6,GNA11,EGFR,GNAS,EPHA10,CTNNB1,IRAK1,JAK1,CDH1,PTEN,FGFR2,SMO,PIK3CA,MAPK13,JAK3 |
| 1.126e-04 | -9.09 | ductal_carcinoma_in_situ | COSMIC cancer mutations | ductal_carcinoma_in_situ | 94 | 28 | 17775 | 2585 |
PRKAA2,AKT1,TESK1,RET,PIK3R1,TP53,ERBB2,TESK2,GRK6,NOTCH2,PKN1,IDH1,FLT3,MAP3K6,GNA11,EGFR,GNAS,EPHA10,CTNNB1,IRAK1,JAK1,CDH1,PTEN,FGFR2,SMO,PIK3CA,MAPK13,JAK3 |
| 1.126e-04 | -9.09 | breast-carcinoma_in_situ-ductal_carcinoma_in_situ | COSMIC cancer mutations | breast-carcinoma_in_situ-ductal_carcinoma_in_situ | 94 | 28 | 17775 | 2585 |
PRKAA2,AKT1,TESK1,RET,PIK3R1,TP53,ERBB2,TESK2,GRK6,NOTCH2,PKN1,IDH1,FLT3,MAP3K6,GNA11,EGFR,GNAS,EPHA10,CTNNB1,IRAK1,JAK1,CDH1,PTEN,FGFR2,SMO,PIK3CA,MAPK13,JAK3 |
| 1.133e-04 | -9.09 | positive regulation of cellular catabolic process | biological process | GO:0031331 | 310 | 71 | 16441 | 2455 |
DLGAP5,CNOT8,PNPLA2,PSME2,CUL1,P2RX7,PSME1,CCNB1,SNX9,BCAP31,EPM2A,PSMD1,RALB,ZFP36,PSMC2,DAB2IP,TWIST1,OSBPL7,PLK1,SIRT1,VPS11,TRIM8,AKT1,CDC20,EZR,RNF19B,CDK1,VCP,IRS2,PLK2,PSMD3,PSMC1,ARNT,PRKAA2,TNRC6C,PINK1,SCOC,DNAJB2,SH3D19,PRKAA1,PSMD7,PSMD10,TRIB2,RB1,RNF128,CTSC,PTEN,BAX,TRIM21,PLEKHF1,PHKG2,PSMA5,SOCS5,PSMB4,GCLC,NUB1,FURIN,PIP4K2C,PPARA,PRICKLE1,TP53INP2,PSMA4,PLIN5,GPLD1,INSR,SH3BP4,AURKA,UBE2C,CD81,ESPL1,TOB1 |
| 1.137e-04 | -9.08 | ATF2_UP.V1_DN | MSigDB lists | ATF2_UP.V1_DN | 178 | 45 | 17758 | 2588 |
PLA2G4A,PLSCR4,ARHGEF3,MRPL44,GALNT12,SERPINB9,SOD2,PKP2,KCTD12,FAM198B,PLA2G16,HOXB2,DENND2D,ZNF432,FRY,ADAM15,IGFBP2,LIMCH1,ARNT2,PIM1,IL1RAP,ERAP2,CTH,CYP1B1,SLC39A8,AK4,PLS1,ROR1,FOS,NFIB,EDNRA,IRS2,IL1R1,SLCO4A1,PTGS2,PDLIM3,GPRC5B,PTER,PELI2,SPINT2,RAB11FIP1,CSGALNACT1,PER3,SHOX2,CYBRD1 |
| 1.142e-04 | -9.08 | GNF2_STAT6 | MSigDB lists | GNF2_STAT6 | 80 | 25 | 17758 | 2588 |
IQGAP1,HLA-E,HLA-F,INPP5D,SELL,EMP3,ARHGDIB,GRK6,CASP4,CMTM6,HLA-A,LCP1,HLA-B,RAC2,TAPBP,ACAP2,STAT6,PAK2,RIN3,FXYD5,OSTF1,HLA-C,ARPC2,ARF6,ANXA11 |
| 1.148e-04 | -9.07 | regulation of cell division | biological process | GO:0051302 | 294 | 68 | 16441 | 2455 |
CCNC,DLGAP5,PTTG1,CCNL1,PDGFB,STIL,NPM2,CALM2,SUSD2,CCND1,PDGFA,RPS6KA2,KIF14,ZBTB18,HSPA2,PLK1,PSRC1,AKT1,CDC20,VPS4B,NUSAP1,AURKB,PKMYT1,ANLN,CDC25C,PGF,MDK,CHMP4B,MAD2L1BP,E2F8,PRKAR1A,NKX3-1,MACC1,CIT,PSMD10,KIF23,CALM3,RACGAP1,CALR,RB1,E2F7,IGF1R,PTEN,BMP7,MSH2,NEK2,BUB1,PIM1,KNTC1,PDGFC,RHOA,ADAM17,ASPM,CALM1,RGCC,KIF20B,BORA,KIF11,EGFR,NCOA3,INSR,FGFR2,CDCA5,AURKA,PKD2,CENPE,UBE2C,ESPL1 |
| 1.151e-04 | -9.07 | innate immune response-activating signal transduction | biological process | GO:0002758 | 241 | 58 | 16441 | 2455 |
DDX58,UNC93B1,HSP90B1,TAB3,TRIM5,CTSB,RPS6KA1,PSME2,PSMD7,CALM3,CUL1,PSMD10,PSME1,ITPR2,PRKACA,CALM2,RPS6KA2,PSMD1,IRAK1,PIK3AP1,PSMC2,PLCG2,PAK2,MAPK11,MAP3K7,SCARA3,MAPK7,LGMN,NFKB2,CNPY3,SYK,PSMA5,TNIP1,PSMB4,RIPK2,MAPKAPK3,ITCH,CALM1,ELK1,ITPR3,DUSP4,FOS,PSMA4,BCL10,CTSL,MAPKAPK2,FYN,PELI2,PSMD3,NFKBIA,ITPR1,UBE2D2,NOD2,IRF7,IFIH1,PPP2R5D,PSMC1,RPS6KA3 |
| 1.152e-04 | -9.07 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP | 71 | 23 | 17758 | 2588 |
HMMR,CCNE2,CTHRC1,MRPL44,ASPM,DENND1B,RET,EIF2AK1,RACGAP1,NUSAP1,IFIT3,ANLN,FANCI,TOP2A,B3GALNT1,RALGPS2,FUT8,UBE2D2,UNC5B,FAR2,GLCCI1,MELK,ATP2B1 |
| 1.158e-04 | -9.06 | cellular response to peptide | biological process | GO:1901653 | 470 | 100 | 16441 | 2455 |
SPRED1,SORBS1,SLC2A4,SLC2A8,PSME2,WDTC1,NRG2,ERBB2,RASGRP3,PSME1,PRKACA,PDGFB,SPTB,GNB2,CALM2,PDGFA,ATP6V0B,PSMD1,SHC3,PSMC2,KLF3,PIK3CA,AKR1B1,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,RIPK2,AKT1,PRKAR2B,POR,CASP4,RHEB,SOCS3,IRS2,ENPP1,FYN,IDE,JAK1,PSMD3,NOD2,STAT1,CAB39,EIF4EBP2,SPTBN5,NRG1,PSMC1,GAB1,RRAGD,PRKAR1A,PRKAA2,KLF2,RASA2,PRKAA1,PSMD7,ATP6V1E2,CALM3,PSMD10,DUSP5,FGF19,HDAC9,IGF1R,PRKCI,ERBB3,NCAM1,CAMK2G,MYO5A,PSMA5,RASGRF1,ADAM17,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,STRADB,YES1,BCAR1,PSMA4,EGFR,RASA1,GPLD1,GNAS,TSC1,INSR,PRKAG2,FGFR2,FGF18,RAB31,NR4A3,GRIN2D,NR4A2,GPER1,ATP6V1C1,JAK3,TBC1D4,CPEB2,DRD1 |
| 1.161e-04 | -9.06 | cellular response to organonitrogen compound | biological process | GO:0071417 | 612 | 125 | 16441 | 2455 |
SPRED1,SORBS1,SLC2A4,SSH1,SLC2A8,PSME2,WDTC1,NRG2,ERBB2,RASGRP3,PSME1,ITPR2,BCL2L1,PRKACA,PDGFB,SPTB,GNB2,CALM2,PDGFA,ATP6V0B,PSMD1,CDH1,CTNNB1,SHC3,PSMC2,KLF3,PIK3CA,DNM2,AKR1B1,DAB2IP,GOT1,PDE4D,RASGEF1A,RASGRP1,FRS3,SOD1,RIPK2,AKT1,DMTN,EZR,PRKAR2B,POR,CASP4,RHEB,SOCS3,IRS2,ENPP1,PTGS2,IDE,FYN,JAK1,PSMD3,NOD2,STAT1,CAB39,EIF4EBP2,SPTBN5,NRG1,PSMC1,GAB1,RRAGD,PRKAR1A,PRKAA2,KLF2,HSP90B1,CPEB4,RASA2,SOX9,PRKAA1,PSMD7,ATP6V1E2,CALM3,GABRG2,PSMD10,DUSP5,FGF19,ICAM1,HDAC9,CAPN2,IGF1R,COL6A1,PRKCI,ERBB3,NCAM1,CAMK2G,MYO5A,PSMA5,HCN3,P2RX4,PDGFC,RASGRF1,ADAM17,SHMT1,PSMB4,WNT10B,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,STRADB,YES1,BCAR1,PSMA4,EGFR,RASA1,GPLD1,GNAS,TSC1,INSR,PRKAG2,FGFR2,FGF18,SH3BP4,RAB31,NR4A3,GRIN2D,NR4A2,GPER1,ATP6V1C1,JAK3,TBC1D4,CPEB2,COL16A1,DRD1 |
| 1.161e-04 | -9.06 | OKUMURA_INFLAMMATORY_RESPONSE_LPS | MSigDB lists | OKUMURA_INFLAMMATORY_RESPONSE_LPS | 173 | 44 | 17758 | 2588 |
MTM1,TXN,RUNX2,GALNT12,SCD5,ETV5,SDC4,PRSS22,IL27RA,DSE,PHLDA1,NFAT5,FZD6,SIRPA,SGPL1,TNS3,ACTA2,CITED2,MAST4,KCTD3,RASGRP1,PPIF,NFE2L3,ORAI2,TNIP1,PTGER4,SLC11A2,PKMYT1,RAB38,ALCAM,CYB5A,SPAG1,OPTN,NCOA3,RGS9,FA2H,DHRS2,RAB31,MAOA,TLE1,GDF11,PDXK,CCNB2,APOL2 |
| 1.171e-04 | -9.05 | V$P300_01 | MSigDB lists | V$P300_01 | 236 | 56 | 17758 | 2588 |
CDK17,ZNF395,HEBP1,CAST,TSC22D3,DGKA,WDTC1,BLCAP,EGR3,BCL2L1,BAHD1,SIX4,PDCD10,IRAK1,ANKS1B,TSPAN6,DPYSL2,GPC3,BHLHE41,LHX6,SLC44A1,TRIM3,CKS1B,ADAM15,TWIST1,TNFRSF12A,PIK3CD,RBMS2,CCDC88A,HCN3,EBAG9,CXXC5,FURIN,ERBB2IP,BORA,PNKD,GPLD1,RASGRP2,EPN3,PRKAG2,SLC9A6,NFKBIA,ARAP1,APPL2,PPP1CB,NXPH4,SERPINI1,SP6,C1orf43,FZD5,ARF6,RGS14,STARD13,RARG,JARID2,FAM134B |
| 1.190e-04 | -9.04 | membrane microdomain | cellular component | GO:0098857 | 272 | 63 | 17570 | 2579 |
CASP3,SPRED1,SCN5A,SORBS1,SLC2A4,PACSIN2,NF2,CTSB,TRAF2,RET,SDC4,LRP4,FLOT1,EFHD2,ERBB2,HDAC6,PRKACA,EMP2,EFNB1,ICAM1,CAPN2,CDH1,IGF1R,CTNNB1,KCNN4,DLG1,SMO,TRPC1,PIKFYVE,CTSD,FLOT2,F2R,LAMP2,CD55,ADAM17,PLSCR1,RGMB,FURIN,EZR,PRKAR2B,ATP1B1,CBL,DAG1,EGFR,FAS,BCL10,PTGS2,ATP1A1,RTN4RL1,INSR,FYN,HPSE,CORO1C,PRKCDBP,SLC27A1,EFNA5,MAL2,ATP1B3,UNC5B,ABCA1,PROM2,PRKAR1A,DRD1 |
| 1.193e-04 | -9.03 | ESTABLISHMENT_OF_CELLULAR_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_CELLULAR_LOCALIZATION | 351 | 77 | 17758 | 2588 |
TP53,ARFGEF1,SYTL4,BCL2L1,BAIAP3,BARD1,ERP29,ZFYVE9,APPBP2,ZFYVE16,NAPG,AP1M2,CDH1,LMAN2L,STEAP2,BCL6,ABCA2,TINAGL1,ARL4D,LMAN1,F2R,TRAM1,ATG4D,AKT1,COG2,UXT,VPS4B,HTATIP2,KIF1C,ERP44,NUSAP1,ICMT,VCP,OPTN,KCNMB4,NOD2,KPNA2,ABCA1,NFKBIE,PEX6,GGA1,PDIA3,APBA1,ATG4A,M6PR,PDIA4,CALR,KIF5B,DOPEY2,CARD8,PPP1R10,KIF13B,CPLX1,RPGR,TMX1,KDELR1,MDFI,NAGPA,SUN2,ZWINT,VAMP3,STRADB,AKAP3,NPC2,RHOB,KLHL2,TSC1,SCG2,CDCA5,ARFGAP3,CTSA,CENPE,LTBP2,ARSB,SHROOM2,NRBP1,ABCG1 |
| 1.201e-04 | -9.03 | immune system development | biological process | GO:0002520 | 601 | 123 | 16441 | 2455 |
CASP3,ADD1,HOXB7,EPAS1,IL15,LFNG,THRA,RET,TP53,GATA3,FLT3,CACNB4,PDGFB,TNFSF9,SPTB,TGFBR3,CTNNB1,ARTN,LMO4,PLCG2,MITF,IL31RA,POLL,TMEM143,BCL6,RTKN2,ASH2L,PIK3CD,NFKB2,SNX10,TIPARP,SPEF2,SOD1,LGALS8,OSTM1,DMTN,CASP9,NFE2L1,PTGER4,CR2,SLC11A2,GLO1,PYGO1,ANLN,FZD7,CMTM7,SFXN1,STAT6,TBX1,HOXA9,AXL,PTBP3,DHTKD1,RPL22,F2RL1,KLF2,DYRK3,RUNX2,TNRC6C,CDKN1C,BVES,ARHGEF7,TGFBR1,JAG2,NOTCH2,PKN1,HERC6,MERTK,IL18R1,SIX4,HDAC9,SGPL1,MECOM,TOP2A,CD109,RB1,FAM20C,GATA2,GPC3,BAX,MSH2,FNIP1,ERCC2,WNT3A,RAG1,CITED2,GFI1,SYK,MSH6,FARP2,HES1,ADAM17,RHOA,WNT10B,CRIP2,PIK3R1,RC3H2,TTC7A,RUNX3,EIF2AK1,FOXL1,TXK,FAS,PITX2,FECH,CD8A,ONECUT1,TSC1,SWAP70,FGFR2,TWSG1,PRDX3,DHRS2,CSF1,PPP2R3C,LRRK1,FZD5,JAK3,CCNB2,SLC25A38,MELK,JARID2,IRF1 |
| 1.204e-04 | -9.02 | REACTOME_ER_PHAGOSOME_PATHWAY | MSigDB lists | REACTOME_ER_PHAGOSOME_PATHWAY | 58 | 20 | 17758 | 2588 |
SEC61B,PSMB4,SEC61G,PSME2,HLA-F,TAP1,PSMD7,PDIA3,PSMD10,PSME1,PSMA4,HLA-A,CALR,HLA-B,PSMD1,PSMD3,PSMC2,HLA-C,PSMC1,PSMA5 |
| 1.204e-04 | -9.02 | NAKAMURA_ADIPOGENESIS_EARLY_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_EARLY_UP | 58 | 20 | 17758 | 2588 |
WASF3,ELK3,PRSS23,PIK3R1,SOD2,FAM198B,IL22RA1,IL1R1,IRS2,FYN,TGFBR3,CTNNB1,ZFP36,PDE4D,PPP1CA,NPTXR,LIFR,ABCA1,CYBRD1,GM2A |
| 1.208e-04 | -9.02 | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP | 194 | 48 | 17758 | 2588 |
TXN,SERPINE2,UGP2,AGRN,PEX6,PSME2,SOD2,ARL4C,TAP1,SELL,PHF1,FANCI,ICAM1,IER3,CYHR1,BTG3,ENTPD4,SRPX,CTNNB1,PFKL,PLK4,AKR1B1,ANKRD12,GYS1,CLDN4,IFIT1,PIM1,LOXL1,SCYL3,DOCK4,OPLAH,TNIP1,PRSS23,IFITM3,SLC39A8,STAT4,SAT1,LITAF,BNIP3L,FBXO9,FNDC3A,PSMA4,CD8A,BTG1,KBTBD2,SPINT2,TMEM159,EHD1 |
| 1.208e-04 | -9.02 | GSE7852_TREG_VS_TCONV_THYMUS_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_THYMUS_UP | 194 | 48 | 17758 | 2588 |
CCDC109B,TTC39B,LGALS3,NOTCH2,BCL2L1,PHLPP1,PLA2G16,IL18R1,DUSP5,PPP2R3A,IGF1R,ITGB8,OSBPL3,MDFIC,NTN4,TSPAN13,KLF9,PIM1,MGAT5,S100A6,IGSF3,GCNT1,DUSP1,TGIF1,PLSCR1,S100A4,PTPN9,MBNL3,PTGER4,DUSP4,PRKRA,PCTP,RNPEP,SPNS3,CASP4,CD83,GABARAPL1,IL1R1,HLA-B,PRKAG2,DGAT2,NR4A2,SH3BGRL2,GEM,TTC39C,AHR,ACOT7,CSRP2 |
| 1.208e-04 | -9.02 | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN | 194 | 48 | 17758 | 2588 |
DYNLRB1,ARHGEF3,HJURP,S100A11,ST14,ARMC7,MCTP2,KIF23,FAM102B,KCTD12,TP53I11,PLA2G16,B4GALNT1,SPP1,ADD3,PTEN,TACC2,CDK16,RIMS3,PHTF1,FXYD5,IRF2,TRIM21,AK3,SCYL3,FGFR1OP2,S100A6,DDB2,OPLAH,PLEKHA6,GGH,ARHGDIB,EPHA1,ZDHHC3,NAAA,CAMK2N2,POPDC3,STAT1,TRIOBP,OVOL1,CLMN,GRAMD1C,AKIP1,CCNB2,MYL12B,STARD3NL,CTDSP1,ADAMTS16 |
| 1.210e-04 | -9.02 | ENZYME_ACTIVATOR_ACTIVITY | MSigDB lists | ENZYME_ACTIVATOR_ACTIVITY | 123 | 34 | 17758 | 2588 |
ARAP3,RALBP1,RASA2,RGS20,ARFGEF1,RASGRP3,RACGAP1,ARHGEF10L,RGS12,CARD8,RGS3,ARL1,RGS5,DOCK4,RAPGEF2,CASP9,PRKRA,CDK5R1,ABR,RASA1,BCL10,MMP15,RGS9,MMP17,MADD,PPP2R4,ARAP1,ARFGAP3,CTSA,ARHGAP4,RGS14,MAP3K5,RAP1GAP,AIFM3 |
| 1.217e-04 | -9.01 | MAPK8 (mitogen-activated protein kinase 8) | protein interactions | 5599 | 179 | 48 | 16036 | 2547 |
ELK4,CASP3,BMF,KCNAB3,SCOC,TRAF2,JKAMP,RET,TP53,IL27RA,BCL2L1,ZNF219,GSTP1,HDAC9,TP73,CDKN2C,RB1,APLP2,CTNNB1,DUSP10,CDKN1B,MAP3K7,DUSP1,GFPT1,SIRT1,SUN2,ELK3,RHOA,AKT1,NR3C1,NR4A1,ITCH,PIK3R1,EZR,PKMYT1,DUSP4,ELK1,CBL,BCAR1,MAPK8IP1,EGFR,MAP1B,FAS,HSF4,NCOA3,PIAS2,HDAC1,WDR62 |
| 1.217e-04 | -9.01 | SH3 domain binding | molecular function | GO:0017124 | 116 | 33 | 16491 | 2452 |
INPPL1,PLSCR4,INPP5D,CIT,PTTG1,REPS1,SH3KBP1,SIRPA,VASP,NOXA1,ELMO2,SH3BP1,FUT8,DNM2,ADAM15,ESPN,DAB2IP,OSTF1,PDE4D,DOCK4,ADAM17,PLSCR1,CRB3,FMN1,SH3BGRL,CASP9,ILK,CBL,BCAR1,DPYSL3,CNTNAP1,CCDC6,SH3BGRL2 |
| 1.219e-04 | -9.01 | CELLULAR_LOCALIZATION | MSigDB lists | CELLULAR_LOCALIZATION | 368 | 80 | 17758 | 2588 |
TP53,ARFGEF1,SYTL4,BCL2L1,BAIAP3,BARD1,ERP29,ZFYVE9,APPBP2,ZFYVE16,NAPG,AP1M2,CDH1,LMAN2L,REEP1,STEAP2,BCL6,ABCA2,TINAGL1,ARL4D,LMAN1,F2R,TRAM1,ATG4D,AKT1,COG2,UXT,VPS4B,HTATIP2,KIF1C,ERP44,NUSAP1,ICMT,VCP,NIN,OPTN,KCNMB4,NOD2,KPNA2,ABCA1,NFKBIE,PEX6,GGA1,PDIA3,APBA1,ATG4A,M6PR,PDIA4,CALR,KIF5B,DOPEY2,CARD8,PPP1R10,KIF13B,CPLX1,RPGR,TMX1,KDELR1,MDFI,NAGPA,SUN2,ZWINT,VAMP3,STRADB,AKAP3,NPC2,EGFR,RHOB,KLHL2,TSC1,SCG2,CDCA5,ARFGAP3,CTSA,LTBP2,CENPE,ARSB,SHROOM2,NRBP1,ABCG1 |
| 1.229e-04 | -9.00 | REGULATION_OF_MOLECULAR_FUNCTION | MSigDB lists | REGULATION_OF_MOLECULAR_FUNCTION | 318 | 71 | 17758 | 2588 |
CCNE2,SIGIRR,SPRED1,RALBP1,TP53,ERBB2,CARD10,PICK1,CCND1,CDKN2C,RGS3,SERINC2,F2R,CDKN2D,CKS2,SOD1,CASP9,PRKCQ,PIF1,PKMYT1,CDC25C,MAP3K6,VCP,EDNRA,RBL1,PPP2R4,MADD,KIAA1804,STAT1,MAP3K11,NOD2,GLA,AIFM3,FGD1,TAOK2,CDKN1C,TRAF2,HERC5,TRIB2,PKN1,DIRAS3,RB1,CARD8,IRAK1,PTEN,PAK2,BAX,MAP3K9,CKS1B,MDFIC,HEXIM2,MAP3K7,PLCB2,CCDC88A,MDFI,STRADB,EGFR,CDK5R1,BCL10,GNAS,CDK5RAP1,TSC1,LDLRAP1,PRDX3,ARAP1,FGD6,MAP3K5,CD81,HIPK3,IFI6,EGLN1 |
| 1.229e-04 | -9.00 | TTTGCAC,MIR-19A,MIR-19B | MSigDB lists | TTTGCAC,MIR-19A,MIR-19B | 499 | 103 | 17758 | 2588 |
CAST,SUZ12,ARFGEF1,C5orf30,TESK2,BLCAP,TGOLN2,CCNL1,GRK6,SDC1,FAM46C,ELMOD2,ZFYVE9,PAK6,WEE1,CTGF,WDR44,ENPP5,ANKRD12,TNPO2,ACSL4,TLN2,STK35,SMARCA2,TNIP1,NRBF2,RNF11,RNF165,VPS4B,B3GALNT2,DAG1,RAB2B,ABR,SOCS3,HLF,MID1IP1,CDK19,STK38,SLC9A6,FAM114A1,LRIG1,CAB39,FAM195A,CHMP4B,SLC31A2,E2F8,CBX7,ABCA1,RUNX2,CPEB4,SH3D19,ITGA6,BACE1,CCM2,MIER3,TTYH3,ANO1,PARM1,NRP2,SLC9A2,OCRL,PRC1,SGK1,TNFRSF12A,MDFIC,NPTN,MYLIP,PPP6R1,MPHOSPH9,CCDC88A,IGSF3,SOCS5,TRAK2,DPYSL5,ACBD5,TGIF1,ELK3,MLEC,SYBU,PPARA,UBE2A,PDE5A,KBTBD8,FBXO8,RUNX3,FAM73B,FNDC3A,RHOB,USP6,BTG1,TSC1,CSNK1G1,RAP2C,ITPR1,UBE2D2,CLIP4,SFMBT1,PGM2L1,ZDHHC7,NR4A2,LRRK1,NIPA1,SNPH |
| 1.231e-04 | -9.00 | BORCZUK_MALIGNANT_MESOTHELIOMA_UP | MSigDB lists | BORCZUK_MALIGNANT_MESOTHELIOMA_UP | 296 | 67 | 17758 | 2588 |
CCNE2,S100A11,CNOT8,C5orf30,MORF4L2,CCNB1,CDKN2C,SS18,WEE1,ACAP2,PCNA,ARL1,RP2,F2R,CKS2,LAMP2,NEK4,ACBD3,GLO1,LOXL2,CCNF,GTF2A2,H2AFV,DDOST,IARS2,KPNA2,MPZL1,PPP1R2,SEC61G,PSMD10,CRABP2,S100A2,FZD6,KIF5B,TOP2A,CALD1,PAK2,H2AFY,CKS1B,AHCY,MSH6,SMC4,PIGC,QSOX1,ZWINT,LPGAT1,UBE2A,VAMP3,BLVRA,KIF11,RASA1,STK17A,PRDX4,MAPKAPK2,MAGED2,FNTA,DCK,PRPS2,DBI,UBE2D2,PGRMC1,OSMR,HMGA1,ITGAV,UBE2C,RPS6KA3,RAD21 |
| 1.243e-04 | -8.99 | GSE25087_FETAL_VS_ADULT_TREG_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_UP | 189 | 47 | 17758 | 2588 |
CASP3,FARP1,FAF2,HSP90B1,AGRN,NFKBIE,PSME2,LRP4,CTDSPL,SDC4,APOO,C5orf30,PSME1,NOTCH2,GSTP1,SLC25A43,KIAA1147,IER3,CYP1A1,RALGPS2,ZNF823,DACT1,BRD7,TNFRSF18,CTTN,PDIA6,MCCC2,LAMP3,PPIF,RHOA,BTNL9,DRAP1,FURIN,GLO1,ERP44,ILK,PTGFRN,ADRBK2,VCP,MAN2A2,PRDX3,ACYP1,UTP14C,DOLPP1,STAT1,CMPK2,RAD21 |
| 1.243e-04 | -8.99 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 189 | 47 | 17758 | 2588 |
GAA,MTM1,RUNX2,PPP1R12A,FAM160B1,NLRX1,NDC80,WDTC1,SAMD9,NOTCH2,CAMK1D,LBR,SNX18,CASC4,CNPY3,PLCB2,APOBEC3G,XKR8,PHF20L1,TIMP2,TACC1,NRBF2,SH3BGRL,PYGL,STK17B,CYP4F3,RASA1,PLIN5,LCP1,CRISPLD2,KLHL2,GALNT3,TAPBP,CARHSP1,MSL1,MPRIP,PRCP,STK38,FAM117A,CAB39,ARRDC1,KPNA2,GRAMD1C,RELL1,ARPC2,CHPT1,CD33 |
| 1.243e-04 | -8.99 | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP | 189 | 47 | 17758 | 2588 |
SLC35D2,ANKRD13D,TRIM2,ADD1,S100A11,CENPI,MCTP2,PTTG1,HEXB,NDRG2,PGAP1,PSIP1,GNS,OTUD1,CYP1A1,GRHL1,RINL,TNFRSF12A,HSPA13,TAGLN2,TMEM64,C12orf75,SLC45A3,TPCN1,SMC4,SEC23A,CASP9,SPATA13,CCDC34,NEURL1B,STK17B,SNX12,PIAS3,NUDT16,DNAJC10,LDLRAP1,FNTA,FAM114A1,UBE2D2,S100A5,DTX4,PGM2L1,SPCS3,CBX7,SNX30,RPS6KA3,KLF7 |
| 1.243e-04 | -8.99 | SWEET_LUNG_CANCER_KRAS_DN | MSigDB lists | SWEET_LUNG_CANCER_KRAS_DN | 419 | 89 | 17758 | 2588 |
MYL9,SORBS1,PAPSS2,EPAS1,ARFGEF1,NDRG2,KCTD12,IL27RA,SEPT4,EMP2,FAM46C,CDK14,RCN1,ST5,NPNT,TSPAN6,CYP2S1,IL6ST,LOXL1,TIAM1,CPE,SMARCA2,COL6A2,USP18,SESN1,ANKRD10,FYN,WWTR1,PPP1CB,PRKCDBP,LIFR,ABCA1,KLF2,ARHGEF3,CDKN1C,IGFBP6,TNFRSF19,ETS1,PSIP1,TSPAN7,RABGGTA,TOP2A,CA2,CYR61,GPC3,ACTA2,BUB1,IGFBP2,ALDH7A1,TSPAN13,LIMCH1,KLF9,RAG1,NTN1,KANK3,ABCC1,DUSP1,IFITM3,VAMP3,PIP4K2C,SPA17,STMN3,CALCRL,GGH,IFIT3,NFIB,C3orf58,LEPR,PRX,RHOB,FAS,PROM1,TIMP3,ETS2,TWSG1,COL13A1,ACVRL1,NFKBIA,MATN2,PGRMC1,ARRB1,PKD2,FHL1,IFIH1,SHOX2,PTGES,AHR,PKIA,KLF7 |
| 1.244e-04 | -8.99 | GACAATC,MIR-219 | MSigDB lists | GACAATC,MIR-219 | 138 | 37 | 17758 | 2588 |
SCN5A,RBM24,UBASH3B,ZCCHC24,SH3D19,ELOVL7,EPHA4,ETV5,UBE2Z,EGR3,FAM91A1,ELMOD2,DAZAP1,FAM160A2,OCRL,KLF9,PDE4D,SLC39A10,CAMK2G,THRB,CXXC5,TACC1,PTPRU,FZD4,LPGAT1,FURIN,TMEM98,RGAG1,KBTBD8,ELK1,DCP2,SP4,DDAH1,APPL2,ZC3H12B,CPEB2,NR2C2 |
| 1.249e-04 | -8.99 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | 85 | 26 | 17758 | 2588 |
CD55,CPEB4,TSC22D3,FRMD6,SNTB2,ARMC7,EPHA4,GATA3,BCL2L1,ATP1B1,TNFRSF19,SYTL2,TRAM2,TNS3,ENPP1,SHROOM3,PLEKHF1,TLE1,CDH3,EFNA1,KLF9,FAM84B,MAP3K5,SLC16A5,CAMK2G,IGSF3 |
| 1.251e-04 | -8.99 | response to endoplasmic reticulum stress | biological process | GO:0034976 | 226 | 55 | 16441 | 2455 |
FAF2,HSP90B1,ADD1,SEC61G,DNAJB2,JKAMP,DNAJC3,TRAF2,TMX4,FLOT1,TP53,FBXO2,PDIA5,PDIA3,DNAJB11,FBXO6,DNAJB9,LMNA,PDIA4,CCND1,CALR,SRPX,P4HB,PSMC2,UBE2J1,BAX,TMBIM6,DAB2IP,SELK,STT3B,MYDGF,PDIA6,CTDSP2,TMX1,CTH,GFPT1,UFD1L,SEC61B,ERLEC1,NRBF2,AMFR,PIK3R1,ERO1A,KDELR3,ERP44,TXNDC11,CASP4,VCP,DNAJC10,WIPI1,WFS1,ITPR1,YOD1,MAP3K5,PSMC1 |
| 1.263e-04 | -8.98 | FINETTI_BREAST_CANCER_KINOME_RED | MSigDB lists | FINETTI_BREAST_CANCER_KINOME_RED | 16 | 9 | 17758 | 2588 |
PLK1,PBK,NEK2,PLK4,AURKA,BUB1,AURKB,CDK1,MELK |
| 1.264e-04 | -8.98 | MODULE_2 | MSigDB lists | MODULE_2 | 374 | 81 | 17758 | 2588 |
MYL9,LTBP1,TRIM2,HSPG2,S100A11,THRA,PDGFRL,PLA2G16,EMP2,IER3,CCND1,TGFBR3,SRPX,LMO4,ALDH1A3,BCL6,GOT1,RGS5,NOTCH3,CPE,CYP1B1,MX1,SGCE,MBP,COL6A2,S100A4,ITPR3,ALCAM,DPYSL3,OPTN,WWTR1,MYLK,TLE1,MAOA,RCAN2,MAFF,PCOLCE,CDKN1C,IGFBP6,ENO2,ATP9A,ITGA6,DNAJB2,BLVRB,EPS8,ASAH1,GDF15,TRIB2,SEPP1,FBLN1,DHRS3,TSPAN7,SPP1,CYR61,GPC3,COL6A1,ERBB3,NCAM1,DLX4,FADS2,HES1,MMD,NR4A1,EMP3,FOS,LEPR,CYB5A,RHOB,USP6,IL1R1,TIMP3,ETS2,SCG2,ITGA7,TCEAL4,DTX4,NR4A2,LTBP2,GEM,L1CAM,AHR |
| 1.267e-04 | -8.97 | regulation of innate immune response | biological process | GO:0045088 | 371 | 82 | 16441 | 2455 |
LAMP1,UNC93B1,NLRX1,TRIM5,RPS6KA1,PSME2,XIAP,TAP1,CUL1,PSME1,ITPR2,PRKACA,CALM2,PSMD1,RPS6KA2,PSMC2,PLCG2,DUSP10,NFKB2,SCARA3,LGMN,SMAGP,RASGRP1,RIPK2,TNIP1,ITCH,USP18,ITPR3,DUSP4,SOCS3,FYN,JAK1,PSMD3,NOD2,STAT1,IRF7,PSMC1,PPP2R5D,DDX58,HSP90B1,TAB3,CTSB,HLA-E,SERPINB9,PSMD7,CALM3,PSMD10,HLA-A,IRAK1,PIK3AP1,PAK2,MAPK11,MAPK7,MAP3K7,CNPY3,SYK,PSMA5,PARP9,PLSCR1,PSMB4,MAPKAPK3,CALM1,ELK1,FOS,PSMA4,TXK,BCL10,CTSL,MAPKAPK2,HLA-B,PVRL2,PELI2,NFKBIA,ITPR1,NMI,UBE2D2,NLRC5,ERAP1,IFIH1,RPS6KA3,TMEM173,IRF1 |
| 1.269e-04 | -8.97 | embryonic morphogenesis | biological process | GO:0048598 | 556 | 115 | 16441 | 2455 |
ACVR1,NF2,GRHL2,HSPG2,HOXB7,ST14,RET,TP53,GATA3,OSR2,PRKACA,STIL,EXT2,SETDB2,CTNNB1,IMPAD1,DACT1,LMO4,ELF5,ALDH1A3,SMO,DLG1,TWIST1,ECE1,DVL2,SPEF2,SOD1,ARFRP1,DUSP4,PRKRA,COL12A1,ABR,IRX3,ARHGAP35,SOCS3,SHROOM3,TBX1,PTK7,HOXA9,LRIG1,TRAF3IP1,HDAC1,COBL,PRKAR1A,CTHRC1,TNRC6C,USH1C,RUNX2,CDKN1C,LRP4,SOX9,SDC4,RAB23,TGFBR1,JAG2,NCKAP1,CRABP2,HOXB2,DUSP5,SIX4,FZD6,MECOM,GBX2,VASP,ITGA3,CYR61,GATA2,GPC3,FLRT3,MEGF8,FRAS1,BMP7,COL6A1,BAX,TFAP2A,MAP3K7,WNT3A,NTN1,GFI1,SPRY2,TMED2,DUSP1,MDFI,EPB41L5,CYP26B1,HES1,TGIF1,SALL4,PRICKLE1,SCRIB,KIF20B,COL7A1,NPHP3,BCL10,GNAS,MMP15,TSC1,NCOA3,ETS2,TWSG1,HTT,FGFR2,PLPP3,ITGA7,TBX18,SPINT2,NR4A3,PKD2,EFNA1,ITGAV,SOX8,OSR1,FZD5,SHOX2,RARG |
| 1.270e-04 | -8.97 | ERO1B (endoplasmic reticulum oxidoreductase beta) | protein interactions | 56605 | 15 | 9 | 16036 | 2547 |
P4HB,ERO1A,FBXO2,PDIA3,ERP44,FBXO6,PSMA4,PDIA4,GPX4 |
| 1.275e-04 | -8.97 | SIAE (sialic acid acetylesterase) | protein interactions | 54414 | 50 | 19 | 16036 | 2547 |
CHSY3,MAN2B2,COL18A1,GALNT7,FBXO6,PTGFRN,ARSK,NRP2,KIAA1161,HLA-B,NAAA,TGFBR3,TMEM30A,ERAP1,GDF11,MOXD1,ARSB,CPE,TMEM131 |
| 1.275e-04 | -8.97 | catabolic process | biological process | GO:0009056 | 1809 | 324 | 16441 | 2455 |
GAA,TRIM24,HSPG2,AASS,PNPLA2,DNAJC3,HEXB,FBXO2,CUL1,TRAPPC8,PSME1,CCNB1,PLA2G16,OAT,CALM2,PHYHIP,TYMP,CYP1A1,PSMD1,ZFP36,CYP2S1,PIK3CA,FUT1,PPP1CA,TINAGL1,ACOX2,APOBEC3G,ERAP2,FBXL16,SPATA18,RNF11,CDA,BNIP3L,SLC35C1,MGAM,AGO4,AURKB,CCNF,RNF19B,PNKD,MYOM1,CYP4F3,POR,COL12A1,ENPP1,PLCG1,PTER,MYLK,DHTKD1,MRC2,ALDH6A1,DHPS,CYP2J2,ZNRF3,SLC1A3,ATG4A,GNS,ZCCHC17,RIMS3,RPL39,FBXO7,BDH1,FAM13B,NEK2,FBXL14,PCYOX1,PRKG1,USP1,USP38,ALPK1,STT3B,CTSD,MYLIP,PHKG2,MCCC2,EPHX1,UFD1L,PRODH,CALM1,PYM1,PYGL,PKM,TP53INP2,PSMA4,FBXO10,DCP2,PDE11A,MMP15,NT5C2,FAAH,AURKA,MDH1,XDH,PLA2G4A,PTTG1,MVB12B,PRKACA,NUDT12,CYP39A1,EPM2A,DAB2IP,RNASEH2A,PDE4D,PHKA2,LGMN,NAGA,ATG4D,ENPP4,SEC61B,COL6A2,PFKFB2,SAT1,VPS4B,ATP1B1,CBL,AKR1E2,GABARAPL1,ZMPSTE24,ALDH3B1,ACAD10,WFS1,WWTR1,PNPLA6,PPP1CB,PRIMA1,AREL1,GALK1,HSP90B1,GCAT,BACE1,TRAF2,SDC4,CTSZ,APOBEC3H,PLD2,FBXO6,PNPLA5,WWP2,SGPL1,CAPN2,FUT2,OXCT1,RNF128,CTSC,MGAT1,PTEN,GPC3,FUT8,ADAM15,ECI2,WWP1,CNOT6L,ACBD5,ADAMTS2,PCCB,ALDH2,SHMT1,NUB1,UBE2A,FURIN,FBXO9,BLVRA,RPL12,ACADSB,PLOD2,PRDX3,SLC35B3,PLA2G15,PGM2L1,ERAP1,ARSB,WDR45B,ACOT7,USP16,CASP3,FAF2,AGRN,GNPDA1,CRYM,CPT2,CNOT8,CUL4B,LMCD1,MCCC1,UBE2Z,HDAC6,MAP1LC3B,SDC1,ECI1,MAGOHB,INPP5E,ENTPD4,PSMC2,DDHD2,CYP1B1,PLK1,ITCH,USP18,RNF165,CCBL2,KLK6,CDK1,VCP,TRIM9,PLCH1,NEIL1,HPSE,WIPI1,GLA,PPP2R5D,PSMC1,CAPN1,NR2C2,DNAJB2,ASL,PSMD7,CALM3,CES2,PFKL,COL6A1,AHCY,NCEH1,ZRANB1,ACAD8,GAD1,PLCB2,PSMA5,CYP26B1,USP31,PDE5A,FBXO8,AMDHD1,DHDH,NUDT16,H1F0,COL13A1,PAPD5,CTSA,YOD1,PLD1,COL16A1,RNF146,FBXW5,USP43,UPF3B,PSME2,P2RX7,COL18A1,PATL2,LPIN3,CYP26A1,RAD23A,CYP4F11,KIF14,FABP6,PLCG2,GOT1,ECE1,ETHE1,GM2A,UPF3A,CTH,CHP1,SIRT1,ERLEC1,AKT1,CDC20,DUOX1,DNAJC10,IDE,ALDH5A1,PAFAH1B3,ABHD12,PSMD3,PEX2,MAOA,ADAMTS14,CHMP4B,CYP2U1,RPL22,LTA4H,COL9A3,PINK1,ENO2,CTSB,JKAMP,CIT,HAL,BLVRB,ERI2,PSMD10,COL4A5,NOTUM,DNAJB9,ADORA1,GALNS,UBE2J1,ABCD1,HMGCL,ALDH7A1,FAH,HMMR,PGM1,ADAM17,PSMB4,GUSB,AMFR,OGDHL,COL7A1,RNPEP,USP6,CTSL,FUCA1,CNOT2,DDAH1,CTSV,UBE2D2,ARRB1,GLB1,ACADM,NDFIP1,UBE2C,SAT2,DIS3L |
| 1.276e-04 | -8.97 | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | 184 | 46 | 17758 | 2588 |
GAA,UNC93B1,TMEM184B,S100A11,CD63,PSME2,HLA-E,DNAJC3,BTN3A1,AES,BAIAP3,NTAN1,RSAD1,HLA-A,RPS6KA2,ITGA3,TIMP1,RALGPS2,METTL7A,CDK16,BHLHE41,DRAM1,RPN2,TAGLN2,ETHE1,ITM2C,SMAGP,FAM134C,FAM69A,NAGPA,ITCH,RNF11,LITAF,NPC2,BLVRA,FNDC3A,MAGED2,TAPBP,CASP7,WFS1,NOD2,NXPH4,TLE1,PDXK,FHL1,MAP3K5 |
| 1.276e-04 | -8.97 | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | 184 | 46 | 17758 | 2588 |
UNC93B1,SORT1,REPS2,ASAH1,EFHD2,CTSZ,TMEM170B,GSTP1,ADAMTSL4,TTYH3,BMP2K,MXD1,HDAC9,APLP2,RB1,TM9SF2,DPYSL2,DRAM1,CD9,H2AFY,RP2,MTMR11,NCEH1,PTPRE,CLIP2,DGKG,CCDC88A,PDGFC,CXXC5,MCTP1,PRKAR2B,PCTP,NUDT16,WDR11,PRCP,SECTM1,DGAT2,ZDHHC7,DYSF,PLXND1,GLA,ARSB,SLC31A2,LTA4H,CPPED1,STARD3NL |
| 1.281e-04 | -8.96 | MITSIADES_RESPONSE_TO_APLIDIN_UP | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_UP | 408 | 87 | 17758 | 2588 |
AVPI1,ARMCX3,AASS,TSC22D3,SLC25A13,ETNK1,GMPR,CCNL1,PDGFB,APC2,PHLDA1,MAP1LC3B,TNFSF9,PHF1,CHST2,BTG3,SCNN1A,RPS6KA2,FAM46A,TACC2,FOSB,NFU1,IFIT1,ARMCX6,F2R,SCYL3,CTH,CDKN2AIP,CLCN3,NRBF2,CASP9,RNF11,C3orf52,NFE2L1,EZR,EAF2,STK17B,ARF4,GABARAPL1,IRS2,JAK1,PDLIM3,AREG,ZNF165,IRF7,GLA,ARF6,MAFF,KLF2,PPP1R2,HLA-E,CTSB,DUSP5,H1FX,ICAM1,TIMP1,PPP1R10,CYR61,TMEM62,BHLHE41,MCF2L,COL6A1,MYLIP,GAD1,DUSP1,MOB4,HES1,ELK3,PLSCR1,IFITM3,RAPGEF2,YES1,SRSF5,KDM3A,RHOB,BSDC1,STK17A,GNAS,GALNT3,SLCO4A1,NFKBIA,NR4A3,ATP1B3,GEM,JARID2,IRF1,ABCG1 |
| 1.284e-04 | -8.96 | cellular glucan metabolic process | biological process | GO:0006073 | 57 | 20 | 16441 | 2455 |
PGM1,GAA,PPP1R2,UGP2,AKT1,CALM1,CALM3,PYGL,MGAM,EPM2A,PER2,CALM2,PRKAG2,IL6ST,GYS1,PGM2L1,PPP1CB,PPP1CA,PHKA2,PHKG2 |
| 1.284e-04 | -8.96 | glucan metabolic process | biological process | GO:0044042 | 57 | 20 | 16441 | 2455 |
PGM1,GAA,PPP1R2,UGP2,AKT1,CALM1,CALM3,PYGL,MGAM,EPM2A,PER2,CALM2,PRKAG2,IL6ST,GYS1,PGM2L1,PPP1CB,PPP1CA,PHKA2,PHKG2 |
| 1.298e-04 | -8.95 | antigen processing and presentation of endogenous peptide antigen via MHC class I | biological process | GO:0019885 | 10 | 7 | 16441 | 2455 |
ERAP1,HLA-B,TAPBP,HLA-C,ERAP2,HLA-A,TAP1 |
| 1.298e-04 | -8.95 | DOUGLAS_BMI1_TARGETS_DN | MSigDB lists | DOUGLAS_BMI1_TARGETS_DN | 302 | 68 | 17758 | 2588 |
UNKL,FAM199X,GNPDA1,ETNK1,TDRKH,FAM91A1,ELMOD2,EPDR1,WEE1,SESN3,SP100,ARL1,ZDHHC12,IFIT1,ACSL4,OAS3,NFKB2,IL1RAP,TMBIM1,SOAT1,CLCN3,APOBEC3D,SLC39A8,PANK1,TMEM144,ATP10D,LCP1,OPTN,ENPP1,TMEM164,RBM47,STAT6,STAT1,NFKBIZ,PLSCR4,CPEB4,BVES,JKAMP,BTN3A1,HERC6,ICAM1,FZD6,PARM1,TMEM63A,M6PR,SGK1,ACTA2,CTSD,FAM134C,SUN2,TACC1,RAPGEF2,PIP4K2C,CALCRL,VEZT,BCL2L13,IFIT3,RASA1,DCP2,PITX2,H1F0,RAP2C,ARAP1,PGM2L1,CLIP4,FGD6,SEMA3A,IFI6 |
| 1.302e-04 | -8.95 | HALLMARK_TGF_BETA_SIGNALING | MSigDB lists | HALLMARK_TGF_BETA_SIGNALING | 54 | 19 | 17758 | 2588 |
TGIF1,ACVR1,RHOA,CDKN1C,XIAP,FURIN,TGFBR1,SLC20A1,BCAR3,BMP2,FNTA,CDH1,CTNNB1,WWTR1,RAB31,HDAC1,LTBP2,PPP1CA,MAP3K7 |
| 1.302e-04 | -8.95 | WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 | MSigDB lists | WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 | 54 | 19 | 17758 | 2588 |
DLGAP5,ZNF84,ASPM,PBK,RACGAP1,AURKB,ANLN,CCNB1,CDK1,FANCI,TCN2,TOP2A,UBE2T,CYR61,PRC1,AURKA,BUB1,KNTC1,UBE2C |
| 1.308e-04 | -8.94 | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 179 | 45 | 17758 | 2588 |
CCNE2,RECQL,CDS2,MRC2,TXN,TSPAN15,TSC22D3,EPS8,CTSZ,BCL2L1,DSE,BARD1,LMNA,UHRF1BP1L,TFAP2E,GNS,CD109,TAF1B,KCNN4,DPYSL2,CENPJ,TMEM62,N4BP3,FBXO7,PAPSS1,CNNM4,TNFRSF12A,HYLS1,ECE1,F2R,TMX1,ATP2B1,GCNT1,NEK4,CEP89,SNTB2,SAT1,PIK3R1,RUNX3,TP53INP2,FRMD4B,MAPKAPK2,SLCO4A1,PITPNA,CENPE |
| 1.308e-04 | -8.94 | GSE12366_GC_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_GC_VS_NAIVE_BCELL_DN | 179 | 45 | 17758 | 2588 |
KLF2,SLC25A24,CD63,CAST,HEXB,DGKA,SELL,BTN3A1,IL13RA1,NOTCH2,CAMK1D,PATL2,HERC6,HLA-A,DTX3L,CD46,SNX18,OPN3,FXYD5,SLC39A10,PLCB2,DUSP1,PARP9,HES1,ARAP2,CD55,IFITM3,PLEKHO1,GYLTL1B,BTN3A2,EMP3,ROR1,ESYT1,FNDC3A,CD83,C19orf66,RIN3,STAT1,ABCB1,FAM117A,NR4A2,CTNND1,PLOD3,SLC25A30,CBX7 |
| 1.309e-04 | -8.94 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | 471 | 98 | 17758 | 2588 |
ACVR1,TRIM2,PNISR,IBTK,SUZ12,SLC25A13,EPHA4,NDC80,RGS20,ARFGEF1,CUL1,TRAPPC8,PJA2,BARD1,STIL,ZFYVE9,APPBP2,CTGF,FRYL,KIF14,ATP13A3,MYBL1,TIPARP,TIAM1,IL1RAP,MGAT5,SMARCA2,CENPA,STAU2,CDYL,LHFPL2,TRAM2,FYN,TDRD7,TLE1,NRG1,STARD13,WASF3,CDS2,CDK17,PPP1R12A,FAM169A,NUAK1,ARHGEF7,EPS8,KIF23,PBX3,RAB6A,PHLPP1,PPP2R3A,HMGXB4,CKAP5,TOP2A,SNX13,RB1,DOPEY2,CYR61,FUT8,GTF2F2,DAPK1,MSH2,PRKCI,LIMCH1,PIKFYVE,RPGR,NCOA2,ATP2B1,DUSP1,SOCS5,CASK,NR3C1,RAPGEF2,KIF20B,KIAA1109,FNDC3A,KIF11,NFIB,EGFR,RASA1,NMT2,MAP1B,USP6,BCAR3,CNOT2,NCOA3,SWAP70,PHLPP2,UBE2D2,RYK,PKD2,STK39,CENPE,ZMIZ1,AFAP1,MELK,KLF7,JARID2,TMEM131 |
| 1.322e-04 | -8.93 | Signaling by Leptin | REACTOME pathways | R-HSA-2586552 | 236 | 57 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,LEPR,PSMA4,RASA1,EGFR,SOCS3,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.326e-04 | -8.93 | blood vessel development | biological process | GO:0001568 | 438 | 94 | 16441 | 2455 |
ACVR1,PAX6,HSPG2,EPAS1,FOXM1,COL18A1,IL18,EGR3,VASH1,PDGFB,PDGFA,TYMP,NOV,CTNNB1,CTGF,PIK3CA,SMO,DAB2IP,EPHB4,NOTCH3,TIPARP,LOXL1,CYP1B1,MAP3K3,SIRT1,AKT1,FZD4,SAT1,HTATIP2,LOXL2,EDNRA,SOCS3,PGF,PTGS2,HS6ST1,PTPRJ,HPSE,TBX1,MYLK,PNPLA6,KLF5,PLXND1,UNC5B,E2F8,NKX3-1,ADGRG1,CCM2,TGFBR1,ETS1,SRPX2,NRP2,GBX2,SGPL1,E2F7,PDCD10,ITGB8,PTEN,CYR61,GPC3,BAX,ADAM15,ACTA2,TNFRSF12A,MYDGF,MAP3K7,SYK,TMED2,HES1,ELK3,NR4A1,RAPGEF2,CALCRL,EPHA1,RHOB,RASA1,GPLD1,ARHGAP24,ACVRL1,SCG2,FGFR2,PRCP,ITGA7,PLPP3,FGF18,ERAP1,EGFL7,PKD2,HOXB13,EFNA1,ITGAV,FZD5,ZMIZ1,OSR1,AHR |
| 1.327e-04 | -8.93 | breast-other-papilloma | COSMIC cancer mutations | breast-other-papilloma | 30 | 13 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,GNA11,EGFR |
| 1.329e-04 | -8.93 | KOYAMA_SEMA3B_TARGETS_UP | MSigDB lists | KOYAMA_SEMA3B_TARGETS_UP | 264 | 61 | 17758 | 2588 |
KIF3C,CTHRC1,PAX6,IGFBP6,MCOLN3,PKP2,GDF15,CRABP2,LGALS3BP,SIRPA,PDGFA,NOV,CTGF,SRPX,SP100,RNF128,PTEN,CTSC,KCNN4,PAQR5,FRAS1,TOX2,AIM1,AOX1,ARVCF,ERCC2,ACOX2,MINPP1,ETHE1,DLG3,LOXL1,SEMA3B,WBP5,SUN2,PCGF5,HMGN5,SH3BGRL,PLAUR,CASP9,HTATIP2,ARHGDIB,CYFIP2,ITPR3,TCEAL8,ANTXR1,ZNF618,STEAP1,MAP1B,DDAH1,SWAP70,SERPINA1,PVRL2,AXL,PLEKHG1,SERPINI1,LTBP2,DMWD,FBXO27,SLC31A2,SLC27A3,RPS6KA3 |
| 1.357e-04 | -8.91 | PID_CDC42_REG_PATHWAY | MSigDB lists | PID_CDC42_REG_PATHWAY | 30 | 13 | 17758 | 2588 |
BCAR3,PLCG1,MCF2L,ARHGEF7,RALBP1,SPATA13,RACGAP1,DOCK11,ARHGEF9,DOCK9,FGD1,FARP2,NGEF |
| 1.358e-04 | -8.90 | negative regulation of transferase activity | biological process | GO:0051348 | 328 | 74 | 16441 | 2455 |
CASP3,SPRED1,NF2,IBTK,DNAJC3,PSME2,PSME1,TP73,CDKN2C,PSMD1,RGS3,PSMC2,DUSP10,CDKN1B,DAB2IP,CDKN2D,CHP1,PLK1,SIRT1,AKT1,CDC20,COX11,PRKAR2B,PIF1,DUSP4,SOCS3,IRS2,PTPRJ,CAMK2N2,PPP2R5A,PSMD3,CORO1C,LIMK1,STK38,WWTR1,RGS14,HSPB1,PSMC1,PRKAR1A,CDKN1C,UBASH3B,PSMD7,PSMD10,PKN1,TRIB2,GSTP1,DUSP5,TFAP4,RB1,IGF1R,PTEN,BMP7,FBXO7,PAK2,SORL1,H2AFY,BUB1,HEXIM2,SPRY2,PSMA5,DUSP1,SOCS5,PSMB4,EPHA1,ILK,PSMA4,MAPK8IP1,CDK5RAP1,PRKAG2,PRDX3,UBE2C,HIPK3,PKIA,DRD1 |
| 1.367e-04 | -8.90 | MODULE_198 | MSigDB lists | MODULE_198 | 297 | 67 | 17758 | 2588 |
CCNE2,PAX6,FOXM1,PTTG1,NDC80,CCNO,KIF2C,CCNB1,BARD1,PHLDA1,RAD23A,CDKN2C,APLP2,WEE1,PCNA,HSF2,CCNA2,KIF22,MYT1,NEK4,PLK1,CENPA,AKT1,GTF2A2,CDC25C,CDK1,PRIM1,MAP2,STK38,STAT1,TLE1,HDAC1,XRCC3,PPP2R5D,CBX4,SOX9,PSMD10,KIF23,DUSP5,TOP2A,GTF2F2,TFAP2A,MSH2,NEK2,BUB1,KNTC1,RFX5,GFI1,TGIF1,ZWINT,PAPD7,BCL9,UBE2A,MYBL2,RUNX3,FOS,PSMA4,DDX23,HNRNPH2,DCK,E2F1,CENPE,CBX5,CCNB2,ESPL1,CSRP2,RAD21 |
| 1.373e-04 | -8.89 | Aurora B signaling | Pathway Interaction DB | aurora_b_pathway | 39 | 19 | 2227 | 480 |
RHOA,CENPA,KIF20A,TACC1,KLHL13,CDCA8,NDC80,KIF23,RACGAP1,KIF2C,AURKB,RASA1,MYLK,AURKA,BUB1,CBX5,SGOL1,PPP2R5D,SMC4 |
| 1.379e-04 | -8.89 | Diseases of signal transduction | REACTOME pathways | R-HSA-5663202 | 268 | 63 | 8202 | 1235 |
CCNC,TRIM24,PSME2,HDAC11,PSMD7,CUL1,PSMD10,ERBB2,NRG2,TGFBR1,PSME1,JAG2,HDAC6,PDGFB,KREMEN1,FGF19,ZFYVE9,FZD6,HDAC9,PDGFA,PSMD1,CTNNB1,CNTRL,PSMC2,PIK3CA,CDKN1B,ERBB3,PIK3CD,WNT3A,FGFR1OP2,PSMA5,HES1,ADAM17,ERLEC1,KREMEN2,AKT1,PSMB4,FZD4,NR4A1,AMER1,CASP9,PIK3R1,MAML2,CBL,NEURL1B,PSMA4,EGFR,VCP,IRS2,PLCG1,FYN,PPP2R5A,FGFR2,PSMD3,FGF18,STAT1,HDAC1,NRG1,FZD5,PPP2R5D,PSMC1,GAB1,CTBP1 |
| 1.380e-04 | -8.89 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP | 195 | 48 | 17758 | 2588 |
NFKBIE,TSC22D3,CTSB,FAM134A,PDIA3,TESK2,PKN1,DUSP5,PDIA4,AKIRIN1,NAPG,TYMP,PTEN,DPYSL2,PAK2,DUSP10,AHCY,OSTF1,KLF9,NPTN,NFKB2,TMED2,CKAP4,AGPS,LAP3,PIK3R1,RNF11,UBAC1,RNF19B,STK17B,UAP1,HNRNPH2,NFKBIA,RAP2C,PPP1CB,NR4A2,KLF11,SPCS3,ATP1B3,PLIN3,REEP4,RTN3,TOB1,MAFF,ATMIN,SRSF9,IRF1,RRAGD |
| 1.380e-04 | -8.89 | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | 195 | 48 | 17758 | 2588 |
TXN,NFKBIE,NQO1,S100A11,CD63,ARHGEF11,CTSB,DCAF7,FTH1,MGST2,DSE,M6PR,SNX13,ATP6V0B,C7orf49,SLC16A6,PLCG2,CST3,DAPK1,H2AFY,TAX1BP3,NPTN,TFG,TIAM1,NAGA,SYK,LAMP2,SOAT1,GCA,LAP3,RAPGEF2,VAMP3,SLC11A2,ATP1B1,IDH1,CD83,KLHL2,RCBTB2,GDE1,HTT,CORO1C,PNPLA6,RAB31,RAB11FIP1,MDH1,PLIN3,ZMIZ1,SLC31A2 |
| 1.380e-04 | -8.89 | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP | 195 | 48 | 17758 | 2588 |
RMND5A,CCNI,AVPI1,PAPSS2,EPAS1,GNPDA1,NUAK1,GGA1,CTDSPL,DGKA,ABCG2,NDRG2,RASGRP3,CRABP2,OAT,MERTK,BMP2K,RPS6KA2,RIMS3,COL6A1,FUT8,PASK,OPN3,CD9,TIAM1,SLC16A5,NUP85,RIMS2,CDKN2AIP,PDGFC,MMD,BNIP3L,ROR1,KDM3A,SESN1,FOS,MYOM1,RASA1,IL1R1,MOSPD3,SWAP70,VSIG10,MAPK13,PLXND1,LTBP2,ZMIZ1,LTA4H,RTN3 |
| 1.380e-04 | -8.89 | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDM_UP | 195 | 48 | 17758 | 2588 |
TM2D2,TTC39B,NFKBIE,CHCHD7,HEBP1,TSC22D3,LRP4,HEXB,DGKA,ARFGEF1,NUF2,PLA2G16,BARD1,FLII,PQLC2,CNTRL,KLF3,TPST1,SLC44A2,SNX16,CTDSP2,RBMS2,GCA,HES1,PTPN18,TEP1,BNIP3L,UTRN,HMG20B,TNS1,UBAC1,ESYT1,ILK,RNPEP,MYOM1,SP4,ATP13A2,HLA-B,FYN,PPP2R4,FAM3C,ABCB1,STK39,GLA,RGS14,HSPB1,MAD2L1BP,ABCG1 |
| 1.399e-04 | -8.87 | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | MSigDB lists | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | 409 | 87 | 17758 | 2588 |
LMO7,ACACB,SORBS1,PAPSS2,IL15RA,DLGAP5,NQO1,ATP8A1,TSC22D3,SOD2,COL18A1,NDRG2,CCNL1,PHLDA1,EMP2,PER2,TGFBR3,RPS6KA2,SRPX,METTL7A,ZFP36,MITF,KCNS3,RGS5,SEMA3G,MYBL1,CPE,CYP1B1,OLFML2A,MX1,ING1,MARK1,CAPN6,ARHGDIB,PRKAR2B,LOXL2,MCFD2,ALCAM,CDK1,HLF,POPDC3,MAOA,KLF11,CDKN1C,SERPINE2,GDF15,COL4A5,SEPP1,ANO1,SRPX2,RND1,TOP2A,BMP2,GPC3,KIF13B,BAX,CD9,LIMCH1,KLF9,MOXD1,MYLIP,SPRY2,IGSF3,DUSP1,CYP26B1,GFPT1,ASPM,PIK3R1,FHL2,SPTLC2,NFIB,EGFR,RHOB,FRMD4B,CD83,DDAH1,ETS2,NFKBIA,MATN2,FAM117A,CLMN,ERAP1,GEM,PER3,IFIH1,MELK,IRF1 |
| 1.415e-04 | -8.86 | activation of innate immune response | biological process | GO:0002218 | 248 | 59 | 16441 | 2455 |
DDX58,UNC93B1,HSP90B1,TRIM5,TAB3,RPS6KA1,CTSB,PSME2,PSMD7,CALM3,CUL1,PSMD10,PSME1,ITPR2,PRKACA,CALM2,PSMD1,RPS6KA2,IRAK1,PIK3AP1,PSMC2,PLCG2,PAK2,MAPK11,NFKB2,MAP3K7,SCARA3,LGMN,MAPK7,CNPY3,SYK,PSMA5,RIPK2,TNIP1,PSMB4,MAPKAPK3,ITCH,CALM1,ITPR3,DUSP4,ELK1,FOS,PSMA4,BCL10,MAPKAPK2,CTSL,FYN,PELI2,PSMD3,ITPR1,NFKBIA,UBE2D2,NOD2,IRF7,IFIH1,PSMC1,PPP2R5D,RPS6KA3,TMEM173 |
| 1.419e-04 | -8.86 | cellular lipid metabolic process | biological process | GO:0044255 | 907 | 175 | 16441 | 2455 |
ACACB,UGT8,HSPG2,AGRN,TMEM86B,CPT2,PNPLA2,HEXB,EPHX4,PHOSPHO1,TEX2,NANS,PLA2G16,CDIPT,PIGL,SDC1,ECI1,HELZ2,INPP5E,CYP1A1,CTGF,GRHL1,CYP2S1,IMPAD1,ALDH1A3,SLC44A1,RDH14,SERINC2,PIK3CA,PIK3CD,ACOX2,PPP1CA,TECR,CERS2,CYP1B1,SLC35C1,PRKAR2B,SLC17A5,IDH1,CYP4F3,POR,SGPP1,SLC44A3,KDSR,PLCG1,PI4K2B,AGPAT2,DOLPP1,ADIPOR1,PIK3C2B,GLA,CHPT1,PRKAA2,FAM213B,INPPL1,CYP2J2,TMEM55B,ELOVL7,PRKAA1,ASAH1,ISYNA1,B4GALT4,DHRS3,PGAP1,B4GALNT1,OCRL,BDH1,PIKFYVE,FAR2,ACAD8,PLCB2,ALDH3A2,ABCC1,CYP26B1,PIGC,GFPT1,FADS2,PQLC3,LPGAT1,FHL2,PIP4K2C,SPTLC2,MAPKAPK2,PRKAG2,UAP1,FA2H,FAAH,PLPP3,DGAT2,CTSA,SAMD8,ALG2,PLD1,PLA2G4A,MTM1,INPP5D,ETNK1,P2RX7,MGST2,LPIN3,PRKACA,CYP26A1,PER2,CDS1,PLCG2,FABP6,ACSL4,FAR1,NAGA,GM2A,GPX4,SIRT1,SOAT1,AGPS,PTGS2,ALDH3B1,ALDH5A1,ABHD12,ACAD10,PEX2,INPP4B,PNPLA6,PPP1CB,SLC27A1,CYP2U1,LTA4H,SLC27A3,ST3GAL1,ABCA1,KDELC2,CMAS,CDS2,SCD5,GNE,SDC4,PLD2,CRABP2,PLPPR4,SGPL1,ITGB8,OXCT1,SLC27A6,PTEN,ARSG,A4GALT,GPC3,ALG13,BAX,SLC44A2,ECI2,HMGCL,ABCD1,SYK,SLC35A1,NCOA2,MYO5A,PCCB,PLSCR1,PLAUR,PIK3R1,ELOVL3,PPARA,RNPEP,ARSK,CPTP,DGKE,GPLD1,ACADSB,DBI,PLA2G15,GLB1,ACADM,ARSB,PTGES,ACOT7 |
| 1.422e-04 | -8.86 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | 190 | 47 | 17758 | 2588 |
NFKBIE,IL15RA,IL15,FOXM1,ATP8A1,CDCA3,TAP1,SOD2,BTN3A1,IL27RA,CD274,GALM,AIFM2,ICAM1,SCML1,ASPHD2,M6PR,SGPL1,MAGOHB,DTX3L,TYMP,DAZAP1,FBXL14,DRAM1,RFX5,MINPP1,NFKB2,RASGEF1A,ETV7,C9orf72,PSMA5,PPIF,NFE2L3,CENPA,LAP3,MICB,FOXJ2,KBTBD8,PNKD,ADRBK2,TYSND1,SOCS3,SLC2A6,STAT1,CCDC69,ERAP1,IRF1 |
| 1.422e-04 | -8.86 | GSE17721_POLYIC_VS_CPG_8H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_8H_BMDM_UP | 190 | 47 | 17758 | 2588 |
CCNI,TM2D2,NDRG1,INPP5D,IQGAP1,ARHGEF7,RASA2,PTTG1,DGKA,CD274,MGST2,CAMK1D,LPIN3,COMMD5,SESN3,BDH1,KLF3,TPST1,BCL6,SORL1,SGK1,ESPN,TMEM8A,RBMS2,EPHX1,B9D2,CASP9,UTRN,DBR1,UBAC1,SP4,ATP13A2,FUCA1,ENDOD1,HLA-B,TAPBP,FYN,PRCP,PLK2,SH3BP4,HDAC1,FZD5,NCAPG2,PRR15,ANXA11,CPPED1,ABCG1 |
| 1.422e-04 | -8.86 | V$EGR2_01 | MSigDB lists | V$EGR2_01 | 190 | 47 | 17758 | 2588 |
DOC2A,CMAS,SCN5A,PCOLCE,MRC2,UBASH3B,THRA,DCAF7,RHBDL3,EGR3,TP53I11,VASH1,BAHD1,PDGFB,SPTB,XPR1,HDAC9,WWP2,CDKN2C,TFAP4,RALGPS2,ITGB8,SH3BP1,WDR44,RRBP1,BCL6,SMYD5,ETV4,C9orf72,DVL2,MAP3K3,SIRT1,SUN2,ATL1,KREMEN2,HMG20B,KIF1C,PRRC1,MAN2A2,NAB2,ITPR1,KLF5,ATP6V1C1,OSR1,ITPKA,NRGN,PTGES |
| 1.422e-04 | -8.86 | GTPase binding | molecular function | GO:0051020 | 265 | 62 | 16491 | 2452 |
EXPH5,PIFO,RALBP1,RUSC2,NDRG1,IQGAP1,EPS8,RASGRP3,SYTL4,NCKAP1,PKN1,MICALL2,DOCK11,CCDC64B,RIC1,GNB2,ARHGEF16,SYTL2,RABGGTA,PAK6,ACAP2,MLPH,NOXA1,LLGL2,CDKL5,OCRL,PAK2,RANBP1,EXOC8,TNPO2,SORL1,IQGAP3,MYRIP,C9orf72,SYTL3,MYO5A,RIMS2,MYO5B,DOCK4,SOD1,DIAPH2,STRADB,RANBP9,RASA1,LCP1,OPTN,PEX5,RAB11FIP2,CORO1C,RIN3,SH3BP4,RAB11FIP1,TRIOBP,MAP3K11,FGD6,ARHGAP4,ITPKA,RAP1GAP,ABCA1,DOCK9,EHD1,FGD1 |
| 1.423e-04 | -8.86 | peritoneum-mesothelioma | COSMIC cancer mutations | peritoneum-mesothelioma | 46 | 17 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,JAK3 |
| 1.423e-04 | -8.86 | endometrium-carcinoma | COSMIC cancer mutations | endometrium-carcinoma | 46 | 17 | 17775 | 2585 |
AKT1,RET,PIK3R1,TP53,ERBB2,FLT3,EGFR,RB1,CDH1,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,MSH2,MSH6,PRKAR1A |
| 1.426e-04 | -8.86 | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | MSigDB lists | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | 81 | 25 | 17758 | 2588 |
PPIF,CASP3,PCCB,ZWINT,SERPINE2,DLGAP5,BLVRB,CDC20,RACGAP1,NUSAP1,PRKAR2B,KIF11,CDK1,LEPR,LMNA,ITGA2B,SAC3D1,APOBEC3B,TOP2A,CA2,AMMECR1,PRC1,MINPP1,CCNB2,MELK |
| 1.428e-04 | -8.85 | microtubule-based movement | biological process | GO:0007018 | 196 | 49 | 16441 | 2455 |
DYNLRB1,KIF3C,DLGAP5,AK7,KLC2,KIF23,RACGAP1,KIF2C,RAB6A,APBA1,KIF26A,DNAH3,IFT27,KTN1,SSX2IP,TTC21B,KIF5B,LRRC6,DNAH6,KIF13B,KIF14,KLC3,KIF22,RPGR,TTLL1,RASGRP1,DNAI1,SOD1,LCA5,KIFC2,CELSR2,KIF20A,CFAP46,UXT,SPA17,KIF1C,KIF13A,KIF20B,NPHP3,KIF11,MAP1B,HTT,WDR19,TRAF3IP1,SSNA1,CENPE,KIF12,NDE1,COPG1 |
| 1.434e-04 | -8.85 | kinesin complex | cellular component | GO:0005871 | 54 | 19 | 17570 | 2579 |
KIF3C,KIFC2,KIF20A,KLC2,KIF23,KIF1C,KIF20B,KIF13A,KIF2C,KIF11,KIF26A,KIF5B,KIF13B,KIF14,KLC3,KIF22,CENPE,NDE1,KIF12 |
| 1.458e-04 | -8.83 | QI_PLASMACYTOMA_UP | MSigDB lists | QI_PLASMACYTOMA_UP | 254 | 59 | 17758 | 2588 |
CASP3,LASP1,NFKBIE,RPS6KA1,UBASH3B,CD82,ITGA6,IL18,IL27RA,PDGFB,FLT3,IL17RB,RB1,ZYX,RAC2,VASP,SP100,RABEP2,SH3BP1,CD22,CAPG,TMBIM6,IRF2,TRIM21,RP2,RAG1,NTN1,SNX10,S100A13,ARAP2,HPS3,PTPN18,PLSCR1,PLEKHO1,SLC11A2,ARHGDIB,CD40,STK17B,CASP4,LCP1,FRMD4B,FAS,BTG1,SWAP70,CASP7,TJP3,LIMK1,AXL,NFKBIA,UBE2D2,ARAP1,ARRB1,STK39,ICOSLG,PTGES,ANXA11,CAPN1,IRF1,EHD1 |
| 1.459e-04 | -8.83 | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | 134 | 36 | 17758 | 2588 |
RPS6KA1,CALM3,ITPR2,PHLPP1,PRKACA,CALM2,RPS6KA2,ADRBK1,PTEN,SHC3,RALB,DNM2,PIK3CA,CDKN1B,MAPK11,MAPK7,RHOA,AKT1,MAPKAPK3,NR4A1,PIK3R1,CALM1,CASP9,PRKAR2B,DUSP4,ELK1,ITPR3,CDK1,IRS2,MAPKAPK2,PLCG1,MAPK13,PPP2R5D,RPS6KA3,MAPK12,PRKAR1A |
| 1.461e-04 | -8.83 | WILCOX_RESPONSE_TO_PROGESTERONE_UP | MSigDB lists | WILCOX_RESPONSE_TO_PROGESTERONE_UP | 139 | 37 | 17758 | 2588 |
PLA2G4A,ARHGEF3,DLGAP5,HJURP,NDC80,HMGN3,SAMD9,CCNB1,CENPN,FANCI,DNAJB9,TOP2A,CDKN2C,KIAA0895,MDM1,METTL7A,PRC1,SGK1,DLX4,HMMR,CDKN2AIP,FADS2,SHMT1,KIF20A,LGALS8,ASPM,PBK,CDC20,NUSAP1,IDH1,CDK1,KDSR,AREG,KLF5,CCNB2,TLL2,ABCG1 |
| 1.461e-04 | -8.83 | BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP | MSigDB lists | BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP | 46 | 17 | 17758 | 2588 |
EXPH5,MLEC,TXN,DLGAP5,ASPM,NUSAP1,MORF4L2,OAT,DENND2D,TOP2A,DLG1,CDKN1B,CENPE,TAGLN2,TIAM1,UBE2C,APOBEC3G |
| 1.461e-04 | -8.83 | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN | MSigDB lists | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN | 46 | 17 | 17758 | 2588 |
SLC35D2,SOD1,PPP1R2,LYRM1,TMX4,PARP4,PBX3,TRAPPC8,TGOLN2,GTF3A,GLO1,CDK14,MAGED2,MYLK,UBE2D2,CBX7,JARID2 |
| 1.462e-04 | -8.83 | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN | 185 | 46 | 17758 | 2588 |
PRKAA2,SERPINE2,EPAS1,ST14,UBASH3B,NDRG1,ARMC7,ASAH1,KCTD12,ADAMTSL4,EPDR1,TMEM63A,RCN1,CD109,ATP6V0B,RNF128,FAM160A2,RGS3,MGAT4A,CAPG,ADAM15,GFI1,FLOT2,RASGRP1,TMBIM1,HP1BP3,LOC81691,SMARCA2,CITED4,TESK1,LPGAT1,PLEKHO1,TEP1,PTGER4,GGH,YES1,TP53INP2,STK17B,PLCG1,BTG1,GNPTAB,CSF1,ABCB1,GDF11,LRRK1,TMEM159 |
| 1.465e-04 | -8.83 | CTNNB1 (catenin (cadherin-associated protein), beta 1) | protein interactions | 1499 | 315 | 75 | 16036 | 2547 |
CASP3,NF2,EPAS1,GRIK2,TRIP10,NDRG1,CD82,IQGAP1,PKP2,CUL1,ERBB2,HDAC6,APC2,ZFYVE9,PICK1,CCND1,RNF220,CCNA2,CDH1,MITF,BCL6,CDH3,TAX1BP3,ASH2L,DVL2,PLK1,SIRT1,AKT1,PTPRU,EZR,ERBB2IP,PYGO1,CBL,JADE1,PTGS2,FYN,PTPRJ,HDAC1,TLE1,KLF5,CTNND1,HERC5,TGFBR1,LMNA,CTNNBIP1,TOP2A,PTEN,NEK2,TFAP2A,SGK1,IGFBP2,NCOA2,DLGAP1,NR4A1,RAPGEF2,BCL9,PIK3R1,AMER1,FHL2,GRIN1,WHSC1,VEZT,ILK,CDK5R1,EGFR,FAS,PITX2,PTPRF,HTT,RYK,GRIN2D,CTBP1,TOB1,AHR,ZBTB33 |
| 1.467e-04 | -8.83 | SIG_CD40PATHWAYMAP | MSigDB lists | SIG_CD40PATHWAYMAP | 34 | 14 | 17758 | 2588 |
NFKBIE,TRAF2,NFKBIA,PIK3R1,PIK3CA,MAPK11,MAPK13,PIK3CD,CD40,NFKB2,TRAF5,MAPK8IP1,DUSP1,MAPK12 |
| 1.480e-04 | -8.82 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 3776 | 620 | 17775 | 2585 |
DOC2A,TRIM24,IBTK,AASS,SLC25A13,DNAJC3,RET,CACNA2D2,NRG2,SNX9,GRM5,CALM2,CDKN2C,DAPK2,PSMD1,ARHGAP42,DNAH6,PIK3CD,TIAM1,IL10RB,CPE,ERAP2,NEK4,SPEF2,SH3BGRL,CDA,TFAP2C,PRKAR2B,LOXL2,PPP1R14C,MYOM1,GINS4,COL12A1,BOLA3,PLCG1,WDR11,LIMK1,CELF5,MYLK,NOD2,HDAC1,STARD13,PDPR,GAB1,ZNF720,FAM169A,SLC36A4,GPSM2,MERTK,ATG4A,MARCH8,FRY,FAM189A1,RIMS3,FBXO7,MAP3K9,SLAIN2,CADPS2,USP38,STT3B,NCAM1,MOXD1,MYLIP,DGKG,NUP85,MCCC2,STAT4,MYBL2,KIF20B,DPYSL4,PCTP,DCP2,CYB5A,STK17A,DHX32,PTPRF,CACHD1,NCOA3,NAAA,HTT,ITPR1,DGAT2,DYSF,XDH,EGLN1,DOCK9,WDR63,GRHL2,PAPSS2,ACTR8,RHBDL3,APOO,ETNK1,PKP2,TESK2,FAM91A1,APC2,REPS1,KIAA1147,ZNF385B,APPBP2,CDS1,UHRF1BP1L,RNF220,CDH1,RNF169,SCN3A,AGPS,PTPN9,SYNE2,VPS4B,CDCA2,RAB38,TANC1,IRS2,SPIN3,CCNB3,SHROOM3,CDK19,SIPA1L1,WWTR1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,FAM189A2,PARP14,BACE1,HABP4,SDC4,ANO9,PKN1,PLPPR4,ETS1,ICAM1,NEO1,PDIA4,ZFX,PDCD10,SLC27A6,ANKS1B,CTSC,FAM20B,KLC3,WWP1,NPTXR,ADAMTS2,PLSCR1,CTNNAL1,TACC1,RAPGEF2,PIK3R1,EIF5A2,PLEKHA7,RAB3IP,SNTB1,ABLIM2,TXK,CNTNAP1,BTG1,RPL12,PROM1,PLOD2,SYT7,NR1D2,ZFP30,PPM1H,ITGAV,DCBLD1,TLL2,BCAM,AGRN,EPAS1,EPHA4,CUL4B,LMCD1,ITPR2,SDC1,PIGL,NUP210,TM9SF2,SHC3,PAPSS1,MITF,DUSP10,RGS5,ANO4,TLN2,MYBL1,TRAM1,S100A13,SMAGP,ZNF462,THRB,MCTP1,PTPN18,KCNIP3,CELSR2,C12orf65,ERP44,ANLN,IDH1,DPYSL3,TRAM2,KLF12,RAB11FIP1,PIK3C2B,EPB41L4A,GLCCI1,TC2N,HS6ST3,RRAGD,FXYD3,RAB6A,CNTNAP2,NCKAP1,B4GALT4,DOCK11,PGAP1,SSX2IP,MYO5C,TNS3,RB1,VASP,IGF1R,FRAS1,MDFIC,PIM1,WNT3A,NTN1,ABCC1,CHSY3,WDR72,PCDH1,CORO2A,SPATA13,IFIT3,BCL2L13,UNC45B,ANKRD29,P4HA3,PLD1,SEMA3A,USP43,KCNAB3,CTDSPL,TMX4,XYLT1,TP53,RHPN2,ERBB2,P2RX7,STIL,PER2,CDK14,TTC21B,TACC2,LMO4,PPME1,PLCG2,BCL6,CDH3,GLB1L2,NOTCH3,FAR1,SULF2,CLCN3,TMTC1,MBP,AKT1,DAG1,IDE,ABHD12,PTK7,ADAMTS14,MAOA,CHMP4B,EFNA5,NDST3,CMTM4,FAM134B,BIN1,GOLIM4,CDH22,TRAPPC10,SCD5,GNAL,MCTP2,GABRG2,JAG2,DSE,SLC9A2,NRP2,FZD6,SH2D4A,ZDHHC21,CD109,CEP97,MAGEE1,UBE2J1,SGK1,BUB1,FAM134C,IGDCC4,NFE2L3,DLGAP1,RHOA,NR3C1,MAML2,PELI3,FNDC3A,TXNDC11,DGKE,CD83,BCL10,DDAH1,BANK1,FAT4,SH3BGRL2,TBC1D4,PTGES,HIPK3,ARHGEF4,FAM171B,SLC35D2,PPP4R4,HSPG2,LGR4,VANGL1,FAM129B,ATP8A1,PDGFRL,VASH1,TYMP,SESN3,ZNF823,STIM1,ELMO2,SERINC2,PIK3CA,ATRNL1,ORAI2,LOC81691,SNTB2,CASP9,HSPA12A,CDYL,GALNT7,CCNF,LDB2,ANKRD10,BMP1,PRDM5,EIF4EBP2,NFKBIZ,TANC2,CCDC97,DDX58,KLF2,CDK17,FRMD4A,TBC1D1,C6orf106,NOTCH2,APBA1,TNFRSF19,PRRG4,CALR,DOPEY2,ITGA3,RALGPS2,LYPD3,PIK3AP1,BDH1,MSH2,RUNDC3B,PRKG1,SORL1,OSTF1,CD70,CACNA1D,PIKFYVE,KCTD3,GPR161,TRAK2,FAM69A,EPB41L5,GFPT1,GCC2,CEP89,LPGAT1,DCHS1,PTPRH,WHSC1,ANTXR1,NFIB,RASA1,STX3,PDE11A,FAS,DGKH,NT5C2,PLEKHH2,PRKAG2,TJP3,FAAH,ISM1,PELI2,C1orf21,APPL2,SFMBT1,PCDH19,PER3,MAP3K5,HOOK1,IFIH1,IRF1,EHD1,FRMPD3,PLA2G4A,SPRED1,SLC2A4,DLGAP5,S100A11,ST14,IQGAP1,RPS6KA1,CCDC110,ATP2C2,FLT3,NUDT12,MNS1,CYP39A1,ZFYVE9,EPM2A,NOV,IFIT1,EPHB4,PHKA2,NR2C1,MYO5B,SEC23A,CAPN6,PANK1,UTRN,TMEM144,PRKCQ,CBL,PRDM11,NIN,EPHA10,ZNF704,NRG1,NR3C2,COBL,MAMDC2,DENND5B,MRPS9,OTUD5,WASF3,ATP9A,CENPI,EPS8,PBX3,PNPLA5,LGALS3BP,WWP2,RNF128,OXCT1,PTEN,FUT8,ERBB3,MSH6,NCOA2,FARP2,PDGFC,RASGRF1,PCCB,ARAP2,CASK,ARHGEF28,ZC3H11A,DENND1B,DIAPH2,LRRC1,ARSK,GPLD1,RCBTB2,RIN3,TBX18,ABCB1,GRIN2D,ARSB,ESPL1,OCLN,USP16,JARID2,LTBP1,FAF2,DNER,TRIM68,TMC1,SH3KBP1,NKAIN3,SIPA1L2,HSF2,ARHGEF37,CDKL5,TSPAN6,IMPAD1,ANKFN1,DLG1,TRPC1,POF1B,SUN3,RAB20,ASH2L,NFU1,ARNT2,MYRIP,BTBD3,OLFML2A,ASXL1,ITCH,ACBD3,RNF165,ROR1,EDNRA,IARS2,RBM43,NR2C2,PPP1R12A,ABCG2,SAMD9,PHLPP1,QSOX2,FAM20C,FNIP1,LIMCH1,HLA-C,KNTC1,SLC12A2,GAD1,SNED1,ELK3,PDE5A,KIAA1109,HEATR5A,PDIK1L,NUBP1,EGFR,XKRX,ONECUT1,TMEM30A,NXPH4,ALPK3,JAK3,KLF7,LMO7,NCKAP5,ZSWIM5,PSME2,PDIA5,MRAS,MICALL2,MXD1,FRYL,SMO,RPN2,EPB41L4B,MAP3K3,SOAT1,ZNF525,TMTC2,DOCK5,STAT6,TLE1,VSIG10,SPTBN5,PLXND1,AKNA,LNP1,LIFR,SORT1,ARHGEF11,SH3D19,TRMT2B,FAM167A,XPR1,TMEM63A,KIF5B,IL17RB,SNX13,MLPH,BMP7,RRBP1,TOX2,KIAA0319,H2AFY,BRD7,MYO5A,PGM1,ADAM17,ASPM,MBNL3,OGDHL,TTC7A,MAP1B,KLHL2,SWAP70,RND3,FIBCD1,CSGALNACT1,UBE2D2,AHR,RAB3IL1,NGEF,ZNF596 |
| 1.480e-04 | -8.82 | transforming growth factor beta binding | molecular function | GO:0050431 | 16 | 9 | 16491 | 2452 |
CD109,LTBP1,ACVR1,TGFBR3,ACVRL1,VASN,TGFBR1,ITGAV,LTBP3 |
| 1.488e-04 | -8.81 | Metabolism of carbohydrates | REACTOME pathways | R-HSA-71387 | 274 | 64 | 8202 | 1235 |
GAA,SLC35D2,SLC2A4,PAPSS2,UGP2,AGRN,HSPG2,SLC25A13,HEXB,SDC1,PRKACA,EXT2,CHST2,EPM2A,CHPF,CALM2,NUP210,PAPSS1,AKR1B1,GYS1,GOT1,PHKA2,CHP1,PFKFB2,MGAM,HS6ST1,HPSE,HS3ST3B1,B4GALT3,ST3GAL1,NDST3,PPP2R5D,HS6ST3,GALK1,ENO2,SDC4,CALM3,B4GALT4,DSE,GNS,PFKL,GPC3,NUP85,PHKG2,B3GALT6,CHSY3,HMMR,B3GNT7,PGM1,B3GNT2,GUSB,CALM1,PYGL,PKM,GLCE,SLC35B3,PRPS2,CSGALNACT1,GLB1,MDH1,B4GAT1,NUP37,ARSB,NUP58 |
| 1.488e-04 | -8.81 | Tyr_kinase_AS | interpro domains | IPR008266 | 95 | 28 | 18293 | 2672 |
TNK1,LMTK3,TESK1,EPHA4,RET,ERBB2,TESK2,TEC,ROR1,YES1,EPHA1,FLT3,DDR1,MERTK,EGFR,TXK,INSR,FYN,JAK1,IGF1R,FGFR2,AXL,PTK7,RYK,PLK4,EPHB4,JAK3,SYK |
| 1.494e-04 | -8.81 | biliary_tract-gallbladder-other-dysplasia-carcinoma_in_situ | COSMIC cancer mutations | biliary_tract-gallbladder-other-dysplasia-carcinoma_in_situ | 23 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,GNA11,EGFR |
| 1.494e-04 | -8.81 | biliary_tract-gallbladder-other-adenoma | COSMIC cancer mutations | biliary_tract-gallbladder-other-adenoma | 23 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,GNA11,EGFR |
| 1.502e-04 | -8.80 | GSE12366_GC_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE12366_GC_BCELL_VS_PLASMA_CELL_UP | 180 | 45 | 17758 | 2588 |
CCDC109B,TUBB4B,INPP5D,XYLT1,TP53,LMCD1,FAM102B,CALM3,PBX3,ETS1,QSOX2,CALM2,ZYX,DAZAP1,VASP,PCNA,ADD3,PTEN,CD22,KIF22,OSTF1,RCAN3,CTDSP2,METAP2,FIGNL1,CALM1,KCTD20,BCL2L13,POLD3,RNF19B,DCP2,RASGRP2,DDX23,AP1AR,CDCA4,FNTA,CDCA5,TMOD2,KPNA2,CYP2U1,TMEM159,UBE2C,MYL12B,ESPL1,RAD21 |
| 1.502e-04 | -8.80 | GSE12366_NAIVE_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_NAIVE_VS_MEMORY_BCELL_DN | 180 | 45 | 17758 | 2588 |
SLC35D2,MPZL1,CD82,CORO1B,CAPN2,CDKN2C,WEE1,ENTPD4,KCNN4,SLC16A6,MGAT4A,LMO4,OSBPL3,BHLHE41,AIM1,PASK,PAPSS1,ZDHHC13,PRKCI,PDE4D,FAIM,CLIP2,CRTAP,POU6F1,GFPT1,PQLC3,BTNL9,GCLC,DENND1B,SYBU,PARP4,EMP3,WHSC1,RAD17,RNF19B,DGKE,FAS,NAAA,TWSG1,FGD6,CLIP4,GRAMD1C,CD81,SLC27A3,TMEM14A |
| 1.502e-04 | -8.80 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN | 180 | 45 | 17758 | 2588 |
DDX58,CCDC109B,IL15RA,ARHGEF11,PARP14,TRIM5,TAP1,UBE2Z,HERC5,PDGFRL,GPR180,SAMD9,CD274,HERC6,DUSP5,MXD1,TMCC3,DTX3L,OTUD1,FAM46A,IRF2,IFIT1,TINAGL1,OAS3,ETV7,APOBEC3G,DNAI1,PCGF5,ARAP2,RIPK2,PLSCR1,PAPD7,USP18,IFIT3,FAS,PI4K2B,PTGS2,C19orf66,SECTM1,NLRC5,CMPK2,SLC31A2,IFIH1,CSRP2,IRF1 |
| 1.506e-04 | -8.80 | JIANG_TIP30_TARGETS_UP | MSigDB lists | JIANG_TIP30_TARGETS_UP | 42 | 16 | 17758 | 2588 |
PPP1R2,ITGA6,PTTG1,NDC80,CALCRL,RAD17,CDK1,IER3,ENPP1,WEE1,FYN,CYR61,AXL,BCL6,NDE1,DUSP1 |
| 1.506e-04 | -8.80 | AMIT_EGF_RESPONSE_40_HELA | MSigDB lists | AMIT_EGF_RESPONSE_40_HELA | 42 | 16 | 17758 | 2588 |
SEC23A,CDKN2AIP,KCNJ12,HES1,KLF2,NR4A1,CCNL1,EGR3,NFIB,DUSP5,IER3,PTGS2,ZFP36,SGK1,CBX4,DUSP1 |
| 1.507e-04 | -8.80 | negative regulation of cell cycle process | biological process | GO:0010948 | 238 | 57 | 16441 | 2455 |
CAST,PSME2,CTDSPL,PTTG1,PSMD7,TP53,PSMD10,PSME1,FANCI,IER3,TP73,SUSD2,CCND1,TFAP4,E2F7,RB1,CCNA2,PSMD1,RPS6KA2,PTEN,DACT1,BMP7,PSMC2,FBXO7,MSH2,H2AFY,CDKN1B,BRD7,DAB2IP,BUB1,KANK2,CTDSP2,PSMA5,PLK1,PSMB4,HMGN5,CDC20,RGCC,AURKB,CCNF,NUBP1,PSMA4,CDK1,JADE1,FGFR2,PSMD3,OVOL1,PKD2,GPER1,FHL1,UBE2C,E2F8,ESPL1,PSMC1,MIIP,PRKAR1A,CTDSP1 |
| 1.507e-04 | -8.80 | SUSD4 (sushi domain containing 4) | protein interactions | 55061 | 39 | 16 | 16036 | 2547 |
ADAMTS2,DHPS,HAPLN3,CERCAM,FAM234B,PLXNA1,TXNDC11,ARSK,MAN2A2,FRAS1,ITGA7,IL17RA,ITGAV,MOXD1,ARSB,KDELC2 |
| 1.508e-04 | -8.80 | KINESINHEAVY | prints domains | PR00380 | 44 | 16 | 4759 | 661 |
KIF3C,KIF20A,KIFC2,KIF1C,KIF23,KIF20B,KIF13A,KIF2C,KIF11,KIF26A,KIF5B,KIF13B,KIF14,KIF22,CENPE,KIF12 |
| 1.521e-04 | -8.79 | organelle subcompartment | cellular component | GO:0031984 | 296 | 67 | 17570 | 2579 |
ARFGEF1,RGS20,TGOLN2,SNX9,BCAP31,CHST2,SLC9A7,NCS1,CHPF,INPP5E,AP1M2,CDH1,STIM1,ARL1,FUT1,DNM2,RAB27B,SULF2,CPD,ATL1,COG2,LAP3,KIF13A,SLC11A2,ARFRP1,RAB38,OPTN,STX10,WIPI1,ATP7B,CANT1,RAB29,B4GALT3,ST3GAL1,ARFGEF3,PIFO,GOLIM4,SORT1,SCOC,ATP9A,BACE1,RAB6A,B4GALT4,HLA-A,FUT2,NECAB3,OCRL,FUT8,SORL1,TMED2,GCNT1,NAGPA,B3GALT6,MOB4,CHSY3,GCC2,FURIN,FBXO8,FAM109A,GALNT3,GNAS,NUCB1,ARAP1,CSGALNACT1,RAB31,GPER1,GOLGB1 |
| 1.523e-04 | -8.79 | ACTIN_FILAMENT_ORGANIZATION | MSigDB lists | ACTIN_FILAMENT_ORGANIZATION | 23 | 11 | 17758 | 2588 |
ARHGEF10L,TSC1,SORBS1,NF2,DLG1,ARAP1,EZR,SORBS3,BCAR1,SHROOM2,RND1 |
| 1.523e-04 | -8.79 | EGUCHI_CELL_CYCLE_RB1_TARGETS | MSigDB lists | EGUCHI_CELL_CYCLE_RB1_TARGETS | 23 | 11 | 17758 | 2588 |
CCNE2,CCNA2,KIF20A,NDC80,NEK2,CDCA8,BUB1,CENPE,KIF11,CDC25C,SMC4 |
| 1.523e-04 | -8.79 | MODULE_196 | MSigDB lists | MODULE_196 | 23 | 11 | 17758 | 2588 |
MAP2,TUBB4B,SNTB2,KIF14,KIF23,KIF2C,CENPE,ARSB,KIF11,MAP1B,TUBA4A |
| 1.523e-04 | -8.79 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | MSigDB lists | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | 23 | 11 | 17758 | 2588 |
DGKH,DGKQ,DGKA,PRKCQ,ITPR2,ITPR3,TRPC3,DGKG,RASGRP1,DGKE,RASGRP2 |
| 1.529e-04 | -8.79 | positive regulation of cell adhesion | biological process | GO:0045785 | 362 | 80 | 16441 | 2455 |
IL15,RET,GATA3,ERBB2,IL18,EGR3,CD274,EMP2,TNFSF9,CD46,NPNT,IL6ST,PIK3CA,DNM2,TNFRSF18,EPB41L4B,FLOT2,RASGRP1,CD55,BAG4,RIPK2,AKT1,LGALS8,DMTN,UTRN,PRKCQ,PTPRJ,FYN,TRIOBP,NOD2,NRG1,PIEZO1,RAP1GAP,DHPS,ADGRG1,TRAF2,HLA-E,ARHGEF7,ITGA6,SDC4,FLOT1,FBLN1,EFNB1,HLA-A,CALR,SPP1,ITGA3,CYR61,BMP7,PAK2,IGFBP2,WNT3A,RAG1,MAP3K7,CITED2,SYK,SOCS5,EPB41L5,HES1,RHOA,FMN1,PIK3R1,YES1,EPHA1,ILK,STX3,CD83,BCL10,TSC1,PLPP3,CSF1,TBX18,NR4A3,ITGAV,ICOSLG,ARPC2,JAK3,L1CAM,COL16A1,FOXA1 |
| 1.531e-04 | -8.78 | glycosaminoglycan metabolic process | biological process | GO:0030203 | 166 | 43 | 16441 | 2455 |
SLC35D2,AGRN,PAPSS2,HSPG2,IL15,XYLT1,HEXB,SDC4,B4GALT4,DSE,SDC1,EXT2,CHST2,CHPF,GNS,GPC3,IMPAD1,XYLT2,PAPSS1,GALNS,PIM1,CHP1,HMMR,CHSY3,B3GALT6,B3GNT7,B3GNT2,AKT1,GUSB,PXYLP1,GLCE,FUCA1,HS6ST1,HPSE,SLC35B3,CSGALNACT1,GLB1,B4GAT1,HS3ST3B1,B4GALT3,ARSB,ST3GAL1,NDST3 |
| 1.539e-04 | -8.78 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | 175 | 44 | 17758 | 2588 |
BIN1,UBASH3B,ITGA6,TDRKH,FAM78A,SYTL4,SNN,TSPAN17,EPS8L2,H1FX,CORO1B,OTUD1,FAM111A,NUP210,ANKS6,GALNS,TAGLN2,PIM1,CITED2,DLG3,FLOT2,SLC16A5,DUSP1,FBXL16,MMD,KIFC2,BLVRA,LDB2,FOS,TYSND1,SOCS3,ANKRD10,IRS2,AREG,WDR19,ARRB1,NFKBIZ,KLF11,PIEZO1,ZMIZ1,NRGN,TOB1,MAFF,IRF1 |
| 1.539e-04 | -8.78 | MODULE_126 | MSigDB lists | MODULE_126 | 175 | 44 | 17758 | 2588 |
CCNE2,DYRK3,FOXM1,DAP,ETV5,BIK,MGST2,CCNB1,SLC20A1,MECOM,PCNA,CCNA2,ITGA3,IRAK1,UBE2T,GTF2F2,CKS1B,BUB1,PANX2,GFI1,ETV4,ULBP2,MSH6,ABCC1,SEMA3B,CKS2,PPIF,GCC2,PCDH1,MFI2,MAPKAPK3,ASPM,SLC25A5,CDK1,ANKRD6,IARS2,E2F1,AURKA,CENPE,GLA,ARPC2,NCAPG2,MELK,MAPK12 |
| 1.539e-04 | -8.78 | GSE2706_UNSTIM_VS_2H_LPS_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_DC_DN | 175 | 44 | 17758 | 2588 |
PARP14,TAP1,SOD2,UBE2Z,P2RX7,CD274,BCL2L1,HERC6,DUSP5,ICAM1,ZNF385B,OTUD1,BTG3,ITGB8,SELK,IFIT1,RASGRP1,LAMP3,RIPK2,TNIP1,PAPD7,PLAUR,RAPGEF2,PTGER4,PIM3,IFIT3,TP53INP2,SPAG1,SOCS3,GALNT3,BTG1,MFSD2A,NFKBIA,SLC2A6,SIPA1L1,NR4A3,NFKBIZ,IRF7,HS3ST3B1,EFNA1,GEM,IFIH1,IRF1,EHD1 |
| 1.553e-04 | -8.77 | antigen processing and presentation of endogenous antigen | biological process | GO:0019883 | 13 | 8 | 16441 | 2455 |
HLA-B,TAPBP,HLA-E,TAP1,ERAP1,HLA-C,HLA-A,ERAP2 |
| 1.563e-04 | -8.76 | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | MSigDB lists | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | 105 | 30 | 17758 | 2588 |
CPD,LMO7,TGIF1,SLC35D2,TBC1D1,IQGAP1,LPGAT1,ITGA6,SOX9,TGFBR1,DUSP4,SLC20A1,DDR1,NCS1,HMGXB4,DHX32,IER3,PDGFA,BTG1,PDCD10,RBM47,CTGF,FGD6,SGK1,CLDN4,MAL2,LGMN,UNC5B,C9orf72,KCTD3 |
| 1.569e-04 | -8.76 | ROME_INSULIN_TARGETS_IN_MUSCLE_UP | MSigDB lists | ROME_INSULIN_TARGETS_IN_MUSCLE_UP | 416 | 88 | 17758 | 2588 |
LAMP1,SORBS1,ST13,UGP2,GNPDA1,SLC2A8,ATP8A1,TMEM41B,LMCD1,GMPR,C1orf198,TGOLN2,MORF4L2,SH3KBP1,EPM2A,ATP6V0B,HSF2,PSMC2,TAX1BP3,APIP,IFIT1,PDE4D,TECR,CLCN3,TIMP2,NFE2L1,MTRF1L,KIF1C,PPP1R14C,GTF2A2,H2AFV,DAG1,VCP,RHEB,ARF4,DPYSL3,MSL1,POPDC3,PEX2,MYL12B,TC2N,RRAGD,CMAS,LGALS3,SCOC,PPP1R12A,PPP1R2,BVES,NCKAP1,TSPAN7,KIAA1161,PPP2R3A,COX7A2,KIF5B,CAPN2,ADD3,OXCT1,PTEN,MTMR10,SLAIN2,SELK,HLA-C,SGCB,TMED2,DCAF6,MRPS33,PSMB4,MPP1,AMFR,PIK3R1,PPARA,STRADB,KIAA1109,NUBP1,NFIB,PSMA4,PLIN5,ENDOD1,SCARB2,TIMP3,TRIM69,C1orf21,DCUN1D1,UACA,NDFIP1,PKIA,USP16,RGMA |
| 1.573e-04 | -8.76 | HALLMARK_HYPOXIA | MSigDB lists | HALLMARK_HYPOXIA | 196 | 48 | 17758 | 2588 |
GAA,GALK1,ENO2,UGP2,CDKN1C,NDRG1,SDC4,PDGFB,ETS1,CHST2,IER3,SRPX,CTGF,CYR61,PFKL,ZFP36,GPC3,CDKN1B,GYS1,PIM1,CITED2,TIPARP,SULT2B1,DUSP1,B3GALT6,PGM1,NR3C1,S100A4,PLAUR,BNIP3L,KDELR3,AK4,PDK3,FOS,DPYSL4,KDM3A,EGFR,IRS2,PGF,BTG1,SLC6A6,P4HA2,PRKCDBP,EFNA1,MAFF,CSRP2,KLF7,RRAGD |
| 1.573e-04 | -8.76 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN | 196 | 48 | 17758 | 2588 |
PNISR,PINK1,ADD1,HLA-E,ZCCHC24,ETV5,BTN3A1,KCTD12,MGST2,ITPR2,PKN1,VASH1,ERP29,KTN1,SNX13,FRY,METTL7A,IQCE,ATP5H,PLCG2,RUNDC3B,SORL1,H2AFY,AHCY,NPTN,CLIP2,ALDH3A2,CTNNAL1,S100A4,CORO2A,ESYT1,FOS,IDH1,POR,USP6,FUCA1,STX10,RCBTB2,HTT,PRCP,STK38,PLA2G15,PNPLA6,NRG1,HOXB13,LTA4H,NRGN,ABCG1 |
| 1.573e-04 | -8.76 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP | 196 | 48 | 17758 | 2588 |
KIF3C,RECQL,PAPSS2,NQO1,ATP9A,TRAF2,FAM134A,PPFIBP2,FBXO6,HES2,SPSB1,PHF1,AKIRIN1,SNX13,ST5,RPS6KA2,CA2,RALGPS2,CNTRL,SH3BP1,RGS3,BCL6,ABCD1,CLIP2,NAGA,MX1,QSOX1,TIMP2,COL6A2,CTNNAL1,SPA17,TCN2,ULK2,BSDC1,NCOA3,RPL12,COQ10A,ACVRL1,PRDM5,NR4A3,CANT1,ARFGAP3,RPL22,F2RL1,ST3GAL1,USF2,JARID2,ABCG1 |
| 1.575e-04 | -8.76 | GNF2_CD53 | MSigDB lists | GNF2_CD53 | 59 | 20 | 17758 | 2588 |
HLA-E,INPP5D,RPS6KA1,HLA-F,TAP1,SELL,ARHGDIB,PSME1,GRK6,HLA-A,LCP1,HLA-B,RAC2,TAPBP,STAT6,PAK2,FXYD5,OSTF1,HLA-C,PIK3CD |
| 1.575e-04 | -8.76 | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | 170 | 43 | 17758 | 2588 |
BIN1,MAN2B2,CCDC109B,ARHGEF11,NDRG1,TSC22D3,UBASH3B,EPHA4,SNN,MXD1,H1FX,CORO1B,IRF2BPL,FAM111A,FNIP1,PDE4D,CITED2,MYLIP,KCTD3,C9orf72,DUSP1,KIFC2,ITCH,RAPGEF2,UTRN,DIAPH2,TP53INP2,NMT2,SOCS3,IRS2,TRAM2,PTGS2,AREG,PELI2,PRDM5,CCDC69,KLF11,TOB1,MAFF,CPEB2,KLF7,PCSK5,FAM134B |
| 1.580e-04 | -8.75 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | 537 | 109 | 17758 | 2588 |
CCNI,GPR107,NQO1,GALNT12,NDRG1,MCOLN3,FAM102B,IL27RA,NENF,FAM101B,SLC20A1,PHLDA1,TNFSF9,CHST2,NCS1,SH3KBP1,ZYX,ENTPD4,ZDHHC12,SLC44A1,SERINC2,STEAP3,MINPP1,ETHE1,LMAN1,TIAM1,IL1RAP,RASGRP1,LAMP3,SULF2,SNX8,SOAT1,CD55,FOPNL,LYRM1,CDYL,CBX6,ACO1,ATP1B1,DUSP4,CD40,DOCK5,ALCAM,BOLA3,FASTKD1,LIMK1,P4HA2,PNPLA6,RAB11FIP1,MAPK13,SLC27A3,ISOC1,MAFF,NFKBIE,MPZL1,GTF3A,TGFBR1,NFAT5,CD109,KIF5B,AKIRIN1,MARCH8,B3GALNT1,SPP1,RAC2,VASP,LYPD3,SPIN4,CALD1,BHLHE41,KCNN4,COL6A1,RANBP1,TAGLN2,FAR2,MCCC2,MYO5A,ABCC1,FAM69A,P2RX4,SUN2,PDGFC,HPS3,CTNNAL1,MAPKAPK3,PLAUR,DENND1B,AK4,HMG20B,GGH,FNDC3A,BCAR3,NAAA,SLC6A6,ETS2,MFSD2A,CSF1,PAPD5,ITPR1,SLC25A40,NR4A3,DTX4,RAB31,DCUN1D1,NETO2,ALG2,MAP3K5,TBC1D4,ACOT7 |
| 1.593e-04 | -8.75 | Kinesins | REACTOME pathways | R-HSA-983189 | 26 | 12 | 8202 | 1235 |
KIF5B,KIF3C,KIF20A,KLC2,KLC3,KIF23,KIF22,RACGAP1,KIF2C,CENPE,KIF11,KIF26A |
| 1.598e-04 | -8.74 | TACTTGA,MIR-26A,MIR-26B | MSigDB lists | TACTTGA,MIR-26A,MIR-26B | 293 | 66 | 17758 | 2588 |
LTBP1,TMEM184B,LGR4,MRAS,SNN,SH3KBP1,RCN1,RPS6KA2,MITF,POF1B,NTN4,ZNF462,TMEM200B,MARK1,ACVR1C,PDHX,ULK2,OSBPL2,PTGS2,ALDH5A1,MAP2,KCNK1,PTER,KPNA2,REEP4,CMTM4,FGD1,RBM24,TAB3,SH3D19,ZCCHC24,ARL4C,TRIB2,DUSP5,SSX2IP,ZFX,E2F7,ANKS1B,PAK2,DAPK1,FNIP1,PIM1,NCEH1,SLC12A2,RPGR,NFE2L3,ACBD5,STRADB,KBTBD8,XKRX,ACADSB,SLC4A4,FA2H,PLOD2,CCDC6,PELI2,CSNK1G1,RAP2C,AMMECR1,STK39,HMGA1,TRPC3,TBC1D4,TOB1,EHD1,FAM45A |
| 1.598e-04 | -8.74 | positive regulation of cell motility | biological process | GO:2000147 | 379 | 83 | 16441 | 2455 |
ACVR1,ATP8A1,RET,COL18A1,GATA3,CD274,CAMK1D,HDAC6,PDGFB,PDGFA,EPCAM,DAPK2,TNFRSF18,DAB2IP,TWIST1,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,SEMA3B,DOCK4,BAG4,AKT1,DMTN,SYNE2,DOCK5,IRS2,PTGS2,PLCG1,MYLK,FAM110C,F2RL1,HSPB1,SEMA6B,ANXA3,LGALS3,ARHGEF7,SOX9,SELL,CBLL1,ETS1,FBLN1,SRPX2,ICAM1,NRP2,ITGA2B,HDAC9,CALR,BMP2,RAC2,CXCL16,PDCD10,ITGA3,IGF1R,CYR61,NTN1,EPB41L5,SUN2,RHOA,ADAM17,RAPGEF2,ANO6,PIK3R1,FURIN,KIF20B,EPHA1,ILK,BCAR1,EGFR,GPLD1,ONECUT1,SWAP70,INSR,SEMA4D,PLPP3,CSF1,FGF18,ITGAV,GPER1,CFAP20,SEMA3A,DRD1 |
| 1.608e-04 | -8.74 | KATSANOU_ELAVL1_TARGETS_UP | MSigDB lists | KATSANOU_ELAVL1_TARGETS_UP | 165 | 42 | 17758 | 2588 |
SORT1,NFKBIE,PSME2,EPHA4,NES,CCDC68,GDF15,DNER,FAM101B,DHRS3,PDGFB,SPSB1,FZD6,SYTL2,SUSD2,ITGA3,CTSC,ALDH1A3,FJX1,DAPK1,NTN4,IGFBP2,RGS5,NOTCH3,PCGF5,TMTC1,HN1L,SAT1,PDE5A,MEST,LDB2,AIF1L,MYOM1,ATP10D,TCN2,FAS,PITX2,FAM177A1,PLEKHH2,PLOD2,MYL12B,DMPK |
| 1.611e-04 | -8.73 | MARTENS_BOUND_BY_PML_RARA_FUSION | MSigDB lists | MARTENS_BOUND_BY_PML_RARA_FUSION | 422 | 89 | 17758 | 2588 |
LFNG,RPS6KA1,TMEM41B,NDRG1,CD82,FAM78A,F11R,ITPR2,GRK6,PIGL,FLT3,KREMEN1,GNB2,LTBP3,DAPK2,APLP2,NUP210,RPS6KA2,PLCG2,FOSB,CAPG,TMEM143,DNM2,RAB20,IQCD,ECE1,FGFR1OP2,SULF2,SUSD3,TMCC2,TIMP2,MBP,CXXC5,PLEKHO1,MTRF1L,C15orf39,IDH1,PTPRJ,PSMD3,RAB11FIP1,PLXND1,AKNA,ANXA11,KLF2,LASP1,CDS2,GGA1,UBASH3B,EFHD2,NDUFA4,GTF3A,LBR,DUSP5,ICAM1,SIRPA,RAC2,MDM1,VASP,GNB5,ADRBK1,PTEN,PIK3AP1,TOX2,TAGLN2,CTSD,PLCB2,NUP85,CAMK2G,PVRL4,B3GNT7,ALDH2,IFITM3,GUSB,CORO2A,RUNX3,RASGRP2,SLC6A6,ITPR1,ARAP1,RAB31,ARRB1,UACA,HMGA1,ZMIZ1,SERPINB1,PTGES,TMEM173,DEF6,IRF1 |
| 1.613e-04 | -8.73 | protein tyrosine kinase activity | molecular function | GO:0004713 | 142 | 38 | 16491 | 2452 |
TNK1,DYRK3,RET,EPHA4,TESK2,ERBB2,PDGFRL,TEC,MERTK,DDR1,FLT3,NRP2,WEE1,IGF1R,MAP3K9,NPTN,ERBB3,EPHB4,SYK,RIPK2,TESK1,EPHA1,ROR1,YES1,EGFR,TXK,EPHA10,FYN,INSR,JAK1,FGFR2,PTK7,AXL,KIAA1804,RYK,MAP3K11,JAK3,MELK |
| 1.613e-04 | -8.73 | JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP | MSigDB lists | JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP | 110 | 31 | 17758 | 2588 |
MAP3K3,GRN,LAMP2,TMCC2,SLC2A4,GOLIM4,ADD1,FIGNL1,SH3D19,FOXJ2,AES,GMCL1,COL7A1,RNF113A,DENND2D,NRP2,LYSMD4,FECH,PTPRF,CYHR1,ADD3,NR1D2,ARL1,PHTF1,FUT8,ANKRD12,ADAM15,WWP1,DGKG,NRBP1,SMAGP |
| 1.621e-04 | -8.73 | RHO GTPases activate CIT | REACTOME pathways | R-HSA-5625900 | 16 | 9 | 8202 | 1235 |
MYL9,RHOA,CIT,KIF14,PRC1,CDKN1B,MYH14,MYL12B,RHOB |
| 1.623e-04 | -8.73 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP | 191 | 47 | 17758 | 2588 |
FARP1,NFKBIE,BLVRB,PPFIBP2,MCCC1,TDRKH,C3orf18,FLT3,BCAP31,SDF4,LMNA,GNS,APLP2,PHYHIP,C7orf49,METTL7A,DACT1,AHCY,TINAGL1,NAGA,FAM69A,LAMP2,QSOX1,MLEC,MMD,GUSB,PYGL,NUSAP1,RAB38,BLVRA,NPC2,DAG1,CD83,IL1R1,TRAM2,HTT,SPINT2,PLA2G15,NR4A3,ARRB1,MAOA,ADIPOR1,KLF11,GLA,SPRY4,PDXK,ZMIZ1 |
| 1.623e-04 | -8.73 | GSE20715_0H_VS_24H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_LUNG_UP | 191 | 47 | 17758 | 2588 |
DYNLRB1,PARP12,PPFIBP2,FHDC1,SELL,PKP2,RHPN2,FAM198B,EMP2,ETS1,BEX2,NRP2,PPP2R3A,PDGFA,CDKN2C,RAC2,MDM1,NUP210,CA2,RALB,PLCG2,TRIM21,TSPAN13,ALDH7A1,RFX5,MYLIP,CAMK2G,EPB41L5,PRODH,PMPCB,ARAP2,HPS3,PLEKHA6,ELK3,MPP1,TCF7,MRPS35,ARHGDIB,EPHA1,TANC1,DCTN6,HLA-B,SLC6A6,SERTAD2,SEMA4D,SERPINB1,GAB1 |
| 1.623e-04 | -8.73 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP | 191 | 47 | 17758 | 2588 |
TXN,UGP2,NFKBIE,ENO2,TRIP10,NDRG1,ARL4C,SOD2,SELL,DUSP5,IER3,TYMP,SRPX,RALB,LYPD3,AKR1B1,DOCK4,PGM1,WNT10B,TNIP1,SLC39A8,CRIP2,CDYL,LITAF,ACO1,AK4,EMP3,ELK1,RNF19B,CYB5A,PLEKHB1,CD83,OPTN,BTG1,ETS2,PVRL2,H1F0,FGFR2,RND3,SPINT2,IRF7,GEM,UNC5B,TBC1D4,SLC31A2,EHD1,ARHGEF4 |
| 1.623e-04 | -8.73 | GSE17721_12H_VS_24H_CPG_BMDM_UP | MSigDB lists | GSE17721_12H_VS_24H_CPG_BMDM_UP | 191 | 47 | 17758 | 2588 |
CASP3,TTC39B,SERPINE2,IL15,HEBP1,CCNL1,INTS8,SLC1A3,FBXO6,PLA2G16,FAM46C,PARM1,CDKN2C,FAM20C,BHLHE41,ZFP36,MITF,KANK2,HMGCL,ECE1,TFG,ETV4,SUN2,LGALS8,UXT,PIK3R1,SHARPIN,PTGER4,EZR,TNFAIP8L1,PKMYT1,CD40,ASB13,FAS,ENDOD1,CARHSP1,AP1AR,PPP2R5A,PVRL2,ZDHHC20,CHMP4B,AKNA,SLC31A2,SEMA3A,IFIH1,PTGES,ANXA11 |
| 1.630e-04 | -8.72 | PPP1CC (protein phosphatase 1, catalytic subunit, gamma isozyme) | protein interactions | 5501 | 240 | 60 | 16036 | 2547 |
TPRN,ENO2,PPP1R2,NUAK1,RASSF7,NDC80,TP53,CUL1,NUF2,BCL2L1,FBXO6,CCNB1,HDAC6,LBR,ZFYVE9,LMNA,SH3RF2,CCND1,RASSF8,ZFYVE16,RB1,PCNA,PPP1R10,TACC2,DPYSL2,DACT1,PPP1R16A,NEK2,GYS1,ASH2L,APIP,PPP1CA,ACAD8,HSPA2,SGCE,AKT1,UXT,KCTD20,SCRIB,CDCA2,TNS1,LRRC1,ERBB2IP,RNF19B,CDK1,RANBP9,NMT2,VCP,KDM4D,CTSL,PPP1CB,CLMN,HDAC1,AURKA,ZDBF2,B4GAT1,TMEM120A,TANC2,NRBP1,PHC1 |
| 1.660e-04 | -8.70 | regulation of neuron apoptotic process | biological process | GO:0043523 | 192 | 48 | 16441 | 2455 |
CASP3,GCLM,PINK1,TRIM2,CPEB4,NQO1,AGRN,GRIK2,SOD2,TP53,NES,GATA3,BCL2L1,SIX4,TP73,CTNNB1,KIF14,MSH2,PIK3CA,BAX,TFAP2A,PRKCI,ERBB3,EGLN3,LGMN,F2R,SOD1,KCNIP3,RHOA,GCLC,OXR1,CASP9,GRIN1,ILK,CDK5R1,RASA1,OPTN,MDK,FYN,HTT,BHLHB9,AXL,WFS1,MAP3K11,NR4A3,NR4A2,UNC5B,FAM134B |
| 1.664e-04 | -8.70 | Ras GTPase binding | molecular function | GO:0017016 | 224 | 54 | 16491 | 2452 |
EXPH5,PIFO,RALBP1,RUSC2,NDRG1,IQGAP1,EPS8,RASGRP3,SYTL4,NCKAP1,PKN1,MICALL2,DOCK11,CCDC64B,RIC1,ARHGEF16,SYTL2,RABGGTA,PAK6,ACAP2,NOXA1,MLPH,LLGL2,CDKL5,OCRL,PAK2,RANBP1,EXOC8,TNPO2,IQGAP3,MYRIP,C9orf72,SYTL3,MYO5A,RIMS2,MYO5B,DOCK4,SOD1,STRADB,DIAPH2,RANBP9,OPTN,RAB11FIP2,CORO1C,RIN3,SH3BP4,RAB11FIP1,TRIOBP,MAP3K11,ARHGAP4,ITPKA,RAP1GAP,DOCK9,EHD1 |
| 1.669e-04 | -8.70 | phosphatidylinositol 3-kinase binding | molecular function | GO:0043548 | 30 | 13 | 16491 | 2452 |
IRS2,CALM2,ATP1A1,FYN,INSR,IGF1R,PIK3AP1,CALM1,PIK3R1,DNM2,CALM3,DAB2IP,FLT3 |
| 1.669e-04 | -8.70 | fatty-acyl-CoA binding | molecular function | GO:0000062 | 30 | 13 | 16491 | 2452 |
ACBD5,SOAT1,ACADSB,ALDH6A1,ACAD10,ACBD3,DBI,ECI2,HMGCL,ACOX2,ACADM,ACAD8,ACOT7 |
| 1.673e-04 | -8.70 | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | 186 | 46 | 17758 | 2588 |
ELK4,CASP3,PLSCR4,NFKBIE,TRIM5,MMADHC,MICALL2,DSE,OAT,MXD1,EPS8L2,DNAJB9,SGPL1,ZFYVE16,NAPG,FICD,MITF,PRC1,TPST1,TNFRSF12A,SOCS5,LAMP2,DOCK4,RAPGEF2,CORO2A,COQ10B,AK4,FNDC3A,RHEB,FAS,SFXN1,DUOX1,FYN,PRKAG2,CASP7,C19orf66,ZFP30,S100A5,PPP1CB,ZNF165,MYL12B,ESPL1,JARID2,EHD1,NXT2,RAD21 |
| 1.682e-04 | -8.69 | ZHU_CMV_ALL_UP | MSigDB lists | ZHU_CMV_ALL_UP | 120 | 33 | 17758 | 2588 |
PLA2G4A,ENO2,TRIM5,HLA-E,TAP1,GMPR,EMP2,RB1,SP100,RANBP1,TRIM21,IRF2,IFIT1,PIM1,MANF,LGMN,TUBA4A,REC8,MX1,B3GNT2,CD55,NR4A1,BCL7B,NUBP1,RAB2B,PTGS2,SCARB2,NFKBIA,NR4A3,ATP6V1C1,IFI6,PSMC1,IRF1 |
| 1.696e-04 | -8.68 | regulation of neuron death | biological process | GO:1901214 | 239 | 57 | 16441 | 2455 |
CASP3,GCLM,PINK1,TRIM2,CPEB4,NQO1,AGRN,GRIK2,TRAF2,SOD2,TP53,NES,GATA3,BCL2L1,SIX4,TP73,CTNNB1,KIF14,MSH2,PIK3CA,PRKCI,BAX,TFAP2A,SORL1,ERBB3,EGLN3,LGMN,F2R,CHP1,SIRT1,SOD1,KCNIP3,RHOA,AKT1,GCLC,OXR1,CASP9,GRIN1,PPARA,ILK,ELK1,CDK5R1,RASA1,OPTN,MDK,FYN,HTT,BHLHB9,WFS1,AXL,MAP3K11,NR4A3,CHMP4B,NR4A2,UNC5B,MAP3K5,FAM134B |
| 1.719e-04 | -8.67 | MULLIGHAN_MLL_SIGNATURE_2_UP | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_UP | 400 | 85 | 17758 | 2588 |
ARHGAP11A,LAMP1,PLA2G4A,GAA,IQGAP1,RPS6KA1,HEXB,TGOLN2,GRK6,ISOC2,MGST2,HDAC6,ECI1,REPS1,DENND2D,SDF4,NUP210,KHNYN,P4HB,IQCE,CAPG,SNX10,IL10RB,NAGA,LAMP2,PPIF,PTPN9,S100A4,HTATIP2,EAF2,SLC17A5,C15orf39,RNF19B,ABR,LCP1,ALDH3B1,RBM47,HOXA9,SLC9A6,TDRD7,SH3GLB2,MAPK13,EIF4EBP2,RGS14,SLC27A3,NRGN,GRN,ARHGEF3,PPP1R2,TRAPPC10,RASSF7,EFHD2,PBX3,RAB6A,ARHGEF40,PRRG4,SIRPA,SAC3D1,M6PR,GNS,TNS3,RAC2,IRAK1,TAF1B,TBCD,RRBP1,ZDHHC13,IL17RA,CNPY3,ALDH3A2,SYK,S100A6,NAGPA,PLAUR,PIP4K2C,RNPEP,DDX23,MAPKAPK2,ITGA7,SFMBT1,PITPNA,CTSA,ARPC2,PLIN3,ESPL1 |
| 1.721e-04 | -8.67 | PRC2_EZH2_UP.V1_DN | MSigDB lists | PRC2_EZH2_UP.V1_DN | 181 | 45 | 17758 | 2588 |
SLC35D2,IL15RA,ARL4C,CCDC68,NES,KCTD12,COL4A5,SRPX2,TSPAN7,SCML1,B4GALNT1,BMP2,PDGFA,KIAA0895,PAQR5,ALDH1A3,OPN3,MTMR10,CD70,TSPAN13,ETV4,OSGIN1,ERAP2,FAM69A,TUBA4A,ORAI2,MCTP1,OSTM1,PCBP3,C3orf52,PCTP,POPDC3,COL13A1,AMMECR1,TRAF3IP1,OTUB2,YOD1,NR4A2,KLK7,KLF11,F2RL1,SEMA3A,L1CAM,NR3C2,PKIA |
| 1.730e-04 | -8.66 | WANG_TUMOR_INVASIVENESS_DN | MSigDB lists | WANG_TUMOR_INVASIVENESS_DN | 202 | 49 | 17758 | 2588 |
CCNI,TCF25,PPP1R12A,DLGAP5,IQGAP1,HABP4,RACGAP1,DHRS3,ECI1,ABCD4,C11orf84,APLP2,SPP1,WDFY1,TGFBR3,IRAK1,CDH1,COL6A1,DLG1,CD9,ARVCF,MDFIC,ERBB3,GM2A,RNF11,FURIN,VAMP3,LITAF,BNIP3L,ATP1B1,ESYT1,NFIB,LCP1,BTG1,H1F0,HNRNPH2,KBTBD2,CORO1C,RYK,PPP1CB,SLC27A1,EFNA5,STK39,CTNND1,UBE2C,PPP2R2D,RAD21,ABCG1,XDH |
| 1.734e-04 | -8.66 | Frs2-mediated activation | REACTOME pathways | R-HSA-170968 | 233 | 56 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,PLCG1,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.736e-04 | -8.66 | Adherens junction | KEGG pathways | ko04520 | 73 | 24 | 6908 | 1076 |
LMO7,PVRL4,WASF3,RHOA,SORBS1,IQGAP1,ERBB2,TGFBR1,TCF7,YES1,EGFR,SSX2IP,PTPRF,RAC2,PTPRJ,INSR,FYN,CDH1,CTNNB1,IGF1R,PVRL2,CTNND1,MAP3K7,FARP2 |
| 1.736e-04 | -8.66 | Adherens junction | KEGG pathways | hsa04520 | 73 | 24 | 6908 | 1076 |
LMO7,PVRL4,WASF3,RHOA,SORBS1,IQGAP1,ERBB2,TGFBR1,TCF7,YES1,EGFR,SSX2IP,PTPRF,RAC2,PTPRJ,INSR,FYN,CDH1,CTNNB1,IGF1R,PVRL2,CTNND1,MAP3K7,FARP2 |
| 1.743e-04 | -8.65 | V$SP1_Q4_01 | MSigDB lists | V$SP1_Q4_01 | 234 | 55 | 17758 | 2588 |
KLF2,LASP1,UGP2,HOXB7,IQGAP1,NDRG1,NRG2,HDAC6,TIPRL,NFAT5,SH3KBP1,APLP2,FLII,RABEP2,SNX18,CDKL5,PRICKLE3,BHLHE41,SLC46A1,WWP1,KANK2,CACNA1D,MAP3K7,MYLIP,CAMK2G,CPD,CYP26B1,TEF,DRAP1,LYRM1,NUB1,EPHA1,PRKRA,ELK1,PDIK1L,GNA11,PLEKHB1,CDK5R1,RAB2B,PIAS3,ONECUT1,FNTA,TIMP3,SWAP70,CAMK2N2,PTK7,SLC9A6,SH2D3C,CORO1C,MAP3K11,AGBL5,NXPH4,PITPNA,KLF11,STARD13 |
| 1.743e-04 | -8.65 | LU_EZH2_TARGETS_DN | MSigDB lists | LU_EZH2_TARGETS_DN | 355 | 77 | 17758 | 2588 |
PAPSS2,FAM160B1,STIL,EXT2,ENTPD4,RPS6KA2,CTGF,SRPX,TACC2,HYLS1,PTPRE,NR2C1,TAF5,NRBF2,PBK,NBPF3,ACO1,ANLN,ASB13,IRS2,PI4K2B,AXL,MYLK,LRIG1,RAB11FIP1,ADIPOR1,KPNA2,NFKBIZ,RNASEL,RTN3,CMTM4,DLAT,FAM134B,ANKRD13D,PLSCR4,ALDH6A1,FAM169A,TAB3,POC1B,SH3D19,PM20D2,ETS1,SCML1,ALPP,CALD1,EXOC8,LIMCH1,FAM84B,FAR2,GAD1,SGCB,MCCC2,ATP2B1,IGSF3,GFPT1,NFE2L3,TBC1D8B,TACC1,BCL9,LITAF,CYFIP2,ANTXR1,C3orf58,EGFR,CDK5R1,DCP2,GLCE,MAGED2,CNTNAP1,DDAH1,CACHD1,CDKN2AIPNL,RAB11FIP2,PHLPP2,FAM83D,ZBTB34,LRRC57 |
| 1.743e-04 | -8.65 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | 644 | 127 | 17758 | 2588 |
LAMP1,PLA2G4A,DLGAP5,FOXM1,AASS,GALNT12,CTDSPL,NDC80,KIF2C,NANS,CCNB1,STIL,ECI1,BCAP31,FANCI,CCNA2,LMO4,AKR1B1,GOT1,KIF22,ASH2L,APIP,TECR,PDIA6,TMBIM1,DVL2,UPF3A,CYP1B1,PLK1,ENPP4,CENPA,HN1L,LGALS8,C3orf52,CDC20,HTATIP2,NUSAP1,PRKAR2B,GLO1,AURKB,CD40,CDC25C,CDK1,DAG1,GINS4,VCP,OPTN,SFXN1,SLC25A4,PAFAH1B3,RBL1,DNM1L,NGFRAP1,HOXA9,PEX2,INPP4B,DHTKD1,MAOA,SERPINB6,KPNA2,RTN3,DLAT,CMAS,ENO2,SERPINE2,LRRFIP2,FLOT1,ASL,PDIA3,C6orf106,CTSZ,GPSM2,ITGA2B,FZD6,LMNA,M6PR,MECOM,TOP2A,FAM111A,C16orf59,PPP1R10,PFKL,GATA2,BAX,NEK2,PRC1,ECI2,SRP54,CKS1B,PIM1,CKAP4,SMC4,HMMR,FADS2,ZWINT,PRSS23,KIF20A,ASPM,FHL2,CXorf57,PLS1,PDK3,BLVRA,POLD3,KIF11,NFIB,PRDX4,DDAH1,SWAP70,TIMP3,ETS2,PLOD2,HNRNPH2,KBTBD2,SLC2A6,SPINT2,RYK,AURKA,CENPE,FZD5,TMEM14A,CCNB2,TBC1D4,ESPL1,MELK,PKIA,SRSF9 |
| 1.744e-04 | -8.65 | regulation of growth | biological process | GO:0040008 | 635 | 128 | 16441 | 2455 |
ACACB,TNK1,AGRN,CACNA2D2,MORF4L2,PLXNA1,CCNB1,KIF26A,TP73,CDKN2C,CTGF,CDKL5,DPYSL2,PIK3CA,DNM2,SEMA3G,CTTN,SMARCA2,SOD1,ING1,ITCH,CDA,EZR,EAF2,SAV1,POR,ULK2,ENPP1,LIMK1,NKD1,NOD2,ADIPOR1,TMEM8B,CHPT1,SEMA6B,SERPINE2,SPP1,CYR61,MEGF8,PAK2,TNFRSF12A,NTN1,WNT3A,RIMS2,SOCS5,MFI2,PLS1,KIAA1109,ILK,CDK5R1,RASGRP2,GNAS,SERTAD2,INSR,SEMA4D,CSF1,CGREF1,SH3BP4,SEMA3A,RPS6KA3,DMPK,GAS2L1,NF2,FOXM1,RPS6KA1,TP53,ERBB2,NOV,KIF14,SMO,BCL6,CDKN1B,DAB2IP,ACSL4,LGMN,CDKN2D,SEMA3B,EBAG9,SIRT1,CDKN2AIP,PSRC1,AKT1,CLSTN1,SERTAD3,PRKCQ,SOCS3,JADE1,PTPRJ,WFS1,NRG1,EFNA5,PLXND1,TAOK2,IGFBP6,ARHGEF11,PSMD10,TGFBR1,HDGFRP2,CRABP2,SPR,PPP2R3A,SIX4,SGPL1,IL17RB,CXCL16,PTEN,GPC3,SGK3,H2AFY,ADAM15,SGK1,MAPK11,IGFBP2,OSGIN1,RHOA,FBLN5,ADAM17,WNT10B,BBS2,BCAR1,NDRG3,MAP1B,BTG1,ACVRL1,FGFR2,HOXB13,FHL1,L1CAM |
| 1.753e-04 | -8.65 | Mitotic G2-G2/M phases | REACTOME pathways | R-HSA-453274 | 117 | 33 | 8202 | 1235 |
CEP70,PPP1R12A,FOXM1,TUBB4B,CUL1,CCNB1,PRKACA,CKAP5,WEE1,CCNA2,CNTRL,CENPJ,CEP78,TUBGCP6,PLK4,NEK2,TUBG1,TUBA4A,PLK1,MYBL2,PRKAR2B,PKMYT1,CDC25C,BORA,CDK1,OPTN,E2F1,AURKA,PPP1CB,SSNA1,NDE1,CEP41,CCNB2 |
| 1.763e-04 | -8.64 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | 597 | 119 | 17758 | 2588 |
MYL9,SPC25,NF2,HOXB7,VANGL1,CTDSPL,TMX4,BLCAP,IL13RA1,BCL2L1,ISOC2,MGST2,PDGFB,BARD1,CARD10,CHST2,CDKN2C,CCND1,ST5,CCNA2,CTGF,OSBPL3,PHTF1,TACSTD2,PXMP4,TSPAN1,LOXL1,ZNF365,GM2A,SEPHS1,EBAG9,LOC81691,PSRC1,ERMP1,PTPN18,HN1L,USP18,SLC39A8,ARHGDIB,AURKB,LOXL2,ROR1,RAB38,ICMT,CD40,CCNF,CDK1,DAG1,GINS4,LCP1,PRIM1,TRAM2,ALDH5A1,CDCA4,STX10,PLK2,HOXA9,APBA2,NRGN,ISOC1,PPP2R2D,NUDT6,HJURP,CENPI,SOX9,ADO,CDCA3,EFHD2,TRMT2B,RSAD1,SSX2IP,SH2D4A,ICAM1,SAC3D1,M6PR,TOP2A,CTNNBIP1,TNS3,RAC2,MDM1,MLPH,CYR61,CTSC,CALD1,BDH1,FJX1,NEK2,KANK2,OSTF1,MDFIC,BUB1,MPHOSPH9,MCCC2,MED22,TMX1,AMOTL2,PIGC,HES1,ARAP2,SHMT1,KIF20A,PRSS23,FBXO9,ANTXR1,ZDHHC3,CYB5A,ENDOD1,FUCA1,NAAA,FAM64A,TIMM8A,NEIL3,DBI,E2F1,AGBL5,PGRMC1,AURKA,MAP3K5,TMEM14A |
| 1.768e-04 | -8.64 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | 176 | 44 | 17758 | 2588 |
KLF2,ZNF395,CKAP2,ASL,C6orf106,CALM3,RASGRP3,TRIB2,FAM46C,CDK14,CALM2,MARCH8,WEE1,ADD3,SP100,CD22,PLCG2,PIK3CA,CDKN1B,PIKFYVE,ATP2B1,SMAGP,TUBA4A,SYPL1,DDB2,HES1,CD55,KIAA0040,CALM1,EZR,EAF2,CASP4,RHOB,CD83,IRS2,BTG1,BANK1,SWAP70,WDR11,SIPA1L1,PIK3C2B,TTC9,TRAF5,DOCK9 |
| 1.768e-04 | -8.64 | GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | 176 | 44 | 17758 | 2588 |
MRC2,LGALS3,TSPAN15,INPP5D,EPHA4,EPS8,TMX4,PTTG1,ASL,MGST2,GALM,LMNA,GNS,CD109,CXCL16,UBE2T,SH3BP1,P4HB,PHTF1,PIKFYVE,C12orf75,SCYL3,TRIM62,ODF2L,PGM1,ELK3,ANO6,WHSC1,RUNX3,F12,CCNF,NPDC1,TXNDC11,C18orf8,FRMD4B,MMP17,PHLPP2,SETD3,NOD2,PLEKHG1,PITPNA,DONSON,POMT1,E2F8 |
| 1.771e-04 | -8.64 | STEIN_ESR1_TARGETS | MSigDB lists | STEIN_ESR1_TARGETS | 82 | 25 | 17758 | 2588 |
CCNE2,RECQL,PAPSS2,PRSS23,CELSR2,SLC39A8,MICB,TSC22D3,RET,ABCG4,FHL2,SOX13,BTG3,PCNA,NAB2,RAB31,SGK1,GLA,PXMP4,RAB27B,NCAPG2,TIAM1,TIPARP,SMC4,ABCG1 |
| 1.771e-04 | -8.64 | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR | MSigDB lists | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR | 82 | 25 | 17758 | 2588 |
CENPA,KIF20A,DLGAP5,MYBL2,CDCA8,RACGAP1,NUSAP1,FAM198B,KIF11,LBR,MAGOHB,CCNA2,UBE2T,FAM64A,CDCA5,RANBP1,E2F1,NEK2,KIF22,RTKN2,USP1,KNTC1,E2F8,SULF2,SEMA3B |
| 1.778e-04 | -8.63 | bone development | biological process | GO:0060348 | 162 | 42 | 16441 | 2455 |
INPPL1,RUNX2,PAPSS2,HSPG2,SOX9,RAB23,PHOSPHO1,OSR2,DHRS3,PLS3,PDGFA,BMP2,FAM20C,MEGF8,IMPAD1,TFAP2A,TWIST1,SP5,SULF2,CYP26B1,PDGFC,RHOA,ASXL1,ANO6,DCHS1,AMER1,PTGER4,WHSC1,FAM73B,PITX2,GNAS,FAT4,FGFR2,COL13A1,SEMA4D,NAB2,FGF18,CSGALNACT1,TRIM45,LRRK1,SHOX2,RARG |
| 1.778e-04 | -8.63 | negative regulation of neuron death | biological process | GO:1901215 | 162 | 42 | 16441 | 2455 |
GCLM,PINK1,CPEB4,GRIK2,TRAF2,SOD2,NES,BCL2L1,SIX4,TP73,CTNNB1,KIF14,MSH2,PIK3CA,BAX,PRKCI,SORL1,ERBB3,LGMN,F2R,SIRT1,SOD1,RHOA,AKT1,GCLC,OXR1,GRIN1,PPARA,ILK,RASA1,OPTN,MDK,FYN,HTT,BHLHB9,AXL,WFS1,NR4A3,CHMP4B,NR4A2,UNC5B,FAM134B |
| 1.785e-04 | -8.63 | SHC1 events in ERBB2 signaling | REACTOME pathways | R-HSA-1250196 | 228 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.785e-04 | -8.63 | GRB2 events in EGFR signaling | REACTOME pathways | R-HSA-179812 | 228 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.785e-04 | -8.63 | SHC1 events in EGFR signaling | REACTOME pathways | R-HSA-180336 | 228 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.785e-04 | -8.63 | SOS-mediated signalling | REACTOME pathways | R-HSA-112412 | 228 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.785e-04 | -8.63 | RAF/MAP kinase cascade | REACTOME pathways | R-HSA-5673001 | 228 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,DUSP5,FGF19,SPTB,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,CAMK2G,PSMA5,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,EGFR,RASA1,IRS2,FYN,JAK1,PPP2R5A,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,NRG1,SPTBN5,JAK3,PPP2R5D,PSMC1 |
| 1.785e-04 | -8.63 | GRB2 events in ERBB2 signaling | REACTOME pathways | R-HSA-1963640 | 228 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.785e-04 | -8.63 | SHC1 events in ERBB4 signaling | REACTOME pathways | R-HSA-1250347 | 228 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 1.787e-04 | -8.63 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP | 527 | 107 | 17758 | 2588 |
CCNC,LZTFL1,GRHL2,HOXB7,TUBB4B,DNAJC3,PPFIBP2,ETNK1,SOD2,TP53,KCTD12,CMTM6,SLC35E4,MOCS1,PICK1,DAPK2,NOV,CYP1A1,CTGF,SP100,METTL7A,LMO4,BCL6,IRF2,IFIT1,OAS3,RCAN3,LAMP3,SEMA3B,MX1,PPIF,GCA,TRIM8,KIFC2,CAPN6,USP18,SEPT6,ARFRP1,TRAM2,SHROOM3,PLK2,CORO1C,LRIG1,STAT1,IRF7,RBM43,HSPB1,LIFR,PARP12,TBC1D1,HLA-E,ARMC7,CDCA3,OSGIN2,INTS8,TRIB2,SEPP1,FAM21C,EFNB1,LGALS3BP,XPR1,CXCL16,PPP1R10,FAM160A2,ALG13,FJX1,TRIM21,SGK1,CASD1,RIMS2,TSPAN33,MCCC2,FAM134C,PARP9,ARAP2,SHMT1,ERMAP,MMD,PLSCR1,PRSS23,CRB3,BCL9,FAM73B,FNDC3A,IFIT3,ELK1,MEST,STEAP1,CDK5R1,FAS,PRDX4,KLHL2,IL1R1,CASP7,RND3,CSF1,OSMR,ERAP1,DONSON,LTBP2,OSR1,CMPK2,IFIH1,JAK3,AHR,IRF1,XDH |
| 1.790e-04 | -8.63 | V$CEBPB_02 | MSigDB lists | V$CEBPB_02 | 245 | 57 | 17758 | 2588 |
PLA2G4A,SPRED1,NCKAP5,BMF,MRC2,DYRK3,TTC39B,UGP2,THRA,NDRG1,PDCL,PDGFRL,PDGFB,DENND2D,TMPRSS4,SIRPA,CDKL5,LMO4,RRBP1,STEAP2,BCL6,CDKN1B,GYS1,GOT1,PDE4D,DUSP1,MAP3K3,SMARCA2,TGIF1,C6orf1,DCAF6,CASK,LONRF3,MOSPD2,CITED4,SERTAD4,RC3H2,BNIP3L,RAB3IP,ITPR3,PCTP,RHOB,LEMD2,PITX2,PRDX3,NFKBIA,RIN3,PPP1CB,EFNA5,NFKBIZ,SPRY4,ARF6,PRR15,TOB1,ARNT,CBX4,HOXC13 |
| 1.791e-04 | -8.63 | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | 197 | 48 | 17758 | 2588 |
CDS2,SCOC,LGALS3,IL15,S100A11,GNPDA1,TMEM41B,SERPINB9,PTTG1,EPS8,FLOT1,CRABP2,OAT,IL18R1,PLS3,CALR,AIM1,GTF2F2,BAX,TACSTD2,PIM1,PDIA6,S100A6,FAH,GCNT1,P2RX4,RFK,IFITM3,USP18,DSTN,RNF11,FURIN,GGH,NKAIN1,B3GALNT2,RNF19B,CASP4,RHOB,ATP13A2,SOCS3,IRX3,AHRR,GEM,TMEM159,ABCA1,KLF7,JARID2,EHD1 |
| 1.795e-04 | -8.63 | Kaposi_sarcoma | COSMIC cancer mutations | Kaposi_sarcoma | 27 | 12 | 17775 | 2585 |
TSC1,PLCG1,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR |
| 1.795e-04 | -8.63 | soft_tissue-blood_vessel-Kaposi_sarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-Kaposi_sarcoma | 27 | 12 | 17775 | 2585 |
TSC1,PLCG1,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR |
| 1.809e-04 | -8.62 | response to peptide hormone | biological process | GO:0043434 | 555 | 114 | 16441 | 2455 |
SPRED1,SORBS1,SLC2A4,SLC2A8,PSME2,WDTC1,NRG2,ERBB2,RASGRP3,PSME1,PRKACA,PDGFB,SPTB,GNB2,CALM2,PDGFA,ATP6V0B,SESN3,CCNA2,PSMD1,CTGF,SHC3,PSMC2,PIK3CA,CDKN1B,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,SIRT1,AKT1,ACVR1C,PRKAR2B,PRKCQ,POR,DAG1,RHEB,SOCS3,IRS2,ENPP1,IDE,FYN,JAK1,AREG,PSMD3,STAT1,CAB39,SLC27A1,EIF4EBP2,SPTBN5,NRG1,LTA4H,PSMC1,GAB1,RRAGD,PRKAR1A,PRKAA2,SORT1,INPPL1,RASA2,CTSB,PRKAA1,PSMD7,ATP6V1E2,CALM3,PSMD10,DUSP5,FGF19,HDAC9,TIMP1,IGF1R,BMP7,PRKCI,ERBB3,NCAM1,CAMK2G,MYO5A,PSMA5,GCNT1,RASGRF1,ADAM17,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,PPARA,STRADB,GGH,YES1,BCAR1,PSMA4,EGFR,RASA1,GPLD1,GNAS,TSC1,BTG1,INSR,PRKAG2,FGFR2,FGF18,RAB31,NR4A3,GRIN2D,NR4A2,GPER1,ATP6V1C1,JAK3,TBC1D4,CPEB2,DRD1 |
| 1.812e-04 | -8.62 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | 171 | 43 | 17758 | 2588 |
TRAPPC10,ARHGEF11,UBASH3B,NDRG1,TSC22D3,EPHA4,HABP4,NDC80,SNN,MXD1,SYTL2,H1FX,CAPN2,MARCH8,C16orf74,LLGL2,TAGLN2,MARCH2,PDE4D,SLC16A5,DUSP1,SUSD3,REC8,ITCH,DIAPH2,LDB2,FOS,TP53INP2,RASGRP2,SOCS3,IRS2,PTGS2,AREG,PELI2,CCDC69,FAM117A,ARRB1,PIEZO1,FHL1,MAFF,TOB1,FAM134B,PCSK5 |
| 1.832e-04 | -8.60 | RICKMAN_METASTASIS_UP | MSigDB lists | RICKMAN_METASTASIS_UP | 322 | 71 | 17758 | 2588 |
ACACB,ST13,ARMCX3,UPF3B,HEBP1,TMX4,DHX8,DNAJB11,APPBP2,ABCD4,PSMD1,TSPAN6,LMAN2L,PASK,ARMCX6,ETV4,COX11,SLC11A2,MRPS35,RAD17,IDH1,AMZ2,MFAP3L,GPRC5B,NGFRAP1,BHLHB9,ZNF704,RPL22,APBA2,LNP1,MRPL44,HJURP,ALDH6A1,GCAT,ATP9A,LRP4,ETV5,FAM134A,CDCA3,PSMD10,BEX2,PDXDC1,FGF19,CKAP5,PDIA4,RASSF8,MDM1,PAIP2B,MAGEE1,FAM13B,TPST1,SNED1,FARP2,ADAM17,SALL4,FAM133B,MEST,TCEAL8,GNAS,SEC14L4,PRCP,DCUN1D1,DTX4,PGRMC1,TCEAL4,SFMBT1,OSCP1,SH3BGRL2,GEM,ZBTB33,PHC1 |
| 1.832e-04 | -8.60 | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP | 27 | 12 | 17758 | 2588 |
CASP3,CDKN1C,ADO,TMX4,SAT1,TP53,PDCL,FBXL14,TRIM21,SRSF9,IRF1,CTH |
| 1.832e-04 | -8.60 | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | MSigDB lists | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | 27 | 12 | 17758 | 2588 |
MDK,CD99,MX1,KLK10,ALDH2,IFITM3,SOX9,STAT1,IRF7,IFIT1,CD81,IFI6 |
| 1.832e-04 | -8.60 | SHIN_B_CELL_LYMPHOMA_CLUSTER_7 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_7 | 27 | 12 | 17758 | 2588 |
RB1,IGF1R,CDKN1C,PTEN,STAT6,IL6ST,ZFP36,TEP1,BCL6,XRCC3,NOTCH3,RARG |
| 1.837e-04 | -8.60 | autonomic_ganglia-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-neuroblastoma | 4133 | 673 | 17775 | 2585 |
ACACB,ADD1,IBTK,GRIK2,AASS,AK7,PNPLA2,DNAJC3,RET,SMARCAL1,DHX8,FAM102B,BAIAP3,DPP8,SNX9,KIF26A,SLC35E4,GRM5,CALM2,CDKN2C,PHYHIP,PSMD1,RGS12,TGFBR3,MUC4,PPP1CA,WBP4,TIAM1,NWD1,SH3BGRL,SERTAD4,DSTN,KDELR3,MYOM1,PNKD,COL12A1,SLC44A3,ENPP1,PLCG1,TRIM47,MPRIP,WDR11,DNM1L,MYLK,FAM114A1,RNASEL,SCN5A,FAM169A,ITGA6,ZNRF3,MERTK,RABGGTA,FRY,CD22,RIMS3,MEGF8,ZIC5,FBXL14,SLAIN2,CADPS2,FAM84B,STT3B,MAPK7,ZMYM1,NCAM1,DGKG,NUP85,TTLL1,EPHX1,HPS3,SLC37A1,KIF20A,SALL4,STAT4,PLIN5,STK17A,CACHD1,NCOA3,SLC4A4,HTT,ITPR1,OSMR,DYSF,DRP2,ARPC2,TRPC3,RPS6KA3,XDH,DOCK9,WDR63,CCDC109B,GRHL2,NQO1,ACTR8,PKP2,IL13RA1,FAM91A1,MOCS1,UHRF1BP1L,MUC16,ST5,SP100,SH3BP1,DACT1,RAB27B,LRP11,CDKN2D,RNF169,ENPP4,SNX8,SSH3,LGALS8,SYNE2,CDCA2,SYP,TANC1,EBF2,PEX5,CCNB3,AXL,PNPLA6,ARNT,ISOC1,TNRC6C,PARP14,GMCL1,CTSZ,ZNF219,NUCB2,SLC25A43,TSPAN17,ICAM1,NEO1,ADD3,ARSG,FAM160A2,KNDC1,GPC3,CALD1,ALG13,TUBGCP6,WWP1,MAPK11,RAG1,CASD1,TPCN1,ACBD5,AMOTL2,ADAMTS2,PLSCR1,RAPGEF2,MFSD2B,PIK3R1,ELOVL3,CXorf57,PLEKHA7,RAB3IP,SNTB1,CNTNAP1,DCAF10,PITX2,PLOD2,CCDC6,ACVRL1,ZFP30,FOXA1,TLL2,TMEM131,UNKL,CUL4B,FHDC1,ARFGEF1,TEX2,HDAC6,SLC9A3R2,FANCI,SUSD2,ENTPD4,NUP210,CTNNB1,NPNT,SHC3,MKRN3,MITF,ABCA2,RGS5,TLN2,MYBL1,NEB,ZNF462,PLK1,ING1,CELSR2,EZR,CCBL2,CR2,IDH1,DZIP1L,DPYSL3,TNS4,PLEKHG6,MFAP3L,TRAM2,PLCH1,TBC1D17,MAP2,PIK3C2B,TTC39C,PRKAA2,ADCK5,CNTNAP2,DHRS3,FBLN1,MYO5C,TNS3,FRAS1,ICAM5,FCHO1,WNT3A,PLCB2,DPYSL5,WDR72,PLEKHA6,TESK1,SPATA13,KBTBD8,STRADB,SCRIB,PRX,MOSPD3,DHDH,MAPKAPK2,FA2H,COL13A1,CSF1,ITGA7,PRPS2,NLRC5,PLD1,ZDBF2,CDAN1,RNF146,USP43,NF2,DGKA,TP53,RHPN2,ERBB2,ZNF28,STIL,C1orf116,PDGFA,SRPX,WDR44,TACC2,PLCG2,PLK4,GYS1,NOTCH3,OAS3,FAR1,DVL2,CTH,CLCN3,AKT1,PTGER4,DAG1,PTGS2,DUOX1,TAPBP,IDE,C19orf66,ADAMTS14,ARHGAP4,NDST3,ZC3HC1,ZMAT1,CMAS,PACSIN2,GOLIM4,CPEB4,TAB3,MCTP2,HAL,ERCC6L,SLC9A2,NRP2,SIRPA,FZD6,DNAJB9,FOXP2,MAGEE1,FAM63A,IL17RA,SGK1,TSPAN13,ABCD1,ALDH7A1,SLC45A3,CAMK2G,TLE6,ATP2B1,MLEC,PLAUR,LITAF,MAML2,COL7A1,AKAP3,FXR2,CD83,USP6,FAT4,SCG2,NEIL3,NIPSNAP3A,CDCA7L,TMC5,FAM117A,ICOSLG,NDFIP1,UBE2C,HIPK3,ARHGEF9,ARHGEF4,GOLGB1,DIS3L,FAM171B,GAA,ACVR1,PPP4R4,HSPG2,SSH1,VANGL1,FAM129B,ATP8A1,PPFIBP2,C1orf198,PDGFRL,VASH1,CYP1A1,ANKS6,CTGF,OSBPL3,PRICKLE3,IL31RA,PIK3CA,KCNS3,AOX1,RCAN3,LAMP2,ORAI2,KIFC2,ACVR1C,CDYL,MGAM,KIF13A,CCNF,POR,SPNS3,RAB2B,ARHGEF26,AHRR,RBM47,BMP1,DHTKD1,SERPINI1,NFKBIZ,UNC5B,DDX58,SEMA6B,INPPL1,DHPS,TBC1D1,AKAP17A,NOTCH2,MESDC2,MECOM,DOPEY2,ITGA3,PIK3AP1,SLC16A6,AIM1,MSH2,PRKG1,SORL1,C8orf58,PIKFYVE,KCTD3,RIMS2,DNAI1,PIGC,DDB2,QSOX1,KCNJ12,FADS2,B3GNT7,KLK5,PRSS23,TBC1D8B,MICB,AMER1,DCHS1,PTPRH,PIP4K2C,PYGL,NPC2,ATP8B3,PKM,RASA1,STX3,FRMD4B,DGKH,AP1AR,NT5C2,SLCO4A1,PLEKHH2,TJP3,ISM1,DCK,SLC4A3,AGBL5,ARAP1,FAM83D,MPP2,FGD6,NR4A2,CABIN1,ZBTB34,PER3,IFIH1,PKD1L2,PLA2G4A,PLEKHG3,SLC2A4,CAPN12,CEP70,TRIP10,ST14,IQGAP1,CERCAM,RALBP1,ATP2C2,FAM78A,SNN,TMEM19,FLT3,AIFM2,ZFYVE9,ZNF75D,TRANK1,FICD,TNPO2,CNNM4,RNASEH2A,OSBPL7,PHKA2,NR2C1,MYO5B,DOCK4,COG2,TMEM43,FOXJ2,TEP1,UTRN,TMEM144,COX11,PRKCQ,SLC11A2,PYGO1,C15orf39,CBL,ITPR3,FZD7,AMZ2,DDOST,CCDC149,KIAA1804,STAT1,ZC3H12B,NR3C2,COBL,ATMIN,PLSCR4,SLC41A1,CENPI,NES,PLD2,DNAH3,PNPLA5,HLA-A,E2F7,FAM111A,RNF128,PTEN,MGAT1,ATP8B1,ERBB3,GFI1,TRIM62,OSGIN1,MSH6,NCOA2,PCCB,PDGFC,RASGRF1,ZWINT,ARAP2,PARP4,DIAPH2,FBXO9,ACADSB,FGFR2,TBX18,RIN3,AMMECR1,ABCB1,SERPINB5,PGM2L1,GRIN2D,ETAA1,FZD5,WDR62,CPEB2,ESPL1,MELK,OCLN,DEF6,JARID2,EXPH5,LTBP1,UGT8,TMEM184B,KIF2C,COMMD5,TMC1,CHPF,ABCD4,ARHGEF10L,SIPA1L2,HSF2,POF1B,ASH2L,MYH14,SLC39A10,MYRIP,RASGRP1,OLFML2A,TDP1,ASXL1,RGAG1,ARHGDIB,MRPS18A,MAN2A2,CXXC4,NEIL1,HPSE,FASTKD1,MADD,PSMC1,MIIP,CAPN1,PCSK5,SERPINE2,PPP1R12A,PEX6,PYROXD2,NOXA1,CES2,PFKL,OCRL,KCNN4,COL6A1,MTMR10,FNIP1,HLA-C,KNTC1,NCEH1,ZRANB1,LRIF1,ALS2CL,CCDC88A,KDELR1,PODXL2,PARD3B,OXR1,BTN3A2,VWA1,KIAA1109,HEATR5A,PRRC1,C3orf58,EGFR,MUM1L1,SOX13,GNAS,TSC1,ONECUT1,INSR,TMEM30A,RAB31,AFAP1,DRD1,KLF7,PROM2,LMO7,NCKAP5,PAX6,PDIA5,TDRKH,SLC25A48,SS18,ZNF687,KHNYN,FRYL,SMO,NFKB2,F2R,HSPA2,UPF3A,FRS3,SUSD3,GCA,MRPS35,DOCK5,FANCE,BFSP1,STAT6,TLE1,PLXND1,AKNA,SGOL1,MAD2L1BP,ABCA1,PPP2R2D,GLIS3,ARHGEF11,SHPRH,SH3D19,LRP4,TGFBR1,COL4A5,INTS8,SBF1,FAM167A,ITGA2B,TMEM63A,IRF2BPL,LLGL2,A4GALT,BMP7,ZDHHC13,KIAA0319,BRD7,TRIM3,ARVCF,RBMS2,MYO5A,ASPM,MBNL3,TTC7A,LEPR,MPV17L2,MAP1B,CD8A,PRCP,DTX4,GRAMD1C,HOXB13,AHR,L1CAM,NGEF,ZNF596,CD33 |
| 1.844e-04 | -8.60 | GCM_DLG1 | MSigDB lists | GCM_DLG1 | 73 | 23 | 17758 | 2588 |
SUN2,GPR107,RAPGEF2,FBXO9,KIAA1109,ERBB2IP,DNAJB14,NCS1,PLEKHB1,CCDC92,NAPG,GPRC5B,FRYL,IL6ST,PHLPP2,DDHD2,DLG1,SH3GLB2,NPTN,BTBD3,CAMK2G,NIPA1,TBC1D10B |
| 1.851e-04 | -8.59 | GSE17721_0.5H_VS_4H_POLYIC_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_4H_POLYIC_BMDM_DN | 192 | 47 | 17758 | 2588 |
CCNI,LZTFL1,MAN1A2,CUL4B,PDCL,TNFSF9,CKAP5,DOPEY2,PCNA,RPS6KA2,EFR3A,IL6ST,MITF,IRF2,IGFBP2,OSTF1,ASH2L,TECR,TIAM1,MYT1,C9orf72,GFPT1,MOSPD2,NR3C1,NUB1,PARP4,DBR1,PDK3,FXR2,SPTLC2,PSMA4,ABR,CNOT2,ENDOD1,CARHSP1,PPP2R5A,CCDC6,KBTBD2,CSF1,PLK2,ZDHHC20,NFKBIA,TDRD7,RAB31,RBM43,GLCCI1,HIPK3 |
| 1.851e-04 | -8.59 | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | 192 | 47 | 17758 | 2588 |
KIF3C,LGALS3,IQGAP1,DNAJC3,SERPINB9,TAP1,PPFIBP2,PDIA5,ASAH1,COL18A1,IL18,GDF15,FAM91A1,OAT,MERTK,FAM46C,SLC35E4,GNS,B3GALNT1,TYMP,OXCT1,P4HB,CD9,GYS1,CD70,RPN2,ECE1,NDUFA12,ITM2C,C9orf72,PSMA5,CKAP4,SOD1,PLSCR1,LAP3,UBAC1,CYFIP2,STX3,VCP,CMTM7,GLCE,AMZ2,CD8A,NUCB1,ACYP1,ATP1B3,TMEM159 |
| 1.858e-04 | -8.59 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | 51 | 18 | 17758 | 2588 |
AGRN,IGFBP6,RET,GATA3,ERBB2,RUNX3,SEPP1,SDC1,ALCAM,PDGFA,SPP1,TIMP3,TGFBR3,CDH1,IGF1R,BMP7,ITGAV,RARG |
| 1.873e-04 | -8.58 | oxidoreductase activity, acting on the aldehyde or oxo group of donors | molecular function | GO:0016903 | 46 | 17 | 16491 | 2452 |
ALDH2,ALDH6A1,OGDHL,MRPS36,PDHX,ALDH3B1,ALDH5A1,ALDH1A3,AOX1,DHTKD1,AKR1B1,ALDH7A1,FAR2,FAR1,ALDH3A2,DLAT,XDH |
| 1.879e-04 | -8.58 | YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta) | protein interactions | 7533 | 158 | 43 | 16036 | 2547 |
TNK1,THRA,FRMD6,DCAF7,KIF23,PDIA4,RASSF8,KIF5B,CDK16,ZFP36,PAK2,PIK3CA,KLC3,PRKCI,TUBG1,CDKN1B,ALDH7A1,PPP1CA,MAPK7,NCOA2,RIMS2,CCDC88A,MAP3K3,ING1,MARK1,ARHGEF28,NR3C1,CAPNS1,SAV1,CBL,CYFIP2,CDC25C,VCP,OPTN,NCOA3,TSC1,PIAS2,ARRB1,DMWD,MAP3K5,HSPB1,ISOC1,USP43 |
| 1.890e-04 | -8.57 | neuroblastoma | COSMIC cancer mutations | neuroblastoma | 4134 | 673 | 17775 | 2585 |
ACACB,ADD1,IBTK,GRIK2,AASS,AK7,PNPLA2,DNAJC3,RET,SMARCAL1,DHX8,FAM102B,BAIAP3,DPP8,SNX9,KIF26A,SLC35E4,GRM5,CALM2,CDKN2C,PHYHIP,PSMD1,RGS12,TGFBR3,MUC4,PPP1CA,WBP4,TIAM1,NWD1,SH3BGRL,SERTAD4,DSTN,KDELR3,MYOM1,PNKD,COL12A1,SLC44A3,ENPP1,PLCG1,TRIM47,MPRIP,WDR11,DNM1L,MYLK,FAM114A1,RNASEL,SCN5A,FAM169A,ITGA6,ZNRF3,MERTK,RABGGTA,FRY,CD22,RIMS3,MEGF8,ZIC5,FBXL14,SLAIN2,CADPS2,FAM84B,STT3B,MAPK7,ZMYM1,NCAM1,DGKG,NUP85,TTLL1,EPHX1,HPS3,SLC37A1,KIF20A,SALL4,STAT4,PLIN5,STK17A,CACHD1,NCOA3,SLC4A4,HTT,ITPR1,OSMR,DYSF,DRP2,ARPC2,TRPC3,RPS6KA3,XDH,DOCK9,WDR63,CCDC109B,GRHL2,NQO1,ACTR8,PKP2,IL13RA1,FAM91A1,MOCS1,UHRF1BP1L,MUC16,ST5,SP100,SH3BP1,DACT1,RAB27B,LRP11,CDKN2D,RNF169,ENPP4,SNX8,SSH3,LGALS8,SYNE2,CDCA2,SYP,TANC1,EBF2,PEX5,CCNB3,AXL,PNPLA6,ARNT,ISOC1,TNRC6C,PARP14,GMCL1,CTSZ,ZNF219,NUCB2,SLC25A43,TSPAN17,ICAM1,NEO1,ADD3,ARSG,FAM160A2,KNDC1,GPC3,CALD1,ALG13,TUBGCP6,WWP1,MAPK11,RAG1,CASD1,TPCN1,ACBD5,AMOTL2,ADAMTS2,PLSCR1,RAPGEF2,MFSD2B,PIK3R1,ELOVL3,CXorf57,PLEKHA7,RAB3IP,SNTB1,CNTNAP1,DCAF10,PITX2,PLOD2,CCDC6,ACVRL1,ZFP30,FOXA1,TLL2,TMEM131,UNKL,CUL4B,FHDC1,ARFGEF1,TEX2,HDAC6,SLC9A3R2,FANCI,SUSD2,ENTPD4,NUP210,CTNNB1,NPNT,SHC3,MKRN3,MITF,ABCA2,RGS5,TLN2,MYBL1,NEB,ZNF462,PLK1,ING1,CELSR2,EZR,CCBL2,CR2,IDH1,DZIP1L,DPYSL3,TNS4,PLEKHG6,MFAP3L,TRAM2,PLCH1,TBC1D17,MAP2,PIK3C2B,TTC39C,PRKAA2,ADCK5,CNTNAP2,DHRS3,FBLN1,MYO5C,TNS3,FRAS1,ICAM5,FCHO1,WNT3A,PLCB2,DPYSL5,WDR72,PLEKHA6,TESK1,SPATA13,KBTBD8,STRADB,SCRIB,PRX,MOSPD3,DHDH,MAPKAPK2,FA2H,COL13A1,CSF1,ITGA7,PRPS2,NLRC5,PLD1,ZDBF2,CDAN1,RNF146,USP43,NF2,DGKA,TP53,RHPN2,ERBB2,ZNF28,STIL,C1orf116,PDGFA,SRPX,WDR44,TACC2,PLCG2,PLK4,GYS1,NOTCH3,OAS3,FAR1,DVL2,CTH,CLCN3,AKT1,PTGER4,DAG1,PTGS2,DUOX1,TAPBP,IDE,C19orf66,ADAMTS14,ARHGAP4,NDST3,ZC3HC1,ZMAT1,CMAS,PACSIN2,GOLIM4,CPEB4,TAB3,MCTP2,HAL,ERCC6L,SLC9A2,NRP2,SIRPA,FZD6,DNAJB9,FOXP2,MAGEE1,FAM63A,IL17RA,SGK1,TSPAN13,ABCD1,ALDH7A1,SLC45A3,CAMK2G,TLE6,ATP2B1,MLEC,PLAUR,LITAF,MAML2,COL7A1,AKAP3,FXR2,CD83,USP6,FAT4,SCG2,NEIL3,NIPSNAP3A,CDCA7L,TMC5,FAM117A,ICOSLG,NDFIP1,UBE2C,HIPK3,ARHGEF9,ARHGEF4,GOLGB1,DIS3L,FAM171B,GAA,ACVR1,PPP4R4,HSPG2,SSH1,VANGL1,FAM129B,ATP8A1,PPFIBP2,C1orf198,PDGFRL,VASH1,CYP1A1,ANKS6,CTGF,OSBPL3,PRICKLE3,IL31RA,PIK3CA,KCNS3,AOX1,RCAN3,LAMP2,ORAI2,KIFC2,ACVR1C,CDYL,MGAM,KIF13A,CCNF,POR,SPNS3,RAB2B,ARHGEF26,AHRR,RBM47,BMP1,DHTKD1,SERPINI1,NFKBIZ,UNC5B,DDX58,SEMA6B,INPPL1,DHPS,TBC1D1,AKAP17A,NOTCH2,MESDC2,MECOM,DOPEY2,ITGA3,PIK3AP1,SLC16A6,AIM1,MSH2,PRKG1,SORL1,C8orf58,PIKFYVE,KCTD3,RIMS2,DNAI1,PIGC,DDB2,QSOX1,KCNJ12,FADS2,B3GNT7,KLK5,PRSS23,TBC1D8B,MICB,AMER1,DCHS1,PTPRH,PIP4K2C,PYGL,NPC2,ATP8B3,PKM,RASA1,STX3,FRMD4B,DGKH,AP1AR,NT5C2,SLCO4A1,PLEKHH2,TJP3,ISM1,DCK,SLC4A3,AGBL5,ARAP1,FAM83D,MPP2,FGD6,NR4A2,CABIN1,ZBTB34,PER3,IFIH1,PKD1L2,PLA2G4A,PLEKHG3,SLC2A4,CAPN12,CEP70,TRIP10,ST14,IQGAP1,CERCAM,RALBP1,ATP2C2,FAM78A,SNN,TMEM19,FLT3,AIFM2,ZFYVE9,ZNF75D,TRANK1,FICD,TNPO2,CNNM4,RNASEH2A,OSBPL7,PHKA2,NR2C1,MYO5B,DOCK4,COG2,TMEM43,FOXJ2,TEP1,UTRN,TMEM144,COX11,PRKCQ,SLC11A2,PYGO1,C15orf39,CBL,ITPR3,FZD7,AMZ2,DDOST,CCDC149,KIAA1804,STAT1,ZC3H12B,NR3C2,COBL,ATMIN,PLSCR4,SLC41A1,CENPI,NES,PLD2,DNAH3,PNPLA5,HLA-A,E2F7,FAM111A,RNF128,PTEN,MGAT1,ATP8B1,ERBB3,GFI1,TRIM62,OSGIN1,MSH6,NCOA2,PCCB,PDGFC,RASGRF1,ZWINT,ARAP2,PARP4,DIAPH2,FBXO9,ACADSB,FGFR2,TBX18,RIN3,AMMECR1,ABCB1,SERPINB5,PGM2L1,GRIN2D,ETAA1,FZD5,WDR62,CPEB2,ESPL1,MELK,OCLN,DEF6,JARID2,EXPH5,LTBP1,UGT8,TMEM184B,KIF2C,COMMD5,TMC1,CHPF,ABCD4,ARHGEF10L,SIPA1L2,HSF2,POF1B,ASH2L,MYH14,SLC39A10,MYRIP,RASGRP1,OLFML2A,TDP1,ASXL1,RGAG1,ARHGDIB,MRPS18A,MAN2A2,CXXC4,NEIL1,HPSE,FASTKD1,MADD,PSMC1,MIIP,CAPN1,PCSK5,SERPINE2,PPP1R12A,PEX6,PYROXD2,NOXA1,CES2,PFKL,OCRL,KCNN4,COL6A1,MTMR10,FNIP1,HLA-C,KNTC1,NCEH1,ZRANB1,LRIF1,ALS2CL,CCDC88A,KDELR1,PODXL2,PARD3B,OXR1,BTN3A2,VWA1,KIAA1109,HEATR5A,PRRC1,C3orf58,EGFR,MUM1L1,SOX13,GNAS,TSC1,ONECUT1,INSR,TMEM30A,RAB31,AFAP1,DRD1,KLF7,PROM2,LMO7,NCKAP5,PAX6,PDIA5,TDRKH,SLC25A48,SS18,ZNF687,KHNYN,FRYL,SMO,NFKB2,F2R,HSPA2,UPF3A,FRS3,SUSD3,GCA,MRPS35,DOCK5,FANCE,BFSP1,STAT6,TLE1,PLXND1,AKNA,SGOL1,MAD2L1BP,ABCA1,PPP2R2D,GLIS3,ARHGEF11,SHPRH,SH3D19,LRP4,TGFBR1,COL4A5,INTS8,SBF1,FAM167A,ITGA2B,TMEM63A,IRF2BPL,LLGL2,A4GALT,BMP7,ZDHHC13,KIAA0319,BRD7,TRIM3,ARVCF,RBMS2,MYO5A,ASPM,MBNL3,TTC7A,LEPR,MPV17L2,MAP1B,CD8A,PRCP,DTX4,GRAMD1C,HOXB13,AHR,L1CAM,NGEF,ZNF596,CD33 |
| 1.890e-04 | -8.57 | regulation of protein localization | biological process | GO:0032880 | 906 | 174 | 16441 | 2455 |
EXPH5,TXN,LGR4,TRIM5,CACNA2D2,GATA3,IL18,ITPR2,SYTL4,CCNB1,HDAC6,BARD1,ERP29,SLC8B1,CTNNB1,CABP1,KCNS3,DLG1,MYRIP,RASGRP1,VPS11,TRIM8,CELSR2,ACVR1C,BNIP3L,NBPF3,EZR,PRKAR2B,SLC25A5,CDK1,LCP1,SLC25A4,DNM1L,RAB11FIP1,NOD2,ARF6,F2RL1,DDX58,BMF,NFKBIE,TBC1D1,HLA-E,RAB23,RACGAP1,NCKAP1,FBLN1,IL18R1,ANO1,LMNA,RB1,RAC2,ITGA3,PFKL,KCNN4,NEK2,PRKCI,SORL1,MDFIC,CACNA1D,WNT3A,MAPK7,MDFI,EPB41L5,GCC2,MMD,WHSC1,PLS1,KIF20B,TP53INP2,EGFR,STX3,CDK5R1,GNAS,TMEM30A,NFKBIA,CDCA5,ITPR1,OSCP1,YOD1,TMEM173,LZTFL1,SORBS1,NF2,THRA,IQGAP1,TP53,ERBB2,P2RX7,CD274,BCL2L1,MICALL2,PRKACA,APC2,BCAP31,ARHGEF16,PER2,NOV,CDH1,SP100,RALB,DACT1,SMO,TAX1BP3,DAB2IP,TWIST1,MYT1,F2R,TMBIM1,CHP1,SIRT1,BAG4,ERLEC1,AKT1,PFKFB2,DMTN,PTGER4,PRKCQ,ITPR3,CD40,SNX12,FZD7,IRS2,PTGS2,FYN,STX10,PPP2R5A,WWTR1,NRG1,RAB29,EFNA5,PRKAR1A,TCAF1,PINK1,TRAF2,PSMD10,TGFBR1,HMGN3,SIX4,WWP2,NEO1,KIF5B,CARD8,OXCT1,CDK16,LLGL2,BMP7,FAM20B,UBE2J1,TMBIM6,MAPK11,SYK,HES1,RHOA,PIK3R1,SYBU,LITAF,RGCC,VAMP3,PIM3,BORA,GPLD1,NUCB1,LDLRAP1,BANK1,SWAP70,SYT7,E2F1,ARRB1,PKD2,SPCS3,GPER1,FZD5,NDFIP1,PKIA |
| 1.891e-04 | -8.57 | dermatofibrosarcoma_protuberans | COSMIC cancer mutations | dermatofibrosarcoma_protuberans | 20 | 10 | 17775 | 2585 |
SS18,ACAP2,PTEN,MSH2,IDH1,CARD10,ZFYVE9,EGFR,PAQR7,SH3RF2 |
| 1.891e-04 | -8.57 | soft_tissue-fibrous_tissue_and_uncertain_origin-dermatofibrosarcoma_protuberans | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-dermatofibrosarcoma_protuberans | 20 | 10 | 17775 | 2585 |
SS18,ACAP2,PTEN,MSH2,IDH1,CARD10,ZFYVE9,EGFR,PAQR7,SH3RF2 |
| 1.901e-04 | -8.57 | ITGB1 (integrin beta 1) | protein interactions | 3688 | 98 | 30 | 16036 | 2547 |
TIMP2,LGALS3,NF2,HSPG2,LGALS8,CD63,PLAUR,CD82,DSTN,ITGA6,EPS8,FBXO2,FHL2,PDIA3,TGOLN2,FBXO6,ILK,FBLN1,DAG1,RANBP9,LGALS3BP,VCP,CD46,SPP1,ITGA3,IGF1R,ITGA7,CD9,ITGAV,CD81 |
| 1.902e-04 | -8.57 | heparan sulfate proteoglycan biosynthetic process | biological process | GO:0015012 | 23 | 11 | 16441 | 2455 |
B3GALT6,HS6ST1,XYLT2,XYLT1,CSGALNACT1,HS3ST3B1,DSE,EXT2,NDST3,HS6ST3,GLCE |
| 1.902e-04 | -8.57 | SASSON_RESPONSE_TO_FORSKOLIN_UP | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_UP | 87 | 26 | 17758 | 2588 |
CD55,CASP9,BNIP3L,COL18A1,EZR,MAP1LC3B,RHOB,GNAS,PSMD1,GPRC5B,CDK16,GDE1,P4HA2,ITPR1,FDXR,PGRMC1,SGK1,TMBIM6,PDXK,MAP3K5,PLIN3,PHKA2,MAP3K7,ATP2B1,DUSP1,PRKAR1A |
| 1.911e-04 | -8.56 | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | 187 | 46 | 17758 | 2588 |
UNC93B1,SPRED1,SORT1,BLVRB,HAL,ASAH1,FTH1,CTSZ,NOTCH2,TMEM170B,SNN,GSTP1,ADAMTSL4,TTYH3,BMP2K,MXD1,HDAC9,APLP2,CD9,DAPK1,H2AFY,RAB20,PTPRE,C9orf72,SYK,CCDC88A,PDGFC,PLSCR1,BNIP3L,PRKAR2B,C15orf39,PCTP,ADRBK2,TP53I3,CRISPLD2,INSR,WDR11,PRCP,CORO1C,SLC2A6,DGAT2,ZDHHC7,DYSF,ARSB,LTA4H,SLC31A2 |
| 1.911e-04 | -8.56 | MODULE_244 | MSigDB lists | MODULE_244 | 187 | 46 | 17758 | 2588 |
DYRK3,ACVR1,PEX6,EPHA4,KIF23,MAPK4,KIF2C,PKN1,MERTK,TOP2A,WEE1,PCNA,IGF1R,IRAK1,CDK16,KIF14,GTF2F2,PLK4,MSH2,PRKCI,NEK2,KIF22,BUB1,ABCC1,SEPHS1,NEK4,PLK1,SMARCA2,MAPKAPK3,AK4,PRKCQ,RUNX3,PDK3,KIF11,CDK1,DDX23,PRIM1,DCK,PTK7,LIMK1,STK38,MYLK,XRCC3,MAPK13,CENPE,MELK |
| 1.911e-04 | -8.56 | ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 187 | 46 | 17758 | 2588 |
NFKBIE,PEX6,GGA1,PDIA3,APBA1,ERP29,BARD1,AIP,ZFYVE9,APPBP2,PDIA4,ATG4A,CALR,ZFYVE16,CARD8,AP1M2,CDH1,PPP1R10,LMAN2L,KIF13B,REEP1,BCL6,ARL4D,F2R,TRAM1,RPGR,KDELR1,ATG4D,MDFI,NAGPA,AKT1,COG2,STRADB,ICMT,VCP,EGFR,OPTN,KLHL2,SCG2,NOD2,ARFGAP3,CTSA,KPNA2,LTBP2,ABCA1,ABCG1 |
| 1.911e-04 | -8.56 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP | 187 | 46 | 17758 | 2588 |
LAMP1,RUNX2,HSP90B1,CRYM,SEC61G,HERC5,TEX2,PLA2G16,NUCB2,SLC20A1,DUSP5,PDIA4,DAPK2,RAB15,BTG3,ENTPD4,RPS6KA2,TM9SF2,DACT1,MGAT4A,RRBP1,UBE2J1,MDFIC,TSPAN13,MARCH2,EGLN3,GFI1,ITM2C,SEPHS1,SEC61B,GGH,NPC2,CYFIP2,LHFPL2,C18orf8,CDK5R1,ATP13A2,MAPKAPK2,SCARB2,ALDH5A1,DCK,PTK7,WDR19,IRF7,FHL1,TBC1D4 |
| 1.911e-04 | -8.56 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN | 187 | 46 | 17758 | 2588 |
CASP3,HJURP,SDC4,HEXB,TAP1,ETNK1,BARD1,FANCI,TOP2A,APOBEC3B,WEE1,PCNA,PSMD1,PHTF1,PSMC2,PRC1,HSPA13,KNTC1,MINPP1,GFI1,TMED2,PSMA5,SMC4,TBC1D10B,FADS2,DDB2,SEC61B,PSRC1,MLEC,STAU2,CDC20,GLO1,CCNF,IDH1,FRMD4B,ZMPSTE24,GALNT3,KCNK1,GDE1,RBL1,NAT1,ITPR1,PPP2R3C,MAD2L1BP,CCNB2,ESPL1 |
| 1.926e-04 | -8.55 | TOMLINS_METASTASIS_DN | MSigDB lists | TOMLINS_METASTASIS_DN | 20 | 10 | 17758 | 2588 |
TMEM50B,TMEM87B,TM9SF2,PVRL2,TMEM98,UBE2J1,KDELR3,CTSZ,MESDC2,TMEM131 |
| 1.926e-04 | -8.55 | GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN | 156 | 40 | 17758 | 2588 |
GRN,ARHGEF11,S100A11,ETV5,STRN4,HERC5,CALM3,HERC6,LGALS3BP,HLA-A,SIRPA,CALM2,CALR,ZYX,CDK16,PAK2,H2AFY,ABCD1,TAGLN2,IFIT1,OAS3,CTSD,KDELR1,TBC1D10B,MX1,PLSCR1,IFITM3,USP18,CALM1,EMP3,IFIT3,RNF19B,GNAS,NUCB1,MID1IP1,HPSE,H1F0,NMI,IFI6,ARNT |
| 1.929e-04 | -8.55 | membrane raft | cellular component | GO:0045121 | 271 | 62 | 17570 | 2579 |
CASP3,SPRED1,SCN5A,SORBS1,SLC2A4,PACSIN2,NF2,CTSB,TRAF2,RET,SDC4,LRP4,FLOT1,EFHD2,ERBB2,HDAC6,PRKACA,EMP2,EFNB1,ICAM1,CAPN2,CDH1,IGF1R,CTNNB1,KCNN4,DLG1,SMO,TRPC1,PIKFYVE,CTSD,FLOT2,F2R,CD55,ADAM17,PLSCR1,RGMB,FURIN,EZR,PRKAR2B,ATP1B1,CBL,DAG1,EGFR,FAS,BCL10,PTGS2,ATP1A1,RTN4RL1,INSR,FYN,HPSE,CORO1C,PRKCDBP,SLC27A1,EFNA5,MAL2,ATP1B3,UNC5B,ABCA1,PROM2,PRKAR1A,DRD1 |
| 1.930e-04 | -8.55 | haematopoietic_and_lymphoid_tissue-pharynx-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-pharynx-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | 47 | 17 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CTNNB1,CDH1,PTEN,FGFR2,SMO,PIK3CA,JAK3 |
| 1.935e-04 | -8.55 | MODULE_53 | MSigDB lists | MODULE_53 | 390 | 83 | 17758 | 2588 |
PAX6,DLGAP5,EPAS1,FOXM1,S100A11,PTTG1,TAP1,NDC80,C5orf30,NRG2,KIF2C,CCNB1,CARD10,CHPF,IER3,CDKN2C,DAPK2,WEE1,ZYX,PCNA,CCNA2,ARTN,SH3BP1,TACC2,KIF14,FOSB,IFIT1,RNASEH2A,CKS2,CYP1B1,PLK1,VPS11,CENPA,PFKFB2,S100A4,CDC20,ARHGDIB,PKMYT1,CCNF,CDK1,LCP1,PRIM1,MDK,PAFAH1B3,TBX1,GLA,ARHGAP4,ABCA1,MAPK12,ENO2,BIK,DUSP5,SAC3D1,M6PR,CKAP5,TOP2A,RAC2,CTSC,CD22,KCNN4,MSH2,IGFBP2,KNTC1,TMX1,MSH6,HMMR,QSOX1,FADS2,ZWINT,WNT10B,MYBL2,EMP3,GGH,POLD3,KIF11,FOS,SWAP70,ETS2,RAB31,E2F1,CCNB2,UBE2C,CD33 |
| 1.935e-04 | -8.55 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN | 499 | 102 | 17758 | 2588 |
MTM1,PNISR,ST13,FOXM1,SUZ12,ATP8A1,SLC25A13,EPHA4,TMX4,XIAP,PJA2,FAM46C,CHST2,RNF220,CNTRL,LMO4,IL6ST,KLF3,SLC44A1,CTTN,TMEM64,SLC39A10,F2R,CTDSP2,SEC23A,TIMP2,CITED4,RFK,CAPN6,AGPS,SLC39A8,CASP9,UTRN,PRKAR2B,ERBB2IP,CBL,ZFAND5,SLC25A5,ALCAM,SP4,LCP1,DPYSL3,MSL1,SHROOM3,EFNA5,SLC31A2,ARNT,RMND5A,LASP1,SH3D19,ABCG2,C6orf106,EFHD2,PBX3,TGFBR1,ETS1,MECOM,SGPL1,IRF2BPL,ADD3,CA2,PTEN,CTSC,FLRT3,PPP4R1,PRC1,PRKCI,BUB1,KANK2,PIM1,AK3,CNOT6L,ALDH3A2,PPP6R1,CKAP4,ATP2B1,HP1BP3,TRAK2,FADS2,PHF20L1,UFD1L,ERMAP,PIK3R1,HMG20B,KCTD20,FAM109A,PCTP,KIF11,MAP1B,MAPKAPK2,PITX2,SERPINA1,DGCR2,RCBTB2,TWSG1,FGFR2,ALG2,FZD5,CBX5,SHOX2,HIPK3,USP16 |
| 1.944e-04 | -8.55 | SCN4A (sodium channel, voltage gated, type IV alpha subunit) | protein interactions | 6329 | 10 | 7 | 16036 | 2547 |
SNTA1,ERBB2IP,DLG3,SNTB1,SNTB2,CALM1,DLG1 |
| 1.956e-04 | -8.54 | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | 151 | 39 | 17758 | 2588 |
CASP3,MTM1,ST14,SDC4,BIK,IL18,BAIAP3,GALM,PATL2,PHLPP1,FAM81A,IL18R1,SYTL2,NEO1,HDAC9,EPCAM,TGFBR3,ITGB8,ABCA2,LGMN,TMBIM1,S100A6,EPHX1,TGIF1,MBP,FAM160A1,ITCH,USP18,S100A4,TCF7,PNKD,SP4,GABARAPL1,PTPRJ,JAK1,UAP1,MATN2,DGAT2,CBX7 |
| 1.963e-04 | -8.54 | transmembrane receptor protein kinase activity | molecular function | GO:0019199 | 81 | 25 | 16491 | 2452 |
LTBP1,ACVR1,ACVR1C,EPHA4,RET,ERBB2,TGFBR1,PDGFRL,ROR1,EPHA1,MERTK,DDR1,FLT3,EGFR,NRP2,EPHA10,INSR,TGFBR3,IGF1R,ACVRL1,FGFR2,AXL,RYK,EPHB4,NPTN |
| 1.972e-04 | -8.53 | midbody | cellular component | GO:0030496 | 130 | 35 | 17570 | 2579 |
HSP90B1,SSH1,KLHL13,IQGAP1,CDCA8,KIF23,RACGAP1,TXNDC9,PKN1,RALB,KIF14,PRC1,NEK2,DNM2,CAPG,PLK1,RHOA,PSRC1,KIF20A,SEPT6,ASPM,VPS4B,KIF13A,KIF20B,AURKB,CDK1,TRIOBP,AGBL5,AURKA,CTNND1,CHMP4B,CENPE,GEM,ARF6,ANXA11 |
| 1.981e-04 | -8.53 | GNF2_HLA-C | MSigDB lists | GNF2_HLA-C | 47 | 17 | 17758 | 2588 |
HLA-E,TSC22D3,INPP5D,HLA-F,TAP1,ARHGDIB,GRK6,HLA-A,HLA-B,RAC2,TAPBP,STAT6,RIN3,FXYD5,HLA-C,ARF6,IRF1 |
| 1.993e-04 | -8.52 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | 121 | 33 | 17758 | 2588 |
CTSB,ITGA6,PHLDA1,CCND1,TOP2A,SPP1,PCNA,TIMP1,KCNN4,FUT8,PLK4,CKS1B,AHCY,NCAM1,ETV4,TIPARP,SLC12A2,ZWINT,CENPA,CASK,PLSCR1,FIGNL1,GTF2A2,CASP4,RASA1,RBL1,AREG,FAM3C,NFKBIA,UBE2D2,AURKA,E2F8,NGEF |
| 1.999e-04 | -8.52 | REACTOME_APOPTOSIS | MSigDB lists | REACTOME_APOPTOSIS | 141 | 37 | 17758 | 2588 |
CASP3,BMF,ADD1,PSME2,TRAF2,XIAP,TP53,PSMD7,PSMD10,PSME1,BCL2L1,BCAP31,LMNA,DAPK2,PSMD1,CTNNB1,CDH1,PAK2,PSMC2,DAPK1,BAX,PSMA5,PSMB4,AKT1,CASP9,PRKCQ,PSMA4,FAS,CASP7,FNTA,H1F0,DNM1L,PSMD3,E2F1,UNC5B,PSMC1,OCLN |
| 2.004e-04 | -8.52 | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | MSigDB lists | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | 459 | 95 | 17758 | 2588 |
HECA,TRIM2,GRIK2,EPHA4,CTDSPL,CACNA2D2,RNF182,MPP5,EGR3,SNN,PHLDA1,GRM5,PER2,CPNE2,INPP5E,ACAP2,DPYSL2,OSBPL3,ARNT2,EPB41L4B,PDIA6,BTBD3,MAP3K3,CPD,SIRT1,THRB,PTPN9,CDYL,ATP1B1,IRS2,TRIM9,PIAS3,PI4K2B,HLF,RBM47,SLC9A6,PPP1CB,SPRY4,CBX7,CBX4,MAMDC2,NR2C2,CPEB4,SCOC,TAB3,TBC1D1,PLEKHJ1,ARHGEF7,ADO,PBX3,CNTNAP2,ETS1,NFAT5,ANO1,LBR,DUSP5,SSX2IP,IRF2BPL,E2F7,ITGA3,ITGB8,ADRBK1,CYR61,FAM160A2,FAM13B,TRIM3,NPTN,NPTXR,NCOA2,CAMK2G,ATP2B1,TRAK2,PHF20L1,NR3C1,ZC3H11A,C2orf69,PLS1,FAM73B,FNDC3A,FOS,NMT2,MAP1B,KLHL2,TIMP3,RAB11FIP2,CSNK1G1,FAM3C,NR4A3,DCUN1D1,ZDHHC7,TBC1D4,COL16A1,RPS6KA3,RAD21,RGMA |
| 2.005e-04 | -8.51 | GTACTGT,MIR-101 | MSigDB lists | GTACTGT,MIR-101 | 246 | 57 | 17758 | 2588 |
SPRED1,LRRFIP2,SOX9,ETV5,PRKAA1,UBE2Q1,TGFBR1,FAM78A,POMGNT1,PHLDA1,SIX4,TEAD3,ZNF385B,MXD1,FZD6,SGPL1,FLRT3,USP38,SEMA3G,PDE4D,SLC39A10,BTBD3,MYRIP,CERS2,SOCS5,DUSP1,MOB4,THRB,PHF20L1,CLCN3,MLEC,MARK1,FZD4,BCL9,CDYL,UBE2A,KBTBD8,ERP44,ERBB2IP,SRSF5,CBL,FOS,DAG1,C3orf58,RANBP9,CDK5R1,USP6,MMP15,PTGS2,PLCG1,RAP2C,UBE2D2,PIK3C2B,PIEZO1,NDFIP1,MIIP,CPEB2 |
| 2.009e-04 | -8.51 | KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | MSigDB lists | KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | 126 | 34 | 17758 | 2588 |
SORT1,NFKBIE,RPS6KA1,TP53,CALM3,TP73,CALM2,RPS6KA2,IRAK1,SHC3,PLCG2,BAX,PIK3CA,MAPK11,PIK3CD,MAPK7,CAMK2G,MAP3K3,RHOA,RIPK2,AKT1,PIK3R1,CALM1,ARHGDIB,IRS2,MAPKAPK2,PLCG1,NGFRAP1,NFKBIA,MAPK13,MAP3K5,GAB1,RPS6KA3,MAPK12 |
| 2.014e-04 | -8.51 | FRS-mediated FGFR1 signaling | REACTOME pathways | R-HSA-5654693 | 229 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 2.014e-04 | -8.51 | FRS-mediated FGFR2 signaling | REACTOME pathways | R-HSA-5654700 | 229 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 2.014e-04 | -8.51 | FRS-mediated FGFR4 signaling | REACTOME pathways | R-HSA-5654712 | 229 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 2.014e-04 | -8.51 | FRS-mediated FGFR3 signaling | REACTOME pathways | R-HSA-5654706 | 229 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 2.021e-04 | -8.51 | embryonic placenta development | biological process | GO:0001892 | 90 | 27 | 16441 | 2455 |
HES1,GRHL2,CDKN1C,AKT1,EPAS1,ST14,PLAC1,PDGFB,EGFR,SOCS3,HS6ST1,E2F7,NCOA3,CYR61,FGFR2,GATA2,SPINT2,PLK4,PKD2,FZD5,TTPA,E2F8,GAB1,ARNT,TMED2,MDFI,EGLN1 |
| 2.035e-04 | -8.50 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | 198 | 48 | 17758 | 2588 |
GRN,SPRED1,CDS2,ACVR1,IQGAP1,UBASH3B,TMX4,FBXO2,CACNA2D2,SMARCAL1,ASAH1,FAM102B,PBX3,TGFBR1,CNTROB,DDR1,FAM46C,BMP2K,CTNNB1,TIMP1,TACC2,OSBPL3,MGAT4A,TOX2,SGK1,TSPAN13,KLF9,CTTN,CASD1,TIAM1,ALDH3A2,MGAT5,TMED2,ELK3,GCLC,SLC39A8,PIK3R1,EAF2,FNDC3A,MAGED2,PGF,PLCG1,MSL1,HTT,TMEM30A,CSGALNACT1,CENPE,PHC1 |
| 2.039e-04 | -8.50 | V$EGR1_01 | MSigDB lists | V$EGR1_01 | 257 | 59 | 17758 | 2588 |
SPRED1,CMAS,PCOLCE,CDK17,PACSIN2,KCNAB3,MRC2,CEP70,UBASH3B,EGR3,MORF4L2,BAHD1,PDGFB,PRKACA,GNB2,SPTB,SH3KBP1,XPR1,SLC9A7,IRF2BPL,CDKN2C,FOXP2,APLP2,RALGPS2,ITGB8,SH3BP1,WDR44,ARL1,ICAM5,KLF3,CNNM4,TNFRSF12A,USP1,CNOT6L,RASGEF1A,SMYD5,C12orf75,DLX4,ETV4,C9orf72,DVL2,SOCS5,RHOA,KREMEN2,GRIN1,CLSTN1,TFAP2C,RHOB,CRTC2,MAN2A2,CORO1C,NAB2,PITPNA,HMGA1,PLOD3,SLC25A38,STARD13,NRGN,RPS6KA3 |
| 2.052e-04 | -8.49 | autonomic_ganglia | COSMIC cancer mutations | autonomic_ganglia | 4170 | 678 | 17775 | 2585 |
ACACB,ADD1,IBTK,GRIK2,AASS,AK7,PNPLA2,DNAJC3,RET,SMARCAL1,DHX8,FAM102B,BAIAP3,DPP8,SNX9,KIF26A,SLC35E4,GRM5,CALM2,CDKN2C,PHYHIP,PSMD1,RGS12,TGFBR3,MUC4,PPP1CA,WBP4,TIAM1,NWD1,SH3BGRL,SERTAD4,DSTN,KDELR3,MYOM1,PNKD,COL12A1,SLC44A3,ENPP1,PLCG1,TRIM47,MPRIP,WDR11,DNM1L,MYLK,FAM114A1,RNASEL,SCN5A,FAM169A,ITGA6,ZNRF3,MERTK,RABGGTA,FRY,CD22,RIMS3,MEGF8,ZIC5,FBXL14,SLAIN2,CADPS2,FAM84B,STT3B,MAPK7,ZMYM1,NCAM1,DGKG,NUP85,TTLL1,EPHX1,HPS3,SLC37A1,KIF20A,SALL4,STAT4,PLIN5,STK17A,CACHD1,NCOA3,SLC4A4,HTT,ITPR1,OSMR,DYSF,DRP2,ARPC2,TRPC3,RPS6KA3,XDH,DOCK9,WDR63,CCDC109B,GRHL2,NQO1,ACTR8,PKP2,IL13RA1,FAM91A1,MOCS1,UHRF1BP1L,MUC16,ST5,SP100,SH3BP1,DACT1,RAB27B,LRP11,CDKN2D,RNF169,ENPP4,SNX8,SSH3,LGALS8,SYNE2,CDCA2,SYP,TANC1,EBF2,PEX5,CCNB3,AXL,PNPLA6,ARNT,ISOC1,TNRC6C,PARP14,GMCL1,CTSZ,ZNF219,NUCB2,SLC25A43,TSPAN17,ICAM1,NEO1,ADD3,ARSG,FAM160A2,KNDC1,GPC3,CALD1,ALG13,TUBGCP6,WWP1,ZNF230,MAPK11,RAG1,CASD1,TPCN1,ACBD5,AMOTL2,ADAMTS2,PLSCR1,RAPGEF2,MFSD2B,PIK3R1,ELOVL3,CXorf57,PLEKHA7,RAB3IP,SNTB1,CNTNAP1,DCAF10,PITX2,PLOD2,CCDC6,ACVRL1,ZFP30,FOXA1,TLL2,TMEM131,UNKL,CUL4B,FHDC1,ARFGEF1,TEX2,HDAC6,SLC9A3R2,FANCI,SUSD2,ENTPD4,NUP210,CTNNB1,NPNT,SHC3,MKRN3,MITF,ABCA2,RGS5,TLN2,MYBL1,NEB,ZNF462,PLK1,ING1,CELSR2,EZR,CCBL2,CR2,IDH1,DZIP1L,DPYSL3,TNS4,PLEKHG6,MFAP3L,TRAM2,PLCH1,TBC1D17,MAP2,PIK3C2B,TTC39C,PRKAA2,ADCK5,CNTNAP2,DHRS3,FBLN1,MYO5C,TNS3,FRAS1,ICAM5,FCHO1,WNT3A,PLCB2,DPYSL5,WDR72,PLEKHA6,TESK1,SPATA13,KBTBD8,STRADB,SCRIB,PRX,MOSPD3,DHDH,MAPKAPK2,FA2H,COL13A1,CSF1,ITGA7,PRPS2,NLRC5,PLD1,ZDBF2,CDAN1,RNF146,USP43,NF2,DGKA,TP53,RHPN2,ERBB2,ZNF28,STIL,C1orf116,PDGFA,SRPX,WDR44,TACC2,PLCG2,PLK4,GYS1,NOTCH3,OAS3,FAR1,DVL2,CTH,CLCN3,AKT1,PTGER4,DAG1,PTGS2,DUOX1,TAPBP,IDE,PRRT4,C19orf66,ADAMTS14,ARHGAP4,NDST3,ZC3HC1,ZMAT1,CMAS,PACSIN2,GOLIM4,CPEB4,TAB3,MCTP2,HAL,ERCC6L,SLC9A2,NRP2,SIRPA,FZD6,DNAJB9,FOXP2,MAGEE1,FAM63A,IL17RA,SGK1,TSPAN13,ABCD1,ALDH7A1,SLC45A3,CAMK2G,TLE6,ATP2B1,MLEC,PLAUR,LITAF,MAML2,COL7A1,AKAP3,FXR2,CD83,USP6,FAT4,SCG2,NEIL3,NIPSNAP3A,CDCA7L,TMC5,FAM117A,ICOSLG,NDFIP1,UBE2C,HIPK3,ARHGEF9,ARHGEF4,GOLGB1,DIS3L,FAM171B,GAA,ACVR1,PPP4R4,HSPG2,SSH1,VANGL1,FAM129B,ATP8A1,PPFIBP2,C1orf198,PDGFRL,VASH1,CYP1A1,ANKS6,CTGF,OSBPL3,PRICKLE3,IL31RA,PIK3CA,KCNS3,AOX1,RCAN3,LAMP2,ORAI2,KIFC2,ACVR1C,CDYL,MGAM,KIF13A,CCNF,POR,SPNS3,RAB2B,ARHGEF26,AHRR,RBM47,BMP1,DHTKD1,SERPINI1,NFKBIZ,UNC5B,DDX58,SEMA6B,INPPL1,DHPS,TBC1D1,AKAP17A,NOTCH2,MESDC2,MECOM,DOPEY2,ITGA3,PIK3AP1,SLC16A6,AIM1,MSH2,PRKG1,SORL1,C8orf58,PIKFYVE,CTSD,KCTD3,GPR161,RIMS2,DNAI1,PIGC,DDB2,KCNJ12,QSOX1,FADS2,B3GNT7,KLK5,PRSS23,TBC1D8B,MICB,AMER1,DCHS1,PTPRH,PIP4K2C,PYGL,NPC2,ATP8B3,PKM,RASA1,STX3,FRMD4B,DGKH,AP1AR,NT5C2,SLCO4A1,PLEKHH2,TJP3,ISM1,DCK,SLC4A3,AGBL5,ARAP1,FAM83D,MPP2,FGD6,NR4A2,CABIN1,ZBTB34,PER3,IFIH1,PKD1L2,PLA2G4A,PLEKHG3,SLC2A4,CAPN12,CEP70,TRIP10,ST14,IQGAP1,RALBP1,CERCAM,ATP2C2,FAM78A,TMEM19,SNN,FLT3,AIFM2,ZFYVE9,CD46,ZNF75D,TRANK1,FICD,TNPO2,CNNM4,RNASEH2A,OSBPL7,PHKA2,NR2C1,MYO5B,DOCK4,COG2,TMEM43,FOXJ2,TEP1,UTRN,TMEM144,COX11,PRKCQ,SLC11A2,PYGO1,C15orf39,CBL,ITPR3,FZD7,AMZ2,DDOST,CCDC149,KIAA1804,STAT1,ZC3H12B,NR3C2,COBL,ATMIN,PLSCR4,SLC41A1,CENPI,NES,PLD2,DNAH3,PNPLA5,HLA-A,E2F7,FAM111A,RNF128,PTEN,MGAT1,ATP8B1,ERBB3,GFI1,TRIM62,OSGIN1,MSH6,NCOA2,PCCB,PDGFC,RASGRF1,ZWINT,ARAP2,PARP4,DIAPH2,FBXO9,ACADSB,FGFR2,TBX18,RIN3,AMMECR1,ABCB1,SERPINB5,PGM2L1,GRIN2D,ETAA1,FZD5,WDR62,CPEB2,ESPL1,MELK,OCLN,DEF6,JARID2,EXPH5,LTBP1,UGT8,TMEM184B,KIF2C,COMMD5,TMC1,CHPF,ABCD4,ARHGEF10L,SIPA1L2,HSF2,POF1B,ASH2L,MYH14,SLC39A10,MYRIP,RASGRP1,OLFML2A,TDP1,ASXL1,RGAG1,ARHGDIB,MRPS18A,MAN2A2,CXXC4,NEIL1,HPSE,FASTKD1,MADD,PSMC1,MIIP,CAPN1,PCSK5,SERPINE2,PPP1R12A,PEX6,PYROXD2,NOXA1,CES2,PFKL,OCRL,KCNN4,COL6A1,MTMR10,FNIP1,HLA-C,KNTC1,NCEH1,ZRANB1,LRIF1,ALS2CL,CCDC88A,KDELR1,PODXL2,PARD3B,OXR1,BTN3A2,VWA1,KIAA1109,HEATR5A,PRRC1,C3orf58,EGFR,MUM1L1,SOX13,GNAS,TSC1,ONECUT1,INSR,TMEM30A,RAB31,AFAP1,DRD1,KLF7,PROM2,LMO7,NCKAP5,PAX6,PDIA5,TDRKH,SLC25A48,SS18,ZNF687,KHNYN,FRYL,SMO,NFKB2,F2R,HSPA2,UPF3A,FRS3,SUSD3,GCA,MRPS35,DOCK5,FANCE,BFSP1,STAT6,TLE1,PLXND1,AKNA,SGOL1,MAD2L1BP,ABCA1,PPP2R2D,GLIS3,ARHGEF11,SHPRH,SH3D19,LRP4,TGFBR1,COL4A5,INTS8,SBF1,FAM167A,ITGA2B,TMEM63A,IRF2BPL,LLGL2,A4GALT,BMP7,ZDHHC13,KIAA0319,BRD7,TRIM3,ARVCF,RBMS2,MYO5A,ASPM,MBNL3,TTC7A,LEPR,MPV17L2,MAP1B,CD8A,PRCP,DTX4,GRAMD1C,HOXB13,AHR,L1CAM,NGEF,ZNF596,CD33 |
| 2.056e-04 | -8.49 | PDZ | interpro domains | IPR001478 | 151 | 39 | 18293 | 2672 |
LMO7,FRMPD3,USH1C,ARHGEF11,RHPN2,MPP5,APBA1,SLC9A3R2,PICK1,SNTA1,SIPA1L2,RGS12,RGS3,DLG1,TAX1BP3,DLG3,TIAM1,MAST4,DVL2,RIMS2,CASK,SNTB2,MPP1,RAPGEF2,PARD3B,SCRIB,ERBB2IP,SNTB1,RHPN1,PRX,PDLIM3,TJP3,GRID2IP,SHROOM3,LIMK1,SIPA1L1,MPP2,SHROOM2,APBA2 |
| 2.063e-04 | -8.49 | regulation of epithelial cell proliferation | biological process | GO:0050678 | 278 | 64 | 16441 | 2455 |
GATA3,ERBB2,OSR2,EGR3,VASH1,PDGFB,CCND1,TGFBR3,CTNNB1,DLG1,SMO,CDH3,CDKN1B,DAB2IP,TWIST1,TACSTD2,EPB41L4B,ETV4,SIRT1,AKT1,EAF2,SAV1,FZD7,TBX1,PEX2,NOD2,STAT1,ARNT,GRN,SCN5A,NKX3-1,CDKN1C,SOX9,TGFBR1,NRP2,SIX4,BMP2,CD109,RB1,PDCD10,PTEN,GPC3,BAX,KLF9,MYDGF,IQGAP3,CASK,WNT10B,NR4A1,RGCC,RUNX3,NFIB,EGFR,ACVRL1,SCG2,FGFR2,FGF18,TBX18,CTSV,NR4A3,SERPINB5,EGFL7,OSR1,XDH |
| 2.063e-04 | -8.49 | TRAF6 (TNF receptor-associated factor 6, E3 ubiquitin protein ligase) | protein interactions | 7189 | 252 | 62 | 16036 | 2547 |
SIGIRR,PINK1,NLRX1,TAB3,TRAF2,XIAP,PSMD7,TGFBR1,TNFRSF19,IL17RB,PSMD1,IRAK1,PSMC2,PPP4R1,CTPS1,IL17RA,WWP1,USP1,MAP3K7,LGMN,ZRANB1,TRAM1,SYK,MAP3K3,MBP,RIPK2,AKT1,ITCH,PLEKHO1,FHL2,STRADB,YES1,PELI3,IFIT3,CD40,CBL,ZFAND5,RANBP9,CASP4,VCP,BCL10,SOCS3,IL1R1,FYN,NGFRAP1,HTT,UEVLD,PELI2,PSMD3,CSNK1G1,TRAF3IP1,UBE2D2,MAP3K11,NOD2,ARRB1,OTUB2,IRF7,MAP3K5,TRAF5,PSMC1,RUSC1,NR2C2 |
| 2.064e-04 | -8.49 | insulin receptor signaling pathway | biological process | GO:0008286 | 305 | 69 | 16441 | 2455 |
SPRED1,SORBS1,PSME2,SLC2A8,ERBB2,NRG2,RASGRP3,PSME1,PDGFB,SPTB,PDGFA,CALM2,ATP6V0B,PSMD1,SHC3,PSMC2,PIK3CA,DAB2IP,RASGEF1A,RASGRP1,FRS3,AKT1,RHEB,IRS2,IDE,FYN,JAK1,PSMD3,CAB39,EIF4EBP2,SPTBN5,NRG1,GAB1,PSMC1,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,ATP6V1E2,PSMD10,CALM3,FGF19,DUSP5,IGF1R,ERBB3,NCAM1,PSMA5,CAMK2G,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,STRADB,BCAR1,PSMA4,RASA1,EGFR,GPLD1,TSC1,INSR,PRKAG2,FGFR2,FGF18,GRIN2D,ATP6V1C1,JAK3 |
| 2.070e-04 | -8.48 | cellular carbohydrate metabolic process | biological process | GO:0044262 | 148 | 39 | 16441 | 2455 |
GALK1,GAA,PPP1R2,UGP2,GNE,CALM3,NANS,ISYNA1,EXT2,EPM2A,PER2,CALM2,INPP5E,PTEN,IL6ST,IMPAD1,AKR1B1,GYS1,GOT1,PPP1CA,PHKA2,PHKG2,PGM1,B3GNT2,AKT1,PFKFB2,CALM1,MGAM,PYGL,IDH1,PRKAG2,GNPTAB,DGAT2,CSGALNACT1,PPP1CB,PGM2L1,GLB1,B4GAT1,ITPKA |
| 2.071e-04 | -8.48 | columnar_cell_lesion | COSMIC cancer mutations | columnar_cell_lesion | 35 | 14 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR |
| 2.071e-04 | -8.48 | breast-hyperplasia-columnar_cell_lesion | COSMIC cancer mutations | breast-hyperplasia-columnar_cell_lesion | 35 | 14 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR |
| 2.071e-04 | -8.48 | papilloma | COSMIC cancer mutations | papilloma | 35 | 14 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,SMO,PIK3CA,TP53,ERBB2,IDH1,GNA11,EGFR |
| 2.071e-04 | -8.48 | regulation of cell cycle G1/S phase transition | biological process | GO:1902806 | 153 | 40 | 16441 | 2455 |
PSME2,CUL4B,CTDSPL,PSMD7,TP53,PSMD10,PSME1,TP73,SUSD2,CCND1,E2F7,RB1,CYP1A1,PSMD1,PTEN,DACT1,KIF14,PSMC2,FBXO7,BRD7,CDKN1B,KANK2,PIM1,CTDSP2,PSMA5,ADAM17,AKT1,PSMB4,RGCC,PSMA4,EGFR,JADE1,TJP3,PSMD3,FAM83D,E2F1,PKD2,FHL1,PSMC1,CTDSP1 |
| 2.076e-04 | -8.48 | ZHAN_MULTIPLE_MYELOMA_CD1_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_DN | 43 | 16 | 17758 | 2588 |
HES1,UNC93B1,RAB3B,CXXC5,CPEB4,KIAA0040,F11R,BCL2L1,RAB3IP,ITPR3,CD46,TRAM2,TNS3,BHLHE41,FUT8,CMTM4 |
| 2.076e-04 | -8.48 | AMIT_EGF_RESPONSE_60_HELA | MSigDB lists | AMIT_EGF_RESPONSE_60_HELA | 43 | 16 | 17758 | 2588 |
HES1,PLSCR1,SOD2,RUNX3,NCKAP1,SLC20A1,RHOB,ATG4A,CCND1,CTGF,CYR61,FOSB,NR4A3,NR4A2,CITED2,TIPARP |
| 2.076e-04 | -8.48 | NAKAMURA_CANCER_MICROENVIRONMENT_DN | MSigDB lists | NAKAMURA_CANCER_MICROENVIRONMENT_DN | 43 | 16 | 17758 | 2588 |
RIPK2,AGPS,CDC20,CDCA2,KIF2C,DHRS3,FANCI,TNS3,ARTN,SHROOM3,IMPAD1,FAM83D,AURKA,BUB1,CCNB2,CTH |
| 2.080e-04 | -8.48 | carbohydrate derivative metabolic process | biological process | GO:1901135 | 1075 | 202 | 16441 | 2455 |
SLC35D2,ACACB,UGT8,AGRN,HSPG2,GNPDA1,SLC25A13,HEXB,FBXO2,NANS,MGAT5B,PLA2G16,CACNB4,SDC1,PIGL,CHST2,CHPF,TYMP,ENTPD4,MUC4,IMPAD1,PAPSS1,SERINC2,FUT1,DLG1,AKR1B1,TFG,TIPARP,MGAT5,APOBEC3G,TNIP1,CDA,ERP44,GALNT7,SLC17A5,ICMT,MCFD2,ARF4,VCP,MAN2A2,HS6ST1,ENPP1,NEIL1,HPSE,AREG,DOLPP1,GNPTAB,DHTKD1,GLA,POMT1,PPP2R5D,HS6ST3,ASAH1,NDUFA4,B4GALT4,ADAMTSL4,PGAP1,B4GALNT1,BMP2,GNS,CALR,B3GALNT1,PFKL,ATP5H,CTPS1,MSH2,AHCY,STT3B,PIM1,PPP6R1,MCCC2,TMED2,TRAK2,PIGC,CHSY3,NAGPA,GFPT1,PMPCB,B3GNT7,PQLC3,MGAT4B,GYLTL1B,PDE5A,CALCRL,PYGL,PKM,PDE11A,GLCE,GNAS,NUDT16,NT5C2,PRKAG2,UAP1,DCK,PRPS2,MPP2,CTSA,B4GAT1,ALG2,PLA2G4A,SLC2A4,UGP2,PAPSS2,IL15,GALNT12,XYLT1,PHLDA1,ART5,EXT2,MUC16,XYLT2,RPN2,PDE4D,APIP,LMAN1,DLG3,SULT2B1,NAGA,GM2A,CHP1,SULF2,SIRT1,ENPP4,SEC23A,AKT1,RFK,FIGNL1,PFKFB2,PANK1,PXYLP1,ATP1B1,B3GALNT2,ALDH5A1,DDOST,ABHD12,CANT1,SLC27A1,HS3ST3B1,B4GALT3,ST3GAL1,POMGNT2,NDST3,KDELC2,CMAS,TRAPPC10,ENO2,MAN1A2,SDC4,GNE,PDIA3,CTSZ,APOBEC3H,FBXO6,DSE,POMGNT1,FUT2,ITGB8,CTSC,ARSG,MGAT1,A4GALT,MGAT4A,ALG13,GPC3,GALNS,FUT8,UBE2J1,BAX,AK3,SLC35A1,GCNT1,HMMR,B3GALT6,PGM1,MLEC,B3GNT2,SHMT1,CASK,PLSCR1,GUSB,MPP1,PLAUR,PARP4,OGDHL,AK4,C1GALT1C1,COL7A1,ARSK,CPTP,FOXL1,GPLD1,GALNT3,FUCA1,SERPINA1,CTNS,SLC35B3,CSGALNACT1,GLB1,CMPK2,ARSB,ACOT7,OCLN |
| 2.084e-04 | -8.48 | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | MSigDB lists | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | 69 | 22 | 17758 | 2588 |
MMD,MPP1,RNF11,ASAH1,EIF2AK1,PRKAR2B,SNN,ITGA2B,GNAS,ENDOD1,MFAP3L,NGFRAP1,MYLK,PGRMC1,RAB31,TAX1BP3,CTSA,GLA,CTTN,FHL1,NRGN,TUBA4A |
| 2.085e-04 | -8.48 | RNGTGGGC_UNKNOWN | MSigDB lists | RNGTGGGC_UNKNOWN | 730 | 141 | 17758 | 2588 |
EMX1,ST13,EPAS1,CAMKK1,UBE2Z,NRG2,KIF2C,SEPT4,PDGFB,LTBP3,SH3KBP1,CALM2,CDKL5,DPYSL2,PACSIN1,PTPRE,SMYD5,BTBD3,ATL1,KCNIP3,CELSR2,RGAG1,TMEM151A,KLK6,IDH1,PGF,MAN2A2,KLF12,SH3GLB2,SPRY4,NRGN,GGA1,CALM3,APBA1,FRY,RALGPS2,LRRN2,MEGF8,FLRT3,FAM13B,RANBP1,RUNDC3B,SORL1,NCAM1,C9orf72,CKAP4,CCDC88A,KDELR1,SOCS5,B3GNT7,CALM1,SRSF5,PRRC1,ELK1,NFIB,PRX,GNAS,MOSPD3,NAB2,PRPS2,C1orf21,MPP2,LTBP2,RARG,RPS6KA3,KLF7,PROM2,DMPK,DRD1,KIF3C,HOXB7,RHBDL3,EGR3,BAHD1,SAP130,CCND1,KCTD15,ST5,WDR44,FABP6,VAT1,TNPO2,ACSL4,DLG3,DVL2,SEMA3B,CAPN6,PANK1,KIF1C,SP4,FYN,PAFAH1B3,CORO1C,STAT6,OVOL1,ADAMTS14,EFNA5,KLF5,NRG1,RGS14,RPL22,AIFM3,PRR15,COBL,OTUD5,COL9A3,ANKRD13D,PCOLCE,PDIA3,HMGN3,EFNB1,SIX4,WWP2,ADD3,ITGB8,PPP1R10,GPC3,CALD1,RRBP1,AK3,HEXIM2,CITED2,GFI1,SUN2,ADAMTS2,NUDT8,LONRF3,NR3C1,NR4A1,BCL9,VAMP3,PITX2,BTG1,NUCB1,SYT7,NR4A3,E2F1,CCDC69,FZD5,CEP41,FOXA1 |
| 2.087e-04 | -8.47 | REACTOME_HEMOSTASIS | MSigDB lists | REACTOME_HEMOSTASIS | 448 | 93 | 17758 | 2588 |
PLA2G4A,KIF3C,KLC2,DGKA,TP53,GATA3,F11R,KIF2C,ITPR2,PDGFB,PRKACA,KIF26A,GNB2,CALM2,PDGFA,WEE1,STIM1,PLCG2,PIK3CA,IRF2,KIF22,F2R,RASGRP1,TUBA4A,LAMP2,DOCK4,SOD1,AKT1,PRKCQ,PRKAR2B,F12,ATP1B1,ITPR3,DOCK5,PLCG1,FYN,KCNMB4,PPP2R5A,HDAC1,IRF7,PPP2R5D,MAFF,PRKAR1A,CD63,DGKQ,HABP4,KIF23,SELL,CALM3,RACGAP1,MERTK,SIRPA,ITGA2B,KIF5B,RAC2,ITGA3,TIMP1,GNB5,GATA2,KLC3,PRKG1,CD9,AK3,DGKG,SYK,RHOA,KIF20A,PLAUR,CALM1,PIK3R1,HMG20B,PDE5A,YES1,BCAR1,KIF11,GNA11,DGKE,RHOB,PDE11A,RASGRP2,GNAS,DGKH,SERPINA1,PRCP,ARRB1,ITGAV,ATP1B3,CBX5,TRPC3,L1CAM,IRF1,EHD1,DOCK9 |
| 2.100e-04 | -8.47 | V$TFIIA_Q6 | MSigDB lists | V$TFIIA_Q6 | 241 | 56 | 17758 | 2588 |
ANXA3,INPPL1,PAX6,TMEM184B,HAPLN3,TSC22D3,KLC2,ABCG4,NKRF,CDIPT,VASH1,KTN1,LMNA,CCND1,SAP130,TFAP4,FOXP2,VASP,ADD3,ITGA3,ANKS1B,GPC3,LHX6,FOSB,BCL6,CDH3,RFX5,ETHE1,ARMCX6,BTBD3,STK35,CKAP4,FRS3,SSH3,MAPKAPK3,NR4A1,ITCH,FHL2,CBX6,HMG20B,EPHA1,PDIK1L,NFIB,NIN,MMP15,TSC1,STX10,HOXA9,AXL,PELI2,MPP2,KLK7,REEP4,COL16A1,ABCA1,GOLGB1 |
| 2.107e-04 | -8.47 | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDM_DN | 193 | 47 | 17758 | 2588 |
TBC1D1,FRMD6,RUSC2,OSGIN2,NDRG2,F11R,CCNL1,BCL2L1,PLA2G16,RAD23A,ATP6V0B,RPS6KA2,ADRBK1,ARTN,PIK3AP1,MITF,IL17RA,CTTN,SGCB,MGAT5,TSPAN33,TESK1,SYNE2,DIAPH2,CCBL2,IGSF8,PRRC1,CYFIP2,MAP3K6,ABR,ARF4,CD83,MAPKAPK2,PLCG1,PTPRJ,PPP2R5A,RND3,SEC14L4,NFKBIA,ZDHHC20,TDRD7,HDAC1,AKNA,TTC39C,TRAF5,JARID2,PCSK5 |
| 2.107e-04 | -8.47 | V$HFH8_01 | MSigDB lists | V$HFH8_01 | 193 | 47 | 17758 | 2588 |
LASP1,FRMD4A,CPEB4,HOXB7,ETV5,ARFGEF1,KCTD12,HMGN3,TSPAN17,BEX2,CCND1,FOXP2,TFAP4,KCTD15,ARTN,NECAB3,SLC16A6,FLRT3,LMO4,KLF3,DUSP1,CYP26B1,SSH3,TGIF1,CXXC5,ASXL1,NR4A1,SLC39A8,FHL2,CBX6,RGAG1,YES1,NFIB,NIN,KLF12,PDLIM3,COL13A1,PELI2,PPP1CB,NR4A2,PRIMA1,REEP4,CDAN1,STARD13,TOB1,ABCA1,RAD21 |
| 2.107e-04 | -8.47 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | 193 | 47 | 17758 | 2588 |
MYL9,CD99,UGP2,ALDH6A1,MRPS15,HEBP1,CAST,ASL,MCCC1,PBX3,NDRG2,P2RX7,PSME1,NENF,DPP8,REPS1,HMGXB4,ITGA2B,COX7A2,ARHGEF10L,PDGFA,FAM46A,DLG1,CTTN,NCAM1,NCOA2,MMD,LAP3,TEP1,CCBL2,HTATIP2,PRKAR2B,KIF11,SLC25A5,SFXN1,ENDOD1,MFAP3L,SERTAD2,DNM1L,PTER,MYLK,UBE2D2,PGRMC1,TMEM8B,FHL1,NRGN,ATMIN |
| 2.112e-04 | -8.46 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | 97 | 28 | 17758 | 2588 |
GAS2L1,LASP1,DCAF6,ZWINT,NQO1,GCAT,DSTN,EPS8,RGS20,RACGAP1,ARHGDIB,HMGN3,GALNT7,ISOC2,ALCAM,FBLN1,ATP10D,PLS3,TNS3,DPYSL2,CALD1,AIM1,KANK2,ATP1B3,ZMIZ1,SPRY2,TOB1,RUSC1 |
| 2.113e-04 | -8.46 | regulation of cell-cell adhesion | biological process | GO:0022407 | 371 | 81 | 16441 | 2455 |
CASP3,NF2,IL15,GATA3,ERBB2,IL18,EGR3,CD274,TNFSF9,EPCAM,CD46,CDH1,CTNNB1,IL6ST,BCL6,PIK3CA,DLG1,FLOT2,RASGRP1,SOD1,CD55,CELSR2,RIPK2,AKT1,LGALS8,ITCH,DMTN,PRKCQ,FYN,NOD2,EFNA5,PIEZO1,RAP1GAP,PRKAR1A,LGALS3,SERPINE2,DHPS,TRAF2,UBASH3B,HLA-E,ITGA6,FLOT1,EFNB1,HLA-A,BMP2,RAC2,BMP7,PAK2,PRKG1,FXYD5,IGFBP2,C10orf54,WNT3A,MAPK7,RAG1,MAP3K7,CITED2,SYK,SOCS5,EPB41L5,HES1,RHOA,PIK3R1,RGCC,PPARA,PDE5A,YES1,SOX13,CD83,BCL10,SWAP70,PLPP3,SPINT2,TBX18,NR4A3,ICOSLG,NDFIP1,JAK3,L1CAM,FOXA1,IRF1 |
| 2.118e-04 | -8.46 | VALK_AML_CLUSTER_11 | MSigDB lists | VALK_AML_CLUSTER_11 | 35 | 14 | 17758 | 2588 |
GAS2L1,FYN,ALDH2,H1F0,KCNN4,DPYSL2,ITGA6,SERPINB9,DAPK1,EGFL7,MDFIC,KLF9,LHFPL2,MYO5C |
| 2.128e-04 | -8.46 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | MSigDB lists | PID_ECADHERIN_NASCENT_AJ_PATHWAY | 39 | 15 | 17758 | 2588 |
CCND1,RHOA,AKT1,CTNNB1,CDH1,IQGAP1,PIK3R1,DLG1,PIK3CA,CTNND1,CTTN,NCKAP1,CYFIP2,ARF6,TIAM1 |
| 2.128e-04 | -8.46 | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_H2O2 | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_H2O2 | 39 | 15 | 17758 | 2588 |
FECH,CTNNB1,ITGA7,CDC20,MYBL2,NFE2L1,UBE2A,ERBB2,SYP,IL18,ELK1,F2R,CDKN2D,SPRY2,GNB2 |
| 2.134e-04 | -8.45 | Kinesin-like_fam | interpro domains | IPR027640 | 43 | 16 | 18293 | 2672 |
KIF3C,KIFC2,KIF20A,KIF1C,KIF23,KIF20B,KIF13A,KIF2C,KIF11,KIF26A,KIF5B,KIF13B,KIF14,KIF22,CENPE,KIF12 |
| 2.166e-04 | -8.44 | regulation of cytokinesis | biological process | GO:0032465 | 95 | 28 | 16441 | 2455 |
CCNC,ADAM17,PSRC1,RHOA,AKT1,CIT,CALM1,RGCC,CALM3,KIF23,PSMD10,RACGAP1,KIF20B,AURKB,CCNL1,PDGFB,STIL,EGFR,CALM2,CCND1,E2F7,IGF1R,KIF14,AURKA,PKD2,PIM1,E2F8,HSPA2 |
| 2.171e-04 | -8.44 | REACTOME_CELL_CYCLE | MSigDB lists | REACTOME_CELL_CYCLE | 397 | 84 | 17758 | 2588 |
CCNE2,SPC25,CEP70,TUBB4B,PSME2,PTTG1,NDC80,TP53,CUL1,NUF2,PSME1,KIF2C,CCNB1,PRKACA,CENPN,CCND1,CDKN2C,WEE1,PCNA,PSMD1,CCNA2,CNTRL,PSMC2,PLK4,CDKN1B,TUBG1,CDKN2D,HSPA2,TUBA4A,PLK1,CENPA,CDC20,SYNE2,PRKAR2B,AURKB,PKMYT1,RAD17,CDC25C,CDK1,GINS4,PRIM1,PPP2R5A,RBL1,PSMD3,HDAC1,SGOL1,PPP2R5D,PSMC1,HJURP,CENPI,PSMD7,CDCA8,ERCC6L,KIF23,PSMD10,LMNA,CKAP5,RB1,CENPJ,TUBGCP6,NEK2,CKS1B,BUB1,KNTC1,NUP85,PSMA5,REC8,SUN2,ZWINT,KIF20A,PSMB4,B9D2,MYBL2,POLD3,SKA1,PSMA4,E2F1,AURKA,SSNA1,CEP41,NUP37,CCNB2,UBE2C,RAD21 |
| 2.178e-04 | -8.43 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 188 | 46 | 17758 | 2588 |
KLF2,ST13,CD63,TSC22D3,HABP4,PSME1,C3orf18,HOXB2,ECI1,EPS8L2,ADORA1,ATP5H,KLF3,AIM1,PASK,SORL1,PIM1,SMAGP,CKAP4,DUSP1,MARK1,ADCK3,STAT4,S100A4,CXorf57,CBX6,RNF113A,NPC2,PYGO1,ALCAM,FUCA1,ENDOD1,GABRD,LDLRAP1,SERPINA1,WFS1,LRIG1,FAM117A,PDXK,MAP3K5,TBC1D4,LTA4H,NR3C2,APOL2,SNPH,DOCK9 |
| 2.178e-04 | -8.43 | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP | MSigDB lists | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP | 188 | 46 | 17758 | 2588 |
GAS2L1,NKX3-1,ZNF395,OSGIN2,TDRKH,MGST2,DSE,OAT,FZD6,LMNA,ZFP36,N4BP3,FAM102A,LGMN,ITM2C,EEF1D,CPD,NAGPA,SYPL1,PLEKHA6,ELK3,ADCK3,SLC39A8,PTGER4,PLS1,KIF13A,RUNX3,ASB13,SESN1,LEPR,RASA1,GABARAPL1,PLCH1,BTG1,NEIL1,AREG,PLK2,MATN2,ABCB1,PRKCDBP,ADIPOR1,PPP2R3C,APBA2,MAFF,TOB1,PKIA |
| 2.178e-04 | -8.43 | GSE17721_CTRL_VS_LPS_1H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_1H_BMDM_DN | 188 | 46 | 17758 | 2588 |
MRC2,USH1C,FLYWCH2,CCNL1,FAM81A,CYP26A1,ICAM1,DNAJB9,IER3,BTG3,CYR61,LLGL2,ZFP36,BHLHE41,RDH14,MTMR10,TPST1,CITED2,RAG1,TIPARP,C9orf72,FBLN5,B3GNT2,RIPK2,PLSCR1,WNT10B,NRBF2,NR4A1,SH3BGRL,PTGER4,CR2,KIF13A,ASB13,FOS,COL12A1,EDNRA,TXK,IRS2,PGF,FAM64A,RND3,NKD1,OSR1,MAFF,PROM2,EHD1 |
| 2.178e-04 | -8.43 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 188 | 46 | 17758 | 2588 |
BIN1,SCN5A,KLF2,ST13,HLA-E,ITGA6,HABP4,ASAH1,NENF,B4GALT4,C3orf18,DENND2D,TIMP1,IL6ST,COL6A1,FAM63A,SORL1,WWP1,CRY2,PIK3CD,PIM1,PLCB2,ALDH3A2,TMBIM1,EEF1D,CD55,TNIP1,UXT,FOXJ2,MGAT4B,LITAF,STX3,ULK2,TCN2,FUCA1,BTG1,SCARB2,RPL12,DGCR2,INPP4B,DTX4,PDXK,TBC1D4,NR3C2,APOL2,EHD1 |
| 2.182e-04 | -8.43 | ENDOPLASMIC_RETICULUM | MSigDB lists | ENDOPLASMIC_RETICULUM | 285 | 64 | 17758 | 2588 |
PDIA5,DNAJB11,ITPR2,ERP29,KTN1,EXT2,RCN1,P4HB,STIM1,LMAN2L,RDH14,RPN2,MINPP1,LMAN1,PDIA6,TRAM1,ERAP2,SEMA3B,SOAT1,SEC23A,SEC61B,TMEM98,ACO1,BNIP3L,KIF1C,ERP44,PKMYT1,ICMT,TMTC2,ITPR3,POR,VCP,TAPBP,AGPAT2,DDOST,DNM1L,DOLPP1,SLC9A6,POMT1,AIFM3,HSP90B1,PDIA3,CTSZ,DSE,PGAP1,DNAJB9,PDIA4,CALR,CES2,ARSG,NECAB3,BAX,TMBIM6,STT3B,CCDC88A,TMX1,PIGC,AMFR,TMEM50B,CASP7,PLOD2,ERAP1,CTSA,PLOD3 |
| 2.184e-04 | -8.43 | PTB/PI_dom | interpro domains | IPR006020 | 39 | 15 | 18293 | 2672 |
TNS3,LDLRAP1,RGS12,TBC1D1,SHC3,ANKS1B,EPS8,CCM2,APPL2,TNS1,APBA1,APBA2,TBC1D4,EPS8L2,MAPK8IP1 |
| 2.188e-04 | -8.43 | MEMBRANE_FRACTION | MSigDB lists | MEMBRANE_FRACTION | 335 | 73 | 17758 | 2588 |
LAMP1,IL15,SLC7A2,MGST2,KREMEN1,KTN1,CYP39A1,SYTL2,STEAP2,FUT1,ECE1,OAS3,PXMP4,RASGRP1,LAMP2,CPD,PPIF,MCTP1,SNTB2,UTRN,ARFRP1,SLC17A5,PKMYT1,ICMT,DAG1,VCP,ATP1A1,SLC9A6,WFS1,ARF6,RAP1GAP,ABCA1,GALK1,HSP90B1,TSPAN15,MAN1A2,MCTP2,STRN4,SLC1A3,POMGNT1,NRP2,B4GALNT1,A4GALT,SLC16A6,TPST1,ATP8B1,TSPAN13,CD70,HSPA13,SLC12A2,SLC16A5,CKAP4,TMX1,TMED2,KDELR1,ABCC1,FADS2,MMD,MPP1,AMFR,RC3H2,CYFIP2,BCAR1,GALNT3,HLA-B,SCARB2,FAAH,ABCB1,MPP2,DGAT2,SLC4A3,ARRB1,PTGES |
| 2.188e-04 | -8.43 | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | MSigDB lists | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | 83 | 25 | 17758 | 2588 |
MBP,MRC2,PINK1,CDKN1C,PLAUR,PYGL,PLXNA1,SNN,PDGFB,PHLDA1,DDR1,PHF1,GNA11,LMNA,RHPN1,PRX,PICK1,SNTA1,NOXA1,MITF,RAB11FIP1,TRIOBP,PIK3CD,EPHB4,DUSP1 |
| 2.188e-04 | -8.43 | V$EGR3_01 | MSigDB lists | V$EGR3_01 | 83 | 25 | 17758 | 2588 |
SIRT1,SUN2,CMAS,SCN5A,MRC2,PCOLCE,KREMEN2,UBASH3B,HMG20B,TP53I11,EGR3,PRKACA,PDGFB,HDAC9,MAN2A2,CDKN2C,RALGPS2,ITGB8,WDR44,RANBP1,KLF5,ATP6V1C1,SMYD5,ETV4,C9orf72 |
| 2.200e-04 | -8.42 | Prolonged ERK activation events | REACTOME pathways | R-HSA-169893 | 235 | 56 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,PLCG1,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 2.212e-04 | -8.42 | CTGCAGY_UNKNOWN | MSigDB lists | CTGCAGY_UNKNOWN | 713 | 138 | 17758 | 2588 |
DOC2A,ACVR1,ST13,GRIK2,PPM1J,TSC22D3,CAMK1D,SEPT4,PDGFB,CALM2,CDKL5,DPYSL2,SLC44A1,KCNS3,TUBA4A,OLFML2A,SH3BGRL,DSTN,PNKD,DPYSL3,PGF,KLF12,ZNF367,HOXA9,SH2D3C,NKD1,CTNND1,SPRY4,STARD13,NRGN,FRMD4A,NUAK1,ETV5,CALM3,NDUFA4,FAM81A,TSPAN7,MECOM,TFAP4,PRICKLE4,FLRT3,EXOC8,SORL1,TNFRSF12A,PIM1,MAPK7,C9orf9,ELK3,PLEKHA6,KIAA1841,ADCK3,CALM1,RHOB,MAGED2,EPN3,ITGA7,NFKBIA,NXPH4,RHOBTB2,RPS6KA3,RUSC1,CCNE2,SPRED1,KIF3C,PAX6,GMPR,EGR3,PRR7,FLT3,APC2,SYTL2,TACC2,SH3BP1,LMO4,GYS1,PDE4D,EPB41L4B,OSBPL7,DLG3,SCN2A,ETV4,FRS3,SLC5A11,BAG4,FZD4,ATP1B1,TMTC2,ALCAM,NFIX,AMZ2,FYN,NGFRAP1,C19orf66,SLC9A6,NRG1,PRIMA1,NR3C2,IER5L,GALK1,FARP1,ENO2,KLHL13,ARMC7,SIRPA,HDAC9,IRF2BPL,ZFX,ADD3,GPC3,TRIM3,TSPAN13,WWP1,HEXIM2,CITED2,CAMK2G,DLGAP1,ADAMTS2,TGIF1,CASK,RHOA,PIK3R1,CRIP2,DPP9,FBXO9,COL7A1,PELI3,FOS,MAP1B,SMTNL2,GRIN2D,FHL1,GEM,SHOX2,DEF6,JARID2,DIS3L,SNPH,ABCG1 |
| 2.222e-04 | -8.41 | YOSHIMURA_MAPK8_TARGETS_DN | MSigDB lists | YOSHIMURA_MAPK8_TARGETS_DN | 352 | 76 | 17758 | 2588 |
KIF3C,ACVR1,PAPSS2,RALBP1,CCNL1,CMTM6,APLP2,SRPX,IL6ST,PSMC2,DNM2,RPN2,CTTN,EGLN3,GM2A,CTH,SEC61B,TCEB2,AKT1,LGALS8,PFKFB2,BCL7B,PTGFRN,POR,PTPRJ,IDE,DDOST,MAP2,STK38,SIPA1L1,SLC27A1,NRG1,RPL22,GCLM,PACSIN2,MPZL1,IGFBP6,DCAF7,NCKAP1,LBR,DNAJB9,VPS26A,NEO1,TOP2A,TNS3,RB1,CST3,MSH2,EXOC8,TMBIM6,NPTN,ALDH3A2,CASK,MAPKAPK3,AMFR,FHL2,LITAF,KIF11,PTPRF,FUCA1,NUCB1,SLC6A6,TIMP3,SLC4A4,SCG2,HTT,NR1D2,DBI,ITPR1,PITPNA,NR4A2,STK39,LTBP2,KIF12,HOOK1,AHR |
| 2.224e-04 | -8.41 | cyclin-dependent protein serine/threonine kinase regulator activity | molecular function | GO:0016538 | 27 | 12 | 16491 | 2452 |
CCNE2,CCNC,CCND1,CDKN2C,CASP3,CDKN1C,CKS1B,CDKN1B,HEXIM2,CCNL1,CDKN2D,CKS2 |
| 2.225e-04 | -8.41 | CAIRO_HEPATOBLASTOMA_CLASSES_DN | MSigDB lists | CAIRO_HEPATOBLASTOMA_CLASSES_DN | 204 | 49 | 17758 | 2588 |
FAM189A2,PSME2,ZCCHC24,TSC22D3,COL18A1,BLCAP,CAMK1D,PHLDA1,HDAC9,SGPL1,CAPN2,CYP1A1,TRANK1,FRY,IL6ST,AOX1,DAPK1,ABCA2,BCL6,TFAP2A,KANK2,MTMR11,SGCB,MYRIP,MAST4,KANK3,ALDH3A2,SNED1,AMOTL2,RASGRF1,ALDH2,KIAA0040,LDB2,CASP4,FAS,GABARAPL1,IL1R1,MFAP3L,FAT4,SLC4A4,NR1D2,KCNK1,NFKBIA,MYLK,TTC9,MAP3K5,CD81,MYL12B,CSRP2 |
| 2.229e-04 | -8.41 | AATGTGA,MIR-23A,MIR-23B | MSigDB lists | AATGTGA,MIR-23A,MIR-23B | 403 | 85 | 17758 | 2588 |
LAMP1,PPP4R4,LGR4,XIAP,MPP5,BLCAP,EGR3,FANCI,MAGOHB,CCND1,PAK6,RCN1,TGFBR3,ELF5,KLF3,FOSB,IRF2,ANO4,PDIA6,STK35,MAP3K3,PPIF,SEC23A,CLCN3,CAPN6,PTGER4,BNIP3L,MCFD2,LHFPL2,IDH1,NIN,GPRC5B,LRIG1,KIAA1804,PPP1CB,CAB39,KLF5,ARF6,NRGN,ATMIN,RUNX2,CPEB4,PPP1R12A,ZNF395,TAB3,NUAK1,COL4A5,LBR,DUSP5,HMGXB4,SIRPA,CTNNBIP1,CA2,ADRBK1,FAM13B,FNIP1,SGK1,MDFIC,SPRY2,FAM134C,MDFI,CHSY3,TGIF1,DENND1B,CXorf57,WHSC1,C2orf69,BORA,CDK5R1,GLCE,FAS,CASP7,SLC4A4,RAB11FIP2,CCDC6,CSNK1G1,AMMECR1,OTUB2,PCDH19,PITPNA,AKIP1,MAP3K5,CPEB2,PKIA,IRF1 |
| 2.244e-04 | -8.40 | DANG_REGULATED_BY_MYC_DN | MSigDB lists | DANG_REGULATED_BY_MYC_DN | 247 | 57 | 17758 | 2588 |
LAMP1,CASP3,GAA,CAST,ARHGEF7,NDRG1,CTSB,GABRG2,ERBB2,FTH1,SEPT4,PDGFB,TSPAN7,PLS3,IER3,CCND1,RB1,CTGF,CALD1,KIF14,PAK2,CDKN1B,ARVCF,IFIT1,PIM1,NCAM1,F2R,IL1RAP,GM2A,DUSP1,LAMP2,CPD,DDB2,FADS2,TIMP2,FBLN5,AKT1,PLAUR,VAMP3,CKAP2L,NPC2,CYFIP2,ILK,MYL12A,TCN2,ARF4,FAS,GNAS,NUCB1,WFS1,PPP2R4,PRKCDBP,IRF7,PLD1,HSPB1,SERPINB1,KLF7 |
| 2.248e-04 | -8.40 | positive regulation of innate immune response | biological process | GO:0045089 | 295 | 67 | 16441 | 2455 |
LAMP1,UNC93B1,TRIM5,RPS6KA1,PSME2,CUL1,PSME1,ITPR2,PRKACA,CALM2,PSMD1,RPS6KA2,PSMC2,PLCG2,NFKB2,SCARA3,LGMN,RASGRP1,SMAGP,RIPK2,TNIP1,ITCH,ITPR3,DUSP4,FYN,PSMD3,NOD2,IRF7,PSMC1,PPP2R5D,DDX58,HSP90B1,TAB3,CTSB,HLA-E,PSMD7,PSMD10,CALM3,IRAK1,PIK3AP1,PAK2,MAPK11,MAPK7,MAP3K7,CNPY3,SYK,PSMA5,PSMB4,PLSCR1,MAPKAPK3,CALM1,ELK1,FOS,PSMA4,TXK,BCL10,CTSL,MAPKAPK2,PVRL2,PELI2,NFKBIA,ITPR1,UBE2D2,NLRC5,IFIH1,RPS6KA3,TMEM173 |
| 2.249e-04 | -8.40 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 183 | 45 | 17758 | 2588 |
CASP3,ADD1,MPZL1,TMX4,CCM2,MTL5,KCTD12,GMCL1,NTAN1,FAM101B,IRF2BPL,CD46,MARCH8,NOV,PCNA,ADD3,SNX18,METTL7A,ZNRF2,TAX1BP3,BRAT1,PPP1CA,FAR1,MYO5A,FAM134C,CERS2,ORAI2,PQLC3,TACC1,KIAA0040,LPGAT1,NUB1,VPS4B,STMN3,STK17B,VCP,ZMPSTE24,DGCR2,RAB11FIP1,CCDC69,HDAC1,LRRK1,MAP3K5,BTBD6,LRRC57 |
| 2.249e-04 | -8.40 | GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN | 183 | 45 | 17758 | 2588 |
PSME2,HEBP1,CNOT8,FAM134A,TAP1,XIAP,ERI2,TXNDC9,FBXO6,NTAN1,HERC6,SLC25A43,EXT2,BMP2K,CTSC,SGK3,HYLS1,FAR2,IL10RB,LAMP3,PARP9,PLSCR1,USP18,IFIT3,RHEB,BCL10,ZMPSTE24,TMEM50B,NT5C2,PI4K2B,SCARB2,ZNF641,CASP7,TRIM69,SETD3,NMI,SECTM1,STAT1,AURKA,PPP2R3C,CTNND1,CYP2U1,CMPK2,IFIH1,SLC31A2 |
| 2.251e-04 | -8.40 | LUCAS_HNF4A_TARGETS_UP | MSigDB lists | LUCAS_HNF4A_TARGETS_UP | 56 | 19 | 17758 | 2588 |
MTM1,LASP1,MPP1,SDC4,PKP2,IL13RA1,MGST2,SEPP1,IL18R1,ALDH5A1,TACC2,ATP7B,KIF13B,OSBPL3,ABCB1,ERBB3,TECR,COBL,SMAGP |
| 2.251e-04 | -8.40 | BORLAK_LIVER_CANCER_EGF_UP | MSigDB lists | BORLAK_LIVER_CANCER_EGF_UP | 56 | 19 | 17758 | 2588 |
TGIF1,PLSCR1,S100A11,CD63,CCNB1,FOS,ALCAM,DDR1,CDK1,ELF3,CCND1,PDGFA,BTG3,SPP1,CA2,ETS2,SERPINB6,CPE,WBP5 |
| 2.272e-04 | -8.39 | Downstream signaling events of B Cell Receptor (BCR) | REACTOME pathways | R-HSA-1168372 | 168 | 43 | 8202 | 1235 |
TNRC6C,NFKBIE,PSME2,PSMD7,PSMD10,ERBB2,NRG2,CUL1,RASGRP3,PSME1,PHLPP1,PDGFB,FGF19,PDGFA,PSMD1,PTEN,PSMC2,PIK3CA,CDKN1B,PIK3CD,ERBB3,MAP3K7,RASGRP1,PSMA5,AKT1,PSMB4,NR4A1,PIK3R1,CASP9,AGO4,PSMA4,EGFR,BCL10,IRS2,FYN,FGFR2,PHLPP2,PSMD3,NFKBIA,FGF18,NRG1,PSMC1,GAB1 |
| 2.278e-04 | -8.39 | FBXO6 (F-box protein 6) | protein interactions | 26270 | 618 | 131 | 16036 | 2547 |
SUN1,LAMP1,LTBP1,GAA,UGT8,FAF2,HSPG2,SLC25A13,HEXB,CUL1,DNAJB11,PLXNA1,OAT,LTBP3,CHPF,PCNA,NUP210,P4HB,PSMC2,DNM2,TUBG1,PLK1,EZR,PTGFRN,SLC25A5,CDK1,ARF4,VCP,MAN2A2,GLA,PSMC1,GRN,MRC2,PSMD7,ASAH1,ADAMTSL4,LMNA,KIAA1161,GNS,RAC2,ITGA3,IGF1R,TIMP1,PFKL,ICAM5,MEGF8,COL6A1,CTPS1,SORL1,AHCY,HLA-C,NPTN,STT3B,CTSD,NUP85,EEF1D,IGSF3,ERO1A,EMC2,PKM,ILK,PSMA4,EGFR,FECH,CACHD1,NAAA,APMAP,CTSA,B4GAT1,SERPINB1,SLC25A24,TCTN2,CERCAM,COL18A1,PCBP1,RPN2,ECE1,MINPP1,LGMN,PDIA6,NAGA,CPD,ERLEC1,IGSF8,B3GALNT2,PTPRJ,ATP1A1,DDOST,PSMD3,STK38,B4GALT3,POMGNT2,LIFR,KDELC2,MAN2B2,CMAS,GALK1,HSP90B1,GCAT,CTSB,EFHD2,CTSZ,ITGA2B,LGALS3BP,M6PR,CKAP5,ALPP,CTSC,TRIM21,ADAM15,HSPA13,CRTAP,SMC4,ADAM17,GUSB,TMEM245,GGH,KIF11,TXNDC11,LEPR,CNTNAP1,PLOD2,PRCP,HNRNPH2,PLA2G15,GLB1,SPCS3,ITGAV,PLOD3,L1CAM,TMEM131 |
| 2.293e-04 | -8.38 | BHAT_ESR1_TARGETS_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_VIA_AKT1_UP | 269 | 61 | 17758 | 2588 |
IER5L,FARP1,KLK10,ARAP3,PARP12,SLC2A8,RET,EFHD2,GDF15,SLC7A2,DHRS3,FAM46C,QSOX2,LTBP3,NCS1,CYP26A1,IER3,C16orf74,CCND1,SCNN1A,MLPH,CYP4F11,A4GALT,REEP1,FCHO1,TMEM51,FAM102A,CTSD,TIPARP,TIAM1,SULT2B1,OSGIN1,CYP1B1,SEMA3B,PPIF,SUSD3,CXXC5,CELSR2,SYBU,MYEOV,FHL2,ASB13,FOS,SEC14L2,ALDH3B1,TRIM47,SLC6A6,PRKAG2,SMTNL2,TJP3,PDLIM3,DHRS2,MFSD2A,WFS1,LRIG1,NOD2,FAM195A,XRCC3,GLA,AKNA,PTGES |
| 2.295e-04 | -8.38 | cellular response to decreased oxygen levels | biological process | GO:0036294 | 124 | 34 | 16441 | 2455 |
PINK1,NKX3-1,SLC2A4,CPEB4,EPAS1,NDRG1,PRKAA1,TP53,CCNB1,ICAM1,PICK1,LMNA,IRAK1,P4HB,PTEN,BMP7,VASN,TWIST1,CITED2,EGLN3,HP1BP3,SIRT1,AKT1,TCEB2,RGCC,SLC11A2,PDK3,PTGS2,UBE2D2,E2F1,CPEB2,ARNT,EGLN1,DRD1 |
| 2.295e-04 | -8.38 | embryonic epithelial tube formation | biological process | GO:0001838 | 124 | 34 | 16441 | 2455 |
CTHRC1,GRHL2,ST14,SOX9,SDC4,RET,RAB23,GATA3,NCKAP1,PRKACA,STIL,FZD6,VASP,CTNNB1,LMO4,TWIST1,MAP3K7,DVL2,TGIF1,SALL4,PRICKLE1,KIF20B,SCRIB,BCL10,ARHGAP35,IRX3,TSC1,SHROOM3,PTK7,SPINT2,SOX8,OSR1,COBL,RARG |
| 2.297e-04 | -8.38 | ERBB4 (erb-b2 receptor tyrosine kinase 4) | protein interactions | 2066 | 56 | 20 | 16036 | 2547 |
ADAM17,SNTB2,ITCH,TP53,NRG2,ERBB2,CBL,HDAC6,EGFR,RASA1,PIAS3,CTGF,ANKS1B,LRIG1,DLG1,WWP1,NRG1,ERBB3,DLG3,SYK |
| 2.298e-04 | -8.38 | V$CEBPA_01 | MSigDB lists | V$CEBPA_01 | 231 | 54 | 17758 | 2588 |
PLA2G4A,SPRED1,NCKAP5,HOXB7,THRA,FAM91A1,CA8,S100A2,PDGFB,NFAT5,NRP2,SIRPA,XPR1,SCML1,CALR,CD109,FOXP2,ANKS1B,CDKL5,LMO4,LHX6,MITF,RRBP1,BCL6,CLDN4,GYS1,PDE4D,SSH3,SMARCA2,CD55,MCTP1,CASK,TRIM8,WNT10B,LONRF3,MOSPD2,SERTAD4,RC3H2,CBX6,RAB3IP,PPP1R14C,SPTLC2,EGFR,LEMD2,COL13A1,PPP1CB,OSMR,MAOA,RHOBTB2,ARF6,TOB1,ARNT,CBX4,JARID2 |
| 2.298e-04 | -8.38 | NS-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | NS-carcinoma-squamous_cell_carcinoma | 17 | 9 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 2.298e-04 | -8.38 | anaplastic | COSMIC cancer mutations | anaplastic | 17 | 9 | 17775 | 2585 |
CDKN2C,NF2,CTNNB1,AKT1,PTEN,SMO,PIK3CA,IDH1,EGFR |
| 2.302e-04 | -8.38 | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_E_COLI_VS_STREP_AUREUS_INF_PBMC_UP | 147 | 38 | 17758 | 2588 |
KLF2,LZTFL1,CCDC109B,CDKN1C,TSC22D3,APOO,DHRS3,ETS1,CORO1B,ADD3,IL6ST,SRR,FAM102A,DIXDC1,NCOA2,SCN3A,SMC4,FAM69A,HN1L,DCHS1,COX11,CR2,LRRC1,PRRC1,LDB2,SLC25A5,NMT2,CYB5A,ULK2,PRIM1,NCOA3,BTG1,PIK3C2B,RPL22,TOB1,RARG,PKIA,FAM134B |
| 2.302e-04 | -8.38 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | 147 | 38 | 17758 | 2588 |
PRSS8,RUNX2,S100A11,PTTG1,ERI2,C5orf30,MORC4,NUF2,NENF,DDR1,CYP39A1,BEX2,SIRPA,IER3,PDGFA,CCND1,BTG3,XYLT2,BMP7,AKR1B1,TAX1BP3,TAGLN2,ACSL4,PTPRE,TLE6,WBP5,HMMR,PSRC1,ACBD3,PLS1,TANC1,CD40,NPDC1,TCEAL8,DNAJC10,ABCB1,ANXA9,FGD1 |
| 2.307e-04 | -8.37 | Regulation of PLK1 Activity at G2/M Transition | REACTOME pathways | R-HSA-2565942 | 81 | 25 | 8202 | 1235 |
PLK1,CEP70,PPP1R12A,TUBB4B,CUL1,PRKAR2B,CCNB1,BORA,PRKACA,CDK1,OPTN,CKAP5,CNTRL,CENPJ,CEP78,PLK4,NEK2,PPP1CB,AURKA,TUBG1,SSNA1,NDE1,CEP41,CCNB2,TUBA4A |
| 2.315e-04 | -8.37 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | 595 | 118 | 17758 | 2588 |
CCNE2,AVPI1,DLGAP5,NQO1,HOXB7,CUL4B,EPHX4,KIF2C,LACTB2,CCNB1,DPP8,STIL,CENPN,TNFSF9,FANCI,SS18,BTG3,PCNA,CCNA2,IL6ST,FRYL,KIF14,OSBPL3,PHTF1,TUBG1,GOT1,STEAP3,HYLS1,RNASEH2A,MYBL1,ODF2L,IL1RAP,CKS2,SOAT1,SGCE,PSRC1,FIGNL1,AGPS,OSTM1,PBK,ITCH,BNIP3L,NUSAP1,ROR1,ANLN,CDK1,TRUB1,SFXN1,DNAJC10,IDE,RBL1,DNM1L,ZNF367,P4HA2,SIPA1L1,KPNA2,C1orf43,DENND5B,MRPS9,FAM89A,ENO2,CKAP2,CIT,MAN1A2,PRKAA1,RACGAP1,GPR180,GPSM2,CHAC2,TIPRL,SSX2IP,KIF5B,SNX13,RALGPS2,CTSC,TOX2,PRC1,CKS1B,TNFRSF12A,USP1,HSPA13,KNTC1,IQGAP3,LRIF1,SGCB,PSMA5,CCDC88A,MSH6,SMC4,GFPT1,ZWINT,HPS3,PLAUR,CCDC34,AK4,KIF20B,AP1AR,TMEM30A,KBTBD2,DCUN1D1,NETO2,OSMR,AURKA,NXPH4,DONSON,CTSA,PPP2R3C,ATP1B3,SPCS3,PLOD3,NDE1,ATP6V1C1,ARSB,UBE2C,CBX5,ACOT7,USP16,EGLN1 |
| 2.316e-04 | -8.37 | SHANK1 (SH3 and multiple ankyrin repeat domains 1) | protein interactions | 50944 | 19 | 10 | 16036 | 2547 |
DLGAP1,RPS6KA2,ARHGEF7,SHARPIN,STAT1,DNM2,TANC1,ABCA1,ADGRB2,RPS6KA3 |
| 2.326e-04 | -8.37 | TRIM8 (tripartite motif containing 8) | protein interactions | 81603 | 52 | 19 | 16036 | 2547 |
PCGF5,TRIM8,TRIM2,TRIM24,RC3H2,XIAP,TP53,RNF113A,CBL,PIAS3,TRIM9,TRIM47,PTEN,MKRN3,UBE2D2,OTUB2,TRIM21,MAP3K7,TRAF5 |
| 2.337e-04 | -8.36 | SIMBULAN_PARP1_TARGETS_DN | MSigDB lists | SIMBULAN_PARP1_TARGETS_DN | 17 | 9 | 17758 | 2588 |
SPP1,PCNA,CCNA2,CDC20,TAGLN2,CCNB1,NCAM1,CCNB2,PRIM1 |
| 2.337e-04 | -8.36 | ONDER_CDH1_TARGETS_3_UP | MSigDB lists | ONDER_CDH1_TARGETS_3_UP | 17 | 9 | 17758 | 2588 |
MAGED2,ALDH6A1,WIPI1,TSC22D3,CRIP2,KDELR3,KLF9,LEPR,CYP1B1 |
| 2.338e-04 | -8.36 | stress-activated MAPK cascade | biological process | GO:0051403 | 129 | 35 | 16441 | 2455 |
TAOK2,TAB3,RPS6KA1,CCM2,CUL1,PKN1,TNFRSF19,RPS6KA2,IRAK1,MAP3K9,DUSP10,DAB2IP,MDFIC,MAPK11,MAP3K7,MAPK7,SYK,MDFI,RIPK2,MAPKAPK3,PTGER4,ELK1,DUSP4,FOS,MAP3K6,MAPK8IP1,MAPKAPK2,SH2D3C,MAP3K11,NOD2,KIAA1804,MAP3K5,PPP2R5D,GAB1,RPS6KA3 |
| 2.350e-04 | -8.36 | KEGG_INSULIN_SIGNALING_PATHWAY | MSigDB lists | KEGG_INSULIN_SIGNALING_PATHWAY | 137 | 36 | 17758 | 2588 |
PRKAA2,ACACB,SLC2A4,SORBS1,TRIP10,INPP5D,PRKAA1,FLOT1,CALM3,PRKACA,CALM2,SHC3,PRKCI,PIK3CA,GYS1,PIK3CD,PPP1CA,PHKA2,FLOT2,PHKG2,AKT1,PIK3R1,CALM1,PYGL,PRKAR2B,ELK1,CBL,RHEB,SOCS3,PTPRF,IRS2,TSC1,INSR,PRKAG2,PPP1CB,PRKAR1A |
| 2.350e-04 | -8.36 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological process | GO:0031659 | 8 | 6 | 16441 | 2455 |
PKD2,ADAM17,PIM1,AKT1,EGFR,RGCC |
| 2.365e-04 | -8.35 | protein localization to lysosome | biological process | GO:0061462 | 20 | 10 | 16441 | 2455 |
NAGPA,ZFYVE16,GCC2,SCARB2,RNF128,GNPTAB,SH3BP4,SORL1,SNX16,CD81 |
| 2.379e-04 | -8.34 | Thioredoxin_CS | interpro domains | IPR017937 | 17 | 9 | 18293 | 2672 |
DNAJC10,TXN,P4HB,TMX4,PDIA5,PDIA3,PDIA6,TMX1,PDIA4 |
| 2.394e-04 | -8.34 | GSE360_CTRL_VS_L_DONOVANI_DC_DN | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_DC_DN | 194 | 47 | 17758 | 2588 |
KLK10,TXN,IL15RA,ENO2,GCAT,NDRG1,DUSP5,NRP2,IER3,PHYHIP,TYMP,LYPD3,AKR1B1,ATP8B1,NFKB2,APOBEC3G,SLC16A5,LAMP3,MX1,RASGRF1,MBP,SLC39A8,LITAF,GRIN1,ACO1,EMP3,AURKB,VCP,CYB5A,CD83,HSF4,IRS2,BTG1,SCARB2,CASP7,ETS2,FGFR2,NFKBIA,TDRD7,SSNA1,UNC5B,WDR62,JAK3,NR3C2,AHR,ACOT7,EHD1 |
| 2.394e-04 | -8.34 | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDM_DN | 194 | 47 | 17758 | 2588 |
GCLM,GOLIM4,DHPS,FRMD6,CD82,SLC25A13,SOD2,EFHD2,IL18,REPS1,SPTB,RAD23A,NOV,ADRBK1,PIK3AP1,LMO4,BHLHE41,CDH3,MDFIC,ALDH7A1,TAGLN2,CTTN,WBP4,PTPRE,MYLIP,CPD,PPIF,MOB4,STAU2,NUBP1,MAP3K6,PSMA4,LEPR,ZMPSTE24,IRX3,SFXN1,BFSP1,AREG,PVRL2,PLK2,TBX1,CGREF1,TDRD7,MAP3K5,TTC39C,SRSF9,HOXC13 |
| 2.400e-04 | -8.33 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 163 | 41 | 17775 | 2585 |
CD99,SPRED1,LZTFL1,GRIK2,IL15,PRKAA1,HAL,TP53,COL18A1,SEPT4,MICALL2,FLT3,DDR1,RB1,RPS6KA2,MUC4,CTNNB1,CTGF,PTEN,STEAP2,PIM1,RAG1,SYK,IL1RAP,MSH6,NR3C1,PARD3B,MYBL2,OGDHL,TCF7,YES1,SESN1,PRDM11,ARHGAP24,BTG1,FYN,JAK1,SHROOM3,JAK3,NR3C2,CAPN1 |
| 2.403e-04 | -8.33 | vasculature development | biological process | GO:0001944 | 462 | 97 | 16441 | 2455 |
ACVR1,PAX6,HSPG2,EPAS1,FOXM1,COL18A1,IL18,EGR3,VASH1,PDGFB,PDGFA,TYMP,NOV,CTNNB1,CTGF,PIK3CA,SMO,DAB2IP,EPHB4,NOTCH3,TIPARP,LOXL1,CYP1B1,MAP3K3,SIRT1,SMARCA2,AKT1,FZD4,SAT1,HTATIP2,LOXL2,ZFAND5,EDNRA,SOCS3,PGF,PTGS2,HS6ST1,PTPRJ,HPSE,TBX1,MYLK,PNPLA6,KLF5,PLXND1,UNC5B,E2F8,NKX3-1,ADGRG1,CCM2,TGFBR1,ETS1,SRPX2,NRP2,GBX2,SGPL1,E2F7,PDCD10,ITGB8,PTEN,CYR61,GPC3,BAX,ADAM15,ACTA2,TNFRSF12A,MYDGF,MAP3K7,SGCB,SYK,TMED2,HES1,ELK3,NR4A1,RAPGEF2,CALCRL,EPHA1,RHOB,RASA1,GPLD1,ARHGAP24,ACVRL1,SCG2,FGFR2,PRCP,ITGA7,PLPP3,FGF18,ERAP1,EGFL7,PKD2,HOXB13,EFNA1,ITGAV,FZD5,ZMIZ1,OSR1,AHR |
| 2.403e-04 | -8.33 | regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000045 | 144 | 38 | 16441 | 2455 |
PSME2,CUL4B,CTDSPL,PSMD7,TP53,PSMD10,PSME1,TP73,CCND1,E2F7,RB1,CYP1A1,PSMD1,PTEN,DACT1,KIF14,PSMC2,FBXO7,BRD7,CDKN1B,KANK2,PIM1,CTDSP2,PSMA5,ADAM17,AKT1,PSMB4,RGCC,PSMA4,EGFR,JADE1,TJP3,PSMD3,E2F1,PKD2,FHL1,PSMC1,CTDSP1 |
| 2.443e-04 | -8.32 | REACTOME_KINESINS | MSigDB lists | REACTOME_KINESINS | 24 | 11 | 17758 | 2588 |
KIF5B,KIF3C,KIF20A,KLC2,KLC3,KIF23,KIF22,RACGAP1,KIF2C,KIF11,KIF26A |
| 2.443e-04 | -8.32 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | MSigDB lists | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | 24 | 11 | 17758 | 2588 |
MYL9,RAC2,RHOA,ARHGEF11,SEMA4D,LIMK1,ERBB2,MYH14,MYL12B,RHOB,RND1 |
| 2.450e-04 | -8.31 | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | 168 | 42 | 17758 | 2588 |
LAMP1,PAPSS2,CDKN1C,EPS8,ASAH1,FAM102B,COL4A5,NOTCH2,TNFRSF19,CMTM6,CORO1B,FAM46A,PIK3AP1,CTSC,SNX18,CST3,NPTN,PTPN18,MARK1,AGPS,MAPKAPK3,SH3BGRL,S100A4,LITAF,CAPNS1,NPC2,DUSP4,ZFAND5,ZNF618,PSMA4,RHOB,DZIP1L,NAAA,ZNF628,ALDH3B1,TWSG1,PLOD2,SECTM1,NR4A3,ARPC2,ARF6,SLC31A2 |
| 2.459e-04 | -8.31 | RADAEVA_RESPONSE_TO_IFNA1_UP | MSigDB lists | RADAEVA_RESPONSE_TO_IFNA1_UP | 52 | 18 | 17758 | 2588 |
MX1,CASP3,PLSCR1,IFITM3,HLA-E,PRKCQ,PSME1,LGALS3BP,CALR,CASP7,BAX,STAT1,CDKN1B,IRF7,HLA-C,IFIT1,IFI6,IRF1 |
| 2.463e-04 | -8.31 | V$HNF4_01_B | MSigDB lists | V$HNF4_01_B | 237 | 55 | 17758 | 2588 |
USH1C,PNPLA2,TP53,C6orf106,ERBB2,NRG2,CALM3,MPP5,TEX2,CRABP2,DOCK11,SEPP1,PRKACA,FBLN1,XPR1,CALM2,AIM1L,RAB15,CYP1A1,IGF1R,CDK16,KLF3,FUT8,DAB2IP,CRY2,TSPAN13,NR2C1,LAMP2,GCC2,TGIF1,MLEC,AGPS,ASXL1,NR4A1,SERTAD4,CALM1,PPARA,RHOB,EBF2,CDK5R1,MAP1B,TRIM47,MPRIP,INSR,HOXA9,MAP3K11,NXPH4,TLE1,MRPS28,SPRY4,UNC5B,REEP4,ACOT7,DIS3L,EHD1 |
| 2.473e-04 | -8.30 | TPR-contain_dom | interpro domains | IPR013026 | 127 | 34 | 18293 | 2672 |
TTC8,ST13,CEP70,TMTC3,DNAJC3,KLC2,ERCC6L,WDTC1,GPSM2,AIP,APPBP2,TTC21B,NOXA1,TRANK1,FICD,KLC3,IFIT1,TMTC1,LONRF3,TTC7A,EMC2,TANC1,NPHP3,IFIT3,TMTC2,UNC45B,SPAG1,RGPD5,PEX5,TTC12,P4HA2,CABIN1,TTC9,TANC2 |
| 2.477e-04 | -8.30 | Synthesis of IP3 and IP4 in the cytosol | REACTOME pathways | R-HSA-1855204 | 27 | 12 | 8202 | 1235 |
CALM2,PLCH1,PLCG1,INPPL1,PTEN,INPP5D,OCRL,PLCG2,CALM1,CALM3,ITPKA,PLCB2 |
| 2.477e-04 | -8.30 | Sema4D in semaphorin signaling | REACTOME pathways | R-HSA-400685 | 27 | 12 | 8202 | 1235 |
MYL9,RAC2,RHOA,ARHGEF11,SEMA4D,LIMK1,ERBB2,MYH14,MYL12B,RHOB,RND1,ARHGAP35 |
| 2.479e-04 | -8.30 | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 189 | 46 | 17758 | 2588 |
RUSC2,ASL,OSGIN2,RASGRP3,PSME1,KBTBD11,MAP1LC3B,MXD1,ZFYVE16,FRY,TM9SF2,RALB,PLCG2,SLC44A1,PPP4R1,OPN3,DRAM1,BRD7,MANF,MARCH2,PTPRE,SMC4,PDGFC,RHOA,ALDH2,TCEB2,CDA,MGAM,YES1,ESYT1,ATP10D,ZDHHC3,BCAR3,HLA-B,SWAP70,PPP2R5A,AREG,CDK19,KBTBD2,CSF1,ZDHHC7,ZMIZ1,CHPT1,SERPINB1,RRAGD,CD33 |
| 2.479e-04 | -8.30 | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDM_UP | 189 | 46 | 17758 | 2588 |
KCNAB3,PTTG1,ETNK1,OSGIN2,C5orf30,HMGN3,NOTCH2,CHAC2,CACNB4,PCBP1,SLC35E4,B4GALNT1,CDKN2C,TFAP4,PDGFA,H2AFY,TRIM21,SGK1,CTTN,PIM1,TFG,BTBD3,TIAM1,ODF2L,DVL2,FAH,PPIF,ARAP2,PTGER4,AKAP3,IFIT3,CD40,CASP4,PRX,NFIX,ENDOD1,HLA-B,ACADSB,PVRL2,NAT1,CSF1,MYLK,STK39,PLOD3,IFIH1,DMPK |
| 2.479e-04 | -8.30 | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 189 | 46 | 17758 | 2588 |
PACSIN2,NLRX1,ASAH1,FTH1,SAMD9,NOTCH2,SNN,KBTBD11,ARHGEF40,IL18R1,CMTM6,APLP2,TYMP,PTEN,RALB,BCL6,ACSL4,PTPRE,CKAP4,MYO5A,MAP3K3,ORAI2,CD55,MBP,TCEB2,MAPKAPK3,TACC1,CTNNAL1,CDA,HMG20B,MGAM,ERP44,FOS,GABARAPL1,FUCA1,SWAP70,AREG,ANKRD6,PELI2,NMI,PNPLA6,FGD6,ZDHHC7,ZMIZ1,JARID2,EHD1 |
| 2.479e-04 | -8.30 | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN | MSigDB lists | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN | 189 | 46 | 17758 | 2588 |
DDX58,PARP12,GNPDA1,PARP14,TRIM5,PSME2,TAP1,SMARCAL1,HERC5,SAMD9,HERC6,LGALS3BP,SAC3D1,DTX3L,RB1,PIK3AP1,RALB,METTL7A,IFIT1,OAS3,ALDH3A2,PARP9,LAMP3,MX1,HN1L,IFITM3,LAP3,USP18,MBNL3,BLVRA,SNTB1,IFIT3,IDH1,ATP10D,GLCE,SCARB2,IDE,TRIM69,STAT1,TDRD7,IRF7,CMPK2,SLC27A3,IFIH1,IFI6,CPPED1 |
| 2.491e-04 | -8.30 | Integrated Breast Cancer Pathway | WikiPathways | WP1984 | 152 | 42 | 4455 | 729 |
GRN,CASP3,TP53,TGFBR1,RASGRP3,BARD1,CCND1,RB1,WEE1,NOXA1,CTNNB1,CDH1,PTEN,BAX,MSH2,SELK,USP38,RASGEF1A,MYT1,APOBEC3G,NUP85,MSH6,SIRT1,PLK1,AKT1,CASP9,DAG1,RHEB,EGFR,NCOA3,TSC1,JAK1,E2F1,STAT1,AURKA,DHTKD1,HDAC1,XRCC3,ZMIZ1,AHR,PKIA,USP16 |
| 2.495e-04 | -8.30 | blood coagulation | biological process | GO:0007596 | 525 | 108 | 16441 | 2455 |
PLA2G4A,MYL9,KIF3C,PAPSS2,INPP5D,KLC2,TP53,DGKA,GATA3,F11R,ITPR2,KIF2C,PRKACA,KIF26A,PDGFB,PDGFA,CALM2,WEE1,STIM1,CYP4F11,PLCG2,PIK3CA,IRF2,KIF22,LMAN1,F2R,RASGRP1,TUBA4A,LAMP2,ENPP4,SOD1,AKT1,PRKAR2B,PRKCQ,F12,ATP1B1,CD40,ITPR3,MYL12A,PLCG1,FYN,KCNMB4,ABHD12,AXL,HDAC1,HSPB1,F2RL1,MAFF,PRKAR1A,SERPINE2,CD63,ITGA6,DGKQ,HABP4,SELL,KIF23,CALM3,RACGAP1,DOCK11,FBLN1,MERTK,ITGA2B,FZD6,SIRPA,RAC2,ITGA3,TIMP1,GATA2,CD9,PRKG1,AK3,WNT3A,DGKG,SYK,ATP2B1,RHOA,PLSCR1,PLAUR,CALM1,ANO6,PIK3R1,HMG20B,C1GALT1C1,PDE5A,YES1,ILK,BCAR1,KIF11,GNA11,RHOB,DGKE,PDE11A,RASGRP2,DGKH,GNAS,SERPINA1,PRCP,ITPR1,ARRB1,CENPE,ITGAV,ATP1B3,CBX5,TRPC3,L1CAM,DOCK9,IRF1,EHD1 |
| 2.509e-04 | -8.29 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | 221 | 52 | 17758 | 2588 |
CCNE2,SLC25A24,FARP1,LRRFIP2,CD82,BLVRB,RET,PLAC1,EGR3,SYTL4,PLA2G16,PHLDA1,IL17RB,TFAP4,B3GALNT1,PCNA,KCNK5,SGK3,OPN3,SGK1,FAM102A,OSTF1,TMEM64,MYBL1,TIAM1,TIPARP,ALDH3A2,SEMA3B,PPIF,CELSR2,USP31,PRSS23,SYBU,ASB13,COL12A1,SEC14L2,PRIM1,ENDOD1,TMEM164,AREG,RBL1,PLOD2,ZNF367,LRIG1,NAB2,E2F1,RAB31,XRCC3,ANXA9,GLA,PTGES,ISOC1 |
| 2.513e-04 | -8.29 | KESHELAVA_MULTIPLE_DRUG_RESISTANCE | MSigDB lists | KESHELAVA_MULTIPLE_DRUG_RESISTANCE | 79 | 24 | 17758 | 2588 |
CCDC109B,TRAPPC10,SLC25A13,IQGAP1,BLVRB,CRIP2,NDRG2,BCL7B,PCTP,BCAP31,CASP4,PHF1,CCDC92,MAGOHB,CDKN2C,C16orf59,TBX1,ADAM15,HDAC1,MARCH2,HSPB1,MAPK12,DOCK9,NXT2 |
| 2.513e-04 | -8.29 | MORI_PRE_BI_LYMPHOCYTE_UP | MSigDB lists | MORI_PRE_BI_LYMPHOCYTE_UP | 79 | 24 | 17758 | 2588 |
HMMR,TXN,TUBB4B,CDC20,CDCA3,RACGAP1,MGST2,H2AFV,CDK1,PRDX4,TOP2A,IDE,CDCA5,DBI,PRC1,CKS1B,AURKA,KPNA2,UBE2C,CCNB2,KANK3,E2F8,MELK,SMC4 |
| 2.551e-04 | -8.27 | BROWNE_HCMV_INFECTION_20HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_DN | 98 | 28 | 17758 | 2588 |
HMMR,LTBP1,FARP1,TRIM2,NQO1,ALDH6A1,ACO1,DIAPH2,SRPX2,NMT2,TRAM2,ST5,TGFBR3,ADD3,ITGA3,FRY,CTGF,WIPI1,RND3,NR1D2,AXL,SIPA1L1,ATP13A3,MAP3K5,ETHE1,F2R,AHR,ATP2B1 |
| 2.551e-04 | -8.27 | soft_tissue-striated_muscle-rhabdomyosarcoma-sclerosing | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-sclerosing | 61 | 20 | 17775 | 2585 |
ARAP3,AKT1,RET,PIK3R1,TP53,ASL,ERBB2,IDH1,GNA11,EGFR,FRMD4B,GNAS,ZYX,CTNNB1,FGFR2,ITGA7,PIK3CA,TMEM143,SMO,NGEF |
| 2.564e-04 | -8.27 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN | 184 | 45 | 17758 | 2588 |
TTC8,BIN1,PINK1,PARP14,ITGA6,MCTP2,SWI5,PKP2,GTF3A,FBXO6,ETS1,PRKACA,VPS26A,APOBEC3B,SESN3,SH3BP1,RINL,RUNDC3B,SLC35B4,KLC3,CCDC82,RP2,IFIT1,PIK3CD,MARCH2,TMEM8A,LRIF1,C12orf75,FLOT2,RPGR,RASGRP1,SSH3,VAMP3,FBXO8,UBAC1,GLO1,ASB13,ULK2,NEIL1,FNTA,SPINT2,ABCB1,IRF7,SERPINB6,TMEM14A |
| 2.579e-04 | -8.26 | MODULE_252 | MSigDB lists | MODULE_252 | 232 | 54 | 17758 | 2588 |
CCNE2,PAX6,FOXM1,SOX9,PTTG1,NDC80,CCNO,KIF23,PSMD10,KIF2C,CCNB1,BARD1,PHLDA1,RAD23A,TOP2A,CDKN2C,APLP2,WEE1,PCNA,HSF2,CCNA2,NEK2,MSH2,GTF2F2,BUB1,KNTC1,NEK4,PLK1,ZWINT,CENPA,AKT1,PAPD7,MYBL2,UBE2A,FOS,CDC25C,CDK1,PSMA4,DDX23,PRIM1,MAP2,DCK,STK38,STAT1,E2F1,HDAC1,XRCC3,CENPE,CCNB2,CBX5,PPP2R5D,CBX4,CSRP2,RAD21 |
| 2.579e-04 | -8.26 | CYTOSKELETAL_PART | MSigDB lists | CYTOSKELETAL_PART | 232 | 54 | 17758 | 2588 |
MYL9,LASP1,KIF3C,BMF,SORBS1,DLGAP5,IQGAP1,KLC2,KIF23,KIF2C,CNTROB,HDAC6,SPTB,APPBP2,SAC3D1,CKAP5,ATG4A,KIF5B,TOP2A,CNTRL,CABP1,TUBGCP6,TBCD,CAPG,PRC1,NEK2,TUBG1,BUB1,ESPN,KNTC1,CLIP2,ATG4D,PLK1,PCGF5,UXT,CDC20,EZR,KIF20B,ANLN,KIF11,MYOM1,CDK1,RANBP9,MAP1B,NIN,TSC1,MAP2,MAP3K11,AURKA,CEP41,NDE1,ARPC2,SHROOM2,ESPL1 |
| 2.587e-04 | -8.26 | pancreas-other-dysplasia-in_situ_neoplasm | COSMIC cancer mutations | pancreas-other-dysplasia-in_situ_neoplasm | 48 | 17 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,JAK3 |
| 2.587e-04 | -8.26 | dysplasia-in_situ_neoplasm | COSMIC cancer mutations | dysplasia-in_situ_neoplasm | 48 | 17 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,JAK3 |
| 2.611e-04 | -8.25 | pituitary-adenoma-non_functioning | COSMIC cancer mutations | pituitary-adenoma-non_functioning | 14 | 8 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,CDH1,RET,PIK3CA,PRKAR1A |
| 2.611e-04 | -8.25 | ACTH | COSMIC cancer mutations | ACTH | 14 | 8 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,CDH1,RET,PIK3CA,PRKAR1A |
| 2.611e-04 | -8.25 | pituitary-adenoma-ACTH | COSMIC cancer mutations | pituitary-adenoma-ACTH | 14 | 8 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,CDH1,RET,PIK3CA,PRKAR1A |
| 2.618e-04 | -8.25 | MAPK3 (mitogen-activated protein kinase 3) | protein interactions | 5595 | 209 | 53 | 16036 | 2547 |
ELK4,DHPS,RPS6KA1,IQGAP1,RET,TP53,SORBS3,HDAC6,ZNF219,ETS1,DUSP5,TTYH3,IER3,FOXP2,RPS6KA2,ADRBK1,PAK2,DAPK1,DUSP10,ADAM15,PPP1CA,PTPRE,SYK,METAP2,DUSP1,HMMR,TGIF1,MBP,SYNE2,CASP9,PPARA,SCRIB,DUSP4,ELK1,PNKD,CDC25C,VCP,MAPKAPK2,HSF4,PTGS2,INSR,ATP1A1,CCDC6,PRDX3,MYLK,NAB2,DCUN1D1,RYK,ARRB1,GAB1,NUP58,RPS6KA3,ZC3HC1 |
| 2.647e-04 | -8.24 | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP | MSigDB lists | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP | 179 | 44 | 17758 | 2588 |
CASP3,RBM24,ADD1,CUL4B,CCM2,SMARCAL1,GMPR,IL13RA1,MRAS,SAMD9,DOCK11,TRIB2,SLC25A43,PPP2R3A,LMNA,EPDR1,CKAP5,ZDHHC21,MARCH8,CD46,DOPEY2,RALB,PLCG2,DDHD2,SLC44A1,ECI2,ACTA2,ZNF230,RCAN3,PARP9,OLFML2A,KIAA1841,SNTB2,CLSTN1,ILK,LHFPL2,FECH,NT5C2,TMEM164,C19orf66,STAT1,FAM195A,LTA4H,AHR |
| 2.651e-04 | -8.24 | KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES | MSigDB lists | KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES | 14 | 8 | 17758 | 2588 |
B3GALNT1,FUT2,A4GALT,HEXB,FUT1,GLA,ST3GAL1,NAGA |
| 2.651e-04 | -8.24 | ENDOPLASMIC_RETICULUM_LUMEN | MSigDB lists | ENDOPLASMIC_RETICULUM_LUMEN | 14 | 8 | 17758 | 2588 |
CALR,RCN1,HSP90B1,PDIA5,ERAP1,ERP44,ERAP2,PDIA4 |
| 2.651e-04 | -8.24 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | MSigDB lists | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | 14 | 8 | 17758 | 2588 |
DPYSL5,FYN,DPYSL2,PLXNA1,DPYSL4,SEMA3A,CDK5R1,DPYSL3 |
| 2.687e-04 | -8.22 | GTGGGTGK_UNKNOWN | MSigDB lists | GTGGGTGK_UNKNOWN | 276 | 62 | 17758 | 2588 |
DOC2A,SORBS1,RUNX2,TMEM184B,IGFBP6,CDH22,THRA,UBASH3B,ARFGEF1,CALM3,PHOSPHO1,TGFBR1,FAM91A1,EGR3,NOTCH2,BAHD1,PDGFB,SPTB,KREMEN1,BCAP31,PER2,CALM2,TFAP4,PHYHIP,ADD3,FUT2,ZCCHC12,MITF,CDKN1B,TWIST1,ABCD1,ACSL4,SLC12A2,SCYL3,TSPAN33,SEMA3B,SIRT1,ATL1,CAPN6,ACVR1C,NR3C1,DEPDC4,LYRM1,CALM1,PANK1,EPHA1,CLCN2,SP4,PRX,RASA1,PGF,PITX2,KLF12,TMEM54,TRAF3IP1,ITPR1,NR4A3,OTUB2,CTNND1,ARPC2,NRGN,KLF7 |
| 2.690e-04 | -8.22 | SH3_9 | pfam domains | PF14604 | 77 | 24 | 16629 | 2504 |
BIN1,LASP1,SORBS1,SH3D19,UBASH3B,SORBS3,MAPK8IP1,ARHGEF16,SH3KBP1,ARHGEF26,SH3RF2,ARHGAP42,ARHGEF19,SNX18,FUT8,SH3BP4,MAP3K11,MAP3K9,KIAA1804,SH3GLB2,CTTN,PACSIN1,NEB,RUSC1 |
| 2.690e-04 | -8.22 | KEGG_SMALL_CELL_LUNG_CANCER | MSigDB lists | KEGG_SMALL_CELL_LUNG_CANCER | 84 | 25 | 17758 | 2588 |
CCNE2,AKT1,TRAF2,ITGA6,CASP9,PIK3R1,XIAP,TP53,BCL2L1,ITGA2B,CCND1,PIAS3,RB1,PTGS2,ITGA3,PTEN,NFKBIA,E2F1,PIK3CA,PIAS2,CKS1B,CDKN1B,ITGAV,PIK3CD,TRAF5 |
| 2.707e-04 | -8.21 | epithelial tube formation | biological process | GO:0072175 | 125 | 34 | 16441 | 2455 |
CTHRC1,GRHL2,ST14,SOX9,SDC4,RET,RAB23,GATA3,NCKAP1,PRKACA,STIL,FZD6,VASP,CTNNB1,LMO4,TWIST1,MAP3K7,DVL2,TGIF1,SALL4,PRICKLE1,KIF20B,SCRIB,BCL10,ARHGAP35,IRX3,TSC1,SHROOM3,PTK7,SPINT2,SOX8,OSR1,COBL,RARG |
| 2.707e-04 | -8.21 | mucopolysaccharide metabolic process | biological process | GO:1903510 | 125 | 34 | 16441 | 2455 |
SLC35D2,AGRN,HSPG2,IL15,XYLT1,HEXB,SDC4,B4GALT4,DSE,SDC1,CHST2,CHPF,GNS,GPC3,IMPAD1,XYLT2,GALNS,PIM1,CHP1,B3GALT6,CHSY3,HMMR,B3GNT7,B3GNT2,AKT1,GUSB,GLCE,CSGALNACT1,GLB1,B4GAT1,B4GALT3,ARSB,ST3GAL1,NDST3 |
| 2.716e-04 | -8.21 | GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN | 195 | 47 | 17758 | 2588 |
GRN,LGALS3,S100A11,CTSB,HEXB,ASAH1,KCTD12,NOTCH2,ARHGEF40,SIRPA,ARHGEF10L,GNS,APLP2,ATP6V0B,TNS3,MGAT1,SLC16A6,CAPG,BCL6,DAPK1,MTMR11,PTPRE,SNX10,SYK,CCDC88A,CKAP4,GCA,MCTP1,TIMP2,PLSCR1,VAMP3,DIAPH2,NPC2,PCTP,ZFAND5,ADRBK2,STX3,MID1IP1,RBM47,CORO1C,NOD2,ARAP1,GLB1,ZMIZ1,SLC31A2,SLC27A3,CD33 |
| 2.725e-04 | -8.21 | ENK_UV_RESPONSE_KERATINOCYTE_UP | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_UP | 521 | 105 | 17758 | 2588 |
CCNC,CCNI,KLK10,S100A11,TUBB4B,BLCAP,PSME1,MAP1LC3B,PCBP1,GNB2,TNFSF9,MXD1,IER3,ATP6V0B,BTG3,RGS12,CTGF,P4HB,ZFP36,CAPG,AKR1B1,VAT1,CLDN4,TACSTD2,ACOX2,PPP1CA,TECR,LGMN,TSPAN1,PTPRE,SULT2B1,GPX4,CTH,PPIF,TCEB2,DRAP1,CDA,STK17B,VCP,AREG,OVOL1,ZNF165,KLF5,EIF4EBP2,SERPINB6,MAPK13,GLA,HSPB1,F2RL1,MAFF,GRN,PRSS8,CD99,CDKN1C,IGFBP6,HLA-E,HLA-F,DNAJB2,BLVRB,SDC4,ASL,SORBS3,PLD2,CRABP2,GSTP1,EFNB1,DUSP5,HLA-A,SNTA1,VASP,CYR61,CDK16,LYPD3,SGK1,TAGLN2,HLA-C,CTSD,CITED2,SPRY2,PHKG2,DUSP1,TGIF1,PSMB4,FHL2,HMG20B,EMP3,FOS,GNAS,MAGED2,GALNT3,NUCB1,BTG1,RPL12,ETS2,PVRL2,RND3,DHRS2,ITPR1,NR4A2,EFNA1,PLD1,HMGA1,GEM,PLIN3,TOB1 |
| 2.729e-04 | -8.21 | V$AP2REP_01 | MSigDB lists | V$AP2REP_01 | 174 | 43 | 17758 | 2588 |
IER5L,ACVR1,NKX3-1,NFKBIE,DDIT4L,WDTC1,IRX4,CALM3,CBLL1,TEX2,MORF4L2,GNB2,EFNB1,LTBP3,FANCI,AKIRIN1,CALM2,PAK6,SH3D21,IRAK1,CYR61,CALD1,ATP5H,ZIC5,TNPO2,TACSTD2,MAST4,DNAI1,AMFR,CALM1,PANK1,NKAIN1,EPHA1,EBF2,RAP2C,BMP1,NRG1,EFNA5,C1orf43,RPL22,NR3C2,COBL,COL16A1 |
| 2.742e-04 | -8.20 | human chrXq22 | chromosome location | human chrXq22 | 18 | 8 | 26250 | 2805 |
FRMPD3,HNRNPH2,TSPAN6,COL4A5,MORF4L2,GLA,DRP2,BEX2 |
| 2.763e-04 | -8.19 | REACTOME_SIGNALING_BY_PDGF | MSigDB lists | REACTOME_SIGNALING_BY_PDGF | 118 | 32 | 17758 | 2588 |
COL9A3,CALM3,COL4A5,ITPR2,PHLPP1,PRKACA,PDGFB,CALM2,PDGFA,SPP1,ADRBK1,PTEN,COL6A1,PIK3CA,CDKN1B,PDGFC,COL6A2,AKT1,NR4A1,CASP9,CALM1,PIK3R1,FURIN,PRKAR2B,ITPR3,BCAR1,CDK1,RASA1,PLCG1,STAT6,STAT1,PRKAR1A |
| 2.767e-04 | -8.19 | negative regulation of cellular metabolic process | biological process | GO:0031324 | 2309 | 401 | 16441 | 2455 |
ACACB,TXN,PPP4R4,TRIM24,LGR4,IBTK,TSC22D3,DNAJC3,XIAP,GATA3,PSME1,MORF4L2,CCNB1,BARD1,RIC1,PHF1,TP73,CALM2,CDKN2C,PSMD1,ZFP36,RGS3,FOSB,IRF2,CRY2,ZBTB18,APOBEC3G,SMARCA2,TNIP1,PBK,UXT,CDYL,CDA,TFAP2C,AGO4,PRKAR2B,LOXL2,PIF1,AURKB,POR,AHRR,PIAS3,ENPP1,CAMK2N2,LIMK1,TRAF3IP1,PPP2R4,PRDM5,NOD2,HDAC1,SERPINB6,EIF4EBP2,SERPINI1,SPRY4,HSPB1,F2RL1,E2F8,LZTS1,CDKN1C,SOX9,PRKAA1,RAB23,SH3RF2,MECOM,ELF3,TFAP4,CALR,PAIP2B,BHLHE41,FBXO7,MSH2,DAPK1,SORL1,MAPK7,DLX4,SOCS5,QSOX1,SALL4,CALM1,FHL2,WHSC1,EPHA1,ILK,KDM3A,PSMA4,NFIB,PLIN5,FAS,AP1AR,PRKAG2,ETS2,HTT,SEMA4D,NAB2,PIAS2,SFMBT1,NR4A2,STK39,EFNA1,PER3,CBX5,SERPINB1,RPS6KA3,XDH,EGLN1,IRF1,ELK4,SPRED1,TCF25,S100A11,THRA,INPP5D,RPS6KA1,CAST,SUZ12,IQGAP1,PTTG1,WDTC1,BCL2L1,CCND1,CD46,APLP2,SP100,DACT1,CDKN1B,DAB2IP,PDE4D,DLG3,CDKN2D,NR2C1,RNF169,CAMSAP3,APOBEC3D,DMTN,DRAP1,COX11,RAD17,PKMYT1,H2AFV,SNX12,NFIX,IRS2,FYN,PPP2R5A,WFS1,CORO1C,WWTR1,STAT1,SLC27A1,KLF5,NRG1,RGS14,CBX7,PRKAR1A,FARP1,TNRC6C,NKX3-1,DEPDC1,TRAF2,APOBEC3H,PKN1,ZNF219,GSTP1,TIPRL,FGF19,SIX4,WWP2,CTNNBIP1,SNTA1,E2F7,IRAK1,RNF128,PTEN,GPC3,CST3,BAX,ATP8B1,TMBIM6,WWP1,CITED2,CNOT6L,RAG1,GFI1,SPRY2,TRIM62,NCOA2,CRTAP,MSH6,TGIF1,RAPGEF2,FURIN,GPLD1,CDK5RAP1,PITX2,TIMP3,FGFR2,ACVRL1,PRDX3,NR1D2,TBX18,NR4A3,SERPINB5,ITGAV,GPER1,HMGA1,LRRK1,OSR1,SHOX2,CPEB2,SRSF9,JARID2,CCNC,SIGIRR,CASP3,ST13,CRYM,SUDS3,LMCD1,NDRG2,HDAC6,PDGFB,CTNNB1,SIVA1,PSMC2,PASK,MITF,DLG1,DUSP10,CYP1B1,PLK1,THRB,CD55,KCNIP3,CXXC5,TRIM8,ASXL1,ITCH,CBX6,EZR,OPTN,EDNRA,NEIL1,KLF12,PRKCDBP,KLF11,GLA,PSMC1,RUNX2,LMTK3,SERPINE2,UBASH3B,DNAJB2,PDCL,PSMD7,CALM3,SORBS3,HES2,FBLN1,DUSP5,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,FNIP1,MDFIC,PIM1,RFX5,ETV7,PSMA5,MDFI,ELK3,HMG20B,EIF2AK1,RANBP9,CDK5R1,NUDT16,TSC1,PLPP3,NFKBIA,NLRC5,CDAN1,JAK3,TOB1,CTBP1,IFI6,RARG,DRD1,NF2,FOXM1,PSME2,CTDSPL,TP53,P2RX7,OSR2,BAHD1,PATL2,MXD1,SYTL2,PER2,IER3,PDGFA,SAP130,SVBP,SETDB2,BCL6,SMO,TWIST1,NOTCH3,NFKB2,CTDSP2,CHP1,PPIF,SIRT1,TIMP2,BAG4,AKT1,CDC20,ERBB2IP,DUSP4,DAG1,C3orf33,ARHGAP35,SOCS3,HSF4,MYPOP,DNAJC10,IDE,ATP1A1,PTPRJ,RBL1,STAT6,STK38,PSMD3,PEX2,OVOL1,PTBP3,TLE1,CHMP4B,IRF7,CBX4,CTDSP1,ARFGEF3,GLIS3,PINK1,CPEB4,DAP,SERPINB9,PSMD10,AES,NKRF,TRIB2,FZD6,SH2D4A,HDAC9,CD109,IRF2BPL,FOXP2,TAF1B,BMP7,TFAP2A,H2AFY,BRD7,TRIM21,BUB1,KANK2,HEXIM2,MXD3,DUSP1,NFE2L3,HES1,RHOA,PSMB4,WNT10B,IFITM3,PLAUR,GCLC,PPARA,PRICKLE1,RUNX3,COL7A1,FXR2,LEPR,MAPK8IP1,LEMD2,CNOT2,BANK1,SWAP70,SERPINA1,SPINT2,NMI,E2F1,ARRB1,SOX8,NDFIP1,UBE2C,AHR,HIPK3,ZBTB33,PKIA |
| 2.767e-04 | -8.19 | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | 417 | 87 | 17758 | 2588 |
ST13,KLC2,CTDSPL,PPFIBP2,NDC80,TESK2,NUF2,NENF,SNX9,KIAA1147,CALM2,APLP2,SESN3,HSF2,CDKL5,KIF14,SIVA1,CAPG,SRR,FUT1,PIK3CD,CTTN,WBP4,CDKN2D,NEB,SEPHS1,SOAT1,THRB,DOCK4,CD55,DSTN,SAT1,BNIP3L,SP4,HS6ST1,FYN,KLF12,KCNK1,GDE1,PLK2,TBX1,MMP17,WWTR1,KPNA2,HS3ST3B1,TMEM8B,AKNA,CHPT1,NR3C2,KLF2,HSP90B1,CTSB,BIK,PRKAA1,ETV5,ABCG2,NES,PBX3,CALM3,KCNC4,RSAD1,SLC25A36,ZCCHC17,MLPH,FDXR,PAK2,SELK,MAP3K7,GPR161,DNAI1,IFITM3,GUSB,RAPGEF2,CALM1,CRIP2,FBXO9,PLS1,KLHL2,PTPRF,CDKN2AIPNL,ETS2,TMC5,GDF11,ATP1B3,JAK3,SNPH,NGEF |
| 2.768e-04 | -8.19 | positive regulation of cell proliferation | biological process | GO:0008284 | 800 | 155 | 16441 | 2455 |
CNOT8,IL18,CCNB1,PDGFB,LTBP3,EPCAM,CTNNB1,CTGF,IL6ST,IL31RA,DLG1,AKR1B1,ASH2L,ARNT2,SLC39A10,S100A13,CD55,ICMT,SLC25A5,OPTN,PGF,HPSE,AREG,TBX1,NOD2,HDAC1,SP6,TRAF5,CAPN1,GRN,SCN5A,RUNX2,DHPS,HLA-E,SOX9,PRKAA1,ETV5,SLC25A27,FBLN1,BMP2,CALR,C9orf69,RAC2,TNS3,TIMP1,IGF1R,CYR61,PRKCI,MYDGF,NTN1,WNT3A,CALCRL,KIF20B,EPHA1,ILK,EGFR,STX3,NUDT16,INSR,CSF1,OSMR,EGFL7,JAK3,RARG,IL15,FOXM1,SUZ12,ERBB2,COL18A1,CD274,EGR3,BCL2L1,OSR2,PRKACA,EMP2,FLT3,TNFSF9,CD46,PDGFA,CCND1,CCNA2,KIF14,SMO,BCL6,CDKN1B,CDH3,TWIST1,RTKN2,NOTCH3,PDE4D,F2R,SIRT1,AKT1,RIPK2,CDC20,PRKCQ,CD40,FZD7,HSF4,IRS2,PTGS2,WWTR1,STAT1,NRG1,ARNT,LIFR,CTHRC1,NKX3-1,ADGRG1,NES,TGFBR1,ETS1,FGF19,EFNB1,HLA-A,NRP2,PDCD10,IRAK1,PTEN,CST3,PRC1,IGFBP2,IQGAP3,CNOT6L,SYK,S100A6,PDGFC,TGIF1,HES1,ADAM17,WNT10B,HMGN5,NR4A1,ASPM,EIF5A2,CRIP2,UBE2A,CAPNS1,ACVRL1,SCG2,PRDX3,FGFR2,CDCA7L,FGF18,TBX18,NR4A3,E2F1,ITGAV,GPER1,ICOSLG,OSR1,ZMIZ1,SOX8,CD81,SHOX2 |
| 2.778e-04 | -8.19 | membrane part | cellular component | GO:0044425 | 6439 | 1024 | 17570 | 2579 |
GRIK2,SLC25A13,PNPLA2,RET,MCOLN3,TGOLN2,SNX9,CMTM6,SLC35E4,GRM5,LYPD5,NAPG,MUC4,PAQR5,ATP13A3,DNM2,CLDN4,TMEM37,RNF26,TIAM1,CPE,IL10RB,MGAT5,SMIM20,TMEM98,TMEM151A,KDELR3,PRKAR2B,RNF19B,ARF4,LCP1,ENPP1,ATP7B,NOD2,SCN5A,GGA1,SEC61G,ITGA6,COX6C,FAM21C,TTYH3,MARCH8,MEGF8,ATP5H,FLRT3,PANX2,CNGA1,MOXD1,MYLIP,ULBP2,NUP85,PAQR7,PQLC3,ERO1A,GOLT1A,GNA11,SFXN5,IL1R1,CACHD1,SLC4A4,APMAP,RAET1L,DGAT2,CLMN,OSCP1,STK39,TMEM159,RUSC1,TMEM173,DMPK,LFNG,CD82,APOO,RHBDL3,MGST2,MVB12B,REPS1,MUC16,CDH1,XYLT2,ENPP5,DLG3,LRP11,SNX10,TMEM200B,TMCC2,MX1,SNX8,SEC61B,ERMP1,SYP,DNAJB14,TANC1,SNX12,COX20,GABARAPL1,SHROOM3,CORO1C,AXL,WFS1,PNPLA6,PRIMA1,SLC25A30,HSP90B1,FAM189A2,MPZL1,BACE1,TRAF2,SDC4,BIK,FLOT1,BTN3A1,PLPPR4,ZNF219,SLC25A43,SGPL1,SLC25A45,FUT2,IGSF9,ITGB8,TMEM62,MGAT4A,GPC3,FAM20B,BAX,IGFBP2,CASD1,PVRL4,ACBD5,PLSCR1,PIK3R1,MRS2,CNTNAP1,LDLRAP1,PROM1,PLOD2,SYT7,SLC35B3,ITGAV,CD81,WDR45B,TMEM131,BCAM,ILDR1,TNK1,F11R,TEX2,ITPR2,MGAT5B,SPTB,SLC9A3R2,SUSD2,ENTPD4,NUP210,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,SLC44A1,TMEM143,ABCA2,SCARA3,SMAGP,KCNIP3,CELSR2,NFE2L1,CR2,NKAIN1,TMEM164,HS6ST1,TRAM2,KCNMB4,AGPAT2,RRAGD,HS6ST3,PRSS8,LMTK3,LGALS3,FAM234B,RASA2,FXYD3,SLC22A31,ADCK5,NCKAP1,ANO1,B4GALNT1,FRAS1,ICAM5,TBCD,SLC30A6,FCHO1,SELK,TMEM74B,FAR2,CKAP4,PCDH1,RGMB,BTNL9,MGAT4B,EMC2,SCRIB,BCL2L13,NMT2,RASGRP2,FA2H,COL13A1,PHLPP2,SLC2A6,ZDHHC7,PLD1,CDAN1,SMCO4,TMX4,P2RX7,PRR7,EMP2,BCAP31,SYTL2,IER3,ZDHHC23,VAT1,CDH3,TMEM64,NOTCH3,LMAN1,PPIF,CLCN3,PTGER4,DAG1,C3orf33,ATP13A2,PTGS2,TAPBP,PTPRJ,ABHD12,MMP17,MAOA,CHMP4B,EFNA5,SYT13,ST3GAL1,TMEM263,FAM134B,ARFGEF3,BIN1,PINK1,TOR4A,CDH22,CTSB,SCD5,GNAL,MCTP2,LBR,IL22RA1,FZD6,PARM1,VPS26A,DNAJB9,NRP2,M6PR,ZDHHC21,CD109,ALPP,CDK16,UBE2J1,SGK1,IL17RA,CPLX1,TSPAN13,SYK,FAM134C,ATP2B1,LRRC24,GCNT1,P2RX4,RHOA,MOSPD2,PLAUR,TXNDC11,BBS2,DGKE,BCL10,ICOSLG,PTGES,ARHGEF4,GOLGB1,LAMP1,FAM171B,SLC35D2,LGR4,TMEM86B,VANGL1,PJA2,PICK1,SLC9A7,ASPHD2,CYP1A1,STIM1,KCNS3,SERINC2,PIK3CA,SNX16,TACSTD2,MARCH2,ARMCX6,SGCE,ACVR1C,BNIP3L,SLC35C1,POR,RAB2B,GDE1,LRIG1,PPP2R4,SPRY4,F2RL1,SLC31A2,SEMA6B,MRC2,TMEM55B,PRKAA1,TNFRSF19,TSPAN7,C9orf69,CALR,LYPD3,ZNRF2,VASN,ADCK2,TMEM51,TPST1,CACNA1D,SYTL3,GPR161,PIGC,KCNJ12,ADCK3,LPGAT1,CALM1,DCHS1,EPHA1,ATP8B3,ANTXR1,MMP15,SLCO4A1,TJP3,FAAH,ZDHHC20,MPP2,SAMD8,HOOK1,EHD1,MFSD3,SPRED1,GPR107,TCTN2,ST14,ATP2C2,BLCAP,BCL2L1,TMEM170B,TMEM19,DDR1,FLT3,CYP39A1,EPS8L2,CD46,BRI3,PDE4D,EPHB4,TSPAN1,FLOT2,PANK1,UTRN,CLSTN1,TMEM144,ATP1B1,PKMYT1,CBL,B3GALNT2,ITPR3,TRIQK,ALCAM,ATP10D,FZD7,ZMPSTE24,POPDC3,DDOST,FAM210B,TSPAN18,SLC27A3,PRKAR1A,PLSCR4,SLC41A1,EPS8,EFHD2,PLD2,EFNB1,COX7A2,ADGRB2,HLA-A,SLC25A36,TMEM87B,RNF128,FUT8,CD9,DRAM1,ERBB3,SLC16A5,FARP2,B3GNT2,TMEM221,YES1,AIF1L,CPTP,DGCR2,SEC14L4,FGFR2,ABCB1,RYK,ERAP1,FZD5,RGMA,FAF2,UGT8,MAP1LC3B,SLC8B1,HTR1D,EPCAM,CASC4,CDKL5,TRPC1,CTTN,MYRIP,IL1RAP,LAMP3,CERS2,CYP1B1,ACBD3,MAN2A2,GPRC5B,HPSE,KCNK1,MADD,CHPT1,PCSK5,CD99,SERPINE2,BVES,ABCG2,CALM3,TEC,QSOX2,B3GALNT1,NOXA1,OCRL,PRKCI,SUCO,HLA-C,NPTN,C10orf54,SLC12A2,SNX7,PODXL2,SPA17,KIAA1109,STEAP1,C3orf58,MFSD7,INSR,TMEM30A,SH3BP4,CTSA,SHROOM2,TMEM14A,JAK3,RARG,APOL2,SNX30,DRD1,SORBS1,PDIA5,IL27RA,SAYSD1,EXT2,COX14,CYP4F11,REEP1,ECE1,EPB41L4B,EBAG9,SOAT1,PTPRU,C3orf52,TMTC2,CD40,CASP4,SECTM1,SPTBN5,ABCA1,TSPAN15,TGFBR1,SBF1,ITGA2B,XPR1,TMEM63A,A4GALT,RRBP1,ZDHHC13,SLC35A1,B3GALT6,TMEM245,SYBU,FAM73B,LEPR,LEMD2,CD8A,CTSV,SPINT2,FIBCD1,CSGALNACT1,ARRB1,SLC18B1,MCUR1,GRAMD1C,PLOD3,CD33,ABCG1,IL15RA,DNAJC3,CACNA2D2,NRG2,LYNX1,SYTL4,SMIM13,CALM2,ZYX,TGFBR3,AP1M2,PQLC2,CABP1,CYP2S1,RDH14,SLC46A1,FUT1,PIK3CD,ERAP2,VPS11,ICMT,CYP4F3,SLC44A3,WDR11,GRID2IP,DNM1L,RELL1,ARF6,TMTC3,CYP2J2,SLC36A4,ZNRF3,MERTK,FAM189A1,CD22,STT3B,NCAM1,NDUFA12,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,MEST,SPTLC2,CYB5A,PTPRF,SCARB2,SEMA4D,ITPR1,DYSF,OSMR,ALG2,B4GAT1,MAL2,TRPC3,CCDC109B,GALNT12,PKP2,IL13RA1,APC2,PRKACA,KTN1,TNFSF9,CDS1,SCNN1A,LINC00998,ACSL4,RAB27B,TMEM9,SCN3A,ENPP4,FZD4,NRBF2,CYS1,SYNE2,PXYLP1,STX10,SLC9A6,SIPA1L1,TRABD2A,RGS14,TTC8,FARP1,TAOK2,MAN1A2,ANO9,KCNC4,SRPX2,TSPAN17,ICAM1,NEO1,CAPN2,CXCL16,ANK1,SLC27A6,IRAK1,ANKS1B,ALG13,KCNK5,TMBIM6,ADAM15,NPTXR,ITM2C,SGCB,TPCN1,TMX1,S100A6,HCN3,AMOTL2,RAPGEF2,ELOVL3,MFSD2B,EIF5A2,GRIN1,EMP3,SNTB1,TXK,GALNT3,ACVRL1,NUP37,CYBRD1,DCBLD1,UNC93B1,SIGIRR,AGRN,EPHA4,TP53I11,HDAC6,CDIPT,PIGL,SDC1,PDGFB,LMAN2L,TNFRSF18,ANO4,PXMP4,TRAM1,MCTP1,CD55,EZR,ERP44,ESYT1,CLCN2,LHFPL2,PLEKHB1,RHEB,VCP,MFAP3L,WIPI1,DOLPP1,PRKCDBP,PIK3C2B,PIEZO1,TTC9,POMT1,EPB41L4A,HLA-F,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,PGAP1,BMP2,VASP,IGF1R,CMTR2,TMEM8A,ALDH3A2,ABCC1,CHSY3,CYP26B1,SPATA13,ZDHHC3,EPN3,MOSPD3,PVRL2,CSF1,ITGA7,MFSD2A,ATP1B3,TMEM120A,IFI6,NIPA1,KCNAB3,NF2,XYLT1,ERBB2,RASGRP3,SLC7A2,FAM198B,LPIN3,CYP26A1,ATP6V0B,SCN2A,FAR1,GM2A,CPD,TMTC1,EVA1A,DUOX1,RTN4RL1,PRRT4,ATP1A1,PTK7,C1orf43,CNEP1R1,NDST3,POMGNT2,COPG1,CMTM4,PACSIN2,GOLIM4,TM2D2,MFSD14B,TRAPPC10,ADGRG1,CD63,TMEM243,GABRG2,SELL,JAG2,DSE,SIRPA,SLC9A2,MAGEE1,SLC35B4,ABCD1,SLC45A3,CAMK2G,IGDCC4,DLGAP1,MLEC,CRB3,IFITM3,AMFR,CARD19,FNDC3A,NPDC1,MAPK8IP1,CD83,TMEM50B,FAT4,TMC5,PGRMC1,NETO2,TMEM248,PKD2,SPCS3,NDFIP1,FER1L4,SUN1,ACVR1,TMEM41B,ATP8A1,TAP1,PLXNA1,PLA2G16,SLC20A1,RIC1,NCS1,CHST2,IL31RA,STEAP2,ATRNL1,PACSIN1,XKR8,LAMP2,ORAI2,TMEM68,SNTB2,MGAM,GALNT7,SLC17A5,MCFD2,SLC25A5,SPNS3,SGPP1,KDSR,SFXN1,SLC25A4,AREG,GNPTAB,SARAF,TMEM8B,UNC5B,TRAF5,LZTS1,RTN3,DDX58,HLA-E,SLC25A27,NDUFA4,SLC1A3,NOTCH2,PRRG4,KIAA1161,ITGA3,SNX18,SLC16A6,NECAB3,OPN3,SORL1,TNFRSF12A,CD70,CTSD,PIKFYVE,TSPAN33,RIMS2,TMED2,FAM69A,IGSF3,EPB41L5,QSOX1,B3GNT7,PMPCB,FADS2,MMD,MFI2,MICB,ANO6,PTPRH,TMEM133,VEZT,GLT8D2,RASA1,STX3,FAS,GABRD,TMEM54,SLC4A3,PCDH19,EFNA1,MAP3K5,PKD1L2,PLA2G4A,SLC2A4,ARMCX3,TMEM217,TRIP10,IQGAP1,KCTD12,RNF182,CD274,SNN,AIFM2,TMPRSS4,SLC25A35,APLP2,FICD,CNNM4,DAB2IP,TMBIM1,SEC23A,SLC5A11,TMEM43,DMTN,COX11,SLC11A2,PRKCQ,CMTM7,EPHA10,FYN,JAK1,STK26,NRG1,SLC27A1,HS3ST3B1,B4GALT3,NR3C2,DENND5B,SLC16A14,ATP9A,CYB561,GPR180,SLC35G2,TMCC3,SNTA1,PTEN,MGAT1,ATP8B1,SLC44A2,SPRY2,CASK,ERMAP,MPP1,VAMP3,FURIN,C1GALT1C1,NUCB1,RGS9,MAMDC4,CTNS,SLC25A40,GRIN2D,GPER1,SLC25A38,OCLN,ESYT2,CASP3,TMEM184B,EPHX4,DNER,CACNB4,TMC1,KREMEN1,PTCHD4,ABCD4,CHPF,NKAIN3,IMPAD1,TSPAN6,DLG1,SUN3,RP2,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,SYNE3,ROR1,PTGFRN,EDNRA,SEC14L2,ADIPOR1,LEMD1,STARD3NL,ELOVL7,ATP6V1E2,LYSMD4,CA2,LRRN2,KCNN4,FXYD5,NCEH1,KDELR1,GYLTL1B,BTN3A2,EGFR,GLCE,XKRX,GNAS,SLC6A6,PLPP3,PROM2,SLC25A24,IL15,SLC2A8,ABCG4,SLC25A48,ZDHHC12,SMO,STEAP3,RPN2,PDIA6,F2R,HSPA2,SUSD3,KREMEN2,SLC39A8,OSTM1,AP5M1,IGSF8,ERBB2IP,PEX2,CANT1,VSIG10,PLXND1,CYP2U1,REEP4,LIFR,SORT1,CDS2,JKAMP,LRP4,FAM134A,POMGNT1,IL17RB,ADORA1,KIAA0319,IQGAP3,SUN2,SYPL1,ADAM17,LRRC66,MPV17L2,HLA-B,MARC1,ATP6V1C1,GEM,L1CAM,SNPH |
| 2.784e-04 | -8.19 | LOPES_METHYLATED_IN_COLON_CANCER_DN | MSigDB lists | LOPES_METHYLATED_IN_COLON_CANCER_DN | 28 | 12 | 17758 | 2588 |
PITX2,TP73,THRB,CDKN1C,NR3C1,TFAP2A,GATA3,SORBS3,RUNX3,GSTP1,MSH6,DRD1 |
| 2.798e-04 | -8.18 | JAEGER_METASTASIS_DN | MSigDB lists | JAEGER_METASTASIS_DN | 249 | 57 | 17758 | 2588 |
EXPH5,PRSS8,KLK10,GRHL2,NLRX1,ST14,FXYD3,HAL,MCOLN3,DGKA,IRX4,GATA3,SDC1,S100A2,C1orf116,PER2,CDS1,CTNNBIP1,PAK6,AIM1L,SCNN1A,CA2,CDH1,LYPD3,BMP7,AIM1,CDH3,TACSTD2,MAST4,TUBA4A,CYP26B1,SSH3,SMARCA2,ARAP2,ALDH2,CDA,TFAP2C,COL7A1,ITPR3,NFIB,EGFR,DUOX1,BTG1,HLF,ETS2,AREG,FGFR2,MATN2,SPINT2,SERPINB5,KLF5,CTNND1,MAPK13,KLK7,F2RL1,COBL,ARHGEF4 |
| 2.813e-04 | -8.18 | neural tube closure | biological process | GO:0001843 | 87 | 26 | 16441 | 2455 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SDC4,RAB23,PRICKLE1,KIF20B,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,BCL10,TSC1,VASP,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,COBL,RARG,DVL2 |
| 2.817e-04 | -8.17 | GSE3982_DC_VS_TH1_DN | MSigDB lists | GSE3982_DC_VS_TH1_DN | 190 | 46 | 17758 | 2588 |
ANXA3,SPC25,DLGAP5,SDC4,PTTG1,MORC4,KIF2C,KCNC4,IL18R1,MXD1,MYO5C,MAGOHB,WEE1,DNAH6,PASK,ABCA2,BRD7,TWIST1,BUB1,PIK3CD,PDE4D,MAP3K7,DLG3,GFI1,HSPA2,APOBEC3G,HMMR,PRODH,CENPA,SEPT6,PBK,C3orf52,GLO1,EAF2,POLD3,GINS4,SFXN1,CDCA4,SH2D3C,DOLPP1,NFKBIA,SECTM1,AURKA,FAM117A,YOD1,CCNB2 |
| 2.820e-04 | -8.17 | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN | MSigDB lists | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN | 222 | 52 | 17758 | 2588 |
LASP1,PPP1R12A,RALBP1,TSC22D3,INPP5D,RPS6KA1,IQGAP1,CDIPT,LBR,GNB2,CD46,DAPK2,FLII,ADD3,ADRBK1,PLCG2,USP1,PPP1CA,PHKA2,CITED2,FLOT2,CDKN2D,PLCB2,CAMK2G,TUBA4A,MAP3K3,SMARCA2,GCA,AKT1,MAPKAPK3,HTATIP2,ARHGDIB,RASA1,ZMPSTE24,DDX23,RASGRP2,GALNT3,GNAS,JAK1,RCBTB2,PRDX3,PRCP,STAT6,STK38,MAP3K5,ARHGAP4,RGS14,SLC31A2,TOB1,ANXA11,ABCG1,PRKAR1A |
| 2.823e-04 | -8.17 | TPT1 (tumor protein, translationally-controlled 1) | protein interactions | 7178 | 37 | 15 | 16036 | 2547 |
CALR,PLK1,SPP1,ATP1A1,NKX3-1,CALM1,TP53,MSH2,STEAP3,SAMD9,BCL2L1,NOTCH3,HSPB1,EEF1D,PER2 |
| 2.825e-04 | -8.17 | OHGUCHI_LIVER_HNF4A_TARGETS_UP | MSigDB lists | OHGUCHI_LIVER_HNF4A_TARGETS_UP | 44 | 16 | 17758 | 2588 |
SLC2A4,USP18,ELOVL7,EMP2,DDR1,LEPR,CYP39A1,SLC44A3,PROM1,SLC25A4,DRAM1,ABCB1,SLC27A1,RCAN2,PER3,HSPA2 |
| 2.830e-04 | -8.17 | AAGCACA,MIR-218 | MSigDB lists | AAGCACA,MIR-218 | 383 | 81 | 17758 | 2588 |
SPRED1,LGR4,GRIK2,CTDSPL,RET,BAHD1,KCTD9,FANCI,RNF220,RPS6KA2,IMPAD1,PPME1,KLF3,MITF,ZDHHC23,VAT1,ANO4,KCNIP3,FZD4,RNF165,TMEM151A,PRKAR2B,ATP1B1,RNF19B,SOCS3,NFIX,TRIM9,PLCG1,HLF,PPP2R5A,KLF12,DOLPP1,PPP2R4,PPP1CB,HS3ST3B1,SYT13,LIFR,RTN3,CCDC24,LASP1,RUNX2,PARP12,FRMD4A,SH3D19,RAB6A,TTYH3,DUSP5,ZNF212,AKIRIN1,ZFX,UBE2Q2,CA2,FLRT3,RIMS3,PRKG1,SLC12A2,ITM2C,CCDC88A,TMX1,HCN3,TBC1D8B,TACC1,NR3C1,BCL9,PIK3R1,EIF5A2,FBXO8,TRIM35,FAM109A,POLD3,NMT2,GLCE,GALNT3,SERTAD2,CCDC6,FAM3C,DCUN1D1,SFMBT1,ZMIZ1,TOB1,RPS6KA3 |
| 2.839e-04 | -8.17 | upper_aerodigestive_tract-mouth-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma | 6709 | 1055 | 17775 | 2585 |
HECA,GRIK2,AK7,RET,TRAPPC8,LACTB2,SNX9,CARD10,LTBP3,GRM5,NAPG,PHYHIP,PAQR5,ATP13A3,DNM2,PPP1CA,TIAM1,IL10RB,MGAT5,DNAAF3,FBXL16,TMEM151A,TFAP2C,PRKAR2B,ABR,ARF4,LCP1,PIAS3,ENPP1,PLCG1,MPRIP,ATP7B,CELF5,NOD2,HDAC1,TMOD2,ITPKA,STARD13,NXT2,SCN5A,GGA1,ITGA6,MTL5,CCDC64B,RABGGTA,RAC2,FRY,MEGF8,FBXO7,FBXL14,MAP3K9,USP1,ALPK1,PANX2,MAPK7,ZMYM1,DGKG,PPP6R1,KIF20B,ELK1,NPHP3,GOLT1A,SFXN5,GNA11,PLIN5,MAGED2,SLC4A4,ETS2,CLMN,OSCP1,ADAMTS16,DOCK9,TPRN,GRK6,FAM91A1,RCN1,MUC16,ST5,CDH1,XYLT2,RASGEF1A,LRP11,DLG3,ZNF365,MYT1,TMCC2,MX1,SNX8,COL6A2,RIPK2,APOBEC3D,PFKFB2,PTPN9,SEPT6,XRCC6BP1,TANC1,ZNF618,TRIM7,EBF2,GIGYF1,NFIX,CCNB3,SHROOM3,CDK19,CORO1C,WFS1,AXL,PNPLA6,FAM149A,ISOC1,GCAT,ESRP1,TRAF2,OSGIN2,FLOT1,BTN3A1,CTSZ,ZNF219,ZFX,ITGB8,KNDC1,TUBGCP6,KLC3,IGFBP2,RAG1,CASD1,PARP9,PVRL4,ADAMTS2,DUSP23,NUB1,CXorf57,RAB3IP,C4orf27,CNTNAP1,PROM1,LDLRAP1,SYT7,SSNA1,ITGAV,OSR1,CMPK2,ACOT7,PHC1,TLL2,ILDR1,TNK1,BCAM,CNOT8,LMCD1,NDRG2,TEX2,GALM,MGAT5B,SPTB,FANCI,TFAP2E,SUSD2,BTG3,INPP5E,ENTPD4,NUP210,TM9SF2,P4HB,MITF,TMEM143,ABCA2,NTN4,KRT80,KCNIP3,CELSR2,CR2,CKAP2L,NKAIN1,TRIM9,PLEKHG6,KCNMB4,ZNF367,ARRDC1,TC2N,HS6ST3,PRSS8,RUNX2,USH1C,HJURP,SORBS3,FBLN1,TNS3,RINL,FRAS1,ICAM5,TBCD,FCHO1,AHCY,FAR2,WNT3A,NTN1,CKAP4,PCDH1,PLEKHA6,MGAT4B,SCRIB,PDK3,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,SLC2A6,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,USP43,RAD21,HOXB7,TP53,P2RX7,BAHD1,TACC2,LMO4,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,CTDSP2,C3orf33,DAG1,ATP13A2,PTGS2,TAPBP,ZNF628,IDE,ABHD12,RBL1,STK38,ARHGAP4,BTBD6,CTDSP1,PINK1,CDH22,SCD5,GNAL,MCTP2,CDCA8,GDF15,PARM1,SH2D4A,CD109,C16orf74,TFAP2A,GTF2F2,FAM63A,TRIM21,SGK1,SYK,ATP2B1,GCNT1,NFE2L3,FBLN5,MOSPD2,DPP9,MAML2,COL7A1,RNPEP,TXNDC11,USP6,CNOT2,DDAH1,NEIL3,FGF18,ICOSLG,HIPK3,ARHGEF4,GOLGB1,FAM171B,LGR4,HSPG2,TMEM86B,TSC22D3,CUL1,VASH1,OAT,PJA2,ANKS6,STIM1,OSBPL3,SERINC2,PIK3CA,KCNS3,SGCE,SPATA18,ACVR1C,CDYL,SLC35C1,KIF13A,LDB2,POR,MAPK13,FGD1,SEMA6B,RECQL,MRC2,TBC1D1,AKAP17A,TXNDC9,APBA1,PDXDC1,PSIP1,SH3RF2,CALR,DOPEY2,LYPD3,BHLHE41,VASN,DAPK1,PRKG1,ADCK2,CACNA1D,C8orf58,SYTL3,TRAK2,ADCK3,DCHS1,PYGL,WHSC1,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,MATN2,FAM83D,ARAP1,SFMBT1,CABIN1,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,TCF25,REPS2,CAPN12,DLGAP5,ST14,CCDC110,CERCAM,DDIT4L,FAM78A,FLT3,DDR1,CYP39A1,EPS8L2,C11orf84,CCNA2,EPHB4,OSBPL7,SULT2B1,NAGA,DOCK4,COG2,UTRN,KIF1C,TMEM144,PKMYT1,ITPR3,ASB13,ALCAM,FZD7,AMZ2,NGFRAP1,TRIOBP,FAM195A,COBL,DEPDC1,EPS8,HERC5,PLD2,DNAH3,CKAP5,SLC25A36,WWP2,RASSF8,E2F7,FUT8,DRAM1,ERBB3,PDGFC,ALDH2,LONRF3,TCFL5,ZKSCAN2,DIAPH2,FOS,CDK5RAP1,DGCR2,SEC14L4,FGFR2,RIN3,TBX18,ABCB1,WDR62,ESPL1,MELK,RGMA,UGT8,VARS2,COMMD5,ADPRHL1,EPCAM,ZFYVE16,SIPA1L2,CDKL5,CASC4,ARHGEF37,SIVA1,ANKFN1,CEP78,TRPC1,LAP3,ITCH,RGAG1,MAN2A2,GPRC5B,MADD,SP6,GLA,RBM43,ARAP3,ZNF395,SERPINE2,PYROXD2,ETV5,FAM81A,ADAMTSL4,B3GALNT1,CES2,PFKL,OCRL,COL6A1,LIMCH1,BRAT1,NPTN,ZRANB1,ETV7,GAD1,SLC12A2,SNED1,ELK3,VWA1,PDE5A,PRRC1,HEATR5A,MFSD7,RHPN1,SOX13,CTSA,SHROOM2,JAK3,RARG,SNX30,LMO7,NCKAP5,LZTFL1,SORBS1,HDAC11,SOD2,PDIA5,COL18A1,OSR2,PHLDA1,KCTD9,SAP130,ZNF687,CYP4F11,DIXDC1,ZBTB49,EPB41L4B,NFKB2,SOAT1,PTPRU,BTBD19,GLO1,CD40,CASP4,ARHGAP35,HSF4,SPTBN5,ABCA1,KDELC2,ARHGEF11,TSPAN15,ARHGEF7,SH3D19,SHPRH,SBF1,ITGA2B,SYDE2,KIF5B,TOP2A,CARD8,A4GALT,BMP7,RRBP1,CLIP2,SLC35A1,RPGR,MYO5A,B3GALT6,PHF20L1,DCAF6,RC3H2,TTC7A,FAM73B,LEPR,LEMD2,ENDOD1,CD8A,TRIM69,FIBCD1,DTX4,ARRB1,UACA,ZMIZ1,PLOD3,RAB3IL1,NGEF,ACACB,KLK10,TRIM24,ADD1,MRPS15,SMARCAL1,NRG2,DHX8,LGI3,CNTROB,KIF26A,BARD1,CA8,ZYX,RGS12,AP1M2,PQLC2,ARHGAP42,PSMD1,KIAA1107,DNAH6,PPP1R16A,ALDH1A3,RDH14,MANF,PIK3CD,SEMA3G,ERAP2,TUBA4A,SMARCA2,NWD1,SPRTN,MTRF1L,LOXL2,F12,MYOM1,COL12A1,SLC44A3,TRIM47,GRID2IP,WDR11,ANKRD6,LIMK1,MYLK,AGFG2,FAM169A,ALDH6A1,TMTC3,STRN4,SLC36A4,MERTK,LMNA,WDFY1,DNPEP,CD22,PRICKLE4,NCAM1,C9orf72,EPHX1,KIF20A,STAT4,MYBL2,PLS1,SPTLC2,CYB5A,PTPRF,MTFMT,HTT,SETD3,ITPR1,DYSF,OSMR,MDH1,NDE1,DRP2,ZNF502,XDH,ARHGAP11A,PAPSS2,GALNT12,ACTR8,RGS20,ETNK1,TESK2,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SCNN1A,RNF220,DACT1,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,SSH3,CAMSAP3,SYNE2,PLEKHO1,TTC12,SIPA1L1,PLEKHG1,PDXK,RGS14,TTC8,GALK1,NKX3-1,TAOK2,TNRC6C,RBM24,PARP14,PDIA3,ANO9,PKN1,SRPX2,ICAM1,PDIA4,ANK1,IRAK1,ARSG,CTSC,ANKS1B,KCNK5,PLEKHF1,AK3,NPTXR,TPCN1,HCN3,AMOTL2,NUDT8,FAM160A1,RAPGEF2,GRIN1,PLEKHA7,EMP3,SNTB1,ABLIM2,KIAA0141,ACVRL1,ATXN7L3,CENPE,FOXA1,CYBRD1,DCBLD1,FAM199X,GNPDA1,CUL4B,SUDS3,FHDC1,HDAC6,SDC1,LMAN2L,ELF5,TLN2,PXMP4,ANO4,NEB,DDX59,ZNF462,PCGF5,MCTP1,EZR,ESYT1,ANLN,ZBTB7B,CLCN2,VCP,IRX3,DPYSL3,PLCH1,TBC1D17,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,PRKAA2,HLA-F,CNTNAP2,DOCK11,PGAP1,IL18R1,SSX2IP,DAZAP1,VASP,ALDH3A2,C9orf9,ABCC1,CHSY3,CYP26B1,PCBP3,SPATA13,EIF2AK1,ZDHHC3,G2E3,DHDH,EPN3,MFSD2A,ITGA7,LTBP2,CTBP1,RNF146,XYLT1,ERBB2,CCDC68,FAM198B,LPIN3,CYP26A1,PER2,RAD23A,SRPX,PLCG2,GYS1,SCN2A,EGLN3,DVL2,GM2A,CTH,CPD,DUOX1,DNAJC10,ATP1A1,C19orf66,PTK7,ADAMTS14,C1orf43,AIFM3,NDST3,ZNF701,GSDMD,PACSIN2,TM2D2,GNE,CHAC2,DSE,SLC9A2,ABCD1,KLF9,TLE6,IGDCC4,MLEC,AMFR,PPARA,TRIM35,AKAP3,FNDC3A,BCAR1,CD83,BANK1,FAT4,SERPINA1,TWSG1,UBE2C,TBC1D4,SAT2,DIS3L,GAA,ACVR1,PPP4R4,FAM129B,ATP8A1,PPFIBP2,PLXNA1,FAM101B,SLC20A1,CHST2,NCS1,SESN3,ELMO2,PRICKLE3,RGS3,IL31RA,AOX1,ATRNL1,IQCD,MTMR11,PACSIN1,LOC81691,KIFC2,HSPA12A,MGAM,GALNT7,CCNF,SPNS3,ULK2,AHRR,KDSR,SLC25A4,RBM47,GNPTAB,PTER,PLK2,NKD1,FAM110C,EIF4EBP2,UNC5B,TANC2,TRAF5,RTN3,LZTS1,DLAT,INPPL1,HLA-E,CALB2,SLC25A27,NOTCH2,SLC1A3,KIAA1161,CTPS1,SORL1,CD70,CTSD,PIKFYVE,IGSF3,QSOX1,B3GNT7,KIAA1841,MFI2,TBC1D8B,ANO6,PTPRH,AMER1,PKM,KDM3A,FBXO10,RASA1,FRMD4B,DGKH,GABRD,NAB2,SLC4A3,FGD6,PCDH19,MAP3K5,PKD1L2,SLC2A4,ARMCX3,NLRX1,SUZ12,IQGAP1,EGR3,GNB2,APLP2,CYHR1,FICD,DOK4,CDKN1B,PHKA2,NR2C1,TBC1D10B,GPX4,MYO5B,TEP1,AKR1E2,C15orf39,SP4,ZNF469,NIN,EPHA10,OSBPL2,JAK1,STAT1,SLC27A1,KLF5,ZC3H12B,DENND5B,ANKRD13D,SLC16A14,APOBEC3H,CYB561,GPR180,LGALS3BP,FAM111A,C16orf59,OXCT1,MGAT1,PTEN,PRC1,SLC44A2,TAGLN2,CNOT6L,GFI1,TRIM62,OSGIN1,NCOA2,RASGRF1,PCCB,ARAP2,CASK,FURIN,PARP4,LRRC1,RGS9,MAMDC4,CTNS,AMMECR1,SERPINB5,CSTF2,GRIN2D,ETAA1,ARSB,OCLN,USP16,ESYT2,JARID2,EXPH5,LTBP1,KIF2C,TAF6L,KREMEN1,TSEN34,ABCD4,CHPF,ARHGEF10L,LRRC6,CAPG,ANKRD12,POF1B,RAB20,KIF22,MYH14,ARNT2,NFU1,PTPRE,RASGRP1,TDP1,ATL1,SYNE3,FOPNL,ROR1,TCN2,LRRC42,ARHGEF19,TRIM45,IARS2,ADIPOR1,RAP1GAP,MIIP,PPP2R5D,GRN,LRRFIP2,PEX6,ASL,ATP6V1E2,PHLPP1,ZNF432,LRRN2,EBF4,PARD3B,GYLTL1B,HMG20B,MUM1L1,EGFR,GLCE,TSC1,PAPD5,RHOBTB2,ALPK3,KIF12,KLF7,FBXW5,PROM2,GAS2L1,SLC25A24,PSME2,SLC2A8,ZMYND10,PATL2,MICALL2,LRRC45,SLC25A48,SS18,KCTD15,FRYL,ZDHHC12,SMO,STEAP3,SCYL3,FRS3,MAP3K3,TAF5,KREMEN2,IGSF8,ERBB2IP,DUSP4,DOCK5,BFSP1,CANT1,CYP2U1,PLXND1,AKNA,LIFR,CBX4,POC1B,FRMD6,LRP4,FAM134A,TRMT2B,POMGNT1,SNX13,KIAA0319,IQGAP3,RAB3B,ADAM17,ASPM,PHLDB3,NR4A1,LRRC66,OGDHL,MAP1B,KLHL2,SOX8,GEM,L1CAM |
| 2.840e-04 | -8.17 | regulation of phosphoprotein phosphatase activity | biological process | GO:0043666 | 60 | 20 | 16441 | 2455 |
PPP4R4,HSP90B1,PPP1R2,PPP1R12A,NUAK1,CALM1,CALM3,TIPRL,PPP2R3A,CALM2,TSC1,PPP2R5A,HTT,PPME1,PPP2R4,CRY2,SLC39A10,PPP6R1,PPP2R2D,PPP2R5D |
| 2.842e-04 | -8.17 | HECKER_IFNB1_TARGETS | MSigDB lists | HECKER_IFNB1_TARGETS | 89 | 26 | 17758 | 2588 |
DDX58,MYL9,MX1,PARP12,PLSCR1,LAP3,MGAM,HERC5,SAMD9,IFIT3,HERC6,CYP4F3,LGALS3BP,ITGA2B,DTX3L,APOBEC3B,TYMP,STAT1,SH3BGRL2,IRF7,IFIT1,OAS3,CMPK2,IFI6,PARP9,LAMP3 |
| 2.858e-04 | -8.16 | regulation of stress-activated MAPK cascade | biological process | GO:0032872 | 191 | 47 | 16441 | 2455 |
PINK1,TAOK2,GRIK2,FOXM1,TRAF2,EPHA4,PKN1,PHLPP1,GSTP1,FGF19,MECOM,TP73,BMP2,PDCD10,CTGF,IGF1R,DACT1,MAP3K9,DLG1,DUSP10,DAB2IP,MDFIC,MAP3K7,SYK,DVL2,RASGRP1,MDFI,MAP3K3,RIPK2,AKT1,FZD4,ITCH,PBK,EZR,MAP3K6,MAPK8IP1,FZD7,ANKRD6,KIAA1804,MAP3K11,NOD2,FZD5,MAP3K5,F2RL1,GAB1,HIPK3,XDH |
| 2.862e-04 | -8.16 | G2/M Transition | REACTOME pathways | R-HSA-69275 | 115 | 32 | 8202 | 1235 |
CEP70,PPP1R12A,FOXM1,TUBB4B,CUL1,CCNB1,PRKACA,CKAP5,WEE1,CCNA2,CNTRL,CENPJ,CEP78,TUBGCP6,PLK4,NEK2,TUBG1,TUBA4A,PLK1,MYBL2,PRKAR2B,PKMYT1,CDC25C,BORA,CDK1,OPTN,AURKA,PPP1CB,SSNA1,NDE1,CEP41,CCNB2 |
| 2.871e-04 | -8.16 | Signalling to p38 via RIT and RIN | REACTOME pathways | R-HSA-187706 | 232 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 2.871e-04 | -8.16 | ARMS-mediated activation | REACTOME pathways | R-HSA-170984 | 232 | 55 | 8202 | 1235 |
SPRED1,PSME2,IQGAP1,RASA2,PSMD7,PSMD10,ERBB2,NRG2,CALM3,RASGRP3,PSME1,PDGFB,SPTB,FGF19,DUSP5,ITGA2B,CALM2,PDGFA,PSMD1,SHC3,PSMC2,DUSP10,DAB2IP,ERBB3,NCAM1,RASGEF1A,RASGRP1,PSMA5,CAMK2G,FRS3,DUSP1,RASGRF1,PSMB4,RAPGEF2,CALM1,GRIN1,DUSP4,PSMA4,RASA1,EGFR,IRS2,FYN,PPP2R5A,JAK1,FGFR2,PSMD3,FGF18,MAP3K11,ARRB1,GRIN2D,SPTBN5,NRG1,JAK3,PSMC1,PPP2R5D |
| 2.879e-04 | -8.15 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP | 75 | 23 | 17758 | 2588 |
CCNE2,CDKN1C,TUBB4B,HLA-E,MICB,OSR2,TP53I3,TNFSF9,RHOB,GABARAPL1,GNS,BTG1,PCNA,GPRC5B,ACYP1,NAT1,TMBIM6,IFIT1,EFNA1,NPTXR,SHOX2,TOB1,TUBA4A |
| 2.885e-04 | -8.15 | CELLULAR_MACROMOLECULE_METABOLIC_PROCESS | MSigDB lists | CELLULAR_MACROMOLECULE_METABOLIC_PROCESS | 1113 | 203 | 17758 | 2588 |
CASP3,GAA,SIGIRR,TNK1,ACVR1,ST13,AGRN,SSH1,RET,FBXO2,IL18,ISOC2,HDAC6,ERP29,PICK1,DAPK2,CDKL5,P4HB,IL31RA,CAPG,FUT1,DUSP10,RP2,PPP1CA,PTPRE,METAP2,NEK4,PTPN18,MARK1,TNIP1,DSTN,RNF11,MGAM,ERP44,GALNT7,LOXL2,ANLN,ICMT,STK17B,VCP,HS6ST1,MID1IP1,HPSE,DOLPP1,LIMK1,MYLK,PPP2R4,MAP3K11,BMP1,POMT1,ARF6,HSPB1,PCSK5,PRKAA2,CDK17,PEX6,DHPS,DNAJB2,PRKAA1,MERTK,DUSP5,TSPAN7,ATG4A,RABGGTA,B3GALNT1,IGF1R,TIMP1,PAIP2B,NECAB3,RPL39,PAK2,FBXO7,TBCD,PRKCI,PRKG1,TPST1,MAP3K9,DAPK1,STT3B,PIM1,GAD1,MYLIP,CCDC88A,NAGPA,PIGC,DDB2,QSOX1,UFD1L,PTPRH,MGAT4B,STRADB,EIF2AK1,ILK,NUBP1,EGFR,RASA1,NMT2,GLCE,STK17A,MAPKAPK2,MMP15,TSC1,INSR,FNTA,AURKA,ALG2,JAK3,CTBP1,DMPK,NF2,ST14,HDAC11,PDIA5,ERBB2,TESK2,MAPK4,ZFYVE9,EPM2A,CCND1,PPME1,PLK4,RPN2,PHKA2,LMAN1,PDIA6,LOXL1,F2R,ATG4D,SEPHS1,MAP3K3,SIRT1,CDKN2AIP,BAG4,AKT1,COG2,PTPRU,PTPN9,CDC20,COX11,DUSP4,CBL,MAP3K6,CASP4,ZMPSTE24,PTPRJ,IDE,STK38,KIAA1804,STAT1,NRG1,HS3ST3B1,RPL22,MAPK12,WASF3,PINK1,DYRK3,MAN1A2,CTSB,BACE1,CTSZ,TGFBR1,FBXO6,POMGNT1,PKN1,SBF1,TRIB2,AIP,PPP2R3A,WWP2,FUT2,PTEN,CDK16,CENPJ,MGAT4A,FUT8,RRBP1,SGK3,SGK1,WWP1,ERBB3,SLC35A1,GCNT1,AMFR,PARP4,FURIN,UBE2A,YES1,PRDX4,TXK,BCL10,CASP7,ACVRL1,PLOD2,UBE2D2,NR4A3,CSGALNACT1,ERAP1,HMGA1,PLOD3,UBE2C,CD81,HIPK3,ABCG1 |
| 2.895e-04 | -8.15 | coagulation | biological process | GO:0050817 | 527 | 108 | 16441 | 2455 |
PLA2G4A,MYL9,KIF3C,PAPSS2,INPP5D,KLC2,TP53,DGKA,GATA3,F11R,ITPR2,KIF2C,PRKACA,KIF26A,PDGFB,PDGFA,CALM2,WEE1,STIM1,CYP4F11,PLCG2,PIK3CA,IRF2,KIF22,LMAN1,F2R,RASGRP1,TUBA4A,LAMP2,ENPP4,SOD1,AKT1,PRKAR2B,PRKCQ,F12,ATP1B1,CD40,ITPR3,MYL12A,PLCG1,FYN,KCNMB4,ABHD12,AXL,HDAC1,HSPB1,F2RL1,MAFF,PRKAR1A,SERPINE2,CD63,ITGA6,DGKQ,HABP4,SELL,KIF23,CALM3,RACGAP1,DOCK11,FBLN1,MERTK,ITGA2B,FZD6,SIRPA,RAC2,ITGA3,TIMP1,GATA2,CD9,PRKG1,AK3,WNT3A,DGKG,SYK,ATP2B1,RHOA,PLSCR1,PLAUR,CALM1,ANO6,PIK3R1,HMG20B,C1GALT1C1,PDE5A,YES1,ILK,BCAR1,KIF11,GNA11,RHOB,DGKE,PDE11A,RASGRP2,DGKH,GNAS,SERPINA1,PRCP,ITPR1,ARRB1,CENPE,ITGAV,ATP1B3,CBX5,TRPC3,L1CAM,DOCK9,IRF1,EHD1 |
| 2.902e-04 | -8.14 | Kinesin_motor_dom | interpro domains | IPR001752 | 44 | 16 | 18293 | 2672 |
KIF3C,KIFC2,KIF20A,KIF1C,KIF23,KIF20B,KIF13A,KIF2C,KIF11,KIF26A,KIF5B,KIF13B,KIF14,KIF22,CENPE,KIF12 |
| 2.908e-04 | -8.14 | positive regulation of cellular component biogenesis | biological process | GO:0044089 | 369 | 80 | 16441 | 2455 |
NF2,AGRN,TP53,P2RX7,HDAC6,SNX9,SDC1,MNS1,EPS8L2,CTNNB1,CTGF,RALB,PSMC2,MITF,CAPG,DLG1,PLK4,DNM2,CDKN1B,ESPN,TWIST1,CTTN,PSRC1,BAG4,VPS4B,CLSTN1,PRKCQ,LDB2,DAG1,VCP,LCP1,DPYSL3,PTPRJ,IDE,BHLHB9,LIMK1,EFNA5,PIEZO1,ARF6,F2RL1,PSMC1,COBL,PINK1,BMF,SOX9,SDC4,BIK,FLOT1,SORBS3,TGFBR1,NCKAP1,SRPX2,ICAM1,ADGRB2,RAC2,VASP,BMP7,FLRT3,TUBGCP6,GTF2F2,BAX,FNIP1,SLAIN2,CNOT6L,EPB41L5,RHOA,WNT10B,FMN1,PIP4K2C,RGCC,EPHA1,FAS,CNOT2,TSC1,SWAP70,HTT,ARAP1,ARPC2,COL16A1,AHR |
| 2.918e-04 | -8.14 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN | 185 | 45 | 17758 | 2588 |
CCNI,GALNT12,TSC22D3,ARHGEF7,MTL5,ASL,DGKA,EGR3,KCNC4,CA8,KBTBD11,DENND2D,SIRPA,ATG4A,VASP,CARD8,CTGF,FRY,MITF,BCL6,SGK1,FAM102A,PDE4D,TIAM1,MAST4,SPRY2,CTDSP2,TUBA4A,ING1,ELK3,FBLN5,CENPA,LPGAT1,PIP4K2C,ERP44,POR,RHEB,GABARAPL1,PLCH1,CD8A,WDR19,RHOBTB2,CABIN1,MAPK13,EGLN1 |
| 2.918e-04 | -8.14 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 185 | 45 | 17758 | 2588 |
GCLM,SLC35D2,TXN,IL15RA,LGALS3,S100A11,CD63,CAST,IQGAP1,TMX4,PTTG1,EFHD2,CBLL1,DUSP5,BTG3,TYMP,CTSC,PFKL,RGS3,OSBPL3,CAPG,MDFIC,PPP1CA,TMEM64,FAR2,PDIA6,MYBL1,PPIF,CASK,C6orf1,S100A4,ALCAM,NPDC1,SPAG1,FAS,FRMD4B,NOD2,NETO2,EIF4EBP2,CTSA,PIEZO1,MAP3K5,TTC39C,AHR,CPPED1 |
| 2.918e-04 | -8.14 | GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP | 185 | 45 | 17758 | 2588 |
GAS2L1,GAA,LFNG,CIT,SOX9,ERCC6L,FLOT1,PRSS22,HMGN3,PLXNA1,BCAP31,SSX2IP,PCNA,PSMD1,PIK3AP1,SLC16A6,KIF14,TMEM143,AK3,STT3B,SPRY2,TTLL1,DUSP1,GCNT1,MOSPD2,LONRF3,B9D2,PAPD7,TEP1,VPS4B,CBX6,KCTD20,CCBL2,TRIM35,EIF2AK1,RAD17,SPNS3,GINS4,VCP,OPTN,RND3,BHLHB9,TDRD7,PLXND1,SRSF9 |
| 2.920e-04 | -8.14 | DASU_IL6_SIGNALING_UP | MSigDB lists | DASU_IL6_SIGNALING_UP | 57 | 19 | 17758 | 2588 |
NAGPA,AGRN,HLA-F,SOD2,TFAP2C,SORBS3,IER3,TAPBP,IRAK1,ZFP36,FCHO1,COL6A1,DNM2,GEM,PTGES,MAFF,COL16A1,ATP2B1,CKS2 |
| 2.920e-04 | -8.14 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | 57 | 19 | 17758 | 2588 |
CASP3,PQLC3,ITGA6,RASA1,PDGFA,CCND1,SPP1,SERPINA1,AREG,KCNN4,FUT8,WWTR1,CAPG,CD9,FXYD5,SSNA1,ACOT7,CSRP2,NGEF |
| 2.950e-04 | -8.13 | TRAYNOR_RETT_SYNDROM_UP | MSigDB lists | TRAYNOR_RETT_SYNDROM_UP | 40 | 15 | 17758 | 2588 |
PLA2G4A,LTBP1,CALD1,STAT1,FNIP1,PRICKLE1,RNF182,NTN4,MOXD1,SNTB1,FBLN1,TNFRSF19,ANKRD29,SYTL2,IRX3 |
| 2.950e-04 | -8.13 | PID_FOXM1_PATHWAY | MSigDB lists | PID_FOXM1_PATHWAY | 40 | 15 | 17758 | 2588 |
CCND1,PLK1,ONECUT1,RB1,CENPA,CCNA2,FOXM1,ETV5,NEK2,CKS1B,AURKB,CCNB1,CCNB2,FOS,CDK1 |
| 2.961e-04 | -8.12 | ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP | MSigDB lists | ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP | 32 | 13 | 17758 | 2588 |
FUCA1,RB1,APLP2,TIMP2,PRCP,S100A4,ITGA6,CST3,SPINT2,NUCB2,SEPP1,TIAM1,TCN2 |
| 2.974e-04 | -8.12 | MICROTUBULE_ORGANIZING_CENTER | MSigDB lists | MICROTUBULE_ORGANIZING_CENTER | 66 | 21 | 17758 | 2588 |
PLK1,PCGF5,DLGAP5,UXT,KIF20B,CNTROB,SAC3D1,CKAP5,NIN,TOP2A,CNTRL,TUBGCP6,MAP3K11,ABCA2,NEK2,TUBG1,PKD2,BUB1,NDE1,CEP41,ESPL1 |
| 2.974e-04 | -8.12 | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | 66 | 21 | 17758 | 2588 |
GFPT1,CASP3,SORT1,TIMP2,AVPI1,HSP90B1,NR4A1,NDRG1,F12,DUSP5,DNAJB9,PDIA4,APOBEC3B,AGPAT2,UAP1,ZFP36,UBE2J1,TNFRSF12A,ITPKA,HSPB1,TRAM1 |
| 2.974e-04 | -8.12 | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | MSigDB lists | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 66 | 21 | 17758 | 2588 |
HMMR,KLF2,NR4A1,SAT1,FOS,EPCAM,TIMP3,ATP1A1,CA2,CDH1,CTGF,PLK2,ZFP36,FOSB,ITPR1,BCL6,SERPINB5,SGK1,CTNND1,TIAM1,DUSP1 |
| 3.005e-04 | -8.11 | ST_ADRENERGIC | MSigDB lists | ST_ADRENERGIC | 36 | 14 | 17758 | 2588 |
PITX2,AKT1,ITPR1,PIK3R1,PIK3CA,ASAH1,PIK3CD,ITPR2,PHKA2,ITPKA,ITPR3,GNA11,DAG1,EGFR |
| 3.005e-04 | -8.11 | ONGUSAHA_TP53_TARGETS | MSigDB lists | ONGUSAHA_TP53_TARGETS | 36 | 14 | 17758 | 2588 |
NQO1,PQLC3,SERPINE2,FXYD3,SAT1,TAP1,TP53,DGKA,COL18A1,TNFRSF18,TOB1,CSRP2,EPHX1,FAS |
| 3.006e-04 | -8.11 | HSP90AA1 (heat shock protein 90kDa alpha (cytosolic), class A member 1) | protein interactions | 3320 | 760 | 156 | 16036 | 2547 |
TNK1,TRIM2,ST13,EPAS1,CAMKK1,CUL4B,RET,EPHA4,CUL1,NANS,HDAC6,SPSB1,PAK6,TYMP,PSMD1,RPS6KA2,P4HB,PASK,KCNS3,TUBG1,IRF2,CERS2,NLRP4,ACVR1C,AGO4,AURKB,SLC25A5,RNF19B,CDK1,VCP,PI4K2B,LIMK1,TRAF3IP1,MAP3K11,IARS2,HSPB1,STARD13,NR2C2,PRKAA2,UBASH3B,PRKAA1,HERC6,MERTK,SH3RF2,FLII,IGF1R,DAPK1,MAP3K9,FBXL14,PRKCI,FNIP1,ALPK1,PIM1,MAPK7,HP1BP3,TESK1,CALM1,SCRIB,EIF2AK1,EPHA1,PKM,ILK,PDIK1L,UNC45B,FBXO10,EGFR,CDK5R1,G2E3,MAGED2,DCUN1D1,RHOBTB2,AURKA,MDH1,CDK18,ALG2,MAP3K5,FBXO27,RPS6KA3,FBXW5,RAD21,IRF1,DMPK,SLC2A4,TCF25,FOXM1,TUBB4B,RPS6KA1,NDRG1,RALBP1,TP53,ERBB2,TESK2,MAPK4,GRK6,PCBP1,DDR1,FLT3,PRKACA,CDK14,CDH1,BCL6,ZBTB49,IFIT1,LMAN1,HSPA2,CKS2,SIRT1,MAP3K3,BAG4,AKT1,PRKCQ,CDC25C,MAP3K6,TRIM7,FYN,JAK1,DDOST,AXL,STK38,AREL1,NR3C2,ARNT,PINK1,KLHL13,PSMD10,TGFBR1,FBXO6,PKN1,AIP,LGALS3BP,MTRNR2L1,FOXP2,CEP97,IRAK1,ADRBK1,CALD1,SGK3,CKS1B,SGK1,WWP1,ERBB3,MAP3K7,RAG1,CAMK2G,HES1,NR3C1,PPARA,FBXO9,PIM3,YES1,ACVRL1,RCBTB2,DTX4,ARRB1,HMGA1,AHR |
| 3.012e-04 | -8.11 | Inositol phosphate metabolism | KEGG pathways | hsa00562 | 71 | 23 | 6908 | 1076 |
MTM1,INPPL1,ALDH6A1,INPP5D,PIP4K2C,ISYNA1,CDIPT,PLCH1,PI4K2B,PLCG1,INPP5E,PTEN,OCRL,IMPAD1,PLCG2,PIK3CA,INPP4B,PIK3C2B,PIK3CD,MINPP1,PIKFYVE,ITPKA,PLCB2 |
| 3.012e-04 | -8.11 | Inositol phosphate metabolism | KEGG pathways | ko00562 | 71 | 23 | 6908 | 1076 |
MTM1,INPPL1,ALDH6A1,INPP5D,PIP4K2C,ISYNA1,CDIPT,INPP5E,PI4K2B,PLCH1,PLCG1,PTEN,IMPAD1,OCRL,PLCG2,INPP4B,PIK3CA,PIK3C2B,PIK3CD,MINPP1,ITPKA,PIKFYVE,PLCB2 |
| 3.017e-04 | -8.11 | hydrolase activity | molecular function | GO:0016787 | 2416 | 416 | 16491 | 2452 |
GAA,KLK10,SSH1,TMEM86B,ATP8A1,PNPLA2,KLC2,HEXB,TAP1,SMARCAL1,CCNO,DHX8,LACTB2,PLA2G16,SEPT4,DPP8,KIF26A,PICK1,HELZ2,PSMD1,DNAH6,PALD1,ATP13A3,DNM2,TUBG1,TINAGL1,PPP1CA,CPE,APOBEC3G,ERAP2,METAP2,TUBA4A,SMARCA2,LOC81691,KIFC2,TNIP1,CASP9,CDA,MGAM,KIF13A,PIF1,F12,PNKD,POR,RAB2B,GINS4,ARF4,SGPP1,ENPP1,PLCG1,GDE1,DNM1L,ATP7B,PTER,PPP2R4,BMP1,HDAC1,RNASEL,ARF6,DDX58,RECQL,INPPL1,MRPL44,ALDH6A1,TMEM55B,RAB23,KIF23,KIAA1161,ATG4A,GNS,RAC2,DNPEP,ATP5H,PPP4R1,PCYOX1,MSH2,USP38,USP1,CTSD,PIKFYVE,EPHX1,DNAI1,NAGPA,UFD1L,PMPCB,KLK5,KIF20A,PRSS23,PTPRH,KIF20B,ATP8B3,MEST,DPYSL4,GOLT1A,PSMA4,GNA11,RHOB,DCP2,PDE11A,DHX32,PTPRF,MMP15,NT5C2,NAAA,FAAH,APMAP,AGBL5,KLK7,IFIH1,ADAMTS16,PLA2G4A,MTM1,KIF3C,DLGAP5,CAPN12,TUBB4B,ST14,RALBP1,INPP5D,RHBDL3,ATP2C2,PRSS22,NUDT12,ART5,GNB2,TMPRSS4,ZFYVE9,APPBP2,EPM2A,CD46,APOBEC3B,RALB,ENPP5,RNASEH2A,PDE4D,LGMN,ARL4D,RAB27B,NAGA,ATG4D,MYO5B,MX1,ENPP4,SSH3,ERMP1,APOBEC3D,CAPN6,PFKFB2,PTPN9,VPS4B,KIF1C,PXYLP1,RAD17,RAB38,ATP1B1,XRCC6BP1,ATP10D,ZMPSTE24,AMZ2,ACYP1,ACAD10,HAGHL,INPP4B,PNPLA6,PPP1CB,TRABD2A,RAB29,ZC3H12B,GEN1,OTUD5,NUDT6,ATP9A,MAN1A2,BACE1,ARL4C,PDIA3,APOBEC3H,CTSZ,PLD2,PLPPR4,DNAH3,IFT27,PNPLA5,RND1,CAPN2,DIRAS3,GNB5,PTEN,CTSC,ARSG,TMEM62,ALG13,KLC3,ADAM15,ATP8B1,ERCC2,RAG1,CNOT6L,MSH6,ADAMTS2,OPLAH,NUDT8,LONRF3,DUSP23,FURIN,DBR1,ARSK,KIF11,GPLD1,PLA2G15,ABCB1,PPM1H,ERAP1,CENPE,HMGA1,ARSB,ESPL1,ACOT7,USP16,TLL2,CASP3,PPM1J,GNPDA1,ABHD17B,CNOT8,EPHX4,SUDS3,PHOSPHO1,VARS2,KIF2C,HDAC6,PIGL,TSEN34,ABCD4,ADPRHL1,RAB15,INPP5E,PCNA,ENTPD4,P4HB,DPYSL2,IMPAD1,ARL1,DDHD2,PAPL,PSMC2,DLG1,ABCA2,DUSP10,KIF22,RAB20,MYH14,PTPRE,DDX59,ATL1,TDP1,PTPN18,LAP3,USP18,C12orf65,KLK6,ARHGDIB,ARFRP1,TYSND1,RHEB,VCP,DPYSL3,EDNRA,MAN2A2,PLCH1,NEIL1,HPSE,DOLPP1,IARS2,GLA,RAP1GAP,PSMC1,PPP2R5D,CAPN1,CPPED1,PCSK5,RRAGD,PRSS8,PEX6,UBASH3B,ABCG2,ATP6V1E2,ASAH1,RAB6A,PHLPP1,ADAMTSL4,DUSP5,PGAP1,MYO5C,OTUD1,CA2,CES2,KIF13B,OCRL,SRP54,AHCY,NCEH1,ZRANB1,PLCB2,DESI2,PSMA5,ABCC1,DPYSL5,USP31,PDE5A,AMDHD1,GNAS,NUDT16,PHLPP2,OTUD6B,PLPP3,RAB31,CTSA,YOD1,PLD1,ATP1B3,KIF12,USP43,DYNLRB1,HDAC11,CTDSPL,ABCG4,MRAS,LPIN3,ATP6V0B,KIF14,PPME1,PLCG2,GLB1L2,ECE1,MINPP1,CTDSP2,GM2A,SULF2,CPD,SIRT1,GCA,FIGNL1,PTPRU,DUSP4,CDC25C,CASP4,ATP13A2,TAPBP,PTPRJ,IDE,ATP1A1,PAFAH1B3,ABHD12,MMP17,ADAMTS14,CANT1,XRCC3,LTA4H,NDST3,ABCA1,CTDSP1,MAN2B2,SHPRH,CTSB,GNAL,GNE,ERCC6L,ERI2,NOTUM,NTAN1,SBF1,HDAC9,TOP2A,KIF5B,ADORA1,ALPP,GALNS,GTF2F2,ABCD1,MYO5A,ATP2B1,CAMK2G,FAH,DUSP1,ADAM17,RHOA,RAB3B,PSMB4,CFAP46,GUSB,DPP9,CAPNS1,GGH,RNPEP,SPAG1,SCRN2,USP6,DDX23,CNOT2,ENDOD1,CTSL,FUCA1,DDAH1,CASP7,RND3,PRCP,NEIL3,CTSV,OTUB2,GLB1,SPCS3,GEM,ATP6V1C1,ABCG1,DIS3L |
| 3.018e-04 | -8.11 | GSE3982_MAST_CELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_BASOPHIL_DN | 180 | 44 | 17758 | 2588 |
ZNF395,EPAS1,GRIK2,DNAJC3,ARL4C,OSGIN2,AKAP17A,APBA1,PJA2,CA8,MAP1LC3B,HLA-A,ZFYVE16,ADD3,TRANK1,UBE2J1,BRD7,PDE4D,ULBP2,CTDSP2,SMC4,DUSP1,ARAP2,PCDH1,FBLN5,ADCK3,LGALS8,FOXJ2,UTRN,ARHGDIB,ATP10D,BCAR3,SFXN1,TMEM164,PPP2R5A,JAK1,ETS2,KBTBD2,UBE2D2,RAB31,CCDC69,USF2,CTBP1,PTGES |
| 3.018e-04 | -8.11 | GSE3982_BASOPHIL_VS_TH2_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH2_UP | 180 | 44 | 17758 | 2588 |
DDX58,EPAS1,CD63,TRIM5,NDRG1,TSC22D3,OSGIN2,C6orf106,AKAP17A,RASGRP3,DSE,FLT3,SIRPA,ZFYVE16,ADD3,TRANK1,SHC3,BCL6,DRAM1,WWP1,PTPRE,CLIP2,SOCS5,ARAP2,MBP,TCEB2,PARP4,MGAM,CR2,SPTLC2,ATP10D,CASP4,RHEB,PIAS3,GALNT3,TSC1,JAK1,PPP2R5A,CDK19,SLC4A3,TDRD7,CHPT1,MYL12B,CD33 |
| 3.025e-04 | -8.10 | SMIRNOV_RESPONSE_TO_IR_6HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_UP | 154 | 39 | 17758 | 2588 |
FAM169A,RAB23,GDF15,DSE,SDC1,DDR1,GNB2,PGAP1,TNFSF9,LMNA,FZD6,SAC3D1,RABGGTA,IER3,APOBEC3B,FAM46A,CES2,METTL7A,FDXR,DRAM1,ACTA2,TAX1BP3,CD70,F2R,MYBL1,LAMP3,DDB2,ADCK3,FHL2,SESN1,RNF19B,CYP4F3,TP53I3,FAS,PGF,FUCA1,CSF1,PLK2,TOB1 |
| 3.026e-04 | -8.10 | V$FOXO1_02 | MSigDB lists | V$FOXO1_02 | 228 | 53 | 17758 | 2588 |
CDKN1C,CHCHD7,THRA,NDRG1,TSC22D3,PNPLA2,ETV5,IRX4,SEPP1,DHRS3,SH2D4A,BMP2,FOXP2,TFAP4,PDGFA,CD109,ST5,FRY,ITGB8,IL6ST,LMO4,MITF,DIXDC1,TSPAN13,KLF9,NTN1,CLIP2,CAMK2G,STK35,TRIM8,KIF20A,ASXL1,SERTAD4,NUB1,CLSTN1,TCF7,ROR1,NFIB,NFIX,GNAS,MDK,PITX2,TBC1D17,KLF12,PELI2,NRG1,EIF4EBP2,LEMD1,C1orf43,LIFR,MAFF,RAD21,EHD1 |
| 3.038e-04 | -8.10 | skin-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-squamous_cell_carcinoma | 506 | 102 | 17775 | 2585 |
KIAA1462,TRIM24,NF2,NQO1,EPHA4,RET,TP53,GATA3,ERBB2,CAMK1D,CCNL1,FLT3,DDR1,FAM46C,STIL,EXT2,FANCI,TP73,CCND1,WEE1,CTNNB1,CDH1,IL6ST,MITF,SMO,BCL6,PIK3CA,CDKN1B,NOTCH3,EPHB4,MYH14,TFG,TIAM1,ETV4,SZRD1,SMARCA2,RIPK2,AKT1,ASXL1,ERBB2IP,AURKB,CBL,IDH1,FANCE,KDSR,FYN,JAK1,AXL,INPP4B,TRAF5,ARNT,LIFR,PRKAR1A,TAOK2,TRAF2,ESRP1,ETV5,ABCG2,NOTCH2,PSIP1,BMP2K,SIX4,HLA-A,NRP2,RB1,IGF1R,PTEN,GPC3,SGK3,PRKCI,MAP3K9,ATP8B1,SGK1,BUB1,ERCC2,ERBB3,HLA-C,PIM1,MAP3K7,SYK,MSH6,DDB2,PDGFC,AMER1,PIK3R1,MAML2,FOXL1,EGFR,FAS,GNAS,TSC1,HLA-B,HTT,FGFR2,CCDC6,NFKBIA,ABCB1,AURKA,MAP3K5,JAK3,AFAP1,FOXA1 |
| 3.063e-04 | -8.09 | TARTE_PLASMA_CELL_VS_PLASMABLAST_DN | MSigDB lists | TARTE_PLASMA_CELL_VS_PLASMABLAST_DN | 305 | 67 | 17758 | 2588 |
ACVR1,TXN,ADD1,DLGAP5,FOXM1,PSME2,IQGAP1,SOD2,KIF2C,CCNB1,OAT,STIL,PCNA,CCNA2,KIF14,ATP13A3,PLK4,TUBG1,TAX1BP3,KIF22,TUBA4A,CKS2,PPIF,CLCN3,CENPA,CDC20,ARHGDIB,CCNF,CDK1,PRIM1,KPNA2,RECQL,GCLM,PPP1R2,SELL,KIF23,NKRF,COX6C,LBR,TOP2A,RB1,AIM1,PAK2,NEK2,CKS1B,SGK1,ACTA2,AHCY,OSTF1,CD70,MYO5A,PSMA5,HMMR,UFD1L,MAPKAPK3,GGH,KIF11,FAS,GALNT3,DBI,PRPS2,CENPE,ATP1B3,CBX5,UBE2C,ESPL1,ACOT7 |
| 3.083e-04 | -8.08 | Deregulation of Rab and Rab Effector Genes in Bladder Cancer | WikiPathways | WP2291 | 16 | 9 | 4455 | 729 |
EXPH5,GCC2,MLPH,MADD,SYTL4,RAB27B,MYRIP,SYTL3,SYTL2 |
| 3.083e-04 | -8.08 | VERHAAK_AML_WITH_NPM1_MUTATED_DN | MSigDB lists | VERHAAK_AML_WITH_NPM1_MUTATED_DN | 239 | 55 | 17758 | 2588 |
SERPINE2,HSPG2,ATP9A,ITGA6,XYLT1,EPS8,CACNA2D2,GMPR,GATA3,BAIAP3,GPSM2,DSE,TRIB2,DHRS3,TSPAN7,FZD6,MECOM,RPS6KA2,DPYSL2,LMO4,SORL1,MDFIC,TSPAN13,TACSTD2,MTMR11,NCAM1,ITM2C,SMAGP,MX1,PRODH,ARAP2,ALDH2,DCHS1,PTGER4,EZR,AK4,RUNX3,MEST,LHFPL2,OPTN,ENDOD1,BANK1,PROM1,H1F0,ABCB1,SH3BP4,CSGALNACT1,EGFL7,ADIPOR1,PLXND1,FHL1,TRAF5,HSPB1,F2RL1,RRAGD |
| 3.083e-04 | -8.08 | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | 239 | 55 | 17758 | 2588 |
SLC25A24,RUNX2,ARMCX3,TTC39B,ELOVL7,ARL4C,RHPN2,HMGN3,RASGRP3,IL13RA1,PLA2G16,SEPP1,DHRS3,FAM46C,IL18R1,EPCAM,B3GALNT1,TNS3,IGF1R,RNF128,ARSG,OSBPL3,CD9,MDFIC,CTTN,TIAM1,F2R,PTPRE,CPE,SLC16A5,FARP2,GCA,PLSCR1,IFITM3,STAT4,OXR1,MGAM,KDELR3,PYGL,GGH,PRKCQ,EAF2,FOS,ALCAM,CASP4,RHOB,ENPP1,WIPI1,P4HA2,ARFGAP3,GRAMD1C,PLIN3,HOOK1,F2RL1,XDH |
| 3.093e-04 | -8.08 | glycogen metabolic process | biological process | GO:0005977 | 56 | 19 | 16441 | 2455 |
GAA,PGM1,PPP1R2,UGP2,AKT1,CALM1,CALM3,PYGL,EPM2A,PER2,CALM2,PRKAG2,IL6ST,PGM2L1,PPP1CB,GYS1,PPP1CA,PHKA2,PHKG2 |
| 3.094e-04 | -8.08 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | 762 | 145 | 17775 | 2585 |
LTBP1,TNK1,ADD1,SSH1,HSPG2,AASS,FAM129B,RET,FHDC1,GATA3,VARS2,SPTB,EPDR1,CDKN2C,PAK6,CTNNB1,ALDH1A3,FOSB,KCNS3,PIK3CA,DNM2,ABCA2,SUN3,ARNT2,PIK3CD,NEB,ERAP2,ASXL1,IDH1,COL12A1,DPYSL3,PIK3C2B,SPRY4,ZNRF3,NOTCH2,TFAP4,FLII,TNS3,RB1,IGF1R,GATA2,FRAS1,MSH2,ALPK1,PIM1,MOXD1,PLCB2,GPR161,GCC2,WDR72,AMER1,PTPRH,MYBL2,WHSC1,TCF7,KIF20B,UNC45B,EGFR,PRX,IL1R1,SCARB2,NCOA3,NT5C2,UAP1,CDCA5,NLRC5,FGD6,CLMN,OSMR,SEMA3A,JAK3,AFAP1,ADAMTS16,WDR63,RAD21,PKD1L2,SPRED1,NF2,REPS2,GRHL2,NLRX1,SUZ12,APOO,TP53,WDTC1,ERBB2,COL18A1,FLT3,C1orf116,PER2,SAP130,TACC2,PLCG2,EPB41L4B,RNASEH2A,NOTCH3,CAMSAP3,AKT1,DRAP1,PTPN9,CBL,SNAPC2,SOCS3,PRDM11,IRS2,JAK1,SHROOM3,AXL,TLE1,NRG1,RPL22,DENND5B,ANKRD13D,PARP14,ARHGEF11,ATP9A,HABP4,ANO9,JAG2,SBF1,SEPP1,SRPX2,CKAP5,PTEN,FUT8,CLIP2,GFI1,SPRY2,MSH6,HCN3,FAH,SUN2,HES1,PDGFC,RASGRF1,ZWINT,RAPGEF2,PIK3R1,MRS2,COL7A1,FAM109A,MAP1B,NR1D2,FGFR2,UACA |
| 3.094e-04 | -8.08 | acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_T_cell_leukaemia | 762 | 145 | 17775 | 2585 |
LTBP1,TNK1,ADD1,SSH1,HSPG2,AASS,FAM129B,RET,FHDC1,GATA3,VARS2,SPTB,EPDR1,CDKN2C,PAK6,CTNNB1,ALDH1A3,FOSB,KCNS3,PIK3CA,DNM2,ABCA2,SUN3,ARNT2,PIK3CD,NEB,ERAP2,ASXL1,IDH1,COL12A1,DPYSL3,PIK3C2B,SPRY4,ZNRF3,NOTCH2,TFAP4,FLII,TNS3,RB1,IGF1R,GATA2,FRAS1,MSH2,ALPK1,PIM1,MOXD1,PLCB2,GPR161,GCC2,WDR72,AMER1,PTPRH,MYBL2,WHSC1,TCF7,KIF20B,UNC45B,EGFR,PRX,IL1R1,SCARB2,NCOA3,NT5C2,UAP1,CDCA5,NLRC5,FGD6,CLMN,OSMR,SEMA3A,JAK3,AFAP1,ADAMTS16,WDR63,RAD21,PKD1L2,SPRED1,NF2,REPS2,GRHL2,NLRX1,SUZ12,APOO,TP53,WDTC1,ERBB2,COL18A1,FLT3,C1orf116,PER2,SAP130,TACC2,PLCG2,EPB41L4B,RNASEH2A,NOTCH3,CAMSAP3,AKT1,DRAP1,PTPN9,CBL,SNAPC2,SOCS3,PRDM11,IRS2,JAK1,SHROOM3,AXL,TLE1,NRG1,RPL22,DENND5B,ANKRD13D,PARP14,ARHGEF11,ATP9A,HABP4,ANO9,JAG2,SBF1,SEPP1,SRPX2,CKAP5,PTEN,FUT8,CLIP2,GFI1,SPRY2,MSH6,HCN3,FAH,SUN2,HES1,PDGFC,RASGRF1,ZWINT,RAPGEF2,PIK3R1,MRS2,COL7A1,FAM109A,MAP1B,NR1D2,FGFR2,UACA |
| 3.102e-04 | -8.08 | TPR_REGION | prosite domains | PS50293 | 124 | 34 | 11866 | 1802 |
TTC8,ST13,CEP70,TMTC3,DNAJC3,KLC2,ERCC6L,WDTC1,GPSM2,AIP,APPBP2,TTC21B,NOXA1,TRANK1,FICD,KLC3,IFIT1,TMTC1,LONRF3,TTC7A,EMC2,TANC1,NPHP3,IFIT3,TMTC2,UNC45B,SPAG1,RGPD5,PEX5,TTC12,P4HA2,CABIN1,TTC9,TANC2 |
| 3.116e-04 | -8.07 | GSE29618_BCELL_VS_PDC_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_UP | 175 | 43 | 17758 | 2588 |
KLF2,PARP12,CKAP2,HLA-F,TSC22D3,PPFIBP2,RASGRP3,TRIB2,FAM46C,BMP2K,CHST2,CDK14,FAM111A,SP100,CD22,PLCG2,CDKN1B,ECE1,PIKFYVE,ATP2B1,TRAK2,DUSP1,TUBA4A,SYPL1,HES1,CD55,MMD,EZR,ARHGDIB,RHOB,CD83,KLHL2,IRS2,BTG1,SWAP70,BANK1,NFKBIA,RYK,NR4A2,PIK3C2B,TTC9,TRAF5,KLF7 |
| 3.135e-04 | -8.07 | mesenchymal cell development | biological process | GO:0014031 | 121 | 33 | 16441 | 2455 |
SEMA6B,ACVR1,RET,SOX9,TGFBR1,FAM101B,EFNB1,FGF19,GBX2,BMP2,TGFBR3,CTNNB1,BMP7,SMO,ADAM15,TWIST1,SEMA3G,SEMA3B,EPB41L5,HES1,S100A4,LOXL2,EDNRA,PITX2,SEMA4D,FGFR2,CORO1C,TBX1,FAM83D,NRG1,EFNA1,SOX8,SEMA3A |
| 3.138e-04 | -8.07 | STK33_DN | MSigDB lists | STK33_DN | 261 | 59 | 17758 | 2588 |
MFSD3,ANXA3,CAST,GALNT12,RET,ASL,PDGFRL,ZNRF3,PM20D2,KBTBD11,CA8,FLT3,FAM46C,RSAD1,BEX2,NEO1,SYDE2,C16orf74,SPIN4,MGAT4A,FDXR,AIM1,PCYOX1,TMEM143,ZDHHC23,ACOX2,FAM84B,C12orf75,RASGRP1,LAMP3,PCCB,HN1L,DCHS1,OGDHL,CDA,CR2,PLS1,PRKAR2B,CYFIP2,ALCAM,FANCE,SPNS3,CYP4F3,ARHGEF26,ENDOD1,PLCH1,DDAH1,MPRIP,MATN2,KIAA1804,PPM1H,KLF5,PLXND1,TANC2,NDFIP1,CHPT1,CXorf56,FAM134B,NXT2 |
| 3.140e-04 | -8.07 | V$E4F1_Q6 | MSigDB lists | V$E4F1_Q6 | 272 | 61 | 17758 | 2588 |
CCNI,CCDC24,LTBP1,MRC2,TSC22D3,SOX9,HABP4,RAB6A,GRK6,EGR3,MORF4L2,HDAC6,CHPF,IRF2BPL,AKIRIN1,CXCL16,ZNF687,CYR61,ANKS1B,SHC3,CALD1,DACT1,FLRT3,FOSB,PLK4,TRPC1,CRY2,TSPAN13,RFX5,ARL4D,ARMCX6,RBMS2,WBP5,DUSP1,ZNF462,NR3C1,NR4A1,CALCRL,KDELR3,PELI3,FXR2,BCL2L13,TP53INP2,ATP10D,FZD7,ARF4,PITX2,GNAS,COQ10A,PDLIM3,SCG2,ZNF367,C1orf21,NR4A3,NR4A2,GEM,OSR1,MAFF,FOXA1,RPS6KA3,RUSC1 |
| 3.142e-04 | -8.07 | haemangioma | COSMIC cancer mutations | haemangioma | 21 | 10 | 17775 | 2585 |
GNAS,TSC1,PLCG1,CTNNB1,AKT1,PTEN,MSH2,PIK3CA,TP53,IDH1 |
| 3.187e-04 | -8.05 | CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I | MSigDB lists | CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I | 373 | 79 | 17758 | 2588 |
SLC35D2,SLC25A24,KLK10,SSH1,LGR4,CERCAM,EGR3,BCL2L1,SNN,SLC20A1,PDGFB,MXD1,C11orf84,RAB15,RALB,OSBPL3,SNX16,CRY2,RASGRP1,XKR8,CPD,FZD4,PTPRU,ACVR1C,C15orf39,CCNF,CBL,PNKD,ULK2,IRS2,PLEKHG6,GNPTAB,NKD1,LRIG1,TSPAN18,PLXND1,PDPR,NXT2,SCN5A,CDH22,SLC16A14,KLHL13,GNAL,SLC25A27,PBX3,EFHD2,TGFBR1,TEAD3,FRAS1,MGAT4A,FNIP1,ADAM15,USP38,FAM84B,C8orf58,KLF9,ATP2B1,MDFI,IGDCC4,DIAPH2,NPHP3,FNDC3A,STX3,USP6,SOX13,TSC1,NCOA3,CTNS,SLC4A4,SYT7,PLA2G15,PGM2L1,PCDH19,OSMR,YOD1,HMGA1,CPEB2,RPS6KA3,NIPA1 |
| 3.196e-04 | -8.05 | GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN | 191 | 46 | 17758 | 2588 |
ANXA3,ATP9A,SDC4,NDC80,CDCA8,FLOT1,PHLDA1,UHRF1BP1L,IER3,APOBEC3B,ATP6V0B,MSH2,AKR1B1,CKS1B,BUB1,AHCY,RNASEH2A,PDE4D,ALDH3A2,SCN3A,FAH,CKS2,PPIF,NFE2L3,TIMP2,HN1L,LAP3,PBK,PLAUR,GGH,KIF20B,PDK3,DUSP4,GTF2A2,KIF11,CDK1,STEAP1,RHOB,VCP,RAB11FIP1,NUP37,NCAPG2,SERPINB1,IFI6,ACOT7,DLAT |
| 3.196e-04 | -8.05 | GSE13229_MATURE_VS_INTMATURE_NKCELL_DN | MSigDB lists | GSE13229_MATURE_VS_INTMATURE_NKCELL_DN | 191 | 46 | 17758 | 2588 |
ARHGEF3,FAM160B1,POC1B,PTTG1,ASB9,PDCL,C5orf30,C6orf106,HDGFRP2,COX6C,PHF1,TSEN34,CDK14,CAPN2,SS18,NAPG,PHYHIP,MDM1,ST5,SNX18,FAM20C,PCYOX1,TRIM3,ZNF692,USP1,GFI1,MYLIP,TMED2,ATL1,ACBD3,AMFR,CASP9,MGAM,KBTBD8,UBAC1,ARSK,NDRG3,TIMP3,CASP7,ACYP1,PPM1H,ITGAV,ZBTB33,RPS6KA3,RAD21,PRKAR1A |
| 3.208e-04 | -8.04 | THIOREDOXIN_1 | prosite domains | PS00194 | 17 | 9 | 11866 | 1802 |
DNAJC10,TXN,P4HB,TMX4,PDIA5,PDIA3,PDIA6,TMX1,PDIA4 |
| 3.211e-04 | -8.04 | extrinsic component of membrane | cellular component | GO:0019898 | 254 | 58 | 17570 | 2579 |
TNK1,FARP1,PACSIN2,NF2,SERPINE2,ST14,IQGAP1,GNAL,RACGAP1,TEC,SYTL4,SNX9,APC2,MAP1LC3B,SYTL2,MUC16,CDH1,CTNNB1,CDK16,SNX18,PIK3CA,SNX16,PIK3CD,EPB41L4B,TIAM1,MYLIP,SNX10,SYK,SYTL3,S100A6,SNX7,FARP2,EPB41L5,SNX8,NRBF2,PLAUR,PIK3R1,EZR,YES1,GNA11,SNX12,NMT2,GABARAPL1,TXK,GNAS,EPN3,RGS9,NUCB1,FYN,JAK1,WIPI1,ARRB1,PIK3C2B,EPB41L4A,WDR45B,JAK3,SNX30,ESYT2 |
| 3.215e-04 | -8.04 | nuclear division | biological process | GO:0000280 | 460 | 96 | 16441 | 2455 |
SUN1,SPC25,DLGAP5,LFNG,SLC2A8,ACTR8,PTTG1,NDC80,XIAP,NUF2,TDRKH,KIF2C,CCNB1,SNX9,CENPN,WEE1,CCNA2,SETDB2,KIF14,KIF22,HSPA2,CKS2,PLK1,NEK4,PSRC1,PBK,CDC20,VPS4B,CDCA2,NUSAP1,PKMYT1,AURKB,CCNF,ANLN,CDC25C,CDK1,TRIOBP,CHMP4B,XRCC3,RGS14,SGOL1,REEP4,PPP2R2D,ZC3HC1,PRKAR1A,PPP1R12A,KLHL13,CIT,EPS8,CDCA3,ERCC6L,CDCA8,KIF23,RACGAP1,SPDL1,CKAP5,SAC3D1,TOP2A,RB1,SNX18,PTEN,TUBGCP6,NEK2,MSH2,BUB1,KNTC1,MSH6,SMC4,CYP26B1,REC8,RHOA,ZWINT,CENPC,PAPD7,ASPM,MYBL2,KIF20B,SKA1,BORA,KIF11,FAM64A,PAPD5,CDCA5,FAM83D,AURKA,CENPE,GEM,NDE1,NUP37,NCAPG2,CCNB2,UBE2C,ESPL1,USP16,FBXW5,RAD21 |
| 3.221e-04 | -8.04 | BOYLAN_MULTIPLE_MYELOMA_C_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_DN | 53 | 18 | 17758 | 2588 |
SOAT1,AK7,SAT1,KIF13A,TANC1,DOCK5,C3orf33,FZD6,IRS2,SPP1,PLOD2,KCNN4,ABCB1,RAB20,PDE4D,EGLN3,SERPINB1,KLF7 |
| 3.225e-04 | -8.04 | PID_P53_DOWNSTREAM_PATHWAY | MSigDB lists | PID_P53_DOWNSTREAM_PATHWAY | 134 | 35 | 17758 | 2588 |
PPM1J,NDRG1,CD82,TAP1,TP53,COL18A1,GDF15,BCL2L1,CCNB1,AIFM2,S100A2,DUSP5,TP73,RB1,SPP1,PCNA,PTEN,FDXR,BAX,BCL6,MSH2,STEAP3,CTSD,DUSP1,DDB2,BNIP3L,SESN1,TP53I3,EGFR,FAS,HTT,TADA2B,E2F1,SERPINB5,FOXA1 |
| 3.237e-04 | -8.04 | Sema4D induced cell migration and growth-cone collapse | REACTOME pathways | R-HSA-416572 | 24 | 11 | 8202 | 1235 |
MYL9,RAC2,RHOA,ARHGEF11,SEMA4D,LIMK1,ERBB2,MYH14,MYL12B,RHOB,RND1 |
| 3.239e-04 | -8.03 | maintenance of location | biological process | GO:0051235 | 136 | 36 | 16441 | 2455 |
SUN1,LTBP1,GAA,PINK1,HSP90B1,NFKBIE,THRA,PNPLA2,HEXB,PDIA3,PSMD10,FTH1,B4GALNT1,CALR,SORL1,SUN3,TLN2,GM2A,MDFI,KDELR1,SOAT1,SUN2,AKT1,SYNE3,ACVR1C,ASPM,SYNE2,EZR,KDELR3,DAG1,PLIN5,ENPP1,ATP7B,NFKBIA,DGAT2,PKD2 |
| 3.246e-04 | -8.03 | regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070302 | 192 | 47 | 16441 | 2455 |
PINK1,TAOK2,GRIK2,FOXM1,TRAF2,EPHA4,PKN1,PHLPP1,GSTP1,FGF19,MECOM,TP73,BMP2,PDCD10,CTGF,IGF1R,DACT1,MAP3K9,DLG1,DUSP10,DAB2IP,MDFIC,MAP3K7,SYK,DVL2,RASGRP1,MDFI,MAP3K3,RIPK2,AKT1,FZD4,ITCH,PBK,EZR,MAP3K6,MAPK8IP1,FZD7,ANKRD6,KIAA1804,MAP3K11,NOD2,FZD5,MAP3K5,F2RL1,GAB1,HIPK3,XDH |
| 3.260e-04 | -8.03 | Endosomal/Vacuolar pathway | REACTOME pathways | R-HSA-1236977 | 11 | 7 | 8202 | 1235 |
CTSL,HLA-B,HLA-C,HLA-E,HLA-F,CTSV,HLA-A |
| 3.262e-04 | -8.03 | GTPASE_REGULATOR_ACTIVITY | MSigDB lists | GTPASE_REGULATOR_ACTIVITY | 124 | 33 | 17758 | 2588 |
ARHGEF3,FARP1,ARAP3,ARHGEF11,IQGAP1,RALBP1,RASA2,RGS20,ARFGEF1,RASGRP3,RACGAP1,ARHGEF10L,RGS12,RGS3,RANBP1,RGS5,TIAM1,FARP2,DOCK4,RAPGEF2,ARHGDIB,ABR,RASA1,RGS9,RCBTB2,MADD,ARAP1,ARFGAP3,FGD6,ARHGAP4,RGS14,RAP1GAP,FGD1 |
| 3.285e-04 | -8.02 | carbohydrate derivative biosynthetic process | biological process | GO:1901137 | 656 | 130 | 16441 | 2455 |
SLC35D2,ACACB,UGT8,AGRN,HSPG2,SLC25A13,NANS,MGAT5B,SDC1,PIGL,CHST2,CHPF,TYMP,MUC4,PAPSS1,FUT1,TFG,TIPARP,MGAT5,TNIP1,CDA,SLC17A5,GALNT7,MCFD2,ARF4,VCP,MAN2A2,HS6ST1,AREG,DOLPP1,GNPTAB,POMT1,HS6ST3,B4GALT4,ADAMTSL4,PGAP1,B4GALNT1,CALR,B3GALNT1,ATP5H,CTPS1,STT3B,PPP6R1,TMED2,TRAK2,PIGC,CHSY3,GFPT1,NAGPA,B3GNT7,PQLC3,MGAT4B,GYLTL1B,CALCRL,PYGL,GLCE,GNAS,PRKAG2,UAP1,DCK,PRPS2,CTSA,ALG2,B4GAT1,SLC2A4,UGP2,PAPSS2,GALNT12,XYLT1,PHLDA1,EXT2,ART5,MUC16,XYLT2,RPN2,LMAN1,SIRT1,SEC23A,RFK,PANK1,PXYLP1,B3GALNT2,DDOST,CANT1,SLC27A1,HS3ST3B1,B4GALT3,ST3GAL1,NDST3,POMGNT2,CMAS,TRAPPC10,MAN1A2,SDC4,GNE,PDIA3,CTSZ,POMGNT1,DSE,FUT2,MGAT1,CTSC,ALG13,MGAT4A,GPC3,A4GALT,FUT8,UBE2J1,AK3,SLC35A1,GCNT1,B3GALT6,SHMT1,B3GNT2,MLEC,PLSCR1,PLAUR,PARP4,AK4,C1GALT1C1,COL7A1,FOXL1,FUCA1,GALNT3,SERPINA1,SLC35B3,CSGALNACT1,GLB1,CMPK2,ACOT7 |
| 3.286e-04 | -8.02 | positive regulation of developmental process | biological process | GO:0051094 | 1108 | 206 | 16441 | 2455 |
ACACB,ACVR1,AGRN,LGR4,EPHA4,RET,CACNA2D2,GATA3,MORF4L2,CAMK1D,CCNB1,PDGFB,LTBP3,GRM5,TP73,CTNNB1,CTGF,NPNT,CDKL5,IL6ST,DDHD2,DNM2,TACSTD2,PACSIN1,TIAM1,RASGRP1,CYP1B1,ITCH,EZR,LOXL2,SAV1,POR,RHEB,IRX3,DPYSL3,PLCG1,GPRC5B,HPSE,DNM1L,LIMK1,TBX1,BMP1,ITPKA,HSPB1,GRN,RUNX2,SERPINE2,LGALS3,SOX9,ETV5,PRKAA1,LMNA,MECOM,CORO1B,BMP2,CALR,RB1,ITGA3,CA2,CYR61,FAM20C,GATA2,MEGF8,FLRT3,PRKCI,SUCO,TNFRSF12A,NPTN,MYDGF,C10orf54,NTN1,WNT3A,RIMS2,SOCS5,EPB41L5,MMD,ANO6,WHSC1,HMG20B,PDE5A,PLS1,KIF20B,EPHA1,ILK,RHOB,GNAS,NCOA3,INSR,HTT,SEMA4D,SETD3,CSF1,TMEM30A,AURKA,ARPC2,MAP3K5,SEMA3A,RPS6KA3,EHD1,FOXO6,NF2,HOXB7,IL15,THRA,INPP5D,RPS6KA1,P2RX7,OSR2,EGR3,MNS1,TNFSF9,CD46,PDGFA,CCND1,DACT1,BCL6,SMO,DAB2IP,TWIST1,TMEM64,SIRT1,TIMP2,RIPK2,AKT1,DMTN,CDC20,CLSTN1,CD40,DAG1,ARHGAP35,SOCS3,HSF4,PTGS2,FYN,BHLHB9,AXL,STAT6,PTK7,CORO1C,WWTR1,TRIOBP,KLF5,EFNA5,NRG1,RGS14,ARNT,COBL,MAPK12,BIN1,WASF3,ANXA3,CTHRC1,PINK1,ARHGEF7,FLOT1,GDF15,CRABP2,ETS1,SRPX2,TEAD3,SIX4,ADGRB2,HDAC9,NEO1,CTNNBIP1,BMP7,TFAP2A,BAX,H2AFY,MAPK11,CITED2,RAG1,IQGAP3,GFI1,SYK,FAM134C,TLE6,MSH6,HES1,TGIF1,RHOA,WNT10B,ASPM,RAPGEF2,RGCC,FOS,BBS2,MAP1B,CD83,BTG1,DDAH1,PROM1,FGFR2,ACVRL1,TBX18,FGF18,ERAP1,PPP2R3C,GPER1,HMGA1,OSR1,SOX8,ARSB,SHOX2,L1CAM,FOXA1 |
| 3.288e-04 | -8.02 | MODULE_241 | MSigDB lists | MODULE_241 | 71 | 22 | 17758 | 2588 |
MYL9,P2RX4,WASF3,TRIP10,FOXM1,SOD2,GDF15,ATP1B1,ETS1,LGALS3BP,IER3,MGAT1,SEMA4D,SECTM1,MYLK,DNM2,RAB31,TAX1BP3,NRG1,PDXK,PIEZO1,LGMN |
| 3.288e-04 | -8.02 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | 71 | 22 | 17758 | 2588 |
TGIF1,ARHGEF3,CD55,PRSS23,CDKN1C,CRIP2,SDC4,ARL4C,PKP2,IFIT3,TNFRSF19,SP4,EPCAM,BTG1,PPP2R5A,CTGF,CAPG,ABCB1,SLC27A1,TACSTD2,EFNA1,IFIH1 |
| 3.288e-04 | -8.02 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | MSigDB lists | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | 71 | 22 | 17758 | 2588 |
MRC2,SEC61B,PSMB4,SEC61G,PSME2,HLA-F,TAP1,PSMD7,PDIA3,PSMD10,PSME1,PSMA4,HLA-A,CALR,HLA-B,PSMD1,PSMD3,PSMC2,ITGAV,HLA-C,PSMC1,PSMA5 |
| 3.290e-04 | -8.02 | MODULE_138 | MSigDB lists | MODULE_138 | 85 | 25 | 17758 | 2588 |
MYL9,P2RX4,WASF3,COL9A3,IL15RA,MAPKAPK3,FXYD3,CASP9,DHX8,KLK6,GDF15,PRKCQ,EGR3,ETS1,ZNF212,ARHGAP35,ST5,KIAA0141,DGCR2,BMP7,MYLK,NRG1,DRP2,TOB1,MYO5A |
| 3.290e-04 | -8.02 | M_PHASE_OF_MITOTIC_CELL_CYCLE | MSigDB lists | M_PHASE_OF_MITOTIC_CELL_CYCLE | 85 | 25 | 17758 | 2588 |
PLK1,ZWINT,DLGAP5,CIT,NDC80,NUSAP1,KIF2C,RAD17,PKMYT1,ANLN,CDC25C,KIF11,NPM2,CCNA2,CDCA5,NEK2,AURKA,KIF22,BUB1,KNTC1,CENPE,UBE2C,MPHOSPH9,ESPL1,SMC4 |
| 3.307e-04 | -8.01 | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | MSigDB lists | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | 165 | 41 | 17758 | 2588 |
CAST,EPHA4,ERBB2,COL18A1,IL18,TGFBR1,JAG2,NOTCH2,PDGFB,EFNB1,NRP2,FZD6,CALR,PDGFA,SPP1,TIMP1,PTEN,CYR61,IL6ST,F2R,TIMP2,WNT10B,FZD4,PLAUR,CALCRL,EPHA1,FZD7,EPHA10,PGF,BTG1,PTGS2,PROM1,TIMP3,HPSE,FGFR2,SERPINB5,OSMR,ERAP1,EGFL7,EFNA1,ITGAV |
| 3.309e-04 | -8.01 | regulation of phosphatidylinositol 3-kinase signaling | biological process | GO:0014066 | 74 | 23 | 16441 | 2455 |
NKX3-1,SERPINE2,SOX9,ERBB2,CBL,PDGFB,FLT3,C3orf58,PDGFA,FYN,SEMA4D,PTEN,PIK3AP1,DAB2IP,NRG1,TWIST1,GPER1,MYDGF,ERBB3,UNC5B,F2RL1,F2R,RASGRP1 |
| 3.315e-04 | -8.01 | GSE14000_UNSTIM_VS_16H_LPS_DC_DN | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_DN | 186 | 45 | 17758 | 2588 |
PARP12,IL15,ARHGEF11,TRIP10,GMPR,UBE2Z,FTH1,PSME1,CD274,C11orf95,PRRG4,DTX3L,SS18,BTG3,DRAM1,TPST1,TRIM21,IRF2,ECE1,PIM1,CKAP4,PARP9,RIPK2,KIAA0040,COQ10B,MICB,NUB1,NFE2L1,RUNX3,PIM3,PI4K2B,CASP7,PHLPP2,NFKBIA,TDRD7,AGFG2,NFKBIZ,IRF7,CMPK2,JAK3,SLC31A2,IFIH1,APOL2,WDR63,NXT2 |
| 3.315e-04 | -8.01 | RAF_UP.V1_DN | MSigDB lists | RAF_UP.V1_DN | 186 | 45 | 17758 | 2588 |
WASF3,COL9A3,TSC22D3,CALB2,SOX9,PDGFRL,EGR3,SLC7A2,OSR2,SYTL2,CCND1,B3GALNT1,BTG3,IGF1R,AIM1,TFAP2A,IGFBP2,ARNT2,EPB41L4B,MINPP1,MYBL1,CPE,BTBD3,RASGRP1,CASK,CELSR2,CTNNAL1,SLC39A8,OSTM1,MICB,LPGAT1,SH3BGRL,AK4,PLS1,PDK3,ALCAM,FOS,MDK,RND3,CCDC6,PLK2,LRIG1,MYLK,INPP4B,SHROOM2 |
| 3.315e-04 | -8.01 | GSE3982_DC_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_DN | 186 | 45 | 17758 | 2588 |
PLEKHG3,ANXA3,ARAP3,REPS2,MPZL1,MCTP2,SNN,KCNC4,PRR7,IL18R1,TRANK1,PTEN,RALB,KLF3,DLG3,CDKN2D,SYK,CTDSP2,CKAP4,EEF1D,TUBA4A,RHOA,FOXJ2,SYNE2,PYGL,SRSF5,SPTLC2,RNF19B,STK17B,CYP4F3,STX3,ARHGAP35,MFAP3L,PPP2R5A,ETS2,JAK1,ACAD10,SH2D3C,NMI,CSGALNACT1,ZNF165,FAM117A,ALPK3,CANT1,IRF7 |
| 3.315e-04 | -8.01 | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN | 186 | 45 | 17758 | 2588 |
ANXA3,ARAP3,TXN,S100A11,CD63,SOD2,FLOT1,EFHD2,ARHGEF40,TSEN34,IER3,VASP,CTSC,RALB,PPP4R1,SORL1,IFIT1,ECE1,TMBIM1,S100A6,CKAP4,XKR8,LAMP2,GCA,NRBF2,IFITM3,MAPKAPK3,LITAF,PYGL,IFIT3,CASP4,STX3,FAS,PTGS2,PPP2R5A,SERPINA1,SEMA4D,PRDX3,NMI,SECTM1,RAB31,SLC31A2,RTN3,IFI6,CPPED1 |
| 3.315e-04 | -8.01 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN | 186 | 45 | 17758 | 2588 |
EXPH5,CDS2,LRRFIP2,IGFBP6,HLA-F,APOO,FTH1,MNS1,ECI1,HDAC9,RCN1,DOPEY2,RPS6KA2,PHF7,RNF128,RALB,RGS3,LMO4,TAGLN2,CTTN,S100A13,CKAP4,DOCK4,CPD,TGIF1,VPS11,TIMP2,ALDH2,TMEM43,B9D2,KIAA0040,LAP3,SAT1,DCHS1,NFE2L1,SAV1,IFIT3,DAG1,C18orf8,TRIM9,INSR,ADIPOR1,NRG1,SERPINI1,ATP1B3 |
| 3.330e-04 | -8.01 | TRPC3 (transient receptor potential cation channel, subfamily C, member 3) | protein interactions | 7222 | 23 | 11 | 16036 | 2547 |
MX1,PLCG1,CALM1,ITPR1,PRKG1,TRPC1,ITPR3,TRPC3,PLCB2,GNA11,STX3 |
| 3.338e-04 | -8.01 | actin filament bundle organization | biological process | GO:0061572 | 52 | 18 | 16441 | 2455 |
SORBS1,RHOA,USH1C,HSP90B1,ADD1,DMTN,EPS8,EZR,FAM101B,LCP1,CORO1B,DPYSL3,ZYX,SWAP70,PDCD10,ARRB1,ESPN,SHROOM2 |
| 3.342e-04 | -8.00 | FXYD1 (FXYD domain containing ion transport regulator 1) | protein interactions | 5348 | 8 | 6 | 16036 | 2547 |
ATP1A1,ATP1B1,PPP1CA,PRKACA,PTTG1,DMPK |
| 3.342e-04 | -8.00 | CD151 (CD151 molecule (Raph blood group)) | protein interactions | 977 | 8 | 6 | 16036 | 2547 |
CD46,GRAMD1C,ITGA3,PTGFRN,CD82,ITGA6 |
| 3.386e-04 | -7.99 | Corticotropin-releasing hormone | WikiPathways | WP2355 | 90 | 28 | 4455 | 729 |
PRKAA2,CASP3,RHOA,AKT1,NR4A1,CASP9,PRKCQ,IL18,GRK6,ELK1,FOS,ADRBK2,GNB2,GNA11,GNAS,PLCG1,GNB5,CTNNB1,PLCG2,NFKBIA,FOSB,TFAP2A,PRKCI,ARRB1,NR4A2,ECE1,MAP3K5,NCOA2 |
| 3.392e-04 | -7.99 | MODULE_60 | MSigDB lists | MODULE_60 | 408 | 85 | 17758 | 2588 |
MYL9,GAA,BCAM,HSPG2,EPAS1,S100A11,CRYM,THRA,TAP1,GMPR,TP53I11,ITPR2,PLA2G16,ECI1,SPTB,CARD10,ARHGEF16,CHPF,IER3,CCND1,ZYX,TYMP,ST5,SRPX,TRANK1,TACC2,RGS3,DNM2,GOT1,ECE1,NOTCH3,LGMN,SMAGP,COL6A2,S100A4,CDA,ARFRP1,PKMYT1,ICMT,MYOM1,AGPAT2,TBX1,WFS1,PIK3C2B,PLXND1,PDXK,PPP2R5D,ABCA1,GRN,PCOLCE,FAM189A2,IGFBP6,BLVRB,PKN1,DHRS3,TSPAN7,M6PR,RAC2,LLGL2,NECAB3,BDH1,COL6A1,FDXR,IGFBP2,CITED2,EPHX1,QSOX1,MAPKAPK3,NR4A1,FHL2,EMP3,TCF7,DPYSL4,CDK5R1,RHOB,CD8A,TIMP3,KIAA0141,PVRL2,DHRS2,ITGA7,SLC4A3,CDK18,TMEM159,JAK3 |
| 3.398e-04 | -7.99 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | 160 | 40 | 17758 | 2588 |
KLF2,MRC2,TRAPPC10,TSC22D3,HAL,COL4A5,TGOLN2,PLA2G16,MAP1LC3B,FLT3,TIMP1,ZFP36,FOSB,SORL1,CITED2,GFI1,MYLIP,TRAM1,PTPRE,SPRY2,NCOA2,DUSP1,TCFL5,RNF11,ATP1B1,ZFAND5,ALCAM,FOS,STK17B,IRS2,CD8A,BTG1,NFKBIA,SIPA1L1,NR4A2,NDE1,SLC31A2,ABCA1,TMEM131,CD33 |
| 3.411e-04 | -7.98 | response to decreased oxygen levels | biological process | GO:0036293 | 272 | 62 | 16441 | 2455 |
CASP3,PINK1,NKX3-1,SLC2A4,HSP90B1,CPEB4,EPAS1,SLC2A8,NDRG1,PRKAA1,TP53,ITPR2,CCNB1,PDGFB,ETS1,ICAM1,PICK1,LMNA,BMP2,CAPN2,CYP1A1,TGFBR3,ADORA1,CTGF,IRAK1,P4HB,PTEN,BMP7,VASN,CST3,CDKN1B,AHCY,TWIST1,ERCC2,ARNT2,CITED2,EGLN3,HP1BP3,SIRT1,ADAM17,RHOA,AKT1,TCEB2,PPARA,RGCC,PRKCQ,SLC11A2,LOXL2,ATP1B1,PDK3,SOCS3,EDNRA,PTGS2,PLOD2,ITPR1,E2F1,UBE2D2,NR4A2,CPEB2,ARNT,DRD1,EGLN1 |
| 3.420e-04 | -7.98 | central_nervous_system-frontal_lobe-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-oligoastrocytoma_Grade_III | 6 | 5 | 17775 | 2585 |
CDKN2C,IDH1,PTEN,EGFR,TP53 |
| 3.434e-04 | -7.98 | GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN | 181 | 44 | 17758 | 2588 |
DDX58,PARP12,DLGAP5,SPC25,PARP14,CYP2J2,TAP1,GMPR,KIF23,HERC5,SAMD9,KIF2C,HERC6,TMC1,LGALS3BP,C1orf116,DTX3L,CYP4F11,IFIT1,OAS3,LAMP3,PARP9,HMMR,REC8,MX1,PLSCR1,IFITM3,LAP3,PBK,USP18,FHL2,BLVRA,IFIT3,SNTB1,PI4K2B,TRIM69,AXL,NMI,STAT1,TDRD7,IRF7,CMPK2,IFIH1,IFI6 |
| 3.434e-04 | -7.98 | tube closure | biological process | GO:0060606 | 88 | 26 | 16441 | 2455 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SDC4,RAB23,PRICKLE1,KIF20B,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,BCL10,TSC1,VASP,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,COBL,RARG,DVL2 |
| 3.473e-04 | -7.97 | regulation of MAP kinase activity | biological process | GO:0043405 | 283 | 64 | 16441 | 2455 |
SPRED1,AVPI1,EPHA4,P2RX7,ERBB2,PDGFB,FLT3,ERP29,TP73,PDGFA,RGS3,DUSP10,DAB2IP,RASGRP1,DVL2,SOD1,RIPK2,FZD4,DUSP4,CD40,CDK1,MAP3K6,PTPRJ,STK38,MADD,KIAA1804,NOD2,MAP3K11,RGS14,GAB1,TAB3,TRAF2,PRKAA1,TRIB2,PKN1,GSTP1,DUSP5,BMP2,PDCD10,IRAK1,BMP7,MAP3K9,SORL1,MDFIC,MAPK11,MAP3K7,IQGAP3,SPRY2,SYK,DUSP1,MDFI,MAPKAPK3,PDE5A,ILK,EGFR,MAPKAPK2,INSR,FGF18,ARRB1,EFNA1,FZD5,MAP3K5,CD81,HIPK3 |
| 3.486e-04 | -7.96 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | 835 | 157 | 17758 | 2588 |
IL15RA,PNPLA2,PDGFRL,PLA2G16,ERP29,ELMOD2,LTBP3,GRHL1,ARHGEF37,SIVA1,IL31RA,AOX1,TMEM143,PXMP4,TIPARP,S100A13,TNIP1,BNIP3L,NFE2L1,ARFRP1,ESYT1,PRKRA,CLCN2,IDH1,TYSND1,ARF4,SFXN1,MID1IP1,MPRIP,GPRC5B,AGPAT2,MYLK,EIF4EBP2,NFKBIZ,KLF11,RBM43,CHPT1,STARD13,RMND5A,ALDH6A1,HJURP,SCOC,C6orf106,ASAH1,ADCK5,BMP2K,LMNA,ELF3,PFKL,TBCD,PRKCI,PCYOX1,ADCK2,FNIP1,SELK,STT3B,NTN1,NUP85,PSMA5,FADS2,MRPS33,MMD,PQLC3,ADCK3,MGAT4B,GYLTL1B,FBXO8,KIAA1109,NPHP3,BCL2L13,ZDHHC3,NFIB,CYB5A,PRX,BCAR3,SCARB2,NAAA,FAM64A,CGREF1,AGBL5,SAMD8,ATP1B3,MAL2,TMEM120A,XDH,DYNLRB1,SLC2A4,TUBB4B,CAST,DGKA,FTH1,SNN,NUDT12,AIFM2,KBTBD11,MXD1,EFR3A,N4BP3,BCL6,TAX1BP3,DAB2IP,ECE1,LOXL1,SNX10,GLO1,MYL12A,EBF2,GABARAPL1,PEX5,ABHD12,STAT6,PEX2,SIPA1L1,STAT1,TLE1,XRCC3,EFNA5,MLKL,OTUD5,SORT1,HSP90B1,CENPI,TRAF2,DAP,CDCA3,ZNF219,HDGFRP2,SEPP1,LGALS3BP,TMCC3,PDIA4,IRF2BPL,IL17RB,CAPN2,CST3,SLC35B4,CKS1B,FAM102A,ECI2,FAH,POU6F1,SYPL1,TGIF1,OPLAH,DCAF6,TEF,PIM3,RNPEP,BCAR1,CRTC2,MAMDC4,PLA2G15,FAM3C,ACADM,WDR62,PLOD3,TMEM131 |
| 3.501e-04 | -7.96 | IL-6 Signaling Pathway | WikiPathways | WP364 | 99 | 30 | 4455 | 729 |
CASP3,INPPL1,AKT1,INPP5D,PIK3R1,CASP9,ERBB2,TEC,CD40,FOS,PPP2R3A,CDK5R1,SOCS3,MAPKAPK2,PLCG1,RB1,FYN,RPS6KA2,JAK1,PPP2R5A,IL6ST,PPP2R4,STAT1,SGK1,HDAC1,ERBB3,MAP3K7,HSPB1,PPP2R5D,GAB1 |
| 3.509e-04 | -7.96 | TTGCCAA,MIR-182 | MSigDB lists | TTGCCAA,MIR-182 | 312 | 68 | 17758 | 2588 |
ACVR1,EPAS1,RET,FAM78A,TEX2,EGR3,FAM91A1,MAP1LC3B,KTN1,EPM2A,GRM5,DOK4,ZFP36,MITF,CTTN,BAG4,TRIM8,TMEM68,ARF4,ZMPSTE24,PLCH1,LIMK1,HOXA9,CORO1C,SPRY4,STARD13,FAM134B,ARHGEF3,PPP1R2,NUAK1,ARHGEF7,FLOT1,PDXDC1,PARM1,XPR1,IRF2BPL,UBE2Q2,ADD3,VASP,RIMS3,BHLHE41,OCRL,SLC44A2,CITED2,CNPY3,C9orf72,IGSF3,KDELR1,P2RX4,SYPL1,MMD,TACC1,VAMP3,WHSC1,BCL2L13,TP53INP2,RASA1,TMEM50B,ETS2,SH3BP4,DCUN1D1,PLD1,ATP1B3,L1CAM,TOB1,RARG,DOCK9,KLF7 |
| 3.519e-04 | -7.95 | REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE | MSigDB lists | REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE | 49 | 17 | 17758 | 2588 |
RIPK2,MAPKAPK3,TAB3,RPS6KA1,DUSP4,ELK1,FOS,CDK1,MAPKAPK2,RPS6KA2,IRAK1,NOD2,MAPK11,MAPK7,MAP3K7,PPP2R5D,RPS6KA3 |
| 3.519e-04 | -7.95 | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | MSigDB lists | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | 49 | 17 | 17758 | 2588 |
PSME2,TAP1,PDIA5,PSMD7,PDIA3,PSME1,PSMA4,HLA-A,HLA-B,TAPBP,PSMC2,ERAP1,HLA-C,PDIA6,PSMC1,ERAP2,KDELR1 |
| 3.519e-04 | -7.95 | ZHANG_PROLIFERATING_VS_QUIESCENT | MSigDB lists | ZHANG_PROLIFERATING_VS_QUIESCENT | 49 | 17 | 17758 | 2588 |
CASP3,SOD1,RHOA,PLAUR,ITGA6,CCNB1,GSTP1,CASP4,GNAS,CCND1,CTGF,AXL,BAX,MAP3K11,IGFBP2,ITGAV,HSPB1 |
| 3.534e-04 | -7.95 | gliogenesis | biological process | GO:0042063 | 172 | 43 | 16441 | 2455 |
EMX1,WASF3,NF2,ADGRG1,NDRG1,ARHGEF7,HDAC11,EPHA4,SOX9,HEXB,ERBB2,MPP5,DNER,PICK1,CDKN2C,CTNNB1,PTEN,TFAP2A,SMO,CD9,DUSP10,DAB2IP,ERBB3,ERCC2,HES1,SOD1,RHOA,AKT1,SCRIB,ILK,DAG1,NFIB,CDK5R1,NFIX,PTPRJ,FA2H,AREG,PLPP3,NAB2,MATN2,NRG1,SOX8,DRD1 |
| 3.552e-04 | -7.94 | myxoid-round_cell | COSMIC cancer mutations | myxoid-round_cell | 100 | 28 | 17775 | 2585 |
SPEF2,SMARCA2,ARAP3,HSP90B1,AKT1,GRIK2,GNE,TP53,VARS2,CBL,IDH1,PDXDC1,SPTB,EGFR,PDE11A,CORO1B,GNAS,SS18,RB1,CTNNB1,CDH1,HTT,PTEN,LLGL2,ATP7B,PLK4,PIK3CA,PER3 |
| 3.552e-04 | -7.94 | soft_tissue-fat-liposarcoma-myxoid-round_cell | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-myxoid-round_cell | 100 | 28 | 17775 | 2585 |
SPEF2,SMARCA2,ARAP3,HSP90B1,AKT1,GRIK2,GNE,TP53,VARS2,CBL,IDH1,PDXDC1,SPTB,EGFR,PDE11A,CORO1B,GNAS,SS18,RB1,CTNNB1,CDH1,HTT,PTEN,LLGL2,ATP7B,PLK4,PIK3CA,PER3 |
| 3.552e-04 | -7.94 | ENZYME_BINDING | MSigDB lists | ENZYME_BINDING | 176 | 43 | 17758 | 2588 |
GCLM,EPAS1,RALBP1,SUDS3,TP53,HDAC6,ADAMTSL4,PICK1,TOP2A,CDKN2C,RB1,ANK1,IGF1R,IRAK1,KIF13B,PPME1,RANBP1,DLG1,CDKN2D,CCDC88A,DOCK4,SOD1,PLAUR,PIK3R1,PARP4,AKAP3,NPC2,CD40,BCAR1,RANBP9,RASA1,MAPK8IP1,BCL10,INSR,PRDX3,NFKBIA,PPP2R4,NOD2,FGD6,HDAC1,ABCA1,ZC3HC1,FGD1 |
| 3.556e-04 | -7.94 | cell projection assembly | biological process | GO:0030031 | 267 | 61 | 16441 | 2455 |
TTC8,WASF3,CFAP74,INPPL1,TCTN2,AK7,POC1B,ITGA6,ARHGEF7,RAB23,CCNO,P2RX7,ZMYND10,NCKAP1,EMP2,SSX2IP,PDGFA,RAC2,LRRC6,OCRL,CAPG,FXYD5,CTTN,NTN1,SNX10,RPGR,TTLL1,NUP85,CCDC88A,DNAAF3,DNAI1,SPEF2,BAG4,CELSR2,B9D2,CEP89,CFAP46,FOPNL,RAPGEF2,ANO6,SPATA13,EMP3,EZR,RAB3IP,BBS2,SPAG1,ARHGEF26,CEP162,DZIP1L,ONECUT1,STK26,WDR19,TRAF3IP1,MYLK,RAP2C,FGD6,KLF5,CEP41,ARHGEF4,EHD1,FGD1 |
| 3.560e-04 | -7.94 | actin filament bundle assembly | biological process | GO:0051017 | 48 | 17 | 16441 | 2455 |
SORBS1,RHOA,USH1C,HSP90B1,ADD1,DMTN,EPS8,EZR,LCP1,CORO1B,DPYSL3,ZYX,SWAP70,PDCD10,ARRB1,ESPN,SHROOM2 |
| 3.560e-04 | -7.94 | exocrine system development | biological process | GO:0035272 | 48 | 17 | 16441 | 2455 |
NKX3-1,SOX9,PLXNA1,CLCN2,NFIB,DAG1,EGFR,INSR,IGF1R,FGFR2,TWSG1,BMP7,CST3,PLXND1,SEMA3A,RARG,IGSF3 |
| 3.572e-04 | -7.94 | RYTTCCTG_V$ETS2_B | MSigDB lists | RYTTCCTG_V$ETS2_B | 1031 | 189 | 17758 | 2588 |
SIGIRR,ST13,SSH1,EPHX4,GATA3,DHX8,ITPR2,PDGFB,CMTM6,LTBP3,SH3KBP1,SESN3,SHC3,STIM1,RGS3,OSBPL3,SERINC2,ABCA2,DNM2,POF1B,PIK3CD,MARK1,CITED4,SH3BGRL,CDYL,SLC35C1,KDELR3,ARHGDIB,NKAIN1,LDB2,SLC25A5,ZBTB7B,SPNS3,ARF4,ABR,LCP1,ENPP1,PLCG1,TMEM164,TBC1D17,WDR11,KLF12,MADD,MAP3K11,CAB39,SP6,SERPINI1,ARF6,STARD13,NFKBIE,PPP1R12A,DHPS,RASA2,ETV5,NDUFA4,B4GALNT1,BMP2,CALR,VASP,TIMP1,RINL,ZNRF2,KCNN4,PRICKLE4,ATP5H,FCHO1,FBXL14,FXYD5,PLCB2,MYLIP,RIMS2,CCDC88A,C9orf9,B3GNT7,ELK3,PCDH1,STAT4,HMG20B,CALCRL,DGKH,MAPKAPK2,EPN3,NT5C2,PRKAG2,PLEKHH2,DCK,ITPR1,SH3BP4,AGBL5,ARAP1,APPL2,EGFL7,NR4A2,CTSA,ARPC2,DRP2,JAK3,RPS6KA3,ELK4,TRIP10,PSME2,CAST,DGKA,ETNK1,RASGRP3,FTH1,EGR3,PRKACA,EPS8L2,SS18,ZNF687,SH3BP1,RALB,LMO4,SRR,BCL6,CNNM4,DAB2IP,DIXDC1,PDE4D,SCN2A,SCN3A,FRS3,PPIF,DOCK4,CLCN3,TAF5,KIAA0040,ERBB2IP,DUSP4,ITPR3,CD40,ATP13A2,CCDC149,PTK7,RCAN2,ARHGAP4,RGS14,BIN1,CMAS,FBLIM1,TAB3,CYB561,TRMT2B,ETS1,NFAT5,TEAD3,FZD6,M6PR,WWP2,PDCD10,RNF128,PTEN,LLGL2,ARSG,FAM160A2,MGAT4A,BMP7,CALD1,CKS1B,SGK1,ADAM15,TAGLN2,KLF9,CITED2,GFI1,RBMS2,TGIF1,PGM1,AMFR,PIK3R1,FURIN,RUNX3,LRRC1,CRTC2,PITX2,LDLRAP1,FGFR2,RIN3,RAP2C,NR4A3,OTUB2,HMGA1,FHL1,ZBTB33,DEF6,ARHGEF4,TLL2,PHC1 |
| 3.605e-04 | -7.93 | hemostasis | biological process | GO:0007599 | 530 | 108 | 16441 | 2455 |
PLA2G4A,MYL9,KIF3C,PAPSS2,INPP5D,KLC2,TP53,DGKA,GATA3,F11R,ITPR2,KIF2C,PRKACA,KIF26A,PDGFB,PDGFA,CALM2,WEE1,STIM1,CYP4F11,PLCG2,PIK3CA,IRF2,KIF22,LMAN1,F2R,RASGRP1,TUBA4A,LAMP2,ENPP4,SOD1,AKT1,PRKAR2B,PRKCQ,F12,ATP1B1,CD40,ITPR3,MYL12A,PLCG1,FYN,KCNMB4,ABHD12,AXL,HDAC1,HSPB1,F2RL1,MAFF,PRKAR1A,SERPINE2,CD63,ITGA6,DGKQ,HABP4,SELL,KIF23,CALM3,RACGAP1,DOCK11,FBLN1,MERTK,ITGA2B,FZD6,SIRPA,RAC2,ITGA3,TIMP1,GATA2,CD9,PRKG1,AK3,WNT3A,DGKG,SYK,ATP2B1,RHOA,PLSCR1,PLAUR,CALM1,ANO6,PIK3R1,HMG20B,C1GALT1C1,PDE5A,YES1,ILK,BCAR1,KIF11,GNA11,RHOB,DGKE,PDE11A,RASGRP2,DGKH,GNAS,SERPINA1,PRCP,ITPR1,ARRB1,CENPE,ITGAV,ATP1B3,CBX5,TRPC3,L1CAM,DOCK9,IRF1,EHD1 |
| 3.607e-04 | -7.93 | CELLULAR_PROTEIN_METABOLIC_PROCESS | MSigDB lists | CELLULAR_PROTEIN_METABOLIC_PROCESS | 1099 | 200 | 17758 | 2588 |
CASP3,SIGIRR,TNK1,ACVR1,ST13,AGRN,SSH1,RET,FBXO2,IL18,ISOC2,HDAC6,ERP29,PICK1,DAPK2,CDKL5,P4HB,IL31RA,CAPG,FUT1,DUSP10,RP2,PPP1CA,PTPRE,METAP2,NEK4,PTPN18,MARK1,TNIP1,RNF11,ERP44,GALNT7,LOXL2,ANLN,ICMT,STK17B,VCP,HS6ST1,MID1IP1,HPSE,DOLPP1,LIMK1,MYLK,PPP2R4,MAP3K11,BMP1,POMT1,ARF6,HSPB1,PCSK5,PRKAA2,CDK17,PEX6,DHPS,DNAJB2,PRKAA1,MERTK,DUSP5,TSPAN7,RABGGTA,ATG4A,B3GALNT1,IGF1R,TIMP1,PAIP2B,NECAB3,RPL39,PAK2,FBXO7,TBCD,PRKCI,PRKG1,MAP3K9,DAPK1,TPST1,STT3B,PIM1,GAD1,MYLIP,CCDC88A,NAGPA,PIGC,DDB2,QSOX1,UFD1L,PTPRH,MGAT4B,STRADB,EIF2AK1,ILK,NUBP1,EGFR,RASA1,NMT2,GLCE,STK17A,MAPKAPK2,MMP15,TSC1,INSR,FNTA,AURKA,ALG2,JAK3,CTBP1,DMPK,NF2,ST14,HDAC11,PDIA5,ERBB2,TESK2,MAPK4,ZFYVE9,EPM2A,CCND1,PPME1,PLK4,RPN2,PHKA2,LMAN1,PDIA6,LOXL1,F2R,ATG4D,SEPHS1,MAP3K3,SIRT1,CDKN2AIP,BAG4,AKT1,COG2,PTPRU,PTPN9,CDC20,COX11,DUSP4,CBL,MAP3K6,CASP4,ZMPSTE24,PTPRJ,IDE,STK38,KIAA1804,STAT1,NRG1,HS3ST3B1,RPL22,MAPK12,WASF3,PINK1,DYRK3,MAN1A2,CTSB,BACE1,CTSZ,TGFBR1,FBXO6,POMGNT1,PKN1,SBF1,TRIB2,AIP,PPP2R3A,WWP2,FUT2,PTEN,CDK16,CENPJ,MGAT4A,FUT8,RRBP1,SGK3,SGK1,WWP1,ERBB3,SLC35A1,GCNT1,AMFR,PARP4,FURIN,UBE2A,YES1,PRDX4,TXK,BCL10,CASP7,ACVRL1,PLOD2,UBE2D2,NR4A3,CSGALNACT1,ERAP1,HMGA1,PLOD3,UBE2C,CD81,HIPK3,ABCG1 |
| 3.618e-04 | -7.92 | FERM/acyl-CoA-bd_prot_3-hlx | interpro domains | IPR014352 | 49 | 17 | 18293 | 2672 |
EPB41L5,ACBD5,FARP1,FRMD4A,NF2,FRMD6,ACBD3,EZR,FRMD4B,PLEKHH2,DBI,ECI2,EPB41L4B,EPB41L4A,TLN2,MYLIP,FARP2 |
| 3.619e-04 | -7.92 | GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_DN | 192 | 46 | 17758 | 2588 |
DOC2A,DHPS,GCAT,TMEM41B,NDRG1,KIF2C,GPSM2,VASH1,PIGL,TNFSF9,SH3KBP1,BMP2K,ZDHHC21,WEE1,CTSC,TACC2,PLK4,KIF22,MAP3K7,TIAM1,TRAK2,CENPA,PLSCR1,KIF20A,ASXL1,VAMP3,ACO1,PTGER4,FBXO8,FBXO9,TRIM35,CDCA2,AURKB,CCNF,ANLN,CDC25C,CDK1,MSL1,CSTF2,CHMP4B,ARF6,C17orf75,RTN3,ESPL1,PDPR,NR2C2 |
| 3.619e-04 | -7.92 | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN | 192 | 46 | 17758 | 2588 |
DDX58,CCDC109B,PARP12,IL15RA,IL15,PSME2,HLA-E,HLA-F,TAP1,HERC6,PRRG4,ICAM1,CDS1,RCN1,TYMP,RALB,FUT1,SRP54,RAB20,PIM1,ETV7,APOBEC3G,MX1,ARAP2,PLSCR1,KIAA0040,LAP3,LITAF,UBE2A,RNF19B,CASP4,PSMA4,BCAR3,CASP7,CTNS,STAT6,NMI,SECTM1,STAT1,NOD2,TDRD7,IRF7,IFIH1,APOL2,ISOC1,IRF1 |
| 3.619e-04 | -7.92 | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | 192 | 46 | 17758 | 2588 |
KLF2,DHPS,UBE2Z,SELL,AES,NENF,TP53I11,PHF1,H1FX,CDK14,CAPN2,DOPEY2,RNF220,CES2,PAIP2B,DDHD2,KLF3,ZNF692,GLB1L2,TAGLN2,PHKA2,CNPY3,XKR8,FARP2,CERS2,NAGPA,PODXL2,KIAA0040,PTPRU,FOXJ2,DCHS1,ATP10D,RHOB,CD83,MAN2A2,HLA-B,NUCB1,NAAA,MSL1,DGCR2,SPAG7,PRKCDBP,HSPB1,CTBP1,JARID2,CTDSP1 |
| 3.619e-04 | -7.92 | GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP | MSigDB lists | GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP | 192 | 46 | 17758 | 2588 |
SCN5A,LASP1,PARP12,DGKQ,ERI2,PBX3,UBE2Q1,MAP1LC3B,EXT2,ICAM1,C16orf74,KIF5B,SESN3,GRHL1,PPP1R10,MGAT1,SLC44A1,ANKRD12,TMBIM6,CD70,MAP3K7,MYLIP,ITM2C,ASXL1,BTNL9,KIAA0040,COQ10B,LPGAT1,ERBB2IP,DUSP4,BCL2L13,SESN1,CDK5R1,FRMD4B,CD83,PDE11A,NFIX,TRAM2,PTPRJ,RBL1,DGAT2,GLCCI1,TOB1,RARG,HIPK3,CTDSP1 |
| 3.629e-04 | -7.92 | execution phase of apoptosis | biological process | GO:0097194 | 79 | 24 | 16441 | 2455 |
CASP3,ADD1,AKT1,ACVR1C,SHARPIN,BLCAP,PRKCQ,BCAP31,CASP4,LMNA,TOP2A,FNTA,CASP7,CDH1,CTNNB1,H1F0,DNM1L,STK26,MADD,PAK2,GPER1,AIFM3,OCLN,XKR8 |
| 3.636e-04 | -7.92 | positive regulation of immune response | biological process | GO:0050778 | 582 | 117 | 16441 | 2455 |
LAMP1,UNC93B1,TRIM5,IL15,INPP5D,RPS6KA1,PSME2,CUL1,P2RX7,GATA3,IL27RA,PSME1,ITPR2,PRKACA,CACNB4,CALM2,CD46,PSMD1,RPS6KA2,ELMO2,IL6ST,PSMC2,PLCG2,PIK3CA,PDE4D,PIK3CD,NFKB2,SCARA3,LGMN,SMAGP,RASGRP1,SIRT1,CD55,RIPK2,TNIP1,ITCH,CR2,PRKCQ,CD40,DUSP4,ITPR3,PLCG1,PTPRJ,FYN,GPRC5B,PSMD3,LIMK1,STAT6,NOD2,IRF7,F2RL1,PSMC1,PPP2R5D,DDX58,HSP90B1,TAB3,THEMIS2,TRAF2,CTSB,HLA-E,PSMD7,CALM3,BTN3A1,PSMD10,PLD2,NCKAP1,TEC,HLA-A,VASP,IRAK1,PTEN,PIK3AP1,PAK2,BAX,MAPK11,MAPK7,MAP3K7,CNPY3,SYK,MSH6,PSMA5,SOCS5,KLK5,PLSCR1,PSMB4,MAPKAPK3,MICB,CALM1,PIK3R1,RGCC,WHSC1,YES1,CYFIP2,ELK1,FOS,BCAR1,PSMA4,BCL10,TXK,GPLD1,MAPKAPK2,CTSL,HLA-B,PVRL2,PELI2,ITPR1,NFKBIA,NLRC5,NR4A3,UBE2D2,KLK7,ARPC2,FZD5,JAK3,IFIH1,RPS6KA3,TMEM173 |
| 3.637e-04 | -7.92 | HTLV-I infection | KEGG pathways | hsa05166 | 258 | 61 | 6908 | 1076 |
ELK4,IL15RA,IL15,HLA-E,HLA-F,PTTG1,XIAP,TP53,TGFBR1,MRAS,BCL2L1,PDGFB,ETS1,PRKACA,APC2,ICAM1,HLA-A,FZD6,CCND1,CALR,CDKN2C,PDGFA,RB1,PCNA,CTNNB1,ZFP36,RANBP1,DLG1,PIK3CA,BAX,PIK3CD,HLA-C,TLN2,NFKB2,WNT3A,MYBL1,DVL2,MAP3K3,AKT1,WNT10B,FZD4,CDC20,PIK3R1,MYBL2,ELK1,CD40,POLD3,SLC25A5,FOS,FZD7,IL1R1,CRTC2,HLA-B,JAK1,SLC25A4,ETS2,NFKBIA,E2F1,FZD5,CCNB2,JAK3 |
| 3.637e-04 | -7.92 | HTLV-I infection | KEGG pathways | ko05166 | 258 | 61 | 6908 | 1076 |
ELK4,IL15RA,IL15,HLA-E,HLA-F,PTTG1,XIAP,TP53,TGFBR1,MRAS,BCL2L1,PDGFB,ETS1,PRKACA,APC2,ICAM1,HLA-A,FZD6,CCND1,CALR,CDKN2C,PDGFA,RB1,PCNA,CTNNB1,ZFP36,RANBP1,DLG1,PIK3CA,BAX,PIK3CD,HLA-C,TLN2,NFKB2,WNT3A,MYBL1,DVL2,MAP3K3,AKT1,WNT10B,FZD4,CDC20,PIK3R1,MYBL2,ELK1,CD40,POLD3,SLC25A5,FOS,FZD7,IL1R1,CRTC2,HLA-B,JAK1,SLC25A4,ETS2,NFKBIA,E2F1,FZD5,CCNB2,JAK3 |
| 3.655e-04 | -7.91 | parietal_lobe | COSMIC cancer mutations | parietal_lobe | 58 | 19 | 17775 | 2585 |
NF2,AKT1,RET,TP53,IDH1,GNA11,EGFR,GNAS,TP73,CDKN2C,RBM23,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,MSH2,RTKN2,MSH6 |
| 3.656e-04 | -7.91 | SH3_1 | pfam domains | PF00018 | 97 | 28 | 16629 | 2504 |
SORBS1,PACSIN2,TRIP10,SH3D19,EPS8,SPATA13,SORBS3,TEC,YES1,DOCK5,BCAR1,SNX9,EPS8L2,RASA1,SH3RF2,TXK,PLCG1,FYN,NOXA1,ARHGEF37,PLCG2,DLG1,OSTF1,ARHGAP4,DLG3,ARHGEF9,NGEF,ARHGEF4 |
| 3.667e-04 | -7.91 | TMFOUR | prints domains | PR00259 | 30 | 12 | 4759 | 661 |
TSPAN15,CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN13,TSPAN1,CD81,TSPAN17,TSPAN7,TSPAN33 |
| 3.673e-04 | -7.91 | vesicle membrane | cellular component | GO:0012506 | 452 | 93 | 17570 | 2579 |
SUN1,LAMP1,SLC2A4,IL15RA,SLC2A8,ATP8A1,SYTL4,SAYSD1,SNX9,PHLDA1,APPBP2,SH3KBP1,PICK1,CD46,ATP6V0B,AP1M2,N4BP3,SMO,DNM2,RAB20,PACSIN1,LMAN1,RAB27B,FLOT2,CPE,MYRIP,SMAGP,LAMP3,MYO5B,LAMP2,SEC23A,CLCN3,FZD4,SNTB2,RAB38,MCFD2,ULK2,GABARAPL1,ATP13A2,GPRC5B,AREG,RAB11FIP1,NRGN,COPG1,ARFGEF3,ANXA3,TAOK2,PACSIN2,CD63,HLA-E,BACE1,HLA-F,TRAF2,RAB23,ITGA2B,HLA-A,FZD6,MARCH8,RAC2,ZNRF2,SNX18,OCRL,ZDHHC13,CD9,CADPS2,HLA-C,WNT3A,GAD1,GPR161,CAMK2G,TMED2,KDELR1,SNX7,SYPL1,RAB3B,VAMP3,ATP8B3,FNDC3A,C3orf58,EGFR,HLA-B,LDLRAP1,HTT,RAB11FIP2,TMEM30A,ITPR1,RAB31,DYSF,ARRB1,GPER1,FZD5,TBC1D4,TMEM173 |
| 3.679e-04 | -7.91 | BENPORATH_ES_CORE_NINE_CORRELATED | MSigDB lists | BENPORATH_ES_CORE_NINE_CORRELATED | 100 | 28 | 17758 | 2588 |
NFE2L3,PAX6,NFKBIE,FOXM1,SOX9,MYBL2,WHSC1,TFAP2C,HTATIP2,RUNX3,NFIB,CALR,RBL1,LMO4,NMI,ELF5,WWTR1,STAT1,E2F1,TLE1,KLF5,KLF11,HMGA1,MYBL1,ETV7,E2F8,IRF1,MDFI |
| 3.679e-04 | -7.91 | HUMMERICH_SKIN_CANCER_PROGRESSION_DN | MSigDB lists | HUMMERICH_SKIN_CANCER_PROGRESSION_DN | 100 | 28 | 17758 | 2588 |
MYL9,GAA,BCAM,COL6A2,RPS6KA1,UBE2A,AES,EPHA1,ILK,PRKACA,ECI1,EFNB1,LTBP3,NRP2,WWP2,FECH,PTPRF,ATP6V0B,ZYX,PDLIM3,ACADSB,BMP1,PRKCI,PPP1CB,FHL1,ACSL4,MAPK7,COL16A1 |
| 3.692e-04 | -7.90 | regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001236 | 157 | 40 | 16441 | 2455 |
GCLM,ACVR1,LGALS3,ITGA6,TRAF2,RET,PDIA3,TGFBR1,BCL2L1,GSTP1,ICAM1,LMNA,SP100,SRPX,PAK2,DAPK1,BAX,TNFRSF12A,PPP1CA,CTTN,FAIM,MAPK7,ITM2C,TMBIM1,AKT1,GCLC,STRADB,PELI3,FAS,BCL10,FYN,HTT,SCG2,MADD,NRG1,ITGAV,GPER1,UNC5B,IFI6,ZC3HC1 |
| 3.699e-04 | -7.90 | ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | MSigDB lists | ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 140 | 36 | 17758 | 2588 |
ACVR1,SORBS1,AGRN,REPS2,CDKN1C,MPZL1,EPS8,ERBB2,TGFBR1,GDF15,FLT3,ZFYVE9,PICK1,TGFBR3,IGF1R,SHC3,ERBB3,MAP3K7,CITED2,FRS3,AKT1,RGMB,PTPRU,PIK3R1,ERBB2IP,ROR1,CBL,BCAR1,EGFR,PTPRF,PTPRJ,FNTA,INSR,ACVRL1,LTBP2,GAB1 |
| 3.704e-04 | -7.90 | soft_tissue-fibrous_tissue_and_uncertain_origin-alveolar_soft_part_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-alveolar_soft_part_sarcoma | 45 | 16 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,JAK3 |
| 3.704e-04 | -7.90 | alveolar_soft_part_sarcoma | COSMIC cancer mutations | alveolar_soft_part_sarcoma | 45 | 16 | 17775 | 2585 |
AKT1,RET,TP53,ERBB2,IDH1,FLT3,EGFR,GNAS,RB1,CTNNB1,CDH1,PTEN,FGFR2,SMO,PIK3CA,JAK3 |
| 3.713e-04 | -7.90 | ATGTACA,MIR-493 | MSigDB lists | ATGTACA,MIR-493 | 307 | 67 | 17758 | 2588 |
CTDSPL,ARFGEF1,UBE2Q1,FAM91A1,SNX9,ZNF385B,GRM5,SS18,APLP2,SIPA1L2,ACAP2,SRPX,CASC4,KLF3,REEP1,IRF2,DAB2IP,PDE4D,ANO4,TMTC1,MARK1,FZD4,SAT1,ZFAND5,SP4,IRX3,TRAM2,SH2D3C,LRIG1,MADD,OVOL1,CTNND1,IRF7,HS3ST3B1,PPP2R5D,GAB1,TAB3,PBX3,GABRG2,INTS8,ZFX,UBE2Q2,PPP1R10,RIMS3,BHLHE41,BRD7,FNIP1,CITED2,PIKFYVE,GAD1,CHSY3,PDGFC,PHF20L1,LCA5,PIK3R1,ANTXR1,MAP1B,USP6,BTG1,SERTAD2,KBTBD2,ZMYND19,DCUN1D1,PCDH19,ZMIZ1,TBC1D4,DOCK9 |
| 3.715e-04 | -7.90 | macromolecule glycosylation | biological process | GO:0043413 | 344 | 75 | 16441 | 2455 |
GALNT12,NANS,MGAT5B,ART5,EXT2,MUC16,MUC4,FUT1,RPN2,LMAN1,TFG,TIPARP,MGAT5,SIRT1,SEC23A,GALNT7,SLC17A5,B3GALNT2,MCFD2,ARF4,VCP,MAN2A2,DDOST,AREG,DOLPP1,GNPTAB,B4GALT3,POMT1,ST3GAL1,POMGNT2,CMAS,TRAPPC10,MAN1A2,GNE,PDIA3,CTSZ,B4GALT4,POMGNT1,ADAMTSL4,B4GALNT1,CALR,B3GALNT1,FUT2,CTSC,MGAT1,A4GALT,MGAT4A,ALG13,FUT8,UBE2J1,STT3B,SLC35A1,PPP6R1,TMED2,TRAK2,GCNT1,GFPT1,B3GALT6,NAGPA,B3GNT7,MLEC,B3GNT2,MGAT4B,GYLTL1B,PARP4,C1GALT1C1,COL7A1,FUCA1,GALNT3,SERPINA1,UAP1,GLB1,CTSA,B4GAT1,ALG2 |
| 3.715e-04 | -7.90 | protein glycosylation | biological process | GO:0006486 | 344 | 75 | 16441 | 2455 |
GALNT12,NANS,MGAT5B,EXT2,ART5,MUC16,MUC4,FUT1,RPN2,LMAN1,TFG,TIPARP,MGAT5,SIRT1,SEC23A,SLC17A5,GALNT7,B3GALNT2,MCFD2,ARF4,VCP,MAN2A2,DDOST,AREG,GNPTAB,DOLPP1,POMT1,B4GALT3,ST3GAL1,POMGNT2,CMAS,TRAPPC10,MAN1A2,GNE,PDIA3,CTSZ,POMGNT1,B4GALT4,ADAMTSL4,B4GALNT1,CALR,B3GALNT1,FUT2,CTSC,MGAT1,A4GALT,MGAT4A,ALG13,FUT8,UBE2J1,STT3B,SLC35A1,PPP6R1,TMED2,TRAK2,GCNT1,NAGPA,B3GALT6,GFPT1,B3GNT7,B3GNT2,MLEC,MGAT4B,PARP4,GYLTL1B,C1GALT1C1,COL7A1,FUCA1,GALNT3,SERPINA1,UAP1,CTSA,GLB1,ALG2,B4GAT1 |
| 3.720e-04 | -7.90 | dysplasia-carcinoma_in_situ | COSMIC cancer mutations | dysplasia-carcinoma_in_situ | 25 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,GNA11,EGFR |
| 3.721e-04 | -7.90 | Golgi stack | cellular component | GO:0005795 | 124 | 33 | 17570 | 2579 |
SORT1,GOLIM4,B4GALT4,BCAP31,NCS1,HLA-A,CHPF,INPP5E,FUT2,OCRL,NECAB3,FUT8,FUT1,SORL1,RAB27B,TMED2,GCNT1,SULF2,B3GALT6,NAGPA,MOB4,CHSY3,ATL1,COG2,FURIN,GALNT3,NUCB1,ARAP1,CSGALNACT1,CANT1,B4GALT3,ST3GAL1,GOLGB1 |
| 3.744e-04 | -7.89 | SMALL_GTPASE_REGULATOR_ACTIVITY | MSigDB lists | SMALL_GTPASE_REGULATOR_ACTIVITY | 67 | 21 | 17758 | 2588 |
DOCK4,ARHGEF3,FARP1,ARAP3,ARHGEF11,RAPGEF2,RALBP1,RASA2,ARFGEF1,RASGRP3,ARHGDIB,RASA1,ARHGEF10L,RCBTB2,RANBP1,MADD,ARAP1,ARFGAP3,ARHGAP4,TIAM1,FARP2 |
| 3.753e-04 | -7.89 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK | 135 | 35 | 17758 | 2588 |
SORT1,ALDH6A1,PNPLA2,PLA2G16,ZNF219,SEPP1,ERP29,LTBP3,TMCC3,EFR3A,PFKL,AOX1,PCYOX1,FAM102A,DAB2IP,PXMP4,FADS2,PQLC3,ADCK3,NFE2L1,FBXO8,PIM3,BCL2L13,IDH1,BCAR3,SFXN1,SCARB2,PEX5,GPRC5B,AGPAT2,PLA2G15,XRCC3,ATP1B3,ACADM,CHPT1 |
| 3.760e-04 | -7.89 | GSE13306_TREG_RA_VS_TCONV_RA_UP | MSigDB lists | GSE13306_TREG_RA_VS_TCONV_RA_UP | 187 | 45 | 17758 | 2588 |
KLF2,REPS2,UBE2Z,GABRG2,CNTNAP2,ZNRF3,CDIPT,OAT,CPNE2,SLC44A2,ADAM15,RAB20,MDFIC,RTKN2,F2R,SLC12A2,ERMP1,CELSR2,HN1L,S100A4,MGAT4B,PLEKHO1,KCTD20,DIAPH2,ERP44,CBL,GLT8D2,C4orf27,MAP1B,PRIM1,TXK,CXXC4,IDE,DDOST,ANKRD6,FGF18,DBI,SECTM1,UBE2D2,MDH1,ATP6V1C1,ARPC2,SHOX2,MAMDC2,USP43 |
| 3.760e-04 | -7.89 | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN | 187 | 45 | 17758 | 2588 |
DDX58,PARP12,CDKN1C,IL15,PARP14,TRIM5,PSME2,TAP1,SMARCAL1,HERC5,IL27RA,FBXO6,HERC6,SLC25A43,SAC3D1,GNS,DTX3L,TNS3,PIK3AP1,METTL7A,IFIT1,OAS3,LAMP3,PARP9,MX1,B3GALT6,KIAA1841,PLSCR1,IFITM3,LAP3,USP18,BLVRA,EAF2,IFIT3,ATP10D,SCARB2,C19orf66,TRIM69,SECTM1,STAT1,IRF7,CMPK2,SLC31A2,IFIH1,IFI6 |
| 3.760e-04 | -7.89 | MCBRYAN_PUBERTAL_BREAST_6_7WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_6_7WK_UP | 187 | 45 | 17758 | 2588 |
CD99,LASP1,SLC2A4,SORBS1,EPAS1,ATP8A1,SOX9,SOD2,TGFBR1,ETS1,CA8,SIRPA,RAD23A,APLP2,PTEN,IL6ST,DNM2,TMEM143,DAPK1,GYS1,STEAP3,GM2A,CPD,FADS2,TIMP2,AKT1,GUSB,FZD4,SNTB2,LPGAT1,PIK3R1,KIF1C,TNS1,TCF7,ZBTB7B,NFIB,MAPK8IP1,NFIX,DPYSL3,GNAS,CANT1,EIF4EBP2,NR2C2,EHD1,EGLN1 |
| 3.760e-04 | -7.89 | GSE1460_DP_VS_CD4_THYMOCYTE_UP | MSigDB lists | GSE1460_DP_VS_CD4_THYMOCYTE_UP | 187 | 45 | 17758 | 2588 |
CD99,TXN,CHCHD7,TBC1D1,ARHGEF7,MTL5,ASL,DHX8,PHLPP1,MNS1,ECI1,SAP130,CDKN2C,NAPG,METTL7A,FBXO7,MITF,TBCD,PLK4,DAPK1,FAIM,RAG1,GFI1,PSMA5,LOC81691,ORAI2,CASK,ALDH2,TIMP2,MPP1,CORO2A,LRRC1,EAF2,DGKE,FECH,NEIL1,PEX5,FA2H,ACYP1,NEIL3,WDR19,DHTKD1,SERPINI1,PLXND1,PPP2R2D |
| 3.760e-04 | -7.89 | REACTOME_DNA_REPLICATION | MSigDB lists | REACTOME_DNA_REPLICATION | 187 | 45 | 17758 | 2588 |
SPC25,PSME2,CENPI,NDC80,ERCC6L,CDCA8,PSMD7,KIF23,PSMD10,NUF2,PSME1,KIF2C,CENPN,CKAP5,RB1,PCNA,PSMD1,CCNA2,PSMC2,CDKN1B,BUB1,KNTC1,NUP85,PSMA5,PLK1,ZWINT,CENPA,KIF20A,PSMB4,B9D2,CDC20,AURKB,POLD3,SKA1,PSMA4,GINS4,PRIM1,PPP2R5A,PSMD3,E2F1,NUP37,SGOL1,PPP2R5D,PSMC1,RAD21 |
| 3.770e-04 | -7.88 | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | 203 | 48 | 17758 | 2588 |
PARP12,GRHL2,HOXB7,PARP14,TUBB4B,HLA-E,CDCA3,SOD2,OSGIN2,KCTD12,TRIB2,SEPP1,MOCS1,LGALS3BP,DAPK2,SP100,PPP1R10,METTL7A,FJX1,TRIM21,IRF2,IFIT1,CASD1,TSPAN33,PARP9,MX1,TRIM8,MMD,PRSS23,CAPN6,SEPT6,USP18,FAM73B,ELK1,MEST,IFIT3,CDK5R1,FAS,CASP7,CSF1,STAT1,IRF7,CMPK2,OSR1,RBM43,IFIH1,LIFR,IRF1 |
| 3.775e-04 | -7.88 | antigen processing and presentation of peptide antigen | biological process | GO:0048002 | 188 | 46 | 16441 | 2455 |
UNC93B1,KIF3C,SEC61G,HLA-E,PSME2,HLA-F,KLC2,PSMD7,TAP1,PDIA3,KIF23,PSMD10,RACGAP1,PSME1,KIF2C,KIF26A,BCAP31,HLA-A,MARCH8,CALR,PSMD1,AP1M2,PSMC2,DNM2,KIF22,HLA-C,CTSD,LGMN,PSMA5,ERAP2,SEC23A,SEC61B,PSMB4,UBE2A,KIF11,PSMA4,DCTN6,CTSL,HLA-B,TAPBP,PSMD3,CTSV,ERAP1,ITGAV,CENPE,PSMC1 |
| 3.777e-04 | -7.88 | nitric oxide metabolic process | biological process | GO:0046209 | 32 | 13 | 16441 | 2455 |
CALM2,P2RX4,DDAH1,NQO1,AKT1,CALM1,DNM2,CALM3,SLC7A2,SPR,POR,ZDHHC21,CYP1B1 |
| 3.791e-04 | -7.88 | MACROMOLECULE_LOCALIZATION | MSigDB lists | MACROMOLECULE_LOCALIZATION | 230 | 53 | 17758 | 2588 |
NFKBIE,PEX6,GGA1,TP53,PDIA3,APBA1,ERP29,SNX9,BARD1,AIP,ZFYVE9,APPBP2,PDIA4,CKAP5,ATG4A,CALR,ZFYVE16,CARD8,AP1M2,CDH1,PPP1R10,LMAN2L,KIF13B,REEP1,BCL6,ARL4D,F2R,TRAM1,RPGR,KDELR1,ATG4D,MDFI,NAGPA,AKT1,COG2,STRADB,ICMT,VCP,EGFR,OPTN,KLHL2,TSC1,SCG2,SHROOM3,NOD2,ARFGAP3,CTSA,KPNA2,LTBP2,SHROOM2,CD81,ABCA1,ABCG1 |
| 3.805e-04 | -7.87 | GCM_MAPK10 | MSigDB lists | GCM_MAPK10 | 81 | 24 | 17758 | 2588 |
FAM171B,MBP,TACC1,TEF,SCD5,LRP4,NDRG2,SLC1A3,BBS2,NCS1,PLEKHB1,GPRC5B,ANKS1B,PHLPP2,DDHD2,DLG1,SERPINI1,TMOD2,ARNT2,PDXK,BTBD3,CBX7,CAMK2G,NIPA1 |
| 3.808e-04 | -7.87 | TPR | prosite domains | PS50005 | 106 | 30 | 11866 | 1802 |
TTC8,TMTC1,ST13,LONRF3,CEP70,TMTC3,DNAJC3,KLC2,TTC7A,EMC2,GPSM2,TMTC2,IFIT3,NPHP3,TANC1,UNC45B,AIP,SPAG1,APPBP2,TTC21B,RGPD5,PEX5,TTC12,FICD,P4HA2,KLC3,CABIN1,IFIT1,TTC9,TANC2 |
| 3.823e-04 | -7.87 | - | gene3d domains | 1.10.238.10 | 260 | 62 | 9988 | 1574 |
MYL9,SLC25A24,REPS2,CAPN12,S100A11,SLC25A13,CALB2,RHBDL3,DGKA,CALM3,EFHD2,RASGRP3,NUCB2,S100A2,REPS1,HPCAL4,NCS1,PPP2R3A,SDF4,PLS3,CALM2,RCN1,CAPN2,NECAB3,CABP1,PLCB2,DGKG,S100A13,RASGRP1,S100A6,CHP1,GCA,KCNIP3,TBC1D8B,STAT4,S100A4,CALM1,UTRN,PLS1,CAPNS1,AIF1L,CBL,MCFD2,MYL12A,LCP1,NIN,RASGRP2,NUCB1,PLCG1,PLCH1,DUOX1,STAT6,CGREF1,NKD1,STAT1,S100A5,EFCAB14,PKD2,PPP2R3C,DRP2,CAPN1,EHD1 |
| 3.841e-04 | -7.86 | PDZ | prosite domains | PS50106 | 145 | 38 | 11866 | 1802 |
LMO7,FRMPD3,USH1C,ARHGEF11,MPP5,APBA1,SLC9A3R2,PICK1,SNTA1,SIPA1L2,RGS12,RGS3,DLG1,TAX1BP3,DLG3,MAST4,TIAM1,RIMS2,DVL2,CASK,PARD3B,RAPGEF2,SNTB2,MPP1,SCRIB,ERBB2IP,SNTB1,RHPN1,PRX,PDLIM3,GRID2IP,TJP3,SHROOM3,LIMK1,SIPA1L1,MPP2,SHROOM2,APBA2 |
| 3.866e-04 | -7.86 | MARSON_BOUND_BY_E2F4_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_E2F4_UNSTIMULATED | 692 | 133 | 17758 | 2588 |
CASP3,TAP1,NDC80,DNAJB11,KIF2C,BARD1,CENPN,FANCI,MAGOHB,SIVA1,PASK,TMEM143,KIF22,STK35,PLK1,TDP1,LOC81691,CENPA,PBK,CKAP2L,TNFAIP8L1,AURKB,PIF1,CCNF,ANLN,CDK1,PRIM1,GDE1,ZNF367,AGFG2,KPNA2,RECQL,HJURP,ALDH6A1,KIF23,RACGAP1,TFAP4,ATP5H,RANBP1,MSH2,NEK2,OPN3,USP1,ZMYM1,NUP85,UFD1L,KIF20A,CEP89,MYBL2,NUBP1,FAM64A,TIMM8A,DCK,CDCA5,AURKA,OSCP1,CCNB2,ARHGAP11A,SPC25,DLGAP5,IQGAP1,APOO,TP53,TESK2,NUF2,STIL,MNS1,KCTD9,CCNA2,PLK4,VAT1,RPN2,FIGNL1,CDC20,CDCA2,NUSAP1,SLC11A2,DNAJB14,CDC25C,KCTD2,TAPBP,DDOST,CDK19,RBL1,STAT1,SGOL1,GEN1,HSP90B1,MZT1,DEPDC1,DCAF7,CENPI,CIT,CCM2,CDCA3,CDCA8,ERI2,ERCC6L,NTAN1,HDGFRP2,IFT27,TOP2A,C16orf59,FAM111A,MDM1,PRC1,CKS1B,BUB1,HSPA13,MXD3,MAP3K7,TMX1,MSH6,SMC4,HMMR,SHMT1,ASPM,DBR1,STMN3,CCDC34,POLD3,SKA1,KIF11,BORA,NEIL3,ZMYND19,E2F1,ETAA1,CENPE,NUP37,UBE2C,ESPL1,MELK |
| 3.882e-04 | -7.85 | reactive nitrogen species metabolic process | biological process | GO:2001057 | 36 | 14 | 16441 | 2455 |
CALM2,P2RX4,DDAH1,MARC1,NQO1,AKT1,CALM1,DNM2,CALM3,SLC7A2,SPR,POR,ZDHHC21,CYP1B1 |
| 3.884e-04 | -7.85 | angiogenesis | biological process | GO:0001525 | 295 | 66 | 16441 | 2455 |
ACVR1,HSPG2,EPAS1,COL18A1,IL18,EGR3,VASH1,PDGFA,NOV,TYMP,CTGF,CTNNB1,PIK3CA,DAB2IP,EPHB4,NOTCH3,CYP1B1,SIRT1,SAT1,HTATIP2,LOXL2,EDNRA,PGF,PTGS2,HS6ST1,HPSE,TBX1,PNPLA6,KLF5,PLXND1,UNC5B,E2F8,ADGRG1,TGFBR1,ETS1,SRPX2,NRP2,GBX2,E2F7,PDCD10,CYR61,PTEN,BAX,ADAM15,TNFRSF12A,MYDGF,MAP3K7,SYK,ELK3,NR4A1,CALCRL,EPHA1,RHOB,GPLD1,ARHGAP24,FGFR2,SCG2,ACVRL1,PRCP,FGF18,ERAP1,EGFL7,HOXB13,ITGAV,EFNA1,FZD5 |
| 3.887e-04 | -7.85 | protection from natural killer cell mediated cytotoxicity | biological process | GO:0042270 | 6 | 5 | 16441 | 2455 |
HLA-B,HLA-E,SERPINB9,HLA-A,TAP1 |
| 3.888e-04 | -7.85 | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN | MSigDB lists | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN | 214 | 50 | 17758 | 2588 |
LTBP1,INPPL1,ALDH6A1,IGFBP6,FOXM1,ST14,CTDSPL,SDC4,DGKA,AKAP17A,IL13RA1,PDXDC1,BEX2,AIP,CKAP5,KIF5B,ALG13,SGK1,ECE1,CACNA1D,LGMN,SLC35A1,GM2A,PSMA5,MED22,TUBA4A,UFD1L,COG2,AMFR,DRAP1,CDC20,EIF2AK1,ARHGDIB,SAV1,MCFD2,ABR,NUCB1,DDAH1,HS6ST1,CD8A,INSR,FGFR2,RND3,STK38,AMMECR1,WWTR1,MADD,SPINT2,ATP1B3,ARPC2 |
| 3.901e-04 | -7.85 | GSE2706_UNSTIM_VS_8H_LPS_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_DC_DN | 182 | 44 | 17758 | 2588 |
TXN,SPC25,IL15,PARP14,PSME2,UBE2Z,PGAP1,DUSP5,MXD1,ICAM1,RCN1,DTX3L,ITGB8,DRAM1,F2R,DUSP1,PCGF5,ARAP2,RIPK2,TNIP1,KIAA0040,STAT4,LYRM1,C3orf52,NUB1,PIM3,CRISPLD2,SPAG1,OPTN,SOCS3,GALNT3,SERPINA1,UAP1,NMI,SIPA1L1,C1orf21,SPTBN5,IRF7,RBM43,SERPINB1,SEMA3A,JAK3,COBL,FAM134B |
| 3.975e-04 | -7.83 | SCN5A (sodium channel, voltage gated, type V alpha subunit) | protein interactions | 6331 | 20 | 10 | 16036 | 2547 |
SNTA1,SCN5A,RGS3,SNTB2,CALM1,DLG1,CBL,SNTB1,DLG3,WWP2 |
| 4.005e-04 | -7.82 | fibroblastic | COSMIC cancer mutations | fibroblastic | 18 | 9 | 17775 | 2585 |
CDKN2C,RB1,NF2,AKT1,PTEN,SMO,PIK3CA,ERBB2,EGFR |
| 4.033e-04 | -7.82 | GAL_LEUKEMIC_STEM_CELL_DN | MSigDB lists | GAL_LEUKEMIC_STEM_CELL_DN | 236 | 54 | 17758 | 2588 |
MRC2,LGALS3,GALNT12,HAL,OSGIN2,CDCA8,COL18A1,NDRG2,CCNB1,PHLDA1,ITGA2B,SIRPA,SAC3D1,TOP2A,TYMP,SCNN1A,CCNA2,SLC16A6,PASK,CAPG,ADCK2,BUB1,IGFBP2,MINPP1,DLX4,GM2A,CYP1B1,HMMR,PLK1,ZWINT,CENPA,COL6A2,ERMAP,KIF20A,NR4A1,CDC20,TEP1,KLK6,NUSAP1,TNS1,YES1,CDC25C,CDK1,MOSPD3,SLC6A6,SERPINA1,HPSE,SECTM1,E2F1,MAPK13,CCNB2,E2F8,ESPL1,MELK |
| 4.036e-04 | -7.81 | AMPK signaling pathway | KEGG pathways | hsa04152 | 123 | 34 | 6908 | 1076 |
PRKAA2,ACACB,SLC2A4,TBC1D1,CAMKK1,SCD5,PRKAA1,PPP2R3A,CCND1,CCNA2,IGF1R,PFKL,PIK3CA,GYS1,PIK3CD,MAP3K7,SIRT1,AKT1,PFKFB2,PIK3R1,STRADB,LEPR,RHEB,CRTC2,IRS2,TSC1,INSR,PRKAG2,PPP2R5A,CAB39,PPP2R3C,ADIPOR1,PPP2R2D,PPP2R5D |
| 4.036e-04 | -7.81 | AMPK signaling pathway | KEGG pathways | ko04152 | 123 | 34 | 6908 | 1076 |
PRKAA2,ACACB,SLC2A4,TBC1D1,CAMKK1,SCD5,PRKAA1,PPP2R3A,CCND1,CCNA2,IGF1R,PFKL,PIK3CA,GYS1,PIK3CD,MAP3K7,SIRT1,AKT1,PFKFB2,PIK3R1,STRADB,LEPR,RHEB,CRTC2,IRS2,TSC1,INSR,PRKAG2,PPP2R5A,CAB39,PPP2R3C,ADIPOR1,PPP2R2D,PPP2R5D |
| 4.041e-04 | -7.81 | SANSOM_APC_TARGETS_DN | MSigDB lists | SANSOM_APC_TARGETS_DN | 353 | 75 | 17758 | 2588 |
CASP3,PAPSS2,GNPDA1,CPT2,INPP5D,CD82,DGKA,COL18A1,IL18,GALM,CNTROB,MGST2,SEPT4,MOCS1,CHST2,SDF4,ATP6V0B,CYP2S1,DDHD2,TAX1BP3,PIK3CD,MYH14,PTPRE,CDKN2D,SULT2B1,S100A13,GPX4,SLC5A11,PLEKHO1,TEP1,SLC11A2,ARHGDIB,ATP1B1,MCFD2,CLCN2,CYP4F3,ABR,SEC14L2,TRIM47,CHPT1,RRAGD,PCSK5,RUNX2,PCOLCE,COL4A5,MERTK,DNAJB9,SIRPA,GNS,RAC2,ITGA3,MLPH,ICAM5,CD22,CD70,ABCD1,LPGAT1,NUB1,PPARA,CYFIP2,FAM109A,NPDC1,TP53INP2,GNA11,CYB5A,FAS,CNTNAP1,HLA-B,TMEM50B,CD8A,CASP7,SLC4A4,TOB1,IRF1,XDH |
| 4.041e-04 | -7.81 | autonomic_ganglia-adrenal_gland-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-adrenal_gland-neuroblastoma | 29 | 12 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,EGFR |
| 4.051e-04 | -7.81 | negative regulation of apoptotic signaling pathway | biological process | GO:2001234 | 199 | 48 | 16441 | 2455 |
GCLM,PINK1,BMF,ACVR1,LGALS3,ITGA6,SOD2,PSMD10,TGFBR1,BCL2L1,GSTP1,ICAM1,LMNA,IER3,CTNNB1,DAPK1,BAX,TMBIM6,CTTN,MAP3K7,FAIM,MAPK7,CDKN2D,TMBIM1,CTH,SIRT1,PPIF,AKT1,FIGNL1,PLAUR,GCLC,STRADB,PELI3,SLC25A5,MAPK8IP1,G2E3,FYN,SCG2,HTT,WFS1,MADD,NR4A2,NRG1,ITGAV,UNC5B,HSPB1,IFI6,ZC3HC1 |
| 4.062e-04 | -7.81 | negative regulation of organelle organization | biological process | GO:0010639 | 290 | 65 | 16441 | 2455 |
GAS2L1,ADD1,PTTG1,ARFGEF1,TP53,BCL2L1,CCNB1,PATL2,HDAC6,APC2,SPTB,PHF1,PICK1,IER3,RPS6KA2,CAPG,VAT1,ESPN,TACSTD2,TWIST1,PLK1,SIRT1,PPIF,BAG4,AKT1,DMTN,CDC20,PIF1,AURKB,CCNF,SLC25A5,TRIM9,MID1IP1,TRIOBP,CHMP4B,SPTBN5,TMOD2,PRKAR1A,PINK1,CKAP2,EPS8,PSMD10,LMNA,CORO1B,BMP7,TBCD,MSH2,NEK2,H2AFY,BUB1,RGCC,NUBP1,KDM3A,PLEKHH2,SWAP70,FGFR2,ARAP1,AURKA,HMGA1,UBE2C,TBC1D4,SHROOM2,CTBP1,ESPL1,JARID2 |
| 4.064e-04 | -7.81 | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | MSigDB lists | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | 209 | 49 | 17758 | 2588 |
MYL9,PPP1R12A,SSH1,IQGAP1,ARHGEF7,ITGA6,MRAS,NCKAP1,PDGFB,APC2,FGF19,ITGA2B,PDGFA,PAK6,RAC2,ITGA3,ITGB8,PAK2,PIK3CA,MYH14,PIK3CD,PPP1CA,IQGAP3,PIKFYVE,F2R,TIAM1,PDGFC,SSH3,RHOA,PIK3R1,PIP4K2C,EZR,DIAPH2,CYFIP2,BCAR1,MYL12A,EGFR,ARHGAP35,FGFR2,ITGA7,LIMK1,FGF18,MYLK,PPP1CB,ITGAV,ARPC2,MYL12B,ARHGEF4,FGD1 |
| 4.070e-04 | -7.81 | KANG_CISPLATIN_RESISTANCE_UP | MSigDB lists | KANG_CISPLATIN_RESISTANCE_UP | 18 | 9 | 17758 | 2588 |
GRN,MDK,LZTFL1,RAC2,FAM46A,IGFBP6,FTH1,MAFF,ZDHHC3 |
| 4.090e-04 | -7.80 | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP | MSigDB lists | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP | 657 | 127 | 17758 | 2588 |
CCNI,KIF3C,ADD1,TUBB4B,GNPDA1,CRYM,CUL1,BLCAP,PSME1,BAIAP3,PLA2G16,CDIPT,SNN,PJA2,ERP29,KBTBD11,CHPF,APLP2,ATP6V0B,EFR3A,P4HB,DPYSL2,DDHD2,PSMC2,AKR1B1,ATRNL1,GOT1,ARNT2,IFIT1,MARCH2,MYRIP,CPE,HSPA2,GPX4,TUBA4A,SOD1,SEC61B,AKT1,DSTN,STAU2,DRAP1,HSPA12A,RNF11,CLSTN1,NFE2L1,SYP,GLO1,BCL7B,ALCAM,OPTN,MAN2A2,MSL1,SLC25A4,PAFAH1B3,PNPLA6,RCAN2,SERPINI1,ITPKA,LTA4H,PSMC1,COBL,MYL12B,CBX7,PRKAR1A,GRN,CD99,BIN1,LASP1,FARP1,HSP90B1,PINK1,ENO2,SERPINE2,PSMD7,PDIA3,PSMD10,TRIB2,COX6C,TIPRL,PDXDC1,TSPAN7,COX7A2,SNTA1,IRAK1,CDK16,RIMS3,ATP5H,RUNDC3B,SORL1,H2AFY,FAM102A,TMBIM6,AHCY,NPTXR,CAMK2G,EPHX1,MOB4,ALDH2,RHOA,PSMB4,PAPD7,TCFL5,MPP1,CAPNS1,NPC2,CYFIP2,PSMA4,RASA1,GNAS,NUCB1,RPL12,SCG2,PRCP,UTP14C,SPINT2,DTX4,SPAG7,PGRMC1,TCEAL4,CABIN1,ACADM,FHL1,ARPC2,CD81,CTBP1,SRSF9,RUSC1 |
| 4.092e-04 | -7.80 | MODULE_120 | MSigDB lists | MODULE_120 | 72 | 22 | 17758 | 2588 |
P2RX4,LTBP1,TNK1,IL15RA,TRIP10,COG2,BIK,COL18A1,CR2,SLC11A2,NKRF,PHLDA1,ZNF212,ARHGAP35,SNTA1,ANK1,IGF1R,PLOD2,MYLK,RAB31,TAX1BP3,SERPINI1 |
| 4.092e-04 | -7.80 | LINDVALL_IMMORTALIZED_BY_TERT_UP | MSigDB lists | LINDVALL_IMMORTALIZED_BY_TERT_UP | 72 | 22 | 17758 | 2588 |
TMTC1,FRMD4A,PAPSS2,VAMP3,PDE5A,NES,KDELR3,CTSZ,SNX9,FZD7,TAPBP,ST5,CALD1,TRIOBP,CD9,MDFIC,HMGA1,FHL1,POMT1,CITED2,ATP2B1,ANXA11 |
| 4.092e-04 | -7.80 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN | 193 | 46 | 17758 | 2588 |
TXN,NFKBIE,NQO1,TRIP10,CD63,TUBB4B,SEC61G,CTSB,SDC4,SOD2,FTH1,BCAP31,LMNA,IER3,ZFYVE16,SPP1,KCNN4,FICD,ARL1,PPME1,ATP13A3,MITF,TUBG1,MANF,PIM1,GM2A,GPX4,ABCC1,CYP1B1,LAMP3,PPIF,DOCK4,TNIP1,STAT4,PIP4K2C,AK4,DUSP4,ALCAM,PTGS2,SLCO4A1,ETS2,MAPK13,ATP1B3,ST3GAL1,PSMC1,MAFF |
| 4.092e-04 | -7.80 | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | 193 | 46 | 17758 | 2588 |
GAS2L1,GRN,EXPH5,ACVR1,TTC39B,SLC16A14,TRIP10,CKAP2,CERCAM,NENF,PLXNA1,CRABP2,DPP8,ITGA2B,EPDR1,IER3,PQLC2,SPIN4,OPN3,DAPK1,SNX16,PIM1,C12orf75,RPGR,FARP2,PCGF5,SHMT1,MLEC,MAPKAPK3,NKAIN1,PIM3,NEURL1B,CD83,DCAF10,TMEM164,SLC6A6,TIMP3,GDE1,PLOD2,TTC12,P4HA2,SLC2A6,NR4A3,PPP2R3C,GLA,ALG2 |
| 4.092e-04 | -7.80 | WANG_CISPLATIN_RESPONSE_AND_XPC_UP | MSigDB lists | WANG_CISPLATIN_RESPONSE_AND_XPC_UP | 193 | 46 | 17758 | 2588 |
ANXA3,MZT1,HSP90B1,CKAP2,FXYD3,ASB9,GATA3,COL18A1,COL4A5,MGST2,TNFSF9,LBR,CDH1,CTSC,KIF14,GPC3,RDH14,CD9,CLDN4,KIF22,IGFBP2,MXD3,MANF,RNASEH2A,MSH6,SMC4,CKS2,SEMA3B,FADS2,HES1,FIGNL1,NPC2,KIF11,CDK1,CYP4F3,PTPRF,SERPINA1,AREG,DCK,DBI,SPINT2,AURKA,PDXK,UBE2C,ZNF502,JARID2 |
| 4.092e-04 | -7.80 | GSE360_DC_VS_MAC_L_DONOVANI_UP | MSigDB lists | GSE360_DC_VS_MAC_L_DONOVANI_UP | 193 | 46 | 17758 | 2588 |
CASP3,CDS2,TXN,PPFIBP2,HMGN3,CTSZ,TP53I11,GSTP1,PDGFA,CA2,CTSC,LYPD3,FBXO7,AKR1B1,ADAM15,AHCY,TLN2,PTPRE,SMYD5,PPP6R1,RBMS2,EPHX1,LAMP3,PCCB,MAPKAPK3,PTPN9,CLSTN1,LITAF,CALCRL,CAPNS1,FXR2,GTF2A2,EGFR,VCP,CD83,BCAR3,IL1R1,TIMP3,CASP7,PSMD3,NFKBIA,NMI,CSTF2,PKD2,KPNA2,MDH1 |
| 4.092e-04 | -7.80 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | 193 | 46 | 17758 | 2588 |
PRSS8,TXN,HSP90B1,AGRN,S100A11,AASS,PSME2,NDRG1,TSC22D3,GMPR,MORF4L2,DUSP5,SPTB,SLC9A3R2,CHST2,ICAM1,IER3,TYMP,PSMD1,CDH1,TIMP1,ANKRD12,TRIM21,IFIT1,MANF,CYP1B1,DUSP1,PLSCR1,MICB,RAPGEF2,SAT1,PTGER4,AK4,RNF19B,LCP1,CD83,STK17A,ENDOD1,PLCH1,SERPINA1,ACVRL1,NFKBIA,DBI,NR4A3,PSMC1,IFI6 |
| 4.100e-04 | -7.80 | gland morphogenesis | biological process | GO:0022612 | 108 | 30 | 16441 | 2455 |
NKX3-1,RPS6KA1,SOX9,ERBB2,EZR,TFAP2C,SCRIB,PLXNA1,DAG1,NFIB,EGFR,ELF3,NCOA3,IGF1R,AREG,TWSG1,FGFR2,CSF1,STAT6,BMP7,SERPINB5,HOXB13,PLXND1,NTN1,SEMA3A,ETV4,SLC12A2,RARG,FOXA1,CAPN1 |
| 4.107e-04 | -7.80 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | biological process | GO:0002479 | 75 | 23 | 16441 | 2455 |
SEC61B,PSMB4,SEC61G,HLA-E,PSME2,HLA-F,PSMD7,TAP1,PDIA3,PSMD10,PSME1,PSMA4,HLA-A,CALR,HLA-B,TAPBP,PSMD1,PSMD3,PSMC2,ITGAV,HLA-C,PSMC1,PSMA5 |
| 4.107e-04 | -7.80 | toll-like receptor 9 signaling pathway | biological process | GO:0034162 | 75 | 23 | 16441 | 2455 |
UNC93B1,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PIK3AP1,PELI2,NFKBIA,NOD2,MAPK11,IRF7,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 4.108e-04 | -7.80 | transport | biological process | GO:0006810 | 3697 | 617 | 16441 | 2455 |
DOC2A,ACACB,ADD1,IBTK,GRIK2,SLC25A13,MCOLN3,CACNA2D2,TRAPPC8,TGOLN2,LGI3,BAIAP3,SYTL4,SNX9,SLC35E4,TP73,CALM2,NAPG,PQLC2,AP1M2,SLC46A1,ATP13A3,DNM2,PIK3CD,TINAGL1,TMEM37,TUBA4A,VPS11,UXT,KDELR3,PRKAR2B,LOXL2,ICMT,RNF19B,ARF4,SLC44A3,ENPP1,PLCG1,DNM1L,LIMK1,ATP7B,TRAF3IP1,NOD2,RNASEL,ARF6,ANXA11,NXT2,SCN5A,NFKBIE,GGA1,SEC61G,RAB23,SLC36A4,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,RIMS3,ATP5H,FBXO7,RANBP1,PCYOX1,CADPS2,CNGA1,PANX2,NUP85,C9orf72,PPP6R1,NAGPA,UFD1L,SLC37A1,KIF20A,MAPKAPK3,ERO1A,CALCRL,PLS1,SRSF5,PCTP,GOLT1A,SFXN5,RHOB,CYB5A,CACHD1,SCARB2,SLC4A4,TIMM8A,HTT,ITPR1,DYSF,OSCP1,NDE1,ARPC2,TRPC3,NUP58,XDH,MTM1,CCDC109B,APOO,C5orf30,MVB12B,PRKACA,APPBP2,CCND1,SCNN1A,ACSL4,ARL4D,RAB27B,SNX10,TMEM9,SCN3A,SNX8,SEC61B,FZD4,VPS4B,HTATIP2,SYP,RAB38,SNX12,PEX5,STX10,CORO1C,SLC9A6,AXL,RGS14,SLC25A30,TTC8,TCAF1,TAOK2,HSP90B1,HABP4,FLOT1,BTN3A1,PDIA3,CTSZ,ANO9,KCNC4,IFT27,SLC25A43,PDIA4,CXCL16,SLC25A45,ANK1,ADD3,SLC27A6,CTSC,FAM160A2,KCNK5,BAX,KLC3,WWP1,TPCN1,S100A6,HCN3,ACBD5,MOB4,LCA5,MFSD2B,PIK3R1,EIF5A2,MRS2,GRIN1,PGBD1,RAB3IP,FAM109A,NEURL1B,RGPD5,LDLRAP1,RPL12,RAB11FIP2,SYT7,SLC35B3,DBI,NR4A3,ARFGAP3,SSNA1,ITGAV,NUP37,CD81,USF2,SRSF9,CYBRD1,UNC93B1,ILDR1,ARFGEF1,F11R,ITPR2,HDAC6,NUP62CL,PDGFB,SUSD2,NUP210,TM9SF2,CTNNB1,RABEP2,ARL1,LMAN2L,SLC44A1,ABCA2,ANO4,SCARA3,TRAM1,S100A13,KCNIP3,CELSR2,STAU2,EZR,ARFRP1,ESYT1,CLCN2,VCP,OPTN,TRIM9,TRAM2,TBC1D17,KCNMB4,WIPI1,RAB11FIP1,KPNA2,PIEZO1,TC2N,PRKAA2,FXYD3,SLC22A31,RACGAP1,RAB6A,NCKAP1,ANO1,PGAP1,SSX2IP,TIMP1,RINL,GATA2,FRAS1,ICAM5,KIF13B,FCHO1,SLC30A6,EXOC8,SELK,ABCC1,STRADB,SCRIB,EIF2AK1,ZDHHC3,NMT2,MAPKAPK2,MFSD2A,SLC2A6,ZDHHC7,LTBP2,ATP1B3,PLD1,NIPA1,KCNAB3,UPF3B,TP53,P2RX7,SLC7A2,EMP2,BCAP31,SYTL2,SDF4,TTC21B,PDGFA,ATP6V0B,SRPX,PLCG2,BCL6,ZDHHC23,SCN2A,LMAN1,GM2A,PPIF,CLCN3,AKT1,ACO1,DAG1,ATP13A2,TAPBP,ATP1A1,MAOA,CHMP4B,SYT13,RPL22,COPG1,ARFGEF3,BIN1,MFSD14B,PACSIN2,GOLIM4,TRAPPC10,CD63,GABRG2,CRABP2,AIP,VPS26A,SLC9A2,M6PR,ZDHHC21,CDK16,SLC35B4,SGK1,ABCD1,CPLX1,SYK,SLC45A3,CAMK2G,ATP2B1,P2RX4,HES1,FBLN5,PPARA,PRICKLE1,COL7A1,AKAP3,BBS2,MAPK8IP1,SCRN2,SERPINA1,SCG2,TMC5,PKD2,SPCS3,NDFIP1,TBC1D4,ARHGEF9,LAMP1,SLC35D2,TSC22D3,ATP8A1,KLC2,TAP1,GATA3,SLC20A1,RIC1,NCS1,SLC9A7,PICK1,CTGF,STIM1,ELMO2,OSBPL3,STEAP2,PIK3CA,SERINC2,KCNS3,SNX16,MARCH2,PACSIN1,TFG,XKR8,LAMP2,ORAI2,BNIP3L,SLC35C1,KIF13A,SLC17A5,MCFD2,SLC25A5,SPNS3,RAB2B,SFXN1,SLC25A4,AREG,GNPTAB,SARAF,SLC31A2,F2RL1,RTN3,MRC2,INPPL1,SLC25A27,NDUFA4,SLC1A3,APBA1,CALR,DOPEY2,SNX18,NECAB3,SLC16A6,RPL39,SORL1,CACNA1D,PIKFYVE,SYTL3,RIMS2,TMED2,TRAK2,KCNJ12,GCC2,PMPCB,MFI2,CALM1,ANO6,NPC2,ATP8B3,CYFIP2,STX3,GABRD,AP1AR,SLCO4A1,PRKAG2,CSNK1G1,WDR19,ZDHHC20,SLC4A3,PLIN3,HOOK1,NRBP1,EHD1,PKD1L2,PLA2G4A,MFSD3,KIF3C,SLC2A4,GPR107,TRIP10,RALBP1,ATP2C2,FTH1,CD274,BCL2L1,DDR1,TMPRSS4,SLC25A35,ZFYVE9,CNNM4,TNPO2,CDKN1B,IFIT1,OSBPL7,TBC1D10B,ATG4D,MYO5B,SLC5A11,SEC23A,COG2,DMTN,COX11,KIF1C,SLC11A2,ATP1B1,ITPR3,ATP10D,OSBPL2,FYN,DDOST,SLC27A1,RAB29,PRKAR1A,DENND5B,SLC16A14,SLC41A1,ATP9A,ARL4C,PLD2,CYB561,LGALS3BP,COX7A2,CKAP5,SLC25A36,PPP1R10,CD9,SGK3,ATP8B1,SLC44A2,TTPA,SLC16A5,NCOA2,CASK,ZC3H11A,DENND1B,FURIN,VAMP3,PARP4,YES1,CPTP,GPLD1,CRTC2,MAMDC4,CTNS,SEC14L4,FGFR2,SLC25A40,RIN3,ABCB1,GRIN2D,ARSB,SLC25A38,ESYT2,EXPH5,FAF2,TMEM184B,CRYM,CPT2,UBE2Q1,CACNB4,DNER,SLC8B1,ERP29,TMC1,SH3KBP1,ABCD4,MAGOHB,ZFYVE16,RAB15,DPYSL2,TRPC1,RAB20,RP2,CTTN,SLC39A10,MYRIP,RASGRP1,SOD1,ACBD3,ADRBK2,TCN2,EDNRA,SEC14L2,UEVLD,KCNK1,APBA2,PCSK5,GRN,LASP1,ARAP3,BVES,PEX6,ABCG2,ATP6V1E2,CALM3,CA2,KCNN4,PRKCI,FXYD5,SRP54,SLC12A2,GAD1,KDELR1,SNX7,FBXO8,BTN3A2,STEAP1,MFSD7,GNAS,TSC1,SLC6A6,TMEM30A,NFKBIA,SH3BP4,RAB31,CTSA,PITPNA,SHROOM2,JAK3,APOL2,TOB1,SNX30,DRD1,DYNLRB1,SLC25A24,SORBS1,SLC2A8,ABCG4,MICALL2,SLC25A48,SVBP,KIF14,ZDHHC12,FABP6,RPN2,STEAP3,F2R,UPF3A,CHP1,SOAT1,SLC39A8,OSTM1,AP5M1,ALDH5A1,PEX2,SPTBN5,ABCA1,ANXA3,SORT1,SH3D19,LRP4,RBP7,ITGA2B,HMGXB4,TMEM63A,KIF5B,SNX13,MLPH,ADRBK1,ADORA1,LLGL2,RRBP1,ZDHHC13,TRIM3,SLC35A1,RPGR,MYO5A,SYPL1,RAB3B,MAP1B,ARRB1,SLC18B1,MCUR1,ATP6V1C1,CEP41,RAB3IL1,ABCG1,SNPH |
| 4.121e-04 | -7.79 | squamous_cell_carcinoma | COSMIC cancer mutations | squamous_cell_carcinoma | 17441 | 2557 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,HEXB,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,LYPD5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,IL10RB,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,UXT,KDELR3,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,MID1IP1,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,ZCCHC17,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,GOLT1A,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,GDF11,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,TAX1BP3,ZNF365,MYT1,SNX8,ERMP1,C6orf1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,GTF2A2,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,BIK,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,BEX2,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,KLC3,FAM102A,IGFBP2,CASD1,MED22,ACBD5,PVRL4,TACC1,DUSP23,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,HCP5,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,PHOSPHO1,NDRG2,F11R,NENF,MGAT5B,SLC9A3R2,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,SMAGP,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,B4GALNT1,TNS3,TIMP1,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,SELK,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,OTUD6B,PHLPP2,NLRC5,PLD1,AKIP1,SEMA3A,CCNB2,CDAN1,USP43,HOXB7,TMX4,RHPN2,PCBP1,BCAP31,IER3,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,ZNF628,IDE,PTPRJ,MAOA,CHMP4B,XRCC3,IRF7,SYT13,ZMAT1,PINK1,CDH22,TAB3,KLHL13,GNAL,MCTP2,CDCA8,GTF3A,H1FX,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,CPLX1,TSPAN13,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NEIL3,NIPSNAP3A,PTGES,HIPK3,ZBTB33,PKIA,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,TMEM86B,C1orf198,PSME1,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,HYLS1,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,CDKN1C,TBC1D1,TMEM55B,TXNDC9,PSIP1,SH3RF2,C9orf69,DOPEY2,LYPD3,BHLHE41,AIM1,PPP4R1,MSH2,PRKG1,TMEM51,ADCK2,CACNA1D,C8orf58,SYTL3,GPR161,TRAK2,PIGC,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,CDK18,SAMD8,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,SULT2B1,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,CBL,B3GALNT2,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,CCDC149,TRIOBP,ZNF704,CBX7,MAMDC2,IGFBP6,DEPDC1,HAPLN3,EPS8,HERC5,EFHD2,PLD2,FBXO6,EFNB1,FGF19,COX7A2,WWP2,SCML1,SLC25A36,RASSF8,E2F7,TMEM87B,GNB5,RNF128,CD9,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ALDH2,ARHGEF28,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,RIN3,TBX18,ERAP1,RABL6,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CASC4,CDKL5,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,CALM3,PM20D2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,GAD1,ETV7,SNED1,SNX7,MDFI,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,TOB1,RARG,AFAP1,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,ZNF687,ARTN,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,CKS2,SOAT1,RFK,MRPS35,GLO1,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,SECTM1,TLE1,SPTBN5,MAD2L1BP,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,NTAN1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,FIBCD1,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,KLK10,IL15RA,TRIM5,DNAJC3,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,AP1M2,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,ODF2L,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,CAMK2N2,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,ARF6,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,SRSF5,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,TRPC3,ZNF502,EGLN1,CCDC109B,TMSB15A,ACTR8,ETNK1,RGS20,PRSS22,IL13RA1,NUF2,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,CDKN2D,TMEM9,SCN3A,RNF169,ENPP4,CAMSAP3,NRBF2,FZD4,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,RGS14,ARNT,TAOK2,TNRC6C,NKX3-1,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,ARHGEF40,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,CXCL16,ADD3,SLC27A6,ARSG,FAM160A2,KCNK5,MCF2L,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,TMX1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,CCDC6,ACVRL1,NR1D2,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,TP53I11,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,ELF5,RGS5,ANO4,TRAM1,DDX59,NEB,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,FAM212B,ANLN,CLCN2,LHFPL2,RHEB,PLEKHB1,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,HLA-F,ZCCHC24,ASAH1,DOCK11,PGAP1,BMP2,KIAA0895,SPIN4,GATA2,EXOC8,MDFIC,PLCB2,ALDH3A2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,H1F0,CSF1,ATP1B3,CTBP1,FAM45A,KCNAB3,AVPI1,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,ABRACL,ATP6V0B,N4BP3,GYS1,EGLN3,FAR1,SIRT1,TMTC1,CDC20,DUOX1,ATP1A1,RTN4RL1,PRRT4,PSMD3,C1orf43,RPL22,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,TM2D2,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,PPP2R3A,SLC9A2,SIRPA,CEP97,BUB1,HEXIM2,FAIM,SLC45A3,CAMK2G,IGDCC4,MLEC,IFITM3,NR3C1,CRB3,AMFR,LITAF,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,TWSG1,ZNF214,NAT1,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,NDFIP1,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,IQCD,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,SNTB2,PBK,HSPA12A,CASP9,TNS1,SLC17A5,GALNT7,PIF1,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,HLF,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,EIF4EBP2,TMEM8B,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,CALB2,DGKQ,ADO,SLC25A27,C6orf106,KIF23,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,CTPS1,OPN3,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,FAM69A,EPB41L5,DDB2,PMPCB,B3GNT7,ZNF84,MMD,KIAA1841,MICB,AMER1,PIP4K2C,FAM133B,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,TCEAL4,SLC4A3,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,PLA2G4A,ELK4,FRMPD3,TRIP10,TMEM217,S100A11,RPS6KA1,CAST,SUZ12,IQGAP1,RNF182,EGR3,SNN,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,FICD,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,TBC1D10B,GPX4,SLC5A11,TEP1,PRKCQ,BCL7B,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TEAD3,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,CNPY3,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,VAMP3,FURIN,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,HEBP1,CAMKK1,FLYWCH2,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,ABCD4,MAGOHB,NKAIN3,C7orf49,LRRC6,TSPAN6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,TRIM45,IARS2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,EBF4,SIMC1,HP1BP3,PARD3B,GYLTL1B,FBXO8,HMG20B,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,SPC25,ABCG4,TDRKH,ZMYND10,ARHGEF16,SS18,SLC25A48,KCTD15,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,GCA,SLC39A8,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,CKS1B,BRD7,RAB3B,PHLDB3,OGDHL,LRRC66,MBNL3,SPAG1,C2orf70,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,RNF26,WBP4,TIAM1,TIPARP,ANKRD9,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,RNF19B,GINS4,ARF4,ENPP1,CARHSP1,PLCG1,BOLA3,CELF5,ATP7B,TRAF3IP1,FAM114A1,HDAC1,RNASEL,ITPKA,HSPB1,NXT2,SCN5A,COX6C,CCDC64B,HPCAL4,RABGGTA,TFAP4,MARCH8,FLII,PAIP2B,FLRT3,RIMS3,MEGF8,ATP5H,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,ALPK1,FAM84B,ZMYM1,MYLIP,KANK3,DGKG,ULBP2,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,C11orf45,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,CBX5,RUSC1,ADAMTS16,DOCK9,TPRN,NQO1,LFNG,CD82,PTTG1,RHBDL3,APOO,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,SZRD1,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,SAT1,EBF2,GIGYF1,GABARAPL1,SPIN3,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,SGPL1,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,CST3,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,AK4,C4orf27,LDLRAP1,RPL12,PROM1,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,ARL1,IL6ST,PAPSS1,PSMC2,MITF,SLC44A1,SCARA3,PLK1,KRT80,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,AGPAT2,ZNF367,TXNRD3NB,KPNA2,TTC39C,MYL12B,TC2N,HS6ST3,RRAGD,RMND5A,PRSS8,LGALS3,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,HES2,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,ZNF320,MGAT4B,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,P4HA3,SLC2A6,ZDHHC7,ZDBF2,RAD21,CTDSPL,TP53,P2RX7,BAHD1,STIL,PRR7,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,VAT1,ESPN,NOTCH3,LMAN1,ERLEC1,KIAA0040,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,FAM134B,CTDSP1,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,HMGN3,GDF15,AIP,LBR,VPS26A,IL22RA1,PARM1,FZD6,SH2D4A,NRP2,M6PR,CD109,C16orf74,ALPP,CDK16,FAM63A,GTF2F2,TFAP2A,SGK1,TRIM21,HMGCL,SYK,WBP5,LRRC24,P2RX4,HES1,MOSPD2,HMGN5,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,BBS2,TXNDC11,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,SMTNL2,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,NANS,SEPT4,OAT,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,TACSTD2,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,MESDC2,CALR,RALGPS2,ZNRF2,RPL39,VASN,DAPK1,TPST1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,NPC2,ANTXR1,NFIB,PDE11A,NT5C2,AP1AR,FAM64A,FAAH,PELI2,ZDHHC20,C1orf21,MATN2,ARAP1,FAM83D,MPP2,CABIN1,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,TCTN2,GPR107,CAPN12,REPS2,DLGAP5,ST14,NDRG1,RALBP1,CERCAM,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,FLT3,DDR1,ART5,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,PRR15,COBL,PRKAR1A,IER5L,PLSCR4,SLC41A1,CENPI,CBLL1,PBX3,NES,DNAH3,HLA-A,CKAP5,FUT8,FJX1,DRAM1,ERBB3,MSH6,TGIF1,ZWINT,B3GNT2,LONRF3,PAPD7,TCFL5,FBXO9,YES1,GRTP1,AIF1L,FOS,CRTC2,CDK5RAP1,TIMP3,SEC14L4,ABCB1,WDR91,FZD5,MELK,UGT8,COMMD5,MAP1LC3B,ERP29,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,NLRP4,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,CAB39,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,PYROXD2,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,MTMR10,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,COL16A1,APOL2,DRD1,CCNE2,LMO7,HDAC11,SOD2,OSR2,EXT2,MXD1,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,EBAG9,SEPHS1,PTPRU,C3orf52,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SH3D19,SHPRH,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,HMGXB4,ITGA2B,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,TAF1B,ADRBK1,LLGL2,A4GALT,ZDHHC13,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,TCEAL8,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,DOC2A,TRIM24,ADD1,MRPS15,AASS,XIAP,MMADHC,FBXO2,DHX8,LGI3,CA8,KIF26A,EPDR1,CALM2,TP73,WEE1,PSMD1,PQLC2,ARHGAP42,RGS12,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,MANF,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,SPRTN,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,NAGPA,UFD1L,SLC37A1,CALCRL,PLS1,MEST,TP53INP2,SPTLC2,RHOB,PTPRF,SCARB2,TIMM8A,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,GRHL2,PAPSS2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SP100,DACT1,ARL4D,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,GEN1,TTC8,GALK1,FARP1,PDIA3,PKN1,NUCB2,GSTP1,KCNC4,TIPRL,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ADAM15,ECI2,MAPK11,NKAPP1,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,FAM160A1,CTNNAL1,BCL9,GRIN1,MYEOV,NEURL1B,FAM109A,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,HMGA1,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,SUDS3,MCCC1,NDC80,CDIPT,SDC1,PIGL,PCNA,CNTRL,LMAN2L,DDHD2,DUSP10,TNFRSF18,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,TNFAIP8L1,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,PIEZO1,TTC9,EPB41L4A,GLCCI1,FAM89A,BMF,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,DHRS3,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,ANKRD29,MAPKAPK2,COQ10A,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SRR,MINPP1,SCN2A,DVL2,GM2A,CTH,CPD,MBP,FIGNL1,COQ10B,MYL12A,MYPOP,DNAJC10,C19orf66,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,GABRG2,SELL,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,SLC35B4,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CCDC34,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,ZMYND19,CDCA7L,NMI,CLIP4,PKD2,ACADM,SAT2,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,PLA2G16,FAM101B,ELMOD2,CENPN,CHST2,NCS1,ELMO2,PRICKLE3,IQCE,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,MCFD2,SAV1,SLC25A5,ZFAND5,TP53I3,ULK2,SGPP1,AHRR,FAM177A1,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,ISYNA1,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,TBC1D8B,B9D2,ANO6,PTPRH,TMEM133,KCTD20,VEZT,PKM,FBXO10,GLT8D2,STX3,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,EFNA1,MAP3K5,SLC2A4,CEP70,ARMCX3,NLRX1,BROX,IRX4,KCTD12,CD274,AIFM2,MNS1,CYHR1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,PRDM11,CMTM7,EPHA10,ZNF641,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,RND1,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,TRIM62,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CASP3,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,ATL1,SOD1,FOPNL,RNF165,MRPS18A,MRPS36,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,DHRS13,CCDC74B,ADIPOR1,LEMD1,APBA2,PSMC1,MIIP,GRN,FAM213B,ELOVL7,ATP6V1E2,SAMD9,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,RFX5,KNTC1,ACAD8,NCEH1,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,SLC2A8,PSME2,MORC4,GMPR,PATL2,MICALL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,KCTD2,MAP3K6,BHLHB9,PEX2,OVOL1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,MXD3,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,PRCP,DHRS2,HNRNPH2,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 4.123e-04 | -7.79 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | MSigDB lists | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 29 | 12 | 17758 | 2588 |
MYL9,RAC2,RHOA,ARHGEF11,SEMA4D,LIMK1,ERBB2,MYH14,MYL12B,RHOB,RND1,ARHGAP35 |
| 4.123e-04 | -7.79 | DORN_ADENOVIRUS_INFECTION_12HR_UP | MSigDB lists | DORN_ADENOVIRUS_INFECTION_12HR_UP | 29 | 12 | 17758 | 2588 |
BCAR3,DDX58,MMP15,CYR61,RND3,NR4A1,PLK2,TSC22D3,SERPINB5,IFIT1,EGR3,NFKB2 |
| 4.123e-04 | -7.79 | Kinesin | pfam domains | PF00225 | 44 | 16 | 16629 | 2504 |
KIF3C,KIF20A,KIFC2,KIF23,KIF1C,KIF13A,KIF20B,KIF2C,KIF11,KIF26A,KIF5B,KIF13B,KIF14,KIF22,CENPE,KIF12 |
| 4.134e-04 | -7.79 | Kinesin_motor_CS | interpro domains | IPR019821 | 41 | 15 | 18293 | 2672 |
KIF5B,KIF3C,KIF20A,KIFC2,KIF14,KIF13B,KIF23,KIF1C,KIF22,KIF13A,KIF20B,KIF2C,CENPE,KIF12,KIF11 |
| 4.142e-04 | -7.79 | BIRC5 (baculoviral IAP repeat containing 5) | protein interactions | 332 | 42 | 16 | 16036 | 2547 |
CASP3,UFD1L,CASP9,CDCA8,XIAP,AURKB,HDAC6,AIP,CDK1,RASA1,RB1,CASP7,E2F1,AURKA,USF2,F2RL1 |
| 4.150e-04 | -7.79 | cutaneous_T_cell_lymphoma | COSMIC cancer mutations | cutaneous_T_cell_lymphoma | 33 | 13 | 17775 | 2585 |
RB1,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,JAK3,EGFR |
| 4.150e-04 | -7.79 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-cutaneous_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-cutaneous_T_cell_lymphoma | 33 | 13 | 17775 | 2585 |
RB1,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,JAK3,EGFR |
| 4.151e-04 | -7.79 | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta) | protein interactions | 7529 | 341 | 78 | 16036 | 2547 |
LMO7,TNK1,SORBS1,TUBB4B,CAMKK1,RPS6KA1,KLC2,TESK2,PKP2,UHRF1BP1L,CDK14,WEE1,SIPA1L2,RGS3,FRYL,ZFP36,OSBPL3,CDKN1B,MAP3K3,DOCK4,ING1,MARK1,PFKFB2,DMTN,KIF1C,CBL,CDC25C,GIGYF1,VCP,OPTN,IRS2,MPRIP,SHROOM3,STK38,KIAA1804,RAB11FIP1,TANC2,REEP4,HSPB1,PPP2R5D,CBX4,CDK17,TBC1D1,DCAF7,FRMD6,KIF23,RACGAP1,NCKAP1,DOCK11,KIF5B,IGF1R,RALGPS2,CDK16,KIF13B,PAK2,BAX,DAPK1,ACTA2,MAPK7,RASGRF1,HES1,TESK1,PLEKHA7,CYFIP2,EGFR,CRTC2,TSC1,INSR,CCDC6,RAB11FIP2,DCUN1D1,PPM1H,ARRB1,CDK18,GEM,WDR62,TBC1D4,USP43 |
| 4.163e-04 | -7.78 | HLA-E (major histocompatibility complex, class I, E) | protein interactions | 3133 | 50 | 18 | 16036 | 2547 |
NEK4,TCTN2,HLA-E,GALNT12,HLA-F,ITGA6,XRCC6BP1,HLA-A,MAN2A2,CALR,HLA-B,CD8A,MADD,PPP1R16A,EPHB4,HLA-C,MGAT5,TMEM131 |
| 4.181e-04 | -7.78 | KEGG_INOSITOL_PHOSPHATE_METABOLISM | MSigDB lists | KEGG_INOSITOL_PHOSPHATE_METABOLISM | 54 | 18 | 17758 | 2588 |
INPPL1,ALDH6A1,PIP4K2C,ISYNA1,CDIPT,INPP5E,PLCG1,PTEN,OCRL,PLCG2,PIK3CA,INPP4B,PIK3C2B,PIK3CD,PIKFYVE,ITPKA,MINPP1,PLCB2 |
| 4.181e-04 | -7.78 | activation of immune response | biological process | GO:0002253 | 435 | 91 | 16441 | 2455 |
UNC93B1,TRIM5,INPP5D,RPS6KA1,PSME2,CUL1,GATA3,PSME1,ITPR2,PRKACA,CACNB4,CALM2,CD46,PSMD1,RPS6KA2,ELMO2,PSMC2,PLCG2,PIK3CA,PDE4D,PIK3CD,NFKB2,SCARA3,LGMN,CD55,RIPK2,TNIP1,ITCH,CR2,PRKCQ,ITPR3,DUSP4,PLCG1,PTPRJ,FYN,PSMD3,LIMK1,NOD2,IRF7,PSMC1,PPP2R5D,DDX58,HSP90B1,TAB3,THEMIS2,CTSB,PSMD7,CALM3,BTN3A1,PSMD10,PLD2,NCKAP1,TEC,VASP,IRAK1,PTEN,PIK3AP1,PAK2,BAX,MAPK11,MAPK7,MAP3K7,CNPY3,SYK,PSMA5,PSMB4,MAPKAPK3,MICB,CALM1,PIK3R1,RGCC,YES1,CYFIP2,ELK1,FOS,BCAR1,PSMA4,GPLD1,TXK,BCL10,MAPKAPK2,CTSL,PELI2,NFKBIA,ITPR1,NR4A3,UBE2D2,ARPC2,IFIH1,RPS6KA3,TMEM173 |
| 4.186e-04 | -7.78 | FRS2 (fibroblast growth factor receptor substrate 2) | protein interactions | 10818 | 27 | 12 | 16036 | 2547 |
PTPRF,INSR,SORBS1,FGFR2,RET,PRKCI,FLOT1,CBL,DDR1,SPRY2,GAB1,RND1 |
| 4.191e-04 | -7.78 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN | 37 | 14 | 17758 | 2588 |
RASGRF1,PDGFC,CTHRC1,CASP7,RBL1,PLOD2,DPYSL2,CAPG,FHL2,CKS1B,POLD3,UBE2C,LTBP3,CDK1 |
| 4.198e-04 | -7.78 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | 146 | 37 | 17758 | 2588 |
DDX58,HERC5,GDF15,ISYNA1,HERC6,DHRS3,FLT3,LTBP3,LGALS3BP,CHST2,MECOM,SLC27A6,CDH1,IFIT1,OAS3,RAB27B,F2R,GAD1,MX1,PRSS23,USP18,FHL2,PRKAR2B,IFIT3,IRX3,PTGS2,HOXA9,ATP7B,AMMECR1,FGF18,STAT1,ABCB1,IRF7,NR4A2,HS3ST3B1,IFIH1,IFI6 |
| 4.201e-04 | -7.77 | negative regulation of epithelial cell proliferation | biological process | GO:0050680 | 113 | 31 | 16441 | 2455 |
CASK,NKX3-1,CDKN1C,WNT10B,SOX9,RGCC,GATA3,TGFBR1,RUNX3,EAF2,VASH1,SAV1,NFIB,CD109,RB1,PDCD10,TGFBR3,FGFR2,PTEN,SCG2,ACVRL1,GPC3,CTSV,PEX2,DLG1,STAT1,CDKN1B,DAB2IP,KLF9,ETV4,XDH |
| 4.207e-04 | -7.77 | Glycosphingolipid biosynthesis - globo series | KEGG pathways | hsa00603 | 14 | 8 | 6908 | 1076 |
B3GALNT1,FUT2,A4GALT,HEXB,FUT1,GLA,ST3GAL1,NAGA |
| 4.207e-04 | -7.77 | Glycosphingolipid biosynthesis - globo series | KEGG pathways | ko00603 | 14 | 8 | 6908 | 1076 |
B3GALNT1,FUT2,A4GALT,HEXB,FUT1,GLA,ST3GAL1,NAGA |
| 4.213e-04 | -7.77 | FERM_N | interpro domains | IPR018979 | 29 | 12 | 18293 | 2672 |
EPB41L5,FARP1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 4.234e-04 | -7.77 | negative regulation of metabolic process | biological process | GO:0009892 | 2618 | 448 | 16441 | 2455 |
ACACB,TXN,PPP4R4,TRIM24,LGR4,IBTK,TSC22D3,DNAJC3,XIAP,GATA3,PSME1,MORF4L2,CCNB1,BARD1,RIC1,PHF1,TP73,CALM2,CDKN2C,PSMD1,CTGF,ZFP36,CABP1,RGS3,FOSB,IRF2,CRY2,ZBTB18,TIPARP,APOBEC3G,SMARCA2,TNIP1,PBK,UXT,CDYL,CDA,TFAP2C,AGO4,PRKAR2B,LOXL2,PIF1,AURKB,PPP1R14C,POR,AHRR,PIAS3,ENPP1,CAMK2N2,LIMK1,TRAF3IP1,PPP2R4,PRDM5,NOD2,HDAC1,SERPINB6,EIF4EBP2,SERPINI1,SPRY4,HSPB1,F2RL1,E2F8,LZTS1,INPPL1,CDKN1C,SOX9,PRKAA1,RAB23,SH3RF2,MECOM,ELF3,MARCH8,TFAP4,CALR,PAIP2B,BHLHE41,FBXO7,MSH2,DAPK1,SORL1,MAPK7,DLX4,NUP85,TMED2,SOCS5,QSOX1,SALL4,CALM1,FHL2,WHSC1,EPHA1,ILK,KDM3A,PSMA4,NFIB,PLIN5,FAS,AP1AR,PRKAG2,ETS2,HTT,SEMA4D,NAB2,PIAS2,SFMBT1,NR4A2,STK39,CABIN1,EFNA1,PER3,CBX5,SERPINB1,NUP58,RPS6KA3,XDH,EGLN1,IRF1,ELK4,SPRED1,TCF25,NQO1,S100A11,THRA,INPP5D,RPS6KA1,CAST,SUZ12,IQGAP1,PTTG1,WDTC1,BCL2L1,CCND1,CD46,APLP2,SP100,DACT1,FICD,CDKN1B,DAB2IP,PDE4D,IFIT1,DLG3,CDKN2D,FLOT2,MYT1,NR2C1,TMBIM1,RNF169,CAMSAP3,APOBEC3D,DMTN,DRAP1,COX11,RAD17,PKMYT1,H2AFV,SNX12,NFIX,IRS2,FYN,PPP2R5A,CORO1C,WFS1,WWTR1,STAT1,SLC27A1,KLF5,NRG1,RGS14,CBX7,PRKAR1A,FARP1,TNRC6C,NKX3-1,DEPDC1,TRAF2,NES,APOBEC3H,PKN1,ZNF219,GSTP1,TIPRL,FGF19,SIX4,WWP2,CTNNBIP1,SNTA1,E2F7,PDCD10,ITGB8,RNF128,IRAK1,PTEN,PPP1R10,GPC3,CST3,BAX,ATP8B1,TMBIM6,WWP1,ERCC2,CITED2,CNOT6L,RAG1,GFI1,SPRY2,TRIM62,NCOA2,CRTAP,MSH6,TGIF1,RAPGEF2,FURIN,GPLD1,PITX2,CDK5RAP1,TIMP3,FGFR2,ACVRL1,NR1D2,PRDX3,TBX18,NR4A3,SERPINB5,ITGAV,GPER1,HMGA1,LRRK1,NUP37,OSR1,SHOX2,CPEB2,SRSF9,JARID2,CCNC,SIGIRR,CASP3,FAF2,ST13,CRYM,CNOT8,SUDS3,ARFGEF1,LMCD1,NDRG2,F11R,HDAC6,PDGFB,ERP29,NUP210,CTNNB1,SIVA1,PSMC2,PASK,MITF,DLG1,DUSP10,MYBL1,CYP1B1,PLK1,THRB,SOD1,CD55,KCNIP3,CXXC5,TRIM8,ASXL1,ITCH,CBX6,EZR,PRKRA,OPTN,EDNRA,NEIL1,KLF12,PRKCDBP,KLF11,GLA,PSMC1,RUNX2,LMTK3,PPP1R2,PPP1R12A,SERPINE2,DNAJB2,UBASH3B,PDCL,PSMD7,CALM3,SORBS3,HES2,FBLN1,DUSP5,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,FNIP1,MDFIC,PIM1,RFX5,ETV7,PSMA5,MDFI,ELK3,HMG20B,EIF2AK1,RANBP9,EGFR,CDK5R1,NUDT16,TSC1,PLPP3,NFKBIA,SH3BP4,NLRC5,YOD1,CDAN1,JAK3,TOB1,CTBP1,IFI6,RARG,DRD1,GAS2L1,NF2,FOXM1,PSME2,CTDSPL,TP53,P2RX7,TDRKH,OSR2,BAHD1,PATL2,MXD1,SYTL2,PER2,IER3,PDGFA,SAP130,SVBP,SETDB2,PPME1,BCL6,SMO,TWIST1,NOTCH3,NFKB2,CTDSP2,CHP1,PPIF,SIRT1,TIMP2,ERLEC1,BAG4,AKT1,CDC20,ERBB2IP,DUSP4,DAG1,C3orf33,ARHGAP35,SOCS3,HSF4,MYPOP,DNAJC10,IDE,ATP1A1,PTPRJ,RBL1,PSMD3,STAT6,STK38,PEX2,OVOL1,PTBP3,TLE1,CHMP4B,IRF7,CBX4,CTDSP1,ARFGEF3,GLIS3,ANXA3,PINK1,SORT1,CPEB4,DAP,SERPINB9,PSMD10,AES,NKRF,TRIB2,AIP,FZD6,SH2D4A,HDAC9,CD109,IRF2BPL,FOXP2,ADORA1,TAF1B,BMP7,UBE2J1,TFAP2A,H2AFY,BRD7,TRIM21,BUB1,KANK2,HEXIM2,MXD3,IQGAP3,DUSP1,NFE2L3,HES1,RHOA,PSMB4,WNT10B,IFITM3,PLAUR,GCLC,PPARA,PRICKLE1,RUNX3,COL7A1,FXR2,BBS2,LEPR,MAPK8IP1,LEMD2,CNOT2,BANK1,SWAP70,SERPINA1,SPINT2,NMI,E2F1,ARRB1,SOX8,NDFIP1,UBE2C,AHR,HIPK3,ZBTB33,PKIA |
| 4.234e-04 | -7.77 | glycosylation | biological process | GO:0070085 | 351 | 76 | 16441 | 2455 |
GALNT12,NANS,MGAT5B,ART5,EXT2,MUC16,MUC4,FUT1,RPN2,LMAN1,TFG,TIPARP,MGAT5,SIRT1,SEC23A,SLC35C1,SLC17A5,GALNT7,B3GALNT2,MCFD2,ARF4,VCP,MAN2A2,DDOST,AREG,DOLPP1,GNPTAB,B4GALT3,POMT1,ST3GAL1,POMGNT2,CMAS,TRAPPC10,MAN1A2,GNE,PDIA3,CTSZ,B4GALT4,POMGNT1,ADAMTSL4,B4GALNT1,CALR,B3GALNT1,FUT2,CTSC,MGAT1,A4GALT,MGAT4A,ALG13,FUT8,UBE2J1,STT3B,SLC35A1,PPP6R1,TMED2,TRAK2,GCNT1,GFPT1,B3GALT6,NAGPA,B3GNT7,MLEC,B3GNT2,MGAT4B,GYLTL1B,PARP4,C1GALT1C1,COL7A1,FUCA1,GALNT3,SERPINA1,UAP1,GLB1,CTSA,B4GAT1,ALG2 |
| 4.238e-04 | -7.77 | DORN_ADENOVIRUS_INFECTION_12HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_12HR_DN | 33 | 13 | 17758 | 2588 |
TOP2A,CCND1,H1F0,NFKBIA,FHL2,SGK1,TNFRSF12A,COL7A1,EFNA1,SRSF5,CD83,ELF3,IER3 |
| 4.240e-04 | -7.77 | GARY_CD5_TARGETS_UP | MSigDB lists | GARY_CD5_TARGETS_UP | 457 | 93 | 17758 | 2588 |
GAA,AGRN,TP53,PKP2,PJA2,MAP1LC3B,TNFSF9,GNB2,KIAA1147,CALM2,NUP210,DLG1,ETHE1,NFKB2,IL10RB,GM2A,CTH,SUSD3,PCGF5,LOC81691,MBP,CD55,SEPT6,SAT1,NFE2L1,BNIP3L,CCBL2,AURKB,ADRBK2,TYSND1,SGPP1,FYN,MID1IP1,STAT1,SH3GLB2,CAB39,DHTKD1,GLCCI1,ALDH6A1,ENO2,TBC1D1,DHPS,HLA-E,DCAF7,FLOT1,ASL,STRN4,CALM3,PKN1,NUCB2,TIPRL,NFAT5,DUSP5,AIP,ICAM1,CALR,GNS,WDFY1,ADRBK1,PPP1R10,PFKL,CDK16,RIMS3,CD22,FXYD5,FNIP1,SLC44A2,SORL1,FAM102A,CD70,CNOT6L,MYLIP,KDELR1,ZC3H11A,AMFR,MGAT4B,CALM1,PPARA,HMG20B,CAPNS1,RUNX3,NPC2,LEPR,CD83,NCOA3,TRIM69,NFKBIA,UACA,HMGA1,TMEM120A,TMEM159,IRF1,DMPK |
| 4.246e-04 | -7.76 | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | MSigDB lists | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | 63 | 20 | 17758 | 2588 |
GAA,CLCN3,ELK3,NF2,HSPG2,THRA,EMP3,CUL1,PYGL,TXK,NUCB1,TIMP3,PFKL,ATP7B,STAT6,CSF1,CKS1B,IRF2,ERCC2,TUBA4A |
| 4.246e-04 | -7.76 | BASSO_CD40_SIGNALING_DN | MSigDB lists | BASSO_CD40_SIGNALING_DN | 63 | 20 | 17758 | 2588 |
ORAI2,PTPN18,IGFBP6,RAPGEF2,BIK,ARL4C,PRKAR2B,TRIB2,HDAC9,RASGRP2,ALDH5A1,METTL7A,RIMS3,BMP7,BCL6,UBE2J1,TTC9,CTDSP2,SYK,GCNT1 |
| 4.246e-04 | -7.76 | MODULE_291 | MSigDB lists | MODULE_291 | 63 | 20 | 17758 | 2588 |
MYL9,P2RX4,FOXM1,TRIP10,SOD2,GDF15,ATP1B1,ETS1,LGALS3BP,IER3,SEMA4D,MGAT1,SECTM1,DNM2,RAB31,TAX1BP3,NRG1,PIEZO1,PDXK,LGMN |
| 4.257e-04 | -7.76 | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | 188 | 45 | 17758 | 2588 |
LASP1,SERPINE2,ARHGEF7,RASA2,NDC80,ERI2,PDCL,KIF23,RACGAP1,CCNB1,STIL,LBR,KTN1,IER3,ZFP36,RANBP1,SORL1,H2AFY,ATP8B1,AHCY,PTPRE,PPP6R1,MSH6,METAP2,HES1,TAF5,MBP,ALDH2,MMD,SNTB2,SAT1,AURKB,MEST,ASB13,KDM4D,FOXD2,FUCA1,GNAS,NEIL3,NAB2,PKD2,PIK3C2B,STK39,GEM,ACOT7 |
| 4.257e-04 | -7.76 | GSE2197_IMMUNOSUPPRESSIVE_DNA__VS_UNTREATEDIN_DC_DN | MSigDB lists | GSE2197_IMMUNOSUPPRESSIVE_DNA__VS_UNTREATEDIN_DC_DN | 188 | 45 | 17758 | 2588 |
GAS2L1,TRIM24,CAST,NKRF,NANS,TRIB2,SLC9A3R2,CAPN2,WEE1,KCTD15,CCNA2,RINL,OPN3,MTMR10,KIF22,RCAN3,MAPK7,PHKG2,NAGPA,TIMP2,ING1,FZD4,ASPM,FHL2,ACO1,STRADB,ZSCAN12,RAD17,BORA,PDIK1L,RANBP9,ULK2,FOXD2,TRIM9,TRIM47,INSR,DHRS13,HOXA9,WFS1,AURKA,SSNA1,TMEM120A,LSM14B,CBX5,GAB1 |
| 4.257e-04 | -7.76 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDM_DN | 188 | 45 | 17758 | 2588 |
GRN,OTUD5,PARP12,TMEM184B,ARMCX3,IL15RA,TBC1D1,PSME2,RASA2,CUL4B,DGKA,ETNK1,PDCL,CHAC2,TMCC3,ZFP36,FOSB,SMAGP,ENPP4,FIGNL1,FOXJ2,PIK3R1,NUB1,RC3H2,SERTAD3,RNPEP,RANBP9,NMT2,ARHGAP24,PI4K2B,MSL1,RBL1,RND3,P4HA2,UBE2D2,NFKBIZ,CHMP4B,ETAA1,RBM43,RGS14,NRBP1,CBX4,RAD21,TMEM131,ABCG1 |
| 4.257e-04 | -7.76 | GSE7460_TREG_VS_TCONV_ACT_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_UP | 188 | 45 | 17758 | 2588 |
MYL9,LMO7,CCDC109B,RUNX2,FAM129B,ITGA6,SDC4,NDUFA4,GMCL1,TGFBR1,HMGN3,CD274,BCL2L1,SPSB1,DUSP5,ICAM1,MXD1,ZFYVE16,RB1,SIPA1L2,CASC4,PRICKLE3,SLC44A1,SNX16,TNFRSF18,APIP,FAIM,TIAM1,CPD,PLSCR1,FHL2,GGH,ERBB2IP,DUSP4,KLHL2,PIAS3,MPRIP,RAB11FIP2,LRIG1,STAT1,YOD1,EFNA5,NFKBIZ,GEM,LRRC57 |
| 4.284e-04 | -7.76 | positive regulation of MAPK cascade | biological process | GO:0043410 | 596 | 119 | 16441 | 2455 |
SPRED1,AVPI1,TRIM5,PSME2,EPHA4,NRG2,P2RX7,ERBB2,RASGRP3,PSME1,NENF,PDGFB,FLT3,ERP29,SPTB,GRM5,TP73,CALM2,PDGFA,ST5,PSMD1,CTNNB1,CTGF,NPNT,SHC3,PSMC2,DAB2IP,RASGEF1A,F2R,RASGRP1,DVL2,FRS3,MAP3K3,SOD1,TIMP2,RIPK2,FZD4,CD40,CDK1,MAP3K6,FZD7,IRS2,PLCG1,FYN,JAK1,ANKRD6,PSMD3,TBX1,MADD,KIAA1804,NOD2,MAP3K11,PRKCDBP,SPTBN5,NRG1,F2RL1,PSMC1,GAB1,TAOK2,TAB3,RASA2,TRAF2,PRKAA1,PSMD7,CALM3,PSMD10,SORBS3,TGFBR1,PKN1,DUSP5,FGF19,ICAM1,BMP2,PDCD10,ADORA1,IRAK1,IGF1R,PTEN,MAP3K9,MAPK11,MDFIC,MYDGF,ERBB3,NCAM1,MAP3K7,IQGAP3,SYK,SPRY2,CAMK2G,PSMA5,MDFI,RASGRF1,PSMB4,MAPKAPK3,RAPGEF2,CALM1,GRIN1,PDE5A,ILK,PSMA4,EGFR,RASA1,FAS,MAPKAPK2,BANK1,INSR,FGFR2,PELI2,FGF18,RYK,ARRB1,GRIN2D,GPER1,EFNA1,FZD5,MAP3K5,CD81,JAK3,XDH |
| 4.289e-04 | -7.75 | Small cell lung cancer | KEGG pathways | ko05222 | 86 | 26 | 6908 | 1076 |
CCNE2,AKT1,TRAF2,ITGA6,PIK3R1,CASP9,TP53,XIAP,COL4A5,BCL2L1,ITGA2B,CCND1,PTGS2,RB1,ITGA3,PTEN,NFKBIA,E2F1,PIK3CA,PIAS2,CKS1B,CDKN1B,PIK3CD,ITGAV,TRAF5,CKS2 |
| 4.289e-04 | -7.75 | Small cell lung cancer | KEGG pathways | hsa05222 | 86 | 26 | 6908 | 1076 |
CCNE2,AKT1,TRAF2,ITGA6,PIK3R1,CASP9,TP53,XIAP,COL4A5,BCL2L1,ITGA2B,CCND1,PTGS2,RB1,ITGA3,PTEN,NFKBIA,E2F1,PIK3CA,PIAS2,CKS1B,CDKN1B,PIK3CD,ITGAV,TRAF5,CKS2 |
| 4.322e-04 | -7.75 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | 167 | 41 | 17758 | 2588 |
KLF2,TRAPPC10,FAM199X,DNAJC3,ITGA6,EPHA4,HABP4,ERBB2,PDGFRL,SNN,TRIB2,DNAJB9,SCML1,MARCH8,OTUD1,AIM1,SGK1,PIM1,MARCH2,ZRANB1,MYLIP,TIPARP,C9orf72,DUSP1,KIFC2,SOCS3,TXK,IRS2,NAAA,PELI2,WDR19,BMP1,CSGALNACT1,NR4A2,NFKBIZ,KLF11,EPB41L4A,ZNF502,MAFF,TOB1,PCSK5 |
| 4.384e-04 | -7.73 | cellular response to oxygen levels | biological process | GO:0071453 | 133 | 35 | 16441 | 2455 |
PINK1,NKX3-1,SLC2A4,CPEB4,EPAS1,NDRG1,PRKAA1,TP53,CCNB1,ICAM1,PICK1,LMNA,IRAK1,P4HB,PTEN,BMP7,VASN,TWIST1,CITED2,EGLN3,HP1BP3,SIRT1,AKT1,TCEB2,RGCC,SLC11A2,PDK3,FAS,PTGS2,UBE2D2,E2F1,CPEB2,ARNT,EGLN1,DRD1 |
| 4.393e-04 | -7.73 | REACTOME_MITOTIC_G2_G2_M_PHASES | MSigDB lists | REACTOME_MITOTIC_G2_G2_M_PHASES | 77 | 23 | 17758 | 2588 |
PLK1,CEP70,TUBB4B,PRKAR2B,PKMYT1,CCNB1,PRKACA,CDC25C,CDK1,CKAP5,WEE1,CCNA2,CNTRL,CENPJ,TUBGCP6,PLK4,E2F1,NEK2,TUBG1,SSNA1,CEP41,CCNB2,TUBA4A |
| 4.424e-04 | -7.72 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP | 183 | 44 | 17758 | 2588 |
DYNLRB1,BMF,FAM92A1,CHCHD7,CKAP2,CNOT8,SDC4,ERCC6L,C5orf30,CBLL1,LYNX1,CKAP5,KIF5B,MDM1,KCNK5,CST3,FCHO1,PRKCI,TUBG1,CLDN4,RTKN2,MXD3,MED30,CTDSP2,SMC4,WBP5,METAP2,PSRC1,KIAA1841,CEP89,PCBP3,UBE2A,CDCA2,GTF2A2,TP53INP2,SKA1,CDKN2AIPNL,TTC12,NETO2,ACADM,LSM14B,ZC3HC1,ZBTB33,PHC1 |
| 4.424e-04 | -7.72 | V$HFH3_01 | MSigDB lists | V$HFH3_01 | 183 | 44 | 17758 | 2588 |
RUNX2,REPS2,CPEB4,CHCHD7,GRIK2,ETV5,TSPAN17,SCML1,FOXP2,KCTD15,ITGA3,ARTN,CYR61,WDR44,VASN,FUT8,SLC44A1,SGK1,TWIST1,NCAM1,DUSP1,CYP26B1,SSH3,SMARCA2,SLC39A8,RGAG1,RAB3IP,PRX,NIN,KLF12,COL13A1,NKD1,NR4A3,PPP1CB,ADAMTS14,C1orf43,REEP4,SHOX2,CDAN1,NR3C2,TOB1,KLF7,RGMA,RAD21 |
| 4.424e-04 | -7.72 | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP | 183 | 44 | 17758 | 2588 |
CCNC,UNC93B1,HJURP,MRPS15,DNAJC3,BIK,FLOT1,C5orf30,SLC36A4,INTS8,COMMD5,CACNB4,ECI1,AIP,FAM111A,ZYX,PCNA,FDXR,CST3,BAX,TMEM143,TUBG1,BRI3,APIP,LMAN1,SGCB,SPRY2,PSMB4,PAPD7,DBR1,CASP4,MPV17L2,ULK2,GINS4,DHDH,IRS2,TRIM45,PRDM5,DCUN1D1,MAPK13,WDR91,AKIP1,WDR62,NDE1 |
| 4.460e-04 | -7.72 | regulation of leukocyte apoptotic process | biological process | GO:2000106 | 80 | 24 | 16441 | 2455 |
SIRT1,ADAM17,LGALS3,TSC22D3,RAPGEF2,TP53,P2RX7,PRKCQ,AURKB,CD274,MERTK,BCL10,IRS2,PTEN,AXL,BCL6,NOD2,BAX,NR4A3,FNIP1,IRF7,SLC39A10,RAG1,JAK3 |
| 4.464e-04 | -7.71 | adrenal_gland-extraadrenal-pheochromocytoma | COSMIC cancer mutations | adrenal_gland-extraadrenal-pheochromocytoma | 4 | 4 | 17775 | 2585 |
GNAS,CDKN2C,PTEN,RET |
| 4.488e-04 | -7.71 | C2 | smart domains | SM00239 | 135 | 37 | 9131 | 1455 |
PLA2G4A,DOC2A,RASA2,MCTP2,BAIAP3,SYTL4,PKN1,SYTL2,SYDE2,WWP2,CPNE2,RGS3,RIMS3,PLCG2,PIK3CA,DAB2IP,CADPS2,WWP1,PLCB2,SYTL3,RIMS2,MCTP1,CAPN6,ITCH,ESYT1,ABR,RASA1,PLCH1,PLCG1,SYT7,RAB11FIP2,RAB11FIP1,DYSF,PIK3C2B,SYT13,TC2N,ESYT2 |
| 4.492e-04 | -7.71 | MSN (moesin) | protein interactions | 4478 | 121 | 34 | 16036 | 2547 |
ENO2,PPP1R2,SELL,ISYNA1,NOTCH2,BCAP31,ICAM1,PDIA4,PLS3,CD46,CALR,RCN1,CAPN2,CTNNB1,P4HB,PAPSS1,AKR1B1,AHCY,TAGLN2,SYK,TSPAN33,VPS11,RHOA,EZR,PRKCQ,IGSF8,PLS1,LCP1,FAS,HLA-B,TSC1,HSPB1,CD81,L1CAM |
| 4.495e-04 | -7.71 | - | gene3d domains | 2.60.40.150 | 146 | 39 | 9988 | 1574 |
PLA2G4A,DOC2A,RASA2,MCTP2,BAIAP3,SYTL4,PKN1,SYTL2,SYDE2,WWP2,CPNE2,RGS3,RIMS3,PLCG2,PIK3CA,DAB2IP,WWP1,PIK3CD,PLCB2,SYTL3,RIMS2,MCTP1,CAPN6,ITCH,PRKCQ,ESYT1,ABR,RASA1,PLCG1,PLCH1,SYT7,RAB11FIP2,INPP4B,RAB11FIP1,DYSF,PIK3C2B,SYT13,TC2N,ESYT2 |
| 4.495e-04 | -7.71 | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | MSigDB lists | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | 121 | 32 | 17758 | 2588 |
GRN,PRSS8,TMEM184B,HLA-E,CTSB,DNAJB2,SDC4,TAP1,SOD2,MAP1LC3B,DUSP5,RND1,TIMP1,RRBP1,CD9,TRIM21,TACSTD2,IFIT1,LGMN,MYRIP,DUSP1,CD55,MFI2,PLAUR,SAT1,ATP1B1,ARF4,MMP15,PTGS2,AREG,P4HA2,STAT1 |
| 4.495e-04 | -7.71 | SENESE_HDAC1_TARGETS_UP | MSigDB lists | SENESE_HDAC1_TARGETS_UP | 423 | 87 | 17758 | 2588 |
CCNE2,SPRED1,IQGAP1,SOD2,BCL2L1,PHLDA1,CYP1A1,ENTPD4,SRPX,IL6ST,KLF3,ATP13A3,DLG1,PLK4,STEAP3,CTTN,TMEM64,NFKB2,LMAN1,GM2A,PPIF,DOCK4,PCGF5,TRIM8,CD55,HN1L,LGALS8,SLC39A8,FOPNL,CYB5R2,EZR,DNAJB14,LDB2,TRUB1,LCP1,SGPP1,UEVLD,CANT1,MAOA,NFKBIZ,MLKL,MAFF,NXT2,CPEB4,ITGA6,TGFBR1,RAB6A,POMGNT1,ETS1,DUSP5,DNAJB9,HDAC9,RASSF8,BMP2,RAC2,RB1,CA2,SLAIN2,BUB1,TNFRSF12A,MAST4,TMED2,TMX1,ELK3,RGMB,TCFL5,EIF5A2,KBTBD8,SPAG1,STX3,DCP2,FAS,SLCO4A1,DDAH1,SLC6A6,KBTBD2,NFKBIA,ITPR1,OTUB2,FGD6,OSMR,YOD1,HMGA1,GEM,TOB1,ESYT2,USP16 |
| 4.497e-04 | -7.71 | V$SP1_Q6 | MSigDB lists | V$SP1_Q6 | 237 | 54 | 17758 | 2588 |
KLF2,UGP2,HOXB7,GGA1,IQGAP1,THRA,NDRG1,RHBDL3,NRG2,TIPRL,NFAT5,SH3KBP1,ZFYVE16,APLP2,FLII,SNX18,FAM160A2,CDKL5,PRICKLE3,SLC46A1,CNNM4,KANK2,ERBB3,CACNA1D,MAP3K7,MYLIP,CAMK2G,CPD,CYP26B1,DRAP1,LYRM1,NUB1,CLSTN1,PRKRA,ELK1,PDIK1L,GNA11,CDK5R1,RAB2B,IRX3,PIAS3,ONECUT1,FNTA,TIMP3,PTK7,SLC9A6,CORO1C,SH2D3C,MAP3K11,AGBL5,NXPH4,PITPNA,KLF11,STARD13 |
| 4.500e-04 | -7.71 | adrenal_gland-pheochromocytoma | COSMIC cancer mutations | adrenal_gland-pheochromocytoma | 50 | 17 | 17775 | 2585 |
NF2,AKT1,RET,TP53,ERBB2,IDH1,FLT3,EGFR,GNAS,RB1,CTNNB1,CDH1,PTEN,FGFR2,SMO,PIK3CA,JAK3 |
| 4.510e-04 | -7.70 | KINESIN_MOTOR_2 | prosite domains | PS50067 | 44 | 16 | 11866 | 1802 |
KIF3C,KIF20A,KIFC2,KIF1C,KIF23,KIF20B,KIF13A,KIF2C,KIF11,KIF26A,KIF5B,KIF13B,KIF14,KIF22,CENPE,KIF12 |
| 4.519e-04 | -7.70 | STK33_NOMO_DN | MSigDB lists | STK33_NOMO_DN | 259 | 58 | 17758 | 2588 |
EXPH5,MFSD3,ANXA3,MZT1,LGR4,SLC16A14,PLEKHJ1,ST14,GALNT12,BIK,RET,ASL,SELL,PDGFRL,ZNRF3,PM20D2,CAMK1D,FLT3,IL18R1,BEX2,NEO1,SYDE2,C16orf74,DOPEY2,SPIN4,MGAT4A,FDXR,AIM1,PCYOX1,TMEM143,ZDHHC23,VAT1,ACOX2,EGLN3,RASGRP1,LAMP3,PCCB,CDA,CR2,PLS1,HEATR5A,CYFIP2,TMTC2,TCEAL8,ALCAM,FANCE,CYP4F3,PLCH1,DDAH1,H1F0,MATN2,KIAA1804,KLF5,PLXND1,CHPT1,CXorf56,FAM134B,NXT2 |
| 4.533e-04 | -7.70 | phosphatase binding | molecular function | GO:0019902 | 154 | 39 | 16491 | 2452 |
TPRN,SPRED1,HSP90B1,TRAF2,IQGAP1,TP53,STRN4,ERBB2,SLC9A3R2,SH2D4A,SYTL2,SH3RF2,CTNNB1,CTSC,KCNN4,PPME1,DLG1,NEK2,CDKN1B,DAB2IP,CRY2,DLG3,PPP6R1,SOD1,AKT1,PIK3R1,PPARA,VCP,EGFR,HSF4,IRS2,CARHSP1,JAK1,STAT6,PPP2R4,CABIN1,MAP3K5,JAK3,DRD1 |
| 4.543e-04 | -7.70 | MHC_I_a_C | interpro domains | IPR010579 | 4 | 4 | 18293 | 2672 |
HLA-B,HLA-C,HLA-E,HLA-A |
| 4.552e-04 | -7.69 | PLXNB1 (plexin B1) | protein interactions | 5364 | 17 | 9 | 16036 | 2547 |
PLCG1,RHOA,AKT1,RND3,ARHGEF11,SEMA4D,PLCG2,PLXNA1,RND1 |
| 4.581e-04 | -7.69 | Degradation of the extracellular matrix | REACTOME pathways | R-HSA-1474228 | 89 | 26 | 8202 | 1235 |
CASP3,COL9A3,ADAM17,TIMP2,HSPG2,CTSB,FURIN,COL18A1,CAPNS1,COL12A1,MMP15,CTSL,SPP1,TIMP1,CDH1,COL13A1,MMP17,CTSV,BMP1,ADAM15,KLK7,CTSD,COL16A1,CAPN1,TLL2,ADAMTS16 |
| 4.591e-04 | -7.69 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | 178 | 43 | 17758 | 2588 |
DDX58,SERPINE2,CDKN1C,IL15,MACC1,GALNT12,GMPR,HERC5,SAMD9,DHRS3,FLT3,LGALS3BP,EPCAM,SLC27A6,CDH1,IL31RA,IFIT1,OAS3,SCN2A,RAB27B,EGLN3,MX1,USP18,PRKAR2B,DUSP4,IFIT3,IRX3,TRIM9,MFAP3L,PTGS2,TIMP3,HOXA9,FGF18,STAT1,INPP4B,NR4A2,IRF7,HS3ST3B1,GEM,CMPK2,IFIH1,IFI6,FAM134B |
| 4.611e-04 | -7.68 | TMEM255A (transmembrane protein 255A) | protein interactions | 55026 | 11 | 7 | 16036 | 2547 |
WWP1,GCA,ANKRD13D,KCTD2,UBASH3B,ITCH,WWP2 |
| 4.615e-04 | -7.68 | BURTON_ADIPOGENESIS_PEAK_AT_2HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_2HR | 50 | 17 | 17758 | 2588 |
NR4A1,FOS,PHLDA1,SLC20A1,RHOB,IER3,PTGS2,WEE1,ETS2,CTGF,CYR61,ZFP36,FOSB,NR4A2,PIM1,CAPN1,DUSP1 |
| 4.620e-04 | -7.68 | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN | 194 | 46 | 17758 | 2588 |
CMAS,ENO2,SPC25,ST14,PSME2,PTTG1,CDCA8,NDUFA4,RACGAP1,TXNDC9,BARD1,PSIP1,SAC3D1,TNS3,DPYSL2,ATP5H,PSMC2,BCL6,H2AFY,APIP,PDIA6,RASGRP1,MSH6,SMC4,SEPHS1,METAP2,HMMR,MRPS33,ALDH2,CLSTN1,RAD17,GTF2A2,ILK,CCNF,ICMT,KIF11,H2AFV,PSMA4,FUCA1,PKD2,MDH1,PLXND1,NUP37,UBE2C,CD81,PSMC1 |
| 4.620e-04 | -7.68 | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDM_UP | 194 | 46 | 17758 | 2588 |
GRN,CHCHD7,MRPS15,HEBP1,TESK2,FAM198B,NANS,COMMD5,SEPP1,EXT2,BCAP31,XPR1,FAM111A,CCNA2,SCNN1A,BDH1,N4BP3,ABCA2,IRF2,PLEKHF1,TNFRSF18,ACOX2,TECR,MSH6,MED22,MBP,PTPN18,MMD,GUSB,LPGAT1,OXR1,KCTD20,EMP3,ATP8B3,RAB38,ANLN,CDK1,TCN2,OSBPL2,CARHSP1,LDLRAP1,SLC25A4,PLA2G15,APPL2,MDH1,CPPED1 |
| 4.633e-04 | -7.68 | condensed nuclear chromosome outer kinetochore | cellular component | GO:0000942 | 4 | 4 | 17570 | 2579 |
PLK1,BUB1,CCNB1,NDC80 |
| 4.633e-04 | -7.68 | PRKCA (protein kinase C, alpha) | protein interactions | 5578 | 249 | 60 | 16036 | 2547 |
DDX58,IBTK,RALBP1,SDC4,HABP4,TP53,GABRG2,SELL,PLD2,F11R,HDAC6,HLA-A,LMNA,PICK1,GRM5,CORO1B,TOP2A,SPP1,APLP2,ADD3,ADRBK1,CTNNB1,NOXA1,PLCG2,PRKG1,CD9,MAPK7,TIAM1,SYK,DVL2,EEF1D,ATP2B1,GFPT1,HES1,MBP,RHOA,PSMB4,PFKFB2,PPARA,GRIN1,VPS4B,TEP1,EZR,SCRIB,CBL,EGFR,SPAG1,FAS,INSR,ATP1A1,MYLK,NFKBIA,KLF5,HMGA1,PLD1,ITPKA,NRGN,TRPC3,AFAP1,OCLN |
| 4.637e-04 | -7.68 | REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | MSigDB lists | REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | 464 | 94 | 17758 | 2588 |
PLA2G4A,CCNC,MTM1,ACACB,HSPG2,CPT2,PNPLA2,HEXB,ETNK1,PHOSPHO1,PLA2G16,LPIN3,CDIPT,SDC1,PRKACA,ECI1,CYP39A1,CDS1,INPP5E,CYP1A1,CTGF,GRHL1,P4HB,SLC44A1,FABP6,PIK3CA,AKR1B1,PIK3CD,ACOX2,ACSL4,PPP1CA,TECR,LGMN,FAR1,MED30,GM2A,CERS2,AGPS,IDH1,SGPP1,SLC44A3,KDSR,PI4K2B,AGPAT2,CDK19,WWTR1,INPP4B,BMP1,PPP1CB,SLC27A1,PIK3C2B,GLA,CHPT1,ABCA1,PRKAA2,INPPL1,CDS2,ELOVL7,ASAH1,PLD2,LBR,TEAD3,SGPL1,OXCT1,PTEN,ARSG,OCRL,BDH1,SLC44A2,ABCD1,HMGCL,FAR2,PIKFYVE,NCOA2,MED22,FADS2,PCCB,LPGAT1,PIK3R1,ELOVL3,PPARA,FHL2,SPTLC2,ARSK,NCOA3,PRKAG2,LDLRAP1,DGAT2,CTSA,GLB1,ACADM,PLD1,ARSB,ABCG1 |
| 4.638e-04 | -7.68 | INTRACELLULAR_SIGNALING_CASCADE | MSigDB lists | INTRACELLULAR_SIGNALING_CASCADE | 659 | 127 | 17758 | 2588 |
CASP3,SPRED1,NF2,RALBP1,DGKA,TP53,MRAS,BCL2L1,SLC20A1,CARD10,PICK1,GRM5,HTR1D,ARHGEF10L,TP73,DAPK2,CCNA2,RPS6KA2,TSPAN6,RGS3,IL31RA,DUSP10,TAX1BP3,TFG,F2R,MED30,RASGRP1,MAP3K3,SOD1,CXXC5,MARK1,RIPK2,AKT1,CASP9,PTGER4,ARHGDIB,PRKAR2B,RAD17,DUSP4,CD40,MAP3K6,STK17B,VCP,ABR,EDNRA,SOCS3,PLCH1,CARHSP1,FYN,DNM1L,PLK2,LIMK1,SH2D3C,STK38,SECTM1,MADD,KIAA1804,STAT1,MAP3K11,NOD2,CANT1,ADIPOR1,MAPK13,ARF6,ARHGAP4,TRAF5,AIFM3,ABCA1,PRKAR1A,FGD1,TAOK2,PINK1,ARAP3,TRAF2,BIK,CCM2,PLD2,NOTCH2,PKN1,DIRAS3,TOP2A,CARD8,IRAK1,PTEN,BAX,MAP3K9,DAPK1,ZDHHC13,SLC44A2,MDFIC,MAPK11,MAP3K7,PIKFYVE,PLCB2,EEF1D,FARP2,MDFI,RHOA,AMFR,CORO2A,STAT4,LITAF,CALCRL,EGFR,MAPK8IP1,RHOB,PRDX4,STK17A,BCL10,GNAS,MAPKAPK2,TSC1,DDAH1,CASP7,SCG2,NMI,NR4A3,ARAP1,FGD6,PLD1,MAP3K5,NDFIP1,CD81,IFI6,ZBTB33,DMPK,DRD1 |
| 4.657e-04 | -7.67 | Hemostasis | REACTOME pathways | R-HSA-109582 | 515 | 105 | 8202 | 1235 |
PLA2G4A,KIF3C,INPP5D,KLC2,DGKA,TP53,GATA3,F11R,KIF2C,ITPR2,PDGFB,PRKACA,KIF26A,GNB2,CALM2,PDGFA,WEE1,STIM1,PLCG2,PIK3CA,IRF2,KIF22,PIK3CD,F2R,RASGRP1,TUBA4A,LAMP2,DOCK4,SOD1,AKT1,PRKCQ,PRKAR2B,F12,ATP1B1,ITPR3,DOCK5,PLCG1,FYN,KCNMB4,JAK1,PPP2R5A,ABHD12,HDAC1,SERPINB6,IRF7,PPP2R5D,MAFF,PRKAR1A,SERPINE2,CD63,ITGA6,DGKQ,HABP4,KIF23,SELL,CALM3,RACGAP1,DOCK11,MERTK,SIRPA,ITGA2B,KIF5B,RAC2,ITGA3,TIMP1,GNB5,GATA2,KLC3,PRKG1,CD9,AK3,DGKG,SYK,ATP2B1,RHOA,KIF20A,PLAUR,PIK3R1,CALM1,HMG20B,PDE5A,YES1,BCAR1,KIF11,GNA11,DGKE,RHOB,RASGRP2,PDE11A,GNAS,DGKH,SERPINA1,PRCP,ITPR1,ARRB1,ATP1B3,CENPE,ITGAV,CBX5,JAK3,TRPC3,L1CAM,IRF1,DOCK9,EHD1 |
| 4.662e-04 | -7.67 | KYNG_DNA_DAMAGE_UP | MSigDB lists | KYNG_DNA_DAMAGE_UP | 221 | 51 | 17758 | 2588 |
LRRFIP2,SOX9,CTDSPL,ERBB2,SLC1A3,RAB6A,CRABP2,PHLDA1,FBLN1,IL18R1,DUSP5,CYP39A1,NRP2,APPBP2,MECOM,SGPL1,ATP6V0B,VASP,HSF2,PDCD10,KIF14,PPME1,ENPP5,MITF,MTMR10,USP1,AHCY,ARNT2,DLX4,SYK,GM2A,ABCC1,CKS2,MYO5B,SEC23A,PCDH1,GCLC,EPHA1,PTGFRN,EGFR,CYB5A,IL1R1,CD8A,KCNK1,SLC9A6,CTNND1,GDF11,ARNT,CYBRD1,RPS6KA3,PCSK5 |
| 4.672e-04 | -7.67 | Protein processing in endoplasmic reticulum | KEGG pathways | ko04141 | 168 | 43 | 6908 | 1076 |
HSP90B1,SEC61G,MAN1A2,DNAJC3,DNAJB2,TRAF2,FBXO2,PDIA3,CUL1,DNAJB11,FBXO6,ERP29,BCAP31,RAD23A,PDIA4,CAPN2,CALR,P4HB,RRBP1,BAX,UBE2J1,RPN2,STT3B,LMAN1,PDIA6,TRAM1,HSPA2,CKAP4,SEC23A,UFD1L,SEC61B,ERLEC1,AMFR,ERO1A,EIF2AK1,VCP,DNAJC10,DDOST,WFS1,UBE2D2,YOD1,MAP3K5,CAPN1 |
| 4.672e-04 | -7.67 | Protein processing in endoplasmic reticulum | KEGG pathways | hsa04141 | 168 | 43 | 6908 | 1076 |
HSP90B1,SEC61G,MAN1A2,DNAJC3,DNAJB2,TRAF2,FBXO2,PDIA3,CUL1,DNAJB11,FBXO6,ERP29,BCAP31,RAD23A,PDIA4,CAPN2,CALR,P4HB,RRBP1,BAX,UBE2J1,RPN2,STT3B,LMAN1,PDIA6,TRAM1,HSPA2,CKAP4,SEC23A,UFD1L,SEC61B,ERLEC1,AMFR,ERO1A,EIF2AK1,VCP,DNAJC10,DDOST,WFS1,UBE2D2,YOD1,MAP3K5,CAPN1 |
| 4.701e-04 | -7.66 | negative regulation of cell-substrate adhesion | biological process | GO:0010812 | 49 | 17 | 16441 | 2455 |
CASK,NF2,MFI2,FZD4,DMTN,PIK3R1,FBLN1,FZD7,RASA1,AP1AR,PTEN,ACVRL1,CORO1C,TBCD,BCL6,ADAM15,TACSTD2 |
| 4.737e-04 | -7.65 | negative regulation of cell cycle G1/S phase transition | biological process | GO:1902807 | 104 | 29 | 16441 | 2455 |
PSMB4,PSME2,CTDSPL,PSMD7,TP53,PSMD10,PSME1,PSMA4,TP73,SUSD2,CCND1,JADE1,E2F7,RB1,PSMD1,PTEN,DACT1,PSMD3,PSMC2,FBXO7,BRD7,CDKN1B,KANK2,PKD2,FHL1,PSMC1,CTDSP2,PSMA5,CTDSP1 |
| 4.737e-04 | -7.65 | positive regulation of cell migration | biological process | GO:0030335 | 369 | 79 | 16441 | 2455 |
ACVR1,ATP8A1,RET,COL18A1,GATA3,CD274,CAMK1D,HDAC6,PDGFB,PDGFA,DAPK2,TNFRSF18,DAB2IP,SEMA3G,EPB41L4B,PDE4D,PIK3CD,F2R,SEMA3B,DOCK4,BAG4,AKT1,DMTN,SYNE2,DOCK5,IRS2,PTGS2,PLCG1,MYLK,FAM110C,F2RL1,HSPB1,SEMA6B,ANXA3,LGALS3,ARHGEF7,SOX9,SELL,CBLL1,ETS1,FBLN1,SRPX2,ICAM1,NRP2,ITGA2B,HDAC9,CALR,BMP2,RAC2,CXCL16,PDCD10,ITGA3,IGF1R,CYR61,EPB41L5,SUN2,RHOA,ADAM17,RAPGEF2,ANO6,PIK3R1,FURIN,KIF20B,EPHA1,ILK,BCAR1,EGFR,GPLD1,ONECUT1,SWAP70,INSR,SEMA4D,PLPP3,CSF1,FGF18,ITGAV,GPER1,SEMA3A,DRD1 |
| 4.759e-04 | -7.65 | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP | 173 | 42 | 17758 | 2588 |
TXN,DYRK3,TRIP10,SDC4,SOD2,IL18,CD274,EGR3,DUSP5,ICAM1,RND1,IER3,OTUD1,E2F7,BTG3,SELK,RPGR,MSH6,DUSP1,HES1,B3GNT2,RIPK2,NR4A1,PLAUR,RAPGEF2,PTGER4,PIM3,SAV1,CDK1,SOCS3,CD83,PTGS2,ETS2,AREG,MFSD2A,NFKBIA,NR4A3,NR4A2,NFKBIZ,PLD1,MAFF,NXT2 |
| 4.759e-04 | -7.65 | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP | 173 | 42 | 17758 | 2588 |
BIN1,MAN2B2,SIGIRR,GALNT12,NDRG1,TSC22D3,UBASH3B,EPHA4,HABP4,SNN,H1FX,CORO1B,TMCC3,FAM111A,NUP210,LLGL2,DUSP10,ETHE1,FLOT2,KCTD3,TMEM9,S100A6,DUSP1,SUSD3,FBXL16,CASP9,DIAPH2,STMN3,NPC2,LDB2,RNPEP,TP53INP2,SFXN5,GABARAPL1,IRS2,TRAM2,DHRS13,AREG,PELI2,PIEZO1,TOB1,KLF7 |
| 4.759e-04 | -7.65 | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | 173 | 42 | 17758 | 2588 |
TXN,DYRK3,TMEM217,GNPDA1,UBASH3B,ADO,SNX9,DUSP5,SCML1,M6PR,ZFYVE16,SPP1,SGK1,RAB20,EGLN3,CKS2,WBP5,DUSP1,P2RX4,MFI2,LONRF3,KBTBD8,MGAM,SLC17A5,DUSP4,FNDC3A,RHEB,BCAR3,IL1R1,SLCO4A1,PTGS2,PRKAG2,ETS2,UAP1,CORO1C,CSF1,NAB2,GLA,GEM,ZC3HC1,ESYT2,RRAGD |
| 4.773e-04 | -7.65 | kidney morphogenesis | biological process | GO:0060993 | 85 | 25 | 16441 | 2455 |
HES1,LGR4,FMN1,SOX9,DCHS1,GATA3,ILK,NPHP3,IRX3,BMP2,CTNNBIP1,FAT4,CTNNB1,NPNT,GPC3,FRAS1,WWTR1,SMO,DLG1,PKD2,TACSTD2,SOX8,OSR1,ADAMTS16,GCNT1 |
| 4.774e-04 | -7.65 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | 205 | 48 | 17758 | 2588 |
IER5L,FARP1,KLK10,SLC2A8,RET,MORC4,SYTL4,DHRS3,FAM46C,NCS1,CCND1,C16orf74,SCNN1A,MLPH,CYP4F11,A4GALT,LHX6,REEP1,TMEM51,FAM102A,SULT2B1,TIPARP,TIAM1,OSGIN1,CYP1B1,SEMA3B,SUSD3,CXXC5,CELSR2,PRSS23,SYBU,MYEOV,FHL2,ASB13,CDK5R1,SEC14L2,TRIM47,SMTNL2,PDLIM3,TJP3,DHRS2,MFSD2A,WFS1,LRIG1,XRCC3,SOX8,PTGES,RAB3IL1 |
| 4.813e-04 | -7.64 | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | 189 | 45 | 17758 | 2588 |
SLC35D2,ARHGEF3,SORBS1,RUNX2,JKAMP,UBASH3B,TMX4,MCOLN3,RGS20,GRK6,RAB6A,MAP1LC3B,TTYH3,SNX13,OTUD1,UBE2Q2,CYP2S1,CEP78,ZDHHC23,SORL1,C10orf54,C12orf75,TPCN1,TMBIM1,SMC4,P2RX4,CXXC5,PANK1,UTRN,ARFRP1,SRSF5,B3GALNT2,SESN1,FAM177A1,LDLRAP1,FASTKD1,UAP1,MADD,UBE2D2,APPL2,DTX4,ACADM,PIEZO1,GLCCI1,CBX7 |
| 4.813e-04 | -7.64 | EGFR_UP.V1_DN | MSigDB lists | EGFR_UP.V1_DN | 189 | 45 | 17758 | 2588 |
LTBP1,COL9A3,TRIM24,DEPDC1,TSC22D3,HEBP1,CALB2,EPS8,OSR2,EGR3,HERC6,PRR7,STIL,RCN1,BTG3,ADD3,IGF1R,LLGL2,ALG13,BDH1,ELF5,PCYOX1,SGK3,SGCB,CPE,RASGRP1,SNX7,CYP26B1,ENPP4,CDKN2AIP,DCAF6,CELSR2,MICB,SLC39A8,KIF11,C18orf8,MDK,PDLIM3,MATN2,SH3GLB2,ANXA9,NCAPG2,SLC27A3,IFI6,E2F8 |
| 4.813e-04 | -7.64 | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN | MSigDB lists | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN | 189 | 45 | 17758 | 2588 |
OTUD5,KLF2,UNC93B1,SORT1,MCOLN3,WDTC1,STRN4,FTH1,CTSZ,TRIB2,SDC1,SIRPA,APOBEC3B,ANK1,TGFBR3,FRY,METTL7A,ZFP36,BDH1,PLCG2,CST3,SGK3,SELK,PACSIN1,C9orf72,TPCN1,FGFR1OP2,SMC4,ADCK3,BCL9,MRPS36,STK17B,ATP10D,XKRX,TMEM50B,NCOA3,INSR,JAK1,STK38,DCUN1D1,SLC25A30,CCDC97,RAB3IL1,TMEM131,FAM134B |
| 4.813e-04 | -7.64 | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP | MSigDB lists | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP | 189 | 45 | 17758 | 2588 |
CCNE2,RMND5A,GOLIM4,SERPINE2,GNPDA1,HLA-E,JKAMP,ARL4C,KIF23,BCL2L1,ITPR2,SEPT4,OAT,MNS1,TIPRL,BTG3,ATP13A3,ECI2,RNASEH2A,LMAN1,RAG1,CDKN2D,MDFI,SEC23A,CLCN3,SMARCA2,TMEM43,ASXL1,ASPM,MPP1,TEF,SPATA13,ANKRD10,CDKN2AIPNL,ETS2,PRDX3,DCK,CSTF2,SLC27A1,PLXND1,ACADM,ISOC1,LRRC57,RRAGD,ABCG1 |
| 4.813e-04 | -7.64 | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | 189 | 45 | 17758 | 2588 |
CD99,TMEM184B,PPP1R2,DAP,MTL5,FBXO2,BAIAP3,ERP29,RSAD1,H1FX,CDK14,DAPK2,APOBEC3B,ITGA3,IMPAD1,FAM63A,KANK2,HSPA13,ACAD8,FAIM,TRAM1,SLC35A1,S100A6,FAM69A,C9orf9,CERS2,NAGPA,GUSB,COG2,USP18,HTATIP2,EIF2AK1,RHOB,ZMPSTE24,MSL1,UAP1,NAT1,TLE1,ARFGAP3,CTSA,PIEZO1,NDFIP1,SLC27A3,HSPB1,ISOC1 |
| 4.840e-04 | -7.63 | single organism cell adhesion | biological process | GO:0098602 | 471 | 97 | 16441 | 2455 |
MYL9,IL15,LFNG,CERCAM,RET,TP53,PKP2,P2RX7,GATA3,MICALL2,FLT3,NOV,CDH1,CTNNB1,NPNT,KIF14,DLG1,CDH3,PIK3CD,CYP1B1,CAMSAP3,RIPK2,TNIP1,PTPRU,FZD4,PTGER4,EZR,MYL12A,LCP1,FZD7,FYN,DDOST,AXL,STAT6,CTNND1,ANXA9,RPL22,HSPB1,F2RL1,FBLIM1,RUNX2,BVES,HLA-E,SOX9,BTN3A1,CBLL1,JAG2,MERTK,IL18R1,SRPX2,ICAM1,ITGA2B,RAC2,CYR61,BMP7,ICAM5,KIF13B,CTPS1,BAX,ARVCF,NTN1,WNT3A,RAG1,SYK,GCNT1,ADAM17,PODXL2,RHOA,MICB,RC3H2,VAMP3,PLEKHA7,SCRIB,VEZT,EPHA1,CYFIP2,FNDC3A,ILK,ANTXR1,EGFR,CDK5R1,FAS,TXK,GNAS,CD8A,TSC1,COL13A1,SEMA4D,PLPP3,ITGA7,ITGAV,EFNA1,ICOSLG,FZD5,AKIP1,L1CAM,IRF1 |
| 4.845e-04 | -7.63 | mesenchyme development | biological process | GO:0060485 | 190 | 46 | 16441 | 2455 |
SEMA6B,ACVR1,RET,SOX9,TGFBR1,NCKAP1,FAM101B,FGF19,EFNB1,SIX4,GBX2,BMP2,TGFBR3,CTNNB1,BMP7,SMO,ADAM15,ACTA2,TWIST1,ERBB3,SEMA3G,WNT3A,CITED2,SEMA3B,EPB41L5,HES1,S100A4,AMER1,LOXL2,EDNRA,PITX2,SEMA4D,HTT,FGFR2,PTK7,CORO1C,TBX1,WWTR1,STAT1,FAM83D,PKD2,NRG1,EFNA1,SOX8,OSR1,SEMA3A |
| 4.869e-04 | -7.63 | TPR-like_helical_dom | interpro domains | IPR011990 | 194 | 46 | 18293 | 2672 |
TTC8,TCF25,ST13,TTC39B,TMTC3,P3H2,DNAJC3,KLC2,ERCC6L,WDTC1,TRAPPC8,GPSM2,AIP,APPBP2,TTC21B,NAPG,NOXA1,TRANK1,FICD,KLC3,IFIT1,VPS11,TMTC1,LONRF3,CFAP46,TTC7A,EMC2,TMTC2,NPHP3,TANC1,IFIT3,CCNF,UNC45B,SPAG1,RGPD5,PEX5,KIAA0141,TTC12,P4HA2,PSMD3,WDR19,P4HA3,CABIN1,TTC9,TANC2,TTC39C |
| 4.872e-04 | -7.63 | PTGFRN (prostaglandin F2 receptor inhibitor) | protein interactions | 5738 | 14 | 8 | 16036 | 2547 |
LGALS3,LGALS8,CD63,A4GALT,CD82,CD9,FBXO6,CD81 |
| 4.872e-04 | -7.63 | SDF2L1 (stromal cell-derived factor 2-like 1) | protein interactions | 23753 | 14 | 8 | 16036 | 2547 |
SLC2A4,SUZ12,PDIA5,DNAJB11,VWA1,FBXO6,SRSF5,EGFR |
| 4.877e-04 | -7.63 | cellular response to peptide hormone stimulus | biological process | GO:0071375 | 454 | 94 | 16441 | 2455 |
SPRED1,SORBS1,SLC2A4,SLC2A8,PSME2,WDTC1,NRG2,ERBB2,RASGRP3,PSME1,PRKACA,PDGFB,SPTB,GNB2,CALM2,PDGFA,ATP6V0B,PSMD1,SHC3,PSMC2,PIK3CA,DAB2IP,GOT1,RASGEF1A,RASGRP1,FRS3,AKT1,PRKAR2B,POR,RHEB,SOCS3,IRS2,ENPP1,FYN,IDE,JAK1,PSMD3,STAT1,CAB39,EIF4EBP2,SPTBN5,NRG1,PSMC1,GAB1,RRAGD,PRKAR1A,PRKAA2,RASA2,PRKAA1,PSMD7,ATP6V1E2,CALM3,PSMD10,DUSP5,FGF19,HDAC9,IGF1R,PRKCI,ERBB3,NCAM1,CAMK2G,MYO5A,PSMA5,RASGRF1,ADAM17,PSMB4,RAPGEF2,NR4A1,CALM1,PIK3R1,GRIN1,STRADB,YES1,BCAR1,PSMA4,EGFR,RASA1,GPLD1,GNAS,TSC1,INSR,PRKAG2,FGFR2,FGF18,RAB31,NR4A3,GRIN2D,NR4A2,GPER1,ATP6V1C1,JAK3,TBC1D4,CPEB2,DRD1 |
| 4.877e-04 | -7.63 | type 3 metabotropic glutamate receptor binding | molecular function | GO:0031800 | 4 | 4 | 16491 | 2452 |
CALM3,CALM2,CABP1,CALM1 |
| 4.882e-04 | -7.62 | pituitary-adenoma | COSMIC cancer mutations | pituitary-adenoma | 15 | 8 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,AKT1,PIK3CA,TP53,IDH1,EGFR |
| 4.882e-04 | -7.62 | skin-groin-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-groin-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | skin-foot-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-foot-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | GH | COSMIC cancer mutations | GH | 15 | 8 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,CDH1,RET,PIK3CA,PRKAR1A |
| 4.882e-04 | -7.62 | monophasic | COSMIC cancer mutations | monophasic | 15 | 8 | 17775 | 2585 |
RB1,SS18,CTNNB1,CDH1,PTEN,PIK3CA,TP53,EGFR |
| 4.882e-04 | -7.62 | skin-hand-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-hand-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | skin-shoulder-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-shoulder-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-monophasic | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-monophasic | 15 | 8 | 17775 | 2585 |
RB1,SS18,CTNNB1,CDH1,PTEN,PIK3CA,TP53,EGFR |
| 4.882e-04 | -7.62 | meninges-meningioma-anaplastic | COSMIC cancer mutations | meninges-meningioma-anaplastic | 15 | 8 | 17775 | 2585 |
CDKN2C,NF2,AKT1,PTEN,SMO,PIK3CA,IDH1,EGFR |
| 4.882e-04 | -7.62 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic | 15 | 8 | 17775 | 2585 |
RB1,SS18,CTNNB1,CDH1,PTEN,PIK3CA,TP53,EGFR |
| 4.882e-04 | -7.62 | skin-vulva-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-vulva-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | skin-chest-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-chest-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | skin-ear-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-ear-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | skin-lower_leg-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-lower_leg-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | pituitary-adenoma-GH | COSMIC cancer mutations | pituitary-adenoma-GH | 15 | 8 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,CDH1,RET,PIK3CA,PRKAR1A |
| 4.882e-04 | -7.62 | skin-adnexal_tumour-adenoid_cystic_carcinoma | COSMIC cancer mutations | skin-adnexal_tumour-adenoid_cystic_carcinoma | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.882e-04 | -7.62 | skin-axilla-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-axilla-adnexal_tumour-malignant_adnexal_tumour | 15 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 4.899e-04 | -7.62 | organ maturation | biological process | GO:0048799 | 18 | 9 | 16441 | 2455 |
BMP2,RHOA,FAT4,SEMA4D,ANO6,RET,DCHS1,PHOSPHO1,GATA3 |
| 4.899e-04 | -7.62 | centrosome localization | biological process | GO:0051642 | 18 | 9 | 16441 | 2455 |
SUN2,ASPM,SYNE2,DLG1,EZR,AURKA,NDE1,NUBP1,NIN |
| 4.926e-04 | -7.62 | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP | 168 | 41 | 17758 | 2588 |
TXN,DYRK3,SOD2,IL18,CD274,OSR2,PHF1,DUSP5,ICAM1,RND1,IER3,BTG3,E2F7,FJX1,DRAM1,SELK,RPGR,DUSP1,HES1,B3GNT2,RIPK2,PLAUR,RAPGEF2,PTGER4,PIM3,SAV1,CDK1,CD83,SOCS3,PTGS2,FAM177A1,ETS2,AREG,MFSD2A,NFKBIA,RAP2C,NFKBIZ,HS3ST3B1,EFNA1,PLD1,MAFF |
| 4.946e-04 | -7.61 | GCCNNNWTAAR_UNKNOWN | MSigDB lists | GCCNNNWTAAR_UNKNOWN | 142 | 36 | 17758 | 2588 |
IER5L,INPPL1,GGA1,KLC2,ETV5,NDRG2,TRIB2,PDGFB,DUSP5,CDKN2C,FOXP2,KCTD15,VASP,ITGA3,RALGPS2,NECAB3,BHLHE41,TOX2,MITF,CDKN1B,STK35,EPB41L5,HPS3,BCL9,CBX6,SFXN5,FYN,PEX5,ITPR1,MPP2,FAM117A,PITPNA,C1orf43,ABCA1,CTDSP1,DMPK |
| 4.946e-04 | -7.61 | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | MSigDB lists | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | 142 | 36 | 17758 | 2588 |
CCNC,LTBP1,DYRK3,CDK17,TMEM184B,FLOT1,TXNDC9,DUSP5,ICAM1,DNAJB9,RB1,SPP1,SLC16A6,IL6ST,ZFP36,DAPK1,BCL6,SGK1,HSPA13,PIM1,MX1,TGIF1,PLSCR1,LITAF,STK17B,MAP1B,SOCS3,MAPKAPK2,WIPI1,MYLK,FAM3C,NMI,STAT1,ARFGAP3,MAFF,IRF1 |
| 4.955e-04 | -7.61 | ACTIVATION_OF_JNK_ACTIVITY | MSigDB lists | ACTIVATION_OF_JNK_ACTIVITY | 15 | 8 | 17758 | 2588 |
KIAA1804,MAP3K11,MAP3K9,MDFIC,PKN1,MAP3K5,MAP3K6,MDFI |
| 4.955e-04 | -7.61 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | MSigDB lists | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | 15 | 8 | 17758 | 2588 |
PLK1,WEE1,CCNA2,PKMYT1,CCNB1,CCNB2,CDC25C,CDK1 |
| 5.009e-04 | -7.60 | RPS14_DN.V1_UP | MSigDB lists | RPS14_DN.V1_UP | 184 | 44 | 17758 | 2588 |
ANXA3,ARHGEF3,SDC4,ARL4C,KCTD12,RASGRP3,GDF15,EGR3,CACNB4,KBTBD11,SIRPA,EPS8L2,PDGFA,SPP1,FRY,GNB5,CAPG,BCL6,CD9,ATP8B1,SORL1,ACTA2,MDFIC,PDE4D,PTPRE,GFI1,IL1RAP,SCN3A,CYP1B1,MX1,PTGER4,CYFIP2,SESN1,ALCAM,STX3,RHOB,FUCA1,PROM1,RBM47,RCBTB2,PLK2,NR4A3,RAB31,SLC31A2 |
| 5.009e-04 | -7.60 | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | MSigDB lists | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | 184 | 44 | 17758 | 2588 |
KLF2,LGALS3,CUL1,RAB6A,PHLPP1,WWP2,SGPL1,WEE1,ANK1,HSF2,DACT1,NEK2,KIF22,RFX5,NFU1,LRIF1,GFPT1,ALDH2,CD55,CRIP2,EMP3,ERBB2IP,RAD17,IDH1,CYB5A,CRISPLD2,MAN2A2,DCAF10,SERTAD2,FNTA,PPP2R5A,HPSE,WDR11,SERPINA1,RAB11FIP2,PLK2,PKD2,WDR91,IFIH1,SLC31A2,CHPT1,SERPINB1,RTN3,AHR |
| 5.009e-04 | -7.60 | ESC_V6.5_UP_LATE.V1_UP | MSigDB lists | ESC_V6.5_UP_LATE.V1_UP | 184 | 44 | 17758 | 2588 |
PRSS8,FARP1,BVES,NDRG1,CTDSPL,NENF,PJA2,SEPP1,TSPAN7,PARM1,ARHGEF16,CYP26A1,BMP2,RNF128,IMPAD1,GPC3,OPN3,TINAGL1,LGMN,EGLN3,MYLIP,SGCE,CD55,CAPN6,SLC39A8,TMEM98,KDELR3,PRICKLE1,LOXL2,LCP1,TCN2,PITX2,PDLIM3,H1F0,PLOD2,P4HA2,ARFGAP3,SAMD8,EFNA1,UNC5B,SLC27A3,FOXA1,OCLN,FAM134B |
| 5.041e-04 | -7.59 | PID_RHOA_REG_PATHWAY | MSigDB lists | PID_RHOA_REG_PATHWAY | 46 | 16 | 17758 | 2588 |
ARHGEF3,FARP1,ARAP3,RHOA,ARHGEF11,ARHGDIB,ABR,ARHGAP35,ARHGEF10L,PLEKHG6,MCF2L,ARAP1,CDKN1B,ARHGAP4,DEF6,NGEF |
| 5.041e-04 | -7.59 | SIG_BCR_SIGNALING_PATHWAY | MSigDB lists | SIG_BCR_SIGNALING_PATHWAY | 46 | 16 | 17758 | 2588 |
AKT1,INPP5D,PIK3R1,FLOT1,CR2,ITPR2,ITPR3,DAG1,CD22,ITPR1,PLCG2,PIK3CA,PIK3CD,CD81,FLOT2,SYK |
| 5.061e-04 | -7.59 | WGTTNNNNNAAA_UNKNOWN | MSigDB lists | WGTTNNNNNAAA_UNKNOWN | 512 | 102 | 17758 | 2588 |
EMX1,PAX6,SPC25,GPR107,HOXB7,MCCC1,RASGRP3,TEX2,SLC20A1,PDGFB,MOCS1,CYP26A1,CDK14,IER3,CDKN2C,SHC3,CDKL5,RGS3,LMO4,XYLT2,ALDH1A3,KLF3,MITF,BCL6,MANF,RASGEF1A,TIMP2,MARK1,CAPN6,ASXL1,SYNE2,KIF13A,ROR1,ANLN,TMTC2,LDB2,SP4,COL12A1,EBF2,FZD7,HOXA9,STK38,MAOA,NRG1,KLF5,ZC3HC1,HOXC13,CTDSP1,IGFBP6,KLHL13,POC1B,ETV5,FLOT1,DHRS3,TNFRSF19,PPP2R3A,SIRPA,H1FX,MECOM,GBX2,HDAC9,FOXP2,DTX3L,SH3D21,IGF1R,GNB5,ADRBK1,GATA2,CALD1,TOX2,SGK3,TFAP2A,ZRANB1,NCAM1,GAD1,PSMA5,TGIF1,CASK,HMGN5,OXR1,PIK3R1,MBNL3,FNDC3A,FOS,NFIB,C3orf58,MAP1B,PRDX4,EPN3,PTPRF,PITX2,ETS2,AMMECR1,NR4A3,RHOBTB2,NR4A2,DRP2,SHOX2,RPS6KA3,FOXA1,KLF7,JARID2 |
| 5.096e-04 | -7.58 | negative regulation of neuron apoptotic process | biological process | GO:0043524 | 134 | 35 | 16441 | 2455 |
GCLM,PINK1,CPEB4,GRIK2,SOD2,NES,BCL2L1,SIX4,TP73,KIF14,MSH2,PIK3CA,BAX,PRKCI,ERBB3,LGMN,F2R,SOD1,RHOA,GCLC,OXR1,GRIN1,ILK,RASA1,OPTN,MDK,FYN,HTT,BHLHB9,AXL,WFS1,NR4A3,NR4A2,UNC5B,FAM134B |
| 5.099e-04 | -7.58 | oxoacid metabolic process | biological process | GO:0043436 | 984 | 184 | 16441 | 2455 |
ACACB,SLC35D2,UGT8,HSPG2,AGRN,AASS,CRYM,CPT2,HEXB,MCCC1,VARS2,PLA2G16,OAT,SDC1,ECI1,CHST2,CHPF,CYP1A1,P4HB,CYP2S1,IMPAD1,ALDH1A3,PAPSS1,SLC46A1,SERINC2,ACOX2,TECR,CYP1B1,CCBL2,PRKAR2B,ICMT,IDH1,MRPS36,PNKD,CYP4F3,POR,HS6ST1,ENPP1,HPSE,UEVLD,P4HA2,IARS2,DHTKD1,ADIPOR1,PPP2R5D,PDPR,HS6ST3,DLAT,PRKAA2,FAM213B,ALDH6A1,DHPS,CYP2J2,ELOVL7,PRKAA1,ASL,SLC1A3,B4GALT4,PDXDC1,GNS,PFKL,CTPS1,PCYOX1,AHCY,ACAD8,GAD1,MCCC2,ABCC1,CYP26B1,CHSY3,GFPT1,FADS2,PRODH,B3GNT7,ERO1A,PDK3,PKM,AMDHD1,CYB5A,GLCE,MAPKAPK2,SLC6A6,PRKAG2,FA2H,HTT,FAAH,MDH1,B4GAT1,EGLN1,PLA2G4A,PAPSS2,UGP2,XYLT1,MGST2,SLC7A2,LPIN3,EXT2,CYP39A1,CYP26A1,PER2,XYLT2,FABP6,SRR,GOT1,APIP,ACSL4,ETHE1,MINPP1,EGLN3,SULT2B1,SULF2,GPX4,CTH,PFKFB2,PANK1,ACO1,GLO1,PXYLP1,PDHX,PTGS2,ALDH5A1,ABHD12,ACAD10,PEX2,SLC27A1,CYP2U1,HS3ST3B1,B4GALT3,LTA4H,SLC27A3,ST3GAL1,NDST3,CMAS,GCLM,ENO2,GCAT,SCD5,HAL,GNE,SDC4,CRABP2,DSE,SPR,SGPL1,SLC27A6,GPC3,GALNS,ECI2,ATP8B1,HMGCL,ABCD1,ALDH7A1,SYK,NCOA2,CRTAP,MYO5A,FAH,B3GALT6,PCCB,PGM1,B3GNT2,SHMT1,PLSCR1,GCLC,ELOVL3,OGDHL,PPARA,GGH,RNPEP,PRDX4,DDAH1,MARC1,CTNS,ACADSB,SLC35B3,PLA2G15,NR4A3,CSGALNACT1,GLB1,ACADM,ARSB,PTGES,OCLN,ACOT7 |
| 5.100e-04 | -7.58 | YIH_RESPONSE_TO_ARSENITE_C1 | MSigDB lists | YIH_RESPONSE_TO_ARSENITE_C1 | 22 | 10 | 17758 | 2588 |
TOP2A,HSF2,ZFP36,NAT1,MYBL2,PIK3CA,CCNB1,RASA1,FAS,SGPL1 |
| 5.100e-04 | -7.58 | TACGGGT,MIR-99A,MIR-100,MIR-99B | MSigDB lists | TACGGGT,MIR-99A,MIR-100,MIR-99B | 22 | 10 | 17758 | 2588 |
CYP26B1,AP1AR,CTDSPL,SLC44A1,KBTBD8,HS3ST3B1,TRIB2,ICMT,EPDR1,RAVER2 |
| 5.100e-04 | -7.58 | SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN | MSigDB lists | SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN | 22 | 10 | 17758 | 2588 |
CCNA2,CDC20,KIF23,AURKA,KIF22,CCNB1,CCNF,UBE2C,CDC25C,CKS2 |
| 5.107e-04 | -7.58 | PDZ | pfam domains | PF00595 | 128 | 34 | 16629 | 2504 |
LMO7,FRMPD3,USH1C,ARHGEF11,MPP5,APBA1,SLC9A3R2,PICK1,SNTA1,RGS12,RGS3,DLG1,TAX1BP3,DLG3,MAST4,TIAM1,DVL2,CASK,RAPGEF2,SNTB2,MPP1,PARD3B,SCRIB,ERBB2IP,SNTB1,RHPN1,PDLIM3,GRID2IP,TJP3,SHROOM3,LIMK1,MPP2,APBA2,SHROOM2 |
| 5.131e-04 | -7.58 | IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) | protein interactions | 3551 | 136 | 37 | 16036 | 2547 |
ACVR1,NLRX1,TRAF2,SLC25A13,TP53,CUL1,TGFBR1,TP73,IRAK1,CTNNB1,PRKCI,TRIM21,PPP1CA,MAP3K7,NFKB2,EGLN3,DUSP1,MAP3K3,PLK1,AKT1,SHARPIN,PYGL,TFAP2C,PRKCQ,CD40,BCL10,NCOA3,TSC1,HTT,PRDX3,NFKBIA,MAP3K11,NLRC5,AURKA,PPP2R3C,HSPB1,NR2C2 |
| 5.131e-04 | -7.58 | MHC_I_C | pfam domains | PF06623 | 4 | 4 | 16629 | 2504 |
HLA-B,HLA-C,HLA-E,HLA-A |
| 5.132e-04 | -7.57 | LIU_SOX4_TARGETS_UP | MSigDB lists | LIU_SOX4_TARGETS_UP | 132 | 34 | 17758 | 2588 |
LASP1,ILDR1,TMEM184B,SOX9,DUSP5,EPDR1,PDGFA,CES2,METTL7A,ENPP5,FUT8,TMEM143,SORL1,RP2,LGMN,ARL4D,IL10RB,THRB,ENPP4,ELK3,MBP,USP31,PRSS23,LHFPL2,EGFR,BCL10,SWAP70,CSF1,PLK2,WWTR1,RYK,TLE1,PPP1CB,USP43 |
| 5.141e-04 | -7.57 | REACTOME_SIGNALING_BY_ERBB2 | MSigDB lists | REACTOME_SIGNALING_BY_ERBB2 | 97 | 27 | 17758 | 2588 |
AKT1,NR4A1,CALM1,CASP9,PIK3R1,CALM3,NRG2,ERBB2,PRKAR2B,YES1,ITPR2,ITPR3,PHLPP1,PRKACA,CDK1,EGFR,CALM2,PLCG1,FYN,ADRBK1,PTEN,PIK3CA,CDKN1B,NRG1,ERBB3,GAB1,PRKAR1A |
| 5.200e-04 | -7.56 | HSPA4 (heat shock 70kDa protein 4) | protein interactions | 3308 | 312 | 72 | 16036 | 2547 |
ST13,NQO1,NF2,EPAS1,NDRG1,THRA,DNAJC3,XIAP,TP53,CUL1,DNAJB11,ERBB2,MORF4L2,HDAC6,PHLDA1,DENND2D,APPBP2,KMT5C,ZFP36,PSMC2,TUBG1,PPP1CA,APOBEC3G,THRB,PLK1,SIRT1,MAP3K3,SEC23A,BAG4,SOD1,AKT1,EZR,CD40,CBL,CDC25C,CDK1,VCP,DNAJC10,PTGS2,LIMK1,FAM114A1,MAP3K11,PPP1CB,HDAC1,KPNA2,HSPB1,NR3C2,PINK1,DNAJB2,PRKAA1,ASB9,PSMD10,TGFBR1,TEAD3,IRAK1,PPP1R10,BAX,SGK1,H2AFY,TAGLN2,PIM1,MAPK7,PPP6R1,DUSP1,HES1,PRSS23,AMFR,NUB1,CALM1,EGFR,HTT,MAP3K5 |
| 5.203e-04 | -7.56 | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP | MSigDB lists | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP | 127 | 33 | 17758 | 2588 |
LASP1,NUAK1,FAM129B,SERPINB9,GMPR,SEPT4,ETS1,TMCC3,CDK14,OTUD1,BMP7,MCF2L,RGS5,CPD,FBLN5,NR3C1,LITAF,EMP3,LCP1,COL12A1,NFIX,CAMK2N2,SMTNL2,LRIG1,MATN2,SIPA1L1,FAM110C,PRKCDBP,LRRK1,RPL22,PKIA,FGD1,RGMA |
| 5.206e-04 | -7.56 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 179 | 43 | 17758 | 2588 |
ST13,ARMCX3,NFKBIE,CAPN12,ATP9A,NDRG1,RASSF7,SOD2,CCDC68,SLC36A4,TGFBR1,ICAM1,HMGXB4,DNAJB9,M6PR,CALR,SETDB2,FAM46A,MGAT1,P4HB,PFKL,VAT1,HSPA13,PDE4D,DVL2,SULF2,SNX8,P2RX4,LGALS8,ITCH,HMG20B,LRRC1,SAV1,TXNDC11,UAP1,ITPR1,PIK3C2B,ATP6V1C1,WDR91,TANC2,ABCA1,MAFF,SNPH |
| 5.208e-04 | -7.56 | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP | 195 | 46 | 17758 | 2588 |
FRMD4A,NLRX1,POC1B,SOX9,HABP4,GPR180,NUDT12,SLC25A35,CCDC92,CAPN2,C16orf59,TMEM87B,RNF128,AIM1,FAM63A,ABCD1,RP2,KLF9,AK3,DLG3,CNOT6L,MGAT5,MYO5A,SLC5A11,ERLEC1,TACC1,TEF,RNF165,PARP4,FBXO8,PRICKLE1,PRRC1,C15orf39,STK17B,FZD7,CMTM7,KDSR,SLC6A6,CTNS,RBM47,WDR11,CCDC6,MDH1,ALG2,TMEM120A,MAPK12 |
| 5.208e-04 | -7.56 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | 195 | 46 | 17758 | 2588 |
SEMA6B,HECA,AVPI1,PAPSS2,SSH1,EPAS1,NUAK1,XYLT1,CTDSPL,ARL4C,OAT,STIL,NCS1,LMNA,SGPL1,SLC16A6,PAQR5,PPP4R1,COL6A1,OPN3,CD9,NOTCH3,PDE4D,TIPARP,ITM2C,RIMS2,CERS2,PDGFC,PGM1,MMD,CASP9,BNIP3L,SOCS3,GABARAPL1,IL1R1,WIPI1,PLK2,NR4A3,MAOA,ALPK3,MAPK13,PLXND1,LTBP2,ZMIZ1,RTN3,JARID2 |
| 5.225e-04 | -7.56 | DER_IFN_BETA_RESPONSE_UP | MSigDB lists | DER_IFN_BETA_RESPONSE_UP | 102 | 28 | 17758 | 2588 |
ELK4,MX1,TRAPPC10,PLSCR1,IQGAP1,HLA-E,PLAUR,PARP4,TAP1,PSME1,IFIT3,PHLDA1,HLA-A,MAP1B,ATP6V0B,BTG1,ETS2,PLOD2,CALD1,NMI,STAT1,IRF2,TRIM21,IFIT1,HLA-C,PDXK,IFI6,IRF1 |
| 5.233e-04 | -7.56 | MODULE_69 | MSigDB lists | MODULE_69 | 489 | 98 | 17758 | 2588 |
LMO7,ACVR1,AASS,MRPS15,TSC22D3,PNPLA2,TP53,GATA3,NDRG2,MAPK4,CCNL1,NANS,BAIAP3,BARD1,CMTM6,C1orf116,TYMP,RNF220,CYP1A1,ESPN,PDE4D,SCARA3,TUBA4A,ATG4D,TDP1,TCEB2,SNTB2,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRIM7,KDM4D,AMZ2,ENPP1,PI4K2B,PTGS2,NEIL1,MPRIP,SLC9A6,PLEKHG1,PPP1CB,RNASEL,PCSK5,RRAGD,LMTK3,CDH22,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,TFAP4,C9orf69,RALGPS2,CDK16,TMEM62,UBE2J1,CD9,PIKFYVE,FAR2,CITED2,ITM2C,EEF1D,ABCC1,MOB4,AMOTL2,HMGN5,TBC1D8B,FMN1,ADCK3,MICB,FURIN,PIP4K2C,MYBL2,DIAPH2,SRSF5,BCL2L13,FOS,EGFR,BSDC1,RHPN1,USP6,GALNT3,PTPRF,CD8A,PROM1,FGFR2,CSF1,WDR19,S100A5,FGD6,NXPH4,TMEM120A,C17orf75,PKIA,EGLN1 |
| 5.233e-04 | -7.56 | actin filament organization | biological process | GO:0007015 | 175 | 43 | 16441 | 2455 |
WASF3,INPPL1,SORBS1,USH1C,HSP90B1,ADD1,TMSB15A,EPS8,SORBS3,MICALL2,FAM101B,EMP2,TMSB15B,CORO1B,RND1,RAC2,ZYX,VASP,PDCD10,FRY,FRYL,DLG1,PRKCI,ESPN,CTTN,PACSIN1,RHOA,FMN1,DSTN,DMTN,EZR,DIAPH2,BCAR1,LCP1,DPYSL3,SWAP70,PDLIM3,ARAP1,ARRB1,TMOD2,ARPC2,SHROOM2,COBL |
| 5.233e-04 | -7.56 | aminoglycan metabolic process | biological process | GO:0006022 | 175 | 43 | 16441 | 2455 |
SLC35D2,AGRN,PAPSS2,HSPG2,IL15,XYLT1,HEXB,SDC4,B4GALT4,DSE,SDC1,EXT2,CHST2,CHPF,GNS,GPC3,IMPAD1,XYLT2,PAPSS1,GALNS,PIM1,CHP1,HMMR,CHSY3,B3GALT6,B3GNT7,B3GNT2,AKT1,GUSB,PXYLP1,GLCE,FUCA1,HS6ST1,HPSE,SLC35B3,CSGALNACT1,GLB1,B4GAT1,HS3ST3B1,B4GALT3,ARSB,ST3GAL1,NDST3 |
| 5.240e-04 | -7.55 | receptor binding | molecular function | GO:0005102 | 1429 | 256 | 16491 | 2452 |
TRIM24,TAP1,GATA3,NRG2,IL18,SYTL4,CCNB1,CMTM6,PICK1,GRM5,CALM2,TYMP,TGFBR3,MUC4,CTGF,ELMO2,CABP1,DNM2,MANF,SEMA3G,ACOX2,TIAM1,CPE,ARF4,PGF,PLCG1,ENPP1,AREG,PPP2R4,BMP1,F2RL1,SEMA6B,HLA-E,ITGA6,ZNRF3,MESDC2,MARCH8,CALR,ITGA3,CYR61,CD70,ULBP2,SYTL3,SOCS5,TRAK2,UFD1L,MICB,CALM1,FHL2,ILK,KDM3A,GNA11,RASA1,IL1R1,NCOA3,FNTA,ETS2,HTT,SEMA4D,RAET1L,ARAP1,PIAS2,NR4A2,EFNA1,GDF11,SPRED1,TUBB4B,TNFSF9,NOV,SP100,DOK4,DAB2IP,PDE4D,DLG3,FLOT2,MED30,TMBIM1,SEMA3B,DOCK4,RIPK2,DMTN,UTRN,CBL,ALCAM,FZD7,GABARAPL1,CMTM7,IRS2,FYN,JAK1,NGFRAP1,SIPA1L1,STAT1,NRG1,ARNT,NUDT6,CTHRC1,PLSCR4,NKX3-1,HSP90B1,TRAF2,PKN1,FGF19,EFNB1,SRPX2,ICAM1,HLA-A,RND1,CXCL16,IRAK1,ANKS1B,PTEN,CD9,ADAM15,ECI2,CNPY3,NCOA2,OSGIN1,PVRL4,RASGRF1,PDGFC,CASK,PLSCR1,RAPGEF2,PIK3R1,GRIN1,DIAPH2,YES1,TXK,LDLRAP1,DBI,FAM3C,ERAP1,HMGA1,CD81,RGMA,TNK1,CASP3,EPHA4,NENF,DNER,PDGFB,SLC9A3R2,TRIM68,PCNA,RABEP2,CTNNB1,P4HB,SHC3,NPNT,SIVA1,IL6ST,DLG1,ARNT2,IL1RAP,S100A13,SMAGP,ASXL1,ITCH,IDH1,VCP,MDK,GPRC5B,WIPI1,MADD,CTNND1,GLA,GRN,SERPINE2,HLA-F,CALM3,TEC,FBLN1,BMP2,SPP1,RB1,IGF1R,TIMP1,ICAM5,NPTN,WNT3A,LRIF1,CDK5R1,GNAS,INSR,PVRL2,CSF1,PLPP3,EGFL7,JAK3,SEMA3A,RARG,COL16A1,APOL2,TOB1,DRD1,GAS2L1,SORBS1,NF2,IL15,TP53,ERBB2,P2RX7,EMP2,BCAP31,SYTL2,ARHGEF16,PDGFA,ARTN,TACC2,REEP1,SMO,F2R,DVL2,FRS3,SIRT1,TIMP2,S100A4,ERBB2IP,TAPBP,PTPRJ,IDE,SECTM1,EFNA5,ABCA1,LIFR,CMTM4,ARHGEF11,MACC1,GNAL,LRP4,GDF15,TGFBR1,HMGN3,JAG2,AIP,ADRBK1,ADORA1,BMP7,HMGCL,SYK,P2RX4,FBLN5,ADAM17,WNT10B,GUSB,PLAUR,CD8A,HLA-B,SCG2,FGF18,NETO2,ARRB1,PKD2,ICOSLG,L1CAM |
| 5.266e-04 | -7.55 | REACTOME_METABOLISM_OF_CARBOHYDRATES | MSigDB lists | REACTOME_METABOLISM_OF_CARBOHYDRATES | 233 | 53 | 17758 | 2588 |
GALK1,SLC2A4,UGP2,AGRN,ENO2,HSPG2,SLC25A13,SDC4,HEXB,CALM3,DSE,B4GALT4,SDC1,PRKACA,EXT2,CHST2,CHPF,GNS,CALM2,NUP210,PFKL,GPC3,GYS1,GOT1,PHKA2,PHKG2,NUP85,HMMR,CHSY3,B3GALT6,B3GNT7,PGM1,B3GNT2,PFKFB2,GUSB,CALM1,MGAM,PYGL,GLCE,HS6ST1,HPSE,PRPS2,CSGALNACT1,GLB1,MDH1,HS3ST3B1,B4GALT3,NUP37,ARSB,ST3GAL1,PPP2R5D,NDST3,HS6ST3 |
| 5.270e-04 | -7.55 | REGULATION_OF_APOPTOSIS | MSigDB lists | REGULATION_OF_APOPTOSIS | 339 | 72 | 17758 | 2588 |
CASP3,ACVR1,XIAP,TP53,CUL1,BCL2L1,AIFM2,BARD1,IER3,TP73,DAPK2,CDKN2C,SIVA1,BCL6,CDKN1B,TNFRSF18,F2R,CDKN2D,MX1,BAG4,SOD1,ACVR1C,CASP9,BNIP3L,HTATIP2,GLO1,STK17B,CDK1,CASP4,VCP,SOCS3,MADD,STAT1,HDAC1,AIFM3,HSPB1,CBX4,HSP90B1,CTSB,DAP,BIK,SERPINB9,NOTCH2,ADAMTSL4,GSTP1,CALR,TOP2A,CARD8,ADORA1,IGF1R,PTEN,BAX,DAPK1,CD70,PIM1,ERCC2,TMX1,GCLC,RUNX3,BCAR1,CDK5R1,RASA1,BCL10,STK17A,FAS,BTG1,SCG2,HTT,SEMA4D,MAP3K5,HIPK3,IFI6 |
| 5.270e-04 | -7.55 | INS (insulin) | protein interactions | 3630 | 24 | 11 | 16036 | 2547 |
RB1,NOV,INSR,IDE,IGF1R,CTSB,RGS20,SYTL4,CTSD,CPE,HSPB1 |
| 5.270e-04 | -7.55 | DGKZ (diacylglycerol kinase, zeta) | protein interactions | 8525 | 24 | 11 | 16036 | 2547 |
SNTA1,RB1,PLCG1,RBL1,SNTB2,SAT1,PIK3CA,ARRB1,SNTB1,LEPR,RASGRP1 |
| 5.276e-04 | -7.55 | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | MSigDB lists | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | 107 | 29 | 17758 | 2588 |
HMMR,CHSY3,B3GALT6,B3GNT7,B3GNT2,AGRN,HSPG2,GUSB,SDC4,HEXB,DSE,B4GALT4,SDC1,EXT2,CHST2,GLCE,CHPF,GNS,HS6ST1,HPSE,GPC3,CSGALNACT1,GLB1,HS3ST3B1,B4GALT3,ARSB,ST3GAL1,NDST3,HS6ST3 |
| 5.276e-04 | -7.55 | BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP | 107 | 29 | 17758 | 2588 |
ARHGEF3,MPZL1,ST14,SOX9,F11R,NTAN1,DDR1,LBR,LMNA,MYO5C,TMEM63A,SOX13,PDGFA,NCOA3,ST5,TJP3,LLGL2,CDK19,MATN2,SPINT2,ZNF165,TAX1BP3,MAPK13,EPHB4,CACNA1D,B4GALT3,KCTD3,ATP2B1,SEPHS1 |
| 5.276e-04 | -7.55 | DOANE_BREAST_CANCER_ESR1_UP | MSigDB lists | DOANE_BREAST_CANCER_ESR1_UP | 107 | 29 | 17758 | 2588 |
SSH3,RET,SYBU,GATA3,GDF15,GALNT7,DUSP4,ALCAM,RHOB,RND1,SCNN1A,TJP3,ACADSB,MLPH,AREG,DHRS2,SLC16A6,NAT1,TMC5,C1orf21,INPP4B,ANXA9,ACOX2,CACNA1D,TSPAN1,MAST4,FOXA1,CYBRD1,SEMA3B |
| 5.277e-04 | -7.55 | ITGA6 (integrin alpha 6) | protein interactions | 3655 | 35 | 14 | 16036 | 2547 |
BIN1,LGALS8,CD63,HLA-E,CD82,CALM1,MCOLN3,PDIA3,CANT1,HLA-C,B4GALT4,LGALS3BP,PICK1,PCSK5 |
| 5.277e-04 | -7.55 | ECH1 (enoyl-CoA hydratase 1, peroxisomal) | protein interactions | 1891 | 35 | 14 | 16036 | 2547 |
PEX5,PAFAH1B3,TIMP1,HTT,IQGAP1,SERPINB9,MCCC1,FHL2,ECI2,DNAJB11,CSTF2,MCCC2,EEF1D,SEPHS1 |
| 5.278e-04 | -7.55 | proteoglycan metabolic process | biological process | GO:0006029 | 95 | 27 | 16441 | 2455 |
CHSY3,B3GALT6,AGRN,HSPG2,XYLT1,HEXB,SDC4,PXYLP1,DSE,SDC1,FOXL1,EXT2,CHPF,GLCE,BMP2,HS6ST1,HPSE,IMPAD1,XYLT2,GPC3,CSGALNACT1,CANT1,HS3ST3B1,ARSB,NDST3,HS6ST3,SULF2 |
| 5.281e-04 | -7.55 | V$AP1_Q6_01 | MSigDB lists | V$AP1_Q6_01 | 255 | 57 | 17758 | 2588 |
SEMA6B,LRRFIP2,CAPN12,HSPG2,NUAK1,PSMD7,PRSS22,ZNF385B,LMNA,ZFYVE9,PAK6,FAM46A,IRAK1,NECAB3,ABCA2,VAT1,SGK1,ABCD1,TAGLN2,PIM1,SNX10,TBC1D10B,TUBA4A,MDFI,TRAK2,SMARCA2,TRIM8,CASK,MCTP1,ELK3,LONRF3,CAPN6,CTNNAL1,DENND1B,PTPRH,RGAG1,KBTBD8,IGSF8,CAPNS1,KDM3A,ZFAND5,GABARAPL1,EPN3,TRIM47,TBC1D17,MPRIP,MAP2,S100A5,PRKCDBP,CAB39,FBXO44,RCAN2,EFNA1,STARD13,TOB1,SNPH,DMPK |
| 5.296e-04 | -7.54 | REACTOME_TOLL_RECEPTOR_CASCADES | MSigDB lists | REACTOME_TOLL_RECEPTOR_CASCADES | 112 | 30 | 17758 | 2588 |
SIGIRR,UNC93B1,HSP90B1,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CTSB,PELI3,DUSP4,ELK1,FOS,CDK1,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,PLCG2,DNM2,NOD2,MAPK11,IRF7,MAP3K7,LGMN,MAPK7,NFKB2,CNPY3,PPP2R5D,RPS6KA3 |
| 5.340e-04 | -7.54 | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_UP | 64 | 20 | 17758 | 2588 |
PPIF,GALK1,ADD1,IGFBP6,ADO,TMX4,SAT1,MYBL2,ERBB2,AES,MDK,PGF,CDK16,FBXL14,STAT1,TRIM21,ERCC2,CBX4,SRSF9,EPHX1 |
| 5.340e-04 | -7.54 | CASTELLANO_NRAS_TARGETS_UP | MSigDB lists | CASTELLANO_NRAS_TARGETS_UP | 64 | 20 | 17758 | 2588 |
SERPINE2,NQO1,PQLC3,TMEM43,USP18,CRIP2,TAP1,KCTD12,IL13RA1,FNDC3A,CRABP2,MEST,SDC1,AIM1,STAT1,BAX,IFIT1,ACADM,IFIH1,EPHX1 |
| 5.344e-04 | -7.53 | MODULE_179 | MSigDB lists | MODULE_179 | 431 | 88 | 17758 | 2588 |
ACVR1,AASS,MRPS15,TP53,IL13RA1,MAPK4,CCNL1,NANS,BAIAP3,CMTM6,C1orf116,CYP1A1,RNF220,METTL7A,PAQR5,ESPN,EPB41L4B,PDE4D,SCARA3,GM2A,TUBA4A,ATG4D,TMCC2,TDP1,TCEB2,LAP3,SLC39A8,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRIM7,KDM4D,AMZ2,PTGS2,PI4K2B,NEIL1,MPRIP,PLEKHG1,PPP1CB,RNASEL,RRAGD,LMTK3,CDH22,FAM169A,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,LGALS3BP,DNAJB9,C9orf69,CDK16,TMEM62,CITED2,FAR2,FAIM,CNOT6L,ITM2C,EEF1D,MOB4,AMOTL2,HMGN5,TBC1D8B,FMN1,ADCK3,MICB,PIP4K2C,FURIN,BCL2L13,FOS,BSDC1,PTPRF,FUCA1,CD8A,TIMP3,CSF1,WDR19,S100A5,FGD6,NXPH4,MAL2,GEM,TMEM120A,C17orf75,PKIA |
| 5.378e-04 | -7.53 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5 | 9 | 6 | 17758 | 2588 |
NR4A2,NFKBIZ,EGLN3,FOS,NR4A1,PTGER4 |
| 5.378e-04 | -7.53 | FOCAL_ADHESION_FORMATION | MSigDB lists | FOCAL_ADHESION_FORMATION | 9 | 6 | 17758 | 2588 |
TESK2,TSC1,TAOK2,SORBS1,PTEN,ACVRL1 |
| 5.382e-04 | -7.53 | SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | 78 | 23 | 17758 | 2588 |
CLCN3,RET,BIK,CCNO,GATA3,ASAH1,COL4A5,NPDC1,ALCAM,CDS1,DCAF10,CXXC4,TJP3,RBM47,MLPH,IL6ST,ITPR1,TTC9,ERBB3,RAB27B,MAST4,FOXA1,MCCC2 |
| 5.385e-04 | -7.53 | C2 | prosite domains | PS50004 | 108 | 30 | 11866 | 1802 |
PLA2G4A,DOC2A,MCTP1,ITCH,RASA2,MCTP2,ESYT1,BAIAP3,SYTL4,RASA1,SYTL2,ABR,PLCG1,CPNE2,PLCH1,SYT7,RAB11FIP2,RGS3,RIMS3,PLCG2,RAB11FIP1,DYSF,WWP1,PIK3C2B,SYT13,PLCB2,SYTL3,TC2N,RIMS2,ESYT2 |
| 5.403e-04 | -7.52 | Neurotrophin signaling pathway | KEGG pathways | hsa04722 | 120 | 33 | 6908 | 1076 |
SORT1,NFKBIE,RPS6KA1,TP53,CALM3,TP73,CALM2,RPS6KA2,IRAK1,SHC3,PLCG2,BAX,PIK3CA,MAPK11,PIK3CD,MAPK7,CAMK2G,MAP3K3,RHOA,RIPK2,AKT1,CALM1,PIK3R1,ARHGDIB,MAPKAPK2,PLCG1,NGFRAP1,NFKBIA,MAPK13,MAP3K5,GAB1,RPS6KA3,MAPK12 |
| 5.403e-04 | -7.52 | Neurotrophin signaling pathway | KEGG pathways | ko04722 | 120 | 33 | 6908 | 1076 |
SORT1,NFKBIE,RPS6KA1,TP53,CALM3,TP73,CALM2,RPS6KA2,IRAK1,SHC3,PLCG2,BAX,PIK3CA,MAPK11,PIK3CD,MAPK7,CAMK2G,MAP3K3,RHOA,RIPK2,AKT1,CALM1,PIK3R1,ARHGDIB,MAPKAPK2,PLCG1,NGFRAP1,NFKBIA,MAPK13,MAP3K5,GAB1,RPS6KA3,MAPK12 |
| 5.405e-04 | -7.52 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN | 174 | 42 | 17758 | 2588 |
DDX58,UNC93B1,TMEM217,PARP14,TAP1,NDC80,HERC5,SORBS3,SAMD9,CD274,PATL2,HERC6,PGAP1,DUSP5,DTX3L,ZNF687,FAM46A,ANKS1B,TRIM21,IFIT1,OAS3,NFKB2,PARP9,REC8,MX1,TGIF1,SPATA18,PLSCR1,PAPD7,USP18,IFIT3,PRX,C19orf66,RAB11FIP1,NLRC5,NR4A3,IRF7,CMPK2,SLC31A2,IFIH1,IFI6,IRF1 |
| 5.408e-04 | -7.52 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | 153 | 38 | 17758 | 2588 |
KLF2,ARAP3,PAPSS2,NQO1,NDRG1,DNAJB2,ETNK1,HERC5,GDF15,JAG2,SLC1A3,SEPP1,DDR1,ADAMTSL4,PHLDA1,SIRPA,IL17RB,PDGFA,CYP1A1,VAT1,TIAM1,IL1RAP,RASGRP1,P2RX4,CPD,SOCS3,MAGED2,SLCO4A1,BTG1,SERPINA1,PLK2,HOXA9,STAT1,NETO2,PIK3C2B,HSPB1,IFI6,RRAGD |
| 5.414e-04 | -7.52 | actin binding | molecular function | GO:0003779 | 389 | 82 | 16491 | 2452 |
SORBS1,NF2,SSH1,ADD1,TMSB15A,MICALL2,HDAC6,SPTB,EPS8L2,PICK1,TMSB15B,PLS3,SCNN1A,CAPG,POF1B,ESPN,DIXDC1,RP2,MYH14,TLN2,MYRIP,NEB,MYO5B,SSH3,SYNE3,SNTB2,S100A4,DMTN,UXT,DSTN,SYNE2,UTRN,EZR,TNS1,BCL7B,ANLN,DAG1,LCP1,TNS4,MPRIP,SHROOM3,CORO1C,MYLK,TRIOBP,NOD2,TMOD2,SPTBN5,COBL,WASF3,LASP1,INPPL1,USH1C,EPS8,CORO1B,MYO5C,SNTA1,FLII,VASP,ADD3,CALD1,FXYD5,LIMCH1,CCDC88A,MYO5A,CTNNAL1,FMN1,CORO2A,DIAPH2,PLS1,AIF1L,SNTB1,ANTXR1,ABLIM2,EGFR,KLHL2,PLEKHH2,CLMN,ARPC2,SHROOM2,HOOK1,AFAP1,RUSC1 |
| 5.420e-04 | -7.52 | positive regulation of MAP kinase activity | biological process | GO:0043406 | 212 | 50 | 16441 | 2455 |
AVPI1,TAB3,TRAF2,EPHA4,PRKAA1,P2RX7,ERBB2,PKN1,PDGFB,FLT3,ERP29,DUSP5,TP73,BMP2,PDGFA,PDCD10,IRAK1,MAP3K9,DAB2IP,MAPK11,MDFIC,IQGAP3,MAP3K7,SYK,DVL2,RASGRP1,MDFI,SOD1,RIPK2,FZD4,MAPKAPK3,PDE5A,ILK,CD40,CDK1,MAP3K6,EGFR,MAPKAPK2,INSR,FGF18,MADD,KIAA1804,MAP3K11,NOD2,ARRB1,EFNA1,FZD5,MAP3K5,CD81,GAB1 |
| 5.429e-04 | -7.52 | regulation of neuron projection development | biological process | GO:0010975 | 365 | 78 | 16441 | 2455 |
FOXO6,SSH1,RET,EPHA4,GATA3,PLXNA1,CAMK1D,NCS1,CDKL5,DPYSL2,DNM2,DAB2IP,CTTN,SEMA3G,PACSIN1,TIAM1,SEMA3B,SSH3,AKT1,CDC20,KLK6,ULK2,ARHGAP35,DPYSL3,FYN,GPRC5B,BHLHB9,PTK7,LIMK1,PLK2,SIPA1L1,EFNA5,NRG1,RAB29,PLXND1,ITPKA,ARF6,COBL,LZTS1,GRN,SEMA6B,SERPINE2,CIT,LRP4,CRABP2,SPP1,ITGA3,PTEN,KIF13B,BMP7,MEGF8,KNDC1,KIAA0319,PRKCI,TNFRSF12A,NPTN,NTN1,WNT3A,GFI1,ITM2C,RIMS2,FAM134C,CCDC88A,RHOA,RAPGEF2,GRIN1,ILK,CDK5R1,MAP1B,PTPRF,SEMA4D,TMEM30A,EFNA1,ARSB,SHOX2,SEMA3A,L1CAM,NGEF |
| 5.433e-04 | -7.52 | GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN | 190 | 45 | 17758 | 2588 |
LASP1,SLC41A1,RASA2,TAP1,CAMK1D,MGST2,CDIPT,HERC6,PHF1,NFAT5,B4GALNT1,IRF2BPL,NUP210,SETDB2,UBE2J1,OAS3,TMEM64,MAPK7,S100A13,C9orf72,PARP9,DUSP1,DOCK4,SMARCA2,ARAP2,TIMP2,TNIP1,MAPKAPK3,FOXJ2,BNIP3L,ATP1B1,XKRX,NCOA3,RTN4RL1,ATXN7L3,DOLPP1,SLC25A40,LRIG1,MADD,TRIOBP,NR4A2,TOB1,RARG,JARID2,IRF1 |
| 5.433e-04 | -7.52 | GSE30083_SP2_VS_SP4_THYMOCYTE_UP | MSigDB lists | GSE30083_SP2_VS_SP4_THYMOCYTE_UP | 190 | 45 | 17758 | 2588 |
GAS2L1,EXPH5,LZTFL1,USH1C,MPZL1,VANGL1,AK7,ATP9A,ESRP1,MCOLN3,EPHX4,TDRKH,BCL2L1,CAMK1D,POMGNT1,RBP7,SPTB,SYTL2,NEO1,ELF3,ZNF823,ZCCHC12,TACC2,KCNN4,CEP78,GOT1,ALDH7A1,CTTN,ARMCX6,MED22,TUBA4A,HCN3,REC8,PKMYT1,CRISPLD2,LRRC42,MPP2,SLC27A1,STK39,DMWD,POMT1,ACOT7,PCSK5,PKD1L2,MAPK12 |
| 5.433e-04 | -7.52 | JAEGER_METASTASIS_UP | MSigDB lists | JAEGER_METASTASIS_UP | 42 | 15 | 17758 | 2588 |
SPP1,DDAH1,ENPP1,PAPSS2,PLOD2,TBC1D1,EPS8,AURKA,KIF2C,NCAM1,MERTK,H2AFV,GINS4,SMC4,CKS2 |
| 5.433e-04 | -7.52 | REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | MSigDB lists | REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 42 | 15 | 17758 | 2588 |
CCND1,CCNE2,CDK5RAP1,DIRAS3,CDKN2C,CDKN1C,PTEN,CKS1B,HERC5,HEXIM2,PKMYT1,CDKN2D,CDC25C,CDK5R1,CKS2 |
| 5.433e-04 | -7.52 | PID_ECADHERIN_STABILIZATION_PATHWAY | MSigDB lists | PID_ECADHERIN_STABILIZATION_PATHWAY | 42 | 15 | 17758 | 2588 |
CAMSAP3,ZYX,VASP,RHOA,IGF1R,CTNNB1,CDH1,PVRL2,PLEKHA7,CTNND1,EFNA1,NCKAP1,CYFIP2,ARF6,EGFR |
| 5.467e-04 | -7.51 | Cell Cycle, Mitotic | REACTOME pathways | R-HSA-69278 | 477 | 98 | 8202 | 1235 |
CCNE2,CEP70,SPC25,FOXM1,TUBB4B,PSME2,PTTG1,NDC80,CUL1,NUF2,PSME1,KIF2C,LPIN3,CCNB1,PRKACA,CENPN,CDKN2C,CCND1,WEE1,PCNA,PSMD1,NUP210,CCNA2,CNTRL,CEP78,PSMC2,PLK4,TUBG1,CDKN1B,CDKN2D,TUBA4A,PLK1,CENPA,CDC20,PRKAR2B,AURKB,PKMYT1,CDC25C,CDK1,GINS4,OPTN,PRIM1,PPP2R5A,RBL1,PSMD3,PPP1CB,HDAC1,SGOL1,PSMC1,CNEP1R1,PPP2R2D,PPP2R5D,PPP1R12A,CENPI,PSMD7,CDCA8,ERCC6L,PSMD10,KIF23,SPDL1,LMNA,CKAP5,TOP2A,RB1,CENPJ,TUBGCP6,NEK2,CKS1B,BUB1,KNTC1,NUP85,PSMA5,SMC4,ZWINT,PSMB4,KIF20A,CENPC,B9D2,MYBL2,POLD3,BORA,SKA1,PSMA4,LEMD2,CDCA5,E2F1,AURKA,SSNA1,CENPE,NUP37,NDE1,CEP41,NCAPG2,UBE2C,CCNB2,ESPL1,NUP58,RAD21 |
| 5.473e-04 | -7.51 | RHO GTPases Activate Formins | REACTOME pathways | R-HSA-5663220 | 114 | 31 | 8202 | 1235 |
PLK1,ZWINT,CENPA,RHOA,CENPC,SPC25,B9D2,CENPI,CDC20,NDC80,ERCC6L,CDCA8,DIAPH2,NUF2,KIF2C,AURKB,SPDL1,SKA1,CENPN,RHOB,CKAP5,PPP2R5A,BUB1,KNTC1,CENPE,NUP37,NDE1,SGOL1,NUP85,PPP2R5D,DVL2 |
| 5.507e-04 | -7.50 | GH-PRL | COSMIC cancer mutations | GH-PRL | 12 | 7 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,RET,PIK3CA,PRKAR1A |
| 5.507e-04 | -7.50 | pituitary-adenoma-GH-PRL | COSMIC cancer mutations | pituitary-adenoma-GH-PRL | 12 | 7 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,RET,PIK3CA,PRKAR1A |
| 5.533e-04 | -7.50 | AGC-kinase_C | interpro domains | IPR000961 | 55 | 18 | 18293 | 2672 |
AKT1,CIT,RPS6KA1,PRKCQ,GRK6,PKN1,PRKACA,ADRBK2,RPS6KA2,ADRBK1,STK38,PRKG1,SGK3,PRKCI,SGK1,MAST4,RPS6KA3,DMPK |
| 5.543e-04 | -7.50 | central_nervous_system-brain-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_II | 444 | 90 | 17775 | 2585 |
ARHGAP11A,NF2,GPR107,HSPG2,PPM1J,CERCAM,RET,TP53,ERBB2,PDGFRL,PLXNA1,EXT2,ART5,PICK1,PAK6,TYMP,ZNF687,ARTN,CTNNB1,CYP4F11,IQCE,PIK3CA,ZDHHC23,RTKN2,NOTCH3,NR2C1,RASGRP1,SCN3A,TRIM8,AKT1,UTRN,PRKRA,IDH1,MYOM1,PTGS2,ATP7B,SH2D3C,SPTBN5,RGS14,NXT2,FARP1,USH1C,MRC2,FRMD4A,PYROXD2,SCD5,CDCA3,ASAH1,SORBS3,JAG2,DNAH3,FAM167A,DOPEY2,RAC2,RB1,DNPEP,ADRBK1,IGSF9,FAM160A2,PTEN,ALPP,MEGF8,TUBGCP6,FDXR,ARVCF,KANK2,MAPK11,PIM1,CCDC88A,RIMS2,ACBD5,SPATA20,PCDH1,KLK5,ERMAP,MFSD2B,PIK3R1,KIAA1109,NPHP3,FNDC3A,GNA11,EGFR,GNAS,LDLRAP1,TJP3,PLA2G15,NLRC5,CSTF2,CPEB2,ESYT2 |
| 5.571e-04 | -7.49 | regulation of transcription from RNA polymerase II promoter | biological process | GO:0006357 | 1740 | 307 | 16441 | 2455 |
TXN,ACVR1,TSC22D3,HEXB,SMARCAL1,GATA3,MORF4L2,TP73,HELZ2,TGFBR3,ZFP36,FOSB,IRF2,CRY2,ZBTB18,SMARCA2,TNIP1,UXT,TFAP2C,AURKB,LDB2,ARF4,AHRR,TBX1,PRDM5,NOD2,HDAC1,NFKBIZ,RNASEL,F2RL1,E2F8,HOXC13,DDX58,KLF2,CDKN1C,ITGA6,DGKQ,SOX9,PSIP1,LMNA,MECOM,ELF3,TFAP4,CALR,CYR61,MEGF8,BHLHE41,MYDGF,MAPK7,DLX4,TRAK2,SALL4,STAT4,FHL2,MYBL2,WHSC1,ELK1,KDM3A,NFIB,NCOA3,ETS2,SEMA4D,SETD3,TCEAL4,PIAS2,NR4A2,EFNA1,PER3,RPS6KA3,TMEM173,EGLN1,IRF1,ELK4,FOXO6,TCF25,ARMCX3,GRHL2,THRA,RPS6KA1,SUZ12,WDTC1,CCND1,SP100,DACT1,DAB2IP,ETV4,NR2C1,MED30,RIPK2,FOXJ2,DRAP1,HTATIP2,PYGO1,GTF2A2,SP4,EBF2,NFIX,ZNF641,WFS1,WWTR1,STAT1,KLF5,NRG1,CBX7,ARNT,PRKAR1A,NKX3-1,CKAP2,PBX3,PKN1,ZNF219,ETS1,NFAT5,TEAD3,SIX4,WWP2,CTNNBIP1,E2F7,MCF2L,TMBIM6,ERCC2,CITED2,GFI1,MED22,NCOA2,TGIF1,CASK,PLSCR1,BCL9,TEF,PIK3R1,GRIN1,ZKSCAN2,YES1,FOS,ABLIM2,TXK,CRTC2,PITX2,FGFR2,ACVRL1,TBX18,NR4A3,GPER1,HMGA1,FZD5,OSR1,CD81,USF2,SHOX2,FOXA1,USP16,RGMA,JARID2,CCNC,EPAS1,AGRN,CRYM,SUDS3,LMCD1,TAF6L,TFAP2E,ZFYVE16,EPCAM,HSF2,PCNA,CTNNB1,GRHL1,NPNT,ZCCHC12,PSMC2,ELF5,MITF,ABCA2,DLG1,ASH2L,ARNT2,MYBL1,ZNF462,PLK1,THRB,PCGF5,KCNIP3,CXXC5,CITED4,ASXL1,NFE2L1,CBX6,EZR,EAF2,CDK1,KLF12,ZNF367,KLF11,MAFF,PSMC1,NR2C2,RUNX2,PPP1R12A,ETV5,SORBS3,BMP2,RB1,GATA2,EBF4,FNIP1,C10orf54,RFX5,WNT3A,ETV7,MDFI,ELK3,RGMB,TCF7,EGFR,FOXD2,ONECUT1,NFKBIA,NLRC5,CTBP1,RARG,RAD21,KLF7,PAX6,FOXM1,TP53,SOD2,CCNL1,OSR2,LPIN3,MXD1,PER2,TTC21B,SAP130,SS18,LMO4,SMO,BCL6,TWIST1,ZBTB49,NOTCH3,EGLN3,NFKB2,SIRT1,AKT1,TCEB2,GLO1,CD40,ARHGAP35,JADE1,HSF4,MYPOP,RBL1,STAT6,PEX2,OVOL1,TLE1,IRF7,AKNA,CBX4,CTDSP1,GLIS3,LRP4,PSMD10,HMGN3,AES,HDAC9,ZNF212,GBX2,IRF2BPL,TOP2A,BMP7,TOX2,GTF2F2,TFAP2A,BRD7,H2AFY,KANK2,HEXIM2,KLF9,WBP5,NFE2L3,HES1,RHOA,DCAF6,HMGN5,WNT10B,NR3C1,NR4A1,RGCC,PPARA,LITAF,MAML2,RUNX3,TCEAL8,FOXL1,CNOT2,TWSG1,UBE2D2,TADA2B,E2F1,ARRB1,PKD2,ZMIZ1,SOX8,AHR,PKIA |
| 5.581e-04 | -7.49 | PHOSPHOLIPID_TRANSPORTER_ACTIVITY | MSigDB lists | PHOSPHOLIPID_TRANSPORTER_ACTIVITY | 12 | 7 | 17758 | 2588 |
ATP8B1,PITPNA,CDIPT,PLSCR1,PCTP,ABCA1,ABCG1 |
| 5.581e-04 | -7.49 | MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP | MSigDB lists | MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP | 12 | 7 | 17758 | 2588 |
NUSAP1,CENPA,ANLN,UBE2C,CCNB2,ASPM,PRC1 |
| 5.597e-04 | -7.49 | condensed nuclear chromosome kinetochore | cellular component | GO:0000778 | 9 | 6 | 17570 | 2579 |
PLK1,REC8,BUB1,CENPA,CCNB1,NDC80 |
| 5.598e-04 | -7.49 | FERM_N | pfam domains | PF09379 | 29 | 12 | 16629 | 2504 |
EPB41L5,FARP1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 5.599e-04 | -7.49 | Beta-catenin independent WNT signaling | REACTOME pathways | R-HSA-3858494 | 144 | 37 | 8202 | 1235 |
TNRC6C,PSME2,PSMD7,PSMD10,CALM3,PSME1,ITPR2,GNB2,FZD6,CALM2,RAC2,PSMD1,CTNNB1,GNB5,PSMC2,PRKG1,MAP3K7,PLCB2,DVL2,PSMA5,RHOA,PSMB4,FZD4,CALM1,PRICKLE1,AGO4,SCRIB,TCF7,ROR1,ITPR3,PSMA4,FZD7,PSMD3,ITPR1,RYK,FZD5,PSMC1 |
| 5.604e-04 | -7.49 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP | 169 | 41 | 17758 | 2588 |
BIN1,SIGIRR,TNK1,ZNF395,HAPLN3,GALNT12,MORC4,NUCB2,SNX9,PHF1,LTBP3,ZNF275,ZNF212,TMEM63A,SCML1,CYHR1,SLC25A45,LYPD3,IL6ST,TMEM143,PIK3CD,CNOT6L,RCAN3,ZRANB1,CAMK2G,SUSD3,ASXL1,STMN3,IGSF8,EPHA1,BBS2,PLEKHB1,SPIN3,COQ10A,NGFRAP1,TSPAN18,EFNA1,SOX8,PPP2R2D,SNPH,FAM134B |
| 5.606e-04 | -7.49 | autonomic_ganglia-paraspinal-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-paraspinal-neuroblastoma | 26 | 11 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PIK3R1,RET,PIK3CA,SMO,ERBB2,IDH1,FLT3,EGFR |
| 5.606e-04 | -7.49 | paraspinal | COSMIC cancer mutations | paraspinal | 26 | 11 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,EGFR |
| 5.606e-04 | -7.49 | autonomic_ganglia-mediastinum-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-mediastinum-neuroblastoma | 26 | 11 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,EGFR |
| 5.606e-04 | -7.49 | autonomic_ganglia-abdomen-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-abdomen-neuroblastoma | 26 | 11 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,EGFR |
| 5.626e-04 | -7.48 | regulation of dendrite development | biological process | GO:0050773 | 105 | 29 | 16441 | 2455 |
GRN,FOXO6,RHOA,CIT,RAPGEF2,CDC20,EPHA4,GRIN1,CAMK1D,ILK,CDK5R1,PTEN,CDKL5,SEMA4D,BHLHB9,KNDC1,BMP7,PLK2,SIPA1L1,KIAA0319,NRG1,DAB2IP,EFNA1,PACSIN1,ITPKA,ARF6,COBL,LZTS1,NGEF |
| 5.631e-04 | -7.48 | human chrXq23 | chromosome location | human chrXq23 | 29 | 10 | 26250 | 2805 |
DANT2,CAPN6,BHLHB9,ALG13,CUL4B,RGAG1,ZBTB33,CXorf56,NXT2,PLS3 |
| 5.634e-04 | -7.48 | regulation of kidney development | biological process | GO:0090183 | 54 | 18 | 16441 | 2455 |
HOXB7,LGR4,SOX9,RET,GATA3,PDGFB,SIX4,PDGFA,PROM1,FAT4,CTNNB1,BMP7,WWTR1,STAT1,SMO,TACSTD2,OSR1,SOX8 |
| 5.646e-04 | -7.48 | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | MSigDB lists | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | 83 | 24 | 17758 | 2588 |
TNIP1,PLAUR,PDGFB,PHLDA1,TNFSF9,ICAM1,RHOB,CD83,SOCS3,BCL10,IER3,PDGFA,RAC2,TAPBP,PTGS2,SPP1,ETS2,NFKBIA,NAB2,PIM1,NFKB2,PTPRE,DUSP1,EHD1 |
| 5.654e-04 | -7.48 | positive regulation of immune system process | biological process | GO:0002684 | 866 | 164 | 16441 | 2455 |
LAMP1,UNC93B1,TRIM5,CUL1,GATA3,PSME1,IL18,ITPR2,CAMK1D,CACNB4,CALM2,DAPK2,PSMD1,RPS6KA2,ELMO2,IL6ST,PSMC2,PIK3CA,TNFRSF18,PIK3CD,SCARA3,SLC39A10,SMAGP,RASGRP1,CD55,TNIP1,ITCH,CR2,PLCG1,GPRC5B,LIMK1,NOD2,F2RL1,PSMC1,PPP2R5D,DDX58,LGALS3,DHPS,THEMIS2,HLA-E,PSMD7,CALM3,TEC,NCKAP1,CALR,RB1,RAC2,VASP,WDFY1,CA2,PIK3AP1,GATA2,KCNN4,PAK2,WNT3A,MAPK7,PSMA5,SOCS5,KLK5,MAPKAPK3,MICB,CALM1,ANO6,WHSC1,ELK1,CYFIP2,PSMA4,GNAS,MAPKAPK2,PVRL2,PELI2,CSF1,ITPR1,NFKBIA,NLRC5,KLK7,ARPC2,IFIH1,JAK3,RPS6KA3,TMEM173,IL15,INPP5D,RPS6KA1,PSME2,P2RX7,IL27RA,CD274,EGR3,PRKACA,TNFSF9,CD46,PLCG2,BCL6,PDE4D,TMEM64,LGMN,NFKB2,FLOT2,SIRT1,AKT1,RIPK2,LGALS8,PRKCQ,ITPR3,DUSP4,CD40,IRS2,FYN,PTPRJ,AXL,STAT6,PSMD3,IRF7,ARNT,HSP90B1,TAB3,TRAF2,CTSB,FLOT1,PSMD10,SELL,BTN3A1,PLD2,ETS1,EFNB1,ICAM1,HLA-A,ITGA2B,CTNNBIP1,IRAK1,PTEN,BAX,MAPK11,IGFBP2,RAG1,MAP3K7,CNPY3,SYK,MSH6,HES1,RHOA,ADAM17,PLSCR1,PSMB4,PIK3R1,RGCC,VAMP3,YES1,FOS,BCAR1,GPLD1,CD83,TXK,BCL10,CTSL,HLA-B,SWAP70,NR4A3,UBE2D2,PPP2R3C,ICOSLG,FZD5,CD81 |
| 5.661e-04 | -7.48 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP | 185 | 44 | 17758 | 2588 |
GALK1,CEP70,TRIM24,SERPINE2,SLC25A13,TMEM170B,DHRS3,KREMEN1,APPBP2,MAGOHB,DAZAP1,KIAA0895,PSMD1,RGS12,UBE2Q2,PFKL,TSPAN6,CST3,HSPA13,GFI1,RPGR,MSH6,WBP5,FADS2,AKT1,PBK,OXR1,ANO6,MGAT4B,MYBL2,CCBL2,PRICKLE1,FAM133B,CLCN2,GLT8D2,AMZ2,IDE,SWAP70,DHRS13,PRPS2,DTX4,MRPS28,POMT1,NCAPG2 |
| 5.661e-04 | -7.48 | YAGI_AML_FAB_MARKERS | MSigDB lists | YAGI_AML_FAB_MARKERS | 185 | 44 | 17758 | 2588 |
SERPINE2,CAST,ITGA6,CACNA2D2,MORF4L2,TRIB2,ITGA2B,FANCI,SNTA1,CAPN2,TYMP,PCNA,PDCD10,GATA2,DDHD2,FAM20B,CAPG,SORL1,TRPC1,NCAM1,RAB27B,F2R,IL10RB,MAST4,GAD1,ORAI2,PCCB,TGIF1,TIMP2,DRAP1,STAT4,ACO1,GGH,ULK2,LCP1,ALDH5A1,TIMP3,PAFAH1B3,PLOD2,HOXA9,NR4A3,NR4A2,SERPINI1,PKIA |
| 5.661e-04 | -7.48 | Rab_BD | interpro domains | IPR010911 | 12 | 7 | 18293 | 2672 |
EXPH5,SYTL4,MLPH,MYRIP,SYTL3,RIMS2,SYTL2 |
| 5.665e-04 | -7.48 | peptidyl-tyrosine modification | biological process | GO:0018212 | 155 | 39 | 16441 | 2455 |
TNK1,DYRK3,IL15,EPHA4,RET,TESK2,ERBB2,TEC,PDGFB,FLT3,DDR1,MERTK,WEE1,IGF1R,TPST1,MAP3K9,NPTN,EPHB4,F2R,SYK,RIPK2,TESK1,YES1,ROR1,EPHA1,EGFR,TXK,EPHA10,FYN,INSR,JAK1,FGFR2,AXL,PTK7,KIAA1804,RYK,MAP3K11,JAK3,MELK |
| 5.672e-04 | -7.47 | PROTEIN_KINASE_TYR | prosite domains | PS00109 | 94 | 27 | 11866 | 1802 |
TNK1,LMTK3,TESK1,EPHA4,RET,ERBB2,TESK2,TEC,ROR1,YES1,EPHA1,FLT3,DDR1,MERTK,EGFR,TXK,INSR,FYN,JAK1,IGF1R,FGFR2,AXL,PTK7,RYK,EPHB4,JAK3,SYK |
| 5.680e-04 | -7.47 | MEMBRANE | MSigDB lists | MEMBRANE | 1922 | 329 | 17758 | 2588 |
LAMP1,ACVR1,SSH1,GRIK2,SLC25A13,SYTL4,SLC20A1,SLC9A7,PICK1,GRM5,CALM2,ZYX,TGFBR3,CTGF,STIM1,SLC46A1,STEAP2,FUT1,DNM2,CLDN4,TACSTD2,IL10RB,CPE,LAMP2,SGCE,ACVR1C,SNTB2,BNIP3L,SLC17A5,SLC25A5,ENPP1,SLC25A4,GDE1,ATP7B,NOD2,TMEM8B,ARF6,SLC31A2,F2RL1,NOTCH2,MERTK,TSPAN7,DOPEY2,ITGA3,LYPD3,NECAB3,SLC16A6,CD22,OPN3,SORL1,CD70,STT3B,CACNA1D,CNGA1,FAM84B,PIKFYVE,NCAM1,NUP85,TMED2,TRAK2,NAGPA,PIGC,FADS2,QSOX1,MMD,MFI2,PTPRH,CALM1,CALCRL,EPHA1,GNA11,STX3,RHOB,PTPRF,MMP15,IL1R1,GABRD,SCARB2,SLC4A4,ITPR1,SLC4A3,MPP2,OSMR,DYSF,EFNA1,TRPC3,CBX5,NRBP1,SLC2A4,ST14,CD82,RALBP1,PKP2,IL13RA1,AIFM2,APC2,FLT3,DDR1,KTN1,CD46,MUC16,CDH1,EPHB4,TSPAN1,FZD4,COG2,CYB5R2,UTRN,HTATIP2,SLC11A2,ATP1B1,ITPR3,CBL,FZD7,FYN,STX10,DDOST,SHROOM3,SLC9A6,AXL,WFS1,HS3ST3B1,HSP90B1,MPZL1,MAN1A2,BACE1,FLOT1,CYB561,PLD2,NUCB2,KCNC4,EFNB1,ICAM1,RND1,NEO1,ITGB8,MGAT1,KCNK5,GPC3,BAX,SLC44A2,ATP8B1,TMBIM6,ERBB3,SGCB,SLC16A5,TMX1,CASK,ERMAP,PLSCR1,MPP1,VAMP3,GRIN1,SNTB1,AIF1L,GALNT3,CNTNAP1,LDLRAP1,PROM1,CTNS,ACVRL1,ABCB1,RYK,FZD5,CD81,OCLN,BCAM,TNK1,SIGIRR,EPHA4,F11R,ITPR2,CACNB4,DNER,MAP1LC3B,SDC1,SLC9A3R2,ABCD4,HTR1D,EPCAM,ENTPD4,TM9SF2,CTNNB1,IL6ST,LMAN2L,SLC44A1,DLG1,ABCA2,TRPC1,PXMP4,TRAM1,IL1RAP,LAMP3,SOD1,MCTP1,CD55,EZR,ERP44,ROR1,PLEKHB1,EDNRA,HS6ST1,KCNMB4,KCNK1,DOLPP1,MADD,POMT1,PRSS8,CD99,LGALS3,FXYD3,ABCG2,CALM3,SORBS3,B4GALT4,IL18R1,KCNN4,ICAM5,FXYD5,NPTN,SLC12A2,CKAP4,CCDC88A,KDELR1,ABCC1,PCDH1,PODXL2,RGMB,BCL2L13,STEAP1,EGFR,CDK5R1,GNAS,INSR,COL13A1,PVRL2,PLD1,ATP1B3,SHROOM2,DRD1,SORBS1,NF2,IL15,SLC2A8,HDAC11,P2RX7,MRAS,IL27RA,SLC7A2,EMP2,BCAP31,EXT2,SYTL2,ATP6V0B,SRPX,SMO,VAT1,RPN2,NOTCH3,ECE1,LMAN1,F2R,SOAT1,GCA,CLCN3,AKT1,PTPRU,PTGER4,IGSF8,ERBB2IP,CD40,DAG1,TAPBP,PTPRJ,RTN4RL1,ATP1A1,MMP17,PTK7,PEX2,SECTM1,EFNA5,AIFM3,LIFR,ABCA1,GOLIM4,TRAPPC10,TSPAN15,CD63,MCTP2,SELL,GABRG2,TGFBR1,JAG2,SBF1,LBR,FZD6,XPR1,SIRPA,SLC9A2,M6PR,IL17RB,ADORA1,MAGEE1,TSPAN13,SYK,SLC35A1,ATP2B1,GCNT1,P2RX4,SYPL1,ADAM17,IFITM3,PLAUR,AMFR,PRICKLE1,RNPEP,BCAR1,BCL10,CD83,TMEM50B,CASP7,SPINT2,PGRMC1,ARRB1,PKD2,ATP6V1C1,GOLGB1,ABCG1,CD33 |
| 5.710e-04 | -7.47 | BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | 26 | 11 | 17758 | 2588 |
S100A11,ARL4C,STAT1,RAB31,PTGER4,EMP3,EZR,HMGN3,ARHGDIB,ICAM1,SIRPA |
| 5.710e-04 | -7.47 | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN | 26 | 11 | 17758 | 2588 |
HMMR,CENPA,TXN,SPC25,ASPM,KIF14,MCOLN3,CDCA3,KIF23,CCNL1,SMC4 |
| 5.752e-04 | -7.46 | REGULATION_OF_PROGRAMMED_CELL_DEATH | MSigDB lists | REGULATION_OF_PROGRAMMED_CELL_DEATH | 340 | 72 | 17758 | 2588 |
CASP3,ACVR1,XIAP,TP53,CUL1,BCL2L1,AIFM2,BARD1,IER3,TP73,CDKN2C,DAPK2,SIVA1,BCL6,CDKN1B,TNFRSF18,F2R,CDKN2D,MX1,BAG4,SOD1,ACVR1C,CASP9,BNIP3L,HTATIP2,GLO1,STK17B,CDK1,CASP4,VCP,SOCS3,MADD,STAT1,HDAC1,HSPB1,AIFM3,CBX4,HSP90B1,DAP,CTSB,BIK,SERPINB9,NOTCH2,ADAMTSL4,GSTP1,CALR,TOP2A,CARD8,ADORA1,IGF1R,PTEN,BAX,DAPK1,CD70,PIM1,ERCC2,TMX1,GCLC,RUNX3,BCAR1,RASA1,CDK5R1,FAS,STK17A,BCL10,BTG1,SEMA4D,HTT,SCG2,MAP3K5,HIPK3,IFI6 |
| 5.754e-04 | -7.46 | RHO_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | RHO_PROTEIN_SIGNAL_TRANSDUCTION | 38 | 14 | 17758 | 2588 |
TSC1,ARAP3,RHOA,LIMK1,RALBP1,ARAP1,FGD6,TAX1BP3,ARHGDIB,ARF6,ARHGAP4,ABCA1,RHOB,FGD1 |
| 5.755e-04 | -7.46 | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | 380 | 79 | 17758 | 2588 |
GPR107,SSH1,CPT2,CAST,ACTR8,GMPR,NENF,IL13RA1,IL18,PDGFB,CYP39A1,KTN1,DAPK2,TGFBR3,FAM46A,SNX16,TAX1BP3,RNASEH2A,F2R,IL10RB,CTDSP2,SEMA3B,SSH3,MBP,S100A4,SERTAD3,SLC35C1,ERBB2IP,H2AFV,ATP10D,CYP4F3,TCN2,EDNRA,KDSR,FYN,RBL1,WWTR1,AGFG2,ABCA1,CTDSP1,KLF2,TAOK2,USH1C,RUNX2,ITGA6,EPS8,PDCL,HERC5,PLD2,WWP2,FLII,TNS3,MDM1,ADD3,FUT2,CALD1,AIM1,IL17RA,SGK1,ATP8B1,USP1,TMEM8A,DLX4,CNPY3,ARAP2,ZNF84,TACC1,YES1,SPAG1,RGS9,NCOA3,PLOD2,PRCP,CSF1,ITGA7,MATN2,ERAP1,JAK3,APOL2 |
| 5.790e-04 | -7.45 | hexose metabolic process | biological process | GO:0019318 | 181 | 44 | 16441 | 2455 |
MAN2B2,GALK1,GAA,INPPL1,ENO2,UGP2,SLC25A13,PRKAA1,WDTC1,CALM3,GALM,PRKACA,EPM2A,PER2,CALM2,FUT2,PFKL,FUT8,PIK3CA,FUT1,AKR1B1,GYS1,GOT1,BRAT1,PHKA2,PHKG2,PGM1,AKT1,PFKFB2,CALM1,PYGL,PDK3,PKM,CRTC2,MAN2A2,FUCA1,IRS2,ONECUT1,ALDH5A1,PGM2L1,MDH1,GLB1,PPP2R5D,DLAT |
| 5.826e-04 | -7.45 | FERM_PH-like_C | interpro domains | IPR018980 | 26 | 11 | 18293 | 2672 |
EPB41L5,FARP1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 5.848e-04 | -7.44 | V$NFAT_Q4_01 | MSigDB lists | V$NFAT_Q4_01 | 256 | 57 | 17758 | 2588 |
PPP4R4,PACSIN2,GPR107,HSPG2,SOX9,FLOT1,MIER3,UBE2Z,NDRG2,NKRF,HMGN3,SORBS3,MAPK4,NOTUM,ISYNA1,DHRS3,HOXB2,NFAT5,PRRG4,PPP2R3A,ICAM1,IER3,FOXP2,TFAP4,RNF220,ADRBK1,RNF128,SLC16A6,RGS3,GPC3,MITF,AKR1B1,RASGEF1A,GFI1,TIAM1,CASK,RHOA,ELK3,HN1L,FOS,ABLIM2,PITX2,TMEM54,PLOD2,NR4A3,KLF5,NR4A2,MDH1,ATP1B3,SHOX2,SEMA3A,NR3C2,PTGES,DEF6,JARID2,CTDSP1,HS6ST3 |
| 5.848e-04 | -7.44 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | 256 | 57 | 17758 | 2588 |
IER5L,ACACB,ARHGEF3,AVPI1,ARAP3,FRMD4A,ZNF395,CDKN1C,CNOT8,MCTP2,NDRG2,GPR180,RASGRP3,FAM78A,NUDT12,SLC20A1,SDC1,ARHGEF40,KREMEN1,CDS1,MUC16,SETDB2,SLC27A6,SNX18,SHC3,REEP1,ZNF692,BRAT1,TACSTD2,C10orf54,CITED2,SPRY2,DNAI1,SUSD3,SMARCA2,MBP,PRICKLE1,PDE5A,TNFAIP8L1,LRRC1,XRCC6BP1,FANCE,STEAP1,LDLRAP1,FASTKD1,DGCR2,FAM64A,RCBTB2,PAPD5,RIN3,OTUB2,RHOBTB2,ZNF165,AURKA,WDR91,NDE1,SLC25A30 |
| 5.850e-04 | -7.44 | skin-malignant_melanoma-acral_lentiginous | COSMIC cancer mutations | skin-malignant_melanoma-acral_lentiginous | 30 | 12 | 17775 | 2585 |
RB1,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,ERBB2,IDH1,FLT3,GNA11,EGFR |
| 5.850e-04 | -7.44 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_I | 30 | 12 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,SMO,PIK3CA,TP53,IDH1,GNA11,EGFR |
| 5.856e-04 | -7.44 | ZHANG_TLX_TARGETS_UP | MSigDB lists | ZHANG_TLX_TARGETS_UP | 88 | 25 | 17758 | 2588 |
HMMR,SHMT1,FIGNL1,ERCC6L,ANLN,KIF11,SKA1,CENPN,HMGXB4,FANCI,PRIM1,TOP2A,FAM111A,CCNA2,SLC4A4,RBL1,PLK4,USP1,BUB1,SGOL1,NCAPG2,TTPA,SLC12A2,NUP85,SMC4 |
| 5.856e-04 | -7.44 | MODULE_37 | MSigDB lists | MODULE_37 | 438 | 89 | 17758 | 2588 |
LMO7,ACVR1,AASS,TSC22D3,PNPLA2,TP53,GATA3,NDRG2,CCNL1,NANS,BAIAP3,BARD1,CMTM6,RNF220,TGFBR3,CYP1A1,RALB,ESPN,PDE4D,SCARA3,TUBA4A,ATG4D,GCA,TDP1,TIMP2,TCEB2,SNTB2,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRIM7,KDM4D,AMZ2,PI4K2B,ENPP1,PTGS2,NEIL1,MPRIP,SLC9A6,PLEKHG1,PPP1CB,RNASEL,PCSK5,RRAGD,LMTK3,CDH22,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,TFAP4,C9orf69,RALGPS2,CDK16,TMEM62,UBE2J1,CD9,FAR2,CITED2,EEF1D,ABCC1,MOB4,QSOX1,HMGN5,TBC1D8B,ADCK3,FMN1,MICB,FURIN,BCL2L13,FOS,EGFR,BSDC1,RHPN1,PTPRF,GALNT3,CD8A,CSF1,WDR19,S100A5,FGD6,NXPH4,TMEM120A,C17orf75,RARG,PKIA |
| 5.860e-04 | -7.44 | thyroid | COSMIC cancer mutations | thyroid | 10345 | 1580 | 17775 | 2585 |
HECA,GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,TRAPPC8,BAIAP3,ISOC2,LACTB2,DPP8,SNX9,SPSB1,CARD10,LTBP3,SLC35E4,ZNF275,GRM5,LYPD5,CDKN2C,NAPG,MUC4,ATP13A3,DNM2,CLDN4,TMEM37,TIAM1,CPE,TIPARP,ANKRD9,MGAT5,DNAAF3,CCDC74A,NEK4,FBXL16,PRKAR2B,ABR,PIAS3,ENPP1,PLCG1,CARHSP1,MPRIP,ATP7B,CELF5,TRAF3IP1,FAM114A1,NOD2,HDAC1,RNASEL,STARD13,NXT2,SCN5A,ITGA6,ARHGEF35,GPSM2,CCDC64B,FAM21C,HPCAL4,RABGGTA,ATG4A,MARCH8,FLII,SH3D21,RAC2,FRY,MEGF8,RIMS3,FLRT3,FBXL14,PCYOX1,MAP3K9,USP38,ALPK1,CNGA1,PANX2,MAPK7,ZMYM1,MOXD1,DGKG,ULBP2,KANK3,PPP6R1,TTLL1,HPS3,SHARPIN,KIF20B,ELK1,NPHP3,DPYSL4,PCTP,PSMA4,GNA11,PLIN5,C11orf45,MAGED2,IL1R1,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,OSCP1,GDF11,CBX5,TMEM173,ADAMTS16,DMPK,DOCK9,RNF224,TPRN,RHBDL3,GRK6,MOCS1,REPS1,KIAA1147,RBM23,MUC16,ST5,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,DLG3,ZNF365,MYT1,TMCC2,MX1,SNX8,COL6A2,ERMP1,C6orf1,APOBEC3D,AGPS,SEPT6,VPS4B,HTATIP2,TANC1,ZNF618,TRIM7,EBF2,GIGYF1,PDLIM3,CCNB3,SHROOM3,WFS1,AXL,PNPLA6,FAM149A,DMWD,ISOC1,MAPK12,HSP90B1,GCAT,ESRP1,TRAF2,HABP4,CCM2,SDC4,FLOT1,BTN3A1,ZNF219,SLC25A43,NFAT5,ZFX,SLC25A45,FUT2,ITGB8,IGSF9,KNDC1,CST3,TUBGCP6,KLC3,RAG1,CASD1,PARP9,ACBD5,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,UBE2A,AK4,PGBD1,RAB3IP,CNTNAP1,RPL12,RAB11FIP2,SYT7,PLA2G15,PPM1H,FBXO44,ITGAV,CMPK2,CD81,ACOT7,PHC1,TLL2,TMEM131,ILDR1,TNK1,BCAM,KIAA1462,EPAS1,ARFGEF1,PHOSPHO1,NDRG2,DNAJB11,TEX2,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,CPNE2,INPP5E,RPS6KA2,NUP210,CTNNB1,RABEP2,P4HB,IL6ST,PAPSS1,MITF,TMEM143,ABCA2,NTN4,PLK1,KRT80,THRB,PTPN18,KCNIP3,CELSR2,CBX6,CR2,CCBL2,CKAP2L,ARFRP1,EAF2,SESN1,TRUB1,DZIP1L,TNS4,PLEKHG6,PI4K2B,HS6ST1,KCNMB4,AGPAT2,HOXA9,ARRDC1,KLF11,KPNA2,TTC39C,RRAGD,RMND5A,PARP12,RUNX2,USH1C,HJURP,LGALS3,DNAJB2,RASA2,PDCL,SORBS3,ADCK5,HES2,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,RINL,FRAS1,ICAM5,FCHO1,SLC30A6,AHCY,FAR2,WNT3A,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,ZNF320,SCRIB,ZSCAN12,PDK3,BCL2L13,PRX,RASGRP2,FOXD2,FA2H,COL13A1,PHLPP2,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,AKIP1,SEMA3A,USP43,HOXB7,TP53,RHPN2,P2RX7,BAHD1,PCBP1,STIL,BCAP31,SYTL2,PDGFA,TTC21B,TACC2,BCL6,CDH3,VAT1,ESPN,NOTCH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,ERLEC1,AKT1,KIAA0040,CCSAP,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,TAPBP,ZNF628,IDE,PTPRJ,RBL1,ABHD12,STK38,MMP17,MAOA,XRCC3,IRF7,SYT13,ARHGAP4,ST3GAL1,BTBD6,CTDSP1,BIN1,ZMAT1,PINK1,CDH22,CPEB4,TAB3,KLHL13,SCD5,GNAL,MCTP2,GTF3A,GDF15,LBR,AIP,VPS26A,PARM1,IL22RA1,NRP2,DNAJB9,SH2D4A,M6PR,CD109,FOXP2,ALPP,TFAP2A,GTF2F2,FAM63A,IL17RA,SGK1,SYK,GCNT1,LRRC24,WBP5,NFE2L3,P2RX4,HES1,FBLN5,GUSB,PLAUR,CRIP2,PRICKLE1,DPP9,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,USP6,BCL10,DDX23,CNOT2,SMTNL2,NIPSNAP3A,NEIL3,ICOSLG,PTGES,ARHGEF4,GOLGB1,FAM171B,SLC35D2,LGR4,SSH1,HSPG2,TMEM86B,VANGL1,TSC22D3,PSME1,NANS,VASH1,OAT,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,CYP1A1,ANKS6,FOSB,SERINC2,POLL,KCNS3,PIK3CA,IRF2,SPATA18,CDYL,SLC35C1,KIF13A,LDB2,POR,ANKRD10,SH2D3C,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,DHPS,TBC1D1,TMEM55B,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,SH3RF2,MESDC2,C9orf69,DOPEY2,RALGPS2,LYPD3,ZNRF2,BHLHE41,VASN,AIM1,MSH2,DAPK1,TMEM51,PRKG1,ADCK2,CACNA1D,DLX4,KCTD3,SYTL3,ZNF117,GPR161,TRAK2,SOCS5,PIGC,GFPT1,SPATA20,GCC2,PRODH,KCNJ12,KLK5,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,ANTXR1,PDE11A,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,C1orf21,PIAS2,MPP2,FAM83D,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,KLK7,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,KIF3C,FOXO6,TCF25,TCTN2,CAPN12,DLGAP5,ST14,CCDC110,DDIT4L,NDRG1,CERCAM,ATP2C2,FAM78A,TMEM170B,FLT3,DDR1,ZFYVE9,EPS8L2,EPM2A,C11orf84,APOBEC3B,NOV,TRANK1,RALB,EPHB4,RNASEH2A,PDE4D,OSBPL7,FLOT2,ATG4D,DOCK4,FOXJ2,CYB5R2,DRAP1,PANK1,CLSTN1,UTRN,KIF1C,PKMYT1,PYGO1,CBL,B3GALNT2,ITPR3,ALCAM,ATP10D,FZD7,ZMPSTE24,AMZ2,DDOST,ACAD10,NGFRAP1,TSPAN18,HAGHL,TRIOBP,FAM195A,SLC27A3,PRR15,COBL,MAMDC2,PRKAR1A,HAPLN3,CENPI,NES,PLD2,DNAH3,EFNB1,HLA-A,WWP2,CKAP5,E2F7,TMEM87B,RNF128,FJX1,DRAM1,ERBB3,CITED2,TTPA,SLC16A5,MSH6,FARP2,ALDH2,ARHGEF28,B3GNT2,ZC3H11A,TMEM221,ZKSCAN2,DIAPH2,C2orf69,UBAC1,YES1,FOS,ARSK,CDK5RAP1,CRTC2,ACADSB,DGCR2,SEC14L4,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR62,FZD5,WDR91,ESPL1,CXorf56,MELK,RGMA,UGT8,CRYM,UBE2Q1,VARS2,PLAC1,ERP29,MAP1LC3B,TRIM68,HTR1D,ADPRHL1,EPCAM,SIPA1L2,HSF2,CDKL5,CASC4,ARHGEF37,METTL7A,SIVA1,CEP78,ASH2L,CTTN,MYRIP,BTBD3,STK35,SP5,LAMP3,CYP1B1,CXXC5,ASXL1,LAP3,ITCH,RGAG1,TYSND1,MAN2A2,GPRC5B,KCNK1,MADD,TDRD7,SH3GLB2,ZNF165,GLA,CHPT1,LASP1,ARAP3,ZNF395,SERPINE2,PYROXD2,ETV5,PM20D2,FAM81A,ADAMTSL4,DUSP5,QSOX2,NOXA1,PFKL,FAM20C,OCRL,COL6A1,MTMR10,LIMCH1,BRAT1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,CCDC88A,SNED1,SNX7,TPGS2,PODXL2,VWA1,PDE5A,KIAA1109,PRRC1,HEATR5A,NUBP1,PDIK1L,MFSD7,RANBP9,RHPN1,INSR,TMEM30A,SH3BP4,NXPH4,DONSON,SHROOM2,JAK3,TOB1,COL16A1,AFAP1,APOL2,LMO7,DYNLRB1,NCKAP5,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,EXT2,KCTD9,SAP130,ZNF687,ARTN,CYP4F11,KIF14,ZBTB49,ECE1,ETHE1,NFKB2,UPF3A,SOAT1,RFK,PTPRU,TMTC2,PDHX,CASP4,ARHGAP35,HSF4,ALDH5A1,STAT6,SECTM1,SPTBN5,MAD2L1BP,ABCA1,LNP1,GLIS3,FBLIM1,ENO2,ARHGEF11,TSPAN15,ARHGEF7,COL4A5,INTS8,SBF1,NTAN1,RBP7,XPR1,ITGA2B,HDAC9,SYDE2,TMEM63A,KIF5B,TOP2A,MZT2A,CARD8,TAF1B,LLGL2,A4GALT,BMP7,RRBP1,H2AFY,ARVCF,KANK2,CLIP2,RPGR,MYO5A,DCAF6,WNT10B,RC3H2,TTC7A,RUNX3,LEPR,LEMD2,ENDOD1,CD8A,CASP7,TRIM69,SPINT2,CSGALNACT1,ARRB1,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,ACACB,KLK10,TRIM24,IL15RA,TRIM5,MMADHC,CACNA2D2,SMARCAL1,DHX8,NRG2,LGI3,MORF4L2,SYTL4,BARD1,KIF26A,PHF1,EPDR1,CALM2,DAPK2,TP73,ZYX,WEE1,TGFBR3,RGS12,ARHGAP42,KIAA1107,DNAH6,CYP2S1,PPP1R16A,SLC46A1,RDH14,ALDH1A3,TUBG1,SEMA3G,PIK3CD,TINAGL1,ACOX2,ODF2L,APOBEC3G,ERAP2,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,MTRF1L,LOXL2,F12,ICMT,PPP1R14C,MYOM1,CYP4F3,COL12A1,SLC44A3,PGF,TRIM47,CAMK2N2,GRID2IP,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,SERPINB6,PDPR,GAB1,E2F8,SOX9,STRN4,ZNRF3,MERTK,LMNA,RAVER2,ELF3,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,STT3B,C9orf72,EPHX1,NAGPA,SLC37A1,SALL4,STAT4,MYBL2,PLS1,MEST,DCP2,CYB5A,DHX32,PTPRF,NAAA,NCOA3,HTT,TEX30,ITPR1,DYSF,AURKA,OSMR,DRP2,ZNF502,TRPC3,RPS6KA3,XDH,EGLN1,MTM1,CCDC109B,PAPSS2,TMSB15A,GALNT12,FAM131C,ACTR8,WDTC1,PKP2,PRSS22,APC2,KTN1,CCND1,SCNN1A,SCN3A,CAMSAP3,SSH3,PSRC1,SYNE2,CYS1,CDCA2,RAB38,IRS2,PEX5,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,TAOK2,TNRC6C,PARP14,RASSF7,PDIA3,ANO9,PKN1,NUCB2,ETS1,KCNC4,TSPAN17,SRPX2,HOXB2,ICAM1,PDIA4,NEO1,CAPN2,DTX3L,CXCL16,ANK1,ADD3,IRAK1,ANKS1B,CALD1,FDXR,ADAM15,MAPK11,ZNF230,WWP1,NPTXR,ITM2C,S100A6,CRTAP,HCN3,AMOTL2,NUDT8,LCA5,CTNNAL1,FMN1,RAPGEF2,MFSD2B,GRIN1,PLEKHA7,DBR1,MYEOV,BLVRA,FAM109A,SNTB1,CRISPLD2,ABLIM2,TXK,PITX2,KIAA0141,ATXN7L3,CCDC6,ZFP30,ARFGAP3,CENPE,CYBRD1,UNKL,SIGIRR,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,FHDC1,MCCC1,TP53I11,CDIPT,HDAC6,NUP62CL,SHC3,MKRN3,LMAN2L,TNFRSF18,ANO4,TLN2,PXMP4,MYBL1,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,ING1,CITED4,C12orf65,EZR,ERP44,ESYT1,ANLN,PRKRA,IDH1,CLCN2,LHFPL2,VCP,IRX3,DPYSL3,PLCH1,MFAP3L,CDCA4,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,PIEZO1,TTC9,GLCCI1,PRKAA2,UBASH3B,HLA-F,RACGAP1,CNTNAP2,B4GALT4,DOCK11,SSX2IP,CORO1B,BMP2,RB1,DAZAP1,VASP,IGF1R,GATA2,SPIN4,TMEM8A,PLCB2,ABCC1,C9orf9,CHSY3,CYP26B1,WDR72,CORO2A,SPATA13,KBTBD8,TCF7,EIF2AK1,UNC45B,G2E3,MAPKAPK2,COQ10A,ITGA7,PRPS2,LTBP2,CTBP1,RNF146,NIPA1,AVPI1,KCNAB3,NF2,UPF3B,FOXM1,XYLT1,ZNF28,ERBB2,LPIN3,SDF4,ATP6V0B,SRPX,EFR3A,N4BP3,PLCG2,LHX6,SRR,GYS1,MINPP1,SCN2A,DVL2,CTH,SIRT1,TMTC1,FIGNL1,CDC20,MYPOP,DUOX1,ATP1A1,PRRT4,RTN4RL1,PTK7,PSMD3,ADAMTS14,ANXA9,AIFM3,NDST3,ZC3HC1,MAN2B2,GSDMD,COL9A3,PACSIN2,GOLIM4,TRAPPC10,MACC1,PSMD10,NKRF,JAG2,DSE,SLC9A2,SIRPA,GBX2,MAGEE1,ABCD1,SLC45A3,IGDCC4,DLGAP1,PSMB4,AMFR,PPARA,CAPNS1,AKAP3,FXR2,FNDC3A,BCAR1,MAPK8IP1,FUCA1,TMEM50B,BANK1,FAT4,SERPINA1,NMI,NETO2,PKD2,UBE2C,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,TTC39B,ATP8A1,FAM129B,KLC2,PPFIBP2,TAP1,GATA3,PLXNA1,CCNB1,FAM101B,CHST2,SESN3,ZFP36,RGS3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,TFG,XKR8,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,GALNT7,MCFD2,SLC25A5,ZFAND5,SPNS3,ARHGEF26,SGPP1,AHRR,KDSR,SLC25A4,RBM47,AREG,PLK2,TBX1,GNPTAB,NKD1,FAM110C,DHTKD1,TMEM8B,UNC5B,RTN3,LZTS1,DLAT,DDX58,KLF2,INPPL1,FRMD4A,HLA-E,ADO,DGKQ,KIF23,C6orf106,NOTCH2,BMP2K,KIAA1161,MECOM,ITGA3,PIK3AP1,SNX18,SLC16A6,BDH1,RUNDC3B,SORL1,TNFRSF12A,CD70,PIKFYVE,TSPAN33,EEF1D,RIMS2,IGSF3,EPB41L5,QSOX1,MFI2,MMD,TBC1D8B,AMER1,PTPRH,ANO6,PIP4K2C,VEZT,PKM,KDM3A,FBXO10,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,TMEM54,DCK,NAB2,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,PKD1L2,IRF1,FRMPD3,PLEKHG3,CEP70,ARMCX3,TRIP10,NLRX1,BROX,IQGAP1,RPS6KA1,IRX4,NUDT12,AIFM2,MNS1,TMPRSS4,CYHR1,ZNF75D,FAM46A,CDKN1B,CNNM4,PHKA2,LGMN,NR2C1,TMBIM1,GPX4,TBC1D10B,MYO5B,SEC23A,CAPN6,TMEM43,TEP1,PRKCQ,SLC11A2,C15orf39,AKR1E2,SP4,ZNF469,PRDM11,NIN,EPHA10,FYN,JAK1,KIAA1804,STAT1,NRG1,HS3ST3B1,B4GALT3,NR3C2,ATMIN,DENND5B,OTUD5,MRPS9,WASF3,ANKRD13D,PCOLCE,SLC16A14,JRKL,CDCA3,CYB561,APOBEC3H,SEPP1,SPR,PNPLA5,TEAD3,SIX4,LGALS3BP,TMCC3,SNTA1,FAM111A,PHF7,PTEN,CENPJ,PRC1,CNPY3,GFI1,TRIM62,SPRY2,NCOA2,OSGIN1,RASGRF1,SHMT1,ARAP2,FURIN,VAMP3,PARP4,LRRC1,GPLD1,NUCB1,MAMDC4,CTNS,RCBTB2,SERPINB5,PGM2L1,GRIN2D,ETAA1,ARSB,NCAPG2,OCLN,USP16,JARID2,ESYT2,EXPH5,EMX1,LTBP1,NMRK1,CASP3,HEBP1,EPHX4,TAF6L,KIF2C,KREMEN1,TMC1,DENND2D,TSEN34,PTCHD4,SH3KBP1,CHPF,ABCD4,ARHGEF10L,ZCCHC12,IMPAD1,DLG1,POF1B,ANKRD12,SUN3,RAB20,RP2,MYH14,TECR,PTPRE,RASGRP1,TDP1,ATL1,TRIM8,SYNE3,ASCL5,RNF165,ROR1,PTGFRN,STK17B,TCN2,SEC14L2,MDK,CXXC4,LRRC42,ARHGEF19,FASTKD1,DHRS13,IARS2,CCDC74B,ADIPOR1,LEMD1,RAP1GAP,PPP2R5D,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,LYSMD4,OTUD1,ZNF432,AIM1L,LRRN2,KCNN4,EBF4,FNIP1,FXYD5,ZNF692,KNTC1,RFX5,NCEH1,ALS2CL,KDELR1,PARD3B,OXR1,GYLTL1B,BTN3A2,AMDHD1,EGFR,GLCE,GNAS,FECH,BCAR3,SLC6A6,CGREF1,NFKBIA,ALPK3,RHOBTB2,PITPNA,KIF12,PROM2,FBXW5,GAS2L1,SLC25A24,ZSWIM5,SPC25,ABCG4,GMPR,ZMYND10,MICALL2,SS18,SETDB2,KHNYN,ZDHHC12,FRYL,SMO,RPN2,TWIST1,APIP,F2R,LOXL1,PDIA6,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,ZNF525,BAG4,TAF5,KREMEN2,IGSF8,ERBB2IP,DOCK5,KCTD2,BHLHB9,PEX2,CANT1,VSIG10,PLXND1,CYP2U1,AKNA,REEP4,LIFR,CBX4,CCDC24,ANXA3,CDS2,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,AES,POMGNT1,FAM167A,ZNF212,SAC3D1,IL17RB,IRF2BPL,MDM1,ADORA1,MLPH,GALNS,KIAA0319,TRIM3,IQGAP3,SUN2,NR4A1,PHLDB3,ASPM,OGDHL,MBNL3,LRRC66,SPAG1,MPV17L2,MAP1B,KLHL2,HLA-B,C2orf70,HNRNPH2,DHRS2,GLB1,HOXB13,SOX8,ATP6V1C1,L1CAM,SNPH |
| 5.862e-04 | -7.44 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN | 196 | 46 | 17758 | 2588 |
GALK1,LGALS3,CKAP2,KIF23,RACGAP1,FBXO6,PRKACA,IFT27,MNS1,IL18R1,PDIA4,CKAP5,TOP2A,SIVA1,CAPG,PLK4,CKS1B,TUBG1,BUB1,AK3,IL10RB,CRTAP,S100A6,CENPA,SH3BGRL,CDC20,RC3H2,HTATIP2,TNFAIP8L1,NUSAP1,ANLN,MEST,MRPS36,CDK1,C4orf27,CDKN2AIPNL,PAFAH1B3,RBL1,CCDC6,DCK,AURKA,CMPK2,F2RL1,CCNB2,ACOT7,XDH |
| 5.862e-04 | -7.44 | GSE360_DC_VS_MAC_L_DONOVANI_DN | MSigDB lists | GSE360_DC_VS_MAC_L_DONOVANI_DN | 196 | 46 | 17758 | 2588 |
HSP90B1,ENO2,PPP1R12A,TSC22D3,RPS6KA1,ARHGEF7,CTDSPL,SEPP1,DHRS3,BCAP31,PDIA4,RPS6KA2,TIMP1,CD9,TMBIM6,MDFIC,IFIT1,MANF,CTDSP2,ALDH3A2,PPIF,PGM1,CD55,ZWINT,ZC3H11A,GUSB,GCLC,SH3BGRL,MPP1,MRS2,KDM3A,RASA1,FRMD4B,FYN,ALDH5A1,RCBTB2,RND3,STK38,TRAF3IP1,DTX4,PPM1H,PLXND1,GEM,RPL22,USF2,RPS6KA3 |
| 5.862e-04 | -7.44 | GSE17721_POLYIC_VS_CPG_0.5H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_0.5H_BMDM_DN | 196 | 46 | 17758 | 2588 |
SUN1,PLA2G4A,TBC1D1,HLA-E,RAB23,ASAH1,PRSS22,TGFBR1,MPP5,INTS8,DHRS3,EFNB1,HMGXB4,MDM1,RNF128,ICAM5,FAM20B,PRKCI,EPHB4,C10orf54,SLC35A1,EBAG9,CERS2,GCNT1,MOB4,PCCB,KCNJ12,NRBF2,LAP3,FOPNL,LYRM1,C1GALT1C1,NUSAP1,ERBB2IP,MCFD2,B3GALNT2,BCL2L13,CDC25C,C4orf27,DGKE,ALDH3B1,C19orf66,DCK,PGRMC1,ATP6V1C1,RPS6KA3 |
| 5.863e-04 | -7.44 | cytoplasmic vesicle membrane | cellular component | GO:0030659 | 435 | 89 | 17570 | 2579 |
SUN1,LAMP1,IL15RA,SLC2A8,ATP8A1,SYTL4,SAYSD1,SNX9,PHLDA1,APPBP2,SH3KBP1,PICK1,CD46,ATP6V0B,AP1M2,N4BP3,SMO,DNM2,RAB20,PACSIN1,LMAN1,RAB27B,FLOT2,CPE,MYRIP,SMAGP,LAMP3,MYO5B,LAMP2,SEC23A,CLCN3,FZD4,SNTB2,RAB38,MCFD2,ULK2,GABARAPL1,GPRC5B,AREG,RAB11FIP1,NRGN,COPG1,ARFGEF3,ANXA3,TAOK2,PACSIN2,CD63,HLA-E,BACE1,HLA-F,RAB23,ITGA2B,HLA-A,FZD6,MARCH8,RAC2,SNX18,ZNRF2,OCRL,ZDHHC13,CD9,CADPS2,HLA-C,WNT3A,GAD1,GPR161,CAMK2G,TMED2,KDELR1,SNX7,SYPL1,RAB3B,VAMP3,ATP8B3,C3orf58,EGFR,HLA-B,LDLRAP1,HTT,RAB11FIP2,TMEM30A,ITPR1,RAB31,DYSF,ARRB1,GPER1,FZD5,TBC1D4,TMEM173 |
| 5.872e-04 | -7.44 | tube formation | biological process | GO:0035148 | 140 | 36 | 16441 | 2455 |
CTHRC1,GRHL2,ST14,SOX9,SDC4,RET,RAB23,GATA3,NCKAP1,PRKACA,STIL,FZD6,VASP,CTNNB1,LMO4,TWIST1,DAB2IP,MAP3K7,DVL2,TGIF1,SALL4,PRICKLE1,KIF20B,SCRIB,NFIB,BCL10,ARHGAP35,IRX3,TSC1,SHROOM3,PTK7,SPINT2,SOX8,OSR1,COBL,RARG |
| 5.878e-04 | -7.44 | cellular response to stress | biological process | GO:0033554 | 1642 | 291 | 16441 | 2455 |
ADD1,DNAJC3,XIAP,FBXO2,SMARCAL1,CCNO,CUL1,PSME1,MORF4L2,CCNB1,BARD1,PHF1,PICK1,TP73,PAK6,PHYHIP,PSMD1,UBE2T,POLL,PIK3CA,DNM2,CRY2,PPP1CA,NEK4,SPATA18,CASP9,SPRTN,KDELR3,SLC35C1,PIF1,MYOM1,GINS4,SH2D3C,MYLK,NOD2,MAP3K11,SERPINB6,GAB1,RECQL,KLF2,NUAK1,SEC61G,PRKAA1,SLC1A3,TNFRSF19,LMNA,ATG4A,TFAP4,CALR,ZCCHC17,RIMS3,VASN,FAM13B,MSH2,MAP3K9,PRKG1,USP1,ALPK1,STT3B,MYDGF,MAPK7,NUP85,GFPT1,REC8,DDB2,UFD1L,PRODH,MAPKAPK3,ERO1A,WHSC1,ELK1,PSMA4,RHOB,FAS,PTPRF,MATN2,ITPR1,MDH1,NR4A2,STK39,MAP3K5,NUP58,RPS6KA3,EGLN1,SLC2A4,NQO1,RPS6KA1,ACTR8,NDRG1,PTTG1,BCL2L1,CCND1,CCNA2,SP100,RALB,CDKN1B,DAB2IP,RNASEH2A,CDKN2D,RNF169,ATG4D,CDKN2AIP,SEC61B,RIPK2,NRBF2,SLC11A2,ATP1B1,RAD17,XRCC6BP1,AKR1E2,ALDH3B1,STK26,WFS1,KIAA1804,RGS14,GEN1,ARNT,ATMIN,MAPK12,MRPS9,HSP90B1,TAOK2,NKX3-1,TRAF2,CCM2,FLOT1,PDIA3,FBXO6,PKN1,ETS1,TIPRL,ICAM1,PDIA4,DTX3L,E2F7,PDCD10,IRAK1,PTEN,CST3,BAX,TMBIM6,MAPK11,ERCC2,CITED2,MAP3K7,TMX1,MSH6,PARP9,PAPD7,PIK3R1,UBE2A,PARP4,FOS,PLOD2,PRDX3,SLC35B3,OSER1,HMGA1,NUP37,WDR45B,CPEB2,MELK,USP16,CASP3,FAF2,EPAS1,CUL4B,LMCD1,DNAJB11,HDAC6,MAP1LC3B,FANCI,NUP210,RPS6KA2,PCNA,P4HB,PSMC2,AKR1B1,DUSP10,ASH2L,KIF22,CYP1B1,PLK1,TDP1,SOD1,NFE2L1,ERP44,PRKRA,SESN1,CDK1,VCP,KDM4D,NEIL1,WIPI1,CAB39,KPNA2,PPP2R5D,PSMC1,NR2C2,RRAGD,PRKAA2,DNAJB2,ETV5,PSMD7,ANO1,SPP1,CA2,PAK2,FNIP1,BRAT1,MDFIC,SELK,PSMA5,HP1BP3,MDFI,OXR1,STRADB,EIF2AK1,PDK3,MAPKAPK2,NFKBIA,CDCA5,YOD1,RAD21,USP43,DRD1,GAS2L1,SLC25A24,FOXM1,PSME2,TMX4,XYLT1,SOD2,TP53,PDIA5,RAD23A,IER3,SRPX,BCL6,TWIST1,EGLN3,SCN2A,PDIA6,CTDSP2,CTH,PPIF,SIRT1,BAG4,ERLEC1,AKT1,TCEB2,PTGER4,MRPS35,DUSP4,FANCE,MAP3K6,CASP4,PTGS2,DNAJC10,RTN4RL1,PSMD3,IRF7,XRCC3,PINK1,CPEB4,TAB3,JKAMP,SHPRH,DAP,SWI5,PSMD10,DNAJB9,TOP2A,BMP7,UBE2J1,SGK1,SYK,CAMK2G,RHOA,PSMB4,AMFR,RGCC,TXNDC11,POLD3,MAPK8IP1,NEIL3,DHRS2,CTSV,UBE2D2,E2F1,PKD2 |
| 5.893e-04 | -7.44 | REGULATION_OF_CELL_CYCLE | MSigDB lists | REGULATION_OF_CELL_CYCLE | 180 | 43 | 17758 | 2588 |
CCNE2,CDKN1C,TP53,HERC5,CUL1,NOTCH2,BMP2,CCND1,NPM2,CDKN2C,DIRAS3,RB1,BTG3,CCNA2,PTEN,BMP7,DLG1,NEK2,CKS1B,CDKN1B,BUB1,KNTC1,ERCC2,HEXIM2,CITED2,CDKN2D,CKS2,ZWINT,RUNX3,NUSAP1,RAD17,PKMYT1,ANLN,SESN1,CDC25C,CDK5R1,RHOB,CDK5RAP1,DHRS2,MADD,TMEM8B,UBE2C,MAPK12 |
| 5.897e-04 | -7.44 | vpu (p16) | protein interactions | 155945 | 241 | 58 | 16036 | 2547 |
LAMP1,CASP3,CD63,TRIM5,HLA-E,CD82,HLA-F,TMEM55B,TP53,ARFGEF1,FLOT1,SELL,CUL1,TGFBR1,TGOLN2,BCL2L1,TSPAN7,NFAT5,HLA-A,ICAM1,SGPL1,CD109,TGFBR3,CTNNB1,CDH1,ATP5H,RANBP1,FOSB,DNM2,BAX,IGFBP2,IFIT1,HLA-C,APOBEC3G,ATP2B1,CERS2,CHP1,PLK1,LAMP2,MX1,UFD1L,VPS4B,SRSF5,IFIT3,CD40,FOS,SMN1,VCP,CD83,FAS,CNTNAP1,HLA-B,SEMA4D,NFKBIA,STAT1,AURKA,CD81,RTN3 |
| 5.907e-04 | -7.43 | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | 60 | 19 | 17775 | 2585 |
NF2,AKT1,RET,PIK3R1,TP53,ERBB2,FLT3,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,MSH2,JAK3,MSH6 |
| 5.907e-04 | -7.43 | papillary | COSMIC cancer mutations | papillary | 60 | 19 | 17775 | 2585 |
ADAMTS2,TAOK2,NF2,AKT1,DNAJC3,DUSP23,CCM2,UTRN,EPHX4,KIF1C,PDK3,RSAD1,EGFR,CTNNB1,PTEN,HTT,PELI2,PIK3CA,ARF6 |
| 5.912e-04 | -7.43 | Insulin resistance | KEGG pathways | hsa04931 | 111 | 31 | 6908 | 1076 |
PRKAA2,GFPT1,ACACB,SLC2A4,AKT1,RPS6KA1,PRKAA1,PIK3R1,PPARA,PYGL,PRKCQ,SOCS3,IRS2,CRTC2,PTPRF,PRKAG2,RPS6KA2,INSR,SLC27A6,PTEN,NFKBIA,PPP2R4,PIK3CA,PPP1CB,GYS1,SLC27A1,PPP1CA,PIK3CD,TBC1D4,SLC27A3,RPS6KA3 |
| 5.921e-04 | -7.43 | stem cell development | biological process | GO:0048864 | 125 | 33 | 16441 | 2455 |
SEMA6B,ACVR1,RET,SOX9,TGFBR1,FAM101B,EFNB1,FGF19,GBX2,BMP2,TGFBR3,CTNNB1,BMP7,SMO,ADAM15,TWIST1,SEMA3G,SEMA3B,EPB41L5,HES1,S100A4,LOXL2,EDNRA,PITX2,SEMA4D,FGFR2,CORO1C,TBX1,FAM83D,NRG1,EFNA1,SOX8,SEMA3A |
| 5.933e-04 | -7.43 | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D | MSigDB lists | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D | 329 | 70 | 17758 | 2588 |
UNKL,SLC2A4,GRHL2,EPAS1,RPS6KA1,PLXNA1,BAHD1,SDC1,FAM46C,CCND1,WEE1,LHX6,BCL6,IRF2,NTN4,TIPARP,FOXJ2,GIGYF1,MFAP3L,HLF,KLF12,CDK19,RBL1,RAB11FIP1,MAP3K11,AGFG2,KPNA2,ZBTB6,ABCA1,RRAGD,NR2C2,TAOK2,FRMD4A,JRKL,MIER3,PBX3,RAB6A,SSX2IP,NEO1,MARCH8,TFAP4,E2F7,UBE2Q2,ITGB8,GNB5,LYPD6,UBE2J1,FAM134C,DPYSL5,CYP26B1,DCAF6,TBC1D8B,OXR1,ANO6,KBTBD8,FNDC3A,TP53INP2,NFIB,CRTC2,BTG1,PHLPP2,NR4A3,DCUN1D1,CLIP4,FAM117A,YOD1,NR4A2,RPS6KA3,RGMA,DRD1 |
| 5.954e-04 | -7.43 | PID_HIF2PATHWAY | MSigDB lists | PID_HIF2PATHWAY | 34 | 13 | 17758 | 2588 |
SIRT1,TCEB2,EPAS1,ABCG2,TWIST1,SLC11A2,EFNA1,ELK1,CITED2,EGLN3,ETS1,ARNT,EGLN1 |
| 5.954e-04 | -7.43 | SCHRAETS_MLL_TARGETS_UP | MSigDB lists | SCHRAETS_MLL_TARGETS_UP | 34 | 13 | 17758 | 2588 |
BTG3,SERPINE2,CTSC,ACTA2,NES,CTSZ,FHL1,FOS,TSPAN7,TOB1,GM2A,FZD6,FAS |
| 5.962e-04 | -7.42 | endocytosis | biological process | GO:0006897 | 491 | 100 | 16441 | 2455 |
ILDR1,GPR107,TRIP10,RALBP1,P2RX7,FTH1,ITPR2,BCL2L1,SNX9,DNER,TMPRSS4,ZFYVE9,SH3KBP1,SUSD2,RABEP2,SRPX,ELMO2,DPYSL2,PLCG2,STEAP2,PIK3CA,DNM2,RAB20,TINAGL1,CTTN,MARCH2,SCARA3,PACSIN1,SNX10,XKR8,SNX8,CLCN3,EZR,SYP,LOXL2,ITPR3,SNX12,ADRBK2,ENPP1,PLCG1,FYN,DNM1L,CORO1C,LIMK1,AXL,ABCA1,ANXA11,GRN,BIN1,ANXA3,HSP90B1,MRC2,INPPL1,PACSIN2,SORT1,ATP9A,LRP4,PLD2,NCKAP1,MERTK,LGALS3BP,M6PR,CALR,CXCL16,ADORA1,ADRBK1,SNX18,RINL,GATA2,ICAM5,FCHO1,CD9,SORL1,PIKFYVE,SYK,C9orf72,SNX7,MAPKAPK3,PIK3R1,PGBD1,CALCRL,SCRIB,EIF2AK1,YES1,NEURL1B,CYFIP2,MAPKAPK2,LDLRAP1,CSNK1G1,RIN3,ITPR1,SH3BP4,RAB31,ARRB1,ITGAV,ARPC2,CD81,SNX30,ESYT2,EHD1 |
| 5.966e-04 | -7.42 | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 30 | 12 | 17758 | 2588 |
PITX2,CD55,CTGF,MICB,HLA-E,TFAP2A,CCNO,EMP3,MDFIC,HLA-C,SEPP1,CTH |
| 5.966e-04 | -7.42 | SIMBULAN_PARP1_TARGETS_UP | MSigDB lists | SIMBULAN_PARP1_TARGETS_UP | 30 | 12 | 17758 | 2588 |
CCND1,ANXA3,NOV,TIMP2,TIMP3,SERPINE2,IGFBP6,COL4A5,CTTN,TINAGL1,CD81,S100A6 |
| 5.966e-04 | -7.42 | RODRIGUES_NTN1_AND_DCC_TARGETS | MSigDB lists | RODRIGUES_NTN1_AND_DCC_TARGETS | 30 | 12 | 17758 | 2588 |
ARHGEF3,MMD,CDKN1C,ETS2,KIF13B,PPARA,H2AFY,NFKBIZ,KLF9,TBC1D4,FOS,ELF3 |
| 5.987e-04 | -7.42 | lung-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-squamous_cell_carcinoma | 15429 | 2295 | 17775 | 2585 |
HECA,FAM160B1,PNPLA2,MCOLN3,CCNO,TGOLN2,DPP8,FAM46C,SPSB1,SLC35E4,GRM5,PHYHIP,UBE2T,PAQR5,ATP13A3,DNM2,PPP1CA,CPE,DNAAF3,CCDC74A,NEK4,FBXL16,TFAP2C,PNKD,ABR,LCP1,PIAS3,MPRIP,C17orf51,NOD2,TMOD2,STARD13,ANXA11,ZNF720,SEC61G,GGA1,ITGA6,MTL5,RAB23,ARHGEF35,GPSM2,FAM21C,TTYH3,ATG4A,SH3D21,RAC2,FRY,FBXL14,MAP3K9,USP1,PANX2,CNGA1,MAPK7,MOXD1,NUP85,PPP6R1,TTLL1,MCCC2,FHL2,ELK1,NPHP3,DPYSL4,PCTP,PLIN5,MAGED2,CACHD1,SLC4A4,ETS2,RAET1L,DGAT2,OSCP1,TMEM173,DMPK,WDR63,C5orf30,MGST2,KIAA1147,RBM23,MUC16,ENPP5,ZNF365,MYT1,SNX8,ERMP1,RIPK2,APOBEC3D,AGPS,PTPN9,SEPT6,VPS4B,HTATIP2,SYP,DNAJB14,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,NFIX,PDLIM3,SHROOM3,CDK19,CORO1C,WFS1,AXL,FAM149A,PRIMA1,SLC25A30,CTHRC1,HSP90B1,MPZL1,CKAP2,ESRP1,BACE1,HABP4,CCM2,SDC4,FLOT1,BTN3A1,CTSZ,ZNF219,NFAT5,DIRAS3,IGSF9,GPC3,MGAT4A,TUBGCP6,BAX,FAM102A,IGFBP2,CASD1,ACBD5,PVRL4,TACC1,PIK3R1,NUB1,MRS2,PGBD1,RAB3IP,CNTNAP1,RAB11FIP2,SYT7,SLC35B3,FAM3C,PLA2G15,FBXO44,ACOT7,SRSF9,TLL2,BCAM,TNK1,KIAA1462,EPAS1,CNOT8,ARFGEF1,F11R,NENF,MGAT5B,PLS3,BTG3,INPP5E,ENTPD4,RPS6KA2,NUP210,RABEP2,P4HB,TMEM143,ABCA2,NTN4,PTPN18,MARK1,STAU2,CBX6,NFE2L1,CR2,ARFRP1,TRUB1,DZIP1L,TRIM9,PI4K2B,TMEM164,TRAM2,KCNMB4,HOXA9,ARRDC1,KLF11,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,NCKAP1,RSAD1,TNS3,RINL,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,AHCY,PIM1,FAR2,NTN1,DPYSL5,PCDH1,USP31,STRADB,ZSCAN12,PDK3,CDK5R1,PRX,COL13A1,KBTBD2,PHLPP2,OTUD6B,NLRC5,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TMX4,RHPN2,BCAP31,TACC2,LMO4,BCL6,PLK4,ZDHHC23,CDH3,GLB1L2,OAS3,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,C3orf33,ATP13A2,IDE,PTPRJ,CHMP4B,IRF7,SYT13,ZMAT1,PINK1,CDH22,KLHL13,TAB3,GNAL,MCTP2,CDCA8,GTF3A,DNAJB9,ZDHHC21,FOXP2,LYPD6,UBE2J1,IL17RA,ALDH7A1,FAM134C,ATP2B1,GCNT1,DUSP1,NFE2L3,FBLN5,RHOA,DPP9,GGH,COL7A1,DDX23,SCG2,NIPSNAP3A,NEIL3,PTGES,HIPK3,ZBTB33,SLC35D2,TXN,PNISR,LGR4,SSH1,HSPG2,C1orf198,CAMK1D,VASH1,PJA2,PICK1,SLC9A7,ASPHD2,PAK6,ANKS6,OSBPL3,FOSB,SERINC2,KCNS3,IRF2,SNX16,SGCE,SPATA18,BNIP3L,SLC35C1,KIF13A,ANKRD10,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,SPRY4,F2RL1,SLC31A2,CCDC97,FGD1,RECQL,TBC1D1,TXNDC9,PSIP1,SH3RF2,DOPEY2,LYPD3,AIM1,MSH2,TMEM51,PRKG1,ADCK2,C8orf58,CACNA1D,SYTL3,GPR161,TRAK2,GFPT1,GCC2,PRODH,KLK5,PRSS23,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,APPL2,AGBL5,SFMBT1,SAMD8,CDK18,KLK7,ZBTB34,PER3,EHD1,TCF25,DDIT4L,ATP2C2,FAM78A,TMEM19,CYP39A1,EPM2A,NOV,CCNA2,ACAP2,TRANK1,BRI3,PDE4D,OSBPL7,MED30,NAGA,ATG4D,DOCK4,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ASB13,FZD7,POPDC3,ACAD10,NGFRAP1,TRIOBP,ZNF704,CBX7,MAMDC2,DEPDC1,IGFBP6,HAPLN3,EPS8,HERC5,PLD2,EFNB1,FGF19,WWP2,SLC25A36,RASSF8,E2F7,TMEM87B,RNF128,CCDC82,CITED2,TTPA,SLC16A5,FARP2,PDGFC,ARHGEF28,ALDH2,ZC3H11A,ZKSCAN2,DIAPH2,C2orf69,UBAC1,ARSK,KIF11,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,RIN3,ERAP1,WDR62,ESPL1,CXorf56,DEF6,RGMA,FAF2,CRYM,UBE2Q1,VARS2,MPP5,TRIM68,ZFYVE16,EPCAM,HSF2,CDKL5,CASC4,METTL7A,ARHGEF37,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,CYP1B1,CXXC5,CENPA,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,HPSE,KCNK1,ZNF165,SP6,PCSK5,LASP1,ARAP3,PPP1R2,ZNF395,SERPINE2,BVES,ETV5,ABCG2,ADAMTSL4,DUSP5,NOXA1,CES2,PFKL,OCRL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,ETV7,GAD1,SNED1,SNX7,SPA17,PDE5A,KIAA1109,PRRC1,NUBP1,C3orf58,RANBP9,STEAP1,SOX13,UAP1,SPAG7,DCUN1D1,RAB31,NXPH4,CTSA,TMEM14A,AFAP1,RARG,SNX30,LZTFL1,NCKAP5,DYNLRB1,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,ZNF687,KIF14,FABP6,ZBTB49,DIXDC1,EPB41L4B,NFKB2,SOAT1,RFK,MRPS35,CDC25C,FANCE,PDHX,CASP4,ARHGAP35,SOCS3,TLE1,SPTBN5,ABCA1,GCLM,FBLIM1,ARHGEF7,TGFBR1,SBF1,XPR1,TMEM63A,KIF5B,BMP7,MYCL,TOX2,RRBP1,ARVCF,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,LEPR,LEMD2,ENDOD1,ARHGAP24,CASP7,TRIM69,RAP2C,SPINT2,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,NGEF,ACACB,TRIM5,SMARCAL1,CACNA2D2,FAM102B,NRG2,LYNX1,MORF4L2,SYTL4,CNTROB,BARD1,PHF1,DAPK2,ZYX,TGFBR3,KIAA1107,CYP2S1,SLC46A1,RDH14,KLF3,FUT1,SEMA3G,TUBA4A,NWD1,SPEF2,TNIP1,SERTAD4,RNF11,MTRF1L,F12,MYOM1,CYP4F3,COL12A1,TRIM47,WDR11,GRID2IP,DNM1L,ANKRD6,MYLK,AGFG2,LSM14B,PDPR,ALDH6A1,FAM169A,TMTC3,SOX9,SLC36A4,LMNA,DNPEP,NEK2,STT3B,NDUFA12,C9orf72,KIF20A,SALL4,STAT4,MYBL2,DCP2,CYB5A,STK17A,DHX32,NCOA3,NAAA,MTFMT,HTT,SEMA4D,SETD3,TEX30,ITPR1,AURKA,ALG2,FBXO27,NDE1,DRP2,ZNF502,TRPC3,EGLN1,ACTR8,RGS20,ETNK1,IL13RA1,NUF2,PRSS22,KTN1,CDS1,CCND1,RNF220,SCNN1A,RTKN2,ACSL4,RAB27B,TMEM9,SCN3A,RNF169,ENPP4,FZD4,NRBF2,PLEKHO1,CYS1,CDCA2,RAB38,PEX5,STX10,SLC9A6,WWTR1,PDXK,ARNT,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,RASSF7,GMCL1,ANO9,ETS1,TSPAN17,SRPX2,ICAM1,CAPN2,DTX3L,ADD3,SLC27A6,FAM160A2,ARSG,KCNK5,ALG13,PLEKHF1,TMBIM6,ZNF230,AK3,ITM2C,TPCN1,HCN3,POU6F1,LCA5,NUDT8,RAPGEF2,MFSD2B,ELOVL3,EIF5A2,PLEKHA7,DBR1,EMP3,BLVRA,SNTB1,SKA1,TXK,PITX2,DCAF10,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,FHL1,SHOX2,CYBRD1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,EPHA4,HDAC6,NUP62CL,PDGFB,SHC3,MKRN3,RGS5,ANO4,TRAM1,NEB,DDX59,CCDC38,PCGF5,MCTP1,ERP44,ESYT1,ANLN,CLCN2,LHFPL2,RHEB,VCP,DPYSL3,IRX3,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,POMT1,MAFF,PRKAA2,UBASH3B,ZCCHC24,DOCK11,PGAP1,BMP2,KIAA0895,GATA2,SPIN4,EXOC8,MDFIC,PLCB2,C9orf9,TESK1,PCBP3,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,G2E3,MOSPD3,EPN3,DHDH,CSF1,ATP1B3,CTBP1,FAM45A,NF2,UGP2,DGKA,CCDC68,ERBB2,RASGRP3,KBTBD11,C1orf116,CYP26A1,RAD23A,CDK14,GYS1,EGLN3,FAR1,SIRT1,TMTC1,CDC20,DUOX1,ATP1A1,PRRT4,PSMD3,C1orf43,AIFM3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,GOLIM4,TRAPPC10,CD63,RUSC2,DAP,GNE,PSMD10,NKRF,CHAC2,SLC9A2,PPP2R3A,SIRPA,CEP97,BUB1,HEXIM2,SLC45A3,CAMK2G,IGDCC4,MLEC,NR3C1,AMFR,LITAF,PELI3,AKAP3,FXR2,FNDC3A,BCAR1,FUCA1,TMEM50B,BANK1,ZNF214,TMC5,NETO2,PGRMC1,FAM117A,PPP2R3C,TBC1D4,UBE2C,DIS3L,PPP4R4,ACVR1,TMEM41B,ATP8A1,KLC2,PLXNA1,CCNB1,SLC20A1,SESN3,CTGF,ZFP36,IL31RA,AOX1,STEAP2,TFG,RCAN3,SMYD5,XKR8,LAMP2,LOC81691,TMEM68,PBK,CASP9,HSPA12A,TNS1,GALNT7,SLC17A5,CCNF,SPNS3,ARHGEF26,SFXN1,KDSR,RBM47,PLK2,PTER,TBX1,NKD1,DHTKD1,TANC2,TRAF5,LZTS1,DLAT,KLF2,MRPL44,CDK17,ADO,DGKQ,CALB2,KIF23,C6orf106,SLC1A3,NOTCH2,KIAA1161,MECOM,SNX18,NECAB3,OPN3,CTPS1,PIKFYVE,CTSD,EEF1D,TMED2,DNAI1,EPB41L5,PMPCB,DDB2,B3GNT7,KIAA1841,ZNF84,MMD,MICB,AMER1,PIP4K2C,KDM3A,RASA1,FAS,PRKAG2,TMEM54,NAB2,SLC4A3,TCEAL4,PCDH19,NRBP1,IRF1,PKD1L2,PLEKHG3,ELK4,FRMPD3,PLA2G4A,TRIP10,TMEM217,S100A11,CAST,SUZ12,IQGAP1,RPS6KA1,RNF182,EGR3,NUDT12,TMPRSS4,GNB2,SLC25A35,APLP2,FAM46A,DOK4,TNPO2,CDKN1B,DAB2IP,PHKA2,NR2C1,GPX4,TBC1D10B,SLC5A11,TEP1,PRKCQ,C15orf39,H2AFV,ZNF469,NIN,OSBPL2,JAK1,KIAA1804,NRG1,B4GALT3,ATMIN,DENND5B,OTUD5,NUDT6,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,CDCA3,ARL4C,GPR180,APOBEC3H,PNPLA5,TMCC3,SNTA1,AKIRIN1,OXCT1,PHF7,MGAT1,SGK3,PRC1,ATP8B1,ERCC2,CNOT6L,OSGIN1,PCCB,CASK,SHMT1,TEF,DENND1B,MPP1,FURIN,VAMP3,C1GALT1C1,LRRC1,NUCB1,RGS9,PRDX3,RCBTB2,SLC25A40,PGM2L1,CSTF2,ETAA1,SLC25A38,CPEB2,OCLN,NMRK1,FLYWCH2,CAMKK1,UBE2Z,TAF6L,CACNB4,KREMEN1,TMC1,DENND2D,PTCHD4,SH3KBP1,ABCD4,NKAIN3,LRRC6,IMPAD1,PHTF1,KIF22,RAB20,SUN3,NFU1,MYH14,PTPRE,TRIM8,SYNE3,ROR1,ADRBK2,TCN2,EDNRA,MDK,CXXC4,ZNF114,UEVLD,IARS2,TRIM45,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ASL,PHLPP1,OTUD1,KCNN4,SIMC1,PARD3B,GYLTL1B,FBXO8,EGFR,GLCE,GNAS,FECH,TSC1,ONECUT1,CDCA5,NFKBIA,ALPK3,RHOBTB2,YOD1,KIF12,PROM2,FAM92A1,ABCG4,TDRKH,ARHGEF16,SS18,SLC25A48,KHNYN,FRYL,SMO,RPN2,STEAP3,GOT1,LOXL1,F2R,SCYL3,FRS3,SUSD3,MAP3K3,GCA,ZNF525,IGSF8,ERBB2IP,BFSP1,CANT1,PPP2R2D,CCDC24,CDS2,SORT1,FRMD6,JKAMP,ARMC7,FAM134A,TRMT2B,FAM167A,IRF2BPL,SNX13,MDM1,MLPH,GALNS,BRD7,CKS1B,RAB3B,PHLDB3,OGDHL,MBNL3,LRRC66,SPAG1,C2orf70,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,SNPH,ZNF596,IBTK,GRIK2,AK7,SLC25A13,RET,TRAPPC8,BAIAP3,LACTB2,ISOC2,SNX9,CARD10,LTBP3,ZNF275,NPM2,CDKN2C,NAPG,MUC4,CLDN4,CRY2,TMEM37,WBP4,RNF26,TIAM1,TIPARP,MGAT5,DSTN,CDA,TMEM98,TMEM151A,PRKAR2B,GINS4,CARHSP1,PLCG1,BOLA3,ENPP1,CELF5,ATP7B,FAM114A1,TRAF3IP1,HDAC1,RNASEL,ITPKA,HSPB1,SCN5A,COX6C,CCDC64B,RABGGTA,TFAP4,MARCH8,FLII,FLRT3,RIMS3,MEGF8,FBXO7,RANBP1,PCYOX1,USP38,CADPS2,SLAIN2,FAM84B,ALPK1,ZMYM1,KANK3,DGKG,ULBP2,MYLIP,PHKG2,PAQR7,HPS3,PQLC3,SHARPIN,KIF20B,SFXN5,GNA11,PSMA4,IL1R1,FNTA,APMAP,S100A5,CLMN,TMEM159,DOCK9,ADAMTS16,TPRN,NQO1,LFNG,APOO,RHBDL3,PTTG1,GRK6,FAM91A1,MOCS1,REPS1,APPBP2,RCN1,ST5,CDH1,SH3BP1,XYLT2,DLG3,LRP11,RASGEF1A,SNX10,ETV4,TMCC2,MX1,TMEM200B,SEC61B,COL6A2,PFKFB2,GIGYF1,EBF2,CCNB3,PNPLA6,DMWD,ISOC1,MAPK12,FAM189A2,GCAT,TRAF2,OSGIN2,PLPPR4,SLC25A43,IFT27,CTNNBIP1,ZFX,SLC25A45,PDCD10,FUT2,ITGB8,KNDC1,TMEM62,FAM20B,ZFAND4,RAG1,PARP9,ADAMTS2,PLSCR1,CXorf57,UBE2A,C4orf27,PROM1,PLOD2,DBI,PPM1H,SSNA1,ITGAV,CMPK2,OSR1,CD81,TMEM131,PHC1,CCNI,ILDR1,LMCD1,DNAJB11,TEX2,ITPR2,GALM,SPTB,FANCI,SUSD2,CPNE2,TM9SF2,CTNNB1,NPNT,IL6ST,PSMC2,PAPSS1,MITF,SLC44A1,PLK1,THRB,KCNIP3,CELSR2,CKAP2L,CCBL2,NKAIN1,EAF2,SESN1,KDM4D,TNS4,HS6ST1,PLEKHG6,KLF12,ZNF367,KPNA2,TTC39C,TC2N,MYL12B,RRAGD,HS6ST3,RMND5A,HJURP,DNAJB2,PDCL,SORBS3,ADCK5,RAB6A,FBLN1,ANO1,MYO5C,UBE2Q2,WNT3A,MPHOSPH9,CKAP4,PLEKHA6,BTNL9,RGMB,MGAT4B,ZNF320,SCRIB,BCL2L13,C18orf8,NMT2,FOXD2,RASGRP2,FA2H,SLC2A6,P4HA3,ZDHHC7,ZDBF2,RAD21,TP53,P2RX7,BAHD1,STIL,EMP2,SYTL2,TTC21B,PDGFA,WDR44,PPME1,ESPN,NOTCH3,LMAN1,ERLEC1,CCSAP,SERTAD3,DAG1,TAPBP,PTGS2,PAFAH1B3,RBL1,ABHD12,MMP17,STK38,EFNA5,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,FAM134B,BIN1,CMAS,DYRK3,CPEB4,SCD5,CTSB,HAL,ERI2,ERCC6L,GDF15,AIP,LBR,VPS26A,PARM1,IL22RA1,FZD6,SH2D4A,NRP2,M6PR,CD109,CDK16,ALPP,FAM63A,TFAP2A,SGK1,TRIM21,HMGCL,SYK,LRRC24,P2RX4,HES1,MOSPD2,GUSB,PLAUR,CRIP2,PRICKLE1,STMN3,MAML2,TXNDC11,BBS2,RNPEP,DGKE,USP6,BCL10,CNOT2,DDAH1,FGF18,E2F1,SH3BGRL2,ICOSLG,ARHGEF9,ARHGEF4,GOLGB1,LAMP1,FAM171B,VANGL1,TSC22D3,CUL1,PDGFRL,OAT,SEPT4,CYP1A1,ZNF823,STIM1,PIK3CA,POLL,MARCH2,ARMCX6,METAP2,ACVR1C,CDYL,LDB2,POR,RAB2B,PRIM1,GDE1,PPP2R4,PRDM5,MAPK13,WBSCR27,SEMA6B,MRC2,SCOC,DHPS,PRKAA1,AKAP17A,APBA1,S100A2,TNFRSF19,PDXDC1,TSPAN7,CALR,RALGPS2,ZNRF2,VASN,TPST1,DAPK1,DLX4,ZNF117,KCTD3,SOCS5,SPATA20,KCNJ12,LPGAT1,CALM1,WHSC1,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,FAAH,PELI2,ZDHHC20,MATN2,ARAP1,MPP2,FAM83D,CABIN1,PLIN3,IFIH1,HOOK1,MFSD3,KIF3C,SPRED1,GPR107,REPS2,CAPN12,DLGAP5,TCTN2,ST14,CERCAM,RALBP1,NDRG1,THRA,CCDC110,BLCAP,FTH1,TMEM170B,BCL2L1,DDR1,FLT3,ART5,ZFYVE9,C11orf84,APOBEC3B,CD46,RALB,RNASEH2A,EPHB4,TSPAN1,FLOT2,COG2,FOXJ2,CLSTN1,TMEM144,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,TSPAN18,HAGHL,FAM195A,SLC27A3,COBL,PRKAR1A,PLSCR4,CENPI,PBX3,NES,CBLL1,DNAH3,HLA-A,CKAP5,FUT8,DRAM1,ERBB3,MSH6,TGIF1,B3GNT2,ZWINT,LONRF3,PAPD7,TCFL5,FBXO9,YES1,AIF1L,GRTP1,FOS,CRTC2,CDK5RAP1,SEC14L4,ABCB1,FZD5,WDR91,MELK,UGT8,MAP1LC3B,ECI1,HTR1D,ADPRHL1,SIPA1L2,RAB15,SIVA1,CEP78,CTTN,SP5,STK35,LAMP3,TRAPPC13,LAP3,USP18,ACBD3,ARHGDIB,GPRC5B,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,CD99,PPP1R12A,ASB9,FAM81A,QSOX2,B3GALNT1,TYW3,SPP1,FAM20C,SRP54,HLA-C,NPTN,ZRANB1,SLC12A2,CCDC88A,TPGS2,ELK3,PODXL2,VWA1,HEATR5A,PDIK1L,MFSD7,RHPN1,INSR,TMEM30A,SH3BP4,DONSON,SHROOM2,JAK3,APOL2,COL16A1,DRD1,LMO7,CCNE2,SOD2,OSR2,EXT2,KCTD9,SAP130,CYP4F11,REEP1,ECE1,ETHE1,UPF3A,SEPHS1,EBAG9,PTPRU,BTBD19,TMTC2,CD40,HSF4,ALDH5A1,STAT6,PTBP3,RCAN2,LNP1,KDELC2,GLIS3,ENO2,ARHGEF11,TSPAN15,SHPRH,SH3D19,SERPINB9,COL4A5,INTS8,TRIB2,RBP7,ITGA2B,HMGXB4,SYDE2,HDAC9,TOP2A,MZT2A,CARD8,ADRBK1,TAF1B,LLGL2,A4GALT,ACTA2,H2AFY,KANK2,CLIP2,RPGR,SLC35A1,RBMS2,B3GALT6,WNT10B,RUNX3,FAM73B,NDRG3,FOXL1,CD8A,SWAP70,RND3,CSGALNACT1,PLOD3,AHR,RAB3IL1,ABCG1,CD33,TRIM24,ADD1,AASS,MRPS15,XIAP,FBXO2,MMADHC,DHX8,LGI3,KIF26A,CA8,EPDR1,TP73,CALM2,WEE1,PQLC2,ARHGAP42,RGS12,PSMD1,DNAH6,CABP1,PPP1R16A,ALDH1A3,TUBG1,PIK3CD,TINAGL1,ACOX2,APOBEC3G,ERAP2,SMARCA2,SH3BGRL,LOXL2,ICMT,PPP1R14C,SLC44A3,PGF,LIMK1,MAP3K11,SERPINB6,MRPS28,RELL1,E2F8,GAB1,HOXC13,NFKBIE,CYP2J2,STRN4,ZNRF3,MERTK,ELF3,RAVER2,GNS,WDFY1,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NCAM1,EPHX1,SLC37A1,CALCRL,PLS1,MEST,SPTLC2,RHOB,PTPRF,SCARB2,DYSF,OSMR,MDH1,ARPC2,SERPINB1,RPS6KA3,CSRP2,XDH,ARHGAP11A,MTM1,PAPSS2,GRHL2,GALNT12,FAM131C,WDTC1,PKP2,TESK2,PRKACA,APC2,ZNF385B,UHRF1BP1L,SP100,DACT1,SSH3,PSRC1,LGALS8,SYNE2,NUSAP1,IRS2,TTC12,SIPA1L1,INPP4B,PLEKHG1,TTC8,FARP1,PDIA3,PKN1,NUCB2,KCNC4,GSTP1,HOXB2,PDIA4,NEO1,ANK1,IRAK1,CTSC,ANKS1B,CALD1,FDXR,ECI2,ADAM15,MAPK11,WWP1,NPTXR,SGCB,S100A6,CRTAP,AMOTL2,FMN1,CTNNAL1,BCL9,GRIN1,MYEOV,CRISPLD2,ABLIM2,GALNT3,BTG1,KIAA0141,ZFP30,CENPE,NUP37,USF2,FOXA1,DCBLD1,MYL9,SIGIRR,FAM199X,CUL4B,FHDC1,MCCC1,NDC80,CDIPT,PIGL,SDC1,CNTRL,LMAN2L,DDHD2,DUSP10,TLN2,PXMP4,MYBL1,S100A13,ZNF462,CD55,ING1,HN1L,C12orf65,EZR,KLK6,PRKRA,IDH1,ZBTB7B,OPTN,PLCH1,MSL1,WIPI1,DOLPP1,PRKCDBP,CTNND1,TTC9,PIEZO1,EPB41L4A,GLCCI1,CHCHD7,RACGAP1,CNTNAP2,B4GALT4,C3orf18,IL18R1,SSX2IP,CORO1B,RB1,VASP,DAZAP1,IGF1R,TMEM8A,PSMA5,ABCC1,CHSY3,CYP26B1,MRPS33,WDR72,TCF7,IFIT3,MAPKAPK2,PVRL2,ITGA7,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,RNF146,UPF3B,FOXM1,XYLT1,ZNF28,FAM198B,CCNL1,SLC7A2,LPIN3,SDF4,PER2,SRPX,EFR3A,LHX6,PLCG2,SCN2A,MINPP1,DVL2,CPD,MBP,FIGNL1,COQ10B,DNAJC10,PTK7,ADAMTS14,ANXA9,ZBTB6,LTA4H,NDST3,CMTM4,GSDMD,MACC1,BLVRB,SELL,GABRG2,JAG2,DSE,CRABP2,GBX2,CCDC92,MAGEE1,ABCD1,KLF9,TLE6,FAH,HMMR,DLGAP1,PSMB4,PPARA,CAPNS1,TRIM35,NPDC1,BSDC1,MAPK8IP1,SCRN2,PRDX4,CD83,CDKN2AIPNL,FAT4,SERPINA1,CDCA7L,NMI,CLIP4,PKD2,ACADM,SUN1,GAA,TTC39B,FAM129B,PPFIBP2,TAP1,GATA3,FAM101B,CENPN,CHST2,NCS1,ELMO2,IQCE,PRICKLE3,RGS3,ATRNL1,MTMR11,PACSIN1,ORAI2,KIFC2,NBPF3,MGAM,AURKB,SAV1,MCFD2,SLC25A5,ZFAND5,ULK2,SGPP1,AHRR,SLC25A4,AREG,GNPTAB,FAM110C,UNC5B,RTN3,DDX58,INPPL1,FRMD4A,HLA-E,PRRG4,BMP2K,ITGA3,CYR61,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,TSPAN33,RIMS2,IGSF3,QSOX1,FADS2,MFI2,B9D2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,PKM,GLT8D2,FBXO10,FRMD4B,DGKH,GABRD,SERTAD2,ISM1,DCK,FGD6,NR4A2,MAP3K5,SLC2A4,ARMCX3,CEP70,NLRX1,BROX,IRX4,KCTD12,AIFM2,MNS1,ZNF75D,CNNM4,IFIT1,LGMN,TMBIM1,MYO5B,SEC23A,CDKN2AIP,CAPN6,TMEM43,LYRM1,COX11,SLC11A2,AKR1E2,SP4,CMTM7,PRDM11,EPHA10,FYN,PPP2R5A,ACYP1,STAT1,PPP1CB,SLC27A1,KLF5,ZC3H12B,HS3ST3B1,MLKL,NR3C2,MRPS9,WASF3,JRKL,ATP9A,CCNJL,CYB561,SEPP1,SPR,SIX4,LGALS3BP,FAM111A,C16orf59,PTEN,CENPJ,SLC44A2,TAGLN2,MAP3K7,GFI1,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,PARP4,GPLD1,MAMDC4,CTNS,AMMECR1,CCDC69,SERPINB5,GRIN2D,NCAPG2,ARSB,USP16,JARID2,ESYT2,EXPH5,EMX1,CASP3,LTBP1,TMEM184B,ST13,CPT2,EPHX4,KIF2C,DNER,TSEN34,CHPF,ARHGEF10L,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,AKR1B1,POF1B,RP2,ARNT2,SLC39A10,TECR,FGFR1OP2,RASGRP1,OLFML2A,TDP1,FOPNL,RNF165,PTGFRN,STK17B,SEC14L2,LRRC42,ARHGEF19,NEIL1,FASTKD1,CCDC74B,ADIPOR1,LEMD1,APBA2,MIIP,PSMC1,GRN,FAM213B,ELOVL7,SAMD9,ZNF432,AIM1L,CA2,LRRN2,FNIP1,FXYD5,ZNF692,KNTC1,NCEH1,ACAD8,LRIF1,ALS2CL,KDELR1,OXR1,BTN3A2,RNF113A,AMDHD1,MUM1L1,XKRX,BCAR3,NUDT16,SLC6A6,UTP14C,CGREF1,PAPD5,EGFL7,PITPNA,KLF7,FBXW5,GAS2L1,SLC25A24,ZSWIM5,IL15,PSME2,SLC2A8,GMPR,MORC4,MICALL2,PATL2,LRRC45,SETDB2,TWIST1,PDIA6,HSPA2,TAF5,BAG4,KREMEN2,OSTM1,SNAPC2,DUSP4,DOCK5,MAP3K6,BHLHB9,PEX2,VSIG10,PLXND1,AKNA,SGOL1,LIFR,CBX4,ANXA3,POC1B,LRP4,MIER3,AES,NOTUM,POMGNT1,ZNF212,SAC3D1,IL17RB,ADORA1,KIAA0319,TRIM3,HSPA13,IQGAP3,SUN2,SYPL1,ADAM17,ASPM,DEPDC4,GCLC,NR4A1,POLD3,MPV17L2,MAP1B,KLHL2,HLA-B,DHRS2,HNRNPH2,PRCP,TADA2B,UBE2D2,HOXB13,GEM,LRRC57 |
| 5.990e-04 | -7.42 | regulation of anatomical structure size | biological process | GO:0090066 | 383 | 81 | 16441 | 2455 |
SSH1,ADD1,RET,ARFGEF1,WDTC1,SOD2,P2RX7,PLXNA1,SPTB,HTR1D,TP73,CDKL5,DPYSL2,CAPG,DLG1,DNM2,SEMA3G,CTTN,NEB,SEMA3B,SSH3,CLCN3,SOD1,BAG4,AKT1,DMTN,DSTN,EZR,ULK2,EDNRA,LIMK1,TRIOBP,EFNA5,SPTBN5,NRG1,TMOD2,PLXND1,ARF6,F2RL1,SEMA6B,GCLM,EPS8,CRABP2,ICAM1,SPP1,VASP,ADORA1,PTEN,MEGF8,KCNN4,PRKG1,ACTA2,TNFRSF12A,NTN1,WNT3A,IQGAP3,SLC12A2,HP1BP3,P2RX4,RHOA,RAB3B,FMN1,GCLC,ANO6,PLS1,ILK,BBS2,RASA1,CDK5R1,MAP1B,TSC1,SWAP70,PLEKHH2,SEMA4D,PLOD3,ARPC2,SHROOM2,SEMA3A,L1CAM,RARG,DRD1 |
| 5.994e-04 | -7.42 | CHIBA_RESPONSE_TO_TSA_UP | MSigDB lists | CHIBA_RESPONSE_TO_TSA_UP | 51 | 17 | 17758 | 2588 |
QSOX1,TIMP2,CASP9,ARHGDIB,TP53I11,FOS,HLA-A,CDKN2C,TIMP3,ANK1,CTGF,ITGA3,SIVA1,ITGA7,FOSB,CD9,IGFBP2 |
| 5.994e-04 | -7.42 | TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | MSigDB lists | TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | 51 | 17 | 17758 | 2588 |
ACVR1,ACVR1C,TGFBR1,PDGFRL,ROR1,MERTK,FLT3,DDR1,EGFR,NRP2,INSR,IGF1R,ACVRL1,AXL,PTK7,RYK,ERBB3 |
| 5.994e-04 | -7.42 | MORI_PLASMA_CELL_UP | MSigDB lists | MORI_PLASMA_CELL_UP | 51 | 17 | 17758 | 2588 |
ARMCX3,CTSB,HTATIP2,NANS,PRRC1,FAM46C,DNAJB9,M6PR,TRAM2,DDOST,RRBP1,SLC44A1,HSPA13,SPCS3,MANF,LMAN1,TMED2 |
| 6.014e-04 | -7.42 | AACTGAC,MIR-223 | MSigDB lists | AACTGAC,MIR-223 | 93 | 26 | 17758 | 2588 |
SPRED1,PHF20L1,CDK17,SEPT6,UBE2A,FBXO8,ATP1B1,ALCAM,NFIB,TSPAN7,RHOB,RASA1,MAP1B,IGF1R,RALGPS2,STIM1,CSNK1G1,IL6ST,DUSP10,STK39,EFNA1,PDE4D,TMEM64,WDR62,SCN3A,ATP2B1 |
| 6.014e-04 | -7.42 | MODULE_174 | MSigDB lists | MODULE_174 | 93 | 26 | 17758 | 2588 |
MYL9,P2RX4,WASF3,TRIP10,FOXM1,FXYD3,SOD2,GDF15,ATP1B1,ETS1,LGALS3BP,IER3,DGCR2,MGAT1,SEMA4D,SECTM1,MYLK,DNM2,RAB31,TAX1BP3,NRG1,PIEZO1,PDXK,LGMN,DRP2,TOB1 |
| 6.071e-04 | -7.41 | single-multicellular organism process | biological process | GO:0044707 | 6192 | 997 | 16441 | 2455 |
DOC2A,HECA,ADD1,AK7,GRIK2,RET,MCOLN3,HEXB,NRG2,IL18,KIF26A,BARD1,LTBP3,GRM5,TP73,NPM2,CDKN2C,CALM2,WEE1,PSMD1,TGFBR3,MUC4,PAQR5,ALDH1A3,SLC46A1,RDH14,KLF3,DNM2,CLDN4,CRY2,PIK3CD,SEMA3G,PPP1CA,TIAM1,CPE,TIPARP,ERAP2,TUBA4A,SMARCA2,SPEF2,TFAP2C,PRKAR2B,LOXL2,F12,ICMT,RNF19B,MYOM1,PNKD,ARF4,COL12A1,GINS4,ABR,PGF,PLCG1,ENPP1,DNM1L,LIMK1,ATP7B,TRAF3IP1,MYLK,NOD2,HDAC1,SERPINB6,TMOD2,ITPKA,LSM14B,ARF6,HSPB1,GAB1,E2F8,HOXC13,SCN5A,TMTC3,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,RABGGTA,ELF3,FLII,RAC2,FRY,MEGF8,FLRT3,ZIC5,NEK2,USP1,MYDGF,CNGA1,NCAM1,DGKG,MYLIP,NDUFA12,PAQR7,REC8,UFD1L,SALL4,SHARPIN,FHL2,CALCRL,PLS1,KIF20B,NPHP3,ILK,TP53INP2,DPYSL4,GNA11,PSMA4,RHOB,PTPRF,NCOA3,ETS2,HTT,TIMM8A,SEMA4D,ITPR1,DGAT2,CLMN,AURKA,STK39,B4GAT1,GDF11,CFAP20,NDE1,DRP2,ARPC2,CBX5,TRPC3,RPS6KA3,TMEM173,CSRP2,DOCK9,DMPK,XDH,ADAMTS16,EGLN1,TPRN,PAPSS2,GRHL2,LFNG,INPP5D,WDTC1,PKP2,PRKACA,APC2,TNFSF9,RCN1,CCND1,SCNN1A,CDH1,DACT1,RTKN2,ACSL4,DLG3,LRP11,RASGEF1A,CDKN2D,MYT1,SNX10,ETV4,SCN3A,ENPP4,SSH3,CAMSAP3,COL6A2,LGALS8,FZD4,SAT1,HTATIP2,TANC1,EBF2,NFIX,IRS2,PDLIM3,SHROOM3,SLC9A6,CORO1C,AXL,WFS1,SIPA1L1,WWTR1,PNPLA6,RGS14,ARNT,MAPK12,TTC8,CTHRC1,NKX3-1,TNRC6C,FARP1,MAN1A2,DCAF7,SDC4,HABP4,CCM2,BIK,FLOT1,BTN3A1,GMCL1,CTSZ,PKN1,PLPPR4,ZNF219,ETS1,GSTP1,NFAT5,HOXB2,SRPX2,ICAM1,SGPL1,NEO1,CTNNBIP1,CAPN2,ZFX,ANK1,PDCD10,IGSF9,ITGB8,CALD1,KNDC1,KCNK5,GPC3,CST3,BAX,ADAM15,TMBIM6,WWP1,AK3,RAG1,SGCB,ITM2C,S100A6,POU6F1,ADAMTS2,LCA5,PLSCR1,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,GRIN1,UBE2A,AK4,SNTB1,CRISPLD2,ABLIM2,TXK,CNTNAP1,PITX2,LDLRAP1,PROM1,ACVRL1,RAB11FIP2,DBI,FAM3C,NR4A3,CENPE,ITGAV,FHL1,OSR1,USF2,SHOX2,FOXA1,PHC1,TLL2,MYL9,EPAS1,AGRN,CUL4B,EPHA4,SUDS3,ARFGEF1,PHOSPHO1,NDRG2,F11R,ITPR2,PDGFB,SDC1,SPTB,SLC9A3R2,PLS3,RPS6KA2,PCNA,CTNNB1,NPNT,SHC3,IL6ST,MITF,PSMC2,PAPSS1,ELF5,TMEM143,DUSP10,TNFRSF18,NTN4,S100A13,NEB,THRB,CD55,KCNIP3,MARK1,CELSR2,NFE2L1,CR2,EZR,ARFRP1,KLK6,ANLN,PRKRA,IDH1,ZBTB7B,CLCN2,CDK1,RHEB,PLEKHB1,OPTN,DPYSL3,IRX3,HS6ST1,TRAM2,KCNMB4,MAP2,HOXA9,PRKCDBP,POMT1,MAFF,MYL12B,RUNX2,USH1C,LGALS3,RASA2,PDCL,PSMD7,SORBS3,RACGAP1,CNTNAP2,NCKAP1,DOCK11,FBLN1,DHRS3,PGAP1,IL18R1,ANO1,CORO1B,BMP2,TNS3,RB1,VASP,DAZAP1,TIMP1,IGF1R,GATA2,FRAS1,KIF13B,PAK2,PIM1,WNT3A,NTN1,PLCB2,ALDH3A2,PSMA5,CYP26B1,DPYSL5,PCDH1,RGMB,TCF7,SCRIB,EIF2AK1,UNC45B,G2E3,PRX,SMN1,CDK5R1,RASGRP2,MAPKAPK2,MOSPD3,FA2H,COL13A1,PHLPP2,ITGA7,CSF1,PRPS2,ATP1B3,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,P3H2,TP53,DGKA,P2RX7,ERBB2,RASGRP3,SLC7A2,STIL,EMP2,SDF4,PER2,IER3,TTC21B,PDGFA,TACC2,LMO4,PLCG2,LHX6,SRR,PLK4,BCL6,GYS1,CDH3,ESPN,NOTCH3,SCN2A,MINPP1,LMAN1,GM2A,DVL2,SULF2,SIRT1,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CDC20,CCSAP,PTGER4,ACO1,MYL12A,DAG1,PTGS2,DUOX1,ATP1A1,RTN4RL1,IDE,PTPRJ,PAFAH1B3,ABHD12,PTK7,PSMD3,ADAMTS14,CHMP4B,EFNA5,IRF7,RPL22,LTA4H,POMGNT2,CTDSP1,FAM134B,BIN1,COL9A3,DYRK3,CDH22,CD63,ADGRG1,CTSB,GNAL,MCTP2,SELL,GABRG2,PSMD10,JAG2,CRABP2,FZD6,PPP2R3A,NRP2,SIRPA,GBX2,ZDHHC21,CD109,FOXP2,CDK16,TFAP2A,SGK1,ALDH7A1,HMGCL,SYK,CAMK2G,FAM134C,TLE6,ATP2B1,GCNT1,DUSP1,P2RX4,HES1,RHOA,PSMB4,PLAUR,CRIP2,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BBS2,RNPEP,BCAR1,DGKE,PRDX4,BCL10,CNOT2,DDAH1,FAT4,SERPINA1,SCG2,TWSG1,FGF18,PGRMC1,E2F1,PKD2,PPP2R3C,GAA,ACVR1,HSPG2,SSH1,LGR4,VANGL1,ATP8A1,TMEM41B,KLC2,CUL1,GATA3,PSME1,CAMK1D,PLXNA1,CCNB1,VASH1,PJA2,SEPT4,OAT,FAM101B,CHST2,PICK1,NCS1,TYMP,CYP1A1,CTGF,STIM1,IL31RA,POLL,PIK3CA,IRF2,TACSTD2,ZBTB18,PACSIN1,LAMP2,SGCE,ACVR1C,CASP9,MGAM,AURKB,LDB2,CCNF,SAV1,ZFAND5,ULK2,SFXN1,HLF,AREG,PLK2,TBX1,LRIG1,NKD1,BMP1,DHTKD1,EIF4EBP2,SERPINI1,SPRY4,TANC2,UNC5B,F2RL1,LZTS1,FGD1,DLAT,SEMA6B,KLF2,INPPL1,MRC2,CDKN1C,DGKQ,SLC25A27,KIF23,NOTCH2,SLC1A3,HERC6,APBA1,TNFRSF19,S100A2,KIAA1161,MECOM,CALR,DOPEY2,ITGA3,CYR61,BHLHE41,MSH2,PRKG1,SORL1,OSTF1,TNFRSF12A,CACNA1D,PIKFYVE,CTSD,DLX4,TMED2,GPR161,RIMS2,IGSF3,DNAI1,SPATA20,EPB41L5,GFPT1,KCNJ12,MMD,CALM1,AMER1,DCHS1,ANO6,WHSC1,VEZT,EPHA1,NFIB,STX3,RASA1,PDE11A,FAS,DGKH,MMP15,GABRD,MATN2,NAB2,FAM83D,PCDH19,NR4A2,EFNA1,PER3,HOOK1,EHD1,IRF1,PLA2G4A,FOXO6,SPRED1,KIF3C,TCF25,ST14,THRA,CAST,RPS6KA1,IQGAP1,NDRG1,IRX4,BCL2L1,EGR3,DDR1,FLT3,CYP39A1,MNS1,EPM2A,CD46,NOV,APLP2,CCNA2,DOK4,CDKN1B,CNNM4,DAB2IP,PDE4D,EPHB4,LGMN,MED30,SEMA3B,GPX4,MYO5B,DMTN,UTRN,COX11,PRKCQ,SLC11A2,ATP1B1,PYGO1,ITPR3,ALCAM,FZD7,CMTM7,EPHA10,FYN,JAK1,NGFRAP1,STAT1,PPP1CB,RAB29,NRG1,KLF5,PRR15,CBX7,COBL,PRKAR1A,WASF3,PCOLCE,JRKL,HAPLN3,CENPI,EPS8,PBX3,NES,SEPP1,SPR,FGF19,EFNB1,TEAD3,ADGRB2,SIX4,RND1,SNTA1,E2F7,OXCT1,MGAT1,PTEN,FJX1,FUT8,CD9,ATP8B1,ERBB3,ERCC2,MAP3K7,CITED2,TTPA,GFI1,SPRY2,NCOA2,OSGIN1,MSH6,FARP2,RASGRF1,TGIF1,PDGFC,ARHGEF28,B3GNT2,TCFL5,VAMP3,FURIN,DIAPH2,C1GALT1C1,YES1,FOS,KIF11,GPLD1,CDK5RAP1,RGS9,TIMP3,CTNS,DGCR2,FGFR2,PRDX3,TBX18,RYK,ERAP1,SERPINB5,GRIN2D,LRRK1,GPER1,FZD5,WDR62,ARSB,NCAPG2,SLC25A38,MELK,RGMA,JARID2,EXPH5,EMX1,CASP3,UGT8,CRYM,UBE2Q1,MPP5,PLAC1,KIF2C,CACNB4,DNER,TMC1,HTR1D,EPCAM,LRRC6,GRHL1,CDKL5,DPYSL2,IMPAD1,DLG1,AKR1B1,TRPC1,KIF22,ASH2L,RP2,CTTN,MYH14,ARNT2,BTBD3,IL1RAP,SP5,RASGRP1,CYP1B1,ATL1,SOD1,TRIM8,ASXL1,RNF165,ARHGDIB,EDNRA,CXXC4,MDK,GPRC5B,HPSE,TDRD7,TRIM45,NRGN,APBA2,PPP2R5D,PSMC1,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,DUSP5,SPP1,CA2,LRRN2,FAM20C,KCNN4,OCRL,COL6A1,EBF4,PRKCI,SUCO,FNIP1,NPTN,ETV7,SLC12A2,CCDC88A,MDFI,ELK3,OXR1,HMG20B,PDE5A,VWA1,BTN3A2,C3orf58,RANBP9,EGFR,FECH,GNAS,BCAR3,ONECUT1,TSC1,INSR,PLPP3,TMEM30A,UTP14C,ALPK3,PITPNA,DONSON,EGFL7,SHROOM2,JAK3,RARG,COL16A1,APOL2,DRD1,KLF7,DYNLRB1,SORBS1,PAX6,IL15,PSME2,HDAC11,SOD2,COL18A1,MRAS,OSR2,MICALL2,PHLDA1,EXT2,MXD1,SS18,KCTD15,ARTN,SETDB2,CYP4F11,FRYL,KIF14,SMO,DIXDC1,TWIST1,ECE1,NFKB2,LOXL1,F2R,FRS3,MAP3K3,SOAT1,PTPRU,OSTM1,IGSF8,GLO1,CD40,DUSP4,ARHGAP35,SOCS3,HSF4,ALDH5A1,BFSP1,BHLHB9,STAT6,PEX2,TLE1,PTBP3,OVOL1,RCAN2,SPTBN5,PLXND1,ABCA1,LIFR,GCLM,ANXA3,SORT1,ARHGEF11,POC1B,ARHGEF7,CIT,LRP4,TGFBR1,COL4A5,AES,NTAN1,ITGA2B,HDAC9,KIF5B,TOP2A,MDM1,ADRBK1,ADORA1,LLGL2,BMP7,MYCL,RRBP1,TOX2,KIAA0319,ACTA2,ARVCF,TRIM3,MTURN,RPGR,MYO5A,ADAM17,WNT10B,GCLC,NR4A1,ASPM,RC3H2,MBNL3,RGCC,TTC7A,RUNX3,FAM73B,FOXL1,LEPR,MAP1B,ARHGAP24,LEMD2,CTSL,CD8A,SWAP70,PRCP,DHRS2,CTSV,SPINT2,CSGALNACT1,ARRB1,HOXB13,PLOD3,SOX8,ZMIZ1,L1CAM,AHR,ABCG1,NGEF |
| 6.075e-04 | -7.41 | antigen processing and presentation | biological process | GO:0019882 | 213 | 50 | 16441 | 2455 |
UNC93B1,KIF3C,SEC61G,HLA-E,PSME2,HLA-F,KLC2,PSMD7,TAP1,PDIA3,KIF23,PSMD10,RACGAP1,PSME1,KIF2C,RAB6A,KIF26A,BCAP31,ICAM1,HLA-A,MARCH8,CALR,PSMD1,AP1M2,PSMC2,DNM2,KIF22,HLA-C,CTSD,LGMN,PSMA5,ERAP2,SEC23A,SEC61B,RAB3B,PSMB4,UBE2A,KIF11,PSMA4,DCTN6,CTSL,HLA-B,TAPBP,CD8A,PSMD3,CTSV,ERAP1,ITGAV,CENPE,PSMC1 |
| 6.078e-04 | -7.41 | GTPase activator activity | molecular function | GO:0005096 | 257 | 58 | 16491 | 2452 |
ARHGAP11A,ARAP3,DEPDC1,ARHGEF11,TBC1D1,RASA2,RALBP1,IQGAP1,ARFGEF1,RGS20,RASGRP3,RACGAP1,ELMOD2,SYDE2,SIPA1L2,ACAP2,ARHGAP42,RGS12,RABEP2,LLGL2,RINL,SH3BP1,OCRL,RGS3,TBCD,FAM13B,RANBP1,RGS5,DAB2IP,RP2,IQGAP3,ALS2CL,TBC1D10B,DOCK4,ARAP2,TBC1D8B,RAPGEF2,ARHGDIB,GRTP1,ABR,RASA1,ARHGAP35,ARHGAP24,PLEKHG6,RGS9,ARHGEF19,TBC1D17,SIPA1L1,RIN3,ARAP1,ARRB1,AGFG2,ARFGAP3,ARHGAP4,RGS14,TBC1D4,RAP1GAP,STARD13 |
| 6.095e-04 | -7.40 | Tetraspanin | interpro domains | IPR000301 | 30 | 12 | 18293 | 2672 |
TSPAN15,CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN13,TSPAN1,CD81,TSPAN17,TSPAN7,TSPAN33 |
| 6.096e-04 | -7.40 | MODULE_16 | MSigDB lists | MODULE_16 | 497 | 99 | 17758 | 2588 |
EPAS1,FOXM1,S100A11,INPP5D,RPS6KA1,PTTG1,NDC80,GMPR,NRG2,SDC1,FLT3,CARD10,IER3,CDKN2C,DAPK2,WEE1,ZYX,PCNA,CCNA2,ARTN,SH3BP1,PLCG2,CAPG,IFIT1,CKS2,CYP1B1,CPD,PLK1,LAMP2,CENPA,PTPRU,PFKFB2,S100A4,CDC20,CDA,ARHGDIB,AURKB,PKMYT1,CCNF,PLEKHB1,LCP1,ZMPSTE24,HSF4,AGPAT2,STX10,TBX1,BMP1,GLA,ARHGAP4,FAM189A2,ITGA6,DCAF7,PKN1,ITGA2B,M6PR,TOP2A,CTNNBIP1,RAC2,IRAK1,OXCT1,CTSC,LLGL2,CD22,BDH1,FDXR,TBCD,MSH2,CITED2,MSH6,GPR161,TMX1,HMMR,PIGC,QSOX1,FADS2,ZWINT,MAPKAPK3,PLAUR,MYBL2,PYGL,EMP3,TCF7,GGH,PRRC1,KIF11,RNPEP,PSMA4,CDK5R1,MMP15,SLC6A6,NMI,DTX4,RAB31,ZMIZ1,SERPINB1,UBE2C,ESPL1,JARID2,CD33 |
| 6.098e-04 | -7.40 | ERMFAMILY | prints domains | PR00661 | 16 | 8 | 4759 | 661 |
EPB41L5,FARP1,NF2,EZR,EPB41L4B,EPB41L4A,MYLIP,FARP2 |
| 6.110e-04 | -7.40 | blood vessel morphogenesis | biological process | GO:0048514 | 372 | 79 | 16441 | 2455 |
ACVR1,HSPG2,EPAS1,FOXM1,COL18A1,IL18,EGR3,VASH1,PDGFA,NOV,TYMP,CTGF,CTNNB1,SMO,PIK3CA,DAB2IP,EPHB4,NOTCH3,TIPARP,CYP1B1,SIRT1,FZD4,SAT1,HTATIP2,LOXL2,EDNRA,PGF,PTGS2,HS6ST1,PTPRJ,HPSE,TBX1,MYLK,PNPLA6,KLF5,PLXND1,UNC5B,E2F8,ADGRG1,CCM2,TGFBR1,ETS1,SRPX2,NRP2,SGPL1,GBX2,E2F7,PDCD10,PTEN,CYR61,BAX,ADAM15,TNFRSF12A,MYDGF,MAP3K7,SYK,HES1,ELK3,NR4A1,CALCRL,EPHA1,RASA1,RHOB,GPLD1,ARHGAP24,FGFR2,SCG2,ACVRL1,PRCP,ITGA7,FGF18,ERAP1,EGFL7,PKD2,HOXB13,EFNA1,ITGAV,FZD5,ZMIZ1 |
| 6.122e-04 | -7.40 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP | 191 | 45 | 17758 | 2588 |
KLF2,KIF3C,AGRN,NQO1,IL27RA,BLCAP,FAM101B,PHF1,SDF4,AKIRIN1,CTNNBIP1,ST5,RPS6KA2,CA2,MTMR10,AKR1B1,SORL1,ERCC2,NOTCH3,ZRANB1,SOCS5,MYO5B,CTNNAL1,USP18,DIAPH2,TANC1,ICMT,FOS,ULK2,BSDC1,EBF2,SOCS3,IRS2,ENPP1,COQ10A,NR1D2,CANT1,SLC27A1,IRF7,TMEM159,ABCA1,JARID2,PHC1,ABCG1,NGEF |
| 6.122e-04 | -7.40 | GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP | 191 | 45 | 17758 | 2588 |
FBLIM1,GOLIM4,CNOT8,APOO,PDCL,NDUFA4,FAM78A,DPP8,SNX9,COX7A2,FAM111A,ENTPD4,FDXR,CD9,AKR1B1,PXMP4,PHKA2,BTBD3,CRTAP,S100A6,MCCC2,BAG4,MBP,MRPS33,PSRC1,PTPN18,HN1L,WHSC1,GGH,ARHGDIB,ZDHHC3,DHX32,CTNS,RAB11FIP2,CDK19,NEIL3,OTUD6B,E2F1,CTSA,MDH1,GLA,MELK,RAB3IL1,CSRP2,NXT2 |
| 6.122e-04 | -7.40 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 191 | 45 | 17758 | 2588 |
ST13,DAP,NDRG1,ABCG2,KIF23,MGST2,GRK6,FAM101B,SPSB1,OXCT1,IGF1R,RALGPS2,GATA2,CDK16,IL6ST,CD9,TRIM21,STT3B,RCAN3,MPHOSPH9,PSMA5,SMC4,EPHX1,LAMP2,CASK,CXXC5,MPP1,TNFAIP8L1,RAB3IP,ZFAND5,SESN1,DAG1,CYB5A,ANKRD10,CD8A,TMEM50B,ETS2,WFS1,NAB2,HDAC1,ACADM,AHR,KLF7,JARID2,FAM134B |
| 6.122e-04 | -7.40 | GSE22886_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_TCELL_VS_BCELL_NAIVE_UP | 191 | 45 | 17758 | 2588 |
SIGIRR,ENO2,ITGA6,ARL4C,DGKA,GATA3,BTN3A1,IL27RA,NUCB2,M6PR,ZYX,PSMD1,TIMP1,TBCD,SORL1,FAM102A,IL17RA,KIF22,WWP1,TECR,CTSD,TMEM8A,ETHE1,CITED2,PPP6R1,IFITM3,HMG20B,PRKCQ,ATP13A2,TXK,PLCG1,MSL1,ATP1A1,NGFRAP1,SEMA4D,INPP4B,CABIN1,B4GALT3,NDFIP1,PSMC1,NRBP1,RTN3,TOB1,DEF6,DOCK9 |
| 6.154e-04 | -7.39 | neuron projection | cellular component | GO:0043005 | 888 | 165 | 17570 | 2579 |
DOC2A,LAMP1,GRIK2,KLC2,EPHA4,RET,FBXO2,NDRG2,LGI3,LYNX1,HDAC6,DNER,PICK1,GRM5,NCS1,SH3KBP1,CALM2,CDKL5,IL6ST,CABP1,DPYSL2,DLG1,DNM2,MYH14,PPP1CA,CTTN,PACSIN1,ATL1,ORAI2,SGCE,SOD1,PRKAR2B,ARF4,IRX3,DPYSL3,PIAS3,TRIM9,GRID2IP,MAP2,KCNK1,PLK2,LIMK1,TMOD2,ITPKA,NRGN,LZTS1,LMTK3,CALB2,STRN4,CALM3,SLC1A3,CNTNAP2,ITGA3,CA2,IGF1R,SNX18,FLRT3,KIF13B,EXOC8,AHCY,DPYSL5,CALM1,SHARPIN,KIF20B,ELK1,CYFIP2,ILK,NFIB,STX3,CDK5R1,FAS,RASGRP2,GNAS,PTPRF,IL1R1,TSC1,GABRD,HTT,AURKA,ARPC2,SEMA3A,DRD1,NF2,IQGAP1,MICALL2,PRKACA,NOV,DAB2IP,GOT1,DLG3,SCN2A,CLCN3,TIMP2,MBP,S100A4,SEPT6,CCSAP,SYP,TANC1,ALCAM,DAG1,GABARAPL1,PTGS2,SLC9A6,WFS1,SIPA1L1,STAT1,NRG1,RGS14,COBL,BIN1,ANXA3,PINK1,TAOK2,SORT1,FARP1,CPEB4,ARHGEF7,BACE1,EPS8,LRP4,GABRG2,KCNC4,KIF5B,CAPN2,ANK1,IGSF9,MLPH,ADORA1,PTEN,CDK16,ANKS1B,KNDC1,MAGEE1,CST3,KLC3,CPLX1,MYO5A,HCN3,P2RX4,MOB4,RASGRF1,RHOA,ZWINT,RAPGEF2,GRIN1,VAMP3,STMN3,FXR2,FOS,MAPK8IP1,MAP1B,CNTNAP1,LDLRAP1,SYT7,CTSV,ARRB1,GRIN2D,ACADM,GPER1,CPEB2,L1CAM,ACOT7,SNPH,NGEF |
| 6.156e-04 | -7.39 | regulation of cyclic-nucleotide phosphodiesterase activity | biological process | GO:0051342 | 9 | 6 | 16441 | 2455 |
CALM3,CALM2,MAPK7,AIP,CALM1,EGLN1 |
| 6.168e-04 | -7.39 | TAGCTTT,MIR-9 | MSigDB lists | TAGCTTT,MIR-9 | 229 | 52 | 17758 | 2588 |
CDK17,CPEB4,CIT,LRP4,PSMD7,NKRF,MPP5,ZNF385B,MXD1,KCTD9,CKAP5,E2F7,CYR61,CALD1,FRAS1,MITF,FAM84B,MAP3K7,FAR1,CAMK2G,DVL2,SP5,EPB41L5,THRB,PHF20L1,SMARCA2,CASK,NR3C1,CKAP2L,FAM133B,ERBB2IP,DCP2,DPYSL3,ANKRD10,PLCG1,TIMP3,UEVLD,HNRNPH2,TMEM30A,C1orf21,RAP2C,STAT1,NR4A3,PCDH19,SFMBT1,NFKBIZ,HOXB13,CEP41,CPEB2,RARG,ATMIN,TLL2 |
| 6.186e-04 | -7.39 | V$ETS_Q4 | MSigDB lists | V$ETS_Q4 | 240 | 54 | 17758 | 2588 |
SIGIRR,PAX6,CAST,SLC41A1,ETV5,DGKA,GATA3,NDUFA4,TRMT2B,ITPR2,DOCK11,PKN1,PDGFB,CMTM6,TEAD3,ZNF687,RINL,RGS3,MGAT4A,FCHO1,FXYD5,POF1B,TWIST1,DAB2IP,ACSL4,SCN2A,GFI1,PLCB2,SCN3A,RBMS2,BAG4,MARK1,ELK3,UXT,FURIN,PPP1R14C,SPNS3,LCP1,DDX23,EPN3,KLF12,WDR11,FGFR2,RIN3,MADD,RAP2C,ITPR1,ARAP1,HMGA1,ARHGAP4,DRP2,RGS14,ARSB,STARD13 |
| 6.189e-04 | -7.39 | MARTINEZ_TP53_TARGETS_UP | MSigDB lists | MARTINEZ_TP53_TARGETS_UP | 580 | 113 | 17758 | 2588 |
LTBP1,SLC2A4,SORBS1,ADD1,NDRG1,SLC25A13,PNPLA2,PTTG1,PLAC1,OSR2,DDR1,EMP2,BCAP31,SH3KBP1,IER3,MAGOHB,PDGFA,WEE1,NOV,TGFBR3,IL6ST,KLF3,DNM2,CTTN,MARCH2,LMAN1,CTDSP2,MYO5B,CPD,TMCC2,BAG4,CAPN6,PBK,ACBD3,ACO1,SLC11A2,GLO1,RAB2B,LCP1,DPYSL3,PTGS2,IDE,JAK1,ACYP1,HOXA9,BMP1,CHPT1,RECQL,LASP1,SORT1,INPPL1,PINK1,MRC2,CDKN1C,SCOC,KLHL13,MAN1A2,ERI2,RACGAP1,COL4A5,RBP7,FAM21C,FBLN1,TNFRSF19,HOXB2,SIRPA,SGPL1,ADD3,DNPEP,FUT2,CYR61,DRAM1,BRAT1,AK3,ACAD8,NTN1,SLC45A3,FAH,DUSP1,FADS2,QSOX1,PDGFC,KIF20A,NR3C1,ZC3H11A,NR4A1,LITAF,TCF7,BCL2L13,AIF1L,TP53INP2,FOS,KIF11,NUBP1,RANBP9,MAP1B,GNAS,FECH,FUCA1,PITX2,PTPRF,FNTA,DGCR2,TWSG1,FGFR2,DCUN1D1,RAB31,PLD1,ITGAV,SERPINB1,AHR,HIPK3,RAD21 |
| 6.221e-04 | -7.38 | ACTIN_FILAMENT_BASED_PROCESS | MSigDB lists | ACTIN_FILAMENT_BASED_PROCESS | 113 | 30 | 17758 | 2588 |
WASF3,PACSIN2,TAOK2,SORBS1,RHOA,NF2,SSH1,DSTN,EZR,TESK2,RACGAP1,ARHGDIB,SORBS3,MRAS,BCAR1,RASA1,RND1,ARHGEF10L,TSC1,RND3,LIMK1,DLG1,CAPG,PRKG1,ARAP1,FGD6,ARF6,SHROOM2,CCDC88A,FGD1 |
| 6.221e-04 | -7.38 | IKEDA_MIR30_TARGETS_UP | MSigDB lists | IKEDA_MIR30_TARGETS_UP | 113 | 30 | 17758 | 2588 |
SEC23A,ACVR1,PPP1R12A,CPEB4,NRBF2,CAST,MAN1A2,GALNT7,FNDC3A,KDM3A,NFIB,NFAT5,ARF4,RASA1,XPR1,IRS2,DDAH1,PI4K2B,SLC6A6,PDCD10,WDR44,DPYSL2,CSNK1G1,RAP2C,UBE2D2,UBE2J1,NCAM1,SEMA3A,CPEB2,ATP2B1 |
| 6.225e-04 | -7.38 | PID_AVB3_INTEGRIN_PATHWAY | MSigDB lists | PID_AVB3_INTEGRIN_PATHWAY | 74 | 22 | 17758 | 2588 |
COL9A3,RHOA,COL6A2,AKT1,PIK3R1,COL4A5,F11R,COL7A1,ILK,CBL,BCAR1,SDC1,COL12A1,SPP1,IGF1R,COL13A1,CSF1,COL6A1,PIK3CA,CDKN1B,ITGAV,COL16A1 |
| 6.225e-04 | -7.38 | DER_IFN_ALPHA_RESPONSE_UP | MSigDB lists | DER_IFN_ALPHA_RESPONSE_UP | 74 | 22 | 17758 | 2588 |
MX1,PLSCR1,HLA-E,TAP1,GMPR,PSME1,IFIT3,HLA-A,FAS,BTG1,ATP6V0B,PLOD2,NMI,STAT1,IRF2,TRIM21,IFIT1,HLA-C,PDXK,COL16A1,IFI6,IRF1 |
| 6.230e-04 | -7.38 | negative regulation of cell growth | biological process | GO:0030308 | 166 | 41 | 16441 | 2455 |
GAS2L1,SEMA6B,TNK1,NF2,SERPINE2,TP53,CDKN2C,NOV,SPP1,BCL6,ADAM15,CDKN1B,SEMA3G,NTN1,WNT3A,CDKN2D,OSGIN1,SEMA3B,SIRT1,SMARCA2,CDKN2AIP,ING1,PSRC1,SERTAD3,CDA,EAF2,NDRG3,CDK5R1,ULK2,JADE1,BTG1,ENPP1,PTPRJ,SERTAD2,SEMA4D,ACVRL1,CGREF1,SH3BP4,ADIPOR1,FHL1,SEMA3A |
| 6.230e-04 | -7.38 | regulation of cell-substrate adhesion | biological process | GO:0010810 | 166 | 41 | 16441 | 2455 |
NF2,ARHGEF7,SDC4,FBLN1,FAM21C,EMP2,CALR,SPP1,RAC2,ITGA3,CYR61,NPNT,PTEN,TBCD,BCL6,DNM2,ADAM15,TACSTD2,EPB41L5,CASK,MFI2,FZD4,FMN1,DMTN,PIK3R1,UTRN,EPHA1,ILK,FZD7,RASA1,ONECUT1,AP1AR,TSC1,PTPRJ,ACVRL1,CSF1,CORO1C,TRIOBP,EFNA5,ARPC2,COL16A1 |
| 6.268e-04 | -7.37 | KINESIN_MOTOR_1 | prosite domains | PS00411 | 41 | 15 | 11866 | 1802 |
KIF5B,KIF3C,KIFC2,KIF20A,KIF14,KIF13B,KIF1C,KIF23,KIF22,KIF20B,KIF13A,KIF2C,CENPE,KIF12,KIF11 |
| 6.273e-04 | -7.37 | PLTP (phospholipid transfer protein) | protein interactions | 5360 | 28 | 12 | 16036 | 2547 |
EPB41L5,NAAA,UGT8,PLAUR,IMPAD1,HLA-F,PCYOX1,GLB1L2,GALNT7,ABCA1,PGAP1,FAM69A |
| 6.273e-04 | -7.37 | ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1) | protein interactions | 50807 | 28 | 12 | 16036 | 2547 |
PACSIN2,ARAP3,REPS2,TRIP10,RAB11FIP2,RAB11FIP1,CTTN,LRRK1,PACSIN1,CBL,ARF6,SH3KBP1 |
| 6.317e-04 | -7.37 | UDP-glycosyltransferase activity | molecular function | GO:0008194 | 136 | 35 | 16491 | 2452 |
UGT8,LFNG,GALNT12,XYLT1,HEXB,MGAT5B,POMGNT1,B4GALT4,EXT2,CHPF,B4GALNT1,B3GALNT1,MGAT1,A4GALT,XYLT2,MGAT4A,ALG13,GYS1,MGAT5,GCNT1,PIGC,B3GALT6,CHSY3,B3GNT2,MGAT4B,GYLTL1B,C1GALT1C1,GALNT7,B3GALNT2,GALNT3,CSGALNACT1,B4GAT1,B4GALT3,PLOD3,POMGNT2 |
| 6.317e-04 | -7.37 | receptor signaling protein activity | molecular function | GO:0005057 | 136 | 35 | 16491 | 2452 |
ACVR1,TAOK2,PDCL,ERBB2,TGFBR1,MAPK4,ITPR2,RGS12,IRAK1,DOK4,FLRT3,MAP3K9,CDKN1B,MAPK11,MAP3K7,MAPK7,TIAM1,SYK,MAP3K3,BAG4,ACVR1C,ITPR3,MAP3K6,EGFR,PLCG1,INSR,ACVRL1,ITPR1,MAP3K11,KIAA1804,MAPK13,STK39,RGS14,MAP3K5,MAPK12 |
| 6.318e-04 | -7.37 | Rap1 signaling pathway | KEGG pathways | ko04015 | 211 | 51 | 6908 | 1076 |
ARAP3,CALM3,RASGRP3,MRAS,PDGFB,FGF19,ITGA2B,CALM2,PDGFA,SIPA1L2,RAC2,VASP,IGF1R,CDH1,CTNNB1,RALB,PRKCI,PIK3CA,MAPK11,PIK3CD,TLN2,F2R,PLCB2,TIAM1,FARP2,DOCK4,PDGFC,RHOA,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,BCAR1,EGFR,RASGRP2,GNAS,PGF,PLCG1,INSR,FGFR2,CSF1,SIPA1L1,FGF18,CTNND1,MAPK13,EFNA5,EFNA1,RGS14,RAP1GAP,MAPK12 |
| 6.318e-04 | -7.37 | Rap1 signaling pathway | KEGG pathways | hsa04015 | 211 | 51 | 6908 | 1076 |
ARAP3,CALM3,RASGRP3,MRAS,PDGFB,FGF19,ITGA2B,CALM2,PDGFA,SIPA1L2,RAC2,VASP,IGF1R,CDH1,CTNNB1,RALB,PRKCI,PIK3CA,MAPK11,PIK3CD,TLN2,F2R,PLCB2,TIAM1,FARP2,DOCK4,PDGFC,RHOA,AKT1,RAPGEF2,PIK3R1,CALM1,GRIN1,BCAR1,EGFR,RASGRP2,GNAS,PGF,PLCG1,INSR,FGFR2,CSF1,SIPA1L1,FGF18,CTNND1,MAPK13,EFNA5,EFNA1,RGS14,RAP1GAP,MAPK12 |
| 6.343e-04 | -7.36 | Collagen formation | REACTOME pathways | R-HSA-1474290 | 86 | 25 | 8202 | 1235 |
ADAMTS2,COL9A3,COL6A2,PCOLCE,P3H2,CTSB,ITGA6,COL18A1,COL4A5,COL7A1,LOXL2,COL12A1,CTSL,P4HB,COL13A1,PLOD2,CTSV,COL6A1,BMP1,ADAMTS14,PLOD3,LOXL1,COL16A1,CRTAP,TLL2 |
| 6.351e-04 | -7.36 | Tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)) | protein interactions | 24811 | 4 | 4 | 16036 | 2547 |
PDIA3,CALR,HLA-B,HLA-A |
| 6.351e-04 | -7.36 | ARHGEF10L (Rho guanine nucleotide exchange factor 10 like) | protein interactions | 55160 | 4 | 4 | 16036 | 2547 |
ANXA9,SCN2A,NR4A1,DRAP1 |
| 6.351e-04 | -7.36 | PALM2-AKAP2 (PALM2-AKAP2 readthrough) | protein interactions | 445815 | 4 | 4 | 16036 | 2547 |
PRKAR2B,TFG,PRKACA,PRKAR1A |
| 6.373e-04 | -7.36 | ACACTGG,MIR-199A,MIR-199B | MSigDB lists | ACACTGG,MIR-199A,MIR-199B | 149 | 37 | 17758 | 2588 |
SUN1,BCAM,PARP12,PPP1R2,TAB3,WDTC1,MPP5,CCNL1,ETS1,DDR1,VPS26A,FZD6,APPBP2,M6PR,CTGF,WDR44,TSPAN6,FLRT3,PDE4D,NCOA2,SIRT1,FZD4,PTPN9,SAT1,MGAT4B,RNF11,NFE2L1,CBL,PRX,HLF,RBM47,KLF12,PVRL2,CDCA7L,MAP3K11,PLXND1,RGMA |
| 6.388e-04 | -7.36 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP | 186 | 44 | 17758 | 2588 |
SUN1,PNISR,UPF3B,FAM169A,ADD1,CTSB,ETV5,APOO,CDCA3,PBX3,NANS,DUSP5,PDXDC1,RSAD1,HDAC9,RNF220,RALB,METTL7A,ATP13A3,PPP4R1,ZNF692,TSPAN13,ACAD8,TLN2,PTPRE,SGCB,BTBD3,SLC35A1,LOC81691,ALDH2,ELK3,SRSF5,FNDC3A,ALCAM,LHFPL2,GLCE,MAN2A2,ARHGAP24,TMEM164,UEVLD,OTUB2,ETAA1,SLC25A38,CHPT1 |
| 6.388e-04 | -7.36 | GSE7852_LN_VS_FAT_TCONV_UP | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_UP | 186 | 44 | 17758 | 2588 |
GAA,IBTK,ELOVL7,MCOLN3,MPP5,MGST2,SNN,SPSB1,DENND2D,KIAA1147,TFAP4,NAPG,TGFBR3,SESN3,CENPJ,MGAT4A,ATP13A3,DLG1,SGK3,TRIM21,MAP3K7,PXMP4,PIKFYVE,CASD1,MAST4,NR2C1,EPHX1,MRPS33,BCL9,USP18,STRADB,ERBB2IP,SESN1,TRUB1,DCP2,XKRX,MAMDC4,HTT,C1orf21,STAT1,ARRB1,HMGA1,CEP41,ISOC1 |
| 6.400e-04 | -7.35 | STK33_UP | MSigDB lists | STK33_UP | 268 | 59 | 17758 | 2588 |
UNKL,SPRED1,ACVR1,BMF,CPEB4,NUAK1,LFNG,RASGRP3,GDF15,EGR3,FAM198B,PHLDA1,DUSP5,ICAM1,OTUD1,SIPA1L2,NOV,BTG3,KIAA0895,KIAA1107,ITGB8,FAM20C,ZFP36,IL6ST,CD9,BCL6,DAPK1,ANKRD12,CDKN1B,SGK1,SNX16,C10orf54,NCEH1,SULF2,DUSP1,GFPT1,DOCK4,TGIF1,KIAA1841,OSTM1,COQ10B,KBTBD8,FNDC3A,RNF19B,FOS,RHOB,GLCE,FAM177A1,SCG2,RND3,LIMK1,WDR19,APPL2,SAMD8,ZBTB6,CPEB2,MAFF,ABCA1,CYBRD1 |
| 6.444e-04 | -7.35 | PARENT_MTOR_SIGNALING_UP | MSigDB lists | PARENT_MTOR_SIGNALING_UP | 545 | 107 | 17758 | 2588 |
LTBP1,TCF25,CPT2,TSC22D3,CAST,IQGAP1,DNAJC3,GMPR,SEPT4,HDAC6,ABCD4,CYHR1,ST5,SRPX,CTNNB1,TRANK1,CYP4F11,IQCE,PAPSS1,KLF3,CAPG,VAT1,ETHE1,CTH,MAP3K3,SMARCA2,VPS11,ING1,PTPN18,TCEB2,ASXL1,SYNE2,CASP9,CLSTN1,BNIP3L,SLC11A2,SLC17A5,CD40,ASB13,KCTD2,MAP3K6,RHEB,GABARAPL1,PLCG1,PEX5,SLC25A4,KLF12,ACYP1,KCNK1,MADD,STAT1,TRIM45,TRIOBP,AGFG2,CTNND1,TMEM8B,EPB41L4A,SLC27A3,F2RL1,ARNT,PRKAR1A,BIN1,RECQL,FARP1,CD63,PEX6,ATP9A,ARL4C,CYB561,SAMD9,PSIP1,FLII,ECI2,TMBIM6,ALDH7A1,HMGCL,CITED2,RPGR,TPCN1,ALDH3A2,PHKG2,TBC1D8B,OXR1,PPARA,PYGL,SCRIB,PDK3,SNTB1,RANBP9,GNAS,IL1R1,PRKAG2,KIAA0141,SLC4A4,RCBTB2,ITGA7,NAB2,ARRB1,OTUB2,CABIN1,CDK18,EFNA1,MAP3K5,SEMA3A,SLC25A38,CSRP2,DOCK9 |
| 6.464e-04 | -7.34 | Signaling Pathways in Glioblastoma | WikiPathways | WP2261 | 80 | 25 | 4455 | 729 |
AKT1,PIK3R1,TP53,ERBB2,PRKCQ,CBL,EGFR,CDKN2C,CCND1,TSC1,RB1,PLCG1,IGF1R,PTEN,FGFR2,PLCG2,E2F1,PIK3CA,CDKN1B,PIK3C2B,PIK3CD,ERBB3,GAB1,SPRY2,MSH6 |
| 6.496e-04 | -7.34 | nephron epithelium morphogenesis | biological process | GO:0072088 | 68 | 21 | 16441 | 2455 |
HES1,LGR4,FMN1,DCHS1,SOX9,GATA3,ILK,IRX3,CTNNBIP1,BMP2,FAT4,CTNNB1,NPNT,GPC3,SMO,DLG1,PKD2,TACSTD2,SOX8,OSR1,ADAMTS16 |
| 6.497e-04 | -7.34 | 4-hydroxyproline metabolic process | biological process | GO:0019471 | 12 | 7 | 16441 | 2455 |
PRODH,EGLN3,P4HB,P4HA2,ERO1A,PRDX4,EGLN1 |
| 6.497e-04 | -7.34 | ossification involved in bone maturation | biological process | GO:0043931 | 12 | 7 | 16441 | 2455 |
BMP2,PHOSPHO1,RHOA,FAT4,SEMA4D,ANO6,DCHS1 |
| 6.497e-04 | -7.34 | ureter development | biological process | GO:0072189 | 12 | 7 | 16441 | 2455 |
GATA3,OSR1,SOX8,NPHP3,RET,SOX9,TBX18 |
| 6.497e-04 | -7.34 | regulation of Rac protein signal transduction | biological process | GO:0035020 | 12 | 7 | 16441 | 2455 |
STMN3,ARHGAP24,RASGRF1,ARAP3,ARF6,SSX2IP,DNM2 |
| 6.506e-04 | -7.34 | SH3DOMAIN | prints domains | PR00452 | 83 | 23 | 4759 | 661 |
BIN1,LASP1,PACSIN2,SORBS1,ARHGEF7,SH3D19,SORBS3,YES1,TEC,BCAR1,SH3KBP1,SH3RF2,SH3D21,PLCG1,FYN,PLCG2,MAP3K9,KIAA1804,MAP3K11,OSTF1,CTTN,PACSIN1,NEB |
| 6.507e-04 | -7.34 | negative regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000134 | 101 | 28 | 16441 | 2455 |
PSMB4,PSME2,CTDSPL,PSMD7,TP53,PSMD10,PSME1,PSMA4,TP73,CCND1,JADE1,E2F7,RB1,PSMD1,PTEN,DACT1,PSMD3,PSMC2,FBXO7,BRD7,CDKN1B,KANK2,PKD2,FHL1,PSMC1,CTDSP2,PSMA5,CTDSP1 |
| 6.513e-04 | -7.34 | negative regulation of protein depolymerization | biological process | GO:1901880 | 59 | 19 | 16441 | 2455 |
GAS2L1,ADD1,CKAP2,DMTN,EPS8,AURKB,CCNB1,HDAC6,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,CAPG,TRIOBP,AURKA,TMOD2,SPTBN5,SHROOM2 |
| 6.513e-04 | -7.34 | FER (fer (fps/fes related) tyrosine kinase) | protein interactions | 2241 | 21 | 10 | 16036 | 2547 |
CTNNB1,CDH1,JAK1,CALM1,DNM2,ERBB2,CTNND1,CTTN,ERBB3,EGFR |
| 6.513e-04 | -7.34 | B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) | protein interactions | 10678 | 21 | 10 | 16036 | 2547 |
CAPN2,ADAMTS2,TMTC3,ITGA7,FAM3C,C1GALT1C1,NRG1,GALNT7,MOXD1,TUBA4A |
| 6.513e-04 | -7.34 | ITGA3 (integrin alpha 3) | protein interactions | 3675 | 21 | 10 | 16036 | 2547 |
CALR,BIN1,TIMP2,ITGA3,LGALS8,CD82,CD9,FHL2,PDIA3,FBXO6 |
| 6.561e-04 | -7.33 | MORF_DAP | MSigDB lists | MORF_DAP | 79 | 23 | 17758 | 2588 |
SYPL1,SOD1,DAP,CALM1,CALM3,ERP29,BCAP31,ARF4,VPS26A,CALM2,DDOST,PRDX3,GDE1,TMBIM6,GLB1,KPNA2,MDH1,PPP1CA,TECR,SLC35A1,TMED2,KDELR1,GPX4 |
| 6.562e-04 | -7.33 | negative regulation of catalytic activity | biological process | GO:0043086 | 815 | 155 | 16441 | 2455 |
CASP3,FAF2,PPP4R4,IBTK,DNAJC3,ARFGEF1,XIAP,F11R,PSME1,HDAC6,TP73,CDKN2C,PSMD1,CABP1,RGS3,PSMC2,DUSP10,CRY2,PLK1,PRKAR2B,PIF1,PPP1R14C,POR,NEIL1,CAMK2N2,LIMK1,PPP2R4,SERPINB6,SERPINI1,GLA,HSPB1,PSMC1,LMTK3,PPP1R2,CDKN1C,SERPINE2,PPP1R12A,UBASH3B,PSMD7,DUSP5,SH3RF2,TFAP4,RB1,TIMP1,IGF1R,FBXO7,PAK2,FNIP1,SORL1,MAPK7,PSMA5,TMED2,SOCS5,EPHA1,ILK,PSMA4,PLIN5,FAS,PRKAG2,SEMA4D,HTT,SH3BP4,CABIN1,SERPINB1,IFI6,RPS6KA3,DRD1,EGLN1,SPRED1,NF2,NQO1,RPS6KA1,IQGAP1,PSME2,CAST,PTTG1,TP53,WDTC1,SYTL2,CD46,APLP2,PPME1,FICD,CDKN1B,DAB2IP,IFIT1,DLG3,CDKN2D,TMBIM1,CHP1,SIRT1,PPIF,CAMSAP3,TIMP2,BAG4,AKT1,CDC20,COX11,PKMYT1,DUSP4,SOCS3,IRS2,PTPRJ,PPP2R5A,STK38,CORO1C,PSMD3,WWTR1,RGS14,PRKAR1A,ARFGEF3,ANXA3,SORT1,FARP1,TRAF2,SERPINB9,PSMD10,NES,PKN1,TRIB2,GSTP1,AIP,TIPRL,SH2D4A,CD109,PPP1R10,PTEN,GPC3,BMP7,CST3,TMBIM6,H2AFY,BUB1,HEXIM2,RAG1,GFI1,SPRY2,DUSP1,PSMB4,PLAUR,FURIN,COL7A1,LEPR,MAPK8IP1,CDK5RAP1,TIMP3,SERPINA1,PRDX3,SPINT2,ARRB1,SERPINB5,UBE2C,CPEB2,HIPK3,PKIA |
| 6.587e-04 | -7.33 | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | 197 | 46 | 17758 | 2588 |
LAMP1,GALK1,AASS,DNAJB2,RHBDL3,MCCC1,TP53,GATA3,SELL,PSME1,GRK6,FAM101B,PCBP1,STIM1,KCNN4,TSPAN6,ZFP36,BMP7,LMO4,FOSB,FAM102A,F2R,NR2C1,DUSP1,PGM1,UFD1L,PRSS23,TNIP1,USP18,SLC11A2,TCF7,GLO1,TNFAIP8L1,YES1,SESN1,LCP1,CMTM7,SOCS3,CD8A,SCARB2,MAP2,FAAH,NFKBIA,MAP3K5,TOB1,XDH |
| 6.587e-04 | -7.33 | HALLMARK_INFLAMMATORY_RESPONSE | MSigDB lists | HALLMARK_INFLAMMATORY_RESPONSE | 197 | 46 | 17758 | 2588 |
IL15RA,IL15,CD82,SELL,P2RX7,IL18,SLC7A2,IL18R1,TNFSF9,CHST2,ICAM1,MXD1,ITGB8,TIMP1,GPC3,CD70,PTPRE,RASGRP1,ATP2B1,LAMP3,P2RX4,CD55,RIPK2,PLAUR,PTGER4,CALCRL,EMP3,SLC11A2,CD40,IL1R1,TAPBP,SLC4A4,SEMA4D,CSF1,AXL,NFKBIA,NMI,NOD2,OSMR,IRF7,ICOSLG,FZD5,SLC31A2,ABCA1,AHR,IRF1 |
| 6.587e-04 | -7.33 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | 197 | 46 | 17758 | 2588 |
TXN,S100A11,PTTG1,GATA3,EFHD2,FAM46C,MNS1,IL18R1,FGF19,SLC35E4,HLA-A,CAPN2,DAPK2,WEE1,PCNA,FOSB,AIM1,SORL1,MDFIC,TMEM37,PIM1,CTSD,F2R,SNX10,S100A13,RPGR,S100A6,POU6F1,PLSCR1,SNTB2,S100A4,CRIP2,CAPNS1,YES1,CYFIP2,DOCK5,RNF19B,FOS,CASP4,NUCB1,ENPP1,H1F0,CHPT1,TOB1,ACOT7,XDH |
| 6.587e-04 | -7.33 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | 197 | 46 | 17758 | 2588 |
ENO2,MPZL1,AASS,PSME2,TSC22D3,GMPR,SELL,CALM3,TP53I11,SEPP1,DHRS3,S100A2,PDXDC1,PDIA4,CALM2,TYMP,ITGA3,GPC3,RRBP1,FAM102A,TRIM21,CTTN,S100A13,FAH,MX1,P2RX4,AMOTL2,COL6A2,SLC39A8,PLAUR,SAT1,CALM1,EMP3,FXR2,OPTN,KDSR,SERPINA1,H1F0,ACVRL1,PLK2,ARAP1,SSNA1,GDF11,LTA4H,IFI6,MAFF |
| 6.587e-04 | -7.33 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | 197 | 46 | 17758 | 2588 |
CASP3,ARHGEF3,PARP12,SERPINE2,SERPINB9,PTTG1,TESK2,EFHD2,P2RX7,EGR3,PLA2G16,PHLDA1,SNX9,DUSP5,SYTL2,FAM111A,WEE1,NOV,MGAT4A,IL6ST,TPST1,TSPAN13,PACSIN1,IL10RB,RASGRP1,MSH6,ARAP2,ERMP1,CENPA,CDC20,MBNL3,RAB3IP,CDK1,CMTM7,CD83,KLHL2,FYN,PRKAG2,PTER,ITPR1,CAB39,KPNA2,PLXND1,TRAF5,TBC1D4,ISOC1 |
| 6.620e-04 | -7.32 | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP | MSigDB lists | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP | 47 | 16 | 17758 | 2588 |
QSOX1,SELL,AKR1E2,SLC20A1,TRIM68,NFIX,NAT1,IL6ST,SIVA1,SMO,CSGALNACT1,PKD2,HOOK1,CSRP2,FAM134B,FAM69A |
| 6.620e-04 | -7.32 | MODULE_312 | MSigDB lists | MODULE_312 | 47 | 16 | 17758 | 2588 |
PLK1,MX1,LGALS3,DNAJC3,CDC20,BIK,MYBL2,BNIP3L,BCL2L1,CCNB1,STK17B,IER3,FAS,BCAR3,PCNA,E2F1 |
| 6.658e-04 | -7.31 | vpr (p15) | protein interactions | 155807 | 562 | 118 | 16036 | 2547 |
LAMP1,CASP3,FOXM1,CUL4B,TP53,CCNO,CUL1,FTH1,BCL2L1,ISOC2,CCNB1,PRKACA,ECI1,RAD23A,WEE1,CDH1,P4HB,CAPG,TUBG1,VAT1,IFIT1,ACSL4,ETHE1,SCARA3,NFKB2,HSPA2,APOBEC3G,PLK1,MX1,CENPA,AKT1,AGPS,ACBD3,CASP9,EZR,ARHGDIB,PRKAR2B,AURKB,RAD17,CD40,SLC25A5,CDC25C,CDK1,PTGS2,PPP2R5A,SLC25A4,CCNB3,DNM1L,PPP2R4,STAT1,HDAC1,MAPK13,KPNA2,IRF7,SGOL1,HSPB1,PPP2R5D,PRKAR1A,PCSK5,DDX58,PRKAA2,GGA1,TAB3,ITGA6,DNAJB2,CTSB,PRKAA1,MTL5,PSMD7,PDIA3,ASAH1,CTSZ,HDGFRP2,GSTP1,HLA-A,LMNA,PPP2R3A,GNS,CALR,TIMP1,RRBP1,BAX,PRKCI,ACTA2,TAGLN2,HLA-C,MAP3K7,CTSD,ULBP2,NUP85,DUSP1,ACBD5,DDB2,RHOA,NR3C1,IFITM3,NR4A1,PKM,IFIT3,FOS,SMN1,RHOB,CD83,FAS,MAPKAPK2,HLA-B,SCARB2,CASP7,PRKAG2,NFKBIA,UBE2D2,DYSF,CTSA,CCNB2,CBX5,AHR,CD33,RAD21 |
| 6.660e-04 | -7.31 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN | 181 | 43 | 17758 | 2588 |
COL9A3,ST14,CKAP2,INPP5D,ADO,PDCL,SELL,MRAS,EGR3,C11orf95,PARM1,CDK14,CCNA2,PPP1R10,ZFP36,IQCE,BHLHE41,FOSB,KIAA0319,SGK1,OSTF1,PIM1,PTPRE,KIAA0040,NRBF2,ASPM,CDC20,DBR1,MGAM,CR2,CYP4F3,SOCS3,DHX32,OSBPL2,PTGS2,SEMA4D,ZFP30,AURKA,F2RL1,CCNB2,ABCA1,EHD1,EGLN1 |
| 6.660e-04 | -7.31 | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP | 181 | 43 | 17758 | 2588 |
GAS2L1,SUN1,CCNC,CCDC109B,DGKA,MORC4,CALM3,PHF1,AIP,CALM2,RPS6KA2,ARTN,GNB5,LYPD3,MCF2L,FABP6,PASK,WWP1,EPHB4,LOXL1,SMYD5,MAST4,SEMA3B,FBLN5,MPP1,CALM1,STMN3,MEST,PRKRA,STK17B,PLEKHB1,ATP1A1,TJP3,PAFAH1B3,CSGALNACT1,INPP4B,NR4A2,HMGA1,RGS14,TBC1D4,HSPB1,PKIA,FAM134B |
| 6.671e-04 | -7.31 | KEGG_GLIOMA | MSigDB lists | KEGG_GLIOMA | 65 | 20 | 17758 | 2588 |
AKT1,CALM1,PIK3R1,TP53,CALM3,PDGFB,EGFR,PDGFA,CALM2,CCND1,PLCG1,RB1,IGF1R,PTEN,SHC3,PLCG2,E2F1,PIK3CA,PIK3CD,CAMK2G |
| 6.671e-04 | -7.31 | TENEDINI_MEGAKARYOCYTE_MARKERS | MSigDB lists | TENEDINI_MEGAKARYOCYTE_MARKERS | 65 | 20 | 17758 | 2588 |
CCNE2,CASP3,PDGFC,CASP9,CCNB1,PDGFB,FOS,CDK1,RASA1,ITGA2B,MECOM,RASGRP2,IL1R1,PDGFA,GATA2,STAT1,CD9,CDKN1B,PIK3C2B,JARID2 |
| 6.691e-04 | -7.31 | T cell receptor signaling pathway | biological process | GO:0050852 | 146 | 37 | 16441 | 2455 |
THEMIS2,INPP5D,PSME2,PSMD7,BTN3A1,GATA3,CUL1,PSMD10,PSME1,TEC,CACNB4,VASP,PSMD1,PTEN,PSMC2,PAK2,PLCG2,PIK3CA,PIK3CD,PDE4D,MAP3K7,PSMA5,PSMB4,RIPK2,PIK3R1,PRKCQ,BCAR1,PSMA4,TXK,BCL10,PLCG1,PTPRJ,FYN,PSMD3,NFKBIA,UBE2D2,PSMC1 |
| 6.717e-04 | -7.31 | GCM_PTK2 | MSigDB lists | GCM_PTK2 | 139 | 35 | 17758 | 2588 |
TMEM184B,GPR107,BACE1,C1orf198,TEX2,NCS1,APPBP2,CCDC92,NAPG,SESN3,ANKS1B,FRYL,DDHD2,DLG1,CCDC82,NPTN,BTBD3,CAMK2G,CCDC88A,CLCN3,TRIM8,ZNF84,KIAA1109,DNAJB14,BBS2,NDRG3,TP53INP2,PLEKHB1,ULK2,GPRC5B,PHLPP2,TMEM30A,TMOD2,NIPA1,DOCK9 |
| 6.729e-04 | -7.30 | MARKEY_RB1_ACUTE_LOF_UP | MSigDB lists | MARKEY_RB1_ACUTE_LOF_UP | 208 | 48 | 17758 | 2588 |
GRN,AGRN,PSME2,IQGAP1,NDRG1,CTSB,SERPINB9,TAP1,SOD2,NDRG2,CTSZ,CRABP2,TNFSF9,LGALS3BP,SGPL1,RAC2,SP100,PFKL,FAM13B,IFIT1,ACSL4,LGMN,SGCB,USP18,PLEKHO1,SAT1,UBE2A,BNIP3L,FNDC3A,IFIT3,CASP4,LCP1,SOCS3,TAPBP,MID1IP1,STAT1,SH3BGRL2,IRF7,CMPK2,IFIH1,ARNT,HIPK3,ABCA1,FAM134B,PCSK5,ABCG1,EGLN1,XDH |
| 6.737e-04 | -7.30 | BARRIER_COLON_CANCER_RECURRENCE_DN | MSigDB lists | BARRIER_COLON_CANCER_RECURRENCE_DN | 19 | 9 | 17758 | 2588 |
NUCB1,PFKL,AES,CTSA,HLA-C,ASB13,CITED2,NDFIP1,TSPAN7 |
| 6.737e-04 | -7.30 | CYTOKINESIS | MSigDB lists | CYTOKINESIS | 19 | 9 | 17758 | 2588 |
SEPT6,PRC1,DIAPH2,NUSAP1,RACGAP1,CNTROB,SEPT4,ANLN,RASA1 |
| 6.737e-04 | -7.30 | REGULATION_OF_JNK_ACTIVITY | MSigDB lists | REGULATION_OF_JNK_ACTIVITY | 19 | 9 | 17758 | 2588 |
KIAA1804,MAP3K11,MAP3K9,MDFIC,PKN1,MAP3K5,MAP3K6,HIPK3,MDFI |
| 6.737e-04 | -7.30 | PID_EPHA2_FWD_PATHWAY | MSigDB lists | PID_EPHA2_FWD_PATHWAY | 19 | 9 | 17758 | 2588 |
INPPL1,RHOA,PIK3R1,PIK3CA,EFNA1,CBL,TIAM1,BCAR1,ARHGAP35 |
| 6.737e-04 | -7.30 | HU_ANGIOGENESIS_UP | MSigDB lists | HU_ANGIOGENESIS_UP | 19 | 9 | 17758 | 2588 |
NAPG,PRODH,RND3,SIPA1L1,PIK3R1,COL7A1,NRGN,FOS,FAH |
| 6.737e-04 | -7.30 | DELLA_RESPONSE_TO_TSA_AND_BUTYRATE | MSigDB lists | DELLA_RESPONSE_TO_TSA_AND_BUTYRATE | 19 | 9 | 17758 | 2588 |
RHOA,GATA2,NR4A1,CDC20,HSPB1,DDR1,POR,TOB1,ICAM1 |
| 6.769e-04 | -7.30 | site of polarized growth | cellular component | GO:0030427 | 133 | 34 | 17570 | 2579 |
ARHGEF7,IQGAP1,EPS8,EPHA4,CALM3,NDRG2,CALM2,ITGA3,FRY,SNX18,CDKL5,DPYSL2,FRYL,FLRT3,EXOC8,DNM2,MYH14,CTTN,DLG3,MYO5A,RASGRF1,ORAI2,TIMP2,CALM1,STMN3,KIF20B,CDK5R1,STX3,DPYSL3,TSC1,TMOD2,L1CAM,COBL,NGEF |
| 6.819e-04 | -7.29 | REGULATION_OF_SIGNAL_TRANSDUCTION | MSigDB lists | REGULATION_OF_SIGNAL_TRANSDUCTION | 219 | 50 | 17758 | 2588 |
SIGIRR,ACVR1,TAOK2,ARAP3,NF2,CDKN1C,RALBP1,RGS20,NOTCH2,GRK6,SLC20A1,RGS12,CARD8,PTEN,TSPAN6,RGS3,IL31RA,ZDHHC13,SLC44A2,TAX1BP3,MDFIC,RGS5,TFG,CITED2,F2R,EEF1D,MDFI,MAP3K3,CDKN2AIP,RHOA,CXXC5,RIPK2,LITAF,CD40,MAPK8IP1,BCL10,TSC1,RGS9,PLK2,SECTM1,ARAP1,NOD2,CANT1,FGD6,ARF6,RGS14,TRAF5,NDFIP1,DMPK,FGD1 |
| 6.845e-04 | -7.29 | - | gene3d domains | 3.40.850.10 | 44 | 16 | 9988 | 1574 |
KIF3C,KIFC2,KIF20A,KIF1C,KIF23,KIF20B,KIF13A,KIF2C,KIF11,KIF26A,KIF5B,KIF13B,KIF14,KIF22,CENPE,KIF12 |
| 6.870e-04 | -7.28 | WWTAAGGC_UNKNOWN | MSigDB lists | WWTAAGGC_UNKNOWN | 134 | 34 | 17758 | 2588 |
MYL9,KLF2,SLC2A4,SORBS1,SLC41A1,KLC2,ETV5,GRK6,SDC1,GSTP1,FGF19,DUSP5,HDAC9,VASP,SESN3,IRAK1,SLC16A6,PDE4D,NCAM1,ETHE1,RBMS2,SMARCA2,TFAP2C,PPP1R14C,NFIB,ANKRD10,PI4K2B,MAP2,WIPI1,MYLK,SPAG7,ARF6,SHOX2,DMPK |
| 6.870e-04 | -7.28 | JOHNSTONE_PARVB_TARGETS_2_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_UP | 134 | 34 | 17758 | 2588 |
IGFBP6,S100A11,TP53,CALM3,BCL2L1,PKN1,CMTM6,HLA-A,CORO1B,CALM2,CALR,ZYX,APLP2,ALDH1A3,FXYD5,AKR1B1,IFIT1,C10orf54,CITED2,EPHX1,DCAF6,CALM1,FURIN,AIF1L,IFIT3,IRX3,MDK,HLA-B,AGPAT2,H1F0,PVRL2,PPP2R4,MAMDC2,DMPK |
| 6.870e-04 | -7.28 | RUIZ_TNC_TARGETS_DN | MSigDB lists | RUIZ_TNC_TARGETS_DN | 134 | 34 | 17758 | 2588 |
CCNE2,HJURP,SPC25,SERPINE2,FOXM1,TUBB4B,RGS20,KIF2C,BARD1,FANCI,FAM111A,CCNA2,TNFRSF12A,USP1,MYBL1,CKS2,ZWINT,PBK,FHL2,AURKB,MEST,CDK1,EGFR,NMT2,PRIM1,PTPRF,DDAH1,E2F1,SH3BP4,NRG1,NCAPG2,UBE2C,E2F8,MELK |
| 6.879e-04 | -7.28 | lower_third | COSMIC cancer mutations | lower_third | 8323 | 1286 | 17775 | 2585 |
FAM160B1,IBTK,GRIK2,SLC25A13,PNPLA2,HEXB,RET,TRAPPC8,BAIAP3,SNX9,LTBP3,GRM5,NAPG,MUC4,ATP13A3,DNM2,CLDN4,RNF26,WBP4,TIAM1,IL10RB,CPE,TIPARP,MGAT5,NEK4,CDA,KDELR3,TMEM151A,PRKAR2B,RNF19B,GINS4,PIAS3,ENPP1,C17orf51,ATP7B,CELF5,FAM114A1,NOD2,ITPKA,NXT2,SCN5A,ITGA6,TTYH3,MARCH8,FLII,RAC2,SH3D21,ZCCHC17,FRY,MEGF8,RIMS3,FLRT3,FBXO7,PCYOX1,SLAIN2,CADPS2,USP38,ALPK1,PANX2,CNGA1,MAPK7,ZMYM1,MYLIP,DGKG,NUP85,TTLL1,HPS3,SHARPIN,FHL2,NPHP3,GOLT1A,DPYSL4,PCTP,C11orf45,IL1R1,CACHD1,SLC4A4,ETS2,CLMN,OSCP1,GDF11,TMEM159,TMEM173,RUSC1,ADAMTS16,DOCK9,NQO1,LFNG,RHBDL3,GRK6,FAM91A1,RCN1,RBM23,MUC16,ST5,XYLT2,ENPP5,RASGEF1A,ZNF365,MYT1,TMCC2,TMEM200B,SNX8,COL6A2,ERMP1,C6orf1,RIPK2,AGPS,SEPT6,SAT1,VPS4B,SYP,TANC1,GIGYF1,CCNB3,SHROOM3,CORO1C,AXL,PNPLA6,DMWD,SLC25A30,ISOC1,MZT1,HSP90B1,FAM189A2,CKAP2,CCM2,OSGIN2,ZNF219,IFT27,NFAT5,ZFX,FUT2,IGSF9,KNDC1,GPC3,TUBGCP6,BAX,RAG1,CASD1,MED22,PARP9,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,NUB1,CXorf57,AK4,C4orf27,RPL12,PROM1,RAB11FIP2,SYT7,PPM1H,ITGAV,ACOT7,PHC1,TLL2,TMEM131,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,PHOSPHO1,DNAJB11,TEX2,GALM,ITPR2,SPTB,FANCI,TFAP2E,PLS3,SUSD2,CPNE2,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,IL6ST,PAPSS1,SLC44A1,ABCA2,SMAGP,PLK1,THRB,PTPN18,MARK1,CELSR2,STAU2,CBX6,CR2,CCBL2,CKAP2L,SESN1,DZIP1L,KDM4D,TRIM9,TNS4,PLEKHG6,HS6ST1,TRAM2,KLF12,ZNF367,ARRDC1,KPNA2,MYL12B,TC2N,RRAGD,PARP12,RUNX2,USH1C,FXYD3,RASA2,PSMD7,PDCL,ADCK5,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,PIM1,FAR2,NTN1,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,ZSCAN12,BCL2L13,PRX,FOXD2,FA2H,COL13A1,KBTBD2,PHLPP2,OTUD6B,SLC2A6,ZDBF2,PLD1,AKIP1,SEMA3A,CDAN1,CCNB2,USP43,HOXB7,TP53,RHPN2,PCBP1,STIL,SYTL2,TTC21B,WDR44,TACC2,LMO4,PPME1,BCL6,PLK4,GLB1L2,ESPN,NOTCH3,OAS3,CLCN3,ERLEC1,AKT1,PTGER4,ATP13A2,PTGS2,ZNF628,IDE,PTPRJ,PAFAH1B3,RBL1,MAOA,EFNA5,IRF7,ST3GAL1,FAM134B,ZMAT1,CMAS,DYRK3,CDH22,TAB3,CTSB,GNAL,ERCC6L,GDF15,AIP,VPS26A,NRP2,FZD6,SH2D4A,FOXP2,ALPP,GTF2F2,FAM63A,IL17RA,TSPAN13,SYK,ATP2B1,GCNT1,LRRC24,FBLN5,RHOA,GUSB,PRICKLE1,DPP9,COL7A1,TXNDC11,USP6,DDX23,CNOT2,SCG2,E2F1,SH3BGRL2,ICOSLG,HIPK3,ARHGEF9,ZBTB33,ARHGEF4,GOLGB1,FAM171B,LAMP1,PNISR,LGR4,HSPG2,SSH1,C1orf198,PSME1,SEPT4,OAT,PJA2,PICK1,SLC9A7,OSBPL3,FOSB,SERINC2,POLL,PIK3CA,KCNS3,SNX16,HYLS1,METAP2,SPATA18,CDYL,KIF13A,LDB2,POR,RAB2B,SH2D3C,LRIG1,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,CCDC97,SEMA6B,RECQL,MRC2,TBC1D1,TXNDC9,APBA1,PDXDC1,PSIP1,SH3RF2,MESDC2,C9orf69,DOPEY2,RALGPS2,BHLHE41,AIM1,DAPK1,PRKG1,OSTF1,CACNA1D,ZNF117,GFPT1,SPATA20,GCC2,KCNJ12,PRSS23,CEP89,DCHS1,WHSC1,ANTXR1,PDE11A,MMP15,SLCO4A1,PLEKHH2,TJP3,PIAS2,MPP2,ARAP1,AGBL5,CABIN1,SAMD8,ZBTB34,PER3,IFIH1,SPRED1,KIF3C,TCTN2,CAPN12,REPS2,DLGAP5,ST14,THRA,NDRG1,RALBP1,CERCAM,ATP2C2,FLT3,ZFYVE9,CD46,ACAP2,TRANK1,EPHB4,RNASEH2A,PDE4D,OSBPL7,NAGA,DOCK4,COG2,PANK1,CLSTN1,UTRN,KIF1C,PKMYT1,PYGO1,CBL,B3GALNT2,ITPR3,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,POPDC3,ACAD10,TSPAN18,ZNF704,SLC27A3,COBL,DEPDC1,HAPLN3,SLC41A1,CENPI,EPS8,CBLL1,HERC5,PBX3,NES,PLD2,DNAH3,CKAP5,SCML1,WWP2,E2F7,RNF128,FUT8,FJX1,ERBB3,SLC16A5,MSH6,FARP2,TGIF1,ZWINT,ARHGEF28,LONRF3,PAPD7,ZKSCAN2,FBXO9,DIAPH2,GRTP1,AIF1L,FOS,ARSK,KIF11,CDK5RAP1,DGCR2,RIN3,TBX18,ABCB1,WDR91,WDR62,ESPL1,RGMA,UGT8,UBE2Q1,VARS2,PLAC1,MPP5,ZFYVE16,SIPA1L2,CASC4,ARHGEF37,ANKFN1,CEP78,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,LAMP3,CYP1B1,ASXL1,ITCH,RGAG1,ARHGDIB,MAN2A2,MADD,ZNF165,SP6,RBM43,PCSK5,ARAP3,BVES,ETV5,ABCG2,CALM3,PM20D2,FAM81A,ADAMTSL4,CES2,FAM20C,OCRL,COL6A1,PRKCI,LIMCH1,C10orf54,ETV7,SLC12A2,CCDC88A,SNED1,SNX7,MDFI,PODXL2,VWA1,PDE5A,KIAA1109,HEATR5A,NUBP1,RANBP9,SOX13,INSR,UAP1,TMEM30A,SHROOM2,JAK3,COL16A1,RARG,AFAP1,DRD1,CCNE2,NCKAP5,PAX6,SORBS1,PDIA5,COL18A1,IL27RA,MRAS,PHLDA1,EXT2,KCTD9,MXD1,ZNF687,KIF14,REEP1,ZBTB49,EPB41L4B,ECE1,ETHE1,SOAT1,PTPRU,TMTC2,CDC25C,CASP4,ARHGAP35,HSF4,ALDH5A1,STAT6,PTBP3,TLE1,RCAN2,SPTBN5,MAD2L1BP,ABCA1,GCLM,ARHGEF11,ARHGEF7,SH3D19,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,RBP7,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,TOP2A,TAF1B,LLGL2,A4GALT,BMP7,TOX2,RRBP1,CLIP2,SLC35A1,MYO5A,PGM1,PHF20L1,DCAF6,RC3H2,RUNX3,LEPR,LEMD2,ARHGAP24,CD8A,CASP7,TRIM69,FIBCD1,ARRB1,UACA,GRAMD1C,ZMIZ1,AHR,RAB3IL1,ABCG1,CD33,NGEF,DOC2A,ACACB,AASS,TRIM5,CACNA2D2,DHX8,FAM102B,LGI3,CNTROB,CA8,KIF26A,BARD1,EPDR1,DAPK2,TP73,ZYX,PSMD1,RGS12,DNAH6,PPP1R16A,SLC46A1,KLF3,ALDH1A3,SEMA3G,ODF2L,ERAP2,TUBA4A,NWD1,SMARCA2,TNIP1,SH3BGRL,MTRF1L,LOXL2,PPP1R14C,MYOM1,COL12A1,SLC44A3,GRID2IP,WDR11,DNM1L,MYLK,AGFG2,ARF6,LSM14B,FAM169A,NFKBIE,TMTC3,SOX9,SLC36A4,ZNRF3,MERTK,GNS,DNPEP,ZIC5,FAM13B,STT3B,NCAM1,NAGPA,SLC37A1,KIF20A,SALL4,STAT4,CALCRL,PLS1,MEST,DCP2,RHOB,DHX32,STK17A,PTPRF,NCOA3,HTT,SETD3,TEX30,ITPR1,DYSF,AURKA,OSMR,ALG2,ARPC2,DRP2,NDE1,ZNF502,SERPINB1,XDH,EGLN1,FAM131C,ACTR8,RGS20,WDTC1,PKP2,TESK2,NUF2,PRSS22,PRKACA,APC2,TNFSF9,ZNF385B,UHRF1BP1L,CCND1,RNF220,SP100,DACT1,ACSL4,SCN3A,RNF169,ENPP4,SSH3,CAMSAP3,PLEKHO1,SYNE2,NUSAP1,CDCA2,STX10,TTC12,SLC9A6,WWTR1,INPP4B,PLEKHG1,PDXK,RGS14,TTC8,FARP1,TAOK2,TNRC6C,NKX3-1,PARP14,MAN1A2,PDIA3,ANO9,PKN1,ETS1,KCNC4,PDIA4,DTX3L,CAPN2,ANK1,ADD3,SLC27A6,FAM160A2,ARSG,CTSC,ANKS1B,CALD1,ADAM15,ECI2,TMBIM6,WWP1,SGCB,TPCN1,TMX1,HCN3,LCA5,FMN1,FAM160A1,RAPGEF2,EIF5A2,GRIN1,DBR1,PLEKHA7,FAM109A,SNTB1,CRISPLD2,ABLIM2,TXK,DCAF10,GALNT3,ACVRL1,ATXN7L3,ARFGAP3,CENPE,NUP37,SHOX2,FOXA1,TRIM2,AGRN,GNPDA1,CUL4B,EPHA4,MCCC1,NDC80,PDGFB,LMAN2L,MKRN3,DUSP10,TNFRSF18,TLN2,ANO4,TRAM1,MYBL1,NEB,DDX59,ZNF462,PCGF5,EZR,ESYT1,IDH1,ZBTB7B,VCP,OPTN,DPYSL3,MFAP3L,MSL1,CDCA4,MAP2,P4HA2,RAB11FIP1,PIK3C2B,PIEZO1,GLCCI1,PRKAA2,UBASH3B,RACGAP1,CNTNAP2,DOCK11,PGAP1,SSX2IP,CORO1B,RB1,DAZAP1,VASP,IGF1R,SPIN4,EXOC8,PLCB2,ABCC1,CHSY3,SPATA13,EIF2AK1,UNC45B,G2E3,SMN1,COQ10A,PVRL2,CSF1,MFSD2A,ITGA7,PRPS2,LTBP2,RNF146,UGP2,XYLT1,DGKA,ZNF28,ERBB2,CCDC68,CCNL1,SLC7A2,SDF4,PER2,CDK14,EFR3A,PLCG2,N4BP3,SRR,SCN2A,FAR1,GM2A,CTH,CPD,SIRT1,TMTC1,S100A4,CDC20,DUOX1,ATP1A1,ADAMTS14,RPL22,LTA4H,AIFM3,NDST3,ZNF701,ZC3HC1,MAN2B2,COL9A3,PACSIN2,TRAPPC10,RUSC2,GNE,GABRG2,NKRF,JAG2,CHAC2,DSE,CRABP2,SIRPA,PPP2R3A,SLC9A2,GBX2,CEP97,MAGEE1,SLC35B4,BUB1,SLC45A3,FAH,IGDCC4,DLGAP1,HMMR,IFITM3,NR3C1,AMFR,PPARA,PELI3,AKAP3,NPDC1,BSDC1,PRDX4,FUCA1,FAT4,ZNF214,TMC5,NMI,NETO2,FAM117A,CLIP4,PPP2R3C,PKD2,TBC1D4,DIS3L,SUN1,GAA,PPP4R4,FAM129B,ATP8A1,KLC2,GATA3,CCNB1,FAM101B,SLC20A1,ELMOD2,CHST2,NCS1,SESN3,CTGF,PRICKLE3,RGS3,STEAP2,AOX1,ATRNL1,IQCD,PACSIN1,XKR8,ORAI2,TMEM68,HSPA12A,MGAM,TNS1,PIF1,ULK2,AHRR,SFXN1,KDSR,SLC25A4,PLK2,GNPTAB,TBX1,NKD1,DHTKD1,EIF4EBP2,TANC2,TRAF5,LZTS1,DLAT,DDX58,CDK17,INPPL1,FRMD4A,DGKQ,KIF23,C6orf106,ISYNA1,NOTCH2,PRRG4,MECOM,ITGA3,PIK3AP1,SLC16A6,NECAB3,BDH1,RUNDC3B,SORL1,CTSD,TSPAN33,RIMS2,FAM69A,IGSF3,DNAI1,EPB41L5,B3GNT7,PMPCB,KIAA1841,MFI2,TBC1D8B,ANO6,KDM3A,FBXO10,GLT8D2,RASA1,DGKH,GABRD,PRKAG2,ISM1,SLC4A3,PCDH19,EFNA1,MAP3K5,NRBP1,PKD1L2,FRMPD3,PLA2G4A,SLC2A4,NLRX1,S100A11,TRIP10,CAST,IQGAP1,BROX,IRX4,KCTD12,RNF182,CD274,MNS1,GNB2,APLP2,FAM46A,TNPO2,CNNM4,DAB2IP,IFIT1,LGMN,NR2C1,GPX4,TBC1D10B,MYO5B,SLC5A11,CDKN2AIP,CAPN6,TMEM43,TEP1,PRKCQ,BCL7B,C15orf39,CMTM7,NIN,ZNF641,FYN,JAK1,PPP2R5A,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,ZC3H12B,HS3ST3B1,MLKL,NR3C2,DENND5B,WASF3,ARHGEF3,PCOLCE,ANKRD13D,SLC16A14,SEPP1,PNPLA5,SIX4,LGALS3BP,AKIRIN1,FAM111A,PHF7,OXCT1,PTEN,MGAT1,CENPJ,PRC1,SGK3,ATP8B1,MAP3K7,GFI1,SPRY2,OSGIN1,NCOA2,SMC4,RASGRF1,CASK,ERMAP,MPP1,TEF,PARP4,GPLD1,RGS9,MAMDC4,PRDX3,SLC25A40,PGM2L1,NCAPG2,CPEB2,USP16,JARID2,ESYT2,EXPH5,LTBP1,CASP3,TMEM184B,CAMKK1,TAF6L,DNER,CACNB4,KREMEN1,TMC1,PTCHD4,CHPF,ARHGEF10L,LRRC6,GRHL1,ZCCHC12,DPYSL2,CAPG,DLG1,ANKRD12,POF1B,SUN3,ARNT2,SLC39A10,TECR,PTPRE,TDP1,SYNE3,ROR1,PTGFRN,TCN2,LRRC42,ZNF114,ARHGEF19,NEIL1,UEVLD,IARS2,TRIM45,APBA2,RAP1GAP,MIIP,PPP2R5D,CPPED1,GRN,PEX6,ASL,ATP6V1E2,PHLPP1,LYSMD4,ZNF432,CA2,RFX5,KNTC1,KDELR1,PARD3B,OXR1,GYLTL1B,BTN3A2,AMDHD1,EGFR,MUM1L1,GNAS,XKRX,TSC1,ONECUT1,SLC6A6,CGREF1,RHOBTB2,ALPK3,KLF7,FBXW5,PROM2,SLC25A24,ZSWIM5,FAM92A1,SLC2A8,ABCG4,TDRKH,MICALL2,ARHGEF16,SS18,KCTD15,FRYL,SMO,TWIST1,APIP,PDIA6,HSPA2,ZNF525,KREMEN2,ERBB2IP,SNAPC2,DOCK5,BHLHB9,OVOL1,PLXND1,CYP2U1,AKNA,SGOL1,PPP2R2D,LIFR,SORT1,FRMD6,MIER3,NOTUM,POMGNT1,SAC3D1,IRF2BPL,MDM1,ADORA1,MLPH,KIAA0319,TRIM3,IQGAP3,FAM219A,SUN2,ADAM17,ASPM,NR4A1,MBNL3,LRRC66,POLD3,SPAG1,MAP1B,KLHL2,DHRS2,HOXB13,SOX8,ATP6V1C1,GEM,LRRC57,ZNF596,SNPH |
| 6.881e-04 | -7.28 | - | gene3d domains | 1.10.472.10 | 40 | 15 | 9988 | 1574 |
CCNE2,CCNC,CCNI,CCND1,RB1,CCNA2,CCNB3,RBL1,CCNO,CCNJL,CCNL1,CCNF,CCNB1,CCNB2,CDK5R1 |
| 6.881e-04 | -7.28 | extracellular matrix disassembly | biological process | GO:0022617 | 121 | 32 | 16441 | 2455 |
COL9A3,CASP3,HSPG2,CTSB,FLOT1,COL18A1,COL4A5,SPP1,CDH1,TIMP1,COL6A1,CAPG,EXOC8,ADAM15,CTSD,COL6A2,ADAM17,TIMP2,FURIN,COL7A1,CAPNS1,LCP1,COL12A1,MMP15,CTSL,COL13A1,CTSV,BMP1,KLK7,COL16A1,CAPN1,TLL2 |
| 6.881e-04 | -7.28 | cellular response to hypoxia | biological process | GO:0071456 | 121 | 32 | 16441 | 2455 |
PINK1,NKX3-1,SLC2A4,EPAS1,NDRG1,PRKAA1,TP53,CCNB1,ICAM1,LMNA,IRAK1,P4HB,PTEN,BMP7,VASN,TWIST1,CITED2,EGLN3,HP1BP3,SIRT1,AKT1,TCEB2,RGCC,SLC11A2,PDK3,PTGS2,UBE2D2,E2F1,ARNT,CPEB2,EGLN1,DRD1 |
| 6.888e-04 | -7.28 | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_UP | 192 | 45 | 17758 | 2588 |
CMAS,ST13,GCAT,JKAMP,CPT2,DAP,PTTG1,ARL4C,DGKA,UBE2Z,RACGAP1,ISYNA1,ETS1,REPS1,CORO1B,RABGGTA,ATP6V0B,ENTPD4,PHTF1,ABCA2,H2AFY,IL17RA,AK3,PIK3CD,CTSD,PDIA6,CDKN2D,TIAM1,PPIF,PCGF5,MBP,SEPT6,FHL2,BNIP3L,ARFRP1,RAD17,BLVRA,C18orf8,CMTM7,SWAP70,STK38,DBI,FAM117A,SSNA1,CTSA |
| 6.888e-04 | -7.28 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | 192 | 45 | 17758 | 2588 |
SLC35D2,LGALS3,ASAH1,EFHD2,NDRG2,KCTD12,IL18,DHRS3,SIRPA,LMNA,APLP2,TIMP1,CST3,AIM1,BCL6,AKR1B1,SGK1,CDKN1B,MTMR11,OAS3,ALDH3A2,ATP2B1,TUBA4A,PPIF,IFITM3,S100A4,SAT1,PTGER4,EMP3,ATP1B1,DOCK5,FYN,SERPINA1,RCBTB2,PRCP,LIMK1,RIN3,RAB31,TCEAL4,ARRB1,SERPINB6,KLF11,EIF4EBP2,AHR,CD33 |
| 6.888e-04 | -7.28 | GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP | 192 | 45 | 17758 | 2588 |
SLC25A24,ARMCX3,JKAMP,IQGAP1,SOX9,ABCG4,PDCL,PDIA3,PHOSPHO1,COL4A5,NOTUM,CA8,DDR1,EMP2,SRPX2,BCAP31,ANO1,ICAM1,PER2,PDGFA,METTL7A,P4HB,PCYOX1,TPST1,CCDC82,STEAP3,EPHX1,MX1,RHOA,FBLN5,PQLC3,PNKD,ALCAM,PRIM1,SLC44A3,HLF,POPDC3,NR1D2,COL13A1,ERAP1,LRRK1,PDXK,PER3,NCAPG2,ABCG1 |
| 6.888e-04 | -7.28 | GSE3982_CTRL_VS_LPS_48H_DC_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_48H_DC_DN | 192 | 45 | 17758 | 2588 |
PARP12,LRRFIP2,NQO1,PSME2,HERC5,LGALS3BP,DRAM1,BRD7,TWIST1,RFX5,IFIT1,PIM1,CTTN,TFG,APOBEC3G,FAM69A,ABCC1,DUSP1,LAMP3,MX1,PPIF,SOD1,ALDH2,PODXL2,TNIP1,IFITM3,PLAUR,COQ10B,PRKAR2B,RUNX3,IFIT3,RNF19B,FANCE,SPTLC2,C18orf8,CYB5A,CRISPLD2,JAK1,SERPINA1,RND3,CSF1,NFKBIA,IRF7,ARSB,IFI6 |
| 6.888e-04 | -7.28 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | 192 | 45 | 17758 | 2588 |
LASP1,ARHGEF3,ADD1,ENO2,ARHGEF11,LFNG,SLC2A8,RASA2,MCTP2,MCOLN3,TAP1,NES,NUCB2,HERC6,SLC20A1,ANO1,NFAT5,MXD1,FOXP2,DOPEY2,RAC2,SESN3,SH3BP1,DOK4,IQCE,XYLT2,TMEM62,MTMR10,POLL,PIK3CD,FAH,PAQR7,UTRN,ARHGDIB,ASB13,PLCG1,RTN4RL1,ATXN7L3,LRIG1,MADD,NR4A3,NFKBIZ,CABIN1,ST3GAL1,ESYT2 |
| 6.888e-04 | -7.28 | GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN | 192 | 45 | 17758 | 2588 |
TRAPPC10,HEXB,CDCA8,NRG2,DHRS3,EPM2A,SH2D4A,CDK14,TMEM63A,KIF5B,ZYX,CCNA2,FUT2,PIK3AP1,KNDC1,SGK3,STEAP2,FAM63A,ABCD1,GLB1L2,HSPA13,NFU1,OSBPL7,IL1RAP,UFD1L,PRSS23,RGMB,MPP1,PBK,PTPN9,RAPGEF2,RANBP9,NIN,IRS2,TRAM2,TMEM30A,SLC2A6,ARAP1,PKD2,MLKL,CENPE,TMEM120A,CPEB2,E2F8,ARHGEF4 |
| 6.888e-04 | -7.28 | GSE5960_TH1_VS_ANERGIC_TH1_DN | MSigDB lists | GSE5960_TH1_VS_ANERGIC_TH1_DN | 192 | 45 | 17758 | 2588 |
BIN1,SERPINE2,CHCHD7,GNPDA1,SLC41A1,PNPLA2,F11R,PRKACA,SNX9,REPS1,SDF4,PLS3,IER3,ATP6V0B,SLC44A1,PAPSS1,TNPO2,TNFRSF18,RPN2,PHKA2,NFKB2,KANK3,TMBIM1,ABCC1,CXXC5,NFE2L1,PDK3,CYB5A,GABARAPL1,AMZ2,MDK,RBL1,SCG2,STAT6,CORO1C,NR4A3,PLXND1,ITGAV,NRGN,F2RL1,SHOX2,CD81,TOB1,CAPN1,ACOT7 |
| 6.888e-04 | -7.28 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP | 192 | 45 | 17758 | 2588 |
FAM189A2,CALB2,SOX9,XIAP,ASAH1,AES,IFT27,CARD10,TFAP4,RPS6KA2,ITGA3,ADRBK1,MGAT1,GATA2,LYPD3,SIVA1,BDH1,ADAM15,AHCY,ECE1,SYK,SUN2,PGM1,ALDH2,RIPK2,PTPN9,CASP9,PYGL,UBAC1,ESYT1,PRKRA,ZFAND5,H2AFV,DCP2,PLEKHB1,MAGED2,FYN,TBX1,SLC4A3,CSTF2,UNC5B,LTA4H,USF2,TRAF5,ACOT7 |
| 6.888e-04 | -7.28 | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP | 192 | 45 | 17758 | 2588 |
SIGIRR,SLC35D2,ENO2,EFHD2,IL27RA,PLA2G16,NUCB2,PKN1,DENND2D,LTBP3,ZYX,PSMD1,TIMP1,P4HB,PLEKHF1,FAM102A,IL17RA,ETHE1,CITED2,MYBL1,MPHOSPH9,SMARCA2,COL6A2,IFITM3,TESK1,DENND1B,HMG20B,PRKCQ,PLEKHB1,NMT2,OPTN,ATP13A2,TXK,MAGED2,LDLRAP1,UAP1,LRIG1,INPP4B,CABIN1,STK39,CTSA,B4GALT3,NDFIP1,NRBP1,RTN3 |
| 6.888e-04 | -7.28 | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDM_UP | 192 | 45 | 17758 | 2588 |
LASP1,ADD1,FAM160B1,MRPS15,THRA,ARMC7,GMPR,EFHD2,IL18,TGFBR1,FAM198B,SEPP1,LTBP3,XPR1,CAPN2,LLGL2,SH3BP1,CD22,IL6ST,MITF,DLG1,TMEM51,FAR1,ITM2C,DDX59,SYPL1,MBP,SLC37A1,KIF20A,ASPM,CORO2A,OXR1,CBX6,BNIP3L,RNPEP,SLC44A3,ANKRD10,NCOA3,TMEM50B,RPL12,NGFRAP1,RAB31,PLIN3,CCNB2,MYL12B |
| 6.935e-04 | -7.27 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | 176 | 42 | 17758 | 2588 |
SPRED1,TRIM2,FAM189A2,SOX9,SOD2,NDRG2,KCNC4,ELF3,SLC25A45,ITGB8,GPC3,BHLHE41,ALDH1A3,ELF5,FOSB,ACTA2,CDH3,STEAP3,SOCS5,DUSP1,ZNF462,USP31,CYB5R2,RAPGEF2,FOS,ZDHHC3,NFIB,ATP10D,FZD7,EGFR,SPIN3,PLEKHH2,SERPINA1,PDLIM3,RND3,MAP2,HOXA9,MYLK,FAM110C,KLK7,MAFF,MAMDC2 |
| 6.942e-04 | -7.27 | cell cortex | cellular component | GO:0005938 | 234 | 53 | 17570 | 2579 |
LASP1,FBLIM1,NF2,TRIP10,ARHGEF7,TRAF2,EPS8,FLOT1,ITPR2,GPSM2,SPTB,CAPN2,ADD3,SCNN1A,CDH1,CTNNB1,CTGF,FRY,STIM1,LLGL2,RALB,CABP1,CALD1,FRYL,EXOC8,CTTN,MYRIP,FLOT2,GM2A,TLE6,MYO5B,RHOA,MPP1,ITCH,DMTN,DSTN,SEPT6,CRIP2,EZR,PLS1,ANLN,TSC1,PLEKHH2,FGFR2,FAM110C,PKD2,SPTBN5,ARF6,SHROOM2,NDFIP1,NRBP1,COBL,MELK |
| 6.978e-04 | -7.27 | CAGTATT,MIR-200B,MIR-200C,MIR-429 | MSigDB lists | CAGTATT,MIR-200B,MIR-200C,MIR-429 | 452 | 91 | 17758 | 2588 |
LMO7,TRIM2,LFNG,DGKA,XIAP,MPP5,EGR3,VASH1,SPTB,NCS1,PLS3,KCTD15,RPS6KA2,DACT1,REEP1,TLN2,MYT1,CYP1B1,KRT80,SEC23A,ASXL1,CDYL,PRKAR2B,ANLN,SESN1,DAG1,ULK2,LCP1,NIN,HLF,MPRIP,KLF12,MAP2,PLK2,CORO1C,CAB39,CBX4,FGD1,CDK17,DCAF7,ZCCHC24,LRP4,EPS8,ETV5,PM20D2,INTS8,SBF1,ETS1,PSIP1,NRP2,PDCD10,PPP1R10,CDK16,GATA2,BHLHE41,MXD3,KLF9,PIKFYVE,CITED2,CLIP2,NCOA2,IGSF3,DUSP1,AMOTL2,RHOA,MMD,NR3C1,AMFR,OXR1,FXR2,PDIK1L,RANBP9,LEPR,SLC6A6,FGFR2,RND3,HNRNPH2,RAP2C,ITPR1,DCUN1D1,EFNA1,FHL1,GEM,CEP41,TOB1,OCLN,PKIA,RPS6KA3,NIPA1,NGEF,EGLN1 |
| 6.991e-04 | -7.27 | PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1 (alpha)) | protein interactions | 5295 | 192 | 48 | 16036 | 2547 |
WASF3,INPPL1,INPP5D,RET,ERBB2,TGFBR1,TEC,FLT3,PCBP1,SH3KBP1,SLC9A2,RB1,IGF1R,CTNNB1,PIK3AP1,CD22,IL6ST,PIK3CA,TUBG1,DAB2IP,PIK3CD,ERBB3,SYK,IL1RAP,NUP85,SIRT1,ADAMTS2,AKT1,TNIP1,PIK3R1,EZR,CD40,CBL,BCAR1,RASA1,EGFR,IRS2,IL1R1,FYN,INSR,JAK1,HTT,FGFR2,AXL,NFKBIA,MAP3K5,JAK3,GAB1 |
| 7.033e-04 | -7.26 | LEIN_PONS_MARKERS | MSigDB lists | LEIN_PONS_MARKERS | 89 | 25 | 17758 | 2588 |
ADAMTS2,LGALS8,TSC22D3,CALM1,EIF5A2,PHOSPHO1,CALM3,TNS1,BAIAP3,ESYT1,LTBP3,CD83,DPYSL3,CALM2,MAGED2,KIF5B,ENDOD1,SPP1,DNPEP,STEAP2,NRG1,HMGA1,MARCH2,PANX2,CAPN1 |
| 7.033e-04 | -7.26 | KEGG_PROSTATE_CANCER | MSigDB lists | KEGG_PROSTATE_CANCER | 89 | 25 | 17758 | 2588 |
CCNE2,PDGFC,NKX3-1,HSP90B1,AKT1,CASP9,PIK3R1,TP53,ERBB2,TCF7,PDGFB,GSTP1,EGFR,PDGFA,CCND1,RB1,IGF1R,CTNNB1,PTEN,FGFR2,NFKBIA,E2F1,PIK3CA,CDKN1B,PIK3CD |
| 7.069e-04 | -7.25 | BENPORATH_SOX2_TARGETS | MSigDB lists | BENPORATH_SOX2_TARGETS | 696 | 132 | 17758 | 2588 |
EXPH5,UGT8,PNISR,TRIM24,CNOT8,ARFGEF1,KIF2C,MORF4L2,KIF26A,RAB15,CTGF,UBE2T,DPYSL2,SLC44A1,PSMC2,DNM2,TUBG1,ODF2L,CASP9,CDYL,ROR1,PIF1,LOXL2,SAV1,ICMT,ADRBK2,CDK1,COL12A1,ARF4,DPYSL3,SFXN1,TBC1D17,KCNMB4,GNPTAB,MAP3K11,PRKCDBP,PCSK5,PRSS8,LASP1,CDK17,PPP1R2,GGA1,TMEM55B,PDCL,DHRS3,BMP2,CALR,VASP,CA2,CYR61,FBXL14,FXYD5,KNTC1,UFD1L,CEP89,KIF20B,EPHA1,KDM3A,RASA1,MOSPD3,MAGED2,CACHD1,TJP3,C1orf21,CBX5,ARHGAP11A,PLEKHG3,SPRED1,MTM1,GRHL2,ERBB2,GRK6,EGR3,PCBP1,PER2,RAD23A,CDK14,CCND1,RBM23,SCNN1A,FICD,CDH3,VAT1,ETHE1,ARL4D,EGLN3,DVL2,CTH,TBC1D10B,SEPT6,CYB5R2,FOXJ2,SAT1,NUSAP1,ALCAM,FZD7,TLE1,KLF5,ZNF701,PRKAR1A,IER5L,SORT1,HSP90B1,HDGFRP2,PPP2R3A,HDAC9,TMEM63A,TOP2A,AKIRIN1,ADD3,CDK16,PPP1R10,BMP7,SGK3,ALDH7A1,IGFBP2,HSPA13,AK3,HEXIM2,FAM134C,NFE2L3,BCL9,KIF11,PITX2,BTG1,SERPINA1,FGFR2,PGM2L1,PPP2R3C,CEP41,UBE2C,JARID2 |
| 7.107e-04 | -7.25 | cytoplasmic side of plasma membrane | cellular component | GO:0009898 | 154 | 38 | 17570 | 2579 |
TNK1,FARP1,TRAF2,IQGAP1,RASA2,GNAL,RACGAP1,TEC,SNX9,CACNB4,SPTB,CDH1,PTEN,CDK16,SNX18,CABP1,DLG1,DAB2IP,TIAM1,SYK,GM2A,S100A6,EZR,YES1,GNA11,RASA1,TXK,GNAS,RGS9,FYN,LDLRAP1,JAK1,ARRB1,CHMP4B,GEM,TRAF5,JAK3,ESYT2 |
| 7.121e-04 | -7.25 | GTPase regulator activity | molecular function | GO:0030695 | 286 | 63 | 16491 | 2452 |
ARHGAP11A,ARAP3,DEPDC1,ARHGEF11,TBC1D1,RASA2,RALBP1,IQGAP1,ARFGEF1,RGS20,RASGRP3,RACGAP1,GPSM2,ELMOD2,SYDE2,SIPA1L2,ACAP2,ARHGAP42,RGS12,RABEP2,LLGL2,RINL,SH3BP1,OCRL,RGS3,TBCD,FAM13B,RANBP1,RGS5,DAB2IP,RP2,IQGAP3,ALS2CL,TBC1D10B,DOCK4,ARAP2,TBC1D8B,RAPGEF2,ARHGDIB,GRTP1,RHPN1,ABR,RASA1,ARHGAP35,ARHGAP24,TSC1,PLEKHG6,RGS9,TBC1D17,ARHGEF19,SIPA1L1,RIN3,SH3BP4,ARAP1,ARRB1,AGFG2,ARFGAP3,ARHGAP4,RGS14,TBC1D4,RAP1GAP,STARD13,CPEB2 |
| 7.164e-04 | -7.24 | MODULE_129 | MSigDB lists | MODULE_129 | 214 | 49 | 17758 | 2588 |
WASF3,PAPSS2,DNAJB2,ITGA6,ETV5,PDGFRL,BCL2L1,BAIAP3,B4GALT4,TSPAN7,HDAC9,BMP2,SPP1,DOPEY2,TPST1,ALDH7A1,LGMN,ARL4D,TSPAN1,LOXL1,PTPRE,ZNF365,IL1RAP,MX1,CASK,ING1,TCFL5,BCL9,SYNE2,GRIN1,IFIT3,LEPR,FZD7,DPYSL3,BCAR3,MDK,TRIM9,PIAS3,PROM1,GPRC5B,P4HA2,MYLK,NRG1,SERPINI1,EFNA1,TMEM8B,ARSB,ST3GAL1,ARHGEF4 |
| 7.182e-04 | -7.24 | protein N-linked glycosylation | biological process | GO:0006487 | 188 | 45 | 16441 | 2455 |
CMAS,TRAPPC10,MAN1A2,GNE,PDIA3,CTSZ,NANS,MGAT5B,B4GALT4,CALR,CTSC,MGAT1,ALG13,MGAT4A,FUT8,UBE2J1,RPN2,STT3B,TFG,LMAN1,PPP6R1,SLC35A1,MGAT5,TMED2,GFPT1,SEC23A,MLEC,MGAT4B,COL7A1,SLC17A5,MCFD2,VCP,FUCA1,MAN2A2,DDOST,SERPINA1,UAP1,AREG,DOLPP1,GNPTAB,GLB1,CTSA,ALG2,B4GALT3,ST3GAL1 |
| 7.197e-04 | -7.24 | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP | 187 | 44 | 17758 | 2588 |
SORBS1,ST13,ARMCX3,EPAS1,ZCCHC24,ETV5,PDIA5,FLOT1,GMPR,KIF23,NDUFA4,BLCAP,SNN,SEPP1,PDIA4,SCML1,TNS3,BHLHE41,MITF,DAPK1,DUSP10,WBP4,TFG,CLIP2,OSGIN1,SOCS5,LOC81691,MRPS33,LGALS8,LAP3,UBAC1,ESYT1,KLHL2,GALNT3,DCTN6,FECH,MFAP3L,TMEM164,H1F0,HNRNPH2,PPM1H,SH3BP4,SERPINB6,HSPB1 |
| 7.197e-04 | -7.24 | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDM_DN | 187 | 44 | 17758 | 2588 |
CCNI,IL15,RUSC2,SHPRH,SERPINB9,ABCG2,ARFGEF1,CD274,LACTB2,NFAT5,TMCC3,ATP6V0B,NAPG,TAF1B,IGSF9,SNX18,FCHO1,SRP54,HLA-C,SLC35A1,RASGRP1,TBC1D10B,HMMR,SYPL1,HPS3,IFITM3,ADCK3,AMFR,RNF11,PRICKLE1,FNDC3A,NDRG3,C3orf58,ABR,FZD7,SOCS3,JAK1,GNPTAB,PIAS2,SFMBT1,AGFG2,CMPK2,IFIH1,RNF146 |
| 7.197e-04 | -7.24 | GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN | MSigDB lists | GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN | 187 | 44 | 17758 | 2588 |
ZMAT1,UNC93B1,CDS2,PCOLCE,ARHGEF3,TTC39B,CPT2,CNOT8,ARMC7,BLCAP,FAM91A1,SEPP1,IL18R1,MDM1,ZFP36,SLC30A6,PRKCI,AKR1B1,TNFRSF18,CNOT6L,PLCB2,OSGIN1,GM2A,ATP2B1,UPF3A,MBP,BTNL9,OSTM1,ITCH,STAT4,ERP44,FUCA1,BANK1,CTNS,STK38,SIPA1L1,APPL2,DGAT2,ERAP1,ARF6,TMEM120A,NRBP1,RPS6KA3,ARHGEF4 |
| 7.206e-04 | -7.24 | RABBD | prosite domains | PS50916 | 12 | 7 | 11866 | 1802 |
EXPH5,SYTL4,MLPH,MYRIP,SYTL3,RIMS2,SYTL2 |
| 7.220e-04 | -7.23 | positive regulation of transcription from RNA polymerase II promoter | biological process | GO:0045944 | 1009 | 187 | 16441 | 2455 |
CCNC,ACVR1,AGRN,EPAS1,HEXB,GATA3,MORF4L2,TFAP2E,TP73,EPCAM,HELZ2,HSF2,CTNNB1,GRHL1,NPNT,PSMC2,MITF,FOSB,ELF5,IRF2,ASH2L,ARNT2,MYBL1,ZNF462,THRB,PCGF5,SMARCA2,TNIP1,ASXL1,NFE2L1,TFAP2C,EAF2,LDB2,ARF4,AHRR,KLF12,TBX1,NOD2,HDAC1,RNASEL,F2RL1,E2F8,PSMC1,MAFF,HOXC13,NR2C2,DDX58,KLF2,RUNX2,PPP1R12A,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,BMP2,TFAP4,RB1,CYR61,GATA2,EBF4,MYDGF,WNT3A,MAPK7,ELK3,SALL4,STAT4,MYBL2,ELK1,KDM3A,NFIB,EGFR,ONECUT1,NCOA3,ETS2,SETD3,NFKBIA,PIAS2,NLRC5,NR4A2,RARG,RPS6KA3,TMEM173,RAD21,IRF1,PAX6,ARMCX3,GRHL2,FOXM1,THRA,RPS6KA1,TP53,CCNL1,OSR2,LPIN3,SS18,LMO4,SMO,DAB2IP,ZBTB49,TWIST1,NOTCH3,NFKB2,ETV4,SIRT1,RIPK2,AKT1,FOXJ2,PYGO1,GTF2A2,CD40,EBF2,NFIX,JADE1,HSF4,RBL1,STAT6,WWTR1,STAT1,KLF5,NRG1,IRF7,AKNA,ARNT,GLIS3,NKX3-1,CKAP2,PBX3,HMGN3,ETS1,NFAT5,TEAD3,SIX4,WWP2,GBX2,IRF2BPL,TOP2A,E2F7,BMP7,MCF2L,TOX2,GTF2F2,TFAP2A,ERCC2,CITED2,NCOA2,HES1,DCAF6,CASK,PLSCR1,WNT10B,NR3C1,BCL9,TEF,NR4A1,PIK3R1,GRIN1,RGCC,PPARA,MAML2,YES1,FOS,ABLIM2,TXK,CRTC2,PITX2,FGFR2,ACVRL1,NR4A3,E2F1,ARRB1,PKD2,GPER1,HMGA1,OSR1,FZD5,ZMIZ1,SOX8,CD81,SHOX2,USF2,AHR,FOXA1,USP16,RGMA |
| 7.231e-04 | -7.23 | LANDIS_BREAST_CANCER_PROGRESSION_UP | MSigDB lists | LANDIS_BREAST_CANCER_PROGRESSION_UP | 43 | 15 | 17758 | 2588 |
GALNT3,CMAS,SHROOM3,CD82,KCNN4,DAP,FXYD3,AIM1,LITAF,TFAP2C,CYB561,ACSL4,NUCB2,FAM134B,IRX3 |
| 7.235e-04 | -7.23 | glutamate receptor binding | molecular function | GO:0035254 | 34 | 13 | 16491 | 2452 |
GNAS,CALM2,IL1R1,RASGRF1,PLCG1,CABP1,CALM1,DLG1,GRIN1,NETO2,CALM3,DLG3,FLOT2 |
| 7.247e-04 | -7.23 | organonitrogen compound catabolic process | biological process | GO:1901565 | 346 | 74 | 16441 | 2455 |
AGRN,HSPG2,AASS,CRYM,HEXB,MCCC1,OAT,SDC1,NUDT12,TYMP,ENTPD4,GOT1,ECE1,PDE4D,ETHE1,NAGA,APOBEC3G,GM2A,ERAP2,CTH,CHP1,ENPP4,SAT1,CDA,CCBL2,VCP,NEIL1,ALDH5A1,IDE,HPSE,ABHD12,MAOA,GLA,LTA4H,ALDH6A1,DHPS,GCAT,HAL,SDC4,BLVRB,ASL,APOBEC3H,SGPL1,GNS,GPC3,GALNS,PCYOX1,AHCY,HMGCL,ALDH7A1,ACAD8,GAD1,MCCC2,FAH,HMMR,PRODH,SHMT1,GUSB,PDE5A,BLVRA,RNPEP,AMDHD1,PDE11A,FUCA1,NT5C2,DDAH1,NUDT16,ACADSB,PLA2G15,ERAP1,GLB1,ARSB,SAT2,XDH |
| 7.266e-04 | -7.23 | regulation of cell development | biological process | GO:0060284 | 793 | 151 | 16441 | 2455 |
EMX1,SSH1,EPHA4,RET,GATA3,PLXNA1,CAMK1D,FAM101B,GRM5,NCS1,TP73,CTNNB1,CDKL5,IL6ST,DPYSL2,DNM2,DUSP10,TACSTD2,SEMA3G,CTTN,PACSIN1,TIAM1,KLK6,SAV1,CDK1,RHEB,ULK2,IRX3,DPYSL3,GPRC5B,PLK2,LIMK1,ITPKA,ARF6,LZTS1,GRN,SEMA6B,SERPINE2,PPP1R12A,SOX9,ETV5,FBLN1,FAM21C,BMP2,CALR,SPP1,ITGA3,GATA2,MEGF8,VASN,KIF13B,PRKCI,SORL1,TNFRSF12A,NPTN,NTN1,WNT3A,CCDC88A,RIMS2,EPB41L5,MMD,MFI2,HMG20B,PDE5A,KIF20B,ILK,CDK5R1,PTPRF,AP1AR,NCOA3,SEMA4D,CSF1,TMEM30A,AURKA,EFNA1,GDF11,ARPC2,SEMA3A,FOXO6,PAX6,NF2,TP53,PER2,KIF14,SMO,BCL6,DAB2IP,DIXDC1,TWIST1,NOTCH3,SEMA3B,SSH3,TIMP2,AKT1,DMTN,CDC20,DAG1,ARHGAP35,FYN,BHLHB9,PTK7,CORO1C,WWTR1,SIPA1L1,STAT1,TRIOBP,RAB29,NRG1,EFNA5,PLXND1,RGS14,COBL,CTDSP1,BIN1,ADGRG1,ARHGEF7,CIT,LRP4,TGFBR1,CRABP2,TEAD3,HDAC9,PTEN,KNDC1,MYCL,BMP7,KIAA0319,BAX,ITM2C,TTPA,GFI1,TRIM62,TLE6,FAM134C,TGIF1,HES1,RHOA,RAPGEF2,ASPM,GRIN1,RGCC,MAP1B,CDK5RAP1,CNOT2,GPER1,SOX8,ARSB,SHOX2,L1CAM,FOXA1,NGEF |
| 7.271e-04 | -7.23 | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | MSigDB lists | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | 99 | 27 | 17758 | 2588 |
PLK1,AKT1,TP53,FHL2,HMG20B,CCNB1,ELK1,CDC25C,BARD1,CDK1,CCND1,RB1,CCNA2,PEX5,JAK1,LMO4,NMI,NFKBIA,STAT1,E2F1,MSH2,TUBG1,HDAC1,AURKA,KPNA2,CTBP1,MSH6 |
| 7.285e-04 | -7.22 | primary neural tube formation | biological process | GO:0014020 | 92 | 26 | 16441 | 2455 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SDC4,RAB23,PRICKLE1,KIF20B,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,BCL10,TSC1,VASP,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,COBL,RARG,DVL2 |
| 7.380e-04 | -7.21 | substrate adhesion-dependent cell spreading | biological process | GO:0034446 | 38 | 14 | 16441 | 2455 |
BVES,FZD4,KIF14,AXL,VAMP3,EFNA1,ITGAV,EPHA1,MICALL2,ILK,AKIP1,MERTK,ANTXR1,FZD7 |
| 7.391e-04 | -7.21 | KEGG_FOCAL_ADHESION | MSigDB lists | KEGG_FOCAL_ADHESION | 198 | 46 | 17758 | 2588 |
MYL9,PPP1R12A,ITGA6,XIAP,ERBB2,PDGFB,ITGA2B,PDGFA,PAK6,CCND1,CAPN2,SPP1,RAC2,ZYX,VASP,ITGA3,IGF1R,CTNNB1,ITGB8,PTEN,SHC3,PAK2,COL6A1,PIK3CA,PIK3CD,PPP1CA,TLN2,RASGRF1,PDGFC,RHOA,COL6A2,AKT1,PIK3R1,ELK1,ILK,BCAR1,MYL12A,EGFR,ARHGAP35,PGF,FYN,ITGA7,MYLK,PPP1CB,ITGAV,MYL12B |
| 7.391e-04 | -7.21 | HALLMARK_APICAL_JUNCTION | MSigDB lists | HALLMARK_APICAL_JUNCTION | 198 | 46 | 17758 | 2588 |
MYL9,CD99,INPPL1,TAOK2,NF2,MPZL1,CERCAM,CALB2,SORBS3,MPP5,CD274,SIRPA,ICAM1,RAC2,ZYX,VASP,ITGA3,CDH1,PTEN,ICAM5,DLG1,ADAM15,TUBG1,CLDN4,CDH3,MAPK11,SYK,PVRL4,SGCE,PCDH1,CRB3,RASA1,EGFR,MDK,TSC1,PLCG1,LDLRAP1,PVRL2,BMP1,CTNND1,MAPK13,TMEM8B,ARPC2,SHROOM2,COL16A1,MYL12B |
| 7.420e-04 | -7.21 | TPR_repeat | interpro domains | IPR019734 | 124 | 32 | 18293 | 2672 |
TTC8,ST13,CEP70,TTC39B,TMTC3,DNAJC3,KLC2,GPSM2,AIP,APPBP2,TTC21B,NOXA1,FICD,KLC3,IFIT1,TMTC1,LONRF3,EMC2,TTC7A,TANC1,NPHP3,IFIT3,TMTC2,UNC45B,SPAG1,RGPD5,PEX5,TTC12,P4HA2,CABIN1,TTC9,TANC2 |
| 7.513e-04 | -7.19 | E2F1_UP.V1_DN | MSigDB lists | E2F1_UP.V1_DN | 182 | 43 | 17758 | 2588 |
PLA2G4A,KLF2,UNC93B1,AVPI1,RUNX2,HLA-E,EPS8,ASL,IL18,NOTCH2,ITPR2,APC2,PHLDA1,FGF19,SLC35E4,XPR1,CAPN2,A4GALT,IL6ST,KLF3,FCHO1,BCL6,SGK1,ERBB3,ARL4D,CYP1B1,MX1,SEC23A,CRIP2,SLC11A2,IDH1,C18orf8,FAS,MDK,IL1R1,PTGS2,STAT6,CSF1,PLK2,LRIG1,NFKBIZ,PLXND1,B4GALT3 |
| 7.541e-04 | -7.19 | platelet-derived growth factor receptor signaling pathway | biological process | GO:0048008 | 34 | 13 | 16441 | 2455 |
PDGFA,PDGFC,PTPRJ,PTEN,IQGAP1,PDGFRL,RGS14,PDGFB,BCAR1,TIPARP,ZFAND5,GAB1,SGPL1 |
| 7.551e-04 | -7.19 | V$AREB6_01 | MSigDB lists | V$AREB6_01 | 253 | 56 | 17758 | 2588 |
CTHRC1,BMF,LRRFIP2,IGFBP6,GRHL2,TTC39B,CHCHD7,FXYD3,CAMKK1,THRA,STRN4,IRX4,GRK6,PDGFB,DDR1,HPCAL4,HDAC9,PAK6,SNX13,ITGB8,LLGL2,LYPD3,TSPAN6,TMEM62,SLC16A6,BHLHE41,SLC44A1,TFAP2A,VAT1,CDKN1B,ACSL4,MANF,WNT3A,GAD1,ETV4,STK35,TUBA4A,SOCS5,CYP26B1,OLFML2A,CXXC5,CASK,KREMEN2,CRB3,TEF,TMEM151A,LDB2,FOS,NFIB,MUM1L1,NXPH4,SP6,KIF12,MAP3K5,OSR1,HS6ST3 |
| 7.551e-04 | -7.19 | V$NFY_Q6_01 | MSigDB lists | V$NFY_Q6_01 | 253 | 56 | 17758 | 2588 |
SLC2A4,PPP4R4,GRHL2,UGP2,CIT,SLC25A13,ETV5,PDIA3,RACGAP1,HMGN3,BAHD1,PRKACA,IFT27,CDH1,ZCCHC12,SHC3,FDXR,PASK,FOSB,TMEM143,NEK2,ANKRD12,GLB1L2,RFX5,KLF9,DLG3,MAPK7,SPRY2,PLK1,DPYSL5,SUN2,GCA,RHOA,MLEC,KIF20A,PIK3R1,KBTBD8,PIM3,LDB2,BORA,KDM3A,TYSND1,VCP,PPP2R5A,DOLPP1,WDR19,AGFG2,FAM117A,DHTKD1,HDAC1,NDE1,STARD13,E2F8,JARID2,NR2C2,DOCK9 |
| 7.566e-04 | -7.19 | APEH (acylaminoacyl-peptide hydrolase) | protein interactions | 327 | 40 | 15 | 16036 | 2547 |
LAMP2,CYHR1,ZYX,SHMT1,SERPINE2,PFKL,LGALS8,DNM1L,TMEM62,NMI,TBCD,STAT1,CTTN,VPS26A,H1FX |
| 7.586e-04 | -7.18 | response to oxygen levels | biological process | GO:0070482 | 291 | 64 | 16441 | 2455 |
CASP3,SLC2A4,EPAS1,SLC2A8,NDRG1,TP53,ITPR2,CCNB1,PDGFB,PICK1,CYP1A1,TGFBR3,CTGF,P4HB,CDKN1B,TWIST1,ARNT2,EGLN3,SIRT1,AKT1,TCEB2,PRKCQ,SLC11A2,LOXL2,ATP1B1,SOCS3,EDNRA,PTGS2,ARNT,HSP90B1,NKX3-1,PINK1,CPEB4,PRKAA1,SELL,ETS1,LMNA,ICAM1,CAPN2,BMP2,IRAK1,ADORA1,PTEN,VASN,BMP7,CST3,AHCY,ERCC2,CITED2,HP1BP3,RHOA,ADAM17,RGCC,PPARA,PDK3,FAS,PLOD2,ITPR1,UBE2D2,E2F1,NR4A2,CPEB2,EGLN1,DRD1 |
| 7.587e-04 | -7.18 | FERM_C | pfam domains | PF09380 | 26 | 11 | 16629 | 2504 |
EPB41L5,FARP1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 7.599e-04 | -7.18 | V$CIZ_01 | MSigDB lists | V$CIZ_01 | 220 | 50 | 17758 | 2588 |
HOXB7,CHCHD7,TAB3,CAST,DGKA,WDTC1,NRG2,INTS8,PDGFB,SYTL2,WWP2,CCND1,CDKN2C,FOXP2,PDCD10,FAM46A,PPP1R10,STIM1,FLRT3,RIMS3,CAPG,PDE4D,NCAM1,CCDC88A,CKAP4,IGSF3,LAMP2,SMARCA2,HN1L,BCL9,PLEKHO1,PRICKLE1,C2orf69,NFIX,TMEM164,LDLRAP1,KLF12,CCDC6,MYLK,TDRD7,NR4A2,PPP2R3C,EFNA5,CDK18,RBM43,SEMA3A,PPP2R5D,TOB1,COL16A1,KLF7 |
| 7.615e-04 | -7.18 | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | MSigDB lists | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | 75 | 22 | 17758 | 2588 |
SMARCA2,GATA3,PHLPP1,RASA1,MECOM,MDK,HLF,TIMP3,PLOD2,FAM3C,LRIG1,INPP4B,MSH2,PPM1H,FAM117A,ZNF165,SERPINI1,HSPA13,KLF9,F2RL1,HSPB1,CCDC88A |
| 7.618e-04 | -7.18 | epithelioid | COSMIC cancer mutations | epithelioid | 39 | 14 | 17775 | 2585 |
LRRC45,TSC1,RB1,PLCG1,SS18,CTNNB1,CDH1,AKT1,PTEN,PIK3CA,TP53,IDH1,GNA11,TLL2 |
| 7.623e-04 | -7.18 | protein N-linked glycosylation via asparagine | biological process | GO:0018279 | 178 | 43 | 16441 | 2455 |
CMAS,TRAPPC10,MAN1A2,GNE,PDIA3,CTSZ,NANS,B4GALT4,CALR,CTSC,MGAT1,ALG13,MGAT4A,FUT8,UBE2J1,RPN2,STT3B,TFG,LMAN1,PPP6R1,SLC35A1,MGAT5,TMED2,GFPT1,SEC23A,MLEC,MGAT4B,COL7A1,SLC17A5,MCFD2,VCP,FUCA1,MAN2A2,DDOST,SERPINA1,UAP1,AREG,DOLPP1,GLB1,CTSA,ALG2,B4GALT3,ST3GAL1 |
| 7.638e-04 | -7.18 | cell adhesion molecule binding | molecular function | GO:0050839 | 184 | 44 | 16491 | 2452 |
NF2,ITGA6,NDRG1,SELL,FBLN1,EMP2,ICAM1,NEO1,EPCAM,CALR,CD46,NOV,ITGA3,CDH1,CTGF,CTNNB1,CYR61,NPNT,P4HB,ICAM5,CD9,FXYD5,ADAM15,NPTN,CPE,SYK,SMAGP,P2RX4,PVRL4,FBLN5,ADAM17,TIMP2,CTNNAL1,UTRN,EZR,ERBB2IP,ILK,CDK5R1,PROM1,PVRL2,PLPP3,CTNND1,L1CAM,COL16A1 |
| 7.643e-04 | -7.18 | human chrXq22.1 | chromosome location | human chrXq22.1 | 30 | 10 | 26250 | 2805 |
XKRX,ARMCX3,TIMM8A,CENPI,PCDH19,CSTF2,TRMT2B,TCEAL8,SRPX2,LINC00630 |
| 7.705e-04 | -7.17 | response to external stimulus | biological process | GO:0009605 | 2118 | 366 | 16441 | 2455 |
HSPG2,TRIM5,DNAJC3,NRG2,GATA3,PSME1,IL18,PLXNA1,CCNB1,KIF26A,CMTM6,ELMOD2,PICK1,CALM2,PHYHIP,TYMP,CYP1A1,PSMD1,ELMO2,ZFP36,ALDH1A3,FOSB,CRY2,SEMA3G,PPP1CA,PIK3CD,TIAM1,IL10RB,APOBEC3G,METAP2,ACVR1C,CASP9,BNIP3L,SLC35C1,MYOM1,POR,ULK2,ABR,PLCG1,LIMK1,MYLK,NOD2,RNASEL,UNC5B,HSPB1,F2RL1,DDX58,SEMA6B,SCN5A,NUAK1,ITGA6,HLA-E,SOX9,PRKAA1,SLC1A3,ATG4A,MECOM,RAC2,ZCCHC17,CYR61,RPL39,FLRT3,FAM13B,OPN3,ALPK1,CACNA1D,CNGA1,NCAM1,NUP85,MAPKAPK3,CALM1,ANO6,NPC2,EPHA1,DPYSL4,GNA11,PSMA4,NFIB,RHOB,RASA1,FAS,FNTA,SEMA4D,MATN2,MDH1,NR4A2,EFNA1,B4GAT1,ARPC2,IFIH1,TRPC3,RPS6KA3,TMEM173,IRF1,SPRED1,NQO1,THRA,RPS6KA1,RALBP1,BCL2L1,EGR3,CDS1,APOBEC3B,CCND1,NOV,RALB,DAB2IP,PDE4D,IFIT1,EPHB4,ACSL4,LRP11,RASGEF1A,DLG3,CDKN2D,ETV4,SEMA3B,ATG4D,MX1,DOCK4,COL6A2,RIPK2,APOBEC3D,LGALS8,PRKCQ,ATP1B1,RAB38,ALCAM,CMTM7,EPHA10,IRS2,FYN,JAK1,CDK19,SHROOM3,AXL,STAT1,PPP1CB,NRG1,DENND5B,OTUD5,PLSCR4,SDC4,HABP4,HERC5,APOBEC3H,ETS1,GSTP1,FGF19,EFNB1,ICAM1,HLA-A,RND1,NEO1,CXCL16,FAM111A,ANK1,OXCT1,GNB5,IRAK1,PTEN,GPC3,CST3,IGFBP2,MAPK11,ERBB3,GFI1,TTPA,FARP2,RASGRF1,ARHGEF28,B3GNT2,PLSCR1,RAPGEF2,GRIN1,YES1,FOS,ABLIM2,CNTNAP1,PITX2,RGS9,TIMP3,FGFR2,PRDX3,SLC35B3,NR4A3,RYK,ERAP1,GRIN2D,ITGAV,HMGA1,CMPK2,FZD5,ARSB,USF2,WDR45B,RGMA,MYL9,UNC93B1,CASP3,AGRN,EPHA4,LMCD1,NENF,CACNB4,PDGFB,MAP1LC3B,SDC1,SPTB,TMC1,RPS6KA2,NPNT,SHC3,DPYSL2,PSMC2,DLG1,TRPC1,DUSP10,TNFRSF18,NTN4,MYH14,RASGRP1,SOD1,ITCH,RNF165,EZR,PRKRA,PLEKHB1,OPTN,DPYSL3,WIPI1,PIEZO1,MYL12B,PSMC1,RRAGD,PRKAA2,LGALS3,SERPINE2,RASA2,PSMD7,CALM3,CNTNAP2,PHLPP1,DHRS3,DUSP5,ANO1,CORO1B,SPP1,VASP,IGF1R,COL6A1,PAK2,FNIP1,AHCY,PIM1,WNT3A,NTN1,SLC12A2,PSMA5,DPYSL5,RGMB,SCRIB,EIF2AK1,IFIT3,RANBP9,EGFR,CDK5R1,NMT2,FECH,MAPKAPK2,NFKBIA,NLRC5,PITPNA,PLD1,SHROOM2,JAK3,SEMA3A,KLF7,DRD1,GAS2L1,IL15,PSME2,TP53,ERBB2,P2RX7,IL27RA,RASGRP3,ARHGEF16,IER3,PDGFA,ARTN,PLCG2,SRR,OAS3,NFKB2,LOXL1,F2R,FRS3,SIRT1,AKT1,PTGER4,ERBB2IP,CD40,DAG1,MYL12A,ARHGAP35,SOCS3,PTGS2,ATP1A1,PTPRJ,ABHD12,PSMD3,IRF7,SPTBN5,EFNA5,PLXND1,ABCA1,CMTM4,GSDMD,COL9A3,ANXA3,CPEB4,CD63,ARHGEF11,DAP,CTSB,ARHGEF7,SERPINB9,PSMD10,COL4A5,IL22RA1,XPR1,NRP2,ITGA2B,GBX2,KIF5B,ADORA1,BMP7,TFAP2A,ACTA2,HMGCL,SYK,CAMK2G,ADAM17,RHOA,PSMB4,IFITM3,PLAUR,NR4A1,LITAF,PPARA,FXR2,BBS2,BCAR1,BCL10,HLA-B,CD8A,SCG2,CTSV,FGF18,PGRMC1,ARRB1,PKD2,PTGES,L1CAM,NGEF |
| 7.710e-04 | -7.17 | PID_PTP1B_PATHWAY | MSigDB lists | PID_PTP1B_PATHWAY | 52 | 17 | 17758 | 2588 |
TXN,RHOA,AKT1,PIK3R1,YES1,BCAR1,PDGFB,LEPR,EGFR,ITGA2B,SOCS3,INSR,FYN,CSF1,PIK3CA,SPRY2,CAPN1 |
| 7.710e-04 | -7.17 | PRAMOONJAGO_SOX4_TARGETS_UP | MSigDB lists | PRAMOONJAGO_SOX4_TARGETS_UP | 52 | 17 | 17758 | 2588 |
TRIM8,NDRG1,SOD2,AK4,GDF15,CCNL1,DUSP4,PHLDA1,KDM3A,PHF1,IER3,BTG1,RND3,NAB2,FGD6,TIPARP,MAFF |
| 7.713e-04 | -7.17 | antigen processing and presentation of peptide antigen via MHC class I | biological process | GO:0002474 | 102 | 28 | 16441 | 2455 |
SEC23A,SEC61B,PSMB4,SEC61G,HLA-E,PSME2,HLA-F,UBE2A,PSMD7,TAP1,PDIA3,PSMD10,PSME1,PSMA4,BCAP31,HLA-A,CALR,HLA-B,TAPBP,PSMD1,PSMD3,PSMC2,ERAP1,ITGAV,HLA-C,PSMC1,ERAP2,PSMA5 |
| 7.727e-04 | -7.17 | human chr6p23 | chromosome location | human chr6p23 | 12 | 6 | 26250 | 2805 |
GMPR,RNF182,KIF13A,MCUR1,RANBP9,CD83 |
| 7.727e-04 | -7.17 | human chr3q25.31 | chromosome location | human chr3q25.31 | 12 | 6 | 26250 | 2805 |
PLCH1,CCNL1,LINC00886,LINC00880,TIPARP,C3orf33 |
| 7.735e-04 | -7.16 | transferase activity, transferring hexosyl groups | molecular function | GO:0016758 | 200 | 47 | 16491 | 2452 |
UGT8,LFNG,GALNT12,XYLT1,HEXB,MGAT5B,POMGNT1,B4GALT4,EXT2,CHPF,B4GALNT1,B3GALNT1,TYMP,FUT2,MGAT1,A4GALT,XYLT2,MGAT4A,ALG13,FUT8,FUT1,GYS1,RPN2,STT3B,MGAT5,GCNT1,CHSY3,B3GALT6,PIGC,B3GNT7,B3GNT2,MGAT4B,GYLTL1B,PYGL,C1GALT1C1,GALNT7,B3GALNT2,GALNT3,DDOST,CSGALNACT1,ALG2,B4GAT1,PLOD3,POMT1,B4GALT3,POMGNT2,KDELC2 |
| 7.737e-04 | -7.16 | KISc | smart domains | SM00129 | 44 | 16 | 9131 | 1455 |
KIF3C,KIFC2,KIF20A,KIF1C,KIF23,KIF20B,KIF13A,KIF2C,KIF11,KIF26A,KIF5B,KIF13B,KIF14,KIF22,CENPE,KIF12 |
| 7.738e-04 | -7.16 | GSE30083_SP1_VS_SP2_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP2_THYMOCYTE_DN | 193 | 45 | 17758 | 2588 |
LASP1,UGT8,CPEB4,PARP14,AK7,CAST,PYROXD2,ELOVL7,TAP1,HERC6,CCDC64B,DENND2D,SPTB,DTX3L,E2F7,SLC25A45,ADD3,ADORA1,KHNYN,LHX6,FUT1,IL17RA,ABCD1,ALS2CL,REC8,RGMB,SYNE2,LITAF,TMEM151A,ESYT1,NDRG3,EGFR,KDM4D,LDLRAP1,MAP2,FAAH,FGF18,NLRC5,APPL2,CMPK2,TRAF5,IFIH1,TC2N,PRR15,ABCA1 |
| 7.738e-04 | -7.16 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 193 | 45 | 17758 | 2588 |
LZTFL1,FOXM1,TUBB4B,CKAP2,ITPR2,STIL,CENPN,TSPAN7,SSX2IP,FANCI,CCNA2,PPP4R1,OPN3,NEK2,BUB1,ALDH7A1,RFX5,BTBD3,MSH6,SMC4,CKS2,HES1,ZWINT,ALDH2,TIMP2,CTNNAL1,PBK,CDC20,ACO1,UBE2A,GALNT7,EAF2,ICMT,SPAG1,PEX5,FAM64A,CCDC6,PRDX3,PELI2,PIAS2,PGRMC1,AURKA,PKD2,DONSON,UBE2C |
| 7.752e-04 | -7.16 | positive regulation of proteolysis | biological process | GO:0045862 | 358 | 76 | 16441 | 2455 |
CASP3,DLGAP5,PSME2,RET,CUL1,PSME1,CCNB1,SNX9,BCAP31,PSMD1,CTGF,PSMC2,CDKN1B,DAB2IP,OSBPL7,EGLN3,F2R,PLK1,SIRT1,AKT1,ACVR1C,CASP9,CDC20,SLC11A2,F12,RNF19B,CDK1,VCP,NGFRAP1,PLK2,PSMD3,PSMC1,MAPK12,NKX3-1,PCOLCE,PINK1,TRAF2,DNAJB2,SH3D19,DAP,PSMD7,PSMD10,TRIB2,FBLN1,TFAP4,RB1,CARD8,CYR61,CTSC,PTEN,BAX,DAPK1,WNT3A,PSMA5,SOCS5,RHOA,PSMB4,MFI2,GCLC,NUB1,FURIN,PRICKLE1,BCL2L13,CYFIP2,PSMA4,FAS,GPLD1,BCL10,CASP7,ARRB1,AURKA,GPER1,MAP3K5,UBE2C,ESPL1,XDH |
| 7.784e-04 | -7.16 | VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1 | MSigDB lists | VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1 | 39 | 14 | 17758 | 2588 |
RAC2,CTNNB1,ITGB8,MMP17,PAK2,SMO,EFNA5,EPHB4,NOTCH2,ILK,DDR1,COL16A1,NEO1,FGD1 |
| 7.790e-04 | -7.16 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | hsa00533 | 15 | 8 | 6908 | 1076 |
B3GNT7,B3GNT2,FUT8,B4GAT1,B4GALT3,B4GALT4,ST3GAL1,CHST2 |
| 7.790e-04 | -7.16 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | ko00533 | 15 | 8 | 6908 | 1076 |
B3GNT7,B3GNT2,FUT8,B4GAT1,B4GALT4,B4GALT3,ST3GAL1,CHST2 |
| 7.791e-04 | -7.16 | placenta development | biological process | GO:0001890 | 142 | 36 | 16441 | 2455 |
GRHL2,CDKN1C,EPAS1,ST14,CTSB,PLAC1,PDGFB,SPP1,E2F7,DAZAP1,ITGB8,CYR61,GATA2,PLK4,TTPA,TMED2,MDFI,HES1,SOD1,AKT1,CCNF,EGFR,SOCS3,NCOA3,HS6ST1,PTGS2,FGFR2,PRDX3,SPINT2,CTSV,PKD2,FZD5,ARNT,E2F8,GAB1,EGLN1 |
| 7.851e-04 | -7.15 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | MSigDB lists | REACTOME_SMOOTH_MUSCLE_CONTRACTION | 23 | 10 | 17758 | 2588 |
MYL9,CALM2,SORBS1,CALD1,MYLK,CALM1,CALM3,ACTA2,SORBS3,MYL12B |
| 7.864e-04 | -7.15 | Integrated Pancreatic Cancer Pathway | WikiPathways | WP2377 | 194 | 49 | 4455 | 729 |
PRKAA2,PLA2G4A,CASP3,LTBP1,TRAF2,CD82,PTTG1,TP53,ERBB2,TGFBR1,MAPK4,TOP2A,PDGFA,CCND1,PCNA,CCNA2,NOXA1,CTNNB1,PTEN,CST3,SMO,BAX,PIK3CA,CDKN1B,MAPK7,MYT1,SIRT1,PLK1,AKT1,CASP9,GTF2A2,CDC25C,DAG1,EGFR,RHEB,FAS,IL1R1,PITX2,PTGS2,CASP7,AGPAT2,RBL1,NFKBIA,E2F1,STAT1,ABCB1,CAB39,MAP3K5,CAPN1 |
| 7.948e-04 | -7.14 | cellular carbohydrate biosynthetic process | biological process | GO:0034637 | 51 | 17 | 16441 | 2455 |
PGM1,B3GNT2,UGP2,AKT1,NANS,ISYNA1,EXT2,EPM2A,PER2,IMPAD1,CSGALNACT1,AKR1B1,PGM2L1,GYS1,GOT1,B4GAT1,PHKG2 |
| 7.948e-04 | -7.14 | TTGCACT,MIR-130A,MIR-301,MIR-130B | MSigDB lists | TTGCACT,MIR-130A,MIR-301,MIR-130B | 384 | 79 | 17758 | 2588 |
HECA,ACVR1,TRIM2,RALBP1,C5orf30,TESK2,BLCAP,BAHD1,ZFYVE9,PAK6,WEE1,NPNT,DPYSL2,ENPP5,SLC44A1,DNM2,ANKRD12,ACSL4,MARCH2,BTBD3,MYT1,TIMP2,NRBF2,RNF165,ERBB2IP,PTGFRN,ULK2,ARHGAP35,MID1IP1,CDK19,LRIG1,STARD13,NR3C2,ABCA1,RUNX2,CPEB4,SH3D19,LRP4,HABP4,PRKAA1,MIER3,TTYH3,NRP2,SLC9A2,M6PR,E2F7,BHLHE41,FAM20B,MAP3K9,TRIM3,MDFIC,NPTN,PPP6R1,MPHOSPH9,CCDC88A,SMC4,SOCS5,ACBD5,ELK3,MLEC,SYBU,KBTBD8,RUNX3,FAM73B,USP6,TSC1,BTG1,TMEM50B,CSF1,CSNK1G1,RAP2C,ITPR1,UBE2D2,PGM2L1,SFMBT1,NIPA1,SNPH,IRF1,FAM45A |
| 7.955e-04 | -7.14 | cell maturation | biological process | GO:0048469 | 132 | 34 | 16441 | 2455 |
KLF2,RUNX2,AGRN,CDKN1C,EPAS1,IL15,RET,GATA3,CNTNAP2,SEPT4,CCNB1,PRKACA,PICK1,RND1,RB1,RPS6KA2,CTNNB1,FAM20C,GATA2,LHX6,NTN4,ERCC2,FARP2,REC8,HES1,BFSP1,AXL,PTBP3,NR4A2,HOXB13,GDF11,SOX8,FZD5,FOXA1 |
| 7.957e-04 | -7.14 | SWEET_KRAS_TARGETS_UP | MSigDB lists | SWEET_KRAS_TARGETS_UP | 80 | 23 | 17758 | 2588 |
LAMP2,MYL9,SERPINE2,HSPG2,NUAK1,DNAJB2,TNS1,COL7A1,GABARAPL1,ST5,TIMP3,JAK1,P4HA2,CALD1,MATN2,BMP1,INPP4B,SGK1,CLDN4,PDXK,ITGAV,ECE1,HSPB1 |
| 7.969e-04 | -7.13 | GENTILE_UV_HIGH_DOSE_DN | MSigDB lists | GENTILE_UV_HIGH_DOSE_DN | 304 | 65 | 17758 | 2588 |
CASP3,SSH1,TRIP10,TSC22D3,C5orf30,CUL1,BLCAP,TRAPPC8,CCNB1,SS18,WEE1,CTGF,ZFP36,ATP13A3,PLK4,TIPARP,CTDSP2,CKS2,CENPA,TCEB2,SAT1,ZFAND5,LHFPL2,FZD7,TLE1,KPNA2,ARF6,MAFF,ITGA6,EPS8,GNE,ARL4C,KIF23,TRIB2,LBR,DUSP5,HOXB2,TIPRL,HMGXB4,PDCD10,GATA2,CYR61,TPST1,USP1,PIKFYVE,DUSP1,NR3C1,RAPGEF2,RHOB,STX3,STK17A,MAP1B,CNOT2,BCAR3,NCOA3,SERTAD2,UAP1,RND3,COL13A1,AURKA,ACADM,GEM,ZMIZ1,SRSF9,RAD21 |
| 7.982e-04 | -7.13 | - | gene3d domains | 2.30.42.10 | 150 | 39 | 9988 | 1574 |
FRMPD3,LMO7,USH1C,ARHGEF11,RHPN2,MPP5,APBA1,SLC9A3R2,PICK1,SNTA1,SIPA1L2,RGS12,RGS3,DLG1,TAX1BP3,DLG3,TIAM1,MAST4,DVL2,RIMS2,CASK,RAPGEF2,MPP1,SNTB2,PARD3B,SCRIB,ERBB2IP,SNTB1,PRX,RHPN1,GRID2IP,TJP3,PDLIM3,SHROOM3,LIMK1,SIPA1L1,MPP2,APBA2,SHROOM2 |
| 8.016e-04 | -7.13 | regulation of protein kinase B signaling | biological process | GO:0051896 | 122 | 32 | 16441 | 2455 |
TXN,PINK1,ARFGEF1,GATA3,TGFBR1,PHLPP1,KIAA1161,PDGFA,SESN3,IGF1R,PTEN,DLG1,MYDGF,SPRY2,SIRT1,BAG4,ILK,SESN1,DAG1,EGFR,LEMD2,PTPRJ,INSR,BANK1,HPSE,AXL,FAM110C,INPP4B,PRKCDBP,NRG1,GPER1,XDH |
| 8.043e-04 | -7.13 | nephron morphogenesis | biological process | GO:0072028 | 69 | 21 | 16441 | 2455 |
HES1,LGR4,FMN1,DCHS1,SOX9,GATA3,ILK,IRX3,CTNNBIP1,BMP2,FAT4,CTNNB1,NPNT,GPC3,SMO,DLG1,PKD2,TACSTD2,OSR1,SOX8,ADAMTS16 |
| 8.061e-04 | -7.12 | regulation of apoptotic signaling pathway | biological process | GO:2001233 | 381 | 80 | 16441 | 2455 |
ACVR1,RET,SOD2,TP53,BCL2L1,SEPT4,ERP29,BCAP31,IER3,TP73,DAPK2,SP100,CTNNB1,SRPX,P4HB,SIVA1,DAB2IP,PPP1CA,CTTN,CDKN2D,TMBIM1,CTH,SIRT1,PPIF,SOD1,AKT1,FIGNL1,PRKRA,SLC25A5,FYN,DNM1L,WFS1,MADD,NRG1,UNC5B,HSPB1,ZC3HC1,GCLM,BMF,NKX3-1,PINK1,LGALS3,TRAF2,ITGA6,BIK,PSMD10,PDIA3,TGFBR1,GSTP1,ICAM1,LMNA,TFAP4,CTSC,PTEN,PAK2,BAX,DAPK1,PLEKHF1,TMBIM6,BUB1,TNFRSF12A,MAPK7,FAIM,MAP3K7,ITM2C,PLAUR,GCLC,STRADB,PELI3,MAPK8IP1,G2E3,FAS,BCL10,HTT,SCG2,E2F1,NR4A2,ITGAV,GPER1,IFI6 |
| 8.077e-04 | -7.12 | MODULE_136 | MSigDB lists | MODULE_136 | 454 | 91 | 17758 | 2588 |
LMO7,UNKL,ACVR1,AASS,MRPS15,PNPLA2,TP53,GATA3,MAPK4,CCNL1,NANS,BAIAP3,BARD1,CMTM6,C1orf116,TYMP,CYP1A1,RNF220,ESPN,PDE4D,SCARA3,TUBA4A,ATG4D,TMCC2,TDP1,TCEB2,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRUB1,TRIM7,KDM4D,AMZ2,PTGS2,ENPP1,PI4K2B,NEIL1,MPRIP,SLC9A6,PLEKHG1,PPP1CB,RNASEL,RRAGD,PCSK5,LMTK3,CDH22,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,C9orf69,RALGPS2,CDK16,TMEM62,UBE2J1,CD9,FAR2,CITED2,ITM2C,EEF1D,MOB4,AMOTL2,HMGN5,TBC1D8B,FMN1,ADCK3,MICB,MYBL2,PIP4K2C,FURIN,DIAPH2,BCL2L13,FOS,BSDC1,RHPN1,EGFR,GALNT3,PTPRF,CD8A,PROM1,CSF1,WDR19,S100A5,FGD6,NXPH4,TMEM120A,C17orf75,PKIA |
| 8.089e-04 | -7.12 | protein autophosphorylation | biological process | GO:0046777 | 189 | 45 | 16441 | 2455 |
TNK1,PINK1,TRIM24,EPHA4,ERBB2,TEC,PRKACA,FLT3,DDR1,DAPK2,IRAK1,IGF1R,CDKL5,PAK2,PASK,NEK2,DAPK1,MAP3K9,PIM1,EPHB4,SYK,CAMK2G,MAP3K3,AKT1,MAPKAPK3,EIF2AK1,EPHA1,YES1,AURKB,PIM3,STK17B,EGFR,ULK2,TXK,MAPKAPK2,FYN,INSR,JAK1,FGFR2,STK26,KIAA1804,MAP3K11,AURKA,JAK3,MELK |
| 8.093e-04 | -7.12 | PTPRK (protein tyrosine phosphatase, receptor type, K) | protein interactions | 5796 | 92 | 27 | 16036 | 2547 |
COL6A2,TCTN2,LGALS3,LGALS8,CERCAM,CACNA2D2,PLXNA1,FBLN1,ARSK,EGFR,DNAJB9,CD109,MAN2A2,SCARB2,INSR,CTNNB1,DGCR2,ARSG,FRAS1,MEGF8,LRIG1,COL6A1,GALNS,ECE1,MOXD1,ARSB,PCSK5 |
| 8.095e-04 | -7.12 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP | 188 | 44 | 17758 | 2588 |
PRSS8,UGP2,IL15RA,ENO2,C5orf30,SELL,S100A2,DUSP5,CHST2,IER3,BTG3,TYMP,SRPX,TIMP1,AKR1B1,MTMR11,SMYD5,GM2A,FAM69A,LAMP3,MX1,PLK1,QSOX1,ZNF84,SLC39A8,ACO1,AK4,SLC11A2,PRKAR2B,FXR2,ELK1,RNF19B,BTG1,CASP7,ETS2,FGFR2,H1F0,NFKBIA,NMI,MAOA,IRF7,TRAF5,AHR,IFI6 |
| 8.095e-04 | -7.12 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP | 188 | 44 | 17758 | 2588 |
DYRK3,TXN,TRIP10,PSME2,CTSB,TAP1,SOD2,TESK2,DUSP5,CHST2,NRP2,FANCI,SPP1,BTG3,ZNF75D,ITGB8,PASK,GYS1,CDKN1B,TAGLN2,CACNA1D,NFKB2,GFI1,DUSP1,TNIP1,IFITM3,BCL9,RAPGEF2,SAT1,BNIP3L,AK4,DUSP4,IFIT3,CYB5A,CD83,TRIM9,BTG1,RND3,NFKBIA,MATN2,NR4A3,CSTF2,ST3GAL1,IFI6 |
| 8.095e-04 | -7.12 | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | 188 | 44 | 17758 | 2588 |
TXN,PPP1R2,MRPS15,PSME2,DAP,DNAJC3,TAP1,FLOT1,NDUFA4,BAIAP3,FDXR,AKR1B1,TRAM1,ITM2C,CPE,RASGRP1,SMC4,NFE2L3,TDP1,SEC61B,DSTN,USP18,ACBD3,ITCH,HTATIP2,RAD17,ICMT,SLC25A5,PSMA4,MYL12A,RHOB,FAS,LRRC42,MAGED2,CASP7,MSL1,PRDX3,WFS1,NOD2,TLE1,KPNA2,CTSA,SPCS3,ISOC1 |
| 8.162e-04 | -7.11 | CTACTGT,MIR-199A | MSigDB lists | CTACTGT,MIR-199A | 172 | 41 | 17758 | 2588 |
CDK17,PPP1R12A,CDH22,CPEB4,CCM2,SNN,NRP2,AKIRIN1,BMP2,APLP2,ITGB8,TACC2,CITED2,DLG3,TGIF1,SMARCA2,TAF5,CXXC5,CALCRL,LRRC1,ATP1B1,TANC1,CBL,KDM3A,FOS,PDIK1L,GLT8D2,RAB2B,ARHGAP24,PI4K2B,SLC4A4,PLOD2,KCNK1,CSNK1G1,PHLPP2,HOXA9,STAT6,C1orf21,LIFR,AFAP1,ABCA1 |
| 8.183e-04 | -7.11 | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | 293 | 63 | 17758 | 2588 |
LTBP1,GAA,PLSCR4,SLC2A8,ATP2C2,COL18A1,LGI3,EGR3,JAG2,PHLPP1,DNER,C11orf95,EXT2,FGF19,CHST2,MECOM,MYO5C,IGF1R,ANKS1B,FLRT3,KNDC1,TMEM37,ZRANB1,SLC12A2,ETV4,STK35,MSH6,HP1BP3,P2RX4,NFE2L3,HES1,LCA5,DCAF6,MARK1,PCDH1,ALDH2,PSMB4,FZD4,CBX6,UTRN,TMEM144,PRKCQ,TNS1,ARFRP1,ATP1B1,LDB2,MYOM1,PITX2,TAPBP,HLF,GPRC5B,SHROOM3,FAAH,ACAD10,MATN2,CLIP4,PRKCDBP,MAPK13,GLA,CBX7,OCLN,DEF6,DOCK9 |
| 8.190e-04 | -7.11 | regulation of neuron differentiation | biological process | GO:0045664 | 507 | 102 | 16441 | 2455 |
FOXO6,SSH1,RET,EPHA4,GATA3,PLXNA1,CAMK1D,NCS1,TP73,CDKL5,DPYSL2,DNM2,BCL6,DAB2IP,DIXDC1,CTTN,NOTCH3,SEMA3G,PACSIN1,TIAM1,SEMA3B,SSH3,TIMP2,AKT1,CDC20,KLK6,ULK2,DPYSL3,IRX3,ARHGAP35,FYN,GPRC5B,BHLHB9,PTK7,LIMK1,PLK2,SIPA1L1,EFNA5,RAB29,NRG1,PLXND1,ITPKA,ARF6,COBL,LZTS1,CTDSP1,GRN,BIN1,SEMA6B,SERPINE2,CIT,LRP4,ETV5,SOX9,CRABP2,BMP2,CALR,SPP1,ITGA3,PTEN,GATA2,KIF13B,BMP7,MYCL,MEGF8,KNDC1,KIAA0319,PRKCI,TNFRSF12A,NPTN,NTN1,WNT3A,GFI1,ITM2C,RIMS2,TLE6,CCDC88A,FAM134C,HES1,TGIF1,RHOA,MMD,ASPM,RAPGEF2,GRIN1,HMG20B,ILK,CDK5R1,MAP1B,PTPRF,CDK5RAP1,SEMA4D,TMEM30A,EFNA1,GDF11,SOX8,ARSB,SHOX2,SEMA3A,L1CAM,FOXA1,NGEF |
| 8.198e-04 | -7.11 | condensed chromosome, centromeric region | cellular component | GO:0000779 | 104 | 28 | 17570 | 2579 |
PLK1,REC8,ZWINT,CENPA,SPC25,HJURP,CENPC,SEPT6,NDC80,ERCC6L,NUF2,KIF2C,AURKB,CCNB1,SPDL1,SKA1,CENPN,DCTN6,KMT5C,NEK2,AURKA,BUB1,CENPE,KNTC1,NDE1,NUP37,SGOL1,NUP85 |
| 8.211e-04 | -7.10 | OS9 (osteosarcoma amplified 9, endoplasmic reticulum lectin) | protein interactions | 10956 | 61 | 20 | 16036 | 2547 |
ERLEC1,FAF2,KLK5,HSP90B1,FOXM1,CERCAM,DNAJB11,GGH,FBXO6,EGFR,VCP,NAAA,NUP210,SERPINA1,PLOD2,UBE2J1,SARAF,SERPINI1,EGLN3,EGLN1 |
| 8.220e-04 | -7.10 | HU_GENOTOXIC_DAMAGE_4HR | MSigDB lists | HU_GENOTOXIC_DAMAGE_4HR | 35 | 13 | 17758 | 2588 |
TIMP2,PTTG1,CDC20,PRC1,NEK2,CUL1,AURKA,KPNA2,KIF22,BUB1,ANLN,CDC25C,CKS2 |
| 8.221e-04 | -7.10 | REACTOME_MITOTIC_PROMETAPHASE | MSigDB lists | REACTOME_MITOTIC_PROMETAPHASE | 85 | 24 | 17758 | 2588 |
PLK1,CENPA,ZWINT,SPC25,B9D2,CENPI,CDC20,NDC80,ERCC6L,CDCA8,NUF2,KIF2C,AURKB,SKA1,CENPN,CKAP5,PPP2R5A,BUB1,KNTC1,NUP37,SGOL1,PPP2R5D,NUP85,RAD21 |
| 8.225e-04 | -7.10 | autonomic_ganglia-retroperitoneum-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-retroperitoneum-neuroblastoma | 27 | 11 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,EGFR |
| 8.225e-04 | -7.10 | dedifferentiated | COSMIC cancer mutations | dedifferentiated | 27 | 11 | 17775 | 2585 |
GNAS,RB1,SS18,CTNNB1,CDH1,PTEN,NAB2,PIK3CA,TP53,IDH1,EGFR |
| 8.272e-04 | -7.10 | extracellular matrix binding | molecular function | GO:0050840 | 47 | 16 | 16491 | 2452 |
OLFML2A,BCAM,AGRN,LGALS3,ADGRG1,DAG1,ITGA2B,LYPD5,SPP1,ITGA3,LYPD3,CYR61,ITGA7,NTN4,TINAGL1,ITGAV |
| 8.279e-04 | -7.10 | KEGG_P53_SIGNALING_PATHWAY | MSigDB lists | KEGG_P53_SIGNALING_PATHWAY | 66 | 20 | 17758 | 2588 |
CCNE2,CASP3,DDB2,CD82,CASP9,TP53,CCNB1,SESN1,TP53I3,CDK1,FAS,TP73,CCND1,SESN3,CCNB3,PTEN,BAX,SERPINB5,STEAP3,CCNB2 |
| 8.279e-04 | -7.10 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | 66 | 20 | 17758 | 2588 |
LTBP1,TCF25,NR4A1,NDRG1,SAT1,ITPR2,SPSB1,LEPR,PARM1,PER2,IRS2,NOV,IGF1R,FAM20C,MITF,BCL6,KLF9,CITED2,HSPA2,DUSP1 |
| 8.281e-04 | -7.10 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | 199 | 46 | 17758 | 2588 |
MYL9,SPRED1,CTHRC1,PCOLCE,PAPSS2,HSPG2,CD63,KCTD12,IL18,FAM198B,SLC1A3,TNS3,ARHGAP42,CTSC,CALD1,COL6A1,ACTA2,RGS5,LOXL1,EPHX1,CYP1B1,CYP26B1,DOCK4,ASPM,TNS1,TANC1,IDH1,ANTXR1,ANKRD29,NFIB,COL12A1,DPYSL3,FUCA1,PGF,TRIM47,GPRC5B,ACVRL1,RND3,WWTR1,MYLK,FAM114A1,OSMR,PLD1,LIFR,CSRP2,CYBRD1 |
| 8.288e-04 | -7.10 | reproductive system development | biological process | GO:0061458 | 404 | 84 | 16441 | 2455 |
GRHL2,LGR4,EPAS1,ST14,LFNG,GATA3,UBE2Q1,PLAC1,BCL2L1,SDC1,PDGFB,CCND1,CTNNB1,LRRC6,DLG1,PLK4,TIPARP,SIRT1,SOD1,AKT1,FZD4,TFAP2C,CCNF,IDH1,SOCS3,PTGS2,HS6ST1,HOXA9,AXL,E2F8,GAB1,ARNT,COL9A3,NKX3-1,CDKN1C,SERPINE2,CTSB,CENPI,BIK,SOX9,TGFBR1,MERTK,SIX4,ICAM1,SGPL1,E2F7,SPP1,DAZAP1,IGF1R,ITGB8,PTEN,CYR61,GATA2,TOX2,CST3,MSH2,BAX,TTPA,TMED2,MDFI,REC8,HES1,ASPM,FNDC3A,EGFR,PRDX4,PITX2,NCOA3,INSR,FGFR2,PRDX3,SPINT2,CTSV,SERPINB5,ARRB1,PKD2,HOXB13,SOX8,OSR1,FZD5,RARG,AHR,FOXA1,EGLN1 |
| 8.293e-04 | -7.09 | skin-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-malignant_melanoma-superficial_spreading | 31 | 12 | 17775 | 2585 |
RB1,NF2,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 8.293e-04 | -7.09 | central_nervous_system-temporal_lobe-glioma-ependymoma | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-ependymoma | 31 | 12 | 17775 | 2585 |
ZFYVE16,HN1L,PTEN,MKRN3,RASA2,SYNE2,TP53,CCBL2,MORF4L2,PIKFYVE,ARHGAP4,MAP3K7 |
| 8.313e-04 | -7.09 | TNFRSF1A (tumor necrosis factor receptor superfamily, member 1A) | protein interactions | 7132 | 106 | 30 | 16036 | 2547 |
ADAM17,BAG4,RHOA,RIPK2,RALBP1,TRAF2,SHARPIN,PIK3R1,EZR,CBL,EGFR,SH3KBP1,OPTN,BCL10,FAS,FYN,CASP7,JAK1,CNTRL,PRDX3,MADD,STAT1,DAPK1,PIK3CA,TRPC1,ERAP1,DAB2IP,PPP1CA,MAP3K7,SYK |
| 8.377e-04 | -7.08 | TIAN_TNF_SIGNALING_VIA_NFKB | MSigDB lists | TIAN_TNF_SIGNALING_VIA_NFKB | 27 | 11 | 17758 | 2588 |
PTGS2,CTGF,NFKBIE,TNIP1,PLK2,ZFP36,NFKBIA,SDC4,NFKB2,IRF1,CD83 |
| 8.377e-04 | -7.08 | CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | MSigDB lists | CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | 27 | 11 | 17758 | 2588 |
MX1,H1F0,HOXA9,ARL4C,BCL6,SELL,CR2,TCF7,FHL1,NOTCH3,GFI1 |
| 8.396e-04 | -7.08 | Golgi cisterna membrane | cellular component | GO:0032580 | 75 | 22 | 17570 | 2579 |
B3GALT6,CHSY3,MOB4,NAGPA,SORT1,GOLIM4,B4GALT4,BCAP31,NCS1,CHPF,GALNT3,NUCB1,INPP5E,FUT2,FUT8,CSGALNACT1,FUT1,ARAP1,CANT1,B4GALT3,ST3GAL1,TMED2 |
| 8.402e-04 | -7.08 | lipid metabolic process | biological process | GO:0006629 | 1158 | 211 | 16441 | 2455 |
ACACB,UGT8,AGRN,HSPG2,TMEM86B,CPT2,PNPLA2,HEXB,EPHX4,PHOSPHO1,TEX2,NANS,CDIPT,PLA2G16,SDC1,PIGL,ECI1,HELZ2,INPP5E,CYP1A1,CTGF,GRHL1,CYP2S1,IMPAD1,ALDH1A3,DDHD2,RDH14,SLC44A1,SERINC2,PIK3CA,ABCA2,AKR1B1,PPP1CA,PIK3CD,ACOX2,TECR,TIPARP,CERS2,CYP1B1,ACBD3,SLC35C1,PRKAR2B,SLC17A5,IDH1,CYP4F3,POR,SLC44A3,SGPP1,KDSR,PLCH1,PI4K2B,PLCG1,MID1IP1,AGPAT2,GDE1,DOLPP1,ADIPOR1,PIK3C2B,GLA,CHPT1,PRKAA2,FAM213B,INPPL1,CYP2J2,TMEM55B,ELOVL7,PRKAA1,ASAH1,ISYNA1,B4GALT4,DHRS3,PGAP1,B4GALNT1,OCRL,BDH1,SORL1,PIKFYVE,FAR2,ACAD8,NCEH1,PLCB2,ALDH3A2,ABCC1,CYP26B1,PIGC,GFPT1,FADS2,PQLC3,LPGAT1,FHL2,PIP4K2C,NPC2,NPHP3,PCTP,GOLT1A,SPTLC2,FECH,MAPKAPK2,NAAA,PRKAG2,UAP1,FA2H,FAAH,PLPP3,DGAT2,PITPNA,SAMD8,CTSA,PLD1,ALG2,APOL2,PLA2G4A,MTM1,INPP5D,ETNK1,P2RX7,MGST2,LPIN3,PRKACA,CYP39A1,CYP26A1,PER2,CDS1,APLP2,PLCG2,FABP6,ACSL4,LGMN,SULT2B1,FAR1,NAGA,GM2A,GPX4,SIRT1,SOAT1,AGPS,CYB5R2,ALDH3B1,PTGS2,ALDH5A1,PAFAH1B3,ACAD10,ABHD12,PEX2,INPP4B,PNPLA6,PPP1CB,SLC27A1,CYP2U1,SLC27A3,ST3GAL1,LTA4H,CNEP1R1,ABCA1,KDELC2,CMAS,CDS2,SCD5,SDC4,GNE,PLD2,CRABP2,PLPPR4,LBR,PNPLA5,SGPL1,ADORA1,OXCT1,SLC27A6,ITGB8,ARSG,PTEN,A4GALT,ALG13,GPC3,FDXR,BAX,ATP8B1,ECI2,SLC44A2,HMGCL,ABCD1,TTPA,SYK,SLC35A1,MYO5A,NCOA2,PCCB,PLSCR1,WNT10B,PLAUR,PIK3R1,ELOVL3,PPARA,ARSK,RNPEP,CPTP,LEPR,DGKE,GPLD1,LDLRAP1,ACADSB,DHRS2,DBI,PLA2G15,GLB1,ACADM,ARSB,PTGES,ACOT7,ABCG1 |
| 8.425e-04 | -7.08 | ovary-carcinoma-serous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-serous_carcinoma | 11219 | 1703 | 17775 | 2585 |
HECA,FAM160B1,IBTK,GRIK2,AK7,HEXB,RET,CCNO,TRAPPC8,BAIAP3,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,SLC35E4,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,ATP13A3,DNM2,TMEM37,RNF26,TIAM1,IL10RB,CPE,TIPARP,MGAT5,NEK4,FBXL16,DSTN,CDA,TMEM98,KDELR3,PRKAR2B,PNKD,ABR,LCP1,ENPP1,PLCG1,MPRIP,ATP7B,CELF5,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,RNASEL,STARD13,HSPB1,ANXA11,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,FAM21C,RABGGTA,MARCH8,TFAP4,FLII,ZCCHC17,FRY,MEGF8,FLRT3,FBXO7,RANBP1,FBXL14,MAP3K9,CADPS2,USP1,USP38,FAM84B,ALPK1,CNGA1,PANX2,MAPK7,MOXD1,MYLIP,DGKG,NUP85,PHKG2,TTLL1,MCCC2,HPS3,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,SFXN5,PSMA4,GNA11,MAGED2,CACHD1,FNTA,SLC4A4,ETS2,RAET1L,CLMN,OSCP1,GDF11,TMEM159,RUSC1,ADAMTS16,DMPK,DOCK9,WDR63,NQO1,LFNG,CD82,RHBDL3,GRK6,MGST2,FAM91A1,MOCS1,KIAA1147,MUC16,ST5,CDH1,XYLT2,ENPP5,RASGEF1A,DLG3,ZNF365,ETV4,MYT1,TMEM200B,MX1,SNX8,COL6A2,ERMP1,C6orf1,RIPK2,PFKFB2,AGPS,VPS4B,HTATIP2,SYP,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,EBF2,GIGYF1,SPIN3,PDLIM3,CCNB3,SHROOM3,CDK19,WFS1,AXL,PNPLA6,FAM149A,MAPK12,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,TRAF2,BIK,HABP4,CCM2,BTN3A1,ZNF219,SLC25A43,NFAT5,BEX2,CTNNBIP1,DIRAS3,ZFX,IGSF9,KNDC1,GPC3,MGAT4A,TMEM62,CST3,TUBGCP6,FAM20B,KLC3,FAM102A,RAG1,CASD1,MED22,PARP9,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,CXorf57,AK4,PGBD1,RAB3IP,C4orf27,CNTNAP1,PROM1,LDLRAP1,PLOD2,SYT7,SLC35B3,FAM3C,PLA2G15,PPM1H,FBXO44,ITGAV,OSR1,PHC1,TLL2,TMEM131,CCNI,TNK1,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,NTN4,SCARA3,PLK1,KRT80,PTPN18,MARK1,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,CCBL2,CKAP2L,NKAIN1,SESN1,DZIP1L,KDM4D,TRIM9,TNS4,PLEKHG6,PI4K2B,TRAM2,KLF12,TXNRD3NB,KLF11,KPNA2,TTC39C,TC2N,HS6ST3,RRAGD,RMND5A,PARP12,RUNX2,USH1C,HJURP,RASA2,PSMD7,ADCK5,HES2,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,ICAM5,PIM1,WNT3A,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,BCL2L13,CDK5R1,PRX,NMT2,C18orf8,RASGRP2,COL13A1,OTUD6B,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CDAN1,USP43,RAD21,TP53,RHPN2,P2RX7,BAHD1,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,TACC2,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,ACO1,DAG1,ATP13A2,PTGS2,TAPBP,IDE,PTPRJ,PAFAH1B3,ABHD12,RBL1,STK38,MAOA,CHMP4B,XRCC3,SYT13,ARHGAP4,FAM134B,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CDH22,CPEB4,TAB3,KLHL13,SCD5,GNAL,MCTP2,HAL,CDCA8,ERCC6L,LBR,PARM1,H1FX,NRP2,CD109,FOXP2,ALPP,CDK16,GTF2F2,FAM63A,IL17RA,TRIM21,SGK1,TSPAN13,ALDH7A1,HMGCL,SYK,FAM134C,ATP2B1,WBP5,DUSP1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,COL7A1,RNPEP,BBS2,DGKE,BCL10,USP6,DDX23,CNOT2,DDAH1,SMTNL2,SCG2,NEIL3,NIPSNAP3A,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,FAM171B,PNISR,LGR4,SSH1,HSPG2,C1orf198,CUL1,PSME1,CAMK1D,NANS,SEPT4,VASH1,PJA2,SLC9A7,ASPHD2,PAK6,TYMP,CYP1A1,ANKS6,ZNF823,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,RAB2B,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,SPRY4,FGD1,RECQL,MRC2,TBC1D1,PRKAA1,APBA1,S100A2,TSPAN7,SH3RF2,MESDC2,CALR,DOPEY2,AIM1,MSH2,DAPK1,PRKG1,ADCK2,C8orf58,CACNA1D,KCTD3,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,GCC2,KCNJ12,PRSS23,CEP89,ADCK3,LPGAT1,DCHS1,PYGL,WHSC1,ATP8B3,ANTXR1,PDE11A,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,PIAS2,MPP2,FAM83D,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,ZBTB34,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,GPR107,REPS2,CAPN12,ST14,THRA,DDIT4L,NDRG1,CERCAM,ATP2C2,FAM78A,FTH1,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPM2A,CD46,APOBEC3B,NOV,CCNA2,ACAP2,TRANK1,RALB,EPHB4,PDE4D,TSPAN1,SULT2B1,ATG4D,DOCK4,COG2,FOXJ2,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ITPR3,ASB13,ALCAM,ATP10D,FZD7,DDOST,POPDC3,ACAD10,CCDC149,TSPAN18,TRIOBP,SLC27A3,COBL,CBX7,MAMDC2,IGFBP6,HAPLN3,EPS8,CBLL1,NES,HERC5,PLD2,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,CKAP5,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,TTPA,MSH6,FARP2,TGIF1,PDGFC,ALDH2,B3GNT2,LONRF3,PAPD7,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,CDK5RAP1,CRTC2,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,ABCB1,ERAP1,WDR62,WDR91,FZD5,ESPL1,DEF6,MELK,FAF2,UGT8,UBE2Q1,VARS2,MPP5,PLAC1,COMMD5,TRIM68,ADPRHL1,ZFYVE16,RAB15,SIPA1L2,CDKL5,CASC4,ARHGEF37,ANKFN1,CEP78,TRPC1,ASH2L,CTTN,MYRIP,BTBD3,STK35,LAMP3,CYP1B1,NLRP4,ASXL1,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,MADD,TDRD7,SH3GLB2,ZNF165,RBM43,CAPN1,PCSK5,ARAP3,PPP1R12A,SERPINE2,ETV5,ABCG2,CALM3,FAM81A,ADAMTSL4,DUSP5,QSOX2,SPP1,TYW3,B3GALNT1,NOXA1,PFKL,OCRL,COL6A1,MTMR10,PRKCI,SRP54,LIMCH1,BRAT1,C10orf54,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNED1,SNX7,ELK3,PODXL2,KIAA1109,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,SOX13,INSR,UAP1,TMEM30A,SPAG7,DCUN1D1,SH3BP4,DONSON,CTSA,C17orf75,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,RARG,DRD1,LMO7,NCKAP5,PAX6,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,MXD1,SAP130,ZNF687,CYP4F11,KIF14,REEP1,ZBTB49,DIXDC1,EPB41L4B,ECE1,UPF3A,EBAG9,PTPRU,GLO1,CD40,TMTC2,FANCE,PDHX,CASP4,HSF4,STAT6,TLE1,SPTBN5,ABCA1,KDELC2,GLIS3,GCLM,ENO2,ARHGEF11,ARHGEF7,SH3D19,SHPRH,SERPINB9,TGFBR1,COL4A5,TRIB2,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,H2AFY,CLIP2,RPGR,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,RUNX3,NDRG3,TCEAL8,LEPR,FOXL1,ARHGAP24,CD8A,CASP7,SWAP70,RAP2C,SPINT2,CSGALNACT1,DTX4,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,DOC2A,ACACB,KLK10,TRIM24,ADD1,AASS,MRPS15,TRIM5,XIAP,CACNA2D2,SMARCAL1,DHX8,FAM102B,NRG2,LGI3,MORF4L2,SYTL4,CNTROB,PHF1,EPDR1,CALM2,DAPK2,TP73,WEE1,PSMD1,TGFBR3,RGS12,AP1M2,PQLC2,DNAH6,RDH14,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,MANF,ODF2L,APOBEC3G,ERAP2,TUBA4A,NWD1,SPEF2,SMARCA2,TNIP1,SERTAD4,SH3BGRL,LOXL2,ICMT,MYOM1,CYP4F3,COL12A1,PGF,TRIM47,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,ARF6,GAB1,ALDH6A1,TMTC3,CYP2J2,SLC36A4,ZNRF3,MERTK,LMNA,RAVER2,ELF3,CD22,PRICKLE4,ZIC5,FAM13B,NEK2,STT3B,NCAM1,C9orf72,EPHX1,NAGPA,SALL4,STAT4,MYBL2,CALCRL,MEST,SPTLC2,RHOB,STK17A,DHX32,PTPRF,NCOA3,MTFMT,HTT,SEMA4D,SETD3,ITPR1,DYSF,AURKA,OSMR,MDH1,ALG2,FBXO27,ARPC2,NDE1,DRP2,ZNF502,TRPC3,SERPINB1,RPS6KA3,CSRP2,XDH,EGLN1,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,WDTC1,RGS20,ETNK1,TESK2,PKP2,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,UHRF1BP1L,RNF220,SP100,DACT1,ACSL4,ARL4D,CDKN2D,SCN3A,RNF169,ENPP4,CAMSAP3,SSH3,LGALS8,FZD4,NRBF2,SYNE2,CDCA2,NUSAP1,PEX5,STX10,TTC12,SLC9A6,WWTR1,SIPA1L1,INPP4B,PLEKHG1,PDXK,GEN1,FARP1,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,PDIA3,GMCL1,ANO9,PKN1,GSTP1,ARHGEF40,ETS1,KCNC4,TSPAN17,SRPX2,TIPRL,ICAM1,PDIA4,NEO1,DTX3L,CXCL16,ANK1,ADD3,SLC27A6,IRAK1,ANKS1B,FAM160A2,ARSG,CTSC,MCF2L,PLEKHF1,ADAM15,MAPK11,AK3,ITM2C,TPCN1,S100A6,HCN3,AMOTL2,POU6F1,CTNNAL1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,PLEKHA7,BLVRA,FAM109A,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,PITX2,GALNT3,KIAA0141,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,CENPE,NUP37,DCBLD1,UNKL,TRIM2,AGRN,FAM199X,EPHA4,CUL4B,FHDC1,NDC80,MCCC1,TP53I11,HDAC6,SDC1,CNTRL,SHC3,MKRN3,DDHD2,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,ZNF462,PCGF5,MCTP1,CD55,ING1,EZR,ERP44,ESYT1,PRKRA,ANLN,FAM212B,IDH1,CLCN2,ZBTB7B,RHEB,VCP,PLEKHB1,IRX3,OPTN,DPYSL3,PLCH1,MFAP3L,TBC1D17,CDCA4,MAP2,DOLPP1,RAB11FIP1,CTNND1,PIK3C2B,TTC9,EPB41L4A,POMT1,PRKAA2,UBASH3B,CNTNAP2,DOCK11,IL18R1,PGAP1,SSX2IP,CORO1B,BMP2,RB1,VASP,IGF1R,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,WDR72,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ANKRD29,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,MAPKAPK2,COQ10A,CSF1,MFSD2A,ITGA7,LTBP2,IFI6,CTBP1,RNF146,FAM45A,AVPI1,KCNAB3,NF2,UPF3B,FOXM1,XYLT1,DGKA,ERBB2,RASGRP3,CCNL1,SLC7A2,LPIN3,C1orf116,CYP26A1,PER2,RAD23A,CDK14,EFR3A,N4BP3,PLCG2,GYS1,SCN2A,FAR1,CTH,CPD,SIRT1,MBP,FIGNL1,CDC20,DNAJC10,DUOX1,ATP1A1,RTN4RL1,PTK7,PSMD3,ADAMTS14,C1orf43,RPL22,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,GOLIM4,TRAPPC10,CD63,MACC1,RUSC2,GABRG2,PSMD10,NKRF,JAG2,DSE,PPP2R3A,SLC9A2,SIRPA,GBX2,CEP97,MAGEE1,BUB1,KLF9,SLC45A3,CAMK2G,TLE6,IGDCC4,DLGAP1,HMMR,MLEC,PSMB4,NR3C1,AMFR,PPARA,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,TMEM50B,BANK1,SERPINA1,FAT4,TWSG1,ZMYND19,TMC5,NETO2,CLIP4,FAM117A,PPP2R3C,PKD2,SPCS3,ACADM,TBC1D4,NDFIP1,DIS3L,GAA,ACVR1,PPP4R4,TTC39B,ATP8A1,FAM129B,KLC2,PPFIBP2,GATA3,PLXNA1,PLA2G16,SLC20A1,ELMOD2,NCS1,CHST2,CTGF,ELMO2,ZFP36,RGS3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,RCAN3,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,PBK,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,MCFD2,SLC25A5,SPNS3,ULK2,ARHGEF26,SGPP1,SFXN1,HLF,SLC25A4,RBM47,PLK2,PTER,TBX1,GNPTAB,DHTKD1,TMEM8B,TANC2,UNC5B,TRAF5,RTN3,LZTS1,DLAT,DDX58,KLF2,MRPL44,CDK17,INPPL1,FRMD4A,HLA-E,CALB2,C6orf106,ISYNA1,NOTCH2,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,PIK3AP1,BDH1,RUNDC3B,OPN3,SORL1,PIKFYVE,RIMS2,TSPAN33,EEF1D,FAM69A,IGSF3,EPB41L5,PMPCB,DDB2,QSOX1,FADS2,B3GNT7,KIAA1841,ZNF84,TBC1D8B,B9D2,MICB,AMER1,PTPRH,ANO6,KCTD20,VEZT,FAM133B,KDM3A,GLT8D2,STX3,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,SERTAD2,DCK,NAB2,SLC4A3,TCEAL4,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PKD1L2,FRMPD3,PLA2G4A,PLEKHG3,SLC2A4,CEP70,ARMCX3,TRIP10,S100A11,NLRX1,BROX,CAST,SUZ12,IQGAP1,RPS6KA1,IRX4,KCTD12,RNF182,CD274,AIFM2,MNS1,GNB2,TMPRSS4,CYHR1,APLP2,FAM46A,CDKN1B,TNPO2,CNNM4,DAB2IP,PHKA2,NR2C1,MYO5B,SLC5A11,SEC23A,TMEM43,CAPN6,TEP1,COX11,SLC11A2,PRKCQ,BCL7B,C15orf39,SP4,PRDM11,NIN,OSBPL2,EPHA10,FYN,ZNF641,JAK1,PPP2R5A,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,KLF5,MLKL,NR3C2,ATMIN,DENND5B,MRPS9,WASF3,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,JRKL,ATP9A,ARL4C,CYB561,APOBEC3H,SPR,PNPLA5,TEAD3,SIX4,LGALS3BP,TMCC3,RND1,SNTA1,FAM111A,PHF7,OXCT1,PTEN,MGAT1,CENPJ,SGK3,PRC1,ATP8B1,SLC44A2,ERCC2,MAP3K7,CNPY3,GFI1,SPRY2,NCOA2,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,ERMAP,TEF,MPP1,PARP4,FURIN,LRRC1,GPLD1,RGS9,NUCB1,CTNS,RCBTB2,AMMECR1,SERPINB5,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,LTBP1,CPT2,CAMKK1,FLYWCH2,TAF6L,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,CAPG,POF1B,ANKRD12,AKR1B1,RAB20,RP2,NFU1,ARNT2,MYH14,TECR,PTPRE,RASGRP1,OLFML2A,ATL1,TDP1,TRIM8,SOD1,RNF165,ROR1,PTGFRN,ADRBK2,STK17B,TCN2,EDNRA,CXXC4,ARHGEF19,NEIL1,FASTKD1,DHRS13,UEVLD,IARS2,ADIPOR1,APBA2,RAP1GAP,PSMC1,PPP2R5D,MIIP,STARD3NL,GRN,LRRFIP2,PEX6,ELOVL7,ASL,ATP6V1E2,SAMD9,PHLPP1,ZNF432,LRRN2,KCNN4,EBF4,FNIP1,KNTC1,RFX5,ACAD8,NCEH1,LRIF1,PARD3B,GYLTL1B,AMDHD1,EGFR,MUM1L1,GLCE,GNAS,BCAR3,XKRX,NUDT16,TSC1,SLC6A6,UTP14C,CGREF1,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,KIF12,PROM2,SLC25A24,SLC2A8,PSME2,ABCG4,MORC4,GMPR,TDRKH,ZMYND10,MICALL2,ARHGEF16,SS18,SETDB2,KHNYN,ZDHHC12,FRYL,SMO,GOT1,RPN2,STEAP3,APIP,PDIA6,F2R,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,GCA,BAG4,TAF5,KREMEN2,OSTM1,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CANT1,AKNA,REEP4,LIFR,CBX4,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,ZNF212,IL17RB,IRF2BPL,MDM1,MLPH,KIAA0319,TRIM3,IQGAP3,SUN2,ADAM17,RAB3B,GCLC,PHLDB3,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MAP1B,HNRNPH2,DHRS2,TADA2B,OTUB2,GLB1,L1CAM,SNPH,ZNF596 |
| 8.444e-04 | -7.08 | regulation of JNK cascade | biological process | GO:0046328 | 158 | 39 | 16441 | 2455 |
PINK1,TAOK2,GRIK2,TRAF2,EPHA4,PKN1,PHLPP1,GSTP1,FGF19,MECOM,TP73,CTGF,IGF1R,DACT1,MAP3K9,DUSP10,DAB2IP,MDFIC,MAP3K7,SYK,DVL2,RASGRP1,MDFI,AKT1,RIPK2,FZD4,ITCH,MAP3K6,MAPK8IP1,FZD7,ANKRD6,MAP3K11,NOD2,KIAA1804,MAP3K5,FZD5,F2RL1,GAB1,HIPK3 |
| 8.453e-04 | -7.08 | PILON_KLF1_TARGETS_UP | MSigDB lists | PILON_KLF1_TARGETS_UP | 484 | 96 | 17758 | 2588 |
GAS2L1,MYL9,CCNC,AGRN,REPS2,TMEM86B,RALBP1,ETNK1,COL18A1,NDRG2,SEPT4,FAM46C,NAPG,TGFBR3,ST5,FRYL,DDHD2,SLC44A1,ACSL4,ACOX2,CTTN,MARCH2,TMEM9,NWD1,CLCN3,COL6A2,CITED4,SLC39A8,PRKAR2B,LOXL2,ZFAND5,ALCAM,IRS2,SLC25A4,DNM1L,MYLK,FAM114A1,PPP1CB,HS3ST3B1,ST3GAL1,ABCA1,DLAT,GCLM,MZT1,CPEB4,DNAJB2,ABCG2,CHAC2,RAB6A,TSPAN7,BMP2K,NRP2,HLA-A,XPR1,ITGA2B,FOXP2,TOP2A,MLPH,IGF1R,RNF128,GPC3,CALD1,SLC44A2,C2orf72,IGFBP2,KNTC1,IGSF3,WBP5,EPB41L5,CRB3,CTNNAL1,EIF5A2,MFSD2B,WHSC1,FBXO9,EIF2AK1,PLS1,SRSF5,SNTB1,BCAR1,FECH,PTPRF,TIMP3,INSR,FGFR2,CSNK1G1,TMEM30A,WDR19,TADA2B,RYK,PKD2,PER3,WDR91,FZD5,RPS6KA3,DMPK |
| 8.462e-04 | -7.07 | ZHANG_TLX_TARGETS_36HR_DN | MSigDB lists | ZHANG_TLX_TARGETS_36HR_DN | 183 | 43 | 17758 | 2588 |
SPC25,UPF3B,DEPDC1,SUZ12,CUL4B,ERI2,ERCC6L,KIF23,CENPN,PSIP1,HMGXB4,FANCI,CKAP5,TOP2A,FAM111A,CCNA2,PRC1,PLK4,BUB1,USP1,EGLN3,SLC12A2,TTPA,NUP85,CCDC88A,SMC4,HMMR,SHMT1,HMGN5,FIGNL1,PIK3R1,NUSAP1,ANLN,KIF11,SKA1,RASA1,PRIM1,SLC4A4,RBL1,TMEM30A,CENPE,SGOL1,NCAPG2 |
| 8.462e-04 | -7.07 | GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP | MSigDB lists | GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP | 183 | 43 | 17758 | 2588 |
PLA2G4A,PRKAA2,RECQL,NLRX1,RALBP1,C5orf30,PBX3,TMEM19,NUP62CL,EXT2,BMP2K,SIRPA,GNS,MZT2A,SLC27A6,LMAN2L,PAPSS1,ACTA2,IL17RA,NCOA2,KDELR1,TMCC2,CLCN3,TNIP1,TCEB2,VAMP3,IFIT3,SKA1,C4orf27,DCP2,TIMP3,SCG2,PRCP,NAT1,TMEM30A,PSMD3,PPP2R4,DBI,RYK,TRIOBP,SPCS3,ZBTB6,CHPT1 |
| 8.523e-04 | -7.07 | skin-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-adnexal_tumour-malignant_adnexal_tumour | 16 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 8.523e-04 | -7.07 | bone-mandible-other-ameloblastoma | COSMIC cancer mutations | bone-mandible-other-ameloblastoma | 16 | 8 | 17775 | 2585 |
CTNNB1,FGFR2,SMO,PIK3CA,TP53,ERBB2,JAK3,EGFR |
| 8.523e-04 | -7.07 | skin-leg-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-leg-adnexal_tumour-malignant_adnexal_tumour | 16 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 8.523e-04 | -7.07 | parietooccipital | COSMIC cancer mutations | parietooccipital | 16 | 8 | 17775 | 2585 |
CDKN2C,CTNNB1,PTEN,MSH2,TP53,IDH1,MSH6,EGFR |
| 8.523e-04 | -7.07 | ameloblastoma | COSMIC cancer mutations | ameloblastoma | 16 | 8 | 17775 | 2585 |
CTNNB1,FGFR2,SMO,PIK3CA,TP53,ERBB2,JAK3,EGFR |
| 8.567e-04 | -7.06 | PDZ | smart domains | SM00228 | 149 | 39 | 9131 | 1455 |
LMO7,FRMPD3,USH1C,ARHGEF11,RHPN2,MPP5,APBA1,SLC9A3R2,PICK1,SNTA1,SIPA1L2,RGS12,RGS3,DLG1,TAX1BP3,DLG3,MAST4,TIAM1,RIMS2,DVL2,CASK,PARD3B,RAPGEF2,SNTB2,MPP1,SCRIB,ERBB2IP,SNTB1,RHPN1,PRX,PDLIM3,GRID2IP,TJP3,SHROOM3,LIMK1,SIPA1L1,MPP2,SHROOM2,APBA2 |
| 8.600e-04 | -7.06 | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN | MSigDB lists | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN | 100 | 27 | 17758 | 2588 |
CCNE2,FBXL16,GRHL2,ZNF395,LGR4,HOXB7,LFNG,C12orf65,ZNRF3,PHLPP1,SSX2IP,RHOB,B3GALNT1,KCTD15,RAB11FIP2,TACC2,RBL1,ZNF367,DAPK1,RHOBTB2,USP1,MAP3K5,DLG3,MPHOSPH9,KCTD3,MSH6,GCNT1 |
| 8.603e-04 | -7.06 | ZHU_CMV_8_HR_UP | MSigDB lists | ZHU_CMV_8_HR_UP | 48 | 16 | 17758 | 2588 |
PLA2G4A,MX1,CD55,B3GNT2,NR4A1,HLA-E,GMPR,BCL7B,PTGS2,SP100,NR4A3,IRF2,TRIM21,IFIT1,LGMN,IFI6 |
| 8.603e-04 | -7.06 | BCAT_GDS748_UP | MSigDB lists | BCAT_GDS748_UP | 48 | 16 | 17758 | 2588 |
C3orf52,CASP9,PKP2,KCTD12,TP53I3,FZD7,DDAH1,SRPX,CA2,FAM3C,AIM1,ABCB1,PDE4D,GAD1,GCNT1,FAH |
| 8.603e-04 | -7.06 | GYORFFY_DOXORUBICIN_RESISTANCE | MSigDB lists | GYORFFY_DOXORUBICIN_RESISTANCE | 48 | 16 | 17758 | 2588 |
TIMP2,AASS,BACE1,PTPRH,CDYL,ZNRF3,SNTB1,EGFR,BMP2,TYMP,AIM1L,FAT4,FAAH,BMP7,ABCB1,NETO2 |
| 8.611e-04 | -7.06 | peptidyl-asparagine modification | biological process | GO:0018196 | 179 | 43 | 16441 | 2455 |
CMAS,TRAPPC10,MAN1A2,GNE,PDIA3,CTSZ,NANS,B4GALT4,CALR,CTSC,MGAT1,ALG13,MGAT4A,FUT8,UBE2J1,RPN2,STT3B,LMAN1,TFG,MGAT5,SLC35A1,PPP6R1,TMED2,GFPT1,SEC23A,MLEC,MGAT4B,COL7A1,SLC17A5,MCFD2,VCP,FUCA1,MAN2A2,UAP1,SERPINA1,DDOST,AREG,DOLPP1,GLB1,CTSA,ALG2,B4GALT3,ST3GAL1 |
| 8.625e-04 | -7.06 | peptidyl-tyrosine phosphorylation | biological process | GO:0018108 | 153 | 38 | 16441 | 2455 |
TNK1,DYRK3,IL15,EPHA4,RET,TESK2,ERBB2,TEC,PDGFB,FLT3,DDR1,MERTK,WEE1,IGF1R,MAP3K9,NPTN,EPHB4,F2R,SYK,RIPK2,TESK1,YES1,ROR1,EPHA1,EGFR,TXK,EPHA10,FYN,INSR,JAK1,FGFR2,AXL,PTK7,KIAA1804,RYK,MAP3K11,JAK3,MELK |
| 8.647e-04 | -7.05 | BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | 16 | 8 | 17758 | 2588 |
QSOX1,CTGF,AGPAT2,PLD1,F2RL1,MAFF,LGALS3BP,IER3 |
| 8.671e-04 | -7.05 | human chr22q13.1 | chromosome location | human chr22q13.1 | 82 | 19 | 26250 | 2805 |
SUN2,APOBEC3D,GCAT,CBX6,KDELR3,APOBEC3H,PDGFB,IFT27,CARD10,HMGXB4,PICK1,RAC2,H1F0,SH3BP1,TRIOBP,NPTXR,TTLL1,CBX7,MAFF |
| 8.672e-04 | -7.05 | FGF signaling pathway | Pathway Interaction DB | fgf_pathway | 47 | 20 | 2227 | 480 |
RUNX2,AKT1,SSH1,PLAUR,RPS6KA1,PIK3R1,CBL,FOS,FGF19,PLCG1,SPP1,CDH1,FGFR2,PIK3CA,STAT1,CTNND1,CTTN,NCAM1,GAB1,SPRY2 |
| 8.672e-04 | -7.05 | RABEPK (Rab9 effector protein with kelch motifs) | protein interactions | 10244 | 9 | 6 | 16036 | 2547 |
ZYX,PRKRA,PIKFYVE,GGA1,POR,TMEM98 |
| 8.672e-04 | -7.05 | CAPNS2 (calpain, small subunit 2) | protein interactions | 84290 | 9 | 6 | 16036 | 2547 |
ACTA2,CAPN2,CAPNS1,GMCL1,CAST,CAPN1 |
| 8.672e-04 | -7.05 | ANKZF1 (ankyrin repeat and zinc finger domain containing 1) | protein interactions | 55139 | 9 | 6 | 16036 | 2547 |
DNAJB11,AURKB,CTTN,CA2,STAT6,VCP |
| 8.680e-04 | -7.05 | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | 194 | 45 | 17758 | 2588 |
OTUD5,SPRED1,LZTFL1,CPEB4,TRAF2,C5orf30,MIER3,UBE2Z,KCTD12,BLCAP,TXNDC9,PSME1,CD274,CCNL1,CHAC2,TNFSF9,FAM46A,PPP1R10,FLRT3,MGAT4A,MITF,FBXO7,TMBIM6,MTMR11,OAS3,LRP11,TIAM1,XKR8,NUB1,CCBL2,RAB3IP,ABR,FZD7,DCP2,CD83,NFIX,ARHGAP35,TMEM50B,SEMA4D,HTT,PTK7,NAT1,TRIOBP,PLOD3,TRAF5 |
| 8.680e-04 | -7.05 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | 194 | 45 | 17758 | 2588 |
IL15RA,PSME2,HLA-E,ASL,TAP1,ETNK1,PSME1,ISYNA1,CMTM6,LGALS3BP,PER2,RABGGTA,TYMP,TNPO2,TRIM21,HLA-C,ZRANB1,WBP4,SMYD5,TUBA4A,CERS2,MX1,SEC23A,B3GNT2,HMGN5,USP18,SH3BGRL,SAT1,NMT2,HLA-B,TAPBP,NCOA3,TMEM50B,ATP1A1,NAT1,FAM3C,NMI,STAT1,FAM117A,IRF7,PPP2R3C,CMPK2,IFIH1,NRBP1,CBX4 |
| 8.680e-04 | -7.05 | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP | 194 | 45 | 17758 | 2588 |
SLC25A24,CCDC109B,GGA1,INPP5D,ARHGEF7,XYLT1,SELL,GMCL1,TXNDC9,TGFBR1,TRMT2B,NOTCH2,TRIB2,DDR1,TIPRL,SGPL1,CD22,FRYL,AIM1,PIK3CD,TPCN1,GCA,SMARCA2,ARAP2,MMD,CXorf57,KCTD20,CR2,C4orf27,SGPP1,CD83,BCL10,PRIM1,ENDOD1,BTG1,CDK19,UTP14C,STAT6,ITPR1,DTX4,PIK3C2B,NUP37,NR3C2,PKIA,PHC1 |
| 8.680e-04 | -7.05 | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDM_UP | 194 | 45 | 17758 | 2588 |
RUNX2,IL15,GCAT,PSME2,PHOSPHO1,CHAC2,CHPF,CNTRL,CTSC,LHX6,MITF,CDKN1B,SNX16,RFX5,TIPARP,MCCC2,CASK,HMGN5,RFK,MPP1,VAMP3,FURIN,PDK3,FNDC3A,TANC1,ASB13,BBS2,LCP1,ARF4,NMT2,ENDOD1,HLA-B,PI4K2B,RND3,PIAS2,MPP2,HDAC1,SP6,ITGAV,GLA,ATP1B3,IFIH1,ANXA11,IRF1,HS6ST3 |
| 8.680e-04 | -7.05 | V$RP58_01 | MSigDB lists | V$RP58_01 | 194 | 45 | 17758 | 2588 |
LTBP1,PCOLCE,ACVR1,SORBS1,NUAK1,TSC22D3,RAB6A,GPSM2,PRKACA,PDGFB,SPTB,SRPX2,C1orf116,TFAP4,FOXP2,DAPK1,ANKRD12,DLG3,NTN1,CNPY3,BTBD3,RIMS2,ADAMTS2,PCDH1,NR3C1,PRICKLE1,COL7A1,TNS1,LRRC1,TP53INP2,GLT8D2,ABR,XKRX,LRRC42,ONECUT1,PTK7,SH3GLB2,NXPH4,GRIN2D,KLF5,NR4A2,SHOX2,NRGN,RARG,COL16A1 |
| 8.680e-04 | -7.05 | GSE22886_NAIVE_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NKCELL_DN | 194 | 45 | 17758 | 2588 |
LAMP1,ARHGEF3,CDK17,PPP1R12A,SSH1,NLRX1,ZCCHC24,ACTR8,DCAF7,MCTP2,BARD1,IL18R1,TIPRL,NFAT5,ZFYVE16,ZNF432,FRYL,TMEM62,PHTF1,PLCG2,FAM13B,HLA-C,NCAM1,PTPRE,NCOA2,ARAP2,TACC1,ITCH,CDYL,FURIN,ATP1B1,YES1,LDB2,PCTP,ATP10D,C18orf8,GALNT3,FAM64A,UEVLD,HTT,WIPI1,RAB11FIP1,ZNF701,RNF146,JARID2 |
| 8.680e-04 | -7.05 | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_UP | MSigDB lists | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_UP | 194 | 45 | 17758 | 2588 |
EPAS1,CD63,SEC61G,PSME2,HLA-E,TAP1,NDUFA4,PSME1,COX6C,PHLDA1,HLA-A,TIMP1,CES2,ZDHHC13,TRIM21,HLA-C,IL10RB,EEF1D,CKS2,SOD1,MLEC,B3GNT2,MRPS33,STAT4,BCL9,SPA17,BTN3A2,EMP3,CAPNS1,MRPS18A,IFIT3,ANTXR1,HLA-B,TMEM50B,C19orf66,ZFP30,PEX2,NMI,STAT1,IFIH1,MYL12B,COBL,IFI6,JARID2,IRF1 |
| 8.680e-04 | -7.05 | GSE8515_IL1_VS_IL6_4H_STIM_)MAC_UP | MSigDB lists | GSE8515_IL1_VS_IL6_4H_STIM_)MAC_UP | 194 | 45 | 17758 | 2588 |
TNK1,TRIP10,SEC61G,SERPINB9,APOO,SDC4,P2RX7,EGR3,SNN,CENPN,TNFSF9,PGAP1,CHST2,ICAM1,IER3,BTG3,FRY,PPP1R10,FAM189A1,SLC16A6,CD70,RP2,NFKB2,RASGRP1,PPIF,SLC37A1,RIPK2,TNIP1,SEPT6,STAT4,NFE2L1,PTGER4,SPAG1,CD83,BCL10,BTG1,PTGS2,RAP2C,NFKBIA,SLC2A6,KLF5,KPNA2,MAFF,EHD1,DOCK9 |
| 8.699e-04 | -7.05 | negative regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001237 | 93 | 26 | 16441 | 2455 |
GCLM,ACVR1,LGALS3,AKT1,ITGA6,GCLC,STRADB,TGFBR1,BCL2L1,PELI3,GSTP1,ICAM1,LMNA,FYN,SCG2,HTT,DAPK1,NRG1,ITGAV,CTTN,UNC5B,MAPK7,FAIM,IFI6,TMBIM1,ZC3HC1 |
| 8.705e-04 | -7.05 | Rho_GTPase_activation_prot | interpro domains | IPR008936 | 90 | 25 | 18293 | 2672 |
ARHGAP11A,ARAP3,ARAP2,DEPDC1,IQGAP1,RALBP1,RASA2,PIK3R1,RACGAP1,PLXNA1,RASA1,ABR,SYDE2,ARHGAP35,ARHGAP24,ARHGAP42,SH3BP1,OCRL,FAM13B,ARAP1,DAB2IP,PLXND1,IQGAP3,ARHGAP4,STARD13 |
| 8.750e-04 | -7.04 | - | gene3d domains | 1.20.80.10 | 49 | 17 | 9988 | 1574 |
EPB41L5,ACBD5,FARP1,FRMD4A,NF2,FRMD6,ACBD3,EZR,FRMD4B,PLEKHH2,DBI,ECI2,EPB41L4B,EPB41L4A,TLN2,MYLIP,FARP2 |
| 8.755e-04 | -7.04 | MET (MET proto-oncogene, receptor tyrosine kinase) | protein interactions | 4233 | 57 | 19 | 16036 | 2547 |
CASP3,INPPL1,INPP5D,PIK3R1,FBXO6,CBL,SPSB1,PCBP1,RANBP9,EGFR,SH3KBP1,FAS,PLCG1,PTPRJ,CDH1,CTNNB1,LRIG1,CTTN,GAB1 |
| 8.777e-04 | -7.04 | AGC_KINASE_CTER | prosite domains | PS51285 | 55 | 18 | 11866 | 1802 |
AKT1,CIT,RPS6KA1,PRKCQ,GRK6,PKN1,PRKACA,ADRBK2,RPS6KA2,ADRBK1,STK38,PRKG1,SGK3,PRKCI,SGK1,MAST4,RPS6KA3,DMPK |
| 8.783e-04 | -7.04 | Ez/rad/moesin-like | interpro domains | IPR000798 | 16 | 8 | 18293 | 2672 |
EPB41L5,FARP1,NF2,EZR,EPB41L4B,EPB41L4A,MYLIP,FARP2 |
| 8.793e-04 | -7.04 | acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_B_cell_leukaemia | 3979 | 641 | 17775 | 2585 |
HECA,TRIM24,ADD1,IL15RA,FAM160B1,AASS,CACNA2D2,XIAP,TRAPPC8,LYNX1,BAIAP3,SNX9,CA8,FAM46C,CMTM6,LTBP3,EPDR1,CDKN2C,DAPK2,PQLC2,ARHGAP42,RGS12,TGFBR3,DNAH6,PAQR5,ATP13A3,DNM2,PIK3CD,TMEM37,CPE,TIPARP,ERAP2,DNAAF3,PRKAR2B,LOXL2,PPP1R14C,RNF19B,MYOM1,PNKD,COL12A1,ENPP1,DNM1L,ATP7B,TRAF3IP1,NOD2,MRPS28,STARD13,GAB1,SCN5A,SOX9,ELF3,ATG4A,FAM189A1,CD22,MEGF8,MAP3K9,SLAIN2,CADPS2,STT3B,NCAM1,NUP85,HPS3,SLC37A1,STAT4,FHL2,MYBL2,ELK1,NPHP3,DPYSL4,DCP2,PTPRF,CACHD1,SLC4A4,MTFMT,HTT,SETD3,ITPR1,FBXO27,TRPC3,XDH,DOCK9,ARHGAP11A,MTM1,TPRN,GRHL2,TMSB15A,ACTR8,RHBDL3,PKP2,PRSS22,ZNF385B,CDS1,MUC16,RNF220,ARL4D,MYT1,TMCC2,SSH3,LGALS8,NRBF2,SEPT6,SYNE2,HTATIP2,CDCA2,TANC1,ZNF618,EBF2,PDLIM3,SHROOM3,TTC12,SIPA1L1,WWTR1,INPP4B,MAPK12,TTC8,TAOK2,FAM189A2,PLEKHJ1,ANO9,TSPAN17,BEX2,DTX3L,ZFX,ADD3,ITGB8,SLC27A6,ANKS1B,KNDC1,KCNK5,CALD1,ALG13,ECI2,WWP1,ZNF230,CASD1,HCN3,ADAMTS2,FMN1,PIK3R1,GRIN1,PLEKHA7,AK4,SNTB1,CNTNAP1,GALNT3,PLOD2,CCDC6,NR1D2,ZFP30,FAM3C,PPM1H,FBXO44,CENPE,USF2,DCBLD1,ACOT7,FOXA1,PHC1,TLL2,TMEM131,UNKL,AGRN,EPAS1,EPHA4,CUL4B,FHDC1,MCCC1,TEX2,ITPR2,SPTB,PLS3,TFAP2E,NUP210,CTNNB1,NPNT,SHC3,IL6ST,ELF5,MITF,TMEM143,ABCA2,NTN4,TNFRSF18,ANO4,TLN2,NEB,ZNF462,THRB,KRT80,MCTP1,MARK1,CELSR2,CCBL2,KLK6,FAM212B,ANLN,IDH1,SESN1,PLEKHB1,VCP,DZIP1L,DPYSL3,PLEKHG6,MFAP3L,TRAM2,TBC1D17,CDCA4,KLF12,MAP2,KLF11,PIEZO1,TTC39C,EPB41L4A,GLCCI1,HS6ST3,RRAGD,UBASH3B,CNTNAP2,NCKAP1,PGAP1,MYO5C,B4GALNT1,TNS3,RB1,IGF1R,GATA2,FRAS1,KIF13B,MDFIC,NTN1,PLCB2,ALDH3A2,DPYSL5,CHSY3,PLEKHA6,BCL2L13,CDK5R1,MAPKAPK2,PVRL2,MFSD2A,PHLPP2,P4HA3,NLRC5,PLD1,ATP1B3,SEMA3A,RAD21,USP43,NF2,TMX4,TP53,CCDC68,ERBB2,PER2,CDK14,TTC21B,EFR3A,TACC2,PLCG2,GYS1,GLB1L2,ESPN,NOTCH3,EGLN3,SULF2,CPD,PPIF,TMTC1,AKT1,DUOX1,IDE,PTPRJ,ADAMTS14,MAOA,EFNA5,SYT13,ARHGAP4,RPL22,LTA4H,AIFM3,NDST3,CMTM4,ZC3HC1,MAN2B2,BIN1,CDH22,CPEB4,MACC1,DAP,GNAL,MCTP2,HAL,CDCA8,GABRG2,SLC9A2,NRP2,CD109,CDK16,ALPP,TFAP2A,GTF2F2,FAM63A,SYK,ATP2B1,DLGAP1,FBLN5,IFITM3,NR3C1,PRICKLE1,DPP9,MAML2,COL7A1,BCAR1,USP6,BANK1,FAT4,NEIL3,NAT1,SH3BGRL2,ACADM,GOLGB1,FAM171B,ACVR1,PNISR,PPP4R4,LGR4,VANGL1,TSC22D3,ATP8A1,CUL1,PDGFRL,PLXNA1,VASH1,SLC20A1,PICK1,PAK6,CTGF,IQCE,PIK3CA,IRF2,ATRNL1,METAP2,SPATA18,ACVR1C,HSPA12A,NBPF3,KIF13A,TNS1,CCNF,LDB2,SLC25A5,ARHGEF26,SGPP1,AHRR,GDE1,NKD1,BMP1,PRDM5,UNC5B,CDK17,MRC2,FRMD4A,TBC1D1,DGKQ,PRKAA1,AKAP17A,NOTCH2,SLC1A3,APBA1,PDXDC1,KIAA1161,DOPEY2,RALGPS2,SLC16A6,BDH1,MSH2,RUNDC3B,PRKG1,SORL1,CACNA1D,RIMS2,TRAK2,DNAI1,KCNJ12,QSOX1,B3GNT7,MFI2,AMER1,DCHS1,WHSC1,KDM3A,NFIB,RASA1,STX3,MMP15,DGKH,NT5C2,PRKAG2,DCK,ARAP1,MPP2,CABIN1,PER3,PLIN3,HOOK1,IFIH1,PKD1L2,FRMPD3,PLA2G4A,PLEKHG3,SLC2A4,CAPN12,DLGAP5,ST14,SUZ12,CERCAM,TMEM170B,FLT3,ART5,CYP39A1,EPM2A,NOV,RALB,CNNM4,DAB2IP,IFIT1,RNASEH2A,LGMN,FLOT2,TBC1D10B,MYO5B,SLC5A11,CAPN6,TMEM43,DRAP1,CYB5R2,TEP1,UTRN,PRKCQ,ATP1B1,CBL,ITPR3,PRDM11,POPDC3,JAK1,KIAA1804,STAT1,NRG1,MLKL,B4GALT3,NR3C2,COBL,MAMDC2,DENND5B,OTUD5,WASF3,SLC16A14,ATP9A,SLC41A1,CCNJL,PBX3,NES,GPR180,DNAH3,HLA-A,TMCC3,CKAP5,SCML1,FAM111A,PHF7,OXCT1,PTEN,DRAM1,PRC1,CD9,SLC44A2,CNOT6L,GFI1,MSH6,PDGFC,ARHGEF28,LONRF3,PAPD7,DENND1B,PARP4,DIAPH2,FBXO9,UBAC1,LRRC1,CRTC2,FGFR2,SLC25A40,ABCB1,SERPINB5,ARSB,CPEB2,MELK,USP16,JARID2,ESYT2,EXPH5,LTBP1,UGT8,FAF2,VARS2,KIF2C,DNER,CACNB4,TMC1,SH3KBP1,CHPF,HTR1D,NKAIN3,ARHGEF10L,SIPA1L2,RAB15,CDKL5,CASC4,DPYSL2,PHTF1,DLG1,ANKRD12,TRPC1,RP2,NFU1,CTTN,MYH14,ARNT2,MYRIP,ASXL1,RGAG1,ROR1,PTGFRN,ADRBK2,LRRC42,NEIL1,DHRS13,KCNK1,MADD,APBA2,CD99,GRN,PPP1R12A,ELOVL7,PHLPP1,ADAMTSL4,LYSMD4,CES2,FAM20C,COL6A1,PRKCI,EBF4,LIMCH1,C10orf54,KNTC1,ACAD8,SLC12A2,ALS2CL,PDE5A,KIAA1109,EGFR,BCAR3,TSC1,ONECUT1,SLC6A6,NXPH4,SHROOM2,JAK3,AFAP1,RARG,SNX30,PROM2,GAS2L1,LMO7,NCKAP5,PDIA5,COL18A1,IL27RA,SAP130,LRRC45,ZNF687,CYP4F11,EPB41L4B,PDIA6,SEPHS1,GCA,RFK,PTPRU,BTBD19,TMTC2,DOCK5,ARHGAP35,TLE1,VSIG10,SPTBN5,PLXND1,LNP1,LIFR,ABCA1,CBX4,GLIS3,FBLIM1,LRP4,MIER3,COL4A5,POMGNT1,HDAC9,SNX13,MLPH,BMP7,TOX2,GALNS,KANK2,IQGAP3,C12orf75,RPGR,MYO5A,PGM1,SUN2,WNT10B,ASPM,DEPDC4,GCLC,RC3H2,OGDHL,TTC7A,FOXL1,MAP1B,KLHL2,CD8A,SWAP70,SPINT2,CSGALNACT1,OTUB2,UACA,ARRB1,GRAMD1C,ZMIZ1,ATP6V1C1,L1CAM,ABCG1 |
| 8.793e-04 | -7.04 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | 3979 | 641 | 17775 | 2585 |
HECA,TRIM24,ADD1,IL15RA,FAM160B1,AASS,CACNA2D2,XIAP,TRAPPC8,LYNX1,BAIAP3,SNX9,CA8,FAM46C,CMTM6,LTBP3,EPDR1,CDKN2C,DAPK2,PQLC2,ARHGAP42,RGS12,TGFBR3,DNAH6,PAQR5,ATP13A3,DNM2,PIK3CD,TMEM37,CPE,TIPARP,ERAP2,DNAAF3,PRKAR2B,LOXL2,PPP1R14C,RNF19B,MYOM1,PNKD,COL12A1,ENPP1,DNM1L,ATP7B,TRAF3IP1,NOD2,MRPS28,STARD13,GAB1,SCN5A,SOX9,ELF3,ATG4A,FAM189A1,CD22,MEGF8,MAP3K9,SLAIN2,CADPS2,STT3B,NCAM1,NUP85,HPS3,SLC37A1,STAT4,FHL2,MYBL2,ELK1,NPHP3,DPYSL4,DCP2,PTPRF,CACHD1,SLC4A4,MTFMT,HTT,SETD3,ITPR1,FBXO27,TRPC3,XDH,DOCK9,ARHGAP11A,MTM1,TPRN,GRHL2,TMSB15A,ACTR8,RHBDL3,PKP2,PRSS22,ZNF385B,CDS1,MUC16,RNF220,ARL4D,MYT1,TMCC2,SSH3,LGALS8,NRBF2,SEPT6,SYNE2,HTATIP2,CDCA2,TANC1,ZNF618,EBF2,PDLIM3,SHROOM3,TTC12,SIPA1L1,WWTR1,INPP4B,MAPK12,TTC8,TAOK2,FAM189A2,PLEKHJ1,ANO9,TSPAN17,BEX2,DTX3L,ZFX,ADD3,ITGB8,SLC27A6,ANKS1B,KNDC1,KCNK5,CALD1,ALG13,ECI2,WWP1,ZNF230,CASD1,HCN3,ADAMTS2,FMN1,PIK3R1,GRIN1,PLEKHA7,AK4,SNTB1,CNTNAP1,GALNT3,PLOD2,CCDC6,NR1D2,ZFP30,FAM3C,PPM1H,FBXO44,CENPE,USF2,DCBLD1,ACOT7,FOXA1,PHC1,TLL2,TMEM131,UNKL,AGRN,EPAS1,EPHA4,CUL4B,FHDC1,MCCC1,TEX2,ITPR2,SPTB,PLS3,TFAP2E,NUP210,CTNNB1,NPNT,SHC3,IL6ST,ELF5,MITF,TMEM143,ABCA2,NTN4,TNFRSF18,ANO4,TLN2,NEB,ZNF462,THRB,KRT80,MCTP1,MARK1,CELSR2,CCBL2,KLK6,FAM212B,ANLN,IDH1,SESN1,PLEKHB1,VCP,DZIP1L,DPYSL3,PLEKHG6,MFAP3L,TRAM2,TBC1D17,CDCA4,KLF12,MAP2,KLF11,PIEZO1,TTC39C,EPB41L4A,GLCCI1,HS6ST3,RRAGD,UBASH3B,CNTNAP2,NCKAP1,PGAP1,MYO5C,B4GALNT1,TNS3,RB1,IGF1R,GATA2,FRAS1,KIF13B,MDFIC,NTN1,PLCB2,ALDH3A2,DPYSL5,CHSY3,PLEKHA6,BCL2L13,CDK5R1,MAPKAPK2,PVRL2,MFSD2A,PHLPP2,P4HA3,NLRC5,PLD1,ATP1B3,SEMA3A,RAD21,USP43,NF2,TMX4,TP53,CCDC68,ERBB2,PER2,CDK14,TTC21B,EFR3A,TACC2,PLCG2,GYS1,GLB1L2,ESPN,NOTCH3,EGLN3,SULF2,CPD,PPIF,TMTC1,AKT1,DUOX1,IDE,PTPRJ,ADAMTS14,MAOA,EFNA5,SYT13,ARHGAP4,RPL22,LTA4H,AIFM3,NDST3,CMTM4,ZC3HC1,MAN2B2,BIN1,CDH22,CPEB4,MACC1,DAP,GNAL,MCTP2,HAL,CDCA8,GABRG2,SLC9A2,NRP2,CD109,CDK16,ALPP,TFAP2A,GTF2F2,FAM63A,SYK,ATP2B1,DLGAP1,FBLN5,IFITM3,NR3C1,PRICKLE1,DPP9,MAML2,COL7A1,BCAR1,USP6,BANK1,FAT4,NEIL3,NAT1,SH3BGRL2,ACADM,GOLGB1,FAM171B,ACVR1,PNISR,PPP4R4,LGR4,VANGL1,TSC22D3,ATP8A1,CUL1,PDGFRL,PLXNA1,VASH1,SLC20A1,PICK1,PAK6,CTGF,IQCE,PIK3CA,IRF2,ATRNL1,METAP2,SPATA18,ACVR1C,HSPA12A,NBPF3,KIF13A,TNS1,CCNF,LDB2,SLC25A5,ARHGEF26,SGPP1,AHRR,GDE1,NKD1,BMP1,PRDM5,UNC5B,CDK17,MRC2,FRMD4A,TBC1D1,DGKQ,PRKAA1,AKAP17A,NOTCH2,SLC1A3,APBA1,PDXDC1,KIAA1161,DOPEY2,RALGPS2,SLC16A6,BDH1,MSH2,RUNDC3B,PRKG1,SORL1,CACNA1D,RIMS2,TRAK2,DNAI1,KCNJ12,QSOX1,B3GNT7,MFI2,AMER1,DCHS1,WHSC1,KDM3A,NFIB,RASA1,STX3,MMP15,DGKH,NT5C2,PRKAG2,DCK,ARAP1,MPP2,CABIN1,PER3,PLIN3,HOOK1,IFIH1,PKD1L2,FRMPD3,PLA2G4A,PLEKHG3,SLC2A4,CAPN12,DLGAP5,ST14,SUZ12,CERCAM,TMEM170B,FLT3,ART5,CYP39A1,EPM2A,NOV,RALB,CNNM4,DAB2IP,IFIT1,RNASEH2A,LGMN,FLOT2,TBC1D10B,MYO5B,SLC5A11,CAPN6,TMEM43,DRAP1,CYB5R2,TEP1,UTRN,PRKCQ,ATP1B1,CBL,ITPR3,PRDM11,POPDC3,JAK1,KIAA1804,STAT1,NRG1,MLKL,B4GALT3,NR3C2,COBL,MAMDC2,DENND5B,OTUD5,WASF3,SLC16A14,ATP9A,SLC41A1,CCNJL,PBX3,NES,GPR180,DNAH3,HLA-A,TMCC3,CKAP5,SCML1,FAM111A,PHF7,OXCT1,PTEN,DRAM1,PRC1,CD9,SLC44A2,CNOT6L,GFI1,MSH6,PDGFC,ARHGEF28,LONRF3,PAPD7,DENND1B,PARP4,DIAPH2,FBXO9,UBAC1,LRRC1,CRTC2,FGFR2,SLC25A40,ABCB1,SERPINB5,ARSB,CPEB2,MELK,USP16,JARID2,ESYT2,EXPH5,LTBP1,UGT8,FAF2,VARS2,KIF2C,DNER,CACNB4,TMC1,SH3KBP1,CHPF,HTR1D,NKAIN3,ARHGEF10L,SIPA1L2,RAB15,CDKL5,CASC4,DPYSL2,PHTF1,DLG1,ANKRD12,TRPC1,RP2,NFU1,CTTN,MYH14,ARNT2,MYRIP,ASXL1,RGAG1,ROR1,PTGFRN,ADRBK2,LRRC42,NEIL1,DHRS13,KCNK1,MADD,APBA2,CD99,GRN,PPP1R12A,ELOVL7,PHLPP1,ADAMTSL4,LYSMD4,CES2,FAM20C,COL6A1,PRKCI,EBF4,LIMCH1,C10orf54,KNTC1,ACAD8,SLC12A2,ALS2CL,PDE5A,KIAA1109,EGFR,BCAR3,TSC1,ONECUT1,SLC6A6,NXPH4,SHROOM2,JAK3,AFAP1,RARG,SNX30,PROM2,GAS2L1,LMO7,NCKAP5,PDIA5,COL18A1,IL27RA,SAP130,LRRC45,ZNF687,CYP4F11,EPB41L4B,PDIA6,SEPHS1,GCA,RFK,PTPRU,BTBD19,TMTC2,DOCK5,ARHGAP35,TLE1,VSIG10,SPTBN5,PLXND1,LNP1,LIFR,ABCA1,CBX4,GLIS3,FBLIM1,LRP4,MIER3,COL4A5,POMGNT1,HDAC9,SNX13,MLPH,BMP7,TOX2,GALNS,KANK2,IQGAP3,C12orf75,RPGR,MYO5A,PGM1,SUN2,WNT10B,ASPM,DEPDC4,GCLC,RC3H2,OGDHL,TTC7A,FOXL1,MAP1B,KLHL2,CD8A,SWAP70,SPINT2,CSGALNACT1,OTUB2,UACA,ARRB1,GRAMD1C,ZMIZ1,ATP6V1C1,L1CAM,ABCG1 |
| 8.824e-04 | -7.03 | DER_IFN_GAMMA_RESPONSE_UP | MSigDB lists | DER_IFN_GAMMA_RESPONSE_UP | 71 | 21 | 17758 | 2588 |
ELK4,PLSCR1,IL15RA,HLA-E,TAP1,PSME1,IFIT3,PHLDA1,HLA-A,ICAM1,FAS,ATP6V0B,BTG1,PLOD2,NMI,STAT1,VAT1,TRIM21,HLA-C,COL16A1,IRF1 |
| 8.824e-04 | -7.03 | V$LXR_Q3 | MSigDB lists | V$LXR_Q3 | 71 | 21 | 17758 | 2588 |
CCNI,ADAM17,SLC2A4,NUAK1,MAPKAPK3,LYRM1,BLVRB,HPCAL4,NKAIN3,NFKBIA,MITF,SGK1,NRG1,ETV4,SPRY2,RARG,ABCA1,JARID2,DRD1,ABCG1,TBC1D10B |
| 8.826e-04 | -7.03 | FERM_domain | interpro domains | IPR000299 | 48 | 16 | 18293 | 2672 |
EPB41L5,FRMPD3,FARP1,NF2,FRMD4A,FRMD6,EZR,FRMD4B,PLEKHH2,JAK1,EPB41L4B,TLN2,EPB41L4A,MYLIP,JAK3,FARP2 |
| 8.837e-04 | -7.03 | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 178 | 42 | 17758 | 2588 |
GCLM,CDK17,IL15RA,GPR107,FOXM1,LFNG,FAM129B,IRX4,MORF4L2,MICALL2,SPSB1,SYDE2,ARHGEF10L,TOP2A,SPP1,PSMD1,ATP13A3,PIM1,NCAM1,HSPA2,RPGR,CKAP4,ATG4D,LAMP3,CXXC5,CD55,CTNNAL1,UBE2A,BTBD19,RUNX3,DUSP4,CASP4,OPTN,GLA,ATP6V1C1,TMEM120A,JAK3,SERPINB1,COL16A1,CSRP2,FAM134B,EHD1 |
| 8.837e-04 | -7.03 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | 178 | 42 | 17758 | 2588 |
MAN2B2,KLF2,TRAPPC10,ATP8A1,UBASH3B,ITGA6,EPHA4,ASAH1,SNN,HERC6,DTX3L,MARCH8,SESN3,TRANK1,IQCE,OCRL,SGK1,MARCH2,PIM1,DUSP1,SOAT1,COQ10B,RAPGEF2,RGAG1,CASP4,ZDHHC3,CDK5R1,CD83,SOCS3,IRS2,NAAA,COQ10A,NR1D2,PELI2,WDR19,CSGALNACT1,NR4A2,NFKBIZ,EPB41L4A,TOB1,MAFF,PCSK5 |
| 8.848e-04 | -7.03 | vacuolar membrane | cellular component | GO:0005774 | 320 | 68 | 17570 | 2579 |
LAMP1,GAA,SLC2A8,MAP1LC3B,GNB2,ABCD4,ATP6V0B,NAPG,ENTPD4,PQLC2,AP1M2,RDH14,ABCA2,RPN2,ECE1,MARCH2,TSPAN1,TMEM9,TMBIM1,LAMP3,LAMP2,VPS11,EVA1A,OSTM1,AP5M1,SLC11A2,SLC17A5,RHEB,GABARAPL1,ATP13A2,ENPP1,HPSE,WDR11,WIPI1,STARD3NL,RRAGD,MAN2B2,SORT1,CD63,TMEM55B,FLOT1,SLC36A4,TMEM63A,M6PR,MARCH8,ZNRF2,VASN,COL6A1,PCYOX1,DRAM1,PLEKHF1,SLC44A2,TMEM8A,ITM2C,TPCN1,P2RX4,MMD,IFITM3,LITAF,GNA11,C18orf8,GPLD1,SCARB2,CTNS,ARRB1,CTSA,PLD1,ATP6V1C1 |
| 8.922e-04 | -7.02 | CTTTGCA,MIR-527 | MSigDB lists | CTTTGCA,MIR-527 | 227 | 51 | 17758 | 2588 |
ACVR1,PAX6,CPEB4,KLHL13,NDRG1,MIER3,EGR3,AKIRIN1,DAPK2,ZCCHC17,PTEN,CASC4,ZNRF2,CALD1,OCRL,FAM13B,ENPP5,PRC1,ANKRD12,CCDC82,RP2,ACSL4,EPB41L4B,MYLIP,SMARCA2,FZD4,TACC1,SEPT6,FOXJ2,RNF165,UBE2A,RUNX3,FNDC3A,PTGFRN,DAG1,ULK2,CRISPLD2,RHOB,SOCS3,KLF12,SYT7,GNPTAB,STK38,CORO1C,C1orf21,UBE2D2,SFMBT1,NR4A2,ARPC2,NR3C2,CBX7 |
| 8.985e-04 | -7.01 | regulation of cellular component size | biological process | GO:0032535 | 315 | 68 | 16441 | 2455 |
SSH1,ADD1,RET,WDTC1,ARFGEF1,P2RX7,PLXNA1,SPTB,TP73,CDKL5,DPYSL2,DLG1,CAPG,DNM2,CTTN,SEMA3G,NEB,SEMA3B,SSH3,CLCN3,BAG4,AKT1,DMTN,DSTN,EZR,ULK2,LIMK1,TRIOBP,TMOD2,SPTBN5,NRG1,EFNA5,PLXND1,ARF6,F2RL1,SEMA6B,EPS8,CRABP2,ICAM1,SPP1,VASP,PTEN,KCNN4,MEGF8,TNFRSF12A,IQGAP3,NTN1,WNT3A,SLC12A2,HP1BP3,RAB3B,RHOA,FMN1,ANO6,PLS1,ILK,CDK5R1,RASA1,MAP1B,TSC1,SWAP70,PLEKHH2,SEMA4D,ARPC2,SEMA3A,SHROOM2,RARG,L1CAM |
| 9.002e-04 | -7.01 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour | 76 | 22 | 17775 | 2585 |
ERMP1,AKT1,ATP9A,CASP9,TP53,NUCB2,IDH1,FLT3,BCAR1,GNA11,EGFR,GNAS,RB1,INSR,CTNNB1,CDH1,PTEN,PFKL,SLC2A6,ABCA2,PIK3CA,LZTS1 |
| 9.027e-04 | -7.01 | regulation of establishment of protein localization | biological process | GO:0070201 | 785 | 149 | 16441 | 2455 |
EXPH5,TXN,LGR4,CACNA2D2,GATA3,IL18,ITPR2,SYTL4,HDAC6,BARD1,SLC8B1,ERP29,CABP1,KCNS3,DLG1,MYRIP,RASGRP1,VPS11,ACVR1C,BNIP3L,NBPF3,EZR,PRKAR2B,SLC25A5,LCP1,SLC25A4,DNM1L,RAB11FIP1,NOD2,ARF6,F2RL1,DDX58,BMF,NFKBIE,HLA-E,RAB23,FBLN1,IL18R1,ANO1,RAC2,ITGA3,PFKL,KCNN4,PRKCI,SORL1,MDFIC,CACNA1D,WNT3A,MAPK7,MDFI,EPB41L5,GCC2,WHSC1,PLS1,KIF20B,EGFR,CDK5R1,GNAS,TMEM30A,ITPR1,NFKBIA,OSCP1,YOD1,TMEM173,SORBS1,THRA,IQGAP1,TP53,ERBB2,P2RX7,CD274,BCL2L1,MICALL2,PRKACA,APC2,BCAP31,ARHGEF16,PER2,NOV,CDH1,SP100,DACT1,SMO,DAB2IP,TWIST1,MYT1,F2R,TMBIM1,CHP1,SIRT1,BAG4,ERLEC1,AKT1,PFKFB2,DMTN,PTGER4,PRKCQ,ITPR3,CD40,SNX12,FZD7,IRS2,PTGS2,PPP2R5A,WWTR1,RAB29,NRG1,EFNA5,PRKAR1A,TCAF1,PINK1,TRAF2,PSMD10,HMGN3,TGFBR1,NEO1,WWP2,KIF5B,CARD8,OXCT1,CDK16,LLGL2,BMP7,FAM20B,UBE2J1,TMBIM6,MAPK11,SYK,HES1,RHOA,SYBU,PIK3R1,RGCC,VAMP3,LITAF,PIM3,GPLD1,NUCB1,LDLRAP1,BANK1,SYT7,E2F1,ARRB1,PKD2,SPCS3,GPER1,FZD5,NDFIP1,PKIA |
| 9.047e-04 | -7.01 | PTK2 (protein tyrosine kinase 2) | protein interactions | 5747 | 135 | 36 | 16036 | 2547 |
BIN1,SORBS1,IQGAP1,RET,TP53,ERBB2,EPS8L2,SH3KBP1,NEO1,IGF1R,PTEN,DNM2,CTTN,ERBB3,PPP1CA,SYK,HES1,PIK3R1,PTPRH,EZR,TNS1,YES1,CBL,BCAR1,DAG1,EGFR,SOCS3,TSC1,PLCG1,FYN,INSR,OTUD6B,STAT1,PPP1CB,ITGAV,DEF6 |
| 9.091e-04 | -7.00 | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | 189 | 44 | 17758 | 2588 |
CD99,GALK1,NQO1,VANGL1,GNPDA1,HABP4,ERBB2,NRG2,TDRKH,ISYNA1,DHRS3,KCNC4,SSX2IP,TOP2A,CALR,CAPN2,TGFBR3,LMAN2L,TMEM62,FRYL,MDFIC,PDIA6,GFI1,MAST4,SCYL3,STAT4,PCBP3,COX11,RAD17,ITPR3,SESN1,DHX32,ENDOD1,DNAJC10,RGS9,ETS2,STK38,AMMECR1,IARS2,FAM117A,PIK3C2B,RPL22,HSPB1,DOCK9 |
| 9.091e-04 | -7.00 | GSE3982_EOSINOPHIL_VS_DC_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_UP | 189 | 44 | 17758 | 2588 |
RMND5A,ACACB,GOLIM4,SSH1,SEC61G,CNOT8,MCTP2,BIK,GRK6,KBTBD11,MAP1LC3B,DNAH3,PRR7,TEAD3,CHST2,ZNF75D,PTEN,FLRT3,KLF3,PAPSS1,ESPN,CTDSP2,DLGAP1,CENPA,TACC1,SYNE2,PYGL,KIF13A,PKMYT1,ESYT1,PCTP,STK17B,RHOB,GABARAPL1,RGS9,JAK1,WIPI1,FAM117A,AURKA,YOD1,EIF4EBP2,RGS14,JARID2,IRF1 |
| 9.091e-04 | -7.00 | GSE12366_GC_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_GC_VS_MEMORY_BCELL_DN | 189 | 44 | 17758 | 2588 |
LAMP1,KLF2,PARP12,TSC22D3,HLA-F,DGKA,ASAH1,IL27RA,TGOLN2,EGR3,NOTCH2,CAMK1D,SNN,PIGL,LTBP3,ZNF275,TMEM63A,CD46,SNX18,FOSB,TMBIM6,OAS3,CRTAP,SMAGP,DUSP1,POU6F1,CD55,FNDC3A,SESN1,RHOB,DGKE,ARHGAP24,NAAA,SERTAD2,CTNS,ANKRD6,RIN3,STAT1,PGM2L1,CTNND1,SERPINB6,SPCS3,ZMIZ1,NDFIP1 |
| 9.091e-04 | -7.00 | REACTOME_PHOSPHOLIPID_METABOLISM | MSigDB lists | REACTOME_PHOSPHOLIPID_METABOLISM | 189 | 44 | 17758 | 2588 |
PLA2G4A,MTM1,CDS2,INPPL1,PNPLA2,HEXB,ETNK1,ASAH1,PHOSPHO1,PLD2,PLA2G16,LPIN3,CDIPT,CDS1,SGPL1,INPP5E,PTEN,ARSG,OCRL,SLC44A1,PIK3CA,SLC44A2,PIK3CD,PIKFYVE,GM2A,CERS2,LPGAT1,PIK3R1,ARSK,SPTLC2,SGPP1,SLC44A3,KDSR,PI4K2B,AGPAT2,DGAT2,INPP4B,GLB1,CTSA,PIK3C2B,PLD1,GLA,ARSB,CHPT1 |
| 9.091e-04 | -7.00 | GSE10325_CD4_TCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_MYELOID_DN | 189 | 44 | 17758 | 2588 |
NFKBIE,REPS2,CDKN1C,RUSC2,HEXB,IL13RA1,NOTCH2,DSE,SIRPA,ICAM1,IL22RA1,APLP2,TNS3,METTL7A,PLCG2,OPN3,BCL6,MTMR11,SNX10,DGKG,SYK,GM2A,CCDC88A,CYP1B1,GCNT1,ALDH2,PLAUR,SAT1,PLEKHO1,EAF2,RNPEP,LHFPL2,ADRBK2,ATP10D,RBM47,PRCP,CORO1C,SLC2A6,FAM114A1,RAB31,ZDHHC7,DYSF,LTA4H,SLC31A2 |
| 9.091e-04 | -7.00 | GSE7852_LN_VS_THYMUS_TREG_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_UP | 189 | 44 | 17758 | 2588 |
HLA-E,UBASH3B,ITGA6,SNX9,TRIM68,RSAD1,BMP2K,TMEM63A,RPS6KA2,RUNDC3B,ARNT2,IFIT1,MAP3K7,OSBPL7,CPE,TMBIM1,REC8,POU6F1,OXR1,PTGER4,TTC7A,KIF13A,TANC1,KCTD2,RNPEP,CASP4,GNA11,HLA-B,PTPRJ,BANK1,NR1D2,TWSG1,PHLPP2,LRIG1,NLRC5,ABCB1,FGD6,ARRB1,AKNA,RBM43,ARSB,NR3C2,CBX7,XDH |
| 9.091e-04 | -7.00 | GSE17721_4H_VS_24H_POLYIC_BMDM_UP | MSigDB lists | GSE17721_4H_VS_24H_POLYIC_BMDM_UP | 189 | 44 | 17758 | 2588 |
DEPDC1,DNAJC3,ABCG2,GATA3,RACGAP1,GPSM2,DENND2D,ZFX,KCNN4,MITF,SLC30A6,PRKCI,SRP54,CD70,TNFRSF18,PIM1,TFG,MINPP1,PDIA6,TRAM1,S100A13,EEF1D,DVL2,CRTAP,PCCB,PSRC1,TIMP2,CDA,CALCRL,NUSAP1,CDK1,SERTAD2,SLC25A4,PLOD2,TIMM8A,NAB2,SECTM1,NFKBIZ,STK39,SERPINB6,TRAF5,HIPK3,GAB1,KLF7 |
| 9.091e-04 | -7.00 | GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP | 189 | 44 | 17758 | 2588 |
MYL9,LASP1,CPT2,RGS20,NENF,TEX2,FAM198B,NTAN1,ARHGEF40,CENPN,SIRPA,UHRF1BP1L,APLP2,ITGA3,CTSC,TNFRSF12A,TACSTD2,MYO5A,EPHX1,CKS2,LOC81691,TCEB2,CDA,ACO1,PRKAR2B,ERP44,KIF11,IDH1,ZDHHC3,STX3,VCP,CD83,FUCA1,SWAP70,PRDX3,RCBTB2,ANKRD6,WIPI1,CSF1,PLA2G15,PDXK,HSPB1,ACOT7,CYBRD1 |
| 9.091e-04 | -7.00 | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN | 189 | 44 | 17758 | 2588 |
DYRK3,IL15RA,IL15,NLRX1,HLA-E,UBASH3B,ZCCHC24,DNAJB2,EPS8,SEPP1,PRRG4,TMEM63A,RCN1,RNF128,METTL7A,MAGEE1,KIF13B,PIM1,MYLIP,PAQR7,ADCK3,CORO2A,DSTN,SAT1,SERTAD3,TMEM151A,GGH,EPHA1,NPC2,YES1,B3GALNT2,SNTB1,PCTP,NDRG3,HLA-B,ENPP1,PTPRJ,LDLRAP1,RBM47,NR1D2,PDXK,TTC39C,FBXO27,SERPINB1 |
| 9.091e-04 | -7.00 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDM_UP | 189 | 44 | 17758 | 2588 |
FBLIM1,LZTFL1,LFNG,SLC2A8,SDC4,DGKA,DNAJB11,PSME1,CHAC2,CACNB4,IFT27,ITGA2B,RAD23A,ARHGEF10L,PTEN,TMBIM6,H2AFY,TRIM21,RAB20,DAB2IP,TAGLN2,CTTN,TMEM37,SHMT1,KCNIP3,CDA,CLSTN1,HTATIP2,CD40,C18orf8,NCOA3,DNM1L,C19orf66,TMEM30A,NMI,ABCB1,GLB1,STK39,RNASEL,ATP1B3,NRBP1,ISOC1,RRAGD,NGEF |
| 9.091e-04 | -7.00 | GSE10325_CD4_TCELL_VS_BCELL_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_UP | 189 | 44 | 17758 | 2588 |
ACVR1,ITGA6,ARL4C,GATA3,CYB561,TGFBR3,TIMP1,MGAT4A,FAM102A,WWP1,PIM1,PDE4D,RCAN3,MYBL1,TIAM1,TTLL1,RASGRP1,CAMK2G,CPD,P2RX4,TMEM43,LGALS8,STAT4,CORO2A,S100A4,SLC39A8,PIK3R1,PRKCQ,OPTN,TXK,PLCG1,FYN,ATP1A1,LDLRAP1,SEMA4D,NGFRAP1,LRIG1,ARRB1,FHL1,APBA2,TBC1D4,TOB1,RPS6KA3,DOCK9 |
| 9.091e-04 | -7.00 | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN | 189 | 44 | 17758 | 2588 |
LTBP1,GCLM,SLC25A24,PLSCR4,DEPDC1,ZCCHC24,BACE1,NDC80,ERI2,COL4A5,PLXNA1,CENPN,TEAD3,PDGFA,SS18,GATA2,IMPAD1,TPST1,TAGLN2,MOXD1,FAIM,BTBD3,NAGA,CRTAP,FAH,GCNT1,OLFML2A,ALDH2,COL6A2,MMD,RAPGEF2,MGAT4B,ICMT,LDB2,CRISPLD2,DPYSL3,EDNRA,DNAJC10,FAM64A,ZDHHC7,CTNND1,YOD1,ATP1B3,SLC31A2 |
| 9.126e-04 | -7.00 | BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING | 491 | 97 | 17758 | 2588 |
GAS2L1,PNISR,ST13,PAPSS2,IBTK,TAF6L,GRK6,PJA2,PRKACA,CDK14,ZFYVE16,SS18,TYMP,AP1M2,RPS6KA2,IQCE,IL6ST,TNPO2,TRPC1,MYH14,ECE1,WBP4,DLG3,F2R,CDKN2D,TIAM1,SMAGP,SIRT1,SMARCA2,CDYL,BNIP3L,CBX6,ACO1,SLC35C1,KDELR3,RAD17,ICMT,SESN1,DAG1,EDNRA,ARHGAP35,SOCS3,CDK19,WFS1,MAOA,DLAT,PRKAR1A,GALK1,LRRFIP2,FRMD4A,JRKL,ZCCHC24,ADO,GNE,EPS8,ABCG2,C6orf106,ASAH1,RAB6A,SBF1,SEPP1,MERTK,TSPAN7,SSX2IP,DNAJB9,RND1,RB1,CDK16,FCHO1,ADAM15,LIMCH1,SYK,CRTAP,KLK5,MAPKAPK3,PIK3R1,DCHS1,MYBL2,FNDC3A,DPYSL4,LEPR,RASA1,NMT2,FAT4,COL13A1,CSF1,CGREF1,CCDC69,STK39,CDK18,HMGA1,ATP6V1C1,MAP3K5,ESPL1,RARG,ACOT7,DEF6 |
| 9.222e-04 | -6.99 | antigen processing and presentation of exogenous peptide antigen via MHC class I | biological process | GO:0042590 | 79 | 23 | 16441 | 2455 |
SEC61B,PSMB4,SEC61G,HLA-E,PSME2,HLA-F,PSMD7,TAP1,PDIA3,PSMD10,PSME1,PSMA4,HLA-A,CALR,HLA-B,TAPBP,PSMD1,PSMD3,PSMC2,ITGAV,HLA-C,PSMC1,PSMA5 |
| 9.246e-04 | -6.99 | JIANG_HYPOXIA_NORMAL | MSigDB lists | JIANG_HYPOXIA_NORMAL | 300 | 64 | 17758 | 2588 |
UGP2,GNPDA1,NDRG1,TSC22D3,SOD2,NDRG2,FTH1,PJA2,MAP1LC3B,SNX9,KREMEN1,P4HB,ZFP36,ARL1,RDH14,CAPG,CNNM4,RAB20,TFG,SNX10,GM2A,CPD,SGCE,PTPRU,SAT1,BNIP3L,MDK,HLF,AGPAT2,PTER,MAOA,SYT13,CHPT1,HSP90B1,FAM189A2,ZNF395,ENO2,SDC4,BLVRB,SIRPA,SGPL1,DTX3L,SNTA1,ADD3,TIMP1,CD9,MAPK7,CITED2,DUSP1,SPATA20,PDGFC,PRODH,DCAF6,AK4,FBXO8,BTG1,RPL12,SERTAD2,PLOD2,TMEM30A,NFKBIA,SPAG7,ATP1B3,RNF146 |
| 9.259e-04 | -6.98 | UHRF2 (ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase) | protein interactions | 115426 | 53 | 18 | 16036 | 2547 |
TRIM8,TP53,BCL2L1,CCNB1,BCAR1,CDK1,CCND1,TFAP4,RB1,FYN,CCNA2,PCNA,CTNNB1,UBE2D2,BAX,E2F1,HDAC1,JAK3 |
| 9.264e-04 | -6.98 | MODULE_491 | MSigDB lists | MODULE_491 | 76 | 22 | 17758 | 2588 |
B3GALT6,LAMP2,SYPL1,PLSCR1,FAM189A2,TUBB4B,SLC25A13,TMX4,PARP4,ASAH1,TRIB2,DENND2D,FRMD4B,IRS2,BTG1,ATP1A1,KCNN4,FBXO7,IRF2,PIKFYVE,MAD2L1BP,RPGR |
| 9.265e-04 | -6.98 | CYTOSOL | MSigDB lists | CYTOSOL | 200 | 46 | 17758 | 2588 |
HSP90B1,PEX6,KLC2,SERPINB9,XIAP,NUCB2,AIFM2,AIP,VPS26A,ATG4A,ARHGEF10L,CALR,WDFY1,PFKL,RGS3,ZFP36,STEAP2,PRKCI,BAX,TACSTD2,CCDC88A,ATG4D,SEC23A,SOD1,SHMT1,PIK3R1,CDA,ACO1,PRICKLE1,EZR,RAB3IP,IDH1,LCP1,VCP,BCL10,TSC1,LDLRAP1,PRDX3,NOD2,ARFGAP3,SERPINB6,MDH1,ANXA9,RAP1GAP,AIFM3,EGLN1 |
| 9.268e-04 | -6.98 | organic acid metabolic process | biological process | GO:0006082 | 1002 | 185 | 16441 | 2455 |
ACACB,SLC35D2,UGT8,HSPG2,AGRN,AASS,CRYM,CPT2,HEXB,MCCC1,VARS2,PLA2G16,OAT,SDC1,ECI1,CHST2,CHPF,CYP1A1,P4HB,CYP2S1,IMPAD1,ALDH1A3,PAPSS1,SLC46A1,SERINC2,ACOX2,TECR,CYP1B1,CCBL2,PRKAR2B,ICMT,IDH1,MRPS36,PNKD,CYP4F3,POR,HS6ST1,ENPP1,HPSE,UEVLD,P4HA2,IARS2,DHTKD1,ADIPOR1,PPP2R5D,PDPR,HS6ST3,DLAT,PRKAA2,FAM213B,ALDH6A1,DHPS,CYP2J2,ELOVL7,PRKAA1,ASL,ABCG2,SLC1A3,B4GALT4,PDXDC1,GNS,PFKL,CTPS1,PCYOX1,AHCY,ACAD8,GAD1,MCCC2,ABCC1,CYP26B1,CHSY3,GFPT1,FADS2,PRODH,B3GNT7,ERO1A,PDK3,PKM,AMDHD1,CYB5A,GLCE,MAPKAPK2,SLC6A6,PRKAG2,FA2H,HTT,FAAH,MDH1,B4GAT1,EGLN1,PLA2G4A,PAPSS2,UGP2,XYLT1,MGST2,SLC7A2,LPIN3,EXT2,CYP39A1,CYP26A1,PER2,XYLT2,FABP6,SRR,GOT1,APIP,ACSL4,ETHE1,MINPP1,EGLN3,SULT2B1,SULF2,GPX4,CTH,PFKFB2,PANK1,ACO1,GLO1,PXYLP1,PDHX,PTGS2,ALDH5A1,ABHD12,ACAD10,PEX2,SLC27A1,CYP2U1,HS3ST3B1,B4GALT3,LTA4H,SLC27A3,ST3GAL1,NDST3,CMAS,GCLM,ENO2,GCAT,SCD5,HAL,GNE,SDC4,CRABP2,DSE,SPR,SGPL1,SLC27A6,GPC3,GALNS,ECI2,ATP8B1,HMGCL,ABCD1,ALDH7A1,SYK,NCOA2,CRTAP,MYO5A,FAH,B3GALT6,PCCB,PGM1,B3GNT2,SHMT1,PLSCR1,GCLC,ELOVL3,OGDHL,PPARA,GGH,RNPEP,PRDX4,DDAH1,MARC1,CTNS,ACADSB,SLC35B3,PLA2G15,NR4A3,CSGALNACT1,GLB1,ACADM,ARSB,PTGES,OCLN,ACOT7 |
| 9.269e-04 | -6.98 | C2 | pfam domains | PF00168 | 122 | 32 | 16629 | 2504 |
PLA2G4A,DOC2A,RASA2,MCTP2,BAIAP3,SYTL4,SYTL2,CPNE2,RGS3,RIMS3,PLCG2,DAB2IP,WWP1,PLCB2,SYTL3,RIMS2,MCTP1,CAPN6,ITCH,ESYT1,ABR,RASA1,PLCH1,PLCG1,SYT7,RAB11FIP2,RAB11FIP1,DYSF,PIK3C2B,SYT13,TC2N,ESYT2 |
| 9.311e-04 | -6.98 | protein serine/threonine phosphatase complex | cellular component | GO:0008287 | 48 | 16 | 17570 | 2579 |
PPP4R4,PPP1R2,PPP1R12A,STRN4,PPP2R3A,PPP2R5A,PPP1R10,NKD1,PPP4R1,ITPR1,PPP2R4,PPP1CB,PPP1CA,PPP2R2D,PPP2R5D,CNEP1R1 |
| 9.311e-04 | -6.98 | phosphatase complex | cellular component | GO:1903293 | 48 | 16 | 17570 | 2579 |
PPP4R4,PPP1R2,PPP1R12A,STRN4,PPP2R3A,PPP2R5A,PPP1R10,NKD1,PPP4R1,ITPR1,PPP2R4,PPP1CB,PPP1CA,PPP2R2D,PPP2R5D,CNEP1R1 |
| 9.311e-04 | -6.98 | V$AREB6_03 | MSigDB lists | V$AREB6_03 | 244 | 54 | 17758 | 2588 |
DOC2A,PPM1J,THRA,ITGA6,DGKA,RNF182,PHF1,SSX2IP,SLC9A7,CDK14,PDGFA,CTNNBIP1,EPCAM,ARTN,LLGL2,NPNT,TACC2,SLC16A6,MEGF8,PAQR5,FUT8,SLC44A1,TOX2,H2AFY,VAT1,CDH3,ERBB3,PLCB2,TSPAN33,TRAK2,ZNF462,PVRL4,SSH3,KREMEN2,CRB3,DSTN,STRADB,KIF1C,PPP1R14C,PDE11A,DDAH1,FA2H,SH2D3C,E2F1,NR4A3,NR4A2,CTNND1,OSR1,STARD13,AHR,PRR15,FOXA1,RGMA,EHD1 |
| 9.340e-04 | -6.98 | WHITFIELD_CELL_CYCLE_G1_S | MSigDB lists | WHITFIELD_CELL_CYCLE_G1_S | 131 | 33 | 17758 | 2588 |
CCNE2,DNAJC3,SLC25A27,RAB23,INTS8,SDC1,KCNC4,BARD1,KIAA1147,DNAJB9,SLC25A36,MDM1,PCNA,HSF2,SPIN4,PASK,MSH2,ADCK2,BRD7,KANK2,CTSD,RNF113A,POLD3,ANKRD10,SPIN3,INSR,ACYP1,ZNF367,ZMYND19,CDCA7L,E2F1,TRIM45,DONSON |
| 9.346e-04 | -6.98 | NUYTTEN_NIPP1_TARGETS_UP | MSigDB lists | NUYTTEN_NIPP1_TARGETS_UP | 719 | 135 | 17758 | 2588 |
TRIM5,CUL4B,TAP1,ARFGEF1,SNX9,CTGF,NPNT,WBP4,IL1RAP,ERAP2,LAMP3,SPEF2,LHFPL2,AHRR,PI4K2B,P4HA2,LIMK1,TRIM45,TDRD7,SERPINI1,RNASEL,SLC31A2,DDX58,MRPL44,CDK17,PARP12,CYP2J2,ETV5,SLC25A27,SAMD9,SLC1A3,MECOM,SPIN4,FLRT3,STT3B,NDUFA12,GAD1,CCDC88A,GCC2,SALL4,RGMB,FHL2,KBTBD8,KIAA1109,MEST,KDM3A,PCTP,GLT8D2,STEAP1,PTPRF,TSC1,AP1AR,SLC4A4,UAP1,CGREF1,P4HA3,MATN2,YOD1,PLD1,IFIH1,C17orf75,IFI6,APOL2,RNF146,EGLN1,MFSD3,PLA2G4A,ZSWIM5,REPS2,ARMCX3,IL15,C5orf30,RASGRP3,TRANK1,SP100,RPN2,TMEM64,FAR1,MX1,RIPK2,OSTM1,SAT1,TANC1,C3orf33,CASP4,NIN,PTGS2,C19orf66,ACYP1,STAT1,ADAMTS14,GCLM,PARP14,MACC1,POC1B,BACE1,HABP4,HERC5,PBX3,BEX2,IL22RA1,ZDHHC21,CTSC,LYPD6,CALD1,ALG13,DRAM1,GTF2F2,SGK1,ITM2C,TMX1,DUSP1,PARP9,PDGFC,PHF20L1,ARAP2,PLSCR1,DEPDC4,NR4A1,OGDHL,FBXO9,SKA1,BCL10,ENDOD1,PLOD2,DHRS2,FAM3C,NMI,TMC5,NR4A3,NETO2,ERAP1,CSTF2,PGM2L1,GEM |
| 9.429e-04 | -6.97 | sulfur compound metabolic process | biological process | GO:0006790 | 366 | 77 | 16441 | 2455 |
SLC35D2,ACACB,TXN,AGRN,PAPSS2,HSPG2,AASS,XYLT1,HEXB,MCCC1,MGST2,SDC1,EXT2,CHST2,CHPF,IMPAD1,XYLT2,PAPSS1,GOT1,ACSL4,APIP,TECR,ETHE1,SULT2B1,FAR1,SULF2,CTH,SOD1,GLO1,PXYLP1,ICMT,IDH1,PDHX,HS6ST1,ENPP1,ALDH5A1,HPSE,HS3ST3B1,B4GALT3,ST3GAL1,NDST3,HS6ST3,DLAT,GCLM,SDC4,ELOVL7,B4GALT4,DSE,GSTP1,GNS,ARSG,GPC3,GALNS,PCYOX1,TPST1,AHCY,HMGCL,FAR2,MCCC2,B3GALT6,CHSY3,OPLAH,B3GNT7,PCCB,B3GNT2,GCLC,ELOVL3,GLCE,CTNS,SLC35B3,DGAT2,CSGALNACT1,GLB1,B4GAT1,ARSB,ACOT7,OCLN |
| 9.447e-04 | -6.96 | reproductive structure development | biological process | GO:0048608 | 400 | 83 | 16441 | 2455 |
GRHL2,LGR4,EPAS1,ST14,LFNG,GATA3,PLAC1,BCL2L1,SDC1,PDGFB,CCND1,CTNNB1,LRRC6,DLG1,PLK4,TIPARP,SIRT1,SOD1,AKT1,FZD4,TFAP2C,CCNF,IDH1,SOCS3,PTGS2,HS6ST1,HOXA9,AXL,E2F8,GAB1,ARNT,COL9A3,NKX3-1,CDKN1C,SERPINE2,CTSB,CENPI,BIK,SOX9,TGFBR1,MERTK,SIX4,ICAM1,SGPL1,E2F7,SPP1,DAZAP1,IGF1R,ITGB8,PTEN,CYR61,GATA2,TOX2,CST3,MSH2,BAX,TTPA,TMED2,MDFI,REC8,HES1,ASPM,FNDC3A,EGFR,PRDX4,PITX2,NCOA3,INSR,FGFR2,PRDX3,SPINT2,CTSV,SERPINB5,ARRB1,PKD2,HOXB13,SOX8,OSR1,FZD5,RARG,AHR,FOXA1,EGLN1 |
| 9.491e-04 | -6.96 | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | MSigDB lists | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | 152 | 37 | 17758 | 2588 |
DDX58,ARHGEF3,ZNF395,CPT2,RPS6KA1,GALNT12,TSC22D3,PPFIBP2,AIFM2,TSPAN7,PER2,SP100,RIMS3,BDH1,CST3,PLEKHF1,ITM2C,SGCB,HP1BP3,MBP,CITED4,CRIP2,ARFRP1,GRTP1,TMTC2,RNF19B,MAPK8IP1,NCOA3,TMEM54,SPINT2,SYT13,TTC9,LTBP2,RPL22,GLCCI1,TOB1,CBX7 |
| 9.510e-04 | -6.96 | HALLMARK_APICAL_SURFACE | MSigDB lists | HALLMARK_APICAL_SURFACE | 44 | 15 | 17758 | 2588 |
SLC2A4,RTN4RL1,SRPX,LYPD3,PLAUR,AIM1,ATP8B1,GATA3,EFNA5,TMEM8B,EPHB4,SHROOM2,HSPB1,FLOT2,SULF2 |
| 9.512e-04 | -6.96 | GEORGES_CELL_CYCLE_MIR192_TARGETS | MSigDB lists | GEORGES_CELL_CYCLE_MIR192_TARGETS | 62 | 19 | 17758 | 2588 |
TDP1,PAPD7,KIF23,RACGAP1,KIF20B,NFIB,PLS3,CDK14,NIN,RB1,SERTAD2,KIF14,PAPD5,SH3BP4,USP1,PIM1,PPP1CA,RAP1GAP,RAD21 |
| 9.512e-04 | -6.96 | PID_IL4_2PATHWAY | MSigDB lists | PID_IL4_2PATHWAY | 62 | 19 | 17758 | 2588 |
AKT1,PARP14,INPP5D,PIK3R1,IL13RA1,GTF3A,BCL2L1,CBL,ETS1,SOCS3,IRS2,JAK1,STAT6,BCL6,PIK3CA,HMGA1,MYBL1,JAK3,SOCS5 |
| 9.512e-04 | -6.96 | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | MSigDB lists | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | 62 | 19 | 17758 | 2588 |
CCNE2,PSMB4,PSME2,PSMD7,CUL1,PSMD10,PSME1,PKMYT1,PSMA4,WEE1,RB1,CCNA2,PSMD1,PSMD3,PSMC2,CKS1B,CDKN1B,PSMC1,PSMA5 |
| 9.514e-04 | -6.96 | APOPTOSIS_GO | MSigDB lists | APOPTOSIS_GO | 427 | 86 | 17758 | 2588 |
CASP3,ACVR1,GRIK2,XIAP,TP53,CUL1,BCL2L1,AIFM2,BARD1,TNFSF9,IER3,TP73,CDKN2C,DAPK2,SIVA1,BCL6,CDKN1B,TNFRSF18,F2R,CDKN2D,MX1,BAG4,SOD1,AKT1,ACVR1C,CASP9,BNIP3L,HTATIP2,GLO1,STK17B,CDK1,CASP4,VCP,SOCS3,DNM1L,MADD,STAT1,HDAC1,HSPB1,AIFM3,CBX4,BMF,HSP90B1,DAP,CTSB,BIK,SERPINB9,NCKAP1,NOTCH2,GSTP1,ADAMTSL4,SGPL1,CALR,TOP2A,CARD8,ADORA1,IGF1R,PTEN,BAX,DAPK1,CD70,PIM1,ERCC2,TMX1,GCLC,RUNX3,CYFIP2,BCAR1,RHOB,CDK5R1,RASA1,STK17A,FAS,BCL10,BTG1,CASP7,SEMA4D,HTT,SCG2,NFKBIA,E2F1,MAP3K5,IFI6,HIPK3,ESPL1,AHR |
| 9.515e-04 | -6.96 | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | 184 | 43 | 17758 | 2588 |
DDX58,GSDMD,CAMKK1,HLA-E,ZCCHC24,DNAJB2,HDAC11,SLC20A1,FAM101B,KBTBD11,PHF1,SUSD2,OTUD1,CDH1,TLN2,RBMS2,FARP2,P2RX4,POU6F1,DDB2,TEF,FOXJ2,RAPGEF2,CASP9,IGSF8,ARFRP1,FAM73B,BBS2,ZDHHC3,TCN2,DGKE,HS6ST1,BTG1,RPL12,NR1D2,NR4A3,ARRB1,ALG2,PER3,CBX7,CBX4,JARID2,ARHGEF4 |
| 9.564e-04 | -6.95 | NRG1 (neuregulin 1) | protein interactions | 3084 | 66 | 21 | 16036 | 2547 |
NEK4,B3GNT2,TMTC3,FAM234B,GYLTL1B,C1GALT1C1,ERBB2,DSE,B3GALNT2,SPTLC2,PGAP1,EGFR,TMEM164,HS6ST1,MGAT1,LIMK1,ATP7B,NETO2,ERBB3,POMT1,POMGNT2 |
| 9.568e-04 | -6.95 | single-organism cellular localization | biological process | GO:1902580 | 906 | 169 | 16441 | 2455 |
DOC2A,AGRN,GRIK2,NDC80,TRAPPC8,F11R,MPP5,KIF2C,SYTL4,CCNB1,PICK1,ZFYVE16,RAB15,CTNNB1,DPYSL2,DLG1,DNM2,SNX16,KIF22,PIK3CD,TFG,PACSIN1,TRAM1,CPE,S100A13,RASGRP1,KCNIP3,CENPA,SYNE3,UXT,EZR,ARFRP1,KIF13A,ICMT,MCFD2,OPTN,TRIM9,AREG,GNPTAB,KPNA2,TC2N,GRN,PEX6,SEC61G,ETV5,RAB6A,GPSM2,LMNA,ATG4A,GATA2,RPL39,FBXO7,PRKCI,SRP54,SORL1,SYTL3,NUP85,PPP6R1,TSPAN33,TMED2,NAGPA,PMPCB,GCC2,SCRIB,ZDHHC3,EGFR,STX3,SCARB2,TIMM8A,HTT,ZDHHC20,CDCA5,NFKBIA,RAB31,ZDHHC7,ATP1B3,NDE1,JAK3,TOB1,DRD1,MTM1,DLGAP5,TP53,P2RX7,PKP2,EMP2,SYTL2,ZFYVE9,CDH1,KIF14,ZDHHC12,REEP1,BCL6,ZDHHC23,TNPO2,RPN2,RAB27B,DLG3,LMAN1,FLOT2,F2R,ATG4D,SEC23A,SEC61B,BAG4,PSRC1,AKT1,SYNE2,VPS4B,NUSAP1,ATP1B1,RAB38,DAG1,PEX5,DDOST,PEX2,CHMP4B,SYT13,RPL22,COPG1,TAOK2,TRAPPC10,TSPAN15,LRP4,FLOT1,CDCA8,PDIA3,CTSZ,PLD2,SPDL1,TSPAN17,AIP,ZDHHC21,KIF5B,ANK1,ADORA1,CTSC,PPP1R10,LLGL2,BAX,PLEKHF1,CPLX1,SYK,SPRY2,MYO5A,HES1,SUN2,RAB3B,CRB3,RAPGEF2,ASPM,PIK3R1,VAMP3,PRICKLE1,COL7A1,RAB3IP,BBS2,MAP1B,RGPD5,RPL12,SERPINA1,FGFR2,SYT7,NR4A3,SSNA1,CENPE,SPCS3,ESPL1,SNPH |
| 9.604e-04 | -6.95 | PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP | MSigDB lists | PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP | 81 | 23 | 17758 | 2588 |
SUN1,GCLM,BCAM,CENPA,HJURP,KIF20A,MPP1,CDCA8,ASB9,BCL2L1,MAN2A2,CTGF,ETS2,KIAA0141,ELMO2,IMPAD1,OSMR,KPNA2,FHL1,PLIN3,PPP2R5D,HP1BP3,XKR8 |
| 9.679e-04 | -6.94 | cytokinesis | biological process | GO:0000910 | 84 | 24 | 16441 | 2455 |
PLK1,RHOA,KIF20A,ARHGEF11,KLHL13,CKAP2,CIT,SEPT6,DIAPH2,KIF23,KIF13A,NUSAP1,RACGAP1,AURKB,BCL2L1,CNTROB,ANLN,SNX9,RHOB,RASA1,RALB,SNX18,PRC1,ESPL1 |
| 9.722e-04 | -6.94 | GSE20715_0H_VS_6H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_6H_OZONE_LUNG_DN | 195 | 45 | 17758 | 2588 |
NUDT6,HSPG2,IBTK,FRMD6,INPP5D,ITGA6,RHBDL3,OSGIN2,GALM,EFNB1,PDXDC1,ELF3,SPP1,KCNK5,A4GALT,RAB20,LIMCH1,CRY2,NPTXR,OSGIN1,WBP5,DPYSL5,GCLC,DRAP1,CDYL,FURIN,ITPR3,DPYSL4,POR,LEPR,STX3,SOCS3,RGS9,PI4K2B,AREG,SEC14L4,PELI2,NKD1,CLIP4,OSMR,CDK18,RCAN2,PLD1,POMT1,COL16A1 |
| 9.722e-04 | -6.94 | SHEPARD_BMYB_MORPHOLINO_DN | MSigDB lists | SHEPARD_BMYB_MORPHOLINO_DN | 195 | 45 | 17758 | 2588 |
SLC25A24,DLGAP5,FOXM1,CKAP2,DAP,BLVRB,CDCA3,PDCL,KIF23,COL4A5,NOTCH2,CCNB1,EPDR1,IRF2BPL,ACAP2,KIF14,PRC1,MSH2,IGFBP2,IQGAP3,LAMP2,PHF20L1,ASPM,SEPT6,DRAP1,MGAT4B,CDC20,PYGL,CDCA2,AURKB,ANLN,KIF11,CDK1,TCN2,PRIM1,MDK,ATP1A1,CCNB3,DCK,CDCA7L,HMGA1,NDE1,MELK,SRSF9,GOLGB1 |
| 9.722e-04 | -6.94 | GSE20715_0H_VS_48H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_UP | 195 | 45 | 17758 | 2588 |
SORT1,ZNF395,FAM198B,TSPAN17,EPS8L2,WWP2,CDKN2C,DAPK2,NUP210,RPS6KA2,FAM20C,DACT1,ELF5,SLC44A2,SORL1,POF1B,LIMCH1,TACSTD2,RFX5,PXMP4,MYLIP,PTPRE,ARAP2,HPS3,IFITM3,CR2,FBXO8,ARHGDIB,SRSF5,SESN1,PLEKHB1,CMTM7,SLC6A6,ACYP1,H1F0,NMI,FGF18,RAB31,MAOA,FHL1,AKNA,CD81,GLCCI1,SERPINB1,GAB1 |
| 9.827e-04 | -6.93 | PLAUR (plasminogen activator, urokinase receptor) | protein interactions | 5329 | 107 | 30 | 16036 | 2547 |
CHSY3,NEK4,GCLM,CERCAM,CDYL,MGAT4B,GYLTL1B,LOXL2,NOTCH2,PKN1,ARSK,SRPX2,DNAJB9,MAN2A2,PI4K2B,FYN,JAK1,OXCT1,IL6ST,GALNS,PCYOX1,EGFL7,CTSA,XRCC3,CTTN,ARSB,POMGNT2,MGAT5,MELK,PCSK5 |
| 9.830e-04 | -6.92 | LINDSTEDT_DENDRITIC_CELL_MATURATION_B | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_B | 53 | 17 | 17758 | 2588 |
TNIP1,IL15RA,PSME2,SDC4,TAP1,DUSP4,CD83,OPTN,PDGFA,BTG1,CASP7,NFKBIA,NR4A3,KLF5,NFKB2,MAFF,LAMP3 |
| 9.853e-04 | -6.92 | BIOCARTA_MAPK_PATHWAY | MSigDB lists | BIOCARTA_MAPK_PATHWAY | 86 | 24 | 17758 | 2588 |
MAP3K3,MAPKAPK3,RPS6KA1,RAPGEF2,TRAF2,TGFBR1,MAPK4,ELK1,FOS,MAP3K6,MAPKAPK2,RPS6KA2,NFKBIA,PAK2,STAT1,MAP3K9,MAP3K11,MAPK13,MAPK11,MAP3K7,MAP3K5,MAPK7,RPS6KA3,MAPK12 |
| 9.897e-04 | -6.92 | negative regulation of nucleocytoplasmic transport | biological process | GO:0046823 | 70 | 21 | 16441 | 2455 |
TXN,NFKBIE,THRA,LITAF,RAB23,PSMD10,BARD1,APC2,NOV,SP100,BMP7,CABP1,WWTR1,NFKBIA,DAB2IP,PKD2,MDFIC,MAPK7,PKIA,MDFI,CHP1 |
| 9.927e-04 | -6.92 | RDX (radixin) | protein interactions | 5962 | 75 | 23 | 16036 | 2547 |
VPS11,TRAPPC10,CALM1,EZR,PLS1,ISYNA1,NOTCH2,SLC9A3R2,BCAP31,LCP1,VCP,PLS3,RCN1,CALR,TSC1,CPNE2,P4HB,PHLPP2,AKR1B1,TAGLN2,CTTN,ATP6V1C1,L1CAM |
| 9.948e-04 | -6.91 | negative regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070303 | 39 | 14 | 16441 | 2455 |
TP73,PINK1,AKT1,FOXM1,DACT1,ITCH,PBK,DLG1,DUSP10,EZR,F2RL1,GSTP1,HIPK3,MECOM |
| 9.948e-04 | -6.91 | anatomical structure maturation | biological process | GO:0071695 | 39 | 14 | 16441 | 2455 |
BMP2,RHOA,FAT4,ACVRL1,SEMA4D,ANO6,RET,DCHS1,GRIN1,GATA3,PHOSPHO1,ERCC2,DAG1,CDK5R1 |
| 9.948e-04 | -6.91 | negative regulation of stress-activated MAPK cascade | biological process | GO:0032873 | 39 | 14 | 16441 | 2455 |
TP73,PINK1,AKT1,FOXM1,DACT1,ITCH,PBK,DLG1,DUSP10,EZR,F2RL1,GSTP1,HIPK3,MECOM |
| 1.002e-03 | -6.91 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | 91 | 25 | 17758 | 2588 |
GCA,CTHRC1,BVES,LMCD1,KCTD12,PDGFRL,IL13RA1,EGR3,EPHA1,ATP1B1,FOS,HDAC9,ENPP1,NPNT,METTL7A,FLRT3,CDH3,RCAN2,IFIT1,TINAGL1,AKIP1,NTN1,ABCA1,L1CAM,SEMA3B |
| 1.002e-03 | -6.91 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | MSigDB lists | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | 91 | 25 | 17758 | 2588 |
AKT1,NR4A1,CALM1,CASP9,PIK3R1,CALM3,PRKAR2B,ITPR2,ITPR3,PHLPP1,PRKACA,PDGFB,BCAR1,CDK1,RASA1,CALM2,PDGFA,PLCG1,ADRBK1,PTEN,STAT6,STAT1,PIK3CA,CDKN1B,PRKAR1A |
| 1.002e-03 | -6.91 | CEACAM21 (carcinoembryonic antigen-related cell adhesion molecule 21) | protein interactions | 90273 | 45 | 16 | 16036 | 2547 |
PODXL2,HLA-F,EPHA4,TNFSF9,EFNB1,DAG1,XPR1,PTPRF,FAT4,PVRL2,PTK7,FUT8,RYK,EXOC8,HSPA13,MOXD1 |
| 1.005e-03 | -6.90 | pallium development | biological process | GO:0021543 | 149 | 37 | 16441 | 2455 |
ANXA3,EMX1,CASP3,NF2,ADGRG1,CNTNAP2,TP73,FOXP2,CTNNB1,PTEN,TACC2,KIF14,LHX6,SMO,BAX,DAB2IP,DIXDC1,ZBTB18,WNT3A,BTBD3,RHOA,TACC1,ASPM,GRIN1,TFAP2C,BBS2,CDK5R1,EGFR,MDK,TSC1,FAT4,PHLPP2,NR4A3,NDE1,WDR62,SEMA3A,DRD1 |
| 1.005e-03 | -6.90 | establishment of protein localization | biological process | GO:0045184 | 1303 | 234 | 16441 | 2455 |
LAMP1,EXPH5,UNC93B1,FAF2,GRIK2,ARFGEF1,TAP1,GATA3,UBE2Q1,TRAPPC8,F11R,MPP5,SYTL4,HDAC6,SNX9,NUP62CL,ERP29,PICK1,ZFYVE16,NAPG,RAB15,AP1M2,NUP210,RABEP2,NPNT,LMAN2L,DNM2,SNX16,RAB20,RP2,CTTN,PACSIN1,TRAM1,MYRIP,S100A13,PLK1,LAMP2,VPS11,SYNE3,KDELR3,EZR,ARFRP1,KIF13A,ICMT,MCFD2,RNF19B,RAB2B,ARF4,VCP,OPTN,TRAM2,TBC1D17,UEVLD,GNPTAB,RAB11FIP1,NOD2,KPNA2,ARF6,APBA2,F2RL1,NXT2,PCSK5,GGA1,PEX6,SEC61G,RAB23,ATP6V1E2,RAB6A,APBA1,FAM21C,PGAP1,LMNA,ATG4A,CALR,DOPEY2,SNX18,RINL,FRAS1,RPL39,KIF13B,NECAB3,FBXO7,EXOC8,PRKCI,SRP54,SORL1,CADPS2,SYTL3,NUP85,TSPAN33,TMED2,RIMS2,SNX7,KDELR1,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,KIF20A,BTN3A2,STRADB,CALCRL,GOLT1A,ZDHHC3,RHOB,EGFR,STX3,GNAS,AP1AR,SCARB2,TIMM8A,HTT,ZDHHC20,NFKBIA,RAB31,ZDHHC7,CTSA,LTBP2,HOOK1,JAK3,TOB1,NUP58,SNX30,DRD1,EHD1,MTM1,C5orf30,TP53,PKP2,MVB12B,BCAP31,ZFYVE9,APPBP2,SYTL2,ATP6V0B,SVBP,CDH1,ZDHHC12,KIF14,REEP1,BCL6,ZDHHC23,TNPO2,STEAP3,RPN2,IFIT1,LMAN1,RAB27B,ARL4D,F2R,SNX10,FLOT2,ATG4D,CHP1,MYO5B,SNX8,SEC23A,SEC61B,AKT1,COG2,DMTN,VPS4B,AP5M1,SLC11A2,ATP1B1,RAB38,SNX12,ATP10D,DAG1,PEX5,STX10,DDOST,CORO1C,PEX2,CHMP4B,RAB29,RPL22,ABCA1,COPG1,TTC8,PINK1,HSP90B1,TAOK2,CD63,TSPAN15,FLOT1,BTN3A1,PDIA3,IFT27,TSPAN17,AIP,VPS26A,ZDHHC21,PDIA4,SNX13,ANK1,ADORA1,MLPH,PPP1R10,FAM160A2,RRBP1,BAX,H2AFY,TRIM3,CPLX1,SYK,RPGR,CAMK2G,MYO5A,HES1,LCA5,RAB3B,DENND1B,PIK3R1,EIF5A2,VAMP3,PRICKLE1,RAB3IP,NEURL1B,BBS2,RGPD5,RPL12,MAMDC4,RAB11FIP2,SCG2,ARFGAP3,ARRB1,SPCS3,ATP6V1C1,CEP41,NUP37,RAB3IL1,ABCG1 |
| 1.007e-03 | -6.90 | response to organonitrogen compound | biological process | GO:0010243 | 907 | 169 | 16441 | 2455 |
CASP3,SSH1,NRG2,PSME1,ITPR2,PDGFB,SDC1,SPTB,TP73,CALM2,SESN3,PSMD1,CTNNB1,CTGF,SHC3,DPYSL2,PSMC2,KLF3,FOSB,PIK3CA,DNM2,AKR1B1,RASGRP1,SOD1,ACVR1C,EZR,PRKAR2B,POR,RHEB,ENPP1,AREG,NOD2,CAB39,EIF4EBP2,PSMC1,GAB1,RRAGD,PRKAA2,KLF2,INPPL1,RASA2,DGKQ,SOX9,PRKAA1,PSMD7,ATP6V1E2,CALM3,DUSP5,TIMP1,IGF1R,COL6A1,PRKCI,NCAM1,PSMA5,CALM1,STRADB,PSMA4,EGFR,RASA1,GNAS,TSC1,INSR,PRKAG2,NFKBIA,SH3BP4,RAB31,NR4A2,JAK3,TRPC3,COL16A1,DRD1,SPRED1,SORBS1,SLC2A4,FOXM1,PSME2,SLC2A8,WDTC1,ERBB2,P2RX7,RASGRP3,BCL2L1,PRKACA,GNB2,PDGFA,CCND1,ATP6V0B,CCNA2,CDH1,SRR,CDKN1B,DAB2IP,GOT1,PDE4D,RASGEF1A,FRS3,SIRT1,AKT1,RIPK2,DMTN,PRKCQ,ERBB2IP,DAG1,CASP4,SOCS3,IRS2,DUOX1,PTGS2,FYN,IDE,JAK1,PSMD3,STAT1,SLC27A1,NRG1,SPTBN5,LTA4H,PRKAR1A,HSP90B1,SORT1,CPEB4,CTSB,GNAL,PSMD10,SELL,GABRG2,FGF19,ICAM1,HDAC9,CAPN2,IRAK1,PTEN,BMP7,BAX,TMBIM6,ERBB3,CAMK2G,MYO5A,GCNT1,DUSP1,HCN3,P2RX4,PDGFC,RASGRF1,RHOA,SHMT1,ADAM17,PSMB4,WNT10B,RAPGEF2,NR4A1,PIK3R1,GRIN1,PPARA,GGH,YES1,FOS,BCAR1,GPLD1,BTG1,TIMP3,FGFR2,FGF18,NR4A3,GRIN2D,GPER1,ATP6V1C1,TBC1D4,CPEB2 |
| 1.009e-03 | -6.90 | Regulation of Microtubule Cytoskeleton | WikiPathways | WP2038 | 44 | 16 | 4455 | 729 |
SPRED1,MARK1,AKT1,TESK2,KIF2C,AURKB,PRKACA,CDK1,MAP1B,MAPKAPK2,PTEN,LIMK1,DPYSL2,PIK3CA,WNT3A,TIAM1 |
| 1.011e-03 | -6.90 | ENDOPLASMIC_RETICULUM_PART | MSigDB lists | ENDOPLASMIC_RETICULUM_PART | 96 | 26 | 17758 | 2588 |
PIGC,HSP90B1,AMFR,PDIA5,ERP44,EXT2,KTN1,PDIA4,CALR,RCN1,TAPBP,CASP7,DDOST,STIM1,DOLPP1,LMAN2L,SLC9A6,NECAB3,BAX,ERAP1,RPN2,STT3B,LMAN1,POMT1,ERAP2,TMX1 |
| 1.011e-03 | -6.90 | regulation of organelle organization | biological process | GO:0033043 | 1022 | 188 | 16441 | 2455 |
SSH1,ADD1,ARFGEF1,GATA3,F11R,CCNB1,HDAC6,PDGFB,SDC1,MAP1LC3B,SPTB,PHF1,PICK1,NPM2,RPS6KA2,CTNNB1,CTGF,SIVA1,DDHD2,DLG1,CAPG,DNM2,TACSTD2,CTTN,NEB,PLK1,VPS11,DSTN,BNIP3L,NBPF3,EZR,PIF1,AURKB,CCNF,ANLN,SLC25A5,LCP1,TRIM9,TBC1D17,MID1IP1,ARHGEF19,DNM1L,PLK2,LIMK1,TMOD2,ARF6,F2RL1,BMF,TBC1D1,SORBS3,RACGAP1,NCKAP1,LMNA,CORO1B,CALR,RB1,RAC2,VASP,IGF1R,GATA2,TBCD,NEK2,MSH2,SLAIN2,KNTC1,PIKFYVE,WNT3A,CCDC88A,PIP4K2C,KIF20B,EPHA1,ILK,KDM3A,NUBP1,RASA1,CDK5R1,TSC1,AP1AR,INSR,PLEKHH2,HTT,CDCA5,ARAP1,AURKA,OSCP1,ARPC2,SHROOM2,AFAP1,CTBP1,ADAMTS16,GAS2L1,MTM1,NF2,DLGAP5,PTTG1,TP53,P2RX7,BCL2L1,MICALL2,PATL2,APC2,MNS1,IER3,PDGFA,RALB,BCL6,PLK4,CDKN1B,VAT1,DIXDC1,TWIST1,ESPN,LMAN1,TBC1D10B,SIRT1,PPIF,SSH3,CAMSAP3,PSRC1,BAG4,AKT1,CAPN6,DMTN,CDC20,PTGER4,VPS4B,PRKCQ,NUSAP1,PKMYT1,CDC25C,TRIOBP,XRCC3,CHMP4B,NRG1,SPTBN5,EFNA5,MAD2L1BP,GEN1,PRKAR1A,PINK1,CKAP2,CIT,EPS8,SDC4,BIK,PSMD10,NES,ICAM1,CAPN2,ANK1,PTEN,CENPJ,BMP7,FAM20B,TUBGCP6,BAX,BRD7,H2AFY,BUB1,CNOT6L,GFI1,MYO5A,HES1,RHOA,FMN1,PLAUR,PIK3R1,RGCC,STMN3,SKA1,BORA,KIF11,MPV17L2,CNOT2,SWAP70,FGFR2,CTSV,TADA2B,E2F1,ARRB1,GPER1,CENPE,HMGA1,FZD5,TBC1D4,UBE2C,ESPL1,JARID2 |
| 1.017e-03 | -6.89 | organelle fission | biological process | GO:0048285 | 487 | 98 | 16441 | 2455 |
SUN1,SPC25,DLGAP5,LFNG,SLC2A8,ACTR8,PTTG1,NDC80,XIAP,NUF2,TDRKH,KIF2C,CCNB1,SNX9,CENPN,WEE1,CCNA2,SETDB2,KIF14,KIF22,HSPA2,CKS2,PLK1,NEK4,PSRC1,PBK,CDC20,VPS4B,CDCA2,NUSAP1,PKMYT1,AURKB,CCNF,ANLN,CDC25C,CDK1,DNM1L,TRIOBP,XRCC3,CHMP4B,RGS14,SGOL1,REEP4,PPP2R2D,ZC3HC1,PRKAR1A,PPP1R12A,KLHL13,CIT,EPS8,CDCA3,ERCC6L,CDCA8,KIF23,RACGAP1,SPDL1,CKAP5,SAC3D1,TOP2A,RB1,SNX18,PTEN,TUBGCP6,NEK2,MSH2,BAX,BUB1,KNTC1,MSH6,SMC4,CYP26B1,REC8,RHOA,ZWINT,CENPC,PAPD7,ASPM,MYBL2,KIF20B,SKA1,BORA,KIF11,FAM64A,PAPD5,CDCA5,FAM83D,AURKA,CENPE,GEM,NDE1,NUP37,NCAPG2,CCNB2,UBE2C,ESPL1,USP16,FBXW5,RAD21 |
| 1.018e-03 | -6.89 | regulation of cell morphogenesis involved in differentiation | biological process | GO:0010769 | 322 | 69 | 16441 | 2455 |
SSH1,EPHA4,RET,PLXNA1,CTNNB1,CDKL5,DPYSL2,DNM2,DAB2IP,TWIST1,TACSTD2,SEMA3G,CTTN,TIAM1,SEMA3B,SSH3,DMTN,DAG1,ULK2,BHLHB9,CORO1C,LIMK1,WWTR1,SIPA1L1,TRIOBP,STAT1,EFNA5,NRG1,PLXND1,ITPKA,LZTS1,SEMA6B,ARHGEF7,CIT,LRP4,TGFBR1,CRABP2,FAM21C,FBLN1,CALR,BMP2,SPP1,PTEN,KNDC1,VASN,KIF13B,MEGF8,TNFRSF12A,WNT3A,NTN1,TRIM62,EPB41L5,RHOA,MFI2,RAPGEF2,GRIN1,RGCC,ILK,CDK5R1,MAP1B,AP1AR,SEMA4D,EFNA1,ARPC2,SHOX2,SEMA3A,L1CAM,FOXA1,NGEF |
| 1.019e-03 | -6.89 | GSE17721_POLYIC_VS_CPG_12H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_12H_BMDM_UP | 190 | 44 | 17758 | 2588 |
LASP1,TMEM184B,CHCHD7,ST14,S100A11,TSC22D3,DAP,PTTG1,TAF6L,MGST2,CCDC92,TAF1B,PTEN,SLC44A1,TMEM51,SORL1,BRI3,RFX5,PIK3CD,TMEM37,MX1,GCA,STAT4,SNTB2,CYS1,SAT1,SPTLC2,CASP4,STX3,ARF4,ATP13A2,BCAR3,NAAA,NCOA3,C19orf66,NAT1,SPINT2,FAM110C,DCUN1D1,ZNF704,TRIOBP,TOB1,IRF1,RAD21 |
| 1.019e-03 | -6.89 | GSE3982_BCELL_VS_TH1_DN | MSigDB lists | GSE3982_BCELL_VS_TH1_DN | 190 | 44 | 17758 | 2588 |
ANXA3,MRC2,SPC25,IL15RA,DLGAP5,FOXM1,ATP9A,ZCCHC24,PTTG1,TAP1,FLOT1,KIF2C,BARD1,SPSB1,PDGFA,SPP1,BTG3,PRC1,ABCA2,KCNS3,BUB1,CTTN,SPRY2,CKS2,PLK1,PPIF,MPP1,CORO2A,AK4,WHSC1,STEAP1,OPTN,SFXN1,RBM47,TWSG1,NEIL3,AMMECR1,SECTM1,CLIP4,KPNA2,REEP4,STARD13,ACOT7,RPS6KA3 |
| 1.019e-03 | -6.89 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN | 190 | 44 | 17758 | 2588 |
SORBS1,ENO2,NF2,SERPINE2,IL15,AASS,SUDS3,FTH1,OAT,DHRS3,M6PR,CTNNBIP1,ZFX,CD9,HLA-C,APIP,RAG1,NFKB2,ABCC1,SOCS5,ZWINT,STAT4,PTGER4,LITAF,EZR,IGSF8,LCP1,ARF4,EBF2,GABARAPL1,IL1R1,TSC1,FYN,ATP1A1,COQ10A,CCDC6,CORO1C,OSMR,ATP1B3,GLA,PSMC1,AHR,JARID2,EHD1 |
| 1.019e-03 | -6.89 | GSE27786_LIN_NEG_VS_NKTCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_NKTCELL_UP | 190 | 44 | 17758 | 2588 |
CCNE2,UNC93B1,CPT2,SWI5,SORBS3,SNX9,LMNA,KIAA0895,P4HB,METTL7A,SMO,PRC1,SGK3,OPN3,KNTC1,ERBB3,KANK3,TMEM9,MGAT5,KCTD3,HCN3,HMMR,ATL1,SGCE,CITED4,CRIP2,CKAP2L,AK4,TMEM151A,WHSC1,CDCA2,AURKB,RNPEP,DCAF10,DHRS13,TWSG1,CSTF2,AURKA,DMWD,GLA,SOX8,POMT1,SLC25A38,NCAPG2 |
| 1.020e-03 | -6.89 | YTATTTTNR_V$MEF2_02 | MSigDB lists | YTATTTTNR_V$MEF2_02 | 660 | 125 | 17758 | 2588 |
SLC2A4,SPC25,TRIP10,VANGL1,GRIK2,CAST,DNAJC3,RHBDL3,EPHX4,SMARCAL1,MORC4,KTN1,SPTB,ZNF385B,CCND1,PDGFA,HSF2,CTGF,CDKL5,ARHGEF37,NPNT,DACT1,KLF3,FOSB,MITF,BCL6,DUSP10,TWIST1,RAB20,PHKA2,SMARCA2,TIMP2,MARK1,CITED4,PANK1,KIF13A,PRKAR2B,ZFAND5,SP4,NFIX,DZIP1L,ENPP1,RTN4RL1,PEX5,KCNMB4,KLF12,WIPI1,SIPA1L1,ADAMTS14,KLF5,CTNND1,C1orf43,LIFR,NR3C2,FAM134B,PRKAA2,IER5L,CTHRC1,RECQL,INPPL1,FRMD4A,SCOC,GCAT,DNAJB2,PBX3,ETS1,PGAP1,NFAT5,ANO1,PPP2R3A,SIRPA,NRP2,LMNA,GBX2,SCML1,HDAC9,FOXP2,IRAK1,PPP1R10,ANKS1B,FLRT3,BMP7,ZIC5,TFAP2A,NEK2,NCAM1,SGCB,RIMS2,CRTAP,C9orf9,WBP5,TRAK2,SNX7,RASGRF1,HES1,PHF20L1,ARAP2,CASK,NR4A1,VAMP3,PPARA,STRADB,VEZT,UNC45B,GOLT1A,FOS,NDRG3,NFIB,MUM1L1,GPLD1,GNAS,TSC1,SEMA4D,ITGA7,NEIL3,AMMECR1,NAB2,C1orf21,RAP2C,GRIN2D,CTSA,MAL2,HIPK3,RNF146,DMPK |
| 1.020e-03 | -6.89 | CD82 (CD82 molecule) | protein interactions | 3732 | 41 | 15 | 16036 | 2547 |
CD46,ITGA3,CTNNB1,VANGL1,CD63,AMFR,ITGA6,CD9,ERBB2,IGSF8,ERBB3,PTGFRN,CD81,LGALS3BP,EGFR |
| 1.020e-03 | -6.89 | ARHGAP32 (Rho GTPase activating protein 32) | protein interactions | 9743 | 41 | 15 | 16036 | 2547 |
PLCG1,FYN,CAMK2N2,RHOA,CTNNB1,CDH1,NF2,AKT1,SHC3,PIK3R1,ARRB1,AES,BCAR1,GAB1,MDFI |
| 1.024e-03 | -6.88 | PROGRAMMED_CELL_DEATH | MSigDB lists | PROGRAMMED_CELL_DEATH | 428 | 86 | 17758 | 2588 |
CASP3,ACVR1,GRIK2,XIAP,TP53,CUL1,BCL2L1,AIFM2,BARD1,TNFSF9,IER3,TP73,CDKN2C,DAPK2,SIVA1,BCL6,CDKN1B,TNFRSF18,F2R,CDKN2D,MX1,BAG4,SOD1,AKT1,ACVR1C,CASP9,BNIP3L,HTATIP2,GLO1,STK17B,CDK1,CASP4,VCP,SOCS3,DNM1L,MADD,STAT1,HDAC1,HSPB1,AIFM3,CBX4,BMF,HSP90B1,DAP,CTSB,BIK,SERPINB9,NCKAP1,NOTCH2,GSTP1,ADAMTSL4,SGPL1,CALR,TOP2A,CARD8,ADORA1,IGF1R,PTEN,BAX,DAPK1,CD70,PIM1,ERCC2,TMX1,GCLC,RUNX3,CYFIP2,BCAR1,RHOB,CDK5R1,RASA1,STK17A,FAS,BCL10,BTG1,CASP7,SEMA4D,HTT,SCG2,NFKBIA,E2F1,MAP3K5,IFI6,HIPK3,ESPL1,AHR |
| 1.028e-03 | -6.88 | ER-associated ubiquitin-dependent protein catabolic process | biological process | GO:0030433 | 61 | 19 | 16441 | 2455 |
UFD1L,SEC61B,FAF2,ERLEC1,HSP90B1,DNAJB2,JKAMP,AMFR,FBXO2,FBXO6,VCP,DNAJB9,DNAJC10,WFS1,PSMC2,UBE2J1,YOD1,STT3B,PSMC1 |
| 1.028e-03 | -6.88 | lysosomal transport | biological process | GO:0007041 | 61 | 19 | 16441 | 2455 |
NAGPA,LAMP1,GCC2,MTM1,VPS11,SORT1,KIF13A,RHOB,HMGXB4,M6PR,ZFYVE16,SCARB2,FAM160A2,GNPTAB,SNX16,SORL1,SPTBN5,ARSB,HOOK1 |
| 1.030e-03 | -6.88 | platelet activation | biological process | GO:0030168 | 234 | 53 | 16441 | 2455 |
PLA2G4A,MYL9,CD63,DGKQ,HABP4,DGKA,CALM3,ITPR2,PDGFB,MERTK,ITGA2B,FZD6,PDGFA,CALM2,RAC2,TIMP1,PLCG2,CD9,PIK3CA,WNT3A,F2R,DGKG,SYK,RASGRP1,TUBA4A,LAMP2,SOD1,RHOA,PLSCR1,AKT1,CALM1,PIK3R1,C1GALT1C1,PRKCQ,CD40,ILK,ITPR3,BCAR1,GNA11,MYL12A,RHOB,DGKE,RASGRP2,DGKH,GNAS,FYN,SERPINA1,ABHD12,AXL,ITPR1,ARRB1,HSPB1,TRPC3 |
| 1.031e-03 | -6.88 | lung cell differentiation | biological process | GO:0060479 | 27 | 11 | 16441 | 2455 |
THRB,KLF2,GRHL2,CTNNB1,THRA,SOX9,GPSM2,SAV1,LTA4H,NFIB,FOXA1 |
| 1.032e-03 | -6.88 | antigen processing and presentation of exogenous peptide antigen | biological process | GO:0002478 | 170 | 41 | 16441 | 2455 |
UNC93B1,KIF3C,SEC61G,HLA-E,PSME2,HLA-F,KLC2,PSMD7,TAP1,PDIA3,KIF23,PSMD10,RACGAP1,PSME1,KIF2C,KIF26A,HLA-A,CALR,PSMD1,AP1M2,PSMC2,DNM2,KIF22,HLA-C,CTSD,LGMN,PSMA5,SEC23A,SEC61B,PSMB4,KIF11,PSMA4,CTSL,DCTN6,HLA-B,TAPBP,PSMD3,CTSV,ITGAV,CENPE,PSMC1 |
| 1.032e-03 | -6.88 | negative regulation of cell cycle phase transition | biological process | GO:1901988 | 170 | 41 | 16441 | 2455 |
PSME2,CTDSPL,PSMD7,TP53,PSMD10,PSME1,FANCI,IER3,TP73,SUSD2,CCND1,E2F7,RB1,CCNA2,PSMD1,PTEN,DACT1,PSMC2,FBXO7,H2AFY,BRD7,CDKN1B,BUB1,KANK2,CTDSP2,PSMA5,PLK1,PSMB4,CDC20,RGCC,PSMA4,CDK1,JADE1,PSMD3,OVOL1,PKD2,FHL1,UBE2C,MIIP,PSMC1,CTDSP1 |
| 1.034e-03 | -6.87 | SOCS1 (suppressor of cytokine signaling 1) | protein interactions | 8651 | 62 | 20 | 16036 | 2547 |
TRIM8,TCEB2,PIK3R1,TP53,ERBB2,TEC,FLT3,EGFR,RASA1,IRS2,FYN,INSR,IGF1R,JAK1,PTEN,AXL,CSF1,TUBG1,MAP3K5,JAK3 |
| 1.035e-03 | -6.87 | negative regulation of intracellular protein transport | biological process | GO:0090317 | 94 | 26 | 16441 | 2455 |
TXN,ERLEC1,BAG4,NFKBIE,THRA,DMTN,LITAF,RAB23,PSMD10,BARD1,APC2,NOV,SP100,BMP7,CABP1,WWTR1,NFKBIA,UBE2J1,DAB2IP,PKD2,MDFIC,YOD1,MAPK7,PKIA,MDFI,CHP1 |
| 1.036e-03 | -6.87 | MODULE_378 | MSigDB lists | MODULE_378 | 399 | 81 | 17758 | 2588 |
ACVR1,AASS,MRPS15,TP53,MAPK4,CCNL1,NANS,BAIAP3,CMTM6,C1orf116,RNF220,CYP1A1,METTL7A,PAQR5,ESPN,EPB41L4B,PDE4D,SCARA3,TUBA4A,ATG4D,TMCC2,TDP1,TCEB2,LAP3,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRIM7,KDM4D,AMZ2,PI4K2B,PTGS2,NEIL1,MPRIP,PLEKHG1,RNASEL,RRAGD,LMTK3,CDH22,FAM169A,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,C9orf69,CDK16,TMEM62,CNOT6L,FAR2,CITED2,FAIM,ITM2C,EEF1D,AMOTL2,MOB4,HMGN5,TBC1D8B,ADCK3,FMN1,MICB,FURIN,PIP4K2C,BCL2L13,FOS,BSDC1,PTPRF,FUCA1,CD8A,CSF1,WDR19,S100A5,FGD6,NXPH4,MAL2,GEM,TMEM120A,C17orf75,PKIA |
| 1.037e-03 | -6.87 | FoxO signaling pathway | KEGG pathways | hsa04068 | 134 | 35 | 6908 | 1076 |
PRKAA2,KLF2,FOXO6,SLC2A4,PRKAA1,SOD2,TGFBR1,CCNB1,CCND1,IGF1R,PTEN,SGK3,PLK4,BCL6,PIK3CA,CDKN1B,SGK1,MAPK11,PIK3CD,RAG1,CDKN2D,PLK1,SIRT1,AKT1,PIK3R1,EGFR,GABARAPL1,IRS2,INSR,PRKAG2,CCNB3,PLK2,MAPK13,CCNB2,MAPK12 |
| 1.037e-03 | -6.87 | positive regulation of protein localization to plasma membrane | biological process | GO:1903078 | 35 | 13 | 16441 | 2455 |
KIF5B,SORBS1,ITGA3,AKT1,PIK3R1,DLG1,PRKCI,EZR,PLS1,GPER1,ARF6,ARHGEF16,STX3 |
| 1.037e-03 | -6.87 | positive regulation of protein localization to cell periphery | biological process | GO:1904377 | 35 | 13 | 16441 | 2455 |
KIF5B,SORBS1,ITGA3,AKT1,PIK3R1,DLG1,PRKCI,EZR,PLS1,GPER1,ARF6,ARHGEF16,STX3 |
| 1.039e-03 | -6.87 | CYCLIN | smart domains | SM00385 | 37 | 14 | 9131 | 1455 |
CCNE2,CCNC,CCNI,CCND1,RB1,CCNA2,CCNB3,RBL1,CCNO,CCNJL,CCNL1,CCNF,CCNB1,CCNB2 |
| 1.039e-03 | -6.87 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A | 843 | 155 | 17758 | 2588 |
UNKL,SIGIRR,AGRN,TMEM86B,ATP8A1,CACNA2D2,GATA3,FAM101B,CA8,SH3KBP1,EPDR1,LYPD5,ANKS6,GRHL1,ZCCHC12,ELF5,CAPG,STEAP2,AOX1,NEB,RASGRP1,SMAGP,CYP1B1,LOC81691,CD55,FOPNL,ERP44,ICMT,LDB2,PNKD,CYP4F3,ARHGEF26,EDNRA,ENPP1,PI4K2B,KCNMB4,KLF12,RBM47,LIMK1,NKD1,RAB11FIP1,TTC9,GLA,APBA2,TRAF5,NRGN,RASA2,ASL,ISYNA1,DHRS3,PDXDC1,TTYH3,MYO5C,LYPD3,BDH1,SLC30A6,PRKCI,CACNA1D,C10orf54,TSPAN33,ABCC1,SOCS5,SNX7,GCC2,TBC1D8B,DCHS1,BCL2L13,PCTP,AMDHD1,STEAP1,RASGRP2,BCAR3,MOSPD3,NAAA,SLC4A4,COL13A1,ITGA7,C1orf21,RAB31,DYSF,JAK3,TOB1,PLA2G4A,SLC25A24,KCNAB3,IRX4,KBTBD11,NUDT12,DDR1,TNFSF9,KCTD9,SDF4,IER3,MUC16,RNF220,SRPX,CDH1,BCL6,TAX1BP3,LMAN1,GM2A,MYO5B,DOCK4,CAMSAP3,KREMEN2,SYNE2,PRKCQ,RAB38,ITPR3,DOCK5,MYL12A,HSF4,TAPBP,STK38,MAOA,PLXND1,MLKL,SLC25A30,COBL,CTHRC1,PCOLCE,ARHGEF3,ANO9,FGF19,SH2D4A,ITGA2B,TMEM63A,KIF5B,RASSF8,TAF1B,IRAK1,MCF2L,KNDC1,ZDHHC13,IL17RA,ACTA2,ADAM15,C2orf72,MXD3,KLF9,MYO5A,ATP2B1,PDGFC,LCA5,B3GNT2,IFITM3,NR3C1,PIK3R1,FOS,SPAG1,DGKE,RND3,PGRMC1,ARRB1,ARSB |
| 1.043e-03 | -6.87 | stomach-carcinoma-mucinous_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-mucinous_adenocarcinoma | 13 | 7 | 17775 | 2585 |
ERBB2,PTEN,EGFR,MSH6,PIK3R1,PIK3CA,TP53 |
| 1.043e-03 | -6.87 | mucinous_adenocarcinoma | COSMIC cancer mutations | mucinous_adenocarcinoma | 13 | 7 | 17775 | 2585 |
ERBB2,PTEN,EGFR,MSH6,PIK3R1,PIK3CA,TP53 |
| 1.043e-03 | -6.87 | PRL | COSMIC cancer mutations | PRL | 13 | 7 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,RET,PIK3CA,PRKAR1A |
| 1.043e-03 | -6.87 | pituitary-adenoma-PRL | COSMIC cancer mutations | pituitary-adenoma-PRL | 13 | 7 | 17775 | 2585 |
GNAS,CDKN2C,RB1,CTNNB1,RET,PIK3CA,PRKAR1A |
| 1.044e-03 | -6.86 | DELYS_THYROID_CANCER_DN | MSigDB lists | DELYS_THYROID_CANCER_DN | 223 | 50 | 17758 | 2588 |
WASF3,COL9A3,ALDH6A1,GCAT,TSC22D3,NUCB2,NUP62CL,FBLN1,TSPAN7,SNTA1,BMP2,MDM1,ADD3,TGFBR3,SRPX,CYR61,GPC3,FOSB,AOX1,ALDH7A1,EPB41L4B,NCAM1,CITED2,NEB,CTH,FBLN5,ALDH2,HSPA12A,PRKCQ,LDB2,FOS,PLCH1,ENPP1,HLF,PROM1,SLC4A4,FAAH,FGFR2,WFS1,MATN2,ITPR1,CLMN,TLE1,FHL1,TBC1D4,STARD13,LIFR,TOB1,CYBRD1,CSRP2 |
| 1.045e-03 | -6.86 | Insulin signaling pathway | KEGG pathways | hsa04910 | 139 | 36 | 6908 | 1076 |
PRKAA2,ACACB,SORBS1,SLC2A4,INPPL1,TRIP10,PRKAA1,FLOT1,CALM3,PRKACA,CALM2,SHC3,PRKCI,PIK3CA,GYS1,PIK3CD,PPP1CA,PHKA2,FLOT2,PHKG2,AKT1,CALM1,PIK3R1,PYGL,PRKAR2B,ELK1,CBL,RHEB,SOCS3,PTPRF,IRS2,TSC1,PRKAG2,INSR,PPP1CB,PRKAR1A |
| 1.045e-03 | -6.86 | Insulin signaling pathway | KEGG pathways | ko04910 | 139 | 36 | 6908 | 1076 |
PRKAA2,ACACB,SORBS1,SLC2A4,INPPL1,TRIP10,PRKAA1,FLOT1,CALM3,PRKACA,CALM2,SHC3,PRKCI,PIK3CA,GYS1,PIK3CD,PPP1CA,PHKA2,FLOT2,PHKG2,AKT1,CALM1,PIK3R1,PYGL,PRKAR2B,ELK1,CBL,RHEB,SOCS3,PTPRF,IRS2,TSC1,PRKAG2,INSR,PPP1CB,PRKAR1A |
| 1.050e-03 | -6.86 | lipid binding | molecular function | GO:0008289 | 642 | 124 | 16491 | 2452 |
PLA2G4A,DOC2A,MTM1,TRIP10,IQGAP1,DGKA,P2RX7,RASGRP3,ITPR2,SYTL4,CDIPT,MVB12B,SNX9,CYP26A1,ZFYVE9,SYTL2,ZFYVE16,OSBPL3,PAQR5,FABP6,PASK,SNX16,DAB2IP,ACOX2,OSBPL7,PACSIN1,TIAM1,SNX10,HSPA2,S100A13,RASGRP1,SNX8,SOAT1,CD55,MCTP1,MARK1,AKT1,SYP,ESYT1,ITPR3,SNX12,VCP,SEC14L2,OSBPL2,PTGS2,ATP1A1,DNM1L,WIPI1,AXL,INPP4B,PIK3C2B,ANXA9,SYT13,CHPT1,PXDC1,NRGN,STARD13,NR3C2,TC2N,ABCA1,ANXA11,ANXA3,PACSIN2,ARAP3,TRAF2,MCTP2,SELL,RACGAP1,PLD2,TEC,CRABP2,APBA1,FAM21C,RBP7,SNX13,WDFY1,SNX18,PTEN,MCF2L,SGK3,BAX,PRKCI,ATP8B1,PLEKHF1,CADPS2,TTPA,SYTL3,CCDC88A,SNX7,PAQR7,CYP26B1,ACBD5,ARAP2,PSMB4,NR3C1,RAPGEF2,AMER1,PPARA,PYGL,NPC2,PCTP,CPTP,STX3,RASGRP2,EPN3,LDLRAP1,SEC14L4,SYT7,DBI,PLA2G15,ITPR1,ARAP1,PGRMC1,DYSF,PITPNA,GPER1,PLD1,WDR45B,APOL2,MELK,SNX30,ESYT2,ABCG1,PROM2 |
| 1.051e-03 | -6.86 | myxofibrosarcoma | COSMIC cancer mutations | myxofibrosarcoma | 20 | 9 | 17775 | 2585 |
GNAS,RB1,CTNNB1,CDH1,PTEN,PIK3CA,TP53,IDH1,EGFR |
| 1.051e-03 | -6.86 | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma-myxofibrosarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma-myxofibrosarcoma | 20 | 9 | 17775 | 2585 |
GNAS,RB1,CTNNB1,CDH1,PTEN,PIK3CA,TP53,IDH1,EGFR |
| 1.053e-03 | -6.86 | lung-carcinoma-carcinosarcoma | COSMIC cancer mutations | lung-carcinoma-carcinosarcoma | 7 | 5 | 17775 | 2585 |
ERBB2,CTNNB1,EGFR,PIK3CA,TP53 |
| 1.054e-03 | -6.86 | negative regulation of macromolecule metabolic process | biological process | GO:0010605 | 2342 | 400 | 16441 | 2455 |
TXN,PPP4R4,TRIM24,LGR4,IBTK,TSC22D3,DNAJC3,XIAP,GATA3,PSME1,MORF4L2,CCNB1,BARD1,RIC1,PHF1,TP73,CALM2,CDKN2C,PSMD1,CTGF,ZFP36,RGS3,FOSB,IRF2,CRY2,ZBTB18,TIPARP,APOBEC3G,SMARCA2,TNIP1,PBK,UXT,CDYL,TFAP2C,AGO4,PRKAR2B,LOXL2,PIF1,AURKB,POR,AHRR,PIAS3,ENPP1,CAMK2N2,LIMK1,TRAF3IP1,PPP2R4,PRDM5,NOD2,HDAC1,SERPINB6,EIF4EBP2,SERPINI1,SPRY4,HSPB1,F2RL1,E2F8,INPPL1,CDKN1C,SOX9,RAB23,SH3RF2,MECOM,ELF3,MARCH8,TFAP4,CALR,PAIP2B,BHLHE41,FBXO7,MSH2,DAPK1,SORL1,DLX4,NUP85,SOCS5,SALL4,CALM1,FHL2,WHSC1,EPHA1,ILK,KDM3A,PSMA4,NFIB,FAS,AP1AR,PRKAG2,ETS2,HTT,SEMA4D,NAB2,PIAS2,SFMBT1,NR4A2,STK39,EFNA1,PER3,CBX5,SERPINB1,NUP58,RPS6KA3,XDH,EGLN1,IRF1,ELK4,SPRED1,TCF25,S100A11,THRA,INPP5D,RPS6KA1,CAST,SUZ12,PTTG1,WDTC1,CCND1,CD46,APLP2,SP100,DACT1,CDKN1B,DAB2IP,PDE4D,DLG3,CDKN2D,FLOT2,MYT1,NR2C1,RNF169,CAMSAP3,APOBEC3D,DMTN,DRAP1,RAD17,PKMYT1,H2AFV,SNX12,NFIX,FYN,WFS1,CORO1C,WWTR1,STAT1,KLF5,NRG1,RGS14,CBX7,PRKAR1A,FARP1,TNRC6C,NKX3-1,DEPDC1,TRAF2,APOBEC3H,PKN1,ZNF219,GSTP1,TIPRL,FGF19,SIX4,WWP2,CTNNBIP1,SNTA1,E2F7,PDCD10,ITGB8,IRAK1,RNF128,PTEN,GPC3,CST3,BAX,ATP8B1,TMBIM6,WWP1,ERCC2,CITED2,CNOT6L,RAG1,GFI1,SPRY2,TRIM62,NCOA2,CRTAP,MSH6,TGIF1,FURIN,CDK5RAP1,PITX2,TIMP3,FGFR2,PRDX3,NR1D2,ACVRL1,TBX18,NR4A3,SERPINB5,ITGAV,GPER1,HMGA1,LRRK1,NUP37,OSR1,SHOX2,CPEB2,SRSF9,JARID2,SIGIRR,CASP3,ST13,CRYM,CNOT8,SUDS3,LMCD1,NDRG2,HDAC6,PDGFB,ERP29,NUP210,CTNNB1,SIVA1,PSMC2,PASK,MITF,DLG1,DUSP10,MYBL1,CYP1B1,PLK1,THRB,CD55,KCNIP3,CXXC5,TRIM8,ASXL1,ITCH,CBX6,EZR,PRKRA,OPTN,NEIL1,KLF12,KLF11,PSMC1,RUNX2,LMTK3,SERPINE2,UBASH3B,DNAJB2,PDCL,PSMD7,CALM3,SORBS3,HES2,FBLN1,DUSP5,BMP2,RB1,TIMP1,IGF1R,GATA2,PAK2,FNIP1,MDFIC,PIM1,RFX5,ETV7,PSMA5,MDFI,ELK3,HMG20B,EIF2AK1,RANBP9,EGFR,CDK5R1,NUDT16,TSC1,PLPP3,NFKBIA,NLRC5,YOD1,JAK3,CDAN1,TOB1,CTBP1,IFI6,RARG,DRD1,GAS2L1,NF2,FOXM1,PSME2,CTDSPL,TP53,P2RX7,TDRKH,OSR2,BAHD1,PATL2,MXD1,SYTL2,PER2,SAP130,SVBP,SETDB2,BCL6,SMO,TWIST1,NOTCH3,NFKB2,CTDSP2,CHP1,SIRT1,TIMP2,BAG4,ERLEC1,AKT1,CDC20,ERBB2IP,DUSP4,DAG1,C3orf33,ARHGAP35,SOCS3,HSF4,MYPOP,DNAJC10,IDE,PTPRJ,RBL1,STAT6,STK38,PSMD3,PEX2,OVOL1,PTBP3,TLE1,IRF7,CBX4,CTDSP1,ARFGEF3,GLIS3,PINK1,CPEB4,DAP,SERPINB9,PSMD10,AES,NKRF,TRIB2,FZD6,SH2D4A,HDAC9,CD109,IRF2BPL,FOXP2,TAF1B,BMP7,UBE2J1,TFAP2A,H2AFY,BRD7,TRIM21,BUB1,KANK2,HEXIM2,MXD3,IQGAP3,DUSP1,NFE2L3,HES1,PSMB4,WNT10B,IFITM3,PLAUR,GCLC,PPARA,PRICKLE1,RUNX3,COL7A1,FXR2,BBS2,MAPK8IP1,LEMD2,CNOT2,BANK1,SWAP70,SERPINA1,SPINT2,NMI,E2F1,ARRB1,SOX8,NDFIP1,UBE2C,AHR,HIPK3,ZBTB33,PKIA |
| 1.056e-03 | -6.85 | regulation of protein catabolic process | biological process | GO:0042176 | 430 | 88 | 16441 | 2455 |
DLGAP5,PSME2,CUL4B,CUL1,PSME1,CCNB1,PRKACA,SNX9,BARD1,APC2,BCAP31,RIC1,RAD23A,IER3,PSMD1,DACT1,PSMC2,CDKN1B,DAB2IP,OSBPL7,TIPARP,PLK1,VPS11,TIMP2,ERLEC1,AKT1,ITCH,PBK,USP18,CDC20,EZR,RNF19B,SNX12,CDK1,VCP,FYN,PLK2,PSMD3,NKD1,NRG1,PSMC1,PINK1,GGA1,DNAJB2,SH3D19,SOX9,ASB9,PSMD7,PSMD10,TRIB2,PPP2R3A,RB1,RNF128,TIMP1,CTSC,PTEN,GPC3,CST3,UBE2J1,SORL1,BUB1,USP38,USP1,MYLIP,PSMA5,SOCS5,PSMB4,WNT10B,USP31,GCLC,NUB1,FURIN,PRICKLE1,PSMA4,EGFR,GPLD1,USP6,TIMP3,FAM83D,AURKA,YOD1,CENPE,CD81,NDFIP1,UBE2C,ESPL1,USP16,USP43 |
| 1.057e-03 | -6.85 | response to hypoxia | biological process | GO:0001666 | 267 | 59 | 16441 | 2455 |
CASP3,PINK1,NKX3-1,SLC2A4,HSP90B1,EPAS1,SLC2A8,NDRG1,PRKAA1,TP53,ITPR2,CCNB1,PDGFB,ETS1,ICAM1,LMNA,BMP2,CAPN2,CYP1A1,TGFBR3,ADORA1,IRAK1,P4HB,PTEN,BMP7,VASN,CST3,CDKN1B,AHCY,TWIST1,ERCC2,ARNT2,CITED2,EGLN3,HP1BP3,SIRT1,ADAM17,RHOA,AKT1,TCEB2,PPARA,RGCC,PRKCQ,SLC11A2,LOXL2,ATP1B1,PDK3,SOCS3,EDNRA,PTGS2,PLOD2,ITPR1,E2F1,UBE2D2,NR4A2,CPEB2,ARNT,DRD1,EGLN1 |
| 1.057e-03 | -6.85 | VACUOLAR_TRANSPORT | MSigDB lists | VACUOLAR_TRANSPORT | 13 | 7 | 17758 | 2588 |
NAGPA,ZFYVE16,ARSB,RHOB,ATG4D,M6PR,ATG4A |
| 1.057e-03 | -6.85 | YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | MSigDB lists | YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | 13 | 7 | 17758 | 2588 |
TNS1,TRAM2,LTBP2,FRMD4A,DSE,CALD1,DCHS1 |
| 1.057e-03 | -6.85 | LEE_SP4_THYMOCYTE | MSigDB lists | LEE_SP4_THYMOCYTE | 13 | 7 | 17758 | 2588 |
NR4A2,EGR3,PDE4D,DUSP4,SERPINE2,SPRY2,IER3 |
| 1.057e-03 | -6.85 | MODULE_464 | MSigDB lists | MODULE_464 | 13 | 7 | 17758 | 2588 |
ALDH3B1,ALDH7A1,ALDH5A1,ALDH6A1,ALDH3A2,ALDH1A3,AOX1 |
| 1.062e-03 | -6.85 | haematopoietic_and_lymphoid_tissue-skin-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | 58 | 18 | 17775 | 2585 |
AKT1,ASXL1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,PIK3CA,SMO,JAK3 |
| 1.067e-03 | -6.84 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | MSigDB lists | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | 20 | 9 | 17758 | 2588 |
CALR,HLA-B,SEC23A,HLA-F,TAP1,ERAP1,PDIA3,HLA-C,HLA-A |
| 1.068e-03 | -6.84 | GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 185 | 43 | 17758 | 2588 |
CDK17,ARAP3,NFKBIE,PPP1R12A,CUL4B,SERPINB9,TMX4,HERC5,F11R,SAMD9,DSE,SIRPA,SP100,SNX18,CASC4,FRYL,PHTF1,ECE1,CNOT6L,CNPY3,SNX10,XKR8,DUSP1,MX1,CDKN2AIP,TACC1,LPGAT1,SERTAD3,KCTD20,ATP10D,SPAG1,LCP1,CRISPLD2,CRTC2,MAPKAPK2,ZNF641,STK38,SIPA1L1,CAB39,ARHGAP4,SERPINB1,PTGES,DEF6 |
| 1.072e-03 | -6.84 | cerebral cortex development | biological process | GO:0021987 | 104 | 28 | 16441 | 2455 |
EMX1,RHOA,ADGRG1,TACC1,ASPM,GRIN1,TFAP2C,CNTNAP2,BBS2,EGFR,CDK5R1,FOXP2,MDK,TSC1,FAT4,CTNNB1,TACC2,KIF14,LHX6,SMO,BAX,DIXDC1,DAB2IP,ZBTB18,WDR62,NDE1,SEMA3A,BTBD3 |
| 1.073e-03 | -6.84 | CRMPs in Sema3A signaling | REACTOME pathways | R-HSA-399956 | 16 | 8 | 8202 | 1235 |
DPYSL5,FYN,DPYSL2,PLXNA1,DPYSL4,SEMA3A,CDK5R1,DPYSL3 |
| 1.073e-03 | -6.84 | Polo-like kinase mediated events | REACTOME pathways | R-HSA-156711 | 16 | 8 | 8202 | 1235 |
PLK1,WEE1,FOXM1,MYBL2,PKMYT1,CCNB1,CCNB2,CDC25C |
| 1.075e-03 | -6.84 | Furin-like_Cys-rich_dom | interpro domains | IPR006211 | 7 | 5 | 18293 | 2672 |
ERBB2,INSR,ERBB3,IGF1R,EGFR |
| 1.075e-03 | -6.84 | Rcpt_L-dom | interpro domains | IPR000494 | 7 | 5 | 18293 | 2672 |
ERBB2,INSR,ERBB3,IGF1R,EGFR |
| 1.077e-03 | -6.83 | WARTERS_RESPONSE_TO_IR_SKIN | MSigDB lists | WARTERS_RESPONSE_TO_IR_SKIN | 72 | 21 | 17758 | 2588 |
DDB2,FRMD4A,TMTC3,GDF15,FAM198B,MICALL2,ZNF219,SESN1,ALCAM,FAS,BTG3,E2F7,CES2,ICAM5,FDXR,DRAM1,SERPINB5,ETV7,TMEM173,GM2A,WDR63 |
| 1.085e-03 | -6.83 | CELL_CYCLE_PHASE | MSigDB lists | CELL_CYCLE_PHASE | 169 | 40 | 17758 | 2588 |
ACVR1,USH1C,DLGAP5,CDKN1C,CIT,NDC80,CUL1,KIF2C,NPM2,CDKN2C,RB1,CCNA2,NEK2,CDKN1B,KIF22,BUB1,KNTC1,GFI1,CDKN2D,HSPA2,MPHOSPH9,SMC4,REC8,PLK1,ZWINT,NUSAP1,RAD17,PKMYT1,ANLN,KIF11,CDC25C,CDCA5,E2F1,MAP3K11,AURKA,KPNA2,CENPE,UBE2C,ESPL1,RAD21 |
| 1.087e-03 | -6.82 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | 196 | 45 | 17758 | 2588 |
ARAP3,BLVRB,SOD2,ASAH1,EFHD2,FAM198B,ARHGEF40,SIRPA,IER3,ARHGEF10L,APLP2,TIMP1,RALB,BCL6,SGK1,RAB20,MTMR11,ALDH3A2,TMBIM1,CKAP4,TUBA4A,CYP1B1,TGIF1,SAT1,PYGL,BLVRA,DOCK5,CRISPLD2,TMEM164,ALDH3B1,SERPINA1,HPSE,RCBTB2,ZDHHC7,ARRB1,EIF4EBP2,KLF11,SERPINB6,REEP4,SLC31A2,LTA4H,AHR,CPPED1,PCSK5,CD33 |
| 1.087e-03 | -6.82 | GSE17721_12H_VS_24H_GARDIQUIMOD_BMDM_UP | MSigDB lists | GSE17721_12H_VS_24H_GARDIQUIMOD_BMDM_UP | 196 | 45 | 17758 | 2588 |
CCDC109B,IL15RA,FAM129B,IQGAP1,ABCG2,IRX4,GPSM2,CTNNB1,IL6ST,ZFP36,PAPSS1,SGK1,IL17RA,RTKN2,CTTN,PARP9,P2RX4,SUN2,HMGN5,SH3BGRL,PTPN9,STAU2,S100A4,CDYL,LITAF,FURIN,NUSAP1,PKMYT1,ESYT1,CD40,ASB13,C18orf8,ENDOD1,NCOA3,TMEM50B,SEMA4D,ZFP30,NIPSNAP3A,ZDHHC20,HDAC1,IRF7,SAMD8,ICOSLG,L1CAM,RPS6KA3 |
| 1.087e-03 | -6.82 | ATACTGT,MIR-144 | MSigDB lists | ATACTGT,MIR-144 | 196 | 45 | 17758 | 2588 |
CCNE2,AGRN,LGR4,ARFGEF1,GATA3,ETS1,NRP2,APPBP2,TFAP4,ZFX,SS18,HSF2,ALDH1A3,FOSB,AHCY,PIM1,PDE4D,ACSL4,SLC12A2,MYT1,CCDC88A,ATP2B1,NR3C1,PFKFB2,PTPN9,ACBD3,PANK1,PPARA,CALCRL,KBTBD8,FNDC3A,PTGFRN,SP4,NIN,CACHD1,DGCR2,NGFRAP1,CDK19,TBX1,UBE2D2,GLCCI1,LIFR,E2F8,CPEB2,CBX4 |
| 1.089e-03 | -6.82 | SANSOM_WNT_PATHWAY_REQUIRE_MYC | MSigDB lists | SANSOM_WNT_PATHWAY_REQUIRE_MYC | 58 | 18 | 17758 | 2588 |
CCNE2,TP53,CUL1,TCF7,TNFRSF19,FZD6,FZD7,PTGS2,RABEP2,BMP7,NKD1,BAX,E2F1,TNFRSF12A,IGFBP2,TIAM1,SP5,FOXA1 |
| 1.089e-03 | -6.82 | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | MSigDB lists | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | 58 | 18 | 17758 | 2588 |
MAP3K3,EPAS1,RPS6KA1,TRAF2,ZFAND5,CARD10,BCL10,CCND1,NCOA3,CTNNB1,HTT,PPP2R4,E2F1,ARRB1,IRF7,NOTCH3,TFG,NR2C2 |
| 1.089e-03 | -6.82 | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_TBH | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_TBH | 58 | 18 | 17758 | 2588 |
CDKN1C,ITGA6,EZR,BCL2L1,ETS1,CAPN2,IGF1R,ETS2,HTT,IL6ST,STAT6,MYLK,BMP1,E2F1,PPP1CA,CTTN,CPE,HSPA2 |
| 1.089e-03 | -6.82 | ISSAEVA_MLL2_TARGETS | MSigDB lists | ISSAEVA_MLL2_TARGETS | 58 | 18 | 17758 | 2588 |
COL9A3,IGFBP6,CRIP2,IL18,LOXL2,ALCAM,ELF3,HDAC9,HPSE,AXL,CD9,PRKCDBP,TAGLN2,FHL1,LOXL1,SLC16A5,L1CAM,SEMA3B |
| 1.097e-03 | -6.82 | V$ELF1_Q6 | MSigDB lists | V$ELF1_Q6 | 229 | 51 | 17758 | 2588 |
KIF3C,CMAS,PAX6,PSME2,IQGAP1,XIAP,FAM134A,RASGRP3,CD274,ITPR2,CAMK1D,PKN1,BAHD1,DPP8,SIX4,XPR1,ZNF687,ADD3,STIM1,SHC3,MITF,SORL1,TWIST1,PIK3CD,ACSL4,NCAM1,CNOT6L,PLCB2,TBC1D10B,FBLN5,PTPRH,SAT1,CALCRL,TFAP2C,ARHGDIB,TXK,TBC1D17,PLEKHH2,KLF12,STAT6,CSF1,MADD,MAP3K11,PRDM5,VSIG10,CTNND1,CTSA,ARPC2,C1orf43,JARID2,NR2C2 |
| 1.099e-03 | -6.81 | RPS6KA1 (ribosomal protein S6 kinase, 90kDa, polypeptide 1) | protein interactions | 6195 | 80 | 24 | 16036 | 2547 |
GRN,NR4A1,MPP1,RPS6KA1,SRSF5,FOS,MXD1,VCP,GNS,TSC1,CARHSP1,RPS6KA2,CASP7,NFKBIA,MITF,NR4A3,CDKN1B,NR4A2,TOB1,L1CAM,SYK,RPS6KA3,CAPN1,EEF1D |
| 1.100e-03 | -6.81 | microtubule organizing center attachment site | cellular component | GO:0034992 | 7 | 5 | 17570 | 2579 |
SUN1,SUN3,SUN2,SYNE3,SYNE2 |
| 1.100e-03 | -6.81 | LINC complex | cellular component | GO:0034993 | 7 | 5 | 17570 | 2579 |
SUN1,SUN3,SUN2,SYNE3,SYNE2 |
| 1.105e-03 | -6.81 | integral component of nuclear inner membrane | cellular component | GO:0005639 | 13 | 7 | 17570 | 2579 |
LEMD2,SUN1,P2RX4,P2RX7,SUN2,TMEM43,LBR |
| 1.105e-03 | -6.81 | intrinsic component of nuclear inner membrane | cellular component | GO:0031229 | 13 | 7 | 17570 | 2579 |
LEMD2,SUN1,P2RX4,P2RX7,SUN2,TMEM43,LBR |
| 1.105e-03 | -6.81 | condensed chromosome outer kinetochore | cellular component | GO:0000940 | 13 | 7 | 17570 | 2579 |
PLK1,BUB1,CENPE,CCNB1,SPDL1,SKA1,NDC80 |
| 1.106e-03 | -6.81 | organic substance catabolic process | biological process | GO:1901575 | 1534 | 271 | 16441 | 2455 |
GAA,TRIM24,HSPG2,AASS,PNPLA2,DNAJC3,HEXB,FBXO2,CUL1,PSME1,CCNB1,PLA2G16,OAT,CALM2,TYMP,CYP1A1,PSMD1,ZFP36,FUT1,PPP1CA,TINAGL1,ACOX2,APOBEC3G,ERAP2,FBXL16,SPATA18,RNF11,CDA,BNIP3L,MGAM,AGO4,AURKB,CCNF,RNF19B,PNKD,CYP4F3,ENPP1,PLCG1,DHTKD1,ALDH6A1,DHPS,ZNRF3,GNS,RPL39,FBXO7,BDH1,NEK2,FBXL14,PCYOX1,USP1,USP38,STT3B,CTSD,MYLIP,PHKG2,MCCC2,UFD1L,PRODH,CALM1,PYM1,PYGL,PKM,TP53INP2,PSMA4,FBXO10,DCP2,PDE11A,NT5C2,FAAH,AURKA,XDH,PLA2G4A,PTTG1,MVB12B,PRKACA,NUDT12,CYP39A1,EPM2A,DAB2IP,RNASEH2A,PDE4D,PHKA2,LGMN,NAGA,ENPP4,SEC61B,PFKFB2,SAT1,VPS4B,CBL,ZMPSTE24,ALDH3B1,ACAD10,WFS1,WWTR1,PNPLA6,PPP1CB,AREL1,GALK1,HSP90B1,GCAT,BACE1,TRAF2,SDC4,CTSZ,APOBEC3H,PLD2,FBXO6,PNPLA5,WWP2,SGPL1,CAPN2,FUT2,OXCT1,RNF128,CTSC,MGAT1,PTEN,GPC3,FUT8,ECI2,WWP1,CNOT6L,PCCB,ALDH2,SHMT1,NUB1,UBE2A,FBXO9,BLVRA,RPL12,ACADSB,PLA2G15,PGM2L1,ERAP1,ARSB,ACOT7,USP16,CASP3,FAF2,AGRN,GNPDA1,CRYM,CPT2,CNOT8,CUL4B,MCCC1,UBE2Z,HDAC6,SDC1,ECI1,MAGOHB,INPP5E,ENTPD4,DDHD2,PSMC2,CYP1B1,PLK1,USP18,ITCH,RNF165,CCBL2,CDK1,VCP,TRIM9,PLCH1,NEIL1,HPSE,GLA,PPP2R5D,PSMC1,CAPN1,DNAJB2,ASL,PSMD7,CALM3,PFKL,AHCY,NCEH1,ZRANB1,ACAD8,GAD1,PLCB2,PSMA5,CYP26B1,USP31,PDE5A,FBXO8,AMDHD1,DHDH,NUDT16,H1F0,PAPD5,CTSA,YOD1,PLD1,RNF146,FBXW5,USP43,UPF3B,PSME2,P2RX7,PATL2,LPIN3,CYP26A1,RAD23A,CYP4F11,KIF14,FABP6,PLCG2,GOT1,ECE1,ETHE1,GM2A,UPF3A,CTH,CHP1,SIRT1,ERLEC1,AKT1,CDC20,DNAJC10,IDE,ALDH5A1,PAFAH1B3,ABHD12,PSMD3,PEX2,MAOA,CHMP4B,RPL22,LTA4H,PINK1,ENO2,CTSB,JKAMP,CIT,BLVRB,HAL,ERI2,PSMD10,NOTUM,DNAJB9,ADORA1,GALNS,UBE2J1,ABCD1,HMGCL,ALDH7A1,FAH,HMMR,PGM1,PSMB4,GUSB,AMFR,OGDHL,RNPEP,USP6,CTSL,FUCA1,CNOT2,DDAH1,CTSV,UBE2D2,ARRB1,GLB1,ACADM,UBE2C,NDFIP1,SAT2,DIS3L |
| 1.106e-03 | -6.81 | regulation of cellular catabolic process | biological process | GO:0031329 | 599 | 117 | 16441 | 2455 |
DLGAP5,CNOT8,PNPLA2,PSME2,TP53,CUL1,P2RX7,PSME1,BCL2L1,CCNB1,PRKACA,SNX9,MAP1LC3B,BCAP31,RIC1,EPM2A,RAD23A,IER3,DAPK2,PSMD1,RALB,ZFP36,PSMC2,DAB2IP,TWIST1,PPP1CA,CTTN,OSBPL7,PLK1,SIRT1,VPS11,TIMP2,TRIM8,AKT1,NRBF2,PBK,USP18,CDC20,BNIP3L,EZR,IDH1,RNF19B,TYSND1,CDK1,VCP,ULK2,IRS2,DNM1L,PLK2,PSMD3,PPP1CB,CHMP4B,PSMC1,LZTS1,ARNT,RRAGD,PRKAA2,PINK1,TNRC6C,SCOC,DAP,SH3D19,DNAJB2,PRKAA1,PSMD7,PSMD10,TRIB2,RB1,TIMP1,RNF128,CTSC,PTEN,CST3,DRAM1,DAPK1,BAX,PLEKHF1,TRIM21,BUB1,USP38,USP1,PIKFYVE,MAPK7,MYLIP,PHKG2,PSMA5,SOCS5,QSOX1,USP31,PSMB4,WNT10B,GCLC,NUB1,PPARA,FURIN,PIP4K2C,PRICKLE1,TP53INP2,PSMA4,PLIN5,USP6,GPLD1,TIMP3,INSR,PRKAG2,SH3BP4,AURKA,CTSA,CENPE,FZD5,CD81,UBE2C,TOB1,ESPL1,USP16,USP43,EGLN1 |
| 1.107e-03 | -6.81 | MODULE_485 | MSigDB lists | MODULE_485 | 49 | 16 | 17758 | 2588 |
FADS2,DLGAP5,SSH1,NQO1,GRIK2,MYBL2,GLT8D2,ARHGEF16,ELF3,CCNA2,PCNA,FCHO1,BDH1,AURKA,BUB1,HOOK1 |
| 1.107e-03 | -6.81 | TBK1.DN.48HRS_DN | MSigDB lists | TBK1.DN.48HRS_DN | 49 | 16 | 17758 | 2588 |
CTNNAL1,PLEKHJ1,IL13RA1,PRKCQ,DUSP4,GTF2A2,H2AFV,CDK1,PDHX,IER3,ANKRD10,PDGFA,PAFAH1B3,RALB,DCK,INPP4B |
| 1.107e-03 | -6.81 | regulation of binding | biological process | GO:0051098 | 262 | 58 | 16441 | 2455 |
CTHRC1,TXN,NKX3-1,ADD1,HJURP,LFNG,ARHGEF7,TRAF2,HABP4,FLOT1,NES,GATA3,TGFBR1,AES,PRKACA,PDGFB,PER2,CTNNBIP1,BMP2,TFAP4,APLP2,TGFBR3,SP100,RALB,NEK2,SMO,BAX,ADAM15,TMBIM6,SORL1,DAB2IP,TWIST1,ERCC2,IFIT1,WNT3A,MDFI,ZNF462,PLK1,EPB41L5,HES1,RAPGEF2,PLAUR,AMFR,PPARA,AURKB,NFIB,EBF2,KDM4D,PTPRF,LDLRAP1,PLK2,NFKBIA,E2F1,AURKA,ARRB1,NRG1,PLXND1,TMEM173 |
| 1.117e-03 | -6.80 | UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN | MSigDB lists | UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN | 36 | 13 | 17758 | 2588 |
BMP2,KLF2,PTGS2,CYR61,NR4A1,ZFP36,NDRG1,NR4A3,NR4A2,EGR3,GEM,CITED2,DUSP1 |
| 1.119e-03 | -6.80 | LIN_NPAS4_TARGETS_UP | MSigDB lists | LIN_NPAS4_TARGETS_UP | 148 | 36 | 17758 | 2588 |
PRKAA2,EPAS1,ARHGEF7,RNF182,GMCL1,MRAS,NANS,FAM81A,CDK14,MARCH8,B3GALNT1,MKRN3,LYPD6,DDHD2,KIAA0319,CDKN1B,SGK1,SLC35A1,SCN3A,RAB3B,LPGAT1,FBXO8,C2orf69,RAB2B,BSDC1,MAGED2,PPP2R4,PNPLA6,ZDHHC7,CHMP4B,ZBTB6,TMEM8B,B4GALT3,PKIA,ACOT7,RPS6KA3 |
| 1.121e-03 | -6.79 | PID_P73PATHWAY | MSigDB lists | PID_P73PATHWAY | 77 | 22 | 17758 | 2588 |
SIRT1,CCNE2,BIN1,PLK1,ITCH,GDF15,JAG2,CCNB1,S100A2,TP53I3,CDK1,FAS,TP73,RB1,CCNA2,JAK1,SERPINA1,BAX,BUB1,MAPK11,FLOT2,IL1RAP |
| 1.123e-03 | -6.79 | HS-GAG biosynthesis | REACTOME pathways | R-HSA-2022928 | 31 | 12 | 8202 | 1235 |
HS6ST1,SLC35D2,AGRN,HSPG2,GPC3,SDC4,HS3ST3B1,SDC1,NDST3,EXT2,GLCE,HS6ST3 |
| 1.126e-03 | -6.79 | nephron tubule morphogenesis | biological process | GO:0072078 | 66 | 20 | 16441 | 2455 |
HES1,LGR4,FMN1,DCHS1,SOX9,GATA3,ILK,IRX3,BMP2,CTNNBIP1,CTNNB1,FAT4,NPNT,GPC3,DLG1,PKD2,TACSTD2,OSR1,SOX8,ADAMTS16 |
| 1.135e-03 | -6.78 | positive regulation of defense response | biological process | GO:0031349 | 391 | 81 | 16441 | 2455 |
LAMP1,UNC93B1,TRIM5,IL15,RPS6KA1,PSME2,CUL1,PSME1,IL18,ITPR2,PRKACA,CALM2,PSMD1,RPS6KA2,IL6ST,PSMC2,PLCG2,NFKB2,SCARA3,LGMN,SMAGP,RASGRP1,RIPK2,TNIP1,ITCH,PTGER4,F12,ITPR3,DUSP4,PTGS2,FYN,GPRC5B,CDK19,PSMD3,NOD2,IRF7,MAPK13,F2RL1,PSMC1,PPP2R5D,DDX58,HSP90B1,TAB3,CTSB,HLA-E,PSMD7,CALM3,PSMD10,IRAK1,PIK3AP1,PAK2,IL17RA,MAPK11,MAPK7,MAP3K7,CNPY3,SYK,PSMA5,KLK5,PLSCR1,PSMB4,MAPKAPK3,CALM1,ELK1,FOS,PSMA4,TXK,BCL10,CTSL,MAPKAPK2,PVRL2,PELI2,NFKBIA,ITPR1,UBE2D2,NLRC5,OSMR,KLK7,IFIH1,RPS6KA3,TMEM173 |
| 1.137e-03 | -6.78 | BAND41 | prints domains | PR00935 | 25 | 10 | 4759 | 661 |
EPB41L5,FARP1,FRMD4A,NF2,EZR,EPB41L4B,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 1.140e-03 | -6.78 | TGCGCANK_UNKNOWN | MSigDB lists | TGCGCANK_UNKNOWN | 518 | 101 | 17758 | 2588 |
CCNI,SPRED1,DYNLRB1,SLC2A4,PPP4R4,TCF25,THRA,NDRG1,RALBP1,FLYWCH2,WDTC1,XIAP,TP53I11,MORF4L2,PIGL,PHF1,SLC9A7,CALM2,CYHR1,WDR44,P4HB,PPME1,FOSB,SRR,TMEM143,SERINC2,TUBG1,VAT1,PDE4D,TECR,RASGEF1A,TRAM1,BTBD3,NR2C1,DVL2,FRS3,GPX4,CKS2,TAF5,KIFC2,C12orf65,PKMYT1,ICMT,RNF19B,CAB39,HS3ST3B1,SPRY4,PRIMA1,CBX4,CCDC97,OTUD5,PINK1,PPP1R12A,RBM24,SHPRH,RAB23,CALM3,ADCK5,IFT27,AIP,PDXDC1,TFAP4,PPP1R10,CDK16,PRICKLE4,KCNK5,FAM13B,MSH2,ARVCF,WWP1,MXD3,HEXIM2,GFI1,TTLL1,FAM134C,TMX1,HMMR,TGIF1,RHOA,BCL9,TEF,CALM1,FBXO9,SRSF5,FXR2,ARSK,KDM3A,TXNDC11,PSMA4,RASA1,MAGED2,MTFMT,PRDX3,NFKBIA,AURKA,PLOD3,OSR1,ARSB,USF2,CBX5,RAD21 |
| 1.141e-03 | -6.78 | GSE28237_EARLY_VS_LATE_GC_BCELL_DN | MSigDB lists | GSE28237_EARLY_VS_LATE_GC_BCELL_DN | 191 | 44 | 17758 | 2588 |
OTUD5,TTC39B,PPM1J,TMEM86B,PSME2,CPT2,CAST,FAM129B,ARHGEF7,PNPLA2,ARMC7,CCM2,SEPP1,AIP,REPS1,KIAA1161,CHPF,DAPK2,APOBEC3B,ATP6V0B,FLII,VASP,CDK16,SLC16A6,RPL39,RDH14,RRBP1,TAX1BP3,AK3,C10orf54,TECR,MGAT5,MPP1,DIAPH2,BCL7B,ABR,DDX23,TAPBP,RPL12,KLF12,STAT6,LIMK1,NR4A2,CCDC97 |
| 1.141e-03 | -6.78 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | 191 | 44 | 17758 | 2588 |
GALK1,ADD1,DNAJB2,MCCC1,DGKA,SELL,PSME1,GRK6,MORF4L2,MGST2,FAM101B,SPSB1,CD46,RPS6KA2,OXCT1,CDK16,IL6ST,KCNN4,LMO4,FAM102A,MPHOSPH9,NR2C1,SMC4,EPHX1,PCCB,CXXC5,MPP1,PLAUR,TNFAIP8L1,NPC2,RAB3IP,C15orf39,SESN1,DAG1,ANKRD10,CD8A,ETS2,NAT1,NAB2,NR4A3,ARRB1,SERPINI1,ACADM,FAM134B |
| 1.141e-03 | -6.78 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN | 191 | 44 | 17758 | 2588 |
MYL9,BIN1,DYNLRB1,TTC39B,FAM129B,ZCCHC24,INPP5D,MCCC1,TGFBR1,SPSB1,NFAT5,MXD1,VASP,AP1M2,CASC4,SLC44A1,TAX1BP3,RAB20,MYRIP,CASD1,MGAT5,CYP1B1,CPD,DOCK4,IFITM3,MAPKAPK3,ACVR1C,DSTN,FURIN,SPATA13,DIAPH2,RAB3IP,CD40,GLT8D2,RHOB,NIN,AHRR,ENDOD1,CD8A,PTPRJ,LRIG1,GEM,ARSB,AHR |
| 1.142e-03 | -6.77 | MARSON_BOUND_BY_FOXP3_STIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_STIMULATED | 962 | 174 | 17758 | 2588 |
CCNI,TXN,ST13,ADD1,KIF2C,CAMK1D,SLC20A1,CYP1A1,NUP210,LRRC6,CTGF,DPYSL2,RGS3,CABP1,PSMC2,TUBG1,IRF2,TNFRSF18,SLC39A10,TIPARP,CERS2,ORAI2,CENPA,RNF11,MTRF1L,ARHGDIB,ZFAND5,IDH1,SESN1,RHEB,SGPP1,TMEM164,MAP2,CAB39,MRPS28,APBA2,NRGN,RTN3,CDK17,NCKAP1,TNFRSF19,PRRG4,ZNRF2,KCNN4,ATP5H,PPP4R1,SRP54,NPTN,PIM1,PIKFYVE,CTSD,LRIF1,TMED2,HP1BP3,FAM69A,GFPT1,DDB2,MAPKAPK3,SPA17,FHL2,KCTD20,FAM133B,GLT8D2,GLCE,NCOA3,SCARB2,FAM64A,CSF1,TMEM30A,CGREF1,P4HA3,S100A5,MAP3K5,NRBP1,SNX30,XDH,ELK4,ARHGAP11A,SLC25A24,AVPI1,TP53,DGKA,TESK2,FTH1,BLCAP,CD274,TMEM19,TMPRSS4,SYTL2,IER3,UHRF1BP1L,APLP2,KHNYN,WDR44,CDKN1B,DIXDC1,ECE1,ACSL4,SEPHS1,CPD,LGALS8,SEPT6,COQ10B,LYRM1,PTGER4,IGSF8,SLC11A2,GLO1,DNAJB14,GTF2A2,ATP10D,CMTM7,AMZ2,HSF4,FYN,PTPRJ,PPP2R5A,RBL1,ABHD12,CDK19,WFS1,STAT6,SIPA1L1,PPP1CB,CHMP4B,ANXA9,C1orf43,MAD2L1BP,CBX7,KDELC2,HSP90B1,FRMD6,CENPI,SLC41A1,DAP,ERI2,FLOT1,PDIA3,ETS1,NFAT5,AKIRIN1,KIF5B,SLC25A45,MDM1,FAM160A2,CTSC,TMEM62,FAM63A,SLC35B4,SGK1,HSPA13,CNOT6L,CITED2,FAM134C,S100A6,CAMK2G,WBP5,FAH,P2RX4,SUN2,SYPL1,TGIF1,ZWINT,RHOA,MLEC,DENND1B,DBR1,FBXO9,POLD3,BCAR1,BCL10,CNOT2,SLC25A40,NDFIP1 |
| 1.149e-03 | -6.77 | V$ICSBP_Q6 | MSigDB lists | V$ICSBP_Q6 | 235 | 52 | 17758 | 2588 |
ELK4,GSDMD,CCDC109B,SORBS1,PARP12,CPEB4,HOXB7,KLHL13,TAP1,DGKA,ERBB2,OSR2,TNFRSF19,IL22RA1,SCML1,DTX3L,CDKN2C,CXCL16,IRAK1,FRY,DNAH6,ATP5H,MGAT4A,ZIC5,RRBP1,FUT8,DUSP10,TWIST1,ARMCX6,DDB2,TGIF1,CASK,CITED4,RIPK2,LGALS8,USP18,SYNE2,SLC11A2,IFIT3,ITPR3,NDRG3,TAPBP,BANK1,CASP7,CCDC6,TBX1,STAT6,ITPR1,MAP3K11,IFIH1,CBX4,ZBTB33 |
| 1.149e-03 | -6.77 | OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | MSigDB lists | OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | 117 | 30 | 17758 | 2588 |
PRSS8,PSMB4,PLSCR1,GLO1,HMGN3,MEST,OAT,SLC25A5,RHEB,ARF4,CKAP5,GNAS,BTG3,SPP1,EFR3A,NMI,SPINT2,ATP13A3,RANBP1,CAPG,CD9,PRKCI,CKS1B,MDH1,IFIT1,ATP1B3,SRSF9,MELK,RAD21,CKS2 |
| 1.152e-03 | -6.77 | breast-hyperplasia-atypical_ductal_hyperplasia | COSMIC cancer mutations | breast-hyperplasia-atypical_ductal_hyperplasia | 24 | 10 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 1.152e-03 | -6.77 | atypical_ductal_hyperplasia | COSMIC cancer mutations | atypical_ductal_hyperplasia | 24 | 10 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 1.153e-03 | -6.77 | acinic_cell_carcinoma | COSMIC cancer mutations | acinic_cell_carcinoma | 32 | 12 | 17775 | 2585 |
CTNNB1,PTEN,PIK3CA,TP53,ERBB2,KIAA1109,SAMD8,LRRC1,APBA1,EGFR,CCDC74A,SLC25A36 |
| 1.153e-03 | -6.77 | ovary-low_malignant_potential_(borderline)_tumour-serous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-serous | 32 | 12 | 17775 | 2585 |
RB1,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 1.154e-03 | -6.76 | ST_INTEGRIN_SIGNALING_PATHWAY | MSigDB lists | ST_INTEGRIN_SIGNALING_PATHWAY | 82 | 23 | 17758 | 2588 |
AKT1,ARHGEF7,ITGA6,MRAS,ILK,BCAR1,MAPK8IP1,ARHGAP35,PAK6,ZYX,PLCG1,FYN,VASP,ITGA3,PTEN,P4HB,ITGA7,PLCG2,PAK2,MYLK,PIK3CA,MAP3K11,TLN2 |
| 1.154e-03 | -6.76 | MITOSIS | MSigDB lists | MITOSIS | 82 | 23 | 17758 | 2588 |
PLK1,ZWINT,CIT,NDC80,NUSAP1,KIF2C,RAD17,PKMYT1,ANLN,CDC25C,KIF11,NPM2,CCNA2,CDCA5,NEK2,AURKA,KIF22,BUB1,KNTC1,CENPE,UBE2C,ESPL1,SMC4 |
| 1.154e-03 | -6.76 | GUO_HEX_TARGETS_UP | MSigDB lists | GUO_HEX_TARGETS_UP | 82 | 23 | 17758 | 2588 |
CD99,FZD4,IQGAP1,EPHA4,CALM1,CALM3,DIAPH2,RAB6A,STIL,CMTM6,ABCD4,CALM2,PGF,SLC6A6,IGF1R,PTEN,IMPAD1,WWTR1,KLF9,LIFR,KLF7,FGD1,RRAGD |
| 1.164e-03 | -6.76 | TTCYRGAA_UNKNOWN | MSigDB lists | TTCYRGAA_UNKNOWN | 314 | 66 | 17758 | 2588 |
NCKAP5,ACVR1,ST13,SOD2,CD274,MORF4L2,CDIPT,SEPT4,FAM101B,PDGFB,MAP1LC3B,CYP39A1,PER2,APLP2,GRHL1,TSPAN6,PASK,BCL6,MYT1,SCN3A,TBC1D10B,LGALS8,LYRM1,SLC35C1,IDH1,PNKD,MAP3K6,VCP,RAB2B,CXXC4,AIFM3,HSPB1,NRGN,RECQL,PLSCR4,CDH22,DNAJB2,SLC25A27,TXNDC9,CNTNAP2,POMGNT1,PKN1,ADRBK1,ARSG,CYR61,RIMS2,PGM1,TGIF1,STAT4,PIK3R1,SPA17,VWA1,LRRC1,GOLT1A,UNC45B,MUM1L1,TMEM50B,PROM1,CCDC6,TMC5,E2F1,GRIN2D,SEMA3A,RPS6KA3,ACOT7,JARID2 |
| 1.165e-03 | -6.76 | lung-carcinoma-pleomorphic_carcinoma | COSMIC cancer mutations | lung-carcinoma-pleomorphic_carcinoma | 10 | 6 | 17775 | 2585 |
KIF5B,ERBB2,CTNNB1,EGFR,PIK3CA,TP53 |
| 1.167e-03 | -6.75 | ACEVEDO_LIVER_CANCER_UP | MSigDB lists | ACEVEDO_LIVER_CANCER_UP | 913 | 166 | 17758 | 2588 |
SUN1,TRIM2,FAM160B1,TAP1,UBE2Q1,F11R,ITPR2,MORF4L2,CENPN,CARD10,PLS3,TYMP,BTG3,UBE2T,METTL7A,IMPAD1,PPP1R16A,PAPSS1,RDH14,RGS5,MARCH2,TMEM37,RNF26,TFG,MYRIP,CPE,KIFC2,LAP3,ACBD3,C12orf65,MCFD2,TCN2,RHEB,LCP1,IRX3,LRRC42,PLCG1,TRAM2,HLF,RBM47,WDR11,WIPI1,P4HA2,TDRD7,IARS2,PRKCDBP,ADIPOR1,MRPS28,KPNA2,HSPB1,GRN,MRPL44,SCOC,HLA-E,HLA-F,SLC1A3,HERC6,RAC2,UBE2Q2,PRICKLE4,OCRL,SRP54,RFX5,HLA-C,FAM84B,STT3B,MYLIP,KCTD3,PIGC,PRODH,MRPS33,TESK1,LPGAT1,SPA17,BTN3A2,PRRC1,PCTP,AMDHD1,DCP2,SERTAD2,UAP1,TIMM8A,UTP14C,FAM83D,AURKA,SERPINB1,TMEM14A,DYNLRB1,IQGAP1,PKP2,CD46,CCNA2,DOK4,XYLT2,ZDHHC23,RPN2,APIP,RNASEH2A,MINPP1,LRP11,PDIA6,TMEM9,SEMA3B,CKS2,FRS3,SEPHS1,UPF3A,ERLEC1,SLC39A8,CDC20,KIF1C,NUSAP1,IRS2,PPP2R5A,SHROOM3,SLC9A6,PEX2,CANT1,PRKAR1A,SORT1,JKAMP,SH3D19,BLVRB,ARMC7,PSMD10,INTS8,NUCB2,NTAN1,ETS1,RBP7,TIPRL,XPR1,VPS26A,ZNF212,SCML1,IRAK1,KCNK5,GPC3,CD9,PRC1,ADAM15,CKS1B,KANK2,TAGLN2,CNPY3,OSGIN1,PDGFC,HES1,CASK,ASPM,TCFL5,DUSP23,GGH,BLVRA,RAB3IP,C4orf27,KLHL2,HLA-B,SWAP70,ABCB1,CSTF2,GLB1,ITGAV,CYBRD1,ZBTB33,JARID2 |
| 1.168e-03 | -6.75 | ATPASE_ACTIVITY | MSigDB lists | ATPASE_ACTIVITY | 112 | 29 | 17758 | 2588 |
RECQL,PEX6,RALBP1,SMARCAL1,ABCG2,VPS4B,DHX8,KIF20B,PIF1,ATP1B1,VCP,PICK1,ABCD4,DDX23,TOP2A,TAPBP,ATP1A1,ATP7B,PPP2R4,ABCA2,MSH2,ATP8B1,ATP1B3,ATP6V1C1,PSMC1,MSH6,ATP2B1,ABCC1,ABCG1 |
| 1.170e-03 | -6.75 | GSE2706_2H_VS_8H_LPS_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_LPS_STIM_DC_DN | 175 | 41 | 17758 | 2588 |
LRRFIP2,IL15RA,TRIP10,TRIM5,HAPLN3,PSME2,HLA-F,TAP1,PPFIBP2,UBE2Z,SAMD9,DUSP5,NFAT5,TMCC3,DTX3L,ITGB8,ZNF230,NTN1,ETV7,SCYL3,APOBEC3G,PCGF5,PLSCR1,KIAA0040,NUB1,BLVRA,DUSP4,OPTN,PI4K2B,CASP7,SERPINA1,TRIM69,PVRL2,ZNF367,C1orf21,NMI,NLRC5,JAK3,APOL2,WDR63,TMEM131 |
| 1.171e-03 | -6.75 | NOJIMA_SFRP2_TARGETS_DN | MSigDB lists | NOJIMA_SFRP2_TARGETS_DN | 24 | 10 | 17758 | 2588 |
GAS2L1,GRN,MX1,CCND1,STAT1,TACSTD2,BCL2L1,EGFR,SGPL1,RAD21 |
| 1.173e-03 | -6.75 | Wnt Signaling Pathway NetPath | WikiPathways | WP363 | 115 | 32 | 4455 | 729 |
RUNX2,SOX9,CUL1,FZD6,CTNNBIP1,CCND1,CTNNB1,CDH1,TFAP2A,DLG1,BRD7,TAX1BP3,MAP3K7,WNT3A,CAMK2G,DVL2,RHOA,AKT1,FZD4,BCL9,FHL2,CDC25C,CDK1,FZD7,MAPK8IP1,MAP1B,CXXC4,ANKRD6,NKD1,ARRB1,FZD5,CTBP1 |
| 1.175e-03 | -6.75 | FARDIN_HYPOXIA_11 | MSigDB lists | FARDIN_HYPOXIA_11 | 32 | 12 | 17758 | 2588 |
BTG1,PGM1,IGF1R,TNIP1,ZNF395,P4HA2,NDRG1,BNIP3L,AK4,EGLN3,KDM3A,EGLN1 |
| 1.175e-03 | -6.75 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS | 32 | 12 | 17758 | 2588 |
SOD1,PRSS23,ITGB8,NDRG1,SOX9,BNIP3L,FLOT1,CTNND1,TP53I11,SGCB,SYK,EFNB1 |
| 1.175e-03 | -6.75 | PID_NETRIN_PATHWAY | MSigDB lists | PID_NETRIN_PATHWAY | 32 | 12 | 17758 | 2588 |
PLCG1,FYN,RHOA,PIK3R1,DAPK1,PIK3CA,PITPNA,YES1,UNC5B,NTN1,BCAR1,MAP1B |
| 1.178e-03 | -6.74 | mandible | COSMIC cancer mutations | mandible | 28 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,SMO,PIK3CA,TP53,ERBB2,IDH1,JAK3,EGFR |
| 1.178e-03 | -6.74 | MAP_KINASE_KINASE_KINASE_ACTIVITY | MSigDB lists | MAP_KINASE_KINASE_KINASE_ACTIVITY | 10 | 6 | 17758 | 2588 |
MAP3K3,MAP3K7,MAP3K5,MAP3K6,MAP3K11,MAP3K9 |
| 1.178e-03 | -6.74 | TURJANSKI_MAPK14_TARGETS | MSigDB lists | TURJANSKI_MAPK14_TARGETS | 10 | 6 | 17758 | 2588 |
ELK4,TP73,ELK1,FOS,STAT4,TP53 |
| 1.178e-03 | -6.74 | LYSOSOMAL_MEMBRANE | MSigDB lists | LYSOSOMAL_MEMBRANE | 10 | 6 | 17758 | 2588 |
LAMP2,SLC17A5,CTNS,CD63,LAMP3,ABCA2 |
| 1.179e-03 | -6.74 | LEIN_NEURON_MARKERS | MSigDB lists | LEIN_NEURON_MARKERS | 63 | 19 | 17758 | 2588 |
SMARCA2,KIFC2,REPS2,SYP,RAB6A,CYFIP2,PRKACA,ALCAM,BEX2,GABARAPL1,TRANK1,MADD,CPLX1,LRP11,PACSIN1,NDFIP1,MYO5A,FBXW5,TUBA4A |
| 1.185e-03 | -6.74 | B Cell Receptor Signaling Pathway | WikiPathways | WP23 | 158 | 41 | 4455 | 729 |
INPP5D,RPS6KA1,RASGRP3,MAPK4,TEC,ITPR2,RB1,CCNA2,CTNNB1,PIK3AP1,CD22,PLCG2,BCL6,BAX,MAP3K7,SYK,RHOA,PTPN18,AKT1,CASP9,PIK3R1,PIP4K2C,CR2,PRKCQ,DUSP4,ELK1,CBL,BCAR1,RASA1,BCL10,MAPKAPK2,PLCG1,CASP7,BANK1,FYN,ITPR1,NFKBIA,STAT1,ARPC2,CD81,GAB1 |
| 1.186e-03 | -6.74 | BCL10 (B-cell CLL/lymphoma 10) | protein interactions | 8915 | 54 | 18 | 16036 | 2547 |
IL15RA,AKT1,RIPK2,TRAF2,CASP9,XIAP,PRKCQ,CARD19,SLC20A1,CARD10,PRRG4,BCL10,SOCS3,IRAK1,PELI2,NFKBIA,MAP3K7,CAMK2G |
| 1.186e-03 | -6.74 | Platelet activation | KEGG pathways | hsa04611 | 130 | 34 | 6908 | 1076 |
PLA2G4A,PPP1R12A,ITPR2,PRKACA,ITGA2B,VASP,STIM1,PLCG2,PIK3CA,PRKG1,PRKCI,MAPK11,PIK3CD,PPP1CA,TLN2,F2R,PLCB2,SYK,RASGRP1,RHOA,AKT1,PIK3R1,ITPR3,MYL12A,RASGRP2,ARHGAP35,GNAS,FYN,MYLK,ITPR1,PPP1CB,MAPK13,MYL12B,MAPK12 |
| 1.190e-03 | -6.73 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP | 102 | 27 | 17758 | 2588 |
ENPP4,TRIM2,SERTAD4,TMX4,FAM102B,PRKAR2B,TMTC2,C3orf58,SP4,ARHGEF26,MECOM,ALDH5A1,ABHD12,METTL7A,TSPAN6,LMO4,PASK,FBXL14,ZNF704,FAM117A,SLC27A1,CNPY3,TRAF5,GLCCI1,MYLIP,CHPT1,FOXA1 |
| 1.192e-03 | -6.73 | Type I pneumocyte differentiation | biological process | GO:0060509 | 7 | 5 | 16441 | 2455 |
THRB,KLF2,LTA4H,THRA,NFIB |
| 1.192e-03 | -6.73 | peripheral nervous system myelin maintenance | biological process | GO:0032287 | 7 | 5 | 16441 | 2455 |
MPP5,SOD1,FA2H,AKT1,NDRG1 |
| 1.192e-03 | -6.73 | positive regulation of cholesterol metabolic process | biological process | GO:0090205 | 7 | 5 | 16441 | 2455 |
LDLRAP1,POR,PRKAA1,ABCG1,SEC14L2 |
| 1.192e-03 | -6.73 | dendritic spine maintenance | biological process | GO:0097062 | 7 | 5 | 16441 | 2455 |
CTTN,ITGA3,TANC1,ITPKA,PICK1 |
| 1.192e-03 | -6.73 | centrosome separation | biological process | GO:0051299 | 7 | 5 | 16441 | 2455 |
AURKA,CNTROB,NDE1,KIF11,NEK2 |
| 1.193e-03 | -6.73 | FERM_CS | interpro domains | IPR019747 | 24 | 10 | 18293 | 2672 |
EPB41L5,FARP1,FRMD4A,NF2,EZR,EPB41L4B,TLN2,EPB41L4A,FARP2,FRMD4B |
| 1.193e-03 | -6.73 | LIM_MAMMARY_LUMINAL_MATURE_DN | MSigDB lists | LIM_MAMMARY_LUMINAL_MATURE_DN | 97 | 26 | 17758 | 2588 |
SORBS1,COL6A2,FRMD4A,TFAP2C,PRICKLE1,NES,KCTD12,SLC1A3,JAG2,ETS1,MERTK,NFIB,EGFR,FAS,DAPK2,IRS2,TGFBR3,DPYSL2,CALD1,LMO4,COL6A1,TPST1,PKD2,TINAGL1,MOXD1,COL16A1 |
| 1.197e-03 | -6.73 | GSE27786_CD8_TCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_MONO_MAC_DN | 186 | 43 | 17758 | 2588 |
FARP1,ARAP3,TRAPPC10,CPEB4,HJURP,BLVRB,NDC80,ERCC6L,RNF182,MRAS,LBR,CYP26A1,VASP,GNB5,MCF2L,KIF14,SGK3,PLEKHF1,TINAGL1,P2RX4,TIMP2,KIF20A,TACC1,PARD3B,MPP1,CCDC34,KIF20B,PIF1,CYFIP2,LHFPL2,ARHGEF26,OPTN,IRS2,PI4K2B,DHRS13,UEVLD,PLA2G15,NETO2,DTX4,ARRB1,CBX5,EHD1,DMPK |
| 1.197e-03 | -6.73 | GSE17721_CTRL_VS_POLYIC_0.5H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_0.5H_BMDM_UP | 186 | 43 | 17758 | 2588 |
DYRK3,ACVR1,LRP4,FAM134A,C6orf106,EFHD2,GRK6,NUCB2,FLT3,PHLDA1,LBR,BCAP31,MAGOHB,CYP1A1,CDK16,PAPSS1,FAM20B,PHTF1,NEK2,FAM102A,CITED2,FLOT2,FAM134C,CAMK2G,KDELR1,MOB4,LAP3,MPP1,NUB1,KIF13A,NKAIN1,FAM73B,ANLN,IDH1,ARF4,C18orf8,LRRC42,PGF,JAK1,ACAD10,NAT1,APPL2,CPEB2 |
| 1.197e-03 | -6.73 | GSE27786_LSK_VS_BCELL_UP | MSigDB lists | GSE27786_LSK_VS_BCELL_UP | 186 | 43 | 17758 | 2588 |
CASP3,SLC25A24,TMTC3,CAMKK1,ASL,HDAC6,AIFM2,EXT2,MESDC2,ZDHHC21,ENTPD4,PAPSS1,ABCA2,ECI2,OAS3,IQGAP3,PLCB2,NAGA,TMBIM1,FARP2,KRT80,ENPP4,SLC5A11,SHMT1,MCTP1,CCDC34,MRPS35,CCNF,SPNS3,MUM1L1,PRIM1,AMZ2,DNAJC10,PVRL2,BHLHB9,HAGHL,MATN2,ARRB1,PRKCDBP,MLKL,ALG2,PDXK,ANXA11 |
| 1.197e-03 | -6.73 | ERB2_UP.V1_DN | MSigDB lists | ERB2_UP.V1_DN | 186 | 43 | 17758 | 2588 |
DDX58,ANXA3,COL9A3,RECQL,DEPDC1,CALB2,ERI2,SLC7A2,EGR3,HERC6,STIL,SS18,BTG3,ADD3,IGF1R,ALG13,PLK4,MSH2,ANKRD12,ATP8B1,HSPA13,IFIT1,MYBL1,TIAM1,KCTD3,RASGRP1,CYP26B1,ZNF84,LPGAT1,FHL2,PRKAR2B,DNAJB14,C18orf8,STK17A,FASTKD1,LRIG1,MATN2,RAB31,IRF7,CENPE,IFIH1,IFI6,USP16 |
| 1.197e-03 | -6.73 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | 186 | 43 | 17758 | 2588 |
KLF2,ZNF395,PARP14,LFNG,CNOT8,INPP5D,XYLT1,TGOLN2,SNN,HERC6,LBR,SCML1,ADD3,PTEN,FRYL,FCHO1,AIM1,OPN3,ADCK2,FXYD5,ATP8B1,SORL1,TSPAN13,SLC39A10,RCAN3,NFKB2,GM2A,ARAP2,MBP,USP31,FIGNL1,NUB1,MBNL3,GYLTL1B,CR2,RASGRP2,SERTAD2,PLEKHG1,RAB11FIP1,RPL22,ST3GAL1,ARNT,RPS6KA3 |
| 1.200e-03 | -6.73 | Cyclin_N | interpro domains | IPR006671 | 32 | 12 | 18293 | 2672 |
CCNE2,CCNC,CCNI,CCND1,CCNA2,CCNB3,CCNO,CCNJL,CCNL1,CCNB1,CCNF,CCNB2 |
| 1.200e-03 | -6.73 | STANELLE_E2F1_TARGETS | MSigDB lists | STANELLE_E2F1_TARGETS | 28 | 11 | 17758 | 2588 |
CCND1,TP73,CCNE2,HSP90B1,ENO2,CD9,CCNO,AURKA,MAP3K5,ARHGAP4,TNFSF9 |
| 1.200e-03 | -6.73 | HWANG_PROSTATE_CANCER_MARKERS | MSigDB lists | HWANG_PROSTATE_CANCER_MARKERS | 28 | 11 | 17758 | 2588 |
CALR,TXN,FBLN5,LGALS3,CTNNB1,PTEN,NDRG1,EZR,PIM1,ILK,WNT3A |
| 1.200e-03 | -6.73 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_UP | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_UP | 28 | 11 | 17758 | 2588 |
ENPP4,DDB2,CA2,FRY,PAPD7,NR4A3,ARFGEF1,BAX,RAB20,MTMR11,CENPN |
| 1.200e-03 | -6.73 | V$NFY_01 | MSigDB lists | V$NFY_01 | 241 | 53 | 17758 | 2588 |
GRHL2,CIT,SLC25A13,ETV5,SLC25A27,PDIA3,DNAJB11,KIF23,RACGAP1,NANS,SEPT4,BAHD1,SLC20A1,CYP39A1,SLC25A35,M6PR,CDH1,SHC3,RGS3,GPC3,FUT8,PASK,NEK2,RPN2,TSPAN13,GLB1L2,SELK,KLF9,NCAM1,DLG3,TSPAN33,CKS2,PLK1,UFD1L,HES1,MLEC,ADCK3,COQ10B,DSTN,KBTBD8,LDB2,KDM3A,CDK1,RHOB,VCP,FA2H,ACYP1,PRCP,PRDM5,AGFG2,KLF11,HOXB13,JARID2 |
| 1.210e-03 | -6.72 | anaplastic_large_cell_lymphoma | COSMIC cancer mutations | anaplastic_large_cell_lymphoma | 45 | 15 | 17775 | 2585 |
RB1,RHOA,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,TFG,IDH1,FLT3,JAK3,EGFR |
| 1.211e-03 | -6.72 | microtubule motor activity | molecular function | GO:0003777 | 76 | 22 | 16491 | 2452 |
DYNLRB1,KIF3C,KIFC2,KIF20A,KLC2,KIF23,KIF1C,KIF20B,KIF13A,KIF2C,KIF26A,KIF11,DNAH3,APPBP2,KIF5B,DNAH6,KIF13B,KIF14,KLC3,KIF22,CENPE,KIF12 |
| 1.213e-03 | -6.71 | cell periphery | cellular component | GO:0071944 | 4907 | 785 | 17570 | 2579 |
DOC2A,ADD1,GRIK2,SLC25A13,PNPLA2,RET,MCOLN3,CACNA2D2,NRG2,TGOLN2,LYNX1,MORF4L2,SYTL4,SNX9,GRM5,LYPD5,CALM2,ZYX,RGS12,TGFBR3,MUC4,CABP1,PPP1R16A,SLC46A1,ATP13A3,FUT1,DNM2,CLDN4,PPP1CA,PIK3CD,WBP4,TIAM1,IL10RB,CPE,DSTN,PRKAR2B,F12,ARF4,LCP1,ABR,SLC44A3,ENPP1,PLCG1,GRID2IP,ATP7B,NOD2,RELL1,ARF6,HSPB1,SCN5A,ITGA6,RAB23,GPSM2,ZNRF3,FAM21C,MERTK,TTYH3,RAC2,FRY,CD22,FLRT3,PCYOX1,FAM84B,PANX2,CNGA1,NCAM1,ULBP2,DGKG,MYLIP,PAQR7,CALCRL,PLS1,ILK,GNA11,RHOB,PTPRF,IL1R1,SLC4A4,ETS2,SEMA4D,RAET1L,OSMR,DYSF,OSCP1,STK39,MAL2,DRP2,ARPC2,TRPC3,TMEM173,RUSC1,DMPK,MTM1,GRHL2,CD82,ETNK1,RGS20,PKP2,IL13RA1,MGST2,MVB12B,PRKACA,APC2,TNFSF9,REPS1,KTN1,MUC16,SCNN1A,CDH1,ENPP5,TAX1BP3,RTKN2,LRP11,ARL4D,DLG3,RAB27B,SCN3A,ENPP4,COL6A2,FZD4,SEPT6,PLEKHO1,SYNE2,CYS1,SYP,RAB38,XRCC6BP1,TANC1,GABARAPL1,IRS2,ALDH3B1,SHROOM3,CORO1C,SLC9A6,AXL,SIPA1L1,TRABD2A,PRIMA1,RGS14,TTC8,TCAF1,FARP1,HSP90B1,MPZL1,BACE1,TRAF2,SDC4,FLOT1,BTN3A1,CTSZ,ANO9,PKN1,PLPPR4,NUCB2,KCNC4,TSPAN17,SRPX2,ICAM1,NEO1,CAPN2,DIRAS3,CXCL16,ANK1,PDCD10,ADD3,ITGB8,IGSF9,IRAK1,SLC27A6,ANKS1B,KCNK5,GPC3,CALD1,MCF2L,ADAM15,TMBIM6,WWP1,IGFBP2,SGCB,ITM2C,TPCN1,S100A6,HCN3,AMOTL2,PVRL4,PLSCR1,CTNNAL1,FMN1,RAPGEF2,PIK3R1,GRIN1,EMP3,SNTB1,TXK,CNTNAP1,LDLRAP1,PROM1,RAB11FIP2,ACVRL1,SYT7,ITGAV,FHL1,CD81,CYBRD1,ILDR1,TNK1,BCAM,AGRN,EPHA4,F11R,ITPR2,CDIPT,HDAC6,PDGFB,SDC1,SPTB,SLC9A3R2,SUSD2,CPNE2,INPP5E,TM9SF2,CTNNB1,NPNT,SHC3,P4HB,IL6ST,SLC44A1,ABCA2,TNFRSF18,RGS5,NTN4,TLN2,ANO4,SMAGP,CD55,KCNIP3,MARK1,CELSR2,HN1L,CR2,EZR,NKAIN1,ESYT1,ANLN,CLCN2,PLCH1,HS6ST1,MFAP3L,KCNMB4,PRKCDBP,ARRDC1,CTNND1,PIK3C2B,PIEZO1,TC2N,PRSS8,USH1C,BMF,LGALS3,FXYD3,RASA2,HLA-F,SLC22A31,RACGAP1,NCKAP1,CNTNAP2,DHRS3,IL18R1,ANO1,CORO1B,B4GALNT1,BMP2,VASP,IGF1R,FRAS1,ICAM5,PAK2,FCHO1,TBCD,EXOC8,SELK,PIM1,TMEM8A,WNT3A,MPHOSPH9,CKAP4,ABCC1,PCDH1,RGMB,SPATA13,SCRIB,PRX,NMT2,CDK5R1,RASGRP2,EPN3,PVRL2,COL13A1,PHLPP2,ITGA7,MFSD2A,CSF1,SLC2A6,PLD1,ATP1B3,CDAN1,IFI6,NIPA1,KCNAB3,NF2,DGKA,P2RX7,ERBB2,RASGRP3,SLC7A2,PRR7,EMP2,BCAP31,SYTL2,SDF4,CDK14,EFR3A,PLCG2,SRR,CDH3,NOTCH3,OAS3,SCN2A,GM2A,DVL2,SULF2,CLCN3,MBP,EVA1A,AKT1,PTGER4,DAG1,ATP13A2,PTGS2,DUOX1,RTN4RL1,PTPRJ,ATP1A1,IDE,ABHD12,MMP17,PTK7,CHMP4B,EFNA5,SYT13,BIN1,PACSIN2,CDH22,ADGRG1,CD63,TAB3,CTSB,BLVRB,GNAL,ERCC6L,GABRG2,SELL,JAG2,AIP,PARM1,IL22RA1,FZD6,SLC9A2,NRP2,SIRPA,M6PR,ZDHHC21,CD109,CDK16,ALPP,MAGEE1,SGK1,IL17RA,TSPAN13,KLF9,SYK,CAMK2G,ATP2B1,TLE6,IGDCC4,HMMR,P2RX4,DLGAP1,RHOA,IFITM3,CRB3,PLAUR,CRIP2,LITAF,CAPNS1,BCAR1,BBS2,RNPEP,DGKE,BCL10,USP6,CD83,TMEM50B,FAT4,ZMYND19,NETO2,PKD2,ICOSLG,NDFIP1,ZBTB33,ARHGEF4,DIS3L,LAMP1,ACVR1,SSH1,LGR4,HSPG2,VANGL1,FAM129B,ATP8A1,PLXNA1,PJA2,SLC20A1,PICK1,NCS1,CTGF,STIM1,RGS3,OSBPL3,IL31RA,STEAP2,KCNS3,PIK3CA,TACSTD2,HYLS1,PACSIN1,XKR8,METAP2,LAMP2,SGCE,ACVR1C,SNTB2,MGAM,SLC17A5,SLC25A5,RAB2B,SLC25A4,NKD1,FAM110C,TMEM8B,SPRY4,UNC5B,SLC31A2,F2RL1,TRAF5,LZTS1,DDX58,SEMA6B,INPPL1,HLA-E,DGKQ,PRKAA1,SLC1A3,NOTCH2,APBA1,TSPAN7,MESDC2,CALR,ITGA3,RALGPS2,SNX18,LYPD3,ZNRF2,PIK3AP1,VASN,SLC16A6,PRKG1,OPN3,DAPK1,SORL1,CD70,TNFRSF12A,CACNA1D,SYTL3,TSPAN33,GPR161,RIMS2,TRAK2,EPB41L5,FADS2,KCNJ12,MMD,MFI2,CEP89,MICB,CALM1,AMER1,ANO6,DCHS1,PTPRH,PYGL,VEZT,EPHA1,ATP8B3,PKM,ANTXR1,RASA1,STX3,FAS,DGKH,MMP15,GABRD,SLCO4A1,PLEKHH2,TJP3,ZDHHC20,SLC4A3,ARAP1,MPP2,PCDH19,EFNA1,NRBP1,EHD1,SPRED1,SLC2A4,TCTN2,TRIP10,ST14,IQGAP1,NDRG1,CERCAM,ATP2C2,KCTD12,CD274,DDR1,FLT3,GNB2,EPM2A,EPS8L2,CD46,APLP2,RALB,CNNM4,DAB2IP,PDE4D,EPHB4,OSBPL7,PHKA2,TSPAN1,FLOT2,TBC1D10B,MYO5B,SLC5A11,DMTN,PANK1,UTRN,CLSTN1,PRKCQ,SLC11A2,ATP1B1,CBL,ITPR3,ALCAM,ATP10D,FZD7,EPHA10,FYN,JAK1,STK26,TSPAN18,SLC27A1,KLF5,NRG1,RAB29,MLKL,HS3ST3B1,COBL,PRKAR1A,PLSCR4,ANKRD13D,SLC16A14,ATP9A,SLC41A1,EPS8,ARL4C,PLD2,SLC35G2,EFNB1,ADGRB2,HLA-A,RND1,SNTA1,GNB5,PTEN,PRC1,CD9,ATP8B1,SLC44A2,ERBB3,MAP3K7,SLC16A5,SPRY2,MSH6,PDGFC,RASGRF1,CASK,ARHGEF28,ERMAP,MPP1,VAMP3,FURIN,UBAC1,YES1,AIF1L,CPTP,RGS9,CTNS,FGFR2,ABCB1,RYK,GRIN2D,GPER1,FZD5,DEF6,MELK,OCLN,ESYT2,RGMA,CASP3,MPP5,CACNB4,DNER,SLC8B1,TMC1,SH3KBP1,HTR1D,ABCD4,EPCAM,NKAIN3,RAB15,CDKL5,TSPAN6,DLG1,TRPC1,RAB20,RP2,CTTN,SLC39A10,PTPRE,MYRIP,IL1RAP,RASGRP1,TDP1,SOD1,ITCH,ROR1,STK17B,EDNRA,GPRC5B,KCNK1,MADD,ADIPOR1,APBA2,CPPED1,CAPN1,CD99,LASP1,ARAP3,SERPINE2,BVES,ABCG2,CALM3,TEC,PHLPP1,QSOX2,CA2,NOXA1,OCRL,KCNN4,COL6A1,PRKCI,FXYD5,NPTN,C10orf54,HLA-C,KNTC1,SLC12A2,GAD1,CCDC88A,PODXL2,SPA17,BTN3A2,NUBP1,STEAP1,EGFR,GNAS,XKRX,TSC1,SLC6A6,INSR,UAP1,PLPP3,TMEM30A,CDCA5,NFKBIA,RHOBTB2,SHROOM2,JAK3,DRD1,PROM2,SORBS1,IL15,SLC2A8,HDAC11,ABCG4,IL27RA,MRAS,MICALL2,LRRC45,FRYL,KIF14,SMO,STEAP3,ECE1,PDIA6,F2R,HSPA2,UPF3A,FRS3,SEPHS1,CHP1,SUSD3,GCA,BAG4,KREMEN2,PTPRU,SLC39A8,IGSF8,ERBB2IP,CD40,JADE1,BFSP1,SECTM1,SPTBN5,PLXND1,LIFR,ABCA1,ANXA3,FBLIM1,SORT1,ENO2,TSPAN15,SH3D19,FRMD6,ARHGEF7,LRP4,TGFBR1,XPR1,ITGA2B,IL17RB,ADORA1,ADRBK1,LLGL2,KIAA0319,ARVCF,IQGAP3,SLC35A1,SYPL1,ADAM17,RAB3B,LEPR,MAP1B,HLA-B,CD8A,SWAP70,TRIM69,PRCP,CTSV,RAP2C,ARRB1,GEM,ATP6V1C1,L1CAM,CD33,ABCG1 |
| 1.213e-03 | -6.71 | SENESE_HDAC1_TARGETS_DN | MSigDB lists | SENESE_HDAC1_TARGETS_DN | 230 | 51 | 17758 | 2588 |
NUDT6,FOXO6,BCAM,MRC2,TRIM2,RUNX2,ALDH6A1,ZNF395,AASS,DNAJB2,FLYWCH2,SDC1,FBLN1,ARHGEF40,EPS8L2,CD46,NOTCH3,MYBL1,F2R,CPE,EPB41L5,THRB,ORAI2,SSH3,CXXC5,CYS1,BNIP3L,UTRN,STMN3,PYGL,TNS1,FOS,CDC25C,BCAR1,COL12A1,NMT2,ARHGAP35,ALDH5A1,DHRS2,ITGA7,MYLK,FAM114A1,HDAC1,PKD2,CBX5,IFI6,COL16A1,NRBP1,L1CAM,CSRP2,KLF7 |
| 1.215e-03 | -6.71 | acute_myeloid_leukaemia | COSMIC cancer mutations | acute_myeloid_leukaemia | 10922 | 1658 | 17775 | 2585 |
IBTK,GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,TRAPPC8,BAIAP3,SNX9,FAM46C,SPSB1,CMTM6,CARD10,LTBP3,GRM5,LYPD5,CDKN2C,NPM2,MUC4,UBE2T,PAQR5,ATP13A3,DNM2,CRY2,RNF26,WBP4,TIAM1,IL10RB,CPE,TIPARP,MGAT5,DNAAF3,CCDC74A,NEK4,FBXL16,CDA,KDELR3,TFAP2C,PRKAR2B,PNKD,LCP1,ENPP1,BOLA3,PLCG1,MPRIP,ATP7B,CELF5,FAM114A1,TRAF3IP1,TMOD2,RNASEL,ITPKA,STARD13,ZNF720,SCN5A,ITGA6,RAB23,ARHGEF35,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,MARCH8,FLII,RAC2,FRY,PAIP2B,MEGF8,FLRT3,RANBP1,FBXL14,PCYOX1,MAP3K9,SLAIN2,CADPS2,USP38,ALPK1,CNGA1,ZMYM1,MOXD1,MYLIP,ULBP2,DGKG,KANK3,NUP85,MCCC2,HPS3,SHARPIN,KIF20B,GOLT1A,DPYSL4,SFXN5,GNA11,PLIN5,IL1R1,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,DGAT2,OSCP1,CBX5,TMEM173,ADAMTS16,DOCK9,WDR63,LFNG,PTTG1,RHBDL3,GRK6,MGST2,MOCS1,KIAA1147,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,ZNF365,MYT1,SNX10,TMCC2,MX1,SNX8,COL6A2,RIPK2,APOBEC3D,PFKFB2,AGPS,PTPN9,SEPT6,DNAJB14,TANC1,ZNF618,TRIM7,EBF2,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,PNPLA6,FAM149A,ISOC1,MAPK12,CTHRC1,MZT1,HSP90B1,MPZL1,FAM189A2,GCAT,ESRP1,TRAF2,CCM2,SDC4,FLOT1,CTSZ,SLC25A43,NFAT5,FUT2,ITGB8,KNDC1,MGAT4A,TMEM62,TUBGCP6,FAM20B,RAG1,CASD1,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,NUB1,CXorf57,PGBD1,RAB3IP,CNTNAP1,RGPD5,PROM1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,SLC35B3,FAM3C,PPM1H,ITGAV,OSR1,CMPK2,PHC1,TLL2,TMEM131,CCNI,ILDR1,TNK1,BCAM,KIAA1462,EPAS1,LMCD1,PHOSPHO1,DNAJB11,TEX2,F11R,GALM,MGAT5B,ITPR2,SPTB,SLC9A3R2,FANCI,TFAP2E,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,NPNT,PSMC2,PAPSS1,SLC44A1,ABCA2,NTN4,SMAGP,PLK1,KRT80,THRB,MARK1,PTPN18,CELSR2,STAU2,NFE2L1,CR2,CCBL2,NKAIN1,EAF2,TRUB1,DZIP1L,TRIM9,TNS4,TRAM2,KLF12,ARRDC1,KLF11,KPNA2,MYL12B,TC2N,HS6ST3,RRAGD,PARP12,USH1C,HJURP,DNAJB2,FXYD3,RASA2,SORBS3,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,SELK,PIM1,FAR2,WNT3A,NTN1,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PRX,NMT2,C18orf8,COL13A1,KBTBD2,PHLPP2,NLRC5,ZDHHC7,ZDBF2,PLD1,AKIP1,SEMA3A,CDAN1,USP43,RAD21,HOXB7,CTDSPL,TMX4,TP53,RHPN2,P2RX7,BAHD1,EMP2,PRR7,STIL,SYTL2,PDGFA,TTC21B,WDR44,TACC2,PPME1,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,ZNF628,IDE,PTPRJ,ABHD12,RBL1,STK38,MAOA,EFNA5,IRF7,ARHGAP4,FAM134B,CTDSP1,BIN1,ZMAT1,CDH22,CPEB4,CTSB,GNAL,MCTP2,HAL,ERI2,HMGN3,LBR,IL22RA1,VPS26A,PARM1,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,CD109,FOXP2,ALPP,GTF2F2,FAM63A,IL17RA,TRIM21,SGK1,CPLX1,ALDH7A1,SYK,LRRC24,DUSP1,P2RX4,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,USP6,BCL10,DDX23,CNOT2,DDAH1,SMTNL2,NEIL3,NIPSNAP3A,E2F1,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,VANGL1,CUL1,PDGFRL,PSME1,NANS,VASH1,OAT,PJA2,PICK1,SLC9A7,PAK6,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,POLL,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,METAP2,SPATA18,CDYL,BNIP3L,KIF13A,LDB2,POR,RAB2B,PRIM1,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,SLC31A2,CCDC97,FGD1,SEMA6B,RECQL,MRC2,TBC1D1,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,SH3RF2,MESDC2,CALR,DOPEY2,RALGPS2,LYPD3,ZNRF2,RPL39,AIM1,MSH2,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,DLX4,KCTD3,SYTL3,TRAK2,PIGC,GFPT1,SPATA20,GCC2,PRODH,KCNJ12,KLK5,CEP89,ADCK3,DCHS1,PYGL,WHSC1,NPC2,ATP8B3,ANTXR1,NFIB,PDE11A,NT5C2,PLEKHH2,TJP3,FAAH,ZDHHC20,C1orf21,MATN2,PIAS2,FAM83D,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,KLK7,ZBTB34,PER3,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,CAPN12,CCDC110,NDRG1,CERCAM,ATP2C2,FTH1,BLCAP,BCL2L1,TMEM170B,TMEM19,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPS8L2,APOBEC3B,NOV,CCNA2,ACAP2,TRANK1,RALB,BRI3,EPHB4,PDE4D,OSBPL7,SULT2B1,FLOT2,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,CLSTN1,UTRN,KIF1C,CBL,ITPR3,ASB13,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,ACAD10,CCDC149,TSPAN18,ZNF704,SLC27A3,COBL,CBX7,MAMDC2,PRKAR1A,PLSCR4,DEPDC1,HAPLN3,CENPI,EPS8,NES,HERC5,PBX3,PLD2,FBXO6,DNAH3,HLA-A,WWP2,SLC25A36,CKAP5,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,ERBB3,CITED2,MSH6,FARP2,TGIF1,ZWINT,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,KIF11,CDK5RAP1,CRTC2,TIMP3,ACADSB,DGCR2,SEC14L4,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR62,WDR91,ESPL1,MELK,UGT8,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,COMMD5,TRIM68,ECI1,HTR1D,ADPRHL1,RAB15,SIPA1L2,CASC4,CDKL5,ARHGEF37,SIVA1,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,NLRP4,CENPA,ASXL1,ACBD3,RGAG1,ARHGDIB,MAN2A2,GPRC5B,KCNK1,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PCSK5,CD99,LASP1,PPP1R2,PPP1R12A,SERPINE2,BVES,PYROXD2,ABCG2,PM20D2,FAM81A,DUSP5,QSOX2,TYW3,B3GALNT1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,SNED1,MDFI,SNX7,TPGS2,PODXL2,PDE5A,KIAA1109,PRRC1,HEATR5A,MFSD7,RANBP9,STEAP1,INSR,TMEM30A,SPAG7,DCUN1D1,SH3BP4,RAB31,DONSON,SHROOM2,JAK3,COL16A1,AFAP1,DRD1,LMO7,CCNE2,NCKAP5,LZTFL1,PAX6,PDIA5,COL18A1,IL27RA,KCTD9,SAP130,ZNF687,CYP4F11,KIF14,REEP1,ZBTB49,EPB41L4B,ECE1,NFKB2,EBAG9,SEPHS1,SOAT1,PTPRU,MRPS35,GLO1,TMTC2,CDC25C,FANCE,PDHX,ARHGAP35,HSF4,ALDH5A1,STAT6,PTBP3,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,ARHGEF7,SHPRH,SH3D19,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,SYDE2,TMEM63A,CARD8,TAF1B,ADRBK1,LLGL2,TOX2,RRBP1,ZDHHC13,ACTA2,H2AFY,ARVCF,KANK2,CLIP2,SLC35A1,MYO5A,PGM1,DCAF6,SYBU,TTC7A,FAM73B,LEPR,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,FIBCD1,SPINT2,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,ABCG1,CD33,NGEF,ACACB,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,MMADHC,CACNA2D2,SMARCAL1,DHX8,NRG2,IL18,LGI3,SYTL4,CNTROB,CA8,BARD1,TP73,ZYX,WEE1,TGFBR3,RGS12,AP1M2,ARHGAP42,PQLC2,KIAA1107,DNAH6,CYP2S1,CABP1,SLC46A1,RDH14,ALDH1A3,FUT1,TUBG1,PIK3CD,ODF2L,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,RNF11,MTRF1L,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,WDR11,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,RELL1,PDPR,GAB1,E2F8,FAM169A,ALDH6A1,NFKBIE,TMTC3,CYP2J2,MERTK,RAVER2,GNS,DNPEP,WDFY1,FAM189A1,CD22,NEK2,STT3B,NCAM1,EPHX1,NAGPA,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SPTLC2,CYB5A,RHOB,STK17A,DHX32,PTPRF,NAAA,NCOA3,SCARB2,MTFMT,HTT,TEX30,ITPR1,DYSF,AURKA,OSMR,FBXO27,NDE1,DRP2,TRPC3,ZNF502,SERPINB1,RPS6KA3,XDH,ARHGAP11A,CCDC109B,GRHL2,PAPSS2,GALNT12,FAM131C,ACTR8,WDTC1,ETNK1,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,UHRF1BP1L,SCNN1A,RNF220,SP100,DACT1,RTKN2,TMEM9,SCN3A,RNF169,ENPP4,SSH3,PSRC1,LGALS8,FZD4,SYNE2,CDCA2,STX10,TTC12,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,TAOK2,TNRC6C,PLEKHJ1,RASSF7,PDIA3,GMCL1,ANO9,PKN1,GSTP1,ETS1,KCNC4,TIPRL,PDIA4,NEO1,CAPN2,DTX3L,CXCL16,ANK1,ADD3,SLC27A6,ANKS1B,ARSG,KCNK5,CALD1,ALG13,FDXR,ECI2,ZNF230,WWP1,NPTXR,ITM2C,TMX1,CRTAP,AMOTL2,LCA5,CTNNAL1,FMN1,RAPGEF2,EIF5A2,GRIN1,PLEKHA7,MYEOV,EMP3,BLVRA,CRISPLD2,ABLIM2,TXK,PITX2,GALNT3,KIAA0141,ATXN7L3,NR1D2,CCDC6,ARFGAP3,CENPE,SHOX2,DCBLD1,CYBRD1,MYL9,TRIM2,AGRN,FAM199X,PPM1J,EPHA4,CUL4B,SUDS3,FHDC1,MCCC1,TP53I11,CDIPT,HDAC6,CNTRL,SHC3,ELF5,RGS5,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,MCTP1,HN1L,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,FAM212B,IDH1,CLCN2,ZBTB7B,RHEB,VCP,PLEKHB1,OPTN,DPYSL3,TBC1D17,MAP2,P4HA2,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,POMT1,GLCCI1,MAFF,PRKAA2,UBASH3B,ZCCHC24,HLA-F,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,RB1,DAZAP1,VASP,IGF1R,GATA2,MDFIC,TMEM8A,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,WDR72,PCBP3,SPATA13,TCF7,EIF2AK1,IFIT3,UNC45B,G2E3,SMN1,DHDH,MAPKAPK2,PVRL2,CSF1,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,NF2,UGP2,FOXM1,XYLT1,DGKA,CCDC68,ZNF28,ERBB2,CCNL1,SLC7A2,LPIN3,CYP26A1,PER2,RAD23A,CDK14,SRPX,EFR3A,PLCG2,GYS1,MINPP1,SCN2A,FAR1,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,TCEB2,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,RTN4RL1,C19orf66,PTK7,PSMD3,ADAMTS14,ANXA9,RPL22,LTA4H,AIFM3,ZNF701,NDST3,ZC3HC1,MAN2B2,COL9A3,GOLIM4,MACC1,RUSC2,DAP,GABRG2,SELL,NKRF,SLC9A2,SIRPA,CCDC92,CEP97,SLC35B4,ABCD1,BUB1,KLF9,SLC45A3,CAMK2G,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,PPARA,TRIM35,CAPNS1,AKAP3,FXR2,BCAR1,MAPK8IP1,PRDX4,TMEM50B,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZMYND19,ZNF214,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,ACVR1,TMEM41B,ATP8A1,KLC2,TAP1,PPFIBP2,PLXNA1,SLC20A1,CENPN,NCS1,SESN3,ELMO2,ZFP36,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,GALNT7,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ULK2,ARHGEF26,SGPP1,AHRR,SFXN1,FAM177A1,AREG,PLK2,PTER,TBX1,GNPTAB,NKD1,DHTKD1,TANC2,UNC5B,RTN3,LZTS1,DLAT,DDX58,MRPL44,INPPL1,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,NOTCH2,SLC1A3,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,OPN3,CTPS1,SORL1,CD70,PIKFYVE,RIMS2,TSPAN33,EEF1D,FAM69A,IGSF3,DNAI1,EPB41L5,PMPCB,QSOX1,B3GNT7,MFI2,KIAA1841,MMD,ZNF84,TBC1D8B,B9D2,AMER1,PTPRH,PIP4K2C,VEZT,PKM,KDM3A,FBXO10,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,NAB2,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,EFNA1,MAP3K5,NRBP1,PKD1L2,IRF1,ELK4,FRMPD3,PLA2G4A,ARMCX3,TRIP10,NLRX1,SUZ12,CAST,IQGAP1,RPS6KA1,RNF182,AIFM2,MNS1,TMPRSS4,SLC25A35,ZNF75D,FAM46A,IFIT1,LGMN,PHKA2,NR2C1,TMBIM1,GPX4,TBC1D10B,MYO5B,SLC5A11,CDKN2AIP,SEC23A,TMEM43,CAPN6,TEP1,COX11,PRKCQ,SP4,PRDM11,CMTM7,NIN,OSBPL2,EPHA10,FYN,JAK1,KIAA1804,STAT1,NRG1,MLKL,ZC3H12B,B4GALT3,NR3C2,ATMIN,DENND5B,MRPS9,WASF3,ARHGEF3,SLC16A14,ATP9A,ARL4C,CCNJL,GPR180,APOBEC3H,PNPLA5,SIX4,TMCC3,FAM111A,PHF7,PTEN,MGAT1,CENPJ,PRC1,ATP8B1,SLC44A2,TAGLN2,CNOT6L,GFI1,SPRY2,NCOA2,OSGIN1,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,ERMAP,PARP4,C1GALT1C1,LRRC1,GPLD1,RGS9,NUCB1,MAMDC4,RCBTB2,CSTF2,CCDC69,SERPINB5,SLC25A38,ARSB,NCAPG2,JARID2,ESYT2,EXPH5,LTBP1,CASP3,ST13,CPT2,CAMKK1,UBE2Z,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,LRRC6,GRHL1,DPYSL2,PHTF1,DLG1,CAPG,POF1B,ANKRD12,SUN3,RP2,ARNT2,MYH14,TECR,PTPRE,RASGRP1,OLFML2A,TDP1,ATL1,SYNE3,RNF165,ROR1,MRPS18A,PTGFRN,MRPS36,ADRBK2,STK17B,TCN2,SEC14L2,EDNRA,CXXC4,LRRC42,NEIL1,FASTKD1,IARS2,TRIM45,CCDC74B,ADIPOR1,APBA2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,ELOVL7,SAMD9,PHLPP1,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FXYD5,FNIP1,ZNF692,KNTC1,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,HP1BP3,PARD3B,OXR1,GYLTL1B,RNF113A,EGFR,GNAS,BCAR3,XKRX,TSC1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,PITPNA,SLC25A24,ZSWIM5,FAM92A1,IL15,SLC2A8,PSME2,ABCG4,TDRKH,ZMYND10,MICALL2,LRRC45,SLC25A48,SETDB2,KHNYN,FRYL,SMO,RPN2,STEAP3,PDIA6,LOXL1,FRS3,MAP3K3,GCA,ZNF525,KREMEN2,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,BFSP1,CANT1,VSIG10,PLXND1,AKNA,SGOL1,REEP4,PPP2R2D,LIFR,CBX4,CCDC24,ANXA3,CDS2,SORT1,JKAMP,POC1B,LRP4,FAM134A,MIER3,NOTUM,FAM167A,SAC3D1,IL17RB,IRF2BPL,SNX13,MDM1,MLPH,KIAA0319,BRD7,TRIM3,CKS1B,HSPA13,IQGAP3,SYPL1,SUN2,DEPDC4,GCLC,PHLDB3,ASPM,OGDHL,LRRC66,POLD3,SPAG1,MPV17L2,MAP1B,KLHL2,HLA-B,C2orf70,PRCP,UBE2D2,OTUB2,GLB1,ATP6V1C1,GEM |
| 1.215e-03 | -6.71 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | 10922 | 1658 | 17775 | 2585 |
IBTK,GRIK2,AK7,SLC25A13,PNPLA2,HEXB,RET,MCOLN3,TRAPPC8,BAIAP3,SNX9,FAM46C,SPSB1,CMTM6,CARD10,LTBP3,GRM5,LYPD5,CDKN2C,NPM2,MUC4,UBE2T,PAQR5,ATP13A3,DNM2,CRY2,RNF26,WBP4,TIAM1,IL10RB,CPE,TIPARP,MGAT5,DNAAF3,CCDC74A,NEK4,FBXL16,CDA,KDELR3,TFAP2C,PRKAR2B,PNKD,LCP1,ENPP1,BOLA3,PLCG1,MPRIP,ATP7B,CELF5,FAM114A1,TRAF3IP1,TMOD2,RNASEL,ITPKA,STARD13,ZNF720,SCN5A,ITGA6,RAB23,ARHGEF35,GPSM2,COX6C,FAM21C,TTYH3,HPCAL4,RABGGTA,MARCH8,FLII,RAC2,FRY,PAIP2B,MEGF8,FLRT3,RANBP1,FBXL14,PCYOX1,MAP3K9,SLAIN2,CADPS2,USP38,ALPK1,CNGA1,ZMYM1,MOXD1,MYLIP,ULBP2,DGKG,KANK3,NUP85,MCCC2,HPS3,SHARPIN,KIF20B,GOLT1A,DPYSL4,SFXN5,GNA11,PLIN5,IL1R1,CACHD1,SLC4A4,ETS2,RAET1L,S100A5,DGAT2,OSCP1,CBX5,TMEM173,ADAMTS16,DOCK9,WDR63,LFNG,PTTG1,RHBDL3,GRK6,MGST2,MOCS1,KIAA1147,MUC16,ST5,CDH1,SH3BP1,XYLT2,RASGEF1A,ZNF365,MYT1,SNX10,TMCC2,MX1,SNX8,COL6A2,RIPK2,APOBEC3D,PFKFB2,AGPS,PTPN9,SEPT6,DNAJB14,TANC1,ZNF618,TRIM7,EBF2,NFIX,PDLIM3,SHROOM3,CDK19,WFS1,PNPLA6,FAM149A,ISOC1,MAPK12,CTHRC1,MZT1,HSP90B1,MPZL1,FAM189A2,GCAT,ESRP1,TRAF2,CCM2,SDC4,FLOT1,CTSZ,SLC25A43,NFAT5,FUT2,ITGB8,KNDC1,MGAT4A,TMEM62,TUBGCP6,FAM20B,RAG1,CASD1,PARP9,ACBD5,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,NUB1,CXorf57,PGBD1,RAB3IP,CNTNAP1,RGPD5,PROM1,RPL12,HCP5,PLOD2,RAB11FIP2,SYT7,SLC35B3,FAM3C,PPM1H,ITGAV,OSR1,CMPK2,PHC1,TLL2,TMEM131,CCNI,ILDR1,TNK1,BCAM,KIAA1462,EPAS1,LMCD1,PHOSPHO1,DNAJB11,TEX2,F11R,GALM,MGAT5B,ITPR2,SPTB,SLC9A3R2,FANCI,TFAP2E,CPNE2,INPP5E,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,NPNT,PSMC2,PAPSS1,SLC44A1,ABCA2,NTN4,SMAGP,PLK1,KRT80,THRB,MARK1,PTPN18,CELSR2,STAU2,NFE2L1,CR2,CCBL2,NKAIN1,EAF2,TRUB1,DZIP1L,TRIM9,TNS4,TRAM2,KLF12,ARRDC1,KLF11,KPNA2,MYL12B,TC2N,HS6ST3,RRAGD,PARP12,USH1C,HJURP,DNAJB2,FXYD3,RASA2,SORBS3,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,SELK,PIM1,FAR2,WNT3A,NTN1,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,ZNF320,MGAT4B,STRADB,SCRIB,PRX,NMT2,C18orf8,COL13A1,KBTBD2,PHLPP2,NLRC5,ZDHHC7,ZDBF2,PLD1,AKIP1,SEMA3A,CDAN1,USP43,RAD21,HOXB7,CTDSPL,TMX4,TP53,RHPN2,P2RX7,BAHD1,EMP2,PRR7,STIL,SYTL2,PDGFA,TTC21B,WDR44,TACC2,PPME1,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,ZNF628,IDE,PTPRJ,ABHD12,RBL1,STK38,MAOA,EFNA5,IRF7,ARHGAP4,FAM134B,CTDSP1,BIN1,ZMAT1,CDH22,CPEB4,CTSB,GNAL,MCTP2,HAL,ERI2,HMGN3,LBR,IL22RA1,VPS26A,PARM1,NRP2,DNAJB9,FZD6,SH2D4A,M6PR,CD109,FOXP2,ALPP,GTF2F2,FAM63A,IL17RA,TRIM21,SGK1,CPLX1,ALDH7A1,SYK,LRRC24,DUSP1,P2RX4,FBLN5,RHOA,GUSB,PLAUR,PRICKLE1,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BBS2,DGKE,USP6,BCL10,DDX23,CNOT2,DDAH1,SMTNL2,NEIL3,NIPSNAP3A,E2F1,SH3BGRL2,ICOSLG,PTGES,HIPK3,ZBTB33,ARHGEF4,GOLGB1,LAMP1,LGR4,HSPG2,VANGL1,CUL1,PDGFRL,PSME1,NANS,VASH1,OAT,PJA2,PICK1,SLC9A7,PAK6,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,POLL,KCNS3,PIK3CA,IRF2,SNX16,HYLS1,MARCH2,METAP2,SPATA18,CDYL,BNIP3L,KIF13A,LDB2,POR,RAB2B,PRIM1,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,NFKBIZ,SERPINI1,WBSCR27,F2RL1,SLC31A2,CCDC97,FGD1,SEMA6B,RECQL,MRC2,TBC1D1,PRKAA1,AKAP17A,APBA1,TNFRSF19,PDXDC1,SH3RF2,MESDC2,CALR,DOPEY2,RALGPS2,LYPD3,ZNRF2,RPL39,AIM1,MSH2,PRKG1,TPST1,ADCK2,OSTF1,C8orf58,CACNA1D,DLX4,KCTD3,SYTL3,TRAK2,PIGC,GFPT1,SPATA20,GCC2,PRODH,KCNJ12,KLK5,CEP89,ADCK3,DCHS1,PYGL,WHSC1,NPC2,ATP8B3,ANTXR1,NFIB,PDE11A,NT5C2,PLEKHH2,TJP3,FAAH,ZDHHC20,C1orf21,MATN2,PIAS2,FAM83D,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,KLK7,ZBTB34,PER3,HOOK1,IFIH1,EHD1,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,CAPN12,CCDC110,NDRG1,CERCAM,ATP2C2,FTH1,BLCAP,BCL2L1,TMEM170B,TMEM19,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPS8L2,APOBEC3B,NOV,CCNA2,ACAP2,TRANK1,RALB,BRI3,EPHB4,PDE4D,OSBPL7,SULT2B1,FLOT2,DOCK4,COG2,FOXJ2,CYB5R2,DRAP1,PANK1,CLSTN1,UTRN,KIF1C,CBL,ITPR3,ASB13,ALCAM,ATP10D,ZMPSTE24,AMZ2,DDOST,ACAD10,CCDC149,TSPAN18,ZNF704,SLC27A3,COBL,CBX7,MAMDC2,PRKAR1A,PLSCR4,DEPDC1,HAPLN3,CENPI,EPS8,NES,HERC5,PBX3,PLD2,FBXO6,DNAH3,HLA-A,WWP2,SLC25A36,CKAP5,RASSF8,E2F7,TMEM87B,RNF128,FUT8,CD9,CCDC82,ERBB3,CITED2,MSH6,FARP2,TGIF1,ZWINT,ARHGEF28,LONRF3,ZC3H11A,ZKSCAN2,FBXO9,DIAPH2,C2orf69,YES1,GRTP1,KIF11,CDK5RAP1,CRTC2,TIMP3,ACADSB,DGCR2,SEC14L4,FGFR2,RIN3,TBX18,ABCB1,ERAP1,WDR62,WDR91,ESPL1,MELK,UGT8,CRYM,UBE2Q1,VARS2,PLAC1,MPP5,COMMD5,TRIM68,ECI1,HTR1D,ADPRHL1,RAB15,SIPA1L2,CASC4,CDKL5,ARHGEF37,SIVA1,ANKFN1,TRPC1,ASH2L,MYRIP,BTBD3,IL1RAP,NLRP4,CENPA,ASXL1,ACBD3,RGAG1,ARHGDIB,MAN2A2,GPRC5B,KCNK1,MADD,TDRD7,SH3GLB2,GLA,RBM43,CHPT1,CAPN1,NR2C2,PCSK5,CD99,LASP1,PPP1R2,PPP1R12A,SERPINE2,BVES,PYROXD2,ABCG2,PM20D2,FAM81A,DUSP5,QSOX2,TYW3,B3GALNT1,CES2,PFKL,COL6A1,PRKCI,LIMCH1,BRAT1,C10orf54,HLA-C,ZRANB1,GAD1,ETV7,SLC12A2,SNED1,MDFI,SNX7,TPGS2,PODXL2,PDE5A,KIAA1109,PRRC1,HEATR5A,MFSD7,RANBP9,STEAP1,INSR,TMEM30A,SPAG7,DCUN1D1,SH3BP4,RAB31,DONSON,SHROOM2,JAK3,COL16A1,AFAP1,DRD1,LMO7,CCNE2,NCKAP5,LZTFL1,PAX6,PDIA5,COL18A1,IL27RA,KCTD9,SAP130,ZNF687,CYP4F11,KIF14,REEP1,ZBTB49,EPB41L4B,ECE1,NFKB2,EBAG9,SEPHS1,SOAT1,PTPRU,MRPS35,GLO1,TMTC2,CDC25C,FANCE,PDHX,ARHGAP35,HSF4,ALDH5A1,STAT6,PTBP3,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,GLIS3,GCLM,FBLIM1,ENO2,TSPAN15,ARHGEF11,ARHGEF7,SHPRH,SH3D19,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,HMGXB4,HDAC9,SYDE2,TMEM63A,CARD8,TAF1B,ADRBK1,LLGL2,TOX2,RRBP1,ZDHHC13,ACTA2,H2AFY,ARVCF,KANK2,CLIP2,SLC35A1,MYO5A,PGM1,DCAF6,SYBU,TTC7A,FAM73B,LEPR,ENDOD1,ARHGAP24,CD8A,CASP7,SWAP70,FIBCD1,SPINT2,CSGALNACT1,DTX4,ARRB1,UACA,GRAMD1C,ZMIZ1,PLOD3,ABCG1,CD33,NGEF,ACACB,TRIM24,ADD1,IL15RA,MRPS15,AASS,TRIM5,MMADHC,CACNA2D2,SMARCAL1,DHX8,NRG2,IL18,LGI3,SYTL4,CNTROB,CA8,BARD1,TP73,ZYX,WEE1,TGFBR3,RGS12,AP1M2,ARHGAP42,PQLC2,KIAA1107,DNAH6,CYP2S1,CABP1,SLC46A1,RDH14,ALDH1A3,FUT1,TUBG1,PIK3CD,ODF2L,APOBEC3G,ERAP2,SPEF2,SMARCA2,TNIP1,RNF11,MTRF1L,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,WDR11,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,RELL1,PDPR,GAB1,E2F8,FAM169A,ALDH6A1,NFKBIE,TMTC3,CYP2J2,MERTK,RAVER2,GNS,DNPEP,WDFY1,FAM189A1,CD22,NEK2,STT3B,NCAM1,EPHX1,NAGPA,SLC37A1,KIF20A,SALL4,STAT4,MYBL2,CALCRL,PLS1,SPTLC2,CYB5A,RHOB,STK17A,DHX32,PTPRF,NAAA,NCOA3,SCARB2,MTFMT,HTT,TEX30,ITPR1,DYSF,AURKA,OSMR,FBXO27,NDE1,DRP2,TRPC3,ZNF502,SERPINB1,RPS6KA3,XDH,ARHGAP11A,CCDC109B,GRHL2,PAPSS2,GALNT12,FAM131C,ACTR8,WDTC1,ETNK1,PKP2,TESK2,IL13RA1,NUF2,PRKACA,APC2,TNFSF9,ZNF385B,CDS1,UHRF1BP1L,SCNN1A,RNF220,SP100,DACT1,RTKN2,TMEM9,SCN3A,RNF169,ENPP4,SSH3,PSRC1,LGALS8,FZD4,SYNE2,CDCA2,STX10,TTC12,SLC9A6,SIPA1L1,INPP4B,PLEKHG1,PDXK,ARNT,TTC8,FARP1,TAOK2,TNRC6C,PLEKHJ1,RASSF7,PDIA3,GMCL1,ANO9,PKN1,GSTP1,ETS1,KCNC4,TIPRL,PDIA4,NEO1,CAPN2,DTX3L,CXCL16,ANK1,ADD3,SLC27A6,ANKS1B,ARSG,KCNK5,CALD1,ALG13,FDXR,ECI2,ZNF230,WWP1,NPTXR,ITM2C,TMX1,CRTAP,AMOTL2,LCA5,CTNNAL1,FMN1,RAPGEF2,EIF5A2,GRIN1,PLEKHA7,MYEOV,EMP3,BLVRA,CRISPLD2,ABLIM2,TXK,PITX2,GALNT3,KIAA0141,ATXN7L3,NR1D2,CCDC6,ARFGAP3,CENPE,SHOX2,DCBLD1,CYBRD1,MYL9,TRIM2,AGRN,FAM199X,PPM1J,EPHA4,CUL4B,SUDS3,FHDC1,MCCC1,TP53I11,CDIPT,HDAC6,CNTRL,SHC3,ELF5,RGS5,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,CCDC38,ZNF462,MCTP1,HN1L,C12orf65,EZR,ERP44,KLK6,ESYT1,PRKRA,ANLN,FAM212B,IDH1,CLCN2,ZBTB7B,RHEB,VCP,PLEKHB1,OPTN,DPYSL3,TBC1D17,MAP2,P4HA2,RAB11FIP1,CTNND1,PIK3C2B,PIEZO1,TTC9,EPB41L4A,POMT1,GLCCI1,MAFF,PRKAA2,UBASH3B,ZCCHC24,HLA-F,ASAH1,RACGAP1,CNTNAP2,B4GALT4,DOCK11,DHRS3,IL18R1,PGAP1,SSX2IP,RB1,DAZAP1,VASP,IGF1R,GATA2,MDFIC,TMEM8A,PLCB2,ALDH3A2,ABCC1,C9orf9,CHSY3,CYP26B1,WDR72,PCBP3,SPATA13,TCF7,EIF2AK1,IFIT3,UNC45B,G2E3,SMN1,DHDH,MAPKAPK2,PVRL2,CSF1,MFSD2A,PRPS2,LTBP2,IFI6,NIPA1,NF2,UGP2,FOXM1,XYLT1,DGKA,CCDC68,ZNF28,ERBB2,CCNL1,SLC7A2,LPIN3,CYP26A1,PER2,RAD23A,CDK14,SRPX,EFR3A,PLCG2,GYS1,MINPP1,SCN2A,FAR1,DVL2,GM2A,CTH,CPD,SIRT1,TMTC1,MBP,TCEB2,FIGNL1,COQ10B,CDC20,MYL12A,DUOX1,DNAJC10,ATP1A1,RTN4RL1,C19orf66,PTK7,PSMD3,ADAMTS14,ANXA9,RPL22,LTA4H,AIFM3,ZNF701,NDST3,ZC3HC1,MAN2B2,COL9A3,GOLIM4,MACC1,RUSC2,DAP,GABRG2,SELL,NKRF,SLC9A2,SIRPA,CCDC92,CEP97,SLC35B4,ABCD1,BUB1,KLF9,SLC45A3,CAMK2G,TLE6,FAH,IGDCC4,DLGAP1,HMMR,PSMB4,CRB3,NR3C1,AMFR,PPARA,TRIM35,CAPNS1,AKAP3,FXR2,BCAR1,MAPK8IP1,PRDX4,TMEM50B,BANK1,CDKN2AIPNL,FAT4,SERPINA1,TWSG1,ZMYND19,ZNF214,NMI,TMC5,CDCA7L,NETO2,CLIP4,FAM117A,PPP2R3C,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,ACVR1,TMEM41B,ATP8A1,KLC2,TAP1,PPFIBP2,PLXNA1,SLC20A1,CENPN,NCS1,SESN3,ELMO2,ZFP36,IQCE,PRICKLE3,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,MTMR11,ORAI2,LOC81691,TMEM68,KIFC2,SNTB2,PBK,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,GALNT7,CCNF,ZFAND5,SLC25A5,TP53I3,SPNS3,ULK2,ARHGEF26,SGPP1,AHRR,SFXN1,FAM177A1,AREG,PLK2,PTER,TBX1,GNPTAB,NKD1,DHTKD1,TANC2,UNC5B,RTN3,LZTS1,DLAT,DDX58,MRPL44,INPPL1,FRMD4A,HLA-E,CALB2,DGKQ,SLC25A27,KIF23,C6orf106,NDUFA4,ISYNA1,NOTCH2,SLC1A3,BMP2K,PRRG4,ITGA3,CYR61,PIK3AP1,SNX18,SLC16A6,OPN3,CTPS1,SORL1,CD70,PIKFYVE,RIMS2,TSPAN33,EEF1D,FAM69A,IGSF3,DNAI1,EPB41L5,PMPCB,QSOX1,B3GNT7,MFI2,KIAA1841,MMD,ZNF84,TBC1D8B,B9D2,AMER1,PTPRH,PIP4K2C,VEZT,PKM,KDM3A,FBXO10,GLT8D2,STX3,RASA1,FRMD4B,FAS,DGKH,GABRD,PRKAG2,ISM1,DCK,NAB2,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,EFNA1,MAP3K5,NRBP1,PKD1L2,IRF1,ELK4,FRMPD3,PLA2G4A,ARMCX3,TRIP10,NLRX1,SUZ12,CAST,IQGAP1,RPS6KA1,RNF182,AIFM2,MNS1,TMPRSS4,SLC25A35,ZNF75D,FAM46A,IFIT1,LGMN,PHKA2,NR2C1,TMBIM1,GPX4,TBC1D10B,MYO5B,SLC5A11,CDKN2AIP,SEC23A,TMEM43,CAPN6,TEP1,COX11,PRKCQ,SP4,PRDM11,CMTM7,NIN,OSBPL2,EPHA10,FYN,JAK1,KIAA1804,STAT1,NRG1,MLKL,ZC3H12B,B4GALT3,NR3C2,ATMIN,DENND5B,MRPS9,WASF3,ARHGEF3,SLC16A14,ATP9A,ARL4C,CCNJL,GPR180,APOBEC3H,PNPLA5,SIX4,TMCC3,FAM111A,PHF7,PTEN,MGAT1,CENPJ,PRC1,ATP8B1,SLC44A2,TAGLN2,CNOT6L,GFI1,SPRY2,NCOA2,OSGIN1,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,ERMAP,PARP4,C1GALT1C1,LRRC1,GPLD1,RGS9,NUCB1,MAMDC4,RCBTB2,CSTF2,CCDC69,SERPINB5,SLC25A38,ARSB,NCAPG2,JARID2,ESYT2,EXPH5,LTBP1,CASP3,ST13,CPT2,CAMKK1,UBE2Z,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,ABCD4,ARHGEF10L,NKAIN3,LRRC6,GRHL1,DPYSL2,PHTF1,DLG1,CAPG,POF1B,ANKRD12,SUN3,RP2,ARNT2,MYH14,TECR,PTPRE,RASGRP1,OLFML2A,TDP1,ATL1,SYNE3,RNF165,ROR1,MRPS18A,PTGFRN,MRPS36,ADRBK2,STK17B,TCN2,SEC14L2,EDNRA,CXXC4,LRRC42,NEIL1,FASTKD1,IARS2,TRIM45,CCDC74B,ADIPOR1,APBA2,RAP1GAP,PPP2R5D,CPPED1,STARD3NL,GRN,LRRFIP2,PEX6,ELOVL7,SAMD9,PHLPP1,LYSMD4,ZNF432,AIM1L,CA2,LRRN2,FXYD5,FNIP1,ZNF692,KNTC1,RFX5,NCEH1,LRIF1,ALS2CL,KDELR1,HP1BP3,PARD3B,OXR1,GYLTL1B,RNF113A,EGFR,GNAS,BCAR3,XKRX,TSC1,SLC6A6,UTP14C,CGREF1,CDCA5,NFKBIA,ALPK3,RHOBTB2,PITPNA,SLC25A24,ZSWIM5,FAM92A1,IL15,SLC2A8,PSME2,ABCG4,TDRKH,ZMYND10,MICALL2,LRRC45,SLC25A48,SETDB2,KHNYN,FRYL,SMO,RPN2,STEAP3,PDIA6,LOXL1,FRS3,MAP3K3,GCA,ZNF525,KREMEN2,SLC39A8,OSTM1,IGSF8,ERBB2IP,DUSP4,DOCK5,BFSP1,CANT1,VSIG10,PLXND1,AKNA,SGOL1,REEP4,PPP2R2D,LIFR,CBX4,CCDC24,ANXA3,CDS2,SORT1,JKAMP,POC1B,LRP4,FAM134A,MIER3,NOTUM,FAM167A,SAC3D1,IL17RB,IRF2BPL,SNX13,MDM1,MLPH,KIAA0319,BRD7,TRIM3,CKS1B,HSPA13,IQGAP3,SYPL1,SUN2,DEPDC4,GCLC,PHLDB3,ASPM,OGDHL,LRRC66,POLD3,SPAG1,MPV17L2,MAP1B,KLHL2,HLA-B,C2orf70,PRCP,UBE2D2,OTUB2,GLB1,ATP6V1C1,GEM |
| 1.221e-03 | -6.71 | MODULE_47 | MSigDB lists | MODULE_47 | 219 | 49 | 17758 | 2588 |
MYL9,CD99,LTBP1,MRC2,PCOLCE,WDTC1,LMCD1,COL18A1,PDGFRL,SEPP1,FBLN1,FLII,CTGF,CALD1,ALDH1A3,COL6A1,ACTA2,RGS5,NOTCH3,EGLN3,MOXD1,LOXL1,F2R,CKAP4,CYP1B1,SGCE,COL6A2,MMD,PLAUR,KDELR3,EMP3,LOXL2,LDB2,CRISPLD2,FZD7,COL12A1,MAP1B,DPYSL3,EDNRA,TIMP3,SCG2,WWTR1,MYLK,SH3BP4,RAB31,BMP1,PLXND1,LTBP2,COL16A1 |
| 1.221e-03 | -6.71 | BROWNE_HCMV_INFECTION_16HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_16HR_UP | 219 | 49 | 17758 | 2588 |
EXPH5,RMND5A,CCNC,ENO2,FAM169A,PPP1R2,SLC25A13,SUZ12,DCAF7,TESK2,DHX8,IL27RA,PRKACA,STIL,PARM1,BMP2,B3GALNT1,BTG3,CDKL5,RGS3,DLG1,FBXL14,PDE4D,DLG3,PTPRE,HSPA2,IGSF3,LAMP3,NFE2L3,RFK,PLSCR1,HSPA12A,PLS1,RUNX3,FXR2,RNF19B,PDLIM3,KCNK1,NAT1,ATP7B,ABCB1,NR4A3,MAOA,SFMBT1,ZBTB6,IFI6,ZBTB33,NR2C2,NXT2 |
| 1.222e-03 | -6.71 | PID | prosite domains | PS01179 | 31 | 12 | 11866 | 1802 |
LDLRAP1,RGS12,TBC1D1,SHC3,ANKS1B,CCM2,APPL2,APBA1,APBA2,TBC1D4,EPS8L2,MAPK8IP1 |
| 1.225e-03 | -6.70 | PROTEIN_TRANSPORT | MSigDB lists | PROTEIN_TRANSPORT | 154 | 37 | 17758 | 2588 |
NFKBIE,PEX6,GGA1,PDIA3,APBA1,BARD1,ERP29,AIP,ZFYVE9,APPBP2,ATG4A,ZFYVE16,CALR,AP1M2,CDH1,PPP1R10,LMAN2L,KIF13B,BCL6,F2R,TRAM1,RPGR,KDELR1,MDFI,ATG4D,NAGPA,AKT1,COG2,STRADB,ICMT,VCP,OPTN,KLHL2,KPNA2,CTSA,LTBP2,ABCG1 |
| 1.225e-03 | -6.70 | GTGACTT,MIR-224 | MSigDB lists | GTGACTT,MIR-224 | 154 | 37 | 17758 | 2588 |
RUNX2,NUAK1,CIT,CAST,SDC4,KIF23,KCTD12,FTH1,NOTUM,PHLPP1,ITGA3,DPYSL2,LYPD6,FOSB,ACSL4,MYLIP,AMOTL2,NR4A1,MGAT4B,KBTBD8,COL7A1,SYP,KDM3A,MAP1B,TRIM9,SERTAD2,SLC4A4,RND3,ZDHHC20,AMMECR1,OTUB2,YOD1,NR4A2,ATP1B3,APBA2,CPEB2,CBX7 |
| 1.226e-03 | -6.70 | peptidyl-proline hydroxylation | biological process | GO:0019511 | 13 | 7 | 16441 | 2455 |
EGLN3,P4HB,P4HA2,P3H2,P4HA3,CRTAP,EGLN1 |
| 1.226e-03 | -6.70 | mesenchymal cell proliferation | biological process | GO:0010463 | 13 | 7 | 16441 | 2455 |
BMP2,CTNNB1,OSR1,FGFR2,BMP7,GPC3,STAT1 |
| 1.226e-03 | -6.70 | regulation of nephron tubule epithelial cell differentiation | biological process | GO:0072182 | 13 | 7 | 16441 | 2455 |
GATA3,PROM1,CTNNB1,OSR1,FAT4,WWTR1,STAT1 |
| 1.226e-03 | -6.70 | phospholipid scrambling | biological process | GO:0017121 | 13 | 7 | 16441 | 2455 |
P2RX7,PLSCR4,ANO9,PLSCR1,ANO4,ANO6,XKR8 |
| 1.228e-03 | -6.70 | NEGATIVE_REGULATION_OF_CELLULAR_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_CELLULAR_PROCESS | 633 | 120 | 17758 | 2588 |
CASP3,SIGIRR,ACVR1,TCF25,NF2,S100A11,CNOT8,SUDS3,XIAP,TP53,CUL1,COL18A1,FTH1,BCL2L1,TP53I11,BARD1,IER3,CDKN2C,BTG3,FABP6,FOSB,DLG1,CAPG,BCL6,CDKN1B,IRF2,TAX1BP3,TWIST1,TNFRSF18,CDKN2D,SIRT1,CDKN2AIP,BAG4,SOD1,ING1,DRAP1,SERTAD3,CDA,BNIP3L,HTATIP2,ARHGDIB,GLO1,RAD17,PRKRA,SESN1,CDK1,ARHGAP35,SOCS3,MID1IP1,KLF12,PPP2R4,HDAC1,TLE1,NRG1,IRF7,KLF11,GLA,ARF6,HSPB1,CBX4,MAPK12,GLIS3,HSP90B1,RUNX2,ARAP3,NFKBIE,CDKN1C,IGFBP6,SERPINB9,NKRF,NOTCH2,GSTP1,ETS1,RND1,BMP2,RB1,CARD8,IGF1R,TIMP1,PTEN,PAIP2B,BMP7,BAX,ATP8B1,WWP1,PIM1,HEXIM2,TMX1,OSGIN1,SOCS5,MDFI,QSOX1,TGIF1,ELK3,GCLC,FURIN,EMP3,RUNX3,EIF2AK1,NPHP3,RHOB,RASA1,BCL10,FAS,CDK5RAP1,BTG1,TSC1,SERTAD2,SCG2,SEMA4D,ACVRL1,DHRS2,CGREF1,ARAP1,E2F1,IFI6,TOB1,HIPK3,CTBP1,CD33 |
| 1.233e-03 | -6.70 | protein kinase activator activity | molecular function | GO:0030295 | 53 | 17 | 16491 | 2452 |
NKX3-1,IQGAP1,CALM1,RGCC,CALM3,CDK5R1,CALM2,PRKAG2,GPRC5B,MADD,PAK2,PIK3CA,CAB39,NRG1,EFNA5,ERBB3,SPRY2 |
| 1.236e-03 | -6.70 | positive regulation of peptidase activity | biological process | GO:0010952 | 161 | 39 | 16441 | 2455 |
CASP3,PINK1,PCOLCE,NKX3-1,DAP,PSME2,TRAF2,RET,PSME1,FBLN1,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,DAPK1,BAX,CDKN1B,WNT3A,EGLN3,F2R,SIRT1,RHOA,ACVR1C,CASP9,SLC11A2,BCL2L13,CYFIP2,VCP,FAS,BCL10,CASP7,NGFRAP1,ARRB1,GPER1,MAP3K5,MAPK12,XDH |
| 1.237e-03 | -6.70 | KINASE_REGULATOR_ACTIVITY | MSigDB lists | KINASE_REGULATOR_ACTIVITY | 45 | 15 | 17758 | 2588 |
CDKN2C,CDKN1C,DNAJC3,MADD,PIK3R1,CDKN1B,PRKAR2B,HEXIM2,CDKN2D,MAPK8IP1,CDK5R1,PKIA,PRKAR1A,BCL10,SOCS3 |
| 1.237e-03 | -6.70 | ENGELMANN_CANCER_PROGENITORS_UP | MSigDB lists | ENGELMANN_CANCER_PROGENITORS_UP | 45 | 15 | 17758 | 2588 |
SFXN1,CD55,CYP1A1,KCNN4,SLC2A6,ABCG2,LMCD1,FHL2,CTSZ,ANXA9,GEM,MAST4,MYO5A,IRX3,B4GALNT1 |
| 1.237e-03 | -6.70 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | 45 | 15 | 17758 | 2588 |
BIN1,TIMP3,ITGA3,SOX9,SH3BP4,BMP1,STEAP3,TNFRSF12A,CD70,JAG2,BCL2L1,F2RL1,CARD10,GCNT1,SEMA3B |
| 1.240e-03 | -6.69 | Furin-like | pfam domains | PF00757 | 7 | 5 | 16629 | 2504 |
ERBB2,INSR,ERBB3,IGF1R,EGFR |
| 1.240e-03 | -6.69 | Recep_L_domain | pfam domains | PF01030 | 7 | 5 | 16629 | 2504 |
ERBB2,INSR,ERBB3,IGF1R,EGFR |
| 1.241e-03 | -6.69 | HELLER_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_SILENCED_BY_METHYLATION_UP | 275 | 59 | 17758 | 2588 |
DDX58,PACSIN2,AGRN,NQO1,IL15,FOXM1,TSPAN15,ARL4C,GATA3,DHX8,IL13RA1,CNTNAP2,GPSM2,SNN,CCNB1,HERC6,BMP2K,SIRPA,ICAM1,IER3,TOP2A,CDH1,METTL7A,DOK4,CAPG,BCL6,BUB1,ARNT2,IFIT1,PIK3CD,CLIP2,S100A13,APOBEC3G,S100A6,CYP1B1,LAMP3,MX1,PLK1,ALDH2,S100A4,USP18,CDC20,SAT1,PTGER4,CCNF,IFIT3,RNF19B,ALCAM,MAP3K6,LCP1,ATP13A2,SOCS3,IRS2,STAT1,NR4A3,ARRB1,AURKA,IFIH1,L1CAM |
| 1.243e-03 | -6.69 | REACTOME_COLLAGEN_FORMATION | MSigDB lists | REACTOME_COLLAGEN_FORMATION | 54 | 17 | 17758 | 2588 |
COL9A3,ADAMTS2,PCOLCE,COL6A2,COL4A5,COL7A1,COL12A1,PLOD2,P4HB,COL13A1,COL6A1,BMP1,ADAMTS14,PLOD3,COL16A1,CRTAP,TLL2 |
| 1.243e-03 | -6.69 | OUILLETTE_CLL_13Q14_DELETION_DN | MSigDB lists | OUILLETTE_CLL_13Q14_DELETION_DN | 54 | 17 | 17758 | 2588 |
ENO2,SERPINE2,BACE1,ETV5,BIK,MYBL2,CYB561,PHLPP1,DDR1,TRIM7,ULK2,CDK5R1,DDAH1,SIPA1L2,PKD2,ESYT2,PARP9 |
| 1.250e-03 | -6.68 | EGFR (epidermal growth factor receptor) | protein interactions | 1956 | 835 | 165 | 16036 | 2547 |
FAF2,SLC25A13,CUL4B,RET,ARFGEF1,DNAJB11,CDIPT,OAT,HDAC6,SNX9,SH3KBP1,PLS3,PCNA,PSMD1,AP1M2,CTNNB1,CTGF,SHC3,P4HB,ARL1,DNM2,TUBG1,CTTN,TECR,CERS2,TUBA4A,PLK1,PTPN18,SH3BGRL,ITCH,EZR,CDK1,ARF4,PRIM1,TNS4,PLCG1,AREG,DNM1L,SH2D3C,LRIG1,CTNND1,PIK3C2B,ARF6,GAB1,GRN,INPPL1,LGALS3,UBASH3B,PRKAA1,CALM3,PDXDC1,ELF3,CALR,TNS3,DOPEY2,IGF1R,PFKL,RANBP1,EXOC8,PIM1,NCAM1,SLC12A2,PPP6R1,NUP85,ALDH3A2,SOCS5,FADS2,ADCK3,CALM1,PDK3,EGFR,RASA1,FAS,PTPRF,GNAS,HTT,PITPNA,MDH1,PLD1,CTBP1,RPS6KA3,EHD1,TUBB4B,CD82,TP53,ERBB2,PRKACA,PHLDA1,GNB2,CCND1,C11orf84,CDH1,DOK4,PLCG2,TNPO2,GOT1,FAR1,FLOT2,HSPA2,DOCK4,MAP3K3,SEC61B,AKT1,LGALS8,S100A4,VPS4B,ATP1B1,CBL,CDC25C,ALCAM,SOCS3,IRS2,PTPRJ,ATP1A1,JAK1,STK26,STAT1,NRG1,RPL22,ARFGEF3,PRKAR1A,WASF3,COL9A3,GCLM,HSP90B1,ANKRD13D,TOR4A,CKAP2,RUSC2,ARHGEF7,TRAF2,EPS8,PDIA3,PLD2,FBXO6,SEPP1,AIP,ICAM1,H1FX,PPP2R3A,HLA-A,SGPL1,ADRBK1,ANKS1B,ACTA2,ERBB3,IQGAP3,SPRY2,SYK,ATP2B1,CAMK2G,FAH,MOB4,PLSCR1,NR3C1,PIK3R1,AK4,YES1,FOS,MAPK8IP1,ACADSB,ARRB1,NCAPG2,NDFIP1,PKIA |
| 1.251e-03 | -6.68 | VERNELL_RETINOBLASTOMA_PATHWAY_UP | MSigDB lists | VERNELL_RETINOBLASTOMA_PATHWAY_UP | 68 | 20 | 17758 | 2588 |
SUZ12,SNTB2,EPS8,PBX3,POLD3,BARD1,FAM111A,BTG3,PCNA,CDCA4,KCNK1,SPIN4,ZNF367,DCK,CDCA5,CDCA7L,KANK2,DONSON,CNOT6L,MELK |
| 1.255e-03 | -6.68 | GSE14000_4H_VS_16H_LPS_DC_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_UP | 181 | 42 | 17758 | 2588 |
DDX58,PLA2G4A,EPAS1,PARP14,DAP,UBASH3B,BLVRB,NDUFA4,FAM198B,GALM,MGST2,ASPHD2,ATP5H,ATP13A3,H2AFY,CLDN4,IL17RA,AHCY,KLF9,TECR,LMAN1,IL1RAP,OSGIN1,S100A4,MPP1,PTPRH,PARP4,ATP1B1,PDK3,ESYT1,CBL,SLC25A5,HTT,RIN3,DTX4,SLC27A1,SPCS3,RPL22,LTA4H,RTN3,RARG,CD33 |
| 1.264e-03 | -6.67 | Rho GTPase binding | molecular function | GO:0017048 | 81 | 23 | 16491 | 2452 |
DOCK4,SOD1,RALBP1,IQGAP1,EPS8,DIAPH2,STRADB,NCKAP1,PKN1,DOCK11,ARHGEF16,PAK6,NOXA1,CDKL5,CORO1C,OCRL,PAK2,TRIOBP,MAP3K11,IQGAP3,ARHGAP4,ITPKA,DOCK9 |
| 1.268e-03 | -6.67 | IKBKG (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma) | protein interactions | 8517 | 290 | 66 | 16036 | 2547 |
AVPI1,NLRX1,TRIM5,RALBP1,RET,EPHA4,LMCD1,CUL1,FLT3,CARD10,CPNE2,TUBG1,EGLN3,NFKB2,PLK1,RIPK2,AKT1,TNIP1,NRBF2,RNF11,GLO1,PRKCQ,ZFAND5,GINS4,FYN,MPRIP,TRIOBP,NOD2,ABCA1,DDX58,HSP90B1,TAB3,PARP14,PLEKHJ1,TRAF2,PDCL,KIF23,RACGAP1,TEC,TMA16,MERTK,AIP,SSX2IP,MYO5C,MZT2A,CARD8,PHF7,IRAK1,NECAB3,PRKCI,DAPK1,SGK1,WWP1,MAP3K7,RHOA,SHARPIN,VAMP3,EGFR,BCL10,NCOA3,H1F0,HTT,NFKBIA,AURKA,JAK3,RUSC1 |
| 1.276e-03 | -6.66 | phospholipid translocation | biological process | GO:0045332 | 20 | 9 | 16441 | 2455 |
KCNN4,ATP8A1,ATP9A,TMEM30A,P2RX7,ATP8B1,ATP8B3,ABCA1,ATP10D |
| 1.276e-03 | -6.66 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_DN | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_DN | 192 | 44 | 17758 | 2588 |
ELK4,LZTFL1,INPPL1,TXN,FAM92A1,TTC39B,IL15RA,LGALS3,BVES,DHPS,SEC61G,FLYWCH2,RHBDL3,GATA3,NDUFA4,PLD2,CHST2,SDF4,ICAM1,EPDR1,SNTA1,RB1,BMP7,PRC1,ECI2,KIF22,MDFIC,CTTN,F2R,GFI1,SLC39A8,S100A4,SAT1,CDA,CASP4,FRMD4B,SOCS3,CSF1,ABCB1,RYK,OTUB2,PPP2R3C,TMEM159,ABCG1 |
| 1.276e-03 | -6.66 | GSE3982_MAC_VS_TH2_UP | MSigDB lists | GSE3982_MAC_VS_TH2_UP | 192 | 44 | 17758 | 2588 |
ACACB,SLC25A24,CEP70,FRMD4A,REPS2,GNPDA1,CAST,ETV5,NDRG2,ITPR2,PLXNA1,NTAN1,MAP1LC3B,DNAJB9,SNX13,LRRC6,PAPSS1,ACOX2,SPRY2,ALDH3A2,EPHX1,SOCS5,ENPP4,DCAF6,MMD,LGALS8,NRBF2,ACO1,SERTAD3,SLC11A2,FXR2,IFIT3,PDHX,STEAP1,BCL10,FUCA1,TSC1,SWAP70,PRKAG2,TIMP3,PRCP,RHOBTB2,FZD5,GOLGB1 |
| 1.276e-03 | -6.66 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | 192 | 44 | 17758 | 2588 |
CASP3,NUDT6,GAA,LASP1,FAM129B,STRN4,NDUFA4,BLCAP,IL18R1,SLC25A35,XPR1,WWP2,EPCAM,AP1M2,ELF5,FAM13B,DRAM1,TRIM3,POF1B,TACSTD2,ACOX2,PTPRE,TMBIM1,TMED2,CKAP4,PARP9,CYP1B1,ADAM17,SEC61B,SCRIB,NPC2,KCTD2,PLEKHB1,IL1R1,H1F0,C19orf66,ITGA7,DBI,APPL2,MRPS28,ALG2,RBM43,SRSF9,ACOT7 |
| 1.276e-03 | -6.66 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 192 | 44 | 17758 | 2588 |
FARP1,SPC25,FOXM1,TBC1D1,ARHGEF7,ERI2,C5orf30,EGR3,PHLPP1,STIL,KCTD9,FANCI,BTG3,CEP97,SIVA1,UBE2J1,RFX5,PPP1CA,FAIM,GFI1,PSMA5,PCCB,TIMP2,PLSCR1,C3orf52,CDC20,EZR,GGH,LRRC1,ICMT,DCP2,FECH,PLCH1,TMEM164,PEX5,FAM64A,CDK19,DBI,CENPE,ATP1B3,UBE2C,CBX5,E2F8,ACOT7 |
| 1.276e-03 | -6.66 | GSE17721_LPS_VS_PAM3CSK4_8H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_8H_BMDM_UP | 192 | 44 | 17758 | 2588 |
GRN,RUNX2,NDRG1,HMGN3,FAM198B,LGALS3BP,MXD1,CDK14,CAPN2,DOPEY2,PDCD10,ZFP36,SLC44A2,H2AFY,CDKN1B,ECE1,MINPP1,SNX10,DUSP1,ENPP4,PMPCB,HMGN5,NRBF2,STAT4,PLEKHO1,SAT1,VAMP3,SERTAD3,CCBL2,SPTLC2,RNF19B,PSMA4,HLA-B,PLEKHG6,SWAP70,ATXN7L3,CSF1,RAP2C,GLA,PLOD3,RGS14,ST3GAL1,ANXA11,RAD21 |
| 1.276e-03 | -6.66 | GSE17721_POLYIC_VS_CPG_4H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_4H_BMDM_UP | 192 | 44 | 17758 | 2588 |
KLF2,S100A11,CHCHD7,RALBP1,GATA3,CAMK1D,PJA2,BARD1,PSIP1,EPS8L2,RB1,CTNNB1,ZNF823,FRYL,SORL1,SGK1,TSPAN13,MINPP1,TMEM8A,NAGA,DPYSL5,ERMP1,PSRC1,B9D2,GCLC,DBR1,HTATIP2,AKR1E2,ZDHHC3,ULK2,C18orf8,FUCA1,CD8A,DNAJC10,PELI2,DOLPP1,SECTM1,RELL1,PDXK,RAP1GAP,PRR15,GAB1,IRF1,ABCG1 |
| 1.278e-03 | -6.66 | TMOD1 (tropomodulin 1) | protein interactions | 7111 | 19 | 9 | 16036 | 2547 |
MYO5B,PRKAA2,FLII,LRRFIP2,EFHD2,TBC1D4,NEB,NIN,MYO5C |
| 1.278e-03 | -6.66 | VAV3 (vav 3 guanine nucleotide exchange factor) | protein interactions | 10451 | 19 | 9 | 16036 | 2547 |
PLCG1,ZYX,INSR,RHOA,IGF1R,PIK3R1,ERBB2,ERBB3,EGFR |
| 1.278e-03 | -6.66 | negative regulation of protein complex disassembly | biological process | GO:0043242 | 62 | 19 | 16441 | 2455 |
GAS2L1,ADD1,CKAP2,DMTN,EPS8,AURKB,CCNB1,HDAC6,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,CAPG,TRIOBP,AURKA,TMOD2,SPTBN5,SHROOM2 |
| 1.280e-03 | -6.66 | RAO_BOUND_BY_SALL4_ISOFORM_B | MSigDB lists | RAO_BOUND_BY_SALL4_ISOFORM_B | 496 | 97 | 17758 | 2588 |
ARHGAP11A,CASP3,PAX6,IBTK,TRIM5,VANGL1,CNOT8,EPHA4,CCDC68,CD274,MORF4L2,OSR2,BARD1,CENPN,NKAIN3,C11orf84,RCN1,CTNNB1,LMO4,STEAP2,SNX16,CLDN4,STK35,UPF3A,CLCN3,CD55,FIGNL1,ASXL1,NFE2L1,KIF13A,PIF1,ANLN,ANKRD10,HLF,ANKRD6,GDE1,HS3ST3B1,SPRY4,RTN3,MYL12B,CBX7,ANXA11,DDX58,RMND5A,CMAS,GCLM,ARHGEF3,PACSIN2,MPZL1,RUSC2,CENPI,HABP4,ETV5,PSMD7,ABCG2,ZNRF3,ZNF219,TNFRSF19,LBR,HMGXB4,SLC25A36,HDAC9,SPP1,ITGA3,LRRN2,PPP1R10,OSTF1,KLF9,NPTN,CITED2,ZRANB1,GAD1,ALDH3A2,CCDC88A,SOCS5,PCCB,HES1,TGIF1,CASK,B3GNT2,SALL4,SRSF5,BCAR1,TCEAL8,C3orf58,G2E3,BCL10,PITX2,DCTN6,NAT1,TBX18,SH3BP4,MAP3K5,CBX5,CPEB2,RNF146,DIS3L |
| 1.282e-03 | -6.66 | regulation of protein depolymerization | biological process | GO:1901879 | 76 | 22 | 16441 | 2455 |
GAS2L1,ADD1,CKAP2,DMTN,DSTN,EPS8,NES,AURKB,CCNB1,HDAC6,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,CAPG,TRIOBP,AURKA,TMOD2,SPTBN5,SHROOM2,F2RL1 |
| 1.284e-03 | -6.66 | RHO GTPases activate IQGAPs | REACTOME pathways | R-HSA-5626467 | 13 | 7 | 8202 | 1235 |
CALM2,CALM3,IQGAP3,CTNNB1,CDH1,IQGAP1,CALM1 |
| 1.284e-03 | -6.66 | Trafficking and processing of endosomal TLR | REACTOME pathways | R-HSA-1679131 | 13 | 7 | 8202 | 1235 |
CTSL,UNC93B1,HSP90B1,LGMN,CNPY3,CTSB,CTSV |
| 1.288e-03 | -6.65 | V$TEF1_Q6 | MSigDB lists | V$TEF1_Q6 | 214 | 48 | 17758 | 2588 |
PRKAA2,AVPI1,FRMD4A,VANGL1,MAN1A2,ABCG4,CDCA3,GATA3,NES,NOTCH2,TMPRSS4,PRRG4,EPS8L2,SYTL2,CYP26A1,C1orf116,LMNA,ELF3,CD109,CDKN2C,ST5,SCNN1A,ADD3,CYR61,CKS1B,TINAGL1,WNT3A,NFKB2,DENND1B,ATP1B1,KDM4D,RASGRP2,MAPKAPK2,PTPRF,PIAS3,MDK,SWAP70,PTPRJ,FGFR2,MADD,C1orf21,OVOL1,PRKCDBP,ADIPOR1,ZMIZ1,HOOK1,RTN3,EHD1 |
| 1.313e-03 | -6.64 | gastrointestinal_stromal_tumour | COSMIC cancer mutations | gastrointestinal_stromal_tumour | 78 | 22 | 17775 | 2585 |
ERMP1,AKT1,ATP9A,CASP9,TP53,NUCB2,IDH1,FLT3,BCAR1,GNA11,EGFR,GNAS,RB1,INSR,CTNNB1,CDH1,PTEN,PFKL,SLC2A6,ABCA2,PIK3CA,LZTS1 |
| 1.313e-03 | -6.64 | MODULE_72 | MSigDB lists | MODULE_72 | 304 | 64 | 17758 | 2588 |
MYL9,SUZ12,PTTG1,TMX4,KIF2C,PLA2G16,CHPF,ZYX,BTG3,PCNA,ST5,HSF2,PSMC2,DNM2,CPE,HSPA2,CKS2,PLK1,SMARCA2,SGCE,COL6A2,SEPT6,CDC20,PKMYT1,ITPR3,GTF2A2,PLCG1,TRAM2,GPRC5B,WFS1,MYLK,PPP2R5D,PCOLCE,ITGA6,DNAJB2,SOX9,CALB2,TRIB2,HMGXB4,CKAP5,SAC3D1,TOP2A,MDM1,CDK16,NECAB3,PPP4R1,PRKCI,NEK2,SRP54,IGFBP2,DLX4,GFPT1,GCC2,QSOX1,ZWINT,TCFL5,FHL2,AKAP3,SRSF5,PSMA4,TCEAL4,RAB31,CCNB2,JARID2 |
| 1.314e-03 | -6.63 | morphogenesis of a branching epithelium | biological process | GO:0061138 | 172 | 41 | 16441 | 2455 |
ACVR1,NKX3-1,GRHL2,TMTC3,ST14,SOX9,CTSZ,PLXNA1,GBX2,BMP2,CTNNBIP1,CTNNB1,NPNT,BMP7,GPC3,DLG1,BAX,PPP1CA,SLC12A2,ETV4,SPRY2,DCHS1,TFAP2C,ILK,DAG1,EDNRA,SOCS3,NCOA3,FAT4,AREG,FGFR2,CSF1,SPINT2,PKD2,HOXB13,PLXND1,SOX8,FZD5,SEMA3A,FOXA1,ADAMTS16 |
| 1.314e-03 | -6.63 | microtubule associated complex | cellular component | GO:0005875 | 143 | 35 | 17570 | 2579 |
DYNLRB1,KIF3C,KLC2,CDCA8,KIF23,KIF2C,HDAC6,DNAH3,KIF26A,APPBP2,KIF5B,DNAH6,KIF14,KIF13B,KLC3,KIF22,CLIP2,DNAI1,KIFC2,KIF20A,KIF1C,KIF13A,KIF20B,AURKB,KIF11,RANBP9,MAP1B,DCTN6,FNTA,MAP2,AURKA,SPTBN5,CENPE,KIF12,NDE1 |
| 1.315e-03 | -6.63 | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 176 | 41 | 17758 | 2588 |
ARHGEF3,RUNX2,NFKBIE,LMCD1,FLOT1,GRK6,CENPN,PRRG4,HLA-A,ASPHD2,DTX3L,TRANK1,CTSC,RGS3,MITF,FAR1,CAMK2G,PSMA5,TUBA4A,PARP9,PCGF5,TRIM8,TACC1,LAP3,DENND1B,SNTB2,SAT1,NFE2L1,SERTAD3,UTRN,TCN2,GALNT3,ZDHHC20,SECTM1,NMI,PLEKHG1,CCDC69,DYSF,IFIH1,MAFF,DLAT |
| 1.320e-03 | -6.63 | phospholipid binding | molecular function | GO:0005543 | 349 | 73 | 16491 | 2452 |
PLA2G4A,DOC2A,MTM1,IQGAP1,DGKA,ITPR2,SYTL4,SNX9,ZFYVE9,SYTL2,ZFYVE16,PASK,SNX16,DAB2IP,PACSIN1,TIAM1,SNX10,RASGRP1,SNX8,MCTP1,MARK1,AKT1,ESYT1,ITPR3,SNX12,SEC14L2,WIPI1,AXL,PIK3C2B,ANXA9,SYT13,PXDC1,NRGN,TC2N,ABCA1,ANXA11,ANXA3,ARAP3,PACSIN2,MCTP2,PLD2,RACGAP1,TEC,APBA1,FAM21C,SNX13,WDFY1,SNX18,MCF2L,PRKCI,SGK3,ATP8B1,PLEKHF1,TTPA,SYTL3,CCDC88A,SNX7,ARAP2,RAPGEF2,AMER1,PCTP,CPTP,LDLRAP1,SYT7,ITPR1,PLA2G15,ARAP1,DYSF,PLD1,WDR45B,SNX30,ESYT2,ABCG1 |
| 1.321e-03 | -6.63 | DODD_NASOPHARYNGEAL_CARCINOMA_DN | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_DN | 1265 | 222 | 17758 | 2588 |
FAF2,IL15RA,TRIM24,GNPDA1,SLC25A13,NDC80,UBE2Z,CUL1,PDGFRL,KIF2C,PLXNA1,CCNB1,CENPN,FANCI,MAGOHB,BTG3,PCNA,UBE2T,NPNT,DPYSL2,CEP78,SLC44A1,ARNT2,SLC39A10,FGFR1OP2,LAMP2,CENPA,MARK1,LAP3,PBK,USP18,RNF165,C12orf65,CCNF,ANLN,LHFPL2,IDH1,CDK1,TRUB1,RHEB,PRIM1,SFXN1,TRAM2,MSL1,FASTKD1,DNM1L,ZNF367,DHTKD1,KPNA2,STARD3NL,DDX58,RECQL,PARP12,FRMD4A,HJURP,NUAK1,ADO,ASB9,KIF23,RACGAP1,SLC1A3,CNTNAP2,ZNRF3,PM20D2,GPSM2,PGAP1,SSX2IP,FRAS1,RANBP1,SLC30A6,NEK2,MSH2,AHCY,KNTC1,GAD1,NUP85,MPHOSPH9,KCTD3,MCCC2,CKAP4,SOCS5,MMD,ZNF84,KIF20A,USP31,ANO6,WHSC1,VEZT,KIF20B,IFIT3,ANKRD29,PSMA4,FAS,FNTA,FAM64A,OTUD6B,CDCA5,DCUN1D1,FGD6,AURKA,DONSON,ZDBF2,NDE1,AKIP1,IFIH1,CBX5,CCNB2,AFAP1,EGLN1,RAD21,CCNE2,ARHGAP11A,FOXO6,UPF3B,DLGAP5,PAPSS2,IL15,FOXM1,SUZ12,PTTG1,ETNK1,MORC4,NUF2,CD274,FAM198B,RCN1,C11orf84,NOV,CCNA2,KIF14,PLK4,RPN2,ACSL4,OAS3,RNASEH2A,EPHB4,MINPP1,LMAN1,F2R,SNX10,SEPHS1,CKS2,PPIF,DOCK4,GCA,TAF5,PSRC1,KREMEN2,RIPK2,FIGNL1,PANK1,CDCA2,NUSAP1,B3GALNT2,CDC25C,ZNF618,FZD7,PTGS2,RBL1,NGFRAP1,AXL,STAT1,TLE1,RPL22,SGOL1,TM2D2,MPZL1,DEPDC1,CKAP2,SCD5,CENPI,ERCC6L,INTS8,POMGNT1,NTAN1,ARHGEF40,TIPRL,ICAM1,HMGXB4,SAC3D1,CKAP5,SLC25A36,SCML1,TOP2A,PTEN,CTSC,CENPJ,CALD1,FJX1,PRC1,GTF2F2,DRAM1,CKS1B,ACTA2,BUB1,IQGAP3,MSH6,SMC4,HMMR,NFE2L3,B3GALT6,ADAMTS2,CASK,ZWINT,DCAF6,ZC3H11A,ASPM,EIF5A2,C2orf69,KIF11,CRISPLD2,CNOT2,TWSG1,NEIL3,SLC25A40,E2F1,CENPE,ITGAV,NUP37,NCAPG2,UBE2C,MELK |
| 1.327e-03 | -6.62 | serous_carcinoma | COSMIC cancer mutations | serous_carcinoma | 11513 | 1742 | 17775 | 2585 |
HECA,FAM160B1,IBTK,GRIK2,AK7,HEXB,RET,CCNO,TRAPPC8,BAIAP3,ISOC2,LACTB2,DPP8,FAM46C,CARD10,LTBP3,SLC35E4,ZNF275,GRM5,CDKN2C,MUC4,PAQR5,ATP13A3,DNM2,TMEM37,RNF26,TIAM1,IL10RB,CPE,TIPARP,MGAT5,NEK4,FBXL16,DSTN,CDA,TMEM98,KDELR3,PRKAR2B,RNF19B,PNKD,ABR,LCP1,ENPP1,PLCG1,MPRIP,ATP7B,CELF5,TRAF3IP1,FAM114A1,NOD2,HDAC1,TMOD2,RNASEL,STARD13,HSPB1,ANXA11,NXT2,SCN5A,GGA1,ITGA6,MTL5,RAB23,FAM21C,RABGGTA,MARCH8,TFAP4,FLII,ZCCHC17,FRY,MEGF8,FLRT3,FBXO7,RANBP1,FBXL14,MAP3K9,CADPS2,USP1,USP38,FAM84B,ALPK1,CNGA1,PANX2,MAPK7,MOXD1,MYLIP,DGKG,NUP85,PHKG2,TTLL1,MCCC2,HPS3,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,SFXN5,PSMA4,GNA11,MAGED2,IL1R1,CACHD1,FNTA,SLC4A4,ETS2,RAET1L,CLMN,OSCP1,GDF11,TMEM159,RUSC1,ADAMTS16,DMPK,DOCK9,WDR63,NQO1,LFNG,CD82,RHBDL3,GRK6,MGST2,FAM91A1,MOCS1,REPS1,KIAA1147,RCN1,RBM23,MUC16,ST5,CDH1,XYLT2,ENPP5,RASGEF1A,DLG3,ZNF365,ETV4,MYT1,TMEM200B,MX1,SNX8,COL6A2,ERMP1,C6orf1,RIPK2,APOBEC3D,PFKFB2,AGPS,VPS4B,HTATIP2,SYP,XRCC6BP1,TANC1,ZNF618,SNX12,TRIM7,EBF2,GIGYF1,SPIN3,PDLIM3,CCNB3,SHROOM3,CDK19,WFS1,AXL,PNPLA6,FAM149A,MAPK12,CTHRC1,HSP90B1,MPZL1,CKAP2,BACE1,TRAF2,BIK,HABP4,CCM2,BTN3A1,ZNF219,SLC25A43,NFAT5,BEX2,CTNNBIP1,DIRAS3,ZFX,IGSF9,KNDC1,GPC3,MGAT4A,TMEM62,CST3,TUBGCP6,FAM20B,BAX,KLC3,FAM102A,RAG1,CASD1,MED22,PARP9,PVRL4,ADAMTS2,PLSCR1,TACC1,PIK3R1,CXorf57,AK4,PGBD1,RAB3IP,C4orf27,CNTNAP1,PROM1,LDLRAP1,PLOD2,SYT7,SLC35B3,FAM3C,PLA2G15,PPM1H,FBXO44,ITGAV,OSR1,PHC1,TLL2,TMEM131,CCNI,TNK1,BCAM,KIAA1462,EPAS1,ARFGEF1,LMCD1,DNAJB11,TEX2,F11R,MGAT5B,ITPR2,SPTB,FANCI,PLS3,SUSD2,BTG3,CPNE2,ENTPD4,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,NPNT,IL6ST,PAPSS1,SLC44A1,MITF,NTN4,SCARA3,PLK1,KRT80,PTPN18,MARK1,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,CCBL2,CKAP2L,NKAIN1,SESN1,DZIP1L,KDM4D,TRIM9,TNS4,PLEKHG6,PI4K2B,TRAM2,KLF12,TXNRD3NB,KLF11,KPNA2,TTC39C,TC2N,HS6ST3,RRAGD,RMND5A,PARP12,RUNX2,USH1C,HJURP,RASA2,PSMD7,ADCK5,HES2,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,UBE2Q2,RINL,FRAS1,KIF13B,ICAM5,SLC30A6,PIM1,WNT3A,MPHOSPH9,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,ZNF320,MGAT4B,STRADB,SCRIB,PDK3,BCL2L13,CDK5R1,PRX,NMT2,C18orf8,RASGRP2,COL13A1,OTUD6B,PHLPP2,P4HA3,SLC2A6,NLRC5,ZDBF2,PLD1,SEMA3A,CDAN1,USP43,RAD21,TP53,RHPN2,P2RX7,BAHD1,EMP2,STIL,BCAP31,SYTL2,IER3,TTC21B,WDR44,TACC2,BCL6,ZDHHC23,PLK4,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,CLCN3,ERLEC1,AKT1,ACO1,C3orf33,DAG1,ATP13A2,PTGS2,TAPBP,IDE,PTPRJ,PAFAH1B3,ABHD12,RBL1,STK38,MAOA,CHMP4B,XRCC3,SYT13,ARHGAP4,FAM134B,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CDH22,CPEB4,TAB3,KLHL13,SCD5,GNAL,MCTP2,HAL,CDCA8,ERCC6L,ERI2,LBR,PARM1,H1FX,NRP2,CD109,FOXP2,ALPP,CDK16,GTF2F2,FAM63A,IL17RA,TRIM21,SGK1,TSPAN13,ALDH7A1,HMGCL,SYK,FAM134C,ATP2B1,WBP5,DUSP1,NFE2L3,HES1,FBLN5,RHOA,MOSPD2,GUSB,PLAUR,STMN3,PRICKLE1,MAML2,COL7A1,RNPEP,BBS2,DGKE,BCL10,USP6,DDX23,CNOT2,DDAH1,SMTNL2,SCG2,NEIL3,NIPSNAP3A,HIPK3,ARHGEF9,ZBTB33,PKIA,ARHGEF4,GOLGB1,FAM171B,PNISR,LGR4,SSH1,HSPG2,VANGL1,C1orf198,CUL1,PSME1,CAMK1D,NANS,SEPT4,VASH1,PJA2,SLC9A7,ASPHD2,PAK6,TYMP,CYP1A1,ANKS6,ZNF823,OSBPL3,FOSB,SERINC2,KCNS3,PIK3CA,IRF2,SNX16,MARCH2,ARMCX6,METAP2,SGCE,SPATA18,ACVR1C,SLC35C1,KIF13A,LDB2,POR,RAB2B,GDE1,SH2D3C,PPP2R4,LRIG1,PRDM5,BMP1,MAPK13,NFKBIZ,SPRY4,FGD1,RECQL,MRC2,TBC1D1,PRKAA1,APBA1,S100A2,TSPAN7,SH3RF2,MESDC2,CALR,DOPEY2,RALGPS2,AIM1,MSH2,DAPK1,PRKG1,ADCK2,C8orf58,CACNA1D,KCTD3,ZNF117,SYTL3,GPR161,SOCS5,TRAK2,GCC2,KCNJ12,PRSS23,CEP89,ADCK3,LPGAT1,DCHS1,PYGL,WHSC1,ATP8B3,ANTXR1,PDE11A,MMP15,SLCO4A1,PLEKHH2,TJP3,FAM64A,FAAH,PELI2,ZDHHC20,MATN2,PIAS2,MPP2,FAM83D,APPL2,ARAP1,AGBL5,SFMBT1,CABIN1,CDK18,KLK7,ZBTB34,PER3,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,SPRED1,KIF3C,TCF25,TCTN2,DLGAP5,GPR107,REPS2,CAPN12,ST14,THRA,DDIT4L,NDRG1,CERCAM,ATP2C2,FAM78A,FTH1,TMEM19,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPM2A,CD46,APOBEC3B,NOV,CCNA2,ACAP2,TRANK1,RALB,EPHB4,PDE4D,TSPAN1,SULT2B1,ATG4D,DOCK4,COG2,FOXJ2,UTRN,KIF1C,PKMYT1,ATP1B1,PYGO1,B3GALNT2,CBL,ITPR3,ASB13,ALCAM,ATP10D,FZD7,ZMPSTE24,DDOST,POPDC3,ACAD10,CCDC149,TSPAN18,TRIOBP,SLC27A3,COBL,CBX7,MAMDC2,IGFBP6,HAPLN3,EPS8,CBLL1,NES,HERC5,PLD2,FBXO6,DNAH3,EFNB1,HLA-A,WWP2,CKAP5,SCML1,RASSF8,E2F7,TMEM87B,RNF128,FUT8,DRAM1,CD9,CCDC82,ERBB3,TTPA,MSH6,FARP2,TGIF1,PDGFC,ALDH2,B3GNT2,LONRF3,PAPD7,ZKSCAN2,FBXO9,DIAPH2,YES1,GRTP1,FOS,KIF11,CDK5RAP1,CRTC2,DCTN6,ACADSB,DGCR2,FGFR2,TBX18,ABCB1,ERAP1,WDR62,WDR91,FZD5,ESPL1,DEF6,MELK,FAF2,UGT8,UBE2Q1,VARS2,MPP5,PLAC1,COMMD5,TRIM68,ADPRHL1,ZFYVE16,RAB15,SIPA1L2,CDKL5,CASC4,ARHGEF37,ANKFN1,CEP78,TRPC1,ASH2L,CTTN,MYRIP,BTBD3,STK35,LAMP3,CYP1B1,NLRP4,ASXL1,ITCH,USP18,RGAG1,TYSND1,MAN2A2,GPRC5B,HPSE,MADD,TDRD7,SH3GLB2,ZNF165,RBM43,CAPN1,PCSK5,ARAP3,PPP1R12A,SERPINE2,ETV5,ABCG2,CALM3,FAM81A,ADAMTSL4,DUSP5,QSOX2,SPP1,TYW3,B3GALNT1,CES2,NOXA1,PFKL,OCRL,COL6A1,MTMR10,PRKCI,SRP54,LIMCH1,BRAT1,C10orf54,ZRANB1,ETV7,GAD1,SLC12A2,CCDC88A,SNED1,SNX7,ELK3,PODXL2,KIAA1109,HEATR5A,NUBP1,PDIK1L,C3orf58,STEAP1,MFSD7,SOX13,INSR,UAP1,TMEM30A,SPAG7,DCUN1D1,SH3BP4,DONSON,CTSA,C17orf75,SHROOM2,TMEM14A,JAK3,TOB1,COL16A1,RARG,DRD1,LMO7,NCKAP5,PAX6,SORBS1,HDAC11,PDIA5,COL18A1,IL27RA,MRAS,OSR2,EXT2,MXD1,SAP130,ZNF687,CYP4F11,KIF14,REEP1,ZBTB49,DIXDC1,EPB41L4B,ECE1,NFKB2,UPF3A,EBAG9,PTPRU,GLO1,CD40,TMTC2,FANCE,PDHX,CASP4,HSF4,STAT6,TLE1,SPTBN5,ABCA1,KDELC2,GLIS3,GCLM,ENO2,ARHGEF11,ARHGEF7,SHPRH,SH3D19,SERPINB9,TGFBR1,COL4A5,INTS8,TRIB2,SBF1,XPR1,HMGXB4,ITGA2B,HDAC9,SYDE2,TMEM63A,KIF5B,TOP2A,TAF1B,ADRBK1,LLGL2,BMP7,TOX2,RRBP1,H2AFY,CLIP2,RPGR,MYO5A,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,TTC7A,RUNX3,NDRG3,TCEAL8,LEPR,FOXL1,ARHGAP24,CD8A,CASP7,SWAP70,RAP2C,SPINT2,CSGALNACT1,DTX4,UACA,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,DOC2A,ACACB,KLK10,TRIM24,ADD1,AASS,MRPS15,TRIM5,XIAP,CACNA2D2,SMARCAL1,DHX8,FAM102B,NRG2,LYNX1,LGI3,MORF4L2,SYTL4,CNTROB,PHF1,EPDR1,CALM2,DAPK2,TP73,WEE1,PSMD1,TGFBR3,RGS12,AP1M2,PQLC2,DNAH6,RDH14,KLF3,ALDH1A3,FUT1,TUBG1,SEMA3G,PIK3CD,MANF,ODF2L,APOBEC3G,ERAP2,TUBA4A,NWD1,SPEF2,SMARCA2,TNIP1,SH3BGRL,SERTAD4,LOXL2,ICMT,MYOM1,CYP4F3,COL12A1,PGF,TRIM47,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,ARF6,GAB1,E2F8,ALDH6A1,TMTC3,CYP2J2,STRN4,SLC36A4,ZNRF3,MERTK,LMNA,RAVER2,ELF3,FAM189A1,CD22,PRICKLE4,ZIC5,FAM13B,NEK2,STT3B,NCAM1,C9orf72,EPHX1,NAGPA,SALL4,STAT4,MYBL2,CALCRL,MEST,SPTLC2,DCP2,RHOB,STK17A,DHX32,PTPRF,SCARB2,NCOA3,MTFMT,HTT,SEMA4D,SETD3,ITPR1,DYSF,AURKA,OSMR,MDH1,ALG2,FBXO27,ARPC2,NDE1,DRP2,SERPINB1,ZNF502,TRPC3,RPS6KA3,CSRP2,XDH,EGLN1,MTM1,CCDC109B,GRHL2,PAPSS2,GALNT12,ACTR8,WDTC1,RGS20,ETNK1,TESK2,PKP2,NUF2,PRKACA,APC2,TNFSF9,KTN1,ZNF385B,CDS1,UHRF1BP1L,RNF220,SP100,DACT1,ACSL4,ARL4D,CDKN2D,SCN3A,RNF169,ENPP4,CAMSAP3,SSH3,LGALS8,FZD4,NRBF2,SYNE2,CDCA2,NUSAP1,PEX5,STX10,TTC12,SLC9A6,SIPA1L1,WWTR1,INPP4B,PLEKHG1,PDXK,GEN1,FARP1,TAOK2,TNRC6C,RBM24,PARP14,MAN1A2,PDIA3,GMCL1,ANO9,PKN1,GSTP1,ARHGEF40,ETS1,KCNC4,TSPAN17,SRPX2,TIPRL,ICAM1,NEO1,PDIA4,DTX3L,CXCL16,ANK1,ADD3,IRAK1,SLC27A6,ANKS1B,FAM160A2,ARSG,CTSC,MCF2L,PLEKHF1,ADAM15,MAPK11,AK3,ITM2C,TPCN1,S100A6,HCN3,AMOTL2,POU6F1,CTNNAL1,FMN1,BCL9,RAPGEF2,MFSD2B,ELOVL3,PLEKHA7,BLVRA,FAM109A,SNTB1,SKA1,CRISPLD2,ABLIM2,TXK,PITX2,GALNT3,KIAA0141,ATXN7L3,ACVRL1,NR1D2,CCDC6,ARFGAP3,CENPE,NUP37,DCBLD1,CYBRD1,UNKL,TRIM2,AGRN,FAM199X,EPHA4,CUL4B,FHDC1,NDC80,MCCC1,TP53I11,HDAC6,NUP62CL,SDC1,CNTRL,SHC3,MKRN3,DDHD2,ANO4,TLN2,MYBL1,TRAM1,NEB,DDX59,ZNF462,PCGF5,MCTP1,ING1,CD55,EZR,ERP44,ESYT1,PRKRA,ANLN,FAM212B,IDH1,CLCN2,ZBTB7B,RHEB,VCP,PLEKHB1,IRX3,OPTN,DPYSL3,PLCH1,MFAP3L,TBC1D17,CDCA4,MAP2,P4HA2,DOLPP1,RAB11FIP1,CTNND1,PIK3C2B,TTC9,EPB41L4A,POMT1,PRKAA2,UBASH3B,ZCCHC24,CNTNAP2,DOCK11,IL18R1,PGAP1,SSX2IP,CORO1B,BMP2,RB1,DAZAP1,VASP,IGF1R,SPIN4,EXOC8,MDFIC,PLCB2,ALDH3A2,ABCC1,CHSY3,CYP26B1,WDR72,TESK1,CORO2A,SPATA13,KBTBD8,EIF2AK1,UNC45B,ANKRD29,ZDHHC3,G2E3,EPN3,MOSPD3,DHDH,MAPKAPK2,COQ10A,CSF1,MFSD2A,ITGA7,LTBP2,IFI6,CTBP1,RNF146,FAM45A,AVPI1,KCNAB3,NF2,UPF3B,FOXM1,XYLT1,DGKA,ERBB2,RASGRP3,CCNL1,SLC7A2,LPIN3,C1orf116,CYP26A1,PER2,RAD23A,CDK14,EFR3A,N4BP3,PLCG2,GYS1,SCN2A,FAR1,CTH,CPD,SIRT1,MBP,FIGNL1,CDC20,DNAJC10,DUOX1,ATP1A1,RTN4RL1,PTK7,PSMD3,ADAMTS14,C1orf43,RPL22,LTA4H,AIFM3,ZNF701,NDST3,CMTM4,MAN2B2,GOLIM4,TRAPPC10,CD63,MACC1,RUSC2,GABRG2,PSMD10,NKRF,JAG2,DSE,PPP2R3A,SLC9A2,SIRPA,GBX2,CEP97,MAGEE1,BUB1,KLF9,SLC45A3,CAMK2G,TLE6,IGDCC4,DLGAP1,HMMR,MLEC,PSMB4,NR3C1,AMFR,PPARA,AKAP3,PELI3,FXR2,FNDC3A,BCAR1,BSDC1,MAPK8IP1,CD83,SCRN2,TMEM50B,BANK1,SERPINA1,FAT4,TWSG1,ZMYND19,TMC5,NETO2,CLIP4,FAM117A,PPP2R3C,PKD2,SPCS3,ACADM,TBC1D4,NDFIP1,DIS3L,GAA,ACVR1,PPP4R4,TTC39B,ATP8A1,FAM129B,KLC2,PPFIBP2,GATA3,PLXNA1,PLA2G16,SLC20A1,ELMOD2,NCS1,CHST2,CTGF,ELMO2,ZFP36,RGS3,IQCE,IL31RA,AOX1,STEAP2,ATRNL1,IQCD,RCAN3,LAMP2,ORAI2,LOC81691,TMEM68,KIFC2,PBK,CASP9,HSPA12A,NBPF3,MGAM,TNS1,AURKB,MCFD2,SLC25A5,SPNS3,ULK2,ARHGEF26,SGPP1,SFXN1,HLF,SLC25A4,RBM47,PLK2,PTER,TBX1,GNPTAB,DHTKD1,TMEM8B,TANC2,UNC5B,TRAF5,RTN3,LZTS1,DLAT,DDX58,KLF2,MRPL44,CDK17,INPPL1,FRMD4A,HLA-E,CALB2,DGKQ,C6orf106,ISYNA1,NOTCH2,SLC1A3,BMP2K,KIAA1161,MECOM,ITGA3,PIK3AP1,BDH1,RUNDC3B,OPN3,SORL1,PIKFYVE,RIMS2,TSPAN33,EEF1D,FAM69A,IGSF3,EPB41L5,DDB2,PMPCB,QSOX1,FADS2,B3GNT7,KIAA1841,ZNF84,TBC1D8B,B9D2,MICB,AMER1,PTPRH,ANO6,KCTD20,VEZT,FAM133B,KDM3A,GLT8D2,STX3,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,SERTAD2,DCK,NAB2,TCEAL4,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,NRBP1,PKD1L2,FRMPD3,PLA2G4A,PLEKHG3,SLC2A4,CEP70,ARMCX3,TRIP10,TMEM217,S100A11,NLRX1,BROX,CAST,SUZ12,IQGAP1,RPS6KA1,IRX4,KCTD12,RNF182,CD274,AIFM2,MNS1,GNB2,TMPRSS4,CYHR1,APLP2,FAM46A,CDKN1B,TNPO2,CNNM4,DAB2IP,PHKA2,NR2C1,MYO5B,SLC5A11,SEC23A,TMEM43,CAPN6,TEP1,COX11,SLC11A2,PRKCQ,BCL7B,C15orf39,SP4,PRDM11,NIN,OSBPL2,EPHA10,FYN,ZNF641,JAK1,PPP2R5A,KIAA1804,STAT1,PPP1CB,SLC27A1,NRG1,KLF5,MLKL,NR3C2,ATMIN,DENND5B,OTUD5,MRPS9,WASF3,ARHGEF3,ANKRD13D,PCOLCE,SLC16A14,JRKL,ATP9A,ARL4C,CYB561,APOBEC3H,SEPP1,SPR,PNPLA5,TEAD3,SIX4,LGALS3BP,TMCC3,RND1,SNTA1,FAM111A,PHF7,OXCT1,PTEN,MGAT1,CENPJ,SGK3,PRC1,ATP8B1,SLC44A2,ERCC2,MAP3K7,CNPY3,GFI1,SPRY2,NCOA2,SMC4,PCCB,RASGRF1,CASK,SHMT1,ARAP2,ERMAP,TEF,MPP1,PARP4,FURIN,LRRC1,GPLD1,RGS9,NUCB1,CTNS,RCBTB2,AMMECR1,SERPINB5,CCDC69,PGM2L1,GRIN2D,ETAA1,SLC25A38,NCAPG2,ARSB,JARID2,ESYT2,EXPH5,LTBP1,CPT2,CAMKK1,FLYWCH2,TAF6L,KIF2C,DNER,CACNB4,KREMEN1,TMC1,DENND2D,SH3KBP1,CHPF,ARHGEF10L,C7orf49,LRRC6,GRHL1,ZCCHC12,DPYSL2,TSPAN6,IMPAD1,PHTF1,DLG1,CAPG,POF1B,ANKRD12,AKR1B1,RAB20,RP2,NFU1,ARNT2,MYH14,TECR,PTPRE,RASGRP1,OLFML2A,ATL1,TDP1,TRIM8,SOD1,RNF165,ROR1,PTGFRN,ADRBK2,STK17B,TCN2,EDNRA,CXXC4,ARHGEF19,NEIL1,FASTKD1,DHRS13,UEVLD,IARS2,ADIPOR1,APBA2,RAP1GAP,PSMC1,PPP2R5D,MIIP,STARD3NL,GRN,LRRFIP2,PEX6,ELOVL7,ASL,ATP6V1E2,SAMD9,PHLPP1,ZNF432,LRRN2,KCNN4,EBF4,FNIP1,KNTC1,RFX5,ACAD8,NCEH1,LRIF1,HP1BP3,PARD3B,GYLTL1B,AMDHD1,EGFR,MUM1L1,GLCE,GNAS,BCAR3,XKRX,NUDT16,TSC1,SLC6A6,UTP14C,CGREF1,NFKBIA,ALPK3,RHOBTB2,YOD1,PITPNA,EGFL7,KIF12,PROM2,SLC25A24,SLC2A8,PSME2,ABCG4,MORC4,GMPR,TDRKH,ZMYND10,MICALL2,ARHGEF16,SS18,KCTD15,SETDB2,KHNYN,ZDHHC12,FRYL,SMO,RPN2,STEAP3,GOT1,APIP,PDIA6,F2R,HSPA2,SCYL3,FRS3,SUSD3,MAP3K3,GCA,BAG4,TAF5,KREMEN2,OSTM1,ERBB2IP,DUSP4,DOCK5,MAP3K6,BFSP1,BHLHB9,PEX2,OVOL1,CANT1,AKNA,REEP4,LIFR,CBX4,SORT1,POC1B,FRMD6,LRP4,FAM134A,MIER3,NOTUM,TRMT2B,POMGNT1,ZNF212,IL17RB,IRF2BPL,MDM1,MLPH,KIAA0319,BRD7,TRIM3,IQGAP3,SUN2,ADAM17,RAB3B,GCLC,PHLDB3,ASPM,OGDHL,MBNL3,LRRC66,POLD3,SPAG1,MAP1B,HNRNPH2,DHRS2,TADA2B,OTUB2,GLB1,L1CAM,SNPH,ZNF596 |
| 1.327e-03 | -6.62 | MODULE_255 | MSigDB lists | MODULE_255 | 414 | 83 | 17758 | 2588 |
ACVR1,AASS,MRPS15,TP53,MAPK4,CCNL1,NANS,BAIAP3,CMTM6,C1orf116,CYP1A1,RNF220,METTL7A,PAQR5,ESPN,EPB41L4B,PDE4D,SCARA3,TUBA4A,ATG4D,TMCC2,TDP1,TCEB2,LAP3,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRIM7,KDM4D,AMZ2,PTGS2,PI4K2B,NEIL1,MPRIP,PLEKHG1,PPP1CB,RNASEL,RRAGD,LMTK3,CDH22,FAM169A,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,C9orf69,CDK16,TMEM62,CITED2,FAR2,FAIM,CNOT6L,ITM2C,EEF1D,MOB4,AMOTL2,HMGN5,TBC1D8B,FMN1,ADCK3,MICB,PIP4K2C,FURIN,BCL2L13,FOS,BSDC1,PTPRF,FUCA1,CD8A,TIMP3,CSF1,WDR19,S100A5,FGD6,NXPH4,MAL2,GEM,TMEM120A,C17orf75,PKIA |
| 1.340e-03 | -6.62 | GSE14308_TH2_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_TH2_VS_NATURAL_TREG_UP | 187 | 43 | 17758 | 2588 |
FOXM1,GCAT,TMEM41B,CIT,SOX9,EPS8,ERCC6L,PRKACA,KIAA1147,WEE1,MDM1,GALNS,ALDH1A3,PASK,SRR,TMEM143,FAM63A,GTF2F2,TRIM3,ECI2,PLEKHF1,MDFIC,STT3B,WBP4,SPRY2,CCDC88A,UPF3A,KRT80,ERLEC1,B9D2,CCBL2,C18orf8,AHRR,HS6ST1,HAGHL,OTUB2,ARFGAP3,GRIN2D,PKD2,NFKBIZ,NDE1,APOL2,KDELC2 |
| 1.340e-03 | -6.62 | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP | 187 | 43 | 17758 | 2588 |
CCNC,FBLIM1,EPAS1,GNPDA1,TMTC3,CAMKK1,RASA2,HABP4,SLC36A4,FAM78A,TRAPPC8,SYTL4,SEPP1,DHRS3,SNX9,IFT27,RDH14,FUT1,CTSD,FAM134C,SULF2,SOCS5,SUN2,TRIM8,LONRF3,MPP1,ACBD3,EIF5A2,BTBD19,PRICKLE1,DNAJB14,PRKRA,PDIK1L,DCAF10,NCOA3,MID1IP1,HPSE,COL13A1,ZFP30,WWTR1,SERPINB6,FHL1,TOB1 |
| 1.340e-03 | -6.62 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | 187 | 43 | 17758 | 2588 |
WASF3,PLSCR4,NKX3-1,ST13,UGP2,IGFBP6,TMX4,MCOLN3,SOD2,C1orf198,DSE,DOCK11,PSIP1,SIRPA,IRF2BPL,CALD1,FRAS1,FAM13B,REEP1,SLC39A10,TIAM1,CPE,ATP2B1,SOCS5,REC8,EPB41L5,PDGFC,GCA,LGALS8,OSTM1,NFIB,FZD7,DPYSL3,ANKRD10,ZNF641,TIMP3,RAB11FIP2,CLIP4,PKD2,ARNT,TOB1,RNF146,PRKAR1A |
| 1.340e-03 | -6.62 | low_malignant_potential_(borderline)_tumour | COSMIC cancer mutations | low_malignant_potential_(borderline)_tumour | 41 | 14 | 17775 | 2585 |
GNAS,RB1,CTNNB1,JAK1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 1.341e-03 | -6.61 | FERM_3 | prosite domains | PS50057 | 48 | 16 | 11866 | 1802 |
FRMPD3,EPB41L5,FARP1,FRMD4A,NF2,FRMD6,EZR,FRMD4B,PLEKHH2,JAK1,EPB41L4B,EPB41L4A,TLN2,MYLIP,JAK3,FARP2 |
| 1.344e-03 | -6.61 | positive regulation of osteoblast proliferation | biological process | GO:0033690 | 10 | 6 | 16441 | 2455 |
BMP2,CTHRC1,ITGAV,SOX8,HPSE,CYR61 |
| 1.344e-03 | -6.61 | fibroblast migration | biological process | GO:0010761 | 10 | 6 | 16441 | 2455 |
TNS1,NOV,ILK,ZFAND5,SYNE2,SGPL1 |
| 1.344e-03 | -6.61 | regulation of microvillus organization | biological process | GO:0032530 | 10 | 6 | 16441 | 2455 |
ATP8B1,EZR,PLS1,KLF5,PLD1,RAP1GAP |
| 1.350e-03 | -6.61 | HUANG_DASATINIB_RESISTANCE_UP | MSigDB lists | HUANG_DASATINIB_RESISTANCE_UP | 78 | 22 | 17758 | 2588 |
PGM1,PDGFC,ELK3,IL15RA,AGPS,CAST,NDC80,BTN3A2,KCTD12,IFIT3,EGFR,SH3KBP1,RAC2,ZYX,ST5,POPDC3,CALD1,FXYD5,OSMR,DUSP10,F2RL1,SOCS5 |
| 1.354e-03 | -6.60 | GSE17721_LPS_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_6H_BMDM_UP | 198 | 45 | 17758 | 2588 |
ACVR1,HMGN3,NCKAP1,TNFSF9,CDK14,RCN1,ZFX,PCNA,PDCD10,CA2,FUT2,RABEP2,TIMP1,FICD,PHTF1,SLC46A1,RANBP1,CDKN1B,TRIM21,NFKB2,SNX10,RBMS2,PMPCB,CAPN6,FURIN,RAB3IP,RASA1,STX3,PTGS2,FYN,RBL1,RAP2C,MAP3K11,FAM110C,STK39,SH3BGRL2,SP6,ITGAV,IFIH1,SERPINB1,NRBP1,CPPED1,HOXC13,IRF1,USP43 |
| 1.355e-03 | -6.60 | regulation of neurogenesis | biological process | GO:0050767 | 620 | 120 | 16441 | 2455 |
EMX1,FOXO6,PAX6,NF2,SSH1,RET,EPHA4,TP53,GATA3,PLXNA1,CAMK1D,NCS1,GRM5,PER2,TP73,CTNNB1,CDKL5,DPYSL2,IL6ST,SMO,DNM2,BCL6,DUSP10,DAB2IP,DIXDC1,CTTN,NOTCH3,SEMA3G,PACSIN1,TIAM1,SEMA3B,SSH3,TIMP2,AKT1,CDC20,KLK6,CDK1,ULK2,RHEB,IRX3,DPYSL3,ARHGAP35,FYN,GPRC5B,BHLHB9,PTK7,LIMK1,PLK2,SIPA1L1,EFNA5,NRG1,RAB29,PLXND1,ITPKA,ARF6,RGS14,COBL,LZTS1,CTDSP1,GRN,BIN1,SEMA6B,SERPINE2,ADGRG1,CIT,LRP4,ETV5,SOX9,CRABP2,CALR,BMP2,SPP1,ITGA3,PTEN,GATA2,KIF13B,BMP7,MYCL,MEGF8,KNDC1,KIAA0319,PRKCI,SORL1,TNFRSF12A,NPTN,WNT3A,NTN1,GFI1,ITM2C,RIMS2,TLE6,CCDC88A,FAM134C,TGIF1,HES1,RHOA,MMD,ASPM,RAPGEF2,GRIN1,HMG20B,KIF20B,ILK,CDK5R1,MAP1B,PTPRF,CDK5RAP1,SEMA4D,TMEM30A,CSF1,GPER1,EFNA1,GDF11,SOX8,ARSB,SEMA3A,SHOX2,L1CAM,FOXA1,NGEF |
| 1.356e-03 | -6.60 | LENAOUR_DENDRITIC_CELL_MATURATION_UP | MSigDB lists | LENAOUR_DENDRITIC_CELL_MATURATION_UP | 113 | 29 | 17758 | 2588 |
QSOX1,MMD,AES,SLC11A2,GDF15,HMGN3,ATP1B1,CRABP2,TRIB2,OAT,DUSP5,LGALS3BP,CYB5A,ARF4,CD83,SPP1,CDH1,CTSC,CSF1,SPINT2,NR4A3,MAOA,PKD2,SERPINB6,CITED2,RAP1GAP,ACOT7,DUSP1,ABCG1 |
| 1.356e-03 | -6.60 | M_PHASE | MSigDB lists | M_PHASE | 113 | 29 | 17758 | 2588 |
PLK1,REC8,ZWINT,DLGAP5,CIT,NDC80,NUSAP1,KIF2C,PKMYT1,RAD17,ANLN,CDC25C,KIF11,NPM2,CCNA2,CDCA5,NEK2,AURKA,KIF22,BUB1,KPNA2,KNTC1,CENPE,UBE2C,HSPA2,MPHOSPH9,ESPL1,SMC4,RAD21 |
| 1.362e-03 | -6.60 | regulation of nervous system development | biological process | GO:0051960 | 709 | 135 | 16441 | 2455 |
EMX1,SSH1,AGRN,EPHA4,RET,GATA3,PLXNA1,CAMK1D,GRM5,NCS1,TP73,CTNNB1,CDKL5,IL6ST,DPYSL2,DLG1,DNM2,DUSP10,SEMA3G,CTTN,PACSIN1,TIAM1,KLK6,CDK1,RHEB,ULK2,IRX3,DPYSL3,GPRC5B,PLK2,LIMK1,TRAF3IP1,ITPKA,ARF6,LZTS1,GRN,SEMA6B,SERPINE2,SOX9,ETV5,BMP2,CALR,SPP1,ITGA3,GATA2,MEGF8,FLRT3,KIF13B,PRKCI,SORL1,TNFRSF12A,NPTN,NTN1,WNT3A,CCDC88A,GPR161,RIMS2,MMD,HMG20B,KIF20B,ILK,NPHP3,CDK5R1,PTPRF,SEMA4D,TMEM30A,CSF1,EFNA1,GDF11,SEMA3A,RARG,FOXO6,PAX6,NF2,TP53,PRKACA,PER2,KIF14,SMO,BCL6,DIXDC1,DAB2IP,NOTCH3,DVL2,SEMA3B,SSH3,TIMP2,AKT1,CDC20,CLSTN1,ARHGAP35,FYN,BHLHB9,PTK7,SIPA1L1,RAB29,NRG1,EFNA5,PLXND1,RGS14,COBL,CTDSP1,BIN1,WASF3,ADGRG1,CIT,LRP4,CRABP2,SRPX2,SIX4,ADGRB2,PTEN,MYCL,BMP7,KNDC1,KIAA0319,ITM2C,GFI1,TLE6,FAM134C,TGIF1,HES1,RHOA,RAPGEF2,ASPM,GRIN1,MAP1B,CDK5RAP1,GPER1,SOX8,ARSB,SHOX2,L1CAM,FOXA1,NGEF |
| 1.366e-03 | -6.60 | LEE_NEURAL_CREST_STEM_CELL_UP | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_UP | 139 | 34 | 17758 | 2588 |
GRN,SORBS1,S100A11,ZCCHC24,SERPINB9,CRABP2,PHLDA1,HOXB2,CYP26A1,NRP2,SPP1,CDH1,KCNK5,DACT1,MITF,RRBP1,TFAP2A,ERBB3,MOXD1,TRIM62,SCN3A,MDFI,ELK3,C3orf52,LITAF,ROR1,ALCAM,RHOB,EDNRA,PITX2,LDLRAP1,HMGA1,L1CAM,LZTS1 |
| 1.368e-03 | -6.59 | plasma membrane | cellular component | GO:0005886 | 4806 | 769 | 17570 | 2579 |
DOC2A,ADD1,GRIK2,SLC25A13,PNPLA2,RET,MCOLN3,CACNA2D2,NRG2,LYNX1,TGOLN2,SYTL4,MORF4L2,SNX9,GRM5,LYPD5,CALM2,ZYX,RGS12,TGFBR3,MUC4,CABP1,PPP1R16A,SLC46A1,ATP13A3,FUT1,DNM2,CLDN4,PIK3CD,PPP1CA,WBP4,TIAM1,CPE,IL10RB,PRKAR2B,F12,ARF4,LCP1,ABR,SLC44A3,PLCG1,ENPP1,GRID2IP,ATP7B,NOD2,RELL1,ARF6,HSPB1,SCN5A,ITGA6,RAB23,ZNRF3,FAM21C,MERTK,TTYH3,RAC2,CD22,FLRT3,PCYOX1,FAM84B,PANX2,CNGA1,NCAM1,DGKG,ULBP2,MYLIP,PAQR7,CALCRL,ILK,GNA11,RHOB,PTPRF,IL1R1,ETS2,SLC4A4,SEMA4D,RAET1L,OSMR,DYSF,OSCP1,STK39,MAL2,DRP2,ARPC2,TRPC3,RUSC1,TMEM173,DMPK,MTM1,GRHL2,CD82,ETNK1,RGS20,PKP2,IL13RA1,MGST2,MVB12B,PRKACA,APC2,TNFSF9,REPS1,KTN1,MUC16,SCNN1A,CDH1,ENPP5,TAX1BP3,RTKN2,ARL4D,LRP11,DLG3,RAB27B,SCN3A,ENPP4,COL6A2,FZD4,PLEKHO1,SYNE2,CYS1,SYP,RAB38,TANC1,XRCC6BP1,GABARAPL1,IRS2,ALDH3B1,SHROOM3,SLC9A6,CORO1C,AXL,SIPA1L1,TRABD2A,PRIMA1,RGS14,TTC8,TCAF1,FARP1,HSP90B1,MPZL1,BACE1,TRAF2,SDC4,FLOT1,BTN3A1,CTSZ,ANO9,NUCB2,PKN1,PLPPR4,KCNC4,TSPAN17,SRPX2,ICAM1,NEO1,CAPN2,DIRAS3,CXCL16,ANK1,PDCD10,ADD3,IGSF9,IRAK1,ITGB8,SLC27A6,ANKS1B,CALD1,MCF2L,KCNK5,GPC3,ADAM15,TMBIM6,WWP1,IGFBP2,SGCB,ITM2C,TPCN1,S100A6,HCN3,AMOTL2,PVRL4,PLSCR1,CTNNAL1,FMN1,RAPGEF2,PIK3R1,GRIN1,EMP3,SNTB1,TXK,CNTNAP1,PROM1,LDLRAP1,ACVRL1,RAB11FIP2,SYT7,ITGAV,FHL1,CD81,CYBRD1,BCAM,TNK1,ILDR1,AGRN,EPHA4,F11R,ITPR2,CDIPT,HDAC6,PDGFB,SDC1,SPTB,SLC9A3R2,SUSD2,CPNE2,INPP5E,TM9SF2,CTNNB1,NPNT,SHC3,P4HB,IL6ST,SLC44A1,ABCA2,TNFRSF18,RGS5,NTN4,TLN2,ANO4,SMAGP,CD55,KCNIP3,MARK1,CELSR2,HN1L,CR2,EZR,NKAIN1,ESYT1,CLCN2,PLCH1,MFAP3L,HS6ST1,KCNMB4,PRKCDBP,ARRDC1,CTNND1,PIK3C2B,PIEZO1,TC2N,PRSS8,BMF,USH1C,LGALS3,RASA2,FXYD3,HLA-F,SLC22A31,RACGAP1,CNTNAP2,NCKAP1,DHRS3,IL18R1,ANO1,CORO1B,B4GALNT1,BMP2,VASP,IGF1R,FRAS1,ICAM5,TBCD,PAK2,FCHO1,EXOC8,SELK,PIM1,TMEM8A,WNT3A,MPHOSPH9,CKAP4,ABCC1,PCDH1,RGMB,SPATA13,SCRIB,PRX,CDK5R1,NMT2,RASGRP2,EPN3,COL13A1,PVRL2,MFSD2A,PHLPP2,ITGA7,CSF1,SLC2A6,PLD1,ATP1B3,CDAN1,IFI6,NIPA1,KCNAB3,NF2,DGKA,P2RX7,ERBB2,RASGRP3,SLC7A2,EMP2,PRR7,BCAP31,SDF4,SYTL2,CDK14,EFR3A,PLCG2,SRR,CDH3,OAS3,NOTCH3,SCN2A,GM2A,DVL2,SULF2,CLCN3,EVA1A,MBP,AKT1,PTGER4,DAG1,ATP13A2,PTGS2,DUOX1,ATP1A1,RTN4RL1,IDE,PTPRJ,ABHD12,PTK7,MMP17,CHMP4B,EFNA5,SYT13,BIN1,PACSIN2,CDH22,CD63,ADGRG1,TAB3,CTSB,BLVRB,GNAL,ERCC6L,SELL,GABRG2,JAG2,AIP,FZD6,IL22RA1,PARM1,SLC9A2,SIRPA,NRP2,M6PR,ZDHHC21,CD109,CDK16,ALPP,MAGEE1,SGK1,IL17RA,TSPAN13,KLF9,SYK,CAMK2G,ATP2B1,IGDCC4,DLGAP1,HMMR,P2RX4,RHOA,IFITM3,CRB3,PLAUR,LITAF,CAPNS1,BCAR1,RNPEP,BBS2,DGKE,CD83,BCL10,USP6,TMEM50B,FAT4,ZMYND19,NETO2,PKD2,ICOSLG,ZBTB33,ARHGEF4,DIS3L,LAMP1,ACVR1,HSPG2,SSH1,LGR4,VANGL1,ATP8A1,FAM129B,PLXNA1,PJA2,SLC20A1,NCS1,PICK1,CTGF,STIM1,RGS3,OSBPL3,IL31RA,STEAP2,PIK3CA,KCNS3,TACSTD2,HYLS1,PACSIN1,XKR8,METAP2,LAMP2,SGCE,ACVR1C,SNTB2,MGAM,SLC17A5,SLC25A5,RAB2B,SLC25A4,NKD1,TMEM8B,SPRY4,UNC5B,TRAF5,F2RL1,SLC31A2,LZTS1,DDX58,SEMA6B,INPPL1,HLA-E,DGKQ,PRKAA1,NOTCH2,SLC1A3,APBA1,TSPAN7,MESDC2,CALR,ITGA3,RALGPS2,PIK3AP1,SNX18,ZNRF2,LYPD3,VASN,SLC16A6,PRKG1,OPN3,DAPK1,SORL1,CD70,TNFRSF12A,CACNA1D,SYTL3,GPR161,RIMS2,TSPAN33,TRAK2,EPB41L5,FADS2,KCNJ12,MFI2,MMD,CEP89,MICB,PTPRH,CALM1,AMER1,DCHS1,ANO6,PYGL,VEZT,EPHA1,ATP8B3,PKM,ANTXR1,STX3,RASA1,FAS,DGKH,MMP15,SLCO4A1,GABRD,PLEKHH2,TJP3,ZDHHC20,MPP2,SLC4A3,ARAP1,PCDH19,EFNA1,EHD1,SPRED1,SLC2A4,TCTN2,TRIP10,ST14,CERCAM,IQGAP1,NDRG1,ATP2C2,KCTD12,CD274,DDR1,FLT3,GNB2,EPS8L2,EPM2A,CD46,APLP2,RALB,CNNM4,DAB2IP,EPHB4,PDE4D,TSPAN1,PHKA2,OSBPL7,FLOT2,TBC1D10B,SLC5A11,DMTN,UTRN,CLSTN1,PRKCQ,SLC11A2,ATP1B1,ITPR3,CBL,ALCAM,ATP10D,FZD7,EPHA10,FYN,JAK1,STK26,TSPAN18,SLC27A1,RAB29,NRG1,KLF5,HS3ST3B1,MLKL,COBL,PRKAR1A,PLSCR4,ANKRD13D,SLC16A14,SLC41A1,ATP9A,EPS8,ARL4C,PLD2,SLC35G2,EFNB1,ADGRB2,HLA-A,RND1,SNTA1,GNB5,PTEN,PRC1,CD9,SLC44A2,ATP8B1,ERBB3,MAP3K7,SPRY2,SLC16A5,MSH6,RASGRF1,PDGFC,CASK,ARHGEF28,ERMAP,MPP1,VAMP3,FURIN,UBAC1,YES1,AIF1L,CPTP,RGS9,CTNS,FGFR2,ABCB1,RYK,GRIN2D,GPER1,FZD5,OCLN,MELK,DEF6,ESYT2,RGMA,CASP3,MPP5,CACNB4,SLC8B1,DNER,TMC1,SH3KBP1,HTR1D,ABCD4,NKAIN3,EPCAM,RAB15,CDKL5,TSPAN6,DLG1,TRPC1,RAB20,RP2,CTTN,SLC39A10,PTPRE,MYRIP,IL1RAP,RASGRP1,TDP1,SOD1,ITCH,ROR1,STK17B,EDNRA,GPRC5B,KCNK1,MADD,ADIPOR1,APBA2,CPPED1,CAPN1,CD99,ARAP3,SERPINE2,BVES,ABCG2,CALM3,TEC,PHLPP1,QSOX2,NOXA1,CA2,KCNN4,OCRL,COL6A1,PRKCI,FXYD5,KNTC1,NPTN,HLA-C,C10orf54,GAD1,SLC12A2,CCDC88A,PODXL2,SPA17,BTN3A2,NUBP1,STEAP1,EGFR,GNAS,XKRX,TSC1,INSR,SLC6A6,UAP1,PLPP3,TMEM30A,CDCA5,NFKBIA,RHOBTB2,SHROOM2,JAK3,PROM2,DRD1,SORBS1,IL15,SLC2A8,HDAC11,ABCG4,MRAS,IL27RA,MICALL2,LRRC45,KIF14,SMO,STEAP3,ECE1,F2R,PDIA6,HSPA2,UPF3A,FRS3,CHP1,SEPHS1,SUSD3,GCA,BAG4,KREMEN2,PTPRU,SLC39A8,IGSF8,ERBB2IP,CD40,JADE1,BFSP1,SECTM1,SPTBN5,PLXND1,ABCA1,LIFR,ANXA3,SORT1,ENO2,TSPAN15,FRMD6,ARHGEF7,SH3D19,LRP4,TGFBR1,ITGA2B,XPR1,IL17RB,ADRBK1,ADORA1,LLGL2,KIAA0319,ARVCF,IQGAP3,SLC35A1,SYPL1,RAB3B,ADAM17,LEPR,MAP1B,HLA-B,CD8A,SWAP70,TRIM69,PRCP,CTSV,RAP2C,ARRB1,GEM,ATP6V1C1,L1CAM,CD33,ABCG1 |
| 1.368e-03 | -6.59 | KAMMINGA_EZH2_TARGETS | MSigDB lists | KAMMINGA_EZH2_TARGETS | 41 | 14 | 17758 | 2588 |
TOP2A,PCNA,RBL1,CDCA5,PRC1,NEK2,AURKA,NUSAP1,KPNA2,AHCY,AURKB,CCNB2,SMC4,PRIM1 |
| 1.377e-03 | -6.59 | ZHANG_TLX_TARGETS_DN | MSigDB lists | ZHANG_TLX_TARGETS_DN | 108 | 28 | 17758 | 2588 |
TIMP2,SORBS1,S100A11,NR4A1,S100A4,SAT1,TAP1,TCN2,SIRPA,GABARAPL1,PDGFA,BTG1,SCARB2,CSF1,BAX,AOX1,OPN3,PLEKHF1,TAX1BP3,NFKB2,CITED2,APBA2,PTPRE,TOB1,TTLL1,CPPED1,EPHX1,IGDCC4 |
| 1.379e-03 | -6.59 | POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 83 | 23 | 17758 | 2588 |
SOD1,TAOK2,TRAF2,ERBB2,STRADB,PKN1,MAP3K6,CARD10,EGFR,PICK1,CCND1,IRAK1,MADD,MAP3K11,MAP3K9,SERINC2,KIAA1804,MDFIC,MAP3K7,MAP3K5,CD81,CCDC88A,MDFI |
| 1.379e-03 | -6.59 | HOEBEKE_LYMPHOID_STEM_CELL_DN | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_DN | 83 | 23 | 17758 | 2588 |
KLF2,TCF25,HSP90B1,ALDH6A1,SERPINE2,SLC39A8,RALBP1,ETV5,CTDSPL,FHL2,TNS1,RAB38,ATP1B1,NFIB,MECOM,PLS3,TAX1BP3,LIMCH1,HSPB1,TMEM14A,MAFF,S100A6,CKS2 |
| 1.384e-03 | -6.58 | neural crest cell development | biological process | GO:0014032 | 67 | 20 | 16441 | 2455 |
SEMA6B,HES1,ACVR1,RET,SOX9,EFNB1,FGF19,GBX2,EDNRA,PITX2,SEMA4D,CORO1C,TBX1,SMO,TWIST1,NRG1,SEMA3G,SOX8,SEMA3A,SEMA3B |
| 1.388e-03 | -6.58 | TAATGTG,MIR-323 | MSigDB lists | TAATGTG,MIR-323 | 155 | 37 | 17758 | 2588 |
PPP4R4,CPEB4,CUL1,EGR3,PJA2,QSOX2,NFAT5,FANCI,ZDHHC21,IRF2BPL,CCND1,RCN1,PDCD10,FAM20B,CDKN1B,ANO4,MYLIP,STK35,MAP3K3,CLCN3,TGIF1,CXorf57,WHSC1,MCFD2,BORA,RANBP9,ULK2,NFIX,SLC4A4,RAB11FIP2,CCDC6,NR4A3,DCUN1D1,PPP1CB,PITPNA,AKIP1,RPS6KA3 |
| 1.388e-03 | -6.58 | Fosphenytoin (Antiarrhythmic) Metabolism Pathway | SMPDB pathways | SMP00618 | 4 | 4 | 978 | 190 |
SNTA1,SCN5A,SNTB1,SNTB2 |
| 1.397e-03 | -6.57 | SANA_TNF_SIGNALING_DN | MSigDB lists | SANA_TNF_SIGNALING_DN | 88 | 24 | 17758 | 2588 |
NQO1,EPAS1,CTNNAL1,ITGA6,CRIP2,FHL2,CALCRL,KCTD12,CAPNS1,ARHGDIB,JAG2,FAM198B,LDB2,DDR1,ANTXR1,PCTP,PHLDA1,NFIB,GLCE,CTGF,CDCA7L,NTN4,ATP1B3,C1orf43 |
| 1.403e-03 | -6.57 | BASSO_CD40_SIGNALING_UP | MSigDB lists | BASSO_CD40_SIGNALING_UP | 98 | 26 | 17758 | 2588 |
HSP90B1,NFKBIE,TRIP10,HLA-F,TCFL5,TAP1,LITAF,CR2,SNN,CD40,LHFPL2,TNFSF9,ICAM1,CD83,IER3,MAPKAPK2,RAC2,KCNN4,NFKBIA,CAPG,STAT1,PIK3CD,NFKB2,ICOSLG,PTPRE,EHD1 |
| 1.403e-03 | -6.57 | CAHOY_ASTROCYTIC | MSigDB lists | CAHOY_ASTROCYTIC | 98 | 26 | 17758 | 2588 |
PAPSS2,LPGAT1,RASA2,PANK1,PPARA,RGS20,PLD2,MERTK,TNFRSF19,TTYH3,KIAA1161,CKAP5,BTG1,ATP1A1,GRHL1,CYP4F11,CORO1C,ELF5,SLC46A1,TMEM51,FGD6,SLC27A1,NCEH1,AIFM3,TTPA,DNAI1 |
| 1.404e-03 | -6.57 | DE_YY1_TARGETS_DN | MSigDB lists | DE_YY1_TARGETS_DN | 93 | 25 | 17758 | 2588 |
HSP90B1,EPAS1,TACC1,EPS8,PRKAA1,ERBB2IP,CCNL1,RAB6A,BARD1,CDK1,EGFR,RASA1,FAS,RB1,PTEN,RBL1,CALD1,ERAP1,OSMR,TAGLN2,ITGAV,MPHOSPH9,SRSF9,USP16,SOCS5 |
| 1.406e-03 | -6.57 | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 182 | 42 | 17758 | 2588 |
RECQL,CMAS,TXN,UGP2,ADD1,CAPN12,NLRX1,RPS6KA1,RAB6A,CPNE2,MGAT1,KCNN4,CAPG,CD9,RAB20,ETHE1,DLG3,ITM2C,C12orf75,IL10RB,FLOT2,NUP85,CAMK2G,S100A6,HPS3,PTPN18,ING1,PQLC3,GUSB,S100A4,EIF2AK1,POLD3,DHX32,DGKH,SFXN1,NGFRAP1,DBI,KIAA1804,FAM195A,SERPINB6,CEP41,CSRP2 |
| 1.411e-03 | -6.56 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | MSigDB lists | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | 50 | 16 | 17758 | 2588 |
SLC2A4,INPPL1,SORBS1,AKT1,RPS6KA1,PIK3R1,FLOT1,CBL,IRS2,RPS6KA2,PTEN,PIK3CA,SERPINB6,PIK3CD,FLOT2,RPS6KA3 |
| 1.412e-03 | -6.56 | PEX19 (peroxisomal biogenesis factor 19) | protein interactions | 5824 | 114 | 31 | 16036 | 2547 |
MYO5B,B3GALT6,SOAT1,FAF2,PSMB4,MOSPD2,ASPM,DSTN,F11R,POMGNT1,PNKD,C3orf33,EGFR,VCP,MYO5C,GLCE,ATP13A2,TMEM54,ABHD12,FAM20B,GSKIP,ABCD1,GLB1L2,IQGAP3,PXMP4,FAR2,HSPB1,PSMA5,MYO5A,CD33,EGLN1 |
| 1.423e-03 | -6.56 | lysosomal membrane | cellular component | GO:0005765 | 269 | 58 | 17570 | 2579 |
LAMP1,GAA,SORT1,CD63,SLC2A8,TMEM55B,FLOT1,GNB2,TMEM63A,ABCD4,M6PR,MARCH8,NAPG,PQLC2,AP1M2,ZNRF2,VASN,COL6A1,RDH14,DRAM1,ABCA2,SLC44A2,PLEKHF1,ECE1,MARCH2,TSPAN1,TMEM8A,ITM2C,TMEM9,TPCN1,TMBIM1,LAMP3,P2RX4,LAMP2,VPS11,EVA1A,MMD,IFITM3,OSTM1,LITAF,AP5M1,SLC11A2,SLC17A5,GNA11,RHEB,C18orf8,GPLD1,ATP13A2,SCARB2,ENPP1,HPSE,CTNS,WDR11,ARRB1,CTSA,PLD1,ATP6V1C1,STARD3NL |
| 1.423e-03 | -6.56 | lytic vacuole membrane | cellular component | GO:0098852 | 269 | 58 | 17570 | 2579 |
LAMP1,GAA,SORT1,CD63,SLC2A8,TMEM55B,FLOT1,GNB2,TMEM63A,ABCD4,M6PR,MARCH8,NAPG,PQLC2,AP1M2,ZNRF2,VASN,COL6A1,RDH14,DRAM1,ABCA2,SLC44A2,PLEKHF1,ECE1,MARCH2,TSPAN1,TMEM8A,ITM2C,TMEM9,TPCN1,TMBIM1,LAMP3,P2RX4,LAMP2,VPS11,EVA1A,MMD,IFITM3,OSTM1,LITAF,AP5M1,SLC11A2,SLC17A5,GNA11,RHEB,C18orf8,GPLD1,ATP13A2,SCARB2,ENPP1,HPSE,CTNS,WDR11,ARRB1,CTSA,PLD1,ATP6V1C1,STARD3NL |
| 1.424e-03 | -6.55 | GSE17721_0.5H_VS_4H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_4H_CPG_BMDM_UP | 193 | 44 | 17758 | 2588 |
SORT1,ADD1,PEX6,LFNG,BACE1,DGKA,GPR180,TGFBR1,CAMK1D,PHF7,GNB5,MAGEE1,HMGCL,STT3B,PPP1CA,TMEM37,TPCN1,PHKG2,MLEC,TEF,ITCH,CORO2A,CASP9,CDC20,PIP4K2C,UBAC1,AURKB,MCFD2,IDH1,NAAA,TIMM8A,PRCP,ITPR1,APPL2,ARRB1,ARRDC1,AURKA,EIF4EBP2,SSNA1,ALG2,PDXK,HMGA1,TMEM131,ABCG1 |
| 1.424e-03 | -6.55 | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN | MSigDB lists | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN | 193 | 44 | 17758 | 2588 |
ST13,RPS6KA1,SERPINB9,KCTD12,PSME1,PRKACA,FAM46C,B4GALNT1,CYP1A1,RGS3,ZFP36,PAK2,CD9,MDFIC,USP38,MYH14,CLIP2,GM2A,CRTAP,EPHX1,GUSB,NR4A1,LITAF,C1GALT1C1,COL7A1,SNX12,C3orf58,LCP1,MAPKAPK2,HLA-B,TAPBP,STAT6,ITGA7,NAB2,NMI,HDAC1,NR4A2,NRGN,JAK3,NDFIP1,PTGES,IRF1,FAM134B,XDH |
| 1.424e-03 | -6.55 | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | 193 | 44 | 17758 | 2588 |
LMO7,SPRED1,SSH1,FAM199X,DNAJB2,EPHX4,NDRG2,B4GALT4,NUCB2,DHRS3,PDGFB,NFAT5,HLA-A,SLC25A36,GNS,MGAT1,SNX18,SLC44A1,SGK1,PIM1,LGMN,DLG3,LRP11,IL10RB,TIAM1,CASD1,MPP1,DNAJB14,MEST,ARF4,RHOB,GPLD1,MAGED2,MMP15,AGPAT2,UAP1,NFKBIA,INPP4B,EFNA5,ICOSLG,PER3,CBX7,TOB1,JARID2 |
| 1.426e-03 | -6.55 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | MSigDB lists | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | 17 | 8 | 17758 | 2588 |
MAPKAPK2,IRAK1,RIPK2,TAB3,MAPKAPK3,NOD2,MAPK11,MAP3K7 |
| 1.426e-03 | -6.55 | MODULE_474 | MSigDB lists | MODULE_474 | 17 | 8 | 17758 | 2588 |
LTBP1,QSOX1,NOV,CTGF,IGFBP6,CYR61,IGFBP2,SOCS3 |
| 1.426e-03 | -6.55 | MODULE_492 | MSigDB lists | MODULE_492 | 17 | 8 | 17758 | 2588 |
FUCA1,HEXB,ASAH1,CTSA,GLB1,GLA,ATP6V1C1,NAGA |
| 1.426e-03 | -6.55 | POSITIVE_REGULATION_OF_JNK_ACTIVITY | MSigDB lists | POSITIVE_REGULATION_OF_JNK_ACTIVITY | 17 | 8 | 17758 | 2588 |
KIAA1804,MAP3K11,MAP3K9,MDFIC,PKN1,MAP3K5,MAP3K6,MDFI |
| 1.428e-03 | -6.55 | growth cone | cellular component | GO:0030426 | 128 | 32 | 17570 | 2579 |
ARHGEF7,IQGAP1,EPS8,EPHA4,CALM3,NDRG2,CALM2,ITGA3,SNX18,CDKL5,FLRT3,DPYSL2,EXOC8,DNM2,MYH14,CTTN,DLG3,MYO5A,RASGRF1,ORAI2,TIMP2,CALM1,STMN3,KIF20B,CDK5R1,STX3,DPYSL3,TSC1,TMOD2,L1CAM,COBL,NGEF |
| 1.439e-03 | -6.54 | regulation of protein binding | biological process | GO:0043393 | 157 | 38 | 16441 | 2455 |
CTHRC1,NKX3-1,ADD1,LFNG,ARHGEF7,TRAF2,FLOT1,NES,TGFBR1,AES,PRKACA,PDGFB,CTNNBIP1,BMP2,APLP2,TGFBR3,RALB,BAX,ADAM15,TMBIM6,SORL1,DAB2IP,IFIT1,WNT3A,PLK1,EPB41L5,RAPGEF2,AMFR,PPARA,AURKB,PTPRF,LDLRAP1,PLK2,ARRB1,AURKA,NRG1,PLXND1,TMEM173 |
| 1.439e-03 | -6.54 | energy reserve metabolic process | biological process | GO:0006112 | 157 | 38 | 16441 | 2455 |
PRKAA2,ACACB,GAA,PPP1R2,UGP2,IQGAP1,CACNA2D2,CALM3,ITPR2,PRKACA,GNB2,EPM2A,PER2,CALM2,IL6ST,KCNS3,GYS1,CACNA1D,PPP1CA,PHKA2,PHKG2,GFPT1,PGM1,AKT1,CALM1,PYGL,PRKAR2B,ITPR3,SLC25A5,LEPR,GNAS,PRKAG2,SLC25A4,ITPR1,PGM2L1,PPP1CB,PPP2R5D,PRKAR1A |
| 1.439e-03 | -6.54 | regulation of establishment of protein localization to plasma membrane | biological process | GO:0090003 | 49 | 16 | 16441 | 2455 |
SORBS1,AKT1,PIK3R1,EZR,PLS1,BCL2L1,ARHGEF16,KIF5B,LDLRAP1,PPP2R5A,ITGA3,PRKCI,DLG1,GPER1,ARF6,TMBIM1 |
| 1.443e-03 | -6.54 | response to nitrogen compound | biological process | GO:1901698 | 987 | 181 | 16441 | 2455 |
CASP3,SSH1,NRG2,PSME1,ITPR2,PDGFB,SDC1,SPTB,TP73,CALM2,SESN3,PSMD1,CTNNB1,CTGF,SHC3,DPYSL2,PSMC2,KLF3,FOSB,PIK3CA,DNM2,AKR1B1,RASGRP1,SOD1,ACVR1C,EZR,AGO4,PRKAR2B,PRKRA,POR,RHEB,ENPP1,AREG,NOD2,CAB39,EIF4EBP2,PSMC1,GAB1,RRAGD,DDX58,PRKAA2,KLF2,INPPL1,RASA2,DGKQ,SOX9,PRKAA1,PSMD7,ATP6V1E2,CALM3,DUSP5,TIMP1,IGF1R,COL6A1,PRKCI,NCAM1,PSMA5,CALM1,STRADB,PSMA4,EGFR,RASA1,GNAS,IL1R1,TSC1,INSR,PRKAG2,NFKBIA,SH3BP4,RAB31,NR4A2,MAP3K5,TRPC3,JAK3,COL16A1,TMEM173,DRD1,EGLN1,SPRED1,SORBS1,SLC2A4,FOXM1,SLC2A8,PSME2,WDTC1,ERBB2,P2RX7,RASGRP3,BCL2L1,PRKACA,GNB2,PDGFA,CCND1,ATP6V0B,CCNA2,CDH1,RALB,SRR,CDKN1B,DAB2IP,GOT1,PDE4D,IFIT1,RASGEF1A,FRS3,SIRT1,RIPK2,AKT1,DMTN,PRKCQ,ERBB2IP,DAG1,CASP4,SOCS3,IRS2,DUOX1,PTGS2,FYN,IDE,JAK1,PSMD3,STAT1,SLC27A1,NRG1,SPTBN5,LTA4H,PRKAR1A,HSP90B1,SORT1,CPEB4,TRAF2,CTSB,GNAL,FLOT1,PSMD10,SELL,GABRG2,FGF19,ICAM1,HDAC9,CAPN2,IRAK1,PTEN,BMP7,BAX,TMBIM6,ERBB3,CAMK2G,MYO5A,GCNT1,DUSP1,HCN3,P2RX4,PDGFC,RASGRF1,ADAM17,RHOA,SHMT1,PSMB4,WNT10B,RAPGEF2,NR4A1,PIK3R1,GRIN1,PPARA,GGH,YES1,FOS,BCAR1,GPLD1,BTG1,MARC1,TIMP3,FGFR2,FGF18,NR4A3,GRIN2D,GPER1,ATP6V1C1,TBC1D4,CPEB2 |
| 1.446e-03 | -6.54 | cell redox homeostasis | biological process | GO:0045454 | 58 | 18 | 16441 | 2455 |
QSOX1,TXN,GCLC,TMX4,ERO1A,PDIA5,PDIA3,ERP44,TXNDC9,TXNDC11,QSOX2,PDIA4,PRDX4,DNAJC10,P4HB,AIFM3,PDIA6,TMX1 |
| 1.451e-03 | -6.54 | MODULE_493 | MSigDB lists | MODULE_493 | 64 | 19 | 17758 | 2588 |
LTBP1,C6orf1,TRIP10,EPHA4,CTDSPL,MYO5C,ST5,TIMP3,MITF,PPM1H,DRAM1,CNNM4,ARNT2,ZMIZ1,NDE1,MYLIP,CLIP2,AFAP1,SOCS5 |
| 1.452e-03 | -6.53 | peptidyl-serine phosphorylation | biological process | GO:0018105 | 121 | 31 | 16441 | 2455 |
PLK1,PRKAA2,PINK1,AKT1,MAPKAPK3,PRKAA1,TGFBR1,PDK3,AURKB,CCNB1,ILK,PRKACA,PDGFB,CDK1,CDK5R1,MAPKAPK2,RPS6KA2,ADRBK1,CSNK1G1,PAK2,SGK3,SGK1,AURKA,MAPK13,STK39,MAPK7,MAST4,SYK,HIPK3,DMPK,MAPK12 |
| 1.455e-03 | -6.53 | KEGG_CELL_ADHESION_MOLECULES_CAMS | MSigDB lists | KEGG_CELL_ADHESION_MOLECULES_CAMS | 129 | 32 | 17758 | 2588 |
CD99,MPZL1,HLA-F,HLA-E,ITGA6,SDC4,SELL,F11R,CNTNAP2,CD274,SDC1,ICAM1,HLA-A,NEO1,CDH1,ITGB8,CD22,CDH3,CLDN4,HLA-C,NCAM1,CD40,ALCAM,CNTNAP1,PTPRF,HLA-B,CD8A,PVRL2,ITGAV,ICOSLG,L1CAM,OCLN |
| 1.455e-03 | -6.53 | PID_PDGFRB_PATHWAY | MSigDB lists | PID_PDGFRB_PATHWAY | 129 | 32 | 17758 | 2588 |
PLA2G4A,IQGAP1,EPS8,NCKAP1,PDGFB,SLC9A3R2,PTEN,DNM2,PIK3CA,ACTA2,PIK3CD,CTTN,DOCK4,RHOA,PIK3R1,YES1,ELK1,CBL,CYFIP2,FOS,BCAR1,RASA1,ARHGAP35,PLCG1,PTPRJ,FYN,ARAP1,STAT1,ITGAV,ARPC2,GAB1,RPS6KA3 |
| 1.459e-03 | -6.53 | positive regulation of establishment of protein localization to plasma membrane | biological process | GO:0090004 | 32 | 12 | 16441 | 2455 |
KIF5B,SORBS1,ITGA3,AKT1,PIK3R1,DLG1,PRKCI,EZR,PLS1,GPER1,ARF6,ARHGEF16 |
| 1.470e-03 | -6.52 | negative regulation of cytoskeleton organization | biological process | GO:0051494 | 111 | 29 | 16441 | 2455 |
GAS2L1,ADD1,CKAP2,DMTN,EPS8,ARFGEF1,AURKB,CCNF,CCNB1,HDAC6,NUBP1,APC2,SPTB,PICK1,CORO1B,PLEKHH2,SWAP70,MID1IP1,TBCD,NEK2,TRIOBP,ARAP1,CAPG,AURKA,SPTBN5,TMOD2,TACSTD2,ESPN,SHROOM2 |
| 1.471e-03 | -6.52 | CYCLINS | prosite domains | PS00292 | 10 | 6 | 11866 | 1802 |
CCNE2,CCND1,CCNA2,CCNF,CCNB1,CCNB2 |
| 1.471e-03 | -6.52 | mitotic cytokinesis | biological process | GO:0000281 | 28 | 11 | 16441 | 2455 |
PLK1,KIF20A,SNX18,CKAP2,KIF23,NUSAP1,RACGAP1,CNTROB,ANLN,SNX9,RASA1 |
| 1.484e-03 | -6.51 | ruffle membrane | cellular component | GO:0032587 | 78 | 22 | 17570 | 2579 |
DDX58,EPB41L5,ADAM17,PACSIN2,RHOA,NF2,EPS8,SPATA13,EZR,AIF1L,EPS8L2,ARF4,LCP1,RASGRP2,PTPRJ,CDKL5,DNM2,SPRY4,ITGAV,PACSIN1,SPRY2,ARHGEF4 |
| 1.495e-03 | -6.51 | ST_P38_MAPK_PATHWAY | MSigDB lists | ST_P38_MAPK_PATHWAY | 37 | 13 | 17758 | 2588 |
MAPKAPK2,IL1R1,AKT1,DUSP10,MAPK11,MAPK13,MAP3K7,MAP3K5,ELK1,HSPB1,DUSP1,MAPK12,NR2C2 |
| 1.497e-03 | -6.50 | GSE3982_EOSINOPHIL_VS_TH2_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_TH2_DN | 188 | 43 | 17758 | 2588 |
CMAS,IL15RA,DHPS,VANGL1,PTTG1,PSMD7,IL27RA,GPSM2,DHRS3,C11orf95,ICAM1,APOBEC3B,CCNA2,TAF1B,DLG1,GOT1,MDFIC,NFU1,MANF,MINPP1,LMAN1,NR2C1,MPHOSPH9,NEK4,PLK1,MMD,PCBP3,PLEKHO1,SPA17,COX11,KIF20B,NUSAP1,PRRC1,PDHX,OPTN,DNAJC10,DCK,PRKCDBP,MDH1,NUP37,TBC1D4,LTA4H,ACOT7 |
| 1.497e-03 | -6.50 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP | 188 | 43 | 17758 | 2588 |
SORT1,PACSIN2,TXN,CEP70,NQO1,VANGL1,ERI2,ECI1,TSPAN7,KCTD9,PLS3,PLCG2,FBXO7,DAPK1,PLK4,TUBG1,BUB1,ALDH7A1,RNASEH2A,FAIM,RAG1,GFI1,KCTD3,TTLL1,SYK,ABCC1,WBP5,PCCB,TIMP2,HMGN5,CTNNAL1,MRPS18A,AURKB,EAF2,ALCAM,ADRBK2,SPAG1,RHEB,FECH,PEX5,ETS2,NEIL3,PSMC1 |
| 1.497e-03 | -6.50 | GSE7460_TCONV_VS_TREG_LN_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_UP | 188 | 43 | 17758 | 2588 |
LMTK3,EPAS1,IBTK,DAP,ELOVL7,MCTP2,FAM78A,SNN,DSE,SEPP1,FAM101B,DENND2D,KREMEN1,SH3KBP1,SPP1,TGFBR3,CYP2S1,LMO4,UBE2J1,DUSP10,IL17RA,TAGLN2,CNGA1,RAB27B,ALS2CL,SLC16A5,HP1BP3,PAQR7,SSH3,MBP,RGMB,ATP1B1,RASGRP2,XKRX,LDLRAP1,FAAH,TRIM69,ACVRL1,C1orf21,NR4A3,APPL2,HS3ST3B1,ST3GAL1 |
| 1.497e-03 | -6.50 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | 188 | 43 | 17758 | 2588 |
GALK1,AVPI1,KIAA1462,ENO2,HJURP,GCAT,NDRG1,C5orf30,GATA3,PKP2,FAM46C,TNFSF9,PPP2R3A,IER3,CAPN2,PFKL,PPME1,REEP1,AIM1,GYS1,EGLN3,FLOT2,SNX10,C9orf72,CTH,PGM1,IFITM3,GLO1,NPHP3,TP53INP2,FZD7,C18orf8,FRMD4B,NEIL1,HPSE,ACVRL1,H1F0,MFSD2A,P4HA2,UACA,TLE1,DMWD,MAMDC2 |
| 1.497e-03 | -6.50 | GSE3982_MAC_VS_TH1_UP | MSigDB lists | GSE3982_MAC_VS_TH1_UP | 188 | 43 | 17758 | 2588 |
SLC25A24,REPS2,TMX4,RGS20,ERI2,NDRG2,FTH1,PLXNA1,DPP8,BMP2K,MARCH8,SNX13,APLP2,DOPEY2,EFR3A,DACT1,RDH14,DRAM1,VAT1,TACSTD2,KLF9,ACOX2,TLN2,SPRY2,SOCS5,NAGPA,GCA,MMD,DENND1B,ACBD3,SAT1,RC3H2,CXorf57,SESN1,RHEB,ARHGAP24,SWAP70,CTNS,WWTR1,ARAP1,ZDHHC7,ITGAV,ANXA9 |
| 1.503e-03 | -6.50 | MODULE_317 | MSigDB lists | MODULE_317 | 404 | 81 | 17758 | 2588 |
ACVR1,AASS,MRPS15,TP53,MAPK4,CCNL1,NANS,BAIAP3,CMTM6,C1orf116,CYP1A1,RNF220,METTL7A,PAQR5,ESPN,EPB41L4B,PDE4D,SCARA3,TUBA4A,ATG4D,TMCC2,TDP1,TCEB2,LAP3,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRIM7,KDM4D,AMZ2,PTGS2,PI4K2B,NEIL1,MPRIP,PLEKHG1,RNASEL,RRAGD,LMTK3,CDH22,FAM169A,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,C9orf69,CDK16,TMEM62,CITED2,FAR2,FAIM,CNOT6L,ITM2C,EEF1D,MOB4,AMOTL2,HMGN5,TBC1D8B,FMN1,ADCK3,MICB,PIP4K2C,FURIN,BCL2L13,FOS,BSDC1,FUCA1,PTPRF,CD8A,CSF1,WDR19,S100A5,FGD6,NXPH4,MAL2,GEM,TMEM120A,C17orf75,PKIA |
| 1.503e-03 | -6.50 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | 161 | 38 | 17758 | 2588 |
TMEM184B,AGRN,CD63,INPP5D,STIL,MXD1,LMNA,PLS3,CCND1,RAC2,DAZAP1,CNTRL,CDK16,CALD1,OCRL,TNFRSF12A,KANK2,ALDH7A1,CTTN,S100A13,PPP6R1,CRTAP,AMOTL2,VAMP3,KIF1C,DAG1,NFIB,ULK2,FZD7,PLK2,WWTR1,FAM114A1,TCEAL4,SH3BP4,ITGAV,ARHGAP4,ZBTB33,DEF6 |
| 1.506e-03 | -6.50 | Glioma | KEGG pathways | hsa05214 | 65 | 20 | 6908 | 1076 |
AKT1,PIK3R1,CALM1,TP53,CALM3,PDGFB,EGFR,CALM2,CCND1,PDGFA,PLCG1,RB1,IGF1R,PTEN,SHC3,PLCG2,E2F1,PIK3CA,PIK3CD,CAMK2G |
| 1.506e-03 | -6.50 | Glioma | KEGG pathways | ko05214 | 65 | 20 | 6908 | 1076 |
AKT1,PIK3R1,CALM1,TP53,CALM3,PDGFB,EGFR,CALM2,CCND1,PDGFA,PLCG1,RB1,IGF1R,PTEN,SHC3,PLCG2,E2F1,PIK3CA,PIK3CD,CAMK2G |
| 1.507e-03 | -6.50 | cellular response to hormone stimulus | biological process | GO:0032870 | 687 | 131 | 16441 | 2455 |
UGT8,TRIM24,NRG2,PSME1,PDGFB,SPTB,CALM2,PSMD1,SHC3,PSMC2,FOSB,PIK3CA,RASGRP1,THRB,CASP9,PRKAR2B,POR,RHEB,ENPP1,CAB39,EIF4EBP2,ADIPOR1,PSMC1,GAB1,NR2C2,RRAGD,PRKAA2,RASA2,PRKAA1,PSMD7,ATP6V1E2,CALM3,DUSP5,TFAP4,IGF1R,PRKCI,NCAM1,PSMA5,PAQR7,CALM1,STRADB,ELK1,KDM3A,PSMA4,EGFR,RASA1,FECH,GNAS,TSC1,NCOA3,INSR,PRKAG2,RAB31,NR4A2,JAK3,RARG,DRD1,GAS2L1,SPRED1,SLC2A4,SORBS1,PSME2,SLC2A8,THRA,WDTC1,ERBB2,RASGRP3,PRKACA,GNB2,PDGFA,ATP6V0B,GOT1,DAB2IP,RASGEF1A,NR2C1,FRS3,AKT1,SOCS3,IRS2,FYN,IDE,ATP1A1,JAK1,PSMD3,STAT1,SLC27A1,NRG1,SPTBN5,NR3C2,PRKAR1A,NKX3-1,CTSB,SERPINB9,PSMD10,FGF19,HDAC9,BMP7,IGFBP2,ERBB3,KLF9,NCOA2,MYO5A,CAMK2G,DUSP1,RASGRF1,ADAM17,WNT10B,PSMB4,NR3C1,NR4A1,RAPGEF2,PIK3R1,PPARA,GRIN1,YES1,BBS2,BCAR1,FOS,GPLD1,CTSL,NR1D2,FGFR2,PLOD2,FGF18,NR4A3,GRIN2D,GPER1,PLOD3,ATP6V1C1,TBC1D4,CPEB2 |
| 1.518e-03 | -6.49 | pattern recognition receptor signaling pathway | biological process | GO:0002221 | 147 | 36 | 16441 | 2455 |
DDX58,UNC93B1,HSP90B1,TAB3,TRIM5,CTSB,RPS6KA1,CUL1,RPS6KA2,IRAK1,PIK3AP1,MAPK11,MAP3K7,SCARA3,NFKB2,LGMN,MAPK7,CNPY3,TNIP1,RIPK2,MAPKAPK3,ITCH,ELK1,DUSP4,FOS,BCL10,MAPKAPK2,CTSL,PELI2,NFKBIA,UBE2D2,NOD2,IRF7,IFIH1,PPP2R5D,RPS6KA3 |
| 1.519e-03 | -6.49 | liposarcoma | COSMIC cancer mutations | liposarcoma | 114 | 29 | 17775 | 2585 |
SPEF2,SMARCA2,ARAP3,HSP90B1,AKT1,GRIK2,GNE,TP53,ERBB2,VARS2,CBL,IDH1,PDXDC1,SPTB,EGFR,PDE11A,CORO1B,GNAS,RB1,SS18,CTNNB1,CDH1,HTT,PTEN,LLGL2,ATP7B,PLK4,PIK3CA,PER3 |
| 1.523e-03 | -6.49 | neuromuscular junction | cellular component | GO:0031594 | 50 | 16 | 17570 | 2579 |
SERPINE2,EPHA4,LRP4,UTRN,P2RX7,PRKCQ,COL4A5,KCNC4,PRKACA,CDK5R1,SNTA1,ITGA7,DLG1,NRG1,F2R,PRKAR1A |
| 1.524e-03 | -6.49 | KYNG_RESPONSE_TO_H2O2 | MSigDB lists | KYNG_RESPONSE_TO_H2O2 | 69 | 20 | 17758 | 2588 |
BAG4,CTSB,TAP1,PTGER4,GDF15,PLXNA1,COX6C,SEPP1,SLC20A1,CCNA2,TGFBR3,CTNNB1,CST3,PPP1CA,CD81,IL10RB,FLOT2,IFI6,PKIA,TUBA4A |
| 1.524e-03 | -6.49 | NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | MSigDB lists | NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | 69 | 20 | 17758 | 2588 |
HSP90B1,IL15RA,AKT1,IFITM3,CASP9,PPARA,TP53,IL18,PER2,FAS,PDGFA,HLA-B,CASP7,TGFBR3,TIMP3,STAT1,HLA-C,ETV4,RPGR,IRF1 |
| 1.527e-03 | -6.48 | HRAS (Harvey rat sarcoma viral oncogene homolog) | protein interactions | 3265 | 105 | 29 | 16036 | 2547 |
FAM213B,RASGRF1,PIK3R1,GRIN1,TP53,ERBB2IP,GPSM2,ICMT,CBL,CDC25C,PDGFB,SLC9A3R2,SH3KBP1,RASA1,RHEB,TP73,FYN,RGS12,INSR,FNTA,IRAK1,PRKCI,PIK3CA,GRIN2D,DAB2IP,PIK3CD,TIAM1,SPRY2,RASGRP1 |
| 1.529e-03 | -6.48 | KEGG_MAPK_SIGNALING_PATHWAY | MSigDB lists | KEGG_MAPK_SIGNALING_PATHWAY | 266 | 57 | 17758 | 2588 |
ELK4,PLA2G4A,CASP3,TAOK2,RPS6KA1,RASA2,TRAF2,CACNA2D2,TP53,RASGRP3,TGFBR1,MRAS,CACNB4,PDGFB,PRKACA,DUSP5,FGF19,MECOM,PDGFA,RAC2,RPS6KA2,PAK2,DUSP10,MAPK11,CACNA1D,MAP3K7,NFKB2,MAPK7,HSPA2,RASGRP1,DUSP1,MAP3K3,RASGRF1,AKT1,MAPKAPK3,NR4A1,RAPGEF2,DUSP4,ELK1,FOS,MAP3K6,EGFR,RASA1,MAPK8IP1,FAS,RASGRP2,MAPKAPK2,IL1R1,FGFR2,FGF18,MAP3K11,ARRB1,MAPK13,MAP3K5,HSPB1,RPS6KA3,MAPK12 |
| 1.534e-03 | -6.48 | - | gene3d domains | 3.80.20.20 | 7 | 5 | 9988 | 1574 |
ERBB2,INSR,ERBB3,IGF1R,EGFR |
| 1.535e-03 | -6.48 | positive regulation of cell projection organization | biological process | GO:0031346 | 271 | 59 | 16441 | 2455 |
GRN,FOXO6,AGRN,SERPINE2,ARHGEF7,EPHA4,RET,P2RX7,TGFBR1,NCKAP1,CAMK1D,CRABP2,MNS1,EPS8L2,CORO1B,RAC2,ITGA3,CDKL5,MEGF8,BMP7,PRKCI,DNM2,DAB2IP,ESPN,TNFRSF12A,NPTN,NTN1,WNT3A,PACSIN1,TIAM1,FAM134C,RIMS2,RHOA,RAPGEF2,PRKCQ,ILK,ARHGAP35,MAP1B,DPYSL3,FYN,GPRC5B,SEMA4D,HTT,BHLHB9,CORO1C,PTK7,LIMK1,TMEM30A,ARAP1,EFNA5,NRG1,ARPC2,ITPKA,ARSB,F2RL1,SHOX2,COBL,L1CAM,PROM2 |
| 1.535e-03 | -6.48 | PROTEIN_HOMODIMERIZATION_ACTIVITY | MSigDB lists | PROTEIN_HOMODIMERIZATION_ACTIVITY | 119 | 30 | 17758 | 2588 |
S100A11,HEXB,ABCG4,ABCG2,BNIP3L,CDA,CR2,EIF2AK1,BARD1,SLC9A7,FOXP2,TOP2A,CARD8,PVRL2,TBX1,CST3,PPP2R4,KIAA1804,MAP3K11,MAP3K9,BAX,MSH2,ANXA9,GLA,MAP3K5,NRBP1,S100A6,MSH6,CCDC88A,ABCG1 |
| 1.535e-03 | -6.48 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | 119 | 30 | 17758 | 2588 |
SNX8,GOLIM4,NQO1,LAP3,TBC1D1,SLC41A1,HLA-F,ARL4C,PPP1R14C,AIFM2,ETS1,PHLDA1,TP53I3,SH3KBP1,LMNA,MECOM,PDGFA,ARHGAP24,HLA-B,PPP4R1,ABCB1,TFAP2A,RAB31,SERPINI1,HLA-C,PDXK,MAP3K5,SERPINB1,ITM2C,PRKAR1A |
| 1.540e-03 | -6.48 | S_TK_X | smart domains | SM00133 | 55 | 18 | 9131 | 1455 |
AKT1,CIT,RPS6KA1,PRKCQ,GRK6,PKN1,PRKACA,ADRBK2,RPS6KA2,ADRBK1,STK38,PRKG1,SGK3,PRKCI,SGK1,MAST4,RPS6KA3,DMPK |
| 1.541e-03 | -6.48 | negative regulation of developmental process | biological process | GO:0051093 | 777 | 146 | 16441 | 2455 |
TSC22D3,EPHA4,GATA3,IL18,VASH1,FAM101B,TP73,CTNNB1,ELF5,DUSP10,TACSTD2,SEMA3G,ACVR1C,ASXL1,ARHGDIB,EAF2,SAV1,ULK2,ABR,IRX3,DPYSL3,ENPP1,AREG,PLK2,TBX1,HOXA9,TRAF3IP1,NKD1,HDAC1,ARF6,SEMA6B,UBASH3B,SOX9,FBLN1,BMP2,CALR,SPP1,TIMP1,GATA2,BHLHE41,VASN,FBXO7,SORL1,NTN1,WNT3A,GPR161,SOCS5,MFI2,NPHP3,NFIB,CDK5R1,GNAS,AP1AR,NCOA3,SEMA4D,NFKBIA,SFMBT1,EFNA1,GDF11,JAK3,SEMA3A,TOB1,RARG,XDH,IRF1,GAS2L1,PAX6,GRHL2,LFNG,FOXM1,INPP5D,SUZ12,TP53,ERBB2,PKP2,PRKACA,FLT3,CCND1,NOV,SMO,BCL6,CDKN1B,TNPO2,VAT1,CDH3,DAB2IP,DIXDC1,TWIST1,NOTCH3,LGMN,ETV4,SEMA3B,SIRT1,DMTN,FZD7,CORO1C,WWTR1,INPP4B,STAT1,NRG1,RAB29,ABCA1,CTDSP1,NKX3-1,SORT1,PINK1,ADGRG1,CIT,LRP4,TGFBR1,TRIB2,SIX4,ADGRB2,PDCD10,PTEN,BMP7,CST3,KIAA0319,MAPK11,TTPA,ITM2C,GFI1,TRIM62,HES1,RHOA,WNT10B,RAPGEF2,ASPM,PIK3R1,RGCC,MBNL3,PPARA,PRICKLE1,BBS2,ACVRL1,TWSG1,TBX18,E2F1,ITGAV,GPER1,OSR1,SOX8,NDFIP1,FOXA1,ABCG1,NGEF |
| 1.546e-03 | -6.47 | hair cycle process | biological process | GO:0022405 | 77 | 22 | 16441 | 2455 |
LGR4,SOX9,LRP4,TFAP2C,LDB2,SAV1,TNFRSF19,FZD6,EGFR,ZDHHC21,CD109,PDGFA,GNAS,CTNNB1,FGFR2,CTSV,DBI,SMO,HDAC1,CDH3,ERCC2,HOXC13 |
| 1.546e-03 | -6.47 | molting cycle process | biological process | GO:0022404 | 77 | 22 | 16441 | 2455 |
LGR4,SOX9,LRP4,TFAP2C,LDB2,SAV1,TNFRSF19,FZD6,EGFR,ZDHHC21,CD109,PDGFA,GNAS,CTNNB1,FGFR2,CTSV,DBI,SMO,HDAC1,CDH3,ERCC2,HOXC13 |
| 1.549e-03 | -6.47 | NEK4 (NIMA-related kinase 4) | protein interactions | 6787 | 16 | 8 | 16036 | 2547 |
HLA-B,HLA-E,PLAUR,DNAJB2,NRG1,HLA-C,CTDSP2,SDF4 |
| 1.549e-03 | -6.47 | MYO7A (myosin VIIA) | protein interactions | 4647 | 16 | 8 | 16036 | 2547 |
USH1C,CTNNB1,CDH1,MAP2,CALM1,VEZT,MYRIP,PRKAR1A |
| 1.549e-03 | -6.47 | GLB1 (galactosidase beta 1) | protein interactions | 2720 | 16 | 8 | 16036 | 2547 |
PLK1,CTNNBIP1,LGALS3,DNAJB2,CTSA,FBXO6,FOS,VCP |
| 1.554e-03 | -6.47 | intramolecular oxidoreductase activity | molecular function | GO:0016860 | 54 | 17 | 16491 | 2452 |
QSOX1,GNPDA1,ERO1A,TMX4,PDIA5,PDIA3,ERP44,ERP29,TXNDC11,QSOX2,ECI1,PDIA4,P4HB,ECI2,PDIA6,PTGES,TMX1 |
| 1.555e-03 | -6.47 | inositol lipid-mediated signaling | biological process | GO:0048017 | 142 | 35 | 16441 | 2455 |
TNRC6C,GATA3,NRG2,ERBB2,PLD2,PHLPP1,PDGFB,CA8,FGF19,NCS1,PDGFA,IGF1R,PTEN,PIK3CA,CDKN1B,PIK3CD,ERBB3,RHOA,AKT1,NR4A1,CASP9,PIK3R1,EZR,AGO4,EGFR,IRS2,PLCH1,FYN,FGFR2,PHLPP2,FGF18,PIK3C2B,NRG1,PLD1,GAB1 |
| 1.557e-03 | -6.46 | CSF1R (colony stimulating factor 1 receptor) | protein interactions | 1436 | 23 | 10 | 16036 | 2547 |
FYN,INPPL1,INPP5D,CSF1,PIK3R1,ITGAV,YES1,CBL,RASA1,SOCS3 |
| 1.558e-03 | -6.46 | LAU_APOPTOSIS_CDKN2A_UP | MSigDB lists | LAU_APOPTOSIS_CDKN2A_UP | 55 | 17 | 17758 | 2588 |
DAP,MYBL2,TP53,BCL2L1,TNFSF9,CARD10,RHOB,FAS,BCL10,PCNA,NFKBIA,PAK2,E2F1,CDKN1B,TNFRSF12A,TRAF5,RAD21 |
| 1.560e-03 | -6.46 | regulation of Wnt signaling pathway | biological process | GO:0030111 | 299 | 64 | 16441 | 2455 |
LGR4,PSME2,XIAP,PSME1,APC2,KREMEN1,CDK14,CCND1,PSMD1,RNF220,CTNNB1,DACT1,PSMC2,TAX1BP3,DAB2IP,DIXDC1,DVL2,SULF2,KREMEN2,ANKRD10,CXXC4,GPRC5B,ANKRD6,PSMD3,NKD1,WWTR1,TLE1,TRABD2A,CTNND1,PSMC1,CTHRC1,LRP4,SOX9,PSMD7,PSMD10,AES,ZNRF3,NOTUM,PPP2R3A,FZD6,HMGXB4,BMP2,CTNNBIP1,ITGA3,MDFIC,WNT3A,ZRANB1,PSMA5,MDFI,PSMB4,WNT10B,ASPM,AMER1,PRICKLE1,NPHP3,ILK,FOXL1,PSMA4,FGFR2,PLPP3,TBX18,LRRK1,FZD5,RNF146 |
| 1.568e-03 | -6.46 | PRKACA (protein kinase, cAMP-dependent, catalytic, alpha) | protein interactions | 5566 | 240 | 56 | 16036 | 2547 |
ADD1,TRIP10,NDRG1,IQGAP1,DCAF7,RASGRP3,ITPR2,SLC9A3R2,ITGA2B,TP73,CALR,CCND1,VASP,ADRBK1,NOXA1,PPP1R10,CDK16,CALD1,GYS1,IRF2,PDE4D,GAD1,APOBEC3G,NUP85,CCDC88A,ATP2B1,GPR161,MAP3K3,RASGRF1,KCNJ12,MBP,RHOA,GUSB,PFKFB2,NR3C1,DMTN,ITCH,PRKAR2B,FOS,RANBP9,LCP1,EGFR,NIN,SLC4A4,MAP2,ITPR1,HDAC1,AURKA,ARPC2,ITPKA,AKIP1,RGS14,RAP1GAP,ABCA1,PKIA,PRKAR1A |
| 1.568e-03 | -6.46 | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | 255 | 55 | 17758 | 2588 |
GRN,GAA,TRIM2,SERPINE2,S100A11,TBC1D1,DNAJB2,GATA3,NCKAP1,DUSP5,H1FX,MYO5C,IL17RB,ZYX,B3GALNT1,KIAA0895,TGFBR3,SRPX,IGF1R,ADRBK1,TIMP1,DPYSL2,RRBP1,CAPG,CD9,DNM2,RCAN3,EGLN3,ARL4D,MAST4,S100A13,GM2A,IGSF3,MX1,PTPN18,MGAT4B,SERTAD3,CR2,YES1,MEST,RHOB,ABR,FRMD4B,MAPKAPK2,NUCB1,TIMP3,FA2H,RIN3,SH3GLB2,TLE1,NRG1,IRF7,CABIN1,PLD1,CBX4 |
| 1.569e-03 | -6.46 | VERHAAK_GLIOBLASTOMA_CLASSICAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_CLASSICAL | 156 | 37 | 17758 | 2588 |
ARAP3,LFNG,SOX9,NES,TRIB2,TEAD3,MYO5C,SNTA1,PDGFA,RGS12,ITGB8,MEGF8,OSBPL3,SMO,ERCC2,EPHB4,CLIP2,SPRY2,RASGRP1,SSH3,ARAP2,HMG20B,ILK,DAG1,EGFR,FZD7,GNAS,IRS2,SLC4A4,C19orf66,ITGA7,SIPA1L1,DMWD,HS3ST3B1,PLIN3,SHOX2,PCSK5 |
| 1.570e-03 | -6.46 | SENESE_HDAC2_TARGETS_DN | MSigDB lists | SENESE_HDAC2_TARGETS_DN | 114 | 29 | 17758 | 2588 |
MYL9,UNKL,FADS2,BCAM,TRIM2,DEPDC1,IGFBP6,S100A4,ZCCHC24,MGAM,PKP2,NFIB,ALDH3B1,TNS3,SPP1,SESN3,TIMP3,DACT1,MATN2,SORL1,RTKN2,NTN4,ETAA1,TMEM37,NPTXR,SCARA3,LRP11,LOXL1,SEMA3B |
| 1.572e-03 | -6.46 | Cyclin_N | pfam domains | PF00134 | 32 | 12 | 16629 | 2504 |
CCNE2,CCNI,CCNC,CCND1,CCNA2,CCNB3,CCNO,CCNJL,CCNL1,CCNB1,CCNF,CCNB2 |
| 1.573e-03 | -6.45 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | 183 | 42 | 17758 | 2588 |
SUN1,LZTFL1,TSC22D3,PPFIBP2,KCTD12,SNN,TRIB2,DHRS3,LTBP3,RSAD1,SLC25A36,ADD3,A4GALT,DLG1,TRIM3,ZNF692,CRY2,KLF9,ECE1,PHKA2,MYLIP,DVL2,SMAGP,XKR8,DUSP1,ALDH2,ADCK3,LITAF,CLCN2,FOXL1,RASGRP2,DDAH1,TRAM2,SCARB2,FAAH,ANKRD6,TCEAL4,RYK,CSGALNACT1,HOOK1,CBX4,FAM134B |
| 1.573e-03 | -6.45 | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | 183 | 42 | 17758 | 2588 |
PARP12,FAM160B1,HERC5,FBXO6,PHLPP1,SNN,NTAN1,HERC6,MERTK,HMGXB4,CAPN2,NAPG,TNS3,FAM46A,IRAK1,ELMO2,RIMS3,OAS3,CLIP2,RNF169,CKAP4,MX1,VPS11,TRIM8,GUSB,PAPD7,LAP3,SLC11A2,KIF13A,IFIT3,C18orf8,MAN2A2,SCARB2,AREG,C19orf66,RIN3,CCDC69,FGD6,ZDHHC7,PITPNA,CMPK2,ZMIZ1 |
| 1.575e-03 | -6.45 | soft_tissue-fibrous_tissue_and_uncertain_origin-desmoplastic_small_round_cell_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-desmoplastic_small_round_cell_tumour | 33 | 12 | 17775 | 2585 |
SS18,CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,EGFR |
| 1.575e-03 | -6.45 | desmoplastic_small_round_cell_tumour | COSMIC cancer mutations | desmoplastic_small_round_cell_tumour | 33 | 12 | 17775 | 2585 |
SS18,CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,EGFR |
| 1.580e-03 | -6.45 | RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | MSigDB lists | RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | 74 | 21 | 17758 | 2588 |
CD55,TCF25,TRAPPC10,EZR,ASAH1,IL13RA1,NOTCH2,DUSP4,ITPR3,C15orf39,DUSP5,GABARAPL1,KLHL2,SWAP70,AREG,AIM1,ZNF165,NR4A2,KLF9,CHPT1,ABCA1 |
| 1.580e-03 | -6.45 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN | 74 | 21 | 17758 | 2588 |
CCNE2,CDA,AK4,AURKB,MGST2,CCNB1,CDK1,PDGFA,IRAK1,NOXA1,MTFMT,CDH1,NFKBIA,MAP3K9,CANT1,HDAC1,TNFRSF12A,IRF7,ERBB3,CCNB2,CTH |
| 1.587e-03 | -6.45 | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN | 194 | 44 | 17758 | 2588 |
GRN,LGALS3,S100A11,CTSB,HEXB,ASAH1,KCTD12,NOTCH2,SIRPA,ARHGEF10L,GNS,ATP6V0B,TNS3,TYMP,MGAT1,SLC16A6,PLCG2,CAPG,BCL6,DAPK1,ACSL4,NPTN,PTPRE,SNX10,SYK,CKAP4,GCA,TIMP2,PLSCR1,VAMP3,DIAPH2,NPC2,ILK,PCTP,FOS,ATP10D,CORO1C,NOD2,RAB31,GLB1,CTSA,ZMIZ1,SLC31A2,SLC27A3 |
| 1.587e-03 | -6.45 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | 194 | 44 | 17758 | 2588 |
PNISR,PARP12,TSC22D3,RET,NOTCH2,BAIAP3,PIGL,DDR1,TRIM68,FRY,CD22,AIM1,CAPG,SRR,PIK3CD,PDE4D,PIKFYVE,SNX10,GCNT1,MAP3K3,GCA,TGIF1,SYBU,CR2,PRKAR2B,CBL,CD83,RASGRP2,KLHL2,BTG1,FYN,BANK1,PTPRJ,ETS2,RIN3,DTX4,RAB11FIP1,CLMN,TTC9,TRAF5,TBC1D4,CBX7,OCLN,PHC1 |
| 1.591e-03 | -6.44 | KEGG_N_GLYCAN_BIOSYNTHESIS | MSigDB lists | KEGG_N_GLYCAN_BIOSYNTHESIS | 46 | 15 | 17758 | 2588 |
MAN2A2,DDOST,MGAT1,DOLPP1,ALG13,MAN1A2,MGAT4A,FUT8,MGAT4B,RPN2,ALG2,MGAT5B,STT3B,B4GALT3,MGAT5 |
| 1.591e-03 | -6.44 | STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | MSigDB lists | STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | 46 | 15 | 17758 | 2588 |
DDX58,MX1,DTX3L,HLA-B,SP100,STAT1,CD9,IRF7,TGFBR1,SAMD9,IFIT1,OAS3,HERC6,IFI6,DNAI1 |
| 1.591e-03 | -6.44 | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP | MSigDB lists | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP | 46 | 15 | 17758 | 2588 |
SUN1,ING1,EFR3A,HLA-F,RAB31,BCL6,EMP3,ARFRP1,EGR3,RAB6A,NPC2,NPTN,CDKN2D,DGKG,CTDSP2 |
| 1.595e-03 | -6.44 | MAP7D3 (MAP7 domain containing 3) | protein interactions | 79649 | 7 | 5 | 16036 | 2547 |
CBX5,SH3KBP1,VCP,SPINT2,TRAK2 |
| 1.595e-03 | -6.44 | C11orf65 (chromosome 11 open reading frame 65) | protein interactions | 160140 | 7 | 5 | 16036 | 2547 |
CALM2,CALM3,LASP1,UBE2T,CALM1 |
| 1.596e-03 | -6.44 | protein phosphatase binding | molecular function | GO:0019903 | 112 | 29 | 16491 | 2452 |
SOD1,HSP90B1,AKT1,TRAF2,IQGAP1,PIK3R1,TP53,STRN4,ERBB2,EGFR,VCP,SH3RF2,HSF4,IRS2,JAK1,CTNNB1,KCNN4,PPME1,STAT6,PPP2R4,NEK2,CDKN1B,CABIN1,DAB2IP,MAP3K5,DLG3,JAK3,PPP6R1,DRD1 |
| 1.603e-03 | -6.44 | ovary-low_malignant_potential_(borderline)_tumour-endometrioid | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-endometrioid | 21 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,IDH1,EGFR |
| 1.603e-03 | -6.44 | groin | COSMIC cancer mutations | groin | 21 | 9 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,IDH1,FLT3,GNA11,EGFR |
| 1.603e-03 | -6.44 | Merkel_cell_carcinoma | COSMIC cancer mutations | Merkel_cell_carcinoma | 21 | 9 | 17775 | 2585 |
RB1,NF2,CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,EGFR |
| 1.603e-03 | -6.44 | endometrioid | COSMIC cancer mutations | endometrioid | 21 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,IDH1,EGFR |
| 1.603e-03 | -6.44 | V$DR4_Q2 | MSigDB lists | V$DR4_Q2 | 244 | 53 | 17758 | 2588 |
CDK17,TM2D2,FAF2,FRMD4A,GRHL2,ENO2,PDGFRL,TGOLN2,CRABP2,PDGFB,GNB2,SPTB,TEAD3,PRRG4,SCML1,NKAIN3,FOXP2,APLP2,ADD3,PIK3AP1,TOX2,MITF,DUSP10,SGK1,TNFRSF12A,ERBB3,GAD1,TLE6,TRAK2,PODXL2,PHLDB3,LYRM1,RNF11,RGAG1,COX11,STRADB,C12orf65,ATP1B1,TP53INP2,EBF2,RASGRP2,OPTN,ARHGAP24,PGF,PTK7,NFKBIA,AMMECR1,NXPH4,NRG1,NDST3,ABCA1,JARID2,ABCG1 |
| 1.604e-03 | -6.44 | FRIDMAN_IMMORTALIZATION_DN | MSigDB lists | FRIDMAN_IMMORTALIZATION_DN | 33 | 12 | 17758 | 2588 |
RB1,CTGF,IGFBP6,ALDH1A3,TP53,HTATIP2,IRF7,MAP1LC3B,HSPA2,AHR,OPTN,CYP1B1 |
| 1.604e-03 | -6.44 | BURTON_ADIPOGENESIS_1 | MSigDB lists | BURTON_ADIPOGENESIS_1 | 33 | 12 | 17758 | 2588 |
IRS2,WEE1,CTGF,ETS2,ARL4C,LITAF,SGK1,NR4A2,PHLDA1,MAFF,RHOB,IER3 |
| 1.619e-03 | -6.43 | REACTOME_MITOTIC_M_M_G1_PHASES | MSigDB lists | REACTOME_MITOTIC_M_M_G1_PHASES | 167 | 39 | 17758 | 2588 |
SPC25,PSME2,CENPI,NDC80,ERCC6L,CDCA8,PSMD7,KIF23,PSMD10,PSME1,NUF2,KIF2C,CENPN,CKAP5,PSMD1,PSMC2,BUB1,KNTC1,NUP85,PSMA5,PLK1,CENPA,ZWINT,KIF20A,PSMB4,B9D2,CDC20,AURKB,SKA1,PSMA4,PRIM1,PPP2R5A,PSMD3,E2F1,NUP37,SGOL1,PSMC1,PPP2R5D,RAD21 |
| 1.624e-03 | -6.42 | Inflammatory mediator regulation of TRP channels | KEGG pathways | ko04750 | 98 | 27 | 6908 | 1076 |
PLA2G4A,CYP2J2,CALM1,PIK3R1,PTGER4,CALM3,PRKCQ,ITPR2,ITPR3,PRKACA,GNAS,IL1R1,CALM2,PLCG1,PLCG2,ITPR1,PIK3CA,PPP1CB,MAPK11,MAPK13,PPP1CA,PIK3CD,PLCB2,F2RL1,IL1RAP,CAMK2G,MAPK12 |
| 1.624e-03 | -6.42 | Inflammatory mediator regulation of TRP channels | KEGG pathways | hsa04750 | 98 | 27 | 6908 | 1076 |
PLA2G4A,CYP2J2,CALM1,PIK3R1,PTGER4,CALM3,PRKCQ,ITPR2,ITPR3,PRKACA,GNAS,IL1R1,CALM2,PLCG1,PLCG2,ITPR1,PIK3CA,PPP1CB,MAPK11,MAPK13,PPP1CA,PIK3CD,PLCB2,F2RL1,IL1RAP,CAMK2G,MAPK12 |
| 1.627e-03 | -6.42 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | 318 | 66 | 17758 | 2588 |
MORC4,COL18A1,BLCAP,PSME1,TEX2,OAT,MAP1LC3B,DDR1,CDK14,HSF2,FRYL,LMO4,CDH3,DIXDC1,CPD,GCA,CLCN3,CAPN6,COG2,PBK,SYNE2,RNF11,CDYL,ACO1,ERP44,PRKAR2B,NKAIN1,SESN1,DAG1,POR,AMZ2,POPDC3,ACYP1,SLC9A6,COBL,RRAGD,CDS2,LRRFIP2,GNE,ERI2,EFHD2,CYB561,SGPL1,FRY,SLC27A6,TBCD,TFAP2A,DAPK1,MYLIP,FAM69A,SUN2,CRIP2,FBXO9,BCL2L13,PTPRF,FAM64A,FGFR2,SPINT2,PPM1H,ARRB1,ACOT7,ARHGEF4,DOCK9,ABCG1,JARID2,KLF7 |
| 1.628e-03 | -6.42 | negative regulation of mitotic cell cycle phase transition | biological process | GO:1901991 | 158 | 38 | 16441 | 2455 |
PSME2,CTDSPL,PSMD7,TP53,PSMD10,PSME1,FANCI,IER3,TP73,CCND1,E2F7,RB1,CCNA2,PSMD1,PTEN,DACT1,PSMC2,FBXO7,BRD7,CDKN1B,BUB1,KANK2,CTDSP2,PSMA5,PLK1,PSMB4,CDC20,RGCC,PSMA4,CDK1,JADE1,PSMD3,PKD2,FHL1,UBE2C,MIIP,PSMC1,CTDSP1 |
| 1.628e-03 | -6.42 | CELL_DIVISION | MSigDB lists | CELL_DIVISION | 21 | 9 | 17758 | 2588 |
SEPT6,PRC1,DIAPH2,NUSAP1,RACGAP1,CNTROB,SEPT4,ANLN,RASA1 |
| 1.628e-03 | -6.42 | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | MSigDB lists | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | 21 | 9 | 17758 | 2588 |
MBP,TRIM2,FGFR2,SLC39A8,LHX6,TLE1,HMGN3,BCL2L1,FOXA1 |
| 1.628e-03 | -6.42 | ROY_WOUND_BLOOD_VESSEL_DN | MSigDB lists | ROY_WOUND_BLOOD_VESSEL_DN | 21 | 9 | 17758 | 2588 |
PROM1,SOX9,ATP8B1,FBXO9,KLF5,ATP1B1,ERBB3,EPB41L4B,C1orf116 |
| 1.631e-03 | -6.42 | nucleoside-triphosphatase regulator activity | molecular function | GO:0060589 | 312 | 66 | 16491 | 2452 |
ARHGAP11A,RALBP1,IQGAP1,ARFGEF1,RGS20,RASGRP3,ELMOD2,SIPA1L2,ACAP2,ARHGAP42,RGS12,RABEP2,SH3BP1,RGS3,RGS5,DAB2IP,RP2,TBC1D10B,DOCK4,ARHGDIB,ATP1B1,ABR,ARHGAP35,DNAJC10,PLEKHG6,TBC1D17,ARHGEF19,SIPA1L1,AGFG2,ARHGAP4,RGS14,RAP1GAP,STARD13,ARAP3,DEPDC1,TBC1D1,ARHGEF11,RASA2,RACGAP1,GPSM2,SYDE2,RINL,LLGL2,OCRL,RANBP1,FAM13B,TBCD,IQGAP3,ALS2CL,ARAP2,TBC1D8B,RAPGEF2,GRTP1,RASA1,RHPN1,ARHGAP24,RGS9,TSC1,RIN3,ARAP1,SH3BP4,ARRB1,ARFGAP3,ATP1B3,TBC1D4,CPEB2 |
| 1.633e-03 | -6.42 | human chr18p11.3 | chromosome location | human chr18p11.3 | 6 | 4 | 26250 | 2805 |
TGIF1,TWSG1,RALBP1,RAB31 |
| 1.637e-03 | -6.41 | Tetraspanin/Peripherin | interpro domains | IPR018499 | 33 | 12 | 18293 | 2672 |
CD63,TSPAN15,TSPAN6,CD82,TSPAN18,CD9,TSPAN13,TSPAN1,CD81,TSPAN7,TSPAN17,TSPAN33 |
| 1.643e-03 | -6.41 | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | 99 | 26 | 17758 | 2588 |
CCNC,GFPT1,CASP3,GAA,SORT1,TIMP2,HSP90B1,PPP1R2,MPZL1,NR4A1,NDRG1,F12,YES1,DUSP5,DNAJB9,PDIA4,APOBEC3B,DNAJC10,LDLRAP1,UAP1,ZFP36,UBE2J1,AHCY,FHL1,TRAM1,HSPB1 |
| 1.643e-03 | -6.41 | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | MSigDB lists | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | 99 | 26 | 17758 | 2588 |
KLF2,TSC22D3,PIK3R1,NES,ZFAND5,MYOM1,IRS2,SLCO4A1,DDAH1,INSR,TIMP3,CTGF,CYR61,AREG,RND3,METTL7A,KCNK1,CALD1,ZFP36,NFKBIA,BCL6,DIXDC1,KLF9,FHL1,TIPARP,DOCK9 |
| 1.648e-03 | -6.41 | regulation of generation of precursor metabolites and energy | biological process | GO:0043467 | 87 | 24 | 16441 | 2455 |
PRKAA2,PPIF,SORBS1,PINK1,RHOA,AKT1,PRKAA1,PPARA,TP53,P2RX7,PRKACA,VCP,IER3,IRS2,ENPP1,PRKAG2,INSR,PASK,PIK3CA,PRKCDBP,PPP1CB,PPP1CA,ARNT,PHKG2 |
| 1.649e-03 | -6.41 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043280 | 127 | 32 | 16441 | 2455 |
CASP3,NKX3-1,DAP,TRAF2,RET,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,BAX,DAPK1,CDKN1B,EGLN3,WNT3A,F2R,SIRT1,RHOA,ACVR1C,CASP9,SLC11A2,BCL2L13,VCP,BCL10,FAS,CASP7,NGFRAP1,ARRB1,GPER1,MAP3K5,XDH |
| 1.651e-03 | -6.41 | skin-malignant_melanoma-nodular | COSMIC cancer mutations | skin-malignant_melanoma-nodular | 29 | 11 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR |
| 1.651e-03 | -6.41 | pancreas-carcinoid-endocrine_tumour-insulinoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-insulinoma | 29 | 11 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 1.651e-03 | -6.41 | insulinoma | COSMIC cancer mutations | insulinoma | 29 | 11 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 1.652e-03 | -6.41 | KEGG_ENDOCYTOSIS | MSigDB lists | KEGG_ENDOCYTOSIS | 178 | 41 | 17758 | 2588 |
ARAP3,HLA-E,HLA-F,RET,PLD2,GRK6,SH3KBP1,HLA-A,ACAP2,IGF1R,ADRBK1,PRKCI,DNM2,WWP1,HLA-C,ERBB3,PIKFYVE,F2R,HSPA2,ARAP2,ITCH,VPS4B,CBL,ADRBK2,EGFR,EPN3,HLA-B,LDLRAP1,FGFR2,RAB11FIP2,DNM1L,ARAP1,SH3GLB2,RAB31,RAB11FIP1,ARRB1,ARFGAP3,CHMP4B,PLD1,ARF6,EHD1 |
| 1.653e-03 | -6.41 | NIELSEN_GIST | MSigDB lists | NIELSEN_GIST | 94 | 25 | 17758 | 2588 |
RFK,CTDSPL,CCDC68,PRKAR2B,PRKCQ,FOS,ANO1,DNAJB9,STK17A,WWP2,APLP2,PROM1,CA2,SLC4A4,MGAT4A,IMPAD1,ABCB1,ARRB1,KANK2,SPRY4,SLC12A2,BTBD3,CD81,CMTM4,CRTAP |
| 1.655e-03 | -6.40 | Tetraspanin_CS | interpro domains | IPR018503 | 21 | 9 | 18293 | 2672 |
CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN1,CD81,TSPAN17,TSPAN7 |
| 1.660e-03 | -6.40 | ovary-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-small_cell_carcinoma | 125 | 31 | 17775 | 2585 |
NF2,AKT1,ASXL1,AMER1,RET,PIK3R1,TP53,GATA3,ERBB2,NOTCH2,CBL,IDH1,FLT3,GNA11,EGFR,GNAS,CDKN2C,TSC1,RB1,CTNNB1,JAK1,CDH1,PTEN,GATA2,FGFR2,MSH2,SMO,PIK3CA,JAK3,MSH6,PRKAR1A |
| 1.665e-03 | -6.40 | POOLA_INVASIVE_BREAST_CANCER_DN | MSigDB lists | POOLA_INVASIVE_BREAST_CANCER_DN | 130 | 32 | 17758 | 2588 |
KLK10,FRMD4A,NQO1,PEX6,SDC4,FBXO2,GATA3,COL4A5,TP53I11,LTBP3,IL17RB,PDGFA,CYP1A1,ITGA3,IGF1R,SLC27A6,XYLT2,IGFBP2,CACNA1D,ECE1,SSH3,CELSR2,PIK3R1,KCTD2,ACADSB,ITGA7,MATN2,MYLK,ITPR1,INPP4B,CLMN,SERPINB5 |
| 1.670e-03 | -6.39 | GSE22886_DC_VS_MONOCYTE_DN | MSigDB lists | GSE22886_DC_VS_MONOCYTE_DN | 189 | 43 | 17758 | 2588 |
GSDMD,KLF2,CCDC109B,ZNF395,IL15,HLA-F,TSC22D3,FLOT1,SELL,BTN3A1,NOTCH2,IGF1R,SP100,CNTRL,ZFP36,MTMR11,PIK3CD,CNPY3,CDKN2D,EEF1D,CKAP4,DUSP1,GCA,ELK3,ING1,CD55,PLSCR1,KIAA1109,C15orf39,FOS,CRISPLD2,ATP13A2,IRS2,BTG1,FYN,HPSE,SERPINA1,SEMA4D,STK38,RIN3,NOD2,IRF7,IRF1 |
| 1.670e-03 | -6.39 | GSE27786_LIN_NEG_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NEUTROPHIL_DN | 189 | 43 | 17758 | 2588 |
HECA,INPPL1,NFKBIE,GPR107,CPEB4,TRIM5,CAST,HLA-E,TMX4,NRG2,TXNDC9,CAMK1D,ADAMTSL4,DDR1,PHF1,CMTM6,NFAT5,FAM111A,NOV,INPP5E,MLPH,SLC16A6,MCF2L,FAM13B,CITED2,RAG1,IL1RAP,UPF3A,KRT80,TRIM8,B3GNT2,TACC1,OSTM1,MPP1,SHARPIN,RC3H2,SPATA13,ZFAND5,TRAM2,TMEM30A,S100A5,SERPINB1,RARG |
| 1.670e-03 | -6.39 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | 189 | 43 | 17758 | 2588 |
DAP,NDRG1,ABCG2,KIF23,GRK6,FAM101B,SPSB1,RPS6KA2,OXCT1,IGF1R,RALGPS2,IL6ST,SLC44A1,CD9,BRD7,STT3B,DLG3,MPHOSPH9,PSMA5,SMC4,EPHX1,P2RX4,CASK,CXXC5,MPP1,PLAUR,TNFAIP8L1,RAB3IP,ZFAND5,SESN1,CYB5A,CD8A,TMEM50B,FNTA,ETS2,TWSG1,DCK,WFS1,NAB2,HDAC1,ACADM,JARID2,FAM134B |
| 1.670e-03 | -6.39 | GSE7852_TREG_VS_TCONV_LN_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_LN_DN | 189 | 43 | 17758 | 2588 |
EPAS1,IBTK,PEX6,DAP,ELOVL7,MCTP2,FAM78A,GPSM2,SNN,SEPP1,FAM101B,DENND2D,TTYH3,PARM1,TGFBR3,CYP2S1,EXOC8,UBE2J1,DUSP10,IL17RA,SGK1,FAM102A,TAGLN2,CNGA1,WNT3A,ALS2CL,SLC16A5,SLC5A11,RGMB,TCF7,ATP1B1,RASGRP2,XKRX,MAMDC4,LDLRAP1,SMTNL2,C1orf21,ITPR1,NR4A3,APPL2,HS3ST3B1,ST3GAL1,ADAMTS16 |
| 1.670e-03 | -6.39 | GSE3982_DC_VS_BASOPHIL_DN | MSigDB lists | GSE3982_DC_VS_BASOPHIL_DN | 189 | 43 | 17758 | 2588 |
REPS2,CNOT8,OSGIN2,AKAP17A,CCNL1,NUCB2,MAP1LC3B,KBTBD11,IL18R1,PHF1,SLC25A36,TTC21B,CARD8,DNAH6,OSBPL3,PASK,KLF3,ZDHHC13,BRD7,PDE4D,MYRIP,APOBEC3G,MPHOSPH9,CTDSP2,RHOA,FBLN5,BCL7B,SPTLC2,ZDHHC3,GALNT3,SFXN1,TMEM164,PPP2R5A,ETS2,PAFAH1B3,WIPI1,KBTBD2,STK38,UBE2D2,PPM1H,EIF4EBP2,CHPT1,JARID2 |
| 1.670e-03 | -6.39 | GSE3982_DC_VS_MAC_DN | MSigDB lists | GSE3982_DC_VS_MAC_DN | 189 | 43 | 17758 | 2588 |
PRKAA2,GOLIM4,SEC61G,TSC22D3,ITGA6,CTDSPL,RGS20,TGFBR1,BAIAP3,CCNB1,HERC6,S100A2,PCBP1,HOXB2,TIPRL,SLC9A7,AP1M2,CCNA2,RNF128,KIF13B,SORL1,CRTAP,HMMR,CENPA,AGPS,PKMYT1,ZDHHC3,VCP,TRIM9,DCTN6,SERPINA1,NGFRAP1,RND3,CSF1,FAM114A1,WDR19,WWTR1,NXPH4,AURKA,CENPE,AKIP1,CCNB2,PKIA |
| 1.670e-03 | -6.39 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | 189 | 43 | 17758 | 2588 |
SPC25,DLGAP5,FOXM1,MCTP2,KIF23,GPSM2,PHLDA1,FLT3,DUSP5,FZD6,PLS3,CAPN2,APOBEC3B,PCNA,CCNA2,RGS3,KIF22,RASGRP1,SMC4,FAM69A,CTH,CKS2,PGM1,ZWINT,PBK,FHL2,PTGER4,GGH,AURKB,DUSP4,CCNF,POLD3,FRMD4B,SFXN1,FAM64A,P4HA2,NETO2,AURKA,KPNA2,CBX5,ESPL1,E2F8,RPS6KA3 |
| 1.671e-03 | -6.39 | WEST_ADRENOCORTICAL_TUMOR_UP | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_UP | 284 | 60 | 17758 | 2588 |
KIF3C,SLC25A24,CDK17,TXN,FOXM1,TUBB4B,TMEM41B,CNOT8,PTTG1,CDCA3,RACGAP1,TXNDC9,KIF2C,SLC1A3,CCNB1,ERP29,SLC20A1,BARD1,FANCI,TOP2A,KIF5B,ATP6V0B,HSF2,KHNYN,ELMO2,KIF14,PSMC2,PRC1,NEK2,RPN2,BUB1,HSPA13,EPB41L4B,SMC4,ABCC1,UFD1L,ZWINT,KIF20A,LGALS8,ASPM,PBK,GGH,GLO1,ICMT,CDC25C,CDK1,ZMPSTE24,TSC1,ATP1A1,TMEM30A,HOXA9,P4HA2,SLC2A6,PLA2G15,HDAC1,AURKA,SLC31A2,ESPL1,MELK,ACOT7 |
| 1.678e-03 | -6.39 | AR (androgen receptor) | protein interactions | 367 | 272 | 62 | 16036 | 2547 |
CASP3,PAX6,RUNX2,TRIM24,REPS2,SUZ12,CUL4B,ETV5,TP53,AES,TRIM68,APPBP2,ELF3,CALR,CCND1,PAK6,RB1,CTNNB1,PTEN,IL6ST,GTF2F2,PRKG1,ERCC2,NR2C1,CTDSP2,NCOA2,SIRT1,SMARCA2,TGIF1,DDB2,DCAF6,AKT1,NR3C1,UXT,CALM1,FHL2,WHSC1,KDM3A,CDK1,RANBP9,VCP,EGFR,KDM4D,PIAS3,NCOA3,IDE,CASP7,SLC25A4,WIPI1,RBL1,E2F1,PIAS2,HDAC1,RNASEL,ZMIZ1,NDE1,NR3C2,AHR,APOL2,HIPK3,FOXA1,NR2C2 |
| 1.680e-03 | -6.39 | ephrin receptor signaling pathway | biological process | GO:0048013 | 92 | 25 | 16441 | 2455 |
MYL9,RHOA,ARHGEF28,ARHGEF7,EPHA4,GRIN1,EPHA1,YES1,EFNB1,MYL12A,RASA1,CDK5R1,EPHA10,SS18,FYN,LIMK1,SIPA1L1,EFNA5,EFNA1,MYH14,EPHB4,ARPC2,TIAM1,MYL12B,NGEF |
| 1.687e-03 | -6.38 | cell-cell adherens junction | cellular component | GO:0005913 | 55 | 17 | 17570 | 2579 |
PVRL4,CAMSAP3,SORBS1,NDRG1,FLOT1,PLEKHA7,SCRIB,DAG1,ZYX,CTNNB1,CDH1,PVRL2,CDH3,TLN2,SHROOM2,FLOT2,SMAGP |
| 1.693e-03 | -6.38 | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | 162 | 38 | 17758 | 2588 |
GALK1,MTM1,CTHRC1,SERPINE2,CKAP2,DDIT4L,TAP1,TP53,DUSP5,FGF19,CCND1,CPNE2,PFKL,CALD1,GPC3,BAX,DAPK1,EGLN3,WNT3A,C12orf75,ZNF365,RNF169,DNAI1,IGDCC4,PGM1,ARAP2,PSRC1,PQLC3,WNT10B,MAPKAPK3,SALL4,PLK2,PTK7,PIEZO1,CD81,CPPED1,DEF6,EGLN1 |
| 1.708e-03 | -6.37 | ear development | biological process | GO:0043583 | 201 | 46 | 16441 | 2455 |
CTHRC1,USH1C,SOX9,SDC4,CCM2,MCOLN3,SLC25A27,GATA3,JAG2,OSR2,PLPPR4,TMC1,SLC9A3R2,SIX4,FZD6,GBX2,PLS3,BMP2,GATA2,ALDH1A3,TFAP2A,ATP8B1,CDKN1B,TWIST1,ECE1,WNT3A,NTN1,GFI1,SPRY2,DVL2,HES1,SOD1,DCHS1,SCRIB,PRKRA,ABR,MAPKAPK2,FAT4,FGFR2,PTK7,TBX1,TBX18,LRIG1,NR4A3,OSR1,SHROOM2 |
| 1.710e-03 | -6.37 | kinase activator activity | molecular function | GO:0019209 | 59 | 18 | 16491 | 2452 |
NKX3-1,IQGAP1,CALM1,RGCC,CALM3,CDK5R1,BCL10,CALM2,PRKAG2,GPRC5B,MADD,PAK2,PIK3CA,CAB39,NRG1,EFNA5,ERBB3,SPRY2 |
| 1.728e-03 | -6.36 | homeostasis of number of cells | biological process | GO:0048872 | 185 | 43 | 16441 | 2455 |
EMX1,KLF2,CASP3,DYRK3,ADD1,LGR4,EPAS1,THRA,SOX9,P2RX7,GATA3,PKN1,FLT3,MECOM,NOV,RB1,TGFBR3,GATA2,SIVA1,BCL6,SMO,BAX,ERCC2,PIK3CD,ZBTB18,RAG1,F2R,SOD1,AKT1,DMTN,RC3H2,NFE2L1,SLC11A2,FAS,FECH,SFXN1,CSF1,AXL,PTBP3,PPP2R3C,JAK3,CCNB2,SLC25A38 |
| 1.729e-03 | -6.36 | human chr10q26 | chromosome location | human chr10q26 | 18 | 7 | 26250 | 2805 |
ATRNL1,WDR11,OAT,TACC2,PTPRE,FGFR2,DPYSL4 |
| 1.731e-03 | -6.36 | regulation of cell activation | biological process | GO:0050865 | 460 | 92 | 16441 | 2455 |
LAMP1,CASP3,IL15,INPP5D,RPS6KA1,GATA3,ERBB2,IL27RA,IL18,EGR3,CD274,SLC7A2,PDGFB,FLT3,TNFSF9,PDGFA,CD46,CTNNB1,CTGF,IL6ST,LMO4,IL31RA,BCL6,PIK3CA,DLG1,SLC39A10,PTPRE,FLOT2,RASGRP1,SOD1,CD55,RIPK2,AKT1,LGALS8,ITCH,DMTN,PRKCQ,CD40,ABR,IRS2,FYN,AXL,STAT6,NOD2,F2RL1,PRKAR1A,LGALS3,SERPINE2,DHPS,TRAF2,UBASH3B,HLA-E,TEC,PKN1,MERTK,EFNB1,HLA-A,RAC2,FBXO7,PAK2,PRKG1,IGFBP2,C10orf54,WNT3A,RAG1,MAP3K7,SYK,MSH6,SOCS5,HES1,RHOA,PLSCR1,PIK3R1,VAMP3,PDE5A,WHSC1,YES1,FAS,SOX13,CD83,BCL10,BANK1,PVRL2,NR4A3,PPP2R3C,GPER1,ICOSLG,CD81,NDFIP1,JAK3,AHR,IRF1 |
| 1.733e-03 | -6.36 | E-cadherin signaling in the nascent adherens junction | Pathway Interaction DB | ecadherin_nascentaj_pathway | 33 | 15 | 2227 | 480 |
CCND1,RHOA,AKT1,CDH1,CTNNB1,IQGAP1,PIK3R1,DLG1,PIK3CA,CTNND1,CTTN,NCKAP1,CYFIP2,ARF6,TIAM1 |
| 1.733e-03 | -6.36 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | 173 | 40 | 17758 | 2588 |
DYRK3,ACVR1,TXN,GNPDA1,TMEM55B,SNX9,SPP1,SH3D21,ANKS6,ADCK2,SGK1,BRI3,TNFRSF12A,PTPRE,SPRY2,WBP5,CKS2,MFI2,LONRF3,PLEKHO1,LHFPL2,STX3,RHEB,RHOB,BCAR3,ANKRD10,SLCO4A1,SCARB2,SERTAD2,PRKAG2,CSF1,CORO1C,ITPR1,NR4A2,MAPK13,GLA,GEM,NRBP1,ZC3HC1,RRAGD |
| 1.736e-03 | -6.36 | DNPEP (aspartyl aminopeptidase) | protein interactions | 23549 | 27 | 11 | 16036 | 2547 |
TRIM47,TNS3,DNPEP,UGP2,PLOD2,MPP1,SAT1,KCTD12,ADAMTSL4,TBC1D4,MDFI |
| 1.740e-03 | -6.35 | regulation of cell morphogenesis | biological process | GO:0022604 | 530 | 104 | 16441 | 2455 |
SSH1,EPHA4,HEXB,RET,PLXNA1,MNS1,SH3KBP1,CTNNB1,CDKL5,DPYSL2,DLG1,DNM2,DAB2IP,TWIST1,TACSTD2,MYH14,SEMA3G,CTTN,TIAM1,S100A13,TBC1D10B,SEMA3B,SSH3,SYNE3,STRIP2,DMTN,EZR,DAG1,ULK2,ARHGAP35,TBC1D17,FYN,SHROOM3,BHLHB9,CORO1C,LIMK1,WWTR1,SIPA1L1,TRIOBP,STAT1,EFNA5,NRG1,PLXND1,ITPKA,MYL12B,LZTS1,FGD1,WASF3,SEMA6B,FBLIM1,TAOK2,ARAP3,BVES,TBC1D1,SH3D19,CIT,ARHGEF7,EPS8,LRP4,TGFBR1,CRABP2,FAM21C,FBLN1,ICAM1,CORO1B,BMP2,CALR,SPP1,PTEN,KNDC1,MEGF8,VASN,KIF13B,TNFRSF12A,WNT3A,NTN1,ZRANB1,TRIM62,RIMS2,EPB41L5,RHOA,MFI2,RAPGEF2,GRIN1,RGCC,ILK,CDK5R1,RASA1,MAP1B,AP1AR,SEMA4D,HTT,ITGA7,CSNK1G1,ARAP1,FGD6,EFNA1,ARPC2,SEMA3A,SHOX2,L1CAM,FOXA1,ADAMTS16,NGEF |
| 1.745e-03 | -6.35 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP | 471 | 92 | 17758 | 2588 |
CASP3,GPR107,GRIK2,TMEM217,TRIP10,BROX,CD82,NRG2,IL18,BCL2L1,SNN,EMP2,PDGFB,TNFSF9,CARD10,KREMEN1,IER3,TP73,NKAIN3,RTKN2,ARL4D,NFKB2,NEB,FGFR1OP2,PLK1,SPEF2,CD55,RIPK2,FZD4,PIF1,RNF19B,FZD7,DPYSL3,PTGS2,KLF12,BHLHB9,KLF5,HS3ST3B1,MIIP,COBL,PRR15,MAFF,NKX3-1,TAOK2,GOLIM4,DYRK3,ELOVL7,SDC4,HAL,ICAM1,ZDHHC21,FOXP2,TNS3,ITGB8,GPC3,MCF2L,DRAM1,ABCD1,MAPK11,MDFIC,PIKFYVE,DGKG,ATP2B1,IGSF3,ADAM17,FMN1,BTNL9,RAPGEF2,PLAUR,MRS2,LITAF,PIM3,TP53INP2,EGFR,CD83,IL1R1,GABRD,SEC14L4,MFSD2A,CSF1,NFKBIA,SLC2A6,AGBL5,OTUB2,PLD1,GEM,DRP2,ICOSLG,HIPK3,FOXA1,TLL2,EHD1 |
| 1.747e-03 | -6.35 | phospholipid transporter activity | molecular function | GO:0005548 | 50 | 16 | 16491 | 2452 |
PLSCR4,PLSCR1,ATP9A,ATP8A1,ANO6,ATP8B3,ANO9,PCTP,CPTP,ATP10D,MFSD2A,ATP8B1,PITPNA,ANO4,ABCA1,ABCG1 |
| 1.747e-03 | -6.35 | human chr8p21.3 | chromosome location | human chr8p21.3 | 33 | 10 | 26250 | 2805 |
NPM2,PHYHIP,ENTPD4,CSGALNACT1,BMP1,RHOBTB2,LGI3,SORBS3,LOXL2,REEP4 |
| 1.749e-03 | -6.35 | Programmed Cell Death | REACTOME pathways | R-HSA-5357801 | 163 | 39 | 8202 | 1235 |
CASP3,BMF,ADD1,PSME2,TRAF2,XIAP,TP53,PSMD7,PSMD10,PSME1,BCL2L1,BCAP31,LMNA,DAPK2,PSMD1,CTNNB1,CDH1,PAK2,PSMC2,DAPK1,BAX,PSMA5,PSMB4,AKT1,CASP9,PRKCQ,PSMA4,FAS,CASP7,FNTA,STK26,H1F0,DNM1L,PSMD3,E2F1,MLKL,UNC5B,PSMC1,OCLN |
| 1.752e-03 | -6.35 | Gastric cancer network 2 | WikiPathways | WP2363 | 34 | 13 | 4455 | 729 |
TOP2A,OTUD5,COL9A3,CTNNB1,UBE2T,TP53,FAM91A1,RAD17,UBE2C,LBR,S100A6,FANCI,EGFR |
| 1.757e-03 | -6.34 | BLALOCK_ALZHEIMERS_DISEASE_DN | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_DN | 1209 | 212 | 17758 | 2588 |
GAA,TXN,MRPS15,CRYM,EPHA4,HEXB,MCCC1,CUL1,OAT,CALM2,EPCAM,PAK6,PCNA,PSMD1,HSF2,ELMO2,SHC3,CABP1,ARL1,PHTF1,PSMC2,PAPSS1,TRPC1,ASH2L,ARNT2,NFU1,WBP4,PTPRE,SMARCA2,SH3BGRL,RNF11,BNIP3L,PRKAR2B,LDB2,SLC25A5,ULK2,RHEB,VCP,ARF4,DNM1L,KCNK1,PLK2,SH3GLB2,CAB39,ADIPOR1,MRPS28,SERPINI1,KPNA2,ITPKA,APBA2,NRGN,LZTS1,RTN3,MYL12B,DLAT,RECQL,CDK17,PPP1R12A,PPP1R2,ASAH1,CALM3,NDUFA4,TXNDC9,CNTNAP2,RAB6A,COX6C,DUSP5,HPCAL4,TSPAN7,B4GALNT1,CALR,ATP5H,PRKCI,MSH2,SRP54,RFX5,NPTN,ACAD8,MOXD1,GAD1,TMED2,RIMS2,PSMA5,MCCC2,FAM69A,CYP26B1,PMPCB,MMD,OXR1,CALM1,EIF2AK1,SRSF5,RANBP9,CDK5R1,GNAS,FECH,UAP1,ETS2,ITPR1,C1orf21,SLC4A3,PITPNA,MDH1,ARPC2,TMEM14A,C17orf75,RUSC1,KIF3C,DYNLRB1,NF2,UGP2,NQO1,TUBB4B,RGS20,CCNL1,FAM198B,SNN,CDK14,APLP2,NOV,ZNF75D,TACC2,RALB,LMO4,RPN2,GOT1,IFIT1,PDE4D,SCN2A,PDIA6,SNX10,CDKN2D,NR2C1,SCN3A,CKS2,LGALS8,SEPT6,DRAP1,SAT1,PTGER4,COX11,GLO1,BCL7B,ATP1B1,GTF2A2,H2AFV,PDHX,ATP13A2,ALDH5A1,DDOST,NGFRAP1,AXL,SLC9A6,STAT1,MAOA,RCAN2,RGS14,PRKAR1A,CDS2,ARHGEF3,PINK1,ENO2,GNAL,ARL4C,PSMD10,AES,DNAJB9,COX7A2,CCDC92,DIRAS3,OXCT1,PTEN,CDK16,H2AFY,TMBIM6,TSPAN13,HSPA13,CASD1,SLC35A1,ATP2B1,DLGAP1,MOB4,PCCB,PGM1,ADAM17,ALDH2,DCAF6,PSMB4,MPP1,AMFR,UBE2A,STMN3,CAPNS1,MAPK8IP1,PRDX4,USP6,FUCA1,DCTN6,HLA-B,PRDX3,CCDC6,SPINT2,PGRMC1,NETO2,ABCB1,FHL1,ATP6V1C1,NDFIP1,L1CAM,ARHGEF9,ACOT7,ARHGEF4 |
| 1.757e-03 | -6.34 | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 184 | 42 | 17758 | 2588 |
ARAP3,MRPS15,DHPS,CENPI,TRAF2,RAB23,GALM,PM20D2,KTN1,NFAT5,CYHR1,CPNE2,BAX,IRF2,ZNF692,HEXIM2,ETHE1,IL10RB,C12orf75,DVL2,DDB2,HPS3,FIGNL1,CTNNAL1,MAPKAPK3,CDYL,WHSC1,LRRC1,ITPR3,POLD3,PRDX4,DHX32,PIAS3,MAMDC4,STX10,FAM64A,SH2D3C,DBI,DHTKD1,FAM195A,ACADM,TMEM120A |
| 1.761e-03 | -6.34 | RHO GTPases Activate ROCKs | REACTOME pathways | R-HSA-5627117 | 17 | 8 | 8202 | 1235 |
MYL9,RHOA,PPP1R12A,LIMK1,PPP1CB,MYH14,MYL12B,RHOB |
| 1.761e-03 | -6.34 | Glycogen breakdown (glycogenolysis) | REACTOME pathways | R-HSA-70221 | 17 | 8 | 8202 | 1235 |
CALM2,GAA,PGM1,CALM1,PYGL,CALM3,PHKA2,PHKG2 |
| 1.761e-03 | -6.34 | activated TAK1 mediates p38 MAPK activation | REACTOME pathways | R-HSA-450302 | 17 | 8 | 8202 | 1235 |
MAPKAPK2,IRAK1,RIPK2,TAB3,MAPKAPK3,NOD2,MAPK11,MAP3K7 |
| 1.762e-03 | -6.34 | V$LEF1_Q6 | MSigDB lists | V$LEF1_Q6 | 245 | 53 | 17758 | 2588 |
SORBS1,HOXB7,MPZL1,DGKA,GABRG2,COL18A1,BAHD1,SDC1,TNFRSF19,PCBP1,SIX4,NRP2,FOXP2,WEE1,SESN3,IGF1R,SHC3,RGS3,MCF2L,BMP7,ELF5,KLF3,CLDN4,ABCD1,PIM1,PDE4D,TGIF1,ELK3,HMGN5,SH3BGRL,SERTAD4,CRIP2,TCF7,AIF1L,ZFAND5,DPYSL4,RNF19B,STEAP1,CDK5R1,ABR,EBF2,DPYSL3,BCAR3,HS6ST1,PTPRJ,CORO1C,NKD1,MAP3K11,EFNA1,SPRY4,LIFR,FOXA1,PHC1 |
| 1.766e-03 | -6.34 | GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDM_DN | 195 | 44 | 17758 | 2588 |
PLA2G4A,SLC41A1,UBE2Z,PKP2,DNAJB11,COL4A5,CD274,CNTNAP2,SDC1,PDGFB,ICAM1,MECOM,RPS6KA2,GATA2,ZFP36,FOSB,PIM1,TIPARP,SYK,RASGRP1,NCOA2,TMCC2,RIPK2,TNIP1,SPATA13,UBE2A,PIM3,YES1,RNF19B,KIF11,TP53INP2,SNX12,JAK1,ETS2,SHROOM3,RND3,RELL1,FHL1,ICOSLG,ST3GAL1,CBX4,CYBRD1,KLF7,USP16 |
| 1.767e-03 | -6.34 | RB_DN.V1_DN | MSigDB lists | RB_DN.V1_DN | 120 | 30 | 17758 | 2588 |
SEC23A,AGRN,CTNNAL1,PSME2,USP18,NDRG1,FURIN,IRX4,COL18A1,PSME1,CDIPT,PDGFB,KIAA1161,TMCC3,TMEM50B,RB1,CTSC,ARL1,CD9,FAM102A,FHL1,LMAN1,MOXD1,F2RL1,SERPINB1,LIFR,ANXA11,STARD3NL,PRKAR1A,TUBA4A |
| 1.770e-03 | -6.34 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN | 157 | 37 | 17758 | 2588 |
MPZL1,TMEM217,CAMKK1,PATL2,NFAT5,MXD1,SCML1,SUN3,IFIT1,DDX59,MX1,SIRT1,TGIF1,PAPD7,NR4A1,PTGER4,BTBD19,KBTBD8,PIM3,IFIT3,TP53INP2,RHOB,MAPK8IP1,GPLD1,IRS2,PTGS2,AREG,WDR19,NR4A3,RAB11FIP1,ZNF165,IRF7,NR4A2,HOXB13,GEM,NIPA1,IRF1 |
| 1.775e-03 | -6.33 | Prostate cancer | KEGG pathways | hsa05215 | 89 | 25 | 6908 | 1076 |
CCNE2,PDGFC,NKX3-1,HSP90B1,AKT1,PIK3R1,CASP9,TP53,ERBB2,TCF7,PDGFB,GSTP1,EGFR,PDGFA,CCND1,RB1,CTNNB1,IGF1R,PTEN,FGFR2,NFKBIA,E2F1,PIK3CA,CDKN1B,PIK3CD |
| 1.775e-03 | -6.33 | Prostate cancer | KEGG pathways | ko05215 | 89 | 25 | 6908 | 1076 |
CCNE2,PDGFC,NKX3-1,HSP90B1,AKT1,PIK3R1,CASP9,TP53,ERBB2,TCF7,PDGFB,GSTP1,EGFR,PDGFA,CCND1,RB1,CTNNB1,IGF1R,PTEN,FGFR2,NFKBIA,E2F1,PIK3CA,CDKN1B,PIK3CD |
| 1.781e-03 | -6.33 | REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING | MSigDB lists | REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING | 42 | 14 | 17758 | 2588 |
AKT1,PTEN,NR4A1,CASP9,PIK3R1,PIK3CA,CDKN1B,NRG2,ERBB2,NRG1,ERBB3,PHLPP1,GAB1,EGFR |
| 1.781e-03 | -6.33 | positive regulation of cell cycle process | biological process | GO:0090068 | 245 | 54 | 16441 | 2455 |
DLGAP5,CIT,PSME2,NDRG1,CUL4B,PSMD7,TP53,KIF23,PSMD10,RACGAP1,PSME1,CCNB1,PRKACA,PDGFB,TP73,NPM2,CCND1,E2F7,RB1,CYP1A1,PSMD1,CTGF,IGF1R,PTEN,KIF14,PSMC2,PLK4,CDKN1B,DAB2IP,PSMA5,PLK1,RHOA,WNT10B,PSMB4,VPS4B,RGCC,NUSAP1,KIF20B,AURKB,PSMA4,CDK5R1,NUDT16,INSR,PSMD3,CDCA5,FAM83D,AURKA,XRCC3,PKD2,GEN1,UBE2C,E2F8,ESPL1,PSMC1 |
| 1.781e-03 | -6.33 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | 51 | 16 | 17758 | 2588 |
ORAI2,PLSCR1,CYP2J2,EPHA4,AIF1L,ANO1,NFIB,PARM1,FAS,PLEKHH2,CSF1,ENPP5,STEAP2,RGS5,IL1RAP,PCSK5 |
| 1.783e-03 | -6.33 | neuron spine | cellular component | GO:0044309 | 109 | 28 | 17570 | 2579 |
MOB4,P2RX4,FARP1,EPHA4,GRIN1,STRN4,FBXO2,PRKAR2B,SLC1A3,ARF4,GRM5,CDK5R1,MAP1B,ADORA1,GRID2IP,PTEN,ANKS1B,SLC9A6,SIPA1L1,ARRB1,GPER1,CTTN,PPP1CA,ITPKA,RGS14,NRGN,LZTS1,DRD1 |
| 1.786e-03 | -6.33 | Sass6 (spindle assembly 6 homolog (C. elegans)) | protein interactions | 72776 | 13 | 7 | 16036 | 2547 |
PPP1CB,MPRIP,PPP1CA,PPP1R12A,CALD1,CORO1C,PLS3 |
| 1.800e-03 | -6.32 | peptidase activator activity | molecular function | GO:0016504 | 37 | 13 | 16491 | 2452 |
CARD8,PINK1,NKX3-1,PCOLCE,CTSC,NGFRAP1,PSME2,CDKN1B,PSME1,BCL2L13,FBLN1,VCP,EBAG9 |
| 1.802e-03 | -6.32 | single-organism membrane organization | biological process | GO:0044802 | 786 | 147 | 16441 | 2455 |
DOC2A,SUN1,AGRN,GRIK2,ATP8A1,MPP5,F11R,SYTL4,CCNB1,SNX9,SPTB,PICK1,RAB15,NUP210,DLG1,SUN3,RAB20,PACSIN1,TFG,ANO4,TRAM1,CPE,XKR8,PLK1,VPS11,SOD1,KCNIP3,SYNE3,BNIP3L,EZR,ARFRP1,KIF13A,ICMT,MCFD2,CDK1,OPTN,DNM1L,AREG,TC2N,SEC61G,ETV5,CNTNAP2,LMNA,ATG4A,RPL39,KCNN4,PRKCI,SRP54,PPP6R1,SYTL3,NUP85,TMED2,TSPAN33,GCC2,ANO6,ATP8B3,ZDHHC3,EGFR,FA2H,HTT,TMEM30A,ZDHHC20,RAB31,ZDHHC7,DYSF,ATP1B3,CCNB2,NUP58,DMPK,NDRG1,APOO,TP53,PKP2,P2RX7,BCL2L1,EMP2,SYTL2,CDH1,ZDHHC12,REEP1,ZDHHC23,RPN2,LMAN1,DLG3,FLOT2,ATG4D,PPIF,SEC23A,BAG4,SEC61B,AKT1,TMEM43,SYNE2,SYP,RAB38,ATP1B1,ATP10D,ZMPSTE24,PEX5,DDOST,CHMP4B,SYT13,RPL22,REEP4,ABCA1,CNEP1R1,COPG1,PLSCR4,PACSIN2,TAOK2,TRAPPC10,TSPAN15,ATP9A,LRP4,FLOT1,CTSZ,ANO9,TSPAN17,ZDHHC21,ANK1,ADORA1,CTSC,PTEN,A4GALT,BAX,CD9,PLEKHF1,ATP8B1,MYO5A,SUN2,RAB3B,PLSCR1,CRB3,RAPGEF2,VAMP3,COL7A1,RAB3IP,BBS2,LEMD2,RPL12,SERPINA1,FAT4,SYT7,SSNA1,SPCS3,GPER1,NUP37 |
| 1.805e-03 | -6.32 | PDZ domain binding | molecular function | GO:0030165 | 83 | 23 | 16491 | 2452 |
DOCK4,CLCN3,ADAM17,GRIK2,FZD4,CIT,RAPGEF2,F11R,APBA1,SNTB1,SLC9A3R2,ARHGEF16,FZD7,CXXC4,SNTA1,TGFBR3,LLGL2,PTEN,KIF14,NKD1,SRR,DLG3,ATP2B1 |
| 1.820e-03 | -6.31 | UBB (ubiquitin B) | protein interactions | 7314 | 140 | 36 | 16036 | 2547 |
FAF2,TRIM5,DNAJB2,SUZ12,UBASH3B,XIAP,ASB9,TP53,ERBB2,TGFBR1,FBXO6,HDAC6,HLA-A,SH3KBP1,RAD23A,PCNA,TUBG1,CDKN1B,USP1,SYK,DUSP1,TRAPPC13,NR3C1,SPRTN,RNF11,CDC20,MYBL2,AURKB,VCP,EGFR,EPN3,MAGED2,UBE2D2,AURKA,ARRB1,APOL2 |
| 1.825e-03 | -6.31 | Band_41_domain | interpro domains | IPR019749 | 51 | 16 | 18293 | 2672 |
FRMPD3,EPB41L5,FARP1,FRMD4A,NF2,FRMD6,EZR,FRMD4B,PLEKHH2,JAK1,EPB41L4B,EPB41L4A,TLN2,MYLIP,JAK3,FARP2 |
| 1.826e-03 | -6.31 | fallopian_tube-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | fallopian_tube-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 14 | 7 | 17775 | 2585 |
CTNNB1,AKT1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 1.826e-03 | -6.31 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-juvenile_xanthogranuloma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-juvenile_xanthogranuloma | 14 | 7 | 17775 | 2585 |
ERBB2,AKT1,IDH1,PTEN,EGFR,PIK3CA,TP53 |
| 1.826e-03 | -6.31 | juvenile_xanthogranuloma | COSMIC cancer mutations | juvenile_xanthogranuloma | 14 | 7 | 17775 | 2585 |
ERBB2,AKT1,IDH1,PTEN,EGFR,PIK3CA,TP53 |
| 1.826e-03 | -6.31 | soft_tissue-blood_vessel-haemangioma-epithelioid | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma-epithelioid | 14 | 7 | 17775 | 2585 |
TSC1,PLCG1,CTNNB1,AKT1,IDH1,PTEN,PIK3CA |
| 1.826e-03 | -6.31 | vagina-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | vagina-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 14 | 7 | 17775 | 2585 |
CTNNB1,AKT1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 1.828e-03 | -6.30 | negative regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043124 | 50 | 16 | 16441 | 2455 |
SIRT1,RHOA,TNIP1,NLRX1,LITAF,PSMD10,CARD19,GSTP1,OPTN,NOV,CARD8,BMP7,NFKBIA,STAT1,TLE1,DAB2IP |
| 1.828e-03 | -6.30 | condensed chromosome kinetochore | cellular component | GO:0000777 | 94 | 25 | 17570 | 2579 |
PLK1,REC8,ZWINT,CENPA,SPC25,HJURP,CENPC,SEPT6,NDC80,ERCC6L,NUF2,KIF2C,CCNB1,SPDL1,SKA1,CENPN,DCTN6,NEK2,BUB1,CENPE,KNTC1,NDE1,NUP37,SGOL1,NUP85 |
| 1.831e-03 | -6.30 | DNASE2B (deoxyribonuclease II beta) | protein interactions | 58511 | 31 | 12 | 16036 | 2547 |
CAPN2,WIPI1,TMTC3,CERCAM,TRAF2,PASK,GALNS,SUCO,IL17RA,GALNT7,PPP2R5D,TUBA4A |
| 1.831e-03 | -6.30 | CACTGCC,MIR-34A,MIR-34C,MIR-449 | MSigDB lists | CACTGCC,MIR-34A,MIR-34C,MIR-449 | 268 | 57 | 17758 | 2588 |
CCNE2,TMEM184B,FRMD4A,LGR4,XYLT1,OSGIN2,CNTNAP2,GRK6,NOTCH2,MGAT5B,FAM167A,PPP2R3A,C1orf116,TMCC3,ZCCHC17,RALGPS2,PPP1R10,LMAN2L,MGAT4A,FUT8,BCL6,ZDHHC23,SLC44A2,VAT1,DIXDC1,ACSL4,IQGAP3,NCEH1,MYRIP,STK35,HCN3,PGM1,TAF5,CAPN6,ACBD3,FOXJ2,NFE2L1,VEZT,TRIM35,ALCAM,DPYSL4,ABR,COL12A1,SGPP1,GLCE,CNTNAP1,RTN4RL1,PPP2R5A,KLF12,AXL,CORO1C,CSNK1G1,MPP2,FGD6,NR4A2,RARG,PKIA |
| 1.835e-03 | -6.30 | Interferon gamma signaling | REACTOME pathways | R-HSA-877300 | 92 | 25 | 8202 | 1235 |
TRIM8,TRIM2,TRIM5,HLA-E,HLA-F,TRIM35,TRIM68,ICAM1,HLA-A,SOCS3,HLA-B,JAK1,SP100,TRIM45,STAT1,TRIM3,IRF2,TRIM21,IRF7,HLA-C,OAS3,NCAM1,TRIM62,CAMK2G,IRF1 |
| 1.836e-03 | -6.30 | QI_HYPOXIA | MSigDB lists | QI_HYPOXIA | 136 | 33 | 17758 | 2588 |
NDRG1,SOX9,PKP2,NDRG2,IL13RA1,TNFSF9,IER3,CD109,PFKL,CYP2S1,REEP1,HMGCL,ESPN,OSTF1,DIXDC1,EGLN3,DUSP1,PGM1,KDELR3,KDM3A,COL12A1,ZNF469,PGF,CTNS,HPSE,PAFAH1B3,PLOD2,P4HA2,TRIOBP,MPP2,EFNA1,SLC27A3,EGLN1 |
| 1.837e-03 | -6.30 | RACGAP1 (Rac GTPase activating protein 1) | protein interactions | 29127 | 39 | 14 | 16036 | 2547 |
PSMD1,MPRIP,PRSS23,PPP2R4,PRC1,TUBG1,KIF23,CUL1,RACGAP1,AURKB,TXNDC11,CDK1,SH3KBP1,TUBA4A |
| 1.840e-03 | -6.30 | transmembrane receptor protein tyrosine kinase activity | molecular function | GO:0004714 | 64 | 19 | 16491 | 2452 |
EPHA4,RET,ERBB2,PDGFRL,ROR1,EPHA1,MERTK,FLT3,DDR1,EGFR,NRP2,EPHA10,INSR,IGF1R,FGFR2,AXL,RYK,EPHB4,NPTN |
| 1.840e-03 | -6.30 | phosphatase regulator activity | molecular function | GO:0019208 | 88 | 24 | 16491 | 2452 |
PPP4R4,PPP1R12A,PPP1R2,CALM1,CALM3,SBF1,PPP1R14C,PPP2R3A,BMP2K,SH3RF2,BMP2,CALM2,PPP2R5A,PPP1R10,PPME1,PPP1R16A,PPP2R4,PPP4R1,RCAN2,CABIN1,RCAN3,PPP2R2D,PPP2R5D,DMPK |
| 1.842e-03 | -6.30 | actin cytoskeleton | cellular component | GO:0015629 | 445 | 88 | 17570 | 2579 |
MYL9,GAS2L1,SORBS1,NF2,ADD1,FAM129B,IQGAP1,MICALL2,FAM101B,APC2,SPTB,ZYX,SCNN1A,CDH1,CAPG,ESPN,MYH14,NOTCH3,CTTN,TLN2,MYRIP,FLOT2,NEB,MYO5B,TAF5,DMTN,DSTN,EZR,ANLN,MYOM1,MYL12A,STK17B,LCP1,ARHGAP35,DPYSL3,MPRIP,FYN,BFSP1,PDLIM3,CORO1C,MYLK,TRIOBP,SPTBN5,TMOD2,MYL12B,COBL,DDX58,BIN1,LASP1,FBLIM1,BMF,PPP1R12A,CIT,FLOT1,MYO5C,CORO1B,CAPN2,RAC2,VASP,RINL,LLGL2,CALD1,DAPK1,ACTA2,KNTC1,C9orf72,MYO5A,POU6F1,PGM1,ADAM17,CASK,FMN1,CORO2A,FHL2,PLS1,YES1,AIF1L,ILK,BCAR1,ABLIM2,KLHL2,DCTN6,TSC1,PLEKHH2,H1F0,PKD2,ARPC2,SHROOM2 |
| 1.847e-03 | -6.29 | KEGG_PANCREATIC_CANCER | MSigDB lists | KEGG_PANCREATIC_CANCER | 70 | 20 | 17758 | 2588 |
AKT1,RALBP1,CASP9,PIK3R1,TP53,ERBB2,TGFBR1,BCL2L1,EGFR,PGF,CCND1,RB1,RAC2,JAK1,RALB,STAT1,E2F1,PIK3CA,PIK3CD,PLD1 |
| 1.847e-03 | -6.29 | GNF2_TAL1 | MSigDB lists | GNF2_TAL1 | 70 | 20 | 17758 | 2588 |
TMCC2,GCLM,ERMAP,HEBP1,MPP1,BLVRB,BNIP3L,UBAC1,EIF2AK1,SPTB,BMP2K,RAD23A,FECH,MARCH8,ANK1,CA2,H1F0,FBXO7,MINPP1,TRAK2 |
| 1.847e-03 | -6.29 | PID_CDC42_PATHWAY | MSigDB lists | PID_CDC42_PATHWAY | 70 | 20 | 17758 | 2588 |
RASGRF1,PAX6,IQGAP1,ARHGEF7,EPS8,PIK3R1,YES1,CBL,BCAR1,CDH1,CTNNB1,LIMK1,PAK2,DLG1,PIK3CA,MAP3K11,PLD1,IQGAP3,ARPC2,TIAM1 |
| 1.847e-03 | -6.29 | PROTEIN_DIMERIZATION_ACTIVITY | MSigDB lists | PROTEIN_DIMERIZATION_ACTIVITY | 179 | 41 | 17758 | 2588 |
S100A11,HEXB,ABCG4,TAP1,ABCG2,TP53,ERBB2,BARD1,SLC9A7,TOP2A,FOXP2,CARD8,CST3,MAP3K9,BAX,TFAP2A,MSH2,ARNT2,ERBB3,S100A6,CCDC88A,MSH6,SMC4,CLCN3,TAF5,CDA,BNIP3L,CR2,TFAP2C,EIF2AK1,EGFR,PVRL2,TBX1,PPP2R4,KIAA1804,MAP3K11,GLA,ANXA9,MAP3K5,NRBP1,ABCG1 |
| 1.848e-03 | -6.29 | MYC_UP.V1_DN | MSigDB lists | MYC_UP.V1_DN | 152 | 36 | 17758 | 2588 |
LMTK3,CDCA8,PBX3,IL18,SAMD9,PJA2,C11orf95,HOXB2,SPTB,C16orf74,CPNE2,GRHL1,LYPD3,CDKL5,CCDC82,MTMR11,PTPRE,CLIP2,REC8,KRT80,PLK1,ATL1,KIAA1841,B9D2,BCL9,TEP1,FAM73B,BCAR1,MAP3K6,SPNS3,IL1R1,KLF12,ATXN7L3,FGD6,FBXO27,SERPINB1 |
| 1.849e-03 | -6.29 | REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 14 | 7 | 17758 | 2588 |
FGD6,TSC1,ARAP3,ARF6,RALBP1,ARAP1,FGD1 |
| 1.849e-03 | -6.29 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE | 14 | 7 | 17758 | 2588 |
B3GNT7,B3GNT2,B4GALT4,B4GALT3,ST3GAL1,CHST2,FUT8 |
| 1.849e-03 | -6.29 | MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP | MSigDB lists | MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP | 14 | 7 | 17758 | 2588 |
CD99,AES,CCNF,CITED2,PAFAH1B3,PPP2R5D,DNM2 |
| 1.849e-03 | -6.29 | MODULE_194 | MSigDB lists | MODULE_194 | 14 | 7 | 17758 | 2588 |
ALDH3B1,ALDH7A1,ALDH5A1,ALDH6A1,ALDH3A2,ALDH1A3,AOX1 |
| 1.861e-03 | -6.29 | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP | 190 | 43 | 17758 | 2588 |
CCDC109B,FRMD4A,SERPINE2,TMTC3,FRMD6,CCNO,RNF182,GMCL1,TGFBR1,OSR2,RB1,WEE1,RGS12,IGF1R,GNB5,KIAA1107,SPIN4,TSPAN6,NTN4,PACSIN1,DLG3,SLC12A2,TIAM1,FAR1,ZNF365,CPD,GCA,CRIP2,MBNL3,VEZT,GGH,COL7A1,RAB3IP,DHDH,SWAP70,KCNMB4,PRKAG2,FAM110C,TBC1D4,HOOK1,CYBRD1,XDH,RRAGD |
| 1.861e-03 | -6.29 | GSE14350_IL2RB_KO_VS_WT_TEFF_DN | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TEFF_DN | 190 | 43 | 17758 | 2588 |
CCNC,SLC2A4,HSP90B1,ARMCX3,EPAS1,PDIA5,TEX2,TP53I11,TMEM170B,CRABP2,ETS1,ARHGEF16,APOBEC3B,MLPH,UBE2T,MGAT1,ELMO2,TACC2,SLC16A6,KCNK5,GALNS,PRC1,MANF,F2R,GFI1,NEB,GCLC,CORO2A,CDYL,EZR,KIAA1109,RUNX3,TXNDC11,ALCAM,G2E3,LRRC42,PELI2,NXPH4,PLXND1,HMGA1,CMPK2,SHROOM2,HOXC13 |
| 1.861e-03 | -6.29 | GSE3982_MAST_CELL_VS_NKCELL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_DN | 190 | 43 | 17758 | 2588 |
SIGIRR,CDS2,NUAK1,GRIK2,HLA-F,CACNA2D2,ABCG2,IL27RA,PIGL,BARD1,HDAC9,CAPN2,GALNS,REEP1,ATRNL1,CADPS2,OAS3,TSPAN1,F2R,ETV4,SUN2,VPS11,ASXL1,SEPT6,STAT4,SYNE2,PPARA,EIF2AK1,NDRG3,GINS4,PDE11A,TXK,ARHGAP24,GABRD,FYN,DOLPP1,TMC5,SECTM1,ARAP1,NRG1,SPTBN5,UNC5B,RUSC1 |
| 1.861e-03 | -6.29 | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDM_UP | 190 | 43 | 17758 | 2588 |
ELK4,SPRED1,LGALS3,C6orf106,PSMD10,FBXO6,CMTM6,FANCI,TMCC3,RASSF8,WDFY1,CST3,RRBP1,TMEM51,H2AFY,SGK1,IRF2,TMBIM6,MDFIC,TSPAN13,SGCB,TIPARP,RBMS2,SCN3A,DUSP1,P2RX4,DPYSL5,SUN2,SLC37A1,PLSCR1,ITCH,PLEKHO1,SAT1,UTRN,RNF19B,NCOA3,STAT6,ABCB1,RGS14,NRBP1,ANXA11,ATMIN,JARID2 |
| 1.861e-03 | -6.29 | GSE14350_IL2RB_KO_VS_WT_TREG_UP | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TREG_UP | 190 | 43 | 17758 | 2588 |
TPRN,GOLIM4,ARL4C,EFHD2,DSE,DPP8,DENND2D,WDFY1,ST5,EFR3A,FAM160A2,MGAT4A,MITF,FAM102A,MDFIC,NFU1,RCAN3,ALS2CL,SLC16A5,DDX59,OSGIN1,CTH,MBP,SLC37A1,BCL9,PTPN9,BTBD19,PRKCQ,NPC2,ITPR3,TRUB1,NFIX,PDE11A,TAPBP,NT5C2,FASTKD1,PHLPP2,STAT1,TRIOBP,NLRC5,RHOBTB2,CANT1,ARSB |
| 1.861e-03 | -6.29 | CAIRO_HEPATOBLASTOMA_UP | MSigDB lists | CAIRO_HEPATOBLASTOMA_UP | 201 | 45 | 17758 | 2588 |
BCAM,PPP1R2,SERPINE2,MPZL1,ITGA6,TP53,PSMD10,RACGAP1,TRIB2,C11orf95,SAC3D1,SLC25A36,EPCAM,CD46,PDGFA,MARCH8,GPC3,DDHD2,PAPSS1,DRAM1,TAX1BP3,MINPP1,HSPA2,CKAP4,SEPHS1,SOCS5,CPD,MLEC,TACC1,ADCK3,RC3H2,CBX6,UTRN,LRRC1,ALCAM,DCP2,MAGED2,NCOA3,WFS1,CLMN,PDXK,NUP37,HSPB1,CBX5,JARID2 |
| 1.867e-03 | -6.28 | V$FREAC2_01 | MSigDB lists | V$FREAC2_01 | 240 | 52 | 17758 | 2588 |
RMND5A,SLC2A4,CDKN1C,CHCHD7,THRA,NDRG1,ETV5,HABP4,DHX8,PHLPP1,SEPP1,DHRS3,ZNF385B,MECOM,CD109,TFAP4,BMP2,FOXP2,WEE1,SNX13,KCTD15,FRY,CALD1,IL6ST,LMO4,MITF,KLF3,CITED2,CLIP2,TIAM1,PLCB2,DUSP1,CXXC5,BCL9,DSTN,RGAG1,ROR1,DUSP4,NFIB,NFIX,PITX2,KLF12,PELI2,KBTBD2,AXL,NRG1,C1orf43,TOB1,MAFF,RAD21,NGEF,EGLN1 |
| 1.869e-03 | -6.28 | PTB | smart domains | SM00462 | 31 | 12 | 9131 | 1455 |
TNS3,LDLRAP1,RGS12,TBC1D1,SHC3,ANKS1B,EPS8,TNS1,APBA1,APBA2,TBC1D4,MAPK8IP1 |
| 1.872e-03 | -6.28 | negative regulation of cell differentiation | biological process | GO:0045596 | 590 | 114 | 16441 | 2455 |
GAS2L1,PAX6,GRHL2,INPP5D,SUZ12,EPHA4,TP53,PKP2,GATA3,ERBB2,IL18,FLT3,FAM101B,TP73,CCND1,NOV,CTNNB1,ELF5,BCL6,SMO,DUSP10,TNPO2,DAB2IP,TWIST1,TACSTD2,DIXDC1,SEMA3G,NOTCH3,SEMA3B,SIRT1,ASXL1,DMTN,ULK2,FZD7,IRX3,DPYSL3,ENPP1,AREG,PLK2,CORO1C,TBX1,HOXA9,WWTR1,INPP4B,STAT1,HDAC1,NRG1,RAB29,ARF6,ABCA1,CTDSP1,SEMA6B,SORT1,ADGRG1,CIT,UBASH3B,SOX9,LRP4,TGFBR1,TRIB2,FBLN1,SIX4,BMP2,CALR,SPP1,PTEN,GATA2,BMP7,BHLHE41,VASN,FBXO7,KIAA0319,SORL1,NTN1,WNT3A,GFI1,ITM2C,TTPA,TRIM62,SOCS5,HES1,RHOA,WNT10B,MFI2,ASPM,RAPGEF2,PIK3R1,PPARA,MBNL3,PRICKLE1,NPHP3,CDK5R1,NCOA3,AP1AR,TWSG1,SEMA4D,ACVRL1,NFKBIA,E2F1,ITGAV,GPER1,GDF11,EFNA1,SOX8,OSR1,JAK3,SEMA3A,TOB1,RARG,FOXA1,ABCG1,XDH,NGEF,IRF1 |
| 1.873e-03 | -6.28 | cytoskeleton-dependent cytokinesis | biological process | GO:0061640 | 37 | 13 | 16441 | 2455 |
PLK1,RHOA,KIF20A,SNX18,CKAP2,KIF23,NUSAP1,RACGAP1,AURKB,CNTROB,ANLN,SNX9,RASA1 |
| 1.876e-03 | -6.28 | SPTLC2 (serine palmitoyltransferase, long chain base subunit 2) | protein interactions | 9517 | 10 | 6 | 16036 | 2547 |
P2RX4,NRG1,NOTCH3,FAM189A2,SPINT2,BCL6 |
| 1.876e-03 | -6.28 | IL1A (interleukin 1 alpha) | protein interactions | 3552 | 10 | 6 | 16036 | 2547 |
IL1R1,NFKBIE,S100A13,IL1RAP,CAPN1,TP53 |
| 1.876e-03 | -6.28 | ABCA3 (ATP binding cassette subfamily A member 3) | protein interactions | 21 | 10 | 6 | 16036 | 2547 |
NRG1,ATP1B3,FAM189A2,HLA-E,SPINT2,MCOLN3 |
| 1.879e-03 | -6.28 | SAM/pointed | interpro domains | IPR013761 | 115 | 29 | 18293 | 2672 |
ARAP3,ARAP2,INPPL1,EPHA4,PPFIBP2,SAMD9,EPHA1,ETS1,MAP3K6,SCML1,ELF3,EPHA10,TP73,DGKH,GAREM2,ANKS6,ETS2,ANKS1B,STIM1,DDHD2,ELF5,ARAP1,SFMBT1,SAMD8,EPHB4,MAP3K5,ETV7,STARD13,PHC1 |
| 1.889e-03 | -6.27 | REACTOME_SIGNALING_BY_ILS | MSigDB lists | REACTOME_SIGNALING_BY_ILS | 105 | 27 | 17758 | 2588 |
MAP3K3,INPPL1,RIPK2,TAB3,PIK3R1,CUL1,IL18,PELI3,YES1,CBL,CDK1,SOCS3,IL1R1,FYN,JAK1,IRAK1,IL6ST,PELI2,STAT1,NOD2,PIK3CA,PIK3CD,MAP3K7,NFKB2,JAK3,SYK,IL1RAP |
| 1.891e-03 | -6.27 | toll-like receptor signaling pathway | biological process | GO:0002224 | 128 | 32 | 16441 | 2455 |
UNC93B1,HSP90B1,TAB3,CTSB,RPS6KA1,CUL1,RPS6KA2,IRAK1,PIK3AP1,MAPK11,MAP3K7,SCARA3,NFKB2,LGMN,MAPK7,CNPY3,TNIP1,RIPK2,MAPKAPK3,ELK1,DUSP4,FOS,BCL10,MAPKAPK2,CTSL,PELI2,NFKBIA,NOD2,UBE2D2,IRF7,PPP2R5D,RPS6KA3 |
| 1.896e-03 | -6.27 | CELL_DEVELOPMENT | MSigDB lists | CELL_DEVELOPMENT | 568 | 108 | 17758 | 2588 |
CASP3,ACVR1,NF2,AGRN,GRIK2,XIAP,TP53,CUL1,BCL2L1,AIFM2,BARD1,TNFSF9,PICK1,IER3,TP73,DAPK2,CDKN2C,ARTN,CTNNB1,SIVA1,BCL6,CDKN1B,TNFRSF18,F2R,CDKN2D,HSPA2,SEMA3B,MX1,BAG4,SOD1,AKT1,ACVR1C,S100A4,CASP9,BNIP3L,HTATIP2,GLO1,STK17B,CDK1,CASP4,VCP,OPTN,SOCS3,RTN4RL1,DNM1L,MADD,STAT1,HDAC1,AIFM3,HSPB1,CBX4,MAPK12,BMF,HSP90B1,DAP,CTSB,CIT,BIK,SERPINB9,RACGAP1,NOTCH2,NCKAP1,GSTP1,ADAMTSL4,NRP2,RND1,SGPL1,BMP2,CALR,TOP2A,CARD8,ADORA1,IGF1R,PTEN,BMP7,BAX,DAPK1,CD70,ERCC2,PIM1,NPTN,RAG1,TMX1,FARP2,DPYSL5,GCLC,PARP4,RUNX3,CYFIP2,BCAR1,RASA1,CDK5R1,RHOB,FAS,BCL10,STK17A,BTG1,CASP7,SCG2,HTT,SEMA4D,NFKBIA,E2F1,MAP3K5,IFI6,HIPK3,ESPL1,AHR |
| 1.898e-03 | -6.27 | CELL_SURFACE | MSigDB lists | CELL_SURFACE | 75 | 21 | 17758 | 2588 |
BCAM,SLC2A4,PLAUR,RC3H2,NOTCH2,M6PR,SRPX,P4HB,ALPP,FGFR2,ACVRL1,PGRMC1,MPP2,ABCB1,TMEM8B,EPHB4,ANXA9,HSPB1,FLOT2,HSPA2,SULF2 |
| 1.898e-03 | -6.27 | JACKSON_DNMT1_TARGETS_UP | MSigDB lists | JACKSON_DNMT1_TARGETS_UP | 75 | 21 | 17758 | 2588 |
BIN1,MX1,IGFBP6,IFIT3,PHLDA1,SOCS3,PDGFA,PTGS2,CTNNB1,CYR61,GATA2,ZFP36,CSF1,AHCY,IRF7,IFIT1,HMGA1,ETV4,HSPB1,IL10RB,IL1RAP |
| 1.898e-03 | -6.27 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION | MSigDB lists | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION | 75 | 21 | 17758 | 2588 |
RIPK2,MAPKAPK3,TAB3,RPS6KA1,PELI3,DUSP4,ELK1,FOS,CDK1,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 1.910e-03 | -6.26 | YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon) | protein interactions | 7531 | 364 | 79 | 16036 | 2547 |
LMO7,CASP3,TNK1,TUBB4B,KLC2,TP53,PKP2,CUL1,FTH1,PCBP1,CDK14,C11orf84,RGS3,OSBPL3,REEP1,CDKN1B,TIAM1,MAP3K3,ING1,AKT1,PFKFB2,DMTN,KIF1C,MCFD2,SAV1,CBL,CDC25C,VCP,IRS2,STK26,NGFRAP1,WWTR1,RAB11FIP1,HSPB1,PSMC1,ISOC1,CBX4,PPP1R2,TBC1D1,DCAF7,PRKAA1,KIF23,FBXO6,HDAC9,PDIA4,RASSF8,KIF5B,CAPN2,CALR,TOP2A,VASP,IGF1R,CDK16,PAK2,CFAP43,FAM13B,KLC3,PRKCI,ACTA2,ALDH7A1,MAP3K7,MAPK7,RPGR,RASGRF1,ARHGEF28,CALM1,CAPNS1,BCAR1,TSC1,RAB11FIP2,DCUN1D1,SH3BP4,ARRB1,CDK18,CENPE,MAP3K5,TBC1D4,SHROOM2,USP43 |
| 1.911e-03 | -6.26 | collagen metabolic process | biological process | GO:0032963 | 83 | 23 | 16441 | 2455 |
COL9A3,ADAMTS2,MRC2,ADAM17,COL6A2,CTSB,P3H2,FURIN,P2RX7,COL18A1,KLK6,COL4A5,COL7A1,COL12A1,CTSL,MMP15,TRAM2,COL13A1,COL6A1,ADAM15,ADAMTS14,CTSD,COL16A1 |
| 1.915e-03 | -6.26 | BENPORATH_NANOG_TARGETS | MSigDB lists | BENPORATH_NANOG_TARGETS | 942 | 169 | 17758 | 2588 |
EXPH5,PNISR,TRIM24,CNOT8,LMCD1,F11R,MORF4L2,ISOC2,PIGL,KIF26A,MAP1LC3B,WEE1,RAB15,PCNA,CTGF,UBE2T,METTL7A,DPYSL2,TSPAN6,CYP2S1,SLC44A1,PSMC2,POLL,DNM2,TUBG1,TIAM1,ODF2L,CYP1B1,ING1,ASXL1,FOPNL,CASP9,CDYL,KDELR3,ROR1,SAV1,ICMT,ADRBK2,CDK1,COL12A1,ARF4,DPYSL3,GDE1,GNPTAB,MAP3K11,PRKCDBP,GLA,PRSS8,CDK17,PPP1R2,GGA1,TMEM55B,ADO,PDCL,ASAH1,SLC36A4,DHRS3,FBLN1,BMP2,CALR,TYW3,CA2,CYR61,FAM20C,ZNRF2,FBXL14,MSH2,FXYD5,TNFRSF12A,SLAIN2,KNTC1,UFD1L,MICB,EPHA1,KDM3A,RASA1,CACHD1,NT5C2,C1orf21,AURKA,MDH1,CBX5,KLF7,GAS2L1,PLEKHG3,ARHGAP11A,SPRED1,MTM1,SORBS1,FAM92A1,DLGAP5,GRHL2,PAPSS2,S100A11,TRIP10,ETNK1,WDTC1,ERBB2,BLCAP,PCBP1,RAD23A,CDK14,APLP2,KCTD15,SCNN1A,CDH1,ACSL4,EGLN3,DVL2,TBC1D10B,CKS2,TMEM43,SEPT6,FOXJ2,NUSAP1,DNAJB14,PKMYT1,RAB38,KCTD2,ALCAM,FZD7,PEX2,KLF5,ZNF701,IER5L,CDS2,GOLIM4,SDC4,COL4A5,SEPP1,IFT27,NFAT5,PPP2R3A,TMEM63A,AKIRIN1,TOP2A,MZT2A,ADD3,CDK16,BMP7,CALD1,SGK3,SGK1,IGFBP2,AK3,HEXIM2,CITED2,FAM134C,IGDCC4,NFE2L3,PSMB4,BCL9,AK4,COL7A1,TCEAL8,MPV17L2,DDX23,PITX2,SERPINA1,FGFR2,PRCP,HNRNPH2,PPP2R3C,ACADM,WDR62,OSR1,SAT2,JARID2,USP16 |
| 1.918e-03 | -6.26 | HALLMARK_ANDROGEN_RESPONSE | MSigDB lists | HALLMARK_ANDROGEN_RESPONSE | 100 | 26 | 17758 | 2588 |
ELK4,NKX3-1,AKT1,NDRG1,SAT1,SEPP1,MERTK,CENPN,MYL12A,APPBP2,DNAJB9,CCND1,UAP1,H1F0,ALDH1A3,DBI,INPP4B,UBE2J1,SGK1,STK39,SPCS3,ITGAV,ZMIZ1,LMAN1,LIFR,RPS6KA3 |
| 1.928e-03 | -6.25 | MODULE_98 | MSigDB lists | MODULE_98 | 384 | 77 | 17758 | 2588 |
CCNE2,PAX6,FOXM1,PTTG1,NDC80,CCNO,KIF2C,CCNB1,BARD1,PHLDA1,PCBP1,RAD23A,CDKN2C,WEE1,APLP2,PCNA,CCNA2,HSF2,KIF22,MYT1,PLK1,NEK4,TAF5,CENPA,AKT1,GTF2A2,CDC25C,CDK1,PRIM1,MAP2,STK38,STAT1,HDAC1,TLE1,XRCC3,PPP2R5D,CBX4,SOX9,PSMD10,KIF23,DUSP5,H1FX,TOP2A,ZFX,MSH2,NEK2,GTF2F2,TFAP2A,BUB1,KNTC1,RFX5,CITED2,GFI1,PSMA5,TGIF1,ZWINT,MAPKAPK3,PAPD7,BCL9,MYBL2,UBE2A,RUNX3,FXR2,FOS,PSMA4,DDX23,FOXD2,HNRNPH2,DCK,E2F1,CSTF2,CENPE,CCNB2,CBX5,ESPL1,CSRP2,RAD21 |
| 1.930e-03 | -6.25 | nuclear membrane part | cellular component | GO:0044453 | 14 | 7 | 17570 | 2579 |
LEMD2,SUN1,P2RX4,P2RX7,SUN2,TMEM43,LBR |
| 1.935e-03 | -6.25 | mediastinum | COSMIC cancer mutations | mediastinum | 38 | 13 | 17775 | 2585 |
CDKN2C,CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,JAK3,EGFR |
| 1.936e-03 | -6.25 | cellular component disassembly involved in execution phase of apoptosis | biological process | GO:0006921 | 64 | 19 | 16441 | 2455 |
CASP3,ADD1,ACVR1C,SHARPIN,BLCAP,PRKCQ,BCAP31,LMNA,TOP2A,FNTA,CASP7,CDH1,CTNNB1,STK26,DNM1L,H1F0,PAK2,GPER1,OCLN |
| 1.938e-03 | -6.25 | MODULE_57 | MSigDB lists | MODULE_57 | 56 | 17 | 17758 | 2588 |
CCNE2,PLK1,PTTG1,CDC20,TP53,PKMYT1,CCNB1,CDC25C,CDK1,WEE1,CCNA2,PCNA,E2F1,HDAC1,BUB1,CCNB2,ESPL1 |
| 1.938e-03 | -6.25 | REACTOME_REGULATION_OF_APOPTOSIS | MSigDB lists | REACTOME_REGULATION_OF_APOPTOSIS | 56 | 17 | 17758 | 2588 |
CASP3,PSMB4,PSME2,CASP9,PSMD7,PSMD10,PSME1,PSMA4,DAPK2,PSMD1,PSMD3,PSMC2,PAK2,DAPK1,UNC5B,PSMC1,PSMA5 |
| 1.939e-03 | -6.25 | hemopoiesis | biological process | GO:0030097 | 520 | 102 | 16441 | 2455 |
CASP3,ADD1,HOXB7,EPAS1,IL15,LFNG,THRA,TP53,GATA3,FLT3,PDGFB,TNFSF9,SPTB,TGFBR3,CTNNB1,PLCG2,MITF,IL31RA,TMEM143,BCL6,RTKN2,ASH2L,PIK3CD,SNX10,TIPARP,LGALS8,OSTM1,DMTN,CASP9,NFE2L1,PTGER4,CR2,SLC11A2,GLO1,PYGO1,ANLN,FZD7,CMTM7,SFXN1,STAT6,HOXA9,AXL,PTBP3,DHTKD1,RPL22,F2RL1,KLF2,DYRK3,RUNX2,TNRC6C,CDKN1C,BVES,ARHGEF7,JAG2,NOTCH2,HERC6,MERTK,IL18R1,HDAC9,MECOM,SGPL1,TOP2A,CD109,RB1,FAM20C,GATA2,GPC3,BAX,MSH2,FNIP1,ERCC2,RAG1,WNT3A,GFI1,SYK,FARP2,ADAM17,RHOA,WNT10B,CRIP2,RC3H2,PIK3R1,TTC7A,RUNX3,EIF2AK1,TXK,FAS,FECH,CD8A,ONECUT1,TSC1,FGFR2,TWSG1,PRDX3,DHRS2,CSF1,LRRK1,FZD5,JAK3,SLC25A38,MELK,IRF1 |
| 1.939e-03 | -6.25 | epiboly | biological process | GO:0090504 | 21 | 9 | 16441 | 2455 |
ARHGAP24,ADAM17,RHOA,PDCD10,CYR61,ACVRL1,MEGF8,DDR1,LCP1 |
| 1.939e-03 | -6.25 | glucan catabolic process | biological process | GO:0009251 | 21 | 9 | 16441 | 2455 |
CALM2,PGM1,GAA,CALM1,MGAM,PYGL,CALM3,PHKA2,PHKG2 |
| 1.939e-03 | -6.25 | cellular polysaccharide catabolic process | biological process | GO:0044247 | 21 | 9 | 16441 | 2455 |
CALM2,PGM1,GAA,CALM1,MGAM,PYGL,CALM3,PHKA2,PHKG2 |
| 1.939e-03 | -6.25 | lipid translocation | biological process | GO:0034204 | 21 | 9 | 16441 | 2455 |
KCNN4,ATP8A1,ATP9A,TMEM30A,P2RX7,ATP8B1,ATP8B3,ABCA1,ATP10D |
| 1.946e-03 | -6.24 | PYEON_HPV_POSITIVE_TUMORS_UP | MSigDB lists | PYEON_HPV_POSITIVE_TUMORS_UP | 85 | 23 | 17758 | 2588 |
ZMAT1,SMARCA2,PNISR,KIAA1841,BTNL9,NEURL1B,BARD1,PDIK1L,PSIP1,IL17RB,CDKN2C,E2F7,NR1D2,CENPJ,ZNF367,USP1,DONSON,RTKN2,KNTC1,PER3,GEN1,SYK,MPHOSPH9 |
| 1.946e-03 | -6.24 | TIEN_INTESTINE_PROBIOTICS_2HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_2HR_DN | 85 | 23 | 17758 | 2588 |
SEC23A,RECQL,MMD,RAPGEF2,ETNK1,GGH,PLXNA1,PDHX,STX3,ZFYVE16,TNS3,PTGS2,ALDH5A1,PRCP,FLRT3,CALD1,PPP4R1,WWTR1,TCEAL4,HSPA13,ARMCX6,E2F8,CKAP4 |
| 1.951e-03 | -6.24 | ureteric bud development | biological process | GO:0001657 | 88 | 24 | 16441 | 2455 |
HES1,FMN1,RET,SOX9,DCHS1,SDC4,GATA3,ILK,SDC1,EPCAM,BMP2,CTNNBIP1,FAT4,CTNNB1,FGFR2,NPNT,GPC3,BMP7,DLG1,PKD2,TACSTD2,GDF11,OSR1,ADAMTS16 |
| 1.951e-03 | -6.24 | nephron development | biological process | GO:0072006 | 118 | 30 | 16441 | 2455 |
HES1,LGR4,FMN1,IQGAP1,SOX9,DCHS1,GATA3,ILK,PDGFB,IRX3,BMP2,CTNNBIP1,PROM1,ITGA3,FAT4,CTNNB1,NPNT,GPC3,BMP7,WWTR1,DLG1,SMO,ACTA2,PKD2,TACSTD2,NOTCH3,OSR1,SOX8,SULF2,ADAMTS16 |
| 1.955e-03 | -6.24 | DAZARD_RESPONSE_TO_UV_NHEK_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_DN | 303 | 63 | 17758 | 2588 |
EXPH5,MTM1,PNISR,PPP1R12A,ARHGEF7,GNE,TMX4,KIF23,CUL1,PHLPP1,CCNB1,HMGXB4,APPBP2,PER2,SLC25A36,TOP2A,WEE1,FRYL,KIF14,ATP13A3,PLK4,USP1,KLF9,ERBB3,PIKFYVE,BTBD3,TIPARP,MAST4,NCOA2,MSH6,ATP2B1,SMC4,DOCK4,CENPA,NR3C1,PAPD7,ASXL1,GCLC,MICB,RAPGEF2,CDYL,FNDC3A,POLD3,KIF11,USP6,BCAR3,LRRC42,CNOT2,NCOA3,FYN,SERTAD2,FGFR2,SLC9A6,KBTBD2,AURKA,TTC9,MAP3K5,ZMIZ1,CCNB2,AHR,KLF7,JARID2,DOCK9 |
| 1.959e-03 | -6.24 | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP | 185 | 42 | 17758 | 2588 |
PARP12,GNPDA1,ATP8A1,ARHGEF7,INPP5D,TMX4,ARL4C,DGKA,PBX3,NKRF,TNFSF9,EXT2,ABCD4,SLC25A36,PLS3,CCDC92,RNF220,HSF2,CNTRL,CD22,CAPG,ASH2L,PIKFYVE,SNX10,SCN3A,MCCC2,PTPN18,ADCK3,AMFR,RUNX3,NDRG3,KLHL2,ARHGAP24,KBTBD2,WDR19,RAP2C,TDRD7,SPAG7,RAB11FIP1,VSIG10,WDR91,JARID2 |
| 1.959e-03 | -6.24 | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | 185 | 42 | 17758 | 2588 |
LGALS3,CKAP2,SLC25A13,BIK,TIPRL,PGAP1,HMGXB4,TTC21B,KIF5B,RBM23,VASP,PPP1R10,IL6ST,LMO4,ALG13,PRC1,DNM2,KLF9,ETHE1,SPRY2,PPIF,PLK1,CD55,SEPT6,DENND1B,BNIP3L,MYBL2,EZR,CR2,NUSAP1,ASB13,RNF19B,BCAR3,BTG1,NR1D2,CABIN1,LRRK1,GLA,MAP3K5,PLIN3,MAFF,JARID2 |
| 1.963e-03 | -6.23 | PLASARI_TGFB1_TARGETS_10HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_UP | 196 | 44 | 17758 | 2588 |
PLEKHG3,NUDT6,PAPSS2,NUAK1,NES,TGFBR1,LPIN3,SLC20A1,PDGFB,DUSP5,CARD10,TMCC3,IER3,PDGFA,CTGF,ALDH1A3,FJX1,CNNM4,TNFRSF12A,HSPA2,ALS2CL,CTH,PDGFC,PLAUR,SPATA13,DUSP4,CD40,RNF19B,ZNF469,CRISPLD2,ENDOD1,GALNT3,PTGS2,PI4K2B,ENPP1,TIMP3,KCNK1,MFSD2A,FGF18,ABCB1,TTC9,UNC5B,F2RL1,MAFF |
| 1.963e-03 | -6.23 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP | 196 | 44 | 17758 | 2588 |
KIF3C,AGRN,PAPSS2,NQO1,ATP9A,TRAF2,FAM134A,PPFIBP2,PHF1,SGPL1,AKIRIN1,CALR,ST5,CA2,RALGPS2,CNTRL,COL6A1,BCL6,ABCD1,NAGA,MX1,COL6A2,TIMP2,CTNNAL1,SPA17,MEST,TCN2,SP4,ULK2,BSDC1,SOX13,NCOA3,RPL12,COQ10A,ACVRL1,NR4A3,CANT1,ARFGAP3,TMEM159,RPL22,F2RL1,USF2,JARID2,ABCG1 |
| 1.963e-03 | -6.23 | GSE339_CD4POS_VS_CD8POS_DC_UP | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_UP | 196 | 44 | 17758 | 2588 |
BIN1,LASP1,ARHGEF3,TCF25,NLRX1,ARL4C,ETNK1,DHRS3,TNFRSF19,MNS1,LBR,B4GALNT1,RAC2,RGS3,FAM13B,DLG1,ABCA2,NDUFA12,GCNT1,MAP3K3,SMARCA2,RHOA,NR4A1,USP18,TEP1,EMP3,FBXO8,GGH,CCNF,SESN1,ULK2,SOX13,BCL10,IL1R1,PTGS2,COL13A1,STK38,ABCB1,CTSA,SERPINI1,PLXND1,RGS14,LTA4H,PPP2R5D |
| 1.964e-03 | -6.23 | response to abiotic stimulus | biological process | GO:0009628 | 1116 | 201 | 16441 | 2455 |
CASP3,TXN,AGRN,HSPG2,EPAS1,TSC22D3,DNAJC3,CUL4B,GATA3,F11R,ITPR2,CCNB1,HDAC6,CACNB4,PDGFB,SDC1,TMC1,PICK1,TP73,CALM2,CYP1A1,PCNA,TGFBR3,NUP210,CTGF,P4HB,FOSB,DNM2,AKR1B1,CRY2,PPP1CA,ARNT2,SCARA3,S100A13,METAP2,SOD1,PBK,CASP9,SPRTN,LOXL2,AURKB,VCP,PLEKHB1,KDM4D,EDNRA,MYLK,CAB39,SERPINB6,MAPK13,PIEZO1,SERPINE2,SOX9,PRKAA1,CALM3,SLC1A3,CNTNAP2,DHRS3,PSIP1,ANO1,LMNA,BMP2,CA2,VASN,MSH2,OPN3,AHCY,BRAT1,USP1,CNGA1,SLC12A2,NUP85,EEF1D,HP1BP3,DDB2,MICB,CALM1,ERO1A,PDK3,ELK1,GNA11,RHOB,EGFR,NMT2,FAS,FECH,MAPKAPK2,IL1R1,FNTA,HTT,NFKBIA,ITPR1,NR4A2,STK39,TRPC3,NUP58,DRD1,EGLN1,IRF1,DYNLRB1,SLC2A4,THRA,SLC2A8,NDRG1,XYLT1,TP53,P2RX7,GMPR,COL18A1,BCL2L1,SNN,SDF4,CDS1,CCND1,CDKN1B,TWIST1,LRP11,SCN2A,LGMN,EGLN3,CDKN2D,HSPA2,CHP1,SIRT1,BAG4,TCEB2,AKT1,FIGNL1,PTGER4,PRKCQ,SLC11A2,ATP1B1,TANC1,CD40,SOCS3,PTGS2,FYN,ATP1A1,ABHD12,PPP1CB,SLC27A1,XRCC3,RGS14,ARNT,DENND5B,PINK1,HSP90B1,NKX3-1,CPEB4,CTSB,HABP4,SDC4,SWI5,SELL,PKN1,ETS1,NFAT5,ICAM1,CAPN2,ADORA1,IRAK1,GNB5,PTEN,BMP7,GPC3,CST3,TFAP2A,BAX,CD9,IGFBP2,ERCC2,CITED2,GFI1,TTPA,RPGR,CAMK2G,MSH6,DUSP1,PGM1,ADAM17,RHOA,GCLC,PIK3R1,GRIN1,UBE2A,PPARA,RGCC,FOS,BCL10,GPLD1,RGS9,TIMP3,CTNS,PLOD2,E2F1,UBE2D2,ARRB1,PKD2,ICOSLG,NUP37,ARSB,CPEB2 |
| 1.973e-03 | -6.23 | BIOCARTA_IL2RB_PATHWAY | MSigDB lists | BIOCARTA_IL2RB_PATHWAY | 38 | 13 | 17758 | 2588 |
JAK1,AKT1,NMI,PIK3R1,PIK3CA,E2F1,BCL2L1,CBL,JAK3,FOS,SYK,FAS,SOCS3 |
| 1.973e-03 | -6.23 | PROTEIN_KINASE_REGULATOR_ACTIVITY | MSigDB lists | PROTEIN_KINASE_REGULATOR_ACTIVITY | 38 | 13 | 17758 | 2588 |
CDKN2C,CDKN1C,DNAJC3,MADD,CDKN1B,PRKAR2B,HEXIM2,CDKN2D,MAPK8IP1,CDK5R1,PKIA,PRKAR1A,SOCS3 |
| 1.975e-03 | -6.23 | Class I MHC mediated antigen processing & presentation | REACTOME pathways | R-HSA-983169 | 267 | 58 | 8202 | 1235 |
MRC2,KLHL13,SEC61G,PSME2,HLA-E,HLA-F,TAP1,FBXO2,ASB9,PSMD7,UBE2Z,PSMD10,PDIA3,UBE2Q1,CUL1,RNF182,PSME1,FBXO6,PJA2,SPSB1,HLA-A,DTX3L,CALR,RNF220,PSMD1,UBE2Q2,PSMC2,UBE2J1,TRIM21,WWP1,HLA-C,PSMA5,ERAP2,SEC23A,SEC61B,PSMB4,TCEB2,ITCH,CDC20,UBE2A,ASB13,RNF19B,PSMA4,SOCS3,TRIM9,CTSL,HLA-B,TAPBP,TRIM69,PSMD3,CTSV,UBE2D2,ERAP1,FBXO44,ITGAV,FBXO27,UBE2C,PSMC1 |
| 1.978e-03 | -6.23 | mesonephros development | biological process | GO:0001823 | 93 | 25 | 16441 | 2455 |
HES1,FMN1,RET,SOX9,DCHS1,SDC4,GATA3,OSR2,ILK,SDC1,EPCAM,BMP2,CTNNBIP1,FAT4,CTNNB1,FGFR2,NPNT,GPC3,BMP7,DLG1,PKD2,TACSTD2,GDF11,OSR1,ADAMTS16 |
| 1.978e-03 | -6.23 | ATGTTAA,MIR-302C | MSigDB lists | ATGTTAA,MIR-302C | 235 | 51 | 17758 | 2588 |
ACVR1,PPP1R12A,SH3D19,ZCCHC24,DCAF7,WDTC1,IL13RA1,PCBP1,NFAT5,SSX2IP,NRP2,BMP2,SIPA1L2,DAZAP1,ADD3,ANKRD12,USP1,FAM84B,PDE4D,PTPRE,MYT1,BTBD3,GAD1,SLC35A1,SIRT1,PHF20L1,LCA5,FZD4,ACBD3,RNF11,PPARA,VEZT,SRSF5,CYFIP2,SP4,ABR,RHEB,NFIX,IRS2,FGFR2,CDK19,ZMYND19,AMMECR1,FAM117A,SAMD8,ZMIZ1,LIFR,NR3C2,TOB1,CPEB2,FOXA1 |
| 1.979e-03 | -6.23 | soft_tissue | COSMIC cancer mutations | soft_tissue | 6065 | 947 | 17775 | 2585 |
DOC2A,HECA,ACACB,ADD1,IBTK,GRIK2,AASS,TRIM5,SLC25A13,DNAJC3,HEXB,RET,FBXO2,NRG2,TRAPPC8,BAIAP3,SYTL4,CA8,KIF26A,CARD10,PHF1,LTBP3,EPDR1,CDKN2C,TP73,NPM2,ZYX,TGFBR3,DNAH6,CABP1,PAQR5,RDH14,ALDH1A3,KLF3,CRY2,TIAM1,IL10RB,MGAT5,ODF2L,APOBEC3G,ERAP2,DNAAF3,NEK4,NWD1,SPEF2,SMARCA2,TNIP1,CDA,LOXL2,PPP1R14C,MYOM1,PNKD,COL12A1,LCP1,PIAS3,ENPP1,PLCG1,GRID2IP,DNM1L,ANKRD6,ATP7B,MYLK,FAM114A1,NOD2,STARD13,PDPR,GAB1,ZNF720,SCN5A,ALDH6A1,CYP2J2,ITGA6,SOX9,RAB23,SLC36A4,ZNRF3,CCDC64B,MERTK,FAM21C,LMNA,MARCH8,FRY,FAM189A1,CD22,MEGF8,FLRT3,ZIC5,FBXO7,MAP3K9,CADPS2,USP1,ALPK1,STT3B,CNGA1,ZMYM1,MOXD1,PPP6R1,MCCC2,PAQR7,SLC37A1,STAT4,MYBL2,KIF20B,GNA11,IL1R1,NCOA3,ETS2,HTT,SEMA4D,ITPR1,OSMR,DYSF,DRP2,RPS6KA3,TMEM173,XDH,ADAMTS16,DOCK9,WDR63,MTM1,PAPSS2,LFNG,GALNT12,FAM131C,PTTG1,APOO,WDTC1,RGS20,PKP2,TESK2,GRK6,FAM91A1,APC2,TNFSF9,KIAA1147,ZNF385B,UHRF1BP1L,RCN1,MUC16,RNF220,CDH1,SH3BP1,RTKN2,MYT1,SCN3A,TMCC2,ENPP4,MX1,SNX8,CAMSAP3,COL6A2,ERMP1,RIPK2,AGPS,PTPN9,SYNE2,TANC1,GIGYF1,NFIX,CCNB3,CDK19,WFS1,CORO1C,SLC9A6,PLEKHG1,FAM149A,DMWD,CTHRC1,FARP1,HSP90B1,TAOK2,FAM189A2,PARP14,ESRP1,RASSF7,CCM2,NUCB2,PLPPR4,GSTP1,ETS1,SRPX2,BEX2,HOXB2,ICAM1,NEO1,CXCL16,ANK1,ADD3,PDCD10,ITGB8,IRAK1,ANKS1B,ARSG,GPC3,TUBGCP6,FDXR,FAM102A,TMBIM6,IGFBP2,NPTXR,RAG1,TPCN1,PARP9,AMOTL2,LCA5,CTNNAL1,FMN1,MFSD2B,PIK3R1,MRS2,PLEKHA7,MYEOV,PGBD1,EMP3,RAB3IP,SNTB1,ABLIM2,GALNT3,PROM1,LDLRAP1,PLOD2,ATXN7L3,CCDC6,RAB11FIP2,ACVRL1,ZFP30,SLC35B3,FAM3C,DBI,PPM1H,FBXO44,CENPE,ITGAV,FHL1,CD81,USF2,FOXA1,PHC1,TMEM131,BCAM,KIAA1462,AGRN,CUL4B,FHDC1,ARFGEF1,TEX2,NENF,GALM,ITPR2,NUP62CL,SPTB,TFAP2E,SUSD2,ENTPD4,NUP210,TM9SF2,CTNNB1,P4HB,SHC3,PSMC2,PAPSS1,SLC44A1,TMEM143,ABCA2,RGS5,ANO4,TLN2,TRAM1,NEB,CCDC38,ZNF462,THRB,MCTP1,PTPN18,MARK1,CD55,EZR,CR2,CCBL2,IDH1,CLCN2,DZIP1L,OPTN,KDM4D,IRX3,TNS4,PI4K2B,PLCH1,HS6ST1,KCNMB4,MAP2,P4HA2,HOXA9,ZNF367,RAB11FIP1,ARRDC1,KLF11,PIK3C2B,PIEZO1,TTC39C,EPB41L4A,TC2N,HS6ST3,PRSS8,USH1C,LGALS3,UBASH3B,ZCCHC24,RASA2,PDCL,HES2,CNTNAP2,DOCK11,FBLN1,RSAD1,PGAP1,ANO1,SSX2IP,MYO5C,CORO1B,TNS3,RB1,KIAA0895,DAZAP1,UBE2Q2,IGF1R,FRAS1,TBCD,SLC30A6,MDFIC,PIM1,PLCB2,ALDH3A2,CHSY3,DPYSL5,WDR72,USP31,CORO2A,MGAT4B,SPATA13,KBTBD8,SCRIB,TCF7,EIF2AK1,PRX,NMT2,RASGRP2,DHDH,FA2H,H1F0,COL13A1,PHLPP2,ITGA7,SLC2A6,NLRC5,LTBP2,ZDBF2,PLD1,CTBP1,RAD21,USP43,NF2,UPF3B,XYLT1,TP53,RHPN2,ERBB2,P2RX7,SLC7A2,C1orf116,CYP26A1,SYTL2,PER2,IER3,CDK14,PDGFA,SRPX,WDR44,TACC2,PLCG2,BCL6,PLK4,CDH3,GYS1,ESPN,NOTCH3,OAS3,MINPP1,SCN2A,FAR1,CPD,PPIF,CLCN3,TMTC1,AKT1,PTGER4,ACO1,ATP13A2,MYPOP,DNAJC10,ZNF628,DUOX1,PTPRJ,C19orf66,ABHD12,PTK7,STK38,ADAMTS14,MAOA,EFNA5,IRF7,ANXA9,ST3GAL1,LTA4H,ZC3HC1,COL9A3,DYRK3,PACSIN2,TM2D2,GOLIM4,CDH22,TRAPPC10,KLHL13,MACC1,RUSC2,CTSB,SCD5,GNAL,MCTP2,GNE,ERCC6L,GDF15,JAG2,CRABP2,DSE,LBR,SLC9A2,PPP2R3A,SH2D4A,FZD6,CD109,FOXP2,CEP97,MAGEE1,TFAP2A,FAM63A,IL17RA,SGK1,TSPAN13,BUB1,CAMK2G,GCNT1,LRRC24,IGDCC4,NFE2L3,P2RX4,HMMR,DLGAP1,FBLN5,MOSPD2,NR3C1,PLAUR,LITAF,PPARA,PRICKLE1,DPP9,MAML2,CAPNS1,COL7A1,FNDC3A,NPDC1,RNPEP,BBS2,TXNDC11,BCAR1,CNOT2,BANK1,SERPINA1,FAT4,TWSG1,SCG2,ZMYND19,NAT1,NETO2,E2F1,CLIP4,PPP2R3C,ICOSLG,TBC1D4,PTGES,ARHGEF4,GOLGB1,FAM171B,GAA,LGR4,HSPG2,SSH1,ATP8A1,TSC22D3,TAP1,PPFIBP2,GATA3,PLXNA1,SEPT4,VASH1,FAM101B,PICK1,SLC9A7,CYP1A1,RGS3,OSBPL3,AOX1,PIK3CA,KCNS3,POLL,ATRNL1,SNX16,HYLS1,MTMR11,TFG,RCAN3,SGCE,SPATA18,ACVR1C,CASP9,NBPF3,KIF13A,TNS1,CCNF,POR,ULK2,AHRR,KDSR,PLK2,GNPTAB,FAM110C,PRDM5,DHTKD1,MAPK13,TANC2,TRAF5,LZTS1,FGD1,DDX58,KLF2,INPPL1,FRMD4A,DHPS,TBC1D1,DGKQ,KIF23,NOTCH2,SLC1A3,APBA1,PDXDC1,KIAA1161,SH3RF2,MECOM,DOPEY2,RALGPS2,CYR61,ZNRF2,NECAB3,AIM1,BDH1,MSH2,OPN3,PRKG1,SORL1,CACNA1D,C8orf58,PIKFYVE,CTSD,KCTD3,RIMS2,TMED2,EEF1D,SOCS5,IGSF3,DNAI1,EPB41L5,GFPT1,SPATA20,PIGC,KCNJ12,FADS2,MFI2,PRSS23,ADCK3,MICB,AMER1,DCHS1,PYGL,WHSC1,ATP8B3,ANTXR1,FRMD4B,PDE11A,FAS,DGKH,AP1AR,SLCO4A1,PRKAG2,PLEKHH2,TJP3,FAM64A,FAAH,DCK,NAB2,FAM83D,AGBL5,PCDH19,CABIN1,PER3,PLIN3,MAP3K5,IFIH1,EHD1,PKD1L2,PLA2G4A,PLEKHG3,SPRED1,TCTN2,CAPN12,NLRX1,IQGAP1,DDIT4L,IRX4,KCTD12,RNF182,CD274,FLT3,CYP39A1,ZFYVE9,EPS8L2,EPM2A,APLP2,ACAP2,FAM46A,FICD,LGMN,PHKA2,NR2C1,NAGA,TBC1D10B,ATG4D,MYO5B,DOCK4,CDKN2AIP,SEC23A,COG2,FOXJ2,CLSTN1,TEP1,UTRN,PRKCQ,PYGO1,CBL,ITPR3,ALCAM,TRIQK,ATP10D,ZNF469,CMTM7,NIN,EPHA10,JAK1,ACAD10,HAGHL,KIAA1804,TRIOBP,ZNF704,FAM195A,SLC27A1,NRG1,KLF5,MLKL,HS3ST3B1,NR3C2,COBL,MAMDC2,PRKAR1A,DENND5B,ANKRD13D,PCOLCE,ATP9A,CENPI,EPS8,PBX3,CYB561,PLD2,APOBEC3H,DNAH3,TMEM87B,PTEN,MGAT1,FUT8,FJX1,ATP8B1,ERBB3,MAP3K7,GFI1,TTPA,TRIM62,NCOA2,MSH6,PCCB,TGIF1,PDGFC,ARHGEF28,SHMT1,ARAP2,PAPD7,TCFL5,FURIN,DIAPH2,C2orf69,LRRC1,GRTP1,AIF1L,CDK5RAP1,RGS9,MAMDC4,FGFR2,RIN3,ABCB1,ERAP1,PGM2L1,GRIN2D,RABL6,FZD5,NCAPG2,ARSB,ESPL1,OCLN,DEF6,USP16,JARID2,RGMA,LTBP1,NMRK1,TMEM184B,CPT2,CAMKK1,EPHX4,VARS2,MPP5,DNER,CACNB4,KREMEN1,TMC1,PTCHD4,SH3KBP1,ARHGEF10L,NKAIN3,SIPA1L2,HSF2,LRRC6,ARHGEF37,TSPAN6,ANKFN1,PHTF1,DLG1,CAPG,POF1B,TRPC1,ARNT2,MYH14,TECR,SLC39A10,MYRIP,IL1RAP,CYP1B1,ATL1,TDP1,ASXL1,LAP3,RNF165,RGAG1,ADRBK2,TCN2,NEIL1,HPSE,MADD,IARS2,RBM43,APBA2,RAP1GAP,CAPN1,CPPED1,GRN,FAM213B,ARAP3,PPP1R12A,PEX6,PYROXD2,ASL,ABCG2,CALM3,PHLPP1,ADAMTSL4,TYW3,PFKL,FAM20C,KCNN4,COL6A1,EBF4,PRKCI,FXYD5,SRP54,FNIP1,LIMCH1,KNTC1,NPTN,ZRANB1,CCDC88A,SNED1,PODXL2,PARD3B,GYLTL1B,VWA1,PDE5A,BTN3A2,KIAA1109,HEATR5A,MFSD7,RANBP9,EGFR,RHPN1,MUM1L1,GNAS,FECH,TSC1,ONECUT1,INSR,CGREF1,RHOBTB2,YOD1,PITPNA,DONSON,SHROOM2,JAK3,FBXW5,CCNE2,LMO7,GAS2L1,NCKAP5,ZSWIM5,SORBS1,PDIA5,MORC4,COL18A1,PATL2,ARHGEF16,SLC25A48,SS18,ZNF687,ARTN,FRYL,SMO,DIXDC1,STEAP3,ECE1,ETHE1,NFKB2,LOXL1,UPF3A,EBAG9,PTPRU,SLC39A8,OSTM1,DUSP4,TMTC2,FANCE,DOCK5,PDHX,ARHGAP35,ALDH5A1,BFSP1,STAT6,TLE1,RCAN2,SPTBN5,PLXND1,CYP2U1,AKNA,REEP4,ABCA1,CBX4,GLIS3,ARHGEF11,ARHGEF7,LRP4,MIER3,COL4A5,NOTUM,SBF1,ITGA2B,TMEM63A,HDAC9,KIF5B,IL17RB,IRF2BPL,SNX13,CARD8,ADORA1,MLPH,LLGL2,BMP7,TOX2,KIAA0319,H2AFY,BRD7,IQGAP3,C12orf75,RPGR,MYO5A,SUN2,DCAF6,WNT10B,NR4A1,DEPDC4,GCLC,PHLDB3,ASPM,RC3H2,SYBU,OGDHL,LRRC66,TTC7A,POLD3,LEPR,SPAG1,MPV17L2,MAP1B,ARHGAP24,HLA-B,CASP7,RAP2C,UACA,GRAMD1C,PLOD3,SOX8,L1CAM,AHR,NGEF,ZNF596 |
| 1.980e-03 | -6.22 | negative regulation of protein transport | biological process | GO:0051224 | 197 | 45 | 16441 | 2455 |
TXN,LGR4,NFKBIE,THRA,RAB23,PSMD10,SYTL4,BARD1,FBLN1,ERP29,APC2,WWP2,NEO1,NOV,SP100,PFKL,BMP7,CABP1,UBE2J1,TMBIM6,DAB2IP,MDFIC,MAPK7,F2R,MDFI,CHP1,BAG4,ERLEC1,ACVR1C,DMTN,LITAF,PTGER4,RGCC,EZR,PIM3,SNX12,BANK1,WWTR1,NFKBIA,RAB11FIP1,PKD2,YOD1,NDFIP1,F2RL1,PKIA |
| 1.985e-03 | -6.22 | salivary gland development | biological process | GO:0007431 | 33 | 12 | 16441 | 2455 |
NKX3-1,TWSG1,FGFR2,BMP7,CST3,PLXND1,PLXNA1,SEMA3A,CLCN2,NFIB,DAG1,EGFR |
| 1.989e-03 | -6.22 | LIU_IL13_MEMORY_MODEL_DN | MSigDB lists | LIU_IL13_MEMORY_MODEL_DN | 5 | 4 | 17758 | 2588 |
IL13RA1,DUSP4,CBL,PFKFB2 |
| 1.998e-03 | -6.22 | PLCG1 events in ERBB2 signaling | REACTOME pathways | R-HSA-1251932 | 37 | 13 | 8202 | 1235 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,ERBB2,PRKAR2B,ITPR2,ITPR3,PRKACA,EGFR,PRKAR1A |
| 1.999e-03 | -6.22 | PRC1 (protein regulator of cytokinesis 1) | protein interactions | 9055 | 20 | 9 | 16036 | 2547 |
PLK1,CCNA2,TACC2,KIF23,RACGAP1,CENPE,CCNB1,CDK1,SH3KBP1 |
| 2.003e-03 | -6.21 | YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma) | protein interactions | 7532 | 370 | 80 | 16036 | 2547 |
LMO7,CASP3,TNK1,CAMKK1,KLC2,TP53,PKP2,MAGOHB,WEE1,SS18,ATP6V0B,INPP5E,RGS12,P4HB,FRYL,ZFP36,OSBPL3,N4BP3,CDKN1B,TIAM1,TUBA4A,MAP3K3,ING1,AKT1,PFKFB2,KIF1C,PRKCQ,MCFD2,CBL,CDC25C,VCP,OPTN,IRS2,MPRIP,WWTR1,CTNND1,CDK17,FAM189A2,PPP1R12A,CKAP2,TBC1D1,DCAF7,ARHGEF7,FRMD6,SHPRH,KIF23,RACGAP1,NCKAP1,FBXO6,LBR,RASSF8,KIF5B,IGF1R,RALGPS2,CDK16,CENPJ,PAK2,FAM13B,KLC3,CTPS1,TRIM21,ALDH7A1,MAPK7,SIMC1,MPHOSPH9,FARP2,PARD3B,PIK3R1,CAPNS1,CYFIP2,CRTC2,TSC1,RAB11FIP2,SH3BP4,FGD6,ARRB1,NDE1,CFAP20,TBC1D4,SHROOM2 |
| 2.006e-03 | -6.21 | HALLMARK_UV_RESPONSE_DN | MSigDB lists | HALLMARK_UV_RESPONSE_DN | 142 | 34 | 17758 | 2588 |
LTBP1,RASA2,ERBB2,NOTCH2,ADD3,TGFBR3,IGF1R,PTEN,CYR61,DLG1,CDKN1B,PIK3CD,CITED2,ATP2B1,ABCC1,GCNT1,DUSP1,FBLN5,PAPD7,NR3C1,FHL2,PRKAR2B,NFIB,MAP1B,PIAS3,DDAH1,FYN,RND3,NR1D2,SIPA1L1,INPP4B,SFMBT1,ZMIZ1,ARHGEF9 |
| 2.006e-03 | -6.21 | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | 142 | 34 | 17758 | 2588 |
KLF2,GCLM,ARMCX3,CDKN1C,IL15,DNAJB2,FTH1,MAP1LC3B,PHLDA1,TNFSF9,DUSP5,DNAJB9,HSPA13,DGKG,NCOA2,DUSP1,ADAM17,CD55,SAT1,NFE2L1,FNDC3A,ZFAND5,STEAP1,BSDC1,STX3,GABARAPL1,FYN,RND3,P4HA2,ZNF165,GLA,HSPB1,MAFF,FOXA1 |
| 2.007e-03 | -6.21 | Acyl-CoA-binding_prot_CS | interpro domains | IPR022408 | 5 | 4 | 18293 | 2672 |
ACBD5,ECI2,ACBD3,DBI |
| 2.007e-03 | -6.21 | SERTA_dom | interpro domains | IPR009263 | 5 | 4 | 18293 | 2672 |
SERTAD2,CDCA4,SERTAD4,SERTAD3 |
| 2.007e-03 | -6.21 | Disulphide_isomerase | interpro domains | IPR005788 | 5 | 4 | 18293 | 2672 |
PDIA3,PDIA6,P4HB,PDIA4 |
| 2.013e-03 | -6.21 | TNF (tumor necrosis factor) | protein interactions | 7124 | 102 | 28 | 16036 | 2547 |
CPD,LAMP2,ADAM17,CELSR2,TNIP1,RALBP1,TRAF2,CDYL,SHARPIN,HSPA12A,CAPNS1,PDIK1L,TNFSF9,DAG1,SFXN5,RHEB,OPTN,NEO1,FAS,FYN,CSF1,ZFP36,MMP17,BDH1,NFKBIA,HSPA13,MAP3K7,HSPB1 |
| 2.013e-03 | -6.21 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Langerhans_cell_histiocytosis | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Langerhans_cell_histiocytosis | 61 | 18 | 17775 | 2585 |
PCDH1,AKT1,RET,TP53,ERBB2,IDH1,FLT3,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,ALPP,PIK3CA,SMO,JAK3 |
| 2.013e-03 | -6.21 | Langerhans_cell_histiocytosis | COSMIC cancer mutations | Langerhans_cell_histiocytosis | 61 | 18 | 17775 | 2585 |
PCDH1,AKT1,RET,TP53,ERBB2,IDH1,FLT3,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,FGFR2,ALPP,PIK3CA,SMO,JAK3 |
| 2.024e-03 | -6.20 | AMPK signaling | WikiPathways | WP1403 | 68 | 21 | 4455 | 729 |
PRKAA2,ACACB,SLC2A4,AKT1,CAMKK1,PIK3R1,PRKAA1,TP53,STRADB,CCNB1,LEPR,CRTC2,TSC1,PRKAG2,INSR,CCNA2,PIK3CA,GYS1,CAB39,ADIPOR1,PIK3CD |
| 2.027e-03 | -6.20 | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN | 47 | 15 | 17758 | 2588 |
TNS3,RAB3B,SORT1,ENO2,PIK3AP1,TBC1D1,CORO1C,SPINT2,UBE2D2,RYK,PRDM5,TMTC2,GM2A,DENND5B,BCL10 |
| 2.037e-03 | -6.20 | ESC_V6.5_UP_EARLY.V1_DN | MSigDB lists | ESC_V6.5_UP_EARLY.V1_DN | 169 | 39 | 17758 | 2588 |
ANXA3,PCOLCE,KLK10,MRAS,FAM198B,FBXO6,LTBP3,GBX2,CAPN2,C16orf74,RASSF8,CTGF,CYR61,CALD1,ABCA2,GYS1,TNFRSF12A,CRY2,TINAGL1,NTN1,SCARA3,LOXL1,CPE,S100A6,SP5,TIMP2,S100A4,FHL2,CCDC34,YES1,ALCAM,CMTM7,SOCS3,AXL,NAB2,MAPK13,FZD5,F2RL1,COL16A1 |
| 2.040e-03 | -6.19 | LPAR6 (lysophosphatidic acid receptor 6) | protein interactions | 10161 | 52 | 17 | 16036 | 2547 |
SLC25A24,TMEM184B,NLRX1,TSPAN15,PKP2,KDELR3,ERBB2,STK17B,SFXN5,PDXDC1,STX10,JAK1,FASTKD1,BDH1,TNPO2,BRAT1,KNTC1 |
| 2.040e-03 | -6.19 | ISLR (immunoglobulin superfamily containing leucine-rich repeat) | protein interactions | 3671 | 52 | 17 | 16036 | 2547 |
CHSY3,NEK4,ARSK,PGAP1,SGPL1,CD109,SLC25A4,BMP7,ATP13A3,SLC25A40,GALNS,PCYOX1,XRCC3,CNPY3,MGAT5,TUBA4A,GCNT1 |
| 2.040e-03 | -6.19 | negative regulation of cell adhesion | biological process | GO:0007162 | 219 | 49 | 16441 | 2455 |
CASP3,NF2,SERPINE2,LGALS3,UBASH3B,CBLL1,ERBB2,CD274,FBLN1,RND1,BMP2,EPCAM,CDH1,PTEN,TBCD,BCL6,DLG1,PRKG1,ADAM15,FXYD5,TACSTD2,ERBB3,C10orf54,MAPK7,SOCS5,CYP1B1,EPB41L5,CASK,MFI2,FZD4,ITCH,DMTN,PIK3R1,PPARA,RGCC,PDE5A,ARHGDIB,FZD7,RASA1,AP1AR,SWAP70,SEMA4D,ACVRL1,CORO1C,SPINT2,NDFIP1,JAK3,PRKAR1A,IRF1 |
| 2.051e-03 | -6.19 | toll-like receptor 5 signaling pathway | biological process | GO:0034146 | 69 | 20 | 16441 | 2455 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 2.051e-03 | -6.19 | toll-like receptor 10 signaling pathway | biological process | GO:0034166 | 69 | 20 | 16441 | 2455 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 2.062e-03 | -6.18 | STTTCRNTTT_V$IRF_Q6 | MSigDB lists | STTTCRNTTT_V$IRF_Q6 | 180 | 41 | 17758 | 2588 |
DDX58,GSDMD,ELK4,SORBS1,KLHL13,PSME2,TAP1,PSME1,OSR2,BCL2L1,PSIP1,LGALS3BP,IL22RA1,CDKN2C,CCND1,DTX3L,PPP1R10,MGAT4A,BHLHE41,TRIM21,CITED2,DLX4,PSMA5,PCGF5,ASXL1,USP18,NUB1,SYNE2,IFIT3,NFIX,PITX2,TAPBP,CASP7,C19orf66,CCDC6,NOD2,MAP3K11,SFMBT1,NRG1,NR3C2,CBX4 |
| 2.063e-03 | -6.18 | V$IK2_01 | MSigDB lists | V$IK2_01 | 258 | 55 | 17758 | 2588 |
ELK4,LTBP1,BMF,ARAP3,ST13,NFKBIE,PPP1R12A,IGFBP6,RASA2,RNF182,VARS2,SORBS3,OSR2,ETS1,GNB2,HOXB2,CYP26A1,NRP2,SYTL2,IRF2BPL,PAK6,CTGF,IGF1R,RALGPS2,SHC3,TACC2,PRICKLE3,ELF5,FAM20B,TFAP2A,CDKN1B,NCOA2,RBMS2,DOCK4,HES1,PDGFC,TGIF1,HN1L,DENND1B,SAT1,VAMP3,KBTBD8,COL12A1,CXXC4,KLF12,AMMECR1,PRPS2,AGBL5,OVOL1,SP6,GRAMD1C,NRGN,PKIA,JARID2,HS6ST3 |
| 2.070e-03 | -6.18 | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | 191 | 43 | 17758 | 2588 |
ANXA3,LGALS3,SEC61G,AK7,EPHX4,MCCC1,TDRKH,PSME1,RAB6A,POMGNT1,C11orf95,DUSP5,NCS1,TMEM62,CEP78,EBF4,APIP,DLG3,F2R,MED30,SUSD3,LAMP2,MLEC,PLSCR1,LPGAT1,C1GALT1C1,CCBL2,RNF19B,FRMD4B,MTFMT,GNPTAB,PEX2,MATN2,RYK,PPP2R3C,ALG2,MLKL,GEM,TTC39C,CHPT1,MAD2L1BP,AHR,DRD1 |
| 2.072e-03 | -6.18 | cytoplasmic side of membrane | cellular component | GO:0098562 | 168 | 39 | 17570 | 2579 |
TNK1,FARP1,TRAF2,IQGAP1,RASA2,GNAL,RACGAP1,TEC,SNX9,CACNB4,SPTB,CDH1,CDK16,SNX18,PTEN,CABP1,DLG1,DAB2IP,TIAM1,SYK,GM2A,S100A6,EZR,YES1,GNA11,RASA1,TXK,GNAS,RGS9,FYN,LDLRAP1,JAK1,ARRB1,PKD2,CHMP4B,GEM,JAK3,TRAF5,ESYT2 |
| 2.078e-03 | -6.18 | NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha) | protein interactions | 4792 | 141 | 36 | 16036 | 2547 |
HOXB7,RPS6KA1,TP53,CUL1,CHAC2,SPDL1,BARD1,ZNF212,CAPN2,PRKCI,MAP3K7,NFKB2,MAP3K3,UFD1L,RHOA,DCAF6,PIK3R1,OGDHL,YES1,SLC25A5,PSMA4,VCP,RASA1,SOCS3,BCL10,SCRN2,SLC25A4,HOXA9,UBE2D2,STAT1,AURKA,ARRB1,HDAC1,HSPB1,CAPN1,RPS6KA3 |
| 2.085e-03 | -6.17 | positive regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043123 | 176 | 41 | 16441 | 2455 |
PINK1,TRIM5,TRAF2,IL18,SLC20A1,TNFRSF19,IL18R1,CTNNB1,IRAK1,TSPAN6,ZDHHC13,SLC44A2,TFG,MAP3K7,F2R,TRIM62,S100A13,EEF1D,CTH,MAP3K3,CXXC5,RHOA,TRIM8,RIPK2,S100A4,SHARPIN,LITAF,PRKCQ,CD40,BCL10,PTGS2,FYN,GPRC5B,PELI2,PLK2,SECTM1,NOD2,CANT1,NDFIP1,TRAF5,F2RL1 |
| 2.093e-03 | -6.17 | Collagen biosynthesis and modifying enzymes | REACTOME pathways | R-HSA-1650814 | 64 | 19 | 8202 | 1235 |
ADAMTS2,COL9A3,COL6A2,PCOLCE,P3H2,COL18A1,COL4A5,COL7A1,COL12A1,P4HB,COL13A1,PLOD2,COL6A1,BMP1,ADAMTS14,PLOD3,COL16A1,CRTAP,TLL2 |
| 2.115e-03 | -6.16 | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_II | 34 | 12 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,GNA11,EGFR |
| 2.115e-03 | -6.16 | serous | COSMIC cancer mutations | serous | 34 | 12 | 17775 | 2585 |
RB1,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 2.115e-03 | -6.16 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | 34 | 12 | 17775 | 2585 |
RB1,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,FLT3,JAK3,EGFR |
| 2.133e-03 | -6.15 | AACTGGA,MIR-145 | MSigDB lists | AACTGGA,MIR-145 | 219 | 48 | 17758 | 2588 |
TRIM2,CPEB4,NUAK1,RASA2,SOX9,UBE2Z,DNAJB11,MPP5,CCNL1,CAMK1D,HERC6,ZFYVE9,AKIRIN1,CTNNBIP1,ADD3,DPYSL2,RGS3,CABP1,VASN,MDFIC,TAGLN2,ACSL4,CITED2,SCN3A,MYO5A,MAP3K3,EPB41L5,AMOTL2,ZC3H11A,ACBD3,NFE2L1,YES1,FNDC3A,LHFPL2,DAG1,RASA1,ABR,FZD7,ABLIM2,ARHGAP24,CACHD1,SLC4A4,KLF5,EIF4EBP2,CTNND1,AKIP1,SEMA3A,ABCA1 |
| 2.135e-03 | -6.15 | CELL_FRACTION | MSigDB lists | CELL_FRACTION | 486 | 94 | 17758 | 2588 |
LAMP1,IL15,TP53,SLC7A2,MGST2,KREMEN1,KTN1,CYP39A1,SYTL2,STEAP2,FUT1,ECE1,CTTN,PDE4D,OAS3,PXMP4,CTDSP2,RASGRP1,LAMP2,CPD,PPIF,CD55,MCTP1,SNTB2,TEP1,UTRN,ARFRP1,SLC17A5,PKMYT1,ICMT,DAG1,VCP,ATP1A1,ALDH5A1,IDE,SLC9A6,WFS1,PPP2R4,ARF6,RAP1GAP,ABCA1,GCLM,GALK1,HSP90B1,TSPAN15,MAN1A2,MCTP2,STRN4,SLC1A3,POMGNT1,FBLN1,MERTK,EFNB1,NRP2,B4GALNT1,ADRBK1,SLC16A6,A4GALT,TPST1,ATP8B1,TMBIM6,CD70,TSPAN13,HSPA13,SLC12A2,SLC16A5,TMED2,CKAP4,MED22,TMX1,KDELR1,ABCC1,FADS2,FBLN5,MMD,MPP1,AMFR,RC3H2,CYFIP2,BCAR1,FAS,GALNT3,HLA-B,SCARB2,FAAH,HTT,SPINT2,SLC4A3,MPP2,DGAT2,ABCB1,CSGALNACT1,ARRB1,PTGES |
| 2.137e-03 | -6.15 | Tetraspannin | pfam domains | PF00335 | 33 | 12 | 16629 | 2504 |
TSPAN15,CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN13,TSPAN1,CD81,TSPAN17,TSPAN7,TSPAN33 |
| 2.137e-03 | -6.15 | UEDA_PERIFERAL_CLOCK | MSigDB lists | UEDA_PERIFERAL_CLOCK | 164 | 38 | 17758 | 2588 |
LMO7,NDRG1,PNPLA2,GNE,HAL,ASL,COL18A1,DNAJB11,DHRS3,KIAA1161,PER2,PDIA4,MESDC2,CD9,BRI3,KLF9,ERBB3,ETHE1,F2R,CKS2,GCLC,CRIP2,SPATA13,PPARA,LITAF,FBXO8,HTATIP2,SLC11A2,GLO1,PNKD,ALCAM,POR,GABARAPL1,ONECUT1,BTG1,NR1D2,TLE1,ST3GAL1 |
| 2.137e-03 | -6.15 | PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | PROTEIN_COMPLEX_ASSEMBLY | 164 | 38 | 17758 | 2588 |
WASF3,AGRN,REPS2,AASS,TRAF2,TP53,TGFBR1,APBA1,APC2,SLC9A3R2,ZFYVE9,PICK1,IGF1R,IRAK1,BAX,CD9,TLN2,SYK,IL1RAP,TCEB2,AMFR,VAMP3,CDA,COX11,CD40,ANLN,NUBP1,DAG1,RANBP9,FAS,BCL10,TAPBP,INSR,ALDH5A1,NOD2,MAP3K11,HMGA1,OCLN |
| 2.137e-03 | -6.15 | diffuse_adenocarcinoma | COSMIC cancer mutations | diffuse_adenocarcinoma | 4562 | 723 | 17775 | 2585 |
ACACB,KLK10,FAM160B1,AK7,TRIM5,SLC25A13,DNAJC3,CACNA2D2,CCNO,DHX8,NRG2,TRAPPC8,LGI3,BAIAP3,ISOC2,DPP8,SNX9,KIF26A,CARD10,LTBP3,GRM5,EPDR1,CDKN2C,DAPK2,NAPG,ZYX,AP1M2,RGS12,TGFBR3,MUC4,DNAH6,PPP1R16A,SLC46A1,ATP13A3,MANF,TIAM1,ODF2L,TUBA4A,NWD1,FBXL16,SH3BGRL,DSTN,TMEM151A,TFAP2C,PRKAR2B,LOXL2,COL12A1,LCP1,PGF,PLCG1,WDR11,GRID2IP,DNM1L,ATP7B,FAM114A1,MAP3K11,E2F8,SCN5A,NFKBIE,SOX9,STRN4,ZNRF3,GPSM2,TTYH3,ELF3,GNS,DNPEP,FRY,FAM189A1,MEGF8,ZIC5,FBXO7,CADPS2,ALPK1,STT3B,PANX2,NCAM1,DGKG,C9orf72,PAQR7,KIF20A,STAT4,FHL2,NPHP3,MEST,SPTLC2,GNA11,DHX32,IL1R1,CACHD1,NCOA3,NAAA,ETS2,HTT,TIMM8A,ITPR1,CLMN,OSMR,DYSF,DRP2,TRPC3,RPS6KA3,XDH,ADAMTS16,DMPK,DOCK9,LFNG,ACTR8,APOO,WDTC1,RGS20,IL13RA1,FAM91A1,ZNF385B,CDS1,UHRF1BP1L,CCND1,RBM23,MUC16,ST5,SCNN1A,CDH1,SP100,DACT1,XYLT2,RASGEF1A,SNX10,MYT1,SCN3A,TMCC2,ENPP4,CAMSAP3,COL6A2,PFKFB2,SEPT6,SYNE2,NUSAP1,TRIM7,GIGYF1,STX10,PDLIM3,CCNB3,SHROOM3,AXL,SIPA1L1,WWTR1,PLEKHG1,PNPLA6,TTC8,FARP1,TNRC6C,TAOK2,CKAP2,SDC4,FLOT1,PDIA3,CTSZ,PKN1,PLPPR4,HOXB2,NEO1,ANK1,ANKS1B,FAM160A2,KNDC1,GPC3,TUBGCP6,TMBIM6,WWP1,NPTXR,RAG1,CRTAP,PARP9,HCN3,ADAMTS2,CTNNAL1,RAPGEF2,PIK3R1,MRS2,MYEOV,PGBD1,SNTB1,SKA1,CRISPLD2,CNTNAP1,DCAF10,LDLRAP1,PLOD2,RAB11FIP2,ZFP30,SLC35B3,FAM3C,ARFGAP3,FBXO44,ITGAV,FHL1,NUP37,USF2,DCBLD1,ACOT7,TLL2,TMEM131,SIGIRR,TRIM2,AGRN,EPAS1,FHDC1,ARFGEF1,TEX2,F11R,NENF,HDAC6,NUP62CL,SPTB,PLS3,BTG3,CPNE2,ENTPD4,PCNA,NUP210,TM9SF2,CTNNB1,SHC3,MKRN3,PAPSS1,ABCA2,DUSP10,RGS5,TLN2,MYBL1,TRAM1,NEB,MARK1,CELSR2,STAU2,NFE2L1,EZR,KLK6,NKAIN1,FAM212B,ANLN,CLCN2,VCP,TNS4,HS6ST1,TBC1D17,MAP2,DOLPP1,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,HS6ST3,USH1C,RASA2,SORBS3,CNTNAP2,DOCK11,RSAD1,PGAP1,ANO1,MYO5C,B4GALNT1,UBE2Q2,IGF1R,SPIN4,FRAS1,FCHO1,PIM1,PLCB2,ABCC1,CHSY3,DPYSL5,MRPS33,TESK1,ZNF320,MGAT4B,ZSCAN12,UNC45B,ANKRD29,ZDHHC3,FA2H,COL13A1,PHLPP2,CSF1,MFSD2A,P4HA3,NLRC5,LTBP2,PLD1,ZDBF2,SEMA3A,CDAN1,FAM45A,KCNAB3,NF2,UGP2,CTDSPL,TMX4,XYLT1,TP53,ERBB2,P2RX7,CCNL1,LPIN3,KBTBD11,SYTL2,CDK14,TTC21B,SRPX,WDR44,TACC2,EFR3A,PPME1,PLK4,ZDHHC23,ESPN,NOTCH3,OAS3,MINPP1,SCN2A,LMAN1,CTH,CPD,AKT1,COQ10B,MYPOP,ZNF628,PTPRJ,ABHD12,RBL1,PTK7,ADAMTS14,MAOA,ANXA9,ARHGAP4,NDST3,ZC3HC1,COL9A3,DYRK3,CDH22,CPEB4,TAB3,GNAL,MCTP2,NKRF,JAG2,IL22RA1,PPP2R3A,NRP2,CD109,FOXP2,ALPP,MAGEE1,IL17RA,BUB1,ABCD1,HMGCL,ATP2B1,FAH,IGDCC4,NFE2L3,DLGAP1,RHOA,HMGN5,GUSB,NR3C1,PRICKLE1,TRIM35,GGH,COL7A1,AKAP3,FXR2,FNDC3A,RNPEP,TXNDC11,USP6,CNOT2,FUCA1,BANK1,FAT4,NIPSNAP3A,E2F1,FAM117A,ICOSLG,TBC1D4,ARHGEF9,PKIA,ARHGEF4,LAMP1,GAA,SLC35D2,PPP4R4,HSPG2,SSH1,ATP8A1,PPFIBP2,CUL1,FAM101B,ELMOD2,ELMO2,RGS3,PRICKLE3,IQCE,PIK3CA,KCNS3,ATRNL1,MTMR11,MARCH2,LOC81691,SGCE,SPATA18,SNTB2,KIF13A,TNS1,GALNT7,LDB2,CCNF,TP53I3,PRIM1,AHRR,RBM47,GDE1,GNPTAB,SH2D3C,TBX1,PPP2R4,NKD1,BMP1,PRDM5,NFKBIZ,WBSCR27,UNC5B,DLAT,FGD1,RECQL,INPPL1,CDK17,CALB2,NOTCH2,SLC1A3,PDXDC1,TSPAN7,PSIP1,MECOM,DOPEY2,ITGA3,VASN,AIM1,MSH2,RUNDC3B,TPST1,CTPS1,PRKG1,SORL1,CD70,CACNA1D,SYTL3,GPR161,RIMS2,TRAK2,IGSF3,DNAI1,EPB41L5,GFPT1,PMPCB,B3GNT7,MFI2,ZNF84,MMD,CEP89,ADCK3,AMER1,PTPRH,DCHS1,WHSC1,PYGL,ATP8B3,PKM,KDM3A,ANTXR1,RASA1,PDE11A,NT5C2,PLEKHH2,FGD6,PCDH19,CABIN1,PER3,MAP3K5,PKD1L2,FRMPD3,PLA2G4A,TCF25,CAPN12,ARMCX3,CEP70,TRIP10,TMEM217,ST14,SUZ12,ATP2C2,TMEM19,ART5,SLC25A35,APLP2,ACAP2,TRANK1,RALB,CDKN1B,MYO5B,DOCK4,SLC5A11,SEC23A,COG2,UTRN,KIF1C,CBL,ITPR3,ALCAM,SP4,ZNF469,NIN,EPHA10,FYN,JAK1,DDOST,KIAA1804,STAT1,NRG1,ZC3H12B,NR3C2,COBL,ATMIN,MAMDC2,PLSCR4,SLC16A14,ATP9A,EPS8,CCNJL,HERC5,PBX3,DNAH3,PTEN,CENPJ,FJX1,SLC44A2,ERBB3,TRIM62,SLC16A5,MSH6,SMC4,FARP2,PCCB,RASGRF1,PDGFC,ZWINT,ARAP2,CASK,LONRF3,ZC3H11A,MPP1,ZKSCAN2,DIAPH2,C2orf69,ACADSB,FGFR2,TBX18,RIN3,SLC25A40,ABCB1,RABL6,WDR91,WDR62,ARSB,ESPL1,CXorf56,OCLN,DEF6,RGMA,ESYT2,EXPH5,LTBP1,FAF2,EPHX4,MAP1LC3B,DNER,CACNB4,DENND2D,TRIM68,ZFYVE16,SIPA1L2,LRRC6,CDKL5,ANKFN1,DLG1,RP2,PTPRE,MYRIP,IL1RAP,ASXL1,FOPNL,ITCH,ARHGDIB,MRPS18A,PTGFRN,EDNRA,FASTKD1,MADD,TDRD7,IARS2,TRIM45,MIIP,NR2C2,GRN,PPP1R2,ZNF395,PPP1R12A,BVES,ASL,PM20D2,SAMD9,ADAMTSL4,DUSP5,FAM20C,PFKL,OCRL,COL6A1,PRKCI,FXYD5,LIMCH1,ACAD8,ZRANB1,SLC12A2,GAD1,LRIF1,ALS2CL,SNED1,GYLTL1B,PDE5A,HMG20B,VWA1,HEATR5A,NUBP1,AMDHD1,EGFR,SOX13,TSC1,INSR,UAP1,TMEM30A,SPAG7,RHOBTB2,ALPK3,CTSA,SHROOM2,JAK3,COL16A1,PROM2,NCKAP5,SLC25A24,PDIA5,COL18A1,IL27RA,TDRKH,ARHGEF16,KCTD15,ZNF687,KIF14,SMO,RPN2,EPB41L4B,F2R,TAF5,PTPRU,SLC39A8,IGSF8,DOCK5,SOCS3,ARHGAP35,HSF4,BHLHB9,STAT6,VSIG10,PLXND1,AKNA,SGOL1,ABCA1,LNP1,LIFR,GLIS3,ARHGEF11,ARHGEF7,SHPRH,JKAMP,FRMD6,MIER3,TGFBR1,AES,COL4A5,INTS8,TRMT2B,TRIB2,SYDE2,SNX13,TAF1B,LLGL2,BMP7,TOX2,TRIM3,ARVCF,HSPA13,IQGAP3,DCAF6,DEPDC4,LEPR,MAP1B,ENDOD1,C2orf70,RND3,UBE2D2,ATP6V1C1,AHR |
| 2.137e-03 | -6.15 | stomach-carcinoma-diffuse_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-diffuse_adenocarcinoma | 4562 | 723 | 17775 | 2585 |
ACACB,KLK10,FAM160B1,AK7,TRIM5,SLC25A13,DNAJC3,CACNA2D2,CCNO,DHX8,NRG2,TRAPPC8,LGI3,BAIAP3,ISOC2,DPP8,SNX9,KIF26A,CARD10,LTBP3,GRM5,EPDR1,CDKN2C,DAPK2,NAPG,ZYX,AP1M2,RGS12,TGFBR3,MUC4,DNAH6,PPP1R16A,SLC46A1,ATP13A3,MANF,TIAM1,ODF2L,TUBA4A,NWD1,FBXL16,SH3BGRL,DSTN,TMEM151A,TFAP2C,PRKAR2B,LOXL2,COL12A1,LCP1,PGF,PLCG1,WDR11,GRID2IP,DNM1L,ATP7B,FAM114A1,MAP3K11,E2F8,SCN5A,NFKBIE,SOX9,STRN4,ZNRF3,GPSM2,TTYH3,ELF3,GNS,DNPEP,FRY,FAM189A1,MEGF8,ZIC5,FBXO7,CADPS2,ALPK1,STT3B,PANX2,NCAM1,DGKG,C9orf72,PAQR7,KIF20A,STAT4,FHL2,NPHP3,MEST,SPTLC2,GNA11,DHX32,IL1R1,CACHD1,NCOA3,NAAA,ETS2,HTT,TIMM8A,ITPR1,CLMN,OSMR,DYSF,DRP2,TRPC3,RPS6KA3,XDH,ADAMTS16,DMPK,DOCK9,LFNG,ACTR8,APOO,WDTC1,RGS20,IL13RA1,FAM91A1,ZNF385B,CDS1,UHRF1BP1L,CCND1,RBM23,MUC16,ST5,SCNN1A,CDH1,SP100,DACT1,XYLT2,RASGEF1A,SNX10,MYT1,SCN3A,TMCC2,ENPP4,CAMSAP3,COL6A2,PFKFB2,SEPT6,SYNE2,NUSAP1,TRIM7,GIGYF1,STX10,PDLIM3,CCNB3,SHROOM3,AXL,SIPA1L1,WWTR1,PLEKHG1,PNPLA6,TTC8,FARP1,TNRC6C,TAOK2,CKAP2,SDC4,FLOT1,PDIA3,CTSZ,PKN1,PLPPR4,HOXB2,NEO1,ANK1,ANKS1B,FAM160A2,KNDC1,GPC3,TUBGCP6,TMBIM6,WWP1,NPTXR,RAG1,CRTAP,PARP9,HCN3,ADAMTS2,CTNNAL1,RAPGEF2,PIK3R1,MRS2,MYEOV,PGBD1,SNTB1,SKA1,CRISPLD2,CNTNAP1,DCAF10,LDLRAP1,PLOD2,RAB11FIP2,ZFP30,SLC35B3,FAM3C,ARFGAP3,FBXO44,ITGAV,FHL1,NUP37,USF2,DCBLD1,ACOT7,TLL2,TMEM131,SIGIRR,TRIM2,AGRN,EPAS1,FHDC1,ARFGEF1,TEX2,F11R,NENF,HDAC6,NUP62CL,SPTB,PLS3,BTG3,CPNE2,ENTPD4,PCNA,NUP210,TM9SF2,CTNNB1,SHC3,MKRN3,PAPSS1,ABCA2,DUSP10,RGS5,TLN2,MYBL1,TRAM1,NEB,MARK1,CELSR2,STAU2,NFE2L1,EZR,KLK6,NKAIN1,FAM212B,ANLN,CLCN2,VCP,TNS4,HS6ST1,TBC1D17,MAP2,DOLPP1,CTNND1,PIK3C2B,PIEZO1,EPB41L4A,HS6ST3,USH1C,RASA2,SORBS3,CNTNAP2,DOCK11,RSAD1,PGAP1,ANO1,MYO5C,B4GALNT1,UBE2Q2,IGF1R,SPIN4,FRAS1,FCHO1,PIM1,PLCB2,ABCC1,CHSY3,DPYSL5,MRPS33,TESK1,ZNF320,MGAT4B,ZSCAN12,UNC45B,ANKRD29,ZDHHC3,FA2H,COL13A1,PHLPP2,CSF1,MFSD2A,P4HA3,NLRC5,LTBP2,PLD1,ZDBF2,SEMA3A,CDAN1,FAM45A,KCNAB3,NF2,UGP2,CTDSPL,TMX4,XYLT1,TP53,ERBB2,P2RX7,CCNL1,LPIN3,KBTBD11,SYTL2,CDK14,TTC21B,SRPX,WDR44,TACC2,EFR3A,PPME1,PLK4,ZDHHC23,ESPN,NOTCH3,OAS3,MINPP1,SCN2A,LMAN1,CTH,CPD,AKT1,COQ10B,MYPOP,ZNF628,PTPRJ,ABHD12,RBL1,PTK7,ADAMTS14,MAOA,ANXA9,ARHGAP4,NDST3,ZC3HC1,COL9A3,DYRK3,CDH22,CPEB4,TAB3,GNAL,MCTP2,NKRF,JAG2,IL22RA1,PPP2R3A,NRP2,CD109,FOXP2,ALPP,MAGEE1,IL17RA,BUB1,ABCD1,HMGCL,ATP2B1,FAH,IGDCC4,NFE2L3,DLGAP1,RHOA,HMGN5,GUSB,NR3C1,PRICKLE1,TRIM35,GGH,COL7A1,AKAP3,FXR2,FNDC3A,RNPEP,TXNDC11,USP6,CNOT2,FUCA1,BANK1,FAT4,NIPSNAP3A,E2F1,FAM117A,ICOSLG,TBC1D4,ARHGEF9,PKIA,ARHGEF4,LAMP1,GAA,SLC35D2,PPP4R4,HSPG2,SSH1,ATP8A1,PPFIBP2,CUL1,FAM101B,ELMOD2,ELMO2,RGS3,PRICKLE3,IQCE,PIK3CA,KCNS3,ATRNL1,MTMR11,MARCH2,LOC81691,SGCE,SPATA18,SNTB2,KIF13A,TNS1,GALNT7,LDB2,CCNF,TP53I3,PRIM1,AHRR,RBM47,GDE1,GNPTAB,SH2D3C,TBX1,PPP2R4,NKD1,BMP1,PRDM5,NFKBIZ,WBSCR27,UNC5B,DLAT,FGD1,RECQL,INPPL1,CDK17,CALB2,NOTCH2,SLC1A3,PDXDC1,TSPAN7,PSIP1,MECOM,DOPEY2,ITGA3,VASN,AIM1,MSH2,RUNDC3B,TPST1,CTPS1,PRKG1,SORL1,CD70,CACNA1D,SYTL3,GPR161,RIMS2,TRAK2,IGSF3,DNAI1,EPB41L5,GFPT1,PMPCB,B3GNT7,MFI2,ZNF84,MMD,CEP89,ADCK3,AMER1,PTPRH,DCHS1,WHSC1,PYGL,ATP8B3,PKM,KDM3A,ANTXR1,RASA1,PDE11A,NT5C2,PLEKHH2,FGD6,PCDH19,CABIN1,PER3,MAP3K5,PKD1L2,FRMPD3,PLA2G4A,TCF25,CAPN12,ARMCX3,CEP70,TRIP10,TMEM217,ST14,SUZ12,ATP2C2,TMEM19,ART5,SLC25A35,APLP2,ACAP2,TRANK1,RALB,CDKN1B,MYO5B,DOCK4,SLC5A11,SEC23A,COG2,UTRN,KIF1C,CBL,ITPR3,ALCAM,SP4,ZNF469,NIN,EPHA10,FYN,JAK1,DDOST,KIAA1804,STAT1,NRG1,ZC3H12B,NR3C2,COBL,ATMIN,MAMDC2,PLSCR4,SLC16A14,ATP9A,EPS8,CCNJL,HERC5,PBX3,DNAH3,PTEN,CENPJ,FJX1,SLC44A2,ERBB3,TRIM62,SLC16A5,MSH6,SMC4,FARP2,PCCB,RASGRF1,PDGFC,ZWINT,ARAP2,CASK,LONRF3,ZC3H11A,MPP1,ZKSCAN2,DIAPH2,C2orf69,ACADSB,FGFR2,TBX18,RIN3,SLC25A40,ABCB1,RABL6,WDR91,WDR62,ARSB,ESPL1,CXorf56,OCLN,DEF6,RGMA,ESYT2,EXPH5,LTBP1,FAF2,EPHX4,MAP1LC3B,DNER,CACNB4,DENND2D,TRIM68,ZFYVE16,SIPA1L2,LRRC6,CDKL5,ANKFN1,DLG1,RP2,PTPRE,MYRIP,IL1RAP,ASXL1,FOPNL,ITCH,ARHGDIB,MRPS18A,PTGFRN,EDNRA,FASTKD1,MADD,TDRD7,IARS2,TRIM45,MIIP,NR2C2,GRN,PPP1R2,ZNF395,PPP1R12A,BVES,ASL,PM20D2,SAMD9,ADAMTSL4,DUSP5,FAM20C,PFKL,OCRL,COL6A1,PRKCI,FXYD5,LIMCH1,ACAD8,ZRANB1,SLC12A2,GAD1,LRIF1,ALS2CL,SNED1,GYLTL1B,PDE5A,HMG20B,VWA1,HEATR5A,NUBP1,AMDHD1,EGFR,SOX13,TSC1,INSR,UAP1,TMEM30A,SPAG7,RHOBTB2,ALPK3,CTSA,SHROOM2,JAK3,COL16A1,PROM2,NCKAP5,SLC25A24,PDIA5,COL18A1,IL27RA,TDRKH,ARHGEF16,KCTD15,ZNF687,KIF14,SMO,RPN2,EPB41L4B,F2R,TAF5,PTPRU,SLC39A8,IGSF8,DOCK5,SOCS3,ARHGAP35,HSF4,BHLHB9,STAT6,VSIG10,PLXND1,AKNA,SGOL1,ABCA1,LNP1,LIFR,GLIS3,ARHGEF11,ARHGEF7,SHPRH,JKAMP,FRMD6,MIER3,TGFBR1,AES,COL4A5,INTS8,TRMT2B,TRIB2,SYDE2,SNX13,TAF1B,LLGL2,BMP7,TOX2,TRIM3,ARVCF,HSPA13,IQGAP3,DCAF6,DEPDC4,LEPR,MAP1B,ENDOD1,C2orf70,RND3,UBE2D2,ATP6V1C1,AHR |
| 2.138e-03 | -6.15 | bone maturation | biological process | GO:0070977 | 14 | 7 | 16441 | 2455 |
BMP2,PHOSPHO1,RHOA,FAT4,SEMA4D,ANO6,DCHS1 |
| 2.138e-03 | -6.15 | cell adhesion mediated by integrin | biological process | GO:0033627 | 14 | 7 | 16441 | 2455 |
NOV,ADAM17,NPNT,ITGA6,COL16A1,L1CAM,ICAM1 |
| 2.141e-03 | -6.15 | regulation of cellular protein localization | biological process | GO:1903827 | 504 | 99 | 16441 | 2455 |
LZTFL1,SORBS1,TXN,NF2,THRA,TP53,ERBB2,IL18,BCL2L1,CCNB1,MICALL2,PRKACA,BARD1,APC2,BCAP31,ARHGEF16,NOV,CDH1,SP100,CTNNB1,RALB,DACT1,CABP1,DLG1,SMO,TAX1BP3,DAB2IP,TMBIM1,CHP1,SIRT1,VPS11,ERLEC1,TRIM8,BAG4,AKT1,DMTN,BNIP3L,NBPF3,EZR,PRKCQ,CDK1,LCP1,FZD7,PTGS2,FYN,PPP2R5A,WWTR1,RAB29,NRG1,ARF6,DDX58,TCAF1,PINK1,BMF,NFKBIE,RAB23,PSMD10,TGFBR1,RACGAP1,IL18R1,LMNA,KIF5B,RB1,RAC2,ITGA3,BMP7,FAM20B,NEK2,UBE2J1,PRKCI,SORL1,MDFIC,WNT3A,MAPK7,MDFI,GCC2,HES1,RHOA,PIK3R1,LITAF,PLS1,KIF20B,TP53INP2,EGFR,CDK5R1,STX3,NUCB1,LDLRAP1,TMEM30A,NFKBIA,CDCA5,E2F1,OSCP1,PKD2,YOD1,GPER1,FZD5,TMEM173,PKIA |
| 2.141e-03 | -6.15 | REACTOME_SIGNALING_BY_RHO_GTPASES | MSigDB lists | REACTOME_SIGNALING_BY_RHO_GTPASES | 111 | 28 | 17758 | 2588 |
ARHGAP11A,RASGRF1,ARAP2,ARHGEF3,ARAP3,RHOA,ARHGEF11,RALBP1,RACGAP1,ARHGDIB,ARHGEF16,RHOB,ABR,SYDE2,ARHGAP35,ARHGAP24,RAC2,OCRL,FAM13B,ARAP1,RHOBTB2,ARHGAP4,STARD13,TIAM1,ARHGEF9,NGEF,ARHGEF4,FGD1 |
| 2.149e-03 | -6.14 | thyroid hormone binding | molecular function | GO:0070324 | 5 | 4 | 16491 | 2452 |
THRB,CRYM,THRA,ALDH1A3 |
| 2.155e-03 | -6.14 | PLASARI_TGFB1_TARGETS_1HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_1HR_UP | 34 | 12 | 17758 | 2588 |
HES1,PTGS2,CYR61,NR4A1,FGF18,SPATA13,EGR3,ZMIZ1,SPSB1,SLC20A1,CDK5R1,IER3 |
| 2.157e-03 | -6.14 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | 66 | 19 | 17758 | 2588 |
EXPH5,C3orf52,CXorf57,KCTD12,DUSP4,TRIB2,PHLDA1,EDNRA,ADORA1,PLK2,ITPR1,REEP1,MAP3K9,PDE4D,SPRY4,MOXD1,NEB,COBL,PKIA |
| 2.157e-03 | -6.14 | AMIT_EGF_RESPONSE_120_HELA | MSigDB lists | AMIT_EGF_RESPONSE_120_HELA | 66 | 19 | 17758 | 2588 |
AMOTL2,PLAUR,SAT1,RUNX3,GDF15,IL27RA,DUSP4,PHLDA1,DAG1,BCL10,IRS2,AREG,MCF2L,NAB2,ARRB1,EPHB4,GEM,MAFF,CYP1B1 |
| 2.157e-03 | -6.14 | RAS_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | RAS_PROTEIN_SIGNAL_TRANSDUCTION | 66 | 19 | 17758 | 2588 |
ARAP3,RHOA,RALBP1,ARHGDIB,MRAS,NOTCH2,RHOB,TSC1,LIMK1,ARAP1,FGD6,TAX1BP3,PLD1,ARF6,ARHGAP4,ABCA1,RASGRP1,FARP2,FGD1 |
| 2.161e-03 | -6.14 | protein serine/threonine/tyrosine kinase activity | molecular function | GO:0004712 | 42 | 14 | 16491 | 2452 |
PRKAA2,DYRK3,RPS6KA2,AKT1,MAPKAPK3,TESK1,RPS6KA1,MAP3K9,TESK2,SGK1,AURKA,AURKB,MAP3K7,PRKACA |
| 2.161e-03 | -6.14 | V$CART1_01 | MSigDB lists | V$CART1_01 | 208 | 46 | 17758 | 2588 |
HOXB7,KLHL13,CALB2,RAB6A,ZNF219,SPTB,TEAD3,GBX2,ZDHHC21,ARHGEF10L,CDKN2C,FOXP2,KCTD15,ANKS1B,CDKL5,CALD1,LMO4,ELF5,BCL6,CLDN4,ATP8B1,TACSTD2,MOXD1,MYT1,RIMS2,SEPHS1,HP1BP3,ACBD5,SMARCA2,PDGFC,PLEKHA6,SERTAD4,DENND1B,C1GALT1C1,ROR1,ITPR3,CBL,RAB2B,NFIX,FYN,ACADSB,PELI2,ARRB1,MAL2,REEP4,HIPK3 |
| 2.165e-03 | -6.14 | NDC80 (NDC80 kinetochore complex component) | protein interactions | 10403 | 61 | 19 | 16036 | 2547 |
AMOTL2,PLK1,ZWINT,SPC25,TNIP1,NDC80,CCDC68,PLS1,NUF2,AURKB,CCNB1,SKA1,RB1,PSMC2,KLC3,NEK2,AURKA,BUB1,NDE1 |
| 2.166e-03 | -6.13 | XU_GH1_AUTOCRINE_TARGETS_DN | MSigDB lists | XU_GH1_AUTOCRINE_TARGETS_DN | 132 | 32 | 17758 | 2588 |
FAM129B,CIT,GPR180,PLA2G16,RAVER2,CA2,MCF2L,GPC3,PIK3CA,FAM102A,ESPN,SLC39A10,GPX4,SULF2,KRT80,PCCB,COL12A1,MAGED2,TMEM164,TIMP3,MPRIP,HPSE,JAK1,NAT1,PLK2,RAB31,NETO2,EFNA5,POMT1,HOOK1,ISOC1,FAM134B |
| 2.169e-03 | -6.13 | GSE2706_2H_VS_8H_R848_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_DN | 175 | 40 | 17758 | 2588 |
PLA2G4A,DDX58,TXN,MACC1,PARP14,TRIM5,HAPLN3,ETV5,XIAP,HERC5,CUL1,HMGN3,PGAP1,DTX3L,TNS3,ITGB8,PIK3CA,ACSL4,SCYL3,APOBEC3G,IGSF3,PARP9,DOCK4,LAP3,ITCH,DUSP4,ARHGAP24,BTG1,PRKAG2,CASP7,PLOD2,NMI,STAT1,TDRD7,ARFGAP3,CMPK2,TBC1D4,SHROOM2,IFI6,DRD1 |
| 2.171e-03 | -6.13 | Rab GTPase binding | molecular function | GO:0017137 | 89 | 24 | 16491 | 2452 |
MYO5B,EXPH5,PIFO,RUSC2,NDRG1,SYTL4,MICALL2,CCDC64B,RIC1,SYTL2,OPTN,RABGGTA,ACAP2,MLPH,LLGL2,RAB11FIP2,RIN3,RAB11FIP1,MYRIP,C9orf72,SYTL3,RIMS2,MYO5A,EHD1 |
| 2.174e-03 | -6.13 | V$IRF1_01 | MSigDB lists | V$IRF1_01 | 236 | 51 | 17758 | 2588 |
ELK4,DDX58,GSDMD,SORBS1,IL15RA,SCOC,HOXB7,EPAS1,JKAMP,TAP1,GATA3,CCDC68,AKIRIN1,DTX3L,RNF220,LMO4,MITF,DLG1,FXYD5,DUSP10,TRIM21,TWIST1,MXD3,HLA-C,DLX4,RIMS2,PDGFC,PCGF5,TRIM8,USP18,SH3BGRL,SAT1,SYNE2,VAMP3,RGAG1,FBXO8,LDB2,KDM3A,PLEKHB1,NFIX,PITX2,TAPBP,NGFRAP1,TBX1,MAP3K11,LTBP2,LEMD1,NR3C2,FOXA1,EHD1,DOCK9 |
| 2.175e-03 | -6.13 | putrescine degradation III | BIOCYC pathways | HUMAN_PWY-0 | 9 | 6 | 907 | 172 |
MAOA,ALDH3B1,ALDH2,SAT2,ALDH3A2,SAT1 |
| 2.178e-03 | -6.13 | Smooth Muscle Contraction | REACTOME pathways | R-HSA-445355 | 29 | 11 | 8202 | 1235 |
MYL9,CALM2,SORBS1,CALD1,CALM1,MYLK,CALM3,ACTA2,SORBS3,MYL12A,MYL12B |
| 2.179e-03 | -6.13 | protease binding | molecular function | GO:0002020 | 104 | 27 | 16491 | 2452 |
CASP3,TIMP2,PINK1,MBP,CAST,AMFR,SERPINB9,TP53,FLOT1,FURIN,SELL,ADAMTSL4,TYSND1,VCP,RAD23A,BCL10,IL1R1,TIMP3,ITGA3,SERPINA1,TIMP1,STIM1,CST3,SERPINB6,CD70,ITGAV,FLOT2 |
| 2.180e-03 | -6.13 | cellular protein catabolic process | biological process | GO:0044257 | 516 | 101 | 16441 | 2455 |
FAF2,DNAJC3,PSME2,CUL4B,PTTG1,FBXO2,CUL1,UBE2Z,PSME1,MVB12B,CCNB1,HDAC6,RAD23A,PSMD1,KIF14,PSMC2,DAB2IP,TINAGL1,LGMN,PLK1,SIRT1,SEC61B,ERLEC1,FBXL16,SPATA18,ITCH,USP18,RNF11,CDC20,BNIP3L,VPS4B,RNF165,AURKB,CCNF,CBL,RNF19B,CDK1,VCP,ZMPSTE24,TRIM9,DNAJC10,IDE,PSMD3,WFS1,WWTR1,CHMP4B,AREL1,PSMC1,PINK1,HSP90B1,CIT,CTSB,JKAMP,DNAJB2,PSMD7,PSMD10,CTSZ,ZNRF3,FBXO6,DNAJB9,WWP2,CAPN2,RNF128,CTSC,FBXO7,NEK2,FBXL14,UBE2J1,PCYOX1,WWP1,USP38,USP1,STT3B,ZRANB1,MYLIP,PSMA5,UFD1L,USP31,PSMB4,AMFR,NUB1,UBE2A,FBXO9,FBXO8,TP53INP2,PSMA4,FBXO10,USP6,CTSL,CTSV,UBE2D2,AURKA,ARRB1,CTSA,YOD1,NDFIP1,UBE2C,RNF146,USP16,FBXW5,USP43 |
| 2.182e-03 | -6.13 | GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_UP | MSigDB lists | GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_UP | 186 | 42 | 17758 | 2588 |
PRSS8,MTM1,PPP1R12A,HSPG2,NUAK1,CBLL1,CUL1,ASAH1,DPP8,NUP62CL,SRPX2,CCDC92,CD46,SNTA1,CARD8,FAM189A1,FRYL,GPC3,COL6A1,PSMA5,CERS2,FRS3,SYPL1,GCA,CASK,ACBD3,PPARA,DBR1,LITAF,RNF113A,BLVRA,GALNT7,CASP4,PTPRF,HLA-B,NAAA,RPL12,RBM47,DGCR2,PEX2,SYT13,HOXC13 |
| 2.182e-03 | -6.13 | CYCLIN_D1_KE_.V1_UP | MSigDB lists | CYCLIN_D1_KE_.V1_UP | 186 | 42 | 17758 | 2588 |
CASP3,HSPG2,FAM189A2,DAP,DCAF7,RASSF7,COL18A1,EGR3,PKN1,S100A2,DUSP5,CDS1,ZYX,PFKL,RGS3,TFAP2A,GOT1,KIF22,PLCB2,ALDH3A2,PHKG2,MGAT5,PIGC,BCL9,PTPRH,FHL2,KLK6,DUSP4,KCTD2,MAN2A2,MMP15,HSF4,ETS2,CGREF1,FAM3C,RAB31,GLB1,NRG1,DMWD,FZD5,AHR,CTBP1 |
| 2.182e-03 | -6.13 | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN | 186 | 42 | 17758 | 2588 |
SORT1,CCDC109B,FAM134A,PPFIBP2,SELL,KCTD12,NUCB2,NTAN1,KBTBD11,MERTK,BCAP31,LGALS3BP,GNS,APLP2,RB1,TYMP,OPN3,DRAM1,CITED2,SPRY2,SYK,PDGFC,MPP1,VAMP3,PYGL,DIAPH2,ERP44,TCF7,FOS,IDH1,TP53I3,MAGED2,SERPINA1,SPINT2,DYSF,GLB1,CTSA,LTBP2,APBA2,ST3GAL1,SLC31A2,ABCG1 |
| 2.182e-03 | -6.13 | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 186 | 42 | 17758 | 2588 |
ANXA3,LTBP1,GCLM,TRIM2,FARP1,SSH1,ZCCHC24,BACE1,ASL,PDGFRL,PLXNA1,ARHGEF40,PHLDA1,SRPX2,PPP2R3A,CALR,SS18,TGFBR3,RPS6KA2,IMPAD1,DACT1,RRBP1,TPST1,TWIST1,TNFRSF12A,TFG,CRTAP,OLFML2A,COL6A2,SPA17,MEST,MCFD2,GLT8D2,PDHX,SLC25A4,UAP1,KCNK1,NGFRAP1,DNM1L,LRIG1,TLE1,SLC31A2 |
| 2.182e-03 | -6.13 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | 186 | 42 | 17758 | 2588 |
CCNE2,MTM1,DEPDC1,KCTD12,DDR1,PSIP1,SDF4,KCTD9,AIM1L,FAM46A,P4HB,OSBPL3,PLK4,WWP1,BUB1,USP1,WBP4,MYBL1,TMX1,SMC4,METAP2,GFPT1,ENPP4,KIAA1841,FIGNL1,SEPT6,PBK,PLAUR,DPP9,PDE5A,GGH,ERP44,PIF1,ANLN,FAM64A,DDOST,NEIL3,NAB2,STK39,DONSON,ETAA1,PSMC1 |
| 2.182e-03 | -6.13 | GSE29618_PDC_VS_MDC_UP | MSigDB lists | GSE29618_PDC_VS_MDC_UP | 186 | 42 | 17758 | 2588 |
LAMP1,RUNX2,HSP90B1,CRYM,ATP8A1,CTSB,NUCB2,SLC20A1,ETS1,DUSP5,DAPK2,RAB15,ENTPD4,RPS6KA2,CTSC,RIMS3,RRBP1,UBE2J1,TSPAN13,EGLN3,LMAN1,ITM2C,SCYL3,SEPHS1,SEC61B,PFKFB2,RNF11,SYNE2,MYBL2,NPC2,CYFIP2,LHFPL2,CDK5R1,C18orf8,MAPKAPK2,PIAS3,SCARB2,DCK,CCDC69,IRF7,ARHGAP4,TBC1D4 |
| 2.182e-03 | -6.13 | TM4_1 | prosite domains | PS00421 | 21 | 9 | 11866 | 1802 |
CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN1,CD81,TSPAN17,TSPAN7 |
| 2.183e-03 | -6.13 | Inositol phosphate metabolism | REACTOME pathways | R-HSA-1483249 | 46 | 15 | 8202 | 1235 |
CALM2,PLCH1,PLCG1,INPPL1,PTEN,INPP5D,OCRL,PLCG2,CALM1,INPP4B,CALM3,ISYNA1,MINPP1,ITPKA,PLCB2 |
| 2.185e-03 | -6.13 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline | biological process | GO:0018401 | 5 | 4 | 16441 | 2455 |
EGLN3,P4HB,P4HA2,EGLN1 |
| 2.190e-03 | -6.12 | GROSS_HYPOXIA_VIA_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_HIF1A_DN | 106 | 27 | 17758 | 2588 |
CPD,LMO7,POU6F1,SOAT1,TGIF1,ENO2,DAP,VWA1,IL18,PIM3,MERTK,FOS,SSX2IP,KLHL2,PGF,ACAP2,CTGF,CYR61,ZFP36,NFKBIA,SH3BP4,PRKCDBP,GYS1,SGK1,SPRY2,S100A13,CAPN1 |
| 2.190e-03 | -6.12 | LE_EGR2_TARGETS_DN | MSigDB lists | LE_EGR2_TARGETS_DN | 106 | 27 | 17758 | 2588 |
UGT8,MBP,CD55,NDRG1,PIK3R1,UTRN,FTH1,PIM3,EMP2,CMTM6,CHST2,MAPK8IP1,PRX,KCNK1,FAAH,TMEM30A,FUT8,ABCB1,CD9,ABCA2,LIMCH1,NR4A2,AK3,TIPARP,CPEB2,CERS2,SEMA3B |
| 2.199e-03 | -6.12 | RNA polymerase II core promoter sequence-specific DNA binding | molecular function | GO:0000979 | 51 | 16 | 16491 | 2452 |
RUNX2,PAX6,SUZ12,TP53,GATA3,FOS,GBX2,STAT6,MITF,TFAP2A,STAT1,NLRC5,H2AFY,IRF7,NR4A2,SOX8 |
| 2.206e-03 | -6.12 | positive regulation of cell differentiation | biological process | GO:0045597 | 796 | 148 | 16441 | 2455 |
ACVR1,EPHA4,RET,GATA3,MORF4L2,CAMK1D,LTBP3,GRM5,TP73,CTNNB1,CTGF,NPNT,CDKL5,IL6ST,DNM2,TACSTD2,PACSIN1,TIAM1,RASGRP1,LOXL2,SAV1,POR,RHEB,IRX3,DPYSL3,GPRC5B,LIMK1,TBX1,ITPKA,GRN,RUNX2,SERPINE2,LGALS3,SOX9,ETV5,MECOM,BMP2,CALR,RB1,ITGA3,CA2,CYR61,FAM20C,GATA2,MEGF8,SUCO,PRKCI,TNFRSF12A,NPTN,C10orf54,NTN1,WNT3A,RIMS2,SOCS5,EPB41L5,MMD,HMG20B,PDE5A,KIF20B,ILK,GNAS,NCOA3,SEMA4D,SETD3,TMEM30A,CSF1,AURKA,ARPC2,MAP3K5,SEMA3A,RPS6KA3,EHD1,FOXO6,NF2,IL15,THRA,INPP5D,RPS6KA1,EGR3,TNFSF9,CD46,DACT1,SMO,BCL6,TWIST1,DAB2IP,TMEM64,TIMP2,AKT1,RIPK2,DMTN,SOCS3,ARHGAP35,HSF4,PTGS2,FYN,BHLHB9,AXL,PTK7,WWTR1,TRIOBP,NRG1,EFNA5,KLF5,RGS14,COBL,ARNT,MAPK12,BIN1,CTHRC1,ARHGEF7,FLOT1,GDF15,CRABP2,ETS1,TEAD3,NEO1,CTNNBIP1,BMP7,BAX,H2AFY,MAPK11,RAG1,GFI1,SYK,TLE6,FAM134C,TGIF1,HES1,RHOA,WNT10B,RAPGEF2,ASPM,RGCC,FOS,CD83,MAP1B,BTG1,PROM1,ACVRL1,FGF18,PPP2R3C,GPER1,SOX8,ARSB,SHOX2,L1CAM,FOXA1 |
| 2.210e-03 | -6.11 | soft_tissue-blood_vessel-haemangioma | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma | 18 | 8 | 17775 | 2585 |
TSC1,PLCG1,CTNNB1,AKT1,PTEN,PIK3CA,TP53,IDH1 |
| 2.210e-03 | -6.11 | meningothelial | COSMIC cancer mutations | meningothelial | 18 | 8 | 17775 | 2585 |
CDKN2C,RB1,NF2,AKT1,PTEN,SMO,PIK3CA,EGFR |
| 2.210e-03 | -6.11 | meninges-meningioma-meningothelial | COSMIC cancer mutations | meninges-meningioma-meningothelial | 18 | 8 | 17775 | 2585 |
CDKN2C,RB1,NF2,AKT1,PTEN,SMO,PIK3CA,EGFR |
| 2.210e-03 | -6.11 | pituitary | COSMIC cancer mutations | pituitary | 428 | 84 | 17775 | 2585 |
LMO7,NF2,DNAJC3,RET,EPHX4,TP53,KIF2C,PLXNA1,BARD1,PDGFA,CDKN2C,ADPRHL1,CTNNB1,CDH1,KCNS3,PIK3CA,ODF2L,NAGA,SULF2,AKT1,UTRN,SERTAD3,TEP1,NBPF3,KIF1C,SLC11A2,KIF13A,IDH1,VCP,SLC44A3,RBM47,PDLIM3,UEVLD,LIMK1,PNPLA6,DHTKD1,RNASEL,ARF6,WBSCR27,BTBD6,PPP2R5D,KDELC2,PRKAR1A,WASF3,DYRK3,TAOK2,ALDH6A1,CCM2,SLC36A4,COL4A5,ZNF219,RSAD1,SPP1,RB1,TAF1B,ITGA3,ATP8B1,MOXD1,ZNF117,NUP85,MYO5A,MED22,ABCC1,PIGC,ADAMTS2,DUSP23,PIP4K2C,OGDHL,PGBD1,PDK3,YES1,AKAP3,PKM,BCAR1,EGFR,GNAS,HTT,PELI2,ZFP30,KBTBD2,APPL2,ARRB1,NR4A2,CDAN1 |
| 2.212e-03 | -6.11 | MULTICELLULAR_ORGANISMAL_DEVELOPMENT | MSigDB lists | MULTICELLULAR_ORGANISMAL_DEVELOPMENT | 1020 | 181 | 17758 | 2588 |
DOC2A,GAA,UGT8,ACVR1,AGRN,RET,PLAC1,IL18,PLXNA1,DNER,CHST2,PICK1,NPM2,TGFBR3,CTGF,SHC3,DPYSL2,FOSB,IL31RA,PAPSS1,KLF3,ARNT2,SGCE,SOD1,ARHGDIB,ZBTB7B,COL12A1,DPYSL3,MDK,HLF,KCNMB4,DNM1L,TBX1,HOXA9,LIMK1,BMP1,SERPINI1,TMOD2,POMT1,APBA2,NRGN,PPP2R5D,NR2C2,FGD1,RUNX2,RACGAP1,NOTCH2,NCKAP1,APBA1,HPCAL4,ELF3,TFAP4,BMP2,OSTF1,TNFRSF12A,NPTN,PIM1,ETV7,MYLIP,ALDH3A2,MDFI,SOCS5,DPYSL5,UFD1L,KLK5,PCDH1,GYLTL1B,NPHP3,MEST,DPYSL4,RASA1,RHOB,CDK5R1,INSR,ETS2,HTT,TIMM8A,COL13A1,CSF1,ITGA7,NAB2,ALPK3,EGFL7,KLK7,GDF11,DRP2,SHROOM2,APOL2,RARG,RPS6KA3,MTM1,PAX6,PAPSS2,NF2,TP53,COL18A1,ERBB2,IRX4,MRAS,EGR3,EXT2,MXD1,ARTN,LMO4,LHX6,TWIST1,EPHB4,F2R,FLOT2,DVL2,SEMA3B,MBP,UTRN,HTATIP2,ALDH5A1,RTN4RL1,PAFAH1B3,SHROOM3,NGFRAP1,WFS1,SECTM1,TLE1,EFNA5,MAPK12,GCLM,NKX3-1,DYRK3,PCOLCE,JRKL,CIT,CCM2,PBX3,AES,JAG2,CRABP2,ETS1,GSTP1,HOXB2,FGF19,FZD6,NRP2,HDAC9,RND1,CTNNBIP1,FOXP2,ADORA1,PTEN,BAX,TFAP2A,CD9,ARVCF,TRIM3,ERCC2,RAG1,CITED2,SGCB,SPRY2,SYK,FARP2,POU6F1,PDGFC,TGIF1,HES1,GCLC,STMN3,COL7A1,LEPR,BCL10,PITX2,BTG1,DGCR2,CTNS,ACVRL1,SCG2,ERAP1,PKD2,HOXB13,SOX8,SHOX2,L1CAM,JARID2 |
| 2.214e-03 | -6.11 | coated vesicle | cellular component | GO:0030135 | 229 | 50 | 17570 | 2579 |
SORT1,SLC2A4,GPR107,HLA-E,HLA-F,CTSZ,TGOLN2,SNX9,BCAP31,HLA-A,AP1M2,CTSC,SNX18,OCRL,LMAN2L,FCHO1,STEAP2,DNM2,CD9,ECE1,HLA-C,LMAN1,PACSIN1,RAB27B,GAD1,TMED2,DVL2,KDELR1,SEC23A,VPS11,FZD4,DENND1B,VAMP3,FURIN,COL7A1,FAM109A,MCFD2,C3orf58,EGFR,EPN3,HLA-B,LDLRAP1,SERPINA1,AREG,HTT,WIPI1,SH3BP4,FZD5,NRGN,COPG1 |
| 2.225e-03 | -6.11 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | 71 | 20 | 17758 | 2588 |
PLA2G4A,CD99,NFE2L3,HES1,LGALS3,ITCH,FXYD3,RHPN2,H2AFV,NFIB,CD83,ELF3,CTSC,A4GALT,FAM3C,IRF7,MDFIC,IFIT1,AHR,S100A13 |
| 2.225e-03 | -6.11 | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | MSigDB lists | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | 71 | 20 | 17758 | 2588 |
BMF,COL6A2,HAPLN3,LRRC66,LGI3,COL7A1,DDR1,ADRBK2,LGALS3BP,SH2D4A,PTPRF,CYR61,ANKS1B,PTK7,BMP1,SMO,PIM1,F2R,L1CAM,TSPAN33 |
| 2.227e-03 | -6.11 | Asparagine N-linked glycosylation | REACTOME pathways | R-HSA-446203 | 181 | 42 | 8202 | 1235 |
CMAS,TRAPPC10,MAN1A2,GNE,PDIA3,CTSZ,NANS,B4GALT4,CALR,NAPG,MGAT1,CTSC,ALG13,MGAT4A,LMAN2L,FUT8,RPN2,TFG,LMAN1,SLC35A1,PPP6R1,MGAT5,TMED2,GFPT1,SEC23A,MLEC,MGAT4B,COL7A1,SLC17A5,MCFD2,MAN2A2,FUCA1,UAP1,DDOST,SERPINA1,AREG,DOLPP1,GLB1,CTSA,ALG2,B4GALT3,ST3GAL1 |
| 2.230e-03 | -6.11 | KEGG_ENDOMETRIAL_CANCER | MSigDB lists | KEGG_ENDOMETRIAL_CANCER | 52 | 16 | 17758 | 2588 |
AKT1,CASP9,PIK3R1,TP53,ERBB2,TCF7,ILK,ELK1,APC2,EGFR,CCND1,CDH1,CTNNB1,PTEN,PIK3CA,PIK3CD |
| 2.230e-03 | -6.11 | TBK1.DN.48HRS_UP | MSigDB lists | TBK1.DN.48HRS_UP | 52 | 16 | 17758 | 2588 |
MLEC,PSRC1,CALM1,ARL4C,CALM3,SLC11A2,DDR1,LBR,APPBP2,CALM2,TM9SF2,FCHO1,MYLK,UBE2J1,PIK3C2B,ZMIZ1 |
| 2.239e-03 | -6.10 | morphogenesis of a branching structure | biological process | GO:0001763 | 182 | 42 | 16441 | 2455 |
ACVR1,NKX3-1,GRHL2,TMTC3,ST14,SOX9,CTSZ,PLXNA1,GBX2,BMP2,CTNNBIP1,CTNNB1,NPNT,BMP7,GPC3,DLG1,BAX,PPP1CA,SLC12A2,ETV4,SPRY2,DCHS1,TFAP2C,ILK,DAG1,EDNRA,SOCS3,NCOA3,FAT4,AREG,FGFR2,COL13A1,CSF1,SPINT2,PKD2,HOXB13,PLXND1,SOX8,FZD5,SEMA3A,FOXA1,ADAMTS16 |
| 2.241e-03 | -6.10 | MAHADEVAN_RESPONSE_TO_MP470_DN | MSigDB lists | MAHADEVAN_RESPONSE_TO_MP470_DN | 18 | 8 | 17758 | 2588 |
CYR61,SOD2,GDF15,CTTN,GEM,DUSP5,MAFF,DUSP1 |
| 2.241e-03 | -6.10 | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_UP | MSigDB lists | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_UP | 18 | 8 | 17758 | 2588 |
IGFBP6,ARRB1,TACSTD2,VSIG10,SCARA3,NDE1,NPDC1,SIRPA |
| 2.245e-03 | -6.10 | RB_P130_DN.V1_UP | MSigDB lists | RB_P130_DN.V1_UP | 127 | 31 | 17758 | 2588 |
RASGRF1,FADS2,SEMA6B,KIF20A,CHCHD7,CRB3,ADCK3,TRAF2,ABCG4,LITAF,SPATA13,STMN3,RACGAP1,MRAS,AURKB,FAM73B,B4GALT4,GRTP1,SNN,CDK1,CMTM7,IER3,SNTA1,CASP7,FAM64A,MYLK,AURKA,KIF22,CCNB2,UBE2C,PCSK5 |
| 2.246e-03 | -6.10 | perinuclear region of cytoplasm | cellular component | GO:0048471 | 615 | 116 | 17570 | 2579 |
LAMP1,SLC2A4,NF2,TRIP10,NDRG1,ARFGEF1,RHPN2,ERBB2,NDRG2,RASGRP3,PLA2G16,HDAC6,PRKACA,APC2,TRIM68,GNB2,PICK1,NCS1,PER2,CYHR1,RAB15,CDH1,CTNNB1,CTGF,WDR44,CABP1,OSBPL3,DLG1,DNM2,AKR1B1,ECE1,OSBPL7,TSPAN1,PACSIN1,MYRIP,FLOT2,S100A13,MX1,SEC23A,CAPN6,S100A4,DMTN,CDC20,EZR,PRKAR2B,SLC11A2,PRKRA,CDC25C,VCP,OPTN,STX10,DNM1L,STK26,ATP7B,STAT1,XRCC3,RAB29,ABCA1,COBL,PINK1,SORT1,HSP90B1,NFKBIE,ATP9A,RASA2,CTSB,HERC5,APBA1,LMNA,M6PR,CORO1B,KIF5B,CALR,CAPN2,SPP1,ITGA3,MLPH,RNF128,MAGEE1,CST3,PAK2,PLEKHF1,ABCD1,PIKFYVE,ITM2C,S100A6,CKAP4,P2RX4,MOB4,RAB3B,AMFR,RAPGEF2,PIK3R1,KIF20B,CYFIP2,MAPK8IP1,EGFR,CDK5R1,BCL10,GNAS,GALNT3,EPN3,CSF1,DBI,DGAT2,AURKA,GLB1,GPER1,ALG2,PLD1,MAL2,FZD5,NDFIP1,NRBP1,PTGES,TMEM173 |
| 2.248e-03 | -6.10 | pleomorphic_carcinoma | COSMIC cancer mutations | pleomorphic_carcinoma | 11 | 6 | 17775 | 2585 |
KIF5B,ERBB2,CTNNB1,EGFR,PIK3CA,TP53 |
| 2.251e-03 | -6.10 | morphogenesis of an epithelial sheet | biological process | GO:0002011 | 42 | 14 | 16441 | 2455 |
ARHGAP24,ADAM17,RHOA,PDCD10,CYR61,ACVRL1,MEGF8,FLRT3,MPP5,DDR1,HOXB2,DAG1,DVL2,LCP1 |
| 2.252e-03 | -6.10 | GRB7 events in ERBB2 signaling | REACTOME pathways | R-HSA-1306955 | 5 | 4 | 8202 | 1235 |
ERBB2,NRG2,NRG1,ERBB3 |
| 2.252e-03 | -6.10 | SMAC-mediated apoptotic response | REACTOME pathways | R-HSA-111469 | 5 | 4 | 8202 | 1235 |
CASP3,CASP7,CASP9,XIAP |
| 2.252e-03 | -6.10 | SMAC-mediated dissociation of IAP:caspase complexes | REACTOME pathways | R-HSA-111464 | 5 | 4 | 8202 | 1235 |
CASP3,CASP7,CASP9,XIAP |
| 2.252e-03 | -6.10 | SMAC binds to IAPs | REACTOME pathways | R-HSA-111463 | 5 | 4 | 8202 | 1235 |
CASP3,CASP7,CASP9,XIAP |
| 2.257e-03 | -6.09 | SERTA | pfam domains | PF06031 | 5 | 4 | 16629 | 2504 |
CDCA4,SERTAD2,SERTAD4,SERTAD3 |
| 2.260e-03 | -6.09 | proteolysis involved in cellular protein catabolic process | biological process | GO:0051603 | 499 | 98 | 16441 | 2455 |
FAF2,DNAJC3,PSME2,CUL4B,PTTG1,FBXO2,CUL1,UBE2Z,PSME1,MVB12B,CCNB1,HDAC6,RAD23A,PSMD1,KIF14,PSMC2,TINAGL1,LGMN,PLK1,SIRT1,SEC61B,ERLEC1,FBXL16,ITCH,USP18,RNF11,CDC20,VPS4B,RNF165,AURKB,CCNF,CBL,RNF19B,CDK1,VCP,ZMPSTE24,TRIM9,DNAJC10,IDE,PSMD3,WFS1,WWTR1,CHMP4B,AREL1,PSMC1,PINK1,HSP90B1,CIT,CTSB,JKAMP,DNAJB2,PSMD7,PSMD10,CTSZ,ZNRF3,FBXO6,DNAJB9,WWP2,CAPN2,RNF128,CTSC,FBXO7,NEK2,FBXL14,UBE2J1,PCYOX1,WWP1,USP38,USP1,STT3B,ZRANB1,MYLIP,PSMA5,UFD1L,USP31,PSMB4,AMFR,NUB1,UBE2A,FBXO9,FBXO8,TP53INP2,PSMA4,FBXO10,USP6,CTSL,CTSV,UBE2D2,AURKA,ARRB1,CTSA,YOD1,NDFIP1,UBE2C,RNF146,USP16,FBXW5,USP43 |
| 2.262e-03 | -6.09 | CFTR (cystic fibrosis transmembrane conductance regulator) | protein interactions | 1080 | 192 | 46 | 16036 | 2547 |
GRN,LMO7,LGALS3,LRRFIP2,PSME2,JKAMP,PRKAA1,EPS8,HDAC6,PRKACA,SNX9,REPS1,SLC9A3R2,BCAP31,RCN1,EPCAM,KIF5B,CDH1,RANBP1,PRKG1,SORL1,MARCH2,TFG,FLOT2,TIAM1,HSPA2,CLCN3,PLEKHA6,PSMB4,TCEB2,TMEM43,SEPT6,AMFR,EZR,EMC2,ESYT1,ERBB2IP,CBL,GNA11,VCP,TJP3,SLC9A6,RYK,SARAF,SH3BGRL2,HSPB1 |
| 2.264e-03 | -6.09 | TGFBR2 (transforming growth factor beta receptor II) | protein interactions | 7048 | 98 | 27 | 16036 | 2547 |
ACVR1,IQGAP1,ARHGEF7,PIK3R1,ERBB2,SCRIB,TGFBR1,RAB6A,CCNB1,CBL,SBF1,SPSB1,CDK1,ZFYVE9,NRP2,PTPRF,TGFBR3,CTNNB1,JAK1,WDR44,ACVRL1,PPP1CA,MAP3K7,OSR1,CCNB2,NDFIP1,OCLN |
| 2.265e-03 | -6.09 | GRADE_COLON_AND_RECTAL_CANCER_DN | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_DN | 96 | 25 | 17758 | 2588 |
NR3C1,GNPDA1,DHPS,GGA1,DAP,SERTAD4,CACNA2D2,OSGIN2,COL4A5,LDB2,ADAMTSL4,GNA11,HMGXB4,PARM1,B3GALNT1,TGFBR3,LYPD3,MITF,SLC30A6,TOX2,FHL1,PLD1,UNC5B,TLN2,GFI1 |
| 2.265e-03 | -6.09 | EIF4E_DN | MSigDB lists | EIF4E_DN | 96 | 25 | 17758 | 2588 |
LMO7,CD55,SORT1,TNIP1,FAM160B1,IQGAP1,ESRP1,DENND2D,APPBP2,FRMD4B,PRDX4,EPDR1,FAS,FUCA1,PTGS2,TRIM47,CTSC,SEMA4D,RCBTB2,PTER,TSPAN6,ALPK1,MAP3K5,LOXL1,CYP1B1 |
| 2.265e-03 | -6.09 | NAKAMURA_ADIPOGENESIS_LATE_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_LATE_UP | 96 | 25 | 17758 | 2588 |
ACACB,GCC2,ELK3,MMD,PRSS23,XYLT1,SERPINB9,PRKAR2B,GLT8D2,STX3,IL22RA1,CDKN2C,TFAP4,IRS2,TGFBR3,PPP2R5A,CTNNB1,RAB31,EFNA1,PPP1CA,NPTXR,ABCA1,GM2A,CYBRD1,CKS2 |
| 2.268e-03 | -6.09 | MODULE_45 | MSigDB lists | MODULE_45 | 565 | 107 | 17758 | 2588 |
S100A11,RPS6KA1,THRA,TSC22D3,INPP5D,TAP1,DGKA,SOD2,GMPR,NRG2,IL13RA1,IL27RA,TP53I11,SDC1,FLT3,CARD10,CYP26A1,IER3,DAPK2,ZYX,TYMP,SP100,TRANK1,TACC2,SH3BP1,LMO4,PLCG2,CAPG,BCL6,DNM2,ANKRD12,IFIT1,PIK3CD,NFKB2,PTPRE,IL1RAP,RASGRP1,CYP1B1,LAMP2,CPD,VPS11,CD55,PFKFB2,S100A4,PTPN9,CDA,ARHGDIB,CCNF,CASP4,LCP1,TBX1,STAT6,SECTM1,STAT1,BMP1,ARHGAP4,NRGN,SLC31A2,ABCA1,GRN,PCOLCE,ITGA6,ARL4C,SELL,ASAH1,PKN1,TRIB2,ITGA2B,M6PR,RAC2,CTSC,LLGL2,SLC16A6,CD22,FDXR,CADPS2,PIM1,PLCB2,DLX4,SYK,MMD,PLSCR1,WNT10B,MAPKAPK3,MPP1,STAT4,BTN3A2,EMP3,PYGL,TCF7,PRRC1,IFIT3,DPYSL4,CDK5R1,CD8A,SLC6A6,SERPINA1,RCBTB2,SEMA4D,NMI,ARAP1,RAB31,ZMIZ1,JAK3,SERPINB1,IRF1,XDH |
| 2.269e-03 | -6.09 | MORI_SMALL_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | MORI_SMALL_PRE_BII_LYMPHOCYTE_DN | 76 | 21 | 17758 | 2588 |
TUBB4B,ASXL1,STAT4,CRIP2,ISYNA1,SLC20A1,STIL,ABR,LCP1,ZYX,CDCA4,ATP1A1,CA2,RBL1,CTSC,FXYD5,RPN2,SGOL1,SMC4,EHD1,TUBA4A |
| 2.269e-03 | -6.09 | lentigo_maligna | COSMIC cancer mutations | lentigo_maligna | 30 | 11 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,FLT3,GNA11,EGFR |
| 2.269e-03 | -6.09 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_I | 30 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,SMO,PIK3CA,IDH1,GNA11,EGFR |
| 2.269e-03 | -6.09 | ovary-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | ovary-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 30 | 11 | 17775 | 2585 |
RB1,NF2,CTNNB1,AKT1,PTEN,MSH2,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 2.271e-03 | -6.09 | INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | INTRACELLULAR_PROTEIN_TRANSPORT | 143 | 34 | 17758 | 2588 |
NFKBIE,PEX6,GGA1,PDIA3,APBA1,BARD1,ERP29,ZFYVE9,APPBP2,ATG4A,CALR,ZFYVE16,AP1M2,CDH1,PPP1R10,KIF13B,BCL6,F2R,TRAM1,RPGR,KDELR1,MDFI,ATG4D,NAGPA,AKT1,COG2,STRADB,ICMT,VCP,OPTN,KLHL2,KPNA2,CTSA,LTBP2 |
| 2.273e-03 | -6.09 | HASEGAWA_TUMORIGENESIS_BY_RET_C634R | MSigDB lists | HASEGAWA_TUMORIGENESIS_BY_RET_C634R | 11 | 6 | 17758 | 2588 |
IRF7,IFIT1,DUSP4,USP18,RET,SERINC2 |
| 2.273e-03 | -6.09 | VACUOLAR_MEMBRANE | MSigDB lists | VACUOLAR_MEMBRANE | 11 | 6 | 17758 | 2588 |
LAMP2,SLC17A5,CTNS,CD63,LAMP3,ABCA2 |
| 2.273e-03 | -6.09 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | MSigDB lists | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | 11 | 6 | 17758 | 2588 |
CALM2,CALM3,DLG3,GRIK2,CALM1,DLG1 |
| 2.274e-03 | -6.09 | Furin_repeat | interpro domains | IPR006212 | 18 | 8 | 18293 | 2672 |
INSR,IGF1R,FRAS1,FURIN,ERBB2,ERBB3,EGFR,PCSK5 |
| 2.274e-03 | -6.09 | MHC_I_a_a1/a2 | interpro domains | IPR001039 | 18 | 8 | 18293 | 2672 |
HLA-B,MICB,HLA-E,HLA-F,RAET1L,HLA-C,ULBP2,HLA-A |
| 2.287e-03 | -6.08 | SIRNA_EIF4GI_UP | MSigDB lists | SIRNA_EIF4GI_UP | 91 | 24 | 17758 | 2588 |
SUN2,PMPCB,TCF25,ST13,NQO1,LAP3,INPP5D,FXYD3,PYGL,ASAH1,PSME1,ESYT1,SLC25A5,ECI1,DAG1,CORO1B,HLA-B,ATP1A1,CA2,CTSC,PAPSS1,DTX4,ALDH7A1,HSPB1 |
| 2.290e-03 | -6.08 | Apoptosis | REACTOME pathways | R-HSA-109581 | 160 | 38 | 8202 | 1235 |
CASP3,BMF,ADD1,PSME2,TRAF2,XIAP,TP53,PSMD7,PSMD10,PSME1,BCL2L1,BCAP31,LMNA,DAPK2,PSMD1,CTNNB1,CDH1,PAK2,PSMC2,DAPK1,BAX,PSMA5,PSMB4,AKT1,CASP9,PRKCQ,PSMA4,FAS,CASP7,FNTA,STK26,H1F0,DNM1L,PSMD3,E2F1,UNC5B,PSMC1,OCLN |
| 2.292e-03 | -6.08 | GNF2_INPP5D | MSigDB lists | GNF2_INPP5D | 43 | 14 | 17758 | 2588 |
HLA-B,TAPBP,RAC2,HLA-E,STAT6,INPP5D,HLA-F,TAP1,ARHGDIB,PSME1,HLA-C,GRK6,ARF6,HLA-A |
| 2.292e-03 | -6.08 | VANHARANTA_UTERINE_FIBROID_UP | MSigDB lists | VANHARANTA_UTERINE_FIBROID_UP | 43 | 14 | 17758 | 2588 |
CCND1,DDB2,FDXR,TFAP2C,TGOLN2,SPCS3,LTBP2,LOXL2,MEST,ITM2C,STARD13,ZFYVE9,EDNRA,IGSF3 |
| 2.292e-03 | -6.08 | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | MSigDB lists | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | 43 | 14 | 17758 | 2588 |
CASP3,PRODH,SLC25A4,DNM1L,NR4A1,CPT2,SIVA1,FDXR,SOD2,TP53,BAX,SERPINB5,BCL2L1,PLS3 |
| 2.292e-03 | -6.08 | PID_TCPTP_PATHWAY | MSigDB lists | PID_TCPTP_PATHWAY | 43 | 14 | 17758 | 2588 |
INSR,JAK1,STAT6,CSF1,PIK3R1,STAT1,PIK3CA,KPNA2,PIK3CD,LMAN1,JAK3,PDGFB,GAB1,EGFR |
| 2.292e-03 | -6.08 | ULE_SPLICING_VIA_NOVA2 | MSigDB lists | ULE_SPLICING_VIA_NOVA2 | 43 | 14 | 17758 | 2588 |
PTPRF,APLP2,CASK,AGRN,TACC2,GRIK2,SRR,GRIN1,CLSTN1,EFNA5,RAP1GAP,MAPK8IP1,CAMK2G,ATP2B1 |
| 2.292e-03 | -6.08 | REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE | MSigDB lists | REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE | 81 | 22 | 17758 | 2588 |
SIGIRR,RIPK2,TAB3,MAPKAPK3,RPS6KA1,PELI3,DUSP4,ELK1,FOS,CDK1,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 2.293e-03 | -6.08 | CD63 (CD63 molecule) | protein interactions | 967 | 24 | 10 | 16036 | 2547 |
LGALS3,TIMP1,LGALS8,CD82,ITGA6,CD9,PTGFRN,SDC1,CD81,FAM134C |
| 2.293e-03 | -6.08 | SPC24 (SPC24, NDC80 kinetochore complex component) | protein interactions | 147841 | 24 | 10 | 16036 | 2547 |
ZWINT,SPC25,ASPM,OTUD6B,NDC80,PLD2,NUF2,BUB1,SKA1,VCP |
| 2.297e-03 | -6.08 | KEGG_APOPTOSIS | MSigDB lists | KEGG_APOPTOSIS | 86 | 23 | 17758 | 2588 |
CASP3,AKT1,TRAF2,PIK3R1,CASP9,TP53,XIAP,PRKAR2B,BCL2L1,PRKACA,FAS,ENDOD1,IL1R1,CAPN2,CASP7,IRAK1,NFKBIA,PIK3CA,BAX,PIK3CD,IL1RAP,CAPN1,PRKAR1A |
| 2.298e-03 | -6.08 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP | 181 | 41 | 17758 | 2588 |
CMAS,SSH1,LFNG,PSME2,MMADHC,FBXO2,CDCA8,OSGIN2,GABRG2,KCTD12,IL18,IL27RA,ARHGEF16,ELF3,MARCH8,DAZAP1,TM9SF2,PTEN,ALG13,FOSB,PRC1,SORL1,AHCY,RAB27B,ALDH3A2,SMC4,DUSP1,DCAF6,MBP,CAPN6,KCTD20,SRSF5,BCL2L13,SLC25A5,CDK5R1,ZMPSTE24,FGFR2,PLK2,NR4A2,HIPK3,ABCG1 |
| 2.299e-03 | -6.08 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDM_UP | 192 | 43 | 17758 | 2588 |
CHCHD7,ATP8A1,FHDC1,C6orf106,RACGAP1,TEX2,TAF6L,CAMK1D,GPSM2,IFT27,APOBEC3B,RB1,ELMO2,N4BP3,MITF,TBCD,CDH3,PHKA2,ETHE1,PLCB2,TPCN1,CTDSP2,STAT4,SAT1,PDK3,RNF19B,IDH1,OSBPL2,HLA-B,RBM47,PRCP,NAT1,CDCA5,SECTM1,HDAC1,IRF7,PDXK,RGS14,NCAPG2,IFIH1,CBX7,PRR15,ABCG1 |
| 2.299e-03 | -6.08 | GSE17721_LPS_VS_PAM3CSK4_12H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_12H_BMDM_UP | 192 | 43 | 17758 | 2588 |
CASP3,KLK10,TXN,NFKBIE,SERPINE2,DHPS,PSME2,SDC4,PSME1,CD274,KREMEN1,LGALS3BP,DOPEY2,WDFY1,CYP1A1,SH3BP1,FUT8,CST3,SGK1,TNPO2,TAGLN2,NOTCH3,LAP3,HMG20B,KIAA1109,PDK3,RAB3IP,ASB13,RNPEP,SP4,ENDOD1,SCARB2,CASP7,UAP1,NR1D2,GNPTAB,PLK2,TMEM30A,NFKBIA,ABCB1,NR4A2,NRBP1,CPEB2 |
| 2.299e-03 | -6.08 | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_DN | MSigDB lists | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_DN | 192 | 43 | 17758 | 2588 |
SPRED1,NFKBIE,FAM189A2,TRAPPC10,NLRX1,ATP9A,CD82,FLYWCH2,RASSF7,PBX3,ECI1,CMTM6,CHPF,ZYX,PIK3AP1,DPYSL2,KCNK5,PPP1R16A,AIM1,DRAM1,BAX,MINPP1,C9orf72,PSMB4,WNT10B,SH3BGRL,KIF20B,TNFAIP8L1,NEURL1B,BORA,VCP,SEC14L2,DHX32,DGKH,TMEM30A,HDAC1,ARFGAP3,EGFL7,NR4A2,PPP2R3C,NDE1,SERPINB1,RARG |
| 2.299e-03 | -6.08 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | 192 | 43 | 17758 | 2588 |
CD99,TMEM184B,VANGL1,CAST,DGKQ,MCTP2,EFHD2,PLA2G16,SYTL2,WWP2,CAPN2,TGFBR3,PIK3AP1,CTSC,RGS3,PPP4R1,CNNM4,RASGEF1A,PDIA6,MYBL1,C12orf75,APOBEC3G,SYTL3,CXXC5,MBP,KIAA1841,PQLC3,PRSS23,MICB,S100A4,SNTB2,SYNE2,DIAPH2,FAS,ARHGAP35,OPTN,FYN,WIPI1,PITPNA,PIEZO1,SLC27A3,STARD3NL,CTDSP1 |
| 2.299e-03 | -6.08 | GSE17721_CTRL_VS_CPG_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_12H_BMDM_DN | 192 | 43 | 17758 | 2588 |
LZTFL1,PARP14,SERPINB9,SOD2,NDRG2,IL18,BLCAP,SLC1A3,CCNL1,INTS8,DNER,HOXB2,TNFSF9,KTN1,REPS1,APPBP2,LMO4,H2AFY,SNX16,CD70,IGFBP2,CTTN,PIM1,TSPAN33,CPD,MX1,GFPT1,SYPL1,PMPCB,FBLN5,RIPK2,TESK1,NUB1,CYS1,RAB3IP,PSMA4,CNOT2,PVRL2,GDE1,HOXA9,ZDHHC20,HDAC1,E2F8 |
| 2.299e-03 | -6.08 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP | 192 | 43 | 17758 | 2588 |
MAN2B2,SIGIRR,ENO2,MRPS15,BLVRB,GATA3,IL27RA,NUCB2,PKN1,LTBP3,RSAD1,M6PR,ZYX,PSMD1,TIMP1,TBCD,IL17RA,FAM102A,KIF22,CITED2,TIAM1,IFITM3,SEPT6,S100A4,PIK3R1,MAP3K6,PLEKHB1,OPTN,ATP13A2,SOCS3,TXK,ATP1A1,LDLRAP1,SEMA4D,NGFRAP1,PRDX3,INPP4B,AGBL5,CABIN1,NDFIP1,RTN3,TOB1,NRBP1 |
| 2.299e-03 | -6.08 | GSE17721_CTRL_VS_CPG_0.5H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_0.5H_BMDM_UP | 192 | 43 | 17758 | 2588 |
ADD1,AGRN,THRA,ITGA6,PTTG1,KIF23,ASAH1,INTS8,OAT,LBR,EFNB1,WDFY1,TM9SF2,EFR3A,MAGEE1,FAM20B,TNPO2,TACSTD2,STT3B,ETHE1,RCAN3,DGKG,SLC35A1,RPGR,NUP85,HP1BP3,QSOX1,GCA,ASXL1,PIP4K2C,NUSAP1,MCFD2,B3GALNT2,DOCK5,DGKE,AMMECR1,TBX18,RHOBTB2,TMOD2,CHMP4B,ABCA1,MYL12B,FAM134B |
| 2.300e-03 | -6.07 | mesonephric epithelium development | biological process | GO:0072163 | 89 | 24 | 16441 | 2455 |
HES1,FMN1,RET,SOX9,DCHS1,SDC4,GATA3,ILK,SDC1,EPCAM,BMP2,CTNNBIP1,FAT4,CTNNB1,FGFR2,NPNT,GPC3,BMP7,DLG1,PKD2,TACSTD2,GDF11,OSR1,ADAMTS16 |
| 2.300e-03 | -6.07 | mesonephric tubule development | biological process | GO:0072164 | 89 | 24 | 16441 | 2455 |
HES1,FMN1,RET,SOX9,DCHS1,SDC4,GATA3,ILK,SDC1,EPCAM,BMP2,CTNNBIP1,FAT4,CTNNB1,FGFR2,NPNT,GPC3,BMP7,DLG1,PKD2,TACSTD2,GDF11,OSR1,ADAMTS16 |
| 2.302e-03 | -6.07 | negative regulation of cell morphogenesis involved in differentiation | biological process | GO:0010771 | 109 | 28 | 16441 | 2455 |
SEMA6B,RHOA,MFI2,DMTN,CIT,RAPGEF2,LRP4,FBLN1,ULK2,CDK5R1,SPP1,AP1AR,SEMA4D,PTEN,CORO1C,VASN,STAT1,DAB2IP,TACSTD2,SEMA3G,EFNA1,WNT3A,NTN1,SEMA3A,TRIM62,FOXA1,NGEF,SEMA3B |
| 2.304e-03 | -6.07 | WINTER_HYPOXIA_METAGENE | MSigDB lists | WINTER_HYPOXIA_METAGENE | 231 | 50 | 17758 | 2588 |
CD99,TXN,NDRG1,BIK,TP53,COL4A5,BCL2L1,SLC20A1,PDGFB,ETS1,SIRPA,ICAM1,ELF3,HDAC9,SPP1,PFKL,CALD1,BHLHE41,ALDH1A3,CDKN1B,SORL1,IGFBP2,AK3,PIM1,CTSD,NFKB2,CITED2,QSOX1,PGM1,VPS11,NR3C1,NR4A1,PLAUR,SAT1,PPARA,BNIP3L,PDK3,FOS,CDK1,PGF,BTG1,PTGS2,SLC6A6,PLOD2,SYT7,P4HA2,ABCB1,HDAC1,EFNA1,RNASEL |
| 2.308e-03 | -6.07 | REACTOME_HS_GAG_BIOSYNTHESIS | MSigDB lists | REACTOME_HS_GAG_BIOSYNTHESIS | 30 | 11 | 17758 | 2588 |
HS6ST1,AGRN,HSPG2,GPC3,SDC4,HS3ST3B1,SDC1,NDST3,EXT2,GLCE,HS6ST3 |
| 2.308e-03 | -6.07 | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | 30 | 11 | 17758 | 2588 |
IGFBP6,SEMA4D,NDRG1,BIK,LITAF,PIM1,PKN1,IDH1,RARG,IRF1,IER3 |
| 2.308e-03 | -6.07 | KIM_LRRC3B_TARGETS | MSigDB lists | KIM_LRRC3B_TARGETS | 30 | 11 | 17758 | 2588 |
HLA-B,TAPBP,SERPINA1,PSME2,HLA-E,TAP1,FTH1,IFIT1,HLA-C,HLA-A,GM2A |
| 2.310e-03 | -6.07 | MAPK signaling pathway | KEGG pathways | ko04010 | 255 | 57 | 6908 | 1076 |
ELK4,PLA2G4A,CASP3,TAOK2,TRAF2,RPS6KA1,RASA2,TP53,CACNA2D2,TGFBR1,MRAS,RASGRP3,PRKACA,PDGFB,CACNB4,FGF19,DUSP5,MECOM,PDGFA,RAC2,RPS6KA2,PAK2,DUSP10,MAPK11,CACNA1D,MAP3K7,NFKB2,MAPK7,HSPA2,RASGRP1,DUSP1,MAP3K3,RASGRF1,AKT1,MAPKAPK3,NR4A1,RAPGEF2,DUSP4,ELK1,FOS,MAP3K6,MAPK8IP1,RASA1,EGFR,RASGRP2,FAS,MAPKAPK2,IL1R1,FGFR2,FGF18,MAP3K11,ARRB1,MAPK13,MAP3K5,HSPB1,RPS6KA3,MAPK12 |
| 2.310e-03 | -6.07 | MAPK signaling pathway | KEGG pathways | hsa04010 | 255 | 57 | 6908 | 1076 |
ELK4,PLA2G4A,CASP3,TAOK2,RASA2,TRAF2,RPS6KA1,TP53,CACNA2D2,TGFBR1,MRAS,RASGRP3,CACNB4,PDGFB,PRKACA,DUSP5,FGF19,MECOM,PDGFA,RAC2,RPS6KA2,PAK2,DUSP10,MAPK11,CACNA1D,NFKB2,MAP3K7,MAPK7,HSPA2,RASGRP1,DUSP1,MAP3K3,RASGRF1,AKT1,MAPKAPK3,NR4A1,RAPGEF2,DUSP4,ELK1,FOS,MAP3K6,MAPK8IP1,EGFR,RASA1,RASGRP2,FAS,MAPKAPK2,IL1R1,FGFR2,FGF18,MAP3K11,ARRB1,MAPK13,MAP3K5,HSPB1,RPS6KA3,MAPK12 |
| 2.317e-03 | -6.07 | - | gene3d domains | 1.25.40.10 | 194 | 46 | 9988 | 1574 |
TTC8,TCF25,TTC39B,ST13,TMTC3,P3H2,DNAJC3,KLC2,ERCC6L,WDTC1,TRAPPC8,GPSM2,AIP,APPBP2,TTC21B,NAPG,TRANK1,NOXA1,FICD,KLC3,IFIT1,VPS11,TMTC1,LONRF3,CFAP46,TTC7A,EMC2,TMTC2,CCNF,IFIT3,NPHP3,TANC1,UNC45B,SPAG1,RGPD5,PEX5,KIAA0141,TTC12,PSMD3,P4HA2,P4HA3,WDR19,CABIN1,TTC9,TTC39C,TANC2 |
| 2.318e-03 | -6.07 | neural tube formation | biological process | GO:0001841 | 104 | 27 | 16441 | 2455 |
TGIF1,CTHRC1,GRHL2,SALL4,ST14,SDC4,RAB23,PRICKLE1,KIF20B,SCRIB,NCKAP1,PRKACA,STIL,FZD6,ARHGAP35,BCL10,TSC1,VASP,SHROOM3,PTK7,LMO4,SPINT2,TWIST1,MAP3K7,COBL,RARG,DVL2 |
| 2.319e-03 | -6.07 | V$ETS2_B | MSigDB lists | V$ETS2_B | 265 | 56 | 17758 | 2588 |
IER5L,CTHRC1,PAX6,ARAP3,PPP1R12A,GPR107,CAST,TSC22D3,TRMT2B,ITPR2,CAMK1D,DOCK11,APBA1,PSIP1,TEAD3,B4GALNT1,VASP,RGS12,RNF128,SHC3,RGS3,ATP5H,CDKN1B,TWIST1,DIXDC1,RAB20,DAB2IP,KLF9,CACNA1D,SCN2A,CITED2,RBMS2,DOCK4,TAF5,PCDH1,FURIN,ARHGDIB,LDB2,ZBTB7B,PNKD,SPNS3,LCP1,MAPKAPK2,PGF,CRTC2,TMEM164,PLEKHH2,FYN,KLF12,CORO1C,MAP3K11,ARAP1,AGBL5,ARHGAP4,STARD13,LIFR |
| 2.322e-03 | -6.07 | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | MSigDB lists | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | 122 | 30 | 17758 | 2588 |
TRIM24,AKT1,NR4A1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,PHLPP1,ITPR3,CBL,PRKACA,CDK1,FGF19,CALM2,PLCG1,ADRBK1,PTEN,CNTRL,FGFR2,FGF18,STAT1,PIK3CA,CDKN1B,SPRY2,GAB1,FGFR1OP2,FRS3,PRKAR1A |
| 2.327e-03 | -6.06 | regulation of axonogenesis | biological process | GO:0050770 | 161 | 38 | 16441 | 2455 |
SEMA6B,SSH1,LRP4,RET,EPHA4,PLXNA1,CRABP2,SPP1,PTEN,CDKL5,DPYSL2,MEGF8,KIF13B,DNM2,TNFRSF12A,CTTN,SEMA3G,WNT3A,NTN1,TIAM1,SEMA3B,SSH3,RHOA,GRIN1,ILK,CDK5R1,ULK2,MAP1B,SEMA4D,LIMK1,SIPA1L1,NRG1,EFNA5,PLXND1,EFNA1,SHOX2,SEMA3A,L1CAM |
| 2.329e-03 | -6.06 | Growth_fac_rcpt_N_dom | interpro domains | IPR009030 | 127 | 31 | 18293 | 2672 |
LTBP1,FBLN5,IGFBP6,CELSR2,LRP4,FURIN,ERBB2,EPHA1,NOTCH2,JAG2,DNER,FBLN1,LTBP3,EGFR,NOV,INSR,IGF1R,FAT4,CTGF,CYR61,NPNT,FRAS1,MATN2,BMP1,EGFL7,IGFBP2,ERBB3,EPHB4,LTBP2,NOTCH3,PCSK5 |
| 2.330e-03 | -6.06 | antigen processing and presentation of exogenous antigen | biological process | GO:0019884 | 177 | 41 | 16441 | 2455 |
UNC93B1,KIF3C,SEC61G,HLA-E,PSME2,HLA-F,KLC2,PSMD7,TAP1,PDIA3,KIF23,PSMD10,RACGAP1,PSME1,KIF2C,KIF26A,HLA-A,CALR,PSMD1,AP1M2,PSMC2,DNM2,KIF22,HLA-C,CTSD,LGMN,PSMA5,SEC23A,SEC61B,PSMB4,KIF11,PSMA4,CTSL,DCTN6,HLA-B,TAPBP,PSMD3,CTSV,ITGAV,CENPE,PSMC1 |
| 2.330e-03 | -6.06 | SERTA | prosite domains | PS51053 | 5 | 4 | 11866 | 1802 |
SERTAD2,CDCA4,SERTAD4,SERTAD3 |
| 2.330e-03 | -6.06 | ACB_1 | prosite domains | PS00880 | 5 | 4 | 11866 | 1802 |
ACBD5,ECI2,ACBD3,DBI |
| 2.335e-03 | -6.06 | CH-domain | interpro domains | IPR001715 | 76 | 21 | 18293 | 2672 |
GAS2L1,LMO7,CAMSAP3,SPEF2,ASPM,ARHGEF7,IQGAP1,SYNE2,UTRN,PLS1,MICALL2,SPTB,LCP1,PLS3,SMTNL2,CLMN,SPTBN5,DIXDC1,LIMCH1,TAGLN2,IQGAP3 |
| 2.335e-03 | -6.06 | ANATOMICAL_STRUCTURE_DEVELOPMENT | MSigDB lists | ANATOMICAL_STRUCTURE_DEVELOPMENT | 990 | 176 | 17758 | 2588 |
DOC2A,GAA,ACVR1,UGT8,AGRN,SSH1,RET,GATA3,IL18,PLAC1,DNER,PICK1,CTGF,SHC3,DPYSL2,IL31RA,PAPSS1,DLG1,ARNT2,RCAN3,SGCE,SOD1,NFE2L1,ZBTB7B,COL12A1,DPYSL3,MDK,KCNMB4,TBX1,LIMK1,BMP1,SERPINI1,TMOD2,ARF6,APBA2,NRGN,PPP2R5D,HOXC13,NR2C2,FGD1,ARAP3,RUNX2,RACGAP1,NOTCH2,NCKAP1,APBA1,HPCAL4,ELF3,BMP2,CYR61,PRKCI,OSTF1,NPTN,ETV7,MYLIP,ALDH3A2,CCDC88A,SOCS5,DPYSL5,UFD1L,PCDH1,KLK5,GYLTL1B,WHSC1,MEST,NPHP3,DPYSL4,RASA1,RHOB,CDK5R1,SOX13,ETS2,HTT,TIMM8A,COL13A1,CSF1,ITGA7,NAB2,ARAP1,ALPK3,FGD6,EGFL7,KLK7,GDF11,DRP2,SHROOM2,RPS6KA3,MTM1,PAX6,PAPSS2,NF2,IRX4,COL18A1,ERBB2,MRAS,EGR3,EXT2,IER3,ARTN,LMO4,LHX6,TWIST1,NOTCH3,EPHB4,F2R,FLOT2,DVL2,SEMA3B,MBP,UTRN,HTATIP2,DUOX1,RTN4RL1,ALDH5A1,PAFAH1B3,SHROOM3,WFS1,SECTM1,TLE1,EFNA5,MAPK12,GCLM,DYRK3,TAOK2,JRKL,CIT,CCM2,PBX3,AES,JAG2,CRABP2,GSTP1,ETS1,FGF19,NRP2,RND1,SCML1,HDAC9,FOXP2,ANK1,ADORA1,PTEN,GPC3,CD9,TFAP2A,BAX,TRIM3,ERCC2,CITED2,RAG1,SGCB,SPRY2,SYK,FARP2,POU6F1,HES1,PDGFC,GCLC,STMN3,COL7A1,BCL10,PITX2,BTG1,CTNS,DGCR2,SCG2,ACVRL1,FGF18,ERAP1,PKD2,HOXB13,SOX8,FZD5,SHOX2,L1CAM,JARID2 |
| 2.348e-03 | -6.05 | filopodium membrane | cellular component | GO:0031527 | 18 | 8 | 17570 | 2579 |
VASP,ITGA3,NF2,SYNE2,UTRN,ITGAV,ARF6,ANTXR1 |
| 2.350e-03 | -6.05 | CHANDRAN_METASTASIS_DN | MSigDB lists | CHANDRAN_METASTASIS_DN | 288 | 60 | 17758 | 2588 |
MAN2B2,ILDR1,KLK10,SORBS1,RBM24,TSPAN15,LFNG,SCD5,MCTP2,FBXO2,ERBB2,AKAP17A,EGR3,PARM1,B3GALNT1,NOV,CTGF,ITGB8,KCNN4,NECAB3,ZFP36,BMP7,KLF3,FOSB,ALDH7A1,IGFBP2,CNOT6L,RAB27B,MOXD1,SMAGP,DUSP1,EPB41L5,MX1,PDGFC,TNIP1,NR4A1,TMEM98,PDE5A,TNS1,B3GALNT2,TXNDC11,FOS,CRISPLD2,FUCA1,MAGED2,DNAJC10,PTGS2,CACHD1,ZNF641,COL13A1,FGFR2,MYLK,SERPINB5,POMT1,PER3,STARD13,PDPR,CYBRD1,ANXA11,DEF6 |
| 2.351e-03 | -6.05 | RAO_BOUND_BY_SALL4 | MSigDB lists | RAO_BOUND_BY_SALL4 | 220 | 48 | 17758 | 2588 |
SPRED1,KLF2,DYRK3,TM2D2,TRIM2,TTC39B,TSPAN15,HEXB,TP53,RGS20,FAM91A1,IRF2BPL,WEE1,CTGF,IL6ST,FLRT3,FRYL,ZIC5,SLC44A1,CST3,TMEM64,TMEM8A,SPRY2,CCDC38,SULF2,MOB4,PDGFC,ZWINT,SNTB2,LYRM1,TFAP2C,AURKB,RAB38,PTGFRN,IDH1,RHOB,MAP1B,DGKH,DDAH1,FGFR2,STK38,SLC25A40,ZNF704,F2RL1,ARNT,COBL,JARID2,PHC1 |
| 2.352e-03 | -6.05 | receptor signaling protein serine/threonine kinase activity | molecular function | GO:0004702 | 70 | 20 | 16491 | 2452 |
MAP3K3,ACVR1,TAOK2,ACVR1C,MAPK4,TGFBR1,MAP3K6,EGFR,IRAK1,ACVRL1,MAP3K9,MAP3K11,KIAA1804,MAPK13,STK39,MAPK11,MAP3K7,MAPK7,MAP3K5,MAPK12 |
| 2.361e-03 | -6.05 | platelet dense tubular network | cellular component | GO:0031094 | 11 | 6 | 17570 | 2579 |
ITPR2,ITPR3,F2R,DMTN,ITPR1,EHD1 |
| 2.364e-03 | -6.05 | Sphingolipid signaling pathway | KEGG pathways | ko04071 | 120 | 31 | 6908 | 1076 |
RHOA,AKT1,TRAF2,PIK3R1,TP53,ASAH1,PLD2,SPTLC2,PPP2R3A,SGPP1,SGPL1,RAC2,FYN,ADORA1,PPP2R5A,PTEN,BAX,PIK3CA,PPP2R3C,MAPK11,MAPK13,PLD1,PIK3CD,MAP3K5,CTSD,PLCB2,PPP2R2D,PPP2R5D,ABCC1,MAPK12,CERS2 |
| 2.364e-03 | -6.05 | Sphingolipid signaling pathway | KEGG pathways | hsa04071 | 120 | 31 | 6908 | 1076 |
RHOA,AKT1,TRAF2,PIK3R1,TP53,ASAH1,PLD2,SPTLC2,PPP2R3A,SGPP1,SGPL1,RAC2,FYN,ADORA1,PPP2R5A,PTEN,BAX,PIK3CA,PPP2R3C,MAPK11,MAPK13,PLD1,PIK3CD,MAP3K5,CTSD,PLCB2,PPP2R2D,PPP2R5D,ABCC1,MAPK12,CERS2 |
| 2.366e-03 | -6.05 | central_nervous_system-thalamus-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-oligoastrocytoma_Grade_III | 22 | 9 | 17775 | 2585 |
BAG4,XYLT1,TP53,CSTF2,PYGO1,PHLDA1,RPS6KA3,MELK,PPP2R3A |
| 2.366e-03 | -6.05 | thymus | COSMIC cancer mutations | thymus | 22 | 9 | 17775 | 2585 |
SS18,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,EGFR |
| 2.366e-03 | -6.05 | endometrium-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | endometrium-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 22 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,MSH2,PIK3CA,TP53,FLT3,EGFR |
| 2.366e-03 | -6.05 | breast-hyperplasia-atypical_lobular_hyperplasia | COSMIC cancer mutations | breast-hyperplasia-atypical_lobular_hyperplasia | 26 | 10 | 17775 | 2585 |
CTNNB1,CDH1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 2.366e-03 | -6.05 | atypical_lobular_hyperplasia | COSMIC cancer mutations | atypical_lobular_hyperplasia | 26 | 10 | 17775 | 2585 |
CTNNB1,CDH1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 2.366e-03 | -6.05 | lung-carcinoma-acinar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-acinar_adenocarcinoma | 26 | 10 | 17775 | 2585 |
KIF5B,CTNNB1,AKT1,FGFR2,PTEN,SDC4,PIK3CA,TP53,ERBB2,EGFR |
| 2.381e-03 | -6.04 | occluding junction | cellular component | GO:0070160 | 111 | 28 | 17570 | 2579 |
DDX58,AMOTL2,ILDR1,FRMD4A,CRB3,BVES,PARD3B,RAPGEF2,TGFBR1,F11R,MPP5,MICALL2,EPCAM,CCND1,VASP,TJP3,CTNNB1,TBCD,RAP2C,PRKCI,DLG1,CLDN4,POF1B,EPB41L4B,DLG3,FZD5,SHROOM2,OCLN |
| 2.386e-03 | -6.04 | NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS | 663 | 123 | 17758 | 2588 |
CASP3,SIGIRR,ACVR1,TCF25,NF2,S100A11,CNOT8,SUDS3,XIAP,TP53,CUL1,COL18A1,FTH1,BCL2L1,TP53I11,BARD1,IER3,CDKN2C,BTG3,FABP6,FOSB,DLG1,CAPG,BCL6,CDKN1B,IRF2,TAX1BP3,TWIST1,TNFRSF18,CDKN2D,APOBEC3G,SIRT1,CDKN2AIP,BAG4,SOD1,ING1,TNIP1,DRAP1,SERTAD3,CDA,BNIP3L,HTATIP2,ARHGDIB,GLO1,RAD17,PRKRA,SESN1,CDK1,ARHGAP35,SOCS3,MID1IP1,KLF12,PPP2R4,HDAC1,TLE1,NRG1,IRF7,KLF11,GLA,ARF6,HSPB1,CBX4,MAPK12,GLIS3,HSP90B1,RUNX2,ARAP3,NFKBIE,CDKN1C,IGFBP6,SERPINB9,NKRF,NOTCH2,GSTP1,ETS1,RND1,HDAC9,BMP2,RB1,CARD8,IGF1R,TIMP1,PTEN,PAIP2B,BMP7,BAX,ATP8B1,WWP1,PIM1,HEXIM2,TMX1,OSGIN1,SOCS5,MDFI,QSOX1,TGIF1,ELK3,GCLC,FURIN,EMP3,RUNX3,EIF2AK1,NPHP3,RHOB,RASA1,BCL10,FAS,CDK5RAP1,BTG1,TSC1,SERTAD2,SCG2,SEMA4D,ACVRL1,DHRS2,CGREF1,ARAP1,E2F1,IFI6,TOB1,HIPK3,CTBP1,CD33 |
| 2.393e-03 | -6.04 | PEART_HDAC_PROLIFERATION_CLUSTER_UP | MSigDB lists | PEART_HDAC_PROLIFERATION_CLUSTER_UP | 57 | 17 | 17758 | 2588 |
QSOX1,ING1,KIF2C,ANLN,CCNF,SESN1,CDC25C,TNFSF9,MXD1,ARHGAP35,BTG1,STIM1,NEK2,KPNA2,TOB1,CKS2,DUSP1 |
| 2.394e-03 | -6.03 | homeostatic process | biological process | GO:0042592 | 1343 | 237 | 16441 | 2455 |
EMX1,CASP3,GAA,TXN,TRIM24,ADD1,LGR4,IBTK,EPAS1,GRIK2,HEXB,XIAP,TAP1,GATA3,CACNB4,BARD1,SLC8B1,SLC9A7,SESN3,PCNA,PQLC2,TGFBR3,MUC4,CTNNB1,CTGF,P4HB,SIVA1,IL31RA,SLC46A1,ATP13A3,STEAP2,PIK3CA,ABCA2,AKR1B1,CLDN4,TRPC1,CRY2,RAB20,PIK3CD,ACOX2,ZBTB18,SLC39A10,SOD1,CD55,NFE2L1,ERP44,PRKAR2B,PIF1,LDB2,PRIM1,EDNRA,SFXN1,ENPP1,GPRC5B,ATP7B,NOD2,ADIPOR1,HSPB1,F2RL1,SLC31A2,PRKAA2,KLF2,USH1C,DHPS,CALB2,SOX9,MTL5,PRKAA1,ABCG2,SLC25A27,ATP6V1E2,TXNDC9,QSOX2,MECOM,CALR,RAC2,RB1,CA2,GATA2,KCNN4,NPTN,ACAD8,MYLIP,SLC12A2,QSOX1,SLC37A1,MFI2,ANO6,ERO1A,GYLTL1B,PYGL,EIF2AK1,NPC2,PDK3,NPHP3,TP53INP2,NUBP1,SFXN5,STEAP1,FAS,GNAS,FECH,IL1R1,INSR,SLC4A4,HTT,CSF1,ITPR1,SLC4A3,DGAT2,ATP1B3,CCNB2,JAK3,DRD1,EGLN1,EHD1,DMPK,MTM1,CCDC109B,PAX6,SLC2A4,THRA,ATP2C2,TMX4,PDIA5,SOD2,WDTC1,P2RX7,PKP2,FTH1,PRKACA,FLT3,BCAP31,NOV,ATP6V0B,APLP2,SCNN1A,SP100,PLCG2,BCL6,SMO,CNNM4,CDH3,GOT1,STEAP3,IFIT1,TMEM64,F2R,PDIA6,MYT1,CHP1,MYO5B,SIRT1,SOAT1,CLCN3,AKT1,DMTN,ACO1,TEP1,SLC11A2,ATP1B1,RAB38,ITPR3,CD40,TMTC2,ATP13A2,IRS2,DNAJC10,IDE,ATP1A1,ACAD10,AXL,SLC9A6,WFS1,PEX2,INPP4B,STAT1,PTBP3,CHMP4B,AIFM3,ABCA1,PRKAR1A,DYRK3,HSP90B1,POC1B,PDIA3,PKN1,GSTP1,ICAM1,XPR1,SLC9A2,NEO1,PDIA4,ADORA1,SGK3,BAX,SGK1,TMBIM6,ERCC2,RAG1,TTPA,TMX1,ATP2B1,P2RX4,LCA5,GCLC,PIK3R1,RC3H2,EIF5A2,GRIN1,TTC7A,POLD3,BBS2,TXNDC11,PRDX4,CRTC2,LDLRAP1,SWAP70,PROM1,ACADSB,RAB11FIP2,NR1D2,PRCP,NR4A3,PPP2R3C,PKD2,GPER1,LRRK1,MCUR1,ACADM,ATP6V1C1,NDFIP1,SLC25A38,USF2,CYBRD1,FOXA1,ABCG1 |
| 2.395e-03 | -6.03 | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | 165 | 38 | 17758 | 2588 |
GCLM,TXN,DYRK3,GNPDA1,OSGIN2,IL18,CD274,SNX9,DUSP5,SCML1,IER3,SPP1,E2F7,UBE2J1,SELK,EGLN3,SPRY2,ATP2B1,CKS2,DUSP1,P2RX4,PLAUR,RAPGEF2,MGAM,PIM3,SAV1,CDK1,RHEB,PTGS2,SLCO4A1,ETS2,CSF1,MFSD2A,NFKBIZ,PLD1,GLA,GEM,ZC3HC1 |
| 2.395e-03 | -6.03 | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | MSigDB lists | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | 165 | 38 | 17758 | 2588 |
IER5L,CTHRC1,NUAK1,FRMD6,EPHA4,ARL4C,SOD2,SLC1A3,HES2,DSE,CDK14,SPP1,CALD1,BCL6,TRPC1,TWIST1,MOXD1,SNX10,TIAM1,CPE,IL1RAP,CCDC88A,CYP1B1,ADAMTS2,PDGFC,SALL4,PGBD1,ANTXR1,COL12A1,EDNRA,TIMP3,PLOD2,ISM1,AXL,WWTR1,RAB31,LTBP2,ST3GAL1 |
| 2.396e-03 | -6.03 | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | 117 | 29 | 17758 | 2588 |
PVRL4,CPEB4,DENND1B,KDELR3,IL13RA1,SYTL4,HEATR5A,CCNF,NPDC1,CDC25C,TMPRSS4,GLT8D2,SRPX2,ZNF469,ARF4,FANCI,SYTL2,C16orf59,AP1M2,RAB11FIP1,SLC44A2,VAT1,GLB1,TACSTD2,KNTC1,MARCH2,NAGA,S100A6,GPR161 |
| 2.402e-03 | -6.03 | ADHERENS_JUNCTION | MSigDB lists | ADHERENS_JUNCTION | 22 | 9 | 17758 | 2588 |
ZYX,SORBS1,CDH1,SHROOM3,SORBS3,AIF1L,SHROOM2,BCAR1,RND1 |
| 2.402e-03 | -6.03 | GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION | MSigDB lists | GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION | 22 | 9 | 17758 | 2588 |
TXN,SLC25A4,WDTC1,SOD2,PRKG1,BAX,BCL2L1,PRKACA,GPX4 |
| 2.405e-03 | -6.03 | CHIN_BREAST_CANCER_COPY_NUMBER_UP | MSigDB lists | CHIN_BREAST_CANCER_COPY_NUMBER_UP | 26 | 10 | 17758 | 2588 |
CCND1,TOP2A,CD109,NCOA3,PTGS2,THRA,MYBL2,ERBB2,AURKA,CTTN |
| 2.405e-03 | -6.03 | GCM_DEAF1 | MSigDB lists | GCM_DEAF1 | 26 | 10 | 17758 | 2588 |
NAPG,TMEM184B,GPR107,RAPGEF2,TMEM30A,FOXJ2,DDHD2,FBXO9,KIAA1109,DNAJB14 |
| 2.407e-03 | -6.03 | Netrin-1 signaling | REACTOME pathways | R-HSA-373752 | 42 | 14 | 8202 | 1235 |
PLCG1,FYN,RGMB,EZR,TRPC1,PITPNA,NTN4,PRKCQ,UNC5B,NTN1,TRPC3,ABLIM2,NEO1,RGMA |
| 2.410e-03 | -6.03 | MARTINEZ_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_TP53_TARGETS_DN | 560 | 106 | 17758 | 2588 |
TRIM2,KLK10,PAX6,FAM92A1,EPAS1,ST14,CRYM,THRA,DNAJC3,RHBDL3,FHDC1,TP53,IRX4,PKP2,COL18A1,CCNL1,DDR1,SLC9A3R2,CCND1,APLP2,GRHL1,SIVA1,FRYL,ZFP36,ALDH1A3,SLC44A1,SMO,ABCA2,CDH3,RPN2,ECE1,MYH14,TECR,ETHE1,SCARA3,EGLN3,PTPRE,SULT2B1,TUBA4A,PLK1,CLCN3,MBP,COL6A2,CENPA,CXXC5,CELSR2,USP18,SNTB2,PANK1,KIF1C,ITPR3,FZD7,OVOL1,AGFG2,TMOD2,UNC5B,SLC25A30,TC2N,CD99,LASP1,COL9A3,PCOLCE,HJURP,CTSB,ESRP1,DAP,SOX9,RAB6A,GSTP1,EFNB1,LGALS3BP,FZD6,NEO1,TMCC3,CALR,CTNNBIP1,DOPEY2,TIMP1,CALD1,ATP5H,IGFBP2,FAM134C,EPHX1,IGDCC4,NFE2L3,SHMT1,CTNNAL1,GCLC,ELOVL3,FHL2,MYBL2,NFIB,EGFR,FRMD4B,PTPRF,TIMP3,CTNS,FA2H,PVRL2,PLOD2,CLIP4,LTBP2,MAP3K5,RARG,SNX30,XDH |
| 2.422e-03 | -6.02 | single-organism transport | biological process | GO:0044765 | 3092 | 513 | 16441 | 2455 |
DOC2A,ACACB,ADD1,IBTK,GRIK2,SLC25A13,MCOLN3,CACNA2D2,TRAPPC8,TGOLN2,LGI3,BAIAP3,SYTL4,SNX9,SLC35E4,TP73,CALM2,NAPG,PQLC2,AP1M2,SLC46A1,ATP13A3,DNM2,TINAGL1,PIK3CD,TMEM37,TUBA4A,VPS11,UXT,PRKAR2B,ICMT,RNF19B,SLC44A3,ENPP1,PLCG1,LIMK1,ATP7B,TRAF3IP1,NOD2,RNASEL,ANXA11,SCN5A,NFKBIE,SEC61G,SLC36A4,COX6C,FAM21C,MERTK,TTYH3,LMNA,ATG4A,ATP5H,RIMS3,FBXO7,PCYOX1,CADPS2,PANX2,CNGA1,NUP85,PPP6R1,NAGPA,UFD1L,SLC37A1,ERO1A,CALCRL,PLS1,SRSF5,PCTP,SFXN5,RHOB,CYB5A,CACHD1,SCARB2,SLC4A4,TIMM8A,HTT,ITPR1,NDE1,ARPC2,TRPC3,NUP58,XDH,MTM1,CCDC109B,APOO,PRKACA,CCND1,SCNN1A,ACSL4,ARL4D,RAB27B,SCN3A,SNX8,SEC61B,FZD4,VPS4B,RAB38,PEX5,STX10,CORO1C,SLC9A6,AXL,SLC25A30,TAOK2,HSP90B1,HABP4,FLOT1,BTN3A1,PDIA3,CTSZ,ANO9,KCNC4,IFT27,SLC25A43,PDIA4,SLC25A45,ANK1,ADD3,SLC27A6,CTSC,FAM160A2,KCNK5,BAX,KLC3,WWP1,TPCN1,S100A6,HCN3,LCA5,PIK3R1,MRS2,GRIN1,RAB3IP,NEURL1B,FAM109A,RGPD5,LDLRAP1,RPL12,RAB11FIP2,SYT7,SLC35B3,NR4A3,ARFGAP3,SSNA1,ITGAV,NUP37,CD81,USF2,SRSF9,CYBRD1,ARFGEF1,F11R,ITPR2,HDAC6,PDGFB,NUP210,CTNNB1,ARL1,LMAN2L,SLC44A1,ABCA2,ANO4,TRAM1,S100A13,KCNIP3,CELSR2,EZR,ARFRP1,ESYT1,CLCN2,VCP,OPTN,TRIM9,TBC1D17,KCNMB4,WIPI1,RAB11FIP1,KPNA2,PIEZO1,TC2N,PRKAA2,FXYD3,SLC22A31,RACGAP1,RAB6A,NCKAP1,ANO1,PGAP1,SSX2IP,TIMP1,GATA2,ICAM5,KIF13B,SLC30A6,EXOC8,SELK,ABCC1,STRADB,SCRIB,EIF2AK1,ZDHHC3,MFSD2A,SLC2A6,ZDHHC7,LTBP2,ATP1B3,PLD1,NIPA1,KCNAB3,UPF3B,TP53,P2RX7,SLC7A2,EMP2,BCAP31,SDF4,SYTL2,TTC21B,PDGFA,ATP6V0B,SRPX,PLCG2,BCL6,ZDHHC23,SCN2A,LMAN1,GM2A,PPIF,CLCN3,AKT1,ACO1,DAG1,ATP13A2,TAPBP,ATP1A1,MAOA,CHMP4B,SYT13,RPL22,COPG1,MFSD14B,TRAPPC10,CD63,GABRG2,AIP,VPS26A,SLC9A2,ZDHHC21,M6PR,CDK16,SLC35B4,SGK1,ABCD1,CPLX1,SYK,SLC45A3,CAMK2G,ATP2B1,P2RX4,HES1,FBLN5,PPARA,PRICKLE1,COL7A1,AKAP3,BBS2,SCRN2,SERPINA1,SCG2,TMC5,PKD2,SPCS3,NDFIP1,ARHGEF9,LAMP1,SLC35D2,ATP8A1,TSC22D3,KLC2,TAP1,GATA3,SLC20A1,RIC1,NCS1,SLC9A7,PICK1,CTGF,ELMO2,STIM1,OSBPL3,PIK3CA,SERINC2,KCNS3,STEAP2,SNX16,PACSIN1,TFG,XKR8,LAMP2,ORAI2,BNIP3L,SLC35C1,KIF13A,SLC17A5,MCFD2,SLC25A5,SPNS3,SFXN1,SLC25A4,AREG,GNPTAB,SARAF,SLC31A2,F2RL1,SLC25A27,NDUFA4,SLC1A3,APBA1,CALR,DOPEY2,SNX18,NECAB3,SLC16A6,RPL39,SORL1,CACNA1D,PIKFYVE,SYTL3,RIMS2,TMED2,TRAK2,KCNJ12,GCC2,PMPCB,MFI2,ANO6,CALM1,ATP8B3,NPC2,CYFIP2,STX3,GABRD,AP1AR,SLCO4A1,PRKAG2,ZDHHC20,WDR19,SLC4A3,HOOK1,NRBP1,EHD1,PKD1L2,MFSD3,PLA2G4A,KIF3C,SLC2A4,RALBP1,ATP2C2,FTH1,BCL2L1,DDR1,ZFYVE9,CNNM4,TNPO2,CDKN1B,OSBPL7,ATG4D,TBC1D10B,MYO5B,SLC5A11,SEC23A,COG2,DMTN,KIF1C,COX11,SLC11A2,ATP1B1,ITPR3,ATP10D,OSBPL2,FYN,DDOST,RAB29,SLC27A1,PRKAR1A,DENND5B,SLC16A14,SLC41A1,ATP9A,ARL4C,PLD2,CYB561,COX7A2,SLC25A36,PPP1R10,CD9,SGK3,SLC44A2,ATP8B1,TTPA,SLC16A5,NCOA2,CASK,ZC3H11A,FURIN,VAMP3,YES1,CPTP,GPLD1,CTNS,FGFR2,SLC25A40,ABCB1,GRIN2D,ARSB,ESYT2,EXPH5,FAF2,CRYM,CPT2,UBE2Q1,SLC8B1,ERP29,CACNB4,TMC1,ABCD4,ZFYVE16,RAB15,DPYSL2,TRPC1,RAB20,RP2,SLC39A10,RASGRP1,SOD1,ADRBK2,TCN2,EDNRA,KCNK1,PCSK5,GRN,LASP1,PEX6,ABCG2,CALM3,ATP6V1E2,CA2,KCNN4,PRKCI,FXYD5,SRP54,SLC12A2,GAD1,BTN3A2,STEAP1,MFSD7,GNAS,TSC1,SLC6A6,TMEM30A,NFKBIA,RAB31,SH3BP4,PITPNA,JAK3,SHROOM2,APOL2,TOB1,DRD1,SLC25A24,SORBS1,SLC2A8,ABCG4,MICALL2,SVBP,SLC25A48,KIF14,ZDHHC12,FABP6,RPN2,STEAP3,F2R,CHP1,SOAT1,OSTM1,SLC39A8,AP5M1,ALDH5A1,PEX2,SPTBN5,ABCA1,ANXA3,SORT1,SH3D19,ITGA2B,HMGXB4,TMEM63A,KIF5B,ADRBK1,ADORA1,LLGL2,ZDHHC13,RPGR,SLC35A1,MYO5A,RAB3B,MAP1B,ARRB1,SLC18B1,MCUR1,ATP6V1C1,SNPH,ABCG1 |
| 2.425e-03 | -6.02 | GSE17580_TREG_VS_TEFF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_UP | 187 | 42 | 17758 | 2588 |
FAM89A,TTC39B,UPF3B,CDKN1C,GCAT,CNTROB,GALM,PHLPP1,DHRS3,SDF4,SYTL2,EPCAM,RCN1,GNB5,CD70,PIM1,F2R,GFI1,SMC4,FAH,ABCC1,EPHX1,PQLC3,CEP89,SH3BGRL,CORO2A,CBX6,PCTP,SESN1,VCP,GPLD1,GABARAPL1,SOCS3,TWSG1,SYT7,H1F0,MATN2,MAOA,SH3BGRL2,CPPED1,RRAGD,XDH |
| 2.425e-03 | -6.02 | GSE30083_SP1_VS_SP2_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP2_THYMOCYTE_UP | 187 | 42 | 17758 | 2588 |
GAA,SLC2A4,ENO2,LMCD1,FLOT1,TDRKH,BAIAP3,SEPT4,C11orf95,ICAM1,RALB,CASC4,TSPAN6,SGK1,ALDH7A1,ARMCX6,EGLN3,CNPY3,HCN3,HES1,PODXL2,ALDH2,CITED4,SERTAD4,CORO2A,PLEKHO1,FBXO8,PRKAR2B,BCL7B,FOS,RNPEP,ADRBK2,LRRC42,SLCO4A1,NUCB1,ALDH3B1,PAFAH1B3,KCNK1,SH3BP4,GLB1,LRRK1,DMWD |
| 2.425e-03 | -6.02 | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN | 187 | 42 | 17758 | 2588 |
KIF3C,SLC35D2,CDK17,DNAJC3,SRPX2,DUSP5,FLII,SRPX,CDH1,CYR61,SH3BP1,CD22,OSBPL3,SRR,AKR1B1,ACTA2,TWIST1,ZNF230,NFKB2,DLX4,DUSP1,TNIP1,STAT4,RAPGEF2,PLAUR,CASP9,LITAF,HTATIP2,OPTN,MMP15,MDK,PEX5,JAK1,TIMM8A,NFKBIA,INPP4B,NRG1,PDXK,DRP2,ITPKA,PTGES,EHD1 |
| 2.425e-03 | -6.02 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 187 | 42 | 17758 | 2588 |
BIN1,RMND5A,GAA,IQGAP1,TSC22D3,BLVRB,HEXB,PDIA3,TEX2,TGOLN2,FAM198B,CDIPT,FBLN1,APPBP2,SGPL1,IMPAD1,DDHD2,PCYOX1,H2AFY,TAGLN2,SLC35A1,PHKG2,S100A6,HP1BP3,RHOA,MPP1,DSTN,EIF2AK1,BLVRA,FOS,ZMPSTE24,LRRC42,TRAM2,ATP1A1,DDOST,RCBTB2,AMMECR1,PLA2G15,IARS2,PKD2,CHPT1,KLF7 |
| 2.428e-03 | -6.02 | actin-based cell projection | cellular component | GO:0098858 | 164 | 38 | 17570 | 2579 |
TPRN,MTM1,FARP1,INPPL1,USH1C,NF2,EPS8,EPHA4,ARL4C,UBE2Q1,ERBB2,TMC1,PLS3,PDGFA,VASP,ITGA3,CA2,CTNNB1,AKR1B1,ACTA2,ATP8B1,ESPN,MYO5A,DOCK4,MPP1,SYNE2,UTRN,SPATA13,EZR,ANTXR1,DAG1,LCP1,PROM1,CTSV,ITGAV,ARF6,FOXA1,PROM2 |
| 2.450e-03 | -6.01 | regulation of metal ion transport | biological process | GO:0010959 | 327 | 68 | 16441 | 2455 |
CACNA2D2,PKP2,P2RX7,PRKACA,CACNB4,PDGFB,CALM2,NKAIN3,CTNNB1,STIM1,CABP1,PLCG2,DLG1,DNM2,TRPC1,PDE4D,F2R,HSPA2,CHP1,KCNIP3,AKT1,UTRN,NKAIN1,ATP1B1,PLCG1,PTGS2,ATP1A1,WFS1,MYLK,CAB39,SARAF,SLC31A2,PRSS8,SCN5A,LGALS3,SERPINE2,CD63,UBASH3B,FXYD3,CALM3,ICAM1,WWP2,SNTA1,KIF5B,GNB5,ADORA1,BAX,SGK3,SGK1,FXYD5,TSPAN13,CACNA1D,MYO5A,CAMK2G,P2RX4,CASK,RHOA,CALM1,HTT,PKD2,STK39,FHL1,ATP1B3,GPER1,TRPC3,JAK3,DMPK,DRD1 |
| 2.451e-03 | -6.01 | human chr12q22 | chromosome location | human chr12q22 | 29 | 9 | 26250 | 2805 |
BTG1,FGD6,NTN4,VEZT,NDUFA12,LTA4H,NR2C1,METAP2,TMCC3 |
| 2.461e-03 | -6.01 | phosphoric ester hydrolase activity | molecular function | GO:0042578 | 357 | 73 | 16491 | 2452 |
MTM1,DLGAP5,SSH1,PPM1J,INPP5D,CTDSPL,PHOSPHO1,LPIN3,EPM2A,INPP5E,IMPAD1,PLCG2,PALD1,PAPL,DLG1,DUSP10,PDE4D,PPP1CA,MINPP1,PTPRE,CTDSP2,TDP1,SSH3,PTPN18,PTPRU,PFKFB2,PTPN9,PXYLP1,DUSP4,CDC25C,EDNRA,SGPP1,PLCH1,ENPP1,PLCG1,ATP1A1,PTPRJ,GDE1,INPP4B,PPP1CB,PPP2R5D,CPPED1,CTDSP1,TMEM55B,UBASH3B,PDIA3,PLD2,PHLPP1,PLPPR4,SBF1,DUSP5,PGAP1,ADORA1,ALPP,PTEN,OCRL,PPP4R1,PIKFYVE,PLCB2,CAMK2G,DUSP1,DUSP23,PTPRH,PDE5A,PDE11A,GPLD1,PTPRF,NUDT16,NT5C2,PLPP3,PHLPP2,PPM1H,PLD1 |
| 2.464e-03 | -6.01 | ROZANOV_MMP14_TARGETS_UP | MSigDB lists | ROZANOV_MMP14_TARGETS_UP | 260 | 55 | 17758 | 2588 |
PCOLCE,ENO2,FRMD6,PYROXD2,BACE1,COL18A1,PDGFRL,PLA2G16,S100A2,SRPX2,LGALS3BP,SIRPA,SGPL1,B3GALNT1,ADD3,SCNN1A,CTGF,CALD1,COL6A1,DAPK1,H2AFY,RAB20,IGFBP2,PIK3CD,LGMN,NCAM1,SNX10,CPE,SULF2,MX1,NFE2L3,COL6A2,CXXC5,SPATA18,NR3C1,DSTN,SEPT6,TMEM98,PNKD,CD83,MDK,FUCA1,IL1R1,HLA-B,ENPP1,TIMP3,PLOD2,PLK2,STK38,MYLK,LRIG1,MATN2,UACA,PLXND1,SHROOM2 |
| 2.470e-03 | -6.00 | right_middle_lobe | COSMIC cancer mutations | right_middle_lobe | 8 | 5 | 17775 | 2585 |
ERBB2,CTNNB1,EGFR,PIK3CA,TP53 |
| 2.470e-03 | -6.00 | mixed_cell_carcinoma | COSMIC cancer mutations | mixed_cell_carcinoma | 8 | 5 | 17775 | 2585 |
CTNNB1,FGFR2,PTEN,PIK3CA,TP53 |
| 2.470e-03 | -6.00 | endometrium-carcinoma-mixed_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mixed_cell_carcinoma | 8 | 5 | 17775 | 2585 |
CTNNB1,FGFR2,PTEN,PIK3CA,TP53 |
| 2.470e-03 | -6.00 | large_intestine-serrated_polyp-serrated_adenoma | COSMIC cancer mutations | large_intestine-serrated_polyp-serrated_adenoma | 8 | 5 | 17775 | 2585 |
GNAS,CTNNB1,EGFR,PIK3CA,TP53 |
| 2.474e-03 | -6.00 | angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | angioimmunoblastic_T_cell_lymphoma | 272 | 57 | 17775 | 2585 |
CPEB4,SHPRH,SUZ12,TP53,GATA3,SAMD9,ITPR2,NOTCH2,PHLPP1,FLT3,ETS1,TNFSF9,SLC9A2,CCND1,BTG3,RB1,MUC16,CTNNB1,IRAK1,TACC2,PTEN,GATA2,FABP6,PLCG2,BCL6,SGK1,BRD7,CD70,NOTCH3,PIM1,NFKB2,SYK,HP1BP3,SMARCA2,PDGFC,RHOA,CELSR2,ASXL1,TACC1,NR3C1,BCL9,PIK3R1,UBE2A,KIF20B,IDH1,FAS,BCL10,GNAS,BTG1,PLCG1,JAK1,STAT6,TMEM30A,NFKBIA,JAK3,CBX5,RAD21 |
| 2.476e-03 | -6.00 | peripheral nervous system development | biological process | GO:0007422 | 70 | 20 | 16441 | 2455 |
SOD1,UGT8,AKT1,NDRG1,ERBB2,RUNX3,MPP5,EGR3,ILK,DAG1,ADGRB2,ARTN,FA2H,NAB2,TFAP2A,SERPINI1,NRG1,ERBB3,SOX8,ALDH3A2 |
| 2.476e-03 | -6.00 | renal tubule morphogenesis | biological process | GO:0061333 | 70 | 20 | 16441 | 2455 |
HES1,LGR4,FMN1,SOX9,DCHS1,GATA3,ILK,IRX3,CTNNBIP1,BMP2,CTNNB1,FAT4,NPNT,GPC3,DLG1,PKD2,TACSTD2,SOX8,OSR1,ADAMTS16 |
| 2.484e-03 | -6.00 | intracellular transport | biological process | GO:0046907 | 1375 | 242 | 16441 | 2455 |
LAMP1,EXPH5,UNC93B1,ACACB,FAF2,IBTK,GRIK2,CPT2,SLC25A13,KLC2,TAP1,TRAPPC8,TGOLN2,SYTL4,HDAC6,SNX9,SLC8B1,ERP29,RIC1,PICK1,ZFYVE16,NAPG,RAB15,AP1M2,ARL1,LMAN2L,STEAP2,DNM2,SNX16,RAB20,RP2,PIK3CD,TINAGL1,CTTN,TFG,TRAM1,MYRIP,S100A13,RASGRP1,VPS11,SOD1,UXT,BNIP3L,ARFRP1,KIF13A,ICMT,MCFD2,RAB2B,VCP,OPTN,TBC1D17,WIPI1,AREG,GNPTAB,ATP7B,TRAF3IP1,KPNA2,PRKAA2,GGA1,PEX6,SEC61G,RAB23,RAB6A,SLC1A3,APBA1,FAM21C,PGAP1,LMNA,SSX2IP,ATG4A,CALR,DOPEY2,SNX18,GATA2,ATP5H,RPL39,KIF13B,FBXO7,RANBP1,PRKCI,SORL1,SRP54,PIKFYVE,SYTL3,NUP85,PPP6R1,TMED2,RIMS2,KDELR1,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,ERO1A,STRADB,NPC2,SRSF5,ZDHHC3,RHOB,NMT2,STX3,GNAS,TSC1,AP1AR,SCARB2,PRKAG2,TIMM8A,HTT,WDR19,ZDHHC20,NFKBIA,ITPR1,RAB31,ZDHHC7,CTSA,LTBP2,NDE1,HOOK1,JAK3,NRBP1,TOB1,NUP58,DRD1,EHD1,KIF3C,MTM1,SLC25A24,CCDC109B,UPF3B,TP53,P2RX7,FTH1,BCL2L1,MICALL2,EMP2,BCAP31,ZFYVE9,APPBP2,SYTL2,TTC21B,ZDHHC12,KIF14,PLCG2,BCL6,ZDHHC23,TNPO2,RPN2,IFIT1,LMAN1,RAB27B,F2R,UPF3A,TBC1D10B,ATG4D,CHP1,PPIF,SNX8,SEC23A,SEC61B,AKT1,COG2,VPS4B,HTATIP2,KIF1C,AP5M1,ATP1B1,RAB38,ITPR3,ATP10D,DAG1,TAPBP,PEX5,STX10,DDOST,PEX2,CHMP4B,SPTBN5,RAB29,RGS14,RPL22,SLC25A30,ABCA1,COPG1,SORT1,HSP90B1,TAOK2,TRAPPC10,CD63,ATP9A,SH3D19,ARL4C,PDIA3,CTSZ,IFT27,AIP,VPS26A,HMGXB4,ZDHHC21,M6PR,KIF5B,SNX13,ANK1,ADORA1,MLPH,CTSC,PPP1R10,FAM160A2,KLC3,BAX,ABCD1,SYK,RPGR,MYO5A,HES1,LCA5,RAB3B,ZC3H11A,PIK3R1,MRS2,VAMP3,PRICKLE1,COL7A1,RAB3IP,FAM109A,BBS2,MAP1B,RGPD5,LDLRAP1,RPL12,SERPINA1,NR4A3,ARFGAP3,ARRB1,SSNA1,PKD2,SPCS3,MCUR1,ARSB,NDFIP1,SRSF9,ABCG1 |
| 2.486e-03 | -6.00 | human chr1q32 | chromosome location | human chr1q32 | 40 | 11 | 26250 | 2805 |
MAPKAPK2,CD46,ELK4,CD55,LPGAT1,CR2,RAB29,PIK3C2B,RNPEP,TRAF5,SOX13 |
| 2.486e-03 | -6.00 | negative regulation of cellular component movement | biological process | GO:0051271 | 232 | 51 | 16441 | 2455 |
SEMA6B,TCAF1,ARAP3,NF2,ADGRG1,PKP2,GATA3,VASH1,FBLN1,CORO1B,NOV,SVBP,PDCD10,TGFBR3,TIMP1,ADORA1,SP100,PTEN,ADAM15,CDKN1B,DAB2IP,TACSTD2,SEMA3G,CITED2,WNT3A,CYP1B1,SEMA3B,ACVR1C,PTPRU,PTGER4,RGCC,ARHGDIB,EPHA1,ILK,DAG1,RHOB,ABR,DPYSL3,AP1AR,PTPRJ,SEMA4D,ACVRL1,CORO1C,SPINT2,RAP2C,EGFL7,NRG1,ARHGAP4,SEMA3A,MIIP,DRD1 |
| 2.492e-03 | -5.99 | Trim69 (tripartite motif-containing 69) | protein interactions | 70928 | 36 | 13 | 16036 | 2547 |
GNAS,FYN,MPRIP,PPP1R12A,ALPP,TRIM69,LYPD3,ABCG2,FLOT1,YES1,PKM,FLOT2,GNB2 |
| 2.494e-03 | -5.99 | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_2HR | MSigDB lists | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_2HR | 8 | 5 | 17758 | 2588 |
ZNF462,CENPA,BORA,SEMA3B,E2F1 |
| 2.494e-03 | -5.99 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_DN | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_DN | 8 | 5 | 17758 | 2588 |
CASP7,BCL2L1,EGLN3,MAPK8IP1,DAPK1 |
| 2.504e-03 | -5.99 | nerve_sheath | COSMIC cancer mutations | nerve_sheath | 48 | 15 | 17775 | 2585 |
GNAS,RB1,SS18,NF2,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR |
| 2.511e-03 | -5.99 | GBP2 (guanylate binding protein 2, interferon-inducible) | protein interactions | 2634 | 32 | 12 | 16036 | 2547 |
GNS,CASP7,PAFAH1B3,RPS6KA1,SERPINB9,SAT1,BNIP3L,NANS,GLA,TFG,CAPN1,SEPHS1 |
| 2.511e-03 | -5.99 | Ndc80 (NDC80 homolog, kinetochore complex component (S. cerevisiae)) | protein interactions | 67052 | 32 | 12 | 16036 | 2547 |
HMMR,RCN1,ZWINT,SPC25,ASPM,RRBP1,NDC80,NUF2,BUB1,IQGAP3,PHKA2,ODF2L |
| 2.512e-03 | -5.99 | Liver enzyme levels (alkaline phosphatase)(PMID:22001757) | GWAS genes | Liver enzyme levels (alkaline phosphatase)(PMID:22001757) | 8 | 5 | 2389 | 350 |
FADS2,FUT2,ABHD12,GPLD1,NBPF3 |
| 2.513e-03 | -5.99 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | 160 | 37 | 17758 | 2588 |
MYL9,SORT1,ACVR1,HSPG2,ZCCHC24,APBA1,FAM101B,SRPX2,ANO1,C1orf116,CAPN2,CALD1,ACTA2,RGS5,KANK2,TLN2,MAPK7,MDFI,ATL1,PRICKLE1,PDE5A,SAV1,EDNRA,ENDOD1,DDAH1,CACHD1,ENPP1,TIMP3,MPRIP,AGPAT2,MYLK,SLC4A3,UACA,FHL1,CEP41,STARD13,CD81 |
| 2.517e-03 | -5.98 | KEGG_COLORECTAL_CANCER | MSigDB lists | KEGG_COLORECTAL_CANCER | 62 | 18 | 17758 | 2588 |
CASP3,RHOA,AKT1,CASP9,PIK3R1,TP53,TCF7,TGFBR1,APC2,FOS,CCND1,RAC2,CTNNB1,BAX,PIK3CA,MSH2,PIK3CD,MSH6 |
| 2.517e-03 | -5.98 | response to alcohol | biological process | GO:0097305 | 316 | 66 | 16441 | 2455 |
CASP3,SLC2A4,NQO1,IL15,GATA3,ITPR2,BCL2L1,PDGFB,SDF4,CALM2,CCND1,CCNA2,CDH1,CTNNB1,CTGF,FOSB,SMO,CDKN1B,ARNT2,OSBPL7,CDKN2D,SOD1,CASP9,SOCS3,PTGS2,FYN,MAP2,AREG,GRN,KLF2,NKX3-1,CTSB,PRKAA1,EPS8,CALM3,TGFBR1,ETS1,ICAM1,CALR,TFAP4,SPP1,OXCT1,PTEN,BMP7,CST3,BAX,IGFBP2,KLF9,PIM1,DUSP1,RHOA,CALM1,GRIN1,GGH,ELK1,FOS,EGFR,GPLD1,MMP15,FECH,NCOA3,AURKA,HOXB13,GPER1,FOXA1,DRD1 |
| 2.518e-03 | -5.98 | protein kinase complex | cellular component | GO:1902911 | 91 | 24 | 17570 | 2579 |
PRKAA2,CCNC,SORBS1,ACVR1,ACVR1C,NUAK1,PRKAA1,TGFBR1,PRKAR2B,CCNL1,PRKACA,CDK14,CCND1,PRKAG2,INSR,PRDX3,GTF2F2,CAB39,ERCC2,PHKA2,MAP3K5,MAP3K7,PHKG2,PRKAR1A |
| 2.520e-03 | -5.98 | PTB | interpro domains | IPR013625 | 8 | 5 | 18293 | 2672 |
TNS4,TNS1,TNS3,EPS8,EPS8L2 |
| 2.520e-03 | -5.98 | PTPRJ (protein tyrosine phosphatase, receptor type, J) | protein interactions | 5795 | 17 | 8 | 16036 | 2547 |
PLCG1,PTPRJ,LGALS3,CTNNB1,LGALS8,CTNND1,FBXO6,EGFR |
| 2.520e-03 | -5.98 | EIF2AK3 (eukaryotic translation initiation factor 2-alpha kinase 3) | protein interactions | 9451 | 17 | 8 | 16036 | 2547 |
HSP90B1,HLA-E,SUZ12,DNAJC3,RHBDL3,BCL6,HLA-C,GLT8D2 |
| 2.520e-03 | -5.98 | KCNJ12 (potassium channel, inwardly rectifying subfamily J, member 12) | protein interactions | 3768 | 17 | 8 | 16036 | 2547 |
SNTA1,CASK,SNTB2,DLG1,SNTB1,DLG3,APBA1,PRKACA |
| 2.524e-03 | -5.98 | mesonephric tubule morphogenesis | biological process | GO:0072171 | 56 | 17 | 16441 | 2455 |
HES1,FMN1,DCHS1,SOX9,GATA3,ILK,CTNNBIP1,BMP2,CTNNB1,FAT4,NPNT,GPC3,DLG1,TACSTD2,PKD2,OSR1,ADAMTS16 |
| 2.526e-03 | -5.98 | ATATGCA,MIR-448 | MSigDB lists | ATATGCA,MIR-448 | 204 | 45 | 17758 | 2588 |
DOC2A,SCN5A,TRAPPC10,ADD1,FAM160B1,GRIK2,EPHA4,UBE2Z,C6orf106,DNAJB11,RNF182,SH3KBP1,KCTD9,APPBP2,RAVER2,SS18,BTG3,KCTD15,CEP97,IGF1R,IMPAD1,DACT1,XYLT2,DAPK1,WWP1,NCOA2,SOCS5,SIRT1,PLEKHA6,PRKAR2B,CASP4,RAB2B,GLCE,USP6,IRS2,SERTAD2,RAB11FIP2,CDK19,AMMECR1,RAP2C,KLF5,CPEB2,AHR,LRRC57,DOCK9 |
| 2.527e-03 | -5.98 | diacylglycerol binding | molecular function | GO:0019992 | 11 | 6 | 16491 | 2452 |
RASGRP3,CDIPT,CHPT1,RAPGEF2,RASGRP1,RASGRP2 |
| 2.530e-03 | -5.98 | HOOI_ST7_TARGETS_DN | MSigDB lists | HOOI_ST7_TARGETS_DN | 107 | 27 | 17758 | 2588 |
TMTC1,ENO2,LRRFIP2,TBC1D8B,NDRG1,DENND1B,MCOLN3,PDK3,PRKRA,TRIB2,VASH1,FAM46C,STK17B,PGAP1,PAK6,CXCL16,KCTD15,DHRS2,ITPR1,CSGALNACT1,ZDHHC13,DCUN1D1,NFKBIZ,CADPS2,SPRY4,APOBEC3G,FOXA1 |
| 2.539e-03 | -5.98 | CLEC7A (Dectin-1) signaling | REACTOME pathways | R-HSA-5607764 | 99 | 26 | 8202 | 1235 |
PSMB4,TAB3,PSME2,CALM1,PSMD7,PSMD10,CALM3,CUL1,PSME1,ITPR2,ITPR3,PSMA4,BCL10,CALM2,PSMD1,PSMD3,NFKBIA,PLCG2,PSMC2,ITPR1,UBE2D2,MAP3K7,NFKB2,PSMC1,SYK,PSMA5 |
| 2.543e-03 | -5.97 | blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | blastic_plasmacytoid_dendritic_cell_neoplasm | 67 | 19 | 17775 | 2585 |
AKT1,ASXL1,RET,TP53,ERBB2,IDH1,FLT3,GNA11,EGFR,GNAS,RB1,CDH1,CTNNB1,PTEN,GATA2,FGFR2,PIK3CA,SMO,JAK3 |
| 2.548e-03 | -5.97 | Cyclin E associated events during G1/S transition | REACTOME pathways | R-HSA-69202 | 65 | 19 | 8202 | 1235 |
CCNE2,PSMB4,PSME2,PSMD7,CUL1,PSMD10,PSME1,PKMYT1,PSMA4,WEE1,RB1,CCNA2,PSMD1,PSMD3,PSMC2,CKS1B,CDKN1B,PSMC1,PSMA5 |
| 2.550e-03 | -5.97 | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDM_UP | 193 | 43 | 17758 | 2588 |
FBLIM1,PINK1,UGP2,ADD1,GNPDA1,MRPS15,CPT2,CDCA3,STRN4,TESK2,FAM198B,MGST2,HDAC6,NUCB2,TMPRSS4,XPR1,FAM111A,WEE1,SLC25A45,ELMO2,TBCD,GYS1,PLEKHF1,HMGCL,ERBB3,MYO5A,CENPA,CDC20,MGAT4B,FBXO9,CTNS,MTFMT,WFS1,PLA2G15,RAB31,NR4A3,PNPLA6,FAM117A,PDXK,PLIN3,CBX4,RPS6KA3,CTDSP1 |
| 2.550e-03 | -5.97 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP | 193 | 43 | 17758 | 2588 |
WASF3,SIGIRR,LGR4,CKAP2,GCAT,ABCG2,GATA3,CALM3,TDRKH,SEPP1,MERTK,C11orf95,STIL,FANCI,IL17RB,CALM2,TOP2A,CEP97,CNTRL,KCNK5,BUB1,TSPAN13,GFI1,RASGRP1,CAMK2G,SMC4,FAM69A,CKS2,PGM1,STAT4,CALM1,PTGER4,ARHGDIB,LRRC1,KIF11,PLEKHB1,KCNMB4,SEMA4D,C1orf21,INPP4B,STK39,CBX5,EHD1 |
| 2.550e-03 | -5.97 | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | 193 | 43 | 17758 | 2588 |
SEMA6B,DYRK3,PAPSS2,IQGAP1,FLOT1,CBLL1,CDIPT,PHLPP1,EXT2,NRP2,LMNA,RAD23A,AKIRIN1,B3GALNT1,CYP1A1,PPP4R1,COL6A1,CD9,OPN3,GPR161,CERS2,CYP1B1,MX1,P2RX4,SYPL1,CDKN2AIP,PDGFC,PLSCR1,KIAA0040,ITCH,EMP3,ERBB2IP,MAP3K6,IL1R1,SWAP70,FAM64A,PVRL2,UEVLD,ANKRD6,SIPA1L1,TDRD7,ATP6V1C1,MELK |
| 2.557e-03 | -5.97 | GNF2_PTPN6 | MSigDB lists | GNF2_PTPN6 | 48 | 15 | 17758 | 2588 |
HLA-B,TAPBP,RAC2,ACAP2,HLA-E,HLA-F,STAT6,FXYD5,SELL,EMP3,ARHGDIB,GRK6,HLA-C,ANXA11,HLA-A |
| 2.558e-03 | -5.97 | GSE17721_POLYIC_VS_CPG_6H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDM_DN | 182 | 41 | 17758 | 2588 |
HJURP,SEC61G,RHBDL3,STRN4,ABCG2,PSMD7,PHLDA1,CKAP5,MAGOHB,CCDC92,CAPN2,NOV,ADRBK1,RALB,XYLT2,ATP13A3,SLAIN2,NFKB2,MYLIP,TMBIM1,TMX1,FAH,ABCC1,CKS2,PPIF,ADAM17,ERLEC1,PTGER4,ARFRP1,CYFIP2,STK17B,LCP1,RHOB,VCP,FOXD2,CRTC2,ETS2,PPP1CB,KLF5,PER3,TLL2 |
| 2.563e-03 | -5.97 | RASA1 (RAS p21 protein activator (GTPase activating protein) 1) | protein interactions | 5921 | 80 | 23 | 16036 | 2547 |
CASP3,PIK3R1,ERBB2,AURKB,YES1,SPSB1,EGFR,RASA1,SLC9A2,WWP2,ARHGAP35,SOCS3,PLCG1,INSR,CASP7,IGF1R,HTT,DOK4,NFKBIA,AURKA,WWP1,ERBB3,SYK |
| 2.565e-03 | -5.97 | human chr12q23.1 | chromosome location | human chr12q23.1 | 24 | 8 | 26250 | 2805 |
GOLGA2P5,CDK17,ANKS1B,DEPDC4,ANO4,AMDHD1,CCDC38,UHRF1BP1L |
| 2.565e-03 | -5.97 | WEI_MIR34A_TARGETS | MSigDB lists | WEI_MIR34A_TARGETS | 144 | 34 | 17758 | 2588 |
TMEM184B,ZNF395,LGR4,ZCCHC24,CTSB,SOX9,SLC7A2,MGAT5B,FAM167A,TMCC3,PER2,B3GALNT1,C7orf49,NUP210,FAM46A,RALGPS2,SLC44A1,FUT8,KANK2,ACSL4,FLOT2,CRTAP,FAH,NAGPA,ACBD3,GALNT7,NPHP3,SNX12,GLCE,SGPP1,ALDH5A1,SWAP70,MPP2,PKIA |
| 2.567e-03 | -5.97 | response to inorganic substance | biological process | GO:0010035 | 431 | 86 | 16441 | 2455 |
CASP3,SLC25A24,NQO1,SLC25A13,NDRG1,IQGAP1,SOD2,COL18A1,P2RX7,CCNB1,HDAC6,SDC1,CALM2,CCND1,CPNE2,CYP1A1,PCNA,CDH1,STIM1,FOSB,DNM2,AKR1B1,TRPC1,CDKN1B,LRP11,S100A13,CYP1B1,PPIF,SIRT1,SOD1,DMTN,CASP9,ACO1,SLC11A2,LOXL2,ITPR3,ATP13A2,PTGS2,KCNMB4,STK26,AREG,ATP7B,LTA4H,ANXA11,KLF2,SCN5A,TRAF2,PRKAA1,MTL5,CALM3,ETS1,ICAM1,CALR,PDCD10,CA2,PTEN,CST3,SLC30A6,CD9,BAX,TFAP2A,IGFBP2,MAPK7,DUSP1,CALM1,GRIN1,GGH,FOS,RHOB,CYB5A,FAS,GPLD1,RASGRP2,FECH,IL1R1,PRDX3,HTT,NR4A3,OSER1,PKD2,ALG2,MAP3K5,TRPC3,PTGES,CYBRD1,EGLN1 |
| 2.570e-03 | -5.96 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_WS | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_WS | 39 | 13 | 17758 | 2588 |
CTGF,ITGB8,NDRG1,SOX9,FLOT1,CTNND1,USP1,TP53I11,SGCB,SYK,RHOB,PRDX4,SGPL1 |
| 2.570e-03 | -5.96 | PENG_GLUTAMINE_DEPRIVATION_UP | MSigDB lists | PENG_GLUTAMINE_DEPRIVATION_UP | 39 | 13 | 17758 | 2588 |
TOP2A,MMP15,DDB2,PPP2R5A,NR3C1,BCL9,PRKCI,ITPR2,PLCB2,CDC25C,BARD1,RASA1,H1FX |
| 2.572e-03 | -5.96 | glucose metabolic process | biological process | GO:0006006 | 146 | 35 | 16441 | 2455 |
GAA,INPPL1,ENO2,UGP2,SLC25A13,PRKAA1,WDTC1,CALM3,GALM,PRKACA,EPM2A,PER2,CALM2,PFKL,PIK3CA,GYS1,GOT1,BRAT1,PHKA2,PHKG2,PGM1,AKT1,PFKFB2,CALM1,PYGL,PDK3,PKM,IRS2,CRTC2,ONECUT1,ALDH5A1,PGM2L1,MDH1,PPP2R5D,DLAT |
| 2.573e-03 | -5.96 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | 347 | 70 | 17758 | 2588 |
TRIP10,MCOLN3,PDIA5,COL18A1,KCTD12,CCNB1,DDR1,IER3,KIAA1107,IMPAD1,EPHB4,TBC1D10B,XKR8,COL6A2,RIPK2,CELSR2,ATP1B1,C15orf39,CD40,ALDH5A1,NGFRAP1,TRIM45,PIEZO1,DMWD,PPP2R5D,GRN,SORT1,MPZL1,PEX6,GCAT,TSPAN15,ESRP1,FXYD3,CBLL1,JAG2,POMGNT1,MERTK,PARM1,FZD6,SSX2IP,LGALS3BP,NEO1,CORO1B,SNTA1,ANK1,KCNN4,OPN3,ERBB3,ITM2C,SLC16A5,WBP5,PCCB,HMGN5,TCFL5,MPP1,SCRIB,ZSCAN12,MEST,SNTB1,MFSD7,GNA11,CYB5A,CRISPLD2,NAAA,H1F0,PITPNA,WDR62,CCNB2,NCAPG2,XDH |
| 2.584e-03 | -5.96 | negative regulation of substrate adhesion-dependent cell spreading | biological process | GO:1900025 | 11 | 6 | 16441 | 2455 |
AP1AR,TACSTD2,MFI2,FBLN1,DMTN,CORO1C |
| 2.584e-03 | -5.96 | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP | MSigDB lists | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP | 812 | 147 | 17758 | 2588 |
SUN1,TMEM184B,TAP1,DNAJB11,UBE2Q1,C1orf198,NANS,ITPR2,MORF4L2,CENPN,BTG3,UBE2T,ARL1,IMPAD1,PPP1R16A,PAPSS1,RDH14,RGS5,PPP1CA,RNF26,TFG,IL10RB,ACBD3,MCFD2,SAV1,IDH1,RHEB,SEC14L2,IRX3,LRRC42,MID1IP1,SLC25A4,WIPI1,P4HA2,LRIG1,TDRD7,IARS2,ADIPOR1,KPNA2,CHPT1,GRN,PPP1R2,SEC61G,HLA-F,LMNA,CORO1B,MYO5C,ZCCHC17,PRICKLE4,RANBP1,AHCY,RFX5,HLA-C,FAM84B,STT3B,MYLIP,NDUFA12,KCTD3,CKAP4,EPHX1,PIGC,PRODH,MAPKAPK3,TESK1,LPGAT1,ANO6,PIP4K2C,BTN3A2,AMDHD1,C18orf8,SOX13,SERTAD2,TIMM8A,FAM83D,AURKA,SERPINB1,TMEM14A,FAM45A,DYNLRB1,MTM1,TUBB4B,PKP2,CCNA2,APIP,RNASEH2A,PDIA6,NAGA,TMEM9,CKS2,FRS3,SEC61B,ERLEC1,FZD4,CDC20,NUSAP1,ATP1B1,XRCC6BP1,GTF2A2,ZMPSTE24,AMZ2,PPP2R5A,SLC9A6,PEX2,CANT1,CBX7,DENND5B,MAN1A2,SH3D19,FLOT1,PSMD10,SBF1,TRIB2,NUCB2,RBP7,TIPRL,XPR1,COX7A2,RND1,IRAK1,GPC3,FAM20B,PRC1,CD9,DRAM1,CKS1B,TAGLN2,CNPY3,MSH6,CASK,PSMB4,ASPM,TEF,TCFL5,PARP4,BLVRA,RAB3IP,AIF1L,C4orf27,HLA-B,SWAP70,ZMYND19,CSTF2,ARFGAP3,ITGAV,NUP37,CYBRD1,JARID2 |
| 2.590e-03 | -5.96 | MODULE_75 | MSigDB lists | MODULE_75 | 394 | 78 | 17758 | 2588 |
IL15RA,NQO1,IL15,DNAJC3,GATA3,ERBB2,IL18,IL27RA,MGST2,SNN,PDGFB,FLT3,EMP2,MXD1,PDGFA,CTGF,IL6ST,CAPG,BCL6,TACSTD2,IFIT1,IL1RAP,LAMP3,MX1,CD55,PTGER4,CR2,ARHGDIB,ALCAM,EDNRA,MDK,FYN,AREG,P4HA2,MYLK,STAT1,IRF7,GRN,DYRK3,HLA-F,EPS8,SELL,SEPP1,ETS1,IL18R1,LGALS3BP,HLA-A,GBX2,TIMP1,CTSC,CYR61,KCNN4,CD22,DAPK1,HLA-C,RAG1,EPHX1,IFITM3,EMP3,RUNX3,CDK5R1,CD83,FAS,IL1R1,HLA-B,CD8A,BTG1,SEMA4D,CSF1,NFKBIA,NAB2,OSMR,NR4A2,GEM,CD81,AHR,CSRP2,IRF1 |
| 2.592e-03 | -5.96 | kinetochore | cellular component | GO:0000776 | 122 | 30 | 17570 | 2579 |
PLK1,REC8,ZWINT,CENPA,SPC25,HJURP,PPP1R12A,CENPC,SEPT6,CENPI,NDC80,ERCC6L,NUF2,KIF2C,AURKB,CCNB1,SPDL1,SKA1,CENPN,DCTN6,NEK2,KIF22,BUB1,CENPE,KNTC1,NDE1,NUP37,SGOL1,CBX5,NUP85 |
| 2.593e-03 | -5.95 | cell proliferation | biological process | GO:0008283 | 679 | 128 | 16441 | 2455 |
TXN,LGR4,IL15RA,CUL1,KIF2C,CYP1A1,PCNA,TGFBR3,CTNNB1,CTGF,ELF5,DLG1,IRF2,TACSTD2,LAMP3,PLK1,CR2,TFAP2C,LOXL2,GINS4,EDNRA,AREG,TBX1,MAP3K11,F2RL1,E2F8,GAB1,GRN,SOX9,RACGAP1,ZNRF3,MECOM,BMP2,DAZAP1,CYR61,BHLHE41,CTPS1,BRAT1,CD70,PIM1,WNT3A,SALL4,STAT4,SCRIB,ILK,C3orf58,EGFR,CDK5R1,CSF1,NAB2,APPL2,FAM83D,NDE1,DLGAP5,GRHL2,NF2,IL15,RPS6KA1,TP53,ERBB2,P2RX7,BCL2L1,OSR2,EMP2,APC2,STIL,FLT3,TNFSF9,MXD1,CCND1,NOV,ARTN,TACC2,KIF14,DIXDC1,TWIST1,TSPAN1,DVL2,CKS2,AKT1,RIPK2,FIGNL1,IGSF8,CD40,CDC25C,IRS2,FYN,STAT6,STAT1,NRG1,PDXK,PRKAR1A,BIN1,NKX3-1,POC1B,EPS8,NES,BTN3A1,GSTP1,FZD6,TEAD3,GBX2,PTEN,GPC3,BMP7,BAX,CKS1B,BUB1,ERCC2,CITED2,SYK,RASGRF1,WNT10B,TACC1,ASPM,RC3H2,FURIN,BCAR1,PITX2,ACVRL1,FGFR2,NR4A3,CSGALNACT1,ABCB1,OSR1,CD81,NCAPG2,MELK |
| 2.594e-03 | -5.95 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | 272 | 57 | 17758 | 2588 |
ANXA3,LTBP1,FBLIM1,ARAP3,TUBB4B,PSME2,BACE1,LRP4,CALM3,RACGAP1,CHAC2,ETS1,ANO1,CALM2,TOP2A,APOBEC3B,PSMD1,IRAK1,CALD1,PSMC2,TUBG1,NCAM1,TUBA4A,HMMR,CXXC5,PSMB4,PRSS23,CTNNAL1,TACC1,PBK,CALM1,MYEOV,EZR,NEURL1B,CDK1,PSMA4,COL12A1,MAP1B,CMTM7,STK17A,TNS4,IDE,STX10,RND3,AXL,UBE2D2,PGM2L1,FBXO44,KPNA2,DONSON,GDF11,F2RL1,CCNB2,PSMC1,ABCA1,ACOT7,KLF7 |
| 2.598e-03 | -5.95 | protein catabolic process | biological process | GO:0030163 | 566 | 109 | 16441 | 2455 |
FAF2,TRIM24,DNAJC3,PSME2,CUL4B,PTTG1,FBXO2,CUL1,P2RX7,UBE2Z,PSME1,MVB12B,CCNB1,HDAC6,RAD23A,PSMD1,KIF14,PSMC2,DAB2IP,TINAGL1,LGMN,PLK1,SIRT1,SEC61B,ERLEC1,FBXL16,AKT1,SPATA18,ITCH,USP18,CDC20,RNF11,BNIP3L,VPS4B,RNF165,AURKB,CCNF,CBL,RNF19B,CDK1,VCP,ZMPSTE24,TRIM9,DNAJC10,IDE,HPSE,PSMD3,WFS1,WWTR1,CHMP4B,AREL1,PSMC1,PINK1,HSP90B1,BACE1,CIT,DNAJB2,TRAF2,CTSB,JKAMP,PSMD7,PSMD10,CTSZ,NOTUM,ZNRF3,FBXO6,DNAJB9,WWP2,CAPN2,RNF128,CTSC,FBXO7,NEK2,FBXL14,UBE2J1,PCYOX1,WWP1,USP38,USP1,STT3B,ZRANB1,CTSD,MYLIP,PSMA5,UFD1L,USP31,PSMB4,AMFR,NUB1,UBE2A,FBXO9,FBXO8,TP53INP2,PSMA4,FBXO10,USP6,CTSL,CTSV,UBE2D2,AURKA,ARRB1,CTSA,YOD1,NDFIP1,UBE2C,RNF146,USP16,FBXW5,USP43 |
| 2.613e-03 | -5.95 | Choline metabolism in cancer | KEGG pathways | hsa05231 | 101 | 27 | 6908 | 1076 |
PLA2G4A,WASF3,PDGFC,AKT1,DGKQ,PIK3R1,DGKA,PLD2,PDGFB,FOS,EGFR,RHEB,DGKE,SLC44A3,DGKH,PDGFA,TSC1,PLCG1,RAC2,PLPP3,SLC44A1,PIK3CA,SLC44A2,PLD1,PIK3CD,DGKG,CHPT1 |
| 2.613e-03 | -5.95 | Choline metabolism in cancer | KEGG pathways | ko05231 | 101 | 27 | 6908 | 1076 |
PLA2G4A,WASF3,PDGFC,AKT1,DGKQ,PIK3R1,DGKA,PLD2,PDGFB,FOS,EGFR,RHEB,DGKE,SLC44A3,DGKH,PDGFA,TSC1,PLCG1,RAC2,PLPP3,SLC44A1,PIK3CA,SLC44A2,PLD1,PIK3CD,DGKG,CHPT1 |
| 2.616e-03 | -5.95 | V$ISRE_01 | MSigDB lists | V$ISRE_01 | 238 | 51 | 17758 | 2588 |
DDX58,GSDMD,SORBS1,MACC1,HLA-F,ETV5,DGKA,ETNK1,CACNA2D2,ERBB2,PRKACA,IL22RA1,DTX3L,CDKN2C,ADD3,DNAH6,NPNT,RRBP1,DUSP10,ADAM15,CDH3,TRIM21,IRF2,HLA-C,TECR,SCN2A,ARMCX6,PSMA5,PCGF5,KCNIP3,CXXC5,RIPK2,USP18,SH3BGRL,NUB1,SLC11A2,IFIT3,COL12A1,OPTN,CXXC4,TAPBP,MAP2,CCDC6,STAT6,AMMECR1,MAP3K11,OVOL1,FAM117A,IFIH1,CBX4,JARID2 |
| 2.625e-03 | -5.94 | pharyngeal system development | biological process | GO:0060037 | 18 | 8 | 16441 | 2455 |
HES1,ACVR1,NKX3-1,TBX1,GATA3,TGFBR1,ECE1,SIX4 |
| 2.625e-03 | -5.94 | regulation of B cell apoptotic process | biological process | GO:0002902 | 18 | 8 | 16441 | 2455 |
IRS2,PTEN,BCL6,BAX,FNIP1,AURKB,SLC39A10,BCL10 |
| 2.636e-03 | -5.94 | oesophagus-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-carcinoma-squamous_cell_carcinoma | 6791 | 1052 | 17775 | 2585 |
FAM160B1,IBTK,GRIK2,AK7,SLC25A13,HEXB,RET,CCNO,TGOLN2,BAIAP3,ISOC2,DPP8,SPSB1,CARD10,GRM5,CDKN2C,NPM2,MUC4,UBE2T,ATP13A3,DNM2,WBP4,TIAM1,CPE,ANKRD9,MGAT5,CCDC74A,DSTN,KDELR3,TMEM151A,TFAP2C,PRKAR2B,PNKD,ABR,PLCG1,MPRIP,ATP7B,TRAF3IP1,NOD2,RNASEL,STARD13,SCN5A,GGA1,ITGA6,MTL5,RAB23,COX6C,TTYH3,TFAP4,FLII,RAC2,ZCCHC17,FRY,MEGF8,FLRT3,FBXO7,SLAIN2,CADPS2,ALPK1,PANX2,SHARPIN,FHL2,KIF20B,ELK1,DPYSL4,SFXN5,GNA11,MAGED2,IL1R1,CACHD1,FNTA,SLC4A4,ETS2,DGAT2,CLMN,OSCP1,ADAMTS16,DMPK,DOCK9,APOO,KIAA1147,MUC16,ST5,CDH1,SH3BP1,TAX1BP3,RASGEF1A,MX1,SEC61B,COL6A2,PFKFB2,AGPS,ZNF618,TRIM7,GIGYF1,CCNB3,CORO1C,AXL,PNPLA6,FAM149A,ISOC1,HSP90B1,MPZL1,FAM189A2,GCAT,ESRP1,CCM2,OSGIN2,CTSZ,ZNF219,PLPPR4,IFT27,SLC25A45,ITGB8,IGSF9,KNDC1,MGAT4A,ZFAND4,PVRL4,PLSCR1,TACC1,PIK3R1,MRS2,CXorf57,PGBD1,RAB3IP,PLOD2,RAB11FIP2,SYT7,PLA2G15,ITGAV,OSR1,CMPK2,PHC1,TLL2,TMEM131,TNK1,KIAA1462,CNOT8,ARFGEF1,NDRG2,DNAJB11,TEX2,GALM,MGAT5B,ITPR2,SPTB,SUSD2,RPS6KA2,NUP210,CTNNB1,P4HB,IL6ST,SLC44A1,MITF,ABCA2,NTN4,KRT80,MARK1,CELSR2,CR2,CKAP2L,SESN1,DZIP1L,TNS4,PLEKHG6,PI4K2B,HS6ST1,KCNMB4,KLF11,TTC39C,TC2N,PARP12,DNAJB2,NCKAP1,ANO1,MYO5C,TNS3,FRAS1,KIF13B,ICAM5,FCHO1,MPHOSPH9,PCDH1,USP31,RGMB,ZNF320,MGAT4B,ZSCAN12,BCL2L13,RASGRP2,FOXD2,KBTBD2,PHLPP2,AKIP1,SEMA3A,CDAN1,USP43,RAD21,CTDSPL,TP53,RHPN2,P2RX7,BAHD1,EMP2,STIL,SYTL2,TTC21B,WDR44,TACC2,BCL6,ZDHHC23,CDH3,NOTCH3,OAS3,LMAN1,SULF2,ERLEC1,AKT1,ACO1,DAG1,ATP13A2,ZNF628,ABHD12,CHMP4B,IRF7,ZMAT1,BIN1,DYRK3,CDH22,TAB3,CTSB,SCD5,ERCC6L,GDF15,LBR,VPS26A,H1FX,SH2D4A,CD109,ALPP,TFAP2A,FAM63A,IL17RA,SYK,P2RX4,HES1,HMGN5,GUSB,DPP9,MAML2,COL7A1,USP6,DDX23,SCG2,E2F1,HIPK3,ARHGEF9,PKIA,GOLGB1,FAM171B,PNISR,LGR4,HSPG2,SSH1,VANGL1,C1orf198,CUL1,SLC9A7,ASPHD2,PAK6,ANKS6,STIM1,PIK3CA,KCNS3,POLL,SNX16,IRF2,SGCE,KIF13A,POR,PRIM1,GDE1,BMP1,PRDM5,SPRY4,FGD1,MRC2,DHPS,TBC1D1,TNFRSF19,S100A2,PSIP1,SH3RF2,DOPEY2,AIM1,DAPK1,PRKG1,TMEM51,ADCK2,CACNA1D,ZNF117,GPR161,TRAK2,GFPT1,SPATA20,GCC2,PRODH,PRSS23,CEP89,CALM1,DCHS1,PYGL,WHSC1,ATP8B3,SLCO4A1,FAAH,PELI2,MATN2,MPP2,FAM83D,ARAP1,AGBL5,SFMBT1,CABIN1,SAMD8,CDK18,ZBTB34,PER3,PLIN3,HOOK1,IFIH1,SPRED1,KIF3C,TCTN2,REPS2,DLGAP5,ST14,CCDC110,NDRG1,ATP2C2,FLT3,ART5,ZFYVE9,EPS8L2,CD46,TRANK1,EPHB4,PDE4D,RNASEH2A,MED30,ATG4D,DOCK4,COG2,UTRN,TMEM144,PYGO1,ATP1B1,CBL,ALCAM,ATP10D,FZD7,ZMPSTE24,COBL,MAMDC2,PLSCR4,DEPDC1,SLC41A1,EPS8,PBX3,NES,DNAH3,EFNB1,COX7A2,E2F7,FUT8,CD9,ERBB3,SLC16A5,MSH6,FARP2,PDGFC,ZWINT,ALDH2,B3GNT2,ZKSCAN2,FBXO9,DIAPH2,UBAC1,CDK5RAP1,CRTC2,DGCR2,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR62,ESPL1,CRYM,MPP5,ERP29,TRIM68,SIPA1L2,ARHGEF37,ANKFN1,CEP78,CTTN,MYRIP,BTBD3,IL1RAP,STK35,CYP1B1,ASXL1,ITCH,RGAG1,ARHGDIB,MAN2A2,TDRD7,CAPN1,PCSK5,NR2C2,ARAP3,PPP1R2,ZNF395,PPP1R12A,PYROXD2,ETV5,ABCG2,PM20D2,ADAMTSL4,SPP1,TYW3,CES2,PFKL,OCRL,COL6A1,MTMR10,LIMCH1,C10orf54,ETV7,CCDC88A,SNED1,SNX7,ELK3,SPA17,KIAA1109,HEATR5A,NUBP1,PDIK1L,C3orf58,RHPN1,SOX13,INSR,SPAG7,CTSA,SHROOM2,TMEM14A,JAK3,TOB1,SNX30,LMO7,NCKAP5,SORBS1,COL18A1,IL27RA,MRAS,OSR2,SAP130,ZNF687,CYP4F11,KIF14,NFKB2,UPF3A,PTPRU,CD40,TMTC2,PDHX,ARHGAP35,HSF4,STAT6,TLE1,RCAN2,SPTBN5,ABCA1,LNP1,KDELC2,GLIS3,GCLM,FBLIM1,ARHGEF11,ARHGEF7,SH3D19,SHPRH,SERPINB9,TGFBR1,COL4A5,INTS8,SBF1,ITGA2B,HDAC9,KIF5B,LLGL2,A4GALT,BMP7,TOX2,RRBP1,ACTA2,CLIP2,RPGR,MYO5A,PHF20L1,DCAF6,RC3H2,TTC7A,RUNX3,FAM73B,LEPR,ARHGAP24,SWAP70,FIBCD1,CSGALNACT1,ARRB1,GRAMD1C,ZMIZ1,AHR,ABCG1,CD33,ACACB,IL15RA,ADD1,TRIM24,AASS,MRPS15,FBXO2,CACNA2D2,NRG2,DHX8,SYTL4,KIF26A,BARD1,CA8,TP73,CALM2,ZYX,TGFBR3,RGS12,ARHGAP42,KIAA1107,DNAH6,CYP2S1,FUT1,PIK3CD,SEMA3G,ODF2L,SPEF2,NWD1,MTRF1L,LOXL2,F12,CYP4F3,COL12A1,TRIM47,WDR11,ANKRD6,DNM1L,LIMK1,MYLK,MAP3K11,SERPINB6,LSM14B,GAB1,TMTC3,CYP2J2,STRN4,SLC36A4,MERTK,ELF3,GNS,FAM189A1,CD22,ZIC5,FAM13B,SLC37A1,KIF20A,SALL4,STAT4,PLS1,MEST,CYB5A,PTPRF,NCOA3,HTT,ITPR1,DYSF,ALG2,DRP2,NDE1,TRPC3,ZNF502,SERPINB1,GRHL2,ACTR8,RGS20,PKP2,NUF2,PRSS22,RTKN2,RAB27B,ARL4D,CDKN2D,SCN3A,CAMSAP3,LGALS8,FZD4,SYNE2,PLEKHO1,NUSAP1,CDCA2,IRS2,PEX5,STX10,SLC9A6,WWTR1,INPP4B,TNRC6C,TAOK2,FARP1,PARP14,MAN1A2,GMCL1,ANO9,ETS1,KCNC4,PDIA4,NEO1,CAPN2,ANK1,ADD3,SLC27A6,IRAK1,ANKS1B,ALG13,CALD1,KCNK5,FDXR,ADAM15,PLEKHF1,MAPK11,ZNF230,WWP1,ITM2C,TPCN1,HCN3,AMOTL2,FMN1,FAM160A1,RAPGEF2,EIF5A2,ELOVL3,DBR1,PLEKHA7,EMP3,SNTB1,CRISPLD2,PITX2,GALNT3,CCDC6,ATXN7L3,CENPE,SHOX2,UNKL,AGRN,MCCC1,HDAC6,PIGL,NUP62CL,SHC3,LMAN2L,DDHD2,DUSP10,TLN2,ANO4,MYBL1,NEB,DDX59,CCDC38,ZNF462,PCGF5,MCTP1,ESYT1,ANLN,IDH1,PLEKHB1,IRX3,PLCH1,MAP2,DOLPP1,P4HA2,CTNND1,PIK3C2B,PIEZO1,POMT1,EPB41L4A,GLCCI1,ZCCHC24,ASAH1,RACGAP1,CNTNAP2,DOCK11,PGAP1,IL18R1,SSX2IP,CORO1B,RB1,VASP,KIAA0895,IGF1R,GATA2,EXOC8,TMEM8A,C9orf9,ABCC1,CHSY3,CYP26B1,WDR72,CORO2A,PCBP3,KBTBD8,UNC45B,ZDHHC3,G2E3,EPN3,COQ10A,PVRL2,ITGA7,PRPS2,LTBP2,ATP1B3,RNF146,FAM45A,UPF3B,UGP2,NF2,ZNF28,ERBB2,FAM198B,SLC7A2,LPIN3,CYP26A1,PER2,CDK14,LHX6,SCN2A,EGLN3,MINPP1,FAR1,CTH,SIRT1,CPD,TMTC1,CDC20,MYPOP,DUOX1,DNAJC10,PRRT4,RTN4RL1,PTK7,ADAMTS14,ZBTB6,AIFM3,NDST3,ZNF701,GSDMD,COL9A3,PACSIN2,TRAPPC10,MACC1,PSMD10,SELL,GABRG2,JAG2,CEP97,MAGEE1,TLE6,IGDCC4,HMMR,MLEC,PSMB4,IFITM3,AMFR,PPARA,FXR2,AKAP3,FNDC3A,BCAR1,BANK1,FAT4,SERPINA1,ZMYND19,TMC5,CDCA7L,ACADM,SAT2,DIS3L,SUN1,GAA,ACVR1,PPP4R4,ATP8A1,KLC2,TAP1,PLXNA1,CENPN,CHST2,ELMO2,PRICKLE3,STEAP2,AOX1,ATRNL1,SMYD5,XKR8,ORAI2,CASP9,TNS1,CCNF,ZFAND5,TP53I3,ULK2,ARHGEF26,AHRR,PLK2,NKD1,UNC5B,TANC2,RTN3,LZTS1,DLAT,CDK17,INPPL1,FRMD4A,CALB2,DGKQ,SLC25A27,NOTCH2,ISYNA1,MECOM,PIK3AP1,NECAB3,BDH1,RUNDC3B,SORL1,CD70,CTSD,PIKFYVE,EEF1D,RIMS2,IGSF3,FADS2,B3GNT7,B9D2,TBC1D8B,ANO6,PTPRH,KCTD20,VEZT,PKM,KDM3A,RASA1,FRMD4B,FAS,PRKAG2,SLC4A3,PCDH19,NR4A2,EFNA1,MAP3K5,PKD1L2,PLA2G4A,FRMPD3,PLEKHG3,CEP70,TMEM217,TRIP10,RPS6KA1,IQGAP1,IRX4,NUDT12,GNB2,APLP2,CYHR1,FAM46A,TNPO2,DAB2IP,PHKA2,TBC1D10B,MYO5B,CDKN2AIP,CAPN6,LYRM1,TEP1,PRKCQ,C15orf39,SP4,ZNF469,NIN,FYN,STAT1,KIAA1804,NRG1,ZC3H12B,NR3C2,DENND5B,MRPS9,WASF3,NUDT6,SLC16A14,ATP9A,GPR180,TEAD3,C16orf59,PHF7,OXCT1,PTEN,ATP8B1,MAP3K7,CNPY3,SPRY2,NCOA2,SMC4,RASGRF1,ARAP2,CASK,ERMAP,TEF,LRRC1,GPLD1,RGS9,MAMDC4,PRDX3,AMMECR1,PGM2L1,GRIN2D,ETAA1,ARSB,NCAPG2,SLC25A38,OCLN,ESYT2,JARID2,EXPH5,PTCHD4,SH3KBP1,ABCD4,CHPF,ARHGEF10L,LRRC6,ZCCHC12,PHTF1,DLG1,ANKRD12,POF1B,SUN3,MYH14,SOD1,TRIM8,SYNE3,FOPNL,ROR1,ADRBK2,EDNRA,ARHGEF19,CCDC74B,APBA2,PPP2R5D,ASL,SAMD9,PHLPP1,AIM1L,ZNF432,CA2,LRRN2,EBF4,FNIP1,ZNF692,NCEH1,ACAD8,ALS2CL,HP1BP3,PARD3B,OXR1,GYLTL1B,FBXO8,RNF113A,MUM1L1,EGFR,GLCE,GNAS,ONECUT1,TSC1,CGREF1,ALPK3,KIF12,KLF7,ZSWIM5,ABCG4,GMPR,MORC4,MICALL2,ARHGEF16,SS18,KCTD15,FRYL,SMO,STEAP3,F2R,LOXL1,PDIA6,SCYL3,HSPA2,MAP3K3,GCA,ERBB2IP,SNAPC2,DOCK5,BFSP1,PEX2,CYP2U1,PLXND1,AKNA,SGOL1,LIFR,SORT1,JKAMP,AES,NOTUM,TRMT2B,ZNF212,SNX13,KIAA0319,TRIM3,HSPA13,IQGAP3,ASPM,LRRC66,MBNL3,POLD3,MPV17L2,SPAG1,MAP1B,DHRS2,ZNF596 |
| 2.636e-03 | -5.94 | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | MSigDB lists | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | 155 | 36 | 17758 | 2588 |
ZNF395,EPAS1,CTSB,EPHA4,DSE,DHRS3,SCML1,IER3,DAPK2,CYP1A1,SLC16A6,RGS3,CD9,MAPK7,TMBIM1,GM2A,CYP1B1,QSOX1,TIMP2,PRSS23,MPP1,CDA,COL7A1,TNS1,BLVRA,DUSP4,SLCO4A1,HPSE,MYLK,NOD2,NRG1,PTGES,ABCA1,MAFF,RRAGD,ABCG1 |
| 2.636e-03 | -5.94 | HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 | MSigDB lists | HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 | 155 | 36 | 17758 | 2588 |
ST13,DLGAP5,CD63,FOXM1,ERBB2,HMGN3,COX6C,PDGFB,PSIP1,CCND1,KIF5B,CDKN2C,BTG3,PCNA,CTGF,ITGB8,CTNNB1,MSH2,CKS1B,ARVCF,EPHB4,HP1BP3,GPX4,FAH,SEPHS1,SOD1,CXXC5,PRSS23,YES1,CBL,ALCAM,ENPP1,TIMP3,PPP1CB,TOB1,IRF1 |
| 2.651e-03 | -5.93 | CRMP1 (collapsin response mediator protein 1) | protein interactions | 1400 | 99 | 27 | 16036 | 2547 |
MOB4,ALDH2,RHOA,AMFR,SERPINB9,SAT1,GNE,UBE2A,CDCA8,CUL1,DNAJB11,FTH1,LRRC1,DUSP4,VCP,CORO1B,FAS,DPYSL3,SWAP70,PAFAH1B3,HTT,DPYSL2,OTUD6B,TFG,SPRY2,EEF1D,SEPHS1 |
| 2.651e-03 | -5.93 | JAK1 (Janus kinase 1) | protein interactions | 3716 | 99 | 27 | 16036 | 2547 |
PLA2G4A,SIRT1,PLAUR,INPP5D,PIK3R1,ERBB2,AGO4,IL27RA,TEC,EGFR,ELF3,SOCS3,IRS2,DTX3L,MDK,PLCG1,INSR,IGF1R,JAK1,STAT6,IL6ST,PLCG2,STAT1,OSMR,ARRB1,JAK3,SYK |
| 2.656e-03 | -5.93 | Aurora A signaling | Pathway Interaction DB | aurora_a_pathway | 31 | 14 | 2227 | 480 |
CENPA,AKT1,DLGAP5,TACC1,ARHGEF7,NFKBIA,TDRD7,TP53,AURKA,AURKB,PRKACA,PPP2R5D,RASA1,CKAP5 |
| 2.657e-03 | -5.93 | negative regulation of protein kinase B signaling | biological process | GO:0051898 | 34 | 12 | 16441 | 2455 |
LEMD2,SIRT1,BANK1,PTPRJ,IGF1R,PTEN,DLG1,PRKCDBP,GPER1,PHLPP1,DAG1,XDH |
| 2.658e-03 | -5.93 | CHUK (conserved helix-loop-helix ubiquitous kinase) | protein interactions | 1147 | 133 | 34 | 16036 | 2547 |
TRAF2,TP53,CUL1,TGFBR1,TP73,CCND1,IRAK1,CTNNB1,PRKCI,NOTCH3,PPP1CA,MYH14,MAP3K7,NFKB2,EGLN3,EBAG9,DUSP1,NLRP4,RIPK2,AKT1,SHARPIN,PRKCQ,ERBB2IP,CD40,MYL12A,BCL10,NCOA3,HTT,NFKBIA,NLRC5,MAP3K11,AURKA,HSPB1,NR2C2 |
| 2.666e-03 | -5.93 | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | MSigDB lists | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | 72 | 20 | 17758 | 2588 |
DDX58,CCNE2,MX1,IGFBP6,ABCG2,PTGER4,HERC5,SAMD9,IFIT3,HERC6,CRISPLD2,NOV,TIMP3,HPSE,FAM46A,ALDH1A3,SORL1,IFIT1,SEMA3A,IFIH1 |
| 2.666e-03 | -5.93 | MORI_PRE_BI_LYMPHOCYTE_DN | MSigDB lists | MORI_PRE_BI_LYMPHOCYTE_DN | 72 | 20 | 17758 | 2588 |
KLF2,LPGAT1,CASP9,SAT1,ERP29,AKIRIN1,GNS,BTG1,ATP6V0B,TMEM50B,RALGPS2,CD22,ZFP36,FAM3C,AIM1,NFKBIZ,RGS14,TRAF5,CAPN1,JARID2 |
| 2.666e-03 | -5.93 | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | MSigDB lists | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | 72 | 20 | 17758 | 2588 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,DUSP4,ELK1,FOS,CDK1,MAPKAPK2,RPS6KA2,IRAK1,NFKBIA,NOD2,IRF7,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 2.669e-03 | -5.93 | INSP3RECEPTR | prints domains | PR00779 | 3 | 3 | 4759 | 661 |
ITPR2,ITPR3,ITPR1 |
| 2.669e-03 | -5.93 | NUCLEARECPTR | prints domains | PR01284 | 3 | 3 | 4759 | 661 |
NR4A2,NR4A1,NR4A3 |
| 2.674e-03 | -5.92 | PLK1 signaling events | Pathway Interaction DB | plk1_pathway | 44 | 18 | 2227 | 480 |
PLK1,RHOA,KIF20A,PPP1R12A,CDC20,ERCC6L,NDC80,CCNB1,BORA,CDC25C,CDK1,WEE1,TUBG1,AURKA,PPP1CB,BUB1,CENPE,SGOL1 |
| 2.675e-03 | -5.92 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | 92 | 24 | 17758 | 2588 |
PSMB4,NFKBIE,AKT1,NR4A1,PSME2,CASP9,PSMD7,PSMD10,CUL1,RASGRP3,PSME1,PHLPP1,PSMA4,BCL10,PSMD1,PTEN,PSMD3,NFKBIA,PSMC2,CDKN1B,MAP3K7,PSMC1,RASGRP1,PSMA5 |
| 2.678e-03 | -5.92 | ZHANG_BREAST_CANCER_PROGENITORS_DN | MSigDB lists | ZHANG_BREAST_CANCER_PROGENITORS_DN | 139 | 33 | 17758 | 2588 |
HSP90B1,PPP1R2,CAST,HDAC11,KIF23,IL18,COMMD5,BCAP31,CXCL16,SCNN1A,DNPEP,RANBP1,SRR,VAT1,MDFIC,TACSTD2,MTMR11,PIK3CD,CPD,DCAF6,ZC3H11A,FNDC3A,DAG1,SOCS3,TAPBP,CACHD1,CSF1,ARRDC1,NFKBIZ,SPRY4,ANXA9,PLOD3,GLCCI1 |
| 2.683e-03 | -5.92 | CCTGCTG,MIR-214 | MSigDB lists | CCTGCTG,MIR-214 | 227 | 49 | 17758 | 2588 |
CPEB4,TRIP10,BACE1,KLC2,FAM134A,WDTC1,HMGN3,TGOLN2,CDIPT,SEPT4,PICK1,RAB15,PIK3AP1,ANKS1B,DOK4,VASN,RIMS3,PPME1,LHX6,ARVCF,CRY2,FAM84B,PIM1,NPTXR,TBC1D10B,CXXC5,ING1,CELSR2,ITCH,OXR1,PANK1,GRIN1,TFAP2C,FAM133B,VEZT,GALNT7,PELI3,CBL,SNX12,TCN2,FZD7,PGF,PTER,CSF1,DOLPP1,CHMP4B,FBXW5,DOCK9,RGMA |
| 2.692e-03 | -5.92 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | 188 | 42 | 17758 | 2588 |
SLC25A24,LGALS3,GNPDA1,TUBB4B,SERPINB9,GTF3A,BARD1,HLA-A,NEO1,WEE1,CCNA2,PIK3AP1,NECAB3,RANBP1,TOX2,PRC1,NEK2,PLK4,CKS1B,KIF22,ALDH7A1,SGCB,SNX10,TIAM1,TSPAN33,MLEC,PLSCR1,PBK,MBNL3,AURKB,PIF1,ANLN,KIF11,ENDOD1,CASP7,SERPINB6,MRPS28,GEM,NDE1,C17orf75,E2F8,CSRP2 |
| 2.692e-03 | -5.92 | GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_UP | 188 | 42 | 17758 | 2588 |
CCNE2,CDK17,DYRK3,PTTG1,MIER3,SYTL4,HES2,SLC20A1,PGAP1,TMEM63A,PDGFA,CYP1A1,MTMR10,HSPA13,TAGLN2,TMBIM1,WBP5,NLRP4,POU6F1,SYPL1,SEC23A,LPGAT1,S100A4,VAMP3,PYGL,CALCRL,HEATR5A,GIGYF1,RHOB,LDLRAP1,NR1D2,UBE2D2,ARAP1,RHOBTB2,PGM2L1,UACA,RCAN2,HS3ST3B1,ARSB,CD81,TOB1,KLF7 |
| 2.692e-03 | -5.92 | GSE17721_CTRL_VS_LPS_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_12H_BMDM_UP | 188 | 42 | 17758 | 2588 |
CCNI,SPC25,GNPDA1,CKAP2,ABCG2,GMPR,TESK2,TGFBR1,MRAS,NANS,MGST2,FAM81A,XPR1,SLC25A45,PCNA,MDM1,IL6ST,BDH1,ADAM15,ABCD1,HMGCL,MED22,GPX4,SEC61B,GUSB,PBK,MBNL3,KIF1C,KIF13A,ERBB2IP,BCL2L13,CDK1,C4orf27,GIGYF1,OSBPL2,TMEM50B,PROM1,NR4A3,CTSA,PLD1,CCNB2,CSRP2 |
| 2.692e-03 | -5.92 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 188 | 42 | 17758 | 2588 |
BIN1,SLC25A24,PPP1R12A,INPP5D,DGKA,NOTCH2,SNN,TRIB2,FAM111A,ADD3,FRY,RPL39,FAM13B,AIM1,SORL1,RFX5,PIK3CD,CDKN2D,SNX10,SYPL1,GCA,PTPN18,ING1,TCFL5,CXorf57,CR2,KIF13A,ARHGDIB,MRPS35,SRSF5,ESYT1,POLD3,RASGRP2,SGPP1,ENDOD1,ARHGAP24,RPL12,SLC4A4,DCK,STAT6,CSF1,PKIA |
| 2.692e-03 | -5.92 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | 188 | 42 | 17758 | 2588 |
BIN1,KLF2,SIGIRR,ACACB,KIF3C,HECA,ZNF395,TSC22D3,TMX4,ARL4C,NUCB2,FAM46C,MARCH8,ADD3,GNB5,ZFP36,MCF2L,MGAT4A,FUT8,SORL1,SEMA3G,PDE4D,SUN2,S100A4,PCBP3,SH3BGRL,BNIP3L,GRIN1,CR2,PRKCQ,NUSAP1,FOS,NDRG3,RASGRP2,MMP15,IRS2,PLCG1,NGFRAP1,PIAS2,PPP1CB,NR3C2,TOB1 |
| 2.692e-03 | -5.92 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_DN | 188 | 42 | 17758 | 2588 |
SCN5A,ACVR1,MRC2,HSPG2,ATP8A1,NKRF,PLA2G16,OAT,BAHD1,TEAD3,TFAP4,RB1,PCNA,NUP210,STIM1,KIF14,DAPK1,CD9,TAX1BP3,BUB1,ZNF230,DIXDC1,PLCB2,ATP2B1,MLEC,ASXL1,CORO2A,KIF11,BCAR3,OSBPL2,GPRC5B,RCBTB2,RBL1,RAB11FIP2,DHRS2,NAT1,SFMBT1,GDF11,PLOD3,RPL22,C17orf75,JARID2 |
| 2.692e-03 | -5.92 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN | 188 | 42 | 17758 | 2588 |
CCDC109B,PARP12,IL15RA,IL15,ATP8A1,TAP1,SOD2,SELL,HERC5,CBLL1,LGALS3BP,TYMP,NUP210,SP100,RGS3,TRIM21,KIF22,PIM1,SNX10,CKAP4,GPR161,SUN2,ALDH2,IFITM3,UXT,TCF7,CD40,IFIT3,RASGRP2,SERPINA1,ITPR1,STAT1,CSGALNACT1,CCDC69,FAM117A,IRF7,APBA2,APOL2,RPS6KA3,IRF1,EHD1,ABCG1 |
| 2.696e-03 | -5.92 | GSE2706_UNSTIM_VS_2H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_R848_DC_DN | 177 | 40 | 17758 | 2588 |
IL15RA,SERPINB9,SDC4,TAP1,P2RX7,HERC6,DUSP5,ICAM1,BTG3,GRHL1,ALG13,DRAM1,PLAUR,STAT4,RAPGEF2,LYRM1,PTGER4,BTBD19,RAB3IP,PIM3,IFIT3,TP53INP2,SOCS3,GALNT3,PTGS2,BTG1,CDCA4,UAP1,MFSD2A,NFKBIA,NR4A3,NFKBIZ,HS3ST3B1,EFNA1,GEM,CMPK2,ESPL1,MAFF,EHD1,FAM134B |
| 2.699e-03 | -5.91 | REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE | 77 | 21 | 17758 | 2588 |
PLK1,PSMB4,PSME2,PTTG1,CDC20,PSMD7,CUL1,PSMD10,PSME1,AURKB,CCNB1,CDK1,PSMA4,CCNA2,PSMD1,PSMD3,PSMC2,AURKA,UBE2C,PSMC1,PSMA5 |
| 2.699e-03 | -5.91 | AGGGCCA,MIR-328 | MSigDB lists | AGGGCCA,MIR-328 | 77 | 21 | 17758 | 2588 |
LGR4,NR3C1,PTPN9,WDTC1,ARL4C,TESK2,UBE2Z,FAM133B,TTYH3,SIX4,ULK2,NRP2,PRX,DPYSL3,PAK6,SERTAD2,CSNK1G1,ZNF704,ZC3H12B,PIM1,FGD1 |
| 2.699e-03 | -5.91 | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | MSigDB lists | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | 77 | 21 | 17758 | 2588 |
RASGRF1,TIMP2,PRSS23,EPAS1,PIK3R1,ARHGDIB,HOXB2,PPP2R3A,LCP1,TMEM50B,CASP7,TGFBR3,IGF1R,PLA2G15,RAB31,NR4A3,SGK1,NTN4,NRG1,ERBB3,IL1RAP |
| 2.699e-03 | -5.91 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12 | 77 | 21 | 17758 | 2588 |
ALDH2,S100A11,SLC39A8,PLEKHO1,EMP3,CAPNS1,GGH,PSME1,SNAPC2,NTAN1,IDH1,LGALS3BP,MAGED2,MDK,CYHR1,OXCT1,IARS2,AHCY,CHPT1,RBMS2,CKS2 |
| 2.699e-03 | -5.91 | V$AP1_Q6 | MSigDB lists | V$AP1_Q6 | 244 | 52 | 17758 | 2588 |
CMAS,LRRFIP2,SCOC,CAMKK1,ETV5,PSMD7,NDRG2,RNF182,DHRS3,PRR7,SLC35E4,LTBP3,ZNF385B,LMNA,CDK14,BMP2,PAK6,VASP,IGSF9,SHC3,NECAB3,SLC16A6,ABCA2,ABCD1,TAGLN2,TINAGL1,TUBA4A,MDFI,SMARCA2,TRIM8,CASK,MARK1,ELK3,DSTN,PTPRH,DCHS1,KBTBD8,TMEM151A,CAPNS1,ATP1B1,KDM3A,ZFAND5,MPRIP,TBC1D17,TMEM54,MAP2,S100A5,RCAN2,EFNA1,UBE2C,COBL,DMPK |
| 2.699e-03 | -5.91 | V$TEF_Q6 | MSigDB lists | V$TEF_Q6 | 244 | 52 | 17758 | 2588 |
LMO7,SPRED1,PAX6,CAST,ETV5,C5orf30,SLC20A1,PCBP1,HOXB2,HPCAL4,C1orf116,GRM5,GBX2,NEO1,CCND1,IGF1R,RALGPS2,FRY,GRHL1,PPP1R10,DPYSL2,RGS3,ALG13,KCNS3,TWIST1,CACNA1D,SCN2A,SPRY2,DOCK4,TRIM8,USP18,CDYL,CBX6,ARHGDIB,EBF2,NFIX,DHX32,NIN,DNAJC10,GPRC5B,PDLIM3,KLF12,WIPI1,COL13A1,MAP2,PELI2,PSMD3,MAL2,CDAN1,NDFIP1,TOB1,ARNT |
| 2.701e-03 | -5.91 | cell-type specific apoptotic process | biological process | GO:0097285 | 90 | 24 | 16441 | 2455 |
CASP3,AKT1,GRIK2,CASP9,TP53,JAG2,BCL2L1,PKN1,RHOB,FAS,BCL10,CTSL,RB1,RPS6KA2,HTT,SIVA1,TBX1,BAX,E2F1,DAB2IP,ERBB3,ARF6,SCN2A,DMPK |
| 2.708e-03 | -5.91 | Metabolism | REACTOME pathways | R-HSA-1430728 | 1691 | 292 | 8202 | 1235 |
GAA,ACACB,SLC35D2,TXN,HSPG2,AASS,AK7,SLC25A13,PNPLA2,HEXB,MMADHC,CACNA2D2,PSME1,PLA2G16,OAT,CHST2,CALM2,TYMP,HELZ2,PSMD1,CYP1A1,CTGF,CYP2S1,SLC46A1,PIK3CA,AOX1,KCNS3,DNM2,PIK3CD,ACOX2,PPP1CA,CDA,MGAM,PRKAR2B,SLC25A5,CYP4F3,SGPP1,SLC44A3,KDSR,ENPP1,PLCG1,SLC25A4,BMP1,ITPKA,PDPR,DLAT,INPPL1,ALDH6A1,CYP2J2,SLC25A27,NDUFA4,ISYNA1,COX6C,GNS,ATP5H,BDH1,CTPS1,CACNA1D,PIKFYVE,NDUFA12,PHKG2,NUP85,MCCC2,EPHX1,FADS2,B3GNT7,PRODH,LPGAT1,CALM1,FHL2,PYGL,PKM,SPTLC2,GNA11,PSMA4,CYB5A,NT5C2,NCOA3,PRKAG2,FAAH,DCK,ITPR1,DGAT2,MDH1,B4GAT1,NUP58,XDH,PLA2G4A,MTM1,SLC2A4,PAPSS2,NQO1,INPP5D,IQGAP1,ETNK1,MGST2,PRKACA,MOCS1,CYP39A1,GNB2,EPM2A,CDS1,ACSL4,LGMN,PHKA2,SULT2B1,MED30,GPX4,SEC23A,PFKFB2,AGPS,SAT1,PANK1,COX11,ITPR3,COX20,ALDH3B1,CDK19,ACAD10,WWTR1,INPP4B,PPP1CB,SLC27A1,HS3ST3B1,PDXK,B4GALT3,PRKAR1A,GALK1,SDC4,PLD2,SPR,GSTP1,TEAD3,SGPL1,GNB5,OXCT1,PTEN,ARSG,GPC3,FDXR,SLC44A2,ERCC2,NCOA2,MED22,OPLAH,PCCB,B3GNT2,SHMT1,ALDH2,PIK3R1,ELOVL3,BLVRA,ARSK,CPTP,LDLRAP1,ACADSB,SLC35B3,ABCB1,NUP37,ARSB,ACOT7,CCNC,AGRN,CRYM,CPT2,MCCC1,PHOSPHO1,ITPR2,CDIPT,SDC1,ECI1,CHPF,ABCD4,INPP5E,NUP210,GRHL1,P4HB,SLC44A1,PAPSS1,PSMC2,AKR1B1,TECR,CYP1B1,CERS2,CCBL2,IDH1,TCN2,PI4K2B,HS6ST1,PLCH1,HPSE,AGPAT2,PIK3C2B,GLA,CHPT1,PSMC1,PPP2R5D,HS6ST3,PRKAA2,FAM213B,ELOVL7,ABCG2,PSMD7,ASL,CALM3,ASAH1,B4GALT4,CA2,CES2,PFKL,OCRL,AHCY,ACAD8,FAR2,PLCB2,ALDH3A2,PSMA5,ABCC1,CHSY3,CYP26B1,PDK3,NUBP1,AMDHD1,GLCE,GNAS,FECH,MAPKAPK2,NUDT16,FA2H,PLPP3,PRPS2,CTSA,PLD1,UGP2,PSME2,GMPR,LPIN3,EXT2,CYP26A1,COX14,CYP4F11,FABP6,PLCG2,GYS1,GOT1,APIP,ETHE1,MINPP1,FAR1,GM2A,CHP1,CTH,RFK,AKT1,GLO1,PDHX,DUOX1,PTGS2,PSMD3,MAOA,CYP2U1,ST3GAL1,LTA4H,ABCA1,NDST3,GCLM,CDS2,ENO2,HAL,BLVRB,PSMD10,DSE,LBR,ZDHHC21,ALDH7A1,HMGCL,ABCD1,FAH,B3GALT6,HMMR,PGM1,PSMB4,GUSB,GCLC,PPARA,DDAH1,NAT1,CSGALNACT1,GLB1,ACADM,PTGES,ABCG1 |
| 2.709e-03 | -5.91 | negative regulation of protein import | biological process | GO:1904590 | 61 | 18 | 16441 | 2455 |
NFKBIE,THRA,LITAF,RAB23,PSMD10,APC2,NOV,CABP1,BMP7,WWTR1,NFKBIA,DAB2IP,PKD2,MDFIC,MAPK7,PKIA,CHP1,MDFI |
| 2.709e-03 | -5.91 | negative regulation of cyclin-dependent protein kinase activity | biological process | GO:1904030 | 61 | 18 | 16441 | 2455 |
PLK1,CASP3,CDKN1C,DNAJC3,TRIB2,MAPK8IP1,SOCS3,CDK5RAP1,TFAP4,CAMK2N2,PTEN,FBXO7,CDKN1B,HEXIM2,UBE2C,PKIA,CHP1,SOCS5 |
| 2.709e-03 | -5.91 | stem cell proliferation | biological process | GO:0072089 | 61 | 18 | 16441 | 2455 |
WNT10B,ASPM,NES,RACGAP1,ZNRF3,TEAD3,MECOM,BMP2,CTNNB1,ARTN,FGFR2,GPC3,BMP7,ABCB1,STAT1,OSR1,WNT3A,NDE1 |
| 2.709e-03 | -5.91 | negative regulation of protein import into nucleus | biological process | GO:0042308 | 61 | 18 | 16441 | 2455 |
NFKBIE,THRA,LITAF,RAB23,PSMD10,APC2,NOV,CABP1,BMP7,WWTR1,NFKBIA,DAB2IP,PKD2,MDFIC,MAPK7,PKIA,CHP1,MDFI |
| 2.709e-03 | -5.91 | REACTOME_L1CAM_INTERACTIONS | MSigDB lists | REACTOME_L1CAM_INTERACTIONS | 82 | 22 | 17758 | 2588 |
SCN5A,RPS6KA1,EZR,ALCAM,RANBP9,SPTB,EGFR,ITGA2B,NRP2,CNTNAP1,RPS6KA2,ANK1,DPYSL2,DLG1,DNM2,SPTBN5,ITGAV,SCN2A,DLG3,NCAM1,L1CAM,RPS6KA3 |
| 2.709e-03 | -5.91 | RECEPTOR_SIGNALING_PROTEIN_ACTIVITY | MSigDB lists | RECEPTOR_SIGNALING_PROTEIN_ACTIVITY | 82 | 22 | 17758 | 2588 |
MAP3K3,BAG4,ACVR1,ACVR1C,ERBB2,MAPK4,TGFBR1,MAP3K6,INSR,IRAK1,ACVRL1,STAT1,MAP3K9,MAP3K11,CDKN1B,MAPK11,MAPK13,MAP3K7,MAP3K5,MAPK7,ARNT,MAPK12 |
| 2.715e-03 | -5.91 | cadherin binding | molecular function | GO:0045296 | 30 | 11 | 16491 | 2452 |
EPCAM,CD46,P2RX4,PROM1,CTNNB1,CTNNAL1,NDRG1,FXYD5,CTNND1,CDK5R1,NEO1 |
| 2.729e-03 | -5.90 | glial cell differentiation | biological process | GO:0010001 | 136 | 33 | 16441 | 2455 |
EMX1,WASF3,NDRG1,HDAC11,SOX9,ERBB2,MPP5,DNER,PICK1,CDKN2C,CTNNB1,PTEN,TFAP2A,CD9,SMO,DUSP10,ERBB3,ERCC2,HES1,SOD1,RHOA,AKT1,ILK,DAG1,NFIB,NFIX,PTPRJ,FA2H,PLPP3,NAB2,NRG1,SOX8,DRD1 |
| 2.733e-03 | -5.90 | Regulation of actin cytoskeleton | KEGG pathways | hsa04810 | 214 | 49 | 6908 | 1076 |
MYL9,PPP1R12A,SSH1,ARHGEF7,IQGAP1,ITGA6,MRAS,NCKAP1,PDGFB,APC2,FGF19,ITGA2B,PDGFA,PAK6,RAC2,ITGB8,ITGA3,PAK2,PIK3CA,MYH14,PIK3CD,PPP1CA,IQGAP3,PIKFYVE,F2R,TIAM1,SSH3,PDGFC,RHOA,PIK3R1,PIP4K2C,DIAPH2,EZR,CYFIP2,BCAR1,MYL12A,EGFR,ARHGAP35,FGFR2,ITGA7,LIMK1,FGF18,MYLK,PPP1CB,ITGAV,ARPC2,MYL12B,ARHGEF4,FGD1 |
| 2.733e-03 | -5.90 | Regulation of actin cytoskeleton | KEGG pathways | ko04810 | 214 | 49 | 6908 | 1076 |
MYL9,PPP1R12A,SSH1,ARHGEF7,IQGAP1,ITGA6,MRAS,NCKAP1,PDGFB,APC2,FGF19,ITGA2B,PDGFA,PAK6,RAC2,ITGB8,ITGA3,PAK2,PIK3CA,MYH14,PIK3CD,PPP1CA,IQGAP3,PIKFYVE,F2R,TIAM1,SSH3,PDGFC,RHOA,PIK3R1,PIP4K2C,DIAPH2,EZR,CYFIP2,BCAR1,MYL12A,EGFR,ARHGAP35,FGFR2,ITGA7,LIMK1,FGF18,MYLK,PPP1CB,ITGAV,ARPC2,MYL12B,ARHGEF4,FGD1 |
| 2.740e-03 | -5.90 | positive regulation of gene expression | biological process | GO:0010628 | 1690 | 292 | 16441 | 2455 |
ACVR1,TRIM24,LGR4,TRIM5,DNAJC3,HEXB,RET,GATA3,IL18,MORF4L2,CAMK1D,CCNB1,TP73,HELZ2,CTGF,ZFP36,IL31RA,FOSB,DNM2,IRF2,PIK3CD,NEK4,SMARCA2,TNIP1,TFAP2C,F12,LDB2,SAV1,ARF4,AHRR,PIAS3,TBX1,NOD2,HDAC1,RNASEL,TRAF5,F2RL1,E2F8,HOXC13,DDX58,KLF2,CDKN1C,ITGA6,SOX9,PRKAA1,PSIP1,LMNA,MECOM,ELF3,TFAP4,CALR,ITGA3,CYR61,MYDGF,MAPK7,NUP85,RIMS2,MFI2,SALL4,STAT4,PYM1,FHL2,MYBL2,ELK1,ILK,TP53INP2,KDM3A,NFIB,NCOA3,SERTAD2,ETS2,SETD3,PIAS2,NR4A2,RPS6KA3,TMEM173,IRF1,ARMCX3,GRHL2,THRA,RPS6KA1,CD46,CCNA2,CDH1,SP100,DAB2IP,ETV4,MYT1,MED30,PSRC1,RIPK2,FZD4,FOXJ2,PRKCQ,PYGO1,GTF2A2,EBF2,FZD7,NFIX,WWTR1,STAT1,KLF5,NRG1,ARNT,ATMIN,TNRC6C,NKX3-1,CKAP2,TRAF2,PBX3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,E2F7,PDCD10,ITGB8,IRAK1,PTEN,MCF2L,MAPK11,ERCC2,CITED2,MAP3K7,SPRY2,TRIM62,NCOA2,CASK,PLSCR1,BCL9,TEF,PIK3R1,EIF5A2,GRIN1,YES1,FOS,ABLIM2,TXK,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,NR1D2,ACVRL1,NR4A3,GPER1,HMGA1,FZD5,OSR1,CD81,USF2,SHOX2,FOXA1,USP16,RGMA,CCNC,EPAS1,AGRN,ERP29,PDGFB,TFAP2E,EPCAM,RPS6KA2,HSF2,CTNNB1,GRHL1,NPNT,PSMC2,ELF5,PASK,MITF,ASH2L,ARNT2,MYBL1,ZNF462,THRB,PCGF5,TRIM8,CITED4,ASXL1,NFE2L1,EZR,EAF2,SEC14L2,MDK,KLF12,MAFF,PSMC1,NR2C2,RUNX2,PPP1R12A,ETV5,FBLN1,BMP2,RB1,DAZAP1,GATA2,PRKCI,EBF4,MDFIC,WNT3A,ELK3,RGMB,EGFR,ONECUT1,INSR,CSF1,PLPP3,NFKBIA,NLRC5,RARG,TOB1,RAD21,KLF7,PAX6,UPF3B,FOXM1,TP53,P2RX7,ERBB2,CCNL1,OSR2,LPIN3,SS18,LMO4,SMO,CDH3,TWIST1,ZBTB49,NOTCH3,EPB41L4B,NFKB2,F2R,DVL2,UPF3A,CTH,SIRT1,AKT1,TCEB2,SERTAD3,ERBB2IP,CD40,JADE1,HSF4,RBL1,STAT6,TLE1,IRF7,AKNA,GLIS3,ANXA3,PINK1,TAB3,ARHGEF11,SERPINB9,HMGN3,TGFBR1,GBX2,TOP2A,IRF2BPL,BMP7,TOX2,GTF2F2,TFAP2A,ACTA2,BRD7,TRIM21,H2AFY,IQGAP3,NFE2L3,HES1,RHOA,DCAF6,WNT10B,HMGN5,NR3C1,NR4A1,RGCC,PPARA,MAML2,RUNX3,MPV17L2,BCL10,E2F1,ARRB1,PKD2,ZMIZ1,SOX8,AHR |
| 2.743e-03 | -5.90 | KIM_WT1_TARGETS_8HR_DN | MSigDB lists | KIM_WT1_TARGETS_8HR_DN | 118 | 29 | 17758 | 2588 |
ELK4,CDKN1C,AGPS,ACBD3,MTL5,RET,SOD2,MTRF1L,SLC11A2,IL18,AURKB,SPTLC2,PGAP1,ULK2,ITGA2B,STK17A,CTGF,FAM64A,PLK2,CALD1,DACT1,SIVA1,FJX1,GTF2F2,NRG1,MANF,LSM14B,CITED2,F2RL1 |
| 2.744e-03 | -5.90 | ductolobular_carcinoma | COSMIC cancer mutations | ductolobular_carcinoma | 1676 | 283 | 17775 | 2585 |
FAM171B,HSPG2,GRIK2,TSC22D3,RET,SMARCAL1,PPFIBP2,GATA3,FAM102B,TRAPPC8,CNTROB,PAK6,CYP1A1,PRICKLE3,PIK3CA,TMEM37,WBP4,TFG,TIAM1,CPE,DSTN,KIF13A,TNS1,LOXL2,SPNS3,COL12A1,AHRR,PLCG1,TBX1,BMP1,MAPK13,PDPR,GAB1,NFKBIE,GGA1,PRKAA1,MTL5,NOTCH2,KIAA1161,RAVER2,RAC2,FRY,AIM1,RANBP1,MSH2,SORL1,PANX2,DGKG,PPP6R1,RIMS2,PRODH,HPS3,STAT4,AMER1,PTPRH,KDM3A,GNA11,DHX32,MMP15,MAGED2,FAAH,ITPR1,SLC4A3,AGBL5,FGD6,DYSF,HOOK1,SERPINB1,RPS6KA3,XDH,ADAMTS16,ARHGAP11A,PLA2G4A,TESK2,RNF182,FLT3,APC2,KTN1,CDS1,CD46,RCN1,MUC16,ACAP2,CDH1,DACT1,CNNM4,ACSL4,DLG3,SCN3A,SNX8,FZD4,CAPN6,SYNE2,SLC11A2,RAB38,CBL,B3GALNT2,GIGYF1,NFIX,IRS2,CCNB3,JAK1,SIPA1L1,TRIOBP,STAT1,KLF5,PRIMA1,SLC25A30,GEN1,NR3C2,PRKAR1A,FARP1,GPR180,PLD2,PKN1,DNAH3,KCNC4,SIX4,SCML1,DTX3L,ANK1,ADD3,IGSF9,OXCT1,PHF7,PTEN,TMEM62,SGK3,ATP8B1,CNOT6L,MSH6,SMC4,HCN3,AMOTL2,LONRF3,BCL9,TCFL5,PIK3R1,ZKSCAN2,MAMDC4,FGFR2,ABCB1,ARFGAP3,GRIN2D,SSNA1,CENPE,ETAA1,WDR91,NCAPG2,PHC1,AGRN,HEBP1,EPHA4,FHDC1,ARFGEF1,NDRG2,ABCD4,PLS3,MAGOHB,ARHGEF10L,NUP210,C7orf49,RABEP2,CTNNB1,CDKL5,IL6ST,MKRN3,DPYSL2,ANKFN1,TLN2,NEB,DDX59,RASGRP1,KCNIP3,ASXL1,ARFRP1,ROR1,IDH1,TYSND1,RHEB,EDNRA,TNS4,MAN2A2,TMEM164,PLEKHG6,MAP2,CTNND1,RAP1GAP,PRKAA2,ARAP3,SERPINE2,PPP1R12A,ZCCHC24,ETV5,ASL,SAMD9,CORO1B,MYO5C,ZNF432,RB1,DAZAP1,GATA2,ICAM5,FRAS1,PLCB2,ALS2CL,TESK1,PARD3B,FBXO8,KBTBD8,RNF113A,UNC45B,ANKRD29,EGFR,RHPN1,GNAS,TSC1,UTP14C,NFKBIA,NLRC5,ZDHHC7,SHROOM2,JAK3,SEMA3A,RARG,RAD21,LMO7,SORBS1,AVPI1,NF2,TP53,P2RX7,CYP26A1,SYTL2,SDF4,PER2,ATP6V0B,TACC2,EFR3A,KIF14,PLCG2,SMO,SCN2A,SULF2,SUSD3,CLCN3,AKT1,PTPRU,MAP3K6,DUOX1,DNAJC10,MAOA,LIFR,NDST3,ABCA1,FAM134B,GOLIM4,JKAMP,ERI2,SLC9A2,HMGXB4,CD109,FOXP2,ADORA1,MAGEE1,GALNS,TRIM3,SUN2,AMFR,TTC7A,COL7A1,AKAP3,BCAR1,DGKE,MAP1B,FUCA1,DHRS2,ARRB1,GLB1,ACADM,ZMIZ1,ARHGEF4,GOLGB1 |
| 2.744e-03 | -5.90 | breast-carcinoma-ductolobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductolobular_carcinoma | 1676 | 283 | 17775 | 2585 |
FAM171B,HSPG2,GRIK2,TSC22D3,RET,SMARCAL1,PPFIBP2,GATA3,FAM102B,TRAPPC8,CNTROB,PAK6,CYP1A1,PRICKLE3,PIK3CA,TMEM37,WBP4,TFG,TIAM1,CPE,DSTN,KIF13A,TNS1,LOXL2,SPNS3,COL12A1,AHRR,PLCG1,TBX1,BMP1,MAPK13,PDPR,GAB1,NFKBIE,GGA1,PRKAA1,MTL5,NOTCH2,KIAA1161,RAVER2,RAC2,FRY,AIM1,RANBP1,MSH2,SORL1,PANX2,DGKG,PPP6R1,RIMS2,PRODH,HPS3,STAT4,AMER1,PTPRH,KDM3A,GNA11,DHX32,MMP15,MAGED2,FAAH,ITPR1,SLC4A3,AGBL5,FGD6,DYSF,HOOK1,SERPINB1,RPS6KA3,XDH,ADAMTS16,ARHGAP11A,PLA2G4A,TESK2,RNF182,FLT3,APC2,KTN1,CDS1,CD46,RCN1,MUC16,ACAP2,CDH1,DACT1,CNNM4,ACSL4,DLG3,SCN3A,SNX8,FZD4,CAPN6,SYNE2,SLC11A2,RAB38,CBL,B3GALNT2,GIGYF1,NFIX,IRS2,CCNB3,JAK1,SIPA1L1,TRIOBP,STAT1,KLF5,PRIMA1,SLC25A30,GEN1,NR3C2,PRKAR1A,FARP1,GPR180,PLD2,PKN1,DNAH3,KCNC4,SIX4,SCML1,DTX3L,ANK1,ADD3,IGSF9,OXCT1,PHF7,PTEN,TMEM62,SGK3,ATP8B1,CNOT6L,MSH6,SMC4,HCN3,AMOTL2,LONRF3,BCL9,TCFL5,PIK3R1,ZKSCAN2,MAMDC4,FGFR2,ABCB1,ARFGAP3,GRIN2D,SSNA1,CENPE,ETAA1,WDR91,NCAPG2,PHC1,AGRN,HEBP1,EPHA4,FHDC1,ARFGEF1,NDRG2,ABCD4,PLS3,MAGOHB,ARHGEF10L,NUP210,C7orf49,RABEP2,CTNNB1,CDKL5,IL6ST,MKRN3,DPYSL2,ANKFN1,TLN2,NEB,DDX59,RASGRP1,KCNIP3,ASXL1,ARFRP1,ROR1,IDH1,TYSND1,RHEB,EDNRA,TNS4,MAN2A2,TMEM164,PLEKHG6,MAP2,CTNND1,RAP1GAP,PRKAA2,ARAP3,SERPINE2,PPP1R12A,ZCCHC24,ETV5,ASL,SAMD9,CORO1B,MYO5C,ZNF432,RB1,DAZAP1,GATA2,ICAM5,FRAS1,PLCB2,ALS2CL,TESK1,PARD3B,FBXO8,KBTBD8,RNF113A,UNC45B,ANKRD29,EGFR,RHPN1,GNAS,TSC1,UTP14C,NFKBIA,NLRC5,ZDHHC7,SHROOM2,JAK3,SEMA3A,RARG,RAD21,LMO7,SORBS1,AVPI1,NF2,TP53,P2RX7,CYP26A1,SYTL2,SDF4,PER2,ATP6V0B,TACC2,EFR3A,KIF14,PLCG2,SMO,SCN2A,SULF2,SUSD3,CLCN3,AKT1,PTPRU,MAP3K6,DUOX1,DNAJC10,MAOA,LIFR,NDST3,ABCA1,FAM134B,GOLIM4,JKAMP,ERI2,SLC9A2,HMGXB4,CD109,FOXP2,ADORA1,MAGEE1,GALNS,TRIM3,SUN2,AMFR,TTC7A,COL7A1,AKAP3,BCAR1,DGKE,MAP1B,FUCA1,DHRS2,ARRB1,GLB1,ACADM,ZMIZ1,ARHGEF4,GOLGB1 |
| 2.745e-03 | -5.90 | p53 signaling pathway | KEGG pathways | hsa04115 | 68 | 20 | 6908 | 1076 |
CCNE2,CASP3,DDB2,CD82,CASP9,TP53,CCNB1,SESN1,CDK1,TP53I3,FAS,TP73,CCND1,SESN3,CCNB3,PTEN,BAX,SERPINB5,STEAP3,CCNB2 |
| 2.745e-03 | -5.90 | p53 signaling pathway | KEGG pathways | ko04115 | 68 | 20 | 6908 | 1076 |
CCNE2,CASP3,DDB2,CD82,CASP9,TP53,CCNB1,SESN1,CDK1,TP53I3,FAS,TP73,CCND1,SESN3,CCNB3,PTEN,BAX,SERPINB5,STEAP3,CCNB2 |
| 2.751e-03 | -5.90 | CTCAGGG,MIR-125B,MIR-125A | MSigDB lists | CTCAGGG,MIR-125B,MIR-125A | 313 | 64 | 17758 | 2588 |
LFNG,RPS6KA1,FAM129B,KLC2,RET,FAM78A,TGOLN2,PLXNA1,SPTB,PHYHIP,ENTPD4,NUP210,KHNYN,PPME1,KCNS3,PPP1CA,LOXL1,FLOT2,MYT1,OLFML2A,KCNIP3,PTPN18,VPS4B,SERTAD3,GALNT7,ESYT1,ASB13,DAG1,ATP10D,ABR,NIN,MYLK,MADD,MAP3K11,EPB41L4A,STARD13,LIFR,CBX7,MAMDC2,BMF,SORT1,TBC1D1,PARP14,LRP4,FAM134A,ETS1,SGPL1,M6PR,CDK16,MEGF8,NECAB3,FAM134C,CORO2A,TEF,EIF5A2,SRRM3,PCTP,PTPRF,SLC4A4,SEMA4D,PELI2,SH3BP4,ALPK3,NIPA1 |
| 2.762e-03 | -5.89 | LU_AGING_BRAIN_DN | MSigDB lists | LU_AGING_BRAIN_DN | 150 | 35 | 17758 | 2588 |
CDH22,ATP8A1,CALB2,C5orf30,C6orf106,CALM3,TGOLN2,RAB6A,PARM1,RAD23A,CALM2,B3GALNT1,NAPG,GNB5,MEGF8,HSPA13,PDE4D,GAD1,TUBA4A,SMARCA2,RASGRF1,CALM1,RNF19B,RANBP9,CDK5R1,MAP1B,GABRD,ETS2,DNM1L,NR1D2,MAP2,PITPNA,ITPKA,CBX5,RPS6KA3 |
| 2.767e-03 | -5.89 | GCANCTGNY_V$MYOD_Q6 | MSigDB lists | GCANCTGNY_V$MYOD_Q6 | 863 | 155 | 17758 | 2588 |
DOC2A,EMX1,PPP4R4,ACVR1,PPM1J,HEBP1,CAMKK1,TSC22D3,PNPLA2,ARFGEF1,GATA3,MORF4L2,CAMK1D,PDGFB,SPTB,SLC9A7,CALM2,RGS12,STIM1,RGS3,LMAN2L,CABP1,SLC44A1,KCNS3,IQCD,NTN4,PPP1CA,KCNIP3,SNTB2,TFAP2C,PPP1R14C,SLC25A5,LHFPL2,RNF19B,COL12A1,ABR,MPRIP,RBM47,KLF12,WIPI1,ZNF367,EPB41L4A,NRGN,FRMD4A,CALM3,NDUFA4,RAB6A,TNFRSF19,PSIP1,SSX2IP,TFAP4,IGF1R,GATA2,FLRT3,KIF13B,NCAM1,ZRANB1,DPYSL5,PLEKHA6,SLC37A1,PARD3B,OXR1,CALM1,TCF7,CYFIP2,UNC45B,MMP15,PRKAG2,COQ10A,FA2H,ITGA7,PELI2,MPP2,AGBL5,NR4A2,EFNA1,MAP3K5,DRP2,EGLN1,DMPK,EHD1,CCNE2,REPS2,DDIT4L,HDAC11,MORC4,IRX4,TDRKH,GRK6,BAHD1,PRR7,SYTL2,RNF220,SH3BP1,LMO4,DACT1,ENPP5,CDKN1B,DAB2IP,RASGEF1A,MYT1,SULT2B1,CLCN3,IGSF8,ATP1B1,DUSP4,ITPR3,TMTC2,FYN,PTPRJ,PSMD3,OVOL1,NRG1,COBL,FBLIM1,IGFBP6,PKN1,BEX2,PPP2R3A,HDAC9,FOXP2,ANK1,FUT8,SLC44A2,TSPAN13,ERBB3,CITED2,GFI1,TPCN1,PVRL4,TGIF1,CASK,LONRF3,TACC1,PHLDB3,DENND1B,TEF,CRIP2,C1GALT1C1,PRICKLE1,COL7A1,FOS,ARHGAP24,SMTNL2,DGCR2,AMMECR1,SPINT2,E2F1,NR4A3,RYK,GRIN2D,OSR1,ZMIZ1,SHOX2,SNPH |
| 2.769e-03 | -5.89 | CD1B (CD1b molecule) | protein interactions | 910 | 49 | 16 | 16036 | 2547 |
CPD,ADAMTS2,PODXL2,GALNT12,MAN1A2,TNFSF9,QSOX2,HLA-A,ASPHD2,SLC27A6,IMPAD1,NETO2,LRP11,CHPT1,OCLN,FAM69A |
| 2.770e-03 | -5.89 | LEE_EARLY_T_LYMPHOCYTE_DN | MSigDB lists | LEE_EARLY_T_LYMPHOCYTE_DN | 53 | 16 | 17758 | 2588 |
KLF2,HLA-E,HLA-F,EMP3,IL27RA,DENND2D,HLA-A,STK17A,SCML1,HLA-B,LDLRAP1,PTPRJ,NLRC5,HLA-C,TBC1D4,TUBA4A |
| 2.770e-03 | -5.89 | REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | MSigDB lists | REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | 53 | 16 | 17758 | 2588 |
CCNE2,PSMB4,PSME2,PSMD7,PSMD10,CUL1,PSME1,PSMA4,CCNA2,PSMD1,PSMD3,PSMC2,CDKN1B,CKS1B,PSMC1,PSMA5 |
| 2.772e-03 | -5.89 | MHC_I | pfam domains | PF00129 | 18 | 8 | 16629 | 2504 |
HLA-B,MICB,HLA-E,HLA-F,RAET1L,HLA-C,ULBP2,HLA-A |
| 2.773e-03 | -5.89 | KLHL35 (kelch-like family member 35) | protein interactions | 283212 | 5 | 4 | 16036 | 2547 |
MX1,TGFBR1,ACVR1,APPBP2 |
| 2.773e-03 | -5.89 | SEMA3B (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B) | protein interactions | 7869 | 5 | 4 | 16036 | 2547 |
PAK6,SEMA3A,NRP2,SEMA3B |
| 2.773e-03 | -5.89 | TNS4 (tensin 4) | protein interactions | 84951 | 5 | 4 | 16036 | 2547 |
CASP3,ERBB3,CBL,EGFR |
| 2.773e-03 | -5.89 | TUBB (tubulin, beta class I) | protein interactions | 615087 | 5 | 4 | 16036 | 2547 |
DPYSL5,DPYSL4,DPYSL2,DPYSL3 |
| 2.773e-03 | -5.89 | Ubc (ubiquitin C) | protein interactions | 22190 | 5 | 4 | 16036 | 2547 |
DDX58,CDKN1B,SYK,EGFR |
| 2.773e-03 | -5.89 | VWA1 (von Willebrand factor A domain containing 1) | protein interactions | 64856 | 5 | 4 | 16036 | 2547 |
VWA1,RCN1,HSPG2,PDIA6 |
| 2.773e-03 | -5.89 | Espl1 (extra spindle pole bodies 1, separase) | protein interactions | 105988 | 5 | 4 | 16036 | 2547 |
CCNB1,CDK1,ESPL1,PTTG1 |
| 2.773e-03 | -5.89 | DERL3 (derlin 3) | protein interactions | 91319 | 5 | 4 | 16036 | 2547 |
MFI2,SERPINA1,AMFR,UBE2J1 |
| 2.777e-03 | -5.89 | MODULE_459 | MSigDB lists | MODULE_459 | 395 | 78 | 17758 | 2588 |
ACVR1,AASS,MRPS15,TP53,MAPK4,CCNL1,NANS,BAIAP3,CMTM6,C1orf116,CYP1A1,RNF220,METTL7A,PAQR5,ESPN,EPB41L4B,PDE4D,SCARA3,TUBA4A,ATG4D,TMCC2,TDP1,TCEB2,LAP3,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRIM7,KDM4D,AMZ2,PTGS2,PI4K2B,NEIL1,MPRIP,PLEKHG1,RNASEL,RRAGD,LMTK3,CDH22,FAM169A,SLC25A27,C6orf106,CTSZ,ISYNA1,IL18R1,C9orf69,CDK16,TMEM62,CITED2,FAIM,CNOT6L,ITM2C,EEF1D,MOB4,HMGN5,TBC1D8B,FMN1,ADCK3,MICB,PIP4K2C,FURIN,BCL2L13,FOS,BSDC1,FUCA1,CD8A,CSF1,WDR19,S100A5,FGD6,NXPH4,MAL2,GEM,TMEM120A,C17orf75,PKIA |
| 2.777e-03 | -5.89 | negative regulation of Wnt signaling pathway | biological process | GO:0030178 | 184 | 42 | 16441 | 2455 |
CTHRC1,PSME2,SOX9,LRP4,PSMD7,PSMD10,AES,PSME1,NOTUM,ZNRF3,APC2,HMGXB4,FZD6,PPP2R3A,CTNNBIP1,BMP2,CCND1,PSMD1,DACT1,PSMC2,TAX1BP3,DAB2IP,WNT3A,PSMA5,DVL2,MDFI,PSMB4,KREMEN2,AMER1,PRICKLE1,NPHP3,PSMA4,CXXC4,ANKRD6,PSMD3,NKD1,WWTR1,TBX18,TRABD2A,TLE1,CTNND1,PSMC1 |
| 2.788e-03 | -5.88 | interferon-gamma secretion | biological process | GO:0072643 | 8 | 5 | 16441 | 2455 |
BTN3A1,BTN3A2,GATA3,RNF19B,F2RL1 |
| 2.788e-03 | -5.88 | glial cell apoptotic process | biological process | GO:0034349 | 8 | 5 | 16441 | 2455 |
CASP3,RB1,CASP9,TP53,BAX |
| 2.788e-03 | -5.88 | cytoskeletal anchoring at nuclear membrane | biological process | GO:0090286 | 8 | 5 | 16441 | 2455 |
SUN1,SUN3,SUN2,SYNE3,SYNE2 |
| 2.790e-03 | -5.88 | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | 205 | 45 | 17758 | 2588 |
CTHRC1,SCN5A,SERPINE2,NUAK1,ZCCHC24,HEXB,UBE2Z,MRAS,SLC1A3,MICALL2,TMPRSS4,SYTL2,PDIA4,NOV,TIMP1,P4HB,BHLHE41,DRAM1,RPN2,TSPAN1,MOXD1,LOXL1,ITM2C,CKAP4,DLGAP1,SOAT1,PDGFC,TIMP2,USP31,PRICKLE1,ITPR3,ANTXR1,NFIX,SOCS3,TRIM47,PROM1,RPL12,PLK2,AXL,PGM2L1,OSMR,NFKBIZ,FHL1,PLOD3,OCLN |
| 2.799e-03 | -5.88 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma | 35 | 12 | 17775 | 2585 |
KIF5B,RB1,SS18,CTNNB1,CDH1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 2.804e-03 | -5.88 | dendritic spine | cellular component | GO:0043197 | 107 | 27 | 17570 | 2579 |
MOB4,P2RX4,FARP1,EPHA4,GRIN1,STRN4,FBXO2,PRKAR2B,SLC1A3,ARF4,GRM5,CDK5R1,MAP1B,ADORA1,GRID2IP,PTEN,ANKS1B,SIPA1L1,ARRB1,GPER1,CTTN,PPP1CA,ITPKA,RGS14,NRGN,LZTS1,DRD1 |
| 2.805e-03 | -5.88 | negative regulation of cellular protein localization | biological process | GO:1903828 | 131 | 32 | 16441 | 2455 |
LZTFL1,TXN,NFKBIE,THRA,RAB23,PSMD10,BCL2L1,BARD1,APC2,NOV,SP100,BMP7,CABP1,UBE2J1,TAX1BP3,DAB2IP,MDFIC,MAPK7,TMBIM1,MDFI,CHP1,BAG4,ERLEC1,DMTN,LITAF,TP53INP2,PPP2R5A,NFKBIA,WWTR1,PKD2,YOD1,PKIA |
| 2.810e-03 | -5.87 | fibrous_tissue_and_uncertain_origin | COSMIC cancer mutations | fibrous_tissue_and_uncertain_origin | 285 | 59 | 17775 | 2585 |
ATP9A,RET,TP53,ERBB2,CNTNAP2,NUCB2,FLT3,CARD10,ZFYVE9,SH3RF2,KIF5B,CDKN2C,RB1,SS18,ACAP2,CTNNB1,ITGB8,CDH1,PFKL,PTEN,FRYL,MSH2,SMO,PIK3CA,ABCA2,SORL1,C8orf58,TFG,PAQR7,ENPP4,KCNJ12,SGCE,ATL1,ERMP1,LCA5,AKT1,NR3C1,CASP9,PIK3R1,KIAA1109,IDH1,TXNDC11,BCAR1,GNA11,EGFR,PRX,GNAS,CDK5RAP1,TSC1,DNAJC10,INSR,CDK19,FGFR2,SLC2A6,NAB2,TRAF5,JAK3,LZTS1,PRKAR1A |
| 2.815e-03 | -5.87 | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP | 161 | 37 | 17758 | 2588 |
DEPDC1,CAST,SLC1A3,DOCK11,NTAN1,KTN1,B3GALNT1,PDCD10,PTEN,LHX6,ATRNL1,DIXDC1,KLF9,SEMA3G,SCYL3,ODF2L,EBAG9,GFPT1,ADAMTS2,SGCE,GCLC,RNF11,C1GALT1C1,SESN1,CASP4,EGFR,RHEB,ULK2,FAM177A1,TMEM30A,SLC35B3,P4HA2,FGF18,PIAS2,TLE1,NRGN,USP16 |
| 2.824e-03 | -5.87 | GSE3982_MAST_CELL_VS_BCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_BCELL_UP | 194 | 43 | 17758 | 2588 |
RMND5A,PCOLCE,SORBS1,CACNA2D2,FLOT1,CCDC68,HES2,REPS1,LMNA,SPP1,NOV,PSMD1,OSBPL3,PSMC2,PAPSS1,DRAM1,DAPK1,DUSP10,CTTN,SPRY2,DENND1B,CORO2A,PIK3R1,EIF5A2,SPA17,YES1,IDH1,PCTP,LEPR,FRMD4B,GABARAPL1,SOX13,IL1R1,DCTN6,FYN,SEC14L4,P4HA2,BMP1,PPM1H,ARRB1,KPNA2,ANXA9,RNF146 |
| 2.824e-03 | -5.87 | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | 194 | 43 | 17758 | 2588 |
CCNC,GALK1,CDS2,ARMCX3,UGP2,CAST,MCTP2,TMX4,HEXB,FTH1,PLD2,GPSM2,SGPL1,ITGA3,CTSC,TACC2,PPME1,TSPAN6,PAPSS1,TOX2,N4BP3,SGK1,TAX1BP3,TNFRSF12A,RCAN3,ALDH3A2,TLE6,RBMS2,B9D2,AMFR,SPATA13,FURIN,EAF2,FNDC3A,FRMD4B,CCDC6,PLOD2,TMEM30A,MADD,GEM,SERPINB1,FAM45A,FAM134B |
| 2.824e-03 | -5.87 | GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | 194 | 43 | 17758 | 2588 |
UNKL,BIN1,RMND5A,LTBP1,CDK17,DYRK3,UBASH3B,BACE1,CACNA2D2,GABRG2,PGAP1,KIAA1161,SPP1,MUC16,UBE2Q2,RNF128,MTMR10,SORL1,MYLIP,TMBIM1,WBP5,SYPL1,CDKN2AIP,ARFRP1,RAD17,HEATR5A,ANTXR1,STK17B,TRUB1,RANBP9,BTG1,LDLRAP1,RBM47,TWSG1,MATN2,UBE2D2,DTX4,PGRMC1,RHOBTB2,PIEZO1,APBA2,ARSB,TOB1 |
| 2.824e-03 | -5.87 | GSE30083_SP2_VS_SP3_THYMOCYTE_DN | MSigDB lists | GSE30083_SP2_VS_SP3_THYMOCYTE_DN | 194 | 43 | 17758 | 2588 |
CMAS,SORT1,KIAA1462,CERCAM,SELL,FAM78A,BAIAP3,MGAT5B,SEPT4,FAM101B,IL18R1,CDK14,E2F7,CEP97,CASC4,LMO4,KLF3,FBXL14,PLEKHF1,IL17RA,SGK1,IFIT1,NOTCH3,SYTL3,GM2A,S100A6,PRODH,CXXC5,PQLC3,CORO2A,PDE5A,IGSF8,TRIM9,PITX2,ALDH3B1,LDLRAP1,PPP2R5A,DCK,TBX18,UACA,SERPINI1,SYT13,F2RL1 |
| 2.824e-03 | -5.87 | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_DN | MSigDB lists | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_DN | 194 | 43 | 17758 | 2588 |
CASP3,CKAP2,SLC25A13,ITGA6,PDIA5,ABCG2,PSMD7,MORC4,NCKAP1,CA8,ERP29,FBLN1,BARD1,BEX2,ITGA2B,EPDR1,FAM111A,ARVCF,GOT1,BUB1,AK3,RAG1,F2R,SYTL3,CCDC88A,PGM1,MRPS33,CENPA,GCLC,DSTN,EZR,ERP44,PRKCQ,ANLN,NMT2,TXK,PTPRF,AMZ2,OTUD6B,RAP2C,AURKA,NUP37,AHR |
| 2.824e-03 | -5.87 | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | 194 | 43 | 17758 | 2588 |
TXN,TBC1D1,PNPLA2,TXNDC9,CHAC2,MORF4L2,DSE,APPBP2,CORO1B,CDS1,CA2,SNX18,FICD,XYLT2,PPP4R1,SLC30A6,SRP54,RFX5,MTMR11,CACNA1D,ALPK1,PIKFYVE,ARMCX6,TMEM68,PLSCR1,DENND1B,FOXJ2,ACBD3,RC3H2,NFE2L1,COX11,EZR,TNS4,LEMD2,ZNF628,TRAM2,FAM114A1,ITPR1,CABIN1,ZDBF2,KIF12,TTC39C,NRBP1 |
| 2.824e-03 | -5.87 | EPHA-mediated growth cone collapse | REACTOME pathways | R-HSA-3928663 | 34 | 12 | 8202 | 1235 |
EPHA10,MYL9,FYN,RHOA,EPHA4,EFNA5,EFNA1,EPHA1,MYH14,YES1,MYL12B,NGEF |
| 2.835e-03 | -5.87 | protein dimerization activity | molecular function | GO:0046983 | 1148 | 204 | 16491 | 2452 |
ACVR1,ADD1,EPAS1,GRIK2,TRIM5,CRYM,HEXB,TAP1,GATA3,TAF6L,SNX9,PDGFB,SLC8B1,ERP29,BARD1,SPTB,SLC9A7,TFAP2E,HSF2,NUP210,P4HB,IL6ST,CABP1,ALDH1A3,MITF,ARNT2,ANO4,PTPRE,S100A13,APOBEC3G,SMAGP,FGFR1OP2,RASGRP1,OLFML2A,SOD1,TRIM8,CENPA,ASCL5,CDA,BNIP3L,CR2,CCBL2,TFAP2C,PRKRA,IDH1,MYOM1,TP53I3,PLEKHB1,AHRR,TRIM9,ENPP1,HPSE,DNM1L,LIMK1,TBX1,PPP2R4,MAP3K11,ADIPOR1,GLA,RAP1GAP,E2F8,NR2C2,RRAGD,SOX9,ABCG2,PSMD7,HES2,ANO1,MECOM,TFAP4,BMP2,ITGA3,BHLHE41,FLRT3,EBF4,MSH2,MAP3K9,ZMYM1,CCDC88A,ANO6,PYGL,HMG20B,EIF2AK1,KIF20B,EGFR,NUDT16,NCOA3,PVRL2,DCK,CSF1,PRPS2,DGAT2,S100A5,NR4A2,ALG2,MAP3K5,CBX5,NRBP1,CTBP1,TMEM173,XDH,DRD1,S100A11,THRA,TP53,ABCG4,P2RX7,ERBB2,MAPK4,BCL2L1,FLT3,EXT2,MXD1,PDGFA,SP100,SRR,DAB2IP,TWIST1,ECE1,FLOT2,NAGA,NR2C1,SEPHS1,GCA,CLCN3,TAF5,RIPK2,FZD4,DRAP1,VPS4B,GTF2A2,H2AFV,EBF2,MYPOP,PTGS2,ALDH5A1,IDE,PAFAH1B3,STK26,BHLHB9,AXL,WWTR1,KIAA1804,STAT1,SLC27A1,SPTBN5,CHMP4B,ANXA9,PDXK,ARNT,LIFR,GCLM,BIK,LRP4,FLOT1,CAPN2,FOXP2,TOP2A,PDCD10,CARD8,OXCT1,IRAK1,ADORA1,MYCL,TFAP2A,BAX,H2AFY,HMGCL,ABCD1,MXD3,ERBB3,RAG1,NCOA2,S100A6,CAMK2G,MSH6,SMC4,P2RX4,PVRL4,HES1,PDGFC,SHMT1,FBLN5,GCLC,NR4A1,TCFL5,PIK3R1,GRIN1,NADK2,FAM109A,PRDX4,PITX2,CD8A,RAB11FIP2,FGFR2,DBI,TBX18,NR4A3,PKD2,SOX8,USF2,AHR,ACOT7,ABCG1 |
| 2.837e-03 | -5.86 | MODULE_220 | MSigDB lists | MODULE_220 | 325 | 66 | 17758 | 2588 |
UGT8,PAX6,EPAS1,EPHA4,ERBB2,NRG2,EMP2,TGFBR3,CTGF,ARTN,DPYSL2,CYP1B1,S100A4,UTRN,ARHGDIB,ROR1,CD40,LDB2,MYOM1,DPYSL3,MDK,HLF,TBX1,WFS1,BMP1,TLE1,EFNA5,NRG1,SERPINI1,NRGN,PPP2R5D,NKX3-1,EPS8,SOX9,APBA1,CRABP2,GSTP1,EFNB1,HOXB2,ELF3,NEO1,RND1,ADORA1,CALD1,TFAP2A,ARVCF,ACTA2,ALDH3A2,POU6F1,WNT10B,MYBL2,EMP3,COL7A1,AKAP3,DPYSL4,LEPR,CD8A,SEMA4D,CSF1,NAB2,FHL1,DRP2,SEMA3A,RARG,L1CAM,CSRP2 |
| 2.840e-03 | -5.86 | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | MSigDB lists | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | 172 | 39 | 17758 | 2588 |
FARP1,LMTK3,P2RX7,CALM3,CCNL1,COMMD5,APBA1,C11orf95,CALM2,MARCH8,CTSC,CAPG,DAPK1,BRI3,CNPY3,ORAI2,TAF5,ZC3H11A,FMN1,CALM1,PYGL,C12orf65,ERBB2IP,ZFAND5,NPDC1,COL12A1,CNOT2,PEX5,KCNMB4,HPSE,SEMA4D,APPL2,NOD2,FAM117A,CTSA,PLXND1,DEF6,RNF146,NR2C2 |
| 2.841e-03 | -5.86 | immune response-activating cell surface receptor signaling pathway | biological process | GO:0002429 | 278 | 59 | 16441 | 2455 |
THEMIS2,TAB3,INPP5D,PSME2,PSMD7,CALM3,BTN3A1,GATA3,CUL1,PSMD10,PSME1,PLD2,TEC,ITPR2,NCKAP1,PRKACA,CACNB4,CALM2,VASP,PSMD1,ELMO2,PTEN,PSMC2,PLCG2,PAK2,PIK3CA,BAX,PIK3CD,PDE4D,MAP3K7,NFKB2,SYK,PSMA5,RIPK2,PSMB4,MICB,CALM1,PIK3R1,CR2,PRKCQ,YES1,CYFIP2,ITPR3,BCAR1,PSMA4,TXK,BCL10,GPLD1,PLCG1,PTPRJ,FYN,LIMK1,PSMD3,NFKBIA,ITPR1,UBE2D2,NR4A3,ARPC2,PSMC1 |
| 2.842e-03 | -5.86 | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN | MSigDB lists | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN | 183 | 41 | 17758 | 2588 |
ARHGAP11A,PAPSS2,SLC16A14,FBXO2,RACGAP1,STIL,SSX2IP,FZD6,NRP2,TOP2A,ANK1,CYR61,PAQR5,NEK2,KIF22,KNTC1,WBP4,ETV4,OLFML2A,FADS2,MLEC,CEP89,CDC20,LITAF,CBX6,CCBL2,LOXL2,KIF11,PRIM1,TIMP3,PRRT4,CDCA5,DBI,MAOA,CLMN,CTNND1,NCAPG2,ESPL1,E2F8,SRSF9,DMPK |
| 2.842e-03 | -5.86 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | 183 | 41 | 17758 | 2588 |
SCN5A,TBC1D1,RASA2,CNTNAP2,PHLPP1,TRIB2,PHF1,APLP2,RNF220,FAM46A,CNTRL,PAIP2B,CD22,GALNS,FCHO1,TPST1,BCL6,POLL,SORL1,ZNF692,RAB20,FLOT2,MMD,KIAA0040,DCHS1,CD40,SESN1,SPTLC2,ATP10D,TCN2,KDM4D,PLCG1,MPRIP,AGPAT2,HTT,MMP17,DTX4,PIK3C2B,TTC9,ICOSLG,PHC1 |
| 2.842e-03 | -5.86 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 183 | 41 | 17758 | 2588 |
SLC35D2,ARHGEF3,NDRG1,HABP4,CACNA2D2,BTN3A1,IL27RA,TGOLN2,DENND2D,PHF1,EPS8L2,GBX2,TIMP1,PASK,COL6A1,KLF3,FXYD5,RCAN3,CITED2,MYLIP,ALDH3A2,NCOA2,TMBIM1,S100A6,CKAP4,CD55,KREMEN2,PQLC3,OSTM1,PIP4K2C,MYOM1,ULK2,FUCA1,PPP2R5A,DGCR2,JAK1,RIN3,MAPK13,PDXK,KLF7,FAM134B |
| 2.842e-03 | -5.86 | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 183 | 41 | 17758 | 2588 |
ARHGAP11A,CCNE2,GALK1,PCOLCE,PLEKHJ1,CPT2,CENPI,ERCC6L,BARD1,STIL,CCNA2,STIM1,CAPG,ZDHHC13,MDFIC,ETHE1,MPHOSPH9,MYO5A,CKS2,SPATA20,DDB2,FBXL16,MAPKAPK3,S100A4,ANO6,CAPNS1,RNF113A,NPC2,CCNF,PRDX4,PRDX3,ANKRD6,SPINT2,KIAA1804,AURKA,GLB1,ZMIZ1,CBX5,ANXA11,ACOT7,NXT2 |
| 2.845e-03 | -5.86 | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | 222 | 48 | 17758 | 2588 |
FRMD4A,CPEB4,IQGAP1,UBASH3B,ITGA6,EPHA4,SLC7A2,BCL2L1,PHLDA1,BMP2,RAC2,CA2,IL6ST,TNFRSF12A,PDE4D,TMEM8A,LMAN1,NFKB2,ULBP2,SYTL3,PPIF,DOCK4,PCGF5,CD55,ELK3,RAB3B,MFI2,PLAUR,PPARA,DNAJB14,LDB2,EGFR,PGF,KDSR,SERPINA1,UEVLD,OSMR,MAOA,CANT1,OTUB2,NFKBIZ,HMGA1,GEM,ITPKA,ST3GAL1,MAFF,ESYT2,RRAGD |
| 2.845e-03 | -5.86 | NUCLEOTIDE_BINDING | MSigDB lists | NUCLEOTIDE_BINDING | 222 | 48 | 17758 | 2588 |
GALK1,TNK1,DYRK3,ACVR1,PINK1,PEX6,TP53,ABCG2,TGFBR1,TRIB2,AIFM2,DHRS3,ABCD4,DAPK2,RALB,CDKL5,DAPK1,ABCA2,MSH2,PRKCI,PIM1,MSH6,SMC4,ABCC1,SEPHS1,MX1,MARK1,GCLC,SEPT6,PIF1,NUBP1,MAP3K6,STK17B,RHOB,RHEB,DGKE,STK17A,RND3,ACVRL1,ATP7B,STK38,PPP2R4,ABCB1,GEM,MAP3K5,ARF6,ABCG1,DMPK |
| 2.845e-03 | -5.86 | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | MSigDB lists | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | 222 | 48 | 17758 | 2588 |
KLF2,ADD1,CENPI,ARL4C,SOD2,ABCG2,EGR3,PHLDA1,SPSB1,ICAM1,H1FX,IER3,CALR,NOV,BTG3,PQLC2,ZFP36,FOSB,TFAP2A,SGK1,KLF9,GAD1,SLC12A2,TIPARP,SPRY2,EEF1D,CYP1B1,DUSP1,GCLC,PTGER4,SPA17,PRRC1,FOS,CDK5R1,FZD7,CD83,PTGS2,ETS2,AREG,PLK2,NFKBIA,RAB11FIP1,FAM117A,NR4A2,PIK3C2B,HOOK1,MAFF,EHD1 |
| 2.850e-03 | -5.86 | DORSAM_HOXA9_TARGETS_UP | MSigDB lists | DORSAM_HOXA9_TARGETS_UP | 35 | 12 | 17758 | 2588 |
ARHGAP11A,MAN2A2,INPPL1,ADD3,ST13,ETS2,RAB31,SERINC2,DHX8,PIM1,YES1,CTH |
| 2.850e-03 | -5.86 | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | MSigDB lists | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | 35 | 12 | 17758 | 2588 |
ITGA3,SERPINE2,GPRC5B,SOD2,FTH1,SOX8,DNER,CPE,RTN3,TSPAN7,HLA-A,PLEKHB1 |
| 2.850e-03 | -5.86 | MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | 35 | 12 | 17758 | 2588 |
SUN2,MID1IP1,CENPJ,UXT,TUBGCP6,PRC1,TUBG1,KIF23,NUSAP1,KIF2C,KIF11,CKAP5 |
| 2.850e-03 | -5.86 | ISOMERASE_ACTIVITY | MSigDB lists | ISOMERASE_ACTIVITY | 35 | 12 | 17758 | 2588 |
TOP2A,PGM1,GNPDA1,P4HB,GNE,PDIA5,PDIA3,ERP44,DSE,PDIA6,ERP29,GLCE |
| 2.857e-03 | -5.86 | mitotic spindle organization | biological process | GO:0007052 | 66 | 19 | 16441 | 2455 |
SUN2,RHOA,SPC25,NDC80,XIAP,MYBL2,KIF23,RACGAP1,AURKB,STIL,KIF11,DCTN6,PLK2,TUBGCP6,PPP2R4,NEK2,PRC1,AURKA,WDR62 |
| 2.864e-03 | -5.86 | small molecule catabolic process | biological process | GO:0044282 | 329 | 68 | 16441 | 2455 |
AASS,CRYM,CPT2,MCCC1,LPIN3,OAT,ECI1,CYP39A1,CYP26A1,EPM2A,INPP5E,CYP1A1,CYP4F11,FUT1,GOT1,ACOX2,ETHE1,CTH,PFKFB2,CCBL2,PNKD,CYP4F3,ALDH3B1,ALDH5A1,ACAD10,ABHD12,PEX2,PPP2R5D,GALK1,ALDH6A1,ENO2,GCAT,HAL,ASL,OXCT1,FUT2,PTEN,PFKL,FUT8,BDH1,PCYOX1,ECI2,ABCD1,AHCY,HMGCL,ALDH7A1,ACAD8,GAD1,MCCC2,FAH,CYP26B1,PRODH,PGM1,PCCB,SHMT1,ALDH2,PKM,AMDHD1,DHDH,DDAH1,NUDT16,ACADSB,FAAH,PLA2G15,PGM2L1,GLB1,ACADM,ACOT7 |
| 2.866e-03 | -5.85 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | 268 | 56 | 17775 | 2585 |
CPEB4,SHPRH,SUZ12,TP53,GATA3,SAMD9,ITPR2,NOTCH2,PHLPP1,FLT3,ETS1,TNFSF9,SLC9A2,CCND1,BTG3,RB1,MUC16,IRAK1,TACC2,PTEN,GATA2,FABP6,PLCG2,BCL6,SGK1,BRD7,CD70,NOTCH3,PIM1,NFKB2,SYK,HP1BP3,SMARCA2,PDGFC,RHOA,CELSR2,ASXL1,TACC1,NR3C1,BCL9,PIK3R1,UBE2A,KIF20B,IDH1,FAS,BCL10,GNAS,BTG1,PLCG1,JAK1,STAT6,TMEM30A,NFKBIA,JAK3,CBX5,RAD21 |
| 2.869e-03 | -5.85 | neural crest cell migration | biological process | GO:0001755 | 52 | 16 | 16441 | 2455 |
SEMA6B,ACVR1,RET,EFNB1,FGF19,GBX2,PITX2,SEMA4D,CORO1C,TBX1,SMO,TWIST1,SEMA3G,SOX8,SEMA3A,SEMA3B |
| 2.891e-03 | -5.85 | T cell mediated immunity | biological process | GO:0002456 | 26 | 10 | 16441 | 2455 |
CD46,CD8A,CD55,CTSC,MICB,DLG1,GATA3,BTN3A2,EMP2,ICAM1 |
| 2.891e-03 | -5.85 | lung epithelial cell differentiation | biological process | GO:0060487 | 26 | 10 | 16441 | 2455 |
THRB,KLF2,GRHL2,THRA,SOX9,GPSM2,SAV1,LTA4H,NFIB,FOXA1 |
| 2.892e-03 | -5.85 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | 145 | 34 | 17758 | 2588 |
CDKN1C,HLA-E,TSC22D3,FXYD3,SOD2,PSME1,F11R,SEPP1,TGFBR3,CA2,CDH1,PTEN,CALD1,CD9,BCL6,DAPK1,TACSTD2,CTSD,CITED2,SEMA3B,IFITM3,SAT1,NFE2L1,BNIP3L,IL1R1,BTG1,NFKBIA,MAOA,PIK3C2B,EFNA1,GEM,MAP3K5,CCNB2,CYBRD1 |
| 2.892e-03 | -5.85 | central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour | 217 | 47 | 17775 | 2585 |
NCKAP5,NF2,ESRP1,MAN1A2,SHPRH,RET,TP53,ERBB2,ZNF28,CNTNAP2,NOTCH2,FLT3,VPS26A,RB1,DOPEY2,ADD3,CTNNB1,CDH1,PTEN,GATA2,MSH2,SMO,PIK3CA,LIMCH1,RCAN3,PLCB2,MSH6,CELSR2,AKT1,SYNE2,PIK3R1,DCHS1,ATP8B3,AKAP3,IDH1,CASP4,EGFR,GNAS,SEC14L4,FGFR2,LIMK1,TBX1,SH3BP4,ITGAV,APBA2,JAK3,COL16A1 |
| 2.892e-03 | -5.85 | atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | atypical_teratoid-rhabdoid_tumour | 217 | 47 | 17775 | 2585 |
NCKAP5,NF2,MAN1A2,SHPRH,ESRP1,RET,TP53,ZNF28,ERBB2,NOTCH2,CNTNAP2,FLT3,VPS26A,RB1,DOPEY2,ADD3,CDH1,CTNNB1,PTEN,GATA2,MSH2,PIK3CA,SMO,LIMCH1,RCAN3,PLCB2,MSH6,CELSR2,AKT1,PIK3R1,DCHS1,SYNE2,ATP8B3,AKAP3,IDH1,CASP4,EGFR,GNAS,SEC14L4,FGFR2,TBX1,LIMK1,SH3BP4,ITGAV,JAK3,APBA2,COL16A1 |
| 2.897e-03 | -5.84 | PTB | pfam domains | PF08416 | 8 | 5 | 16629 | 2504 |
TNS4,TNS3,TNS1,EPS8,EPS8L2 |
| 2.901e-03 | -5.84 | regulation of reactive oxygen species metabolic process | biological process | GO:2000377 | 147 | 35 | 16441 | 2455 |
PINK1,FOXM1,TP53,HDAC6,PDGFB,GSTP1,ICAM1,IER3,RAC2,NOXA1,BMP7,DNM2,TFAP2A,MAP3K7,SYK,CYP1B1,P2RX4,CLCN3,SOD1,RHOA,FBLN5,AKT1,PDK3,ARF4,PLIN5,EGFR,STK17A,PTGS2,DDAH1,INSR,PRCP,PKD2,GLA,F2RL1,XDH |
| 2.908e-03 | -5.84 | Signaling by NOTCH | REACTOME pathways | R-HSA-157118 | 110 | 28 | 8202 | 1235 |
CCNC,HES1,ADAM17,TNRC6C,LFNG,ITCH,HDAC11,TP53,FURIN,CUL1,AGO4,MAML2,JAG2,RAB6A,NOTCH2,NEURL1B,HDAC6,DNER,HDAC9,CCND1,MDK,E2F1,DTX4,ARRB1,TLE1,HDAC1,NOTCH3,TMED2 |
| 2.915e-03 | -5.84 | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP | MSigDB lists | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP | 108 | 27 | 17758 | 2588 |
PLA2G4A,ELK3,RUNX2,IL15RA,BACE1,SEPT6,FURIN,SMARCAL1,PDGFB,TSPAN7,ZYX,PTGS2,SPP1,BFSP1,CTGF,CYR61,MAP2,ATP13A3,CAPG,BMP1,FXYD5,SGK1,CD70,CD81,CPE,AHR,DUSP1 |
| 2.917e-03 | -5.84 | SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | MSigDB lists | SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | 44 | 14 | 17758 | 2588 |
ING1,CTGF,HPSE,CDKN1C,AREG,DHRS2,CGREF1,BIK,ABCB1,GDF15,SERPINI1,NOTCH3,ULBP2,PHC1 |
| 2.917e-03 | -5.84 | TAGGTCA,MIR-192,MIR-215 | MSigDB lists | TAGGTCA,MIR-192,MIR-215 | 44 | 14 | 17758 | 2588 |
CTNNBIP1,RB1,DYRK3,GRHL1,TMTC3,WDR44,C1orf21,ARFGEF1,PCDH19,C6orf106,TCF7,BLCAP,CBL,ALCAM |
| 2.919e-03 | -5.84 | Ca2+ pathway | REACTOME pathways | R-HSA-4086398 | 61 | 18 | 8202 | 1235 |
TNRC6C,FZD4,CALM1,CALM3,AGO4,TCF7,ITPR2,ITPR3,GNB2,FZD6,CALM2,GNB5,CTNNB1,ITPR1,PRKG1,MAP3K7,FZD5,PLCB2 |
| 2.926e-03 | -5.83 | MAVS (mitochondrial antiviral signaling protein) | protein interactions | 57506 | 58 | 18 | 16036 | 2547 |
DDX58,KCNIP3,RIPK2,TRAF2,AMFR,ITCH,IFIT3,TSPAN6,STAT1,OTUB2,IRF7,OAS3,MAP3K7,TRAF5,NDFIP1,IFIH1,FLOT2,TMEM173 |
| 2.926e-03 | -5.83 | response to topologically incorrect protein | biological process | GO:0035966 | 163 | 38 | 16441 | 2455 |
FAF2,HSP90B1,ADD1,SEC61G,DNAJB2,JKAMP,DNAJC3,PDIA5,DNAJB11,FBXO6,HDAC6,DNAJB9,LMNA,CCND1,CALR,BAX,TMBIM6,DAB2IP,STT3B,MANF,MYDGF,PDIA6,HSPA2,CTDSP2,CTH,GFPT1,UFD1L,SEC61B,AMFR,ERO1A,KDELR3,ERP44,F12,VCP,WIPI1,WFS1,YOD1,HSPB1 |
| 2.929e-03 | -5.83 | SH2 | interpro domains | IPR000980 | 113 | 28 | 18293 | 2672 |
INPPL1,INPP5D,STAT4,PIK3R1,TNS1,TEC,YES1,CBL,RASA1,SH2D4A,SOCS3,TXK,BCAR3,TNS4,PLCG1,TNS3,FYN,JAK1,SHC3,RINL,STAT6,SH2D3C,RIN3,PLCG2,STAT1,JAK3,SYK,SOCS5 |
| 2.930e-03 | -5.83 | Joubert syndrome | SMPDB pathways | SMP00582 | 21 | 10 | 978 | 190 |
INPP5E,PTEN,INPP5D,PIK3R1,INPP4B,PIK3CA,ERBB2,PIK3CD,CDIPT,PIKFYVE |
| 2.930e-03 | -5.83 | Phosphatidylinositol Phosphate Metabolism | SMPDB pathways | SMP00463 | 21 | 10 | 978 | 190 |
INPP5E,PTEN,INPP5D,PIK3R1,INPP4B,PIK3CA,ERBB2,PIK3CD,CDIPT,PIKFYVE |
| 2.954e-03 | -5.82 | stem cell differentiation | biological process | GO:0048863 | 190 | 43 | 16441 | 2455 |
SEMA6B,ACVR1,RUNX2,RET,SOX9,TGFBR1,FAM101B,FGF19,EFNB1,GBX2,BMP2,EPCAM,TGFBR3,CTNNB1,BMP7,SMO,ADAM15,TWIST1,ERCC2,C10orf54,SEMA3G,ETV4,SEMA3B,EPB41L5,HES1,S100A4,AMER1,LOXL2,EDNRA,PITX2,SEMA4D,FGFR2,CORO1C,TBX1,WWTR1,STAT1,FAM83D,NRG1,EFNA1,SOX8,OSR1,SEMA3A,JARID2 |
| 2.972e-03 | -5.82 | cellular response to type I interferon | biological process | GO:0071357 | 71 | 20 | 16441 | 2455 |
MX1,IFITM3,HLA-E,USP18,HLA-F,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,SP100,STAT1,IRF2,IRF7,RNASEL,HLA-C,OAS3,IFIT1,IFI6,IRF1 |
| 2.972e-03 | -5.82 | type I interferon signaling pathway | biological process | GO:0060337 | 71 | 20 | 16441 | 2455 |
MX1,IFITM3,HLA-E,USP18,HLA-F,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,SP100,STAT1,IRF2,IRF7,HLA-C,IFIT1,OAS3,RNASEL,IFI6,IRF1 |
| 2.979e-03 | -5.82 | FCERI mediated Ca+2 mobilization | REACTOME pathways | R-HSA-2871809 | 30 | 11 | 8202 | 1235 |
CALM2,PLCG1,PLCG2,ITPR1,CALM1,CALM3,ITPR2,TEC,ITPR3,SYK,TXK |
| 2.982e-03 | -5.82 | mitotic spindle | cellular component | GO:0072686 | 53 | 16 | 17570 | 2579 |
ASPM,KIF23,RACGAP1,KIF20B,NUSAP1,CDK1,FAM83D,CAPG,AGBL5,AURKA,PKD2,KIF22,CENPE,CTTN,GEM,ESPL1 |
| 2.984e-03 | -5.81 | GSE17721_LPS_VS_POLYIC_12H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_12H_BMDM_DN | 189 | 42 | 17758 | 2588 |
LASP1,TM2D2,IL15RA,NDC80,CCNL1,GPSM2,MGST2,SDC1,ARHGEF40,LMNA,WEE1,DOPEY2,DNPEP,RABEP2,RGS3,CD9,TFG,DLG3,ODF2L,NAGA,SUN2,RASGRF1,TIMP2,SHARPIN,SAT1,CDYL,PLEKHO1,PSMA4,NFIB,STX3,LRRC42,UAP1,GPRC5B,PRCP,NAT1,ITPR1,ARF6,SERPINB1,RARG,E2F8,ANXA11,IRF1 |
| 2.984e-03 | -5.81 | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_DN | 189 | 42 | 17758 | 2588 |
CCNI,TCF25,TRIP10,PPM1J,THRA,PNPLA2,RASSF7,GPR180,TAF6L,CDIPT,NRP2,SAC3D1,UBE2Q2,ITGA3,RPN2,CTSD,TRAM1,KDELR1,GCNT1,CYP1B1,SYPL1,ING1,PFKFB2,TTC7A,CCDC34,ARHGDIB,PRRC1,FXR2,SNAPC2,BCAR1,GNA11,XKRX,IL1R1,AHRR,ATXN7L3,ITGA7,PIAS2,GLA,GEM,REEP4,MIIP,WDR63 |
| 2.984e-03 | -5.81 | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_DN | 189 | 42 | 17758 | 2588 |
GRN,LASP1,HECA,BMF,TSC22D3,CNOT8,FAM134A,SMARCAL1,GTF3A,DPP8,PCBP1,ZNF432,CXCL16,RALB,FBXO7,DUSP10,PPP1CA,NAGA,CTDSP2,FAM134C,ACBD5,ORAI2,TAF5,BAG4,PLEKHO1,UBAC1,TNFAIP8L1,CBL,CMTM7,DDX23,GDE1,ATXN7L3,SLC9A6,ARAP1,CCDC69,ZDHHC7,EIF4EBP2,PLIN3,SLC31A2,NRBP1,SRSF9,CTDSP1 |
| 2.984e-03 | -5.81 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 189 | 42 | 17758 | 2588 |
CASP3,TMEM184B,LGALS3,IBTK,ETNK1,CALM3,CHPF,GNS,RCN1,CALM2,SS18,C7orf49,IMPAD1,BHLHE41,FUT8,RRBP1,GOT1,TFG,FAM69A,NEK4,GFPT1,PCCB,TIMP2,MLEC,LAP3,CALM1,C1GALT1C1,FNDC3A,PDHX,LRRC42,MAGED2,RBM47,SLC25A4,DNM1L,WIPI1,RCBTB2,WFS1,ERAP1,AURKA,ARFGAP3,ADIPOR1,ATP6V1C1 |
| 2.987e-03 | -5.81 | CCNA2 (cyclin A2) | protein interactions | 890 | 95 | 26 | 16036 | 2547 |
CDKN1C,CALM1,CDC20,TP53,MYBL2,CUL1,HERC5,PKMYT1,NTAN1,CDC25C,CDK1,RAD23A,TP73,RB1,BTG1,PCNA,CCNA2,CTNNB1,RBL1,TRAF3IP1,E2F1,PRC1,CDKN1B,CKS1B,TBC1D4,CKS2 |
| 2.987e-03 | -5.81 | SLC39A4 (solute carrier family 39 (zinc transporter), member 4) | protein interactions | 55630 | 95 | 26 | 16036 | 2547 |
GOLIM4,MPZL1,TMEM43,ATP9A,MRS2,KDELR3,POMGNT1,EFNB1,C3orf33,ATP13A2,MAN2A2,LEMD2,DHRS13,ABHD12,MGAT1,FUT8,SLC46A1,TMEM143,ABCD1,GLB1L2,STEAP3,TMEM120A,FAR2,C1orf43,MGAT5,CKAP4 |
| 2.990e-03 | -5.81 | GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | 167 | 38 | 17758 | 2588 |
DYRK3,ELOVL7,SDC4,SOD2,IL18,CD274,SLC1A3,DNER,ICAM1,IER3,ZFX,BTG3,E2F7,ITGB8,ZFP36,DRAM1,SNX10,RPGR,MSH6,RIPK2,RAPGEF2,PLAUR,SLC11A2,PIM3,SAV1,RNF19B,CDK1,CD83,SOCS3,PTGS2,ETS2,MFSD2A,NFKBIA,RAP2C,SLC2A6,NFKBIZ,NIPA1,EHD1 |
| 2.990e-03 | -5.81 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP | 167 | 38 | 17758 | 2588 |
EXPH5,AGRN,SERPINE2,KLHL13,TMEM41B,ITGA6,RHPN2,TMEM170B,NUCB2,NUDT12,PIGL,DDR1,SNX9,SCML1,CYHR1,HSF2,IGF1R,CADPS2,PIK3CD,BTBD3,KCTD3,CD55,TIMP2,MPP1,BNIP3L,SLC11A2,MEST,STK17A,SERTAD2,GPRC5B,RIN3,EFNA1,CEP41,APBA2,NDFIP1,SNPH,PCSK5,FAM134B |
| 2.990e-03 | -5.81 | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP | 167 | 38 | 17758 | 2588 |
SUN1,ELK4,PRKAA2,UNKL,KLF2,CHCHD7,FAM199X,DNAJC3,ITGA6,EPHA4,PLXNA1,PHF1,ABCD4,SCML1,TMEM63A,IGF1R,MGAT4A,FAM13B,FAM63A,SORL1,ZMYM1,ALS2CL,EBAG9,POU6F1,MBNL3,SLC44A3,PGF,TSC1,HS6ST1,RCBTB2,SEC14L4,STK38,WDR19,APBA2,NDFIP1,ZNF502,NR3C2,CBX7 |
| 2.996e-03 | -5.81 | meninges-meningioma-transitional | COSMIC cancer mutations | meninges-meningioma-transitional | 15 | 7 | 17775 | 2585 |
CDKN2C,NF2,AKT1,PTEN,EGFR,SMO,PIK3CA |
| 2.996e-03 | -5.81 | soft_tissue-blood_vessel-haemangioendothelioma-epithelioid | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioendothelioma-epithelioid | 15 | 7 | 17775 | 2585 |
TSC1,PLCG1,CTNNB1,AKT1,IDH1,PTEN,PIK3CA |
| 2.996e-03 | -5.81 | meninges-meningioma-fibroblastic | COSMIC cancer mutations | meninges-meningioma-fibroblastic | 15 | 7 | 17775 | 2585 |
CDKN2C,NF2,AKT1,PTEN,EGFR,SMO,PIK3CA |
| 2.996e-03 | -5.81 | salivary_gland-parotid-carcinoma-acinic_cell_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-acinic_cell_carcinoma | 15 | 7 | 17775 | 2585 |
SAMD8,KIAA1109,LRRC1,APBA1,CCDC74A,TP53,SLC25A36 |
| 2.996e-03 | -5.81 | transitional | COSMIC cancer mutations | transitional | 15 | 7 | 17775 | 2585 |
CDKN2C,NF2,AKT1,PTEN,EGFR,SMO,PIK3CA |
| 2.996e-03 | -5.81 | haemangioendothelioma | COSMIC cancer mutations | haemangioendothelioma | 15 | 7 | 17775 | 2585 |
TSC1,PLCG1,CTNNB1,AKT1,IDH1,PTEN,PIK3CA |
| 2.996e-03 | -5.81 | central_nervous_system-brain-other-ganglioglioma | COSMIC cancer mutations | central_nervous_system-brain-other-ganglioglioma | 15 | 7 | 17775 | 2585 |
TSC1,CTNNB1,AKT1,IDH1,PTEN,EGFR,PIK3CA |
| 2.998e-03 | -5.81 | HOXA9_DN.V1_DN | MSigDB lists | HOXA9_DN.V1_DN | 178 | 40 | 17758 | 2588 |
ARHGAP11A,COL9A3,ZNF395,TSC22D3,EPS8,GMCL1,SLC7A2,TRMT2B,NOTCH2,PHLPP1,PSIP1,FZD6,FANCI,H1FX,PER2,APOBEC3B,RB1,SPP1,KCTD15,ALDH1A3,PLK4,IGFBP2,RNASEH2A,LMAN1,SPRY2,SMAGP,FADS2,SHMT1,HMGN5,MICB,CXorf57,KCTD20,SAV1,GINS4,ALDH5A1,PTER,HOXA9,ARRB1,NRGN,E2F8 |
| 2.998e-03 | -5.81 | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 178 | 40 | 17758 | 2588 |
CD99,FOXM1,MRPS15,GNPDA1,CTDSPL,CCNB1,CD109,CPNE2,MGAT1,KCNK5,KCNN4,BDH1,CAPG,CD9,HMGCL,RNASEH2A,AK3,HEXIM2,PXMP4,ETHE1,PSMA5,MSH6,SHMT1,SLC39A8,WHSC1,GLO1,ILK,XRCC6BP1,POLD3,IDH1,ALCAM,DHX32,AHRR,AGPAT2,PAFAH1B3,FAM64A,PRDX3,HMGA1,TMEM120A,CSRP2 |
| 2.998e-03 | -5.81 | GSE22886_NAIVE_CD4_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_DC_UP | 178 | 40 | 17758 | 2588 |
SIGIRR,FAM169A,ADD1,TSC22D3,GATA3,CBLL1,ETS1,LTBP3,RSAD1,PASK,KLF9,EPHB4,PDE4D,ITM2C,MYLIP,CAMK2G,DUSP1,CASK,UXT,SYNE2,BTN3A2,TCF7,CYFIP2,STK17B,PLEKHB1,TXK,BTG1,KLF12,WDR19,INPP4B,FAM117A,NR4A2,SLC25A38,HOOK1,TBC1D4,PKIA,SNPH,EHD1,DOCK9,FAM134B |
| 2.998e-03 | -5.81 | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN | 178 | 40 | 17758 | 2588 |
COL9A3,ADD1,ARHGEF7,ADO,RASGRP3,IL13RA1,BMP2K,PARM1,CDK14,CA2,IRAK1,METTL7A,TMEM62,KCNN4,BHLHE41,PLCG2,PAPSS1,OPN3,UBE2J1,TSPAN13,SYK,GM2A,CKAP4,SCN3A,SYPL1,ING1,ALDH2,SLC37A1,KIAA0040,EAF2,SAV1,RHOB,BANK1,SWAP70,ITPR1,RAB31,ZNF165,TLE1,DLAT,MAPK12 |
| 3.002e-03 | -5.81 | Cyclin A/B1 associated events during G2/M transition | REACTOME pathways | R-HSA-69273 | 22 | 9 | 8202 | 1235 |
PLK1,WEE1,CCNA2,FOXM1,PKMYT1,CCNB1,CCNB2,CDC25C,CDK1 |
| 3.010e-03 | -5.81 | TRPC1 (transient receptor potential cation channel, subfamily C, member 1) | protein interactions | 7220 | 21 | 9 | 16036 | 2547 |
MX1,RHOA,ITPR1,TRPC1,PKD2,ITPR2,ITPR3,TRPC3,MDFI |
| 3.010e-03 | -5.81 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | 408 | 80 | 17758 | 2588 |
FAM171B,FOXO6,ARMCX3,NDRG1,RHBDL3,SH3KBP1,PER2,SIPA1L2,ENTPD4,FAM46A,PAPSS1,DAB2IP,DIXDC1,LGMN,ARMCX6,EGLN3,LOXL1,DOCK4,CD55,MARK1,DUSP4,LDB2,C15orf39,EDNRA,NFIX,AHRR,ENPP1,KLF12,ANKRD6,P4HA2,TSPAN18,ZNF704,KLF11,SYT13,PDXK,ISOC1,BMF,FARP1,NUAK1,UBASH3B,CTSB,ARL4C,SLC1A3,FBLN1,TTYH3,BMP2K,LMNA,PARM1,NRP2,IRF2BPL,DNPEP,OXCT1,PTEN,KNDC1,C10orf54,C9orf72,ATP2B1,IGDCC4,CHSY3,REC8,RAB3B,ANTXR1,ABLIM2,CD83,IL1R1,CACHD1,SERTAD2,COL13A1,RND3,FGF18,MATN2,DGAT2,RHOBTB2,NR4A2,PKD2,CENPE,AHR,DEF6,KLF7,IRF1 |
| 3.012e-03 | -5.81 | protein ubiquitination | biological process | GO:0016567 | 628 | 119 | 16441 | 2455 |
LMO7,CCNC,UNKL,PAX6,TRIM2,TRIM24,TRIM5,SUZ12,PSME2,CUL4B,WDTC1,XIAP,FBXO2,CUL1,UBE2Z,UBE2Q1,PSME1,RNF182,HDAC6,PJA2,KBTBD11,BARD1,SPSB1,TRIM68,PSMD1,RNF220,UBE2T,MKRN3,PSMC2,MARCH2,RNF169,PLK1,SIRT1,TRIM8,FBXL16,AKT1,TCEB2,ITCH,CDC20,RNF11,RNF165,PRKCQ,CCNF,ASB13,CBL,RNF19B,VCP,SOCS3,TRIM9,PSMD3,PEX2,WWTR1,AREL1,TRAF5,PSMC1,ZC3HC1,PINK1,KLHL13,SHPRH,DCAF7,TRAF2,ASB9,PSMD7,CDCA3,CBLL1,PSMD10,HERC5,FBXO6,ZNRF3,HERC6,TSPAN17,WWP2,SH3RF2,MARCH8,DTX3L,UBE2Q2,IRAK1,RNF128,ZNRF2,FBXO7,FBXL14,UBE2J1,TRIM21,TRIM3,WWP1,RAG1,MYLIP,TRIM62,PSMA5,SOCS5,DDB2,DCAF6,PSMB4,AMFR,SHARPIN,RC3H2,NUB1,UBE2A,KBTBD8,FBXO9,UBAC1,PELI3,NEURL1B,PSMA4,FBXO10,G2E3,KLHL2,DCAF10,TRIM69,PELI2,KBTBD2,DTX4,UBE2D2,ARRB1,UBE2C,RUSC1,RNF146,FBXW5,PHC1 |
| 3.016e-03 | -5.80 | WANG_CLIM2_TARGETS_UP | MSigDB lists | WANG_CLIM2_TARGETS_UP | 217 | 47 | 17758 | 2588 |
OTUD5,SEMA6B,ACACB,REPS2,S100A11,BVES,ERCC6L,COL18A1,CYB561,BCL2L1,MERTK,RAVER2,TP73,CALR,CD109,ANKS6,BMP7,PAK2,PLK4,IGFBP2,NPTXR,LMAN1,NAGA,SMC4,IGSF3,CXXC5,CASK,TRIM8,DENND1B,MRS2,SRSF5,ALCAM,MYL12A,LEPR,COL12A1,SGPP1,USP6,PTPRF,DNAJC10,TAPBP,TIMP3,CAMK2N2,SLC25A40,ARAP1,FBXO44,KLK7,F2RL1 |
| 3.020e-03 | -5.80 | NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON | 124 | 30 | 17758 | 2588 |
CCNE2,CTHRC1,FAM92A1,GRHL2,RIPK2,STAU2,ESRP1,OSGIN2,GGH,INTS8,OSR2,LACTB2,COX6C,SPAG1,FZD6,NKAIN3,OTUD6B,PEX2,MATN2,ZNF704,SNX16,MRPS28,TMEM64,ATP6V1C1,GEM,TRAM1,TTPA,NCOA2,RIMS2,PKIA |
| 3.027e-03 | -5.80 | Adipogenesis | WikiPathways | WP236 | 131 | 34 | 4455 | 729 |
SLC2A4,EPAS1,GATA3,GTF3A,LPIN3,CYP26A1,LMNA,BMP2,RB1,CTNNB1,GATA2,IL6ST,TWIST1,NCOA2,CYP26B1,WNT10B,NR3C1,PPARA,FAS,ZMPSTE24,SOCS3,IRS2,AGPAT2,RBL1,STAT6,WWTR1,BMP1,STAT1,E2F1,KLF5,HMGA1,AHR,LIFR,KLF7 |
| 3.034e-03 | -5.80 | MODULE_519 | MSigDB lists | MODULE_519 | 15 | 7 | 17758 | 2588 |
PDIA3,ALDH7A1,IDH1,ERP29,P4HB,PDIA4,PDIA5 |
| 3.034e-03 | -5.80 | ZEMBUTSU_SENSITIVITY_TO_DOXORUBICIN | MSigDB lists | ZEMBUTSU_SENSITIVITY_TO_DOXORUBICIN | 15 | 7 | 17758 | 2588 |
MORF4L2,CCNB1,GAB1,IL6ST,GPC3,EPS8L2,PARP9 |
| 3.034e-03 | -5.80 | chrxq23 | MSigDB lists | chrxq23 | 15 | 7 | 17758 | 2588 |
CAPN6,KLHL13,BHLHB9,ALG13,CUL4B,ZBTB33,RGAG1 |
| 3.034e-03 | -5.80 | ZHAN_LATE_DIFFERENTIATION_GENES_DN | MSigDB lists | ZHAN_LATE_DIFFERENTIATION_GENES_DN | 15 | 7 | 17758 | 2588 |
SORL1,MYBL1,SYK,BIK,EPHX1,CKS2,BCL6 |
| 3.034e-03 | -5.80 | BIOCARTA_AKAPCENTROSOME_PATHWAY | MSigDB lists | BIOCARTA_AKAPCENTROSOME_PATHWAY | 15 | 7 | 17758 | 2588 |
PRKAR2B,RHOA,PPP1CA,PKN1,MAP2,CDK1,NUP85 |
| 3.034e-03 | -5.80 | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORSNAD_OR_NADP_AS_ACCEPTOR | MSigDB lists | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORSNAD_OR_NADP_AS_ACCEPTOR | 15 | 7 | 17758 | 2588 |
ALDH3B1,ALDH7A1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 3.041e-03 | -5.80 | V$OCT1_05 | MSigDB lists | V$OCT1_05 | 234 | 50 | 17758 | 2588 |
PAX6,THRA,MRAS,HOXB2,PPP2R3A,SLC9A7,NRP2,SCML1,TFAP4,FOXP2,SCNN1A,ADORA1,PTEN,RGS3,LHX6,CNNM4,TSPAN13,MANF,PDE4D,PIM1,DGKG,ARAP2,ING1,PLEKHA6,ELK3,FZD4,DENND1B,STAT4,ITCH,SERTAD4,LDB2,ITPR3,FOS,RHOB,COL12A1,NIN,DPYSL3,ENPP1,PROM1,ALDH5A1,GPRC5B,FGFR2,NEIL3,NR4A3,CTNND1,TMOD2,SP6,ARHGAP4,CEP41,TLL2 |
| 3.052e-03 | -5.79 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | MSigDB lists | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | 63 | 18 | 17758 | 2588 |
MX1,IFITM3,HLA-F,USP18,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,STAT1,IRF2,IRF7,HLA-C,OAS3,RNASEL,IFIT1,IFI6,IRF1 |
| 3.055e-03 | -5.79 | Role of phospholipids in phagocytosis | REACTOME pathways | R-HSA-2029485 | 26 | 10 | 8202 | 1235 |
PLCG1,PLCG2,ITPR1,PIK3R1,PIK3CA,PLD2,ITPR2,PLD1,ITPR3,SYK |
| 3.056e-03 | -5.79 | hair follicle development | biological process | GO:0001942 | 76 | 21 | 16441 | 2455 |
LGR4,LRP4,SOX9,TFAP2C,SAV1,LDB2,TNFRSF19,FZD6,EGFR,ZDHHC21,GNAS,PDGFA,CD109,CTNNB1,FGFR2,CTSV,DBI,SMO,HDAC1,ERCC2,HOXC13 |
| 3.060e-03 | -5.79 | retroperitoneum | COSMIC cancer mutations | retroperitoneum | 31 | 11 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3R1,SMO,PIK3CA,ERBB2,IDH1,FLT3,EGFR |
| 3.073e-03 | -5.79 | adrenal_gland-adrenal_gland-adrenal_cortical_neoplasm-cortisol_producing | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_neoplasm-cortisol_producing | 3 | 3 | 17775 | 2585 |
GNAS,CTNNB1,TP53 |
| 3.073e-03 | -5.79 | meninges-meningioma-angiomatous-microcystic | COSMIC cancer mutations | meninges-meningioma-angiomatous-microcystic | 3 | 3 | 17775 | 2585 |
NF2,AKT1,SMO |
| 3.073e-03 | -5.79 | angiomatous-microcystic | COSMIC cancer mutations | angiomatous-microcystic | 3 | 3 | 17775 | 2585 |
NF2,AKT1,SMO |
| 3.073e-03 | -5.79 | meninges-meningioma-fibroblastic-transitional | COSMIC cancer mutations | meninges-meningioma-fibroblastic-transitional | 3 | 3 | 17775 | 2585 |
NF2,AKT1,SMO |
| 3.073e-03 | -5.79 | fibroblastic-transitional | COSMIC cancer mutations | fibroblastic-transitional | 3 | 3 | 17775 | 2585 |
NF2,AKT1,SMO |
| 3.074e-03 | -5.78 | OTU_dom | interpro domains | IPR003323 | 15 | 7 | 18293 | 2672 |
OTUB2,OTUD5,YOD1,OTUD1,ZRANB1,OTUD6B,ALG13 |
| 3.084e-03 | -5.78 | TGFB3 (transforming growth factor beta 3) | protein interactions | 7043 | 14 | 7 | 16036 | 2547 |
TGFBR1,TGFBR3,CTGF,ACVRL1,VASN,LTBP3,SDC4 |
| 3.086e-03 | -5.78 | intracellular receptor signaling pathway | biological process | GO:0030522 | 185 | 42 | 16441 | 2455 |
DDX58,NKX3-1,TXN,TAB3,THRA,P2RX7,BCL2L1,NOTCH2,CALR,RB1,CTNNB1,SP100,IRAK1,CRY2,PIM1,MAP3K7,MED30,NCOA2,THRB,RHOA,RIPK2,NR3C1,NR4A1,ITCH,FHL2,PPARA,PDK3,KDM3A,NCOA3,NR1D2,TBX1,NFKBIA,NR4A3,PIAS2,NOD2,IRF7,NR4A2,GPER1,IFIH1,AHR,ARNT,RARG |
| 3.086e-03 | -5.78 | membrane lipid metabolic process | biological process | GO:0006643 | 185 | 42 | 16441 | 2455 |
UGT8,HEXB,P2RX7,ASAH1,TEX2,PLD2,B4GALT4,PIGL,PGAP1,SGPL1,B4GALNT1,ITGB8,ARSG,A4GALT,SERINC2,BAX,NAGA,ALDH3A2,GM2A,CERS2,CYP1B1,PIGC,PLAUR,SPTLC2,ARSK,CPTP,SGPP1,GPLD1,KDSR,ALDH3B1,ALDH5A1,FA2H,PLPP3,PLA2G15,CTSA,SAMD8,GLB1,PLD1,GLA,ARSB,ST3GAL1,KDELC2 |
| 3.087e-03 | -5.78 | ETSDOMAIN | prints domains | PR00454 | 28 | 10 | 4759 | 661 |
ELK4,ELK3,ETS2,ETV5,ELF5,ELK1,ETV7,ETV4,ETS1,ELF3 |
| 3.091e-03 | -5.78 | positive regulation of cysteine-type endopeptidase activity | biological process | GO:2001056 | 137 | 33 | 16441 | 2455 |
CASP3,NKX3-1,DAP,TRAF2,RET,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,DAPK1,BAX,CDKN1B,WNT3A,EGLN3,F2R,SIRT1,RHOA,ACVR1C,CASP9,SLC11A2,BCL2L13,CYFIP2,VCP,BCL10,FAS,CASP7,NGFRAP1,ARRB1,GPER1,MAP3K5,XDH |
| 3.105e-03 | -5.77 | inositol phosphate metabolic process | biological process | GO:0043647 | 57 | 17 | 16441 | 2455 |
INPPL1,INPP5D,CALM1,CALM3,ISYNA1,EPM2A,CALM2,PLCG1,PLCH1,INPP5E,PTEN,OCRL,PLCG2,INPP4B,MINPP1,ITPKA,PLCB2 |
| 3.105e-03 | -5.77 | positive regulation of phosphatidylinositol 3-kinase signaling | biological process | GO:0014068 | 57 | 17 | 16441 | 2455 |
NKX3-1,SOX9,ERBB2,CBL,PDGFB,FLT3,PDGFA,FYN,SEMA4D,PIK3AP1,NRG1,MYDGF,ERBB3,GPER1,UNC5B,F2RL1,F2R |
| 3.113e-03 | -5.77 | ROZANOV_MMP14_TARGETS_SUBSET | MSigDB lists | ROZANOV_MMP14_TARGETS_SUBSET | 31 | 11 | 17758 | 2588 |
MDK,TIMP3,COL6A2,NR3C1,PLOD2,CALD1,COL6A1,MATN2,COL18A1,PLXND1,SULF2 |
| 3.113e-03 | -5.77 | MOSERLE_IFNA_RESPONSE | MSigDB lists | MOSERLE_IFNA_RESPONSE | 31 | 11 | 17758 | 2588 |
DDX58,MX1,USP18,STAT1,HERC5,SAMD9,IFIT1,CD274,CMPK2,IFIT3,IFIH1 |
| 3.113e-03 | -5.77 | AMIT_SERUM_RESPONSE_40_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_40_MCF10A | 31 | 11 | 17758 | 2588 |
WEE1,TCTN2,NR4A1,ZFP36,FOSB,NR4A2,LGMN,CITED2,FOS,GM2A,DUSP1 |
| 3.113e-03 | -5.77 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP | 31 | 11 | 17758 | 2588 |
SPP1,TIMP3,WDR44,GPC3,NEK2,DAPK1,TMEM98,EMP3,SGK1,DUSP1,WBP5 |
| 3.113e-03 | -5.77 | PROTEIN_AMINO_ACID_AUTOPHOSPHORYLATION | MSigDB lists | PROTEIN_AMINO_ACID_AUTOPHOSPHORYLATION | 31 | 11 | 17758 | 2588 |
MAP3K3,TNK1,INSR,IGF1R,AKT1,CDKL5,PAK2,MAP3K11,KIAA1804,MAP3K9,EIF2AK1 |
| 3.113e-03 | -5.77 | BIOCARTA_EGF_PATHWAY | MSigDB lists | BIOCARTA_EGF_PATHWAY | 31 | 11 | 17758 | 2588 |
PLCG1,JAK1,STAT4,STAT6,PIK3R1,STAT1,PIK3CA,ELK1,FOS,EGFR,RASA1 |
| 3.113e-03 | -5.77 | Nuc_orph_rcpt | interpro domains | IPR003070 | 3 | 3 | 18293 | 2672 |
NR4A2,NR4A1,NR4A3 |
| 3.113e-03 | -5.77 | InsP3_rcpt-bd | interpro domains | IPR000493 | 3 | 3 | 18293 | 2672 |
ITPR2,ITPR3,ITPR1 |
| 3.114e-03 | -5.77 | tissue migration | biological process | GO:0090130 | 81 | 22 | 16441 | 2455 |
EPB41L5,GRHL2,NR4A1,TGFBR1,LOXL2,EGR3,PKN1,ANLN,EMP2,S100A2,CORO1B,GPLD1,NOV,PTEN,SCG2,PIK3CA,STAT1,ACTA2,EPHB4,PLXND1,ARSB,CYP1B1 |
| 3.114e-03 | -5.77 | mitotic sister chromatid segregation | biological process | GO:0000070 | 81 | 22 | 16441 | 2455 |
PLK1,PSRC1,ZWINT,DLGAP5,PAPD7,CIT,NDC80,VPS4B,CDCA8,NUSAP1,KIF2C,CCNB1,SPDL1,RB1,KIF14,CDCA5,NEK2,CHMP4B,KIF22,CENPE,ESPL1,SMC4 |
| 3.123e-03 | -5.77 | WIERENGA_STAT5A_TARGETS_DN | MSigDB lists | WIERENGA_STAT5A_TARGETS_DN | 195 | 43 | 17758 | 2588 |
PLEKHG3,BIN1,WASF3,ARHGEF3,ARAP3,LMTK3,DEPDC1,UBASH3B,CTDSPL,PDIA5,RASGRP3,VASH1,ETS1,C1orf116,TMEM63A,CCND1,ZYX,XYLT2,PLCG2,CD9,IL17RA,MTMR11,HEXIM2,FAR2,PLCB2,SLC12A2,SUSD3,PPIF,TRIM8,PSRC1,SLC37A1,C3orf52,MYEOV,EAF2,ILK,LHFPL2,CLCN2,SPNS3,NFIB,IRS2,BANK1,MYLK,SH3BGRL2 |
| 3.123e-03 | -5.77 | GSE27786_CD4_TCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_NKTCELL_UP | 195 | 43 | 17758 | 2588 |
LZTFL1,ITGA6,MAPK4,MAP1LC3B,SDF4,KIF5B,ACAP2,RALGPS2,PPP1R10,DPYSL2,FAM13B,CAPG,FAM63A,ZNF692,BRAT1,RNASEH2A,STK35,SMC4,CASK,NR4A1,SH3BGRL,DBR1,CALCRL,PRICKLE1,TNFAIP8L1,XRCC6BP1,RNF19B,CASP4,ATP10D,SP4,MAN2A2,DCTN6,PLCG1,DGCR2,ETS2,SETD3,SLC35B3,NAB2,NFKBIA,DGAT2,ATP1B3,SHROOM2,RAD21 |
| 3.123e-03 | -5.77 | GSE22886_NEUTROPHIL_VS_DC_DN | MSigDB lists | GSE22886_NEUTROPHIL_VS_DC_DN | 195 | 43 | 17758 | 2588 |
TXN,MRPS15,ADO,CUL1,HMGN3,GSTP1,KTN1,M6PR,CAPN2,PSMD1,ATP5H,FBXO7,PSMC2,MITF,OPN3,FBXL14,MDFIC,CITED2,TRAM1,TIAM1,METAP2,SOAT1,SYPL1,PCCB,TGIF1,PTPN18,GCLC,CLSTN1,GLO1,MRPS35,ATP1B1,GTF2A2,PDHX,VCP,ANKRD10,PRDX3,DNM1L,SLC9A6,IARS2,MAOA,NUP37,AKIP1,CD81 |
| 3.132e-03 | -5.77 | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | MSigDB lists | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | 68 | 19 | 17758 | 2588 |
PLA2G4A,CENPA,FURIN,COL18A1,OAT,PDGFA,ZFX,TIMP3,TIMP1,CTGF,RBL1,GATA2,DCK,CSF1,PLK4,ACTA2,NCAM1,S100A6,CYP1B1 |
| 3.144e-03 | -5.76 | thyroid-carcinoma-papillary_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-papillary_carcinoma | 114 | 28 | 17775 | 2585 |
TRIM24,AKT1,ASPM,SYNE2,RET,PIK3R1,TP53,ERBB2,IDH1,FLT3,KTN1,GNA11,EGFR,GNAS,KIF5B,RB1,CTNNB1,FAT4,CDH1,PTEN,FGFR2,CCDC6,SMO,PIK3CA,SPTBN5,TFG,JAK3,PRKAR1A |
| 3.144e-03 | -5.76 | papillary_carcinoma | COSMIC cancer mutations | papillary_carcinoma | 114 | 28 | 17775 | 2585 |
TRIM24,AKT1,ASPM,SYNE2,RET,PIK3R1,TP53,ERBB2,IDH1,FLT3,KTN1,GNA11,EGFR,GNAS,KIF5B,RB1,CTNNB1,FAT4,CDH1,PTEN,FGFR2,CCDC6,SMO,PIK3CA,SPTBN5,TFG,JAK3,PRKAR1A |
| 3.147e-03 | -5.76 | POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 162 | 37 | 17758 | 2588 |
TAOK2,RALBP1,TRAF2,TP53,ERBB2,PKN1,CARD10,PICK1,CCND1,CARD8,IRAK1,MAP3K9,BAX,SERINC2,MDFIC,MAP3K7,F2R,PLCB2,CCDC88A,MDFI,SOD1,CASP9,STRADB,MAP3K6,VCP,EGFR,EDNRA,GNAS,PPP2R4,MADD,STAT1,KIAA1804,ARAP1,MAP3K11,MAP3K5,AIFM3,CD81 |
| 3.153e-03 | -5.76 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN | 184 | 41 | 17758 | 2588 |
CMAS,UGP2,DAP,CENPI,CNOT8,RASGRP3,KIF2C,ITPR2,MNS1,ECI1,NAPG,DAZAP1,PDCD10,PHF7,MGAT1,ASH2L,CLIP2,TIAM1,TPCN1,CLCN3,PGM1,ELK3,HN1L,AGPS,PTPN9,PDK3,RAD17,BCL2L13,ICMT,SKA1,PDHX,DDX23,OSBPL2,SWAP70,CDK19,P4HA2,TDRD7,MDH1,NRGN,PSMC1,MAPK12 |
| 3.153e-03 | -5.76 | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP | 184 | 41 | 17758 | 2588 |
MRPS9,INPPL1,FRMD4A,GNPDA1,MRAS,PKN1,ELMOD2,LBR,CORO1B,TMEM63A,CCDC92,MARCH8,FAM111A,IGF1R,CEP78,PCYOX1,IL17RA,C10orf54,SLC39A10,NDUFA12,CNPY3,NUP85,CRTAP,MSH6,CAMK2G,MBP,MBNL3,CLSTN1,TTC7A,PDK3,ICMT,ZNF641,CTNS,STX10,PRCP,SH2D3C,ZMYND19,CDCA7L,IARS2,PGM2L1,CD33 |
| 3.153e-03 | -5.76 | GSE22886_NAIVE_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NKCELL_UP | 184 | 41 | 17758 | 2588 |
ACVR1,CCDC109B,ST13,ENO2,DHPS,DGKA,AES,NENF,SORBS3,ERP29,PHF1,PSIP1,AIP,EPS8L2,TMEM63A,KCNN4,FABP6,PASK,MDFIC,SMYD5,ABCC1,SYPL1,FBLN5,ASXL1,UXT,COX11,PRKRA,PLEKHB1,LDLRAP1,PAFAH1B3,SPINT2,INPP4B,TTC9,TMEM159,RGS14,RPL22,TBC1D4,NDFIP1,TOB1,PKIA,FAM134B |
| 3.159e-03 | -5.76 | aryl hydrocarbon receptor complex | cellular component | GO:0034751 | 3 | 3 | 17570 | 2579 |
AHRR,AHR,AIP |
| 3.160e-03 | -5.76 | canonical Wnt signaling pathway | biological process | GO:0060070 | 91 | 24 | 16441 | 2455 |
LGR4,WNT10B,PTPRU,FZD4,BCL9,GATA3,TCF7,ZNRF3,SDC1,FZD6,FZD7,CCND1,CTNNB1,PTEN,PTK7,PLPP3,MITF,SMO,CDH3,DIXDC1,FZD5,WNT3A,RARG,DVL2 |
| 3.161e-03 | -5.76 | SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | MSigDB lists | SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 88 | 23 | 17758 | 2588 |
ARAP3,RHOA,RALBP1,MRAS,ARHGDIB,PLD2,NOTCH2,RHOB,ABR,DIRAS3,TSC1,LIMK1,ARAP1,FGD6,TAX1BP3,PLD1,ARF6,ARHGAP4,ABCA1,RASGRP1,FGD1,DMPK,FARP2 |
| 3.162e-03 | -5.76 | MODULE_197 | MSigDB lists | MODULE_197 | 173 | 39 | 17758 | 2588 |
PAX6,CDKN1C,FOXM1,PTTG1,SOX9,ETV5,NDC80,KIF23,KIF2C,CCNB1,WEE1,CCNA2,HSF2,TFAP2A,GTF2F2,KIF22,BUB1,KNTC1,CITED2,GFI1,MYT1,NEK4,PLK1,SMARCA2,TAF5,PTGER4,MYBL2,WHSC1,FOS,CDK1,ETS2,E2F1,TLE1,KLF11,KPNA2,CCNB2,UBE2C,CBX4,RAD21 |
| 3.166e-03 | -5.76 | spindle microtubule | cellular component | GO:0005876 | 58 | 17 | 17570 | 2579 |
PLK1,PSRC1,CAPN6,CALM1,XIAP,PARP4,CALM3,NUSAP1,AURKB,SKA1,KIF11,CDK1,CALM2,PRC1,TUBG1,AURKA,KNTC1 |
| 3.171e-03 | -5.75 | Tetraspanin_EC2 | interpro domains | IPR008952 | 31 | 11 | 18293 | 2672 |
TSPAN15,CD63,TSPAN6,CD82,TSPAN18,CD9,TSPAN1,CD81,TSPAN17,TSPAN7,TSPAN33 |
| 3.178e-03 | -5.75 | BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | MSigDB lists | BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | 73 | 20 | 17758 | 2588 |
MX1,ARAP2,PARP12,IFITM3,SLC39A8,NUB1,UBE2Z,HERC5,CD274,IFIT3,CD40,CDK1,TDRD7,IRF7,IFIT1,OAS3,IFIH1,APOBEC3G,IFI6,LAMP3 |
| 3.189e-03 | -5.75 | MORF_MBD4 | MSigDB lists | MORF_MBD4 | 83 | 22 | 17758 | 2588 |
LAMP2,SYPL1,PSMB4,UGP2,RALBP1,PSMD7,MYL12A,PSMA4,DNPEP,SETD3,FAM20B,PSMC2,MDH1,PPP1CA,PSMC1,MYL12B,SLC35A1,CTBP1,TMED2,RAD21,PRKAR1A,EBAG9 |
| 3.189e-03 | -5.75 | TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 83 | 22 | 17758 | 2588 |
SORBS1,AGRN,REPS2,AKT1,MPZL1,EPS8,PIK3R1,ERBB2,ERBB2IP,ROR1,CBL,BCAR1,FLT3,EGFR,PICK1,PTPRJ,INSR,IGF1R,SHC3,ERBB3,GAB1,FRS3 |
| 3.189e-03 | -5.75 | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | MSigDB lists | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | 83 | 22 | 17758 | 2588 |
ADAMTS2,COL9A3,COL6A2,PCOLCE,TIMP2,FURIN,COL4A5,COL7A1,COL12A1,MMP15,TIMP1,P4HB,COL13A1,PLOD2,MMP17,COL6A1,BMP1,ADAMTS14,PLOD3,COL16A1,CRTAP,TLL2 |
| 3.196e-03 | -5.75 | BHAT_ESR1_TARGETS_VIA_AKT1_DN | MSigDB lists | BHAT_ESR1_TARGETS_VIA_AKT1_DN | 78 | 21 | 17758 | 2588 |
CPEB4,SNTB2,EPS8,ATP1B1,BCL2L1,SYTL2,BCAR3,IL1R1,GRHL1,SHROOM3,TRIM45,CDH3,ZDHHC7,TLE1,PLEKHF1,EFNA1,FAM84B,KLF9,SLC16A5,RARG,IGSF3 |
| 3.197e-03 | -5.75 | SMIRNOV_RESPONSE_TO_IR_2HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_2HR_UP | 49 | 15 | 17758 | 2588 |
ELK4,PLK2,SOX9,RAB11FIP1,PTGER4,SGK1,KLF5,GDF15,PIM1,RNF19B,SESN1,TNFSF9,FAS,CD83,IER3 |
| 3.197e-03 | -5.75 | PID_ARF6_TRAFFICKING_PATHWAY | MSigDB lists | PID_ARF6_TRAFFICKING_PATHWAY | 49 | 15 | 17758 | 2588 |
BIN1,SLC2A4,ITGA3,CTNNB1,CDH1,ITGA7,ITGA6,VAMP3,DNM2,CTNND1,PLD2,ITGAV,PLD1,ARF6,CPE |
| 3.197e-03 | -5.75 | VANTVEER_BREAST_CANCER_POOR_PROGNOSIS | MSigDB lists | VANTVEER_BREAST_CANCER_POOR_PROGNOSIS | 49 | 15 | 17758 | 2588 |
CCNE2,RTN4RL1,CENPA,OXCT1,DCK,FGF18,EBF4,PRC1,NDC80,ECI2,GPR180,NUSAP1,QSOX2,MELK,ZNF385B |
| 3.197e-03 | -5.75 | PID_PI3KCI_PATHWAY | MSigDB lists | PID_PI3KCI_PATHWAY | 49 | 15 | 17758 | 2588 |
PLCG1,FYN,INPPL1,ARAP3,RHOA,PTEN,INPP5D,PLCG2,PIK3R1,PIK3CA,SGK1,PIK3CD,YES1,ARF6,SYK |
| 3.206e-03 | -5.74 | oxidation-reduction process | biological process | GO:0055114 | 1017 | 183 | 16441 | 2455 |
CFAP61,ACACB,GAA,TXN,AASS,CRYM,CPT2,SLC25A13,CACNA2D2,ITPR2,ECI1,ASPHD2,CALM2,CYP1A1,IL6ST,CYP2S1,ALDH1A3,RDH14,STEAP2,KCNS3,AOX1,AKR1B1,PPP1CA,ACOX2,TECR,CYP1B1,SOD1,PRKAR2B,LOXL2,SLC25A5,IDH1,MRPS36,TP53I3,CYP4F3,POR,KDM4D,KDSR,FASTKD1,SLC25A4,DHRS13,UEVLD,P4HA2,DHTKD1,ADIPOR1,PDPR,PPP2R5D,DLAT,PRKAA2,FAM213B,PPP1R2,ALDH6A1,CYP2J2,PYROXD2,ADO,PRKAA1,SLC25A27,CALM3,NDUFA4,SLC1A3,COX6C,DHRS3,RSAD1,QSOX2,BMP2,PFKL,ATP5H,BDH1,PCYOX1,CACNA1D,FAR2,ACAD8,MOXD1,NDUFA12,PHKG2,ALDH3A2,CYP26B1,GFPT1,FADS2,PMPCB,PRODH,QSOX1,OXR1,CALM1,ERO1A,PYGL,PKM,KDM3A,STEAP1,CYB5A,GNAS,DHDH,PRKAG2,FA2H,P4HA3,ITPR1,MDH1,FAM213A,CTBP1,XDH,EGLN1,UGP2,NQO1,IQGAP1,P3H2,TMX4,PDIA5,SOD2,GMPR,FTH1,MGST2,AIFM2,PRKACA,CYP39A1,GNB2,CYP26A1,EPM2A,PER2,CYP4F11,GYS1,VAT1,STEAP3,PHKA2,ETHE1,EGLN3,LOXL1,FAR1,GPX4,AKT1,PFKFB2,AGPS,CYB5R2,ACO1,HTATIP2,ITPR3,AKR1E2,COX20,DNAJC10,DUOX1,ALDH3B1,PTGS2,ALDH5A1,ACAD10,PEX2,MAOA,TRABD2A,PPP1CB,CYP2U1,C1orf43,AIFM3,PRKAR1A,PINK1,ENO2,SCD5,BLVRB,OSGIN2,PDIA3,CYB561,SPR,LBR,FDXR,BAX,ECI2,ALDH7A1,ABCD1,TMX1,OSGIN1,PGM1,PCCB,ALDH2,OGDHL,BLVRA,LEPR,PRDX4,MARC1,ACADSB,PLOD2,PRDX3,DHRS2,NR4A3,PGM2L1,ACADM,PLOD3,CYBRD1 |
| 3.228e-03 | -5.74 | RUTELLA_RESPONSE_TO_HGF_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_DN | 229 | 49 | 17758 | 2588 |
CCNI,SIGIRR,ZNF395,CDKN1C,HLA-E,TMX4,PDIA5,SELL,IL13RA1,GTF3A,NOTCH2,CCNL1,ARHGEF40,TSEN34,HDAC9,APLP2,DPYSL2,ZFP36,SORL1,EGLN3,CNPY3,SLC16A5,TUBA4A,CD55,PLSCR1,RUNX3,ZFAND5,SPTLC2,MAP3K6,STK17B,CD83,RASGRP2,MAN2A2,BTG1,FYN,MPRIP,ETS2,SPINT2,RAB11FIP1,CCDC69,NRG1,NR4A2,LRRK1,NDE1,RPL22,TRAF5,CHPT1,F2RL1,LTA4H |
| 3.257e-03 | -5.73 | TSC2 (tuberous sclerosis 2) | protein interactions | 7249 | 63 | 19 | 16036 | 2547 |
PLK1,SIRT1,AKT1,RPS6KA1,CALM1,PRKAA1,PNKD,RHEB,MAPKAPK2,CCND1,TSC1,SPINT2,DAPK1,CDKN1B,RP2,ALDH3A2,FBXW5,MDFI,RRAGD |
| 3.272e-03 | -5.72 | MULLIGHAN_MLL_SIGNATURE_1_UP | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_1_UP | 362 | 72 | 17758 | 2588 |
ARHGAP11A,LAMP1,RPS6KA1,HEXB,TGOLN2,MGST2,HDAC6,DENND2D,REPS1,SDF4,PER2,RBM23,NUP210,KHNYN,P4HB,IQCE,CAPG,DNM2,IL10RB,SNX10,PPIF,S100A4,PTPN9,HTATIP2,EAF2,C15orf39,RNF19B,ABR,LCP1,SLC9A6,HOXA9,SH3GLB2,TDRD7,EIF4EBP2,MAPK13,RGS14,SLC27A3,NXT2,GRN,ARHGEF3,TRAPPC10,RASSF7,PBX3,EFHD2,RAB6A,ARHGEF40,SIRPA,SAC3D1,M6PR,GNS,RAC2,IRAK1,TBCD,RRBP1,ZDHHC13,IL17RA,CNPY3,SYK,ALDH3A2,S100A6,NAGPA,SNTB1,RNPEP,NUBP1,DDX23,FUCA1,INSR,ITGA7,SFMBT1,PITPNA,CTSA,ARPC2 |
| 3.274e-03 | -5.72 | central_nervous_system-midbrain-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-midbrain-glioma-astrocytoma_Grade_I | 27 | 10 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,RET,SMO,PIK3CA,IDH1,GNA11,EGFR |
| 3.274e-03 | -5.72 | skull | COSMIC cancer mutations | skull | 27 | 10 | 17775 | 2585 |
GNAS,RB1,CTNNB1,AKT1,PTEN,PIK3CA,TP53,IDH1,FLT3,EGFR |
| 3.274e-03 | -5.72 | acinar_adenocarcinoma | COSMIC cancer mutations | acinar_adenocarcinoma | 27 | 10 | 17775 | 2585 |
KIF5B,CTNNB1,AKT1,FGFR2,PTEN,SDC4,PIK3CA,TP53,ERBB2,EGFR |
| 3.278e-03 | -5.72 | GRADE_COLON_CANCER_UP | MSigDB lists | GRADE_COLON_CANCER_UP | 817 | 147 | 17758 | 2588 |
LAMP1,GAA,TXN,CCNO,PSME1,NENF,PLXNA1,MORF4L2,FAM101B,TRIM68,CHPF,ZYX,PCNA,CTNNB1,CYP2S1,ATP13A3,CAPG,ABCA2,CTTN,TECR,MGAT5,ORAI2,CXXC5,RNF165,TNS1,POR,PIAS3,MAPK13,GRN,CD99,ITGA6,SOX9,NDUFA4,TTYH3,PDXDC1,RABGGTA,CALR,DAZAP1,GATA2,KCNN4,ATP5H,MEGF8,VASN,RANBP1,FXYD5,SRP54,CD70,TNFRSF12A,BRAT1,FAM84B,GAD1,SLC12A2,EEF1D,PSMA5,MCCC2,PCDH1,MFI2,BTNL9,SPATA13,SCRIB,ZDHHC3,TSC1,SLCO4A1,SLC6A6,ARPC2,CBX5,IFI6,FBXW5,GPR107,S100A11,CD82,COL18A1,PCBP1,BCAP31,GNB2,EPS8L2,IER3,RAD23A,RCN1,ZDHHC12,GLB1L2,ETV4,SEPHS1,CKS2,GPX4,PPIF,SEC61B,TCEB2,AGPS,TMEM43,CDC20,RAD17,ITPR3,GIGYF1,HSF4,TAPBP,DDOST,STX10,STAT6,HAGHL,PDXK,ARHGAP4,RPL22,HSP90B1,MPZL1,TRAPPC10,CD63,CTSB,BACE1,DCAF7,CYB561,GTF3A,PKN1,GSTP1,PDIA4,TOP2A,ADD3,CEP97,ADRBK1,IRAK1,CDK16,A4GALT,MCF2L,FAM102A,H2AFY,TMBIM6,ADAM15,TAGLN2,S100A6,PVRL4,TGIF1,CASK,MLEC,PSMB4,PARP4,NUCB1,DDAH1,TMEM50B,HNRNPH2,NMI,SSNA1,HMGA1,PLOD3,USF2,UBE2C,OCLN,ESYT2 |
| 3.284e-03 | -5.72 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | molecular function | GO:0005220 | 3 | 3 | 16491 | 2452 |
ITPR2,ITPR3,ITPR1 |
| 3.284e-03 | -5.72 | TAP2 binding | molecular function | GO:0046979 | 3 | 3 | 16491 | 2452 |
TAPBP,HLA-F,TAP1 |
| 3.284e-03 | -5.72 | oncostatin-M receptor activity | molecular function | GO:0004924 | 3 | 3 | 16491 | 2452 |
OSMR,LIFR,IL6ST |
| 3.284e-03 | -5.72 | N-terminal myristoylation domain binding | molecular function | GO:0031997 | 3 | 3 | 16491 | 2452 |
CALM3,CALM2,CALM1 |
| 3.284e-03 | -5.72 | negative regulation of growth | biological process | GO:0045926 | 235 | 51 | 16441 | 2455 |
GAS2L1,SEMA6B,TNK1,NF2,SERPINE2,TP53,TP73,CDKN2C,NOV,SPP1,PTEN,GPC3,BCL6,ADAM15,CDKN1B,MAPK11,SEMA3G,LGMN,NTN1,WNT3A,CDKN2D,OSGIN1,SEMA3B,SIRT1,SMARCA2,CDKN2AIP,PSRC1,ING1,SERTAD3,CDA,EAF2,SAV1,NDRG3,BBS2,CDK5R1,ULK2,GNAS,JADE1,ENPP1,BTG1,SERTAD2,PTPRJ,SEMA4D,ACVRL1,CGREF1,NKD1,SH3BP4,NOD2,ADIPOR1,FHL1,SEMA3A |
| 3.285e-03 | -5.72 | SH2B2 (SH2B adaptor protein 2) | protein interactions | 10603 | 25 | 10 | 16036 | 2547 |
FYN,INPPL1,INSR,SORBS1,JAK1,AKT1,ERBB2,CBL,JAK3,SYK |
| 3.285e-03 | -5.72 | CD19 (CD19 molecule) | protein interactions | 930 | 25 | 10 | 16036 | 2547 |
FYN,CD22,CD82,PLCG2,PIK3R1,CD9,CR2,CBL,CD81,SYK |
| 3.285e-03 | -5.72 | ADAM10 (ADAM metallopeptidase domain 10) | protein interactions | 102 | 25 | 10 | 16036 | 2547 |
B3GNT2,TSPAN15,SH3D19,AXL,DLG1,PDIA3,EFNA1,FBXO6,TSPAN17,TSPAN33 |
| 3.294e-03 | -5.72 | RB_P130_DN.V1_DN | MSigDB lists | RB_P130_DN.V1_DN | 130 | 31 | 17758 | 2588 |
LAMP1,LAMP2,PVRL4,SEC23A,USP18,CTSB,ABCG2,KLK6,TXNDC9,GLO1,ASB13,IDH1,RASA1,KIAA1161,UHRF1BP1L,ZMPSTE24,GNS,ARHGAP24,RCN1,RB1,CTSC,STAT6,ZDHHC20,RAP2C,STAT1,ERAP1,KLK7,SELK,LIFR,C9orf72,PARP9 |
| 3.295e-03 | -5.72 | phosphatase activity | molecular function | GO:0016791 | 264 | 56 | 16491 | 2452 |
MTM1,DLGAP5,SSH1,PPM1J,UBASH3B,TMEM55B,INPP5D,CTDSPL,PHOSPHO1,PHLPP1,LPIN3,SBF1,PLPPR4,DUSP5,EPM2A,INPP5E,PTEN,ALPP,IMPAD1,OCRL,PPP4R1,PALD1,PAPL,DLG1,DUSP10,PPP1CA,PIKFYVE,MINPP1,PTPRE,CTDSP2,CAMK2G,DUSP1,SSH3,PTPN18,PFKFB2,PTPRU,PTPN9,PTPRH,DUSP23,PXYLP1,DUSP4,CDC25C,SGPP1,PTPRF,NUDT16,NT5C2,ATP1A1,PTPRJ,PLPP3,PHLPP2,INPP4B,PPM1H,PPP1CB,PPP2R5D,CPPED1,CTDSP1 |
| 3.296e-03 | -5.71 | lumenal side of membrane | cellular component | GO:0098576 | 31 | 11 | 17570 | 2579 |
CALR,HLA-B,TAPBP,NUCB1,HLA-E,HLA-F,PKD2,CTSA,HLA-C,BCAP31,HLA-A |
| 3.302e-03 | -5.71 | oligodendroglioma_Grade_III | COSMIC cancer mutations | oligodendroglioma_Grade_III | 316 | 64 | 17775 | 2585 |
EXPH5,ILDR1,RET,TP53,ERBB2,PLXNA1,CDKN2C,MUC16,CTNNB1,DNAH6,OSBPL3,PIK3CA,PHKA2,TIAM1,MYT1,NEB,TUBA4A,MYO5B,AKT1,TEP1,TANC1,IDH1,MAP3K6,PLEKHG6,HS6ST1,JAK1,SHROOM3,SLC9A6,MAP3K11,TANC2,UNC5B,AKNA,ABCA1,PCSK5,GLIS3,USH1C,PARP12,ARHGEF11,NOTCH2,SBF1,NEO1,RB1,PTEN,AIM1,PCYOX1,MSH2,PANX2,CACNA1D,MSH6,RIMS2,FARP2,WNT10B,PIK3R1,PDE5A,HEATR5A,RAB3IP,GNA11,EGFR,USP6,IL1R1,GNAS,NAB2,FZD5,PKD1L2 |
| 3.303e-03 | -5.71 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | 190 | 42 | 17758 | 2588 |
LZTFL1,RUNX2,HSP90B1,SEC61G,NDRG1,ATP8A1,CUL4B,TEX2,NUCB2,IL18R1,DUSP5,PDIA4,KIF5B,RAB15,TM9SF2,DACT1,MGAT4A,RRBP1,OPN3,UBE2J1,ANKRD12,MDFIC,LGMN,TRAM1,ITM2C,CCDC88A,TMED2,SEC61B,SEPT6,ITCH,DSTN,GLO1,CYFIP2,MAPKAPK2,DCK,SPINT2,FHL1,SPCS3,TMEM8B,TMEM14A,TBC1D4,CBX5 |
| 3.303e-03 | -5.71 | GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDM_DN | 190 | 42 | 17758 | 2588 |
SEMA6B,BCAM,FRMD6,HAL,MMADHC,OSGIN2,CCNL1,INTS8,NTAN1,PPP2R3A,BTG3,ST5,RPS6KA2,CCNA2,ELMO2,LLGL2,PRICKLE3,PPME1,LMO4,SRP54,CD70,MDFIC,HLA-C,CITED2,MYLIP,PTPRE,NCOA2,PLSCR1,SALL4,SYNE2,FURIN,CASP4,SOCS3,DHX32,ENDOD1,ETS2,KBTBD2,PSMD3,CTNND1,ANXA9,MAFF,EHD1 |
| 3.303e-03 | -5.71 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | 190 | 42 | 17758 | 2588 |
MAN1A2,HEXB,PDIA3,NENF,MORF4L2,CRABP2,DUSP5,ARHGEF16,LMNA,PDIA4,TM9SF2,MGAT1,FICD,RRBP1,FUT8,CD9,TMBIM6,TECR,NTN1,CITED2,GM2A,FAH,PODXL2,TIMP2,LAP3,DSTN,RAPGEF2,KDELR3,RHEB,FUCA1,INSR,UAP1,RCBTB2,GDE1,WIPI1,PRCP,ARFGAP3,SPCS3,PDXK,B4GALT3,HSPB1,MAPK12 |
| 3.307e-03 | -5.71 | ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES | MSigDB lists | ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES | 40 | 13 | 17758 | 2588 |
TAPBP,ATP1A1,RALBP1,ATP7B,ABCG2,ATP8B1,ATP1B3,ATP1B1,ATP6V1C1,ATP2B1,ABCD4,ABCG1,ABCC1 |
| 3.307e-03 | -5.71 | BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_DN | 40 | 13 | 17758 | 2588 |
LASP1,CASP7,SLC37A1,NFKBIE,SH3BP1,ANO6,AIM1,CTDSPL,ARFGAP3,BCL2L1,PRKRA,CCDC88A,FARP2 |
| 3.307e-03 | -5.71 | PRIMARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | PRIMARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 40 | 13 | 17758 | 2588 |
TAPBP,ATP1A1,SEC61B,ATP7B,ABCG2,ATP8B1,ATP1B3,ATP1B1,ATP6V1C1,ATP2B1,ABCD4,ABCG1,ABCC1 |
| 3.307e-03 | -5.71 | ST_JNK_MAPK_PATHWAY | MSigDB lists | ST_JNK_MAPK_PATHWAY | 40 | 13 | 17758 | 2588 |
MAP3K3,IL1R1,AKT1,MAP3K11,TP53,MAP3K9,DUSP10,DUSP4,MAP3K7,MAP3K5,MAPK7,GAB1,NR2C2 |
| 3.307e-03 | -5.71 | BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN | 40 | 13 | 17758 | 2588 |
GCLM,TRIM2,CYP4F11,LAP3,GCLC,SLC39A8,CTSB,AIM1,ABCB1,BTN3A2,BLCAP,KLF9,SPSB1 |
| 3.309e-03 | -5.71 | AMIT_EGF_RESPONSE_480_HELA | MSigDB lists | AMIT_EGF_RESPONSE_480_HELA | 157 | 36 | 17758 | 2588 |
LAMP1,BIN1,AGRN,SERPINE2,TUBB4B,DHPS,ITGA6,EFHD2,CYB561,SORBS3,BCL2L1,CCND1,ZYX,VASP,CTNNB1,RRBP1,TNFRSF12A,TACSTD2,TMEM8A,NFKB2,PPIF,MBP,PLAUR,CDYL,FXR2,DUSP4,ITPR3,EGFR,BCAR3,TNS4,PTPRF,OSMR,HMGA1,USF2,EHD1,EGLN1 |
| 3.311e-03 | -5.71 | V$HSF1_01 | MSigDB lists | V$HSF1_01 | 252 | 53 | 17758 | 2588 |
IER5L,ST13,CCM2,CACNA2D2,GATA3,EGR3,ISYNA1,MORF4L2,OSR2,VASH1,TNFRSF19,BCAP31,SIX4,ZNF212,IRF2BPL,ZFX,RNF220,BCL6,SRP54,ABCD1,KANK2,KNTC1,PIM1,PIKFYVE,GAD1,RIMS2,SOCS5,DUSP1,ADAMTS2,TGIF1,LAP3,DENND1B,BCL9,LHFPL2,PNKD,FOS,PLEKHB1,GIGYF1,RASGRP2,FOXD2,CACHD1,MAP2,SCG2,DBI,NETO2,NR4A3,FHL1,HSPB1,CMTM4,ACOT7,HS6ST3,EHD1,NR2C2 |
| 3.320e-03 | -5.71 | HSPE1 (heat shock 10kDa protein 1) | protein interactions | 3336 | 115 | 30 | 16036 | 2547 |
PPIF,CASP3,LASP1,SOD1,SHMT1,ALDH2,TXN,ENO2,UGP2,ALDH6A1,DSTN,SAT1,SOD2,EZR,GLO1,SPR,IDH1,VCP,PLS3,RCN1,DCK,DBI,AKR1B1,TLE1,PGM2L1,GOT1,TAGLN2,LRIF1,CTH,GPX4 |
| 3.320e-03 | -5.71 | SPRY2 (sprouty RTK signaling antagonist 2) | protein interactions | 10253 | 115 | 30 | 16036 | 2547 |
TCAF1,LASP1,PLSCR1,VANGL1,TESK1,CTSB,TRAF2,UBASH3B,CRIP2,GNE,PLS1,CBL,ADAMTSL4,NUBP1,EGFR,SH3KBP1,C19orf66,ZFP36,UBE2D2,DNM2,CAB39,SPRY4,HEXIM2,FAM219A,EGLN3,FAIM,SPRY2,FRS3,EGLN1,MDFI |
| 3.326e-03 | -5.71 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent | biological process | GO:0002486 | 3 | 3 | 16441 | 2455 |
HLA-B,HLA-C,HLA-A |
| 3.326e-03 | -5.71 | Peyer's patch morphogenesis | biological process | GO:0061146 | 3 | 3 | 16441 | 2455 |
ARTN,FOXL1,RET |
| 3.326e-03 | -5.71 | courtship behavior | biological process | GO:0007619 | 3 | 3 | 16441 | 2455 |
THRB,THRA,HEXB |
| 3.326e-03 | -5.71 | somatic muscle development | biological process | GO:0007525 | 3 | 3 | 16441 | 2455 |
NEB,NKD1,PPP2R3A |
| 3.326e-03 | -5.71 | embryonic skeletal limb joint morphogenesis | biological process | GO:0036023 | 3 | 3 | 16441 | 2455 |
OSR2,CTNNB1,OSR1 |
| 3.326e-03 | -5.71 | limb joint morphogenesis | biological process | GO:0036022 | 3 | 3 | 16441 | 2455 |
OSR2,CTNNB1,OSR1 |
| 3.326e-03 | -5.71 | epithelial cell differentiation involved in embryonic placenta development | biological process | GO:0060671 | 3 | 3 | 16441 | 2455 |
GRHL2,ST14,SPINT2 |
| 3.326e-03 | -5.71 | negative regulation of helicase activity | biological process | GO:0051097 | 3 | 3 | 16441 | 2455 |
SIRT1,IFIT1,TP53 |
| 3.326e-03 | -5.71 | negative regulation of peroxisome proliferator activated receptor signaling pathway | biological process | GO:0035359 | 3 | 3 | 16441 | 2455 |
TWIST1,ASXL1,PLIN5 |
| 3.326e-03 | -5.71 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle | biological process | GO:0071930 | 3 | 3 | 16441 | 2455 |
E2F7,RB1,E2F1 |
| 3.326e-03 | -5.71 | establishment or maintenance of microtubule cytoskeleton polarity | biological process | GO:0030951 | 3 | 3 | 16441 | 2455 |
KIF2C,LMNA,CKAP5 |
| 3.326e-03 | -5.71 | epithelial cell morphogenesis involved in placental branching | biological process | GO:0060672 | 3 | 3 | 16441 | 2455 |
GRHL2,ST14,SPINT2 |
| 3.327e-03 | -5.71 | OLSSON_E2F3_TARGETS_UP | MSigDB lists | OLSSON_E2F3_TARGETS_UP | 27 | 10 | 17758 | 2588 |
CASP7,FAM46A,TM9SF2,FAM102A,C1orf198,ECE1,AKNA,DAG1,TMPRSS4,ELF3 |
| 3.327e-03 | -5.71 | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | MSigDB lists | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | 27 | 10 | 17758 | 2588 |
PLA2G4A,ETV5,TFAP2A,SOX8,IQGAP3,RAB27B,DUSP4,GAD1,TRIM7,IFI6 |
| 3.327e-03 | -5.71 | WOTTON_RUNX_TARGETS_DN | MSigDB lists | WOTTON_RUNX_TARGETS_DN | 27 | 10 | 17758 | 2588 |
SIPA1L2,ADD3,ENO2,PLOD2,NR3C1,EGLN3,FNDC3A,ALCAM,SGPP1,XDH |
| 3.330e-03 | -5.70 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_UP | 179 | 40 | 17758 | 2588 |
GSDMD,SLC25A24,PAX6,CDH22,LRP4,PTTG1,ERI2,TESK2,RASGRP3,LGALS3BP,SH2D4A,CCDC92,RCN1,TFAP4,ZFX,BTG3,INPP5E,RUNDC3B,MAP3K9,KCNS3,TMEM8A,SCARA3,MAST4,FARP2,B9D2,PFKFB2,KIAA0040,SYBU,SHARPIN,GRIN1,GGH,AMZ2,GALNT3,PVRL2,C1orf21,RAB11FIP1,PRDM5,TRAF5,ARNT,PKIA |
| 3.330e-03 | -5.70 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | 179 | 40 | 17758 | 2588 |
DDX58,KIF3C,SLC35D2,SORT1,NQO1,TRIM5,SERPINB9,EPS8,IL13RA1,GDF15,TRIB2,PHLDA1,DDR1,IL17RB,ZFYVE16,RB1,ADD3,CYP1A1,CA2,DRAM1,ACTA2,NFKB2,FAR2,P2RX4,PRSS23,SERTAD3,BNIP3L,CALCRL,DGKE,FZD7,OPTN,MAGED2,PLCG1,HLF,H1F0,IRF7,F2RL1,HSPB1,AHR,PRKAR1A |
| 3.330e-03 | -5.70 | GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_UP | 179 | 40 | 17758 | 2588 |
CCNE2,CPT2,EGR3,FAM101B,BMP2K,APPBP2,SGPL1,TM9SF2,TIMP1,EFR3A,MTMR10,ZNF230,RP2,MINPP1,CPD,SEC23A,PHF20L1,UFD1L,BAG4,ERLEC1,NR3C1,DBR1,LITAF,MRPS18A,SLC17A5,PCTP,SPAG1,ARF4,C18orf8,DCAF10,TMEM50B,SLC9A6,DCUN1D1,AURKA,DHTKD1,PPP2R3C,ALG2,C1orf43,LRRC57,DLAT |
| 3.335e-03 | -5.70 | ependymoma_Grade_III-IV | COSMIC cancer mutations | ependymoma_Grade_III-IV | 19 | 8 | 17775 | 2585 |
TSC1,RB1,NF2,CTNNB1,AKT1,PTEN,TP53,IDH1 |
| 3.335e-03 | -5.70 | malignant_adnexal_tumour | COSMIC cancer mutations | malignant_adnexal_tumour | 19 | 8 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 3.336e-03 | -5.70 | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP | MSigDB lists | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP | 275 | 57 | 17758 | 2588 |
GRN,PLEKHG3,GSDMD,CMAS,DLGAP5,NDRG1,SLC25A13,ASL,STRN4,UBE2Z,CBLL1,MICALL2,GNB2,KTN1,RSAD1,TSEN34,CYHR1,ITGA3,XYLT2,DDHD2,FUT1,BAX,GYS1,ASH2L,CNPY3,CASD1,EEF1D,FAM134C,KDELR1,UPF3A,SPATA20,DOCK4,SYPL1,ORAI2,OPLAH,PHF20L1,BAG4,PQLC3,TCFL5,SHARPIN,PARP4,COX11,ARFRP1,SCRIB,PCTP,C18orf8,ARHGAP35,OSBPL2,EPN3,NUCB1,HLF,MPP2,FAM117A,TMEM8B,PLOD3,PPP2R5D,DMPK |
| 3.361e-03 | -5.70 | thyroid-other-neoplasm | COSMIC cancer mutations | thyroid-other-neoplasm | 8018 | 1230 | 17775 | 2585 |
HECA,PNPLA2,HEXB,RET,MCOLN3,TRAPPC8,BAIAP3,LACTB2,SPSB1,CARD10,LTBP3,SLC35E4,GRM5,ZNF275,LYPD5,MUC4,ATP13A3,DNM2,CLDN4,TIAM1,TIPARP,ANKRD9,MGAT5,DNAAF3,CCDC74A,NEK4,FBXL16,PRKAR2B,ENPP1,CARHSP1,PLCG1,MPRIP,CELF5,ATP7B,TRAF3IP1,FAM114A1,NOD2,RNASEL,STARD13,NXT2,SCN5A,ITGA6,ARHGEF35,GPSM2,CCDC64B,FAM21C,HPCAL4,RABGGTA,ATG4A,FLII,SH3D21,RAC2,FRY,MEGF8,FLRT3,FBXL14,PCYOX1,MAP3K9,USP38,ALPK1,PANX2,CNGA1,MAPK7,MOXD1,ULBP2,DGKG,KANK3,PPP6R1,TTLL1,HPS3,SHARPIN,KIF20B,ELK1,NPHP3,DPYSL4,PCTP,GNA11,PLIN5,C11orf45,IL1R1,SLC4A4,ETS2,RAET1L,S100A5,OSCP1,TMEM173,ADAMTS16,DOCK9,DMPK,TPRN,RNF224,RHBDL3,GRK6,MOCS1,KIAA1147,RBM23,ST5,MUC16,CDH1,SH3BP1,XYLT2,ENPP5,LRP11,ZNF365,MYT1,MX1,TMCC2,SNX8,ERMP1,COL6A2,C6orf1,APOBEC3D,AGPS,TANC1,ZNF618,TRIM7,EBF2,GIGYF1,SHROOM3,WFS1,AXL,PNPLA6,FAM149A,DMWD,ISOC1,MAPK12,GCAT,TRAF2,SDC4,HABP4,FLOT1,BTN3A1,ZNF219,SLC25A45,FUT2,IGSF9,KNDC1,CST3,TUBGCP6,KLC3,RAG1,CASD1,PARP9,ADAMTS2,TACC1,PIK3R1,NUB1,MRS2,PGBD1,AK4,CNTNAP1,RAB11FIP2,SYT7,PLA2G15,ITGAV,CMPK2,CD81,ACOT7,PHC1,TMEM131,ILDR1,TNK1,KIAA1462,EPAS1,ARFGEF1,PHOSPHO1,NDRG2,DNAJB11,ITPR2,MGAT5B,SPTB,FANCI,PLS3,SUSD2,CPNE2,INPP5E,RPS6KA2,NUP210,CTNNB1,RABEP2,PAPSS1,TMEM143,ABCA2,PLK1,KRT80,THRB,PTPN18,CELSR2,CR2,CCBL2,CKAP2L,ARFRP1,EAF2,SESN1,DZIP1L,TNS4,HS6ST1,PI4K2B,PLEKHG6,KCNMB4,AGPAT2,HOXA9,ARRDC1,KLF11,KPNA2,RMND5A,RUNX2,USH1C,LGALS3,HJURP,DNAJB2,RASA2,PDCL,SORBS3,ADCK5,HES2,RSAD1,ANO1,B4GALNT1,TNS3,RINL,FRAS1,ICAM5,SLC30A6,FCHO1,AHCY,FAR2,CKAP4,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,RGMB,ZNF320,SCRIB,ZSCAN12,PRX,FOXD2,RASGRP2,FA2H,COL13A1,SLC2A6,NLRC5,ZDHHC7,ZDBF2,PLD1,AKIP1,USP43,HOXB7,TP53,P2RX7,RHPN2,BAHD1,STIL,PCBP1,SYTL2,PDGFA,TACC2,BCL6,CDH3,VAT1,ESPN,NOTCH3,OAS3,CTDSP2,SULF2,PPIF,CLCN3,AKT1,KIAA0040,PTGER4,ACO1,DAG1,ATP13A2,ZNF628,RBL1,ABHD12,MMP17,STK38,MAOA,XRCC3,IRF7,SYT13,ARHGAP4,BTBD6,ST3GAL1,CTDSP1,BIN1,PINK1,CDH22,SCD5,GNAL,MCTP2,GTF3A,GDF15,AIP,LBR,IL22RA1,PARM1,VPS26A,DNAJB9,SH2D4A,NRP2,M6PR,ALPP,FAM63A,TFAP2A,SYK,GCNT1,LRRC24,WBP5,NFE2L3,P2RX4,HES1,GUSB,PLAUR,CRIP2,DPP9,MAML2,GGH,COL7A1,RNPEP,TXNDC11,BCL10,USP6,CNOT2,SMTNL2,NEIL3,ICOSLG,GOLGB1,FAM171B,SSH1,HSPG2,LGR4,VANGL1,TMEM86B,PSME1,NANS,VASH1,PJA2,OAT,PICK1,SLC9A7,ASPHD2,PAK6,TYMP,CYP1A1,ANKS6,FOSB,POLL,SERINC2,PIK3CA,SPATA18,CDYL,KIF13A,POR,ANKRD10,SH2D3C,LRIG1,PRDM5,BMP1,NFKBIZ,MAPK13,F2RL1,FGD1,SEMA6B,MRC2,CDKN1C,DHPS,TBC1D1,PRKAA1,TNFRSF19,PDXDC1,SH3RF2,DOPEY2,LYPD3,ZNRF2,BHLHE41,VASN,AIM1,DAPK1,ADCK2,CACNA1D,DLX4,KCTD3,GPR161,SOCS5,TRAK2,PIGC,SPATA20,PRODH,KCNJ12,KLK5,CEP89,ADCK3,DCHS1,PYGL,ATP8B3,ANTXR1,PDE11A,SLCO4A1,PLEKHH2,TJP3,FAAH,C1orf21,AGBL5,ARAP1,FAM83D,MPP2,KLK7,CABIN1,PER3,PLIN3,HOOK1,IFIH1,MFSD3,KIF3C,SPRED1,FOXO6,TCF25,TCTN2,CAPN12,ST14,DDIT4L,CCDC110,NDRG1,ATP2C2,TMEM170B,FLT3,DDR1,EPS8L2,EPM2A,APOBEC3B,C11orf84,NOV,TRANK1,RNASEH2A,EPHB4,OSBPL7,ATG4D,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,KIF1C,PKMYT1,PYGO1,B3GALNT2,ITPR3,ALCAM,ATP10D,FZD7,ZMPSTE24,AMZ2,DDOST,ACAD10,HAGHL,TRIOBP,FAM195A,SLC27A3,PRR15,COBL,MAMDC2,HAPLN3,CENPI,NES,PLD2,DNAH3,HLA-A,WWP2,CKAP5,E2F7,TMEM87B,FJX1,CITED2,SLC16A5,MSH6,FARP2,ALDH2,ARHGEF28,ZC3H11A,TMEM221,ZKSCAN2,DIAPH2,C2orf69,UBAC1,FOS,ACADSB,DGCR2,SEC14L4,FGFR2,TBX18,RIN3,ABCB1,ERAP1,WDR62,WDR91,FZD5,ESPL1,CXorf56,MELK,RGMA,UGT8,UBE2Q1,VARS2,MAP1LC3B,ERP29,HTR1D,ADPRHL1,SIPA1L2,HSF2,METTL7A,ARHGEF37,SIVA1,CEP78,ASH2L,CTTN,MYRIP,BTBD3,SP5,STK35,LAMP3,CYP1B1,CXXC5,LAP3,ASXL1,ITCH,RGAG1,TYSND1,MAN2A2,GPRC5B,MADD,TDRD7,SH3GLB2,ZNF165,CHPT1,LASP1,ARAP3,SERPINE2,ZNF395,PM20D2,FAM81A,ADAMTSL4,DUSP5,QSOX2,NOXA1,FAM20C,PFKL,COL6A1,MTMR10,LIMCH1,BRAT1,HLA-C,C10orf54,ZRANB1,ETV7,SNED1,TPGS2,PODXL2,KIAA1109,PRRC1,PDIK1L,MFSD7,RANBP9,RHPN1,INSR,TMEM30A,SH3BP4,NXPH4,DONSON,SHROOM2,JAK3,COL16A1,AFAP1,LMO7,NCKAP5,DYNLRB1,HDAC11,COL18A1,IL27RA,MRAS,PHLDA1,KCTD9,ZNF687,ARTN,CYP4F11,KIF14,ECE1,NFKB2,ETHE1,UPF3A,RFK,PTPRU,PDHX,ARHGAP35,SECTM1,SPTBN5,MAD2L1BP,ABCA1,LNP1,GLIS3,FBLIM1,ENO2,ARHGEF11,ARHGEF7,COL4A5,INTS8,NTAN1,SBF1,HDAC9,SYDE2,TOP2A,MZT2A,CARD8,TAF1B,LLGL2,A4GALT,BMP7,RRBP1,ARVCF,CLIP2,RPGR,MYO5A,DCAF6,WNT10B,RUNX3,LEPR,ENDOD1,CD8A,TRIM69,SPINT2,CSGALNACT1,ARRB1,GRAMD1C,ZMIZ1,PLOD3,AHR,RAB3IL1,ABCG1,NGEF,ACACB,KLK10,TRIM24,IL15RA,CACNA2D2,NRG2,LGI3,KIF26A,BARD1,PHF1,EPDR1,DAPK2,CALM2,WEE1,ZYX,RGS12,ARHGAP42,KIAA1107,DNAH6,CYP2S1,ALDH1A3,RDH14,SLC46A1,TUBG1,ACOX2,PIK3CD,TINAGL1,SEMA3G,ODF2L,SMARCA2,SPEF2,NWD1,MTRF1L,LOXL2,F12,PPP1R14C,MYOM1,CYP4F3,COL12A1,PGF,CAMK2N2,WDR11,GRID2IP,ANKRD6,DNM1L,LIMK1,MYLK,MAP3K11,SERPINB6,E2F8,GAB1,PDPR,SOX9,ZNRF3,MERTK,LMNA,ELF3,FAM189A1,CD22,PRICKLE4,ZIC5,STT3B,EPHX1,NAGPA,SLC37A1,SALL4,STAT4,MYBL2,PLS1,MEST,DCP2,PTPRF,NCOA3,HTT,ITPR1,DYSF,AURKA,DRP2,EGLN1,XDH,PAPSS2,ACTR8,FAM131C,WDTC1,PKP2,PRSS22,APC2,CCND1,SCNN1A,SCN3A,CAMSAP3,PSRC1,CYS1,SYNE2,CDCA2,RAB38,IRS2,SIPA1L1,PLEKHG1,INPP4B,PDXK,TTC8,TAOK2,TNRC6C,FARP1,RASSF7,PDIA3,ANO9,PKN1,NUCB2,KCNC4,HOXB2,TSPAN17,NEO1,CAPN2,DTX3L,CXCL16,ANK1,ADD3,IRAK1,ANKS1B,CALD1,FDXR,ADAM15,WWP1,MAPK11,NPTXR,ITM2C,CRTAP,HCN3,AMOTL2,NUDT8,LCA5,FMN1,RAPGEF2,MFSD2B,GRIN1,MYEOV,PLEKHA7,BLVRA,FAM109A,CRISPLD2,ABLIM2,TXK,PITX2,ATXN7L3,CCDC6,ZFP30,ARFGAP3,CENPE,CYBRD1,UNKL,SIGIRR,TRIM2,AGRN,GNPDA1,EPHA4,FHDC1,MCCC1,TP53I11,CDIPT,HDAC6,NUP62CL,LMAN2L,MKRN3,TNFRSF18,PXMP4,TLN2,TRAM1,S100A13,NEB,DDX59,CCDC38,ZNF462,ING1,CITED4,C12orf65,EZR,ERP44,ESYT1,PRKRA,ANLN,IDH1,IRX3,CDCA4,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,CTNND1,PIK3C2B,TTC9,PIEZO1,GLCCI1,PRKAA2,HLA-F,CNTNAP2,B4GALT4,DOCK11,SSX2IP,CORO1B,BMP2,RB1,VASP,DAZAP1,GATA2,TMEM8A,PLCB2,CYP26B1,CHSY3,WDR72,CORO2A,SPATA13,TCF7,EIF2AK1,UNC45B,MAPKAPK2,ITGA7,PRPS2,CTBP1,RNF146,AVPI1,UPF3B,XYLT1,ERBB2,LPIN3,SDF4,N4BP3,PLCG2,LHX6,MINPP1,DVL2,CTH,SIRT1,TMTC1,CDC20,MYPOP,DUOX1,PRRT4,RTN4RL1,PTK7,PSMD3,ADAMTS14,ANXA9,AIFM3,NDST3,ZC3HC1,GSDMD,MAN2B2,COL9A3,GOLIM4,PACSIN2,MACC1,PSMD10,JAG2,SIRPA,GBX2,ABCD1,SLC45A3,IGDCC4,DLGAP1,PSMB4,AMFR,PPARA,CAPNS1,AKAP3,BCAR1,MAPK8IP1,FUCA1,BANK1,FAT4,SERPINA1,NMI,PKD2,TBC1D4,UBE2C,NDFIP1,DIS3L,SUN1,GAA,KLC2,TAP1,PPFIBP2,GATA3,PLXNA1,CCNB1,FAM101B,IQCE,RGS3,IL31RA,ATRNL1,MTMR11,XKR8,LAMP2,LOC81691,TMEM68,KIFC2,SNTB2,HSPA12A,CASP9,NBPF3,TNS1,GALNT7,AURKB,MCFD2,SLC25A5,ZFAND5,SPNS3,ARHGEF26,SGPP1,AHRR,KDSR,SLC25A4,AREG,PLK2,TBX1,GNPTAB,FAM110C,DHTKD1,TMEM8B,UNC5B,RTN3,LZTS1,DLAT,KLF2,INPPL1,FRMD4A,HLA-E,DGKQ,ADO,C6orf106,NOTCH2,KIAA1161,BMP2K,MECOM,ITGA3,SNX18,PIK3AP1,SLC16A6,RUNDC3B,SORL1,TNFRSF12A,CD70,PIKFYVE,RIMS2,EEF1D,IGSF3,EPB41L5,QSOX1,MMD,MFI2,TBC1D8B,AMER1,PTPRH,ANO6,PIP4K2C,VEZT,FBXO10,RASA1,FRMD4B,DGKH,GABRD,PRKAG2,DCK,NAB2,SLC4A3,FGD6,PCDH19,NR4A2,MAP3K5,IRF1,PKD1L2,FRMPD3,PLEKHG3,CEP70,NLRX1,RPS6KA1,BROX,IRX4,AIFM2,NUDT12,MNS1,CYHR1,FAM46A,CDKN1B,CNNM4,LGMN,TMBIM1,TBC1D10B,GPX4,MYO5B,SEC23A,TMEM43,CAPN6,TEP1,SLC11A2,PRKCQ,C15orf39,AKR1E2,ZNF469,NIN,PRDM11,EPHA10,FYN,JAK1,KIAA1804,NRG1,HS3ST3B1,ATMIN,DENND5B,MRPS9,WASF3,ANKRD13D,PCOLCE,JRKL,SLC16A14,APOBEC3H,CYB561,SEPP1,PNPLA5,LGALS3BP,TEAD3,SIX4,TMCC3,PTEN,CENPJ,CNPY3,SPRY2,TRIM62,OSGIN1,NCOA2,RASGRF1,SHMT1,PARP4,FURIN,LRRC1,GPLD1,NUCB1,CTNS,PGM2L1,SERPINB5,GRIN2D,ETAA1,NCAPG2,ARSB,ESYT2,USP16,JARID2,EXPH5,EMX1,HEBP1,EPHX4,TAF6L,KIF2C,KREMEN1,DENND2D,PTCHD4,TSEN34,ABCD4,CHPF,ARHGEF10L,IMPAD1,DLG1,POF1B,ANKRD12,RAB20,RP2,MYH14,TECR,PTPRE,TDP1,ASCL5,SYNE3,RNF165,ROR1,PTGFRN,STK17B,TCN2,SEC14L2,MDK,ARHGEF19,FASTKD1,DHRS13,IARS2,CCDC74B,ADIPOR1,RAP1GAP,PPP2R5D,CPPED1,GRN,LRRFIP2,PEX6,SAMD9,PHLPP1,LYSMD4,AIM1L,OTUD1,ZNF432,LRRN2,KCNN4,EBF4,FXYD5,RFX5,KNTC1,NCEH1,ALS2CL,KDELR1,PARD3B,GYLTL1B,BTN3A2,AMDHD1,EGFR,FECH,GNAS,SLC6A6,CGREF1,NFKBIA,RHOBTB2,ALPK3,KIF12,FBXW5,GAS2L1,SLC25A24,ZSWIM5,ABCG4,GMPR,MICALL2,SETDB2,KHNYN,FRYL,ZDHHC12,SMO,RPN2,APIP,PDIA6,LOXL1,F2R,MAP3K3,SUSD3,ZNF525,TAF5,BAG4,KREMEN2,IGSF8,ERBB2IP,DOCK5,BHLHB9,PEX2,CANT1,VSIG10,PLXND1,AKNA,REEP4,CBX4,CDS2,SORT1,FRMD6,LRP4,FAM134A,MIER3,AES,FAM167A,SAC3D1,ZNF212,IRF2BPL,IL17RB,MDM1,MLPH,ADORA1,GALNS,KIAA0319,TRIM3,IQGAP3,SUN2,PHLDB3,NR4A1,OGDHL,MPV17L2,SPAG1,MAP1B,KLHL2,HLA-B,C2orf70,GLB1,HOXB13,SOX8,L1CAM,SNPH |
| 3.368e-03 | -5.69 | JAK2 (Janus kinase 2) | protein interactions | 3717 | 120 | 31 | 16036 | 2547 |
HES1,UBASH3B,CALM1,PIK3R1,ERBB2,TEC,YES1,LEPR,EGFR,VCP,SIRPA,SOCS3,IRS2,DTX3L,MDK,RCN1,PLCG1,FYN,INSR,PPP2R5A,IGF1R,IL6ST,PLCG2,PPP2R4,NFKBIA,STAT1,OSMR,CDKN1B,ERBB3,MAP3K5,JAK3 |
| 3.375e-03 | -5.69 | regulation of body fluid levels | biological process | GO:0050878 | 666 | 125 | 16441 | 2455 |
PLA2G4A,MYL9,KIF3C,PAPSS2,INPP5D,KLC2,TP53,DGKA,GATA3,F11R,ITPR2,KIF2C,PRKACA,KIF26A,DDR1,PDGFB,EMP2,TP73,PDGFA,CALM2,CCND1,WEE1,SCNN1A,STIM1,CYP4F11,PLCG2,PIK3CA,CLDN4,TRPC1,IRF2,KIF22,LMAN1,F2R,RASGRP1,TUBA4A,MYO5B,LAMP2,ENPP4,SOD1,CELSR2,AKT1,PRKAR2B,PRKCQ,F12,ATP1B1,CD40,ITPR3,MYL12A,PLCG1,FYN,KCNMB4,ABHD12,AXL,WFS1,ATP7B,HDAC1,HSPB1,F2RL1,MAFF,PRKAR1A,SERPINE2,CD63,ITGA6,DGKQ,HABP4,SELL,CALM3,KIF23,RACGAP1,DOCK11,FBLN1,MERTK,ITGA2B,FZD6,SIRPA,RAC2,ITGA3,TIMP1,ADORA1,GATA2,KCNN4,CD9,PRKG1,AK3,WNT3A,DGKG,SYK,ATP2B1,RHOA,PLSCR1,PLAUR,CALM1,ANO6,PIK3R1,VAMP3,HMG20B,C1GALT1C1,PDE5A,YES1,ILK,BCAR1,KIF11,GNA11,RHOB,DGKE,PDE11A,RASGRP2,DGKH,GNAS,SERPINA1,RAB11FIP2,PRCP,ITPR1,ARRB1,CENPE,ITGAV,ATP1B3,USF2,CBX5,TRPC3,L1CAM,DOCK9,IRF1,EHD1,XDH |
| 3.379e-03 | -5.69 | activation of MAPK activity | biological process | GO:0000187 | 143 | 34 | 16441 | 2455 |
AVPI1,TAB3,PRKAA1,P2RX7,PKN1,ERP29,DUSP5,TP73,BMP2,IRAK1,MAP3K9,DAB2IP,MAPK11,MDFIC,IQGAP3,MAP3K7,SYK,MDFI,SOD1,RIPK2,MAPKAPK3,MAP3K6,CDK1,MAPKAPK2,INSR,MADD,MAP3K11,NOD2,KIAA1804,ARRB1,EFNA1,MAP3K5,CD81,GAB1 |
| 3.380e-03 | -5.69 | KAMIKUBO_MYELOID_MN1_NETWORK | MSigDB lists | KAMIKUBO_MYELOID_MN1_NETWORK | 19 | 8 | 17758 | 2588 |
GAS2L1,RECQL,RGS12,CRIP2,PGRMC1,SGK1,TGFBR1,NCKAP1 |
| 3.380e-03 | -5.69 | KIM_MYCL1_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYCL1_AMPLIFICATION_TARGETS_DN | 19 | 8 | 17758 | 2588 |
GRHL2,VANGL1,PHTF1,RHPN2,UACA,OAT,ANLN,CMTM6 |
| 3.380e-03 | -5.69 | REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 19 | 8 | 17758 | 2588 |
TSC1,ARAP3,RALBP1,ARAP1,FGD6,NOTCH2,ARF6,FGD1 |
| 3.380e-03 | -5.69 | AMIT_EGF_RESPONSE_40_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_40_MCF10A | 19 | 8 | 17758 | 2588 |
GNS,UNC93B1,CYR61,ZFP36,BUB1,EGR3,FOS,DUSP5 |
| 3.380e-03 | -5.69 | NIELSEN_LEIOMYOSARCOMA_CNN1_UP | MSigDB lists | NIELSEN_LEIOMYOSARCOMA_CNN1_UP | 19 | 8 | 17758 | 2588 |
MYL9,LOC81691,SORBS1,MYLK,RAB23,ACTA2,GABRG2,RIMS2 |
| 3.380e-03 | -5.69 | RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 19 | 8 | 17758 | 2588 |
ARHGEF3,FARP1,RCBTB2,ARHGEF11,RAPGEF2,MADD,TIAM1,FARP2 |
| 3.380e-03 | -5.69 | BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_DN | MSigDB lists | BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_DN | 19 | 8 | 17758 | 2588 |
HES1,PAPSS2,SEC61G,ATP9A,SGCB,MYBL1,MPHOSPH9,SAC3D1 |
| 3.380e-03 | -5.69 | BIOCARTA_GCR_PATHWAY | MSigDB lists | BIOCARTA_GCR_PATHWAY | 19 | 8 | 17758 | 2588 |
GNAS,CALM2,AKT1,NR3C1,CALM1,PIK3R1,PIK3CA,CALM3 |
| 3.380e-03 | -5.69 | MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_UP | MSigDB lists | MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_UP | 19 | 8 | 17758 | 2588 |
WEE1,GATA2,NGFRAP1,CST3,ALG2,JAG2,COL16A1,FAH |
| 3.383e-03 | -5.69 | CAGCTG_V$AP4_Q5 | MSigDB lists | CAGCTG_V$AP4_Q5 | 1429 | 244 | 17758 | 2588 |
DOC2A,LTBP1,ACVR1,TXN,PPM1J,TSC22D3,SMARCAL1,ARFGEF1,GATA3,NRG2,LGI3,PLAC1,F11R,PLA2G16,SEPT4,PJA2,PDGFB,PHF1,CHPF,PLS3,CALM2,CDKN2C,PAK6,PQLC2,RGS12,STIM1,CASC4,CDKL5,CABP1,PASK,SLC44A1,MITF,POLL,KCNS3,ANKRD12,IQCD,TINAGL1,WBP4,TRAM1,BTBD3,NEB,TUBA4A,SMARCA2,KCNIP3,TRIM8,RGAG1,CBX6,TFAP2C,TNS1,PTGFRN,RNF19B,LHFPL2,ARF4,ABR,PGF,CXXC4,MDK,MPRIP,KLF12,NKD1,MYLK,BMP1,TMEM8B,SPRY4,APBA2,STARD13,RRAGD,PRKAA2,SCN5A,INPPL1,BMF,PARP12,ZCCHC24,ITGA6,FXYD3,ADO,ETV5,ATP6V1E2,CALM3,NDUFA4,SORBS3,APBA1,DHRS3,S100A2,TNFRSF19,PSIP1,SSX2IP,TFAP4,WDFY1,ITGA3,IGF1R,LRRN2,PIK3AP1,MEGF8,ATP5H,FLRT3,FRAS1,MTMR10,SRP54,USP1,ZRANB1,CTSD,SLC12A2,PLCB2,TSPAN33,PLEKHA6,CALM1,MYBL2,TCF7,TP53INP2,UNC45B,EPN3,INSR,H1F0,MFSD2A,AGBL5,DYSF,RHOBTB2,NXPH4,CDK18,EFNA1,MAP3K5,DRP2,HOOK1,TOB1,DOCK9,DMPK,CCNE2,SPRED1,NCKAP5,SORBS1,REPS2,NDRG1,DDIT4L,CAST,HDAC11,APOO,WDTC1,IRX4,MAPK4,BAHD1,SNN,PRKACA,DDR1,REPS1,GNB2,SYTL2,APPBP2,C1orf116,SRPX,SH3BP1,DACT1,LMO4,REEP1,BCL6,VAT1,CDH3,CDKN1B,ACSL4,RASGEF1A,MYT1,SULT2B1,LOXL1,DOCK4,MAP3K3,MBP,AKT1,NRBF2,PRKCQ,DUSP4,ITPR3,B3GALNT2,NFIX,PTK7,PSMD3,KLF5,NR3C2,ARNT,IER5L,TNRC6C,CPEB4,IGFBP6,GCAT,CDCA3,NES,ETS1,BEX2,NRP2,XPR1,PPP2R3A,HDAC9,IRF2BPL,ANK1,ADRBK1,ITGB8,PHF7,KCNK5,FAM63A,CD9,SLC44A2,ERBB3,RAG1,CITED2,GFI1,TRIM62,TPCN1,CAMK2G,DUSP1,DLGAP1,P2RX4,TGIF1,ADAMTS2,CASK,WNT10B,TACC1,NR4A1,TEF,CRIP2,VAMP3,PRICKLE1,DPP9,EMP3,RUNX3,COL7A1,SRRM3,AIF1L,MAPK8IP1,ARHGAP24,LEMD2,BTG1,E2F1,NR4A3,RYK,GRIN2D,LRRK1,GEM,OSR1,ZMIZ1,ATP6V1C1,SHOX2,L1CAM,FOXA1,ZBTB33,SNPH |
| 3.383e-03 | -5.69 | BNIP3L (BCL2/adenovirus E1B 19kDa interacting protein 3-like) | protein interactions | 665 | 33 | 12 | 16036 | 2547 |
CASK,GNB5,TP53,BNIP3L,STEAP3,BCL2L1,CAMK1D,MAP1LC3B,SMCO4,RHEB,GABARAPL1,ATP13A2 |
| 3.390e-03 | -5.69 | microtubule organizing center part | cellular component | GO:0044450 | 140 | 33 | 17570 | 2579 |
MZT1,POC1B,FLOT1,CNTROB,ZMYND10,STIL,SSX2IP,CKAP5,TOP2A,CCDC92,MZT2A,CENPJ,TUBGCP6,PLK4,CAPG,TUBG1,RP2,MPHOSPH9,CEP89,UXT,FOPNL,CCSAP,CCNF,NUBP1,DZIP1L,CEP162,NIN,HTT,PLK2,AURKA,CEP41,CFAP20,WDR62 |
| 3.394e-03 | -5.69 | CTSA (cathepsin A) | protein interactions | 5476 | 29 | 11 | 16036 | 2547 |
CTNNBIP1,LAMP2,PVRL4,CASP7,PLAUR,DNAJB2,CTSA,GLB1,FBXO6,OAT,CTSD |
| 3.394e-03 | -5.69 | MAPKAPK5 (mitogen-activated protein kinase-activated protein kinase 5) | protein interactions | 8550 | 29 | 11 | 16036 | 2547 |
MAPKAPK2,PLA2G4A,MBP,TP53,CDCA8,GYS1,MAPK11,MAPK4,MAPK13,HSPB1,MAPK12 |
| 3.394e-03 | -5.69 | B2M (beta-2-microglobulin) | protein interactions | 567 | 29 | 11 | 16036 | 2547 |
CALR,HLA-B,CD8A,TAPBP,PRSS23,HLA-E,HLA-F,PTTG1,TAP1,HLA-C,HLA-A |
| 3.394e-03 | -5.69 | S100B (S100 calcium binding protein B) | protein interactions | 6285 | 29 | 11 | 16036 | 2547 |
PGM1,TNIP1,S100A11,NDRG1,STK38,IQGAP1,S100A4,CALM1,TP53,S100A2,S100A6 |
| 3.410e-03 | -5.68 | platelet-derived growth factor receptor binding | molecular function | GO:0005161 | 15 | 7 | 16491 | 2452 |
PDGFA,IL1R1,PDGFC,TYMP,PTPRJ,PDGFB,PTEN |
| 3.413e-03 | -5.68 | MODULE_175 | MSigDB lists | MODULE_175 | 54 | 16 | 17758 | 2588 |
LTBP1,TNK1,IL15RA,TRIP10,COG2,CR2,COL18A1,PHLDA1,ZNF212,ARHGAP35,SNTA1,ANK1,IGF1R,PLOD2,SEMA4D,TAX1BP3 |
| 3.413e-03 | -5.68 | GENTILE_UV_RESPONSE_CLUSTER_D4 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D4 | 54 | 16 | 17758 | 2588 |
RAPGEF2,GNE,CCNB1,FZD7,PDCD10,UAP1,CTGF,GATA2,ZFP36,ATP13A3,TPST1,AURKA,KPNA2,USP1,ARF6,RAD21 |
| 3.413e-03 | -5.68 | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | MSigDB lists | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | 54 | 16 | 17758 | 2588 |
COL9A3,GCLC,PBX3,ROR1,VASH1,ABR,CDK14,FRY,KCNN4,DBI,SFMBT1,MAP3K5,APOBEC3G,ALDH3A2,CCDC88A,IGSF3 |
| 3.413e-03 | -5.68 | PID_TAP63_PATHWAY | MSigDB lists | PID_TAP63_PATHWAY | 54 | 16 | 17758 | 2588 |
PLK1,NQO1,SPATA18,ITCH,TFAP2C,GDF15,DHRS3,S100A2,TP53I3,FAS,ITGA3,FDXR,BAX,SERPINB5,WWP1,FLOT2 |
| 3.420e-03 | -5.68 | PI3K/AKT activation | REACTOME pathways | R-HSA-198203 | 101 | 26 | 8202 | 1235 |
TNRC6C,RHOA,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 3.422e-03 | -5.68 | CAV1 (caveolin 1) | protein interactions | 857 | 155 | 38 | 16036 | 2547 |
FAF2,TRAF2,STRN4,FLOT1,PDIA3,ERBB2,TGFBR1,PLD2,HDAC6,PRKACA,IRAK1,ADRBK1,CTNNB1,CDH1,PTEN,TRPC1,PPP1CA,FLOT2,F2R,ABCC1,UFD1L,RHOA,ITCH,ILK,ITPR3,CD40,DAG1,VCP,EGFR,FAS,PTPRF,PLCG1,PTGS2,FYN,INSR,PPP2R4,ABCB1,PLD1 |
| 3.429e-03 | -5.68 | lateral plasma membrane | cellular component | GO:0016328 | 49 | 15 | 17570 | 2579 |
SNTA1,EPCAM,SCN5A,CTNNB1,CDH1,VANGL1,BVES,IQGAP1,CORO1C,TBCD,DLG1,CLDN4,TACSTD2,ERBB3,IQGAP3 |
| 3.435e-03 | -5.67 | response to estradiol | biological process | GO:0032355 | 117 | 29 | 16441 | 2455 |
GRN,CASP3,NQO1,CASP9,PDGFB,ETS1,EGFR,SOCS3,MMP15,CALR,CCND1,NCOA3,PTGS2,CCNA2,CTNNB1,CTGF,AREG,PTEN,MAP2,BMP7,CST3,AURKA,CDKN1B,IGFBP2,GPER1,ARNT2,FOXA1,DRD1,DUSP1 |
| 3.436e-03 | -5.67 | Ras signaling pathway | KEGG pathways | hsa04014 | 227 | 51 | 6908 | 1076 |
PLA2G4A,RALBP1,RASA2,CALM3,RASGRP3,MRAS,PLD2,BCL2L1,PLA2G16,PDGFB,ETS1,PRKACA,GNB2,FGF19,CALM2,PDGFA,PAK6,RAC2,IGF1R,GNB5,SHC3,RALB,PLCG2,PAK2,PIK3CA,PIK3CD,TIAM1,RASGRP1,RASGRF1,PDGFC,RHOA,AKT1,PIK3R1,CALM1,GRIN1,ELK1,EGFR,RASA1,RASGRP2,PGF,PLCG1,INSR,ETS2,FGFR2,CSF1,FGF18,EFNA5,EFNA1,PLD1,ARF6,GAB1 |
| 3.441e-03 | -5.67 | GOLUB_ALL_VS_AML_DN | MSigDB lists | GOLUB_ALL_VS_AML_DN | 23 | 9 | 17758 | 2588 |
PPIF,ZYX,LGALS3,HOXA9,NFKBIA,CST3,CTSD,CD33,FAH |
| 3.441e-03 | -5.67 | BIOCARTA_CELLCYCLE_PATHWAY | MSigDB lists | BIOCARTA_CELLCYCLE_PATHWAY | 23 | 9 | 17758 | 2588 |
CCND1,CDKN2C,RB1,RBL1,E2F1,CDKN1B,CCNB1,CDKN2D,CDK1 |
| 3.441e-03 | -5.67 | BIOCARTA_RAS_PATHWAY | MSigDB lists | BIOCARTA_RAS_PATHWAY | 23 | 9 | 17758 | 2588 |
RHOA,AKT1,RALBP1,CASP9,PIK3R1,PIK3CA,PLD1,BCL2L1,ELK1 |
| 3.441e-03 | -5.67 | REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | MSigDB lists | REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 23 | 9 | 17758 | 2588 |
TSC1,ARAP3,RALBP1,ARAP1,FGD6,NOTCH2,ARF6,DMPK,FGD1 |
| 3.449e-03 | -5.67 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | 196 | 43 | 17758 | 2588 |
LTBP1,KLF2,KIF3C,NQO1,TRAF2,FAM134A,IL27RA,PHF1,KIAA1161,SGPL1,AKIRIN1,ST5,RPS6KA2,CA2,RALGPS2,SH3BP1,SORL1,ERCC2,NOTCH3,NAGA,HCN3,QSOX1,TIMP2,PLAUR,SLC11A2,TCF7,TANC1,FOS,GNA11,BSDC1,ULK2,MMP15,RPL12,COQ10A,NR1D2,NR4A3,CANT1,F2RL1,ST3GAL1,JARID2,PHC1,NGEF,ABCG1 |
| 3.449e-03 | -5.67 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | 196 | 43 | 17758 | 2588 |
GAS2L1,CCNI,ADD1,TBC1D1,DAP,TRAF2,HEXB,AES,NKRF,SEPP1,DHRS3,ERP29,AIP,TFAP4,RAC2,DOPEY2,SIVA1,LMO4,BDH1,CD9,ADAM15,TAX1BP3,CLIP2,TTPA,KDELR1,UPF3A,MLEC,ALDH2,ZWINT,TIMP2,S100A4,RNF11,FURIN,H2AFV,MAGED2,MAN2A2,GDE1,UBE2D2,PNPLA6,ZMIZ1,LTA4H,CBX7,PCSK5 |
| 3.449e-03 | -5.67 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 196 | 43 | 17758 | 2588 |
TXN,S100A11,GATA3,EFHD2,RACGAP1,FAM46C,IL18R1,FGF19,HLA-A,CAPN2,DAPK2,WEE1,PCNA,FOSB,SORL1,MDFIC,PIM1,TMEM37,CTSD,F2R,SNX10,S100A13,RPGR,S100A6,POU6F1,PLSCR1,SNTB2,S100A4,CRIP2,CAPNS1,GGH,YES1,CYFIP2,DOCK5,RNF19B,FOS,CASP4,NUCB1,H1F0,CHPT1,TOB1,ACOT7,XDH |
| 3.458e-03 | -5.67 | fat | COSMIC cancer mutations | fat | 120 | 29 | 17775 | 2585 |
SPEF2,SMARCA2,ARAP3,HSP90B1,AKT1,GRIK2,GNE,TP53,ERBB2,VARS2,CBL,IDH1,PDXDC1,SPTB,EGFR,PDE11A,CORO1B,GNAS,RB1,SS18,CTNNB1,CDH1,HTT,PTEN,LLGL2,ATP7B,PLK4,PIK3CA,PER3 |
| 3.468e-03 | -5.66 | RGAANNTTC_V$HSF1_01 | MSigDB lists | RGAANNTTC_V$HSF1_01 | 422 | 82 | 17758 | 2588 |
SLC2A4,ST13,ARMCX3,TRIP10,CACNA2D2,GATA3,EGR3,MORF4L2,OSR2,VASH1,BCAP31,CHST2,C1orf116,CYP1A1,SHC3,TSPAN6,LMAN2L,IL6ST,BCL6,RASGEF1A,LAP3,RGAG1,LHFPL2,PNKD,SP4,PLEKHB1,GIGYF1,POPDC3,MAP2,STARD13,HSPB1,CMTM4,HS6ST3,IER5L,CCM2,PSMD10,COL4A5,ISYNA1,SIX4,ZNF212,ATG4A,IRF2BPL,FOXP2,ZFX,DAPK1,CD9,SRP54,ADAM15,TSPAN13,WWP1,MDFIC,ABCD1,KNTC1,CACNA1D,PIKFYVE,GAD1,RIMS2,DUSP1,HES1,ADAMTS2,FBLN5,ELK3,WNT10B,DENND1B,BCL9,RASGRP2,GNAS,DCAF10,HLA-B,CACHD1,SCG2,COL13A1,DBI,NR4A3,NETO2,NR4A2,FHL1,ATP1B3,SEMA3A,ACOT7,IRF1,EHD1 |
| 3.489e-03 | -5.66 | human chr7q21.12 | chromosome location | human chr7q21.12 | 7 | 4 | 26250 | 2805 |
TMEM243,SLC25A40,ABCB1,RUNDC3B |
| 3.493e-03 | -5.66 | KRAS.DF.V1_UP | MSigDB lists | KRAS.DF.V1_UP | 185 | 41 | 17758 | 2588 |
ARHGEF3,DLGAP5,ATP9A,GNE,ETNK1,HERC5,BCL2L1,LTBP3,LGALS3BP,BMP2,RAC2,SRPX,DPYSL2,FLRT3,ALDH1A3,FUT8,BCL6,TRPC1,ALDH7A1,IFIT1,FAR2,HSPA2,SPRY2,DDB2,OPLAH,LOC81691,FADS2,ELK3,CDA,EMP3,LOXL2,AURKB,BORA,MAP3K6,STEAP1,TP53I3,NAT1,INPP4B,PLIN3,SERPINB1,E2F8 |
| 3.493e-03 | -5.66 | PROVENZANI_METASTASIS_UP | MSigDB lists | PROVENZANI_METASTASIS_UP | 185 | 41 | 17758 | 2588 |
LAMP1,PSMD7,LMCD1,GDF15,CENPN,CARD10,VPS26A,PDIA4,CDKN2C,TNS3,OXCT1,CES2,CTSC,BRD7,AKR1B1,CADPS2,BTBD3,SPRY2,TMED2,MCCC2,SGCE,ZWINT,SNTB2,SAT1,GALNT7,POLD3,BORA,CDK1,LCP1,PLEKHB1,PRIM1,BTG1,FYN,PROM1,RBM47,PRCP,LRIG1,PRKCDBP,LTA4H,TRAF5,ATMIN |
| 3.495e-03 | -5.66 | protein targeting to lysosome | biological process | GO:0006622 | 15 | 7 | 16441 | 2455 |
NAGPA,SNX16,SORL1,ZFYVE16,GCC2,SCARB2,GNPTAB |
| 3.495e-03 | -5.66 | regulation of epithelial cell differentiation involved in kidney development | biological process | GO:2000696 | 15 | 7 | 16441 | 2455 |
GATA3,PROM1,CTNNB1,OSR1,FAT4,WWTR1,STAT1 |
| 3.499e-03 | -5.66 | regulation of defense response | biological process | GO:0031347 | 757 | 140 | 16441 | 2455 |
LAMP1,UNC93B1,TRIM5,XIAP,LMCD1,TAP1,CUL1,GATA3,PSME1,IL18,ITPR2,ELMOD2,CALM2,ZYX,PHYHIP,PSMD1,AP1M2,RPS6KA2,IL6ST,TSPAN6,PSMC2,DUSP10,SCARA3,APOBEC3G,SMAGP,RASGRP1,CD55,TNIP1,ITCH,PBK,USP18,SLC35C1,F12,MYOM1,ABR,GPRC5B,TRAF3IP1,MYLK,NOD2,MAPK13,F2RL1,PSMC1,PPP2R5D,DDX58,HLA-E,PSMD7,CALM3,SLC1A3,ZCCHC17,PIK3AP1,PAK2,FAM13B,ALPK1,MAPK7,PSMA5,KLK5,MAPKAPK3,MICB,CALM1,SHARPIN,CALCRL,ELK1,PSMA4,MAPKAPK2,IL1R1,PVRL2,PELI2,ITPR1,NFKBIA,NLRC5,OSMR,MDH1,STK39,KLK7,IFIH1,RPS6KA3,TMEM173,IRF1,IL15,NLRX1,PSME2,RPS6KA1,SLC7A2,PRKACA,IER3,CD46,NOV,PLCG2,BCL6,IFIT1,LGMN,NFKB2,RIPK2,PTGER4,ATP1B1,ITPR3,DUSP4,CASP4,SOCS3,PTGS2,FYN,JAK1,CDK19,PSMD3,STAT1,IRF7,HSP90B1,TAB3,CTSB,SERPINB9,HERC5,PSMD10,GSTP1,ETS1,HLA-A,IRAK1,ADORA1,IL17RA,MAPK11,MAP3K7,CNPY3,SYK,PARP9,PSMB4,PLSCR1,VAMP3,PPARA,FXR2,FOS,TXK,BCL10,CTSL,HLA-B,NR1D2,SLC35B3,NMI,UBE2D2,ERAP1,GPER1,NDFIP1 |
| 3.501e-03 | -5.65 | keratan sulfate metabolic process | biological process | GO:0042339 | 35 | 12 | 16441 | 2455 |
GNS,B3GNT7,SLC35D2,B3GNT2,GALNS,HEXB,GLB1,B4GAT1,B4GALT4,B4GALT3,ST3GAL1,CHST2 |
| 3.510e-03 | -5.65 | spindle midzone | cellular component | GO:0051233 | 27 | 10 | 17570 | 2579 |
PLK1,KIF14,CDCA8,AURKA,KIF20B,RACGAP1,CTTN,CENPE,AURKB,GEM |
| 3.512e-03 | -5.65 | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_DN | 163 | 37 | 17758 | 2588 |
PINK1,AGRN,REPS2,WDTC1,IL13RA1,ECI1,MECOM,CTNNBIP1,PHYHIP,CES2,TACC2,SERINC2,SORL1,TWIST1,STEAP3,TACSTD2,ETHE1,CRTAP,CPD,ORAI2,TCEB2,LPGAT1,CRIP2,BNIP3L,GRIN1,FOXL1,AGPAT2,ACVRL1,RAB31,ADIPOR1,NRG1,FHL1,LTA4H,LZTS1,RTN3,CYBRD1,RRAGD |
| 3.514e-03 | -5.65 | brainstem | COSMIC cancer mutations | brainstem | 3233 | 520 | 17775 | 2585 |
FAM160B1,AASS,AK7,DNAJC3,RET,CACNA2D2,FBXO2,LACTB2,SNX9,ZNF275,CDKN2C,ARHGAP42,KIAA1107,DNAH6,CYP2S1,ATP13A3,TUBG1,CRY2,CPE,MGAT5,ERAP2,TNIP1,SH3BGRL,CDA,PRKAR2B,LOXL2,MYOM1,LCP1,WDR11,GRID2IP,ATP7B,TRAF3IP1,AGFG2,MRPS28,GAB1,SCN5A,ITGA6,ZNRF3,GPSM2,TTYH3,ELF3,FRY,FAM189A1,CD22,CADPS2,ALPK1,STT3B,NCAM1,MYLIP,ULBP2,C9orf72,MCCC2,SLC37A1,KIF20A,SALL4,FHL2,KIF20B,NPHP3,PCTP,SFXN5,PSMA4,GNA11,DCP2,CYB5A,PTPRF,CACHD1,HTT,ITPR1,CLMN,DYSF,RUSC1,MTM1,RNF224,FAM131C,C5orf30,RGS20,PKP2,MOCS1,REPS1,ZNF385B,RBM23,MUC16,CDH1,LRP11,ERMP1,NRBF2,SEPT6,SYNE2,XRCC6BP1,TANC1,EBF2,CCNB3,SHROOM3,TTC12,CORO1C,PRIMA1,MPZL1,FAM189A2,BACE1,TRAF2,BTN3A1,NUCB2,IFT27,ICAM1,ANK1,ITGB8,IGSF9,ANKS1B,FAM160A2,CALD1,MGAT4A,TUBGCP6,PLEKHF1,AK3,RAG1,CASD1,PARP9,PVRL4,ADAMTS2,LCA5,FAM160A1,RAPGEF2,PIK3R1,CXorf57,MYEOV,EMP3,SNTB1,SKA1,RGPD5,PLOD2,RAB11FIP2,ACVRL1,ITGAV,CYBRD1,TLL2,TMEM131,FAM199X,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,ITPR2,HDAC6,SPTB,PLS3,CTNNB1,NPNT,PAPSS1,SLC44A1,ELF5,NTN4,ANO4,NEB,ZNF462,THRB,MCTP1,CR2,ERP44,ESYT1,EAF2,PRKRA,IDH1,SESN1,RHEB,TNS4,HS6ST1,PI4K2B,KCNMB4,CDCA4,KLF12,EPB41L4A,HS6ST3,PARP12,UBASH3B,RACGAP1,CNTNAP2,DHRS3,FBLN1,MYO5C,TNS3,RB1,DAZAP1,IGF1R,FRAS1,AHCY,NTN1,MPHOSPH9,CKAP4,ABCC1,CHSY3,WDR72,PLEKHA6,CORO2A,ZNF320,RASGRP2,DHDH,CSF1,NLRC5,LTBP2,ZDBF2,SEMA3A,RAD21,TMX4,TP53,RHPN2,CYP26A1,CDK14,TTC21B,SRPX,EFR3A,TACC2,WDR44,NOTCH3,OAS3,FAR1,TMTC1,MBP,AKT1,ACO1,DNAJC10,PTPRJ,RBL1,ABHD12,PTK7,MAOA,CHMP4B,EFNA5,FAM134B,CMAS,GOLIM4,TRAPPC10,SCD5,MCTP2,GABRG2,SELL,HMGN3,LBR,IL22RA1,PPP2R3A,SLC9A2,NRP2,FZD6,ZDHHC21,LYPD6,UBE2J1,SLC35B4,CPLX1,KLF9,DLGAP1,HMMR,CRB3,NR3C1,AMFR,PPARA,DPP9,MAML2,DGKE,USP6,DDAH1,BANK1,TWSG1,ACADM,TBC1D4,FAM171B,ACVR1,ATP8A1,PPFIBP2,C1orf198,PDGFRL,PLXNA1,VASH1,SLC9A7,STIM1,PIK3CA,AOX1,ATRNL1,SLC35C1,TNS1,AURKB,GALNT7,LDB2,POR,ULK2,AHRR,RBM47,PRDM5,WBSCR27,DLAT,DDX58,MRC2,FRMD4A,SCOC,TBC1D1,SLC25A27,NOTCH2,SLC1A3,APBA1,TNFRSF19,PDXDC1,KIAA1161,DOPEY2,AIM1,TPST1,PRKG1,MSH2,SORL1,OSTF1,CACNA1D,KCTD3,EEF1D,IGSF3,GFPT1,DDB2,KLK5,TBC1D8B,CEP89,MICB,DCHS1,AMER1,PYGL,PKM,ANTXR1,NFIB,FBXO10,PDE11A,DGKH,MMP15,GABRD,NT5C2,SLCO4A1,DCK,PELI2,C1orf21,APPL2,PIAS2,PCDH19,CABIN1,PLIN3,HOOK1,PKD1L2,CAPN12,TCTN2,ST14,FTH1,APOBEC3B,RALB,OSBPL7,MYO5B,CAPN6,FOXJ2,TEP1,UTRN,TMEM144,PRKCQ,ASB13,ITPR3,CBL,ALCAM,CMTM7,ZMPSTE24,FYN,JAK1,SLC27A1,NRG1,ZC3H12B,B4GALT3,SLC27A3,NR3C2,COBL,MAMDC2,MRPS9,OTUD5,ARHGEF3,EPS8,PBX3,CYB561,DNAH3,CKAP5,WWP2,RNF128,PTEN,FUT8,SGK3,TAGLN2,MSH6,NCOA2,FARP2,PDGFC,B3GNT2,ARAP2,CASK,ERMAP,PAPD7,TCFL5,FURIN,DIAPH2,YES1,ACADSB,FGFR2,AMMECR1,ABCB1,CSTF2,WDR62,MELK,JARID2,ESYT2,LTBP1,UGT8,FAF2,UBE2Z,KIF2C,DNER,TMC1,KREMEN1,SH3KBP1,HTR1D,NKAIN3,HSF2,CDKL5,TSPAN6,DPYSL2,ANKFN1,DLG1,POF1B,MYH14,ARNT2,SLC39A10,TECR,MYRIP,IL1RAP,LAMP3,OLFML2A,ASXL1,SYNE3,ITCH,RNF165,ROR1,PTGFRN,EDNRA,FASTKD1,CAPN1,GRN,ELOVL7,PHLPP1,FAM81A,AIM1L,CA2,PRKCI,LIMCH1,KNTC1,GAD1,ALS2CL,SNX7,PODXL2,KIAA1109,HEATR5A,EGFR,BCAR3,GNAS,TSC1,UAP1,ALPK3,SHROOM2,RARG,COL16A1,SNX30,LMO7,NCKAP5,PDIA5,COL18A1,IL27RA,PHLDA1,EXT2,KCTD9,SMO,EPB41L4B,TAF5,C3orf52,TMTC2,DOCK5,PDHX,SECTM1,TLE1,LIFR,CBX4,KDELC2,ARHGEF11,SH3D19,POC1B,ARHGEF7,POMGNT1,TMEM63A,MDM1,MLPH,LLGL2,BMP7,KIAA0319,BRD7,IQGAP3,MYO5A,RAB3B,ADAM17,ASPM,PHLDB3,RC3H2,LRRC66,OGDHL,TTC7A,MAP1B,ENDOD1,KLHL2,HLA-B,SWAP70,ARRB1,OTUB2,ATP6V1C1,PLOD3,ZMIZ1,NGEF |
| 3.515e-03 | -5.65 | DOANE_RESPONSE_TO_ANDROGEN_UP | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_UP | 174 | 39 | 17758 | 2588 |
BCAM,FARP1,PINK1,LGALS3,JRKL,NDRG1,PDIA5,NENF,CNTNAP2,TAF6L,MICALL2,DNAH3,C1orf116,RND1,CALR,SNTA1,ZNF432,GNB5,ELMO2,BMP7,RRBP1,AHCY,FAR2,GM2A,MCCC2,ABCC1,CLCN3,PRKAR2B,ARHGDIB,FXR2,EAF2,ALCAM,SEC14L2,ENDOD1,TTC12,TMC5,ARRB1,PDXK,COBL |
| 3.535e-03 | -5.65 | V$IRF_Q6 | MSigDB lists | V$IRF_Q6 | 230 | 49 | 17758 | 2588 |
GSDMD,PARP12,CPEB4,KLHL13,ZCCHC24,HLA-F,ETV5,DGKA,SELL,PRKACA,PRR7,IL22RA1,AKIRIN1,CCND1,DTX3L,FUT8,RRBP1,DUSP10,ADAM15,TRIM21,IRF2,CDH3,TWIST1,HLA-C,STT3B,ARMCX6,PSMA5,RBMS2,PCGF5,CASK,KCNIP3,LGALS8,SYNE2,NUB1,SAT1,SLC11A2,PITX2,TAPBP,CASP7,PLEKHH2,CCDC6,STAT6,TBX1,MAP3K11,NOD2,SEMA3A,RARG,CBX4,EHD1 |
| 3.539e-03 | -5.64 | dephosphorylation | biological process | GO:0016311 | 275 | 58 | 16441 | 2455 |
MTM1,INPPL1,SSH1,DLGAP5,PPP1R12A,PPM1J,INPP5D,TMEM55B,UBASH3B,CTDSPL,PHOSPHO1,PLPPR4,PHLPP1,SBF1,LPIN3,DUSP5,PPP2R3A,EPM2A,INPP5E,ALPP,PTEN,OCRL,IMPAD1,PALD1,PAPL,PPP4R1,DLG1,DUSP10,PPP1CA,MINPP1,PTPRE,CTDSP2,CAMK2G,DUSP1,SSH3,PTPN18,PFKFB2,PTPRU,PTPN9,DUSP23,PTPRH,PXYLP1,DUSP4,CDC25C,SGPP1,PTPRF,NUDT16,NT5C2,PTPRJ,ATP1A1,PLPP3,PHLPP2,INPP4B,PPM1H,PPP1CB,PPP2R5D,CPPED1,CTDSP1 |
| 3.560e-03 | -5.64 | - | gene3d domains | 2.30.40.10 | 8 | 5 | 9988 | 1574 |
DPYSL5,DPYSL4,AMDHD1,DPYSL2,DPYSL3 |
| 3.568e-03 | -5.64 | Assembly of the primary cilium | REACTOME pathways | R-HSA-5617833 | 180 | 41 | 8202 | 1235 |
TTC8,LZTFL1,DYNLRB1,KIF3C,TCTN2,CEP70,TUBB4B,HDAC6,IFT27,PRKACA,CKAP5,TTC21B,INPP5E,CEP97,CNTRL,CENPJ,CEP78,SMO,PLK4,EXOC8,NEK2,TUBG1,RP2,TUBA4A,PLK1,CEP89,B9D2,CYS1,PRKAR2B,RAB3IP,NPHP3,BBS2,CDK1,ARF4,CEP162,TRAF3IP1,WDR19,SSNA1,PKD2,CEP41,NDE1 |
| 3.571e-03 | -5.63 | CORRE_MULTIPLE_MYELOMA_DN | MSigDB lists | CORRE_MULTIPLE_MYELOMA_DN | 59 | 17 | 17758 | 2588 |
EZR,TGFBR1,SLC1A3,BLVRA,FBXO6,BARD1,FOS,FBLN1,TNFRSF19,HOXA9,CDCA5,NEK2,ALDH7A1,CADPS2,HS3ST3B1,MAMDC2,SULF2 |
| 3.575e-03 | -5.63 | NPC1 (Niemann-Pick disease, type C1) | protein interactions | 4864 | 11 | 6 | 16036 | 2547 |
MRPS28,UNC93B1,FBXO6,LGR4,LGALS8,TMEM173 |
| 3.575e-03 | -5.63 | ITGAL (integrin alpha L) | protein interactions | 3683 | 11 | 6 | 16036 | 2547 |
F11R,CD82,RANBP9,ICAM5,SHARPIN,ICAM1 |
| 3.575e-03 | -5.63 | TCTN2 (tectonic family member 2) | protein interactions | 79867 | 11 | 6 | 16036 | 2547 |
NAAA,HLA-C,ATP1B3,FBXO6,HLA-E,LYPD6 |
| 3.575e-03 | -5.63 | GLS2 (glutaminase 2 (liver, mitochondrial)) | protein interactions | 27165 | 11 | 6 | 16036 | 2547 |
SNTA1,TAX1BP3,CASK,DLG3,RGS3,DLG1 |
| 3.596e-03 | -5.63 | ATN1 (atrophin 1) | protein interactions | 1822 | 101 | 27 | 16036 | 2547 |
GRN,LTBP1,CASP3,MBP,FBLN5,PLSCR1,AGRN,HSPG2,ITCH,CRIP2,TEP1,AES,JAG2,FBLN1,GIGYF1,WWP2,CASP7,PFKL,CENPJ,ALG13,MEGF8,TLE1,WWP1,DVL2,MDFI,PCSK5,DMPK |
| 3.599e-03 | -5.63 | CH | prosite domains | PS50021 | 71 | 20 | 11866 | 1802 |
LMO7,GAS2L1,SPEF2,ASPM,ARHGEF7,IQGAP1,SYNE2,UTRN,PLS1,MICALL2,SPTB,LCP1,PLS3,SMTNL2,CLMN,SPTBN5,LIMCH1,DIXDC1,TAGLN2,IQGAP3 |
| 3.608e-03 | -5.62 | STK33_SKM_DN | MSigDB lists | STK33_SKM_DN | 253 | 53 | 17758 | 2588 |
FBLIM1,CAST,GALNT12,SH3D19,PYROXD2,DDIT4L,MCTP2,ASL,PDGFRL,CA8,FLT3,FAM46C,RSAD1,BEX2,BMP2K,GBX2,SYDE2,FOXP2,CXCL16,SPIN4,CALD1,AIM1,TMEM143,ZDHHC23,SORL1,TSPAN13,ACOX2,FAM84B,RAB27B,TUBA4A,PCCB,CRIP2,OGDHL,CDA,CXorf57,TMEM144,PRKAR2B,PLS1,RAB38,CYFIP2,SNTB1,TANC1,SPNS3,CYP4F3,ARHGEF26,PRDM11,PLCH1,BANK1,PPM1H,SH3BGRL2,TANC2,CHPT1,TMEM173 |
| 3.623e-03 | -5.62 | interferon-gamma-mediated signaling pathway | biological process | GO:0060333 | 77 | 21 | 16441 | 2455 |
TRIM8,TRIM5,HLA-E,HLA-F,TRIM68,ICAM1,HLA-A,SOCS3,HLA-B,JAK1,SP100,STAT1,TRIM21,IRF2,IRF7,HLA-C,OAS3,NCAM1,TRIM62,CAMK2G,IRF1 |
| 3.636e-03 | -5.62 | GGCAGCT,MIR-22 | MSigDB lists | GGCAGCT,MIR-22 | 219 | 47 | 17758 | 2588 |
IER5L,BIN1,HSPG2,WDTC1,CALM3,IL13RA1,TGFBR1,SLC1A3,TRIB2,TTYH3,MXD1,ZFYVE9,CALM2,KHNYN,PTEN,ELF5,PIK3CD,ERBB3,CLIP2,SEPHS1,MAP3K3,SIRT1,PHF20L1,MBP,PLEKHA6,NR3C1,PTPN9,BCL9,CALM1,FURIN,PPARA,LRRC1,SLC17A5,CBL,KDM3A,PDIK1L,TRUB1,ULK2,DPYSL3,TMEM50B,BTG1,FGFR2,AGBL5,BMP1,ARRB1,STK39,CTDSP1 |
| 3.639e-03 | -5.62 | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION | MSigDB lists | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION | 236 | 50 | 17758 | 2588 |
MRC2,KLHL13,SEC61G,PSME2,HLA-F,TAP1,FBXO2,ASB9,PSMD7,PDIA3,CUL1,UBE2Z,PSMD10,UBE2Q1,RNF182,PSME1,FBXO6,PJA2,SPSB1,HLA-A,CALR,DTX3L,PSMD1,UBE2Q2,RNF220,PSMC2,UBE2J1,TRIM21,WWP1,HLA-C,PSMA5,SEC23A,SEC61B,PSMB4,TCEB2,CDC20,UBE2A,ASB13,PSMA4,SOCS3,TRIM9,HLA-B,PSMD3,UBE2D2,ERAP1,FBXO44,ITGAV,FBXO27,UBE2C,PSMC1 |
| 3.641e-03 | -5.62 | CBL (Cbl proto-oncogene, E3 ubiquitin protein ligase) | protein interactions | 867 | 233 | 53 | 16036 | 2547 |
SCN5A,INPPL1,SORBS1,TUBB4B,INPP5D,IQGAP1,UBASH3B,ARHGEF7,RET,FLOT1,ERBB2,SORBS3,FLT3,SH3KBP1,IGF1R,CTNNB1,PTEN,SNX18,PIK3CA,TRIM21,OSTF1,NOTCH3,SPRY2,SYK,FRS3,TRIM8,ITCH,CALM1,PIK3R1,PRKCQ,YES1,CD40,CBL,BCAR1,TCN2,EGFR,TNS4,PLCG1,FYN,INSR,FGFR2,CSF1,CORO1C,AXL,LRIG1,UBE2D2,MAP3K11,SPRY4,ITGAV,F2RL1,CAPN1,CD33,IRF1 |
| 3.651e-03 | -5.61 | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN | 191 | 42 | 17758 | 2588 |
LAMP1,LASP1,ACTR8,DCAF7,MCTP2,PDCL,TXNDC9,BARD1,TIPRL,VPS26A,ZFYVE16,PHTF1,PLCG2,FAM13B,FAIM,NCAM1,PTPRE,APOBEC3G,ENPP4,CPD,ARAP2,MLEC,ASPM,STAU2,ITCH,VPS4B,GALNT7,YES1,POLD3,PCTP,IDH1,ATP10D,DDX23,ZMPSTE24,GALNT3,UTP14C,DCUN1D1,STK39,TRAF5,SLC27A3,C17orf75,PRKAR1A |
| 3.651e-03 | -5.61 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | 191 | 42 | 17758 | 2588 |
LZTFL1,ANKRD13D,ARMCX3,AGRN,PPP1R12A,IBTK,FAM199X,ARHGEF11,ATP8A1,NDRG1,FAM134A,GMCL1,EGR3,SNN,SEPP1,KCTD9,OTUD1,RB1,CTSC,MAGEE1,FAM13B,DAPK1,FNIP1,BRI3,FAR1,MGAT5,EPHX1,ALDH2,PLAUR,BCL9,PLEKHO1,PRICKLE1,KIF13A,SESN1,C3orf58,XKRX,PTPRF,TSC1,AP1AR,TMEM164,TWSG1,ZBTB33 |
| 3.651e-03 | -5.61 | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP | 191 | 42 | 17758 | 2588 |
CASP3,MTM1,RECQL,SORBS1,LGALS3,MRPS15,CDCA8,LACTB2,CA2,IGF1R,CD22,CD9,KIF22,RGS5,AK3,HSPA2,SYK,SMC4,ALDH2,CXXC5,IFITM3,AMFR,LITAF,AURKB,CD40,DOCK5,ALCAM,TP53INP2,GABARAPL1,AHRR,PIAS3,GALNT3,CARHSP1,ENPP1,SWAP70,TWSG1,KPNA2,CTSA,ITGAV,CD81,MAD2L1BP,JARID2 |
| 3.651e-03 | -5.61 | malignant_fibrous_histiocytoma-pleomorphic_sarcoma | COSMIC cancer mutations | malignant_fibrous_histiocytoma-pleomorphic_sarcoma | 36 | 12 | 17775 | 2585 |
KIF5B,RB1,SS18,CTNNB1,CDH1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 3.651e-03 | -5.61 | carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | carcinosarcoma-malignant_mesodermal_mixed_tumour | 36 | 12 | 17775 | 2585 |
RB1,NF2,CTNNB1,AKT1,FGFR2,PTEN,MSH2,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 3.661e-03 | -5.61 | polysaccharide biosynthetic process | biological process | GO:0000271 | 44 | 14 | 16441 | 2455 |
PGM1,B3GNT2,UGP2,AKT1,CSGALNACT1,GYS1,PGM2L1,NANS,B4GAT1,EXT2,GLT8D2,PHKG2,EPM2A,PER2 |
| 3.661e-03 | -5.61 | metaphase plate congression | biological process | GO:0051310 | 44 | 14 | 16441 | 2455 |
RB1,PSRC1,KIF14,CDCA5,FAM83D,VPS4B,CDCA8,KIF22,CHMP4B,CENPE,KIF2C,GEM,CCNB1,SPDL1 |
| 3.676e-03 | -5.61 | PID_ILK_PATHWAY | MSigDB lists | PID_ILK_PATHWAY | 45 | 14 | 17758 | 2588 |
MYL9,CCND1,ZYX,PPP1R12A,CTNNB1,AKT1,ELMO2,IQGAP1,ARHGEF7,AURKA,TNS1,PPP1R14C,ILK,CKAP5 |
| 3.678e-03 | -5.61 | positive regulation of nucleic acid-templated transcription | biological process | GO:1903508 | 1423 | 248 | 16441 | 2455 |
CCNC,ACVR1,TRIM24,AGRN,LGR4,EPAS1,TRIM5,HEXB,RET,GATA3,MORF4L2,CAMK1D,PDGFB,TFAP2E,TP73,EPCAM,HELZ2,HSF2,CTNNB1,GRHL1,NPNT,PSMC2,IL31RA,MITF,FOSB,ELF5,DNM2,IRF2,ASH2L,ARNT2,MYBL1,ZNF462,THRB,NEK4,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,ASXL1,NFE2L1,TFAP2C,EAF2,LDB2,SAV1,ARF4,SEC14L2,AHRR,MDK,KLF12,TBX1,NOD2,HDAC1,RNASEL,TRAF5,F2RL1,E2F8,PSMC1,MAFF,HOXC13,NR2C2,DDX58,KLF2,RUNX2,CDKN1C,PPP1R12A,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,BMP2,TFAP4,RB1,CYR61,GATA2,EBF4,PRKCI,MDFIC,MYDGF,WNT3A,MAPK7,NUP85,ELK3,RGMB,SALL4,STAT4,FHL2,MYBL2,ELK1,ILK,TP53INP2,KDM3A,NFIB,EGFR,ONECUT1,NCOA3,SERTAD2,INSR,ETS2,PLPP3,SETD3,NFKBIA,PIAS2,NLRC5,NR4A2,RARG,RPS6KA3,TMEM173,KLF7,IRF1,RAD21,PAX6,ARMCX3,GRHL2,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,CCNL1,LPIN3,SS18,CCNA2,CDH1,SP100,LMO4,SMO,DAB2IP,ZBTB49,TWIST1,NOTCH3,NFKB2,F2R,ETV4,MED30,DVL2,CTH,SIRT1,PSRC1,RIPK2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,EBF2,FZD7,NFIX,JADE1,HSF4,RBL1,STAT6,WWTR1,STAT1,KLF5,IRF7,NRG1,AKNA,ARNT,ATMIN,GLIS3,ANXA3,PINK1,NKX3-1,CKAP2,TAB3,ARHGEF11,TRAF2,PBX3,TGFBR1,HMGN3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,GBX2,IRF2BPL,TOP2A,E2F7,IRAK1,PTEN,BMP7,MCF2L,TOX2,GTF2F2,TFAP2A,TRIM21,BRD7,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,NFE2L3,HES1,DCAF6,CASK,PLSCR1,WNT10B,HMGN5,NR3C1,BCL9,NR4A1,TEF,PIK3R1,GRIN1,PPARA,RGCC,MAML2,RUNX3,YES1,FOS,ABLIM2,BCL10,TXK,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,NR1D2,ACVRL1,E2F1,NR4A3,ARRB1,PKD2,GPER1,HMGA1,SOX8,ZMIZ1,OSR1,FZD5,CD81,SHOX2,USF2,AHR,FOXA1,USP16,RGMA |
| 3.678e-03 | -5.61 | positive regulation of transcription, DNA-templated | biological process | GO:0045893 | 1423 | 248 | 16441 | 2455 |
CCNC,ACVR1,TRIM24,AGRN,LGR4,EPAS1,TRIM5,HEXB,RET,GATA3,MORF4L2,CAMK1D,PDGFB,TFAP2E,TP73,EPCAM,HELZ2,HSF2,CTNNB1,GRHL1,NPNT,PSMC2,IL31RA,MITF,FOSB,ELF5,DNM2,IRF2,ASH2L,ARNT2,MYBL1,ZNF462,THRB,NEK4,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,ASXL1,NFE2L1,TFAP2C,EAF2,LDB2,SAV1,ARF4,SEC14L2,AHRR,MDK,KLF12,TBX1,NOD2,HDAC1,RNASEL,TRAF5,F2RL1,E2F8,PSMC1,MAFF,HOXC13,NR2C2,DDX58,KLF2,RUNX2,CDKN1C,PPP1R12A,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,BMP2,TFAP4,RB1,CYR61,GATA2,EBF4,PRKCI,MDFIC,MYDGF,WNT3A,MAPK7,NUP85,ELK3,RGMB,SALL4,STAT4,FHL2,MYBL2,ELK1,ILK,TP53INP2,KDM3A,NFIB,EGFR,ONECUT1,NCOA3,SERTAD2,INSR,ETS2,PLPP3,SETD3,NFKBIA,PIAS2,NLRC5,NR4A2,RARG,RPS6KA3,TMEM173,KLF7,IRF1,RAD21,PAX6,ARMCX3,GRHL2,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,CCNL1,LPIN3,SS18,CCNA2,CDH1,SP100,LMO4,SMO,DAB2IP,ZBTB49,TWIST1,NOTCH3,NFKB2,F2R,ETV4,MED30,DVL2,CTH,SIRT1,PSRC1,RIPK2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,EBF2,FZD7,NFIX,JADE1,HSF4,RBL1,STAT6,WWTR1,STAT1,KLF5,IRF7,NRG1,AKNA,ARNT,ATMIN,GLIS3,ANXA3,PINK1,NKX3-1,CKAP2,TAB3,ARHGEF11,TRAF2,PBX3,TGFBR1,HMGN3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,GBX2,IRF2BPL,TOP2A,E2F7,IRAK1,PTEN,BMP7,MCF2L,TOX2,GTF2F2,TFAP2A,TRIM21,BRD7,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,NFE2L3,HES1,DCAF6,CASK,PLSCR1,WNT10B,HMGN5,NR3C1,BCL9,NR4A1,TEF,PIK3R1,GRIN1,PPARA,RGCC,MAML2,RUNX3,YES1,FOS,ABLIM2,BCL10,TXK,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,ACVRL1,NR1D2,E2F1,NR4A3,ARRB1,PKD2,GPER1,HMGA1,SOX8,ZMIZ1,OSR1,FZD5,CD81,SHOX2,USF2,AHR,FOXA1,USP16,RGMA |
| 3.679e-03 | -5.61 | ST_FAS_SIGNALING_PATHWAY | MSigDB lists | ST_FAS_SIGNALING_PATHWAY | 64 | 18 | 17758 | 2588 |
CASP3,NFKBIE,RALBP1,TRAF2,XIAP,TP53,EZR,NFAT5,EGFR,NCS1,MAPK8IP1,FAS,NFKBIA,BAX,ALG2,NFKB2,MAP3K5,HSPB1 |
| 3.680e-03 | -5.60 | negative regulation of locomotion | biological process | GO:0040013 | 253 | 54 | 16441 | 2455 |
SEMA6B,TCAF1,ARAP3,NF2,ADGRG1,TRIM5,PKP2,GATA3,VASH1,FBLN1,GRM5,CORO1B,NOV,SVBP,PDCD10,TIMP1,ADORA1,SP100,PTEN,ADAM15,DAB2IP,TACSTD2,SEMA3G,CITED2,WNT3A,CYP1B1,SEMA3B,TRIM8,IFITM3,ACVR1C,PTPRU,PTGER4,RGCC,ARHGDIB,EPHA1,ILK,DAG1,RHOB,ABR,DPYSL3,AP1AR,PTPRJ,SEMA4D,ACVRL1,CORO1C,SPINT2,RAP2C,EGFL7,NRG1,ITGAV,ARHGAP4,SEMA3A,MIIP,DRD1 |
| 3.685e-03 | -5.60 | human chr2q36.1 | chromosome location | human chr2q36.1 | 11 | 5 | 26250 | 2805 |
WDFY1,MRPL44,SERPINE2,ARPC2,EPHA4 |
| 3.686e-03 | -5.60 | toll-like receptor 3 signaling pathway | biological process | GO:0034138 | 87 | 23 | 16441 | 2455 |
UNC93B1,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,NFKBIA,UBE2D2,NOD2,MAPK11,IRF7,MAP3K7,SCARA3,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 3.686e-03 | -5.60 | regulation of cell-matrix adhesion | biological process | GO:0001952 | 87 | 23 | 16441 | 2455 |
EPB41L5,CASK,NF2,FMN1,DMTN,PIK3R1,SDC4,UTRN,EPHA1,ILK,EMP2,RASA1,ONECUT1,TSC1,PTPRJ,PTEN,ACVRL1,CSF1,CORO1C,BCL6,ADAM15,EFNA5,COL16A1 |
| 3.687e-03 | -5.60 | LIU_PROSTATE_CANCER_UP | MSigDB lists | LIU_PROSTATE_CANCER_UP | 89 | 23 | 17758 | 2588 |
BCAM,FARP1,REPS2,ST14,SOX9,PDIA5,TP53,EIF2AK1,GDF15,GALNT7,ELK1,TRIM68,ARHGEF26,CALR,EPCAM,UAP1,LRIG1,ALDH1A3,CANT1,ECI2,TSPAN13,RAP1GAP,TBC1D4 |
| 3.692e-03 | -5.60 | YYCATTCAWW_UNKNOWN | MSigDB lists | YYCATTCAWW_UNKNOWN | 180 | 40 | 17758 | 2588 |
RECQL,LGALS3,NF2,HOXB7,ETV5,TRIB2,NCS1,ZDHHC21,CCND1,AIM1L,ZCCHC17,IGF1R,CYR61,RGS3,BMP7,RANBP1,FOSB,TSPAN13,ETV4,PLCB2,SCN3A,EBAG9,CASK,GCLC,PRKAR2B,DUSP4,GOLT1A,SP4,TSC1,FYN,ETS2,KLF12,HTT,DNM1L,SCG2,MFSD2A,NR4A3,SPRY4,TOB1,MAFF |
| 3.692e-03 | -5.60 | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN | 180 | 40 | 17758 | 2588 |
UGP2,IL15RA,SDC4,APOO,SOD2,CD274,SLC1A3,OSR2,CCNB1,ICAM1,RND1,IER3,E2F7,BTG3,ITGB8,SNX18,PIK3AP1,FJX1,DRAM1,SNX10,RIPK2,RAPGEF2,PIM3,CD40,SAV1,RNF19B,CDK1,NIN,SOCS3,CD83,PTGS2,PI4K2B,PTPRJ,NFKBIA,SLC2A6,RAP2C,NFKBIZ,HS3ST3B1,IFIH1,EHD1 |
| 3.692e-03 | -5.60 | GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP | 180 | 40 | 17758 | 2588 |
TMEM184B,FAM160B1,DNAJC3,ADO,GNE,EFHD2,SLC36A4,PHLPP1,SNN,HMGXB4,NAPG,IRAK1,CTNNB1,SLC16A5,CKAP4,VPS11,B3GNT7,TRIM8,TACC1,KCTD20,UBAC1,RUNX3,ZDHHC3,C18orf8,CD83,CRTC2,MAPKAPK2,SERTAD2,MADD,RIN3,PLA2G15,CCDC69,ZDHHC7,PITPNA,NR4A2,KLF11,ZBTB34,SAT2,LRRC57,CAPN1 |
| 3.693e-03 | -5.60 | RIZKI_TUMOR_INVASIVENESS_3D_DN | MSigDB lists | RIZKI_TUMOR_INVASIVENESS_3D_DN | 259 | 54 | 17758 | 2588 |
INPPL1,XIAP,IL18,PSME1,ITPR2,BCAP31,BMP2,PDCD10,OXCT1,LRRN2,BMP7,OCRL,BDH1,LHX6,PRKG1,SORL1,SGK1,OSTF1,HMGCL,HSPA13,MANF,PIK3CD,HLA-C,OAS3,CTSD,LOXL1,PHKG2,LAMP3,PLK1,BAG4,CENPA,CELSR2,PAPD7,RNF11,GGH,DUSP4,SNTB1,MEST,ICMT,POLD3,ZFAND5,PSMA4,CD83,IL1R1,SLC25A4,ACVRL1,FGF18,ABCB1,SSNA1,MAP3K5,RAP1GAP,CD81,SLC31A2,MYL12B |
| 3.694e-03 | -5.60 | membrane organization | biological process | GO:0061024 | 959 | 173 | 16441 | 2455 |
SUN1,DOC2A,AGRN,GRIK2,ATP8A1,F11R,MPP5,SYTL4,CCNB1,SNX9,MAP1LC3B,SPTB,PICK1,CALM2,NAPG,RAB15,AP1M2,NUP210,DLG1,DNM2,SUN3,RAB20,TFG,ANO4,PACSIN1,TRAM1,CPE,XKR8,PLK1,VPS11,SOD1,KCNIP3,SYNE3,BNIP3L,EZR,ARFRP1,KIF13A,ICMT,MCFD2,CDK1,OPTN,DNM1L,AREG,TC2N,PRKAA2,TBC1D1,SEC61G,ETV5,CALM3,CNTNAP2,LMNA,ATG4A,RPL39,KCNN4,FCHO1,EXOC8,PRKCI,SRP54,SYTL3,NUP85,PPP6R1,TSPAN33,CCDC88A,TMED2,GCC2,CALM1,ANO6,ATP8B3,ZDHHC3,EGFR,STX3,PRKAG2,FA2H,HTT,PVRL2,TMEM30A,ZDHHC20,RAB31,ZDHHC7,DYSF,ATP1B3,CCNB2,NUP58,DMPK,SLC2A4,NDRG1,APOO,TP53,P2RX7,PKP2,FTH1,BCL2L1,EMP2,SYTL2,CDH1,ZDHHC12,REEP1,ZDHHC23,RPN2,DLG3,LMAN1,FLOT2,CHP1,ATG4D,PPIF,GCA,CLCN3,SEC23A,SEC61B,BAG4,MBP,AKT1,TMEM43,SYNE2,VPS4B,SYP,ATP1B1,RAB38,ATP10D,GABARAPL1,ZMPSTE24,PEX5,DDOST,CHMP4B,SYT13,RPL22,REEP4,ABCA1,CNEP1R1,COPG1,TAOK2,PLSCR4,PACSIN2,TRAPPC10,TSPAN15,SH3D19,ATP9A,LRP4,FLOT1,CTSZ,ANO9,TSPAN17,ZDHHC21,ANK1,ADORA1,CTSC,PTEN,A4GALT,BAX,CD9,ATP8B1,PLEKHF1,MYO5A,SUN2,RAB3B,PLSCR1,CRB3,RAPGEF2,VAMP3,COL7A1,RAB3IP,BBS2,LEMD2,RPL12,FAT4,SERPINA1,SYT7,ARRB1,SSNA1,SPCS3,GPER1,NUP37,TBC1D4 |
| 3.695e-03 | -5.60 | TSPAN4 (tetraspanin 4) | protein interactions | 7106 | 8 | 5 | 16036 | 2547 |
CD46,ITGA3,CD81,ITGA6,CD9 |
| 3.695e-03 | -5.60 | QSOX1 (quiescin Q6 sulfhydryl oxidase 1) | protein interactions | 5768 | 8 | 5 | 16036 | 2547 |
RP2,RBM24,LYPD3,GLT8D2,UBE2D2 |
| 3.695e-03 | -5.60 | CLCN7 (chloride channel, voltage-sensitive 7) | protein interactions | 1186 | 8 | 5 | 16036 | 2547 |
FAM177A1,LGALS8,LYPD3,OSTM1,MCOLN3 |
| 3.709e-03 | -5.60 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | 169 | 38 | 17758 | 2588 |
KLHL13,TMEM41B,CCDC110,ITGA6,SNN,NUCB2,NUDT12,KBTBD11,PIGL,DDR1,DENND2D,LTBP3,CHST2,ZNF275,IGF1R,IL6ST,DACT1,PIK3CD,ALS2CL,TPCN1,CD55,MPP1,BNIP3L,TCF7,EPHA1,KLHL2,SERTAD2,H1F0,RIN3,CDCA7L,NFKBIZ,EFNA1,CEP41,APBA2,NDFIP1,SNPH,KLF7,PCSK5 |
| 3.709e-03 | -5.60 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP | 169 | 38 | 17758 | 2588 |
UBASH3B,NDRG1,TSC22D3,EPHA4,SYTL2,DNAJB9,CAPN2,OTUD1,ABCA2,SGK1,PDE4D,CITED2,MYLIP,C9orf72,SLC16A5,SMAGP,DUSP1,SUSD3,KIFC2,ITCH,COQ10B,SAT1,BNIP3L,DIAPH2,FOS,SOCS3,IRS2,PTPRJ,PELI2,CSGALNACT1,CCDC69,YOD1,NR4A2,RELL1,TOB1,MAFF,KLF7,FAM134B |
| 3.710e-03 | -5.60 | plasma membrane part | cellular component | GO:0044459 | 2566 | 422 | 17570 | 2579 |
LAMP1,ACVR1,LGR4,VANGL1,GRIK2,SLC25A13,RET,CACNA2D2,PLXNA1,SYTL4,PJA2,SNX9,SLC20A1,NCS1,PICK1,GRM5,ZYX,TGFBR3,MUC4,STIM1,CABP1,SLC46A1,ATP13A3,STEAP2,FUT1,KCNS3,DNM2,CLDN4,TACSTD2,PACSIN1,TIAM1,CPE,IL10RB,SGCE,ACVR1C,SNTB2,MGAM,SLC17A5,SLC25A5,ARF4,LCP1,ENPP1,SLC25A4,GRID2IP,ATP7B,NOD2,SPRY4,ARF6,TRAF5,F2RL1,SLC31A2,LZTS1,DDX58,SEMA6B,SCN5A,HLA-E,ITGA6,PRKAA1,ZNRF3,SLC1A3,NOTCH2,MERTK,TSPAN7,CALR,ITGA3,ZNRF2,SNX18,LYPD3,SLC16A6,CD22,FLRT3,OPN3,SORL1,CD70,CNGA1,CACNA1D,NCAM1,ULBP2,SYTL3,RIMS2,TSPAN33,GPR161,EPB41L5,FADS2,KCNJ12,MFI2,MMD,PTPRH,CALCRL,EPHA1,ANTXR1,GNA11,STX3,RASA1,FAS,PTPRF,IL1R1,MMP15,GABRD,SLCO4A1,TJP3,SLC4A4,SEMA4D,MPP2,SLC4A3,DYSF,OSMR,STK39,OSCP1,EFNA1,MAL2,TRPC3,RUSC1,EHD1,SPRED1,SLC2A4,TCTN2,ST14,TRIP10,CD82,IQGAP1,ATP2C2,KCTD12,IL13RA1,CD274,APC2,PRKACA,DDR1,FLT3,KTN1,EPS8L2,CD46,SCNN1A,CDH1,CNNM4,DAB2IP,EPHB4,PDE4D,TSPAN1,DLG3,RAB27B,FLOT2,SCN3A,FZD4,DMTN,SYNE2,CYS1,CLSTN1,UTRN,SLC11A2,PRKCQ,SYP,ATP1B1,ITPR3,TANC1,CBL,ALCAM,GABARAPL1,EPHA10,FYN,JAK1,STK26,SHROOM3,CORO1C,AXL,SIPA1L1,TSPAN18,TRABD2A,SLC27A1,NRG1,HS3ST3B1,PRIMA1,RGS14,PRKAR1A,TTC8,FARP1,MPZL1,TRAF2,BACE1,SDC4,EPS8,FLOT1,PLD2,PLPPR4,SLC35G2,KCNC4,EFNB1,TSPAN17,SRPX2,HLA-A,ICAM1,NEO1,SNTA1,ANK1,IRAK1,ITGB8,PTEN,ANKS1B,GPC3,KCNK5,CD9,ATP8B1,TMBIM6,IGFBP2,ERBB3,SGCB,SPRY2,SLC16A5,S100A6,HCN3,AMOTL2,PVRL4,CASK,PLSCR1,MPP1,RAPGEF2,GRIN1,VAMP3,YES1,AIF1L,SNTB1,TXK,CNTNAP1,RGS9,PROM1,LDLRAP1,ACVRL1,FGFR2,RYK,GRIN2D,GPER1,ITGAV,CD81,OCLN,CYBRD1,ESYT2,CASP3,BCAM,TNK1,EPHA4,HDAC6,SDC1,PDGFB,CACNB4,SLC9A3R2,TMC1,SPTB,HTR1D,ABCD4,EPCAM,TM9SF2,CTNNB1,P4HB,CDKL5,NPNT,TSPAN6,IL6ST,DLG1,ABCA2,TRPC1,TNFRSF18,RP2,CTTN,MYRIP,IL1RAP,SMAGP,CD55,KCNIP3,EZR,CR2,ROR1,EDNRA,HS6ST1,KCNMB4,KCNK1,PRKCDBP,ADIPOR1,PIEZO1,CD99,SERPINE2,LGALS3,BVES,RASA2,FXYD3,HLA-F,SLC22A31,RACGAP1,CNTNAP2,TEC,NCKAP1,DHRS3,ANO1,BMP2,VASP,CA2,IGF1R,NOXA1,ICAM5,KCNN4,TBCD,PRKCI,FXYD5,HLA-C,NPTN,C10orf54,TMEM8A,SLC12A2,ABCC1,PODXL2,PCDH1,RGMB,SPA17,SPATA13,SCRIB,STEAP1,EGFR,RASGRP2,EPN3,GNAS,SLC6A6,INSR,PVRL2,COL13A1,MFSD2A,ITGA7,TMEM30A,PHLPP2,PLPP3,PLD1,ATP1B3,JAK3,SHROOM2,DRD1,PROM2,SORBS1,NF2,IL15,SLC2A8,ERBB2,P2RX7,IL27RA,RASGRP3,SLC7A2,PRR7,EMP2,BCAP31,SYTL2,SMO,STEAP3,ECE1,SCN2A,F2R,HSPA2,GM2A,CLCN3,PTPRU,ERBB2IP,CD40,DAG1,ATP13A2,DUOX1,PTGS2,PTPRJ,RTN4RL1,ATP1A1,ABHD12,PTK7,MMP17,SPTBN5,CHMP4B,EFNA5,PLXND1,SYT13,LIFR,ABCA1,BIN1,PACSIN2,TSPAN15,CD63,ADGRG1,CTSB,LRP4,GNAL,SELL,GABRG2,TGFBR1,JAG2,ITGA2B,XPR1,FZD6,M6PR,IL17RB,ADORA1,CDK16,MAGEE1,IL17RA,TSPAN13,IQGAP3,SLC35A1,SYK,ATP2B1,DLGAP1,P2RX4,SYPL1,ADAM17,RHOA,CRB3,PLAUR,BBS2,CD83,BCL10,HLA-B,CD8A,CTSV,NETO2,ARRB1,PKD2,GEM,L1CAM,CD33,ABCG1,ARHGEF4 |
| 3.717e-03 | -5.59 | SUBTIL_PROGESTIN_TARGETS | MSigDB lists | SUBTIL_PROGESTIN_TARGETS | 36 | 12 | 17758 | 2588 |
MAP3K3,CCND1,CDKN1C,CYR61,IL6ST,RPS6KA1,ECI2,BCAR1,GM2A,H1FX,HDAC9,DUSP1 |
| 3.717e-03 | -5.59 | CUI_TCF21_TARGETS_UP | MSigDB lists | CUI_TCF21_TARGETS_UP | 36 | 12 | 17758 | 2588 |
MDK,HMMR,COL6A2,HJURP,EPHA4,HDAC11,COL6A1,CDKN1B,IGFBP2,NCAM1,LHFPL2,IGDCC4 |
| 3.717e-03 | -5.59 | ZHAN_MULTIPLE_MYELOMA_MF_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MF_DN | 36 | 12 | 17758 | 2588 |
ALDH2,TRANK1,RAPGEF2,CCDC110,FAM3C,RAD17,CAMK1D,TMEM170B,MOXD1,GLCCI1,ZNF275,DOCK9 |
| 3.726e-03 | -5.59 | JIANG_VHL_TARGETS | MSigDB lists | JIANG_VHL_TARGETS | 131 | 31 | 17758 | 2588 |
LAMP1,HN1L,ENO2,ZNF395,TRIP10,RPS6KA1,NFE2L1,C6orf106,BCL7B,HDAC6,GTF2A2,MRPS36,PNKD,RANBP9,RHOB,IRF2BPL,SCARB2,SS18,PCNA,ARTN,KBTBD2,APPL2,PPP1CB,UACA,PPP2R5D,GM2A,CAPN1,CKAP4,KDELR1,WBP5,IRF1 |
| 3.727e-03 | -5.59 | ACTGCCT,MIR-34B | MSigDB lists | ACTGCCT,MIR-34B | 208 | 45 | 17758 | 2588 |
TRIM2,FRMD4A,RBM24,DCAF7,CACNA2D2,MAPK4,ETS1,NFAT5,TMCC3,ARHGEF10L,SNTA1,RALGPS2,PPP1R10,ANKS1B,STIM1,LMAN2L,OCRL,MITF,ANKRD12,ARNT2,MYRIP,FLOT2,ABCC1,CERS2,THRB,CAPN6,TESK1,FOXJ2,VAMP3,FHL2,VEZT,ALCAM,COL12A1,GLCE,NFIX,ZMPSTE24,CNTNAP1,MAN2A2,PPP2R5A,KLF12,PTK7,NRG1,NR4A2,STK39,ATP1B3 |
| 3.733e-03 | -5.59 | regulation of cellular response to stress | biological process | GO:0080135 | 620 | 117 | 16441 | 2455 |
SPRED1,TXN,GRIK2,FOXM1,DNAJC3,EPHA4,SOD2,TP53,BCL2L1,VASH1,HDAC6,MAP1LC3B,ERP29,BCAP31,EPM2A,IER3,TP73,PCNA,NUP210,CTGF,P4HB,RALB,DACT1,BCL6,DLG1,DUSP10,DAB2IP,TWIST1,CTTN,CDKN2D,RNF169,RASGRP1,DVL2,MAP3K3,NEK4,SIRT1,SOD1,ERLEC1,BAG4,RIPK2,AKT1,FIGNL1,FZD4,ITCH,PBK,CASP9,BNIP3L,EZR,MAP3K6,FZD7,KDM4D,DNM1L,ANKRD6,STK26,WFS1,KIAA1804,NOD2,MAP3K11,CHMP4B,POMT1,HSPB1,F2RL1,GAB1,LZTS1,PRKAA2,PINK1,TAOK2,NKX3-1,SCOC,NUAK1,TRAF2,PSMD10,PKN1,PHLPP1,GSTP1,FGF19,MECOM,BMP2,SPP1,PDCD10,IGF1R,PTEN,BMP7,BAX,UBE2J1,MAP3K9,TMBIM6,MDFIC,USP1,PIKFYVE,MAPK7,MAP3K7,SYK,NUP85,CAMK2G,MDFI,QSOX1,FBLN5,PIK3R1,PIP4K2C,WHSC1,EIF2AK1,MAPK8IP1,EGFR,FECH,MAPKAPK2,PTPRF,NUDT16,NR4A3,YOD1,HMGA1,FZD5,NUP37,MAP3K5,HIPK3,NUP58,XDH |
| 3.735e-03 | -5.59 | RGAGGAARY_V$PU1_Q6 | MSigDB lists | RGAGGAARY_V$PU1_Q6 | 477 | 91 | 17758 | 2588 |
PLA2G4A,TNK1,PAX6,GPR107,XIAP,ARFGEF1,CCDC68,RASGRP3,CAMK1D,ITPR2,DPP8,RGS12,NPNT,TAX1BP3,TWIST1,RAB20,ACSL4,OSBPL7,TBC1D10B,LAMP2,CXXC5,UXT,PPP1R14C,RAB2B,SEC14L2,ATP13A2,FYN,PTPRJ,PTK7,CORO1C,SH2D3C,PRDM5,VSIG10,CTNND1,LEMD1,STARD13,NR3C2,DLAT,PCSK5,IER5L,SEMA6B,CPEB4,POC1B,SLC41A1,HMGN3,FAM81A,PKN1,DOCK11,NFAT5,PSIP1,ITGA2B,IRF2BPL,TFAP4,CD109,RAC2,ADD3,VASP,ADORA1,PIK3AP1,CYR61,RINL,SLC16A6,ATP5H,VASN,ADAM15,CACNA1D,ERBB3,NPTN,CNOT6L,NCAM1,DLX4,PLCB2,PTPRH,PRICKLE1,POLD3,GLT8D2,DDX23,PITX2,SYT7,ACVRL1,CSF1,ARAP1,CTSA,EFNA1,ATP1B3,NDFIP1,ZNF502,AHR,ACOT7,FOXA1,ARHGEF4 |
| 3.737e-03 | -5.59 | regulation of cell size | biological process | GO:0008361 | 176 | 40 | 16441 | 2455 |
SEMA6B,ADD1,RET,WDTC1,P2RX7,PLXNA1,CRABP2,TP73,SPP1,PTEN,CDKL5,DPYSL2,MEGF8,KCNN4,DNM2,TNFRSF12A,CTTN,SEMA3G,IQGAP3,NTN1,WNT3A,SLC12A2,SEMA3B,CLCN3,AKT1,ANO6,EZR,ILK,ULK2,CDK5R1,MAP1B,TSC1,SEMA4D,LIMK1,EFNA5,NRG1,PLXND1,SEMA3A,RARG,L1CAM |
| 3.740e-03 | -5.59 | V$NFKAPPAB_01 | MSigDB lists | V$NFKAPPAB_01 | 242 | 51 | 17758 | 2588 |
BMF,SDC4,TP53,IL27RA,TRIB2,DDR1,NFAT5,SPTB,BMP2K,ICAM1,RND1,CXCL16,CTGF,SLC44A1,ANKFN1,KCNS3,CD70,NFKB2,NTN1,SLC12A2,RIMS2,XKR8,CPD,SUN2,WNT10B,TNIP1,FOXJ2,SLC11A2,ATP1B1,CD40,PNKD,PRX,CYB5A,SEC14L2,CD83,TRIM47,BFSP1,STAT6,RAP2C,NOD2,FAM117A,UACA,GRIN2D,SP6,ARPC2,SHOX2,JAK3,GEN1,COL16A1,JARID2,IRF1 |
| 3.740e-03 | -5.59 | multicellular organismal process | biological process | GO:0032501 | 6447 | 1023 | 16441 | 2455 |
DOC2A,HECA,ADD1,GRIK2,AK7,HEXB,RET,MCOLN3,NRG2,IL18,BARD1,KIF26A,LTBP3,GRM5,TP73,NPM2,CALM2,CDKN2C,WEE1,PSMD1,TGFBR3,MUC4,PAQR5,ALDH1A3,SLC46A1,RDH14,KLF3,DNM2,CLDN4,CRY2,SEMA3G,PPP1CA,PIK3CD,TIAM1,TIPARP,CPE,ERAP2,TUBA4A,SPEF2,SMARCA2,TFAP2C,PRKAR2B,LOXL2,F12,ICMT,RNF19B,MYOM1,PNKD,ARF4,GINS4,COL12A1,ABR,PGF,ENPP1,PLCG1,DNM1L,LIMK1,ATP7B,TRAF3IP1,MYLK,NOD2,HDAC1,SERPINB6,TMOD2,ITPKA,LSM14B,ARF6,HSPB1,E2F8,GAB1,HOXC13,SCN5A,TMTC3,ITGA6,SOX9,MTL5,RAB23,GPSM2,MERTK,HPCAL4,LMNA,RABGGTA,ELF3,FLII,RAC2,FRY,MEGF8,FLRT3,ZIC5,NEK2,USP1,MYDGF,CNGA1,NCAM1,DGKG,MYLIP,NDUFA12,PAQR7,REC8,UFD1L,SALL4,SHARPIN,FHL2,CALCRL,PLS1,KIF20B,NPHP3,ILK,TP53INP2,DPYSL4,GNA11,PSMA4,RHOB,PTPRF,IL1R1,NCOA3,ETS2,TIMM8A,HTT,SEMA4D,ITPR1,DGAT2,AURKA,CLMN,STK39,B4GAT1,GDF11,NDE1,DRP2,ARPC2,CFAP20,CBX5,TRPC3,RPS6KA3,TMEM173,CSRP2,XDH,ADAMTS16,EGLN1,DOCK9,DMPK,TPRN,GRHL2,PAPSS2,LFNG,INPP5D,PTTG1,WDTC1,PKP2,TESK2,PRKACA,APC2,TNFSF9,CCND1,RCN1,SCNN1A,CDH1,DACT1,RTKN2,ACSL4,LRP11,DLG3,RASGEF1A,CDKN2D,MYT1,SNX10,ETV4,SCN3A,ENPP4,CAMSAP3,SSH3,COL6A2,LGALS8,FZD4,SAT1,HTATIP2,TANC1,EBF2,NFIX,IRS2,SPIN3,PDLIM3,SHROOM3,CORO1C,WFS1,SLC9A6,AXL,SIPA1L1,WWTR1,PNPLA6,RGS14,ARNT,MAPK12,TTC8,CTHRC1,FARP1,NKX3-1,TNRC6C,MAN1A2,DCAF7,CCM2,BIK,SDC4,HABP4,FLOT1,BTN3A1,GMCL1,CTSZ,PKN1,PLPPR4,ZNF219,ETS1,GSTP1,NFAT5,SRPX2,HOXB2,ICAM1,SGPL1,NEO1,CTNNBIP1,CAPN2,ZFX,ANK1,PDCD10,ITGB8,IGSF9,KNDC1,KCNK5,GPC3,CALD1,CST3,BAX,ADAM15,TMBIM6,WWP1,IGFBP2,AK3,RAG1,SGCB,ITM2C,S100A6,CRTAP,POU6F1,ADAMTS2,LCA5,PLSCR1,TACC1,FMN1,BCL9,RAPGEF2,PIK3R1,EIF5A2,GRIN1,UBE2A,AK4,SNTB1,CRISPLD2,ABLIM2,TXK,CNTNAP1,PITX2,BTG1,LDLRAP1,PROM1,RAB11FIP2,ACVRL1,DBI,FAM3C,NR4A3,ITGAV,CENPE,FHL1,OSR1,USF2,SHOX2,FOXA1,PHC1,TLL2,MYL9,CCNI,AGRN,EPAS1,CUL4B,EPHA4,SUDS3,ARFGEF1,PHOSPHO1,NDRG2,F11R,ITPR2,PDGFB,SDC1,SPTB,SLC9A3R2,PLS3,PCNA,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,PAPSS1,PSMC2,MITF,ELF5,TMEM143,DUSP10,TNFRSF18,NTN4,NEB,S100A13,THRB,CD55,KCNIP3,MARK1,CELSR2,NFE2L1,CR2,EZR,KLK6,ARFRP1,ANLN,PRKRA,IDH1,CLCN2,ZBTB7B,CDK1,RHEB,PLEKHB1,OPTN,IRX3,DPYSL3,HS6ST1,TRAM2,KCNMB4,MAP2,HOXA9,PRKCDBP,POMT1,MYL12B,MAFF,RUNX2,USH1C,LGALS3,RASA2,PDCL,PSMD7,SORBS3,RACGAP1,NCKAP1,CNTNAP2,DOCK11,FBLN1,DHRS3,IL18R1,PGAP1,ANO1,CORO1B,B4GALNT1,BMP2,TNS3,RB1,VASP,DAZAP1,TIMP1,IGF1R,SPIN4,GATA2,FRAS1,KIF13B,PAK2,PIM1,NTN1,WNT3A,PLCB2,ALDH3A2,PSMA5,CYP26B1,DPYSL5,PCDH1,TESK1,RGMB,SCRIB,EIF2AK1,TCF7,UNC45B,G2E3,PRX,SMN1,CDK5R1,RASGRP2,MAPKAPK2,MOSPD3,FA2H,COL13A1,PVRL2,PHLPP2,ITGA7,CSF1,PRPS2,ATP1B3,SEMA3A,CCNB2,NF2,HOXB7,FOXM1,P3H2,DGKA,TP53,P2RX7,ERBB2,RASGRP3,SLC7A2,STIL,EMP2,BCAP31,SDF4,PER2,IER3,TTC21B,PDGFA,TACC2,LMO4,PLCG2,LHX6,SRR,BCL6,PLK4,GYS1,CDH3,ESPN,NOTCH3,SCN2A,MINPP1,LMAN1,GM2A,DVL2,SULF2,SIRT1,CLCN3,TIMP2,MBP,AKT1,FIGNL1,S100A4,CCSAP,CDC20,PTGER4,ACO1,MYL12A,DAG1,PTGS2,DUOX1,RTN4RL1,PTPRJ,ATP1A1,IDE,PAFAH1B3,ABHD12,PSMD3,PTK7,ADAMTS14,CHMP4B,EFNA5,IRF7,RPL22,LTA4H,POMGNT2,FAM134B,CTDSP1,BIN1,COL9A3,DYRK3,CDH22,CD63,ADGRG1,CTSB,GNAL,MCTP2,GABRG2,SELL,PSMD10,JAG2,CRABP2,FZD6,PPP2R3A,SIRPA,NRP2,GBX2,ZDHHC21,CD109,FOXP2,CDK16,UBE2J1,TFAP2A,SGK1,ALDH7A1,HMGCL,SYK,CAMK2G,FAM134C,ATP2B1,TLE6,GCNT1,DUSP1,P2RX4,HES1,RHOA,PSMB4,PLAUR,CRIP2,PPARA,PRICKLE1,STMN3,COL7A1,FNDC3A,BCAR1,RNPEP,BBS2,DGKE,BCL10,PRDX4,CNOT2,DDAH1,SERPINA1,FAT4,TWSG1,SCG2,FGF18,E2F1,PGRMC1,PPP2R3C,PKD2,GAA,ACVR1,SSH1,LGR4,HSPG2,VANGL1,TMEM41B,ATP8A1,KLC2,CUL1,GATA3,PSME1,PLXNA1,CAMK1D,CCNB1,SEPT4,VASH1,PJA2,OAT,FAM101B,PICK1,NCS1,CHST2,TYMP,CYP1A1,CTGF,STIM1,IL31RA,FOSB,POLL,PIK3CA,IRF2,TACSTD2,ZBTB18,PACSIN1,LAMP2,SGCE,ACVR1C,CASP9,CDYL,MGAM,AURKB,CCNF,SAV1,LDB2,ZFAND5,ULK2,SFXN1,HLF,AREG,PLK2,TBX1,NKD1,LRIG1,BMP1,DHTKD1,EIF4EBP2,SERPINI1,SPRY4,UNC5B,TANC2,F2RL1,LZTS1,FGD1,DLAT,SEMA6B,KLF2,MRC2,INPPL1,CDKN1C,DGKQ,SLC25A27,KIF23,SLC1A3,NOTCH2,HERC6,APBA1,TNFRSF19,S100A2,KIAA1161,MECOM,CALR,DOPEY2,ITGA3,CYR61,BHLHE41,MSH2,PRKG1,SORL1,OSTF1,TNFRSF12A,CACNA1D,PIKFYVE,CTSD,DLX4,GPR161,RIMS2,TMED2,IGSF3,DNAI1,EPB41L5,GFPT1,SPATA20,KCNJ12,MMD,CALM1,AMER1,ANO6,DCHS1,WHSC1,VEZT,EPHA1,KDM3A,NFIB,RASA1,STX3,PDE11A,FAS,DGKH,MMP15,GABRD,NAB2,MATN2,FAM83D,PCDH19,SFMBT1,NR4A2,EFNA1,PER3,HOOK1,EHD1,IRF1,PLA2G4A,SPRED1,KIF3C,FOXO6,TCF25,ST14,THRA,RPS6KA1,IQGAP1,NDRG1,CAST,IRX4,EGR3,BCL2L1,FLT3,DDR1,CYP39A1,MNS1,EPM2A,CD46,NOV,APLP2,CCNA2,DOK4,CNNM4,CDKN1B,DAB2IP,PDE4D,EPHB4,LGMN,MED30,GPX4,SEMA3B,MYO5B,DMTN,UTRN,COX11,PRKCQ,SLC11A2,ATP1B1,PYGO1,ITPR3,ALCAM,FZD7,CMTM7,EPHA10,FYN,JAK1,NGFRAP1,STAT1,PPP1CB,KLF5,NRG1,RAB29,PRR15,CBX7,COBL,PRKAR1A,WASF3,PCOLCE,HAPLN3,JRKL,CENPI,EPS8,NES,PBX3,SEPP1,SPR,EFNB1,FGF19,TEAD3,ADGRB2,SIX4,RND1,SNTA1,E2F7,OXCT1,MGAT1,PTEN,FUT8,FJX1,CD9,ATP8B1,ERCC2,ERBB3,CITED2,MAP3K7,GFI1,TTPA,SPRY2,OSGIN1,MSH6,NCOA2,FARP2,PDGFC,TGIF1,RASGRF1,ARHGEF28,B3GNT2,TCFL5,FURIN,VAMP3,C1GALT1C1,DIAPH2,YES1,FOS,KIF11,GPLD1,CDK5RAP1,RGS9,TIMP3,DGCR2,CTNS,FGFR2,PRDX3,TBX18,RYK,SERPINB5,ERAP1,GRIN2D,GPER1,LRRK1,WDR62,FZD5,ARSB,NCAPG2,SLC25A38,MELK,RGMA,JARID2,EXPH5,EMX1,CASP3,UGT8,CRYM,UBE2Q1,PLAC1,MPP5,KIF2C,CACNB4,DNER,TMC1,HTR1D,EPCAM,HSF2,LRRC6,GRHL1,CDKL5,IMPAD1,DPYSL2,DLG1,AKR1B1,TRPC1,KIF22,ASH2L,RP2,MYH14,ARNT2,CTTN,BTBD3,IL1RAP,RASGRP1,SP5,CYP1B1,ATL1,SOD1,TRIM8,ASXL1,RNF165,ARHGDIB,EDNRA,MDK,CXXC4,GPRC5B,HPSE,TDRD7,TRIM45,APBA2,NRGN,PSMC1,PPP2R5D,CAPN1,NR2C2,PCSK5,GRN,SERPINE2,BVES,ETV5,CALM3,DUSP5,SPP1,CA2,LRRN2,FAM20C,OCRL,KCNN4,COL6A1,SUCO,PRKCI,EBF4,FNIP1,NPTN,SLC12A2,ETV7,CCDC88A,MDFI,ELK3,OXR1,SPA17,BTN3A2,VWA1,HMG20B,PDE5A,C3orf58,RANBP9,EGFR,FECH,GNAS,BCAR3,TSC1,ONECUT1,INSR,PLPP3,TMEM30A,UTP14C,ALPK3,EGFL7,PITPNA,DONSON,SHROOM2,JAK3,APOL2,COL16A1,RARG,KLF7,DRD1,DYNLRB1,SORBS1,PAX6,IL15,PSME2,HDAC11,SOD2,COL18A1,MRAS,TDRKH,OSR2,MICALL2,PHLDA1,EXT2,MXD1,SS18,KCTD15,ARTN,SETDB2,CYP4F11,KIF14,FRYL,SMO,DIXDC1,TWIST1,ECE1,NFKB2,F2R,LOXL1,HSPA2,FRS3,MAP3K3,SOAT1,PTPRU,OSTM1,GLO1,IGSF8,DUSP4,CD40,CDC25C,ARHGAP35,SOCS3,HSF4,ALDH5A1,BFSP1,BHLHB9,STAT6,PEX2,TLE1,PTBP3,OVOL1,SPTBN5,RCAN2,PLXND1,ABCA1,LIFR,ANXA3,GCLM,SORT1,ARHGEF11,CIT,ARHGEF7,POC1B,LRP4,TGFBR1,AES,COL4A5,NTAN1,SBF1,ITGA2B,HDAC9,KIF5B,TOP2A,MDM1,ADORA1,ADRBK1,LLGL2,BMP7,MYCL,TOX2,RRBP1,KIAA0319,ACTA2,ARVCF,TRIM3,MTURN,RPGR,MYO5A,ADAM17,WNT10B,ASPM,GCLC,NR4A1,RC3H2,RGCC,MBNL3,TTC7A,RUNX3,FAM73B,NDRG3,LEPR,FOXL1,MAP1B,LEMD2,CTSL,ARHGAP24,CD8A,SWAP70,DHRS2,PRCP,CTSV,SPINT2,CSGALNACT1,ARRB1,HOXB13,SOX8,ZMIZ1,PLOD3,AHR,L1CAM,ABCG1,NGEF |
| 3.743e-03 | -5.59 | LIN_MELANOMA_COPY_NUMBER_UP | MSigDB lists | LIN_MELANOMA_COPY_NUMBER_UP | 69 | 19 | 17758 | 2588 |
PSMB4,SALL4,ATP9A,IQGAP1,CDYL,MRPS35,MEST,ANO1,FGF19,CCND1,DNM1L,MITF,FAM63A,ECI2,RFX5,CEP41,NAGA,ARNT,CERS2 |
| 3.743e-03 | -5.59 | PID_VEGFR1_2_PATHWAY | MSigDB lists | PID_VEGFR1_2_PATHWAY | 69 | 19 | 17758 | 2588 |
PRKAA2,RHOA,AKT1,IQGAP1,PRKAA1,PIK3R1,CBL,PRKACA,MAPKAPK2,PLCG1,FYN,PTPRJ,CTNNB1,PAK2,DNM2,PIK3CA,MAPK11,ITGAV,GAB1 |
| 3.766e-03 | -5.58 | ITGB5 (integrin beta 5) | protein interactions | 3693 | 46 | 15 | 16036 | 2547 |
SNTA1,LTBP1,SPP1,KLK5,ITGA3,CYR61,EPS8,PIAS2,FHL2,PDIA3,ITGAV,ATP1B3,MERTK,LTBP3,SRSF9 |
| 3.767e-03 | -5.58 | GHANDHI_BYSTANDER_IRRADIATION_UP | MSigDB lists | GHANDHI_BYSTANDER_IRRADIATION_UP | 79 | 21 | 17758 | 2588 |
PLA2G4A,GCLM,MCTP1,SLC39A8,MCTP2,SAT1,SOD2,OSGIN2,DUSP5,ICAM1,RGS9,PTGS2,POPDC3,RNF128,SLC16A6,NFKBIZ,EPB41L4B,ATP6V1C1,PTGES,AHR,C9orf72 |
| 3.770e-03 | -5.58 | PEART_HDAC_PROLIFERATION_CLUSTER_DN | MSigDB lists | PEART_HDAC_PROLIFERATION_CLUSTER_DN | 74 | 20 | 17758 | 2588 |
GRN,CCNE2,PLK1,ZWINT,S100A11,TP53,EMP3,CUL1,POLD3,NUBP1,PLK4,AURKA,KNTC1,HMGA1,CCNB2,UBE2C,GFI1,CTBP1,USP16,RAD21 |
| 3.779e-03 | -5.58 | Integrin-mediated cell adhesion | WikiPathways | WP185 | 99 | 27 | 4455 | 729 |
SORBS1,AKT1,CAPN6,ARHGEF7,ITGA6,CAPNS1,MAPK4,TNS1,ILK,BCAR1,SEPP1,ITGA2B,CAPN2,PAK6,ZYX,RAC2,FYN,VASP,ITGB8,ITGA3,SHC3,ITGA7,PAK2,ITGAV,MAPK7,CAPN1,MAPK12 |
| 3.781e-03 | -5.58 | calcium ion binding | molecular function | GO:0005509 | 677 | 126 | 16491 | 2452 |
PLA2G4A,MYL9,DOC2A,LTBP1,SLC25A24,AGRN,CAPN12,REPS2,S100A11,SLC25A13,IQGAP1,RHBDL3,RET,DGKA,RASGRP3,SYTL4,DNER,REPS1,LTBP3,NCS1,SDF4,SYTL2,EPDR1,PLS3,CALM2,RCN1,CDH1,STIM1,NPNT,CABP1,SRR,CDH3,NOTCH3,S100A13,RASGRP1,SULF2,CHP1,GCA,KCNIP3,MCTP1,CELSR2,S100A4,CLSTN1,CBL,MCFD2,MYL12A,DAG1,LCP1,NIN,PLCH1,ENPP1,DUOX1,PLCG1,MMP17,GNPTAB,NKD1,BMP1,EFCAB14,CANT1,ANXA9,SYT13,TC2N,MYL12B,CAPN1,ANXA11,ANXA3,HSP90B1,PLSCR4,CDH22,MAN1A2,CALB2,MCTP2,LRP4,CALM3,EFHD2,NOTCH2,JAG2,NUCB2,S100A2,FBLN1,HPCAL4,PRRG4,PPP2R3A,CALR,CAPN2,FAM20C,MEGF8,NECAB3,DGKG,PLCB2,SYTL3,S100A6,SNED1,MYO5A,FBLN5,PCDH1,PLSCR1,TBC1D8B,RAPGEF2,CALM1,DCHS1,GRIN1,PLS1,CAPNS1,AIF1L,CDK5R1,RASGRP2,MMP15,GALNT3,NUCB1,SWAP70,FAT4,SYT7,CGREF1,MATN2,S100A5,DYSF,PCDH19,EGFL7,PKD2,LTBP2,MELK,ESYT2,PKD1L2,EHD1,TLL2 |
| 3.785e-03 | -5.58 | CH | pfam domains | PF00307 | 67 | 19 | 16629 | 2504 |
LMO7,GAS2L1,ASPM,ARHGEF7,IQGAP1,SYNE2,UTRN,PLS1,MICALL2,SPTB,LCP1,PLS3,SMTNL2,CLMN,LIMCH1,DIXDC1,SPTBN5,TAGLN2,IQGAP3 |
| 3.804e-03 | -5.57 | GSE17721_CTRL_VS_POLYIC_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_8H_BMDM_DN | 197 | 43 | 17758 | 2588 |
LZTFL1,CRYM,SERPINB9,CCNL1,BCL2L1,TRIB2,IER3,ADORA1,TIMP1,SH3BP1,LMO4,RANBP1,H2AFY,SNX16,CD70,MDFIC,CACNA1D,PTPRE,IL10RB,HSPA2,GFPT1,MOB4,GCA,MFI2,LAP3,LGALS8,PARD3B,IGSF8,ATP8B3,EDNRA,MAGED2,ENDOD1,PLCG1,RND3,CCDC6,FGF18,ITPR1,HDAC1,KLF5,HMGA1,MAP3K5,RBM43,E2F8 |
| 3.833e-03 | -5.56 | WOOD_EBV_EBNA1_TARGETS_UP | MSigDB lists | WOOD_EBV_EBNA1_TARGETS_UP | 110 | 27 | 17758 | 2588 |
GCLM,NQO1,AGPS,S100A4,CALM1,TFAP2C,CALM3,NCKAP1,PRKRA,EMP2,FBLN1,LGALS3BP,ICAM1,H1FX,CALM2,APOBEC3B,GNAS,SLCO4A1,DGCR2,CTSC,CCDC6,STAT1,OPN3,ITGAV,FHL1,CTSD,EPHX1 |
| 3.849e-03 | -5.56 | OTU | prosite domains | PS50802 | 15 | 7 | 11866 | 1802 |
OTUB2,OTUD5,YOD1,OTUD1,ZRANB1,OTUD6B,ALG13 |
| 3.861e-03 | -5.56 | ephrin receptor binding | molecular function | GO:0046875 | 27 | 10 | 16491 | 2452 |
FYN,ANKS1B,SIPA1L1,EPHA4,EFNA5,EFNA1,CBL,TIAM1,EFNB1,CDK5R1 |
| 3.863e-03 | -5.56 | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN | 186 | 41 | 17758 | 2588 |
FARP1,ST13,DNAJC3,CNOT8,PNPLA2,BLCAP,SEPP1,SNX9,APPBP2,IRF2,ABCD1,TNFRSF18,RFX5,TMEM8A,OSBPL7,PLCB2,HSPA2,UPF3A,KRT80,ING1,NRBF2,SHARPIN,ERP44,ERBB2IP,PRRC1,PRKRA,PNKD,RNF19B,SPNS3,RASGRP2,ATP13A2,DCTN6,CSNK1G1,CORO1C,TMEM30A,ARAP1,NFKBIZ,ARF6,L1CAM,RPS6KA3,ARHGEF4 |
| 3.863e-03 | -5.56 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP | 186 | 41 | 17758 | 2588 |
KLF2,ACACB,ZNF395,TSC22D3,XYLT1,EPHA4,TMX4,ARL4C,GATA3,BTN3A1,SLC7A2,TRIB2,FAM46C,DNAJB9,MARCH8,ADD3,MCF2L,SORL1,SGK1,IL17RA,SEMA3G,PTPRE,MYBL1,TRAM1,EEF1D,DUSP1,SUN2,WNT10B,PTGER4,CLSTN1,GRIN1,CR2,FOS,RASGRP2,IRS2,DTX4,PPP1CB,NR4A2,NR3C2,TOB1,ATMIN |
| 3.863e-03 | -5.56 | GSE10325_CD4_TCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_MYELOID_UP | 186 | 41 | 17758 | 2588 |
ST13,ENO2,ITGA6,ARL4C,DGKA,GATA3,NUCB2,DHRS3,LTBP3,DENND2D,TMEM63A,TGFBR3,MGAT4A,BDH1,MSH2,FAM102A,PIM1,MYBL1,MAST4,PIGC,SOD1,FBLN5,STAT4,SLC39A8,PIK3R1,SYNE2,TCF7,PRKCQ,ESYT1,PLEKHB1,OPTN,TXK,SFXN1,AMZ2,PLCG1,LDLRAP1,LRIG1,INPP4B,APBA2,TBC1D4,DOCK9 |
| 3.866e-03 | -5.56 | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | 231 | 49 | 17758 | 2588 |
RBM24,SCD5,CALB2,COL4A5,IL27RA,PLAC1,EGR3,SYTL4,CCNB1,TMPRSS4,ZNF385B,IL17RB,TOP2A,ADD3,IGF1R,ZNRF2,NPNT,FRAS1,SGK3,ADCK2,ATRNL1,PIKFYVE,MYBL1,TIAM1,TIPARP,CPE,SUSD3,LAMP2,CELSR2,PRSS23,AMFR,PIK3R1,SYBU,PARP4,TFAP2C,BLVRA,PLIN5,IRX3,DDAH1,TMEM164,AREG,MAP2,NAB2,LRIG1,RAB31,GLA,STARD13,CBX5,ISOC1 |
| 3.889e-03 | -5.55 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | MSigDB lists | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | 126 | 30 | 17758 | 2588 |
DOCK4,KIF3C,KIF20A,KLC2,TP53,HMG20B,KIF23,GATA3,RACGAP1,PRKAR2B,KIF2C,DOCK5,PRKACA,KIF26A,KIF11,KIF5B,WEE1,GATA2,KLC3,IRF2,HDAC1,KIF22,IRF7,AK3,CBX5,MAFF,IRF1,DOCK9,EHD1,PRKAR1A |
| 3.901e-03 | -5.55 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_DN | 175 | 39 | 17758 | 2588 |
PNISR,TRAPPC10,AASS,CIT,CAST,NDC80,NUCB2,KBTBD11,PSIP1,ZFYVE16,ENTPD4,ADD3,PRICKLE3,FRYL,COL6A1,CLDN4,PLEKHF1,NFU1,NFKB2,CD55,SH3BGRL,FHL2,BNIP3L,MGAM,UBAC1,KIAA1109,FUCA1,WDR19,NOD2,PPP1CB,NXPH4,ALPK3,LRRK1,REEP4,NR3C2,NDST3,CBX7,CBX4,RAD21 |
| 3.901e-03 | -5.55 | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | 175 | 39 | 17758 | 2588 |
MAN2B2,DYNLRB1,TPRN,ARHGEF11,UBASH3B,GALNT12,ITGA6,ASAH1,FAM78A,SNN,TRIB2,EPS8L2,C16orf74,ABCA2,CD70,ETHE1,DLG3,CITED2,CLIP2,FLOT2,ALS2CL,C9orf72,SLC16A5,KCTD3,S100A6,DUSP1,MMD,KIFC2,PQLC3,LDB2,RNPEP,FOS,TYSND1,SOCS3,TXK,BMP1,NFKBIZ,ZMIZ1,TOB1 |
| 3.901e-03 | -5.55 | GSE29618_BCELL_VS_MDC_UP | MSigDB lists | GSE29618_BCELL_VS_MDC_UP | 175 | 39 | 17758 | 2588 |
KLF2,HECA,ZNF395,CKAP2,TSC22D3,MCTP2,RASGRP3,ETS1,FAM46C,CDK14,ADD3,CD22,PLCG2,VAT1,TSPAN13,PIKFYVE,RASGRP1,TUBA4A,SYPL1,SGCE,EZR,CYFIP2,C18orf8,OPTN,STK17A,RASGRP2,ARHGAP24,BTG1,BANK1,SWAP70,ITPR1,FAM3C,RYK,TLE1,CLMN,PIK3C2B,TTC9,CD81,KLF7 |
| 3.901e-03 | -5.55 | MTOR_UP.V1_DN | MSigDB lists | MTOR_UP.V1_DN | 175 | 39 | 17758 | 2588 |
LTBP1,KLF2,SLC2A4,BACE1,WDTC1,PDIA5,PHF1,H1FX,PDGFA,ARTN,SLC44A1,CRY2,ARL4D,NCAM1,SCARA3,MOXD1,CPE,SULT2B1,OSGIN1,FAH,DUSP1,PRSS23,ADCK3,PTGER4,B3GALNT2,BBS2,IRS2,TBC1D17,CTNS,PDLIM3,NR1D2,OSMR,ICOSLG,WBSCR27,LIFR,ABCA1,CSRP2,PHC1,XDH |
| 3.912e-03 | -5.54 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN | 164 | 37 | 17758 | 2588 |
DDX58,ACACB,IL15,TMEM217,PARP14,HAPLN3,GMPR,HERC5,SAMD9,CD274,HERC6,TP73,OTUD1,FBXO7,IFIT1,OAS3,FRS3,MX1,RIPK2,PLSCR1,COQ10B,SAT1,ZSCAN12,PTGS2,PI4K2B,TMEM54,C19orf66,ZNF214,SECTM1,STAT1,NFKBIZ,IRF7,CMPK2,IFIH1,GLCCI1,CSRP2,IRF1 |
| 3.913e-03 | -5.54 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | 341 | 68 | 17758 | 2588 |
CCNE2,SPC25,TCTN2,NDRG1,CTDSPL,PTTG1,RHBDL3,TDRKH,NUF2,PLXNA1,PHLDA1,EMP2,FAM46C,NCS1,KIAA1147,PDGFA,WEE1,CCNA2,UBE2T,ALDH1A3,PLK4,KIF22,ECE1,PTPRE,TIPARP,ETV4,IL1RAP,TUBA4A,HN1L,PBK,EZR,PKMYT1,GINS4,SFXN1,CDCA4,ZNF367,E2F8,CCM2,ETV5,ARL4C,KIF23,TGFBR1,ISYNA1,LBR,E2F7,SPIN4,KCNN4,RANBP1,MSH2,CKS1B,BUB1,PIM1,CITED2,MSH6,SUN2,FADS2,ZWINT,ADCK3,MYBL2,FOS,RASGRP2,SLCO4A1,TIMP3,SLC6A6,PELI2,ARRB1,MELK,EHD1 |
| 3.926e-03 | -5.54 | Focal adhesion | KEGG pathways | ko04510 | 207 | 47 | 6908 | 1076 |
MYL9,PPP1R12A,ITGA6,XIAP,ERBB2,COL4A5,PDGFB,ITGA2B,PDGFA,CAPN2,PAK6,CCND1,SPP1,ZYX,RAC2,VASP,IGF1R,CTNNB1,ITGB8,ITGA3,SHC3,PTEN,COL6A1,PAK2,PIK3CA,PIK3CD,PPP1CA,TLN2,PDGFC,RASGRF1,RHOA,COL6A2,AKT1,PIK3R1,ILK,ELK1,BCAR1,MYL12A,EGFR,ARHGAP35,PGF,FYN,ITGA7,MYLK,PPP1CB,ITGAV,MYL12B |
| 3.926e-03 | -5.54 | Focal adhesion | KEGG pathways | hsa04510 | 207 | 47 | 6908 | 1076 |
MYL9,PPP1R12A,ITGA6,XIAP,ERBB2,COL4A5,PDGFB,ITGA2B,PDGFA,CAPN2,PAK6,CCND1,SPP1,ZYX,RAC2,VASP,IGF1R,CTNNB1,ITGB8,ITGA3,SHC3,PTEN,COL6A1,PAK2,PIK3CA,PIK3CD,PPP1CA,TLN2,PDGFC,RASGRF1,RHOA,COL6A2,AKT1,PIK3R1,ILK,ELK1,BCAR1,MYL12A,EGFR,ARHGAP35,PGF,FYN,ITGA7,MYLK,PPP1CB,ITGAV,MYL12B |
| 3.938e-03 | -5.54 | phosphatidylinositol-mediated signaling | biological process | GO:0048015 | 139 | 33 | 16441 | 2455 |
TNRC6C,GATA3,NRG2,ERBB2,PHLPP1,PDGFB,CA8,FGF19,NCS1,PDGFA,IGF1R,PTEN,PIK3CA,CDKN1B,PIK3CD,ERBB3,RHOA,AKT1,NR4A1,CASP9,PIK3R1,EZR,AGO4,EGFR,IRS2,PLCH1,FYN,FGFR2,PHLPP2,FGF18,PIK3C2B,NRG1,GAB1 |
| 3.945e-03 | -5.54 | central_nervous_system-third_ventricle-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-third_ventricle-other-rosette-forming_glioneuronal_tumour | 12 | 6 | 17775 | 2585 |
GNAS,AKT1,IDH1,EGFR,RET,PIK3CA |
| 3.945e-03 | -5.54 | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma | 12 | 6 | 17775 | 2585 |
GNAS,CTNNB1,EGFR,AMER1,TP53,PRKAR1A |
| 3.946e-03 | -5.54 | intracellular lipid transport | biological process | GO:0032365 | 19 | 8 | 16441 | 2455 |
PRKAA2,ACACB,LDLRAP1,PRKAG2,CPT2,NPC2,ABCA1,ABCG1 |
| 3.952e-03 | -5.53 | PURINE_RIBONUCLEOTIDE_BINDING | MSigDB lists | PURINE_RIBONUCLEOTIDE_BINDING | 203 | 44 | 17758 | 2588 |
GALK1,TNK1,ACVR1,DYRK3,PINK1,PEX6,ABCG2,TP53,TGFBR1,ABCD4,DAPK2,CDKL5,RALB,PRKCI,ABCA2,MSH2,DAPK1,PIM1,MSH6,SMC4,ABCC1,SEPHS1,MX1,MARK1,GCLC,SEPT6,PIF1,MAP3K6,STK17B,RHEB,DGKE,RHOB,STK17A,RND3,ACVRL1,STK38,ATP7B,PPP2R4,ABCB1,GEM,MAP3K5,ARF6,DMPK,ABCG1 |
| 3.952e-03 | -5.53 | V$FOX_Q2 | MSigDB lists | V$FOX_Q2 | 203 | 44 | 17758 | 2588 |
CTHRC1,FARP1,CPEB4,CHCHD7,SLC20A1,NEO1,SCML1,FOXP2,ITGA3,VASN,NECAB3,LMO4,ZIC5,MITF,H2AFY,TWIST1,KLF9,NCAM1,NTN1,MYT1,BTBD3,MED22,CYP26B1,TGIF1,SMARCA2,SPATA18,SLC39A8,PRKAR2B,RAB3IP,H2AFV,EBF2,GABARAPL1,SWAP70,KLF12,COL13A1,NEIL3,NR4A3,PPP1CB,ADAMTS14,EIF4EBP2,NRG1,EFNA1,TOB1,RGMA |
| 3.955e-03 | -5.53 | response to oxidative stress | biological process | GO:0006979 | 339 | 69 | 16441 | 2455 |
CASP3,SLC25A24,TXN,NQO1,EPAS1,SOD2,TP53,HDAC6,SDC1,P4HB,DNM2,AKR1B1,SCARA3,CYP1B1,GPX4,SIRT1,PPIF,SOD1,AKT1,NFE2L1,SLC11A2,PRKRA,IDH1,PTGS2,DUOX1,ALDH3B1,NEIL1,STK26,AREG,RCAN2,RGS14,GAB1,ARNT,GCLM,KLF2,PINK1,TRAF2,PRKAA1,ETV5,GSTP1,ETS1,SEPP1,PSIP1,PDCD10,CST3,SELK,ERCC2,MAPK7,NDUFA12,DUSP1,PRODH,GCLC,MICB,OXR1,ERO1A,FOS,RHOB,IL1R1,BTG1,PRDX3,DHRS2,NR4A3,OSER1,PKD2,NR4A2,MAP3K5,CPEB2,MELK,EGLN1 |
| 3.955e-03 | -5.53 | MHCCLASSI | prints domains | PR01638 | 9 | 5 | 4759 | 661 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 3.955e-03 | -5.53 | HLA-C (major histocompatibility complex, class I, C) | protein interactions | 3107 | 64 | 19 | 16036 | 2547 |
NEK4,TCTN2,HLA-E,HLA-F,ITGA6,FBXO6,POMGNT1,PRRG4,HLA-A,CALR,HLA-B,TAPBP,CD8A,TMEM30A,FAM3C,NETO2,FAM213A,ATP1B3,HLA-C |
| 3.957e-03 | -5.53 | neural tube development | biological process | GO:0021915 | 155 | 36 | 16441 | 2455 |
CTHRC1,GRHL2,ST14,SDC4,RAB23,NCKAP1,PRKACA,STIL,FZD6,GBX2,VASP,LMO4,SMO,TWIST1,MAP3K7,WNT3A,DVL2,HES1,TGIF1,SALL4,DCHS1,PRICKLE1,KIF20B,SCRIB,ARHGAP35,BCL10,TSC1,SHROOM3,PTK7,TRAF3IP1,SPINT2,PKD2,PLOD3,RARG,COBL,FOXA1 |
| 3.959e-03 | -5.53 | INPP5D (inositol polyphosphate-5-phosphatase D) | protein interactions | 3635 | 55 | 17 | 16036 | 2547 |
INPPL1,TRIP10,INPP5D,UBASH3B,PIK3R1,XIAP,CBL,FLT3,SH3KBP1,PLCG1,JAK1,CD22,ARAP1,LRRK1,JAK3,SYK,GAB1 |
| 3.959e-03 | -5.53 | SORBS3 (sorbin and SH3 domain containing 3) | protein interactions | 10174 | 55 | 17 | 16036 | 2547 |
INPPL1,AKT1,FLOT1,SORBS3,SYP,VARS2,CBL,ZBTB7B,ADAMTSL4,SH2D4A,CPNE2,UBE2T,PAK2,ADAM15,ARNT2,NOTCH3,DVL2 |
| 3.960e-03 | -5.53 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | MSigDB lists | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | 105 | 26 | 17758 | 2588 |
ADAM17,AKT1,NR4A1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,PHLPP1,ITPR3,CBL,PRKACA,CDK1,EGFR,SH3KBP1,CALM2,PLCG1,ADRBK1,PTEN,LRIG1,PIK3CA,CDKN1B,SPRY2,GAB1,PRKAR1A |
| 3.963e-03 | -5.53 | BURTON_ADIPOGENESIS_7 | MSigDB lists | BURTON_ADIPOGENESIS_7 | 50 | 15 | 17758 | 2588 |
CCND1,TIMP2,NQO1,SERPINE2,TIMP1,IFITM3,IL6ST,S100A4,PBX3,TAGLN2,TINAGL1,CTTN,CPE,H2AFV,S100A6 |
| 3.963e-03 | -5.53 | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | MSigDB lists | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | 50 | 15 | 17758 | 2588 |
CDKN2C,WEE1,CCNA2,FOXM1,CDC20,E2F1,CKS1B,AURKA,KIF2C,RNASEH2A,UBE2C,KIF11,BARD1,CDK1,PRIM1 |
| 3.966e-03 | -5.53 | ciliary part | cellular component | GO:0044441 | 304 | 62 | 17570 | 2579 |
TTC8,CFAP74,DYNLRB1,KIF3C,PIFO,TCTN2,POC1B,KLC2,C5orf30,SEPT4,PRKACA,MAP1LC3B,DNAH3,IFT27,DHRS3,MNS1,SSX2IP,TTC21B,KIF5B,INPP5E,SCNN1A,DNAH6,SMO,KLC3,TUBG1,RP2,CNGA1,RPGR,GPR161,DNAI1,SPEF2,LCA5,CASK,AKT1,CEP89,CFAP46,B9D2,FOPNL,CCSAP,CYS1,SPA17,EZR,PRKAR2B,RAB3IP,AKAP3,NPHP3,BBS2,CEP162,DZIP1L,PROM1,PHLPP2,WDR19,TRAF3IP1,SPTBN5,SSNA1,PKD2,CFAP20,CEP41,DRD1,EHD1,PRKAR1A,PROM2 |
| 3.972e-03 | -5.53 | basement membrane | cellular component | GO:0005604 | 94 | 24 | 17570 | 2579 |
TIMP2,CASK,AGRN,HSPG2,ITGA6,P3H2,COL18A1,VWA1,COL7A1,COL4A5,LOXL2,ERBB2IP,FBLN1,DAG1,TIMP3,TIMP1,NPNT,FRAS1,CST3,MATN2,DLG1,NTN4,NTN1,LOXL1 |
| 3.974e-03 | -5.53 | V$ARNT_02 | MSigDB lists | V$ARNT_02 | 237 | 50 | 17758 | 2588 |
LAMP1,AVPI1,ARMCX3,CPEB4,ALDH6A1,FAM134A,TRAPPC8,PKN1,SNN,NUP62CL,GNB2,VPS26A,CDKN2C,ICAM5,BHLHE41,FAM13B,BAX,TRIM3,SGK1,SNX16,MANF,NPTN,EPB41L4B,ARMCX6,TUBA4A,SIRT1,HPS3,USP31,SNTB2,CBX6,OGDHL,CDK5R1,PTPRF,GNAS,TIMM8A,NGFRAP1,HNRNPH2,KBTBD2,HOXA9,PRPS2,RAB31,FAM117A,KLF11,HMGA1,GLA,C1orf43,ATP6V1C1,CBX5,MAFF,RNF146 |
| 3.977e-03 | -5.53 | FU | smart domains | SM00261 | 18 | 8 | 9131 | 1455 |
INSR,IGF1R,FRAS1,FURIN,ERBB2,ERBB3,EGFR,PCSK5 |
| 3.985e-03 | -5.53 | endochondral ossification | biological process | GO:0001958 | 27 | 10 | 16441 | 2455 |
GNAS,INPPL1,RUNX2,HSPG2,COL13A1,IMPAD1,NAB2,FGF18,CSGALNACT1,PHOSPHO1 |
| 3.985e-03 | -5.53 | replacement ossification | biological process | GO:0036075 | 27 | 10 | 16441 | 2455 |
GNAS,INPPL1,RUNX2,HSPG2,COL13A1,IMPAD1,FGF18,NAB2,CSGALNACT1,PHOSPHO1 |
| 3.985e-03 | -5.53 | cell differentiation involved in embryonic placenta development | biological process | GO:0060706 | 27 | 10 | 16441 | 2455 |
E2F7,GRHL2,AKT1,ST14,SPINT2,PLK4,FZD5,E2F8,MDFI,SOCS3 |
| 3.985e-03 | -5.53 | V$PU1_Q6 | MSigDB lists | V$PU1_Q6 | 220 | 47 | 17758 | 2588 |
SEMA6B,GRIK2,STRN4,GATA3,C6orf106,IL18,PKN1,FAM81A,DPP8,SIRPA,H1FX,IRF2BPL,ST5,SESN3,ADORA1,PPP1R10,RINL,ATP5H,FUT8,ADAM15,TWIST1,RAB20,PPP1CA,CNOT6L,NFKB2,PLCB2,DNAI1,RHOA,TFAP2C,PPP1R14C,GLT8D2,TCN2,ONECUT1,FYN,ACVRL1,PTK7,CSF1,STAT6,CTSA,SP6,PIEZO1,SLC27A3,FOXA1,JARID2,PCSK5,ARHGEF4,NR2C2 |
| 3.988e-03 | -5.52 | TAGHAVI_NEOPLASTIC_TRANSFORMATION | MSigDB lists | TAGHAVI_NEOPLASTIC_TRANSFORMATION | 12 | 6 | 17758 | 2588 |
MAP3K3,AGRN,GRHL1,PDGFB,MCF2L,FOSB |
| 3.988e-03 | -5.52 | MODULE_190 | MSigDB lists | MODULE_190 | 12 | 6 | 17758 | 2588 |
LTBP1,NOV,IGFBP2,CTGF,IGFBP6,CYR61 |
| 3.999e-03 | -5.52 | NOD1/2 Signaling Pathway | REACTOME pathways | R-HSA-168638 | 31 | 11 | 8202 | 1235 |
IRAK1,RIPK2,TAB3,ITCH,CASP9,NOD2,MAPK11,MAPK13,MAP3K7,CASP4,MAPK12 |
| 4.003e-03 | -5.52 | TMEM63A (transmembrane protein 63A) | protein interactions | 9725 | 3 | 3 | 16036 | 2547 |
LGALS3,FAM189A2,LGALS8 |
| 4.003e-03 | -5.52 | Nek2 (NIMA (never in mitosis gene a)-related expressed kinase 2) | protein interactions | 18005 | 3 | 3 | 16036 | 2547 |
ACAD8,PPP1R2,NEK2 |
| 4.003e-03 | -5.52 | ARMCX5 (armadillo repeat containing, X-linked 5) | protein interactions | 64860 | 3 | 3 | 16036 | 2547 |
APPBP2,DCP2,TP53 |
| 4.003e-03 | -5.52 | TMEM245 (transmembrane protein 245) | protein interactions | 23731 | 3 | 3 | 16036 | 2547 |
FBXO6,LYPD3,LYPD6 |
| 4.003e-03 | -5.52 | ARL14EP (ADP-ribosylation factor like GTPase 14 effector protein) | protein interactions | 120534 | 3 | 3 | 16036 | 2547 |
FAF2,SETDB2,PNKD |
| 4.003e-03 | -5.52 | SLC36A1 (solute carrier family 36 (proton/amino acid symporter), member 1) | protein interactions | 206358 | 3 | 3 | 16036 | 2547 |
PTEN,LGALS8,PTTG1 |
| 4.003e-03 | -5.52 | Khdrbs1 (KH domain containing, RNA binding, signal transduction associated 1) | protein interactions | 20218 | 3 | 3 | 16036 | 2547 |
TRAF2,SH3KBP1,RASA1 |
| 4.003e-03 | -5.52 | ATP11A (ATPase, class VI, type 11A) | protein interactions | 23250 | 3 | 3 | 16036 | 2547 |
NPDC1,TMEM30A,PICK1 |
| 4.003e-03 | -5.52 | Cbl (Casitas B-lineage lymphoma) | protein interactions | 12402 | 3 | 3 | 16036 | 2547 |
SYK,EGFR,SH3KBP1 |
| 4.003e-03 | -5.52 | Rab33b (RAB33B, member RAS oncogene family) | protein interactions | 19338 | 3 | 3 | 16036 | 2547 |
TGFBR1,ACVR1,CALM1 |
| 4.003e-03 | -5.52 | E1A (alternative splicing utilizing nonconserved sites may produce additional proteins) | protein interactions | 2652980 | 3 | 3 | 16036 | 2547 |
CDKN1B,RB1,CTBP1 |
| 4.003e-03 | -5.52 | MORC3 (MORC family CW-type zinc finger 3) | protein interactions | 23515 | 3 | 3 | 16036 | 2547 |
KPNA2,ROR1,RAD23A |
| 4.012e-03 | -5.52 | response to calcium ion | biological process | GO:0051592 | 113 | 28 | 16441 | 2455 |
PPIF,SCN5A,SLC25A24,SLC25A13,DMTN,IQGAP1,CALM1,GRIN1,CALM3,P2RX7,ITPR3,FOS,SDC1,RASGRP2,GPLD1,CCND1,CALM2,CPNE2,KCNMB4,STIM1,HTT,FOSB,TRPC1,ALG2,TRPC3,PTGES,ANXA11,DUSP1 |
| 4.016e-03 | -5.52 | BASSO_B_LYMPHOCYTE_NETWORK | MSigDB lists | BASSO_B_LYMPHOCYTE_NETWORK | 137 | 32 | 17758 | 2588 |
BIN1,HLA-E,NDRG1,TGOLN2,IL27RA,ITPR2,CCNB1,ZYX,PCNA,PSMD1,CCNA2,SP100,TUBG1,ARVCF,MDFIC,ETHE1,PLCB2,DDB2,SUN2,S100A4,SAT1,LITAF,TEP1,CASP4,CDK1,MYL12A,PRDX4,MAP1B,SLC25A4,PRDX3,ITPR1,SLC4A3 |
| 4.029e-03 | -5.51 | GSE17721_CTRL_VS_CPG_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_8H_BMDM_UP | 192 | 42 | 17758 | 2588 |
SLC25A13,TGFBR1,MGST2,COMMD5,LTBP3,XPR1,H1FX,TM9SF2,SLC16A6,TMEM51,PCYOX1,ABCA2,FAM63A,TRIM3,GYS1,ADAM15,HMGCL,IQGAP3,CNOT6L,PHKA2,MPHOSPH9,MED22,HP1BP3,MOSPD2,KIF20A,UXT,BNIP3L,FBXO8,FAM73B,SNAPC2,CDC25C,OSBPL2,MTFMT,PLA2G15,PRPS2,PRKCDBP,FAM117A,PLD1,CCNB2,MYL12B,CPPED1,FAM134B |
| 4.029e-03 | -5.51 | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN | 192 | 42 | 17758 | 2588 |
GRN,HECA,BMF,PINK1,GPR107,RPS6KA1,CCM2,SMARCAL1,EFHD2,IL27RA,FAM78A,GNB2,KIAA1147,CXCL16,PIK3AP1,WDR44,MGAT4A,SGK3,SORL1,PIK3CD,SYK,CTDSP2,MAP3K3,SUN2,ORAI2,TRIM8,TACC1,TTC7A,RUNX3,ILK,ADRBK2,FUCA1,NCOA3,PVRL2,ATXN7L3,SH2D3C,STK38,ARRB1,ZDHHC7,CTNND1,LTBP2,AKNA |
| 4.029e-03 | -5.51 | GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_UP | MSigDB lists | GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_UP | 192 | 42 | 17758 | 2588 |
RMND5A,CMAS,CDKN1C,HLA-E,SDC4,KIF23,NDRG2,BCL2L1,OAT,MNS1,PLS3,BTG3,ADRBK1,MKRN3,ATP13A3,KLF3,FAM63A,PIK3CD,CNGA1,MPHOSPH9,MDFI,SEC23A,CLCN3,CXXC5,ASXL1,ASPM,MPP1,GLO1,KDM3A,FAS,ANKRD10,CD8A,NR1D2,PRDX3,ITPR1,MAOA,GRIN2D,SLC27A1,ACADM,ITGAV,TRAF5,RRAGD |
| 4.029e-03 | -5.51 | GSE3982_MAST_CELL_VS_TH1_DN | MSigDB lists | GSE3982_MAST_CELL_VS_TH1_DN | 192 | 42 | 17758 | 2588 |
CDS2,PPP1R2,FOXM1,NUAK1,DNAJC3,CTDSPL,SDC4,MORC4,ETS1,SPSB1,APOBEC3B,NAPG,PCNA,MSH2,SERINC2,KNTC1,LMAN1,HP1BP3,PLK1,TDP1,TAF5,SEPT6,C3orf52,AK4,KIF20B,GGH,PDK3,PRRC1,POLD3,NPDC1,STEAP1,GINS4,OPTN,SFXN1,MID1IP1,PRDX3,RBL1,SH2D3C,SECTM1,AURKA,NCAPG2,CSRP2 |
| 4.029e-03 | -5.51 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | 192 | 42 | 17758 | 2588 |
CASP3,RUNX2,LGALS3,SEC61G,SLC25A13,PLA2G16,BARD1,CARD10,B4GALNT1,BTG3,UBE2T,MGAT1,RRBP1,CD70,F2R,SULT2B1,C12orf75,MED30,PSMA5,OSGIN1,CPD,SUSD3,MLEC,SEC61B,FHL2,LITAF,VEZT,LRRC1,RNPEP,FRMD4B,GABARAPL1,AHRR,NUCB1,ENPP1,CD8A,RYK,PKD2,TTC39C,HOOK1,CHPT1,AHR,EHD1 |
| 4.029e-03 | -5.51 | GSE27786_BCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_BCELL_VS_MONO_MAC_DN | 192 | 42 | 17758 | 2588 |
GSDMD,FARP1,HJURP,MPZL1,FAM160B1,LGI3,TMPRSS4,TEAD3,CYP26A1,VASP,MCF2L,FAM63A,SMO,PRC1,RP2,IQGAP3,ACAD8,CITED2,SNED1,CAMK2G,ASPM,CDC20,CCDC34,CAPNS1,GGH,PKMYT1,EPHA1,PRKRA,LHFPL2,RNF19B,ZNF469,OPTN,KLHL2,MID1IP1,RBM47,CORO1C,NETO2,ARRB1,SERPINB6,SPRY4,E2F8,ARHGEF4 |
| 4.035e-03 | -5.51 | WWE-dom | interpro domains | IPR004170 | 12 | 6 | 18293 | 2672 |
PARP12,TIPARP,PARP14,RNF146,DDHD2,DTX4 |
| 4.052e-03 | -5.51 | FERM_central | interpro domains | IPR019748 | 50 | 15 | 18293 | 2672 |
FRMPD3,EPB41L5,PLEKHH2,FARP1,JAK1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 4.060e-03 | -5.51 | fibrosarcoma | COSMIC cancer mutations | fibrosarcoma | 32 | 11 | 17775 | 2585 |
GNAS,CDKN2C,RB1,SS18,CTNNB1,CDH1,PTEN,PIK3CA,TP53,IDH1,EGFR |
| 4.060e-03 | -5.51 | SUMO4 (small ubiquitin-like modifier 4) | protein interactions | 387082 | 78 | 22 | 16036 | 2547 |
ENO2,NR3C1,PDIA3,DNAJB11,ARHGDIB,IDH1,GSTP1,FOS,LMNA,VCP,PRDX4,CALR,TOP2A,PAFAH1B3,PRDX3,SPINT2,NFKBIA,PSMC2,STAT1,TFAP2A,ACADM,PDIA6 |
| 4.070e-03 | -5.50 | polysaccharide catabolic process | biological process | GO:0000272 | 23 | 9 | 16441 | 2455 |
CALM2,PGM1,GAA,CALM1,MGAM,PYGL,CALM3,PHKA2,PHKG2 |
| 4.070e-03 | -5.50 | mating behavior | biological process | GO:0007617 | 23 | 9 | 16441 | 2455 |
THRB,GRN,APLP2,PTEN,THRA,HEXB,GRIN1,UBE2Q1,DRD1 |
| 4.070e-03 | -5.50 | negative regulation of muscle contraction | biological process | GO:0045932 | 23 | 9 | 16441 | 2455 |
DOCK4,PTGS2,SOD1,ADORA1,ADRBK1,PRKG1,PDE5A,CALCRL,DOCK5 |
| 4.070e-03 | -5.50 | cellular component maintenance | biological process | GO:0043954 | 23 | 9 | 16441 | 2455 |
CAMSAP3,ITGA3,PLEKHA7,PKP2,CTTN,ITPKA,TANC1,SHROOM2,PICK1 |
| 4.072e-03 | -5.50 | VEGFR1 specific signals | Pathway Interaction DB | vegfr1_pathway | 29 | 13 | 2227 | 480 |
PGF,CALM2,PLCG1,AKT1,CALM1,PIK3R1,PIK3CA,CALM3,CBL,PRKACA,GAB1,RASA1,NRP2 |
| 4.072e-03 | -5.50 | regulation of mitotic nuclear division | biological process | GO:0007088 | 134 | 32 | 16441 | 2455 |
DLGAP5,CIT,PTTG1,PDGFB,NPM2,RB1,IGF1R,PTEN,BMP7,NEK2,BUB1,KNTC1,PLK1,CDC20,RGCC,VPS4B,NUSAP1,KIF20B,PKMYT1,ANLN,BORA,KIF11,CDC25C,INSR,FGFR2,CDCA5,AURKA,CHMP4B,CENPE,UBE2C,MAD2L1BP,ESPL1 |
| 4.077e-03 | -5.50 | MAPK signaling pathway | WikiPathways | WP382 | 163 | 40 | 4455 | 729 |
CASP3,TAOK2,TRAF2,RASA2,TP53,TGFBR1,MAPK4,MRAS,PRKACA,PDGFB,DUSP5,RAC2,PAK2,DUSP10,TMEM37,MAP3K7,MAPK7,RASGRP1,DUSP1,AKT1,ACVR1C,NR4A1,CASP9,ELK1,DUSP4,FOS,MAP3K6,RASA1,EGFR,FAS,MAPKAPK2,IL1R1,CASP7,MAP3K11,ARRB1,MAPK13,MAP3K5,HSPB1,RPS6KA3,MAPK12 |
| 4.079e-03 | -5.50 | WOO_LIVER_CANCER_RECURRENCE_UP | MSigDB lists | WOO_LIVER_CANCER_RECURRENCE_UP | 100 | 25 | 17758 | 2588 |
CCNI,QSOX1,ENO2,PLAUR,SOX9,NOTCH2,JAG2,DUSP4,DDR1,DPYSL3,PDGFA,CTGF,FGFR2,DPYSL2,BHLHE41,CSGALNACT1,FGD6,TACSTD2,HMGA1,GEM,ARHGAP4,SGCB,S100A6,MAPK12,LAMP3 |
| 4.086e-03 | -5.50 | phosphatidylinositol binding | molecular function | GO:0035091 | 194 | 43 | 16491 | 2452 |
MTM1,ARAP3,IQGAP1,RACGAP1,PLD2,ITPR2,APBA1,SNX9,FAM21C,ZFYVE9,SYTL2,ZFYVE16,SNX13,WDFY1,SNX18,MCF2L,PASK,SGK3,PLEKHF1,SNX16,DAB2IP,TTPA,SNX10,CCDC88A,SNX7,SNX8,ARAP2,MARK1,AKT1,AMER1,ITPR3,SNX12,LDLRAP1,WIPI1,ITPR1,ARAP1,PIK3C2B,PLD1,WDR45B,NRGN,PXDC1,SNX30,ESYT2 |
| 4.094e-03 | -5.50 | PURINE_NUCLEOTIDE_BINDING | MSigDB lists | PURINE_NUCLEOTIDE_BINDING | 209 | 45 | 17758 | 2588 |
GALK1,TNK1,DYRK3,ACVR1,PINK1,PEX6,TP53,ABCG2,TGFBR1,AIFM2,ABCD4,DAPK2,RALB,CDKL5,DAPK1,ABCA2,MSH2,PRKCI,PIM1,MSH6,SMC4,ABCC1,SEPHS1,MX1,MARK1,GCLC,SEPT6,PIF1,MAP3K6,STK17B,RHOB,RHEB,DGKE,STK17A,RND3,ACVRL1,ATP7B,STK38,PPP2R4,ABCB1,GEM,MAP3K5,ARF6,ABCG1,DMPK |
| 4.099e-03 | -5.50 | cellular polysaccharide biosynthetic process | biological process | GO:0033692 | 40 | 13 | 16441 | 2455 |
PGM1,B3GNT2,UGP2,AKT1,CSGALNACT1,GYS1,PGM2L1,NANS,B4GAT1,EXT2,PHKG2,EPM2A,PER2 |
| 4.113e-03 | -5.49 | positive regulation of endopeptidase activity | biological process | GO:0010950 | 150 | 35 | 16441 | 2455 |
CASP3,NKX3-1,DAP,PSME2,TRAF2,RET,PSME1,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,DAPK1,BAX,CDKN1B,WNT3A,EGLN3,F2R,SIRT1,RHOA,ACVR1C,CASP9,SLC11A2,BCL2L13,CYFIP2,VCP,FAS,BCL10,CASP7,NGFRAP1,ARRB1,GPER1,MAP3K5,XDH |
| 4.113e-03 | -5.49 | lipid modification | biological process | GO:0030258 | 150 | 35 | 16441 | 2455 |
MTM1,INPPL1,CPT2,INPP5D,TMEM55B,PRKAA1,PLPPR4,ECI1,B4GALNT1,INPP5E,PTEN,OCRL,IMPAD1,PIK3CA,ECI2,ABCD1,PIK3CD,ACOX2,PIKFYVE,ACAD8,SOAT1,PCCB,PIK3R1,PIP4K2C,SLC35C1,POR,PI4K2B,FA2H,ACADSB,ACAD10,PLPP3,PEX2,PIK3C2B,ADIPOR1,ACADM |
| 4.122e-03 | -5.49 | WEST_ADRENOCORTICAL_TUMOR_DN | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_DN | 533 | 100 | 17758 | 2588 |
PLA2G4A,SORBS1,DGKA,GMPR,NDRG2,EGR3,CCNL1,MICALL2,SEPT4,PHLDA1,IER3,ZYX,NOV,ZFP36,FOSB,AOX1,POLL,AKR1B1,CTTN,CTH,SEMA3B,SIRT1,SSH3,CD55,SEPT6,LYRM1,CASP9,PLEKHO1,PTGER4,TNS1,ASB13,NEIL1,SLC25A4,AXL,MYLK,MAP3K11,KLF5,KLF11,MAFF,ABCA1,CTDSP1,GSDMD,KLF2,ARHGEF3,IGFBP6,ALDH6A1,GCAT,SOX9,CYB561,NKRF,SORBS3,FBLN1,SIRPA,ICAM1,WWP2,IL17RB,GPC3,RPL39,CALD1,FUT8,COL6A1,ERBB3,MOXD1,MYLIP,ALDH3A2,RIMS2,EEF1D,FAH,DUSP1,DLGAP1,SPATA20,OPLAH,KLK5,FBLN5,ADCK3,NR4A1,OXR1,SRSF5,FOS,LEPR,RHOB,CRISPLD2,FAS,EPN3,RCBTB2,FAAH,CSF1,NAB2,ARAP1,NR4A3,ABCB1,NR4A2,PLD1,FHL1,ATP1B3,GEM,CD81,TOB1,IRF1,ABCG1 |
| 4.125e-03 | -5.49 | IWANAGA_CARCINOGENESIS_BY_KRAS_UP | MSigDB lists | IWANAGA_CARCINOGENESIS_BY_KRAS_UP | 159 | 36 | 17758 | 2588 |
MRC2,ST14,MCOLN3,ASB9,OSGIN2,CTSZ,POMGNT1,SDC1,NCS1,RAD23A,B4GALNT1,EPCAM,C16orf59,ELF5,DNM2,CKS1B,ACBD5,SOAT1,CD55,EPHA1,PPP1R14C,G2E3,GALNT3,PLEKHH2,ATP1A1,PAFAH1B3,GDE1,STK38,FAM3C,ATP6V1C1,WDR91,GLCCI1,HIPK3,SNX30,NIPA1,DENND5B |
| 4.128e-03 | -5.49 | BIOCARTA_PDGF_PATHWAY | MSigDB lists | BIOCARTA_PDGF_PATHWAY | 32 | 11 | 17758 | 2588 |
PDGFA,PLCG1,JAK1,STAT4,STAT6,PIK3R1,STAT1,PIK3CA,ELK1,FOS,RASA1 |
| 4.128e-03 | -5.49 | PROTEIN_AUTOPROCESSING | MSigDB lists | PROTEIN_AUTOPROCESSING | 32 | 11 | 17758 | 2588 |
MAP3K3,TNK1,INSR,IGF1R,AKT1,CDKL5,PAK2,KIAA1804,MAP3K11,MAP3K9,EIF2AK1 |
| 4.128e-03 | -5.49 | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | MSigDB lists | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | 32 | 11 | 17758 | 2588 |
MX1,AGRN,PLSCR1,IFITM3,STAT1,TAP1,TDRD7,IRF7,IFIT3,LGALS3BP,CKAP4 |
| 4.128e-03 | -5.49 | KASLER_HDAC7_TARGETS_2_DN | MSigDB lists | KASLER_HDAC7_TARGETS_2_DN | 32 | 11 | 17758 | 2588 |
KLF2,ADD3,CDH22,H1F0,TACC2,ZCCHC24,NFKBIA,MPP2,ACOX2,TNFRSF19,TSPAN17 |
| 4.128e-03 | -5.49 | chr6q14 | MSigDB lists | chr6q14 | 32 | 11 | 17758 | 2588 |
CD109,LCA5,FAM46A,IBTK,ANKRD6,TMEM30A,TBX18,HMGN3,SLC17A5,MAP3K7,COX7A2 |
| 4.137e-03 | -5.49 | positive regulation of cell-cell adhesion | biological process | GO:0022409 | 232 | 50 | 16441 | 2455 |
DHPS,IL15,ITGA6,HLA-E,TRAF2,FLOT1,GATA3,IL18,EGR3,CD274,TNFSF9,EFNB1,HLA-A,CD46,IL6ST,BMP7,PAK2,PIK3CA,IGFBP2,CITED2,MAP3K7,RAG1,WNT3A,FLOT2,SYK,RASGRP1,SOCS5,HES1,CD55,RHOA,RIPK2,AKT1,LGALS8,DMTN,PIK3R1,PRKCQ,YES1,CD83,BCL10,FYN,PLPP3,TBX18,NR4A3,NOD2,PIEZO1,ICOSLG,JAK3,RAP1GAP,L1CAM,FOXA1 |
| 4.138e-03 | -5.49 | nucleotide-activated protein kinase complex | cellular component | GO:0031588 | 12 | 6 | 17570 | 2579 |
PRKAA2,PRKAG2,PRKACA,NUAK1,PRKAA1,PRKAR1A |
| 4.157e-03 | -5.48 | cell activation | biological process | GO:0001775 | 664 | 124 | 16441 | 2455 |
PLA2G4A,MYL9,IL15,LFNG,CAST,NDRG1,TP53,DGKA,P2RX7,GATA3,IL18,ITPR2,SLC7A2,PDGFB,FLT3,TNFSF9,PDGFA,CALM2,CTNNB1,PLCG2,DLG1,SMO,BCL6,PIK3CA,PIK3CD,NFKB2,F2R,S100A13,RASGRP1,TUBA4A,LAMP2,SOD1,RIPK2,AKT1,LGALS8,PTGER4,CR2,PRKCQ,CD40,ITPR3,MYL12A,FZD7,LCP1,CMTM7,FYN,DDOST,ABHD12,HOXA9,STAT6,AXL,RPL22,HSPB1,F2RL1,ANXA3,RUNX2,CD63,HLA-E,DGKQ,HABP4,CALM3,AKAP17A,BTN3A1,TGFBR1,JAG2,NOTCH2,MERTK,IL18R1,ITGA2B,FZD6,ICAM1,HDAC9,RAC2,TIMP1,GATA2,KIF13B,CST3,CTPS1,MSH2,CD9,BAX,IL17RA,FNIP1,RAG1,WNT3A,DGKG,ULBP2,SYK,MSH6,P2RX4,RHOA,ADAM17,PLSCR1,MICB,CALM1,RC3H2,PIK3R1,RGCC,C1GALT1C1,ILK,BCAR1,GNA11,RHOB,DGKE,FAS,RASGRP2,TXK,DGKH,GNAS,CD8A,ONECUT1,TSC1,BANK1,SWAP70,SERPINA1,CSF1,DHRS2,ITPR1,NR4A3,ARRB1,FZD5,ICOSLG,TRPC3,JAK3,IRF1 |
| 4.180e-03 | -5.48 | Glycogen Metabolism | WikiPathways | WP500 | 37 | 13 | 4455 | 729 |
CALM2,PGM1,PPP2R5A,UGP2,CALM1,PPP2R4,GYS1,CALM3,PYGL,PHKA2,PPP2R5D,PHKG2,PPP2R3A |
| 4.189e-03 | -5.48 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-follicular_lymphoma | 221 | 47 | 17775 | 2585 |
ARHGEF3,FAM189A2,PARP14,ATP9A,CUL4B,TP53,IRX4,CNTNAP2,PM20D2,NOTCH2,FLT3,KIF26A,PRRG4,MYO5C,DIRAS3,RB1,UBE2Q2,P4HB,PTEN,BMP7,FAM102A,SLAIN2,PIM1,FAIM,SNX10,SYK,RIMS2,ZNF462,MX1,PIK3R1,UBAC1,KIF20B,TRIM35,IDH1,DOCK5,FAS,TBC1D17,ISM1,TMEM30A,STAT6,NFKBIA,ARRDC1,CLMN,XRCC3,ARHGAP4,TBC1D4,ABCA1 |
| 4.189e-03 | -5.48 | GTATTAT,MIR-369-3P | MSigDB lists | GTATTAT,MIR-369-3P | 198 | 43 | 17758 | 2588 |
CCNE2,LTBP1,SPRED1,PAX6,ZNF395,PPP1R12A,NUAK1,BACE1,ETV5,TRAPPC8,EPS8L2,FLRT3,MGAT4A,FNIP1,PDE4D,SLC39A10,PIKFYVE,WBP4,MOB4,SIRT1,SUN2,HES1,TAF5,CASK,KIF20A,MMD,AMFR,OXR1,RNF11,ZFAND5,NCOA3,FYN,RAB11FIP2,CDK19,MAP2,LIMK1,SPAG7,PCDH19,MAL2,CEP41,CBX4,ATMIN,PKIA |
| 4.189e-03 | -5.48 | V$HNF3ALPHA_Q6 | MSigDB lists | V$HNF3ALPHA_Q6 | 198 | 43 | 17758 | 2588 |
FARP1,REPS2,CHCHD7,IL18,GBX2,NEO1,SCML1,FOXP2,KCTD15,HSF2,ITGA3,CYR61,PRICKLE3,CALD1,VASN,BDH1,KLF3,SGK3,H2AFY,SGK1,TWIST1,PDE4D,SMARCA2,SSH3,SLC39A8,RGAG1,H2AFV,EBF2,GABARAPL1,PITX2,RBM47,PAFAH1B3,KLF12,COL13A1,NEIL3,NKD1,NR4A3,PPP1CB,TLE1,ADAMTS14,C1orf43,TOB1,RGMA |
| 4.191e-03 | -5.47 | MODULE_8 | MSigDB lists | MODULE_8 | 413 | 80 | 17758 | 2588 |
FOXM1,SUZ12,PTTG1,CCNB1,SDC1,ECI1,IER3,EPCAM,RCN1,ZYX,WEE1,PCNA,CCNA2,CYP1A1,ATP13A3,PSMC2,DNM2,GOT1,BTBD3,IL1RAP,CKS2,CPD,PLK1,SEC23A,SGCE,ACBD3,LYRM1,CDC20,COX11,HTATIP2,SLC11A2,AURKB,GTF2A2,ITPR3,ALCAM,CDK1,ZMPSTE24,MDK,AREG,IARS2,TLE1,MAD2L1BP,ANXA3,ITGA6,EPS8,PSMD7,GDF15,TXNDC9,SEPP1,CKAP5,PDIA4,TFAP4,TOP2A,PDCD10,CYR61,CTSC,GPC3,MSH2,SRP54,AHCY,MSH6,TMX1,PIGC,ZWINT,MMD,LPGAT1,GGH,MEST,PSMA4,CYB5A,STK17A,PROM1,SERPINA1,PLOD2,RND3,CCNB2,UBE2C,AHR,OCLN,CSRP2 |
| 4.193e-03 | -5.47 | ATPase activity, coupled to movement of substances | molecular function | GO:0043492 | 119 | 29 | 16491 | 2452 |
ATP9A,ATP8A1,RALBP1,ATP2C2,ABCG4,TAP1,ABCG2,ATP6V1E2,ATP1B1,ATP8B3,ATP10D,ABCD4,ATP13A2,ATP6V0B,TAPBP,ATP1A1,ATP7B,ATP13A3,PCYOX1,ABCA2,ABCB1,ATP8B1,ABCD1,ATP1B3,ATP6V1C1,ABCA1,ATP2B1,ABCC1,ABCG1 |
| 4.193e-03 | -5.47 | protein dephosphorylation | biological process | GO:0006470 | 188 | 42 | 16441 | 2455 |
MTM1,SSH1,DLGAP5,PPP1R12A,PPM1J,INPP5D,UBASH3B,CTDSPL,PHLPP1,SBF1,DUSP5,PPP2R3A,EPM2A,PTEN,PALD1,PPP4R1,DLG1,DUSP10,PPP1CA,PTPRE,CTDSP2,CAMK2G,DUSP1,SSH3,PTPN18,PTPRU,PTPN9,PTPRH,DUSP23,DUSP4,CDC25C,SGPP1,PTPRF,ATP1A1,PTPRJ,PLPP3,PHLPP2,PPM1H,PPP1CB,PPP2R5D,CPPED1,CTDSP1 |
| 4.205e-03 | -5.47 | kidney epithelium development | biological process | GO:0072073 | 129 | 31 | 16441 | 2455 |
HES1,LGR4,FMN1,IQGAP1,RET,EPHA4,SOX9,DCHS1,SDC4,GATA3,ILK,SDC1,IRX3,CTNNBIP1,EPCAM,BMP2,PROM1,FAT4,CTNNB1,NPNT,FGFR2,GPC3,BMP7,DLG1,SMO,PKD2,TACSTD2,GDF11,OSR1,SOX8,ADAMTS16 |
| 4.205e-03 | -5.47 | DARWICHE_SKIN_TUMOR_PROMOTER_UP | MSigDB lists | DARWICHE_SKIN_TUMOR_PROMOTER_UP | 132 | 31 | 17758 | 2588 |
SUN1,SOD1,IFITM3,TRAF2,NUF2,MRPS18A,SPNS3,EXT2,ART5,ICAM1,RAB2B,CAPN2,TP73,MAN2A2,CXCL16,SPP1,IDE,IRAK1,PFKL,AXL,ARAP1,ACTA2,NPTXR,ARHGAP4,CMPK2,CITED2,LRIF1,UBE2C,CHPT1,CCDC38,PAQR7 |
| 4.207e-03 | -5.47 | VANTVEER_BREAST_CANCER_BRCA1_DN | MSigDB lists | VANTVEER_BREAST_CANCER_BRCA1_DN | 41 | 13 | 17758 | 2588 |
KLHL2,UBE2Q2,MID1IP1,CA2,ZNF395,NQO1,FAM110C,SH3BP4,APPL2,PRKG1,NEURL1B,ECI1,SLC9A2 |
| 4.207e-03 | -5.47 | NAKAYAMA_FRA2_TARGETS | MSigDB lists | NAKAYAMA_FRA2_TARGETS | 41 | 13 | 17758 | 2588 |
LGR4,NR1D2,CKAP2,BCL6,SGK1,DUSP10,CTTN,DUSP4,LGMN,F2R,ZFAND5,SLC20A1,STK17B |
| 4.207e-03 | -5.47 | GROSS_HYPOXIA_VIA_ELK3_ONLY_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_ONLY_DN | 41 | 13 | 17758 | 2588 |
CDKN2C,TRIM8,CENPA,DOK4,S100A4,AOX1,CBX6,KIF23,ARRB1,RACGAP1,NDE1,MINPP1,ABCG1 |
| 4.207e-03 | -5.47 | ZHAN_MULTIPLE_MYELOMA_LB_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_LB_UP | 41 | 13 | 17758 | 2588 |
PCGF5,KIAA0895,CGREF1,BIK,PLEKHA7,PLS1,ARNT2,PLXNA1,CTTN,RELL1,MAST4,RASGRP1,CYBRD1 |
| 4.207e-03 | -5.47 | MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP | MSigDB lists | MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP | 41 | 13 | 17758 | 2588 |
BMP2,NFE2L3,RB1,CTSB,SLC44A1,PRKCI,DDR1,CDK1,NR2C1,PICK1,CYB5A,NFIX,FAS |
| 4.214e-03 | -5.47 | AhR pathway | WikiPathways | WP2100 | 29 | 11 | 4455 | 729 |
AHRR,HES1,CYP1A1,NQO1,BAX,CDKN1B,AHR,AIP,ARNT,EGFR,CYP1B1 |
| 4.215e-03 | -5.47 | nuclear envelope organization | biological process | GO:0006998 | 73 | 20 | 16441 | 2455 |
PLK1,SUN1,SUN2,TMEM43,SYNE2,CCNB1,CDK1,LMNA,ZMPSTE24,LEMD2,NUP210,SUN3,GPER1,NUP37,CCNB2,REEP4,NUP58,NUP85,CNEP1R1,DMPK |
| 4.215e-03 | -5.47 | response to type I interferon | biological process | GO:0034340 | 73 | 20 | 16441 | 2455 |
MX1,IFITM3,HLA-E,USP18,HLA-F,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,SP100,STAT1,IRF2,IRF7,RNASEL,HLA-C,OAS3,IFIT1,IFI6,IRF1 |
| 4.216e-03 | -5.47 | AGGAAGC,MIR-516-3P | MSigDB lists | AGGAAGC,MIR-516-3P | 116 | 28 | 17758 | 2588 |
POU6F1,SPRED1,KLK10,ERMP1,STAT4,DCAF7,BNIP3L,COL18A1,RUNX3,PPP1R14C,HERC6,CBL,SPTB,DUSP5,CHST2,ZNF385B,WEE1,VASP,KHNYN,CSNK1G1,VASN,SERPINB5,H2AFY,PIK3C2B,IFIT1,NCAM1,ATP6V1C1,RIMS2 |
| 4.221e-03 | -5.47 | REGULATION_OF_DEVELOPMENTAL_PROCESS | MSigDB lists | REGULATION_OF_DEVELOPMENTAL_PROCESS | 437 | 84 | 17758 | 2588 |
CASP3,ACVR1,XIAP,TP53,CUL1,BCL2L1,AIFM2,BARD1,IER3,TP73,CDKN2C,DAPK2,SIVA1,BCL6,CDKN1B,TNFRSF18,F2R,CDKN2D,MX1,BAG4,SOD1,ACVR1C,CASP9,BNIP3L,HTATIP2,GLO1,STK17B,CDK1,CASP4,VCP,SOCS3,MADD,STAT1,HDAC1,HSPB1,AIFM3,CBX4,FGD1,HSP90B1,ARAP3,TAOK2,DAP,CTSB,BIK,SERPINB9,NOTCH2,GSTP1,ADAMTSL4,ETS1,HDAC9,CALR,TOP2A,CARD8,ADORA1,IGF1R,PTEN,BAX,DAPK1,CD70,PIM1,ERCC2,NPTN,TMX1,SOCS5,GCLC,TCFL5,RUNX3,NPHP3,BCAR1,RHOB,CDK5R1,RASA1,STK17A,FAS,BCL10,BTG1,SEMA4D,HTT,SCG2,ARAP1,FGD6,MAP3K5,IFI6,HIPK3 |
| 4.224e-03 | -5.47 | ossification | biological process | GO:0001503 | 249 | 53 | 16441 | 2455 |
CTHRC1,INPPL1,MRC2,RUNX2,SORT1,HSPG2,LGR4,THRA,SOX9,PHOSPHO1,EXT2,BMP2,SPP1,CTGF,CYR61,BMP7,GPC3,IMPAD1,PSMC2,RRBP1,COL6A1,RDH14,SMO,SUCO,TWIST1,OSTF1,ERCC2,MINPP1,WNT3A,RHOA,AKT1,FIGNL1,DCHS1,ANO6,FHL2,RUNX3,TP53INP2,EGFR,GPLD1,GNAS,PTGS2,FAT4,FGFR2,TWSG1,SEMA4D,COL13A1,NAB2,WWTR1,FGF18,BMP1,CSGALNACT1,SOX8,SHOX2 |
| 4.226e-03 | -5.47 | TGACATY_UNKNOWN | MSigDB lists | TGACATY_UNKNOWN | 631 | 116 | 17758 | 2588 |
LTBP1,SLC2A4,SORBS1,ST13,WDTC1,TEX2,DDR1,PCBP1,SLC25A35,C1orf116,CYP26A1,PAK6,PDGFA,SS18,SESN3,ST5,TACC2,MITF,DUSP10,PDE4D,OSBPL7,MYT1,TRIM8,ASXL1,ACVR1C,SYNE2,RNF11,SAT1,PRKAR2B,ATP1B1,SNX12,ABR,EBF2,IRX3,TRIM9,FYN,WIPI1,MAP2,KCNK1,MYLK,MADD,INPP4B,CTNND1,RCAN2,SYT13,LEMD1,C1orf43,ARF6,TTC39C,ARHGAP4,STARD13,ST3GAL1,LIFR,ARHGEF3,FRMD4A,IGFBP6,CHCHD7,DCAF7,PDIA3,SORBS3,COL4A5,TGFBR1,DOCK11,APBA1,SBF1,TNFRSF19,FGF19,SLC9A2,NRP2,SH2D4A,FOXP2,VASP,LRRN2,ANKS1B,CTSC,SLC16A6,CALD1,TMEM62,FLRT3,KIF13B,KLF9,CACNA1D,ERBB3,STT3B,IQGAP3,CITED2,ZRANB1,MYLIP,IGSF3,DNAI1,MOB4,ARAP2,NR3C1,PIK3R1,LITAF,KBTBD8,RUNX3,AKAP3,TP53INP2,FOS,EGFR,BSDC1,MAP1B,XKRX,ARHGAP24,CD8A,CCDC6,PLOD2,FGFR2,PELI2,SFMBT1,MDH1,GEM,HOOK1,JARID2,EHD1 |
| 4.234e-03 | -5.46 | bicellular tight junction | cellular component | GO:0005923 | 110 | 27 | 17570 | 2579 |
DDX58,AMOTL2,FRMD4A,CRB3,BVES,PARD3B,RAPGEF2,TGFBR1,F11R,MPP5,MICALL2,EPCAM,CCND1,VASP,TJP3,CTNNB1,TBCD,RAP2C,PRKCI,DLG1,CLDN4,POF1B,EPB41L4B,DLG3,FZD5,SHROOM2,OCLN |
| 4.249e-03 | -5.46 | ESTABLISHMENT_OF_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_LOCALIZATION | 860 | 153 | 17758 | 2588 |
SLC25A13,ARFGEF1,BAIAP3,SYTL4,ERP29,CACNB4,SLC20A1,BARD1,PICK1,ABCD4,ZFYVE16,NAPG,AP1M2,TM9SF2,STIM1,LMAN2L,SLC44A1,SLC46A1,STEAP2,KCNS3,ABCA2,TRPC1,TINAGL1,TRAM1,UXT,ERP44,SLC17A5,ICMT,SLC25A5,TCN2,VCP,OPTN,EDNRA,KCNMB4,SLC25A4,KCNK1,ATP7B,NOD2,KPNA2,ARF6,SLC31A2,SCN5A,LASP1,ARAP3,NFKBIE,PEX6,GGA1,FXYD3,ABCG2,SLC1A3,APBA1,PGAP1,ATG4A,CALR,DOPEY2,GATA2,SLC16A6,KCNN4,KIF13B,PRKCI,SORL1,CACNA1D,KDELR1,ABCC1,MDFI,NAGPA,KCNJ12,KIF20A,STRADB,NPC2,RHOB,EGFR,TSC1,CDCA5,SH3BP4,CTSA,LTBP2,PLIN3,SHROOM2,TRPC3,NRBP1,SLC2A4,SORBS1,KCNAB3,SLC2A8,RALBP1,TP53,SLC7A2,BCL2L1,APPBP2,SYTL2,ZFYVE9,ATP6V0B,SCNN1A,CDH1,REEP1,BCL6,SCN2A,LMAN1,ARL4D,F2R,ATG4D,SEC23A,AKT1,COG2,VPS4B,KIF1C,HTATIP2,SLC11A2,NUSAP1,CBL,CORO1C,ABCA1,TRAPPC10,PDIA3,KCNC4,NFAT5,AIP,M6PR,CKAP5,PDIA4,KIF5B,CARD8,ADORA1,PPP1R10,KCNK5,SLC35B4,BAX,SLC44A2,SGK1,CPLX1,TTPA,SLC16A5,RPGR,SLC35A1,TMX1,SUN2,ZWINT,PPARA,VAMP3,AKAP3,MAPK8IP1,KLHL2,LDLRAP1,CTNS,SCG2,ABCB1,ARFGAP3,PKD2,CENPE,ATP6V1C1,ARSB,ABCG1 |
| 4.254e-03 | -5.46 | INTRACELLULAR_TRANSPORT | MSigDB lists | INTRACELLULAR_TRANSPORT | 278 | 57 | 17758 | 2588 |
NFKBIE,PEX6,GGA1,TP53,PDIA3,BCL2L1,APBA1,BARD1,ERP29,ZFYVE9,APPBP2,M6PR,ATG4A,KIF5B,ZFYVE16,CALR,DOPEY2,NAPG,AP1M2,CDH1,PPP1R10,LMAN2L,KIF13B,STEAP2,ABCA2,BCL6,TINAGL1,LMAN1,F2R,TRAM1,RPGR,TMX1,KDELR1,MDFI,ATG4D,NAGPA,AKT1,COG2,UXT,VPS4B,HTATIP2,STRADB,KIF1C,NPC2,ICMT,VCP,RHOB,OPTN,KLHL2,TSC1,KPNA2,CTSA,LTBP2,ARSB,NRBP1,ABCA1,ABCG1 |
| 4.255e-03 | -5.46 | positive regulation of macromolecule biosynthetic process | biological process | GO:0010557 | 1634 | 281 | 16441 | 2455 |
ACVR1,TRIM24,LGR4,TRIM5,DNAJC3,HEXB,RET,GATA3,MORF4L2,CAMK1D,TP73,NPM2,HELZ2,CTGF,IL31RA,FOSB,DNM2,IRF2,NEK4,SMARCA2,TNIP1,TFAP2C,AURKB,LDB2,SAV1,ARF4,AHRR,AREG,TBX1,NOD2,HDAC1,RNASEL,HSPB1,TRAF5,F2RL1,E2F8,HOXC13,DDX58,KLF2,CDKN1C,ITGA6,SOX9,PSIP1,LMNA,MECOM,ELF3,TFAP4,CALR,CYR61,NEK2,MYDGF,MAPK7,NUP85,SALL4,STAT4,PYM1,FHL2,MYBL2,ELK1,ILK,TP53INP2,KDM3A,NFIB,NCOA3,SERTAD2,ETS2,SETD3,PIAS2,NR4A2,RPS6KA3,TMEM173,IRF1,ARMCX3,GRHL2,THRA,RPS6KA1,CCNA2,CDH1,SP100,DAB2IP,ETV4,MED30,PSRC1,RIPK2,FZD4,FOXJ2,PRKCQ,PXYLP1,PYGO1,GTF2A2,EBF2,FZD7,NFIX,IRS2,WWTR1,STAT1,KLF5,NRG1,ARNT,ATMIN,NKX3-1,CKAP2,TRAF2,PBX3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,E2F7,IRAK1,PTEN,MCF2L,CST3,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,PDGFC,CASK,PLSCR1,BCL9,TEF,PIK3R1,EIF5A2,GRIN1,YES1,FOS,ABLIM2,TXK,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,NR1D2,ACVRL1,NR4A3,GPER1,HMGA1,FZD5,OSR1,CD81,USF2,SHOX2,FOXA1,USP16,RGMA,CCNC,EPAS1,AGRN,ARFGEF1,HDAC6,PDGFB,TFAP2E,EPCAM,HSF2,PCNA,CTNNB1,GRHL1,NPNT,ELF5,PASK,MITF,PSMC2,ASH2L,ARNT2,MYBL1,ZNF462,THRB,PCGF5,TRIM8,CITED4,ASXL1,NFE2L1,EAF2,SEC14L2,MDK,KLF12,MAFF,PSMC1,NR2C2,RUNX2,PPP1R12A,ETV5,BMP2,RB1,IGF1R,GATA2,SUCO,PRKCI,EBF4,MDFIC,WNT3A,ELK3,RGMB,EGFR,MAPKAPK2,ONECUT1,INSR,PLPP3,NFKBIA,NLRC5,RARG,RAD21,KLF7,PAX6,SORBS1,UPF3B,IL15,FOXM1,TP53,ERBB2,CCNL1,OSR2,LPIN3,PDGFA,SS18,LMO4,SMO,TWIST1,ZBTB49,NOTCH3,NFKB2,F2R,DVL2,UPF3A,CTH,CHP1,SOAT1,SIRT1,AKT1,TCEB2,SERTAD3,CD40,JADE1,HSF4,RBL1,STAT6,IRF7,AKNA,GLIS3,ANXA3,PINK1,TAB3,ARHGEF11,HMGN3,TGFBR1,PARM1,GBX2,TOP2A,IRF2BPL,BMP7,TOX2,TFAP2A,GTF2F2,BRD7,TRIM21,SYK,NFE2L3,HES1,RHOA,DCAF6,HMGN5,WNT10B,NR3C1,NR4A1,RGCC,PPARA,MAML2,RUNX3,MPV17L2,BCL10,E2F1,ARRB1,PKD2,ZMIZ1,SOX8,AHR |
| 4.265e-03 | -5.46 | ERBB3 (erb-b2 receptor tyrosine kinase 3) | protein interactions | 2065 | 83 | 23 | 16036 | 2547 |
AKT1,CD82,PIK3R1,ERBB2,NRG2,HDAC6,HLA-A,EGFR,RASA1,TXK,BCAR3,TNS4,TNS3,PLCG1,SHC3,IL6ST,LRIG1,NRG1,ERBB3,JAK3,SYK,ODF2L,TUBA4A |
| 4.267e-03 | -5.46 | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_DN | 187 | 41 | 17758 | 2588 |
BIN1,CCNI,TRIP10,PPM1J,TMEM55B,CCNO,GPR180,TAF6L,CDIPT,CENPN,UBE2Q2,RNF220,KIAA1107,PAPSS1,ESPN,RPN2,AHCY,CRTAP,KDELR1,CYP1B1,GCNT1,SUSD3,SYPL1,ARHGDIB,FXR2,SNAPC2,FNDC3A,PPP1R14C,FAM109A,FANCE,GNA11,C18orf8,SOCS3,XKRX,AHRR,ACVRL1,ITGA7,GLA,REEP4,MIIP,DEF6 |
| 4.267e-03 | -5.46 | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDM_DN | 187 | 41 | 17758 | 2588 |
CCNI,SORT1,RASA2,ATP2C2,ARFGEF1,TESK2,NDRG2,MESDC2,PLS3,ATP6V0B,TM9SF2,PFKL,ZDHHC12,FICD,FJX1,RRBP1,DLG1,ADAM15,SRP54,IL17RA,TMBIM6,ESPN,F2R,HSPA2,IL1RAP,EEF1D,TMX1,PARP9,FOXJ2,SYNE2,SLC35C1,ESYT1,YES1,LDB2,TP53INP2,ZMPSTE24,SFXN1,WIPI1,KBTBD2,PPP2R4,RPS6KA3 |
| 4.267e-03 | -5.46 | GSE14769_40MIN_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_40MIN_VS_360MIN_LPS_BMDM_UP | 187 | 41 | 17758 | 2588 |
NUDT6,GOLIM4,FAM160B1,HABP4,PDCL,DENND2D,LBR,SAC3D1,UHRF1BP1L,MESDC2,PQLC2,ENTPD4,PRKCI,AHCY,FAM84B,RCAN3,BTBD3,S100A6,CRTAP,FARP2,TAF5,BAG4,MRPS33,MBP,TEP1,ARHGDIB,MRPS35,MCFD2,CTNS,WDR11,RAB11FIP2,NEIL3,OTUD6B,E2F1,NR4A3,DHTKD1,CTSA,CPEB2,PDPR,PRKAR1A,ABCG1 |
| 4.274e-03 | -5.46 | skin epidermis development | biological process | GO:0098773 | 78 | 21 | 16441 | 2455 |
LGR4,LRP4,SOX9,TFAP2C,SAV1,LDB2,TNFRSF19,FZD6,EGFR,ZDHHC21,GNAS,PDGFA,CD109,CTNNB1,FGFR2,CTSV,DBI,SMO,HDAC1,ERCC2,HOXC13 |
| 4.274e-03 | -5.46 | toll-like receptor 2 signaling pathway | biological process | GO:0034134 | 78 | 21 | 16441 | 2455 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PIK3AP1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 4.276e-03 | -5.45 | EPHA2 forward signaling | Pathway Interaction DB | epha2_fwdpathway | 17 | 9 | 2227 | 480 |
RHOA,INPPL1,PIK3R1,PIK3CA,EFNA1,CBL,BCAR1,TIAM1,ARHGAP35 |
| 4.284e-03 | -5.45 | HILLION_HMGA1B_TARGETS | MSigDB lists | HILLION_HMGA1B_TARGETS | 90 | 23 | 17758 | 2588 |
SOD1,PCOLCE,TIMP2,PSMB4,PLAUR,CRIP2,ERBB2,SLC25A5,FOS,VCP,GRM5,COX7A2,PDGFA,RPL12,PCNA,ATP5H,LIMK1,NFKBIA,AK3,UNC5B,ARF6,ALDH3A2,GPX4 |
| 4.299e-03 | -5.45 | ensheathment of neurons | biological process | GO:0007272 | 88 | 23 | 16441 | 2455 |
SOD1,MBP,UGT8,AKT1,NDRG1,HEXB,ERBB2,KLK6,MPP5,ILK,DAG1,PRX,CNTNAP1,TSC1,FA2H,PTEN,NAB2,CD9,NRG1,ERCC2,SCN2A,PIKFYVE,MYO5A |
| 4.299e-03 | -5.45 | axon ensheathment | biological process | GO:0008366 | 88 | 23 | 16441 | 2455 |
SOD1,MBP,UGT8,AKT1,NDRG1,HEXB,ERBB2,KLK6,MPP5,ILK,DAG1,PRX,CNTNAP1,TSC1,FA2H,PTEN,NAB2,CD9,NRG1,ERCC2,SCN2A,PIKFYVE,MYO5A |
| 4.299e-03 | -5.45 | multicellular organismal macromolecule metabolic process | biological process | GO:0044259 | 88 | 23 | 16441 | 2455 |
COL9A3,ADAMTS2,MRC2,ADAM17,COL6A2,CTSB,P3H2,FURIN,P2RX7,COL18A1,KLK6,COL4A5,COL7A1,COL12A1,CTSL,MMP15,TRAM2,COL13A1,COL6A1,ADAM15,ADAMTS14,CTSD,COL16A1 |
| 4.301e-03 | -5.45 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0031145 | 83 | 22 | 16441 | 2455 |
PLK1,PSMB4,CIT,PSME2,PTTG1,CDC20,PSMD7,CUL1,PSMD10,PSME1,AURKB,CCNB1,PSMA4,CDK1,PSMD1,PSMD3,PSMC2,NEK2,AURKA,UBE2C,PSMC1,PSMA5 |
| 4.301e-03 | -5.45 | regulation of sodium ion transport | biological process | GO:0002028 | 83 | 22 | 16441 | 2455 |
PRSS8,P2RX4,SCN5A,SERPINE2,AKT1,FXYD3,UTRN,PKP2,P2RX7,NKAIN1,ATP1B1,SNTA1,NKAIN3,ATP1A1,SGK3,DNM2,DLG1,SGK1,FXYD5,ATP1B3,CHP1,DMPK |
| 4.319e-03 | -5.44 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 60 | 17 | 17758 | 2588 |
LTBP1,PLSCR4,GOLIM4,CDYL,EPHA4,CALCRL,PRKAR2B,STK17B,SCML1,PITX2,GNAS,ZNF75D,TWSG1,LMO4,SGK1,MDFIC,LIFR |
| 4.329e-03 | -5.44 | Endometrial cancer | KEGG pathways | hsa05213 | 52 | 16 | 6908 | 1076 |
AKT1,PIK3R1,CASP9,TP53,ERBB2,TCF7,ILK,ELK1,APC2,EGFR,CCND1,CDH1,CTNNB1,PTEN,PIK3CA,PIK3CD |
| 4.329e-03 | -5.44 | Endometrial cancer | KEGG pathways | ko05213 | 52 | 16 | 6908 | 1076 |
AKT1,PIK3R1,CASP9,TP53,ERBB2,TCF7,ILK,ELK1,APC2,EGFR,CCND1,CDH1,CTNNB1,PTEN,PIK3CA,PIK3CD |
| 4.332e-03 | -5.44 | PML (promyelocytic leukemia) | protein interactions | 5371 | 193 | 45 | 16036 | 2547 |
RUNX2,TRIM24,THRA,SUZ12,HDAC11,TP53,CUL1,TGFBR1,HDAC6,MXD1,ZFYVE9,LMNA,PER2,IER3,TP73,SAP130,RB1,SP100,CTNNB1,GATA2,BCL6,MAPK11,MAPK7,NR2C1,NCOA2,SIRT1,TGIF1,PLSCR1,NR3C1,NR4A1,SYNE2,RUNX3,PKM,FOS,CDK1,EGFR,FAS,PLCG1,JAK1,HTT,TRIM69,PIAS2,AURKA,HDAC1,ARNT |
| 4.335e-03 | -5.44 | antigen receptor-mediated signaling pathway | biological process | GO:0050851 | 172 | 39 | 16441 | 2455 |
THEMIS2,INPP5D,PSME2,PSMD7,BTN3A1,GATA3,CUL1,PSMD10,PSME1,TEC,CACNB4,VASP,PSMD1,PTEN,PSMC2,PAK2,PLCG2,BAX,PIK3CA,PIK3CD,PDE4D,MAP3K7,SYK,PSMA5,PSMB4,RIPK2,PIK3R1,PRKCQ,BCAR1,PSMA4,TXK,BCL10,PLCG1,PTPRJ,FYN,PSMD3,NFKBIA,UBE2D2,PSMC1 |
| 4.336e-03 | -5.44 | V$NFAT_Q6 | MSigDB lists | V$NFAT_Q6 | 238 | 50 | 17758 | 2588 |
KIF3C,LASP1,ACVR1,CPEB4,HSPG2,TAB3,ETV5,NDRG2,RNF182,NKRF,PLAC1,NOTUM,CD274,RAB6A,BAHD1,PDGFB,TSEN34,PRRG4,PER2,FOXP2,NAPG,INPP5E,ADRBK1,RNF128,TACC2,PRICKLE4,FJX1,MITF,ELF5,CAPG,PIK3CD,PDE4D,FRS3,ELK3,RHOA,CAPN6,PITX2,TRIM47,TMEM54,CCDC6,PLOD2,NR4A3,CTNND1,ARF6,SGOL1,SHOX2,NR3C2,COL16A1,JARID2,IRF1 |
| 4.351e-03 | -5.44 | PUJANA_XPRSS_INT_NETWORK | MSigDB lists | PUJANA_XPRSS_INT_NETWORK | 165 | 37 | 17758 | 2588 |
RECQL,SPC25,FOXM1,SUZ12,NDC80,LBR,PSIP1,FANCI,TOP2A,CDKN2C,RB1,PCNA,CCNA2,CNTRL,PLK4,MSH2,USP1,KNTC1,MPHOSPH9,SMC4,HMMR,CENPA,ZWINT,CDC20,MYBL2,WHSC1,KIF20B,AURKB,CCNF,H2AFV,CDK1,DCP2,ACYP1,AURKA,UBE2C,ESPL1,RAD21 |
| 4.359e-03 | -5.44 | endothelial cell migration | biological process | GO:0043542 | 54 | 16 | 16441 | 2455 |
NR4A1,TGFBR1,LOXL2,EGR3,EMP2,S100A2,CORO1B,GPLD1,NOV,PTEN,SCG2,PIK3CA,STAT1,EPHB4,PLXND1,CYP1B1 |
| 4.361e-03 | -5.43 | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | MSigDB lists | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | 261 | 54 | 17758 | 2588 |
DDX58,INPPL1,TAB3,HLA-F,CUL1,HERC5,IL18,HLA-A,ICAM1,NUP210,IRAK1,SP100,IL6ST,PIK3CA,IRF2,IFIT1,PIK3CD,HLA-C,OAS3,MAP3K7,NCAM1,NFKB2,SYK,NUP85,IL1RAP,MAP3K3,MX1,ADAM17,RIPK2,IFITM3,USP18,PIK3R1,YES1,PELI3,IFIT3,CBL,CDK1,SOCS3,IRS2,IL1R1,HLA-B,PLCG1,FYN,JAK1,PELI2,STAT1,NOD2,IRF7,KPNA2,RNASEL,NUP37,JAK3,IFI6,IRF1 |
| 4.363e-03 | -5.43 | LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | MSigDB lists | LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | 85 | 22 | 17758 | 2588 |
TIMP2,MBP,LGALS3,EPHA4,SAT1,TAP1,ARHGDIB,PLA2G16,IFIT3,FBLN1,PLEKHB1,HDAC9,CDKN2C,PITX2,NOV,SPP1,PLOD2,STAT1,RNASEL,LTBP2,SERPINB1,IRF1 |
| 4.363e-03 | -5.43 | IVANOVSKA_MIR106B_TARGETS | MSigDB lists | IVANOVSKA_MIR106B_TARGETS | 85 | 22 | 17758 | 2588 |
ELK4,PLSCR4,EIF5A2,FAM134A,PRRG4,FZD6,ZFYVE9,CCND1,BTG3,JAK1,ZNF367,LIMK1,ENPP5,NETO2,CLIP4,PKD2,ZBTB6,NCEH1,RASGEF1A,PKIA,CYBRD1,RGMA |
| 4.392e-03 | -5.43 | kinesin binding | molecular function | GO:0019894 | 36 | 12 | 16491 | 2452 |
AP1AR,PIFO,KLC2,SYBU,FAM83D,PRC1,CLSTN1,KLC3,SPTBN5,ARPC2,KTN1,MAPK8IP1 |
| 4.393e-03 | -5.43 | central nervous system development | biological process | GO:0007417 | 859 | 156 | 16441 | 2455 |
CASP3,EMX1,UGT8,HSPG2,AK7,EPHA4,SUDS3,NDRG2,SEPT4,DNER,TP73,CALM2,CDKN2C,CTNNB1,SHC3,DPYSL2,ALDH1A3,DUSP10,ARNT2,ZBTB18,BTBD3,SPEF2,CELSR2,TFAP2C,KLK6,ARF4,ABR,MDK,MAP2,TBX1,SERPINI1,NRGN,SCN5A,SERPINE2,SOX9,RAB23,CALM3,CNTNAP2,NCKAP1,HPCAL4,PGAP1,MECOM,BMP2,IGF1R,GATA2,PRKG1,WNT3A,ALDH3A2,CALM1,SHARPIN,TCF7,SCRIB,NFIB,EGFR,CDK5R1,FAS,TSC1,FA2H,HTT,PLPP3,PHLPP2,PCDH19,NR4A2,GDF11,NDE1,DRP2,SHROOM2,SEMA3A,RPS6KA3,DRD1,PAX6,NF2,GRHL2,CAST,THRA,HDAC11,TP53,ERBB2,PHLDA1,STIL,SDF4,TTC21B,APLP2,CDH1,TACC2,LMO4,KIF14,LHX6,SRR,SMO,DIXDC1,DAB2IP,NOTCH3,MBP,TIMP2,FZD4,NFIX,ARHGAP35,IRS2,FYN,PTPRJ,ALDH5A1,PAFAH1B3,AXL,NRG1,ANXA3,WASF3,CDH22,JRKL,ADGRG1,HAPLN3,PBX3,NES,SEPP1,ETS1,GSTP1,HOXB2,FZD6,GBX2,FOXP2,OXCT1,PTEN,KNDC1,CST3,CD9,BAX,TFAP2A,WWP1,ERCC2,POU6F1,PDGFC,HES1,RHOA,ARHGEF28,TACC1,ASPM,RAPGEF2,GRIN1,AK4,BBS2,PITX2,CDK5RAP1,TIMP3,CTNS,FAT4,TWSG1,FGFR2,DBI,RYK,NR4A3,E2F1,PKD2,WDR62,SOX8,ARSB,JARID2 |
| 4.408e-03 | -5.42 | MORF_BUB1B | MSigDB lists | MORF_BUB1B | 65 | 18 | 17758 | 2588 |
HMMR,PLK1,ZWINT,CENPA,NDC80,WHSC1,KIF20B,GTF2A2,CDK1,CDKN2C,TOP2A,CCNA2,OXCT1,KIF14,PLK4,BUB1,ESPL1,NAGA |
| 4.408e-03 | -5.42 | PID_BCR_5PATHWAY | MSigDB lists | PID_BCR_5PATHWAY | 65 | 18 | 17758 | 2588 |
IBTK,AKT1,INPP5D,PIK3R1,ELK1,FOS,ETS1,RASA1,BCL10,PTEN,PIK3AP1,CD22,NFKBIA,PLCG2,PIK3CA,MAP3K7,SYK,CAMK2G |
| 4.418e-03 | -5.42 | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | MSigDB lists | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | 390 | 76 | 17758 | 2588 |
EXPH5,NQO1,CRYM,ATP2C2,ABCG4,PKP2,PLXNA1,SNN,DDR1,PDGFB,PHLDA1,PHF1,ARHGEF16,PICK1,RGS12,SCNN1A,RABEP2,MITF,PIK3CD,EPHB4,ARL4D,MBP,LGALS8,ARFRP1,SNAPC2,ALDH3B1,ACAD10,TRIOBP,RAB11FIP1,NRG1,KLF2,PINK1,MRC2,CDKN1C,FAM189A2,NUAK1,FXYD3,BIK,CALB2,HPCAL4,LMNA,IL22RA1,NRP2,ITGA2B,TMEM63A,SNTA1,VASP,NOXA1,MLPH,LRRN2,CD22,RRBP1,ACTA2,MAST4,ETV7,DUSP1,FADS2,PCDH1,NR4A1,PLAUR,FURIN,PYGL,FBXO9,GNA11,PRX,EGFR,NMT2,RHPN1,MOSPD3,FA2H,PVRL2,MPP2,ARRB1,LTBP2,PTGES,FOXA1 |
| 4.421e-03 | -5.42 | cyclin-dependent protein serine/threonine kinase inhibitor activity | molecular function | GO:0004861 | 12 | 6 | 16491 | 2452 |
CDKN1B,CDKN2C,CASP3,HEXIM2,CDKN1C,CDKN2D |
| 4.425e-03 | -5.42 | monocarboxylic acid metabolic process | biological process | GO:0032787 | 510 | 98 | 16441 | 2455 |
PLA2G4A,ACACB,UGT8,UGP2,CPT2,MCCC1,MGST2,LPIN3,ECI1,CYP39A1,CYP26A1,PER2,CYP1A1,P4HB,CYP2S1,ALDH1A3,FABP6,SRR,ACSL4,ACOX2,TECR,EGLN3,GPX4,CYP1B1,PFKFB2,PANK1,PRKAR2B,GLO1,IDH1,PNKD,CYP4F3,PDHX,POR,PTGS2,ALDH5A1,ACAD10,P4HA2,PEX2,DHTKD1,SLC27A1,ADIPOR1,CYP2U1,LTA4H,SLC27A3,PPP2R5D,PDPR,DLAT,PRKAA2,FAM213B,ENO2,CYP2J2,SCD5,ELOVL7,HAL,PRKAA1,SLC1A3,CRABP2,DSE,SGPL1,SLC27A6,PFKL,ATP8B1,ECI2,ABCD1,ACAD8,SYK,NCOA2,CRTAP,MCCC2,MYO5A,ABCC1,CYP26B1,FADS2,PCCB,PGM1,PRODH,SHMT1,ERO1A,ELOVL3,OGDHL,PPARA,PDK3,PKM,RNPEP,AMDHD1,PRDX4,MAPKAPK2,PRKAG2,FA2H,ACADSB,FAAH,HTT,PLA2G15,NR4A3,ACADM,PTGES,ACOT7,EGLN1 |
| 4.425e-03 | -5.42 | XIAP (X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase) | protein interactions | 331 | 132 | 33 | 16036 | 2547 |
CASP3,TCF25,TRAF2,INPP5D,PTTG1,XIAP,TGFBR1,GMCL1,PRSS22,SEPT4,SSX2IP,PTEN,SIVA1,BAX,CKS1B,AHCY,FAIM,SCARA3,MAP3K7,MAP3K3,TRIM8,RIPK2,AKT1,CASP9,STRADB,CASP4,BCL10,CASP7,ACVRL1,PRDX3,UBE2D2,NOD2,E2F1 |
| 4.435e-03 | -5.42 | MODULE_13 | MSigDB lists | MODULE_13 | 504 | 95 | 17758 | 2588 |
SPC25,EPAS1,ST14,CD82,INPP5D,DGKA,P2RX7,TGOLN2,ITPR2,VASH1,BAHD1,SLC9A3R2,CARD10,EPM2A,PICK1,DAPK2,CDKN2C,ST5,SRPX,ARTN,TACC2,SH3BP1,ANKRD12,TUBG1,IFIT1,TECR,WBP4,PLK1,PPIF,VPS11,PFKFB2,PTPN9,UTRN,KIF1C,CD40,HSF4,BMP1,B4GALT3,ARHGAP4,RAP1GAP,PPP2R5D,PINK1,CALB2,HAL,RASSF7,C6orf106,EFNB1,ITGA2B,SAC3D1,RABGGTA,M6PR,RAC2,ANK1,ITGA3,ADRBK1,MGAT1,CTSC,LYPD3,LLGL2,CD22,BDH1,FDXR,TBCD,ADAM15,ARVCF,CLIP2,RIMS2,GPR161,POU6F1,WNT10B,PCBP3,TCF7,ZSCAN12,AKAP3,PRRC1,MAPK8IP1,CDK5R1,MMP15,RGS9,SLC6A6,TIMP3,ACVRL1,SEMA4D,CSF1,SLC4A3,E2F1,S100A5,MPP2,CCDC69,PLIN3,ESPL1,AFAP1,EHD1,CD33,XDH |
| 4.437e-03 | -5.42 | B41 | smart domains | SM00295 | 51 | 16 | 9131 | 1455 |
FRMPD3,EPB41L5,FARP1,FRMD4A,NF2,FRMD6,EZR,FRMD4B,PLEKHH2,JAK1,EPB41L4B,EPB41L4A,TLN2,MYLIP,JAK3,FARP2 |
| 4.439e-03 | -5.42 | Hurthle_cell_adenoma | COSMIC cancer mutations | Hurthle_cell_adenoma | 28 | 10 | 17775 | 2585 |
TRIM24,AKT1,CCDC6,PTEN,RET,PIK3CA,TFG,IDH1,KTN1,PRKAR1A |
| 4.439e-03 | -5.42 | lip | COSMIC cancer mutations | lip | 28 | 10 | 17775 | 2585 |
AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,NOTCH2,FLT3,EGFR |
| 4.439e-03 | -5.42 | thyroid-adenoma-nodule-goitre-Hurthle_cell_adenoma | COSMIC cancer mutations | thyroid-adenoma-nodule-goitre-Hurthle_cell_adenoma | 28 | 10 | 17775 | 2585 |
TRIM24,AKT1,CCDC6,PTEN,RET,PIK3CA,TFG,IDH1,KTN1,PRKAR1A |
| 4.441e-03 | -5.42 | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_DN | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_DN | 193 | 42 | 17758 | 2588 |
CASP3,FAM189A2,DAP,ARHGEF7,BLVRB,ARL4C,C6orf106,BCL2L1,TSPAN17,LBR,TTC21B,APLP2,SPP1,CCNA2,MKRN3,CST3,C10orf54,NCOA2,CAMK2G,SMAGP,HCN3,MAP3K3,FADS2,TRIM8,IFITM3,ATP8B3,PRRC1,BLVRA,ANLN,CDK1,GINS4,NUDT16,LDLRAP1,RCBTB2,CORO1C,BMP1,PPM1H,IRF7,ALG2,UBE2C,SNX30,NGEF |
| 4.441e-03 | -5.42 | GSE3982_CTRL_VS_LPS_4H_MAC_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_4H_MAC_DN | 193 | 42 | 17758 | 2588 |
CD99,ELK4,DYRK3,AGRN,HERC5,BCL2L1,SPSB1,BTG3,ZFX,CYP1A1,ITGB8,SP100,RRBP1,ATP13A3,IRF2,NFKB2,TIPARP,APOBEC3G,TMX1,LAMP3,CD55,USP18,EZR,RUNX3,ERP44,BLVRA,CD40,CYB5A,FAS,SLCO4A1,CASP7,PVRL2,STAT1,TDRD7,PITPNA,IFIH1,F2RL1,HIPK3,NDST3,MAFF,MIIP,IRF1 |
| 4.441e-03 | -5.42 | GSE17721_CTRL_VS_CPG_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_8H_BMDM_DN | 193 | 42 | 17758 | 2588 |
RUNX2,AGRN,PARP14,KLHL13,RASA2,RGS20,DNAJB11,CCNL1,BCL2L1,APPBP2,ST5,ADORA1,IGSF9,LYPD3,KCNN4,LMO4,LHX6,PLK4,CDH3,TAGLN2,NOTCH3,MYLIP,CYP1B1,RIPK2,PLSCR1,LAP3,SALL4,ARFRP1,PRRC1,ABR,TXK,MAPKAPK2,INSR,PPP2R5A,RBM47,HOXA9,NFKBIA,HDAC1,B4GALT3,AKIP1,TTC39C,PTGES |
| 4.441e-03 | -5.42 | GSE17721_0.5H_VS_12H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_12H_CPG_BMDM_UP | 193 | 42 | 17758 | 2588 |
SUN1,GNPDA1,ITGA6,GMPR,FAM198B,SEPT4,EFNB1,LBR,SS18,OXCT1,GNB5,SH3BP1,MAGEE1,SIVA1,PLCG2,DDHD2,SORL1,IRF2,STT3B,C10orf54,ETHE1,EEF1D,EPHX1,SEC61B,CENPA,ITCH,UBAC1,STX3,ZMPSTE24,FUCA1,GALNT3,ALDH3B1,TIMM8A,DOLPP1,PLA2G15,ARRB1,MDH1,RELL1,MYL12B,RAB3IL1,JARID2,FAM134B |
| 4.441e-03 | -5.42 | Interferon alpha/beta signaling | REACTOME pathways | R-HSA-909733 | 68 | 19 | 8202 | 1235 |
MX1,IFITM3,HLA-E,HLA-F,USP18,IFIT3,HLA-A,SOCS3,HLA-B,JAK1,STAT1,IRF2,IRF7,HLA-C,OAS3,RNASEL,IFIT1,IFI6,IRF1 |
| 4.442e-03 | -5.42 | RICKMAN_METASTASIS_DN | MSigDB lists | RICKMAN_METASTASIS_DN | 244 | 51 | 17758 | 2588 |
GAS2L1,AVPI1,TXN,S100A11,NDRG1,FXYD3,CCM2,TAP1,IL18,BCL2L1,SDC1,ADAMTSL4,S100A2,TNFSF9,PRRG4,LMNA,SGPL1,NPM2,TYMP,VASP,ZDHHC12,A4GALT,CAPG,DNM2,TNPO2,ADAM15,MAPK11,OSTF1,TAGLN2,FLOT2,ALS2CL,S100A6,IGSF3,ATG4D,PVRL4,PRODH,RHOA,C15orf39,ZBTB7B,RNF19B,MAPKAPK2,PTGS2,KCNK1,CORO1C,SECTM1,NLRC5,SH3GLB2,RGS14,SLC27A3,PROM2,MAPK12 |
| 4.450e-03 | -5.41 | MODULE_568 | MSigDB lists | MODULE_568 | 70 | 19 | 17758 | 2588 |
LAMP2,B3GALT6,SYPL1,PLSCR1,FAM189A2,TUBB4B,SLC25A13,TMX4,PARP4,ASAH1,TRIB2,FRMD4B,BTG1,ATP1A1,KCNN4,FBXO7,IRF2,MAD2L1BP,RPGR |
| 4.450e-03 | -5.41 | RAMALHO_STEMNESS_DN | MSigDB lists | RAMALHO_STEMNESS_DN | 70 | 19 | 17758 | 2588 |
BIN1,PAPSS2,CTSB,CYFIP2,FAM101B,ABR,SIRPA,MESDC2,B4GALNT1,NIN,PPP2R5A,ACVRL1,CST3,BMP1,RGS14,NCAM1,PACSIN1,RTN3,CBX4 |
| 4.450e-03 | -5.41 | REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE | MSigDB lists | REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE | 70 | 19 | 17758 | 2588 |
RIPK2,MAPKAPK3,TAB3,RPS6KA1,DUSP4,ELK1,FOS,CDK1,MAPKAPK2,RPS6KA2,IRAK1,NFKBIA,NOD2,MAPK11,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 4.484e-03 | -5.41 | DERL2 (derlin 2) | protein interactions | 51009 | 34 | 12 | 16036 | 2547 |
ERLEC1,FAF2,MFI2,SERPINA1,AMFR,UBE2J1,EMC2,SARAF,RPN2,ESYT1,POR,VCP |
| 4.484e-03 | -5.41 | UBXN11 (UBX domain protein 11) | protein interactions | 91544 | 34 | 12 | 16036 | 2547 |
RND3,ALPP,TRAF2,PRKAA1,CFAP206,AES,NCKAP1,CYFIP2,VCP,SH2D4A,ZFYVE9,RND1 |
| 4.485e-03 | -5.41 | intrinsic component of organelle membrane | cellular component | GO:0031300 | 271 | 56 | 17570 | 2579 |
SUN1,CCDC109B,PINK1,ARMCX3,LFNG,HLA-E,HLA-F,APOO,TAP1,P2RX7,SLC8B1,QSOX2,LBR,BCAP31,CHST2,HLA-A,SGPL1,B4GALNT1,CALR,PQLC2,ENTPD4,STIM1,A4GALT,RRBP1,STEAP2,ABCD1,ECE1,HLA-C,TECR,P2RX4,SUN2,SYPL1,QSOX1,TMEM43,AMFR,EMC2,SYP,ESYT1,LEMD2,HLA-B,TAPBP,DOLPP1,WFS1,PEX2,CSGALNACT1,DGAT2,TRABD2A,SARAF,PKD2,SAMD8,MCUR1,B4GAT1,ST3GAL1,ESYT2,DMPK,FAM134B |
| 4.486e-03 | -5.41 | human chr3q26.3 | chromosome location | human chr3q26.3 | 4 | 3 | 26250 | 2805 |
DCUN1D1,PRKCI,PIK3CA |
| 4.489e-03 | -5.41 | AAGCACT,MIR-520F | MSigDB lists | AAGCACT,MIR-520F | 227 | 48 | 17758 | 2588 |
SPRED1,GRHL2,EPAS1,XYLT1,PBX3,PLXNA1,FAM46C,PPP2R3A,TFAP4,CCND1,UBE2Q2,RALGPS2,IL6ST,FRAS1,LYPD6,OCRL,LHX6,PRC1,TUBG1,H2AFY,CDKN1B,IRF2,NTN4,TIPARP,CPD,CYP26B1,ZNF462,PCGF5,TMTC1,CXXC5,DCAF6,ANO6,VAMP3,KBTBD8,FNDC3A,NFIB,MUM1L1,ABR,CRTC2,CDK19,RBL1,NR4A3,AGFG2,YOD1,ABCA1,ARHGEF9,NR2C2,RGMA |
| 4.505e-03 | -5.40 | Pancreatic cancer | KEGG pathways | ko05212 | 66 | 19 | 6908 | 1076 |
AKT1,RALBP1,PIK3R1,CASP9,TP53,ERBB2,TGFBR1,BCL2L1,EGFR,CCND1,RAC2,RB1,JAK1,RALB,E2F1,PIK3CA,STAT1,PIK3CD,PLD1 |
| 4.505e-03 | -5.40 | Pancreatic cancer | KEGG pathways | hsa05212 | 66 | 19 | 6908 | 1076 |
AKT1,RALBP1,PIK3R1,CASP9,TP53,ERBB2,TGFBR1,BCL2L1,EGFR,CCND1,RAC2,RB1,JAK1,RALB,E2F1,PIK3CA,STAT1,PIK3CD,PLD1 |
| 4.509e-03 | -5.40 | BIOCARTA_HDAC_PATHWAY | MSigDB lists | BIOCARTA_HDAC_PATHWAY | 28 | 10 | 17758 | 2588 |
CALM2,INSR,IGF1R,AKT1,CALM1,PIK3R1,PIK3CA,CALM3,CABIN1,MAPK7 |
| 4.509e-03 | -5.40 | AIYAR_COBRA1_TARGETS_DN | MSigDB lists | AIYAR_COBRA1_TARGETS_DN | 28 | 10 | 17758 | 2588 |
CPD,ZNF395,PRDX3,METTL7A,CLDN4,APIP,HSPB1,SLC20A1,PRX,MYO5C |
| 4.514e-03 | -5.40 | MODULE_122 | MSigDB lists | MODULE_122 | 138 | 32 | 17758 | 2588 |
CD99,COL9A3,SELL,COL18A1,IL18,COL4A5,APBA1,EFNB1,ICAM1,RND1,NEO1,ZYX,ITGA3,CTGF,SRPX,CDH1,COL6A1,CDH3,NCAM1,COL6A2,COL7A1,ARHGDIB,ALCAM,COL12A1,CNTNAP1,PTPRF,DGCR2,RND3,PTK7,ITGAV,COL16A1,L1CAM |
| 4.514e-03 | -5.40 | TTGGAGA,MIR-515-5P,MIR-519E | MSigDB lists | TTGGAGA,MIR-515-5P,MIR-519E | 138 | 32 | 17758 | 2588 |
ARHGEF3,IQGAP1,ABCG4,NOTCH2,PM20D2,ETS1,CMTM6,NCS1,SLC9A2,SGPL1,UBE2Q2,KHNYN,CYR61,FRAS1,OSBPL3,FAM84B,CLIP2,MOSPD2,TACC1,WHSC1,NFIB,ULK2,SP4,DGCR2,SLC4A4,FGFR2,CSNK1G1,RAP2C,CAB39,DONSON,CPEB2,RPS6KA3 |
| 4.519e-03 | -5.40 | myelin maintenance | biological process | GO:0043217 | 12 | 6 | 16441 | 2455 |
MPP5,SOD1,FA2H,AKT1,PTEN,NDRG1 |
| 4.519e-03 | -5.40 | branching involved in labyrinthine layer morphogenesis | biological process | GO:0060670 | 12 | 6 | 16441 | 2455 |
GRHL2,FZD5,FGFR2,ST14,SPINT2,SOCS3 |
| 4.535e-03 | -5.40 | BOUDOUKHA_BOUND_BY_IGF2BP2 | MSigDB lists | BOUDOUKHA_BOUND_BY_IGF2BP2 | 106 | 26 | 17758 | 2588 |
KIF3C,PSRC1,SEC61B,SERPINE2,NDRG1,IQGAP1,EPS8,FTH1,MAP1LC3B,PCBP1,LBR,PSIP1,VPS26A,CCND1,NAPG,UAP1,TIMM8A,CSF1,UBE2D2,RAB31,KLF9,MARCH2,RPL22,CD81,S100A6,CRTAP |
| 4.550e-03 | -5.39 | response to fluid shear stress | biological process | GO:0034405 | 36 | 12 | 16441 | 2455 |
P2RX4,PTGS2,KLF2,SPP1,CA2,AKT1,P2RX7,PKD2,CITED2,MAPK7,ETS1,ABCA1 |
| 4.550e-03 | -5.39 | regulation of centrosome cycle | biological process | GO:0046605 | 36 | 12 | 16441 | 2455 |
CENPJ,PLK2,NEK2,VPS4B,PLK4,AURKA,XRCC3,CHMP4B,CCNF,KIF11,NUBP1,GEN1 |
| 4.576e-03 | -5.39 | V$OCT1_07 | MSigDB lists | V$OCT1_07 | 149 | 34 | 17758 | 2588 |
NUDT6,FRMD4A,GRHL2,SCOC,CPEB4,SLC25A13,IRX4,CDK14,NEO1,HDAC9,CCND1,FOXP2,ADD3,IRAK1,RALGPS2,XYLT2,LMO4,DIXDC1,MYT1,BTBD3,PLEKHA6,MBP,ASXL1,FZD4,SERTAD4,LYRM1,LDB2,TMTC2,NFIX,FGFR2,NEIL3,CSNK1G1,TMOD2,TOB1 |
| 4.576e-03 | -5.39 | NEGATIVE_REGULATION_OF_APOPTOSIS | MSigDB lists | NEGATIVE_REGULATION_OF_APOPTOSIS | 149 | 34 | 17758 | 2588 |
CASP3,ACVR1,HSP90B1,SERPINB9,XIAP,NOTCH2,BCL2L1,GSTP1,BARD1,IER3,IGF1R,BAX,TNFRSF18,PIM1,CDKN2D,TMX1,SOD1,BAG4,GCLC,BNIP3L,HTATIP2,GLO1,CDK1,RASA1,BCL10,SOCS3,FAS,SCG2,SEMA4D,HDAC1,HSPB1,HIPK3,IFI6,CBX4 |
| 4.588e-03 | -5.38 | HERC5 (HECT and RLD domain containing E3 ubiquitin protein ligase 5) | protein interactions | 51191 | 26 | 10 | 16036 | 2547 |
PITX2,CCND1,CCNA2,CTNNB1,STK38,RANBP1,TP53,HERC5,ERCC2,CCNB1 |
| 4.588e-03 | -5.38 | RABL6 (RAB, member RAS oncogene family-like 6) | protein interactions | 55684 | 26 | 10 | 16036 | 2547 |
NKX3-1,CDKL5,PLK2,TP53,BUB1,MYH14,MYL12A,NUP85,SMC4,MDFI |
| 4.588e-03 | -5.38 | MIS12 (MIS12 kinetochore complex component) | protein interactions | 79003 | 26 | 10 | 16036 | 2547 |
ZWINT,SERPINA1,CENPC,SPC25,NDC80,NUF2,BUB1,SKA1,CBX5,MAFF |
| 4.588e-03 | -5.38 | SPTA1 (spectrin, alpha, erythrocytic 1) | protein interactions | 6708 | 26 | 10 | 16036 | 2547 |
NCOA3,VASP,ANK1,ADD1,UBASH3B,MYBL2,EZR,CBL,SPTB,SLC9A2 |
| 4.589e-03 | -5.38 | TBK1 (TANK-binding kinase 1) | protein interactions | 29110 | 93 | 25 | 16036 | 2547 |
DDX58,HMMR,NLRP4,MBP,TNIP1,AKT1,TRAF2,RNF11,XIAP,CUL1,FXR2,IFIT3,MAP1LC3B,STX3,EGFR,OPTN,SOCS3,NFKBIA,DTX4,IRF7,NFKB2,PPP6R1,SYK,NCOA2,TMEM173 |
| 4.590e-03 | -5.38 | peptidyl-serine modification | biological process | GO:0018209 | 135 | 32 | 16441 | 2455 |
PRKAA2,PINK1,PRKAA1,TGFBR1,CCNB1,PRKACA,PDGFB,RPS6KA2,ADRBK1,PAK2,SGK3,SGK1,MAPK7,MAST4,SYK,PLK1,AKT1,MAPKAPK3,AURKB,PDK3,ILK,CDK1,CDK5R1,GALNT3,MAPKAPK2,CSNK1G1,AURKA,STK39,MAPK13,HIPK3,MAPK12,DMPK |
| 4.594e-03 | -5.38 | human chr3q22.3 | chromosome location | human chr3q22.3 | 16 | 6 | 26250 | 2805 |
MRAS,FAIM,CEP70,SLC35G2,DZIP1L,DBR1 |
| 4.598e-03 | -5.38 | organic hydroxy compound metabolic process | biological process | GO:1901615 | 487 | 94 | 16441 | 2455 |
PLA2G4A,EPAS1,CRYM,INPP5D,PHOSPHO1,GATA3,PLA2G16,LPIN3,CYP39A1,EPM2A,PER2,CDS1,CALM2,INPP5E,APLP2,CYP1A1,IMPAD1,ALDH1A3,PLCG2,RDH14,SLC44A1,FABP6,AKR1B1,TRPC1,GOT1,ACOX2,MINPP1,LGMN,CYP1B1,SOAT1,PFKFB2,CYB5R2,PNKD,CYP4F3,POR,SLC44A3,SGPP1,PLCH1,ALDH3B1,DUOX1,PLCG1,PEX2,INPP4B,PNPLA6,MAOA,SLC27A1,PDXK,ITPKA,CHPT1,ABCA1,PRKAA2,GALK1,INPPL1,PRKAA1,CALM3,ISYNA1,SPR,DHRS3,LBR,PTEN,OCRL,FDXR,ATP8B1,SORL1,SLC44A2,ALDH7A1,TTPA,PLCB2,ALDH3A2,MYO5A,NCOA2,SHMT1,ALDH2,CALM1,NPC2,SPTLC2,PCTP,LEPR,GPLD1,FECH,SLCO4A1,LDLRAP1,PRKAG2,CTNS,HTT,DBI,PLA2G15,DGAT2,NR4A2,SAMD8,ACADM,APOL2,ABCG1,DRD1 |
| 4.598e-03 | -5.38 | positive regulation of protein dephosphorylation | biological process | GO:0035307 | 45 | 14 | 16441 | 2455 |
CALM2,BMP2,PINK1,ADORA1,PPP2R5A,PPP1R12A,NPNT,CALM1,PPP2R4,CALM3,CDCA2,SLC39A10,CNEP1R1,GPLD1 |
| 4.598e-03 | -5.38 | autonomic nervous system development | biological process | GO:0048483 | 45 | 14 | 16441 | 2455 |
HES1,CTNNB1,TBX1,RET,TFAP2A,GATA3,ERBB2,SOX8,KIF26A,SEMA3A,HOXB2,NRP2,GBX2,EDNRA |
| 4.600e-03 | -5.38 | PTPN13 (protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)) | protein interactions | 5783 | 30 | 11 | 16036 | 2547 |
CTNNB1,NGFRAP1,RAPGEF2,CRIP2,NFKBIA,DNM2,WHSC1,BRD7,PRKACA,EFNB1,FAS |
| 4.600e-03 | -5.38 | IL2RG (interleukin 2 receptor, gamma) | protein interactions | 3561 | 30 | 11 | 16036 | 2547 |
PTPRJ,JAK1,IL15RA,IL15,STAT1,CAPNS1,IL13RA1,WWP1,JAK3,ICAM1,WWP2 |
| 4.603e-03 | -5.38 | response to unfolded protein | biological process | GO:0006986 | 151 | 35 | 16441 | 2455 |
FAF2,HSP90B1,ADD1,SEC61G,DNAJB2,JKAMP,DNAJC3,PDIA5,DNAJB11,FBXO6,DNAJB9,LMNA,CCND1,CALR,BAX,TMBIM6,DAB2IP,STT3B,MYDGF,MANF,PDIA6,HSPA2,CTDSP2,CTH,GFPT1,SEC61B,AMFR,ERO1A,KDELR3,ERP44,VCP,WIPI1,WFS1,YOD1,HSPB1 |
| 4.606e-03 | -5.38 | PI-3K cascade:FGFR4 | REACTOME pathways | R-HSA-5654720 | 98 | 25 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.606e-03 | -5.38 | PIP3 activates AKT signaling | REACTOME pathways | R-HSA-1257604 | 98 | 25 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,PDGFA,IRS2,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,ERBB3,PIK3CD,GAB1 |
| 4.606e-03 | -5.38 | PI-3K cascade:FGFR2 | REACTOME pathways | R-HSA-5654695 | 98 | 25 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.606e-03 | -5.38 | PI3K events in ERBB2 signaling | REACTOME pathways | R-HSA-1963642 | 98 | 25 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.606e-03 | -5.38 | PI3K events in ERBB4 signaling | REACTOME pathways | R-HSA-1250342 | 98 | 25 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.606e-03 | -5.38 | PI-3K cascade:FGFR1 | REACTOME pathways | R-HSA-5654689 | 98 | 25 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.606e-03 | -5.38 | PI-3K cascade:FGFR3 | REACTOME pathways | R-HSA-5654710 | 98 | 25 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 4.608e-03 | -5.38 | HALLMARK_XENOBIOTIC_METABOLISM | MSigDB lists | HALLMARK_XENOBIOTIC_METABOLISM | 199 | 43 | 17758 | 2588 |
PINK1,PAPSS2,NQO1,DHPS,CYP2J2,BLVRB,ASL,NDRG2,FBLN1,CYP26A1,CYP1A1,CA2,CYP2S1,AOX1,TPST1,TMBIM6,AHCY,ACOX2,GAD1,TTPA,MCCC2,FAH,EPHX1,ALDH2,GCLC,CDA,CYFIP2,BCAR1,IDH1,POR,CYB5A,FAS,GABARAPL1,IL1R1,SLC6A6,ETS2,SPINT2,PGRMC1,MPP2,MAOA,RAP1GAP,PTGES,XDH |
| 4.608e-03 | -5.38 | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN | 199 | 43 | 17758 | 2588 |
TXN,AGRN,S100A11,AASS,NDRG1,SOX9,CUL1,DUSP5,ICAM1,NRP2,GBX2,IER3,ATG4A,TYMP,CDH1,LYPD3,FICD,ANKRD12,MANF,RASGRP1,PSMA5,CKAP4,MCCC2,SEC61B,TNIP1,SNTB2,LITAF,AK4,RUNX3,AURKB,RNF19B,LHFPL2,CYB5A,CD83,HSF4,TAPBP,SCARB2,FGFR2,WIPI1,NFKBIA,NR4A3,IFI6,COBL |
| 4.641e-03 | -5.37 | V$ELK1_01 | MSigDB lists | V$ELK1_01 | 256 | 53 | 17758 | 2588 |
LZTFL1,PAX6,CPEB4,CAST,DGKA,BCL2L1,CNTROB,DPP8,TEAD3,SIRPA,DNAJB9,VASP,CES2,LLGL2,PPME1,CKS1B,TAGLN2,PPP1CA,CNOT6L,CITED2,PSMA5,RBMS2,VPS11,TAF5,ELK3,CRB3,STAT4,VPS4B,RGAG1,DBR1,FURIN,TCF7,ARHGDIB,NKAIN1,ZBTB7B,FOS,LCP1,CRTC2,ENPP1,FYN,PLEKHH2,TBC1D17,PRKAG2,FNTA,KLF12,SH2D3C,RAP2C,EGFL7,GEN1,STARD13,LIFR,ARHGEF4,PCSK5 |
| 4.645e-03 | -5.37 | Metabolism of lipids and lipoproteins | REACTOME pathways | R-HSA-556833 | 628 | 118 | 8202 | 1235 |
PLA2G4A,CCNC,MTM1,ACACB,HSPG2,CPT2,INPP5D,PNPLA2,HEXB,ETNK1,PHOSPHO1,PLA2G16,LPIN3,CDIPT,SDC1,PRKACA,ECI1,CYP39A1,CDS1,HELZ2,INPP5E,CYP1A1,CTGF,GRHL1,CYP4F11,P4HB,SLC44A1,FABP6,PIK3CA,AKR1B1,PIK3CD,ACOX2,ACSL4,PPP1CA,TECR,LGMN,FAR1,MED30,GM2A,CERS2,GPX4,CYP1B1,SEC23A,AGPS,IDH1,CYP4F3,SGPP1,SLC44A3,KDSR,PTGS2,ALDH3B1,PI4K2B,AGPAT2,CDK19,ACAD10,WWTR1,INPP4B,BMP1,PPP1CB,SLC27A1,PIK3C2B,CYP2U1,GLA,LTA4H,CHPT1,ABCA1,PRKAA2,FAM213B,INPPL1,CDS2,CYP2J2,ELOVL7,ASAH1,PLD2,LBR,TEAD3,SGPL1,OXCT1,PTEN,ARSG,OCRL,BDH1,FDXR,SLC44A2,ABCD1,HMGCL,FAR2,PIKFYVE,ALDH3A2,NCOA2,MED22,ABCC1,FADS2,PCCB,LPGAT1,PIK3R1,ELOVL3,PPARA,FHL2,SPTLC2,ARSK,CPTP,MAPKAPK2,NCOA3,PRKAG2,LDLRAP1,FA2H,FAAH,PLPP3,DGAT2,CTSA,GLB1,ACADM,PLD1,ARSB,PTGES,ACOT7,ABCG1 |
| 4.660e-03 | -5.37 | Regulation of mitotic cell cycle | REACTOME pathways | R-HSA-453276 | 83 | 22 | 8202 | 1235 |
PLK1,PSMB4,PSME2,PTTG1,CDC20,PSMD7,CUL1,PSMD10,PSME1,AURKB,CCNB1,CDK1,PSMA4,CCNA2,PSMD1,PSMD3,PSMC2,NEK2,AURKA,UBE2C,PSMC1,PSMA5 |
| 4.660e-03 | -5.37 | APC/C-mediated degradation of cell cycle proteins | REACTOME pathways | R-HSA-174143 | 83 | 22 | 8202 | 1235 |
PLK1,PSMB4,PSME2,PTTG1,CDC20,PSMD7,CUL1,PSMD10,PSME1,AURKB,CCNB1,CDK1,PSMA4,CCNA2,PSMD1,PSMD3,PSMC2,NEK2,AURKA,UBE2C,PSMC1,PSMA5 |
| 4.661e-03 | -5.37 | MODULE_532 | MSigDB lists | MODULE_532 | 373 | 73 | 17758 | 2588 |
ACVR1,AASS,MRPS15,TP53,MAPK4,CCNL1,NANS,BAIAP3,CMTM6,C1orf116,CYP1A1,RNF220,METTL7A,PAQR5,ESPN,PDE4D,EPB41L4B,SCARA3,ATG4D,TUBA4A,TMCC2,TDP1,TCEB2,LAP3,TMEM144,SLC11A2,PIF1,SAV1,MYL12A,TRIM7,KDM4D,AMZ2,PTGS2,PI4K2B,NEIL1,MPRIP,PLEKHG1,RNASEL,RRAGD,LMTK3,FAM169A,SLC25A27,C6orf106,ISYNA1,IL18R1,C9orf69,CDK16,TMEM62,CITED2,FAIM,CNOT6L,ITM2C,MOB4,HMGN5,TBC1D8B,ADCK3,FMN1,MICB,FURIN,PIP4K2C,BCL2L13,FOS,BSDC1,CD8A,CSF1,WDR19,S100A5,FGD6,NXPH4,MAL2,GEM,TMEM120A,C17orf75 |
| 4.664e-03 | -5.37 | vagina | COSMIC cancer mutations | vagina | 16 | 7 | 17775 | 2585 |
CTNNB1,AKT1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 4.664e-03 | -5.37 | soft_tissue-fat-liposarcoma-pleomorphic | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-pleomorphic | 16 | 7 | 17775 | 2585 |
RB1,CTNNB1,CDH1,IDH1,PTEN,PIK3CA,TP53 |
| 4.664e-03 | -5.37 | serrated_polyp | COSMIC cancer mutations | serrated_polyp | 16 | 7 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA,TP53 |
| 4.664e-03 | -5.37 | large_intestine-colon-serrated_polyp-serrated_adenoma | COSMIC cancer mutations | large_intestine-colon-serrated_polyp-serrated_adenoma | 16 | 7 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA,TP53 |
| 4.664e-03 | -5.37 | neurocristic_hamartoma | COSMIC cancer mutations | neurocristic_hamartoma | 16 | 7 | 17775 | 2585 |
CTNNB1,AKT1,IDH1,PTEN,EGFR,PIK3CA,TP53 |
| 4.664e-03 | -5.37 | central_nervous_system-brain-glioma-ependymoma_Grade_III-IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_III-IV | 16 | 7 | 17775 | 2585 |
TSC1,RB1,NF2,AKT1,IDH1,PTEN,TP53 |
| 4.664e-03 | -5.37 | skin-other-neurocristic_hamartoma | COSMIC cancer mutations | skin-other-neurocristic_hamartoma | 16 | 7 | 17775 | 2585 |
CTNNB1,AKT1,IDH1,PTEN,EGFR,PIK3CA,TP53 |
| 4.664e-03 | -5.37 | tubular | COSMIC cancer mutations | tubular | 16 | 7 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA,TP53 |
| 4.664e-03 | -5.37 | serrated_adenoma | COSMIC cancer mutations | serrated_adenoma | 16 | 7 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA,TP53 |
| 4.671e-03 | -5.37 | Heparan sulfate/heparin (HS-GAG) metabolism | REACTOME pathways | R-HSA-1638091 | 54 | 16 | 8202 | 1235 |
B3GALT6,SLC35D2,AGRN,HSPG2,GUSB,SDC4,SDC1,EXT2,GLCE,HS6ST1,HPSE,GPC3,GLB1,HS3ST3B1,NDST3,HS6ST3 |
| 4.691e-03 | -5.36 | GSK3B (glycogen synthase kinase 3 beta) | protein interactions | 2932 | 273 | 60 | 16036 | 2547 |
KLF2,PPP1R2,ARHGEF11,TRAF2,RPS6KA1,XIAP,TP53,NOTCH2,PHLPP1,HDAC6,PRKACA,GNB2,EPM2A,TOP2A,CCND1,KIF5B,RNF220,CTNNB1,CDH1,DPYSL2,LMO4,BHLHE41,MITF,SGK3,SGK1,GYS1,NOTCH3,PPP1CA,PDE4D,UPF3A,TRAK2,CAMSAP3,AKT1,MPP1,PIK3R1,NUB1,NFE2L1,ILK,MAP1B,NIN,TSC1,NCOA3,MID1IP1,DNM1L,ANKRD6,DBI,MAP3K11,FAM83D,E2F1,ARRB1,TLE1,GSKIP,AURKA,KLF5,CTNND1,RCAN2,FZD5,PPP2R5D,NRBP1,PRKAR1A |
| 4.696e-03 | -5.36 | TNF signaling pathway | KEGG pathways | hsa04668 | 110 | 28 | 6908 | 1076 |
CASP3,BAG4,AKT1,IL15,TAB3,ITCH,TRAF2,PIK3R1,FOS,IL18R1,ICAM1,FAS,SOCS3,PTGS2,CASP7,DNM1L,CSF1,NFKBIA,NOD2,PIK3CA,MAPK11,MAPK13,MLKL,PIK3CD,MAP3K7,MAP3K5,TRAF5,MAPK12 |
| 4.696e-03 | -5.36 | TNF signaling pathway | KEGG pathways | ko04668 | 110 | 28 | 6908 | 1076 |
CASP3,BAG4,AKT1,IL15,TAB3,ITCH,TRAF2,PIK3R1,FOS,IL18R1,ICAM1,FAS,SOCS3,PTGS2,CASP7,DNM1L,CSF1,NFKBIA,NOD2,PIK3CA,MAPK11,MAPK13,MLKL,PIK3CD,MAP3K7,MAP3K5,TRAF5,MAPK12 |
| 4.700e-03 | -5.36 | ovary-low_malignant_potential_(borderline)_tumour-mucinous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-mucinous | 37 | 12 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 4.700e-03 | -5.36 | Activation of Ca-permeable Kainate Receptor | REACTOME pathways | R-HSA-451308 | 12 | 6 | 8202 | 1235 |
CALM3,CALM2,DLG3,GRIK2,CALM1,DLG1 |
| 4.700e-03 | -5.36 | Ionotropic activity of Kainate Receptors | REACTOME pathways | R-HSA-451306 | 12 | 6 | 8202 | 1235 |
CALM3,CALM2,DLG3,GRIK2,CALM1,DLG1 |
| 4.700e-03 | -5.36 | eNOS activation | REACTOME pathways | R-HSA-203615 | 12 | 6 | 8202 | 1235 |
CALM2,CALM3,DDAH1,AKT1,CALM1,ZDHHC21 |
| 4.706e-03 | -5.36 | GSE17721_CTRL_VS_POLYIC_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_12H_BMDM_UP | 188 | 41 | 17758 | 2588 |
UPF3B,NF2,HEBP1,FAM134A,DNAJB9,FAM111A,TM9SF2,ELMO2,SLC16A6,IL6ST,BDH1,N4BP3,FAM63A,TAX1BP3,TECR,CASD1,FAR1,MPHOSPH9,CRTAP,MSH6,MBP,PTPN18,FBXO8,ARHGDIB,FAM73B,CDC25C,FANCE,PNKD,SKA1,NUCB1,RPL12,FASTKD1,CTNS,SLC25A4,FAM64A,WIPI1,CTSA,MDH1,PDXK,CD81,GLCCI1 |
| 4.706e-03 | -5.36 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP | 188 | 41 | 17758 | 2588 |
SIGIRR,ST13,ITGA6,GATA3,GTF3A,TRIB2,LTBP3,DENND2D,PSIP1,TGFBR3,OXCT1,GNB5,PASK,FAM102A,MYBL1,MAST4,RASGRP1,FAM69A,GCC2,SOD1,SEPT6,STAT4,SYNE2,TCF7,PRKCQ,ITPR3,PLEKHB1,TXK,PLCG1,LDLRAP1,NGFRAP1,UBE2D2,FHL1,TBC1D4,TRAF5,SLC25A38,CBX7,PKIA,DOCK9,PHC1,FAM134B |
| 4.706e-03 | -5.36 | GSE17721_CTRL_VS_PAM3CSK4_4H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_4H_BMDM_UP | 188 | 41 | 17758 | 2588 |
MRPL44,CHCHD7,SMARCAL1,ABCG2,TP53,NDUFA4,RACGAP1,SEPP1,PRKACA,CMTM6,XPR1,SLC25A45,DOPEY2,PCNA,RDH14,GYS1,IRF2,BUB1,HMGCL,CNOT6L,HP1BP3,EPB41L5,MX1,TDP1,PRODH,LGALS8,LPGAT1,CORO2A,KIF1C,MRPS35,ANLN,C4orf27,ACADSB,MTFMT,TMEM30A,PLA2G15,ITPR1,ARRB1,ALG2,ITPKA,CPPED1 |
| 4.706e-03 | -5.36 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN | 188 | 41 | 17758 | 2588 |
DLGAP5,CD63,FOXM1,SEC61G,PTTG1,ETNK1,PSMD7,GPSM2,GSTP1,PHLDA1,COX7A2,FANCI,PDIA4,UHRF1BP1L,TOP2A,BTG3,CA2,OXCT1,KCNK5,RNASEH2A,ETHE1,WBP4,ALDH3A2,SMC4,NFE2L3,GGH,RAB38,CDK1,DCTN6,PRDX3,PSMD3,CSF1,RAB11FIP1,FGD6,MAOA,AURKA,PRKCDBP,XRCC3,CCNB2,ESPL1,ACOT7 |
| 4.706e-03 | -5.36 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | 188 | 41 | 17758 | 2588 |
AVPI1,NFKBIE,LGR4,HEBP1,IL13RA1,TRIB2,HERC6,DNAH3,PGAP1,CARD10,LTBP3,RPS6KA2,FAM46A,CTGF,TIMP1,DACT1,RPL39,KLF3,TMBIM6,VAT1,TAGLN2,SMYD5,SULT2B1,MGAT5,NCOA2,ORAI2,MBP,ADCK3,DRAP1,NPC2,ESYT1,NDRG3,BSDC1,CDK5R1,CD83,MAN2A2,CTNND1,FHL1,FZD5,ST3GAL1,MAFF |
| 4.721e-03 | -5.36 | MICROTUBULE_MOTOR_ACTIVITY | MSigDB lists | MICROTUBULE_MOTOR_ACTIVITY | 16 | 7 | 17758 | 2588 |
KIF23,KIF5B,KIF22,KIF2C,CENPE,KIF11,APPBP2 |
| 4.721e-03 | -5.36 | BIOCARTA_IL22BP_PATHWAY | MSigDB lists | BIOCARTA_IL22BP_PATHWAY | 16 | 7 | 17758 | 2588 |
JAK1,JAK3,STAT6,STAT4,IL22RA1,STAT1,SOCS3 |
| 4.721e-03 | -5.36 | BIOCARTA_P53_PATHWAY | MSigDB lists | BIOCARTA_P53_PATHWAY | 16 | 7 | 17758 | 2588 |
CCND1,RB1,PCNA,TIMP3,E2F1,TP53,BAX |
| 4.721e-03 | -5.36 | MITOTIC_SISTER_CHROMATID_SEGREGATION | MSigDB lists | MITOTIC_SISTER_CHROMATID_SEGREGATION | 16 | 7 | 17758 | 2588 |
NUSAP1,CENPE,ZWINT,ESPL1,CDCA5,SMC4,NDC80 |
| 4.721e-03 | -5.36 | BIOCARTA_BCELLSURVIVAL_PATHWAY | MSigDB lists | BIOCARTA_BCELLSURVIVAL_PATHWAY | 16 | 7 | 17758 | 2588 |
CASP3,CASP7,AKT1,FOS,PIK3R1,XIAP,PIK3CA |
| 4.721e-03 | -5.36 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL | 16 | 7 | 17758 | 2588 |
APLP2,GTF3A,S100A11,CEP89,S100A6,PTTG1,RASGRP2 |
| 4.721e-03 | -5.36 | MODULE_315 | MSigDB lists | MODULE_315 | 16 | 7 | 17758 | 2588 |
KIF23,BUB1,CENPE,CCNA2,KIF11,CDC20,TUBA4A |
| 4.721e-03 | -5.36 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | MSigDB lists | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | 16 | 7 | 17758 | 2588 |
CALM2,CALM3,PYGL,PGM1,PHKA2,PHKG2,CALM1 |
| 4.722e-03 | -5.36 | MAPK14 (mitogen-activated protein kinase 14) | protein interactions | 1432 | 220 | 50 | 16036 | 2547 |
PLA2G4A,ELK4,FLYWCH2,IQGAP1,RET,TP53,GATA3,AES,GDF15,TGFBR1,PAK6,RB1,IRAK1,OXCT1,MITF,DUSP10,MAPK11,KIF22,MAP3K7,SLC12A2,PLCB2,NEB,DUSP1,MBP,ELK3,AKT1,CENPC,MAPKAPK3,STAT4,SRSF5,LRRC1,DUSP4,CBL,ELK1,CDC25C,EGFR,MAPKAPK2,HSF4,NCOA3,PI4K2B,TSC1,LIMK1,NFKBIA,STAT1,ARRB1,HDAC1,STK39,RPL22,RPS6KA3,CCDC97 |
| 4.728e-03 | -5.35 | dendrite | cellular component | GO:0030425 | 412 | 80 | 17570 | 2579 |
LAMP1,GRIK2,EPHA4,RET,FBXO2,LYNX1,HDAC6,DNER,GRM5,NCS1,NOV,CDKL5,IL6ST,CABP1,DPYSL2,DAB2IP,PPP1CA,CTTN,DLG3,SGCE,SOD1,PRKAR2B,TANC1,ARF4,GABARAPL1,PIAS3,TRIM9,GRID2IP,MAP2,KCNK1,PLK2,WFS1,SLC9A6,SIPA1L1,STAT1,NRG1,ITPKA,RGS14,NRGN,COBL,LZTS1,ANXA3,LMTK3,TAOK2,SORT1,FARP1,CPEB4,LRP4,STRN4,SLC1A3,CAPN2,ADORA1,MLPH,IGSF9,PTEN,ANKS1B,KNDC1,MAGEE1,CPLX1,HCN3,DPYSL5,P2RX4,MOB4,ZWINT,SHARPIN,GRIN1,FXR2,ILK,ELK1,MAPK8IP1,CDK5R1,STX3,MAP1B,GNAS,HTT,ARRB1,GRIN2D,GPER1,SEMA3A,DRD1 |
| 4.735e-03 | -5.35 | pleomorphic | COSMIC cancer mutations | pleomorphic | 24 | 9 | 17775 | 2585 |
RB1,CTNNB1,CDH1,CHCHD7,PTEN,PIK3CA,TP53,IDH1,EGFR |
| 4.740e-03 | -5.35 | human chr14q22.1 | chromosome location | human chr14q22.1 | 21 | 7 | 26250 | 2805 |
TRIM9,ATL1,FRMD6,KTN1,TMX1,ERO1A,NIN |
| 4.747e-03 | -5.35 | Rho GTPase cycle | REACTOME pathways | R-HSA-194840 | 124 | 30 | 8202 | 1235 |
ARHGAP11A,ARAP2,ARHGEF3,ARAP3,RHOA,ARHGEF11,TRIP10,RALBP1,ARHGEF7,RACGAP1,ARHGDIB,RHOB,ARHGEF16,ABR,SYDE2,ARHGAP35,ARHGAP24,RAC2,OCRL,MCF2L,FAM13B,ARAP1,RHOBTB2,ARHGAP4,TIAM1,STARD13,ARHGEF9,ARHGEF4,FGD1,NGEF |
| 4.770e-03 | -5.35 | CTGAGCC,MIR-24 | MSigDB lists | CTGAGCC,MIR-24 | 222 | 47 | 17758 | 2588 |
PRSS8,OTUD5,SEMA6B,WDTC1,APBA1,SNN,TNFRSF19,MOCS1,PER2,SAP130,REEP1,CDKN1B,PIM1,C8orf58,MAPK7,CLIP2,TMEM9,SMAGP,AMOTL2,NEK4,TMCC2,PHF20L1,TAF5,MLEC,CITED4,PTPN9,RNF11,RNF165,PTGER4,FURIN,WHSC1,STRADB,SYP,SESN1,SFXN5,MAPK8IP1,RASA1,ATP13A2,PTPRF,PLOD2,AMMECR1,RAP2C,SP6,YOD1,RARG,CMTM4,PHC1 |
| 4.782e-03 | -5.34 | DELACROIX_RAR_BOUND_ES | MSigDB lists | DELACROIX_RAR_BOUND_ES | 439 | 84 | 17758 | 2588 |
FAM171B,SIGIRR,SPRED1,SPC25,FAM160B1,TP53,FAM198B,FAM91A1,LACTB2,CAMK1D,PIGL,DENND2D,PICK1,CCND1,WEE1,CDH1,CTGF,SH3BP1,VAT1,STEAP3,RAB20,STK35,SULF2,ATG4D,ENPP4,GCA,MBP,ING1,FIGNL1,SNTB2,DUSP4,DAG1,TRIM7,ARF4,PLEKHB1,SOCS3,MDK,HLF,GDE1,HS3ST3B1,WBSCR27,COBL,OTUD5,KLF2,INPPL1,DYRK3,AES,CTSZ,ZNF219,DHRS3,GBX2,CALR,SPP1,PPP1R10,CST3,ZIC5,NEK2,EBF4,IGFBP2,IQGAP3,CITED2,CTSD,KANK3,SPRY2,MSH6,DUSP1,B3GNT7,STAT4,MYBL2,CAPNS1,PIM3,GRTP1,NFIB,PTPRF,FAM64A,C2orf70,ITPR1,HOXB13,EFNA1,ZMIZ1,WDR91,FOXA1,FAM45A,PHC1 |
| 4.783e-03 | -5.34 | Pro_4_hyd_alph | interpro domains | IPR006620 | 16 | 7 | 18293 | 2672 |
PLOD3,EGLN3,PLOD2,P3H2,P4HA2,P4HA3,EGLN1 |
| 4.783e-03 | -5.34 | SPIRA_SMOKERS_LUNG_CANCER_UP | MSigDB lists | SPIRA_SMOKERS_LUNG_CANCER_UP | 37 | 12 | 17758 | 2588 |
PLA2G4A,ANXA3,CD55,SERPINA1,SLC4A4,SLC39A8,SOX9,UBE2J1,FOS,TRAM1,TOB1,TMED2 |
| 4.783e-03 | -5.34 | MODULE_91 | MSigDB lists | MODULE_91 | 37 | 12 | 17758 | 2588 |
PSMD1,PSMB4,PSME2,PSMD3,PSMC2,UBE2D2,PSMD7,PSMD10,PSME1,PSMC1,PSMA4,PSMA5 |
| 4.783e-03 | -5.34 | GNF2_VAV1 | MSigDB lists | GNF2_VAV1 | 37 | 12 | 17758 | 2588 |
HLA-B,RAC2,HLA-E,HLA-F,STAT6,INPP5D,PAK2,OSTF1,ARHGDIB,GRK6,HLA-C,PIK3CD |
| 4.783e-03 | -5.34 | BIOCARTA_PAR1_PATHWAY | MSigDB lists | BIOCARTA_PAR1_PATHWAY | 37 | 12 | 17758 | 2588 |
ARHGEF19,ARHGEF3,RHOA,ARHGEF11,ARHGEF7,PIK3R1,PIK3CA,MAP3K7,F2R,ARHGEF9,ARHGEF16,ARHGEF4 |
| 4.783e-03 | -5.34 | FRASOR_RESPONSE_TO_ESTRADIOL_UP | MSigDB lists | FRASOR_RESPONSE_TO_ESTRADIOL_UP | 37 | 12 | 17758 | 2588 |
OLFML2A,TOP2A,CYP1A1,PRSS23,AREG,RET,RAB31,EGR3,MYBL1,FOS,RASGRP1,CYP1B1 |
| 4.783e-03 | -5.34 | AMIT_EGF_RESPONSE_60_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_60_MCF10A | 37 | 12 | 17758 | 2588 |
MAGED2,SLC35D2,HES1,PTGS2,CTGF,CYR61,RND3,PLK2,CALD1,PTGER4,KLF7,IER3 |
| 4.787e-03 | -5.34 | establishment or maintenance of cell polarity | biological process | GO:0007163 | 146 | 34 | 16441 | 2455 |
FRMD4A,ARHGEF11,NDC80,MPP5,KIF2C,GPSM2,NCKAP1,SPDL1,LMNA,CKAP5,WEE1,ANK1,IGF1R,LLGL2,DLG1,PRKCI,DLG3,SPRY2,CENPA,SYNE2,EZR,SCRIB,ERBB2IP,ILK,NPHP3,ARF4,MAP1B,FRMD4B,RAB11FIP2,HTT,PTK7,SPINT2,ARF6,NDE1 |
| 4.793e-03 | -5.34 | embryonic organ development | biological process | GO:0048568 | 423 | 83 | 16441 | 2455 |
ACVR1,GRHL2,HSPG2,HOXB7,EPAS1,ST14,THRA,TP53,GATA3,PLAC1,OSR2,STIL,PDGFB,PDGFA,SETDB2,CTNNB1,ALDH1A3,DLG1,SMO,PLK4,TWIST1,DVL2,SPEF2,SOD1,AKT1,PRKRA,ABR,SOCS3,HS6ST1,PTK7,TBX1,TRAF3IP1,LRIG1,GAB1,E2F8,COBL,ARNT,PCSK5,CTHRC1,RUNX2,USH1C,TNRC6C,CDKN1C,SOX9,NES,TGFBR1,NCKAP1,HOXB2,SIX4,FZD6,GBX2,BMP2,E2F7,CYR61,GATA2,BMP7,MEGF8,TFAP2A,CITED2,NTN1,WNT3A,GFI1,TTPA,SPRY2,TMED2,MDFI,HES1,SCRIB,NPHP3,EGFR,GNAS,NCOA3,FGFR2,SPINT2,TBX18,NR4A3,PKD2,EFNA1,OSR1,FZD5,SHOX2,RARG,EGLN1 |
| 4.800e-03 | -5.34 | TSC22D4 (TSC22 domain family, member 4) | protein interactions | 81628 | 79 | 22 | 16036 | 2547 |
PRKAA2,RHOA,TSC22D3,FRMD6,PRKAA1,SAT1,CUL1,AES,ZMYND10,FXR2,PCBP1,CDK5R1,P4HA2,KPNA2,STK39,APIP,MAD2L1BP,MYLIP,PDPR,NRBP1,CRTAP,CKS2 |
| 4.803e-03 | -5.34 | YANG_BREAST_CANCER_ESR1_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_DN | 24 | 9 | 17758 | 2588 |
PLCH1,BTG3,PROM1,TRIM2,SLC9A6,CYB5R2,CDH3,LBR,ARHGEF9 |
| 4.803e-03 | -5.34 | ER_GOLGI_INTERMEDIATE_COMPARTMENT | MSigDB lists | ER_GOLGI_INTERMEDIATE_COMPARTMENT | 24 | 9 | 17758 | 2588 |
NUCB1,RGMB,P4HB,ERP44,NUCB2,PDIA6,TMED2,GOLGB1,KDELR1 |
| 4.803e-03 | -5.34 | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | MSigDB lists | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | 24 | 9 | 17758 | 2588 |
MAPKAPK2,RPS6KA2,RPS6KA1,MAPK11,DUSP4,MAPK7,ELK1,PPP2R5D,RPS6KA3 |
| 4.803e-03 | -5.34 | PROTEIN_KINASE_INHIBITOR_ACTIVITY | MSigDB lists | PROTEIN_KINASE_INHIBITOR_ACTIVITY | 24 | 9 | 17758 | 2588 |
CDKN2C,CDKN1C,DNAJC3,CDKN1B,HEXIM2,CDKN2D,PKIA,MAPK8IP1,SOCS3 |
| 4.803e-03 | -5.34 | REACTOME_DARPP_32_EVENTS | MSigDB lists | REACTOME_DARPP_32_EVENTS | 24 | 9 | 17758 | 2588 |
CALM2,CALM1,CALM3,PRKAR2B,PPP1CA,PDE4D,PRKACA,PPP2R5D,PRKAR1A |
| 4.803e-03 | -5.34 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_UP | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_UP | 24 | 9 | 17758 | 2588 |
DDB2,CSF1,DRAM1,PDK3,SESN1,NUP62CL,DENND2D,LEPR,FAS |
| 4.803e-03 | -5.34 | BIOCARTA_G2_PATHWAY | MSigDB lists | BIOCARTA_G2_PATHWAY | 24 | 9 | 17758 | 2588 |
PLK1,WEE1,RPS6KA1,TP53,CCNB1,MYT1,CDC25C,CDKN2D,CDK1 |
| 4.809e-03 | -5.34 | FZR1 (fizzy/cell division cycle 20 related 1) | protein interactions | 51343 | 103 | 27 | 16036 | 2547 |
PLK1,FOXM1,CKAP2,SPRTN,PTTG1,CDC20,EPHA4,TP53,CDCA3,CUL1,RACGAP1,AURKB,CCNB1,CDK1,RB1,CCNA2,HSF2,PTEN,DNM1L,UBE2D2,E2F1,NEK2,CKS1B,USP1,PIM1,UBE2C,ZC3HC1 |
| 4.810e-03 | -5.34 | phagocytic vesicle | cellular component | GO:0045335 | 80 | 21 | 17570 | 2579 |
LAMP1,UNC93B1,ANXA3,CLCN3,HLA-E,HLA-F,RAB23,RAB38,HLA-A,HLA-B,ATP6V0B,RAC2,OCRL,RAB11FIP1,RAB31,RAB20,ITGAV,HLA-C,SYK,ABCA1,ANXA11 |
| 4.829e-03 | -5.33 | EGFR interacts with phospholipase C-gamma | REACTOME pathways | R-HSA-212718 | 36 | 12 | 8202 | 1235 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,EGFR,PRKAR1A |
| 4.840e-03 | -5.33 | postsynaptic density | cellular component | GO:0014069 | 187 | 41 | 17570 | 2579 |
CPEB4,GRIK2,EPS8,EPHA4,LRP4,PJA2,PICK1,GRM5,NCS1,ADD3,ADORA1,ANKS1B,CABP1,DLG1,DNM2,MAP3K7,DLG3,CAMK2G,P2RX4,DLGAP1,DMTN,SHARPIN,GRIN1,CLSTN1,TANC1,CDK5R1,MAP1B,IL1R1,FYN,ATP1A1,HTT,MAP2,SIPA1L1,ITPR1,NETO2,ARRB1,GPER1,RGS14,NRGN,LZTS1,RUSC1 |
| 4.845e-03 | -5.33 | ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | MSigDB lists | ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | 155 | 35 | 17758 | 2588 |
BIN1,UGT8,CDKN1C,PPFIBP2,P2RX7,COL4A5,PPP2R3A,TMEM63A,SS18,KIF13B,LMO4,ABCA2,TMBIM6,WWP1,ERBB3,TIAM1,HSPA2,MX1,LAMP2,RASGRF1,PIK3R1,VAMP3,UBE2A,LITAF,KLK6,PRKCQ,RNF19B,FRMD4B,SCARB2,GPRC5B,FGFR2,CDK18,GLA,SLC31A2,COL16A1 |
| 4.857e-03 | -5.33 | upper_lobe | COSMIC cancer mutations | upper_lobe | 20 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 4.857e-03 | -5.33 | lung-middle_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-middle_lobe-carcinoid-endocrine_tumour-typical | 20 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 4.857e-03 | -5.33 | lung-middle_lobe-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-middle_lobe-carcinoid-endocrine_tumour-atypical | 20 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 4.857e-03 | -5.33 | lung-lower_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-lower_lobe-carcinoid-endocrine_tumour-typical | 20 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 4.857e-03 | -5.33 | lung-upper_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-upper_lobe-carcinoid-endocrine_tumour-typical | 20 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 4.857e-03 | -5.33 | central_nervous_system-brain-glioma-oligodendroglioma | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma | 20 | 8 | 17775 | 2585 |
CDKN2C,NF2,CTNNB1,PTEN,TP53,NOTCH2,IDH1,EGFR |
| 4.857e-03 | -5.33 | lung-bronchus-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-bronchus-carcinoid-endocrine_tumour-atypical | 20 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 4.857e-03 | -5.33 | skin-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-Merkel_cell_carcinoma | 20 | 8 | 17775 | 2585 |
NF2,CTNNB1,AKT1,PTEN,PIK3CA,TP53,FLT3,EGFR |
| 4.857e-03 | -5.33 | lung-bronchus-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-bronchus-carcinoid-endocrine_tumour-typical | 20 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 4.857e-03 | -5.33 | lower_lobe | COSMIC cancer mutations | lower_lobe | 20 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 4.859e-03 | -5.33 | EPN1 (epsin 1) | protein interactions | 29924 | 56 | 17 | 16036 | 2547 |
GAS2L1,REPS2,RALBP1,RNF11,PIK3R1,GTF3A,BCAR1,CDK1,EGFR,EPN3,AP1M2,SCNN1A,TADA2B,TFAP2A,ARRDC1,OCLN,EHD1 |
| 4.868e-03 | -5.33 | Toll-Like Receptors Cascades | REACTOME pathways | R-HSA-168898 | 140 | 33 | 8202 | 1235 |
SIGIRR,UNC93B1,HSP90B1,TAB3,RPS6KA1,CTSB,CUL1,RPS6KA2,IRAK1,PLCG2,DNM2,MAPK11,MAP3K7,LGMN,MAPK7,NFKB2,CNPY3,RIPK2,MAPKAPK3,PELI3,ELK1,DUSP4,FOS,CTSL,MAPKAPK2,PELI2,CTSV,NFKBIA,UBE2D2,NOD2,IRF7,PPP2R5D,RPS6KA3 |
| 4.871e-03 | -5.32 | REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM | MSigDB lists | REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM | 51 | 15 | 17758 | 2588 |
B3GALT6,HS6ST1,AGRN,HPSE,HSPG2,GUSB,GPC3,SDC4,GLB1,HS3ST3B1,SDC1,NDST3,EXT2,HS6ST3,GLCE |
| 4.871e-03 | -5.32 | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | MSigDB lists | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | 51 | 15 | 17758 | 2588 |
SOD1,TXN,SEC61B,IGFBP6,CDKN1C,CD63,NFKBIA,E2F1,CD70,FTH1,COX6C,GSTP1,S100A2,TP53I3,CAPN1 |
| 4.882e-03 | -5.32 | recycling endosome | cellular component | GO:0055037 | 127 | 30 | 17570 | 2579 |
MYO5B,AMOTL2,PACSIN2,ATP9A,NDRG1,RNF11,PANK1,VAMP3,SLC11A2,FAM109A,MICALL2,SLC9A7,OPTN,USP6,LDLRAP1,RAB11FIP2,KCNK1,SLC9A6,RAP2C,RAB11FIP1,SGK3,TUBG1,SORL1,GPER1,ARF6,SLC31A2,GPR161,MYO5A,ABCG1,EHD1 |
| 4.888e-03 | -5.32 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP | 194 | 42 | 17758 | 2588 |
LTBP1,CDS2,PAPSS2,NQO1,AGRN,ATP9A,TRAF2,PPFIBP2,STRN4,FAM134A,HES2,SPR,SPSB1,PHF1,BMP2K,SGPL1,CALR,AKIRIN1,ST5,RPS6KA2,ADORA1,CA2,CNTRL,CRY2,ERCC2,NR2C1,TRAK2,MAP3K3,MX1,TIMP2,COL6A2,CTNNAL1,NFE2L1,BSDC1,NFIX,NCOA3,RPL12,NR1D2,PRDM5,CANT1,USF2,ABCG1 |
| 4.888e-03 | -5.32 | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | 194 | 42 | 17758 | 2588 |
TXN,IL15RA,SERPINE2,TUBB4B,CTDSPL,COL4A5,TGOLN2,BCL2L1,DDR1,PDXDC1,DNAJB9,CD46,TFAP4,ADD3,CTNNB1,NECAB3,FAM102A,IL17RA,MDFIC,ACSL4,WBP4,IL10RB,CKAP4,KDELR1,DOCK4,PGM1,SH3BGRL,DCHS1,UTRN,PRRC1,CCNF,CD40,PDHX,HNRNPH2,SPINT2,UBE2D2,OSMR,ATP1B3,MAP3K5,TRAF5,SRSF9,PCSK5 |
| 4.888e-03 | -5.32 | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDM_UP | 194 | 42 | 17758 | 2588 |
TTC39B,NFKBIE,TRIP10,NDRG1,RASA2,ARFGEF1,NOTUM,COMMD5,LGALS3BP,SPP1,FLII,RRBP1,KLF3,SGK3,AOX1,H2AFY,TRIM21,CDKN1B,NPTXR,ETHE1,TFG,CTDSP2,SMAGP,PMPCB,PTPN18,PLSCR1,NR3C1,STAT4,ZBTB7B,SPTLC2,SP4,GINS4,NAAA,FYN,NR1D2,WFS1,MAL2,GLA,SERPINB1,TOB1,CBX4,STARD3NL |
| 4.888e-03 | -5.32 | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_UP | 194 | 42 | 17758 | 2588 |
KLF2,PSME2,PNPLA2,TAP1,DGKA,GATA3,PSME1,ISYNA1,MAP1LC3B,GNB2,OXCT1,CAPG,CD9,CDKN1B,ZNF692,USP38,RNF26,CTDSP2,EPHX1,SEPT6,PLEKHO1,FHL2,SPATA13,LITAF,TCF7,ESYT1,TAPBP,CD8A,PEX5,CASP7,NAT1,FAM3C,PRKCDBP,HDAC1,PPP2R3C,GLB1,PLXND1,CMPK2,LTA4H,MAD2L1BP,IFIH1,NRBP1 |
| 4.888e-03 | -5.32 | GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP | 194 | 42 | 17758 | 2588 |
GRN,LAMP1,ANXA3,SPRED1,IQGAP1,CUL4B,FAM102B,TRAPPC8,ARHGEF40,FAM46C,VPS26A,ATG4A,AKIRIN1,SNX13,SS18,RGS12,IGF1R,CTNNB1,DNAH6,KCNN4,PAK2,SRP54,TAX1BP3,SLAIN2,KLF9,CTTN,ENPP4,LPGAT1,PYGL,MCFD2,ULK2,CRISPLD2,CD83,NIN,AP1AR,HTT,KBTBD2,SLC25A40,LRIG1,ZMIZ1,RTN3,CXorf56 |
| 4.888e-03 | -5.32 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 194 | 42 | 17758 | 2588 |
CD99,TXN,CUL1,TXNDC9,KIF2C,STIL,PSIP1,KCTD9,VPS26A,PCNA,CCNA2,PPP4R1,PRC1,MSH2,PLK4,GOT1,USP1,RFX5,FAIM,SCN3A,WBP5,TDP1,PCCB,HES1,RHOA,ZWINT,TIMP2,MPP1,LYRM1,CDC20,MYBL2,GTF2A2,SPAG1,RHEB,IDE,CDCA4,ETS2,GDE1,PGRMC1,CENPE,ATP6V1C1,SRSF9 |
| 4.888e-03 | -5.32 | GSE27786_CD4_TCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NKTCELL_DN | 194 | 42 | 17758 | 2588 |
UNC93B1,GALK1,ACVR1,ARAP3,DNAJC3,DCAF7,PNPLA2,ARMC7,TRAPPC8,BAIAP3,IFT27,SRPX2,GRM5,SLC25A36,NUP210,FAM46A,EFR3A,CENPJ,OSBPL3,GALNS,RRBP1,H2AFY,VAT1,WWP1,ASH2L,OSTF1,ARL4D,SPRY2,SLC45A3,NAGA,ARAP2,LAP3,SLC35C1,GNAS,TNS4,MYPOP,DDOST,C1orf21,LRRK1,HMGA1,GEM,ARPC2 |
| 4.888e-03 | -5.32 | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDM_DN | 194 | 42 | 17758 | 2588 |
ARHGEF3,PARP14,KLHL13,DNAJC3,RASA2,SOD2,OSGIN2,PRSS22,TNFSF9,RPS6KA2,SPIN4,CD70,TSPAN33,B3GNT2,MMD,PLSCR1,PIK3R1,RNF11,CYS1,PRKCQ,RNF19B,NPDC1,MAP3K6,COL12A1,EDNRA,BCL10,IRX3,IRS2,PTGS2,PLCG1,ETS2,SYT7,NGFRAP1,WIPI1,MMP17,TBX1,ICOSLG,TTC39C,TRAF5,CBX4,PROM2,EHD1 |
| 4.893e-03 | -5.32 | frontotemporal | COSMIC cancer mutations | frontotemporal | 9 | 5 | 17775 | 2585 |
CDKN2C,CTNNB1,IDH1,PTEN,TP53 |
| 4.901e-03 | -5.32 | positive regulation of biosynthetic process | biological process | GO:0009891 | 1796 | 306 | 16441 | 2455 |
ACVR1,TRIM24,LGR4,TRIM5,DNAJC3,HEXB,RET,GATA3,MORF4L2,CAMK1D,TP73,NPM2,CALM2,HELZ2,CTGF,IL31RA,FOSB,DNM2,IRF2,NEK4,SMARCA2,TNIP1,TFAP2C,AURKB,LDB2,SAV1,POR,ARF4,AHRR,MID1IP1,AREG,TBX1,NOD2,HDAC1,RNASEL,HSPB1,TRAF5,F2RL1,E2F8,HOXC13,DDX58,KLF2,CDKN1C,ITGA6,SOX9,PRKAA1,PSIP1,LMNA,MECOM,ELF3,TFAP4,CALR,CYR61,NEK2,MYDGF,MAPK7,NUP85,GPR161,SALL4,STAT4,CALM1,PYM1,FHL2,MYBL2,CALCRL,ELK1,ILK,TP53INP2,KDM3A,NFIB,PLIN5,NCOA3,SERTAD2,ETS2,SETD3,PIAS2,NR4A2,RPS6KA3,TMEM173,IRF1,ARMCX3,GRHL2,THRA,RPS6KA1,CCNA2,CDH1,SP100,DAB2IP,ETV4,MED30,PSRC1,RIPK2,FZD4,FOXJ2,PRKCQ,PXYLP1,PYGO1,GTF2A2,EBF2,FZD7,NFIX,IRS2,WFS1,WWTR1,STAT1,KLF5,NRG1,ARNT,ATMIN,NKX3-1,CKAP2,TRAF2,PBX3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,E2F7,IRAK1,PTEN,MCF2L,CST3,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,PDGFC,CASK,PLSCR1,BCL9,TEF,PIK3R1,EIF5A2,GRIN1,YES1,FOS,ABLIM2,TXK,GPLD1,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,ACVRL1,NR1D2,NR4A3,GPER1,HMGA1,FZD5,OSR1,CD81,USF2,SHOX2,FOXA1,USP16,RGMA,CCNC,EPAS1,AGRN,ARFGEF1,HDAC6,PDGFB,TFAP2E,EPCAM,HSF2,PCNA,CTNNB1,GRHL1,NPNT,PSMC2,ELF5,PASK,MITF,ASH2L,ARNT2,MYBL1,ZNF462,THRB,PCGF5,TRIM8,CITED4,ASXL1,NFE2L1,EAF2,VCP,EDNRA,SEC14L2,MDK,KLF12,MAFF,PSMC1,NR2C2,RUNX2,PPP1R12A,ETV5,CALM3,BMP2,RB1,IGF1R,GATA2,PRKCI,SUCO,EBF4,MDFIC,WNT3A,ELK3,RGMB,EGFR,GNAS,MAPKAPK2,ONECUT1,INSR,PLPP3,NFKBIA,NLRC5,RARG,RAD21,DRD1,KLF7,PAX6,SORBS1,UPF3B,IL15,FOXM1,TP53,ERBB2,CCNL1,OSR2,LPIN3,PDGFA,SS18,LMO4,SMO,CDH3,TWIST1,ZBTB49,NOTCH3,NFKB2,F2R,DVL2,UPF3A,CTH,CHP1,SOAT1,SIRT1,CLCN3,TIMP2,AKT1,TCEB2,SERTAD3,CD40,JADE1,HSF4,PTGS2,RBL1,STAT6,IRF7,AKNA,ABCA1,CNEP1R1,GLIS3,ANXA3,PINK1,TAB3,ARHGEF11,GNAL,HMGN3,TGFBR1,PARM1,GBX2,IRF2BPL,TOP2A,BMP7,TOX2,GTF2F2,TFAP2A,BRD7,TRIM21,SYK,NFE2L3,P2RX4,HES1,RHOA,DCAF6,WNT10B,HMGN5,NR3C1,NR4A1,RGCC,PPARA,MAML2,RUNX3,MPV17L2,BCL10,DDAH1,E2F1,ARRB1,PKD2,ZMIZ1,SOX8,AHR,ABCG1 |
| 4.905e-03 | -5.32 | microtubule bundle formation | biological process | GO:0001578 | 69 | 19 | 16441 | 2455 |
PLK1,GAS2L1,CFAP74,SPEF2,PSRC1,KIF20A,CAPN6,AK7,CFAP46,ZMYND10,BBS2,SPAG1,MAP1B,LRRC6,MAP2,TTLL1,DNAI1,CHP1,DNAAF3 |
| 4.921e-03 | -5.31 | WWE | prosite domains | PS50918 | 12 | 6 | 11866 | 1802 |
PARP12,PARP14,TIPARP,RNF146,DDHD2,DTX4 |
| 4.922e-03 | -5.31 | REACTOME_HS_GAG_DEGRADATION | MSigDB lists | REACTOME_HS_GAG_DEGRADATION | 20 | 8 | 17758 | 2588 |
AGRN,HPSE,HSPG2,GUSB,GPC3,SDC4,GLB1,SDC1 |
| 4.922e-03 | -5.31 | NIELSEN_LEIOMYOSARCOMA_CNN1_DN | MSigDB lists | NIELSEN_LEIOMYOSARCOMA_CNN1_DN | 20 | 8 | 17758 | 2588 |
ADD3,BMP7,FRAS1,ETV5,UACA,LOXL2,SPRY2,SOCS3 |
| 4.922e-03 | -5.31 | V$MAZR_01 | MSigDB lists | V$MAZR_01 | 211 | 45 | 17758 | 2588 |
CCDC24,SLC2A4,PAX6,FAF2,HOXB7,TRIP10,PPM1J,ZCCHC24,FXYD3,ITGA6,ETV5,NOTCH2,APBA1,GNB2,SLC9A7,IRF2BPL,CTNNBIP1,VASP,TNPO2,PIM1,SULT2B1,NCOA2,CAMK2G,ZNF462,KREMEN2,PHLDB3,FOXJ2,FXR2,ABR,MAGED2,PTPRF,CAMK2N2,RBL1,H1F0,CORO1C,RAP2C,NXPH4,FAM117A,GRIN2D,EFNA1,HMGA1,RTN3,AHR,FOXA1,DMPK |
| 4.931e-03 | -5.31 | regulation of nuclear division | biological process | GO:0051783 | 157 | 36 | 16441 | 2455 |
DLGAP5,CIT,PTTG1,PDGFB,NPM2,CALR,RB1,RPS6KA2,IGF1R,PTEN,BMP7,NEK2,MSH2,BUB1,KNTC1,PLK1,CDC20,RGCC,VPS4B,NUSAP1,KIF20B,PKMYT1,ANLN,KIF11,BORA,CDC25C,INSR,FGFR2,CDCA5,AURKA,CHMP4B,CENPE,UBE2C,MAD2L1BP,ESPL1,PRKAR1A |
| 4.939e-03 | -5.31 | ST_JAK_STAT_PATHWAY | MSigDB lists | ST_JAK_STAT_PATHWAY | 9 | 5 | 17758 | 2588 |
SOAT1,PIAS3,JAK1,PTPRU,JAK3 |
| 4.939e-03 | -5.31 | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP | MSigDB lists | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP | 9 | 5 | 17758 | 2588 |
GDF15,CYFIP2,SESN1,TP53I3,SULF2 |
| 4.939e-03 | -5.31 | OHASHI_AURKB_TARGETS | MSigDB lists | OHASHI_AURKB_TARGETS | 9 | 5 | 17758 | 2588 |
RACGAP1,KIF2C,AURKB,CENPA,CDCA8 |
| 4.958e-03 | -5.31 | single organismal cell-cell adhesion | biological process | GO:0016337 | 447 | 87 | 16441 | 2455 |
MYL9,IL15,LFNG,CERCAM,RET,TP53,PKP2,P2RX7,GATA3,FLT3,NOV,CDH1,CTNNB1,NPNT,DLG1,CDH3,PIK3CD,CYP1B1,CAMSAP3,RIPK2,TNIP1,PTPRU,PTGER4,EZR,MYL12A,LCP1,FZD7,FYN,DDOST,STAT6,CTNND1,ANXA9,RPL22,F2RL1,HSPB1,FBLIM1,RUNX2,BVES,HLA-E,SOX9,BTN3A1,CBLL1,JAG2,SRPX2,IL18R1,ICAM1,ITGA2B,RAC2,CYR61,BMP7,ICAM5,KIF13B,CTPS1,BAX,ARVCF,WNT3A,NTN1,RAG1,SYK,GCNT1,ADAM17,RHOA,PODXL2,MICB,RC3H2,PLEKHA7,SCRIB,VEZT,CYFIP2,FNDC3A,ILK,EGFR,CDK5R1,FAS,TXK,GNAS,CD8A,TSC1,COL13A1,SEMA4D,PLPP3,ITGA7,ITGAV,ICOSLG,FZD5,L1CAM,IRF1 |
| 4.959e-03 | -5.31 | REACTOME_ACTIVATED_TLR4_SIGNALLING | MSigDB lists | REACTOME_ACTIVATED_TLR4_SIGNALLING | 91 | 23 | 17758 | 2588 |
SIGIRR,RIPK2,TAB3,MAPKAPK3,RPS6KA1,PELI3,DUSP4,ELK1,FOS,CDK1,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,IRF7,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 4.960e-03 | -5.31 | KEGG_AXON_GUIDANCE | MSigDB lists | KEGG_AXON_GUIDANCE | 128 | 30 | 17758 | 2588 |
DPYSL5,SEMA6B,RHOA,EPHA4,PLXNA1,EPHA1,EFNB1,NFAT5,ABLIM2,RASA1,RND1,PAK6,RAC2,FYN,SEMA4D,DPYSL2,RGS3,LIMK1,PAK2,EFNA5,NTN4,EFNA1,EPHB4,SEMA3G,UNC5B,NTN1,SEMA3A,L1CAM,SEMA3B,NGEF |
| 4.960e-03 | -5.31 | chr1q32 | MSigDB lists | chr1q32 | 128 | 30 | 17758 | 2588 |
ELK4,TMCC2,CD55,DYRK3,PLEKHA6,ASCL5,ZC3H11A,SERTAD4,CR2,NENF,GOLT1A,RNPEP,C1orf116,ELF3,SOX13,MAPKAPK2,CD46,ADORA1,PPP2R5A,UBE2T,LRRN2,KIF14,NEK2,YOD1,ADIPOR1,PIK3C2B,LEMD1,TRAF5,SLC45A3,DDX59 |
| 4.978e-03 | -5.30 | Information processing speed(PMID:21130836) | GWAS genes | Information processing speed(PMID:21130836) | 9 | 5 | 2389 | 350 |
ATRNL1,KCTD2,MYRIP,TMEM245,FAM110C |
| 4.983e-03 | -5.30 | epithelium migration | biological process | GO:0090132 | 74 | 20 | 16441 | 2455 |
GRHL2,NR4A1,TGFBR1,LOXL2,EGR3,PKN1,ANLN,EMP2,S100A2,CORO1B,GPLD1,NOV,PTEN,SCG2,PIK3CA,STAT1,EPHB4,PLXND1,ARSB,CYP1B1 |
| 4.983e-03 | -5.30 | collagen catabolic process | biological process | GO:0030574 | 74 | 20 | 16441 | 2455 |
COL9A3,ADAMTS2,MRC2,ADAM17,COL6A2,CTSB,FURIN,COL18A1,KLK6,COL7A1,COL4A5,COL12A1,MMP15,CTSL,COL13A1,COL6A1,ADAM15,ADAMTS14,CTSD,COL16A1 |
| 4.984e-03 | -5.30 | I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | MSigDB lists | I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | 112 | 27 | 17758 | 2588 |
MAP3K3,CXXC5,RHOA,RIPK2,TRAF2,LITAF,CD40,SLC20A1,CARD10,PRDX4,BCL10,CARD8,IRAK1,TSPAN6,PLK2,SECTM1,STAT1,NOD2,ZDHHC13,CANT1,SLC44A2,MAP3K7,TFG,F2R,TRAF5,NDFIP1,EEF1D |
| 4.987e-03 | -5.30 | GSE3982_MAST_CELL_VS_MAC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_DN | 183 | 40 | 17758 | 2588 |
EPAS1,MPZL1,IL13RA1,TGFBR1,IL27RA,BLCAP,TEX2,FAM198B,BCL2L1,NANS,NFAT5,PPP2R3A,PLS3,EPCAM,SNX13,ITGA3,CDK16,GALNS,MITF,AOX1,TNFRSF12A,RP2,ETHE1,NAGPA,BAG4,GUSB,RC3H2,AK4,DNAJB14,ALCAM,GINS4,RHEB,OPTN,ATP1A1,RBL1,STAT1,ZDHHC7,CLIP4,KPNA2,PDXK |
| 4.987e-03 | -5.30 | GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP | 183 | 40 | 17758 | 2588 |
BIN1,PLEKHG3,LZTFL1,IGFBP6,TSC22D3,ATP2C2,GATA3,IL18,TDRKH,CCNL1,PHF1,PARM1,MARCH8,RPL39,ALG13,HLA-C,MPHOSPH9,SCYL3,CTDSP2,CRTAP,SMAGP,MAP3K3,TGIF1,TBC1D8B,NR3C1,SYNE2,CXorf57,CLSTN1,TCF7,KIAA1109,RASA1,MMP15,IRS2,HLA-B,TSC1,INPP4B,RYK,NR3C2,CBX7,PHC1 |
| 4.990e-03 | -5.30 | MHC_I_a | interpro domains | IPR027648 | 9 | 5 | 18293 | 2672 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 4.990e-03 | -5.30 | Metal-dep_hydrolase_composite | interpro domains | IPR011059 | 9 | 5 | 18293 | 2672 |
DPYSL5,DPYSL4,AMDHD1,DPYSL2,DPYSL3 |
| 4.991e-03 | -5.30 | regulation of cell aging | biological process | GO:0090342 | 32 | 11 | 16441 | 2455 |
NEK4,SIRT1,FOXM1,NUAK1,PTEN,BCL6,TP53,TWIST1,HMGA1,VASH1,LMNA |
| 4.991e-03 | -5.30 | osteoclast differentiation | biological process | GO:0030316 | 32 | 11 | 16441 | 2455 |
CD109,CTNNB1,FAM20C,OSTM1,CSF1,GPC3,MITF,GLO1,LRRK1,SNX10,FARP2 |
| 4.996e-03 | -5.30 | regulation of protein complex disassembly | biological process | GO:0043244 | 89 | 23 | 16441 | 2455 |
GAS2L1,ADD1,CKAP2,DMTN,DSTN,EPS8,EIF5A2,NES,AURKB,CCNB1,HDAC6,APC2,SPTB,PLEKHH2,SWAP70,MID1IP1,CAPG,TRIOBP,AURKA,TMOD2,SPTBN5,SHROOM2,F2RL1 |
| 4.996e-03 | -5.30 | SH2D2A (SH2 domain containing 2A) | protein interactions | 9047 | 15 | 7 | 16036 | 2547 |
ERBB2,PLCG1,MAPK7,SYK,EGFR,VCP,TXK |
| 4.996e-03 | -5.30 | TRPC4 (transient receptor potential cation channel, subfamily C, member 4) | protein interactions | 7223 | 15 | 7 | 16036 | 2547 |
MX1,TRPC1,ITPR2,ITPR3,TRPC3,ITCH,ITPR1 |
| 4.996e-03 | -5.30 | LRIG1 (leucine-rich repeats and immunoglobulin-like domains 1) | protein interactions | 26018 | 15 | 7 | 16036 | 2547 |
CANT1,ERBB2,ERBB3,SCARA3,CBL,EGFR,VCP |
| 4.996e-03 | -5.30 | MYL12B (myosin light chain 12B) | protein interactions | 103910 | 15 | 7 | 16036 | 2547 |
CUL1,ARRB1,LGALS3,MYLIP,HSPB1,PNKD,DAPK1 |
| 4.996e-03 | -5.30 | SLC12A4 (solute carrier family 12 (potassium/chloride transporter), member 4) | protein interactions | 6560 | 15 | 7 | 16036 | 2547 |
CD55,LGALS3,FAM189A2,TMEM43,LGALS8,LYPD6,FLOT1 |
| 4.996e-03 | -5.30 | SOCS7 (suppressor of cytokine signaling 7) | protein interactions | 30837 | 15 | 7 | 16036 | 2547 |
IRS2,SORBS3,PLCG1,TUBB4B,SEPT6,EGFR,PIK3R1 |
| 4.996e-03 | -5.30 | PHKB (phosphorylase kinase, beta) | protein interactions | 5257 | 15 | 7 | 16036 | 2547 |
AURKB,DOK4,CORO1C,CALM1,DCP2,CORO1B,TP53 |
| 5.008e-03 | -5.30 | protein kinase A binding | molecular function | GO:0051018 | 41 | 13 | 16491 | 2452 |
DACT1,ACBD3,SOX9,ARFGEF1,AKAP17A,EZR,PRKAR2B,AKAP3,PJA2,PRKACA,MYRIP,PKIA,PRKAR1A |
| 5.009e-03 | -5.30 | PSMD6 (proteasome 26S subunit, non-ATPase 6) | protein interactions | 9861 | 84 | 23 | 16036 | 2547 |
PSMB4,PSME2,AMFR,RNF11,TP53,PSMD7,PSMD10,PSME1,UBAC1,ATP1B1,MCFD2,ZFAND5,PSMA4,PLS3,RAD23A,CCDC92,PSMD1,PSMD3,PSMC2,CCDC74B,ATP1B3,PSMC1,PSMA5 |
| 5.009e-03 | -5.30 | cellular catabolic process | biological process | GO:0044248 | 1338 | 233 | 16441 | 2455 |
CASP3,GAA,FAF2,AASS,CRYM,CPT2,CNOT8,PNPLA2,DNAJC3,CUL4B,HEXB,MCCC1,FBXO2,CUL1,UBE2Z,PSME1,CCNB1,OAT,HDAC6,ECI1,CALM2,MAGOHB,TYMP,CYP1A1,PSMD1,ENTPD4,ZFP36,CYP2S1,PSMC2,PPP1CA,TINAGL1,ACOX2,APOBEC3G,ERAP2,CYP1B1,PLK1,FBXL16,SPATA18,ITCH,USP18,RNF11,CDA,BNIP3L,RNF165,CCBL2,MGAM,AGO4,AURKB,CCNF,RNF19B,PNKD,CYP4F3,CDK1,POR,VCP,TRIM9,ENPP1,PLCG1,NEIL1,HPSE,GLA,PSMC1,CAPN1,ALDH6A1,CYP2J2,DNAJB2,PSMD7,ASL,CALM3,ZNRF3,GNS,RPL39,FBXO7,BDH1,NEK2,FBXL14,PCYOX1,AHCY,USP1,USP38,STT3B,ACAD8,ZRANB1,MYLIP,GAD1,PHKG2,MCCC2,PSMA5,EPHX1,CYP26B1,UFD1L,PRODH,USP31,CALM1,PYM1,FBXO8,PYGL,PDE5A,TP53INP2,PSMA4,FBXO10,AMDHD1,DCP2,PDE11A,NUDT16,NT5C2,H1F0,FAAH,PAPD5,AURKA,YOD1,CTSA,PLD1,RNF146,XDH,USP43,FBXW5,PLA2G4A,UPF3B,PSME2,PTTG1,MVB12B,LPIN3,PATL2,PRKACA,NUDT12,CYP39A1,CYP26A1,RAD23A,CYP4F11,KIF14,PLCG2,FABP6,DAB2IP,GOT1,ECE1,RNASEH2A,PDE4D,PHKA2,ETHE1,LGMN,NAGA,GM2A,UPF3A,CTH,SIRT1,ENPP4,SEC61B,ERLEC1,CDC20,VPS4B,CBL,ZMPSTE24,DNAJC10,DUOX1,ALDH3B1,ALDH5A1,IDE,ACAD10,ABHD12,PSMD3,WFS1,WWTR1,PEX2,MAOA,PPP1CB,CHMP4B,PRIMA1,CYP2U1,RPL22,AREL1,LTA4H,PINK1,HSP90B1,GCAT,CIT,JKAMP,CTSB,HAL,BLVRB,ERI2,PSMD10,CTSZ,APOBEC3H,PLD2,FBXO6,DNAJB9,WWP2,SGPL1,CAPN2,OXCT1,RNF128,CTSC,MGAT1,GALNS,UBE2J1,ECI2,WWP1,ALDH7A1,HMGCL,ABCD1,CNOT6L,FAH,PCCB,PGM1,SHMT1,PSMB4,AMFR,NUB1,UBE2A,FBXO9,BLVRA,RNPEP,USP6,CNOT2,CTSL,DDAH1,RPL12,ACADSB,PRDX3,CTSV,PLA2G15,UBE2D2,ARRB1,ERAP1,GLB1,ACADM,ARSB,NDFIP1,UBE2C,ACOT7,USP16,DIS3L |
| 5.022e-03 | -5.29 | dendrite development | biological process | GO:0016358 | 84 | 22 | 16441 | 2455 |
FARP1,CELSR2,FMN1,CIT,LRP4,SLC11A2,ARF4,MAP1B,FYN,IGSF9,PTEN,MAP2,BMP7,SLC9A6,DACT1,MATN2,PAK2,PRKG1,ACSL4,BTBD3,SEMA3A,KLF7 |
| 5.061e-03 | -5.29 | V$TCF11MAFG_01 | MSigDB lists | V$TCF11MAFG_01 | 200 | 43 | 17758 | 2588 |
UNKL,SPRED1,MRC2,LRRFIP2,ARHGEF11,GRIK2,BLVRB,IRX4,CALM3,IL13RA1,GRK6,PRR7,PDGFB,BEX2,VPS26A,PLS3,CALM2,ST5,WDR44,NECAB3,LMO4,MITF,RIMS2,PSMA5,DNAI1,RASGRF1,UFD1L,CALM1,CBX6,ATP1B1,SNX12,SFXN5,VCP,TBC1D17,POPDC3,LIMK1,FIBCD1,PGRMC1,SERPINB5,DRP2,NRGN,RTN3,JARID2 |
| 5.063e-03 | -5.29 | BMI1_DN_MEL18_DN.V1_UP | MSigDB lists | BMI1_DN_MEL18_DN.V1_UP | 139 | 32 | 17758 | 2588 |
ANXA3,RUSC2,ARL4C,TNFSF9,NRP2,HTR1D,CCND1,WEE1,ITGA3,ITGB8,FAM189A1,KCNN4,FJX1,TMEM51,DUSP10,PIM1,PLAUR,PLEKHO1,NKAIN1,COL7A1,LHFPL2,LCP1,CRISPLD2,ATP13A2,TIMP3,COL13A1,CSF1,PIEZO1,ABCA1,COL16A1,EHD1,KLF7 |
| 5.064e-03 | -5.29 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043281 | 212 | 46 | 16441 | 2455 |
CASP3,NKX3-1,RPS6KA1,DAP,TRAF2,SERPINB9,RET,XIAP,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,PAK2,DAPK1,BAX,CDKN1B,FNIP1,RAG1,EGLN3,WNT3A,CDKN2D,F2R,SIRT1,RHOA,AKT1,ACVR1C,PLAUR,CASP9,SLC11A2,BCL2L13,POR,VCP,FAS,BCL10,CASP7,KIAA0141,PRDX3,NGFRAP1,ARRB1,GPER1,MAP3K5,IFI6,RPS6KA3,XDH |
| 5.068e-03 | -5.28 | JOHNSTONE_PARVB_TARGETS_1_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_1_DN | 56 | 16 | 17758 | 2588 |
CDKN2AIP,MCTP1,SCOC,CTSB,PTGER4,DNAJB14,DSE,STEAP1,ATP10D,PDGFA,ITGB8,SHC3,LIMCH1,RELL1,SLC12A2,LIFR |
| 5.068e-03 | -5.28 | MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | 56 | 16 | 17758 | 2588 |
SOAT1,ALDH2,CD40,LCP1,CD83,GNS,TAPBP,BTG1,SEMA4D,CD22,AIM1,CAPG,ITGAV,RGS14,SERPINB1,CAPN1 |
| 5.068e-03 | -5.28 | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | MSigDB lists | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | 56 | 16 | 17758 | 2588 |
PLK1,SERPINE2,CD63,PBK,CDC20,FOS,CDK1,NIN,TOP2A,CCND1,SPP1,PCNA,DBI,CD9,TAGLN2,SULF2 |
| 5.068e-03 | -5.28 | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | MSigDB lists | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | 56 | 16 | 17758 | 2588 |
CXXC5,EPAS1,FHL2,HTATIP2,IL13RA1,S100A2,EPCAM,SPP1,MID1IP1,SPINT2,STAT1,NXPH4,MAOA,ARMCX6,ABCA1,LZTS1 |
| 5.069e-03 | -5.28 | human chr11p11.2 | chromosome location | human chr11p11.2 | 62 | 14 | 26250 | 2805 |
MDK,DDB2,PTPRJ,CD82,LRP4,TSPAN18,MADD,GYLTL1B,SLC35C1,CRY2,SYT13,TP53I11,MAPK8IP1,CKAP5 |
| 5.085e-03 | -5.28 | inner ear development | biological process | GO:0048839 | 179 | 40 | 16441 | 2455 |
CTHRC1,USH1C,SOX9,CCM2,SDC4,MCOLN3,SLC25A27,GATA3,JAG2,PLPPR4,TMC1,SLC9A3R2,SIX4,FZD6,GBX2,PLS3,BMP2,GATA2,ALDH1A3,TFAP2A,ATP8B1,CDKN1B,WNT3A,NTN1,GFI1,SPRY2,DVL2,HES1,SOD1,DCHS1,SCRIB,ABR,MAPKAPK2,FAT4,FGFR2,TBX1,PTK7,TBX18,LRIG1,NR4A3 |
| 5.085e-03 | -5.28 | positive regulation of cellular protein catabolic process | biological process | GO:1903364 | 179 | 40 | 16441 | 2455 |
DLGAP5,DNAJB2,PSME2,PSMD7,CUL1,PSMD10,PSME1,TRIB2,CCNB1,BCAP31,RB1,PSMD1,RNF128,CTSC,PTEN,PSMC2,DAB2IP,OSBPL7,PSMA5,SOCS5,PLK1,VPS11,AKT1,PSMB4,GCLC,NUB1,CDC20,PRICKLE1,EZR,RNF19B,PSMA4,CDK1,VCP,PSMD3,PLK2,AURKA,CD81,UBE2C,PSMC1,ESPL1 |
| 5.099e-03 | -5.28 | Colorectal cancer | KEGG pathways | ko05210 | 62 | 18 | 6908 | 1076 |
CASP3,RHOA,AKT1,PIK3R1,CASP9,TP53,TGFBR1,TCF7,FOS,APC2,CCND1,RAC2,CTNNB1,PIK3CA,MSH2,BAX,PIK3CD,MSH6 |
| 5.099e-03 | -5.28 | Colorectal cancer | KEGG pathways | hsa05210 | 62 | 18 | 6908 | 1076 |
CASP3,RHOA,AKT1,PIK3R1,CASP9,TP53,TGFBR1,TCF7,FOS,APC2,CCND1,RAC2,CTNNB1,PIK3CA,MSH2,BAX,PIK3CD,MSH6 |
| 5.099e-03 | -5.28 | platelet dense tubular network membrane | cellular component | GO:0031095 | 9 | 5 | 17570 | 2579 |
ITPR2,ITPR3,DMTN,ITPR1,EHD1 |
| 5.104e-03 | -5.28 | ADENYL_RIBONUCLEOTIDE_BINDING | MSigDB lists | ADENYL_RIBONUCLEOTIDE_BINDING | 161 | 36 | 17758 | 2588 |
GALK1,TNK1,ACVR1,DYRK3,PINK1,PEX6,ABCG2,TP53,TGFBR1,ABCD4,DAPK2,CDKL5,PRKCI,ABCA2,MSH2,DAPK1,PIM1,MSH6,SMC4,ABCC1,SEPHS1,MARK1,GCLC,PIF1,MAP3K6,STK17B,DGKE,STK17A,ACVRL1,STK38,ATP7B,PPP2R4,ABCB1,MAP3K5,DMPK,ABCG1 |
| 5.108e-03 | -5.28 | NEGATIVE_REGULATION_OF_PROGRAMMED_CELL_DEATH | MSigDB lists | NEGATIVE_REGULATION_OF_PROGRAMMED_CELL_DEATH | 150 | 34 | 17758 | 2588 |
CASP3,ACVR1,HSP90B1,SERPINB9,XIAP,NOTCH2,BCL2L1,GSTP1,BARD1,IER3,IGF1R,BAX,TNFRSF18,PIM1,CDKN2D,TMX1,SOD1,BAG4,GCLC,BNIP3L,HTATIP2,GLO1,CDK1,RASA1,BCL10,SOCS3,FAS,SCG2,SEMA4D,HDAC1,HSPB1,HIPK3,IFI6,CBX4 |
| 5.110e-03 | -5.28 | ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase) | protein interactions | 471 | 70 | 20 | 16036 | 2547 |
PGM1,SHMT1,TXN,GLO1,SPR,EGFR,ELF3,CAPN2,INSR,JAK1,OXCT1,DNM1L,STK26,PAPSS1,AHCY,PLIN3,HSPB1,CTBP1,ISOC1,CTH |
| 5.129e-03 | -5.27 | HLA-DRA (major histocompatibility complex, class II, DR alpha) | protein interactions | 3122 | 43 | 14 | 16036 | 2547 |
MAN2A2,MBP,TCTN2,STIM1,CD63,CD82,IMPAD1,LRIG1,NETO2,EPHB4,ATP1B1,PLXNA1,PKM,ANXA11 |
| 5.163e-03 | -5.27 | protein secretion | biological process | GO:0009306 | 136 | 32 | 16441 | 2455 |
BTN3A1,GATA3,UBE2Q1,ERP29,PDIA4,SVBP,RAB15,NECAB3,CPLX1,STEAP3,ARL4D,RAB27B,S100A13,CAMK2G,MYO5A,RIMS2,RAB3B,DMTN,BTN3A2,RNF19B,OPTN,GNAS,RAB11FIP2,SCG2,HTT,GNPTAB,NOD2,ARFGAP3,LTBP2,F2RL1,ABCA1,PCSK5 |
| 5.178e-03 | -5.26 | WANG_HCP_PROSTATE_CANCER | MSigDB lists | WANG_HCP_PROSTATE_CANCER | 107 | 26 | 17758 | 2588 |
REC8,CD55,CDKN1C,JRKL,NR3C1,TCFL5,DNAJB2,SLC39A8,FAM134A,FTH1,TP53I3,BMP2K,TACC2,HOXA9,SECTM1,E2F1,CCDC69,SGK1,TWIST1,CTSA,PDXK,CITED2,GAD1,LAMP3,CYP1B1,DUSP1 |
| 5.178e-03 | -5.26 | V$ETF_Q6 | MSigDB lists | V$ETF_Q6 | 107 | 26 | 17758 | 2588 |
ELK4,CELSR2,SLC41A1,VAMP3,CLSTN1,CAMK1D,POMGNT1,HPCAL4,XPR1,ZFYVE9,SOX13,CTNNBIP1,CRTC2,RNF220,ZNF687,ARTN,LRRN2,CCDC6,LMO4,C1orf21,UNC5B,C1orf43,WNT3A,SCYL3,CAMK2G,RUSC1 |
| 5.184e-03 | -5.26 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | 189 | 41 | 17758 | 2588 |
PLA2G4A,DNAJC3,CNOT8,ABCG2,KCTD12,KIF2C,ECI1,SIRPA,RCN1,PFKL,PLCG2,CKS1B,ECI2,ABCD1,PIK3CD,PTPRE,TRAM1,CDKN2D,SLC35A1,GM2A,TMX1,MAP3K3,PPIF,PMPCB,PTPN18,BNIP3L,NUSAP1,GTF2A2,ANLN,C3orf58,RHOB,PIAS3,AP1AR,TIMM8A,PEX2,PPP2R4,AURKA,RELL1,CCNB2,SRSF9,FBXW5 |
| 5.184e-03 | -5.26 | GSE14308_TH2_VS_TH17_UP | MSigDB lists | GSE14308_TH2_VS_TH17_UP | 189 | 41 | 17758 | 2588 |
CASP3,PCOLCE,CIT,ERCC6L,PBX3,STIL,ELMOD2,HMGXB4,CAPN2,FLII,OSBPL3,FAM20B,FAM63A,MAPK11,PIK3CD,WBP4,ITM2C,SLC35A1,ENPP4,KRT80,CAMSAP3,MRPS33,TRIM8,LAP3,ASPM,LPGAT1,AK4,CCBL2,CDCA2,ESYT1,ANKRD29,MFSD2A,SIPA1L1,RYK,PPM1H,TDRD7,SP6,CENPE,ARPC2,ESPL1,E2F8 |
| 5.184e-03 | -5.26 | GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN | 189 | 41 | 17758 | 2588 |
PLA2G4A,SERPINE2,ATP9A,ADO,SDC4,NDC80,ETNK1,CDCA8,FLOT1,PHLDA1,PDIA4,UHRF1BP1L,IER3,TOP2A,CCNA2,CA2,PAPSS1,MSH2,CKS1B,AHCY,RNASEH2A,ALDH3A2,CKS2,PPIF,ZWINT,PBK,KIF20B,GGH,NUSAP1,GTF2A2,KIF11,CDK1,RHOB,VCP,DCTN6,PTGS2,PRDX3,RAB11FIP1,CAB39,NUP37,ACOT7 |
| 5.184e-03 | -5.26 | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP | 189 | 41 | 17758 | 2588 |
AVPI1,MRPS15,ERI2,TRAPPC8,FAM91A1,PATL2,CMTM6,SDF4,SSX2IP,XPR1,IER3,CEP97,CASC4,TRPC1,GLB1L2,PIM1,PIKFYVE,EGLN3,DLG3,ARMCX6,KCTD3,TMBIM1,CTH,SEC23A,BAG4,DCAF6,GLO1,YES1,HEATR5A,MCFD2,CRISPLD2,CDK5RAP1,IL1R1,HLA-B,ARHGEF19,PVRL2,BHLHB9,LRIG1,EHD1,ARHGEF4,FAM45A |
| 5.184e-03 | -5.26 | YES1 (YES proto-oncogene 1, Src family tyrosine kinase) | protein interactions | 7525 | 89 | 24 | 16036 | 2547 |
PIFO,FAF2,SLC16A14,TRAF2,FLOT1,YES1,FXR2,CBL,EGFR,RASA1,SOCS3,CD46,FYN,CDH1,PAK2,NFKBIA,ANKRD12,ADAM15,ARRB1,CDKN1B,CTNND1,LIMCH1,PTPRE,OCLN |
| 5.191e-03 | -5.26 | MARSON_FOXP3_TARGETS_UP | MSigDB lists | MARSON_FOXP3_TARGETS_UP | 61 | 17 | 17758 | 2588 |
SH3BGRL,S100A4,TGFBR1,DUSP4,ETS1,CYB5A,RAC2,SWAP70,SNX18,CAPG,ITGAV,TIAM1,ITM2C,CD81,S100A6,GM2A,EPHX1 |
| 5.191e-03 | -5.26 | LEE_LIVER_CANCER_MYC_TGFA_UP | MSigDB lists | LEE_LIVER_CANCER_MYC_TGFA_UP | 61 | 17 | 17758 | 2588 |
PSRC1,IGFBP6,PLSCR1,CD63,USP18,NDRG1,HTATIP2,CYP39A1,ICAM1,ELF3,CCND1,BTG3,RPL12,ETS2,RALB,AKR1B1,TAGLN2 |
| 5.191e-03 | -5.26 | CHANG_IMMORTALIZED_BY_HPV31_DN | MSigDB lists | CHANG_IMMORTALIZED_BY_HPV31_DN | 61 | 17 | 17758 | 2588 |
THRB,MX1,TNRC6C,PTPRU,P2RX7,KLK6,SAMD9,FOS,MXD1,NMT2,PRIM1,PTGS2,PHF7,STAT1,KLK7,IFIT1,SULT2B1 |
| 5.191e-03 | -5.26 | MODULE_254 | MSigDB lists | MODULE_254 | 61 | 17 | 17758 | 2588 |
PLK1,MX1,LGALS3,DNAJC3,CDC20,BIK,MYBL2,BNIP3L,BCL2L1,CCNB1,STK17B,FAS,IER3,BCAR3,WEE1,PCNA,E2F1 |
| 5.198e-03 | -5.26 | regulation of canonical Wnt signaling pathway | biological process | GO:0060828 | 229 | 49 | 16441 | 2455 |
CTHRC1,LGR4,PSME2,SOX9,LRP4,PSMD7,XIAP,PSMD10,AES,PSME1,ZNRF3,APC2,KREMEN1,FZD6,PPP2R3A,CDK14,BMP2,PSMD1,RNF220,CTNNB1,DACT1,PSMC2,DAB2IP,DIXDC1,WNT3A,PSMA5,DVL2,WNT10B,PSMB4,KREMEN2,ASPM,AMER1,PRICKLE1,ILK,NPHP3,PSMA4,ANKRD10,GPRC5B,FGFR2,ANKRD6,PSMD3,TBX18,NKD1,WWTR1,CTNND1,LRRK1,FZD5,PSMC1,RNF146 |
| 5.199e-03 | -5.26 | cervix-carcinoma | COSMIC cancer mutations | cervix-carcinoma | 42 | 13 | 17775 | 2585 |
CDKN2C,RB1,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR |
| 5.208e-03 | -5.26 | ear morphogenesis | biological process | GO:0042471 | 115 | 28 | 16441 | 2455 |
CTHRC1,SOD1,USH1C,SOX9,GATA3,SCRIB,OSR2,PRKRA,SIX4,FZD6,ABR,GBX2,GATA2,FGFR2,TBX1,PTK7,LRIG1,TBX18,ALDH1A3,NR4A3,TFAP2A,TWIST1,WNT3A,NTN1,OSR1,GFI1,SPRY2,DVL2 |
| 5.210e-03 | -5.26 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | 223 | 47 | 17758 | 2588 |
MAN2B2,GALK1,PCOLCE,CEP70,IL15RA,ENO2,NDRG1,PDIA5,PKP2,EFHD2,CYB561,JAG2,SH3KBP1,KIAA1161,ABCD4,PER2,C16orf74,ELMO2,GATA2,ELF5,CAPG,ABCA2,GYS1,CRY2,KLF9,EPB41L4B,RAB27B,MYBL1,DUSP1,TMCC2,GCLC,SPATA13,KDELR3,TXNDC11,MAP1B,NIN,ATP13A2,NAAA,P4HA2,MPP2,DGAT2,PDXK,SERPINB1,JARID2,EHD1,USP43,EGLN1 |
| 5.214e-03 | -5.26 | env (gp160; envelope glycoprotein) | protein interactions | 155971 | 1401 | 257 | 16036 | 2547 |
SUN1,LAMP1,GAA,ACVR1,TXN,IL15RA,HSPG2,DNAJC3,OAT,CCNB1,BARD1,CHST2,CALM2,AP1M2,PIK3CA,DNM2,TUBG1,CLDN4,PIK3CD,TIPARP,APOBEC3G,TUBA4A,DSTN,CASP9,SLC25A5,ARF4,LCP1,ABR,SFXN1,PIAS3,PLCG1,LIMK1,MAP3K11,MAPK13,ARF6,TRAF5,MRC2,HLA-E,TSPAN7,ELF3,MESDC2,CALR,ITGA3,TPST1,CTSD,MAPK7,EEF1D,STAT4,CALM1,PYGL,PLS1,FAM133B,SRSF5,PKM,GLT8D2,GNA11,FAS,STK17A,TIMM8A,SEMA4D,MAP3K5,ARPC2,PLIN3,PLA2G4A,CAPN12,REPS2,NQO1,TUBB4B,ST14,IQGAP1,INPP5D,CD82,FTH1,MAPK4,CD274,BCL2L1,PRKACA,SP100,CDH1,CDKN1B,LGMN,TMEM43,PRKCQ,FYN,DDOST,JAK1,STAT1,PPP1CB,FAM195A,B4GALT3,PRKAR1A,MAPK12,HSP90B1,MAN1A2,SDC4,FLOT1,PDIA3,PLD2,FBXO6,SEPP1,LGALS3BP,HLA-A,ICAM1,PDIA4,CAPN2,CXCL16,PTEN,MGAT1,MGAT4A,ALG13,FUT8,CD9,BAX,MAPK11,TAGLN2,MAP3K7,RASGRF1,ADAMTS2,PLSCR1,PIK3R1,GRIN1,FURIN,FOS,PRDX3,ABCB1,GRIN2D,ITGAV,CD81,OCLN,CASP3,UGT8,CPT2,DNAJB11,F11R,MGAT5B,HDAC6,CDIPT,PDGFB,MAP1LC3B,SDC1,DNER,PLS3,CTNNB1,P4HB,ARL1,SIVA1,DLG1,ARNT2,LAMP3,CD55,SOD1,ACBD3,CR2,EZR,ERP44,PTGFRN,CDK1,VCP,MAN2A2,PLCH1,KCNMB4,MAP2,P4HA2,MADD,RAB11FIP1,PIK3C2B,CAPN1,PCSK5,RUNX2,HLA-F,PSMD7,CALM3,NCKAP1,RAB6A,B4GALT4,IL18R1,B3GALNT1,RB1,IGF1R,KCNN4,PAK2,PRKCI,HLA-C,GAD1,PLCB2,CKAP4,ABCC1,MGAT4B,MAPKAPK2,CSF1,NFKBIA,PLD1,JAK3,IFI6,UPF3B,IL15,TP53,PDIA5,SOD2,P2RX7,PCBP1,BCAP31,SDF4,IER3,PLCG2,BCL6,OAS3,NFKB2,LMAN1,PDIA6,HSPA2,ERLEC1,AKT1,CD40,CDC25C,SOCS3,ARHGAP35,PTGS2,ATP1A1,ST3GAL1,MAN2B2,CD63,CTSB,SELL,NKRF,COL4A5,NRP2,VPS26A,TOP2A,ALPP,BMP7,GTF2F2,TFAP2A,ACTA2,HSPA13,RHOA,IFITM3,PLAUR,TTC7A,RUNX3,TRIM35,DDX23,CD83,PRDX4,FUCA1,CTSL,ENDOD1,CD8A,HLA-B,SERPINA1,HNRNPH2,CTSV,PGRMC1,E2F1,SPCS3,PTGES,GOLGB1 |
| 5.217e-03 | -5.26 | Role of LAT2/NTAL/LAB on calcium mobilization | REACTOME pathways | R-HSA-2730905 | 104 | 26 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,PDGFA,IRS2,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,ERBB3,PIK3CD,SYK,GAB1 |
| 5.218e-03 | -5.26 | transition metal ion binding | molecular function | GO:0046914 | 1395 | 241 | 16491 | 2452 |
UNKL,TRIM2,TRIM24,TRIM5,XIAP,LMCD1,GATA3,SYTL4,CDIPT,HDAC6,PJA2,CA8,BARD1,PHF1,TRIM68,ZYX,CYP1A1,ZCCHC12,PRICKLE3,SIVA1,MKRN3,CYP2S1,AOX1,NFU1,MARCH2,WBP4,RNF26,MYRIP,CPE,S100A13,APOBEC3G,RASGRP1,ERAP2,CYP1B1,THRB,NEK4,PCGF5,VPS11,SOD1,CXXC5,TRIM8,ING1,LAP3,RNF11,CDA,RNF165,LOXL2,RNF19B,ZFAND5,TP53I3,CYP4F3,POR,PIAS3,CXXC4,MAN2A2,TRIM9,ENPP1,TRIM47,NEIL1,P4HA2,PTER,LIMK1,ATP7B,TRIM45,BMP1,TRAF5,NR2C2,DDX58,LASP1,CYP2J2,ZCCHC24,ZNRF3,RABGGTA,SH3RF2,MARCH8,CALR,DNPEP,ZCCHC17,WDFY1,CA2,FAM20C,GATA2,ZNRF2,PRICKLE4,LIMCH1,PIM1,ZMYM1,ZRANB1,MOXD1,MYLIP,ZNF117,CYP26B1,PMPCB,ZNF84,MFI2,SHARPIN,GYLTL1B,FHL2,WHSC1,RNF113A,KDM3A,JADE2,ZDHHC3,G2E3,DCP2,FECH,MMP15,NUDT16,FA2H,ZDHHC20,P4HA3,S100A5,PIAS2,AGBL5,ZDHHC7,NR4A2,ZDBF2,DRP2,IFIH1,RARG,RNF146,CSRP2,KLF7,XDH,ADAMTS16,EGLN1,LMO7,RNF224,ZSWIM5,THRA,P3H2,TP53,SOD2,MORC4,RNF182,FTH1,MICALL2,CYP39A1,CYP26A1,ZNF385B,APOBEC3B,CYHR1,APLP2,RNF220,ZNF75D,SETDB2,CYP4F11,LMO4,ZDHHC12,LHX6,ZDHHC23,VAT1,APIP,ETHE1,EGLN3,LOXL1,MYT1,NR2C1,RNF169,CPD,SEC23A,APOBEC3D,UTRN,COX11,GLO1,SLC11A2,PYGO1,CBL,TRIM7,AMZ2,JADE1,IDE,PDLIM3,MMP17,PEX2,ADAMTS14,PDXK,CYP2U1,LTA4H,NR3C2,ZC3HC1,MAN2B2,ZMAT1,FBLIM1,TAB3,SHPRH,TRAF2,ERI2,CBLL1,APOBEC3H,ZNF212,ZDHHC21,DTX3L,RNF128,PHF7,ALPP,ZFAND4,ZDHHC13,ADAM15,TRIM3,TRIM21,HMGCL,RAG1,GFI1,TRIM62,S100A6,P2RX4,ADAMTS2,PHF20L1,ADAM17,LONRF3,NR3C1,AMFR,NR4A1,CRIP2,RC3H2,PPARA,PRICKLE1,TRIM35,BLVRA,NEURL1B,RNPEP,ABLIM2,GALNT3,MARC1,PLOD2,TRIM69,ATXN7L3,NR1D2,NEIL3,ZNF214,DTX4,NR4A3,TADA2B,ERAP1,FHL1,ZMIZ1,PLOD3,USP16,TLL2,PHC1 |
| 5.234e-03 | -5.25 | lung-right_upper_lobe-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-right_upper_lobe-carcinoma-bronchioloalveolar_adenocarcinoma | 6 | 4 | 17775 | 2585 |
KIF5B,ERBB2,EGFR,TP53 |
| 5.234e-03 | -5.25 | bone-other-chondroma | COSMIC cancer mutations | bone-other-chondroma | 6 | 4 | 17775 | 2585 |
GNAS,ERBB2,IDH1,TP53 |
| 5.234e-03 | -5.25 | meninges-meningioma-angiomatous | COSMIC cancer mutations | meninges-meningioma-angiomatous | 6 | 4 | 17775 | 2585 |
CDKN2C,NF2,AKT1,SMO |
| 5.234e-03 | -5.25 | angiomatous | COSMIC cancer mutations | angiomatous | 6 | 4 | 17775 | 2585 |
CDKN2C,NF2,AKT1,SMO |
| 5.234e-03 | -5.25 | lung-right_middle_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-right_middle_lobe-carcinoma-adenocarcinoma | 6 | 4 | 17775 | 2585 |
ERBB2,EGFR,PIK3CA,TP53 |
| 5.234e-03 | -5.25 | spindle_cell | COSMIC cancer mutations | spindle_cell | 6 | 4 | 17775 | 2585 |
GNAS,RB1,IDH1,PIK3CA |
| 5.234e-03 | -5.25 | psammomatous | COSMIC cancer mutations | psammomatous | 6 | 4 | 17775 | 2585 |
CDKN2C,NF2,AKT1,SMO |
| 5.234e-03 | -5.25 | endometrium-carcinoma-mixed_endometrioid_and_clear_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mixed_endometrioid_and_clear_cell_carcinoma | 6 | 4 | 17775 | 2585 |
CTNNB1,FGFR2,PTEN,PIK3CA |
| 5.234e-03 | -5.25 | TSH | COSMIC cancer mutations | TSH | 6 | 4 | 17775 | 2585 |
GNAS,CDKN2C,RET,PIK3CA |
| 5.234e-03 | -5.25 | meninges-meningioma-psammomatous | COSMIC cancer mutations | meninges-meningioma-psammomatous | 6 | 4 | 17775 | 2585 |
CDKN2C,NF2,AKT1,SMO |
| 5.234e-03 | -5.25 | pituitary-adenoma-TSH | COSMIC cancer mutations | pituitary-adenoma-TSH | 6 | 4 | 17775 | 2585 |
GNAS,CDKN2C,RET,PIK3CA |
| 5.252e-03 | -5.25 | GNF2_PTPRC | MSigDB lists | GNF2_PTPRC | 66 | 18 | 17758 | 2588 |
KLF2,HECA,PARP12,HLA-E,HLA-F,TSC22D3,GRK6,HLA-A,HLA-B,RAC2,MSL1,JAK1,SEMA4D,STK38,RIN3,OSTF1,HLA-C,ARHGAP4 |
| 5.259e-03 | -5.25 | RB in Cancer | WikiPathways | WP2446 | 87 | 24 | 4455 | 729 |
CCNE2,SMARCA2,TP53,ANLN,CCNB1,POLD3,BARD1,CDK1,PRIM1,TOP2A,CCND1,RB1,WEE1,CCNA2,PCNA,CCDC6,DCK,E2F1,PLK4,HDAC1,CDKN1B,MAPK13,CCNB2,MSH6 |
| 5.263e-03 | -5.25 | MODULE_154 | MSigDB lists | MODULE_154 | 71 | 19 | 17758 | 2588 |
KLK10,KLK5,LMTK3,KLHL13,FXYD3,ITGA6,COL7A1,PPP1R14C,S100A2,EFNB1,CYP26A1,PTGS2,CA2,AREG,ALDH1A3,SERPINB5,MAOA,CDH3,F2RL1 |
| 5.263e-03 | -5.25 | GU_PDEF_TARGETS_UP | MSigDB lists | GU_PDEF_TARGETS_UP | 71 | 19 | 17758 | 2588 |
DOCK4,COL6A2,FZD4,ITGA6,COL4A5,SDC1,MAPKAPK2,BMP2,RAC2,PLCG1,ITGA3,SERPINA1,CTGF,COL13A1,COL6A1,HDAC1,SERPINI1,PIK3CD,COL16A1 |
| 5.263e-03 | -5.25 | GNF2_SPTB | MSigDB lists | GNF2_SPTB | 71 | 19 | 17758 | 2588 |
TMCC2,GCLM,ERMAP,HEBP1,MPP1,BLVRB,BNIP3L,EIF2AK1,UBAC1,SPTB,RAD23A,FECH,MARCH8,ANK1,CA2,H1F0,FBXO7,MINPP1,TRAK2 |
| 5.263e-03 | -5.25 | ROSS_AML_WITH_PML_RARA_FUSION | MSigDB lists | ROSS_AML_WITH_PML_RARA_FUSION | 71 | 19 | 17758 | 2588 |
PRODH,MRC2,AGRN,CDKN1C,TMX4,ARFGEF1,ITPR2,ALCAM,RCN1,CALR,P4HB,GALNS,CLMN,TLE1,IGFBP2,MANF,ARHGAP4,SLC25A38,GCNT1 |
| 5.263e-03 | -5.25 | GNF2_ANK1 | MSigDB lists | GNF2_ANK1 | 71 | 19 | 17758 | 2588 |
TMCC2,GCLM,ERMAP,HEBP1,MPP1,BLVRB,BNIP3L,UBAC1,EIF2AK1,SPTB,RAD23A,FECH,MARCH8,ANK1,CA2,H1F0,FBXO7,MINPP1,TRAK2 |
| 5.263e-03 | -5.25 | CAGNYGKNAAA_UNKNOWN | MSigDB lists | CAGNYGKNAAA_UNKNOWN | 71 | 19 | 17758 | 2588 |
TGIF1,NR3C1,WDTC1,CACNA2D2,SOD2,PLAC1,SYTL4,TRIB2,ETS1,PRKACA,TNFRSF19,HOXB2,APPBP2,PITX2,BMP1,PPP1CB,FAM117A,PDE4D,TRAM1 |
| 5.276e-03 | -5.24 | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_DN | MSigDB lists | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_DN | 6 | 4 | 17758 | 2588 |
SERPINB1,PLOD2,MCF2L,EDNRA |
| 5.276e-03 | -5.24 | ZERBINI_RESPONSE_TO_SULINDAC_DN | MSigDB lists | ZERBINI_RESPONSE_TO_SULINDAC_DN | 6 | 4 | 17758 | 2588 |
CCNB1,CDC25C,CCNB2,CDK1 |
| 5.276e-03 | -5.24 | MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_DN | MSigDB lists | MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_DN | 6 | 4 | 17758 | 2588 |
AKR1B1,OAT,CTSD,HSPB1 |
| 5.276e-03 | -5.24 | IWANAGA_E2F1_TARGETS_NOT_INDUCED_BY_SERUM | MSigDB lists | IWANAGA_E2F1_TARGETS_NOT_INDUCED_BY_SERUM | 6 | 4 | 17758 | 2588 |
CDKN1B,CCNA2,ARHGEF26,NEO1 |
| 5.283e-03 | -5.24 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | 178 | 39 | 17758 | 2588 |
RPS6KA1,CD82,ITGA6,XYLT1,GMPR,EGR3,KBTBD11,TEAD3,ITGA2B,CCND1,ANK1,MGAT1,GATA2,KCNK5,CAPG,DUSP10,IL17RA,IGFBP2,FLOT2,TPCN1,CKAP4,CYP1B1,TUBA4A,FADS2,CD55,MBP,S100A4,FHL2,RUNX3,C15orf39,PLCH1,TIMP3,LDLRAP1,CSF1,NOD2,PDXK,RGS14,E2F8,CD33 |
| 5.283e-03 | -5.24 | MODULE_93 | MSigDB lists | MODULE_93 | 178 | 39 | 17758 | 2588 |
ALDH6A1,NQO1,CYP2J2,BLVRB,PDIA3,NDUFA4,COX6C,SPR,DHRS3,ERP29,CYP26A1,COX7A2,PDIA4,CYP1A1,P4HB,SIVA1,ALDH1A3,AOX1,AKR1B1,ALDH7A1,ACOX2,ALDH3A2,GPX4,CYP1B1,QSOX1,FADS2,SOD1,IDH1,TP53I3,PRDX4,ALDH3B1,ALDH5A1,ACADSB,DHRS2,MAOA,MDH1,ACADM,PLOD3,XDH |
| 5.295e-03 | -5.24 | LIU_TARGETS_OF_VMYB_VS_CMYB_DN | MSigDB lists | LIU_TARGETS_OF_VMYB_VS_CMYB_DN | 42 | 13 | 17758 | 2588 |
MAPKAPK2,ARHGAP24,PDGFA,PTPRJ,USP31,TSC22D3,CSGALNACT1,GATA3,FAM117A,KLF5,EAF2,FAM45A,EHD1 |
| 5.295e-03 | -5.24 | AMIT_EGF_RESPONSE_120_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_120_MCF10A | 42 | 13 | 17758 | 2588 |
TESK1,PLAUR,ALDH1A3,PPP2R4,APOO,BAX,TRIM21,GDF15,SPRY4,PHLDA1,MAFF,GPR161,BCL10 |
| 5.302e-03 | -5.24 | small_intestine-duodenum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-duodenum-carcinoma-adenocarcinoma | 33 | 11 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,AKT1,RET,MSH2,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 5.311e-03 | -5.24 | ureteric bud morphogenesis | biological process | GO:0060675 | 55 | 16 | 16441 | 2455 |
HES1,FMN1,DCHS1,SOX9,GATA3,ILK,CTNNBIP1,BMP2,CTNNB1,FAT4,NPNT,GPC3,DLG1,TACSTD2,PKD2,ADAMTS16 |
| 5.319e-03 | -5.24 | MODULE_119 | MSigDB lists | MODULE_119 | 134 | 31 | 17758 | 2588 |
MX1,ARAP2,IL15,STAT4,SYNE2,PTTG1,DGKA,SELL,CR2,PRKCQ,GMCL1,TRIB2,CYFIP2,BBS2,HLA-A,IL1R1,NOV,FYN,BANK1,FASTKD1,KLF12,PASK,SPINT2,ABCB1,NLRC5,PIK3C2B,IRF7,ARMCX6,APOBEC3G,RRAGD,IRF1 |
| 5.319e-03 | -5.24 | SMID_BREAST_CANCER_ERBB2_UP | MSigDB lists | SMID_BREAST_CANCER_ERBB2_UP | 134 | 31 | 17758 | 2588 |
CPD,PRODH,PLEKHA6,PAPSS2,SLC37A1,NQO1,GCAT,ATP2C2,BIK,ERBB2,CYB561,IL13RA1,SPTLC2,ALCAM,CORO1B,MMP15,CD46,NCOA3,SCNN1A,FA2H,PPP1R10,P4HB,PSMD3,TMC5,AIM1,TRIM3,GOT1,C2orf72,TSPAN1,TMED2,SNPH |
| 5.321e-03 | -5.24 | EHD1 (EH domain containing 1) | protein interactions | 10938 | 61 | 18 | 16036 | 2547 |
PLA2G4A,DGKQ,PRKRA,NUBP1,KTN1,VPS26A,EGFR,FAS,EPN3,PDCD10,WDFY1,IGF1R,RAB11FIP2,STAT6,STK39,TECR,HSPB1,EHD1 |
| 5.321e-03 | -5.24 | F-box-assoc_dom | interpro domains | IPR007397 | 6 | 4 | 18293 | 2672 |
FBXO44,FBXO6,FBXO27,FBXO2 |
| 5.321e-03 | -5.24 | PET_domain | interpro domains | IPR010442 | 6 | 4 | 18293 | 2672 |
PRICKLE1,PRICKLE3,PRICKLE4,LMCD1 |
| 5.321e-03 | -5.24 | p53/RUNT-type_TF_DNA-bd | interpro domains | IPR012346 | 6 | 4 | 18293 | 2672 |
TP73,RUNX3,RUNX2,TP53 |
| 5.321e-03 | -5.24 | Kinesin_assoc | interpro domains | IPR032405 | 6 | 4 | 18293 | 2672 |
KIF1C,KIF13A,KIF14,KIF13B |
| 5.321e-03 | -5.24 | Hydantoinase/dihydroPyrase | interpro domains | IPR011778 | 6 | 4 | 18293 | 2672 |
DPYSL5,DPYSL4,DPYSL2,DPYSL3 |
| 5.340e-03 | -5.23 | ER_TARGET | prosite domains | PS00014 | 45 | 14 | 11866 | 1802 |
CALR,RCN1,DNAJC10,HSP90B1,P4HB,CERCAM,P3H2,PDIA5,ERP44,MINPP1,PDIA6,ERP29,KDELC2,PDIA4 |
| 5.355e-03 | -5.23 | ADENYL_NUCLEOTIDE_BINDING | MSigDB lists | ADENYL_NUCLEOTIDE_BINDING | 167 | 37 | 17758 | 2588 |
GALK1,TNK1,ACVR1,DYRK3,PINK1,PEX6,ABCG2,TP53,TGFBR1,AIFM2,ABCD4,DAPK2,CDKL5,PRKCI,ABCA2,MSH2,DAPK1,PIM1,MSH6,SMC4,ABCC1,SEPHS1,MARK1,GCLC,PIF1,MAP3K6,STK17B,DGKE,STK17A,ACVRL1,STK38,ATP7B,PPP2R4,ABCB1,MAP3K5,DMPK,ABCG1 |
| 5.362e-03 | -5.23 | CCND3 (cyclin D3) | protein interactions | 896 | 52 | 16 | 16036 | 2547 |
KLK5,CDKN1C,MAPK4,CRABP2,NPDC1,CDK1,CDK14,FAS,CDKN2C,RB1,PCNA,AREG,CDKN1B,PPP1CB,PPP1CA,NCOA2 |
| 5.365e-03 | -5.23 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | 2630 | 426 | 17775 | 2585 |
FAM171B,ACVR1,FAM160B1,AASS,AK7,ATP8A1,DNAJC3,CACNA2D2,PPFIBP2,FBXO2,PDGFRL,PLXNA1,LACTB2,VASH1,SNX9,ZNF275,SLC9A7,CDKN2C,ARHGAP42,DNAH6,CYP2S1,ATP13A3,AOX1,PIK3CA,ATRNL1,CRY2,CPE,MGAT5,ERAP2,TNIP1,SH3BGRL,CDA,SLC35C1,PRKAR2B,TNS1,LOXL2,GALNT7,AURKB,LDB2,MYOM1,LCP1,AHRR,GRID2IP,ATP7B,PRDM5,AGFG2,MRPS28,WBSCR27,GAB1,DLAT,DDX58,MRC2,FRMD4A,TBC1D1,SLC25A27,ZNRF3,SLC1A3,GPSM2,NOTCH2,APBA1,PDXDC1,TTYH3,ELF3,FRY,FAM189A1,CD22,AIM1,MSH2,PRKG1,SORL1,CADPS2,OSTF1,ALPK1,STT3B,CACNA1D,NCAM1,MYLIP,ULBP2,KCTD3,C9orf72,EEF1D,MCCC2,GFPT1,DDB2,KLK5,SLC37A1,KIF20A,CEP89,TBC1D8B,SALL4,AMER1,DCHS1,FHL2,PYGL,PKM,NPHP3,ANTXR1,PCTP,SFXN5,FBXO10,PSMA4,GNA11,NFIB,DCP2,CYB5A,PDE11A,PTPRF,DGKH,CACHD1,SLCO4A1,NT5C2,GABRD,HTT,PELI2,DCK,C1orf21,ITPR1,APPL2,DYSF,PCDH19,CABIN1,PLIN3,HOOK1,PKD1L2,RNF224,TCTN2,CAPN12,ST14,C5orf30,RGS20,PKP2,MOCS1,REPS1,ZNF385B,APOBEC3B,MUC16,CDH1,RALB,LRP11,MYO5B,ERMP1,NRBF2,FOXJ2,SYNE2,UTRN,TMEM144,PRKCQ,CBL,XRCC6BP1,ITPR3,ALCAM,EBF2,ZMPSTE24,CMTM7,FYN,CCNB3,SHROOM3,TTC12,SLC27A1,NRG1,ZC3H12B,SLC27A3,NR3C2,COBL,MAMDC2,OTUD5,MRPS9,ARHGEF3,MPZL1,FAM189A2,BACE1,TRAF2,EPS8,BTN3A1,PBX3,CYB561,DNAH3,IFT27,CKAP5,ITGB8,IGSF9,RNF128,ANKS1B,FAM160A2,CALD1,MGAT4A,FUT8,SGK3,PLEKHF1,AK3,RAG1,CASD1,NCOA2,MSH6,PARP9,FARP2,PVRL4,ADAMTS2,PDGFC,CASK,ARAP2,LCA5,FAM160A1,PAPD7,TCFL5,RAPGEF2,PIK3R1,CXorf57,FURIN,DIAPH2,EMP3,YES1,SNTB1,SKA1,ACADSB,PLOD2,RAB11FIP2,ACVRL1,CSTF2,ITGAV,WDR62,CYBRD1,MELK,TMEM131,ESYT2,JARID2,LTBP1,FAF2,UGT8,FAM199X,EPHA4,CUL4B,FHDC1,ARFGEF1,NDC80,UBE2Z,ITPR2,DNER,KREMEN1,TMC1,SPTB,SH3KBP1,PLS3,NKAIN3,HSF2,CDKL5,NPNT,DPYSL2,TSPAN6,PAPSS1,SLC44A1,ANKFN1,DLG1,POF1B,NTN4,MYH14,ANO4,TECR,SLC39A10,MYRIP,NEB,LAMP3,ZNF462,OLFML2A,THRB,MCTP1,ASXL1,ITCH,RNF165,CR2,ERP44,ROR1,PRKRA,IDH1,SESN1,PTGFRN,RHEB,EDNRA,TNS4,HS6ST1,PI4K2B,KCNMB4,KLF12,FASTKD1,EPB41L4A,CAPN1,HS6ST3,GRN,PARP12,UBASH3B,ELOVL7,RACGAP1,CNTNAP2,FAM81A,PHLPP1,DHRS3,FBLN1,TNS3,AIM1L,DAZAP1,CA2,IGF1R,FRAS1,PRKCI,LIMCH1,KNTC1,NTN1,GAD1,MPHOSPH9,ALS2CL,CKAP4,SNX7,CHSY3,PODXL2,PLEKHA6,WDR72,CORO2A,ZNF320,KIAA1109,HEATR5A,RASGRP2,BCAR3,TSC1,CSF1,LTBP2,ZDBF2,SHROOM2,SEMA3A,RARG,SNX30,RAD21,LMO7,NCKAP5,TMX4,TP53,PDIA5,COL18A1,RHPN2,EXT2,CYP26A1,KCTD9,CDK14,TTC21B,SRPX,EFR3A,TACC2,WDR44,EPB41L4B,NOTCH3,OAS3,FAR1,TMTC1,MBP,C3orf52,ACO1,TMTC2,DOCK5,PDHX,DNAJC10,PTPRJ,RBL1,ABHD12,PTK7,TLE1,MAOA,CHMP4B,EFNA5,LIFR,CBX4,FAM134B,CMAS,GOLIM4,TRAPPC10,ARHGEF11,POC1B,SH3D19,SCD5,MCTP2,GABRG2,SELL,HMGN3,POMGNT1,LBR,IL22RA1,PPP2R3A,SLC9A2,FZD6,NRP2,ZDHHC21,MLPH,LLGL2,LYPD6,BMP7,UBE2J1,SLC35B4,KIAA0319,CPLX1,KLF9,MYO5A,DLGAP1,HMMR,RAB3B,CRB3,NR3C1,AMFR,PHLDB3,ASPM,PPARA,LRRC66,TTC7A,DPP9,MAML2,DGKE,MAP1B,USP6,KLHL2,HLA-B,DDAH1,BANK1,SWAP70,TWSG1,OTUB2,ZMIZ1,PLOD3,ATP6V1C1,NGEF |
| 5.372e-03 | -5.23 | GSE17721_CTRL_VS_LPS_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_12H_BMDM_DN | 195 | 42 | 17758 | 2588 |
GOLIM4,IL15RA,GRIK2,CRYM,CD82,TAP1,DNAJB11,DNER,REPS1,KREMEN1,ITGA2B,KIAA1161,RAD23A,SPP1,RPS6KA2,ADRBK1,TIMP1,RANBP1,H2AFY,CITED2,SNX10,C9orf72,CPD,MOB4,PMPCB,NRBF2,PARD3B,KLK6,SPTLC2,EGFR,PVRL2,GDE1,PLK2,TMEM30A,HDAC1,KLF5,SLC27A1,RBM43,SLC25A38,SHOX2,PPP2R2D,JARID2 |
| 5.372e-03 | -5.23 | GSE17721_CTRL_VS_LPS_4H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_4H_BMDM_DN | 195 | 42 | 17758 | 2588 |
WASF3,LZTFL1,GRHL2,TSPAN15,PARP14,FRMD6,IQGAP1,SERPINB9,IL18,CCNL1,BCL2L1,CA8,IER3,TIMP1,LMO4,SLC44A1,CD70,WNT3A,RAG1,IL10RB,TMEM9,SMAGP,GCA,ZC3H11A,NR4A1,SLC39A8,KLK6,PSMA4,EGFR,ARHGAP35,CARHSP1,RBM47,PVRL2,FAAH,PRKCDBP,RCAN2,ARF6,RBM43,TRAF5,E2F8,HOXC13,JARID2 |
| 5.382e-03 | -5.22 | glutamate metabolic process | biological process | GO:0006536 | 28 | 10 | 16441 | 2455 |
GCLM,PRODH,ALDH5A1,GCLC,HAL,GOT1,SLC1A3,OAT,GAD1,AMDHD1 |
| 5.382e-03 | -5.22 | hippo signaling | biological process | GO:0035329 | 28 | 10 | 16441 | 2455 |
AMOTL2,CASP3,FAT4,WWTR1,DCHS1,PJA2,SAV1,TEAD3,DVL2,DMPK |
| 5.382e-03 | -5.22 | RhoGAP_dom | interpro domains | IPR000198 | 66 | 18 | 18293 | 2672 |
ARHGAP11A,ARAP3,ARAP2,DEPDC1,RALBP1,PIK3R1,RACGAP1,ABR,SYDE2,ARHGAP35,ARHGAP24,ARHGAP42,SH3BP1,OCRL,FAM13B,ARAP1,ARHGAP4,STARD13 |
| 5.390e-03 | -5.22 | GNF2_CD48 | MSigDB lists | GNF2_CD48 | 33 | 11 | 17758 | 2588 |
HLA-B,TAPBP,RAC2,HLA-E,HLA-F,STAT6,INPP5D,ARHGDIB,GRK6,HLA-C,HLA-A |
| 5.390e-03 | -5.22 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | MSigDB lists | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | 33 | 11 | 17758 | 2588 |
SEC23A,MGAT1,MAN1A2,MGAT4A,FUT8,MGAT4B,MCFD2,B4GALT4,B4GALT3,LMAN1,MGAT5 |
| 5.390e-03 | -5.22 | JIANG_HYPOXIA_VIA_VHL | MSigDB lists | JIANG_HYPOXIA_VIA_VHL | 33 | 11 | 17758 | 2588 |
IRF2BPL,SCARB2,ENO2,KBTBD2,PPP1CB,UACA,C6orf106,GTF2A2,PPP2R5D,CKAP4,WBP5 |
| 5.391e-03 | -5.22 | CSR_EARLY_UP.V1_UP | MSigDB lists | CSR_EARLY_UP.V1_UP | 156 | 35 | 17758 | 2588 |
REPS2,FRMD6,DDIT4L,SOX9,CD274,ETS1,IRAK1,GATA2,FJX1,TNFRSF12A,TFG,SPRY2,PPIF,PHF20L1,ELK3,RIPK2,RFK,RGMB,PAPD7,NRBF2,PLAUR,MRPS35,BCAR1,CRISPLD2,BCAR3,PTGS2,PLCH1,UAP1,PHLPP2,YOD1,SPRY4,HMGA1,ST3GAL1,DCBLD1,CD33 |
| 5.398e-03 | -5.22 | SUMO1 (small ubiquitin-like modifier 1) | protein interactions | 7341 | 159 | 38 | 16036 | 2547 |
PAX6,TRIM24,FOXM1,PPM1J,TRIM5,TSC22D3,TP53,GMCL1,HDAC9,TP73,TOP2A,IRAK1,SP100,ZCCHC12,MITF,SIMC1,NCOA2,MX1,PDGFC,NR3C1,PKM,FOS,VCP,FAS,NIN,PIAS3,NCOA3,PTGS2,HTT,NFKBIA,PIAS2,KLF5,ZBTB6,ARPC2,NR3C2,HIPK3,CBX4,PHC1 |
| 5.399e-03 | -5.22 | trans-Golgi network | cellular component | GO:0005802 | 177 | 39 | 17570 | 2579 |
PIFO,SCOC,BACE1,ATP9A,ARFGEF1,RGS20,TGOLN2,RAB6A,SNX9,CHST2,SLC9A7,AP1M2,CDH1,OCRL,ARL1,DNM2,SORL1,GCNT1,CPD,GCC2,LAP3,FURIN,FBXO8,KIF13A,SLC11A2,ARFRP1,RAB38,FAM109A,OPTN,GNAS,NUCB1,STX10,WIPI1,ATP7B,RAB31,ARAP1,RAB29,GPER1,ARFGEF3 |
| 5.399e-03 | -5.22 | insulin-like growth factor I binding | molecular function | GO:0031994 | 9 | 5 | 16491 | 2452 |
IGFBP2,ITGAV,INSR,IGF1R,IGFBP6 |
| 5.399e-03 | -5.22 | nitric-oxide synthase regulator activity | molecular function | GO:0030235 | 9 | 5 | 16491 | 2452 |
CALM3,CALM2,AKT1,EGFR,CALM1 |
| 5.399e-03 | -5.22 | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor | molecular function | GO:0016723 | 9 | 5 | 16491 | 2452 |
CYB561,STEAP3,STEAP1,CYBRD1,STEAP2 |
| 5.399e-03 | -5.22 | peptidyl-proline 4-dioxygenase activity | molecular function | GO:0031545 | 9 | 5 | 16491 | 2452 |
EGLN3,P4HB,P4HA2,P4HA3,EGLN1 |
| 5.401e-03 | -5.22 | LRP1 (LDL receptor related protein 1) | protein interactions | 4035 | 75 | 21 | 16036 | 2547 |
HSP90B1,PLAUR,CD82,BACE1,FURIN,FBXO6,PRKACA,PDGFB,RANBP9,MAPK8IP1,EGFR,MMP15,MDK,CALR,SERPINA1,CTGF,ANKS1B,MMP17,WNT3A,APBA2,SCN3A |
| 5.421e-03 | -5.22 | regulation of exit from mitosis | biological process | GO:0007096 | 16 | 7 | 16441 | 2455 |
NPM2,KNTC1,ANLN,MAD2L1BP,UBE2C,CDCA5,RGCC |
| 5.424e-03 | -5.22 | FAS pathway and Stress induction of HSP regulation | WikiPathways | WP314 | 38 | 13 | 4455 | 729 |
MAPKAPK2,RB1,CASP3,CASP7,RIPK2,MAPKAPK3,PAK2,CASP9,ARHGDIB,MAP3K7,HSPB1,LMNA,FAS |
| 5.425e-03 | -5.22 | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | MSigDB lists | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | 118 | 28 | 17758 | 2588 |
GRN,SPC25,KIF20A,ENO2,DLGAP5,LGALS8,NDRG1,TSC22D3,ARL4C,BNIP3L,NES,AK4,KCTD12,GDF15,PHLDA1,MAP1LC3B,DPYSL3,GABARAPL1,TOP2A,DIRAS3,KLF12,FAM64A,WIPI1,SCG2,PLK2,VAT1,MYBL1,CTH |
| 5.462e-03 | -5.21 | STK33_SKM_UP | MSigDB lists | STK33_SKM_UP | 258 | 53 | 17758 | 2588 |
UNKL,BMF,CDKN1C,CPEB4,IL15,TMTC3,LFNG,RASGRP3,PHLDA1,MNS1,DUSP5,MXD1,ZNF432,SIPA1L2,NOV,KIAA0895,ARHGAP42,KIAA1107,ITGB8,FAM20C,ZFP36,CD9,ACTA2,SGK1,SNX16,C10orf54,DUSP1,SULF2,EPB41L5,ERMAP,KIAA1841,EMP3,RNF19B,FOS,TP53INP2,RHOB,MFAP3L,FAM177A1,RCBTB2,MAP2,RND3,PLK2,NFKBIA,AMMECR1,WDR19,APPL2,SAMD8,NFKBIZ,TMOD2,ZBTB6,CPEB2,CYBRD1,IRF1 |
| 5.471e-03 | -5.21 | V$MTF1_Q4 | MSigDB lists | V$MTF1_Q4 | 235 | 49 | 17758 | 2588 |
MRC2,PPP4R4,ARMCX3,NUAK1,PPM1J,WDTC1,KCTD12,PHLPP1,DOCK11,NFAT5,CYP26A1,SLC9A7,CHPF,MECOM,SAP130,ARTN,PPME1,LHX6,PPP1R16A,ARVCF,DAB2IP,DGKG,CNPY3,FGFR1OP2,DNAI1,SMARCA2,ELK3,PCDH1,BCL9,HMG20B,UBAC1,TMTC2,CLCN2,H2AFV,RNF19B,COL12A1,MAGED2,TMEM50B,H1F0,MYLK,CTNND1,EFNA5,HMGA1,CEP41,CDAN1,SEMA3A,TOB1,PPP2R5D,RPS6KA3 |
| 5.471e-03 | -5.21 | V$GATA1_03 | MSigDB lists | V$GATA1_03 | 235 | 49 | 17758 | 2588 |
LTBP1,PCOLCE,NF2,ENO2,DCAF7,CCM2,WDTC1,GABRG2,NDRG2,RASGRP3,EFNB1,SSX2IP,ZNF385B,NRP2,SYTL2,MECOM,GBX2,WWP2,ADD3,RALGPS2,GNB5,FLRT3,LHX6,ELF5,PPP1R16A,PRKCI,TWIST1,PIM1,ERBB3,PVRL4,HES1,FZD4,DENND1B,SERTAD4,FURIN,TMEM151A,PRRC1,CD40,PITX2,SLC9A6,SPAG7,FAM117A,SP6,SERPINB6,NR3C2,TOB1,FOXA1,CAPN1,EGLN1 |
| 5.473e-03 | -5.21 | human chr9q34 | chromosome location | human chr9q34 | 50 | 12 | 26250 | 2805 |
TSC1,RPL12,TUBB4B,TRAF2,RC3H2,SLC2A6,PPP2R4,SH3GLB2,ABCA2,FAM78A,NCS1,C9orf9 |
| 5.473e-03 | -5.21 | regulation of cysteine-type endopeptidase activity | biological process | GO:2000116 | 224 | 48 | 16441 | 2455 |
CASP3,NKX3-1,RPS6KA1,DAP,TRAF2,SERPINB9,RET,XIAP,BCAP31,TFAP4,CARD8,CTGF,CYR61,CTSC,PAK2,DAPK1,BAX,FNIP1,CDKN1B,RAG1,EGLN3,WNT3A,CDKN2D,F2R,SIRT1,RHOA,AKT1,ACVR1C,PLAUR,CASP9,SLC11A2,CYFIP2,BCL2L13,POR,VCP,FAS,BCL10,CASP7,KIAA0141,HTT,PRDX3,NGFRAP1,ARRB1,GPER1,MAP3K5,IFI6,RPS6KA3,XDH |
| 5.478e-03 | -5.21 | adrenal_cortical_carcinoma | COSMIC cancer mutations | adrenal_cortical_carcinoma | 2342 | 382 | 17775 | 2585 |
DOC2A,HECA,PPP4R4,PNISR,HSPG2,GRIK2,VANGL1,ATP8A1,KLC2,RET,NRG2,LGI3,BAIAP3,CA8,KIF26A,GRM5,PQLC2,DNAH6,STIM1,RGS3,PRICKLE3,IL31RA,STEAP2,PIK3CA,SNX16,ARMCX6,TIAM1,TIPARP,ERAP2,TUBA4A,SMARCA2,KIFC2,SNTB2,F12,COL12A1,ULK2,SGPP1,AHRR,SLC25A4,PTER,GNPTAB,MYLK,PPP2R4,LRIG1,NOD2,TANC2,TRAF5,ANXA11,FRMD4A,SCOC,TMTC3,ITGA6,CALB2,ZNRF3,TTYH3,DNPEP,FRY,SNX18,CD22,PRICKLE4,MEGF8,BDH1,MSH2,DAPK1,CADPS2,ALPK1,CNGA1,PIKFYVE,MOXD1,MYLIP,DGKG,GPR161,EPHX1,DNAI1,GCC2,QSOX1,KLK5,CEP89,MICB,AMER1,ZNF503-AS2,WHSC1,TP53INP2,KDM3A,STK17A,PTPRF,NCOA3,AP1AR,ETS2,HTT,DCK,MATN2,RAET1L,ITPR1,FAM83D,FGD6,CABIN1,GDF11,DRP2,MAP3K5,PER3,SERPINB1,ADAMTS16,DOCK9,TCF25,CAPN12,ST14,ACTR8,BROX,CCDC110,IQGAP1,PKP2,ZNF385B,APPBP2,UHRF1BP1L,MUC16,ST5,XYLT2,DAB2IP,ARL4D,RASGEF1A,RAB27B,OSBPL7,FLOT2,SCN3A,MYO5B,DOCK4,ERMP1,COG2,CAPN6,PLEKHO1,SYNE2,UTRN,TEP1,PRKCQ,ALCAM,ATP10D,EBF2,GIGYF1,NIN,DDOST,INPP4B,PNPLA6,RGS14,ISOC1,PRKAR1A,ARHGEF3,FARP1,NKX3-1,TAOK2,PARP14,ATP9A,ESRP1,MAN1A2,ZNF219,DNAH3,NFAT5,TMCC3,CKAP5,PDIA4,SNTA1,ZFX,OXCT1,PTEN,CENPJ,TUBGCP6,CD9,ATP8B1,ZNF230,CASD1,SLC16A5,NCOA2,PVRL4,ADAMTS2,PDGFC,ARHGEF28,FMN1,TMEM221,GRIN1,CXorf57,PARP4,FURIN,PGBD1,CRTC2,NUCB1,RIN3,PGM2L1,MELK,OCLN,USP16,TLL2,ESYT2,JARID2,UNKL,EXPH5,KIAA1462,FAF2,AGRN,TMEM184B,EPHA4,ARFGEF1,MPP5,KIF2C,HDAC6,ERP29,SPTB,TRIM68,SIPA1L2,CTNNB1,GRHL1,TSPAN6,MKRN3,DDHD2,ABCA2,POF1B,KIF22,ASH2L,MYH14,TLN2,MYRIP,BTBD3,NEB,ZNF462,OLFML2A,TDP1,TRIM8,MCTP1,CELSR2,SYNE3,ACBD3,ITCH,KLK6,ESYT1,IDH1,PTGFRN,VCP,DPYSL3,PLEKHG6,HPSE,MADD,ADIPOR1,SP6,EPB41L4A,CHPT1,RRAGD,ARAP3,USH1C,HJURP,LGALS3,PPP1R12A,ETV5,NCKAP1,SAMD9,DOCK11,AIM1L,RB1,TNS3,KIAA0895,PFKL,FRAS1,KIF13B,SLC30A6,MTMR10,EBF4,PRKCI,FNIP1,SRP54,KNTC1,WNT3A,NCEH1,PLCB2,PCDH1,USP31,FBXO8,ZSCAN12,EIF2AK1,KIAA1109,RNF113A,HEATR5A,BCL2L13,NUBP1,EGFR,NMT2,MUM1L1,PRX,GNAS,NXPH4,ZDBF2,SHROOM2,FBXW5,LMO7,NCKAP5,FOXM1,TP53,CCDC68,CCNL1,MICALL2,EXT2,SYTL2,SS18,ZNF687,ARTN,SETDB2,FRYL,LHX6,FABP6,GYS1,GOT1,RPN2,TMEM64,PDIA6,SULF2,TMTC1,ACO1,ERBB2IP,TMTC2,SNAPC2,DOCK5,FANCE,ARHGAP35,PTPRJ,RTN4RL1,RBL1,SECTM1,TLE1,MAOA,SPTBN5,PLXND1,NDST3,KDELC2,ZC3HC1,BIN1,ANXA3,SORT1,TRAPPC10,ARHGEF11,MACC1,SHPRH,SH3D19,GTF3A,TRMT2B,HMGXB4,SH2D4A,NRP2,SLC9A2,HDAC9,TOP2A,SNX13,CARD8,MAGEE1,LYPD6,BMP7,TOX2,GALNS,KIAA0319,BRD7,TRIM21,ABCD1,HSPA13,IQGAP3,ATP2B1,MYO5A,HMMR,HMGN5,PSMB4,NR4A1,DPP9,MAML2,COL7A1,CAPNS1,FXR2,FNDC3A,TXNDC11,MAP1B,BANK1,FIBCD1,UACA,ZMIZ1,L1CAM,ARHGEF4,NGEF,GOLGB1 |
| 5.480e-03 | -5.21 | negative regulation of cytoplasmic transport | biological process | GO:1903650 | 105 | 26 | 16441 | 2455 |
TXN,ERLEC1,BAG4,NFKBIE,THRA,LITAF,RAB23,PSMD10,BARD1,APC2,SNX12,NOV,SP100,BMP7,CABP1,WWTR1,NFKBIA,UBE2J1,DAB2IP,PKD2,MDFIC,YOD1,MAPK7,PKIA,MDFI,CHP1 |
| 5.483e-03 | -5.21 | adrenal_gland | COSMIC cancer mutations | adrenal_gland | 2723 | 440 | 17775 | 2585 |
DOC2A,HECA,PPP4R4,PNISR,HSPG2,GRIK2,VANGL1,ATP8A1,KLC2,RET,NRG2,LGI3,BAIAP3,CA8,KIF26A,GRM5,CDKN2C,PAK6,PQLC2,DNAH6,STIM1,RGS3,PRICKLE3,IL31RA,STEAP2,PIK3CA,SNX16,SEMA3G,ARMCX6,TIAM1,TIPARP,ERAP2,TUBA4A,SMARCA2,KIFC2,SNTB2,F12,POR,COL12A1,ULK2,SGPP1,AHRR,PIAS3,SLC25A4,PTER,GNPTAB,MYLK,PPP2R4,LRIG1,NOD2,MRPS28,TANC2,TRAF5,ANXA11,FRMD4A,SCOC,TMTC3,ITGA6,CALB2,ZNRF3,TTYH3,DNPEP,FRY,SNX18,CD22,PRICKLE4,MEGF8,ZIC5,BDH1,MSH2,DAPK1,PCYOX1,CADPS2,ALPK1,CACNA1D,CNGA1,PIKFYVE,CTSD,NCAM1,MOXD1,MYLIP,DGKG,GPR161,EPHX1,DNAI1,GFPT1,GCC2,QSOX1,KLK5,CEP89,MICB,AMER1,ZNF503-AS2,WHSC1,KIF20B,TP53INP2,KDM3A,GNA11,STK17A,PTPRF,CACHD1,NCOA3,AP1AR,FNTA,ETS2,HTT,DCK,MATN2,RAET1L,ITPR1,FAM83D,FGD6,CABIN1,GDF11,DRP2,MAP3K5,PER3,SERPINB1,ADAMTS16,DOCK9,TCF25,CAPN12,ST14,ACTR8,BROX,CCDC110,IQGAP1,PKP2,PRKACA,FLT3,GNB2,ZNF385B,APPBP2,UHRF1BP1L,RBM23,MUC16,ST5,CDH1,XYLT2,DAB2IP,ARL4D,RASGEF1A,RAB27B,OSBPL7,FLOT2,SCN3A,MYO5B,DOCK4,ERMP1,COG2,FZD4,CAPN6,PLEKHO1,SYNE2,UTRN,TEP1,PRKCQ,ALCAM,ATP10D,EBF2,GIGYF1,NIN,EPHA10,IRS2,DDOST,INPP4B,PNPLA6,PPP1CB,RGS14,ARNT,ISOC1,PRKAR1A,ARHGEF3,FARP1,TAOK2,NKX3-1,PARP14,ATP9A,ESRP1,MAN1A2,ZNF219,DNAH3,NFAT5,TMCC3,CKAP5,PDIA4,SNTA1,ZFX,OXCT1,PTEN,CENPJ,TUBGCP6,CD9,ATP8B1,ZNF230,ERBB3,CASD1,SLC16A5,NCOA2,PVRL4,ADAMTS2,PDGFC,ARHGEF28,LONRF3,FMN1,TMEM221,PIK3R1,GRIN1,CXorf57,PARP4,FURIN,PGBD1,CRTC2,NUCB1,FGFR2,RIN3,PPM1H,PGM2L1,MELK,OCLN,USP16,TLL2,ESYT2,JARID2,EXPH5,UNKL,FAF2,KIAA1462,AGRN,TMEM184B,EPHA4,ARFGEF1,MPP5,KIF2C,HDAC6,ERP29,TRIM68,SPTB,SIPA1L2,CTNNB1,GRHL1,MKRN3,TSPAN6,PAPSS1,DDHD2,ABCA2,POF1B,KIF22,ASH2L,NTN4,MYH14,TLN2,MYRIP,BTBD3,NEB,ZNF462,OLFML2A,TDP1,TRIM8,MCTP1,CELSR2,SYNE3,ACBD3,ITCH,KLK6,ESYT1,IDH1,PTGFRN,VCP,DPYSL3,PLEKHG6,HPSE,MADD,ADIPOR1,SP6,EPB41L4A,CHPT1,RRAGD,ARAP3,USH1C,HJURP,LGALS3,PPP1R12A,ETV5,NCKAP1,SAMD9,DOCK11,ANO1,TNS3,RB1,AIM1L,KIAA0895,VASP,PFKL,FRAS1,KIF13B,SLC30A6,MTMR10,EBF4,PRKCI,FNIP1,SRP54,KNTC1,ZRANB1,NCEH1,WNT3A,PLCB2,PCDH1,USP31,FBXO8,ZSCAN12,EIF2AK1,KIAA1109,SCRIB,RNF113A,HEATR5A,BCL2L13,NUBP1,EGFR,NMT2,MUM1L1,PRX,GNAS,PRPS2,NXPH4,CTSA,ZDBF2,SHROOM2,JAK3,FBXW5,LMO7,NCKAP5,NF2,FOXM1,TP53,CCDC68,ERBB2,CCNL1,MICALL2,EXT2,SYTL2,CYP26A1,SS18,ZNF687,ARTN,SETDB2,FRYL,FABP6,LHX6,SMO,GYS1,GOT1,RPN2,STEAP3,TMEM64,PDIA6,HSPA2,SULF2,TMTC1,AKT1,ACO1,ERBB2IP,TMTC2,SNAPC2,FANCE,DOCK5,ARHGAP35,ZNF628,ATP1A1,PTPRJ,RTN4RL1,RBL1,SECTM1,TLE1,MAOA,SPTBN5,PLXND1,AKNA,AIFM3,ABCA1,NDST3,KDELC2,ZC3HC1,BIN1,ANXA3,SORT1,ENO2,TRAPPC10,ARHGEF11,MACC1,SH3D19,SHPRH,GTF3A,TRMT2B,LBR,HMGXB4,SLC9A2,SH2D4A,NRP2,HDAC9,TOP2A,SNX13,CARD8,MAGEE1,LYPD6,BMP7,TOX2,GALNS,KIAA0319,BRD7,TRIM21,ABCD1,HSPA13,IQGAP3,MYO5A,ATP2B1,DLGAP1,HMMR,HMGN5,PSMB4,NR4A1,DPP9,MAML2,COL7A1,CAPNS1,FXR2,FNDC3A,TXNDC11,MAP1B,BANK1,FAT4,SCG2,FIBCD1,CSGALNACT1,UACA,ZMIZ1,L1CAM,ARHGEF4,NGEF,GOLGB1 |
| 5.497e-03 | -5.20 | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 184 | 40 | 17758 | 2588 |
GAA,MTM1,SORT1,TRIM24,MPZL1,TBC1D1,BTN3A1,CHAC2,ITPR2,CD46,DOPEY2,ACAP2,METTL7A,PHKA2,SLC35A1,RNF169,MAP3K3,GCA,SEC23A,PTPN18,KIAA0040,NRBF2,PYGL,STX3,RASA1,CMTM7,USP6,ZMPSTE24,SGPP1,TSC1,CARHSP1,STK38,DBI,SECTM1,GRAMD1C,HIPK3,GAB1,CAPN1,RPS6KA3,CD33 |
| 5.497e-03 | -5.20 | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | 184 | 40 | 17758 | 2588 |
CMAS,MRPL44,APOO,PSMD10,NDUFA4,DNAJB9,EPDR1,PCNA,UBE2T,TM9SF2,TSPAN6,ALG13,BAX,MSH2,HSPA13,MANF,RNASEH2A,CITED2,PDIA6,PSMA5,TMX1,SNX7,SYPL1,RHOA,CTNNAL1,UXT,PBK,VAMP3,C1GALT1C1,SLC25A5,FBXO10,CDK1,SLC44A3,PRDX4,ATP1A1,DBI,CAB39,PPP2R3C,NUP37,CCNB2 |
| 5.497e-03 | -5.20 | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | 184 | 40 | 17758 | 2588 |
LASP1,SLC2A4,SORBS1,HSPG2,EPAS1,PEX6,SOD2,BLCAP,ETS1,TSPAN17,ECI1,SLC25A35,APLP2,WEE1,CYR61,DNM2,GYS1,STEAP3,GM2A,AKT1,ACVR1C,ADCK3,KIF1C,TNS1,ZFAND5,PLIN5,MAPK8IP1,EDNRA,SFXN1,CARHSP1,CD8A,NIPSNAP3A,BMP1,FAM195A,FHL1,PER3,RPS6KA3,DLAT,EHD1,DMPK |
| 5.501e-03 | -5.20 | nucleotide kinase activity | molecular function | GO:0019201 | 24 | 9 | 16491 | 2452 |
CASK,AK7,MPP1,DLG1,MPP2,AK4,AK3,DLG3,CMPK2 |
| 5.503e-03 | -5.20 | copper ion import | biological process | GO:0015677 | 9 | 5 | 16441 | 2455 |
SLC11A2,STEAP3,STEAP1,ATP7B,STEAP2 |
| 5.503e-03 | -5.20 | regulation of helicase activity | biological process | GO:0051095 | 9 | 5 | 16441 | 2455 |
SIRT1,IFIT1,MSH6,MSH2,TP53 |
| 5.503e-03 | -5.20 | tongue morphogenesis | biological process | GO:0043587 | 9 | 5 | 16441 | 2455 |
HDAC1,CTNNB1,TBX1,SIX4,HOXC13 |
| 5.503e-03 | -5.20 | positive regulation of metaphase/anaphase transition of cell cycle | biological process | GO:1902101 | 9 | 5 | 16441 | 2455 |
PLK1,RB1,DLGAP5,PTEN,ESPL1 |
| 5.503e-03 | -5.20 | protein maturation by protein folding | biological process | GO:0022417 | 9 | 5 | 16441 | 2455 |
CALR,WFS1,AIP,ERO1A,PRDX4 |
| 5.503e-03 | -5.20 | positive regulation of mitotic sister chromatid separation | biological process | GO:1901970 | 9 | 5 | 16441 | 2455 |
PLK1,RB1,DLGAP5,PTEN,ESPL1 |
| 5.503e-03 | -5.20 | enamel mineralization | biological process | GO:0070166 | 9 | 5 | 16441 | 2455 |
CNNM4,FAM20C,STIM1,TBX1,PPARA |
| 5.503e-03 | -5.20 | positive regulation of mitotic metaphase/anaphase transition | biological process | GO:0045842 | 9 | 5 | 16441 | 2455 |
PLK1,RB1,DLGAP5,PTEN,ESPL1 |
| 5.503e-03 | -5.20 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent | biological process | GO:0002480 | 9 | 5 | 16441 | 2455 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 5.511e-03 | -5.20 | PRKCQ (protein kinase C, theta) | protein interactions | 5588 | 39 | 13 | 16036 | 2547 |
CASP3,FYN,AKT1,HABP4,SELL,RASGRP3,PRKCQ,STK39,MAP3K7,CBL,GRM5,DEF6,BCL10 |
| 5.535e-03 | -5.20 | MAPK9 (mitogen-activated protein kinase 9) | protein interactions | 5601 | 104 | 27 | 16036 | 2547 |
CASP3,ELK3,SHMT1,AKT1,TRAF2,TP53,FTH1,DUSP4,PKN1,ELK1,CDC25C,MAPK8IP1,EGFR,HDAC9,BCL10,CYHR1,RB1,CTNNB1,STK26,SERPINB5,DUSP10,ARRB1,HDAC1,WDR62,CTBP1,TOB1,DUSP1 |
| 5.544e-03 | -5.20 | Rho protein signal transduction | biological process | GO:0007266 | 60 | 17 | 16441 | 2455 |
ARHGEF3,RHOA,CTNNAL1,ARHGEF11,ADGRG1,STRADB,ARHGDIB,RHOB,EPS8L2,PAK6,MCF2L,LIMK1,PAK2,BCL6,TAX1BP3,NTN1,ARHGAP4 |
| 5.545e-03 | -5.19 | EF-hand_7 | pfam domains | PF13499 | 89 | 23 | 16629 | 2504 |
SLC25A24,KCNIP3,CALM1,CALB2,CALM3,EFHD2,PLS1,NUCB2,MCFD2,MYL12A,HPCAL4,PPP2R3A,NCS1,LCP1,PLS3,CALM2,DUOX1,NUCB1,PLCH1,CABP1,CGREF1,DGKG,CHP1 |
| 5.550e-03 | -5.19 | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | 97 | 24 | 17758 | 2588 |
AKT1,NR4A1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,PHLPP1,ITPR3,PRKACA,CDK1,FGF19,CALM2,PLCG1,ADRBK1,PTEN,FGFR2,FGF18,PIK3CA,CDKN1B,GAB1,FRS3,PRKAR1A |
| 5.566e-03 | -5.19 | TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | TRANSCRIPTION_FACTOR_ACTIVITY | 346 | 68 | 17758 | 2588 |
PAX6,TCF25,EPAS1,THRA,TSC22D3,PTTG1,TP53,GATA3,EGR3,PHF1,MXD1,TP73,HSF2,LMO4,PHTF1,LHX6,ARNT2,NFKB2,TAF5,DRAP1,NFE2L1,TFAP2C,SNAPC2,CBL,NFIX,HSF4,KLF12,TBX1,STAT6,ZNF367,STAT1,HDAC1,KLF11,NR3C2,LZTS1,ARNT,NR2C2,ETV5,ZNF219,NFAT5,SCML1,GBX2,MECOM,TFAP4,RB1,GATA2,KLF9,CITED2,NFE2L3,POU6F1,TGIF1,NR3C1,TCFL5,STAT4,MYBL2,RUNX3,ELK1,NFIB,FOXL1,SOX13,FOXD2,PITX2,E2F1,HMGA1,USF2,AHR,FOXA1,KLF7 |
| 5.575e-03 | -5.19 | ATF2 (activating transcription factor 2) | protein interactions | 1386 | 206 | 47 | 16036 | 2547 |
ANXA3,HSP90B1,S100A11,SLC25A13,PDIA3,OAT,GSTP1,ERP29,S100A2,ETS1,PCBP1,GNB2,BCAP31,PDIA4,CALR,CCND1,RB1,SS18,PCNA,CTNNB1,P4HB,GTF2F2,H2AFY,MAPK11,TACSTD2,AHCY,TAGLN2,CTTN,MYDGF,TMX1,PPIF,THRB,ERO1A,PKM,FOS,ARF4,RAB2B,SFXN1,ATP1A1,DDOST,CCDC6,APMAP,TLE1,CTNND1,MAPK13,HMGA1,HSPB1 |
| 5.577e-03 | -5.19 | phosphatidylinositol bisphosphate phosphatase activity | molecular function | GO:0034593 | 20 | 8 | 16491 | 2452 |
MTM1,INPP5E,PTEN,OCRL,TMEM55B,INPP4B,PIKFYVE,EPM2A |
| 5.596e-03 | -5.19 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP | 173 | 38 | 17758 | 2588 |
KLF2,ATP8A1,UBASH3B,NDRG1,TSC22D3,ITGA6,XYLT1,EPHA4,HABP4,PDCL,ASAH1,TRIB2,DNAJB9,CAPN2,RALGPS2,MGAT4A,AIM1,FBXO7,PASK,SORL1,SGK1,CITED2,MYLIP,C9orf72,DUSP1,GABARAPL1,RASGRP2,TXK,IRS2,PTGS2,GNPTAB,PELI2,WDR19,FAM117A,YOD1,NR4A2,NFKBIZ,PCSK5 |
| 5.601e-03 | -5.18 | TRAF3 (TNF receptor-associated factor 3) | protein interactions | 7187 | 109 | 28 | 16036 | 2547 |
OTUD5,CASP3,TNIP1,RIPK2,IL15,NLRX1,TRAF2,DCAF7,GRIN1,IFIT3,CD40,TNFRSF19,OPTN,FAS,NGFRAP1,TRAF3IP1,OTUB2,GRIN2D,TNFRSF12A,TNFRSF18,MAP3K5,TFG,TRAF5,MYT1,SYK,TMEM173,ABCC1,IRF1 |
| 5.660e-03 | -5.17 | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | MSigDB lists | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | 113 | 27 | 17758 | 2588 |
LASP1,GCC2,IFITM3,PARP14,NR4A1,DAP,PNPLA2,SDC4,PLS1,TRIB2,HLA-A,MECOM,SOCS3,GALNT3,PROM1,AGPAT2,GNB5,GPRC5B,KCNK1,RGS3,SETD3,ELF5,FOSB,TSPAN18,DAPK1,TNFRSF12A,ECE1 |
| 5.661e-03 | -5.17 | regulation of alpha-beta T cell proliferation | biological process | GO:0046640 | 24 | 9 | 16441 | 2455 |
CD55,RIPK2,ITCH,HLA-E,IL18,C10orf54,SYK,HLA-A,IRF1 |
| 5.661e-03 | -5.17 | establishment of mitotic spindle localization | biological process | GO:0040001 | 24 | 9 | 16441 | 2455 |
CENPA,HTT,NDC80,NUSAP1,GPSM2,SPDL1,NDE1,SPRY2,ESPL1 |
| 5.663e-03 | -5.17 | KIM_WT1_TARGETS_8HR_UP | MSigDB lists | KIM_WT1_TARGETS_8HR_UP | 162 | 36 | 17758 | 2588 |
GOLIM4,ENO2,ATP9A,SOX9,STRN4,SLC20A1,SIRPA,BTG3,ZYX,DOK4,IL6ST,WWP1,PIK3CD,PIM1,ULBP2,IL1RAP,ATP2B1,TUBA4A,METAP2,PDGFC,PLAUR,PLEKHO1,TNS1,SWAP70,TIMP3,SERTAD2,AREG,CSF1,WWTR1,PIAS2,PLXND1,HMGA1,GEM,ZMIZ1,ST3GAL1,MAFF |
| 5.667e-03 | -5.17 | BROWNE_HCMV_INFECTION_24HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_UP | 140 | 32 | 17758 | 2588 |
TRIP10,ATP8A1,ETV5,SPR,KBTBD11,MERTK,ICAM1,PDIA4,NEO1,EPCAM,PAK2,ALDH1A3,MAP3K9,IL17RA,NPTXR,RASGRP1,CAMK2G,MED22,TESK1,AK4,PRIM1,CD83,SLC25A4,PSMD3,TRAF3IP1,NFKBIA,NR4A3,FZD5,F2RL1,IFI6,FOXA1,OCLN |
| 5.667e-03 | -5.17 | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | 140 | 32 | 17758 | 2588 |
PRKAA2,CEP70,ALDH6A1,AASS,C5orf30,COX6C,OAT,TSPAN7,SCML1,SLC25A36,APLP2,OXCT1,IGF1R,BMP7,SRR,ECI2,KLF9,GAD1,CTH,THRB,ZFAND5,CYB5A,GABARAPL1,GNAS,UAP1,FA2H,KIAA0141,PRDX3,ITPR1,DHTKD1,ISOC1,DLAT |
| 5.675e-03 | -5.17 | CHIBA_RESPONSE_TO_TSA | MSigDB lists | CHIBA_RESPONSE_TO_TSA | 47 | 14 | 17758 | 2588 |
GRN,RHOA,CTGF,CYR61,IFITM3,H1F0,DHRS2,TMEM55B,SDC4,STAT1,PRKRA,RHOB,DUSP1,OPTN |
| 5.675e-03 | -5.17 | OLSSON_E2F3_TARGETS_DN | MSigDB lists | OLSSON_E2F3_TARGETS_DN | 47 | 14 | 17758 | 2588 |
PLK1,KRT80,PCNA,TIMP3,CCNA2,NFKBIA,PTTG1,MYBL2,CD9,TAF6L,MAL2,UBE2C,CDK1,LBR |
| 5.675e-03 | -5.17 | NADERI_BREAST_CANCER_PROGNOSIS_UP | MSigDB lists | NADERI_BREAST_CANCER_PROGNOSIS_UP | 47 | 14 | 17758 | 2588 |
KIF20A,TRIM24,FA2H,ASPM,CDCA5,ATP2C2,PTTG1,NDC80,MYBL2,CDCA8,BUB1,RACGAP1,CENPN,MELK |
| 5.684e-03 | -5.17 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP | 224 | 47 | 17758 | 2588 |
ACACB,TNRC6C,PNISR,CEP70,FRMD4A,ETV5,GMCL1,VARS2,GTF3A,ISYNA1,LBR,H1FX,NEO1,MECOM,B3GALNT1,UBE2T,LMO4,FAM13B,SCARA3,PHKA2,SPRY2,MSH6,EEF1D,GPR161,SMC4,SEPHS1,GFPT1,OPLAH,ALDH2,PSMB4,PAPD7,FZD7,ARHGEF26,MAN2A2,GNAS,SHROOM3,ABHD12,ZNF704,AGBL5,IARS2,FAM117A,MDH1,GLCCI1,CHPT1,TRAF5,LIFR,PHC1 |
| 5.684e-03 | -5.17 | V$SOX9_B1 | MSigDB lists | V$SOX9_B1 | 224 | 47 | 17758 | 2588 |
HSPG2,HOXB7,KLHL13,TSC22D3,DGKA,TRIB2,APBA1,SYTL2,NEO1,HDAC9,CCDC92,TOP2A,RCN1,WEE1,CTNNB1,SH3BP1,DPYSL2,RGS3,FLRT3,LHX6,KLF3,CDKN1B,NCAM1,MYT1,SEPHS1,MAP3K3,DPYSL5,DOCK4,TRIM8,CASK,MBP,FBLN5,NR4A1,KIF20B,NFIB,G2E3,ARF4,NFIX,ARHGEF19,FGFR2,PELI2,C1orf21,E2F1,TLE1,EFNA1,ZNF502,PHC1 |
| 5.686e-03 | -5.17 | CoA carboxylase activity | molecular function | GO:0016421 | 6 | 4 | 16491 | 2452 |
PCCB,ACACB,MCCC2,MCCC1 |
| 5.686e-03 | -5.17 | insulin binding | molecular function | GO:0043559 | 6 | 4 | 16491 | 2452 |
IDE,INSR,IGF1R,PIK3R1 |
| 5.696e-03 | -5.17 | Crosslinking of collagen fibrils | REACTOME pathways | R-HSA-2243919 | 9 | 5 | 8202 | 1235 |
LOXL2,PCOLCE,LOXL1,BMP1,TLL2 |
| 5.696e-03 | -5.17 | Transport of nucleotide sugars | REACTOME pathways | R-HSA-727802 | 9 | 5 | 8202 | 1235 |
SLC35C1,SLC35D2,SLC35A1,SLC35B3,SLC35B4 |
| 5.696e-03 | -5.17 | Elevation of cytosolic Ca2+ levels | REACTOME pathways | R-HSA-139853 | 9 | 5 | 8202 | 1235 |
ITPR2,ITPR3,TRPC3,STIM1,ITPR1 |
| 5.696e-03 | -5.17 | RHO GTPases Activate Rhotekin and Rhophilins | REACTOME pathways | R-HSA-5666185 | 9 | 5 | 8202 | 1235 |
RHPN2,TAX1BP3,RHOA,RHOB,RHPN1 |
| 5.701e-03 | -5.17 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP | 190 | 41 | 17758 | 2588 |
UGP2,CCM2,SDC4,OSR2,CHST2,RND1,SGPL1,VASP,ITGB8,PTEN,PIK3AP1,SNX18,FJX1,GTF2F2,PIK3CD,NFE2L3,TRIM8,TNIP1,PLSCR1,CD40,RNF19B,STK17B,PSMA4,MYL12A,DCP2,SOCS3,NIN,MYPOP,PTPRJ,HNRNPH2,STK38,RAP2C,SLC2A6,ARRB1,NFKBIZ,CTNND1,EFNA1,IFIH1,KLF7,IRF1,EHD1 |
| 5.701e-03 | -5.17 | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDM_DN | 190 | 41 | 17758 | 2588 |
LZTFL1,IL15RA,PARP14,DHPS,RASA2,SERPINB9,GABRG2,MRAS,CYP39A1,REPS1,RAD23A,ADRBK1,TIMP1,RNF128,MITF,SRP54,TWIST1,TAGLN2,CTTN,CITED2,TIPARP,C9orf72,CPD,RIPK2,NUB1,CCBL2,SPTLC2,MAP3K6,PSMA4,CASP4,LEPR,IRX3,SFXN1,PVRL2,HOXA9,NFKBIA,DGAT2,TDRD7,PPP1CB,AHR,MAFF |
| 5.701e-03 | -5.17 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_DN | 190 | 41 | 17758 | 2588 |
ANXA3,TTC39B,HOXB7,LFNG,JKAMP,UBASH3B,ADCK5,DHRS3,GNB2,IL18R1,TTYH3,CDH1,RABEP2,CTSC,RINL,CAPG,TFAP2A,SGK1,NTN4,PACSIN1,SULF2,SUN2,TGIF1,CXXC5,MMD,B9D2,PIK3R1,DIAPH2,RUNX3,ATP1B1,CD40,NMT2,KLHL2,CD8A,BTG1,LDLRAP1,RAB11FIP2,PVRL2,LRIG1,F2RL1,MYL12B |
| 5.701e-03 | -5.17 | GSE17721_0.5H_VS_4H_LPS_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_4H_LPS_BMDM_DN | 190 | 41 | 17758 | 2588 |
LZTFL1,TCF25,RUNX2,GRHL2,PARP14,KLHL13,FRMD6,IQGAP1,SERPINB9,IL18,TIMP1,ARTN,LMO4,LHX6,SLC44A1,UBE2J1,CD70,PIKFYVE,LOXL1,PTPRE,IL10RB,MGAT5,HP1BP3,GCA,PMPCB,SLC5A11,MOSPD2,SLC39A8,MPP1,DBR1,TANC1,SPTLC2,EGFR,ETS2,RBM47,FAAH,PPP1CB,PRKCDBP,RBM43,TRAF5,HOXC13 |
| 5.701e-03 | -5.17 | iron ion homeostasis | biological process | GO:0055072 | 95 | 24 | 16441 | 2455 |
SOD1,MFI2,EPAS1,ABCG2,ACO1,ATP6V1E2,TTC7A,EIF2AK1,FTH1,SLC11A2,NUBP1,SFXN5,STEAP1,NEO1,FECH,SFXN1,ATP6V0B,HTT,SLC46A1,STEAP2,STEAP3,ATP6V1C1,NDFIP1,CYBRD1 |
| 5.707e-03 | -5.17 | regulation of protein localization to cell periphery | biological process | GO:1904375 | 65 | 18 | 16441 | 2455 |
LZTFL1,SORBS1,AKT1,PIK3R1,EZR,PLS1,BCL2L1,ARHGEF16,STX3,KIF5B,LDLRAP1,ITGA3,PPP2R5A,PRKCI,DLG1,GPER1,ARF6,TMBIM1 |
| 5.707e-03 | -5.17 | regulation of protein localization to plasma membrane | biological process | GO:1903076 | 65 | 18 | 16441 | 2455 |
LZTFL1,SORBS1,AKT1,PIK3R1,EZR,PLS1,BCL2L1,ARHGEF16,STX3,KIF5B,LDLRAP1,ITGA3,PPP2R5A,PRKCI,DLG1,GPER1,ARF6,TMBIM1 |
| 5.708e-03 | -5.17 | HSIAO_HOUSEKEEPING_GENES | MSigDB lists | HSIAO_HOUSEKEEPING_GENES | 382 | 74 | 17758 | 2588 |
LAMP1,CCNI,PAX6,TXN,IQGAP1,CAST,NDRG1,FTH1,PSME1,MORF4L2,MGST2,BCAP31,APLP2,CTNNB1,ZFP36,RPN2,CTDSP2,GPX4,SOD1,SEC61B,DSTN,EZR,ARHGDIB,SLC25A5,ARF4,FYN,MPRIP,HDAC1,SERPINB6,LTA4H,HSPB1,PSMC1,ANXA11,LASP1,LGALS3,DHPS,CD63,HLA-E,PSMD7,AES,NDUFA4,COX6C,GSTP1,COX7A2,HLA-A,CAPN2,CES2,IRAK1,RPL39,CST3,TMBIM6,TAGLN2,PIM1,NDUFA12,EEF1D,DUSP1,RHOA,PSMB4,GUSB,CAPNS1,NPC2,ILK,NFIB,FAS,GNAS,FUCA1,FNTA,RPL12,NFKBIA,MDH1,FHL1,ARPC2,CD81,UBE2C |
| 5.711e-03 | -5.17 | positive regulation of cellular biosynthetic process | biological process | GO:0031328 | 1763 | 300 | 16441 | 2455 |
ACVR1,TRIM24,LGR4,TRIM5,DNAJC3,HEXB,RET,GATA3,MORF4L2,CAMK1D,TP73,NPM2,CALM2,HELZ2,IL31RA,FOSB,DNM2,IRF2,NEK4,SMARCA2,TNIP1,TFAP2C,AURKB,LDB2,SAV1,POR,ARF4,AHRR,MID1IP1,AREG,TBX1,NOD2,HDAC1,RNASEL,HSPB1,TRAF5,F2RL1,E2F8,HOXC13,DDX58,KLF2,CDKN1C,ITGA6,SOX9,PSIP1,LMNA,MECOM,ELF3,TFAP4,CALR,CYR61,NEK2,MYDGF,MAPK7,NUP85,GPR161,SALL4,STAT4,CALM1,PYM1,FHL2,MYBL2,CALCRL,ELK1,ILK,TP53INP2,KDM3A,NFIB,PLIN5,NCOA3,SERTAD2,ETS2,SETD3,PIAS2,NR4A2,RPS6KA3,TMEM173,IRF1,ARMCX3,GRHL2,THRA,RPS6KA1,CCNA2,CDH1,SP100,DAB2IP,ETV4,MED30,PSRC1,RIPK2,FZD4,FOXJ2,PRKCQ,PXYLP1,PYGO1,GTF2A2,EBF2,FZD7,NFIX,IRS2,WFS1,WWTR1,STAT1,KLF5,NRG1,ARNT,ATMIN,NKX3-1,CKAP2,TRAF2,PBX3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,E2F7,IRAK1,PTEN,MCF2L,CST3,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,PDGFC,CASK,PLSCR1,BCL9,TEF,PIK3R1,EIF5A2,GRIN1,YES1,FOS,ABLIM2,TXK,GPLD1,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,NR1D2,ACVRL1,NR4A3,GPER1,HMGA1,FZD5,OSR1,CD81,USF2,SHOX2,FOXA1,USP16,RGMA,CCNC,EPAS1,AGRN,ARFGEF1,PDGFB,TFAP2E,EPCAM,HSF2,PCNA,CTNNB1,GRHL1,NPNT,PSMC2,ELF5,PASK,MITF,ASH2L,ARNT2,MYBL1,ZNF462,THRB,PCGF5,TRIM8,CITED4,ASXL1,NFE2L1,EAF2,VCP,EDNRA,SEC14L2,MDK,KLF12,MAFF,PSMC1,NR2C2,RUNX2,PPP1R12A,ETV5,CALM3,BMP2,RB1,IGF1R,GATA2,PRKCI,EBF4,MDFIC,WNT3A,ELK3,RGMB,EGFR,GNAS,MAPKAPK2,ONECUT1,INSR,PLPP3,NFKBIA,NLRC5,RARG,RAD21,DRD1,KLF7,PAX6,SORBS1,UPF3B,IL15,FOXM1,TP53,ERBB2,CCNL1,OSR2,LPIN3,PDGFA,SS18,LMO4,SMO,CDH3,TWIST1,ZBTB49,NOTCH3,NFKB2,F2R,DVL2,UPF3A,CTH,CHP1,SOAT1,SIRT1,TIMP2,AKT1,TCEB2,SERTAD3,CD40,JADE1,HSF4,PTGS2,RBL1,STAT6,IRF7,AKNA,ABCA1,CNEP1R1,GLIS3,ANXA3,PINK1,TAB3,ARHGEF11,GNAL,HMGN3,TGFBR1,PARM1,GBX2,IRF2BPL,TOP2A,BMP7,TOX2,GTF2F2,TFAP2A,BRD7,TRIM21,SYK,NFE2L3,P2RX4,HES1,RHOA,DCAF6,WNT10B,HMGN5,NR3C1,NR4A1,RGCC,PPARA,MAML2,RUNX3,MPV17L2,BCL10,DDAH1,E2F1,ARRB1,PKD2,ZMIZ1,SOX8,AHR |
| 5.718e-03 | -5.16 | positive regulation of dephosphorylation | biological process | GO:0035306 | 46 | 14 | 16441 | 2455 |
CALM2,BMP2,PINK1,ADORA1,PPP2R5A,PPP1R12A,NPNT,CALM1,PPP2R4,CALM3,CDCA2,SLC39A10,CNEP1R1,GPLD1 |
| 5.720e-03 | -5.16 | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 6295 | 973 | 17775 | 2585 |
DOC2A,HECA,ACACB,TRIM24,ADD1,IL15RA,FAM160B1,IBTK,GRIK2,AASS,DNAJC3,HEXB,RET,MMADHC,DHX8,FAM102B,CNTROB,DPP8,BARD1,FAM46C,SPSB1,CARD10,ZNF275,CDKN2C,NAPG,PHYHIP,ZYX,PQLC2,RGS12,TGFBR3,CYP2S1,KLF3,TUBG1,SEMA3G,ACOX2,PPP1CA,TINAGL1,RNF26,WBP4,TIAM1,IL10RB,MGAT5,ODF2L,ERAP2,CCDC74A,NWD1,SPEF2,SMARCA2,LOXL2,F12,MYOM1,PNKD,CYP4F3,COL12A1,ABR,SLC44A3,PLCG1,WDR11,DNM1L,ANKRD6,ATP7B,LIMK1,MYLK,TRAF3IP1,FAM114A1,NOD2,MAP3K11,AGFG2,MRPS28,RNASEL,RELL1,STARD13,PDPR,GAB1,ANXA11,SCN5A,TMTC3,CYP2J2,ITGA6,STRN4,RAB23,ARHGEF35,MERTK,HPCAL4,LMNA,RABGGTA,TFAP4,FLII,DNPEP,FRY,CD22,RIMS3,MEGF8,NEK2,MAPK7,NCAM1,MOXD1,DGKG,NUP85,MCCC2,EPHX1,NAGPA,HPS3,SLC37A1,KIF20A,FHL2,NPHP3,TP53INP2,SPTLC2,DPYSL4,DHX32,PTPRF,CACHD1,NCOA3,FNTA,SLC4A4,MTFMT,HTT,SETD3,ITPR1,S100A5,DGAT2,CLMN,DYSF,NDE1,TRPC3,TMEM173,RUSC1,XDH,DOCK9,WDR63,ARHGAP11A,NQO1,ACTR8,PKP2,PRSS22,NUF2,IL13RA1,GRK6,FAM91A1,APC2,REPS1,UHRF1BP1L,RBM23,MUC16,ST5,SCNN1A,CDH1,DACT1,RASGEF1A,LRP11,MYT1,RNF169,SCN3A,ENPP4,SNX8,COL6A2,ERMP1,APOBEC3D,PTPN9,SYNE2,HTATIP2,CDCA2,XRCC6BP1,ZNF618,GIGYF1,PEX5,CCNB3,SHROOM3,WFS1,AXL,WWTR1,INPP4B,PLEKHG1,RGS14,ARNT,MAPK12,CTHRC1,FARP1,HSP90B1,TNRC6C,TAOK2,FAM189A2,ESRP1,BACE1,CCM2,OSGIN2,BTN3A1,CTSZ,PKN1,PLPPR4,NFAT5,BEX2,NEO1,CAPN2,DTX3L,SLC25A45,ADD3,PDCD10,FUT2,ITGB8,IGSF9,ARSG,KCNK5,GPC3,MGAT4A,TMEM62,CST3,TUBGCP6,FAM20B,KLC3,ADAM15,WWP1,ZNF230,AK3,RAG1,SGCB,TMX1,PARP9,AMOTL2,PVRL4,ADAMTS2,CTNNAL1,TACC1,RAPGEF2,PIK3R1,ELOVL3,MRS2,CXorf57,PLEKHA7,C4orf27,ABLIM2,CNTNAP1,GALNT3,KIAA0141,ATXN7L3,CCDC6,ACVRL1,SLC35B3,ARFGAP3,CENPE,FHL1,NUP37,CD81,DCBLD1,FOXA1,PHC1,TLL2,TMEM131,CCNI,ILDR1,KIAA1462,AGRN,EPHA4,CUL4B,ARFGEF1,NDC80,MCCC1,TEX2,NENF,MGAT5B,ITPR2,HDAC6,SPTB,FANCI,SUSD2,CPNE2,ENTPD4,NUP210,CTNNB1,RABEP2,MKRN3,IL6ST,PAPSS1,DDHD2,TMEM143,ABCA2,DUSP10,RGS5,ANO4,NEB,S100A13,ZNF462,PLK1,PTPN18,MARK1,CELSR2,STAU2,ARFRP1,ESYT1,ANLN,IDH1,CLCN2,LHFPL2,DZIP1L,OPTN,TNS4,PLCH1,HS6ST1,MSL1,KLF12,MAP2,WIPI1,DOLPP1,RAB11FIP1,ARRDC1,KLF11,PIK3C2B,GLCCI1,PRKAA2,RUNX2,USH1C,HJURP,DNAJB2,ASAH1,NCKAP1,DOCK11,FBLN1,RSAD1,IL18R1,ANO1,SSX2IP,MYO5C,B4GALNT1,TNS3,RB1,VASP,DAZAP1,IGF1R,FRAS1,KIF13B,AHCY,FAR2,WNT3A,TMEM8A,MPHOSPH9,PSMA5,ABCC1,CHSY3,WDR72,USP31,BTNL9,PRX,NMT2,C18orf8,MOSPD3,H1F0,COL13A1,PHLPP2,ITGA7,NLRC5,LTBP2,ZDBF2,ATP1B3,CDAN1,CCNB2,RAD21,UPF3B,FOXM1,TMX4,DGKA,TP53,RHPN2,ERBB2,ZNF28,SLC7A2,FAM198B,LPIN3,SYTL2,PER2,RAD23A,IER3,TTC21B,SRPX,WDR44,TACC2,PLCG2,BCL6,GLB1L2,ESPN,NOTCH3,OAS3,MINPP1,SCN2A,CTDSP2,SULF2,SIRT1,TMTC1,AKT1,ACO1,C3orf33,MYL12A,DAG1,ATP13A2,DNAJC10,ZNF628,DUOX1,IDE,RTN4RL1,PTPRJ,PAFAH1B3,RBL1,ADAMTS14,XRCC3,ARHGAP4,AIFM3,CMTM4,MAN2B2,BIN1,PINK1,DYRK3,PACSIN2,GOLIM4,CDH22,CPEB4,CD63,TAB3,KLHL13,MACC1,RUSC2,SCD5,MCTP2,ERI2,ERCC6L,GTF3A,CHAC2,JAG2,CRABP2,PARM1,VPS26A,IL22RA1,SLC9A2,PPP2R3A,NRP2,M6PR,CD109,FOXP2,CEP97,CDK16,MAGEE1,IL17RA,TRIM21,BUB1,ALDH7A1,HMGCL,KLF9,CAMK2G,TLE6,FAM134C,ATP2B1,LRRC24,NFE2L3,HMMR,DLGAP1,FBLN5,GUSB,AMFR,PPARA,DPP9,MAML2,TRIM35,COL7A1,AKAP3,RNPEP,BCAR1,TXNDC11,MAPK8IP1,BSDC1,PRDX4,BCL10,USP6,FUCA1,DDAH1,BANK1,SERPINA1,FAT4,TWSG1,ZNF214,CDCA7L,ACADM,TBC1D4,HIPK3,GOLGB1,DIS3L,FAM171B,GAA,LGR4,TTC39B,HSPG2,SSH1,TSC22D3,PPFIBP2,PDGFRL,PLXNA1,CCNB1,PJA2,SLC20A1,CENPN,ELMOD2,CHST2,PAK6,CYP1A1,ANKS6,CTGF,ZNF823,IL31RA,SERINC2,AOX1,PIK3CA,KCNS3,ATRNL1,SNX16,IRF2,IQCD,HYLS1,SMYD5,ACVR1C,SNTB2,PBK,HSPA12A,MGAM,SLC35C1,KIF13A,TNS1,GALNT7,AURKB,CCNF,TP53I3,POR,ULK2,SFXN1,GNPTAB,LRIG1,BMP1,PRDM5,DHTKD1,MAPK13,TANC2,UNC5B,WBSCR27,RTN3,FGD1,DDX58,RECQL,MRC2,FRMD4A,TBC1D1,DGKQ,KIF23,SLC1A3,NOTCH2,APBA1,TNFRSF19,PDXDC1,KIAA1161,SH3RF2,MECOM,DOPEY2,ITGA3,LYPD3,BDH1,MSH2,DAPK1,SORL1,CD70,OSTF1,CACNA1D,PIKFYVE,ZNF117,EEF1D,GPR161,TMED2,TSPAN33,DNAI1,SOCS5,IGSF3,SPATA20,GCC2,KCNJ12,PRODH,TBC1D8B,DCHS1,PIP4K2C,WHSC1,ATP8B3,KDM3A,ANTXR1,NFIB,GLT8D2,FRMD4B,PDE11A,PRKAG2,PLEKHH2,TJP3,FAM64A,MATN2,SLC4A3,MPP2,ARAP1,FGD6,SFMBT1,CABIN1,SAMD8,PLIN3,MAP3K5,HOOK1,IFIH1,EHD1,PKD1L2,MFSD3,PLEKHG3,PLA2G4A,TCF25,SLC2A4,TCTN2,GPR107,CAPN12,REPS2,ARMCX3,TRIP10,CCDC110,IQGAP1,RALBP1,CERCAM,RPS6KA1,ATP2C2,IRX4,FTH1,RNF182,EGR3,CD274,FLT3,DDR1,GNB2,CYP39A1,ZFYVE9,EPS8L2,SLC25A35,C11orf84,APOBEC3B,CYHR1,APLP2,TRANK1,DOK4,CNNM4,TNPO2,PDE4D,LGMN,PHKA2,GPX4,TBC1D10B,MYO5B,DOCK4,CDKN2AIP,SLC5A11,SEC23A,COG2,TMEM43,FOXJ2,PANK1,CLSTN1,TEP1,UTRN,KIF1C,PRKCQ,PYGO1,C15orf39,CBL,ITPR3,H2AFV,ATP10D,FZD7,NIN,EPHA10,PPP2R5A,ACAD10,SLC27A1,NRG1,MLKL,ZC3H12B,SLC27A3,COBL,ATMIN,MAMDC2,MRPS9,PLSCR4,DEPDC1,SLC16A14,CDCA3,CCNJL,CBLL1,HERC5,NES,CYB561,PLD2,APOBEC3H,DNAH3,EFNB1,FGF19,TMCC3,RASSF8,E2F7,PHF7,PTEN,MGAT1,CENPJ,SGK3,CD9,CCDC82,TRIM62,NCOA2,OSGIN1,SMC4,FARP2,TGIF1,PDGFC,ALDH2,ARHGEF28,B3GNT2,ARAP2,LONRF3,TCFL5,MPP1,PARP4,ZKSCAN2,FURIN,C2orf69,FOS,CDK5RAP1,DCTN6,MAMDC4,PRDX3,RCBTB2,FGFR2,RIN3,ABCB1,CSTF2,ERAP1,CCDC69,GRIN2D,WDR62,SLC25A38,NCAPG2,ESPL1,MELK,JARID2,RGMA,EXPH5,EMX1,LTBP1,FAF2,CAMKK1,CPT2,UBE2Z,TAF6L,KREMEN1,TMC1,DENND2D,SH3KBP1,HTR1D,ARHGEF10L,ADPRHL1,NKAIN3,ZFYVE16,SIPA1L2,CDKL5,DPYSL2,PHTF1,ANKFN1,DLG1,CAPG,ANKRD12,TRPC1,SUN3,ARNT2,MYH14,TECR,SLC39A10,PTPRE,BTBD3,RASGRP1,CYP1B1,TDP1,ATL1,ASXL1,LAP3,RNF165,RGAG1,TCN2,MAN2A2,ZNF114,ARHGEF19,NEIL1,GPRC5B,FASTKD1,MADD,TDRD7,IARS2,TRIM45,CCDC74B,ZNF165,ADIPOR1,APBA2,CHPT1,PSMC1,PPP2R5D,MIIP,CPPED1,STARD3NL,PCSK5,ZNF395,PPP1R12A,SERPINE2,LRRFIP2,PEX6,BVES,ETV5,ABCG2,FAM81A,PHLPP1,ADAMTSL4,QSOX2,ZNF432,CA2,CES2,PFKL,KCNN4,COL6A1,PRKCI,SRP54,FNIP1,LIMCH1,KNTC1,C10orf54,HLA-C,NCEH1,SLC12A2,CCDC88A,SNED1,ELK3,PODXL2,GYLTL1B,PDE5A,KIAA1109,NUBP1,C3orf58,AMDHD1,STEAP1,MFSD7,RANBP9,EGFR,GLCE,GNAS,XKRX,TSC1,ONECUT1,INSR,SLC6A6,ALPK3,RHOBTB2,EGFL7,KIF12,AFAP1,RARG,CCNE2,NCKAP5,PAX6,ZSWIM5,FAM92A1,MORC4,COL18A1,IL27RA,MICALL2,EXT2,ARHGEF16,SAP130,LRRC45,SS18,ZNF687,KHNYN,SETDB2,FRYL,SMO,RPN2,STEAP3,EPB41L4B,ECE1,NFKB2,SCYL3,EBAG9,SEPHS1,PTPRU,ERBB2IP,CD40,TMTC2,DOCK5,ARHGAP35,BHLHB9,TLE1,SPTBN5,PLXND1,CYP2U1,REEP4,ABCA1,LIFR,KDELC2,GLIS3,FBLIM1,CDS2,ENO2,ARHGEF11,FRMD6,JKAMP,SHPRH,SERPINB9,LRP4,ARMC7,FAM134A,COL4A5,INTS8,NTAN1,ITGA2B,SYDE2,ZNF212,TMEM63A,HDAC9,KIF5B,TOP2A,CARD8,ADORA1,TAF1B,ADRBK1,LLGL2,BMP7,RRBP1,GALNS,BRD7,TRIM3,ARVCF,KANK2,IQGAP3,MYO5A,RBMS2,PGM1,PHF20L1,SUN2,DCAF6,ADAM17,RAB3B,NR4A1,PHLDB3,ASPM,RC3H2,SYBU,OGDHL,FAM73B,SPAG1,MAP1B,C2orf70,RND3,PRCP,DHRS2,CSGALNACT1,OTUB2,UACA,GLB1,ZMIZ1,SOX8,ATP6V1C1,L1CAM,RAB3IL1,SNPH,ZNF596 |
| 5.720e-03 | -5.16 | HAHTOLA_SEZARY_SYNDROM_UP | MSigDB lists | HAHTOLA_SEZARY_SYNDROM_UP | 92 | 23 | 17758 | 2588 |
RECQL,CD55,LGALS8,IQGAP1,PTTG1,NUSAP1,NTAN1,BARD1,KTN1,PRDX4,FAS,PAPSS1,STAT1,PRC1,CSGALNACT1,DYSF,PDXK,FAR2,ETHE1,IL10RB,SMC4,CKS2,GOLGB1 |
| 5.721e-03 | -5.16 | Ets | pfam domains | PF00178 | 28 | 10 | 16629 | 2504 |
ELK4,ELK3,ETS2,ETV5,ELF5,ELK1,ETV7,ETV4,ETS1,ELF3 |
| 5.724e-03 | -5.16 | Cell Cycle | REACTOME pathways | R-HSA-1640170 | 572 | 108 | 8202 | 1235 |
SUN1,CCNE2,CEP70,SPC25,FOXM1,TUBB4B,PSME2,PTTG1,NDC80,TP53,CUL1,NUF2,PSME1,KIF2C,LPIN3,CCNB1,PRKACA,BARD1,CENPN,CDKN2C,CCND1,WEE1,PCNA,PSMD1,NUP210,CCNA2,CNTRL,CEP78,PSMC2,PLK4,TUBG1,CDKN1B,CDKN2D,HSPA2,TUBA4A,PLK1,CENPA,SYNE2,CDC20,PRKAR2B,AURKB,RAD17,PKMYT1,CDC25C,CDK1,GINS4,OPTN,PRIM1,PPP2R5A,RBL1,PSMD3,PPP1CB,HDAC1,SGOL1,PSMC1,CNEP1R1,PPP2R2D,PPP2R5D,PPP1R12A,HJURP,CENPI,PSMD7,CDCA8,ERCC6L,PSMD10,KIF23,SPDL1,LMNA,CKAP5,TOP2A,RB1,CENPJ,TUBGCP6,NEK2,CKS1B,BUB1,KNTC1,NUP85,PSMA5,SMC4,REC8,SUN2,ZWINT,PSMB4,KIF20A,CENPC,B9D2,MYBL2,WHSC1,POLD3,BORA,SKA1,PSMA4,LEMD2,CDCA5,E2F1,AURKA,SSNA1,CENPE,NUP37,CEP41,NDE1,NCAPG2,CCNB2,UBE2C,ESPL1,NUP58,RAD21 |
| 5.727e-03 | -5.16 | glycogen catabolic process | biological process | GO:0005980 | 20 | 8 | 16441 | 2455 |
CALM2,GAA,PGM1,CALM1,PYGL,CALM3,PHKA2,PHKG2 |
| 5.727e-03 | -5.16 | wound healing, spreading of cells | biological process | GO:0044319 | 20 | 8 | 16441 | 2455 |
ARHGAP24,ADAM17,RHOA,PDCD10,CYR61,ACVRL1,DDR1,LCP1 |
| 5.727e-03 | -5.16 | epiboly involved in wound healing | biological process | GO:0090505 | 20 | 8 | 16441 | 2455 |
ARHGAP24,ADAM17,RHOA,PDCD10,CYR61,ACVRL1,DDR1,LCP1 |
| 5.727e-03 | -5.16 | stimulatory C-type lectin receptor signaling pathway | biological process | GO:0002223 | 121 | 29 | 16441 | 2455 |
PSMB4,TAB3,PSME2,CALM1,PSMD7,CALM3,PSMD10,CUL1,PSME1,ITPR2,ITPR3,PRKACA,PSMA4,BCL10,CALM2,PSMD1,FYN,PSMD3,PSMC2,NFKBIA,ITPR1,PAK2,PLCG2,UBE2D2,MAP3K7,NFKB2,SYK,PSMC1,PSMA5 |
| 5.731e-03 | -5.16 | cell cycle arrest | biological process | GO:0007050 | 153 | 35 | 16441 | 2455 |
PRKAA2,GAS2L1,NKX3-1,CDKN1C,PRKAA1,TP53,CUL1,TGFBR1,NOTCH2,VASH1,BARD1,TP73,CDKN2C,CALR,RB1,MSH2,CDKN1B,ZBTB49,CDKN2D,DUSP1,WNT10B,RGCC,STRADB,KIF20B,ILK,SESN1,RHEB,TSC1,PRKAG2,CGREF1,CAB39,PKD2,MAPK12,IRF1,RRAGD |
| 5.748e-03 | -5.16 | TTANTCA_UNKNOWN | MSigDB lists | TTANTCA_UNKNOWN | 892 | 157 | 17758 | 2588 |
LTBP1,ACVR1,TXN,ST13,PPM1J,SLC25A13,CAMKK1,FHDC1,CA8,ECI1,SPTB,DENND2D,PLS3,CDKN2C,PAK6,ALDH1A3,SLC44A1,MITF,CAPG,ATRNL1,TINAGL1,WBP4,SMARCA2,SNTB2,SERTAD4,ROR1,MAP2,LIMK1,HOXA9,MYLK,ARF6,RTN3,MAFF,PPP1R12A,LRRFIP2,RASA2,AIM1L,IGF1R,TIMP1,LRRN2,CYR61,LYPD3,FLRT3,ZIC5,FAM13B,MTMR10,PIM1,ZRANB1,DLX4,GAD1,PLCB2,TRAK2,DNAI1,ELK3,STRADB,TCF7,CYFIP2,NMT2,BCAR3,MAPKAPK2,AP1AR,TSC1,ETS2,MFSD2A,LTBP2,MAL2,MAP3K5,SEMA3A,RPS6KA3,ELK4,PAX6,GPR107,APOO,DGKA,SOD2,IRX4,IL13RA1,MICALL2,PRR7,SYTL2,CDK14,NOV,RNF220,KCTD15,ST5,WDR44,LMO4,FABP6,RTKN2,PDE4D,ACSL4,SCN2A,LMAN1,SULF2,C6orf1,SAT1,ERBB2IP,ATP10D,EBF2,NFIX,PTGS2,TAPBP,TTC12,PTK7,CORO1C,KLF5,EFNA5,PRIMA1,LIFR,NR3C2,IGFBP6,MPZL1,CPEB4,KLHL13,TAB3,SLC41A1,SDC4,HAL,FAM134A,COL4A5,ETS1,NFAT5,DNAJB9,NRP2,VPS26A,NEO1,PDIA4,FOXP2,CTNNBIP1,RRBP1,TAGLN2,HEXIM2,CITED2,RBMS2,DUSP1,HMMR,TGIF1,ARAP2,CASK,BCL9,TEF,PRICKLE1,RUNX3,SPAG1,PRDX4,PITX2,ARHGAP24,CCDC6,NEIL3,E2F1,FBXO44,SH3BGRL2,HMGA1,ZMIZ1,L1CAM,PKIA,DIS3L |
| 5.754e-03 | -5.16 | negative regulation of response to external stimulus | biological process | GO:0032102 | 264 | 55 | 16441 | 2455 |
SIGIRR,SEMA6B,PINK1,SERPINE2,NLRX1,UBASH3B,EPHA4,TP53,GATA3,NENF,PDGFB,ETS1,GSTP1,CORO1B,IER3,CD109,PDGFA,NOV,SPP1,ADORA1,PTEN,TSPAN6,PRKG1,DUSP10,KANK2,SEMA3G,IFIT1,WNT3A,MAPK7,SEMA3B,QSOX1,CASK,PSMB4,ITCH,MICB,PBK,PLAUR,SHARPIN,GRIN1,PTGER4,PPARA,CALCRL,F12,BBS2,ABR,SOCS3,SEMA4D,TRAF3IP1,NOD2,CHMP4B,GPER1,NDFIP1,SEMA3A,LZTS1,DRD1 |
| 5.754e-03 | -5.16 | CAGGTA_V$AREB6_01 | MSigDB lists | CAGGTA_V$AREB6_01 | 736 | 132 | 17758 | 2588 |
TMEM184B,TTC39B,HEBP1,XIAP,UBE2Z,TEX2,LYNX1,SEPT4,PDGFB,SH3KBP1,SLC9A7,CHPF,CDKN2C,PAK6,CDKL5,TSPAN6,SLC44A1,KCNS3,MANF,MYH14,STK35,C12orf65,KIF13A,ICMT,LDB2,PTGFRN,RNF19B,RAB2B,SLC44A3,DPYSL3,PLEKHG6,RBM47,KCNK1,DOLPP1,NRGN,E2F8,CAPN1,ZNF395,LRRFIP2,ETV5,STRN4,ASB9,FAM81A,DHRS3,S100A2,TNFRSF19,SH3D21,FRY,LYPD3,GATA2,PPP4R1,MTMR10,CACNA1D,TMEM8A,NCAM1,MDFI,CYP26B1,OXR1,NFIB,MUM1L1,PTPRF,ARAP1,AGBL5,MAP3K5,RPS6KA3,DOCK9,AVPI1,REPS2,GRHL2,CAST,CERCAM,IL13RA1,EGR3,PRKACA,C1orf116,IER3,PDGFA,SAP130,ST5,SH3BP1,XYLT2,REEP1,LHX6,BCL6,SMO,PDE4D,EGLN3,CLCN3,AGPS,CAPN6,KIF1C,ERBB2IP,ITPR3,CD40,NFIX,ALDH3B1,PAFAH1B3,PTK7,OVOL1,NRG1,KLF5,PRR15,NR3C2,MAMDC2,CMTM4,FLOT1,TEAD3,SIRPA,SIX4,FOXP2,SNX13,ITGB8,BMP7,GPC3,SGK3,TFAP2A,SPRY2,PVRL4,PDGFC,CASK,ARAP2,HMGN5,TACC1,FAM109A,NDRG3,PITX2,DBI,PGRMC1,FAM117A,FOXA1,PHC1,JARID2 |
| 5.765e-03 | -5.16 | regulation of cellular localization | biological process | GO:0060341 | 1211 | 212 | 16441 | 2455 |
DOC2A,LAMP1,EXPH5,ILDR1,TXN,LGR4,CACNA2D2,GATA3,LGI3,IL18,ITPR2,SYTL4,CCNB1,SDC1,BARD1,ERP29,SLC8B1,NCS1,CALM2,RAB15,CTNNB1,CABP1,SIVA1,DPYSL2,PASK,KCNS3,DLG1,ABCA2,TRPC1,MYRIP,RASGRP1,VPS11,TRIM8,ACVR1C,BNIP3L,NBPF3,EZR,PRKAR2B,SLC25A5,PNKD,CDK1,RAB2B,LCP1,ABR,TRIM9,PLCG1,KCNMB4,SLC25A4,DNM1L,RAB11FIP1,NOD2,ARF6,F2RL1,TC2N,DDX58,BMF,PPP1R12A,NFKBIE,BVES,HLA-E,UBASH3B,RAB23,CALM3,RACGAP1,FBLN1,IL18R1,ANO1,LMNA,RAC2,RB1,ITGA3,PFKL,RIMS3,KCNN4,NEK2,PRKCI,SORL1,MDFIC,CACNA1D,MAPK7,WNT3A,SYTL3,RIMS2,MDFI,GCC2,CALM1,PLS1,KIF20B,TP53INP2,EGFR,STX3,CDK5R1,GNAS,TMEM30A,CDCA5,NFKBIA,ITPR1,OSCP1,YOD1,TRPC3,TMEM173,DRD1,EHD1,LZTFL1,SORBS1,NF2,THRA,IQGAP1,TP53,ERBB2,P2RX7,CD274,BCL2L1,MICALL2,PRKACA,APC2,BCAP31,ARHGEF16,SYTL2,PER2,IER3,NOV,CDH1,SP100,RALB,DACT1,REEP1,SMO,TAX1BP3,CDH3,DAB2IP,TWIST1,PDE4D,RAB27B,F2R,MYT1,TMBIM1,CHP1,SIRT1,ERLEC1,BAG4,AKT1,PFKFB2,DMTN,PTGER4,VPS4B,PRKCQ,ITPR3,CD40,SNX12,FZD7,IRS2,PTGS2,FYN,PPP2R5A,WWTR1,INPP4B,EFNA5,NRG1,RAB29,SYT13,PRKAR1A,TCAF1,PINK1,NKX3-1,TRAF2,ARHGEF7,SDC4,PSMD10,TGFBR1,HMGN3,KCNC4,NEO1,KIF5B,CARD8,ADORA1,ADRBK1,OXCT1,LLGL2,PTEN,CDK16,BMP7,FAM20B,BAX,UBE2J1,TMBIM6,MAPK11,CPLX1,SYK,P2RX4,HES1,RAB3B,RHOA,PIK3R1,SYBU,LITAF,RGCC,VAMP3,PIM3,MAP1B,GPLD1,NUCB1,LDLRAP1,BANK1,SYT7,E2F1,ARRB1,PKD2,GPER1,SPCS3,FZD5,PKIA |
| 5.777e-03 | -5.15 | establishment or maintenance of cytoskeleton polarity | biological process | GO:0030952 | 6 | 4 | 16441 | 2455 |
KIF2C,NCKAP1,LMNA,CKAP5 |
| 5.777e-03 | -5.15 | positive regulation of cholesterol biosynthetic process | biological process | GO:0045542 | 6 | 4 | 16441 | 2455 |
POR,PRKAA1,ABCG1,SEC14L2 |
| 5.777e-03 | -5.15 | actin filament reorganization | biological process | GO:0090527 | 6 | 4 | 16441 | 2455 |
FRY,DMTN,FRYL,ARAP1 |
| 5.777e-03 | -5.15 | regulation of microvillus assembly | biological process | GO:0032534 | 6 | 4 | 16441 | 2455 |
ATP8B1,KLF5,PLD1,RAP1GAP |
| 5.777e-03 | -5.15 | fungiform papilla development | biological process | GO:0061196 | 6 | 4 | 16441 | 2455 |
HDAC1,WNT10B,CTNNB1,SIX4 |
| 5.777e-03 | -5.15 | renal interstitial fibroblast development | biological process | GO:0072141 | 6 | 4 | 16441 | 2455 |
ACTA2,HES1,OSR1,PDGFB |
| 5.777e-03 | -5.15 | negative regulation of metalloenzyme activity | biological process | GO:0048553 | 6 | 4 | 16441 | 2455 |
TIMP2,TIMP3,TIMP1,TMBIM1 |
| 5.782e-03 | -5.15 | metal ion binding | molecular function | GO:0046872 | 4013 | 647 | 16491 | 2452 |
DOC2A,ACACB,TRIM24,TRIM5,SLC25A13,RET,CACNA2D2,XIAP,LACTB2,SYTL4,CA8,BARD1,LTBP3,PHF1,ZNF275,EPDR1,TP73,CALM2,WEE1,ZYX,CABP1,CYP2S1,KLF3,ATP13A3,PPP1CA,WBP4,RNF26,TIPARP,CPE,APOBEC3G,ERAP2,NEK4,VPS11,RNF11,SPRTN,CDA,LOXL2,RNF19B,PNKD,CYP4F3,LCP1,PIAS3,ENPP1,PLCG1,TRIM47,LIMK1,ATP7B,MYLK,AGFG2,RNASEL,ANXA11,NUAK1,CYP2J2,ITGA6,MTL5,ZNRF3,HPCAL4,RABGGTA,MARCH8,GNS,DNPEP,ZCCHC17,WDFY1,MEGF8,PRICKLE4,ZIC5,NEK2,CADPS2,ZMYM1,MOXD1,DGKG,MYLIP,SALL4,SHARPIN,FHL2,PLS1,GNA11,DCP2,CYB5A,TIMM8A,S100A5,DYSF,B4GAT1,DRP2,ZNF502,RPS6KA3,CSRP2,XDH,ADAMTS16,EGLN1,DMPK,RNF224,LFNG,GALNT12,RHBDL3,TESK2,MOCS1,REPS1,ZNF385B,RCN1,RNF220,CDH1,ENPP5,MYT1,RNF169,ENPP4,ERMP1,APOBEC3D,XRCC6BP1,TRIM7,ZNF618,EBF2,PDLIM3,TRABD2A,PDXK,GEN1,MAPK12,HSP90B1,MAN1A2,TRAF2,ZNF219,NUCB2,DTX3L,CAPN2,ZFX,ARSG,MGAT4A,FAM20B,ZFAND4,PLEKHF1,ADAM15,ZNF230,NPTXR,RAG1,S100A6,MOB4,ADAMTS2,NUDT8,PLSCR1,RAPGEF2,GRIN1,DBR1,BLVRA,NEURL1B,ABLIM2,GALNT3,PLOD2,ATXN7L3,ACVRL1,NR1D2,SYT7,ZFP30,NR4A3,ARFGAP3,ITGAV,FHL1,OSR1,CYBRD1,PHC1,TLL2,MYL9,UNKL,TRIM2,AGRN,CNOT8,MCCC1,LMCD1,PHOSPHO1,NENF,MGAT5B,CDIPT,HDAC6,PLS3,RPS6KA2,NPNT,ARL1,LMAN2L,MKRN3,DDHD2,PAPL,DDX59,S100A13,ZNF462,THRB,PCGF5,KCNIP3,MARK1,ING1,MCTP1,CELSR2,ESYT1,IDH1,ZBTB7B,RHEB,KDM4D,DZIP1L,TRIM9,PLCH1,KLF12,P4HA2,ZNF367,KLF11,POMT1,TC2N,MYL12B,PRKAA2,PARP12,LMTK3,ZCCHC24,RASA2,RACGAP1,B4GALT4,FBLN1,RSAD1,TIMP1,GATA2,FRAS1,PIM1,PLCB2,CYP26B1,CHSY3,PCDH1,TESK1,ZNF320,MGAT4B,ZSCAN12,ZDHHC3,G2E3,CDK5R1,RASGRP2,ZC2HC1A,FA2H,PHLPP2,ITGA7,PRPS2,P4HA3,ZDHHC7,LTBP2,ZDBF2,RNF146,UGP2,P3H2,CTDSPL,DGKA,TP53,ZNF28,RASGRP3,CYP26A1,SYTL2,SDF4,LMO4,LHX6,SRR,BCL6,ZDHHC23,CDH3,VAT1,NOTCH3,OAS3,LMAN1,EGLN3,CTDSP2,SULF2,CPD,SIRT1,TIMP2,FIGNL1,S100A4,ACO1,MYL12A,DAG1,ATP13A2,ZNF628,DUOX1,PTGS2,IDE,ATP1A1,MMP17,STK38,ADAMTS14,ANXA9,ZBTB6,SYT13,AIFM3,LTA4H,ZNF701,ZC3HC1,CTDSP1,MAN2B2,ZMAT1,PINK1,DYRK3,CDH22,TAB3,SCD5,GNE,GNAL,MCTP2,ERI2,GTF3A,JAG2,NRP2,PPP2R3A,ZDHHC21,FOXP2,ALPP,TRIM21,HMGCL,KLF9,ATP2B1,FAH,P2RX4,FBLN5,NR3C1,AMFR,CRIP2,PPARA,PRICKLE1,TRIM35,CAPNS1,RNPEP,DGKE,DDAH1,FAT4,NEIL3,ZMYND19,ZNF214,PPP2R3C,PKD2,ZBTB33,ACVR1,HSPG2,ATP8A1,GATA3,PJA2,NCS1,PICK1,ASPHD2,HELZ2,CYP1A1,ZNF823,STIM1,PRICKLE3,ZFP36,POLL,STEAP2,AOX1,MARCH2,ZBTB18,SMYD5,METAP2,ACVR1C,PIF1,GALNT7,AURKB,MCFD2,ZFAND5,TP53I3,POR,PRIM1,GDE1,GNPTAB,PTER,NKD1,PRDM5,BMP1,TRAF5,FGD1,DDX58,KLF2,DGKQ,CALB2,ADO,PRKAA1,NOTCH2,S100A2,PRRG4,MECOM,SH3RF2,CALR,ITGA3,ZNRF2,NECAB3,MSH2,CACNA1D,PIKFYVE,MAST4,SYTL3,ZNF117,RIMS2,PMPCB,ZNF84,MFI2,TBC1D8B,CALM1,DCHS1,WHSC1,ATP8B3,PKM,KDM3A,JADE2,ANTXR1,PDE11A,DGKH,MMP15,NT5C2,ZDHHC20,MATN2,ARAP1,PIAS2,AGBL5,FGD6,PCDH19,NR4A2,ZBTB34,MAP3K5,IFIH1,EHD1,PKD1L2,PLA2G4A,REPS2,CAPN12,S100A11,THRA,RPS6KA1,IQGAP1,SUZ12,ATP2C2,FTH1,RNF182,EGR3,NUDT12,DDR1,CYP39A1,ZFYVE9,APOBEC3B,APLP2,CYHR1,ZNF75D,ACAP2,RNASEH2A,PDE4D,NR2C1,SEC23A,CLSTN1,UTRN,COX11,PRKCQ,SLC11A2,PKMYT1,PYGO1,ATP1B1,CBL,ATP10D,SP4,ZNF469,NIN,ZMPSTE24,AMZ2,FYN,ZNF641,STK26,NGFRAP1,HAGHL,ZNF704,PPP1CB,EFCAB14,KLF5,ZC3H12B,B4GALT3,NR3C2,ATMIN,PLSCR4,ATP9A,EFHD2,CBLL1,APOBEC3H,CYB561,RNF128,PHF7,MGAT1,PTEN,PPP1R10,ATP8B1,ERCC2,MAP3K7,CNOT6L,GFI1,TRIM62,MSH6,ARHGEF28,ARAP2,LONRF3,PAPD7,ZC3H11A,FURIN,ZKSCAN2,AIF1L,ARSK,CDK5RAP1,NUCB1,TIMP3,PGM2L1,ERAP1,LRRK1,ARSB,MELK,ESYT2,USP16,NMRK1,LTBP1,DNER,TRIM68,CHPF,ADPRHL1,ZFYVE16,ZCCHC12,IMPAD1,SIVA1,ASH2L,NFU1,MYRIP,RASGRP1,SP5,CYP1B1,SOD1,TRIM8,CXXC5,ASXL1,LAP3,RNF165,TCN2,CXXC4,MAN2A2,NEIL1,ZNF114,TRIM45,ZNF165,SP6,ADIPOR1,CHPT1,CPPED1,CAPN1,NR2C2,LASP1,ARAP3,ZNF395,CALM3,TEC,PHLPP1,ZNF432,CA2,PFKL,FAM20C,EBF4,PRKCI,LIMCH1,ZNF692,ZRANB1,SNED1,GYLTL1B,PDE5A,RNF113A,NUBP1,STEAP1,AMDHD1,FECH,GNAS,NUDT16,CGREF1,PAPD5,YOD1,EGFL7,RARG,KLF7,LMO7,SLC25A24,ZSWIM5,SOD2,GMPR,COL18A1,MORC4,ZMYND10,OSR2,MICALL2,EXT2,ZNF687,SETDB2,CYP4F11,ZDHHC12,ZBTB49,STEAP3,ECE1,APIP,ETHE1,LOXL1,CHP1,MAP3K3,ZNF525,GCA,RFK,GLO1,MAP3K6,JADE1,PEX2,OVOL1,CANT1,CYP2U1,GLIS3,FBLIM1,ANXA3,ENO2,SHPRH,CIT,LRP4,TGFBR1,ITGA2B,HDAC9,ZNF212,IRF2BPL,TOP2A,MLPH,TAF1B,GALNS,ZDHHC13,TRIM3,MYO5A,PHF20L1,PGM1,ADAM17,NR4A1,GCLC,RC3H2,OGDHL,MBNL3,ENDOD1,MARC1,SWAP70,TRIM69,FIBCD1,DTX4,TADA2B,CSGALNACT1,GEM,PLOD3,ZMIZ1,ZNF596 |
| 5.784e-03 | -5.15 | hair cycle | biological process | GO:0042633 | 90 | 23 | 16441 | 2455 |
LGR4,SOX9,LRP4,TFAP2C,LDB2,SAV1,TNFRSF19,FZD6,EGFR,ZDHHC21,CD109,PDGFA,GNAS,PTGS2,CTNNB1,FGFR2,CTSV,DBI,SMO,HDAC1,CDH3,ERCC2,HOXC13 |
| 5.784e-03 | -5.15 | molting cycle | biological process | GO:0042303 | 90 | 23 | 16441 | 2455 |
LGR4,SOX9,LRP4,TFAP2C,LDB2,SAV1,TNFRSF19,FZD6,EGFR,ZDHHC21,CD109,PDGFA,GNAS,PTGS2,CTNNB1,FGFR2,CTSV,DBI,SMO,HDAC1,CDH3,ERCC2,HOXC13 |
| 5.805e-03 | -5.15 | Regulation of CDC42 activity | Pathway Interaction DB | cdc42_reg_pathway | 30 | 13 | 2227 | 480 |
BCAR3,PLCG1,MCF2L,ARHGEF7,RALBP1,SPATA13,RACGAP1,DOCK11,ARHGEF9,NGEF,FARP2,FGD1,DOCK9 |
| 5.825e-03 | -5.15 | UBD (ubiquitin D) | protein interactions | 10537 | 19 | 8 | 16036 | 2547 |
PSMB4,LRRFIP2,NUB1,TP53,UBE2Z,TGFBR1,HDAC6,USP16 |
| 5.828e-03 | -5.15 | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP | 179 | 39 | 17758 | 2588 |
CD99,EPS8,SELL,MGST2,DOCK11,IGF1R,RALGPS2,ZNF823,LRRC6,SLC44A1,MITF,STT3B,TRAM1,CCDC88A,CERS2,SOAT1,ERMP1,ANO6,COX11,CBL,KDM3A,NDRG3,IL1R1,INSR,SWAP70,NR1D2,WIPI1,CORO1C,STK38,PLA2G15,PPP2R4,RAB11FIP1,CAB39,MLKL,WDR91,RTN3,CBX4,EGLN1,CTDSP1 |
| 5.828e-03 | -5.15 | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN | 179 | 39 | 17758 | 2588 |
PLA2G4A,TXN,UGP2,IL15RA,IL15,HAPLN3,SEC61G,PSME2,PPFIBP2,SOD2,SAMD9,CD274,MORF4L2,HERC6,PDGFA,ITGB8,CD70,SELK,LRIF1,TMED2,LAMP3,PARP9,IFITM3,STAT4,NUB1,CDYL,EMP3,AK4,BLVRA,DUSP4,FNDC3A,STEAP1,PI4K2B,BTG1,CASP7,SWAP70,SERPINA1,ALG2,ZNF701 |
| 5.835e-03 | -5.14 | regulation of mesenchymal cell proliferation | biological process | GO:0010464 | 37 | 12 | 16441 | 2455 |
CTNNBIP1,IRS2,PDGFA,CTNNB1,FGFR2,TBX1,SOX9,TBX18,SMO,STAT1,SHOX2,NFIB |
| 5.854e-03 | -5.14 | LIN7A (lin-7 homolog A (C. elegans)) | protein interactions | 8825 | 35 | 12 | 16036 | 2547 |
KCNJ12,ZYX,CASK,SNTB2,DLG1,MPP2,MPP5,DLG3,APBA1,PXDC1,SLC20A1,ABCA1 |
| 5.860e-03 | -5.14 | CH | smart domains | SM00033 | 66 | 19 | 9131 | 1455 |
LMO7,GAS2L1,ASPM,ARHGEF7,IQGAP1,SYNE2,UTRN,PLS1,MICALL2,SPTB,LCP1,PLS3,SMTNL2,CLMN,LIMCH1,DIXDC1,SPTBN5,TAGLN2,IQGAP3 |
| 5.861e-03 | -5.14 | neural crest cell differentiation | biological process | GO:0014033 | 75 | 20 | 16441 | 2455 |
SEMA6B,HES1,ACVR1,RET,SOX9,FGF19,EFNB1,GBX2,EDNRA,PITX2,SEMA4D,CORO1C,TBX1,SMO,TWIST1,NRG1,SEMA3G,SOX8,SEMA3A,SEMA3B |
| 5.870e-03 | -5.14 | regulation of JUN kinase activity | biological process | GO:0043506 | 80 | 21 | 16441 | 2455 |
FZD4,TRAF2,EPHA4,PKN1,GSTP1,MAP3K6,TP73,KIAA1804,MAP3K11,MAP3K9,DUSP10,DAB2IP,MDFIC,MAP3K5,FZD5,MAP3K7,SYK,GAB1,HIPK3,DVL2,MDFI |
| 5.893e-03 | -5.13 | ROCK1 (Rho-associated, coiled-coil containing protein kinase 1) | protein interactions | 6093 | 48 | 15 | 16036 | 2547 |
ARHGAP24,CASP3,MBP,CASP7,RHOA,ADD1,PPP1R12A,PTEN,RND3,DPYSL2,LIMK1,CFAP206,EZR,ARRB1,GAB1 |
| 5.896e-03 | -5.13 | REACTOME_SIGNALING_BY_FGFR | MSigDB lists | REACTOME_SIGNALING_BY_FGFR | 108 | 26 | 17758 | 2588 |
AKT1,NR4A1,CASP9,CALM1,PIK3R1,CALM3,PRKAR2B,ITPR2,PHLPP1,ITPR3,CBL,PRKACA,CDK1,FGF19,CALM2,PLCG1,ADRBK1,PTEN,FGFR2,FGF18,PIK3CA,CDKN1B,SPRY2,GAB1,FRS3,PRKAR1A |
| 5.896e-03 | -5.13 | GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_DN | MSigDB lists | GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_DN | 196 | 42 | 17758 | 2588 |
ELK4,CPT2,FAM129B,ARHGEF7,HAL,TAP1,ATP6V1E2,ITGA2B,XPR1,IER3,BMP2,AP1M2,CDK16,TRIM3,ECE1,ERBB3,PXMP4,CAMK2G,CYP1B1,ARAP2,B9D2,FOXJ2,CDC20,MGAT4B,CRIP2,FURIN,FAM73B,ELK1,MYOM1,KDM3A,TJP3,SH2D3C,SLC35B3,ZNF704,ARRB1,EGFL7,ACADM,LTBP2,NDE1,NRGN,UBE2C,USF2 |
| 5.906e-03 | -5.13 | human chr9q34.3 | chromosome location | human chr9q34.3 | 103 | 20 | 26250 | 2805 |
RNF224,TPRN,TOR4A,GRIN1,UBAC1,NPDC1,QSOX2,C9orf69,INPP5E,MAMDC4,AGPAT2,NOXA1,ZMYND19,ARRDC1,RABL6,SSNA1,EGFL7,CYSRT1,PTGES,FBXW5 |
| 5.920e-03 | -5.13 | DERL1 (derlin 1) | protein interactions | 79139 | 57 | 17 | 16036 | 2547 |
FAF2,TCF25,MFI2,AMFR,ESYT1,POR,BCAP31,HLA-A,EGFR,VCP,PTGS2,SERPINA1,UBE2J1,YOD1,TRAM1,ESYT2,EPHX1 |
| 5.942e-03 | -5.13 | KRIEG_HYPOXIA_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_VIA_KDM3A | 52 | 15 | 17758 | 2588 |
NFKBIE,FAM64A,PLAUR,FABP6,STEAP3,VEZT,GDF15,COL7A1,KIF2C,KDM3A,SYTL3,IL1RAP,NRP2,SEC14L2,RRAGD |
| 5.942e-03 | -5.13 | LIANG_SILENCED_BY_METHYLATION_2 | MSigDB lists | LIANG_SILENCED_BY_METHYLATION_2 | 52 | 15 | 17758 | 2588 |
MX1,PTGS2,SP100,AREG,DHRS2,S100A4,BIK,STAT1,SOD2,IRF7,IFIT1,IFIT3,IFI6,STX3,ICAM1 |
| 5.942e-03 | -5.13 | SMIRNOV_RESPONSE_TO_IR_2HR_DN | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_2HR_DN | 52 | 15 | 17758 | 2588 |
PLA2G4A,KLF2,PSRC1,CENPA,KIF20A,DEPDC1,JRKL,RGS3,STK38,AURKA,TTC9,KDM3A,SLC35A1,ATP10D,FAM69A |
| 5.948e-03 | -5.12 | MAP kinase activation in TLR cascade | REACTOME pathways | R-HSA-450294 | 60 | 17 | 8202 | 1235 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,NOD2,MAPK11,MAPK7,MAP3K7,PPP2R5D,RPS6KA3 |
| 5.949e-03 | -5.12 | CREB phosphorylation through the activation of CaMKK | REACTOME pathways | R-HSA-442717 | 6 | 4 | 8202 | 1235 |
CALM3,CALM2,CAMKK1,CALM1 |
| 5.949e-03 | -5.12 | Phosphorylation of Emi1 | REACTOME pathways | R-HSA-176417 | 6 | 4 | 8202 | 1235 |
PLK1,CCNB1,CDK1,CDC20 |
| 5.952e-03 | -5.12 | Nuclear Events (kinase and transcription factor activation) | REACTOME pathways | R-HSA-198725 | 24 | 9 | 8202 | 1235 |
MAPKAPK2,RPS6KA2,RPS6KA1,MAPK11,DUSP4,MAPK7,ELK1,PPP2R5D,RPS6KA3 |
| 5.958e-03 | -5.12 | N-Glycan biosynthesis | KEGG pathways | ko00510 | 49 | 15 | 6908 | 1076 |
MAN2A2,DDOST,MGAT1,MGAT4A,ALG13,MAN1A2,DOLPP1,FUT8,MGAT4B,RPN2,MGAT5B,STT3B,ALG2,B4GALT3,MGAT5 |
| 5.958e-03 | -5.12 | N-Glycan biosynthesis | KEGG pathways | hsa00510 | 49 | 15 | 6908 | 1076 |
MAN2A2,DDOST,MGAT1,DOLPP1,MGAT4A,ALG13,MAN1A2,MGAT4B,FUT8,RPN2,MGAT5B,STT3B,ALG2,B4GALT3,MGAT5 |
| 5.961e-03 | -5.12 | FBA | pfam domains | PF04300 | 6 | 4 | 16629 | 2504 |
FBXO44,FBXO6,FBXO27,FBXO2 |
| 5.961e-03 | -5.12 | PET | pfam domains | PF06297 | 6 | 4 | 16629 | 2504 |
PRICKLE1,PRICKLE4,PRICKLE3,LMCD1 |
| 5.961e-03 | -5.12 | Kinesin_assoc | pfam domains | PF16183 | 6 | 4 | 16629 | 2504 |
KIF1C,KIF13A,KIF14,KIF13B |
| 5.966e-03 | -5.12 | CREBBP (CREB binding protein) | protein interactions | 1387 | 352 | 74 | 16036 | 2547 |
CCNC,ACVR1,HOXB7,EPAS1,FOXM1,TRIP10,THRA,RPS6KA1,PTTG1,TP53,TAF6L,RAD23A,TP73,CCND1,PCNA,CCNA2,RPS6KA2,CTNNB1,CDH1,ZCCHC12,TACC2,FOSB,BCL6,MYBL1,SMARCA2,ING1,AKT1,CDC20,SERTAD3,BNIP3L,PIAS3,HLF,STAT6,HOXA9,STAT1,HDAC1,KLF5,KPNA2,IRF7,ABCA1,KLF2,RUNX2,SOX9,ETS1,HOXB2,ICAM1,MECOM,ELF3,CENPJ,MSH2,ACTA2,CITED2,NCOA2,MSH6,NR3C1,STAT4,MYBL2,FHL2,MAML2,ELK1,TXNDC11,FOS,NCOA3,ONECUT1,SERTAD2,ETS2,HTT,E2F1,FHL1,HMGA1,MAP3K5,CTBP1,RPS6KA3,IRF1 |
| 5.977e-03 | -5.12 | mucinous | COSMIC cancer mutations | mucinous | 38 | 12 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 5.977e-03 | -5.12 | soft_tissue-nerve_sheath-malignant_peripheral_nerve_sheath_tumour | COSMIC cancer mutations | soft_tissue-nerve_sheath-malignant_peripheral_nerve_sheath_tumour | 38 | 12 | 17775 | 2585 |
RB1,SS18,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR |
| 5.978e-03 | -5.12 | STAT3 (signal transducer and activator of transcription 3 (acute-phase response factor)) | protein interactions | 6774 | 212 | 48 | 16036 | 2547 |
RUNX2,FOXM1,TRIP10,RET,MORC4,PDIA3,ERBB2,GNB2,HLA-A,IL22RA1,CCND1,RB1,IGF1R,IRAK1,GATA2,IL6ST,TBCD,MSH2,RP2,MAP3K7,NFKB2,SYK,IL1RAP,SIRT1,HES1,ASXL1,NR3C1,NR4A1,STAT4,FHL2,OGDHL,CAPNS1,ERBB2IP,FOS,LEPR,EGFR,PIAS3,FYN,IDE,JAK1,FGFR2,STAT6,NMI,STAT1,HDAC1,NFKBIZ,JAK3,CAPN1 |
| 5.984e-03 | -5.12 | astrocytoma_Grade_II | COSMIC cancer mutations | astrocytoma_Grade_II | 633 | 115 | 17775 | 2585 |
ARHGAP11A,MTM1,ACVR1,NF2,GPR107,HSPG2,PPM1J,CERCAM,RET,TP53,ERBB2,PDGFRL,TDRKH,PLXNA1,EXT2,ART5,PICK1,PAK6,TYMP,MUC16,ZNF687,ARTN,CTNNB1,STIM1,CYP4F11,IQCE,PIK3CA,ZDHHC23,RTKN2,GLB1L2,NOTCH3,NR2C1,RASGRP1,SCN3A,TRIM8,AKT1,SYNE3,ASXL1,CAPN6,UTRN,PRKRA,IDH1,MYOM1,POR,PTGS2,HS6ST1,JAK1,ATP7B,SH2D3C,SPTBN5,RGS14,NXT2,FARP1,MRC2,USH1C,CDK17,FRMD4A,SCD5,PYROXD2,CDCA3,ASAH1,NES,SORBS3,JAG2,DNAH3,FAM167A,M6PR,RB1,RAC2,DOPEY2,ANK1,DNPEP,IGSF9,RNF128,ADRBK1,ALPP,PTEN,FAM160A2,MEGF8,TUBGCP6,FDXR,TPST1,BRD7,ARVCF,KANK2,MAPK11,PIM1,IQGAP3,CCDC88A,RIMS2,PARP9,ACBD5,SPATA20,PCDH1,KLK5,ERMAP,MFSD2B,RC3H2,PIK3R1,KIAA1109,AKAP3,NPHP3,FNDC3A,GNA11,EGFR,USP6,GNAS,LDLRAP1,TJP3,PLA2G15,NLRC5,CSTF2,CPEB2,TMEM131,ESYT2 |
| 5.993e-03 | -5.12 | CATATPASE | prints domains | PR00119 | 35 | 11 | 4759 | 661 |
ATP1A1,ATP9A,ATP7B,ATP8A1,ATP13A3,ATP2C2,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 5.997e-03 | -5.12 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | MSigDB lists | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | 29 | 10 | 17758 | 2588 |
MAP3K3,CASP3,BAG4,NFKBIE,RALBP1,TRAF2,NFKBIA,NFKB2,MAP3K7,NR2C2 |
| 5.997e-03 | -5.12 | CHOW_RASSF1_TARGETS_DN | MSigDB lists | CHOW_RASSF1_TARGETS_DN | 29 | 10 | 17758 | 2588 |
DDB2,CELSR2,P4HB,ARL1,RUNX3,HSPA13,PPP1CA,EEF1D,EBAG9,OPTN |
| 5.997e-03 | -5.12 | RAS_GTPASE_ACTIVATOR_ACTIVITY | MSigDB lists | RAS_GTPASE_ACTIVATOR_ACTIVITY | 29 | 10 | 17758 | 2588 |
ARHGEF10L,DOCK4,ARAP3,RAPGEF2,RALBP1,RASA2,ARAP1,RASGRP3,ARHGAP4,RASA1 |
| 5.997e-03 | -5.12 | LY_AGING_PREMATURE_DN | MSigDB lists | LY_AGING_PREMATURE_DN | 29 | 10 | 17758 | 2588 |
PTGS2,CENPA,FOXM1,RANBP1,MYBL2,CKS1B,KIF2C,PKMYT1,CCNF,BARD1 |
| 5.997e-03 | -5.12 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | MSigDB lists | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | 29 | 10 | 17758 | 2588 |
CASP3,BMF,CASP7,AKT1,CASP9,XIAP,E2F1,TP53,BAX,BCL2L1 |
| 5.997e-03 | -5.12 | REGULATION_OF_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | REGULATION_OF_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | 29 | 10 | 17758 | 2588 |
ARHGEF10L,TSC1,MID1IP1,NF2,CAPG,ARAP1,SORBS3,ARF6,CCDC88A,RASA1 |
| 5.997e-03 | -5.12 | PID_REELIN_PATHWAY | MSigDB lists | PID_REELIN_PATHWAY | 29 | 10 | 17758 | 2588 |
FYN,ITGA3,AKT1,PIK3R1,MAP3K11,PIK3CA,CBL,CDK5R1,MAPK8IP1,MAP1B |
| 6.014e-03 | -5.11 | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | MSigDB lists | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | 265 | 54 | 17758 | 2588 |
TRIM24,EPS8,C5orf30,BCL2L1,RAB6A,PJA2,PDGFB,LBR,SIRPA,TOP2A,CYHR1,WEE1,PCNA,RNF220,CCNA2,CTGF,UBE2T,FRYL,PSMC2,BUB1,MAP3K7,SPRY2,PSMA5,SIRT1,PLK1,GCC2,TGIF1,CXXC5,MRPS35,FNDC3A,ANLN,POLD3,LHFPL2,KIF11,CDC25C,STK17B,CDK1,PSMA4,EGFR,CDK5R1,STK17A,LRRC42,BTG1,FYN,FNTA,MID1IP1,DCK,CORO1C,NMI,UBE2D2,AURKA,HS3ST3B1,UBE2C,SRSF9 |
| 6.016e-03 | -5.11 | MODULE_94 | MSigDB lists | MODULE_94 | 359 | 70 | 17758 | 2588 |
EXPH5,ACACB,IL15RA,HOXB7,GRIK2,IL27RA,EGR3,CHPF,IER3,NOV,TGFBR3,CABP1,CDKN1B,ARNT2,MTMR11,ACSL4,PTPRE,RASGRP1,KIAA0040,TEP1,KDELR3,CR2,SLC11A2,PRKCQ,ROR1,F12,DUSP4,MYOM1,PEX5,GPRC5B,ATP7B,SERPINI1,ITPKA,F2RL1,GCLM,NKX3-1,PACSIN2,CDH22,ARHGEF11,CYP2J2,BIK,EPS8,ARL4C,GABRG2,CNTNAP2,APBA1,SEPP1,PPP2R3A,RND1,CARD8,PFKL,RIMS3,TPST1,DAPK1,TTLL1,FARP2,HES1,PCDH1,PLEKHA6,GRIN1,COL7A1,PLS1,STEAP1,MFSD7,IL1R1,SCG2,CSTF2,NR4A2,HOXB13,TMEM159 |
| 6.017e-03 | -5.11 | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 7783 | 1191 | 17775 | 2585 |
HECA,FAM160B1,IBTK,GRIK2,PNPLA2,HEXB,RET,DPP8,FAM46C,SPSB1,CARD10,ZNF275,CDKN2C,NAPG,PHYHIP,PPP1CA,RNF26,WBP4,TIAM1,IL10RB,MGAT5,CCDC74A,PNKD,ABR,PLCG1,ATP7B,TRAF3IP1,FAM114A1,NOD2,RNASEL,STARD13,ANXA11,SCN5A,ITGA6,RAB23,ARHGEF35,FAM21C,HPCAL4,RABGGTA,TFAP4,FLII,FRY,PAIP2B,RIMS3,MEGF8,FBXL14,MAP3K9,SLAIN2,PANX2,MAPK7,ZMYM1,MOXD1,DGKG,NUP85,MCCC2,HPS3,FHL2,NPHP3,DPYSL4,PLIN5,CACHD1,FNTA,SLC4A4,S100A5,DGAT2,CLMN,TMEM173,RUSC1,ADAMTS16,DMPK,DOCK9,WDR63,NQO1,GRK6,FAM91A1,REPS1,RBM23,MUC16,ST5,CDH1,RASGEF1A,LRP11,MYT1,SNX8,COL6A2,ERMP1,APOBEC3D,PTPN9,HTATIP2,XRCC6BP1,TANC1,ZNF618,EBF2,GIGYF1,CCNB3,SHROOM3,CDK19,WFS1,AXL,MAPK12,CTHRC1,HSP90B1,FAM189A2,CKAP2,ESRP1,BACE1,TRAF2,CCM2,OSGIN2,BTN3A1,CTSZ,PLPPR4,NFAT5,BEX2,SLC25A45,PDCD10,FUT2,ITGB8,IGSF9,GPC3,MGAT4A,TMEM62,CST3,TUBGCP6,FAM20B,KLC3,FAM102A,RAG1,MED22,PARP9,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,CXorf57,C4orf27,CNTNAP1,RAB11FIP2,SLC35B3,CD81,PHC1,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,ARFGEF1,TEX2,NENF,MGAT5B,ITPR2,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,ENTPD4,NUP210,CTNNB1,RABEP2,P4HB,IL6ST,PAPSS1,TMEM143,ABCA2,PLK1,PTPN18,MARK1,CELSR2,STAU2,NFE2L1,CCBL2,ARFRP1,EAF2,DZIP1L,KDM4D,TNS4,HS6ST1,TRAM2,KLF12,ARRDC1,KLF11,RUNX2,USH1C,HJURP,DNAJB2,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,FRAS1,KIF13B,AHCY,FAR2,WNT3A,MPHOSPH9,CKAP4,USP31,BTNL9,RGMB,SCRIB,PRX,NMT2,C18orf8,COL13A1,PHLPP2,NLRC5,ZDBF2,CDAN1,CCNB2,RAD21,TMX4,TP53,RHPN2,SYTL2,IER3,PDGFA,TTC21B,WDR44,TACC2,BCL6,ZDHHC23,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,CTDSP2,SULF2,CLCN3,AKT1,ACO1,C3orf33,DAG1,ATP13A2,ZNF628,IDE,PTPRJ,PAFAH1B3,RBL1,XRCC3,ARHGAP4,ZMAT1,BIN1,PINK1,DYRK3,CDH22,CPEB4,TAB3,KLHL13,SCD5,MCTP2,ERI2,ERCC6L,GTF3A,PARM1,VPS26A,IL22RA1,NRP2,M6PR,CD109,FOXP2,ALPP,CDK16,IL17RA,TRIM21,ALDH7A1,HMGCL,FAM134C,ATP2B1,LRRC24,NFE2L3,FBLN5,GUSB,DPP9,MAML2,COL7A1,RNPEP,TXNDC11,USP6,BCL10,DDAH1,PTGES,HIPK3,GOLGB1,FAM171B,LAMP1,SLC35D2,LGR4,HSPG2,SSH1,TSC22D3,PDGFRL,PJA2,PICK1,PAK6,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,POLL,PIK3CA,KCNS3,SNX16,IRF2,TACSTD2,HYLS1,MARCH2,ACVR1C,SLC35C1,KIF13A,POR,SH2D3C,LRIG1,PRDM5,BMP1,MAPK13,WBSCR27,FGD1,SEMA6B,RECQL,MRC2,TBC1D1,APBA1,TNFRSF19,PDXDC1,SH3RF2,MESDC2,DOPEY2,RALGPS2,LYPD3,MSH2,DAPK1,PRKG1,OSTF1,CACNA1D,DLX4,KCTD3,ZNF117,GPR161,SOCS5,SPATA20,GCC2,PRODH,KCNJ12,DCHS1,WHSC1,ATP8B3,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,PLEKHH2,TJP3,FAM64A,MATN2,MPP2,ARAP1,AGBL5,SFMBT1,CABIN1,CDK18,SAMD8,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,TCF25,TCTN2,GPR107,CAPN12,REPS2,CCDC110,RALBP1,CERCAM,ATP2C2,FAM78A,FTH1,TMEM19,FLT3,DDR1,ART5,CYP39A1,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,TRANK1,RNASEH2A,PDE4D,TSPAN1,OSBPL7,SULT2B1,DOCK4,COG2,FOXJ2,PANK1,CLSTN1,UTRN,KIF1C,PYGO1,ATP1B1,CBL,ITPR3,ATP10D,FZD7,DDOST,ACAD10,SLC27A3,COBL,MAMDC2,PRKAR1A,PLSCR4,DEPDC1,CBLL1,HERC5,NES,PLD2,DNAH3,EFNB1,FGF19,CKAP5,RASSF8,E2F7,CD9,CCDC82,FARP2,TGIF1,PDGFC,ALDH2,ARHGEF28,B3GNT2,LONRF3,ZC3H11A,TCFL5,ZKSCAN2,C2orf69,UBAC1,YES1,FOS,CDK5RAP1,DCTN6,ACADSB,DGCR2,SEC14L4,FGFR2,RIN3,ABCB1,ERAP1,WDR62,ESPL1,MELK,RGMA,FAF2,CRYM,VARS2,PLAC1,HTR1D,ADPRHL1,ZFYVE16,SIPA1L2,CDKL5,ANKFN1,TRPC1,BTBD3,CYP1B1,ASXL1,LAP3,ACBD3,ITCH,RGAG1,MAN2A2,GPRC5B,MADD,TDRD7,ZNF165,SP6,CHPT1,PCSK5,LASP1,PPP1R2,ZNF395,PPP1R12A,SERPINE2,BVES,ETV5,ABCG2,FAM81A,ADAMTSL4,QSOX2,CES2,PFKL,COL6A1,PRKCI,SRP54,LIMCH1,C10orf54,HLA-C,SLC12A2,CCDC88A,SNED1,ELK3,PODXL2,PDE5A,KIAA1109,NUBP1,C3orf58,STEAP1,MFSD7,RANBP9,INSR,TMEM30A,SPAG7,TOB1,COL16A1,RARG,AFAP1,CCNE2,LMO7,NCKAP5,PAX6,SORBS1,SOD2,COL18A1,IL27RA,EXT2,SAP130,ZNF687,REEP1,EPB41L4B,ECE1,NFKB2,EBAG9,SEPHS1,SOAT1,PTPRU,GLO1,CD40,TMTC2,ARHGAP35,SECTM1,TLE1,SPTBN5,ABCA1,KDELC2,GLIS3,FBLIM1,ENO2,ARHGEF11,TSPAN15,SHPRH,SERPINB9,COL4A5,INTS8,SBF1,NTAN1,ITGA2B,HDAC9,SYDE2,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,RRBP1,H2AFY,ARVCF,KANK2,SLC35A1,MYO5A,RBMS2,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,FAM73B,SWAP70,RND3,FIBCD1,CSGALNACT1,ARRB1,UACA,ZMIZ1,PLOD3,RAB3IL1,DOC2A,ACACB,TRIM24,IL15RA,ADD1,AASS,DNAJC3,MMADHC,FAM102B,DHX8,CNTROB,BARD1,PHF1,ZYX,TGFBR3,RGS12,PQLC2,CYP2S1,KLF3,FUT1,TUBG1,SEMA3G,TINAGL1,ACOX2,ODF2L,ERAP2,NWD1,SMARCA2,SPEF2,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,RELL1,PDPR,E2F8,GAB1,FAM169A,TMTC3,CYP2J2,STRN4,MERTK,LMNA,ELF3,DNPEP,CD22,NEK2,NCAM1,EPHX1,NAGPA,SLC37A1,KIF20A,TP53INP2,SPTLC2,DHX32,PTPRF,NCOA3,MTFMT,HTT,SETD3,ITPR1,DYSF,NDE1,TRPC3,XDH,ARHGAP11A,GRHL2,GALNT12,ACTR8,PKP2,IL13RA1,NUF2,PRSS22,APC2,TNFSF9,UHRF1BP1L,SCNN1A,SP100,DACT1,RTKN2,SCN3A,RNF169,ENPP4,FZD4,SYNE2,NUSAP1,CDCA2,PEX5,SLC9A6,WWTR1,SIPA1L1,INPP4B,PLEKHG1,RGS14,ARNT,TAOK2,TNRC6C,FARP1,PKN1,NEO1,DTX3L,CAPN2,ANK1,ADD3,SLC27A6,ARSG,CTSC,KCNK5,ADAM15,ZNF230,WWP1,AK3,SGCB,ITM2C,TPCN1,TMX1,HCN3,AMOTL2,CTNNAL1,RAPGEF2,ELOVL3,GRIN1,PLEKHA7,SNTB1,ABLIM2,GALNT3,KIAA0141,ACVRL1,NR1D2,CCDC6,ATXN7L3,ZFP30,ARFGAP3,FHL1,CENPE,NUP37,FOXA1,DCBLD1,AGRN,FAM199X,CUL4B,EPHA4,FHDC1,MCCC1,NDC80,CDIPT,HDAC6,SHC3,MKRN3,DDHD2,DUSP10,RGS5,TLN2,ANO4,S100A13,NEB,ZNF462,ESYT1,ANLN,IDH1,LHFPL2,CLCN2,VCP,OPTN,PLCH1,MFAP3L,TBC1D17,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,POMT1,GLCCI1,PRKAA2,CHCHD7,ASAH1,DOCK11,PGAP1,IL18R1,SSX2IP,RB1,DAZAP1,VASP,IGF1R,TMEM8A,PLCB2,PSMA5,ABCC1,CHSY3,WDR72,EIF2AK1,MOSPD3,COQ10A,H1F0,CSF1,ITGA7,LTBP2,ATP1B3,KCNAB3,NF2,UPF3B,FOXM1,DGKA,ZNF28,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,SDF4,C1orf116,PER2,RAD23A,SRPX,PLCG2,SRR,SCN2A,EGLN3,MINPP1,DVL2,SIRT1,TMTC1,FIGNL1,MYL12A,DUOX1,DNAJC10,RTN4RL1,PSMD3,ADAMTS14,ANXA9,AIFM3,NDST3,CMTM4,MAN2B2,GOLIM4,PACSIN2,CD63,MACC1,RUSC2,NKRF,JAG2,CHAC2,CRABP2,PPP2R3A,SLC9A2,CEP97,MAGEE1,BUB1,KLF9,CAMK2G,TLE6,DLGAP1,HMMR,IFITM3,AMFR,PPARA,TRIM35,AKAP3,BCAR1,BSDC1,MAPK8IP1,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,CDCA7L,ACADM,TBC1D4,NDFIP1,DIS3L,GAA,TTC39B,PPFIBP2,GATA3,PLXNA1,CCNB1,SLC20A1,ELMOD2,CENPN,CHST2,CTGF,ZFP36,IQCE,PRICKLE3,RGS3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,SMYD5,SNTB2,PBK,HSPA12A,MGAM,TNS1,AURKB,GALNT7,CCNF,SAV1,TP53I3,SPNS3,ULK2,SFXN1,AREG,PLK2,GNPTAB,DHTKD1,UNC5B,TANC2,RTN3,DDX58,CDK17,INPPL1,FRMD4A,DGKQ,SLC25A27,KIF23,NOTCH2,SLC1A3,KIAA1161,MECOM,ITGA3,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,PIKFYVE,TSPAN33,TMED2,EEF1D,IGSF3,DNAI1,EPB41L5,B3GNT7,KIAA1841,MFI2,TBC1D8B,PIP4K2C,KDM3A,GLT8D2,FRMD4B,DGKH,PRKAG2,SLC4A3,FGD6,MAP3K5,PKD1L2,PLA2G4A,PLEKHG3,SLC2A4,ARMCX3,NLRX1,TRIP10,RPS6KA1,IQGAP1,IRX4,RNF182,CD274,EGR3,AIFM2,GNB2,SLC25A35,APLP2,CYHR1,DOK4,TNPO2,CNNM4,PHKA2,LGMN,NR2C1,TBC1D10B,GPX4,MYO5B,SEC23A,SLC5A11,CDKN2AIP,CAPN6,TMEM43,TEP1,COX11,PRKCQ,C15orf39,H2AFV,SP4,NIN,EPHA10,FYN,PPP2R5A,SLC27A1,NRG1,ZC3H12B,MLKL,ATMIN,DENND5B,MRPS9,ARHGEF3,ANKRD13D,SLC16A14,CDCA3,CCNJL,APOBEC3H,CYB561,PNPLA5,TEAD3,TMCC3,C16orf59,PHF7,MGAT1,PTEN,CENPJ,SGK3,TRIM62,OSGIN1,NCOA2,SMC4,ARAP2,ERMAP,DENND1B,MPP1,FURIN,PARP4,MAMDC4,RCBTB2,PRDX3,CCDC69,CSTF2,GRIN2D,SLC25A38,NCAPG2,JARID2,EXPH5,EMX1,LTBP1,CPT2,CAMKK1,UBE2Z,TAF6L,DNER,KREMEN1,DENND2D,TMC1,SH3KBP1,CHPF,NKAIN3,ARHGEF10L,DPYSL2,PHTF1,CAPG,DLG1,ANKRD12,SUN3,MYH14,ARNT2,SLC39A10,TECR,PTPRE,RASGRP1,TDP1,ATL1,TRIM8,RNF165,ROR1,STK17B,TCN2,ARHGEF19,NEIL1,ZNF114,FASTKD1,TRIM45,IARS2,CCDC74B,ADIPOR1,APBA2,MIIP,PPP2R5D,PSMC1,CPPED1,STARD3NL,LRRFIP2,PEX6,ATP6V1E2,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FNIP1,KNTC1,NCEH1,PARD3B,GYLTL1B,AMDHD1,EGFR,MUM1L1,GLCE,GNAS,FECH,XKRX,ONECUT1,TSC1,SLC6A6,CGREF1,RHOBTB2,ALPK3,EGFL7,KIF12,FBXW5,PROM2,GAS2L1,ZSWIM5,FAM92A1,SLC2A8,MORC4,MICALL2,ARHGEF16,LRRC45,SS18,SETDB2,KHNYN,FRYL,SMO,STEAP3,RPN2,SCYL3,IGSF8,ERBB2IP,DOCK5,BHLHB9,OVOL1,CANT1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CDS2,JKAMP,FRMD6,ARMC7,LRP4,FAM134A,ZNF212,SNX13,ADORA1,GALNS,BRD7,TRIM3,HSPA13,IQGAP3,SUN2,ADAM17,RAB3B,ASPM,PHLDB3,NR4A1,OGDHL,SPAG1,MAP1B,KLHL2,C2orf70,PRCP,DHRS2,OTUB2,GLB1,ATP6V1C1,SOX8,L1CAM,ZNF596,SNPH |
| 6.046e-03 | -5.11 | regulation of response to external stimulus | biological process | GO:0032101 | 854 | 154 | 16441 | 2455 |
SIGIRR,TRIM24,TRIM5,EPHA4,XIAP,LMCD1,GATA3,IL18,NENF,PLXNA1,CAMK1D,PDGFB,MAP1LC3B,ELMOD2,CALM2,DAPK2,ZYX,PHYHIP,AP1M2,IL6ST,TSPAN6,DUSP10,SEMA3G,CTTN,APOBEC3G,METAP2,CD55,TNIP1,ITCH,PBK,BNIP3L,SLC35C1,F12,MYOM1,ABR,GPRC5B,HPSE,DNM1L,TRAF3IP1,MYLK,NOD2,MAPK13,HSPB1,F2RL1,TC2N,LZTS1,DDX58,PRKAA2,SEMA6B,SERPINE2,SCOC,UBASH3B,CALM3,TEC,SLC1A3,CORO1B,CALR,SPP1,RAC2,ZCCHC17,PIK3AP1,MEGF8,PAK2,FAM13B,PRKG1,ALPK1,CNGA1,PIKFYVE,WNT3A,MAPK7,QSOX1,KLK5,MICB,CALM1,ANO6,SHARPIN,PIP4K2C,CALCRL,NMT2,STX3,PTPRF,IL1R1,FNTA,SEMA4D,CSF1,OSMR,MDH1,STK39,KLK7,SEMA3A,TMEM173,DRD1,IL15,NLRX1,TP53,SLC7A2,EPM2A,IER3,CD46,PDGFA,NOV,FAM46A,ARTN,RALB,BCL6,IFIT1,F2R,SEMA3B,SIRT1,ENPP4,DMTN,PTGER4,PRKCQ,ATP1B1,CASP4,SOCS3,PTGS2,FYN,CDK19,CHMP4B,PLXND1,PINK1,HERC5,SELL,ETS1,GSTP1,HLA-A,CD109,GNB5,ADORA1,PTEN,IL17RA,KANK2,SYK,CASK,ADAM17,PSMB4,MPP1,PLAUR,GRIN1,VAMP3,PPARA,FXR2,BBS2,RGS9,SWAP70,NR1D2,SCG2,SLC35B3,FGF18,PPP2R3C,GPER1,FZD5,NDFIP1 |
| 6.049e-03 | -5.11 | regulation of lipid metabolic process | biological process | GO:0019216 | 276 | 57 | 16441 | 2455 |
PRKAA2,CCNC,ACACB,SORBS1,THRA,PNPLA2,PRKAA1,WDTC1,PDGFB,FLT3,FGF19,BMP2,PDGFA,RB1,ADORA1,IGF1R,CYR61,H2AFY,DAB2IP,TWIST1,GFI1,SIRT1,SOD1,AKT1,NRBF2,PIK3R1,PPARA,NPC2,PDK3,IDH1,TYSND1,PDHX,POR,PLIN5,GPLD1,SEC14L2,IRS2,PTGS2,LDLRAP1,PRKAG2,ATP1A1,MID1IP1,PPP2R5A,NR1D2,RBL1,PEX2,NR4A3,NOD2,SLC27A1,ADIPOR1,SAMD8,GPER1,CD81,PDPR,CNEP1R1,ABCG1,DLAT |
| 6.050e-03 | -5.11 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | 185 | 40 | 17758 | 2588 |
FARP1,EPAS1,BACE1,MCTP2,STRN4,CYB561,IL13RA1,TRIB2,DDR1,H1FX,APLP2,FAM46A,AOX1,TPST1,SORL1,TSPAN13,SCN3A,XKR8,GCNT1,RASGRF1,HN1L,CXorf57,UTRN,DOCK5,SESN1,EDNRA,GALNT3,NEIL1,SCG2,CDK19,PRCP,MMP17,PLK2,ABCB1,DTX4,PIK3C2B,SPRY4,NRGN,KLF7,FAM134B |
| 6.050e-03 | -5.11 | GSE3982_MAC_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_UP | 185 | 40 | 17758 | 2588 |
PLA2G4A,PRKAA2,ARHGEF3,CKAP2,CPT2,APOO,PTTG1,C6orf106,GTF3A,SLC20A1,SPSB1,PPP2R3A,SGPL1,TOP2A,DOPEY2,PSMD1,CCNA2,PAPSS1,GTF2F2,RPN2,DIXDC1,TACSTD2,MCCC2,FAH,UPF3A,SOCS5,NFE2L3,SOD1,SNAPC2,GNA11,FUCA1,DDOST,ACYP1,NEIL3,P4HA2,CSF1,PEX2,SPINT2,OTUB2,ERAP1 |
| 6.050e-03 | -5.11 | GSE27786_NKCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_NKCELL_VS_NEUTROPHIL_DN | 185 | 40 | 17758 | 2588 |
PLEKHG3,DDX58,PPP4R4,KLK10,GRIK2,ARMC7,TMX4,NOV,ARHGAP42,RINL,LMAN2L,MCF2L,ICAM5,GALNS,PRC1,TFAP2A,RP2,SEMA3G,OSBPL7,TIAM1,AMOTL2,SYPL1,UFD1L,CASK,ACVR1C,NR3C1,STRADB,EMP3,RANBP9,EDNRA,KLHL2,BANK1,FA2H,PLK2,TMC5,TDRD7,ADIPOR1,ARPC2,CPEB2,E2F8 |
| 6.050e-03 | -5.11 | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP | MSigDB lists | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP | 185 | 40 | 17758 | 2588 |
BIN1,SLC35D2,CDK17,TRAPPC10,ATP9A,CAST,DGKA,DHX8,IL27RA,SBF1,BMP2K,GNS,LRRC45,ADD3,CA2,WDR44,CASC4,IFIT1,KLF9,RCAN3,TPCN1,OSGIN1,SULF2,TUBA4A,DDB2,TBC1D8B,OSTM1,OXR1,TTC7A,CBL,ABR,FYN,RAB11FIP2,KBTBD2,SLC35B3,PAPD5,ABCB1,ATP1B3,NRBP1,ESYT2 |
| 6.066e-03 | -5.11 | ETS_DOMAIN_3 | prosite domains | PS50061 | 28 | 10 | 11866 | 1802 |
ELK4,ELK3,ETS2,ETV5,ELF5,ELK1,ETV7,ETV4,ETS1,ELF3 |
| 6.070e-03 | -5.10 | Progesterone-mediated oocyte maturation | KEGG pathways | hsa04914 | 87 | 23 | 6908 | 1076 |
PLK1,CPEB4,AKT1,RPS6KA1,PIK3R1,PKMYT1,CCNB1,CDC25C,PRKACA,CDK1,CCNA2,RPS6KA2,IGF1R,CCNB3,PIK3CA,BUB1,MAPK13,MAPK11,PIK3CD,CCNB2,CPEB2,RPS6KA3,MAPK12 |
| 6.070e-03 | -5.10 | Progesterone-mediated oocyte maturation | KEGG pathways | ko04914 | 87 | 23 | 6908 | 1076 |
PLK1,CPEB4,AKT1,RPS6KA1,PIK3R1,PKMYT1,CCNB1,CDC25C,PRKACA,CDK1,CCNA2,RPS6KA2,IGF1R,CCNB3,PIK3CA,BUB1,MAPK13,MAPK11,PIK3CD,CCNB2,CPEB2,RPS6KA3,MAPK12 |
| 6.075e-03 | -5.10 | V$E47_01 | MSigDB lists | V$E47_01 | 242 | 50 | 17758 | 2588 |
IER5L,SCN5A,SORBS1,HOXB7,TRIP10,KLHL13,DDIT4L,THRA,ITGA6,CACNA2D2,GABRG2,CALM3,SORBS3,CAMK1D,PDGFB,FLT3,PSIP1,CYP26A1,PICK1,CALM2,ITGA3,MGAT1,CASC4,SH3BP1,PLK4,DUSP10,EPB41L4B,CITED2,MYLIP,TSPAN33,CAMK2G,MAP3K3,DPYSL5,TRIM8,CORO2A,CALM1,RGAG1,GNA11,GNAS,ONECUT1,IDE,RBL1,CORO1C,NETO2,NR4A3,SH3GLB2,EFNA1,DRP2,DEF6,IRF1 |
| 6.075e-03 | -5.10 | IVANOVA_HEMATOPOIESIS_STEM_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL | 242 | 50 | 17758 | 2588 |
INPPL1,TCF25,NFKBIE,TCTN2,SLC41A1,PRKAA1,ARL4C,PPFIBP2,GATA3,COL18A1,NES,GALM,SDC1,DUSP5,NFAT5,CDK14,NKAIN3,ARHGAP42,ITGA3,TSPAN6,PRKG1,TRIM3,USP38,TSPAN13,ARNT2,SLC16A5,NCOA2,IGDCC4,SOCS5,SMARCA2,CTNNAL1,NR4A1,DUSP4,ULK2,NFIX,TRIM9,KCNMB4,MPRIP,DGCR2,PAPD5,NFKBIA,S100A5,NR4A2,PKD2,ZDBF2,GEM,HOOK1,IFIH1,SLC25A30,MAFF |
| 6.077e-03 | -5.10 | innate immune response | biological process | GO:0045087 | 1014 | 180 | 16441 | 2455 |
UNC93B1,TNK1,TXN,LGR4,TRIM5,CUL1,NRG2,GATA3,PSME1,ITPR2,PDGFB,SPTB,TRIM68,CALM2,PSMD1,RPS6KA2,CTNNB1,SHC3,ELMO2,PSMC2,PIK3CA,IRF2,PIK3CD,APOBEC3G,IL1RAP,RASGRP1,NLRP4,CD55,TRIM8,ITCH,USP18,CASP9,CR2,AGO4,PRKAR2B,F12,RNF19B,PLCG1,LIMK1,NOD2,RNASEL,F2RL1,PSMC1,GAB1,PPP2R5D,DDX58,LGALS3,HLA-E,RASA2,HLA-F,PSMD7,CALM3,TEC,NCKAP1,PHLPP1,DUSP5,RPL39,PAK2,DAPK1,HLA-C,NCAM1,MAPK7,ULBP2,PSMA5,MAPKAPK3,MICB,CALM1,ELK1,CYFIP2,IFIT3,PSMA4,EGFR,RASA1,MAPKAPK2,PELI2,PHLPP2,CSF1,NFKBIA,RAET1L,ITPR1,NLRC5,ARPC2,MAP3K5,IFIH1,JAK3,IFI6,RPS6KA3,TMEM173,IRF1,SPRED1,NLRX1,TUBB4B,RPS6KA1,PSME2,ERBB2,P2RX7,RASGRP3,BCL2L1,PRKACA,APOBEC3B,CD46,PDGFA,SP100,PLCG2,CDKN1B,DAB2IP,IFIT1,OAS3,RASGEF1A,LGMN,NFKB2,FRS3,MX1,RIPK2,AKT1,APOBEC3D,PRKCQ,ITPR3,DUSP4,SOCS3,IRS2,FYN,DDOST,JAK1,AXL,STAT6,PSMD3,STAT1,NRG1,IRF7,SPTBN5,PRKAR1A,OTUD5,TNRC6C,HSP90B1,TAB3,TRAF2,CTSB,HERC5,PSMD10,PLD2,APOBEC3H,FGF19,ICAM1,HLA-A,CXCL16,IRAK1,ADRBK1,PTEN,ADAM15,TRIM21,MAPK11,ERBB3,MAP3K7,CNPY3,SYK,TRIM62,CAMK2G,RASGRF1,PSMB4,IFITM3,RAPGEF2,NR4A1,PIK3R1,NUB1,GRIN1,FBXO9,TRIM35,YES1,FOS,TXK,BCL10,CTSL,HLA-B,FGFR2,FGF18,DTX4,UBE2D2,GRIN2D,GPER1 |
| 6.080e-03 | -5.10 | REACTOME_NETRIN1_SIGNALING | MSigDB lists | REACTOME_NETRIN1_SIGNALING | 38 | 12 | 17758 | 2588 |
PLCG1,FYN,RGMB,EZR,PITPNA,PRKCQ,NTN4,UNC5B,NTN1,TRPC3,RGMA,NEO1 |
| 6.080e-03 | -5.10 | KORKOLA_TERATOMA | MSigDB lists | KORKOLA_TERATOMA | 38 | 12 | 17758 | 2588 |
CENPA,ZWINT,DLGAP5,ZFP36,CDC20,EPS8,MRS2,AURKA,NUF2,NFKBIZ,CCNB1,CKS2 |
| 6.080e-03 | -5.10 | CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN | MSigDB lists | CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN | 38 | 12 | 17758 | 2588 |
DDB2,KIF14,PLAUR,CKAP2L,ARVCF,PIM1,CYFIP2,SEPT4,F2R,RNPEP,TCN2,FAS |
| 6.083e-03 | -5.10 | CTATGCA,MIR-153 | MSigDB lists | CTATGCA,MIR-153 | 202 | 43 | 17758 | 2588 |
LAMP1,EPHA4,MIER3,TESK2,MAPK4,TTYH3,SIX4,ZFYVE9,APLP2,ANK1,ZNRF2,SGK3,NPTN,RNF26,CITED2,TPCN1,CAMK2G,CKAP4,TRAK2,DPYSL5,SUN2,TAF5,PAPD7,ASXL1,PIK3R1,RNF165,FURIN,KBTBD8,GALNT7,CYFIP2,TP53INP2,RASA1,DCP2,KDSR,MFAP3L,SERTAD2,SLC4A4,FGFR2,SLC9A6,SH3BP4,KLF5,RPL22,GLCCI1 |
| 6.094e-03 | -5.10 | functioning | COSMIC cancer mutations | functioning | 1876 | 310 | 17775 | 2585 |
HECA,PPP4R4,PNISR,GRIK2,VANGL1,ATP8A1,RET,NRG2,LGI3,BAIAP3,CA8,KIF26A,GRM5,PQLC2,DNAH6,STIM1,RGS3,IL31RA,STEAP2,SNX16,ARMCX6,TIAM1,TIPARP,ERAP2,TUBA4A,SMARCA2,KIFC2,SNTB2,F12,COL12A1,ULK2,SGPP1,AHRR,SLC25A4,PTER,GNPTAB,MYLK,PPP2R4,NOD2,ANXA11,FRMD4A,TMTC3,ITGA6,CALB2,ZNRF3,TTYH3,DNPEP,FRY,SNX18,CD22,PRICKLE4,MEGF8,CADPS2,ALPK1,CNGA1,PIKFYVE,MOXD1,MYLIP,DGKG,GPR161,DNAI1,GCC2,QSOX1,KLK5,CEP89,MICB,WHSC1,TP53INP2,KDM3A,STK17A,NCOA3,AP1AR,ETS2,HTT,MATN2,FAM83D,FGD6,CABIN1,GDF11,DRP2,SERPINB1,ADAMTS16,ACTR8,BROX,CCDC110,IQGAP1,PKP2,APPBP2,UHRF1BP1L,MUC16,ST5,XYLT2,DAB2IP,ARL4D,RASGEF1A,RAB27B,OSBPL7,FLOT2,SCN3A,DOCK4,ERMP1,COG2,CAPN6,SYNE2,UTRN,TEP1,PRKCQ,ALCAM,ATP10D,EBF2,GIGYF1,NIN,DDOST,INPP4B,PNPLA6,RGS14,ARHGEF3,FARP1,NKX3-1,TAOK2,ATP9A,ESRP1,ZNF219,DNAH3,PDIA4,CKAP5,SNTA1,ZFX,OXCT1,CENPJ,CD9,ATP8B1,CASD1,SLC16A5,NCOA2,PVRL4,ADAMTS2,PDGFC,ARHGEF28,FMN1,TMEM221,GRIN1,CXorf57,PARP4,FURIN,CRTC2,NUCB1,RIN3,PGM2L1,OCLN,USP16,TLL2,ESYT2,JARID2,EXPH5,KIAA1462,FAF2,TMEM184B,AGRN,EPHA4,ARFGEF1,MPP5,KIF2C,ERP29,SPTB,SIPA1L2,CTNNB1,TSPAN6,MKRN3,DDHD2,ABCA2,POF1B,KIF22,ASH2L,MYH14,TLN2,MYRIP,BTBD3,NEB,OLFML2A,TDP1,MCTP1,TRIM8,CELSR2,SYNE3,ACBD3,ITCH,KLK6,PTGFRN,PLEKHG6,HPSE,MADD,ADIPOR1,SP6,EPB41L4A,CHPT1,RRAGD,ARAP3,LGALS3,PPP1R12A,HJURP,ETV5,NCKAP1,SAMD9,DOCK11,AIM1L,RB1,TNS3,KIAA0895,PFKL,FRAS1,KIF13B,PRKCI,EBF4,MTMR10,SRP54,WNT3A,PLCB2,PCDH1,FBXO8,ZSCAN12,EIF2AK1,KIAA1109,HEATR5A,RNF113A,BCL2L13,EGFR,NMT2,MUM1L1,PRX,ZDBF2,SHROOM2,FBXW5,NCKAP5,FOXM1,TP53,CCDC68,CCNL1,MICALL2,SYTL2,SS18,ZNF687,ARTN,SETDB2,FRYL,LHX6,FABP6,GOT1,RPN2,TMEM64,PDIA6,SULF2,TMTC1,ACO1,ERBB2IP,SNAPC2,FANCE,ARHGAP35,RTN4RL1,RBL1,TLE1,MAOA,SPTBN5,NDST3,KDELC2,BIN1,ANXA3,SORT1,TRAPPC10,ARHGEF11,MACC1,SH3D19,SHPRH,GTF3A,TRMT2B,HMGXB4,NRP2,SLC9A2,TOP2A,SNX13,CARD8,BMP7,LYPD6,MAGEE1,GALNS,TOX2,KIAA0319,TRIM21,ABCD1,HSPA13,IQGAP3,ATP2B1,MYO5A,HMMR,PSMB4,HMGN5,NR4A1,DPP9,MAML2,CAPNS1,COL7A1,FXR2,FNDC3A,TXNDC11,FIBCD1,UACA,ZMIZ1,L1CAM,ARHGEF4,GOLGB1 |
| 6.094e-03 | -5.10 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | 1876 | 310 | 17775 | 2585 |
HECA,PPP4R4,PNISR,GRIK2,VANGL1,ATP8A1,RET,NRG2,LGI3,BAIAP3,CA8,KIF26A,GRM5,PQLC2,DNAH6,STIM1,RGS3,IL31RA,STEAP2,SNX16,ARMCX6,TIAM1,TIPARP,ERAP2,TUBA4A,SMARCA2,KIFC2,SNTB2,F12,COL12A1,ULK2,SGPP1,AHRR,SLC25A4,PTER,GNPTAB,MYLK,PPP2R4,NOD2,ANXA11,FRMD4A,TMTC3,ITGA6,CALB2,ZNRF3,TTYH3,DNPEP,FRY,SNX18,CD22,PRICKLE4,MEGF8,CADPS2,ALPK1,CNGA1,PIKFYVE,MOXD1,MYLIP,DGKG,GPR161,DNAI1,GCC2,QSOX1,KLK5,CEP89,MICB,WHSC1,TP53INP2,KDM3A,STK17A,NCOA3,AP1AR,ETS2,HTT,MATN2,FAM83D,FGD6,CABIN1,GDF11,DRP2,SERPINB1,ADAMTS16,ACTR8,BROX,CCDC110,IQGAP1,PKP2,APPBP2,UHRF1BP1L,MUC16,ST5,XYLT2,DAB2IP,ARL4D,RASGEF1A,RAB27B,OSBPL7,FLOT2,SCN3A,DOCK4,ERMP1,COG2,CAPN6,SYNE2,UTRN,TEP1,PRKCQ,ALCAM,ATP10D,EBF2,GIGYF1,NIN,DDOST,INPP4B,PNPLA6,RGS14,ARHGEF3,FARP1,NKX3-1,TAOK2,ATP9A,ESRP1,ZNF219,DNAH3,PDIA4,CKAP5,SNTA1,ZFX,OXCT1,CENPJ,CD9,ATP8B1,CASD1,SLC16A5,NCOA2,PVRL4,ADAMTS2,PDGFC,ARHGEF28,FMN1,TMEM221,GRIN1,CXorf57,PARP4,FURIN,CRTC2,NUCB1,RIN3,PGM2L1,OCLN,USP16,TLL2,ESYT2,JARID2,EXPH5,KIAA1462,FAF2,TMEM184B,AGRN,EPHA4,ARFGEF1,MPP5,KIF2C,ERP29,SPTB,SIPA1L2,CTNNB1,TSPAN6,MKRN3,DDHD2,ABCA2,POF1B,KIF22,ASH2L,MYH14,TLN2,MYRIP,BTBD3,NEB,OLFML2A,TDP1,MCTP1,TRIM8,CELSR2,SYNE3,ACBD3,ITCH,KLK6,PTGFRN,PLEKHG6,HPSE,MADD,ADIPOR1,SP6,EPB41L4A,CHPT1,RRAGD,ARAP3,LGALS3,PPP1R12A,HJURP,ETV5,NCKAP1,SAMD9,DOCK11,AIM1L,RB1,TNS3,KIAA0895,PFKL,FRAS1,KIF13B,PRKCI,EBF4,MTMR10,SRP54,WNT3A,PLCB2,PCDH1,FBXO8,ZSCAN12,EIF2AK1,KIAA1109,HEATR5A,RNF113A,BCL2L13,EGFR,NMT2,MUM1L1,PRX,ZDBF2,SHROOM2,FBXW5,NCKAP5,FOXM1,TP53,CCDC68,CCNL1,MICALL2,SYTL2,SS18,ZNF687,ARTN,SETDB2,FRYL,LHX6,FABP6,GOT1,RPN2,TMEM64,PDIA6,SULF2,TMTC1,ACO1,ERBB2IP,SNAPC2,FANCE,ARHGAP35,RTN4RL1,RBL1,TLE1,MAOA,SPTBN5,NDST3,KDELC2,BIN1,ANXA3,SORT1,TRAPPC10,ARHGEF11,MACC1,SH3D19,SHPRH,GTF3A,TRMT2B,HMGXB4,NRP2,SLC9A2,TOP2A,SNX13,CARD8,BMP7,LYPD6,MAGEE1,GALNS,TOX2,KIAA0319,TRIM21,ABCD1,HSPA13,IQGAP3,ATP2B1,MYO5A,HMMR,PSMB4,HMGN5,NR4A1,DPP9,MAML2,CAPNS1,COL7A1,FXR2,FNDC3A,TXNDC11,FIBCD1,UACA,ZMIZ1,L1CAM,ARHGEF4,GOLGB1 |
| 6.096e-03 | -5.10 | Pkinase_C | interpro domains | IPR017892 | 29 | 10 | 18293 | 2672 |
RPS6KA2,AKT1,STK38,RPS6KA1,CIT,SGK3,SGK1,PRKCQ,PKN1,RPS6KA3 |
| 6.096e-03 | -5.10 | Ets_dom | interpro domains | IPR000418 | 29 | 10 | 18293 | 2672 |
ELK4,ELK3,ETS2,ETV5,ELF5,ELK1,ETV7,ETV4,ETS1,ELF3 |
| 6.112e-03 | -5.10 | CENTROSOME | MSigDB lists | CENTROSOME | 57 | 16 | 17758 | 2588 |
PLK1,PCGF5,DLGAP5,UXT,KIF20B,CNTROB,SAC3D1,NIN,CKAP5,TOP2A,CNTRL,MAP3K11,NEK2,CEP41,NDE1,ESPL1 |
| 6.112e-03 | -5.10 | JI_RESPONSE_TO_FSH_DN | MSigDB lists | JI_RESPONSE_TO_FSH_DN | 57 | 16 | 17758 | 2588 |
PACSIN2,ADD1,ITGA6,RAB6A,CCNF,RANBP9,KIF5B,TOP2A,GNS,RB1,JAK1,PAK2,OSMR,TMBIM6,ARF6,DUSP1 |
| 6.112e-03 | -5.10 | GNF2_CDC27 | MSigDB lists | GNF2_CDC27 | 57 | 16 | 17758 | 2588 |
GCLM,ERMAP,GCLC,BLVRB,BNIP3L,EIF2AK1,UBAC1,SPTB,RAD23A,FECH,ANK1,CA2,FBXO7,DCUN1D1,MINPP1,TRAK2 |
| 6.112e-03 | -5.10 | PID_TXA2PATHWAY | MSigDB lists | PID_TXA2PATHWAY | 57 | 16 | 17758 | 2588 |
RHOA,AKT1,PRKCQ,YES1,PRKACA,ADRBK2,GNA11,EGFR,ICAM1,FYN,GNB5,ADRBK1,PRKG1,MAPK11,PLCB2,SYK |
| 6.120e-03 | -5.10 | STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_UP | MSigDB lists | STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_UP | 77 | 20 | 17758 | 2588 |
TGIF1,CDK17,SNTB2,DNAJC3,ARHGEF7,EPHA4,FHL2,STMN3,KLK6,CCNL1,SLC1A3,TRIB2,SOCS3,WDFY1,AREG,KIAA1804,OSCP1,IFIT1,TTC39C,ATP2B1 |
| 6.124e-03 | -5.10 | MAP2K3 (mitogen-activated protein kinase kinase 3) | protein interactions | 5606 | 31 | 11 | 16036 | 2547 |
MAP3K3,TAOK2,PPP2R4,ARRB1,MAP3K5,PKN1,ELK1,PLCB2,MAPK8IP1,EGFR,MAPK12 |
| 6.124e-03 | -5.10 | ACP1 (acid phosphatase 1, soluble) | protein interactions | 52 | 31 | 11 | 16036 | 2547 |
RPL12,FYN,INSR,CTNNB1,SFMBT1,GOT1,PITPNA,BARD1,PCBP1,EGFR,ABRACL |
| 6.124e-03 | -5.10 | negative regulation of ERK1 and ERK2 cascade | biological process | GO:0070373 | 51 | 15 | 16441 | 2455 |
TNIP1,DLG1,NDRG2,ARRB1,EZR,DAB2IP,GPER1,SPRY4,RGS14,GSTP1,FBLN1,C3orf33,RANBP9,SPRY2,DUSP1 |
| 6.139e-03 | -5.09 | negative regulation of cell motility | biological process | GO:2000146 | 203 | 44 | 16441 | 2455 |
TCAF1,ARAP3,NF2,ADGRG1,PKP2,GATA3,VASH1,FBLN1,CORO1B,NOV,SVBP,PDCD10,TIMP1,ADORA1,SP100,PTEN,ADAM15,DAB2IP,TACSTD2,CITED2,CYP1B1,PTPRU,ACVR1C,PTGER4,RGCC,ARHGDIB,EPHA1,ILK,DAG1,RHOB,ABR,DPYSL3,AP1AR,PTPRJ,ACVRL1,CORO1C,SPINT2,RAP2C,EGFL7,NRG1,ARHGAP4,SEMA3A,MIIP,DRD1 |
| 6.145e-03 | -5.09 | Androgen receptor signaling pathway | WikiPathways | WP138 | 88 | 24 | 4455 | 729 |
SIRT1,RHOA,RUNX2,BMF,AKT1,DSTN,PIK3R1,ETV5,FHL2,AES,RHOB,EGFR,PAK6,PIAS3,CALR,CCND1,RB1,NCOA3,CTNNB1,PTEN,HDAC1,ZMIZ1,NCOA2,NR2C2 |
| 6.148e-03 | -5.09 | SUN | prosite domains | PS51469 | 6 | 4 | 11866 | 1802 |
SUN1,SUN2,SUN3,SUCO |
| 6.148e-03 | -5.09 | PET | prosite domains | PS51303 | 6 | 4 | 11866 | 1802 |
PRICKLE1,PRICKLE3,PRICKLE4,LMCD1 |
| 6.148e-03 | -5.09 | FBA | prosite domains | PS51114 | 6 | 4 | 11866 | 1802 |
FBXO44,FBXO6,FBXO27,FBXO2 |
| 6.168e-03 | -5.09 | FERM_M | pfam domains | PF00373 | 46 | 14 | 16629 | 2504 |
FRMPD3,EPB41L5,PLEKHH2,FARP1,FRMD4A,NF2,FRMD6,EZR,EPB41L4B,TLN2,EPB41L4A,MYLIP,FARP2,FRMD4B |
| 6.186e-03 | -5.09 | TUBA4A (tubulin, alpha 4a) | protein interactions | 7277 | 150 | 36 | 16036 | 2547 |
TAOK2,ENO2,TUBB4B,CUL4B,CALB2,TP53,CCNJL,CUL1,DNAJB11,RACGAP1,HDAC6,ICAM1,RBM23,PSMD1,TUBG1,ERBB3,SIMC1,SYK,PLK1,KLK5,B3GNT2,CDC20,IGSF8,PKM,ILK,BCAR1,ANTXR1,EGFR,MAGED2,FYN,DCUN1D1,ARRB1,STARD13,HSPB1,CD81,CTDSP1 |
| 6.188e-03 | -5.09 | Post NMDA receptor activation events | REACTOME pathways | R-HSA-438064 | 37 | 12 | 8202 | 1235 |
CALM2,RASGRF1,RPS6KA2,CAMKK1,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D,PRKACA,RPS6KA3,CAMK2G |
| 6.189e-03 | -5.08 | Transport to the Golgi and subsequent modification | REACTOME pathways | R-HSA-948021 | 95 | 24 | 8202 | 1235 |
SEC23A,TRAPPC10,MAN1A2,MGAT4B,COL7A1,CTSZ,MCFD2,B4GALT4,MAN2A2,FUCA1,NAPG,SERPINA1,MGAT1,AREG,CTSC,MGAT4A,LMAN2L,FUT8,B4GALT3,LMAN1,TFG,PPP6R1,MGAT5,TMED2 |
| 6.193e-03 | -5.08 | V$SMAD3_Q6 | MSigDB lists | V$SMAD3_Q6 | 225 | 47 | 17758 | 2588 |
LTBP1,ACVR1,MRC2,EPHX4,ATP6V1E2,TAF6L,MORF4L2,CRABP2,TEAD3,IL17RB,KCTD15,ST5,ANKS6,FRY,ANKS1B,GPC3,BHLHE41,LHX6,SERINC2,RFX5,PDE4D,ZRANB1,BTBD3,MYT1,PLEKHA6,WNT10B,PELI3,SAV1,KDM3A,RNF19B,NIN,TMEM164,ARHGEF19,PLEKHH2,SYT7,MAP2,H1F0,C1orf21,NXPH4,FAM117A,GRIN2D,ANXA9,RUSC1,KLF7,JARID2,DOCK9,DMPK |
| 6.194e-03 | -5.08 | LEIN_OLIGODENDROCYTE_MARKERS | MSigDB lists | LEIN_OLIGODENDROCYTE_MARKERS | 72 | 19 | 17758 | 2588 |
PLEKHG3,MBP,UGT8,NDRG1,ANLN,SEPT4,SEPP1,PLEKHB1,FRMD4B,TMEM63A,CA2,FA2H,SLC44A1,ABCA2,SGK1,TMBIM6,CD81,SERPINB1,CERS2 |
| 6.194e-03 | -5.08 | GRABARCZYK_BCL11B_TARGETS_UP | MSigDB lists | GRABARCZYK_BCL11B_TARGETS_UP | 72 | 19 | 17758 | 2588 |
RECQL,NQO1,AGPS,DENND1B,S100A4,PIK3R1,AK4,PRKAR2B,TRUB1,ZDHHC21,TRAM2,SCARB2,JAK1,TIMP1,AIM1,SLC35A1,APOBEC3G,TMEM173,RPS6KA3 |
| 6.195e-03 | -5.08 | PDK2 (pyruvate dehydrogenase kinase, isozyme 2) | protein interactions | 5164 | 12 | 6 | 16036 | 2547 |
SGK1,ISOC2,AKT1,HTT,PDHX,DLAT |
| 6.195e-03 | -5.08 | Cep72 (centrosomal protein 72) | protein interactions | 74470 | 12 | 6 | 16036 | 2547 |
PPP1CB,PPP1R12A,PPP1R2,PPP1R10,CDK1,SH2D4A |
| 6.195e-03 | -5.08 | Ppp2r1a (protein phosphatase 2, regulatory subunit A, alpha) | protein interactions | 51792 | 12 | 6 | 16036 | 2547 |
FECH,PPP2R5A,SGOL1,PPME1,PPP2R2D,PPP2R5D |
| 6.201e-03 | -5.08 | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | MSigDB lists | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | 62 | 17 | 17758 | 2588 |
PLK1,CEP70,TUBB4B,PRKAR2B,CCNB1,PRKACA,CDK1,CKAP5,CNTRL,CENPJ,TUBGCP6,PLK4,NEK2,TUBG1,SSNA1,CEP41,TUBA4A |
| 6.201e-03 | -5.08 | V$AHR_01 | MSigDB lists | V$AHR_01 | 62 | 17 | 17758 | 2588 |
NR3C1,VAMP3,TP53,HMG20B,RUNX3,MORF4L2,PRX,PAK6,CCND1,ZFX,CYP1A1,CAMK2N2,H1F0,LMO4,DPYSL2,ITPR1,NCAM1 |
| 6.204e-03 | -5.08 | protein transport | biological process | GO:0015031 | 1213 | 212 | 16441 | 2455 |
EXPH5,UNC93B1,FAF2,GRIK2,ARFGEF1,TAP1,GATA3,UBE2Q1,TRAPPC8,SYTL4,HDAC6,SNX9,NUP62CL,ERP29,PICK1,ZFYVE16,NAPG,RAB15,AP1M2,NUP210,RABEP2,LMAN2L,DNM2,SNX16,RAB20,RP2,CTTN,TRAM1,MYRIP,S100A13,LAMP2,VPS11,KDELR3,ARFRP1,KIF13A,ICMT,MCFD2,RNF19B,RAB2B,ARF4,VCP,OPTN,TRAM2,TBC1D17,UEVLD,GNPTAB,RAB11FIP1,NOD2,KPNA2,ARF6,APBA2,F2RL1,NXT2,PCSK5,GGA1,PEX6,SEC61G,RAB23,ATP6V1E2,RAB6A,APBA1,FAM21C,PGAP1,LMNA,ATG4A,CALR,DOPEY2,SNX18,RINL,FRAS1,RPL39,NECAB3,KIF13B,FBXO7,EXOC8,PRKCI,SRP54,SORL1,CADPS2,SYTL3,NUP85,TMED2,RIMS2,SNX7,KDELR1,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,KIF20A,BTN3A2,STRADB,CALCRL,GOLT1A,ZDHHC3,RHOB,STX3,GNAS,AP1AR,SCARB2,TIMM8A,HTT,ZDHHC20,NFKBIA,RAB31,ZDHHC7,CTSA,LTBP2,HOOK1,JAK3,TOB1,NUP58,SNX30,DRD1,EHD1,MTM1,C5orf30,TP53,MVB12B,BCAP31,ZFYVE9,APPBP2,SYTL2,ATP6V0B,SVBP,ZDHHC12,BCL6,ZDHHC23,TNPO2,STEAP3,RPN2,IFIT1,LMAN1,RAB27B,ARL4D,F2R,SNX10,ATG4D,CHP1,MYO5B,SNX8,SEC23A,SEC61B,AKT1,COG2,DMTN,VPS4B,AP5M1,SLC11A2,ATP1B1,RAB38,SNX12,ATP10D,DAG1,PEX5,STX10,DDOST,PEX2,CHMP4B,RAB29,RPL22,ABCA1,COPG1,TTC8,HSP90B1,TAOK2,CD63,BTN3A1,PDIA3,IFT27,AIP,VPS26A,ZDHHC21,PDIA4,SNX13,ANK1,ADORA1,MLPH,PPP1R10,FAM160A2,RRBP1,TRIM3,CPLX1,SYK,RPGR,CAMK2G,MYO5A,HES1,RAB3B,LCA5,DENND1B,PIK3R1,EIF5A2,VAMP3,PRICKLE1,RAB3IP,NEURL1B,BBS2,RGPD5,RPL12,MAMDC4,RAB11FIP2,SCG2,ARFGAP3,ARRB1,SPCS3,ATP6V1C1,CEP41,NUP37,RAB3IL1,ABCG1 |
| 6.205e-03 | -5.08 | PLASMA_MEMBRANE | MSigDB lists | PLASMA_MEMBRANE | 1389 | 235 | 17758 | 2588 |
LAMP1,BCAM,ACVR1,SSH1,GRIK2,SLC25A13,EPHA4,F11R,SYTL4,ITPR2,CACNB4,DNER,SLC20A1,SDC1,SLC9A3R2,PICK1,GRM5,HTR1D,CALM2,EPCAM,ZYX,CTGF,CTNNB1,TM9SF2,STIM1,IL6ST,SLC46A1,DLG1,STEAP2,FUT1,TRPC1,CLDN4,TACSTD2,IL10RB,CPE,IL1RAP,SGCE,SOD1,CD55,ACVR1C,SNTB2,ROR1,SLC17A5,SLC25A5,EDNRA,HS6ST1,KCNMB4,SLC25A4,KCNK1,ATP7B,MADD,NOD2,TMEM8B,ARF6,SLC31A2,F2RL1,CD99,PRSS8,LGALS3,FXYD3,CALM3,SORBS3,NOTCH2,MERTK,IL18R1,TSPAN7,ITGA3,LYPD3,KCNN4,SLC16A6,ICAM5,OPN3,SORL1,CD70,CACNA1D,CNGA1,FAM84B,PIKFYVE,NCAM1,SLC12A2,NUP85,CCDC88A,ABCC1,TRAK2,FADS2,PODXL2,PCDH1,MMD,MFI2,RGMB,PTPRH,CALM1,CALCRL,EPHA1,STEAP1,GNA11,EGFR,STX3,RHOB,GNAS,PTPRF,MMP15,IL1R1,GABRD,SCARB2,INSR,SLC4A4,PVRL2,COL13A1,ITPR1,SLC4A3,MPP2,OSMR,DYSF,EFNA1,ATP1B3,TRPC3,SHROOM2,DRD1,SLC2A4,SORBS1,NF2,IL15,ST14,SLC2A8,CD82,HDAC11,PKP2,P2RX7,IL13RA1,MRAS,IL27RA,SLC7A2,APC2,FLT3,DDR1,KTN1,BCAP31,SYTL2,CD46,CDH1,NOTCH3,EPHB4,F2R,GCA,AKT1,PTPRU,UTRN,SLC11A2,ERBB2IP,ATP1B1,ITPR3,CBL,CD40,DAG1,FZD7,FYN,ATP1A1,RTN4RL1,PTPRJ,SHROOM3,PTK7,AXL,MMP17,EFNA5,HS3ST3B1,AIFM3,LIFR,ABCA1,MPZL1,CD63,TSPAN15,BACE1,FLOT1,GABRG2,SELL,CYB561,PLD2,TGFBR1,JAG2,NUCB2,KCNC4,EFNB1,SIRPA,ICAM1,FZD6,XPR1,RND1,NEO1,M6PR,IL17RB,ADORA1,ITGB8,MAGEE1,KCNK5,GPC3,ATP8B1,TMBIM6,TSPAN13,ERBB3,SGCB,SYK,SLC16A5,SLC35A1,ATP2B1,P2RX4,SYPL1,ADAM17,CASK,ERMAP,PLSCR1,IFITM3,MPP1,PLAUR,GRIN1,SNTB1,AIF1L,BCAR1,RNPEP,CD83,BCL10,CNTNAP1,TMEM50B,LDLRAP1,PROM1,ACVRL1,PGRMC1,RYK,ARRB1,PKD2,FZD5,CD81,OCLN,ABCG1,CD33 |
| 6.221e-03 | -5.08 | AURKA (aurora kinase A) | protein interactions | 6790 | 223 | 50 | 16036 | 2547 |
TNRC6C,DLGAP5,TUBB4B,SEC61G,CNOT8,DCAF7,PTTG1,NDC80,SOD2,TP53,FTH1,NUF2,KIF2C,HDAC6,PRKACA,SNX9,BARD1,CKAP5,TP73,SNX18,OSBPL3,PASK,TFAP2A,CTPS1,SORL1,TUBG1,PPP1CA,HSPA2,PSMA5,HMMR,PLK1,PSRC1,TACC1,CDC20,AMER1,EZR,AURKB,BORA,RASA1,NIN,CNOT2,RPL12,NFKBIA,TCEAL4,PPP1CB,AURKA,CTNND1,ARPC2,RPL22,WDR62 |
| 6.224e-03 | -5.08 | BROWNE_INTERFERON_RESPONSIVE_GENES | MSigDB lists | BROWNE_INTERFERON_RESPONSIVE_GENES | 67 | 18 | 17758 | 2588 |
MX1,IL15RA,PLSCR1,IL15,HLA-F,TAP1,GMPR,IFIT3,TYMP,SP100,NMI,TDRD7,STAT1,TRIM21,IRF7,APOBEC3G,IFI6,MELK |
| 6.232e-03 | -5.08 | ACEVEDO_LIVER_CANCER_DN | MSigDB lists | ACEVEDO_LIVER_CANCER_DN | 510 | 95 | 17758 | 2588 |
PLEKHG3,LAMP1,ACACB,AVPI1,TCF25,TMEM86B,PPFIBP2,NDRG2,VARS2,TAF6L,HDAC6,OAT,SLC20A1,PHLDA1,CYP39A1,IER3,CCND1,RCN1,APLP2,FAM46A,ZFP36,FOSB,ESPN,PHKA2,SOD1,CXXC5,CAPN6,ITCH,LYRM1,CDA,EZR,F12,SGPP1,SFXN1,AGPAT2,C19orf66,WFS1,PDXK,RAP1GAP,PSMC1,ARNT,MAN2B2,KLF2,PCOLCE,PINK1,PLSCR4,ZNF395,CTSB,SDC4,PBX3,GSTP1,DUSP5,SIRPA,CXCL16,MLPH,CYR61,FAM160A2,KIF13B,COL6A1,PCYOX1,UBE2J1,TMBIM6,HMGCL,AK3,SLC35A1,SHMT1,ALDH2,WDR72,OGDHL,FURIN,EIF2AK1,SRSF5,BCL2L13,FOS,SFXN5,GNA11,CRISPLD2,FUCA1,NUCB1,MAMDC4,PRKAG2,RPL12,ETS2,ACADSB,FAAH,SEC14L4,RND3,NFKBIA,DGAT2,NR4A2,SH3BGRL2,HOOK1,CD81,IRF1,DIS3L |
| 6.250e-03 | -5.08 | SH3_2 | interpro domains | IPR011511 | 57 | 16 | 18293 | 2672 |
DOCK4,SORBS1,CASK,MACC1,ARHGEF7,SH3D19,MPP1,RUSC2,MPP5,SH3RF2,SH3D21,TJP3,ARHGEF37,MCF2L,MPP2,SH3BP4 |
| 6.261e-03 | -5.07 | GSE7460_CD8_TCELL_VS_TREG_ACT_DN | MSigDB lists | GSE7460_CD8_TCELL_VS_TREG_ACT_DN | 191 | 41 | 17758 | 2588 |
ARHGAP11A,NDC80,ERI2,CDCA3,MIER3,C1orf198,SNN,SSX2IP,RB1,GRHL1,SHC3,NEK2,EXOC8,TNFRSF18,LRP11,MYBL1,TIAM1,TMX1,CPD,SOD1,PTPN9,VAMP3,UBE2A,PRKAR2B,NUSAP1,AURKB,PDK3,ANLN,TMTC2,PSMA4,C4orf27,KLHL2,UEVLD,RAB11FIP2,AURKA,NFKBIZ,SPCS3,NUP37,GEN1,MELK,NXT2 |
| 6.261e-03 | -5.07 | ALONSO_METASTASIS_UP | MSigDB lists | ALONSO_METASTASIS_UP | 191 | 41 | 17758 | 2588 |
CD63,CTSB,MMADHC,PLA2G16,SEPP1,WEE1,APLP2,ATP6V0B,SLC30A6,SERINC2,CKS1B,ASH2L,FAIM,WBP5,TUBA4A,HMMR,ANO6,CDYL,SPA17,PDE5A,AK4,GGH,GLO1,NPC2,ANLN,KIF11,GOLT1A,LHFPL2,TP53I3,TMEM50B,IDE,RCBTB2,DCK,FAM114A1,UBE2D2,MDH1,ACADM,FHL1,ITGAV,HSPB1,PRKAR1A |
| 6.261e-03 | -5.07 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP | 191 | 41 | 17758 | 2588 |
PRSS8,CDK17,NF2,MPZL1,S100A11,ATP9A,CENPI,HMGN3,DUSP5,CHST2,ICAM1,FZD6,IER3,BTG3,SRPX,FUT2,LRRN2,CDK16,CLDN4,LOXL1,CDKN2D,LAMP3,P2RX4,HMMR,QSOX1,PRSS23,SLC39A8,PLAUR,SAT1,CCBL2,SLC11A2,SNTB1,CDK5R1,OPTN,IRS2,JAK1,ETS2,NFKBIA,AFAP1,IFI6,ATMIN |
| 6.261e-03 | -5.07 | GSE3982_DC_VS_TH2_DN | MSigDB lists | GSE3982_DC_VS_TH2_DN | 191 | 41 | 17758 | 2588 |
ARHGAP11A,SPC25,SERPINE2,DLGAP5,MRPS15,PTTG1,RAB23,GATA3,KIF2C,GPSM2,CENPN,IL18R1,CHST2,FANCI,CCNA2,PASK,ECI2,TWIST1,TSPAN13,TAGLN2,PDE4D,MAP3K7,DLG3,APOBEC3G,MPHOSPH9,TUBA4A,SEPHS1,HMMR,KIF20A,SYNE2,GINS4,ARHGAP35,SFXN1,DCTN6,GALNT3,PTGS2,DOLPP1,UBE2D2,FAM117A,NUP37,CCNB2 |
| 6.265e-03 | -5.07 | MAP2K6 (mitogen-activated protein kinase kinase 6) | protein interactions | 5608 | 27 | 10 | 16036 | 2547 |
MAPKAPK2,TAOK2,PTEN,STAT4,MAPK13,MAP3K7,PKN1,MAP3K5,PLCB2,MAPK12 |
| 6.269e-03 | -5.07 | Anchoring of the basal body to the plasma membrane | REACTOME pathways | R-HSA-5620912 | 90 | 23 | 8202 | 1235 |
PLK1,TCTN2,CEP70,B9D2,CEP89,TUBB4B,PRKAR2B,RAB3IP,PRKACA,CDK1,CKAP5,CEP162,CEP97,CNTRL,CENPJ,CEP78,NEK2,PLK4,TUBG1,SSNA1,CEP41,NDE1,TUBA4A |
| 6.270e-03 | -5.07 | REACTOME_MITOTIC_G1_G1_S_PHASES | MSigDB lists | REACTOME_MITOTIC_G1_G1_S_PHASES | 130 | 30 | 17758 | 2588 |
CCNE2,PSMB4,PSME2,MYBL2,PSMD7,CUL1,PSMD10,PSME1,PKMYT1,CCNB1,CDK1,PSMA4,PRIM1,CCND1,CDKN2C,RB1,WEE1,PCNA,PSMD1,CCNA2,RBL1,PSMD3,PSMC2,E2F1,CDKN1B,CKS1B,HDAC1,CDKN2D,PSMC1,PSMA5 |
| 6.273e-03 | -5.07 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP | 163 | 36 | 17758 | 2588 |
GLIS3,IER5L,NFKBIE,MRPS15,LFNG,DNAJC3,PSMD7,NES,SDC1,TNFRSF19,SLC9A3R2,B4GALNT1,TP73,SNX13,PPP1R16A,AIM1,PIK3CA,KANK3,KCTD3,ZC3H11A,IFITM3,COX11,SLC11A2,TCF7,ERBB2IP,FNDC3A,DDAH1,TIMP3,KLF12,FAT4,LRIG1,NETO2,SH3BGRL2,FAM149A,WBSCR27,RAB3IL1 |
| 6.319e-03 | -5.06 | human chr8p21.2 | chromosome location | human chr8p21.2 | 22 | 7 | 26250 | 2805 |
TRIM35,CDCA2,NKX3-1,DOCK5,PBK,SH2D4A,EBF2 |
| 6.319e-03 | -5.06 | human chr1p22.3 | chromosome location | human chr1p22.3 | 22 | 7 | 26250 | 2805 |
CYR61,LMO4,ODF2L,SSX2IP,MCOLN3,SYDE2,WDR63 |
| 6.322e-03 | -5.06 | MyD88 dependent cascade initiated on endosome | REACTOME pathways | R-HSA-975155 | 85 | 22 | 8202 | 1235 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,IRF7,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 6.322e-03 | -5.06 | Toll Like Receptor 7/8 (TLR7/8) Cascade | REACTOME pathways | R-HSA-168181 | 85 | 22 | 8202 | 1235 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,IRF7,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 6.324e-03 | -5.06 | tibia | COSMIC cancer mutations | tibia | 871 | 153 | 17775 | 2585 |
ILDR1,FAM199X,RET,NDC80,NDRG2,CA8,PIGL,DENND2D,NKAIN3,CTNNB1,CTGF,KIAA1107,P4HB,STIM1,ZFP36,PRICKLE3,POLL,PIK3CA,FUT1,PIK3CD,ANO4,CPE,NEB,CCDC74A,MARK1,TNS1,EAF2,SAV1,ANLN,IDH1,SESN1,COL12A1,PLCH1,TBC1D17,FASTKD1,ANKRD6,WIPI1,ATP7B,GNPTAB,MYLK,PRKCDBP,ARRDC1,POMT1,NR2C2,SCN5A,PPP1R2,LRRFIP2,FAM169A,TMTC3,QSOX2,RB1,IGF1R,CES2,FRAS1,KIF13B,MEGF8,BDH1,PRKG1,MAP3K9,SLAIN2,FAR2,ZMYM1,CCDC88A,GPR161,DNAI1,EPB41L5,MFI2,GYLTL1B,NFIB,EGFR,MUM1L1,GNAS,NT5C2,HTT,ITPR1,NLRC5,RHOBTB2,ZDBF2,EHD1,FBXW5,PKD1L2,NCKAP5,FOXM1,SUZ12,RALBP1,TP53,ERBB2,COL18A1,GRK6,TMEM170B,AIFM2,ART5,TNFSF9,SYTL2,SDF4,EPS8L2,RBM23,APLP2,TRANK1,REEP1,CNNM4,TMEM64,OSBPL7,EGLN3,DVL2,SNX8,CLCN3,AKT1,FIGNL1,UTRN,COX11,PTPRJ,DDOST,WWTR1,PLEKHG1,SPTBN5,SGOL1,ZMAT1,CDS2,CKAP5,CD109,LLGL2,ALPP,TMEM62,BMP7,CENPJ,RRBP1,FAM102A,H2AFY,TRIM3,TPCN1,FAM134C,MYO5A,PARP9,SUN2,NR4A1,MRS2,PPARA,PLEKHA7,DIAPH2,TRIM35,YES1,RNPEP,TRIM69,NR1D2,ACVRL1,FHL1,ITGAV,WDR62,PLOD3,ESPL1,ARHGEF4,SNPH |
| 6.350e-03 | -5.06 | Znf_LIM | interpro domains | IPR001781 | 72 | 19 | 18293 | 2672 |
LMO7,FBLIM1,LASP1,CRIP2,LMCD1,FHL2,PRICKLE1,MICALL2,ABLIM2,ZYX,PDLIM3,LIMK1,PRICKLE4,LMO4,PRICKLE3,LHX6,LIMCH1,FHL1,CSRP2 |
| 6.353e-03 | -5.06 | Factors involved in megakaryocyte development and platelet production | REACTOME pathways | R-HSA-983231 | 137 | 32 | 8202 | 1235 |
KIF3C,KLC2,TP53,KIF23,GATA3,RACGAP1,KIF2C,DOCK11,PRKACA,KIF26A,KIF5B,WEE1,GATA2,KLC3,IRF2,KIF22,AK3,DOCK4,KIF20A,HMG20B,PRKAR2B,KIF11,DOCK5,HDAC1,IRF7,CENPE,CBX5,MAFF,PRKAR1A,EHD1,DOCK9,IRF1 |
| 6.362e-03 | -5.06 | Endochondral Ossification | WikiPathways | WP474 | 65 | 19 | 4455 | 729 |
RUNX2,AKT1,CDKN1C,THRA,CALM1,SOX9,CALM3,RUNX3,PRKACA,CALM2,ENPP1,SPP1,TIMP3,IGF1R,BMP7,CTSV,FGF18,STAT1,CAB39 |
| 6.367e-03 | -5.06 | LIM | pfam domains | PF00412 | 70 | 19 | 16629 | 2504 |
LMO7,FBLIM1,LASP1,CRIP2,LMCD1,FHL2,PRICKLE1,MICALL2,ABLIM2,ZYX,PDLIM3,PRICKLE3,LIMK1,PRICKLE4,LMO4,LHX6,LIMCH1,FHL1,CSRP2 |
| 6.411e-03 | -5.05 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | 114 | 27 | 17758 | 2588 |
CASP3,TIMP2,IGFBP6,PLAUR,LITAF,TP53,ERBB2,EGR3,GSTP1,RHOB,FAS,BMP2,IL1R1,BTG3,WEE1,TIMP3,CASP7,TIMP1,PTEN,SHC3,IL6ST,BAX,DAPK1,CDKN1B,IGFBP2,RNASEL,HSPB1 |
| 6.411e-03 | -5.05 | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | 295 | 59 | 17758 | 2588 |
PLA2G4A,LTBP1,COL9A3,TRIM2,KLK10,PAX6,CKAP2,ITGA6,SOX9,ARL4C,SOD2,TP53,RAB23,MRAS,GPSM2,S100A2,CYP39A1,RAC2,MUC16,KCNN4,KCNK5,CD22,LMO4,ELF5,TAGLN2,ITM2C,MSH6,GPR161,LAMP3,CYP26B1,CASK,KLK5,CAPN6,TFAP2C,WHSC1,KLK6,RUNX3,NFIB,EGFR,PLEKHB1,RHEB,FZD7,NFIX,PTPRF,PTGS2,FYN,PLOD2,HOXA9,WWTR1,PGRMC1,BMP1,SERPINB5,CLIP4,KLF5,KLK7,APBA2,L1CAM,DLAT,RRAGD |
| 6.427e-03 | -5.05 | regulation of lymphocyte apoptotic process | biological process | GO:0070228 | 56 | 16 | 16441 | 2455 |
LGALS3,TSC22D3,TP53,P2RX7,PRKCQ,AURKB,CD274,BCL10,IRS2,PTEN,BAX,BCL6,FNIP1,RAG1,SLC39A10,JAK3 |
| 6.432e-03 | -5.05 | skin-head_neck-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-head_neck-carcinoma-Merkel_cell_carcinoma | 13 | 6 | 17775 | 2585 |
CTNNB1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 6.432e-03 | -5.05 | skin-lower_extremity-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-lower_extremity-carcinoma-Merkel_cell_carcinoma | 13 | 6 | 17775 | 2585 |
CTNNB1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 6.432e-03 | -5.05 | skin-upper_extremity-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-upper_extremity-carcinoma-Merkel_cell_carcinoma | 13 | 6 | 17775 | 2585 |
CTNNB1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 6.457e-03 | -5.04 | ganglioglioma | COSMIC cancer mutations | ganglioglioma | 25 | 9 | 17775 | 2585 |
TSC1,CTNNB1,AKT1,PTEN,PIK3CA,TP53,IDH1,GNA11,EGFR |
| 6.457e-03 | -5.04 | adnexal_tumour | COSMIC cancer mutations | adnexal_tumour | 25 | 9 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,MSH2,PIK3CA,TP53,IDH1,FLT3,EGFR |
| 6.457e-03 | -5.04 | biliary_tract-gallbladder-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-squamous_cell_carcinoma | 25 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 6.464e-03 | -5.04 | GSE17721_LPS_VS_POLYIC_4H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_4H_BMDM_UP | 197 | 42 | 17758 | 2588 |
DNAJB11,MPP5,SNTA1,VASP,IGF1R,IGSF9,PIK3AP1,FAM20C,RALB,SLC44A1,PIK3CA,PRKCI,EPHB4,IQGAP3,TSPAN1,NFKB2,PIKFYVE,SGCB,SNX10,PARP9,PPIF,B3GNT2,HMGN5,ACBD3,GRIN1,CALCRL,RAB38,FNDC3A,SPTLC2,ENDOD1,CCNB3,ETS2,ACYP1,PVRL2,ACAD10,PPP1CB,SFMBT1,STK39,SH3BGRL2,AHR,CBX4,RAD21 |
| 6.464e-03 | -5.04 | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_DN | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_DN | 197 | 42 | 17758 | 2588 |
NDRG1,CTSZ,MGST2,CAMK1D,TRIB2,LGALS3BP,SDF4,RABGGTA,EPCAM,ADD3,GNB5,FUT8,CD9,TNFRSF18,RFX5,IFIT1,EGLN3,MED30,GM2A,ALDH2,CXXC5,LONRF3,UBAC1,PTGFRN,FOS,ATP10D,CASP4,GABARAPL1,AMZ2,PLCG1,CD8A,CASP7,PLK2,CDCA5,FAM3C,STAT1,IRF7,NRGN,AHR,IRF1,ABCG1,XDH |
| 6.464e-03 | -5.04 | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP | MSigDB lists | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP | 197 | 42 | 17758 | 2588 |
BIN1,CMAS,LASP1,S100A11,TBC1D1,JKAMP,TAP1,TP53,IL27RA,SLC20A1,CMTM6,SIRPA,C16orf74,CDKN2C,ADRBK1,KLF3,NEK2,TNPO2,BRI3,ABCD1,TAGLN2,ERBB3,NTN1,MAPK7,B3GNT2,CXXC5,TNIP1,PLEKHO1,PIM3,ALCAM,C3orf58,LCP1,COL12A1,CMTM7,BCL10,IRS2,BOLA3,MPRIP,STAT1,RPL22,MAFF,CBX4 |
| 6.478e-03 | -5.04 | central_nervous_system-brain-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_I | 43 | 13 | 17775 | 2585 |
GNAS,TSC1,CTNNB1,AKT1,FGFR2,PTEN,RET,SMO,PIK3CA,TP53,IDH1,GNA11,EGFR |
| 6.482e-03 | -5.04 | ODONNELL_TFRC_TARGETS_UP | MSigDB lists | ODONNELL_TFRC_TARGETS_UP | 378 | 73 | 17758 | 2588 |
CASP3,ACACB,LGR4,GRIK2,TSC22D3,DGKA,NRG2,IL13RA1,FTH1,F11R,ZMYND10,CNTROB,FAM46C,KREMEN1,TNFSF9,MXD1,DAPK2,METTL7A,MYH14,TIAM1,APOBEC3G,SP5,MYO5B,SNX8,TRIM8,C3orf52,SAT1,TFAP2C,SESN1,STK17B,RHEB,WIPI1,PLK2,MYLK,HAGHL,INPP4B,MAOA,RBM43,CHPT1,BIN1,PRKAA2,SH3D21,ZNRF2,FAM20C,LLGL2,CALD1,FDXR,SGK1,PIM1,CITED2,NCAM1,MYLIP,TPCN1,DUSP1,IGSF3,DPYSL5,ALDH2,BTNL9,FHL2,MYEOV,NFIB,PLIN5,FAS,BTG1,TJP3,SERPINA1,RCBTB2,FGFR2,NR4A3,ARRB1,FBXO44,HOXB13,PER3 |
| 6.493e-03 | -5.04 | positive regulation of Ras protein signal transduction | biological process | GO:0046579 | 33 | 11 | 16441 | 2455 |
RASGRF1,ADGRG1,CSF1,ARRB1,ERBB2,NRG1,NOTCH2,RASGEF1A,F2R,F2RL1,RASGRP1 |
| 6.500e-03 | -5.04 | REACTOME_P38MAPK_EVENTS | MSigDB lists | REACTOME_P38MAPK_EVENTS | 13 | 6 | 17758 | 2588 |
MAPKAPK2,MAPK11,MAPK13,RALB,MAPKAPK3,MAPK12 |
| 6.500e-03 | -5.04 | TSAI_DNAJB4_TARGETS_UP | MSigDB lists | TSAI_DNAJB4_TARGETS_UP | 13 | 6 | 17758 | 2588 |
IFIT1,TIMP3,OAS3,IFIT3,SERPINB1,STAT1 |
| 6.500e-03 | -5.04 | WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_UP | MSigDB lists | WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_UP | 13 | 6 | 17758 | 2588 |
TLE1,ANXA3,PLOD2,PLK2,MYEOV,FLOT1 |
| 6.500e-03 | -5.04 | HASINA_NOL7_TARGETS_UP | MSigDB lists | HASINA_NOL7_TARGETS_UP | 13 | 6 | 17758 | 2588 |
CD99,CD70,TIMP2,TIMP1,PLAUR,NEO1 |
| 6.500e-03 | -5.04 | BIOCARTA_RB_PATHWAY | MSigDB lists | BIOCARTA_RB_PATHWAY | 13 | 6 | 17758 | 2588 |
RB1,WEE1,CDC25C,MYT1,CDK1,TP53 |
| 6.500e-03 | -5.04 | PHOSPHATASE_BINDING | MSigDB lists | PHOSPHATASE_BINDING | 13 | 6 | 17758 | 2588 |
SOD1,BCAR1,PPME1,PPP2R4,PIK3R1,DLG1 |
| 6.500e-03 | -5.04 | VACUOLAR_PART | MSigDB lists | VACUOLAR_PART | 13 | 6 | 17758 | 2588 |
LAMP2,SLC17A5,CTNS,CD63,LAMP3,ABCA2 |
| 6.500e-03 | -5.04 | LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_UP | MSigDB lists | LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_UP | 13 | 6 | 17758 | 2588 |
CCND1,VSIG10,DDAH1,PSRC1,CDC25C,ACOT7 |
| 6.502e-03 | -5.04 | ZHANG_TLX_TARGETS_60HR_DN | MSigDB lists | ZHANG_TLX_TARGETS_60HR_DN | 266 | 54 | 17758 | 2588 |
HSP90B1,HJURP,ERCC6L,RACGAP1,NUF2,KIF2C,CENPN,HMGXB4,FANCI,TOP2A,FAM111A,WEE1,CCNA2,DACT1,PLK4,KIF22,USP1,BUB1,NTN1,SLC12A2,TIPARP,TTPA,NUP85,MSH6,SMC4,LAMP3,HMMR,SOAT1,PLK1,SHMT1,FIGNL1,PBK,MYBL2,AK4,AURKB,ANLN,KIF11,SKA1,FRMD4B,PRIM1,SLC4A4,FAM64A,RBL1,DCK,ZMYND19,CDCA7L,CDCA5,ETAA1,SGOL1,NCAPG2,CCNB2,CBX5,E2F8,MELK |
| 6.503e-03 | -5.04 | PPP1CA (protein phosphatase 1, catalytic subunit, alpha isozyme) | protein interactions | 5499 | 277 | 60 | 16036 | 2547 |
SPRED1,TPRN,IBTK,PPP1R2,RASSF7,TP53,CUL1,UBE2Z,TGFBR1,BCL2L1,CCNB1,LBR,ZFYVE9,SYTL2,SH3RF2,RASSF8,ZFYVE16,RB1,PCNA,CDH1,PPP1R10,PTEN,DPYSL2,KIF13B,PPP1R16A,BAX,NEK2,SORL1,GYS1,ALDH7A1,PPP1CA,NCAM1,TFG,AKT1,UXT,KCTD20,CAPNS1,SCRIB,KIF13A,CDCA2,AURKB,SRSF5,LRRC1,ERBB2IP,PKM,CLCN2,CDK1,RANBP9,PIAS3,CCDC6,PPP2R4,WWTR1,PPP1CB,AURKA,HDAC1,MAL2,TANC2,MIIP,PRKAR1A,PHC1 |
| 6.513e-03 | -5.03 | telencephalon development | biological process | GO:0021537 | 226 | 48 | 16441 | 2455 |
ANXA3,EMX1,CASP3,SCN5A,NF2,ADGRG1,CNTNAP2,TP73,BMP2,FOXP2,CTNNB1,PTEN,TACC2,DPYSL2,KIF14,LHX6,ALDH1A3,SMO,BAX,DAB2IP,DIXDC1,ZBTB18,WNT3A,BTBD3,HES1,RHOA,TACC1,ASPM,GRIN1,TFAP2C,BBS2,NFIB,CDK5R1,EGFR,MDK,TSC1,FAT4,HTT,PHLPP2,DBI,RYK,NR4A3,NRG1,WDR62,NDE1,NRGN,SEMA3A,DRD1 |
| 6.517e-03 | -5.03 | centrosome cycle | biological process | GO:0007098 | 42 | 13 | 16441 | 2455 |
CTNNB1,CENPJ,TUBGCP6,NEK2,PLK4,AURKA,PKD2,CNTROB,NDE1,STIL,KIF11,CDK1,FBXW5 |
| 6.542e-03 | -5.03 | Alzheimers Disease | WikiPathways | WP2059 | 79 | 22 | 4455 | 729 |
CASP3,ADAM17,BACE1,CALM1,CASP9,TP53,GRIN1,CALM3,ITPR2,ITPR3,CDK5R1,FAS,CALM2,CAPN2,CASP7,IDE,ITPR1,GRIN2D,CACNA1D,PLCB2,CAPN1,CHP1 |
| 6.546e-03 | -5.03 | protein phosphatase regulator activity | molecular function | GO:0019888 | 76 | 20 | 16491 | 2452 |
PPP4R4,PPP1R2,CALM1,CALM3,PPP1R14C,PPP2R3A,SH3RF2,CALM2,PPP2R5A,PPP1R10,PPME1,PPP1R16A,PPP2R4,PPP4R1,RCAN2,CABIN1,RCAN3,PPP2R2D,PPP2R5D,DMPK |
| 6.549e-03 | -5.03 | WANG_BARRETTS_ESOPHAGUS_DN | MSigDB lists | WANG_BARRETTS_ESOPHAGUS_DN | 25 | 9 | 17758 | 2588 |
PRCP,CTSB,OVOL1,KLK7,KLK6,KLF5,EMP2,SERPINB1,LTA4H |
| 6.549e-03 | -5.03 | KINASE_INHIBITOR_ACTIVITY | MSigDB lists | KINASE_INHIBITOR_ACTIVITY | 25 | 9 | 17758 | 2588 |
CDKN2C,CDKN1C,DNAJC3,CDKN1B,HEXIM2,CDKN2D,MAPK8IP1,PKIA,SOCS3 |
| 6.549e-03 | -5.03 | NICK_RESPONSE_TO_PROC_TREATMENT_DN | MSigDB lists | NICK_RESPONSE_TO_PROC_TREATMENT_DN | 25 | 9 | 17758 | 2588 |
ZFX,CASP9,ETNK1,FLOT1,ERAP1,ITPR2,MAFF,ERAP2,ICAM1 |
| 6.549e-03 | -5.03 | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | MSigDB lists | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | 25 | 9 | 17758 | 2588 |
CD46,GAA,PRSS23,NQO1,NR3C1,PLAUR,COL18A1,IL13RA1,CTSD |
| 6.571e-03 | -5.03 | CASP1 (caspase 1) | protein interactions | 834 | 53 | 16 | 16036 | 2547 |
PLA2G4A,RIPK2,TRAF2,CAST,IL18,BCL2L1,KIF11,BCAP31,CASP4,EGFR,LMNA,CARD8,HTT,NOD2,TFAP2A,GAB1 |
| 6.575e-03 | -5.02 | Peptidase_C1A | interpro domains | IPR013128 | 13 | 6 | 18293 | 2672 |
CTSL,CTSZ,TINAGL1,CTSC,CTSB,CTSV |
| 6.575e-03 | -5.02 | Peptidase_C1A_C | interpro domains | IPR000668 | 13 | 6 | 18293 | 2672 |
CTSL,CTSZ,TINAGL1,CTSC,CTSB,CTSV |
| 6.576e-03 | -5.02 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | 93 | 23 | 17758 | 2588 |
LAMP2,THRB,ANXA3,PPP4R4,TRIM2,CYP2J2,CYB5R2,AMDHD1,EGFR,IL17RB,APLP2,CA2,CDH1,SERPINA1,LYPD6,BHLHE41,ISM1,MYLK,ELF5,SGK3,ACTA2,SORL1,CHPT1 |
| 6.586e-03 | -5.02 | MARTINEZ_RB1_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_TARGETS_DN | 511 | 95 | 17758 | 2588 |
LTBP1,TRIM2,KLK10,PAX6,FAM92A1,EPAS1,CRYM,ST14,NDRG1,THRA,RHBDL3,PTTG1,FHDC1,IRX4,PKP2,COL18A1,PLAC1,DDR1,SLC9A3R2,MAGOHB,PDGFA,NOV,GRHL1,SIVA1,ALDH1A3,SLC44A1,SMO,MYH14,ECE1,CTTN,MARCH2,EGLN3,SCARA3,TUBA4A,TMCC2,CLCN3,BAG4,MBP,CXXC5,CELSR2,CAPN6,SNTB2,PANK1,KIF1C,GLO1,ITPR3,FZD7,ACYP1,AGFG2,UNC5B,TC2N,COL9A3,LASP1,SORT1,CDKN1C,KLHL13,DAP,ESRP1,SOX9,TNFRSF19,GSTP1,SIRPA,FZD6,NEO1,CTNNBIP1,CALR,DOPEY2,DNPEP,CYR61,ATP5H,IGFBP2,ACAD8,SLC45A3,FAM134C,IGDCC4,NFE2L3,PDGFC,CTNNAL1,GCLC,LITAF,MYBL2,FOS,TP53INP2,NFIB,PITX2,PTPRF,FNTA,FA2H,PVRL2,PLOD2,CLIP4,LTBP2,ITGAV,SERPINB1,AHR |
| 6.590e-03 | -5.02 | KONDO_EZH2_TARGETS | MSigDB lists | KONDO_EZH2_TARGETS | 220 | 46 | 17758 | 2588 |
KLF2,ARHGEF3,TRIM2,ATP9A,CTSB,ITGA6,LMCD1,IL13RA1,DNER,ANO1,ZFX,CTGF,GALNS,KLF3,AOX1,ATP8B1,SORL1,SGK1,NTN4,KLF9,ACAD8,SCN2A,FAR2,LMAN1,SLC12A2,CPE,DOCK4,TMTC1,RAB3B,RGMB,SNTB2,STMN3,IFIT3,EGFR,TSC1,HLF,NIPSNAP3A,MYLK,WWTR1,SPRY4,FHL1,OSR1,ST3GAL1,IFI6,KDELC2,RRAGD |
| 6.592e-03 | -5.02 | V$TST1_01 | MSigDB lists | V$TST1_01 | 243 | 50 | 17758 | 2588 |
BMF,PAX6,GRHL2,IGFBP6,MACC1,KLHL13,CACNA2D2,INTS8,ZNF385B,LMNA,CDK14,PDGFA,AKIRIN1,KCTD15,SESN3,PPP1R10,CABP1,FLRT3,BHLHE41,PLCG2,TWIST1,PIM1,CITED2,NFKB2,BTBD3,SMARCA2,FBLN5,HN1L,MGAT4B,KIF1C,CCNF,G2E3,IRX3,PITX2,TTC12,FGFR2,MAP2,SIPA1L1,INPP4B,MPP2,PGRMC1,NR4A3,NXPH4,FAM117A,KLF5,NR4A2,C1orf43,TOB1,ANXA11,JARID2 |
| 6.593e-03 | -5.02 | WALLACE_PROSTATE_CANCER_RACE_UP | MSigDB lists | WALLACE_PROSTATE_CANCER_RACE_UP | 272 | 55 | 17758 | 2588 |
CCDC109B,PARP12,KIAA1462,IL15,CKAP2,HLA-E,HLA-F,SERPINB9,TMX4,ARL4C,TAP1,SELL,HERC5,BTN3A1,RASGRP3,HERC6,CCND1,RAC2,TYMP,CTNNB1,CTSC,IFIT1,HLA-C,MYBL1,APOBEC3G,RASGRP1,LAMP3,OLFML2A,MX1,IFITM3,AMFR,SEPT6,BTN3A2,RUNX3,IFIT3,DPYSL4,STK17B,EDNRA,CD83,OPTN,IRS2,HLA-B,CD8A,FYN,PDLIM3,ETS2,GPRC5B,NAT1,SECTM1,STAT1,NR4A3,ERAP1,NR4A2,IFI6,IRF1 |
| 6.596e-03 | -5.02 | TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | 43 | 13 | 17758 | 2588 |
INSR,IGF1R,PTK7,AXL,RYK,PDGFRL,ERBB3,ROR1,MERTK,DDR1,FLT3,EGFR,NRP2 |
| 6.596e-03 | -5.02 | JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN | MSigDB lists | JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN | 43 | 13 | 17758 | 2588 |
GNAS,TEF,NDRG1,HDAC11,CST3,CLSTN1,NDRG2,FTH1,ATP1B1,CTSD,SEPP1,CAMK2G,ACOT7 |
| 6.598e-03 | -5.02 | thalamus | COSMIC cancer mutations | thalamus | 296 | 59 | 17775 | 2585 |
CCNE2,PARP12,CDK17,ACVR1,RET,ETV5,XYLT1,ARFGEF1,TP53,NES,TDRKH,PHLDA1,FAM101B,PPP2R3A,RB1,MDM1,CTNNB1,CTSC,PTEN,MSH2,DLG1,SMO,PIK3CA,GLB1L2,ECE1,TIAM1,SNED1,MSH6,TUBA4A,ABCC1,MYO5B,BAG4,AKT1,TBC1D8B,DEPDC4,PIK3R1,PDE5A,KCTD20,AKAP3,PYGO1,IDH1,GNA11,EGFR,AHRR,GNAS,HS6ST1,NCOA3,PLEKHG6,JAK1,FGFR2,CSTF2,FZD5,SHROOM2,HOOK1,ABCA1,COBL,RPS6KA3,MELK,PCSK5 |
| 6.648e-03 | -5.01 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN | 186 | 40 | 17758 | 2588 |
NFKBIE,TAB3,TSC22D3,MAN1A2,MESDC2,SGPL1,CDK14,RB1,ADD3,RNF128,CYR61,LMO4,PCYOX1,PRKCI,FXYD5,CCDC82,STT3B,ACAD8,FAM134C,SUN2,ATL1,ADCK3,FOXJ2,RC3H2,PLEKHO1,KIF1C,CALCRL,PTGFRN,LRRC42,ARHGAP24,SCARB2,JAK1,FAM3C,TMC5,PRPS2,SH3BGRL2,RELL1,MAP3K5,ARF6,WBSCR27 |
| 6.648e-03 | -5.01 | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_UP | 186 | 40 | 17758 | 2588 |
COL9A3,ST13,REPS2,ADO,XYLT1,SMARCAL1,NKRF,RASGRP3,PARM1,CDK14,TNS3,IRAK1,KCNN4,TMEM62,BHLHE41,OPN3,UBE2J1,SCN2A,CLIP2,EPHX1,SEMA3B,PIGC,SYPL1,SOD1,ING1,EAF2,PCTP,CD83,SERTAD2,FA2H,ITPR1,RAB31,SH3BP4,CLMN,IRF7,LRRK1,CHPT1,LTA4H,DLAT,MAPK12 |
| 6.648e-03 | -5.01 | GSE27786_LSK_VS_NKCELL_DN | MSigDB lists | GSE27786_LSK_VS_NKCELL_DN | 186 | 40 | 17758 | 2588 |
DDX58,HECA,SORT1,CPEB4,DHPS,DNAJC3,HEXB,TRAPPC8,CDIPT,PGAP1,VPS26A,RINL,KLF3,RRBP1,AIM1,AKR1B1,CCDC82,ABCD1,TNFRSF18,FAR1,FAM134C,GCNT1,SUN2,TRIM8,CITED4,NRBF2,EGFR,FZD7,RBM47,TRIM69,AXL,NFKBIA,NLRC5,AGFG2,CHMP4B,RELL1,OSR1,ARF6,ESYT2,CTDSP1 |
| 6.648e-03 | -5.01 | GSE27786_BCELL_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_BCELL_VS_CD4_TCELL_UP | 186 | 40 | 17758 | 2588 |
PLEKHG3,GALK1,IL15,OAT,HMGXB4,SAC3D1,ATP6V0B,TNS3,MGAT1,GALNS,CST3,AK3,CDKN2D,DDX59,KCTD3,MYO5A,CKAP4,SYPL1,HES1,RHOA,WNT10B,STAU2,LPGAT1,AURKB,NPHP3,ITPR3,NUBP1,IDH1,DCP2,BCL10,CNOT2,NIPSNAP3A,YOD1,ICOSLG,CD81,ST3GAL1,TRAF5,LRRC57,JARID2,DLAT |
| 6.656e-03 | -5.01 | LEE_RECENT_THYMIC_EMIGRANT | MSigDB lists | LEE_RECENT_THYMIC_EMIGRANT | 203 | 43 | 17758 | 2588 |
LZTFL1,UBASH3B,RASA2,XIAP,GATA3,VARS2,PM20D2,QSOX2,SYTL2,TOP2A,FUT8,TOX2,DAPK1,USP38,TSPAN13,TAGLN2,PDE4D,BTBD3,SPRY2,SMC4,CKS2,ACBD5,PCGF5,TIMP2,B3GNT2,PLSCR1,OXR1,PTGER4,VEZT,CBL,STK17B,SOCS3,ANKRD10,CACHD1,NIPSNAP3A,OTUD6B,CDCA7L,FAM3C,NR4A2,NFKBIZ,CMPK2,TOB1,ZNF720 |
| 6.715e-03 | -5.00 | pigment granule | cellular component | GO:0048770 | 103 | 25 | 17570 | 2579 |
LAMP1,SYPL1,HSP90B1,CD63,CTSB,FLOT1,PDIA3,GGH,RAB38,ERP29,SYTL2,PDIA4,ATP1A1,CTNS,P4HB,CAPG,AHCY,RAB29,ATP1B3,CTSD,RAB27B,MYRIP,PDIA6,ANXA11,MYO5A |
| 6.715e-03 | -5.00 | melanosome | cellular component | GO:0042470 | 103 | 25 | 17570 | 2579 |
LAMP1,SYPL1,HSP90B1,CD63,CTSB,FLOT1,PDIA3,GGH,RAB38,ERP29,SYTL2,PDIA4,ATP1A1,CTNS,P4HB,CAPG,AHCY,RAB29,ATP1B3,CTSD,RAB27B,MYRIP,PDIA6,ANXA11,MYO5A |
| 6.768e-03 | -5.00 | viral entry into host cell | biological process | GO:0046718 | 86 | 22 | 16441 | 2455 |
LAMP1,PVRL4,CD55,ITCH,CTSB,CR2,F11R,DAG1,ICAM1,XPR1,WWP2,CD46,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1,CD81 |
| 6.768e-03 | -5.00 | bone morphogenesis | biological process | GO:0060349 | 86 | 22 | 16441 | 2455 |
CYP26B1,INPPL1,RUNX2,HSPG2,SOX9,RAB23,PHOSPHO1,OSR2,DHRS3,GNAS,COL13A1,FGFR2,IMPAD1,MEGF8,NAB2,FGF18,TFAP2A,CSGALNACT1,TWIST1,SHOX2,RARG,SP5 |
| 6.781e-03 | -4.99 | LEE_AGING_NEOCORTEX_UP | MSigDB lists | LEE_AGING_NEOCORTEX_UP | 88 | 22 | 17758 | 2588 |
MYL9,HSP90B1,PPP1R2,NR4A1,NDRG1,NUB1,SAT1,CYB561,CTSZ,CD40,FOS,LGALS3BP,M6PR,SPP1,CTNNB1,ADRBK1,LIMK1,DLG1,CD9,ATP1B3,AK3,CTSD |
| 6.781e-03 | -4.99 | MODULE_426 | MSigDB lists | MODULE_426 | 88 | 22 | 17758 | 2588 |
CYP26B1,ARAP2,SYBU,FTH1,MAPK4,LACTB2,NUCB2,PPP1R14C,TCN2,ELF3,CNTNAP1,PHYHIP,SRPX,COL13A1,ACVRL1,AGBL5,TFAP2A,MAL2,TSPAN1,SHROOM2,IGSF3,EPHX1 |
| 6.800e-03 | -4.99 | intracellular organelle lumen | cellular component | GO:0070013 | 4116 | 654 | 17570 | 2579 |
TRIM24,ADD1,IBTK,AASS,MRPS15,DNAJC3,HEXB,XIAP,SMARCAL1,CCNO,DHX8,TGOLN2,MORF4L2,SYTL4,DPP8,BARD1,PHF1,TP73,NPM2,CALM2,DAPK2,WEE1,PSMD1,RGS12,MUC4,UBE2T,TUBG1,PPP1CA,ACOX2,WBP4,ERAP2,SMARCA2,TNIP1,SPRTN,MTRF1L,TFAP2C,LOXL2,GINS4,COL12A1,LIMK1,HDAC1,MRPS28,RNASEL,PDPR,ANXA11,NXT2,ALDH6A1,GGA1,NUAK1,SOX9,FAM21C,LMNA,GNS,FLII,DNPEP,ZCCHC17,ATP5H,NEK2,FBXL14,CADPS2,USP1,MYDGF,MAPK7,C9orf72,MCCC2,REC8,UFD1L,KIF20A,MAPKAPK3,SALL4,STAT4,PYM1,ERO1A,FHL2,MYBL2,KIF20B,SRSF5,ELK1,ILK,TP53INP2,PSMA4,DCP2,SCARB2,NCOA3,ETS2,HTT,SETD3,ITPR1,AURKA,GDF11,CFAP20,CBX5,RPS6KA3,GRHL2,ACTR8,ETNK1,PKP2,TESK2,MAPK4,PRKACA,CCND1,RCN1,MUC16,SP100,DACT1,ARL4D,CDKN2D,MYT1,ETV4,RNF169,COL6A2,NRBF2,AGPS,SYNE2,HTATIP2,CDCA2,NUSAP1,RAB38,GTF2A2,PEX5,CCNB3,WWTR1,PDXK,RGS14,GEN1,ARNT,MAPK12,TAOK2,HSP90B1,GCAT,BACE1,ESRP1,DCAF7,SDC4,HABP4,PDIA3,GMCL1,CTSZ,PKN1,TMA16,ETS1,NFAT5,PDIA4,NEO1,CTNNBIP1,DTX3L,ZFX,ADD3,CTSC,ARSG,ANKS1B,GPC3,FAM20B,FDXR,ECI2,MAPK11,AK3,RAG1,TMX1,MED22,CRTAP,PARP9,ACBD5,PLSCR1,BCL9,UBE2A,AK4,RAB11FIP2,ATXN7L3,NR1D2,NR4A3,HMGA1,CMPK2,NUP37,USF2,SRSF9,FOXA1,ACOT7,PHC1,AGRN,EPAS1,CUL4B,SUDS3,ARFGEF1,MCCC1,NDC80,LMCD1,NDRG2,DNAJB11,NENF,HDAC6,PDGFB,SDC1,FANCI,PCNA,RPS6KA2,CTNNB1,P4HB,PSMC2,SLC44A1,DUSP10,SMAGP,PLK1,THRB,PCGF5,ING1,STAU2,CBX6,C12orf65,EZR,ERP44,KLK6,EAF2,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,OPTN,KDM4D,MSL1,KLF12,MAP2,P4HA2,ZNF367,KPNA2,MAFF,PRKAA2,RUNX2,HJURP,PSMD7,ASAH1,RACGAP1,RB1,DAZAP1,GATA2,PAK2,MDFIC,FAR2,WNT3A,PSMA5,MRPS33,SPATA13,SCRIB,TCF7,PDK3,G2E3,SMN1,CDK5R1,MAPKAPK2,EPN3,H1F0,COL13A1,P4HA3,ZDHHC7,AKIP1,CCNB2,CTBP1,USP43,RAD21,NF2,HOXB7,UPF3B,FOXM1,P3H2,TP53,RHPN2,CCNL1,BAHD1,PCBP1,SDF4,PER2,TTC21B,PDGFA,KMT5C,TACC2,PLK4,NOTCH3,OAS3,MINPP1,EGLN3,FAR1,CTDSP2,GM2A,SIRT1,PPIF,ERLEC1,TCEB2,AKT1,FIGNL1,CDC20,SERTAD3,DAG1,ATP13A2,DNAJC10,PTGS2,IDE,RBL1,PSMD3,STK38,XRCC3,IRF7,LTA4H,CTDSP1,GSDMD,COL9A3,CMAS,PACSIN2,GOLIM4,CD63,TAB3,CTSB,BLVRB,MCTP2,SWI5,CDCA8,ERI2,ERCC6L,PSMD10,GTF3A,NKRF,HMGN3,CRABP2,AIP,DNAJB9,H1FX,GTF2F2,TFAP2A,FAM63A,SGK1,BUB1,ALDH7A1,HMGCL,KLF9,HEXIM2,CAMK2G,HES1,PSMB4,HMGN5,NR3C1,GUSB,PLAUR,LITAF,PPARA,MAML2,COL7A1,BCAR1,DDX23,FUCA1,SERPINA1,NEIL3,CDCA7L,NMI,FGF18,E2F1,PGRMC1,SH3BGRL2,ACADM,UBE2C,HIPK3,ZBTB33,DIS3L,GAA,PNISR,TXN,HSPG2,SSH1,FAM129B,GATA3,CUL1,PSME1,CCNB1,OAT,SEPT4,CENPN,HELZ2,RGS3,POLL,IRF2,ZBTB18,LAMP2,LOC81691,CDYL,PIF1,AURKB,SLC25A5,PRIM1,PPP2R4,FAM110C,DLAT,RECQL,DGKQ,KIF23,AKAP17A,NOTCH2,PSIP1,BMP2K,MECOM,SH3RF2,CALR,SNX18,BDH1,MSH2,CTSD,EEF1D,GID8,PRODH,DDB2,PMPCB,CALM1,WHSC1,VEZT,KDM3A,JADE2,NFIB,PRKAG2,FAM64A,WDR19,APPL2,PIAS2,SFMBT1,CABIN1,NR4A2,ZBTB34,NRBP1,IRF1,ELK4,SPRED1,CEP70,TRIP10,THRA,RPS6KA1,CCDC110,SUZ12,CERCAM,BCL2L1,FLT3,CYHR1,CCNA2,TNPO2,CDKN1B,RNASEH2A,LGMN,MED30,NR2C1,ATG4D,CDKN2AIP,TMEM43,FOXJ2,LYRM1,UTRN,TEP1,PKMYT1,PYGO1,RAD17,ITPR3,H2AFV,ATP10D,SP4,NIN,CEP162,ZNF641,CFAP45,ACAD10,STAT1,PPP1CB,KLF5,NR3C2,CBX7,MRPS9,DEPDC1,CENPI,CBLL1,SPR,TEAD3,AKIRIN1,OXCT1,PHF7,PTEN,PPP1R10,PRC1,ERCC2,MAP3K7,CITED2,CNPY3,GFI1,MSH6,NCOA2,SMC4,PDGFC,TGIF1,PCCB,CASK,ALDH2,PAPD7,FURIN,DIAPH2,FOS,ARSK,CPTP,CRTC2,ACADSB,PRDX3,FGFR2,CSTF2,ERAP1,NCAPG2,ARSB,JARID2,CCNC,CASP3,CRYM,CPT2,UBE2Z,MPP5,TAF6L,ERP29,ECI1,TRIM68,TSEN34,CHPF,GRHL1,ZCCHC12,CDKL5,SIVA1,PHTF1,CAPG,AKR1B1,ANKRD12,ASH2L,NFU1,STK35,SOD1,CENPA,TRIM8,CXXC5,ASXL1,LAP3,MRPS18A,MRPS36,TCN2,NEIL1,GPRC5B,HPSE,TDRD7,TRIM45,IARS2,GLA,PPP2R5D,PSMC1,NR2C2,PCSK5,PPP1R12A,ETV5,CALM3,PM20D2,ADAMTSL4,DUSP5,CES2,COL6A1,SRP54,ZRANB1,ACAD8,LRIF1,ETV7,ELK3,OXR1,HMG20B,PDIK1L,SOX13,FECH,NUDT16,UAP1,UTP14C,CDCA5,PAPD5,CTSA,RARG,COL16A1,CCNE2,SORBS1,PAX6,IL15,PSME2,HDAC11,PDIA5,SOD2,COL18A1,MORC4,PHLDA1,SAP130,LRRC45,SETDB2,ETHE1,NFKB2,PDIA6,HSPA2,UPF3A,TAF5,MRPS35,ERBB2IP,SNAPC2,DUSP4,FANCE,CDC25C,PDHX,JADE1,HSF4,ALDH5A1,STAT6,PEX2,TLE1,SGOL1,CBX4,KDELC2,GLIS3,SH3D19,COL4A5,INTS8,HDAC9,IRF2BPL,TOP2A,CARD8,TAF1B,LLGL2,GALNS,TOX2,CKS1B,H2AFY,SUN2,CENPC,NR4A1,SYBU,RC3H2,OGDHL,RUNX3,POLD3,MPV17L2,SPAG1,CTSL,CASP7,TRIM69,HNRNPH2,DHRS2,CTSV,UBE2D2,TADA2B,ARRB1,GLB1,HOXB13,ZMIZ1,AHR,ABCG1 |
| 6.802e-03 | -4.99 | eye-uveal_tract-malignant_melanoma | COSMIC cancer mutations | eye-uveal_tract-malignant_melanoma | 153 | 34 | 17775 | 2585 |
RECQL,NF2,REPS2,RET,CUL4B,FHDC1,TP53,ERBB2,SNX9,FLT3,LRRC45,RB1,SNX13,CTNNB1,CDH1,PTEN,MSH2,SMO,PCYOX1,PIK3CA,EEF1D,MSH6,SNX7,AKT1,LAP3,PIK3R1,FAM73B,IDH1,SESN1,GNA11,EGFR,GNAS,FGFR2,JAK3 |
| 6.809e-03 | -4.99 | ATACCTC,MIR-202 | MSigDB lists | ATACCTC,MIR-202 | 175 | 38 | 17758 | 2588 |
FARP1,GRHL2,CPEB4,DNAJB11,FAM101B,PGAP1,DNAJB9,CCND1,RB1,CALD1,FAR2,MYRIP,GAD1,SCYL3,CRTAP,DUSP1,MOB4,LAMP2,TAF5,MMD,CAPN6,KIAA0040,ZC3H11A,LPGAT1,RNF165,ZKSCAN2,KBTBD8,CBL,DPYSL3,SERTAD2,SLC25A4,RAB11FIP2,CSNK1G1,PCDH19,STARD13,CPEB2,NDST3,STARD3NL |
| 6.809e-03 | -4.99 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | 175 | 38 | 17758 | 2588 |
GRN,COL9A3,RASGRP3,C11orf95,CDK14,TNS3,IRAK1,METTL7A,CD22,BHLHE41,PLCG2,OPN3,TSPAN13,ITM2C,SYK,GM2A,SCN3A,FARP2,ORAI2,SLC37A1,EAF2,CD40,ALCAM,ADRBK2,ATP10D,NCOA3,BANK1,SWAP70,PRCP,CORO1C,FAM3C,SLC2A6,DTX4,RAB31,TLE1,DHTKD1,CLMN,LRRK1 |
| 6.818e-03 | -4.99 | integral component of organelle membrane | cellular component | GO:0031301 | 259 | 53 | 17570 | 2579 |
SUN1,CCDC109B,PINK1,ARMCX3,LFNG,HLA-E,HLA-F,APOO,TAP1,P2RX7,SLC8B1,QSOX2,LBR,BCAP31,HLA-A,SGPL1,B4GALNT1,CALR,PQLC2,ENTPD4,STIM1,A4GALT,RRBP1,STEAP2,ABCD1,HLA-C,TECR,P2RX4,SYPL1,SUN2,QSOX1,TMEM43,AMFR,EMC2,SYP,ESYT1,LEMD2,HLA-B,TAPBP,DOLPP1,WFS1,PEX2,CSGALNACT1,DGAT2,TRABD2A,SARAF,PKD2,SAMD8,MCUR1,B4GAT1,ST3GAL1,DMPK,FAM134B |
| 6.821e-03 | -4.99 | DLG1 (discs, large homolog 1 (Drosophila)) | protein interactions | 1739 | 86 | 23 | 16036 | 2547 |
DLGAP1,KCNJ12,SCN5A,ADAM17,CASK,PAX6,GRIK2,FZD4,PBK,EZR,CALM3,LRRC1,APBA1,TANC1,FZD7,PTEN,KIF13B,DLG1,MPP2,MARCH2,DLG3,WNT3A,MAPK12 |
| 6.826e-03 | -4.99 | benign_melanocytic_nevus | COSMIC cancer mutations | benign_melanocytic_nevus | 34 | 11 | 17775 | 2585 |
KIF5B,CTNNB1,AKT1,CEP89,PIK3CA,TP53,GNA11,EGFR,HLA-A,MYO5A,LMNA |
| 6.826e-03 | -4.99 | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I | 34 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,SMO,PIK3CA,IDH1,GNA11,EGFR |
| 6.830e-03 | -4.99 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_IV | 48 | 14 | 17775 | 2585 |
SCN5A,FAT4,PTEN,ICAM5,FDXR,MSH2,TP53,CDKN1B,ESYT1,IDH1,SYK,EGFR,DCBLD1,MSH6 |
| 6.834e-03 | -4.99 | TRIF-dependent toll-like receptor signaling pathway | biological process | GO:0035666 | 81 | 21 | 16441 | 2455 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,NFKBIA,UBE2D2,NOD2,MAPK11,IRF7,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 6.834e-03 | -4.99 | multicellular organismal catabolic process | biological process | GO:0044243 | 81 | 21 | 16441 | 2455 |
COL9A3,ADAMTS2,MRC2,ADAM17,COL6A2,CTSB,FURIN,P2RX7,COL18A1,KLK6,COL7A1,COL4A5,COL12A1,MMP15,CTSL,COL13A1,COL6A1,ADAM15,ADAMTS14,CTSD,COL16A1 |
| 6.847e-03 | -4.98 | erythrocyte differentiation | biological process | GO:0030218 | 71 | 19 | 16441 | 2455 |
CASP3,KLF2,DYRK3,ADD1,EPAS1,DMTN,THRA,NFE2L1,GATA3,SLC11A2,SFXN1,FECH,RB1,TGFBR3,BCL6,PTBP3,ERCC2,SLC25A38,JAK3 |
| 6.847e-03 | -4.98 | epithelial cell migration | biological process | GO:0010631 | 71 | 19 | 16441 | 2455 |
NR4A1,TGFBR1,LOXL2,EGR3,PKN1,ANLN,EMP2,S100A2,CORO1B,GPLD1,NOV,PTEN,SCG2,PIK3CA,STAT1,EPHB4,PLXND1,ARSB,CYP1B1 |
| 6.859e-03 | -4.98 | oligodendroglioma | COSMIC cancer mutations | oligodendroglioma | 21 | 8 | 17775 | 2585 |
CDKN2C,NF2,CTNNB1,PTEN,TP53,NOTCH2,IDH1,EGFR |
| 6.863e-03 | -4.98 | toll-like receptor TLR6:TLR2 signaling pathway | biological process | GO:0038124 | 76 | 20 | 16441 | 2455 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 6.863e-03 | -4.98 | toll-like receptor TLR1:TLR2 signaling pathway | biological process | GO:0038123 | 76 | 20 | 16441 | 2455 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 6.865e-03 | -4.98 | Keratan sulfate/keratin metabolism | REACTOME pathways | R-HSA-1638074 | 33 | 11 | 8202 | 1235 |
GNS,B3GNT7,SLC35D2,B3GNT2,HEXB,GLB1,B4GAT1,B4GALT4,B4GALT3,ST3GAL1,CHST2 |
| 6.868e-03 | -4.98 | GSE17721_LPS_VS_PAM3CSK4_0.5H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_0.5H_BMDM_UP | 192 | 41 | 17758 | 2588 |
LMO7,SORBS1,CHCHD7,MRPS15,RALBP1,LRP4,MMADHC,PSMD7,PBX3,GTF3A,PLA2G16,NUCB2,TSEN34,ELMO2,CYP2S1,RPL39,N4BP3,DUSP10,IL17RA,OSTF1,APIP,RAG1,TTPA,SCN3A,HES1,CENPA,B9D2,PRRC1,PNKD,STEAP1,ZMPSTE24,NUDT16,ALDH3B1,CCDC6,SLC4A3,TDRD7,CANT1,MAPK13,MDH1,ZMIZ1,RPL22 |
| 6.868e-03 | -4.98 | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_UP | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_UP | 192 | 41 | 17758 | 2588 |
ALDH6A1,FAM160B1,ELOVL7,ATP2C2,GNAL,ARL4C,CACNA2D2,SNN,FAM81A,FAM101B,IL18R1,TSPAN17,CYP39A1,ZNF212,RPS6KA2,FRY,POLL,ECE1,ERBB3,PXMP4,ETHE1,PHKG2,S100A6,ATP2B1,EPHX1,P2RX4,SYNE2,PDE5A,EMP3,TANC1,FOS,FOXD2,NAAA,NEIL1,MID1IP1,PVRL2,NR1D2,APPL2,PGM2L1,USF2,CTBP1 |
| 6.868e-03 | -4.98 | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | 192 | 41 | 17758 | 2588 |
GOLIM4,LGALS3,NDRG1,FRMD6,PDIA5,KCTD12,ERP29,DDR1,TNFSF9,SLC35E4,FAM111A,MDM1,HSF2,OXCT1,NPNT,RPL39,FOSB,ERBB3,IQGAP3,SNX10,CPE,LAMP2,PMPCB,HMGN5,GUSB,BNIP3L,FBXO8,FAM73B,SNAPC2,MRPS36,PSMA4,ULK2,VCP,DPYSL3,ONECUT1,H1F0,TIMM8A,OSMR,NR4A2,LIFR,MAPK12 |
| 6.868e-03 | -4.98 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | 192 | 41 | 17758 | 2588 |
ANXA3,DLGAP5,FOXM1,SEC61G,PTTG1,FLOT1,FTH1,PHLDA1,BMP2K,KCTD9,UHRF1BP1L,BTG3,RANBP1,NEK2,CKS1B,AKR1B1,BUB1,KNTC1,ERCC2,MANF,RNASEH2A,GFI1,APOBEC3G,MYO5A,FAH,CKS2,NFE2L3,LAP3,PBK,WHSC1,GGH,PDK3,VCP,WIPI1,PSMD3,AURKA,CCNB2,MAD2L1BP,SERPINB1,ESPL1,ACOT7 |
| 6.868e-03 | -4.98 | GSE17721_CTRL_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_6H_BMDM_UP | 192 | 41 | 17758 | 2588 |
CCNI,GOLIM4,AVPI1,NF2,CUL4B,SMARCAL1,TP53,TESK2,TGFBR1,PRKACA,ELMO2,BDH1,N4BP3,COL6A1,TBCD,TRIM3,TAX1BP3,TSPAN13,ERBB3,PHKG2,CRTAP,GPX4,PIGC,SOD1,ERMP1,PTPN18,MMD,LPGAT1,MGAT4B,CYS1,ARHGDIB,GLO1,ANKRD10,TMEM50B,FASTKD1,SLC25A4,PELI2,STK38,PIAS2,MYL12B,CTDSP1 |
| 6.868e-03 | -4.98 | GSE17721_CTRL_VS_LPS_2H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_2H_BMDM_DN | 192 | 41 | 17758 | 2588 |
UGT8,SLC41A1,BLCAP,DENND2D,APPBP2,BTG3,ARTN,TIMP1,LMO4,GALNS,SNX16,CACNA1D,NFKB2,PTPRE,TSPAN33,MYO5B,PPIF,RAB3B,PLSCR1,NR3C1,CALCRL,CD40,CASP4,EPN3,ENPP1,MMP17,KBTBD2,CSF1,NFKBIA,FGF18,PIAS2,PRKCDBP,FHL1,TTC39C,FZD5,ST3GAL1,IFIH1,PPP2R2D,RARG,CBX4,FGD1 |
| 6.868e-03 | -4.98 | GSE339_CD4POS_VS_CD8POS_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_DN | 192 | 41 | 17758 | 2588 |
TXN,HSP90B1,MRPS15,FRMD6,ITGA6,SERPINB9,PDIA3,MRAS,PDXDC1,SLC35E4,CALR,OXCT1,NPNT,SGK1,RPN2,MANF,SMYD5,ITM2C,TRAM1,NAGA,C9orf72,PMPCB,SOD1,SEC61B,GCLC,PLEKHO1,LITAF,UBAC1,ERP44,B3GALNT2,STX3,CMTM7,DNAJC10,SCARB2,CD8A,TIMP3,DDOST,ACYP1,ITPR1,ARRB1,ATP1B3 |
| 6.868e-03 | -4.98 | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN | 192 | 41 | 17758 | 2588 |
LMO7,CD82,ARL4C,CYB561,TRIB2,SEPT4,CA8,FBLN1,PHLDA1,DENND2D,MXD1,IGF1R,FICD,CAPG,ARVCF,RAB20,CTTN,LGMN,SCARA3,SLC45A3,TLE6,DUSP1,TIMP2,CASK,DSTN,PLEKHO1,CYB5A,TXK,P4HA2,MMP17,STAT1,RYK,FGD6,STK39,SH3BGRL2,HOXB13,ITGAV,GEM,TRAF5,SRSF9,PKIA |
| 6.877e-03 | -4.98 | SCF(Skp2)-mediated degradation of p27/p21 | REACTOME pathways | R-HSA-187577 | 56 | 16 | 8202 | 1235 |
CCNE2,PSMB4,PSME2,PSMD7,CUL1,PSMD10,PSME1,PSMA4,CCNA2,PSMD1,PSMD3,PSMC2,CKS1B,CDKN1B,PSMC1,PSMA5 |
| 6.884e-03 | -4.98 | V$COUP_DR1_Q6 | MSigDB lists | V$COUP_DR1_Q6 | 232 | 48 | 17758 | 2588 |
BCAM,PAX6,ARHGEF7,PNPLA2,HDAC11,TP53,ERBB2,CRABP2,C3orf18,PRKACA,PRR7,FBLN1,SYTL2,CYP26A1,C1orf116,SS18,ZYX,CDK16,LMAN2L,RRBP1,CKS1B,IQCD,SMYD5,NR2C1,TPCN1,ATP2B1,LAMP2,LONRF3,AGPS,ASXL1,NR4A1,SLC11A2,KLK6,F12,CLCN2,BSDC1,PGF,INSR,C19orf66,MAP3K11,NR4A3,OVOL1,MRPS28,EIF4EBP2,ARF6,FOXA1,HOXC13,DIS3L |
| 6.891e-03 | -4.98 | Thyroid hormone signaling pathway | KEGG pathways | hsa04919 | 118 | 29 | 6908 | 1076 |
THRB,AKT1,PFKFB2,THRA,CASP9,PIK3R1,TP53,NOTCH2,ATP1B1,PRKACA,RHEB,CCND1,NCOA3,PLCG1,ATP1A1,CTNNB1,PLCG2,STAT1,PIK3CA,HDAC1,RCAN2,ATP1B3,ITGAV,NOTCH3,PIK3CD,TBC1D4,PLCB2,MED30,NCOA2 |
| 6.910e-03 | -4.97 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | 120 | 28 | 17758 | 2588 |
DOCK4,ANXA3,KLF2,FARP1,ANKRD13D,FRMD4A,GGA1,PYROXD2,ATP8A1,CORO2A,MGAM,SLC11A2,TNS1,TGFBR1,SEPP1,SFXN5,CYP4F3,NRP2,PARM1,SPAG1,CPNE2,PI4K2B,RPS6KA2,BHLHE41,DCUN1D1,TACSTD2,TMEM37,ALPK1 |
| 6.921e-03 | -4.97 | laminin binding | molecular function | GO:0043236 | 29 | 10 | 16491 | 2452 |
BCAM,ITGA3,LGALS3,AGRN,LYPD3,ITGA7,NTN4,TINAGL1,DAG1,LYPD5 |
| 6.926e-03 | -4.97 | Deactivation of the beta-catenin transactivating complex | REACTOME pathways | R-HSA-3769402 | 42 | 13 | 8202 | 1235 |
CTNNBIP1,CTNNB1,AKT1,BCL9,SOX9,XIAP,TLE1,HDAC1,TCF7,ASH2L,PYGO1,CTBP1,SOX13 |
| 6.937e-03 | -4.97 | BALDWIN_PRKCI_TARGETS_UP | MSigDB lists | BALDWIN_PRKCI_TARGETS_UP | 34 | 11 | 17758 | 2588 |
NOV,TSPAN6,PAK2,CBX6,SLC11A2,TGOLN2,MPP5,EIF4EBP2,TRIB2,SEPP1,RHOB |
| 6.937e-03 | -4.97 | BIOCARTA_MPR_PATHWAY | MSigDB lists | BIOCARTA_MPR_PATHWAY | 34 | 11 | 17758 | 2588 |
GNAS,RPS6KA1,PAQR5,PRKAR2B,ARPC2,CCNB1,MYT1,CDC25C,CDK1,PRKAR1A,PAQR7 |
| 6.937e-03 | -4.97 | AIGNER_ZEB1_TARGETS | MSigDB lists | AIGNER_ZEB1_TARGETS | 34 | 11 | 17758 | 2588 |
EPCAM,CDH1,CRB3,TSPAN15,SHROOM3,CDH3,F11R,TACSTD2,MAL2,TSPAN1,OCLN |
| 6.944e-03 | -4.97 | thymic_carcinoma | COSMIC cancer mutations | thymic_carcinoma | 17 | 7 | 17775 | 2585 |
ERBB2,AKT1,PTEN,EGFR,RET,PIK3CA,TP53 |
| 6.944e-03 | -4.97 | liver-other-adenoma | COSMIC cancer mutations | liver-other-adenoma | 17 | 7 | 17775 | 2585 |
GNAS,CTNNB1,JAK1,IL6ST,EGFR,PIK3CA,TP53 |
| 6.944e-03 | -4.97 | thymus-thymoma | COSMIC cancer mutations | thymus-thymoma | 17 | 7 | 17775 | 2585 |
ERBB2,AKT1,PTEN,EGFR,RET,PIK3CA,TP53 |
| 6.944e-03 | -4.97 | thymoma | COSMIC cancer mutations | thymoma | 17 | 7 | 17775 | 2585 |
ERBB2,AKT1,PTEN,EGFR,RET,PIK3CA,TP53 |
| 6.949e-03 | -4.97 | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS | MSigDB lists | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_ALDEHYDE_OR_OXO_GROUP_OF_DONORS | 21 | 8 | 17758 | 2588 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH1A3,AOX1,ALDH7A1,ALDH3A2 |
| 6.949e-03 | -4.97 | REACTOME_ERK_MAPK_TARGETS | MSigDB lists | REACTOME_ERK_MAPK_TARGETS | 21 | 8 | 17758 | 2588 |
RPS6KA2,RPS6KA1,MAPK11,MAPK7,ELK1,DUSP4,PPP2R5D,RPS6KA3 |
| 6.949e-03 | -4.97 | LANDEMAINE_LUNG_METASTASIS | MSigDB lists | LANDEMAINE_LUNG_METASTASIS | 21 | 8 | 17758 | 2588 |
UGT8,ITGB8,PTEN,CALB2,GYLTL1B,CDH3,SPSB1,ODF2L |
| 6.949e-03 | -4.97 | SAGIV_CD24_TARGETS_UP | MSigDB lists | SAGIV_CD24_TARGETS_UP | 21 | 8 | 17758 | 2588 |
TRIM8,SLC4A4,ASPM,CABP1,FRYL,N4BP3,ARFGEF1,SMC4 |
| 6.949e-03 | -4.97 | VERNELL_RETINOBLASTOMA_PATHWAY_DN | MSigDB lists | VERNELL_RETINOBLASTOMA_PATHWAY_DN | 21 | 8 | 17758 | 2588 |
CCND1,DYNLRB1,CTGF,ITGB8,SH3BP4,APPL2,CLIP4,CITED2 |
| 6.949e-03 | -4.97 | WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP | 21 | 8 | 17758 | 2588 |
TOP2A,KIF20A,ASPM,SLC2A6,PRC1,NEK2,BARD1,CDK1 |
| 6.949e-03 | -4.97 | KEGG_GLYCOSAMINOGLYCAN_DEGRADATION | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_DEGRADATION | 21 | 8 | 17758 | 2588 |
GNS,HPSE,GUSB,GALNS,HEXB,GLB1,HS3ST3B1,ARSB |
| 6.949e-03 | -4.97 | MACLACHLAN_BRCA1_TARGETS_UP | MSigDB lists | MACLACHLAN_BRCA1_TARGETS_UP | 21 | 8 | 17758 | 2588 |
TOP2A,PCNA,TIMP2,RHOA,TIMP1,CDK16,LFNG,IGFBP2 |
| 6.949e-03 | -4.97 | IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN | 21 | 8 | 17758 | 2588 |
RHOA,PRCP,CST3,CTSA,ARPC2,CTSD,HLA-A,TMX1 |
| 6.959e-03 | -4.97 | GGGATGC,MIR-324-5P | MSigDB lists | GGGATGC,MIR-324-5P | 48 | 14 | 17758 | 2588 |
ZFX,MLEC,RUNX2,ZNRF2,CDK16,THRA,KLF3,WHSC1,YOD1,SEPT4,UNC45B,STARD13,NFAT5,MED22 |
| 6.959e-03 | -4.97 | GUILLAUMOND_KLF10_TARGETS_UP | MSigDB lists | GUILLAUMOND_KLF10_TARGETS_UP | 48 | 14 | 17758 | 2588 |
LASP1,WDFY1,KIFC2,SERPINE2,CELSR2,ATP8A1,NDRG1,TFAP2C,RGS5,MOXD1,SLC25A30,COL16A1,STEAP1,DAG1 |
| 6.959e-03 | -4.97 | PID_AJDISS_2PATHWAY | MSigDB lists | PID_AJDISS_2PATHWAY | 48 | 14 | 17758 | 2588 |
CASP3,FYN,IGF1R,CTNNB1,CDH1,IQGAP1,RET,DNM2,CBLL1,CTNND1,ARF6,TIAM1,EGFR,ZBTB33 |
| 6.959e-03 | -4.97 | FAELT_B_CLL_WITH_VH3_21_DN | MSigDB lists | FAELT_B_CLL_WITH_VH3_21_DN | 48 | 14 | 17758 | 2588 |
ING1,ACBD3,MICB,LMO4,RAB31,PBX3,CDKN1B,ASAH1,PSMD10,NPC2,IFI6,CTDSP2,CBX7,COX7A2 |
| 6.999e-03 | -4.96 | OAT (ornithine aminotransferase) | protein interactions | 4942 | 40 | 13 | 16036 | 2547 |
PGM1,SOD1,FAF2,SOD2,AKR1B1,EZR,CTSA,GOT1,FBXO6,PDXK,DMWD,OAT,EGFR |
| 6.999e-03 | -4.96 | SOCS6 (suppressor of cytokine signaling 6) | protein interactions | 9306 | 40 | 13 | 16036 | 2547 |
IRS2,INSR,ACVR1,TCEB2,TUBB4B,MADD,PIK3R1,UBE2D2,DCUN1D1,USP1,TGFBR1,SAV1,EGFR |
| 7.019e-03 | -4.96 | V$HMGIY_Q6 | MSigDB lists | V$HMGIY_Q6 | 238 | 49 | 17758 | 2588 |
MRC2,HSPG2,MIER3,NDRG2,MAPK4,TEX2,PRRG4,PPP2R3A,C1orf116,ICAM1,KCTD15,RNF220,TACC2,LMO4,SRR,BCL6,ANKRD12,PDE4D,NCAM1,RNF26,GAD1,SMC4,HCN3,B3GNT7,TAF5,HN1L,VAMP3,TFAP2C,PRICKLE1,CALCRL,CD40,POLD3,PNKD,NFIX,PITX2,ONECUT1,NFKBIA,C1orf21,FAM117A,NXPH4,OSMR,KLF5,NR4A2,DONSON,MDH1,CTNND1,ATP1B3,LEMD1,GEN1 |
| 7.027e-03 | -4.96 | FARMER_BREAST_CANCER_CLUSTER_7 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_7 | 17 | 7 | 17758 | 2588 |
ECI2,CDH1,ALCAM,DHRS2,TMEM41B,BLVRB,RND1 |
| 7.027e-03 | -4.96 | BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | MSigDB lists | BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | 17 | 7 | 17758 | 2588 |
MX1,IRF7,IFIT1,IFIT3,IFI6,STAT1,IRF1 |
| 7.027e-03 | -4.96 | BIOCARTA_IL10_PATHWAY | MSigDB lists | BIOCARTA_IL10_PATHWAY | 17 | 7 | 17758 | 2588 |
BLVRA,JAK1,IL10RB,STAT6,STAT4,BLVRB,STAT1 |
| 7.027e-03 | -4.96 | TOMIDA_METASTASIS_DN | MSigDB lists | TOMIDA_METASTASIS_DN | 17 | 7 | 17758 | 2588 |
ENO2,LGALS3,CDH1,DLX4,NR4A1,SAT1,SYBU |
| 7.027e-03 | -4.96 | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | MSigDB lists | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | 17 | 7 | 17758 | 2588 |
CAB39,PRKAA2,STRADB,TSC1,PRKAG2,PRKAA1,RHEB |
| 7.027e-03 | -4.96 | SISTER_CHROMATID_SEGREGATION | MSigDB lists | SISTER_CHROMATID_SEGREGATION | 17 | 7 | 17758 | 2588 |
NUSAP1,CENPE,ZWINT,ESPL1,CDCA5,SMC4,NDC80 |
| 7.027e-03 | -4.96 | MODULE_346 | MSigDB lists | MODULE_346 | 17 | 7 | 17758 | 2588 |
ASAH1,PLD1,GM2A,PLCG2,HEXB,GPX4,B4GALNT1 |
| 7.027e-03 | -4.96 | GENTILE_UV_RESPONSE_CLUSTER_D1 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D1 | 17 | 7 | 17758 | 2588 |
CASP3,WEE1,GEM,RND3,ITGA6,STX3,DUSP1 |
| 7.053e-03 | -4.95 | - | gene3d domains | 2.60.40.720 | 6 | 4 | 9988 | 1574 |
TP73,RUNX3,RUNX2,TP53 |
| 7.055e-03 | -4.95 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-mycosis_fungoides-Sezary_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-mycosis_fungoides-Sezary_syndrome | 53 | 15 | 17775 | 2585 |
RB1,PLCG1,CTNNB1,JAK1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,PRICKLE1,ERBB2,FLT3,JAK3,EGFR |
| 7.055e-03 | -4.95 | mycosis_fungoides-Sezary_syndrome | COSMIC cancer mutations | mycosis_fungoides-Sezary_syndrome | 53 | 15 | 17775 | 2585 |
RB1,PLCG1,CTNNB1,JAK1,AKT1,FGFR2,PTEN,RET,PIK3CA,TP53,PRICKLE1,ERBB2,FLT3,JAK3,EGFR |
| 7.059e-03 | -4.95 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | 181 | 39 | 17758 | 2588 |
MPZL1,GGA1,SCD5,MCTP2,TGFBR1,TRMT2B,DDR1,PARM1,SLC9A7,HDAC9,CDK14,WEE1,TNS3,CD22,FRAS1,PLCG2,PHTF1,MTMR10,DRAM1,TSPAN13,MOXD1,SYK,GM2A,SOCS5,NEK4,CTNNAL1,CXorf57,KCTD20,CR2,LHFPL2,ADRBK2,MAP1B,GALNT3,BANK1,SLC4A4,UTP14C,PHLPP2,DTX4,SERPINB5 |
| 7.059e-03 | -4.95 | GSE14000_4H_VS_16H_LPS_DC_DN | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_DN | 181 | 39 | 17758 | 2588 |
ANXA3,MRPL44,C5orf30,RAB23,BTN3A1,FLT3,RSAD1,LGALS3BP,KCTD9,EPM2A,EPDR1,TMCC3,SLC25A36,SS18,SETDB2,ZDHHC13,TPST1,C9orf72,FAM134C,FAM69A,PIGC,HN1L,NUB1,BTN3A2,GGH,LRRC1,LHFPL2,MPV17L2,BSDC1,PIAS3,ZMYND19,PHLPP2,AGFG2,CSTF2,KLF5,MRPS28,NUP37,TRAF5,ZC3HC1 |
| 7.059e-03 | -4.95 | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP | 181 | 39 | 17758 | 2588 |
BIN1,AVPI1,GRHL2,GALNT12,ITGA6,MTL5,SELL,KBTBD11,NRP2,TSPAN6,SLC16A6,PRICKLE3,IL6ST,TPST1,NCAM1,TSPAN1,TTPA,ALS2CL,HP1BP3,XKR8,MCTP1,RIPK2,WNT10B,UXT,TFAP2C,EPHA1,DPYSL4,CDC25C,EGFR,PLEKHB1,ULK2,SEC14L2,RASGRP2,SCARB2,ACVRL1,LTBP2,ICOSLG,APBA2,TOB1 |
| 7.076e-03 | -4.95 | GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN | MSigDB lists | GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN | 198 | 42 | 17758 | 2588 |
GAS2L1,ACVR1,ENO2,JRKL,NDRG1,ARL4C,CALM3,GTF3A,CRABP2,KTN1,REPS1,LMNA,CALM2,ADD3,RPS6KA2,PTEN,LMO4,SORL1,ECE1,LGMN,IL10RB,CTDSP2,CRTAP,UPF3A,SYPL1,PGM1,ALDH2,SNTB2,DCHS1,CALM1,SNAPC2,FOS,DCP2,FYN,SERTAD2,PLOD2,SEMA4D,USF2,LTA4H,PPP2R5D,ABCG1,CD33 |
| 7.092e-03 | -4.95 | monosaccharide metabolic process | biological process | GO:0005996 | 227 | 48 | 16441 | 2455 |
MAN2B2,GALK1,GAA,INPPL1,UGT8,ENO2,UGP2,SLC25A13,PRKAA1,WDTC1,CALM3,GALM,PRKACA,EPM2A,PER2,CALM2,FUT2,PFKL,FUT8,PIK3CA,FUT1,AKR1B1,GYS1,GOT1,BRAT1,PHKA2,PHKG2,PGM1,AKT1,PFKFB2,GCLC,CALM1,PYGL,PDK3,PKM,CYB5A,CRTC2,IRS2,MAN2A2,FUCA1,DHDH,ONECUT1,ALDH5A1,PGM2L1,MDH1,GLB1,PPP2R5D,DLAT |
| 7.117e-03 | -4.95 | TGCTTTG,MIR-330 | MSigDB lists | TGCTTTG,MIR-330 | 320 | 63 | 17758 | 2588 |
MTM1,ACVR1,RUNX2,SCOC,NF2,ZCCHC24,DCAF7,XIAP,MIER3,TRAPPC8,NKRF,RAB6A,FAM91A1,TRIB2,BMP2K,GRM5,UBE2Q2,TGFBR3,ADD3,ANKS1B,ZNRF2,LHX6,PRKG1,TRIM3,IFIT1,NCEH1,NPTXR,ARMCX6,TIPARP,ITM2C,NCOA2,ATP2B1,IGSF3,METAP2,TRAK2,TAF5,MLEC,BCL9,ACBD3,FOXJ2,ITCH,SYBU,RNF165,MYEOV,RUNX3,GALNT7,PTGFRN,DAG1,SP4,DCP2,SOX13,DPYSL3,BTG1,RND3,SYT7,PHLPP2,RAP2C,E2F1,NR4A3,YOD1,ZC3H12B,SHOX2,ARHGEF9 |
| 7.127e-03 | -4.94 | cysteine-type endopeptidase activity | molecular function | GO:0004197 | 118 | 28 | 16491 | 2452 |
GCA,CASP3,CAPN12,USP31,CAPN6,USP18,CTSB,CASP9,PDIA3,CAPNS1,CTSZ,CASP4,ATG4A,USP6,CAPN2,CTSL,CASP7,CTSC,CTSV,USP1,USP38,TINAGL1,LGMN,ESPL1,CAPN1,USP16,USP43,ATG4D |
| 7.128e-03 | -4.94 | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | MSigDB lists | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | 78 | 20 | 17758 | 2588 |
MX1,QSOX1,SERPINE2,NUAK1,CTSB,SDC4,ASAH1,FTH1,NPC2,ICAM1,IER3,FUCA1,ITGA3,PDLIM3,COL6A1,TACSTD2,HLA-C,CPE,IFI6,ABCG1 |
| 7.134e-03 | -4.94 | negative regulation of cell-matrix adhesion | biological process | GO:0001953 | 29 | 10 | 16441 | 2455 |
CASK,NF2,ACVRL1,PTEN,DMTN,CORO1C,PIK3R1,BCL6,ADAM15,RASA1 |
| 7.134e-03 | -4.94 | salivary gland morphogenesis | biological process | GO:0007435 | 29 | 10 | 16441 | 2455 |
NKX3-1,TWSG1,FGFR2,BMP7,PLXND1,PLXNA1,SEMA3A,DAG1,NFIB,EGFR |
| 7.146e-03 | -4.94 | V$ER_Q6_02 | MSigDB lists | V$ER_Q6_02 | 244 | 50 | 17758 | 2588 |
PAX6,CAPN12,SLC25A27,ARFGEF1,GABRG2,NDRG2,CRABP2,COX6C,C3orf18,PHF1,CYP39A1,HPCAL4,SIRPA,CYP26A1,CDK14,IRF2BPL,CEP97,ITGB8,FAM20C,CDKL5,SH3BP1,SLC16A6,STEAP2,BCL6,TNFRSF12A,MANF,BTBD3,OSGIN1,CCDC88A,DOCK4,ELK3,TMEM43,FZD4,DCHS1,TFAP2C,TCF7,BCL2L13,LCP1,EPN3,PLEKHG6,FGFR2,MADD,RAP2C,ADAMTS14,NXPH4,FHL1,ST3GAL1,ZBTB33,HOXC13,NR2C2 |
| 7.160e-03 | -4.94 | TTTGTAG,MIR-520D | MSigDB lists | TTTGTAG,MIR-520D | 326 | 64 | 17758 | 2588 |
ADD1,TCTN2,DDIT4L,EGR3,ZNF385B,CCND1,PDE4D,LRP11,TRAM1,BTBD3,TIPARP,SCN3A,SULF2,SIRT1,STK17B,SP4,ANKRD10,RBM47,KLF12,KCNK1,PPP1CB,ARRDC1,ADIPOR1,KLF11,ZBTB6,MAFF,ABCA1,CBX4,CMTM4,SCN5A,CPEB4,TAB3,ETV5,PDCL,CNTNAP2,SLC1A3,PHLPP1,ETS1,ZFX,MDM1,LLGL2,BHLHE41,DAPK1,TPST1,FAM84B,CITED2,NCAM1,PIKFYVE,GAD1,ATP2B1,SOCS5,IGDCC4,KDELR1,HES1,SRSF5,KIF11,DCP2,BSDC1,DHX32,FNTA,SERTAD2,PCDH19,NDFIP1,CPEB2 |
| 7.163e-03 | -4.94 | oesophagus-lower_third-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-adenocarcinoma | 6579 | 1013 | 17775 | 2585 |
DOC2A,ACACB,FAM160B1,IBTK,GRIK2,AASS,TRIM5,SLC25A13,RET,CACNA2D2,DHX8,TRAPPC8,LGI3,BAIAP3,CNTROB,SNX9,CA8,BARD1,LTBP3,GRM5,EPDR1,TP73,DAPK2,NAPG,PSMD1,RGS12,MUC4,PPP1R16A,SLC46A1,ALDH1A3,KLF3,ATP13A3,DNM2,SEMA3G,WBP4,TIAM1,IL10RB,CPE,TIPARP,MGAT5,ODF2L,ERAP2,NEK4,NWD1,SMARCA2,TNIP1,SH3BGRL,CDA,MTRF1L,TMEM151A,PRKAR2B,LOXL2,PPP1R14C,MYOM1,GINS4,COL12A1,SLC44A3,PIAS3,ENPP1,WDR11,C17orf51,DNM1L,ATP7B,CELF5,MYLK,FAM114A1,NOD2,AGFG2,ITPKA,LSM14B,NXT2,SCN5A,NFKBIE,FAM169A,TMTC3,SOX9,SLC36A4,ZNRF3,MERTK,TTYH3,MARCH8,GNS,FLII,RAC2,SH3D21,DNPEP,ZCCHC17,FRY,RIMS3,MEGF8,FLRT3,FBXO7,FAM13B,PCYOX1,CADPS2,USP38,ALPK1,STT3B,PANX2,ZMYM1,NCAM1,MYLIP,DGKG,NUP85,TTLL1,NAGPA,HPS3,SLC37A1,KIF20A,SALL4,STAT4,CALCRL,PLS1,NPHP3,MEST,DPYSL4,PCTP,DCP2,C11orf45,DHX32,PTPRF,IL1R1,CACHD1,NCOA3,ETS2,HTT,TEX30,ITPR1,OSMR,AURKA,DYSF,OSCP1,GDF11,TMEM159,NDE1,ARPC2,SERPINB1,XDH,ADAMTS16,EGLN1,DOCK9,NQO1,ACTR8,RHBDL3,WDTC1,RGS20,TESK2,PKP2,PRSS22,NUF2,FAM91A1,PRKACA,APC2,UHRF1BP1L,RCN1,CCND1,RBM23,MUC16,RNF220,ST5,SP100,DACT1,XYLT2,ENPP5,ACSL4,RASGEF1A,ZNF365,MYT1,RNF169,SCN3A,TMCC2,TMEM200B,ENPP4,SNX8,CAMSAP3,SSH3,COL6A2,ERMP1,C6orf1,RIPK2,AGPS,SEPT6,PLEKHO1,SYNE2,SAT1,CDCA2,SYP,TANC1,GIGYF1,CCNB3,SHROOM3,TTC12,CORO1C,AXL,WWTR1,INPP4B,PLEKHG1,DMWD,RGS14,SLC25A30,ISOC1,FARP1,MZT1,HSP90B1,TNRC6C,TAOK2,FAM189A2,CCM2,OSGIN2,PDIA3,ANO9,PKN1,ZNF219,KCNC4,ETS1,IFT27,PDIA4,CAPN2,DTX3L,ZFX,ANK1,ADD3,IGSF9,SLC27A6,ANKS1B,CTSC,ARSG,FAM160A2,KNDC1,GPC3,CALD1,TUBGCP6,BAX,ADAM15,ECI2,WWP1,RAG1,SGCB,TPCN1,TMX1,MED22,PARP9,PVRL4,ADAMTS2,FMN1,TACC1,RAPGEF2,PIK3R1,EIF5A2,MRS2,CXorf57,PLEKHA7,DBR1,SNTB1,C4orf27,CRISPLD2,ABLIM2,DCAF10,RPL12,PROM1,ATXN7L3,RAB11FIP2,PPM1H,ARFGAP3,ITGAV,NUP37,SHOX2,PHC1,TLL2,TMEM131,BCAM,KIAA1462,TRIM2,GNPDA1,EPHA4,CUL4B,ARFGEF1,NDC80,MCCC1,LMCD1,GALM,ITPR2,PDGFB,SPTB,FANCI,TFAP2E,PLS3,SUSD2,RPS6KA2,NUP210,TM9SF2,CTNNB1,RABEP2,P4HB,MKRN3,IL6ST,LMAN2L,PAPSS1,SLC44A1,ABCA2,ANO4,TLN2,MYBL1,TRAM1,DDX59,NEB,ZNF462,PLK1,THRB,PCGF5,PTPN18,MARK1,CELSR2,STAU2,CBX6,EZR,CR2,CCBL2,CKAP2L,ESYT1,IDH1,SESN1,ZBTB7B,VCP,DPYSL3,OPTN,KDM4D,TRIM9,TNS4,HS6ST1,TRAM2,KLF12,MAP2,P4HA2,ZNF367,ARRDC1,KPNA2,PIK3C2B,MYL12B,TC2N,RRAGD,PRKAA2,RUNX2,USH1C,UBASH3B,FXYD3,RASA2,PDCL,RACGAP1,ADCK5,CNTNAP2,DOCK11,FBLN1,ANO1,SSX2IP,MYO5C,B4GALNT1,CORO1B,RB1,DAZAP1,VASP,IGF1R,SPIN4,FRAS1,KIF13B,ICAM5,FCHO1,SLC30A6,FAR2,NTN1,PLCB2,ABCC1,CHSY3,DPYSL5,PCDH1,PLEKHA6,USP31,BTNL9,ZNF320,MGAT4B,SPATA13,SCRIB,EIF2AK1,ZSCAN12,UNC45B,G2E3,PRX,SMN1,FOXD2,FA2H,PVRL2,COL13A1,KBTBD2,ITGA7,PRPS2,SLC2A6,LTBP2,ZDBF2,PLD1,AKIP1,CDAN1,CCNB2,RNF146,USP43,HOXB7,UGP2,TP53,CCDC68,ERBB2,ZNF28,STIL,SYTL2,CDK14,TTC21B,TACC2,EFR3A,LMO4,PPME1,N4BP3,PLCG2,BCL6,PLK4,GLB1L2,ESPN,NOTCH3,SCN2A,FAR1,CTH,CPD,SIRT1,CLCN3,TMTC1,ERLEC1,AKT1,S100A4,CDC20,PTGER4,ATP13A2,PTGS2,ZNF628,DUOX1,ATP1A1,IDE,PTPRJ,PAFAH1B3,RBL1,ADAMTS14,MAOA,EFNA5,IRF7,RPL22,ST3GAL1,AIFM3,LTA4H,ZNF701,NDST3,ZC3HC1,FAM134B,MAN2B2,ZMAT1,CMAS,COL9A3,DYRK3,PACSIN2,CDH22,TRAPPC10,CTSB,GNE,ERCC6L,GABRG2,GDF15,CHAC2,JAG2,CRABP2,AIP,SLC9A2,PPP2R3A,NRP2,SIRPA,FZD6,SH2D4A,GBX2,FOXP2,ALPP,MAGEE1,GTF2F2,SLC35B4,FAM63A,IL17RA,BUB1,SYK,SLC45A3,ATP2B1,GCNT1,FAH,LRRC24,IGDCC4,HMMR,DLGAP1,FBLN5,RHOA,IFITM3,GUSB,NR3C1,AMFR,PRICKLE1,DPP9,COL7A1,AKAP3,NPDC1,PRDX4,USP6,DDX23,CNOT2,FAT4,SCG2,ZNF214,NMI,TMC5,E2F1,FAM117A,PKD2,ICOSLG,TBC1D4,ARHGEF9,ZBTB33,GOLGB1,FAM171B,LAMP1,SUN1,PPP4R4,PNISR,LGR4,HSPG2,SSH1,ATP8A1,FAM129B,KLC2,SEPT4,OAT,PJA2,SLC20A1,ELMOD2,NCS1,CHST2,SESN3,CTGF,RGS3,OSBPL3,PRICKLE3,FOSB,SERINC2,AOX1,PIK3CA,KCNS3,POLL,ATRNL1,SNX16,HYLS1,PACSIN1,XKR8,ORAI2,TMEM68,CDYL,HSPA12A,TNS1,LDB2,POR,RAB2B,ULK2,AHRR,SFXN1,KDSR,PLK2,GNPTAB,SH2D3C,NKD1,BMP1,DHTKD1,NFKBIZ,SERPINI1,WBSCR27,TRAF5,LZTS1,DLAT,DDX58,SEMA6B,MRC2,INPPL1,FRMD4A,TBC1D1,DGKQ,KIF23,TXNDC9,ISYNA1,NOTCH2,APBA1,PRRG4,SH3RF2,MESDC2,DOPEY2,RALGPS2,ITGA3,BHLHE41,SLC16A6,AIM1,RUNDC3B,DAPK1,SORL1,OSTF1,CACNA1D,CTSD,ZNF117,RIMS2,TSPAN33,FAM69A,IGSF3,EPB41L5,GFPT1,SPATA20,GCC2,B3GNT7,KCNJ12,MFI2,KIAA1841,PRSS23,CEP89,TBC1D8B,ANO6,WHSC1,ANTXR1,GLT8D2,RASA1,PDE11A,MMP15,DGKH,GABRD,SLCO4A1,PRKAG2,PLEKHH2,TJP3,ISM1,PIAS2,MPP2,ARAP1,AGBL5,PCDH19,CABIN1,SAMD8,ZBTB34,EFNA1,PER3,IFIH1,NRBP1,PKD1L2,SPRED1,KIF3C,SLC2A4,CAPN12,DLGAP5,TRIP10,S100A11,ST14,NLRX1,BROX,NDRG1,IQGAP1,CAST,THRA,ATP2C2,IRX4,CD274,FLT3,MNS1,ZFYVE9,CD46,APLP2,ACAP2,FAM46A,TRANK1,CNNM4,TNPO2,DAB2IP,EPHB4,PDE4D,OSBPL7,NR2C1,NAGA,DOCK4,CDKN2AIP,SLC5A11,COG2,TMEM43,CAPN6,UTRN,TEP1,KIF1C,PRKCQ,PKMYT1,PYGO1,BCL7B,CBL,ITPR3,ALCAM,ATP10D,ZMPSTE24,NIN,FYN,ZNF641,DDOST,PPP2R5A,POPDC3,JAK1,TSPAN18,KIAA1804,STAT1,PPP1CB,NRG1,MLKL,ZC3H12B,SLC27A3,NR3C2,COBL,DENND5B,WASF3,ARHGEF3,ANKRD13D,DEPDC1,SLC16A14,HAPLN3,SLC41A1,CENPI,EPS8,CBLL1,HERC5,PBX3,NES,PLD2,SEPP1,DNAH3,PNPLA5,SIX4,LGALS3BP,CKAP5,E2F7,FAM111A,OXCT1,RNF128,PHF7,PTEN,CENPJ,FUT8,FJX1,SGK3,PRC1,ATP8B1,ERBB3,MAP3K7,GFI1,SLC16A5,NCOA2,MSH6,OSGIN1,SMC4,FARP2,RASGRF1,TGIF1,ARHGEF28,LONRF3,PAPD7,MPP1,PARP4,ZKSCAN2,FBXO9,DIAPH2,GRTP1,AIF1L,FOS,ARSK,KIF11,GPLD1,CDK5RAP1,RGS9,MAMDC4,DGCR2,PRDX3,RIN3,ABCB1,PGM2L1,WDR91,WDR62,NCAPG2,CPEB2,ESPL1,JARID2,RGMA,EXPH5,LTBP1,CASP3,UGT8,TMEM184B,CAMKK1,UBE2Q1,PLAC1,MPP5,TAF6L,KREMEN1,TMC1,CHPF,ARHGEF10L,ZFYVE16,SIPA1L2,LRRC6,GRHL1,CASC4,ARHGEF37,DPYSL2,ANKFN1,CEP78,DLG1,CAPG,POF1B,ANKRD12,TRPC1,ASH2L,SUN3,TECR,SLC39A10,MYRIP,BTBD3,IL1RAP,CYP1B1,TDP1,SYNE3,ASXL1,ITCH,ROR1,MAN2A2,ZNF114,UEVLD,MADD,IARS2,TRIM45,ZNF165,SP6,RBM43,APBA2,RAP1GAP,MIIP,CPPED1,PCSK5,GRN,PEX6,BVES,ETV5,ASL,ABCG2,PM20D2,FAM81A,PHLPP1,ZNF432,CA2,CES2,OCRL,COL6A1,PRKCI,LIMCH1,KNTC1,C10orf54,RFX5,ETV7,CCDC88A,SNED1,SNX7,KDELR1,PODXL2,PARD3B,OXR1,VWA1,BTN3A2,KIAA1109,HEATR5A,AMDHD1,RANBP9,EGFR,XKRX,TSC1,ONECUT1,INSR,UAP1,TMEM30A,ALPK3,RHOBTB2,SHROOM2,JAK3,COL16A1,AFAP1,DRD1,PROM2,KLF7,CCNE2,NCKAP5,SLC25A24,PAX6,ZSWIM5,SORBS1,FAM92A1,SLC2A8,ABCG4,PDIA5,COL18A1,IL27RA,TDRKH,MRAS,MICALL2,EXT2,ARHGEF16,MXD1,KCTD9,SS18,KCTD15,ZNF687,KIF14,FRYL,SMO,TWIST1,ZBTB49,APIP,ECE1,ETHE1,HSPA2,SOAT1,ZNF525,KREMEN2,PTPRU,ERBB2IP,TMTC2,SNAPC2,CDC25C,DOCK5,CASP4,HSF4,ALDH5A1,STAT6,BHLHB9,OVOL1,TLE1,RCAN2,SPTBN5,PLXND1,AKNA,SGOL1,MAD2L1BP,ABCA1,PPP2R2D,GCLM,SORT1,ARHGEF11,ARHGEF7,SH3D19,TGFBR1,COL4A5,NOTUM,INTS8,TRIB2,POMGNT1,SBF1,RBP7,XPR1,HMGXB4,ITGA2B,HDAC9,IRF2BPL,ADORA1,TAF1B,MLPH,LLGL2,A4GALT,BMP7,TOX2,KIAA0319,TRIM3,IQGAP3,FAM219A,CLIP2,SLC35A1,MYO5A,PHF20L1,NR4A1,ASPM,RC3H2,MBNL3,RUNX3,POLD3,SPAG1,LEMD2,KLHL2,CD8A,CASP7,TRIM69,DHRS2,UACA,GRAMD1C,ZMIZ1,GEM,SOX8,ATP6V1C1,AHR,ABCG1,SNPH,NGEF,ZNF596,CD33 |
| 7.186e-03 | -4.94 | Rac guanyl-nucleotide exchange factor activity | molecular function | GO:0030676 | 13 | 6 | 16491 | 2452 |
FARP1,TIAM1,EPS8L2,FARP2,ARHGEF4,SPATA13 |
| 7.186e-03 | -4.94 | peptidyl-proline dioxygenase activity | molecular function | GO:0031543 | 13 | 6 | 16491 | 2452 |
EGLN3,P4HB,P3H2,P4HA2,P4HA3,EGLN1 |
| 7.194e-03 | -4.93 | BURTON_ADIPOGENESIS_11 | MSigDB lists | BURTON_ADIPOGENESIS_11 | 53 | 15 | 17758 | 2588 |
KIF5B,LMO7,SMARCA2,NR3C1,ARFGEF1,PKD2,SHOX2,ALCAM,SLC12A2,AHR,RASA1,CCDC88A,IRF1,NFIX,SLC25A36 |
| 7.194e-03 | -4.93 | WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER | MSigDB lists | WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER | 53 | 15 | 17758 | 2588 |
TGFBR3,USH1C,PROM1,CES2,SLC4A4,NR4A1,ZCCHC24,LRIG1,MITF,NR4A3,ERBB3,LOXL1,SEPP1,CPE,COBL |
| 7.194e-03 | -4.93 | VANTVEER_BREAST_CANCER_METASTASIS_UP | MSigDB lists | VANTVEER_BREAST_CANCER_METASTASIS_UP | 53 | 15 | 17758 | 2588 |
RTN4RL1,ALDH6A1,LYPD6,FUT8,FGF18,EBF4,ECI2,RAB27B,MYLIP,MYRIP,CHPT1,ZNF385B,SEC14L2,PDIA4,NEO1 |
| 7.194e-03 | -4.93 | WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN | MSigDB lists | WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN | 53 | 15 | 17758 | 2588 |
PODXL2,PROM1,FAM46A,CTGF,CYR61,FZD4,NR4A1,CXorf57,TRIM45,CLDN4,LTBP2,ETAA1,DUSP5,CPPED1,DUSP1 |
| 7.198e-03 | -4.93 | WONG_EMBRYONIC_STEM_CELL_CORE | MSigDB lists | WONG_EMBRYONIC_STEM_CELL_CORE | 332 | 65 | 17758 | 2588 |
CCNC,DLGAP5,GNPDA1,NDC80,TP53,ERP29,CCND1,SS18,WEE1,PCNA,CCNA2,PLK4,KIF22,CKS2,PLK1,CDC20,NUSAP1,GLO1,AURKB,CCNF,MRPS36,SLC25A5,CDK1,PRIM1,MID1IP1,HDAC1,KPNA2,MAPK13,MRPS28,RPL22,DLAT,CDKN1C,CKAP2,ERCC6L,CDCA8,CDCA3,KIF23,RACGAP1,CRABP2,PDIA4,TOP2A,CTSC,BAX,MSH2,NEK2,CKS1B,ALDH7A1,BUB1,ACAD8,PSMA5,SMC4,AMOTL2,TGIF1,HMGN5,KIF20A,MYBL2,AK4,KIF11,PROM1,TIMM8A,CDCA5,AURKA,CCNB2,CSRP2,PHC1 |
| 7.222e-03 | -4.93 | GSE6269_STREP_AUREUS_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_STREP_AUREUS_VS_STREP_PNEUMO_INF_PBMC_DN | 170 | 37 | 17758 | 2588 |
COL9A3,FAM189A2,CD82,PDCL,COL18A1,RAC2,ADD3,CES2,RALGPS2,GNB5,CD22,BDH1,PRKG1,DLG3,IL1RAP,HN1L,TBC1D8B,STAU2,CRIP2,COX11,CR2,KIAA1109,TAPBP,BANK1,FGFR2,ACVRL1,CSF1,IARS2,HDAC1,GDF11,FHL1,TTC9,ANXA9,RPL22,PPP2R5D,HIPK3,RUSC1 |
| 7.230e-03 | -4.93 | CNTFR (ciliary neurotrophic factor receptor) | protein interactions | 1271 | 9 | 5 | 16036 | 2547 |
HN1L,PLSCR1,LIFR,IL6ST,APPBP2 |
| 7.230e-03 | -4.93 | DOK5 (docking protein 5) | protein interactions | 55816 | 9 | 5 | 16036 | 2547 |
INSR,IGF1R,RET,EGFR,BNIP3L |
| 7.230e-03 | -4.93 | CD7 (CD7 molecule) | protein interactions | 924 | 9 | 5 | 16036 | 2547 |
CTSL,CPTP,NFKBIA,SECTM1,PIK3R1 |
| 7.230e-03 | -4.93 | ZMIZ1 (zinc finger, MIZ-type containing 1) | protein interactions | 57178 | 9 | 5 | 16036 | 2547 |
PIAS3,CACHD1,CNTNAP2,TBC1D4,TP53 |
| 7.239e-03 | -4.93 | Erlotinib Action Pathway | SMPDB pathways | SMP00472 | 3 | 3 | 978 | 190 |
EGFR,ABCB1,ABCG2 |
| 7.252e-03 | -4.93 | sphingolipid metabolic process | biological process | GO:0006665 | 139 | 32 | 16441 | 2455 |
UGT8,HEXB,P2RX7,ASAH1,TEX2,SGPL1,B4GALNT1,ITGB8,ARSG,A4GALT,SERINC2,BAX,NAGA,ALDH3A2,GM2A,CERS2,SPTLC2,ARSK,CPTP,SGPP1,KDSR,ALDH3B1,ALDH5A1,FA2H,PLPP3,PLA2G15,SAMD8,CTSA,GLB1,GLA,ST3GAL1,ARSB |
| 7.255e-03 | -4.93 | PID_E2F_PATHWAY | MSigDB lists | PID_E2F_PATHWAY | 73 | 19 | 17758 | 2588 |
SIRT1,CCNE2,SMARCA2,UXT,MYBL2,CDK1,CDKN2C,TP73,RB1,E2F7,CCNA2,CASP7,CES2,RBL1,RANBP1,E2F1,CDKN1B,HDAC1,CBX5 |
| 7.255e-03 | -4.93 | HALLMARK_CHOLESTEROL_HOMEOSTASIS | MSigDB lists | HALLMARK_CHOLESTEROL_HOMEOSTASIS | 73 | 19 | 17758 | 2588 |
FADS2,LGALS3,PLSCR1,S100A11,GUSB,PLAUR,FBXO6,PDK3,ALCAM,CXCL16,CTNNB1,ABCA2,CD9,TNFRSF12A,MAL2,LGMN,ETHE1,CPEB2,SEMA3B |
| 7.255e-03 | -4.93 | MORI_MATURE_B_LYMPHOCYTE_DN | MSigDB lists | MORI_MATURE_B_LYMPHOCYTE_DN | 73 | 19 | 17758 | 2588 |
TXN,MPP1,LITAF,KIF2C,CCNB1,ANLN,H2AFV,CDC25C,COX7A2,PRDX4,CAPN2,PAFAH1B3,NEK2,CKS1B,TAX1BP3,HMGA1,RAG1,CCNB2,PSMC1 |
| 7.260e-03 | -4.93 | dystrophin-associated glycoprotein complex | cellular component | GO:0016010 | 21 | 8 | 17570 | 2579 |
SNTA1,SGCE,MAGEE1,SNTB2,UTRN,SNTB1,SGCB,DAG1 |
| 7.269e-03 | -4.92 | CHN2 (chimerin 2) | protein interactions | 1124 | 6 | 4 | 16036 | 2547 |
RACGAP1,TGFBR1,ERBB3,AKT1 |
| 7.269e-03 | -4.92 | OSBPL6 (oxysterol binding protein-like 6) | protein interactions | 114880 | 6 | 4 | 16036 | 2547 |
PLK1,AURKA,ARRDC1,BLVRA |
| 7.269e-03 | -4.92 | PRX (periaxin) | protein interactions | 57716 | 6 | 4 | 16036 | 2547 |
EZR,DRP2,DAG1,PRX |
| 7.269e-03 | -4.92 | HIST1H2BH (histone cluster 1, H2bh) | protein interactions | 8345 | 6 | 4 | 16036 | 2547 |
IGSF8,CD81,SPRTN,ICAM1 |
| 7.269e-03 | -4.92 | PLPP3 (phospholipid phosphatase 3) | protein interactions | 8613 | 6 | 4 | 16036 | 2547 |
PTEN,BCAR1,PLPP3,BCL6 |
| 7.269e-03 | -4.92 | NDST1 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1) | protein interactions | 3340 | 6 | 4 | 16036 | 2547 |
NAAA,CPEB4,HLA-E,PLAUR |
| 7.269e-03 | -4.92 | HES6 (hes family bHLH transcription factor 6) | protein interactions | 55502 | 6 | 4 | 16036 | 2547 |
TLE1,TWIST1,HES1,PTEN |
| 7.269e-03 | -4.92 | NEXN (nexilin (F actin binding protein)) | protein interactions | 91624 | 6 | 4 | 16036 | 2547 |
CUL1,LGR4,HSPB1,CALM1 |
| 7.269e-03 | -4.92 | CDH3 (cadherin 3, type 1, P-cadherin (placental)) | protein interactions | 1001 | 6 | 4 | 16036 | 2547 |
CDH3,CTNND1,CTNNB1,CDH1 |
| 7.271e-03 | -4.92 | FTH1 (ferritin, heavy polypeptide 1) | protein interactions | 2495 | 49 | 15 | 16036 | 2547 |
CD99,SPP1,NR3C1,PCBP3,TP53,AURKA,BRD7,FTH1,KPNA2,IGSF8,AURKB,FXR2,PACSIN1,PCBP1,HSPB1 |
| 7.277e-03 | -4.92 | Cyclin A:Cdk2-associated events at S phase entry | REACTOME pathways | R-HSA-69656 | 66 | 18 | 8202 | 1235 |
CCNE2,PSMB4,PSME2,PSMD7,CUL1,PSMD10,PSME1,PSMA4,WEE1,RB1,CCNA2,PSMD1,PSMD3,PSMC2,CKS1B,CDKN1B,PSMC1,PSMA5 |
| 7.283e-03 | -4.92 | regulation of lipid biosynthetic process | biological process | GO:0046890 | 123 | 29 | 16441 | 2455 |
PRKAA2,SIRT1,SOD1,SORBS1,AKT1,PRKAA1,WDTC1,IDH1,PDGFB,POR,FGF19,PLIN5,SEC14L2,GPLD1,BMP2,PDGFA,PTGS2,PRKAG2,ATP1A1,MID1IP1,IGF1R,CYR61,PEX2,SLC27A1,SAMD8,GPER1,GFI1,CNEP1R1,ABCG1 |
| 7.287e-03 | -4.92 | epidermis development | biological process | GO:0008544 | 267 | 55 | 16441 | 2455 |
EXPH5,CASP3,USH1C,LGR4,GRHL2,ST14,SOX9,MCOLN3,LRP4,JAG2,CRABP2,TNFRSF19,TMC1,FZD6,PLS3,ELF3,ZDHHC21,CD109,PDGFA,IGF1R,CTGF,CTNNB1,GRHL1,SMO,CDH3,ERCC2,FLOT2,GFI1,ALDH3A2,HES1,SOD1,KLK5,SHARPIN,PPARA,TFAP2C,SCRIB,COL7A1,LDB2,SAV1,EGFR,GNAS,PITX2,INSR,AGPAT2,FA2H,FGFR2,CTSV,DBI,HDAC1,OVOL1,KLK7,HOXB13,PLOD3,GAB1,HOXC13 |
| 7.296e-03 | -4.92 | GSE27786_LSK_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_LSK_VS_CD8_TCELL_UP | 187 | 40 | 17758 | 2588 |
CASP3,TXN,TMTC3,ST14,SLC25A13,CUL1,DHRS3,FLT3,C16orf59,SPP1,METTL7A,SGK3,PLEKHF1,VAT1,IQGAP3,CITED2,PTPRE,C12orf75,B3GALT6,SHMT1,KIAA1841,STAU2,CBX6,CCDC34,CDCA2,CCNF,GLCE,PRDX4,MOSPD3,TRIM47,HAGHL,MATN2,MYLK,BMP1,AURKA,RELL1,TMEM159,TBC1D4,COL16A1,E2F8 |
| 7.296e-03 | -4.92 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP | 187 | 40 | 17758 | 2588 |
NKX3-1,UGT8,HEBP1,XYLT1,SERPINB9,PBX3,DDR1,DIRAS3,APLP2,RAB15,FAM46A,PAIP2B,CD22,MITF,AOX1,TPST1,SORL1,TSPAN13,KLF9,WBP4,TPCN1,SCN3A,GCNT1,OLFML2A,KCTD20,CR2,MGAM,SESN1,IRS2,GALNT3,BTG1,NEIL1,PRCP,MMP17,DTX4,SPRY4,SYT13,ANXA9,NR3C2,PHC1 |
| 7.296e-03 | -4.92 | GGGACCA,MIR-133A,MIR-133B | MSigDB lists | GGGACCA,MIR-133A,MIR-133B | 187 | 40 | 17758 | 2588 |
GAS2L1,TRIM2,ST13,TGFBR1,BCL2L1,BAHD1,TTYH3,NFAT5,GRM5,MECOM,CORO1B,IL6ST,PAPSS1,DNM2,TAGLN2,ACSL4,PACSIN1,RAG1,TRAM1,FLOT2,CERS2,DUSP1,SOCS5,KIAA0040,LPGAT1,YES1,CBL,GABARAPL1,USP6,CNTNAP1,RTN4RL1,TIMM8A,RAP2C,APPL2,AGBL5,RAB11FIP1,OTUB2,PPP2R5D,NIPA1,FAM134B |
| 7.296e-03 | -4.92 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN | 187 | 40 | 17758 | 2588 |
FAM89A,DHPS,CD82,NENF,SLC25A43,PHLDA1,BCAP31,ASPHD2,CD109,CPNE2,MGAT1,BDH1,CAPG,ETHE1,SGCB,C12orf75,ITM2C,NFE2L3,SHMT1,CTNNAL1,SLC39A8,C1GALT1C1,WHSC1,IGSF8,XRCC6BP1,POLD3,MAP3K6,SNX12,ADRBK2,PRIM1,AGPAT2,SH2D3C,DBI,C1orf21,IARS2,KIAA1804,FAM83D,MRPS28,TMEM120A,RUSC1 |
| 7.296e-03 | -4.92 | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDM_DN | 187 | 40 | 17758 | 2588 |
SUN1,S100A11,JKAMP,SLC41A1,KCTD12,NENF,CAMK1D,TMEM63A,IER3,ATP6V0B,RB1,SGK1,IRF2,SMYD5,NR2C1,IL1RAP,TMX1,SMAGP,ABCC1,TUBA4A,CERS2,ERMP1,MARK1,PSRC1,BCL9,SERTAD3,AK4,MEST,PRKRA,CYB5A,NIN,DDOST,WFS1,SPINT2,FGD6,HOXB13,NCAPG2,GLCCI1,LRRC57,CD33 |
| 7.311e-03 | -4.92 | Galactose-bd-like | interpro domains | IPR008979 | 78 | 20 | 18293 | 2672 |
GUSB,EPHA4,FURIN,FBXO2,FBXO6,EPHA1,CNTNAP2,DDR1,NRP2,CNTNAP1,EPHA10,SUCO,GLB1,FBXO44,GLB1L2,EPHB4,NTN1,FBXO27,DCBLD1,PCSK5 |
| 7.315e-03 | -4.92 | regulation of extent of cell growth | biological process | GO:0061387 | 102 | 25 | 16441 | 2455 |
SEMA6B,PLXNA1,CRABP2,ILK,ULK2,CDK5R1,MAP1B,SPP1,CDKL5,SEMA4D,DPYSL2,LIMK1,MEGF8,DNM2,NRG1,EFNA5,TNFRSF12A,CTTN,SEMA3G,PLXND1,NTN1,WNT3A,SEMA3A,L1CAM,SEMA3B |
| 7.315e-03 | -4.92 | positive regulation of calcium ion transport | biological process | GO:0051928 | 102 | 25 | 16441 | 2455 |
P2RX4,CASK,LGALS3,CALM1,CALM3,P2RX7,ATP1B1,PDGFB,CALM2,PLCG1,STIM1,HTT,WFS1,MYLK,PLCG2,BAX,TRPC1,PKD2,GPER1,CACNA1D,JAK3,TRPC3,F2R,HSPA2,DRD1 |
| 7.323e-03 | -4.92 | BARIS_THYROID_CANCER_DN | MSigDB lists | BARIS_THYROID_CANCER_DN | 58 | 16 | 17758 | 2588 |
LMO7,RECQL,INPP5D,GATA3,ERBB2,IL13RA1,CCND1,RB1,FNTA,TIMP1,IGF1R,CDH3,USP1,KLF5,UBE2C,IRF1 |
| 7.329e-03 | -4.92 | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | 227 | 47 | 17758 | 2588 |
GAA,CCDC109B,TRAPPC10,ALDH6A1,AASS,DHPS,IQGAP1,LRP4,PDIA5,FLOT1,GMPR,MPP5,SPR,CMTM6,ZFYVE9,SP100,RGS3,KCNK5,ADCK2,CRY2,TAGLN2,MCTP1,SEC61B,ZNF84,PLSCR1,SAT1,SPTLC2,PCTP,NDRG3,MYL12A,SP4,OPTN,ARHGAP24,ENDOD1,FYN,CDK19,HOXA9,ANXA9,TMEM8B,ARPC2,RGS14,ZMIZ1,MAD2L1BP,ARNT,MYL12B,PCSK5,PHC1 |
| 7.338e-03 | -4.91 | FURUKAWA_DUSP6_TARGETS_PCI35_UP | MSigDB lists | FURUKAWA_DUSP6_TARGETS_PCI35_UP | 68 | 18 | 17758 | 2588 |
OLFML2A,HLA-F,FXYD3,HERC5,DUSP4,HERC6,LYPD5,MDK,CNTNAP1,ALPP,ARHGEF37,C19orf66,ENPP5,SECTM1,MAPK11,EPB41L4A,SNED1,PARP9 |
| 7.338e-03 | -4.91 | ROSS_AML_OF_FAB_M7_TYPE | MSigDB lists | ROSS_AML_OF_FAB_M7_TYPE | 68 | 18 | 17758 | 2588 |
PCCB,FADS2,CMAS,SOD1,DRAP1,FHL2,RASA1,BMP2K,ITGA2B,NEO1,PDCD10,TIMP3,ANK1,PLOD2,NGFRAP1,GATA2,SERPINI1,MINPP1 |
| 7.341e-03 | -4.91 | cytokinetic process | biological process | GO:0032506 | 13 | 6 | 16441 | 2455 |
RACGAP1,AURKB,CNTROB,RHOA,SNX9,SNX18 |
| 7.341e-03 | -4.91 | response to water | biological process | GO:0009415 | 13 | 6 | 16441 | 2455 |
AKR1B1,COL18A1,PKD2,LRP11,TFAP2A,CD9 |
| 7.341e-03 | -4.91 | negative regulation of peptidyl-threonine phosphorylation | biological process | GO:0010801 | 13 | 6 | 16441 | 2455 |
CALM3,CALM2,SPRED1,DMTN,SPRY2,CALM1 |
| 7.349e-03 | -4.91 | GTCTTCC,MIR-7 | MSigDB lists | GTCTTCC,MIR-7 | 159 | 35 | 17758 | 2588 |
PAX6,ZNF395,CNOT8,BACE1,ABCG4,PBX3,MAPK4,EGR3,PLXNA1,HPCAL4,VPS26A,MAP3K9,ANKRD12,CNNM4,CRY2,ACSL4,PIK3CD,PIM1,PDE4D,SMYD5,CKAP4,TBC1D10B,CHSY3,ASXL1,ITCH,OXR1,SRRM3,SRSF5,ARF4,IRS2,KLF12,SLC4A4,UBE2D2,FAM83D,NR4A3 |
| 7.349e-03 | -4.91 | TIEN_INTESTINE_PROBIOTICS_6HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_6HR_DN | 159 | 35 | 17758 | 2588 |
RECQL,PACSIN2,ZNF395,HEXB,ETNK1,PLXNA1,NTAN1,SEPP1,EMP2,DNAJB9,RAB15,PSMD1,RABEP2,CALD1,TAX1BP3,SGK1,ARMCX6,CKAP4,AMOTL2,CENPA,MMD,RAPGEF2,FHL2,SRSF5,STEAP1,STX3,PITX2,BTG1,MPRIP,PPP2R5A,WWTR1,PSMC1,CPPED1,MELK,DOCK9 |
| 7.365e-03 | -4.91 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | 63 | 17 | 17758 | 2588 |
HMMR,GFPT1,CASP3,HSP90B1,PPP1R2,WHSC1,PRR7,DUSP5,DNAJB9,PDIA4,APOBEC3B,UAP1,DDHD2,UBE2J1,AURKA,FHL1,TRAM1 |
| 7.365e-03 | -4.91 | REACTOME_GLUCOSE_METABOLISM | MSigDB lists | REACTOME_GLUCOSE_METABOLISM | 63 | 17 | 17758 | 2588 |
PGM1,UGP2,ENO2,PFKFB2,SLC25A13,CALM1,PYGL,CALM3,PRKACA,CALM2,PFKL,GYS1,GOT1,MDH1,PHKA2,PHKG2,PPP2R5D |
| 7.365e-03 | -4.91 | GOLDRATH_IMMUNE_MEMORY | MSigDB lists | GOLDRATH_IMMUNE_MEMORY | 63 | 17 | 17758 | 2588 |
POU6F1,GOLIM4,SORBS1,IL15RA,CHCHD7,KCTD12,NCKAP1,ECI1,NR1D2,ABCB1,TMEM159,F2R,CHPT1,IL10RB,RPGR,MAPK12,DOCK9 |
| 7.379e-03 | -4.91 | Degradation of beta-catenin by the destruction complex | REACTOME pathways | R-HSA-195253 | 81 | 21 | 8202 | 1235 |
PSMB4,PSME2,AMER1,PSMD7,CUL1,PSMD10,AES,TCF7,PSME1,PSMA4,PSMD1,PPP2R5A,CTNNB1,PSMD3,PSMC2,TLE1,HDAC1,PSMC1,PPP2R5D,CTBP1,PSMA5 |
| 7.392e-03 | -4.91 | MODULE_248 | MSigDB lists | MODULE_248 | 126 | 29 | 17758 | 2588 |
CASK,PAX6,ARHGEF11,CRYM,MPP1,SNTB2,STAT4,DGKA,PDCL,PRKCQ,YES1,APBA1,MERTK,DGKE,TXK,SOCS3,BCAR3,PLCG1,JAK1,PDLIM3,WFS1,CDH3,PITPNA,CNGA1,DLG3,JAK3,SHROOM2,ZBTB33,CYP1B1 |
| 7.443e-03 | -4.90 | regulation of morphogenesis of a branching structure | biological process | GO:0060688 | 52 | 15 | 16441 | 2455 |
PDGFA,CTNNB1,HOXB7,LGR4,FGFR2,BMP7,SOX9,ETV5,SMO,NTN4,TACSTD2,SOX8,ETV4,SHOX2,SIX4 |
| 7.452e-03 | -4.90 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin | KEGG pathways | ko00534 | 24 | 9 | 6908 | 1076 |
B3GALT6,HS6ST1,XYLT2,XYLT1,HS3ST3B1,EXT2,NDST3,HS6ST3,GLCE |
| 7.452e-03 | -4.90 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin | KEGG pathways | hsa00534 | 24 | 9 | 6908 | 1076 |
B3GALT6,HS6ST1,XYLT2,XYLT1,HS3ST3B1,EXT2,NDST3,HS6ST3,GLCE |
| 7.463e-03 | -4.90 | synapse part | cellular component | GO:0044456 | 534 | 99 | 17570 | 2579 |
DOC2A,LAMP1,GRIK2,SLC2A8,EPHA4,FBXO2,ERBB2,LGI3,KCTD12,BCL2L1,PJA2,PRR7,PICK1,GRM5,NCS1,CABP1,DPYSL2,DLG1,DNM2,PPP1CA,CTTN,DLG3,F2R,CPE,CLCN3,DMTN,SEPT6,UTRN,CLSTN1,SYP,PRKAR2B,SLC17A5,TANC1,DAG1,ARF4,TRIM9,ATP1A1,FYN,GRID2IP,DNM1L,MAP2,SIPA1L1,ITPKA,RGS14,APBA2,NRGN,LZTS1,FARP1,CPEB4,CALB2,EPS8,LRP4,STRN4,GABRG2,SLC1A3,APBA1,SRPX2,SNTA1,ANK1,ADD3,ITGA3,ADORA1,ZNRF2,PTEN,CDK16,ANKS1B,RIMS3,FLRT3,MAGEE1,CPLX1,NPTN,MAP3K7,CAMK2G,RIMS2,DLGAP1,P2RX4,MOB4,SYPL1,RAB3B,CASK,SHARPIN,GRIN1,VAMP3,SCRIB,ILK,CDK5R1,MAP1B,IL1R1,GABRD,SYT7,HTT,ITPR1,NETO2,ARRB1,GRIN2D,GPER1,L1CAM,RUSC1,DRD1 |
| 7.475e-03 | -4.90 | CCCNNGGGAR_V$OLF1_01 | MSigDB lists | CCCNNGGGAR_V$OLF1_01 | 303 | 60 | 17758 | 2588 |
LASP1,ARMCX3,UPF3B,NF2,CHCHD7,SLC41A1,THRA,COL18A1,SORBS3,FAM198B,TRIB2,APBA1,BAHD1,DDR1,GNB2,ICAM1,SYTL2,MECOM,NEO1,SNX13,VASP,CA2,RGS3,VASN,VAT1,STEAP3,SEMA3G,EPB41L4B,PACSIN1,ETV4,TIAM1,TBC1D10B,DPYSL5,PDGFC,TRIM8,PLEKHA6,ELK3,TNIP1,FOXJ2,CBX6,C2orf69,DUSP4,PNKD,SP4,ABR,EPN3,MAGED2,ATP1A1,H1F0,AXL,SLC9A6,NFKBIA,C1orf21,GRIN2D,ANXA9,NDFIP1,AIFM3,STARD13,JARID2,DMPK |
| 7.478e-03 | -4.90 | CASK (calcium/calmodulin-dependent serine protein kinase (MAGUK family)) | protein interactions | 8573 | 77 | 21 | 16036 | 2547 |
KCNJ12,CASK,IL15RA,GRIK2,SNTB2,EPS8,SDC4,BNIP3L,P2RX7,IL18,F11R,CNTNAP2,ERBB2IP,APBA1,TANC1,SDC1,SH2D4A,ARHGEF26,PTGS2,PLK2,DLG1 |
| 7.478e-03 | -4.90 | FH (fumarate hydratase) | protein interactions | 2271 | 77 | 21 | 16036 | 2547 |
PGM1,GNPDA1,HEXB,SOD2,EZR,PYGL,NANS,ISOC2,PKM,H2AFV,DAZAP1,WDFY1,ALDH5A1,OXCT1,CALD1,PAPSS1,CAB39,AHCY,GOT1,PIM1,ANXA11 |
| 7.505e-03 | -4.89 | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | REACTOME pathways | R-HSA-168643 | 47 | 14 | 8202 | 1235 |
TXN,IRAK1,RIPK2,TAB3,ITCH,CASP9,NOD2,P2RX7,MAPK11,MAPK13,BCL2L1,MAP3K7,CASP4,MAPK12 |
| 7.513e-03 | -4.89 | malignant_peripheral_nerve_sheath_tumour | COSMIC cancer mutations | malignant_peripheral_nerve_sheath_tumour | 39 | 12 | 17775 | 2585 |
RB1,SS18,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR |
| 7.513e-03 | -4.89 | central_nervous_system-thalamus-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-oligodendroglioma_Grade_III | 39 | 12 | 17775 | 2585 |
MYO5B,PLEKHG6,HS6ST1,PARP12,JAK1,TP53,PDE5A,FZD5,TIAM1,ABCA1,TUBA4A,PCSK5 |
| 7.518e-03 | -4.89 | CREB phosphorylation through the activation of Ras | REACTOME pathways | R-HSA-442742 | 29 | 10 | 8202 | 1235 |
CALM2,RASGRF1,RPS6KA2,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D,RPS6KA3,CAMK2G |
| 7.522e-03 | -4.89 | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDM_UP | 193 | 41 | 17758 | 2588 |
ELK4,CD99,RECQL,PAPSS2,DNAJC3,ERCC6L,NES,TXNDC9,GTF3A,CDH1,BDH1,FAM13B,IRF2,STEAP3,KLF9,PXMP4,RAG1,TIAM1,S100A6,DPYSL5,PTPN18,PSRC1,TIMP2,TEP1,TNS1,UBAC1,IDH1,OSBPL2,IRS2,LIMK1,ZNF704,ZDHHC7,RPL22,SERPINB1,MIIP,PRR15,TOB1,RAB3IL1,DMPK,FAM134B,ABCG1 |
| 7.522e-03 | -4.89 | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | 193 | 41 | 17758 | 2588 |
SUN1,CAST,FAM134A,EFHD2,TEX2,DPP8,RSAD1,SLC25A36,ATG4A,RCN1,DOPEY2,ANK1,XYLT2,DLG1,PPP6R1,ADCK3,TCFL5,PIP4K2C,STMN3,DNAJB14,EPHA1,ERBB2IP,DAG1,DDX23,AMZ2,MAN2A2,MMP15,AP1AR,POPDC3,RCBTB2,PRDX3,LIMK1,APPL2,FAM117A,MRPS28,CABIN1,ACADM,NDE1,TMEM14A,PCSK5,DOCK9 |
| 7.522e-03 | -4.89 | GSE15930_STIM_VS_STIM_AND_IL-12_72H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_72H_CD8_T_CELL_DN | 193 | 41 | 17758 | 2588 |
GAA,HSPG2,NQO1,NLRX1,MORC4,PBX3,FLT3,KTN1,LTBP3,RAD23A,WWP2,IER3,METTL7A,SELK,NFU1,MYH14,TAGLN2,NTN1,MYT1,IL1RAP,DVL2,LOC81691,RFK,WNT10B,PIP4K2C,UBE2A,LITAF,KDELR3,NKAIN1,IFIT3,GABARAPL1,IL1R1,IRS2,SCARB2,SWAP70,SLC25A4,SYT7,TIMM8A,EFNA5,PRR15,FGD1 |
| 7.522e-03 | -4.89 | GSE17721_POLYIC_VS_CPG_6H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDM_UP | 193 | 41 | 17758 | 2588 |
GRN,ACVR1,ATP9A,ATP8A1,ARHGEF7,CUL4B,HEXB,SUDS3,CNTROB,GPSM2,SPSB1,PSIP1,LMNA,UHRF1BP1L,SESN3,WDFY1,RNF128,CTSC,FRYL,PLCG2,N4BP3,CDKN1B,RP2,TMEM37,CTDSP2,NAGA,CAMK2G,PVRL4,SUN2,ITCH,BCL9,CDA,RAB3IP,RPL12,TIMM8A,CORO1C,RAP2C,SPINT2,ACADM,RGS14,TOB1 |
| 7.522e-03 | -4.89 | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN | MSigDB lists | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN | 193 | 41 | 17758 | 2588 |
KLF2,EPAS1,ELOVL7,PTTG1,C5orf30,KCTD12,DHRS3,CYP39A1,MXD1,ACAP2,GNB5,ARSG,FAM160A2,KLF3,RFX5,IFIT1,C10orf54,CITED2,P2RX4,TMTC1,KCNIP3,OXR1,UTRN,PDE5A,EPHA1,FOS,ATP10D,ALDH3B1,KLF12,TTC12,ABCB1,SERPINI1,IRF7,IFIH1,TMEM14A,CPEB2,TOB1,ABCA1,ESYT2,ABCG1,XDH |
| 7.522e-03 | -4.89 | GSE17721_CTRL_VS_LPS_0.5H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_0.5H_BMDM_DN | 193 | 41 | 17758 | 2588 |
SUN1,MAN2B2,MYL9,SIGIRR,SH3D19,TXNDC9,OSR2,NUCB2,PHLDA1,SLC9A3R2,SIX4,PPP2R3A,SYTL2,ZYX,TIMP1,ZFP36,RPL39,VASN,RAG1,PTPRE,SMYD5,SPRY2,TTLL1,PHKG2,TSPAN33,SMAGP,MBP,SHARPIN,PLEKHO1,PRKCQ,PRRC1,PCTP,PLEKHB1,LRRC42,TMEM50B,MMP17,SLC27A1,LTBP2,NUP37,TC2N,TLL2 |
| 7.533e-03 | -4.89 | REACTOME_SIGNALING_BY_NOTCH | MSigDB lists | REACTOME_SIGNALING_BY_NOTCH | 94 | 23 | 17758 | 2588 |
CCNC,HES1,ADAM17,TNRC6C,LFNG,HDAC11,TP53,FURIN,CUL1,JAG2,RAB6A,NOTCH2,HDAC6,DNER,HDAC9,CCND1,E2F1,DTX4,ARRB1,TLE1,HDAC1,NOTCH3,TMED2 |
| 7.536e-03 | -4.89 | IL6ST (interleukin 6 signal transducer) | protein interactions | 3572 | 36 | 12 | 16036 | 2547 |
KCNIP3,JAK1,PLAUR,IL6ST,IL31RA,PIK3R1,OSMR,TLE1,ERBB2,ERBB3,LIFR,SOCS3 |
| 7.556e-03 | -4.89 | positive regulation of RNA metabolic process | biological process | GO:0051254 | 1488 | 255 | 16441 | 2455 |
CCNC,ACVR1,TRIM24,AGRN,LGR4,EPAS1,TRIM5,CNOT8,HEXB,RET,GATA3,MORF4L2,CAMK1D,CCNB1,PDGFB,TFAP2E,TP73,EPCAM,HELZ2,HSF2,CTNNB1,GRHL1,NPNT,ZFP36,PSMC2,IL31RA,MITF,FOSB,ELF5,DNM2,IRF2,ASH2L,ARNT2,MYBL1,ZNF462,THRB,NEK4,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,ASXL1,NFE2L1,TFAP2C,EAF2,LDB2,SAV1,ARF4,SEC14L2,AHRR,MDK,KLF12,TBX1,NOD2,HDAC1,RNASEL,TRAF5,F2RL1,E2F8,PSMC1,MAFF,HOXC13,NR2C2,DDX58,KLF2,RUNX2,CDKN1C,PPP1R12A,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,BMP2,TFAP4,RB1,DAZAP1,CYR61,GATA2,EBF4,PRKCI,MDFIC,MYDGF,WNT3A,MAPK7,NUP85,ELK3,RGMB,SALL4,STAT4,FHL2,MYBL2,ELK1,ILK,TP53INP2,KDM3A,NFIB,EGFR,ONECUT1,NCOA3,SERTAD2,INSR,ETS2,PLPP3,SETD3,NFKBIA,PIAS2,NLRC5,NR4A2,TOB1,RARG,RPS6KA3,TMEM173,KLF7,IRF1,RAD21,PAX6,ARMCX3,GRHL2,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,CCNL1,LPIN3,SS18,CCNA2,CDH1,SP100,LMO4,SMO,DAB2IP,ZBTB49,TWIST1,NOTCH3,NFKB2,F2R,ETV4,MED30,DVL2,CTH,SIRT1,PSRC1,RIPK2,TCEB2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,EBF2,FZD7,NFIX,JADE1,HSF4,RBL1,STAT6,WWTR1,STAT1,KLF5,IRF7,NRG1,AKNA,ARNT,ATMIN,GLIS3,ANXA3,PINK1,NKX3-1,TNRC6C,CKAP2,TAB3,ARHGEF11,TRAF2,PBX3,TGFBR1,HMGN3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,GBX2,IRF2BPL,TOP2A,E2F7,IRAK1,PTEN,BMP7,MCF2L,TOX2,GTF2F2,TFAP2A,TRIM21,BRD7,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,NFE2L3,HES1,DCAF6,CASK,PLSCR1,WNT10B,HMGN5,NR3C1,BCL9,NR4A1,TEF,PIK3R1,GRIN1,PPARA,RGCC,MAML2,RUNX3,YES1,FOS,ABLIM2,BCL10,TXK,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,NR1D2,ACVRL1,E2F1,NR4A3,ARRB1,PKD2,GPER1,HMGA1,SOX8,ZMIZ1,OSR1,FZD5,CD81,SHOX2,USF2,AHR,FOXA1,USP16,RGMA |
| 7.574e-03 | -4.88 | Pkinase_C | pfam domains | PF00433 | 29 | 10 | 16629 | 2504 |
RPS6KA2,AKT1,CIT,RPS6KA1,STK38,SGK3,SGK1,PRKCQ,PKN1,RPS6KA3 |
| 7.579e-03 | -4.88 | PTPN11 (protein tyrosine phosphatase, non-receptor type 11) | protein interactions | 5781 | 157 | 37 | 16036 | 2547 |
LGALS3,MPZL1,INPP5D,RET,ERBB2,EFHD2,CD274,DDR1,SIRPA,CYP1A1,IGF1R,CTNNB1,OXCT1,IL6ST,PLCG2,ERBB3,SPRY2,FRS3,PPIF,PIK3R1,CBL,BCAR1,LEPR,EGFR,SOCS3,IRS2,PLCG1,FYN,INSR,JAK1,AXL,STAT1,LRRK1,MAP3K5,LIFR,GAB1,CD33 |
| 7.583e-03 | -4.88 | Focal Adhesion | WikiPathways | WP306 | 184 | 43 | 4455 | 729 |
TNK1,PPP1R12A,ITGA6,ERBB2,TESK2,MAPK4,PDGFB,ITGA2B,CCND1,PDGFA,PAK6,ZYX,SPP1,RAC2,VASP,ITGB8,IGF1R,ITGA3,PTEN,SHC3,PAK2,PIK3CA,PIK3CD,MAPK7,FARP2,PDGFC,RHOA,COL6A2,AKT1,PIK3R1,ILK,ELK1,BCAR1,EGFR,RHOB,TXK,PGF,FYN,ITGA7,MYLK,ITGAV,CAPN1,MAPK12 |
| 7.585e-03 | -4.88 | response to organic cyclic compound | biological process | GO:0014070 | 798 | 144 | 16441 | 2455 |
CASP3,TRIM24,SSH1,GATA3,IL18,ITPR2,CCNB1,PDGFB,SDC1,CALM2,CYP1A1,CTNNB1,CTGF,DPYSL2,FOSB,DNM2,ABCA2,CLDN4,ASH2L,ARNT2,TIPARP,SP5,CYP1B1,THRB,SOD1,CITED4,CASP9,EZR,AGO4,PRKAR2B,PRKRA,IDH1,MDK,MAP2,AREG,NOD2,NR2C2,DDX58,GRN,KLF2,DGKQ,PRKAA1,CALM3,BMP2,CALR,TFAP4,SPP1,CA2,IGF1R,PAK2,PIM1,EPHX1,PAQR7,CALM1,ELK1,EGFR,FAS,FECH,GNAS,MMP15,NCOA3,NFKBIA,AURKA,NR4A2,TRPC3,RARG,TMEM173,DRD1,NQO1,IL15,FOXM1,THRA,ERBB2,P2RX7,BCL2L1,PRKACA,CCND1,CCNA2,CDH1,RALB,SRR,SMO,CDKN1B,GOT1,IFIT1,PDE4D,OSBPL7,CDKN2D,NR2C1,AKT1,RIPK2,PTPRU,DMTN,PRKCQ,SOCS3,DUOX1,PTGS2,ATP1A1,STAT1,NR3C2,LIFR,ANXA3,NKX3-1,HSP90B1,CTSB,SERPINB9,GNAL,FLOT1,SELL,GABRG2,TGFBR1,ETS1,ICAM1,PTEN,BMP7,CST3,BAX,IGFBP2,KLF9,CITED2,DUSP1,HCN3,P2RX4,RHOA,SHMT1,WNT10B,NR3C1,NR4A1,RAPGEF2,GRIN1,PPARA,FOS,CD83,GPLD1,RGS9,TIMP3,NR1D2,CTSV,NR4A3,HOXB13,GPER1,ARSB,PTGES,FOXA1 |
| 7.610e-03 | -4.88 | cell cortex part | cellular component | GO:0044448 | 120 | 28 | 17570 | 2579 |
MYO5B,LASP1,NF2,MPP1,DMTN,SEPT6,DSTN,FLOT1,EZR,PLS1,ANLN,SPTB,CAPN2,PLEKHH2,SCNN1A,CDH1,STIM1,RALB,LLGL2,CALD1,EXOC8,PKD2,SPTBN5,CTTN,SHROOM2,MYRIP,FLOT2,GM2A |
| 7.623e-03 | -4.88 | skeletal system morphogenesis | biological process | GO:0048705 | 211 | 45 | 16441 | 2455 |
INPPL1,RUNX2,GRHL2,HSPG2,HOXB7,THRA,SOX9,RAB23,P2RX7,PHOSPHO1,TGFBR1,OSR2,FAM101B,DHRS3,HOXB2,SIX4,SGPL1,CTGF,CTNNB1,IMPAD1,BMP7,MEGF8,DLG1,TFAP2A,TWIST1,TIPARP,SP5,MDFI,CYP26B1,SPEF2,WNT10B,FMN1,PRKRA,ZFAND5,GNAS,COL13A1,FGFR2,TBX1,NAB2,FGF18,BMP1,CSGALNACT1,OSR1,SHOX2,RARG |
| 7.629e-03 | -4.88 | p38MAPK events | REACTOME pathways | R-HSA-171007 | 13 | 6 | 8202 | 1235 |
MAPKAPK2,MAPK11,MAPK13,RALB,MAPKAPK3,MAPK12 |
| 7.629e-03 | -4.88 | Repression of WNT target genes | REACTOME pathways | R-HSA-4641265 | 13 | 6 | 8202 | 1235 |
HDAC1,TLE1,AES,TCF7,CTNNB1,CTBP1 |
| 7.629e-03 | -4.88 | CLEC7A (Dectin-1) induces NFAT activation | REACTOME pathways | R-HSA-5607763 | 13 | 6 | 8202 | 1235 |
CALM2,CALM3,ITPR2,ITPR3,ITPR1,CALM1 |
| 7.641e-03 | -4.87 | HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDESCATALYZING_TRANSMEMBRANE_MOVEMENT_OF_SUBSTANCES | MSigDB lists | HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDESCATALYZING_TRANSMEMBRANE_MOVEMENT_OF_SUBSTANCES | 39 | 12 | 17758 | 2588 |
TAPBP,ATP1A1,ATP7B,ABCG2,ATP8B1,ATP1B1,ATP1B3,ATP6V1C1,ATP2B1,ABCD4,ABCG1,ABCC1 |
| 7.641e-03 | -4.87 | DELPUECH_FOXO3_TARGETS_DN | MSigDB lists | DELPUECH_FOXO3_TARGETS_DN | 39 | 12 | 17758 | 2588 |
PITX2,ZWINT,AREG,FOXM1,H1F0,PRC1,NEK2,AURKA,KIF22,NUSAP1,UBE2C,SMC4 |
| 7.641e-03 | -4.87 | SPINDLE | MSigDB lists | SPINDLE | 39 | 12 | 17758 | 2588 |
DLGAP5,CDC20,PRC1,KIF23,TUBG1,AURKA,BUB1,KNTC1,NDE1,KIF11,CDK1,SAC3D1 |
| 7.641e-03 | -4.87 | PROTEIN_OLIGOMERIZATION | MSigDB lists | PROTEIN_OLIGOMERIZATION | 39 | 12 | 17758 | 2588 |
ALDH5A1,INSR,IGF1R,IRAK1,AASS,AMFR,MAP3K11,TP53,BAX,NOD2,CDA,BCL10 |
| 7.656e-03 | -4.87 | OTU | pfam domains | PF02338 | 13 | 6 | 16629 | 2504 |
OTUD5,YOD1,OTUD1,ZRANB1,OTUD6B,ALG13 |
| 7.656e-03 | -4.87 | Peptidase_C1 | pfam domains | PF00112 | 13 | 6 | 16629 | 2504 |
CTSL,CTSZ,TINAGL1,CTSC,CTSB,CTSV |
| 7.668e-03 | -4.87 | SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1) | protein interactions | 6654 | 63 | 18 | 16036 | 2547 |
BIN1,SORBS1,NF2,EPS8,ERBB2,CBL,SNX9,RANBP9,EPS8L2,EGFR,SH3KBP1,PLCG1,FYN,SNX18,LRRK1,ERBB3,PACSIN1,GAB1 |
| 7.668e-03 | -4.87 | PRKCG (protein kinase C, gamma) | protein interactions | 5582 | 63 | 18 | 16036 | 2547 |
DDX58,IBTK,TRIM5,HABP4,GRIN1,RANBP9,GRM5,PICK1,TOP2A,NOXA1,ADRBK1,GRIN2D,NRGN,TIAM1,AFAP1,SCN3A,OCLN,DVL2 |
| 7.672e-03 | -4.87 | - | gene3d domains | 2.60.120.260 | 73 | 20 | 9988 | 1574 |
GUSB,EPHA4,FURIN,FBXO2,FBXO6,EPHA1,CNTNAP2,DDR1,NRP2,CNTNAP1,EPHA10,SUCO,GLB1,FBXO44,GLB1L2,EPHB4,NTN1,FBXO27,DCBLD1,PCSK5 |
| 7.678e-03 | -4.87 | MCCC1 (methylcrotonoyl-CoA carboxylase 1) | protein interactions | 56922 | 16 | 7 | 16036 | 2547 |
KIF5B,IFIT1,LGALS3,GCAT,CUL4B,EEF1D,MCCC2 |
| 7.678e-03 | -4.87 | CHIA (chitinase, acidic) | protein interactions | 27159 | 16 | 7 | 16036 | 2547 |
UBAC1,HPS3,NDE1,SLC2A8,GNB2,GNAL,FAM63A |
| 7.678e-03 | -4.87 | IGF1 (insulin-like growth factor 1 (somatomedin C)) | protein interactions | 3479 | 16 | 7 | 16036 | 2547 |
NOV,IGFBP2,IDE,IGF1R,IGFBP6,CTSB,E2F1 |
| 7.678e-03 | -4.87 | Bub1 (budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)) | protein interactions | 12235 | 16 | 7 | 16036 | 2547 |
BUB1,NUF2,ZWINT,PDE4D,SPC25,CDC20,NDC80 |
| 7.684e-03 | -4.87 | phagocytic vesicle membrane | cellular component | GO:0030670 | 53 | 15 | 17570 | 2579 |
LAMP1,HLA-B,ANXA3,ATP6V0B,RAC2,OCRL,HLA-E,HLA-F,RAB31,RAB11FIP1,RAB23,RAB20,HLA-C,RAB38,HLA-A |
| 7.692e-03 | -4.87 | reactive oxygen species biosynthetic process | biological process | GO:1903409 | 25 | 9 | 16441 | 2455 |
P2RX4,DUOX1,SOD1,CYP1A1,NQO1,AKT1,SLC7A2,SPR,CYP1B1 |
| 7.692e-03 | -4.87 | embryonic placenta morphogenesis | biological process | GO:0060669 | 25 | 9 | 16441 | 2455 |
NCOA3,GRHL2,CDKN1C,CYR61,FGFR2,ST14,SPINT2,FZD5,SOCS3 |
| 7.704e-03 | -4.87 | NFKB1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) | protein interactions | 4790 | 152 | 36 | 16036 | 2547 |
TXN,NFKBIE,TSC22D3,CD82,CUL4B,PSMD10,NKRF,COMMD5,PRKACA,ETS1,ELF3,NOV,CTNNB1,PPME1,ZFP36,IRF2,MXD3,NFKB2,TNIP1,NR3C1,NR4A1,FOS,PSMA4,SOCS3,NCOA3,STAT6,NFKBIA,DCUN1D1,E2F1,AURKA,HDAC1,KLF5,NFKBIZ,HMGA1,RGS14,IRF1 |
| 7.723e-03 | -4.86 | steroid hormone mediated signaling pathway | biological process | GO:0043401 | 57 | 16 | 16441 | 2455 |
THRB,NKX3-1,NR3C1,NR4A1,THRA,PPARA,NR1D2,BMP7,NR4A3,NR4A2,GPER1,NR2C1,RARG,NR3C2,PAQR7,NR2C2 |
| 7.736e-03 | -4.86 | GSE17721_LPS_VS_CPG_4H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDM_UP | 199 | 42 | 17758 | 2588 |
SPRED1,RUNX2,PARP12,UPF3B,IL15,AASS,ETNK1,C5orf30,RACGAP1,TNFSF9,PSIP1,MXD1,APPBP2,ICAM1,CHPF,MDFIC,PIM1,RAG1,SGCB,IL1RAP,TMEM9,PARP9,PVRL4,PLSCR1,NR3C1,PLEKHA7,CALCRL,ATP1B1,PDK3,RAB38,SAV1,FNDC3A,EGFR,ARHGAP35,PTGS2,CD8A,ACADSB,RBL1,STK39,ISOC1,JARID2,IRF1 |
| 7.739e-03 | -4.86 | V$ALPHACP1_01 | MSigDB lists | V$ALPHACP1_01 | 245 | 50 | 17758 | 2588 |
SORT1,UGP2,DLGAP5,TSC22D3,SLC25A13,CDCA3,DNAJB11,SEPT4,BAHD1,GNB2,SLC25A35,FLII,PCNA,CDH1,PPP1R10,SHC3,CALD1,FLRT3,GPC3,ICAM5,NEK2,USP1,SELK,GLB1L2,RP2,DLG3,FAR1,SPRY2,CKS2,SPATA20,HES1,KIAA1841,ASPM,PANK1,ELK1,LDB2,VCP,EBF2,SLC25A4,PRCP,DBI,FAM117A,TLE1,AGFG2,ETAA1,UBE2C,STARD13,NRGN,AFAP1,JARID2 |
| 7.741e-03 | -4.86 | positive regulation of RNA biosynthetic process | biological process | GO:1902680 | 1451 | 249 | 16441 | 2455 |
CCNC,ACVR1,TRIM24,AGRN,LGR4,EPAS1,TRIM5,HEXB,RET,GATA3,MORF4L2,CAMK1D,PDGFB,TFAP2E,TP73,EPCAM,HELZ2,HSF2,CTNNB1,GRHL1,NPNT,PSMC2,IL31RA,MITF,FOSB,ELF5,DNM2,IRF2,ASH2L,ARNT2,MYBL1,ZNF462,THRB,NEK4,PCGF5,SMARCA2,TRIM8,TNIP1,CITED4,ASXL1,NFE2L1,TFAP2C,EAF2,LDB2,SAV1,ARF4,SEC14L2,AHRR,MDK,KLF12,TBX1,NOD2,HDAC1,RNASEL,TRAF5,F2RL1,E2F8,PSMC1,MAFF,HOXC13,NR2C2,DDX58,KLF2,RUNX2,CDKN1C,PPP1R12A,ITGA6,SOX9,ETV5,PSIP1,LMNA,MECOM,ELF3,BMP2,TFAP4,RB1,CYR61,GATA2,EBF4,PRKCI,MDFIC,MYDGF,WNT3A,MAPK7,NUP85,ELK3,RGMB,SALL4,STAT4,FHL2,MYBL2,ELK1,ILK,TP53INP2,KDM3A,NFIB,EGFR,ONECUT1,NCOA3,SERTAD2,INSR,ETS2,PLPP3,SETD3,NFKBIA,PIAS2,NLRC5,NR4A2,RARG,RPS6KA3,TMEM173,KLF7,IRF1,RAD21,PAX6,ARMCX3,GRHL2,FOXM1,THRA,RPS6KA1,TP53,ERBB2,OSR2,CCNL1,LPIN3,SS18,CCNA2,CDH1,SP100,LMO4,SMO,DAB2IP,ZBTB49,TWIST1,NOTCH3,NFKB2,F2R,ETV4,MED30,DVL2,CTH,SIRT1,PSRC1,RIPK2,TCEB2,AKT1,FZD4,FOXJ2,SERTAD3,PRKCQ,PYGO1,GTF2A2,CD40,EBF2,FZD7,NFIX,JADE1,HSF4,RBL1,STAT6,WWTR1,STAT1,KLF5,IRF7,NRG1,AKNA,ARNT,ATMIN,GLIS3,ANXA3,PINK1,NKX3-1,CKAP2,TAB3,ARHGEF11,TRAF2,PBX3,TGFBR1,HMGN3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,GBX2,IRF2BPL,TOP2A,E2F7,IRAK1,PTEN,BMP7,MCF2L,TOX2,GTF2F2,TFAP2A,TRIM21,BRD7,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,NFE2L3,HES1,DCAF6,CASK,PLSCR1,WNT10B,HMGN5,NR3C1,BCL9,NR4A1,TEF,PIK3R1,GRIN1,PPARA,RGCC,MAML2,RUNX3,YES1,FOS,ABLIM2,BCL10,TXK,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,ACVRL1,NR1D2,E2F1,NR4A3,ARRB1,PKD2,GPER1,HMGA1,SOX8,ZMIZ1,OSR1,FZD5,CD81,SHOX2,USF2,AHR,FOXA1,USP16,RGMA |
| 7.752e-03 | -4.86 | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN | 182 | 39 | 17758 | 2588 |
PINK1,TMEM184B,SPC25,IL15RA,CDKN1C,ZCCHC24,CDCA3,PLAC1,NENF,GSTP1,FLT3,HPCAL4,RND1,IER3,RCN1,MGAT1,FICD,RRBP1,GOT1,MANF,LMAN1,FAH,TIMP2,KIF20A,CTNNAL1,CBX6,PDE5A,AURKB,PKMYT1,CCNF,CDK1,OPTN,MMP15,AXL,FAM149A,CCNB2,UBE2C,GAB1,ARHGEF4 |
| 7.762e-03 | -4.86 | PLK1 (polo-like kinase 1) | protein interactions | 5347 | 178 | 41 | 16036 | 2547 |
NUAK1,NDC80,ERCC6L,TP53,KIF23,KIF2C,FBXO6,CCNB1,DNAJB9,WEE1,CEP97,SRPX,CTNNB1,LMO4,PRC1,TUBG1,BUB1,SIMC1,MYT1,PSMA5,TRAK2,TUBA4A,PSMB4,ASPM,CDC20,PKMYT1,BORA,CDC25C,TP53I3,PSMA4,VCP,EGFR,TSC1,CDCA5,TRIOBP,MPP2,AURKA,GLB1,SGOL1,RAP1GAP,CTBP1 |
| 7.767e-03 | -4.86 | extrinsic component of plasma membrane | cellular component | GO:0019897 | 131 | 30 | 17570 | 2579 |
TNK1,FARP1,SERPINE2,ST14,IQGAP1,GNAL,RACGAP1,TEC,YES1,APC2,SNX9,GNA11,SYTL2,TXK,EPN3,GNAS,RGS9,FYN,CTNNB1,JAK1,CDH1,CDK16,SNX18,ARRB1,JAK3,TIAM1,SYK,SYTL3,S100A6,ESYT2 |
| 7.771e-03 | -4.86 | AAAGGAT,MIR-501 | MSigDB lists | AAAGGAT,MIR-501 | 121 | 28 | 17758 | 2588 |
CELSR2,LPGAT1,RET,RNF11,CUL1,KIF1C,UBE2Q1,LRRC1,SGPP1,NFIX,PITX2,RCN1,CACHD1,ACADSB,PIK3AP1,SYT7,SLC35B3,AMMECR1,MYLK,SRR,NR4A3,BCL6,PPP1CB,PCDH19,SCN3A,SEPHS1,CTDSP1,PHC1 |
| 7.771e-03 | -4.86 | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP | MSigDB lists | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP | 121 | 28 | 17758 | 2588 |
OTUD5,ING1,UPF3B,THRA,JKAMP,CAST,ETNK1,H2AFV,NFIB,STX3,SIRPA,RASA1,KIF5B,RCN1,PDGFA,DNAJC10,SCARB2,APLP2,TPST1,FAM63A,PIAS2,PGRMC1,SMO,TNPO2,PKD2,RELL1,PLD1,SLC35A1 |
| 7.771e-03 | -4.86 | ACAGGGT,MIR-10A,MIR-10B | MSigDB lists | ACAGGGT,MIR-10A,MIR-10B | 121 | 28 | 17758 | 2588 |
LTBP1,TRIM2,ASXL1,EPHA4,CTDSPL,RNF165,TFAP2C,FXR2,DOCK11,PPP1R14C,SDC1,NFAT5,SIX4,NRP2,APPBP2,NFIX,CTNNBIP1,DAZAP1,CSNK1G1,ZNF367,NR4A3,BCL6,CNNM4,KLF11,MAP3K7,USF2,ARNT,CAMK2G |
| 7.771e-03 | -4.86 | GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | MSigDB lists | GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 121 | 28 | 17758 | 2588 |
GFPT1,GAA,PPP1R2,GNPDA1,CYB5R2,SLC25A13,SLC25A27,PDIA5,BLVRA,SPR,LEPR,POR,EPM2A,FECH,DUOX1,ENPP1,INSR,ALDH5A1,SLC25A4,CYP4F11,DHRS2,WFS1,FDXR,PHKA2,LOXL1,PHKG2,GPX4,CYP1B1 |
| 7.783e-03 | -4.86 | ATP_BINDING | MSigDB lists | ATP_BINDING | 154 | 34 | 17758 | 2588 |
GALK1,TNK1,ACVR1,DYRK3,PINK1,PEX6,ABCG2,TP53,TGFBR1,ABCD4,DAPK2,CDKL5,PRKCI,ABCA2,MSH2,DAPK1,PIM1,MSH6,SMC4,ABCC1,SEPHS1,MARK1,PIF1,MAP3K6,STK17B,DGKE,STK17A,ACVRL1,STK38,ATP7B,PPP2R4,ABCB1,MAP3K5,DMPK |
| 7.795e-03 | -4.85 | P4Hc | smart domains | SM00702 | 16 | 7 | 9131 | 1455 |
PLOD3,EGLN3,PLOD2,P3H2,P4HA2,P4HA3,EGLN1 |
| 7.797e-03 | -4.85 | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN | MSigDB lists | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN | 89 | 22 | 17758 | 2588 |
SEC23A,PCOLCE,PPP1R12A,LGALS3,AGRN,MICB,FXYD3,CUL1,SPR,GSTP1,CASP4,HMGXB4,ABR,RAC2,CCDC6,KBTBD2,CAPG,PRKCI,SRP54,ITGAV,TRAM1,COL16A1 |
| 7.797e-03 | -4.85 | SWEET_KRAS_ONCOGENIC_SIGNATURE | MSigDB lists | SWEET_KRAS_ONCOGENIC_SIGNATURE | 89 | 22 | 17758 | 2588 |
LGALS3,IL18,TGOLN2,PDK3,NPC2,ATP1B1,SLC25A5,PHLDA1,SIRPA,GNS,CCND1,BTG1,VASP,PAFAH1B3,CST3,FAM3C,MANF,CITED2,SLC12A2,EEF1D,KDELR1,MDFI |
| 7.797e-03 | -4.85 | HINATA_NFKB_TARGETS_KERATINOCYTE_UP | MSigDB lists | HINATA_NFKB_TARGETS_KERATINOCYTE_UP | 89 | 22 | 17758 | 2588 |
SOD1,TNIP1,IL15,TAP1,LITAF,SOD2,ARHGDIB,SLC7A2,EGFR,ICAM1,CD83,GABARAPL1,BMP2,RAC2,GPRC5B,RND3,NFKBIA,CD9,CDH3,EFNA1,TIAM1,IRF1 |
| 7.811e-03 | -4.85 | entry into cell of other organism involved in symbiotic interaction | biological process | GO:0051806 | 87 | 22 | 16441 | 2455 |
LAMP1,PVRL4,CD55,ITCH,CTSB,CR2,F11R,DAG1,ICAM1,XPR1,WWP2,CD46,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1,CD81 |
| 7.811e-03 | -4.85 | movement in host environment | biological process | GO:0052126 | 87 | 22 | 16441 | 2455 |
LAMP1,PVRL4,CD55,ITCH,CTSB,CR2,F11R,DAG1,ICAM1,XPR1,WWP2,CD46,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1,CD81 |
| 7.811e-03 | -4.85 | entry into host cell | biological process | GO:0030260 | 87 | 22 | 16441 | 2455 |
LAMP1,PVRL4,CD55,ITCH,CTSB,CR2,F11R,DAG1,ICAM1,XPR1,WWP2,CD46,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1,CD81 |
| 7.811e-03 | -4.85 | entry into other organism involved in symbiotic interaction | biological process | GO:0051828 | 87 | 22 | 16441 | 2455 |
LAMP1,PVRL4,CD55,ITCH,CTSB,CR2,F11R,DAG1,ICAM1,XPR1,WWP2,CD46,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1,CD81 |
| 7.811e-03 | -4.85 | movement in environment of other organism involved in symbiotic interaction | biological process | GO:0052192 | 87 | 22 | 16441 | 2455 |
LAMP1,PVRL4,CD55,ITCH,CTSB,CR2,F11R,DAG1,ICAM1,XPR1,WWP2,CD46,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1,CD81 |
| 7.811e-03 | -4.85 | entry into host | biological process | GO:0044409 | 87 | 22 | 16441 | 2455 |
LAMP1,PVRL4,CD55,ITCH,CTSB,CR2,F11R,DAG1,ICAM1,XPR1,WWP2,CD46,SCARB2,IDE,ADRBK1,PVRL2,AXL,SIVA1,WWP1,ITGAV,NCAM1,CD81 |
| 7.829e-03 | -4.85 | actin filament | cellular component | GO:0005884 | 73 | 19 | 17570 | 2579 |
FMN1,DMTN,IQGAP1,EZR,YES1,AIF1L,APC2,LCP1,CORO1B,DPYSL3,TSC1,RAC2,FYN,ESPN,PKD2,CTTN,SHROOM2,COBL,MYO5A |
| 7.841e-03 | -4.85 | REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | MSigDB lists | REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | 30 | 10 | 17758 | 2588 |
MAPKAPK2,RPS6KA2,RPS6KA1,MAPK11,DUSP4,MAPK7,ELK1,FOS,PPP2R5D,RPS6KA3 |
| 7.841e-03 | -4.85 | REACTOME_NOD1_2_SIGNALING_PATHWAY | MSigDB lists | REACTOME_NOD1_2_SIGNALING_PATHWAY | 30 | 10 | 17758 | 2588 |
IRAK1,RIPK2,TAB3,CASP9,NOD2,MAPK11,MAPK13,MAP3K7,CASP4,MAPK12 |
| 7.841e-03 | -4.85 | PID_EPHRINB_REV_PATHWAY | MSigDB lists | PID_EPHRINB_REV_PATHWAY | 30 | 10 | 17758 | 2588 |
FYN,RGS3,PIK3R1,PIK3CA,EPHB4,YES1,MAP3K7,TIAM1,EFNB1,ITGA2B |
| 7.841e-03 | -4.85 | TING_SILENCED_BY_DICER | MSigDB lists | TING_SILENCED_BY_DICER | 30 | 10 | 17758 | 2588 |
SERPINA1,SLC4A4,CYR61,DHRS2,SERTAD4,PELI2,APOBEC3G,HOXB2,CPEB2,RASGRP1 |
| 7.841e-03 | -4.85 | PID_NECTIN_PATHWAY | MSigDB lists | PID_NECTIN_PATHWAY | 30 | 10 | 17758 | 2588 |
CTNNB1,CDH1,PVRL2,IQGAP1,PIK3R1,PIK3CA,F11R,ITGAV,PDGFB,FARP2 |
| 7.853e-03 | -4.85 | TGTATGA,MIR-485-3P | MSigDB lists | TGTATGA,MIR-485-3P | 143 | 32 | 17758 | 2588 |
ZMAT1,PPP4R4,RUNX2,TMEM184B,SOX9,C6orf106,UBE2Q1,NOTCH2,TRIB2,PHF1,CKAP5,RNF220,ANKS1B,CDK16,DAPK1,PDE4D,FAM134C,STK35,SIRT1,SYPL1,RHOA,NR3C1,CDYL,KBTBD8,ATP1B1,ZFAND5,ULK2,MAPKAPK2,TMEM30A,PIK3C2B,CTBP1,SNPH |
| 7.854e-03 | -4.85 | MHC class I protein binding | molecular function | GO:0042288 | 17 | 7 | 16491 | 2452 |
CD8A,TAPBP,TUBB4B,HLA-E,BCAP31,VCP,TAP1 |
| 7.855e-03 | -4.85 | RB_DN.V1_UP | MSigDB lists | RB_DN.V1_UP | 132 | 30 | 17758 | 2588 |
CCNE2,GCLM,HES1,PLEKHA6,FAM92A1,SLC2A8,THRA,DDIT4L,CRIP2,LYNX1,NANS,ARHGEF40,IFT27,TNFSF9,PRIM1,PCNA,TMEM54,ARTN,UBE2T,ZFP30,SIVA1,ALPK3,TUBG1,TNFRSF18,AHCY,MAPK13,MSH6,EPHX1,CTDSP1,SULF2 |
| 7.855e-03 | -4.85 | DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP | MSigDB lists | DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP | 132 | 30 | 17758 | 2588 |
SUN1,NEK4,GALK1,GCLM,SOD1,TXN,S100A11,IFITM3,KLK6,MRPS18A,EXT2,SPNS3,RAB2B,ICAM1,TP73,MAN2A2,CAPN2,SPP1,CXCL16,IDE,PFKL,RPL39,AXL,ARAP1,CMPK2,CITED2,CHPT1,UBE2C,CCDC38,EEF1D |
| 7.884e-03 | -4.84 | chromosome segregation | biological process | GO:0007059 | 217 | 46 | 16441 | 2455 |
SUN1,HJURP,SPC25,DLGAP5,CIT,PTTG1,NDC80,CDCA8,NUF2,KIF2C,CCNB1,SPDL1,CENPN,TOP2A,RB1,SETDB2,KIF14,NEK2,KIF22,BUB1,ERCC2,SMC4,PLK1,REC8,ZWINT,PSRC1,CENPC,PAPD7,VPS4B,CDCA2,NUSAP1,AURKB,SLC25A5,KIF11,SKA1,CDCA5,FAM83D,CHMP4B,CENPE,GEM,NUP37,RGS14,NDE1,SGOL1,ESPL1,RAD21 |
| 7.906e-03 | -4.84 | Prostate Cancer | WikiPathways | WP2263 | 109 | 28 | 4455 | 729 |
PLK1,CASP3,AKT1,NDRG1,CASP9,TP53,ELK1,FOS,BARD1,CDK1,RHEB,RASA1,CCND1,TSC1,RB1,NOXA1,JAK1,PTEN,E2F1,PIK3CA,MSH2,STAT1,BAX,ETV4,GAB1,SPRY2,FOXA1,MSH6 |
| 7.911e-03 | -4.84 | HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1) | protein interactions | 3113 | 87 | 23 | 16036 | 2547 |
LTBP1,QSOX1,GOLIM4,ASPM,HLA-F,EPHA4,TAF6L,DSE,B4GALT4,TNFSF9,QSOX2,DAG1,EFNB1,HLA-A,ATP13A2,SFXN1,PNPLA6,SORL1,EGFL7,HS3ST3B1,ERBB3,B4GALT3,DCBLD1 |
| 7.921e-03 | -4.84 | AAACCAC,MIR-140 | MSigDB lists | AAACCAC,MIR-140 | 105 | 25 | 17758 | 2588 |
PHF20L1,ACVR1,MMD,NR3C1,OSTM1,UBASH3B,BCL9,CIT,SLC25A13,STRADB,YES1,TP53INP2,C3orf58,USP6,PITX2,PHYHIP,MGAT1,C1orf21,REEP1,SRR,GYS1,RTKN2,HSPA13,PRIMA1,EHD1 |
| 7.925e-03 | -4.84 | multicellular organism growth | biological process | GO:0035264 | 82 | 21 | 16441 | 2455 |
KLF2,GRHL2,ADD1,CDKN1C,RC3H2,CCM2,WDTC1,TP53,ICMT,APBA1,STIL,GNAS,NCOA3,FGFR2,WWTR1,SMO,PDE4D,ERCC2,APBA2,SLC12A2,RARG |
| 7.925e-03 | -4.84 | renal tubule development | biological process | GO:0061326 | 82 | 21 | 16441 | 2455 |
HES1,LGR4,FMN1,SOX9,DCHS1,GATA3,ILK,IRX3,BMP2,CTNNBIP1,FAT4,CTNNB1,NPNT,GPC3,DLG1,STAT1,PKD2,TACSTD2,SOX8,OSR1,ADAMTS16 |
| 7.940e-03 | -4.84 | mannosyl-glycoprotein N-acetylglucosaminyltransferases | BIOCYC pathways | META_PWY-7426 | 8 | 5 | 907 | 172 |
MAN2A2,MGAT1,MGAT4A,MGAT5,MGAT4B |
| 7.943e-03 | -4.84 | GAB1 signalosome | REACTOME pathways | R-HSA-180292 | 102 | 25 | 8202 | 1235 |
TNRC6C,AKT1,NR4A1,CASP9,PIK3R1,ERBB2,NRG2,AGO4,PHLPP1,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,PTEN,FGFR2,PHLPP2,FGF18,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1 |
| 7.950e-03 | -4.83 | C-type lectin receptors (CLRs) | REACTOME pathways | R-HSA-5621481 | 123 | 29 | 8202 | 1235 |
PSMB4,TAB3,PSME2,CALM1,PSMD7,PSMD10,CALM3,CUL1,PSME1,ITPR2,ITPR3,PRKACA,PSMA4,BCL10,CALM2,FYN,PSMD1,PSMD3,NFKBIA,PLCG2,PAK2,PSMC2,ITPR1,UBE2D2,MAP3K7,NFKB2,PSMC1,SYK,PSMA5 |
| 7.954e-03 | -4.83 | GSE2706_R848_VS_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_LPS_8H_STIM_DC_DN | 171 | 37 | 17758 | 2588 |
CTHRC1,CCDC109B,TTC39B,IL15,SDC4,RGS20,UBE2Z,PDIA3,GALM,PATL2,PGAP1,PRRG4,NRP2,PLS3,CAPN2,GNS,BTG3,NTN1,SNX10,LAMP3,PRSS23,KIAA0040,ERP44,FNDC3A,TCN2,CRISPLD2,GNPTAB,RAP2C,RAB11FIP1,TMOD2,PLD1,RARG,COBL,CPEB2,ESYT2,WDR63,ABCG1 |
| 7.956e-03 | -4.83 | transferase activity, transferring glycosyl groups | molecular function | GO:0016757 | 275 | 56 | 16491 | 2452 |
UGT8,PARP12,LFNG,PARP14,GALNT12,XYLT1,HEXB,MGAT5B,POMGNT1,B4GALT4,EXT2,ART5,CHPF,B4GALNT1,B3GALNT1,TYMP,FUT2,MGAT1,A4GALT,XYLT2,MGAT4A,ALG13,FUT8,FUT1,GYS1,RPN2,STT3B,TIPARP,MGAT5,PARP9,GCNT1,CHSY3,B3GALT6,PIGC,SIRT1,B3GNT7,B3GNT2,MGAT4B,PARP4,GYLTL1B,PYGL,C1GALT1C1,GALNT7,B3GALNT2,GLT8D2,GALNT3,DDOST,CSGALNACT1,ALG2,B4GAT1,PLOD3,POMT1,B4GALT3,ST3GAL1,POMGNT2,KDELC2 |
| 7.960e-03 | -4.83 | V$ZF5_01 | MSigDB lists | V$ZF5_01 | 228 | 47 | 17758 | 2588 |
LAMP1,SPRED1,MPZL1,ARHGEF7,ADO,KLC2,KCTD12,KIF2C,VPS26A,KCTD15,ITGA3,FAM160A2,XYLT2,FUT8,DNM2,SORL1,TNPO2,HEXIM2,RASGEF1A,NTN1,MAP3K3,RASGRF1,TGIF1,PCGF5,TRIM8,NR4A1,DRAP1,SLC35C1,FXR2,ILK,RNF19B,DDX23,NIN,MMP15,DDAH1,SMTNL2,SYT7,CORO1C,C1orf21,RAB31,NXPH4,TMOD2,HS3ST3B1,PRIMA1,ITPKA,STARD13,HS6ST3 |
| 7.960e-03 | -4.83 | V$BRN2_01 | MSigDB lists | V$BRN2_01 | 228 | 47 | 17758 | 2588 |
INPPL1,TXN,ETV5,IRX4,NFAT5,ZNF385B,MECOM,CCND1,CTNNBIP1,FOXP2,MDM1,ANKS1B,CDKL5,TACC2,FLRT3,SGK3,STEAP2,DUSP10,TSPAN13,PIM1,IQGAP3,OSBPL7,PLCB2,MYT1,ETV4,DNAI1,PDGFC,TEF,SNTB2,BCL9,SAT1,VAMP3,CBL,ANLN,FOS,COL12A1,EDNRA,KLF12,FGFR2,NR4A3,SPRY4,ZMIZ1,ARF6,HOOK1,NR3C2,NDST3,TOB1 |
| 7.969e-03 | -4.83 | Ras_GEF_dom | interpro domains | IPR023578 | 30 | 10 | 18293 | 2672 |
BCAR3,RASGRF1,RALGPS2,RAPGEF2,KNDC1,SH2D3C,RASGRP3,RASGEF1A,RASGRP1,RASGRP2 |
| 7.969e-03 | -4.83 | RASGEF_cat_dom | interpro domains | IPR001895 | 30 | 10 | 18293 | 2672 |
BCAR3,RASGRF1,RALGPS2,SH2D3C,RAPGEF2,KNDC1,RASGRP3,RASGEF1A,RASGRP1,RASGRP2 |
| 7.972e-03 | -4.83 | regulation of transport | biological process | GO:0051049 | 1736 | 294 | 16441 | 2455 |
DOC2A,LAMP1,TXN,LGR4,ATP8A1,CACNA2D2,GATA3,LGI3,IL18,SYTL4,CAMK1D,BARD1,PICK1,NCS1,CALM2,STIM1,CABP1,KCNS3,DNM2,CRY2,TMEM37,PACSIN1,VPS11,ACVR1C,BNIP3L,NBPF3,PRKAR2B,SLC25A5,PNKD,RAB2B,LCP1,ABR,ENPP1,PLCG1,SLC25A4,DNM1L,MYLK,NOD2,SARAF,RNASEL,ARF6,SLC31A2,F2RL1,DDX58,SCN5A,NFKBIE,HLA-E,PRKAA1,RAB23,SLC25A27,MERTK,CALR,RAC2,RIMS3,DAPK1,SORL1,CACNA1D,MAPK7,SYTL3,NUP85,RIMS2,GCC2,KCNJ12,CALM1,ANO6,KIF20B,PRKAG2,HTT,ITPR1,OSCP1,STK39,TRPC3,NUP58,TMEM173,EHD1,DMPK,THRA,IQGAP1,PKP2,CD274,PRKACA,APC2,NOV,CDH1,SP100,RALB,DACT1,DAB2IP,PDE4D,ACSL4,TSPAN1,RAB27B,MYT1,SCN3A,PFKFB2,DMTN,VPS4B,UTRN,PRKCQ,ATP1B1,CBL,ITPR3,SNX12,FZD7,IRS2,WFS1,AXL,WWTR1,INPP4B,NRG1,RAB29,PRKAR1A,TCAF1,NKX3-1,TRAF2,SDC4,FLOT1,CBLL1,PLD2,ANO9,KCNC4,FGF19,ICAM1,WWP2,NEO1,SNTA1,OXCT1,GNB5,PTEN,KCNK5,GPC3,FAM20B,SGK3,BAX,TMBIM6,MAPK11,ERBB3,TPCN1,HCN3,RASGRF1,CASK,PIK3R1,GRIN1,VAMP3,PIM3,GPLD1,NUCB1,LDLRAP1,SYT7,NR4A3,ITGAV,GPER1,FHL1,NUP37,FZD5,EXPH5,ILDR1,ITPR2,CACNB4,PDGFB,ERP29,SLC8B1,SDC1,ZFYVE16,NKAIN3,RAB15,NUP210,CTNNB1,DPYSL2,SIVA1,PASK,ABCA2,DLG1,TRPC1,RAB20,MYRIP,RASGRP1,KCNIP3,EZR,NKAIN1,CLCN2,TRIM9,KCNMB4,RAB11FIP1,CAB39,RAP1GAP,TC2N,PRSS8,BMF,PPP1R12A,LGALS3,SERPINE2,BVES,UBASH3B,FXYD3,CALM3,FBLN1,ANO1,IL18R1,CA2,PFKL,GATA2,KCNN4,PRKCI,FXYD5,MDFIC,WNT3A,MDFI,EGFR,CDK5R1,GNAS,INSR,TMEM30A,NFKBIA,YOD1,PLD1,ATP1B3,JAK3,PROM2,DRD1,KCNAB3,SORBS1,TP53,ERBB2,P2RX7,MICALL2,BCAP31,SYTL2,PER2,IER3,REEP1,PLCG2,SMO,CDH3,TWIST1,SCN2A,F2R,HSPA2,CHP1,PPIF,SIRT1,CLCN3,BAG4,ERLEC1,AKT1,PTGER4,CD40,PTGS2,ATP1A1,EFNA5,SYT13,ABCA1,BIN1,PACSIN2,PINK1,CD63,ARHGEF7,PSMD10,HMGN3,TGFBR1,KIF5B,CARD8,ADRBK1,ADORA1,CDK16,LLGL2,BMP7,UBE2J1,SGK1,TSPAN13,CPLX1,SYK,CAMK2G,MYO5A,P2RX4,HES1,RHOA,RAB3B,SYBU,LITAF,RGCC,PPARA,USP6,MAP1B,BANK1,NETO2,E2F1,ARRB1,PKD2,SPCS3,NDFIP1,TBC1D4,PKIA,ABCG1 |
| 7.990e-03 | -4.83 | PFKM (phosphofructokinase, muscle) | protein interactions | 5213 | 54 | 16 | 16036 | 2547 |
FHL2,FBXO6,PRRC1,PKM,MCFD2,PCBP1,C4orf27,EGFR,DCP2,PTPRF,PCNA,PFKL,AURKA,YOD1,CPPED1,CTH |
| 7.996e-03 | -4.83 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDM_DN | 188 | 40 | 17758 | 2588 |
SORT1,ARHGEF3,CCDC109B,HJURP,RASA2,PBX3,KCTD12,GTF3A,ITPR2,LACTB2,CNTROB,SDC1,SLC20A1,MAGOHB,RASSF8,ATP6V0B,OXCT1,SLC35B4,FAM63A,BCL6,CCDC82,IL17RA,SLAIN2,CKAP4,EEF1D,METAP2,ADAM17,PSRC1,PLAUR,LPGAT1,STK17B,CYB5A,RHOB,ZMPSTE24,FGD6,SPCS3,NUP37,UBE2C,SERPINB1,RTN3 |
| 7.996e-03 | -4.83 | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | 188 | 40 | 17758 | 2588 |
GRN,LASP1,HECA,BMF,S100A11,LFNG,JKAMP,RPS6KA1,TSC22D3,CTSB,IL27RA,FAM78A,TMEM170B,PCBP1,CXCL16,RNF220,RGS12,WDR44,FBXO7,BRI3,PPP1CA,CTDSP2,TMBIM1,S100A6,MED22,MAP3K3,ORAI2,TACC1,SERTAD3,UBAC1,RUNX3,TNFAIP8L1,FAM73B,ICMT,ATXN7L3,SH2D3C,RAB31,ZDHHC7,SRSF9,CTDSP1 |
| 7.996e-03 | -4.83 | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDM_DN | 188 | 40 | 17758 | 2588 |
CCNI,SIGIRR,TRIM2,CCDC109B,NQO1,IBTK,CYP2J2,ESRP1,MRAS,SORBS3,CDIPT,DNER,SEPP1,ANO1,XPR1,SLC25A45,ARTN,DAPK1,USP1,AK3,HLA-C,TECR,SCN2A,CITED2,RASGRP1,ERMP1,ARHGDIB,PRRC1,RAB38,TANC1,C3orf58,ATP1A1,TIMM8A,NR1D2,WIPI1,AMMECR1,ATP6V1C1,ARF6,CTBP1,ZBTB33 |
| 7.996e-03 | -4.83 | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN | 188 | 40 | 17758 | 2588 |
SSH1,HJURP,IBTK,CDCA3,ETNK1,MMADHC,ERCC6L,PSMD10,GSTP1,MAP1LC3B,CENPN,BTG3,TGFBR3,CCNA2,PTEN,P4HB,PLK4,SGK1,RAB20,RNASEH2A,NCAM1,TRAM1,GCNT1,HES1,RHOA,TMEM43,SPA17,PYGL,GALNT7,RAD17,MCFD2,LDB2,RHEB,DNAJC10,FAM3C,RYK,GLB1,NCAPG2,CHPT1,SHROOM2 |
| 7.996e-03 | -4.83 | V$FOXD3_01 | MSigDB lists | V$FOXD3_01 | 188 | 40 | 17758 | 2588 |
FRMD4A,CHCHD7,CAST,ETV5,FLOT1,SYTL2,NEO1,IER3,KCTD15,RALGPS2,RNF128,CYR61,NPNT,CALD1,LMO4,SLC44A1,BCL6,SGK1,TWIST1,TACSTD2,DIXDC1,NTN1,CITED2,FGFR1OP2,CKAP4,CYP26B1,NR4A1,SLC39A8,UTRN,RGAG1,KDM3A,NFIX,FYN,KLF12,COL13A1,PPP1CB,PRIMA1,STARD13,CDAN1,TOB1 |
| 7.996e-03 | -4.83 | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP | 188 | 40 | 17758 | 2588 |
WASF3,ZSWIM5,ANKRD13D,IL15,FLYWCH2,CALB2,PTTG1,MIER3,NDRG2,KCTD12,CCNL1,CRABP2,KCNC4,ART5,CCDC92,NOV,RNF128,LRRN2,CYR61,NPNT,SLC16A6,FJX1,SNX16,ACOX2,DUSP1,SUN2,GCA,B3GNT7,CKAP2L,PRICKLE1,KCTD20,KIAA1109,MAGED2,PITX2,CACHD1,PLEKHH2,PELI2,OVOL1,ADIPOR1,OSR1 |
| 7.996e-03 | -4.83 | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP | 188 | 40 | 17758 | 2588 |
KLF2,ARMC7,ARL4C,FAM78A,SEPP1,SLC20A1,ICAM1,HLA-A,GNS,CEP97,FAM160A2,KLF3,CDKN1B,SGK1,C10orf54,RASGRP1,LRRC24,SUN2,ORAI2,TNIP1,SLC37A1,BNIP3L,VWA1,YES1,KCTD2,DOCK5,SESN1,PLCG1,JAK1,PPP2R5A,NR1D2,STAT6,STK38,C1orf21,TRAF3IP1,PGM2L1,FAM117A,TTC39C,TOB1,ABCG1 |
| 7.996e-03 | -4.83 | KASLER_HDAC7_TARGETS_1_UP | MSigDB lists | KASLER_HDAC7_TARGETS_1_UP | 188 | 40 | 17758 | 2588 |
TTC39B,PEX6,BVES,RPS6KA1,UBASH3B,PBX3,P2RX7,SBF1,ERP29,CHST2,PICK1,SESN3,FRYL,OSBPL3,BCL6,DUSP10,H2AFY,STEAP3,PIK3CD,TMEM37,ANKRD9,NCOA2,GM2A,TDP1,ELK3,ZC3H11A,TESK1,NR4A1,PTGER4,CLSTN1,HMG20B,TRIM35,CYFIP2,ZBTB7B,NCOA3,IDE,SEMA4D,RHOBTB2,B4GALT3,NRGN |
| 7.996e-03 | -4.83 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP | 188 | 40 | 17758 | 2588 |
SLC25A24,FAM189A2,FRMD6,RHBDL3,CCM2,GATA3,GPSM2,PHLPP1,SNN,TMCC3,LYPD5,BDH1,TUBGCP6,MTMR10,ATRNL1,SLAIN2,NTN4,PIM1,STT3B,UPF3A,SULF2,DUSP1,TUBA4A,TGIF1,RGMB,ERBB2IP,SNAPC2,SAV1,GTF2A2,RASGRP2,PRDX4,LRRC42,LDLRAP1,RBM47,TIMM8A,SLC9A6,STK39,HS3ST3B1,MAP3K5,TRPC3 |
| 7.996e-03 | -4.83 | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 188 | 40 | 17758 | 2588 |
CD99,LZTFL1,HJURP,CAST,SDC4,HABP4,ERBB2,CUL1,CYB561,IL27RA,INTS8,TRIB2,DHRS3,LTBP3,ABCD4,CORO1B,TMEM63A,CAPN2,TOP2A,ADD3,TMEM62,IL6ST,PASK,TFG,DLG3,TRAM1,CASK,MRPS33,PLEKHO1,CAPNS1,RAD17,ITPR3,SESN1,STEAP1,IARS2,PIK3C2B,RPL22,HSPB1,CBX5,DOCK9 |
| 7.996e-03 | -4.83 | GSE13306_TREG_VS_TCONV_SPLEEN_DN | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_DN | 188 | 40 | 17758 | 2588 |
CYB561,FAM78A,BAIAP3,DSE,SLC20A1,ERP29,MNS1,EXT2,SH3KBP1,LGALS3BP,SYTL2,TFAP4,OTUD1,SESN3,TGFBR3,CDH1,CYP2S1,SIVA1,SORL1,TRPC1,ALDH3A2,CTDSP2,QSOX1,PCDH1,HMGN5,SLC39A8,SEPT6,HSPA12A,NFE2L1,KIAA1109,BCL2L13,GNA11,SP4,IL1R1,AHRR,DUOX1,RCBTB2,PGM2L1,HS3ST3B1,AHR |
| 7.996e-03 | -4.83 | V$HFH4_01 | MSigDB lists | V$HFH4_01 | 188 | 40 | 17758 | 2588 |
NFKBIE,CPEB4,CHCHD7,FAM134A,TSPAN17,CYP26A1,NEO1,FOXP2,CCND1,KCTD15,ITGA3,ANKS1B,ZIC5,SLC44A1,MITF,KLF3,BCL6,H2AFY,SGK1,TWIST1,TSPAN13,CACNA1D,NTN1,CITED2,CYP26B1,TGIF1,SPATA18,HN1L,RGAG1,EBF2,GABARAPL1,COL13A1,TIMM8A,NR4A3,PPP1CB,ADAMTS14,NRG1,REEP4,CDAN1,RNF146 |
| 7.996e-03 | -4.83 | GSE360_DC_VS_MAC_DN | MSigDB lists | GSE360_DC_VS_MAC_DN | 188 | 40 | 17758 | 2588 |
CCNI,SPC25,PSME2,TSC22D3,BTN3A1,P2RX7,CRABP2,FLT3,PHF1,CARD10,GBX2,CKAP5,TYMP,ST5,RPS6KA2,KHNYN,RALB,RRBP1,ATP8B1,SLC16A5,FAM134C,DLGAP1,TIMP2,VAMP3,EMP3,RUNX3,AURKB,ILK,PRDX4,CNOT2,SCARB2,FYN,KBTBD2,SPAG7,IRF7,SSNA1,GLA,ARHGAP4,USF2,MAFF |
| 7.996e-03 | -4.83 | GSE17721_PAM3CSK4_VS_CPG_1H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_1H_BMDM_DN | 188 | 40 | 17758 | 2588 |
LZTFL1,KIF3C,TSC22D3,RASA2,DNAJB2,ETNK1,STRN4,RACGAP1,CHAC2,SPSB1,TSPAN17,ZFYVE16,FAM160A2,TMBIM1,ATG4D,PRODH,PLSCR1,TEF,FOXJ2,TMEM98,UTRN,RAB2B,FAS,FUCA1,PTGS2,BTG1,RBM47,UAP1,RND3,DNM1L,PRCP,PGRMC1,NFKBIZ,FHL1,TTC39C,NDE1,PSMC1,CBX4,ZBTB33,HS6ST3 |
| 8.001e-03 | -4.83 | negative regulation of protein localization to nucleus | biological process | GO:1900181 | 67 | 18 | 16441 | 2455 |
NFKBIE,THRA,LITAF,RAB23,PSMD10,APC2,NOV,CABP1,BMP7,WWTR1,NFKBIA,DAB2IP,PKD2,MDFIC,MAPK7,PKIA,CHP1,MDFI |
| 8.001e-03 | -4.83 | regulation of Notch signaling pathway | biological process | GO:0008593 | 67 | 18 | 16441 | 2455 |
HES1,TSPAN15,LFNG,SLC35C1,JAG2,TSPAN17,CD46,NOV,PDCD10,GATA2,LLGL2,IL6ST,BMP7,NFKBIA,NOD2,BCL6,EGFL7,TSPAN33 |
| 8.016e-03 | -4.83 | LIN7C (lin-7 homolog C (C. elegans)) | protein interactions | 55327 | 32 | 11 | 16036 | 2547 |
AMOTL2,KCNJ12,CASK,DLG1,MPP2,MPP5,APBA1,PXDC1,ABCA1,ABLIM2,ARHGEF26 |
| 8.021e-03 | -4.83 | RASGEF_CAT | prosite domains | PS50009 | 29 | 10 | 11866 | 1802 |
BCAR3,RASGRF1,RALGPS2,SH2D3C,RAPGEF2,KNDC1,RASGRP3,RASGEF1A,RASGRP1,RASGRP2 |
| 8.029e-03 | -4.82 | regulation of plasma membrane organization | biological process | GO:1903729 | 72 | 19 | 16441 | 2455 |
LZTFL1,SORBS1,AKT1,PIK3R1,EZR,PLS1,BCL2L1,ARHGEF16,STX3,KIF5B,LDLRAP1,ITGA3,PPP2R5A,DNM2,PRKCI,DLG1,GPER1,ARF6,TMBIM1 |
| 8.029e-03 | -4.82 | centrosome organization | biological process | GO:0051297 | 72 | 19 | 16441 | 2455 |
PLK1,PPP1R12A,UXT,CNTROB,STIL,KIF11,CDK1,SSX2IP,CKAP5,CTNNB1,CENPJ,TUBGCP6,PLK4,NEK2,AURKA,PKD2,NDE1,SGOL1,FBXW5 |
| 8.042e-03 | -4.82 | myelin assembly | biological process | GO:0032288 | 17 | 7 | 16441 | 2455 |
CNTNAP1,MPP5,ERCC2,UGT8,ILK,PIKFYVE,CD9 |
| 8.042e-03 | -4.82 | negative regulation of smooth muscle contraction | biological process | GO:0045986 | 17 | 7 | 16441 | 2455 |
DOCK4,CALCRL,PTGS2,SOD1,ADORA1,DOCK5,PRKG1 |
| 8.042e-03 | -4.82 | interferon-gamma production | biological process | GO:0032609 | 17 | 7 | 16441 | 2455 |
BTN3A1,BTN3A2,GATA3,IL18,RNF19B,F2RL1,TXK |
| 8.044e-03 | -4.82 | DELASERNA_MYOD_TARGETS_UP | MSigDB lists | DELASERNA_MYOD_TARGETS_UP | 84 | 21 | 17758 | 2588 |
BIN1,PRSS23,CD82,LRP4,HDAC11,PLEKHO1,SCRIB,PRKAR2B,STK17B,RHOB,TMCC3,RB1,ATP1A1,PDLIM3,ANKS1B,BCL6,GYS1,DYSF,KLF5,ANXA11,DMPK |
| 8.066e-03 | -4.82 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | molecular function | GO:0016620 | 34 | 11 | 16491 | 2452 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH1A3,ALDH7A1,FAR2,FAR1,PDHX,ALDH3A2,DLAT |
| 8.066e-03 | -4.82 | galactosyltransferase activity | molecular function | GO:0008378 | 34 | 11 | 16491 | 2452 |
B3GALT6,B3GALNT1,B3GNT7,UGT8,B3GNT2,A4GALT,C1GALT1C1,B4GALT4,PLOD3,B3GALNT2,B4GALT3 |
| 8.080e-03 | -4.82 | G0 and Early G1 | REACTOME pathways | R-HSA-1538133 | 25 | 9 | 8202 | 1235 |
TOP2A,CCNE2,PCNA,CCNA2,RBL1,E2F1,MYBL2,HDAC1,CDK1 |
| 8.088e-03 | -4.82 | negative regulation of defense response | biological process | GO:0031348 | 140 | 32 | 16441 | 2455 |
NLRX1,HLA-E,SERPINB9,TAP1,GATA3,ETS1,GSTP1,HLA-A,IER3,NOV,ADORA1,TSPAN6,DUSP10,IFIT1,MAPK7,PSMB4,PBK,MICB,ITCH,SHARPIN,PPARA,PTGER4,CALCRL,ABR,SOCS3,HLA-B,NMI,TRAF3IP1,NLRC5,NOD2,GPER1,NDFIP1 |
| 8.090e-03 | -4.82 | negative regulation of leukocyte apoptotic process | biological process | GO:2000107 | 43 | 13 | 16441 | 2455 |
IRS2,TSC22D3,AXL,BCL6,NOD2,IRF7,PRKCQ,AURKB,SLC39A10,RAG1,JAK3,MERTK,BCL10 |
| 8.090e-03 | -4.82 | regulation of release of cytochrome c from mitochondria | biological process | GO:0090199 | 43 | 13 | 16441 | 2455 |
PPIF,PINK1,BMF,AKT1,DNM1L,PLAUR,BIK,TP53,BAX,PSMD10,GPER1,BCL2L1,LMNA |
| 8.091e-03 | -4.82 | response to steroid hormone | biological process | GO:0048545 | 402 | 78 | 16441 | 2455 |
CASP3,TRIM24,NQO1,THRA,GATA3,ERBB2,PDGFB,SDC1,CALM2,CCND1,CCNA2,CTNNB1,CTGF,FOSB,ABCA2,CLDN4,CDKN1B,GOT1,ASH2L,ARNT2,NR2C1,THRB,CITED4,PTPRU,CASP9,IDH1,SOCS3,MDK,PTGS2,ATP1A1,MAP2,AREG,NR3C2,NR2C2,GRN,ANXA3,NKX3-1,SERPINB9,CALM3,ETS1,CALR,TFAP4,SPP1,CA2,PTEN,BMP7,CST3,BAX,IGFBP2,KLF9,CITED2,DUSP1,PAQR7,RHOA,NR3C1,NR4A1,CALM1,PPARA,ELK1,FOS,EGFR,FAS,FECH,MMP15,RGS9,NCOA3,TIMP3,NR1D2,CTSV,NR4A3,AURKA,NR4A2,HOXB13,GPER1,ARSB,RARG,FOXA1,DRD1 |
| 8.095e-03 | -4.82 | ACACA (acetyl-CoA carboxylase alpha) | protein interactions | 31 | 68 | 19 | 16036 | 2547 |
SIRT1,PRKAA2,DCAF6,INPPL1,SUZ12,RPS6KA1,UBASH3B,PRKAA1,ERCC6L,FBXO6,CBL,ILK,VCP,EGFR,KIF5B,ADRBK1,ARRB1,IFIT1,PHKG2 |
| 8.095e-03 | -4.82 | HLA-B (major histocompatibility complex, class I, B) | protein interactions | 3106 | 68 | 19 | 16036 | 2547 |
NEK4,HLA-E,ARFGEF1,EZR,FAM91A1,HLA-A,VCP,PLS3,HLA-B,CD8A,PSMD1,WDR11,HTT,CSF1,STAT1,ERAP1,AHCY,HLA-C,ARHGEF4 |
| 8.121e-03 | -4.81 | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | 160 | 35 | 17758 | 2588 |
PARP12,PSME2,HLA-E,HLA-F,HERC5,HERC6,SBF1,STIL,LGALS3BP,HLA-A,CALR,TYMP,TAF1B,TRANK1,USP1,IFIT1,HLA-C,OAS3,CKS2,REC8,MX1,HMMR,MLEC,IFITM3,USP18,IFIT3,PDHX,HLA-B,NCOA3,C19orf66,NMI,STAT1,IRF7,IFIH1,IFI6 |
| 8.129e-03 | -4.81 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | 211 | 44 | 17758 | 2588 |
CCNC,GALK1,DYRK3,SERPINE2,ST14,DDIT4L,NDRG1,TAP1,JAG2,KBTBD11,PHLDA1,COX7A2,IER3,TFAP4,RB1,CPNE2,CTGF,PFKL,SIVA1,TMEM143,DAPK1,EGLN3,ZNF365,ETV4,KANK3,RNF169,CLCN3,PGM1,ARAP2,PSRC1,PQLC3,IFITM3,MAPKAPK3,RNF165,BNIP3L,PLOD2,WIPI1,PTK7,P4HA2,CGREF1,SP6,CD81,DEF6,EGLN1 |
| 8.139e-03 | -4.81 | SAGIV_CD24_TARGETS_DN | MSigDB lists | SAGIV_CD24_TARGETS_DN | 44 | 13 | 17758 | 2588 |
APOBEC3B,TRIM8,CABP1,N4BP3,BIK,EMP3,GDF15,CTTN,GEM,PDGFB,ULBP2,DUSP5,ICAM1 |
| 8.139e-03 | -4.81 | KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION | MSigDB lists | KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION | 44 | 13 | 17758 | 2588 |
PCCB,ALDH2,OXCT1,ALDH6A1,ACADSB,AOX1,MCCC1,ALDH7A1,HMGCL,ACADM,ACAD8,ALDH3A2,MCCC2 |
| 8.139e-03 | -4.81 | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | MSigDB lists | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | 44 | 13 | 17758 | 2588 |
CENPA,DLGAP5,LGALS3,P4HB,PSME2,SAT1,KPNA2,HMGA1,CCNB1,CTSD,PSMC1,GM2A,MELK |
| 8.139e-03 | -4.81 | ZHAN_MULTIPLE_MYELOMA_MF_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MF_UP | 44 | 13 | 17758 | 2588 |
CD109,DOCK4,SPP1,TRIM47,TYMP,SHMT1,MCTP1,CDH1,NUAK1,ABHD12,DPYSL2,TMEM37,ATP13A2 |
| 8.139e-03 | -4.81 | CHANDRAN_METASTASIS_TOP50_DN | MSigDB lists | CHANDRAN_METASTASIS_TOP50_DN | 44 | 13 | 17758 | 2588 |
MAGED2,B3GALNT1,MRC2,NR4A1,STAT6,AIM1,EFHD2,CHMP4B,POMT1,ETHE1,FOS,KCTD3,ANXA11 |
| 8.146e-03 | -4.81 | growth | biological process | GO:0040007 | 408 | 79 | 16441 | 2455 |
EMX1,GRHL2,ADD1,IQGAP1,WDTC1,TP53,GATA3,PLAC1,BCL2L1,CCNB1,PDGFB,STIL,NOV,TGFBR3,SMO,PDE4D,TFAP2C,KLK6,PRKCQ,ERBB2IP,ICMT,ALCAM,GINS4,ULK2,FZD7,AREG,PTK7,SLC9A6,WWTR1,EFNA5,APBA2,COBL,PRKAR1A,KLF2,CDKN1C,TMTC3,SOX9,LRP4,CCM2,NOTCH2,TEC,APBA1,SEPP1,NRP2,BMP2,PTEN,BMP7,FLRT3,ADAM15,BRAT1,ERCC2,WNT3A,SLC12A2,SPRY2,SOCS5,EPB41L5,WNT10B,FMN1,SALL4,BCL9,ASPM,RC3H2,EMP3,NUBP1,C3orf58,MAP1B,GNAS,NCOA3,TIMP3,FGFR2,CSF1,AURKA,ITGAV,GDF11,ZMIZ1,NCAPG2,SEMA3A,CCNB2,RARG |
| 8.160e-03 | -4.81 | DAZARD_RESPONSE_TO_UV_SCC_UP | MSigDB lists | DAZARD_RESPONSE_TO_UV_SCC_UP | 116 | 27 | 17758 | 2588 |
LAMP2,CCNC,NEK4,ANXA3,RECQL,NF2,CDKN1C,PLSCR1,SH3BGRL,TSC22D3,CCBL2,IL13RA1,ARHGDIB,FOS,CDK1,CYB5A,SCARB2,PTGS2,PRDX3,RALB,TACSTD2,ALDH7A1,ACADM,CITED2,PDIA6,TOB1,PRKAR1A |
| 8.183e-03 | -4.81 | innate immune response activating cell surface receptor signaling pathway | biological process | GO:0002220 | 124 | 29 | 16441 | 2455 |
PSMB4,TAB3,PSME2,CALM1,PSMD7,CALM3,PSMD10,CUL1,PSME1,ITPR2,ITPR3,PRKACA,PSMA4,BCL10,CALM2,PSMD1,FYN,PSMD3,PSMC2,NFKBIA,ITPR1,PAK2,PLCG2,UBE2D2,MAP3K7,NFKB2,SYK,PSMC1,PSMA5 |
| 8.217e-03 | -4.80 | MARTINEZ_RB1_AND_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_DN | 558 | 102 | 17758 | 2588 |
LTBP1,TRIM2,KLK10,PAX6,FAM92A1,ST14,CRYM,THRA,DNAJC3,RHBDL3,FHDC1,IRX4,PKP2,COL18A1,CCNL1,DDR1,SLC9A3R2,MAGOHB,CCND1,APLP2,GRHL1,SIVA1,FRYL,ZFP36,ALDH1A3,SLC44A1,SMO,ABCA2,CDH3,RPN2,ECE1,MYH14,TECR,ETHE1,SCARA3,PTPRE,PLK1,CLCN3,MBP,COL6A2,CENPA,CXXC5,CELSR2,CAPN6,USP18,SNTB2,PANK1,KIF1C,GLO1,ITPR3,FZD7,OVOL1,AGFG2,TMOD2,UNC5B,TC2N,CD99,LASP1,COL9A3,PCOLCE,CDKN1C,HJURP,ESRP1,SOX9,RAB6A,GSTP1,TNFRSF19,EFNB1,FZD6,NEO1,TMCC3,CALR,CTNNBIP1,DOPEY2,CALD1,ATP5H,IGFBP2,NTN1,SLC45A3,FAM134C,EPHX1,IGDCC4,NFE2L3,SHMT1,CTNNAL1,GCLC,ELOVL3,MYBL2,NFIB,EGFR,FRMD4B,PTPRF,TIMP3,CTNS,FA2H,PVRL2,PLOD2,CLIP4,LTBP2,MAP3K5,RARG,SNX30 |
| 8.223e-03 | -4.80 | protein localization to cell periphery | biological process | GO:1990778 | 151 | 34 | 16441 | 2455 |
TSPAN15,FLOT1,PKP2,F11R,MPP5,EMP2,TSPAN17,RAB15,ANK1,CDH1,DLG1,ZDHHC23,PLEKHF1,PACSIN1,FLOT2,TSPAN33,MYO5A,TMED2,GCC2,RAB3B,BAG4,KCNIP3,CRB3,RAPGEF2,VAMP3,EZR,KIF13A,ARFRP1,ATP1B1,BBS2,NUBP1,OPTN,RAB31,ATP1B3 |
| 8.228e-03 | -4.80 | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | 194 | 41 | 17758 | 2588 |
GRN,LGALS3,S100A11,RPS6KA1,CTSB,HEXB,ASAH1,EFHD2,KCTD12,NOTCH2,GNS,VASP,MGAT1,SLC16A6,CAPG,SGK1,H2AFY,CTSD,PTPRE,CKAP4,GCA,TRIM8,TIMP2,MAPKAPK3,S100A4,VAMP3,ILK,ABR,ATP1A1,SERPINA1,RBM47,SEMA4D,RAB31,PNPLA6,NOD2,SERPINB6,PLXND1,ZMIZ1,SLC27A3,SLC31A2,RTN3 |
| 8.228e-03 | -4.80 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN | 194 | 41 | 17758 | 2588 |
GALK1,GCLM,FAF2,PSME2,SDC4,TAP1,ETNK1,RAB23,RACGAP1,FANCI,NAPG,RBM23,PCNA,PPP1R10,OSBPL3,PSMC2,BAX,MANF,TFG,MINPP1,FAR2,TMED2,TBC1D10B,FAH,GFPT1,DDB2,SEC61B,ZWINT,FURIN,ADRBK2,PRDX4,GALNT3,NCOA3,PRDX3,FAM3C,ITPR1,CANT1,CSTF2,ZBTB6,ISOC1,SRSF9 |
| 8.260e-03 | -4.80 | Gastrin-CREB signalling pathway via PKC and MAPK | REACTOME pathways | R-HSA-881907 | 424 | 82 | 8202 | 1235 |
SPRED1,PSME2,RPS6KA1,IQGAP1,DGKA,ERBB2,NRG2,RASGRP3,PSME1,ITPR2,PDGFB,SPTB,GNB2,GRM5,CALM2,PDGFA,PSMD1,RPS6KA2,SHC3,PSMC2,PIK3CA,DUSP10,DAB2IP,RASGEF1A,F2R,RASGRP1,FRS3,PRKCQ,DUSP4,ITPR3,EDNRA,IRS2,FYN,PPP2R5A,JAK1,ABHD12,PSMD3,MAP3K11,NRG1,SPTBN5,F2RL1,PSMC1,PPP2R5D,RASA2,DGKQ,PSMD7,CALM3,PSMD10,FGF19,DUSP5,ITGA2B,GNB5,ADRBK1,ERBB3,NCAM1,MAPK7,PLCB2,DGKG,PSMA5,CAMK2G,DUSP1,RASGRF1,PSMB4,RAPGEF2,PIK3R1,CALM1,GRIN1,PSMA4,GNA11,RASA1,EGFR,DGKE,RASGRP2,DGKH,FGFR2,ITPR1,FGF18,ARRB1,GRIN2D,TRPC3,JAK3,RPS6KA3 |
| 8.261e-03 | -4.80 | MITOCARRIER | prints domains | PR00926 | 27 | 9 | 4759 | 661 |
SLC25A48,SLC25A45,SLC25A24,SLC25A4,SLC25A13,SLC25A40,SLC25A5,SLC25A43,SLC25A36 |
| 8.267e-03 | -4.80 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | MSigDB lists | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | 79 | 20 | 17758 | 2588 |
CASP3,RASGRF1,ADAM17,ARHGEF3,RHOA,RIPK2,ARHGEF11,ARHGEF16,ABR,IRAK1,NGFRAP1,NFKBIA,PRKCI,HDAC1,ARHGAP4,TIAM1,ARHGEF9,NGEF,FGD1,ARHGEF4 |
| 8.289e-03 | -4.79 | cellular response to oxidative stress | biological process | GO:0034599 | 173 | 38 | 16441 | 2455 |
KLF2,SLC25A24,PINK1,NQO1,EPAS1,TRAF2,ETV5,PRKAA1,SOD2,TP53,HDAC6,ETS1,PDCD10,CST3,DNM2,AKR1B1,MAPK7,CYP1B1,SIRT1,PPIF,PRODH,SOD1,OXR1,NFE2L1,SLC11A2,PRKRA,FOS,RHOB,ALDH3B1,PRDX3,DHRS2,OSER1,PKD2,NR4A2,MAP3K5,ARNT,CPEB2,MELK |
| 8.323e-03 | -4.79 | odontogenesis | biological process | GO:0042476 | 103 | 25 | 16441 | 2455 |
SCN5A,RUNX2,NF2,ITGA6,LRP4,PPARA,JAG2,OSR2,SDC1,PITX2,BMP2,CA2,CTNNB1,STIM1,FGFR2,FAM20C,TBX1,BMP7,SMO,BAX,CNNM4,HDAC1,TWIST1,OSR1,MYO5A |
| 8.328e-03 | -4.79 | T cell homeostasis | biological process | GO:0043029 | 34 | 11 | 16441 | 2455 |
CASP3,AKT1,SIVA1,RC3H2,BAX,P2RX7,PPP2R3C,RAG1,CCNB2,JAK3,FAS |
| 8.328e-03 | -4.79 | response to amphetamine | biological process | GO:0001975 | 34 | 11 | 16441 | 2455 |
CALM2,SOD1,DPYSL2,CALM1,GNAL,GRIN1,CALM3,NR4A2,ICAM1,HDAC9,DRD1 |
| 8.369e-03 | -4.78 | SH3_2 | pfam domains | PF07653 | 57 | 16 | 16629 | 2504 |
DOCK4,SORBS1,CASK,MACC1,ARHGEF7,SH3D19,MPP1,RUSC2,MPP5,SH3RF2,SH3D21,TJP3,ARHGEF37,MCF2L,MPP2,SH3BP4 |
| 8.376e-03 | -4.78 | PEA15 (phosphoprotein enriched in astrocytes 15) | protein interactions | 8682 | 20 | 8 | 16036 | 2547 |
LGR4,AKT1,PLD2,PLD1,L1CAM,CAMK2G,RPS6KA3,ABCD4 |
| 8.376e-03 | -4.78 | DIAPH3 (diaphanous-related formin 3) | protein interactions | 81624 | 20 | 8 | 16036 | 2547 |
SIRT1,CENPA,RHOA,HDAC6,CCNB1,PNKD,CCNB2,VCP |
| 8.376e-03 | -4.78 | ANKRD44 (ankyrin repeat domain 44) | protein interactions | 91526 | 20 | 8 | 16036 | 2547 |
PLK1,CDKN2C,PLK2,NOTCH2,NOTCH3,PPP6R1,WWP2,USP6 |
| 8.376e-03 | -4.78 | GRIK2 (glutamate receptor, ionotropic, kainate 2) | protein interactions | 2898 | 20 | 8 | 16036 | 2547 |
CASK,CTNNB1,GRIK2,PRKAA1,DLG1,CTNND1,DLG3,PICK1 |
| 8.382e-03 | -4.78 | CAMK1 (calcium/calmodulin-dependent protein kinase I) | protein interactions | 8536 | 28 | 10 | 16036 | 2547 |
CCND1,PPME1,CAMKK1,CALM1,CDKN1B,CAMK1D,PNKD,HSPB1,HDAC9,CDK14 |
| 8.435e-03 | -4.78 | HS-GAG degradation | REACTOME pathways | R-HSA-2024096 | 21 | 8 | 8202 | 1235 |
AGRN,HPSE,HSPG2,GUSB,GPC3,SDC4,GLB1,SDC1 |
| 8.435e-03 | -4.78 | ERK/MAPK targets | REACTOME pathways | R-HSA-198753 | 21 | 8 | 8202 | 1235 |
RPS6KA2,RPS6KA1,MAPK11,MAPK7,ELK1,DUSP4,PPP2R5D,RPS6KA3 |
| 8.440e-03 | -4.77 | NON_MEMBRANE_BOUND_ORGANELLE | MSigDB lists | NON_MEMBRANE_BOUND_ORGANELLE | 614 | 111 | 17758 | 2588 |
MYL9,KIF3C,SORBS1,NF2,DLGAP5,TUBB4B,MRPS15,IQGAP1,KLC2,NDC80,TP53,KIF2C,CNTROB,MORF4L2,HDAC6,SPTB,APPBP2,NPM2,PCNA,RGS12,CDH1,CTNNB1,CNTRL,CABP1,CAPG,BCL6,ABCA2,TUBG1,KIF22,ESPN,EPB41L4B,CTTN,NEB,ATG4D,PLK1,DOCK4,CDKN2AIP,LOC81691,PCGF5,TAF5,CENPA,MARK1,UXT,CDC20,UTRN,EZR,MRPS35,ARHGDIB,MRPS18A,PIF1,ANLN,MRPS36,MYOM1,CDK1,DAG1,NIN,MAP2,SHROOM3,CORO1C,MAP3K11,MRPS28,HSPB1,BIN1,LASP1,BMF,FARP1,USH1C,KIF23,DNAJB9,SAC3D1,ATG4A,CKAP5,TOP2A,KIF5B,RB1,VASP,CALD1,TUBGCP6,TBCD,RRBP1,PRC1,DAPK1,NEK2,H2AFY,BUB1,KNTC1,CLIP2,SMC4,DNAI1,CASK,ZWINT,KIF20B,AIF1L,KIF11,RANBP9,ABLIM2,MAP1B,KLHL2,TSC1,CDCA5,FGF18,AURKA,PKD2,CENPE,ARPC2,CEP41,NDE1,CCNB2,CBX5,SHROOM2,ESPL1 |
| 8.440e-03 | -4.77 | INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE | MSigDB lists | INTRACELLULAR_NON_MEMBRANE_BOUND_ORGANELLE | 614 | 111 | 17758 | 2588 |
MYL9,KIF3C,SORBS1,DLGAP5,NF2,TUBB4B,MRPS15,IQGAP1,KLC2,NDC80,TP53,KIF2C,CNTROB,MORF4L2,HDAC6,SPTB,APPBP2,NPM2,PCNA,RGS12,CTNNB1,CDH1,CNTRL,CABP1,CAPG,ABCA2,BCL6,TUBG1,ESPN,KIF22,CTTN,EPB41L4B,NEB,ATG4D,PLK1,DOCK4,CDKN2AIP,LOC81691,PCGF5,TAF5,MARK1,CENPA,UXT,CDC20,UTRN,EZR,ARHGDIB,MRPS35,MRPS18A,PIF1,ANLN,MRPS36,MYOM1,CDK1,DAG1,NIN,MAP2,SHROOM3,CORO1C,MAP3K11,MRPS28,HSPB1,BIN1,LASP1,BMF,FARP1,USH1C,KIF23,DNAJB9,SAC3D1,CKAP5,ATG4A,TOP2A,KIF5B,RB1,VASP,CALD1,TBCD,TUBGCP6,RRBP1,DAPK1,NEK2,PRC1,H2AFY,BUB1,KNTC1,CLIP2,SMC4,DNAI1,ZWINT,CASK,KIF20B,AIF1L,KIF11,RANBP9,ABLIM2,MAP1B,KLHL2,TSC1,FGF18,CDCA5,AURKA,PKD2,CENPE,ARPC2,CEP41,NDE1,SHROOM2,CCNB2,CBX5,ESPL1 |
| 8.447e-03 | -4.77 | PAL_PRMT5_TARGETS_UP | MSigDB lists | PAL_PRMT5_TARGETS_UP | 200 | 42 | 17758 | 2588 |
CD99,GCAT,ABCG2,KIF23,CALM3,RACGAP1,INTS8,PSIP1,TSEN34,CALM2,IRAK1,CAPG,CKS1B,AHCY,NCAM1,LOXL1,SLC35A1,NUP85,CKS2,CYP1B1,COL6A2,KIF20A,GUSB,FIGNL1,CALM1,CDC20,EMP3,AURKB,H2AFV,SLC25A5,KIF11,CDC25C,NFIB,RASA1,PRIM1,RBL1,PRKCDBP,PKD2,KPNA2,NDE1,CCNB2,CTBP1 |
| 8.462e-03 | -4.77 | soft_tissue-striated_muscle-rhabdoid_tumour | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdoid_tumour | 172 | 37 | 17775 | 2585 |
NF2,MACC1,ARHGEF7,RET,TP53,ERBB2,NRG2,FLT3,EPS8L2,RB1,SS18,MUC16,CTNNB1,CDH1,PTEN,MSH2,SMO,PIK3CA,MYT1,MSH6,AKT1,PIK3R1,OGDHL,CCBL2,EGFR,IRX3,GNAS,DHDH,CCDC6,FGFR2,ITGA7,ZMYND19,ZFP30,CGREF1,DHTKD1,STARD13,JAK3 |
| 8.462e-03 | -4.77 | rhabdoid_tumour | COSMIC cancer mutations | rhabdoid_tumour | 172 | 37 | 17775 | 2585 |
NF2,MACC1,ARHGEF7,RET,TP53,ERBB2,NRG2,FLT3,EPS8L2,RB1,SS18,MUC16,CTNNB1,CDH1,PTEN,MSH2,SMO,PIK3CA,MYT1,MSH6,AKT1,PIK3R1,OGDHL,CCBL2,EGFR,IRX3,GNAS,DHDH,CCDC6,FGFR2,ITGA7,ZMYND19,ZFP30,CGREF1,DHTKD1,STARD13,JAK3 |
| 8.464e-03 | -4.77 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | 49 | 14 | 17758 | 2588 |
IL1R1,PTGS2,FGFR2,ZFP36,COL6A1,OSMR,LTBP2,LOXL1,DDR1,FOS,SLC12A2,CRTAP,FAS,CYP1B1 |
| 8.464e-03 | -4.77 | PRAMOONJAGO_SOX4_TARGETS_DN | MSigDB lists | PRAMOONJAGO_SOX4_TARGETS_DN | 49 | 14 | 17758 | 2588 |
LAMP1,BIN1,MLEC,KIF20A,DLGAP5,CTSC,CALD1,ADAM15,CCNB1,TMEM14A,PTGES,TMED2,MCCC2,ACOT7 |
| 8.464e-03 | -4.77 | PROTEIN_PROCESSING | MSigDB lists | PROTEIN_PROCESSING | 49 | 14 | 17758 | 2588 |
MAP3K3,TNK1,INSR,IGF1R,AKT1,CDKL5,PAK2,FURIN,KIAA1804,MAP3K11,MAP3K9,EIF2AK1,METAP2,PCSK5 |
| 8.464e-03 | -4.77 | WONG_PROTEASOME_GENE_MODULE | MSigDB lists | WONG_PROTEASOME_GENE_MODULE | 49 | 14 | 17758 | 2588 |
PSMD1,UBE2Q2,PSMB4,UBE2T,USP18,PSMD3,CDC20,UBE2D2,PSMD10,USP1,PSME1,UBE2C,PSMA4,PSMA5 |
| 8.464e-03 | -4.77 | BECKER_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | BECKER_TAMOXIFEN_RESISTANCE_DN | 49 | 14 | 17758 | 2588 |
CCND1,IL1R1,ADAM17,IGF1R,AREG,AGPS,TSPAN6,AIM1,GATA3,TIAM1,LBR,NFIB,PKIA,COX7A2 |
| 8.475e-03 | -4.77 | Epstein-Barr virus infection | KEGG pathways | ko05169 | 199 | 44 | 6908 | 1076 |
DDX58,NFKBIE,HLA-E,HLA-F,TRAF2,TP53,PSMD7,PRKACA,ICAM1,HLA-A,RB1,PSMD1,CCNA2,IRAK1,PLCG2,PSMC2,PIK3CA,CDKN1B,MAPK11,PIK3CD,HLA-C,MAP3K7,NFKB2,IL10RB,HSPA2,SYK,AKT1,PIK3R1,CR2,EIF2AK1,CD40,CDK1,HLA-B,PLCG1,JAK1,PSMD3,NFKBIA,HDAC1,MAPK13,TRAF5,HSPB1,JAK3,PSMC1,MAPK12 |
| 8.475e-03 | -4.77 | Epstein-Barr virus infection | KEGG pathways | hsa05169 | 199 | 44 | 6908 | 1076 |
DDX58,NFKBIE,HLA-E,HLA-F,TRAF2,TP53,PSMD7,PRKACA,ICAM1,HLA-A,RB1,PSMD1,CCNA2,IRAK1,PLCG2,PSMC2,PIK3CA,CDKN1B,MAPK11,PIK3CD,HLA-C,MAP3K7,NFKB2,IL10RB,HSPA2,SYK,AKT1,PIK3R1,CR2,EIF2AK1,CD40,CDK1,HLA-B,PLCG1,JAK1,PSMD3,NFKBIA,HDAC1,MAPK13,TRAF5,HSPB1,JAK3,PSMC1,MAPK12 |
| 8.477e-03 | -4.77 | transport vesicle | cellular component | GO:0030133 | 193 | 41 | 17570 | 2579 |
SORT1,SLC2A4,HLA-E,HLA-F,CTSZ,TGOLN2,RAB6A,SYTL4,ERP29,HLA-A,SYTL2,CTSC,CDK16,LMAN2L,STEAP2,HLA-C,LMAN1,RAB27B,MYRIP,CPE,SYTL3,TMED2,CHP1,CLCN3,SEC23A,SNTB2,FURIN,COL7A1,MCFD2,CRISPLD2,DPYSL3,GNAS,HLA-B,AP1AR,LDLRAP1,SERPINA1,AREG,TMEM30A,SYT13,NRGN,ARFGEF3 |
| 8.493e-03 | -4.77 | FORTSCHEGGER_PHF8_TARGETS_UP | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_UP | 252 | 51 | 17758 | 2588 |
LZTFL1,NQO1,SUZ12,XIAP,GPR180,JAG2,DHRS3,MESDC2,SGPL1,BMP2,CTGF,IGF1R,CTSC,SLC16A6,MCF2L,XYLT2,LMO4,STEAP3,WWP1,TSPAN13,KLF9,ECE1,PDE4D,CITED2,TPCN1,MGAT5,C9orf9,NEK4,PDGFC,NR4A1,GCLC,SPA17,NKAIN1,YES1,PDHX,FZD7,CMTM7,DDAH1,PTPRJ,INSR,MAP2,CCDC6,ITPR1,PIAS2,OSCP1,EFNA1,RELL1,FZD5,TBC1D4,CBX5,DCBLD1 |
| 8.500e-03 | -4.77 | HAMAI_APOPTOSIS_VIA_TRAIL_DN | MSigDB lists | HAMAI_APOPTOSIS_VIA_TRAIL_DN | 183 | 39 | 17758 | 2588 |
KLF2,ARAP3,RPS6KA1,ERBB2,BLCAP,GDF15,ISYNA1,FBLN1,ICAM1,H1FX,SAC3D1,SH3D21,TYMP,VASP,SH3BP1,MAGEE1,COL6A1,FXYD5,STEAP3,TAGLN2,SLC16A5,PLAUR,GRIN1,KLK6,F12,SNAPC2,TP53I3,FOXD2,MDK,PTPRF,SLCO4A1,TIMP3,DHRS2,MAOA,ARRB1,EFNA1,FZD5,SERPINB1,DEF6 |
| 8.500e-03 | -4.77 | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | 183 | 39 | 17758 | 2588 |
PLA2G4A,TTC39B,ALDH6A1,EPAS1,ATP8A1,UBASH3B,PYROXD2,BLVRB,ABCG2,FAM198B,MGST2,GALM,LMNA,ASPHD2,PLS3,GRHL1,ATP13A3,FXYD5,IL17RA,AHCY,NAGA,IL1RAP,CYP1B1,ERMP1,TACC1,GCLC,S100A4,ARHGDIB,ATP1B1,ESYT1,ARHGAP24,TSC1,HTT,RIN3,DTX4,NFKBIZ,CTNND1,SPCS3,CBX7 |
| 8.500e-03 | -4.77 | GSE3982_BASOPHIL_VS_TH1_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH1_UP | 183 | 39 | 17758 | 2588 |
MAN2B2,MTM1,SLC2A4,SORBS1,FAF2,NDRG1,OSGIN2,C6orf106,PBX3,DSE,ARHGEF40,MAP1LC3B,MXD1,TRANK1,LMAN2L,FAM13B,BCL6,CD9,KLF9,TRAM1,CTDSP2,DUSP1,PDGFC,VPS11,RHOA,MBP,LGALS8,S100A4,MGAM,ARHGDIB,PCTP,ATP10D,SOX13,SWAP70,PPP2R5A,HOXA9,SLC4A3,RTN3,PCSK5 |
| 8.546e-03 | -4.76 | TDGF1 (teratocarcinoma-derived growth factor 1) | protein interactions | 6997 | 24 | 9 | 16036 | 2547 |
GID8,RMND5A,ACVR1C,ZMYND19,LRIF1,FBLN1,RANBP9,AIP,WBP5 |
| 8.546e-03 | -4.76 | KCNA4 (potassium channel, voltage gated shaker related subfamily A, member 4) | protein interactions | 3739 | 24 | 9 | 16036 | 2547 |
DLGAP1,SNTA1,SIRT1,FYN,CASK,SAT1,DLG1,ERBB2IP,DLG3 |
| 8.546e-03 | -4.76 | ERO1A (endoplasmic reticulum oxidoreductase alpha) | protein interactions | 30001 | 24 | 9 | 16036 | 2547 |
P4HB,PELI2,PPME1,ERO1A,PDIA3,ERP44,FBXO6,APPBP2,PDIA4 |
| 8.550e-03 | -4.76 | MyD88 cascade initiated on plasma membrane | REACTOME pathways | R-HSA-975871 | 82 | 21 | 8202 | 1235 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 8.550e-03 | -4.76 | p75 NTR receptor-mediated signalling | REACTOME pathways | R-HSA-193704 | 82 | 21 | 8202 | 1235 |
CASP3,ADAM17,ARHGEF3,RHOA,RIPK2,ARHGEF11,ARHGEF7,ARHGEF16,ABR,IRAK1,NGFRAP1,MCF2L,NFKBIA,PRKCI,HDAC1,ARHGAP4,TIAM1,ARHGEF9,ARHGEF4,NGEF,FGD1 |
| 8.550e-03 | -4.76 | Toll Like Receptor 5 (TLR5) Cascade | REACTOME pathways | R-HSA-168176 | 82 | 21 | 8202 | 1235 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 8.550e-03 | -4.76 | Toll Like Receptor 10 (TLR10) Cascade | REACTOME pathways | R-HSA-168142 | 82 | 21 | 8202 | 1235 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 8.555e-03 | -4.76 | myelin sheath | cellular component | GO:0043209 | 165 | 36 | 17570 | 2579 |
FAM213B,ENO2,TUBB4B,NDRG1,PDIA3,ERBB2,MPP5,SEPT4,GNB2,NAPG,CA2,GNB5,PTEN,DPYSL2,DLG1,PRKCI,AKR1B1,MYH14,PACSIN1,HSPA2,SOD1,MBP,EZR,SCRIB,ATP1B1,ITPR3,SLC25A5,VCP,CNTNAP1,ATP1A1,SLC25A4,PRDX3,PITPNA,MDH1,ARF6,DLAT |
| 8.561e-03 | -4.76 | inner ear morphogenesis | biological process | GO:0042472 | 98 | 24 | 16441 | 2455 |
CTHRC1,SOD1,USH1C,SOX9,GATA3,SCRIB,SIX4,ABR,FZD6,GBX2,FGFR2,GATA2,TBX1,PTK7,LRIG1,TBX18,ALDH1A3,NR4A3,TFAP2A,NTN1,WNT3A,GFI1,SPRY2,DVL2 |
| 8.561e-03 | -4.76 | polyol metabolic process | biological process | GO:0019751 | 98 | 24 | 16441 | 2455 |
GALK1,INPPL1,INPP5D,CALM1,CALM3,ISYNA1,SPTLC2,EPM2A,SGPP1,CALM2,PLCG1,INPP5E,PLCH1,PTEN,OCRL,IMPAD1,PLCG2,INPP4B,DGAT2,AKR1B1,GOT1,MINPP1,ITPKA,PLCB2 |
| 8.572e-03 | -4.76 | PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) | protein interactions | 5300 | 232 | 51 | 16036 | 2547 |
TAB3,TRAF2,TP53,ERBB2,CCNB1,SPR,STIL,ADAMTSL4,MOCS1,REPS1,CHPF,TP73,TOP2A,CCND1,FOXP2,WEE1,DAZAP1,CTNNB1,BCL6,CDKN1B,TAGLN2,HEXIM2,PIM1,TFG,LRIF1,MYT1,GPX4,MDFI,PLK1,SOD1,TNIP1,UBE2A,RUNX3,KIF20B,PKMYT1,PRRC1,PKM,ZBTB7B,CDC25C,CDK1,SNX12,LEPR,SOCS3,NCOA3,CARHSP1,NAB2,NFKBIA,MAP3K11,HDAC1,TBC1D4,DMPK |
| 8.602e-03 | -4.76 | MODULE_124 | MSigDB lists | MODULE_124 | 95 | 23 | 17758 | 2588 |
PLK1,NEK4,CDKN1C,PTTG1,NDC80,KIF23,KIF2C,DUSP4,CCNB1,GTF2A2,CDK1,WEE1,CCNA2,GTF2F2,E2F1,KIF22,KPNA2,BUB1,KNTC1,GFI1,CCNB2,UBE2C,RAD21 |
| 8.606e-03 | -4.76 | KINASE_BINDING | MSigDB lists | KINASE_BINDING | 69 | 18 | 17758 | 2588 |
AKAP3,BCAR1,MAPK8IP1,PICK1,BCL10,CDKN2C,TOP2A,RB1,INSR,IRAK1,IGF1R,PRDX3,KIF13B,DLG1,NOD2,CDKN2D,CCDC88A,ZC3HC1 |
| 8.606e-03 | -4.76 | KEGG_LONG_TERM_POTENTIATION | MSigDB lists | KEGG_LONG_TERM_POTENTIATION | 69 | 18 | 17758 | 2588 |
PPP1R12A,RPS6KA1,CALM1,GRIN1,CALM3,ITPR2,ITPR3,PRKACA,GRM5,CALM2,RPS6KA2,ITPR1,PPP1CB,GRIN2D,PPP1CA,PLCB2,RPS6KA3,CAMK2G |
| 8.609e-03 | -4.75 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP | 155 | 34 | 17758 | 2588 |
PLA2G4A,ETV5,GATA3,DHRS3,PNPLA5,NRP2,IL17RB,ANK1,ADORA1,TIMP1,REEP1,SGK1,RAB27B,ZNF365,SYTL3,EPB41L5,CD55,STAT4,DCHS1,STRADB,MEST,RHOB,CD8A,CTNS,CSF1,SPINT2,ZNF704,MAOA,EFNA5,PRIMA1,SHOX2,PKIA,CSRP2,NIPA1 |
| 8.609e-03 | -4.75 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN | 155 | 34 | 17758 | 2588 |
FAM89A,UGT8,IL15RA,SERPINE2,WDTC1,TMEM170B,PJA2,NUP62CL,DUSP5,RGS3,KCNN4,GPC3,OSBPL3,DRAM1,ACSL4,DUSP1,CXXC5,B3GNT2,PTPN9,PHLDB3,PLAUR,EIF5A2,DUSP4,TYSND1,RHOB,TRAM2,SH2D3C,ISM1,KLF11,EFNA1,GEM,ICOSLG,MAFF,L1CAM |
| 8.611e-03 | -4.75 | regulation of nucleoside metabolic process | biological process | GO:0009118 | 48 | 14 | 16441 | 2455 |
PRKAA2,PPIF,PINK1,RHOA,INSR,PRKAG2,DNM1L,PRKAA1,PPARA,TP53,P2RX7,ARNT,VCP,IER3 |
| 8.611e-03 | -4.75 | cellular response to hydrogen peroxide | biological process | GO:0070301 | 48 | 14 | 16441 | 2455 |
PPIF,SIRT1,KLF2,PDCD10,CST3,PRKAA1,AKR1B1,OSER1,MAP3K5,HDAC6,MAPK7,ETS1,RHOB,CYP1B1 |
| 8.611e-03 | -4.75 | labyrinthine layer development | biological process | GO:0060711 | 48 | 14 | 16441 | 2455 |
HES1,HS6ST1,NCOA3,GRHL2,AKT1,CYR61,ST14,FGFR2,SPINT2,FZD5,GAB1,TMED2,SOCS3,EGLN1 |
| 8.611e-03 | -4.75 | regulation of ATP metabolic process | biological process | GO:1903578 | 48 | 14 | 16441 | 2455 |
PRKAA2,PPIF,PINK1,RHOA,INSR,PRKAG2,DNM1L,PRKAA1,PPARA,TP53,P2RX7,ARNT,VCP,IER3 |
| 8.611e-03 | -4.75 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:2001239 | 48 | 14 | 16441 | 2455 |
FYN,SRPX,AKT1,RET,BAX,STRADB,NRG1,PPP1CA,BCL2L1,MAPK7,UNC5B,IFI6,ZC3HC1,FAS |
| 8.617e-03 | -4.75 | Glucose metabolism | REACTOME pathways | R-HSA-70326 | 77 | 20 | 8202 | 1235 |
GAA,PGM1,ENO2,UGP2,PFKFB2,SLC25A13,CALM1,PYGL,CALM3,PKM,PRKACA,EPM2A,CALM2,PFKL,GYS1,MDH1,GOT1,PHKA2,PPP2R5D,PHKG2 |
| 8.617e-03 | -4.75 | FCERI mediated NF-kB activation | REACTOME pathways | R-HSA-2871837 | 77 | 20 | 8202 | 1235 |
PSMB4,TAB3,PSME2,PSMD7,PSMD10,CUL1,PRKCQ,PSME1,PSMA4,RASGRP2,BCL10,PSMD1,PSMD3,NFKBIA,PSMC2,UBE2D2,MAP3K7,PSMC1,PSMA5,RASGRP1 |
| 8.621e-03 | -4.75 | clear_cell_papillary_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_papillary_renal_cell_carcinoma | 10 | 5 | 17775 | 2585 |
IDH1,PTEN,EGFR,PIK3CA,TP53 |
| 8.621e-03 | -4.75 | lung-carcinoma-blastoma | COSMIC cancer mutations | lung-carcinoma-blastoma | 10 | 5 | 17775 | 2585 |
ERBB2,CTNNB1,EGFR,PIK3CA,TP53 |
| 8.621e-03 | -4.75 | central_nervous_system-parietooccipital-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-parietooccipital-glioma-oligodendroglioma_Grade_II | 10 | 5 | 17775 | 2585 |
CDKN2C,IDH1,PTEN,EGFR,TP53 |
| 8.621e-03 | -4.75 | lung-carcinoma-micropapillary_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-micropapillary_adenocarcinoma | 10 | 5 | 17775 | 2585 |
KIF5B,ERBB2,EGFR,SDC4,PIK3CA |
| 8.621e-03 | -4.75 | carcinosarcoma | COSMIC cancer mutations | carcinosarcoma | 10 | 5 | 17775 | 2585 |
ERBB2,CTNNB1,EGFR,PIK3CA,TP53 |
| 8.621e-03 | -4.75 | bone-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-chondrosarcoma-dedifferentiated | 10 | 5 | 17775 | 2585 |
GNAS,SS18,IDH1,PIK3CA,TP53 |
| 8.621e-03 | -4.75 | cervical_intraepithelial_neoplasia_Grade_III | COSMIC cancer mutations | cervical_intraepithelial_neoplasia_Grade_III | 10 | 5 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 8.621e-03 | -4.75 | kidney-carcinoma-clear_cell_papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_papillary_renal_cell_carcinoma | 10 | 5 | 17775 | 2585 |
IDH1,PTEN,EGFR,PIK3CA,TP53 |
| 8.621e-03 | -4.75 | micropapillary_adenocarcinoma | COSMIC cancer mutations | micropapillary_adenocarcinoma | 10 | 5 | 17775 | 2585 |
KIF5B,ERBB2,EGFR,SDC4,PIK3CA |
| 8.621e-03 | -4.75 | cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III | COSMIC cancer mutations | cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III | 10 | 5 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 8.623e-03 | -4.75 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle | 26 | 9 | 17775 | 2585 |
RB1,CTNNB1,CDH1,AKT1,PTEN,PIK3CA,TP53,FLT3,EGFR |
| 8.623e-03 | -4.75 | glomus_tumour | COSMIC cancer mutations | glomus_tumour | 26 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 8.623e-03 | -4.75 | biliary_tract-gallbladder-carcinoma-adenosquamous_carcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-adenosquamous_carcinoma | 26 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 8.623e-03 | -4.75 | adenosquamous_carcinoma | COSMIC cancer mutations | adenosquamous_carcinoma | 26 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 8.623e-03 | -4.75 | soft_tissue-blood_vessel-glomus_tumour | COSMIC cancer mutations | soft_tissue-blood_vessel-glomus_tumour | 26 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 8.672e-03 | -4.75 | duodenum | COSMIC cancer mutations | duodenum | 35 | 11 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,AKT1,RET,MSH2,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 8.699e-03 | -4.74 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | MSigDB lists | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | 64 | 17 | 17758 | 2588 |
PLK1,PSMB4,PSME2,CDC20,PTTG1,PSMD7,PSMD10,PSME1,AURKB,PSMA4,PSMD1,PSMD3,PSMC2,AURKA,UBE2C,PSMC1,PSMA5 |
| 8.701e-03 | -4.74 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | MSigDB lists | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | 10 | 5 | 17758 | 2588 |
PRKAA2,TSC1,PRKAG2,RHEB,PRKAA1 |
| 8.701e-03 | -4.74 | REGULATION_OF_RHO_GTPASE_ACTIVITY | MSigDB lists | REGULATION_OF_RHO_GTPASE_ACTIVITY | 10 | 5 | 17758 | 2588 |
FGD6,TSC1,RALBP1,ARAP1,FGD1 |
| 8.701e-03 | -4.74 | PROTEIN_PHOSPHATASE_BINDING | MSigDB lists | PROTEIN_PHOSPHATASE_BINDING | 10 | 5 | 17758 | 2588 |
SOD1,BCAR1,PPME1,PPP2R4,PIK3R1 |
| 8.701e-03 | -4.74 | OXIDOREDUCTASE_ACTIVITY_GO_0016706 | MSigDB lists | OXIDOREDUCTASE_ACTIVITY_GO_0016706 | 10 | 5 | 17758 | 2588 |
PLOD3,PLOD2,P4HB,P4HA2,EGLN1 |
| 8.701e-03 | -4.74 | LYSOSOMAL_TRANSPORT | MSigDB lists | LYSOSOMAL_TRANSPORT | 10 | 5 | 17758 | 2588 |
NAGPA,ZFYVE16,ARSB,RHOB,M6PR |
| 8.701e-03 | -4.74 | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN | MSigDB lists | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN | 10 | 5 | 17758 | 2588 |
KIF2C,CCNA2,CCNB1,CDC20,CKS2 |
| 8.701e-03 | -4.74 | REACTOME_IL_6_SIGNALING | MSigDB lists | REACTOME_IL_6_SIGNALING | 10 | 5 | 17758 | 2588 |
JAK1,CBL,IL6ST,STAT1,SOCS3 |
| 8.701e-03 | -4.74 | CHROMOSOME_CONDENSATION | MSigDB lists | CHROMOSOME_CONDENSATION | 10 | 5 | 17758 | 2588 |
TOP2A,NUSAP1,AIFM2,CDCA5,SMC4 |
| 8.701e-03 | -4.74 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | MSigDB lists | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | 10 | 5 | 17758 | 2588 |
DAPK2,CASP3,UNC5B,CASP9,DAPK1 |
| 8.717e-03 | -4.74 | ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 122 | 28 | 17758 | 2588 |
SEC61B,SLC25A13,ABCG2,SLC1A3,SLC17A5,SLC7A2,ATP1B1,SLC20A1,SLC9A2,SLC9A7,ABCD4,TAPBP,SLC6A6,ATP1A1,CTNS,SLC4A4,ATP7B,SLC9A6,SLC44A1,SLC4A3,SLC44A2,ATP8B1,ATP1B3,ATP6V1C1,SLC12A2,ATP2B1,ABCG1,ABCC1 |
| 8.719e-03 | -4.74 | chr12q23 | MSigDB lists | chr12q23 | 59 | 16 | 17758 | 2588 |
CDK17,ELK3,NUAK1,DEPDC4,AMDHD1,UHRF1BP1L,ANKS1B,ARL1,GNPTAB,DRAM1,FGD6,NUP37,ANO4,C12orf75,CKAP4,CCDC38 |
| 8.721e-03 | -4.74 | V$FREAC4_01 | MSigDB lists | V$FREAC4_01 | 144 | 32 | 17758 | 2588 |
HSPG2,OSR2,CAMK1D,PHLPP1,PPP2R3A,ZNF385B,PER2,SCML1,PLS3,CD109,FOXP2,SNX13,ZFX,FRY,CALD1,LMO4,VASN,ETHE1,CITED2,CLIP2,BTBD3,MAST4,DUSP1,NR4A1,ROR1,PITX2,KLF12,PELI2,KBTBD2,SPRY4,SHOX2,RARG |
| 8.737e-03 | -4.74 | PICK1 (protein interacting with PRKCA 1) | protein interactions | 9463 | 78 | 21 | 16036 | 2547 |
PVRL4,GRIK2,CEP89,ITGA6,RASSF7,ERBB2,F11R,ERBB2IP,DSE,NDRG3,QSOX2,EFNB1,PICK1,CTNNB1,PVRL2,ATXN7L3,GNPTAB,UACA,FAM117A,PKD2,GFI1 |
| 8.743e-03 | -4.74 | KEGG_GALACTOSE_METABOLISM | MSigDB lists | KEGG_GALACTOSE_METABOLISM | 26 | 9 | 17758 | 2588 |
GAA,GALK1,PGM1,UGP2,PFKL,MGAM,AKR1B1,GLB1,GLA |
| 8.743e-03 | -4.74 | BIOCARTA_BAD_PATHWAY | MSigDB lists | BIOCARTA_BAD_PATHWAY | 26 | 9 | 17758 | 2588 |
IGF1R,AKT1,RPS6KA1,PIK3R1,PIK3CA,BAX,PRKAR2B,BCL2L1,PRKAR1A |
| 8.743e-03 | -4.74 | PID_P38_MKK3_6PATHWAY | MSigDB lists | PID_P38_MKK3_6PATHWAY | 26 | 9 | 17758 | 2588 |
MAP3K3,TAOK2,TXN,TRAF2,CCM2,MAPK11,MAP3K5,MAP3K7,MAP3K6 |
| 8.743e-03 | -4.74 | chr12q22 | MSigDB lists | chr12q22 | 26 | 9 | 17758 | 2588 |
BTG1,HAL,NTN4,VEZT,NDUFA12,LTA4H,NR2C1,TMCC3,METAP2 |
| 8.743e-03 | -4.74 | BIOCARTA_RACCYCD_PATHWAY | MSigDB lists | BIOCARTA_RACCYCD_PATHWAY | 26 | 9 | 17758 | 2588 |
CCND1,RB1,RHOA,AKT1,NFKBIA,PIK3R1,PIK3CA,E2F1,CDKN1B |
| 8.743e-03 | -4.74 | JI_METASTASIS_REPRESSED_BY_STK11 | MSigDB lists | JI_METASTASIS_REPRESSED_BY_STK11 | 26 | 9 | 17758 | 2588 |
TNS4,LTBP1,EPAS1,AREG,GDF15,LIMCH1,DUSP4,F2RL1,CYP1B1 |
| 8.743e-03 | -4.74 | HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_DN | MSigDB lists | HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_DN | 26 | 9 | 17758 | 2588 |
GRN,TOP2A,KLK10,ZWINT,ITGA6,DSTN,PRKCI,KLK7,LGALS3BP |
| 8.743e-03 | -4.74 | YANG_BREAST_CANCER_ESR1_BULK_UP | MSigDB lists | YANG_BREAST_CANCER_ESR1_BULK_UP | 26 | 9 | 17758 | 2588 |
TMBIM6,TSPAN13,BLVRA,COX6C,TSPAN1,FOXA1,MYO5C,FAM134B,ABCG1 |
| 8.743e-03 | -4.74 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE | 26 | 9 | 17758 | 2588 |
B3GALT6,HS6ST1,XYLT2,XYLT1,HS3ST3B1,EXT2,NDST3,GLCE,HS6ST3 |
| 8.743e-03 | -4.74 | PID_VEGFR1_PATHWAY | MSigDB lists | PID_VEGFR1_PATHWAY | 26 | 9 | 17758 | 2588 |
PGF,PLCG1,AKT1,PIK3R1,PIK3CA,CBL,PRKACA,RASA1,NRP2 |
| 8.752e-03 | -4.74 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP | 189 | 40 | 17758 | 2588 |
SUN1,LZTFL1,ZNF395,ATP8A1,AES,ISYNA1,CCNL1,ERP29,LTBP3,RSAD1,MARCH8,CTNNBIP1,ADD3,STIM1,KLF3,FXYD5,VAT1,WWP1,PHKA2,FLOT2,ADCK3,PAPD7,BNIP3L,STMN3,KIAA1109,RASGRP2,TRAM2,BTG1,ATP1A1,TJP3,FAAH,STAT6,RYK,ARRB1,EIF4EBP2,CDK18,CABIN1,LSM14B,CBX7,PHC1 |
| 8.752e-03 | -4.74 | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_DN | 189 | 40 | 17758 | 2588 |
DOC2A,DHPS,RUSC2,RASA2,SOD2,DNAJB11,FAM81A,PJA2,REPS1,RPS6KA2,ARTN,DPYSL2,LMO4,SNX16,CD70,MAPK11,MDFIC,TAGLN2,CACNA1D,EGLN3,MYBL1,IL10RB,CPD,GCA,FXR2,CYFIP2,VCP,SFXN1,HOXA9,PLK2,AGBL5,TDRD7,ARFGAP3,HDAC1,KLF5,TTC39C,ICOSLG,TRAF5,AHR,SRSF9 |
| 8.752e-03 | -4.74 | GSE27786_NEUTROPHIL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NEUTROPHIL_VS_MONO_MAC_UP | 189 | 40 | 17758 | 2588 |
PLEKHG3,GSDMD,PCOLCE,DGKA,MPP5,TRAPPC8,MGAT5B,SDF4,DNAH6,AIM1,FAM63A,RAB20,RGS5,TSPAN13,RP2,C10orf54,CTSD,CERS2,CDKN2AIP,B3GNT2,MBP,TACC1,NR3C1,FOPNL,AMFR,BBS2,TP53INP2,CASP4,TBC1D17,SERTAD2,DCK,SIPA1L1,AGBL5,ACADM,AKNA,TMEM159,CMPK2,PRKAR1A,ARHGEF4,TMEM131 |
| 8.752e-03 | -4.74 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | 189 | 40 | 17758 | 2588 |
CCNC,ANXA3,ENO2,SLC41A1,DNAJB2,SERPINB9,FHDC1,PDIA5,UBE2Z,BLCAP,FTH1,SNX9,FAM46C,KTN1,LMNA,M6PR,IMPAD1,ADAM15,LGMN,NEK4,TGIF1,ADAM17,B3GNT2,PLSCR1,STAT4,PIK3R1,RNF11,VPS4B,LITAF,PTGFRN,CASP4,STX3,ARF4,CD83,ONECUT1,TIMM8A,PLK2,PTGES,ANXA11,PCSK5 |
| 8.752e-03 | -4.74 | GSE3982_EOSINOPHIL_VS_DC_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_DN | 189 | 40 | 17758 | 2588 |
CD99,MRC2,ST13,UGP2,NQO1,VANGL1,HEBP1,ADO,SDC4,BARD1,PPP2R3A,ABCD4,CORO1B,PDGFA,CTSC,LMAN2L,OSBPL3,ADCK2,TFG,TRAM1,GM2A,CCDC88A,WBP5,ALDH2,MRPS33,ACO1,SESN1,ALCAM,RHEB,CD83,FASTKD1,STAT6,OTUB2,MDH1,PIK3C2B,HSPB1,CBX5,CCNB2,ACOT7,PCSK5 |
| 8.764e-03 | -4.74 | TGCCAAR_V$NF1_Q6 | MSigDB lists | TGCCAAR_V$NF1_Q6 | 683 | 122 | 17758 | 2588 |
ACVR1,TTC39B,TMEM86B,CAMKK1,RHBDL3,SUDS3,WDTC1,ERBB2,NDRG2,FAM91A1,PRKACA,ECI1,SYTL2,SLC25A35,PER2,PLS3,CALM2,CDKN2C,PHYHIP,FAM46A,ARTN,STIM1,DACT1,TSPAN6,LMO4,MITF,ANKFN1,BCL6,ANKRD12,GOT1,ARL4D,DLG3,OSBPL7,SNX10,ETV4,OLFML2A,ZNF462,SMARCA2,CD55,TRIM8,FZD4,ACO1,C12orf65,KIF13A,ROR1,DUSP4,EBF2,NFIX,IRS2,KLF12,PTK7,HAGHL,SP6,SPRY4,LIFR,NR3C2,CBX4,RMND5A,FBLIM1,SCOC,CPEB4,IGFBP6,LRRFIP2,ESRP1,ETV5,MIER3,ATP6V1E2,CALM3,C6orf106,DHRS3,TSPAN7,SRPX2,PGAP1,NRP2,H1FX,LMNA,MECOM,FOXP2,ADD3,CYR61,CALD1,KIF13B,FLRT3,ZIC5,FAM13B,RRBP1,CACNA1D,NCAM1,MOXD1,CITED2,MAST4,RBMS2,CKAP4,AMOTL2,PLEKHA6,NUDT8,CALM1,RC3H2,VWA1,NFIB,RANBP9,ABLIM2,GPLD1,KLHL2,XKRX,CRTC2,PITX2,AP1AR,TIMP3,SMTNL2,TIMM8A,H1F0,MFSD2A,ITGA7,SERPINB5,LTBP2,LRRK1,PER3,OSR1,SHOX2,KLF7,XDH |
| 8.779e-03 | -4.74 | lipid localization | biological process | GO:0010876 | 258 | 53 | 16441 | 2455 |
PLA2G4A,PRKAA2,ACACB,CPT2,ATP9A,PNPLA2,ATP8A1,APOO,HEXB,ABCG4,P2RX7,ANO9,B4GALNT1,SLC27A6,OSBPL3,KCNN4,FABP6,ABCA2,ATP8B1,SORL1,ABCD1,ACSL4,OSBPL7,ANO4,GM2A,NCOA2,SOAT1,ACVR1C,FZD4,ANO6,VPS4B,PPARA,NPC2,ATP8B3,ESYT1,PCTP,CPTP,ATP10D,SPNS3,PLIN5,OSBPL2,ENPP1,LDLRAP1,PRKAG2,TMEM30A,MFSD2A,DGAT2,SLC27A1,PITPNA,APOL2,ABCA1,ESYT2,ABCG1 |
| 8.783e-03 | -4.73 | maintenance of location in cell | biological process | GO:0051651 | 93 | 23 | 16441 | 2455 |
SUN1,SUN2,GAA,PINK1,NFKBIE,AKT1,SYNE3,THRA,ASPM,SYNE2,EZR,KDELR3,PSMD10,PDIA3,FTH1,DAG1,NFKBIA,SORL1,PKD2,SUN3,TLN2,KDELR1,MDFI |
| 8.784e-03 | -4.73 | MODULE_55 | MSigDB lists | MODULE_55 | 808 | 142 | 17758 | 2588 |
MYL9,BCAM,HSPG2,EPAS1,CRYM,NRG2,PLA2G16,SDC1,ECI1,CARD10,DAPK2,EPCAM,ZYX,PHYHIP,ALDH1A3,DNM2,TACSTD2,ACOX2,SMAGP,SGCE,CD55,CDA,F12,ICMT,CCNF,TCN2,ENPP1,MYLK,BMP1,NRGN,GRN,PRSS8,CYP2J2,DNAJB2,ITGA6,SOX9,DHRS3,TSPAN7,SPP1,RAC2,CA2,ITGA3,CYR61,LYPD3,GATA2,CD22,KCNN4,NECAB3,BDH1,TBCD,COL6A1,PLCB2,ALDH3A2,RIMS2,EPHX1,FADS2,PYGL,TCF7,DPYSL4,RHOB,EGFR,CDK5R1,CYB5A,IL1R1,NAAA,SLC4A4,ETS2,PVRL2,FAAH,RAB31,SLC4A3,CDK18,EFNA1,JAK3,XDH,PAX6,NQO1,S100A11,THRA,PTTG1,GMPR,COL18A1,PHLDA1,APC2,IER3,CCND1,SCNN1A,CDH1,SRPX,TACC2,GOT1,IFIT1,LGMN,HSPA2,CKS2,COL6A2,PFKFB2,S100A4,CDC20,MAOA,ABCA1,GCLM,PINK1,PCOLCE,ATP9A,DCAF7,GNE,BLVRB,GDF15,SEPP1,DNAH3,HOXB2,ITGA2B,RND1,LLGL2,GPC3,GALNS,TFAP2A,ALDH7A1,IGFBP2,ERBB3,CITED2,HCN3,SHMT1,WNT10B,NR4A1,GCLC,FURIN,EMP3,AK4,COL7A1,FOS,PROM1,TIMP3,SERPINA1,DHRS2,DTX4,ARFGAP3,UBE2C,L1CAM,OCLN,CD33 |
| 8.787e-03 | -4.73 | Diacylglycerol_kin_accessory | interpro domains | IPR000756 | 10 | 5 | 18293 | 2672 |
DGKH,DGKG,DGKE,DGKQ,DGKA |
| 8.787e-03 | -4.73 | Filamin/ABP280_rpt | interpro domains | IPR001298 | 10 | 5 | 18293 | 2672 |
TRIM3,TRIM2,AREL1,KDELC2,TRIM45 |
| 8.787e-03 | -4.73 | Pept_asp_AS | interpro domains | IPR025661 | 10 | 5 | 18293 | 2672 |
CTSL,CTSZ,CTSC,CTSB,CTSV |
| 8.793e-03 | -4.73 | G13 Signaling Pathway | WikiPathways | WP524 | 40 | 13 | 4455 | 729 |
CALM2,RHOA,CIT,IQGAP1,LIMK1,CALM1,PIK3CA,PPP1CB,RHPN2,CALM3,ARHGDIB,PIK3CD,PKN1 |
| 8.793e-03 | -4.73 | Interleukin-11 Signaling Pathway | WikiPathways | WP2332 | 40 | 13 | 4455 | 729 |
PIAS3,RUNX2,FYN,AKT1,JAK1,IL6ST,RPS6KA1,PIK3R1,PPP2R4,STAT1,YES1,ICAM1,SOCS3 |
| 8.797e-03 | -4.73 | Signaling by WNT in cancer | REACTOME pathways | R-HSA-4791275 | 34 | 11 | 8202 | 1235 |
KREMEN2,PPP2R5A,CTNNB1,FZD4,AMER1,WNT3A,FZD5,PPP2R5D,KREMEN1,CTBP1,FZD6 |
| 8.797e-03 | -4.73 | DAG and IP3 signaling | REACTOME pathways | R-HSA-1489509 | 34 | 11 | 8202 | 1235 |
CALM2,PLCG1,ADRBK1,ITPR1,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PRKAR1A |
| 8.804e-03 | -4.73 | negative regulation of intracellular transport | biological process | GO:0032387 | 130 | 30 | 16441 | 2455 |
TXN,ERLEC1,BAG4,NFKBIE,THRA,DMTN,LITAF,RAB23,PSMD10,SLC25A5,BARD1,APC2,SNX12,MAP1B,IER3,NOV,SP100,BMP7,CABP1,WWTR1,NFKBIA,UBE2J1,DAB2IP,PKD2,MDFIC,YOD1,MAPK7,PKIA,MDFI,CHP1 |
| 8.810e-03 | -4.73 | PID_ARF6_PATHWAY | MSigDB lists | PID_ARF6_PATHWAY | 35 | 11 | 17758 | 2588 |
ARAP2,ACAP2,KIF13B,FBXO8,ARRB1,EFNA1,ARF6,GNA11,EGFR,ITGA2B,USP6 |
| 8.810e-03 | -4.73 | ST_G_ALPHA_I_PATHWAY | MSigDB lists | ST_G_ALPHA_I_PATHWAY | 35 | 11 | 17758 | 2588 |
PITX2,AKT1,ITPR1,RGS20,ASAH1,ITPR2,ITPKA,ITPR3,PLCB2,DAG1,EGFR |
| 8.810e-03 | -4.73 | HOUSTIS_ROS | MSigDB lists | HOUSTIS_ROS | 35 | 11 | 17758 | 2588 |
GCLM,SOD1,TXN,PRDX3,SDC4,SOD2,FTH1,XDH,PRDX4,GPX4,CYP1B1 |
| 8.817e-03 | -4.73 | regulation of stem cell differentiation | biological process | GO:2000736 | 114 | 27 | 16441 | 2455 |
EPB41L5,HES1,SOX9,RGCC,PRICKLE1,TGFBR1,SAV1,LTBP3,DAG1,TEAD3,SIX4,CNOT2,BMP2,NCOA3,CTNNB1,BMP7,VASN,WWTR1,SMO,DAB2IP,TACSTD2,TWIST1,C10orf54,EFNA1,WNT3A,TRIM62,FOXA1 |
| 8.817e-03 | -4.73 | spindle organization | biological process | GO:0007051 | 114 | 27 | 16441 | 2455 |
SUN2,RHOA,SPC25,ASPM,NDC80,XIAP,MYBL2,KIF23,EZR,RACGAP1,AURKB,STIL,KIF11,CKAP5,DCTN6,TACC2,PLK2,TUBGCP6,PPP2R4,DLG1,PRC1,NEK2,TUBG1,AURKA,RGS14,WDR62,ESPL1 |
| 8.827e-03 | -4.73 | negative regulation of cell development | biological process | GO:0010721 | 281 | 57 | 16441 | 2455 |
SEMA6B,PAX6,ADGRG1,CIT,SOX9,EPHA4,LRP4,TP53,FAM101B,FBLN1,TP73,CALR,SPP1,CTNNB1,PTEN,BMP7,VASN,KIAA0319,DUSP10,SORL1,DAB2IP,DIXDC1,TACSTD2,SEMA3G,NOTCH3,NTN1,WNT3A,GFI1,ITM2C,TTPA,TRIM62,SEMA3B,HES1,RHOA,MFI2,ASPM,DMTN,RAPGEF2,CDK5R1,ULK2,IRX3,DPYSL3,AP1AR,SEMA4D,PLK2,CORO1C,STAT1,NRG1,RAB29,GDF11,EFNA1,SOX8,ARF6,SEMA3A,FOXA1,NGEF,CTDSP1 |
| 8.846e-03 | -4.73 | spinal_cord | COSMIC cancer mutations | spinal_cord | 150 | 33 | 17775 | 2585 |
ACVR1,NF2,RET,FHDC1,TP53,ERBB2,FLT3,RB1,CTNNB1,CDH1,DNAH6,PTEN,FRYL,ATP13A3,MSH2,SMO,MAP3K9,PIK3CA,ESPN,RP2,MSH6,QSOX1,AKT1,PIK3R1,TEP1,IDH1,EGFR,GNAS,FGFR2,MATN2,CCNB2,JAK3,XDH |
| 8.894e-03 | -4.72 | ABCA1 (ATP binding cassette subfamily A member 1) | protein interactions | 19 | 50 | 15 | 16036 | 2547 |
SNTA1,LMO7,PDLIM3,UGP2,ARHGEF11,LIMK1,SNTB2,FLOT1,AOX1,ERBB2IP,SNTB1,DLG3,PRKACA,TIAM1,RIMS2 |
| 8.917e-03 | -4.72 | epithelial cell development | biological process | GO:0002064 | 196 | 42 | 16441 | 2455 |
EXPH5,PAX6,GRHL2,ST14,FRMD6,IQGAP1,SOX9,CCM2,GATA3,COL18A1,F11R,SDC1,PDGFB,TMC1,ICAM1,CTNNB1,CST3,SMO,ACTA2,PDE4D,EPB41L5,SOD1,RAPGEF2,EZR,TFAP2C,SCRIB,FNDC3A,FZD7,ARHGEF26,ONECUT1,BFSP1,FGFR2,SHROOM3,SPINT2,RAP2C,KLF5,HOXB13,PLOD3,SOX8,F2RL1,RARG,FOXA1 |
| 8.957e-03 | -4.72 | integrin binding | molecular function | GO:0005178 | 104 | 25 | 16491 | 2452 |
TIMP2,ADAM17,FBLN5,NF2,ITGA6,UTRN,ERBB2IP,ILK,FBLN1,EMP2,ICAM1,CALR,NOV,ITGA3,CTGF,CYR61,NPNT,P4HB,PLPP3,ICAM5,CD9,ADAM15,SYK,L1CAM,COL16A1 |
| 8.959e-03 | -4.72 | CAIRO_LIVER_DEVELOPMENT_UP | MSigDB lists | CAIRO_LIVER_DEVELOPMENT_UP | 161 | 35 | 17758 | 2588 |
SERPINE2,NES,HMGN3,SNN,CRABP2,CDK14,NEO1,PLS3,RCN1,KCTD15,TSPAN6,FLRT3,DLG3,SLC12A2,MGAT5,PDGFC,TGIF1,SMARCA2,CAPN6,SEPT6,SYNE2,DUSP4,LDB2,MEST,RHOB,MDK,PITX2,TMEM50B,PAFAH1B3,SLC25A4,PLOD2,PLK2,SEMA3A,AFAP1,CSRP2 |
| 8.961e-03 | -4.71 | ATPase_P-typ_cyto_domN | interpro domains | IPR023299 | 35 | 11 | 18293 | 2672 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP13A3,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 8.966e-03 | -4.71 | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN | MSigDB lists | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN | 106 | 25 | 17758 | 2588 |
PLEKHA6,FBXL16,GRHL2,SERTAD4,FXYD3,BIK,MTL5,RET,GATA3,ERBB2,PLA2G16,COX6C,NPDC1,MYO5C,EPN3,EPCAM,RTN4RL1,AP1M2,SLC25A4,CDH1,NAT1,SPINT2,ACOX2,MAL2,FOXA1 |
| 8.974e-03 | -4.71 | exocytic vesicle | cellular component | GO:0070382 | 10 | 5 | 17570 | 2579 |
RAB6A,SYTL4,SYTL3,SYTL2,DPYSL3 |
| 8.974e-03 | -4.71 | contractile ring | cellular component | GO:0070938 | 10 | 5 | 17570 | 2579 |
KIF20B,ANLN,DAG1,PRC1,UTRN |
| 8.988e-03 | -4.71 | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN | 195 | 41 | 17758 | 2588 |
HSP90B1,ST13,LGALS3,SOD2,PRSS22,ISYNA1,SLC20A1,PHLDA1,ELF3,CALR,EPCAM,SPP1,PCNA,RANBP1,CKS1B,TRIM3,BUB1,MANF,S100A6,CKAP4,CKS2,WBP5,SEC23A,KIF20A,GCLC,PBK,LITAF,KDELR3,NPC2,MCFD2,TXNDC11,CDK1,SOCS3,UAP1,AREG,OSMR,KPNA2,ALG2,SPCS3,CCNB2,ACOT7 |
| 8.988e-03 | -4.71 | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 195 | 41 | 17758 | 2588 |
SORBS1,RUNX2,IL15,PARP14,CAMKK1,TSC22D3,IL13RA1,CCNL1,MGST2,CARD10,ATP6V0B,DOPEY2,IGF1R,PIK3AP1,ARSG,BCL6,IRF2,IFIT1,C10orf54,PIM1,GFI1,MYLIP,SPRY2,SNED1,CKAP4,XKR8,MAP3K3,CPD,SNTB2,NUB1,SERTAD3,BTBD19,MGAM,PYGL,LDB2,SFXN5,GALNT3,BTG1,SH2D3C,MAP3K5,FAM134B |
| 9.023e-03 | -4.71 | Rab guanyl-nucleotide exchange factor activity | molecular function | GO:0017112 | 30 | 10 | 16491 | 2452 |
ST5,DENND1B,MADD,RIN3,RAB3IP,SBF1,RIC1,DENND2D,RAB3IL1,DENND5B |
| 9.023e-03 | -4.71 | ADP binding | molecular function | GO:0043531 | 30 | 10 | 16491 | 2452 |
ATP1A1,PRKAG2,ADCK3,GCLC,PRPS2,MSH2,TAP1,MSH6,VCP,ABCG1 |
| 9.036e-03 | -4.71 | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | MSigDB lists | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 178 | 38 | 17758 | 2588 |
DHPS,MAN1A2,GALNT12,PDIA3,B4GALT4,PIGL,PGAP1,CALR,MUC16,MGAT1,ARSG,ALG13,MGAT4A,FUT8,RPN2,LMAN1,MGAT5,GCNT1,PIGC,B3GNT7,SEC23A,B3GNT2,MLEC,PLAUR,MGAT4B,EIF5A2,FURIN,C1GALT1C1,GALNT7,MCFD2,ARSK,GALNT3,DDOST,DOLPP1,ALG2,B4GALT3,ARSB,ST3GAL1 |
| 9.036e-03 | -4.71 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | 178 | 38 | 17758 | 2588 |
TRIM2,HLA-E,FHDC1,TP53,TDRKH,CAMK1D,EMP2,SLC20A1,SSX2IP,SH3KBP1,CYR61,FJX1,ENPP5,GALNS,STEAP2,RP2,NCAM1,RPGR,MYO5A,MARK1,MOSPD2,NR3C1,PFKFB2,ACO1,CLSTN1,YES1,ANKRD29,PITX2,TRIM9,ZDHHC20,PPM1H,CSGALNACT1,PCDH19,MAOA,TTC9,GLA,CENPE,NR2C2 |
| 9.036e-03 | -4.71 | VERHAAK_AML_WITH_NPM1_MUTATED_UP | MSigDB lists | VERHAAK_AML_WITH_NPM1_MUTATED_UP | 178 | 38 | 17758 | 2588 |
PLA2G4A,LTBP1,SORT1,CAST,SOD2,PBX3,COL4A5,GDF15,RASGRP3,SEPP1,PHLDA1,HOXB2,LGALS3BP,LMNA,IER3,GNS,TYMP,KCNK5,BCL6,PHKA2,NFKB2,CTSD,SNX10,S100A6,SMC4,CYP1B1,MCTP1,PLAUR,SAT1,PRKAR2B,PLS1,SERPINA1,ETS2,NGFRAP1,HOXA9,SECTM1,NFKBIA,SLC2A6 |
| 9.036e-03 | -4.71 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_UP | 178 | 38 | 17758 | 2588 |
ELK4,TXN,SPC25,XYLT1,EPHA4,SDC4,NDUFA4,IL18,MNS1,PER2,TOP2A,SPP1,ANK1,PQLC2,TAX1BP3,TACSTD2,PTPRE,TRAM1,ERAP2,EPHX1,ADAM17,PLAUR,PBK,UBE2A,CR2,ZSCAN12,CAPNS1,BCL7B,PDK3,UAP1,PLOD2,TIMM8A,PLK2,SH3BP4,EPB41L4A,COL16A1,E2F8,NR2C2 |
| 9.102e-03 | -4.70 | secretion by cell | biological process | GO:0032940 | 499 | 94 | 16441 | 2455 |
DOC2A,ARFGEF1,P2RX7,GATA3,UBE2Q1,LGI3,BAIAP3,SYTL4,PDGFB,ERP29,SDF4,SYTL2,PDGFA,CALM2,SVBP,RAB15,CTGF,STEAP2,STEAP3,PIK3CD,ARL4D,RAB27B,S100A13,RASGRP1,TUBA4A,CHP1,LAMP2,SOD1,FZD4,DMTN,RNF19B,OPTN,TRIM9,ALDH5A1,GNPTAB,AXL,RAB11FIP1,NOD2,MAOA,SYT13,F2RL1,TC2N,ABCA1,PCSK5,ANXA3,CD63,HABP4,BTN3A1,CALM3,PLD2,SLC1A3,APBA1,MERTK,ITGA2B,PDIA4,ANK1,TIMP1,CDK16,LLGL2,GATA2,RIMS3,NECAB3,CD9,EXOC8,CADPS2,CPLX1,GAD1,SYK,SYTL3,CAMK2G,RIMS2,MYO5A,CASK,RAB3B,CALM1,FURIN,VAMP3,BTN3A2,SCRIB,AKAP3,STX3,SCRN2,GNAS,SERPINA1,SYT7,RAB11FIP2,SCG2,HTT,NR4A3,RAB31,ARFGAP3,LTBP2,PLD1,SNPH |
| 9.118e-03 | -4.70 | autophagosome | cellular component | GO:0005776 | 74 | 19 | 17570 | 2579 |
VPS11,NRBF2,RAB23,PIP4K2C,C6orf106,TP53INP2,MAP1LC3B,OPTN,GABARAPL1,DAPK2,ENTPD4,TBC1D17,SRPX,RALB,HTT,WIPI1,RPN2,OSBPL7,C9orf72 |
| 9.120e-03 | -4.70 | extracellular matrix component | cellular component | GO:0044420 | 127 | 29 | 17570 | 2579 |
LTBP1,TIMP2,FBLN5,CASK,AGRN,HSPG2,ITGA6,P3H2,COL18A1,VWA1,COL7A1,COL4A5,LOXL2,ERBB2IP,SLC1A3,FBLN1,DAG1,COL12A1,TIMP3,TIMP1,NPNT,FRAS1,CST3,COL6A1,MATN2,DLG1,NTN4,NTN1,LOXL1 |
| 9.121e-03 | -4.70 | USP20 (ubiquitin specific peptidase 20) | protein interactions | 10868 | 64 | 18 | 16036 | 2547 |
PLK1,SUN2,CALM1,PLEKHA7,PSMD7,RAD17,SYTL4,PRKACA,FECH,RGPD5,N4BP3,PRKCI,ECI2,ACADM,APBA2,CBX7,SPRY2,MDFI |
| 9.121e-03 | -4.70 | MARK2 (MAP/microtubule affinity-regulating kinase 2) | protein interactions | 2011 | 64 | 18 | 16036 | 2547 |
MAP3K3,RHOA,PINK1,MARK1,AKT1,SNTB2,PRKAA1,UTRN,AURKB,PHLPP1,VCP,KIF5B,FUCA1,RAB11FIP2,KIF13B,PPP2R4,PRKCI,GAB1 |
| 9.124e-03 | -4.70 | CTCTGGA,MIR-520A,MIR-525 | MSigDB lists | CTCTGGA,MIR-520A,MIR-525 | 150 | 33 | 17758 | 2588 |
LASP1,UBASH3B,ETV5,CTDSPL,ABCG4,C6orf106,PBX3,SDC1,ARHGEF40,GNB2,MXD1,RB1,RNF220,PTEN,ZNRF2,TNPO2,TWIST1,CAMK2G,TMCC2,GCLC,DCHS1,NFE2L1,SLC11A2,STX3,PGF,STAT6,UBE2D2,RAB11FIP1,PCDH19,HMGA1,SPRY4,PLXND1,UBE2C |
| 9.132e-03 | -4.70 | glycosaminoglycan biosynthetic process | biological process | GO:0006024 | 109 | 26 | 16441 | 2455 |
CHSY3,B3GALT6,SLC35D2,B3GNT7,B3GNT2,AGRN,HSPG2,XYLT1,SDC4,PXYLP1,B4GALT4,DSE,SDC1,EXT2,CHST2,CHPF,GLCE,HS6ST1,XYLT2,GPC3,CSGALNACT1,B4GAT1,HS3ST3B1,B4GALT3,ST3GAL1,NDST3 |
| 9.132e-03 | -4.70 | carbohydrate catabolic process | biological process | GO:0016052 | 109 | 26 | 16441 | 2455 |
GALK1,PGM1,GAA,ENO2,PFKFB2,CALM1,HEXB,OGDHL,CALM3,MGAM,PYGL,PKM,CALM2,DHDH,FUT2,PFKL,FUT8,FUT1,PGM2L1,DHTKD1,GLB1,PHKA2,PPP2R5D,PHKG2,NAGA,GM2A |
| 9.152e-03 | -4.69 | establishment of protein localization to plasma membrane | biological process | GO:0090002 | 83 | 21 | 16441 | 2455 |
GCC2,TSPAN15,FLOT1,VAMP3,PKP2,EZR,MPP5,ARFRP1,F11R,KIF13A,ATP1B1,BBS2,TSPAN17,OPTN,ANK1,CDH1,RAB31,PACSIN1,FLOT2,TSPAN33,TMED2 |
| 9.159e-03 | -4.69 | regulation of protein complex assembly | biological process | GO:0043254 | 322 | 64 | 16441 | 2455 |
ADD1,THRA,ARFGEF1,TP53,HDAC6,SNX9,SPTB,CTNNB1,RALB,LMO4,KIF14,PSMC2,MITF,DLG1,CAPG,CDKN1B,DAB2IP,TWIST1,CTTN,PLK1,PSRC1,BAG4,DMTN,PTGER4,VPS4B,VCP,LCP1,TRIM9,PEX5,IDE,DNM1L,TRAF3IP1,TRIOBP,CHMP4B,TMOD2,SPTBN5,PIEZO1,ARF6,PSMC1,FBLIM1,BMF,PINK1,HJURP,BIK,EPS8,ICAM1,CTNNBIP1,VASP,TBCD,TUBGCP6,BAX,GTF2F2,SORL1,FNIP1,SLAIN2,MAP3K7,FARP2,RHOA,WNT10B,FMN1,RASA1,FAS,ARPC2,AHR |
| 9.172e-03 | -4.69 | ANTI_APOPTOSIS | MSigDB lists | ANTI_APOPTOSIS | 117 | 27 | 17758 | 2588 |
BAG4,HSP90B1,GCLC,SERPINB9,XIAP,BNIP3L,HTATIP2,GLO1,NOTCH2,BCL2L1,GSTP1,CDK1,RASA1,FAS,SOCS3,IER3,IGF1R,SEMA4D,BAX,HDAC1,TNFRSF18,HSPB1,CDKN2D,IFI6,HIPK3,CBX4,TMX1 |
| 9.220e-03 | -4.69 | regulation of response to oxidative stress | biological process | GO:1902882 | 58 | 16 | 16441 | 2455 |
SIRT1,SOD1,TXN,PINK1,FBLN5,AKT1,SOD2,HDAC6,SESN1,SESN3,STK26,P4HB,BMP7,NR4A3,MAPK7,HSPB1 |
| 9.220e-03 | -4.69 | regulation of tissue remodeling | biological process | GO:0034103 | 58 | 16 | 16441 | 2455 |
IL15,INPP5D,UBASH3B,TP53,P2RX7,IL18,ABR,SPP1,CA2,CST3,BAX,SUCO,INPP4B,TMEM64,SYK,TMBIM1 |
| 9.220e-03 | -4.69 | proteoglycan biosynthetic process | biological process | GO:0030166 | 58 | 16 | 16441 | 2455 |
CHSY3,B3GALT6,XYLT1,PXYLP1,DSE,EXT2,FOXL1,CHPF,GLCE,HS6ST1,XYLT2,CSGALNACT1,CANT1,HS3ST3B1,NDST3,HS6ST3 |
| 9.230e-03 | -4.69 | Mitotic G1-G1/S phases | REACTOME pathways | R-HSA-453279 | 135 | 31 | 8202 | 1235 |
CCNE2,PSMB4,PSME2,MYBL2,PSMD7,CUL1,PSMD10,PSME1,PKMYT1,CCNB1,CDK1,PSMA4,PRIM1,TOP2A,CCND1,CDKN2C,RB1,WEE1,PCNA,PSMD1,CCNA2,RBL1,PSMD3,PSMC2,E2F1,CDKN1B,CKS1B,HDAC1,CDKN2D,PSMC1,PSMA5 |
| 9.250e-03 | -4.68 | SABATES_COLORECTAL_ADENOMA_UP | MSigDB lists | SABATES_COLORECTAL_ADENOMA_UP | 128 | 29 | 17758 | 2588 |
NFE2L3,KRT80,WDR72,KLK10,NQO1,S100A11,EPHX4,CCNO,NOTUM,GPSM2,DUSP4,ANLN,PHLDA1,S100A2,SRPX2,TRIM7,IRX3,TNS4,SLC6A6,GRHL1,NKD1,FABP6,DGAT2,SERPINB5,CDH3,IGFBP2,TACSTD2,ETV4,SP5 |
| 9.252e-03 | -4.68 | SAFFORD_T_LYMPHOCYTE_ANERGY | MSigDB lists | SAFFORD_T_LYMPHOCYTE_ANERGY | 85 | 21 | 17758 | 2588 |
MMD,NDRG1,FURIN,ISYNA1,DDR1,TNFRSF19,TNFSF9,CASP4,IER3,FYN,HLF,KCNK5,CSF1,S100A5,NR4A3,NR4A2,MYH14,MARCH2,F2R,JAK3,JARID2 |
| 9.252e-03 | -4.68 | KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | MSigDB lists | KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | 85 | 21 | 17758 | 2588 |
PLK1,AKT1,RPS6KA1,PIK3R1,PKMYT1,CCNB1,PRKACA,CDC25C,CDK1,RPS6KA2,CCNA2,IGF1R,CCNB3,PIK3CA,MAPK11,BUB1,MAPK13,PIK3CD,CCNB2,RPS6KA3,MAPK12 |
| 9.264e-03 | -4.68 | IRS4 (insulin receptor substrate 4) | protein interactions | 8471 | 93 | 24 | 16036 | 2547 |
BIN1,PINK1,LGR4,CTSB,CUL4B,PIK3R1,TP53,CUL1,ERBB2,AURKB,SAV1,ILK,LGALS3BP,EGFR,VCP,MAGED2,RCN1,IGF1R,PTEN,P4HA2,PIK3CA,TUBG1,AURKA,HSPB1 |
| 9.265e-03 | -4.68 | PX | pfam domains | PF00787 | 48 | 14 | 16629 | 2504 |
SNX8,SNX13,SNX18,SGK3,SNX16,PLD2,PIK3C2B,PLD1,SNX9,SNX10,PXDC1,SNX12,SNX30,SNX7 |
| 9.273e-03 | -4.68 | developmental growth | biological process | GO:0048589 | 328 | 65 | 16441 | 2455 |
EMX1,GRHL2,ADD1,IQGAP1,WDTC1,TP53,GATA3,PLAC1,CCNB1,STIL,NOV,TGFBR3,SMO,PDE4D,TFAP2C,KLK6,PRKCQ,ICMT,ALCAM,ULK2,FZD7,GINS4,AREG,PTK7,SLC9A6,WWTR1,EFNA5,APBA2,COBL,PRKAR1A,KLF2,CDKN1C,TMTC3,CCM2,SOX9,LRP4,TEC,APBA1,NRP2,PTEN,FLRT3,ADAM15,ERCC2,WNT3A,SLC12A2,SPRY2,EPB41L5,WNT10B,SALL4,FMN1,BCL9,ASPM,RC3H2,C3orf58,MAP1B,GNAS,NCOA3,TIMP3,FGFR2,CSF1,AURKA,ZMIZ1,SEMA3A,NCAPG2,RARG |
| 9.280e-03 | -4.68 | ZBTB16 (zinc finger and BTB domain containing 16) | protein interactions | 7704 | 123 | 30 | 16036 | 2547 |
MX1,MAP3K3,CASP3,CCDC109B,LMTK3,CEP70,PLSCR1,NR3C1,TRAF2,GNE,TP53,FHL2,HDAC6,FAM101B,CDK1,SMN1,SH2D4A,HDAC9,RB1,PAFAH1B3,TIMP1,GATA2,ATP7B,FCHO1,DNM2,BCL6,HDAC1,CD81,CBX5,SPRY2 |
| 9.280e-03 | -4.68 | MAP3K7 (mitogen-activated protein kinase kinase kinase 7) | protein interactions | 6885 | 123 | 30 | 16036 | 2547 |
MAP3K3,TRIM8,TAOK2,PINK1,RIPK2,TRIM5,TAB3,TRAF2,PRKAA1,XIAP,STRADB,PRKCQ,TGFBR1,PELI3,FOS,MAPK8IP1,BCL10,SOCS3,CARD8,IRAK1,SIVA1,NFKBIA,NOD2,IL17RA,MAP3K7,MAP3K5,HSPB1,TRAF5,SYK,FBXW5 |
| 9.285e-03 | -4.68 | erythrocyte homeostasis | biological process | GO:0034101 | 78 | 20 | 16441 | 2455 |
KLF2,CASP3,DYRK3,ADD1,EPAS1,THRA,DMTN,NFE2L1,GATA3,SLC11A2,FECH,SFXN1,RB1,TGFBR3,AXL,BCL6,PTBP3,ERCC2,JAK3,SLC25A38 |
| 9.291e-03 | -4.68 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN | 167 | 36 | 17758 | 2588 |
DYRK3,IL15RA,PARP14,AASS,CRYM,HERC5,SAMD9,HERC6,TNFRSF19,PGAP1,DUSP5,MXD1,SYTL2,TMCC3,OTUD1,FAM111A,IFIT1,OAS3,AMOTL2,ARAP2,PLSCR1,PAPD7,ZSCAN12,COL7A1,IFIT3,C19orf66,NLRC5,IRF7,NRG1,HS3ST3B1,CMPK2,FBXO27,GLCCI1,RARG,CSRP2,IRF1 |
| 9.296e-03 | -4.68 | response to ATP | biological process | GO:0033198 | 30 | 10 | 16441 | 2455 |
P2RX4,PTGS2,SOD1,HSP90B1,SSH1,PTEN,DGKQ,P2RX7,SELL,TRPC3 |
| 9.296e-03 | -4.68 | microtubule anchoring | biological process | GO:0034453 | 30 | 10 | 16441 | 2455 |
GCC2,RB1,CAMSAP3,FOPNL,NDC80,CENPE,AURKB,SGOL1,DAG1,NIN |
| 9.308e-03 | -4.68 | GSE3982_CTRL_VS_LPS_48H_DC_UP | MSigDB lists | GSE3982_CTRL_VS_LPS_48H_DC_UP | 184 | 39 | 17758 | 2588 |
DLGAP5,JRKL,CHCHD7,ATP9A,CTDSPL,ARL4C,MERTK,HDAC9,MAGOHB,CCDC92,PAK6,SNX13,KCTD15,TGFBR3,FUT2,CTSC,PAPSS1,OPN3,SORL1,AHCY,ALDH7A1,FAR2,CLIP2,SLC16A5,RBMS2,SNED1,HMGN5,CORO2A,PBK,FHL2,GLO1,RAB38,DNAJC10,FYN,PRDX3,CORO1C,PLA2G15,PER3,CPPED1 |
| 9.308e-03 | -4.68 | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | 184 | 39 | 17758 | 2588 |
MAN2B2,SLC35D2,ZNF395,ST14,HEBP1,HERC5,PSME1,H1FX,CCDC92,TRANK1,GALNS,IL17RA,KLF9,OAS3,PHKA2,NFKB2,TIAM1,CKAP4,SMAGP,PIGC,TGIF1,PDGFC,ADCK3,NPC2,EPHA1,SRSF5,IFIT3,PLEKHB1,NMT2,STK17A,MAGED2,TAPBP,PEX5,RAB11FIP2,SPINT2,IRF7,IFI6,PPP2R2D,PCSK5 |
| 9.320e-03 | -4.68 | regulation of lymphocyte activation | biological process | GO:0051249 | 369 | 72 | 16441 | 2455 |
LAMP1,CASP3,IL15,INPP5D,GATA3,ERBB2,IL27RA,IL18,EGR3,CD274,FLT3,TNFSF9,CD46,CTNNB1,IL6ST,BCL6,PIK3CA,DLG1,SLC39A10,FLOT2,RASGRP1,SOD1,CD55,RIPK2,AKT1,LGALS8,ITCH,PRKCQ,CD40,IRS2,FYN,STAT6,AXL,NOD2,PRKAR1A,LGALS3,DHPS,TRAF2,HLA-E,PKN1,MERTK,EFNB1,HLA-A,RAC2,PAK2,FBXO7,IGFBP2,C10orf54,WNT3A,RAG1,MAP3K7,SYK,MSH6,SOCS5,HES1,RHOA,PIK3R1,WHSC1,PDE5A,YES1,CD83,BCL10,SOX13,FAS,BANK1,PPP2R3C,ICOSLG,CD81,JAK3,NDFIP1,AHR,IRF1 |
| 9.327e-03 | -4.67 | cortical actin cytoskeleton | cellular component | GO:0030864 | 59 | 16 | 17570 | 2579 |
LASP1,NF2,DSTN,FLOT1,PLS1,ANLN,SPTB,CAPN2,PLEKHH2,SCNN1A,CDH1,LLGL2,CALD1,SPTBN5,FLOT2,SHROOM2 |
| 9.329e-03 | -4.67 | regulation of leukocyte activation | biological process | GO:0002694 | 428 | 82 | 16441 | 2455 |
LAMP1,CASP3,IL15,INPP5D,GATA3,ERBB2,IL27RA,IL18,EGR3,CD274,SLC7A2,FLT3,TNFSF9,CD46,CTNNB1,IL6ST,IL31RA,BCL6,PIK3CA,DLG1,SLC39A10,PTPRE,FLOT2,RASGRP1,SOD1,CD55,RIPK2,AKT1,LGALS8,ITCH,PRKCQ,CD40,ABR,IRS2,FYN,AXL,STAT6,NOD2,F2RL1,PRKAR1A,LGALS3,DHPS,TRAF2,HLA-E,PKN1,MERTK,EFNB1,HLA-A,RAC2,FBXO7,PAK2,IGFBP2,C10orf54,WNT3A,RAG1,MAP3K7,SYK,MSH6,SOCS5,HES1,RHOA,PLSCR1,PIK3R1,VAMP3,PDE5A,WHSC1,YES1,FAS,CD83,BCL10,SOX13,BANK1,PVRL2,NR4A3,PPP2R3C,GPER1,ICOSLG,CD81,NDFIP1,JAK3,AHR,IRF1 |
| 9.342e-03 | -4.67 | Apoptosis | KEGG pathways | hsa04210 | 85 | 22 | 6908 | 1076 |
CASP3,AKT1,TRAF2,PIK3R1,CASP9,TP53,XIAP,PRKAR2B,BCL2L1,PRKACA,FAS,IL1R1,CAPN2,CASP7,IRAK1,NFKBIA,PIK3CA,BAX,PIK3CD,IL1RAP,CAPN1,PRKAR1A |
| 9.342e-03 | -4.67 | Apoptosis | KEGG pathways | ko04210 | 85 | 22 | 6908 | 1076 |
CASP3,AKT1,TRAF2,PIK3R1,CASP9,TP53,XIAP,PRKAR2B,BCL2L1,PRKACA,FAS,IL1R1,CAPN2,CASP7,IRAK1,NFKBIA,PIK3CA,BAX,PIK3CD,IL1RAP,CAPN1,PRKAR1A |
| 9.349e-03 | -4.67 | positive regulation of nucleobase-containing compound metabolic process | biological process | GO:0045935 | 1697 | 287 | 16441 | 2455 |
ACVR1,TRIM24,LGR4,TRIM5,HEXB,RET,GATA3,MORF4L2,CAMK1D,CCNB1,TP73,NPM2,CALM2,HELZ2,ZFP36,IL31RA,FOSB,DNM2,IRF2,NEK4,SMARCA2,TNIP1,TFAP2C,AURKB,LDB2,SAV1,ARF4,AHRR,AREG,TBX1,NOD2,HDAC1,RNASEL,TRAF5,F2RL1,E2F8,HOXC13,DDX58,KLF2,CDKN1C,ITGA6,SOX9,PRKAA1,PSIP1,LMNA,MECOM,ELF3,TFAP4,CALR,CYR61,NEK2,MYDGF,MAPK7,NUP85,GPR161,SALL4,STAT4,CALM1,FHL2,MYBL2,WHSC1,CALCRL,ELK1,ILK,TP53INP2,KDM3A,NFIB,NCOA3,SERTAD2,ETS2,SETD3,PIAS2,NR4A2,RPS6KA3,TMEM173,IRF1,ARMCX3,GRHL2,THRA,RPS6KA1,CCNA2,CDH1,SP100,DAB2IP,ETV4,MED30,PSRC1,RIPK2,FZD4,FOXJ2,PRKCQ,PYGO1,GTF2A2,EBF2,FZD7,NFIX,WFS1,WWTR1,STAT1,KLF5,NRG1,ARNT,ATMIN,TNRC6C,NKX3-1,CKAP2,TRAF2,PBX3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,E2F7,IRAK1,PTEN,MCF2L,CST3,BAX,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,MSH6,PDGFC,CASK,PLSCR1,BCL9,TEF,PIK3R1,GRIN1,YES1,FOS,ABLIM2,TXK,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,ACVRL1,NR1D2,NR4A3,GPER1,HMGA1,FZD5,OSR1,CD81,USF2,SHOX2,FOXA1,USP16,RGMA,CCNC,EPAS1,AGRN,CNOT8,PDGFB,TFAP2E,EPCAM,HSF2,PCNA,CTNNB1,GRHL1,NPNT,PSMC2,ELF5,MITF,ASH2L,ARNT2,MYBL1,ZNF462,THRB,PCGF5,TRIM8,CITED4,ASXL1,NFE2L1,EAF2,VCP,EDNRA,KDM4D,SEC14L2,MDK,KLF12,MAFF,PSMC1,NR2C2,PRKAA2,RUNX2,PPP1R12A,ETV5,CALM3,BMP2,RB1,DAZAP1,IGF1R,GATA2,PRKCI,EBF4,MDFIC,WNT3A,ELK3,RGMB,EGFR,GNAS,ONECUT1,NUDT16,INSR,PLPP3,NFKBIA,NLRC5,RARG,TOB1,RAD21,DRD1,KLF7,PAX6,FOXM1,TP53,P2RX7,ERBB2,CCNL1,OSR2,LPIN3,PDGFA,SS18,LMO4,SMO,TWIST1,ZBTB49,NOTCH3,NFKB2,F2R,DVL2,CTH,SIRT1,TIMP2,AKT1,TCEB2,SERTAD3,CD40,JADE1,HSF4,RBL1,STAT6,IRF7,AKNA,ABCA1,GLIS3,ANXA3,PINK1,TAB3,ARHGEF11,GNAL,HMGN3,TGFBR1,PARM1,GBX2,TOP2A,IRF2BPL,BMP7,TOX2,GTF2F2,TFAP2A,BRD7,TRIM21,NFE2L3,HES1,DCAF6,HMGN5,WNT10B,NR3C1,NR4A1,RGCC,PPARA,MAML2,RUNX3,BCL10,E2F1,ARRB1,PKD2,ZMIZ1,SOX8,AHR |
| 9.395e-03 | -4.67 | regulation of protein localization to nucleus | biological process | GO:1900180 | 191 | 41 | 16441 | 2455 |
DDX58,TXN,NF2,NFKBIE,THRA,RAB23,PSMD10,TGFBR1,IL18,APC2,IL18R1,LMNA,NOV,CDH1,DACT1,BMP7,CABP1,SMO,DAB2IP,MDFIC,WNT3A,MAPK7,MDFI,CHP1,SIRT1,RHOA,TRIM8,AKT1,PIK3R1,LITAF,PRKCQ,CDK1,EGFR,FZD7,PTGS2,FYN,NFKBIA,WWTR1,PKD2,PKIA,TMEM173 |
| 9.427e-03 | -4.66 | skin-lower_leg-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-lower_leg-carcinoma-squamous_cell_carcinoma | 22 | 8 | 17775 | 2585 |
FGFR2,RET,PIK3CA,TP53,ERBB2,NOTCH2,FLT3,EGFR |
| 9.427e-03 | -4.66 | bronchus | COSMIC cancer mutations | bronchus | 22 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 9.427e-03 | -4.66 | skin-arm-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-arm-carcinoma-squamous_cell_carcinoma | 22 | 8 | 17775 | 2585 |
FGFR2,RET,PIK3CA,TP53,ERBB2,NOTCH2,FLT3,EGFR |
| 9.485e-03 | -4.66 | phospholipid scramblase activity | molecular function | GO:0017128 | 10 | 5 | 16491 | 2452 |
PLSCR4,ANO9,PLSCR1,ANO4,ANO6 |
| 9.485e-03 | -4.66 | transforming growth factor beta-activated receptor activity | molecular function | GO:0005024 | 10 | 5 | 16491 | 2452 |
LTBP1,TGFBR1,ACVR1,TGFBR3,ACVRL1 |
| 9.492e-03 | -4.66 | TPR | smart domains | SM00028 | 93 | 24 | 9131 | 1455 |
TTC8,TMTC1,ST13,LONRF3,TMTC3,DNAJC3,KLC2,TTC7A,GPSM2,TMTC2,IFIT3,NPHP3,TANC1,UNC45B,SPAG1,TTC21B,PEX5,NOXA1,TTC12,KLC3,CABIN1,IFIT1,TTC9,TANC2 |
| 9.498e-03 | -4.66 | ST_B_CELL_ANTIGEN_RECEPTOR | MSigDB lists | ST_B_CELL_ANTIGEN_RECEPTOR | 40 | 12 | 17758 | 2588 |
NFKBIE,AKT1,NFKBIA,PLCG2,PIK3R1,PIK3CA,PIK3CD,ITPKA,NFKB2,NFAT5,DAG1,SYK |
| 9.501e-03 | -4.66 | single-organism intracellular transport | biological process | GO:1902582 | 1200 | 208 | 16441 | 2455 |
LAMP1,ACACB,FAF2,IBTK,CPT2,SLC25A13,KLC2,TAP1,TRAPPC8,TGOLN2,HDAC6,SNX9,SLC8B1,RIC1,PICK1,ZFYVE16,NAPG,AP1M2,ARL1,LMAN2L,STEAP2,DNM2,SNX16,RP2,TINAGL1,PIK3CD,TFG,TRAM1,S100A13,RASGRP1,VPS11,SOD1,UXT,BNIP3L,ARFRP1,KIF13A,ICMT,MCFD2,VCP,OPTN,TBC1D17,WIPI1,AREG,GNPTAB,ATP7B,TRAF3IP1,KPNA2,PRKAA2,PEX6,SEC61G,RAB6A,SLC1A3,APBA1,FAM21C,LMNA,SSX2IP,ATG4A,CALR,DOPEY2,SNX18,GATA2,ATP5H,RPL39,KIF13B,FBXO7,PRKCI,SRP54,SORL1,PIKFYVE,NUP85,PPP6R1,TMED2,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,ERO1A,STRADB,NPC2,SRSF5,ZDHHC3,RHOB,TSC1,AP1AR,SCARB2,PRKAG2,TIMM8A,HTT,ZDHHC20,WDR19,NFKBIA,ITPR1,RAB31,ZDHHC7,LTBP2,NDE1,HOOK1,JAK3,NRBP1,TOB1,DRD1,EHD1,KIF3C,MTM1,SLC25A24,CCDC109B,UPF3B,TP53,P2RX7,FTH1,BCL2L1,MICALL2,EMP2,BCAP31,ZFYVE9,TTC21B,KIF14,ZDHHC12,PLCG2,BCL6,ZDHHC23,TNPO2,RPN2,LMAN1,F2R,TBC1D10B,CHP1,ATG4D,PPIF,SNX8,SEC23A,SEC61B,AKT1,COG2,VPS4B,KIF1C,AP5M1,ATP1B1,RAB38,ITPR3,DAG1,TAPBP,PEX5,STX10,DDOST,PEX2,CHMP4B,RAB29,SPTBN5,RPL22,SLC25A30,ABCA1,COPG1,HSP90B1,TAOK2,SORT1,TRAPPC10,CD63,ATP9A,SH3D19,ARL4C,PDIA3,CTSZ,IFT27,AIP,VPS26A,HMGXB4,ZDHHC21,M6PR,KIF5B,ANK1,ADORA1,CTSC,PPP1R10,FAM160A2,BAX,KLC3,ABCD1,SYK,RPGR,MYO5A,HES1,LCA5,ZC3H11A,PIK3R1,MRS2,VAMP3,PRICKLE1,COL7A1,RAB3IP,FAM109A,BBS2,MAP1B,RGPD5,LDLRAP1,RPL12,SERPINA1,NR4A3,ARRB1,SSNA1,PKD2,MCUR1,SPCS3,ARSB,NDFIP1,SRSF9,ABCG1 |
| 9.507e-03 | -4.66 | V$AP2GAMMA_01 | MSigDB lists | V$AP2GAMMA_01 | 236 | 48 | 17758 | 2588 |
CCDC24,IER5L,SCN5A,GRHL2,CPEB4,CERCAM,SOX9,PKN1,PDGFB,DENND2D,TSPAN17,NFAT5,SIX4,MECOM,NEO1,APLP2,RNF220,ZNF687,ARTN,ZNRF2,ATP5H,LMO4,LHX6,TRPC1,NOTCH3,ETV4,DGKG,TSPAN33,KCNJ12,CXXC5,NR3C1,CBX6,SRRM3,MAP3K6,NFIB,SP4,MAP1B,CD83,PITX2,DGCR2,KLF12,PTK7,MAP3K11,NXPH4,CTSA,RARG,JARID2,NR2C2 |
| 9.510e-03 | -4.66 | SMID_BREAST_CANCER_LUMINAL_B_DN | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_B_DN | 524 | 96 | 17758 | 2588 |
PLA2G4A,LTBP1,UGT8,TRIM2,KLK10,PAX6,PAPSS2,GALNT12,NDRG1,TAP1,SOD2,NDRG2,IL27RA,MRAS,CYP39A1,NOV,MUC16,SRPX,CTGF,LMO4,ALDH1A3,ELF5,CDH3,PIK3CD,LAMP3,CYP1B1,CAPN6,SAT1,PTGER4,CR2,KLK6,FZD7,PLCH1,PTGS2,FYN,PTK7,HOXA9,MYLK,WWTR1,KLF5,APBA2,RRAGD,BIN1,ANXA3,COL9A3,CDKN1C,SERPINE2,JRKL,CKAP2,ITGA6,CALB2,RAB23,ARL4C,SELL,NES,GSTP1,FBLN1,S100A2,LBR,ICAM1,RAC2,ADD3,CYR61,CTSC,CALD1,KCNK5,KCNN4,AIM1,ITM2C,GPR161,CYP26B1,KLK5,FBLN5,BTN3A2,RUNX3,LEPR,NFIB,EGFR,MAP1B,FAS,RASGRP2,GALNT3,BANK1,PROM1,RND3,ITGA7,CSGALNACT1,DTX4,PGRMC1,SERPINB5,KLK7,FHL1,GEM,SHOX2,L1CAM,CSRP2 |
| 9.536e-03 | -4.65 | LIM_DOMAIN_1 | prosite domains | PS00478 | 72 | 19 | 11866 | 1802 |
LMO7,FBLIM1,LASP1,CRIP2,LMCD1,FHL2,PRICKLE1,MICALL2,ABLIM2,ZYX,PDLIM3,LIMK1,PRICKLE4,LMO4,PRICKLE3,LHX6,LIMCH1,FHL1,CSRP2 |
| 9.536e-03 | -4.65 | LIM_DOMAIN_2 | prosite domains | PS50023 | 72 | 19 | 11866 | 1802 |
LMO7,LASP1,FBLIM1,CRIP2,FHL2,LMCD1,PRICKLE1,MICALL2,ABLIM2,ZYX,PDLIM3,PRICKLE3,LMO4,LIMK1,PRICKLE4,LHX6,LIMCH1,FHL1,CSRP2 |
| 9.547e-03 | -4.65 | CAMK2A (calcium/calmodulin-dependent protein kinase II alpha) | protein interactions | 815 | 69 | 19 | 16036 | 2547 |
AKT1,PTTG1,GRIN1,CDCA8,CALM3,TANC1,ETS1,ITGA2B,EGFR,CDK5R1,RAD23A,DAPK2,PLCG1,CAMK2N2,DLG1,ITPKA,ZMYM1,DLG3,CAMK2G |
| 9.547e-03 | -4.65 | DAZARD_UV_RESPONSE_CLUSTER_G4 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G4 | 22 | 8 | 17758 | 2588 |
CDKN1C,TUBB4B,ZFP36,CAPNS1,SULT2B1,H1FX,DUSP1,TUBA4A |
| 9.547e-03 | -4.65 | BIOCARTA_CHEMICAL_PATHWAY | MSigDB lists | BIOCARTA_CHEMICAL_PATHWAY | 22 | 8 | 17758 | 2588 |
CASP3,CASP7,AKT1,CASP9,STAT1,TP53,BAX,BCL2L1 |
| 9.547e-03 | -4.65 | RESPONSE_TO_DRUG | MSigDB lists | RESPONSE_TO_DRUG | 22 | 8 | 17758 | 2588 |
BCAR3,GCLM,SOD1,PAPD7,ABCG2,ABCB1,ABCA2,ABCC1 |
| 9.547e-03 | -4.65 | EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 22 | 8 | 17758 | 2588 |
REPS2,SHC3,EPS8,ERBB2IP,CBL,BCAR1,GAB1,EGFR |
| 9.547e-03 | -4.65 | BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER | MSigDB lists | BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER | 22 | 8 | 17758 | 2588 |
IRS2,CTNNB1,DACT1,ERBB2,TGFBR1,ERBB3,FZD7,EGFR |
| 9.547e-03 | -4.65 | KANG_FLUOROURACIL_RESISTANCE_UP | MSigDB lists | KANG_FLUOROURACIL_RESISTANCE_UP | 22 | 8 | 17758 | 2588 |
MDK,DDB2,LZTFL1,NOV,BTG3,NQO1,OSBPL3,IGFBP2 |
| 9.548e-03 | -4.65 | regulation of cell projection assembly | biological process | GO:0060491 | 147 | 33 | 16441 | 2455 |
SSH1,AGRN,TBC1D1,P2RX7,TGFBR1,NCKAP1,MNS1,ICAM1,EPS8L2,RAC2,DNM2,ATP8B1,TACSTD2,ESPN,TBC1D10B,SSH3,DMTN,PRKCQ,DPYSL3,ARHGAP24,TBC1D17,HTT,CORO1C,ARAP1,FAM110C,KLF5,PLD1,ARF6,ARPC2,RAP1GAP,F2RL1,COBL,ADAMTS16 |
| 9.549e-03 | -4.65 | CROMER_METASTASIS_DN | MSigDB lists | CROMER_METASTASIS_DN | 80 | 20 | 17758 | 2588 |
DDB2,PRODH,KLK10,EPAS1,S100A11,FXYD3,SDC4,CUL1,GSTP1,CARD10,LMNA,ITGA3,RAB31,BMP1,SERPINB5,KLF5,MAST4,HSPA2,TUBA4A,IGSF3 |
| 9.549e-03 | -4.65 | CTCNANGTGNY_UNKNOWN | MSigDB lists | CTCNANGTGNY_UNKNOWN | 80 | 20 | 17758 | 2588 |
SPRED1,TAF5,SLC2A4,REPS2,TEF,RUNX3,FXR2,BAHD1,CYFIP2,PRR7,ABR,H1FX,FOXP2,ARHGEF19,CGREF1,C1orf21,CITED2,SHOX2,ABCA1,RPS6KA3 |
| 9.549e-03 | -4.65 | PID_MET_PATHWAY | MSigDB lists | PID_MET_PATHWAY | 80 | 20 | 17758 | 2588 |
INPPL1,RHOA,AKT1,INPP5D,PIK3R1,CBL,BCAR1,ETS1,RANBP9,SH3KBP1,PLCG1,PTPRJ,CDH1,CTNNB1,PAK2,PIK3CA,PRKCI,ARF6,GAB1,ARHGEF4 |
| 9.552e-03 | -4.65 | haemangiopericytic | COSMIC cancer mutations | haemangiopericytic | 96 | 23 | 17775 | 2585 |
NF2,DEPDC1,ACVR1C,GGA1,TMTC3,TP53,ATP8B3,KIF2C,IDH1,EGFR,IRS2,CDKN2C,PLCH1,SS18,TRANK1,NAB2,TUBGCP6,SLC4A3,ACADM,MOXD1,MGAT5,NDST3,EHD1 |
| 9.552e-03 | -4.65 | meninges-meningioma-haemangiopericytic | COSMIC cancer mutations | meninges-meningioma-haemangiopericytic | 96 | 23 | 17775 | 2585 |
NF2,DEPDC1,ACVR1C,GGA1,TMTC3,TP53,ATP8B3,KIF2C,IDH1,EGFR,IRS2,CDKN2C,PLCH1,SS18,TRANK1,NAB2,TUBGCP6,SLC4A3,ACADM,MOXD1,MGAT5,NDST3,EHD1 |
| 9.565e-03 | -4.65 | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | 190 | 40 | 17758 | 2588 |
EPAS1,SEC61G,SLC25A13,MCTP2,PTTG1,EFHD2,BCL2L1,QSOX2,BMP2K,UHRF1BP1L,IER3,CD109,SS18,RAC2,KCNN4,IMPAD1,PDE4D,BTBD3,SYTL3,GM2A,FAH,C9orf9,GCA,CCBL2,ERP44,CMTM7,SLCO4A1,BOLA3,PPP2R5A,KIAA0141,UEVLD,WIPI1,DBI,NR4A3,NOD2,RCAN2,ITGAV,GEM,ZMIZ1,CPPED1 |
| 9.565e-03 | -4.65 | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP | MSigDB lists | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP | 190 | 40 | 17758 | 2588 |
LTBP1,NFKBIE,ADD1,ZCCHC24,CTSB,HOXB2,H1FX,PDIA4,CDS1,SLC25A36,BTG3,CARD8,KIAA1107,CTNNB1,KIF14,FAM20B,KIAA0319,PRKCI,TUBG1,ACTA2,OSTF1,ACSL4,CACNA1D,ARL4D,CTH,CDYL,ACO1,BNIP3L,UBAC1,GLO1,PSMA4,GLCE,SERTAD2,SCG2,STK39,ATP1B3,PLOD3,SHOX2,STARD13,SHROOM2 |
| 9.565e-03 | -4.65 | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDM_DN | 190 | 40 | 17758 | 2588 |
PAPSS2,GNPDA1,ARHGEF7,TSC22D3,INPP5D,MRAS,SLC7A2,SEPT4,CALR,ADD3,REEP1,OPN3,IL17RA,SNX16,ERBB3,RCAN3,TMEM8A,MYLIP,CERS2,PAQR7,ERMP1,PQLC3,AMFR,LPGAT1,ITCH,STAT4,SPATA13,UTRN,PIM3,ATP1B1,MCFD2,TXNDC11,ZDHHC3,ULK2,FNTA,UAP1,DONSON,LRRK1,CEP41,MAFF |
| 9.565e-03 | -4.65 | GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP | 190 | 40 | 17758 | 2588 |
TRIM24,HJURP,BLVRB,NDC80,GMPR,COL18A1,SLC36A4,NENF,KIAA1147,KIAA0895,PIK3AP1,TSPAN6,KIF14,PPP1R16A,REEP1,TUBG1,RPN2,MANF,FLOT2,PPP6R1,MYO5A,MCTP1,MOSPD2,CCDC34,KIF20B,ANLN,RANBP9,GINS4,DHDH,FNTA,MFSD2A,PEX2,AGBL5,TRIM45,HDAC1,PKD2,MDH1,ALG2,NDE1,FBXO27 |
| 9.565e-03 | -4.65 | GSE17721_0.5H_VS_8H_CPG_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_8H_CPG_BMDM_DN | 190 | 40 | 17758 | 2588 |
ENO2,AGRN,IL15,PARP14,TBC1D1,HLA-E,EPHA4,TAP1,PSMD10,F11R,MPP5,PLA2G16,ICAM1,WDFY1,GRHL1,LMO4,FAM20B,TNPO2,TFG,GFPT1,ENPP4,MOB4,UFD1L,ARAP2,ELK3,TESK1,LAP3,DENND1B,USP18,LYRM1,AK4,RAD17,ASB13,TBX18,ABCB1,CHMP4B,PPP2R3C,AKNA,RGS14,ABCA1 |
| 9.565e-03 | -4.65 | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_DN | MSigDB lists | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_DN | 190 | 40 | 17758 | 2588 |
ST13,PPM1J,POC1B,SLC2A8,HEBP1,RASSF7,ERCC6L,DHRS3,INPP5E,KCTD15,UBE2T,IL6ST,BDH1,OPN3,PLEKHF1,ZNF692,AK3,LGMN,RCAN3,DLG3,CNPY3,TIMP2,FZD4,STRADB,CCDC34,ZSCAN12,TNFAIP8L1,ANLN,PDIK1L,BORA,TRUB1,GLCE,DHX32,FASTKD1,WDR11,SLC35B3,CORO1C,CGREF1,SSNA1,CBX5 |
| 9.565e-03 | -4.65 | GSE17721_CTRL_VS_LPS_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_24H_BMDM_UP | 190 | 40 | 17758 | 2588 |
TPRN,GNPDA1,MRPS15,ELOVL7,HABP4,FAM134A,ABCG2,ERCC6L,GMPR,TESK2,IL18,COL4A5,LTBP3,XPR1,CDKN2C,FAM111A,ELMO2,PPP4R1,IQGAP3,CASD1,MYO5A,MED22,KIF20A,GUSB,LGALS8,LPGAT1,KLK6,ANLN,SESN1,DAG1,STEAP1,TCN2,INSR,RND3,NR1D2,ARRB1,KLF5,PLD1,PDXK,GLCCI1 |
| 9.565e-03 | -4.65 | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_DN | 190 | 40 | 17758 | 2588 |
GRN,LASP1,HECA,BMF,ARAP3,JKAMP,TSC22D3,DCAF7,FAM78A,DPP8,PCBP1,C9orf69,ZNF432,CXCL16,RNF220,UBE2Q2,FBXO7,BRI3,CTDSP2,FAM134C,TBC1D10B,ORAI2,BAG4,TAF5,TMEM43,TACC1,PLEKHO1,UBAC1,TNFAIP8L1,CBL,KDM3A,DDX23,GDE1,SH2D3C,ZDHHC7,CAB39,SLC31A2,NRBP1,SRSF9,CTDSP1 |
| 9.565e-03 | -4.65 | GSE13306_RA_VS_UNTREATED_TCONV_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_TCONV_DN | 190 | 40 | 17758 | 2588 |
PARP12,CHCHD7,DAP,CYB561,FTH1,IL18R1,LYPD5,KIAA0895,ADD3,DNAH6,GTF2F2,TFAP2A,KCNS3,CDH3,WWP1,SEMA3G,OAS3,SLC16A5,ZNF462,CRB3,IFITM3,FZD4,ACBD3,LITAF,KCTD20,MTRF1L,SLC11A2,RAB38,EBF2,MAP1B,DCAF10,ALDH5A1,NGFRAP1,DCK,FGF18,BMP1,RCAN2,MDH1,F2RL1,EHD1 |
| 9.565e-03 | -4.65 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 190 | 40 | 17758 | 2588 |
BIN1,SLC25A24,CCDC109B,PPP1R12A,INPP5D,CNOT8,BLCAP,NOTCH2,SNN,DPP8,TIPRL,SGPL1,PDCD10,FRY,CD22,PAK2,CAPG,SORL1,RFX5,PIK3CD,PIKFYVE,SNX10,CDKN2D,MYLIP,SYPL1,GCA,AGPS,CR2,SRSF5,POLD3,MYL12A,RASGRP2,FYN,SWAP70,STK38,STAT6,CLMN,TBC1D4,MYL12B,PHC1 |
| 9.565e-03 | -4.65 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN | 190 | 40 | 17758 | 2588 |
NUDT6,DHPS,PTTG1,CDCA3,GSTP1,SLC25A43,ECI1,CORO1B,CENPJ,OSBPL3,BDH1,PRC1,CKS1B,ECI2,EGLN3,FAR2,C12orf75,APOBEC3G,IGSF3,FAH,SEPHS1,NFE2L3,TDP1,PSRC1,CTNNAL1,C1GALT1C1,WHSC1,CCDC34,PIF1,RNPEP,CDC25C,PRIM1,PRDX4,LRRC42,FAM83D,AURKA,GLB1,MRPS28,ATP1B3,ARF6 |
| 9.565e-03 | -4.65 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN | 190 | 40 | 17758 | 2588 |
SLC25A24,TNRC6C,LGALS3,TRAPPC10,P2RX7,EFHD2,CAMK1D,DHRS3,DENND2D,RASSF8,SLC25A45,RNF220,TGFBR3,FAM160A2,RGS3,TOX2,BCL6,CD9,FAM102A,TSPAN13,GCNT1,SMARCA2,PLSCR1,STAU2,PANK1,RNF11,CAPNS1,TCF7,CDK5R1,GPLD1,GNPTAB,LRIG1,APPL2,CSGALNACT1,PGM2L1,SERPINB6,STK39,TTC39C,NRBP1,PPP2R2D |
| 9.568e-03 | -4.65 | LYSASSOCTDMP | prints domains | PR00336 | 4 | 3 | 4759 | 661 |
LAMP2,LAMP1,LAMP3 |
| 9.568e-03 | -4.65 | P38MAPKINASE | prints domains | PR01773 | 4 | 3 | 4759 | 661 |
MAPK13,MAPK11,MAPK12 |
| 9.574e-03 | -4.65 | PDGFRA (platelet-derived growth factor receptor, alpha polypeptide) | protein interactions | 5156 | 37 | 12 | 16036 | 2547 |
PDGFA,PLCG1,PDGFC,JAK1,PTEN,PIK3R1,STAT1,ITGAV,CBL,PDGFB,ULBP2,EGFR |
| 9.574e-03 | -4.65 | ATP1B4 (ATPase, Na+/K+ transporting, beta 4 polypeptide) | protein interactions | 23439 | 37 | 12 | 16036 | 2547 |
TGFBR3,PTK7,ITGA7,GLB1L2,JAG2,POMT1,TMEM8A,PTGFRN,PGAP1,KIAA1161,NXPE3,HLA-A |
| 9.575e-03 | -4.65 | XBP1(S) activates chaperone genes | REACTOME pathways | R-HSA-381038 | 53 | 15 | 8202 | 1235 |
GFPT1,SEC61B,ADD1,WIPI1,SEC61G,WFS1,DNAJC3,PDIA5,DNAJB11,KDELR3,MYDGF,PDIA6,CTDSP2,DNAJB9,LMNA |
| 9.591e-03 | -4.65 | TRANSPORT | MSigDB lists | TRANSPORT | 785 | 138 | 17758 | 2588 |
SLC25A13,ARFGEF1,SYTL4,BAIAP3,CACNB4,SLC20A1,BARD1,ERP29,PICK1,ABCD4,ZFYVE16,NAPG,AP1M2,TM9SF2,STIM1,LMAN2L,SLC46A1,SLC44A1,STEAP2,KCNS3,ABCA2,TRPC1,TINAGL1,TRAM1,UXT,ERP44,SLC17A5,ICMT,SLC25A5,TCN2,VCP,EDNRA,OPTN,KCNMB4,SLC25A4,KCNK1,ATP7B,KPNA2,ARF6,SLC31A2,SCN5A,LASP1,ARAP3,NFKBIE,PEX6,GGA1,FXYD3,ABCG2,SLC1A3,APBA1,PGAP1,ATG4A,CALR,DOPEY2,GATA2,KCNN4,SLC16A6,KIF13B,PRKCI,SORL1,CACNA1D,KDELR1,ABCC1,MDFI,NAGPA,KCNJ12,KIF20A,STRADB,NPC2,RHOB,TSC1,SH3BP4,CTSA,LTBP2,PLIN3,TRPC3,NRBP1,SORBS1,KCNAB3,SLC2A4,SLC2A8,RALBP1,TP53,BCL2L1,SLC7A2,APPBP2,SYTL2,ZFYVE9,ATP6V0B,SCNN1A,CDH1,BCL6,LMAN1,SCN2A,F2R,ATG4D,SEC23A,AKT1,COG2,VPS4B,HTATIP2,KIF1C,SLC11A2,CBL,CORO1C,ABCA1,TRAPPC10,PDIA3,KCNC4,AIP,CKAP5,M6PR,KIF5B,ADORA1,PPP1R10,KCNK5,BAX,SLC35B4,SGK1,SLC44A2,CPLX1,TTPA,SLC16A5,RPGR,SLC35A1,TMX1,PPARA,VAMP3,AKAP3,MAPK8IP1,KLHL2,LDLRAP1,CTNS,ABCB1,PKD2,ATP6V1C1,ARSB,ABCG1 |
| 9.635e-03 | -4.64 | BROWNE_HCMV_INFECTION_14HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_DN | 283 | 56 | 17758 | 2588 |
KIAA1462,PAPSS2,ADD1,EPAS1,PEX6,ZCCHC24,CIT,RASA2,BLVRB,ASL,NDC80,RGS20,ERBB2,NOTCH2,GPSM2,SPTB,SIRPA,LMNA,APPBP2,MECOM,WWP2,APOBEC3B,ADD3,ST5,ITGA3,TAF1B,N4BP3,AIM1,BAX,ABCA2,CLDN4,IRF2,ERCC2,PIK3CD,RAB27B,SGCB,FAH,ABCC1,CYP1B1,HMMR,PIGC,PLAUR,PARP4,BTN3A2,DIAPH2,PDE5A,TP53I3,EGFR,FAS,KIAA0141,NR1D2,AXL,INPP4B,CENPE,ITPKA,CCNB2 |
| 9.639e-03 | -4.64 | YOSHIMURA_MAPK8_TARGETS_UP | MSigDB lists | YOSHIMURA_MAPK8_TARGETS_UP | 1274 | 215 | 17758 | 2588 |
RET,TAP1,FBXO2,IL18,PSME1,GALM,PLA2G16,CCNB1,CACNB4,PDGFB,SH3KBP1,GRM5,CALM2,EPCAM,WEE1,BTG3,PSMD1,CYP1A1,TGFBR3,DNAH6,SHC3,DLG1,FUT1,IRF2,TACSTD2,PIK3CD,ACOX2,PPP1CA,PTPRE,MGAT5,SOD1,ACVR1C,MTRF1L,EDNRA,CAMK2N2,GDE1,MAP2,DNM1L,KCNK1,LIMK1,ATP7B,MADD,ITPKA,APBA2,HSPB1,NRGN,F2RL1,MYL12B,DLAT,CDKN1C,HLA-E,HLA-F,TMEM55B,CALB2,STRN4,ASL,CALM3,COX6C,HPCAL4,DNPEP,CA2,IGF1R,EXOC8,MAP3K9,MSH2,PIM1,CNGA1,CACNA1D,C10orf54,PSMA5,MAPKAPK3,PTPRH,CALM1,PIP4K2C,CALCRL,PYGL,DPYSL4,GNA11,EGFR,CDK5R1,SOX13,PTPRF,IL1R1,GNAS,GABRD,SCARB2,FAAH,ITPR1,SLC4A3,EGFL7,CABIN1,STK39,TMEM120A,HOOK1,CBX5,SEMA3A,FBXW5,DRD1,KIF3C,SLC2A4,KCNAB3,HOXB7,NF2,FOXM1,TRIP10,RALBP1,INPP5D,GMPR,ERBB2,MRAS,SLC7A2,BCL2L1,EGR3,DDR1,IER3,CDS1,CCND1,SCNN1A,PLCG2,FABP6,PDE4D,EPB41L4B,ACSL4,SCN3A,GPX4,MYO5B,PPIF,PTPRU,PFKFB2,PTGER4,KIF1C,DNAJB14,DUSP4,ALCAM,SOCS3,IRS2,OSBPL2,IDE,ATP1A1,BFSP1,EFNA5,NRG1,ARNT,MAPK12,BIN1,NUDT6,CDH22,RBM24,HAL,GNAL,FLOT1,SELL,GABRG2,AES,GDF15,PLD2,JAG2,SPR,SEPP1,ETS1,EFNB1,LGALS3BP,SIRPA,SLC9A2,PTEN,CTSC,CDK16,BMP7,MCF2L,KCNK5,FDXR,BAX,IGFBP2,MXD3,ERBB3,CITED2,RAG1,GFI1,TTPA,SYK,ATP2B1,CAMK2G,DLGAP1,HES1,PCCB,OPLAH,RAB3B,PSMB4,NR3C1,PLAUR,TEF,PPARA,GRIN1,FURIN,FOS,BCAR1,LEPR,MAP1B,CD8A,RGS9,SERPINA1,ACADSB,SYT7,NAT1,NR4A3,SERPINB5,GRIN2D,HMGA1,WDR62,SHOX2,AHR,HIPK3,L1CAM,ACOT7,OCLN |
| 9.661e-03 | -4.64 | negative regulation of natural killer cell mediated immunity | biological process | GO:0002716 | 10 | 5 | 16441 | 2455 |
HLA-B,HLA-E,SERPINB9,HLA-A,TAP1 |
| 9.661e-03 | -4.64 | cell proliferation involved in kidney development | biological process | GO:0072111 | 10 | 5 | 16441 | 2455 |
BMP2,OSR1,BMP7,GPC3,STAT1 |
| 9.661e-03 | -4.64 | regulation of integrin activation | biological process | GO:0033623 | 10 | 5 | 16441 | 2455 |
FBLIM1,PIEZO1,KIF14,FARP2,PTGER4 |
| 9.661e-03 | -4.64 | early endosome to Golgi transport | biological process | GO:0034498 | 10 | 5 | 16441 | 2455 |
SNX8,RAB6A,STX10,LMAN1,TRAPPC10 |
| 9.661e-03 | -4.64 | bleb assembly | biological process | GO:0032060 | 10 | 5 | 16441 | 2455 |
P2RX7,EMP3,EMP2,MYLK,ANO6 |
| 9.661e-03 | -4.64 | positive regulation of receptor recycling | biological process | GO:0001921 | 10 | 5 | 16441 | 2455 |
SCRIB,ECE1,BVES,ARAP1,VAMP3 |
| 9.661e-03 | -4.64 | negative regulation of natural killer cell mediated cytotoxicity | biological process | GO:0045953 | 10 | 5 | 16441 | 2455 |
HLA-B,HLA-E,SERPINB9,HLA-A,TAP1 |
| 9.757e-03 | -4.63 | AGGGCAG,MIR-18A | MSigDB lists | AGGGCAG,MIR-18A | 134 | 30 | 17758 | 2588 |
EMX1,TIMP2,HMGN5,NF2,TACC1,CIT,TMEM55B,CALM1,ETV5,FURIN,ARL4C,UBE2Z,CALM3,BCL2L1,TRIB2,BAHD1,CYFIP2,DAG1,IL17RB,CALM2,SERTAD2,KHNYN,GATA2,LHX6,E2F1,GYS1,ZC3H12B,TLN2,CITED2,CBX7 |
| 9.757e-03 | -4.63 | CRX_NRL_DN.V1_UP | MSigDB lists | CRX_NRL_DN.V1_UP | 134 | 30 | 17758 | 2588 |
REC8,PCOLCE,PTPN18,SNTB2,ABCG4,PIP4K2C,PPARA,PDIA5,CAMK1D,GPSM2,MEST,GRTP1,DHRS3,STK17B,RHPN1,SEC14L2,IER3,SNTA1,AHRR,CDKN2C,LLGL2,ZDHHC12,KCNN4,SLC16A6,WWTR1,CNGA1,FAIM,TTC39C,ARL4D,ST3GAL1 |
| 9.770e-03 | -4.63 | CELL_PROLIFERATION_GO_0008283 | MSigDB lists | CELL_PROLIFERATION_GO_0008283 | 500 | 92 | 17758 | 2588 |
TXN,NF2,IL15RA,IL15,S100A11,CNOT8,TP53,ERBB2,COL18A1,CUL1,IL18,FTH1,KIF2C,CD274,TP53I11,FLT3,STIL,EMP2,TNFSF9,MXD1,CDKN2C,PDGFA,BTG3,PCNA,ARTN,IL31RA,ELF5,FABP6,DLG1,IRF2,TACSTD2,EPHB4,CDKN2D,CKS2,LAMP3,PLK1,ING1,PRKRA,CDC25C,SESN1,PGF,AREG,MAP3K11,KLF11,GAB1,CAPN1,BIN1,CDKN1C,IGFBP6,DHPS,EPS8,RACGAP1,TGFBR1,NOTCH2,JAG2,ETS1,CTNNBIP1,IGF1R,TIMP1,PTEN,CYR61,CKS1B,CD70,BUB1,PIM1,SYK,CCDC88A,QSOX1,TCFL5,EIF5A2,EMP3,CAPNS1,RUNX3,BCAR1,EGFR,CDK5R1,TSC1,BTG1,SCG2,ACVRL1,CSF1,CGREF1,NAB2,FGF18,APPL2,E2F1,OSMR,ICOSLG,CD81,CTBP1,TOB1,CD33 |
| 9.770e-03 | -4.63 | SYSTEM_DEVELOPMENT | MSigDB lists | SYSTEM_DEVELOPMENT | 842 | 147 | 17758 | 2588 |
DOC2A,GAA,UGT8,ACVR1,AGRN,RET,IL18,PLAC1,DNER,PICK1,CTGF,SHC3,DPYSL2,PAPSS1,IL31RA,ARNT2,SGCE,SOD1,ZBTB7B,COL12A1,DPYSL3,MDK,LIMK1,TBX1,BMP1,TMOD2,SERPINI1,APBA2,NRGN,PPP2R5D,NR2C2,FGD1,RUNX2,RACGAP1,NOTCH2,NCKAP1,APBA1,HPCAL4,ELF3,BMP2,OSTF1,NPTN,MYLIP,ETV7,ALDH3A2,SOCS5,DPYSL5,UFD1L,KLK5,PCDH1,GYLTL1B,MEST,NPHP3,DPYSL4,RHOB,RASA1,CDK5R1,ETS2,TIMM8A,COL13A1,HTT,ITGA7,CSF1,NAB2,ALPK3,EGFL7,KLK7,GDF11,DRP2,SHROOM2,RPS6KA3,MTM1,PAX6,NF2,PAPSS2,IRX4,COL18A1,ERBB2,MRAS,EGR3,EXT2,ARTN,LMO4,LHX6,TWIST1,EPHB4,FLOT2,DVL2,SEMA3B,MBP,UTRN,HTATIP2,RTN4RL1,ALDH5A1,PAFAH1B3,WFS1,SECTM1,TLE1,EFNA5,MAPK12,DYRK3,JRKL,CIT,CCM2,PBX3,AES,JAG2,CRABP2,ETS1,GSTP1,FGF19,NRP2,RND1,HDAC9,FOXP2,ADORA1,PTEN,CD9,BAX,TFAP2A,TRIM3,ERCC2,CITED2,RAG1,SGCB,SPRY2,SYK,FARP2,POU6F1,PDGFC,HES1,STMN3,COL7A1,BCL10,PITX2,BTG1,CTNS,DGCR2,ACVRL1,SCG2,ERAP1,PKD2,HOXB13,SOX8,SHOX2,L1CAM,JARID2 |
| 9.788e-03 | -4.63 | MAPK targets/ Nuclear events mediated by MAP kinases | REACTOME pathways | R-HSA-450282 | 30 | 10 | 8202 | 1235 |
MAPKAPK2,RPS6KA2,RPS6KA1,MAPK11,DUSP4,MAPK7,ELK1,FOS,PPP2R5D,RPS6KA3 |
| 9.791e-03 | -4.63 | HALLMARK_PROTEIN_SECRETION | MSigDB lists | HALLMARK_PROTEIN_SECRETION | 96 | 23 | 17758 | 2588 |
LAMP2,CLCN3,SOD1,CD63,COG2,VAMP3,ARFGEF1,VPS4B,EGFR,M6PR,GNAS,NAPG,ATP1A1,DNM1L,CTSC,OCRL,ARFGAP3,GLA,LMAN1,ABCA1,TMED2,RPS6KA3,TMX1 |
| 9.791e-03 | -4.63 | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN | MSigDB lists | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN | 96 | 23 | 17758 | 2588 |
HSP90B1,ADD1,ENO2,TUBB4B,SEC61G,LITAF,CAPNS1,ARHGDIB,MORF4L2,NPC2,CYFIP2,ERP29,GNAS,NUCB1,TAPBP,BTG1,RPL12,DDOST,METTL7A,UBE2J1,MDH1,LTA4H,CTBP1 |
| 9.806e-03 | -4.62 | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDM_UP | 196 | 41 | 17758 | 2588 |
HLA-E,SDC4,HMGN3,BCL2L1,GPSM2,SH3KBP1,APOBEC3B,PCNA,TFAP2A,PLEKHF1,IRF2,MDFIC,IQGAP3,ETHE1,SNX10,SMAGP,PHF20L1,NR3C1,MPP1,USP18,SAT1,NUB1,GRIN1,KIAA1109,FNDC3A,TANC1,RNPEP,SPTLC2,RHOB,HLA-B,ACADSB,PVRL2,CSF1,HDAC1,IRF7,STK39,ITGAV,CENPE,ITPKA,RGS14,JARID2 |
| 9.806e-03 | -4.62 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | 196 | 41 | 17758 | 2588 |
LAMP1,DNAJB2,TP53,GATA3,SELL,KCTD12,FAM101B,FAM46C,SIPA1L2,RALB,KCNN4,ZFP36,IL6ST,FOSB,FAM102A,ERCC2,PIM1,NR2C1,RPGR,CTDSP2,DUSP1,P2RX4,POU6F1,SUN2,PCCB,SNTB2,SLC11A2,TCF7,YES1,CYFIP2,SESN1,FOS,RHOB,SOCS3,TAPBP,FAAH,NR1D2,HOXA9,ARRB1,FAM134B,ABCG1 |
| 9.806e-03 | -4.62 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 196 | 41 | 17758 | 2588 |
KIF3C,KLF2,NQO1,AGRN,ATP9A,TRAF2,FAM134A,SPSB1,PHF1,AKIRIN1,SNX13,ST5,CA2,RALGPS2,CNTRL,SH3BP1,BCL6,TRIM21,ABCD1,NAGA,MX1,QSOX1,TIMP2,COL6A2,CTNNAL1,BSDC1,TCN2,SOX13,RASGRP2,NCOA3,RPL12,COQ10A,NR4A3,CANT1,ARFGAP3,RPL22,USF2,F2RL1,ST3GAL1,JARID2,ABCG1 |
| 9.806e-03 | -4.62 | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | MSigDB lists | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | 196 | 41 | 17758 | 2588 |
PLA2G4A,CD63,DGKQ,HABP4,DGKA,CALM3,ITPR2,PDGFB,GNB2,ITGA2B,CALM2,PDGFA,RAC2,GNB5,TIMP1,PLCG2,CD9,PIK3CA,F2R,DGKG,SYK,RASGRP1,TUBA4A,LAMP2,SOD1,RHOA,AKT1,PIK3R1,CALM1,PRKCQ,ITPR3,BCAR1,GNA11,DGKE,RHOB,RASGRP2,DGKH,FYN,SERPINA1,ARRB1,TRPC3 |
| 9.818e-03 | -4.62 | LIN_APC_TARGETS | MSigDB lists | LIN_APC_TARGETS | 75 | 19 | 17758 | 2588 |
CD99,SCN5A,AGRN,S100A4,CTDSPL,HMG20B,AES,SORBS3,ETS1,BCAP31,LMNA,CCND1,PCNA,MAP3K11,FLOT2,L1CAM,SYK,CAPN1,ABCC1 |
| 9.818e-03 | -4.62 | RADMACHER_AML_PROGNOSIS | MSigDB lists | RADMACHER_AML_PROGNOSIS | 75 | 19 | 17758 | 2588 |
FARP1,AGRN,CTNNAL1,FHL2,EZR,PBX3,FLT3,SNX9,HOXB2,NFIB,TSPAN7,ENDOD1,PLCG1,SRPX,IL6ST,VASN,DAPK1,TACSTD2,DMWD |
| 9.818e-03 | -4.62 | MAHAJAN_RESPONSE_TO_IL1A_DN | MSigDB lists | MAHAJAN_RESPONSE_TO_IL1A_DN | 75 | 19 | 17758 | 2588 |
NEK4,CTNNAL1,ASAH1,KDELR3,COL4A5,CRABP2,FOS,LMNA,PLS3,TGFBR3,PCNA,CTGF,PTEN,MITF,RYK,PRKCI,ALDH7A1,EPHB4,ALDH3A2 |
| 9.830e-03 | -4.62 | positive regulation of stress-activated MAPK cascade | biological process | GO:0032874 | 131 | 30 | 16441 | 2455 |
MAP3K3,TAOK2,RIPK2,FZD4,TRAF2,EPHA4,PKN1,FGF19,MAP3K6,FZD7,BMP2,PDCD10,CTGF,ANKRD6,KIAA1804,MAP3K9,MAP3K11,NOD2,DAB2IP,MDFIC,FZD5,MAP3K5,MAP3K7,F2RL1,SYK,GAB1,RASGRP1,DVL2,MDFI,XDH |
| 9.830e-03 | -4.62 | negative regulation of cell projection organization | biological process | GO:0031345 | 131 | 30 | 16441 | 2455 |
SEMA6B,RHOA,CIT,RAPGEF2,EPHA4,LRP4,ULK2,CDK5R1,DPYSL3,ARHGAP24,SPP1,ITGA3,SEMA4D,PTEN,PLK2,KIAA0319,RAB29,TACSTD2,SEMA3G,EFNA1,ARF6,NTN1,WNT3A,GFI1,RAP1GAP,ITM2C,SEMA3A,SPRY2,NGEF,SEMA3B |
| 9.834e-03 | -4.62 | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | 642 | 115 | 17758 | 2588 |
SUN1,SIGIRR,SPRED1,AVPI1,FAM92A1,RET,MCCC1,SOD2,TP53I11,SYTL4,ERP29,FLT3,KREMEN1,DENND2D,NCS1,ZNF275,PER2,TTC21B,RGS3,OSBPL3,SMO,EPB41L4B,EGLN3,DLG3,SMYD5,FGFR1OP2,CAMSAP3,TNFAIP8L1,NKAIN1,SLC17A5,RAB38,TMTC2,SESN1,DAG1,C3orf33,ARHGAP35,MAN2A2,ALDH5A1,MPRIP,KLF12,C19orf66,DNM1L,NGFRAP1,HOXA9,ZNF704,PNPLA6,PRDM5,DHTKD1,NFKBIZ,TTC9,NRGN,STARD13,MAMDC2,RUNX2,GCAT,UBASH3B,ITGA6,TRAF2,ISYNA1,HES2,LGALS3BP,FZD6,DNAJB9,PARM1,SLC25A36,SYDE2,IRF2BPL,BMP2,CALR,IRAK1,ITGB8,GATA2,PAIP2B,LYPD6,OCRL,FUT8,DAPK1,MSH2,MTMR10,PLEKHF1,MAPK11,KANK2,FAM84B,C8orf58,ACAD8,TTPA,TLE6,HP1BP3,KDELR1,C9orf9,ABCC1,QSOX1,FADS2,PDGFC,TGIF1,PGM1,WDR72,HMGN5,CORO2A,NUB1,LRRC1,BCAR1,PRKAG2,INSR,ITPR1,FGF18,WDR19,C1orf21,PGRMC1,CLIP4,EFNA1,ZMIZ1,DCBLD1,SNX30,PHC1 |
| 9.846e-03 | -4.62 | cellular response to organic cyclic compound | biological process | GO:0071407 | 364 | 71 | 16441 | 2455 |
CASP3,TRIM24,SSH1,IL15,THRA,P2RX7,IL18,ITPR2,CCNB1,PRKACA,PDGFB,CYP1A1,CDH1,CTNNB1,RALB,SMO,DNM2,CDKN1B,PDE4D,IFIT1,OSBPL7,TIPARP,NR2C1,SP5,CYP1B1,THRB,SOD1,AKT1,DMTN,CASP9,EZR,AGO4,PRKRA,PTGS2,ATP1A1,NR3C2,NR2C2,KLF2,HSP90B1,NKX3-1,SERPINB9,FLOT1,GABRG2,TFAP4,BMP2,BMP7,PAK2,KLF9,PIM1,PAQR7,HCN3,P2RX4,SHMT1,WNT10B,NR3C1,NR4A1,RAPGEF2,PPARA,ELK1,EGFR,GPLD1,FECH,GNAS,NCOA3,NR1D2,NR4A3,NR4A2,GPER1,RARG,TMEM173,DRD1 |
| 9.857e-03 | -4.62 | RasGEF | pfam domains | PF00617 | 30 | 10 | 16629 | 2504 |
BCAR3,RASGRF1,RALGPS2,RAPGEF2,KNDC1,SH2D3C,RASGRP3,RASGEF1A,RASGRP1,RASGRP2 |
| 9.867e-03 | -4.62 | cysteine-type peptidase activity | molecular function | GO:0008234 | 170 | 37 | 16491 | 2452 |
OTUD5,CASP3,CAPN12,CTSB,PDIA3,CTSZ,ATG4A,CAPN2,OTUD1,CTSC,ALG13,USP38,USP1,TINAGL1,LGMN,ZRANB1,ATG4D,GCA,UFD1L,USP31,TNIP1,CAPN6,USP18,CASP9,CAPNS1,CASP4,USP6,CTSL,CASP7,OTUD6B,CTSV,OTUB2,YOD1,ESPL1,CAPN1,USP43,USP16 |
| 9.867e-03 | -4.62 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | 162 | 35 | 17758 | 2588 |
CASP3,DYNLRB1,FARP1,S100A11,HABP4,OSGIN2,GATA3,KCTD12,RASGRP3,CD274,UHRF1BP1L,CTSC,RALB,FRAS1,DACT1,GTF2F2,PTPRE,SNX10,RASGRP1,ZNF462,PHF20L1,DDB2,RIPK2,MAPKAPK3,FMN1,SLC39A8,BCL9,SLC11A2,STK17B,FRMD4B,NCOA3,PAFAH1B3,SPINT2,RAB11FIP1,FAM45A |
| 9.868e-03 | -4.62 | TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | REACTOME pathways | R-HSA-975138 | 83 | 21 | 8202 | 1235 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 9.873e-03 | -4.62 | SLMAP (sarcolemma associated protein) | protein interactions | 7871 | 46 | 14 | 16036 | 2547 |
MOB4,PDCD10,STK26,LYPD3,STRIP2,CENPJ,FRYL,STRN4,CNTROB,HDAC6,ZRANB1,F2RL1,FGFR1OP2,STX3 |
| 9.873e-03 | -4.62 | TFAP2A (transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)) | protein interactions | 7020 | 46 | 14 | 16036 | 2547 |
CASP3,RB1,LDLRAP1,KCTD15,CTNNB1,CITED4,EPAS1,MKRN3,SH3BP4,TP53,AURKA,WWP1,CITED2,WWP2 |
| 9.886e-03 | -4.62 | central_nervous_system-brain-glioma-ependymoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_II | 14 | 6 | 17775 | 2585 |
TSC1,RB1,NF2,AKT1,IDH1,PTEN |
| 9.886e-03 | -4.62 | soft_tissue-small_round_cell_tumour | COSMIC cancer mutations | soft_tissue-small_round_cell_tumour | 14 | 6 | 17775 | 2585 |
GATA3,ERBB2,SS18,EGFR,PIK3CA,TP53 |
| 9.886e-03 | -4.62 | small_round_cell_tumour | COSMIC cancer mutations | small_round_cell_tumour | 14 | 6 | 17775 | 2585 |
GATA3,ERBB2,SS18,EGFR,PIK3CA,TP53 |
| 9.886e-03 | -4.62 | chondroid | COSMIC cancer mutations | chondroid | 14 | 6 | 17775 | 2585 |
CTNNB1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 9.886e-03 | -4.62 | bone-vertebrae-chordoma-chondroid | COSMIC cancer mutations | bone-vertebrae-chordoma-chondroid | 14 | 6 | 17775 | 2585 |
CTNNB1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 9.886e-03 | -4.62 | adrenal_cortical_hyperplasia | COSMIC cancer mutations | adrenal_cortical_hyperplasia | 14 | 6 | 17775 | 2585 |
GNAS,ATP1A1,CACNA1D,CTNNB1,AMER1,PRKAR1A |
| 9.947e-03 | -4.61 | positive regulation of organelle assembly | biological process | GO:1902117 | 44 | 13 | 16441 | 2455 |
CNOT2,RHOA,HTT,RALB,SDC4,VPS4B,CAPG,PLK4,PIP4K2C,CNOT6L,SDC1,MNS1,LCP1 |
| 9.951e-03 | -4.61 | POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 45 | 13 | 17758 | 2588 |
SOD1,MADD,KIAA1804,MAP3K11,MAP3K9,ERBB2,MDFIC,MAP3K5,PKN1,CD81,MAP3K6,EGFR,MDFI |
| 9.951e-03 | -4.61 | PID_RHOA_PATHWAY | MSigDB lists | PID_RHOA_PATHWAY | 45 | 13 | 17758 | 2588 |
RHOA,PPP1R12A,PTEN,CYR61,LIMK1,CIT,EZR,CDKN1B,PLD2,PLD1,PKN1,FOS,MAPK12 |
| 9.951e-03 | -4.61 | GCM_AQP4 | MSigDB lists | GCM_AQP4 | 45 | 13 | 17758 | 2588 |
GPRC5B,SLC4A4,CASC4,TACC1,SCD5,LRP4,LRIG1,NDRG2,C1orf198,TMOD2,ARNT2,DNER,BBS2 |
| 9.951e-03 | -4.61 | ST_T_CELL_SIGNAL_TRANSDUCTION | MSigDB lists | ST_T_CELL_SIGNAL_TRANSDUCTION | 45 | 13 | 17758 | 2588 |
PAK6,PLCG1,NFKBIE,NFKBIA,PAK2,RASGRP3,ITPKA,CBL,NFKB2,NFAT5,DAG1,RASGRP1,RASGRP2 |
| 9.951e-03 | -4.61 | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS | MSigDB lists | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS | 45 | 13 | 17758 | 2588 |
TXN,IRAK1,RIPK2,TAB3,CASP9,NOD2,P2RX7,MAPK11,MAPK13,BCL2L1,MAP3K7,CASP4,MAPK12 |
| 9.951e-03 | -4.61 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | 45 | 13 | 17758 | 2588 |
LMO7,AKIRIN1,TGFBR3,GATA2,P4HA2,DNAJC3,ETNK1,SGK1,PDK3,PNKD,BMP2K,RHOB,CYP26A1 |
| 9.957e-03 | -4.61 | dysplasia | COSMIC cancer mutations | dysplasia | 18 | 7 | 17775 | 2585 |
GNAS,ERBB2,CTNNB1,IDH1,PTEN,EGFR,TP53 |
| 9.957e-03 | -4.61 | NS-mesothelioma | COSMIC cancer mutations | NS-mesothelioma | 18 | 7 | 17775 | 2585 |
ERBB2,CTNNB1,AKT1,FLT3,EGFR,RET,PIK3CA |
| 9.957e-03 | -4.61 | salivary_gland-carcinoma-ex-pleomorphic_adenoma_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-ex-pleomorphic_adenoma_carcinoma | 18 | 7 | 17775 | 2585 |
ERBB2,CTNNB1,CHCHD7,PTEN,EGFR,PIK3CA,TP53 |
| 9.957e-03 | -4.61 | ex-pleomorphic_adenoma_carcinoma | COSMIC cancer mutations | ex-pleomorphic_adenoma_carcinoma | 18 | 7 | 17775 | 2585 |
ERBB2,CTNNB1,CHCHD7,PTEN,EGFR,PIK3CA,TP53 |
| 9.957e-03 | -4.61 | endometrium-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-clear_cell_carcinoma | 18 | 7 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,PTEN,PIK3R1,PIK3CA,TP53 |
| 9.972e-03 | -4.61 | V$FOXO4_01 | MSigDB lists | V$FOXO4_01 | 225 | 46 | 17758 | 2588 |
LZTFL1,FRMD4A,CHCHD7,THRA,NDRG1,ETV5,BIK,FAM134A,CACNA2D2,DHRS3,ZNF385B,ZFYVE9,MECOM,NEO1,HDAC9,FOXP2,SESN3,ST5,CYR61,IL6ST,LMO4,VASN,TSPAN13,PDE4D,CITED2,PLCB2,ETV4,MAP3K3,TGIF1,TAF5,KIF20A,NR3C1,ASXL1,RGAG1,LRRC1,LDB2,H2AFV,KDM3A,NFIB,CRTC2,KLF12,SLC4A4,NRG1,C1orf43,SHOX2,MAFF |
| 9.974e-03 | -4.61 | ADD2 (adducin 2 (beta)) | protein interactions | 119 | 13 | 6 | 16036 | 2547 |
FYN,ADD1,PRKACA,ANKRD29,DEF6,CALM1 |
| 9.974e-03 | -4.61 | TAPBP (TAP binding protein (tapasin)) | protein interactions | 6892 | 13 | 6 | 16036 | 2547 |
PDIA3,CALR,HLA-C,HLA-A,COPG1,TAP1 |
| 9.974e-03 | -4.61 | SNTB1 (syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)) | protein interactions | 6641 | 13 | 6 | 16036 | 2547 |
KCNJ12,SCN5A,SAV1,ABCA1,MAPK12,UTRN |
| 9.974e-03 | -4.61 | PGM3 (phosphoglucomutase 3) | protein interactions | 5238 | 13 | 6 | 16036 | 2547 |
PGM1,GLO1,LACTB2,UAP1,SPRTN,DCP2 |
| 9.974e-03 | -4.61 | Mzt2 (mitotic spindle organizing protein 2) | protein interactions | 72083 | 13 | 6 | 16036 | 2547 |
TUBG1,MZT2A,MZT1,PRICKLE3,LGALS3BP,TUBGCP6 |
| 9.974e-03 | -4.61 | INCENP (inner centromere protein) | protein interactions | 3619 | 13 | 6 | 16036 | 2547 |
AURKA,AURKB,SGOL1,CBX5,CDCA8,FLOT1 |
| 9.974e-03 | -4.61 | HBEGF (heparin-binding EGF-like growth factor) | protein interactions | 1839 | 13 | 6 | 16036 | 2547 |
FBLN1,CD82,LTBP3,EGFR,CD9,BCL6 |
| 9.974e-03 | -4.61 | Cd2ap (CD2-associated protein) | protein interactions | 12488 | 13 | 6 | 16036 | 2547 |
KIF23,RACGAP1,RTKN2,SH3D19,SH3KBP1,ARAP1 |
| 9.974e-03 | -4.61 | VMA21 (VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)) | protein interactions | 203547 | 13 | 6 | 16036 | 2547 |
ECE1,NPTN,PLIN3,OXCT1,PLAUR,TMEM9 |
| 9.989e-03 | -4.61 | KINESIN_COMPLEX | MSigDB lists | KINESIN_COMPLEX | 14 | 6 | 17758 | 2588 |
KIF23,KIF5B,KIF3C,KIF2C,KIF11,KLC2 |
| 9.989e-03 | -4.61 | MATZUK_OVULATION | MSigDB lists | MATZUK_OVULATION | 14 | 6 | 17758 | 2588 |
SIRT1,PTGS2,PDE4D,LFNG,IL6ST,NR2C2 |
| 9.989e-03 | -4.61 | ROETH_TERT_TARGETS_UP | MSigDB lists | ROETH_TERT_TARGETS_UP | 14 | 6 | 17758 | 2588 |
PLA2G4A,HERC5,MX1,IFIT1,IFIT3,HERC6 |
| 9.989e-03 | -4.61 | PROTEIN_TETRAMERIZATION | MSigDB lists | PROTEIN_TETRAMERIZATION | 14 | 6 | 17758 | 2588 |
ALDH5A1,INSR,IGF1R,AASS,TP53,CDA |
| 9.989e-03 | -4.61 | CASTELLANO_NRAS_TARGETS_DN | MSigDB lists | CASTELLANO_NRAS_TARGETS_DN | 14 | 6 | 17758 | 2588 |
CYHR1,RPS6KA2,NCAM1,LIMK1,PLEKHO1,PKIA |
| 9.989e-03 | -4.61 | VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_UP | MSigDB lists | VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_UP | 14 | 6 | 17758 | 2588 |
PITX2,TRPC1,CDK18,ST13,DHPS,PRKAR1A |
| 9.991e-03 | -4.61 | Role of second messengers in netrin-1 signaling | REACTOME pathways | R-HSA-418890 | 10 | 5 | 8202 | 1235 |
TRPC1,PITPNA,PLCG1,NTN1,TRPC3 |
| 9.991e-03 | -4.61 | Ligand-independent caspase activation via DCC | REACTOME pathways | R-HSA-418889 | 10 | 5 | 8202 | 1235 |
DAPK2,CASP3,UNC5B,CASP9,DAPK1 |
| 9.997e-03 | -4.61 | V$AP1FJ_Q2 | MSigDB lists | V$AP1FJ_Q2 | 260 | 52 | 17758 | 2588 |
CMAS,SORT1,FARP1,IGFBP6,SCOC,TRIP10,CAMKK1,BLVRB,ETV5,CALM3,PLAC1,SLC20A1,PRKACA,S100A2,SLC35E4,LTBP3,SIX4,ZNF385B,LMNA,CALM2,PAK6,IRAK1,ITGB8,SHC3,KCNN4,NECAB3,SLC16A6,TAGLN2,MDFI,WBP5,SMARCA2,TRIM8,CASK,DSTN,PTPRH,CALM1,DCHS1,KBTBD8,CAPNS1,KDM3A,FOS,MPRIP,TBC1D17,MAP2,CORO1C,S100A5,GRIN2D,HS3ST3B1,EFNA1,UBE2C,RTN3,TOB1 |
| 1.001e-02 | -4.60 | Loss of Nlp from mitotic centrosomes | REACTOME pathways | R-HSA-380259 | 63 | 17 | 8202 | 1235 |
PLK1,CEP70,TUBB4B,PRKAR2B,PRKACA,CDK1,CKAP5,CNTRL,CENPJ,CEP78,PLK4,NEK2,TUBG1,SSNA1,NDE1,CEP41,TUBA4A |
| 1.001e-02 | -4.60 | Loss of proteins required for interphase microtubule organizationfrom the centrosome | REACTOME pathways | R-HSA-380284 | 63 | 17 | 8202 | 1235 |
PLK1,CEP70,TUBB4B,PRKAR2B,PRKACA,CDK1,CKAP5,CNTRL,CENPJ,CEP78,PLK4,NEK2,TUBG1,SSNA1,NDE1,CEP41,TUBA4A |
| 1.001e-02 | -4.60 | Asymmetric localization of PCP proteins | REACTOME pathways | R-HSA-4608870 | 63 | 17 | 8202 | 1235 |
PSMB4,FZD4,PSME2,PSMD7,PRICKLE1,PSMD10,SCRIB,PSME1,PSMA4,FZD7,PSMD1,PSMD3,PSMC2,FZD5,PSMC1,PSMA5,DVL2 |
| 1.002e-02 | -4.60 | DAGK_acc | pfam domains | PF00609 | 10 | 5 | 16629 | 2504 |
DGKH,DGKG,DGKQ,DGKE,DGKA |
| 1.002e-02 | -4.60 | Amidohydro_1 | pfam domains | PF01979 | 10 | 5 | 16629 | 2504 |
DPYSL5,DPYSL4,AMDHD1,DPYSL2,DPYSL3 |
| 1.002e-02 | -4.60 | WWE | pfam domains | PF02825 | 10 | 5 | 16629 | 2504 |
PARP12,PARP14,RNF146,DDHD2,DTX4 |
| 1.003e-02 | -4.60 | myeloid cell homeostasis | biological process | GO:0002262 | 94 | 23 | 16441 | 2455 |
KLF2,CASP3,SOD1,DYRK3,ADD1,EPAS1,THRA,DMTN,NFE2L1,GATA3,SLC11A2,MECOM,FECH,SFXN1,RB1,TGFBR3,AXL,BCL6,BAX,PTBP3,ERCC2,JAK3,SLC25A38 |
| 1.003e-02 | -4.60 | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | MSigDB lists | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | 337 | 65 | 17758 | 2588 |
MYL9,KIAA1462,XYLT1,LMCD1,KCTD12,IL18,PLS3,CTGF,DACT1,PLCG2,AKR1B1,TRPC1,TWIST1,ACSL4,LOXL1,F2R,SEC23A,CD55,COL6A2,S100A4,ROR1,LOXL2,LDB2,TP53I3,ATP10D,EDNRA,DPYSL3,FYN,ANKRD6,AXL,SLC9A6,WWTR1,PRKCDBP,RCAN2,MRC2,PLSCR4,SERPINE2,NUAK1,ETV5,ARL4C,DSE,MERTK,ARHGEF40,SRPX2,TNS3,CYR61,CALD1,COL6A1,SGK1,FXYD5,SGCB,ELK3,TACC1,PLAUR,EMP3,CRISPLD2,FAS,MAP1B,IL1R1,TIMP3,RCBTB2,PKD2,GEM,SHOX2,COL16A1 |
| 1.003e-02 | -4.60 | ampulla_of_Vater | COSMIC cancer mutations | ampulla_of_Vater | 50 | 14 | 17775 | 2585 |
GNAS,MAN2B2,CTNNB1,CDH1,AKT1,IQCE,MSH2,PIK3CA,TP53,ANXA9,BLVRA,EGFR,SCN3A,MSH6 |
| 1.003e-02 | -4.60 | SANSOM_APC_MYC_TARGETS | MSigDB lists | SANSOM_APC_MYC_TARGETS | 202 | 42 | 17758 | 2588 |
FOXM1,LFNG,FLYWCH2,SH3D19,THRA,ADO,TP53,ARFGEF1,BCL2L1,RAD23A,CCND1,BMP7,SIVA1,FUT8,FAM63A,TNFRSF12A,NFKB2,MAPK7,SGCB,MED22,MCCC2,SEMA3B,OPLAH,SHMT1,CENPA,PSRC1,NUB1,GYLTL1B,WHSC1,VEZT,TRIM7,DAG1,SCRN2,SLC6A6,DNM1L,SEMA4D,ZMYND19,CORO1C,AMMECR1,WDR62,FZD5,ATMIN |
| 1.003e-02 | -4.60 | TTTGCAG,MIR-518A-2 | MSigDB lists | TTTGCAG,MIR-518A-2 | 202 | 42 | 17758 | 2588 |
ZMAT1,SORBS1,PPP1R12A,CPEB4,NDRG1,XIAP,OSGIN2,MIER3,EGR3,RAB6A,PJA2,SIPA1L2,CTNNB1,DAPK1,BRI3,EPB41L4B,PACSIN1,MAP3K3,LAMP2,PCGF5,TIMP2,MLEC,MMD,TACC1,SEPT6,ITCH,RNF11,FAM133B,PTGFRN,ZFAND5,USP6,PTPRF,STK38,CORO1C,RAP2C,FAM117A,YOD1,GDF11,HMGA1,CPEB2,NR3C2,FOXA1 |
| 1.003e-02 | -4.60 | Golgi vesicle transport | biological process | GO:0048193 | 277 | 56 | 16441 | 2455 |
LAMP1,SORT1,TRAPPC10,ATP9A,SH3D19,TRAPPC8,CTSZ,TGOLN2,FTH1,RAB6A,BCAP31,PICK1,NAPG,DOPEY2,ANK1,AP1M2,CTSC,ARL1,LMAN2L,STEAP2,PRKCI,DNM2,SORL1,RP2,LMAN1,TFG,PPP6R1,TMED2,MYO5A,SNX8,SEC23A,GCC2,COG2,VAMP3,KIF1C,KIF13A,COL7A1,ARFRP1,RAB3IP,MCFD2,BBS2,VCP,OPTN,RGPD5,TAPBP,AP1AR,STX10,SERPINA1,AREG,HTT,WIPI1,RAB31,ARRB1,RAB29,NRBP1,COPG1 |
| 1.004e-02 | -4.60 | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | 3665 | 578 | 17775 | 2585 |
IBTK,GRIK2,PNPLA2,HEXB,RET,DHX8,FAM102B,LGI3,CA8,BARD1,KIF26A,GRM5,ZYX,RGS12,DNAH6,PPP1R16A,SLC46A1,DNM2,CLDN4,RNF26,TIAM1,ERAP2,TUBA4A,TNIP1,MTRF1L,KDELR3,RNF19B,COL12A1,GRID2IP,ATP7B,CELF5,NOD2,ARF6,ITGA6,SOX9,MARCH8,SH3D21,FRY,MEGF8,ZIC5,FAM13B,PCYOX1,SLAIN2,CADPS2,USP38,ALPK1,CNGA1,MAPK7,MYLIP,DGKG,KIF20A,SHARPIN,FHL2,NPHP3,GOLT1A,RHOB,STK17A,PTPRF,NCOA3,SLC4A4,HTT,SETD3,ITPR1,CLMN,OSMR,DYSF,ALG2,DRP2,ZNF502,TMEM173,RUSC1,XDH,DOCK9,LFNG,FAM131C,RGS20,PKP2,GRK6,APC2,TNFSF9,ZNF385B,UHRF1BP1L,MUC16,DACT1,ENPP5,ZNF365,SCN3A,TMCC2,ERMP1,RIPK2,SEPT6,SYNE2,VPS4B,CDCA2,NUSAP1,SYP,TANC1,STX10,SHROOM3,SLC9A6,WWTR1,PLEKHG1,PNPLA6,PDXK,TTC8,FARP1,HSP90B1,TNRC6C,NKX3-1,TAOK2,PARP14,CKAP2,MAN1A2,OSGIN2,PDIA3,PKN1,ETS1,NFAT5,ADD3,FUT2,SLC27A6,FAM160A2,KNDC1,TUBGCP6,ADAM15,TMBIM6,WWP1,SGCB,CASD1,TPCN1,MED22,HCN3,PVRL4,LCA5,FAM160A1,RAPGEF2,PIK3R1,NUB1,GRIN1,AK4,FAM109A,CRISPLD2,TXK,GALNT3,SYT7,ACVRL1,CENPE,SHOX2,ACOT7,FOXA1,TLL2,TRIM2,AGRN,EPAS1,ARFGEF1,NDC80,MCCC1,DNAJB11,PHOSPHO1,TEX2,SPTB,FANCI,PLS3,SUSD2,CPNE2,ENTPD4,CTNNB1,RABEP2,IL6ST,ABCA2,DUSP10,TNFRSF18,TLN2,NEB,SMAGP,ZNF462,THRB,MARK1,CELSR2,ZBTB7B,DZIP1L,TNS4,PLEKHG6,MFAP3L,HS6ST1,MSL1,CDCA4,MAP2,RAB11FIP1,PIEZO1,GLCCI1,PRKAA2,PARP12,USH1C,UBASH3B,PSMD7,ADCK5,CNTNAP2,NCKAP1,RSAD1,PGAP1,SSX2IP,MYO5C,CORO1B,TNS3,RB1,FRAS1,KIF13B,EXOC8,PIM1,PLCB2,ABCC1,DPYSL5,PLEKHA6,USP31,BTNL9,STRADB,BCL2L13,G2E3,PRX,COQ10A,CSF1,MFSD2A,PHLPP2,OTUD6B,SLC2A6,SEMA3A,XYLT1,DGKA,TP53,RHPN2,SLC7A2,CCNL1,PCBP1,SDF4,SYTL2,PER2,TTC21B,TACC2,WDR44,PLCG2,SRR,NOTCH3,OAS3,GM2A,CPD,SIRT1,TMTC1,PTGER4,IDE,RBL1,ADAMTS14,CDH22,TAB3,RUSC2,GNAL,GABRG2,NKRF,JAG2,DSE,VPS26A,SLC9A2,SIRPA,CEP97,MAGEE1,IL17RA,TSPAN13,ATP2B1,GCNT1,DLGAP1,AMFR,PPARA,DPP9,PRICKLE1,COL7A1,PELI3,TXNDC11,BSDC1,FUCA1,FAT4,SCG2,NMI,TMC5,NETO2,CLIP4,PPP2R3C,SH3BGRL2,ICOSLG,TBC1D4,HIPK3,ARHGEF9,ARHGEF4,GOLGB1,DIS3L,FAM171B,GAA,HSPG2,C1orf198,GATA3,PSME1,CCNB1,PJA2,SEPT4,FAM101B,SLC9A7,PICK1,OSBPL3,PIK3CA,STEAP2,POLL,IQCD,METAP2,SPATA18,MGAM,TNS1,KIF13A,PIF1,AHRR,SLC25A4,PLK2,TBX1,LRIG1,SERPINI1,EIF4EBP2,TANC2,F2RL1,CCDC97,RECQL,CDK17,FRMD4A,TBC1D1,KIF23,C6orf106,NOTCH2,PDXDC1,PSIP1,MECOM,C9orf69,DOPEY2,ITGA3,PIK3AP1,NECAB3,BHLHE41,BDH1,PRKG1,DAPK1,SORL1,CACNA1D,RIMS2,DNAI1,SPATA20,PMPCB,KIAA1841,CEP89,ANO6,DCHS1,KDM3A,FBXO10,RASA1,PDE11A,MMP15,TJP3,ISM1,SLC4A3,AGBL5,ARAP1,PIAS2,PCDH19,MAP3K5,IFIH1,PKD1L2,FRMPD3,PLA2G4A,SLC2A4,REPS2,TCTN2,NLRX1,TRIP10,CERCAM,RALBP1,IQGAP1,ATP2C2,KCTD12,RNF182,FLT3,GNB2,ACAP2,DAB2IP,RNASEH2A,IFIT1,LGMN,NAGA,GPX4,TBC1D10B,MYO5B,DOCK4,SLC5A11,CDKN2AIP,PANK1,TEP1,UTRN,CLSTN1,KIF1C,PKMYT1,C15orf39,ITPR3,B3GALNT2,ALCAM,ATP10D,CMTM7,AMZ2,FYN,ACAD10,KIAA1804,ZNF704,SLC27A1,NRG1,HS3ST3B1,ZC3H12B,SLC27A3,DENND5B,PCOLCE,HAPLN3,NES,CBLL1,DNAH3,PNPLA5,SIX4,SCML1,WWP2,AKIRIN1,OXCT1,MGAT1,PTEN,FUT8,ATP8B1,ERBB3,GFI1,SPRY2,SMC4,TGIF1,RASGRF1,CASK,ARHGEF28,ZWINT,ERMAP,PAPD7,TEF,ZKSCAN2,MAMDC4,SLC25A40,RIN3,TBX18,ABCB1,NCAPG2,USP16,RGMA,ESYT2,UGT8,VARS2,CACNB4,DNER,KREMEN1,TMC1,PTCHD4,ARHGEF10L,LRRC6,ZCCHC12,ANKFN1,ANKRD12,ARNT2,PTPRE,BTBD3,LAMP3,TDP1,ASXL1,SYNE3,RGAG1,ARHGDIB,PTGFRN,TCN2,LRRC42,ARHGEF19,NEIL1,APBA2,PPP2R5D,PCSK5,ARAP3,ETV5,ABCG2,ATP6V1E2,CALM3,PHLPP1,ADAMTSL4,LYSMD4,ZNF432,CA2,FAM20C,COL6A1,RFX5,SLC12A2,SNED1,MDFI,SNX7,PARD3B,GYLTL1B,PDE5A,KIAA1109,NUBP1,EGFR,MUM1L1,SOX13,GNAS,XKRX,SLC6A6,CGREF1,ALPK3,JAK3,RARG,COL16A1,FBXW5,PROM2,NCKAP5,TDRKH,PHLDA1,EXT2,ARHGEF16,SS18,REEP1,SMO,APIP,ECE1,EPB41L4B,PDIA6,DOCK5,ARHGAP35,BHLHB9,PTBP3,OVOL1,SPTBN5,RCAN2,CYP2U1,LIFR,ABCA1,ARHGEF11,FRMD6,SERPINB9,MIER3,TGFBR1,COL4A5,SBF1,HMGXB4,SYDE2,HDAC9,SAC3D1,IRF2BPL,TOP2A,MDM1,LLGL2,RRBP1,CLIP2,SUN2,PGM1,DCAF6,ADAM17,ASPM,RC3H2,LRRC66,LEPR,MAP1B,ARHGAP24,FIBCD1,ARRB1,GRAMD1C,HOXB13,SOX8,RAB3IL1,LRRC57 |
| 1.005e-02 | -4.60 | SESTO_RESPONSE_TO_UV_C1 | MSigDB lists | SESTO_RESPONSE_TO_UV_C1 | 70 | 18 | 17758 | 2588 |
TNIP1,SOD2,ATP1B1,DUSP5,SPAG1,GALNT3,CTGF,KCNK1,CYR61,PSMC2,UBE2D2,HDAC1,PIM1,IFIT1,SULT2B1,SLC31A2,PSMC1,PSMA5 |
| 1.005e-02 | -4.60 | BOYLAN_MULTIPLE_MYELOMA_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_DN | 70 | 18 | 17758 | 2588 |
ARAP2,CASK,SLC37A1,NFKBIE,CTDSPL,PRKRA,CASP7,SH3BP1,AIM1,NAB2,DRAM1,TDRD7,CMPK2,FLOT2,LIFR,S100A13,CCDC88A,S100A6 |
| 1.005e-02 | -4.60 | Oncostatin M Signaling Pathway | WikiPathways | WP2374 | 63 | 18 | 4455 | 729 |
CASP3,AKT1,PIK3R1,TP53,FOS,SOCS3,PIAS3,CASP7,TIMP3,JAK1,CYR61,IL6ST,NFKBIA,STAT1,CDKN1B,OSMR,JAK3,LIFR |
| 1.006e-02 | -4.60 | ANATOMICAL_STRUCTURE_MORPHOGENESIS | MSigDB lists | ANATOMICAL_STRUCTURE_MORPHOGENESIS | 367 | 70 | 17758 | 2588 |
GAA,PAX6,SSH1,GATA3,COL18A1,IL18,PLAC1,IER3,LMO4,DLG1,TWIST1,EPHB4,NOTCH3,RCAN3,F2R,SEMA3B,SOD1,NFE2L1,HTATIP2,RTN4RL1,KCNMB4,SHROOM3,TBX1,TLE1,ARF6,HOXC13,FGD1,GCLM,ARAP3,TAOK2,CCM2,AES,NOTCH2,NRP2,SCML1,ELF3,ANK1,CYR61,GPC3,BAX,CD9,PRKCI,ERCC2,ETV7,SYK,SPRY2,CCDC88A,DPYSL5,GCLC,WHSC1,CDK5R1,RASA1,RHOB,SOX13,BCL10,PITX2,BTG1,DGCR2,HTT,COL13A1,SCG2,ACVRL1,FGF18,ARAP1,ERAP1,FGD6,EGFL7,PKD2,FZD5,SHROOM2 |
| 1.007e-02 | -4.60 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | REACTOME pathways | R-HSA-176814 | 73 | 19 | 8202 | 1235 |
PLK1,PSMB4,PSME2,PTTG1,CDC20,PSMD7,PSMD10,PSME1,CCNB1,CDK1,PSMA4,CCNA2,PSMD1,PSMD3,PSMC2,NEK2,UBE2C,PSMC1,PSMA5 |
| 1.007e-02 | -4.60 | Recruitment of mitotic centrosome proteins and complexes | REACTOME pathways | R-HSA-380270 | 73 | 19 | 8202 | 1235 |
PLK1,CEP70,TUBB4B,PRKAR2B,CCNB1,PRKACA,CDK1,CKAP5,CNTRL,CENPJ,TUBGCP6,CEP78,PLK4,NEK2,TUBG1,SSNA1,NDE1,CEP41,TUBA4A |
| 1.007e-02 | -4.60 | Centrosome maturation | REACTOME pathways | R-HSA-380287 | 73 | 19 | 8202 | 1235 |
PLK1,CEP70,TUBB4B,PRKAR2B,CCNB1,PRKACA,CDK1,CKAP5,CNTRL,CENPJ,TUBGCP6,CEP78,PLK4,NEK2,TUBG1,SSNA1,NDE1,CEP41,TUBA4A |
| 1.007e-02 | -4.60 | BOYAULT_LIVER_CANCER_SUBCLASS_G6_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G6_DN | 18 | 7 | 17758 | 2588 |
TNS1,HES1,CDH1,SLC20A1,CMTM6,RRBP1,SDC4 |
| 1.007e-02 | -4.60 | CHEN_PDGF_TARGETS | MSigDB lists | CHEN_PDGF_TARGETS | 18 | 7 | 17758 | 2588 |
GOT1,KLF2,KLF9,ZFAND5,TIPARP,LMNA,SGPL1 |
| 1.007e-02 | -4.60 | MODULE_408 | MSigDB lists | MODULE_408 | 18 | 7 | 17758 | 2588 |
ASAH1,PLD1,NAGA,GM2A,PLCG2,HEXB,GPX4 |
| 1.007e-02 | -4.60 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | MSigDB lists | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | 18 | 7 | 17758 | 2588 |
FYN,PIK3CD,YES1,CBL,SYK,PIK3R1,PIK3CA |
| 1.007e-02 | -4.60 | PARK_HSC_VS_MULTIPOTENT_PROGENITORS_UP | MSigDB lists | PARK_HSC_VS_MULTIPOTENT_PROGENITORS_UP | 18 | 7 | 17758 | 2588 |
H2AFY,CAPNS1,CLIP2,TMEM14A,DCUN1D1,PRKAR1A,NFIX |
| 1.007e-02 | -4.60 | NAM_FXYD5_TARGETS_DN | MSigDB lists | NAM_FXYD5_TARGETS_DN | 18 | 7 | 17758 | 2588 |
FXYD5,FTH1,ARL1,AXL,RNF11,APPBP2,MCCC2 |
| 1.007e-02 | -4.60 | BOWIE_RESPONSE_TO_TAMOXIFEN | MSigDB lists | BOWIE_RESPONSE_TO_TAMOXIFEN | 18 | 7 | 17758 | 2588 |
MX1,IRF7,IFIT1,IFIT3,IFI6,STAT1,IRF1 |
| 1.007e-02 | -4.60 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | MSigDB lists | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | 18 | 7 | 17758 | 2588 |
PLCG1,TRIM24,CNTRL,FGFR1OP2,PIK3R1,STAT1,PIK3CA |
| 1.007e-02 | -4.60 | SMID_BREAST_CANCER_LUMINAL_A_DN | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_A_DN | 18 | 7 | 17758 | 2588 |
TOP2A,CENPN,CDC20,NDC80,CDCA3,MYBL2,CDCA8 |
| 1.007e-02 | -4.60 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN | 18 | 7 | 17758 | 2588 |
GALNT3,EGFL7,TGFBR3,CDH1,CYR61,FXYD3,NCS1 |
| 1.007e-02 | -4.60 | BIOCARTA_PTEN_PATHWAY | MSigDB lists | BIOCARTA_PTEN_PATHWAY | 18 | 7 | 17758 | 2588 |
CDKN1B,ILK,AKT1,PTEN,BCAR1,PIK3R1,PIK3CA |
| 1.007e-02 | -4.60 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | MSigDB lists | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | 18 | 7 | 17758 | 2588 |
PRKAA2,CAB39,STRADB,ACACB,PRKAG2,CPT2,PRKAA1 |
| 1.007e-02 | -4.60 | BIOCARTA_MEF2D_PATHWAY | MSigDB lists | BIOCARTA_MEF2D_PATHWAY | 18 | 7 | 17758 | 2588 |
CALM2,HDAC1,CAPN2,CALM3,CAPNS1,CABIN1,CALM1 |
| 1.008e-02 | -4.60 | regulation of epithelial cell migration | biological process | GO:0010632 | 153 | 34 | 16441 | 2455 |
ANXA3,SOX9,GATA3,VASH1,HDAC6,PDGFB,ETS1,EMP2,SRPX2,NRP2,HDAC9,SVBP,PDCD10,ITGA3,SP100,DAB2IP,TACSTD2,EPB41L4B,EPB41L5,AKT1,RGCC,BCAR1,GPLD1,PTGS2,PLCG1,ACVRL1,CORO1C,PRCP,PLPP3,FGF18,EFNA1,ARSB,HSPB1,SEMA3A |
| 1.009e-02 | -4.60 | CAFFAREL_RESPONSE_TO_THC_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_DN | 31 | 10 | 17758 | 2588 |
CALM2,PPIF,ZWINT,CCNA2,CALM1,CALM3,UBAC1,SESN1,HSPA2,CDK1 |
| 1.009e-02 | -4.60 | REACTOME_DAG_AND_IP3_SIGNALING | MSigDB lists | REACTOME_DAG_AND_IP3_SIGNALING | 31 | 10 | 17758 | 2588 |
CALM2,PLCG1,ADRBK1,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PRKAR1A |
| 1.009e-02 | -4.60 | RUFFLE | MSigDB lists | RUFFLE | 31 | 10 | 17758 | 2588 |
ARAP3,S100A11,FGD6,EZR,CTTN,ARF6,BCAR1,MYO5A,S100A6,FGD1 |
| 1.009e-02 | -4.60 | HALLMARK_NOTCH_SIGNALING | MSigDB lists | HALLMARK_NOTCH_SIGNALING | 31 | 10 | 17758 | 2588 |
CCND1,HES1,LFNG,DTX4,CUL1,ARRB1,NOTCH2,NOTCH3,FZD5,FZD7 |
| 1.009e-02 | -4.60 | PID_AVB3_OPN_PATHWAY | MSigDB lists | PID_AVB3_OPN_PATHWAY | 31 | 10 | 17758 | 2588 |
SPP1,RHOA,NFKBIA,PIK3R1,PIK3CA,ITGAV,ILK,BCAR1,FOS,SYK |
| 1.009e-02 | -4.60 | PID_P38_ALPHA_BETA_PATHWAY | MSigDB lists | PID_P38_ALPHA_BETA_PATHWAY | 31 | 10 | 17758 | 2588 |
MAP3K3,FYN,RALB,PAK2,CCM2,PRKG1,DUSP10,MAPK11,YES1,DUSP1 |
| 1.009e-02 | -4.60 | VALK_AML_CLUSTER_3 | MSigDB lists | VALK_AML_CLUSTER_3 | 31 | 10 | 17758 | 2588 |
ENPP4,IL6ST,AIM1,IL17RA,COL4A5,PLS1,BLVRA,SEPP1,SMC4,WBP5 |
| 1.011e-02 | -4.59 | Pept_C1 | smart domains | SM00645 | 13 | 6 | 9131 | 1455 |
CTSL,CTSZ,TINAGL1,CTSC,CTSB,CTSV |
| 1.018e-02 | -4.59 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 185 | 39 | 17758 | 2588 |
NFKBIE,ZNF395,LGALS3,CD63,GNPDA1,GGA1,TMEM55B,SOD2,FTH1,CNTROB,SNN,MAP1LC3B,PHF1,IER3,P4HB,PPME1,PHTF1,ATP13A3,C9orf72,SNX8,PAPD7,PLAUR,STAT4,BNIP3L,SAV1,TXNDC11,CD83,GABARAPL1,CNOT2,CRTC2,ATP1A1,NR1D2,CHMP4B,HMGA1,ATP6V1C1,ZMIZ1,PTGES,MAFF,PHC1 |
| 1.018e-02 | -4.59 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDM_DN | 185 | 39 | 17758 | 2588 |
CDS2,DHPS,PSME2,NDRG1,TAP1,FTH1,PSME1,CD274,RAB6A,CYP39A1,LGALS3BP,HDAC9,KLF3,DNM2,TMEM143,TPST1,TRIM21,ERBB3,PDIA6,SGCB,PSMA5,ELK3,CBX6,FNDC3A,CYFIP2,ALCAM,RANBP9,NMT2,SEC14L2,HLA-B,CASP7,PEX5,DCK,FGF18,FAM3C,CHMP4B,PPP2R3C,POMT1,NCAPG2 |
| 1.018e-02 | -4.59 | GSE22886_NAIVE_CD8_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_UP | 185 | 39 | 17758 | 2588 |
ATP8A1,HLA-F,TSC22D3,SERPINB9,CACNA2D2,BTN3A1,ETS1,C11orf95,LTBP3,MZT2A,TRANK1,PASK,FAM102A,MYLIP,APOBEC3G,CAMK2G,DUSP1,UXT,SYNE2,BTN3A2,EZR,PRKCQ,TCF7,YES1,CYFIP2,ITPR3,STK17B,PLEKHB1,PRIM1,TXK,MAGED2,STK38,INPP4B,TBC1D4,NR3C2,EHD1,FAM134B,CTDSP1,DOCK9 |
| 1.018e-02 | -4.59 | GSE13306_RA_VS_UNTREATED_TREG_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_TREG_UP | 185 | 39 | 17758 | 2588 |
GRN,CCNE2,LAMP1,LZTFL1,MRC2,FAF2,LGR4,CUL4B,IL27RA,DHRS3,CA8,ERP29,NUDT12,RSAD1,NOV,EFR3A,MGAT4A,SRP54,VAT1,RAB20,CTTN,ZMYM1,MED22,CYP26B1,COL6A2,MMD,KIF13A,SAV1,BBS2,GLT8D2,SFXN5,RAB2B,PITX2,MAGED2,PEX5,FAM3C,LTA4H,NRGN,ARNT |
| 1.021e-02 | -4.58 | ELECTRON_TRANSPORT_GO_0006118 | MSigDB lists | ELECTRON_TRANSPORT_GO_0006118 | 50 | 14 | 17758 | 2588 |
DUOX1,ALDH5A1,CYP4F11,DHRS2,CYB5R2,SLC25A13,FDXR,PDIA5,BLVRA,LOXL1,SPR,POR,GPX4,CYP1B1 |
| 1.021e-02 | -4.58 | BECKER_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | BECKER_TAMOXIFEN_RESISTANCE_UP | 50 | 14 | 17758 | 2588 |
MX1,BTG3,NMI,E2F1,IRF2,IFIT1,EGR3,CTSD,SEPP1,CPE,IFI6,LGALS3BP,EBAG9,EPHX1 |
| 1.022e-02 | -4.58 | PID_HIF1_TFPATHWAY | MSigDB lists | PID_HIF1_TFPATHWAY | 65 | 17 | 17758 | 2588 |
PGM1,AKT1,NDRG1,FURIN,ABCG2,ETS1,FOS,FECH,PFKL,GATA2,BHLHE41,ABCB1,CITED2,EGLN3,ARNT,NCOA2,EGLN1 |
| 1.022e-02 | -4.58 | REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | REGULATION_OF_MAP_KINASE_ACTIVITY | 65 | 17 | 17758 | 2588 |
SPRED1,SOD1,ERBB2,PKN1,TRIB2,MAP3K6,EGFR,RGS3,MADD,MAP3K9,MAP3K11,KIAA1804,MDFIC,MAP3K5,CD81,HIPK3,MDFI |
| 1.022e-02 | -4.58 | AKL_HTLV1_INFECTION_DN | MSigDB lists | AKL_HTLV1_INFECTION_DN | 65 | 17 | 17758 | 2588 |
CCNC,PNISR,DENND1B,DUSP4,SDF4,IL17RB,PTGS2,FYN,FRY,CDH1,CDK19,FAM3C,UBE2J1,MAOA,CTSA,MDFIC,PKIA |
| 1.025e-02 | -4.58 | Alkaline_phosphatase_core | interpro domains | IPR017850 | 31 | 10 | 18293 | 2672 |
ENPP4,GNS,ENPP1,ALPP,ARSG,GALNS,ENPP5,ARSB,ARSK,SULF2 |
| 1.025e-02 | -4.58 | Alkaline_Pase-like_a/b/a | interpro domains | IPR017849 | 31 | 10 | 18293 | 2672 |
ENPP4,GNS,ENPP1,ALPP,ARSG,GALNS,ENPP5,ARSB,ARSK,SULF2 |
| 1.029e-02 | -4.58 | positive regulation of proteasomal protein catabolic process | biological process | GO:1901800 | 89 | 22 | 16441 | 2455 |
PLK1,DLGAP5,AKT1,DNAJB2,GCLC,NUB1,PRICKLE1,PSMD10,TRIB2,RNF19B,BCAP31,VCP,RB1,PTEN,PLK2,PSMC2,AURKA,DAB2IP,OSBPL7,PSMC1,ESPL1,SOCS5 |
| 1.030e-02 | -4.58 | aminoglycan biosynthetic process | biological process | GO:0006023 | 110 | 26 | 16441 | 2455 |
CHSY3,B3GALT6,SLC35D2,B3GNT7,B3GNT2,AGRN,HSPG2,XYLT1,SDC4,PXYLP1,B4GALT4,DSE,SDC1,EXT2,CHST2,CHPF,GLCE,HS6ST1,XYLT2,GPC3,CSGALNACT1,B4GAT1,HS3ST3B1,B4GALT3,ST3GAL1,NDST3 |
| 1.032e-02 | -4.57 | CUI_GLUCOSE_DEPRIVATION | MSigDB lists | CUI_GLUCOSE_DEPRIVATION | 60 | 16 | 17758 | 2588 |
GFPT1,TGIF1,PBK,DNAJC3,DNAJB11,PDIA3,ANLN,CDK1,PDIA4,ELF3,CALR,FUT1,SGK3,GOT1,PDIA6,OCLN |
| 1.032e-02 | -4.57 | human chr7p12.1 | chromosome location | human chr7p12.1 | 5 | 3 | 26250 | 2805 |
FIGNL1,SEMA3A,COBL |
| 1.032e-02 | -4.57 | human chr1p35-p34 | chromosome location | human chr1p35-p34 | 5 | 3 | 26250 | 2805 |
TMEM54,FAAH,COL16A1 |
| 1.033e-02 | -4.57 | PID_IL2_1PATHWAY | MSigDB lists | PID_IL2_1PATHWAY | 55 | 15 | 17758 | 2588 |
MAPKAPK2,IRS2,FYN,RHOA,JAK1,PIK3R1,STAT1,PIK3CA,MAPK11,FOS,JAK3,PPP2R5D,SYK,RASA1,SOCS3 |
| 1.033e-02 | -4.57 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | MSigDB lists | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | 55 | 15 | 17758 | 2588 |
PLK1,CEP70,CNTRL,TUBB4B,CENPJ,NEK2,PLK4,TUBG1,PRKAR2B,SSNA1,CEP41,PRKACA,CDK1,TUBA4A,CKAP5 |
| 1.033e-02 | -4.57 | AGTTCTC,MIR-146A,MIR-146B | MSigDB lists | AGTTCTC,MIR-146A,MIR-146B | 55 | 15 | 17758 | 2588 |
DLGAP1,THRB,PHF20L1,ZFX,KCTD15,CASK,PCDH1,IRAK1,PSMD3,VASN,PTGFRN,STX3,PRX,NRP2,KLF7 |
| 1.033e-02 | -4.57 | PPA1 (pyrophosphatase (inorganic) 1) | protein interactions | 5464 | 33 | 11 | 16036 | 2547 |
AKT1,WIPI1,TP53,HDAC1,GLO1,FBXO6,PLIN3,HDAC6,HSPB1,AIP,MTRNR2L1 |
| 1.033e-02 | -4.57 | CDK16 (cyclin-dependent kinase 16) | protein interactions | 5127 | 33 | 11 | 16036 | 2547 |
SEC23A,CDK17,CDK16,CDK18,PKM,PRKACA,PPP2R2D,CDK5R1,LMNA,SH3KBP1,APPBP2 |
| 1.033e-02 | -4.57 | GLOD4 (glyoxalase domain containing 4) | protein interactions | 51031 | 33 | 11 | 16036 | 2547 |
SOD1,DAZAP1,TXN,NR4A1,SERPINB5,GLO1,GOT1,NANS,BCL2L1,PCBP1,HSPB1 |
| 1.038e-02 | -4.57 | THIOL_PROTEASE_ASN | prosite domains | PS00640 | 10 | 5 | 11866 | 1802 |
CTSL,CTSZ,CTSC,CTSB,CTSV |
| 1.043e-02 | -4.56 | PAS | prosite domains | PS50112 | 30 | 10 | 11866 | 1802 |
AHRR,NCOA3,EPAS1,PASK,ARNT2,PER3,AHR,ARNT,NCOA2,PER2 |
| 1.044e-02 | -4.56 | KRAS.DF.V1_DN | MSigDB lists | KRAS.DF.V1_DN | 191 | 40 | 17758 | 2588 |
PRSS8,BCAM,TRAPPC10,SLC25A13,RET,COL4A5,HMGN3,NRP2,SIRPA,PER2,HDAC9,MYO5C,PDGFA,CYP1A1,PHF7,ALG13,FAM63A,IGFBP2,EPB41L4B,SCN2A,ATP2B1,LAMP3,KLK5,PCBP3,TCFL5,SYP,FANCE,STX3,LCP1,DCAF10,PTGS2,TJP3,ETS2,CDK18,KLF11,LSM14B,AHR,COBL,CBX4,RAB3IL1 |
| 1.044e-02 | -4.56 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | 191 | 40 | 17758 | 2588 |
CDK17,ACVR1,NFKBIE,MRPS15,TBC1D1,TSC22D3,DAP,SERPINB9,PBX3,CALM3,EGR3,DHRS3,EXT2,CALM2,FLII,TGFBR3,KCNN4,DAPK1,BCL6,NFKB2,F2R,SEC23A,ALDH2,ERMAP,PSMB4,CALM1,KIAA1109,DNAJB14,H2AFV,MYL12A,PLEKHB1,TXK,BCAR3,PIAS3,STK38,NOD2,SSNA1,GRAMD1C,SLC25A38,ACOT7 |
| 1.044e-02 | -4.56 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP | 191 | 40 | 17758 | 2588 |
INPPL1,TRIM2,RUNX2,HOXB7,PPM1J,ST14,GCAT,DDR1,ECI1,HLA-A,CPNE2,CDH1,CAPG,OSTF1,SPRY2,TMBIM1,GM2A,S100A6,SNX8,FBLN5,KIAA0040,CLSTN1,PGBD1,PCTP,DPYSL4,RHOB,ENPP1,NAAA,BANK1,C2orf70,PVRL2,SPINT2,NXPH4,NRG1,SERPINB6,EFNA1,PIEZO1,MAP3K5,ARSB,ACOT7 |
| 1.044e-02 | -4.56 | GSE3982_MAST_CELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_NEUTROPHIL_DN | 191 | 40 | 17758 | 2588 |
ARAP3,FLOT1,EFHD2,BTN3A1,SAMD9,PRR7,UHRF1BP1L,HDAC9,VASP,TRANK1,CTGF,CYP4F11,FAM63A,AOX1,BCL6,ADAM15,ABCD1,PIM1,ETV7,CDKN2D,CTDSP2,XKR8,MBP,TRIM8,SYNE2,DOCK5,HNRNPH2,PRCP,SH2D3C,TMC5,ARAP1,ZNF165,DHTKD1,ADIPOR1,CABIN1,SLC31A2,F2RL1,IFIH1,HOOK1,CSRP2 |
| 1.047e-02 | -4.56 | gamma-tubulin complex | cellular component | GO:0000930 | 18 | 7 | 17570 | 2579 |
TUBG1,MZT2A,MZT1,CENPJ,UXT,TUBGCP6,CKAP5 |
| 1.053e-02 | -4.55 | MyD88-independent toll-like receptor signaling pathway | biological process | GO:0002756 | 84 | 21 | 16441 | 2455 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,NFKBIA,UBE2D2,NOD2,MAPK11,IRF7,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 1.053e-02 | -4.55 | myelination | biological process | GO:0042552 | 84 | 21 | 16441 | 2455 |
SOD1,MBP,UGT8,AKT1,NDRG1,HEXB,ERBB2,KLK6,MPP5,ILK,DAG1,CNTNAP1,TSC1,FA2H,PTEN,NAB2,CD9,ERCC2,SCN2A,PIKFYVE,MYO5A |
| 1.053e-02 | -4.55 | metanephros development | biological process | GO:0001656 | 84 | 21 | 16441 | 2455 |
HES1,NKX3-1,LGR4,FMN1,RET,SOX9,GATA3,OSR2,PDGFB,SIX4,IRX3,CTNNB1,GPC3,FRAS1,BMP7,STAT1,SMO,PKD2,GDF11,SOX8,OSR1 |
| 1.053e-02 | -4.55 | human chr11q14 | chromosome location | human chr11q14 | 9 | 4 | 26250 | 2805 |
RAB38,POLD3,PRCP,SYTL2 |
| 1.053e-02 | -4.55 | human chr9p22.3 | chromosome location | human chr9p22.3 | 9 | 4 | 26250 | 2805 |
SMARCA2,TTC39B,PSIP1,ZDHHC21 |
| 1.054e-02 | -4.55 | activation of GTPase activity | biological process | GO:0090630 | 35 | 11 | 16441 | 2455 |
ARHGAP24,TSC1,RASGRF1,CORO1C,SIPA1L1,TAX1BP3,SCRIB,EPHA1,ARHGEF16,RASGRP1,SYDE2 |
| 1.054e-02 | -4.55 | V$CEBPB_01 | MSigDB lists | V$CEBPB_01 | 249 | 50 | 17758 | 2588 |
PLA2G4A,NCKAP5,BMF,PHOSPHO1,CCNL1,FAM91A1,BAHD1,ZFYVE9,NRP2,SLC25A35,FOXP2,RGS3,LMO4,MITF,FBXL14,GYS1,HEXIM2,PIM1,FLOT2,FAR1,PLCB2,TBC1D10B,DUSP1,PDGFC,DCAF6,CASK,WNT10B,MOSPD2,CAPN6,CTNNAL1,PIK3R1,RC3H2,BNIP3L,VAMP3,ITPR3,SPTLC2,PCTP,RHOB,PRDX4,MAGED2,LEMD2,PITX2,PPP1CB,KLF5,STK39,SPRY4,CEP41,GEN1,TOB1,CBX4 |
| 1.054e-02 | -4.55 | sarcolemma | cellular component | GO:0042383 | 112 | 26 | 17570 | 2579 |
LAMP1,BIN1,SCN5A,SGCE,SLC2A4,COL6A2,CTSB,UTRN,FLOT1,EZR,PRKCQ,ATP1B1,SNTB1,SLC8B1,DAG1,SNTA1,ANK1,ATP1A1,SLC27A6,ITGA7,COL6A1,DLG1,DYSF,CACNA1D,SCN2A,SGCB |
| 1.060e-02 | -4.55 | human chr6q15 | chromosome location | human chr6q15 | 24 | 7 | 26250 | 2805 |
CFAP206,PM20D2,MAP3K7,ANKRD6,SLC35A1,UBE2J1,RRAGD |
| 1.061e-02 | -4.55 | PID_CXCR4_PATHWAY | MSigDB lists | PID_CXCR4_PATHWAY | 102 | 24 | 17758 | 2588 |
RHOA,SSH1,AKT1,INPP5D,ITCH,ITGA6,PIK3R1,VPS4B,YES1,GRK6,BCAR1,RHOB,FYN,ITGA3,ADRBK1,PTEN,RALB,ITGA7,LIMK1,STAT1,PIK3CA,PIK3CD,ITGAV,PLCB2 |
| 1.062e-02 | -4.55 | blood_vessel | COSMIC cancer mutations | blood_vessel | 2302 | 372 | 17775 | 2585 |
FAM171B,ADD1,LGR4,SSH1,AASS,SLC25A13,ATP8A1,TSC22D3,DNAJC3,HEXB,RET,PPFIBP2,TRAPPC8,SYTL4,PLXNA1,SEPT4,CA8,SLC9A7,CYP1A1,DNAH6,AOX1,PIK3CA,ATRNL1,SNX16,TIAM1,MGAT5,NBPF3,TNS1,PPP1R14C,CCNF,MYOM1,POR,COL12A1,AHRR,KDSR,PLCG1,DNM1L,ATP7B,MYLK,PRDM5,FAM110C,TANC2,TRAF5,GAB1,KLF2,FRMD4A,ALDH6A1,TBC1D1,KIF23,SLC36A4,SLC1A3,NOTCH2,APBA1,FAM21C,PDXDC1,MECOM,RALGPS2,FRY,FAM189A1,BDH1,MSH2,PRKG1,MAP3K9,SORL1,CADPS2,STT3B,CACNA1D,KCTD3,RIMS2,MCCC2,TMED2,PAQR7,EPB41L5,PIGC,STAT4,GNA11,SLCO4A1,AP1AR,PRKAG2,PLEKHH2,HTT,FAAH,PCDH19,IFIH1,RPS6KA3,XDH,ADAMTS16,WDR63,PLA2G4A,TCTN2,FAM131C,IQGAP1,APOO,PKP2,RNF182,GRK6,CD274,FAM91A1,FLT3,APC2,TNFSF9,KIAA1147,ZNF385B,UHRF1BP1L,RCN1,MUC16,RNF220,ACAP2,CDH1,RTKN2,MYO5B,SNX8,CDKN2AIP,ERMP1,COG2,AGPS,PTPN9,SYNE2,CLSTN1,UTRN,TEP1,TANC1,ITPR3,ALCAM,TRIQK,ATP10D,NIN,CMTM7,CCNB3,CDK19,ZNF704,PLEKHG1,HS3ST3B1,NR3C2,COBL,MAMDC2,DENND5B,FARP1,TAOK2,FAM189A2,PARP14,CCM2,EPS8,DNAH3,SRPX2,HOXB2,PDCD10,TMEM87B,ITGB8,ANKS1B,ARSG,PTEN,TUBGCP6,FUT8,ATP8B1,FAM102A,TTPA,TRIM62,NCOA2,PCCB,PDGFC,ARHGEF28,CTNNAL1,TCFL5,MRS2,PIK3R1,PLEKHA7,DIAPH2,C2orf69,RAB3IP,AIF1L,SNTB1,ABLIM2,GALNT3,RGS9,PROM1,LDLRAP1,FGFR2,SLC35B3,PPM1H,GRIN2D,ITGAV,CD81,ARSB,USF2,ESPL1,PHC1,RGMA,JARID2,LTBP1,ARFGEF1,TEX2,NENF,MPP5,ITPR2,NUP62CL,DNER,CACNB4,KREMEN1,TMC1,NKAIN3,SIPA1L2,HSF2,CTNNB1,SHC3,PAPSS1,ANKFN1,PHTF1,SLC44A1,POF1B,TRPC1,RGS5,ARNT2,ANO4,MYRIP,TRAM1,ZNF462,TDP1,MARK1,ASXL1,RNF165,CR2,IDH1,CLCN2,ADRBK2,DZIP1L,PI4K2B,KCNMB4,HPSE,MAP2,HOXA9,IARS2,EPB41L4A,APBA2,TC2N,CPPED1,HS6ST3,PPP1R12A,ZCCHC24,UBASH3B,ABCG2,CALM3,CNTNAP2,PHLPP1,DOCK11,RSAD1,PGAP1,MYO5C,TNS3,DAZAP1,IGF1R,FAM20C,FRAS1,PRKCI,MDFIC,LIMCH1,KNTC1,PIM1,ZRANB1,ALDH3A2,CHSY3,WDR72,USP31,CORO2A,MGAT4B,KBTBD8,PDE5A,EIF2AK1,KIAA1109,SCRIB,HEATR5A,MFSD7,EGFR,NMT2,RHPN1,GNAS,TSC1,ONECUT1,PHLPP2,CGREF1,PITPNA,PLD1,ZDBF2,USP43,LMO7,GAS2L1,NCKAP5,XYLT1,TP53,PDIA5,P2RX7,ERBB2,RHPN2,PATL2,PER2,CDK14,SLC25A48,CDH3,DIXDC1,NOTCH3,FAR1,UPF3A,EBAG9,CPD,TMTC1,CLCN3,AKT1,PTPRU,SLC39A8,TMTC2,DUSP4,DOCK5,FANCE,PDHX,DNAJC10,PTPRJ,C19orf66,ABHD12,STAT6,TLE1,RCAN2,EFNA5,SPTBN5,PLXND1,CYP2U1,LTA4H,COL9A3,PACSIN2,GOLIM4,CDH22,ARHGEF11,SCD5,GNAL,MCTP2,LRP4,ERCC6L,MIER3,NOTUM,FZD6,SLC9A2,PPP2R3A,CEP97,MLPH,MAGEE1,BMP7,TOX2,KIAA0319,IL17RA,H2AFY,BUB1,IQGAP3,MYO5A,HMMR,DLGAP1,FBLN5,DEPDC4,GCLC,RC3H2,MAML2,FNDC3A,POLD3,MAP1B,ARHGAP24,BANK1,RAP2C,CLIP4,UACA,PPP2R3C,GRAMD1C,TBC1D4,AHR,L1CAM |
| 1.063e-02 | -4.54 | CDC42 (cell division cycle 42) | protein interactions | 998 | 176 | 40 | 16036 | 2547 |
CASP3,ST13,ARHGEF11,TRIP10,SH3D19,TRAF2,IQGAP1,ARHGEF7,TP53,CBLL1,TGFBR1,NOTCH2,KTN1,SSX2IP,PAK6,RAC2,CDH1,MCF2L,OCRL,PAK2,PRKCI,LRIF1,METAP2,TCEB2,PIK3R1,DIAPH2,ARHGDIB,CBL,BCAR1,ARHGAP35,USP6,CASP7,MAP3K11,ARRB1,PLD1,RPL22,ABCA1,DEF6,FGD1,DOCK9 |
| 1.068e-02 | -4.54 | GSE20715_0H_VS_24H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_24H_OZONE_LUNG_DN | 197 | 41 | 17758 | 2588 |
SORBS1,CDKN1C,BIK,SOD2,GDF15,BCL2L1,MERTK,ADAMTSL4,EFNB1,CARD10,GBX2,ELF3,CAPN2,SPP1,TIMP1,FABP6,PLK4,DAPK1,KLF9,TINAGL1,MANF,CPE,CTH,CKS2,FURIN,SCRIB,RAB3IP,NPC2,DOCK5,MAP3K6,TCN2,BCAR3,RBM47,KLF12,AREG,KCNK1,OSMR,CDK18,RCAN2,SPCS3,MAFF |
| 1.073e-02 | -4.53 | negative regulation of lipid metabolic process | biological process | GO:0045833 | 79 | 20 | 16441 | 2455 |
CCNC,SIRT1,ACACB,SOD1,AKT1,PRKAA1,WDTC1,PDGFB,FGF19,PLIN5,GPLD1,PDGFA,BMP2,ATP1A1,PPP2R5A,ADORA1,SLC27A1,DAB2IP,GPER1,GFI1 |
| 1.073e-02 | -4.53 | nephron tubule development | biological process | GO:0072080 | 79 | 20 | 16441 | 2455 |
HES1,LGR4,FMN1,SOX9,DCHS1,GATA3,ILK,IRX3,BMP2,CTNNBIP1,FAT4,CTNNB1,NPNT,GPC3,DLG1,PKD2,TACSTD2,SOX8,OSR1,ADAMTS16 |
| 1.079e-02 | -4.53 | PPP3CA (protein phosphatase 3, catalytic subunit, alpha isozyme) | protein interactions | 5530 | 65 | 18 | 16036 | 2547 |
CASP3,SOD1,KCNIP3,AKT1,TP53,GABRG2,VCP,C16orf74,CRTC2,PTEN,PHLPP2,IRF2,CABIN1,RCAN2,PDE4D,RCAN3,MAPK7,PDIA6 |
| 1.080e-02 | -4.53 | PID | pfam domains | PF00640 | 26 | 9 | 16629 | 2504 |
LDLRAP1,TBC1D1,SHC3,ANKS1B,APPL2,APBA1,APBA2,TBC1D4,MAPK8IP1 |
| 1.081e-02 | -4.53 | temporooccipital | COSMIC cancer mutations | temporooccipital | 7 | 4 | 17775 | 2585 |
CDKN2C,CTNNB1,IDH1,TP53 |
| 1.081e-02 | -4.53 | neuronal_tumour | COSMIC cancer mutations | neuronal_tumour | 7 | 4 | 17775 | 2585 |
ERBB2,AKT1,EGFR,PIK3CA |
| 1.081e-02 | -4.53 | central_nervous_system-brain-glioma-subependymoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-subependymoma_Grade_I | 7 | 4 | 17775 | 2585 |
NF2,IDH1,PTEN,TP53 |
| 1.081e-02 | -4.53 | subependymoma_Grade_I | COSMIC cancer mutations | subependymoma_Grade_I | 7 | 4 | 17775 | 2585 |
NF2,IDH1,PTEN,TP53 |
| 1.081e-02 | -4.53 | bone-vertebrae-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-vertebrae-chondrosarcoma-dedifferentiated | 7 | 4 | 17775 | 2585 |
IDH1,EGFR,PIK3CA,TP53 |
| 1.081e-02 | -4.53 | cervix-carcinoma-endometrioid_adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-endometrioid_adenocarcinoma | 7 | 4 | 17775 | 2585 |
GNAS,PTEN,PIK3CA,TP53 |
| 1.081e-02 | -4.53 | bone-chest_wall-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-chest_wall-chondrosarcoma-dedifferentiated | 7 | 4 | 17775 | 2585 |
IDH1,EGFR,PIK3CA,TP53 |
| 1.081e-02 | -4.53 | central_nervous_system-temporal_lobe-neuronal_tumour | COSMIC cancer mutations | central_nervous_system-temporal_lobe-neuronal_tumour | 7 | 4 | 17775 | 2585 |
ERBB2,AKT1,EGFR,PIK3CA |
| 1.081e-02 | -4.53 | bone-radius-chondrosarcoma-conventional | COSMIC cancer mutations | bone-radius-chondrosarcoma-conventional | 7 | 4 | 17775 | 2585 |
IDH1,EGFR,PIK3CA,TP53 |
| 1.082e-02 | -4.53 | regulation of mononuclear cell proliferation | biological process | GO:0032944 | 187 | 40 | 16441 | 2455 |
CASP3,LGALS3,DHPS,IL15,INPP5D,HLA-E,ERBB2,IL18,CD274,PKN1,TNFSF9,EFNB1,HLA-A,CD46,RAC2,CTNNB1,IL6ST,BCL6,DLG1,IGFBP2,C10orf54,WNT3A,SLC39A10,SYK,HES1,CD55,RIPK2,ITCH,PDE5A,PRKCQ,CD40,IRS2,CSF1,ICOSLG,CD81,NDFIP1,JAK3,AHR,PRKAR1A,IRF1 |
| 1.083e-02 | -4.53 | DAIRKEE_TERT_TARGETS_DN | MSigDB lists | DAIRKEE_TERT_TARGETS_DN | 113 | 26 | 17758 | 2588 |
PACSIN2,BCL9,DENND1B,STAU2,LMCD1,TRAPPC8,HES2,MGAT5B,KIF26A,AMDHD1,ARHGEF26,ZFYVE16,B3GALNT1,SPIN3,ACAP2,GATA2,CALD1,DACT1,UBE2J1,PPM1H,SH3BGRL2,EFNA5,PLXND1,STARD13,KANK3,CMTM4 |
| 1.083e-02 | -4.53 | GSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_DN | 180 | 38 | 17758 | 2588 |
UGT8,UGP2,ADD1,JRKL,DGKQ,SELL,NES,BLCAP,DENND2D,SCML1,MYO5C,AP1M2,ST5,IL6ST,ICAM5,MSH2,SORL1,DIXDC1,KLF9,ECE1,PPP6R1,CRTAP,ABCC1,POU6F1,BCL9,TNS1,EPHA1,TXK,LDLRAP1,ATP1A1,AREG,SH3BP4,CLMN,RAP1GAP,APBA2,TRAF5,KLF7,TLL2 |
| 1.084e-02 | -4.52 | mucoepidermoid_carcinoma | COSMIC cancer mutations | mucoepidermoid_carcinoma | 97 | 23 | 17775 | 2585 |
BIN1,LRRFIP2,CHCHD7,TP53,ERBB2,C12orf65,TRAPPC8,ERBB2IP,PRKRA,EGFR,TSEN34,KIF5B,MMP15,KIAA1107,CDH1,CTNNB1,PTEN,CCDC6,ZDHHC20,PIK3CA,GLB1,TINAGL1,KDELC2 |
| 1.084e-02 | -4.52 | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN | MSigDB lists | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN | 135 | 30 | 17758 | 2588 |
NUDT6,PDGFC,PRSS23,EPAS1,EPHA4,ERBB2,NOTCH2,EPHA1,RHOB,NRP2,FZD7,EPHA10,CALR,MDK,BTG1,TYMP,TIMP3,CTGF,PTEN,FGFR2,SERPINB5,TNFRSF12A,EFNA5,DIXDC1,EPHB4,NOTCH3,FZD5,F2RL1,DVL2,FRS3 |
| 1.084e-02 | -4.52 | RB_P107_DN.V1_UP | MSigDB lists | RB_P107_DN.V1_UP | 135 | 30 | 17758 | 2588 |
CCNE2,COL6A2,PCOLCE,FBLN5,CDKN1C,TCFL5,S100A4,BLVRB,CCNF,H2AFV,BEX2,SRPX2,LGALS3BP,GINS4,H1FX,PRDX4,PRIM1,PCNA,CA2,SIVA1,COL6A1,E2F1,PRC1,TUBG1,ETHE1,LOXL1,CD81,E2F8,COL16A1,DUSP1 |
| 1.085e-02 | -4.52 | peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | peripheral_T_cell_lymphoma_unspecified | 169 | 36 | 17775 | 2585 |
NCKAP5,CPEB4,RUSC2,EPS8,SMARCAL1,TP53,KIF23,ITPR2,FLT3,S100A2,CDKN2C,RB1,CTNNB1,PTEN,TACC2,DNM2,PIK3CA,AKR1B1,LIMCH1,EPHB4,ODF2L,SYTL3,HP1BP3,RHOA,AURKB,CBL,IDH1,ADRBK2,SOX13,SOCS3,PLCG1,FYN,TMEM30A,SLC9A6,NKD1,STAT1 |
| 1.085e-02 | -4.52 | acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | acute_myeloid_leukaemia_therapy_related | 1584 | 262 | 17775 | 2585 |
TRIM24,SLC25A13,ATP8A1,CACNA2D2,ARHGAP42,IQCE,OSBPL3,IL31RA,SERINC2,ATRNL1,SNX16,SNTB2,HSPA12A,NBPF3,AURKB,LDB2,MYOM1,PNKD,COL12A1,ENPP1,TBX1,PRDM5,TANC2,UNC5B,RTN3,ANXA11,FRMD4A,GGA1,CYP2J2,CALB2,SLC1A3,NOTCH2,APBA1,PDXDC1,RAVER2,FRY,FAM189A1,AIM1,PRKG1,SLAIN2,CADPS2,STT3B,NCAM1,DGKG,FAM69A,EPB41L5,QSOX1,KLK5,MFI2,TBC1D8B,MYBL2,GLT8D2,CYB5A,STX3,PDE11A,IL1R1,CACHD1,TJP3,FGD6,CLMN,OSMR,CABIN1,KLK7,PER3,HOOK1,XDH,PKD1L2,WDR63,PLA2G4A,MTM1,RGS20,ETNK1,FAM91A1,FLT3,CYP39A1,ZNF385B,ZNF75D,ACAP2,RTKN2,OSBPL7,FLOT2,SCN3A,MYO5B,RIPK2,COG2,CAPN6,SEPT6,SYNE2,PANK1,UTRN,CBL,TANC1,AKR1E2,NIN,SPIN3,JAK1,SHROOM3,WFS1,INPP4B,NRG1,NR3C2,MAMDC2,DENND5B,OTUD5,TTC8,WASF3,FARP1,NES,SEPP1,TMEM87B,ITGB8,RNF128,ANKS1B,KNDC1,CALD1,CD9,CASK,FMN1,PLEKHA7,DIAPH2,UBAC1,LRRC1,GRTP1,KIF11,C4orf27,GALNT3,RGS9,PROM1,SYT7,CCDC6,CMPK2,SHOX2,JARID2,LTBP1,UGT8,LMCD1,MCCC1,FHDC1,UBE2Z,TEX2,ITPR2,DNER,SPTB,TMC1,SH3KBP1,NKAIN3,SIPA1L2,TM9SF2,DPYSL2,ANKFN1,CAPG,TRPC1,RAB20,RP2,MYH14,ARNT2,MYRIP,ZNF462,MARK1,MCTP1,ASXL1,ERP44,ROR1,SESN1,IDH1,STK17B,VCP,HS6ST1,WIPI1,MAP2,EPB41L4A,RRAGD,HS6ST3,USH1C,PPP1R12A,ZCCHC24,RASA2,CNTNAP2,FBLN1,DHRS3,B4GALNT1,TNS3,DAZAP1,CA2,FRAS1,SLC30A6,LIMCH1,C10orf54,NTN1,MPHOSPH9,ELK3,PDE5A,BTN3A2,KIAA1109,EGFR,XKRX,BCAR3,FA2H,P4HA3,ALPK3,ATP1B3,CDAN1,SEMA3A,SHROOM2,LMO7,NCKAP5,PAX6,XYLT1,TP53,COL18A1,CCNL1,CDK14,ZNF687,SRPX,TACC2,FRYL,RPN2,EPB41L4B,SULF2,TMTC2,DOCK5,IDE,EFNA5,SPTBN5,SYT13,LTA4H,NDST3,BIN1,CMAS,SORT1,TSPAN15,ARHGEF11,DAP,POC1B,LRP4,CDCA8,MIER3,GTF3A,TGFBR1,LBR,PPP2R3A,CD109,SNX13,ADORA1,BMP7,H2AFY,IGDCC4,DLGAP1,P2RX4,SYBU,MBNL3,TRIM35,MAML2,MAP1B,CNOT2,DDAH1,BANK1,C2orf70,FAM117A,PTGES,NGEF,ABCG1 |
| 1.085e-02 | -4.52 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | 1584 | 262 | 17775 | 2585 |
TRIM24,SLC25A13,ATP8A1,CACNA2D2,ARHGAP42,IQCE,OSBPL3,IL31RA,SERINC2,ATRNL1,SNX16,SNTB2,HSPA12A,NBPF3,AURKB,LDB2,MYOM1,PNKD,COL12A1,ENPP1,TBX1,PRDM5,TANC2,UNC5B,RTN3,ANXA11,FRMD4A,GGA1,CYP2J2,CALB2,SLC1A3,NOTCH2,APBA1,PDXDC1,RAVER2,FRY,FAM189A1,AIM1,PRKG1,SLAIN2,CADPS2,STT3B,NCAM1,DGKG,FAM69A,EPB41L5,QSOX1,KLK5,MFI2,TBC1D8B,MYBL2,GLT8D2,CYB5A,STX3,PDE11A,IL1R1,CACHD1,TJP3,FGD6,CLMN,OSMR,CABIN1,KLK7,PER3,HOOK1,XDH,PKD1L2,WDR63,PLA2G4A,MTM1,RGS20,ETNK1,FAM91A1,FLT3,CYP39A1,ZNF385B,ZNF75D,ACAP2,RTKN2,OSBPL7,FLOT2,SCN3A,MYO5B,RIPK2,COG2,CAPN6,SEPT6,SYNE2,PANK1,UTRN,CBL,TANC1,AKR1E2,NIN,SPIN3,JAK1,SHROOM3,WFS1,INPP4B,NRG1,NR3C2,MAMDC2,DENND5B,OTUD5,TTC8,WASF3,FARP1,NES,SEPP1,TMEM87B,ITGB8,RNF128,ANKS1B,KNDC1,CALD1,CD9,CASK,FMN1,PLEKHA7,DIAPH2,UBAC1,LRRC1,GRTP1,KIF11,C4orf27,GALNT3,RGS9,PROM1,SYT7,CCDC6,CMPK2,SHOX2,JARID2,LTBP1,UGT8,LMCD1,MCCC1,FHDC1,UBE2Z,TEX2,ITPR2,DNER,SPTB,TMC1,SH3KBP1,NKAIN3,SIPA1L2,TM9SF2,DPYSL2,ANKFN1,CAPG,TRPC1,RAB20,RP2,MYH14,ARNT2,MYRIP,ZNF462,MARK1,MCTP1,ASXL1,ERP44,ROR1,SESN1,IDH1,STK17B,VCP,HS6ST1,WIPI1,MAP2,EPB41L4A,RRAGD,HS6ST3,USH1C,PPP1R12A,ZCCHC24,RASA2,CNTNAP2,FBLN1,DHRS3,B4GALNT1,TNS3,DAZAP1,CA2,FRAS1,SLC30A6,LIMCH1,C10orf54,NTN1,MPHOSPH9,ELK3,PDE5A,BTN3A2,KIAA1109,EGFR,XKRX,BCAR3,FA2H,P4HA3,ALPK3,ATP1B3,CDAN1,SEMA3A,SHROOM2,LMO7,NCKAP5,PAX6,XYLT1,TP53,COL18A1,CCNL1,CDK14,ZNF687,SRPX,TACC2,FRYL,RPN2,EPB41L4B,SULF2,TMTC2,DOCK5,IDE,EFNA5,SPTBN5,SYT13,LTA4H,NDST3,BIN1,CMAS,SORT1,TSPAN15,ARHGEF11,DAP,POC1B,LRP4,CDCA8,MIER3,GTF3A,TGFBR1,LBR,PPP2R3A,CD109,SNX13,ADORA1,BMP7,H2AFY,IGDCC4,DLGAP1,P2RX4,SYBU,MBNL3,TRIM35,MAML2,MAP1B,CNOT2,DDAH1,BANK1,C2orf70,FAM117A,PTGES,NGEF,ABCG1 |
| 1.088e-02 | -4.52 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma | 36 | 11 | 17775 | 2585 |
GNAS,RB1,CTNNB1,PTEN,AMER1,MSH2,PIK3CA,TP53,IDH1,EGFR,PRKAR1A |
| 1.088e-02 | -4.52 | central_nervous_system-thalamus-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-astrocytoma_Grade_I | 36 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,RET,TP53,SMO,PIK3CA,IDH1,GNA11,EGFR |
| 1.089e-02 | -4.52 | ERAD pathway | biological process | GO:0036503 | 74 | 19 | 16441 | 2455 |
UFD1L,SEC61B,FAF2,ERLEC1,HSP90B1,DNAJB2,JKAMP,AMFR,FBXO2,FBXO6,VCP,DNAJB9,DNAJC10,WFS1,PSMC2,UBE2J1,YOD1,STT3B,PSMC1 |
| 1.089e-02 | -4.52 | positive regulation of DNA replication | biological process | GO:0045740 | 74 | 19 | 16441 | 2455 |
PDGFC,GRHL2,PRKCQ,AURKB,PDGFB,PARM1,EGFR,CALR,PDGFA,NPM2,E2F7,INSR,PCNA,IGF1R,CTNNB1,AREG,CST3,NEK2,E2F8 |
| 1.089e-02 | -4.52 | positive regulation of adaptive immune response | biological process | GO:0002821 | 74 | 19 | 16441 | 2455 |
SIRT1,RIPK2,HLA-E,TRAF2,WHSC1,P2RX7,IL27RA,PRKCQ,CD40,HLA-A,HLA-B,PVRL2,IL6ST,STAT6,NOD2,FZD5,MAP3K7,MSH6,SOCS5 |
| 1.089e-02 | -4.52 | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_DN | 7 | 4 | 17758 | 2588 |
TLE1,TRIM8,CAST,SOX9 |
| 1.089e-02 | -4.52 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7 | 7 | 4 | 17758 | 2588 |
RPL22,PIK3CA,MECOM,BCL6 |
| 1.089e-02 | -4.52 | BUSA_SAM68_TARGETS_UP | MSigDB lists | BUSA_SAM68_TARGETS_UP | 7 | 4 | 17758 | 2588 |
CCND1,MAPK11,NR3C1,NR4A1 |
| 1.089e-02 | -4.52 | SCHRAMM_INHBA_TARGETS_UP | MSigDB lists | SCHRAMM_INHBA_TARGETS_UP | 7 | 4 | 17758 | 2588 |
CCND1,DUSP4,LMO4,BAX |
| 1.090e-02 | -4.52 | VERHAAK_GLIOBLASTOMA_NEURAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_NEURAL | 124 | 28 | 17758 | 2588 |
ENPP4,ANXA3,MBP,UGT8,MMD,REPS2,CRYM,LYRM1,NDRG2,TMEM144,MORF4L2,SEPP1,HPCAL4,RND1,ADD3,PPP2R5A,POPDC3,ANKS1B,KCNK1,SGK3,ATRNL1,ARRB1,SERPINI1,MDH1,ACSL4,TTPA,SLC31A2,CAMK2G |
| 1.091e-02 | -4.52 | KIM_WT1_TARGETS_12HR_DN | MSigDB lists | KIM_WT1_TARGETS_12HR_DN | 203 | 42 | 17758 | 2588 |
CCNE2,NF2,SSH1,SOD2,IL18,KBTBD11,ARHGEF40,ETS1,PHLDA1,COX7A2,CCND1,CTGF,CYR61,CALD1,ELF5,GTF2F2,LIMCH1,MANF,RIMS2,TMED2,SMAGP,IGSF3,DUSP1,ELK3,PLSCR1,EZR,ARFRP1,ZFAND5,SPTLC2,STEAP1,CASP4,CDK5R1,EGFR,PLOD2,RND3,CORO1C,PLK2,RAP2C,FAM3C,TMC5,PPP1CB,NRG1 |
| 1.095e-02 | -4.51 | positive regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070304 | 132 | 30 | 16441 | 2455 |
MAP3K3,TAOK2,RIPK2,FZD4,TRAF2,EPHA4,PKN1,FGF19,MAP3K6,FZD7,BMP2,PDCD10,CTGF,ANKRD6,KIAA1804,MAP3K9,MAP3K11,NOD2,DAB2IP,MDFIC,FZD5,MAP3K5,MAP3K7,F2RL1,SYK,GAB1,RASGRP1,DVL2,MDFI,XDH |
| 1.095e-02 | -4.51 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-poorly_differentiated | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-poorly_differentiated | 4 | 3 | 17775 | 2585 |
SS18,CTNNB1,PTEN |
| 1.095e-02 | -4.51 | central_nervous_system-parietooccipital-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-parietooccipital-primitive_neuroectodermal_tumour-medulloblastoma | 4 | 3 | 17775 | 2585 |
CTNNB1,IDH1,TP53 |
| 1.095e-02 | -4.51 | kidney-Wilms_tumour-unilateral | COSMIC cancer mutations | kidney-Wilms_tumour-unilateral | 4 | 3 | 17775 | 2585 |
CTNNB1,AMER1,TP53 |
| 1.095e-02 | -4.51 | endometrium-hyperplasia-complex | COSMIC cancer mutations | endometrium-hyperplasia-complex | 4 | 3 | 17775 | 2585 |
CTNNB1,PTEN,PIK3CA |
| 1.095e-02 | -4.51 | central_nervous_system-frontoparietal-other-dysembryoplastic_neuroepithelial_tumour | COSMIC cancer mutations | central_nervous_system-frontoparietal-other-dysembryoplastic_neuroepithelial_tumour | 4 | 3 | 17775 | 2585 |
IDH1,EGFR,TP53 |
| 1.095e-02 | -4.51 | soft_tissue-blood_vessel-haemangioma-spindle_cell | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma-spindle_cell | 4 | 3 | 17775 | 2585 |
GNAS,IDH1,PIK3CA |
| 1.095e-02 | -4.51 | unilateral | COSMIC cancer mutations | unilateral | 4 | 3 | 17775 | 2585 |
CTNNB1,AMER1,TP53 |
| 1.095e-02 | -4.51 | complex | COSMIC cancer mutations | complex | 4 | 3 | 17775 | 2585 |
CTNNB1,PTEN,PIK3CA |
| 1.095e-02 | -4.51 | central_nervous_system-temporal_lobe-glioma-oligoastrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-oligoastrocytoma_Grade_II | 4 | 3 | 17775 | 2585 |
CDKN2C,IDH1,PTEN |
| 1.095e-02 | -4.51 | ependymoblastoma_Grade_IV | COSMIC cancer mutations | ependymoblastoma_Grade_IV | 4 | 3 | 17775 | 2585 |
CTNNB1,PTEN,TP53 |
| 1.095e-02 | -4.51 | poorly_differentiated | COSMIC cancer mutations | poorly_differentiated | 4 | 3 | 17775 | 2585 |
SS18,CTNNB1,PTEN |
| 1.095e-02 | -4.51 | meninges-meningioma-rhabdoid | COSMIC cancer mutations | meninges-meningioma-rhabdoid | 4 | 3 | 17775 | 2585 |
NF2,AKT1,IDH1 |
| 1.095e-02 | -4.51 | normal-like_carcinoma | COSMIC cancer mutations | normal-like_carcinoma | 4 | 3 | 17775 | 2585 |
CDH1,PIK3CA,TP53 |
| 1.095e-02 | -4.51 | breast-carcinoma-normal-like_carcinoma | COSMIC cancer mutations | breast-carcinoma-normal-like_carcinoma | 4 | 3 | 17775 | 2585 |
CDH1,PIK3CA,TP53 |
| 1.095e-02 | -4.51 | salivary_gland-parotid-carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma | 4 | 3 | 17775 | 2585 |
EGFR,PIK3CA,TP53 |
| 1.095e-02 | -4.51 | adrenal_gland-adrenal_gland-adrenal_cortical_neoplasm-aldosterone_producing | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_neoplasm-aldosterone_producing | 4 | 3 | 17775 | 2585 |
GNAS,CTNNB1,TP53 |
| 1.095e-02 | -4.51 | upper_aerodigestive_tract-head_neck-other-dysplasia | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-other-dysplasia | 4 | 3 | 17775 | 2585 |
PTEN,EGFR,TP53 |
| 1.095e-02 | -4.51 | lung-left_lower_lobe-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-left_lower_lobe-carcinoma-bronchioloalveolar_adenocarcinoma | 4 | 3 | 17775 | 2585 |
ERBB2,EGFR,TP53 |
| 1.095e-02 | -4.51 | central_nervous_system-temporooccipital-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-temporooccipital-primitive_neuroectodermal_tumour-medulloblastoma | 4 | 3 | 17775 | 2585 |
CTNNB1,IDH1,TP53 |
| 1.096e-02 | -4.51 | V$LMO2COM_02 | MSigDB lists | V$LMO2COM_02 | 232 | 47 | 17758 | 2588 |
GAS2L1,BIN1,CMAS,CPEB4,SLC41A1,CAST,C6orf106,NDRG2,ISYNA1,CAMK1D,PKN1,ZNF219,FAM101B,SPTB,NRP2,PPP2R3A,ARHGEF10L,FOXP2,ANKS1B,LHX6,MITF,BCL6,WBP4,KRT80,TACC1,FZD4,NR3C1,NR4A1,AMFR,ZBTB7B,GPLD1,PITX2,PLEKHG6,FYN,PEX5,PVRL2,ACVRL1,SYT7,HAGHL,ALPK3,SPRY4,STARD13,LIFR,TOB1,FOXA1,CAPN1,PKIA |
| 1.098e-02 | -4.51 | GS_dom | interpro domains | IPR003605 | 7 | 4 | 18293 | 2672 |
TGFBR1,ACVR1,ACVR1C,ACVRL1 |
| 1.098e-02 | -4.51 | GoLoco_motif | interpro domains | IPR003109 | 7 | 4 | 18293 | 2672 |
GPSM2,RGS12,RGS14,RAP1GAP |
| 1.098e-02 | -4.51 | Acyl-CoA-binding_protein | interpro domains | IPR000582 | 7 | 4 | 18293 | 2672 |
ACBD5,ECI2,ACBD3,DBI |
| 1.098e-02 | -4.51 | KA1/Ssp2_C | interpro domains | IPR028375 | 7 | 4 | 18293 | 2672 |
PRKAA2,MARK1,MELK,PRKAA1 |
| 1.098e-02 | -4.51 | SUN_dom | interpro domains | IPR012919 | 7 | 4 | 18293 | 2672 |
SUN1,SUN2,SUN3,SUCO |
| 1.098e-02 | -4.51 | Hematopoietin_rcpt_Gp130_CS | interpro domains | IPR003529 | 7 | 4 | 18293 | 2672 |
OSMR,LEPR,LIFR,IL6ST |
| 1.099e-02 | -4.51 | TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS | 81 | 20 | 17758 | 2588 |
UGT8,MGAT4B,PYGL,GALNT7,POMGNT1,B4GALT4,ITGA2B,B4GALNT1,GALNT3,B3GALNT1,FUT2,MGAT4A,A4GALT,FUT8,CSGALNACT1,FUT1,ALG2,STT3B,B4GALT3,GCNT1 |
| 1.100e-02 | -4.51 | Renal function-related traits (sCR)(PMID:22797727) | GWAS genes | Renal function-related traits (sCR)(PMID:22797727) | 7 | 4 | 2389 | 350 |
WDR72,ALDH2,RGS14,SHROOM3 |
| 1.101e-02 | -4.51 | ICK (intestinal cell (MAK-like) kinase) | protein interactions | 22858 | 29 | 10 | 16036 | 2547 |
PSMD1,CDK16,A4GALT,BMP7,TP53,FAM217B,LSM14B,CDK1,VCP,CDK14 |
| 1.101e-02 | -4.51 | HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase) | protein interactions | 3156 | 29 | 10 | 16036 | 2547 |
FAF2,FAM189A2,TMEM30A,AMFR,SPINT2,DCUN1D1,ATP1B3,PRKACA,STARD13,VCP |
| 1.101e-02 | -4.51 | hydrolase activity, acting on ether bonds | molecular function | GO:0016801 | 14 | 6 | 16491 | 2452 |
AHCY,LTA4H,TMEM86B,RNPEP,EPHX4,EPHX1 |
| 1.101e-02 | -4.51 | protein kinase A catalytic subunit binding | molecular function | GO:0034236 | 14 | 6 | 16491 | 2452 |
EZR,PRKAR2B,PJA2,SOX9,PKIA,PRKAR1A |
| 1.101e-02 | -4.51 | thioesterase binding | molecular function | GO:0031996 | 14 | 6 | 16491 | 2452 |
CALM3,CALM2,ARF6,TRAF5,TRAF2,CALM1 |
| 1.102e-02 | -4.51 | chr16p | MSigDB lists | chr16p | 4 | 3 | 17758 | 2588 |
PLK1,NUBP1,CRYM |
| 1.103e-02 | -4.51 | metanephric nephron morphogenesis | biological process | GO:0072273 | 22 | 8 | 16441 | 2455 |
HES1,CTNNB1,LGR4,FMN1,SOX9,SMO,PKD2,SOX8 |
| 1.103e-02 | -4.51 | regulation of osteoblast proliferation | biological process | GO:0033688 | 22 | 8 | 16441 | 2455 |
BMP2,CTHRC1,RHOA,HPSE,CYR61,FGFR2,ITGAV,SOX8 |
| 1.103e-02 | -4.51 | labyrinthine layer morphogenesis | biological process | GO:0060713 | 22 | 8 | 16441 | 2455 |
NCOA3,GRHL2,CYR61,FGFR2,ST14,SPINT2,FZD5,SOCS3 |
| 1.103e-02 | -4.51 | regulation of nuclease activity | biological process | GO:0032069 | 22 | 8 | 16441 | 2455 |
SIRT1,NEIL1,PCNA,AKT1,BAX,TMBIM6,DAB2IP,OAS3 |
| 1.103e-02 | -4.51 | regulation of p38MAPK cascade | biological process | GO:1900744 | 22 | 8 | 16441 | 2455 |
MAP3K3,BMP2,DLG1,EZR,DAB2IP,PHLPP1,RASGRP1,XDH |
| 1.103e-02 | -4.51 | meninges | COSMIC cancer mutations | meninges | 528 | 96 | 17775 | 2585 |
NF2,HSPG2,RET,TP53,ERBB2,BAIAP3,ITPR2,KIF2C,OSR2,TMEM19,HDAC6,CDKN2C,SS18,ZYX,MUC16,ENTPD4,RPS6KA2,CTNNB1,TRANK1,WDR44,TACC2,SMO,POLL,PIK3CA,IRF2,DAB2IP,ARNT2,ANO4,WBP4,TIAM1,MGAT5,CYP1B1,MYO5B,AKT1,ACVR1C,CR2,IDH1,SLC25A5,ULK2,IRS2,PLCH1,PPP2R5A,PTK7,ATP7B,PSMD3,MYLK,TSPAN18,SIPA1L1,EPB41L4A,TANC2,NDST3,DEPDC1,TMTC3,GGA1,FRMD6,SOX9,JAG2,NOTCH2,AIP,CALR,FOXP2,GNS,DOPEY2,RB1,ADD3,PDCD10,MLPH,PTEN,TUBGCP6,PCYOX1,KNTC1,ERBB3,HSPA13,MOXD1,SYTL3,RIMS2,IGDCC4,SYPL1,PIK3R1,FBXO9,COL7A1,ATP8B3,BBS2,GNA11,EGFR,GNAS,MMP15,ARHGAP24,TSC1,PLOD2,FGFR2,NAB2,SLC4A3,ACADM,TMEM14A,EHD1 |
| 1.103e-02 | -4.51 | meningioma | COSMIC cancer mutations | meningioma | 528 | 96 | 17775 | 2585 |
NF2,HSPG2,RET,TP53,ERBB2,BAIAP3,ITPR2,KIF2C,OSR2,TMEM19,HDAC6,CDKN2C,SS18,ZYX,MUC16,ENTPD4,RPS6KA2,CTNNB1,TRANK1,WDR44,TACC2,SMO,POLL,PIK3CA,IRF2,DAB2IP,ARNT2,ANO4,WBP4,TIAM1,MGAT5,CYP1B1,MYO5B,AKT1,ACVR1C,CR2,IDH1,SLC25A5,ULK2,IRS2,PLCH1,PPP2R5A,PTK7,ATP7B,PSMD3,MYLK,TSPAN18,SIPA1L1,EPB41L4A,TANC2,NDST3,DEPDC1,TMTC3,GGA1,FRMD6,SOX9,JAG2,NOTCH2,AIP,CALR,FOXP2,GNS,DOPEY2,RB1,ADD3,PDCD10,MLPH,PTEN,TUBGCP6,PCYOX1,KNTC1,ERBB3,HSPA13,MOXD1,SYTL3,RIMS2,IGDCC4,SYPL1,PIK3R1,FBXO9,COL7A1,ATP8B3,BBS2,GNA11,EGFR,GNAS,MMP15,ARHGAP24,TSC1,PLOD2,FGFR2,NAB2,SLC4A3,ACADM,TMEM14A,EHD1 |
| 1.104e-02 | -4.51 | early endosome membrane | cellular component | GO:0031901 | 107 | 25 | 17570 | 2579 |
SNX8,CLCN3,KREMEN2,ATP9A,HLA-E,HLA-F,EPHA4,FAM21C,EGFR,HLA-A,ZFYVE9,ZFYVE16,MARCH8,HLA-B,SNX13,OCRL,SLC9A6,KIAA0319,APPL2,SNX16,HLA-C,FZD5,WNT3A,PIKFYVE,EHD1 |
| 1.105e-02 | -4.51 | sister chromatid segregation | biological process | GO:0000819 | 100 | 24 | 16441 | 2455 |
PLK1,REC8,PSRC1,ZWINT,DLGAP5,PAPD7,CIT,NDC80,VPS4B,CDCA8,NUSAP1,KIF2C,CCNB1,SPDL1,TOP2A,RB1,KIF14,CDCA5,NEK2,KIF22,CHMP4B,CENPE,ESPL1,SMC4 |
| 1.105e-02 | -4.51 | TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 36 | 11 | 17758 | 2588 |
ACVR1,TGFBR3,FNTA,CDKN1C,ACVRL1,GDF15,TGFBR1,LTBP2,MAP3K7,CITED2,ZFYVE9 |
| 1.109e-02 | -4.50 | branching morphogenesis of an epithelial tube | biological process | GO:0048754 | 143 | 32 | 16441 | 2455 |
ACVR1,NKX3-1,TMTC3,SOX9,CTSZ,GBX2,BMP2,CTNNBIP1,CTNNB1,NPNT,GPC3,BMP7,DLG1,BAX,PPP1CA,ETV4,SLC12A2,SPRY2,DCHS1,TFAP2C,ILK,DAG1,EDNRA,NCOA3,FAT4,FGFR2,AREG,CSF1,PKD2,PLXND1,FOXA1,ADAMTS16 |
| 1.109e-02 | -4.50 | Tyr_kinase_EGF/ERB/XmrK_rcpt | interpro domains | IPR016245 | 4 | 3 | 18293 | 2672 |
ERBB2,ERBB3,EGFR |
| 1.109e-02 | -4.50 | Aldolase_II/adducin_N | interpro domains | IPR001303 | 4 | 3 | 18293 | 2672 |
APIP,ADD3,ADD1 |
| 1.109e-02 | -4.50 | Prot_disulphide_isomerase | interpro domains | IPR005792 | 4 | 3 | 18293 | 2672 |
PDIA3,P4HB,PDIA4 |
| 1.109e-02 | -4.50 | TIMP | interpro domains | IPR001820 | 4 | 3 | 18293 | 2672 |
TIMP3,TIMP2,TIMP1 |
| 1.109e-02 | -4.50 | MAPK_p38 | interpro domains | IPR008352 | 4 | 3 | 18293 | 2672 |
MAPK13,MAPK11,MAPK12 |
| 1.109e-02 | -4.50 | Carboxyl_trans | interpro domains | IPR000022 | 4 | 3 | 18293 | 2672 |
PCCB,ACACB,MCCC2 |
| 1.109e-02 | -4.50 | RetinoicA-induced_16-like | interpro domains | IPR019384 | 4 | 3 | 18293 | 2672 |
FAM160B1,FAM160A1,FAM160A2 |
| 1.109e-02 | -4.50 | TIMP_C | interpro domains | IPR027465 | 4 | 3 | 18293 | 2672 |
TIMP3,TIMP2,TIMP1 |
| 1.109e-02 | -4.50 | AMOP_dom | interpro domains | IPR005533 | 4 | 3 | 18293 | 2672 |
SUSD2,MUC4,ISM1 |
| 1.109e-02 | -4.50 | DUF1736 | interpro domains | IPR013618 | 4 | 3 | 18293 | 2672 |
TMTC1,TMTC2,TMTC3 |
| 1.109e-02 | -4.50 | COA_CT_N | interpro domains | IPR011762 | 4 | 3 | 18293 | 2672 |
PCCB,ACACB,MCCC2 |
| 1.109e-02 | -4.50 | NDRG | interpro domains | IPR004142 | 4 | 3 | 18293 | 2672 |
NDRG2,NDRG3,NDRG1 |
| 1.109e-02 | -4.50 | POLO_box_duplicated_dom | interpro domains | IPR000959 | 4 | 3 | 18293 | 2672 |
PLK1,PLK2,PLK4 |
| 1.109e-02 | -4.50 | COA_CT_C | interpro domains | IPR011763 | 4 | 3 | 18293 | 2672 |
PCCB,ACACB,MCCC2 |
| 1.109e-02 | -4.50 | TIMP_CS | interpro domains | IPR030490 | 4 | 3 | 18293 | 2672 |
TIMP3,TIMP2,TIMP1 |
| 1.111e-02 | -4.50 | Toll Like Receptor 9 (TLR9) Cascade | REACTOME pathways | R-HSA-168138 | 89 | 22 | 8202 | 1235 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,IRF7,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 1.111e-02 | -4.50 | KOBAYASHI_EGFR_SIGNALING_24HR_UP | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_UP | 97 | 23 | 17758 | 2588 |
GRN,CPD,BCAM,TRIM2,ALDH6A1,TSC22D3,FXYD3,SYNE2,FTH1,RAB15,SCNN1A,TJP3,CDK19,METTL7A,BCL6,DRAM1,MAOA,IRF7,LIMCH1,FZD5,CPE,EPHX1,CYP1B1 |
| 1.112e-02 | -4.50 | GSE3982_NEUTROPHIL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_BASOPHIL_DN | 186 | 39 | 17758 | 2588 |
CCNC,ARHGEF3,ACVR1,TUBB4B,PSMD7,OSGIN2,PBX3,GTF3A,PLA2G16,SS18,ADD3,PSMD1,CNTRL,DPYSL2,ARL1,FUT8,TUBG1,RPN2,NFU1,NUP85,FAM134C,SMC4,METAP2,SOD1,MMD,GCLC,PTPN9,RAD17,RHEB,SGPP1,PAFAH1B3,UAP1,HOXA9,PTER,RYK,ZDHHC7,CLIP4,NUP37,CHPT1 |
| 1.112e-02 | -4.50 | GSE11924_TFH_VS_TH17_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH17_CD4_TCELL_UP | 186 | 39 | 17758 | 2588 |
UNKL,GCLM,ALDH6A1,IQGAP1,PNPLA2,FHDC1,WDTC1,SLC1A3,PSIP1,ZFYVE16,CYHR1,TMEM87B,CNTRL,FCHO1,FAM102A,TMEM64,ERBB3,OSBPL7,HP1BP3,FAM69A,GCC2,SSH3,ORAI2,RHOA,FAM160A1,LITAF,CAPNS1,DUSP4,MEST,IFIT3,SPAG1,MPRIP,ABHD12,RNASEL,GRAMD1C,WDR62,ICOSLG,BTBD6,CBX4 |
| 1.112e-02 | -4.50 | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_DN | 186 | 39 | 17758 | 2588 |
CCNI,FAM169A,FAM134A,PSME1,VPS26A,MESDC2,SS18,NAPG,TM9SF2,SNX18,CTSC,FICD,SLC16A6,ARL1,EXOC8,PIK3CA,MDFIC,SLAIN2,TACSTD2,RNF26,CDKN2D,SLC35A1,NEK4,ITCH,OXR1,CCDC34,NPC2,SNX12,NUDT16,SCARB2,FA2H,DDOST,AMMECR1,MATN2,ITPR1,CANT1,ERAP1,NRBP1,DLAT |
| 1.113e-02 | -4.50 | ATGCTGC,MIR-103,MIR-107 | MSigDB lists | ATGCTGC,MIR-103,MIR-107 | 209 | 43 | 17758 | 2588 |
FAF2,FRMD4A,RBM24,RET,KIF23,GABRG2,FAM81A,NFAT5,SIX4,NRP2,CDK14,SIPA1L2,ANK1,TGFBR3,PDCD10,ZNRF2,PACSIN1,WNT3A,TRAM1,FLOT2,SUN2,PHF20L1,PCGF5,TAF5,CELSR2,SNTB2,SEPT6,FOXJ2,PIK3R1,FURIN,CDK5R1,BSDC1,CNTNAP1,HLF,RAB11FIP2,AMMECR1,RAP2C,CAB39,PITPNA,ZC3H12B,HMGA1,PIEZO1,NR2C2 |
| 1.118e-02 | -4.49 | PTW/PP1 phosphatase complex | cellular component | GO:0072357 | 7 | 4 | 17570 | 2579 |
PPP1CB,PPP1CA,PPP1R12A,PPP1R10 |
| 1.121e-02 | -4.49 | ETS | smart domains | SM00413 | 29 | 10 | 9131 | 1455 |
ELK4,ELK3,ETS2,ETV5,ELF5,ELK1,ETV7,ETV4,ETS1,ELF3 |
| 1.121e-02 | -4.49 | regulation of actin cytoskeleton organization | biological process | GO:0032956 | 267 | 54 | 16441 | 2455 |
NF2,SSH1,ADD1,EPS8,SDC4,ARFGEF1,SORBS3,F11R,NCKAP1,SPTB,ICAM1,PICK1,CORO1B,PDGFA,VASP,CTGF,DLG1,CAPG,DIXDC1,TACSTD2,CTTN,NEB,CCDC88A,SSH3,RHOA,BAG4,FMN1,DMTN,DSTN,PIK3R1,PTGER4,RGCC,EZR,PRKCQ,EPHA1,ILK,CDK5R1,RASA1,TSC1,AP1AR,SWAP70,PLEKHH2,ARHGEF19,LIMK1,CTSV,ARAP1,TRIOBP,EFNA5,TMOD2,SPTBN5,ARPC2,ARF6,SHROOM2,F2RL1 |
| 1.123e-02 | -4.49 | protein serine/threonine kinase activator activity | molecular function | GO:0043539 | 18 | 7 | 16491 | 2452 |
CALM3,CAB39,CALM2,SPRY2,IQGAP1,CDK5R1,CALM1 |
| 1.124e-02 | -4.49 | P_typ_ATPase | interpro domains | IPR001757 | 36 | 11 | 18293 | 2672 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP13A3,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 1.124e-02 | -4.49 | ATPase_P-typ_transduc_dom_A | interpro domains | IPR008250 | 36 | 11 | 18293 | 2672 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP13A3,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 1.124e-02 | -4.49 | ATPase_P-typ_P_site | interpro domains | IPR018303 | 36 | 11 | 18293 | 2672 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP13A3,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 1.124e-02 | -4.49 | regulation of RNA polymerase II transcriptional preinitiation complex assembly | biological process | GO:0045898 | 14 | 6 | 16441 | 2455 |
WNT10B,THRA,PSMC1,AHR,PSMC2,GTF2F2 |
| 1.124e-02 | -4.49 | regulation of platelet aggregation | biological process | GO:0090330 | 14 | 6 | 16441 | 2455 |
PRKCQ,SERPINE2,SYK,DMTN,UBASH3B,PRKG1 |
| 1.124e-02 | -4.49 | nitric oxide biosynthetic process | biological process | GO:0006809 | 14 | 6 | 16441 | 2455 |
P2RX4,SLC7A2,NQO1,AKT1,SPR,CYP1B1 |
| 1.124e-02 | -4.49 | regulation of cholesterol biosynthetic process | biological process | GO:0045540 | 14 | 6 | 16441 | 2455 |
SOD1,POR,PEX2,PRKAA1,ABCG1,SEC14L2 |
| 1.125e-02 | -4.49 | Ndc80 complex | cellular component | GO:0031262 | 4 | 3 | 17570 | 2579 |
NUF2,SPC25,NDC80 |
| 1.125e-02 | -4.49 | MHC class I peptide loading complex | cellular component | GO:0042824 | 4 | 3 | 17570 | 2579 |
CALR,TAPBP,TAP1 |
| 1.129e-02 | -4.48 | GNG12 (guanine nucleotide binding protein (G protein), gamma 12) | protein interactions | 55970 | 17 | 7 | 16036 | 2547 |
PKM,SLC12A2,FLOT2,GNB2,CAPN1,FLOT1,FHL2 |
| 1.129e-02 | -4.48 | ADRA1D (adrenoceptor alpha 1D) | protein interactions | 146 | 17 | 7 | 16036 | 2547 |
ACTA2,SNTA1,SNTB1,AMFR,SNTB2,CKAP4,UTRN |
| 1.129e-02 | -4.48 | CDCA3 (cell division cycle associated 3) | protein interactions | 83461 | 17 | 7 | 16036 | 2547 |
CUL1,WEE1,ATP6V1C1,TRAF2,CTDSP2,CTDSPL,CTDSP1 |
| 1.129e-02 | -4.48 | VRK1 (vaccinia related kinase 1) | protein interactions | 7443 | 17 | 7 | 16036 | 2547 |
SERPINB5,TFAP4,RACGAP1,CYP1A1,EGFR,PYM1,TP53 |
| 1.130e-02 | -4.48 | schwannoma | COSMIC cancer mutations | schwannoma | 27 | 9 | 17775 | 2585 |
NF2,CTNNB1,AKT1,PTEN,RET,PIK3CA,IDH1,GNA11,EGFR |
| 1.135e-02 | -4.48 | LINDVALL_IMMORTALIZED_BY_TERT_DN | MSigDB lists | LINDVALL_IMMORTALIZED_BY_TERT_DN | 76 | 19 | 17758 | 2588 |
MZT1,ENO2,HSPG2,CRIP2,SAT1,ARL4C,LMCD1,LHFPL2,ANTXR1,LGALS3BP,MAP1B,PLOD2,CYR61,PTK7,LTBP2,PER3,ARL4D,PTGES,MDFI |
| 1.135e-02 | -4.48 | MODULE_297 | MSigDB lists | MODULE_297 | 76 | 19 | 17758 | 2588 |
KLK10,KLK5,LMTK3,KLHL13,FXYD3,ITGA6,COL7A1,PPP1R14C,S100A2,EFNB1,CYP26A1,PTGS2,CA2,AREG,ALDH1A3,SERPINB5,MAOA,CDH3,F2RL1 |
| 1.135e-02 | -4.48 | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | MSigDB lists | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | 76 | 19 | 17758 | 2588 |
DLGAP1,SLC25A13,CASP9,TGFBR1,TAF6L,EGR3,PHF1,IER3,M6PR,IL1R1,ATP1A1,ETS2,ZFP36,SRP54,HMGA1,ATP6V1C1,LGMN,PTPRE,AHR |
| 1.135e-02 | -4.48 | MULLIGHAN_NPM1_SIGNATURE_3_UP | MSigDB lists | MULLIGHAN_NPM1_SIGNATURE_3_UP | 321 | 62 | 17758 | 2588 |
PLA2G4A,UNKL,ARHGAP11A,PINK1,LGR4,IL15,ARHGEF11,CENPI,DNAJB2,RASSF7,CTDSPL,C5orf30,PBX3,COL4A5,B4GALT4,SEPP1,ARHGEF40,HOXB2,SSX2IP,TNS3,FRY,METTL7A,IQCE,KCNS3,BAX,GOT1,KIF22,WWP1,OSTF1,MAP3K7,SGCB,SNX10,DGKG,NCOA2,SMC4,CTH,METAP2,WBP5,HMGN5,PIP4K2C,ACO1,ERP44,RAB38,EPHA1,RHEB,VCP,CDK5R1,SOX13,PIAS3,MAN2A2,NCOA3,TBC1D17,IDE,NGFRAP1,DCK,HOXA9,NEIL3,AGBL5,SH3GLB2,MAP3K5,TMEM14A,DOCK9 |
| 1.138e-02 | -4.48 | GSE17721_LPS_VS_PAM3CSK4_16H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_16H_BMDM_UP | 192 | 40 | 17758 | 2588 |
CASP3,SPRED1,CDS2,AGRN,IL15RA,LGALS3,DHPS,PTTG1,IL18,F11R,CD274,TMCC3,ICAM5,CST3,SORL1,CD70,HLA-C,PIM1,SGCB,SNX10,TIAM1,LAMP2,PTPN18,ELK3,RIPK2,FNDC3A,GNA11,POR,ARF4,SCARB2,FYN,ITPR1,ETAA1,HMGA1,GEM,RBM43,PLOD3,ARPC2,RGS14,PHC1 |
| 1.138e-02 | -4.48 | GSE17721_PAM3CSK4_VS_CPG_12H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_12H_BMDM_DN | 192 | 40 | 17758 | 2588 |
AGRN,FAM169A,IL15RA,LGALS3,PARP14,SERPINB9,CD274,CHAC2,LGALS3BP,EFR3A,FRYL,ELF5,FUT8,CST3,TFAP2A,RAB20,CD70,ECE1,PIM1,MAPK7,TSPAN1,MYLIP,TIPARP,C9orf72,MX1,MOB4,B3GNT2,NUB1,ARFRP1,ALCAM,PTGS2,RND3,NR1D2,MAP2,WFS1,NFKBIA,KLK7,NFKBIZ,CHMP4B,IRF1 |
| 1.138e-02 | -4.48 | GSE17721_CTRL_VS_LPS_6H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_6H_BMDM_DN | 192 | 40 | 17758 | 2588 |
ACVR1,TTC39B,DHPS,RUSC2,CYP2J2,RASA2,ETNK1,IL18,F11R,KREMEN1,SPTB,CMTM6,REPS1,IER3,ARTN,TIMP1,LLGL2,RANBP1,CST3,H2AFY,SNX16,TSPAN33,PPIF,GCA,SLC5A11,PLSCR1,SLC39A8,MPP1,NUB1,FURIN,TANC1,PSMA4,ARF4,MAGED2,PTPRJ,ACADSB,RND3,WFS1,PTGES,AHR |
| 1.138e-02 | -4.48 | GSE27786_NKCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_NKCELL_VS_NEUTROPHIL_UP | 192 | 40 | 17758 | 2588 |
TCF25,NFKBIE,PSME2,MAN1A2,C6orf106,POMGNT1,OAT,PDGFB,EXT2,TMCC3,ZDHHC21,SAP130,SESN3,PFKL,IL6ST,GTF2F2,SLC44A2,RNASEH2A,ARL4D,SPRY2,DDX59,PARP9,HES1,HPS3,PLEKHA6,TMEM68,CITED4,GUSB,SH3BGRL,SAT1,PIK3R1,PRKCQ,GABARAPL1,NAAA,RCBTB2,NAB2,PDXK,TTC39C,JAK3,DIS3L |
| 1.138e-02 | -4.48 | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP | 192 | 40 | 17758 | 2588 |
SUN1,ACVR1,ST13,FAM169A,ENO2,IBTK,GATA3,NUCB2,SLC25A36,CAPN2,DAZAP1,ALG13,FBXO7,FAM20B,FBXL14,BRD7,MDFIC,KLF9,TIAM1,MPHOSPH9,TRAK2,UPF3A,NAGPA,SUN2,TGIF1,SEPT6,PIK3R1,CLSTN1,MCFD2,TXK,TSC1,LRIG1,IARS2,SPAG7,INPP4B,MDH1,PIEZO1,ATP1B3,TBC1D4,DOCK9 |
| 1.138e-02 | -4.48 | GSE17721_CTRL_VS_POLYIC_24H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_24H_BMDM_DN | 192 | 40 | 17758 | 2588 |
UGP2,CD82,GDF15,JAG2,RBP7,KTN1,KIAA1161,RAD23A,CDH1,TIMP1,BHLHE41,LMO4,IL6ST,RANBP1,CST3,PSMC2,MDFIC,TSPAN13,TSPAN33,RIPK2,LAP3,GCLC,NUB1,CCBL2,ARFRP1,PDK3,SPTLC2,PSMA4,ABR,ARF4,CD83,RBM47,GDE1,MMP17,NFKBIA,SPAG7,TTC39C,PLIN3,PTGES,TMEM131 |
| 1.138e-02 | -4.48 | GSE20366_TREG_VS_TCONV_UP | MSigDB lists | GSE20366_TREG_VS_TCONV_UP | 192 | 40 | 17758 | 2588 |
PRKAA2,CASP3,NCKAP5,DYRK3,ENO2,AK7,GATA3,IL18,EGR3,PATL2,NUCB2,DHRS3,ZFYVE9,IL17RB,ADPRHL1,PPME1,PAPL,DAB2IP,EGLN3,FAR2,LMAN1,SOCS5,P2RX4,ENPP4,AMOTL2,SHMT1,ERMP1,PFKFB2,PRICKLE1,ZSCAN12,SLC17A5,TCEAL8,NEIL1,MATN2,MDH1,ZBTB34,ITGAV,NDFIP1,LRRC57,FAM134B |
| 1.138e-02 | -4.48 | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP | 192 | 40 | 17758 | 2588 |
KLK10,RUNX2,IGFBP6,GPR107,LGALS3,PPM1J,HEBP1,SDC4,FLOT1,MAPK4,FAM198B,SLC25A35,KIAA1147,GBX2,SPP1,ANK1,ARTN,RABEP2,DRAM1,ECE1,C12orf75,TIPARP,S100A6,GCNT1,SUSD3,MYO5B,EPB41L5,RUNX3,LOXL2,DOCK5,BSDC1,STX3,SEC14L2,FRMD4B,FOXD2,NUCB1,CSF1,SYT13,DEF6,ANXA11 |
| 1.138e-02 | -4.48 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | 192 | 40 | 17758 | 2588 |
HECA,ITGA6,CUL4B,ERCC6L,ASAH1,TESK2,PHLDA1,DUSP5,FAM111A,FAM46A,SLC35B4,TSPAN13,PACSIN1,C12orf75,METAP2,SOCS5,FADS2,USP31,DENND1B,PIK3R1,MBNL3,PTGER4,DUSP4,CD83,CMTM7,ATP1A1,ANKRD6,PTER,ITPR1,ABCB1,FAM83D,PGM2L1,MAOA,STK39,PLXND1,RELL1,NCAPG2,TBC1D4,CBX4,DLAT |
| 1.138e-02 | -4.48 | GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDM_DN | 192 | 40 | 17758 | 2588 |
CCDC109B,HSP90B1,DHPS,SWI5,MRAS,TEX2,CHAC2,APPBP2,B3GALNT1,RNF128,SNX18,ARL1,DDHD2,SLC30A6,FCHO1,PRKCI,PIK3CA,SLAIN2,TRAM1,IL1RAP,CRTAP,WBP5,MOB4,ADAM17,SEC61B,CALCRL,PIM3,PRRC1,BLVRA,LDB2,CDK1,ZMPSTE24,RND3,OTUD6B,NAB2,ALPK3,PPP2R3C,UBE2C,PTGES,MAFF |
| 1.138e-02 | -4.48 | GSE27786_BCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_BCELL_VS_NKTCELL_UP | 192 | 40 | 17758 | 2588 |
NFKBIE,ERCC6L,GMCL1,DNPEP,SETDB2,PIK3AP1,STEAP2,BRI3,MAPK11,RNASEH2A,ETHE1,MYO5A,MSH6,FAM69A,SYPL1,TGIF1,VPS11,RHOA,B3GNT2,CXXC5,MPP1,LPGAT1,HSPA12A,SHARPIN,TRIM35,CCNF,ITPR3,RNF19B,RAB2B,PLEKHB1,CMTM7,PRDX4,CNOT2,CARHSP1,SLC2A6,NR4A3,DCUN1D1,CSGALNACT1,ICOSLG,ST3GAL1 |
| 1.139e-02 | -4.48 | ETS_DOMAIN_2 | prosite domains | PS00346 | 26 | 9 | 11866 | 1802 |
ELK4,ELK3,ETS2,ETV5,ELF5,ELK1,ETV4,ETS1,ETV7 |
| 1.139e-02 | -4.47 | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | 108 | 25 | 17758 | 2588 |
ZNF462,ZMAT1,TM2D2,FAM92A1,FOXM1,CAST,CORO2A,TMX4,PIK3R1,PBX3,PYGL,PRKCQ,ERP44,TGFBR1,TMEM19,BEX2,STX3,IGF1R,MITF,ZDHHC13,SERPINB5,DAB2IP,PLD1,MAP3K7,TBC1D4 |
| 1.139e-02 | -4.47 | GCTTGAA,MIR-498 | MSigDB lists | GCTTGAA,MIR-498 | 108 | 25 | 17758 | 2588 |
SPRED1,PACSIN2,RUNX2,RBM24,TSC22D3,RNF11,PIK3R1,ARL4C,MORF4L2,RAB6A,DUSP4,BAHD1,SIX4,SOCS3,CTNS,KLF12,C1orf21,UBE2J1,AGBL5,IRF2,EPB41L4B,PDIA6,CBX4,CAMK2G,ATP2B1 |
| 1.141e-02 | -4.47 | FRIZZLED | prints domains | PR00489 | 11 | 5 | 4759 | 661 |
FZD5,FZD4,FZD7,FZD6,SMO |
| 1.141e-02 | -4.47 | PAPAIN | prints domains | PR00705 | 11 | 5 | 4759 | 661 |
CTSL,CTSZ,CTSC,CTSB,CTSV |
| 1.141e-02 | -4.47 | human chr3q21-q22 | chromosome location | human chr3q21-q22 | 2 | 2 | 26250 | 2805 |
AMOTL2,PCCB |
| 1.141e-02 | -4.47 | human chr2q22 | chromosome location | human chr2q22 | 2 | 2 | 26250 | 2805 |
NEB,ARHGEF4 |
| 1.141e-02 | -4.47 | human chrXq21.33-q22.3 | chromosome location | human chrXq21.33-q22.3 | 2 | 2 | 26250 | 2805 |
ARMCX6,TMSB15A |
| 1.145e-02 | -4.47 | GROSS_ELK3_TARGETS_UP | MSigDB lists | GROSS_ELK3_TARGETS_UP | 27 | 9 | 17758 | 2588 |
CPD,CCND1,TIMP2,CYR61,ARRB1,F2R,CPE,MYLIP,ABCG1 |
| 1.145e-02 | -4.47 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | MSigDB lists | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | 27 | 9 | 17758 | 2588 |
CALM2,RASGRF1,RPS6KA2,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D,RPS6KA3 |
| 1.146e-02 | -4.47 | ciliary basal body | cellular component | GO:0036064 | 86 | 21 | 17570 | 2579 |
TTC8,PIFO,LCA5,AKT1,B9D2,POC1B,FOPNL,CCSAP,EZR,RAB3IP,BBS2,SSX2IP,DZIP1L,TRAF3IP1,TUBG1,SSNA1,PKD2,RP2,CFAP20,CEP41,RPGR |
| 1.147e-02 | -4.47 | negative regulation of fat cell differentiation | biological process | GO:0045599 | 40 | 12 | 16441 | 2455 |
SIRT1,ENPP1,SORT1,WNT10B,GATA2,ASXL1,WWTR1,E2F1,GATA3,GPER1,TRIB2,WNT3A |
| 1.147e-02 | -4.47 | regulation of substrate adhesion-dependent cell spreading | biological process | GO:1900024 | 40 | 12 | 16441 | 2455 |
CALR,AP1AR,MFI2,DMTN,ARHGEF7,CORO1C,TRIOBP,DNM2,TACSTD2,ARPC2,FAM21C,FBLN1 |
| 1.147e-02 | -4.47 | hair cell differentiation | biological process | GO:0035315 | 40 | 12 | 16441 | 2455 |
PITX2,HES1,SOD1,USH1C,CTNNB1,MCOLN3,SCRIB,JAG2,ERCC2,GFI1,TMC1,PLS3 |
| 1.147e-02 | -4.47 | V$TAXCREB_01 | MSigDB lists | V$TAXCREB_01 | 130 | 29 | 17758 | 2588 |
PHF20L1,ARMCX3,TRAPPC10,PTPRU,ASXL1,DNAJB2,IRX4,KDELR3,BAHD1,SLC25A5,FOS,TSPAN7,XPR1,APPBP2,IRF2BPL,LMO4,FOSB,NR4A3,PLK4,OTUB2,CDKN1B,RFX5,TAGLN2,KLF9,GEM,OSR1,MAFF,DLAT,DUSP1 |
| 1.149e-02 | -4.47 | regulation of receptor recycling | biological process | GO:0001919 | 18 | 7 | 16441 | 2455 |
SCRIB,AP1AR,ECE1,BVES,OPTN,ARAP1,VAMP3 |
| 1.149e-02 | -4.47 | protein hydroxylation | biological process | GO:0018126 | 18 | 7 | 16441 | 2455 |
EGLN3,P4HB,P4HA2,P3H2,P4HA3,CRTAP,EGLN1 |
| 1.150e-02 | -4.47 | ovary-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | ovary-carcinoma-undifferentiated_carcinoma | 41 | 12 | 17775 | 2585 |
GNAS,RB1,CTNNB1,CDH1,PTEN,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR,MSH6 |
| 1.151e-02 | -4.46 | CTTNBP2 (cortactin binding protein 2) | protein interactions | 83992 | 25 | 9 | 16036 | 2547 |
MOB4,PDCD10,STK26,STRIP2,RAPGEF2,STRN4,CTTN,ZRANB1,RAD21 |
| 1.151e-02 | -4.46 | BACE1 (beta-site APP-cleaving enzyme 1) | protein interactions | 23621 | 25 | 9 | 16036 | 2547 |
PLSCR1,GGA1,FBXO2,FURIN,PDIA3,BRI3,ATP1B1,ITM2C,RANBP9 |
| 1.151e-02 | -4.46 | FLT1 (fms-related tyrosine kinase 1) | protein interactions | 2321 | 25 | 9 | 16036 | 2547 |
PGF,PLCG1,FYN,CTNNB1,PLCG2,PIK3R1,YES1,CBL,NRP2 |
| 1.151e-02 | -4.46 | FRS3 (fibroblast growth factor receptor substrate 3) | protein interactions | 10817 | 25 | 9 | 16036 | 2547 |
PLSCR1,PRKCI,ERBB2,AES,CBL,ADAMTSL4,SPRY2,SH3KBP1,RND1 |
| 1.151e-02 | -4.46 | TTC27 (tetratricopeptide repeat domain 27) | protein interactions | 55622 | 25 | 9 | 16036 | 2547 |
GFPT1,UFD1L,ACVR1,HDAC11,CSTF2,TGFBR1,FBXO6,PPP2R5D,EGFR |
| 1.152e-02 | -4.46 | alcohol metabolic process | biological process | GO:0006066 | 343 | 67 | 16441 | 2455 |
PLA2G4A,INPP5D,PHOSPHO1,PLA2G16,LPIN3,CYP39A1,EPM2A,CDS1,CALM2,INPP5E,APLP2,CYP1A1,IMPAD1,ALDH1A3,PLCG2,RDH14,SLC44A1,AKR1B1,GOT1,MINPP1,LGMN,CYP1B1,SOAT1,CYB5R2,SLC44A3,SGPP1,PLCH1,PLCG1,ALDH3B1,INPP4B,PNPLA6,SLC27A1,ITPKA,CHPT1,ABCA1,PRKAA2,GALK1,INPPL1,PRKAA1,CALM3,ISYNA1,DHRS3,LBR,PTEN,OCRL,FDXR,SORL1,SLC44A2,ALDH7A1,PLCB2,ALDH3A2,ALDH2,CALM1,NPC2,PCTP,SPTLC2,LEPR,GPLD1,FECH,PRKAG2,LDLRAP1,PLA2G15,DBI,DGAT2,SAMD8,APOL2,ABCG1 |
| 1.153e-02 | -4.46 | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP | 175 | 37 | 17758 | 2588 |
CCNC,UNC93B1,PPP1R2,ZNF395,POC1B,PKP2,TGOLN2,TEX2,GRK6,FLT3,ZYX,OXCT1,CTSC,ELF5,KLF3,FAM63A,PHKA2,RASGEF1A,SULF2,HPS3,CXXC5,PSRC1,LONRF3,MPP1,SH3BGRL,BNIP3L,SPATA13,C2orf69,SLC25A5,LEPR,TCN2,SCARB2,RCBTB2,NR1D2,CLIP4,REEP4,AIFM3 |
| 1.153e-02 | -4.46 | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP | 175 | 37 | 17758 | 2588 |
IER5L,KIF3C,LZTFL1,FARP1,REPS2,ZNF395,NDRG1,TESK2,MERTK,TMCC3,CD109,CPNE2,RPS6KA2,IGF1R,LRRC6,ITGB8,WWP1,ZNF230,TSPAN13,CERS2,HP1BP3,MBP,TNS1,PTGFRN,POR,ULK2,USP6,TMEM50B,SLC6A6,ZNF641,SWAP70,NGFRAP1,CELF5,PPM1H,GEM,POMT1,C1orf43 |
| 1.153e-02 | -4.46 | GCNP_SHH_UP_LATE.V1_UP | MSigDB lists | GCNP_SHH_UP_LATE.V1_UP | 175 | 37 | 17758 | 2588 |
DLGAP5,FRMD6,SERPINB9,KIF2C,LBR,SIX4,TEAD3,SSX2IP,TOP2A,ZFX,LLGL2,PRC1,PIK3CA,MAP3K7,CASD1,SMC4,CKS2,UFD1L,VPS4B,PLEKHA7,NUSAP1,LOXL2,AURKB,CDC25C,CASP4,CDK1,GALNT3,DNM1L,TIMM8A,PVRL2,PLK2,RYK,AURKA,CLIP4,SGOL1,E2F8,FOXA1 |
| 1.153e-02 | -4.46 | GSE10325_BCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_BCELL_VS_MYELOID_UP | 175 | 37 | 17758 | 2588 |
ADD1,AES,RASGRP3,GTF3A,TRIB2,CCDC92,OXCT1,GNB5,CD22,AKR1B1,TSPAN13,ITM2C,RASGRP1,SMAGP,FAM69A,KIAA0040,SEPT6,SYBU,SYNE2,CR2,EZR,ESYT1,EAF2,ITPR3,OPTN,STK17A,PRIM1,BANK1,FAM3C,CSGALNACT1,FAM117A,TLE1,PIK3C2B,MAPK13,TRAF5,CBX5,CD81 |
| 1.154e-02 | -4.46 | N-glycan antennae elongation in the medial/trans-Golgi | REACTOME pathways | R-HSA-975576 | 22 | 8 | 8202 | 1235 |
MAN2A2,FUCA1,MGAT4A,FUT8,MGAT4B,B4GALT4,B4GALT3,MGAT5 |
| 1.154e-02 | -4.46 | Metabolism of nitric oxide | REACTOME pathways | R-HSA-202131 | 22 | 8 | 8202 | 1235 |
CALM2,DDAH1,AKT1,CALM1,DNM2,CALM3,SPR,ZDHHC21 |
| 1.154e-02 | -4.46 | eNOS activation and regulation | REACTOME pathways | R-HSA-203765 | 22 | 8 | 8202 | 1235 |
CALM2,DDAH1,AKT1,CALM1,DNM2,CALM3,SPR,ZDHHC21 |
| 1.154e-02 | -4.46 | Regulation of RhoA activity | Pathway Interaction DB | rhoa_reg_pathway | 46 | 17 | 2227 | 480 |
RHOA,ARHGEF28,FARP1,ARHGEF3,ARAP3,ARHGEF11,ARHGDIB,ABR,ARHGAP35,ARHGEF10L,PLEKHG6,MCF2L,ARAP1,CDKN1B,ARHGAP4,DEF6,NGEF |
| 1.159e-02 | -4.46 | formation of primary germ layer | biological process | GO:0001704 | 111 | 26 | 16441 | 2455 |
EPB41L5,ACVR1,TNRC6C,NF2,COL7A1,DUSP4,PRKACA,EXT2,DUSP5,COL12A1,MMP15,ITGA3,ETS2,CTNNB1,TWSG1,FGFR2,HTT,ITGA7,BMP7,ELF5,COL6A1,NR4A3,ITGAV,WNT3A,DUSP1,PRKAR1A |
| 1.159e-02 | -4.46 | regulation of cell cycle arrest | biological process | GO:0071156 | 111 | 26 | 16441 | 2455 |
BIN1,HMGN5,PSMB4,FOXM1,CAST,PSME2,PSMD7,TP53,RGCC,PSMD10,PSME1,PRKACA,PSMA4,CDK5R1,TP73,TFAP4,CCND1,PSMD1,PSMD3,PSMC2,CDKN1B,DAB2IP,PKD2,GPER1,PSMC1,PSMA5 |
| 1.162e-02 | -4.46 | Mit_carrier | interpro domains | IPR002067 | 27 | 9 | 18293 | 2672 |
SLC25A48,SLC25A45,SLC25A24,SLC25A4,SLC25A13,SLC25A40,SLC25A43,SLC25A5,SLC25A36 |
| 1.163e-02 | -4.45 | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 198 | 41 | 17758 | 2588 |
FAF2,IBTK,MRPS15,TBC1D1,MAN1A2,ETNK1,CALM3,PDXDC1,GNS,CALM2,RCN1,SS18,CTSC,IL6ST,BHLHE41,RRBP1,FUT8,SGK1,ACSL4,APOBEC3G,MSH6,NEK4,GFPT1,PCCB,MLEC,TIMP2,LAP3,MICB,DSTN,ACBD3,CALM1,FNDC3A,PDHX,VCP,SLC25A4,DNM1L,PRCP,WFS1,NDFIP1,NRBP1,ISOC1 |
| 1.164e-02 | -4.45 | - | gene3d domains | 1.10.555.10 | 66 | 18 | 9988 | 1574 |
ARHGAP11A,ARAP3,ARAP2,DEPDC1,RALBP1,PIK3R1,RACGAP1,ABR,SYDE2,ARHGAP35,ARHGAP24,ARHGAP42,SH3BP1,OCRL,FAM13B,ARAP1,ARHGAP4,STARD13 |
| 1.166e-02 | -4.45 | cellular lipid catabolic process | biological process | GO:0044242 | 160 | 35 | 16441 | 2455 |
PLA2G4A,CPT2,PNPLA2,HEXB,PLD2,LPIN3,PRKACA,ECI1,CYP26A1,SGPL1,FABP6,PLCG2,ECI2,ABCD1,PPP1CA,ACOX2,ACAD8,NAGA,GM2A,CYP1B1,CYP26B1,PCCB,CYP4F3,PLCG1,ACADSB,FAAH,ACAD10,ABHD12,PEX2,PLA2G15,PPP1CB,ACADM,GLA,PLD1,ACOT7 |
| 1.167e-02 | -4.45 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | 71 | 18 | 17758 | 2588 |
CPD,TEF,PNPLA2,EPS8,MAP1LC3B,SESN1,CASP4,GABARAPL1,PROM1,NR1D2,AOX1,GEM,TMEM159,NCAM1,LIFR,ABCA1,NGEF,EPHX1 |
| 1.167e-02 | -4.45 | KEGG_MELANOMA | MSigDB lists | KEGG_MELANOMA | 71 | 18 | 17758 | 2588 |
PDGFC,AKT1,PIK3R1,TP53,PDGFB,FGF19,EGFR,PDGFA,CCND1,RB1,CDH1,IGF1R,PTEN,MITF,FGF18,E2F1,PIK3CA,PIK3CD |
| 1.167e-02 | -4.45 | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | MSigDB lists | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | 71 | 18 | 17758 | 2588 |
LMO7,RAB3B,LGR4,CTNNAL1,PLAUR,C3orf52,LOXL2,EPHA1,S100A2,STEAP1,EGFR,PARM1,PLOD2,COL13A1,WWTR1,TSPAN1,F2RL1,PTGES |
| 1.167e-02 | -4.45 | transforming growth factor beta receptor activity, type I | molecular function | GO:0005025 | 4 | 3 | 16491 | 2452 |
TGFBR1,ACVR1,ACVRL1 |
| 1.167e-02 | -4.45 | ErbB-2 class receptor binding | molecular function | GO:0005176 | 4 | 3 | 16491 | 2452 |
NRG1,ERBB2IP,MUC4 |
| 1.167e-02 | -4.45 | oxoglutarate dehydrogenase (succinyl-transferring) activity | molecular function | GO:0004591 | 4 | 3 | 16491 | 2452 |
DHTKD1,MRPS36,OGDHL |
| 1.167e-02 | -4.45 | aryl hydrocarbon receptor binding | molecular function | GO:0017162 | 4 | 3 | 16491 | 2452 |
ARNT2,AIP,ARNT |
| 1.167e-02 | -4.45 | activin receptor activity, type I | molecular function | GO:0016361 | 4 | 3 | 16491 | 2452 |
ACVR1,ACVRL1,ACVR1C |
| 1.167e-02 | -4.45 | beta-adrenergic receptor kinase activity | molecular function | GO:0047696 | 4 | 3 | 16491 | 2452 |
GRK6,ADRBK1,ADRBK2 |
| 1.167e-02 | -4.45 | AP-1 adaptor complex binding | molecular function | GO:0035650 | 4 | 3 | 16491 | 2452 |
AP1AR,RAB38,ARPC2 |
| 1.167e-02 | -4.45 | TAP1 binding | molecular function | GO:0046978 | 4 | 3 | 16491 | 2452 |
TAPBP,HLA-F,TAP1 |
| 1.167e-02 | -4.45 | ErbB-3 class receptor binding | molecular function | GO:0043125 | 4 | 3 | 16491 | 2452 |
ERBB2,NRG1,PIK3R1 |
| 1.167e-02 | -4.45 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity | molecular function | GO:0047238 | 4 | 3 | 16491 | 2452 |
CHSY3,CHPF,CSGALNACT1 |
| 1.167e-02 | -4.45 | procollagen-proline 4-dioxygenase activity | molecular function | GO:0004656 | 4 | 3 | 16491 | 2452 |
P4HB,P4HA2,P4HA3 |
| 1.168e-02 | -4.45 | TBC1D22A (TBC1 domain family, member 22A) | protein interactions | 25771 | 21 | 8 | 16036 | 2547 |
PVRL2,ACBD3,FLYWCH2,FDXR,EPHA4,ARFGEF1,ACSL4,QSOX2 |
| 1.168e-02 | -4.45 | ANK1 (ankyrin 1, erythrocytic) | protein interactions | 286 | 21 | 8 | 16036 | 2547 |
SLC4A3,NBPF3,TGFBR1,ITPR3,TIAM1,HSPB1,SPTB,L1CAM |
| 1.168e-02 | -4.45 | SLC12A2 (solute carrier family 12 (sodium/potassium/chloride transporter), member 2) | protein interactions | 6558 | 21 | 8 | 16036 | 2547 |
LGALS3,FAM189A2,LGALS8,MCOLN3,STK39,ILK,SLC12A2,EGFR |
| 1.168e-02 | -4.45 | DEGS1 (delta(4)-desaturase, sphingolipid 1) | protein interactions | 8560 | 21 | 8 | 16036 | 2547 |
NAGPA,CYHR1,UFD1L,NRG1,HDGFRP2,SCARA3,FLOT2,EGFR |
| 1.168e-02 | -4.45 | NUF2 (NUF2, NDC80 kinetochore complex component) | protein interactions | 83540 | 21 | 8 | 16036 | 2547 |
ZWINT,SPC25,NDC80,AURKA,BUB1,CENPE,AURKB,DGKE |
| 1.168e-02 | -4.45 | IL1RAP (interleukin 1 receptor accessory protein) | protein interactions | 3556 | 21 | 8 | 16036 | 2547 |
CCNI,IL1R1,MARCH8,IRAK1,PIK3R1,PRKCI,IL18R1,SIRPA |
| 1.168e-02 | -4.45 | TPP2 (tripeptidyl peptidase II) | protein interactions | 7174 | 21 | 8 | 16036 | 2547 |
TRIM47,CYP1A1,PPP1R12A,PLOD2,PPP1R16A,MSH2,DENND2D,TIPRL |
| 1.168e-02 | -4.45 | protein localization to plasma membrane | biological process | GO:0072659 | 149 | 33 | 16441 | 2455 |
TSPAN15,FLOT1,PKP2,MPP5,F11R,EMP2,TSPAN17,RAB15,ANK1,CDH1,DLG1,ZDHHC23,PLEKHF1,PACSIN1,FLOT2,TMED2,MYO5A,TSPAN33,GCC2,BAG4,RAB3B,KCNIP3,CRB3,RAPGEF2,VAMP3,EZR,KIF13A,ARFRP1,ATP1B1,BBS2,OPTN,RAB31,ATP1B3 |
| 1.169e-02 | -4.45 | REGULATION_OF_MITOSIS | MSigDB lists | REGULATION_OF_MITOSIS | 41 | 12 | 17758 | 2588 |
NPM2,ZWINT,CCNA2,NEK2,BUB1,NUSAP1,KNTC1,RAD17,PKMYT1,ANLN,UBE2C,CDC25C |
| 1.170e-02 | -4.45 | late endosome | cellular component | GO:0005770 | 191 | 40 | 17570 | 2579 |
LAMP1,MTM1,ANKRD13D,CD63,TMEM55B,BACE1,MVB12B,PARM1,SDF4,M6PR,RNF128,EXOC8,SNX16,PIKFYVE,RAB27B,LGMN,F2R,TTPA,TMEM9,MYO5A,LAMP2,CLCN3,VPS11,MMD,IFITM3,RAPGEF2,VPS4B,AP5M1,SLC11A2,RHOB,AP1AR,CTNS,HTT,ATP7B,SLC9A6,DYSF,CHMP4B,PLD1,SLC31A2,STARD3NL |
| 1.171e-02 | -4.45 | galactosidase activity | molecular function | GO:0015925 | 7 | 4 | 16491 | 2452 |
GLB1,GLB1L2,GLA,NAGA |
| 1.171e-02 | -4.45 | ligase activity, forming carbon-carbon bonds | molecular function | GO:0016885 | 7 | 4 | 16491 | 2452 |
PCCB,ACACB,MCCC2,MCCC1 |
| 1.171e-02 | -4.45 | interleukin-17 receptor activity | molecular function | GO:0030368 | 7 | 4 | 16491 | 2452 |
IL17RB,IL17RA,IL27RA,IL6ST |
| 1.171e-02 | -4.45 | aldehyde dehydrogenase [NAD(P)+] activity | molecular function | GO:0004030 | 7 | 4 | 16491 | 2452 |
ALDH3B1,ALDH2,ALDH3A2,ALDH1A3 |
| 1.171e-02 | -4.45 | procollagen-proline dioxygenase activity | molecular function | GO:0019798 | 7 | 4 | 16491 | 2452 |
P4HB,P3H2,P4HA2,P4HA3 |
| 1.174e-02 | -4.44 | chromosome, centromeric region | cellular component | GO:0000775 | 174 | 37 | 17570 | 2579 |
SPC25,HJURP,PPP1R12A,CENPI,CDCA8,NDC80,ERCC6L,NUF2,KIF2C,CCNB1,SPDL1,CENPN,KMT5C,NEK2,H2AFY,KIF22,BUB1,KNTC1,NUP85,PLK1,REC8,CENPA,ZWINT,CENPC,SEPT6,AURKB,SKA1,DCTN6,PPP2R5A,CDCA5,AURKA,CENPE,NUP37,NDE1,SGOL1,CBX5,RAD21 |
| 1.175e-02 | -4.44 | vacuolar transport | biological process | GO:0007034 | 90 | 22 | 16441 | 2455 |
NAGPA,LAMP1,GCC2,MTM1,VPS11,SORT1,TRAPPC8,KIF13A,RHOB,HMGXB4,M6PR,ZFYVE16,SCARB2,FAM160A2,GNPTAB,SNX16,SORL1,CHMP4B,SPTBN5,ARSB,NDFIP1,HOOK1 |
| 1.176e-02 | -4.44 | human chr4q22.1 | chromosome location | human chr4q22.1 | 19 | 6 | 26250 | 2805 |
ARHGAP24,HERC5,PKD2,SPP1,CCSER1,HERC6 |
| 1.182e-02 | -4.44 | negative regulation of Rac protein signal transduction | biological process | GO:0035021 | 4 | 3 | 16441 | 2455 |
STMN3,ARHGAP24,ARAP3 |
| 1.182e-02 | -4.44 | negative regulation of purine nucleotide catabolic process | biological process | GO:0033122 | 4 | 3 | 16441 | 2455 |
MAPK7,EGLN1,TP53 |
| 1.182e-02 | -4.44 | calcium activated phosphatidylserine scrambling | biological process | GO:0061589 | 4 | 3 | 16441 | 2455 |
ANO9,ANO4,ANO6 |
| 1.182e-02 | -4.44 | neurotransmitter receptor metabolic process | biological process | GO:0045213 | 4 | 3 | 16441 | 2455 |
NRG1,FNTA,AGRN |
| 1.182e-02 | -4.44 | anoikis | biological process | GO:0043276 | 4 | 3 | 16441 | 2455 |
DAPK2,BMF,E2F1 |
| 1.182e-02 | -4.44 | negative regulation of phospholipid biosynthetic process | biological process | GO:0071072 | 4 | 3 | 16441 | 2455 |
PDGFA,SLC27A1,PDGFB |
| 1.182e-02 | -4.44 | oncostatin-M-mediated signaling pathway | biological process | GO:0038165 | 4 | 3 | 16441 | 2455 |
OSMR,IL6ST,LIFR |
| 1.182e-02 | -4.44 | negative regulation of trophoblast cell migration | biological process | GO:1901164 | 4 | 3 | 16441 | 2455 |
ARHGDIB,TIMP1,ACVR1C |
| 1.182e-02 | -4.44 | regulation of CD8-positive, alpha-beta T cell proliferation | biological process | GO:2000564 | 4 | 3 | 16441 | 2455 |
HLA-E,HLA-A,IRF1 |
| 1.182e-02 | -4.44 | sequestering of calcium ion | biological process | GO:0051208 | 4 | 3 | 16441 | 2455 |
CALR,HSP90B1,ATP7B |
| 1.183e-02 | -4.44 | actin filament binding | molecular function | GO:0051015 | 117 | 27 | 16491 | 2452 |
LASP1,USH1C,ADD1,CTNNAL1,SYNE3,CORO2A,UXT,SYNE2,EZR,PLS1,MICALL2,AIF1L,ANTXR1,SPTB,EGFR,PICK1,LCP1,CORO1B,SHROOM3,CORO1C,TRIOBP,ESPN,SPTBN5,MYH14,ARPC2,TLN2,SHROOM2 |
| 1.183e-02 | -4.44 | modification-dependent protein catabolic process | biological process | GO:0019941 | 456 | 86 | 16441 | 2455 |
FAF2,PSME2,CUL4B,PTTG1,FBXO2,CUL1,UBE2Z,PSME1,MVB12B,CCNB1,HDAC6,RAD23A,PSMD1,KIF14,PSMC2,PLK1,SIRT1,SEC61B,ERLEC1,FBXL16,ITCH,USP18,RNF11,CDC20,VPS4B,RNF165,AURKB,CCNF,CBL,RNF19B,CDK1,VCP,ZMPSTE24,TRIM9,DNAJC10,PSMD3,WFS1,WWTR1,AREL1,PSMC1,PINK1,HSP90B1,JKAMP,DNAJB2,CIT,PSMD7,PSMD10,ZNRF3,FBXO6,DNAJB9,WWP2,RNF128,FBXO7,NEK2,UBE2J1,PCYOX1,FBXL14,WWP1,USP38,USP1,STT3B,ZRANB1,MYLIP,PSMA5,UFD1L,PSMB4,USP31,AMFR,NUB1,UBE2A,FBXO8,FBXO9,TP53INP2,PSMA4,FBXO10,USP6,UBE2D2,AURKA,ARRB1,YOD1,NDFIP1,UBE2C,RNF146,USP16,FBXW5,USP43 |
| 1.186e-02 | -4.43 | vulva | COSMIC cancer mutations | vulva | 46 | 13 | 17775 | 2585 |
CDKN2C,PLCH1,CTNNB1,AKT1,FGFR2,PTEN,PIK3CA,TP53,SLC17A5,IDH1,FLT3,GNA11,EGFR |
| 1.188e-02 | -4.43 | phosphoprotein phosphatase activity | molecular function | GO:0004721 | 172 | 37 | 16491 | 2452 |
MTM1,DLGAP5,SSH1,PPM1J,UBASH3B,CTDSPL,PHLPP1,SBF1,DUSP5,EPM2A,PTEN,PALD1,PPP4R1,DLG1,DUSP10,PPP1CA,PTPRE,CTDSP2,CAMK2G,DUSP1,SSH3,PTPN18,PTPRU,PTPN9,DUSP23,PTPRH,DUSP4,CDC25C,PTPRF,PTPRJ,PLPP3,PHLPP2,PPM1H,PPP1CB,PPP2R5D,CPPED1,CTDSP1 |
| 1.189e-02 | -4.43 | lacrimal gland development | biological process | GO:0032808 | 7 | 4 | 16441 | 2455 |
FGFR2,RARG,SOX9,IGSF3 |
| 1.189e-02 | -4.43 | transformed cell apoptotic process | biological process | GO:0006927 | 7 | 4 | 16441 | 2455 |
DAB2IP,RHOB,FAS,BAX |
| 1.189e-02 | -4.43 | ether lipid metabolic process | biological process | GO:0046485 | 7 | 4 | 16441 | 2455 |
FAR2,FAR1,TMEM86B,AGPS |
| 1.189e-02 | -4.43 | male mating behavior | biological process | GO:0060179 | 7 | 4 | 16441 | 2455 |
GRN,PTEN,HEXB,GRIN1 |
| 1.189e-02 | -4.43 | cleavage furrow formation | biological process | GO:0036089 | 7 | 4 | 16441 | 2455 |
AURKB,RHOA,SNX9,SNX18 |
| 1.189e-02 | -4.43 | regulation of protein deubiquitination | biological process | GO:0090085 | 7 | 4 | 16441 | 2455 |
TRIM21,ITCH,DNAJB2,VCP |
| 1.189e-02 | -4.43 | kidney interstitial fibroblast differentiation | biological process | GO:0072071 | 7 | 4 | 16441 | 2455 |
ACTA2,HES1,OSR1,PDGFB |
| 1.189e-02 | -4.43 | intracellular cholesterol transport | biological process | GO:0032367 | 7 | 4 | 16441 | 2455 |
NPC2,LDLRAP1,ABCA1,ABCG1 |
| 1.189e-02 | -4.43 | cell proliferation involved in metanephros development | biological process | GO:0072203 | 7 | 4 | 16441 | 2455 |
OSR1,BMP7,GPC3,STAT1 |
| 1.189e-02 | -4.43 | RGS | prosite domains | PS50132 | 35 | 11 | 11866 | 1802 |
SNX13,RGS9,RGS12,ADRBK1,ARHGEF11,RGS3,RGS20,RGS5,GRK6,RGS14,ADRBK2 |
| 1.191e-02 | -4.43 | acute_leukaemia_of_ambiguous_lineage | COSMIC cancer mutations | acute_leukaemia_of_ambiguous_lineage | 61 | 16 | 17775 | 2585 |
AKT1,ASXL1,AMER1,ERBB2,NOTCH2,CBL,IDH1,FLT3,EGFR,CALR,CDKN2C,JAK1,CTNNB1,PTEN,PIK3CA,JAK3 |
| 1.191e-02 | -4.43 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage | 61 | 16 | 17775 | 2585 |
AKT1,ASXL1,AMER1,ERBB2,NOTCH2,CBL,IDH1,FLT3,EGFR,CALR,CDKN2C,JAK1,CTNNB1,PTEN,PIK3CA,JAK3 |
| 1.191e-02 | -4.43 | TSH signaling pathway | WikiPathways | WP2032 | 64 | 18 | 4455 | 729 |
KCNIP3,AKT1,RPS6KA1,PIK3R1,SCRIB,FOS,GNAS,RB1,JAK1,IGF1R,E2F1,PIK3CA,STAT1,CDKN1B,PDE4D,PLD1,RAP1GAP,MYL12B |
| 1.192e-02 | -4.43 | regulation of DNA-templated transcription, initiation | biological process | GO:2000142 | 31 | 10 | 16441 | 2455 |
CTNNBIP1,CTNNB1,WNT10B,THRA,PSMC2,MITF,GTF2F2,TWIST1,AHR,PSMC1 |
| 1.192e-02 | -4.43 | positive regulation of mesenchymal cell proliferation | biological process | GO:0002053 | 31 | 10 | 16441 | 2455 |
IRS2,PDGFA,CTNNB1,FGFR2,TBX1,SOX9,TBX18,SMO,STAT1,SHOX2 |
| 1.192e-02 | -4.43 | neuron maturation | biological process | GO:0042551 | 31 | 10 | 16441 | 2455 |
RB1,AGRN,CDKN1C,RET,NR4A2,NTN4,CNTNAP2,PICK1,RND1,FARP2 |
| 1.194e-02 | -4.43 | VAV1 (vav 1 guanine nucleotide exchange factor) | protein interactions | 7409 | 85 | 22 | 16036 | 2547 |
CASP3,RHOA,SUZ12,PIK3R1,ERBB2,RACGAP1,ARHGDIB,PRKCQ,TEC,CBL,MERTK,EGFR,ZYX,PLCG1,FYN,INSR,IL6ST,PLCG2,DNM2,ERBB3,SYK,TUBA4A |
| 1.195e-02 | -4.43 | BIRC2 (baculoviral IAP repeat containing 2) | protein interactions | 329 | 115 | 28 | 16036 | 2547 |
MAP3K3,CASP3,RHOA,HSP90B1,RIPK2,DNAJB2,DCAF7,TRAF2,CASP9,VPS4B,XIAP,EAF2,CD40,MXD1,EGFR,SH3KBP1,BCL10,CASP7,UBE2Q2,PRDX3,NFKBIA,FBXO7,UBE2D2,E2F1,UBE2J1,NOD2,TNFRSF12A,NFKB2 |
| 1.196e-02 | -4.43 | - | gene3d domains | 1.10.418.10 | 71 | 19 | 9988 | 1574 |
GAS2L1,LMO7,ASPM,ARHGEF7,IQGAP1,SYNE2,UTRN,PLS1,MICALL2,SPTB,LCP1,PLS3,SMTNL2,CLMN,LIMCH1,DIXDC1,SPTBN5,TAGLN2,IQGAP3 |
| 1.197e-02 | -4.43 | Regulation of signaling by CBL | REACTOME pathways | R-HSA-912631 | 18 | 7 | 8202 | 1235 |
FYN,PIK3CD,YES1,CBL,SYK,PIK3R1,PIK3CA |
| 1.197e-02 | -4.43 | KEEN_RESPONSE_TO_ROSIGLITAZONE_DN | MSigDB lists | KEEN_RESPONSE_TO_ROSIGLITAZONE_DN | 103 | 24 | 17758 | 2588 |
ANXA3,CLCN3,TXN,S100A11,DNAJB2,DSTN,SAT1,LITAF,EMP3,LCP1,BTG3,SPP1,PTEN,NPNT,MYLK,CD9,FXYD5,ACTA2,SERPINB6,NFKBIZ,IL10RB,CPE,S100A6,DUSP1 |
| 1.198e-02 | -4.42 | V$DBP_Q6 | MSigDB lists | V$DBP_Q6 | 239 | 48 | 17758 | 2588 |
LRRFIP2,TAB3,IL18,MORF4L2,GPSM2,MICALL2,SNX9,DENND2D,MNS1,NFAT5,ZNF385B,EPS8L2,GBX2,SCML1,FOXP2,ANKS1B,CALD1,BHLHE41,ZIC5,KLF3,MITF,SERINC2,H2AFY,DAB2IP,CRY2,GFI1,BTBD3,TGIF1,SMARCA2,KCNIP3,MGAT4B,DCHS1,ITPR3,EBF2,GPLD1,NFIX,BTG1,TAPBP,RBM47,SERPINA1,MYLK,E2F1,NR4A3,EFNA5,TOB1,RARG,KLF7,JARID2 |
| 1.198e-02 | -4.42 | ovary-carcinoma-adenocarcinoma | COSMIC cancer mutations | ovary-carcinoma-adenocarcinoma | 193 | 40 | 17775 | 2585 |
PAPSS2,CUL4B,TP53,NOTCH2,DPP8,CDKN2C,NUP210,CTNNB1,PTEN,TMEM62,PSMC2,MSH2,ADCK2,PIK3CA,LIMCH1,NOTCH3,CACNA1D,RASGRF1,TAF5,LCA5,ING1,AKT1,HMGN5,MMD,PIK3R1,AKAP3,IDH1,FOS,EGFR,PDE11A,GNAS,NCOA3,TBC1D17,SLC6A6,NEIL1,RBM47,JAK1,RHOBTB2,WDR91,PKD1L2 |
| 1.204e-02 | -4.42 | regulation of endothelial cell migration | biological process | GO:0010594 | 106 | 25 | 16441 | 2455 |
ANXA3,AKT1,RGCC,GATA3,VASH1,PDGFB,ETS1,BCAR1,EMP2,SRPX2,NRP2,HDAC9,GPLD1,PLCG1,PTGS2,SVBP,PDCD10,SP100,ACVRL1,PLPP3,PRCP,FGF18,DAB2IP,EFNA1,HSPB1 |
| 1.206e-02 | -4.42 | HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC | MSigDB lists | HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC | 46 | 13 | 17758 | 2588 |
PCNA,CXXC5,ST13,ITGB8,FOXM1,PPP1CB,TFAP2C,ARVCF,COX6C,PDGFB,TOB1,SEPHS1,GPX4 |
| 1.206e-02 | -4.42 | MODULE_259 | MSigDB lists | MODULE_259 | 46 | 13 | 17758 | 2588 |
FGFR2,PTK7,AXL,EPHA4,MYLK,DAPK1,ERBB2,PDGFRL,IL13RA1,ROR1,MERTK,LEPR,CDK5R1 |
| 1.207e-02 | -4.42 | MyD88-dependent toll-like receptor signaling pathway | biological process | GO:0002755 | 85 | 21 | 16441 | 2455 |
RIPK2,TNIP1,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 1.209e-02 | -4.42 | Activation of CaMK IV | REACTOME pathways | R-HSA-442745 | 4 | 3 | 8202 | 1235 |
CALM3,CALM2,CALM1 |
| 1.209e-02 | -4.42 | Plasmalogen biosynthesis | REACTOME pathways | R-HSA-75896 | 4 | 3 | 8202 | 1235 |
FAR2,FAR1,AGPS |
| 1.210e-02 | -4.41 | PDIA3 (protein disulfide isomerase family A member 3) | protein interactions | 2923 | 105 | 26 | 16036 | 2547 |
ADAM17,MFI2,AGRN,SUZ12,BACE1,ITGA6,ERO1A,TAP1,LOXL2,NANS,PLXNA1,HLA-A,EGFR,PDIA4,CALR,TAPBP,ITGA3,P4HB,CORO1C,ATP5H,PAK2,COL6A1,RPN2,TAGLN2,DCBLD1,ACOT7 |
| 1.210e-02 | -4.41 | Ndr | pfam domains | PF03096 | 4 | 3 | 16629 | 2504 |
NDRG2,NDRG3,NDRG1 |
| 1.210e-02 | -4.41 | RAI16-like | pfam domains | PF10257 | 4 | 3 | 16629 | 2504 |
FAM160B1,FAM160A1,FAM160A2 |
| 1.210e-02 | -4.41 | POLO_box | pfam domains | PF00659 | 4 | 3 | 16629 | 2504 |
PLK1,PLK2,PLK4 |
| 1.210e-02 | -4.41 | DUF1736 | pfam domains | PF08409 | 4 | 3 | 16629 | 2504 |
TMTC1,TMTC2,TMTC3 |
| 1.210e-02 | -4.41 | TIMP | pfam domains | PF00965 | 4 | 3 | 16629 | 2504 |
TIMP2,TIMP3,TIMP1 |
| 1.210e-02 | -4.41 | Carboxyl_trans | pfam domains | PF01039 | 4 | 3 | 16629 | 2504 |
PCCB,ACACB,MCCC2 |
| 1.210e-02 | -4.41 | Aldolase_II | pfam domains | PF00596 | 4 | 3 | 16629 | 2504 |
APIP,ADD3,ADD1 |
| 1.211e-02 | -4.41 | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | 87 | 21 | 17758 | 2588 |
TNIP1,RNF11,SAT1,FURIN,TAP1,SOD2,BCL2L1,SLC20A1,TNFSF9,CASP4,ICAM1,IER3,RCN1,MAPKAPK2,PTGS2,ETS2,NFKBIA,STAT1,TPST1,ACSL4,CITED2 |
| 1.211e-02 | -4.41 | SMITH_TERT_TARGETS_DN | MSigDB lists | SMITH_TERT_TARGETS_DN | 87 | 21 | 17758 | 2588 |
LAMP2,UGP2,AKT1,STAT4,ASAH1,ARHGDIB,OAT,TNFSF9,SIRPA,ABR,PGF,PCNA,FOSB,ALDH7A1,AHCY,SERPINB6,L1CAM,HSPA2,ALDH3A2,GM2A,FAH |
| 1.211e-02 | -4.41 | HALLMARK_IL6_JAK_STAT3_SIGNALING | MSigDB lists | HALLMARK_IL6_JAK_STAT3_SIGNALING | 87 | 21 | 17758 | 2588 |
PDGFC,IL15RA,IL13RA1,CBL,IL18R1,LEPR,FAS,SOCS3,IL17RB,IL1R1,ACVRL1,CSF1,IL6ST,STAT1,CD9,OSMR,IL17RA,TNFRSF12A,PIM1,IL10RB,IRF1 |
| 1.212e-02 | -4.41 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_UP | 187 | 39 | 17758 | 2588 |
HECA,MRC2,CAST,INPP5D,MAP1LC3B,STIL,LMNA,RAD23A,SGPL1,GNS,TTC21B,DAZAP1,NUP210,TMEM51,MANF,ETHE1,MAST4,TTLL1,XKR8,RAPGEF2,VPS4B,CBX6,HTATIP2,EMP3,YES1,H2AFV,PSMA4,ARHGEF26,ZMPSTE24,DCTN6,MID1IP1,PTK7,MATN2,S100A5,CCDC69,CLMN,GLB1,KLF11,HOXC13 |
| 1.212e-02 | -4.41 | GSE27786_LIN_NEG_VS_NKCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NKCELL_DN | 187 | 39 | 17758 | 2588 |
OTUD5,SORT1,DHPS,PBX3,TRAPPC8,ETS1,AIP,ICAM1,TMCC3,SNX13,ATP6V0B,RABEP2,CD22,TAX1BP3,ARL4D,DGKG,FAR1,PHKG2,CCDC88A,MYO5A,PARP9,HES1,TRIM8,PQLC3,TACC1,ATP1B1,ASB13,ITPR3,RNPEP,MAPKAPK2,TMEM50B,NAAA,JAK1,RCBTB2,NAB2,STAT1,RGS14,USF2,CTDSP1 |
| 1.212e-02 | -4.41 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN | 187 | 39 | 17758 | 2588 |
ARL4C,SEPP1,FAM101B,SLC20A1,DENND2D,APPBP2,ADD3,LRRC6,METTL7A,LMO4,CYP2S1,SGK1,USP38,PXMP4,MYLIP,ALS2CL,RASGRP1,PAQR7,SMARCA2,ING1,NRBF2,PLEKHO1,SYNE2,ATP1B1,GALNT7,TANC1,PDIK1L,STK17B,KCNMB4,MSL1,PPP2R5A,ACVRL1,SCG2,APPL2,NR4A3,CTSA,ATP1B3,RPS6KA3,KLF7 |
| 1.212e-02 | -4.41 | GSE27786_LIN_NEG_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_CD4_TCELL_UP | 187 | 39 | 17758 | 2588 |
MTM1,SPRED1,SORT1,ARAP3,SERPINE2,HEBP1,GPSM2,HDAC6,OAT,LMNA,HMGXB4,KIAA0895,P4HB,METTL7A,GALNS,CEP78,ZDHHC13,ECI2,STEAP3,STT3B,TFG,SYK,CKAP4,METAP2,TDP1,ATL1,SGCE,MRS2,CCNF,GLT8D2,RBL1,DBI,AMMECR1,DMWD,FHL1,SOX8,CCNB2,CD81,SRSF9 |
| 1.214e-02 | -4.41 | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | MSigDB lists | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | 61 | 16 | 17758 | 2588 |
PSMB4,NFKBIE,PSME2,PSMD7,PSMD10,CUL1,PSME1,PSMA4,BCL10,PSMD1,PSMD3,PSMC2,NFKBIA,MAP3K7,PSMC1,PSMA5 |
| 1.217e-02 | -4.41 | FERM_2 | prosite domains | PS00661 | 22 | 8 | 11866 | 1802 |
EPB41L5,FRMD4A,NF2,EZR,EPB41L4B,TLN2,EPB41L4A,FRMD4B |
| 1.217e-02 | -4.41 | positive regulation of proteolysis involved in cellular protein catabolic process | biological process | GO:1903052 | 166 | 36 | 16441 | 2455 |
DLGAP5,DNAJB2,PSME2,PSMD7,CUL1,PSMD10,PSME1,TRIB2,CCNB1,BCAP31,RB1,PSMD1,CTSC,PTEN,PSMC2,DAB2IP,OSBPL7,PSMA5,SOCS5,PLK1,AKT1,PSMB4,GCLC,NUB1,CDC20,PRICKLE1,RNF19B,CDK1,PSMA4,VCP,PSMD3,PLK2,AURKA,UBE2C,PSMC1,ESPL1 |
| 1.221e-02 | -4.41 | p38 MAPK signaling pathway | Pathway Interaction DB | p38_mkk3_6pathway | 29 | 12 | 2227 | 480 |
MAP3K3,CALM2,TAOK2,TXN,TRAF2,CCM2,CALM1,CALM3,MAPK11,MAP3K7,MAP3K5,MAP3K6 |
| 1.221e-02 | -4.41 | regulation of leukocyte proliferation | biological process | GO:0070663 | 194 | 41 | 16441 | 2455 |
CASP3,LGALS3,DHPS,IL15,INPP5D,HLA-E,ERBB2,IL18,CD274,PKN1,GSTP1,TNFSF9,EFNB1,HLA-A,CD46,RAC2,CTNNB1,IL6ST,BCL6,DLG1,IGFBP2,C10orf54,WNT3A,SLC39A10,SYK,HES1,CD55,RIPK2,ITCH,PDE5A,PRKCQ,CD40,IRS2,CSF1,ICOSLG,CD81,NDFIP1,JAK3,AHR,PRKAR1A,IRF1 |
| 1.223e-02 | -4.40 | V$BACH1_01 | MSigDB lists | V$BACH1_01 | 251 | 50 | 17758 | 2588 |
ENO2,CAPN12,NUAK1,CAMKK1,PSMD7,NDRG2,RNF182,FAM81A,LMNA,BMP2,SHC3,ABCA2,SGK1,TNFRSF12A,ABCD1,NTN4,MYH14,TAGLN2,PIM1,HCN3,TRAK2,TRIM8,MARK1,ELK3,LONRF3,CAPN6,CTNNAL1,DENND1B,RGAG1,KBTBD8,TMEM151A,STRADB,EMP3,SYP,COL7A1,ATP1B1,AIF1L,ZFAND5,PRX,GABARAPL1,TRIM47,MAP2,CAB39,DYSF,HS3ST3B1,HMGA1,UBE2C,FOXA1,MAMDC2,SNPH |
| 1.223e-02 | -4.40 | V$OCT1_Q6 | MSigDB lists | V$OCT1_Q6 | 251 | 50 | 17758 | 2588 |
PAX6,JKAMP,THRA,TSC22D3,IRX4,MRAS,SLC25A35,PPP2R3A,SLC9A7,NRP2,SCML1,FOXP2,PAK6,ADORA1,PTEN,RGS3,FLRT3,TSPAN13,PIK3CD,MANF,PDE4D,RIMS2,SCN3A,C9orf9,SOCS5,PDGFC,PLEKHA6,FZD4,ITCH,SH3BGRL,SERTAD4,STAT4,VAMP3,LDB2,ITPR3,EBF2,COL12A1,IRX3,DPYSL3,CXXC4,TSC1,PROM1,KLF12,GPRC5B,MAP2,PPP2R3C,TMOD2,SP6,TLL2,NR2C2 |
| 1.223e-02 | -4.40 | NrCAM interactions | REACTOME pathways | R-HSA-447038 | 7 | 4 | 8202 | 1235 |
ANK1,DLG3,NRP2,DLG1 |
| 1.223e-02 | -4.40 | CREB phosphorylation | REACTOME pathways | R-HSA-199920 | 7 | 4 | 8202 | 1235 |
MAPKAPK2,RPS6KA2,RPS6KA1,RPS6KA3 |
| 1.223e-02 | -4.40 | Apoptotic factor-mediated response | REACTOME pathways | R-HSA-111471 | 7 | 4 | 8202 | 1235 |
CASP3,CASP7,CASP9,XIAP |
| 1.223e-02 | -4.40 | Defects in biotin (Btn) metabolism | REACTOME pathways | R-HSA-3323169 | 7 | 4 | 8202 | 1235 |
PCCB,ACACB,MCCC2,MCCC1 |
| 1.223e-02 | -4.40 | Activation of NIMA Kinases NEK9, NEK6, NEK7 | REACTOME pathways | R-HSA-2980767 | 7 | 4 | 8202 | 1235 |
PLK1,CCNB1,CCNB2,CDK1 |
| 1.223e-02 | -4.40 | Defective HLCS causes multiple carboxylase deficiency | REACTOME pathways | R-HSA-3371599 | 7 | 4 | 8202 | 1235 |
PCCB,ACACB,MCCC2,MCCC1 |
| 1.224e-02 | -4.40 | CYSTEINE_TYPE_PEPTIDASE_ACTIVITY | MSigDB lists | CYSTEINE_TYPE_PEPTIDASE_ACTIVITY | 51 | 14 | 17758 | 2588 |
CASP3,UFD1L,CASP7,CAPN6,CTSB,CASP9,PDIA3,CAPNS1,USP1,LGMN,USP16,ATG4A,ATG4D,USP6 |
| 1.224e-02 | -4.40 | MODULE_399 | MSigDB lists | MODULE_399 | 51 | 14 | 17758 | 2588 |
ADORA1,TUBB4B,DAP,NFKBIA,BIK,STAT1,DAPK1,BNIP3L,EMP3,IL18,BCL2L1,CD40,BCAP31,AHR |
| 1.225e-02 | -4.40 | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | 56 | 15 | 17758 | 2588 |
BANK1,FUT8,TCF7,EGR3,CNTNAP2,EAF2,ATP1B1,NUCB2,MYBL1,DGKG,ALCAM,ABCA1,ATP10D,ATP2B1,SOCS5 |
| 1.225e-02 | -4.40 | Sad1_UNC | pfam domains | PF07738 | 7 | 4 | 16629 | 2504 |
SUN1,SUN2,SUN3,SUCO |
| 1.225e-02 | -4.40 | ACBP | pfam domains | PF00887 | 7 | 4 | 16629 | 2504 |
ACBD5,ECI2,ACBD3,DBI |
| 1.225e-02 | -4.40 | TGF_beta_GS | pfam domains | PF08515 | 7 | 4 | 16629 | 2504 |
TGFBR1,ACVR1,ACVRL1,ACVR1C |
| 1.226e-02 | -4.40 | organic acid catabolic process | biological process | GO:0016054 | 211 | 44 | 16441 | 2455 |
ALDH6A1,GCAT,AASS,CRYM,CPT2,HAL,ASL,MCCC1,LPIN3,OAT,ECI1,CYP39A1,CYP26A1,PCYOX1,ECI2,ALDH7A1,ABCD1,AHCY,GOT1,HMGCL,ACOX2,ACAD8,ETHE1,GAD1,MCCC2,FAH,CTH,CYP26B1,PRODH,PCCB,SHMT1,CCBL2,AMDHD1,CYP4F3,DDAH1,ALDH5A1,ACADSB,ABHD12,FAAH,ACAD10,PEX2,PLA2G15,ACADM,ACOT7 |
| 1.226e-02 | -4.40 | carboxylic acid catabolic process | biological process | GO:0046395 | 211 | 44 | 16441 | 2455 |
ALDH6A1,GCAT,AASS,CRYM,CPT2,HAL,ASL,MCCC1,LPIN3,OAT,ECI1,CYP39A1,CYP26A1,PCYOX1,ECI2,ALDH7A1,ABCD1,AHCY,GOT1,HMGCL,ACOX2,ACAD8,ETHE1,GAD1,MCCC2,FAH,CTH,CYP26B1,PRODH,PCCB,SHMT1,CCBL2,AMDHD1,CYP4F3,DDAH1,ALDH5A1,ACADSB,ABHD12,FAAH,ACAD10,PEX2,PLA2G15,ACADM,ACOT7 |
| 1.227e-02 | -4.40 | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | 170 | 36 | 17758 | 2588 |
GPR107,TBC1D1,DCAF7,PDIA5,MIER3,C1orf198,P2RX7,SLC1A3,ETS1,RAD23A,PIK3AP1,TFAP2A,ANKRD12,HSPA13,ACSL4,MCCC2,THRB,PPIF,DOCK4,EPB41L5,SEC61B,BCL9,NFE2L1,ARFRP1,GOLT1A,RNF19B,MPV17L2,CD83,MAPKAPK2,CASP7,ARHGEF19,NR4A3,DTX4,GLA,PSMC1,USP16 |
| 1.227e-02 | -4.40 | TTTTGAG,MIR-373 | MSigDB lists | TTTTGAG,MIR-373 | 216 | 44 | 17758 | 2588 |
FRMD4A,NF2,KLHL13,ZCCHC24,SOX9,ARFGEF1,C6orf106,KCTD12,MPP5,PRR7,PSIP1,CHST2,SSX2IP,VPS26A,MYO5C,WDFY1,WDR44,IMPAD1,EPB41L4B,C9orf72,KDELR1,PHF20L1,FBLN5,MBP,MLEC,C2orf69,SRSF5,PDIK1L,ADRBK2,DAG1,ARF4,VCP,SERTAD2,SLC4A4,FGFR2,PTER,SETD3,AMMECR1,C1orf21,DCUN1D1,HDAC1,KLF5,NDFIP1,TOB1 |
| 1.232e-02 | -4.40 | calmodulin binding | molecular function | GO:0005516 | 178 | 38 | 16491 | 2452 |
SCN5A,ADD1,CAMKK1,IQGAP1,STRN4,CAMK1D,MYO5C,DAPK2,SNTA1,ADD3,CEP97,CALD1,KCNN4,DAPK1,MYH14,IQGAP3,PHKA2,PHKG2,CAMK2G,MYO5A,ATP2B1,CTH,MYO5B,CAMSAP3,CASK,MAPKAPK3,ASPM,SNTB2,GRIN1,SPA17,SNTB1,USP6,MAPKAPK2,MAP2,MYLK,GEM,ITPKA,NRGN |
| 1.232e-02 | -4.40 | EPH-Ephrin signaling | REACTOME pathways | R-HSA-2682334 | 95 | 23 | 8202 | 1235 |
MYL9,ARHGEF28,RHOA,ARHGEF7,EPHA4,GRIN1,YES1,EPHA1,MYL12A,EFNB1,RASA1,EPHA10,FYN,LIMK1,PAK2,EFNA5,EFNA1,MYH14,EPHB4,ARPC2,TIAM1,MYL12B,NGEF |
| 1.233e-02 | -4.40 | calcium-dependent phospholipid binding | molecular function | GO:0005544 | 55 | 15 | 16491 | 2452 |
PLA2G4A,DOC2A,ANXA3,MCTP1,SYT7,MCTP2,DYSF,ANXA9,SYT13,SYTL4,TC2N,SYTL3,SYTL2,ANXA11,ESYT2 |
| 1.233e-02 | -4.40 | steroid hormone receptor activity | molecular function | GO:0003707 | 55 | 15 | 16491 | 2452 |
THRB,NKX3-1,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,GPER1,NR3C2,NR2C1,RARG,PAQR7,NR2C2 |
| 1.234e-02 | -4.40 | INTRINSIC_TO_MEMBRANE | MSigDB lists | INTRINSIC_TO_MEMBRANE | 1288 | 216 | 17758 | 2588 |
LAMP1,BCAM,ACVR1,GRIK2,SLC25A13,EPHA4,SDC1,SLC20A1,SLC9A7,GRM5,HTR1D,ABCD4,ZYX,TGFBR3,ENTPD4,TM9SF2,STIM1,LMAN2L,IL6ST,SLC44A1,STEAP2,FUT1,ABCA2,CLDN4,TRPC1,TACSTD2,PXMP4,TRAM1,IL10RB,IL1RAP,SGCE,CD55,MCTP1,ACVR1C,ROR1,SLC17A5,SLC25A5,PLEKHB1,EDNRA,HS6ST1,ENPP1,KCNMB4,SLC25A4,GDE1,KCNK1,DOLPP1,ATP7B,MADD,POMT1,F2RL1,SLC31A2,CD99,FXYD3,ABCG2,NOTCH2,B4GALT4,MERTK,TSPAN7,ITGA3,LYPD3,SLC16A6,CD22,KCNN4,ICAM5,OPN3,FXYD5,SORL1,CD70,CNGA1,NCAM1,SLC12A2,CKAP4,TMED2,KDELR1,ABCC1,NAGPA,FADS2,QSOX1,PODXL2,PCDH1,MFI2,MMD,RGMB,PTPRH,CALCRL,EPHA1,BCL2L13,STEAP1,PTPRF,IL1R1,GNAS,MMP15,GABRD,SCARB2,INSR,SLC4A4,ITPR1,MPP2,SLC4A3,OSMR,EFNA1,ATP1B3,TRPC3,DRD1,SLC2A4,IL15,ST14,SLC2A8,CD82,PKP2,P2RX7,IL27RA,IL13RA1,SLC7A2,DDR1,FLT3,EMP2,BCAP31,KTN1,CD46,ATP6V0B,SMO,VAT1,ECE1,EPHB4,NOTCH3,TSPAN1,LMAN1,F2R,CLCN3,PTPRU,FZD4,PTGER4,SLC11A2,IGSF8,ATP1B1,CD40,DAG1,FZD7,TAPBP,PTPRJ,RTN4RL1,ATP1A1,PTK7,WFS1,AXL,SLC9A6,MMP17,PEX2,SECTM1,EFNA5,HS3ST3B1,LIFR,ABCA1,GOLIM4,MPZL1,TRAPPC10,TSPAN15,CD63,MAN1A2,BACE1,MCTP2,FLOT1,GABRG2,SELL,CYB561,TGFBR1,JAG2,SBF1,KCNC4,EFNB1,LBR,ICAM1,XPR1,SLC9A2,FZD6,NEO1,M6PR,IL17RB,ADORA1,ITGB8,MGAT1,KCNK5,GPC3,BAX,SLC44A2,TMBIM6,TSPAN13,ERBB3,SGCB,SLC35A1,SLC16A5,ATP2B1,GCNT1,P2RX4,SYPL1,ADAM17,AMFR,MPP1,GRIN1,VAMP3,CD83,BCL10,GALNT3,CNTNAP1,PROM1,ACVRL1,SPINT2,ABCB1,RYK,PGRMC1,PKD2,FZD5,CD81,CD33,GOLGB1 |
| 1.234e-02 | -4.40 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D | 257 | 51 | 17758 | 2588 |
GSDMD,CD99,LTBP1,MZT1,LGALS3,TRIP10,ITPR2,SNX9,TIPRL,SLC9A2,ARHGEF10L,B3GALNT1,RAB15,TGFBR3,ADRBK1,CABP1,OSBPL3,FCHO1,DUSP10,PHKA2,PLCB2,SGCB,ETV4,CPE,TIAM1,TMCC2,MBP,CITED4,DENND1B,DUSP23,CYS1,RNF165,CBX6,DIAPH2,CALCRL,RUNX3,CYFIP2,ZDHHC3,ONECUT1,DNAJC10,MID1IP1,ALDH5A1,SERPINA1,NR1D2,DNM1L,APPL2,PPP1CB,OSMR,PLOD3,HOOK1,SEMA3A |
| 1.234e-02 | -4.40 | V$AP2_Q6_01 | MSigDB lists | V$AP2_Q6_01 | 257 | 51 | 17758 | 2588 |
KIF3C,SPRED1,KCNAB3,CERCAM,TEX2,EGR3,OSR2,GRK6,PKN1,BAHD1,PDGFB,HOXB2,PHF1,NEO1,TFAP4,RNF220,ZNRF2,CDK16,TACC2,ATP5H,BCL6,CNNM4,DLG3,NCOA2,DNAI1,KCNJ12,TMEM68,C6orf1,CXXC5,CELSR2,MGAT4B,TFAP2C,SRRM3,COL12A1,MAP1B,RASGRP2,PGF,CAMK2N2,PPP2R5A,SYT7,PTK7,CGREF1,ARAP1,SH3BP4,ADIPOR1,ITPKA,STARD13,RAD21,DMPK,FGD1,RGMA |
| 1.234e-02 | -4.39 | Galactose metabolism | KEGG pathways | hsa00052 | 30 | 10 | 6908 | 1076 |
PGM1,GALK1,GAA,UGP2,PFKL,MGAM,AKR1B1,GLB1,GALM,GLA |
| 1.234e-02 | -4.39 | Galactose metabolism | KEGG pathways | ko00052 | 30 | 10 | 6908 | 1076 |
PGM1,GALK1,GAA,UGP2,PFKL,AKR1B1,MGAM,GLB1,GALM,GLA |
| 1.237e-02 | -4.39 | meninges-meningioma | COSMIC cancer mutations | meninges-meningioma | 335 | 64 | 17775 | 2585 |
NF2,RET,TP53,ERBB2,BAIAP3,ITPR2,OSR2,TMEM19,CDKN2C,ZYX,RPS6KA2,CTNNB1,WDR44,TACC2,SMO,POLL,PIK3CA,IRF2,DAB2IP,ARNT2,WBP4,TIAM1,CYP1B1,MYO5B,AKT1,CR2,IDH1,SLC25A5,PPP2R5A,PTK7,ATP7B,PSMD3,MYLK,TSPAN18,SIPA1L1,EPB41L4A,FRMD6,SOX9,NOTCH2,JAG2,AIP,GNS,CALR,FOXP2,DOPEY2,PDCD10,ADD3,MLPH,PTEN,PCYOX1,ERBB3,HSPA13,KNTC1,RIMS2,SYPL1,PIK3R1,COL7A1,BBS2,GNA11,EGFR,GNAS,TSC1,FGFR2,NAB2 |
| 1.239e-02 | -4.39 | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP | 193 | 40 | 17758 | 2588 |
TSC22D3,XYLT1,SELL,PBX3,TRMT2B,DDR1,KHNYN,CD22,AIM1,MTMR10,SORL1,DUSP10,KLF9,PIK3CD,PHKA2,DUSP1,POU6F1,TGIF1,ARAP2,MMD,TEP1,CXorf57,UTRN,CR2,ADRBK2,CD83,ENDOD1,BTG1,BANK1,ETS2,CDK19,PHLPP2,STAT6,DTX4,SPRY4,TRAF5,NR3C2,KLF7,PHC1,FAM134B |
| 1.239e-02 | -4.39 | GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDM_DN | 193 | 40 | 17758 | 2588 |
SORT1,CCDC109B,TMEM184B,AGRN,ADD1,FAM134A,TAP1,GPR180,F11R,DHRS3,ARHGEF40,TMEM63A,CTNNB1,ARSG,FRYL,PAPSS1,TNPO2,GYS1,ABCD1,MDFIC,OAS3,DGKG,PAQR7,TNIP1,ASXL1,BCL9,TFAP2C,SNX12,ARHGAP35,CRTC2,LDLRAP1,CHMP4B,TMOD2,SERPINB6,ALG2,FHL1,HMGA1,RGS14,MYL12B,TMEM131 |
| 1.239e-02 | -4.39 | GSE27786_NKTCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_NKTCELL_VS_NEUTROPHIL_DN | 193 | 40 | 17758 | 2588 |
DOC2A,SORBS3,TMEM63A,SLC16A6,GALNS,CST3,PRC1,KLC3,ABCD1,ACOX2,SEMA3G,ARMCX6,OSBPL7,IL1RAP,SNED1,TRAK2,MAP3K3,SUSD3,KRT80,CHSY3,UFD1L,VPS4B,STRADB,NKAIN1,CAPNS1,LDB2,ZFAND5,FZD7,CMTM7,RASGRP2,SOCS3,NAAA,LDLRAP1,PPP2R5A,PELI2,TMEM30A,AURKA,ACADM,CPEB2,KLF7 |
| 1.239e-02 | -4.39 | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN | 193 | 40 | 17758 | 2588 |
EPAS1,MRPS15,HEXB,MCOLN3,HMGN3,TEX2,RASGRP3,GTF3A,MGST2,ERP29,COL6A1,VAT1,CKS1B,AHCY,CCDC88A,FAM69A,PCCB,MRPS33,ALDH2,TIMP2,MMD,GUSB,MPP1,MRPS35,ESYT1,SLC25A5,IDH1,SESN1,TP53I3,PRDX4,GNAS,AMZ2,CCDC6,PTER,PRPS2,MDH1,ACADM,HSPB1,CHPT1,DLAT |
| 1.239e-02 | -4.39 | GSE17721_LPS_VS_CPG_24H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_CPG_24H_BMDM_DN | 193 | 40 | 17758 | 2588 |
SPC25,TRIP10,FHDC1,STRN4,ABCG2,TGFBR1,MRAS,CNTNAP2,PJA2,BMP2K,COX7A2,RAC2,SLC16A6,LMO4,SLC44A1,UBE2J1,TMEM51,TWIST1,PDIA6,MSH6,SMC4,QSOX1,ADAM17,ALDH2,PSRC1,KIF20A,SLC37A1,ITCH,C3orf52,LITAF,CDK1,NIN,RPL12,SWAP70,UEVLD,RND3,NAB2,ARFGAP3,CCNB2,TMEM131 |
| 1.239e-02 | -4.39 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP | 193 | 40 | 17758 | 2588 |
KIF3C,KLF2,RECQL,PAPSS2,TBC1D1,CYP2J2,TRAF2,FAM134A,SPR,PHF1,BMP2K,PDIA4,AKIRIN1,SNX13,ST5,CNTRL,BCL6,ERCC2,NR2C1,MX1,TIMP2,CAPN6,CTNNAL1,RC3H2,NFE2L1,SP4,BSDC1,TCN2,SGPP1,RASGRP2,TSC1,NCOA3,RPL12,COQ10A,NR1D2,NR4A3,CANT1,RPL22,ST3GAL1,ABCG1 |
| 1.239e-02 | -4.39 | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDM_UP | 193 | 40 | 17758 | 2588 |
TPRN,DLGAP5,CKAP2,CUL4B,HABP4,TESK2,AES,CMTM6,TMPRSS4,XPR1,CAPN2,PCNA,BDH1,N4BP3,IL31RA,TRIM3,RPN2,ACOX2,GCNT1,MBP,PTPN18,LAP3,LGALS8,MPP1,LPGAT1,OXR1,DBR1,CCDC34,FAM73B,RNPEP,CDK1,ENDOD1,ANKRD10,GNAS,MSL1,SLC25A4,KBTBD2,ARRB1,PDXK,RBM43 |
| 1.239e-02 | -4.39 | GSE29618_PDC_VS_MDC_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DN | 193 | 40 | 17758 | 2588 |
SLC25A24,LGALS3,IQGAP1,BLVRB,EFHD2,CUL1,NDRG2,IL13RA1,GSTP1,LMNA,TIMP1,CST3,BCL6,SGK1,OAS3,TIPARP,ALDH3A2,TMBIM1,ATP2B1,PPIF,IFITM3,S100A4,PLEKHO1,PTGER4,EMP3,ARHGDIB,BLVRA,ADRBK2,RHOB,PTGS2,RCBTB2,RIN3,NOD2,RAB31,ARRB1,KLF11,SERPINB6,SERPINB1,AHR,CD33 |
| 1.239e-02 | -4.39 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN | 193 | 40 | 17758 | 2588 |
GALK1,CMAS,SDC4,ERI2,C5orf30,RACGAP1,BCL2L1,PSMD1,PPP1R10,PSMC2,CKS1B,BUB1,USP1,KNTC1,FAR2,SGCB,SMC4,TBC1D10B,FAH,SEPHS1,CYP1B1,GCNT1,ZWINT,CTNNAL1,HTATIP2,GGH,PKMYT1,CCNF,GTF2A2,IDH1,PSMA4,KDM4D,SLCO4A1,FAM64A,PRDX3,P4HA2,CSTF2,DONSON,CCNB2,ACOT7 |
| 1.239e-02 | -4.39 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 193 | 40 | 17758 | 2588 |
KLF2,RECQL,PAPSS2,NQO1,ATP9A,TRAF2,FAM134A,STRN4,SPR,FAM101B,SPSB1,PHF1,CHPF,AKIRIN1,ST5,RPS6KA2,ADORA1,CA2,RALGPS2,FOSB,ERCC2,NOTCH3,MAP3K3,MX1,COL6A2,TIMP2,CTNNAL1,DIAPH2,TYSND1,TCN2,BSDC1,ULK2,NFIX,NCOA3,RPL12,NR1D2,CANT1,PITPNA,SERPINI1,ABCG1 |
| 1.239e-02 | -4.39 | GSE17721_CTRL_VS_CPG_2H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_2H_BMDM_UP | 193 | 40 | 17758 | 2588 |
ADD1,EPAS1,HEBP1,RALBP1,FAM134A,ERCC6L,MGST2,CDIPT,EXT2,SIX4,SLC25A45,KCNN4,BDH1,DLG1,PCYOX1,FAM63A,TMEM51,TRIM3,ABCD1,HMGCL,CNOT6L,MPHOSPH9,CAMK2G,MED22,THRB,FOPNL,MPP1,ACO1,FBXO8,SNAPC2,C4orf27,ANKRD10,PIAS3,MTFMT,SLC25A4,PPP2R5A,TMEM30A,PNPLA6,AGBL5,STARD3NL |
| 1.239e-02 | -4.39 | GSE17721_LPS_VS_POLYIC_6H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDM_DN | 193 | 40 | 17758 | 2588 |
GRN,LAMP1,LASP1,TRAPPC10,IL15RA,ITGA6,HEXB,DOPEY2,PQLC2,KCNN4,SGK1,TNFRSF12A,TMEM37,PHKA2,PXMP4,PLCB2,NAGA,POU6F1,SUN2,SLC37A1,SNTB2,CASP9,BNIP3L,HTATIP2,ITPR3,DOCK5,KDM3A,CDK1,FUCA1,SCARB2,CCDC6,STK38,CORO1C,PPP2R4,PDXK,HMGA1,TOB1,IRF1,FAM134B,ABCG1 |
| 1.239e-02 | -4.39 | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN | MSigDB lists | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN | 193 | 40 | 17758 | 2588 |
LAMP1,FAM189A2,BLVRB,ARL4C,SMARCAL1,MRAS,DSE,SDC1,BARD1,FAM46C,RSAD1,NCS1,ICAM1,TMCC3,PLS3,GNS,CALR,WEE1,SLC16A6,BUB1,SGCB,CPE,TSPAN33,TLE6,FADS2,TGIF1,KCNIP3,SLC39A8,STMN3,PDK3,ARSK,MYOM1,TCEAL8,DPYSL3,HLA-B,POPDC3,DNM1L,SECTM1,FAM3C,SLC31A2 |
| 1.239e-02 | -4.39 | GSE17721_4_VS_24H_CPG_BMDM_UP | MSigDB lists | GSE17721_4_VS_24H_CPG_BMDM_UP | 193 | 40 | 17758 | 2588 |
OTUD5,MTM1,MRC2,PARP12,FRMD6,HAL,OSGIN2,IL18,CCNL1,SNN,FAM46C,CYP26A1,PDGFA,RPS6KA2,OXCT1,BHLHE41,RANBP1,MITF,FAM102A,ATG4D,PCCB,RFK,LGALS8,DSTN,SEPT6,BCL9,FHL2,CLSTN1,EMP3,PLS1,SAV1,SPTLC2,SHROOM3,TRIM69,PVRL2,MATN2,ARF6,NDE1,TRAF5,TC2N |
| 1.239e-02 | -4.39 | GSE360_CTRL_VS_L_DONOVANI_DC_UP | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_DC_UP | 193 | 40 | 17758 | 2588 |
FAM169A,GNPDA1,RPS6KA1,HLA-E,ARHGEF7,INPP5D,XYLT1,CTDSPL,PBX3,TRAPPC8,TRIB2,VASH1,SEPP1,GBX2,RASSF8,PCNA,RPS6KA2,ITGA3,PLCG2,SORL1,ACTA2,AHCY,MED22,ATP2B1,PCCB,ZWINT,MPP1,SH3BGRL,S100A4,BLVRA,ALDH5A1,PRCP,UTP14C,GLB1,ARHGAP4,CBX5,USF2,LTA4H,TOB1,CD33 |
| 1.240e-02 | -4.39 | POLO_BOX | prosite domains | PS50078 | 4 | 3 | 11866 | 1802 |
PLK1,PLK2,PLK4 |
| 1.240e-02 | -4.39 | COA_CT_CTER | prosite domains | PS50989 | 4 | 3 | 11866 | 1802 |
PCCB,ACACB,MCCC2 |
| 1.240e-02 | -4.39 | TIMP | prosite domains | PS00288 | 4 | 3 | 11866 | 1802 |
TIMP3,TIMP2,TIMP1 |
| 1.240e-02 | -4.39 | LAMP_3 | prosite domains | PS51407 | 4 | 3 | 11866 | 1802 |
LAMP2,LAMP1,LAMP3 |
| 1.240e-02 | -4.39 | COA_CT_NTER | prosite domains | PS50980 | 4 | 3 | 11866 | 1802 |
PCCB,ACACB,MCCC2 |
| 1.240e-02 | -4.39 | AMOP | prosite domains | PS50856 | 4 | 3 | 11866 | 1802 |
SUSD2,MUC4,ISM1 |
| 1.245e-02 | -4.39 | forebrain development | biological process | GO:0030900 | 356 | 69 | 16441 | 2455 |
EMX1,CASP3,NF2,STIL,PHLDA1,TP73,TTC21B,APLP2,CTNNB1,CDH1,TACC2,DPYSL2,KIF14,LHX6,ALDH1A3,SMO,DAB2IP,DIXDC1,NOTCH3,ZBTB18,BTBD3,TFAP2C,ARHGAP35,MDK,FYN,AXL,NRG1,NRGN,ANXA3,SCN5A,ADGRG1,CNTNAP2,ETS1,PGAP1,MECOM,GBX2,FOXP2,BMP2,GATA2,PTEN,PRKG1,BAX,WNT3A,HES1,RHOA,TACC1,ASPM,RAPGEF2,GRIN1,BBS2,NFIB,CDK5R1,EGFR,PITX2,TSC1,FAT4,TWSG1,HTT,FGFR2,PHLPP2,DBI,RYK,NR4A3,E2F1,NR4A2,NDE1,WDR62,SEMA3A,DRD1 |
| 1.248e-02 | -4.38 | Phox | interpro domains | IPR001683 | 51 | 14 | 18293 | 2672 |
SNX8,SNX13,SNX18,SGK3,SNX16,PLD2,PIK3C2B,PLD1,SNX9,SNX10,PXDC1,SNX12,SNX30,SNX7 |
| 1.256e-02 | -4.38 | MYC (v-myc avian myelocytomatosis viral oncogene homolog) | protein interactions | 4609 | 595 | 115 | 16036 | 2547 |
TXN,NLRX1,AASS,FAM131C,SLC25A13,XYLT1,TP53,CUL1,DNAJB11,TAF6L,MICALL2,OAT,AIFM2,PCBP1,MXD1,FANCI,SH3KBP1,TP73,SAP130,RCN1,PAK6,WEE1,ARL1,PSMC2,TUBG1,RPN2,NOTCH3,PPP1CA,TIAM1,TUBA4A,SULF2,PLK1,SMARCA2,TAF5,PTPN9,PBK,CDYL,TFAP2C,ERBB2IP,CDK1,ADRBK2,ARF4,IRS2,NEIL1,PPP2R5A,RBL1,PSMD3,MYLK,PRKCDBP,HDAC1,ADIPOR1,CTNND1,EFNA5,KPNA2,HSPB1,COPG1,BIN1,LMTK3,SDC4,RASSF7,PKN1,EFNB1,LMNA,ELF3,MYO5C,TOP2A,RB1,IRAK1,TAF1B,CYR61,CDK16,NECAB3,KNDC1,PAK2,TFAP2A,MSH2,NEK2,CTPS1,PRC1,TRIM21,BRD7,PIM1,ALPK1,IQGAP3,MAPK7,CTSD,PHKG2,RIMS2,PSMA5,RBMS2,MSH6,CAMK2G,CKAP4,SMC4,RASGRF1,DDB2,PSMB4,CALM1,FHL2,FBXO8,YES1,PSMA4,TXK,NCOA3,NUCB1,NMI,CDCA7L,RIN3,SH3BP4,E2F1,PIAS2,PLOD3,AFAP1,XDH,RAD21 |
| 1.257e-02 | -4.38 | ATAGGAA,MIR-202 | MSigDB lists | ATAGGAA,MIR-202 | 98 | 23 | 17758 | 2588 |
SPRED1,BAG4,ACVR1,NDRG1,IQGAP1,RNF11,ERBB2IP,CBL,FAM46C,HOXB2,LBR,PGAP1,APPBP2,RASA1,DNAJC10,BTG1,HLF,KLF12,PTEN,SNX16,ARSB,RPS6KA3,CCDC88A |
| 1.257e-02 | -4.38 | MCCLUNG_CREB1_TARGETS_UP | MSigDB lists | MCCLUNG_CREB1_TARGETS_UP | 98 | 23 | 17758 | 2588 |
CD99,CXXC5,TTC39B,STMN3,SYP,TP53INP2,NDRG3,FOS,LMNA,CDK14,PLS3,NOV,SIPA1L2,CTGF,ACYP1,H1F0,FAM3C,SERPINI1,CPLX1,ASH2L,ARF6,ACOT7,TUBA4A |
| 1.258e-02 | -4.38 | MAN2A1 (mannosidase, alpha, class 2A, member 1) | protein interactions | 4124 | 10 | 5 | 16036 | 2547 |
NAAA,CD55,PLAUR,CAPN1,FLOT1 |
| 1.258e-02 | -4.38 | HPCAL4 (hippocalcin like 4) | protein interactions | 51440 | 10 | 5 | 16036 | 2547 |
CYP1A1,FBXL16,TTC12,FAM131C,TSC22D3 |
| 1.258e-02 | -4.38 | IFIH1 (interferon induced, with helicase C domain 1) | protein interactions | 64135 | 10 | 5 | 16036 | 2547 |
IDE,PTEN,TSPAN6,PIAS2,NLRC5 |
| 1.258e-02 | -4.38 | FRK (fyn-related Src family tyrosine kinase) | protein interactions | 2444 | 10 | 5 | 16036 | 2547 |
RB1,FYN,PTEN,PCBP1,EGFR |
| 1.258e-02 | -4.38 | GNGT1 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1) | protein interactions | 2792 | 10 | 5 | 16036 | 2547 |
GNAS,GNB5,GNB2,NAGA,PLEKHB1 |
| 1.258e-02 | -4.38 | Mzt1 (mitotic spindle organizing protein 1) | protein interactions | 76789 | 10 | 5 | 16036 | 2547 |
TUBG1,MZT2A,MZT1,LGALS3BP,TUBGCP6 |
| 1.258e-02 | -4.38 | CASP12 (caspase 12 (gene/pseudogene)) | protein interactions | 100506742 | 10 | 5 | 16036 | 2547 |
RIPK2,TRAF2,CASP9,XIAP,NOD2 |
| 1.258e-02 | -4.38 | CLCN3 (chloride channel, voltage-sensitive 3) | protein interactions | 1182 | 10 | 5 | 16036 | 2547 |
CLCN3,LGALS3,LGALS8,HSPB1,LYPD3 |
| 1.259e-02 | -4.37 | odontogenesis of dentin-containing tooth | biological process | GO:0042475 | 75 | 19 | 16441 | 2455 |
SCN5A,RUNX2,NF2,ITGA6,LRP4,PPARA,JAG2,PITX2,BMP2,CA2,CTNNB1,STIM1,FAM20C,BMP7,TBX1,SMO,BAX,HDAC1,CNNM4 |
| 1.261e-02 | -4.37 | ZHANG_BREAST_CANCER_PROGENITORS_UP | MSigDB lists | ZHANG_BREAST_CANCER_PROGENITORS_UP | 401 | 75 | 17758 | 2588 |
GRHL2,FAM199X,KIF2C,DDR1,APPBP2,WEE1,KCTD15,SESN3,CCNA2,NFU1,ARNT2,SLC39A10,FGFR1OP2,CTH,FIGNL1,ASXL1,PBK,SERTAD4,PANK1,ANLN,PLEKHB1,PRIM1,WDR11,ACYP1,RBL1,ZNF367,RELL1,SGOL1,DLAT,RRAGD,MPZL1,DEPDC1,TRAPPC10,ITGA6,EPS8,ERI2,CDCA8,COL4A5,NDUFA4,GPSM2,SYDE2,NEO1,TOP2A,E2F7,RNF128,OXCT1,ALG13,FAM13B,PCYOX1,BRD7,AHCY,USP1,TSPAN13,BUB1,MOXD1,NUP85,SMC4,MOB4,MRPS33,SHMT1,ARAP2,MBNL3,KBTBD8,POLD3,PROM1,DCK,PRPS2,UBE2D2,AURKA,CSTF2,MDH1,HOOK1,AHR,MELK,RAD21 |
| 1.262e-02 | -4.37 | intracellular protein transport | biological process | GO:0006886 | 724 | 130 | 16441 | 2455 |
EXPH5,UNC93B1,FAF2,GRIK2,TAP1,TRAPPC8,SYTL4,HDAC6,SNX9,ERP29,PICK1,ZFYVE16,NAPG,RAB15,AP1M2,SNX16,RAB20,CTTN,TRAM1,MYRIP,VPS11,ARFRP1,KIF13A,ICMT,RAB2B,VCP,OPTN,GNPTAB,KPNA2,GGA1,PEX6,SEC61G,RAB23,RAB6A,APBA1,PGAP1,LMNA,ATG4A,CALR,SNX18,KIF13B,RPL39,FBXO7,PRKCI,SRP54,SORL1,SYTL3,NUP85,RIMS2,TMED2,KDELR1,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,STRADB,ZDHHC3,RHOB,STX3,SCARB2,TIMM8A,HTT,ZDHHC20,NFKBIA,RAB31,ZDHHC7,CTSA,LTBP2,JAK3,TOB1,DRD1,EHD1,TP53,BCAP31,SYTL2,APPBP2,ZFYVE9,ZDHHC12,ZDHHC23,BCL6,TNPO2,RPN2,IFIT1,RAB27B,LMAN1,F2R,CHP1,ATG4D,SNX8,SEC23A,SEC61B,AKT1,RAB38,ATP1B1,DAG1,ATP10D,PEX5,DDOST,STX10,PEX2,RAB29,CHMP4B,RPL22,COPG1,TAOK2,HSP90B1,PDIA3,IFT27,AIP,VPS26A,ZDHHC21,SNX13,ANK1,MLPH,ADORA1,PPP1R10,RPGR,SYK,HES1,RAB3B,PIK3R1,VAMP3,PRICKLE1,RAB3IP,BBS2,RGPD5,RPL12,ARFGAP3,SPCS3 |
| 1.262e-02 | -4.37 | MULLIGHAN_MLL_SIGNATURE_1_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_1_DN | 228 | 46 | 17758 | 2588 |
CD99,BIN1,TRIM24,AGRN,SERPINE2,CTDSPL,MCTP2,C5orf30,ISYNA1,BAIAP3,EGR3,HOXB2,TSPAN7,SLC9A3R2,MYO5C,BTG3,FUT2,MCF2L,DAPK1,TNPO2,IFIT1,LOXL1,MAST4,EEF1D,FAH,STAT4,PRKCQ,ATP1B1,SRSF5,YES1,LHFPL2,RHOB,PGF,HSF4,MDK,TIMP3,HLF,JAK1,AREG,SIPA1L1,ABCB1,FAM117A,CLMN,EGFL7,ITGAV,ISOC1 |
| 1.263e-02 | -4.37 | HEMATOPO_REC_L_F2 | prosite domains | PS01353 | 7 | 4 | 11866 | 1802 |
OSMR,LEPR,LIFR,IL6ST |
| 1.263e-02 | -4.37 | GOLOCO | prosite domains | PS50877 | 7 | 4 | 11866 | 1802 |
GPSM2,RGS12,RGS14,RAP1GAP |
| 1.263e-02 | -4.37 | GS | prosite domains | PS51256 | 7 | 4 | 11866 | 1802 |
TGFBR1,ACVR1,ACVR1C,ACVRL1 |
| 1.263e-02 | -4.37 | ACB_2 | prosite domains | PS51228 | 7 | 4 | 11866 | 1802 |
ACBD5,ECI2,ACBD3,DBI |
| 1.265e-02 | -4.37 | central_nervous_system-brain-glioma-ependymoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma | 23 | 8 | 17775 | 2585 |
NF2,CTNNB1,AKT1,PTEN,PIK3CA,TP53,IDH1,EGFR |
| 1.265e-02 | -4.37 | skin-face-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-face-malignant_melanoma-lentigo_maligna | 23 | 8 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3CA,ERBB2,FLT3,EGFR |
| 1.267e-02 | -4.37 | CYTOSKELETAL_PROTEIN_BINDING | MSigDB lists | CYTOSKELETAL_PROTEIN_BINDING | 159 | 34 | 17758 | 2588 |
SORBS1,ADD1,SSH1,ARFGEF1,RACGAP1,SORBS3,SPTB,ATG4A,KIF5B,FLII,ANK1,CENPJ,CALD1,TUBGCP6,DLG1,FXYD5,ESPN,MYLIP,CCDC88A,ATG4D,SUN2,UXT,EZR,PLS1,ANLN,EGFR,MAPK8IP1,GABARAPL1,SHROOM3,HTT,TMOD2,PKD2,NDE1,SHROOM2 |
| 1.270e-02 | -4.37 | THUM_SYSTOLIC_HEART_FAILURE_UP | MSigDB lists | THUM_SYSTOLIC_HEART_FAILURE_UP | 389 | 73 | 17758 | 2588 |
LAMP1,PLA2G4A,CNOT8,EPHA4,ETNK1,PKP2,FAM198B,PHLDA1,CD46,SS18,RALB,ANKRD12,LMAN1,SCARA3,PDIA6,LOXL1,TMEM43,LAP3,FOPNL,UTRN,EZR,HTATIP2,ARHGDIB,ZFAND5,LCP1,UEVLD,PLK2,TSPAN18,STAT1,EFNA5,ARF6,CTHRC1,HSP90B1,PACSIN2,MRPL44,PLSCR4,SERPINE2,SCOC,CTSB,MIER3,NOTCH2,SRPX2,M6PR,DIRAS3,RAC2,CTSC,HLA-C,SGCB,TMED2,CRTAP,HP1BP3,SYPL1,PDGFC,ADAM17,RHOA,B3GNT2,VAMP3,BTN3A2,DPP9,CALCRL,LEPR,FAS,ARHGAP24,MAPKAPK2,TMEM50B,DDAH1,SCARB2,KBTBD2,PGRMC1,ERAP1,LTBP2,RARG,ARHGEF9 |
| 1.274e-02 | -4.36 | DAGKa | smart domains | SM00045 | 10 | 5 | 9131 | 1455 |
DGKH,DGKG,DGKQ,DGKE,DGKA |
| 1.274e-02 | -4.36 | IG_FLMN | smart domains | SM00557 | 10 | 5 | 9131 | 1455 |
TRIM3,TRIM2,AREL1,KDELC2,TRIM45 |
| 1.277e-02 | -4.36 | V$NFY_C | MSigDB lists | V$NFY_C | 234 | 47 | 17758 | 2588 |
IER5L,ACVR1,PAX6,SPC25,SUZ12,HLA-F,ETV5,KIF23,TESK2,DNAJB11,RACGAP1,SEPT4,BAHD1,IFT27,SPTB,M6PR,GPC3,FUT8,DUSP10,RPN2,TSPAN13,TECR,PXMP4,ANO4,NCAM1,RAG1,DLG3,MED30,CKS2,MAP3K3,GCA,MLEC,KIF20A,PIK3R1,FXR2,LDB2,TYSND1,ACYP1,PEX2,WDR19,SPAG7,FAM117A,HDAC1,AGFG2,UBE2C,CBX5,ESPL1 |
| 1.278e-02 | -4.36 | glycosphingolipid metabolic process | biological process | GO:0006687 | 70 | 18 | 16441 | 2455 |
UGT8,HEXB,ASAH1,ARSK,CPTP,B4GALNT1,ALDH5A1,ITGB8,ARSG,A4GALT,BAX,CTSA,GLB1,GLA,ARSB,ST3GAL1,NAGA,GM2A |
| 1.278e-02 | -4.36 | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN | MSigDB lists | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN | 293 | 57 | 17758 | 2588 |
MYL9,FAM171B,SLC2A4,SORBS1,NDRG1,TSC22D3,LMCD1,GATA3,LGI3,DNER,TSPAN7,BEX2,MOCS1,HDAC9,SUSD2,FOXP2,SIPA1L2,CEP97,RGS12,CALD1,FLRT3,REEP1,ACTA2,IGFBP2,TLN2,NCAM1,CITED2,DNAI1,TMCC2,MMD,S100A4,PIK3R1,COL7A1,DNAJB14,MYOM1,MUM1L1,CACHD1,SLCO4A1,HLF,BANK1,PROM1,CTNS,PDLIM3,SLC4A4,WIPI1,FGFR2,ISM1,CGREF1,MYLK,EIF4EBP2,FHL1,TANC2,WDR91,ZC3HC1,PKIA,PROM2,DMPK |
| 1.280e-02 | -4.36 | regulation of cell cycle G2/M phase transition | biological process | GO:1902749 | 55 | 15 | 16441 | 2455 |
CCND1,CCNA2,CCNB3,WNT10B,KIF14,VPS4B,H2AFY,PRKCQ,FHL1,CDK1,MIIP,HSPA2,FANCI,PKIA,IER3 |
| 1.280e-02 | -4.36 | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | MSigDB lists | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | 23 | 8 | 17758 | 2588 |
PDGFA,CTHRC1,RAB3B,COL6A2,FXYD3,COL6A1,GEM,FOS |
| 1.280e-02 | -4.36 | MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_DN | MSigDB lists | MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_DN | 23 | 8 | 17758 | 2588 |
GAS2L1,CD46,CTNNB1,PVRL2,CKAP2,AXL,PNPLA6,DUSP1 |
| 1.280e-02 | -4.36 | IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_UP | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_UP | 23 | 8 | 17758 | 2588 |
RMND5A,RGPD5,PTPN18,FAM189A2,PCBP3,ZSCAN12,SULT2B1,S100A2 |
| 1.280e-02 | -4.36 | REACTOME_G0_AND_EARLY_G1 | MSigDB lists | REACTOME_G0_AND_EARLY_G1 | 23 | 8 | 17758 | 2588 |
CCNE2,PCNA,CCNA2,RBL1,MYBL2,E2F1,HDAC1,CDK1 |
| 1.280e-02 | -4.36 | CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN | MSigDB lists | CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN | 23 | 8 | 17758 | 2588 |
ATP6V0B,PAFAH1B3,TUBB4B,PFKL,CTSA,TNFRSF12A,GOT1,TSPAN1 |
| 1.280e-02 | -4.36 | OSADA_ASCL1_TARGETS_DN | MSigDB lists | OSADA_ASCL1_TARGETS_DN | 23 | 8 | 17758 | 2588 |
IGFBP6,CDH1,AXL,NRG1,KLF5,DUSP1,CYP1B1,SOCS3 |
| 1.280e-02 | -4.36 | GRADE_COLON_CANCER_DN | MSigDB lists | GRADE_COLON_CANCER_DN | 32 | 10 | 17758 | 2588 |
RMND5A,CNTNAP1,SRPX,SLC4A4,METTL7A,PLOD2,SGK1,ELK1,SEPP1,TP53INP2 |
| 1.280e-02 | -4.36 | POS_HISTAMINE_RESPONSE_NETWORK | MSigDB lists | POS_HISTAMINE_RESPONSE_NETWORK | 32 | 10 | 17758 | 2588 |
CAMK2N2,FBLN5,IL15,TAX1BP3,H2AFY,LOXL1,TIAM1,TSPAN7,ARF4,GCNT1 |
| 1.280e-02 | -4.36 | MODULE_28 | MSigDB lists | MODULE_28 | 32 | 10 | 17758 | 2588 |
PSMD1,PSMB4,PSMD3,PSMC2,PSMD7,PSMD10,PSME1,PSMC1,PSMA4,PSMA5 |
| 1.280e-02 | -4.36 | MODULE_366 | MSigDB lists | MODULE_366 | 32 | 10 | 17758 | 2588 |
TSC1,SHMT1,CTNS,OSBPL3,EPHA1,PLXNA1,ZMYM1,DHRS3,RAP1GAP,CPPED1 |
| 1.289e-02 | -4.35 | positive regulation of JUN kinase activity | biological process | GO:0043507 | 65 | 17 | 16441 | 2455 |
FZD4,TRAF2,EPHA4,PKN1,MAP3K6,MAP3K11,MAP3K9,KIAA1804,MDFIC,DAB2IP,MAP3K5,FZD5,MAP3K7,GAB1,SYK,DVL2,MDFI |
| 1.289e-02 | -4.35 | ribonucleoside diphosphate metabolic process | biological process | GO:0009185 | 65 | 17 | 16441 | 2455 |
PGM1,CASK,ENO2,PFKFB2,MPP1,OGDHL,AK4,PKM,NUDT16,ENTPD4,PFKL,DLG1,MPP2,DHTKD1,AK3,DLG3,PPP2R5D |
| 1.289e-02 | -4.35 | regulation of muscle cell differentiation | biological process | GO:0051147 | 150 | 33 | 16441 | 2455 |
RBM24,THRA,SOX9,FLOT1,GDF15,IL18,MORF4L2,HDAC9,NEO1,BMP2,NOV,CTNNB1,BHLHE41,TNPO2,MAPK11,WNT3A,FLOT2,MBNL3,PRICKLE1,ILK,BTG1,FGFR2,TBX1,SETD3,HDAC1,NRG1,GPER1,MAP3K5,SOX8,SHOX2,DMPK,MAPK12,EHD1 |
| 1.289e-02 | -4.35 | negative regulation of multi-organism process | biological process | GO:0043901 | 150 | 33 | 16441 | 2455 |
SIGIRR,NLRX1,TRIM5,APOBEC3H,FBLN1,TFAP4,FAM111A,TIMP1,SP100,TSPAN6,TRIM21,IFIT1,OAS3,APOBEC3G,TRIM62,MX1,TRIM8,APOBEC3D,TNIP1,PLSCR1,ACVR1C,IFITM3,MICB,ITCH,TRIM35,ARHGDIB,PRDX4,TRAF3IP1,NOD2,STAT1,HDAC1,RNASEL,ITGAV |
| 1.290e-02 | -4.35 | chondroitin sulfate proteoglycan metabolic process | biological process | GO:0050654 | 60 | 16 | 16441 | 2455 |
B3GALT6,CHSY3,HSPG2,AGRN,SDC4,XYLT1,HEXB,PXYLP1,DSE,SDC1,CHPF,GPC3,IMPAD1,XYLT2,CSGALNACT1,ARSB |
| 1.290e-02 | -4.35 | establishment of chromosome localization | biological process | GO:0051303 | 60 | 16 | 16441 | 2455 |
PSRC1,DLGAP5,VPS4B,CDCA8,KIF2C,CCNB1,SPDL1,RB1,KIF14,CDCA5,FAM83D,CHMP4B,KIF22,CENPE,NDE1,GEM |
| 1.290e-02 | -4.35 | chromosome localization | biological process | GO:0050000 | 60 | 16 | 16441 | 2455 |
PSRC1,DLGAP5,VPS4B,CDCA8,KIF2C,CCNB1,SPDL1,RB1,KIF14,CDCA5,FAM83D,CHMP4B,KIF22,CENPE,NDE1,GEM |
| 1.294e-02 | -4.35 | negative regulation of immune effector process | biological process | GO:0002698 | 96 | 23 | 16441 | 2455 |
CD55,LGALS3,NLRX1,ITCH,MICB,HLA-E,SERPINB9,TAP1,ABR,HLA-A,CD46,HLA-B,TSPAN6,TRAF3IP1,BCL6,NOD2,TMBIM6,DUSP10,C10orf54,IFIT1,NDFIP1,JAK3,SOCS5 |
| 1.298e-02 | -4.34 | Actinin_actin-bd_CS | interpro domains | IPR001589 | 23 | 8 | 18293 | 2672 |
SYNE2,UTRN,CLMN,PLS1,SPTBN5,SPTB,LCP1,PLS3 |
| 1.299e-02 | -4.34 | RNF7 (ring finger protein 7) | protein interactions | 9616 | 52 | 15 | 16036 | 2547 |
TRIM8,CASP7,TCEB2,MKRN3,CUL4B,PLA2G15,UBE2D2,CUL1,UBE2Q1,GEM,ASB13,SPSB1,ITM2C,VCP,SOCS3 |
| 1.299e-02 | -4.34 | EPHA2 (EPH receptor A2) | protein interactions | 1969 | 52 | 15 | 16036 | 2547 |
PIFO,CDK17,ITGA3,ADRBK1,RBL1,PSME2,PIK3R1,CLDN4,EFNA5,EFNA1,ITGAV,CBL,TIAM1,RASA1,EGFR |
| 1.300e-02 | -4.34 | MAP kinase kinase kinase activity | molecular function | GO:0004709 | 27 | 9 | 16491 | 2452 |
MAP3K3,TAOK2,KIAA1804,MAP3K11,MAP3K9,MAP3K5,MAP3K7,MAP3K6,EGFR |
| 1.300e-02 | -4.34 | phosphatidylinositol phosphate phosphatase activity | molecular function | GO:0052866 | 27 | 9 | 16491 | 2452 |
MTM1,INPP5E,PTEN,OCRL,TMEM55B,INPP5D,INPP4B,PIKFYVE,EPM2A |
| 1.301e-02 | -4.34 | neuron migration | biological process | GO:0001764 | 112 | 26 | 16441 | 2455 |
MARK1,CELSR2,ASPM,RAPGEF2,GATA3,DNER,CDK5R1,FYN,ITGA3,CTNNB1,CDKL5,GATA2,AXL,PEX2,MATN2,LHX6,KIAA0319,BAX,PRKG1,TWIST1,NR4A2,NTN1,NDE1,SEMA3A,POMGNT2,DRD1 |
| 1.302e-02 | -4.34 | centriole | cellular component | GO:0005814 | 103 | 24 | 17570 | 2579 |
CEP89,POC1B,CCSAP,CNTROB,CCNF,NUBP1,STIL,NIN,CEP162,DZIP1L,TOP2A,CCDC92,HTT,CENPJ,PLK2,PLK4,CAPG,TUBG1,AURKA,RP2,CEP41,CFAP20,WDR62,MPHOSPH9 |
| 1.304e-02 | -4.34 | V$NRF2_Q4 | MSigDB lists | V$NRF2_Q4 | 246 | 49 | 17758 | 2588 |
GAS2L1,UNKL,PPP4R4,TNRC6C,LRRFIP2,FRMD4A,CAPN12,HSPG2,NUAK1,BLVRB,ETV5,PSMD7,NDRG2,LGI3,RAB6A,APBA1,PRR7,SRPX2,BEX2,VPS26A,PER2,TFAP4,PSMD1,NECAB3,SLC16A6,LMO4,ABCA2,ADAM15,ABCD1,MYH14,PDE4D,WBP4,TUBA4A,MDFI,TGIF1,CAPN6,KBTBD8,TMEM151A,ATP1B1,SFXN5,VCP,PRX,TMEM54,LIMK1,CAB39,SH3BGRL2,DRP2,RTN3,RARG |
| 1.304e-02 | -4.34 | V$FOXO4_02 | MSigDB lists | V$FOXO4_02 | 246 | 49 | 17758 | 2588 |
CDKN1C,CHCHD7,THRA,ETV5,ARFGEF1,TEX2,RAB6A,PHLPP1,SEPT4,SEPP1,KREMEN1,ZFYVE9,TFAP4,FOXP2,FRY,ITGB8,IL6ST,FAM63A,DIXDC1,CITED2,NTN1,TIAM1,SCN3A,DOCK4,TGIF1,TRIM8,CXXC5,KIF20A,NR3C1,ASXL1,NUB1,LRRC1,KDM3A,NFIX,GNAS,XKRX,CRTC2,PITX2,INSR,TBC1D17,KLF12,VSIG10,KLF5,NRG1,NR4A2,EFNA1,LEMD1,MAFF,EHD1 |
| 1.306e-02 | -4.34 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | 165 | 35 | 17758 | 2588 |
CHCHD7,HAPLN3,CYP2J2,ITGA6,SELL,RHPN2,C3orf18,HPCAL4,SCML1,IGF1R,IL6ST,BDH1,PASK,TPST1,SNED1,SUSD3,CD55,DCHS1,STRADB,EPHA1,MEST,SFXN5,LDLRAP1,NGFRAP1,SPINT2,EFNA1,SOX8,CEP41,NDFIP1,NR3C2,PKIA,KLF7,ARHGEF4,FAM134B,PCSK5 |
| 1.306e-02 | -4.34 | V$E2F_Q2 | MSigDB lists | V$E2F_Q2 | 165 | 35 | 17758 | 2588 |
SORT1,MPZL1,PPM1J,ADO,FBXO2,GATA3,ZFYVE9,VPS26A,TFAP2E,ARHGEF10L,CTNNBIP1,ZCCHC17,CYR61,USP1,AK3,TINAGL1,RASGEF1A,GFI1,GPR161,PCGF5,CELSR2,CLSTN1,VAMP3,ATP1B1,RNF19B,PDIK1L,MAPKAPK2,DDAH1,PPP2R5A,COL13A1,CCDC6,C1orf21,ADIPOR1,FBXO44,C1orf43 |
| 1.306e-02 | -4.34 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | 77 | 19 | 17758 | 2588 |
PCOLCE,COL6A2,GUSB,CALM1,TP53,COL18A1,CALM3,KDELR3,MEST,NPDC1,CALM2,SRPX,NPNT,COL6A1,MAOA,ADAM15,PRKCDBP,CRTAP,DMPK |
| 1.307e-02 | -4.34 | WWP1 (WW domain containing E3 ubiquitin protein ligase 1) | protein interactions | 11059 | 71 | 19 | 16036 | 2547 |
PRKAA2,KLF2,PHF20L1,RUNX2,FAM189A2,RNF11,EZR,DAG1,RASA1,SCNN1A,PTEN,STAT6,TMEM51,TFAP2A,ARRDC1,KLF5,ASH2L,WWP1,HSPB1 |
| 1.307e-02 | -4.34 | BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B) | protein interactions | 701 | 71 | 19 | 16036 | 2547 |
PLK1,ZWINT,UGP2,PTTG1,CDC20,NDC80,NUF2,AURKB,PSMA4,TP73,CCNA2,RPL39,HDAC1,BUB1,CENPE,SGOL1,UBE2C,MAD2L1BP,HSPB1 |
| 1.307e-02 | -4.34 | SOCS3 (suppressor of cytokine signaling 3) | protein interactions | 9021 | 71 | 19 | 16036 | 2547 |
TCEB2,BIK,YES1,TXNDC11,LEPR,MAPK8IP1,RASA1,EGFR,BCL10,IRS2,INSR,JAK1,IGF1R,IL6ST,NFKBIA,MAPK11,MAP3K7,MAP3K5,JAK3 |
| 1.307e-02 | -4.34 | FOS (FBJ murine osteosarcoma viral oncogene homolog) | protein interactions | 2353 | 126 | 30 | 16036 | 2547 |
ELK4,SIRT1,PRKAA2,RUNX2,NQO1,TSC22D3,RPS6KA1,ELK1,PRKACA,FOS,ETS1,EGFR,LMNA,MAP1B,OPTN,RB1,NCOA3,RPS6KA2,ETS2,CABP1,MITF,STAT1,GTF2F2,GLB1,MAP3K7,MAPK7,USF2,MAFF,NCOA2,EEF1D |
| 1.313e-02 | -4.33 | NKX3-1 (NK3 homeobox 1) | protein interactions | 4824 | 34 | 11 | 16036 | 2547 |
HSP90B1,LMCD1,HMG20B,HDAC1,STMN3,RABL6,RARG,SP4,SP5,CKAP4,CHPF |
| 1.313e-02 | -4.33 | BUB1 (BUB1 mitotic checkpoint serine/threonine kinase) | protein interactions | 699 | 34 | 11 | 16036 | 2547 |
PLK1,ZWINT,SPC25,CDC20,NDC80,HDAC1,RABL6,NUF2,BUB1,CENPE,CDK1 |
| 1.313e-02 | -4.33 | GMPS (guanine monophosphate synthase) | protein interactions | 8833 | 34 | 11 | 16036 | 2547 |
RCN1,PRKAG2,ENO2,AGPAT2,PPME1,CTPS1,EFHD2,AHCY,GLO1,FBXO6,HSPB1 |
| 1.313e-02 | -4.33 | RXRB (retinoid X receptor beta) | protein interactions | 6257 | 34 | 11 | 16036 | 2547 |
THRB,NCOA3,NR3C1,TACC2,THRA,ZDHHC12,FLYWCH2,PPARA,NR4A2,RARG,NR2C2 |
| 1.313e-02 | -4.33 | LIMK2 (LIM domain kinase 2) | protein interactions | 3985 | 34 | 11 | 16036 | 2547 |
RCN1,MBP,ATP1A1,HSP90B1,SSH1,LIMK1,SLC25A13,HSPB1,HIPK3,LMNA,TUBA4A |
| 1.317e-02 | -4.33 | regulation of protein transport | biological process | GO:0051223 | 725 | 130 | 16441 | 2455 |
EXPH5,TXN,LGR4,CACNA2D2,GATA3,IL18,ITPR2,SYTL4,BARD1,SLC8B1,ERP29,CABP1,KCNS3,MYRIP,RASGRP1,VPS11,ACVR1C,BNIP3L,NBPF3,EZR,PRKAR2B,SLC25A5,LCP1,SLC25A4,DNM1L,RAB11FIP1,NOD2,F2RL1,DDX58,NFKBIE,HLA-E,RAB23,FBLN1,IL18R1,ANO1,RAC2,PFKL,KCNN4,SORL1,MDFIC,CACNA1D,WNT3A,MAPK7,MDFI,GCC2,KIF20B,EGFR,CDK5R1,GNAS,TMEM30A,ITPR1,NFKBIA,OSCP1,YOD1,TMEM173,IQGAP1,THRA,ERBB2,P2RX7,CD274,MICALL2,APC2,PRKACA,BCAP31,PER2,NOV,SP100,CDH1,DACT1,SMO,TWIST1,DAB2IP,MYT1,F2R,CHP1,SIRT1,BAG4,ERLEC1,PFKFB2,DMTN,PTGER4,PRKCQ,ITPR3,CD40,SNX12,FZD7,IRS2,PTGS2,WWTR1,RAB29,NRG1,EFNA5,PRKAR1A,TCAF1,PINK1,TRAF2,PSMD10,HMGN3,TGFBR1,NEO1,WWP2,CARD8,OXCT1,CDK16,LLGL2,BMP7,FAM20B,UBE2J1,TMBIM6,MAPK11,SYK,HES1,RHOA,SYBU,PIK3R1,RGCC,VAMP3,LITAF,PIM3,GPLD1,NUCB1,BANK1,SYT7,ARRB1,PKD2,SPCS3,GPER1,FZD5,NDFIP1,PKIA |
| 1.318e-02 | -4.33 | regulation of peptidyl-threonine phosphorylation | biological process | GO:0010799 | 36 | 11 | 16441 | 2455 |
PLK1,CALM2,SPRED1,PRKAG2,RIPK2,BMP7,DMTN,CALM1,CAB39,CALM3,SPRY2 |
| 1.318e-02 | -4.33 | negative regulation of actin filament depolymerization | biological process | GO:0030835 | 36 | 11 | 16441 | 2455 |
SWAP70,PLEKHH2,ADD1,DMTN,EPS8,CAPG,TRIOBP,SPTBN5,TMOD2,SHROOM2,SPTB |
| 1.318e-02 | -4.33 | mitotic metaphase plate congression | biological process | GO:0007080 | 36 | 11 | 16441 | 2455 |
PSRC1,KIF14,CDCA5,VPS4B,CDCA8,KIF22,CHMP4B,CENPE,KIF2C,SPDL1,CCNB1 |
| 1.318e-02 | -4.33 | activation of JUN kinase activity | biological process | GO:0007257 | 36 | 11 | 16441 | 2455 |
KIAA1804,MAP3K11,MAP3K9,MDFIC,DAB2IP,MAP3K5,PKN1,GAB1,MAP3K6,SYK,MDFI |
| 1.320e-02 | -4.33 | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP | MSigDB lists | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP | 188 | 39 | 17758 | 2588 |
SCN5A,TMEM184B,IL15RA,VANGL1,EPHA4,C6orf106,SNN,SLC20A1,ICAM1,APPBP2,VASP,PSMD1,XYLT2,FAM20B,MITF,RAB20,MANF,PTPRE,RASGRP1,DUSP1,ENPP4,TNIP1,PAPD7,UBE2A,SAV1,TAPBP,CASP7,STAT1,NR4A3,DGAT2,TRIOBP,PPP1CB,CHMP4B,GDF11,IFIH1,ST3GAL1,MAFF,EHD1,IRF1 |
| 1.320e-02 | -4.33 | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | 188 | 39 | 17758 | 2588 |
GRN,HECA,ANKRD13D,BMF,S100A11,RPS6KA1,TSC22D3,SMARCAL1,IL27RA,FAM78A,TMEM170B,GSTP1,PCBP1,CXCL16,RGS12,WDR44,BRI3,PIK3CD,PPP1CA,CTDSP2,TMBIM1,MAP3K3,TIMP2,TACC1,PLEKHO1,SERTAD3,TTC7A,UBAC1,RUNX3,ICMT,ATXN7L3,SH2D3C,ARAP1,RAB31,ZDHHC7,B4GALT3,PLIN3,CTDSP1,DIS3L |
| 1.320e-02 | -4.33 | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDM_DN | 188 | 39 | 17758 | 2588 |
SPC25,DHPS,ABCG2,DNAJB11,IL18,FTH1,F11R,CAMK1D,GPSM2,KREMEN1,MAGOHB,ZCCHC17,RNF128,FAM13B,ATP13A3,SLC44A1,OPN3,TMEM51,UBE2J1,ACSL4,SMYD5,CASD1,B3GNT2,TNIP1,PBK,ITCH,STK17B,CDK1,ARHGAP24,FNTA,SLC4A4,MADD,DGAT2,HDAC1,CLMN,KPNA2,MRPS28,PLD1,SGOL1 |
| 1.320e-02 | -4.33 | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDM_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDM_DN | 188 | 39 | 17758 | 2588 |
GOLIM4,TXN,DEPDC1,DNAJC3,MRAS,NUCB2,NTAN1,TMEM19,BEX2,MDM1,TM9SF2,CTGF,NPNT,DPYSL2,N4BP3,MAPK11,TSPAN13,RP2,AK3,TECR,WBP4,IL1RAP,MPP1,CCDC34,HMG20B,FAM73B,CD83,ZMPSTE24,CNOT2,FNTA,AXL,FGF18,CLMN,PKD2,TMOD2,CHMP4B,NFKBIZ,SERPINI1,NDFIP1 |
| 1.325e-02 | -4.32 | postsynapse | cellular component | GO:0098794 | 351 | 67 | 17570 | 2579 |
GRIK2,EPHA4,FBXO2,ERBB2,KCTD12,PJA2,PRR7,PICK1,GRM5,NCS1,CABP1,DLG1,DNM2,PPP1CA,CTTN,DLG3,F2R,DMTN,UTRN,CLSTN1,PRKAR2B,TANC1,DAG1,ARF4,FYN,ATP1A1,GRID2IP,MAP2,SIPA1L1,ITPKA,RGS14,NRGN,LZTS1,FARP1,CPEB4,LRP4,EPS8,STRN4,GABRG2,SLC1A3,SNTA1,ANK1,ADD3,ADORA1,PTEN,ANKS1B,MAGEE1,MAP3K7,CAMK2G,DLGAP1,P2RX4,MOB4,SHARPIN,GRIN1,SCRIB,CDK5R1,MAP1B,IL1R1,GABRD,HTT,ITPR1,NETO2,ARRB1,GRIN2D,GPER1,RUSC1,DRD1 |
| 1.330e-02 | -4.32 | heart morphogenesis | biological process | GO:0003007 | 212 | 44 | 16441 | 2455 |
GAA,ACVR1,GRHL2,SOX9,GATA3,PKP2,TGFBR1,NOTCH2,DHRS3,STIL,BMP2,TGFBR3,SETDB2,CYR61,MEGF8,SMO,ADAM15,TWIST1,EPHB4,WNT3A,CITED2,CPE,DVL2,HES1,ASXL1,DCHS1,FHL2,WHSC1,SAV1,NPHP3,ILK,LEMD2,PITX2,INSR,FAT4,FGFR2,TBX1,NRG1,PKD2,PLXND1,EFNA1,ZMIZ1,SHOX2,EGLN1 |
| 1.330e-02 | -4.32 | DARWICHE_PAPILLOMA_RISK_HIGH_UP | MSigDB lists | DARWICHE_PAPILLOMA_RISK_HIGH_UP | 137 | 30 | 17758 | 2588 |
SUN1,NEK4,GALK1,GCLM,TXN,S100A11,IFITM3,TRAF2,RACGAP1,KLK6,MRPS18A,PRRC1,EXT2,ART5,SPNS3,RAB2B,ICAM1,TP73,CXCL16,IDE,PFKL,MGAT1,RPL39,AXL,CMPK2,LRIF1,CHPT1,UBE2C,CCDC38,EEF1D |
| 1.330e-02 | -4.32 | BMI1_DN.V1_DN | MSigDB lists | BMI1_DN.V1_DN | 137 | 30 | 17758 | 2588 |
COL9A3,TRIM2,CDH22,S100A4,SH3BGRL,ESRP1,BLVRB,EPHA4,SOD2,PDE5A,NDRG2,PLS1,NENF,SEPP1,IDH1,FOS,SFXN1,IL1R1,CTNNBIP1,DCTN6,HS6ST1,SCNN1A,CA2,METTL7A,TFAP2A,CAB39,HOXB13,TSPAN1,IFI6,ISOC1 |
| 1.332e-02 | -4.32 | regulation of sequence-specific DNA binding transcription factor activity | biological process | GO:0051090 | 363 | 70 | 16441 | 2455 |
SIGIRR,TRIM5,THRA,TAF6L,CAMK1D,SP100,SIVA1,SMO,DAB2IP,TWIST1,NFKB2,DVL2,CTH,CHP1,CYP1B1,SIRT1,TRIM8,RIPK2,AKT1,FZD4,ITCH,PRKCQ,ERBB2IP,SAV1,GTF2A2,CD40,C3orf33,WFS1,NOD2,TRAF5,DDX58,ANXA3,PINK1,TAB3,TRAF2,DAP,PSMD10,FZD6,ICAM1,WWP2,CTNNBIP1,RB1,IRAK1,IGF1R,PTEN,BMP7,PRKCI,SGK3,TRIM21,SGK1,MAPK11,PIM1,WNT3A,MAP3K7,GFI1,SYK,TRIM62,WNT10B,RGCC,FOS,BCL10,CRTC2,PRDX3,PLPP3,NFKBIA,NLRC5,PIAS2,ARRB1,FOXA1,EGLN1 |
| 1.334e-02 | -4.32 | cerebellum | COSMIC cancer mutations | cerebellum | 801 | 139 | 17775 | 2585 |
PPP4R4,ACVR1,LGR4,RET,ARFGEF1,VARS2,CAMK1D,ITPR2,SNX9,TMC1,DENND2D,SLC9A7,SH3KBP1,GRM5,DAPK2,CTNNB1,PAPSS1,ANKFN1,MITF,PIK3CA,ANO4,CPE,MCTP1,KIF13A,LDB2,PPP1R14C,IDH1,TRAM2,NOD2,GLA,GLCCI1,DDX58,RUNX2,LRRFIP2,TBC1D1,ITGA6,ABCG2,SLC36A4,CNTNAP2,ANO1,BMP2,CA2,NOXA1,PIK3AP1,FAM189A1,MSH2,PRKG1,MAP3K9,CACNA1D,CHSY3,FADS2,RGMB,PARD3B,FBXO8,ZSCAN12,KDM3A,ANTXR1,EGFR,PDE11A,GNAS,FECH,PLEKHH2,PRKAG2,C1orf21,ALPK3,SEMA3A,DOCK9,MTM1,PAPSS2,GRHL2,NF2,TP53,P2RX7,SLC7A2,CYP39A1,ZNF385B,CDS1,MUC16,SP100,SMO,GYS1,DAB2IP,PDE4D,SCN2A,ZNF365,SOAT1,AKT1,UTRN,PRKCQ,CDCA2,ASB13,TANC1,DOCK5,ALCAM,ATP10D,EBF2,OSBPL2,STAT6,MAOA,NRG1,ARNT,COBL,ZC3HC1,PRKAR1A,DENND5B,FAM134B,KLHL13,PARP14,ATP9A,PBX3,SELL,GABRG2,INTS8,DNAH3,ZDHHC21,CD109,ITGB8,CTSC,ARSG,PTEN,GPC3,KIAA0319,RPGR,MSH6,MYO5A,TGIF1,MRS2,SYBU,MAML2,BSDC1,TXK,KLHL2,HLA-B,SYT7,AMMECR1,TBX18,PPM1H,GRAMD1C,ATP6V1C1 |
| 1.335e-02 | -4.32 | proteasome accessory complex | cellular component | GO:0022624 | 23 | 8 | 17570 | 2579 |
PSMD1,PSMD3,PSME2,PSMC2,PSMD7,PSMD10,PSME1,PSMC1 |
| 1.336e-02 | -4.32 | regulation of fatty acid oxidation | biological process | GO:0046320 | 27 | 9 | 16441 | 2455 |
IRS2,ACACB,PRKAG2,AKT1,PPARA,NR4A3,TWIST1,TYSND1,PLIN5 |
| 1.336e-02 | -4.32 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0045736 | 27 | 9 | 16441 | 2455 |
PLK1,TFAP4,CDK5RAP1,CASP3,PTEN,FBXO7,CDKN1B,HEXIM2,UBE2C |
| 1.336e-02 | -4.32 | lipid storage | biological process | GO:0019915 | 27 | 9 | 16441 | 2455 |
SOAT1,ENPP1,ACVR1C,PNPLA2,HEXB,DGAT2,GM2A,PLIN5,B4GALNT1 |
| 1.336e-02 | -4.32 | positive regulation of phosphatase activity | biological process | GO:0010922 | 27 | 9 | 16441 | 2455 |
CALM2,BMP2,PPP1R12A,NPNT,CALM1,PPP2R4,CALM3,SLC39A10,GPLD1 |
| 1.336e-02 | -4.32 | positive regulation of release of cytochrome c from mitochondria | biological process | GO:0090200 | 27 | 9 | 16441 | 2455 |
PPIF,PINK1,BMF,DNM1L,PLAUR,BIK,TP53,BAX,GPER1 |
| 1.337e-02 | -4.31 | cation binding | molecular function | GO:0043169 | 4106 | 655 | 16491 | 2452 |
DOC2A,ACACB,TRIM24,TRIM5,SLC25A13,RET,CACNA2D2,XIAP,LACTB2,SYTL4,CA8,BARD1,LTBP3,PHF1,ZNF275,EPDR1,TP73,CALM2,WEE1,ZYX,CABP1,CYP2S1,KLF3,ATP13A3,PPP1CA,WBP4,RNF26,TIPARP,CPE,APOBEC3G,ERAP2,NEK4,VPS11,RNF11,SPRTN,CDA,LOXL2,RNF19B,PNKD,CYP4F3,LCP1,PIAS3,ENPP1,PLCG1,TRIM47,LIMK1,ATP7B,MYLK,AGFG2,RNASEL,ANXA11,NUAK1,CYP2J2,ITGA6,MTL5,ZNRF3,HPCAL4,RABGGTA,MARCH8,GNS,DNPEP,ZCCHC17,WDFY1,MEGF8,PRICKLE4,ZIC5,NEK2,CADPS2,ZMYM1,MOXD1,DGKG,MYLIP,SALL4,SHARPIN,FHL2,PLS1,PCTP,GNA11,DCP2,CYB5A,TIMM8A,S100A5,DYSF,B4GAT1,DRP2,ZNF502,RPS6KA3,CSRP2,XDH,ADAMTS16,EGLN1,DMPK,RNF224,LFNG,GALNT12,RHBDL3,TESK2,MOCS1,REPS1,ZNF385B,RCN1,RNF220,CDH1,ENPP5,MYT1,RNF169,ENPP4,ERMP1,APOBEC3D,XRCC6BP1,TRIM7,ZNF618,EBF2,PDLIM3,TRABD2A,PDXK,GEN1,MAPK12,HSP90B1,MAN1A2,TRAF2,ZNF219,NUCB2,DTX3L,CAPN2,ZFX,ARSG,MGAT4A,FAM20B,ZFAND4,PLEKHF1,ADAM15,ZNF230,NPTXR,RAG1,S100A6,MOB4,ADAMTS2,NUDT8,PLSCR1,RAPGEF2,GRIN1,DBR1,BLVRA,NEURL1B,ABLIM2,GALNT3,PLOD2,ATXN7L3,NR1D2,ACVRL1,SYT7,ZFP30,NR4A3,ARFGAP3,ITGAV,FHL1,OSR1,CYBRD1,PHC1,TLL2,MYL9,UNKL,TRIM2,AGRN,CNOT8,MCCC1,LMCD1,PHOSPHO1,NENF,MGAT5B,CDIPT,HDAC6,PLS3,RPS6KA2,NPNT,ARL1,LMAN2L,MKRN3,DDHD2,PAPL,DDX59,S100A13,ZNF462,THRB,PCGF5,KCNIP3,MARK1,ING1,MCTP1,CELSR2,ESYT1,IDH1,ZBTB7B,RHEB,KDM4D,DZIP1L,TRIM9,PLCH1,KLF12,P4HA2,ZNF367,KLF11,POMT1,TC2N,MYL12B,PRKAA2,PARP12,LMTK3,ZCCHC24,RASA2,RACGAP1,B4GALT4,FBLN1,RSAD1,TIMP1,GATA2,FRAS1,PIM1,PLCB2,CYP26B1,CHSY3,PCDH1,TESK1,ZNF320,MGAT4B,ZSCAN12,ZDHHC3,G2E3,CDK5R1,RASGRP2,ZC2HC1A,FA2H,PHLPP2,ITGA7,PRPS2,P4HA3,ZDHHC7,LTBP2,ZDBF2,RNF146,UGP2,P3H2,CTDSPL,DGKA,TP53,ZNF28,RASGRP3,CYP26A1,SYTL2,SDF4,LMO4,LHX6,SRR,BCL6,ZDHHC23,CDH3,VAT1,NOTCH3,OAS3,LMAN1,EGLN3,CTDSP2,SULF2,CPD,SIRT1,TIMP2,FIGNL1,S100A4,ACO1,MYL12A,DAG1,ATP13A2,PTGS2,ZNF628,DUOX1,IDE,ATP1A1,MMP17,STK38,ADAMTS14,MAOA,ANXA9,ZBTB6,SYT13,AIFM3,LTA4H,ZNF701,ZC3HC1,CTDSP1,MAN2B2,ZMAT1,PINK1,DYRK3,CDH22,TAB3,SCD5,GNE,GNAL,MCTP2,ERI2,GTF3A,JAG2,NRP2,PPP2R3A,ZDHHC21,FOXP2,ALPP,TRIM21,HMGCL,KLF9,ATP2B1,FAH,P2RX4,FBLN5,NR3C1,AMFR,CRIP2,PPARA,PRICKLE1,TRIM35,CAPNS1,RNPEP,DGKE,DDAH1,FAT4,NEIL3,ZMYND19,ZNF214,PPP2R3C,PKD2,ZBTB33,ACVR1,HSPG2,ATP8A1,GATA3,PJA2,NCS1,PICK1,ASPHD2,HELZ2,CYP1A1,ZNF823,STIM1,PRICKLE3,ZFP36,POLL,STEAP2,AOX1,MARCH2,ZBTB18,SMYD5,METAP2,ACVR1C,PIF1,GALNT7,AURKB,MCFD2,ZFAND5,TP53I3,POR,PRIM1,GDE1,GNPTAB,PTER,NKD1,PRDM5,BMP1,DHTKD1,TRAF5,FGD1,DDX58,KLF2,CALB2,DGKQ,ADO,PRKAA1,NOTCH2,S100A2,PRRG4,MECOM,SH3RF2,CALR,ITGA3,ZNRF2,NECAB3,MSH2,CACNA1D,PIKFYVE,MAST4,SYTL3,ZNF117,RIMS2,PMPCB,ZNF84,MFI2,TBC1D8B,CALM1,DCHS1,PYGL,WHSC1,ATP8B3,PKM,KDM3A,JADE2,ANTXR1,PDE11A,DGKH,MMP15,NT5C2,PRKAG2,ZDHHC20,MATN2,ARAP1,PIAS2,AGBL5,FGD6,PCDH19,NR4A2,ZBTB34,MAP3K5,IFIH1,EHD1,PKD1L2,PLA2G4A,CAPN12,REPS2,S100A11,THRA,RPS6KA1,IQGAP1,SUZ12,ATP2C2,FTH1,RNF182,EGR3,NUDT12,DDR1,CYP39A1,ZFYVE9,APOBEC3B,APLP2,CYHR1,ZNF75D,ACAP2,RNASEH2A,PDE4D,NR2C1,SEC23A,CLSTN1,UTRN,COX11,PRKCQ,SLC11A2,ATP1B1,PKMYT1,PYGO1,CBL,ATP10D,SP4,ZNF469,NIN,ZMPSTE24,AMZ2,FYN,ZNF641,STK26,NGFRAP1,HAGHL,ZNF704,PPP1CB,EFCAB14,KLF5,ZC3H12B,B4GALT3,NR3C2,ATMIN,PLSCR4,ATP9A,EFHD2,CBLL1,APOBEC3H,CYB561,RNF128,PHF7,MGAT1,PPP1R10,PTEN,ATP8B1,ERCC2,MAP3K7,CNOT6L,GFI1,TRIM62,MSH6,SHMT1,ARHGEF28,ARAP2,LONRF3,PAPD7,ZC3H11A,FURIN,ZKSCAN2,AIF1L,ARSK,CDK5RAP1,NUCB1,TIMP3,PGM2L1,ERAP1,LRRK1,ARSB,MELK,ESYT2,USP16,NMRK1,LTBP1,DNER,TRIM68,HTR1D,CHPF,ADPRHL1,ZFYVE16,ZCCHC12,IMPAD1,SIVA1,ASH2L,NFU1,MYRIP,RASGRP1,SP5,CYP1B1,SOD1,CXXC5,TRIM8,ASXL1,LAP3,RNF165,TCN2,CXXC4,MAN2A2,NEIL1,ZNF114,TRIM45,ZNF165,SP6,ADIPOR1,CHPT1,CPPED1,CAPN1,NR2C2,LASP1,ARAP3,ZNF395,CALM3,TEC,PHLPP1,ZNF432,CA2,PFKL,FAM20C,EBF4,PRKCI,LIMCH1,ZNF692,ZRANB1,SNED1,GYLTL1B,PDE5A,RNF113A,NUBP1,STEAP1,AMDHD1,FECH,GNAS,NUDT16,CGREF1,PAPD5,YOD1,EGFL7,RARG,DRD1,KLF7,LMO7,SLC25A24,ZSWIM5,SOD2,GMPR,COL18A1,MORC4,ZMYND10,OSR2,MICALL2,EXT2,ZNF687,SETDB2,CYP4F11,ZDHHC12,ZBTB49,STEAP3,ECE1,APIP,ETHE1,LOXL1,CHP1,MAP3K3,GCA,ZNF525,RFK,GLO1,MAP3K6,JADE1,PEX2,OVOL1,CANT1,CYP2U1,GLIS3,FBLIM1,ANXA3,ENO2,CIT,SHPRH,LRP4,TGFBR1,ITGA2B,HDAC9,ZNF212,IRF2BPL,TOP2A,MLPH,TAF1B,GALNS,ZDHHC13,TRIM3,MYO5A,PHF20L1,PGM1,ADAM17,NR4A1,GCLC,RC3H2,OGDHL,MBNL3,ENDOD1,MARC1,SWAP70,TRIM69,FIBCD1,DTX4,TADA2B,CSGALNACT1,GEM,PLOD3,ZMIZ1,ZNF596 |
| 1.337e-02 | -4.31 | RGS | smart domains | SM00315 | 34 | 11 | 9131 | 1455 |
SNX13,RGS9,RGS12,ADRBK1,ARHGEF11,RGS3,RGS20,RGS5,GRK6,RGS14,ADRBK2 |
| 1.342e-02 | -4.31 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP | 171 | 36 | 17758 | 2588 |
FARP1,EPAS1,GATA3,RHPN2,PRSS22,SLC9A7,ABCD4,TGFBR3,MGAT1,RALB,REEP1,POLL,RAB27B,TMEM9,SYTL3,SCN3A,SNX8,DDB2,RIPK2,SLC39A8,STAT4,PLEKHO1,UBAC1,RNPEP,IRS2,CD8A,SWAP70,TBC1D17,HTT,DOLPP1,SPINT2,PLOD3,POMT1,CCDC97,NIPA1,FAM45A |
| 1.343e-02 | -4.31 | - | gene3d domains | 1.10.840.10 | 30 | 10 | 9988 | 1574 |
BCAR3,RASGRF1,RALGPS2,SH2D3C,RAPGEF2,KNDC1,RASGRP3,RASGEF1A,RASGRP1,RASGRP2 |
| 1.343e-02 | -4.31 | ZFP41 (ZFP41 zinc finger protein) | protein interactions | 286128 | 43 | 13 | 16036 | 2547 |
GRN,LTBP1,MPRIP,AGRN,PPP1R10,FRAS1,LRP4,SORL1,PYGL,GYS1,NOTCH2,NOTCH3,FBLN1 |
| 1.343e-02 | -4.31 | TSC1 (tuberous sclerosis 1) | protein interactions | 7248 | 43 | 13 | 16036 | 2547 |
PLK1,TSC1,NF2,AKT1,NGFRAP1,RPS6KA1,DAPK1,EZR,CDKN1B,CCNB1,CDK1,RHEB,FBXW5 |
| 1.347e-02 | -4.31 | GSE31082_DN_VS_DP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_DP_THYMOCYTE_DN | 194 | 40 | 17758 | 2588 |
OTUD5,LZTFL1,ANKRD13D,TAOK2,TNRC6C,DNAJC3,CCM2,AES,LYNX1,CAMK1D,MAP1LC3B,PHF1,NFAT5,LBR,KIF5B,APLP2,SIPA1L2,ZNF687,FRYL,TNPO2,SGK1,CNGA1,DLG3,MAPK7,TRAM1,S100A13,CTDSP2,PHKG2,SMC4,TRAK2,ORAI2,ARAP2,ARHGDIB,BCL10,TRIOBP,NETO2,NFKBIZ,ACADM,TOB1,FBXW5 |
| 1.347e-02 | -4.31 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 194 | 40 | 17758 | 2588 |
GAA,AASS,DAP,DNAJB2,PPFIBP2,TAP1,GDF15,TP53I11,SRPX2,H1FX,SAC3D1,SH3BP1,PLCG2,AKR1B1,CNPY3,ALDH3A2,RIMS2,SNED1,EPHX1,MX1,SOD1,TIMP2,PSMB4,IFITM3,CAPNS1,FXR2,FUCA1,RPL12,RBL1,STAT6,SECTM1,NMI,RHOBTB2,CTSA,KPNA2,IRF7,PLXND1,MAFF,IRF1,EHD1 |
| 1.349e-02 | -4.31 | regulation of organ morphogenesis | biological process | GO:2000027 | 156 | 34 | 16441 | 2455 |
CTHRC1,RUNX2,HOXB7,LGR4,SOX9,ETV5,GATA3,ZNRF3,FZD6,SIX4,BMP2,PDGFA,CTNNB1,BMP7,SMO,BAX,TFAP2A,TACSTD2,NTN4,TWIST1,CITED2,WNT3A,ETV4,DVL2,HES1,NFIB,POR,FGFR2,CSF1,TBX1,PTK7,STAT1,SP6,SOX8 |
| 1.349e-02 | -4.31 | COATES_MACROPHAGE_M1_VS_M2_DN | MSigDB lists | COATES_MACROPHAGE_M1_VS_M2_DN | 72 | 18 | 17758 | 2588 |
SOAT1,FBLIM1,LASP1,PINK1,FAM199X,MCOLN3,EFHD2,GDF15,FAM198B,MGST2,AKR1E2,ARSK,PDXDC1,HS6ST1,GPRC5B,EGLN3,ATG4D,XDH |
| 1.349e-02 | -4.31 | DITTMER_PTHLH_TARGETS_DN | MSigDB lists | DITTMER_PTHLH_TARGETS_DN | 72 | 18 | 17758 | 2588 |
PSMB4,TBC1D1,RAPGEF2,ITGA6,PIK3R1,SPTLC2,LMNA,SNX13,FBXO7,PIK3CA,AOX1,ZDHHC7,ALDH7A1,ARPC2,MAP3K7,SEMA3A,HSPA2,FAH |
| 1.349e-02 | -4.31 | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | MSigDB lists | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | 72 | 18 | 17758 | 2588 |
COL9A3,ACACB,CAPN6,RET,COL4A5,ISYNA1,KBTBD11,NFIB,ALDH5A1,LRRN2,FGFR2,FGF18,TLE1,IGFBP2,EPB41L4B,APBA2,ITM2C,MDFI |
| 1.350e-02 | -4.31 | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | 37 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,SMO,PIK3CA,IDH1,GNA11,EGFR |
| 1.350e-02 | -4.31 | salivary_gland-orbital-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-orbital-carcinoma-adenoid_cystic_carcinoma | 37 | 11 | 17775 | 2585 |
DIRAS3,TSC1,RUNX2,FGFR2,MAP3K9,NOTCH2,SEPP1,CLCN2,ESPL1,ALDH3A2,ABCA1 |
| 1.350e-02 | -4.31 | orbital | COSMIC cancer mutations | orbital | 37 | 11 | 17775 | 2585 |
DIRAS3,TSC1,RUNX2,FGFR2,MAP3K9,NOTCH2,SEPP1,CLCN2,ESPL1,ALDH3A2,ABCA1 |
| 1.351e-02 | -4.30 | G alpha (12/13) signalling events | REACTOME pathways | R-HSA-416482 | 75 | 19 | 8202 | 1235 |
ARHGEF3,RHOA,ARHGEF11,ARHGEF7,PIK3R1,GNB2,RHOB,ARHGEF16,ABR,RAC2,GNB5,MCF2L,PIK3CA,ARHGAP4,TIAM1,ARHGEF9,NGEF,FGD1,ARHGEF4 |
| 1.356e-02 | -4.30 | KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | MSigDB lists | KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | 115 | 26 | 17758 | 2588 |
PLA2G4A,MYL9,RHOA,PPP1R12A,ARHGEF11,CALM1,CALCRL,CALM3,PRKCQ,ITPR2,ITPR3,PRKACA,GNA11,EDNRA,GNAS,CALM2,KCNMB4,CALD1,ITPR1,MYLK,PRKG1,PPP1CB,ACTA2,CACNA1D,PPP1CA,PLCB2 |
| 1.363e-02 | -4.30 | endoplasmic reticulum-Golgi intermediate compartment | cellular component | GO:0005793 | 98 | 23 | 17570 | 2579 |
RGMB,ERP44,CTSZ,COL7A1,MCFD2,NUCB2,BCAP31,STK17B,NUCB1,PROM1,SERPINA1,CTSC,P4HB,AREG,DDHD2,PIEZO1,MYDGF,LMAN1,PDIA6,TMED2,GOLGB1,CHP1,KDELR1 |
| 1.363e-02 | -4.30 | IRE1alpha activates chaperones | REACTOME pathways | R-HSA-381070 | 55 | 15 | 8202 | 1235 |
GFPT1,SEC61B,ADD1,WIPI1,SEC61G,WFS1,DNAJC3,PDIA5,DNAJB11,KDELR3,MYDGF,PDIA6,CTDSP2,DNAJB9,LMNA |
| 1.363e-02 | -4.30 | Arachidonic acid metabolism | REACTOME pathways | R-HSA-2142753 | 55 | 15 | 8202 | 1235 |
MAPKAPK2,PLA2G4A,FAM213B,PTGS2,CYP1A1,CYP4F11,FAAH,CYP2J2,CYP2U1,LTA4H,PTGES,CYP4F3,ABCC1,CYP1B1,GPX4 |
| 1.365e-02 | -4.29 | - | gene3d domains | 3.30.505.10 | 112 | 27 | 9988 | 1574 |
INPPL1,INPP5D,STAT4,PIK3R1,TNS1,TEC,YES1,CBL,RASA1,SH2D4A,SOCS3,TXK,BCAR3,TNS4,PLCG1,TNS3,FYN,JAK1,SHC3,STAT6,SH2D3C,RIN3,PLCG2,STAT1,JAK3,SYK,SOCS5 |
| 1.369e-02 | -4.29 | EP300 (E1A binding protein p300) | protein interactions | 2033 | 477 | 94 | 16036 | 2547 |
GAA,PAX6,HOXB7,EPAS1,THRA,TP53,CCNB1,HDAC6,RAD23A,TP73,CCND1,SS18,PCNA,CCNA2,CTNNB1,CDH1,TACC2,MITF,FOSB,BCL6,IRF2,TWIST1,ZBTB49,ASH2L,TINAGL1,CTTN,ETV4,SIRT1,SMARCA2,ING1,CITED4,AKT1,CDC20,AURKB,SAV1,ZBTB7B,CDK1,PDHX,PIAS3,PTGS2,STAT6,STAT1,HDAC1,KLF5,KPNA2,IRF7,KLF11,ARNT,KLF2,RUNX2,TRAF2,SOX9,PRKAA1,TGFBR1,SEPP1,ETS1,HOXB2,ELF3,RB1,FLII,TAF1B,NOXA1,GATA2,PAK2,TFAP2A,ACTA2,BRD7,CITED2,NCOA2,MSH6,DDB2,PLSCR1,NR3C1,NR4A1,PIK3R1,PPARA,MYBL2,FHL2,RUNX3,MAML2,PKM,ELK1,FOS,CRTC2,NCOA3,ETS2,E2F1,FHL1,MAP3K5,USF2,AHR,CTBP1,ZBTB33,IRF1 |
| 1.370e-02 | -4.29 | IDENTICAL_PROTEIN_BINDING | MSigDB lists | IDENTICAL_PROTEIN_BINDING | 300 | 58 | 17758 | 2588 |
S100A11,TRIP10,HEXB,ABCG4,ABCG2,ERBB2,BCL2L1,GPSM2,BARD1,ITGA2B,SLC9A7,DAPK2,TOP2A,FOXP2,E2F7,CARD8,IGF1R,PAK2,CST3,PASK,MSH2,MAP3K9,BAX,CLDN4,ABCD1,OSTF1,APIP,ALS2CL,DVL2,S100A6,CCDC88A,MSH6,AKT1,RGMB,CDA,BNIP3L,CR2,EIF2AK1,SAV1,PSMA4,EGFR,FAS,GNAS,FYN,PVRL2,TBX1,NFKBIA,PPP2R4,KIAA1804,MAP3K11,HDAC1,ANXA9,GLA,MAP3K5,USF2,NRBP1,DMPK,ABCG1 |
| 1.370e-02 | -4.29 | PX | smart domains | SM00312 | 43 | 13 | 9131 | 1455 |
SNX8,SNX13,SNX18,SGK3,SNX16,PLD2,PIK3C2B,PLD1,SNX9,SNX10,SNX12,SNX30,SNX7 |
| 1.370e-02 | -4.29 | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN | MSigDB lists | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN | 37 | 11 | 17758 | 2588 |
KIF5B,CDK5RAP1,ACAD10,CASP9,SLC44A1,POMT1,CITED2,PCTP,CPEB2,PDXDC1,WBP5 |
| 1.370e-02 | -4.29 | CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | MSigDB lists | CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 37 | 11 | 17758 | 2588 |
CASP3,CAPN6,CTSB,CASP9,PDIA3,USP1,CAPNS1,LGMN,USP16,ATG4D,USP6 |
| 1.374e-02 | -4.29 | protein modification by small protein conjugation | biological process | GO:0032446 | 726 | 130 | 16441 | 2455 |
CCNC,UNKL,TRIM2,TRIM24,TRIM5,CUL4B,XIAP,FBXO2,CUL1,UBE2Z,UBE2Q1,PSME1,HDAC6,PJA2,BARD1,SPSB1,TRIM68,PSMD1,NUP210,UBE2T,MKRN3,PSMC2,MARCH2,PLK1,TRIM8,FBXL16,ITCH,RNF11,RNF165,CCNF,RNF19B,VCP,PIAS3,TRIM9,TRAF5,PSMC1,ASB9,PSMD7,ZNRF3,HERC6,SH3RF2,MARCH8,UBE2Q2,ZNRF2,FBXO7,FBXL14,MYLIP,NUP85,PSMA5,SOCS5,DDB2,SHARPIN,KBTBD8,PSMA4,FBXO10,G2E3,PELI2,KBTBD2,PIAS2,DCUN1D1,IFIH1,NUP58,RNF146,RUSC1,RAD21,FBXW5,LMO7,PAX6,PSME2,SUZ12,WDTC1,RNF182,KBTBD11,RNF220,SP100,RNF169,SIRT1,TCEB2,AKT1,CDC20,PRKCQ,ASB13,CBL,SOCS3,PSMD3,WWTR1,PEX2,AREL1,CBX4,ZC3HC1,PINK1,KLHL13,TRAF2,DCAF7,SHPRH,CDCA3,HERC5,PSMD10,CBLL1,FBXO6,TSPAN17,WWP2,DTX3L,RNF128,IRAK1,UBE2J1,TRIM3,TRIM21,WWP1,RAG1,TRIM62,DCAF6,PSMB4,AMFR,NUB1,RC3H2,UBE2A,FBXO9,UBAC1,PELI3,NEURL1B,DCAF10,KLHL2,TRIM69,DTX4,UBE2D2,ARRB1,NUP37,UBE2C,PHC1 |
| 1.376e-02 | -4.29 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | 177 | 37 | 17758 | 2588 |
ACVR1,DYRK3,LGALS3,GNPDA1,UBASH3B,S100A2,SNX9,SPP1,WDFY1,EFR3A,ADCK2,SGK1,BRI3,PTPRE,SPRY2,WBP5,SNX8,LONRF3,MFI2,LHFPL2,C18orf8,RHOB,STX3,BCAR3,ANKRD10,SLCO4A1,SCARB2,SERTAD2,PRKAG2,PPP2R5A,CORO1C,CSF1,NR4A2,GEM,WDR91,ZC3HC1,RRAGD |
| 1.377e-02 | -4.28 | CD2AP (CD2-associated protein) | protein interactions | 23607 | 91 | 23 | 16036 | 2547 |
UFD1L,NR3C1,NR4A1,INPP5D,PIK3R1,YES1,CBL,BCAR1,EGFR,SH3KBP1,LMNA,ZYX,FYN,RABEP2,CCDC6,SH3BP1,DNM2,CSTF2,PKD2,CTTN,NRBP1,NR2C2,FRS3 |
| 1.377e-02 | -4.28 | SYNE4 (spectrin repeat containing, nuclear envelope family member 4) | protein interactions | 163183 | 91 | 23 | 16036 | 2547 |
B3GALT6,GOLIM4,TSPAN15,TMTC3,C3orf52,KLC2,DSE,TMPRSS4,KTN1,FZD6,KIF5B,LEMD2,OSTCP1,TRIM69,PAQR5,FAM20B,TMEM248,KLC3,SARAF,MARCH2,POMT1,SMCO4,OCLN |
| 1.377e-02 | -4.28 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | 88 | 21 | 17758 | 2588 |
KLF2,SPEF2,ERLEC1,MACC1,TACC1,PLEKHA7,FBXO2,RASGRP3,RACGAP1,LCP1,PARM1,AHRR,ENDOD1,SCARB2,FAM46A,TSPAN13,EFNA5,NTN4,FAM84B,NPTXR,CPEB2 |
| 1.377e-02 | -4.28 | WINTER_HYPOXIA_UP | MSigDB lists | WINTER_HYPOXIA_UP | 88 | 21 | 17758 | 2588 |
PLEKHG3,TUBB4B,TMTC3,NDRG1,AK4,TFAP2C,PYGL,VEZT,COL4A5,HES2,ANLN,PTGFRN,BCAR1,PGF,TNS4,C16orf74,CDCA4,CORO1C,PPP4R1,TANC2,ANKRD9 |
| 1.378e-02 | -4.28 | PRKCD (protein kinase C, delta) | protein interactions | 5580 | 142 | 33 | 16036 | 2547 |
RUNX2,ADD1,IBTK,INPP5D,ITGA6,HABP4,SDC4,TP53,RASGRP3,PLD2,GRM5,IGF1R,IRAK1,ADRBK1,IL6ST,PIK3CA,ACTA2,PPP1CA,TIAM1,MBP,PLSCR1,PPARA,PRKCQ,RANBP9,VCP,EGFR,INSR,FYN,ITPR1,STAT1,KLF5,HSPB1,AFAP1 |
| 1.378e-02 | -4.28 | JNK cascade | biological process | GO:0007254 | 86 | 21 | 16441 | 2455 |
RIPK2,TAB3,PTGER4,PKN1,TNFRSF19,MAP3K6,MAPK8IP1,IRAK1,SH2D3C,NOD2,MAP3K9,MAP3K11,KIAA1804,DUSP10,MDFIC,DAB2IP,MAP3K7,MAP3K5,GAB1,SYK,MDFI |
| 1.379e-02 | -4.28 | - | gene3d domains | 3.90.370.10 | 4 | 3 | 9988 | 1574 |
TIMP3,TIMP2,TIMP1 |
| 1.379e-02 | -4.28 | - | gene3d domains | 3.40.225.10 | 4 | 3 | 9988 | 1574 |
APIP,ADD3,ADD1 |
| 1.382e-02 | -4.28 | skin-face-other-keratoacanthoma | COSMIC cancer mutations | skin-face-other-keratoacanthoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | spindle_and_epithelioid | COSMIC cancer mutations | spindle_and_epithelioid | 19 | 7 | 17775 | 2585 |
RB1,CDH1,CTNNB1,AKT1,PTEN,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | skin-scalp-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-scalp-malignant_melanoma-superficial_spreading | 19 | 7 | 17775 | 2585 |
ERBB2,AKT1,FLT3,FGFR2,EGFR,RET,PIK3CA |
| 1.382e-02 | -4.28 | skin-lower_leg-other-keratoacanthoma | COSMIC cancer mutations | skin-lower_leg-other-keratoacanthoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | genital | COSMIC cancer mutations | genital | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | skin-upper_arm-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-upper_arm-carcinoma-squamous_cell_carcinoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | skin-chest-other-keratoacanthoma | COSMIC cancer mutations | skin-chest-other-keratoacanthoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | skin-genital-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-genital-carcinoma-squamous_cell_carcinoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | soft_tissue-fat-liposarcoma-dedifferentiated | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-dedifferentiated | 19 | 7 | 17775 | 2585 |
RB1,CTNNB1,CDH1,IDH1,PTEN,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | skin-arm-other-keratoacanthoma | COSMIC cancer mutations | skin-arm-other-keratoacanthoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | ependymoma_Grade_II | COSMIC cancer mutations | ependymoma_Grade_II | 19 | 7 | 17775 | 2585 |
TSC1,RB1,NF2,CTNNB1,AKT1,IDH1,PTEN |
| 1.382e-02 | -4.28 | skin-back-other-keratoacanthoma | COSMIC cancer mutations | skin-back-other-keratoacanthoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | skin-sole-malignant_melanoma-nodular | COSMIC cancer mutations | skin-sole-malignant_melanoma-nodular | 19 | 7 | 17775 | 2585 |
ERBB2,AKT1,FLT3,FGFR2,EGFR,RET,PIK3CA |
| 1.382e-02 | -4.28 | skin-upper_leg-other-keratoacanthoma | COSMIC cancer mutations | skin-upper_leg-other-keratoacanthoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle_and_epithelioid | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle_and_epithelioid | 19 | 7 | 17775 | 2585 |
RB1,CTNNB1,CDH1,AKT1,PTEN,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | skin-leg-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-leg-carcinoma-squamous_cell_carcinoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | skin-lip-other-keratoacanthoma | COSMIC cancer mutations | skin-lip-other-keratoacanthoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | breast-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | breast-carcinoma-adenoid_cystic_carcinoma | 19 | 7 | 17775 | 2585 |
ERBB2,AKT1,FLT3,PTEN,EGFR,RET,PIK3CA |
| 1.382e-02 | -4.28 | skin-chest-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-chest-carcinoma-squamous_cell_carcinoma | 19 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.382e-02 | -4.28 | soft_tissue-fibrous_tissue_and_uncertain_origin-solitary_fibrous_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-solitary_fibrous_tumour | 19 | 7 | 17775 | 2585 |
ERBB2,SS18,CTNNB1,IDH1,EGFR,NAB2,TP53 |
| 1.383e-02 | -4.28 | response to metal ion | biological process | GO:0010038 | 299 | 59 | 16441 | 2455 |
SCN5A,CASP3,SLC25A24,SLC25A13,NDRG1,IQGAP1,MTL5,CALM3,P2RX7,CCNB1,SDC1,ICAM1,CALM2,CCND1,CALR,CPNE2,CYP1A1,PCNA,CDH1,CA2,STIM1,PTEN,FOSB,SLC30A6,BAX,TFAP2A,TRPC1,CDKN1B,IGFBP2,S100A13,DUSP1,PPIF,SOD1,DMTN,CALM1,CASP9,GRIN1,ACO1,SLC11A2,GGH,LOXL2,ITPR3,FOS,CYB5A,FAS,RASGRP2,GPLD1,ATP13A2,FECH,PTGS2,KCNMB4,HTT,ATP7B,ALG2,TRPC3,LTA4H,PTGES,CYBRD1,ANXA11 |
| 1.388e-02 | -4.28 | GEORGANTAS_HSC_MARKERS | MSigDB lists | GEORGANTAS_HSC_MARKERS | 67 | 17 | 17758 | 2588 |
KLF2,TRIM8,HLA-E,RAPGEF2,GATA3,FAM198B,MECOM,PLS3,HLF,H1F0,IL6ST,FOSB,INPP4B,LIMCH1,TIPARP,HSPB1,CYBRD1 |
| 1.388e-02 | -4.28 | GNF2_RAD23A | MSigDB lists | GNF2_RAD23A | 67 | 17 | 17758 | 2588 |
TMCC2,ERMAP,MPP1,BLVRB,BNIP3L,FBXO9,UBAC1,EIF2AK1,SPTB,RAD23A,FECH,MARCH8,ANK1,CA2,H1F0,FBXO7,TRAK2 |
| 1.388e-02 | -4.28 | KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | MSigDB lists | KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | 67 | 17 | 17758 | 2588 |
PRKAA2,ACACB,SLC2A4,NFKBIE,AKT1,TRAF2,CAMKK1,PRKAA1,PPARA,PRKCQ,LEPR,SOCS3,IRS2,PRKAG2,NFKBIA,ADIPOR1,ACSL4 |
| 1.388e-02 | -4.28 | ENDOSOME | MSigDB lists | ENDOSOME | 67 | 17 | 17758 | 2588 |
LAMP2,LAMP1,NF2,IL15,BACE1,VPS4B,DNER,EGFR,LDLRAP1,WDFY1,FYN,TM9SF2,CTNS,ATP7B,STEAP2,ARF6,PLIN3 |
| 1.388e-02 | -4.28 | GNF2_BNIP3L | MSigDB lists | GNF2_BNIP3L | 67 | 17 | 17758 | 2588 |
TMCC2,ERMAP,GCLC,MPP1,BLVRB,BNIP3L,FBXO9,EIF2AK1,SPTB,RAD23A,FECH,MARCH8,ANK1,CA2,H1F0,FBXO7,TRAK2 |
| 1.389e-02 | -4.28 | PLC-gamma1 signalling | REACTOME pathways | R-HSA-167021 | 36 | 11 | 8202 | 1235 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PRKAR1A |
| 1.391e-02 | -4.28 | immune effector process | biological process | GO:0002252 | 459 | 86 | 16441 | 2455 |
UNC93B1,TRIM5,TUBB4B,LFNG,INPP5D,DNAJC3,TP53,GATA3,ITPR2,EMP2,ELMOD2,APOBEC3B,CD46,ELMO2,PLCG2,PIK3CA,DLG1,IFIT1,PIK3CD,OAS3,IL10RB,S100A13,APOBEC3G,RASGRP1,MX1,CD55,APOBEC3D,LGALS8,ITCH,BNIP3L,PTGER4,CR2,CD40,ITPR3,RNF19B,LCP1,PLCG1,FYN,LIMK1,STAT6,NOD2,STAT1,IRF7,RNASEL,F2RL1,DDX58,ANXA3,SERPINB9,HERC5,PLD2,APOBEC3H,NCKAP1,NOTCH2,IL18R1,ICAM1,FAM111A,CTSC,GATA2,MSH2,ULBP2,SYK,MSH6,ADAM17,PLSCR1,IFITM3,MICB,PIK3R1,RC3H2,RGCC,BTN3A2,YES1,IFIT3,CYFIP2,FAS,BCL10,CD8A,TSC1,SWAP70,ITPR1,RAET1L,NR4A3,NLRC5,ARPC2,IFIH1,TMEM173,IRF1 |
| 1.391e-02 | -4.27 | skeletal system development | biological process | GO:0001501 | 471 | 88 | 16441 | 2455 |
PAPSS2,GRHL2,HSPG2,HOXB7,THRA,HEXB,P2RX7,PHOSPHO1,OSR2,FAM101B,PLS3,PDGFA,NOV,CTNNB1,CTGF,IMPAD1,PAPSS1,DLG1,TWIST1,TIPARP,SP5,SULF2,SPEF2,ASXL1,PTGER4,PRKRA,ZFAND5,COL12A1,TBX1,HOXA9,TRIM45,BMP1,PCSK5,INPPL1,RUNX2,CDKN1C,LGALS3,HAPLN3,SOX9,RAB23,TGFBR1,JAG2,DHRS3,HOXB2,SIX4,SGPL1,BMP2,TIMP1,ITGB8,CYR61,FAM20C,BMP7,MEGF8,TFAP2A,USP1,MDFI,CYP26B1,UFD1L,PDGFC,RHOA,WNT10B,FMN1,ANO6,DCHS1,AMER1,WHSC1,RUNX3,FAM73B,BBS2,GNA11,NFIB,GPLD1,PITX2,GNAS,FAT4,ETS2,FGFR2,COL13A1,SEMA4D,NAB2,FGF18,CSGALNACT1,LRRK1,GDF11,OSR1,SHOX2,RARG,RPS6KA3 |
| 1.392e-02 | -4.27 | - | gene3d domains | 2.10.110.10 | 72 | 19 | 9988 | 1574 |
LMO7,FBLIM1,LASP1,CRIP2,LMCD1,FHL2,PRICKLE1,MICALL2,ABLIM2,ZYX,PDLIM3,LIMK1,PRICKLE4,LMO4,PRICKLE3,LHX6,LIMCH1,FHL1,CSRP2 |
| 1.393e-02 | -4.27 | pancreas-carcinoid-endocrine_tumour-non_functioning | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-non_functioning | 11 | 5 | 17775 | 2585 |
CDKN2C,RB1,CTNNB1,PTEN,TP53 |
| 1.393e-02 | -4.27 | central_nervous_system-supratentorial-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-supratentorial-primitive_neuroectodermal_tumour-medulloblastoma | 11 | 5 | 17775 | 2585 |
CTNNB1,IDH1,PTEN,SMO,TP53 |
| 1.393e-02 | -4.27 | sarcomatoid_carcinoma | COSMIC cancer mutations | sarcomatoid_carcinoma | 11 | 5 | 17775 | 2585 |
ERBB2,CTNNB1,EGFR,PIK3CA,TP53 |
| 1.393e-02 | -4.27 | lung-carcinoma-signet_ring_cell_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-signet_ring_cell_adenocarcinoma | 11 | 5 | 17775 | 2585 |
KIF5B,ERBB2,AKT1,EGFR,PIK3CA |
| 1.393e-02 | -4.27 | gastrointestinal_tract_(site_indeterminate)-carcinoid-endocrine_tumour | COSMIC cancer mutations | gastrointestinal_tract_(site_indeterminate)-carcinoid-endocrine_tumour | 11 | 5 | 17775 | 2585 |
GNAS,CTNNB1,EGFR,RET,PIK3CA |
| 1.393e-02 | -4.27 | signet_ring_cell_adenocarcinoma | COSMIC cancer mutations | signet_ring_cell_adenocarcinoma | 11 | 5 | 17775 | 2585 |
KIF5B,ERBB2,AKT1,EGFR,PIK3CA |
| 1.393e-02 | -4.27 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_IV | 11 | 5 | 17775 | 2585 |
IDH1,MSH6,MSH2,PIK3CA,TP53 |
| 1.393e-02 | -4.27 | frontoparietal | COSMIC cancer mutations | frontoparietal | 11 | 5 | 17775 | 2585 |
CDKN2C,CTNNB1,IDH1,EGFR,TP53 |
| 1.394e-02 | -4.27 | regulation of adaptive immune response | biological process | GO:0002819 | 118 | 27 | 16441 | 2455 |
SIRT1,RIPK2,HLA-E,TRAF2,WHSC1,P2RX7,IL27RA,PRKCQ,PKN1,CD40,HLA-A,HLA-B,PVRL2,IL6ST,STAT6,BCL6,NOD2,DUSP10,IRF7,C10orf54,FZD5,MAP3K7,NDFIP1,JAK3,MSH6,SOCS5,IRF1 |
| 1.395e-02 | -4.27 | RhoGAP | pfam domains | PF00620 | 65 | 17 | 16629 | 2504 |
ARHGAP11A,ARAP3,ARAP2,RALBP1,PIK3R1,RACGAP1,ABR,SYDE2,ARHGAP35,ARHGAP24,ARHGAP42,SH3BP1,OCRL,FAM13B,ARAP1,ARHGAP4,STARD13 |
| 1.397e-02 | -4.27 | positive regulation of nitrogen compound metabolic process | biological process | GO:0051173 | 1781 | 298 | 16441 | 2455 |
ACVR1,TRIM24,LGR4,TRIM5,DNAJC3,HEXB,RET,GATA3,MORF4L2,CAMK1D,CCNB1,TP73,NPM2,CALM2,HELZ2,ZFP36,IL31RA,FOSB,DNM2,IRF2,NEK4,SMARCA2,TNIP1,TFAP2C,AURKB,LDB2,SAV1,ARF4,AHRR,AREG,TBX1,NOD2,HDAC1,RNASEL,TRAF5,F2RL1,E2F8,HOXC13,DDX58,KLF2,CDKN1C,ITGA6,SOX9,PRKAA1,PSIP1,LMNA,MECOM,ELF3,TFAP4,CALR,CYR61,NEK2,MYDGF,MAPK7,NUP85,GPR161,SALL4,STAT4,CALM1,PYM1,FHL2,MYBL2,WHSC1,CALCRL,ELK1,ILK,TP53INP2,KDM3A,NFIB,NCOA3,SERTAD2,ETS2,SETD3,PIAS2,NR4A2,RPS6KA3,TMEM173,IRF1,ARMCX3,GRHL2,THRA,RPS6KA1,CCNA2,CDH1,SP100,DAB2IP,ETV4,MED30,PSRC1,RIPK2,FZD4,FOXJ2,PRKCQ,PYGO1,GTF2A2,EBF2,FZD7,NFIX,WFS1,WWTR1,STAT1,KLF5,NRG1,ARNT,ATMIN,NKX3-1,TNRC6C,CKAP2,TRAF2,PBX3,ETS1,NFAT5,TEAD3,ICAM1,SIX4,WWP2,E2F7,IRAK1,PTEN,MCF2L,CST3,BAX,ERCC2,CITED2,MAP3K7,TRIM62,NCOA2,MSH6,PDGFC,CASK,PLSCR1,BCL9,TEF,PIK3R1,EIF5A2,GRIN1,YES1,FOS,ABLIM2,TXK,CRTC2,PITX2,FGFR2,ATXN7L3,PRDX3,NR1D2,ACVRL1,NR4A3,GPER1,HMGA1,FZD5,OSR1,CD81,USF2,SHOX2,FOXA1,USP16,RGMA,CCNC,EPAS1,AGRN,CNOT8,PDGFB,TFAP2E,EPCAM,HSF2,PCNA,CTNNB1,GRHL1,NPNT,PSMC2,ELF5,PASK,MITF,ASH2L,ARNT2,MYBL1,ZNF462,THRB,PCGF5,TRIM8,CITED4,ASXL1,NFE2L1,EAF2,VCP,EDNRA,KDM4D,SEC14L2,MDK,KLF12,MAFF,PSMC1,NR2C2,PRKAA2,RUNX2,PPP1R12A,ETV5,CALM3,BMP2,RB1,DAZAP1,IGF1R,GATA2,PRKCI,EBF4,MDFIC,WNT3A,ELK3,RGMB,EGFR,GNAS,ONECUT1,NUDT16,INSR,PLPP3,NFKBIA,NLRC5,RARG,TOB1,RAD21,DRD1,KLF7,PAX6,UPF3B,FOXM1,TP53,ERBB2,P2RX7,CCNL1,OSR2,LPIN3,PDGFA,SS18,LMO4,SMO,TWIST1,ZBTB49,NOTCH3,NFKB2,F2R,DVL2,UPF3A,CTH,SIRT1,TIMP2,AKT1,TCEB2,SERTAD3,CD40,JADE1,HSF4,PTGS2,RBL1,STAT6,IRF7,AKNA,ABCA1,GLIS3,ANXA3,PINK1,TAB3,ARHGEF11,GNAL,HMGN3,TGFBR1,PARM1,GBX2,IRF2BPL,TOP2A,BMP7,TOX2,GTF2F2,TFAP2A,BRD7,TRIM21,NFE2L3,P2RX4,HES1,RHOA,DCAF6,WNT10B,HMGN5,NR3C1,NR4A1,RGCC,PPARA,MAML2,RUNX3,MPV17L2,BCL10,DDAH1,E2F1,ARRB1,PKD2,ZMIZ1,SOX8,AHR |
| 1.398e-02 | -4.27 | WEST_ADRENOCORTICAL_CARCINOMA_VS_ADENOMA_UP | MSigDB lists | WEST_ADRENOCORTICAL_CARCINOMA_VS_ADENOMA_UP | 19 | 7 | 17758 | 2588 |
SAP130,SLC35C1,HOXB13,LONRF3,TCEB2,CDK16,CD22 |
| 1.398e-02 | -4.27 | INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY | MSigDB lists | INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY | 19 | 7 | 17758 | 2588 |
PDIA3,ERP44,PDIA6,GNPDA1,ERP29,P4HB,PDIA5 |
| 1.398e-02 | -4.27 | MODULE_320 | MSigDB lists | MODULE_320 | 19 | 7 | 17758 | 2588 |
KIF23,CENPE,KIF11,ESPL1,PTTG1,NDC80,RAD21 |
| 1.398e-02 | -4.27 | INSULIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | INSULIN_RECEPTOR_SIGNALING_PATHWAY | 19 | 7 | 17758 | 2588 |
SORBS1,INSR,IGF1R,AKT1,BCAR1,GAB1,PIK3R1 |
| 1.398e-02 | -4.27 | LI_WILMS_TUMOR_ANAPLASTIC_UP | MSigDB lists | LI_WILMS_TUMOR_ANAPLASTIC_UP | 19 | 7 | 17758 | 2588 |
NUSAP1,KPNA2,KIF2C,CENPA,HTT,CDK1,CDCA3 |
| 1.398e-02 | -4.27 | SESTO_RESPONSE_TO_UV_C3 | MSigDB lists | SESTO_RESPONSE_TO_UV_C3 | 19 | 7 | 17758 | 2588 |
TAX1BP3,PTGS2,RND3,MAD2L1BP,SOX9,DUSP1,IER3 |
| 1.398e-02 | -4.27 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | MSigDB lists | REACTOME_ENOS_ACTIVATION_AND_REGULATION | 19 | 7 | 17758 | 2588 |
CALM2,CALM3,AKT1,SPR,CALM1,ZDHHC21,DNM2 |
| 1.398e-02 | -4.27 | chr7p12 | MSigDB lists | chr7p12 | 19 | 7 | 17758 | 2588 |
SUN3,TNS3,FIGNL1,SEMA3A,COBL,EGFR,STK17A |
| 1.400e-02 | -4.27 | E1-E2_ATPase | pfam domains | PF00122 | 36 | 11 | 16629 | 2504 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP13A3,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 1.401e-02 | -4.27 | DARPP-32 events | REACTOME pathways | R-HSA-180024 | 27 | 9 | 8202 | 1235 |
CALM2,CALM1,CALM3,PRKAR2B,PPP1CA,PDE4D,PRKACA,PPP2R5D,PRKAR1A |
| 1.402e-02 | -4.27 | soft_tissue-smooth_muscle-leiomyosarcoma | COSMIC cancer mutations | soft_tissue-smooth_muscle-leiomyosarcoma | 42 | 12 | 17775 | 2585 |
CDKN2C,RB1,SS18,CTNNB1,CDH1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 1.402e-02 | -4.27 | leiomyosarcoma | COSMIC cancer mutations | leiomyosarcoma | 42 | 12 | 17775 | 2585 |
CDKN2C,RB1,SS18,CTNNB1,CDH1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 1.402e-02 | -4.27 | YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta) | protein interactions | 7534 | 337 | 69 | 16036 | 2547 |
TNK1,SSH1,KLC2,TP53,CUL1,BARD1,WEE1,CTNNB1,RGS3,TUBG1,CDKN1B,MAP3K3,SSH3,ING1,MARK1,AKT1,PFKFB2,DMTN,KIF1C,ERP44,TNS1,SAV1,CBL,CDC25C,VCP,GINS4,OPTN,IRS2,LIMK1,STK38,MADD,WWTR1,KLF11,HSPB1,ISOC1,CBX4,CDK17,FAM189A2,DCAF7,PRKAA1,KIF23,NCKAP1,FBXO6,SSX2IP,HDAC9,KIF5B,RALGPS2,IGF1R,CDK16,CENPJ,FAM13B,PAK2,PRKCI,TRIM21,SGK1,MAPK7,SIMC1,MPHOSPH9,PSMA5,NR4A1,CAPNS1,CYFIP2,BCAR1,EGFR,CRTC2,MAPKAPK2,TSC1,ARRB1,MAP3K5 |
| 1.403e-02 | -4.27 | V$NFKB_Q6 | MSigDB lists | V$NFKB_Q6 | 247 | 49 | 17758 | 2588 |
LASP1,BMF,GRIK2,NDRG2,TRIB2,DDR1,HOXB2,NFAT5,SPTB,PRRG4,CYP26A1,ICAM1,RND1,IRF2BPL,CTGF,CYR61,RGS3,LMO4,CD70,RFX5,NFKB2,XKR8,SEMA3B,TNIP1,SLC11A2,ATP1B1,CD40,ILK,PNKD,SEC14L2,CD83,FOXD2,CRTC2,PTGS2,TRIM47,PTPRJ,CAMK2N2,BFSP1,PAFAH1B3,SYT7,STAT6,NFKBIA,RAP2C,FAM117A,UACA,SP6,ATP1B3,JAK3,PTGES |
| 1.403e-02 | -4.27 | V$HNF4_DR1_Q3 | MSigDB lists | V$HNF4_DR1_Q3 | 247 | 49 | 17758 | 2588 |
GALK1,USH1C,ARHGEF7,PNPLA2,TP53,ERBB2,EGR3,CRABP2,PRR7,FBLN1,SLC25A35,SS18,LRRN2,FAM20C,CDK16,SGK1,DAB2IP,TNFRSF12A,ERBB3,SMYD5,NR2C1,CKAP4,SEMA3B,LAMP2,SOD1,SHMT1,MLEC,AGPS,ASXL1,DCHS1,KLK6,ATP1B1,F12,AIF1L,CLCN2,ZDHHC3,TCN2,PGF,PLEKHG6,INSR,GPRC5B,C19orf66,NR4A3,MAP3K11,OVOL1,TLE1,EIF4EBP2,SPRY4,FOXA1 |
| 1.404e-02 | -4.27 | Proteasome Degradation | WikiPathways | WP183 | 65 | 18 | 4455 | 729 |
PSMB4,PSME2,HLA-E,HLA-F,PSMD7,PSMD10,PSME1,PSMA4,HLA-A,HLA-B,PSMD1,PSMD3,PSMC2,UBE2D2,RPN2,HLA-C,PSMC1,PSMA5 |
| 1.406e-02 | -4.26 | SPINDLE_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | SPINDLE_ORGANIZATION_AND_BIOGENESIS | 11 | 5 | 17758 | 2588 |
KIF23,TUBG1,SUN2,KIF11,PRC1 |
| 1.406e-02 | -4.26 | ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT | MSigDB lists | ORGANELLAR_SMALL_RIBOSOMAL_SUBUNIT | 11 | 5 | 17758 | 2588 |
MRPS28,MRPS35,MRPS18A,MRPS36,MRPS15 |
| 1.406e-02 | -4.26 | KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP | MSigDB lists | KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP | 11 | 5 | 17758 | 2588 |
NRG2,RGS5,CDH1,ALCAM,DAPK1 |
| 1.406e-02 | -4.26 | WHITESIDE_CISPLATIN_RESISTANCE_UP | MSigDB lists | WHITESIDE_CISPLATIN_RESISTANCE_UP | 11 | 5 | 17758 | 2588 |
MX1,GDF15,ERBB3,ITGA7,PTGES |
| 1.406e-02 | -4.26 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | MSigDB lists | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | 11 | 5 | 17758 | 2588 |
UNC93B1,HSP90B1,LGMN,CNPY3,CTSB |
| 1.406e-02 | -4.26 | MODULE_293 | MSigDB lists | MODULE_293 | 11 | 5 | 17758 | 2588 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 1.406e-02 | -4.26 | REGULATION_OF_RAS_GTPASE_ACTIVITY | MSigDB lists | REGULATION_OF_RAS_GTPASE_ACTIVITY | 11 | 5 | 17758 | 2588 |
FGD6,TSC1,RALBP1,ARAP1,FGD1 |
| 1.406e-02 | -4.26 | CHUANG_OXIDATIVE_STRESS_RESPONSE_DN | MSigDB lists | CHUANG_OXIDATIVE_STRESS_RESPONSE_DN | 11 | 5 | 17758 | 2588 |
PLK1,CCNA2,UBE2C,NAB2,UTRN |
| 1.406e-02 | -4.26 | MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT | MSigDB lists | MITOCHONDRIAL_SMALL_RIBOSOMAL_SUBUNIT | 11 | 5 | 17758 | 2588 |
MRPS28,MRPS35,MRPS18A,MRPS36,MRPS15 |
| 1.406e-02 | -4.26 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | MSigDB lists | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | 11 | 5 | 17758 | 2588 |
ERBB2,NRG2,NRG1,ERBB3,AKT1 |
| 1.406e-02 | -4.26 | SMALL_RIBOSOMAL_SUBUNIT | MSigDB lists | SMALL_RIBOSOMAL_SUBUNIT | 11 | 5 | 17758 | 2588 |
MRPS28,MRPS35,MRPS18A,MRPS36,MRPS15 |
| 1.406e-02 | -4.26 | PID_P38_GAMMA_DELTA_PATHWAY | MSigDB lists | PID_P38_GAMMA_DELTA_PATHWAY | 11 | 5 | 17758 | 2588 |
SNTA1,CCND1,MAPK13,PKN1,MAPK12 |
| 1.406e-02 | -4.26 | negative regulation of Ras protein signal transduction | biological process | GO:0046580 | 41 | 12 | 16441 | 2455 |
ARHGAP24,TNK1,TIMP2,ARAP3,ITGA3,RASA2,BCL6,STMN3,DAB2IP,SPRY2,RASA1,ARHGAP35 |
| 1.406e-02 | -4.26 | G1/S transition of mitotic cell cycle | biological process | GO:0000082 | 162 | 35 | 16441 | 2455 |
CCNE2,ACVR1,PSME2,PSMD7,CUL1,PSMD10,PSME1,CCNB1,CDKN2C,CCND1,WEE1,E2F7,RB1,PSMD1,PCNA,PSMC2,CKS1B,CDKN1B,IQGAP3,CDKN2D,GFI1,PSMA5,CAMK2G,PSMB4,PKMYT1,CDK1,PSMA4,PRIM1,PSMD3,PLK2,CDCA5,E2F1,KLF11,PSMC1,DMPK |
| 1.406e-02 | -4.26 | cell cycle G1/S phase transition | biological process | GO:0044843 | 162 | 35 | 16441 | 2455 |
CCNE2,ACVR1,PSME2,PSMD7,CUL1,PSMD10,PSME1,CCNB1,CDKN2C,CCND1,WEE1,E2F7,RB1,PSMD1,PCNA,PSMC2,CKS1B,CDKN1B,IQGAP3,CDKN2D,GFI1,PSMA5,CAMK2G,PSMB4,PKMYT1,CDK1,PSMA4,PRIM1,PSMD3,PLK2,CDCA5,E2F1,KLF11,PSMC1,DMPK |
| 1.407e-02 | -4.26 | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP | MSigDB lists | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP | 183 | 38 | 17758 | 2588 |
ARHGEF3,PACSIN2,UGT8,PLSCR4,HSP90B1,NUAK1,RALBP1,THRA,XYLT1,TESK2,RASGRP3,GTF3A,NUP62CL,MARCH8,KIF13B,OSBPL3,RAB27B,TIPARP,TTLL1,CAMK2G,MBP,TCFL5,BCL9,MRS2,MBNL3,SESN1,AMZ2,PPP2R5A,PLA2G15,TRIM45,ABCB1,RAB31,CABIN1,STK39,PER3,TOB1,ATMIN,JARID2 |
| 1.407e-02 | -4.26 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP | 183 | 38 | 17758 | 2588 |
LZTFL1,SORT1,RASA2,GABRG2,TRIM68,HDAC9,TFAP4,ENTPD4,CTSC,LLGL2,PHTF1,PAK2,FOSB,SRR,FBXL14,MDFIC,KLF9,HES1,PGM1,COL6A2,TEF,PIK3R1,SYBU,SPTLC2,STK17B,RASA1,MAPKAPK2,PTGS2,STX10,PLOD2,SEMA4D,PTER,AMMECR1,NR4A3,OSMR,NR4A2,LSM14B,USP16 |
| 1.407e-02 | -4.26 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP | 183 | 38 | 17758 | 2588 |
GSDMD,CCNE2,TAOK2,UGT8,PTTG1,CCDC68,EXT2,TFAP4,RCN1,ENTPD4,DACT1,AOX1,MTMR10,MAP3K9,KCNS3,ANKRD12,ATRNL1,TSPAN13,SCARA3,MAST4,PRODH,KIAA0040,SYBU,CDC20,GRIN1,EGFR,CDK5R1,GALNT3,RND3,PVRL2,ZNF214,C1orf21,ABCB1,DTX4,PLD1,EPB41L4A,PPP2R5D,PKIA |
| 1.407e-02 | -4.26 | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_DN | 183 | 38 | 17758 | 2588 |
MRC2,GGA1,ZCCHC24,CIT,NDRG1,HABP4,ARL4C,NCKAP1,HES2,STIL,ANO1,SH2D4A,PSMD1,ANKS1B,CYP4F11,FRAS1,NPTXR,ZNF365,DLX4,RASGRF1,LONRF3,DSTN,CORO2A,ANTXR1,ARHGEF26,SOX13,FECH,AMMECR1,FGF18,TMC5,TRIM45,BMP1,ARRB1,PLXND1,DMWD,NCAPG2,LIFR,RUSC1 |
| 1.409e-02 | -4.26 | long-chain fatty acid metabolic process | biological process | GO:0001676 | 102 | 24 | 16441 | 2455 |
PLA2G4A,FADS2,FAM213B,CYP2J2,ELOVL3,CYP4F3,MAPKAPK2,PTGS2,CYP1A1,SLC27A6,FAAH,CYP2S1,SLC27A1,ABCD1,CYP2U1,ACSL4,LTA4H,SLC27A3,PTGES,ACOT7,MYO5A,ABCC1,GPX4,CYP1B1 |
| 1.409e-02 | -4.26 | single-organism carbohydrate catabolic process | biological process | GO:0044724 | 102 | 24 | 16441 | 2455 |
GALK1,PGM1,GAA,ENO2,PFKFB2,CALM1,HEXB,OGDHL,CALM3,PYGL,PKM,CALM2,DHDH,FUT2,PFKL,FUT8,FUT1,PGM2L1,DHTKD1,GLB1,PHKA2,PPP2R5D,PHKG2,GM2A |
| 1.409e-02 | -4.26 | multicellular organismal metabolic process | biological process | GO:0044236 | 102 | 24 | 16441 | 2455 |
COL9A3,ADAMTS2,MRC2,ADAM17,COL6A2,CTSB,P3H2,FURIN,P2RX7,COL18A1,KLK6,COL4A5,COL7A1,COL12A1,CTSL,MMP15,TRAM2,COL13A1,COL6A1,ADAM15,ADAMTS14,CTSD,TIPARP,COL16A1 |
| 1.409e-02 | -4.26 | core promoter binding | molecular function | GO:0001047 | 146 | 32 | 16491 | 2452 |
ELK4,RUNX2,PAX6,NKX3-1,SUZ12,SOX9,TP53,GATA3,HDAC6,GBX2,E2F7,RB1,TAF1B,MITF,TFAP2A,H2AFY,SIRT1,TFAP2C,ELK1,KDM3A,FOS,NR1D2,STAT6,STAT1,NR4A3,NLRC5,E2F1,HDAC1,IRF7,NR4A2,SOX8,E2F8 |
| 1.411e-02 | -4.26 | Rab3b (RAB3B, member RAS oncogene family) | protein interactions | 69908 | 4 | 3 | 16036 | 2547 |
TGFBR1,ACVR1,CALM1 |
| 1.411e-02 | -4.26 | Mapk1 (mitogen-activated protein kinase 1) | protein interactions | 26413 | 4 | 3 | 16036 | 2547 |
KLF11,BCL2L1,TP53 |
| 1.411e-02 | -4.26 | TUBE1 (tubulin, epsilon 1) | protein interactions | 51175 | 4 | 3 | 16036 | 2547 |
IGSF8,CD81,ICAM1 |
| 1.411e-02 | -4.26 | UNC5A (unc-5 netrin receptor A) | protein interactions | 90249 | 4 | 3 | 16036 | 2547 |
NTN1,DAP,DAPK1 |
| 1.411e-02 | -4.26 | DNAJC16 (DnaJ (Hsp40) homolog, subfamily C, member 16) | protein interactions | 23341 | 4 | 3 | 16036 | 2547 |
HLA-C,TMEM30A,SPINT2 |
| 1.411e-02 | -4.26 | C17orf75 (chromosome 17 open reading frame 75) | protein interactions | 64149 | 4 | 3 | 16036 | 2547 |
FAM91A1,WDR11,FAS |
| 1.411e-02 | -4.26 | SV40gp6 (large T antigen) | protein interactions | 1489531 | 4 | 3 | 16036 | 2547 |
RB1,KPNA2,TP53 |
| 1.411e-02 | -4.26 | MAP9 (microtubule-associated protein 9) | protein interactions | 79884 | 4 | 3 | 16036 | 2547 |
AURKB,SH3KBP1,TP53 |
| 1.411e-02 | -4.26 | HLA-H (major histocompatibility complex, class I, H (pseudogene)) | protein interactions | 3136 | 4 | 3 | 16036 | 2547 |
HLA-B,HLA-C,HLA-E |
| 1.411e-02 | -4.26 | Lmnb1 (lamin B1) | protein interactions | 116685 | 4 | 3 | 16036 | 2547 |
CCNA2,CCNB1,CDK1 |
| 1.411e-02 | -4.26 | BTN1A1 (butyrophilin, subfamily 1, member A1) | protein interactions | 696 | 4 | 3 | 16036 | 2547 |
PLK1,TRIM68,XDH |
| 1.411e-02 | -4.26 | Samhd1 (SAM domain and HD domain, 1) | protein interactions | 56045 | 4 | 3 | 16036 | 2547 |
CCNA2,CCNB1,CDK1 |
| 1.411e-02 | -4.26 | PROP1 (PROP paired-like homeobox 1) | protein interactions | 5626 | 4 | 3 | 16036 | 2547 |
PITX2,TLE1,CTNNB1 |
| 1.411e-02 | -4.26 | Rab6b (RAB6B, member RAS oncogene family) | protein interactions | 270192 | 4 | 3 | 16036 | 2547 |
TGFBR1,ACVR1,CALM1 |
| 1.411e-02 | -4.26 | DRP2 (dystrophin related protein 2) | protein interactions | 1821 | 4 | 3 | 16036 | 2547 |
DAG1,PRX,UTRN |
| 1.411e-02 | -4.26 | TMEM255B (transmembrane protein 255B) | protein interactions | 348013 | 4 | 3 | 16036 | 2547 |
AMZ2,WWP1,PHYHIP |
| 1.411e-02 | -4.26 | ROPN1B (rhophilin associated tail protein 1B) | protein interactions | 152015 | 4 | 3 | 16036 | 2547 |
AKAP3,RHPN1,SPA17 |
| 1.411e-02 | -4.26 | KIF6 (kinesin family member 6) | protein interactions | 221458 | 4 | 3 | 16036 | 2547 |
SNX16,HEATR5A,APPBP2 |
| 1.411e-02 | -4.26 | phospholipid metabolic process | biological process | GO:0006644 | 311 | 61 | 16441 | 2455 |
PLA2G4A,MTM1,INPPL1,CDS2,INPP5D,TMEM55B,PNPLA2,HEXB,ETNK1,PHOSPHO1,PLD2,ISYNA1,PLA2G16,CDIPT,PLPPR4,LPIN3,PIGL,PGAP1,CDS1,INPP5E,PTEN,OCRL,IMPAD1,SLC44A1,PLCG2,SERINC2,PIK3CA,SLC44A2,PIK3CD,PIKFYVE,FAR1,PLCB2,GPX4,PIGC,PLSCR1,PLAUR,LPGAT1,PIK3R1,PIP4K2C,SPTLC2,DGKE,SLC44A3,SGPP1,GPLD1,PLCG1,PI4K2B,ALDH5A1,AGPAT2,ABHD12,PLPP3,DOLPP1,DBI,PLA2G15,INPP4B,PNPLA6,DGAT2,SLC27A1,PIK3C2B,SAMD8,PLD1,CHPT1 |
| 1.411e-02 | -4.26 | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | MSigDB lists | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | 132 | 29 | 17758 | 2588 |
GSDMD,ACVR1,CXXC5,DYRK3,PCDH1,LGALS3,SLC2A8,RAPGEF2,SLC25A13,PPFIBP2,CDA,COL18A1,SLC35C1,SEPP1,IDH1,CA8,ALCAM,RHOB,EPS8L2,IRF2BPL,MOSPD3,NFKBIA,DGAT2,SERINC2,ABCB1,CTNND1,TTC39C,ALDH3A2,OSGIN1 |
| 1.415e-02 | -4.26 | Ald_DH_N | interpro domains | IPR016162 | 19 | 7 | 18293 | 2672 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.415e-02 | -4.26 | PAS_fold | interpro domains | IPR013767 | 19 | 7 | 18293 | 2672 |
AHRR,NCOA3,ARNT2,EPAS1,AHR,ARNT,NCOA2 |
| 1.415e-02 | -4.26 | Aldehyde_DH_dom | interpro domains | IPR015590 | 19 | 7 | 18293 | 2672 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.415e-02 | -4.26 | Ald_DH/histidinol_DH | interpro domains | IPR016161 | 19 | 7 | 18293 | 2672 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.415e-02 | -4.26 | Ald_DH_C | interpro domains | IPR016163 | 19 | 7 | 18293 | 2672 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.416e-02 | -4.26 | receptor tyrosine kinase binding | molecular function | GO:0030971 | 46 | 13 | 16491 | 2452 |
DOCK4,PLCG1,FNTA,PCNA,ELMO2,SHC3,PIK3R1,LRP4,TP53,NRG1,TOB1,ARHGEF16,SOCS5 |
| 1.416e-02 | -4.26 | positive regulation of ossification | biological process | GO:0045778 | 81 | 20 | 16441 | 2455 |
CTHRC1,RUNX2,ACVR1,WNT10B,ANO6,P2RX7,OSR2,ILK,CTNNBIP1,BMP2,GNAS,CTNNB1,CYR61,NPNT,FAM20C,IL6ST,BMP7,TFAP2A,SUCO,OSR1 |
| 1.416e-02 | -4.26 | microtubule organizing center organization | biological process | GO:0031023 | 81 | 20 | 16441 | 2455 |
PLK1,GCC2,PPP1R12A,UXT,CNTROB,STIL,KIF11,CDK1,SSX2IP,CKAP5,CTNNB1,CENPJ,TUBGCP6,PLK4,NEK2,AURKA,PKD2,NDE1,SGOL1,FBXW5 |
| 1.417e-02 | -4.26 | GTPASE_ACTIVITY | MSigDB lists | GTPASE_ACTIVITY | 99 | 23 | 17758 | 2588 |
RAB3B,RHOA,GNAL,ARL4C,MRAS,ARFRP1,RAB6A,SEPT4,GNB2,GNA11,RHEB,RHOB,ARF4,GNAS,DIRAS3,RAC2,RND3,DNM1L,ARL1,RAB31,RAB27B,ARL4D,ARF6 |
| 1.417e-02 | -4.26 | LABBE_TGFB1_TARGETS_UP | MSigDB lists | LABBE_TGFB1_TARGETS_UP | 99 | 23 | 17758 | 2588 |
TGIF1,AASS,GRIK2,CAST,IQGAP1,SAT1,FURIN,LITAF,ITPR2,PDGFB,BEX2,PDGFA,CAPN2,PTGS2,CTGF,CYR61,KCNK5,CAPG,BMP1,SGK1,CITED2,CPE,ABCG1 |
| 1.417e-02 | -4.26 | BDNF signaling pathway | WikiPathways | WP2380 | 144 | 34 | 4455 | 729 |
PRKAA2,CASP3,ACACB,SORT1,RPS6KA1,PRKAA1,SIRPA,BMP2,SPP1,CTNNB1,CDKL5,SHC3,DPYSL2,DLG1,NCAM1,MAPK7,TIAM1,FRS3,RASGRF1,ADAM17,AKT1,PIK3R1,GRIN1,ELK1,FOS,RANBP9,CDK5R1,IRS2,PTPRF,PLCG1,FYN,NFKBIA,STAT1,RPS6KA3 |
| 1.419e-02 | -4.26 | Pept_his_AS | interpro domains | IPR025660 | 11 | 5 | 18293 | 2672 |
CTSL,TINAGL1,CTSC,CTSB,CTSV |
| 1.419e-02 | -4.26 | Amidohydro-rel | interpro domains | IPR006680 | 11 | 5 | 18293 | 2672 |
DPYSL5,DPYSL4,AMDHD1,DPYSL2,DPYSL3 |
| 1.419e-02 | -4.26 | Frizzled | interpro domains | IPR000539 | 11 | 5 | 18293 | 2672 |
FZD5,FZD4,FZD7,FZD6,SMO |
| 1.419e-02 | -4.26 | Pointed_dom | interpro domains | IPR003118 | 11 | 5 | 18293 | 2672 |
ETS2,ETV7,ETS1,ELF5,ELF3 |
| 1.419e-02 | -4.26 | Filamin/ABP280_repeat-like | interpro domains | IPR017868 | 11 | 5 | 18293 | 2672 |
TRIM3,TRIM2,AREL1,KDELC2,TRIM45 |
| 1.420e-02 | -4.25 | negative regulation of canonical Wnt signaling pathway | biological process | GO:0090090 | 151 | 33 | 16441 | 2455 |
CTHRC1,PSME2,SOX9,LRP4,PSMD7,PSMD10,AES,PSME1,ZNRF3,APC2,FZD6,PPP2R3A,BMP2,PSMD1,DACT1,PSMC2,DAB2IP,WNT3A,DVL2,PSMA5,PSMB4,KREMEN2,AMER1,PRICKLE1,NPHP3,PSMA4,ANKRD6,PSMD3,NKD1,WWTR1,TBX18,CTNND1,PSMC1 |
| 1.421e-02 | -4.25 | BRUNO_HEMATOPOIESIS | MSigDB lists | BRUNO_HEMATOPOIESIS | 62 | 16 | 17758 | 2588 |
GALK1,CD55,NDRG1,SESN1,DAG1,REPS1,PRDX4,RCN1,NOV,PTGS2,H1F0,CTSC,CD9,GLB1,CPE,S100A6 |
| 1.421e-02 | -4.25 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN | 62 | 16 | 17758 | 2588 |
AGPS,DUSP23,FAM102B,AURKB,IFIT3,PDGFB,MECOM,METTL7A,SH2D3C,TBX1,TBX18,TFAP2A,STAT1,DUSP10,KANK2,IFIT1 |
| 1.421e-02 | -4.25 | LYPD6 (LY6/PLAUR domain containing 6) | protein interactions | 130574 | 30 | 10 | 16036 | 2547 |
SOAT1,TMEM68,TCTN2,CELSR2,LPGAT1,TMEM245,DNM2,MINPP1,TMX1,CKAP4 |
| 1.421e-02 | -4.25 | RAB27A (RAB27A, member RAS oncogene family) | protein interactions | 5873 | 30 | 10 | 16036 | 2547 |
EXPH5,MLPH,FBXO6,SYTL4,LRIF1,MYRIP,SYTL3,MYO5A,SYTL2,RIMS2 |
| 1.423e-02 | -4.25 | NTR | smart domains | SM00206 | 4 | 3 | 9131 | 1455 |
TIMP3,TIMP2,TIMP1 |
| 1.423e-02 | -4.25 | Aldolase_II | smart domains | SM01007 | 4 | 3 | 9131 | 1455 |
APIP,ADD3,ADD1 |
| 1.424e-02 | -4.25 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP | 42 | 12 | 17758 | 2588 |
IL1R1,SERPINE2,NLRX1,GCAT,JKAMP,PTTG1,BUB1,GTF3A,MANF,SLC25A5,S100A6,RASGRP2 |
| 1.424e-02 | -4.25 | ZUCCHI_METASTASIS_DN | MSigDB lists | ZUCCHI_METASTASIS_DN | 42 | 12 | 17758 | 2588 |
ZYX,SEC61B,RHOA,LGALS3,AREG,CST3,SAT1,NFKBIA,STRN4,CLDN4,TACSTD2,SEMA3B |
| 1.424e-02 | -4.25 | ZHAN_V2_LATE_DIFFERENTIATION_GENES | MSigDB lists | ZHAN_V2_LATE_DIFFERENTIATION_GENES | 42 | 12 | 17758 | 2588 |
DCTN6,PEX5,IRAK1,NR3C1,BIK,AKR1B1,CAPNS1,GLB1,ATP1B3,OAT,BARD1,IRF1 |
| 1.424e-02 | -4.25 | KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION | MSigDB lists | KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION | 42 | 12 | 17758 | 2588 |
IRS2,INSR,ATP1A1,SCNN1A,PIK3R1,PIK3CA,SGK1,PIK3CD,ATP1B1,ATP1B3,NR3C2,SLC9A3R2 |
| 1.424e-02 | -4.25 | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | MSigDB lists | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | 42 | 12 | 17758 | 2588 |
MAGED2,NOV,DSTN,MYLK,PKD2,TNS1,EMP2,HSPB1,MYLIP,CSRP2,EGFR,MAP1B |
| 1.427e-02 | -4.25 | pancreas-ampulla_of_Vater-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-ampulla_of_Vater-carcinoma-ductal_carcinoma | 47 | 13 | 17775 | 2585 |
GNAS,MAN2B2,CTNNB1,CDH1,IQCE,MSH2,PIK3CA,TP53,ANXA9,BLVRA,EGFR,SCN3A,MSH6 |
| 1.427e-02 | -4.25 | soft_tissue-sarcoma | COSMIC cancer mutations | soft_tissue-sarcoma | 47 | 13 | 17775 | 2585 |
GNAS,CDKN2C,RB1,SS18,CTNNB1,AKT1,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR |
| 1.429e-02 | -4.25 | GCM_MAP4K4 | MSigDB lists | GCM_MAP4K4 | 166 | 35 | 17758 | 2588 |
GPR107,SCD5,LRP4,ADO,C1orf198,APC2,APPBP2,ZNF275,CCDC92,NAPG,SESN3,ANKS1B,CASC4,IL6ST,FRYL,DDHD2,DLG1,ARNT2,NPTN,CCDC88A,TBC1D10B,CLCN3,ZNF84,KIAA1109,DNAJB14,ERBB2IP,BBS2,PLEKHB1,ULK2,GPRC5B,PHLPP2,TMEM30A,TMOD2,TANC2,ATMIN |
| 1.429e-02 | -4.25 | GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_UP | MSigDB lists | GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_UP | 166 | 35 | 17758 | 2588 |
DOC2A,CASP3,CCDC109B,CAMK1D,CDIPT,COMMD5,BAHD1,CENPN,CHPF,ANK1,EFR3A,CST3,AIM1,FBXL14,FAIM,ETV7,ERLEC1,AGPS,EIF5A2,CR2,DNAJB14,CCNF,FOS,CDK1,DCP2,ARHGAP35,BOLA3,ARHGEF19,CTNS,E2F1,FHL1,CENPE,AFAP1,CCDC97,FBXW5 |
| 1.429e-02 | -4.25 | INGRAM_SHH_TARGETS_UP | MSigDB lists | INGRAM_SHH_TARGETS_UP | 121 | 27 | 17758 | 2588 |
HES1,PLSCR1,NR3C1,NR4A1,TSC22D3,ASAH1,ITPR3,OAT,DOCK5,SEPP1,ABCD4,RASSF8,MFAP3L,ENPP1,SLC6A6,ADD3,IGF1R,CTGF,SNX18,PTK7,UBE2J1,KLF9,CMPK2,SLC27A3,EPHX1,CYP1B1,DUSP1 |
| 1.429e-02 | -4.25 | CRX_NRL_DN.V1_DN | MSigDB lists | CRX_NRL_DN.V1_DN | 121 | 27 | 17758 | 2588 |
QSOX1,SGCE,INPPL1,ERMAP,FMN1,GRIK2,NR4A1,FRMD6,HEBP1,RASA2,SLC25A13,ELOVL7,SDC4,PDIA3,RBP7,NIN,PTER,BAX,TNPO2,TNFRSF12A,NTN4,RTKN2,ECE1,FZD5,RAB27B,TSPAN33,FAM134C |
| 1.429e-02 | -4.25 | V$IRF2_01 | MSigDB lists | V$IRF2_01 | 121 | 27 | 17758 | 2588 |
DDX58,GSDMD,PCGF5,PDGFC,SORBS1,IL15RA,USP18,SYNE2,TAP1,RGAG1,CCDC68,PSME1,LDB2,KDM3A,DTX3L,TAPBP,RNF220,CCDC6,TBX1,MITF,DLG1,MAP3K11,FXYD5,DUSP10,DLX4,NR3C2,RIMS2 |
| 1.429e-02 | -4.25 | tonsil | COSMIC cancer mutations | tonsil | 138 | 30 | 17775 | 2585 |
KIF20A,AKT1,GUSB,MACC1,OGDHL,TP53,ERBB2,WHSC1,TGFBR1,PDGFRL,KIF13A,ITPR2,NOTCH2,ZFAND5,MYOM1,EGFR,NIN,DHDH,ARHGEF10L,CCND1,BTG3,RB1,TAPBP,MUC16,FAT4,PTEN,PIK3CA,FHL1,COL16A1,ZNF117 |
| 1.432e-02 | -4.25 | Viral carcinogenesis | KEGG pathways | ko05203 | 205 | 44 | 6908 | 1076 |
CCNE2,CASP3,HLA-E,HLA-F,RASA2,TRAF2,HDAC11,TP53,EGR3,HDAC6,PRKACA,HLA-A,HDAC9,CCND1,RB1,CCNA2,SP100,IL6ST,RANBP1,DLG1,BAX,PIK3CA,CDKN1B,PIK3CD,HLA-C,NFKB2,SYK,RHOA,CDC20,PIK3R1,SCRIB,PKM,GTF2A2,CDK1,MAPKAPK2,HLA-B,JAK1,RBL1,NFKBIA,HDAC1,IRF7,TRAF5,JAK3,PSMC1 |
| 1.432e-02 | -4.25 | Viral carcinogenesis | KEGG pathways | hsa05203 | 205 | 44 | 6908 | 1076 |
CCNE2,CASP3,HLA-E,HLA-F,RASA2,TRAF2,HDAC11,TP53,EGR3,HDAC6,PRKACA,HLA-A,HDAC9,CCND1,RB1,CCNA2,SP100,IL6ST,RANBP1,DLG1,BAX,PIK3CA,CDKN1B,PIK3CD,HLA-C,NFKB2,SYK,RHOA,CDC20,PIK3R1,SCRIB,PKM,GTF2A2,CDK1,MAPKAPK2,HLA-B,JAK1,RBL1,NFKBIA,HDAC1,IRF7,TRAF5,JAK3,PSMC1 |
| 1.434e-02 | -4.24 | post-translational protein modification | biological process | GO:0043687 | 382 | 73 | 16441 | 2455 |
GALNT12,NANS,PIGL,MUC16,NUP210,MUC4,SP100,RPN2,LMAN1,TFG,MGAT5,ATG4D,SEC23A,GALNT7,SLC17A5,ICMT,MCFD2,MAN2A2,DDOST,AREG,DOLPP1,B4GALT3,ST3GAL1,CBX4,CMAS,TRAPPC10,DHPS,MAN1A2,GNE,PDIA3,CTSZ,B4GALT4,ADAMTSL4,PGAP1,ATG4A,CALR,CTSC,MGAT1,ARSG,MGAT4A,ALG13,FUT8,STT3B,SLC35A1,PPP6R1,NUP85,TMED2,GCNT1,GFPT1,PIGC,B3GNT7,B3GNT2,MLEC,PLAUR,EIF5A2,MGAT4B,FURIN,C1GALT1C1,COL7A1,ARSK,FUCA1,GALNT3,SERPINA1,UAP1,PIAS2,CTSA,GLB1,ALG2,NUP37,ARSB,NUP58,RAD21,PHC1 |
| 1.436e-02 | -4.24 | GSE17721_LPS_VS_POLYIC_16H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_16H_BMDM_DN | 189 | 39 | 17758 | 2588 |
FAM89A,PARP12,S100A11,HMGN3,F11R,LPIN3,CACNB4,SLC44A2,TMBIM6,TAX1BP3,IRF2,TSPAN13,TLE6,RBMS2,PARP9,PSRC1,MMD,NR3C1,LPGAT1,STAT4,SAT1,NUB1,PLEKHO1,NFE2L1,UTRN,C15orf39,IFIT3,PTPRF,SCARB2,TRIOBP,PRDM5,ARFGAP3,FAM117A,RBM43,MAD2L1BP,SERPINB1,L1CAM,JARID2,CTDSP1 |
| 1.436e-02 | -4.24 | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDM_UP | 189 | 39 | 17758 | 2588 |
MRC2,FLYWCH2,EPHA4,BIK,LYNX1,ITPR2,PHLDA1,SNTA1,TIMP1,DACT1,MTMR10,FAM63A,AKR1B1,OSTF1,ASH2L,ECE1,CITED2,CKS2,SIRT1,SHMT1,NR4A1,STAT4,CR2,ZFAND5,RHOB,CD83,ATP13A2,SOX13,IRS2,ONECUT1,ZFP30,CSF1,SPAG7,PPP1CB,NFKBIZ,SLC27A3,ACOT7,JARID2,FGD1 |
| 1.436e-02 | -4.24 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN | 189 | 39 | 17758 | 2588 |
PNISR,ARMCX3,MCTP2,FLOT1,BLCAP,KIAA1147,DNAJB9,CD109,ITGA3,TIMP1,KIAA1107,ZFP36,PAPSS1,N4BP3,ATRNL1,EGLN3,S100A6,CDKN2AIP,HPS3,TMEM43,RAPGEF2,FNDC3A,MCFD2,ALCAM,RANBP9,ATP10D,CRISPLD2,FRMD4B,SOCS3,AMZ2,PTPRJ,TWSG1,ITGA7,APPL2,GEM,MAP3K5,WDR91,ABCA1,MAMDC2 |
| 1.436e-02 | -4.24 | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_DN | 189 | 39 | 17758 | 2588 |
HECA,BMF,PINK1,JKAMP,RPS6KA1,CNOT8,DCAF7,CCM2,SMARCAL1,DPP8,GNB2,C9orf69,CXCL16,RNF220,PIK3CD,PPP1CA,CTDSP2,FAM134C,ORAI2,TAF5,TRIM8,TACC1,NFE2L1,UBAC1,TNFAIP8L1,CBL,ILK,DDX23,FUCA1,ATXN7L3,SH2D3C,MADD,CSTF2,ZDHHC7,CTNND1,PLIN3,CTBP1,SRSF9,CTDSP1 |
| 1.436e-02 | -4.24 | GSE17721_0.5H_VS_8H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_8H_CPG_BMDM_UP | 189 | 39 | 17758 | 2588 |
FBLIM1,SORT1,ADD1,HEBP1,ITGA6,GMPR,ASAH1,RHPN2,SLC25A35,SS18,SH3BP1,SIVA1,TMEM51,ADAM15,ABCD1,STT3B,ETHE1,RNF26,PLCB2,NUP85,PHKG2,TMED2,S100A6,GCNT1,TEF,ITCH,CORO2A,CASP9,TEP1,MRPS35,C4orf27,FUCA1,PLA2G15,HMGA1,SLC27A3,PRR15,MYL12B,CSRP2,FAM134B |
| 1.437e-02 | -4.24 | AHCY (adenosylhomocysteinase) | protein interactions | 191 | 62 | 17 | 16036 | 2547 |
SIRT1,LGALS3,CUL4B,XIAP,CUL1,PYGL,FBXO6,SDC1,H2AFV,APPBP2,TP73,HLA-B,TRAF3IP1,PAPSS1,SERPINB6,AHCY,HSPB1 |
| 1.437e-02 | -4.24 | KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) | protein interactions | 3815 | 62 | 17 | 16036 | 2547 |
SPRED1,PTPRU,CD63,INPP5D,PIK3R1,TEC,YES1,CBL,RASA1,SH3KBP1,PLCG1,FYN,STAT1,CD9,CD81,JAK3,SOCS5 |
| 1.437e-02 | -4.24 | CDH2 (cadherin 2, type 1, N-cadherin (neuronal)) | protein interactions | 1000 | 62 | 17 | 16036 | 2547 |
GAA,GRIK2,PIK3R1,GRIN1,NENF,DDR1,KTN1,PDIA4,CCNA2,CTNNB1,RYK,IARS2,ARVCF,PTBP3,PRKCDBP,GRIN2D,CTNND1 |
| 1.438e-02 | -4.24 | ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_UP | 83 | 20 | 17758 | 2588 |
B3GALT6,CASK,ALDH2,ZNF84,ALDH6A1,ITCH,ZNF320,BNIP3L,MDK,BTG1,BANK1,RBL1,DCK,SIVA1,PHTF1,SGK3,TNFRSF18,CHPT1,MED30,ATP2B1 |
| 1.438e-02 | -4.24 | YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta) | protein interactions | 10971 | 427 | 85 | 16036 | 2547 |
LMO7,TNK1,THRA,CAMKK1,IQGAP1,KLC2,PKP2,RASGRP3,SPTB,BCAP31,ARHGEF16,CDK14,PAK6,WEE1,RGS3,ZFP36,CDKN1B,DAB2IP,ACSL4,MAP3K3,ING1,PFKFB2,PANK1,RNF11,KIF1C,PRKCQ,MCFD2,CBL,CDC25C,GIGYF1,VCP,OPTN,IRS2,MPRIP,WWTR1,IARS2,PIK3C2B,PDXK,HSPB1,MYL12B,CAPN1,CDK17,FRMD6,CBLL1,KIF23,TXNDC9,FBXO6,SPR,FBLN1,EFNB1,SSX2IP,LMNA,KIF5B,VASP,PFKL,CDK16,ZNRF2,ADCK2,KLC3,BAX,CTPS1,DAPK1,ACTA2,SGK1,WWP1,AHCY,ALDH7A1,CALM1,PLEKHA7,CAPNS1,PKM,EGFR,CRTC2,NCOA3,TSC1,BANK1,H1F0,SH3BP4,E2F1,ARRB1,CDK18,CABIN1,MAP3K5,NDE1,TBC1D4 |
| 1.441e-02 | -4.24 | PCP/CE pathway | REACTOME pathways | R-HSA-4086400 | 91 | 22 | 8202 | 1235 |
RHOA,PSMB4,FZD4,PSME2,PSMD7,PRICKLE1,PSMD10,SCRIB,PSME1,ROR1,PSMA4,FZD6,FZD7,RAC2,PSMD1,PSMD3,PSMC2,RYK,FZD5,PSMC1,DVL2,PSMA5 |
| 1.443e-02 | -4.24 | transcription factor binding | molecular function | GO:0008134 | 516 | 95 | 16491 | 2452 |
GAS2L1,PAX6,ADD1,EPAS1,THRA,TSC22D3,HDAC11,TP53,GATA3,TP73,CCND1,SP100,CTNNB1,LMO4,PSMC2,FOSB,ZBTB49,TWIST1,ARNT2,MED30,SIRT1,CXXC5,ASXL1,DRAP1,ICMT,GTF2A2,OPTN,GABARAPL1,RBL1,GNPTAB,PRDM5,TLE1,HDAC1,PSMC1,ARNT,TTC8,NKX3-1,RUNX2,DGKQ,SOX9,PSMD10,HMGN3,SORBS3,HES2,TRIB2,ETS1,PSIP1,AIP,TEAD3,HDAC9,WWP2,RB1,TAF1B,GATA2,BHLHE41,TOX2,TFAP2A,BRD7,MDFIC,PIM1,LRIF1,NCOA2,EEF1D,MDFI,HES1,PIK3R1,FHL2,PPARA,PRICKLE1,FOS,BBS2,BCL10,CRTC2,CNOT2,PITX2,NCOA3,NAAA,HTT,SETD3,NFKBIA,NAB2,NR4A3,PIAS2,E2F1,ARRB1,NR4A2,HMGA1,SOX8,USF2,CBX5,CTBP1,RARG,AHR,FOXA1,TMEM173 |
| 1.444e-02 | -4.24 | SKP1 (S-phase kinase-associated protein 1) | protein interactions | 6500 | 174 | 39 | 16036 | 2547 |
NFKBIE,NUAK1,SUZ12,FBXO2,TP53,CDCA3,CUL1,FBXO6,KCTD9,TFAP4,CCND1,CCNA2,CTNNB1,FBXO7,TUBG1,TRIM21,CKS1B,CDKN1B,CRY2,DAB2IP,APIP,PPP1CA,PIP4K2C,FBXO8,FBXO9,MCFD2,CCNF,BORA,VCP,BTG1,CCDC6,CORO1C,NFKBIA,AURKA,FBXO44,CENPE,FBXO27,ZC3HC1,FBXW5 |
| 1.444e-02 | -4.24 | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN | MSigDB lists | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN | 57 | 15 | 17758 | 2588 |
SPP1,NOV,IQGAP1,SAT1,ADAM15,AES,CTSZ,CTSD,SYK,PSMA4,SP4,PDIA4,WBP5,SOCS3,RASGRP2 |
| 1.448e-02 | -4.24 | rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | rosette-forming_glioneuronal_tumour | 15 | 6 | 17775 | 2585 |
GNAS,AKT1,IDH1,EGFR,RET,PIK3CA |
| 1.448e-02 | -4.24 | villous | COSMIC cancer mutations | villous | 15 | 6 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 1.448e-02 | -4.24 | lipoma | COSMIC cancer mutations | lipoma | 15 | 6 | 17775 | 2585 |
GNAS,ERBB2,RB1,CTNNB1,AKT1,PIK3CA |
| 1.448e-02 | -4.24 | large_intestine-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-adenoma-tubulovillous | 15 | 6 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 1.448e-02 | -4.24 | tubulovillous | COSMIC cancer mutations | tubulovillous | 15 | 6 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 1.448e-02 | -4.24 | large_intestine-rectum-adenoma-villous | COSMIC cancer mutations | large_intestine-rectum-adenoma-villous | 15 | 6 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 1.448e-02 | -4.24 | large_intestine-colon-adenoma-tubular | COSMIC cancer mutations | large_intestine-colon-adenoma-tubular | 15 | 6 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA,TP53 |
| 1.448e-02 | -4.24 | central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour | 15 | 6 | 17775 | 2585 |
GNAS,AKT1,IDH1,EGFR,RET,PIK3CA |
| 1.448e-02 | -4.24 | thymus-thymic_carcinoma | COSMIC cancer mutations | thymus-thymic_carcinoma | 15 | 6 | 17775 | 2585 |
ERBB2,AKT1,PTEN,EGFR,PIK3CA,TP53 |
| 1.448e-02 | -4.24 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-epithelioid | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-epithelioid | 15 | 6 | 17775 | 2585 |
RB1,CTNNB1,CDH1,PTEN,PIK3CA,TP53 |
| 1.448e-02 | -4.24 | large_intestine-colon-adenoma-villous | COSMIC cancer mutations | large_intestine-colon-adenoma-villous | 15 | 6 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 1.448e-02 | -4.24 | large_intestine-colon-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-colon-adenoma-tubulovillous | 15 | 6 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 1.448e-02 | -4.24 | large_intestine-adenoma-tubular | COSMIC cancer mutations | large_intestine-adenoma-tubular | 15 | 6 | 17775 | 2585 |
GNAS,CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 1.448e-02 | -4.23 | endoplasmic reticulum chaperone complex | cellular component | GO:0034663 | 11 | 5 | 17570 | 2579 |
DNAJB11,DNAJC10,HSP90B1,P4HB,PDIA6 |
| 1.448e-02 | -4.23 | MHC class I protein complex | cellular component | GO:0042612 | 11 | 5 | 17570 | 2579 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 1.451e-02 | -4.23 | BCAT.100_UP.V1_UP | MSigDB lists | BCAT.100_UP.V1_UP | 47 | 13 | 17758 | 2588 |
ENO2,CRYM,DNAJC3,ETV5,BIK,FUT1,ABCB1,CD9,PLEKHF1,SERPINI1,DUSP4,GAD1,GCNT1 |
| 1.451e-02 | -4.23 | OXFORD_RALA_OR_RALB_TARGETS_UP | MSigDB lists | OXFORD_RALA_OR_RALB_TARGETS_UP | 47 | 13 | 17758 | 2588 |
CCND1,CCNE2,PPIF,ZWINT,PSMD3,WHSC1,AURKB,PLXNA1,HMGA1,SLC20A1,UBE2C,CDK1,SAC3D1 |
| 1.451e-02 | -4.23 | YAMASHITA_LIVER_CANCER_STEM_CELL_UP | MSigDB lists | YAMASHITA_LIVER_CANCER_STEM_CELL_UP | 47 | 13 | 17758 | 2588 |
WEE1,SOX9,MYLK,CLDN4,MAPK13,MAP3K5,FZD5,MERTK,CCNB2,DDR1,RARG,ELF3,DUSP1 |
| 1.451e-02 | -4.23 | LEADING_EDGE | MSigDB lists | LEADING_EDGE | 47 | 13 | 17758 | 2588 |
TSC1,ARAP3,S100A11,FGD6,EZR,CTTN,ARF6,BCAR1,SCYL3,CCDC88A,MYO5A,S100A6,FGD1 |
| 1.451e-02 | -4.23 | HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY | MSigDB lists | HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY | 47 | 13 | 17758 | 2588 |
GCLM,SOD1,MBP,TXN,NQO1,GCLC,PPP2R4,SOD2,ERCC2,CDKN2D,PRDX4,ABCC1,GPX4 |
| 1.451e-02 | -4.23 | MICROTUBULE_ASSOCIATED_COMPLEX | MSigDB lists | MICROTUBULE_ASSOCIATED_COMPLEX | 47 | 13 | 17758 | 2588 |
KIF5B,KIF3C,MAP2,KLC2,KIF23,KIF2C,KIF11,CLIP2,RANBP9,APPBP2,MAP1B,ATG4A,ATG4D |
| 1.452e-02 | -4.23 | lamellipodium membrane | cellular component | GO:0031258 | 19 | 7 | 17570 | 2579 |
VASP,PIEZO1,ITGAV,NCKAP1,APC2,ANTXR1,SYNE2 |
| 1.453e-02 | -4.23 | V$MZF1_02 | MSigDB lists | V$MZF1_02 | 224 | 45 | 17758 | 2588 |
CCDC24,MRC2,ARMCX3,PPP1R12A,HOXB7,CHCHD7,TP53,EGR3,BAHD1,XPR1,MECOM,PHYHIP,VASP,CYP1A1,OXCT1,IGF1R,PPP1R10,PIK3AP1,ANKS1B,LHX6,KCNS3,TNPO2,VAT1,RFX5,WBP4,ZNF462,ASXL1,PHLDB3,CBX6,RUNX3,ROR1,PNKD,SP4,RASGRP2,NFIX,PTPRF,FYN,KLF12,SYT7,H1F0,C1orf21,RAP2C,FAM117A,GRIN2D,EFNA1 |
| 1.456e-02 | -4.23 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN | 52 | 14 | 17758 | 2588 |
PLK1,CDKN2C,FAM111A,CCNA2,TIMM8A,NEIL3,CDC20,NDC80,AURKA,CCNF,DHRS3,BARD1,E2F8,ESPL1 |
| 1.456e-02 | -4.23 | BROWNE_HCMV_INFECTION_4HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_4HR_UP | 52 | 14 | 17758 | 2588 |
PTGS2,CASK,GPRC5B,AREG,GRIK2,PTK7,IL6ST,FGF18,SOD2,NR4A3,IFIT1,PDE4D,IFIT3,RANBP9 |
| 1.456e-02 | -4.23 | MORF_BUB1 | MSigDB lists | MORF_BUB1 | 52 | 14 | 17758 | 2588 |
HMMR,PLK1,ZWINT,DLGAP5,FOXM1,KIF14,NDC80,WHSC1,USP1,BUB1,KIF2C,CCNB1,KIF11,ESPL1 |
| 1.456e-02 | -4.23 | KEGG_MTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_MTOR_SIGNALING_PATHWAY | 52 | 14 | 17758 | 2588 |
PRKAA2,PGF,TSC1,RPS6KA2,AKT1,RPS6KA1,PRKAA1,PIK3R1,PIK3CA,CAB39,PIK3CD,ULK2,RHEB,RPS6KA3 |
| 1.459e-02 | -4.23 | CDK3 (cyclin-dependent kinase 3) | protein interactions | 1018 | 48 | 14 | 16036 | 2547 |
CCNE2,CCNC,RB1,B3GNT2,CCNA2,CDKN1C,PPARA,E2F1,CUL1,CDKN1B,CKS1B,CDK1,CDK5R1,CKS2 |
| 1.459e-02 | -4.23 | MAPK10 (mitogen-activated protein kinase 10) | protein interactions | 5602 | 48 | 14 | 16036 | 2547 |
CDKN2C,TNIP1,TP53,EZR,DUSP10,HDAC1,ARRB1,CDKN1B,PKMYT1,ELK1,WDR62,KIF26A,HDAC9,DUSP1 |
| 1.459e-02 | -4.23 | UBE2V2 (ubiquitin conjugating enzyme E2 variant 2) | protein interactions | 7336 | 48 | 14 | 16036 | 2547 |
MOB4,SEC23A,ZYX,TRIM5,SHPRH,TRAF2,MKRN3,RNF11,XIAP,CPLX1,LRIF1,EGFR,VPS26A,BCL10 |
| 1.462e-02 | -4.23 | response to acid chemical | biological process | GO:0001101 | 294 | 58 | 16441 | 2455 |
PRKAA2,CASP3,CPEB4,SOX9,RET,PRKAA1,COL18A1,SELL,BCL2L1,CCNB1,PDGFB,ICAM1,CAPN2,TGFBR3,SP100,CTGF,COL6A1,CD9,TFAP2A,AKR1B1,TMBIM6,CDKN1B,IGFBP2,HMGCL,LRP11,WNT3A,CDKN2D,DUSP1,PDGFC,SHMT1,RHOA,AKT1,WNT10B,FZD4,ASXL1,MICB,YES1,PDK3,MEST,EGFR,FZD7,GNAS,PTGS2,TIMP3,TBX1,PTK7,SH3BP4,E2F1,DGAT2,PKD2,OSR1,PTGES,COL16A1,ABCA1,RARG,DRD1,PHC1,RRAGD |
| 1.463e-02 | -4.22 | REGULATION_OF_MEMBRANE_POTENTIAL | MSigDB lists | REGULATION_OF_MEMBRANE_POTENTIAL | 15 | 6 | 17758 | 2588 |
SOD1,BCL2L1,KCNMB4,AIFM3,IFI6,BAX |
| 1.463e-02 | -4.22 | SINGH_NFE2L2_TARGETS | MSigDB lists | SINGH_NFE2L2_TARGETS | 15 | 6 | 17758 | 2588 |
GCLM,TXN,GRK6,NQO1,GCLC,ABCC1 |
| 1.463e-02 | -4.22 | OZANNE_AP1_TARGETS_UP | MSigDB lists | OZANNE_AP1_TARGETS_UP | 15 | 6 | 17758 | 2588 |
EZR,PRKCQ,LGALS3,STAT6,EGFR,CAPG |
| 1.463e-02 | -4.22 | TUBE_MORPHOGENESIS | MSigDB lists | TUBE_MORPHOGENESIS | 15 | 6 | 17758 | 2588 |
GCLM,SOD1,KCNMB4,GCLC,LMO4,BCL10 |
| 1.463e-02 | -4.22 | PID_ARF6_DOWNSTREAM_PATHWAY | MSigDB lists | PID_ARF6_DOWNSTREAM_PATHWAY | 15 | 6 | 17758 | 2588 |
PLD2,RHOA,PLD1,ARF6,TIAM1,PLAUR |
| 1.463e-02 | -4.22 | BIOCARTA_LONGEVITY_PATHWAY | MSigDB lists | BIOCARTA_LONGEVITY_PATHWAY | 15 | 6 | 17758 | 2588 |
SOD1,IGF1R,AKT1,PIK3R1,SOD2,PIK3CA |
| 1.463e-02 | -4.22 | PID_ERBB_NETWORK_PATHWAY | MSigDB lists | PID_ERBB_NETWORK_PATHWAY | 15 | 6 | 17758 | 2588 |
ERBB2,NRG2,NRG1,ERBB3,AREG,EGFR |
| 1.463e-02 | -4.22 | SCHAVOLT_TARGETS_OF_TP53_AND_TP63 | MSigDB lists | SCHAVOLT_TARGETS_OF_TP53_AND_TP63 | 15 | 6 | 17758 | 2588 |
SERPINB5,PCNA,TP53I3,FDXR,FAS,BAX |
| 1.463e-02 | -4.22 | RODRIGUES_THYROID_CARCINOMA_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_UP | 15 | 6 | 17758 | 2588 |
FAM89A,FAM195A,TMEM64,SLC16A6,ECI1,TMEM133 |
| 1.463e-02 | -4.22 | BIOCARTA_HSP27_PATHWAY | MSigDB lists | BIOCARTA_HSP27_PATHWAY | 15 | 6 | 17758 | 2588 |
MAPKAPK2,CASP3,MAPKAPK3,HSPB1,CASP9,FAS |
| 1.463e-02 | -4.22 | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_UP | 195 | 40 | 17758 | 2588 |
SPRED1,CDS2,ACVR1,IQGAP1,MAN1A2,ADO,PBX3,CNTROB,FAM91A1,SLC20A1,E2F7,PHF7,OXCT1,CTNNB1,PRICKLE3,GPC3,FAM20B,PAPSS1,SNX16,TRPC1,HSPA13,KLF9,STT3B,LRIF1,FAR1,CASD1,TIAM1,DDX59,SOAT1,LPGAT1,ITCH,AMFR,MGAT4B,KBTBD8,C2orf69,ERBB2IP,HSF4,DCK,CSTF2,CXorf56 |
| 1.463e-02 | -4.22 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP | 195 | 40 | 17758 | 2588 |
GSDMD,ZMAT1,AGRN,SLC41A1,TRAF2,ATP6V1E2,BLCAP,ADCK5,BAIAP3,SEPP1,TRIM68,AIP,NFAT5,ICAM1,APOBEC3B,LRRC45,GRHL1,PHTF1,HLA-C,MAP3K7,F2R,NEB,NAGA,PHKG2,MGAT5,P2RX4,LOC81691,KIAA0040,CDA,AKR1E2,TBC1D17,HTT,OTUD6B,SLC35B3,NR4A3,PNPLA6,CANT1,PGM2L1,CBX7,DIS3L |
| 1.463e-02 | -4.22 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_DN | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_DN | 195 | 40 | 17758 | 2588 |
FAM171B,GCAT,FAM129B,NDRG1,GNAL,CACNA2D2,GPSM2,TMPRSS4,SH2D4A,IER3,CALR,CCNA2,MGAT4A,RANBP1,KIF22,BUB1,STT3B,KIAA1841,ASPM,PBK,CDC20,STRADB,CCDC34,CDCA2,NUSAP1,TNS1,AURKB,CDC25C,SLC25A4,RND3,FAM114A1,KPNA2,CENPE,ITPKA,SGOL1,NCAPG2,CCNB2,UBE2C,RARG,MELK |
| 1.463e-02 | -4.22 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | 195 | 40 | 17758 | 2588 |
LAMP1,DNAJB2,TP53,ARL4C,GATA3,SELL,KCTD12,FAM101B,FAM46C,SIPA1L2,LMO4,ZFP36,SLC44A1,FOSB,SORL1,FAM102A,PIM1,RPGR,NR2C1,DUSP1,POU6F1,P2RX4,MBP,SNTB2,SLC11A2,TCF7,SESN1,FOS,RHOB,SOCS3,MYPOP,TAPBP,BTG1,ETS2,NR1D2,ARRB1,NFKBIZ,TOB1,FAM134B,ABCG1 |
| 1.463e-02 | -4.22 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | 195 | 40 | 17758 | 2588 |
CDS2,PINK1,POC1B,DNAJB2,SDC4,SUDS3,SORBS3,PKN1,FAM167A,PSIP1,TMEM63A,ADRBK1,FXYD5,C10orf54,KCTD3,EPHX1,P2RX4,SUN2,ATL1,TGIF1,MBP,CXXC5,PLEKHA6,ADCK3,SNTB2,ARHGDIB,SAV1,ARHGAP24,PLCG1,PHLPP2,WFS1,SLC25A40,SLC4A3,DTX4,PRDM5,HS3ST3B1,ARF6,WBSCR27,TBC1D4,KLF7 |
| 1.463e-02 | -4.22 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | 195 | 40 | 17758 | 2588 |
TXN,TRIP10,AASS,DNAJC3,NDRG1,GMPR,TESK2,CUL1,DUSP5,ICAM1,NRP2,IER3,TYMP,CDH1,PAIP2B,RRBP1,ANKRD12,TRIM21,PDE4D,PIM1,DUSP1,PLSCR1,TNIP1,PLAUR,RAPGEF2,LITAF,AK4,RNF19B,LHFPL2,LCP1,CYB5A,CD83,PLCH1,SERPINA1,WIPI1,FGFR2,RND3,DTX4,GEM,MAD2L1BP |
| 1.463e-02 | -4.22 | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN | 195 | 40 | 17758 | 2588 |
GRN,LGALS3,S100A11,CTSB,HEXB,ASAH1,KCTD12,NOTCH2,SIRPA,GNS,TNS3,APLP2,MGAT1,SLC16A6,PLCG2,CST3,CAPG,DAPK1,BCL6,MTMR11,PTPRE,SYK,CKAP4,QSOX1,GCA,MCTP1,TIMP2,SAT1,VAMP3,NPC2,SERPINA1,CORO1C,RAB31,NOD2,PPM1H,ARAP1,ZMIZ1,SLC31A2,SLC27A3,CD33 |
| 1.463e-02 | -4.22 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_UP | 195 | 40 | 17758 | 2588 |
PRSS8,RPS6KA1,FLOT1,CDIPT,FLT3,MNS1,EXT2,ECI1,LBR,CORO1B,B4GALNT1,RAC2,RGS3,PHTF1,DDHD2,RANBP1,SLC44A1,PCYOX1,SLC44A2,H2AFY,SLC12A2,ALDH3A2,SLC35A1,MAP3K3,HES1,KIF20A,SEPT6,SPATA13,CAPNS1,PIM3,FOS,SLC25A4,ATXN7L3,H1F0,ABCB1,AURKA,MRPS28,PLXND1,JAK3,SRSF9 |
| 1.463e-02 | -4.22 | GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN | 195 | 40 | 17758 | 2588 |
DDX58,SLC25A24,PARP12,CEP70,IBTK,ZCCHC24,BACE1,SOD2,EFHD2,HMGN3,RB1,IL6ST,PAPL,SRR,SGK3,DUSP10,OAS3,STK35,SNED1,GCC2,CTNNAL1,GRIN1,CALCRL,SRSF5,DUSP4,NFIX,SOX13,EDNRA,RND3,PLK2,STAT1,RAB11FIP1,PPP1CB,MAOA,NR4A2,ISOC1,AHR,CPPED1,JARID2,EHD1 |
| 1.463e-02 | -4.22 | nephron epithelium development | biological process | GO:0072009 | 97 | 23 | 16441 | 2455 |
HES1,LGR4,FMN1,IQGAP1,SOX9,DCHS1,GATA3,ILK,IRX3,BMP2,CTNNBIP1,PROM1,FAT4,CTNNB1,NPNT,GPC3,DLG1,SMO,PKD2,TACSTD2,SOX8,OSR1,ADAMTS16 |
| 1.464e-02 | -4.22 | positive regulation of mitotic nuclear division | biological process | GO:0045840 | 46 | 13 | 16441 | 2455 |
PLK1,RB1,INSR,DLGAP5,IGF1R,PTEN,CDCA5,RGCC,AURKA,NUSAP1,PDGFB,UBE2C,ESPL1 |
| 1.467e-02 | -4.22 | ubiquitin-dependent protein catabolic process | biological process | GO:0006511 | 448 | 84 | 16441 | 2455 |
FAF2,PSME2,CUL4B,PTTG1,FBXO2,CUL1,UBE2Z,PSME1,MVB12B,CCNB1,HDAC6,RAD23A,PSMD1,KIF14,PSMC2,PLK1,SIRT1,SEC61B,ERLEC1,FBXL16,ITCH,USP18,RNF11,CDC20,VPS4B,RNF165,AURKB,CCNF,CBL,RNF19B,CDK1,VCP,TRIM9,DNAJC10,PSMD3,WFS1,WWTR1,AREL1,PSMC1,HSP90B1,PINK1,JKAMP,DNAJB2,CIT,PSMD7,PSMD10,ZNRF3,FBXO6,DNAJB9,WWP2,RNF128,FBXO7,NEK2,UBE2J1,FBXL14,WWP1,USP38,USP1,STT3B,ZRANB1,MYLIP,PSMA5,UFD1L,PSMB4,USP31,AMFR,NUB1,UBE2A,FBXO8,FBXO9,TP53INP2,PSMA4,FBXO10,USP6,UBE2D2,AURKA,ARRB1,YOD1,NDFIP1,UBE2C,RNF146,USP16,FBXW5,USP43 |
| 1.469e-02 | -4.22 | CCAWYNNGAAR_UNKNOWN | MSigDB lists | CCAWYNNGAAR_UNKNOWN | 138 | 30 | 17758 | 2588 |
UFD1L,SPC25,MACC1,ARL4C,TESK2,RAB6A,CCNB1,LDB2,KDM3A,RHOB,MECOM,FOXP2,PCNA,ZNRF2,PRCP,IL6ST,MFSD2A,DNM2,BCL6,PLK4,CKS1B,AKR1B1,ARVCF,CTNND1,RFX5,MYH14,PPP2R5D,NR3C2,TSPAN33,NXT2 |
| 1.469e-02 | -4.22 | WHITFIELD_CELL_CYCLE_M_G1 | MSigDB lists | WHITFIELD_CELL_CYCLE_M_G1 | 138 | 30 | 17758 | 2588 |
CEP70,VANGL1,FOPNL,PBK,PTTG1,HMG20B,GDF15,MORF4L2,ANTXR1,NCS1,RHEB,PDGFA,DCTN6,KIF5B,NCOA3,MSL1,ST5,GATA2,PLK2,PRC1,OPN3,IFIT1,SLC39A10,PLIN3,NUP37,LRIF1,BTBD3,AFAP1,LNP1,RAD21 |
| 1.469e-02 | -4.22 | MORF_PRKAR1A | MSigDB lists | MORF_PRKAR1A | 138 | 30 | 17758 | 2588 |
LAMP2,PIGC,SOD1,PSMB4,UGP2,PSMD7,ARFGEF1,UBE2A,MORF4L2,RAB6A,COX6C,MYL12A,BCAP31,PSMA4,ABR,DNPEP,SETD3,TMBIM6,GLB1,RPN2,MDH1,PPP1CA,MYL12B,SLC35A1,EEF1D,TMED2,KDELR1,RAD21,PRKAR1A,EBAG9 |
| 1.471e-02 | -4.22 | central_nervous_system-brain-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma_Grade_III | 260 | 51 | 17775 | 2585 |
EXPH5,GLIS3,ILDR1,USH1C,ARHGEF11,RET,TP53,ERBB2,PLXNA1,NOTCH2,SBF1,NEO1,CDKN2C,RB1,MUC16,CTNNB1,DNAH6,PTEN,OSBPL3,AIM1,MSH2,PIK3CA,PCYOX1,CACNA1D,PANX2,PHKA2,MYT1,NEB,RIMS2,MSH6,FARP2,AKT1,WNT10B,PIK3R1,TEP1,RAB3IP,HEATR5A,TANC1,IDH1,MAP3K6,GNA11,EGFR,USP6,GNAS,SHROOM3,SLC9A6,NAB2,TANC2,AKNA,UNC5B,PKD1L2 |
| 1.474e-02 | -4.22 | thyroid-carcinoma-anaplastic_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-anaplastic_carcinoma | 886 | 152 | 17775 | 2585 |
TRIM2,TRIM24,PNPLA2,RET,SMARCAL1,GATA3,PLXNA1,KIF26A,BARD1,TRIM68,CDKN2C,NUP210,CTNNB1,ZCCHC12,CDKL5,P4HB,RGS3,MKRN3,IL6ST,SLC46A1,PIK3CA,KCNS3,POF1B,IRF2,SUN3,IQCD,PIK3CD,TLN2,TIAM1,ZNF462,CELSR2,SERTAD4,RGAG1,EZR,TNS1,IDH1,LHFPL2,SPNS3,DPYSL3,DZIP1L,TRIM47,ATP7B,MADD,HDAC1,RNASEL,UNC5B,MRC2,INPPL1,PEX6,STRN4,AKAP17A,RACGAP1,RAVER2,C9orf69,WDFY1,ITGA3,PFKL,PIK3AP1,OCRL,SLC30A6,TMEM51,CACNA1D,MOXD1,GAD1,TTLL1,PLEKHA6,PCDH1,DCHS1,VWA1,EIF2AK1,MEST,GNA11,EGFR,PRX,GNAS,MAGED2,SLC6A6,PLEKHH2,ETS2,NAB2,SFMBT1,NR4A2,ZDBF2,GDF11,HOOK1,RPS6KA3,CCDC109B,CERCAM,IQGAP1,TP53,ZMYND10,MICALL2,KTN1,ST5,MUC16,CDH1,TACC2,FRYL,NOTCH3,DLG3,PHKA2,MYT1,ATG4D,AKT1,PTPRU,CAPN6,SYNE2,CCSAP,TEP1,TANC1,CBL,TSPAN18,SPTBN5,IRF7,ARHGAP4,B4GALT3,PRKAR1A,FARP1,ARHGEF7,SCD5,NKRF,DNAH3,SRPX2,PNPLA5,NEO1,PDIA4,FOXP2,SLC25A45,PTEN,H2AFY,ABCD1,CLIP2,IGDCC4,NFE2L3,FBLN5,B3GNT2,CTNNAL1,PIK3R1,LRRC66,TTC7A,COL7A1,AKAP3,YES1,SNTB1,DDX23,KLHL2,FAT4,CCDC6,DHRS2,CSGALNACT1,PPM1H,TBC1D4 |
| 1.474e-02 | -4.22 | anaplastic_carcinoma | COSMIC cancer mutations | anaplastic_carcinoma | 886 | 152 | 17775 | 2585 |
TRIM2,TRIM24,PNPLA2,RET,SMARCAL1,GATA3,PLXNA1,BARD1,KIF26A,TRIM68,CDKN2C,NUP210,CTNNB1,P4HB,CDKL5,ZCCHC12,RGS3,MKRN3,IL6ST,SLC46A1,KCNS3,PIK3CA,POF1B,IRF2,IQCD,SUN3,PIK3CD,TLN2,TIAM1,ZNF462,CELSR2,SERTAD4,RGAG1,EZR,TNS1,IDH1,LHFPL2,SPNS3,DZIP1L,DPYSL3,TRIM47,ATP7B,MADD,HDAC1,RNASEL,UNC5B,MRC2,INPPL1,PEX6,STRN4,AKAP17A,RACGAP1,RAVER2,C9orf69,WDFY1,ITGA3,PIK3AP1,PFKL,OCRL,SLC30A6,TMEM51,CACNA1D,MOXD1,GAD1,TTLL1,PCDH1,PLEKHA6,DCHS1,VWA1,EIF2AK1,MEST,GNA11,EGFR,PRX,GNAS,MAGED2,PLEKHH2,SLC6A6,ETS2,NAB2,SFMBT1,NR4A2,GDF11,ZDBF2,HOOK1,RPS6KA3,CCDC109B,IQGAP1,CERCAM,TP53,ZMYND10,MICALL2,KTN1,MUC16,ST5,CDH1,TACC2,FRYL,NOTCH3,DLG3,PHKA2,MYT1,ATG4D,AKT1,PTPRU,CAPN6,SYNE2,CCSAP,TEP1,CBL,TANC1,TSPAN18,IRF7,SPTBN5,ARHGAP4,B4GALT3,PRKAR1A,FARP1,SCD5,ARHGEF7,NKRF,DNAH3,SRPX2,PNPLA5,PDIA4,NEO1,FOXP2,SLC25A45,PTEN,H2AFY,ABCD1,CLIP2,IGDCC4,NFE2L3,FBLN5,B3GNT2,CTNNAL1,PIK3R1,LRRC66,TTC7A,COL7A1,YES1,AKAP3,SNTB1,DDX23,KLHL2,FAT4,CCDC6,DHRS2,CSGALNACT1,PPM1H,TBC1D4 |
| 1.474e-02 | -4.22 | MOTOR_ACTIVITY | MSigDB lists | MOTOR_ACTIVITY | 28 | 9 | 17758 | 2588 |
KIF5B,GRIN1,KIF23,KIF22,KIF2C,CENPE,KIF11,APPBP2,DNAI1 |
| 1.474e-02 | -4.22 | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | 28 | 9 | 17758 | 2588 |
IRS2,SOAT1,SPP1,AK7,SAT1,RAB20,EGLN3,SERPINB1,KLF7 |
| 1.474e-02 | -4.22 | NGUYEN_NOTCH1_TARGETS_UP | MSigDB lists | NGUYEN_NOTCH1_TARGETS_UP | 28 | 9 | 17758 | 2588 |
NQO1,SLC4A3,FLOT1,HDAC1,COL18A1,PSMD10,ITGAV,F2R,S100A13 |
| 1.474e-02 | -4.22 | GNF2_SNRK | MSigDB lists | GNF2_SNRK | 28 | 9 | 17758 | 2588 |
HECA,ARHGEF3,MSL1,JAK1,SEMA4D,STK38,BTN3A2,BTN3A1,RASGRP1 |
| 1.474e-02 | -4.22 | PID_WNT_SIGNALING_PATHWAY | MSigDB lists | PID_WNT_SIGNALING_PATHWAY | 28 | 9 | 17758 | 2588 |
CTHRC1,KREMEN2,FZD4,RYK,WNT3A,FZD5,KREMEN1,FZD6,FZD7 |
| 1.475e-02 | -4.22 | negative regulation of microtubule depolymerization | biological process | GO:0007026 | 23 | 8 | 16441 | 2455 |
GAS2L1,MID1IP1,CKAP2,AURKA,AURKB,HDAC6,CCNB1,APC2 |
| 1.475e-02 | -4.22 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_III | 116 | 26 | 17775 | 2585 |
SCN5A,ACVR1,ASXL1,PIK3R1,ARFGEF1,TP53,FTH1,NUCB2,TANC1,IDH1,PHLDA1,ULK2,CDKN2C,ENDOD1,DOPEY2,CDCA4,PTEN,TUBGCP6,ABCB1,PIK3CA,TUBG1,TAGLN2,B4GALT3,NEB,ABCC1,IGSF3 |
| 1.483e-02 | -4.21 | V$MYB_Q6 | MSigDB lists | V$MYB_Q6 | 236 | 47 | 17758 | 2588 |
IER5L,LTBP1,CDK17,PPP4R4,FAF2,GCAT,CDCA3,NOTCH2,SDC1,REPS1,SLC9A7,CDK14,ZYX,MDM1,SESN3,PHF7,ADRBK1,SLC16A6,DACT1,TMEM62,FRAS1,TOX2,FBXL14,FAM63A,TRPC1,CITED2,DLG3,DLGAP1,RHOA,TFAP2C,PRICKLE1,C12orf65,NKAIN1,TYSND1,GNAS,ONECUT1,FYN,ZNF367,WFS1,AGBL5,KLF5,RCAN2,OSR1,NR3C2,RARG,JARID2,PHC1 |
| 1.483e-02 | -4.21 | ATPASE_E1_E2 | prosite domains | PS00154 | 36 | 11 | 11866 | 1802 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP13A3,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 1.483e-02 | -4.21 | PFKP (phosphofructokinase, platelet) | protein interactions | 5214 | 67 | 18 | 16036 | 2547 |
FAF2,TUBB4B,CDA,PYGL,MAPK4,SAMD9,FBXO6,PKM,MCFD2,ILK,HDAC6,PCBP1,EGFR,PLCG1,PFKL,VAT1,DMWD,CD81 |
| 1.483e-02 | -4.21 | ALK (anaplastic lymphoma receptor tyrosine kinase) | protein interactions | 238 | 67 | 18 | 16036 | 2547 |
TUBB4B,PIK3R1,EPHA1,RAD17,BCAR1,MDK,PLCG1,FLII,PDLIM3,SHC3,CORO1C,MYLK,IRF7,MAP3K5,PLCB2,JAK3,ZC3HC1,SOCS5 |
| 1.483e-02 | -4.21 | STIM2 (stromal interaction molecule 2) | protein interactions | 57620 | 7 | 4 | 16036 | 2547 |
PRKAA2,STIM1,CALM1,HEXB |
| 1.483e-02 | -4.21 | RPS4Y1 (ribosomal protein S4, Y-linked 1) | protein interactions | 6192 | 7 | 4 | 16036 | 2547 |
IGSF8,CD81,CALM1,ICAM1 |
| 1.483e-02 | -4.21 | BACE2 (beta-site APP-cleaving enzyme 2) | protein interactions | 25825 | 7 | 4 | 16036 | 2547 |
ATP1B3,GGA1,HLA-E,TMEM30A |
| 1.483e-02 | -4.21 | TUBA1A (tubulin, alpha 1a) | protein interactions | 404053 | 7 | 4 | 16036 | 2547 |
DPYSL5,DPYSL4,DPYSL2,DPYSL3 |
| 1.483e-02 | -4.21 | LPAR2 (lysophosphatidic acid receptor 2) | protein interactions | 9170 | 7 | 4 | 16036 | 2547 |
ARHGEF11,SIVA1,SLC9A3R2,BCL6 |
| 1.483e-02 | -4.21 | AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) | protein interactions | 116986 | 7 | 4 | 16036 | 2547 |
PLCG1,MPRIP,NF2,PIK3R1 |
| 1.483e-02 | -4.21 | Racgap1 (Rac GTPase-activating protein 1) | protein interactions | 26934 | 7 | 4 | 16036 | 2547 |
KIF23,RACGAP1,SH3KBP1,PRC1 |
| 1.483e-02 | -4.21 | ZWILCH (zwilch kinetochore protein) | protein interactions | 55055 | 7 | 4 | 16036 | 2547 |
SNX8,KNTC1,ANLN,UBE2A |
| 1.483e-02 | -4.21 | SLC12A6 (solute carrier family 12 (potassium/chloride transporter), member 6) | protein interactions | 9990 | 7 | 4 | 16036 | 2547 |
STK39,LGALS3,FAM189A2,LGALS8 |
| 1.483e-02 | -4.21 | C19orf60 (chromosome 19 open reading frame 60) | protein interactions | 55049 | 7 | 4 | 16036 | 2547 |
PIAS3,SMN1,MDFI,PSMD7 |
| 1.483e-02 | -4.21 | AKIP1 (A kinase (PRKA) interacting protein 1) | protein interactions | 56672 | 7 | 4 | 16036 | 2547 |
SIRT1,MAPK13,PRKACA,BARD1 |
| 1.483e-02 | -4.21 | HIST2H2BF (histone cluster 2, H2bf) | protein interactions | 440689 | 7 | 4 | 16036 | 2547 |
IGSF8,CD81,SPRTN,ICAM1 |
| 1.483e-02 | -4.21 | SLC27A3 (solute carrier family 27 (fatty acid transporter), member 3) | protein interactions | 11000 | 7 | 4 | 16036 | 2547 |
ERLEC1,FAM189A2,SPINT2,MCOLN3 |
| 1.483e-02 | -4.21 | FCER2 (Fc fragment of IgE, low affinity II, receptor for (CD23)) | protein interactions | 2208 | 7 | 4 | 16036 | 2547 |
CR2,FYN,PARP14,STAT6 |
| 1.483e-02 | -4.21 | PTCRA (pre T-cell antigen receptor alpha) | protein interactions | 171558 | 7 | 4 | 16036 | 2547 |
NOTCH3,HDGFRP2,RHBDL3,VCP |
| 1.483e-02 | -4.21 | RCOR2 (REST corepressor 2) | protein interactions | 283248 | 7 | 4 | 16036 | 2547 |
HDAC1,HMG20B,CTBP1,HDAC11 |
| 1.483e-02 | -4.21 | LAT2 (linker for activation of T-cells family member 2) | protein interactions | 7462 | 7 | 4 | 16036 | 2547 |
PLCG1,CBL,GAB1,PLCG2 |
| 1.483e-02 | -4.21 | SPRY4 (sprouty RTK signaling antagonist 4) | protein interactions | 81848 | 7 | 4 | 16036 | 2547 |
SPRY4,CBL,TESK1,SPRY2 |
| 1.483e-02 | -4.21 | SLC26A2 (solute carrier family 26 (anion exchanger), member 2) | protein interactions | 1836 | 7 | 4 | 16036 | 2547 |
LGALS3,FAM189A2,LGALS8,MGAT4B |
| 1.485e-02 | -4.21 | serine/threonine protein kinase complex | cellular component | GO:1902554 | 67 | 17 | 17570 | 2579 |
PRKAA2,ACVR1,ACVR1C,NUAK1,PRKAA1,TGFBR1,PRKAR2B,PRKACA,PRKAG2,PRDX3,GTF2F2,CAB39,ERCC2,PHKA2,MAP3K7,PHKG2,PRKAR1A |
| 1.486e-02 | -4.21 | Activation of NMDA receptor upon glutamate binding and postsynaptic events | REACTOME pathways | R-HSA-442755 | 41 | 12 | 8202 | 1235 |
CALM2,RASGRF1,RPS6KA2,CAMKK1,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D,PRKACA,RPS6KA3,CAMK2G |
| 1.489e-02 | -4.21 | KAYO_CALORIE_RESTRICTION_MUSCLE_UP | MSigDB lists | KAYO_CALORIE_RESTRICTION_MUSCLE_UP | 94 | 22 | 17758 | 2588 |
CCNI,SLC2A4,HSPG2,S100A11,S100A4,RASA2,CALB2,EMP3,SCRIB,RNF113A,FAS,SNTA1,ITGB8,PAFAH1B3,LIMK1,NR4A3,BCL6,RYK,VAT1,MTMR11,TOB1,CKAP4 |
| 1.489e-02 | -4.21 | YGTCCTTGR_UNKNOWN | MSigDB lists | YGTCCTTGR_UNKNOWN | 94 | 22 | 17758 | 2588 |
ARAP2,KCNAB3,TRIM2,THRA,FHL2,SEPT4,PRKACA,SNTA1,CXXC4,SYT7,STIM1,PPP2R4,MANF,SYT13,TMEM8B,ANO4,CITED2,ARMCX6,NDUFA12,CBX4,IGSF3,SOCS5 |
| 1.489e-02 | -4.21 | MODULE_169 | MSigDB lists | MODULE_169 | 94 | 22 | 17758 | 2588 |
TXN,IL15RA,CRIP2,BIK,CR2,PRKAR2B,HEATR5A,TRIB2,ASB13,FOS,TSPAN7,STK17A,IER3,TNS3,BMP7,BCL6,DAPK1,SORL1,SLC39A10,MYBL1,AHR,ABCC1 |
| 1.490e-02 | -4.21 | CXCR4 (chemokine (C-X-C motif) receptor 4) | protein interactions | 7852 | 39 | 12 | 16036 | 2547 |
HLA-B,ST13,JAK1,P4HB,ITCH,SDC4,STAT1,MYBL2,JAK3,ADRBK2,ATP13A2,SOCS3 |
| 1.490e-02 | -4.21 | THOP1 (thimet oligopeptidase 1) | protein interactions | 7064 | 39 | 12 | 16036 | 2547 |
IDE,OXCT1,UAP1,DCK,TRAF2,SYNE2,CALM1,TTC39C,IDH1,PRKACA,EGFR,PLS3 |
| 1.490e-02 | -4.21 | GMNN (geminin, DNA replication inhibitor) | protein interactions | 51053 | 39 | 12 | 16036 | 2547 |
CASP3,SMARCA2,CCNA2,CDH1,HOXB7,HDAC11,CDC20,AURKA,PNKD,CDK1,ARNT,PHC1 |
| 1.492e-02 | -4.20 | Stabilization and expansion of the E-cadherin adherens junction | Pathway Interaction DB | ecadherin_stabilization_pathway | 40 | 15 | 2227 | 480 |
CAMSAP3,ZYX,RHOA,VASP,IGF1R,CDH1,CTNNB1,PVRL2,PLEKHA7,CTNND1,EFNA1,NCKAP1,CYFIP2,ARF6,EGFR |
| 1.495e-02 | -4.20 | organelle lumen | cellular component | GO:0043233 | 4169 | 656 | 17570 | 2579 |
TRIM24,ADD1,IBTK,AASS,MRPS15,DNAJC3,HEXB,XIAP,SMARCAL1,CCNO,DHX8,TGOLN2,MORF4L2,SYTL4,DPP8,BARD1,PHF1,TP73,NPM2,CALM2,DAPK2,WEE1,PSMD1,RGS12,MUC4,UBE2T,TUBG1,PPP1CA,ACOX2,WBP4,ERAP2,SMARCA2,TNIP1,SPRTN,MTRF1L,TFAP2C,LOXL2,GINS4,COL12A1,LIMK1,HDAC1,MRPS28,RNASEL,PDPR,ANXA11,NXT2,ALDH6A1,GGA1,NUAK1,SOX9,FAM21C,LMNA,GNS,FLII,DNPEP,ZCCHC17,ATP5H,NEK2,FBXL14,CADPS2,USP1,MYDGF,MAPK7,C9orf72,MCCC2,REC8,UFD1L,KIF20A,MAPKAPK3,SALL4,STAT4,PYM1,ERO1A,FHL2,MYBL2,KIF20B,SRSF5,ELK1,ILK,TP53INP2,PSMA4,DCP2,SCARB2,NCOA3,ETS2,HTT,SETD3,ITPR1,AURKA,GDF11,CFAP20,CBX5,RPS6KA3,GRHL2,ACTR8,ETNK1,TESK2,PKP2,MAPK4,PRKACA,CCND1,RCN1,MUC16,SP100,DACT1,ARL4D,CDKN2D,MYT1,ETV4,RNF169,COL6A2,NRBF2,AGPS,SYNE2,HTATIP2,CDCA2,NUSAP1,RAB38,GTF2A2,PEX5,CCNB3,WWTR1,PDXK,RGS14,GEN1,ARNT,MAPK12,TAOK2,HSP90B1,GCAT,BACE1,ESRP1,DCAF7,SDC4,HABP4,PDIA3,GMCL1,CTSZ,PKN1,TMA16,ETS1,NFAT5,PDIA4,NEO1,CTNNBIP1,DTX3L,ZFX,ADD3,CTSC,ARSG,ANKS1B,GPC3,FAM20B,FDXR,ECI2,MAPK11,AK3,RAG1,TMX1,MED22,CRTAP,PARP9,ACBD5,PLSCR1,BCL9,UBE2A,AK4,RAB11FIP2,ATXN7L3,NR1D2,NR4A3,HMGA1,CMPK2,NUP37,USF2,SRSF9,FOXA1,ACOT7,PHC1,AGRN,EPAS1,CUL4B,SUDS3,ARFGEF1,MCCC1,NDC80,LMCD1,NDRG2,DNAJB11,NENF,HDAC6,PDGFB,SDC1,FANCI,PCNA,RPS6KA2,CTNNB1,P4HB,PSMC2,SLC44A1,DUSP10,SMAGP,PLK1,THRB,PCGF5,ING1,STAU2,CBX6,C12orf65,EZR,ERP44,KLK6,EAF2,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,OPTN,KDM4D,MSL1,KLF12,MAP2,P4HA2,ZNF367,KPNA2,MAFF,PRKAA2,RUNX2,HJURP,PSMD7,ASAH1,RACGAP1,RB1,DAZAP1,TIMP1,GATA2,PAK2,MDFIC,FAR2,WNT3A,PSMA5,MRPS33,SPATA13,SCRIB,TCF7,PDK3,G2E3,SMN1,CDK5R1,MAPKAPK2,EPN3,H1F0,COL13A1,P4HA3,ZDHHC7,AKIP1,CCNB2,CTBP1,USP43,RAD21,NF2,HOXB7,UPF3B,FOXM1,P3H2,TP53,RHPN2,CCNL1,BAHD1,PCBP1,SDF4,PER2,TTC21B,PDGFA,KMT5C,TACC2,PLK4,NOTCH3,OAS3,MINPP1,EGLN3,FAR1,CTDSP2,GM2A,SIRT1,PPIF,ERLEC1,TCEB2,AKT1,FIGNL1,CDC20,SERTAD3,DAG1,ATP13A2,DNAJC10,PTGS2,IDE,RBL1,PSMD3,STK38,XRCC3,IRF7,LTA4H,CTDSP1,GSDMD,COL9A3,CMAS,PACSIN2,GOLIM4,CD63,TAB3,CTSB,BLVRB,MCTP2,SWI5,CDCA8,ERI2,ERCC6L,PSMD10,GTF3A,NKRF,HMGN3,CRABP2,AIP,DNAJB9,H1FX,GTF2F2,TFAP2A,FAM63A,SGK1,BUB1,ALDH7A1,HMGCL,KLF9,HEXIM2,CAMK2G,HES1,PSMB4,HMGN5,NR3C1,GUSB,PLAUR,LITAF,PPARA,MAML2,COL7A1,BCAR1,DDX23,FUCA1,SERPINA1,NEIL3,CDCA7L,NMI,FGF18,E2F1,PGRMC1,SH3BGRL2,ACADM,UBE2C,HIPK3,ZBTB33,DIS3L,GAA,PNISR,TXN,HSPG2,SSH1,FAM129B,GATA3,CUL1,PSME1,CCNB1,OAT,SEPT4,CENPN,HELZ2,RGS3,POLL,IRF2,ZBTB18,LAMP2,LOC81691,CDYL,PIF1,AURKB,SLC25A5,PRIM1,PPP2R4,FAM110C,DLAT,RECQL,DGKQ,KIF23,AKAP17A,NOTCH2,PSIP1,BMP2K,MECOM,SH3RF2,CALR,SNX18,BDH1,MSH2,CTSD,EEF1D,GID8,PRODH,DDB2,PMPCB,CALM1,WHSC1,VEZT,KDM3A,JADE2,NFIB,PRKAG2,FAM64A,WDR19,APPL2,PIAS2,SFMBT1,CABIN1,NR4A2,ZBTB34,NRBP1,IRF1,ELK4,SPRED1,CEP70,TRIP10,THRA,RPS6KA1,CCDC110,SUZ12,CERCAM,BCL2L1,FLT3,CYHR1,CCNA2,TNPO2,CDKN1B,RNASEH2A,LGMN,MED30,NR2C1,ATG4D,CDKN2AIP,TMEM43,FOXJ2,LYRM1,UTRN,TEP1,PKMYT1,PYGO1,RAD17,ITPR3,H2AFV,ATP10D,SP4,NIN,CEP162,ZNF641,CFAP45,ACAD10,STAT1,PPP1CB,KLF5,NR3C2,CBX7,MRPS9,DEPDC1,CENPI,CBLL1,SPR,TEAD3,AKIRIN1,OXCT1,PHF7,PPP1R10,PTEN,PRC1,ERCC2,MAP3K7,CITED2,CNPY3,GFI1,MSH6,NCOA2,SMC4,PDGFC,TGIF1,PCCB,CASK,ALDH2,PAPD7,FURIN,DIAPH2,FOS,ARSK,CPTP,CRTC2,ACADSB,PRDX3,FGFR2,CSTF2,ERAP1,ARSB,NCAPG2,JARID2,CCNC,CASP3,CRYM,CPT2,UBE2Z,MPP5,TAF6L,ERP29,ECI1,TRIM68,TSEN34,CHPF,GRHL1,ZCCHC12,CDKL5,SIVA1,PHTF1,CAPG,AKR1B1,ANKRD12,ASH2L,NFU1,STK35,SOD1,CENPA,TRIM8,CXXC5,ASXL1,LAP3,MRPS18A,MRPS36,TCN2,NEIL1,GPRC5B,HPSE,TDRD7,TRIM45,IARS2,GLA,PPP2R5D,PSMC1,NR2C2,PCSK5,PPP1R12A,ETV5,CALM3,PM20D2,ADAMTSL4,DUSP5,CES2,COL6A1,SRP54,ZRANB1,ACAD8,LRIF1,ETV7,ELK3,OXR1,HMG20B,PDIK1L,EGFR,SOX13,FECH,NUDT16,UAP1,UTP14C,CDCA5,PAPD5,CTSA,RARG,COL16A1,CCNE2,SORBS1,PAX6,IL15,PSME2,HDAC11,PDIA5,SOD2,COL18A1,MORC4,PHLDA1,SAP130,LRRC45,SETDB2,ETHE1,NFKB2,PDIA6,HSPA2,UPF3A,TAF5,MRPS35,ERBB2IP,SNAPC2,DUSP4,FANCE,CDC25C,PDHX,JADE1,HSF4,ALDH5A1,STAT6,PEX2,TLE1,SGOL1,CBX4,KDELC2,GLIS3,SH3D19,COL4A5,INTS8,HDAC9,IRF2BPL,TOP2A,CARD8,TAF1B,LLGL2,GALNS,TOX2,CKS1B,H2AFY,SUN2,CENPC,NR4A1,SYBU,RC3H2,OGDHL,RUNX3,POLD3,MPV17L2,SPAG1,CTSL,CASP7,TRIM69,HNRNPH2,DHRS2,CTSV,UBE2D2,TADA2B,ARRB1,GLB1,HOXB13,ZMIZ1,AHR,ABCG1 |
| 1.497e-02 | -4.20 | PID_BETA_CATENIN_NUC_PATHWAY | MSigDB lists | PID_BETA_CATENIN_NUC_PATHWAY | 78 | 19 | 17758 | 2588 |
SALL4,BCL9,CUL1,AES,TCF7,CTNNBIP1,CCND1,PITX2,CDH1,CTNNB1,ZCCHC12,CYR61,MITF,TLE1,HDAC1,MDFIC,CTBP1,NCOA2,SP5 |
| 1.497e-02 | -4.20 | REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | REGULATION_OF_HYDROLASE_ACTIVITY | 78 | 19 | 17758 | 2588 |
RALBP1,CASP9,TP53,EGFR,VCP,EDNRA,TSC1,CARD8,PPP2R4,STAT1,BAX,ARAP1,FGD6,AIFM3,PLCB2,CDKN2D,F2R,IFI6,FGD1 |
| 1.497e-02 | -4.20 | SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP | MSigDB lists | SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP | 78 | 19 | 17758 | 2588 |
TXN,ST13,TACC1,MICB,CASP9,SOD2,UBE2A,CUL1,CASP4,HSF2,PCNA,JAK1,PRDX3,ITPR1,UBE2D2,PIK3CA,MAP3K5,ESPL1,UPF3A |
| 1.497e-02 | -4.20 | KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP | MSigDB lists | KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP | 127 | 28 | 17758 | 2588 |
FAM169A,SAT1,BIK,FBXO2,CDA,HTATIP2,IL18,GDF15,ISYNA1,PLA2G16,MAP1LC3B,S100A2,DNAJB9,MYO5C,FUCA1,FAAH,FGD6,CD70,SERPINI1,IRF7,TACSTD2,LGMN,TSPAN1,F2RL1,HSPA2,TOB1,IL1RAP,NXT2 |
| 1.498e-02 | -4.20 | regulation of G2/M transition of mitotic cell cycle | biological process | GO:0010389 | 51 | 14 | 16441 | 2455 |
CCND1,CCNA2,CCNB3,WNT10B,KIF14,VPS4B,PRKCQ,FHL1,CDK1,MIIP,HSPA2,FANCI,PKIA,IER3 |
| 1.499e-02 | -4.20 | GoLoco | smart domains | SM00390 | 7 | 4 | 9131 | 1455 |
GPSM2,RGS12,RGS14,RAP1GAP |
| 1.499e-02 | -4.20 | Hr1 | smart domains | SM00742 | 7 | 4 | 9131 | 1455 |
RHPN2,RTKN2,PKN1,RHPN1 |
| 1.499e-02 | -4.20 | GS | smart domains | SM00467 | 7 | 4 | 9131 | 1455 |
TGFBR1,ACVR1,ACVRL1,ACVR1C |
| 1.499e-02 | -4.20 | FERNANDEZ_BOUND_BY_MYC | MSigDB lists | FERNANDEZ_BOUND_BY_MYC | 178 | 37 | 17758 | 2588 |
PLA2G4A,SLC2A4,TXN,FOXM1,CD63,THRA,ITGA6,TGFBR1,GSTP1,LBR,SLC9A3R2,ICAM1,LMNA,PTEN,BAX,FUT1,IRF2,RNASEH2A,EPHX1,ALDH2,EIF5A2,CASP9,MYBL2,CR2,ELK1,ARF4,MAN2A2,FECH,INSR,ETS2,ACAD10,DCK,STAT6,NAB2,E2F1,ACADM,RPL22 |
| 1.499e-02 | -4.20 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN | 178 | 37 | 17758 | 2588 |
CCDC24,PPP1R2,GNAL,TDRKH,ZNRF3,LACTB2,BMP2K,SYTL2,PDGFA,OTUD1,RB1,SPIN4,PASK,TOX2,TMEM51,SGK1,CCDC82,MDFIC,PDE4D,CNOT6L,CLIP2,GCA,TGIF1,MBP,PLSCR1,TTC7A,PLS1,IFIT3,FAS,PTGS2,RIN3,ITPR1,PGM2L1,ARRB1,RELL1,HS3ST3B1,F2RL1 |
| 1.503e-02 | -4.20 | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN | MSigDB lists | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN | 733 | 128 | 17758 | 2588 |
FAM160B1,TAF6L,PLA2G16,OAT,SPSB1,CMTM6,ARHGEF10L,RGS12,PQLC2,NUP210,CTNNB1,ATRNL1,HYLS1,PPP1CA,RCAN3,RNF26,MYRIP,ODF2L,NEK4,TRIM8,LAP3,CASP9,RNF11,NBPF3,NKAIN1,ICMT,RNF19B,TRUB1,KDM4D,LRRC42,PI4K2B,WDR11,EIF4EBP2,RELL1,MIIP,DLAT,NR2C2,TBC1D1,RAB6A,HPCAL4,SSX2IP,ZCCHC17,RIMS3,TMEM51,SLAIN2,STT3B,ACAD8,ZMYM1,ZRANB1,HP1BP3,PAQR7,WHSC1,DPYSL4,PTPRF,DGAT2,PER3,ZNF502,CTBP1,COL16A1,AFAP1,FAM45A,SORBS1,AVPI1,ZSWIM5,RPS6KA1,CTDSPL,WDTC1,ABCG4,FTH1,SDF4,ATP6V0B,APLP2,RNF220,PPME1,FRYL,GLB1L2,ECE1,MINPP1,RNF169,SIRT1,TAF5,NRBF2,TMEM43,CLSTN1,BTBD19,CBL,ATP13A2,ZMPSTE24,EPHA10,DDOST,JAK1,PPP2R2D,FBLIM1,PINK1,JRKL,EFHD2,FBXO6,POMGNT1,VPS26A,SGPL1,CTNNBIP1,AKIRIN1,ADD3,PTEN,CCDC82,HMGCL,CPLX1,TRIM62,CAMK2G,B3GALT6,PGM1,RHOA,RAB3B,VAMP3,RUNX3,KIF11,POLD3,LEPR,BSDC1,BCL10,LDLRAP1,SYT7,RAB11FIP2,PRDX3,ARRB1,ZMIZ1,CPEB2,ACOT7 |
| 1.503e-02 | -4.20 | RHOGAP | prosite domains | PS50238 | 65 | 17 | 11866 | 1802 |
ARHGAP11A,ARAP3,ARAP2,RALBP1,PIK3R1,RACGAP1,ABR,SYDE2,ARHGAP35,ARHGAP24,ARHGAP42,SH3BP1,OCRL,FAM13B,ARAP1,ARHGAP4,STARD13 |
| 1.506e-02 | -4.20 | establishment of vesicle localization | biological process | GO:0051650 | 225 | 46 | 16441 | 2455 |
DOC2A,GRN,TRAPPC10,P2RX7,CTSZ,PLD2,SYTL4,SYTL2,KIF5B,AP1M2,CTNNB1,CTSC,DPYSL2,DNM2,CPLX1,LMAN1,TFG,RAB27B,PACSIN1,SYTL3,PPP6R1,TMED2,MYO5A,RASGRP1,SEC23A,RAB3B,SCRIB,KIF13A,COL7A1,MCFD2,BBS2,STX3,TRIM9,AP1AR,SERPINA1,FGFR2,SYT7,AREG,HTT,WIPI1,SYT13,NDE1,SHROOM2,TC2N,COPG1,SNPH |
| 1.506e-02 | -4.20 | positive regulation of lymphocyte activation | biological process | GO:0051251 | 248 | 50 | 16441 | 2455 |
LAMP1,DHPS,IL15,INPP5D,HLA-E,TRAF2,GATA3,IL18,EGR3,CD274,TNFSF9,EFNB1,HLA-A,CD46,IL6ST,PAK2,BCL6,PIK3CA,IGFBP2,MAP3K7,RAG1,WNT3A,SLC39A10,FLOT2,SYK,RASGRP1,MSH6,SOCS5,HES1,CD55,RHOA,RIPK2,AKT1,LGALS8,PIK3R1,WHSC1,PRKCQ,YES1,CD40,BCL10,CD83,IRS2,FYN,STAT6,AXL,NOD2,PPP2R3C,ICOSLG,CD81,JAK3 |
| 1.508e-02 | -4.19 | Schwann cell differentiation | biological process | GO:0014037 | 32 | 10 | 16441 | 2455 |
SOD1,FA2H,AKT1,NDRG1,NAB2,TFAP2A,MPP5,ERBB3,ILK,DAG1 |
| 1.508e-02 | -4.19 | metanephric nephron development | biological process | GO:0072210 | 32 | 10 | 16441 | 2455 |
HES1,CTNNB1,LGR4,FMN1,SOX9,SMO,PKD2,SOX8,OSR1,PDGFB |
| 1.508e-02 | -4.19 | negative regulation of JNK cascade | biological process | GO:0046329 | 32 | 10 | 16441 | 2455 |
TP73,PINK1,AKT1,DACT1,ITCH,DUSP10,F2RL1,GSTP1,HIPK3,MECOM |
| 1.508e-02 | -4.19 | reproductive behavior | biological process | GO:0019098 | 32 | 10 | 16441 | 2455 |
THRB,GRN,APLP2,SERPINE2,PTEN,THRA,HEXB,GRIN1,UBE2Q1,DRD1 |
| 1.508e-02 | -4.19 | regulation of protein oligomerization | biological process | GO:0032459 | 32 | 10 | 16441 | 2455 |
PEX5,IDE,BMF,DNM1L,BIK,TP53,BAX,SORL1,SNX9,FAS |
| 1.510e-02 | -4.19 | V$SRF_Q5_01 | MSigDB lists | V$SRF_Q5_01 | 207 | 42 | 17758 | 2588 |
MYL9,SLC2A4,PPP1R12A,SCOC,EGR3,GRK6,DUSP5,PPP2R3A,FOXP2,VASP,ITGB8,SLC16A6,CALD1,MITF,FOSB,TRIM3,CDKN1B,DUSP10,SGK1,DIXDC1,CITED2,DGKG,SUN2,DSTN,SERTAD4,ERBB2IP,KDM3A,FOS,ABR,LCP1,MAPKAPK2,TIMP3,SLC25A4,STX10,PELI2,CORO1C,MYLK,SLC4A3,CTNND1,ARF6,STARD13,ABCA1 |
| 1.513e-02 | -4.19 | SECRETION_BY_CELL | MSigDB lists | SECRETION_BY_CELL | 116 | 26 | 17758 | 2588 |
COG2,VAMP3,ARFGEF1,KIF1C,ERP44,AKAP3,SYTL4,BAIAP3,OPTN,PDIA4,NAPG,DOPEY2,KCNMB4,CARD8,SCG2,LMAN2L,STEAP2,NOD2,ARFGAP3,CPLX1,LTBP2,LMAN1,ARL4D,NRBP1,ABCA1,TMX1 |
| 1.513e-02 | -4.19 | chondrocyte differentiation | biological process | GO:0002062 | 61 | 16 | 16441 | 2455 |
RUNX2,WNT10B,HSPG2,SOX9,RUNX3,OSR2,NFIB,GPLD1,BMP2,NOV,IMPAD1,FGF18,OSR1,SHOX2,RARG,SULF2 |
| 1.513e-02 | -4.19 | IRE1-mediated unfolded protein response | biological process | GO:0036498 | 56 | 15 | 16441 | 2455 |
GFPT1,SEC61B,ADD1,WIPI1,SEC61G,DNAJC3,WFS1,PDIA5,KDELR3,DNAJB11,MYDGF,PDIA6,CTDSP2,DNAJB9,LMNA |
| 1.514e-02 | -4.19 | negative regulation of neuron differentiation | biological process | GO:0045665 | 174 | 37 | 16441 | 2455 |
SEMA6B,CIT,LRP4,EPHA4,SOX9,TP73,CALR,SPP1,PTEN,BMP7,KIAA0319,DIXDC1,NOTCH3,SEMA3G,WNT3A,NTN1,GFI1,ITM2C,SEMA3B,HES1,RHOA,ASPM,RAPGEF2,CDK5R1,ULK2,DPYSL3,IRX3,SEMA4D,PLK2,RAB29,GDF11,EFNA1,ARF6,SOX8,SEMA3A,NGEF,CTDSP1 |
| 1.514e-02 | -4.19 | CCS (copper chaperone for superoxide dismutase) | protein interactions | 9973 | 14 | 6 | 16036 | 2547 |
GOT1,SOD1,TXN,APBA1,SCRN2,XIAP |
| 1.514e-02 | -4.19 | DARS2 (aspartyl-tRNA synthetase 2, mitochondrial) | protein interactions | 55157 | 14 | 6 | 16036 | 2547 |
DPYSL5,FNTA,POR,PLAUR,ARHGEF26,DCP2 |
| 1.514e-02 | -4.19 | CAV2 (caveolin 2) | protein interactions | 858 | 14 | 6 | 16036 | 2547 |
PLD2,FLOT2,EGFR,RASA1,DRD1,GOLGB1 |
| 1.514e-02 | -4.19 | COLEC10 (collectin sub-family member 10 (C-type lectin)) | protein interactions | 10584 | 14 | 6 | 16036 | 2547 |
SOD1,TIMP3,NUCB2,CKAP4,DCP2,DNAJB9 |
| 1.514e-02 | -4.19 | EPHA8 (EPH receptor A8) | protein interactions | 2046 | 14 | 6 | 16036 | 2547 |
AK4,EFNA5,FYN,EFNA1,CBL,ANKS1B |
| 1.517e-02 | -4.19 | KLK11 (kallikrein related peptidase 11) | protein interactions | 11012 | 26 | 9 | 16036 | 2547 |
RB1,TGFBR3,FRAS1,ERAP1,LOXL2,TXNDC11,CHPT1,KIAA1147,TUBA4A |
| 1.517e-02 | -4.19 | SH3BP2 (SH3-domain binding protein 2) | protein interactions | 6452 | 26 | 9 | 16036 | 2547 |
PLCG1,FYN,PLCG2,ERBB2,CBL,FLT3,SYK,SH3KBP1,RNF146 |
| 1.517e-02 | -4.19 | HEXA (hexosaminidase A (alpha polypeptide)) | protein interactions | 3073 | 26 | 9 | 16036 | 2547 |
PCNA,PDCD10,EZR,AHCY,FBXO6,H2AFV,KTN1,GM2A,RAD23A |
| 1.517e-02 | -4.19 | SORL1 (sortilin-related receptor, L(DLR class) A repeats containing) | protein interactions | 6653 | 26 | 9 | 16036 | 2547 |
DYRK3,LGALS8,GGA1,FURIN,AURKA,CUL1,SP6,PPP1CA,FBXO6 |
| 1.517e-02 | -4.19 | TACC1 (transforming, acidic coiled-coil containing protein 1) | protein interactions | 6867 | 26 | 9 | 16036 | 2547 |
S100A11,HTT,TACC1,TDRD7,AURKA,AURKB,BARD1,SH2D4A,CKAP5 |
| 1.517e-02 | -4.19 | PCSK9 (proprotein convertase subtilisin/kexin type 9) | protein interactions | 255738 | 26 | 9 | 16036 | 2547 |
RCN1,DNAJC10,TRAF2,BACE1,PGRMC1,DNAJB11,CDIPT,HSPB1,PDIA4 |
| 1.518e-02 | -4.19 | BCAR1 (breast cancer anti-estrogen resistance 1) | protein interactions | 9564 | 72 | 19 | 16036 | 2547 |
CASP3,VPS11,INPPL1,ARMCX3,PTPRH,PIK3R1,KIF13A,TNS1,CBL,TSEN34,SH3KBP1,BCAR3,PTPRF,ZYX,FYN,SH2D3C,PLPP3,ITGAV,TUBA4A |
| 1.520e-02 | -4.19 | Prolactin Signaling Pathway | WikiPathways | WP2037 | 75 | 20 | 4455 | 729 |
CASP3,AKT1,PIK3R1,ERBB2,TEC,ELK1,CBL,FOS,SIRPA,SOCS3,PIAS3,IRS2,FYN,RPS6KA2,JAK1,NFKBIA,PIK3CA,STAT1,CTSD,IRF1 |
| 1.522e-02 | -4.19 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | 161 | 34 | 17758 | 2588 |
CCDC110,RASA2,SELL,CALM3,SNN,TRIB2,MERTK,PGAP1,NFAT5,CHST2,SCML1,ZDHHC21,CALM2,SESN3,CDH1,METTL7A,IL6ST,KLF3,WWP1,SLC39A10,LGMN,ALS2CL,ABCC1,CALM1,TCF7,PKMYT1,TXK,ATP1A1,SERTAD2,NGFRAP1,APPL2,GLCCI1,APBA2,KLF7 |
| 1.522e-02 | -4.19 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | 161 | 34 | 17758 | 2588 |
LTBP1,XYLT1,NDRG2,HOXB2,CHST2,ASPHD2,IL6ST,IL31RA,OPN3,IFIT1,OAS3,RAB27B,C12orf75,SLC45A3,LAMP3,MX1,USP18,FHL2,PRKAR2B,DUSP4,B3GALNT2,IFIT3,IRX3,PTGS2,HOXA9,ITGA7,STAT1,NRG1,GEM,CMPK2,AHR,IFI6,PRKAR1A,DENND5B |
| 1.525e-02 | -4.18 | ubiquitin protein ligase binding | molecular function | GO:0031625 | 255 | 51 | 16491 | 2452 |
SCN5A,FAF2,PINK1,GRIK2,TRAF2,JKAMP,CUL4B,TP53,CUL1,UBE2Z,ERBB2,TRIB2,HDAC6,PRKACA,SNX9,MAP1LC3B,FZD6,CALR,RB1,UBE2T,RALB,UBE2J1,TMBIM6,PDE4D,DLG3,BAG4,TCEB2,FZD4,UBE2A,PRKAR2B,CD40,SLC25A5,EGFR,VCP,GABARAPL1,BCL10,JAK1,DNM1L,WFS1,NFKBIA,TRIOBP,PIAS2,ARRB1,AURKA,YOD1,FZD5,PER3,TRAF5,UBE2C,TMEM173,PRKAR1A |
| 1.525e-02 | -4.18 | CHD3 (chromodomain helicase DNA binding protein 3) | protein interactions | 1107 | 143 | 33 | 16036 | 2547 |
LGR4,HABP4,TP53,FAM134A,TXNDC9,PSME1,ZNF219,BARD1,TP73,SLC27A6,TSPAN6,PLK4,BCL6,TWIST1,CTTN,LRIF1,CPE,METAP2,SIRT1,MX1,PHF20L1,SMARCA2,NR4A1,SAT1,MAN2A2,HTT,OTUD6B,NAB2,CSTF2,HDAC1,KPNA2,CTBP1,RAD21 |
| 1.528e-02 | -4.18 | positive regulation of cell activation | biological process | GO:0050867 | 283 | 56 | 16441 | 2455 |
LAMP1,DHPS,IL15,INPP5D,RPS6KA1,HLA-E,TRAF2,GATA3,IL18,EGR3,CD274,TNFSF9,EFNB1,HLA-A,CD46,CTGF,IL6ST,PAK2,BCL6,PIK3CA,IGFBP2,MAP3K7,RAG1,SLC39A10,WNT3A,FLOT2,SYK,RASGRP1,MSH6,SOCS5,HES1,CD55,RHOA,RIPK2,AKT1,LGALS8,DMTN,PIK3R1,WHSC1,PRKCQ,YES1,CD40,BCL10,CD83,IRS2,FYN,PVRL2,STAT6,AXL,NOD2,NR4A3,PPP2R3C,ICOSLG,CD81,JAK3,F2RL1 |
| 1.528e-02 | -4.18 | phosphatase activator activity | molecular function | GO:0019211 | 11 | 5 | 16491 | 2452 |
BMP2,CALM3,CALM2,CALM1,PPP2R4 |
| 1.528e-02 | -4.18 | diacylglycerol kinase activity | molecular function | GO:0004143 | 11 | 5 | 16491 | 2452 |
DGKH,DGKG,DGKE,DGKQ,DGKA |
| 1.528e-02 | -4.18 | ether hydrolase activity | molecular function | GO:0016803 | 11 | 5 | 16491 | 2452 |
LTA4H,TMEM86B,RNPEP,EPHX4,EPHX1 |
| 1.531e-02 | -4.18 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | 184 | 38 | 17758 | 2588 |
LASP1,MPZL1,MRPS15,ATP8A1,ARHGEF7,MCTP2,SELL,MGST2,IFT27,QSOX2,PDGFA,RGS3,IMPAD1,KCNK5,DIXDC1,CTTN,GFI1,BTBD3,SLC16A5,MCCC2,ITCH,MPP1,CASP9,SPA17,CCBL2,ATP8B3,YES1,PTGFRN,ADRBK2,NT5C2,PPP2R5A,ETS2,PAPD5,DHTKD1,ACADM,GEM,SERPINB1,CPPED1 |
| 1.531e-02 | -4.18 | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN | 184 | 38 | 17758 | 2588 |
GSDMD,GAA,HECA,TTC39B,FAM160B1,GGA1,ARL4C,EGR3,SLC20A1,TFAP4,AIM1L,OTUD1,ATP6V0B,ITGA3,BCL6,TNFRSF18,RFX5,NOTCH3,FAM84B,MYLIP,SMYD5,SPRY2,OPLAH,PLEKHA6,ADCK3,TEF,PANK1,ARFRP1,ASB13,BBS2,SOCS3,LEMD2,MAN2A2,AGPAT2,NR1D2,PDXK,CBX7,ARHGEF4 |
| 1.540e-02 | -4.17 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | 792 | 137 | 17775 | 2585 |
LTBP1,GAA,CRYM,SLC25A13,ATP8A1,DHX8,TEX2,KIF26A,DNER,TMC1,PLS3,CDKN2C,TP73,NKAIN3,ARHGAP42,NUP210,TGFBR3,CTNNB1,DNAH6,SHC3,DPYSL2,ANKFN1,IL31RA,ATRNL1,RGS5,NTN4,SLC39A10,MCTP1,USP18,RNF165,ROR1,LDB2,SESN1,MYLK,TRAF3IP1,SERPINI1,SPRY4,TANC2,PDPR,GAB1,HS6ST3,FRMD4A,UBASH3B,ZCCHC24,MTL5,CNTNAP2,SH3RF2,MYO5C,ATG4A,WDFY1,CA2,IGF1R,GATA2,FRAS1,BDH1,SORL1,FNIP1,CADPS2,CACNA1D,HLA-C,SYTL3,KDELR1,HPS3,VEZT,BCL2L13,NPHP3,PDIK1L,C3orf58,NFIB,EGFR,STX3,PDE11A,CACHD1,NAAA,PLEKHH2,PRKAG2,HTT,DGAT2,RAB31,FGD6,CABIN1,MAP3K5,SEMA3A,NCKAP5,SUZ12,RHBDL3,TP53,GMPR,NUF2,RNF182,SLC7A2,ZNF385B,CDK14,KCTD15,ST5,LRP11,LGMN,CPD,PFKFB2,SYNE2,ACO1,UTRN,TANC1,CBL,IDE,POPDC3,BFSP1,TLE1,EFNA5,MAMDC2,PBX3,FAM160A2,ANKS1B,CALD1,GALNS,MSH6,MYO5A,PDGFC,ARHGEF28,MOSPD2,NUB1,SYBU,CXorf57,DIAPH2,MAML2,LRRC1,SKA1,C4orf27,ABLIM2,DDAH1,MAMDC4,SWAP70,RCBTB2,SYT7,RIN3,PPM1H,GRAMD1C |
| 1.541e-02 | -4.17 | PXN (paxillin) | protein interactions | 5829 | 107 | 26 | 16036 | 2547 |
CASP3,ADAM17,SORBS1,REPS2,NF2,DSTN,IQGAP1,ARHGEF7,ITGA6,PTPRH,SDC4,HDAC6,CBL,ILK,BCAR1,RASA1,ZYX,FYN,IGF1R,PTEN,LIMK1,TUBG1,AHCY,CTTN,ITGAV,SYK |
| 1.541e-02 | -4.17 | lumenal side of endoplasmic reticulum membrane | cellular component | GO:0098553 | 28 | 9 | 17570 | 2579 |
CALR,HLA-B,TAPBP,HLA-F,HLA-E,PKD2,HLA-C,BCAP31,HLA-A |
| 1.541e-02 | -4.17 | integral component of lumenal side of endoplasmic reticulum membrane | cellular component | GO:0071556 | 28 | 9 | 17570 | 2579 |
CALR,HLA-B,TAPBP,HLA-E,HLA-F,PKD2,HLA-C,BCAP31,HLA-A |
| 1.547e-02 | -4.17 | cortical cytoskeleton | cellular component | GO:0030863 | 83 | 20 | 17570 | 2579 |
LASP1,NF2,MPP1,DMTN,DSTN,FLOT1,EZR,PLS1,ANLN,SPTB,CAPN2,PLEKHH2,SCNN1A,CDH1,LLGL2,CALD1,SPTBN5,CTTN,SHROOM2,FLOT2 |
| 1.553e-02 | -4.17 | GINM1 (glycoprotein integral membrane 1) | protein interactions | 116254 | 53 | 15 | 16036 | 2547 |
LTBP1,ITGB8,MGAT1,GALNT12,FAM234B,HLA-F,CLSTN1,TPST1,CANT1,LRP11,CHPT1,NDFIP1,QSOX2,DAG1,GLCE |
| 1.553e-02 | -4.16 | LIM | smart domains | SM00132 | 72 | 19 | 9131 | 1455 |
LMO7,FBLIM1,LASP1,CRIP2,LMCD1,FHL2,PRICKLE1,MICALL2,ABLIM2,ZYX,PDLIM3,LIMK1,PRICKLE4,LMO4,PRICKLE3,LHX6,LIMCH1,FHL1,CSRP2 |
| 1.554e-02 | -4.16 | CHEBOTAEV_GR_TARGETS_UP | MSigDB lists | CHEBOTAEV_GR_TARGETS_UP | 73 | 18 | 17758 | 2588 |
NR3C1,LAP3,DDIT4L,ABCG2,NDRG2,TRIB2,DOCK5,EDNRA,TFAP2E,IL17RB,ENPP1,ADD3,ATP1A1,MGAT4A,P4HA2,ITPR1,TSPAN13,SULF2 |
| 1.554e-02 | -4.16 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | MSigDB lists | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | 73 | 18 | 17758 | 2588 |
RASGRF1,ARHGEF3,RHOA,ARHGEF11,PIK3R1,GNB2,RHOB,ARHGEF16,ABR,RAC2,GNB5,PIK3CA,ARHGAP4,TIAM1,ARHGEF9,NGEF,FGD1,ARHGEF4 |
| 1.554e-02 | -4.16 | cellular amino acid catabolic process | biological process | GO:0009063 | 119 | 27 | 16441 | 2455 |
PRODH,SHMT1,ALDH6A1,GCAT,AASS,CRYM,HAL,ASL,MCCC1,CCBL2,OAT,AMDHD1,DDAH1,ALDH5A1,ACADSB,ABHD12,PCYOX1,ALDH7A1,GOT1,AHCY,HMGCL,ACAD8,ETHE1,GAD1,MCCC2,FAH,CTH |
| 1.554e-02 | -4.16 | CDH1 (cadherin 1, type 1) | protein interactions | 999 | 102 | 25 | 16036 | 2547 |
CASP3,NDRG1,IQGAP1,EZR,CBLL1,VEZT,YES1,RAD17,ERBB2IP,ILK,DDR1,LMNA,EGFR,PTPRF,FYN,CDH1,CTNNB1,PTEN,E2F1,ARVCF,CDH3,HDAC1,CTNND1,PPP1CA,ARPC2 |
| 1.555e-02 | -4.16 | Sphingolipid metabolism | REACTOME pathways | R-HSA-428157 | 76 | 19 | 8202 | 1235 |
HEXB,ASAH1,SPTLC2,ARSK,CPTP,SGPP1,SGPL1,KDSR,ALDH3B1,FA2H,ARSG,PLPP3,CTSA,GLB1,GLA,ARSB,ALDH3A2,GM2A,CERS2 |
| 1.556e-02 | -4.16 | histone-serine phosphorylation | biological process | GO:0035404 | 11 | 5 | 16441 | 2455 |
PRKAA2,AURKA,AURKB,CCNB1,PRKAA1 |
| 1.556e-02 | -4.16 | regulation of respiratory burst | biological process | GO:0060263 | 11 | 5 | 16441 | 2455 |
DUSP10,RAC2,INSR,CAMK1D,NOXA1 |
| 1.556e-02 | -4.16 | regulation of cell-cell adhesion mediated by cadherin | biological process | GO:2000047 | 11 | 5 | 16441 | 2455 |
EPCAM,WNT3A,FOXA1,FLOT1,RGCC |
| 1.556e-02 | -4.16 | negative regulation of type 2 immune response | biological process | GO:0002829 | 11 | 5 | 16441 | 2455 |
IL27RA,NDFIP1,STAT6,BCL6,SOCS5 |
| 1.556e-02 | -4.16 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly | biological process | GO:0045899 | 11 | 5 | 16441 | 2455 |
WNT10B,PSMC1,AHR,PSMC2,GTF2F2 |
| 1.556e-02 | -4.16 | dichotomous subdivision of an epithelial terminal unit | biological process | GO:0060600 | 11 | 5 | 16441 | 2455 |
TFAP2C,PLXND1,PLXNA1,AREG,SEMA3A |
| 1.557e-02 | -4.16 | Oxytocin signaling pathway | KEGG pathways | ko04921 | 157 | 35 | 6908 | 1076 |
PLA2G4A,PRKAA2,MYL9,PPP1R12A,CAMKK1,PRKAA1,CACNA2D2,CALM3,ITPR2,CAMK1D,CACNB4,PRKACA,CCND1,CALM2,PIK3CA,PIK3CD,PPP1CA,CACNA1D,MAPK7,PLCB2,CAMK2G,KCNJ12,RHOA,PIK3R1,CALM1,ELK1,ITPR3,FOS,EGFR,GNAS,PTGS2,PRKAG2,MYLK,ITPR1,PPP1CB |
| 1.557e-02 | -4.16 | Oxytocin signaling pathway | KEGG pathways | hsa04921 | 157 | 35 | 6908 | 1076 |
PLA2G4A,PRKAA2,MYL9,PPP1R12A,CAMKK1,PRKAA1,CACNA2D2,CALM3,ITPR2,CAMK1D,CACNB4,PRKACA,CCND1,CALM2,PIK3CA,PIK3CD,PPP1CA,CACNA1D,MAPK7,PLCB2,CAMK2G,KCNJ12,RHOA,PIK3R1,CALM1,ELK1,ITPR3,FOS,EGFR,GNAS,PTGS2,PRKAG2,MYLK,ITPR1,PPP1CB |
| 1.558e-02 | -4.16 | cytoplasmic vesicle part | cellular component | GO:0044433 | 561 | 101 | 17570 | 2579 |
SUN1,DOC2A,LAMP1,IL15RA,SLC2A8,ATP8A1,BCL2L1,SYTL4,SAYSD1,SNX9,PDGFB,PHLDA1,PICK1,APPBP2,SH3KBP1,PDGFA,CD46,ATP6V0B,AP1M2,N4BP3,SMO,DNM2,RAB20,LMAN1,PACSIN1,RAB27B,MYRIP,FLOT2,CPE,SMAGP,LAMP3,MYO5B,LAMP2,SEC23A,CLCN3,FZD4,SNTB2,SYP,RAB38,SLC17A5,MCFD2,ULK2,GABARAPL1,GPRC5B,DNM1L,AREG,RAB11FIP1,NRGN,COPG1,ARFGEF3,ANXA3,HSP90B1,TAOK2,PACSIN2,CD63,BACE1,HLA-F,HLA-E,RAB23,HLA-A,FZD6,ITGA2B,MARCH8,CALR,RAC2,TIMP1,SNX18,ZNRF2,OCRL,CD9,ZDHHC13,CADPS2,HLA-C,WNT3A,GAD1,CAMK2G,GPR161,TMED2,SNX7,KDELR1,SYPL1,RAB3B,VAMP3,ATP8B3,C3orf58,EGFR,HLA-B,LDLRAP1,SERPINA1,RAB11FIP2,SYT7,HTT,TMEM30A,ITPR1,RAB31,DYSF,ARRB1,GPER1,FZD5,TBC1D4,TMEM173 |
| 1.560e-02 | -4.16 | TGTGTGA,MIR-377 | MSigDB lists | TGTGTGA,MIR-377 | 190 | 39 | 17758 | 2588 |
KLK10,CPEB4,RET,STRN4,XIAP,OSGIN2,CACNA2D2,CUL1,C6orf106,RNF182,BCL2L1,PRR7,ETS1,HDAC9,ZFX,REEP1,FUT8,CDKN1B,SLC39A10,STK35,TMX1,TMED2,ZNF462,SOD1,FZD4,CRB3,RNF165,WHSC1,SLC11A2,FAM133B,PRX,RASA1,KLHL2,PITX2,CAMK2N2,MADD,UBE2D2,TRIOBP,NRG1 |
| 1.560e-02 | -4.16 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP | 190 | 39 | 17758 | 2588 |
GALK1,AGRN,ENO2,CD63,NDRG1,MORF4L2,NANS,SPSB1,LMNA,ZFP36,SIVA1,SLC44A1,TNFRSF18,SELK,RNASEH2A,NUP85,TSPAN33,ABCC1,PPIF,UFD1L,SHMT1,TNIP1,GCLC,NFE2L1,PTGER4,PRRC1,CD40,RNF19B,TP53INP2,GLCE,GABARAPL1,PRIM1,CD83,IDE,PLK2,SERPINB1,PSMC1,ACOT7,ZC3HC1 |
| 1.560e-02 | -4.16 | GSE360_DC_VS_MAC_T_GONDII_UP | MSigDB lists | GSE360_DC_VS_MAC_T_GONDII_UP | 190 | 39 | 17758 | 2588 |
COL9A3,TNK1,PCOLCE,TXN,PSME2,PDGFRL,HMGN3,BCL2L1,TIPRL,DUSP5,PPP2R3A,PARM1,NRP2,B4GALNT1,CTGF,CTSC,ARVCF,TACSTD2,OSTF1,GFI1,PSMA5,FAM69A,IGSF3,LAMP3,PDHX,CD83,RGS9,TIMP3,DHRS2,WFS1,MATN2,SPINT2,NMI,NR4A3,MAOA,APBA2,ARSB,TRAF5,ACOT7 |
| 1.560e-02 | -4.16 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDM_DN | 190 | 39 | 17758 | 2588 |
HLA-E,NDRG1,ATP8A1,ABCG2,PSMD7,KCTD12,HMGN3,GPSM2,MAGOHB,TAF1B,EFR3A,ZFP36,FUT8,KLF3,MDFIC,RFX5,TFG,SGCB,CPE,RASGRP1,TLE6,FARP2,ATG4D,AMOTL2,MPP1,BCL9,NUB1,SAV1,FNDC3A,CD83,NAT1,CSF1,SPINT2,TRIOBP,MPP2,HDAC1,IRF7,ST3GAL1,TOB1 |
| 1.560e-02 | -4.16 | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP | 190 | 39 | 17758 | 2588 |
HECA,GOLIM4,TNRC6C,SORBS1,CAMKK1,ARL4C,NOTCH2,ZNRF3,SEPP1,SLC20A1,HLA-A,NRP2,IER3,SLC25A45,FRY,FAM160A2,CDKN1B,SGK1,PIK3CD,C10orf54,MYLIP,RASGRP1,SULF2,SERTAD3,TCF7,YES1,TANC1,DOCK5,AMZ2,PLCG1,JAK1,ACYP1,NR1D2,STK38,STAT6,C1orf21,PGM2L1,ACADM,TTC39C |
| 1.561e-02 | -4.16 | GRESHOCK_CANCER_COPY_NUMBER_UP | MSigDB lists | GRESHOCK_CANCER_COPY_NUMBER_UP | 314 | 60 | 17758 | 2588 |
LASP1,NF2,TRIM24,SUZ12,RET,TP53,ERBB2,COX6C,PDGFB,FLT3,STIL,KTN1,EXT2,PSIP1,MECOM,CCND1,SS18,RB1,CDH1,CTNNB1,PTEN,CNTRL,SMO,MSH2,BCL6,PIK3CA,ERCC2,PIM1,TFG,NFKB2,ETV4,SYK,NCOA2,MSH6,DDB2,BCL9,WHSC1,CBL,FANCE,EGFR,LCP1,NIN,FAS,BCL10,USP6,GNAS,KDSR,TSC1,BTG1,HLF,CCDC6,FGFR2,HOXA9,NR4A3,HMGA1,RPL22,LIFR,ARNT,HOXC13,PRKAR1A |
| 1.561e-02 | -4.16 | lung-carcinoma-mixed_adenosquamous_carcinoma | COSMIC cancer mutations | lung-carcinoma-mixed_adenosquamous_carcinoma | 111 | 25 | 17775 | 2585 |
DCAF6,AKT1,RET,TP53,RHPN2,ERBB2,IDH1,FLT3,EGFR,GNAS,KIF5B,HLA-B,RB1,CTNNB1,CDH1,ANKS1B,PTEN,FGFR2,CCDC6,PIK3CA,PLEKHG1,SMO,TFG,JAK3,TLL2 |
| 1.561e-02 | -4.16 | GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 167 | 35 | 17758 | 2588 |
UNC93B1,KIF3C,XYLT1,MCCC1,TGOLN2,FAM198B,CAMK1D,MGST2,MAP1LC3B,IFT27,SYTL2,CYHR1,FAM13B,PCYOX1,SLC44A2,MARCH2,PDE4D,SLC35A1,CTDSP2,SH3BGRL,OXR1,RNF11,BNIP3L,TMTC2,PRKRA,DOCK5,LEPR,PEX5,TBC1D17,SERTAD2,PAFAH1B3,STK38,GLB1,RUSC1,FAM134B |
| 1.562e-02 | -4.16 | BURTON_ADIPOGENESIS_9 | MSigDB lists | BURTON_ADIPOGENESIS_9 | 89 | 21 | 17758 | 2588 |
GRN,PLA2G4A,AMOTL2,PCGF5,HEBP1,BCAR1,FOS,PHLDA1,MAGED2,PTGS2,SPP1,CYR61,CSF1,PLK2,MAOA,CTNND1,GEM,CITED2,F2R,ANXA11,EPHX1 |
| 1.562e-02 | -4.16 | WNT_SIGNALING | MSigDB lists | WNT_SIGNALING | 89 | 21 | 17758 | 2588 |
FZD4,BCL9,AES,TCF7,PYGO1,KREMEN1,FZD6,FZD7,CXXC4,CTNNBIP1,CCND1,PITX2,CTNNB1,CSNK1G1,NKD1,TLE1,DIXDC1,FZD5,WNT3A,CTBP1,DVL2 |
| 1.563e-02 | -4.16 | SH2 | smart domains | SM00252 | 112 | 27 | 9131 | 1455 |
INPPL1,INPP5D,STAT4,PIK3R1,TNS1,TEC,YES1,RASA1,SH2D4A,SOCS3,TXK,BCAR3,TNS4,PLCG1,TNS3,FYN,JAK1,SHC3,RINL,STAT6,SH2D3C,RIN3,PLCG2,STAT1,JAK3,SYK,SOCS5 |
| 1.563e-02 | -4.16 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS | 854 | 147 | 17758 | 2588 |
CCNI,CNOT8,UBE2Z,ECI1,CHST2,PSMD1,UBE2T,NPNT,IL6ST,TSPAN6,AKR1B1,CRY2,PIK3CD,MYBL1,CERS2,CASP9,TNFAIP8L1,PTGFRN,SLC25A5,COL12A1,SEC14L2,IRX3,CDCA4,LIMK1,PRKCDBP,ADIPOR1,CTNND1,RTN3,NR2C2,DLAT,PCSK5,RECQL,NFKBIE,LRRFIP2,DNAJB2,ITGA6,FXYD3,STRN4,RAB23,SORBS3,FBLN1,IL18R1,PDXDC1,HPCAL4,LMNA,B3GALNT1,AHCY,SELK,NCAM1,MAPK7,ALDH3A2,KDELR1,QSOX1,LPGAT1,STX3,NMT2,GNAS,ONECUT1,FNTA,SLC4A4,HTT,AURKA,MDH1,CBX5,SORBS1,NQO1,BROX,PTTG1,DGKA,DDR1,KCTD9,IER3,CDH1,FRYL,REEP1,CDH3,GYS1,TWIST1,DLG3,SNX10,CTDSP2,DVL2,MBP,FIGNL1,CDC20,GLO1,NUSAP1,BCL7B,RAD17,CBL,CD40,SNX12,SP4,NFIX,PEX5,ATP1A1,STK38,MMP17,STAT6,SLC27A1,PLXND1,PDXK,MAPK12,PRKAR1A,CDS2,TM2D2,GTF3A,IFT27,SIRPA,CAPN2,CTNNBIP1,MDM1,PHF7,TFAP2A,FAM63A,TRIM21,BUB1,IGFBP2,KLF9,MAP3K7,RAG1,SYK,MYO5A,MED22,AMOTL2,WNT10B,CRB3,IFITM3,MPP1,PIK3R1,FOS,NPDC1,CNTNAP1,BTG1,PROM1,SWAP70,TWSG1,NR1D2,ACVRL1,CCDC6,HNRNPH2,FGF18,CDCA7L,NMI,GRIN2D,HOXB13,ITGAV |
| 1.564e-02 | -4.16 | respiratory tube development | biological process | GO:0030323 | 180 | 38 | 16441 | 2455 |
KLF2,HECA,GRHL2,EPAS1,TMTC3,THRA,MAN1A2,SOX9,CTSZ,GPSM2,PDGFA,TNS3,ITGA3,CTNNB1,CTGF,GPC3,TMBIM6,PPP1CA,PDE4D,SPRY2,THRB,ADAMTS2,HES1,ASXL1,RC3H2,SAV1,NPHP3,DAG1,NFIB,CRISPLD2,HS6ST1,FGFR2,PTK7,FGF18,PLOD3,LTA4H,FOXA1,PCSK5 |
| 1.568e-02 | -4.16 | negative regulation of viral process | biological process | GO:0048525 | 87 | 21 | 16441 | 2455 |
MX1,TRIM8,PLSCR1,TNIP1,APOBEC3D,IFITM3,TRIM5,APOBEC3H,TRIM35,FBLN1,TFAP4,FAM111A,SP100,STAT1,TRIM21,HDAC1,RNASEL,IFIT1,OAS3,APOBEC3G,TRIM62 |
| 1.568e-02 | -4.16 | establishment of cell polarity | biological process | GO:0030010 | 87 | 21 | 16441 | 2455 |
CENPA,FRMD4A,ARHGEF11,NDC80,EZR,SCRIB,MPP5,GPSM2,SPDL1,FRMD4B,MAP1B,WEE1,IGF1R,LLGL2,RAB11FIP2,HTT,PTK7,PRKCI,ARF6,NDE1,SPRY2 |
| 1.568e-02 | -4.16 | CRKL (v-crk avian sarcoma virus CT10 oncogene homolog-like) | protein interactions | 1399 | 92 | 23 | 16036 | 2547 |
GRN,PLSCR1,INPP5D,PIK3R1,BIK,PPFIBP2,ERBB2,NOTCH2,CBL,BCAR1,EGFR,LMNA,MSL1,INSR,IGF1R,PTEN,HNRNPH2,DNM2,AOX1,ERBB3,GAB1,SYK,SEPHS1 |
| 1.576e-02 | -4.15 | vertebrae | COSMIC cancer mutations | vertebrae | 68 | 17 | 17775 | 2585 |
B3GNT7,IFITM3,TP53,FAM81A,IDH1,FLT3,PHF1,EGFR,GNAS,RB1,CTNNB1,PTEN,CTSC,OSBPL3,PIK3CA,PLCB2,RUSC1 |
| 1.578e-02 | -4.15 | MOOTHA_PGC | MSigDB lists | MOOTHA_PGC | 405 | 75 | 17758 | 2588 |
SLC2A4,AVPI1,FOXM1,TMEM41B,SOD2,GATA3,NDRG2,MPP5,ITPR2,SLC20A1,PHLDA1,TYMP,MKRN3,ABCA2,GYS1,TINAGL1,MANF,CDKN2D,S100A13,GPX4,CKS2,FZD4,PLEKHO1,SAT1,BNIP3L,MRPS18A,ATP1B1,ZFAND5,SLC25A5,TCN2,EDNRA,DPYSL3,NFIX,GABARAPL1,CARHSP1,ATP1A1,SLC25A4,ACYP1,NGFRAP1,P4HA2,CAB39,PDXK,PCOLCE,LRRFIP2,AES,GDF15,DNAJB9,COX7A2,SAC3D1,SPP1,CA2,OXCT1,ARVCF,NCAM1,PSMA5,TRAK2,DUSP1,PGM1,SHMT1,PRSS23,LPGAT1,COL7A1,EIF2AK1,FXR2,FOS,SPTLC2,MAPKAPK2,PRDX3,TIMM8A,DBI,RAB31,CDK18,ACADM,ACOT7,EGLN1 |
| 1.578e-02 | -4.15 | L1CAM interactions | REACTOME pathways | R-HSA-373760 | 97 | 23 | 8202 | 1235 |
SCN5A,RPS6KA1,EZR,ALCAM,SPTB,RANBP9,ITGA2B,NRP2,EGFR,CNTNAP1,ANK1,RPS6KA2,DPYSL2,DLG1,DNM2,SPTBN5,ITGAV,SCN2A,NCAM1,DLG3,L1CAM,RPS6KA3,SCN3A |
| 1.580e-02 | -4.15 | cyclic nucleotide binding | molecular function | GO:0030551 | 37 | 11 | 16491 | 2452 |
BVES,RAPGEF2,PRKG1,PDE5A,PRKAR2B,PDE4D,CNGA1,TMEM173,PDE11A,PRKAR1A,HCN3 |
| 1.580e-02 | -4.15 | liver-other-hepatoblastoma | COSMIC cancer mutations | liver-other-hepatoblastoma | 33 | 10 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,AKT1,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 1.580e-02 | -4.15 | urinary_tract-bladder-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-squamous_cell_carcinoma | 33 | 10 | 17775 | 2585 |
CTNNB1,CDH1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 1.580e-02 | -4.15 | hepatoblastoma | COSMIC cancer mutations | hepatoblastoma | 33 | 10 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,AKT1,PIK3R1,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 1.584e-02 | -4.15 | regulation of production of molecular mediator of immune response | biological process | GO:0002700 | 103 | 24 | 16441 | 2455 |
KLK5,HLA-E,TRAF2,VAMP3,WHSC1,IL27RA,PKN1,CD40,HLA-A,BCL10,GPRC5B,STAT6,BCL6,NOD2,NR4A3,TMBIM6,KLK7,C10orf54,FZD5,MAP3K7,NDFIP1,F2RL1,JAK3,MSH6 |
| 1.585e-02 | -4.14 | CENPH (centromere protein H) | protein interactions | 64946 | 22 | 8 | 16036 | 2547 |
CENPA,CENPI,RASSF7,NDC80,NUF2,KIF2C,CENPN,VCP |
| 1.585e-02 | -4.14 | PPP1R16A (protein phosphatase 1, regulatory subunit 16A) | protein interactions | 84988 | 22 | 8 | 16036 | 2547 |
HLA-E,PPP1R16A,PAPSS1,PPP1CB,AES,PPP1CA,FAM101B,RGMA |
| 1.585e-02 | -4.14 | RHOG (ras homolog family member G) | protein interactions | 391 | 22 | 8 | 16036 | 2547 |
ELMO2,MCF2L,MAP3K11,TGFBR1,PLD1,FBXO6,KTN1,ELMOD2 |
| 1.586e-02 | -4.14 | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDM_UP | 196 | 40 | 17758 | 2588 |
IER5L,MRPL44,DAP,HABP4,TP53,GMPR,NUF2,MGST2,HDAC6,SLC25A35,XPR1,SLC46A1,HMGCL,IQGAP3,CNOT6L,ITM2C,GPX4,CENPA,MBP,TMEM43,LPGAT1,ACO1,GLO1,SESN1,FRMD4B,ANKRD10,LDLRAP1,RBM47,NR1D2,LIMK1,PLA2G15,CDCA7L,NR4A3,ARRB1,FAM117A,MDH1,CENPE,CCNB2,MYL12B,CPPED1 |
| 1.586e-02 | -4.14 | GSE339_CD8POS_VS_CD4CD8DN_DC_DN | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_DN | 196 | 40 | 17758 | 2588 |
RECQL,ARHGEF3,NLRX1,CYP2J2,ARL4C,KIF2C,B4GALNT1,MDM1,ENTPD4,NPNT,RGS3,FAM13B,ABCA2,ECI2,RPGR,S100A6,GPX4,SMARCA2,TMEM68,FBXO8,EMP3,GGH,TCF7,SESN1,POR,ULK2,BCL10,MDK,IL1R1,PTGS2,COL13A1,TIMM8A,H1F0,MMP17,ABCB1,NR4A2,PLXND1,PDXK,B4GALT3,RGS14 |
| 1.588e-02 | -4.14 | BROWN_MYELOID_CELL_DEVELOPMENT_DN | MSigDB lists | BROWN_MYELOID_CELL_DEVELOPMENT_DN | 122 | 27 | 17758 | 2588 |
BIN1,SOD1,PAPSS2,IFITM3,PTPN9,GNAL,PDIA5,TMTC2,TXK,ANKRD10,CALR,IDE,GATA2,TIMM8A,KCNK5,OSBPL3,FUT8,SPINT2,PGRMC1,MSH2,RGS5,AHCY,RAB27B,F2R,NRGN,MGAT5,SYTL3 |
| 1.589e-02 | -4.14 | regulation of protein exit from endoplasmic reticulum | biological process | GO:0070861 | 19 | 7 | 16441 | 2455 |
SORL1,YOD1,GCC2,ERLEC1,BCAP31,TMEM30A,UBE2J1 |
| 1.589e-02 | -4.14 | smooth muscle tissue development | biological process | GO:0048745 | 19 | 7 | 16441 | 2455 |
PKD2,OSR1,ZFAND5,TIPARP,SOX9,MYLK,DLG1 |
| 1.589e-02 | -4.14 | microtubule nucleation | biological process | GO:0007020 | 19 | 7 | 16441 | 2455 |
TUBG1,SLAIN2,NDE1,CENPJ,RANBP9,TUBGCP6,NIN |
| 1.589e-02 | -4.14 | regulation of calcineurin-NFAT signaling cascade | biological process | GO:0070884 | 19 | 7 | 16441 | 2455 |
RCAN2,NRG1,ERBB3,RCAN3,NFAT5,LMCD1,CHP1 |
| 1.591e-02 | -4.14 | Nuclear Receptor transcription pathway | REACTOME pathways | R-HSA-383280 | 51 | 14 | 8202 | 1235 |
THRB,NR3C1,NR1D2,NRBF2,NR4A1,THRA,PPARA,NR4A3,NR4A2,NR3C2,RARG,NRBP1,NR2C1,NR2C2 |
| 1.598e-02 | -4.14 | GSE12366_GC_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE12366_GC_BCELL_VS_PLASMA_CELL_DN | 173 | 36 | 17758 | 2588 |
CCNC,TMEM184B,HSPG2,HOXB7,CRYM,DNAJC3,BTN3A1,PSME1,MORF4L2,CHPF,DAPK2,TM9SF2,MGAT1,OSBPL3,PAPSS1,SGK3,ITM2C,FBXL16,CD55,BCL9,PARP4,BTN3A2,KIF1C,RNF113A,PRRC1,PRX,SOCS3,PRDX4,SCARB2,ABHD12,COL13A1,FAM114A1,NETO2,STAT1,ARFGAP3,IRF7 |
| 1.598e-02 | -4.14 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP | 173 | 36 | 17758 | 2588 |
ZNF395,CKAP2,RASGRP3,ETS1,CDK14,ADD3,SP100,CD22,PLCG2,FUT8,PIKFYVE,RASGRP1,SMAGP,SYPL1,KIAA0040,EZR,EAF2,CYFIP2,CDK5R1,RASGRP2,STK17A,CD83,ARHGAP24,BTG1,SWAP70,BANK1,WDR11,FAM3C,SIPA1L1,CSGALNACT1,PIK3C2B,TTC9,CD81,TRAF5,PKIA,EHD1 |
| 1.598e-02 | -4.14 | FYB (FYN binding protein) | protein interactions | 2533 | 18 | 7 | 16036 | 2547 |
PRKCQ,FYN,VASP,MAP3K7,CBL,BCAR1,BCL10 |
| 1.598e-02 | -4.14 | SEC63 (SEC63 homolog, protein translocation regulator) | protein interactions | 11231 | 18 | 7 | 16036 | 2547 |
ACADM,SEC61B,DDOST,ABCC1,TP53,IRF1,SPA17 |
| 1.598e-02 | -4.14 | PRPSAP2 (phosphoribosyl pyrophosphate synthetase-associated protein 2) | protein interactions | 5636 | 18 | 7 | 16036 | 2547 |
WHSC1,PSMD10,MTRF1L,CBL,IQGAP1,PRPS2,DCUN1D1 |
| 1.600e-02 | -4.14 | p38 MAPK Signaling Pathway | WikiPathways | WP400 | 34 | 11 | 4455 | 729 |
MAPKAPK2,PLA2G4A,RASGRF1,TRAF2,STAT1,MAP3K9,TGFBR1,ELK1,MAP3K5,MAP3K7,HSPB1 |
| 1.603e-02 | -4.13 | PID_EPO_PATHWAY | MSigDB lists | PID_EPO_PATHWAY | 33 | 10 | 17758 | 2588 |
IRS2,PLCG1,INPP5D,PLCG2,PIK3R1,STAT1,BCL2L1,CBL,GAB1,SOCS3 |
| 1.603e-02 | -4.13 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | MSigDB lists | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | 33 | 10 | 17758 | 2588 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP2C2,ATP8B1,ATP8B3,ATP1B1,ATP1B3,ATP10D |
| 1.603e-02 | -4.13 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | MSigDB lists | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | 33 | 10 | 17758 | 2588 |
CALM2,RASGRF1,RPS6KA2,CAMKK1,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D,RPS6KA3 |
| 1.603e-02 | -4.13 | CHROMOSOME_SEGREGATION | MSigDB lists | CHROMOSOME_SEGREGATION | 33 | 10 | 17758 | 2588 |
TOP2A,REC8,ZWINT,PAPD7,CDCA5,NDC80,NUSAP1,CENPE,ESPL1,SMC4 |
| 1.603e-02 | -4.13 | ROZANOV_MMP14_TARGETS_DN | MSigDB lists | ROZANOV_MMP14_TARGETS_DN | 33 | 10 | 17758 | 2588 |
SIGIRR,NOV,PIK3R1,SDC4,TRIOBP,PGM2L1,SNTB1,UBE2C,GAD1,EHD1 |
| 1.603e-02 | -4.13 | DUTTA_APOPTOSIS_VIA_NFKB | MSigDB lists | DUTTA_APOPTOSIS_VIA_NFKB | 33 | 10 | 17758 | 2588 |
TRAF2,XIAP,SOD2,TP53,BAX,FTH1,CD274,BCL2L1,FAS,IER3 |
| 1.607e-02 | -4.13 | ACACTCC,MIR-122A | MSigDB lists | ACACTCC,MIR-122A | 68 | 17 | 17758 | 2588 |
MARK1,SLC39A8,IQGAP1,CALM1,CALM3,NFAT5,CALM2,CCDC6,H1F0,SLC9A6,SLC4A3,ZDHHC7,GYS1,CCDC97,OCLN,RAD21,TBC1D10B |
| 1.607e-02 | -4.13 | Interleukin-6 signaling | REACTOME pathways | R-HSA-1059683 | 11 | 5 | 8202 | 1235 |
JAK1,CBL,IL6ST,STAT1,SOCS3 |
| 1.607e-02 | -4.13 | RHO GTPases activate KTN1 | REACTOME pathways | R-HSA-5625970 | 11 | 5 | 8202 | 1235 |
KIF5B,RHOA,KTN1,KLC2,KLC3 |
| 1.608e-02 | -4.13 | mitogen-activated protein kinase kinase binding | molecular function | GO:0031434 | 15 | 6 | 16491 | 2452 |
ARRB1,DAB2IP,TAOK2,TRIB2,DLG1,MAP3K11 |
| 1.608e-02 | -4.13 | inositol phosphate phosphatase activity | molecular function | GO:0052745 | 15 | 6 | 16491 | 2452 |
INPP5E,MINPP1,PTEN,IMPAD1,OCRL,INPP5D |
| 1.609e-02 | -4.13 | human chr5q23.3 | chromosome location | human chr5q23.3 | 10 | 4 | 26250 | 2805 |
CHSY3,FNIP1,SLC27A6,SLC12A2 |
| 1.610e-02 | -4.13 | chr9q34 | MSigDB lists | chr9q34 | 202 | 41 | 17758 | 2588 |
IER5L,RNF224,GPR107,FAM129B,CERCAM,TRAF2,SWI5,FAM78A,QSOX2,C9orf69,INPP5E,NOXA1,ZDHHC12,LHX6,DAPK1,ABCA2,FAM102A,MED22,C9orf9,OLFML2A,RC3H2,GRIN1,UBAC1,FAM73B,AIF1L,NPDC1,TSC1,MAMDC4,AGPAT2,ZMYND19,DOLPP1,FIBCD1,SLC2A6,PPP2R4,SH3GLB2,ARRDC1,EGFL7,SSNA1,POMT1,PTGES,FBXW5 |
| 1.611e-02 | -4.13 | Frizzled | pfam domains | PF01534 | 11 | 5 | 16629 | 2504 |
FZD5,FZD4,FZD7,FZD6,SMO |
| 1.611e-02 | -4.13 | SAM_PNT | pfam domains | PF02198 | 11 | 5 | 16629 | 2504 |
ETS2,ETV7,ETS1,ELF5,ELF3 |
| 1.611e-02 | -4.13 | Filamin | pfam domains | PF00630 | 11 | 5 | 16629 | 2504 |
TRIM3,TRIM2,AREL1,KDELC2,TRIM45 |
| 1.611e-02 | -4.13 | 2OG-FeII_Oxy_3 | pfam domains | PF13640 | 11 | 5 | 16629 | 2504 |
EGLN3,P4HA2,P3H2,P4HA3,EGLN1 |
| 1.612e-02 | -4.13 | regulation of lymphocyte proliferation | biological process | GO:0050670 | 186 | 39 | 16441 | 2455 |
CASP3,LGALS3,DHPS,IL15,INPP5D,HLA-E,ERBB2,IL18,CD274,PKN1,TNFSF9,EFNB1,HLA-A,CD46,RAC2,CTNNB1,IL6ST,BCL6,DLG1,IGFBP2,C10orf54,WNT3A,SLC39A10,SYK,HES1,CD55,RIPK2,ITCH,PDE5A,PRKCQ,CD40,IRS2,ICOSLG,CD81,JAK3,NDFIP1,AHR,IRF1,PRKAR1A |
| 1.613e-02 | -4.13 | Constitutive Signaling by Aberrant PI3K in Cancer | REACTOME pathways | R-HSA-2219530 | 61 | 16 | 8202 | 1235 |
PIK3R1,NRG2,ERBB2,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,FGFR2,FGF18,PIK3CA,NRG1,PIK3CD,ERBB3,GAB1 |
| 1.616e-02 | -4.13 | head development | biological process | GO:0060322 | 693 | 124 | 16441 | 2455 |
EMX1,CASP3,NF2,HSPG2,GRHL2,AK7,THRA,CAST,SUDS3,TP53,NDRG2,OSR2,SEPT4,STIL,PHLDA1,SDF4,TP73,TTC21B,CALM2,APLP2,CDH1,CTNNB1,TACC2,DPYSL2,KIF14,ALDH1A3,LHX6,SRR,SMO,DAB2IP,DIXDC1,ARNT2,NOTCH3,ZBTB18,TIPARP,BTBD3,SPEF2,MBP,CELSR2,FZD4,TFAP2C,ZFAND5,ARF4,ABR,ARHGAP35,NFIX,EDNRA,IRS2,MDK,FYN,PAFAH1B3,TBX1,AXL,TRABD2A,NRG1,NRGN,ANXA3,SCN5A,CDH22,SERPINE2,ADGRG1,CALM3,NES,CNTNAP2,SEPP1,ETS1,PGAP1,HOXB2,FZD6,GBX2,SGPL1,MECOM,FOXP2,BMP2,OXCT1,IGF1R,GATA2,PTEN,KNDC1,FLRT3,CST3,CD9,PRKG1,BAX,WNT3A,POU6F1,HES1,RHOA,TACC1,ASPM,RAPGEF2,CALM1,SHARPIN,GRIN1,AK4,TCF7,SCRIB,BBS2,NFIB,CRISPLD2,EGFR,CDK5R1,FAS,PITX2,CDK5RAP1,TSC1,CTNS,FAT4,HTT,FGFR2,TWSG1,PHLPP2,DBI,RYK,NR4A3,E2F1,PCDH19,NR4A2,NDE1,WDR62,SHROOM2,SEMA3A,RARG,DRD1 |
| 1.617e-02 | -4.12 | maintenance of protein location in cell | biological process | GO:0032507 | 82 | 20 | 16441 | 2455 |
SUN1,SUN2,PINK1,NFKBIE,AKT1,SYNE3,THRA,SYNE2,EZR,KDELR3,PSMD10,PDIA3,DAG1,NFKBIA,SORL1,PKD2,SUN3,TLN2,KDELR1,MDFI |
| 1.617e-02 | -4.12 | receptor metabolic process | biological process | GO:0043112 | 82 | 20 | 16441 | 2455 |
AGRN,EZR,CALCRL,PLD2,ZNRF3,FAM109A,ADRBK2,LDLRAP1,FNTA,ADRBK1,FUT8,DNM2,CD9,RAB31,ARRB1,NRG1,LGMN,CD81,SYK,CAPN1 |
| 1.620e-02 | -4.12 | BROWN_MYELOID_CELL_DEVELOPMENT_UP | MSigDB lists | BROWN_MYELOID_CELL_DEVELOPMENT_UP | 156 | 33 | 17758 | 2588 |
GRN,LASP1,ARHGEF3,NQO1,S100A11,HEBP1,IQGAP1,HEXB,MXD1,SIRPA,GNS,DOPEY2,ZYX,SP100,SLC30A6,CAPG,C10orf54,S100A6,SOAT1,CPD,QSOX1,DSTN,PLAUR,SAT1,PYGL,ALCAM,SCARB2,SLC6A6,DGAT2,SLC31A2,CD33,XDH,ESYT2 |
| 1.623e-02 | -4.12 | ACTININ_2 | prosite domains | PS00020 | 23 | 8 | 11866 | 1802 |
SYNE2,UTRN,CLMN,PLS1,SPTBN5,SPTB,LCP1,PLS3 |
| 1.623e-02 | -4.12 | ACTININ_1 | prosite domains | PS00019 | 23 | 8 | 11866 | 1802 |
SYNE2,UTRN,CLMN,PLS1,SPTBN5,SPTB,LCP1,PLS3 |
| 1.624e-02 | -4.12 | CHROMODOMAIN | prints domains | PR00504 | 8 | 4 | 4759 | 661 |
CBX5,CBX7,CBX4,CBX6 |
| 1.626e-02 | -4.12 | positive regulation of JNK cascade | biological process | GO:0046330 | 114 | 26 | 16441 | 2455 |
TAOK2,RIPK2,FZD4,TRAF2,EPHA4,PKN1,FGF19,MAP3K6,FZD7,CTGF,ANKRD6,KIAA1804,MAP3K9,MAP3K11,NOD2,DAB2IP,MDFIC,FZD5,MAP3K5,MAP3K7,F2RL1,SYK,GAB1,RASGRP1,DVL2,MDFI |
| 1.626e-02 | -4.12 | reactive oxygen species metabolic process | biological process | GO:0072593 | 114 | 26 | 16441 | 2455 |
P2RX4,SOD1,NQO1,RFK,AKT1,CALM1,SOD2,CALM3,P2RX7,SLC7A2,PDGFB,SPR,POR,PRDX4,ZDHHC21,CALM2,DDAH1,DUOX1,CYP1A1,NOXA1,CTGF,CYR61,PRDX3,DNM2,AOX1,CYP1B1 |
| 1.628e-02 | -4.12 | V$AP4_Q5 | MSigDB lists | V$AP4_Q5 | 255 | 50 | 17758 | 2588 |
SLC25A24,APBA1,DHRS3,TNFRSF19,PDGFB,PSIP1,SYTL2,TFAP4,IRF2BPL,PAK6,ADRBK1,PHF7,LRRN2,STIM1,CASC4,REEP1,ANKRD12,ATRNL1,VAT1,ERBB3,ZRANB1,CITED2,SULT2B1,TRAM1,TRIM62,DOCK4,MAP3K3,SMARCA2,MBP,PLEKHA6,WNT10B,RGAG1,VAMP3,EMP3,PRICKLE1,TCF7,PRKCQ,B3GALNT2,TP53INP2,ABR,PGF,ARHGAP24,BTG1,INSR,PTK7,NR4A3,E2F1,RHOBTB2,GRIN2D,ZMIZ1 |
| 1.628e-02 | -4.12 | V$MYCMAX_B | MSigDB lists | V$MYCMAX_B | 255 | 50 | 17758 | 2588 |
RBM24,EPS8,CALM3,EGR3,CRABP2,PDGFB,HPCAL4,H1FX,IRF2BPL,CCND1,CALM2,TFAP4,WEE1,DAZAP1,PHF7,CDK16,ZNRF2,XYLT2,BHLHE41,TOX2,RANBP1,TNPO2,AK3,GFI1,EBAG9,SUN2,TGIF1,TRIM8,TMEM43,CALM1,TFAP2C,FXR2,KDM3A,SLC25A5,SOCS3,HSF4,PRKAG2,SYT7,RND3,PTK7,ZNF367,HOXA9,C1orf21,PITPNA,HS3ST3B1,HMGA1,ARF6,STARD13,RNF146,RPS6KA3 |
| 1.628e-02 | -4.12 | protein localization to vacuole | biological process | GO:0072665 | 37 | 11 | 16441 | 2455 |
NAGPA,ZFYVE16,GCC2,SCARB2,RNF128,GNPTAB,SH3BP4,SORL1,SNX16,TRAPPC8,CD81 |
| 1.632e-02 | -4.12 | GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP | 179 | 37 | 17758 | 2588 |
GCLM,CDK17,LGALS3,DAP,DGKQ,EPHA4,IL13RA1,BAIAP3,EXT2,MOCS1,WEE1,SPP1,CABP1,POF1B,NOTCH3,LGMN,FAIM,TRIM62,SMAGP,XKR8,HMGN5,HN1L,CRIP2,PRKAR2B,FANCE,FAS,RGS9,FAM64A,STK38,TCEAL4,TLE1,STK39,GRAMD1C,TBC1D4,MAFF,OCLN,KLF7 |
| 1.633e-02 | -4.11 | Toll Like Receptor TLR1:TLR2 Cascade | REACTOME pathways | R-HSA-168179 | 92 | 22 | 8202 | 1235 |
SIGIRR,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 1.633e-02 | -4.11 | Toll Like Receptor TLR6:TLR2 Cascade | REACTOME pathways | R-HSA-168188 | 92 | 22 | 8202 | 1235 |
SIGIRR,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 1.633e-02 | -4.11 | MyD88:Mal cascade initiated on plasma membrane | REACTOME pathways | R-HSA-166058 | 92 | 22 | 8202 | 1235 |
SIGIRR,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 1.633e-02 | -4.11 | Toll Like Receptor 2 (TLR2) Cascade | REACTOME pathways | R-HSA-181438 | 92 | 22 | 8202 | 1235 |
SIGIRR,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,NOD2,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 1.636e-02 | -4.11 | ENDOPLASMIC_RETICULUM_MEMBRANE | MSigDB lists | ENDOPLASMIC_RETICULUM_MEMBRANE | 84 | 20 | 17758 | 2588 |
PIGC,HSP90B1,AMFR,ERP44,KTN1,EXT2,TAPBP,CASP7,DDOST,STIM1,NECAB3,SLC9A6,LMAN2L,DOLPP1,BAX,RPN2,STT3B,POMT1,LMAN1,TMX1 |
| 1.637e-02 | -4.11 | MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED | 504 | 91 | 17758 | 2588 |
ILDR1,CCDC109B,GRHL2,NLRX1,PPM1J,ST14,HEBP1,FLYWCH2,DDIT4L,ABCG4,IRX4,NDRG2,LGI3,IL27RA,F11R,PHF1,EPS8L2,TFAP2E,NOV,AP1M2,CTGF,ARTN,PAQR5,PAPL,CLDN4,TACSTD2,TMEM37,SCARA3,LOXL1,FLOT2,SP5,GCA,SSH3,KREMEN2,SLC39A8,HSPA12A,HTATIP2,CMTM7,SLC44A3,HSF4,TRIM47,PLEKHG6,ZNF641,BFSP1,C19orf66,SHROOM3,FAM110C,DHTKD1,PRKCDBP,MAPK13,RBM43,F2RL1,PRR15,ANXA11,GSDMD,PLSCR4,LGALS3,IGFBP6,PARP14,CTSZ,ISYNA1,ANO1,MYO5C,IL17RB,SH3D21,CXCL16,SGK3,C10orf54,MOXD1,FAR2,FAH,GCNT1,DLGAP1,RAB3B,WNT10B,SYBU,GYLTL1B,PCTP,CRISPLD2,CD83,PRKAG2,TMEM54,RIN3,NR4A3,ABCB1,OSMR,CDK18,MAL2,RARG,PROM2,ARHGEF4 |
| 1.641e-02 | -4.11 | SH2 | prosite domains | PS50001 | 107 | 25 | 11866 | 1802 |
INPPL1,INPP5D,STAT4,PIK3R1,TNS1,TEC,YES1,RASA1,SH2D4A,SOCS3,TXK,BCAR3,TNS4,PLCG1,TNS3,FYN,JAK1,SHC3,STAT6,SH2D3C,RIN3,PLCG2,STAT1,SYK,SOCS5 |
| 1.641e-02 | -4.11 | Sertoli cell development | biological process | GO:0060009 | 15 | 6 | 16441 | 2455 |
SOX8,FNDC3A,SDC1,CST3,ICAM1,SOX9 |
| 1.641e-02 | -4.11 | regulation of fatty acid beta-oxidation | biological process | GO:0031998 | 15 | 6 | 16441 | 2455 |
IRS2,TWIST1,AKT1,TYSND1,PLIN5,PPARA |
| 1.641e-02 | -4.11 | metanephric nephron tubule development | biological process | GO:0072234 | 15 | 6 | 16441 | 2455 |
PKD2,HES1,OSR1,SOX8,LGR4,SOX9 |
| 1.641e-02 | -4.11 | determination of adult lifespan | biological process | GO:0008340 | 15 | 6 | 16441 | 2455 |
IDE,HTT,INPP5D,MSH6,TP53,MSH2 |
| 1.641e-02 | -4.11 | left/right axis specification | biological process | GO:0070986 | 15 | 6 | 16441 | 2455 |
EPB41L5,PITX2,SETDB2,CITED2,MNS1,SMO |
| 1.641e-02 | -4.11 | positive regulation of endothelial cell apoptotic process | biological process | GO:2000353 | 15 | 6 | 16441 | 2455 |
COL18A1,GPER1,CD40,ANO6,PRKCI,RGCC |
| 1.645e-02 | -4.11 | PLCG1 (phospholipase C, gamma 1) | protein interactions | 5335 | 149 | 34 | 16036 | 2547 |
GAS2L1,TNK1,IBTK,INPP5D,RET,ERBB2,PLD2,TEC,MVB12B,DDR1,TIPRL,PDGFA,CD22,CTPS1,ERBB3,NCAM1,SYK,RHOA,AKT1,GRIN1,CBL,RASA1,EGFR,IRS2,PTPRJ,INSR,FYN,JAK1,FGFR2,AXL,PITPNA,TRPC3,LIFR,GAB1 |
| 1.646e-02 | -4.11 | ADD1 (adducin 1 (alpha)) | protein interactions | 118 | 35 | 11 | 16036 | 2547 |
CASP3,SMARCA2,ATP1A1,CALM1,HDAC1,FAM78A,PRKACA,MAP1LC3B,ANKRD29,SPTB,VCP |
| 1.649e-02 | -4.11 | GRADE_COLON_AND_RECTAL_CANCER_UP | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_UP | 273 | 53 | 17758 | 2588 |
LAMP1,HJURP,CTSB,DCAF7,SOX9,SOD2,KIF23,DHX8,GTF3A,GDF15,GPSM2,CCNB1,PLA2G16,CCDC92,RCN1,SPP1,PCNA,IRAK1,TIMP1,GTF2F2,FXYD5,H2AFY,AHCY,KNTC1,SLC12A2,ETV4,SEPHS1,CKS2,PLK1,PMPCB,ZNF84,GCLC,SPATA13,TCF7,GLO1,NUSAP1,PDK3,BORA,CDK1,RHEB,PRDX4,MAGED2,CARHSP1,PAFAH1B3,ETS2,KBTBD2,NMI,DGAT2,SERPINB5,AURKA,PDXK,TRAF5,MELK |
| 1.654e-02 | -4.10 | PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | PROTEIN_TYROSINE_KINASE_ACTIVITY | 63 | 16 | 17758 | 2588 |
ERBB2,PDGFRL,ROR1,MERTK,DDR1,FLT3,EGFR,NRP2,TXK,INSR,IGF1R,AXL,PTK7,RYK,NR4A3,ERBB3 |
| 1.654e-02 | -4.10 | BYSTROEM_CORRELATED_WITH_IL5_DN | MSigDB lists | BYSTROEM_CORRELATED_WITH_IL5_DN | 63 | 16 | 17758 | 2588 |
NR3C1,FOXM1,PIK3R1,MXD1,MAPKAPK2,PTPRJ,CASP7,IL6ST,SORL1,PLD1,PIM1,PIK3CD,ERCC2,TRAM1,SYK,ARNT |
| 1.654e-02 | -4.10 | Ras activation uopn Ca2+ infux through NMDA receptor | REACTOME pathways | R-HSA-442982 | 19 | 7 | 8202 | 1235 |
CALM3,CALM2,GRIN2D,RASGRF1,CALM1,CAMK2G,GRIN1 |
| 1.654e-02 | -4.10 | aminopeptidase activity | molecular function | GO:0004177 | 42 | 12 | 16491 | 2452 |
DNPEP,LAP3,PRCP,CTSV,DPP9,ERAP1,F12,DPP8,LTA4H,RNPEP,ERAP2,METAP2 |
| 1.656e-02 | -4.10 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_I | 38 | 11 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,RET,PIK3CA,TP53,SMO,IDH1,GNA11,EGFR |
| 1.657e-02 | -4.10 | NRL_DN.V1_DN | MSigDB lists | NRL_DN.V1_DN | 128 | 28 | 17758 | 2588 |
QSOX1,INPPL1,ELK3,ALDH2,ERMAP,NR4A1,SLC25A13,RASA2,RGS20,PDIA3,ARHGDIB,PRKCQ,DPP8,SOCS3,PLEKHH2,CASP7,PIK3AP1,BAX,DYSF,TNPO2,DIXDC1,ECE1,MOXD1,TTLL1,TC2N,TSPAN33,FAM134C,CTH |
| 1.658e-02 | -4.10 | DANG_BOUND_BY_MYC | MSigDB lists | DANG_BOUND_BY_MYC | 1066 | 180 | 17758 | 2588 |
CCNC,LAMP1,KLK10,TXN,TSC22D3,XIAP,CCNB1,HDAC6,PDGFB,BARD1,SLC9A3R2,TSEN34,TYMP,PCNA,RPS6KA2,ARL1,FUT1,TUBG1,IRF2,ASH2L,MANF,SOD1,ING1,UXT,CASP9,CR2,ARFRP1,PRKRA,CLCN2,VCP,RHEB,ARF4,DPYSL3,MAN2A2,GDE1,SH2D3C,MADD,PPP2R4,EIF4EBP2,GLA,MAFF,DDX58,RECQL,SERPINE2,PPP1R12A,SCOC,PEX6,HLA-F,ITGA6,PSMD7,ASAH1,LMNA,GNS,CALR,RAC2,VASP,FRY,MSH2,SRP54,USP1,RFX5,ACAD8,MAPK7,SLC12A2,PSMA5,MCCC2,DNAI1,EPHX1,TRAK2,NAGPA,PMPCB,MFI2,KIF20A,TESK1,MYBL2,KIF20B,SRSF5,PDK3,ILK,ELK1,SPTLC2,NUBP1,FECH,MMP15,INSR,TIMM8A,DCK,PRPS2,SFMBT1,MDH1,MAP3K5,CBX5,PLA2G4A,LZTFL1,FOXM1,NDRG1,TP53,ERBB2,TESK2,EGR3,FAM198B,EPM2A,CDKN1B,FLOT2,NAGA,CKS2,SIRT1,CLCN3,SEC61B,RIPK2,AGPS,SLC39A8,CDC25C,SP4,ZMPSTE24,STX10,RBL1,PSMD3,CORO1C,STAT6,PPP1CB,FAM149A,RPL22,LTA4H,CTDSP1,NUDT6,CMAS,PINK1,HSP90B1,ENO2,JRKL,CD63,ARHGEF7,PSMD10,GSTP1,LBR,NFAT5,ICAM1,M6PR,SGPL1,CXCL16,PDCD10,CDK16,CTSC,BAX,TRIM3,H2AFY,BUB1,TAGLN2,IQGAP3,SYK,FAH,HMMR,SYPL1,HES1,SHMT1,ALDH2,WNT10B,GCLC,EIF5A2,TTC7A,GGH,UBAC1,FXR2,PRDX3,CCDC6,SLC25A40,AMMECR1,PLA2G15,DBI,E2F1,ACADM,HMGA1,FZD5,PLOD3,ARSB,UBE2C,DEF6,JARID2,TLL2 |
| 1.660e-02 | -4.10 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | molecular function | GO:0016818 | 808 | 142 | 16491 | 2452 |
ATP8A1,KLC2,TAP1,SMARCAL1,DHX8,PHOSPHO1,KIF2C,SEPT4,KIF26A,PICK1,ABCD4,RAB15,HELZ2,ENTPD4,DNAH6,ARL1,PSMC2,ATP13A3,ABCA2,DNM2,TUBG1,RAB20,KIF22,MYH14,DDX59,TUBA4A,ATL1,SMARCA2,KIFC2,ARHGDIB,KIF13A,ARFRP1,PIF1,RHEB,VCP,RAB2B,GINS4,ARF4,ENPP1,DNM1L,DOLPP1,ATP7B,PPP2R4,ARF6,RAP1GAP,PSMC1,RRAGD,DDX58,RECQL,PEX6,ABCG2,RAB23,ATP6V1E2,KIF23,RAB6A,MYO5C,RAC2,ATP5H,KIF13B,PCYOX1,MSH2,SRP54,DNAI1,ABCC1,KIF20A,KIF20B,ATP8B3,GNA11,DCP2,RHOB,DHX32,GNAS,NUDT16,RAB31,ATP1B3,KIF12,IFIH1,KIF3C,DYNLRB1,TUBB4B,RALBP1,ATP2C2,ABCG4,MRAS,NUDT12,GNB2,APPBP2,ATP6V0B,RALB,KIF14,ARL4D,RAB27B,MX1,ENPP4,MYO5B,FIGNL1,VPS4B,KIF1C,ATP1B1,RAD17,RAB38,ATP10D,ATP13A2,TAPBP,IDE,ATP1A1,ACYP1,CANT1,XRCC3,RAB29,ABCA1,SHPRH,ATP9A,GNAL,ERCC6L,ARL4C,DNAH3,IFT27,RND1,DIRAS3,KIF5B,TOP2A,GNB5,GTF2F2,KLC3,ATP8B1,ABCD1,ERCC2,MSH6,ATP2B1,MYO5A,RAB3B,RHOA,LONRF3,KIF11,DDX23,RND3,ABCB1,CENPE,ATP6V1C1,GEM,ABCG1 |
| 1.660e-02 | -4.10 | soft_tissue-fibrous_tissue_and_uncertain_origin-endometrial_stromal_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-endometrial_stromal_sarcoma | 24 | 8 | 17775 | 2585 |
SS18,CTNNB1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 1.660e-02 | -4.10 | phyllodes_tumour | COSMIC cancer mutations | phyllodes_tumour | 24 | 8 | 17775 | 2585 |
RB1,NF2,CTNNB1,AKT1,RET,PIK3CA,TP53,EGFR |
| 1.660e-02 | -4.10 | endometrial_stromal_sarcoma | COSMIC cancer mutations | endometrial_stromal_sarcoma | 24 | 8 | 17775 | 2585 |
SS18,CTNNB1,FGFR2,PTEN,PIK3CA,TP53,ERBB2,EGFR |
| 1.660e-02 | -4.10 | skin-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-benign_melanocytic_nevus-Spitz | 24 | 8 | 17775 | 2585 |
KIF5B,CEP89,TP53,GNA11,HLA-A,MYO5A,LMNA,EGFR |
| 1.660e-02 | -4.10 | breast-other-phyllodes_tumour | COSMIC cancer mutations | breast-other-phyllodes_tumour | 24 | 8 | 17775 | 2585 |
RB1,NF2,CTNNB1,AKT1,RET,PIK3CA,TP53,EGFR |
| 1.661e-02 | -4.10 | Aldedh | pfam domains | PF00171 | 19 | 7 | 16629 | 2504 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 1.661e-02 | -4.10 | PAS | pfam domains | PF00989 | 19 | 7 | 16629 | 2504 |
AHRR,NCOA3,ARNT2,EPAS1,AHR,ARNT,NCOA2 |
| 1.663e-02 | -4.10 | GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP | 185 | 38 | 17758 | 2588 |
GLIS3,LZTFL1,DYNLRB1,CMAS,ARMCX3,TRIM24,CAMKK1,TRAF2,MMADHC,ABCG2,SNN,CEP97,AP1M2,RALGPS2,PTEN,TACC2,RFX5,RCAN3,NTN1,TIAM1,KCTD3,CTH,CDKN2AIP,RAB3B,TMEM68,OSTM1,PCBP3,MCFD2,TP53INP2,SCARB2,RAP2C,PKD2,PRIMA1,MAP3K5,ZBTB33,CYBRD1,NXT2,USP43 |
| 1.663e-02 | -4.10 | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP | MSigDB lists | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP | 185 | 38 | 17758 | 2588 |
ARHGAP11A,SPRED1,NQO1,CIT,APOO,OSGIN2,GPSM2,SLC9A2,MAGOHB,TOP2A,CDKN2C,FAM111A,WEE1,CCNA2,CENPJ,NEK2,PLK4,GOT1,CRTAP,SNX7,METAP2,ZWINT,LAP3,MBNL3,MYBL2,CKAP2L,KIF20B,NUSAP1,CDCA2,CDC25C,MID1IP1,UAP1,HNRNPH2,AURKA,XRCC3,STK39,UBE2C,E2F8 |
| 1.664e-02 | -4.10 | GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP | MSigDB lists | GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP | 162 | 34 | 17758 | 2588 |
NCKAP5,MRC2,PINK1,ST13,FRMD4A,FLYWCH2,ABCG2,RNF182,BCL2L1,FAM46C,SPTB,MARCH8,SESN3,ANK1,GPC3,FBXO7,ZDHHC23,KANK2,ESPN,GPR161,PFKFB2,RNF11,MBNL3,BNIP3L,STRADB,TNS1,SLC25A5,RAB2B,FECH,MATN2,SLC4A3,ADIPOR1,EFNA1,RAP1GAP |
| 1.667e-02 | -4.09 | TUBA1A (tubulin, alpha 1a) | protein interactions | 7846 | 197 | 43 | 16036 | 2547 |
TAOK2,FAF2,PINK1,TUBB4B,PRKAA1,TP53,CCNJL,DNAJB11,MORF4L2,FBXO6,PKN1,HDAC6,LGALS3BP,PSMD1,CTNNB1,PTEN,TUBG1,SYK,TUBA4A,MX1,PLK1,KLK5,PLAUR,DUSP23,CDC20,IGSF8,AURKB,CBL,ANTXR1,DAG1,SMN1,EGFR,MAGED2,MDK,BTG1,NAAA,MAP2,HTT,PPP2R4,FAM110C,STARD13,CD81,CTDSP1 |
| 1.667e-02 | -4.09 | PX | prosite domains | PS50195 | 46 | 13 | 11866 | 1802 |
SNX8,SNX13,SNX18,SGK3,SNX16,PLD2,PIK3C2B,PLD1,SNX9,SNX10,SNX12,SNX30,SNX7 |
| 1.668e-02 | -4.09 | FILAMIN_REPEAT | prosite domains | PS50194 | 11 | 5 | 11866 | 1802 |
TRIM3,TRIM2,AREL1,KDELC2,TRIM45 |
| 1.668e-02 | -4.09 | PNT | prosite domains | PS51433 | 11 | 5 | 11866 | 1802 |
ETS2,ETV7,ETS1,ELF5,ELF3 |
| 1.668e-02 | -4.09 | THIOL_PROTEASE_HIS | prosite domains | PS00639 | 11 | 5 | 11866 | 1802 |
CTSL,TINAGL1,CTSC,CTSB,CTSV |
| 1.668e-02 | -4.09 | positive regulation of neurogenesis | biological process | GO:0050769 | 349 | 67 | 16441 | 2455 |
FOXO6,RET,EPHA4,CAMK1D,GRM5,TP73,CTNNB1,CDKL5,IL6ST,SMO,BCL6,DAB2IP,PACSIN1,TIAM1,TIMP2,RHEB,ARHGAP35,IRX3,DPYSL3,FYN,GPRC5B,BHLHB9,PTK7,LIMK1,EFNA5,NRG1,ITPKA,RGS14,COBL,BIN1,GRN,SERPINE2,ETV5,CRABP2,BMP2,ITGA3,GATA2,BMP7,MEGF8,PRKCI,TNFRSF12A,NPTN,NTN1,WNT3A,FAM134C,TLE6,RIMS2,HES1,TGIF1,RHOA,MMD,ASPM,RAPGEF2,HMG20B,KIF20B,ILK,MAP1B,SEMA4D,CSF1,TMEM30A,GPER1,SOX8,SHOX2,SEMA3A,ARSB,L1CAM,FOXA1 |
| 1.669e-02 | -4.09 | calmodulin-dependent protein kinase activity | molecular function | GO:0004683 | 28 | 9 | 16491 | 2452 |
MAPKAPK2,MAPKAPK3,CAMKK1,DAPK1,CAMK1D,PHKA2,ITPKA,PHKG2,CAMK2G |
| 1.675e-02 | -4.09 | HUANG_GATA2_TARGETS_UP | MSigDB lists | HUANG_GATA2_TARGETS_UP | 145 | 31 | 17758 | 2588 |
TGIF1,PAX6,HLA-E,DAP,NDRG1,SAT1,EMP3,KCTD12,TGFBR1,RAB38,MGST2,SH3KBP1,CMTM7,GABARAPL1,BTG1,KCNN4,SIPA1L1,CST3,SLC2A6,FUT8,RIN3,RAB31,CDKN1B,FAM117A,IL17RA,H2AFY,ACADM,DGKG,TPCN1,GAB1,MYL12B |
| 1.678e-02 | -4.09 | ROVERSI_GLIOMA_COPY_NUMBER_UP | MSigDB lists | ROVERSI_GLIOMA_COPY_NUMBER_UP | 95 | 22 | 17758 | 2588 |
SYPL1,DDB2,BCAM,LRP4,NUB1,SLC35C1,GALNT7,MAPK8IP1,RHEB,CKAP5,MDK,PRKAG2,PTPRJ,PVRL2,FOSB,MADD,KLC3,TSPAN13,CRY2,ERCC2,SYT13,AHR |
| 1.678e-02 | -4.09 | BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | 95 | 22 | 17758 | 2588 |
SLC25A24,ARMCX3,PLSCR1,IFITM3,STAT4,RASGRP3,PLA2G16,FAM46C,ALCAM,IL18R1,EPCAM,B3GALNT1,WIPI1,OSBPL3,CD9,GRAMD1C,PLIN3,F2R,HOOK1,F2RL1,CPE,XDH |
| 1.680e-02 | -4.09 | MURATA_VIRULENCE_OF_H_PILORI | MSigDB lists | MURATA_VIRULENCE_OF_H_PILORI | 24 | 8 | 17758 | 2588 |
COL6A2,SOX9,COL6A1,SOD2,BCL6,CTTN,TMPRSS4,L1CAM |
| 1.680e-02 | -4.09 | VALK_AML_CLUSTER_8 | MSigDB lists | VALK_AML_CLUSTER_8 | 24 | 8 | 17758 | 2588 |
FECH,BCAM,ANK1,CDH1,ABCG2,TNS1,TRAK2,OPTN |
| 1.680e-02 | -4.09 | TOMIDA_METASTASIS_UP | MSigDB lists | TOMIDA_METASTASIS_UP | 24 | 8 | 17758 | 2588 |
GNAS,PTTG1,TFAP2A,DNER,CKAP4,METAP2,TUBA4A,IER3 |
| 1.681e-02 | -4.09 | immunological synapse | cellular component | GO:0001772 | 33 | 10 | 17570 | 2579 |
PTPRJ,LGALS3,DLG1,EZR,PRKCQ,CD81,ALCAM,ICAM1,BCL10,PRKAR1A |
| 1.681e-02 | -4.09 | PID_ERBB4_PATHWAY | MSigDB lists | PID_ERBB4_PATHWAY | 38 | 11 | 17758 | 2588 |
ADAM17,FYN,ITCH,LRIG1,PIK3R1,PIK3CA,NRG2,ERBB2,NRG1,WWP1,PIK3CD |
| 1.681e-02 | -4.09 | VALK_AML_WITH_FLT3_ITD | MSigDB lists | VALK_AML_WITH_FLT3_ITD | 38 | 11 | 17758 | 2588 |
KCNK5,HOXA9,LYRM1,PBX3,COL4A5,PIM1,SEPP1,IL1RAP,HOXB2,LGALS3BP,SMC4 |
| 1.681e-02 | -4.09 | BIOCARTA_FCER1_PATHWAY | MSigDB lists | BIOCARTA_FCER1_PATHWAY | 38 | 11 | 17758 | 2588 |
PLA2G4A,CALM2,PLCG1,PAK2,CALM1,PIK3R1,PIK3CA,CALM3,ELK1,FOS,SYK |
| 1.683e-02 | -4.08 | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | 117 | 26 | 17758 | 2588 |
PCOLCE,ARHGEF11,TEF,CYP2J2,SERPINB9,EMP3,ARHGDIB,LPIN3,DDR1,CASP4,SH3KBP1,LGALS3BP,PRICKLE3,COL6A1,CAPG,ARAP1,CAB39,TRIM21,DAB2IP,IFIT1,FHL1,AKNA,SNX10,OSGIN1,DMPK,XDH |
| 1.685e-02 | -4.08 | Cysteine Metabolism | SMPDB pathways | SMP00013 | 9 | 5 | 978 | 190 |
GOT1,GCLM,CTNS,GCLC,CTH |
| 1.685e-02 | -4.08 | Cystinosis- ocular nonnephropathic | SMPDB pathways | SMP00722 | 9 | 5 | 978 | 190 |
GCLM,GOT1,CTNS,GCLC,CTH |
| 1.685e-02 | -4.08 | Beta-mercaptolactate-cysteine disulfiduria | SMPDB pathways | SMP00499 | 9 | 5 | 978 | 190 |
GOT1,GCLM,CTNS,GCLC,CTH |
| 1.687e-02 | -4.08 | V$E2F_Q4_01 | MSigDB lists | V$E2F_Q4_01 | 226 | 45 | 17758 | 2588 |
ARHGAP11A,IER5L,GATA3,NRP2,WEE1,E2F7,PCNA,ZNF687,FAM160A2,DPYSL2,BMP7,RANBP1,PLK4,TNPO2,MXD3,KNTC1,STT3B,CITED2,OSBPL7,ETV4,TIAM1,UFD1L,DDB2,ADAMTS2,UXT,FBXO9,PKMYT1,ERBB2IP,KDM3A,PRIM1,GPRC5B,DCK,HOXA9,ZNF367,E2F1,AGFG2,SFMBT1,KLF5,HMGA1,WDR62,GEN1,CBX5,NR3C2,E2F8,MELK |
| 1.690e-02 | -4.08 | pituitary-craniopharyngeal_duct-craniopharyngioma-papillary | COSMIC cancer mutations | pituitary-craniopharyngeal_duct-craniopharyngioma-papillary | 53 | 14 | 17775 | 2585 |
ADAMTS2,TAOK2,CTNNB1,HTT,PELI2,DNAJC3,DUSP23,CCM2,UTRN,EPHX4,KIF1C,PDK3,ARF6,RSAD1 |
| 1.690e-02 | -4.08 | smooth_muscle | COSMIC cancer mutations | smooth_muscle | 53 | 14 | 17775 | 2585 |
GNAS,CDKN2C,RB1,SS18,CTNNB1,CDH1,JAK1,AKT1,PTEN,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 1.692e-02 | -4.08 | GGTGTGT,MIR-329 | MSigDB lists | GGTGTGT,MIR-329 | 106 | 24 | 17758 | 2588 |
THRB,PCGF5,NRBF2,GGA1,BCL9,RNF165,CLSTN1,PDE5A,BLCAP,FXR2,PRR7,DPYSL3,KLHL2,IRF2BPL,WDFY1,KLF12,IL6ST,FOSB,N4BP3,DAPK1,NRG1,PDE4D,SLC39A10,MYT1 |
| 1.692e-02 | -4.08 | REACTOME_G1_S_TRANSITION | MSigDB lists | REACTOME_G1_S_TRANSITION | 106 | 24 | 17758 | 2588 |
CCNE2,PSMB4,PSME2,PSMD7,CUL1,PSMD10,PSME1,PKMYT1,CCNB1,CDK1,PSMA4,PRIM1,RB1,WEE1,PCNA,PSMD1,CCNA2,PSMD3,PSMC2,E2F1,CDKN1B,CKS1B,PSMC1,PSMA5 |
| 1.692e-02 | -4.08 | V$EN1_01 | MSigDB lists | V$EN1_01 | 106 | 24 | 17758 | 2588 |
CD55,PAX6,GRHL2,SAT1,IRX4,MORF4L2,SAV1,FNDC3A,RAB2B,NEO1,KDM4D,FOXP2,TTC12,GPC3,PEX2,SIPA1L1,FIBCD1,MITF,NR4A3,NRG1,SH3BGRL2,FHL1,MAP3K5,OSR1 |
| 1.692e-02 | -4.08 | LIM_MAMMARY_LUMINAL_MATURE_UP | MSigDB lists | LIM_MAMMARY_LUMINAL_MATURE_UP | 106 | 24 | 17758 | 2588 |
PLEKHG3,PVRL4,SORT1,HDAC11,GMPR,IL13RA1,SLC7A2,TP53INP2,ALCAM,HOXB2,CCDC92,ALDH3B1,MLPH,FAAH,FAM63A,DUSP10,TUBG1,TSPAN13,TMEM8A,TSPAN1,SULT2B1,SLC16A5,FOXA1,PROM2 |
| 1.692e-02 | -4.08 | GSE11924_TFH_VS_TH2_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH2_CD4_TCELL_UP | 191 | 39 | 17758 | 2588 |
UNKL,ARHGEF7,TRAF2,C6orf106,BLCAP,CCNL1,PDXDC1,ZNF687,RPS6KA2,TMEM87B,RALGPS2,CYP2S1,PPME1,BAX,AKR1B1,SLC16A5,MPHOSPH9,HP1BP3,PHF20L1,PAPD7,RC3H2,SLC35C1,SCRIB,KIF13A,KIAA1109,CAPNS1,FXR2,SNAPC2,FAS,RASGRP2,HLA-B,ATXN7L3,NMI,ARAP1,MAP3K11,RBM43,CCDC97,TMEM173,FBXW5 |
| 1.692e-02 | -4.08 | GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP | 191 | 39 | 17758 | 2588 |
DYRK3,CENPI,DGKQ,ETV5,SOD2,MGST2,TRIB2,FAM101B,PSIP1,CYP26A1,FANCI,MESDC2,PAK6,RB1,CTGF,CDH1,ZNF823,REEP1,CD9,DRAM1,GYS1,ALDH7A1,ALS2CL,RBMS2,P2RX4,PFKFB2,FBXO9,EZR,PDK3,GTF2A2,B3GALNT2,ARSK,CASP4,OPTN,IRX3,COQ10A,TWSG1,SERPINB6,CHPT1 |
| 1.692e-02 | -4.08 | GSE3982_NEUTROPHIL_VS_TH1_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH1_DN | 191 | 39 | 17758 | 2588 |
ZNF395,FOXM1,NUAK1,CKAP2,PTTG1,PSMD7,C6orf106,GTF3A,NENF,PHLDA1,SPSB1,RCN1,WEE1,OSBPL3,PASK,NEK2,CKS1B,ERCC2,MANF,GFI1,CKS2,METAP2,TDP1,ESYT1,GTF2A2,BORA,FANCE,PSMA4,DAG1,PAFAH1B3,DDOST,NEIL3,LRIG1,PRPS2,AKIP1,CD81,C17orf75,RUSC1,USP16 |
| 1.692e-02 | -4.08 | KYNG_DNA_DAMAGE_DN | MSigDB lists | KYNG_DNA_DAMAGE_DN | 191 | 39 | 17758 | 2588 |
CCNC,SERPINE2,NDRG1,HEXB,FLOT1,PDGFRL,RAB6A,TP53I11,PRKACA,EFNB1,NRP2,CCND1,BTG3,PCNA,CCNA2,ITGB8,CTGF,DLG1,IRF2,SGCB,IL10RB,FAM69A,SEMA3B,SNX8,SOD1,PTPN18,PRSS23,PTGER4,BNIP3L,RHOB,PRDX4,PAFAH1B3,NGFRAP1,SEMA4D,RBL1,TLE1,CAB39,SERPINB6,SLC31A2 |
| 1.692e-02 | -4.08 | GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP | 191 | 39 | 17758 | 2588 |
FRMD4A,IBTK,PARP14,NDRG1,SOD2,FAM91A1,SLC25A36,ZFYVE16,ACAP2,USP1,CASD1,RASGRP1,NCOA2,SMC4,PARP9,CLCN3,CXXC5,VPS4B,ACO1,DBR1,COX11,FBXO9,BCL2L13,RAB2B,G2E3,TMEM50B,CDCA4,BHLHB9,SLC35B3,PAPD5,NAB2,APPL2,SPCS3,HOOK1,HIPK3,CXorf56,JARID2,RAD21,TMEM131 |
| 1.692e-02 | -4.08 | GSE17721_POLYIC_VS_CPG_24H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_24H_BMDM_UP | 191 | 39 | 17758 | 2588 |
IL15RA,ST14,HEBP1,RASA2,TRAF2,SYTL4,SNN,PLA2G16,MERTK,FGF19,GBX2,SESN3,ADD3,OXCT1,TAX1BP3,IRF2,GOT1,CNOT6L,SCN3A,WNT10B,MPP1,BCL9,SHARPIN,CBX6,GGH,SAV1,RNPEP,SPTLC2,NFIX,CCDC6,MATN2,ARRDC1,CHMP4B,LRRK1,RELL1,RBM43,USF2,MYL12B,TMEM131 |
| 1.692e-02 | -4.08 | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP | 191 | 39 | 17758 | 2588 |
ENO2,GALNT12,ITGA6,GATA3,TRIB2,NUCB2,C11orf95,ETS1,IL18R1,DENND2D,LTBP3,TGFBR3,MGAT4A,PASK,DDHD2,MSH2,FAM102A,MYBL1,COL6A2,SYNE2,RUNX3,PRKCQ,YES1,ITPR3,PLEKHB1,PRIM1,CD8A,PLCG1,ALDH5A1,LDLRAP1,LRIG1,AMMECR1,INPP4B,SERPINI1,FHL1,TBC1D4,TRAF5,NR3C2,DOCK9 |
| 1.692e-02 | -4.08 | GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN | 191 | 39 | 17758 | 2588 |
CDK17,MRPL44,FARP1,IBTK,SLC25A13,MORF4L2,PIGL,TM9SF2,PAK2,PLK4,KIF22,RFX5,FAIM,CASD1,TIAM1,METAP2,CLCN3,TAF5,MLEC,ASXL1,RAPGEF2,CDC20,VAMP3,CCDC34,AURKB,DUSP4,SAV1,CDK1,FRMD4B,PRIM1,KDSR,SLC25A4,CCDC6,CDCA5,ITPR1,PPM1H,SPCS3,ARF6,SRSF9 |
| 1.692e-02 | -4.08 | GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDM_DN | 191 | 39 | 17758 | 2588 |
ARMCX3,TUBB4B,RUSC2,MAN1A2,NDRG1,SERPINB9,DGKA,UBE2Z,PSMD10,P2RX7,PLXNA1,GPSM2,KREMEN1,CYP39A1,ICAM1,EPDR1,M6PR,ATP6V0B,VASP,ARL1,KLF3,MDFIC,RASGRP1,HPS3,RIPK2,NR3C1,TBC1D8B,RNF11,SERTAD3,GRIN1,VWA1,CALCRL,TAPBP,RBL1,NFKBIA,TDRD7,GEM,B4GALT3,ST3GAL1 |
| 1.692e-02 | -4.08 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_UP | 191 | 39 | 17758 | 2588 |
MRPS9,TTC8,NUDT6,PACSIN2,FRMD4A,NF2,CHCHD7,PLEKHJ1,SHPRH,ASL,FAM78A,IFT27,ADD3,METTL7A,PPP4R1,PCYOX1,TUBG1,SGK1,RCAN3,PXMP4,TIAM1,TTLL1,PTPN9,PIK3R1,COX11,SCRIB,ICMT,GNA11,GLCE,TMEM164,ZNF641,FA2H,KIAA0141,SLC9A6,MADD,PRPS2,EIF4EBP2,ATMIN,ACOT7 |
| 1.692e-02 | -4.08 | GSE17721_0.5H_VS_24H_POLYIC_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_24H_POLYIC_BMDM_UP | 191 | 39 | 17758 | 2588 |
ANXA3,AVPI1,HEBP1,SUZ12,DNAJC3,DNAJB11,NDRG2,GDF15,FAM81A,SEPP1,STIL,CCNA2,CD22,DAPK1,OPN3,AKR1B1,TNFRSF18,PHKG2,NUP85,POU6F1,SHMT1,GUSB,UXT,CDC20,MYBL2,FURIN,NUBP1,SESN1,C4orf27,DAG1,PGF,FGFR2,MMP17,CGREF1,NKD1,PRIMA1,CD81,MAFF,SRSF9 |
| 1.693e-02 | -4.08 | CCAATNNSNNNGCG_UNKNOWN | MSigDB lists | CCAATNNSNNNGCG_UNKNOWN | 58 | 15 | 17758 | 2588 |
SAP130,HES1,PCNA,NKX3-1,PSRC1,PAX6,UPF3B,PPP1R10,HOXA9,IL6ST,PEX2,LMAN1,FAR1,APC2,DNAJB9 |
| 1.693e-02 | -4.08 | PID_FAK_PATHWAY | MSigDB lists | PID_FAK_PATHWAY | 58 | 15 | 17758 | 2588 |
CAPN2,CCND1,PLCG1,FYN,RHOA,ARHGEF11,ARHGEF7,PIK3R1,PIK3CA,ITGAV,YES1,BCAR1,ETS1,RASA1,ARHGAP35 |
| 1.693e-02 | -4.08 | PID_SHP2_PATHWAY | MSigDB lists | PID_SHP2_PATHWAY | 58 | 15 | 17758 | 2588 |
RHOA,JAK1,IGF1R,LMO4,IL6ST,PIK3R1,STAT1,PIK3CA,PDGFB,PRKACA,JAK3,GAB1,EGFR,FRS3,ARHGAP35 |
| 1.695e-02 | -4.08 | human chr6p21 | chromosome location | human chr6p21 | 32 | 8 | 26250 | 2805 |
RUNX2,STK38,KCNK5,ZSCAN12,HMGA1,ITPR3,ETV7,MDFI |
| 1.695e-02 | -4.08 | FOXM1 transcription factor network | Pathway Interaction DB | foxm1pathway | 37 | 14 | 2227 | 480 |
PLK1,CCND1,ONECUT1,RB1,CENPA,FOXM1,ETV5,NEK2,CKS1B,AURKB,CCNB1,CCNB2,FOS,CDK1 |
| 1.698e-02 | -4.08 | sensory organ development | biological process | GO:0007423 | 499 | 92 | 16441 | 2455 |
PAX6,GRHL2,NF2,RET,MCOLN3,GATA3,ERBB2,OSR2,TMC1,SLC9A3R2,PLS3,RCN1,CYP1A1,CTNNB1,ALDH1A3,MITF,DLG1,CDKN1B,TWIST1,ECE1,DVL2,CYP1B1,SOD1,FZD4,PRKRA,CLCN2,ABR,ARHGAP35,HSF4,BFSP1,PTK7,TBX1,TRAF3IP1,NKD1,LRIG1,TDRD7,HDAC1,HOXC13,CTHRC1,USH1C,CDKN1C,SDC4,CCM2,SOX9,SLC25A27,NES,TGFBR1,JAG2,PLPPR4,MERTK,SIX4,PPP2R3A,FZD6,GBX2,BMP2,MDM1,GATA2,BMP7,CST3,FJX1,BAX,PRKCI,TFAP2A,ATP8B1,NTN1,WNT3A,GFI1,SPRY2,RPGR,HES1,TGIF1,WNT10B,DCHS1,SCRIB,UNC45B,BCAR3,MAPKAPK2,PITX2,PROM1,CTNS,FAT4,ACVRL1,FGFR2,TWSG1,TBX18,NR4A3,GDF11,FZD5,SOX8,OSR1,SHROOM2,RARG |
| 1.700e-02 | -4.07 | endoplasmic reticulum unfolded protein response | biological process | GO:0030968 | 109 | 25 | 16441 | 2455 |
GFPT1,SEC61B,HSP90B1,ADD1,SEC61G,DNAJC3,AMFR,ERO1A,PDIA5,DNAJB11,KDELR3,VCP,DNAJB9,LMNA,CCND1,CALR,WIPI1,WFS1,BAX,DAB2IP,YOD1,MYDGF,PDIA6,CTDSP2,CTH |
| 1.701e-02 | -4.07 | myeloid cell differentiation | biological process | GO:0030099 | 198 | 41 | 16441 | 2455 |
CASP3,KLF2,DYRK3,ADD1,CDKN1C,HOXB7,EPAS1,THRA,GATA3,TNFSF9,CD109,RB1,TGFBR3,CTNNB1,FAM20C,GATA2,GPC3,MITF,IL31RA,BCL6,PIK3CD,ERCC2,SNX10,FARP2,OSTM1,DMTN,CASP9,NFE2L1,SLC11A2,GLO1,EIF2AK1,SFXN1,FECH,PRDX3,DHRS2,CSF1,PTBP3,LRRK1,F2RL1,SLC25A38,JAK3 |
| 1.702e-02 | -4.07 | Signaling by EGFRvIII in Cancer | REACTOME pathways | R-HSA-5637812 | 15 | 6 | 8202 | 1235 |
PLCG1,CBL,GAB1,EGFR,PIK3R1,PIK3CA |
| 1.702e-02 | -4.07 | Depolymerisation of the Nuclear Lamina | REACTOME pathways | R-HSA-4419969 | 15 | 6 | 8202 | 1235 |
LEMD2,LPIN3,CCNB1,CNEP1R1,CDK1,LMNA |
| 1.702e-02 | -4.07 | Constitutive Signaling by EGFRvIII | REACTOME pathways | R-HSA-5637810 | 15 | 6 | 8202 | 1235 |
PLCG1,CBL,GAB1,EGFR,PIK3R1,PIK3CA |
| 1.702e-02 | -4.07 | MHC_I-like_Ag-recog | interpro domains | IPR011161 | 24 | 8 | 18293 | 2672 |
HLA-B,MICB,HLA-E,HLA-F,RAET1L,HLA-C,ULBP2,HLA-A |
| 1.703e-02 | -4.07 | IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR | 511 | 92 | 17758 | 2588 |
CCNC,SPC25,SSH1,TMX4,DHX8,UBE2Q1,FTH1,NUF2,IL13RA1,COMMD5,OAT,CCNB1,TMEM19,ELMOD2,NAPG,ATP6V0B,FAM46A,P4HB,REEP1,ANKRD12,TACSTD2,NFU1,MINPP1,LMAN1,SNX8,TMEM43,FIGNL1,AGPS,OSTM1,PBK,SAT1,COX11,MGAM,CKAP2L,PRKAR2B,SAV1,IDH1,LHFPL2,ABR,NIN,HPSE,SIPA1L1,ARRDC1,SP6,PIEZO1,LTA4H,SLC31A2,PSMC1,ANXA3,DAP,CTSB,ELOVL7,BLVRB,SELL,GMCL1,NUCB2,PSIP1,BMP2K,AIM1L,CTSC,SGK3,DRAM1,FNIP1,SORL1,OSTF1,HSPA13,NPTN,MAPK7,RAG1,ALDH3A2,SLC45A3,TSPAN33,EEF1D,TMED2,RHOA,ERMAP,TACC1,SPTLC2,C4orf27,NFIB,PLIN5,TMEM50B,RGS9,SEMA4D,PRDX3,TADA2B,RAB31,PIAS2,ATP6V1C1,NCAPG2,ESPL1,CD33 |
| 1.704e-02 | -4.07 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | biological process | GO:0051437 | 72 | 18 | 16441 | 2455 |
PLK1,PSMB4,PSME2,CDC20,PSMD7,CUL1,PSMD10,PSME1,CCNB1,PSMA4,CDK1,PSMD1,PTEN,PSMD3,PSMC2,UBE2C,PSMC1,PSMA5 |
| 1.706e-02 | -4.07 | Hurthle_cell_carcinoma | COSMIC cancer mutations | Hurthle_cell_carcinoma | 209 | 42 | 17775 | 2585 |
TRIM24,TTC39B,ATP8A1,PYROXD2,RET,TP53,AKAP17A,PLD2,SBF1,KTN1,CTNNB1,CDH1,PTEN,MSH2,PIK3CA,FNIP1,CACNA1D,MYH14,PANX2,TFG,KANK3,ABCC1,MYO5B,SPATA20,AKT1,SEPT6,SLC35C1,ERBB2IP,BCL2L13,IDH1,TRUB1,EGFR,PRDM11,GNAS,GABRD,CCNB3,SYT7,RCBTB2,CCDC6,ARHGAP4,UBE2C,PRKAR1A |
| 1.706e-02 | -4.07 | thyroid-carcinoma-Hurthle_cell_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-Hurthle_cell_carcinoma | 209 | 42 | 17775 | 2585 |
TRIM24,TTC39B,ATP8A1,PYROXD2,RET,TP53,AKAP17A,PLD2,SBF1,KTN1,CTNNB1,CDH1,PTEN,MSH2,PIK3CA,FNIP1,CACNA1D,MYH14,PANX2,TFG,KANK3,ABCC1,MYO5B,SPATA20,AKT1,SEPT6,SLC35C1,ERBB2IP,BCL2L13,IDH1,TRUB1,EGFR,PRDM11,GNAS,GABRD,CCNB3,SYT7,RCBTB2,CCDC6,ARHGAP4,UBE2C,PRKAR1A |
| 1.707e-02 | -4.07 | uDENN | pfam domains | PF03456 | 15 | 6 | 16629 | 2504 |
ST5,SBF1,DENND1B,DENND2D,MADD,DENND5B |
| 1.708e-02 | -4.07 | negative regulation of small GTPase mediated signal transduction | biological process | GO:0051058 | 42 | 12 | 16441 | 2455 |
ARHGAP24,TNK1,TIMP2,ARAP3,ITGA3,RASA2,BCL6,STMN3,DAB2IP,SPRY2,RASA1,ARHGAP35 |
| 1.709e-02 | -4.07 | - | gene3d domains | 3.40.720.10 | 31 | 10 | 9988 | 1574 |
ENPP4,GNS,ENPP1,ALPP,ARSG,GALNS,ENPP5,ARSB,ARSK,SULF2 |
| 1.709e-02 | -4.07 | WALLACE_PROSTATE_CANCER_RACE_DN | MSigDB lists | WALLACE_PROSTATE_CANCER_RACE_DN | 79 | 19 | 17758 | 2588 |
ENPP4,TRIM2,MARK1,NQO1,LGALS8,VANGL1,PYGL,EIF2AK1,MEST,USP6,PLOD2,PTK7,PIK3CA,CSGALNACT1,TLE1,LIMCH1,OCLN,PKIA,FAM134B |
| 1.714e-02 | -4.07 | regulation of platelet activation | biological process | GO:0010543 | 28 | 9 | 16441 | 2455 |
PDGFA,SERPINE2,DMTN,UBASH3B,PRKG1,PRKCQ,TEC,PDGFB,SYK |
| 1.714e-02 | -4.07 | metanephros morphogenesis | biological process | GO:0003338 | 28 | 9 | 16441 | 2455 |
HES1,LGR4,CTNNB1,FMN1,FRAS1,SOX9,SMO,PKD2,SOX8 |
| 1.714e-02 | -4.07 | negative regulation of lymphocyte apoptotic process | biological process | GO:0070229 | 28 | 9 | 16441 | 2455 |
IRS2,TSC22D3,BCL6,PRKCQ,AURKB,SLC39A10,RAG1,JAK3,BCL10 |
| 1.714e-02 | -4.07 | negative regulation of TOR signaling | biological process | GO:0032007 | 28 | 9 | 16441 | 2455 |
PRKAA2,SIRT1,TSC1,NUAK1,PRKAA1,SH3BP4,FNIP1,TNFAIP8L1,EPM2A |
| 1.716e-02 | -4.07 | pyridoxal phosphate binding | molecular function | GO:0030170 | 52 | 14 | 16491 | 2452 |
MARC1,SHMT1,GCAT,SRR,CCBL2,PYGL,GOT1,PDXK,OAT,GAD1,SPTLC2,PDXDC1,CTH,SGPL1 |
| 1.718e-02 | -4.06 | GSE20715_0H_VS_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_DN | 197 | 40 | 17758 | 2588 |
CCNE2,GCLM,SPC25,DHX8,SPSB1,PHLDA1,TNFSF9,DNAJB9,ELF3,TOP2A,SPP1,CCNA2,TIMP1,PPP1R10,RANBP1,DAPK1,PRC1,BUB1,MXD3,MANF,WBP5,CENPA,MLEC,SEC61B,KIF20A,GCLC,PBK,NUSAP1,ANLN,MAP3K6,CDK1,SOCS3,PRIM1,PTGS2,RBM47,AREG,CLIP4,SPCS3,UBE2C,HSPB1 |
| 1.720e-02 | -4.06 | LEE_LIVER_CANCER_MYC_UP | MSigDB lists | LEE_LIVER_CANCER_MYC_UP | 53 | 14 | 17758 | 2588 |
PDGFC,RPL12,CTGF,KIF20A,CYR61,RALB,CDCA3,HTATIP2,NUSAP1,SNTB1,CDK1,CSRP2,CYP26A1,DMPK |
| 1.720e-02 | -4.06 | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | MSigDB lists | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | 53 | 14 | 17758 | 2588 |
CCNE2,PSMD1,PSMB4,PSME2,PSMD3,PSMC2,TP53,PSMD7,CDKN1B,PSMD10,PSME1,PSMC1,PSMA4,PSMA5 |
| 1.720e-02 | -4.06 | KEGG_GLYCEROLIPID_METABOLISM | MSigDB lists | KEGG_GLYCEROLIPID_METABOLISM | 43 | 12 | 17758 | 2588 |
DGKH,ALDH2,AGPAT2,DGKQ,DGKA,DGAT2,AKR1B1,ALDH7A1,GLA,DGKG,ALDH3A2,DGKE |
| 1.720e-02 | -4.06 | PID_THROMBIN_PAR1_PATHWAY | MSigDB lists | PID_THROMBIN_PAR1_PATHWAY | 43 | 12 | 17758 | 2588 |
ZYX,VASP,RHOA,PIK3R1,PIK3CA,DNM2,ARRB1,PKN1,F2R,PLCB2,ADRBK2,GNA11 |
| 1.720e-02 | -4.06 | YAP1_UP | MSigDB lists | YAP1_UP | 43 | 12 | 17758 | 2588 |
DDB2,FAF2,MYLK,FLOT1,RPN2,C8orf58,CDIPT,FAM167A,CXorf56,SNX7,FAM45A,CDK14 |
| 1.720e-02 | -4.06 | KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | MSigDB lists | KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | 43 | 12 | 17758 | 2588 |
IL1R1,MMD,TIMP1,ADO,EPS8,CAPG,CKAP2L,RCAN2,DUSP4,NCEH1,ANLN,F2R |
| 1.721e-02 | -4.06 | bone | COSMIC cancer mutations | bone | 8539 | 1292 | 17775 | 2585 |
HECA,FAM160B1,IBTK,GRIK2,PNPLA2,HEXB,RET,DPP8,FAM46C,SPSB1,CARD10,ZNF275,CDKN2C,NAPG,PHYHIP,PPP1CA,RNF26,WBP4,TIAM1,IL10RB,CPE,MGAT5,CCDC74A,CDA,PNKD,ABR,PLCG1,ATP7B,FAM114A1,TRAF3IP1,NOD2,RNASEL,STARD13,ANXA11,SCN5A,ITGA6,RAB23,ARHGEF35,FAM21C,HPCAL4,RABGGTA,TFAP4,FLII,FRY,PAIP2B,MEGF8,RIMS3,FBXL14,MAP3K9,SLAIN2,ALPK1,PANX2,MAPK7,ZMYM1,MOXD1,DGKG,NUP85,MCCC2,HPS3,FHL2,NPHP3,DPYSL4,SFXN5,PLIN5,CACHD1,FNTA,SLC4A4,S100A5,DGAT2,CLMN,TMEM173,RUSC1,ADAMTS16,DMPK,DOCK9,WDR63,NQO1,GRK6,FAM91A1,REPS1,RBM23,MUC16,ST5,CDH1,RASGEF1A,LRP11,MYT1,SNX10,SNX8,COL6A2,ERMP1,APOBEC3D,PTPN9,HTATIP2,XRCC6BP1,TANC1,ZNF618,EBF2,GIGYF1,CCNB3,SHROOM3,CDK19,WFS1,AXL,MAPK12,CTHRC1,HSP90B1,FAM189A2,CKAP2,ESRP1,BACE1,TRAF2,CCM2,OSGIN2,BTN3A1,CTSZ,PLPPR4,SLC25A43,NFAT5,BEX2,SLC25A45,PDCD10,FUT2,ITGB8,IGSF9,GPC3,MGAT4A,TMEM62,CST3,TUBGCP6,FAM20B,KLC3,FAM102A,RAG1,MED22,PARP9,PVRL4,ADAMTS2,TACC1,PIK3R1,MRS2,CXorf57,C4orf27,CNTNAP1,PLOD2,RAB11FIP2,SLC35B3,ITGAV,CD81,PHC1,TLL2,TMEM131,CCNI,ILDR1,BCAM,KIAA1462,ARFGEF1,NDRG2,TEX2,NENF,MGAT5B,ITPR2,SPTB,FANCI,TFAP2E,SUSD2,CPNE2,ENTPD4,NUP210,CTNNB1,RABEP2,P4HB,IL6ST,PAPSS1,TMEM143,ABCA2,PLK1,PTPN18,MARK1,KCNIP3,CELSR2,STAU2,NFE2L1,CR2,CCBL2,ARFRP1,EAF2,SESN1,DZIP1L,KDM4D,TNS4,HS6ST1,TRAM2,KCNMB4,KLF12,ARRDC1,KLF11,HS6ST3,PARP12,RUNX2,USH1C,HJURP,DNAJB2,NCKAP1,FBLN1,RSAD1,ANO1,MYO5C,B4GALNT1,TNS3,FRAS1,KIF13B,AHCY,FAR2,WNT3A,MPHOSPH9,CKAP4,USP31,BTNL9,RGMB,MGAT4B,SCRIB,PRX,NMT2,C18orf8,COL13A1,PHLPP2,NLRC5,ZDBF2,PLD1,SEMA3A,CCNB2,CDAN1,RAD21,TMX4,TP53,RHPN2,SYTL2,IER3,PDGFA,TTC21B,WDR44,TACC2,LMO4,BCL6,ZDHHC23,CDH3,GLB1L2,ESPN,NOTCH3,OAS3,TMEM64,CTDSP2,SULF2,CLCN3,AKT1,PTGER4,ACO1,C3orf33,DAG1,ATP13A2,ZNF628,IDE,PTPRJ,PAFAH1B3,RBL1,STK38,XRCC3,ARHGAP4,FAM134B,ZMAT1,BIN1,PINK1,DYRK3,CDH22,CPEB4,TAB3,KLHL13,SCD5,MCTP2,ERI2,ERCC6L,GTF3A,IL22RA1,VPS26A,PARM1,H1FX,NRP2,M6PR,CD109,FOXP2,CDK16,ALPP,IL17RA,TRIM21,ALDH7A1,HMGCL,FAM134C,ATP2B1,LRRC24,NFE2L3,FBLN5,GUSB,DPP9,MAML2,COL7A1,RNPEP,TXNDC11,BCL10,USP6,DDAH1,ICOSLG,PTGES,HIPK3,ARHGEF4,GOLGB1,FAM171B,LAMP1,SLC35D2,LGR4,HSPG2,SSH1,TSC22D3,PDGFRL,PJA2,PICK1,PAK6,CYP1A1,ANKS6,ZNF823,STIM1,OSBPL3,SERINC2,POLL,PIK3CA,KCNS3,SNX16,IRF2,TACSTD2,HYLS1,MARCH2,METAP2,ACVR1C,CDYL,SLC35C1,KIF13A,POR,SH2D3C,LRIG1,PRDM5,BMP1,MAPK13,WBSCR27,F2RL1,FGD1,SEMA6B,RECQL,MRC2,TBC1D1,APBA1,TNFRSF19,PDXDC1,SH3RF2,MESDC2,CALR,DOPEY2,RALGPS2,LYPD3,AIM1,MSH2,DAPK1,PRKG1,OSTF1,CACNA1D,DLX4,KCTD3,ZNF117,GPR161,TRAK2,SOCS5,SPATA20,GCC2,PRODH,KCNJ12,DCHS1,PYGL,WHSC1,ATP8B3,ANTXR1,NFIB,PDE11A,AP1AR,NT5C2,PLEKHH2,TJP3,FAM64A,PELI2,MATN2,MPP2,ARAP1,AGBL5,SFMBT1,CABIN1,CDK18,SAMD8,PLIN3,HOOK1,IFIH1,EHD1,MFSD3,TCF25,TCTN2,CAPN12,REPS2,GPR107,CCDC110,RALBP1,CERCAM,ATP2C2,FAM78A,FTH1,TMEM170B,TMEM19,FLT3,DDR1,ART5,CYP39A1,ZFYVE9,EPS8L2,C11orf84,APOBEC3B,TRANK1,RNASEH2A,PDE4D,TSPAN1,OSBPL7,SULT2B1,DOCK4,COG2,FOXJ2,PANK1,CLSTN1,UTRN,KIF1C,PYGO1,ATP1B1,CBL,ITPR3,ATP10D,FZD7,DDOST,ACAD10,SLC27A3,COBL,MAMDC2,PRKAR1A,PLSCR4,DEPDC1,CBLL1,HERC5,PBX3,NES,PLD2,DNAH3,EFNB1,FGF19,CKAP5,RASSF8,E2F7,FUT8,CD9,CCDC82,ERBB3,MSH6,FARP2,TGIF1,PDGFC,ARHGEF28,ALDH2,B3GNT2,LONRF3,ZC3H11A,TCFL5,ZKSCAN2,DIAPH2,C2orf69,UBAC1,YES1,FOS,CDK5RAP1,DCTN6,ACADSB,DGCR2,SEC14L4,FGFR2,RIN3,ABCB1,ERAP1,WDR62,ESPL1,MELK,RGMA,FAF2,CRYM,VARS2,PLAC1,HTR1D,ADPRHL1,ZFYVE16,SIPA1L2,CDKL5,ARHGEF37,ANKFN1,TRPC1,BTBD3,CYP1B1,ASXL1,LAP3,ACBD3,ITCH,RGAG1,MAN2A2,GPRC5B,HPSE,MADD,TDRD7,ZNF165,SP6,GLA,CHPT1,NR2C2,PCSK5,LASP1,PPP1R2,ZNF395,PPP1R12A,SERPINE2,BVES,ETV5,ASB9,ABCG2,FAM81A,ADAMTSL4,QSOX2,CES2,PFKL,COL6A1,PRKCI,SRP54,LIMCH1,C10orf54,HLA-C,SLC12A2,CCDC88A,SNED1,ELK3,PODXL2,PDE5A,KIAA1109,NUBP1,C3orf58,STEAP1,MFSD7,RANBP9,INSR,TMEM30A,SPAG7,SH3BP4,JAK3,TOB1,COL16A1,RARG,AFAP1,SNX30,CCNE2,LMO7,NCKAP5,PAX6,SORBS1,SOD2,COL18A1,IL27RA,EXT2,SAP130,ZNF687,REEP1,EPB41L4B,ECE1,NFKB2,EBAG9,SEPHS1,SOAT1,PTPRU,GLO1,CD40,TMTC2,ARHGAP35,SECTM1,TLE1,RCAN2,SPTBN5,ABCA1,KDELC2,GLIS3,FBLIM1,ENO2,ARHGEF11,TSPAN15,SHPRH,SERPINB9,COL4A5,INTS8,SBF1,NTAN1,XPR1,ITGA2B,HDAC9,SYDE2,TMEM63A,KIF5B,TOP2A,CARD8,TAF1B,ADRBK1,LLGL2,BMP7,RRBP1,H2AFY,ARVCF,KANK2,SLC35A1,RPGR,MYO5A,RBMS2,PGM1,PHF20L1,DCAF6,SYBU,RC3H2,FAM73B,SWAP70,TRIM69,RND3,FIBCD1,CSGALNACT1,ARRB1,UACA,ZMIZ1,PLOD3,RAB3IL1,ABCG1,DOC2A,ACACB,TRIM24,ADD1,IL15RA,AASS,DNAJC3,MMADHC,CACNA2D2,SMARCAL1,DHX8,FAM102B,NRG2,CNTROB,CA8,BARD1,PHF1,ZYX,TGFBR3,RGS12,PQLC2,KIAA1107,CYP2S1,KLF3,FUT1,TUBG1,SEMA3G,TINAGL1,PIK3CD,ACOX2,ODF2L,ERAP2,NWD1,SMARCA2,SPEF2,LOXL2,F12,MYOM1,CYP4F3,COL12A1,SLC44A3,WDR11,DNM1L,ANKRD6,LIMK1,MYLK,MAP3K11,AGFG2,SERPINB6,MRPS28,RELL1,PDPR,E2F8,GAB1,FAM169A,TMTC3,CYP2J2,STRN4,MERTK,LMNA,ELF3,DNPEP,WDFY1,FAM189A1,CD22,NEK2,NCAM1,EPHX1,NAGPA,SLC37A1,KIF20A,TP53INP2,SPTLC2,DHX32,PTPRF,NAAA,NCOA3,MTFMT,HTT,SETD3,ITPR1,DYSF,ARPC2,NDE1,TRPC3,XDH,ARHGAP11A,GRHL2,GALNT12,ACTR8,PKP2,IL13RA1,NUF2,PRSS22,APC2,TNFSF9,ZNF385B,UHRF1BP1L,SCNN1A,SP100,DACT1,RTKN2,SCN3A,RNF169,ENPP4,FZD4,SYNE2,NUSAP1,CDCA2,RAB38,PEX5,SLC9A6,WWTR1,SIPA1L1,INPP4B,PLEKHG1,RGS14,ARNT,FARP1,TNRC6C,TAOK2,ANO9,PKN1,KCNC4,NEO1,DTX3L,CAPN2,ANK1,ADD3,SLC27A6,ARSG,CTSC,ANKS1B,KCNK5,ADAM15,ZNF230,WWP1,AK3,SGCB,ITM2C,TPCN1,TMX1,HCN3,AMOTL2,FMN1,CTNNAL1,RAPGEF2,ELOVL3,GRIN1,PLEKHA7,SNTB1,ABLIM2,GALNT3,KIAA0141,ACVRL1,NR1D2,CCDC6,ATXN7L3,ZFP30,ARFGAP3,FHL1,CENPE,NUP37,FOXA1,DCBLD1,TRIM2,AGRN,FAM199X,CUL4B,EPHA4,FHDC1,MCCC1,NDC80,CDIPT,HDAC6,PIGL,SHC3,MKRN3,DDHD2,DUSP10,RGS5,TLN2,ANO4,MYBL1,S100A13,NEB,ZNF462,ESYT1,ANLN,IDH1,LHFPL2,CLCN2,VCP,OPTN,PLCH1,MFAP3L,TBC1D17,MSL1,WIPI1,MAP2,DOLPP1,RAB11FIP1,PRKCDBP,PIK3C2B,EPB41L4A,POMT1,GLCCI1,PRKAA2,CHCHD7,ASAH1,CNTNAP2,DOCK11,IL18R1,PGAP1,SSX2IP,BMP2,RB1,VASP,DAZAP1,KIAA0895,IGF1R,TMEM8A,PLCB2,PSMA5,ABCC1,CHSY3,WDR72,EIF2AK1,MOSPD3,COQ10A,H1F0,CSF1,ITGA7,LTBP2,ATP1B3,KCNAB3,NF2,UPF3B,FOXM1,DGKA,ZNF28,ERBB2,SLC7A2,FAM198B,LPIN3,CYP26A1,SDF4,C1orf116,PER2,RAD23A,SRPX,EFR3A,PLCG2,SRR,MINPP1,SCN2A,EGLN3,DVL2,SIRT1,TMTC1,MBP,FIGNL1,MYL12A,DUOX1,DNAJC10,RTN4RL1,PSMD3,ADAMTS14,ANXA9,AIFM3,NDST3,CMTM4,MAN2B2,GOLIM4,PACSIN2,CD63,MACC1,RUSC2,GABRG2,NKRF,JAG2,CHAC2,CRABP2,PPP2R3A,SLC9A2,CEP97,MAGEE1,BUB1,KLF9,CAMK2G,TLE6,DLGAP1,HMMR,IFITM3,AMFR,PPARA,TRIM35,AKAP3,BCAR1,BSDC1,MAPK8IP1,PRDX4,FUCA1,BANK1,FAT4,SERPINA1,TWSG1,ZNF214,CDCA7L,ACADM,TBC1D4,NDFIP1,DIS3L,SUN1,GAA,PPP4R4,TTC39B,ATP8A1,PPFIBP2,GATA3,PLXNA1,CCNB1,SLC20A1,ELMOD2,CENPN,CHST2,CTGF,ZFP36,PRICKLE3,IQCE,RGS3,IL31RA,STEAP2,AOX1,ATRNL1,IQCD,MTMR11,TFG,SMYD5,SNTB2,PBK,HSPA12A,MGAM,TNS1,AURKB,GALNT7,CCNF,SAV1,TP53I3,SPNS3,ULK2,SFXN1,RBM47,AREG,PLK2,GNPTAB,NKD1,DHTKD1,UNC5B,TANC2,RTN3,DDX58,CDK17,INPPL1,FRMD4A,DGKQ,SLC25A27,KIF23,NOTCH2,SLC1A3,KIAA1161,MECOM,ITGA3,PIK3AP1,SLC16A6,BDH1,RUNDC3B,SORL1,CD70,PIKFYVE,TSPAN33,TMED2,EEF1D,IGSF3,DNAI1,EPB41L5,B3GNT7,KIAA1841,MFI2,TBC1D8B,PTPRH,PIP4K2C,FAM133B,PKM,KDM3A,GLT8D2,FRMD4B,DGKH,GABRD,PRKAG2,SLC4A3,FGD6,MAP3K5,PKD1L2,IRF1,PLA2G4A,PLEKHG3,SLC2A4,ARMCX3,TRIP10,NLRX1,SUZ12,IQGAP1,RPS6KA1,IRX4,RNF182,CD274,EGR3,AIFM2,GNB2,SLC25A35,CYHR1,APLP2,DOK4,TNPO2,CNNM4,PHKA2,LGMN,NR2C1,GPX4,TBC1D10B,MYO5B,SEC23A,SLC5A11,CDKN2AIP,CAPN6,TMEM43,TEP1,COX11,PRKCQ,C15orf39,H2AFV,SP4,NIN,EPHA10,FYN,PPP2R5A,SLC27A1,NRG1,ZC3H12B,MLKL,ATMIN,DENND5B,MRPS9,ARHGEF3,ANKRD13D,SLC16A14,CDCA3,CCNJL,CYB561,APOBEC3H,PNPLA5,TEAD3,TMCC3,FAM111A,C16orf59,PHF7,PTEN,MGAT1,CENPJ,SGK3,TRIM62,OSGIN1,NCOA2,SMC4,RASGRF1,ARAP2,ERMAP,MPP1,DENND1B,FURIN,PARP4,LRRC1,MAMDC4,RCBTB2,PRDX3,CCDC69,CSTF2,GRIN2D,SLC25A38,NCAPG2,JARID2,ESYT2,EXPH5,EMX1,LTBP1,CPT2,CAMKK1,UBE2Z,TAF6L,DNER,KREMEN1,TMC1,DENND2D,SH3KBP1,PTCHD4,CHPF,NKAIN3,ARHGEF10L,ZCCHC12,DPYSL2,PHTF1,CAPG,DLG1,ANKRD12,SUN3,MYH14,ARNT2,SLC39A10,TECR,PTPRE,RASGRP1,ATL1,TDP1,TRIM8,RNF165,ROR1,PTGFRN,STK17B,TCN2,ZNF114,ARHGEF19,NEIL1,FASTKD1,IARS2,TRIM45,CCDC74B,ADIPOR1,APBA2,PSMC1,MIIP,PPP2R5D,CPPED1,STARD3NL,LRRFIP2,PEX6,ATP6V1E2,PHLPP1,ZNF432,AIM1L,CA2,KCNN4,FNIP1,KNTC1,NCEH1,PARD3B,GYLTL1B,AMDHD1,EGFR,MUM1L1,GLCE,GNAS,XKRX,FECH,TSC1,ONECUT1,SLC6A6,CGREF1,RHOBTB2,ALPK3,EGFL7,KIF12,FBXW5,PROM2,GAS2L1,ZSWIM5,FAM92A1,SLC2A8,MORC4,TDRKH,MICALL2,ARHGEF16,LRRC45,SS18,SETDB2,KHNYN,FRYL,SMO,STEAP3,RPN2,SCYL3,IGSF8,ERBB2IP,DOCK5,BFSP1,BHLHB9,OVOL1,CANT1,VSIG10,PLXND1,CYP2U1,AKNA,SGOL1,REEP4,LIFR,CDS2,JKAMP,FRMD6,ARMC7,LRP4,FAM134A,ZNF212,SNX13,ADORA1,GALNS,KIAA0319,BRD7,TRIM3,HSPA13,IQGAP3,SUN2,ADAM17,RAB3B,ASPM,PHLDB3,NR4A1,LRRC66,OGDHL,SPAG1,MAP1B,KLHL2,C2orf70,PRCP,DHRS2,OTUB2,GLB1,SOX8,ATP6V1C1,L1CAM,ZNF596,SNPH |
| 1.722e-02 | -4.06 | primary active transmembrane transporter activity | molecular function | GO:0015399 | 115 | 26 | 16491 | 2452 |
SEC61G,ATP8A1,ATP2C2,ABCG4,ABCG2,TAP1,ATP6V1E2,SLC11A2,ATP1B1,ATP13A2,ABCD4,ATP6V0B,TAPBP,ATP1A1,ATP7B,ATP13A3,ABCB1,PCYOX1,ABCA2,ABCD1,ATP1B3,ATP6V1C1,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 1.722e-02 | -4.06 | P-P-bond-hydrolysis-driven transmembrane transporter activity | molecular function | GO:0015405 | 115 | 26 | 16491 | 2452 |
SEC61G,ATP8A1,ATP2C2,ABCG4,ABCG2,TAP1,ATP6V1E2,SLC11A2,ATP1B1,ATP13A2,ABCD4,ATP6V0B,TAPBP,ATP1A1,ATP7B,ATP13A3,ABCB1,PCYOX1,ABCA2,ABCD1,ATP1B3,ATP6V1C1,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 1.726e-02 | -4.06 | BROWNE_HCMV_INFECTION_14HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_UP | 151 | 32 | 17758 | 2588 |
CCNE2,GCLM,HLA-F,TSC22D3,EPHA4,ETV5,TAF6L,HOXB2,PDIA4,CDS1,M6PR,ATP6V0B,FICD,ZNF230,USP1,TIAM1,HES1,ING1,CASK,TAF5,PAPD7,GCLC,SYNE2,CALCRL,BCL7B,CCNF,FOS,VCP,SPAG1,GLA,FZD5,ATP6V1C1 |
| 1.726e-02 | -4.06 | GAGCTGG,MIR-337 | MSigDB lists | GAGCTGG,MIR-337 | 151 | 32 | 17758 | 2588 |
IER5L,SORT1,PACSIN2,ARAP3,THRA,DNAJB2,BCL2L1,GRK6,EFNB1,TEAD3,RAB15,MAP3K9,TWIST1,CAMK2G,MAP3K3,SEPT6,PARD3B,RNF165,WHSC1,TRIM35,FAM133B,FOS,TYSND1,VCP,USP6,KLF12,H1F0,OVOL1,KLF11,B4GALT3,GLCCI1,ACOT7 |
| 1.726e-02 | -4.06 | PSME1 (proteasome activator subunit 1) | protein interactions | 5720 | 68 | 18 | 16036 | 2547 |
PSRC1,PSMB4,TUBB4B,PSME2,PSME1,ATP1B1,PSMA4,SMN1,KIF5B,CYP1A1,PSMD1,OXCT1,PRDX3,PSMC2,PAK2,TUBG1,RNF26,PSMC1 |
| 1.731e-02 | -4.06 | Cell adhesion molecules (CAMs) | KEGG pathways | hsa04514 | 142 | 32 | 6908 | 1076 |
CD99,MPZL1,HLA-F,HLA-E,ITGA6,SDC4,SELL,F11R,CNTNAP2,CD274,SDC1,HLA-A,ICAM1,NEO1,CDH1,ITGB8,CD22,CDH3,CLDN4,HLA-C,NCAM1,CD40,ALCAM,CNTNAP1,PTPRF,HLA-B,CD8A,PVRL2,ITGAV,ICOSLG,L1CAM,OCLN |
| 1.731e-02 | -4.06 | Cell adhesion molecules (CAMs) | KEGG pathways | ko04514 | 142 | 32 | 6908 | 1076 |
CD99,MPZL1,HLA-F,HLA-E,ITGA6,SDC4,SELL,F11R,CNTNAP2,CD274,SDC1,HLA-A,ICAM1,NEO1,CDH1,ITGB8,CD22,CDH3,CLDN4,HLA-C,NCAM1,CD40,ALCAM,CNTNAP1,PTPRF,HLA-B,CD8A,PVRL2,ITGAV,ICOSLG,L1CAM,OCLN |
| 1.731e-02 | -4.06 | JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP | MSigDB lists | JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP | 48 | 13 | 17758 | 2588 |
PPP2R5A,TCEB2,DLGAP5,AKT1,GCAT,PAK2,PPP1CB,IL17RA,SPCS3,GNB2,NAGA,IL18R1,MPV17L2 |
| 1.731e-02 | -4.06 | MARCHINI_TRABECTEDIN_RESISTANCE_DN | MSigDB lists | MARCHINI_TRABECTEDIN_RESISTANCE_DN | 48 | 13 | 17758 | 2588 |
CALR,MARCH8,HLA-B,BCAM,HSP90B1,RND3,RUSC2,ACTA2,NOTCH3,PKN1,CITED2,LOXL1,SIRPA |
| 1.731e-02 | -4.06 | STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_PATHWAY | MSigDB lists | STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_PATHWAY | 48 | 13 | 17758 | 2588 |
TAOK2,SH2D3C,CCM2,KIAA1804,MAP3K11,MAP3K9,DUSP10,MDFIC,MAP3K5,PKN1,MAP3K6,MAPK8IP1,MDFI |
| 1.737e-02 | -4.05 | transition metal ion homeostasis | biological process | GO:0055076 | 131 | 29 | 16441 | 2455 |
SOD1,MFI2,EPAS1,ABCG2,XIAP,ACO1,ATP6V1E2,TTC7A,EIF2AK1,SLC11A2,FTH1,NUBP1,SFXN5,STEAP1,NEO1,FECH,SFXN1,ATP6V0B,APLP2,HTT,ATP7B,SLC46A1,STEAP2,STEAP3,ATP6V1C1,SLC39A10,NDFIP1,SLC31A2,CYBRD1 |
| 1.740e-02 | -4.05 | mixed_adenosquamous_carcinoma | COSMIC cancer mutations | mixed_adenosquamous_carcinoma | 112 | 25 | 17775 | 2585 |
DCAF6,AKT1,RET,TP53,RHPN2,ERBB2,IDH1,FLT3,EGFR,GNAS,KIF5B,HLA-B,RB1,CTNNB1,CDH1,ANKS1B,PTEN,FGFR2,CCDC6,PIK3CA,PLEKHG1,SMO,TFG,JAK3,TLL2 |
| 1.742e-02 | -4.05 | sulfur compound biosynthetic process | biological process | GO:0044272 | 204 | 42 | 16441 | 2455 |
SLC35D2,ACACB,GCLM,PAPSS2,XYLT1,ELOVL7,MGST2,B4GALT4,DSE,GSTP1,EXT2,CHST2,CHPF,XYLT2,PAPSS1,GOT1,AHCY,APIP,ACSL4,TECR,CTH,CHSY3,B3GALT6,OPLAH,B3GNT7,B3GNT2,GCLC,ELOVL3,PXYLP1,PDHX,GLCE,HS6ST1,SLC35B3,CSGALNACT1,B4GAT1,HS3ST3B1,B4GALT3,ST3GAL1,NDST3,ACOT7,HS6ST3,DLAT |
| 1.752e-02 | -4.04 | PTPRF (protein tyrosine phosphatase, receptor type, F) | protein interactions | 5792 | 49 | 14 | 16036 | 2547 |
IRS2,PTPRF,UFD1L,FYN,INSR,ADRBK1,CTNNB1,CDH1,RET,RYK,BCAR1,PPP2R5D,EGFR,SEPHS1 |
| 1.755e-02 | -4.04 | regulation of blood vessel endothelial cell migration | biological process | GO:0043535 | 47 | 13 | 16441 | 2455 |
PTGS2,PLCG1,PDCD10,AKT1,ACVRL1,PRCP,RGCC,EFNA1,VASH1,PDGFB,HSPB1,SRPX2,HDAC9 |
| 1.755e-02 | -4.04 | mammary gland morphogenesis | biological process | GO:0060443 | 47 | 13 | 16441 | 2455 |
NCOA3,AREG,FGFR2,CSF1,STAT6,ERBB2,TFAP2C,SCRIB,NTN1,ETV4,SLC12A2,CAPN1,ELF3 |
| 1.755e-02 | -4.04 | regulation of dendritic spine development | biological process | GO:0060998 | 47 | 13 | 16441 | 2455 |
GRN,FOXO6,PTEN,BHLHB9,PLK2,SIPA1L1,EPHA4,NRG1,EFNA1,ARF6,ITPKA,CDK5R1,NGEF |
| 1.755e-02 | -4.04 | negative regulation of DNA binding | biological process | GO:0043392 | 47 | 13 | 16441 | 2455 |
ZNF462,CTNNBIP1,TFAP4,SP100,NFKBIA,HABP4,NEK2,PPARA,E2F1,SMO,NFIB,PER2,MDFI |
| 1.755e-02 | -4.04 | regulation of actin filament depolymerization | biological process | GO:0030834 | 47 | 13 | 16441 | 2455 |
SWAP70,PLEKHH2,ADD1,DMTN,DSTN,EPS8,CAPG,TRIOBP,TMOD2,SPTBN5,SHROOM2,F2RL1,SPTB |
| 1.755e-02 | -4.04 | TARS (threonyl-tRNA synthetase) | protein interactions | 6897 | 73 | 19 | 16036 | 2547 |
GFPT1,UGP2,FAM129B,NDRG1,CUL1,VPS26A,DCP2,EGFR,CORO1B,ELF3,BCAR3,HLA-B,ZYX,PRKAG2,CORO1C,FAM114A1,AURKA,HSPB1,DVL2 |
| 1.761e-02 | -4.04 | BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase) | protein interactions | 8945 | 335 | 68 | 16036 | 2547 |
CASP3,DLGAP5,SUZ12,PTTG1,TP53,CUL1,CCNB1,PRKACA,CHPF,PER2,CCND1,WEE1,CTNNB1,ELMO2,DACT1,DLG1,PLK4,CRY2,CTTN,NFKB2,TIAM1,CDC20,NFE2L1,RGAG1,MRPS35,MRPS18A,ERBB2IP,CDK1,VCP,TRIM9,WWTR1,ZNF704,HSPB1,RAP1GAP,PRKAR1A,FGD1,MRPL44,ZNF395,NFKBIE,TSPAN15,NUAK1,PHLPP1,TRIB2,SSX2IP,CKAP5,ELF3,TFAP4,IRAK1,FNIP1,KANK2,FAM219A,ALDH3A2,ACBD5,SUN2,UFD1L,ALDH2,TACC1,RAPGEF2,AMER1,BORA,RASA1,BCL10,BTG1,NFKBIA,UBE2D2,E2F1,AURKA,TBC1D4 |
| 1.765e-02 | -4.04 | GLYCOPROTEIN_METABOLIC_PROCESS | MSigDB lists | GLYCOPROTEIN_METABOLIC_PROCESS | 90 | 21 | 17758 | 2588 |
TNIP1,COG2,MAN1A2,BACE1,MGAT4B,ERP44,GALNT7,POMGNT1,TSPAN7,B3GALNT1,FUT2,NECAB3,DOLPP1,MGAT4A,FUT8,FUT1,STT3B,ALG2,POMT1,GCNT1,ABCG1 |
| 1.765e-02 | -4.04 | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | 90 | 21 | 17758 | 2588 |
TTC39B,PLSCR1,SH3BGRL,STAT4,ITGA6,P2RX7,PLA2G16,NUCB2,ATP10D,ENDOD1,IGF1R,ITGB8,SNX18,LRIG1,CAPG,AHCY,SELK,ITGAV,TIAM1,GPX4,RRAGD |
| 1.774e-02 | -4.03 | GCAAAAA,MIR-129 | MSigDB lists | GCAAAAA,MIR-129 | 180 | 37 | 17758 | 2588 |
PAX6,PPP1R12A,FAM160B1,ITGA6,SLC25A27,NRG2,ETS1,VPS26A,SH3KBP1,LMNA,IRF2BPL,ZFX,SP100,EFR3A,ANKS1B,FAM13B,BCL6,DUSP10,DAB2IP,ACSL4,SUN2,OXR1,PIK3R1,RNF165,VCP,SP4,USP6,PLCG1,PAPD5,SFMBT1,PITPNA,CTNND1,NR4A2,ARNT,CBX7,NR3C2,NR2C2 |
| 1.774e-02 | -4.03 | GSE3982_BCELL_VS_TH1_UP | MSigDB lists | GSE3982_BCELL_VS_TH1_UP | 180 | 37 | 17758 | 2588 |
ST13,REPS2,IL27RA,TRMT2B,PHF1,SLC9A2,ABCD4,DOPEY2,CA2,CTGF,RALGPS2,GNB5,DACT1,CD22,OPN3,CNPY3,SYK,FARP2,VPS11,ALDH2,TCFL5,CRIP2,SYBU,LOXL2,CD83,MAGED2,IRS2,ALDH5A1,FA2H,SLC25A4,STAT6,SPINT2,S100A5,CSGALNACT1,TMEM8B,LTA4H,ARHGEF4 |
| 1.774e-02 | -4.03 | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_UP | 180 | 37 | 17758 | 2588 |
MRC2,ENO2,TSPAN15,ITGA6,GATA3,DPP8,PHLDA1,HOXB2,ANO1,NOV,FRY,SORL1,ATRNL1,PLEKHF1,PIM1,DLG3,DLX4,CYP1B1,RASGRF1,DENND1B,STAT4,BCL9,DCHS1,TMEM144,PLS1,PRKCQ,DUSP4,ULK2,EDNRA,FRMD4B,HLF,SEMA4D,CGREF1,AMMECR1,INPP4B,RUSC1,RRAGD |
| 1.774e-02 | -4.03 | GSE3982_DC_VS_BCELL_DN | MSigDB lists | GSE3982_DC_VS_BCELL_DN | 180 | 37 | 17758 | 2588 |
KLF2,GOLIM4,CNOT8,BIK,TESK2,GTF3A,TRIB2,KCNC4,FAM46C,HOXB2,PHF1,HLA-A,PARM1,WEE1,KIF13B,UBE2J1,SORL1,EEF1D,DUSP1,PRODH,CENPA,FOXJ2,SYBU,TCF7,MEST,GALNT3,JAK1,ACAD10,C19orf66,DOLPP1,CSGALNACT1,FAM117A,IRF7,PIK3C2B,TMEM8B,RGS14,CTBP1 |
| 1.778e-02 | -4.03 | positive regulation of osteoblast differentiation | biological process | GO:0045669 | 57 | 15 | 16441 | 2455 |
CTNNBIP1,GNAS,BMP2,CTHRC1,RUNX2,ACVR1,CTNNB1,WNT10B,CYR61,NPNT,FAM20C,IL6ST,BMP7,SUCO,ILK |
| 1.778e-02 | -4.03 | phospholipid transport | biological process | GO:0015914 | 57 | 15 | 16441 | 2455 |
ATP9A,MFSD2A,KCNN4,ATP8A1,TMEM30A,ATP8B1,P2RX7,PITPNA,NPC2,ATP8B3,PCTP,CPTP,ATP10D,ABCA1,ABCG1 |
| 1.778e-02 | -4.03 | chondroitin sulfate metabolic process | biological process | GO:0030204 | 57 | 15 | 16441 | 2455 |
B3GALT6,CHSY3,HSPG2,AGRN,XYLT2,IMPAD1,GPC3,SDC4,XYLT1,HEXB,CSGALNACT1,DSE,ARSB,SDC1,CHPF |
| 1.778e-02 | -4.03 | gastrulation | biological process | GO:0007369 | 159 | 34 | 16441 | 2455 |
ACVR1,TNRC6C,NF2,TP53,NCKAP1,PRKACA,EXT2,DUSP5,ITGA3,CTNNB1,DACT1,BMP7,MEGF8,ELF5,COL6A1,WNT3A,DVL2,DUSP1,EPB41L5,ARFRP1,COL7A1,DUSP4,NPHP3,COL12A1,MMP15,ETS2,FGFR2,HTT,TWSG1,PLPP3,ITGA7,NR4A3,ITGAV,PRKAR1A |
| 1.778e-02 | -4.03 | - | gene3d domains | 1.10.150.50 | 104 | 25 | 9988 | 1574 |
ARAP2,ARAP3,INPPL1,EPHA4,PPFIBP2,EPHA1,SAMD9,ETS1,ELF3,SCML1,DGKH,TP73,EPHA10,ANKS6,ETS2,STIM1,ANKS1B,DDHD2,ELF5,ARAP1,SFMBT1,SAMD8,EPHB4,ETV7,PHC1 |
| 1.781e-02 | -4.03 | angiosarcoma | COSMIC cancer mutations | angiosarcoma | 2284 | 366 | 17775 | 2585 |
FAM171B,ADD1,LGR4,SSH1,AASS,SLC25A13,ATP8A1,TSC22D3,DNAJC3,HEXB,PPFIBP2,TRAPPC8,SYTL4,PLXNA1,SEPT4,CA8,SLC9A7,CYP1A1,DNAH6,AOX1,PIK3CA,ATRNL1,SNX16,TIAM1,MGAT5,NBPF3,TNS1,PPP1R14C,CCNF,MYOM1,POR,COL12A1,AHRR,KDSR,PLCG1,DNM1L,ATP7B,MYLK,PRDM5,FAM110C,TANC2,TRAF5,GAB1,KLF2,FRMD4A,ALDH6A1,TBC1D1,KIF23,SLC36A4,SLC1A3,NOTCH2,APBA1,FAM21C,PDXDC1,MECOM,RALGPS2,FRY,FAM189A1,BDH1,PRKG1,MAP3K9,SORL1,CADPS2,STT3B,CACNA1D,KCTD3,RIMS2,MCCC2,TMED2,PAQR7,EPB41L5,PIGC,STAT4,GNA11,SLCO4A1,AP1AR,PRKAG2,PLEKHH2,HTT,FAAH,PCDH19,IFIH1,RPS6KA3,XDH,ADAMTS16,WDR63,PLA2G4A,TCTN2,FAM131C,IQGAP1,APOO,PKP2,RNF182,GRK6,CD274,FAM91A1,APC2,TNFSF9,KIAA1147,ZNF385B,UHRF1BP1L,RCN1,MUC16,RNF220,ACAP2,CDH1,RTKN2,MYO5B,SNX8,CDKN2AIP,ERMP1,COG2,AGPS,PTPN9,SYNE2,CLSTN1,UTRN,TEP1,TANC1,ITPR3,ALCAM,TRIQK,ATP10D,NIN,CMTM7,CCNB3,CDK19,ZNF704,PLEKHG1,HS3ST3B1,NR3C2,COBL,MAMDC2,DENND5B,FARP1,TAOK2,FAM189A2,PARP14,CCM2,EPS8,DNAH3,SRPX2,HOXB2,PDCD10,TMEM87B,ITGB8,ANKS1B,ARSG,PTEN,TUBGCP6,FUT8,ATP8B1,FAM102A,TTPA,TRIM62,NCOA2,PCCB,PDGFC,ARHGEF28,CTNNAL1,TCFL5,MRS2,PIK3R1,PLEKHA7,DIAPH2,C2orf69,RAB3IP,AIF1L,SNTB1,ABLIM2,GALNT3,RGS9,PROM1,LDLRAP1,SLC35B3,PPM1H,GRIN2D,ITGAV,CD81,ARSB,USF2,ESPL1,PHC1,JARID2,RGMA,LTBP1,ARFGEF1,TEX2,NENF,MPP5,ITPR2,NUP62CL,DNER,CACNB4,KREMEN1,TMC1,NKAIN3,SIPA1L2,HSF2,CTNNB1,SHC3,PAPSS1,ANKFN1,PHTF1,SLC44A1,POF1B,TRPC1,RGS5,ARNT2,ANO4,MYRIP,TRAM1,ZNF462,TDP1,MARK1,ASXL1,RNF165,CR2,IDH1,CLCN2,ADRBK2,DZIP1L,PI4K2B,KCNMB4,HPSE,MAP2,HOXA9,IARS2,EPB41L4A,APBA2,TC2N,CPPED1,HS6ST3,PPP1R12A,ZCCHC24,UBASH3B,ABCG2,CALM3,CNTNAP2,PHLPP1,DOCK11,RSAD1,PGAP1,MYO5C,TNS3,DAZAP1,IGF1R,FAM20C,FRAS1,PRKCI,MDFIC,LIMCH1,KNTC1,PIM1,ZRANB1,ALDH3A2,CHSY3,WDR72,USP31,CORO2A,MGAT4B,KBTBD8,PDE5A,EIF2AK1,KIAA1109,SCRIB,HEATR5A,MFSD7,EGFR,NMT2,RHPN1,TSC1,ONECUT1,PHLPP2,CGREF1,PITPNA,PLD1,ZDBF2,USP43,GAS2L1,LMO7,NCKAP5,XYLT1,TP53,PDIA5,P2RX7,RHPN2,PATL2,PER2,CDK14,SLC25A48,CDH3,DIXDC1,NOTCH3,FAR1,UPF3A,EBAG9,CPD,TMTC1,CLCN3,AKT1,PTPRU,SLC39A8,TMTC2,DUSP4,DOCK5,FANCE,PDHX,DNAJC10,PTPRJ,C19orf66,ABHD12,STAT6,TLE1,EFNA5,SPTBN5,RCAN2,PLXND1,CYP2U1,LTA4H,COL9A3,PACSIN2,GOLIM4,CDH22,ARHGEF11,SCD5,GNAL,MCTP2,LRP4,ERCC6L,MIER3,NOTUM,FZD6,SLC9A2,PPP2R3A,CEP97,MLPH,MAGEE1,BMP7,TOX2,KIAA0319,IL17RA,H2AFY,BUB1,IQGAP3,MYO5A,HMMR,DLGAP1,FBLN5,GCLC,DEPDC4,RC3H2,MAML2,FNDC3A,POLD3,MAP1B,ARHGAP24,BANK1,RAP2C,CLIP4,UACA,PPP2R3C,GRAMD1C,TBC1D4,AHR,L1CAM |
| 1.781e-02 | -4.03 | soft_tissue-blood_vessel-angiosarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-angiosarcoma | 2284 | 366 | 17775 | 2585 |
FAM171B,ADD1,LGR4,SSH1,AASS,SLC25A13,ATP8A1,TSC22D3,DNAJC3,HEXB,PPFIBP2,TRAPPC8,SYTL4,PLXNA1,SEPT4,CA8,SLC9A7,CYP1A1,DNAH6,AOX1,PIK3CA,ATRNL1,SNX16,TIAM1,MGAT5,NBPF3,TNS1,PPP1R14C,CCNF,MYOM1,POR,COL12A1,AHRR,KDSR,PLCG1,DNM1L,ATP7B,MYLK,PRDM5,FAM110C,TANC2,TRAF5,GAB1,KLF2,FRMD4A,ALDH6A1,TBC1D1,KIF23,SLC36A4,SLC1A3,NOTCH2,APBA1,FAM21C,PDXDC1,MECOM,RALGPS2,FRY,FAM189A1,BDH1,PRKG1,MAP3K9,SORL1,CADPS2,STT3B,CACNA1D,KCTD3,RIMS2,MCCC2,TMED2,PAQR7,EPB41L5,PIGC,STAT4,GNA11,SLCO4A1,AP1AR,PRKAG2,PLEKHH2,HTT,FAAH,PCDH19,IFIH1,RPS6KA3,XDH,ADAMTS16,WDR63,PLA2G4A,TCTN2,FAM131C,IQGAP1,APOO,PKP2,RNF182,GRK6,CD274,FAM91A1,APC2,TNFSF9,KIAA1147,ZNF385B,UHRF1BP1L,RCN1,MUC16,RNF220,ACAP2,CDH1,RTKN2,MYO5B,SNX8,CDKN2AIP,ERMP1,COG2,AGPS,PTPN9,SYNE2,CLSTN1,UTRN,TEP1,TANC1,ITPR3,ALCAM,TRIQK,ATP10D,NIN,CMTM7,CCNB3,CDK19,ZNF704,PLEKHG1,HS3ST3B1,NR3C2,COBL,MAMDC2,DENND5B,FARP1,TAOK2,FAM189A2,PARP14,CCM2,EPS8,DNAH3,SRPX2,HOXB2,PDCD10,TMEM87B,ITGB8,ANKS1B,ARSG,PTEN,TUBGCP6,FUT8,ATP8B1,FAM102A,TTPA,TRIM62,NCOA2,PCCB,PDGFC,ARHGEF28,CTNNAL1,TCFL5,MRS2,PIK3R1,PLEKHA7,DIAPH2,C2orf69,RAB3IP,AIF1L,SNTB1,ABLIM2,GALNT3,RGS9,PROM1,LDLRAP1,SLC35B3,PPM1H,GRIN2D,ITGAV,CD81,ARSB,USF2,ESPL1,PHC1,JARID2,RGMA,LTBP1,ARFGEF1,TEX2,NENF,MPP5,ITPR2,NUP62CL,DNER,CACNB4,KREMEN1,TMC1,NKAIN3,SIPA1L2,HSF2,CTNNB1,SHC3,PAPSS1,ANKFN1,PHTF1,SLC44A1,POF1B,TRPC1,RGS5,ARNT2,ANO4,MYRIP,TRAM1,ZNF462,TDP1,MARK1,ASXL1,RNF165,CR2,IDH1,CLCN2,ADRBK2,DZIP1L,PI4K2B,KCNMB4,HPSE,MAP2,HOXA9,IARS2,EPB41L4A,APBA2,TC2N,CPPED1,HS6ST3,PPP1R12A,ZCCHC24,UBASH3B,ABCG2,CALM3,CNTNAP2,PHLPP1,DOCK11,RSAD1,PGAP1,MYO5C,TNS3,DAZAP1,IGF1R,FAM20C,FRAS1,PRKCI,MDFIC,LIMCH1,KNTC1,PIM1,ZRANB1,ALDH3A2,CHSY3,WDR72,USP31,CORO2A,MGAT4B,KBTBD8,PDE5A,EIF2AK1,KIAA1109,SCRIB,HEATR5A,MFSD7,EGFR,NMT2,RHPN1,TSC1,ONECUT1,PHLPP2,CGREF1,PITPNA,PLD1,ZDBF2,USP43,GAS2L1,LMO7,NCKAP5,XYLT1,TP53,PDIA5,P2RX7,RHPN2,PATL2,PER2,CDK14,SLC25A48,CDH3,DIXDC1,NOTCH3,FAR1,UPF3A,EBAG9,CPD,TMTC1,CLCN3,AKT1,PTPRU,SLC39A8,TMTC2,DUSP4,DOCK5,FANCE,PDHX,DNAJC10,PTPRJ,C19orf66,ABHD12,STAT6,TLE1,EFNA5,SPTBN5,RCAN2,PLXND1,CYP2U1,LTA4H,COL9A3,PACSIN2,GOLIM4,CDH22,ARHGEF11,SCD5,GNAL,MCTP2,LRP4,ERCC6L,MIER3,NOTUM,FZD6,SLC9A2,PPP2R3A,CEP97,MLPH,MAGEE1,BMP7,TOX2,KIAA0319,IL17RA,H2AFY,BUB1,IQGAP3,MYO5A,HMMR,DLGAP1,FBLN5,GCLC,DEPDC4,RC3H2,MAML2,FNDC3A,POLD3,MAP1B,ARHGAP24,BANK1,RAP2C,CLIP4,UACA,PPP2R3C,GRAMD1C,TBC1D4,AHR,L1CAM |
| 1.781e-02 | -4.03 | KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | 74 | 18 | 17758 | 2588 |
NFKBIE,AKT1,INPP5D,PIK3R1,CR2,RASGRP3,FOS,NFAT5,BCL10,RAC2,PIK3AP1,CD22,NFKBIA,PLCG2,PIK3CA,PIK3CD,CD81,SYK |
| 1.781e-02 | -4.03 | GLYCOPROTEIN_BIOSYNTHETIC_PROCESS | MSigDB lists | GLYCOPROTEIN_BIOSYNTHETIC_PROCESS | 74 | 18 | 17758 | 2588 |
TNIP1,COG2,MAN1A2,MGAT4B,GALNT7,POMGNT1,TSPAN7,B3GALNT1,FUT2,NECAB3,MGAT4A,DOLPP1,FUT8,FUT1,STT3B,ALG2,POMT1,GCNT1 |
| 1.781e-02 | -4.03 | CROMER_METASTASIS_UP | MSigDB lists | CROMER_METASTASIS_UP | 74 | 18 | 17758 | 2588 |
FADS2,GPR107,MICB,SH3BGRL,TSC22D3,TFAP2C,ARHGDIB,TMEM63A,SLC25A36,MAGED2,CNOT2,CD46,GNS,PLCG1,CTNNB1,PGRMC1,AGFG2,RPN2 |
| 1.783e-02 | -4.03 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | 112 | 25 | 17758 | 2588 |
KLF2,HAL,GATA3,SELL,HERC5,TCF7,IL13RA1,SLC1A3,FLT3,MYO5C,HLA-B,PROM1,INSR,ADD3,FAAH,RPL39,DACT1,MYLK,BCL6,SH3BP4,SORL1,IRF7,HLA-C,PTPRE,SGCB |
| 1.783e-02 | -4.03 | EEF1A2 (eukaryotic translation elongation factor 1 alpha 2) | protein interactions | 1917 | 83 | 21 | 16036 | 2547 |
LGR4,CUL4B,CUL1,IGSF8,PKM,DCP2,VCP,FAM177A1,RPL12,PSMD1,PTEN,PLK2,DDHD2,DCUN1D1,AURKA,ARRB1,TUBG1,AHCY,RNF26,CD81,EEF1D |
| 1.787e-02 | -4.02 | ROESSLER_LIVER_CANCER_METASTASIS_UP | MSigDB lists | ROESSLER_LIVER_CANCER_METASTASIS_UP | 101 | 23 | 17758 | 2588 |
HMMR,ENO2,GCLC,VAMP3,RGS20,COL4A5,TGOLN2,PLD2,YES1,MAP3K6,CDS1,PITX2,ALDH3B1,SPP1,NR1D2,LIMK1,FUT8,IRF2,GYS1,SERPINB6,HOXB13,CENPE,MDFI |
| 1.787e-02 | -4.02 | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | MSigDB lists | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | 101 | 23 | 17758 | 2588 |
PSME2,USP18,TAP1,LITAF,FLOT1,PSME1,IFIT3,RNF19B,IL18R1,LGALS3BP,ICAM1,FAS,TAPBP,IL6ST,AIM1,NFKBIA,STAT1,NFKBIZ,IRF7,IFIT1,SNX10,IRF1,XDH |
| 1.787e-02 | -4.02 | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP | MSigDB lists | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP | 101 | 23 | 17758 | 2588 |
ACVR1,CENPA,KIF20A,CELSR2,PLSCR1,SLC39A8,SYBU,PRIM1,NKAIN3,NCOA3,RNF128,CTSC,MATN2,ALDH1A3,TRIM45,ABCA2,CKS1B,KIF22,HS3ST3B1,TMEM159,NCAM1,CCNB2,RRAGD |
| 1.789e-02 | -4.02 | apoptotic signaling pathway | biological process | GO:0097190 | 368 | 70 | 16441 | 2455 |
LAMP1,CASP3,XIAP,SOD2,TP53,P2RX7,CUL1,BCL2L1,ZNF385B,ARHGEF16,IER3,TP73,SIVA1,TNFRSF18,DAB2IP,SCN2A,TIAM1,CYP1B1,SIRT1,AKT1,CASP9,BNIP3L,CD40,CASP4,ABR,SGPP1,DNAJC10,DNM1L,NGFRAP1,ARHGAP4,UNC5B,FGD1,ZMAT1,SORT1,BMF,ARHGEF3,ARHGEF11,ARHGEF7,TRAF2,DAP,SGPL1,PDCD10,ADORA1,MCF2L,BAX,DAPK1,MSH2,TMBIM6,TNFRSF12A,CD70,SELK,ERBB3,MSH6,P2RX4,PRODH,ERO1A,PIK3R1,FAS,CASP7,KIAA0141,ITPR1,E2F1,UACA,ITGAV,MAP3K5,IFI6,ARHGEF9,MELK,NGEF,ARHGEF4 |
| 1.794e-02 | -4.02 | hydrolase activity, acting on acid anhydrides | molecular function | GO:0016817 | 810 | 142 | 16491 | 2452 |
ATP8A1,KLC2,TAP1,SMARCAL1,DHX8,PHOSPHO1,KIF2C,SEPT4,KIF26A,PICK1,ABCD4,RAB15,HELZ2,ENTPD4,DNAH6,ARL1,PSMC2,ATP13A3,ABCA2,DNM2,TUBG1,RAB20,KIF22,MYH14,DDX59,TUBA4A,ATL1,SMARCA2,KIFC2,ARHGDIB,KIF13A,ARFRP1,PIF1,RHEB,VCP,RAB2B,GINS4,ARF4,ENPP1,DNM1L,DOLPP1,ATP7B,PPP2R4,ARF6,RAP1GAP,PSMC1,RRAGD,DDX58,RECQL,PEX6,ABCG2,RAB23,ATP6V1E2,KIF23,RAB6A,MYO5C,RAC2,ATP5H,KIF13B,PCYOX1,MSH2,SRP54,DNAI1,ABCC1,KIF20A,KIF20B,ATP8B3,GNA11,DCP2,RHOB,DHX32,GNAS,NUDT16,RAB31,ATP1B3,KIF12,IFIH1,KIF3C,DYNLRB1,TUBB4B,RALBP1,ATP2C2,ABCG4,MRAS,NUDT12,GNB2,APPBP2,ATP6V0B,RALB,KIF14,ARL4D,RAB27B,MX1,ENPP4,MYO5B,FIGNL1,VPS4B,KIF1C,ATP1B1,RAD17,RAB38,ATP10D,ATP13A2,TAPBP,IDE,ATP1A1,ACYP1,CANT1,XRCC3,RAB29,ABCA1,SHPRH,ATP9A,GNAL,ERCC6L,ARL4C,DNAH3,IFT27,RND1,DIRAS3,KIF5B,TOP2A,GNB5,GTF2F2,KLC3,ATP8B1,ABCD1,ERCC2,MSH6,ATP2B1,MYO5A,RAB3B,RHOA,LONRF3,KIF11,DDX23,RND3,ABCB1,CENPE,ATP6V1C1,GEM,ABCG1 |
| 1.798e-02 | -4.02 | negative regulation of cell migration | biological process | GO:0030336 | 193 | 40 | 16441 | 2455 |
TCAF1,ARAP3,NF2,ADGRG1,PKP2,VASH1,CORO1B,NOV,SVBP,PDCD10,TIMP1,ADORA1,SP100,PTEN,ADAM15,DAB2IP,TACSTD2,CITED2,CYP1B1,PTPRU,ACVR1C,PTGER4,RGCC,ARHGDIB,EPHA1,ILK,DAG1,RHOB,ABR,DPYSL3,PTPRJ,ACVRL1,CORO1C,RAP2C,NRG1,EGFL7,ARHGAP4,SEMA3A,MIIP,DRD1 |
| 1.799e-02 | -4.02 | regulation of ossification | biological process | GO:0030278 | 176 | 37 | 16441 | 2455 |
CTHRC1,RUNX2,ACVR1,SOX9,LRP4,PHOSPHO1,P2RX7,OSR2,PRKACA,FAM101B,DHRS3,BMP2K,CTNNBIP1,BMP2,CTNNB1,CYR61,NPNT,FAM20C,IL6ST,BMP7,TFAP2A,SUCO,TWIST1,WNT10B,ANO6,PTGER4,ILK,GNAS,ENPP1,AREG,SEMA4D,TWSG1,FGFR2,CSF1,PIAS2,OSR1,TOB1 |
| 1.803e-02 | -4.02 | Non-integrin membrane-ECM interactions | REACTOME pathways | R-HSA-3000171 | 42 | 12 | 8202 | 1235 |
PDGFA,CASK,AGRN,HSPG2,ITGA6,SDC4,NTN4,ITGAV,SDC1,DDR1,PDGFB,DAG1 |
| 1.803e-02 | -4.02 | Elastic fibre formation | REACTOME pathways | R-HSA-1566948 | 42 | 12 | 8202 | 1235 |
BMP2,LTBP1,FBLN5,ITGB8,BMP7,FURIN,LTBP2,LOXL2,ITGAV,FBLN1,LOXL1,LTBP3 |
| 1.805e-02 | -4.01 | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN | MSigDB lists | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN | 186 | 38 | 17758 | 2588 |
NFKBIE,IL15RA,TRIP10,SEC61G,CD82,SDC4,UBE2Z,P2RX7,EGR3,PLXNA1,CHST2,ICAM1,IER3,BTG3,FJX1,RUNDC3B,CD70,NFKB2,HP1BP3,PPIF,MARK1,TNIP1,SLC37A1,UXT,RC3H2,NFE2L1,SERTAD3,EZR,ARFRP1,AURKB,BSDC1,NIN,KDM4D,NFKBIA,SLC2A6,RAP2C,HOOK1,EHD1 |
| 1.805e-02 | -4.01 | P53_DN.V1_DN | MSigDB lists | P53_DN.V1_DN | 186 | 38 | 17758 | 2588 |
PLA2G4A,RGS20,CTSZ,KBTBD11,HOXB2,TNFSF9,TSPAN7,NRP2,ZFYVE16,SPP1,CA2,CDH1,FDXR,MITF,BAX,AKR1B1,ACTA2,SGK1,IGFBP2,ARNT2,HSPA2,MYO5A,DDB2,FBLN5,NR4A1,STAT4,HSPA12A,RUNX3,CYFIP2,SOCS3,FAS,FRMD4B,IL1R1,GPRC5B,STAT6,NR4A3,L1CAM,CBX4 |
| 1.805e-02 | -4.01 | GSE27786_NKCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_NKCELL_VS_MONO_MAC_DN | 186 | 38 | 17758 | 2588 |
SORT1,HJURP,NDC80,ERCC6L,SSX2IP,KIAA1147,RAC2,SRPX,LMAN2L,NEK2,KNTC1,IQGAP3,CITED2,GFI1,PLCB2,TIAM1,SNED1,SMC4,LAMP2,MCTP1,FAM160A1,ASPM,LPGAT1,C3orf52,VAMP3,STRADB,EMP3,CCDC34,CDC25C,ZNF469,PDE11A,BCAR3,PELI2,ZFP30,DTX4,E2F8,CTDSP1,ARHGEF4 |
| 1.805e-02 | -4.01 | GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP | 186 | 38 | 17758 | 2588 |
PCOLCE,ETV5,ETNK1,FLOT1,NDRG2,NDUFA4,COX7A2,M6PR,GNS,DAPK2,SPP1,METTL7A,PAPSS1,DRAM1,DUSP10,MARCH2,ACSL4,WBP4,SPRY2,CERS2,SOCS5,CKS2,ENPP4,DCAF6,ERP44,BLVRA,TCN2,KLHL2,DCTN6,FECH,WIPI1,CORO1C,PLA2G15,RAB31,PPM1H,PLXND1,MAD2L1BP,ABCA1 |
| 1.805e-02 | -4.01 | modification-dependent macromolecule catabolic process | biological process | GO:0043632 | 464 | 86 | 16441 | 2455 |
FAF2,PSME2,CUL4B,PTTG1,FBXO2,CUL1,UBE2Z,PSME1,MVB12B,CCNB1,HDAC6,RAD23A,PSMD1,KIF14,PSMC2,PLK1,SIRT1,SEC61B,ERLEC1,FBXL16,ITCH,USP18,RNF11,CDC20,VPS4B,RNF165,AURKB,CCNF,CBL,RNF19B,CDK1,VCP,ZMPSTE24,TRIM9,DNAJC10,PSMD3,WFS1,WWTR1,AREL1,PSMC1,PINK1,HSP90B1,JKAMP,DNAJB2,CIT,PSMD7,PSMD10,ZNRF3,FBXO6,DNAJB9,WWP2,RNF128,FBXO7,NEK2,UBE2J1,PCYOX1,FBXL14,WWP1,USP38,USP1,STT3B,ZRANB1,MYLIP,PSMA5,UFD1L,PSMB4,USP31,AMFR,NUB1,UBE2A,FBXO8,FBXO9,TP53INP2,PSMA4,FBXO10,USP6,UBE2D2,AURKA,ARRB1,YOD1,NDFIP1,UBE2C,RNF146,USP16,FBXW5,USP43 |
| 1.806e-02 | -4.01 | HIBCH (3-hydroxyisobutyryl-CoA hydrolase) | protein interactions | 26275 | 31 | 10 | 16036 | 2547 |
IRF2BPL,SOD1,ALDH6A1,HNRNPH2,PRCP,DSTN,CAB39,ALDH7A1,ACADM,ECI1 |
| 1.806e-02 | -4.01 | CLOCK (clock circadian regulator) | protein interactions | 9575 | 31 | 10 | 16036 | 2547 |
TFAP4,SIRT1,NR1D2,BHLHE41,PPP1CB,CRY2,PPP1CA,PER3,PPP2R5D,PER2 |
| 1.806e-02 | -4.01 | NUP85 (nucleoporin 85kDa) | protein interactions | 79902 | 31 | 10 | 16036 | 2547 |
HDAC11,PIK3R1,TGOLN2,RABL6,CD274,FBXO6,NUP37,PNKD,PRKACA,EGFR |
| 1.806e-02 | -4.01 | MAGEA4 (MAGE family member A4) | protein interactions | 4103 | 31 | 10 | 16036 | 2547 |
AMOTL2,MDM1,DCAF6,TRIM69,IQGAP1,PIAS2,PSMD10,ARNT2,BEX2,HLA-A |
| 1.822e-02 | -4.01 | APC/C:Cdc20 mediated degradation of mitotic proteins | REACTOME pathways | R-HSA-176409 | 72 | 18 | 8202 | 1235 |
PSMB4,PSME2,PTTG1,CDC20,PSMD7,PSMD10,PSME1,CCNB1,CDK1,PSMA4,CCNA2,PSMD1,PSMD3,PSMC2,NEK2,UBE2C,PSMC1,PSMA5 |
| 1.823e-02 | -4.00 | cell division site | cellular component | GO:0032153 | 53 | 14 | 17570 | 2579 |
PLEKHG6,RHOA,NF2,SSH1,SEPT6,MYLK,TUBGCP6,PLK4,RACGAP1,PKN1,NDE1,ANLN,ARF6,RHOB |
| 1.823e-02 | -4.00 | cell division site part | cellular component | GO:0032155 | 53 | 14 | 17570 | 2579 |
PLEKHG6,RHOA,NF2,SSH1,SEPT6,MYLK,TUBGCP6,PLK4,RACGAP1,PKN1,NDE1,ANLN,ARF6,RHOB |
| 1.825e-02 | -4.00 | basolateral plasma membrane | cellular component | GO:0016323 | 208 | 42 | 17570 | 2579 |
ST14,ITGA6,FLOT1,ERBB2,SLC1A3,PDGFB,CD46,EPCAM,ANK1,ADORA1,CA2,ITGA3,CTNNB1,KCNN4,DLG1,CNNM4,CLDN4,TRPC1,TACSTD2,ERBB3,DLG3,SLC12A2,FLOT2,ABCC1,CASK,EZR,SCRIB,ATP1B1,ERBB2IP,DAG1,EGFR,ENPP1,ATP1A1,LDLRAP1,SLC4A4,ATP7B,NOD2,ARRB1,PKD2,OSCP1,STK39,PROM2 |
| 1.827e-02 | -4.00 | magnesium ion binding | molecular function | GO:0000287 | 194 | 40 | 16491 | 2452 |
PINK1,DYRK3,ENO2,RPS6KA1,ATP9A,ATP8A1,NCS1,ADPRHL1,TOP2A,WEE1,RPS6KA2,PTEN,ALPP,IMPAD1,SRR,MSH2,ATP8B1,HMGCL,MAP3K7,MAST4,MSH6,PGM1,MARK1,FIGNL1,GCLC,ATP8B3,PIF1,PKM,IDH1,MAP3K6,ATP10D,NUDT16,STK26,STK38,PRPS2,PDXK,GEM,MAP3K5,RPS6KA3,MAPK12 |
| 1.829e-02 | -4.00 | IDS (iduronate 2-sulfatase) | protein interactions | 3423 | 40 | 12 | 16036 | 2547 |
ADAMTS2,GUSB,CERCAM,XYLT2,GALNS,PDIA5,CUL1,LOXL2,B3GALNT2,POMGNT2,EXT2,MESDC2 |
| 1.829e-02 | -4.00 | CLN5 (ceroid-lipofuscinosis, neuronal 5) | protein interactions | 1203 | 40 | 12 | 16036 | 2547 |
CALR,NAAA,CYP1A1,ERLEC1,CDS2,SLC25A4,SLC25A13,FBXO6,CDIPT,FBXO27,SLC25A5,ARF4 |
| 1.833e-02 | -4.00 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 39 | 17758 | 2588 |
EXPH5,TMEM184B,SERPINE2,GRIK2,S100A11,HAL,ADO,COL4A5,SORBS3,CRABP2,MERTK,PHF1,PDIA4,CTNNB1,STIM1,GPC3,MANF,PIM1,TLN2,TRAM1,TIAM1,LAMP3,SUN2,DDB2,SEC61B,BNIP3L,ABR,RHEB,PRIM1,IL1R1,SLC6A6,RPL12,PPP2R5A,PRCP,NR4A3,TRAF5,LTA4H,CBX7,GAB1 |
| 1.833e-02 | -4.00 | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP | 192 | 39 | 17758 | 2588 |
RMND5A,TNK1,NUAK1,CTDSPL,DGKA,RASGRP3,GMCL1,GRK6,SAC3D1,RBM23,MDM1,RNF220,SIVA1,PHTF1,BDH1,PASK,MSH2,KANK2,HMGCL,NFU1,MAP3K7,SEPHS1,TRIM8,MMD,ADCK3,MRS2,COX11,GALNT7,ASB13,DAG1,RASA1,ANKRD10,LRIG1,PPM1H,RHOBTB2,MAOA,PLXND1,PPP2R5D,ATMIN |
| 1.833e-02 | -4.00 | GSE17580_TREG_VS_TEFF_DN | MSigDB lists | GSE17580_TREG_VS_TEFF_DN | 192 | 39 | 17758 | 2588 |
EPAS1,IBTK,TBC1D1,DAP,RHBDL3,ARL4C,SPSB1,DENND2D,UHRF1BP1L,ATP6V0B,DOPEY2,CDH1,RALB,FBXL14,TAGLN2,C10orf54,CTSD,CDKN2D,SMAGP,ATG4D,SLC37A1,SYNE2,TCF7,ATP1B1,TANC1,DOCK5,TXNDC11,STK17B,RASGRP2,TXK,PEX5,CDCA4,ACVRL1,STK38,KBTBD2,SETD3,APPL2,OTUB2,FZD5 |
| 1.833e-02 | -4.00 | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_DN | 192 | 39 | 17758 | 2588 |
PLEKHG3,SCN5A,SLC25A24,CRYM,PSME2,SERPINB9,SOD2,RAC2,CARD8,SP100,PPP1R10,KIF14,RPL39,SRR,TRIM21,DIXDC1,IFIT1,ACOX2,MYBL1,RASGRP1,CKS2,TGIF1,ARHGDIB,CD40,FOS,IDH1,IRX3,FAS,OPTN,DDAH1,GPRC5B,DHRS2,TBX1,NAT1,TDRD7,PPP1CB,GLA,RAP1GAP,CD33 |
| 1.833e-02 | -4.00 | GSE17721_LPS_VS_PAM3CSK4_2H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_2H_BMDM_UP | 192 | 39 | 17758 | 2588 |
ARHGEF3,TM2D2,ENO2,TSPAN15,SDC4,KCTD12,MPP5,TEX2,CD274,CYP39A1,TOP2A,HSF2,ZFP36,IL6ST,ALDH7A1,EGLN3,MYLIP,DUSP1,MAP3K3,MX1,SIRT1,PDGFC,PTPN18,SLC37A1,IFIT3,FOS,NIN,TSC1,ETS2,ACYP1,SCG2,RND3,KBTBD2,DCK,SLC27A1,SH3BGRL2,TTC39C,IFIH1,CHPT1 |
| 1.833e-02 | -4.00 | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | 192 | 39 | 17758 | 2588 |
NQO1,AGRN,SLC41A1,NDRG1,EPS8,FHDC1,PSME1,NCKAP1,TRIB2,PHLPP1,DDR1,PRRG4,PPP2R3A,SYDE2,EPCAM,IGF1R,PIK3CA,ZDHHC23,ZMYM1,EGLN3,CPD,NFE2L3,PRODH,ASXL1,BCL9,TNS1,LHFPL2,ABLIM2,NMT2,NFIX,FAS,ZMPSTE24,RGS9,FGF18,RAB11FIP1,S100A5,PPP1CB,MAP3K5,IFIH1 |
| 1.833e-02 | -4.00 | GSE17721_CTRL_VS_LPS_8H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_8H_BMDM_DN | 192 | 39 | 17758 | 2588 |
RUNX2,USH1C,GRHL2,KLHL13,CD82,PDIA5,EFHD2,BCL2L1,SPTB,CARD10,TP73,TIMP1,PSMC2,FBXL14,MDFIC,PTPRE,MYT1,CPD,PMPCB,RHOA,HMGN5,NR4A1,MPP1,FURIN,RAB3IP,PSMA4,ARF4,ARHGAP35,ATXN7L3,PVRL2,NFKBIA,AMMECR1,ITPR1,HDAC1,SERPINI1,MAP3K5,TRAF5,PPP2R2D,JARID2 |
| 1.833e-02 | -4.00 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | 192 | 39 | 17758 | 2588 |
GALK1,PPM1J,GCAT,AK7,NDRG1,ITGA6,SELL,TGFBR1,TP53I11,CNTROB,PATL2,PHLPP1,NUCB2,FAM81A,TMPRSS4,IL17RB,CALR,E2F7,FAM46A,RANBP1,KLC3,TNFRSF18,TMEM64,NEB,GM2A,S100A6,SYPL1,LCA5,DUSP4,SESN1,DAG1,NCOA3,UBE2D2,FAM83D,NR4A3,KPNA2,MELK,CSRP2,RRAGD |
| 1.833e-02 | -4.00 | GSE17721_0.5H_VS_24H_LPS_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_24H_LPS_BMDM_UP | 192 | 39 | 17758 | 2588 |
ANXA3,ERCC6L,GMPR,FAM198B,TRIB2,SEPP1,H1FX,CDKN2C,SCNN1A,PPP4R1,AKR1B1,FBLN5,SHMT1,GUSB,LAP3,ASPM,UXT,LPGAT1,CDC20,SPA17,KIF1C,KLK6,PRRC1,STEAP1,LEPR,DAG1,FOXL1,ZMPSTE24,RND3,TIMM8A,ARRB1,KLF5,MRPS28,PDXK,GLCCI1,AHR,SRSF9,JARID2,TMEM131 |
| 1.838e-02 | -4.00 | PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | MSigDB lists | PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | 146 | 31 | 17758 | 2588 |
PTPN18,DLGAP5,PTPRU,PTPN9,INPP5D,PTPRH,PDIA3,PLD2,DUSP4,SBF1,PGAP1,DUSP5,EPM2A,EDNRA,PTPRF,PLCH1,INPP5E,NT5C2,PTPRJ,PTEN,GDE1,OCRL,DLG1,INPP4B,PLD1,PPP1CA,PDE4D,MINPP1,PTPRE,PLCB2,DUSP1 |
| 1.842e-02 | -3.99 | V$HLF_01 | MSigDB lists | V$HLF_01 | 239 | 47 | 17758 | 2588 |
PRKAA2,NCKAP5,SPRED1,MRC2,TTC39B,GRHL2,TSC22D3,PDGFRL,ANO1,ZFYVE9,GBX2,CDKN2C,ZNF687,CTSC,CDKL5,OCRL,BCL6,PRKG1,KLF9,ACSL4,PDE4D,WNT3A,RASGEF1A,ETV4,STK35,TRIM8,CASK,ING1,DCAF6,LONRF3,SERTAD4,PIK3R1,CDYL,PRICKLE1,CALCRL,EGFR,LEMD2,PELI2,MPP2,RHOBTB2,NFKBIZ,SPRY4,NDST3,TOB1,FOXA1,RPS6KA3,CTDSP1 |
| 1.843e-02 | -3.99 | CAPN2 (calpain 2, (m/II) large subunit) | protein interactions | 824 | 54 | 15 | 16036 | 2547 |
MAN2A2,B3GNT2,ADRBK1,STK26,PAPSS1,NFKBIA,CASP9,CAPNS1,ALDH7A1,TNS1,F2RL1,CDK5R1,DCP2,CTH,PDIA4 |
| 1.843e-02 | -3.99 | genital_tract-extragonadal-germ_cell_tumour-mixed | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-mixed | 29 | 9 | 17775 | 2585 |
MFAP3L,CTNNB1,PTEN,TP53,CABIN1,CBL,IDH1,FLT3,MAP1B |
| 1.845e-02 | -3.99 | ubiquitin binding | molecular function | GO:0043130 | 94 | 22 | 16491 | 2452 |
UFD1L,FAF2,DNAJB2,SPRTN,SHARPIN,C6orf106,MVB12B,HDAC6,TP53INP2,VCP,PER2,OPTN,RAD23A,BCL10,TOP2A,IDE,OTUB2,CRY2,ZRANB1,HSPB1,RNF169,USP16 |
| 1.851e-02 | -3.99 | ENGELMANN_CANCER_PROGENITORS_DN | MSigDB lists | ENGELMANN_CANCER_PROGENITORS_DN | 69 | 17 | 17758 | 2588 |
REC8,LRRFIP2,CITED4,CORO2A,SYBU,SLC35C1,KLK6,SYTL4,PTGFRN,PNKD,CTGF,BMP7,SGK1,FAM102A,FBXO27,HSPA2,OSGIN1 |
| 1.851e-02 | -3.99 | chr9q22 | MSigDB lists | chr9q22 | 69 | 17 | 17758 | 2588 |
SUSD3,SLC35D2,SEC61B,CORO2A,GALNT12,HABP4,ERP44,TGFBR1,ANKS6,SEMA4D,SHC3,ZNF367,NR4A3,TDRD7,EPB41L4B,SYK,CKS2 |
| 1.851e-02 | -3.99 | PID_P75_NTR_PATHWAY | MSigDB lists | PID_P75_NTR_PATHWAY | 69 | 17 | 17758 | 2588 |
CASP3,ADAM17,SORT1,RHOA,AKT1,RIPK2,CASP9,PIK3R1,XIAP,TP53,FURIN,RHOB,IRAK1,NGFRAP1,PRKCI,E2F1,PIK3CA |
| 1.853e-02 | -3.99 | phospholipid biosynthetic process | biological process | GO:0008654 | 222 | 45 | 16441 | 2455 |
PLA2G4A,MTM1,INPPL1,CDS2,INPP5D,PNPLA2,HEXB,ETNK1,PHOSPHO1,PLD2,ISYNA1,PLA2G16,CDIPT,LPIN3,PIGL,PGAP1,CDS1,INPP5E,PTEN,OCRL,SLC44A1,PLCG2,PIK3CA,SLC44A2,PIK3CD,PIKFYVE,FAR1,PIGC,PLSCR1,PLAUR,LPGAT1,PIK3R1,SPTLC2,DGKE,SLC44A3,PI4K2B,AGPAT2,DOLPP1,INPP4B,DGAT2,SLC27A1,SAMD8,PIK3C2B,PLD1,CHPT1 |
| 1.854e-02 | -3.99 | NELSON_RESPONSE_TO_ANDROGEN_UP | MSigDB lists | NELSON_RESPONSE_TO_ANDROGEN_UP | 85 | 20 | 17758 | 2588 |
CPD,NKX3-1,NDRG1,SAT1,SEPP1,MERTK,MYL12A,APPBP2,DNAJB9,UAP1,H1F0,DBI,C1orf21,ALDH1A3,INPP4B,SGK1,STK39,ITGAV,LMAN1,LIFR |
| 1.855e-02 | -3.99 | M Phase | REACTOME pathways | R-HSA-68886 | 296 | 58 | 8202 | 1235 |
SPC25,PSME2,CENPI,PTTG1,NDC80,ERCC6L,CDCA8,PSMD7,KIF23,PSMD10,NUF2,PSME1,KIF2C,LPIN3,CCNB1,SPDL1,CENPN,LMNA,CKAP5,RB1,PSMD1,NUP210,PSMC2,BUB1,KNTC1,NUP85,PSMA5,SMC4,PLK1,ZWINT,CENPA,PSMB4,KIF20A,CENPC,B9D2,CDC20,AURKB,SKA1,CDK1,PSMA4,LEMD2,PPP2R5A,PSMD3,CDCA5,CENPE,NUP37,NDE1,SGOL1,NCAPG2,CCNB2,UBE2C,PSMC1,CNEP1R1,ESPL1,PPP2R5D,PPP2R2D,NUP58,RAD21 |
| 1.856e-02 | -3.99 | Integrin cell surface interactions | REACTOME pathways | R-HSA-216083 | 67 | 17 | 8202 | 1235 |
COL9A3,AGRN,HSPG2,ITGA6,COL18A1,F11R,DAG1,ITGA2B,ICAM1,SPP1,ITGA3,CDH1,ITGB8,COL13A1,ITGA7,ITGAV,COL16A1 |
| 1.857e-02 | -3.99 | G-protein mediated events | REACTOME pathways | R-HSA-112040 | 47 | 13 | 8202 | 1235 |
CALM2,PLA2G4A,ADRBK1,CALM1,ITPR1,GNAL,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2,PRKAR1A |
| 1.859e-02 | -3.99 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | 198 | 40 | 17758 | 2588 |
RMND5A,FARP1,ARAP3,EPS8,CTDSPL,NES,HERC5,GDF15,TEX2,SEPP1,SLC20A1,PHLDA1,DDR1,C11orf95,PLS3,PDGFA,APLP2,CYP1A1,KCNN4,SIVA1,PPME1,FJX1,UBE2J1,TNPO2,ECI2,KANK2,IFIT1,MX1,USP18,MRPS35,DAG1,TP53I3,SFXN1,SLCO4A1,FASTKD1,CSF1,ATP1B3,HSPB1,L1CAM,DLAT |
| 1.865e-02 | -3.98 | skin-other-keratoacanthoma | COSMIC cancer mutations | skin-other-keratoacanthoma | 20 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.865e-02 | -3.98 | keratoacanthoma | COSMIC cancer mutations | keratoacanthoma | 20 | 7 | 17775 | 2585 |
ERBB2,FLT3,FGFR2,EGFR,RET,PIK3CA,TP53 |
| 1.868e-02 | -3.98 | BIOCARTA_TNFR1_PATHWAY | MSigDB lists | BIOCARTA_TNFR1_PATHWAY | 29 | 9 | 17758 | 2588 |
CASP3,RB1,BAG4,TRAF2,PAK2,MADD,ARHGDIB,MAP3K7,LMNA |
| 1.868e-02 | -3.98 | REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM | MSigDB lists | REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM | 29 | 9 | 17758 | 2588 |
GNS,B3GNT7,B3GNT2,HEXB,GLB1,B4GALT4,B4GALT3,ST3GAL1,CHST2 |
| 1.869e-02 | -3.98 | Histidine metabolism | KEGG pathways | hsa00340 | 23 | 8 | 6908 | 1076 |
ALDH3B1,ALDH2,HAL,ALDH1A3,MAOA,ALDH7A1,ALDH3A2,AMDHD1 |
| 1.869e-02 | -3.98 | Histidine metabolism | KEGG pathways | ko00340 | 23 | 8 | 6908 | 1076 |
ALDH3B1,ALDH2,HAL,ALDH1A3,MAOA,ALDH7A1,ALDH3A2,AMDHD1 |
| 1.870e-02 | -3.98 | WANG_LMO4_TARGETS_DN | MSigDB lists | WANG_LMO4_TARGETS_DN | 329 | 62 | 17758 | 2588 |
FBLIM1,FAF2,PAPSS2,MACC1,MRPS15,IQGAP1,BACE1,XIAP,SAMD9,SLC7A2,MGAT5B,SYTL2,DTX3L,RASSF8,SIPA1L2,KIAA0895,GATA2,PAK2,FUT8,ACTA2,VAT1,TNFRSF18,MYH14,HLA-C,PANX2,TMEM64,MYLIP,ATG4D,HMMR,B3GNT7,CASK,HN1L,CRB3,IFITM3,OSTM1,ITCH,ACBD3,DUSP23,RC3H2,FHL2,PDK3,F12,TMTC2,OPTN,AHRR,INSR,RAB11FIP1,INPP4B,AURKA,CTNND1,MRPS28,NFKBIZ,CYP2U1,RNASEL,ATP6V1C1,IFIH1,MAD2L1BP,CPEB2,NRBP1,OCLN,FAM134B,HS6ST3 |
| 1.872e-02 | -3.98 | craniopharyngeal_duct | COSMIC cancer mutations | craniopharyngeal_duct | 409 | 75 | 17775 | 2585 |
LMO7,NF2,DNAJC3,EPHX4,KIF2C,PLXNA1,BARD1,PDGFA,ADPRHL1,CTNNB1,KCNS3,ODF2L,NAGA,SULF2,TEP1,NBPF3,SERTAD3,UTRN,KIF1C,SLC11A2,KIF13A,VCP,SLC44A3,RBM47,PDLIM3,UEVLD,LIMK1,PNPLA6,DHTKD1,RNASEL,ARF6,WBSCR27,BTBD6,PPP2R5D,KDELC2,WASF3,TAOK2,DYRK3,ALDH6A1,CCM2,SLC36A4,COL4A5,ZNF219,RSAD1,SPP1,ITGA3,TAF1B,ATP8B1,MOXD1,ZNF117,NUP85,MYO5A,MED22,ABCC1,PIGC,ADAMTS2,DUSP23,PIP4K2C,OGDHL,PGBD1,PDK3,YES1,AKAP3,PKM,BCAR1,EGFR,GNAS,HTT,PELI2,ZFP30,KBTBD2,APPL2,ARRB1,NR4A2,CDAN1 |
| 1.872e-02 | -3.98 | craniopharyngioma | COSMIC cancer mutations | craniopharyngioma | 409 | 75 | 17775 | 2585 |
LMO7,NF2,DNAJC3,EPHX4,KIF2C,PLXNA1,BARD1,PDGFA,ADPRHL1,CTNNB1,KCNS3,ODF2L,NAGA,SULF2,TEP1,NBPF3,SERTAD3,UTRN,KIF1C,SLC11A2,KIF13A,VCP,SLC44A3,RBM47,PDLIM3,UEVLD,LIMK1,PNPLA6,DHTKD1,RNASEL,ARF6,WBSCR27,BTBD6,PPP2R5D,KDELC2,WASF3,TAOK2,DYRK3,ALDH6A1,CCM2,SLC36A4,COL4A5,ZNF219,RSAD1,SPP1,ITGA3,TAF1B,ATP8B1,MOXD1,ZNF117,NUP85,MYO5A,MED22,ABCC1,PIGC,ADAMTS2,DUSP23,PIP4K2C,OGDHL,PGBD1,PDK3,YES1,AKAP3,PKM,BCAR1,EGFR,GNAS,HTT,PELI2,ZFP30,KBTBD2,APPL2,ARRB1,NR4A2,CDAN1 |
| 1.876e-02 | -3.98 | DLG4 (discs, large homolog 4 (Drosophila)) | protein interactions | 1742 | 119 | 28 | 16036 | 2547 |
DLGAP1,KCNJ12,SCN5A,CASK,GRIK2,FZD4,CIT,GRIN1,ERBB2,IL13RA1,YES1,ERBB2IP,LRRC1,TANC1,FZD7,RAD23A,CD46,FYN,HTT,KIF13B,SIPA1L1,DLG1,MAP3K11,GRIN2D,NRG1,WNT3A,DLG3,MAPK12 |
| 1.876e-02 | -3.98 | protein localization to nucleus | biological process | GO:0034504 | 154 | 33 | 16441 | 2455 |
SUN1,SOX9,TP53,PDIA3,ZFYVE9,LMNA,SIX4,CALR,PPP1R10,BMP7,BCL6,SMO,TNPO2,PIKFYVE,F2R,SYK,NUP85,HES1,SUN2,SEC61B,AKT1,SYNE2,PIK3R1,PRICKLE1,PYGO1,DAG1,HTT,NFKBIA,KPNA2,JAK3,CNEP1R1,TOB1,DRD1 |
| 1.880e-02 | -3.97 | regulation of cellular metabolic process | biological process | GO:0031323 | 5773 | 908 | 16441 | 2455 |
ACACB,TRIM24,IBTK,GRIK2,TRIM5,PNPLA2,DNAJC3,HEXB,RET,XIAP,FBXO2,SMARCAL1,NRG2,IL18,MORF4L2,SNX9,BARD1,CARD10,PHF1,GRM5,ZNF275,TP73,NPM2,CALM2,CDKN2C,DAPK2,PSMD1,TGFBR3,KLF3,DNM2,CRY2,PPP1CA,APOBEC3G,NEK4,VPS11,SMARCA2,TNIP1,UXT,SPRTN,CDA,TFAP2C,PRKAR2B,LOXL2,F12,PPP1R14C,RNF19B,PNKD,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,MID1IP1,CAMK2N2,DNM1L,ANKRD6,LIMK1,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,LSM14B,HSPB1,E2F8,PDPR,GAB1,HOXC13,ZNF720,NUAK1,ITGA6,SOX9,RAB23,LMNA,ELF3,TFAP4,FLII,RAC2,PAIP2B,MEGF8,FBXO7,NEK2,MAP3K9,USP38,USP1,MYDGF,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,PPP6R1,MAPKAPK3,SALL4,STAT4,PYM1,FHL2,MYBL2,CALCRL,ELK1,NPHP3,ILK,TP53INP2,PSMA4,PLIN5,STK17A,NCOA3,FNTA,ETS2,HTT,SEMA4D,SETD3,AURKA,STK39,GDF11,CBX5,SERPINB1,ZNF502,RPS6KA3,TMEM173,XDH,EGLN1,GRHL2,NQO1,INPP5D,ACTR8,PTTG1,WDTC1,PRKACA,CCND1,ST5,CDH1,SP100,DACT1,DLG3,RASGEF1A,CDKN2D,MYT1,ETV4,RNF169,CAMSAP3,PSRC1,RIPK2,APOBEC3D,NRBF2,FZD4,PFKFB2,HTATIP2,CDCA2,PXYLP1,GTF2A2,SNX12,ZNF618,EBF2,NFIX,IRS2,CCNB3,CORO1C,WFS1,WWTR1,RGS14,ARNT,MAPK12,FARP1,TAOK2,TNRC6C,NKX3-1,HSP90B1,PARP14,CKAP2,ESRP1,TRAF2,SDC4,HABP4,FLOT1,GMCL1,PKN1,ZNF219,ETS1,GSTP1,NFAT5,SRPX2,TIPRL,HOXB2,ICAM1,NEO1,CTNNBIP1,DIRAS3,ZFX,PDCD10,IRAK1,CTSC,KNDC1,GPC3,MCF2L,CST3,BAX,PLEKHF1,TMBIM6,WWP1,ZNF230,MAPK11,RAG1,MED22,CRTAP,POU6F1,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,PGBD1,ABLIM2,TXK,PITX2,BTG1,ATXN7L3,ACVRL1,NR1D2,ZFP30,NR4A3,ITGAV,HMGA1,CENPE,OSR1,CD81,USF2,SHOX2,SRSF9,FOXA1,SIGIRR,AGRN,EPAS1,CNOT8,EPHA4,SUDS3,ARFGEF1,LMCD1,NDRG2,NENF,HDAC6,PDGFB,SPTB,FANCI,TFAP2E,PCNA,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,MITF,ELF5,PASK,ABCA2,DUSP10,TNFRSF18,MYBL1,ZNF462,PLK1,THRB,PCGF5,CD55,KCNIP3,CELSR2,CITED4,CBX6,NFE2L1,C12orf65,EZR,EAF2,IDH1,ZBTB7B,CDK1,VCP,OPTN,IRX3,KDM4D,KLF12,ZNF367,HOXA9,PRKCDBP,CTNND1,KLF11,KPNA2,MAFF,RRAGD,PRKAA2,RUNX2,LMTK3,DNAJB2,UBASH3B,RASA2,PDCL,PSMD7,SORBS3,HES2,FBLN1,BMP2,RB1,DAZAP1,TIMP1,IGF1R,GATA2,PAK2,MDFIC,PIM1,WNT3A,PSMA5,USP31,RGMB,ZNF320,STRADB,SCRIB,EIF2AK1,TCF7,ZSCAN12,PDK3,BCL2L13,CDK5R1,FOXD2,MAPKAPK2,CSF1,NLRC5,CDAN1,IFI6,CTBP1,USP43,RAD21,AVPI1,NF2,HOXB7,UPF3B,FOXM1,CTDSPL,TP53,ZNF28,P2RX7,ERBB2,RASGRP3,CCNL1,BAHD1,LPIN3,STIL,EMP2,BCAP31,SYTL2,PER2,RAD23A,IER3,TTC21B,PDGFA,KMT5C,LMO4,PPME1,PLCG2,LHX6,BCL6,CDH3,NOTCH3,OAS3,EGLN3,CTDSP2,DVL2,CTH,SIRT1,PPIF,CLCN3,TIMP2,TCEB2,AKT1,FIGNL1,CDC20,SERTAD3,ACO1,C3orf33,DAG1,MYPOP,PTGS2,ZNF628,DNAJC10,PTPRJ,ATP1A1,IDE,RBL1,PSMD3,STK38,CHMP4B,EFNA5,IRF7,ZBTB6,CNEP1R1,ZNF701,ARFGEF3,CTDSP1,PINK1,CPEB4,MACC1,CD63,TAB3,DAP,GNAL,PSMD10,GTF3A,GDF15,HMGN3,NKRF,CRABP2,AIP,PARM1,SH2D4A,FZD6,PPP2R3A,GBX2,CD109,FOXP2,GTF2F2,TFAP2A,SLC35B4,UBE2J1,SGK1,TRIM21,BUB1,HEXIM2,KLF9,SYK,CAMK2G,TLE6,DUSP1,WBP5,NFE2L3,P2RX4,HES1,FBLN5,RHOA,HMGN5,PSMB4,NR3C1,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,COL7A1,FXR2,MAPK8IP1,USP6,BCL10,CNOT2,DDAH1,BANK1,SERPINA1,TWSG1,ZNF214,CDCA7L,NMI,FGF18,E2F1,PPP2R3C,PKD2,NDFIP1,UBE2C,HIPK3,ZBTB33,PKIA,TXN,PPP4R4,ACVR1,SSH1,LGR4,TSC22D3,CUL1,GATA3,PSME1,CAMK1D,CCNB1,SEPT4,RIC1,PICK1,PAK6,HELZ2,CTGF,ZNF823,ZFP36,RGS3,IL31RA,FOSB,PIK3CA,IRF2,ZBTB18,ACVR1C,PBK,CASP9,CDYL,BNIP3L,AGO4,PIF1,AURKB,SAV1,LDB2,POR,ULK2,AHRR,HLF,AREG,PLK2,TBX1,PPP2R4,PRDM5,EIF4EBP2,NFKBIZ,SERPINI1,MAPK13,SPRY4,F2RL1,TRAF5,LZTS1,DLAT,DDX58,KLF2,CDKN1C,SCOC,DGKQ,PRKAA1,AKAP17A,NOTCH2,PSIP1,SH3RF2,MECOM,CALR,CYR61,BHLHE41,NECAB3,MSH2,DAPK1,SORL1,PIKFYVE,DLX4,ZNF117,GPR161,EEF1D,SOCS5,TRAK2,QSOX1,MMD,ZNF84,MFI2,CALM1,PIP4K2C,WHSC1,KCTD20,NPC2,EPHA1,CYFIP2,KDM3A,NFIB,RASA1,FAS,AP1AR,SERTAD2,PRKAG2,PELI2,NAB2,TCEAL4,ARAP1,FAM83D,PIAS2,SFMBT1,NR4A2,SAMD8,ZBTB34,EFNA1,PER3,MAP3K5,IRF1,ELK4,SPRED1,FOXO6,TCF25,ARMCX3,DLGAP5,S100A11,THRA,RPS6KA1,IQGAP1,SUZ12,CAST,IRX4,EGR3,BCL2L1,FLT3,EPM2A,CD46,APLP2,CCNA2,ZNF75D,RALB,CDKN1B,DAB2IP,PDE4D,OSBPL7,NR2C1,MED30,FOXJ2,DMTN,DRAP1,COX11,PRKCQ,SLC11A2,RAD17,PKMYT1,PYGO1,CBL,H2AFV,SP4,FZD7,ZNF469,PRDM11,ZNF641,FYN,JAK1,PPP2R5A,STK26,NGFRAP1,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,NR3C2,CBX7,ATMIN,PRKAR1A,PCOLCE,DEPDC1,HERC5,PBX3,APOBEC3H,FGF19,TEAD3,SIX4,WWP2,SCML1,SNTA1,E2F7,RNF128,PTEN,DRAM1,SGK3,ATP8B1,ERCC2,ERBB3,CITED2,CNOT6L,MAP3K7,GFI1,TRIM62,SPRY2,MSH6,NCOA2,PDGFC,TGIF1,RASGRF1,CASK,TCFL5,TEF,VAMP3,FURIN,ZKSCAN2,YES1,FOS,GPLD1,CRTC2,CDK5RAP1,TIMP3,FGFR2,PRDX3,TBX18,RYK,SERPINB5,GRIN2D,GPER1,LRRK1,FZD5,CPEB2,ESPL1,USP16,RGMA,JARID2,CCNC,EMX1,CASP3,ST13,CRYM,CAMKK1,VARS2,TAF6L,COMMD5,MAP1LC3B,ERP29,ZFYVE16,EPCAM,HSF2,GRHL1,ZCCHC12,SIVA1,PHTF1,DLG1,ASH2L,ARNT2,CTTN,SLC39A10,RASGRP1,SP5,CYP1B1,SOD1,CXXC5,TRIM8,ASXL1,ASCL5,ITCH,USP18,TYSND1,EDNRA,SEC14L2,MDK,NEIL1,ZNF114,GPRC5B,MADD,IARS2,CAB39,ZNF165,ADIPOR1,SP6,GLA,PSMC1,PPP2R5D,NR2C2,PIFO,PPP1R2,PPP1R12A,ZNF395,SERPINE2,BVES,ETV5,CALM3,TEC,PHLPP1,DUSP5,ZNF432,NOXA1,FAM20C,PRKCI,EBF4,FNIP1,BRAT1,ZNF692,NPTN,C10orf54,RFX5,ACAD8,LRIF1,ETV7,CCDC88A,MDFI,HP1BP3,ELK3,HMG20B,PDE5A,RANBP9,EGFR,SOX13,FECH,GNAS,BCAR3,NUDT16,TSC1,ONECUT1,INSR,PLPP3,NFKBIA,SH3BP4,DCUN1D1,CTSA,JAK3,TOB1,RARG,KLF7,DRD1,PROM2,CCNE2,SORBS1,PAX6,IL15,PSME2,HDAC11,SOD2,IL27RA,OSR2,PATL2,MXD1,SAP130,SS18,SVBP,ZNF687,SETDB2,FRYL,KIF14,SMO,ZBTB49,TWIST1,ECE1,APIP,NFKB2,F2R,HSPA2,UPF3A,FRS3,CHP1,CKS2,MAP3K3,SOAT1,ZNF525,BAG4,TAF5,GLO1,ERBB2IP,SNAPC2,DUSP4,CD40,CDC25C,MAP3K6,PDHX,ARHGAP35,SOCS3,JADE1,HSF4,STAT6,PEX2,TLE1,OVOL1,PTBP3,SPTBN5,AKNA,ABCA1,PPP2R2D,CBX4,GLIS3,ANXA3,ARHGEF11,SH3D19,SERPINB9,LRP4,MIER3,TGFBR1,AES,TRIB2,HMGXB4,HDAC9,ZNF212,IRF2BPL,TOP2A,CARD8,ADORA1,TAF1B,BMP7,MYCL,TOX2,CKS1B,H2AFY,BRD7,KANK2,MXD3,IQGAP3,DCAF6,ADAM17,WNT10B,NR4A1,GCLC,RGCC,MBNL3,RUNX3,TCEAL8,LEPR,FOXL1,MPV17L2,LEMD2,CASP7,SWAP70,PRCP,SPINT2,RAP2C,UBE2D2,TADA2B,ARRB1,HOXB13,SOX8,ZMIZ1,AHR,ABCG1,ZNF596 |
| 1.883e-02 | -3.97 | immune response | biological process | GO:0006955 | 1442 | 243 | 16441 | 2455 |
UNC93B1,TNK1,TXN,LGR4,TRIM5,AK7,TAP1,CUL1,NRG2,GATA3,PSME1,IL18,ITPR2,DPP8,PDGFB,SPTB,TRIM68,CALM2,SUSD2,PSMD1,RPS6KA2,TGFBR3,CTNNB1,SHC3,ELMO2,PSMC2,PIK3CA,DLG1,IRF2,TNFRSF18,TINAGL1,PIK3CD,IL10RB,S100A13,APOBEC3G,IL1RAP,RASGRP1,ERAP2,LAMP3,NLRP4,CD55,TRIM8,ITCH,USP18,CASP9,CR2,AGO4,ARHGDIB,PRKAR2B,F12,PRKRA,RNF19B,LCP1,ENPP1,PLCG1,LIMK1,NOD2,RNASEL,F2RL1,PSMC1,GAB1,PPP2R5D,DDX58,LGALS3,HLA-E,RASA2,HLA-F,PSMD7,CALM3,TEC,NOTCH2,NCKAP1,PHLPP1,DUSP5,IL18R1,MARCH8,IGF1R,GATA2,RPL39,PAK2,MSH2,DAPK1,AHCY,CD70,HLA-C,NCAM1,MAPK7,ULBP2,PSMA5,MAPKAPK3,MICB,CALM1,BTN3A2,TCF7,ELK1,CYFIP2,IFIT3,PSMA4,EGFR,RASA1,FAS,MAPKAPK2,IL1R1,TSC1,SEMA4D,PELI2,PHLPP2,CSF1,NFKBIA,ITPR1,RAET1L,NLRC5,ARPC2,MAP3K5,IFIH1,JAK3,IFI6,RPS6KA3,TMEM173,IRF1,SPRED1,NLRX1,IL15,LFNG,TUBB4B,INPP5D,RPS6KA1,PSME2,TP53,ERBB2,P2RX7,IL27RA,RASGRP3,FTH1,CD274,BCL2L1,PRKACA,EMP2,TNFSF9,APOBEC3B,CD46,PDGFA,SP100,PLCG2,BCL6,CDKN1B,DAB2IP,IFIT1,OAS3,NFKB2,RASGEF1A,LGMN,FRS3,MX1,MBP,RIPK2,AKT1,APOBEC3D,LGALS8,PTGER4,PRKCQ,ITPR3,DUSP4,SOCS3,IRS2,TAPBP,FYN,JAK1,DDOST,PSMD3,AXL,STAT6,SECTM1,STAT1,SPTBN5,IRF7,NRG1,PRKAR1A,OTUD5,ANXA3,HSP90B1,TNRC6C,TAB3,TRAF2,CTSB,SERPINB9,BTN3A1,PSMD10,HERC5,APOBEC3H,PLD2,ETS1,FGF19,ICAM1,HLA-A,CXCL16,ADRBK1,IRAK1,CTSC,PTEN,ADAM15,TRIM21,MAPK11,ERBB3,RAG1,MAP3K7,CNPY3,SYK,TRIM62,CAMK2G,MSH6,RASGRF1,ADAM17,PSMB4,IFITM3,NR4A1,RAPGEF2,PIK3R1,NUB1,RC3H2,GRIN1,RGCC,FBXO9,TRIM35,YES1,FOS,BCL10,TXK,CD83,CTSL,HLA-B,CD8A,SWAP70,FGFR2,FGF18,UBE2D2,DTX4,NR4A3,ERAP1,GRIN2D,GPER1,GEM,ICOSLG |
| 1.884e-02 | -3.97 | Apoptotic execution phase | REACTOME pathways | R-HSA-75153 | 52 | 14 | 8202 | 1235 |
CASP3,FNTA,CASP7,ADD1,CTNNB1,CDH1,STK26,H1F0,DNM1L,PAK2,PRKCQ,BCAP31,LMNA,OCLN |
| 1.885e-02 | -3.97 | OXIDOREDUCTASE_ACTIVITY | MSigDB lists | OXIDOREDUCTASE_ACTIVITY | 281 | 54 | 17758 | 2588 |
TXN,NQO1,ALDH6A1,CYP2J2,BLVRB,SOD2,PDIA5,GMPR,CYB561,SPR,AIFM2,DHRS3,CYP39A1,CYP26A1,P4HB,BDH1,FDXR,ALDH1A3,AOX1,AKR1B1,ALDH7A1,ACOX2,ACAD8,ALDH3A2,TMX1,GPX4,CYP1B1,QSOX1,PRODH,SOD1,ALDH2,CYB5R2,COX11,LOXL2,BLVRA,IDH1,CYP4F3,POR,CYB5A,PRDX4,DHDH,ALDH3B1,ALDH5A1,ACADSB,PRDX3,PLOD2,DHRS2,P4HA2,MDH1,ACADM,PLOD3,CYBRD1,XDH,EGLN1 |
| 1.885e-02 | -3.97 | HISTONE_DEACETYLASE_COMPLEX | MSigDB lists | HISTONE_DEACETYLASE_COMPLEX | 20 | 7 | 17758 | 2588 |
HDAC1,TAF6L,HDAC6,HDAC11,SUDS3,HDAC9,APPL2 |
| 1.885e-02 | -3.97 | WALLACE_PROSTATE_CANCER_UP | MSigDB lists | WALLACE_PROSTATE_CANCER_UP | 20 | 7 | 17758 | 2588 |
PRSS8,GDF15,AHCY,UAP1,ST14,DAP,BDH1 |
| 1.885e-02 | -3.97 | WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP | MSigDB lists | WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP | 20 | 7 | 17758 | 2588 |
CCNE2,PLK1,KPNA2,TMEM8A,NCAPG2,PSMC2,SMC4 |
| 1.885e-02 | -3.97 | MODULE_439 | MSigDB lists | MODULE_439 | 20 | 7 | 17758 | 2588 |
PLK1,PCNA,CCNB1,LAP3,DNAJC3,MYBL2,IER3 |
| 1.885e-02 | -3.97 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | MSigDB lists | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | 20 | 7 | 17758 | 2588 |
ITPR2,ITPR3,ITPKA,DAG1,NFAT5,CAMK2G,ITPR1 |
| 1.885e-02 | -3.97 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | 20 | 7 | 17758 | 2588 |
SPRY4,DUSP4,TRIB2,MOXD1,PHLDA1,PLK2,PKIA |
| 1.885e-02 | -3.97 | WANG_RECURRENT_LIVER_CANCER_UP | MSigDB lists | WANG_RECURRENT_LIVER_CANCER_UP | 20 | 7 | 17758 | 2588 |
DNAJC10,RACGAP1,USH1C,KCNK1,MPHOSPH9,CUL4B,SH3GLB2 |
| 1.885e-02 | -3.97 | TIAN_TNF_SIGNALING_NOT_VIA_NFKB | MSigDB lists | TIAN_TNF_SIGNALING_NOT_VIA_NFKB | 20 | 7 | 17758 | 2588 |
TIPARP,GATA2,NR4A1,MAFF,PTGES,FOSB,IER3 |
| 1.885e-02 | -3.97 | ZHAN_MULTIPLE_MYELOMA_SPIKED | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_SPIKED | 20 | 7 | 17758 | 2588 |
GALNT3,CCND1,IFIT3,CTGF,AREG,TSPAN7,LGALS3BP |
| 1.888e-02 | -3.97 | GGGCATT,MIR-365 | MSigDB lists | GGGCATT,MIR-365 | 107 | 24 | 17758 | 2588 |
LAMP2,ACVR1,PAX6,ARMCX3,SNTB2,PLEKHA7,COL7A1,FAM91A1,ETS1,TP53INP2,SIX4,HDAC9,ADD3,AMMECR1,MYLK,SGK3,BMP1,SGK1,NR4A2,GRAMD1C,MYLIP,NR3C2,SOCS5,TLL2 |
| 1.893e-02 | -3.97 | V$FOXJ2_01 | MSigDB lists | V$FOXJ2_01 | 175 | 36 | 17758 | 2588 |
RUNX2,CPEB4,CHCHD7,FLOT1,TSPAN17,NEO1,SCML1,IER3,FOXP2,KCTD15,HSF2,ARTN,BDH1,KLF3,MITF,SLC44A1,TWIST1,BUB1,NCAM1,NTN1,GFI1,CYP26B1,SSH3,CTNNAL1,SLC39A8,RGAG1,RAB3IP,NFIB,KLF12,COL13A1,PPP1CB,NRG1,C1orf43,CDAN1,PKIA,RGMA |
| 1.894e-02 | -3.97 | ATPase activity, coupled to transmembrane movement of substances | molecular function | GO:0042626 | 105 | 24 | 16491 | 2452 |
ATP8A1,ATP2C2,ABCG4,TAP1,ABCG2,ATP6V1E2,ATP1B1,ABCD4,ATP13A2,TAPBP,ATP6V0B,ATP1A1,ATP7B,ATP13A3,PCYOX1,ABCA2,ABCB1,ABCD1,ATP1B3,ATP6V1C1,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 1.897e-02 | -3.96 | CAGCCTC,MIR-485-5P | MSigDB lists | CAGCCTC,MIR-485-5P | 135 | 29 | 17758 | 2588 |
POU6F1,IER5L,TAOK2,CELSR2,CRB3,TSC22D3,LRP4,DCHS1,RNF165,GRIN1,WDTC1,STRN4,CBX6,TMEM151A,LRRC1,BAHD1,SPTB,DAG1,VPS26A,GLCE,CHPF,KDSR,NUCB1,CAMK2N2,ELMO2,ANKFN1,CDK18,ZMIZ1,NGEF |
| 1.901e-02 | -3.96 | human chrXq21.33 | chromosome location | human chrXq21.33 | 6 | 3 | 26250 | 2805 |
DIAPH2,SYTL4,DIAPH2-AS1 |
| 1.903e-02 | -3.96 | V$FAC1_01 | MSigDB lists | V$FAC1_01 | 210 | 42 | 17758 | 2588 |
OTUD5,BMF,REPS2,HOXB7,EPS8,CALM3,SORBS3,NUP62CL,EFNB1,SIX4,NRP2,HDAC9,CALM2,ITGA3,SRPX,ITGB8,ANKS1B,TMEM62,LHX6,SGK1,CACNA1D,SMARCA2,HN1L,SHARPIN,SAT1,CALM1,NFIB,NFIX,GNAS,PITX2,TAPBP,CAMK2N2,ACADSB,NKD1,FAM117A,KLF11,EFNA1,SEMA3A,NR3C2,CBX4,KLF7,JARID2 |
| 1.910e-02 | -3.96 | MAPK6/MAPK4 signaling | REACTOME pathways | R-HSA-5687128 | 88 | 21 | 8202 | 1235 |
TNRC6C,PSMB4,PSME2,PSMD7,PSMD10,AGO4,MAPK4,PSME1,PRKACA,CDK1,PSMA4,NCOA3,PSMD1,PSMD3,PSMC2,PAK2,RAG1,HSPB1,ETV4,PSMC1,PSMA5 |
| 1.913e-02 | -3.96 | Axon guidance | KEGG pathways | hsa04360 | 127 | 29 | 6908 | 1076 |
DPYSL5,SEMA6B,RHOA,EPHA4,EPHA1,PLXNA1,EFNB1,ABLIM2,RASA1,RND1,PAK6,RAC2,FYN,SEMA4D,DPYSL2,RGS3,LIMK1,PAK2,EFNA5,NTN4,SEMA3G,EFNA1,EPHB4,NTN1,UNC5B,SEMA3A,L1CAM,NGEF,SEMA3B |
| 1.913e-02 | -3.96 | Axon guidance | KEGG pathways | ko04360 | 127 | 29 | 6908 | 1076 |
DPYSL5,SEMA6B,RHOA,EPHA4,EPHA1,PLXNA1,EFNB1,ABLIM2,RASA1,RND1,PAK6,RAC2,FYN,SEMA4D,DPYSL2,RGS3,LIMK1,PAK2,EFNA5,NTN4,SEMA3G,EFNA1,EPHB4,NTN1,UNC5B,SEMA3A,L1CAM,NGEF,SEMA3B |
| 1.915e-02 | -3.96 | endometrioid_adenocarcinoma | COSMIC cancer mutations | endometrioid_adenocarcinoma | 8 | 4 | 17775 | 2585 |
GNAS,PTEN,PIK3CA,TP53 |
| 1.915e-02 | -3.96 | choroid_plexus_papilloma | COSMIC cancer mutations | choroid_plexus_papilloma | 8 | 4 | 17775 | 2585 |
NF2,CTNNB1,IDH1,TP53 |
| 1.915e-02 | -3.96 | penis-carcinoma | COSMIC cancer mutations | penis-carcinoma | 8 | 4 | 17775 | 2585 |
PTEN,EGFR,PIK3CA,TP53 |
| 1.915e-02 | -3.96 | urinary_tract-bladder-other-neoplasm | COSMIC cancer mutations | urinary_tract-bladder-other-neoplasm | 8 | 4 | 17775 | 2585 |
PTEN,PIK3R1,PIK3CA,TP53 |
| 1.915e-02 | -3.96 | cranium | COSMIC cancer mutations | cranium | 8 | 4 | 17775 | 2585 |
AKT1,PTEN,PIK3CA,TP53 |
| 1.915e-02 | -3.96 | central_nervous_system-brain-other-central_neurocytoma | COSMIC cancer mutations | central_nervous_system-brain-other-central_neurocytoma | 8 | 4 | 17775 | 2585 |
AKT1,IDH1,PTEN,TP53 |
| 1.915e-02 | -3.96 | endometrium-hyperplasia | COSMIC cancer mutations | endometrium-hyperplasia | 8 | 4 | 17775 | 2585 |
PTEN,MSH2,PIK3CA,TP53 |
| 1.915e-02 | -3.96 | cervix-carcinoma-endocervical_adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-endocervical_adenocarcinoma | 8 | 4 | 17775 | 2585 |
GNAS,PTEN,PIK3CA,TP53 |
| 1.915e-02 | -3.96 | lung-carcinoma-giant_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-giant_cell_carcinoma | 8 | 4 | 17775 | 2585 |
ERBB2,RB1,CDH1,EGFR |
| 1.915e-02 | -3.96 | giant_cell_carcinoma | COSMIC cancer mutations | giant_cell_carcinoma | 8 | 4 | 17775 | 2585 |
ERBB2,RB1,CDH1,EGFR |
| 1.915e-02 | -3.96 | central_nervous_system-choroid_plexus-other-choroid_plexus_papilloma | COSMIC cancer mutations | central_nervous_system-choroid_plexus-other-choroid_plexus_papilloma | 8 | 4 | 17775 | 2585 |
NF2,CTNNB1,IDH1,TP53 |
| 1.915e-02 | -3.96 | central_nervous_system-parietooccipital-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-parietooccipital-glioma-astrocytoma_Grade_IV | 8 | 4 | 17775 | 2585 |
IDH1,MSH6,MSH2,TP53 |
| 1.915e-02 | -3.96 | central_neurocytoma | COSMIC cancer mutations | central_neurocytoma | 8 | 4 | 17775 | 2585 |
AKT1,IDH1,PTEN,TP53 |
| 1.915e-02 | -3.96 | lung-other-dysplasia-carcinoma_in_situ | COSMIC cancer mutations | lung-other-dysplasia-carcinoma_in_situ | 8 | 4 | 17775 | 2585 |
ERBB2,EGFR,PIK3CA,TP53 |
| 1.915e-02 | -3.96 | endocervical_adenocarcinoma | COSMIC cancer mutations | endocervical_adenocarcinoma | 8 | 4 | 17775 | 2585 |
GNAS,PTEN,PIK3CA,TP53 |
| 1.915e-02 | -3.96 | GACAGGG,MIR-339 | MSigDB lists | GACAGGG,MIR-339 | 64 | 16 | 17758 | 2588 |
THRA,EPHA4,CTDSPL,BLCAP,C3orf18,VCP,ABLIM2,CDK14,BCL6,VAT1,CNNM4,KLF11,FHL1,MAP3K7,TRPC3,USF2 |
| 1.915e-02 | -3.96 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | 64 | 16 | 17758 | 2588 |
PLK1,PRSS23,SOD2,GATA3,SEPP1,S100A2,PHLDA1,LCP1,CSF1,DMWD,HMGA1,KLF9,ETV4,SGCB,ABCA1,CKS2 |
| 1.917e-02 | -3.95 | negative regulation of binding | biological process | GO:0051100 | 121 | 27 | 16441 | 2455 |
ZNF462,EPB41L5,NKX3-1,HABP4,PPARA,NES,AES,AURKB,PDGFB,NFIB,PER2,CTNNBIP1,TFAP4,PTPRF,SP100,RALB,NFKBIA,NEK2,BAX,SMO,E2F1,AURKA,SORL1,TMBIM6,ADAM15,IFIT1,MDFI |
| 1.917e-02 | -3.95 | DNA damage response | WikiPathways | WP707 | 67 | 18 | 4455 | 729 |
CCNE2,DDB2,CASP3,CASP9,TP53,RAD17,CCNB1,CDC25C,SESN1,CDK1,FAS,CCND1,RB1,CCNB3,E2F1,BAX,CDKN1B,CCNB2 |
| 1.922e-02 | -3.95 | Isovaleric acidemia | SMPDB pathways | SMP00524 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | Maple Syrup Urine Disease | SMPDB pathways | SMP00199 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | Isobutyryl-coa dehydrogenase deficiency | SMPDB pathways | SMP00523 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | 3-hydroxyisobutyric aciduria | SMPDB pathways | SMP00522 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | Beta-Ketothiolase Deficiency | SMPDB pathways | SMP00173 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | 3-hydroxyisobutyric acid dehydrogenase deficiency | SMPDB pathways | SMP00521 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | 2-Methyl-3-Hydroxybutryl CoA Dehydrogenase Deficiency | SMPDB pathways | SMP00137 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | 3-Methylcrotonyl Coa Carboxylase Deficiency Type I | SMPDB pathways | SMP00237 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | Methylmalonate Semialdehyde Dehydrogenase Deficiency | SMPDB pathways | SMP00384 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | Propionic Acidemia | SMPDB pathways | SMP00236 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | Isovaleric Aciduria | SMPDB pathways | SMP00238 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | 3-Methylglutaconic Aciduria Type IV | SMPDB pathways | SMP00141 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | 3-Methylglutaconic Aciduria Type III | SMPDB pathways | SMP00140 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | Valine- Leucine and Isoleucine Degradation | SMPDB pathways | SMP00032 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | Methylmalonic Aciduria | SMPDB pathways | SMP00200 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency | SMPDB pathways | SMP00138 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.922e-02 | -3.95 | 3-Methylglutaconic Aciduria Type I | SMPDB pathways | SMP00139 | 30 | 11 | 978 | 190 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,HMGCL,ACADM,ACAD8,MCCC2 |
| 1.923e-02 | -3.95 | HIF-2-alpha transcription factor network | Pathway Interaction DB | hif2pathway | 34 | 13 | 2227 | 480 |
SIRT1,TCEB2,EPAS1,ABCG2,SLC11A2,TWIST1,EFNA1,CITED2,ELK1,EGLN3,ETS1,ARNT,EGLN1 |
| 1.924e-02 | -3.95 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 164 | 34 | 17775 | 2585 |
NCKAP5,CPEB4,RUSC2,EPS8,SMARCAL1,TP53,KIF23,ITPR2,FLT3,S100A2,CDKN2C,PTEN,TACC2,DNM2,PIK3CA,AKR1B1,LIMCH1,EPHB4,ODF2L,SYTL3,HP1BP3,RHOA,AURKB,CBL,IDH1,ADRBK2,SOCS3,SOX13,PLCG1,FYN,TMEM30A,SLC9A6,NKD1,STAT1 |
| 1.926e-02 | -3.95 | axon part | cellular component | GO:0033267 | 174 | 36 | 17570 | 2579 |
BIN1,GRIK2,CALB2,EPHA4,CNTNAP2,KCNC4,ANK1,ADORA1,FLRT3,DPYSL2,DLG1,DAB2IP,GOT1,CPLX1,SCN2A,PACSIN1,HCN3,P2RX4,CLCN3,MBP,SEPT6,GRIN1,SYP,ILK,TANC1,ELK1,DAG1,CNTNAP1,SYT7,SLC9A6,AURKA,NRG1,GPER1,L1CAM,COBL,DRD1 |
| 1.926e-02 | -3.95 | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP | 181 | 37 | 17758 | 2588 |
UNKL,EMX1,BCAM,RAB23,FAM198B,PKN1,SBF1,SPTB,GNB2,WEE1,CDK16,PFKL,MGAT1,CAPG,ADAM15,SGK1,CRY2,AHCY,TMEM8A,LMAN1,NFKB2,FRS3,CDKN2AIP,PRRC1,EPHA1,GINS4,ATP13A2,RGS9,NCOA3,MID1IP1,ACVRL1,FAAH,SH3GLB2,EGFL7,ARPC2,USF2,CBX4 |
| 1.927e-02 | -3.95 | CYCLINKINASE | prints domains | PR00296 | 2 | 2 | 4759 | 661 |
CKS1B,CKS2 |
| 1.927e-02 | -3.95 | GPROTEINAS | prints domains | PR00443 | 2 | 2 | 4759 | 661 |
GNAS,GNAL |
| 1.927e-02 | -3.95 | GLHYDRLASE27 | prints domains | PR00740 | 2 | 2 | 4759 | 661 |
GLA,NAGA |
| 1.927e-02 | -3.95 | MASPIN | prints domains | PR00676 | 2 | 2 | 4759 | 661 |
SERPINB5,SERPINB9 |
| 1.929e-02 | -3.95 | regulation of protein phosphatase type 2A activity | biological process | GO:0034047 | 24 | 8 | 16441 | 2455 |
PPP2R5A,HTT,PPME1,PPP2R4,PPP2R2D,PPP2R5D,TIPRL,PPP2R3A |
| 1.929e-02 | -3.95 | regulation of spindle organization | biological process | GO:0090224 | 24 | 8 | 16441 | 2455 |
PLK1,PSRC1,VPS4B,AURKA,CHMP4B,AURKB,CCNB1,BORA |
| 1.929e-02 | -3.95 | GRB2 (growth factor receptor bound protein 2) | protein interactions | 2885 | 535 | 103 | 16036 | 2547 |
REPS2,HSPG2,TUBB4B,INPP5D,SLC25A13,RPS6KA1,IQGAP1,RET,HEXB,DNAJB11,ERBB2,FTH1,PSME1,FLT3,REPS1,SH3KBP1,SS18,ELMO2,WDR44,SHC3,IL6ST,PSMC2,PIK3CA,DNM2,CDKN1B,CTTN,PDE4D,PPP1CA,TFG,PTPRE,FRS3,CKS2,DOCK4,PTPN18,ITCH,SYP,CBL,SLC25A5,ZBTB7B,DAG1,ARHGAP35,IRS2,PLCG1,FYN,PTPRJ,JAK1,MAP2,AXL,KPNA2,PIK3C2B,SPRY4,GAB1,PRKAR1A,MAPK12,OTUD5,INPPL1,SH3D19,ITGA6,ARHGEF7,UBASH3B,EPS8,SELL,CALM3,AES,RACGAP1,TEC,NCKAP1,MERTK,ITGA2B,SH2D4A,SIRPA,SNTA1,VASP,PIK3AP1,SNX18,CALD1,CD22,OCRL,PAK2,ADAM15,SLAIN2,ERBB3,SPRY2,SYK,EEF1D,DLGAP1,PIK3R1,STRADB,ELK1,CYFIP2,TCEAL8,BCAR1,RASA1,EGFR,GAREM2,INSR,HTT,H1F0,ARAP1,DCUN1D1,FGD6,LRRK1,HIPK3 |
| 1.929e-02 | -3.95 | CLIMENT_BREAST_CANCER_COPY_NUMBER_DN | MSigDB lists | CLIMENT_BREAST_CANCER_COPY_NUMBER_DN | 8 | 4 | 17758 | 2588 |
NRG1,PDGFRL,KIF13B,CASP9 |
| 1.929e-02 | -3.95 | RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_DN | MSigDB lists | RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_DN | 8 | 4 | 17758 | 2588 |
EGFL7,PLXND1,ITGAV,RHOB |
| 1.929e-02 | -3.95 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | MSigDB lists | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | 8 | 4 | 17758 | 2588 |
HLA-B,HLA-C,HLA-F,HLA-A |
| 1.929e-02 | -3.95 | CASTELLANO_HRAS_AND_NRAS_TARGETS_DN | MSigDB lists | CASTELLANO_HRAS_AND_NRAS_TARGETS_DN | 8 | 4 | 17758 | 2588 |
CALCRL,FHL1,CXXC5,IRX3 |
| 1.929e-02 | -3.95 | LE_SKI_TARGETS_DN | MSigDB lists | LE_SKI_TARGETS_DN | 8 | 4 | 17758 | 2588 |
COL18A1,TIMP3,FHL1,DLX4 |
| 1.929e-02 | -3.95 | PEPTIDE_METABOLIC_PROCESS | MSigDB lists | PEPTIDE_METABOLIC_PROCESS | 8 | 4 | 17758 | 2588 |
TAPBP,DNPEP,FURIN,PCSK5 |
| 1.929e-02 | -3.95 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | MSigDB lists | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | 8 | 4 | 17758 | 2588 |
ITPR2,ITPR3,TRPC3,STIM1 |
| 1.929e-02 | -3.95 | MIKKELSEN_DEDIFFERENTIATED_STATE_UP | MSigDB lists | MIKKELSEN_DEDIFFERENTIATED_STATE_UP | 8 | 4 | 17758 | 2588 |
COBL,ETV5,JARID2,PHC1 |
| 1.929e-02 | -3.95 | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_DN | 8 | 4 | 17758 | 2588 |
TLE1,LGALS3,CAST,SOX9 |
| 1.929e-02 | -3.95 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | 8 | 4 | 17758 | 2588 |
EGLN3,NR4A1,E2F1,SGPL1 |
| 1.933e-02 | -3.95 | Signaling by Wnt | REACTOME pathways | R-HSA-195721 | 326 | 63 | 8202 | 1235 |
TNRC6C,LGR4,PSME2,SOX9,XIAP,PSMD7,CUL1,PSMD10,CALM3,AES,PSME1,ZNRF3,ITPR2,KREMEN1,GNB2,FZD6,VPS26A,CALM2,CTNNBIP1,RAC2,PSMD1,CTNNB1,GNB5,DACT1,PSMC2,PRKG1,ASH2L,MAP3K7,WNT3A,PLCB2,DVL2,PSMA5,RHOA,KREMEN2,PSMB4,WNT10B,AKT1,FZD4,BCL9,CALM1,AMER1,PRICKLE1,AGO4,TCF7,SCRIB,PYGO1,ROR1,ITPR3,PSMA4,FZD7,SOX13,CXXC4,PPP2R5A,PSMD3,ITPR1,RYK,TLE1,HDAC1,FZD5,PSMC1,CTBP1,PPP2R5D,RNF146 |
| 1.936e-02 | -3.94 | membrane-enclosed lumen | cellular component | GO:0031974 | 4223 | 662 | 17570 | 2579 |
TRIM24,ADD1,IBTK,AASS,MRPS15,DNAJC3,HEXB,XIAP,SMARCAL1,CCNO,DHX8,TGOLN2,MORF4L2,SYTL4,DPP8,BARD1,PHF1,TP73,NPM2,CALM2,DAPK2,WEE1,PSMD1,RGS12,MUC4,UBE2T,TUBG1,PPP1CA,ACOX2,WBP4,ERAP2,SMARCA2,TNIP1,SPRTN,MTRF1L,TFAP2C,LOXL2,GINS4,COL12A1,LIMK1,HDAC1,MRPS28,RNASEL,PDPR,ANXA11,NXT2,ALDH6A1,GGA1,NUAK1,SOX9,FAM21C,LMNA,GNS,FLII,DNPEP,ZCCHC17,ATP5H,NEK2,FBXL14,CADPS2,USP1,MYDGF,MAPK7,C9orf72,MCCC2,REC8,UFD1L,KIF20A,MAPKAPK3,SALL4,STAT4,PYM1,ERO1A,FHL2,MYBL2,KIF20B,SRSF5,ELK1,ILK,TP53INP2,PSMA4,DCP2,SCARB2,NCOA3,ETS2,TIMM8A,HTT,SETD3,ITPR1,AURKA,GDF11,CFAP20,CBX5,RPS6KA3,GRHL2,ACTR8,ETNK1,PKP2,TESK2,MAPK4,PRKACA,CCND1,RCN1,MUC16,SP100,DACT1,ARL4D,CDKN2D,MYT1,ETV4,RNF169,COL6A2,NRBF2,AGPS,SYNE2,HTATIP2,CDCA2,NUSAP1,RAB38,GTF2A2,PEX5,CCNB3,WWTR1,PDXK,RGS14,GEN1,ARNT,MAPK12,TAOK2,HSP90B1,GCAT,BACE1,ESRP1,DCAF7,SDC4,HABP4,PDIA3,GMCL1,CTSZ,PKN1,TMA16,ETS1,NFAT5,PDIA4,NEO1,CTNNBIP1,DTX3L,ZFX,ADD3,CTSC,ARSG,ANKS1B,GPC3,FAM20B,FDXR,ECI2,MAPK11,AK3,RAG1,TMX1,MED22,CRTAP,PARP9,ACBD5,PLSCR1,BCL9,UBE2A,AK4,RAB11FIP2,ATXN7L3,NR1D2,NR4A3,HMGA1,CMPK2,NUP37,USF2,SRSF9,FOXA1,ACOT7,PHC1,AGRN,EPAS1,CUL4B,SUDS3,ARFGEF1,MCCC1,NDC80,LMCD1,NDRG2,DNAJB11,NENF,HDAC6,PDGFB,SDC1,FANCI,PCNA,RPS6KA2,CTNNB1,P4HB,PSMC2,SLC44A1,DUSP10,SMAGP,PLK1,THRB,PCGF5,ING1,STAU2,CBX6,C12orf65,EZR,ERP44,KLK6,EAF2,PRKRA,ANLN,IDH1,ZBTB7B,CDK1,VCP,OPTN,KDM4D,MSL1,KLF12,MAP2,P4HA2,ZNF367,KPNA2,MAFF,PRKAA2,RUNX2,HJURP,CHCHD7,PSMD7,ASAH1,RACGAP1,RB1,DAZAP1,TIMP1,GATA2,PAK2,MDFIC,FAR2,WNT3A,PSMA5,MRPS33,SPATA13,SCRIB,TCF7,PDK3,G2E3,SMN1,CDK5R1,MAPKAPK2,EPN3,H1F0,COL13A1,P4HA3,ZDHHC7,AKIP1,CCNB2,CTBP1,USP43,RAD21,NF2,HOXB7,UPF3B,FOXM1,P3H2,TP53,RHPN2,CCNL1,BAHD1,PCBP1,SDF4,PER2,TTC21B,PDGFA,KMT5C,TACC2,PLK4,NOTCH3,OAS3,MINPP1,EGLN3,FAR1,CTDSP2,GM2A,SIRT1,PPIF,ERLEC1,TCEB2,AKT1,FIGNL1,CDC20,SERTAD3,DAG1,ATP13A2,DNAJC10,PTGS2,IDE,RBL1,PSMD3,STK38,XRCC3,IRF7,LTA4H,CTDSP1,GSDMD,COL9A3,CMAS,PINK1,PACSIN2,GOLIM4,CD63,TAB3,CTSB,BLVRB,MCTP2,SWI5,CDCA8,ERI2,ERCC6L,PSMD10,GTF3A,NKRF,HMGN3,CRABP2,AIP,DNAJB9,H1FX,GTF2F2,TFAP2A,FAM63A,SGK1,BUB1,ALDH7A1,HMGCL,KLF9,HEXIM2,CAMK2G,HES1,PSMB4,HMGN5,NR3C1,GUSB,PLAUR,LITAF,PPARA,MAML2,COL7A1,BCAR1,DDX23,FUCA1,SERPINA1,NEIL3,CDCA7L,NMI,FGF18,E2F1,PGRMC1,SH3BGRL2,ACADM,UBE2C,PTGES,HIPK3,ZBTB33,DIS3L,GAA,PNISR,TXN,HSPG2,SSH1,FAM129B,GATA3,CUL1,PSME1,CCNB1,OAT,SEPT4,CENPN,HELZ2,RGS3,POLL,IRF2,ZBTB18,LAMP2,LOC81691,CDYL,PIF1,AURKB,SLC25A5,PRIM1,PPP2R4,FAM110C,DLAT,RECQL,DGKQ,KIF23,AKAP17A,NOTCH2,PSIP1,BMP2K,MECOM,SH3RF2,CALR,SNX18,BDH1,MSH2,SORL1,CTSD,EEF1D,GID8,PRODH,DDB2,PMPCB,CEP89,CALM1,WHSC1,VEZT,KDM3A,JADE2,NFIB,PRKAG2,FAM64A,WDR19,APPL2,PIAS2,SFMBT1,CABIN1,NR4A2,ZBTB34,NRBP1,IRF1,ELK4,SPRED1,CEP70,TRIP10,THRA,RPS6KA1,CCDC110,SUZ12,CERCAM,BCL2L1,FLT3,CYHR1,CCNA2,TNPO2,CDKN1B,RNASEH2A,LGMN,MED30,NR2C1,ATG4D,CDKN2AIP,TMEM43,FOXJ2,LYRM1,UTRN,TEP1,PKMYT1,PYGO1,RAD17,ITPR3,H2AFV,ATP10D,SP4,NIN,CEP162,ZNF641,CFAP45,ACAD10,STAT1,PPP1CB,KLF5,NR3C2,CBX7,MRPS9,DEPDC1,CENPI,CBLL1,SPR,TEAD3,AKIRIN1,OXCT1,PHF7,PTEN,PPP1R10,PRC1,ERCC2,MAP3K7,CITED2,CNPY3,GFI1,MSH6,NCOA2,SMC4,PDGFC,TGIF1,PCCB,CASK,ALDH2,PAPD7,FURIN,DIAPH2,FOS,ARSK,CPTP,CRTC2,ACADSB,FGFR2,PRDX3,CSTF2,ERAP1,NCAPG2,ARSB,JARID2,CCNC,CASP3,CRYM,CPT2,UBE2Z,MPP5,TAF6L,ERP29,ECI1,TRIM68,TSEN34,CHPF,GRHL1,ZCCHC12,CDKL5,SIVA1,PHTF1,CAPG,AKR1B1,ANKRD12,ASH2L,NFU1,STK35,SOD1,CXXC5,CENPA,TRIM8,ASXL1,LAP3,MRPS18A,MRPS36,TCN2,NEIL1,GPRC5B,HPSE,TDRD7,TRIM45,IARS2,GLA,PPP2R5D,PSMC1,NR2C2,PCSK5,PPP1R12A,ETV5,CALM3,PM20D2,ADAMTSL4,DUSP5,CES2,COL6A1,SRP54,ZRANB1,ACAD8,LRIF1,ETV7,ELK3,OXR1,HMG20B,PDIK1L,EGFR,SOX13,FECH,NUDT16,UAP1,UTP14C,CDCA5,PAPD5,CTSA,RARG,COL16A1,CCNE2,SORBS1,PAX6,IL15,PSME2,HDAC11,PDIA5,SOD2,COL18A1,MORC4,PHLDA1,SAP130,LRRC45,SETDB2,ETHE1,NFKB2,PDIA6,HSPA2,UPF3A,TAF5,MRPS35,ERBB2IP,SNAPC2,DUSP4,FANCE,CDC25C,PDHX,JADE1,HSF4,ALDH5A1,STAT6,PEX2,TLE1,SGOL1,CBX4,KDELC2,GLIS3,SH3D19,COL4A5,INTS8,HDAC9,IRF2BPL,TOP2A,CARD8,TAF1B,LLGL2,GALNS,TOX2,CKS1B,H2AFY,SUN2,CENPC,NR4A1,SYBU,RC3H2,OGDHL,RUNX3,POLD3,MPV17L2,SPAG1,CTSL,CASP7,TRIM69,HNRNPH2,DHRS2,CTSV,UBE2D2,TADA2B,ARRB1,GLB1,HOXB13,ZMIZ1,AHR,ABCG1 |
| 1.936e-02 | -3.94 | CSR_LATE_UP.V1_UP | MSigDB lists | CSR_LATE_UP.V1_UP | 158 | 33 | 17758 | 2588 |
MZT1,FOXM1,CKAP2,ITGA6,CDCA8,DNAJB11,NUF2,MRAS,KCNC4,TIMP1,GYS1,TUBG1,KIF22,TSPAN13,SLC16A5,TUBA4A,ZWINT,DRAP1,PBK,MYBL2,CCDC34,ANLN,CDK1,CRISPLD2,PRIM1,TIMP3,ZNF367,FAM83D,NETO2,LTBP2,TRPC3,UBE2C,DCBLD1 |
| 1.938e-02 | -3.94 | CANX (calnexin) | protein interactions | 821 | 156 | 35 | 16036 | 2547 |
HSP90B1,LGR4,NDRG1,CD82,SUZ12,ITGA6,PDIA3,FBXO6,BCAP31,HLA-A,CALR,RCN1,PSMC2,RPN2,TECR,LMAN1,WNT3A,PDIA6,ATP2B1,ABCC1,SEC61B,AMFR,GRIN1,ATP1B1,VCP,EGFR,KDSR,DDOST,SERPINA1,APMAP,PGRMC1,KPNA2,PKD2,ACADM,L1CAM |
| 1.943e-02 | -3.94 | STUB1 (STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase) | protein interactions | 10273 | 226 | 48 | 16036 | 2547 |
RUNX2,NQO1,EPAS1,TRAF2,CUL4B,FBXO2,XIAP,TP53,ERBB2,UBE2Q1,TGFBR1,HDAC6,S100A2,TEAD3,EPM2A,PSMD1,IRAK1,PTEN,LLGL2,MITF,SGK1,MAP3K7,HSPA2,PHKG2,S100A6,SEC23A,BAG4,SOD1,AKT1,NR3C1,SH3BGRL,MPP1,PELI3,ILK,VCP,EGFR,AXL,UBE2D2,MAP3K11,ARRB1,CDK18,MAP3K5,FBXO27,HSPB1,NR3C2,AHR,RUSC1,IRF1 |
| 1.944e-02 | -3.94 | BASSO_HAIRY_CELL_LEUKEMIA_DN | MSigDB lists | BASSO_HAIRY_CELL_LEUKEMIA_DN | 80 | 19 | 17758 | 2588 |
ARAP2,TRIM2,PRSS23,CD63,TACC1,RNF11,VAMP3,KCTD12,IL18,FLT3,IL1R1,CCND1,TIMP1,RCBTB2,PLOD2,WWTR1,DAPK1,S100A13,SPRY2 |
| 1.944e-02 | -3.94 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | MSigDB lists | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | 80 | 19 | 17758 | 2588 |
SEC23A,MLEC,MAN1A2,MGAT4B,PDIA3,MCFD2,B4GALT4,CALR,DDOST,MGAT1,MGAT4A,ALG13,DOLPP1,FUT8,RPN2,ALG2,B4GALT3,LMAN1,MGAT5 |
| 1.944e-02 | -3.94 | zinc ion binding | molecular function | GO:0008270 | 1151 | 196 | 16491 | 2452 |
UNKL,TRIM2,TRIM24,TRIM5,XIAP,LMCD1,GATA3,SYTL4,HDAC6,PJA2,CA8,BARD1,PHF1,TRIM68,ZYX,ZCCHC12,PRICKLE3,SIVA1,MKRN3,MARCH2,WBP4,RNF26,MYRIP,CPE,S100A13,APOBEC3G,RASGRP1,ERAP2,THRB,PCGF5,VPS11,SOD1,CXXC5,TRIM8,ING1,RNF11,CDA,RNF165,RNF19B,ZFAND5,TP53I3,PIAS3,CXXC4,MAN2A2,TRIM9,ENPP1,TRIM47,NEIL1,PTER,LIMK1,TRIM45,BMP1,TRAF5,NR2C2,DDX58,LASP1,ZCCHC24,ZNRF3,RABGGTA,SH3RF2,MARCH8,CALR,DNPEP,ZCCHC17,WDFY1,CA2,GATA2,ZNRF2,PRICKLE4,LIMCH1,ZMYM1,ZRANB1,MYLIP,ZNF117,PMPCB,ZNF84,SHARPIN,FHL2,WHSC1,RNF113A,JADE2,ZDHHC3,G2E3,MMP15,ZDHHC20,S100A5,PIAS2,AGBL5,ZDHHC7,NR4A2,ZDBF2,DRP2,IFIH1,RARG,RNF146,CSRP2,KLF7,ADAMTS16,LMO7,RNF224,ZSWIM5,THRA,TP53,MORC4,RNF182,MICALL2,ZNF385B,APOBEC3B,CYHR1,RNF220,ZNF75D,SETDB2,LMO4,ZDHHC12,LHX6,ZDHHC23,VAT1,APIP,MYT1,NR2C1,RNF169,CPD,SEC23A,APOBEC3D,UTRN,SLC11A2,GLO1,PYGO1,CBL,TRIM7,AMZ2,JADE1,IDE,PDLIM3,MMP17,PEX2,ADAMTS14,PDXK,LTA4H,NR3C2,ZC3HC1,ZMAT1,MAN2B2,FBLIM1,TAB3,SHPRH,TRAF2,ERI2,CBLL1,APOBEC3H,ZNF212,ZDHHC21,DTX3L,RNF128,PHF7,ALPP,ZFAND4,ZDHHC13,ADAM15,TRIM3,TRIM21,RAG1,GFI1,TRIM62,S100A6,P2RX4,ADAMTS2,PHF20L1,ADAM17,LONRF3,NR3C1,NR4A1,AMFR,RC3H2,CRIP2,PPARA,PRICKLE1,TRIM35,BLVRA,NEURL1B,RNPEP,ABLIM2,TRIM69,NR1D2,ATXN7L3,NEIL3,ZNF214,DTX4,NR4A3,TADA2B,ERAP1,FHL1,ZMIZ1,USP16,TLL2,PHC1 |
| 1.945e-02 | -3.94 | HR1_rho-bd | interpro domains | IPR011072 | 8 | 4 | 18293 | 2672 |
RHPN2,RTKN2,PKN1,RHPN1 |
| 1.945e-02 | -3.94 | Chromo_dom_subgr | interpro domains | IPR017984 | 8 | 4 | 18293 | 2672 |
CBX5,CBX7,CBX4,CBX6 |
| 1.946e-02 | -3.94 | KEGG_CELL_CYCLE | MSigDB lists | KEGG_CELL_CYCLE | 124 | 27 | 17758 | 2588 |
CCNE2,PLK1,CDKN1C,CDC20,PTTG1,TP53,CUL1,PKMYT1,CCNB1,CDC25C,CDK1,CCND1,CDKN2C,RB1,WEE1,PCNA,CCNA2,CCNB3,RBL1,E2F1,CDKN1B,HDAC1,BUB1,CDKN2D,CCNB2,ESPL1,RAD21 |
| 1.946e-02 | -3.94 | CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | MSigDB lists | CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS | 124 | 27 | 17758 | 2588 |
B3GALT6,GFPT1,GAA,GALK1,UGP2,GNPDA1,GUSB,GNE,XYLT1,ACO1,MGAM,PDK3,IDH1,EXT2,CHST2,EPM2A,GLCE,GNS,IRS2,HS6ST1,HPSE,UAP1,PTEN,PFKL,CSGALNACT1,HS3ST3B1,GAD1 |
| 1.948e-02 | -3.94 | proteasome-mediated ubiquitin-dependent protein catabolic process | biological process | GO:0043161 | 322 | 62 | 16441 | 2455 |
FAF2,HSP90B1,CIT,DNAJB2,JKAMP,PSME2,PTTG1,PSMD7,FBXO2,CUL1,PSMD10,PSME1,FBXO6,CCNB1,DNAJB9,WWP2,RAD23A,PSMD1,KIF14,PSMC2,NEK2,FBXL14,UBE2J1,WWP1,USP38,USP1,STT3B,PSMA5,PLK1,SIRT1,UFD1L,SEC61B,ERLEC1,FBXL16,USP31,PSMB4,ITCH,AMFR,USP18,CDC20,UBE2A,RNF165,FBXO9,AURKB,CCNF,PSMA4,CDK1,VCP,USP6,TRIM9,DNAJC10,PSMD3,WFS1,WWTR1,AURKA,ARRB1,YOD1,UBE2C,PSMC1,USP16,FBXW5,USP43 |
| 1.949e-02 | -3.94 | - | gene3d domains | 3.30.1520.10 | 50 | 14 | 9988 | 1574 |
SNX8,SNX13,SNX18,SGK3,SNX16,PLD2,PIK3C2B,PLD1,SNX9,SNX10,PXDC1,SNX12,SNX30,SNX7 |
| 1.952e-02 | -3.94 | V$USF_Q6_01 | MSigDB lists | V$USF_Q6_01 | 228 | 45 | 17758 | 2588 |
IER5L,LAMP1,HOXB7,TAF6L,SNN,PKN1,GNB2,TFAP4,WEE1,ZFX,KCTD15,ARTN,CDH1,BHLHE41,FAM13B,RANBP1,BAX,ANKRD12,SGK1,STT3B,EPB41L4B,SOCS5,SIRT1,LONRF3,SNTB2,ELOVL3,TFAP2C,TCF7,ELK1,ABR,GNAS,WIPI1,HNRNPH2,UTP14C,KBTBD2,HOXA9,ATP7B,RAB31,SYT13,GLA,C1orf43,STARD13,SLC31A2,NR3C2,RAB3IL1 |
| 1.952e-02 | -3.94 | LCK (LCK proto-oncogene, Src family tyrosine kinase) | protein interactions | 3932 | 135 | 31 | 16036 | 2547 |
CD55,NR3C1,PTPRH,PIK3R1,EZR,PRKCQ,PLD2,CBL,PRKACA,BCAR1,CDC25C,SH3KBP1,RASA1,FAS,SOCS3,PTPRF,CD8A,PLCG1,AXL,PLCG2,PAK2,NFKBIA,DLG1,STAT1,PIK3CA,DNM2,ADAM15,CTNND1,JAK3,SYK,DEF6 |
| 1.953e-02 | -3.94 | pyrophosphatase activity | molecular function | GO:0016462 | 806 | 141 | 16491 | 2452 |
ATP8A1,KLC2,TAP1,SMARCAL1,DHX8,PHOSPHO1,KIF2C,SEPT4,KIF26A,PICK1,ABCD4,RAB15,HELZ2,ENTPD4,DNAH6,ARL1,PSMC2,ATP13A3,ABCA2,DNM2,TUBG1,RAB20,KIF22,MYH14,DDX59,TUBA4A,ATL1,SMARCA2,KIFC2,ARHGDIB,KIF13A,ARFRP1,PIF1,RHEB,VCP,RAB2B,GINS4,ARF4,ENPP1,DNM1L,DOLPP1,ATP7B,PPP2R4,ARF6,RAP1GAP,PSMC1,RRAGD,DDX58,RECQL,PEX6,ABCG2,RAB23,ATP6V1E2,KIF23,RAB6A,MYO5C,RAC2,ATP5H,KIF13B,PCYOX1,MSH2,SRP54,DNAI1,ABCC1,KIF20A,KIF20B,ATP8B3,GNA11,DCP2,RHOB,DHX32,GNAS,NUDT16,RAB31,ATP1B3,KIF12,IFIH1,KIF3C,DYNLRB1,TUBB4B,RALBP1,ATP2C2,ABCG4,MRAS,NUDT12,GNB2,APPBP2,ATP6V0B,RALB,KIF14,ARL4D,RAB27B,MX1,ENPP4,MYO5B,FIGNL1,VPS4B,KIF1C,ATP1B1,RAD17,RAB38,ATP10D,ATP13A2,TAPBP,IDE,ATP1A1,CANT1,XRCC3,RAB29,ABCA1,SHPRH,ATP9A,GNAL,ERCC6L,ARL4C,DNAH3,IFT27,RND1,DIRAS3,KIF5B,TOP2A,GNB5,GTF2F2,KLC3,ATP8B1,ABCD1,ERCC2,MSH6,ATP2B1,MYO5A,RAB3B,RHOA,LONRF3,KIF11,DDX23,RND3,ABCB1,CENPE,ATP6V1C1,GEM,ABCG1 |
| 1.954e-02 | -3.94 | occipital_lobe | COSMIC cancer mutations | occipital_lobe | 34 | 10 | 17775 | 2585 |
NF2,CTNNB1,PTEN,MSH2,TP53,EIF2AK1,IDH1,GNA11,EGFR,MSH6 |
| 1.956e-02 | -3.93 | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDM_UP | 187 | 38 | 17758 | 2588 |
KLF2,HEBP1,RALBP1,TSC22D3,PTTG1,MCOLN3,ARL4C,DGKA,C6orf106,CD274,TSPAN17,CCDC92,WEE1,RABEP2,TMEM51,RFX5,EPB41L5,SUN2,PGM1,RIPK2,SHARPIN,SAT1,CDYL,PLEKHO1,UTRN,BCAR3,TAPBP,GPRC5B,ZNF704,SFMBT1,GRIN2D,IRF7,ATP1B3,RGS14,MIIP,RARG,ANXA11,RRAGD |
| 1.956e-02 | -3.93 | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDM_UP | 187 | 38 | 17758 | 2588 |
DOC2A,MFSD3,CASP3,KLHL13,SHPRH,RALBP1,SMARCAL1,ERCC6L,NOTCH2,ITPR2,KREMEN1,LTBP3,UHRF1BP1L,CAPN2,FAM111A,ENTPD4,KCNN4,BHLHE41,TMEM51,TIPARP,S100A6,MED22,SMC4,MAP3K3,ADCK3,B9D2,EMP3,IFIT3,GIGYF1,PLEKHB1,ATP13A2,ANKRD10,ENDOD1,TAPBP,PRKCDBP,ANXA9,RBM43,NRGN |
| 1.956e-02 | -3.93 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | 187 | 38 | 17758 | 2588 |
ARHGEF3,ZNF395,TSC22D3,ESRP1,EPHA4,TMX4,CYB561,FAM46C,CYP26A1,CDK14,MARCH8,ADD3,MCF2L,SORL1,SGK1,CRY2,SEMA3G,MYBL1,RASGRP1,EEF1D,SMAGP,DUSP1,PCBP3,FOS,RASGRP2,IRS2,TRAM2,SCARB2,TIMP3,MADD,RYK,PPP1CB,NR4A2,TBC1D4,NR3C2,TOB1,ATMIN,KLF7 |
| 1.956e-02 | -3.93 | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 187 | 38 | 17758 | 2588 |
KLF2,LZTFL1,SORT1,JKAMP,XYLT1,TMX4,TGOLN2,INTS8,MGST2,IFT27,REPS1,SAC3D1,CYHR1,SIPA1L2,RPS6KA2,ZNF823,MEGF8,PAPSS1,NFU1,STT3B,PLCB2,PDGFC,PMPCB,ERMP1,MMD,STAU2,OXR1,NDRG3,ZDHHC3,PRIM1,ALDH3B1,PPP2R5A,MTFMT,STK38,PRPS2,ZDHHC7,SLC27A3,RTN3 |
| 1.956e-02 | -3.93 | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN | 187 | 38 | 17758 | 2588 |
CPEB4,CAMKK1,CTSB,DGKA,TGFBR1,CNTNAP2,NCKAP1,FAM91A1,ITPR2,TRIB2,PHLDA1,CARD10,SH3KBP1,ARHGEF10L,EPCAM,PDCD10,TPST1,STT3B,RAG1,MBP,NR3C1,BNIP3L,RAD17,CBL,KDM3A,CYB5A,EDNRA,ZMPSTE24,PTPRF,TMEM50B,PPP2R5A,ETS2,POPDC3,AXL,NAB2,RGS14,EPB41L4A,TMEM131 |
| 1.956e-02 | -3.93 | MEK_UP.V1_DN | MSigDB lists | MEK_UP.V1_DN | 187 | 38 | 17758 | 2588 |
DDX58,COL9A3,ARMCX3,MAN1A2,CALB2,TAP1,EGR3,HERC6,IGF1R,SP100,SLC16A6,ALG13,ATP8B1,IFIT1,OAS3,MINPP1,MYBL1,SNX10,KCTD3,RASGRP1,CYP26B1,DCAF6,ZNF84,LPGAT1,USP18,PRKAR2B,F12,C18orf8,FASTKD1,PTER,MYLK,LRIG1,TDRD7,INPP4B,IRF7,ANXA9,IFIH1,IFI6 |
| 1.956e-02 | -3.93 | GSE14308_TH2_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH2_VS_INDUCED_TREG_UP | 187 | 38 | 17758 | 2588 |
NUDT6,INPPL1,ARAP3,TRIM5,EPS8,BIK,PTTG1,PBX3,PRSS22,SNX9,IFT27,PHF1,AIP,PLS3,CCDC92,KIAA1107,OSBPL3,FAM13B,ECI2,NCEH1,WBP4,LRIF1,SPRY2,ASPM,SH3BGRL,VPS4B,RAD17,SPNS3,BCAR3,IRS2,HS6ST1,AGPAT2,JAK1,SIPA1L1,ERAP1,YOD1,SP6,ARPC2 |
| 1.956e-02 | -3.93 | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | 187 | 38 | 17758 | 2588 |
MRPL44,PPFIBP2,PLA2G16,TNFSF9,AIP,CYP39A1,SSX2IP,BMP2,ENTPD4,ELMO2,CTSC,LMO4,FUT8,DRAM1,LGMN,SYK,FAH,ABCC1,CERS2,TBC1D10B,NAGPA,ORAI2,PTPN18,CBX6,BTN3A2,SLC35C1,CR2,EIF2AK1,CAPNS1,RNPEP,SPAG1,FYN,RBM47,KLF12,SPAG7,STK39,ZMIZ1,HOOK1 |
| 1.956e-02 | -3.93 | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDM_DN | 187 | 38 | 17758 | 2588 |
GCLM,HSP90B1,HJURP,DAP,KCTD12,MRAS,RAB6A,DHRS3,ATP6V0B,VASP,RNF128,XYLT2,SLC44A1,OPN3,UBE2J1,KLF9,IQGAP3,TRAM1,TMBIM1,TMX1,S100A6,MLEC,KIF20A,GUSB,EMP3,RAB38,AKR1E2,STK17B,SNX12,GLCE,PTPRJ,OTUD6B,RAB31,SERPINB5,SERPINB1,ZBTB33,PRKAR1A,HS6ST3 |
| 1.956e-02 | -3.93 | GSE3982_NEUTROPHIL_VS_TH1_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH1_UP | 187 | 38 | 17758 | 2588 |
CCNI,SORBS1,DNAJC3,ARMC7,CUL4B,ERBB2,BTN3A1,DPP8,MXD1,PARM1,SCML1,SNX13,APLP2,ATP6V0B,RAC2,ACAP2,FAM46A,CTGF,TRANK1,FAM63A,ALS2CL,CTDSP2,DOCK4,TRIM8,PFKFB2,NRBF2,TFAP2C,ARHGDIB,LOXL2,IL1R1,SECTM1,SIPA1L1,ARAP1,RYK,ZDHHC7,LTBP2,L1CAM,ARHGEF4 |
| 1.956e-02 | -3.93 | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 187 | 38 | 17758 | 2588 |
CDK17,ARMCX3,NFKBIE,TMEM41B,RASSF7,SOD2,SLC36A4,SNN,PHF1,ICAM1,IER3,SH3D21,CXCL16,ENTPD4,ATP13A3,PRKCI,TIPARP,DOCK4,PAPD7,STAT4,PLAUR,RUNX3,KDM3A,TXNDC11,GINS4,FRMD4B,CD83,MAPKAPK2,CRTC2,ATP1A1,SIPA1L1,NFKBIA,MADD,CHMP4B,HMGA1,ZMIZ1,CBX5,MAFF |
| 1.956e-02 | -3.93 | protein phosphatase type 2A complex | cellular component | GO:0000159 | 20 | 7 | 17570 | 2579 |
PPP2R5A,PPP2R5D,PPP2R2D,PPP2R4,PPP2R3A,NKD1,STRN4 |
| 1.958e-02 | -3.93 | MEL18_DN.V1_DN | MSigDB lists | MEL18_DN.V1_DN | 141 | 30 | 17758 | 2588 |
COL9A3,TRIM2,ALDH6A1,CDH22,ZCCHC24,SH3BGRL,ESRP1,PKP2,PDE5A,NDRG2,CRABP2,SEPP1,FOS,STK17B,EBF2,FRMD4B,IL1R1,DIRAS3,PROM1,SCNN1A,CA2,FAM46A,PTER,TFAP2A,PIK3C2B,SERPINI1,HOXB13,IFIT1,TSPAN1,IFI6 |
| 1.960e-02 | -3.93 | TCR signaling | REACTOME pathways | R-HSA-202403 | 115 | 26 | 8202 | 1235 |
PSMB4,RIPK2,PSME2,INPP5D,PIK3R1,PSMD7,PSMD10,CUL1,PRKCQ,PSME1,PSMA4,BCL10,PLCG1,PTPRJ,PSMD1,VASP,PTEN,PSMD3,NFKBIA,PSMC2,PAK2,UBE2D2,PIK3CA,MAP3K7,PSMC1,PSMA5 |
| 1.962e-02 | -3.93 | AAAYRNCTG_UNKNOWN | MSigDB lists | AAAYRNCTG_UNKNOWN | 348 | 65 | 17758 | 2588 |
LMO7,LTBP1,ACVR1,TSC22D3,BCL2L1,PDGFB,SNX9,PHF1,TRIM68,C11orf84,SESN3,ZNF687,SHC3,ANKRD12,MANF,BTBD3,FGFR1OP2,SMARCA2,TRIM8,C12orf65,PRKCQ,TNS1,ROR1,DUSP4,COL12A1,MAP2,PPP2R4,KLF5,NRG1,CAPN1,SCN5A,SCOC,STRN4,COL4A5,TSPAN7,PPP2R3A,SIRPA,FOXP2,TFAP4,ADD3,ARSG,MGAT1,MGAT4A,KCNK5,NEK2,USP1,KANK2,HEXIM2,CITED2,GFI1,PODXL2,BCL9,TEF,TP53INP2,SPTLC2,NMI,PAPD5,NXPH4,EFNA1,ARPC2,MAP3K5,DEF6,FOXA1,CYBRD1,RNF146 |
| 1.962e-02 | -3.93 | DAIRKEE_TERT_TARGETS_UP | MSigDB lists | DAIRKEE_TERT_TARGETS_UP | 348 | 65 | 17758 | 2588 |
ELK4,EPAS1,THRA,PTTG1,KIF2C,CNTROB,ISOC2,HDAC6,EMP2,GNB2,APOBEC3B,CDKN2C,SIVA1,SEMA3G,CKS2,PPIF,DRAP1,PTGER4,MRPS18A,CDC25C,ZNF618,RTN4RL1,STX10,DDOST,CHMP4B,MLKL,PPP2R2D,CAPN1,LRP4,ABCG2,PDIA3,HMGN3,GSTP1,AIP,LGALS3BP,IRF2BPL,RAC2,CES2,ADRBK1,PAIP2B,CDK16,ATP5H,BAX,ECI2,ALDH7A1,MAPK11,CNPY3,ALDH3A2,PMPCB,SHARPIN,HMG20B,COL7A1,DCP2,COL13A1,C1orf21,DBI,FAM83D,PGRMC1,SLC4A3,SSNA1,PLOD3,ARHGEF9,DEF6,ARHGEF4,CD33 |
| 1.962e-02 | -3.93 | KIF5A (kinesin family member 5A) | protein interactions | 3798 | 27 | 9 | 16036 | 2547 |
KIF5B,INSR,RAPGEF2,KLC2,KLC3,KIF11,NCOA2,SMN1,TRAK2 |
| 1.962e-02 | -3.93 | TRMT2A (tRNA methyltransferase 2 homolog A) | protein interactions | 27037 | 27 | 9 | 16036 | 2547 |
PASK,IRF7,ATP1B1,DMWD,SMN1,DCP2,RASA1,EGFR,IRF1 |
| 1.962e-02 | -3.93 | PDE6D (phosphodiesterase 6D, cGMP-specific, rod, delta) | protein interactions | 5147 | 27 | 9 | 16036 | 2547 |
RHOA,CUL1,FAM219A,RPGR,RHEB,RASA1,RHOB,RND1,RAD23A |
| 1.962e-02 | -3.93 | RGS3 (regulator of G-protein signaling 3) | protein interactions | 5998 | 27 | 9 | 16036 | 2547 |
SCN5A,PAX6,PLSCR1,RGS3,ARRB1,HIPK3,EFNB1,GNA11,MAPK12 |
| 1.965e-02 | -3.93 | V$SP1_Q2_01 | MSigDB lists | V$SP1_Q2_01 | 234 | 46 | 17758 | 2588 |
LASP1,HOXB7,GGA1,THRA,CAMKK1,ETV5,BAHD1,TIPRL,NFAT5,SIX4,PPP2R3A,CHPF,MECOM,APLP2,ZNF687,SNX18,ZFP36,BHLHE41,FUT8,SRR,BCL6,ANKRD12,CDH3,ERBB3,NOTCH3,CACNA1D,CAMK2G,TEF,LYRM1,NFE2L1,CLSTN1,PDIK1L,CDK5R1,RAB2B,PIAS3,ONECUT1,ARHGEF19,PTPRJ,CORO1C,MAP3K11,AGBL5,NXPH4,PITPNA,STARD13,RTN3,KLF7 |
| 1.972e-02 | -3.93 | Glycosaminoglycan degradation | KEGG pathways | ko00531 | 19 | 7 | 6908 | 1076 |
GNS,GLB1,HPSE,ARSB,GUSB,GALNS,HEXB |
| 1.972e-02 | -3.93 | Glycosaminoglycan degradation | KEGG pathways | hsa00531 | 19 | 7 | 6908 | 1076 |
GNS,GLB1,HPSE,GUSB,ARSB,GALNS,HEXB |
| 1.973e-02 | -3.93 | MASSARWEH_RESPONSE_TO_ESTRADIOL | MSigDB lists | MASSARWEH_RESPONSE_TO_ESTRADIOL | 59 | 15 | 17758 | 2588 |
IL17RB,TOP2A,ADD3,IGF1R,PRSS23,AREG,MAP2,AMFR,SYBU,LRIG1,EGR3,GLA,MYBL1,TIPARP,STARD13 |
| 1.973e-02 | -3.93 | APOPTOTIC_PROGRAM | MSigDB lists | APOPTOTIC_PROGRAM | 59 | 15 | 17758 | 2588 |
TOP2A,CASP3,SOD1,CASP7,DNM1L,CASP9,BIK,STAT1,TP53,BAX,BCL2L1,AIFM3,F2R,IFI6,VCP |
| 1.973e-02 | -3.93 | glycerophospholipid metabolic process | biological process | GO:0006650 | 246 | 49 | 16441 | 2455 |
PLA2G4A,MTM1,INPPL1,CDS2,INPP5D,TMEM55B,PNPLA2,ETNK1,PHOSPHO1,PLD2,PLA2G16,CDIPT,LPIN3,PIGL,PGAP1,CDS1,INPP5E,PTEN,OCRL,IMPAD1,SLC44A1,PLCG2,SERINC2,PIK3CA,SLC44A2,PIK3CD,PIKFYVE,FAR1,PIGC,PLSCR1,PLAUR,LPGAT1,PIK3R1,PIP4K2C,SLC44A3,GPLD1,PI4K2B,ALDH5A1,AGPAT2,ABHD12,DBI,PLA2G15,INPP4B,PNPLA6,DGAT2,SLC27A1,PIK3C2B,PLD1,CHPT1 |
| 1.974e-02 | -3.92 | DOK1 (docking protein 1) | protein interactions | 1796 | 45 | 13 | 16036 | 2547 |
PLCG1,FYN,INSR,INPP5D,PTPRH,RET,PIK3R1,ERBB2,CBLL1,TEC,YES1,RASA1,EGFR |
| 1.974e-02 | -3.92 | PPM1A (protein phosphatase, Mg2+/Mn2+ dependent, 1A) | protein interactions | 5494 | 45 | 13 | 16036 | 2547 |
INPPL1,CTNNB1,AKT1,FGFR2,NR4A1,PRKAA1,PIK3R1,PRKCI,ARRB1,PRSS22,PKN1,HSPB1,DVL2 |
| 1.975e-02 | -3.92 | Synthesis of PIPs at the plasma membrane | REACTOME pathways | R-HSA-1660499 | 33 | 10 | 8202 | 1235 |
MTM1,PI4K2B,INPPL1,PTEN,INPP5D,PIK3R1,INPP4B,PIK3CA,PIK3C2B,PIK3CD |
| 1.975e-02 | -3.92 | Cargo concentration in the ER | REACTOME pathways | R-HSA-5694530 | 33 | 10 | 8202 | 1235 |
SEC23A,SERPINA1,AREG,CTSC,LMAN2L,CTSZ,COL7A1,LMAN1,MCFD2,TMED2 |
| 1.976e-02 | -3.92 | V$SMAD_Q6 | MSigDB lists | V$SMAD_Q6 | 240 | 47 | 17758 | 2588 |
CCNI,LTBP1,NCKAP5,BMF,ARAP3,RUNX2,ATP6V1E2,UBE2Q1,PDGFB,DUSP5,SH3KBP1,PPP1R10,KCNN4,CALD1,LHX6,CKS1B,TWIST1,TINAGL1,PIM1,NOTCH3,FGFR1OP2,ZNF462,UFD1L,ELK3,PIK3R1,DCHS1,SERTAD3,ARHGDIB,PTGFRN,SNX12,PRX,C11orf45,MAGED2,PIAS3,ARHGEF19,SLC25A4,DDOST,C1orf21,TSPAN18,SERPINB5,NXPH4,GRIN2D,CBX5,NRGN,HOXC13,SNPH,PHC1 |
| 1.977e-02 | -3.92 | INTEGRAL_TO_MEMBRANE | MSigDB lists | INTEGRAL_TO_MEMBRANE | 1271 | 211 | 17758 | 2588 |
LAMP1,BCAM,ACVR1,GRIK2,SLC25A13,EPHA4,SLC20A1,SDC1,SLC9A7,GRM5,ABCD4,HTR1D,ZYX,TGFBR3,ENTPD4,TM9SF2,STIM1,LMAN2L,IL6ST,SLC44A1,STEAP2,FUT1,ABCA2,TRPC1,CLDN4,TACSTD2,PXMP4,TRAM1,IL10RB,IL1RAP,SGCE,CD55,MCTP1,ACVR1C,ROR1,SLC17A5,SLC25A5,PLEKHB1,EDNRA,ENPP1,HS6ST1,KCNMB4,SLC25A4,KCNK1,GDE1,DOLPP1,ATP7B,MADD,POMT1,SLC31A2,F2RL1,CD99,FXYD3,ABCG2,NOTCH2,B4GALT4,MERTK,TSPAN7,ITGA3,KCNN4,SLC16A6,CD22,ICAM5,OPN3,FXYD5,SORL1,CD70,CNGA1,NCAM1,SLC12A2,TMED2,CKAP4,KDELR1,ABCC1,NAGPA,FADS2,QSOX1,PODXL2,PCDH1,MMD,MFI2,PTPRH,CALCRL,EPHA1,BCL2L13,STEAP1,PTPRF,MMP15,IL1R1,GABRD,SCARB2,INSR,SLC4A4,ITPR1,SLC4A3,MPP2,OSMR,EFNA1,ATP1B3,TRPC3,DRD1,SLC2A4,IL15,ST14,SLC2A8,CD82,P2RX7,PKP2,IL27RA,IL13RA1,SLC7A2,EMP2,FLT3,DDR1,BCAP31,KTN1,CD46,ATP6V0B,SMO,VAT1,NOTCH3,EPHB4,ECE1,LMAN1,TSPAN1,F2R,CLCN3,PTPRU,FZD4,PTGER4,IGSF8,SLC11A2,ATP1B1,CD40,DAG1,FZD7,TAPBP,ATP1A1,PTPRJ,PTK7,WFS1,AXL,MMP17,SLC9A6,PEX2,SECTM1,HS3ST3B1,LIFR,ABCA1,GOLIM4,TRAPPC10,MPZL1,CD63,TSPAN15,BACE1,MAN1A2,MCTP2,FLOT1,GABRG2,SELL,CYB561,TGFBR1,JAG2,SBF1,KCNC4,LBR,EFNB1,SLC9A2,ICAM1,FZD6,XPR1,NEO1,M6PR,IL17RB,ADORA1,ITGB8,MGAT1,KCNK5,GPC3,BAX,SLC44A2,TMBIM6,TSPAN13,ERBB3,SGCB,SLC16A5,SLC35A1,ATP2B1,GCNT1,P2RX4,SYPL1,ADAM17,MPP1,AMFR,VAMP3,GRIN1,CD83,BCL10,GALNT3,CNTNAP1,PROM1,ACVRL1,SPINT2,PGRMC1,RYK,ABCB1,PKD2,FZD5,CD81,GOLGB1,CD33 |
| 1.978e-02 | -3.92 | astrocyte projection | cellular component | GO:0097449 | 8 | 4 | 17570 | 2579 |
EZR,PINK1,ADGRG1,GRM5 |
| 1.978e-02 | -3.92 | zonula adherens | cellular component | GO:0005915 | 8 | 4 | 17570 | 2579 |
CAMSAP3,SORBS1,PVRL2,PLEKHA7 |
| 1.978e-02 | -3.92 | Glucagon signaling pathway | KEGG pathways | hsa04922 | 101 | 24 | 6908 | 1076 |
SIRT1,PRKAA2,ACACB,AKT1,CALM1,PRKAA1,PPARA,CALM3,PYGL,ITPR2,PKM,ITPR3,PRKACA,GNAS,CRTC2,CALM2,PRKAG2,PFKL,ITPR1,GYS1,PHKA2,PLCB2,PHKG2,CAMK2G |
| 1.978e-02 | -3.92 | Glucagon signaling pathway | KEGG pathways | ko04922 | 101 | 24 | 6908 | 1076 |
SIRT1,PRKAA2,ACACB,AKT1,CALM1,PRKAA1,PPARA,CALM3,PYGL,ITPR2,PKM,ITPR3,PRKACA,GNAS,CRTC2,CALM2,PRKAG2,PFKL,ITPR1,GYS1,PHKA2,PLCB2,PHKG2,CAMK2G |
| 1.982e-02 | -3.92 | BIOCARTA_GPCR_PATHWAY | MSigDB lists | BIOCARTA_GPCR_PATHWAY | 34 | 10 | 17758 | 2588 |
GNAS,CALM2,PLCG1,CALM1,CALM3,PRKAR2B,ELK1,FOS,RPS6KA3,PRKAR1A |
| 1.982e-02 | -3.92 | XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | MSigDB lists | XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | 34 | 10 | 17758 | 2588 |
FYN,CDK17,UAP1,TIMP1,ECE1,FHL1,HMGA1,ITPKA,ITPR3,PHLDA1 |
| 1.982e-02 | -3.92 | PID_EPHA_FWDPATHWAY | MSigDB lists | PID_EPHA_FWDPATHWAY | 34 | 10 | 17758 | 2588 |
PLCG1,FYN,RHOA,EPHA4,EFNA5,EFNA1,EPHA1,YES1,CBL,NGEF |
| 1.984e-02 | -3.92 | GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP | 193 | 39 | 17758 | 2588 |
NFKBIE,ARFGEF1,TRAPPC8,GPR180,SEPP1,FLT3,IFT27,APPBP2,EFR3A,MGAT4A,SLC30A6,GTF2F2,TNFRSF18,SGCB,SYK,GM2A,B3GALT6,PSMB4,PLSCR1,LAP3,ITCH,STAT4,PARD3B,KIF1C,DIAPH2,LRRC1,PSMA4,ATP13A2,AMZ2,TRIM47,TRAM2,PEX5,CASP7,CORO1C,NLRC5,PPM1H,PKD2,RPS6KA3,IRF1 |
| 1.984e-02 | -3.92 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_DN | 193 | 39 | 17758 | 2588 |
CCDC109B,ATP8A1,DGKA,ITPR2,GPSM2,NCKAP1,CARD10,SYTL2,IL17RB,CDKN2C,EPCAM,CCNA2,NEK2,RTKN2,NOTCH3,EPB41L4B,RAG1,CDKN2D,SYTL3,PLK1,PCCB,B3GNT2,CENPA,PBK,MPP1,TNFAIP8L1,PRKCQ,ATP1B1,BLVRA,SKA1,GINS4,DGKE,PTPRF,FAM64A,ETS2,DYSF,AURKA,GLCCI1,STARD3NL |
| 1.984e-02 | -3.92 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | 193 | 39 | 17758 | 2588 |
CYP2J2,DNAJB2,DGKA,MCCC1,TP53,SELL,KCTD12,MGST2,FAM101B,SIPA1L2,IGF1R,RALGPS2,KCNN4,ZFP36,IL6ST,SLC44A1,FAM102A,TSPAN13,CNGA1,NR2C1,EPHX1,P2RX4,PCCB,CASK,CXXC5,SLC11A2,TCF7,RAB3IP,FAM109A,SESN1,ANKRD10,TAPBP,ETS2,ACYP1,WFS1,NR4A3,ARRB1,FAM134B,ABCG1 |
| 1.984e-02 | -3.92 | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN | 193 | 39 | 17758 | 2588 |
AGRN,IL15RA,IL15,SERPINB9,TAP1,ETNK1,POMGNT1,LGALS3BP,AKIRIN1,ZFYVE16,PSMD1,GTF2F2,TRIM21,PIM1,HLA-C,NFKB2,GFI1,FAH,MX1,IFITM3,USP18,RNF11,CASP9,FURIN,IFIT3,RNF19B,CASP4,RHOB,HLA-B,TAPBP,SHROOM3,NMI,E2F1,STAT1,IRF7,CMPK2,IFIH1,UBE2C,ABCA1 |
| 1.984e-02 | -3.92 | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDM_UP | 193 | 39 | 17758 | 2588 |
CHCHD7,MRPS15,HEBP1,DAP,SLC25A13,GNE,NDUFA4,FAM91A1,ELF3,PCNA,CCNA2,CDH1,TM9SF2,ELMO2,CDK16,KCNN4,RDH14,OPN3,SRR,PCYOX1,FAM63A,TSPAN13,TECR,SPRY2,ALDH3A2,P2RX4,MBP,KIF20A,HTATIP2,LRRC1,ANLN,PNKD,ZMPSTE24,LDLRAP1,PRDX3,NR4A3,CCNB2,GLCCI1,FAM134B |
| 1.984e-02 | -3.92 | GSE7764_NKCELL_VS_SPLENOCYTE_DN | MSigDB lists | GSE7764_NKCELL_VS_SPLENOCYTE_DN | 193 | 39 | 17758 | 2588 |
DYRK3,ZNF395,DGKA,KIF23,TRIB2,MERTK,SNX9,TOP2A,RB1,ANK1,CASC4,PPME1,BDH1,NEK2,ADAM15,GOT1,APIP,TMEM64,TECR,LGMN,MYO5A,EPHX1,SNX8,CLCN3,PLEKHO1,SERTAD3,EIF2AK1,CCNF,GTF2A2,RANBP9,CYP4F3,AMZ2,PLCG1,TMEM50B,PLIN3,CEP41,CD81,APOL2,SNX30 |
| 1.985e-02 | -3.92 | V$OCT_C | MSigDB lists | V$OCT_C | 246 | 48 | 17758 | 2588 |
PAX6,SCOC,THRA,TSC22D3,IRX4,MRAS,DSE,TEAD3,SLC25A35,PPP2R3A,CDK14,PER2,HDAC9,SESN3,ADORA1,PTEN,CYR61,DPYSL2,LHX6,FBXL14,CNNM4,TSPAN13,MANF,PDE4D,DGKG,WBP5,PLEKHA6,ING1,FZD4,SH3BGRL,SERTAD4,STAT4,KIF13A,LDB2,ITPR3,RHOB,DPYSL3,TSC1,FGFR2,MMP17,FAM117A,PPP2R3C,TMOD2,SP6,ARHGAP4,JARID2,NXT2,TLL2 |
| 1.988e-02 | -3.92 | HAD-like_dom | interpro domains | IPR023214 | 80 | 19 | 18293 | 2672 |
CMAS,ATP9A,ATP8A1,ATP2C2,CTDSPL,PHOSPHO1,ATP8B3,LPIN3,ATP10D,ATP13A2,NT5C2,ATP1A1,ACAD10,ATP7B,ATP13A3,ATP8B1,CTDSP2,ATP2B1,CTDSP1 |
| 1.990e-02 | -3.92 | positive regulation of small GTPase mediated signal transduction | biological process | GO:0051057 | 38 | 11 | 16441 | 2455 |
RASGRF1,ADGRG1,CSF1,ARRB1,ERBB2,NRG1,NOTCH2,RASGEF1A,F2R,F2RL1,RASGRP1 |
| 1.990e-02 | -3.92 | spindle localization | biological process | GO:0051653 | 38 | 11 | 16441 | 2455 |
CENPA,HTT,LLGL2,ASPM,NDC80,NUSAP1,GPSM2,NDE1,SPDL1,SPRY2,ESPL1 |
| 1.990e-02 | -3.92 | regulation of nucleotide catabolic process | biological process | GO:0030811 | 38 | 11 | 16441 | 2455 |
PRKAA2,INSR,PRKAG2,PRKAA1,PPARA,TP53,P2RX7,MAPK7,ARNT,EGLN1,IER3 |
| 1.990e-02 | -3.92 | cytoplasmic sequestering of protein | biological process | GO:0051220 | 38 | 11 | 16441 | 2455 |
PINK1,NFKBIE,AKT1,THRA,NFKBIA,KDELR3,PSMD10,PDIA3,PKD2,KDELR1,MDFI |
| 1.992e-02 | -3.92 | PRKCB (protein kinase C, beta) | protein interactions | 5579 | 99 | 24 | 16036 | 2547 |
DDX58,MBP,IBTK,HABP4,GRIN1,GABRG2,RASGRP3,CDK1,EGFR,GRM5,TOP2A,RB1,ADRBK1,H1F0,PPP2R4,GRIN2D,PPP1CA,NCAM1,NRGN,TIAM1,AFAP1,DVL2,OCLN,GCNT1 |
| 1.993e-02 | -3.92 | V$LYF1_01 | MSigDB lists | V$LYF1_01 | 252 | 49 | 17758 | 2588 |
ENO2,IGFBP6,RASA2,RHBDL3,IRX4,NRG2,BAHD1,TNFRSF19,PRR7,GNB2,ATP6V0B,PDCD10,IGF1R,RALGPS2,CALD1,XYLT2,GPC3,FUT8,EPB41L4B,PLCB2,NCOA2,ZNF462,HES1,CXXC5,ASXL1,SLC39A8,PANK1,SYNE2,FURIN,SERTAD3,TFAP2C,PRICKLE1,PELI3,PTPRF,PITX2,MPRIP,ITGA7,PAPD5,BMP1,SERPINI1,ANXA9,NRGN,PPP2R5D,NR3C2,RTN3,RARG,CBX4,JARID2,DMPK |
| 1.994e-02 | -3.92 | central_nervous_system-brain-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma_Grade_II | 75 | 18 | 17775 | 2585 |
AKT1,RET,PIK3R1,TP53,TEP1,ERBB2,PLXNA1,IDH1,GNA11,EGFR,GNAS,CDKN2C,RB1,MUC16,CTNNB1,PTEN,PIK3CA,AKNA |
| 1.999e-02 | -3.91 | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | MSigDB lists | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | 102 | 23 | 17758 | 2588 |
SHMT1,CEP89,GCLC,POC1B,SUZ12,CBLL1,MRPS18A,CYFIP2,TRIB2,CENPN,CDK1,TYSND1,MDM1,CDCA4,DCK,RANBP1,FAM20B,OTUB2,DAB2IP,AHCY,EIF4EBP2,TRAF5,SEPHS1 |
| 2.005e-02 | -3.91 | extracellular region | cellular component | GO:0005576 | 4445 | 695 | 17570 | 2579 |
KLK10,IL15RA,DNAJC3,HEXB,FBXO2,NRG2,LGI3,IL18,LYNX1,SNX9,CMTM6,LTBP3,GRM5,EPDR1,CALM2,NAPG,PSMD1,TGFBR3,MUC4,CABP1,ALDH1A3,DNM2,CRY2,SEMA3G,PPP1CA,MANF,TINAGL1,IL10RB,CPE,MGAT5,TUBA4A,SH3BGRL,DSTN,RNF11,CDA,PRKAR2B,LOXL2,F12,ARF4,LCP1,COL12A1,PGF,ENPP1,CARHSP1,BOLA3,MYLK,SERPINB6,ARF6,HSPB1,ANXA11,ALDH6A1,CYP2J2,ITGA6,RAB23,MERTK,TTYH3,GNS,RAC2,SH3D21,DNPEP,CD22,MEGF8,ATP5H,FLRT3,PCYOX1,MYDGF,NCAM1,ULBP2,C9orf72,PLS1,MEST,GNA11,PSMA4,RHOB,CYB5A,C11orf45,PTPRF,IL1R1,NAAA,SCARB2,NCOA3,SLC4A4,SEMA4D,APMAP,DYSF,MDH1,B4GAT1,MAL2,GDF11,ARPC2,CFAP20,SERPINB1,XDH,ADAMTS16,MTM1,NQO1,TUBB4B,LFNG,CD82,APOO,PRSS22,MVB12B,PRKACA,TNFSF9,MUC16,SCNN1A,CDH1,ENPP5,TAX1BP3,ACSL4,DLG3,RAB27B,ENPP4,C6orf1,COL6A2,LGALS8,FZD4,SYNE2,CYS1,VPS4B,SNX12,ALDH3B1,AXL,PDXK,GEN1,ISOC1,GALK1,CTHRC1,HSP90B1,MAN1A2,SDC4,HABP4,FLOT1,PDIA3,CTSZ,NUCB2,GSTP1,SRPX2,ICAM1,CAPN2,CXCL16,PDCD10,FUT2,ITGB8,CTSC,ARSG,GPC3,MCF2L,MGAT4A,CST3,TUBGCP6,BAX,ADAM15,WWP1,IGFBP2,ITM2C,S100A6,CRTAP,PVRL4,ADAMTS2,PLSCR1,DUSP23,GRIN1,PLEKHA7,AK4,BLVRA,CRISPLD2,GALNT3,RPL12,PROM1,PLOD2,SYT7,DBI,FAM3C,PLA2G15,ITGAV,CD81,CYBRD1,ACOT7,TLL2,BCAM,AGRN,GNPDA1,CUL4B,LMCD1,NDRG2,F11R,NENF,GALM,PDGFB,SDC1,SLC9A3R2,SUSD2,CPNE2,PCNA,TM9SF2,CTNNB1,NPNT,P4HB,IL6ST,ARL1,PAPL,SLC44A1,RBBP8NL,TNFRSF18,NTN4,NEB,S100A13,THRB,CD55,CR2,EZR,ERP44,KLK6,IDH1,CDK1,VCP,RHEB,DPYSL3,KDM4D,ARRDC1,CTNND1,MYL12B,PRSS8,LGALS3,FXYD3,PSMD7,ASAH1,RACGAP1,RAB6A,NCKAP1,FBLN1,ANO1,CORO1B,MYO5C,BMP2,VASP,TIMP1,FRAS1,AHCY,TMEM8A,NTN1,WNT3A,ALDH3A2,CKAP4,PSMA5,ABCC1,PCBP3,SCRIB,MAPKAPK2,EPN3,PVRL2,COL13A1,CSF1,PRPS2,FAM213A,LTBP2,ATP1B3,SEMA3A,UGP2,P3H2,XYLT1,CTDSPL,PCBP1,C1orf116,SDF4,PDGFA,EFR3A,PLCG2,VAT1,GLB1L2,NOTCH3,OAS3,MINPP1,LMAN1,GM2A,SULF2,CTH,CPD,TIMP2,TCEB2,FIGNL1,S100A4,ACO1,MYL12A,C3orf33,DAG1,RTN4RL1,PTPRJ,IDE,ATP1A1,PAFAH1B3,MMP17,PSMD3,ADAMTS14,CHMP4B,EFNA5,ANXA9,RPL22,LTA4H,ST3GAL1,CMTM4,CTDSP1,MAN2B2,COL9A3,PACSIN2,ADGRG1,CD63,TAB3,RUSC2,CTSB,BLVRB,GNAL,CDCA8,GDF15,CRABP2,VPS26A,DNAJB9,NRP2,SIRPA,MTRNR2L1,CD109,LYPD6,FAM63A,IL17RA,ALDH7A1,ATP2B1,GCNT1,FAH,P2RX4,FBLN5,RHOA,PSMB4,IFITM3,GUSB,CRB3,PLAUR,COL7A1,CAPNS1,GGH,FXR2,RNPEP,SCRN2,PRDX4,DDX23,FUCA1,DDAH1,SERPINA1,FAT4,TWSG1,SCG2,FGF18,TMC5,PGRMC1,PKD2,SH3BGRL2,ACADM,ICOSLG,NDFIP1,TBC1D4,SAT2,LAMP1,GAA,TXN,HSPG2,ATP8A1,FAM129B,PPFIBP2,PDGFRL,PSME1,NANS,PLXNA1,VASH1,NCS1,CTGF,SERINC2,AOX1,TACSTD2,MTMR11,TFG,ZBTB18,LAMP2,LOC81691,SNTB2,HSPA12A,MGAM,GALNT7,AURKB,SLC25A5,TP53I3,RAB2B,KDSR,AREG,PTER,PPP2R4,BMP1,SERPINI1,RTN3,HLA-E,KIF23,NDUFA4,SLC1A3,NOTCH2,PRRG4,CALR,DOPEY2,ITGA3,CYR61,SNX18,LYPD3,VASN,RPL39,SORL1,CYSRT1,CD70,OSTF1,CTSD,RIMS2,GFPT1,SPATA20,QSOX1,KLK5,PRSS23,MFI2,CALM1,ANO6,PIP4K2C,PYGL,NPC2,CYFIP2,PKM,JADE2,ANTXR1,STX3,FRMD4B,FAS,PRKAG2,ISM1,MATN2,APPL2,KLK7,EFNA1,EHD1,SLC2A4,TRIP10,S100A11,ST14,NDRG1,IQGAP1,BROX,FTH1,KCTD12,CD274,AIFM2,DDR1,GNB2,TMPRSS4,ART5,EPS8L2,CD46,APLP2,NOV,RALB,DAB2IP,EPHB4,LGMN,TSPAN1,SULT2B1,FLOT2,NAGA,TMBIM1,GPX4,SEMA3B,MYO5B,LYRM1,CLSTN1,UTRN,ATP1B1,AKR1E2,H2AFV,ALCAM,SP4,ZMPSTE24,CMTM7,EPHA10,ACYP1,STK26,PPP1CB,NRG1,RAB29,B4GALT3,MAMDC2,WASF3,PLSCR4,PCOLCE,IGFBP6,HAPLN3,EPS8,GPR180,SEPP1,SPR,EFNB1,FGF19,LGALS3BP,HLA-A,COX7A2,WWP2,MGAT1,PTEN,FUT8,FJX1,CD9,SLC44A2,TAGLN2,ERBB3,PDGFC,B3GNT2,SHMT1,CASK,ALDH2,FURIN,PARP4,C1GALT1C1,C2orf69,UBAC1,YES1,AIF1L,ARSK,GPLD1,CRTC2,NUCB1,TIMP3,CTNS,ACADSB,FGFR2,PRDX3,ABCB1,ERAP1,SERPINB5,ARSB,RGMA,LTBP1,ST13,CRYM,ABHD17B,HEBP1,PLAC1,MPP5,TAF6L,ERP29,ECI1,EPCAM,RAB15,METTL7A,TSPAN6,DPYSL2,DLG1,CAPG,AKR1B1,RP2,MYH14,CTTN,IL1RAP,NLRP4,OLFML2A,SOD1,ASXL1,LAP3,ITCH,ARHGDIB,TCN2,SEC14L2,MDK,ZNF114,GPRC5B,HPSE,UEVLD,DHRS13,TRIM45,CAB39,GLA,CPPED1,CAPN1,PCSK5,GRN,LASP1,FAM213B,SERPINE2,ASL,CALM3,PM20D2,ADAMTSL4,QSOX2,SPP1,CES2,CA2,PFKL,FAM20C,OCRL,COL6A1,PRKCI,HLA-C,SLC12A2,SNED1,VWA1,NUBP1,C3orf58,EGFR,MUM1L1,GNAS,INSR,PLPP3,CGREF1,SH3BP4,NXPH4,CTSA,PITPNA,EGFL7,KIF12,SHROOM2,COL16A1,APOL2,PROM2,ZSWIM5,IL15,PSME2,HDAC11,SOD2,COL18A1,MRAS,EXT2,SVBP,ARTN,SMO,GOT1,ECE1,PDIA6,LOXL1,F2R,HSPA2,CHP1,GCA,IGSF8,GLO1,ERBB2IP,CD40,BHLHB9,SECTM1,CANT1,SPTBN5,LIFR,ANXA3,ENO2,TSPAN15,SERPINB9,COL4A5,NOTUM,ITGA2B,TMEM63A,IRF2BPL,IL17RB,MLPH,TAF1B,A4GALT,BMP7,GALNS,ACTA2,H2AFY,HSPA13,MYO5A,SYPL1,PGM1,RAB3B,WNT10B,NDRG3,LEPR,ENDOD1,CTSL,HLA-B,GAREM2,CD8A,RND3,DHRS2,PRCP,CTSV,SPINT2,RAP2C,UBE2D2,UACA,GLB1,ATP6V1C1,PLOD3,NXPE3,LRRC57,CD33 |
| 2.005e-02 | -3.91 | negative regulation of NF-kappaB transcription factor activity | biological process | GO:0032088 | 68 | 17 | 16441 | 2455 |
SIRT1,DAP,ITCH,PSMD10,ERBB2IP,IRAK1,SIVA1,BMP7,NFKBIA,NOD2,NLRC5,TRIM21,ARRB1,DAB2IP,GFI1,CHP1,CYP1B1 |
| 2.005e-02 | -3.91 | positive regulation of production of molecular mediator of immune response | biological process | GO:0002702 | 68 | 17 | 16441 | 2455 |
KLK5,HLA-E,TRAF2,VAMP3,WHSC1,CD40,HLA-A,BCL10,GPRC5B,STAT6,NR4A3,NOD2,KLK7,FZD5,MAP3K7,F2RL1,MSH6 |
| 2.006e-02 | -3.91 | RhoGAP | smart domains | SM00324 | 64 | 17 | 9131 | 1455 |
ARHGAP11A,ARAP3,ARAP2,RALBP1,PIK3R1,RACGAP1,ABR,SYDE2,ARHGAP35,ARHGAP24,ARHGAP42,SH3BP1,OCRL,FAM13B,ARAP1,ARHGAP4,STARD13 |
| 2.007e-02 | -3.91 | MULLIGHAN_MLL_SIGNATURE_2_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_DN | 270 | 52 | 17758 | 2588 |
CD99,AGRN,TRIM24,SERPINE2,MCTP2,CTDSPL,PDIA5,ARFGEF1,C5orf30,EGR3,BAIAP3,DHRS3,KTN1,TSPAN7,SLC9A3R2,LGALS3BP,MYO5C,BTG3,RPS6KA2,LRRN2,MCF2L,DAPK1,TNPO2,SORL1,SCN2A,LOXL1,MAST4,EEF1D,FAH,ARAP2,ASXL1,STAT4,LYRM1,PRKCQ,ATP1B1,YES1,LHFPL2,SESN1,MDK,ENDOD1,PGF,JAK1,AREG,H1F0,GNPTAB,SIPA1L1,ABCB1,CLMN,EGFL7,ITGAV,ICOSLG,ISOC1 |
| 2.008e-02 | -3.91 | GRUETZMANN_PANCREATIC_CANCER_DN | MSigDB lists | GRUETZMANN_PANCREATIC_CANCER_DN | 199 | 40 | 17758 | 2588 |
LAMP1,PAX6,NF2,PEX6,DAP,ETV5,PDIA5,PBX3,NUCB2,WWP2,SRPX,P4HB,SHC3,IL6ST,GPC3,SRP54,SGK1,LMAN1,LOXL1,PPIF,SEC61B,LGALS8,DSTN,ACO1,PRKAR2B,F12,MEST,SLC25A5,NFIB,CYB5A,PRDX4,BTG1,NUCB1,ONECUT1,INSR,HTT,MAOA,ACADM,TOB1,DMPK |
| 2.009e-02 | -3.91 | maintenance of protein location | biological process | GO:0045185 | 89 | 21 | 16441 | 2455 |
SUN1,SUN2,LTBP1,PINK1,NFKBIE,AKT1,SYNE3,THRA,SYNE2,PDIA3,KDELR3,PSMD10,EZR,DAG1,NFKBIA,SORL1,SUN3,PKD2,TLN2,MDFI,KDELR1 |
| 2.009e-02 | -3.91 | CTSC (cathepsin C) | protein interactions | 1075 | 11 | 5 | 16036 | 2547 |
CTSL,FBXO6,CTSC,CD81,CAPN1 |
| 2.009e-02 | -3.91 | RNASET2 (ribonuclease T2) | protein interactions | 8635 | 11 | 5 | 16036 | 2547 |
FBXO6,PRDX3,TRAF2,FBXO2,PDIA5 |
| 2.009e-02 | -3.91 | CLEC18A (C-type lectin domain family 18, member A) | protein interactions | 348174 | 11 | 5 | 16036 | 2547 |
SCRIB,ADAMTSL4,PPP2R2D,DNAJC3,DNAJB9 |
| 2.009e-02 | -3.91 | HIST1H2BN (histone cluster 1, H2bn) | protein interactions | 8341 | 11 | 5 | 16036 | 2547 |
IGSF8,CD81,SPRTN,ICAM1,ASB9 |
| 2.009e-02 | -3.91 | GCC2 (GRIP and coiled-coil domain containing 2) | protein interactions | 9648 | 11 | 5 | 16036 | 2547 |
GCC2,ZRANB1,SPC25,ARL1,RAD23A |
| 2.010e-02 | -3.91 | STROIDFINGER | prints domains | PR00047 | 46 | 12 | 4759 | 661 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 2.011e-02 | -3.91 | PAS | interpro domains | IPR000014 | 34 | 10 | 18293 | 2672 |
AHRR,NCOA3,EPAS1,PASK,ARNT2,PER3,AHR,ARNT,NCOA2,PER2 |
| 2.012e-02 | -3.91 | ubiquitin-like protein binding | molecular function | GO:0032182 | 111 | 25 | 16491 | 2452 |
UFD1L,FAF2,DNAJB2,SPRTN,SHARPIN,C6orf106,MVB12B,HDAC6,TP53INP2,VCP,PER2,OPTN,RAD23A,BCL10,TOP2A,IDE,DCUN1D1,OTUB2,CRY2,ZRANB1,SIMC1,HSPB1,CBX4,RNF169,USP16 |
| 2.013e-02 | -3.91 | ubiquitin-like protein ligase binding | molecular function | GO:0044389 | 259 | 51 | 16491 | 2452 |
SCN5A,FAF2,PINK1,GRIK2,TRAF2,JKAMP,CUL4B,TP53,CUL1,UBE2Z,ERBB2,TRIB2,HDAC6,PRKACA,SNX9,MAP1LC3B,FZD6,CALR,RB1,UBE2T,RALB,UBE2J1,TMBIM6,PDE4D,DLG3,BAG4,TCEB2,FZD4,UBE2A,PRKAR2B,CD40,SLC25A5,EGFR,VCP,GABARAPL1,BCL10,JAK1,DNM1L,WFS1,NFKBIA,TRIOBP,PIAS2,ARRB1,AURKA,YOD1,FZD5,PER3,TRAF5,UBE2C,TMEM173,PRKAR1A |
| 2.019e-02 | -3.90 | PID_RAC1_PATHWAY | MSigDB lists | PID_RAC1_PATHWAY | 54 | 14 | 17758 | 2588 |
NOXA1,CTNNB1,CDH1,IQGAP1,LIMK1,PAK2,MAP3K11,RACGAP1,NCKAP1,IQGAP3,CYFIP2,ARPC2,BCAR1,PLCB2 |
| 2.019e-02 | -3.90 | CTCTAGA,MIR-526C,MIR-518F,MIR-526A | MSigDB lists | CTCTAGA,MIR-526C,MIR-518F,MIR-526A | 54 | 14 | 17758 | 2588 |
SS18,MLEC,KLF12,TBC1D8B,ZKSCAN2,CD9,ZC3H12B,PIK3CD,SRSF5,FHL1,EGLN3,ANTXR1,FLT3,CBX4 |
| 2.019e-02 | -3.90 | FIRESTEIN_PROLIFERATION | MSigDB lists | FIRESTEIN_PROLIFERATION | 170 | 35 | 17758 | 2588 |
PACSIN2,INPP5D,EPHA4,PRKAA1,ETNK1,GRK6,PKN1,MERTK,PICK1,CDK14,WWP2,PIK3AP1,CDKL5,PRKG1,CKS1B,AK3,EPHB4,ERBB3,ADCK3,PIK3R1,PPARA,ROR1,CD40,PRKRA,TXK,FYN,CCNB3,C17orf51,AXL,LIMK1,PDXK,C17orf75,NRBP1,ZC3HC1,DMPK |
| 2.020e-02 | -3.90 | protein tyrosine kinase binding | molecular function | GO:1990782 | 48 | 13 | 16491 | 2452 |
DOCK4,PLCG1,FNTA,PCNA,ELMO2,SHC3,PIK3R1,LRP4,TP53,NRG1,TOB1,ARHGEF16,SOCS5 |
| 2.025e-02 | -3.90 | GGATTA_V$PITX2_Q2 | MSigDB lists | GGATTA_V$PITX2_Q2 | 552 | 98 | 17758 | 2588 |
LTBP1,ACVR1,ARMCX3,TRIP10,FAM198B,FAM101B,GNB2,KTN1,SYTL2,KCTD15,RNF220,HSF2,CDKL5,MITF,SLC44A1,SRR,DUSP10,SCN3A,SMARCA2,CXXC5,FZD4,UTRN,RGAG1,C12orf65,TNS1,SP4,IRX3,PGF,PIAS3,RTN4RL1,BFSP1,RBM47,MAP2,SIPA1L1,TDRD7,KLF5,SP6,ARF6,LIFR,NR3C2,RTN3,NDST3,ARNT,CBX4,ANXA11,TM2D2,ARAP3,CPEB4,MCTP2,SOX9,NOTCH2,DHRS3,HPCAL4,ANO1,DUSP5,SRPX2,C16orf74,ADD3,ADORA1,ITGA3,PPP1R10,ZNRF2,LLGL2,CTSC,FLRT3,WNT3A,CNPY3,GAD1,SPRY2,RBMS2,IGSF3,EPB41L5,MOB4,TGIF1,PDGFC,PLEKHA6,HMGN5,TCF7,RAB3IP,ANKRD29,PRX,PITX2,BTG1,H1F0,ACVRL1,CCDC6,FIBCD1,ITPR1,MAP3K5,SEMA3A,SHOX2,OCLN,RPS6KA3,FOXA1,JARID2,GOLGB1,PHC1,DMPK |
| 2.027e-02 | -3.90 | fn3 | pfam domains | PF00041 | 137 | 30 | 16629 | 2504 |
PTPRU,EPHA4,VWA1,COL7A1,IL27RA,EPHA1,FNDC3A,MYOM1,MERTK,COL12A1,NEO1,TRIM9,PTPRF,EPHA10,PTPRJ,INSR,IGSF9,IL6ST,AXL,ANKFN1,IL31RA,MYLK,SORL1,OSMR,EPHB4,NCAM1,L1CAM,LIFR,SNED1,IGDCC4 |
| 2.032e-02 | -3.90 | ENO2 (enolase 2 (gamma, neuronal)) | protein interactions | 2026 | 84 | 21 | 16036 | 2547 |
SIGIRR,SOD1,TXN,AKT1,CUL4B,HABP4,ASB9,EZR,CUL1,EFHD2,PLS3,RCN1,CALR,PTEN,AKR1B1,TAGLN2,UBE2C,ANXA11,CTH,TUBA4A,GPX4 |
| 2.033e-02 | -3.90 | SAM_PNT | smart domains | SM00251 | 11 | 5 | 9131 | 1455 |
ETS2,ETV7,ETS1,ELF5,ELF3 |
| 2.034e-02 | -3.90 | extrinsic component of cytoplasmic side of plasma membrane | cellular component | GO:0031234 | 96 | 22 | 17570 | 2579 |
TNK1,FARP1,IQGAP1,GNAL,RACGAP1,TEC,YES1,SNX9,GNA11,TXK,GNAS,RGS9,FYN,JAK1,SNX18,CDK16,ARRB1,JAK3,TIAM1,SYK,S100A6,ESYT2 |
| 2.037e-02 | -3.89 | myxoid | COSMIC cancer mutations | myxoid | 16 | 6 | 17775 | 2585 |
GNAS,RB1,SS18,TFG,IDH1,PTEN |
| 2.037e-02 | -3.89 | urinary_tract-carcinoma | COSMIC cancer mutations | urinary_tract-carcinoma | 16 | 6 | 17775 | 2585 |
TSC1,CTNNB1,AKT1,PTEN,PIK3CA,TP53 |
| 2.041e-02 | -3.89 | REGULATION_OF_ORGANELLE_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | REGULATION_OF_ORGANELLE_ORGANIZATION_AND_BIOGENESIS | 39 | 11 | 17758 | 2588 |
ARHGEF10L,TSC1,MID1IP1,NF2,CAPG,ARAP1,SORBS3,PIF1,ARF6,CCDC88A,RASA1 |
| 2.041e-02 | -3.89 | REACTOME_IL1_SIGNALING | MSigDB lists | REACTOME_IL1_SIGNALING | 39 | 11 | 17758 | 2588 |
MAP3K3,IL1R1,IRAK1,RIPK2,TAB3,PELI2,NOD2,CUL1,PELI3,MAP3K7,IL1RAP |
| 2.041e-02 | -3.89 | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN | MSigDB lists | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN | 39 | 11 | 17758 | 2588 |
CCNE2,BTG3,PCNA,PAPSS2,CELSR2,PRSS23,MICB,NAB2,RAB31,NCAPG2,SMC4 |
| 2.041e-02 | -3.89 | KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_DN | MSigDB lists | KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_DN | 39 | 11 | 17758 | 2588 |
RALGPS2,PVRL2,RND3,NR1D2,LPGAT1,SUZ12,XIAP,KDELR3,MGST2,EGR3,UNC5B |
| 2.041e-02 | -3.89 | BIOCARTA_P38MAPK_PATHWAY | MSigDB lists | BIOCARTA_P38MAPK_PATHWAY | 39 | 11 | 17758 | 2588 |
MAPKAPK2,PLA2G4A,TRAF2,RAPGEF2,STAT1,MAP3K9,TGFBR1,MAP3K7,MAP3K5,ELK1,HSPB1 |
| 2.042e-02 | -3.89 | WTTGKCTG_UNKNOWN | MSigDB lists | WTTGKCTG_UNKNOWN | 490 | 88 | 17758 | 2588 |
LTBP1,ACVR1,REPS2,SLC25A13,MORF4L2,NANS,SEPT4,BAHD1,APC2,PHF1,SLC25A35,CYP26A1,PCNA,CDH1,CDKL5,PRICKLE3,LMAN2L,TMEM143,ANKRD12,CDKN1B,DAB2IP,DIXDC1,RP2,NOTCH3,DLG3,FAR1,MYT1,TIAM1,MAP3K3,BAG4,CXXC5,CAPN6,COQ10B,SERTAD3,C12orf65,SLC11A2,ATP1B1,MRPS36,CDC25C,CAMK2N2,SLC25A4,HOXA9,NKD1,TLE1,CTNND1,KLF11,PPP2R5D,NR2C2,RMND5A,IER5L,SORT1,SLC41A1,PDIA3,TRIB2,CRABP2,C3orf18,TEAD3,TMCC3,RND1,HDAC9,FOXP2,FRY,CDK16,ANKS1B,FRAS1,CALD1,SELK,NTN1,NCAM1,MDFI,C9orf9,DPYSL5,HES1,PHF20L1,MLEC,PIK3R1,NFIB,PRX,ARAP1,FAM83D,ETAA1,NDE1,UBE2C,IFIH1,SEMA3A,KLF7,PHC1,TLL2 |
| 2.046e-02 | -3.89 | purine nucleoside diphosphate metabolic process | biological process | GO:0009135 | 63 | 16 | 16441 | 2455 |
PGM1,CASK,ENO2,PFKFB2,MPP1,OGDHL,AK4,PKM,NUDT16,PFKL,MPP2,DLG1,DHTKD1,AK3,DLG3,PPP2R5D |
| 2.046e-02 | -3.89 | purine ribonucleoside diphosphate metabolic process | biological process | GO:0009179 | 63 | 16 | 16441 | 2455 |
PGM1,CASK,ENO2,PFKFB2,MPP1,OGDHL,AK4,PKM,NUDT16,PFKL,MPP2,DLG1,DHTKD1,AK3,DLG3,PPP2R5D |
| 2.050e-02 | -3.89 | MORF_AP2M1 | MSigDB lists | MORF_AP2M1 | 211 | 42 | 17758 | 2588 |
LASP1,TCF25,PSMD7,MORF4L2,GNB2,BCAP31,CALR,DNPEP,P4HB,TMBIM6,RPN2,PPP1CA,EEF1D,TMED2,KDELR1,GPX4,PIGC,SOD1,SEC61B,PSMB4,TCEB2,VAMP3,MYL12A,PSMA4,VCP,RHEB,GNAS,DDOST,SETD3,PPP2R4,MAP3K11,MDH1,SSNA1,PIEZO1,ARPC2,PLOD3,PSMC1,CTBP1,MYL12B,SRSF9,CAPN1,PRKAR1A |
| 2.050e-02 | -3.89 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | MSigDB lists | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | 49 | 13 | 17758 | 2588 |
PSMD1,PSMB4,TCEB2,PSME2,PSMD3,PSMC2,PSMD7,PSMD10,PSME1,PSMC1,APOBEC3G,PSMA4,PSMA5 |
| 2.050e-02 | -3.89 | HALMOS_CEBPA_TARGETS_UP | MSigDB lists | HALMOS_CEBPA_TARGETS_UP | 49 | 13 | 17758 | 2588 |
BMP2,IL1R1,BTG1,PTGS2,PLCG1,UAP1,ETS2,EPHA4,KLF5,SERPINI1,BMP2K,CKAP4,FAS |
| 2.050e-02 | -3.89 | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | MSigDB lists | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | 49 | 13 | 17758 | 2588 |
AMOTL2,CDKN2C,QSOX1,PCOLCE,FBLN5,CTGF,PLOD2,IL6ST,LTBP2,ATP1B1,SEPP1,DDR1,IRF1 |
| 2.050e-02 | -3.89 | MORI_IMMATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_IMMATURE_B_LYMPHOCYTE_UP | 49 | 13 | 17758 | 2588 |
GRN,GNS,TMEM50B,ATP6V0B,BTG1,TAPBP,SEMA4D,CAPG,CD40,RGS14,CAPN1,JARID2,CD83 |
| 2.050e-02 | -3.89 | REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | MSigDB lists | REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | 49 | 13 | 17758 | 2588 |
PSMD1,PSMB4,PSME2,PSMD3,CDC20,PSMC2,PSMD7,PSMD10,CUL1,PSME1,PSMC1,PSMA4,PSMA5 |
| 2.053e-02 | -3.89 | external side of plasma membrane | cellular component | GO:0009897 | 233 | 46 | 17570 | 2579 |
LAMP1,BCAM,SLC2A4,LGALS3,SERPINE2,CTSB,ITGA6,SELL,P2RX7,CD274,PLPPR4,SDC1,FLT3,ANO1,TMC1,ITGA2B,ICAM1,CALR,TGFBR3,SCNN1A,ITGA3,P4HB,CD22,IL6ST,CD9,TNFRSF18,ECE1,C10orf54,NCAM1,CLCN3,SPA17,CR2,CD40,ALCAM,CD83,FAS,CD8A,RTN4RL1,CTSV,NRG1,EFNA5,ITGAV,ABCA1,L1CAM,CD33,ABCG1 |
| 2.055e-02 | -3.88 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_DN | 176 | 36 | 17758 | 2588 |
NUDT6,COL9A3,GPR107,TMX4,FAM134A,UBE2Q1,EGR3,NOTCH2,ISYNA1,FLII,SPP1,IRAK1,ADRBK1,CYR61,SIVA1,FABP6,FOSB,SRR,PRKCI,CCDC82,KLF9,NFE2L3,SPATA20,STAU2,PLEKHO1,PDE5A,SCRIB,STK17B,FNTA,KLF12,PTER,LRIG1,SLC4A3,RHOBTB2,PKD2,APBA2 |
| 2.056e-02 | -3.88 | regulation of oxidative stress-induced cell death | biological process | GO:1903201 | 43 | 12 | 16441 | 2455 |
SIRT1,SOD1,TXN,PINK1,AKT1,P4HB,STK26,SOD2,NR4A3,HDAC6,MAPK7,HSPB1 |
| 2.057e-02 | -3.88 | SULFURIC_ESTER_HYDROLASE_ACTIVITY | MSigDB lists | SULFURIC_ESTER_HYDROLASE_ACTIVITY | 16 | 6 | 17758 | 2588 |
GNS,ARSB,ARSG,ARSK,GALNS,SULF2 |
| 2.057e-02 | -3.88 | MODULE_495 | MSigDB lists | MODULE_495 | 16 | 6 | 17758 | 2588 |
CCDC68,PPP4R4,RCBTB2,PVRL2,CKAP2,IL1RAP |
| 2.057e-02 | -3.88 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | MSigDB lists | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | 16 | 6 | 17758 | 2588 |
NOTCH2,NOTCH3,RAB6A,LFNG,TMED2,FURIN |
| 2.057e-02 | -3.88 | LEE_LIVER_CANCER_HEPATOBLAST | MSigDB lists | LEE_LIVER_CANCER_HEPATOBLAST | 16 | 6 | 17758 | 2588 |
EZR,PTGS2,TIMP1,FOS,NR4A1,PLAUR |
| 2.057e-02 | -3.88 | GALACTOSYLTRANSFERASE_ACTIVITY | MSigDB lists | GALACTOSYLTRANSFERASE_ACTIVITY | 16 | 6 | 17758 | 2588 |
B3GALNT1,UGT8,B4GALT3,B4GALT4,A4GALT,ITGA2B |
| 2.057e-02 | -3.88 | MACLACHLAN_BRCA1_TARGETS_DN | MSigDB lists | MACLACHLAN_BRCA1_TARGETS_DN | 16 | 6 | 17758 | 2588 |
ZYX,CCNB1,COL16A1,CD9,SEMA3B,BAX |
| 2.057e-02 | -3.88 | XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | MSigDB lists | XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | 16 | 6 | 17758 | 2588 |
LAMP2,HDAC1,GSTP1,ITGA6,NMI,STAT1 |
| 2.057e-02 | -3.88 | MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION_AND_BIOGENESIS | 16 | 6 | 17758 | 2588 |
CNTROB,NDE1,KIF11,UXT,SAC3D1,CKAP5 |
| 2.057e-02 | -3.88 | PID_INTEGRIN5_PATHWAY | MSigDB lists | PID_INTEGRIN5_PATHWAY | 16 | 6 | 17758 | 2588 |
TGFBR1,ITGAV,ITGB8,CYR61,SDC1,PLAUR |
| 2.057e-02 | -3.88 | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_DN | MSigDB lists | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_DN | 16 | 6 | 17758 | 2588 |
AIM1L,FARP1,HSPG2,CPE,PTGES,CDA |
| 2.060e-02 | -3.88 | MARTIN_INTERACT_WITH_HDAC | MSigDB lists | MARTIN_INTERACT_WITH_HDAC | 44 | 12 | 17758 | 2588 |
RUNX2,PPP1R12A,GATA2,NFKBIA,PPP2R4,BCL6,KPNA2,RUNX3,CBX5,NR2C1,CTBP1,EDNRA |
| 2.060e-02 | -3.88 | MODULE_284 | MSigDB lists | MODULE_284 | 44 | 12 | 17758 | 2588 |
ZWINT,IGF1R,OSBPL3,FAM3C,NR4A3,EPHA1,PLXNA1,SLC1A3,PHLDA1,RAP1GAP,RPS6KA3,TCN2 |
| 2.060e-02 | -3.88 | TSENG_ADIPOGENIC_POTENTIAL_DN | MSigDB lists | TSENG_ADIPOGENIC_POTENTIAL_DN | 44 | 12 | 17758 | 2588 |
IL1R1,CDKN2C,B3GALNT1,ENPP1,POPDC3,CAPN6,TSPAN6,IL6ST,COL6A1,CST3,PHKA2,SESN1 |
| 2.060e-02 | -3.88 | MCDOWELL_ACUTE_LUNG_INJURY_UP | MSigDB lists | MCDOWELL_ACUTE_LUNG_INJURY_UP | 44 | 12 | 17758 | 2588 |
KLHL2,LTBP1,SPP1,CYR61,NR4A1,ZFP36,NFKBIA,LITAF,OSMR,FOS,PTGES,DUSP1 |
| 2.063e-02 | -3.88 | RAF1 (Raf-1 proto-oncogene, serine/threonine kinase) | protein interactions | 5894 | 162 | 36 | 16036 | 2547 |
TSC22D3,PRKAA1,XIAP,MRAS,BCL2L1,PRKACA,GNB2,SH3KBP1,RB1,PAK2,BCL6,PRKG1,SGK1,MAPK7,PHKA2,SPRY2,AKT1,NR3C1,PBK,CALM1,ERBB2IP,ILK,PKM,RANBP9,RHEB,VCP,EGFR,FYN,INSR,JAK1,STK26,UBE2D2,SPRY4,MAP3K5,DMPK,PRKAR1A |
| 2.065e-02 | -3.88 | GSE6269_E_COLI_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_E_COLI_VS_STREP_PNEUMO_INF_PBMC_DN | 153 | 32 | 17758 | 2588 |
ANXA3,ASL,PDIA5,FLOT1,PRRG4,SDF4,APLP2,P4HB,GALNS,CAPG,TMBIM6,TACSTD2,CTSD,TMEM8A,FLOT2,SPRY2,CKAP4,MYO5A,CYP1B1,CDA,PYGL,MGAM,GGH,RNF19B,CYP4F3,STX3,MAN2A2,IL1R1,TWSG1,CLMN,PLXND1,RTN3 |
| 2.066e-02 | -3.88 | GnRH signaling pathway | KEGG pathways | hsa04912 | 91 | 22 | 6908 | 1076 |
MAP3K3,PLA2G4A,CALM1,CALM3,PLD2,ITPR2,ITPR3,ELK1,PRKACA,GNA11,EGFR,GNAS,CALM2,ITPR1,MAPK13,MAPK11,PLD1,CACNA1D,MAPK7,PLCB2,CAMK2G,MAPK12 |
| 2.066e-02 | -3.88 | GnRH signaling pathway | KEGG pathways | ko04912 | 91 | 22 | 6908 | 1076 |
MAP3K3,PLA2G4A,CALM1,CALM3,PLD2,ITPR2,ITPR3,ELK1,PRKACA,GNA11,EGFR,GNAS,CALM2,ITPR1,MAPK13,MAPK11,PLD1,CACNA1D,MAPK7,PLCB2,CAMK2G,MAPK12 |
| 2.068e-02 | -3.88 | epoxide hydrolase activity | molecular function | GO:0004301 | 8 | 4 | 16491 | 2452 |
LTA4H,RNPEP,EPHX4,EPHX1 |
| 2.068e-02 | -3.88 | protein phosphatase activator activity | molecular function | GO:0072542 | 8 | 4 | 16491 | 2452 |
CALM3,CALM2,CALM1,PPP2R4 |
| 2.068e-02 | -3.88 | Arp2/3 complex binding | molecular function | GO:0071933 | 8 | 4 | 16491 | 2452 |
ARPC2,SNX9,PICK1,CORO1B |
| 2.068e-02 | -3.88 | cAMP-dependent protein kinase inhibitor activity | molecular function | GO:0004862 | 8 | 4 | 16491 | 2452 |
PRKAR2B,PRKAG2,PKIA,PRKAR1A |
| 2.068e-02 | -3.88 | AP-2 adaptor complex binding | molecular function | GO:0035612 | 8 | 4 | 16491 | 2452 |
ARRB1,LDLRAP1,RAB38,FCHO1 |
| 2.068e-02 | -3.88 | very long-chain fatty acid-CoA ligase activity | molecular function | GO:0031957 | 8 | 4 | 16491 | 2452 |
SLC27A1,ACSL4,SLC27A6,SLC27A3 |
| 2.073e-02 | -3.88 | RGS | interpro domains | IPR016137 | 39 | 11 | 18293 | 2672 |
SNX13,RGS9,RGS12,ADRBK1,ARHGEF11,RGS3,RGS20,RGS5,GRK6,RGS14,ADRBK2 |
| 2.075e-02 | -3.88 | chaperone binding | molecular function | GO:0051087 | 79 | 19 | 16491 | 2452 |
HES1,BAG4,SOD1,ST13,DNAJC3,DNAJB2,AMFR,TP53,ERP29,CALR,HLA-B,TSC1,DNAJC10,ATP1A1,GNB5,CTSC,TBCD,BAX,CDKN1B |
| 2.076e-02 | -3.87 | regulation of microtubule polymerization or depolymerization | biological process | GO:0031110 | 58 | 15 | 16441 | 2455 |
GAS2L1,PSRC1,MID1IP1,CKAP2,TUBGCP6,TBCD,AURKA,CDKN1B,STMN3,SLAIN2,AURKB,CCNB1,HDAC6,SKA1,APC2 |
| 2.076e-02 | -3.87 | protein homotetramerization | biological process | GO:0051289 | 58 | 15 | 16441 | 2455 |
CRTC2,ACACB,KCNJ12,VASP,ALDH5A1,IDE,SHMT1,DHPS,DNM1L,PFKL,SRR,CDA,SOD2,USP16,CTH |
| 2.076e-02 | -3.87 | post-embryonic development | biological process | GO:0009791 | 100 | 23 | 16441 | 2455 |
EMX1,INPPL1,TMTC3,RC3H2,ACO1,GATA3,GABRG2,TGFBR1,PYGO1,SEPP1,SGPL1,MECOM,TP73,GNAS,FGFR2,IMPAD1,ITPR1,BAX,NR4A2,ERCC2,FZD5,MYT1,TIPARP |
| 2.079e-02 | -3.87 | Ald_DH_CS_CYS | interpro domains | IPR016160 | 16 | 6 | 18293 | 2672 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 2.079e-02 | -3.87 | dDENN_dom | interpro domains | IPR005112 | 16 | 6 | 18293 | 2672 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 2.079e-02 | -3.87 | Ald_DH_CS_GLU | interpro domains | IPR029510 | 16 | 6 | 18293 | 2672 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH3A2,ALDH1A3 |
| 2.079e-02 | -3.87 | Guanylate_kinase_CS | interpro domains | IPR020590 | 16 | 6 | 18293 | 2672 |
MPP5,CASK,DLG3,MPP1,DLG1,MPP2 |
| 2.079e-02 | -3.87 | uDENN_dom | interpro domains | IPR005113 | 16 | 6 | 18293 | 2672 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 2.079e-02 | -3.87 | DENN_dom | interpro domains | IPR001194 | 16 | 6 | 18293 | 2672 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 2.083e-02 | -3.87 | negative regulation of transcription from RNA polymerase II promoter | biological process | GO:0000122 | 730 | 129 | 16441 | 2455 |
TXN,CRYM,TSC22D3,SUDS3,LMCD1,GATA3,TP73,CTNNB1,ZFP36,MITF,FOSB,DLG1,IRF2,CRY2,ZBTB18,PLK1,THRB,SMARCA2,KCNIP3,CXXC5,ASXL1,UXT,CBX6,TFAP2C,EZR,AURKB,AHRR,KLF12,PRDM5,HDAC1,KLF11,E2F8,CDKN1C,SOX9,SORBS3,BMP2,CALR,RB1,GATA2,BHLHE41,FNIP1,RFX5,DLX4,ETV7,MDFI,SALL4,FHL2,WHSC1,NFIB,ETS2,SEMA4D,NR4A2,EFNA1,PER3,RARG,CTBP1,ELK4,TCF25,FOXM1,SUZ12,THRA,TP53,WDTC1,OSR2,MXD1,PER2,SAP130,CCND1,SP100,DACT1,SMO,BCL6,TWIST1,DAB2IP,NOTCH3,NFKB2,NR2C1,SIRT1,DRAP1,NFIX,ARHGAP35,HSF4,MYPOP,RBL1,STAT6,WFS1,WWTR1,PEX2,STAT1,OVOL1,TLE1,IRF7,KLF5,CBX7,CBX4,GLIS3,PSMD10,AES,ZNF219,WWP2,HDAC9,IRF2BPL,CTNNBIP1,E2F7,TFAP2A,TMBIM6,H2AFY,KANK2,HEXIM2,CITED2,GFI1,NCOA2,NFE2L3,TGIF1,HES1,WNT10B,PPARA,RUNX3,PITX2,CNOT2,FGFR2,TBX18,NR4A3,E2F1,OSR1,SHOX2,AHR,PKIA,JARID2 |
| 2.087e-02 | -3.87 | neuron death | biological process | GO:0070997 | 48 | 13 | 16441 | 2455 |
CASP3,RB1,GRIK2,HTT,TP53,SLC25A27,BAX,KLK6,ERBB3,BCL2L1,SCN2A,DPYSL4,FAS |
| 2.087e-02 | -3.87 | protein autoubiquitination | biological process | GO:0051865 | 48 | 13 | 16441 | 2455 |
DDB2,RNF220,UBE2T,AMFR,TRAF2,RNF11,UBE2A,UBE2D2,TRIM21,RAG1,TRIM68,RNF146,WWP2 |
| 2.087e-02 | -3.87 | IDH1 (isocitrate dehydrogenase 1 (NADP+)) | protein interactions | 3417 | 50 | 14 | 16036 | 2547 |
RCN1,SLC2A4,DAZAP1,PEX5,OXCT1,DCK,RANBP1,CAB39,EFHD2,GOT1,ETHE1,LTA4H,PCBP1,ARF4 |
| 2.087e-02 | -3.87 | STK11 (serine/threonine kinase 11) | protein interactions | 6794 | 50 | 14 | 16036 | 2547 |
MOB4,SIRT1,PRKAA2,MARK1,PTEN,PRKAA1,UBE2D2,TP53,CAB39,STRADB,KIF23,PRKACA,ETV4,RPS6KA3 |
| 2.087e-02 | -3.87 | IRS2 (insulin receptor substrate 2) | protein interactions | 8660 | 50 | 14 | 16036 | 2547 |
PTPRF,SIRT1,PLCG1,INSR,IGF1R,JAK1,PIK3R1,PIK3CA,PIK3CD,BCL2L1,JAK3,DVL2,EGFR,SOCS3 |
| 2.088e-02 | -3.87 | GSE22886_NAIVE_BCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_DC_UP | 182 | 37 | 17758 | 2588 |
KLF2,IL15,TSC22D3,SCD5,EPHA4,SERPINB9,MCTP2,SELL,TESK2,TRMT2B,DDR1,FAM46C,C11orf95,FZD6,PAK6,CD22,FRAS1,MTMR10,ITM2C,NCOA2,DUSP1,POU6F1,CXorf57,CR2,CYFIP2,MEST,PRIM1,ENDOD1,GALNT3,BTG1,PHLPP2,PIK3C2B,SPRY4,RPL22,NR3C2,PHC1,FAM134B |
| 2.088e-02 | -3.87 | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | 182 | 37 | 17758 | 2588 |
RMND5A,ELK4,LZTFL1,ARMCX3,FAM160B1,TMEM55B,EFHD2,TNFSF9,KREMEN1,TMCC3,KIF5B,KIAA1107,DAPK1,STEAP2,TNFRSF12A,ALDH7A1,C8orf58,DLG3,TIAM1,TTLL1,ATG4D,POU6F1,SSH3,CASK,CELSR2,KLK6,KCTD2,RASA1,GIGYF1,SERTAD2,ETS2,DCK,RAP2C,GLCCI1,CXorf56,FBXW5,RGMA |
| 2.090e-02 | -3.87 | UDP-galactosyltransferase activity | molecular function | GO:0035250 | 20 | 7 | 16491 | 2452 |
B3GALT6,B3GALNT1,UGT8,B4GALT4,PLOD3,B4GALT3,A4GALT |
| 2.090e-02 | -3.87 | peptidase activator activity involved in apoptotic process | molecular function | GO:0016505 | 20 | 7 | 16491 | 2452 |
CDKN1B,CARD8,NKX3-1,BCL2L13,CTSC,NGFRAP1,EBAG9 |
| 2.090e-02 | -3.87 | histone kinase activity | molecular function | GO:0035173 | 20 | 7 | 16491 | 2452 |
PRKAA2,AURKA,AURKB,PKN1,CCNB1,CDK1,PRKAA1 |
| 2.090e-02 | -3.87 | FEVR_CTNNB1_TARGETS_DN | MSigDB lists | FEVR_CTNNB1_TARGETS_DN | 534 | 95 | 17758 | 2588 |
PLA2G4A,CCNE2,PAPSS2,FOXM1,CRYM,NUF2,APPBP2,CCND1,WEE1,PCNA,RGS12,CCNA2,NUP210,CTNNB1,TM9SF2,SLC46A1,AKR1B1,KIF22,EPHB4,SMYD5,TIAM1,FIGNL1,SH3BGRL,CDC20,AURKB,SLC25A5,CDC25C,CDK1,SGPP1,NFIX,PRIM1,ANKRD10,CDCA4,IDE,SECTM1,LRIG1,PPP1CB,KPNA2,ARF6,FGD1,SCOC,SERPINE2,CKAP2,CENPI,SDC4,SOX9,KIF23,CBLL1,RACGAP1,TGFBR1,NOTCH2,LBR,PPP2R3A,KIF5B,TOP2A,ADD3,CA2,PTEN,KCNN4,FRAS1,PRC1,MSH2,H2AFY,BUB1,USP1,KNTC1,SLC12A2,RPGR,EEF1D,MSH6,SHMT1,HMGN5,KIF20A,ADCK3,PIK3R1,MBNL3,BORA,SKA1,C4orf27,EGFR,G2E3,PRDX4,RPL12,DCK,PRPS2,MATN2,E2F1,ETAA1,CENPE,CBX5,CCNB2,MELK,CSRP2,CYBRD1,RAD21 |
| 2.091e-02 | -3.87 | regulation of cellular response to oxidative stress | biological process | GO:1900407 | 53 | 14 | 16441 | 2455 |
SIRT1,SOD1,TXN,PINK1,FBLN5,AKT1,P4HB,STK26,BMP7,SOD2,NR4A3,HDAC6,MAPK7,HSPB1 |
| 2.095e-02 | -3.87 | LIPID_BINDING | MSigDB lists | LIPID_BINDING | 86 | 20 | 17758 | 2588 |
ARAP2,MCTP1,ARAP3,ALDH6A1,MCTP2,SYP,SYTL4,NPC2,ZFYVE16,WDFY1,PLA2G15,PGRMC1,BAX,ARAP1,PRKCI,ANXA9,APOL2,RASGRP1,ACOT7,CCDC88A |
| 2.095e-02 | -3.87 | POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | MSigDB lists | POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | 86 | 20 | 17758 | 2588 |
MAP3K3,CXXC5,RHOA,RIPK2,LITAF,CD40,SLC20A1,BCL10,PLK2,TSPAN6,SECTM1,ZDHHC13,NOD2,SLC44A2,CANT1,TFG,NDFIP1,TRAF5,F2R,EEF1D |
| 2.095e-02 | -3.87 | TAKAO_RESPONSE_TO_UVB_RADIATION_UP | MSigDB lists | TAKAO_RESPONSE_TO_UVB_RADIATION_UP | 86 | 20 | 17758 | 2588 |
GRN,CD99,SOD1,TXN,S100A4,SAT1,NDUFA4,FTH1,COX6C,RNPEP,ITGA2B,COX7A2,ATP6V0B,PRDX3,SPINT2,DBI,MANF,EEF1D,ACOT7,GPX4 |
| 2.095e-02 | -3.87 | Apoptotic cleavage of cellular proteins | REACTOME pathways | R-HSA-111465 | 38 | 11 | 8202 | 1235 |
CASP3,FNTA,CASP7,ADD1,CTNNB1,CDH1,STK26,PRKCQ,BCAP31,LMNA,OCLN |
| 2.095e-02 | -3.87 | Collagen degradation | REACTOME pathways | R-HSA-1442490 | 38 | 11 | 8202 | 1235 |
CTSL,MMP15,COL9A3,ADAM17,COL13A1,CTSB,FURIN,COL18A1,CTSD,COL16A1,COL12A1 |
| 2.096e-02 | -3.86 | V$NKX62_Q2 | MSigDB lists | V$NKX62_Q2 | 229 | 45 | 17758 | 2588 |
FARP1,CHCHD7,TSC22D3,PRKAA1,FLOT1,IRX4,RAB6A,SLC20A1,ETS1,FGF19,TSPAN7,LTBP3,SCML1,IER3,CDKN2C,AIM1L,IRAK1,ARTN,CALD1,FLRT3,MITF,TMEM143,CLDN4,TWIST1,DIXDC1,WNT3A,BTBD3,MYT1,ETV4,SMARCA2,SERTAD4,CYFIP2,ITPR3,NFIX,SLC44A3,RTN4RL1,SMTNL2,ITGA7,STK38,PELI2,ABCB1,PRIMA1,UNC5B,SHOX2,IFIH1 |
| 2.099e-02 | -3.86 | PITPNB (phosphatidylinositol transfer protein, beta) | protein interactions | 23760 | 23 | 8 | 16036 | 2547 |
SOD1,ALDH6A1,LMO4,PGM2L1,GOT1,OAT,PCBP1,HSPB1 |
| 2.099e-02 | -3.86 | CSN2 (casein beta) | protein interactions | 1447 | 23 | 8 | 16036 | 2547 |
PLK1,CUL4B,NEK2,FHL2,ARRB1,AURKA,CUL1,CDK1 |
| 2.099e-02 | -3.86 | APAF1 (apoptotic peptidase activating factor 1) | protein interactions | 317 | 23 | 8 | 16036 | 2547 |
CASP3,CASP9,XIAP,PPP1CA,BCL2L1,APIP,CASP4,FAS |
| 2.099e-02 | -3.86 | STT3B (STT3B, subunit of the oligosaccharyltransferase complex (catalytic)) | protein interactions | 201595 | 23 | 8 | 16036 | 2547 |
UNC93B1,DDOST,CORO1C,TP53,RPN2,FBXO6,TMEM173,ABCC1 |
| 2.099e-02 | -3.86 | ACOT13 (acyl-CoA thioesterase 13) | protein interactions | 55856 | 23 | 8 | 16036 | 2547 |
LMAN2L,PPP2R4,KLC2,RAB31,ECI2,KPNA2,PCTP,PDIA6 |
| 2.099e-02 | -3.86 | STK39 (serine threonine kinase 39) | protein interactions | 27347 | 23 | 8 | 16036 | 2547 |
SPP1,MBP,PCNA,PRKCQ,STK39,NUBP1,SLC12A2,EHD1 |
| 2.099e-02 | -3.86 | autophagic cell death | biological process | GO:0048102 | 8 | 4 | 16441 | 2455 |
LAMP1,CDKN1B,CDKN2D,CTSV |
| 2.099e-02 | -3.86 | metanephric nephron tubule morphogenesis | biological process | GO:0072282 | 8 | 4 | 16441 | 2455 |
HES1,SOX8,LGR4,SOX9 |
| 2.099e-02 | -3.86 | response to water deprivation | biological process | GO:0009414 | 8 | 4 | 16441 | 2455 |
AKR1B1,LRP11,TFAP2A,CD9 |
| 2.099e-02 | -3.86 | intracellular sterol transport | biological process | GO:0032366 | 8 | 4 | 16441 | 2455 |
NPC2,LDLRAP1,ABCA1,ABCG1 |
| 2.099e-02 | -3.86 | sebaceous gland development | biological process | GO:0048733 | 8 | 4 | 16441 | 2455 |
TFAP2C,FA2H,CBX7,ZDHHC21 |
| 2.099e-02 | -3.86 | negative regulation of phospholipid metabolic process | biological process | GO:1903726 | 8 | 4 | 16441 | 2455 |
PDGFA,SLC27A1,DAB2IP,PDGFB |
| 2.099e-02 | -3.86 | regulation of gamma-delta T cell activation | biological process | GO:0046643 | 8 | 4 | 16441 | 2455 |
EGR3,SYK,SOX13,NOD2 |
| 2.099e-02 | -3.86 | sulfate assimilation | biological process | GO:0000103 | 8 | 4 | 16441 | 2455 |
TXN,PAPSS2,SULT2B1,PAPSS1 |
| 2.099e-02 | -3.86 | galactose catabolic process | biological process | GO:0019388 | 8 | 4 | 16441 | 2455 |
PGM2L1,GLB1,GALK1,PGM1 |
| 2.099e-02 | -3.86 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c | biological process | GO:0008635 | 8 | 4 | 16441 | 2455 |
CASP3,CASP7,CASP9,BAX |
| 2.099e-02 | -3.86 | heparin biosynthetic process | biological process | GO:0030210 | 8 | 4 | 16441 | 2455 |
NDST3,XYLT2,GLCE,CSGALNACT1 |
| 2.099e-02 | -3.86 | glucose import | biological process | GO:0046323 | 8 | 4 | 16441 | 2455 |
TSC1,SORT1,SLC2A4,DRD1 |
| 2.099e-02 | -3.86 | negative regulation of cAMP-dependent protein kinase activity | biological process | GO:2000480 | 8 | 4 | 16441 | 2455 |
SIRT1,PRKAR2B,PKIA,PRKAR1A |
| 2.099e-02 | -3.86 | regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | GO:0045091 | 8 | 4 | 16441 | 2455 |
TOP2A,APOBEC3H,APOBEC3D,APOBEC3G |
| 2.099e-02 | -3.86 | regulation of antimicrobial humoral response | biological process | GO:0002759 | 8 | 4 | 16441 | 2455 |
PPP2R3C,KLK7,KLK5,NOD2 |
| 2.099e-02 | -3.86 | protein localization to endosome | biological process | GO:0036010 | 8 | 4 | 16441 | 2455 |
PACSIN2,ACAP2,ARF6,TMEM30A |
| 2.100e-02 | -3.86 | - | gene3d domains | 3.40.309.10 | 19 | 7 | 9988 | 1574 |
ALDH7A1,ALDH3B1,ALDH2,ALDH5A1,ALDH6A1,ALDH3A2,ALDH1A3 |
| 2.100e-02 | -3.86 | - | gene3d domains | 3.40.605.10 | 19 | 7 | 9988 | 1574 |
ALDH7A1,ALDH3B1,ALDH2,ALDH5A1,ALDH6A1,ALDH3A2,ALDH1A3 |
| 2.102e-02 | -3.86 | ATGCTGG,MIR-338 | MSigDB lists | ATGCTGG,MIR-338 | 108 | 24 | 17758 | 2588 |
MAP3K3,ADAM17,ACVR1,RUNX2,GGA1,AMFR,BCL9,UBE2Q1,MORF4L2,TANC1,SEPT4,UNC45B,ETS1,ZDHHC21,ARHGEF10L,CCND1,DUOX1,VASP,FRY,PPP4R1,SP6,ARNT,ATP2B1,ESYT2 |
| 2.107e-02 | -3.86 | clear_cell | COSMIC cancer mutations | clear_cell | 12 | 5 | 17775 | 2585 |
NF2,AKT1,IDH1,PTEN,PIK3CA |
| 2.107e-02 | -3.86 | trachea | COSMIC cancer mutations | trachea | 12 | 5 | 17775 | 2585 |
ERBB2,PTEN,EGFR,PIK3CA,TP53 |
| 2.107e-02 | -3.86 | blastoma | COSMIC cancer mutations | blastoma | 12 | 5 | 17775 | 2585 |
ERBB2,CTNNB1,EGFR,PIK3CA,TP53 |
| 2.107e-02 | -3.86 | pituitary-adenoma-FSH-LH | COSMIC cancer mutations | pituitary-adenoma-FSH-LH | 12 | 5 | 17775 | 2585 |
GNAS,RB1,CTNNB1,RET,PIK3CA |
| 2.107e-02 | -3.86 | extraadrenal | COSMIC cancer mutations | extraadrenal | 12 | 5 | 17775 | 2585 |
GNAS,CDKN2C,PTEN,RET,PRKAR1A |
| 2.107e-02 | -3.86 | FSH-LH | COSMIC cancer mutations | FSH-LH | 12 | 5 | 17775 | 2585 |
GNAS,RB1,CTNNB1,RET,PIK3CA |
| 2.107e-02 | -3.86 | central_nervous_system-cerebellum-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-cerebellum-other-rosette-forming_glioneuronal_tumour | 12 | 5 | 17775 | 2585 |
GNAS,AKT1,IDH1,RET,PIK3CA |
| 2.117e-02 | -3.86 | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_DN | 188 | 38 | 17758 | 2588 |
ACVR1,GOLIM4,IL15RA,IBTK,IL15,PSME2,BCL2L1,BMP2K,ABCD4,PDGFA,RASSF8,CTGF,ZFP36,N4BP3,TLN2,NFKB2,ETHE1,SMYD5,CTDSP2,IL1RAP,PSMA5,FAM69A,UFD1L,RHOA,SLC39A8,STAT4,DCHS1,BLVRA,STEAP1,SPAG1,OPTN,PTGS2,PPM1H,INPP4B,ARSB,SLC31A2,PTGES,IRF1 |
| 2.117e-02 | -3.86 | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDM_UP | 188 | 38 | 17758 | 2588 |
TTC8,RECQL,CCDC109B,CHCHD7,LFNG,DNAJB2,AES,KCTD12,NDUFA4,NANS,GALM,NUCB2,LMNA,NEO1,NUP210,HSF2,FAM102A,TRAM1,NAGA,GM2A,KDELR1,SMARCA2,PTPN18,UXT,TEF,LPGAT1,HMG20B,TNS1,OSBPL2,ACYP1,FAM3C,CDCA5,KPNA2,RPL22,PPP2R5D,ACOT7,FAM45A,CTDSP1 |
| 2.117e-02 | -3.86 | GSE17721_LPS_VS_POLYIC_1H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_1H_BMDM_DN | 188 | 38 | 17758 | 2588 |
ELK4,SIGIRR,SORT1,SELL,CRABP2,ARHGEF40,MNS1,KIAA1161,ADD3,ENTPD4,CA2,SLC16A6,PCYOX1,CKAP4,HP1BP3,KDELR1,ABCC1,REC8,SMARCA2,HPS3,TRIM8,CAPN6,DIAPH2,SNAPC2,SNTB1,TRIM7,ATP13A2,IRX3,NUDT16,DNAJC10,SPINT2,CANT1,ARRDC1,ALG2,LRRK1,MAD2L1BP,ANXA11,USP43 |
| 2.117e-02 | -3.86 | GSE3982_EOSINOPHIL_VS_MAST_CELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAST_CELL_DN | 188 | 38 | 17758 | 2588 |
GRN,SORBS1,GNPDA1,VANGL1,CAST,GMPR,CCDC68,COX6C,SEPP1,DHRS3,ABCD4,PCNA,PSMD1,LMAN2L,AKR1B1,VAT1,RPN2,APIP,ERCC2,MANF,EGLN3,TRAM1,MAST4,CRTAP,CYP1B1,WBP5,DCAF6,RC3H2,PDHX,OPTN,MFAP3L,WDR11,MAP2,IARS2,CDK18,MDH1,CBX5,E2F8 |
| 2.117e-02 | -3.86 | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN | 188 | 38 | 17758 | 2588 |
WASF3,HECA,PACSIN2,HAL,WDTC1,OSGIN2,FLOT1,TESK2,ETS1,SYTL2,B4GALNT1,PAK6,SH3D21,KCTD15,FUT2,SLC16A6,POF1B,SORL1,TFG,PTPRE,CKAP4,GPR161,RHOA,TEP1,EMP3,KCTD20,ATP8B3,DOCK5,RNF19B,RASGRP2,OSBPL2,HLF,HPSE,NEIL3,CPPED1,JARID2,TLL2,EHD1 |
| 2.117e-02 | -3.86 | GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP | 188 | 38 | 17758 | 2588 |
MAN2B2,SLC25A24,PARP12,IL15,INPP5D,ATP8A1,DGKA,SMARCAL1,NKRF,MAP1LC3B,TIPRL,EXT2,DENND2D,SLC25A36,ZFYVE16,RNF220,SP100,CD22,AIM1,CAPG,FBXL14,SNX10,ATP2B1,MCCC2,MOB4,RIPK2,LPGAT1,PIK3R1,PLEKHO1,RUNX3,DNAJB14,KDM3A,NDRG3,ARHGAP24,ALDH5A1,RYK,PPP1CB,RPS6KA3 |
| 2.117e-02 | -3.86 | GSE17721_LPS_VS_POLYIC_6H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDM_UP | 188 | 38 | 17758 | 2588 |
ARMCX3,HJURP,DHPS,FAM129B,STRN4,PSMD7,PBX3,SLC7A2,PLA2G16,OAT,TNFSF9,ZFYVE16,RAC2,NOV,VASP,ADRBK1,XYLT2,PHTF1,RAB20,TAGLN2,SGCB,ETV4,IL1RAP,ABCC1,CKS2,PPIF,HMGN5,VPS4B,CALCRL,FAM133B,ALCAM,STK17B,LCP1,VCP,SH3BGRL2,STK39,PPP2R3C,GLA |
| 2.122e-02 | -3.85 | cellular response to topologically incorrect protein | biological process | GO:0035967 | 122 | 27 | 16441 | 2455 |
GFPT1,UFD1L,SEC61B,HSP90B1,ADD1,SEC61G,AMFR,DNAJC3,ERO1A,PDIA5,KDELR3,DNAJB11,HDAC6,VCP,DNAJB9,LMNA,CCND1,CALR,WIPI1,WFS1,BAX,DAB2IP,YOD1,MYDGF,PDIA6,CTDSP2,CTH |
| 2.125e-02 | -3.85 | MCBRYAN_TERMINAL_END_BUD_UP | MSigDB lists | MCBRYAN_TERMINAL_END_BUD_UP | 12 | 5 | 17758 | 2588 |
TNFRSF12A,TNS1,IGFBP2,SDC1,CDK1 |
| 2.125e-02 | -3.85 | POS_RESPONSE_TO_HISTAMINE_UP | MSigDB lists | POS_RESPONSE_TO_HISTAMINE_UP | 12 | 5 | 17758 | 2588 |
H2AFY,HMG20B,FBLN5,UPF3B,FRYL |
| 2.125e-02 | -3.85 | RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 12 | 5 | 17758 | 2588 |
FARP1,ARHGEF3,ARHGEF11,TIAM1,FARP2 |
| 2.125e-02 | -3.85 | INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHATASE_ACTIVITY | MSigDB lists | INOSITOL_OR_PHOSPHATIDYLINOSITOL_PHOSPHATASE_ACTIVITY | 12 | 5 | 17758 | 2588 |
INPP5E,PTEN,OCRL,INPP5D,INPP4B |
| 2.125e-02 | -3.85 | SA_REG_CASCADE_OF_CYCLIN_EXPR | MSigDB lists | SA_REG_CASCADE_OF_CYCLIN_EXPR | 12 | 5 | 17758 | 2588 |
CDKN1B,CCND1,CCNE2,CCNA2,E2F1 |
| 2.125e-02 | -3.85 | CDC42_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | CDC42_PROTEIN_SIGNAL_TRANSDUCTION | 12 | 5 | 17758 | 2588 |
FGD6,ABCA1,RALBP1,ARAP1,FGD1 |
| 2.125e-02 | -3.85 | NEBEN_AML_WITH_FLT3_OR_NRAS_DN | MSigDB lists | NEBEN_AML_WITH_FLT3_OR_NRAS_DN | 12 | 5 | 17758 | 2588 |
KIF23,WEE1,RAC2,PKMYT1,CYP2J2 |
| 2.125e-02 | -3.85 | MALIK_REPRESSED_BY_ESTROGEN | MSigDB lists | MALIK_REPRESSED_BY_ESTROGEN | 12 | 5 | 17758 | 2588 |
CDH3,CLDN4,BMP7,NDRG1,BIK |
| 2.125e-02 | -3.85 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | MSigDB lists | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | 12 | 5 | 17758 | 2588 |
CALM2,CALM3,AKT1,SPR,CALM1 |
| 2.125e-02 | -3.85 | MAP_KINASE_ACTIVITY | MSigDB lists | MAP_KINASE_ACTIVITY | 12 | 5 | 17758 | 2588 |
MAPK11,MAPK13,MAPK4,MAPK7,MAPK12 |
| 2.130e-02 | -3.85 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | 307 | 58 | 17758 | 2588 |
CCNE2,CASP3,CDK17,FAF2,PRKAA1,TAP1,PDCL,EGR3,DNAJB9,WEE1,ZFX,BTG3,CTGF,SP100,CYR61,ZFP36,BCL6,PLK4,TRPC1,TRIM21,IFIT1,PDE4D,TIPARP,DUSP1,MOB4,LOC81691,TAF5,CD55,ZWINT,PLSCR1,NR3C1,IFITM3,ITCH,FHL2,IFIT3,STK17B,STX3,GABARAPL1,BCL10,DCTN6,CASP7,H1F0,RAB11FIP2,RND3,CCDC6,NR1D2,DHRS2,NFKBIA,NMI,STAT1,TDRD7,NR4A2,IRF7,ZBTB6,GEM,SHOX2,IFI6,SRSF9 |
| 2.133e-02 | -3.85 | Peptidase_C50 | interpro domains | IPR005314 | 2 | 2 | 18293 | 2672 |
CFAP46,ESPL1 |
| 2.133e-02 | -3.85 | CKAP2_fam | interpro domains | IPR026165 | 2 | 2 | 18293 | 2672 |
CKAP2L,CKAP2 |
| 2.133e-02 | -3.85 | Glyco_trans_11 | interpro domains | IPR002516 | 2 | 2 | 18293 | 2672 |
FUT2,FUT1 |
| 2.133e-02 | -3.85 | Serpin_B9/Maspin | interpro domains | IPR000240 | 2 | 2 | 18293 | 2672 |
SERPINB5,SERPINB9 |
| 2.133e-02 | -3.85 | CO_DH_flav_C | interpro domains | IPR005107 | 2 | 2 | 18293 | 2672 |
AOX1,XDH |
| 2.133e-02 | -3.85 | Prominin | interpro domains | IPR008795 | 2 | 2 | 18293 | 2672 |
PROM1,PROM2 |
| 2.133e-02 | -3.85 | RB_C | interpro domains | IPR015030 | 2 | 2 | 18293 | 2672 |
RB1,RBL1 |
| 2.133e-02 | -3.85 | Nonsense_mediated_decay_UPF3 | interpro domains | IPR005120 | 2 | 2 | 18293 | 2672 |
UPF3B,UPF3A |
| 2.133e-02 | -3.85 | Interferon_reg_fac-1/2 | interpro domains | IPR017431 | 2 | 2 | 18293 | 2672 |
IRF2,IRF1 |
| 2.133e-02 | -3.85 | PLipase_D_fam | interpro domains | IPR015679 | 2 | 2 | 18293 | 2672 |
PLD2,PLD1 |
| 2.133e-02 | -3.85 | PDGF_N | interpro domains | IPR006782 | 2 | 2 | 18293 | 2672 |
PDGFA,PDGFB |
| 2.133e-02 | -3.85 | Glyco_hydro_27/36_CS | interpro domains | IPR000111 | 2 | 2 | 18293 | 2672 |
GLA,NAGA |
| 2.133e-02 | -3.85 | Glyco_hydro_27 | interpro domains | IPR002241 | 2 | 2 | 18293 | 2672 |
GLA,NAGA |
| 2.133e-02 | -3.85 | Sulphate_adenylyltransferase | interpro domains | IPR002650 | 2 | 2 | 18293 | 2672 |
PAPSS2,PAPSS1 |
| 2.133e-02 | -3.85 | Syntaphilin/Syntabulin | interpro domains | IPR028197 | 2 | 2 | 18293 | 2672 |
SYBU,SNPH |
| 2.133e-02 | -3.85 | PRibTrfase_C | interpro domains | IPR013583 | 2 | 2 | 18293 | 2672 |
MCTP1,MCTP2 |
| 2.133e-02 | -3.85 | DUF4757 | interpro domains | IPR031865 | 2 | 2 | 18293 | 2672 |
LMO7,LIMCH1 |
| 2.133e-02 | -3.85 | TF_GATA-2/3 | interpro domains | IPR016374 | 2 | 2 | 18293 | 2672 |
GATA3,GATA2 |
| 2.133e-02 | -3.85 | DUF3350 | interpro domains | IPR021785 | 2 | 2 | 18293 | 2672 |
TBC1D4,TBC1D1 |
| 2.133e-02 | -3.85 | Acid_ceramidase-like | interpro domains | IPR016699 | 2 | 2 | 18293 | 2672 |
ASAH1,NAAA |
| 2.133e-02 | -3.85 | Acid_ceramidase_N | interpro domains | IPR029130 | 2 | 2 | 18293 | 2672 |
ASAH1,NAAA |
| 2.133e-02 | -3.85 | PLipase_D1/D2 | interpro domains | IPR016555 | 2 | 2 | 18293 | 2672 |
PLD2,PLD1 |
| 2.133e-02 | -3.85 | Flotillin_fam | interpro domains | IPR027705 | 2 | 2 | 18293 | 2672 |
FLOT2,FLOT1 |
| 2.133e-02 | -3.85 | Gprotein_alpha_S | interpro domains | IPR000367 | 2 | 2 | 18293 | 2672 |
GNAS,GNAL |
| 2.133e-02 | -3.85 | Mopterin_DH_FAD-bd | interpro domains | IPR002346 | 2 | 2 | 18293 | 2672 |
AOX1,XDH |
| 2.133e-02 | -3.85 | Ald_Oxase/Xan_DH_a/b | interpro domains | IPR000674 | 2 | 2 | 18293 | 2672 |
AOX1,XDH |
| 2.133e-02 | -3.85 | COQ10_START | interpro domains | IPR005031 | 2 | 2 | 18293 | 2672 |
COQ10A,COQ10B |
| 2.133e-02 | -3.85 | PLC-gamma | interpro domains | IPR016279 | 2 | 2 | 18293 | 2672 |
PLCG1,PLCG2 |
| 2.133e-02 | -3.85 | Cell_morpho_N | interpro domains | IPR025614 | 2 | 2 | 18293 | 2672 |
FRY,FRYL |
| 2.133e-02 | -3.85 | CBAH/NAAA_C | interpro domains | IPR029132 | 2 | 2 | 18293 | 2672 |
ASAH1,NAAA |
| 2.133e-02 | -3.85 | Ald_Oxase/xanthine_DH | interpro domains | IPR016208 | 2 | 2 | 18293 | 2672 |
AOX1,XDH |
| 2.133e-02 | -3.85 | DUF4927 | interpro domains | IPR032565 | 2 | 2 | 18293 | 2672 |
NCOA3,NCOA2 |
| 2.133e-02 | -3.85 | Isochorismatase-like | interpro domains | IPR000868 | 2 | 2 | 18293 | 2672 |
ISOC2,ISOC1 |
| 2.133e-02 | -3.85 | Cyclin-dep_kinase_reg-sub | interpro domains | IPR000789 | 2 | 2 | 18293 | 2672 |
CKS1B,CKS2 |
| 2.133e-02 | -3.85 | Kremen | interpro domains | IPR017076 | 2 | 2 | 18293 | 2672 |
KREMEN2,KREMEN1 |
| 2.133e-02 | -3.85 | CCDC74_C | interpro domains | IPR029422 | 2 | 2 | 18293 | 2672 |
CCDC74B,CCDC74A |
| 2.133e-02 | -3.85 | PC_trans | interpro domains | IPR000374 | 2 | 2 | 18293 | 2672 |
CDS2,CDS1 |
| 2.133e-02 | -3.85 | APS_kinase | interpro domains | IPR002891 | 2 | 2 | 18293 | 2672 |
PAPSS2,PAPSS1 |
| 2.133e-02 | -3.85 | Male_sterile_NAD-bd | interpro domains | IPR013120 | 2 | 2 | 18293 | 2672 |
FAR2,FAR1 |
| 2.133e-02 | -3.85 | OKL38_fam | interpro domains | IPR029731 | 2 | 2 | 18293 | 2672 |
OSGIN1,OSGIN2 |
| 2.133e-02 | -3.85 | DUF3480 | interpro domains | IPR022557 | 2 | 2 | 18293 | 2672 |
ZFYVE16,ZFYVE9 |
| 2.133e-02 | -3.85 | Cell_Morphogen_C | interpro domains | IPR025481 | 2 | 2 | 18293 | 2672 |
FRY,FRYL |
| 2.133e-02 | -3.85 | AK3/Ak4_mitochondrial | interpro domains | IPR028586 | 2 | 2 | 18293 | 2672 |
AK4,AK3 |
| 2.133e-02 | -3.85 | ATP-Sase_PUA-like_dom | interpro domains | IPR025980 | 2 | 2 | 18293 | 2672 |
PAPSS2,PAPSS1 |
| 2.133e-02 | -3.85 | FAR | interpro domains | IPR026055 | 2 | 2 | 18293 | 2672 |
FAR2,FAR1 |
| 2.133e-02 | -3.85 | LEDGF | interpro domains | IPR021567 | 2 | 2 | 18293 | 2672 |
HDGFRP2,PSIP1 |
| 2.133e-02 | -3.85 | XTBD | interpro domains | IPR021859 | 2 | 2 | 18293 | 2672 |
CDKN2AIP,CDKN2AIPNL |
| 2.133e-02 | -3.85 | AldOxase/xan_DH_Mopterin-bd | interpro domains | IPR008274 | 2 | 2 | 18293 | 2672 |
AOX1,XDH |
| 2.133e-02 | -3.85 | Sulfurylase_cat_dom | interpro domains | IPR024951 | 2 | 2 | 18293 | 2672 |
PAPSS2,PAPSS1 |
| 2.133e-02 | -3.85 | MOR2-PAG1_mid | interpro domains | IPR029473 | 2 | 2 | 18293 | 2672 |
FRY,FRYL |
| 2.133e-02 | -3.85 | XylT | interpro domains | IPR024448 | 2 | 2 | 18293 | 2672 |
XYLT2,XYLT1 |
| 2.133e-02 | -3.85 | IL17R_fnIII_D1 | interpro domains | IPR032356 | 2 | 2 | 18293 | 2672 |
IL17RB,IL17RA |
| 2.133e-02 | -3.85 | MDFI/MDFIC | interpro domains | IPR026134 | 2 | 2 | 18293 | 2672 |
MDFIC,MDFI |
| 2.133e-02 | -3.85 | DBB_domain | interpro domains | IPR017893 | 2 | 2 | 18293 | 2672 |
BANK1,PIK3AP1 |
| 2.133e-02 | -3.85 | Glyco_trans_13 | interpro domains | IPR004139 | 2 | 2 | 18293 | 2672 |
POMGNT1,MGAT1 |
| 2.133e-02 | -3.85 | Glyco_hydro_35_CS | interpro domains | IPR019801 | 2 | 2 | 18293 | 2672 |
GLB1,GLB1L2 |
| 2.133e-02 | -3.85 | Myrip/Melanophilin | interpro domains | IPR006788 | 2 | 2 | 18293 | 2672 |
MLPH,MYRIP |
| 2.133e-02 | -3.85 | AMPK_C | interpro domains | IPR032270 | 2 | 2 | 18293 | 2672 |
PRKAA2,PRKAA1 |
| 2.133e-02 | -3.85 | CKAP2_C | interpro domains | IPR029197 | 2 | 2 | 18293 | 2672 |
CKAP2L,CKAP2 |
| 2.133e-02 | -3.85 | Transform_prot_C-ets | interpro domains | IPR016311 | 2 | 2 | 18293 | 2672 |
ETS2,ETS1 |
| 2.133e-02 | -3.85 | Flotillin_C | interpro domains | IPR031905 | 2 | 2 | 18293 | 2672 |
FLOT2,FLOT1 |
| 2.133e-02 | -3.85 | PC_Trfase_euk | interpro domains | IPR016720 | 2 | 2 | 18293 | 2672 |
CDS2,CDS1 |
| 2.133e-02 | -3.85 | Sec2_N | interpro domains | IPR009449 | 2 | 2 | 18293 | 2672 |
RAB3IP,RAB3IL1 |
| 2.133e-02 | -3.85 | 2Fe-2S-bd | interpro domains | IPR002888 | 2 | 2 | 18293 | 2672 |
AOX1,XDH |
| 2.133e-02 | -3.85 | Nuclear_rcpt_coactivator | interpro domains | IPR017426 | 2 | 2 | 18293 | 2672 |
NCOA3,NCOA2 |
| 2.133e-02 | -3.85 | E3_ub_ligase_SMURF1 | interpro domains | IPR024928 | 2 | 2 | 18293 | 2672 |
WWP1,WWP2 |
| 2.136e-02 | -3.85 | establishment of mitotic spindle orientation | biological process | GO:0000132 | 20 | 7 | 16441 | 2455 |
CENPA,GPSM2,NDE1,SPDL1,HTT,SPRY2,NDC80 |
| 2.136e-02 | -3.85 | positive regulation of protein oligomerization | biological process | GO:0032461 | 20 | 7 | 16441 | 2455 |
IDE,BMF,SNX9,BIK,FAS,TP53,BAX |
| 2.138e-02 | -3.85 | Spitz | COSMIC cancer mutations | Spitz | 25 | 8 | 17775 | 2585 |
KIF5B,CEP89,TP53,GNA11,HLA-A,MYO5A,LMNA,EGFR |
| 2.139e-02 | -3.85 | Interferon Signaling | REACTOME pathways | R-HSA-913531 | 194 | 40 | 8202 | 1235 |
DDX58,TRIM2,TRIM5,HLA-E,HLA-F,HERC5,TRIM68,ICAM1,HLA-A,NUP210,SP100,TRIM3,TRIM21,IRF2,IFIT1,OAS3,HLA-C,NCAM1,TRIM62,NUP85,CAMK2G,MX1,TRIM8,IFITM3,USP18,TRIM35,IFIT3,SOCS3,HLA-B,PLCG1,JAK1,TRIM45,STAT1,IRF7,KPNA2,RNASEL,NUP37,NUP58,IFI6,IRF1 |
| 2.140e-02 | -3.84 | alpha-amino acid metabolic process | biological process | GO:1901605 | 253 | 50 | 16441 | 2455 |
PLA2G4A,GCLM,ALDH6A1,DHPS,GCAT,AASS,CRYM,HAL,ASL,MCCC1,SLC1A3,PLA2G16,OAT,SPR,P4HB,SLC46A1,SRR,CTPS1,SERINC2,ALDH7A1,AHCY,GOT1,HMGCL,APIP,EGLN3,ACAD8,GAD1,CRTAP,MCCC2,FAH,CTH,GFPT1,PRODH,SHMT1,PLSCR1,GCLC,ERO1A,CCBL2,GGH,ICMT,AMDHD1,PRDX4,DDAH1,ALDH5A1,ABHD12,HTT,P4HA2,SLC27A1,OCLN,EGLN1 |
| 2.141e-02 | -3.84 | Hirschsprung's disease(PMID:19196962) | GWAS genes | Hirschsprung's disease(PMID:19196962) | 2 | 2 | 2389 | 350 |
NRG1,RET |
| 2.141e-02 | -3.84 | Drug-induced liver injury (flucloxacillin)(PMID:19483685) | GWAS genes | Drug-induced liver injury (flucloxacillin)(PMID:19483685) | 2 | 2 | 2389 | 350 |
HCP5,MCTP2 |
| 2.141e-02 | -3.84 | Nephrolithiasis(PMID:22396660) | GWAS genes | Nephrolithiasis(PMID:22396660) | 2 | 2 | 2389 | 350 |
DGKH,RGS14 |
| 2.141e-02 | -3.84 | Colorectal cancer(PMID:19011631) | GWAS genes | Colorectal cancer(PMID:19011631) | 2 | 2 | 2389 | 350 |
RHPN2,CDH1 |
| 2.142e-02 | -3.84 | CATTTCA,MIR-203 | MSigDB lists | CATTTCA,MIR-203 | 277 | 53 | 17758 | 2588 |
PLEKHG3,CCNC,LASP1,PPP1R12A,CPEB4,NUAK1,XYLT1,C5orf30,CUL1,GPR180,NKRF,PLD2,ITPR2,EGR3,MORF4L2,DUSP5,KCTD9,AKIRIN1,FAM46A,RALB,SGK3,PRKG1,VAT1,LIMCH1,PDE4D,CITED2,SLC12A2,LAMP2,TAF5,TMTC2,NDRG3,STEAP1,SP4,SOX13,SOCS3,GABARAPL1,IRS2,DGCR2,ETS2,SLC4A4,KLF12,PRPS2,NR4A3,OVOL1,PPP1CB,CAB39,PCDH19,ZMIZ1,GLCCI1,AHR,RPS6KA3,NR2C2,EGLN1 |
| 2.144e-02 | -3.84 | GSE14308_TH2_VS_TH1_DN | MSigDB lists | GSE14308_TH2_VS_TH1_DN | 194 | 39 | 17758 | 2588 |
FAM92A1,DNAJC3,EPS8,RHBDL3,EPHX4,TP53,C5orf30,TXNDC9,MXD1,SS18,SESN3,OSBPL3,BCL6,ALDH7A1,C10orf54,CITED2,SUSD3,B3GNT2,SEPT6,EMP3,FAM133B,ARSK,GNA11,DGKH,PI4K2B,PLCG1,PLCH1,TMEM50B,NEIL1,JAK1,RBL1,ITGA7,ZDHHC20,ZNF704,ERAP1,IRF7,AKNA,ARF6,KLF7 |
| 2.144e-02 | -3.84 | GSE2826_XID_VS_BTK_KO_BCELL_DN | MSigDB lists | GSE2826_XID_VS_BTK_KO_BCELL_DN | 194 | 39 | 17758 | 2588 |
UGT8,EPAS1,TAP1,ETNK1,ABCG2,RACGAP1,F11R,EMP2,SIRPA,TOP2A,ITGA3,KCNN4,ICAM5,DDHD2,CKS1B,MXD3,MINPP1,ITM2C,IL10RB,PAQR7,THRB,CPD,PLAUR,ACO1,NUSAP1,BLVRA,BCL2L13,GABARAPL1,PRIM1,TXK,FECH,CASP7,COQ10A,CHMP4B,SERPINB6,ATP1B3,IFIH1,CCNB2,IRF1 |
| 2.144e-02 | -3.84 | GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDM_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDM_UP | 194 | 39 | 17758 | 2588 |
MRPS9,FAM89A,LZTFL1,IL15RA,TBC1D1,KLHL13,SLC41A1,NDRG1,ASL,F11R,CD274,ITPR2,CYP26A1,PDCD10,PHF7,ENPP5,SLC44A1,TAX1BP3,IL17RA,TSPAN13,OSTF1,CNGA1,SCARA3,FAH,VPS11,ELK3,TNIP1,PRICKLE1,FAS,MMP15,BTG1,SERTAD2,PRCP,DGAT2,SPAG7,GEM,TTC39C,L1CAM,PSMC1 |
| 2.144e-02 | -3.84 | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | 194 | 39 | 17758 | 2588 |
CASP3,FBLIM1,SLC25A24,TXN,CPEB4,HJURP,BLVRB,PKN1,KCNC4,SLC9A3R2,TEAD3,CYP26A1,CCDC92,VASP,RALB,MCF2L,PPP4R1,SGK3,SORL1,RAB20,TECR,TMEM8A,SNX10,TRAK2,HMMR,MPP1,LPGAT1,BORA,RANBP9,ARHGEF26,IRS2,DUOX1,CARHSP1,RBL1,WIPI1,AXL,NETO2,AGFG2,SRSF9 |
| 2.144e-02 | -3.84 | GSE17721_CTRL_VS_POLYIC_6H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_6H_BMDM_DN | 194 | 39 | 17758 | 2588 |
LZTFL1,ARHGEF3,ACVR1,GRHL2,CRYM,FRMD6,SOD2,CCNL1,CRABP2,KTN1,APPBP2,RAD23A,ELF3,IGSF9,FRYL,NECAB3,WBP4,TSPAN33,GCA,NUB1,C3orf52,PARP4,DBR1,CALCRL,EPHA1,STEAP1,MAPKAPK2,AP1AR,BFSP1,PPP2R5A,ETS2,CCDC6,TBX18,MRPS28,ICOSLG,ARF6,ISOC1,PTGES,EHD1 |
| 2.144e-02 | -3.84 | GSE3982_BASOPHIL_VS_TH1_DN | MSigDB lists | GSE3982_BASOPHIL_VS_TH1_DN | 194 | 39 | 17758 | 2588 |
CCNE2,MRC2,PPP1R2,NQO1,MRPS15,GCAT,CAST,PDIA5,SPSB1,SYTL2,SAC3D1,RANBP1,NEK2,MSH2,AKR1B1,TUBG1,DIXDC1,GLB1L2,PDE4D,APOBEC3G,MYO5A,CKS2,PPIF,DOCK4,CTNNAL1,TESK1,MICB,SNTB2,GGH,MRPS18A,ADRBK2,PLEKHG6,DDOST,NETO2,AURKA,STK39,HMGA1,NUP37,NRBP1 |
| 2.144e-02 | -3.84 | GSE20715_WT_VS_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_LUNG_UP | 194 | 39 | 17758 | 2588 |
DYNLRB1,PARP12,ST13,ARMCX3,EPAS1,FAM198B,MAP1LC3B,ANO1,CHST2,TMCC3,CALR,CDKN2C,PDGFA,BTG3,CTGF,NPNT,ARL1,RRBP1,RANBP1,CD9,GOT1,TACSTD2,ALDH3A2,SULF2,SYPL1,FBLN5,PIK3R1,FBXO8,NKAIN1,IFIT3,PTGS2,JAK1,GPRC5B,RND3,TWSG1,DCUN1D1,HSPB1,SERPINB1,PRKAR1A |
| 2.144e-02 | -3.84 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | 194 | 39 | 17758 | 2588 |
RECQL,PAPSS2,ATP9A,TRAF2,ARHGEF7,PPFIBP2,STRN4,FAM134A,BLCAP,HES2,SPR,FAM101B,SPSB1,PHF1,CALR,AKIRIN1,RPS6KA2,CA2,RALGPS2,CRY2,ERCC2,MAP3K3,TIMP2,COL6A2,CTNNAL1,MEST,TCN2,BSDC1,NFIX,NCOA3,RPL12,COQ10A,NR1D2,CANT1,PITPNA,ST3GAL1,USF2,JARID2,ABCG1 |
| 2.144e-02 | -3.84 | - | gene3d domains | 2.70.150.10 | 32 | 10 | 9988 | 1574 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP13A3,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 2.144e-02 | -3.84 | - | gene3d domains | 3.40.1110.10 | 32 | 10 | 9988 | 1574 |
ATP1A1,ATP9A,ATP8A1,ATP7B,ATP13A3,ATP8B1,ATP8B3,ATP10D,ATP2B1,ATP13A2 |
| 2.145e-02 | -3.84 | Gal_mutarotase_SF_dom | interpro domains | IPR011013 | 12 | 5 | 18293 | 2672 |
MAN2A2,MGAM,MAN2B2,GAA,GALM |
| 2.146e-02 | -3.84 | AP2TNSCPFCT | prints domains | PR01748 | 5 | 3 | 4759 | 661 |
TFAP2C,TFAP2A,TFAP2E |
| 2.146e-02 | -3.84 | PDGF_ERK_DN.V1_DN | MSigDB lists | PDGF_ERK_DN.V1_DN | 142 | 30 | 17758 | 2588 |
MAP3K3,LTBP1,TGIF1,BCL9,BCL7B,PHLPP1,CCNF,APC2,ARHGEF16,RHOB,DNAJB9,SAC3D1,BCL10,BTG1,LRRC6,PPP1R10,MGAT1,CNTRL,NFKBIA,FBXL14,CDKN1B,IRF2,FAM102A,ARF6,MAD2L1BP,SPRY2,MAFF,PPP6R1,DUSP1,CKS2 |
| 2.146e-02 | -3.84 | ORGAN_MORPHOGENESIS | MSigDB lists | ORGAN_MORPHOGENESIS | 142 | 30 | 17758 | 2588 |
GAA,SOD1,PAX6,CCM2,COL18A1,HTATIP2,AES,IL18,PLAC1,NOTCH2,RASA1,RHOB,PITX2,BTG1,DGCR2,ACVRL1,HTT,SCG2,TBX1,BAX,ERAP1,TLE1,EGFL7,PKD2,EPHB4,ETV7,SHROOM2,SPRY2,SYK,FGD1 |
| 2.146e-02 | -3.84 | TCATCTC,MIR-143 | MSigDB lists | TCATCTC,MIR-143 | 142 | 30 | 17758 | 2588 |
RMND5A,PHF20L1,LASP1,TAOK2,RBM24,GRHL2,RALBP1,TSC22D3,ITGA6,KLC2,RNF165,TRAPPC8,GALNT7,SEPT4,SIX4,MAP1B,GABARAPL1,GNS,ADD3,LMO4,AMMECR1,TUBGCP6,ITPR1,FAM117A,CTNND1,ERBB3,MAP3K7,AKIP1,MAPK7,EGLN1 |
| 2.154e-02 | -3.84 | phosphatidylinositol 3-kinase complex, class IA | cellular component | GO:0005943 | 2 | 2 | 17570 | 2579 |
PIK3R1,PIK3CA |
| 2.154e-02 | -3.84 | TRAF2-GSTP1 complex | cellular component | GO:0097057 | 2 | 2 | 17570 | 2579 |
GSTP1,TRAF2 |
| 2.154e-02 | -3.84 | nuclear aryl hydrocarbon receptor complex | cellular component | GO:0034753 | 2 | 2 | 17570 | 2579 |
AHRR,AHR |
| 2.154e-02 | -3.84 | multivesicular body, internal vesicle | cellular component | GO:0097487 | 2 | 2 | 17570 | 2579 |
CD63,EGFR |
| 2.154e-02 | -3.84 | MutSalpha complex | cellular component | GO:0032301 | 2 | 2 | 17570 | 2579 |
MSH6,MSH2 |
| 2.154e-02 | -3.84 | procollagen-proline 4-dioxygenase complex | cellular component | GO:0016222 | 2 | 2 | 17570 | 2579 |
P4HB,P4HA2 |
| 2.154e-02 | -3.84 | Scrib-APC-beta-catenin complex | cellular component | GO:0034750 | 2 | 2 | 17570 | 2579 |
SCRIB,CTNNB1 |
| 2.154e-02 | -3.84 | integrin alphav-beta8 complex | cellular component | GO:0034686 | 2 | 2 | 17570 | 2579 |
ITGAV,ITGB8 |
| 2.154e-02 | -3.84 | glutamate-cysteine ligase complex | cellular component | GO:0017109 | 2 | 2 | 17570 | 2579 |
GCLM,GCLC |
| 2.154e-02 | -3.84 | oncostatin-M receptor complex | cellular component | GO:0005900 | 2 | 2 | 17570 | 2579 |
OSMR,IL6ST |
| 2.155e-02 | -3.84 | HIF1A (hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)) | protein interactions | 3091 | 136 | 31 | 16036 | 2547 |
LAMP2,SMARCA2,FAF2,RUNX2,TCEB2,EPAS1,NR4A1,SAT1,TP53,FHL2,EAF2,F12,PKM,HDAC6,KDM3A,VCP,RB1,CTNNB1,BHLHE41,WWTR1,DCUN1D1,HDAC1,ARNT2,PLD1,CITED2,EGLN3,SAT2,ARNT,NCOA2,CAPN1,EGLN1 |
| 2.158e-02 | -3.84 | RNF mutants show enhanced WNT signaling and proliferation | REACTOME pathways | R-HSA-5340588 | 8 | 4 | 8202 | 1235 |
FZD5,WNT3A,FZD4,FZD6 |
| 2.158e-02 | -3.84 | Negative regulation of the PI3K/AKT network | REACTOME pathways | R-HSA-199418 | 8 | 4 | 8202 | 1235 |
PHLPP1,AKT1,PTEN,PHLPP2 |
| 2.158e-02 | -3.84 | Sema4D mediated inhibition of cell attachment and migration | REACTOME pathways | R-HSA-416550 | 8 | 4 | 8202 | 1235 |
RHOA,SEMA4D,RND1,ARHGAP35 |
| 2.161e-02 | -3.83 | Lactamase_B | pfam domains | PF00753 | 8 | 4 | 16629 | 2504 |
LACTB2,ETHE1,PNKD,HAGHL |
| 2.161e-02 | -3.83 | negative regulation of dephosphorylation | biological process | GO:0035305 | 79 | 19 | 16441 | 2455 |
CAMSAP3,SPRED1,FARP1,BAG4,LMTK3,PPP4R4,IQGAP1,PKMYT1,TIPRL,SH2D4A,SYTL2,SH3RF2,SWAP70,SEMA4D,PPP2R4,CRY2,DLG3,CHP1,ARFGEF3 |
| 2.163e-02 | -3.83 | LEE_DOUBLE_POLAR_THYMOCYTE | MSigDB lists | LEE_DOUBLE_POLAR_THYMOCYTE | 25 | 8 | 17758 | 2588 |
RMND5A,CD8A,MCTP1,C3orf52,BCL6,CPLX1,CYP2U1,LHFPL2 |
| 2.163e-02 | -3.83 | EXTRINSIC_TO_MEMBRANE | MSigDB lists | EXTRINSIC_TO_MEMBRANE | 25 | 8 | 17758 | 2588 |
GNAS,MUC16,PLAUR,ARRB1,EZR,SYTL4,APC2,SYTL2 |
| 2.163e-02 | -3.83 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP | 25 | 8 | 17758 | 2588 |
BTG1,ENPP1,PARP12,RBM47,GALNT12,RUNX3,TCN2,ZNF385B |
| 2.163e-02 | -3.83 | LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY | MSigDB lists | LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY | 25 | 8 | 17758 | 2588 |
THRB,NR3C1,THRA,NR4A3,RARG,AHR,NR2C1,NR3C2 |
| 2.163e-02 | -3.83 | BIOCARTA_MCALPAIN_PATHWAY | MSigDB lists | BIOCARTA_MCALPAIN_PATHWAY | 25 | 8 | 17758 | 2588 |
CAPN2,MYLK,EZR,PRKAR2B,CAPNS1,EGFR,CAPN1,PRKAR1A |
| 2.164e-02 | -3.83 | heart valve development | biological process | GO:0003170 | 29 | 9 | 16441 | 2455 |
BMP2,ACVR1,CYR61,SOX9,GATA3,TWIST1,NOTCH2,EFNA1,SHOX2 |
| 2.164e-02 | -3.83 | placenta blood vessel development | biological process | GO:0060674 | 29 | 9 | 16441 | 2455 |
HES1,HS6ST1,ITGB8,AKT1,CYR61,PKD2,FZD5,TMED2,SOCS3 |
| 2.164e-02 | -3.83 | positive regulation of calcium ion transmembrane transporter activity | biological process | GO:1901021 | 29 | 9 | 16441 | 2455 |
CALM2,STIM1,HTT,CALM1,PLCG2,CALM3,PKD2,ATP1B1,HSPA2 |
| 2.164e-02 | -3.83 | positive regulation of cartilage development | biological process | GO:0061036 | 29 | 9 | 16441 | 2455 |
BMP2,RUNX2,CYR61,ACVRL1,SOX9,FGF18,BMP1,LOXL2,POR |
| 2.164e-02 | -3.83 | positive regulation of calcium ion transmembrane transport | biological process | GO:1904427 | 29 | 9 | 16441 | 2455 |
CALM2,STIM1,HTT,CALM1,PLCG2,CALM3,PKD2,ATP1B1,HSPA2 |
| 2.167e-02 | -3.83 | VEGF signaling pathway | KEGG pathways | ko04370 | 61 | 16 | 6908 | 1076 |
PLA2G4A,AKT1,MAPKAPK3,PIK3R1,CASP9,MAPKAPK2,PLCG1,RAC2,PTGS2,PLCG2,PIK3CA,MAPK13,MAPK11,PIK3CD,HSPB1,MAPK12 |
| 2.167e-02 | -3.83 | VEGF signaling pathway | KEGG pathways | hsa04370 | 61 | 16 | 6908 | 1076 |
PLA2G4A,AKT1,MAPKAPK3,PIK3R1,CASP9,MAPKAPK2,PLCG1,RAC2,PTGS2,PLCG2,PIK3CA,MAPK13,MAPK11,PIK3CD,HSPB1,MAPK12 |
| 2.168e-02 | -3.83 | MAP1LC3A (microtubule-associated protein 1 light chain 3 alpha) | protein interactions | 84557 | 110 | 26 | 16036 | 2547 |
PINK1,LGALS3,TNIP1,EPAS1,TUBB4B,TBC1D1,BNIP3L,TP53INP2,MAP1LC3B,PGAP1,EGFR,VCP,MAP1B,OPTN,GABARAPL1,TBC1D17,PRKAG2,HTT,RRBP1,PRKCI,CBX5,HSPA2,DVL2,FAM134C,TUBA4A,TBC1D10B |
| 2.169e-02 | -3.83 | response to hydrogen peroxide | biological process | GO:0042542 | 95 | 22 | 16441 | 2455 |
PPIF,SIRT1,KLF2,CASP3,SOD1,PRKAA1,HDAC6,ETS1,SDC1,RHOB,PDCD10,STK26,PRDX3,AREG,CST3,NR4A3,AKR1B1,OSER1,MAPK7,MAP3K5,CYP1B1,DUSP1 |
| 2.169e-02 | -3.83 | alpha-amino acid catabolic process | biological process | GO:1901606 | 95 | 22 | 16441 | 2455 |
PRODH,SHMT1,ALDH6A1,GCAT,AASS,CRYM,HAL,ASL,MCCC1,CCBL2,OAT,AMDHD1,DDAH1,ABHD12,ALDH7A1,GOT1,AHCY,HMGCL,ACAD8,GAD1,MCCC2,FAH |
| 2.169e-02 | -3.83 | cellular response to reactive oxygen species | biological process | GO:0034614 | 95 | 22 | 16441 | 2455 |
PPIF,SIRT1,KLF2,SOD1,NQO1,TRAF2,PRKAA1,SOD2,HDAC6,FOS,ETS1,RHOB,PDCD10,PRDX3,CST3,DNM2,AKR1B1,OSER1,PKD2,MAPK7,MAP3K5,CYP1B1 |
| 2.174e-02 | -3.83 | Melanoma | KEGG pathways | hsa05218 | 71 | 18 | 6908 | 1076 |
PDGFC,AKT1,PIK3R1,TP53,PDGFB,FGF19,EGFR,CCND1,PDGFA,RB1,CDH1,IGF1R,PTEN,FGF18,MITF,E2F1,PIK3CA,PIK3CD |
| 2.174e-02 | -3.83 | Melanoma | KEGG pathways | ko05218 | 71 | 18 | 6908 | 1076 |
PDGFC,AKT1,PIK3R1,TP53,PDGFB,FGF19,EGFR,CCND1,PDGFA,RB1,CDH1,IGF1R,PTEN,FGF18,MITF,E2F1,PIK3CA,PIK3CD |
| 2.177e-02 | -3.83 | Long-term potentiation | KEGG pathways | ko04720 | 66 | 17 | 6908 | 1076 |
RPS6KA1,CALM1,GRIN1,CALM3,ITPR2,ITPR3,PRKACA,GRM5,CALM2,RPS6KA2,ITPR1,PPP1CB,GRIN2D,PPP1CA,PLCB2,CAMK2G,RPS6KA3 |
| 2.177e-02 | -3.83 | Long-term potentiation | KEGG pathways | hsa04720 | 66 | 17 | 6908 | 1076 |
RPS6KA1,CALM1,GRIN1,CALM3,ITPR2,ITPR3,PRKACA,GRM5,CALM2,RPS6KA2,ITPR1,PPP1CB,GRIN2D,PPP1CA,PLCB2,CAMK2G,RPS6KA3 |
| 2.186e-02 | -3.82 | regulation of protein import into nucleus | biological process | GO:0042306 | 167 | 35 | 16441 | 2455 |
DDX58,TXN,NFKBIE,THRA,RAB23,PSMD10,TGFBR1,IL18,APC2,IL18R1,NOV,CDH1,DACT1,BMP7,CABP1,SMO,DAB2IP,MDFIC,WNT3A,MAPK7,MDFI,CHP1,SIRT1,RHOA,PIK3R1,LITAF,PRKCQ,FZD7,EGFR,PTGS2,NFKBIA,WWTR1,PKD2,PKIA,TMEM173 |
| 2.186e-02 | -3.82 | MODULE_17 | MSigDB lists | MODULE_17 | 356 | 66 | 17758 | 2588 |
S100A11,PTTG1,IL27RA,KIF2C,BCL2L1,CCNB1,ECI1,CHPF,IER3,APOBEC3B,ZYX,WEE1,PCNA,CCNA2,KIF14,DDHD2,PSMC2,DNM2,GOT1,RNASEH2A,CKS2,PLK1,ACBD3,CDC20,AURKB,PKMYT1,MCFD2,GTF2A2,ITPR3,CDK1,PRIM1,MDK,IARS2,PPP2R5D,INPPL1,BLVRB,GDF15,TRIB2,DHRS3,HOXB2,CKAP5,TFAP4,TOP2A,RAC2,PDCD10,CDK16,CTSC,GATA2,NECAB3,MSH2,SRP54,AHCY,PIM1,TMX1,PIGC,GFPT1,HMMR,HES1,ZWINT,PYGL,EMP3,RNPEP,PSMA4,NMI,CCNB2,ACOT7 |
| 2.187e-02 | -3.82 | perinuclear endoplasmic reticulum | cellular component | GO:0097038 | 12 | 5 | 17570 | 2579 |
CAPN2,OSBPL7,OSBPL3,DBI,PIK3R1 |
| 2.189e-02 | -3.82 | V$PAX4_04 | MSigDB lists | V$PAX4_04 | 206 | 41 | 17758 | 2588 |
CCNI,HOXB7,CHCHD7,VANGL1,RHBDL3,MORF4L2,SIX4,WWP2,FOXP2,ITGA3,IGF1R,PPP1R10,ANKS1B,RGS3,CALD1,LMO4,BCL6,FAM63A,KLF9,MYT1,ZNF462,ASXL1,DUSP4,ELK1,ITPR3,NFIB,EBF2,NFIX,CNOT2,PITX2,MPRIP,HOXA9,RAP2C,MYLK,E2F1,MAP3K11,C1orf43,RTN3,LRRC57,KLF7,JARID2 |
| 2.189e-02 | -3.82 | V$HNF3B_01 | MSigDB lists | V$HNF3B_01 | 206 | 41 | 17758 | 2588 |
RUNX2,FRMD4A,CPEB4,CHCHD7,CYP2J2,FLOT1,IER3,TFAP4,FOXP2,KCTD15,ARTN,PPP1R10,CYR61,SLC16A6,CALD1,LMO4,FUT8,SLC44A1,MITF,KLF3,BUB1,CITED2,CLIP2,SULF2,DUSP1,CYP26B1,SSH3,HN1L,CTNNAL1,RGAG1,RAB3IP,NFIB,NFIX,KLF12,COL13A1,PELI2,NKD1,PPP1CB,CDAN1,RARG,TOB1 |
| 2.190e-02 | -3.82 | PLK4 (polo-like kinase 4) | protein interactions | 10733 | 15 | 6 | 16036 | 2547 |
TAX1BP3,TGFBR1,TEC,FAM46C,FBXW5,PLK4 |
| 2.190e-02 | -3.82 | GRM1 (glutamate receptor, metabotropic 1) | protein interactions | 2911 | 15 | 6 | 16036 | 2547 |
TRPC1,ADORA1,ADRBK1,HTT,ITPR1,OPTN |
| 2.190e-02 | -3.82 | ADK (adenosine kinase) | protein interactions | 132 | 15 | 6 | 16036 | 2547 |
DAZAP1,SOD1,NQO1,PCBP1,FICD,CAPG |
| 2.190e-02 | -3.82 | TRIM13 (tripartite motif containing 13) | protein interactions | 10206 | 15 | 6 | 16036 | 2547 |
GMCL1,DDOST,AKT1,CALM1,VCP,UBE2D2 |
| 2.190e-02 | -3.82 | MYL9 (myosin light chain 9) | protein interactions | 10398 | 15 | 6 | 16036 | 2547 |
TP73,MYH14,HSPB1,MYL12A,TP53,PIP4K2C |
| 2.190e-02 | -3.82 | SFTPC (surfactant protein C) | protein interactions | 6440 | 15 | 6 | 16036 | 2547 |
DNAJC10,WWP1,SEC61G,VCP,DNAJB9,WWP2 |
| 2.190e-02 | -3.82 | WNK4 (WNK lysine deficient protein kinase 4) | protein interactions | 65266 | 15 | 6 | 16036 | 2547 |
KLHL2,SGK1,CLDN4,STK39,AKT1,BCL6 |
| 2.190e-02 | -3.82 | CNTNAP3 (contactin associated protein-like 3) | protein interactions | 79937 | 15 | 6 | 16036 | 2547 |
NRG1,NAAA,ERLEC1,APBA1,ANTXR1,HLA-E |
| 2.190e-02 | -3.82 | TRPC6 (transient receptor potential cation channel, subfamily C, member 6) | protein interactions | 7225 | 15 | 6 | 16036 | 2547 |
MX1,TRPC1,FYN,ITPR3,TRPC3,ITPR1 |
| 2.190e-02 | -3.82 | AKAP5 (A kinase (PRKA) anchor protein 5) | protein interactions | 9495 | 15 | 6 | 16036 | 2547 |
PRKAR2B,PRKACA,IQGAP1,CALM1,RET,DLG1 |
| 2.190e-02 | -3.82 | SLC25A24 (solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24) | protein interactions | 29957 | 15 | 6 | 16036 | 2547 |
CD55,FAF2,FBXO6,SLC25A4,SLC25A5,FLOT1 |
| 2.190e-02 | -3.82 | SELPLG (selectin P ligand) | protein interactions | 6404 | 15 | 6 | 16036 | 2547 |
SELL,TNIP1,SYK,BACE1,PIK3R1,TPST1 |
| 2.190e-02 | -3.82 | Tubg1 (tubulin, gamma 1) | protein interactions | 103733 | 15 | 6 | 16036 | 2547 |
TUBG1,MZT2A,MZT1,PRICKLE3,LGALS3BP,TUBGCP6 |
| 2.190e-02 | -3.82 | ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A) | protein interactions | 23294 | 15 | 6 | 16036 | 2547 |
ERBB2,TRIM47,PACSIN2,DNPEP,EGFR,DEF6 |
| 2.190e-02 | -3.82 | STT3A (STT3A, subunit of the oligosaccharyltransferase complex (catalytic)) | protein interactions | 3703 | 15 | 6 | 16036 | 2547 |
UNC93B1,FBXO6,HJURP,ITM2C,EGFR,TMEM173 |
| 2.191e-02 | -3.82 | Small_GTPase_Rho | interpro domains | IPR003578 | 25 | 8 | 18293 | 2672 |
RAC2,RHOA,RND3,RAP2C,RHOBTB2,RHOB,RHEB,RND1 |
| 2.191e-02 | -3.82 | PLCB3 (phospholipase C, beta 3 (phosphatidylinositol-specific)) | protein interactions | 5331 | 19 | 7 | 16036 | 2547 |
SNTA1,CALM3,RGS12,TRPC3,SLC9A3R2,CAMK2G,PRKG1 |
| 2.191e-02 | -3.82 | PITPNA (phosphatidylinositol transfer protein, alpha) | protein interactions | 5306 | 19 | 7 | 16036 | 2547 |
PLCG1,GOT1,MLKL,MORF4L2,HSPB1,EGFR,NEO1 |
| 2.191e-02 | -3.82 | VRK2 (vaccinia related kinase 2) | protein interactions | 7444 | 19 | 7 | 16036 | 2547 |
FAF2,MAP3K7,ILK,MAPK8IP1,LMNA,SPINT2,TP53 |
| 2.191e-02 | -3.82 | SHANK2 (SH3 and multiple ankyrin repeat domains 2) | protein interactions | 22941 | 19 | 7 | 16036 | 2547 |
DLGAP1,CTTN,ARHGEF7,ADGRB2,SHARPIN,MYO5A,DNM2 |
| 2.191e-02 | -3.82 | BNIP3 (BCL2/adenovirus E1B 19kDa interacting protein 3) | protein interactions | 664 | 19 | 7 | 16036 | 2547 |
HDAC1,BCL2L1,MAP1LC3B,TMEM30A,KTN1,RHEB,BNIP3L |
| 2.191e-02 | -3.82 | RTN3 (reticulon 3) | protein interactions | 10313 | 19 | 7 | 16036 | 2547 |
PPP2R3C,FXR2,ATP1B3,CDIPT,FAM160A2,RTN3,PTPN9 |
| 2.197e-02 | -3.82 | secretion | biological process | GO:0046903 | 602 | 108 | 16441 | 2455 |
PLA2G4A,DOC2A,ARFGEF1,P2RX7,GATA3,UBE2Q1,LGI3,BAIAP3,SYTL4,CACNB4,PDGFB,DDR1,ERP29,SDF4,SYTL2,TP73,CALM2,CCND1,PDGFA,SVBP,RAB15,CTGF,STEAP2,TRPC1,STEAP3,PIK3CD,ARL4D,RAB27B,S100A13,RASGRP1,TUBA4A,CHP1,LAMP2,SOD1,CELSR2,FZD4,DMTN,RNF19B,OPTN,TRIM9,ALDH5A1,AXL,ATP7B,GNPTAB,RAB11FIP1,NOD2,MAOA,SYT13,F2RL1,TC2N,ABCA1,PCSK5,ANXA3,CD63,HABP4,CALM3,BTN3A1,PLD2,SLC1A3,APBA1,MERTK,ITGA2B,PDIA4,ANK1,TIMP1,CA2,LLGL2,GATA2,CDK16,RIMS3,NECAB3,KCNN4,EXOC8,CD9,PRKCI,CADPS2,CPLX1,GAD1,SYK,SYTL3,CAMK2G,RIMS2,MYO5A,RAB3B,CASK,FBLN5,CALM1,FURIN,VAMP3,BTN3A2,SCRIB,AKAP3,STX3,SCRN2,GNAS,SERPINA1,RAB11FIP2,SYT7,SCG2,HTT,RAB31,NR4A3,ARFGAP3,LTBP2,PLD1,USF2,XDH,SNPH |
| 2.200e-02 | -3.82 | intracellular non-membrane-bounded organelle | cellular component | GO:0043232 | 3658 | 576 | 17570 | 2579 |
TRIM24,ADD1,MRPS15,TRIM5,PNPLA2,XIAP,SMARCAL1,CNTROB,MORF4L2,SYTL4,KIF26A,PHF1,TP73,NPM2,CALM2,WEE1,ZYX,RGS12,DNAH6,CABP1,DNM2,TUBG1,PPP1CA,ODF2L,APOBEC3G,TUBA4A,SPEF2,SMARCA2,DSTN,UXT,SPRTN,PRKAR2B,LOXL2,MYOM1,GINS4,LCP1,CARHSP1,MPRIP,MID1IP1,CAMK2N2,WDR11,DNM1L,TRAF3IP1,MYLK,NOD2,MAP3K11,HDAC1,MRPS28,TMOD2,RELL1,HSPB1,STARD13,ANXA11,SCN5A,NUAK1,FAM21C,LMNA,FLII,RAC2,ZCCHC17,FRY,NEK2,SLAIN2,MYLIP,NUP85,C9orf72,TTLL1,REC8,KIF20A,SALL4,PYM1,FHL2,MYBL2,PLS1,KIF20B,SRSF5,ILK,PSMA4,DCP2,PLIN5,NCOA3,FNTA,HTT,SETD3,ITPR1,DGAT2,AURKA,MDH1,STK39,DRP2,NDE1,ARPC2,CFAP20,CBX5,RUSC1,MTM1,TMSB15A,TUBB4B,ACTR8,PKP2,NUF2,PRKACA,APC2,APPBP2,SCNN1A,CDH1,SP100,ACSL4,ARL4D,ZNF365,ETV4,SNX10,RNF169,CAMSAP3,SSH3,PSRC1,RIPK2,APOBEC3D,AGPS,SEPT6,SYNE2,CYS1,VPS4B,CDCA2,NUSAP1,GABARAPL1,PDLIM3,SHROOM3,CORO1C,SIPA1L1,RGS14,GEN1,TTC8,FARP1,MZT1,TAOK2,CKAP2,SDC4,HABP4,RASSF7,FLOT1,TMA16,IFT27,CAPN2,ANK1,ADD3,IRAK1,CALD1,CST3,TUBGCP6,KLC3,SGCB,TMX1,POU6F1,LCA5,PLSCR1,CTNNAL1,TACC1,FMN1,UBE2A,PLEKHA7,RAB3IP,SNTB1,SKA1,ABLIM2,LDLRAP1,RPL12,CCDC6,SSNA1,HMGA1,CENPE,NUP37,SRSF9,FOXA1,PHC1,MYL9,SUDS3,ARFGEF1,NDC80,NDRG2,F11R,HDAC6,SPTB,INPP5E,PCNA,RPS6KA2,CTNNB1,NPNT,CNTRL,PSMC2,DDHD2,ABCA2,TLN2,NEB,CCDC38,PLK1,KRT80,THRB,PCGF5,MARK1,STAU2,CBX6,C12orf65,CKAP2L,EZR,KLK6,ANLN,CDK1,VCP,DPYSL3,KDM4D,DZIP1L,TNS4,TRIM9,PLEKHG6,MAP2,WIPI1,EPB41L4A,MYL12B,RUNX2,USH1C,BMF,HJURP,SORBS3,RACGAP1,SSX2IP,CORO1B,MYO5C,RB1,VASP,RINL,KIF13B,TBCD,MDFIC,MPHOSPH9,CKAP4,C9orf9,MRPS33,CORO2A,KBTBD8,G2E3,SMN1,CDK5R1,MAPKAPK2,H1F0,ZDHHC7,CCNB2,RAD21,NF2,UPF3B,TP53,BAHD1,STIL,BCAP31,TMSB15B,PER2,TTC21B,KMT5C,TACC2,BCL6,PLK4,ESPN,NOTCH3,LMAN1,SIRT1,AKT1,FIGNL1,CCSAP,CDC20,SERTAD3,MYL12A,DAG1,XRCC3,RPL22,BTBD6,BIN1,PINK1,PACSIN2,CTSB,SWI5,CDCA8,ERI2,ERCC6L,PSMD10,NKRF,HMGN3,DNAJB9,H1FX,CCDC92,CEP97,TBC1D31,CDK16,GTF2F2,TFAP2A,TRIM21,BUB1,RHOA,HMGN5,FXR2,BCAR1,BBS2,BCL10,DDX23,CNOT2,CDCA7L,FGF18,E2F1,PGRMC1,PPP2R3C,PKD2,ZBTB33,DIS3L,CFAP74,SSH1,FAM129B,KLC2,GATA3,PJA2,SEPT4,CCNB1,FAM101B,CENPN,PICK1,STIM1,ZFP36,HYLS1,ZBTB18,LOC81691,SGCE,KIFC2,SNTB2,KIF13A,TNS1,AGO4,AURKB,PIF1,CCNF,SLC25A5,PRIM1,PLK2,FAM110C,TRAF5,FGD1,DDX58,MRPL44,INPPL1,FRMD4A,DGKQ,KIF23,TXNDC9,PSIP1,RPL39,DAPK1,MSH2,CACNA1D,EEF1D,DNAI1,EPB41L5,B9D2,CEP89,CALM1,WHSC1,NFIB,FRMD4B,PLEKHH2,FAM64A,FAAH,WDR19,FAM83D,AGBL5,FGD6,PLIN3,HOOK1,IRF1,EHD1,FRMPD3,KIF3C,TCTN2,DLGAP5,CEP70,TRIP10,NDRG1,CCDC110,IQGAP1,SUZ12,RPS6KA1,BCL2L1,AIFM2,MNS1,PDE4D,FLOT2,MYO5B,CDKN2AIP,CAPN6,FOXJ2,DMTN,UTRN,TEP1,KIF1C,RAD17,ITPR3,H2AFV,SP4,CEP162,NIN,FYN,PPP2R5A,JAK1,STK26,STAT1,TRIOBP,PPP1CB,RAB29,COBL,CBX7,MRPS9,WASF3,CENPI,NES,APOBEC3H,SPDL1,DNAH3,CKAP5,RND1,SNTA1,FAM111A,RNF128,PHF7,PPP1R10,CENPJ,PRC1,ERCC2,CITED2,SPRY2,MSH6,SMC4,FARP2,CASK,ZWINT,MPP1,PARP4,DIAPH2,YES1,AIF1L,KIF11,CPTP,DCTN6,NUCB1,CTNS,GPER1,WDR62,ESPL1,FAF2,CPT2,KIF2C,MAP1LC3B,TRIM68,SH3KBP1,TSEN34,METTL7A,DPYSL2,CEP78,PHTF1,DLG1,CAPG,TRPC1,ASH2L,KIF22,RP2,CTTN,MYH14,MYRIP,STK35,CENPA,ASXL1,FOPNL,ARHGDIB,MRPS18A,MRPS36,STK17B,NEIL1,GPRC5B,TDRD7,PIFO,LASP1,ARAP3,PPP1R12A,CALM3,TEC,PRKCI,SRP54,KNTC1,LRIF1,HP1BP3,TPGS2,OXR1,HMG20B,NUBP1,RANBP9,TSC1,NUDT16,UTP14C,CDCA5,PAPD5,KIF12,SHROOM2,JAK3,AFAP1,RARG,GAS2L1,DYNLRB1,PAX6,SORBS1,SPC25,TDRKH,ZMYND10,PATL2,MICALL2,PHLDA1,LRRC45,SS18,SETDB2,KIF14,EPB41L4B,HSPA2,CHP1,TAF5,MRPS35,ARHGAP35,BFSP1,STAT6,TLE1,SPTBN5,SGOL1,REEP4,MAD2L1BP,FBLIM1,FRMD6,POC1B,CIT,SHPRH,TRIB2,SAC3D1,TOP2A,KIF5B,MZT2A,TAF1B,LLGL2,RRBP1,ACTA2,H2AFY,CLIP2,RPGR,MYO5A,PGM1,SUN2,ADAM17,CENPC,CFAP46,ASPM,SYBU,RC3H2,RGCC,RUNX3,POLD3,MPV17L2,SPAG1,MAP1B,ARHGAP24,KLHL2,CTSV,UACA,ARRB1,GEM,CEP41,SNPH |
| 2.200e-02 | -3.82 | non-membrane-bounded organelle | cellular component | GO:0043228 | 3658 | 576 | 17570 | 2579 |
TRIM24,ADD1,MRPS15,TRIM5,PNPLA2,XIAP,SMARCAL1,CNTROB,MORF4L2,SYTL4,KIF26A,PHF1,TP73,NPM2,CALM2,WEE1,ZYX,RGS12,DNAH6,CABP1,DNM2,TUBG1,PPP1CA,ODF2L,APOBEC3G,TUBA4A,SPEF2,SMARCA2,DSTN,UXT,SPRTN,PRKAR2B,LOXL2,MYOM1,GINS4,LCP1,CARHSP1,MPRIP,MID1IP1,CAMK2N2,WDR11,DNM1L,TRAF3IP1,MYLK,NOD2,MAP3K11,HDAC1,MRPS28,TMOD2,RELL1,HSPB1,STARD13,ANXA11,SCN5A,NUAK1,FAM21C,LMNA,FLII,RAC2,ZCCHC17,FRY,NEK2,SLAIN2,MYLIP,NUP85,C9orf72,TTLL1,REC8,KIF20A,SALL4,PYM1,FHL2,MYBL2,PLS1,KIF20B,SRSF5,ILK,PSMA4,DCP2,PLIN5,NCOA3,FNTA,HTT,SETD3,ITPR1,DGAT2,AURKA,MDH1,STK39,NDE1,DRP2,ARPC2,CFAP20,CBX5,RUSC1,MTM1,TMSB15A,TUBB4B,ACTR8,PKP2,NUF2,PRKACA,APC2,APPBP2,SCNN1A,CDH1,SP100,ACSL4,ARL4D,ZNF365,ETV4,SNX10,RNF169,CAMSAP3,SSH3,PSRC1,RIPK2,APOBEC3D,AGPS,SEPT6,SYNE2,CYS1,VPS4B,CDCA2,NUSAP1,GABARAPL1,PDLIM3,SHROOM3,CORO1C,SIPA1L1,RGS14,GEN1,TTC8,FARP1,MZT1,TAOK2,CKAP2,SDC4,HABP4,RASSF7,FLOT1,TMA16,IFT27,CAPN2,ANK1,ADD3,IRAK1,CALD1,CST3,TUBGCP6,KLC3,SGCB,TMX1,POU6F1,LCA5,PLSCR1,CTNNAL1,TACC1,FMN1,UBE2A,PLEKHA7,RAB3IP,SNTB1,SKA1,ABLIM2,LDLRAP1,RPL12,CCDC6,SSNA1,HMGA1,CENPE,NUP37,SRSF9,FOXA1,PHC1,MYL9,SUDS3,ARFGEF1,NDC80,NDRG2,F11R,HDAC6,SPTB,INPP5E,PCNA,RPS6KA2,CTNNB1,NPNT,CNTRL,PSMC2,DDHD2,ABCA2,TLN2,NEB,CCDC38,PLK1,KRT80,THRB,PCGF5,MARK1,STAU2,CBX6,C12orf65,CKAP2L,EZR,KLK6,ANLN,CDK1,VCP,DPYSL3,KDM4D,DZIP1L,TNS4,TRIM9,PLEKHG6,MAP2,WIPI1,EPB41L4A,MYL12B,RUNX2,USH1C,BMF,HJURP,SORBS3,RACGAP1,SSX2IP,CORO1B,MYO5C,RB1,VASP,RINL,KIF13B,TBCD,MDFIC,MPHOSPH9,CKAP4,C9orf9,MRPS33,CORO2A,KBTBD8,G2E3,SMN1,CDK5R1,MAPKAPK2,H1F0,ZDHHC7,CCNB2,RAD21,NF2,UPF3B,TP53,BAHD1,STIL,BCAP31,TMSB15B,PER2,TTC21B,KMT5C,TACC2,BCL6,PLK4,ESPN,NOTCH3,LMAN1,SIRT1,AKT1,FIGNL1,CCSAP,CDC20,SERTAD3,MYL12A,DAG1,XRCC3,RPL22,BTBD6,BIN1,PINK1,PACSIN2,CTSB,SWI5,CDCA8,ERI2,ERCC6L,PSMD10,NKRF,HMGN3,DNAJB9,H1FX,CCDC92,CEP97,TBC1D31,CDK16,GTF2F2,TFAP2A,TRIM21,BUB1,RHOA,HMGN5,FXR2,BCAR1,BBS2,BCL10,DDX23,CNOT2,CDCA7L,FGF18,E2F1,PGRMC1,PPP2R3C,PKD2,ZBTB33,DIS3L,CFAP74,SSH1,FAM129B,KLC2,GATA3,PJA2,SEPT4,CCNB1,FAM101B,CENPN,PICK1,STIM1,ZFP36,HYLS1,ZBTB18,LOC81691,SGCE,KIFC2,SNTB2,KIF13A,TNS1,AGO4,AURKB,PIF1,CCNF,SLC25A5,PRIM1,PLK2,FAM110C,TRAF5,FGD1,DDX58,MRPL44,INPPL1,FRMD4A,DGKQ,KIF23,TXNDC9,PSIP1,RPL39,DAPK1,MSH2,CACNA1D,EEF1D,DNAI1,EPB41L5,B9D2,CEP89,CALM1,WHSC1,NFIB,FRMD4B,PLEKHH2,FAM64A,FAAH,WDR19,FAM83D,AGBL5,FGD6,PLIN3,HOOK1,IRF1,EHD1,FRMPD3,KIF3C,TCTN2,DLGAP5,CEP70,TRIP10,NDRG1,CCDC110,IQGAP1,SUZ12,RPS6KA1,BCL2L1,AIFM2,MNS1,PDE4D,FLOT2,MYO5B,CDKN2AIP,CAPN6,FOXJ2,DMTN,UTRN,TEP1,KIF1C,RAD17,ITPR3,H2AFV,SP4,CEP162,NIN,FYN,PPP2R5A,JAK1,STK26,STAT1,TRIOBP,PPP1CB,RAB29,COBL,CBX7,MRPS9,WASF3,CENPI,NES,APOBEC3H,SPDL1,DNAH3,CKAP5,RND1,SNTA1,FAM111A,RNF128,PHF7,PPP1R10,CENPJ,PRC1,ERCC2,CITED2,SPRY2,MSH6,SMC4,FARP2,CASK,ZWINT,MPP1,PARP4,DIAPH2,YES1,AIF1L,KIF11,CPTP,DCTN6,NUCB1,CTNS,GPER1,WDR62,ESPL1,FAF2,CPT2,KIF2C,MAP1LC3B,TRIM68,SH3KBP1,TSEN34,METTL7A,DPYSL2,CEP78,PHTF1,DLG1,CAPG,TRPC1,ASH2L,KIF22,RP2,CTTN,MYH14,MYRIP,STK35,CENPA,ASXL1,FOPNL,ARHGDIB,MRPS18A,MRPS36,STK17B,NEIL1,GPRC5B,TDRD7,PIFO,LASP1,ARAP3,PPP1R12A,CALM3,TEC,PRKCI,SRP54,KNTC1,LRIF1,HP1BP3,TPGS2,OXR1,HMG20B,NUBP1,RANBP9,TSC1,NUDT16,UTP14C,CDCA5,PAPD5,KIF12,SHROOM2,JAK3,AFAP1,RARG,GAS2L1,DYNLRB1,PAX6,SORBS1,SPC25,TDRKH,ZMYND10,PATL2,MICALL2,PHLDA1,LRRC45,SS18,SETDB2,KIF14,EPB41L4B,HSPA2,CHP1,TAF5,MRPS35,ARHGAP35,BFSP1,STAT6,TLE1,SPTBN5,SGOL1,REEP4,MAD2L1BP,FBLIM1,FRMD6,POC1B,CIT,SHPRH,TRIB2,SAC3D1,TOP2A,KIF5B,MZT2A,TAF1B,LLGL2,RRBP1,ACTA2,H2AFY,CLIP2,RPGR,MYO5A,PGM1,SUN2,ADAM17,CENPC,CFAP46,ASPM,SYBU,RC3H2,RGCC,RUNX3,POLD3,MPV17L2,SPAG1,MAP1B,ARHGAP24,KLHL2,CTSV,UACA,ARRB1,GEM,CEP41,SNPH |
| 2.202e-02 | -3.82 | GSE6269_FLU_VS_E_COLI_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_E_COLI_INF_PBMC_UP | 148 | 31 | 17758 | 2588 |
MX1,MLEC,PARP12,AGRN,IFITM3,USP18,STRN4,EMP3,HERC6,PDHX,LGALS3BP,HLA-A,CALR,HLA-B,NUCB1,ZYX,C19orf66,METTL7A,DNM2,ANKRD12,TMBIM6,TRIM21,RPN2,IRF7,USP1,OAS3,PDIA6,NRBP1,IFI6,KDELR1,EBAG9 |
| 2.203e-02 | -3.82 | negative regulation of sequence-specific DNA binding transcription factor activity | biological process | GO:0043433 | 139 | 30 | 16441 | 2455 |
SIRT1,SIGIRR,THRA,DAP,ITCH,PSMD10,ERBB2IP,FZD6,WWP2,CTNNBIP1,RB1,SP100,IRAK1,IGF1R,BMP7,SIVA1,WFS1,NFKBIA,PIAS2,NOD2,NLRC5,TRIM21,ARRB1,DAB2IP,TWIST1,PIM1,GFI1,EGLN1,CHP1,CYP1B1 |
| 2.207e-02 | -3.81 | Phospholipase C-mediated cascade; FGFR4 | REACTOME pathways | R-HSA-5654228 | 48 | 13 | 8202 | 1235 |
CALM2,PLCG1,ADRBK1,CALM1,FGF18,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,FGF19,PRKAR1A |
| 2.207e-02 | -3.81 | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | MSigDB lists | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | 65 | 16 | 17758 | 2588 |
PSMB4,PSME2,CDC20,PTTG1,PSMD7,PSMD10,PSME1,CCNB1,PSMA4,CDK1,PSMD1,PSMD3,PSMC2,UBE2C,PSMC1,PSMA5 |
| 2.207e-02 | -3.81 | RIGGINS_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_UP | 65 | 16 | 17758 | 2588 |
PRODH,ARMCX3,CELSR2,LRP4,RET,ASB13,ALDH3B1,TGFBR3,SRPX,SERPINA1,RGS3,CTSA,SPRY4,CTSD,ARMCX6,PTGES |
| 2.207e-02 | -3.81 | AMUNDSON_RESPONSE_TO_ARSENITE | MSigDB lists | AMUNDSON_RESPONSE_TO_ARSENITE | 212 | 42 | 17758 | 2588 |
GRN,ST13,IGFBP6,CPEB4,MAN1A2,CIT,TSC22D3,TAP1,ISYNA1,PLA2G16,BMP2K,ZFX,ACAP2,IL6ST,FJX1,HSPA13,MAPK7,CTH,ADAM17,SOD1,MMD,FHL2,NFE2L1,RUNX3,ANLN,ZFAND5,DAG1,ATP10D,LEPR,STK17A,TSC1,KLF12,ETS2,SH2D3C,STAT6,CTSA,GLA,ATP6V1C1,APBA2,MAFF,GOLGB1,CTDSP1 |
| 2.210e-02 | -3.81 | single thymine insertion binding | molecular function | GO:0032143 | 2 | 2 | 16491 | 2452 |
MSH6,MSH2 |
| 2.210e-02 | -3.81 | [acetyl-CoA carboxylase] kinase activity | molecular function | GO:0050405 | 2 | 2 | 16491 | 2452 |
PRKAA2,PRKAA1 |
| 2.210e-02 | -3.81 | myosin tail binding | molecular function | GO:0032029 | 2 | 2 | 16491 | 2452 |
SPTBN5,USH1C |
| 2.210e-02 | -3.81 | diamine N-acetyltransferase activity | molecular function | GO:0004145 | 2 | 2 | 16491 | 2452 |
SAT2,SAT1 |
| 2.210e-02 | -3.81 | xanthine dehydrogenase activity | molecular function | GO:0004854 | 2 | 2 | 16491 | 2452 |
XDH,AOX1 |
| 2.210e-02 | -3.81 | alpha-galactosidase activity | molecular function | GO:0004557 | 2 | 2 | 16491 | 2452 |
GLA,NAGA |
| 2.210e-02 | -3.81 | leukemia inhibitory factor receptor activity | molecular function | GO:0004923 | 2 | 2 | 16491 | 2452 |
LIFR,IL6ST |
| 2.210e-02 | -3.81 | galactoside 2-alpha-L-fucosyltransferase activity | molecular function | GO:0008107 | 2 | 2 | 16491 | 2452 |
FUT2,FUT1 |
| 2.210e-02 | -3.81 | flavin-linked sulfhydryl oxidase activity | molecular function | GO:0016971 | 2 | 2 | 16491 | 2452 |
QSOX1,QSOX2 |
| 2.210e-02 | -3.81 | long-chain-fatty-acyl-CoA reductase activity | molecular function | GO:0050062 | 2 | 2 | 16491 | 2452 |
FAR2,FAR1 |
| 2.210e-02 | -3.81 | glutamate-cysteine ligase activity | molecular function | GO:0004357 | 2 | 2 | 16491 | 2452 |
GCLM,GCLC |
| 2.210e-02 | -3.81 | interleukin-27 receptor activity | molecular function | GO:0045509 | 2 | 2 | 16491 | 2452 |
IL27RA,IL6ST |
| 2.210e-02 | -3.81 | sulfate adenylyltransferase activity | molecular function | GO:0004779 | 2 | 2 | 16491 | 2452 |
PAPSS2,PAPSS1 |
| 2.210e-02 | -3.81 | oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor | molecular function | GO:0016726 | 2 | 2 | 16491 | 2452 |
XDH,AOX1 |
| 2.210e-02 | -3.81 | nucleoside triphosphate adenylate kinase activity | molecular function | GO:0046899 | 2 | 2 | 16491 | 2452 |
AK4,AK3 |
| 2.210e-02 | -3.81 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity | molecular function | GO:0047322 | 2 | 2 | 16491 | 2452 |
PRKAA2,PRKAA1 |
| 2.210e-02 | -3.81 | sulfate adenylyltransferase (ATP) activity | molecular function | GO:0004781 | 2 | 2 | 16491 | 2452 |
PAPSS2,PAPSS1 |
| 2.210e-02 | -3.81 | alpha-(1,2)-fucosyltransferase activity | molecular function | GO:0031127 | 2 | 2 | 16491 | 2452 |
FUT2,FUT1 |
| 2.210e-02 | -3.81 | biliverdin reductase activity | molecular function | GO:0004074 | 2 | 2 | 16491 | 2452 |
BLVRA,BLVRB |
| 2.210e-02 | -3.81 | sterol-transporting ATPase activity | molecular function | GO:0034041 | 2 | 2 | 16491 | 2452 |
ABCG4,ABCG1 |
| 2.210e-02 | -3.81 | N-acylneuraminate cytidylyltransferase activity | molecular function | GO:0008781 | 2 | 2 | 16491 | 2452 |
CMAS,NANS |
| 2.210e-02 | -3.81 | methylcrotonoyl-CoA carboxylase activity | molecular function | GO:0004485 | 2 | 2 | 16491 | 2452 |
MCCC2,MCCC1 |
| 2.210e-02 | -3.81 | adenine transmembrane transporter activity | molecular function | GO:0015207 | 2 | 2 | 16491 | 2452 |
SLC25A4,SLC25A5 |
| 2.210e-02 | -3.81 | N-acetylgalactosamine-4-sulfatase activity | molecular function | GO:0003943 | 2 | 2 | 16491 | 2452 |
ARSB,GALNS |
| 2.210e-02 | -3.81 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding | molecular function | GO:0038049 | 2 | 2 | 16491 | 2452 |
NOTCH2,NR3C1 |
| 2.210e-02 | -3.81 | adenylylsulfate kinase activity | molecular function | GO:0004020 | 2 | 2 | 16491 | 2452 |
PAPSS2,PAPSS1 |
| 2.213e-02 | -3.81 | human chr7p21.1 | chromosome location | human chr7p21.1 | 16 | 5 | 26250 | 2805 |
TSPAN13,SNX13,ITGB8,MACC1,HDAC9 |
| 2.213e-02 | -3.81 | human chr6q14.1 | chromosome location | human chr6q14.1 | 16 | 5 | 26250 | 2805 |
SH3BGRL2,HMGN3,LCA5,IBTK,TMEM30A |
| 2.213e-02 | -3.81 | human chr8q22.3 | chromosome location | human chr8q22.3 | 16 | 5 | 26250 | 2805 |
CTHRC1,ATP6V1C1,GRHL2,BAALC-AS1,RIMS2 |
| 2.214e-02 | -3.81 | cytoskeleton-dependent intracellular transport | biological process | GO:0030705 | 106 | 24 | 16441 | 2455 |
KIF3C,SOD1,LCA5,UXT,KLC2,KIF1C,KIF13A,RAB6A,APBA1,IFT27,SSX2IP,MAP1B,TTC21B,KIF5B,HTT,KIF14,WDR19,TRAF3IP1,KLC3,SSNA1,NDE1,RPGR,RASGRP1,COPG1 |
| 2.216e-02 | -3.81 | monosaccharide binding | molecular function | GO:0048029 | 69 | 17 | 16491 | 2452 |
GALK1,UGP2,SLC2A8,P3H2,PYGL,M6PR,FUCA1,PLOD2,PFKL,LMAN2L,P4HA2,P4HA3,GYS1,PLOD3,EGLN3,LMAN1,EGLN1 |
| 2.219e-02 | -3.81 | uDENN | smart domains | SM00800 | 15 | 6 | 9131 | 1455 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 2.222e-02 | -3.81 | FAM134C (family with sequence similarity 134, member C) | protein interactions | 162427 | 41 | 12 | 16036 | 2547 |
PLSCR1,TSPAN15,CD63,ATP9A,GNPTAB,XYLT2,POMGNT1,NCAM1,TTYH3,KTN1,TSPAN17,GABARAPL1 |
| 2.223e-02 | -3.81 | V$HP1SITEFACTOR_Q6 | MSigDB lists | V$HP1SITEFACTOR_Q6 | 218 | 43 | 17758 | 2588 |
NCKAP5,HOXB7,ARFGEF1,ATP6V1E2,LMNA,HDAC9,MECOM,SCML1,PLS3,CTNNBIP1,TFAP4,FOXP2,CDKL5,DPYSL2,RGS3,TMEM62,GPC3,LMO4,BHLHE41,LHX6,STEAP2,BCL6,DUSP10,H2AFY,CITED2,TGIF1,PIK3R1,RGAG1,VAMP3,CALCRL,PRICKLE1,RAB3IP,CYFIP2,SFXN5,NFIX,PITX2,TMEM164,TAPBP,MPRIP,HOXA9,AXL,PPP1CB,LEMD1 |
| 2.225e-02 | -3.81 | positive regulation of cell division | biological process | GO:0051781 | 128 | 28 | 16441 | 2455 |
PLK1,PDGFC,NKX3-1,RHOA,DLGAP5,MACC1,CIT,RGCC,KIF23,RACGAP1,KIF20B,NUSAP1,AURKB,PDGFB,NPM2,PGF,PDGFA,MDK,RB1,INSR,IGF1R,FGFR2,PTEN,KIF14,CDCA5,AURKA,UBE2C,ESPL1 |
| 2.229e-02 | -3.80 | GSE12366_GC_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_GC_VS_MEMORY_BCELL_UP | 177 | 36 | 17758 | 2588 |
SPC25,ST14,SAP130,PLK4,UBE2J1,H2AFY,SGK1,CTTN,AK3,C12orf75,HSPA2,CCDC88A,METAP2,LOC81691,PSRC1,KIF20A,TACC1,PBK,SLC39A8,SYNE2,SYBU,CDC20,CDCA2,ROR1,ASB13,SLC25A5,RNF19B,FBXO10,PSMA4,SWAP70,MAP2,LRIG1,CDCA5,DBI,CD81,SNX30 |
| 2.229e-02 | -3.80 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | 177 | 36 | 17758 | 2588 |
BIN1,ZNF395,CKAP2,RASGRP3,TRIB2,ETS1,BARD1,FAM46C,CDK14,WEE1,ADD3,PAIP2B,CD22,PLCG2,DDHD2,TSPAN13,RASGRP1,SMAGP,SYPL1,SEPT6,EZR,EAF2,SAV1,CYFIP2,NCOA3,BTG1,BANK1,SWAP70,ITPR1,FAM3C,TLE1,PIK3C2B,TRAF5,SLC25A38,PKIA,DENND5B |
| 2.229e-02 | -3.80 | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP | 177 | 36 | 17758 | 2588 |
BIN1,SSH1,CAST,ARHGEF7,DGKA,IL27RA,TRMT2B,NOTCH2,SNN,DENND2D,PER2,NUP210,HSF2,RNF220,SP100,CNTRL,PAK2,AIM1,CAPG,FBXL14,BCL6,DIXDC1,PIK3CD,PIKFYVE,VPS11,PTPN18,RUNX3,SAV1,ABR,STK17A,CD83,FYN,DCK,RAB11FIP1,SERPINB1,PHC1 |
| 2.229e-02 | -3.80 | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 177 | 36 | 17758 | 2588 |
UBASH3B,C1orf198,HERC6,DPP8,DTX3L,ZFX,ENTPD4,SESN3,ELMO2,SLC16A6,AIM1,PIK3CA,FAM102A,MAST4,MYLIP,CKAP4,NAGPA,COQ10B,BTBD19,MGAM,TCF7,CD83,DCTN6,SCARB2,ZNF641,SERPINA1,RAB11FIP2,PLK2,PELI2,TADA2B,NR4A3,HS3ST3B1,RELL1,GEM,EPB41L4A,ATMIN |
| 2.229e-02 | -3.80 | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 177 | 36 | 17758 | 2588 |
RASA2,HEXB,TESK2,DHX8,SLC36A4,FTH1,MORF4L2,HLA-A,VPS26A,APPBP2,AKIRIN1,RBM23,SIPA1L2,SETDB2,CTNNB1,SRP54,SELK,HSPA13,MANF,WBP4,DVL2,MOB4,UFD1L,ACBD3,COQ10B,NPHP3,BCL2L13,ARF4,TRIM69,SPINT2,ITPR1,SPCS3,ST3GAL1,NDFIP1,RTN3,GOLGB1 |
| 2.229e-02 | -3.80 | HALLMARK_PEROXISOME | MSigDB lists | HALLMARK_PEROXISOME | 103 | 23 | 17758 | 2588 |
SOD1,PEX6,SOD2,VPS4B,CRABP2,DHRS3,IDH1,BCL10,TOP2A,IDE,PEX5,SLC25A4,PEX2,FABP6,MSH2,ABCB1,ECI2,ABCD1,HMGCL,ACSL4,SULT2B1,CTBP1,ISOC1 |
| 2.229e-02 | -3.80 | protein-pyridoxal-5-phosphate linkage | biological process | GO:0018352 | 2 | 2 | 16441 | 2455 |
GAD1,CTH |
| 2.229e-02 | -3.80 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis | biological process | GO:0060598 | 2 | 2 | 16441 | 2455 |
TFAP2C,AREG |
| 2.229e-02 | -3.80 | cellular response to redox state | biological process | GO:0071461 | 2 | 2 | 16441 | 2455 |
ARHGDIB,VASN |
| 2.229e-02 | -3.80 | positive regulation of centriole replication | biological process | GO:0046601 | 2 | 2 | 16441 | 2455 |
VPS4B,PLK4 |
| 2.229e-02 | -3.80 | negative regulation of neurotrophin production | biological process | GO:0032900 | 2 | 2 | 16441 | 2455 |
ADORA1,FURIN |
| 2.229e-02 | -3.80 | regulation of protein catabolic process in the vacuole | biological process | GO:1904350 | 2 | 2 | 16441 | 2455 |
RNF128,CD81 |
| 2.229e-02 | -3.80 | positive regulation of protein catabolic process in the vacuole | biological process | GO:1904352 | 2 | 2 | 16441 | 2455 |
RNF128,CD81 |
| 2.229e-02 | -3.80 | interleukin-27-mediated signaling pathway | biological process | GO:0070106 | 2 | 2 | 16441 | 2455 |
IL27RA,IL6ST |
| 2.229e-02 | -3.80 | resolution of recombination intermediates | biological process | GO:0071139 | 2 | 2 | 16441 | 2455 |
XRCC3,GEN1 |
| 2.229e-02 | -3.80 | cell-cell signaling involved in metanephros development | biological process | GO:0072204 | 2 | 2 | 16441 | 2455 |
GATA3,LGR4 |
| 2.229e-02 | -3.80 | vesicle targeting, trans-Golgi to endosome | biological process | GO:0048203 | 2 | 2 | 16441 | 2455 |
AP1AR,WIPI1 |
| 2.229e-02 | -3.80 | cell-cell signaling involved in kidney development | biological process | GO:0060995 | 2 | 2 | 16441 | 2455 |
GATA3,LGR4 |
| 2.229e-02 | -3.80 | nuclear migration along microfilament | biological process | GO:0031022 | 2 | 2 | 16441 | 2455 |
SUN2,SYNE2 |
| 2.229e-02 | -3.80 | metanephric smooth muscle tissue development | biological process | GO:0072208 | 2 | 2 | 16441 | 2455 |
PKD2,OSR1 |
| 2.229e-02 | -3.80 | establishment of anatomical structure orientation | biological process | GO:0048560 | 2 | 2 | 16441 | 2455 |
TTC8,IRX4 |
| 2.229e-02 | -3.80 | nucleotide-binding oligomerization domain containing 1 signaling pathway | biological process | GO:0070427 | 2 | 2 | 16441 | 2455 |
RIPK2,NFKBIA |
| 2.229e-02 | -3.80 | basal protein localization | biological process | GO:0045175 | 2 | 2 | 16441 | 2455 |
ERBB2IP,NCKAP1 |
| 2.229e-02 | -3.80 | regulation of MyD88-dependent toll-like receptor signaling pathway | biological process | GO:0034124 | 2 | 2 | 16441 | 2455 |
IRF7,IRF1 |
| 2.229e-02 | -3.80 | negative regulation of cyclic nucleotide catabolic process | biological process | GO:0030806 | 2 | 2 | 16441 | 2455 |
MAPK7,EGLN1 |
| 2.229e-02 | -3.80 | positive regulation of determination of dorsal identity | biological process | GO:2000017 | 2 | 2 | 16441 | 2455 |
ACVR1,CTNNB1 |
| 2.229e-02 | -3.80 | synaptonemal complex disassembly | biological process | GO:0070194 | 2 | 2 | 16441 | 2455 |
PLK1,HSPA2 |
| 2.229e-02 | -3.80 | protein deamination | biological process | GO:0018277 | 2 | 2 | 16441 | 2455 |
LOXL2,LOXL1 |
| 2.229e-02 | -3.80 | canonical Wnt signaling pathway involved in metanephric kidney development | biological process | GO:0061290 | 2 | 2 | 16441 | 2455 |
GATA3,LGR4 |
| 2.229e-02 | -3.80 | negative regulation of vascular smooth muscle contraction | biological process | GO:1904694 | 2 | 2 | 16441 | 2455 |
DOCK4,DOCK5 |
| 2.229e-02 | -3.80 | regulation of eIF2 alpha phosphorylation by heme | biological process | GO:0010999 | 2 | 2 | 16441 | 2455 |
FECH,EIF2AK1 |
| 2.229e-02 | -3.80 | kidney smooth muscle tissue development | biological process | GO:0072194 | 2 | 2 | 16441 | 2455 |
PKD2,OSR1 |
| 2.229e-02 | -3.80 | positive regulation of DNA endoreduplication | biological process | GO:0032877 | 2 | 2 | 16441 | 2455 |
E2F7,E2F8 |
| 2.229e-02 | -3.80 | regulation of cell motility involved in somitogenic axis elongation | biological process | GO:0090249 | 2 | 2 | 16441 | 2455 |
PPP2R3A,NKD1 |
| 2.229e-02 | -3.80 | negative regulation of oxidative phosphorylation uncoupler activity | biological process | GO:2000276 | 2 | 2 | 16441 | 2455 |
PPIF,TWIST1 |
| 2.229e-02 | -3.80 | negative regulation of phosphatidylinositol biosynthetic process | biological process | GO:0010512 | 2 | 2 | 16441 | 2455 |
PDGFA,PDGFB |
| 2.229e-02 | -3.80 | negative regulation of epithelial cell differentiation involved in kidney development | biological process | GO:2000697 | 2 | 2 | 16441 | 2455 |
OSR1,STAT1 |
| 2.229e-02 | -3.80 | resolution of mitotic recombination intermediates | biological process | GO:0071140 | 2 | 2 | 16441 | 2455 |
XRCC3,GEN1 |
| 2.229e-02 | -3.80 | regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter | biological process | GO:0072363 | 2 | 2 | 16441 | 2455 |
PPARA,TP53 |
| 2.229e-02 | -3.80 | female courtship behavior | biological process | GO:0008050 | 2 | 2 | 16441 | 2455 |
THRB,THRA |
| 2.229e-02 | -3.80 | activation of APC-Cdc20 complex activity | biological process | GO:0007092 | 2 | 2 | 16441 | 2455 |
PLK1,PTEN |
| 2.229e-02 | -3.80 | negative regulation of cAMP catabolic process | biological process | GO:0030821 | 2 | 2 | 16441 | 2455 |
MAPK7,EGLN1 |
| 2.229e-02 | -3.80 | negative regulation of integrin activation | biological process | GO:0033624 | 2 | 2 | 16441 | 2455 |
KIF14,PTGER4 |
| 2.229e-02 | -3.80 | positive regulation of ubiquitin protein ligase activity | biological process | GO:1904668 | 2 | 2 | 16441 | 2455 |
PLK1,PTEN |
| 2.229e-02 | -3.80 | pro-T cell differentiation | biological process | GO:0002572 | 2 | 2 | 16441 | 2455 |
GATA3,FLT3 |
| 2.229e-02 | -3.80 | Wnt signaling pathway involved in kidney development | biological process | GO:0061289 | 2 | 2 | 16441 | 2455 |
GATA3,LGR4 |
| 2.229e-02 | -3.80 | ectodermal cell fate commitment | biological process | GO:0001712 | 2 | 2 | 16441 | 2455 |
ETS2,ELF5 |
| 2.229e-02 | -3.80 | negative regulation of nephron tubule epithelial cell differentiation | biological process | GO:0072183 | 2 | 2 | 16441 | 2455 |
OSR1,STAT1 |
| 2.229e-02 | -3.80 | negative regulation of cardioblast differentiation | biological process | GO:0051892 | 2 | 2 | 16441 | 2455 |
PRICKLE1,WNT3A |
| 2.229e-02 | -3.80 | regulation of Fas signaling pathway | biological process | GO:1902044 | 2 | 2 | 16441 | 2455 |
SP100,TMBIM1 |
| 2.230e-02 | -3.80 | response to estrogen | biological process | GO:0043627 | 190 | 39 | 16441 | 2455 |
GRN,CASP3,TRIM24,NQO1,SERPINB9,GATA3,PDGFB,ETS1,CCND1,CALR,CCNA2,CA2,CTNNB1,CTGF,PTEN,BMP7,CST3,CDKN1B,IGFBP2,ASH2L,ARNT2,CITED2,DUSP1,CITED4,CASP9,EGFR,SOCS3,MMP15,PTGS2,RGS9,NCOA3,TIMP3,AREG,MAP2,AURKA,GPER1,ARSB,FOXA1,DRD1 |
| 2.234e-02 | -3.80 | REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | MSigDB lists | REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | 92 | 21 | 17758 | 2588 |
MAP3K3,CXXC5,RHOA,RIPK2,LITAF,CD40,SLC20A1,BCL10,CARD8,PLK2,TSPAN6,SECTM1,ZDHHC13,NOD2,SLC44A2,CANT1,TFG,NDFIP1,TRAF5,F2R,EEF1D |
| 2.237e-02 | -3.80 | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN | MSigDB lists | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN | 224 | 44 | 17758 | 2588 |
HECA,PPP1R12A,GCAT,CD63,GGA1,RPS6KA1,RACGAP1,PDGFB,CARD10,PSIP1,GNS,SH3BP1,IRF2,TMBIM6,HMGCL,ATP2B1,SMAGP,SUN2,CDKN2AIP,SMARCA2,MBP,TCEB2,TMEM43,KDELR3,SLC11A2,NKAIN1,GALNT7,RNF19B,NFIB,SEC14L2,DDX23,DCTN6,FUCA1,BTG1,TIMP3,CDK19,NAT1,PIAS2,NRG1,MAP3K5,CBX5,APOL2,RARG,ISOC1 |
| 2.246e-02 | -3.80 | ion homeostasis | biological process | GO:0050801 | 578 | 104 | 16441 | 2455 |
CCDC109B,TRIM24,IBTK,EPAS1,GRIK2,ATP2C2,HEXB,XIAP,P2RX7,FTH1,PRKACA,CACNB4,SLC8B1,BCAP31,SLC9A7,APLP2,ATP6V0B,PQLC2,SCNN1A,SLC46A1,PLCG2,ATP13A3,STEAP2,TRPC1,CNNM4,GOT1,STEAP3,RAB20,TMEM64,SLC39A10,F2R,CHP1,SIRT1,CLCN3,SOD1,CD55,ACO1,SLC11A2,ATP1B1,RAB38,CD40,TMTC2,ITPR3,ATP13A2,EDNRA,SFXN1,ENPP1,ATP1A1,WFS1,SLC9A6,ATP7B,INPP4B,F2RL1,SLC31A2,ABCA1,PRKAA2,HSP90B1,CALB2,PRKAA1,MTL5,ABCG2,SLC25A27,ATP6V1E2,XPR1,SLC9A2,NEO1,CALR,CA2,GATA2,SGK3,BAX,SGK1,TMBIM6,NPTN,TTPA,SLC12A2,ATP2B1,SLC37A1,MFI2,ERO1A,GRIN1,TTC7A,EIF2AK1,NUBP1,SFXN5,STEAP1,FECH,SWAP70,SLC4A4,HTT,ITPR1,SLC4A3,DGAT2,PKD2,GPER1,ATP1B3,MCUR1,ATP6V1C1,NDFIP1,JAK3,CYBRD1,ABCG1,DRD1,DMPK |
| 2.253e-02 | -3.79 | DURAND_STROMA_NS_UP | MSigDB lists | DURAND_STROMA_NS_UP | 154 | 32 | 17758 | 2588 |
MYL9,LMO7,FBLIM1,LFNG,GDF15,TMEM170B,TNFSF9,PRRG4,PARM1,RNF128,CTSC,LLGL2,RUNDC3B,SLC35B4,ATRNL1,ALDH7A1,ARNT2,RAB27B,F2R,EZR,TCF7,MAP3K6,FZD7,PRKAG2,RBM47,MFSD2A,ITPR1,FAM110C,SPRY4,OSR1,UNC5B,DMPK |
| 2.255e-02 | -3.79 | beta-amyloid binding | molecular function | GO:0001540 | 34 | 10 | 16491 | 2452 |
LDLRAP1,IDE,BACE1,CST3,FBXO2,CLSTN1,SORL1,APBA1,ITM2C,APBA2 |
| 2.256e-02 | -3.79 | oxidoreductase activity, oxidizing metal ions | molecular function | GO:0016722 | 16 | 6 | 16491 | 2452 |
CYB561,FTH1,STEAP3,STEAP1,CYBRD1,STEAP2 |
| 2.259e-02 | -3.79 | MEMBRANE_PART | MSigDB lists | MEMBRANE_PART | 1607 | 262 | 17758 | 2588 |
LAMP1,ACVR1,GRIK2,SLC25A13,SYTL4,SLC20A1,SLC9A7,GRM5,ZYX,TGFBR3,STIM1,SLC46A1,STEAP2,FUT1,CLDN4,TACSTD2,IL10RB,LAMP2,SGCE,ACVR1C,SNTB2,SLC17A5,SLC25A5,ENPP1,SLC25A4,GDE1,ATP7B,SLC31A2,F2RL1,NOTCH2,MERTK,TSPAN7,DOPEY2,ITGA3,LYPD3,NECAB3,SLC16A6,CD22,OPN3,SORL1,CD70,STT3B,CACNA1D,CNGA1,PIKFYVE,NCAM1,TMED2,NAGPA,PIGC,FADS2,QSOX1,MMD,MFI2,PTPRH,CALCRL,EPHA1,STX3,PTPRF,MMP15,IL1R1,GABRD,SCARB2,SLC4A4,ITPR1,SLC4A3,MPP2,OSMR,EFNA1,TRPC3,SLC2A4,ST14,CD82,PKP2,IL13RA1,AIFM2,APC2,FLT3,DDR1,KTN1,CD46,MUC16,CDH1,EPHB4,TSPAN1,FZD4,COG2,SLC11A2,ATP1B1,FZD7,STX10,DDOST,SHROOM3,SLC9A6,WFS1,AXL,HS3ST3B1,HSP90B1,MPZL1,MAN1A2,BACE1,FLOT1,CYB561,KCNC4,EFNB1,ICAM1,RND1,NEO1,ITGB8,MGAT1,KCNK5,GPC3,BAX,SLC44A2,ATP8B1,TMBIM6,ERBB3,SGCB,SLC16A5,TMX1,MPP1,VAMP3,GRIN1,SNTB1,AIF1L,GALNT3,CNTNAP1,PROM1,LDLRAP1,ACVRL1,RYK,ABCB1,FZD5,CD81,BCAM,EPHA4,SDC1,CACNB4,HTR1D,ABCD4,ENTPD4,TM9SF2,CTNNB1,IL6ST,LMAN2L,SLC44A1,ABCA2,DLG1,TRPC1,PXMP4,TRAM1,IL1RAP,MCTP1,CD55,EZR,ERP44,ROR1,PLEKHB1,EDNRA,HS6ST1,KCNMB4,KCNK1,DOLPP1,MADD,POMT1,CD99,FXYD3,ABCG2,SORBS3,B4GALT4,ICAM5,KCNN4,FXYD5,SLC12A2,CKAP4,ABCC1,KDELR1,PCDH1,PODXL2,RGMB,BCL2L13,STEAP1,EGFR,GNAS,INSR,ATP1B3,SHROOM2,DRD1,SORBS1,IL15,SLC2A8,P2RX7,IL27RA,SLC7A2,EMP2,EXT2,BCAP31,SYTL2,ATP6V0B,SMO,VAT1,RPN2,ECE1,NOTCH3,LMAN1,F2R,CLCN3,PTPRU,PTGER4,IGSF8,ERBB2IP,CD40,DAG1,TAPBP,PTPRJ,RTN4RL1,ATP1A1,MMP17,PTK7,SECTM1,PEX2,EFNA5,LIFR,ABCA1,GOLIM4,TRAPPC10,TSPAN15,CD63,MCTP2,SELL,GABRG2,TGFBR1,JAG2,SBF1,LBR,XPR1,FZD6,SLC9A2,M6PR,IL17RB,ADORA1,MAGEE1,TSPAN13,SYK,SLC35A1,ATP2B1,GCNT1,P2RX4,SYPL1,ADAM17,PLAUR,AMFR,BCAR1,BCL10,CD83,CASP7,SPINT2,PGRMC1,ARRB1,PKD2,ATP6V1C1,GOLGB1,CD33 |
| 2.260e-02 | -3.79 | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_UP | 183 | 37 | 17758 | 2588 |
ST13,DHPS,DGKA,PHF1,AIP,EPS8L2,TMEM63A,GNB5,CNTRL,PASK,SMYD5,ABCC1,EPHX1,SYPL1,CDKN2AIP,FBLN5,EZR,SRSF5,PRKRA,NPDC1,MFSD7,PLEKHB1,KDSR,LDLRAP1,ATP1A1,PAFAH1B3,INPP4B,CAB39,HMGA1,TTC9,AKIP1,RGS14,NDFIP1,TBC1D4,NR3C2,PKIA,FAM134B |
| 2.262e-02 | -3.79 | regulation of axon extension | biological process | GO:0030516 | 90 | 21 | 16441 | 2455 |
SEMA6B,PLXNA1,ILK,CDK5R1,MAP1B,CDKL5,SEMA4D,DPYSL2,LIMK1,MEGF8,DNM2,TNFRSF12A,NRG1,PLXND1,SEMA3G,CTTN,NTN1,WNT3A,SEMA3A,L1CAM,SEMA3B |
| 2.262e-02 | -3.79 | phosphatidylinositol biosynthetic process | biological process | GO:0006661 | 90 | 21 | 16441 | 2455 |
PIGC,MTM1,INPPL1,PLAUR,INPP5D,PIK3R1,CDIPT,PIGL,PGAP1,CDS1,PI4K2B,INPP5E,PTEN,OCRL,PLCG2,INPP4B,PIK3CA,SLC27A1,PIK3C2B,PIK3CD,PIKFYVE |
| 2.263e-02 | -3.79 | CHST8 (carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8) | protein interactions | 64377 | 32 | 10 | 16036 | 2547 |
RBM23,GALNT12,FRAS1,FAM3C,MRS2,CLSTN1,MOXD1,B3GALNT2,TXNDC11,TMED2 |
| 2.263e-02 | -3.79 | OGFOD1 (2-oxoglutarate and iron-dependent oxygenase domain containing 1) | protein interactions | 55239 | 32 | 10 | 16036 | 2547 |
STK26,GNPDA1,PRCP,PYGL,EZR,CAPNS1,AHCY,ISOC1,RAD23A,PDIA4 |
| 2.263e-02 | -3.79 | NCAM1 (neural cell adhesion molecule 1) | protein interactions | 4684 | 32 | 10 | 16036 | 2547 |
MDK,PLCG1,FYN,PPP1CA,NCAM1,L1CAM,SPTB,FAM134C,RHEB,EGFR |
| 2.263e-02 | -3.79 | ATP2B2 (ATPase, Ca++ transporting, plasma membrane 2) | protein interactions | 491 | 32 | 10 | 16036 | 2547 |
SNTA1,LGR4,LGALS8,DLG1,GGH,ERBB2IP,DLG3,SCARA3,SLC9A3R2,SDF4 |
| 2.266e-02 | -3.79 | Metabolism of serotonin | REACTOME pathways | R-HSA-380612 | 2 | 2 | 8202 | 1235 |
MAOA,ALDH2 |
| 2.266e-02 | -3.79 | Synthesis of PI | REACTOME pathways | R-HSA-1483226 | 2 | 2 | 8202 | 1235 |
CDIPT,CDS1 |
| 2.266e-02 | -3.79 | Serotonin clearance from the synaptic cleft | REACTOME pathways | R-HSA-380615 | 2 | 2 | 8202 | 1235 |
MAOA,ALDH2 |
| 2.266e-02 | -3.79 | Stimulation of the cell death response by PAK-2p34 | REACTOME pathways | R-HSA-211736 | 2 | 2 | 8202 | 1235 |
CASP3,PAK2 |
| 2.267e-02 | -3.79 | CBAH | pfam domains | PF02275 | 2 | 2 | 16629 | 2504 |
ASAH1,NAAA |
| 2.267e-02 | -3.79 | Ald_Xan_dh_C | pfam domains | PF01315 | 2 | 2 | 16629 | 2504 |
XDH,AOX1 |
| 2.267e-02 | -3.79 | Glyco_transf_11 | pfam domains | PF01531 | 2 | 2 | 16629 | 2504 |
FUT2,FUT1 |
| 2.267e-02 | -3.79 | Smg4_UPF3 | pfam domains | PF03467 | 2 | 2 | 16629 | 2504 |
UPF3B,UPF3A |
| 2.267e-02 | -3.79 | Fer2_2 | pfam domains | PF01799 | 2 | 2 | 16629 | 2504 |
XDH,AOX1 |
| 2.267e-02 | -3.79 | MDFI | pfam domains | PF15316 | 2 | 2 | 16629 | 2504 |
MDFIC,MDFI |
| 2.267e-02 | -3.79 | APS_kinase | pfam domains | PF01583 | 2 | 2 | 16629 | 2504 |
PAPSS2,PAPSS1 |
| 2.267e-02 | -3.79 | GNT-I | pfam domains | PF03071 | 2 | 2 | 16629 | 2504 |
POMGNT1,MGAT1 |
| 2.267e-02 | -3.79 | DBB | pfam domains | PF14545 | 2 | 2 | 16629 | 2504 |
BANK1,PIK3AP1 |
| 2.267e-02 | -3.79 | Xylo_C | pfam domains | PF12529 | 2 | 2 | 16629 | 2504 |
XYLT2,XYLT1 |
| 2.267e-02 | -3.79 | NAD_binding_4 | pfam domains | PF07993 | 2 | 2 | 16629 | 2504 |
FAR2,FAR1 |
| 2.267e-02 | -3.79 | Syntaphilin | pfam domains | PF15290 | 2 | 2 | 16629 | 2504 |
SYBU,SNPH |
| 2.267e-02 | -3.79 | Peptidase_C50 | pfam domains | PF03568 | 2 | 2 | 16629 | 2504 |
CFAP46,ESPL1 |
| 2.267e-02 | -3.79 | Sec2p | pfam domains | PF06428 | 2 | 2 | 16629 | 2504 |
RAB3IP,RAB3IL1 |
| 2.267e-02 | -3.79 | Prominin | pfam domains | PF05478 | 2 | 2 | 16629 | 2504 |
PROM1,PROM2 |
| 2.267e-02 | -3.79 | CKS | pfam domains | PF01111 | 2 | 2 | 16629 | 2504 |
CKS1B,CKS2 |
| 2.267e-02 | -3.79 | LEDGF | pfam domains | PF11467 | 2 | 2 | 16629 | 2504 |
HDGFRP2,PSIP1 |
| 2.267e-02 | -3.79 | DUF4927 | pfam domains | PF16279 | 2 | 2 | 16629 | 2504 |
NCOA3,NCOA2 |
| 2.267e-02 | -3.79 | FAD_binding_5 | pfam domains | PF00941 | 2 | 2 | 16629 | 2504 |
XDH,AOX1 |
| 2.267e-02 | -3.79 | CKAP2_C | pfam domains | PF15297 | 2 | 2 | 16629 | 2504 |
CKAP2L,CKAP2 |
| 2.267e-02 | -3.79 | XTBD | pfam domains | PF11952 | 2 | 2 | 16629 | 2504 |
CDKN2AIP,CDKN2AIPNL |
| 2.267e-02 | -3.79 | Polyketide_cyc | pfam domains | PF03364 | 2 | 2 | 16629 | 2504 |
COQ10A,COQ10B |
| 2.267e-02 | -3.79 | NAAA-beta | pfam domains | PF15508 | 2 | 2 | 16629 | 2504 |
ASAH1,NAAA |
| 2.267e-02 | -3.79 | Rab_eff_C | pfam domains | PF04698 | 2 | 2 | 16629 | 2504 |
MLPH,MYRIP |
| 2.267e-02 | -3.79 | Isochorismatase | pfam domains | PF00857 | 2 | 2 | 16629 | 2504 |
ISOC2,ISOC1 |
| 2.267e-02 | -3.79 | MOR2-PAG1_C | pfam domains | PF14225 | 2 | 2 | 16629 | 2504 |
FRY,FRYL |
| 2.267e-02 | -3.79 | PUA_2 | pfam domains | PF14306 | 2 | 2 | 16629 | 2504 |
PAPSS2,PAPSS1 |
| 2.267e-02 | -3.79 | Rb_C | pfam domains | PF08934 | 2 | 2 | 16629 | 2504 |
RB1,RBL1 |
| 2.267e-02 | -3.79 | DUF3350 | pfam domains | PF11830 | 2 | 2 | 16629 | 2504 |
TBC1D4,TBC1D1 |
| 2.267e-02 | -3.79 | DUF4757 | pfam domains | PF15949 | 2 | 2 | 16629 | 2504 |
LMO7,LIMCH1 |
| 2.267e-02 | -3.79 | AdenylateSensor | pfam domains | PF16579 | 2 | 2 | 16629 | 2504 |
PRKAA2,PRKAA1 |
| 2.267e-02 | -3.79 | Melibiase_2 | pfam domains | PF16499 | 2 | 2 | 16629 | 2504 |
GLA,NAGA |
| 2.267e-02 | -3.79 | Sterile | pfam domains | PF03015 | 2 | 2 | 16629 | 2504 |
FAR2,FAR1 |
| 2.267e-02 | -3.79 | CO_deh_flav_C | pfam domains | PF03450 | 2 | 2 | 16629 | 2504 |
XDH,AOX1 |
| 2.267e-02 | -3.79 | Flot | pfam domains | PF15975 | 2 | 2 | 16629 | 2504 |
FLOT2,FLOT1 |
| 2.267e-02 | -3.79 | CCDC74_C | pfam domains | PF14917 | 2 | 2 | 16629 | 2504 |
CCDC74B,CCDC74A |
| 2.267e-02 | -3.79 | PRT_C | pfam domains | PF08372 | 2 | 2 | 16629 | 2504 |
MCTP1,MCTP2 |
| 2.267e-02 | -3.79 | IL17R_fnIII_D1 | pfam domains | PF16556 | 2 | 2 | 16629 | 2504 |
IL17RA,IL17RB |
| 2.267e-02 | -3.79 | MOR2-PAG1_N | pfam domains | PF14222 | 2 | 2 | 16629 | 2504 |
FRY,FRYL |
| 2.267e-02 | -3.79 | ATP-sulfurylase | pfam domains | PF01747 | 2 | 2 | 16629 | 2504 |
PAPSS2,PAPSS1 |
| 2.267e-02 | -3.79 | Ald_Xan_dh_C2 | pfam domains | PF02738 | 2 | 2 | 16629 | 2504 |
XDH,AOX1 |
| 2.267e-02 | -3.79 | DUF3480 | pfam domains | PF11979 | 2 | 2 | 16629 | 2504 |
ZFYVE16,ZFYVE9 |
| 2.267e-02 | -3.79 | PDGF_N | pfam domains | PF04692 | 2 | 2 | 16629 | 2504 |
PDGFA,PDGFB |
| 2.267e-02 | -3.79 | MOR2-PAG1_mid | pfam domains | PF14228 | 2 | 2 | 16629 | 2504 |
FRY,FRYL |
| 2.268e-02 | -3.79 | oligodendroglioma_Grade_II | COSMIC cancer mutations | oligodendroglioma_Grade_II | 76 | 18 | 17775 | 2585 |
AKT1,RET,PIK3R1,TP53,TEP1,ERBB2,PLXNA1,IDH1,GNA11,EGFR,GNAS,CDKN2C,RB1,MUC16,CTNNB1,PTEN,PIK3CA,AKNA |
| 2.272e-02 | -3.78 | SH2 | pfam domains | PF00017 | 100 | 23 | 16629 | 2504 |
INPPL1,INPP5D,STAT4,PIK3R1,TNS1,TEC,YES1,RASA1,SH2D4A,SOCS3,TXK,BCAR3,TNS4,PLCG1,TNS3,FYN,SHC3,STAT6,SH2D3C,PLCG2,STAT1,SYK,SOCS5 |
| 2.273e-02 | -3.78 | BRUINS_UVC_RESPONSE_EARLY_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_EARLY_LATE | 296 | 56 | 17758 | 2588 |
CCNE2,ANXA3,ACVR1,SORBS1,FAF2,FRMD4A,TUBB4B,GRIK2,TRAF2,CAMKK1,ACTR8,CTDSPL,EPHA4,ETV5,PKP2,CALM3,NENF,IFT27,CYP26A1,HDAC9,CALM2,SS18,IGF1R,CALD1,SIVA1,SLC30A6,USP38,DLG3,GFI1,SNX10,SPRY2,NR2C1,NEB,EBAG9,MOB4,DENND1B,CALM1,CDYL,RAB3IP,SPTLC2,SOCS3,BCAR3,AHRR,CAMK2N2,PVRL2,RND3,MAP2,CCDC6,PTER,LRIG1,PRDM5,NUP37,USF2,PPP2R2D,TMEM173,ZC3HC1 |
| 2.273e-02 | -3.78 | axon terminus | cellular component | GO:0043679 | 108 | 24 | 17570 | 2579 |
P2RX4,CLCN3,GRIK2,SEPT6,CALB2,EPHA4,GRIN1,SYP,ELK1,ILK,TANC1,KCNC4,ADORA1,SYT7,FLRT3,SLC9A6,DPYSL2,CPLX1,GOT1,GPER1,PACSIN1,L1CAM,DRD1,HCN3 |
| 2.274e-02 | -3.78 | V$PAX4_01 | MSigDB lists | V$PAX4_01 | 248 | 48 | 17758 | 2588 |
CCNI,NF2,DNAJB2,KLC2,ETV5,PDGFB,GNB2,PSIP1,H1FX,PER2,SAP130,TFAP4,ITGB8,CDK16,NECAB3,MEGF8,RANBP1,TRIM3,HEXIM2,PIK3CD,ACOX2,PDE4D,CACNA1D,DLG3,SPRY2,TMED2,SEMA3B,HES1,PHF20L1,TAF5,AMFR,CBX6,RNF19B,PNKD,SP4,LEMD2,PGF,CAMK2N2,NFKBIA,C1orf21,NR4A3,E2F1,EFNA5,TMEM8B,ARF6,JARID2,CTDSP1,FGD1 |
| 2.274e-02 | -3.78 | V$PEA3_Q6 | MSigDB lists | V$PEA3_Q6 | 248 | 48 | 17758 | 2588 |
ELK4,UNC93B1,CMAS,INPPL1,PAX6,ZCCHC24,SLC41A1,GATA3,SELL,IL18,CAMK1D,ITPR2,DENND2D,DUSP5,CDKN2C,ZNF687,ADRBK1,CYR61,FAM63A,SORL1,NCAM1,ZRANB1,GFI1,ZNF365,VPS11,TAF5,TRIM8,MARK1,KIAA0040,SLC35C1,VWA1,NKAIN1,ARHGDIB,RUNX3,CBL,PDIK1L,TYSND1,ATP13A2,DDX23,FUCA1,MAPKAPK2,CRTC2,NT5C2,ARAP1,PGM2L1,RNASEL,NRGN,RTN3 |
| 2.281e-02 | -3.78 | bone-chondrosarcoma | COSMIC cancer mutations | bone-chondrosarcoma | 109 | 24 | 17775 | 2585 |
SUN1,HPS3,AKT1,TBC1D8B,AASS,MGAT4B,TP53,ERBB2,IDH1,PTGFRN,KCNC4,EGFR,GNAS,ZYX,RB1,KIAA0895,CTNNB1,PTEN,PIK3CA,SH3BP4,SMO,FHL1,TRPC3,ABCG1 |
| 2.283e-02 | -3.78 | ION_BINDING | MSigDB lists | ION_BINDING | 266 | 51 | 17758 | 2588 |
DYRK3,PINK1,HSP90B1,REPS2,SLC25A13,MCTP2,MTL5,TP53,CALM3,NUCB2,HPCAL4,NCS1,CALM2,CALR,RCN1,CA2,STIM1,CABP1,MSH2,PIM1,S100A13,APOBEC3G,RASGRP1,ERAP2,MSH6,GCA,SOD1,MCTP1,KCNIP3,MARK1,FIGNL1,GCLC,S100A4,RNF11,CRIP2,CALM1,CDA,PIF1,MAP3K6,CDK5R1,FECH,MMP15,MMP17,STK38,ATP7B,PIAS2,PKD2,MAP3K5,LTA4H,KLF7,MAPK12 |
| 2.285e-02 | -3.78 | YAGI_AML_SURVIVAL | MSigDB lists | YAGI_AML_SURVIVAL | 120 | 26 | 17758 | 2588 |
VPS11,ADAM17,PEX6,CORO2A,STAU2,TRAF2,NPC2,LEPR,LBR,SLC9A7,APPBP2,APOBEC3B,APLP2,ATP6V0B,ENPP1,INPP5E,TYMP,ZYX,VASP,SLC25A4,NFKBIA,DDHD2,GTF2F2,VAT1,TTPA,CLIP2 |
| 2.286e-02 | -3.78 | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP | MSigDB lists | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP | 60 | 15 | 17758 | 2588 |
FUCA1,PTGS2,MCTP1,RIPK2,ETS2,WIPI1,SLC16A6,PLAUR,SOD2,RAB20,CHPT1,GM2A,RHOB,IER3,PRKAR1A |
| 2.286e-02 | -3.78 | SONG_TARGETS_OF_IE86_CMV_PROTEIN | MSigDB lists | SONG_TARGETS_OF_IE86_CMV_PROTEIN | 60 | 15 | 17758 | 2588 |
CASP3,BTG3,PCNA,ZWINT,FOXM1,DCK,PTTG1,MYBL2,MSH2,E2F1,POLD3,KIF11,BARD1,CDK1,DDX23 |
| 2.286e-02 | -3.78 | YAATNANRNNNCAG_UNKNOWN | MSigDB lists | YAATNANRNNNCAG_UNKNOWN | 60 | 15 | 17758 | 2588 |
GNAS,FOXP2,PGM1,CD55,PQLC2,IRAK1,FGFR2,CALD1,STRN4,IRX4,NUSAP1,RFX5,RAG1,LDB2,SPTB |
| 2.289e-02 | -3.78 | GSE27786_LSK_VS_NKTCELL_UP | MSigDB lists | GSE27786_LSK_VS_NKTCELL_UP | 189 | 38 | 17758 | 2588 |
UNC93B1,FLYWCH2,SLC25A13,KCTD12,TEX2,ERP29,MESDC2,CCNA2,METTL7A,CAPG,BRI3,PHKA2,PTPRE,DGKG,MCCC2,PLK1,HMMR,SYPL1,MCTP1,ADCK3,LRRC66,CCBL2,CDCA2,TRIM35,RNF113A,ZFAND5,ATP13A2,PRDX4,TRIM47,PEX5,MATN2,MYLK,MAOA,AURKA,ACADM,MLKL,CMPK2,COL16A1 |
| 2.289e-02 | -3.78 | GSE3982_EOSINOPHIL_VS_MAC_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAC_DN | 189 | 38 | 17758 | 2588 |
CCNC,CMAS,MPZL1,GALNT12,CAST,KIF23,BLCAP,IL27RA,ISOC2,DHRS3,TAF1B,TACC2,H2AFY,VAT1,MANF,EPHX1,UPF3A,HMMR,TIMP2,ASPM,PLEKHO1,SLC11A2,PRRC1,IDH1,RNPEP,ALCAM,RHEB,OPTN,ATP13A2,CASP7,DNM1L,TIMM8A,PLA2G15,IARS2,OTUB2,PIK3C2B,PDXK,ITGAV |
| 2.289e-02 | -3.78 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | 189 | 38 | 17758 | 2588 |
TRIM5,MCOLN3,SOD2,DGKA,ADCK5,CTSZ,FAM78A,IL27RA,GRK6,TRIB2,FAM101B,SDF4,SESN3,TACC2,CD9,FAM102A,RAB20,TSPAN13,PACSIN1,DDB2,SLC11A2,MCFD2,RNF19B,SESN1,CASP4,CYB5A,KDSR,SCARB2,NEIL1,WDR11,FAAH,SPINT2,NR4A3,TTC39C,TRAF5,JAK3,FAM134B,ABCG1 |
| 2.289e-02 | -3.78 | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDM_DN | 189 | 38 | 17758 | 2588 |
KIF3C,HSP90B1,ARMCX3,IL15RA,RUSC2,MAN1A2,SLC41A1,ITPR2,DPP8,APPBP2,ZFYVE16,SUSD2,BTG3,VASP,TAF1B,ARL1,KLF3,SLC44A1,IL17RA,MDFIC,ADAM17,NR3C1,PLAUR,AMFR,RNF11,CALCRL,PIM3,ATP1B1,SAV1,ABR,RGS9,PI4K2B,RND3,CSF1,NFKBIA,ITGAV,IFIH1,IRF1 |
| 2.289e-02 | -3.78 | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 189 | 38 | 17758 | 2588 |
NFKBIE,GGA1,TMEM41B,APOO,SOD2,DNAJB11,SLC36A4,DUSP5,CXCL16,SH3D21,P4HB,ATP13A3,HSPA13,PDE4D,TFG,TIPARP,C9orf72,CTNNAL1,PLAUR,RAPGEF2,EMP3,TXNDC11,ARF4,FRMD4B,CD83,CNOT2,MAPKAPK2,ATP1A1,NFKBIA,MADD,SIPA1L1,HMGA1,ATP6V1C1,ZMIZ1,CBX5,PTGES,MAFF,SNPH |
| 2.289e-02 | -3.78 | GSE27786_CD4_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_CD4_VS_CD8_TCELL_UP | 189 | 38 | 17758 | 2588 |
GAS2L1,WASF3,FBLIM1,PTTG1,EPHX4,P2RX7,TEX2,FBXO6,NUCB2,APBA1,MAP1LC3B,CDKN2C,ACAP2,IGF1R,GNB5,FRYL,CCDC82,TNFRSF18,TSPAN13,TIAM1,CTDSP2,ATP2B1,MYO5A,GPX4,ZNF462,GCA,PLSCR1,CORO2A,ZBTB7B,CASP4,H1F0,MAP2,FAAH,SLC9A6,ITGAV,ARPC2,TMEM173,ESYT2 |
| 2.289e-02 | -3.78 | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 189 | 38 | 17758 | 2588 |
SORT1,PACSIN2,ARAP3,FRMD4A,SAMD9,BMP2K,MXD1,HLA-A,SIRPA,UHRF1BP1L,DAPK2,ZYX,RALB,PAK2,GALNS,BCL6,UBE2J1,OSTF1,PTPRE,CERS2,XKR8,DOCK4,PLSCR1,CDA,ERP44,SRSF5,POR,KLHL2,SLC6A6,STX10,PRCP,RAP2C,SECTM1,PPP1CB,CANT1,DYSF,IRF1,RRAGD |
| 2.289e-02 | -3.78 | GSE17721_PAM3CSK4_VS_CPG_8H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_8H_BMDM_DN | 189 | 38 | 17758 | 2588 |
UNC93B1,ARHGEF3,ARMCX3,CPEB4,TRIP10,PARP14,HLA-E,NDRG1,ESRP1,DGKA,DNAJB11,GALM,MXD1,FOSB,ARVCF,SGK1,TFG,PSMA5,MYO5A,DUSP1,PVRL4,ENPP4,SIRT1,TGIF1,RIPK2,ALCAM,FOS,NMT2,ARF4,HLA-B,NAT1,UBE2D2,SH3BP4,CHMP4B,GLA,PLOD3,ST3GAL1,STARD3NL |
| 2.289e-02 | -3.78 | GSE27786_LIN_NEG_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_CD8_TCELL_UP | 189 | 38 | 17758 | 2588 |
LZTFL1,SORT1,CUL1,SYTL4,FLT3,MAGOHB,ELMO2,P4HB,SMO,ZDHHC13,VAT1,AK3,PIK3CD,EGLN3,SLC45A3,TMEM9,KCTD3,GCNT1,METAP2,P2RX4,ATL1,ZWINT,CRIP2,AK4,CCDC34,CDCA2,CCNF,PI4K2B,NUCB1,H1F0,PRCP,ZFP30,AMMECR1,DBI,DTX4,DMWD,AKIP1,DLAT |
| 2.289e-02 | -3.78 | CHANDRAN_METASTASIS_UP | MSigDB lists | CHANDRAN_METASTASIS_UP | 189 | 38 | 17758 | 2588 |
ADD1,ZNF395,CPEB4,IBTK,FOXM1,DNAJC3,DCAF7,UBE2Z,GPR180,PLXNA1,MORF4L2,INTS8,TIPRL,KIAA1147,MAGOHB,ZFYVE16,SPP1,DAZAP1,WDFY1,TRIM3,CDKN2D,FGFR1OP2,ATG4D,MYO5B,ADAM17,RIPK2,BTNL9,NUB1,AK4,PRRC1,GOLT1A,HS6ST1,SLC35B3,ITPR1,CDK18,DONSON,CBX5,CBX4 |
| 2.289e-02 | -3.78 | GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP | MSigDB lists | GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP | 189 | 38 | 17758 | 2588 |
RMND5A,CMAS,HJURP,IBTK,MRPS15,MCTP2,C11orf95,CENPN,PSMD1,HSF2,TAF1B,FAM189A1,SLC16A6,PLCG2,SRR,RP2,NPTN,CASD1,TMED2,GFPT1,SOAT1,TBC1D8B,SEPT6,MRS2,RNF11,TFAP2C,VEZT,PLS1,GALNT7,KIF11,RANBP9,BCL10,DCAF10,PPP2R5A,STK39,TOB1,TMEM131,EGLN1 |
| 2.290e-02 | -3.78 | TP53BP2 (tumor protein p53 binding protein 2) | protein interactions | 7159 | 90 | 22 | 16036 | 2547 |
AMOTL2,PLK1,PPP1R2,FRMD6,ITCH,RASSF7,NDC80,TP53,YES1,BCL2L1,SSX2IP,WWP2,CCDC92,RASSF8,LMO4,WWTR1,DCUN1D1,E2F1,PPP1CB,OTUB2,WWP1,PPP1CA |
| 2.300e-02 | -3.77 | positive regulation of phosphoprotein phosphatase activity | biological process | GO:0032516 | 16 | 6 | 16441 | 2455 |
CALM3,CALM2,SLC39A10,PPP1R12A,CALM1,PPP2R4 |
| 2.300e-02 | -3.77 | striatum development | biological process | GO:0021756 | 16 | 6 | 16441 | 2455 |
FOXP2,CNTNAP2,BBS2,HTT,ALDH1A3,DRD1 |
| 2.300e-02 | -3.77 | regulation of synaptic transmission, dopaminergic | biological process | GO:0032225 | 16 | 6 | 16441 | 2455 |
PTGS2,PINK1,RAB3B,PNKD,FLOT1,DRD1 |
| 2.300e-02 | -3.77 | negative regulation of lipid storage | biological process | GO:0010888 | 16 | 6 | 16441 | 2455 |
ITGAV,ABCA1,PNPLA2,NFKBIA,ABCG1,PPARA |
| 2.301e-02 | -3.77 | nerve development | biological process | GO:0021675 | 69 | 17 | 16441 | 2455 |
HES1,SERPINE2,RET,SLC1A3,ILK,HOXB2,DAG1,SIX4,NRP2,TBX1,LRIG1,CTSV,TFAP2A,ATP8B1,ERBB3,SEMA3A,SULF2 |
| 2.302e-02 | -3.77 | PAS | smart domains | SM00091 | 32 | 10 | 9131 | 1455 |
AHRR,NCOA3,EPAS1,PASK,ARNT2,PER3,AHR,ARNT,NCOA2,PER2 |
| 2.302e-02 | -3.77 | PDPK1 (3-phosphoinositide dependent protein kinase 1) | protein interactions | 5170 | 70 | 18 | 16036 | 2547 |
FAM213B,PRSS23,AKT1,FAM199X,RPS6KA1,PRKCQ,PKN1,SBF1,ILK,PRKACA,SLC9A3R2,SOCS3,PRKCI,SGK3,SGK1,CDAN1,ZC3HC1,RPS6KA3 |
| 2.304e-02 | -3.77 | intronic transcription regulatory region DNA binding | molecular function | GO:0044213 | 12 | 5 | 16491 | 2452 |
HSF2,GRHL2,THRA,NCOA2,BCL6 |
| 2.304e-02 | -3.77 | guanylate kinase activity | molecular function | GO:0004385 | 12 | 5 | 16491 | 2452 |
CASK,DLG3,MPP1,DLG1,MPP2 |
| 2.305e-02 | -3.77 | DBB | prosite domains | PS51376 | 2 | 2 | 11866 | 1802 |
BANK1,PIK3AP1 |
| 2.305e-02 | -3.77 | CKS_1 | prosite domains | PS00944 | 2 | 2 | 11866 | 1802 |
CKS1B,CKS2 |
| 2.305e-02 | -3.77 | GLYCOSYL_HYDROL_F35 | prosite domains | PS01182 | 2 | 2 | 11866 | 1802 |
GLB1,GLB1L2 |
| 2.305e-02 | -3.77 | ALPHA_GALACTOSIDASE | prosite domains | PS00512 | 2 | 2 | 11866 | 1802 |
GLA,NAGA |
| 2.305e-02 | -3.77 | CKS_2 | prosite domains | PS00945 | 2 | 2 | 11866 | 1802 |
CKS1B,CKS2 |
| 2.305e-02 | -3.77 | CDS | prosite domains | PS01315 | 2 | 2 | 11866 | 1802 |
CDS2,CDS1 |
| 2.306e-02 | -3.77 | TUBA1C (tubulin, alpha 1c) | protein interactions | 84790 | 85 | 21 | 16036 | 2547 |
NF2,TUBB4B,DSTN,CUL4B,CDC20,TP53,FLOT1,CUL1,AURKB,FBXO6,HDAC6,CBL,LGALS3BP,VCP,MAGED2,DCUN1D1,TUBG1,AURKA,ARRB1,CD81,TUBA4A |
| 2.313e-02 | -3.77 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE | 76 | 18 | 17758 | 2588 |
TIMP2,AGRN,CTSB,SDC4,CLSTN1,COL18A1,NPC2,SDC1,PSMA4,LGALS3BP,CDH1,CST3,CANT1,GOT1,CTSA,MDH1,CTSD,CD81 |
| 2.313e-02 | -3.77 | MODULE_213 | MSigDB lists | MODULE_213 | 76 | 18 | 17758 | 2588 |
SHMT1,FXYD3,DCAF7,SEPT6,DGKA,GRIN1,SLC11A2,PRKCQ,CCNF,MAN2A2,RAC2,DGCR2,NAB2,NRG1,EFNA1,APBA2,TOB1,EPHX1 |
| 2.313e-02 | -3.77 | MODULE_357 | MSigDB lists | MODULE_357 | 76 | 18 | 17758 | 2588 |
KLK10,KLK5,LMTK3,KLHL13,FXYD3,ITGA6,COL7A1,PPP1R14C,S100A2,EFNB1,PTGS2,CA2,AREG,ALDH1A3,SERPINB5,MAOA,CDH3,F2RL1 |
| 2.314e-02 | -3.77 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN | 195 | 39 | 17758 | 2588 |
MRC2,ST14,RPS6KA1,HLA-E,INPP5D,XYLT1,TMX4,AES,BLCAP,TRAPPC8,SEPP1,GSTP1,ERP29,PCNA,NUP210,MDFIC,ALDH3A2,PPP6R1,ATP2B1,TACC1,DRAP1,MRS2,KDELR3,UBAC1,FYN,ALDH5A1,DGCR2,RCBTB2,UTP14C,PSMD3,TRAF3IP1,MAP3K5,ARHGAP4,ZMIZ1,ARF6,RPL22,USF2,CBX7,TMEM131 |
| 2.314e-02 | -3.77 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP | 195 | 39 | 17758 | 2588 |
IBTK,TSC22D3,FAM134A,PDIA3,TESK2,CTSZ,EGR3,DUSP5,PDIA4,TYMP,VASP,P4HB,ZFP36,PAK2,FOSB,BCL6,SGK1,NPTN,CTSD,NFKB2,CKAP4,DUSP1,PPIF,QSOX1,GUSB,SAT1,MGAM,RNF19B,SOCS3,CD83,IL1R1,UAP1,AREG,HNRNPH2,NFKBIA,NR4A2,ARF6,RTN3,SRSF9 |
| 2.315e-02 | -3.77 | RANKL/RANK Signaling Pathway | WikiPathways | WP2018 | 54 | 15 | 4455 | 729 |
PLCG1,AKT1,PAPSS2,TRAF2,NFKBIA,MITF,PIK3R1,FHL2,NFKB2,CBL,MAP3K7,FOS,TRAF5,SYK,ICAM1 |
| 2.317e-02 | -3.76 | human chr4q31.1 | chromosome location | human chr4q31.1 | 11 | 4 | 26250 | 2805 |
GALNT7,SCOC,NR3C2,ELMOD2 |
| 2.317e-02 | -3.76 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological process | GO:0070059 | 34 | 10 | 16441 | 2455 |
DNAJC10,TRAF2,ITPR1,ERO1A,BAX,TMBIM6,DAB2IP,SELK,MAP3K5,CASP4 |
| 2.317e-02 | -3.76 | cytoplasmic pattern recognition receptor signaling pathway | biological process | GO:0002753 | 34 | 10 | 16441 | 2455 |
DDX58,RIPK2,IRAK1,TAB3,ITCH,NFKBIA,NOD2,IRF7,MAP3K7,IFIH1 |
| 2.317e-02 | -3.76 | embryonic forelimb morphogenesis | biological process | GO:0035115 | 34 | 10 | 16441 | 2455 |
RUNX2,CTNNB1,HOXA9,TFAP2A,TWIST1,OSR2,OSR1,CRABP2,SHOX2,MECOM |
| 2.317e-02 | -3.76 | establishment of spindle localization | biological process | GO:0051293 | 34 | 10 | 16441 | 2455 |
CENPA,HTT,LLGL2,NDC80,NUSAP1,GPSM2,SPDL1,NDE1,SPRY2,ESPL1 |
| 2.317e-02 | -3.76 | regulation of rhodopsin mediated signaling pathway | biological process | GO:0022400 | 34 | 10 | 16441 | 2455 |
CALM2,RGS9,FNTA,GNB5,CALM1,CALM3,PRKCQ,CNGA1,NMT2,METAP2 |
| 2.322e-02 | -3.76 | positive regulation of neuron projection development | biological process | GO:0010976 | 202 | 41 | 16441 | 2455 |
GRN,FOXO6,SERPINE2,RET,EPHA4,CAMK1D,CRABP2,ITGA3,CDKL5,MEGF8,BMP7,PRKCI,TNFRSF12A,DAB2IP,NPTN,PACSIN1,WNT3A,NTN1,TIAM1,RIMS2,FAM134C,RHOA,RAPGEF2,ILK,MAP1B,ARHGAP35,DPYSL3,FYN,GPRC5B,SEMA4D,BHLHB9,TMEM30A,LIMK1,PTK7,NRG1,EFNA5,ITPKA,ARSB,SHOX2,L1CAM,COBL |
| 2.324e-02 | -3.76 | chemical homeostasis | biological process | GO:0048878 | 882 | 153 | 16441 | 2455 |
TRIM24,IBTK,EPAS1,GRIK2,HEXB,XIAP,TAP1,CACNB4,SLC8B1,SLC9A7,SESN3,PQLC2,SLC46A1,ATP13A3,STEAP2,PIK3CA,ABCA2,CLDN4,TRPC1,CRY2,RAB20,ACOX2,SLC39A10,SOD1,CD55,PRKAR2B,EDNRA,SFXN1,ENPP1,GPRC5B,ATP7B,ADIPOR1,F2RL1,SLC31A2,PRKAA2,DHPS,CALB2,PRKAA1,MTL5,ABCG2,SLC25A27,ATP6V1E2,CALR,CA2,GATA2,NPTN,ACAD8,MYLIP,SLC12A2,SLC37A1,MFI2,ERO1A,PYGL,EIF2AK1,NPC2,PDK3,NUBP1,SFXN5,STEAP1,FECH,GNAS,IL1R1,INSR,SLC4A4,HTT,ITPR1,SLC4A3,DGAT2,ATP1B3,JAK3,DRD1,EGLN1,EHD1,DMPK,SLC2A4,PAX6,CCDC109B,ATP2C2,SOD2,WDTC1,P2RX7,PKP2,FTH1,PRKACA,BCAP31,ATP6V0B,APLP2,SCNN1A,PLCG2,CNNM4,STEAP3,GOT1,TMEM64,IFIT1,MYT1,F2R,CHP1,MYO5B,SIRT1,SOAT1,CLCN3,AKT1,ACO1,SLC11A2,RAB38,ATP1B1,ITPR3,TMTC2,CD40,ATP13A2,IRS2,ATP1A1,ACAD10,SLC9A6,WFS1,PEX2,INPP4B,STAT1,ABCA1,PRKAR1A,HSP90B1,GSTP1,SLC9A2,XPR1,ICAM1,NEO1,BAX,SGK3,SGK1,TMBIM6,TTPA,ATP2B1,EIF5A2,PIK3R1,GRIN1,TTC7A,CRTC2,LDLRAP1,SWAP70,ACADSB,NR1D2,RAB11FIP2,PRCP,PKD2,MCUR1,ACADM,GPER1,ATP6V1C1,USF2,NDFIP1,CYBRD1,FOXA1,ABCG1 |
| 2.332e-02 | -3.76 | GNF2_PRDX2 | MSigDB lists | GNF2_PRDX2 | 30 | 9 | 17758 | 2588 |
GCLM,ANK1,CA2,HEBP1,AMMECR1,BLVRB,UBAC1,MINPP1,SPTB |
| 2.332e-02 | -3.76 | MODULE_221 | MSigDB lists | MODULE_221 | 30 | 9 | 17758 | 2588 |
PCCB,ALDH2,ALDH6A1,ACADSB,CPT2,BLVRB,ACOX2,ACADM,ALDH3A2 |
| 2.332e-02 | -3.76 | VIRAL_INFECTIOUS_CYCLE | MSigDB lists | VIRAL_INFECTIOUS_CYCLE | 30 | 9 | 17758 | 2588 |
TOP2A,TNIP1,ITCH,WWP1,MDFIC,CD81,CTBP1,APOBEC3G,WWP2 |
| 2.332e-02 | -3.76 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_OLD | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_OLD | 30 | 9 | 17758 | 2588 |
PRSS23,ITGB8,NDRG1,FLOT1,CTNND1,TP53I11,SGCB,RHOB,SGPL1 |
| 2.332e-02 | -3.76 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | 30 | 9 | 17758 | 2588 |
MTM1,PI4K2B,INPPL1,PTEN,PIK3R1,INPP4B,PIK3CA,PIK3C2B,PIK3CD |
| 2.332e-02 | -3.76 | GNF2_EGFR | MSigDB lists | GNF2_EGFR | 30 | 9 | 17758 | 2588 |
TIMP2,CAPN6,ALPP,TFAP2A,GDF15,PLAC1,SDC1,MAFF,EGFR |
| 2.332e-02 | -3.76 | BIOCARTA_FAS_PATHWAY | MSigDB lists | BIOCARTA_FAS_PATHWAY | 30 | 9 | 17758 | 2588 |
CASP3,RB1,CASP7,RIPK2,PAK2,ARHGDIB,MAP3K7,LMNA,FAS |
| 2.335e-02 | -3.76 | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | MSigDB lists | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | 109 | 24 | 17758 | 2588 |
LASP1,BCAM,UGP2,PEX6,S100A11,CD63,MPP1,YES1,BCL2L1,ESYT1,ADAMTSL4,CMTM6,RAC2,GDE1,SH3BP1,FDXR,ARFGAP3,TAX1BP3,PIM1,MINPP1,CTSD,NAGA,CAPN1,SNPH |
| 2.335e-02 | -3.76 | PROTEIN_TARGETING | MSigDB lists | PROTEIN_TARGETING | 109 | 24 | 17758 | 2588 |
NAGPA,NFKBIE,AKT1,PEX6,PDIA3,STRADB,ICMT,BARD1,ZFYVE9,OPTN,ATG4A,CALR,ZFYVE16,AP1M2,CDH1,PPP1R10,KIF13B,BCL6,KPNA2,LTBP2,F2R,TRAM1,ATG4D,MDFI |
| 2.338e-02 | -3.76 | endosomal transport | biological process | GO:0016197 | 231 | 46 | 16441 | 2455 |
MTM1,SORT1,TRAPPC10,CD63,ARL4C,TGOLN2,RAB6A,MICALL2,SNX9,FAM21C,EMP2,RIC1,VPS26A,HMGXB4,M6PR,ZFYVE16,DOPEY2,SNX18,FAM160A2,ARL1,SNX16,TINAGL1,PIKFYVE,LMAN1,TBC1D10B,SNX8,VPS11,GCC2,VPS4B,VAMP3,AP5M1,KIF13A,ARFRP1,RAB38,FAM109A,RHOB,AP1AR,TBC1D17,STX10,HTT,WIPI1,CHMP4B,RAB29,HOOK1,ABCA1,EHD1 |
| 2.340e-02 | -3.75 | Dopaminergic synapse | KEGG pathways | hsa04728 | 129 | 29 | 6908 | 1076 |
AKT1,CALM1,GNAL,CALM3,ITPR2,ITPR3,PRKACA,FOS,GNB2,PPP2R3A,GNAS,KIF5B,CALM2,PPP2R5A,GNB5,ITPR1,PPP1CB,MAOA,PPP2R3C,MAPK11,MAPK13,CACNA1D,PPP1CA,PLCB2,PPP2R2D,PPP2R5D,CAMK2G,MAPK12,DRD1 |
| 2.340e-02 | -3.75 | Dopaminergic synapse | KEGG pathways | ko04728 | 129 | 29 | 6908 | 1076 |
AKT1,CALM1,GNAL,CALM3,ITPR2,ITPR3,PRKACA,FOS,GNB2,PPP2R3A,GNAS,KIF5B,CALM2,PPP2R5A,GNB5,ITPR1,PPP1CB,MAOA,PPP2R3C,MAPK11,MAPK13,CACNA1D,PPP1CA,PLCB2,PPP2R2D,PPP2R5D,CAMK2G,MAPK12,DRD1 |
| 2.342e-02 | -3.75 | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_UP | MSigDB lists | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_UP | 166 | 34 | 17758 | 2588 |
PRKAA2,EPAS1,FRMD6,CCDC68,RNF182,FAM101B,TMCC3,DAPK2,SS18,ITGB8,PAK2,PPP4R1,RUNDC3B,PIK3CA,ATP8B1,VAT1,DAB2IP,NTN4,SYTL3,IL1RAP,GPR161,TMEM43,SERTAD4,LITAF,FOS,CYP4F3,KDM4D,MAN2A2,IL1R1,CELF5,ZFP30,DGAT2,EFNA1,F2RL1 |
| 2.344e-02 | -3.75 | negative regulation of B cell apoptotic process | biological process | GO:0002903 | 12 | 5 | 16441 | 2455 |
IRS2,AURKB,SLC39A10,BCL6,BCL10 |
| 2.344e-02 | -3.75 | positive regulation of astrocyte differentiation | biological process | GO:0048711 | 12 | 5 | 16441 | 2455 |
BIN1,BMP2,HES1,SERPINE2,IL6ST |
| 2.344e-02 | -3.75 | fatty acid homeostasis | biological process | GO:0055089 | 12 | 5 | 16441 | 2455 |
PRKAA2,SIRT1,GOT1,PRKAA1,DGAT2 |
| 2.344e-02 | -3.75 | tooth mineralization | biological process | GO:0034505 | 12 | 5 | 16441 | 2455 |
CNNM4,FAM20C,STIM1,TBX1,PPARA |
| 2.344e-02 | -3.75 | iron ion import | biological process | GO:0097286 | 12 | 5 | 16441 | 2455 |
SLC11A2,STEAP3,MFI2,STEAP1,STEAP2 |
| 2.344e-02 | -3.75 | cellular response to ATP | biological process | GO:0071318 | 12 | 5 | 16441 | 2455 |
P2RX4,PTGS2,SOD1,HSP90B1,SSH1 |
| 2.344e-02 | -3.75 | regulation of glomerular filtration | biological process | GO:0003093 | 12 | 5 | 16441 | 2455 |
ADORA1,PDGFB,EMP2,F2R,F2RL1 |
| 2.344e-02 | -3.75 | glycerol ether metabolic process | biological process | GO:0006662 | 12 | 5 | 16441 | 2455 |
TXN,FAR2,FAR1,TMEM86B,AGPS |
| 2.344e-02 | -3.75 | regulation of peroxisome proliferator activated receptor signaling pathway | biological process | GO:0035358 | 12 | 5 | 16441 | 2455 |
SIRT1,TWIST1,CITED2,ASXL1,PLIN5 |
| 2.345e-02 | -3.75 | cellular response to unfolded protein | biological process | GO:0034620 | 112 | 25 | 16441 | 2455 |
GFPT1,SEC61B,HSP90B1,ADD1,SEC61G,AMFR,DNAJC3,ERO1A,PDIA5,KDELR3,DNAJB11,VCP,DNAJB9,LMNA,CCND1,CALR,WIPI1,WFS1,BAX,DAB2IP,YOD1,MYDGF,PDIA6,CTDSP2,CTH |
| 2.345e-02 | -3.75 | negative regulation of neuron projection development | biological process | GO:0010977 | 112 | 25 | 16441 | 2455 |
SEMA6B,RHOA,CIT,RAPGEF2,LRP4,EPHA4,ULK2,CDK5R1,DPYSL3,SPP1,PTEN,SEMA4D,PLK2,KIAA0319,RAB29,EFNA1,SEMA3G,ARF6,NTN1,WNT3A,GFI1,SEMA3A,ITM2C,NGEF,SEMA3B |
| 2.345e-02 | -3.75 | regulation of embryonic development | biological process | GO:0045995 | 112 | 25 | 16441 | 2455 |
HES1,TGIF1,LFNG,CCSAP,GATA3,OSR2,NPHP3,PRKACA,CDK1,DAG1,PPP2R3A,SIX4,FZD7,INSR,CTNNB1,BMP7,PTK7,TRAF3IP1,TBX18,NKD1,WNT3A,MAPK7,OSR1,DVL2,GPR161 |
| 2.352e-02 | -3.75 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | molecular function | GO:0016820 | 107 | 24 | 16491 | 2452 |
ATP8A1,ATP2C2,ABCG4,TAP1,ABCG2,ATP6V1E2,ATP1B1,ABCD4,ATP13A2,TAPBP,ATP6V0B,ATP1A1,ATP7B,ATP13A3,PCYOX1,ABCA2,ABCB1,ABCD1,ATP1B3,ATP6V1C1,ABCA1,ATP2B1,ABCG1,ABCC1 |
| 2.356e-02 | -3.75 | POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 55 | 14 | 17758 | 2588 |
CARD8,RALBP1,CASP9,PPP2R4,STAT1,ARAP1,TP53,BAX,F2R,AIFM3,PLCB2,EGFR,VCP,EDNRA |
| 2.356e-02 | -3.75 | WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | MSigDB lists | WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | 55 | 14 | 17758 | 2588 |
CCND1,TIMP3,ITGA3,ITGB8,LFNG,PLAUR,MICB,P4HA2,AXL,BMP1,S100A2,F2RL1,CRISPLD2,MAP1B |
| 2.356e-02 | -3.75 | PID_TGFBR_PATHWAY | MSigDB lists | PID_TGFBR_PATHWAY | 55 | 14 | 17758 | 2588 |
ZFYVE16,DYNLRB1,TGFBR3,RHOA,CTNNB1,CTGF,ITCH,XIAP,WWP1,TGFBR1,PPP1CA,MAP3K7,ZFYVE9,OCLN |
| 2.356e-02 | -3.75 | LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER | MSigDB lists | LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER | 207 | 41 | 17758 | 2588 |
TTC8,INPPL1,S100A11,ARHGEF11,SEC61G,DAP,TDRKH,BLCAP,GNB2,AIP,RAD23A,CORO1B,GNS,SIVA1,FJX1,PPP1R16A,PIK3CA,CKS1B,SRP54,APIP,PPP1CA,S100A13,S100A6,CERS2,SEC23A,AKT1,PSMB4,PAPD7,FIGNL1,IGSF8,NUBP1,CLCN2,EGFR,FAM177A1,NFKBIA,PPP2R3C,PLD1,ATP6V1C1,B4GALT3,ARNT,FOXA1 |
| 2.356e-02 | -3.75 | organophosphate ester transport | biological process | GO:0015748 | 85 | 20 | 16441 | 2455 |
SLC35D2,SLC25A24,ATP9A,ATP8A1,P2RX7,NPC2,ATP8B3,PCTP,CPTP,ATP10D,SLC25A36,TMEM30A,KCNN4,MFSD2A,SLC35B4,ATP8B1,PITPNA,SLC35A1,ABCA1,ABCG1 |
| 2.359e-02 | -3.75 | KEGG_ERBB_SIGNALING_PATHWAY | MSigDB lists | KEGG_ERBB_SIGNALING_PATHWAY | 87 | 20 | 17758 | 2588 |
AKT1,PIK3R1,ERBB2,NRG2,ELK1,CBL,EGFR,PAK6,PLCG1,AREG,SHC3,PAK2,PLCG2,PIK3CA,CDKN1B,NRG1,ERBB3,PIK3CD,GAB1,CAMK2G |
| 2.360e-02 | -3.75 | MODULE_46 | MSigDB lists | MODULE_46 | 388 | 71 | 17758 | 2588 |
IL15RA,IL15,DNAJC3,GATA3,ERBB2,IL18,IL27RA,MGST2,PDGFB,FLT3,EMP2,MXD1,PDGFA,IL6ST,CAPG,BCL6,TACSTD2,IFIT1,IL1RAP,LAMP3,MX1,CD55,PTGER4,CR2,ARHGDIB,CD40,ALCAM,EDNRA,MDK,FYN,AREG,P4HA2,STAT1,IRF7,GRN,HLA-F,EPS8,SELL,ETS1,IL18R1,HLA-A,LGALS3BP,GBX2,TIMP1,CTSC,CYR61,KCNN4,CD22,HLA-C,RAG1,IFITM3,EMP3,RUNX3,CDK5R1,CD83,FAS,IL1R1,HLA-B,CD8A,BTG1,SEMA4D,CSF1,NFKBIA,NAB2,OSMR,NR4A2,GEM,CD81,UBE2C,CSRP2,IRF1 |
| 2.363e-02 | -3.75 | CLIC4 (chloride intracellular channel 4) | protein interactions | 25932 | 46 | 13 | 16036 | 2547 |
TPRN,ST13,PSMB4,P4HB,HNRNPH2,NDRG1,SPRTN,CDA,EZR,TAGLN2,DAG1,PSMA5,SEPHS1 |
| 2.363e-02 | -3.75 | ITGAV (integrin alpha V) | protein interactions | 3685 | 46 | 13 | 16036 | 2547 |
CALR,SPP1,NOV,ITGB8,CYR61,FBXO6,CBL,ILK,PHKA2,BCAR1,F2R,L1CAM,LGALS3BP |
| 2.363e-02 | -3.75 | EEF2K (eukaryotic elongation factor 2 kinase) | protein interactions | 29904 | 46 | 13 | 16036 | 2547 |
MAPKAPK2,CALR,PRKAA2,MAPKAPK3,RPS6KA1,PRKAA1,DPP9,MAPK11,MAPK13,PRKACA,CDK1,MAPK12,METAP2 |
| 2.366e-02 | -3.74 | ACACTAC,MIR-142-3P | MSigDB lists | ACACTAC,MIR-142-3P | 126 | 27 | 17758 | 2588 |
MOB4,TMEM200B,SYPL1,SPRED1,MMD,TMEM55B,VAMP3,TGFBR1,LRRC1,MORF4L2,FNDC3A,TP53INP2,GNB2,PSIP1,IRAK1,LLGL2,MGAT4A,MAP3K11,SGK1,ITGAV,ACSL4,TFG,GFI1,TIPARP,CPEB2,RARG,C9orf72 |
| 2.368e-02 | -3.74 | digestive system development | biological process | GO:0055123 | 151 | 32 | 16441 | 2455 |
CDKN1C,LGR4,THRA,ITGA6,RET,GATA3,NCKAP1,CCNB1,TP73,PDGFA,RB1,CYP1A1,IGF1R,CTNNB1,GATA2,DACT1,MEGF8,SMO,EPB41L5,PDGFC,DCHS1,NPHP3,SAV1,FOXL1,EGFR,INSR,FAT4,FGFR2,KLF5,SHOX2,COBL,PCSK5 |
| 2.373e-02 | -3.74 | V$CHX10_01 | MSigDB lists | V$CHX10_01 | 213 | 42 | 17758 | 2588 |
PAX6,HOXB7,THRA,RHBDL3,IRX4,PRKACA,FGF19,LTBP3,GRM5,NEO1,CDKN2C,FOXP2,ADD3,RGS12,CA2,GRHL1,ELMO2,BHLHE41,FLRT3,GPC3,PPP1R16A,MITF,FOSB,BCL6,DIXDC1,WNT3A,BTBD3,CASK,PLEKHA6,SYNE2,CYFIP2,LDB2,NFIB,FZD7,SLC44A3,PITX2,FYN,RTN4RL1,BMP1,OVOL1,MAOA,SHOX2 |
| 2.380e-02 | -3.74 | GSE25087_TREG_VS_TCONV_ADULT_DN | MSigDB lists | GSE25087_TREG_VS_TCONV_ADULT_DN | 172 | 35 | 17758 | 2588 |
TRIM2,PDIA5,FLOT1,NDRG2,SLC20A1,C1orf116,IGF1R,AKR1B1,TNPO2,PIK3CD,BTBD3,CTDSP2,KCTD3,TPCN1,C9orf9,TMCC2,SYPL1,MRPS33,IFITM3,CBX6,C12orf65,ASB13,GIGYF1,PLEKHB1,NIN,CDK5RAP1,ANKRD10,SERTAD2,UTP14C,RIN3,TMOD2,TTC9,ZC3H12B,RPL22,TANC2 |
| 2.380e-02 | -3.74 | NOTCH_DN.V1_UP | MSigDB lists | NOTCH_DN.V1_UP | 172 | 35 | 17758 | 2588 |
RUNX2,CRYM,ATP8A1,HABP4,ASB9,RAB23,TGFBR1,PRKACA,FLT3,HPCAL4,SLC9A7,TTC21B,AIM1L,PAIP2B,KIF13B,KCNN4,PRKG1,ZNF230,RP2,IFIT1,NPTXR,LMAN1,RAG1,RASGRP1,FARP2,DLGAP1,SSH3,GRIN1,TNS1,DGKE,DHX32,EPN3,PIAS3,BHLHB9,CLMN |
| 2.380e-02 | -3.74 | BROWNE_HCMV_INFECTION_18HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_18HR_UP | 172 | 35 | 17758 | 2588 |
PRKAA2,PPP1R2,IL15,ATP8A1,SLC25A13,ETV5,TAP1,MRAS,PDIA4,CDS1,M6PR,ZFX,HSF2,MITF,RUNDC3B,KCNS3,WWP1,ZNF230,ERBB3,MPHOSPH9,RASGRP1,NEK4,ENPP4,ZWINT,KCTD2,DCP2,CD83,MAN2A2,GPRC5B,SLC25A4,NFKBIA,TRAF3IP1,PKIA,OCLN,FAM134B |
| 2.380e-02 | -3.74 | cysteine-type endopeptidase regulator activity involved in apoptotic process | molecular function | GO:0043028 | 44 | 12 | 16491 | 2452 |
CARD8,NKX3-1,PRDX3,CTSC,NGFRAP1,RPS6KA1,SERPINB9,XIAP,ARRB1,CDKN1B,BCL2L13,RPS6KA3 |
| 2.384e-02 | -3.74 | STAT1 (signal transducer and activator of transcription 1) | protein interactions | 6772 | 169 | 37 | 16036 | 2547 |
CASP3,ERBB2,IL27RA,GNB2,VPS26A,DTX3L,IRAK1,PAK2,TBCD,PIK3CA,IRF2,CTTN,SYK,CAMK2G,SMARCA2,SHMT1,AKT1,RNF11,FOS,POR,VCP,EGFR,MDK,HLA-B,FYN,CASP7,IDE,JAK1,NMI,NFKBIA,PPP2R4,STAT1,E2F1,HDAC1,KPNA2,ATP6V1C1,IRF1 |
| 2.389e-02 | -3.73 | CTTTGTA,MIR-524 | MSigDB lists | CTTTGTA,MIR-524 | 419 | 76 | 17758 | 2588 |
MTM1,PAX6,TMEM184B,ADD1,LGR4,HOXB7,IQGAP1,ATP8A1,CACNA2D2,C5orf30,MXD1,SIPA1L2,CPNE2,RNF220,WDR44,LMO4,LHX6,MITF,PTPRE,SP5,LAMP2,SSH3,PTPRU,ERBB2IP,GALNT7,PRKRA,TANC1,SESN1,SP4,NFIX,IRS2,PEX5,P4HA2,PPP1CB,HDAC1,ADIPOR1,RCAN2,ZBTB6,SPRY4,ABCA1,HOXC13,CTHRC1,SORT1,LRRFIP2,CPEB4,DCAF7,SOX9,PDCL,GPR180,NKRF,SLC1A3,GBX2,ZFX,ITGA3,LYPD3,KCNN4,ATP2B1,IGDCC4,HES1,PHF20L1,MOSPD2,STAT4,PRICKLE1,SRSF5,RANBP9,BSDC1,NCOA3,SLC6A6,ETS2,APPL2,NR4A3,NR4A2,SOX8,ZMIZ1,CBX5,CPEB2 |
| 2.389e-02 | -3.73 | juvenile_myelomonocytic_leukaemia | COSMIC cancer mutations | juvenile_myelomonocytic_leukaemia | 35 | 10 | 17775 | 2585 |
CALR,RB1,ASXL1,GATA2,ETNK1,CBL,IDH1,JAK3,FLT3,RAD21 |
| 2.389e-02 | -3.73 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-juvenile_myelomonocytic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-juvenile_myelomonocytic_leukaemia | 35 | 10 | 17775 | 2585 |
CALR,RB1,ASXL1,GATA2,ETNK1,CBL,IDH1,JAK3,FLT3,RAD21 |
| 2.390e-02 | -3.73 | DENN | pfam domains | PF02141 | 16 | 6 | 16629 | 2504 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 2.394e-02 | -3.73 | NERVOUS_SYSTEM_DEVELOPMENT | MSigDB lists | NERVOUS_SYSTEM_DEVELOPMENT | 376 | 69 | 17758 | 2588 |
DOC2A,UGT8,PAX6,NF2,AGRN,DNER,PICK1,ARTN,SHC3,DPYSL2,LMO4,LHX6,ARNT2,SEMA3B,SOD1,MBP,DPYSL3,ALDH5A1,RTN4RL1,PAFAH1B3,LIMK1,WFS1,EFNA5,SERPINI1,TMOD2,APBA2,NRGN,PPP2R5D,NR2C2,JRKL,CIT,PBX3,RACGAP1,NCKAP1,APBA1,GSTP1,FGF19,HPCAL4,NRP2,RND1,FOXP2,ADORA1,PTEN,CD9,TRIM3,NPTN,MYLIP,ALDH3A2,FARP2,POU6F1,DPYSL5,PDGFC,HES1,PCDH1,STMN3,DPYSL4,CDK5R1,BCL10,CTNS,TIMM8A,NAB2,GDF11,SOX8,DRP2,SHOX2,SHROOM2,L1CAM,RPS6KA3,JARID2 |
| 2.401e-02 | -3.73 | Valine, leucine and isoleucine degradation | KEGG pathways | hsa00280 | 47 | 13 | 6908 | 1076 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,MCCC1,AOX1,ALDH7A1,HMGCL,ACADM,ACAD8,ALDH3A2,MCCC2 |
| 2.401e-02 | -3.73 | Valine, leucine and isoleucine degradation | KEGG pathways | ko00280 | 47 | 13 | 6908 | 1076 |
PCCB,ALDH2,ACADSB,OXCT1,ALDH6A1,AOX1,MCCC1,ALDH7A1,HMGCL,ACADM,ACAD8,ALDH3A2,MCCC2 |
| 2.402e-02 | -3.73 | Platelet activation, signaling and aggregation | REACTOME pathways | R-HSA-76002 | 230 | 46 | 8202 | 1235 |
PLA2G4A,CD63,DGKQ,HABP4,DGKA,CALM3,ITPR2,PDGFB,GNB2,ITGA2B,CALM2,PDGFA,RAC2,GNB5,TIMP1,PLCG2,CD9,PIK3CA,PIK3CD,F2R,DGKG,SYK,RASGRP1,TUBA4A,LAMP2,SOD1,RHOA,AKT1,PIK3R1,CALM1,PRKCQ,ITPR3,BCAR1,GNA11,DGKE,RHOB,RASGRP2,DGKH,FYN,JAK1,SERPINA1,ABHD12,ITPR1,ARRB1,JAK3,TRPC3 |
| 2.409e-02 | -3.73 | spleen development | biological process | GO:0048536 | 39 | 11 | 16441 | 2455 |
PITX2,ONECUT1,ADAM17,RC3H2,PPP2R3C,PKN1,CITED2,NFKB2,CACNB4,JARID2,FAS |
| 2.409e-02 | -3.73 | negative chemotaxis | biological process | GO:0050919 | 39 | 11 | 16441 | 2455 |
PDGFA,SEMA6B,RHOA,SEMA4D,FLRT3,NRG1,EFNA5,ITGAV,SEMA3G,SEMA3A,SEMA3B |
| 2.409e-02 | -3.73 | negative regulation of transcription factor import into nucleus | biological process | GO:0042992 | 39 | 11 | 16441 | 2455 |
NOV,NFKBIE,THRA,BMP7,NFKBIA,LITAF,RAB23,PSMD10,PKD2,MAPK7,MDFI |
| 2.409e-02 | -3.73 | negative regulation of mitochondrion organization | biological process | GO:0010823 | 39 | 11 | 16441 | 2455 |
PPIF,PINK1,BAG4,AKT1,TP53,PSMD10,VAT1,BCL2L1,SLC25A5,LMNA,IER3 |
| 2.410e-02 | -3.73 | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | 370 | 68 | 17758 | 2588 |
GAA,PAX6,TSC22D3,GMPR,MGST2,SDC1,DDR1,SPTB,ARHGEF16,CDKL5,MITF,FOSB,LGMN,NFKB2,TIAM1,MX1,PRKAR2B,CD40,TCN2,MDK,HSF4,SERPINB6,HSPB1,GRN,PCOLCE,ENO2,HLA-F,CALB2,CRABP2,MERTK,EFNB1,HOXB2,ITGA2B,SIRPA,ITGA3,RPL39,CD22,CST3,DAPK1,CD9,SORL1,ALDH7A1,NCAM1,PLCB2,RBMS2,MYO5A,DUSP1,SYPL1,TGIF1,HES1,ALDH2,PCDH1,WNT10B,NR4A1,YES1,FOS,GNA11,GPLD1,CNTNAP1,MAPKAPK2,FUCA1,TIMP3,SERPINA1,CSF1,SPINT2,NFKBIA,HOXB13,LTBP2 |
| 2.411e-02 | -3.73 | third_ventricle | COSMIC cancer mutations | third_ventricle | 45 | 12 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,PTEN,RET,SMO,PIK3CA,TP53,IDH1,GNA11,EGFR |
| 2.412e-02 | -3.72 | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | MSigDB lists | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | 50 | 13 | 17758 | 2588 |
IL15,PLK2,TRAF2,AXL,RGS20,GATA3,DUSP10,GEM,ITPR3,AHR,ATP2B1,CYP1B1,TUBA4A |
| 2.412e-02 | -3.72 | REACTOME_APOPTOTIC_EXECUTION_PHASE | MSigDB lists | REACTOME_APOPTOTIC_EXECUTION_PHASE | 50 | 13 | 17758 | 2588 |
CASP3,CASP7,FNTA,ADD1,CTNNB1,CDH1,H1F0,DNM1L,PAK2,PRKCQ,BCAP31,OCLN,LMNA |
| 2.415e-02 | -3.72 | regulation of T cell proliferation | biological process | GO:0042129 | 140 | 30 | 16441 | 2455 |
HES1,CASP3,CD55,RIPK2,LGALS3,DHPS,IL15,ITCH,HLA-E,PDE5A,ERBB2,IL18,PRKCQ,CD274,TNFSF9,EFNB1,HLA-A,CD46,RAC2,CTNNB1,IL6ST,DLG1,IGFBP2,C10orf54,ICOSLG,NDFIP1,JAK3,SYK,PRKAR1A,IRF1 |
| 2.417e-02 | -3.72 | insulin-like growth factor binding | molecular function | GO:0005520 | 25 | 8 | 16491 | 2452 |
NOV,INSR,IGF1R,CTGF,IGFBP6,CYR61,IGFBP2,ITGAV |
| 2.419e-02 | -3.72 | regulation of homotypic cell-cell adhesion | biological process | GO:0034110 | 296 | 57 | 16441 | 2455 |
CASP3,SERPINE2,LGALS3,DHPS,IL15,HLA-E,UBASH3B,TRAF2,GATA3,ERBB2,IL18,EGR3,CD274,TNFSF9,EFNB1,HLA-A,CD46,RAC2,CTNNB1,IL6ST,PAK2,BCL6,PIK3CA,DLG1,PRKG1,IGFBP2,C10orf54,MAP3K7,RAG1,FLOT2,SYK,RASGRP1,SOCS5,HES1,SOD1,CD55,RHOA,RIPK2,AKT1,LGALS8,ITCH,DMTN,PIK3R1,PDE5A,PRKCQ,YES1,SOX13,BCL10,CD83,FYN,NOD2,NR4A3,ICOSLG,NDFIP1,JAK3,PRKAR1A,IRF1 |
| 2.420e-02 | -3.72 | PECAM1 interactions | REACTOME pathways | R-HSA-210990 | 12 | 5 | 8202 | 1235 |
PLCG1,FYN,YES1,ITGAV,INPP5D |
| 2.420e-02 | -3.72 | Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | REACTOME pathways | R-HSA-1474151 | 12 | 5 | 8202 | 1235 |
CALM2,CALM3,AKT1,SPR,CALM1 |
| 2.420e-02 | -3.72 | Defective EXT2 causes exostoses 2 | REACTOME pathways | R-HSA-3656237 | 12 | 5 | 8202 | 1235 |
HSPG2,AGRN,SDC1,GPC3,SDC4 |
| 2.420e-02 | -3.72 | Defective EXT1 causes exostoses 1, TRPS2 and CHDS | REACTOME pathways | R-HSA-3656253 | 12 | 5 | 8202 | 1235 |
HSPG2,AGRN,SDC1,GPC3,SDC4 |
| 2.422e-02 | -3.72 | GNF2_RAP1B | MSigDB lists | GNF2_RAP1B | 35 | 10 | 17758 | 2588 |
RAC2,JAK1,HLA-E,STK38,INPP5D,IQGAP1,HLA-F,CAB39,OSTF1,FAM134C |
| 2.422e-02 | -3.72 | WEIGEL_OXIDATIVE_STRESS_BY_TBH_AND_H2O2 | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_BY_TBH_AND_H2O2 | 35 | 10 | 17758 | 2588 |
CAPN2,QSOX1,RB1,ZYX,SPINT2,TP53,HDAC1,HSPA13,HLA-C,CDC25C |
| 2.423e-02 | -3.72 | BURTON_ADIPOGENESIS_2 | MSigDB lists | BURTON_ADIPOGENESIS_2 | 71 | 17 | 17758 | 2588 |
AVPI1,NF2,SDC1,SPSB1,MAP3K6,PER2,IL1R1,TGFBR3,SLC6A6,TIMP1,LIMK1,GNPTAB,KCNN4,TLE1,ST3GAL1,PTGES,XDH |
| 2.423e-02 | -3.72 | KEGG_GLYCEROPHOSPHOLIPID_METABOLISM | MSigDB lists | KEGG_GLYCEROPHOSPHOLIPID_METABOLISM | 71 | 17 | 17758 | 2588 |
PLA2G4A,CDS2,LPGAT1,DGKQ,DGKA,ETNK1,PHOSPHO1,PLD2,CDIPT,DGKE,CDS1,DGKH,AGPAT2,PLA2G15,PLD1,DGKG,CHPT1 |
| 2.425e-02 | -3.72 | GTTTGTT,MIR-495 | MSigDB lists | GTTTGTT,MIR-495 | 243 | 47 | 17758 | 2588 |
TRAPPC10,TSC22D3,SOX9,WDTC1,UBE2Z,UBE2Q1,NKRF,JAG2,MORF4L2,PRR7,ETS1,NFAT5,SSX2IP,HMGXB4,APPBP2,PER2,ZFX,PDCD10,MDM1,BHLHE41,RANBP1,ABCA2,SGK1,PDE4D,EPB41L4B,CAMK2G,DCAF6,TIMP2,MLEC,NRBF2,CDYL,RUNX3,SRSF5,CBL,ZFAND5,DAG1,SP4,PLCH1,RND3,HNRNPH2,MYLK,NAB2,AGBL5,KLF5,LRRK1,GLCCI1,CBX4 |
| 2.429e-02 | -3.72 | limbic system development | biological process | GO:0021761 | 96 | 22 | 16441 | 2455 |
ANXA3,CASP3,NF2,CNTNAP2,BBS2,ETS1,CDK5R1,TP73,MDK,TSC1,PTEN,FGFR2,PHLPP2,KIF14,ALDH1A3,BAX,SMO,NR4A3,WNT3A,ZBTB18,SEMA3A,DRD1 |
| 2.430e-02 | -3.72 | V$TCF1P_Q6 | MSigDB lists | V$TCF1P_Q6 | 249 | 48 | 17758 | 2588 |
KIF3C,BCAM,PAX6,CPEB4,HOXB7,GGA1,UBE2Z,COL18A1,BLCAP,ART5,NEO1,CDKN2C,SCNN1A,LMO4,BHLHE41,KLF3,DLG1,FXYD5,DUSP10,PIK3CD,SCN2A,RBMS2,SEPHS1,PLK1,TGIF1,MCTP1,TEF,UXT,SAT1,PIK3R1,CDYL,RGAG1,PLS1,PTGFRN,FOS,SP4,PITX2,ZNF367,SLC9A6,AMMECR1,NAB2,FAM117A,EFNA5,ARF6,SEMA3A,PPP2R5D,JARID2,HS6ST3 |
| 2.430e-02 | -3.72 | V$MYB_Q5_01 | MSigDB lists | V$MYB_Q5_01 | 249 | 48 | 17758 | 2588 |
LTBP1,PPP4R4,FAF2,HEBP1,CDCA3,FAM91A1,PRKACA,SIX4,PRRG4,SLC9A7,CDK14,FOXP2,MDM1,SLC16A6,DACT1,TMEM62,FRAS1,OCRL,LHX6,TOX2,FAM63A,MXD3,STT3B,MANF,ETV4,TMED2,ZNF462,PGM1,SMARCA2,SHMT1,SLC37A1,KIF20A,COQ10B,OGDHL,PRICKLE1,C12orf65,SRSF5,GNAS,CRTC2,ONECUT1,MPRIP,KLF12,WIPI1,KLF5,NRG1,NRGN,NR3C2,RARG |
| 2.431e-02 | -3.72 | KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION | MSigDB lists | KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION | 115 | 25 | 17758 | 2588 |
MYL9,CD99,RHOA,PIK3R1,EZR,F11R,BCAR1,MYL12A,ICAM1,TXK,ARHGAP35,PLCG1,RAC2,VASP,CTNNB1,PLCG2,PIK3CA,CLDN4,CTNND1,MAPK13,MAPK11,PIK3CD,MYL12B,OCLN,MAPK12 |
| 2.431e-02 | -3.72 | CHEBOTAEV_GR_TARGETS_DN | MSigDB lists | CHEBOTAEV_GR_TARGETS_DN | 115 | 25 | 17758 | 2588 |
PLA2G4A,CHSY3,MYL9,ATP8A1,S100A4,USP18,LRP4,PTGER4,VWA1,CACNB4,CA8,RSAD1,SH3KBP1,CRISPLD2,PDLIM3,FAM20C,ANKRD6,ZNF704,LIMCH1,SLC39A10,LOXL1,CPE,PKIA,IGDCC4,DMPK |
| 2.432e-02 | -3.72 | Inactivation, recovery and regulation of the phototransduction cascade | REACTOME pathways | R-HSA-2514859 | 34 | 10 | 8202 | 1235 |
CALM2,RGS9,FNTA,GNB5,CALM1,CALM3,PRKCQ,CNGA1,NMT2,METAP2 |
| 2.439e-02 | -3.71 | carbohydrate derivative catabolic process | biological process | GO:1901136 | 174 | 36 | 16441 | 2455 |
AGRN,HSPG2,GNPDA1,HEXB,SDC4,FBXO2,APOBEC3H,FBXO6,SDC1,GNS,TYMP,ENTPD4,MGAT1,GPC3,GALNS,AHCY,PDE4D,STT3B,NAGA,APOBEC3G,GM2A,CHP1,ENPP4,HMMR,GUSB,CDA,PDE5A,PDE11A,FUCA1,NUDT16,NEIL1,HPSE,ABHD12,GLB1,GLA,ARSB |
| 2.442e-02 | -3.71 | endometrium-hyperplasia-complex-atypical | COSMIC cancer mutations | endometrium-hyperplasia-complex-atypical | 5 | 3 | 17775 | 2585 |
CTNNB1,PTEN,PIK3CA |
| 2.442e-02 | -3.71 | pneumocytoma_(sclerosing_haemangioma) | COSMIC cancer mutations | pneumocytoma_(sclerosing_haemangioma) | 5 | 3 | 17775 | 2585 |
ERBB2,EGFR,TP53 |
| 2.442e-02 | -3.71 | central_nervous_system-cerebral_cortex-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-cerebral_cortex-glioma-oligodendroglioma_Grade_III | 5 | 3 | 17775 | 2585 |
IDH1,PTEN,TP53 |
| 2.442e-02 | -3.71 | lung-carcinoma-lymphoepithelioma_like_carcinoma | COSMIC cancer mutations | lung-carcinoma-lymphoepithelioma_like_carcinoma | 5 | 3 | 17775 | 2585 |
KIF5B,EGFR,TP53 |
| 2.442e-02 | -3.71 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-primary_effusion_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-primary_effusion_lymphoma | 5 | 3 | 17775 | 2585 |
CTNNB1,PTEN,PIK3CA |
| 2.442e-02 | -3.71 | large_intestine-rectum-other-hamartoma | COSMIC cancer mutations | large_intestine-rectum-other-hamartoma | 5 | 3 | 17775 | 2585 |
GNAS,CTNNB1,TP53 |
| 2.442e-02 | -3.71 | central_nervous_system-frontotemporal-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-frontotemporal-primitive_neuroectodermal_tumour-medulloblastoma | 5 | 3 | 17775 | 2585 |
CTNNB1,IDH1,TP53 |
| 2.442e-02 | -3.71 | lung-right_upper_lobe-carcinoma-acinar_adenocarcinoma | COSMIC cancer mutations | lung-right_upper_lobe-carcinoma-acinar_adenocarcinoma | 5 | 3 | 17775 | 2585 |
ERBB2,EGFR,TP53 |
| 2.442e-02 | -3.71 | bone-humerus-osteosarcoma-osteoblastic | COSMIC cancer mutations | bone-humerus-osteosarcoma-osteoblastic | 5 | 3 | 17775 | 2585 |
ERBB2,RB1,IDH1 |
| 2.442e-02 | -3.71 | lung-other-pneumocytoma_(sclerosing_haemangioma) | COSMIC cancer mutations | lung-other-pneumocytoma_(sclerosing_haemangioma) | 5 | 3 | 17775 | 2585 |
ERBB2,EGFR,TP53 |
| 2.442e-02 | -3.71 | kidney-Wilms_tumour-bilateral | COSMIC cancer mutations | kidney-Wilms_tumour-bilateral | 5 | 3 | 17775 | 2585 |
CTNNB1,AMER1,TP53 |
| 2.442e-02 | -3.71 | breast-carcinoma-medullary_carcinoma | COSMIC cancer mutations | breast-carcinoma-medullary_carcinoma | 5 | 3 | 17775 | 2585 |
AKT1,PIK3CA,TP53 |
| 2.442e-02 | -3.71 | central_nervous_system-frontal_lobe-glioma-ependymoma_Grade_III-IV | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-ependymoma_Grade_III-IV | 5 | 3 | 17775 | 2585 |
NF2,IDH1,TP53 |
| 2.442e-02 | -3.71 | frontobasal | COSMIC cancer mutations | frontobasal | 5 | 3 | 17775 | 2585 |
CTNNB1,IDH1,TP53 |
| 2.442e-02 | -3.71 | primary_effusion_lymphoma | COSMIC cancer mutations | primary_effusion_lymphoma | 5 | 3 | 17775 | 2585 |
CTNNB1,PTEN,PIK3CA |
| 2.442e-02 | -3.71 | complex-atypical | COSMIC cancer mutations | complex-atypical | 5 | 3 | 17775 | 2585 |
CTNNB1,PTEN,PIK3CA |
| 2.442e-02 | -3.71 | bone-tibia-osteosarcoma-chondroblastic | COSMIC cancer mutations | bone-tibia-osteosarcoma-chondroblastic | 5 | 3 | 17775 | 2585 |
ERBB2,RB1,IDH1 |
| 2.442e-02 | -3.71 | sebaceous_carcinoma | COSMIC cancer mutations | sebaceous_carcinoma | 5 | 3 | 17775 | 2585 |
CTNNB1,EGFR,MSH2 |
| 2.442e-02 | -3.71 | bilateral | COSMIC cancer mutations | bilateral | 5 | 3 | 17775 | 2585 |
CTNNB1,AMER1,TP53 |
| 2.442e-02 | -3.71 | astroblastoma_Grade_III | COSMIC cancer mutations | astroblastoma_Grade_III | 5 | 3 | 17775 | 2585 |
IDH1,PTEN,TP53 |
| 2.442e-02 | -3.71 | central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_III | 5 | 3 | 17775 | 2585 |
IDH1,MSH6,MSH2 |
| 2.444e-02 | -3.71 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP | 184 | 37 | 17758 | 2588 |
BIN1,ARHGEF3,UGT8,CHCHD7,CAST,FXYD3,SELL,CYB561,FAM198B,SRPX2,EXT2,LGALS3BP,TMEM63A,EPCAM,ADD3,HSF2,TRANK1,IL6ST,WWP1,ALPK1,ECE1,S100A13,DUSP1,MBP,TMEM43,STAT4,MTRF1L,SRSF5,SESN1,EGFR,USP6,TXK,HLA-B,BTG1,KBTBD2,ZDHHC7,IRF7 |
| 2.444e-02 | -3.71 | GSE27786_NKCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_NKCELL_VS_ERYTHROBLAST_UP | 184 | 37 | 17758 | 2588 |
UNC93B1,TTC39B,PPM1J,ASL,HMGN3,FBXO6,EXT2,AIM1,ZDHHC13,IRF2,RPN2,C10orf54,LRIF1,FAR1,FLOT2,TMEM68,PLSCR1,KIAA1841,ACO1,ASB13,ICMT,STX3,ZMPSTE24,CNOT2,AXL,CDCA7L,NAB2,SPAG7,TRIM45,GLB1,PLXND1,LSM14B,ARF6,TMEM120A,NRBP1,CPEB2,ZBTB33 |
| 2.448e-02 | -3.71 | REGULATION_OF_CELL_GROWTH | MSigDB lists | REGULATION_OF_CELL_GROWTH | 45 | 12 | 17758 | 2588 |
CDKN2C,CDKN2AIP,RB1,SERTAD2,SERTAD3,BCL6,TP53,CDA,CDKN1B,CDKN2D,BCAR1,OSGIN1 |
| 2.448e-02 | -3.71 | WARTERS_IR_RESPONSE_5GY | MSigDB lists | WARTERS_IR_RESPONSE_5GY | 45 | 12 | 17758 | 2588 |
DDB2,E2F7,PCNA,NGFRAP1,PHLDB3,FDXR,GDF15,FAM198B,FAM84B,SESN1,FAS,WDR63 |
| 2.448e-02 | -3.71 | NAKAJIMA_MAST_CELL | MSigDB lists | NAKAJIMA_MAST_CELL | 45 | 12 | 17758 | 2588 |
ENO2,LGALS3,TIMP1,GATA2,CALB2,CAPG,VAT1,GDF15,GLA,TRIB2,CTSD,CYP1B1 |
| 2.448e-02 | -3.71 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | MSigDB lists | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | 45 | 12 | 17758 | 2588 |
CCNE2,IL1R1,KLK10,PAX6,TIMP3,CDKN1C,ST14,CSF1,CDH3,TP53I11,BARD1,IFI6 |
| 2.450e-02 | -3.71 | regulation of G-protein coupled receptor protein signaling pathway | biological process | GO:0008277 | 129 | 28 | 16441 | 2455 |
KLK5,CALM1,PDCL,RGS20,CALM3,SYP,KLK6,PLD2,PRKCQ,GRK6,GRM5,NMT2,CALM2,RGS9,RGS12,FNTA,ADRBK1,GNB5,RGS3,DNM2,ARRB1,RGS5,TMOD2,PDE4D,GPER1,CNGA1,RGS14,METAP2 |
| 2.452e-02 | -3.71 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | REACTOME pathways | R-HSA-174178 | 69 | 17 | 8202 | 1235 |
PLK1,PSMB4,PSME2,PTTG1,CDC20,PSMD7,PSMD10,PSME1,AURKB,PSMA4,PSMD1,PSMD3,PSMC2,AURKA,UBE2C,PSMC1,PSMA5 |
| 2.453e-02 | -3.71 | regulation of chondrocyte differentiation | biological process | GO:0032330 | 44 | 12 | 16441 | 2455 |
RUNX2,CTNNB1,CTGF,ACVRL1,SOX9,FGF18,TGFBR1,LOXL2,SHOX2,FAM101B,RARG,POR |
| 2.453e-02 | -3.71 | regulation of cellular carbohydrate catabolic process | biological process | GO:0043471 | 44 | 12 | 16441 | 2455 |
PRKAA2,INSR,PRKAG2,PRKAA1,PPARA,TP53,P2RX7,PPP1CB,PPP1CA,ARNT,PHKG2,IER3 |
| 2.453e-02 | -3.71 | negative regulation of lipid biosynthetic process | biological process | GO:0051055 | 44 | 12 | 16441 | 2455 |
BMP2,PDGFA,SIRT1,SOD1,ATP1A1,PRKAA1,WDTC1,SLC27A1,GPER1,PDGFB,GFI1,FGF19 |
| 2.453e-02 | -3.71 | regulation of carbohydrate catabolic process | biological process | GO:0043470 | 44 | 12 | 16441 | 2455 |
PRKAA2,INSR,PRKAG2,PRKAA1,PPARA,TP53,P2RX7,PPP1CB,PPP1CA,ARNT,PHKG2,IER3 |
| 2.453e-02 | -3.71 | thymus development | biological process | GO:0048538 | 44 | 12 | 16441 | 2455 |
HES1,SOD1,CTNNB1,TBX1,LMO4,GATA3,TGFBR1,RAG1,CCNB2,CACNB4,SIX4,JARID2 |
| 2.454e-02 | -3.71 | skin-back-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-Spitz | 21 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.454e-02 | -3.71 | skin-buttock-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-buttock-benign_melanocytic_nevus-Spitz | 21 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.454e-02 | -3.71 | skin-chest-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-chest-benign_melanocytic_nevus-Spitz | 21 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.454e-02 | -3.71 | skin-upper_leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-upper_leg-benign_melanocytic_nevus-Spitz | 21 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.454e-02 | -3.71 | skin-leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-leg-benign_melanocytic_nevus-Spitz | 21 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.454e-02 | -3.71 | skin-foot-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-foot-benign_melanocytic_nevus-Spitz | 21 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.454e-02 | -3.71 | skin-shoulder-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-shoulder-benign_melanocytic_nevus-Spitz | 21 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 2.454e-02 | -3.71 | salivary_gland-carcinoma-mucoepidermoid_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-mucoepidermoid_carcinoma | 21 | 7 | 17775 | 2585 |
ERBB2,CTNNB1,CHCHD7,PTEN,EGFR,PIK3CA,TP53 |
| 2.455e-02 | -3.71 | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | MSigDB lists | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | 40 | 11 | 17758 | 2588 |
PLA2G4A,CD55,EPAS1,KCNK1,PLAUR,SDC4,SOD2,MEST,HSPA2,IL18R1,IER3 |
| 2.455e-02 | -3.71 | chr10q21 | MSigDB lists | chr10q21 | 40 | 11 | 17758 | 2588 |
SIRT1,ZWINT,CCDC6,ADO,ADAMTS14,EIF4EBP2,RTKN2,ZNF365,CDK1,VPS26A,SGPL1 |
| 2.455e-02 | -3.71 | ACTIVATION_OF_MAPK_ACTIVITY | MSigDB lists | ACTIVATION_OF_MAPK_ACTIVITY | 40 | 11 | 17758 | 2588 |
SOD1,MADD,KIAA1804,MAP3K11,MAP3K9,MDFIC,PKN1,MAP3K5,CD81,MAP3K6,MDFI |
| 2.455e-02 | -3.71 | NEGATIVE_REGULATION_OF_GROWTH | MSigDB lists | NEGATIVE_REGULATION_OF_GROWTH | 40 | 11 | 17758 | 2588 |
CDKN2C,CDKN2AIP,RB1,SERTAD2,SERTAD3,BCL6,TP53,CDA,CDKN1B,CDKN2D,OSGIN1 |
| 2.455e-02 | -3.71 | FUJII_YBX1_TARGETS_UP | MSigDB lists | FUJII_YBX1_TARGETS_UP | 40 | 11 | 17758 | 2588 |
CAPG,NLRC5,POF1B,DIAPH2,PRICKLE1,ACTA2,KLF11,TRIB2,SEPP1,S100A6,FAS |
| 2.456e-02 | -3.71 | KAPOSI_LIVER_CANCER_MET_DN | MSigDB lists | KAPOSI_LIVER_CANCER_MET_DN | 5 | 3 | 17758 | 2588 |
ALDH6A1,PIK3R1,EPHX1 |
| 2.456e-02 | -3.71 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | MSigDB lists | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | 5 | 3 | 17758 | 2588 |
HMGA1,APOBEC3G,PSIP1 |
| 2.456e-02 | -3.71 | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_UP | 5 | 3 | 17758 | 2588 |
CALR,LDB2,FBLN1 |
| 2.456e-02 | -3.71 | ELVIDGE_HIF2A_TARGETS_UP | MSigDB lists | ELVIDGE_HIF2A_TARGETS_UP | 5 | 3 | 17758 | 2588 |
SORL1,OSTM1,RET |
| 2.456e-02 | -3.71 | TOMIDA_LUNG_CANCER_POOR_SURVIVAL | MSigDB lists | TOMIDA_LUNG_CANCER_POOR_SURVIVAL | 5 | 3 | 17758 | 2588 |
DNER,DLX4,CKAP4 |
| 2.456e-02 | -3.71 | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX3 | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX3 | 5 | 3 | 17758 | 2588 |
IGF1R,SOX9,PDIA4 |
| 2.456e-02 | -3.71 | CAFFAREL_RESPONSE_TO_THC_8HR_3_UP | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_8HR_3_UP | 5 | 3 | 17758 | 2588 |
EPCAM,CPEB4,RHOB |
| 2.456e-02 | -3.71 | LAU_APOPTOSIS_CDKN2A_DN | MSigDB lists | LAU_APOPTOSIS_CDKN2A_DN | 5 | 3 | 17758 | 2588 |
TIMP3,FAIM,AKT1 |
| 2.457e-02 | -3.71 | Angiogenesis | WikiPathways | WP1539 | 23 | 8 | 4455 | 729 |
PLCG1,TIMP3,TIMP2,AKT1,FGFR2,PIK3CA,PDGFB,ARNT |
| 2.458e-02 | -3.71 | regulation of protein stability | biological process | GO:0031647 | 197 | 40 | 16441 | 2455 |
LAMP1,PINK1,TRIM24,NF2,PEX6,ISOC2,NCKAP1,HDAC6,BMP2,CALR,NAPG,PDCD10,RNF128,PTEN,DACT1,FBXO7,SMO,TRIM21,TSPAN1,MYLIP,FLOT2,CRTAP,CHP1,PLK1,SIRT1,LAMP2,VPS11,CDKN2AIP,WNT10B,PIK3R1,ATP1B1,SAV1,TSC1,WFS1,PLPP3,PEX2,AURKA,CTSA,ATP1B3,CD81 |
| 2.463e-02 | -3.70 | TLE1 (transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)) | protein interactions | 7088 | 106 | 25 | 16036 | 2547 |
SIRT1,HES1,PLSCR4,RUNX2,CUL4B,SERPINB9,SAT1,AES,RUNX3,BCL2L1,MORF4L2,CDK1,SIX4,SMN1,CDKN2C,SS18,CTNNB1,PAFAH1B3,IL6ST,PEX2,NOD2,HDAC1,TLE1,ARL4D,FOXA1 |
| 2.463e-02 | -3.70 | NCOA1 (nuclear receptor coactivator 1) | protein interactions | 8648 | 106 | 25 | 16036 | 2547 |
THRB,TRIM24,NR3C1,NR4A1,THRA,ITCH,PPARA,TP53,FOS,ETS1,SYTL2,VCP,CCND1,NCOA3,ETS2,STAT6,TRIM21,KANK2,HSPA2,NR3C2,AHR,ARNT,RARG,KCTD3,NCOA2 |
| 2.468e-02 | -3.70 | cytokine production | biological process | GO:0001816 | 118 | 26 | 16441 | 2455 |
CD55,ADGRG1,RGCC,BTN3A1,BTN3A2,GATA3,IL18,RNF19B,LTBP3,NFAT5,OPTN,TXK,BCL10,CD46,PTGS2,DLG1,NOD2,IRF7,PIK3CD,F2RL1,S100A13,ABCA1,IL1RAP,RASGRP1,TMEM173,PCSK5 |
| 2.469e-02 | -3.70 | CTNND1 (catenin (cadherin-associated protein), delta 1) | protein interactions | 1500 | 51 | 14 | 16036 | 2547 |
FYN,PTPRJ,CTNNB1,CDH1,GRIK2,CDH3,AURKA,CTNND1,CTTN,YES1,ERBB2IP,ZBTB33,VCP,EGFR |
| 2.469e-02 | -3.70 | ABI1 (abl-interactor 1) | protein interactions | 10006 | 51 | 14 | 16036 | 2547 |
VASP,PAK2,PRKAA1,EPS8,PIK3R1,RYK,DNM2,CTTN,NCKAP1,CBL,CYFIP2,NEB,EPS8L2,NIN |
| 2.471e-02 | -3.70 | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_UP | 190 | 38 | 17758 | 2588 |
EXPH5,FARP1,CUL4B,OAT,CCNB1,PSIP1,ARHGEF16,ZNF212,CTNNBIP1,CTNNB1,STIM1,ATP5H,NECAB3,FABP6,MSH2,FUT1,RPN2,USP1,KNTC1,CNPY3,FAM134C,PPIF,MOB4,PRODH,PTPN18,RHOA,COG2,PTPN9,SEPT6,GRIN1,PYGL,YES1,PRDX3,PRCP,SLC9A6,PGRMC1,ABCB1,RUSC1 |
| 2.471e-02 | -3.70 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_DN | 190 | 38 | 17758 | 2588 |
CCDC109B,NFKBIE,CKAP2,ATP8A1,ITGA6,DGKA,CNTNAP2,NCKAP1,SH3KBP1,EPCAM,PHTF1,SMO,TNFRSF18,RAG1,ITM2C,SYTL3,SUN2,RHOA,MRPS33,PQLC3,NR3C1,SEPT6,PRKCQ,TNFAIP8L1,ERP44,ATP1B1,BLVRA,CBL,DGKE,PTPRF,TMEM50B,SLC35B3,AXL,HMGA1,PLIN3,RGS14,AHR,TMEM131 |
| 2.471e-02 | -3.70 | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | MSigDB lists | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | 190 | 38 | 17758 | 2588 |
CD99,PAX6,HOXB7,GNPDA1,ITGA6,PTTG1,CNTROB,TSEN34,CYHR1,WEE1,DAZAP1,SH3BP1,METTL7A,LMO4,AIM1,PCYOX1,MTMR10,ABCD1,PHKA2,RCAN3,RNF26,S100A6,PAQR7,PTPN18,PLEKHO1,NUSAP1,TNFAIP8L1,ESYT1,SESN1,MYOM1,NFIX,NCOA3,COQ10A,H1F0,DOLPP1,ARRB1,MELK,IRF1 |
| 2.471e-02 | -3.70 | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDM_DN | 190 | 38 | 17758 | 2588 |
WASF3,BCAM,FRMD6,RUSC2,RHBDL3,PSMD7,EGR3,NOTCH2,PLA2G16,ZNF212,PLS3,IER3,SRP54,KANK2,APIP,CTTN,PTPRE,IL10RB,TSPAN33,FAH,CPD,SYPL1,PLSCR1,ACBD3,CD40,IRS2,MAPKAPK2,RGS9,PTPRJ,ATP1A1,ETS2,TMEM54,ZFP30,PPP1CB,ICOSLG,MAFF,CSRP2,JARID2 |
| 2.471e-02 | -3.70 | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDM_UP | 190 | 38 | 17758 | 2588 |
GRN,CCNI,FAM160B1,CHCHD7,GNPDA1,RALBP1,HEBP1,IQGAP1,TGFBR1,LTBP3,CDK16,CD22,IL6ST,TFAP2A,ADAM15,TAX1BP3,MAPK11,BUB1,GCNT1,P2RX4,MBP,ZC3H11A,CDC20,ACO1,ERBB2IP,CYP4F3,FRMD4B,SLC44A3,ANKRD10,PIAS3,CARHSP1,ENPP1,LDLRAP1,INSR,PNPLA6,ARRB1,CTSA,JARID2 |
| 2.472e-02 | -3.70 | ABC_2_trans | interpro domains | IPR013525 | 5 | 3 | 18293 | 2672 |
ABCG1,ABCG4,ABCG2 |
| 2.472e-02 | -3.70 | TF_AP2 | interpro domains | IPR004979 | 5 | 3 | 18293 | 2672 |
TFAP2C,TFAP2A,TFAP2E |
| 2.472e-02 | -3.70 | BRO1_dom | interpro domains | IPR004328 | 5 | 3 | 18293 | 2672 |
RHPN2,BROX,RHPN1 |
| 2.472e-02 | -3.70 | FAD-bd_2_sub1 | interpro domains | IPR016167 | 5 | 3 | 18293 | 2672 |
AGPS,AOX1,XDH |
| 2.472e-02 | -3.70 | Syntrophin | interpro domains | IPR015482 | 5 | 3 | 18293 | 2672 |
SNTA1,SNTB1,SNTB2 |
| 2.472e-02 | -3.70 | Lysosome-assoc_membr_glycop | interpro domains | IPR002000 | 5 | 3 | 18293 | 2672 |
LAMP2,LAMP1,LAMP3 |
| 2.472e-02 | -3.70 | TF_AP2_C | interpro domains | IPR013854 | 5 | 3 | 18293 | 2672 |
TFAP2C,TFAP2A,TFAP2E |
| 2.472e-02 | -3.70 | CD81_LEL | interpro domains | IPR028977 | 5 | 3 | 18293 | 2672 |
CD81,TSPAN6,CD9 |
| 2.472e-02 | -3.70 | Choline_transptr-like | interpro domains | IPR007603 | 5 | 3 | 18293 | 2672 |
SLC44A2,SLC44A1,SLC44A3 |
| 2.472e-02 | -3.70 | Dullard_phosphatase | interpro domains | IPR011948 | 5 | 3 | 18293 | 2672 |
CTDSP2,CTDSPL,CTDSP1 |
| 2.472e-02 | -3.70 | PQ-loop_rpt | interpro domains | IPR006603 | 5 | 3 | 18293 | 2672 |
PQLC2,CTNS,PQLC3 |
| 2.472e-02 | -3.70 | IGFBP_CNN | interpro domains | IPR012395 | 5 | 3 | 18293 | 2672 |
NOV,CTGF,CYR61 |
| 2.472e-02 | -3.70 | UbiB_dom | interpro domains | IPR004147 | 5 | 3 | 18293 | 2672 |
ADCK5,ADCK3,ADCK2 |
| 2.475e-02 | -3.70 | glycogen biosynthetic process | biological process | GO:0005978 | 25 | 8 | 16441 | 2455 |
PGM1,UGP2,AKT1,PGM2L1,GYS1,PHKG2,EPM2A,PER2 |
| 2.475e-02 | -3.70 | negative regulation of embryonic development | biological process | GO:0045992 | 25 | 8 | 16441 | 2455 |
CTNNB1,LFNG,BMP7,TRAF3IP1,GATA3,PRKACA,GPR161,FZD7 |
| 2.475e-02 | -3.70 | positive regulation of DNA-templated transcription, initiation | biological process | GO:2000144 | 25 | 8 | 16441 | 2455 |
CTNNB1,WNT10B,PSMC2,MITF,GTF2F2,TWIST1,AHR,PSMC1 |
| 2.475e-02 | -3.70 | regulation of cellular senescence | biological process | GO:2000772 | 25 | 8 | 16441 | 2455 |
NEK4,SIRT1,NUAK1,BCL6,TP53,TWIST1,HMGA1,VASH1 |
| 2.475e-02 | -3.70 | epithelial tube branching involved in lung morphogenesis | biological process | GO:0060441 | 25 | 8 | 16441 | 2455 |
CTNNB1,TMTC3,FGFR2,SOX9,CTSZ,DAG1,SPRY2,FOXA1 |
| 2.475e-02 | -3.70 | negative regulation of dendrite development | biological process | GO:2000171 | 25 | 8 | 16441 | 2455 |
PTEN,CIT,PLK2,RAPGEF2,KIAA0319,EFNA1,ARF6,NGEF |
| 2.475e-02 | -3.70 | positive regulation of tissue remodeling | biological process | GO:0034105 | 25 | 8 | 16441 | 2455 |
SPP1,CA2,IL15,BAX,IL18,TMEM64,SYK,TMBIM1 |
| 2.475e-02 | -3.70 | glucan biosynthetic process | biological process | GO:0009250 | 25 | 8 | 16441 | 2455 |
PGM1,UGP2,AKT1,PGM2L1,GYS1,PHKG2,EPM2A,PER2 |
| 2.475e-02 | -3.70 | regulation of microtubule depolymerization | biological process | GO:0031114 | 25 | 8 | 16441 | 2455 |
GAS2L1,MID1IP1,CKAP2,AURKA,AURKB,HDAC6,CCNB1,APC2 |
| 2.475e-02 | -3.70 | positive regulation of ion transport | biological process | GO:0043270 | 226 | 45 | 16441 | 2455 |
PRSS8,SCN5A,TCAF1,PINK1,LGALS3,ATP8A1,CALM3,PKP2,P2RX7,PDGFB,KIF5B,CALM2,ADORA1,STIM1,DPYSL2,PLCG2,SGK3,DLG1,DNM2,BAX,SGK1,TRPC1,CACNA1D,F2R,HSPA2,CHP1,P2RX4,RAB3B,CASK,AKT1,CALM1,ANO6,ATP1B1,PLCG1,HTT,WFS1,MYLK,PKD2,STK39,GPER1,FHL1,ATP1B3,JAK3,TRPC3,DRD1 |
| 2.480e-02 | -3.70 | HDL cholesterol(PMID:21909109) | GWAS genes | HDL cholesterol(PMID:21909109) | 5 | 3 | 2389 | 350 |
OAS3,PVRL2,ABCA1 |
| 2.480e-02 | -3.70 | BIOCARTA_NOS1_PATHWAY | MSigDB lists | BIOCARTA_NOS1_PATHWAY | 21 | 7 | 17758 | 2588 |
CALM2,CALM3,GRIN2D,PRKAR2B,CALM1,GRIN1,PRKAR1A |
| 2.480e-02 | -3.70 | BIOCARTA_TFF_PATHWAY | MSigDB lists | BIOCARTA_TFF_PATHWAY | 21 | 7 | 17758 | 2588 |
RHOA,AKT1,CTNNB1,EGFR,CASP9,PIK3R1,PIK3CA |
| 2.480e-02 | -3.70 | VERRECCHIA_RESPONSE_TO_TGFB1_C5 | MSigDB lists | VERRECCHIA_RESPONSE_TO_TGFB1_C5 | 21 | 7 | 17758 | 2588 |
EFNA5,ILK,CTNNB1,ITGB8,DDR1,SMO,FGD1 |
| 2.480e-02 | -3.70 | BIOCARTA_MITOCHONDRIA_PATHWAY | MSigDB lists | BIOCARTA_MITOCHONDRIA_PATHWAY | 21 | 7 | 17758 | 2588 |
CASP3,CASP7,BCL2L1,CASP9,BIK,XIAP,BAX |
| 2.480e-02 | -3.70 | FOURNIER_ACINAR_DEVELOPMENT_LATE_DN | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_LATE_DN | 21 | 7 | 17758 | 2588 |
AURKA,TUBG1,DUSP4,SERPINE2,FOXM1,ASPM,CKS2 |
| 2.480e-02 | -3.70 | PID_S1P_S1P1_PATHWAY | MSigDB lists | PID_S1P_S1P1_PATHWAY | 21 | 7 | 17758 | 2588 |
PTGS2,PLCG1,RHOA,ITGAV,PLCB2,PDGFB,ABCC1 |
| 2.480e-02 | -3.70 | MOOTHA_GLYCOGEN_METABOLISM | MSigDB lists | MOOTHA_GLYCOGEN_METABOLISM | 21 | 7 | 17758 | 2588 |
PPP1CB,GYS1,PYGL,GAA,PPP1CA,PHKA2,PPP1R2 |
| 2.482e-02 | -3.70 | - | gene3d domains | 3.40.50.850 | 2 | 2 | 9988 | 1574 |
ISOC2,ISOC1 |
| 2.482e-02 | -3.70 | - | gene3d domains | 3.90.1170.50 | 2 | 2 | 9988 | 1574 |
XDH,AOX1 |
| 2.482e-02 | -3.70 | - | gene3d domains | 3.30.170.10 | 2 | 2 | 9988 | 1574 |
CKS1B,CKS2 |
| 2.482e-02 | -3.70 | - | gene3d domains | 3.30.365.10 | 2 | 2 | 9988 | 1574 |
AOX1,XDH |
| 2.482e-02 | -3.70 | - | gene3d domains | 1.10.150.120 | 2 | 2 | 9988 | 1574 |
AOX1,XDH |
| 2.482e-02 | -3.70 | DDENN | prosite domains | PS50947 | 16 | 6 | 11866 | 1802 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 2.482e-02 | -3.70 | ALDEHYDE_DEHYDR_GLU | prosite domains | PS00687 | 16 | 6 | 11866 | 1802 |
ALDH7A1,ALDH3B1,ALDH5A1,ALDH2,ALDH3A2,ALDH1A3 |
| 2.482e-02 | -3.70 | DENN | prosite domains | PS50211 | 16 | 6 | 11866 | 1802 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 2.482e-02 | -3.70 | ALDEHYDE_DEHYDR_CYS | prosite domains | PS00070 | 16 | 6 | 11866 | 1802 |
ALDH3B1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 2.482e-02 | -3.70 | GUANYLATE_KINASE_1 | prosite domains | PS00856 | 16 | 6 | 11866 | 1802 |
MPP5,CASK,DLG3,MPP1,MPP2,DLG1 |
| 2.482e-02 | -3.70 | UDENN | prosite domains | PS50946 | 16 | 6 | 11866 | 1802 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 2.488e-02 | -3.69 | HOOI_ST7_TARGETS_UP | MSigDB lists | HOOI_ST7_TARGETS_UP | 82 | 19 | 17758 | 2588 |
ANXA3,PCGF5,ACACB,RUNX2,KIAA1462,IL15,RGMB,CDA,ISOC2,MEST,RBP7,ENDOD1,IL6ST,IL31RA,LHX6,INPP4B,CPLX1,CYP2U1,FHL1 |
| 2.488e-02 | -3.69 | MODULE_40 | MSigDB lists | MODULE_40 | 82 | 19 | 17758 | 2588 |
PCCB,FADS2,ALDH6A1,CPT2,CYP2J2,HAL,ASL,MGST2,OAT,IDH1,ALDH5A1,AGPAT2,PLCG2,GOT1,ALDH7A1,ACOX2,PLD1,ACADM,FAH |
| 2.488e-02 | -3.69 | LEE_AGING_CEREBELLUM_UP | MSigDB lists | LEE_AGING_CEREBELLUM_UP | 82 | 19 | 17758 | 2588 |
LGALS3,TBC1D1,NR4A1,DNAJB2,HEXB,CTSZ,FOS,GNB2,LGALS3BP,SNTA1,CAPN2,SIPA1L2,SPP1,TGFBR3,AXL,IRF7,IFIT1,CTSD,RAD21 |
| 2.490e-02 | -3.69 | cellular response to abiotic stimulus | biological process | GO:0071214 | 267 | 52 | 16441 | 2455 |
SLC2A4,CTSB,CUL4B,SOX9,HABP4,SWI5,TP53,CALM3,BCL2L1,TP73,CALM2,PCNA,GNB5,DNM2,BAX,CRY2,CNGA1,SCN2A,RPGR,EEF1D,METAP2,CHP1,SIRT1,DDB2,AKT1,FIGNL1,PBK,CALM1,PIK3R1,CASP9,PTGER4,PRKCQ,AURKB,CD40,ELK1,GNA11,RHOB,NMT2,FAS,BCL10,KDM4D,GPLD1,RGS9,PTGS2,ATP1A1,FNTA,MYLK,CAB39,SERPINB6,PKD2,STK39,IRF1 |
| 2.490e-02 | -3.69 | B cell receptor signaling pathway | KEGG pathways | ko04662 | 72 | 18 | 6908 | 1076 |
INPPL1,AKT1,NFKBIE,INPP5D,PIK3R1,CR2,RASGRP3,FOS,BCL10,RAC2,PIK3AP1,CD22,NFKBIA,PLCG2,PIK3CA,PIK3CD,CD81,SYK |
| 2.490e-02 | -3.69 | B cell receptor signaling pathway | KEGG pathways | hsa04662 | 72 | 18 | 6908 | 1076 |
INPPL1,AKT1,NFKBIE,INPP5D,PIK3R1,CR2,RASGRP3,FOS,BCL10,RAC2,PIK3AP1,CD22,NFKBIA,PLCG2,PIK3CA,PIK3CD,CD81,SYK |
| 2.492e-02 | -3.69 | SQSTM1 (sequestosome 1) | protein interactions | 8878 | 202 | 43 | 16036 | 2547 |
LGALS3,EPAS1,TRIM5,TP53,CUL1,PSMD10,TGFBR1,CCNB1,HDAC6,MAP1LC3B,RAD23A,IRAK1,LLGL2,CEP78,PSMC2,PIK3CA,PRKCI,TRIM21,EGLN3,DVL2,EEF1D,DNAI1,MAP3K3,MBP,ARHGEF28,PIK3R1,CASP9,CALM1,ZFAND5,SESN1,CDK1,ULK2,DCP2,OPTN,FAS,GABARAPL1,ENPP1,INSR,HTT,PSMD3,NOD2,CTNND1,HSPB1 |
| 2.494e-02 | -3.69 | GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1) | protein interactions | 8729 | 28 | 9 | 16036 | 2547 |
LYPD3,PNPLA2,RABL6,HDAC6,PNKD,NUP85,EGFR,VCP,COPG1 |
| 2.494e-02 | -3.69 | ETS2 (v-ets avian erythroblastosis virus E26 oncogene homolog 2) | protein interactions | 2114 | 28 | 9 | 16036 | 2547 |
NCOA3,ETS2,NR3C1,TP53,GATA3,TWIST1,ETS1,FOS,ZFYVE9 |
| 2.494e-02 | -3.69 | RRM2 (ribonucleotide reductase M2) | protein interactions | 6241 | 28 | 9 | 16036 | 2547 |
PLK1,INPPL1,FAF2,CDH1,DNM1L,TP53,CCNF,PPP2R5D,CDK1 |
| 2.494e-02 | -3.69 | SAAL1 (serum amyloid A-like 1) | protein interactions | 113174 | 28 | 9 | 16036 | 2547 |
P2RX4,USH1C,SHROOM3,CD274,SCARA3,PNKD,ALDH3A2,EGFR,CD33 |
| 2.495e-02 | -3.69 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | 196 | 39 | 17758 | 2588 |
DDX58,SERPINE2,TRIM5,TAP1,TEX2,FAM81A,DUSP5,RAC2,PSMD1,OXCT1,ELMO2,MGAT4A,KCNS3,IRF2,BUB1,AURKB,F12,RAB38,ASB13,PRKRA,RNF19B,RNPEP,ANTXR1,NIN,AMZ2,NUCB1,TAPBP,TRAM2,CASP7,AREG,CCDC6,NLRC5,AURKA,IRF7,CHMP4B,STK39,CMPK2,CBX5,UBE2C |
| 2.497e-02 | -3.69 | MAPK12 (mitogen-activated protein kinase 12) | protein interactions | 6300 | 37 | 11 | 16036 | 2547 |
SNTA1,MBP,RGS3,DLG1,MAPK13,ERBB2IP,SNTB1,DLG3,PKN1,DUSP1,MAPK12 |
| 2.497e-02 | -3.69 | PSAT1 (phosphoserine aminotransferase 1) | protein interactions | 29968 | 37 | 11 | 16036 | 2547 |
DAZAP1,MPRIP,HSPG2,STAT6,PSMD10,CAB39,TAGLN2,PCBP1,HSPB1,ARF4,SGPL1 |
| 2.497e-02 | -3.69 | GAB1 (GRB2-associated binding protein 1) | protein interactions | 2549 | 37 | 11 | 16036 | 2547 |
MAP3K3,PLCG1,INSR,PTPN18,INPP5D,PLCG2,RET,PIK3R1,PRKCI,MAPK4,EGFR |
| 2.497e-02 | -3.69 | PPL (periplakin) | protein interactions | 5493 | 37 | 11 | 16036 | 2547 |
SUSD3,PSMB4,RBM24,AKT1,RALBP1,TRAF2,P4HA2,EZR,CUL1,RAB3IP,PSMA5 |
| 2.500e-02 | -3.69 | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP | 161 | 33 | 17758 | 2588 |
CEP70,KLHL13,ITGA6,ASB9,NUCB2,FAM101B,DDR1,SNX9,CHST2,SCML1,CYHR1,HSF2,IGF1R,DACT1,IL6ST,OCRL,TPCN1,CD55,MPP1,BNIP3L,ZSCAN12,SLC11A2,MEST,STK17A,SERTAD2,RIN3,EFNA1,CEP41,HOOK1,APBA2,SAT2,SNPH,FAM134B |
| 2.502e-02 | -3.69 | ATPASE_ACTIVITY_COUPLED | MSigDB lists | ATPASE_ACTIVITY_COUPLED | 93 | 21 | 17758 | 2588 |
RECQL,PEX6,RALBP1,SMARCAL1,ABCG2,VPS4B,DHX8,PIF1,ATP1B1,ABCD4,DDX23,TOP2A,TAPBP,ATP1A1,ATP7B,ATP8B1,ATP1B3,ATP6V1C1,ATP2B1,ABCG1,ABCC1 |
| 2.505e-02 | -3.69 | platelet dense granule membrane | cellular component | GO:0031088 | 5 | 3 | 17570 | 2579 |
LAMP2,CD63,ITPR1 |
| 2.505e-02 | -3.69 | lateral loop | cellular component | GO:0043219 | 5 | 3 | 17570 | 2579 |
ERBB2,MPP5,DLG1 |
| 2.505e-02 | -3.69 | chromosome passenger complex | cellular component | GO:0032133 | 5 | 3 | 17570 | 2579 |
AURKA,AURKB,CDCA8 |
| 2.506e-02 | -3.69 | ependymoma | COSMIC cancer mutations | ependymoma | 173 | 35 | 17775 | 2585 |
NF2,RASA2,TP53,MORF4L2,TP73,ZFYVE16,RBM23,CTNNB1,NOXA1,PTEN,MKRN3,FRYL,ATP13A3,MAP3K9,PIK3CA,GYS1,RTKN2,ESPN,RP2,PIKFYVE,MAP3K7,TGIF1,AKT1,HN1L,SYNE2,TEP1,CCBL2,ROR1,IDH1,EGFR,HLA-B,ARHGAP4,CCNB2,ZC3HC1,XDH |
| 2.508e-02 | -3.69 | Amphetamine addiction | KEGG pathways | ko05031 | 67 | 17 | 6908 | 1076 |
SIRT1,CALM1,GRIN1,CALM3,PRKACA,FOS,GNAS,CALM2,FOSB,MAOA,HDAC1,PPP1CB,GRIN2D,CACNA1D,PPP1CA,CAMK2G,DRD1 |
| 2.508e-02 | -3.69 | Amphetamine addiction | KEGG pathways | hsa05031 | 67 | 17 | 6908 | 1076 |
SIRT1,CALM1,GRIN1,CALM3,PRKACA,FOS,GNAS,CALM2,FOSB,MAOA,HDAC1,PPP1CB,GRIN2D,CACNA1D,PPP1CA,CAMK2G,DRD1 |
| 2.509e-02 | -3.69 | Oxoglu/Fe-dep_dioxygenase | interpro domains | IPR005123 | 21 | 7 | 18293 | 2672 |
PLOD3,EGLN3,PLOD2,P3H2,P4HA2,P4HA3,EGLN1 |
| 2.509e-02 | -3.69 | GDS_CDC24_CS | interpro domains | IPR001331 | 21 | 7 | 18293 | 2672 |
RASGRF1,ARHGEF3,TIAM1,ARHGEF7,MCF2L,ABR,ARHGEF4 |
| 2.509e-02 | -3.69 | Pept_cys_AS | interpro domains | IPR000169 | 21 | 7 | 18293 | 2672 |
CTSL,CAPN2,CAPN12,CTSC,CTSB,CTSV,CAPN1 |
| 2.511e-02 | -3.68 | Hedgehog ligand biogenesis | REACTOME pathways | R-HSA-5358346 | 64 | 16 | 8202 | 1235 |
ADAM17,ERLEC1,PSMB4,PSME2,PSMD7,PSMD10,PSME1,NOTUM,PSMA4,VCP,PSMD1,P4HB,PSMD3,PSMC2,PSMC1,PSMA5 |
| 2.512e-02 | -3.68 | CASP3 (caspase 3) | protein interactions | 836 | 175 | 38 | 16036 | 2547 |
PLA2G4A,CASP3,ADD1,CAST,PTTG1,XIAP,IL18,PKN1,BCAP31,PSIP1,NEO1,RB1,WEE1,CTNNB1,CDH1,PAK2,TFAP2A,BAX,CTTN,SOCS5,ATG4D,KCNIP3,AKT1,PLEKHO1,CASP9,PDE5A,PRKCQ,ARHGDIB,BCAR1,CASP4,RASA1,NMT2,TNS4,FYN,CASP7,HTT,STAT1,HSPB1 |
| 2.520e-02 | -3.68 | CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | MSigDB lists | CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 121 | 26 | 17758 | 2588 |
POU6F1,PDGFC,MBP,PAX6,UGT8,JRKL,PBX3,NCKAP1,DNER,GSTP1,HPCAL4,CDK5R1,FOXP2,ALDH5A1,CTNS,PTEN,SHC3,LHX6,SERPINI1,ARNT2,SOX8,DRP2,SHROOM2,ALDH3A2,RPS6KA3,JARID2 |
| 2.522e-02 | -3.68 | DGAT2 (diacylglycerol O-acyltransferase 2) | protein interactions | 84649 | 2 | 2 | 16036 | 2547 |
AMFR,VCP |
| 2.522e-02 | -3.68 | CST7 (cystatin F (leukocystatin)) | protein interactions | 8530 | 2 | 2 | 16036 | 2547 |
CTSL,CTSB |
| 2.522e-02 | -3.68 | Sod1 (superoxide dismutase 1, soluble) | protein interactions | 20655 | 2 | 2 | 16036 | 2547 |
SOD1,DNAJB2 |
| 2.522e-02 | -3.68 | CFAP57 (cilia and flagella associated protein 57) | protein interactions | 149465 | 2 | 2 | 16036 | 2547 |
FOS,TRAF2 |
| 2.522e-02 | -3.68 | NUDT22 (nudix hydrolase 22) | protein interactions | 84304 | 2 | 2 | 16036 | 2547 |
AES,LHX6 |
| 2.522e-02 | -3.68 | H2AFJ (H2A histone family, member J) | protein interactions | 55766 | 2 | 2 | 16036 | 2547 |
VCP,RAD21 |
| 2.522e-02 | -3.68 | TPO (thyroid peroxidase) | protein interactions | 7173 | 2 | 2 | 16036 | 2547 |
DUOX1,TXNDC11 |
| 2.522e-02 | -3.68 | SIGLEC9 (sialic acid binding Ig-like lectin 9) | protein interactions | 27180 | 2 | 2 | 16036 | 2547 |
NCAM1,LGALS3BP |
| 2.522e-02 | -3.68 | LIF (leukemia inhibitory factor) | protein interactions | 3976 | 2 | 2 | 16036 | 2547 |
LIFR,IL6ST |
| 2.522e-02 | -3.68 | Pik3r1 (phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)) | protein interactions | 18708 | 2 | 2 | 16036 | 2547 |
CBL,SH3KBP1 |
| 2.522e-02 | -3.68 | Ywhaq (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide) | protein interactions | 22630 | 2 | 2 | 16036 | 2547 |
RGS3,CALM1 |
| 2.522e-02 | -3.68 | IL17B (interleukin 17B) | protein interactions | 27190 | 2 | 2 | 16036 | 2547 |
IL17RB,ENO2 |
| 2.522e-02 | -3.68 | Cbl (Cbl proto-oncogene, E3 ubiquitin protein ligase) | protein interactions | 500985 | 2 | 2 | 16036 | 2547 |
F2RL1,SH3KBP1 |
| 2.522e-02 | -3.68 | SORCS1 (sortilin-related VPS10 domain containing receptor 1) | protein interactions | 114815 | 2 | 2 | 16036 | 2547 |
SORT1,FURIN |
| 2.522e-02 | -3.68 | anapc11 (anaphase promoting complex subunit 11) | protein interactions | 496247 | 2 | 2 | 16036 | 2547 |
UBE2C,UBE2D2 |
| 2.522e-02 | -3.68 | RGS7BP (regulator of G-protein signaling 7 binding protein) | protein interactions | 401190 | 2 | 2 | 16036 | 2547 |
RGS9,GNB5 |
| 2.522e-02 | -3.68 | ERMAP (erythroblast membrane-associated protein (Scianna blood group)) | protein interactions | 114625 | 2 | 2 | 16036 | 2547 |
NADK2,VASP |
| 2.522e-02 | -3.68 | Tnfrsf8 (tumor necrosis factor receptor superfamily, member 8) | protein interactions | 25069 | 2 | 2 | 16036 | 2547 |
TRAF5,TRAF2 |
| 2.522e-02 | -3.68 | GPER1 (G protein-coupled estrogen receptor 1) | protein interactions | 2852 | 2 | 2 | 16036 | 2547 |
PTEN,PTTG1 |
| 2.522e-02 | -3.68 | ADGRA3 (adhesion G protein-coupled receptor A3) | protein interactions | 166647 | 2 | 2 | 16036 | 2547 |
DLG1,RYK |
| 2.522e-02 | -3.68 | CYP2A6 (cytochrome P450, family 2, subfamily A, polypeptide 6) | protein interactions | 1548 | 2 | 2 | 16036 | 2547 |
POR,CYB5A |
| 2.522e-02 | -3.68 | ABHD17B (abhydrolase domain containing 17B) | protein interactions | 51104 | 2 | 2 | 16036 | 2547 |
FAF2,A4GALT |
| 2.522e-02 | -3.68 | fzr1 (fizzy/cell division cycle 20 related 1) | protein interactions | 380351 | 2 | 2 | 16036 | 2547 |
CCNB1,UBE2C |
| 2.522e-02 | -3.68 | CYP1A2 (cytochrome P450, family 1, subfamily A, polypeptide 2) | protein interactions | 1544 | 2 | 2 | 16036 | 2547 |
POR,CYB5A |
| 2.522e-02 | -3.68 | CDHR1 (cadherin-related family member 1) | protein interactions | 92211 | 2 | 2 | 16036 | 2547 |
PROM1,RYK |
| 2.522e-02 | -3.68 | NUDT7 (nudix hydrolase 7) | protein interactions | 283927 | 2 | 2 | 16036 | 2547 |
CUL1,PEX5 |
| 2.522e-02 | -3.68 | PPEF2 (protein phosphatase, EF-hand calcium binding domain 2) | protein interactions | 5470 | 2 | 2 | 16036 | 2547 |
CALM3,CALM1 |
| 2.522e-02 | -3.68 | HEG1 (heart development protein with EGF-like domains 1) | protein interactions | 57493 | 2 | 2 | 16036 | 2547 |
LGALS3,LGALS8 |
| 2.522e-02 | -3.68 | UBC4 (E2 ubiquitin-conjugating protein UBC4) | protein interactions | 852376 | 2 | 2 | 16036 | 2547 |
TRIM21,HTT |
| 2.522e-02 | -3.68 | PPP1CA (protein phosphatase 1, catalytic subunit, alpha isozyme) | protein interactions | 516175 | 2 | 2 | 16036 | 2547 |
RB1,RBL1 |
| 2.522e-02 | -3.68 | MAOA (monoamine oxidase A) | protein interactions | 4128 | 2 | 2 | 16036 | 2547 |
MAOA,NDRG1 |
| 2.522e-02 | -3.68 | NEIL3 (nei-like DNA glycosylase 3) | protein interactions | 55247 | 2 | 2 | 16036 | 2547 |
TWIST1,TP53 |
| 2.522e-02 | -3.68 | CYP4A11 (cytochrome P450, family 4, subfamily A, polypeptide 11) | protein interactions | 1579 | 2 | 2 | 16036 | 2547 |
CYB5A,PIK3R1 |
| 2.522e-02 | -3.68 | FAIM (Fas apoptotic inhibitory molecule) | protein interactions | 55179 | 2 | 2 | 16036 | 2547 |
SPRY2,XIAP |
| 2.522e-02 | -3.68 | Traf3 (TNF receptor-associated factor 3) | protein interactions | 22031 | 2 | 2 | 16036 | 2547 |
CD40,TNFRSF19 |
| 2.522e-02 | -3.68 | AJAP1 (adherens junctions associated protein 1) | protein interactions | 55966 | 2 | 2 | 16036 | 2547 |
CTNNB1,CDH1 |
| 2.522e-02 | -3.68 | Stx8 (syntaxin 8) | protein interactions | 55943 | 2 | 2 | 16036 | 2547 |
TGFBR1,ACVR1 |
| 2.522e-02 | -3.68 | IFIT1B (interferon-induced protein with tetratricopeptide repeats 1B) | protein interactions | 439996 | 2 | 2 | 16036 | 2547 |
IFIT1,IFIT3 |
| 2.522e-02 | -3.68 | PPP1R2P3 (protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3) | protein interactions | 153743 | 2 | 2 | 16036 | 2547 |
PPP1CB,PPP1CA |
| 2.522e-02 | -3.68 | Diaph1 (diaphanous related formin 1) | protein interactions | 13367 | 2 | 2 | 16036 | 2547 |
PAX6,RHOA |
| 2.522e-02 | -3.68 | Srsf1 (serine/arginine-rich splicing factor 1) | protein interactions | 110809 | 2 | 2 | 16036 | 2547 |
TRAF5,TRAF2 |
| 2.522e-02 | -3.68 | AP5Z1 (adaptor-related protein complex 5, zeta 1 subunit) | protein interactions | 9907 | 2 | 2 | 16036 | 2547 |
IRF2,MDFI |
| 2.522e-02 | -3.68 | IL31RA (interleukin 31 receptor A) | protein interactions | 133396 | 2 | 2 | 16036 | 2547 |
LIFR,IL6ST |
| 2.522e-02 | -3.68 | XAGE3 (X antigen family, member 3) | protein interactions | 170626 | 2 | 2 | 16036 | 2547 |
GMCL1,HTT |
| 2.522e-02 | -3.68 | Aif1 (allograft inflammatory factor 1) | protein interactions | 11629 | 2 | 2 | 16036 | 2547 |
LCP1,PLS3 |
| 2.522e-02 | -3.68 | Ppp1cc (protein phosphatase 1, catalytic subunit, gamma isoform) | protein interactions | 19047 | 2 | 2 | 16036 | 2547 |
CALM1,SH3KBP1 |
| 2.522e-02 | -3.68 | RSPO3 (R-spondin 3) | protein interactions | 84870 | 2 | 2 | 16036 | 2547 |
ZNRF3,LGR4 |
| 2.522e-02 | -3.68 | Tnfrsf14 (tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)) | protein interactions | 230979 | 2 | 2 | 16036 | 2547 |
TRAF5,TRAF2 |
| 2.522e-02 | -3.68 | ADGRA2 (adhesion G protein-coupled receptor A2) | protein interactions | 25960 | 2 | 2 | 16036 | 2547 |
DLG1,RYK |
| 2.522e-02 | -3.68 | COL5A2 (collagen, type V, alpha 2) | protein interactions | 1290 | 2 | 2 | 16036 | 2547 |
DDR1,BMP1 |
| 2.522e-02 | -3.68 | FAM109A (family with sequence similarity 109, member A) | protein interactions | 144717 | 2 | 2 | 16036 | 2547 |
PLEKHJ1,OCRL |
| 2.522e-02 | -3.68 | ZBTB37 (zinc finger and BTB domain containing 37) | protein interactions | 84614 | 2 | 2 | 16036 | 2547 |
HSPB1,SH3BP4 |
| 2.522e-02 | -3.68 | PDE5A (phosphodiesterase 5A, cGMP-specific) | protein interactions | 8654 | 2 | 2 | 16036 | 2547 |
CASP3,PRKG1 |
| 2.522e-02 | -3.68 | Plek (pleckstrin) | protein interactions | 56193 | 2 | 2 | 16036 | 2547 |
TGFBR1,ACVR1 |
| 2.522e-02 | -3.68 | Sorbs1 (sorbin and SH3 domain containing 1) | protein interactions | 20411 | 2 | 2 | 16036 | 2547 |
CBL,PRKAA1 |
| 2.522e-02 | -3.68 | HTA1 (histone H2A) | protein interactions | 851811 | 2 | 2 | 16036 | 2547 |
ACTR8,PPP2R4 |
| 2.522e-02 | -3.68 | pcn1 (DNA polymerase delta processivity factor) | protein interactions | 2540020 | 2 | 2 | 16036 | 2547 |
PCNA,POLD3 |
| 2.522e-02 | -3.68 | RGPD4 (RANBP2-like and GRIP domain containing 4) | protein interactions | 285190 | 2 | 2 | 16036 | 2547 |
PLK1,LGR4 |
| 2.522e-02 | -3.68 | Eef1a1 (eukaryotic translation elongation factor 1 alpha 1) | protein interactions | 13627 | 2 | 2 | 16036 | 2547 |
RGS12,CALM1 |
| 2.522e-02 | -3.68 | ZNF239 (zinc finger protein 239) | protein interactions | 8187 | 2 | 2 | 16036 | 2547 |
CEP70,LMNA |
| 2.522e-02 | -3.68 | NAT16 (N-acetyltransferase 16 (GCN5-related, putative)) | protein interactions | 375607 | 2 | 2 | 16036 | 2547 |
RIPK2,NOD2 |
| 2.522e-02 | -3.68 | Cacnb3 (calcium channel, voltage-dependent, beta 3 subunit) | protein interactions | 25297 | 2 | 2 | 16036 | 2547 |
PAX6,MAP1LC3B |
| 2.522e-02 | -3.68 | BRRF1 (putative BRRF1 protein) | protein interactions | 3783728 | 2 | 2 | 16036 | 2547 |
NFKB2,TRAF2 |
| 2.522e-02 | -3.68 | Stat5b (signal transducer and activator of transcription 5B) | protein interactions | 20851 | 2 | 2 | 16036 | 2547 |
INSR,CENPJ |
| 2.522e-02 | -3.68 | CD207 (CD207 molecule, langerin) | protein interactions | 50489 | 2 | 2 | 16036 | 2547 |
SUSD3,SCARA3 |
| 2.522e-02 | -3.68 | HYAL4 (hyaluronoglucosaminidase 4) | protein interactions | 23553 | 2 | 2 | 16036 | 2547 |
TP53,IARS2 |
| 2.522e-02 | -3.68 | SPG11 (spastic paraplegia 11 (autosomal recessive)) | protein interactions | 80208 | 2 | 2 | 16036 | 2547 |
AP5M1,SERTAD3 |
| 2.522e-02 | -3.68 | Papss1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) | protein interactions | 23971 | 2 | 2 | 16036 | 2547 |
PAPSS2,PAPSS1 |
| 2.522e-02 | -3.68 | NOCT (nocturnin) | protein interactions | 25819 | 2 | 2 | 16036 | 2547 |
FAF2,PLAUR |
| 2.522e-02 | -3.68 | Usp21 (ubiquitin specific peptidase 21) | protein interactions | 30941 | 2 | 2 | 16036 | 2547 |
TGFBR1,ACVR1 |
| 2.522e-02 | -3.68 | ZNF568 (zinc finger protein 568) | protein interactions | 374900 | 2 | 2 | 16036 | 2547 |
ILK,CBX5 |
| 2.522e-02 | -3.68 | Wasl (Wiskott-Aldrich syndrome-like (human)) | protein interactions | 73178 | 2 | 2 | 16036 | 2547 |
BIN1,SH3KBP1 |
| 2.523e-02 | -3.68 | Ubiquitin-rel_dom | interpro domains | IPR029071 | 184 | 37 | 18293 | 2672 |
FRMPD3,ARAP3,FAF2,FARP1,FRMD4A,NF2,FRMD6,DGKQ,RASSF7,MAP1LC3B,RAD23A,RASSF8,RGS12,FBXO7,PIK3CA,ZFAND4,DIXDC1,EPB41L4B,PIK3CD,TECR,TLN2,MYLIP,DVL2,FARP2,EPB41L5,TCEB2,RAPGEF2,SHARPIN,NUB1,EZR,UBAC1,GABARAPL1,FRMD4B,YOD1,PIK3C2B,EPB41L4A,RGS14 |
| 2.524e-02 | -3.68 | PI3K/AKT Signaling in Cancer | REACTOME pathways | R-HSA-2219528 | 85 | 20 | 8202 | 1235 |
AKT1,NR4A1,CASP9,PIK3R1,NRG2,ERBB2,PDGFB,FGF19,EGFR,IRS2,PDGFA,FYN,FGFR2,FGF18,PIK3CA,CDKN1B,NRG1,ERBB3,PIK3CD,GAB1 |
| 2.526e-02 | -3.68 | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | COSMIC cancer mutations | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | 678 | 117 | 17775 | 2585 |
MTM1,PPP4R4,GRHL2,LGR4,PAPSS2,ARFGEF1,TP53,P2RX7,VARS2,CAMK1D,ITPR2,SLC7A2,SNX9,TMC1,DENND2D,CYP39A1,ZNF385B,SLC9A7,SH3KBP1,GRM5,DAPK2,MUC16,CTNNB1,SP100,PAPSS1,ANKFN1,MITF,PIK3CA,DAB2IP,PDE4D,SCN2A,ZNF365,CPE,MCTP1,UTRN,CDCA2,PRKCQ,KIF13A,LDB2,TANC1,PPP1R14C,IDH1,ALCAM,DOCK5,EBF2,OSBPL2,TRAM2,STAT6,NOD2,MAOA,NRG1,GLA,GLCCI1,COBL,ARNT,FAM134B,PRKAR1A,DENND5B,DDX58,RUNX2,LRRFIP2,PARP14,TBC1D1,ATP9A,ITGA6,ABCG2,GABRG2,SELL,PBX3,SLC36A4,CNTNAP2,INTS8,DNAH3,ANO1,ZDHHC21,CD109,BMP2,CA2,ITGB8,PIK3AP1,ARSG,FAM189A1,CTSC,GPC3,MAP3K9,KIAA0319,PRKG1,CACNA1D,RPGR,MYO5A,CHSY3,RGMB,PARD3B,MRS2,SYBU,FBXO8,MAML2,ZSCAN12,KDM3A,ANTXR1,EGFR,BSDC1,PDE11A,TXK,KLHL2,FECH,PLEKHH2,PRKAG2,SYT7,TBX18,C1orf21,AMMECR1,ALPK3,GRAMD1C,ATP6V1C1,SEMA3A,DOCK9 |
| 2.535e-02 | -3.68 | RasGEF | smart domains | SM00147 | 28 | 9 | 9131 | 1455 |
BCAR3,RASGRF1,RALGPS2,SH2D3C,RAPGEF2,RASGRP3,RASGEF1A,RASGRP1,RASGRP2 |
| 2.538e-02 | -3.67 | Ald_Xan_dh_C | smart domains | SM01008 | 2 | 2 | 9131 | 1455 |
AOX1,XDH |
| 2.538e-02 | -3.67 | CKS | smart domains | SM01084 | 2 | 2 | 9131 | 1455 |
CKS1B,CKS2 |
| 2.538e-02 | -3.67 | CO_deh_flav_C | smart domains | SM01092 | 2 | 2 | 9131 | 1455 |
AOX1,XDH |
| 2.540e-02 | -3.67 | Galactosemia | SMPDB pathways | SMP00182 | 13 | 6 | 978 | 190 |
AKR1B1,PGM1,GALK1,GAA,GLA,UGP2 |
| 2.540e-02 | -3.67 | Galactose Metabolism | SMPDB pathways | SMP00043 | 13 | 6 | 978 | 190 |
AKR1B1,PGM1,GALK1,GAA,GLA,UGP2 |
| 2.544e-02 | -3.67 | KDR (kinase insert domain receptor) | protein interactions | 3791 | 56 | 15 | 16036 | 2547 |
PLCG1,FYN,TIMP3,CTNNB1,IQGAP1,PLCG2,STAT1,DNM2,CUL1,COL18A1,YES1,PLXNA1,CBL,GNA11,RASA1 |
| 2.544e-02 | -3.67 | GRIN1 (glutamate receptor, ionotropic, N-methyl D-aspartate 1) | protein interactions | 2902 | 56 | 15 | 16036 | 2547 |
PLCG1,FYN,CTNNB1,MAP2,CIT,CALM1,GRIN1,GRIN2D,EPHB4,DUSP4,DLG3,TIAM1,RPS6KA3,CAMK2G,DRD1 |
| 2.549e-02 | -3.67 | V$IK3_01 | MSigDB lists | V$IK3_01 | 214 | 42 | 17758 | 2588 |
BCAM,ARAP3,FRMD4A,TSC22D3,GATA3,EGR3,APBA1,SRPX2,NAPG,PDCD10,CYR61,PRICKLE3,SLC44A1,TFAP2A,ADAM15,SNX16,RGS5,TINAGL1,OSBPL7,MYT1,HCN3,HN1L,VAMP3,RGAG1,CD40,PNKD,FOS,TIMP3,NFKBIA,AMMECR1,MADD,PPP1CB,FAM117A,SERPINI1,SH3BGRL2,SP6,GRAMD1C,WDR62,ARPC2,SEMA3A,LIFR,PTGES |
| 2.559e-02 | -3.67 | SAM | interpro domains | IPR001660 | 93 | 21 | 18293 | 2672 |
ARAP3,ARAP2,INPPL1,EPHA4,PPFIBP2,SAMD9,EPHA1,SCML1,EPHA10,TP73,DGKH,ANKS6,ANKS1B,STIM1,DDHD2,ARAP1,SFMBT1,SAMD8,EPHB4,STARD13,PHC1 |
| 2.564e-02 | -3.66 | IRAK1 (interleukin 1 receptor associated kinase 1) | protein interactions | 3654 | 122 | 28 | 16036 | 2547 |
MAP3K3,SIGIRR,UNC93B1,MBP,PINK1,ST13,AKT1,RIPK2,ADCK3,SLC25A13,CUL1,PELI3,HLA-A,LMNA,BCL10,RCN1,IL1R1,VASP,ATP1A1,IRAK1,PELI2,STAT1,PRKCI,IRF7,MAP3K7,HSPB1,IL1RAP,TMEM173 |
| 2.570e-02 | -3.66 | human chr1q32.1 | chromosome location | human chr1q32.1 | 89 | 16 | 26250 | 2805 |
TMCC2,DYRK3,PLEKHA6,ASCL5,ZC3H11A,SLC41A1,GOLT1A,C1orf116,UBE2T,ADORA1,LRRN2,KIF14,ADIPOR1,LEMD1,DDX59,SLC45A3 |
| 2.570e-02 | -3.66 | Znf_RING/FYVE/PHD | interpro domains | IPR013083 | 438 | 79 | 18293 | 2672 |
EXPH5,RNF224,TRIM2,TRIM24,TRIM5,RNF182,SYTL4,PJA2,HDAC6,BARD1,TRIM68,PHF1,ZFYVE9,SYTL2,ZFYVE16,CYHR1,RNF220,SP100,MKRN3,MARCH2,RNF26,MYRIP,RNF169,VPS11,PCGF5,TRIM8,ING1,RNF11,RNF165,PYGO1,CBL,RNF19B,TRIM7,JADE1,TRIM9,TRIM47,PEX2,TRIM45,TRAF5,FGD1,RMND5A,SHPRH,TRAF2,CBLL1,ZNRF3,SH3RF2,MARCH8,DTX3L,WDFY1,MLPH,PHF7,RNF128,ZNRF2,TRIM3,PLEKHF1,TRIM21,RAG1,PIKFYVE,MYLIP,SYTL3,TRIM62,RIMS2,PHF20L1,LONRF3,AMFR,RC3H2,WHSC1,TRIM35,RNF113A,NEURL1B,JADE2,G2E3,TRIM69,DTX4,FGD6,FHL1,ZMIZ1,RNF146,USP16 |
| 2.571e-02 | -3.66 | pancreas-carcinoma-acinar_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-acinar_carcinoma | 2069 | 331 | 17775 | 2585 |
DOC2A,TRIM24,HSPG2,IBTK,OAT,DPP8,BARD1,GRM5,CHST2,EPDR1,RGS12,MUC4,DNAH6,ZFP36,RGS3,IQCE,TMEM37,SPEF2,KIFC2,CDA,RNF19B,PLCG1,C17orf51,AREG,ATP7B,MYLK,SEMA6B,MRC2,INPPL1,FAM169A,DHPS,TBC1D1,TMTC3,CYP2J2,ITGA6,KIF23,TXNDC9,NOTCH2,PSIP1,LMNA,DOPEY2,RALGPS2,CD22,SLC16A6,MSH2,FBXL14,SORL1,TNFRSF12A,STT3B,CACNA1D,PANX2,ZMYM1,MOXD1,MYLIP,KCTD3,TSPAN33,DNAI1,IGSF3,KCNJ12,SLC37A1,ZNF84,STAT4,SHARPIN,GLT8D2,FRMD4B,DHX32,PLEKHH2,HTT,FAAH,MATN2,APPL2,ARAP1,DYSF,PCDH19,CABIN1,CBX5,TRPC3,ADAMTS16,EHD1,PKD1L2,CCDC109B,CERCAM,IRX4,PKP2,FAM91A1,APPBP2,APLP2,MUC16,SCNN1A,ACAP2,TRANK1,FICD,EPHB4,SLC5A11,SEC61B,COL6A2,CAPN6,UTRN,TEP1,CDCA2,NUSAP1,C15orf39,TANC1,ALCAM,POPDC3,CCNB3,JAK1,SLC27A1,HS3ST3B1,ARNT,ATMIN,PRKAR1A,ANKRD13D,TNRC6C,DEPDC1,PLEKHJ1,BTN3A1,PBX3,ANO9,KCNC4,DNAH3,TSPAN17,HOXB2,ICAM1,CKAP5,AKIRIN1,ZFX,SLC25A45,ANK1,FUT2,IGSF9,PHF7,ANKS1B,PTEN,MGAT1,TUBGCP6,BAX,ATP8B1,ADAM15,ERBB3,RAG1,CNOT6L,TTPA,SPRY2,MED22,SMC4,AMOTL2,ADAMTS2,PCCB,RASGRF1,ARHGEF28,LCA5,CXorf57,PGBD1,RAB3IP,RGS9,PROM1,MAMDC4,RCBTB2,FGFR2,RIN3,FHL1,WDR62,SLC25A38,FOXA1,SRSF9,RGMA,LTBP1,UGT8,PPM1J,EPHX4,UBE2Q1,DNAJB11,MPP5,TRIM68,SH3KBP1,CHPF,CPNE2,BTG3,TM9SF2,CTNNB1,NPNT,ABCA2,DLG1,DUSP10,NTN4,CTTN,MYH14,PXMP4,TECR,MYBL1,NEB,IL1RAP,TRIM8,MARK1,CELSR2,ASXL1,SYNE3,NFE2L1,EZR,ESYT1,VCP,KDM4D,TRIM9,ZNF114,GPRC5B,KCNK1,ZNF367,MADD,CCDC74B,ARRDC1,CTNND1,ADIPOR1,APBA2,TC2N,PM20D2,SAMD9,CNTNAP2,PHLPP1,B4GALNT1,RB1,KIAA0895,IGF1R,SPIN4,FRAS1,ICAM5,KIF13B,EBF4,LIMCH1,AHCY,PIM1,FAR2,LRIF1,ALS2CL,CCDC88A,ABCC1,PCBP3,CORO2A,PARD3B,SPATA13,GYLTL1B,BTN3A2,EIF2AK1,KIAA1109,HEATR5A,IFIT3,ZDHHC3,EGFR,G2E3,C18orf8,NMT2,MUM1L1,GNAS,ITGA7,SLC2A6,ALPK3,CTSA,DONSON,LTBP2,KIF12,SHROOM2,GAS2L1,UGP2,TP53,COL18A1,CYP26A1,SAP130,KHNYN,EFR3A,ZDHHC12,PLCG2,NOTCH3,ECE1,TMEM64,LOXL1,SUSD3,TMTC1,KREMEN2,RFK,ATP13A2,HSF4,PTGS2,PAFAH1B3,TLE1,PLXND1,SYT13,AKNA,REEP4,LIFR,CMTM4,PACSIN2,TAB3,COL4A5,INTS8,JAG2,VPS26A,SH2D4A,SIRPA,HDAC9,CD109,SNX13,ZDHHC13,NFE2L3,PHF20L1,DCAF6,NR3C1,SYBU,PRICKLE1,TTC7A,COL7A1,RUNX3,AKAP3,NDRG3,BCAR1,FOXL1,DGKE,LEMD2,KLHL2,CNOT2,ARHGAP24,ENDOD1,CASP7,FAT4,FGF18,TMC5,CSGALNACT1,ATP6V1C1,GEM,ZMIZ1,PKIA,GOLGB1 |
| 2.571e-02 | -3.66 | acinar_carcinoma | COSMIC cancer mutations | acinar_carcinoma | 2069 | 331 | 17775 | 2585 |
DOC2A,TRIM24,HSPG2,IBTK,OAT,DPP8,BARD1,GRM5,CHST2,EPDR1,RGS12,MUC4,DNAH6,ZFP36,RGS3,IQCE,TMEM37,SPEF2,KIFC2,CDA,RNF19B,PLCG1,C17orf51,AREG,ATP7B,MYLK,SEMA6B,MRC2,INPPL1,FAM169A,DHPS,TBC1D1,TMTC3,CYP2J2,ITGA6,KIF23,TXNDC9,NOTCH2,PSIP1,LMNA,DOPEY2,RALGPS2,CD22,SLC16A6,MSH2,FBXL14,SORL1,TNFRSF12A,STT3B,CACNA1D,PANX2,ZMYM1,MOXD1,MYLIP,KCTD3,TSPAN33,DNAI1,IGSF3,KCNJ12,SLC37A1,ZNF84,STAT4,SHARPIN,GLT8D2,FRMD4B,DHX32,PLEKHH2,HTT,FAAH,MATN2,APPL2,ARAP1,DYSF,PCDH19,CABIN1,CBX5,TRPC3,ADAMTS16,EHD1,PKD1L2,CCDC109B,CERCAM,IRX4,PKP2,FAM91A1,APPBP2,APLP2,MUC16,SCNN1A,ACAP2,TRANK1,FICD,EPHB4,SLC5A11,SEC61B,COL6A2,CAPN6,UTRN,TEP1,CDCA2,NUSAP1,C15orf39,TANC1,ALCAM,POPDC3,CCNB3,JAK1,SLC27A1,HS3ST3B1,ARNT,ATMIN,PRKAR1A,ANKRD13D,TNRC6C,DEPDC1,PLEKHJ1,BTN3A1,PBX3,ANO9,KCNC4,DNAH3,TSPAN17,HOXB2,ICAM1,CKAP5,AKIRIN1,ZFX,SLC25A45,ANK1,FUT2,IGSF9,PHF7,ANKS1B,PTEN,MGAT1,TUBGCP6,BAX,ATP8B1,ADAM15,ERBB3,RAG1,CNOT6L,TTPA,SPRY2,MED22,SMC4,AMOTL2,ADAMTS2,PCCB,RASGRF1,ARHGEF28,LCA5,CXorf57,PGBD1,RAB3IP,RGS9,PROM1,MAMDC4,RCBTB2,FGFR2,RIN3,FHL1,WDR62,SLC25A38,FOXA1,SRSF9,RGMA,LTBP1,UGT8,PPM1J,EPHX4,UBE2Q1,DNAJB11,MPP5,TRIM68,SH3KBP1,CHPF,CPNE2,BTG3,TM9SF2,CTNNB1,NPNT,ABCA2,DLG1,DUSP10,NTN4,CTTN,MYH14,PXMP4,TECR,MYBL1,NEB,IL1RAP,TRIM8,MARK1,CELSR2,ASXL1,SYNE3,NFE2L1,EZR,ESYT1,VCP,KDM4D,TRIM9,ZNF114,GPRC5B,KCNK1,ZNF367,MADD,CCDC74B,ARRDC1,CTNND1,ADIPOR1,APBA2,TC2N,PM20D2,SAMD9,CNTNAP2,PHLPP1,B4GALNT1,RB1,KIAA0895,IGF1R,SPIN4,FRAS1,ICAM5,KIF13B,EBF4,LIMCH1,AHCY,PIM1,FAR2,LRIF1,ALS2CL,CCDC88A,ABCC1,PCBP3,CORO2A,PARD3B,SPATA13,GYLTL1B,BTN3A2,EIF2AK1,KIAA1109,HEATR5A,IFIT3,ZDHHC3,EGFR,G2E3,C18orf8,NMT2,MUM1L1,GNAS,ITGA7,SLC2A6,ALPK3,CTSA,DONSON,LTBP2,KIF12,SHROOM2,GAS2L1,UGP2,TP53,COL18A1,CYP26A1,SAP130,KHNYN,EFR3A,ZDHHC12,PLCG2,NOTCH3,ECE1,TMEM64,LOXL1,SUSD3,TMTC1,KREMEN2,RFK,ATP13A2,HSF4,PTGS2,PAFAH1B3,TLE1,PLXND1,SYT13,AKNA,REEP4,LIFR,CMTM4,PACSIN2,TAB3,COL4A5,INTS8,JAG2,VPS26A,SH2D4A,SIRPA,HDAC9,CD109,SNX13,ZDHHC13,NFE2L3,PHF20L1,DCAF6,NR3C1,SYBU,PRICKLE1,TTC7A,COL7A1,RUNX3,AKAP3,NDRG3,BCAR1,FOXL1,DGKE,LEMD2,KLHL2,CNOT2,ARHGAP24,ENDOD1,CASP7,FAT4,FGF18,TMC5,CSGALNACT1,ATP6V1C1,GEM,ZMIZ1,PKIA,GOLGB1 |
| 2.573e-02 | -3.66 | V$PAX4_02 | MSigDB lists | V$PAX4_02 | 226 | 44 | 17758 | 2588 |
PAX6,CPEB4,CAST,TSC22D3,MIER3,IRX4,TGFBR1,RAB6A,DOCK11,SYTL2,FOXP2,RNF128,RALGPS2,PPP1R10,ZDHHC12,PPP1R16A,MITF,DIXDC1,TACSTD2,BTBD3,PLEKHA6,CXXC5,ELK3,TBC1D8B,SAT1,MBNL3,RGAG1,CYFIP2,LDB2,PPP1R14C,EBF2,MAP1B,NFIX,ARHGAP24,PITX2,SLC4A4,ITGA7,ARRB1,ZMIZ1,SEMA3A,CDAN1,TOB1,HOXC13,JARID2 |
| 2.573e-02 | -3.66 | V$E2F_Q3_01 | MSigDB lists | V$E2F_Q3_01 | 226 | 44 | 17758 | 2588 |
ARHGAP11A,IER5L,GATA3,EGR3,NRP2,WEE1,E2F7,PCNA,ZNF687,FAM160A2,BMP7,RANBP1,TNPO2,USP1,MXD3,STT3B,PIM1,OSBPL7,CITED2,STK35,DDB2,ADAMTS2,UFD1L,UXT,FBXO9,ERBB2IP,PKMYT1,KDM3A,CDK1,TRIM47,DCK,ZNF367,HOXA9,E2F1,AGFG2,KLF5,HMGA1,WDR62,CBX5,GEN1,NR3C2,E2F8,MELK,HS6ST3 |
| 2.575e-02 | -3.66 | cleavage furrow | cellular component | GO:0032154 | 45 | 12 | 17570 | 2579 |
PLEKHG6,RHOA,NF2,SSH1,SEPT6,MYLK,PLK4,RACGAP1,PKN1,NDE1,ARF6,RHOB |
| 2.575e-02 | -3.66 | cell surface furrow | cellular component | GO:0097610 | 45 | 12 | 17570 | 2579 |
PLEKHG6,RHOA,NF2,SSH1,SEPT6,MYLK,PLK4,RACGAP1,PKN1,NDE1,ARF6,RHOB |
| 2.581e-02 | -3.66 | V$FOXO1_01 | MSigDB lists | V$FOXO1_01 | 232 | 45 | 17758 | 2588 |
IER5L,BIN1,LASP1,BMF,CDKN1C,CHCHD7,THRA,NDRG1,ETV5,ARFGEF1,ZNF385B,SCML1,FOXP2,CCND1,SESN3,CYR61,LMO4,MITF,WBP4,PLCB2,DUSP1,CXXC5,TRIM8,ASXL1,RGAG1,C2orf69,LRRC1,ITPR3,KDM3A,H2AFV,NFIB,NFIX,CRTC2,PITX2,TSC1,CAMK2N2,TBC1D17,KLF12,PPP1CB,NR4A2,EIF4EBP2,NRG1,C1orf43,OSR1,NR2C2 |
| 2.583e-02 | -3.66 | mammary gland development | biological process | GO:0030879 | 124 | 27 | 16441 | 2455 |
AKT1,SOX9,ERBB2,TFAP2C,SCRIB,DDR1,ELF3,IRS2,CCND1,NCOA3,IGF1R,AREG,FGFR2,STAT6,HOXA9,CSF1,ATP7B,ELF5,SMO,NRG1,NTN1,WNT3A,USF2,SLC12A2,ETV4,CAPN1,XDH |
| 2.591e-02 | -3.65 | Assembly of collagen fibrils and other multimeric structures | REACTOME pathways | R-HSA-2022090 | 54 | 14 | 8202 | 1235 |
CTSL,COL6A2,PCOLCE,CTSB,ITGA6,CTSV,COL6A1,BMP1,COL18A1,COL4A5,COL7A1,LOXL2,LOXL1,TLL2 |
| 2.592e-02 | -3.65 | V$PAX2_02 | MSigDB lists | V$PAX2_02 | 244 | 47 | 17758 | 2588 |
LASP1,TRIM2,FRMD4A,POC1B,ETV5,CACNA2D2,TGFBR1,MPP5,BAHD1,DNER,SLC20A1,DHRS3,SDC1,HOXB2,PER2,CCND1,FOXP2,SESN3,RNF220,SLC16A6,PRICKLE3,GPC3,VASN,BCL6,TSPAN13,ETHE1,WBP4,CITED2,TRIM8,RHOA,ELK3,CDC20,RNF11,UBE2A,DUSP4,CD40,FOS,GLT8D2,NFIB,EGFR,EPN3,CAMK2N2,NFKBIA,SERPINI1,CTNND1,OSR1,TOB1 |
| 2.593e-02 | -3.65 | REACTOME_INNATE_IMMUNE_SYSTEM | MSigDB lists | REACTOME_INNATE_IMMUNE_SYSTEM | 268 | 51 | 17758 | 2588 |
DDX58,OTUD5,SIGIRR,UNC93B1,TXN,HSP90B1,LGALS3,NLRX1,TAB3,CTSB,TRAF2,RPS6KA1,P2RX7,HERC5,BCL2L1,CD46,RPS6KA2,IRAK1,PLCG2,DNM2,IRF2,MAPK11,MAP3K7,LGMN,MAPK7,NFKB2,CNPY3,CD55,RIPK2,MAPKAPK3,CASP9,PELI3,DUSP4,ELK1,FOS,CDK1,CASP4,MAPKAPK2,DDOST,PELI2,NFKBIA,UBE2D2,NLRC5,NOD2,IRF7,MAPK13,IFIH1,PPP2R5D,RPS6KA3,IRF1,MAPK12 |
| 2.595e-02 | -3.65 | ADRM1 (adhesion regulating molecule 1) | protein interactions | 11047 | 61 | 16 | 16036 | 2547 |
MX1,PSMB4,PSMD7,PSMD10,PSME1,PSMA4,EGFR,RAD23A,CCDC92,PSMD1,PSMD3,PSMC2,CCDC74B,RPN2,PSMC1,PSMA5 |
| 2.596e-02 | -3.65 | oxidoreductase activity, acting on superoxide radicals as acceptor | molecular function | GO:0016721 | 5 | 3 | 16491 | 2452 |
SOD1,NQO1,SOD2 |
| 2.596e-02 | -3.65 | steroid hormone binding | molecular function | GO:1990239 | 5 | 3 | 16491 | 2452 |
ATP1A1,GPER1,NR3C1 |
| 2.596e-02 | -3.65 | molybdopterin cofactor binding | molecular function | GO:0043546 | 5 | 3 | 16491 | 2452 |
MARC1,XDH,AOX1 |
| 2.596e-02 | -3.65 | superoxide dismutase activity | molecular function | GO:0004784 | 5 | 3 | 16491 | 2452 |
SOD1,NQO1,SOD2 |
| 2.596e-02 | -3.65 | CD4 receptor binding | molecular function | GO:0042609 | 5 | 3 | 16491 | 2452 |
PLSCR4,FYN,PLSCR1 |
| 2.596e-02 | -3.65 | cupric reductase activity | molecular function | GO:0008823 | 5 | 3 | 16491 | 2452 |
STEAP3,STEAP1,STEAP2 |
| 2.596e-02 | -3.65 | ferric-chelate reductase (NADPH) activity | molecular function | GO:0052851 | 5 | 3 | 16491 | 2452 |
STEAP3,STEAP1,STEAP2 |
| 2.597e-02 | -3.65 | liposaccharide metabolic process | biological process | GO:1903509 | 113 | 25 | 16441 | 2455 |
PIGC,UGT8,PLAUR,HEXB,ASAH1,NANS,ARSK,PIGL,CPTP,PGAP1,B4GALNT1,GPLD1,ALDH5A1,ITGB8,ARSG,A4GALT,BAX,GLB1,CTSA,GLA,ARSB,ST3GAL1,NAGA,GM2A,KDELC2 |
| 2.597e-02 | -3.65 | glycoprotein binding | molecular function | GO:0001948 | 97 | 22 | 16491 | 2452 |
ERLEC1,AGRN,CTSB,GYLTL1B,FBXO2,ERBB2,FBXO6,SDC1,DAG1,RASA1,PTPRF,CALR,CTSL,FYN,IDE,ITGA3,CDH1,SERPINA1,MAP2,GPC3,FBXO27,RGMA |
| 2.597e-02 | -3.65 | BRSK2 (BR serine/threonine kinase 2) | protein interactions | 9024 | 8 | 4 | 16036 | 2547 |
WEE1,CDC25C,PRKAA1,VCP |
| 2.597e-02 | -3.65 | CREG1 (cellular repressor of E1A-stimulated genes 1) | protein interactions | 8804 | 8 | 4 | 16036 | 2547 |
RB1,FBXO6,RBL1,CAPN1 |
| 2.597e-02 | -3.65 | LILRB1 (leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1) | protein interactions | 10859 | 8 | 4 | 16036 | 2547 |
HLA-B,HLA-C,HLA-F,HLA-A |
| 2.597e-02 | -3.65 | FASTKD5 (FAST kinase domains 5) | protein interactions | 60493 | 8 | 4 | 16036 | 2547 |
UNC93B1,MAPK4,FBXO6,NLRX1 |
| 2.597e-02 | -3.65 | Nedd4 (neural precursor cell expressed, developmentally down-regulated 4) | protein interactions | 17999 | 8 | 4 | 16036 | 2547 |
SCN5A,GUCD1,N4BP3,SCN3A |
| 2.597e-02 | -3.65 | SLA2 (Src-like-adaptor 2) | protein interactions | 84174 | 8 | 4 | 16036 | 2547 |
ERBB2,CBL,CSF1,EGFR |
| 2.597e-02 | -3.65 | CDK10 (cyclin-dependent kinase 10) | protein interactions | 8558 | 8 | 4 | 16036 | 2547 |
PLS1,RNASEH2A,FAM84B,ETS2 |
| 2.597e-02 | -3.65 | NDST2 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2) | protein interactions | 8509 | 8 | 4 | 16036 | 2547 |
RCN1,HLA-E,PLAUR,SDF4 |
| 2.597e-02 | -3.65 | SP6 (Sp6 transcription factor) | protein interactions | 80320 | 8 | 4 | 16036 | 2547 |
SORL1,GNB2,C18orf8,DNAAF3 |
| 2.597e-02 | -3.65 | MPP2 (membrane protein, palmitoylated 2) | protein interactions | 4355 | 8 | 4 | 16036 | 2547 |
CUL1,PLK1,ERBB2IP,DLG1 |
| 2.597e-02 | -3.65 | SOCS4 (suppressor of cytokine signaling 4) | protein interactions | 122809 | 8 | 4 | 16036 | 2547 |
MDFIC,TCEB2,NR4A1,EGFR |
| 2.597e-02 | -3.65 | ADCY9 (adenylate cyclase 9) | protein interactions | 115 | 8 | 4 | 16036 | 2547 |
LGALS3,LGALS8,HSPB1,AREG |
| 2.597e-02 | -3.65 | C12orf43 (chromosome 12 open reading frame 43) | protein interactions | 64897 | 8 | 4 | 16036 | 2547 |
FAM177A1,CDK17,SPC25,SLC30A6 |
| 2.597e-02 | -3.65 | ITM2C (integral membrane protein 2C) | protein interactions | 81618 | 8 | 4 | 16036 | 2547 |
MVB12B,BACE1,FURIN,RYK |
| 2.597e-02 | -3.65 | ARMC9 (armadillo repeat containing 9) | protein interactions | 80210 | 8 | 4 | 16036 | 2547 |
DPP8,CTSC,PRPS2,CRTAP |
| 2.597e-02 | -3.65 | BGLAP (bone gamma-carboxyglutamate (gla) protein) | protein interactions | 632 | 8 | 4 | 16036 | 2547 |
RB1,CTSD,CBX5,CTSB |
| 2.597e-02 | -3.65 | RPS26P11 (ribosomal protein S26 pseudogene 11) | protein interactions | 441502 | 8 | 4 | 16036 | 2547 |
CUL1,IGSF8,ICAM1,RAD21 |
| 2.597e-02 | -3.65 | REN (renin) | protein interactions | 5972 | 8 | 4 | 16036 | 2547 |
KCTD15,CTSB,M6PR,PCSK5 |
| 2.597e-02 | -3.65 | ALCAM (activated leukocyte cell adhesion molecule) | protein interactions | 214 | 8 | 4 | 16036 | 2547 |
LGALS3,ALCAM,LGALS8,EGFR |
| 2.597e-02 | -3.65 | SIX3 (SIX homeobox 3) | protein interactions | 6496 | 8 | 4 | 16036 | 2547 |
TLE1,AES,PAX6,NR4A3 |
| 2.597e-02 | -3.65 | Gorasp1 (golgi reassembly stacking protein 1) | protein interactions | 74498 | 8 | 4 | 16036 | 2547 |
LRRFIP2,KIF14,LGALS3BP,TMED2 |
| 2.597e-02 | -3.65 | HIST1H2BM (histone cluster 1, H2bm) | protein interactions | 8342 | 8 | 4 | 16036 | 2547 |
IGSF8,CD81,SPRTN,ICAM1 |
| 2.597e-02 | -3.65 | HIVEP3 (human immunodeficiency virus type I enhancer binding protein 3) | protein interactions | 59269 | 8 | 4 | 16036 | 2547 |
WWP1,FHL1,RUNX2,TRAF2 |
| 2.597e-02 | -3.65 | LILRB2 (leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2) | protein interactions | 10288 | 8 | 4 | 16036 | 2547 |
HLA-B,HLA-C,HLA-F,HLA-A |
| 2.597e-02 | -3.65 | EMILIN3 (elastin microfibril interfacer 3) | protein interactions | 90187 | 8 | 4 | 16036 | 2547 |
ERLEC1,SCARA3,PLAUR,PASK |
| 2.597e-02 | -3.65 | UFSP2 (UFM1-specific peptidase 2) | protein interactions | 55325 | 8 | 4 | 16036 | 2547 |
FAM177A1,HLA-C,CAPN1,FAS |
| 2.597e-02 | -3.65 | TAS2R41 (taste receptor, type 2, member 41) | protein interactions | 259287 | 8 | 4 | 16036 | 2547 |
LASP1,NIPSNAP3A,SCRN2,SEPHS1 |
| 2.598e-02 | -3.65 | ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) | protein interactions | 25 | 208 | 44 | 16036 | 2547 |
BIN1,SORBS1,INPPL1,UBASH3B,TP53,ERBB2,SORBS3,BCL2L1,REPS1,SLC9A2,BMP2K,SH3KBP1,TP73,RB1,ST5,PCNA,CTNNB1,SH3BP1,PAK2,ADAM15,CDKN1B,ERBB3,PDE4D,CKAP4,DDB2,PTPN18,MBP,PLSCR1,PIK3R1,CASP9,CBL,BCAR1,FOS,CDK1,PSMA4,RASA1,EGFR,SOCS3,PLCG1,NCOA3,JAK1,NFKBIA,GRIN2D,LRRK1 |
| 2.600e-02 | -3.65 | - | gene3d domains | 3.30.500.10 | 24 | 8 | 9988 | 1574 |
HLA-B,MICB,HLA-F,HLA-E,RAET1L,HLA-C,ULBP2,HLA-A |
| 2.603e-02 | -3.65 | Ion transport by P-type ATPases | REACTOME pathways | R-HSA-936837 | 49 | 13 | 8202 | 1235 |
ATP1A1,ATP9A,ATP7B,ATP8A1,FXYD3,ATP2C2,ATP8B1,ATP8B3,ATP1B1,ATP1B3,ATP10D,ATP2B1,ATP13A2 |
| 2.603e-02 | -3.65 | EFh | smart domains | SM00054 | 143 | 32 | 9131 | 1455 |
MYL9,SLC25A24,SLC25A13,CALB2,DGKA,CALM3,EFHD2,RASGRP3,NUCB2,HPCAL4,NCS1,SDF4,PLS3,CALM2,RCN1,CAPN2,CABP1,DGKG,CHP1,GCA,KCNIP3,CALM1,PLS1,CAPNS1,MYL12A,LCP1,RASGRP2,PLCH1,DUOX1,NUCB1,CGREF1,CAPN1 |
| 2.605e-02 | -3.65 | IQ | pfam domains | PF00612 | 44 | 12 | 16629 | 2504 |
MYO5B,LOC100996693,ASPM,IQGAP1,IQCE,SPA17,IQCD,MYH14,IQGAP3,NRGN,MYO5A,MYO5C |
| 2.609e-02 | -3.65 | Downstream TCR signaling | REACTOME pathways | R-HSA-202424 | 96 | 22 | 8202 | 1235 |
PSMB4,RIPK2,PSME2,INPP5D,PIK3R1,PSMD7,PSMD10,CUL1,PRKCQ,PSME1,PSMA4,BCL10,PSMD1,PTEN,PSMD3,NFKBIA,PSMC2,UBE2D2,PIK3CA,MAP3K7,PSMC1,PSMA5 |
| 2.610e-02 | -3.65 | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN | 179 | 36 | 17758 | 2588 |
UGP2,IL15RA,SDC4,SOD2,IL18,CD274,SLC1A3,ICAM1,RND1,IER3,ZFX,BTG3,E2F7,ITGB8,PIK3AP1,SNX18,DRAM1,MSH6,RIPK2,TNIP1,RAPGEF2,PIM3,SAV1,RNF19B,CDK1,SOCS3,CD83,PTGS2,PTPRJ,TMEM54,NFKBIA,SLC2A6,RAP2C,ARRB1,NFKBIZ,EHD1 |
| 2.610e-02 | -3.65 | GSE3982_DC_VS_MAC_UP | MSigDB lists | GSE3982_DC_VS_MAC_UP | 179 | 36 | 17758 | 2588 |
FARP1,FAF2,LRRFIP2,UGP2,DAP,ARL4C,ABCG2,CBLL1,TRIB2,HDAC9,SLC25A36,CCDC92,PDGFA,MAGOHB,RAB15,ENTPD4,DNPEP,RIMS3,SERINC2,OPN3,TACSTD2,RFX5,IGSF3,LAMP3,NFE2L3,ING1,ADCK3,CTNNAL1,CORO2A,FHL2,TRAM2,PAFAH1B3,C19orf66,SETD3,NR4A3,ANXA11 |
| 2.615e-02 | -3.64 | proteolysis | biological process | GO:0006508 | 1143 | 194 | 16441 | 2455 |
CASP3,KLK10,FAF2,DNAJC3,CUL4B,RET,FBXO2,CUL1,UBE2Z,PSME1,CCNB1,DPP8,HDAC6,PSMD1,P4HB,PSMC2,TINAGL1,CPE,ERAP2,METAP2,PLK1,FBXL16,TNIP1,ASXL1,LAP3,ITCH,USP18,CASP9,RNF11,RNF165,KLK6,AURKB,F12,CCNF,RNF19B,TYSND1,CDK1,VCP,TRIM9,BMP1,PSMC1,CAPN1,PCSK5,PRSS8,DNAJB2,PSMD7,ZNRF3,ADAMTSL4,ATG4A,OTUD1,DNPEP,FBXO7,NEK2,FBXL14,PCYOX1,USP1,USP38,STT3B,CTSD,ZRANB1,MYLIP,DESI2,PSMA5,PMPCB,UFD1L,KLK5,PRSS23,USP31,FBXO8,BCL2L13,CYFIP2,TP53INP2,PSMA4,FBXO10,NMT2,FAS,MMP15,NUDT16,OTUD6B,AGBL5,AURKA,YOD1,KLK7,CTSA,RNF146,XDH,ADAMTS16,USP43,FBXW5,CAPN12,ST14,PSME2,RHBDL3,PTTG1,P2RX7,PRSS22,MVB12B,TMPRSS4,ZFYVE9,RAD23A,CD46,KIF14,CDKN1B,ECE1,LGMN,EGLN3,F2R,ATG4D,CPD,SIRT1,GCA,SEC61B,ERMP1,ERLEC1,CAPN6,CDC20,VPS4B,PRKCQ,SLC11A2,CBL,XRCC6BP1,DAG1,CASP4,ZMPSTE24,AMZ2,DNAJC10,IDE,NGFRAP1,WFS1,PSMD3,MMP17,WWTR1,ADAMTS14,TRABD2A,CHMP4B,AREL1,LTA4H,OTUD5,PINK1,NKX3-1,HSP90B1,PCOLCE,DAP,BACE1,CIT,TRAF2,CTSB,JKAMP,PDIA3,PSMD10,CTSZ,FBXO6,DNAJB9,WWP2,CAPN2,CARD8,RNF128,CTSC,ALG13,UBE2J1,BAX,ADAM15,WWP1,ADAMTS2,ADAM17,PSMB4,LONRF3,CFAP46,AMFR,NUB1,UBE2A,FURIN,DPP9,FBXO9,GGH,CAPNS1,RNPEP,SCRN2,USP6,CTSL,CASP7,ATXN7L3,PRCP,CTSV,UBE2D2,ERAP1,ARRB1,OTUB2,SPCS3,NDFIP1,UBE2C,ESPL1,USP16,TLL2 |
| 2.619e-02 | -3.64 | metabolic process | biological process | GO:0008152 | 9879 | 1519 | 16441 | 2455 |
AK7,SLC25A13,PNPLA2,HEXB,RET,CCNO,TRAPPC8,ISOC2,LACTB2,DPP8,SPSB1,GRM5,ZNF275,PHYHIP,MUC4,UBE2T,ATP13A3,DNM2,CRY2,PPP1CA,WBP4,TIPARP,CPE,MGAT5,NEK4,FBXL16,UXT,CDA,KDELR3,TFAP2C,PRKAR2B,RNF19B,PNKD,ARF4,GINS4,PIAS3,ENPP1,PLCG1,MID1IP1,CELF5,ATP7B,NOD2,HDAC1,RNASEL,ITPKA,HSPB1,GGA1,SEC61G,COX6C,RABGGTA,ATG4A,MARCH8,TFAP4,FLII,RAC2,ZCCHC17,ATP5H,RIMS3,FBXO7,FBXL14,PCYOX1,MAP3K9,USP38,USP1,ALPK1,MYDGF,MAPK7,MOXD1,DGKG,MYLIP,NUP85,PHKG2,TTLL1,PPP6R1,MCCC2,REC8,PQLC3,MAPKAPK3,PYM1,ERO1A,SHARPIN,FHL2,KIF20B,ELK1,NPHP3,DPYSL4,PCTP,GOLT1A,PSMA4,GNA11,FNTA,ETS2,APMAP,DGAT2,STK39,CFAP20,NUP58,RUSC1,ADAMTS16,DMPK,NQO1,LFNG,INPP5D,RHBDL3,PTTG1,MAPK4,GRK6,MGST2,MVB12B,MOCS1,RBM23,MUC16,XYLT2,ENPP5,DLG3,RASGEF1A,MYT1,ETV4,MX1,SEC61B,ERMP1,COL6A2,RIPK2,APOBEC3D,AGPS,PFKFB2,PTPN9,SAT1,VPS4B,HTATIP2,XRCC6BP1,GTF2A2,ZNF618,COX20,EBF2,GABARAPL1,NFIX,ALDH3B1,CDK19,WFS1,AXL,PNPLA6,PRIMA1,ISOC1,MAPK12,HSP90B1,GCAT,BACE1,TRAF2,DCAF7,ESRP1,CCM2,SDC4,HABP4,OSGIN2,CTSZ,PLPPR4,ZNF219,HDGFRP2,NFAT5,SGPL1,DIRAS3,ZFX,FUT2,ITGB8,GPC3,TMEM62,MGAT4A,FAM20B,CST3,KLC3,BAX,IGFBP2,RAG1,MED22,PARP9,ACBD5,OPLAH,ADAMTS2,PLSCR1,PIK3R1,DUSP23,NUB1,UBE2A,AK4,PIM3,LDLRAP1,RPL12,PLOD2,SLC35B3,DBI,PLA2G15,PPM1H,NR4A3,ITGAV,CMPK2,OSR1,CD81,WDR45B,SRSF9,ACOT7,PHC1,TLL2,TNK1,EPAS1,CNOT8,LMCD1,PHOSPHO1,DNAJB11,TEX2,ITPR2,MGAT5B,GALM,SPTB,FANCI,TFAP2E,INPP5E,ENTPD4,RPS6KA2,NUP210,CTNNB1,P4HB,IL6ST,ARL1,PAPSS1,PSMC2,PAPL,SLC44A1,MITF,PASK,ABCA2,PLK1,THRB,KCNIP3,MARK1,PTPN18,CBX6,NFE2L1,CR2,CCBL2,EAF2,SESN1,TRUB1,KDM4D,TRIM9,HS6ST1,TRAM2,PI4K2B,AGPAT2,KLF12,ZNF367,HOXA9,KLF11,KPNA2,HS6ST3,RRAGD,PRSS8,RUNX2,LMTK3,PARP12,LGALS3,DNAJB2,RASA2,PSMD7,ADCK5,RAB6A,HES2,FBLN1,RSAD1,B4GALNT1,MYO5C,UBE2Q2,KIF13B,TBCD,SLC30A6,AHCY,PIM1,FAR2,CKAP4,DPYSL5,USP31,MGAT4B,ZNF320,STRADB,ZSCAN12,PDK3,BCL2L13,NMT2,CDK5R1,FOXD2,FA2H,COL13A1,OTUD6B,PHLPP2,KBTBD2,P4HA3,ZDHHC7,FAM213A,PLD1,USP43,RAD21,HOXB7,CTDSPL,TMX4,TP53,P2RX7,BAHD1,PCBP1,PDGFA,KMT5C,LMO4,PPME1,BCL6,PLK4,ZDHHC23,VAT1,GLB1L2,NOTCH3,OAS3,LMAN1,CTDSP2,SULF2,PPIF,ERLEC1,AKT1,SERTAD3,PTGER4,ACO1,DAG1,ATP13A2,PTGS2,ZNF628,TAPBP,PTPRJ,IDE,PAFAH1B3,ABHD12,RBL1,MMP17,STK38,MAOA,CHMP4B,XRCC3,IRF7,ST3GAL1,CTDSP1,CMAS,PINK1,DYRK3,CPEB4,TAB3,KLHL13,CTSB,SCD5,HAL,GNAL,ERCC6L,ERI2,GTF3A,LBR,AIP,DNAJB9,ZDHHC21,FOXP2,CDK16,ALPP,GTF2F2,UBE2J1,TFAP2A,SGK1,TRIM21,ALDH7A1,HMGCL,SYK,ATP2B1,GCNT1,DUSP1,NFE2L3,P2RX4,HES1,RHOA,HMGN5,GUSB,PLAUR,DPP9,MAML2,GGH,COL7A1,RNPEP,DGKE,USP6,BCL10,DDX23,CNOT2,DDAH1,SCG2,NEIL3,FGF18,E2F1,PTGES,HIPK3,ZBTB33,CFAP61,SLC35D2,TXN,SSH1,HSPG2,TMEM86B,CUL1,PSME1,NANS,CAMK1D,PJA2,OAT,PICK1,ASPHD2,PAK6,TYMP,HELZ2,CYP1A1,ZNF823,PALD1,FOSB,POLL,KCNS3,SERINC2,PIK3CA,IRF2,MARCH2,ZBTB18,METAP2,SPATA18,ACVR1C,CDYL,BNIP3L,SLC35C1,KIF13A,POR,PRIM1,GDE1,SH2D3C,PPP2R4,PRDM5,BMP1,MAPK13,NFKBIZ,WBSCR27,RECQL,MRC2,CDKN1C,DHPS,TMEM55B,PRKAA1,AKAP17A,HERC6,TNFRSF19,PDXDC1,PSIP1,SH3RF2,CALR,ZNRF2,BHLHE41,RPL39,PPP4R1,MSH2,DAPK1,TPST1,ADCK2,PRKG1,CACNA1D,MAST4,ZNF117,SOCS5,TRAK2,PIGC,SPATA20,GFPT1,PRODH,KLK5,PRSS23,ADCK3,LPGAT1,CALM1,WHSC1,PYGL,NPC2,EPHA1,ATP8B3,JADE2,NFIB,PDE11A,MMP15,SLCO4A1,NT5C2,FAAH,PELI2,ZDHHC20,AGBL5,PIAS2,MPP2,SFMBT1,KLK7,CDK18,SAMD8,ZBTB34,PER3,IFIH1,SPRED1,KIF3C,FOXO6,TCF25,DLGAP5,CAPN12,ST14,THRA,ATP2C2,FTH1,FLT3,DDR1,CYP39A1,ART5,ZFYVE9,EPM2A,APOBEC3B,CD46,RALB,RNASEH2A,PDE4D,EPHB4,SULT2B1,NAGA,MED30,ATG4D,FOXJ2,CYB5R2,DRAP1,PANK1,KIF1C,ATP1B1,RAD17,PKMYT1,ASB13,CBL,B3GALNT2,ITPR3,ATP10D,ZMPSTE24,AMZ2,DDOST,ACAD10,NGFRAP1,HAGHL,TRIOBP,SLC27A3,AREL1,CBX7,PRKAR1A,IGFBP6,DEPDC1,CBLL1,PBX3,HERC5,PLD2,FBXO6,DNAH3,FGF19,WWP2,SCML1,E2F7,RNF128,FUT8,CD9,ERBB3,CITED2,TTPA,MSH6,TGIF1,ALDH2,B3GNT2,LONRF3,PAPD7,ZC3H11A,TCFL5,ZKSCAN2,FBXO9,UBAC1,YES1,FOS,ARSK,KIF11,CPTP,CRTC2,CDK5RAP1,ACADSB,FGFR2,TBX18,ABCB1,RYK,ERAP1,LRRK1,ESPL1,MELK,CCNC,UGT8,FAF2,CRYM,UBE2Q1,VARS2,COMMD5,MAP1LC3B,ECI1,TRIM68,ADPRHL1,HSF2,METTL7A,CDKL5,TRPC1,ASH2L,IL1RAP,STK35,SP5,CERS2,CYP1B1,CXXC5,LAP3,ASXL1,ITCH,ACBD3,USP18,TYSND1,MAN2A2,HPSE,CAB39,ZNF165,SP6,GLA,CHPT1,CAPN1,NR2C2,PCSK5,PPP1R2,ZNF395,PPP1R12A,PYROXD2,ETV5,ASB9,ABCG2,CALM3,TEC,ADAMTSL4,DUSP5,QSOX2,TYW3,B3GALNT1,NOXA1,CES2,FAM20C,PFKL,OCRL,COL6A1,PRKCI,SRP54,BRAT1,NPTN,ZRANB1,GAD1,ETV7,CCDC88A,MDFI,ELK3,PDE5A,NUBP1,PDIK1L,STEAP1,SOX13,INSR,UAP1,RAB31,DCUN1D1,CTSA,JAK3,APOL2,COL16A1,RARG,DRD1,LMO7,CCNE2,DYNLRB1,PAX6,HDAC11,SOD2,PDIA5,COL18A1,OSR2,PHLDA1,EXT2,MXD1,SAP130,ZNF687,CYP4F11,KIF14,FABP6,ZBTB49,ECE1,NFKB2,ETHE1,UPF3A,CHP1,SEPHS1,SOAT1,RFK,PTPRU,MRPS35,GLO1,CDC25C,FANCE,CASP4,PDHX,ARHGAP35,SOCS3,HSF4,JADE1,ALDH5A1,STAT6,TLE1,PTBP3,SPTBN5,ABCA1,KDELC2,GLIS3,GCLM,ENO2,TSPAN15,SHPRH,CIT,TGFBR1,COL4A5,INTS8,TRIB2,NTAN1,SBF1,HDAC9,KIF5B,TOP2A,CARD8,ADRBK1,TAF1B,A4GALT,TOX2,RRBP1,ZDHHC13,KANK2,SLC35A1,RBMS2,MYO5A,B3GALT6,PGM1,DCAF6,WNT10B,CFAP46,RC3H2,RGCC,NADK2,RUNX3,TCEAL8,FOXL1,LEPR,ENDOD1,CTSL,CASP7,SWAP70,TRIM69,CTSV,CSGALNACT1,DTX4,ARRB1,ZMIZ1,CEP41,PLOD3,AHR,ABCG1,ACACB,KLK10,TRIM24,ADD1,MRPS15,AASS,TRIM5,DNAJC3,SMARCAL1,MMADHC,FBXO2,XIAP,CACNA2D2,DHX8,NRG2,LGI3,IL18,MORF4L2,CA8,BARD1,PHF1,TP73,CALM2,DAPK2,WEE1,PSMD1,TGFBR3,RGS12,DNAH6,CYP2S1,ALDH1A3,SLC46A1,KLF3,RDH14,FUT1,TUBG1,ACOX2,PIK3CD,TINAGL1,APOBEC3G,ERAP2,TUBA4A,SMARCA2,TNIP1,SPRTN,RNF11,MTRF1L,LOXL2,F12,ICMT,MYOM1,CYP4F3,COL12A1,SLC44A3,DNM1L,LIMK1,MYLK,MAP3K11,MRPS28,E2F8,PDPR,GAB1,HOXC13,ALDH6A1,NUAK1,CYP2J2,SOX9,ZNRF3,MERTK,LMNA,ELF3,RAVER2,GNS,DNPEP,FAM13B,NEK2,STT3B,NCAM1,NDUFA12,EPHX1,NAGPA,UFD1L,KIF20A,SALL4,STAT4,MYBL2,CALCRL,SRSF5,ILK,MEST,TP53INP2,SPTLC2,DCP2,CYB5A,DHX32,STK17A,PTPRF,NCOA3,NAAA,MTFMT,TIMM8A,HTT,SETD3,TEX30,ITPR1,AURKA,MDH1,ALG2,B4GAT1,ZNF502,RPS6KA3,XDH,EGLN1,MTM1,GRHL2,PAPSS2,TUBB4B,GALNT12,ACTR8,ETNK1,WDTC1,TESK2,PRSS22,PRKACA,CDS1,CCND1,RNF220,SP100,ACSL4,RAB27B,CDKN2D,RNF169,ENPP4,SSH3,NRBF2,PXYLP1,IRS2,WWTR1,INPP4B,TRABD2A,PDXK,GEN1,ARNT,GALK1,TNRC6C,TAOK2,NKX3-1,PARP14,MAN1A2,PDIA3,PKN1,ETS1,GSTP1,TSPAN17,HOXB2,PDIA4,DTX3L,CAPN2,SLC27A6,IRAK1,CTSC,ARSG,ALG13,FDXR,ECI2,ADAM15,WWP1,ZNF230,MAPK11,AK3,TMX1,CRTAP,POU6F1,NUDT8,FMN1,RAPGEF2,ELOVL3,EIF5A2,GRIN1,DBR1,BLVRA,NEURL1B,FAM109A,ABLIM2,TXK,GALNT3,PITX2,DCAF10,BTG1,ACVRL1,NR1D2,ATXN7L3,ZFP30,HMGA1,CENPE,NUP37,USF2,CYBRD1,FOXA1,UNKL,TRIM2,AGRN,GNPDA1,PPM1J,CUL4B,EPHA4,SUDS3,MCCC1,CDIPT,HDAC6,PDGFB,SDC1,PIGL,PCNA,SHC3,MKRN3,DDHD2,ELF5,DUSP10,TRAM1,MYBL1,DDX59,ZNF462,PCGF5,CD55,CITED4,C12orf65,EZR,ERP44,KLK6,PRKRA,IDH1,ZBTB7B,CDK1,VCP,RHEB,DPYSL3,IRX3,PLCH1,MSL1,WIPI1,P4HA2,DOLPP1,CTNND1,PIK3C2B,TTC9,POMT1,MAFF,PRKAA2,UBASH3B,ASAH1,B4GALT4,DHRS3,PGAP1,BMP2,RB1,IGF1R,GATA2,CMTR2,PAK2,EXOC8,MDFIC,PLCB2,ALDH3A2,PSMA5,ABCC1,CYP26B1,CHSY3,MRPS33,TESK1,PCBP3,KBTBD8,TCF7,EIF2AK1,ZDHHC3,G2E3,SMN1,MAPKAPK2,DHDH,H1F0,PRPS2,CTBP1,RNF146,UGP2,UPF3B,FOXM1,P3H2,XYLT1,DGKA,ZNF28,ERBB2,RASGRP3,SLC7A2,CCNL1,LPIN3,KBTBD11,CYP26A1,PER2,CDK14,RAD23A,LHX6,PLCG2,SRR,GYS1,MINPP1,EGLN3,FAR1,GM2A,DVL2,CTH,CPD,SIRT1,TCEB2,FIGNL1,CDC20,MYPOP,DNAJC10,DUOX1,ATP1A1,PTK7,PSMD3,ADAMTS14,ZBTB6,C1orf43,RPL22,LTA4H,AIFM3,CNEP1R1,NDST3,POMGNT2,ZNF701,ZC3HC1,MAN2B2,COL9A3,TRAPPC10,MACC1,DAP,BLVRB,GNE,SWI5,PSMD10,NKRF,JAG2,CHAC2,CRABP2,DSE,PPP2R3A,GBX2,BUB1,ABCD1,KLF9,HEXIM2,CAMK2G,FAH,HMMR,MLEC,PSMB4,NR3C1,AMFR,LITAF,PPARA,CAPNS1,PELI3,MAPK8IP1,SCRN2,PRDX4,FUCA1,SERPINA1,ZNF214,NAT1,CDCA7L,NMI,ACADM,SPCS3,NDFIP1,UBE2C,SAT2,DIS3L,GAA,ACVR1,ATP8A1,KLC2,TAP1,GATA3,CCNB1,PLA2G16,SLC20A1,CHST2,CTGF,ZFP36,IL31RA,STEAP2,AOX1,TFG,SMYD5,LOC81691,TMEM68,KIFC2,PBK,CASP9,MGAM,AGO4,PIF1,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SLC25A5,TP53I3,ULK2,SGPP1,AHRR,KDSR,HLF,SLC25A4,AREG,PLK2,GNPTAB,TBX1,PTER,DHTKD1,EIF4EBP2,TRAF5,LZTS1,DLAT,DDX58,KLF2,MRPL44,INPPL1,CDK17,DGKQ,ADO,SLC25A27,KIF23,NDUFA4,ISYNA1,SLC1A3,NOTCH2,KIAA1161,BMP2K,MECOM,CYR61,NECAB3,BDH1,CTPS1,OPN3,SORL1,PIKFYVE,CTSD,TSPAN33,EEF1D,TMED2,DNAI1,FADS2,QSOX1,B3GNT7,PMPCB,DDB2,MMD,ZNF84,PTPRH,PIP4K2C,PKM,CYFIP2,KDM3A,FBXO10,GLT8D2,RASA1,FAS,DGKH,SERTAD2,PRKAG2,DCK,CSNK1G1,NAB2,TCEAL4,NR4A2,MAP3K5,NRBP1,IRF1,PLA2G4A,ELK4,SLC2A4,RPS6KA1,IQGAP1,SUZ12,RNF182,EGR3,AIFM2,NUDT12,GNB2,TMPRSS4,APLP2,ZNF75D,DOK4,FICD,CDKN1B,DAB2IP,LGMN,PHKA2,NR2C1,GPX4,MYO5B,SEC23A,CAPN6,TEP1,SLC11A2,PRKCQ,AKR1E2,SP4,ZNF469,PRDM11,EPHA10,ZNF641,FYN,JAK1,ACYP1,STK26,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,RAB29,ZC3H12B,MLKL,HS3ST3B1,B4GALT3,NR3C2,ATMIN,MRPS9,OTUD5,NUDT6,PCOLCE,ATP9A,CDCA3,CYB561,APOBEC3H,SEPP1,SPR,PNPLA5,TEAD3,SIX4,FAM111A,OXCT1,PTEN,PPP1R10,MGAT1,SGK3,ATP8B1,SLC44A2,ERCC2,MAP3K7,CNOT6L,GFI1,TRIM62,OSGIN1,NCOA2,RASGRF1,PCCB,SHMT1,CASK,MPP1,TEF,PARP4,FURIN,C1GALT1C1,GPLD1,CTNS,PRDX3,CSTF2,PGM2L1,GRIN2D,ARSB,SLC25A38,CPEB2,OCLN,USP16,JARID2,CASP3,NMRK1,CPT2,ABHD17B,CAMKK1,EPHX4,UBE2Z,KIF2C,TAF6L,CACNB4,DNER,TSEN34,ABCD4,CHPF,MAGOHB,GRHL1,ZCCHC12,IMPAD1,DPYSL2,PHTF1,DLG1,AKR1B1,KIF22,NFU1,MYH14,ARNT2,TECR,PTPRE,RASGRP1,ATL1,TDP1,SOD1,TRIM8,ASCL5,RNF165,MRPS18A,ROR1,MRPS36,STK17B,ADRBK2,TCN2,SEC14L2,NEIL1,ZNF114,FASTKD1,DHRS13,UEVLD,IARS2,ADIPOR1,PSMC1,PPP2R5D,CPPED1,FAM213B,ELOVL7,ASL,PHLPP1,ZNF432,OTUD1,CA2,EBF4,ZNF692,RFX5,ACAD8,NCEH1,LRIF1,DESI2,OXR1,GYLTL1B,HMG20B,FBXO8,AMDHD1,EGFR,GLCE,GNAS,FECH,NUDT16,ONECUT1,TSC1,SLC6A6,PLPP3,UTP14C,PAPD5,CDCA5,ALPK3,PITPNA,YOD1,KIF12,KLF7,FBXW5,IL15,SLC2A8,PSME2,ABCG4,GMPR,TDRKH,PATL2,SS18,SETDB2,FRYL,ZDHHC12,TWIST1,STEAP3,RPN2,GOT1,APIP,PDIA6,LOXL1,F2R,SCYL3,FRS3,MAP3K3,GCA,ZNF525,TAF5,DUSP4,SNAPC2,MAP3K6,PEX2,OVOL1,CANT1,CYP2U1,AKNA,CBX4,CDS2,JKAMP,MIER3,AES,NOTUM,TRMT2B,POMGNT1,ZNF212,ADORA1,GALNS,TRIM3,BRD7,MXD3,IQGAP3,ADAM17,RAB3B,GCLC,NR4A1,MBNL3,OGDHL,POLD3,SPAG1,KLHL2,MARC1,DHRS2,PRCP,HNRNPH2,TADA2B,UBE2D2,OTUB2,GLB1,HOXB13,SOX8,ZNF596 |
| 2.620e-02 | -3.64 | GNF2_SPTA1 | MSigDB lists | GNF2_SPTA1 | 77 | 18 | 17758 | 2588 |
TMCC2,ERMAP,GCLC,MPP1,BLVRB,BNIP3L,FBXO9,EIF2AK1,SPTB,RAD23A,FECH,MARCH8,ANK1,CA2,H1F0,FBXO7,MINPP1,TRAK2 |
| 2.620e-02 | -3.64 | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN | MSigDB lists | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN | 77 | 18 | 17758 | 2588 |
LMO7,CPEB4,CYB5R2,MRS2,FAM46C,FLT3,ICAM1,SYTL2,SOCS3,RASSF8,NOV,TYW3,CA2,FAM46A,LRIF1,PTGES,ESPL1,IFI6 |
| 2.626e-02 | -3.64 | calcium activated phosphatidylcholine scrambling | biological process | GO:0061590 | 5 | 3 | 16441 | 2455 |
ANO9,ANO4,ANO6 |
| 2.626e-02 | -3.64 | mitotic centrosome separation | biological process | GO:0007100 | 5 | 3 | 16441 | 2455 |
AURKA,NDE1,KIF11 |
| 2.626e-02 | -3.64 | aortic valve morphogenesis | biological process | GO:0003180 | 5 | 3 | 16441 | 2455 |
GATA3,TWIST1,EFNA1 |
| 2.626e-02 | -3.64 | apolipoprotein A-I-mediated signaling pathway | biological process | GO:0038027 | 5 | 3 | 16441 | 2455 |
ITGAV,RHOA,ABCA1 |
| 2.626e-02 | -3.64 | nucleotide-binding oligomerization domain containing 2 signaling pathway | biological process | GO:0070431 | 5 | 3 | 16441 | 2455 |
RIPK2,NFKBIA,NOD2 |
| 2.626e-02 | -3.64 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification | biological process | GO:0015015 | 5 | 3 | 16441 | 2455 |
HS6ST1,HS3ST3B1,HS6ST3 |
| 2.626e-02 | -3.64 | cellular lipid biosynthetic process | biological process | GO:0097384 | 5 | 3 | 16441 | 2455 |
FAR2,FAR1,AGPS |
| 2.626e-02 | -3.64 | ether lipid biosynthetic process | biological process | GO:0008611 | 5 | 3 | 16441 | 2455 |
FAR2,FAR1,AGPS |
| 2.626e-02 | -3.64 | leucine catabolic process | biological process | GO:0006552 | 5 | 3 | 16441 | 2455 |
HMGCL,MCCC2,MCCC1 |
| 2.626e-02 | -3.64 | positive regulation of cyclic-nucleotide phosphodiesterase activity | biological process | GO:0051343 | 5 | 3 | 16441 | 2455 |
CALM3,CALM2,CALM1 |
| 2.626e-02 | -3.64 | regulation of rubidium ion transport | biological process | GO:2000680 | 5 | 3 | 16441 | 2455 |
CAB39,STK39,CD63 |
| 2.626e-02 | -3.64 | common myeloid progenitor cell proliferation | biological process | GO:0035726 | 5 | 3 | 16441 | 2455 |
GSTP1,FLT3,NR4A3 |
| 2.626e-02 | -3.64 | response to corticotropin-releasing hormone | biological process | GO:0043435 | 5 | 3 | 16441 | 2455 |
NR4A2,NR4A1,NR4A3 |
| 2.626e-02 | -3.64 | regulation of mast cell cytokine production | biological process | GO:0032763 | 5 | 3 | 16441 | 2455 |
BCL6,BCL10,NR4A3 |
| 2.626e-02 | -3.64 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | biological process | GO:1901621 | 5 | 3 | 16441 | 2455 |
PRKACA,TRAF3IP1,GPR161 |
| 2.626e-02 | -3.64 | calcium activated galactosylceramide scrambling | biological process | GO:0061591 | 5 | 3 | 16441 | 2455 |
ANO9,ANO4,ANO6 |
| 2.626e-02 | -3.64 | cellular response to corticotropin-releasing hormone stimulus | biological process | GO:0071376 | 5 | 3 | 16441 | 2455 |
NR4A2,NR4A1,NR4A3 |
| 2.626e-02 | -3.64 | bone mineralization involved in bone maturation | biological process | GO:0035630 | 5 | 3 | 16441 | 2455 |
BMP2,PHOSPHO1,ANO6 |
| 2.626e-02 | -3.64 | glycerol ether biosynthetic process | biological process | GO:0046504 | 5 | 3 | 16441 | 2455 |
FAR2,FAR1,AGPS |
| 2.626e-02 | -3.64 | ferric iron import | biological process | GO:0033216 | 5 | 3 | 16441 | 2455 |
STEAP3,STEAP1,STEAP2 |
| 2.626e-02 | -3.64 | aortic valve development | biological process | GO:0003176 | 5 | 3 | 16441 | 2455 |
GATA3,TWIST1,EFNA1 |
| 2.626e-02 | -3.64 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway | biological process | GO:0002484 | 5 | 3 | 16441 | 2455 |
HLA-B,HLA-C,HLA-A |
| 2.626e-02 | -3.64 | polyamine catabolic process | biological process | GO:0006598 | 5 | 3 | 16441 | 2455 |
DHPS,SAT2,SAT1 |
| 2.626e-02 | -3.64 | dichotomous subdivision of terminal units involved in salivary gland branching | biological process | GO:0060666 | 5 | 3 | 16441 | 2455 |
PLXND1,PLXNA1,SEMA3A |
| 2.626e-02 | -3.64 | STAT protein import into nucleus | biological process | GO:0007262 | 5 | 3 | 16441 | 2455 |
HES1,JAK3,F2R |
| 2.626e-02 | -3.64 | ether biosynthetic process | biological process | GO:1901503 | 5 | 3 | 16441 | 2455 |
FAR2,FAR1,AGPS |
| 2.626e-02 | -3.64 | negative regulation of cell volume | biological process | GO:0045794 | 5 | 3 | 16441 | 2455 |
P2RX7,CLCN3,ANO6 |
| 2.626e-02 | -3.64 | mesangial cell development | biological process | GO:0072143 | 5 | 3 | 16441 | 2455 |
ACTA2,OSR1,PDGFB |
| 2.626e-02 | -3.64 | negative regulation of cyclic-nucleotide phosphodiesterase activity | biological process | GO:0051344 | 5 | 3 | 16441 | 2455 |
MAPK7,AIP,EGLN1 |
| 2.626e-02 | -3.64 | ferric iron import into cell | biological process | GO:0097461 | 5 | 3 | 16441 | 2455 |
STEAP3,STEAP1,STEAP2 |
| 2.626e-02 | -3.64 | fungiform papilla morphogenesis | biological process | GO:0061197 | 5 | 3 | 16441 | 2455 |
HDAC1,CTNNB1,SIX4 |
| 2.626e-02 | -3.64 | calcium activated phospholipid scrambling | biological process | GO:0061588 | 5 | 3 | 16441 | 2455 |
ANO9,ANO4,ANO6 |
| 2.626e-02 | -3.64 | spindle stabilization | biological process | GO:0043146 | 5 | 3 | 16441 | 2455 |
AURKA,AURKB,CCNB1 |
| 2.626e-02 | -3.64 | regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | biological process | GO:0031585 | 5 | 3 | 16441 | 2455 |
PKD2,HTT,MYO5A |
| 2.626e-02 | -3.64 | chorionic trophoblast cell differentiation | biological process | GO:0060718 | 5 | 3 | 16441 | 2455 |
E2F7,FZD5,E2F8 |
| 2.626e-02 | -3.64 | ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2) | protein interactions | 10425 | 66 | 17 | 16036 | 2547 |
SGCE,PAPSS2,TCEB2,UGP2,ASB9,TP53,NUBP1,RHEB,VCP,UBE2T,PHF7,UBE2D2,ARAP1,BUB1,WDR91,GFI1,EHD1 |
| 2.626e-02 | -3.64 | PRG2 (proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)) | protein interactions | 5553 | 66 | 17 | 16036 | 2547 |
GID8,RMND5A,ADAMTS2,COL6A2,AKT1,PHLDB3,RANBP9,HLA-A,SIPA1L2,ZMYND19,TUBGCP6,PASK,ACTA2,PPP6R1,MELK,DVL2,TUBA4A |
| 2.626e-02 | -3.64 | OPTN (optineurin) | protein interactions | 10133 | 66 | 17 | 16036 | 2547 |
SOD1,TNIP1,MPP1,CALM1,EIF5A2,RNF11,GTF3A,MAP1LC3B,FOS,OPTN,GABARAPL1,GNAS,FLII,TBC1D17,HTT,HSPB1,RAB3IL1 |
| 2.627e-02 | -3.64 | SHH_subtype | COSMIC cancer mutations | SHH_subtype | 679 | 117 | 17775 | 2585 |
MTM1,PPP4R4,GRHL2,LGR4,PAPSS2,ARFGEF1,TP53,P2RX7,VARS2,CAMK1D,ITPR2,SLC7A2,SNX9,TMC1,DENND2D,CYP39A1,ZNF385B,SLC9A7,SH3KBP1,GRM5,DAPK2,MUC16,CTNNB1,SP100,PAPSS1,ANKFN1,MITF,PIK3CA,DAB2IP,PDE4D,SCN2A,ZNF365,CPE,MCTP1,UTRN,CDCA2,PRKCQ,KIF13A,LDB2,TANC1,PPP1R14C,IDH1,ALCAM,DOCK5,EBF2,OSBPL2,TRAM2,STAT6,NOD2,MAOA,NRG1,GLA,GLCCI1,COBL,ARNT,FAM134B,PRKAR1A,DENND5B,DDX58,RUNX2,LRRFIP2,PARP14,TBC1D1,ATP9A,ITGA6,ABCG2,GABRG2,SELL,PBX3,SLC36A4,CNTNAP2,INTS8,DNAH3,ANO1,ZDHHC21,CD109,BMP2,CA2,ITGB8,PIK3AP1,ARSG,FAM189A1,CTSC,GPC3,MAP3K9,KIAA0319,PRKG1,CACNA1D,RPGR,MYO5A,CHSY3,RGMB,PARD3B,MRS2,SYBU,FBXO8,MAML2,ZSCAN12,KDM3A,ANTXR1,EGFR,BSDC1,PDE11A,TXK,KLHL2,FECH,PLEKHH2,PRKAG2,SYT7,TBX18,C1orf21,AMMECR1,ALPK3,GRAMD1C,ATP6V1C1,SEMA3A,DOCK9 |
| 2.629e-02 | -3.64 | CDKN1B (cyclin-dependent kinase inhibitor 1B (p27, Kip1)) | protein interactions | 1027 | 81 | 20 | 16036 | 2547 |
CCNE2,RHOA,AKT1,TRAF2,RPS6KA1,CUL1,UBAC1,YES1,CCNB1,CDK1,VCP,CCND1,TSC1,CCNA2,UBE2D2,CKS1B,SGK1,TRIM21,KPNA2,IRF1 |
| 2.630e-02 | -3.64 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological process | GO:0002824 | 70 | 17 | 16441 | 2455 |
RIPK2,HLA-E,TRAF2,P2RX7,WHSC1,IL27RA,PRKCQ,CD40,HLA-A,HLA-B,PVRL2,STAT6,NOD2,FZD5,MAP3K7,MSH6,SOCS5 |
| 2.631e-02 | -3.64 | MODULE_88 | MSigDB lists | MODULE_88 | 811 | 138 | 17758 | 2588 |
MYL9,BCAM,HSPG2,EPAS1,CRYM,NRG2,PLA2G16,SDC1,ECI1,EPCAM,ZYX,PHYHIP,ALDH1A3,DNM2,CLDN4,TACSTD2,ACOX2,CPE,SMAGP,SGCE,F12,CCNF,TCN2,MDK,ENPP1,GPRC5B,TBX1,MYLK,BMP1,NRGN,GRN,PRSS8,CYP2J2,DNAJB2,ITGA6,SOX9,DHRS3,TSPAN7,SPP1,RAC2,CA2,ITGA3,CYR61,LYPD3,GATA2,KCNN4,NECAB3,BDH1,TBCD,COL6A1,PLCB2,ALDH3A2,RIMS2,EPHX1,FADS2,TCF7,DPYSL4,RHOB,EGFR,CDK5R1,CYB5A,IL1R1,NAAA,SLC4A4,ETS2,PVRL2,ITGA7,RAB31,STK39,CDK18,EFNA1,JAK3,XDH,PAX6,NQO1,S100A11,THRA,PTTG1,GMPR,COL18A1,PHLDA1,IER3,CCND1,SCNN1A,CDH1,SRPX,TACC2,GOT1,IFIT1,LGMN,TSPAN1,HSPA2,CKS2,COL6A2,PFKFB2,S100A4,CDC20,MAOA,ABCA1,PCOLCE,IGFBP6,ATP9A,GNE,BLVRB,GDF15,SEPP1,DNAH3,HOXB2,ITGA2B,RND1,CTSC,GPC3,GALNS,TFAP2A,ALDH7A1,IGFBP2,ERBB3,CITED2,HCN3,SHMT1,WNT10B,NR4A1,FURIN,EMP3,AK4,COL7A1,FOS,PROM1,TIMP3,SERPINA1,FGFR2,DHRS2,DTX4,ARFGAP3,UBE2C,L1CAM,OCLN,CD33 |
| 2.632e-02 | -3.64 | DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER | MSigDB lists | DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER | 99 | 22 | 17758 | 2588 |
CMAS,BAG4,ING1,PPP1R12A,DBR1,CBLL1,TRIM35,GTF3A,FAM91A1,KBTBD11,RASA1,ANKRD10,NAPG,PAK2,RYK,PRKCI,PIK3CA,H2AFY,MRPS28,ASH2L,RAB20,CTTN |
| 2.632e-02 | -3.64 | MORF_CASP2 | MSigDB lists | MORF_CASP2 | 99 | 22 | 17758 | 2588 |
WNT10B,FAM189A2,PFKFB2,PCBP3,PTPN9,KIF1C,TCF7,PKMYT1,CARD10,SLC9A3R2,M6PR,HSF4,KHNYN,PPP1R10,MGAT1,PAIP2B,FDXR,MPP2,ANKRD12,ADAM15,B4GALT3,GPR161 |
| 2.632e-02 | -3.64 | MODULE_177 | MSigDB lists | MODULE_177 | 99 | 22 | 17758 | 2588 |
NR3C1,MPP1,CDC20,ARHGDIB,IFIT3,LBR,RHOB,LCP1,CD83,TOP2A,BTG1,JAK1,DDOST,NMI,PLCG2,NFKBIA,RANBP1,SORL1,SGK1,TRAM1,ST3GAL1,TMED2 |
| 2.634e-02 | -3.64 | negative regulation of multicellular organismal process | biological process | GO:0051241 | 967 | 166 | 16441 | 2455 |
SIGIRR,LGR4,TSC22D3,EPHA4,GATA3,NDRG2,VASH1,PDGFB,FAM101B,TP73,CTNNB1,DUSP10,TACSTD2,SEMA3G,SOD1,ACVR1C,ITCH,EZR,ARHGDIB,EAF2,F12,SAV1,ULK2,ABR,IRX3,DPYSL3,ENPP1,AREG,PLK2,HOXA9,TRAF3IP1,RAB11FIP1,NOD2,ARF6,F2RL1,DDX58,SEMA6B,KLF2,SERPINE2,UBASH3B,SOX9,FBLN1,BMP2,CALR,SPP1,TIMP1,GATA2,VASN,FBXO7,PRKG1,SORL1,C10orf54,NTN1,WNT3A,MYLIP,GPR161,SOCS5,PDE5A,CALCRL,NFIB,CDK5R1,GNAS,SEMA4D,NFKBIA,NLRC5,SFMBT1,STK39,EFNA1,GDF11,IFIH1,JAK3,SEMA3A,TOB1,RARG,XDH,DRD1,IRF1,GAS2L1,PAX6,GRHL2,LFNG,NLRX1,INPP5D,TP53,ERBB2,P2RX7,CD274,PRKACA,FLT3,PDGFA,SVBP,NOV,SP100,BCL6,SMO,CDKN1B,CDH3,DAB2IP,DIXDC1,TWIST1,PDE4D,NOTCH3,LGMN,ETV4,F2R,SEMA3B,DOCK4,PTGER4,DOCK5,FZD7,PTGS2,ATP1A1,AXL,CORO1C,INPP4B,STAT1,RAB29,NRG1,CTDSP1,OTUD5,NKX3-1,ADGRG1,CIT,LRP4,HERC5,TGFBR1,TRIB2,GSTP1,SIX4,ADGRB2,PDCD10,RNF128,ADRBK1,ADORA1,PTEN,BMP7,CST3,KIAA0319,MAPK11,ITM2C,GFI1,TRIM62,P2RX4,HES1,RHOA,ASPM,RAPGEF2,PLAUR,PIK3R1,RGCC,FURIN,PRICKLE1,BBS2,PRDX4,CD83,BANK1,ACVRL1,TWSG1,TBX18,NMI,ARRB1,OSR1,SOX8,NDFIP1,FOXA1,NGEF |
| 2.636e-02 | -3.64 | PROTEIN_AMINO_ACID_DEPHOSPHORYLATION | MSigDB lists | PROTEIN_AMINO_ACID_DEPHOSPHORYLATION | 61 | 15 | 17758 | 2588 |
PTPRJ,PTPN18,SSH1,PTEN,PTPN9,PTPRH,PPP2R4,DUSP10,PPP1CA,DUSP4,SBF1,PTPRE,DUSP5,PPP2R3A,EPM2A |
| 2.636e-02 | -3.64 | PROTEIN_KINASE_BINDING | MSigDB lists | PROTEIN_KINASE_BINDING | 61 | 15 | 17758 | 2588 |
TOP2A,CDKN2C,IRAK1,PRDX3,KIF13B,DLG1,NOD2,AKAP3,CDKN2D,BCAR1,MAPK8IP1,CCDC88A,PICK1,ZC3HC1,BCL10 |
| 2.637e-02 | -3.64 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG pathways | ko00532 | 20 | 7 | 6908 | 1076 |
B3GALT6,CHSY3,DSE,XYLT2,XYLT1,CSGALNACT1,CHPF |
| 2.637e-02 | -3.64 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG pathways | hsa00532 | 20 | 7 | 6908 | 1076 |
B3GALT6,CHSY3,DSE,XYLT2,XYLT1,CSGALNACT1,CHPF |
| 2.639e-02 | -3.63 | GSE25087_FETAL_VS_ADULT_TCONV_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TCONV_UP | 185 | 37 | 17758 | 2588 |
CTSB,TP53,PSME1,ITPR2,TMEM19,RCN1,PTEN,CTSC,LMO4,BAX,RFX5,NFKB2,FAR2,TIPARP,MCCC2,MSH6,ABCC1,NFE2L3,PDGFC,ORAI2,B3GNT2,CENPA,DENND1B,KCTD20,ATP1B1,AIF1L,SLC25A5,ADRBK2,AHRR,SLC6A6,NEIL3,PLEKHG1,STAT1,PIK3C2B,HMGA1,ZMIZ1,CCDC97 |
| 2.639e-02 | -3.63 | GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP | MSigDB lists | GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP | 185 | 37 | 17758 | 2588 |
ANXA3,LRRFIP2,NFKBIE,SCD5,MRAS,CTSZ,TEX2,KBTBD11,ARHGEF16,WWP2,IER3,BMP2,FAM46A,FLRT3,BCL6,ADCK2,TAX1BP3,SGK1,PIM1,EGLN3,ASPM,SAT1,CBX6,PYGL,MGAM,NPC2,IFIT3,DOCK5,SPTLC2,CD83,TBC1D17,SERPINA1,NFKBIA,RAP2C,MAFF,CPPED1,IRF1 |
| 2.639e-02 | -3.63 | GSE3982_EOSINOPHIL_VS_NKCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_NKCELL_UP | 185 | 37 | 17758 | 2588 |
MTM1,REPS2,LGR4,BIK,ASAH1,FTH1,NOTCH2,CAMK1D,SNN,CMTM6,TEAD3,CYP1A1,LHX6,BCL6,SGK1,FAM102A,C2orf72,CKAP4,ORAI2,PRODH,NRBF2,PYGL,ERP44,SNTB1,HLA-B,SLC6A6,SWAP70,AREG,TBX1,TTC9,LSM14B,ZMIZ1,MAD2L1BP,RTN3,AHR,EGLN1,RRAGD |
| 2.641e-02 | -3.63 | UBXN7 (UBX domain protein 7) | protein interactions | 26043 | 76 | 19 | 16036 | 2547 |
SEC23A,UFD1L,LZTFL1,TCEB2,KLHL13,AMFR,CUL4B,CUL1,DPP8,PJA2,VPS26A,VCP,ZYX,WDR11,OXCT1,ALPP,KBTBD2,UBE2D2,UBE2C |
| 2.648e-02 | -3.63 | CCAGGGG,MIR-331 | MSigDB lists | CCAGGGG,MIR-331 | 88 | 20 | 17758 | 2588 |
TAOK2,LGALS3,ASXL1,FURIN,WHSC1,OSR2,FXR2,EGR3,PHLPP1,DAG1,GNB2,NRP2,VCP,KCTD15,KHNYN,SYT7,TSPAN18,SPRY4,RARG,TBC1D10B |
| 2.648e-02 | -3.63 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | MSigDB lists | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | 88 | 20 | 17758 | 2588 |
SEC23A,KIF3C,KIF20A,CTSB,KLC2,KIF23,RACGAP1,KIF2C,KIF26A,KIF11,DCTN6,KIF5B,AP1M2,CTSC,DNM2,KLC3,KIF22,CTSA,LGMN,CTSD |
| 2.648e-02 | -3.63 | KANG_IMMORTALIZED_BY_TERT_UP | MSigDB lists | KANG_IMMORTALIZED_BY_TERT_UP | 88 | 20 | 17758 | 2588 |
PDGFC,COL6A2,CENPA,MAPK4,CTSZ,COL7A1,BCL2L1,PDGFB,LEPR,APPBP2,RHEB,ICAM1,SLC6A6,ITGA3,TJP3,CABP1,P4HA2,TFAP2A,CKS1B,CLMN |
| 2.665e-02 | -3.63 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_UP | 191 | 38 | 17758 | 2588 |
CMAS,ARHGEF3,NQO1,CD82,GATA3,C1orf198,MAPK4,TP53I11,LACTB2,KTN1,BCAP31,UHRF1BP1L,TFAP4,MTMR10,TNFRSF18,TAGLN2,FAM84B,PDE4D,CITED2,DGKG,PTPN18,ASXL1,STAU2,CALCRL,LDB2,TMTC2,BSDC1,STX3,SOCS3,NUCB1,DNAJC10,AGPAT2,ACYP1,RAP2C,VSIG10,PLXND1,CD81,NDFIP1 |
| 2.665e-02 | -3.63 | GSE17721_PAM3CSK4_VS_CPG_4H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_4H_BMDM_DN | 191 | 38 | 17758 | 2588 |
LMO7,KLF2,TCTN2,PSME2,HLA-E,DGKA,CD274,ARHGEF40,ETS1,TNFSF9,MXD1,CDK14,ELF5,IRF2,ALDH7A1,PIM1,TFG,TIAM1,ATG4D,ENPP4,GCA,B3GNT2,NUB1,CCBL2,VWA1,KIAA1109,RAB3IP,CD40,SPTLC2,ARF4,PTGS2,PLEKHG6,ANKRD6,NAT1,ITPR1,STK39,ST3GAL1,IRF1 |
| 2.665e-02 | -3.63 | GSE27786_NKTCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_NKTCELL_VS_ERYTHROBLAST_UP | 191 | 38 | 17758 | 2588 |
BIN1,AVPI1,TCF25,FBXO6,IFT27,EXT2,IRF2BPL,ZFP36,GALNS,FDXR,SLC30A6,CAPG,BCL6,ECE1,OSBPL7,GM2A,P2RX4,MAP3K3,PLSCR1,PSMB4,OSTM1,SNTB2,CAPNS1,ICMT,PSMA4,NMT2,DDOST,ABHD12,ACYP1,TRIM45,CANT1,GLB1,VSIG10,STK39,ZMIZ1,LSM14B,TMEM120A,CPEB2 |
| 2.665e-02 | -3.63 | GSE27786_CD8_TCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NKTCELL_DN | 191 | 38 | 17758 | 2588 |
UNC93B1,CDS2,ARAP3,PPM1J,SLC2A8,RASA2,CD82,TEX2,TMEM170B,NUDT12,FZD6,DOPEY2,PPP4R1,RUNDC3B,UBE2J1,SORL1,H2AFY,TNFRSF18,WWP1,TECR,GFI1,MX1,LAMP2,PLSCR1,KDM4D,GABARAPL1,FRMD4B,GNAS,CARHSP1,NAAA,AGPAT2,TDRD7,RELL1,HMGA1,GEM,ARPC2,LIFR,TMEM173 |
| 2.665e-02 | -3.63 | GSE2826_WT_VS_XID_BCELL_DN | MSigDB lists | GSE2826_WT_VS_XID_BCELL_DN | 191 | 38 | 17758 | 2588 |
TM2D2,IGFBP6,EPAS1,HEBP1,TRAF2,XIAP,ABCG2,VPS26A,MESDC2,SNTA1,PDGFA,SPP1,BRD7,ECE1,TMEM37,NFKB2,CDKN2D,SLC12A2,CPD,LAMP2,DSTN,GLO1,ATP1B1,F12,DOCK5,MAP3K6,GLCE,GALNT3,MAPKAPK2,AXL,P4HA2,CDK18,CHMP4B,CTSA,SERPINB6,UBE2C,CBX7,PTGES |
| 2.665e-02 | -3.63 | GSE11924_TFH_VS_TH1_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH1_CD4_TCELL_UP | 191 | 38 | 17758 | 2588 |
ANXA3,PINK1,AGRN,MACC1,TBC1D1,IQGAP1,CAST,WDTC1,CYHR1,APLP2,CEP97,ACAP2,SETDB2,IGF1R,NPNT,KIF13B,OSBPL3,CCDC82,ERBB3,LGMN,TMEM8A,CPE,ATP2B1,SUN2,ORAI2,FAM160A1,RC3H2,MEST,IFIT3,NDRG3,CASP4,ATXN7L3,ARAP1,ICOSLG,BTBD6,ARNT,CBX4,CCDC97 |
| 2.665e-02 | -3.63 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP | 191 | 38 | 17758 | 2588 |
HSP90B1,GALNT12,INPP5D,PRKAA1,PDIA3,PKN1,FAM46C,DUSP5,BCAP31,PDIA4,NAPG,DPYSL2,PAK2,DUSP10,AHCY,OSTF1,NPTN,TRAM1,KCTD3,TMED2,SMARCA2,ORAI2,AGPS,SNTB2,PIK3R1,RNF11,SYNE2,EZR,DNAJB14,STK17B,HNRNPH2,CORO1C,PPP1CB,SPCS3,TOB1,RTN3,ATMIN,SRSF9 |
| 2.665e-02 | -3.63 | GSE17721_LPS_VS_POLYIC_24H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_24H_BMDM_DN | 191 | 38 | 17758 | 2588 |
TMEM184B,ZNF395,PSME2,IQGAP1,PTTG1,ARL4C,SUDS3,ERCC6L,KCTD12,PSME1,PLA2G16,SLC25A45,SLC16A6,FAM13B,CAPG,MTMR10,IRF2,ARNT2,PLCB2,CTDSP2,SIRT1,LAMP2,GCA,FZD4,IFITM3,SHARPIN,CBX6,EMP3,FNDC3A,GIGYF1,RND3,DOLPP1,RAP2C,SPINT2,ARRB1,PRIMA1,L1CAM,JARID2 |
| 2.670e-02 | -3.62 | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN | 156 | 32 | 17758 | 2588 |
COL9A3,SORT1,ETV5,SOD2,COL4A5,FTH1,MXD1,SIRPA,CORO1B,WWP2,BTG3,TSPAN6,REEP1,RAB20,HSPA13,TAGLN2,PDE4D,CACNA1D,RIPK2,MFI2,PLAUR,BNIP3L,DIAPH2,ZFAND5,STK17B,H1F0,HOXA9,FGF18,MPP2,DYSF,SERPINB1,ARNT |
| 2.673e-02 | -3.62 | positive regulation of leukocyte activation | biological process | GO:0002696 | 274 | 53 | 16441 | 2455 |
LAMP1,DHPS,IL15,INPP5D,HLA-E,TRAF2,GATA3,IL18,EGR3,CD274,TNFSF9,EFNB1,HLA-A,CD46,IL6ST,PAK2,BCL6,PIK3CA,IGFBP2,MAP3K7,RAG1,SLC39A10,WNT3A,FLOT2,SYK,RASGRP1,MSH6,SOCS5,HES1,CD55,RHOA,RIPK2,AKT1,LGALS8,PIK3R1,WHSC1,PRKCQ,YES1,CD40,BCL10,CD83,IRS2,FYN,PVRL2,STAT6,AXL,NOD2,NR4A3,PPP2R3C,ICOSLG,CD81,JAK3,F2RL1 |
| 2.675e-02 | -3.62 | Folic Acid Network | WikiPathways | WP1311 | 2 | 2 | 4455 | 729 |
TXN,FMN1 |
| 2.675e-02 | -3.62 | Folic Acid Network | WikiPathways | WP1273 | 2 | 2 | 4455 | 729 |
TXN,FMN1 |
| 2.675e-02 | -3.62 | Folic Acid Network | WikiPathways | WP1075 | 2 | 2 | 4455 | 729 |
TXN,FMN1 |
| 2.675e-02 | -3.62 | PDGF Pathway | WikiPathways | WP2526 | 2 | 2 | 4455 | 729 |
PDGFA,PDGFB |
| 2.675e-02 | -3.62 | ARFGAP1 (ADP-ribosylation factor GTPase activating protein 1) | protein interactions | 55738 | 42 | 12 | 16036 | 2547 |
GRN,LASP1,RAB23,AURKA,ARFGAP3,RPL22,DLG3,MAP1LC3B,FOS,SMN1,TMED2,KDELR1 |
| 2.675e-02 | -3.62 | EPHB2 (EPH receptor B2) | protein interactions | 2048 | 42 | 12 | 16036 | 2547 |
HMMR,PLCG1,STK26,SH2D3C,GRIN1,RYK,EFNA5,YES1,FOS,EFNB1,PICK1,RASA1 |
| 2.685e-02 | -3.62 | Trafficking of myristoylated proteins to the cilium | REACTOME pathways | R-HSA-5624138 | 5 | 3 | 8202 | 1235 |
RP2,NPHP3,CYS1 |
| 2.685e-02 | -3.62 | APOBEC3G mediated resistance to HIV-1 infection | REACTOME pathways | R-HSA-180689 | 5 | 3 | 8202 | 1235 |
HMGA1,PSIP1,APOBEC3G |
| 2.685e-02 | -3.62 | Activation of caspases through apoptosome-mediated cleavage | REACTOME pathways | R-HSA-111459 | 5 | 3 | 8202 | 1235 |
CASP3,CASP7,CASP9 |
| 2.685e-02 | -3.62 | Cytochrome c-mediated apoptotic response | REACTOME pathways | R-HSA-111461 | 5 | 3 | 8202 | 1235 |
CASP3,CASP7,CASP9 |
| 2.685e-02 | -3.62 | Cyclin B2 mediated events | REACTOME pathways | R-HSA-157881 | 5 | 3 | 8202 | 1235 |
CDC25C,CCNB2,CDK1 |
| 2.685e-02 | -3.62 | CaMK IV-mediated phosphorylation of CREB | REACTOME pathways | R-HSA-111932 | 5 | 3 | 8202 | 1235 |
CALM2,CALM3,CALM1 |
| 2.685e-02 | -3.62 | vesicle localization | biological process | GO:0051648 | 233 | 46 | 16441 | 2455 |
DOC2A,GRN,TRAPPC10,P2RX7,CTSZ,PLD2,SYTL4,SYTL2,KIF5B,AP1M2,CTNNB1,CTSC,DPYSL2,DNM2,CPLX1,LMAN1,TFG,RAB27B,PACSIN1,SYTL3,PPP6R1,TMED2,MYO5A,RASGRP1,SEC23A,RAB3B,SCRIB,KIF13A,COL7A1,MCFD2,BBS2,STX3,TRIM9,AP1AR,SERPINA1,FGFR2,SYT7,AREG,HTT,WIPI1,SYT13,NDE1,SHROOM2,TC2N,COPG1,SNPH |
| 2.686e-02 | -3.62 | NCOR2 (nuclear receptor corepressor 2) | protein interactions | 9612 | 112 | 26 | 16036 | 2547 |
THRB,SIRT1,NFKBIE,AKT1,NR3C1,NR4A1,THRA,PPARA,MYBL2,CBX6,FOS,RANBP9,CNOT2,NCOA3,NFKBIA,E2F1,BCL6,AURKA,HDAC1,KLF5,NR4A2,HMGA1,AHR,RARG,ARNT,CTBP1 |
| 2.686e-02 | -3.62 | BCL2 (B-cell CLL/lymphoma 2) | protein interactions | 596 | 112 | 26 | 16036 | 2547 |
CASP3,BAG4,SOD1,BMF,NR4A1,BIK,TP53,BNIP3L,BCL2L1,PKMYT1,PRKACA,CDK1,BCAP31,SMN1,NMT2,RHEB,CAPN2,IRS2,PPP2R5A,ITPR1,PPP2R4,BAX,PPP1CB,TMBIM6,MAPK11,PPP1CA |
| 2.687e-02 | -3.62 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDM_DN | 197 | 39 | 17758 | 2588 |
AGRN,PARP14,CKAP2,PSME2,SLC41A1,SERPINB9,DGKA,PDCL,PSME1,CD274,ARHGEF40,SPSB1,KTN1,CMTM6,CDK14,MAGOHB,GALNS,FUT1,TNPO2,SGK1,IRF2,RAB20,ACOX2,TIPARP,NR2C1,C9orf72,PARP9,STAT4,NUB1,ATP8B3,POLD3,TAPBP,SLC6A6,TIMP3,C19orf66,WFS1,GNPTAB,CHMP4B,PTGES |
| 2.687e-02 | -3.62 | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | 197 | 39 | 17758 | 2588 |
CCNE2,CASP3,NUDT6,NF2,EPAS1,BLVRB,NDC80,ETNK1,PDIA5,CMTM6,NAPG,ATP6V0B,SIVA1,PSMC2,KNTC1,MANF,SGCB,HSPA2,ALDH3A2,DDB2,ITCH,MPP1,FHL2,GLO1,BLVRA,ICMT,SLC25A5,IDH1,FANCE,GINS4,CASP7,CTNS,DNM1L,P4HA2,NEIL3,HMGA1,CENPE,ATP6V1C1,MELK |
| 2.688e-02 | -3.62 | BRO1 | pfam domains | PF03097 | 5 | 3 | 16629 | 2504 |
RHPN2,BROX,RHPN1 |
| 2.688e-02 | -3.62 | TPR_7 | pfam domains | PF13176 | 5 | 3 | 16629 | 2504 |
TTC8,NOXA1,NPHP3 |
| 2.688e-02 | -3.62 | TF_AP-2 | pfam domains | PF03299 | 5 | 3 | 16629 | 2504 |
TFAP2C,TFAP2A,TFAP2E |
| 2.688e-02 | -3.62 | ABC1 | pfam domains | PF03109 | 5 | 3 | 16629 | 2504 |
ADCK5,ADCK3,ADCK2 |
| 2.688e-02 | -3.62 | PQ-loop | pfam domains | PF04193 | 5 | 3 | 16629 | 2504 |
PQLC2,CTNS,PQLC3 |
| 2.688e-02 | -3.62 | HR1 | pfam domains | PF02185 | 5 | 3 | 16629 | 2504 |
RHPN2,PKN1,RHPN1 |
| 2.688e-02 | -3.62 | Lamp | pfam domains | PF01299 | 5 | 3 | 16629 | 2504 |
LAMP2,LAMP1,LAMP3 |
| 2.688e-02 | -3.62 | ABC2_membrane | pfam domains | PF01061 | 5 | 3 | 16629 | 2504 |
ABCG1,ABCG4,ABCG2 |
| 2.688e-02 | -3.62 | Choline_transpo | pfam domains | PF04515 | 5 | 3 | 16629 | 2504 |
SLC44A2,SLC44A1,SLC44A3 |
| 2.693e-02 | -3.61 | regulation of response to reactive oxygen species | biological process | GO:1901031 | 30 | 9 | 16441 | 2455 |
SESN3,TXN,PINK1,FBLN5,STK26,BMP7,NR4A3,HDAC6,SESN1 |
| 2.694e-02 | -3.61 | regulation of nucleocytoplasmic transport | biological process | GO:0046822 | 204 | 41 | 16441 | 2455 |
DDX58,TXN,NFKBIE,PPP1R12A,THRA,RAB23,PSMD10,TGFBR1,IL18,PRKACA,BARD1,APC2,IL18R1,IER3,NOV,CDH1,SP100,DACT1,BMP7,CABP1,SMO,DAB2IP,MDFIC,WNT3A,MAPK7,MDFI,CHP1,SIRT1,RHOA,PIK3R1,LITAF,PRKCQ,EGFR,FZD7,PTGS2,NFKBIA,WWTR1,INPP4B,PKD2,PKIA,TMEM173 |
| 2.702e-02 | -3.61 | TUBB (tubulin, beta class I) | protein interactions | 203068 | 214 | 45 | 16036 | 2547 |
INPPL1,TAOK2,PINK1,LGR4,TUBB4B,UBASH3B,CUL4B,TP53,CUL1,FBXO6,PKN1,HDAC6,LGALS3BP,ICAM1,SPP1,DPYSL2,PSMC2,TBCD,TUBG1,TNPO2,NCAM1,MAPK7,SYK,TUBA4A,LAMP2,MX1,PLK1,AKT1,CDC20,AGO4,IGSF8,AURKB,PKM,CBL,VCP,EGFR,MAGED2,HTT,TRAF3IP1,DCUN1D1,AURKA,ARRB1,MAL2,CD81,RNF146 |
| 2.704e-02 | -3.61 | soft_tissue-fat-liposarcoma | COSMIC cancer mutations | soft_tissue-fat-liposarcoma | 26 | 8 | 17775 | 2585 |
SS18,CTNNB1,AKT1,PIK3CA,TP53,ERBB2,IDH1,EGFR |
| 2.704e-02 | -3.61 | soft_tissue-nerve_sheath-schwannoma | COSMIC cancer mutations | soft_tissue-nerve_sheath-schwannoma | 26 | 8 | 17775 | 2585 |
NF2,CTNNB1,AKT1,PTEN,RET,PIK3CA,IDH1,EGFR |
| 2.704e-02 | -3.61 | mixed_carcinoma | COSMIC cancer mutations | mixed_carcinoma | 26 | 8 | 17775 | 2585 |
CTNNB1,FGFR2,PTEN,MSH2,PIK3CA,TP53,IDH1,EGFR |
| 2.706e-02 | -3.61 | CHANG_CORE_SERUM_RESPONSE_UP | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_UP | 203 | 40 | 17758 | 2588 |
CPEB4,ITGA6,APOO,SDC1,EMP2,FAM167A,CENPN,PDIA4,MAGOHB,CENPJ,CEP78,PLK4,UBE2J1,TUBG1,TNFRSF12A,HYLS1,NCEH1,MYBL1,NUP85,TUBA4A,RAB3B,HN1L,PLAUR,MYBL2,CCBL2,EZR,GGH,EIF2AK1,LOXL2,SKA1,SLC25A5,GPLD1,STK17A,CDCA4,UAP1,PLOD2,DCK,CORO1C,SLC25A40,MRPS28 |
| 2.712e-02 | -3.61 | glutamine family amino acid metabolic process | biological process | GO:0009064 | 65 | 16 | 16441 | 2455 |
GFPT1,GCLM,PRODH,GCLC,HAL,ASL,GGH,SLC1A3,OAT,AMDHD1,DDAH1,ALDH5A1,CTPS1,GOT1,GAD1,FAH |
| 2.712e-02 | -3.61 | cardiac septum development | biological process | GO:0003279 | 65 | 16 | 16441 | 2455 |
HES1,ACVR1,SALL4,GATA3,WHSC1,NOTCH2,SAV1,NPHP3,DHRS3,FGFR2,CYR61,LMO4,TBX1,SMO,CITED2,EGLN1 |
| 2.712e-02 | -3.61 | microtubule-based transport | biological process | GO:0010970 | 97 | 22 | 16441 | 2455 |
KIF3C,SOD1,LCA5,UXT,KLC2,KIF13A,RAB6A,APBA1,IFT27,SSX2IP,MAP1B,TTC21B,KIF5B,HTT,WDR19,TRAF3IP1,KLC3,SSNA1,NDE1,RPGR,COPG1,RASGRP1 |
| 2.714e-02 | -3.61 | regulation of cellular response to growth factor stimulus | biological process | GO:0090287 | 239 | 47 | 16441 | 2455 |
LTBP1,RUNX2,CDKN1C,CD63,XIAP,TP53,GATA3,TGFBR1,ZFYVE9,MECOM,NEO1,CD109,TGFBR3,ITGA3,CTNNB1,CYR61,NPNT,FAM20C,GPC3,VASN,DNM2,DAB2IP,NPTN,PPP1CA,C10orf54,CITED2,SPRY2,SULF2,SIRT1,HES1,ADAM17,CASK,FZD4,BCL9,FURIN,RNF165,ILK,ONECUT1,FGFR2,ACVRL1,TWSG1,SLC9A6,FGF18,PPP1CB,TOB1,ARNT,XDH |
| 2.718e-02 | -3.61 | Phospholipid metabolism | REACTOME pathways | R-HSA-1483257 | 146 | 31 | 8202 | 1235 |
PLA2G4A,MTM1,INPPL1,CDS2,LPGAT1,INPP5D,PNPLA2,PIK3R1,ETNK1,PHOSPHO1,PLD2,PLA2G16,LPIN3,CDIPT,SLC44A3,CDS1,INPP5E,PI4K2B,AGPAT2,PTEN,OCRL,SLC44A1,INPP4B,PIK3CA,DGAT2,SLC44A2,PIK3C2B,PIK3CD,PLD1,PIKFYVE,CHPT1 |
| 2.721e-02 | -3.60 | CKS2 (CDC28 protein kinase regulatory subunit 2) | protein interactions | 1164 | 24 | 8 | 16036 | 2547 |
CCNA2,CKS1B,CAMK1D,CCNB1,CCNB2,ESPL1,CDK1,CKS2 |
| 2.721e-02 | -3.60 | IL4R (interleukin 4 receptor) | protein interactions | 3566 | 24 | 8 | 16036 | 2547 |
IRS2,JAK1,STAT6,INPP5D,IL13RA1,CD40,JAK3,SOCS5 |
| 2.721e-02 | -3.60 | ARID4A (AT rich interactive domain 4A (RBP1-like)) | protein interactions | 5926 | 24 | 8 | 16036 | 2547 |
CCND1,RB1,CCNA2,RBL1,HDAC1,CCNB1,CDK1,MXD1 |
| 2.721e-02 | -3.60 | RHOD (ras homolog family member D) | protein interactions | 29984 | 24 | 8 | 16036 | 2547 |
ACVR1,PCBP3,C1orf198,DIAPH2,TGFBR1,ADCK5,PLXNA1,SPTB |
| 2.721e-02 | -3.60 | NCAPH2 (non-SMC condensin II complex subunit H2) | protein interactions | 29781 | 24 | 8 | 16036 | 2547 |
HLA-B,EGLN3,PNKD,NCAPG2,ALDH3A2,EGFR,SDF4,SMC4 |
| 2.721e-02 | -3.60 | TXNIP (thioredoxin interacting protein) | protein interactions | 10628 | 24 | 8 | 16036 | 2547 |
TXN,ITCH,PRKAA1,TP53,CDKN1B,HDAC1,KPNA2,FHL1 |
| 2.721e-02 | -3.60 | positive regulation of cell development | biological process | GO:0010720 | 442 | 81 | 16441 | 2455 |
FOXO6,EPHA4,RET,CAMK1D,GRM5,TP73,CTNNB1,CDKL5,IL6ST,BCL6,SMO,DNM2,DAB2IP,TWIST1,PACSIN1,TIAM1,TIMP2,DMTN,RHEB,ARHGAP35,IRX3,DPYSL3,FYN,GPRC5B,BHLHB9,PTK7,LIMK1,WWTR1,TRIOBP,EFNA5,NRG1,ITPKA,RGS14,COBL,GRN,BIN1,SERPINE2,ARHGEF7,ETV5,CRABP2,TEAD3,CALR,BMP2,ITGA3,GATA2,MEGF8,BMP7,BAX,PRKCI,TNFRSF12A,NPTN,WNT3A,NTN1,TLE6,RIMS2,FAM134C,EPB41L5,TGIF1,HES1,RHOA,MMD,RAPGEF2,ASPM,RGCC,HMG20B,PDE5A,KIF20B,ILK,MAP1B,SEMA4D,TMEM30A,CSF1,AURKA,GPER1,SOX8,ARPC2,ARSB,SHOX2,SEMA3A,L1CAM,FOXA1 |
| 2.722e-02 | -3.60 | AFFAR_YY1_TARGETS_UP | MSigDB lists | AFFAR_YY1_TARGETS_UP | 209 | 41 | 17758 | 2588 |
SLC2A4,CDKN1C,TAP1,BLCAP,BCL2L1,B4GALT4,SEPP1,SLC9A3R2,ICAM1,ABCD4,KIF5B,PDGFA,HSF2,GPC3,FJX1,ADAM15,TINAGL1,TTLL1,SULF2,DUSP1,PSRC1,CD55,PFKFB2,TCFL5,ALCAM,FOS,MYOM1,SPAG1,EGFR,STX3,EBF2,FAS,CASP7,PDLIM3,PLOD2,RND3,SLC27A3,JAK3,ABCA1,EHD1,DMPK |
| 2.723e-02 | -3.60 | male gonad development | biological process | GO:0008584 | 119 | 26 | 16441 | 2455 |
REC8,COL9A3,NKX3-1,ASPM,SOX9,BIK,GATA3,TFAP2C,TGFBR1,BCL2L1,FNDC3A,SDC1,SIX4,ICAM1,PRDX4,SGPL1,CCND1,PITX2,INSR,LRRC6,HOXA9,CTSV,CST3,BAX,MSH2,SOX8 |
| 2.723e-02 | -3.60 | development of primary male sexual characteristics | biological process | GO:0046546 | 119 | 26 | 16441 | 2455 |
REC8,COL9A3,NKX3-1,ASPM,SOX9,BIK,GATA3,TFAP2C,TGFBR1,BCL2L1,FNDC3A,SDC1,SIX4,ICAM1,PRDX4,SGPL1,CCND1,PITX2,INSR,LRRC6,HOXA9,CTSV,CST3,BAX,MSH2,SOX8 |
| 2.728e-02 | -3.60 | WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D | 628 | 109 | 17758 | 2588 |
CCNI,KLK10,IBTK,CPT2,ZNF28,BLCAP,PLXNA1,COMMD5,SPSB1,MOCS1,DENND2D,BCAP31,CDK14,ELMO2,PPME1,IL6ST,OSBPL3,GYS1,DIXDC1,PDIA6,CPE,CTH,CERS2,PLK1,PCGF5,SOD1,TMEM43,CASP9,TMEM98,ARHGDIB,PRKAR2B,ERP44,LOXL2,EAF2,GALNT7,PKMYT1,PPP1R14C,ZBTB7B,ABR,VCP,OPTN,SLC44A3,IRX3,OSBPL2,PLCG1,RBL1,HOXA9,WWTR1,SLC27A1,SPRY4,ITPKA,GLCCI1,ISOC1,PPP2R5D,PRKAR1A,DLAT,RUNX2,TM2D2,LGALS3,POC1B,SHPRH,ARHGEF7,SERPINB9,CCM2,ERI2,ARHGEF40,AIP,CORO1B,WWP2,TOP2A,RB1,ADD3,SPIN4,BHLHE41,TMBIM6,ABCD1,MDFIC,KNTC1,AK3,HEXIM2,CITED2,FAIM,ALS2CL,NAGPA,PGM1,PCCB,ALDH2,PLSCR1,FBXO9,TTC7A,GRTP1,EPN3,GNAS,INSR,PRKAG2,DGCR2,TRIM69,DCK,ITGA7,NR4A3,FGD6,DYSF,UACA,GLB1,ARSB,JAK3,TOB1,PTGES,FBXW5 |
| 2.732e-02 | -3.60 | cellular response to light stimulus | biological process | GO:0071482 | 108 | 24 | 16441 | 2455 |
SIRT1,DDB2,PBK,CUL4B,CALM1,PIK3R1,CASP9,TP53,CALM3,PRKCQ,AURKB,NMT2,TP73,CALM2,RGS9,PTGS2,PCNA,FNTA,GNB5,BAX,CRY2,CNGA1,RPGR,METAP2 |
| 2.733e-02 | -3.60 | AMIT_SERUM_RESPONSE_240_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_240_MCF10A | 56 | 14 | 17758 | 2588 |
PRSS8,ARHGEF3,PRKAG2,B3GNT2,CDKN1C,CDH1,PVRL2,ALDH1A3,MAP3K11,EZR,PKP2,BCL2L1,B4GALT4,OCLN |
| 2.733e-02 | -3.60 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | 56 | 14 | 17758 | 2588 |
IRS2,TNS3,TRAM2,PBK,TMX4,ARL4C,CD9,KCNS3,MORC4,SGK1,COL18A1,ARRB1,PRKAR2B,MAP1LC3B |
| 2.733e-02 | -3.60 | PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP | MSigDB lists | PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP | 56 | 14 | 17758 | 2588 |
HMMR,CDKN2C,CENPA,FOXM1,CDC20,NDC80,MYBL2,MSH2,AURKA,USP1,AURKB,CDK1,LBR,SMC4 |
| 2.733e-02 | -3.60 | GCM_PTPRD | MSigDB lists | GCM_PTPRD | 56 | 14 | 17758 | 2588 |
SCARB2,TRIM8,GPRC5B,ANKS1B,FRYL,BACE1,KIAA1109,DNAJB14,NDRG3,ULK2,NIPA1,CCDC88A,MAP1B,DOCK9 |
| 2.733e-02 | -3.60 | KORKOLA_YOLK_SAC_TUMOR | MSigDB lists | KORKOLA_YOLK_SAC_TUMOR | 56 | 14 | 17758 | 2588 |
MDK,BMP2,SMARCA2,CEP70,METTL7A,VANGL1,FRAS1,FLRT3,NMI,NEK2,NRG1,FZD5,B4GALT4,CYP26A1 |
| 2.733e-02 | -3.60 | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN | MSigDB lists | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN | 56 | 14 | 17758 | 2588 |
BCAR3,SYPL1,SWAP70,ALDH5A1,MMD,CCDC6,CD22,DBI,CAPG,AES,CD40,GSTP1,ETS1,TRAF5 |
| 2.736e-02 | -3.60 | IKEDA_MIR30_TARGETS_DN | MSigDB lists | IKEDA_MIR30_TARGETS_DN | 26 | 8 | 17758 | 2588 |
MMD,PANK1,PRICKLE1,IRX4,STK39,ANO4,PPP1R14C,NCAM1 |
| 2.736e-02 | -3.60 | EINAV_INTERFERON_SIGNATURE_IN_CANCER | MSigDB lists | EINAV_INTERFERON_SIGNATURE_IN_CANCER | 26 | 8 | 17758 | 2588 |
MX1,TGIF1,SP100,STAT1,IFIT1,IFIT3,APOBEC3G,IFI6 |
| 2.736e-02 | -3.60 | BIOCARTA_VIP_PATHWAY | MSigDB lists | BIOCARTA_VIP_PATHWAY | 26 | 8 | 17758 | 2588 |
CALM2,PLCG1,CALM1,NFKBIA,CALM3,PRKAR2B,EGR3,PRKAR1A |
| 2.736e-02 | -3.60 | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | MSigDB lists | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | 26 | 8 | 17758 | 2588 |
CCND1,RB1,RUNX2,SERPINA1,BCL6,CDKN1B,MAPK12,FAS |
| 2.736e-02 | -3.60 | WILLIAMS_ESR1_TARGETS_UP | MSigDB lists | WILLIAMS_ESR1_TARGETS_UP | 26 | 8 | 17758 | 2588 |
CCNA2,KCNK5,CDC20,FAM83D,BUB1,RNASEH2A,WDR62,TUBA4A |
| 2.742e-02 | -3.60 | L-ascorbic acid binding | molecular function | GO:0031418 | 21 | 7 | 16491 | 2452 |
PLOD3,EGLN3,PLOD2,P4HA2,P3H2,P4HA3,EGLN1 |
| 2.748e-02 | -3.59 | acetylgalactosaminyltransferase activity | molecular function | GO:0008376 | 35 | 10 | 16491 | 2452 |
CHSY3,GALNT3,B3GALNT1,GALNT12,CSGALNACT1,C1GALT1C1,GALNT7,B3GALNT2,CHPF,B4GALNT1 |
| 2.750e-02 | -3.59 | LNR | prosite domains | PS50258 | 5 | 3 | 11866 | 1802 |
NOTCH2,NOTCH3,GNPTAB |
| 2.750e-02 | -3.59 | BRO1 | prosite domains | PS51180 | 5 | 3 | 11866 | 1802 |
RHPN2,BROX,RHPN1 |
| 2.751e-02 | -3.59 | PID_ERBB1_DOWNSTREAM_PATHWAY | MSigDB lists | PID_ERBB1_DOWNSTREAM_PATHWAY | 105 | 23 | 17758 | 2588 |
AKT1,IQGAP1,EPS8,PIK3R1,PLD2,BCL2L1,NCKAP1,CYFIP2,ELK1,FOS,EGFR,ARF4,CAPN2,ZFP36,STAT1,PIK3CA,PLD1,PIK3CD,MAPK7,ARPC2,GAB1,RPS6KA3,DUSP1 |
| 2.754e-02 | -3.59 | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | 168 | 34 | 17758 | 2588 |
EXPH5,NUDT6,FAM169A,BIK,HABP4,ABCG2,ZNRF3,ITPR2,PHLPP1,TRIB2,SEPT4,MERTK,TNFRSF19,ZNF385B,CYP1A1,ANKFN1,RUNDC3B,AOX1,TMEM64,TTPA,MYRIP,ALDH3A2,ADRBK2,IRX3,FAS,SEC14L2,HLF,SLC4A4,KCNK1,RAB11FIP2,NKD1,TTC9,SLC25A30,CPPED1 |
| 2.754e-02 | -3.59 | MODULE_308 | MSigDB lists | MODULE_308 | 72 | 17 | 17758 | 2588 |
SMARCA2,DEPDC1,CDKN1C,FOXM1,PTPN9,MYBL2,ATP8B3,CCNB1,CDC25C,SETDB2,SH3BP1,GTF2F2,E2F1,AK3,PHKA2,GFI1,ZBTB33 |
| 2.761e-02 | -3.59 | V$RORA1_01 | MSigDB lists | V$RORA1_01 | 233 | 45 | 17758 | 2588 |
NCKAP5,KCNAB3,TAB3,SLC25A27,FHDC1,NDRG2,CYP39A1,PSIP1,TSPAN7,CMTM6,NEO1,HDAC9,ZDHHC21,CCDC92,VASP,ZNF687,DACT1,STEAP2,ESPN,ACSL4,PIM1,PACSIN1,ZRANB1,BTBD3,CCDC88A,GPR161,CTH,WDR72,CXXC5,LCA5,BCL9,RGAG1,STRADB,TCF7,UBAC1,LDB2,ZFAND5,GABARAPL1,MPRIP,STK38,MYLK,ARF6,PPP2R5D,RTN3,JARID2 |
| 2.763e-02 | -3.59 | Signaling by Hedgehog | REACTOME pathways | R-HSA-5358351 | 135 | 29 | 8202 | 1235 |
ADAM17,ERLEC1,PSMB4,PSME2,ITCH,PSMD7,CUL1,PSMD10,PRKAR2B,PSME1,NOTUM,PRKACA,PSMA4,VCP,GNAS,TTC21B,PSMD1,ADRBK1,P4HB,IQCE,PSMD3,WDR19,PSMC2,SMO,ARRB1,PSMC1,PSMA5,GPR161,PRKAR1A |
| 2.764e-02 | -3.59 | ATTCTTT,MIR-186 | MSigDB lists | ATTCTTT,MIR-186 | 263 | 50 | 17758 | 2588 |
FRMD4A,CPEB4,CAST,CTSB,ITGA6,XIAP,OSGIN2,P2RX7,TRAPPC8,CNTNAP2,RAB6A,SPSB1,EXT2,NFAT5,PLS3,APLP2,PDCD10,FICD,MITF,TRPC1,RGS5,ACSL4,FAR1,BTBD3,MYT1,NCOA2,TMED2,PDGFC,CXXC5,ZC3H11A,PAPD7,BCL9,SAT1,RNF11,DPP9,MCFD2,FNDC3A,ICMT,SP4,SGPP1,BCAR3,CNTNAP1,MAP2,HOXA9,PPP1CB,NR4A2,CPEB2,NR3C2,TOB1,RPS6KA3 |
| 2.767e-02 | -3.59 | axon | cellular component | GO:0030424 | 370 | 68 | 17570 | 2579 |
GRIK2,IQGAP1,EPHA4,RET,HDAC6,NCS1,NOV,DPYSL2,DLG1,DAB2IP,GOT1,MYH14,SCN2A,PACSIN1,ATL1,CLCN3,MBP,SEPT6,CCSAP,SYP,TANC1,ALCAM,DAG1,IRX3,SLC9A6,STAT1,NRG1,NRGN,COBL,BIN1,ANXA3,LMTK3,PINK1,BACE1,CALB2,GABRG2,CNTNAP2,KCNC4,ANK1,IGSF9,CA2,ADORA1,FLRT3,KIF13B,CST3,CPLX1,HCN3,P2RX4,RHOA,GRIN1,STMN3,KIF20B,ILK,ELK1,NFIB,MAPK8IP1,CDK5R1,IL1R1,CNTNAP1,LDLRAP1,HTT,SYT7,AURKA,ACADM,GPER1,SEMA3A,L1CAM,DRD1 |
| 2.767e-02 | -3.59 | KAAB_HEART_ATRIUM_VS_VENTRICLE_DN | MSigDB lists | KAAB_HEART_ATRIUM_VS_VENTRICLE_DN | 257 | 49 | 17758 | 2588 |
LMO7,PINK1,CDKN1C,NUAK1,GCAT,PKP2,SLC1A3,ECI1,PPP2R3A,COX7A2,CAPN2,FLII,PAIP2B,STIM1,BDH1,GYS1,WWP1,LIMCH1,MCCC2,TUBA4A,PGM1,MAPKAPK3,RAPGEF2,LYRM1,FHL2,AK4,CAPNS1,UBAC1,ATP1B1,DPYSL4,MYL12A,PDHX,CYB5A,GNAS,ALDH5A1,PRDX3,TBX1,FGF18,ALPK3,STK39,RCAN2,MAP3K5,TMEM159,TBC1D4,HIPK3,TOB1,GAB1,PKIA,CSRP2 |
| 2.769e-02 | -3.59 | myoepithelial_carcinoma | COSMIC cancer mutations | myoepithelial_carcinoma | 17 | 6 | 17775 | 2585 |
ERBB2,CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 2.769e-02 | -3.59 | salivary_gland-carcinoma-myoepithelial_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-myoepithelial_carcinoma | 17 | 6 | 17775 | 2585 |
ERBB2,CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 2.769e-02 | -3.59 | verrucal_keratosis_BRAF_inhibitor_related | COSMIC cancer mutations | verrucal_keratosis_BRAF_inhibitor_related | 17 | 6 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA |
| 2.769e-02 | -3.59 | skin-non_chronically_sun_exposed_site-malignant_melanoma | COSMIC cancer mutations | skin-non_chronically_sun_exposed_site-malignant_melanoma | 17 | 6 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA |
| 2.769e-02 | -3.59 | salivary_gland-carcinoma-salivary_duct_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-salivary_duct_carcinoma | 17 | 6 | 17775 | 2585 |
ERBB2,CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 2.769e-02 | -3.59 | adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | adult_T_cell_lymphoma-leukaemia | 17 | 6 | 17775 | 2585 |
RB1,CTNNB1,JAK1,FLT3,JAK3,TP53 |
| 2.769e-02 | -3.59 | squamous_cell_carcinoma_BRAF_inhibitor_related | COSMIC cancer mutations | squamous_cell_carcinoma_BRAF_inhibitor_related | 17 | 6 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA |
| 2.769e-02 | -3.59 | skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | 17 | 6 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA |
| 2.769e-02 | -3.59 | breast-carcinoma-neuroendocrine_carcinoma | COSMIC cancer mutations | breast-carcinoma-neuroendocrine_carcinoma | 17 | 6 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA |
| 2.769e-02 | -3.59 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | 17 | 6 | 17775 | 2585 |
RB1,CTNNB1,JAK1,FLT3,JAK3,TP53 |
| 2.769e-02 | -3.59 | skin-other-verrucal_keratosis_BRAF_inhibitor_related | COSMIC cancer mutations | skin-other-verrucal_keratosis_BRAF_inhibitor_related | 17 | 6 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA |
| 2.769e-02 | -3.59 | lower_extremity | COSMIC cancer mutations | lower_extremity | 17 | 6 | 17775 | 2585 |
CTNNB1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 2.769e-02 | -3.59 | non_chronically_sun_exposed_site | COSMIC cancer mutations | non_chronically_sun_exposed_site | 17 | 6 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA |
| 2.769e-02 | -3.59 | upper_extremity | COSMIC cancer mutations | upper_extremity | 17 | 6 | 17775 | 2585 |
CTNNB1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 2.770e-02 | -3.59 | vif (p23) | protein interactions | 155459 | 320 | 64 | 16036 | 2547 |
PSME2,XYLT1,SOD2,TP53,PSME1,CCNB1,PRKACA,MAP1LC3B,SPSB1,MNS1,APOBEC3B,PSMD1,PSMC2,IL31RA,APOBEC3G,SCN3A,ATG4D,APOBEC3D,TCEB2,ITCH,SAT1,CR2,PRKAR2B,TMTC2,CDK1,AREG,PSMD3,TLE1,PSMC1,PRKAR1A,PRKAA2,KLF2,RUNX2,ITGA6,DNAJB2,PRKAA1,PSMD7,PSMD10,APOBEC3H,ATG4A,ADD3,GATA2,SLC16A6,ULBP2,PSMA5,DUSP1,PSMB4,IFITM3,PCBP3,LITAF,MAML2,RUNX3,IFIT3,PSMA4,MAP1B,RND3,CSF1,ISM1,UBE2D2,UACA,NR4A2,MAP3K5,IRF1,EGLN1 |
| 2.770e-02 | -3.59 | GK/Ca_channel_bsu | interpro domains | IPR008145 | 26 | 8 | 18293 | 2672 |
CASK,TJP3,MPP1,DLG1,MPP2,MPP5,DLG3,CACNB4 |
| 2.774e-02 | -3.58 | cellular modified amino acid metabolic process | biological process | GO:0006575 | 216 | 43 | 16441 | 2455 |
PLA2G4A,GCLM,DHPS,CRYM,MGST2,PLA2G16,GSTP1,P4HB,SLC46A1,SERINC2,PCYOX1,ALDH7A1,AHCY,APIP,ETHE1,EGLN3,CRTAP,CTH,OPLAH,PRODH,SOD1,SHMT1,PLSCR1,GCLC,PANK1,ERO1A,CCBL2,GGH,GLO1,ICMT,IDH1,PRDX4,DUOX1,DDAH1,SLCO4A1,ALDH5A1,CTNS,ABHD12,HTT,P4HA2,SLC27A1,OCLN,EGLN1 |
| 2.780e-02 | -3.58 | MHC class II antigen presentation | REACTOME pathways | R-HSA-2132295 | 102 | 23 | 8202 | 1235 |
SEC23A,KIF3C,KIF20A,CTSB,KLC2,KIF23,RACGAP1,KIF2C,KIF26A,KIF11,DCTN6,KIF5B,CTSL,AP1M2,CTSC,CTSV,DNM2,KLC3,KIF22,CTSA,CENPE,LGMN,CTSD |
| 2.781e-02 | -3.58 | UBE2N (ubiquitin conjugating enzyme E2N) | protein interactions | 7334 | 144 | 32 | 16036 | 2547 |
SLC2A4,TRIM5,SHPRH,TRAF2,XIAP,TP53,RNF182,ZNRF3,PJA2,BARD1,RAD23A,SH3RF2,VASP,RNF128,ZNRF2,MKRN3,CADPS2,MYLIP,PCCB,UFD1L,AMFR,RC3H2,RNF11,RNF165,F12,PELI3,ARF4,BCL10,OTUB2,AURKA,CAB39,HSPB1 |
| 2.782e-02 | -3.58 | thyroid-carcinoma-medullary_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-medullary_carcinoma | 300 | 56 | 17775 | 2585 |
FRMPD3,TMEM55B,RET,TP53,ERBB2,PKP2,NUCB2,FLT3,RBP7,STIL,LTBP3,SAP130,CDKN2C,RB1,DOPEY2,NUP210,CTNNB1,CDH1,PTEN,KIF14,CALD1,SMO,PRKG1,PIK3CA,TFG,MYBL1,NR2C1,SULF2,ZNF462,SPEF2,AKT1,PARD3B,ASPM,MGAM,PRICKLE1,IDH1,GNA11,EGFR,GNAS,CRTC2,PTPRJ,FGFR2,CCDC6,INPP4B,APPL2,GLB1,SYT13,TRPC3,JAK3,TOB1,ABCA1,ARNT,CXorf56,ADAMTS16,DOCK9,PRKAR1A |
| 2.782e-02 | -3.58 | medullary_carcinoma | COSMIC cancer mutations | medullary_carcinoma | 300 | 56 | 17775 | 2585 |
FRMPD3,TMEM55B,RET,TP53,ERBB2,PKP2,NUCB2,FLT3,RBP7,STIL,LTBP3,SAP130,CDKN2C,RB1,DOPEY2,NUP210,CTNNB1,CDH1,PTEN,KIF14,CALD1,SMO,PRKG1,PIK3CA,TFG,MYBL1,NR2C1,SULF2,ZNF462,SPEF2,AKT1,PARD3B,ASPM,MGAM,PRICKLE1,IDH1,GNA11,EGFR,GNAS,CRTC2,PTPRJ,FGFR2,CCDC6,INPP4B,APPL2,GLB1,SYT13,TRPC3,JAK3,TOB1,ABCA1,ARNT,CXorf56,ADAMTS16,DOCK9,PRKAR1A |
| 2.783e-02 | -3.58 | response to light stimulus | biological process | GO:0009416 | 352 | 66 | 16441 | 2455 |
DYNLRB1,CASP3,AGRN,HSPG2,CUL4B,TP53,CACNB4,SDC1,SDF4,CDS1,TP73,CALM2,CCND1,PCNA,DNM2,CRY2,PPP1CA,SCARA3,CDKN2D,METAP2,SIRT1,AKT1,PBK,CASP9,SPRTN,PRKCQ,AURKB,TANC1,PLEKHB1,PTGS2,PPP1CB,RGS14,PRKAA1,SDC4,CALM3,SLC1A3,DHRS3,GNB5,GPC3,OPN3,BAX,MSH2,USP1,CNGA1,ERCC2,RPGR,MSH6,DUSP1,DDB2,PIK3R1,CALM1,GRIN1,UBE2A,ELK1,FOS,GNA11,NMT2,EGFR,FECH,RGS9,FNTA,CTNS,HTT,ARRB1,TRPC3,DRD1 |
| 2.784e-02 | -3.58 | organic substance transport | biological process | GO:0071702 | 1891 | 311 | 16441 | 2455 |
SLC35D2,ACACB,GRIK2,SLC25A13,ATP8A1,TAP1,GATA3,TRAPPC8,SYTL4,SNX9,PICK1,NAPG,PQLC2,AP1M2,OSBPL3,SLC46A1,SERINC2,DNM2,SNX16,LAMP2,VPS11,KDELR3,SLC35C1,KIF13A,SLC17A5,ICMT,MCFD2,SLC25A5,RNF19B,SPNS3,RAB2B,ARF4,SLC25A4,GNPTAB,NOD2,ARF6,F2RL1,NXT2,NFKBIE,GGA1,SEC61G,RAB23,SLC36A4,SLC1A3,APBA1,FAM21C,LMNA,ATG4A,CALR,DOPEY2,SNX18,RPL39,SLC16A6,NECAB3,FBXO7,SORL1,CADPS2,SYTL3,NUP85,TMED2,RIMS2,TRAK2,NAGPA,PMPCB,UFD1L,GCC2,SLC37A1,KIF20A,ANO6,CALCRL,PLS1,NPC2,SRSF5,ATP8B3,PCTP,GOLT1A,SFXN5,RHOB,STX3,SLCO4A1,AP1AR,SCARB2,PRKAG2,SLC4A4,TIMM8A,HTT,ZDHHC20,SLC4A3,HOOK1,NUP58,EHD1,PLA2G4A,MTM1,SLC2A4,APOO,C5orf30,MVB12B,ZFYVE9,APPBP2,TNPO2,IFIT1,ACSL4,OSBPL7,ARL4D,RAB27B,SNX10,ATG4D,MYO5B,SNX8,SEC23A,SLC5A11,SEC61B,COG2,FZD4,DMTN,VPS4B,SLC11A2,ATP1B1,RAB38,SNX12,ATP10D,OSBPL2,PEX5,STX10,DDOST,SLC27A1,RAB29,TTC8,HSP90B1,TAOK2,SLC16A14,ATP9A,FLOT1,BTN3A1,PDIA3,ANO9,IFT27,PDIA4,CKAP5,SLC25A36,ANK1,SLC27A6,PPP1R10,FAM160A2,ATP8B1,SLC44A2,SLC16A5,NCOA2,LCA5,ZC3H11A,DENND1B,PIK3R1,EIF5A2,VAMP3,RAB3IP,YES1,NEURL1B,CPTP,RGPD5,LDLRAP1,MAMDC4,RPL12,CTNS,RAB11FIP2,ARFGAP3,NUP37,SRSF9,ESYT2,EXPH5,UNC93B1,FAF2,CRYM,CPT2,ARFGEF1,UBE2Q1,HDAC6,CACNB4,ERP29,NUP62CL,ZFYVE16,MAGOHB,RAB15,NUP210,RABEP2,LMAN2L,SLC44A1,ABCA2,RAB20,RP2,CTTN,ANO4,MYRIP,TRAM1,S100A13,EZR,ARFRP1,ESYT1,TCN2,VCP,OPTN,EDNRA,TRAM2,TBC1D17,UEVLD,RAB11FIP1,KPNA2,APBA2,PCSK5,PRKAA2,PEX6,SLC22A31,ABCG2,ATP6V1E2,RAB6A,PGAP1,CA2,RINL,KIF13B,KCNN4,FRAS1,EXOC8,PRKCI,SRP54,KDELR1,SNX7,STRADB,BTN3A2,ZDHHC3,GNAS,TSC1,SLC6A6,TMEM30A,MFSD2A,NFKBIA,SLC2A6,SH3BP4,RAB31,ZDHHC7,CTSA,PITPNA,LTBP2,JAK3,APOL2,TOB1,SNX30,DRD1,SLC25A24,SORBS1,UPF3B,SLC2A8,ABCG4,TP53,P2RX7,SLC7A2,BCAP31,SYTL2,ATP6V0B,SVBP,ZDHHC12,FABP6,ZDHHC23,BCL6,RPN2,STEAP3,LMAN1,F2R,GM2A,UPF3A,CHP1,SOAT1,AKT1,AP5M1,DAG1,TAPBP,PEX2,CHMP4B,RPL22,ABCA1,COPG1,SORT1,CD63,AIP,VPS26A,ZDHHC21,M6PR,SNX13,MLPH,ADORA1,CDK16,RRBP1,SLC35B4,TRIM3,CPLX1,ABCD1,SYK,SLC35A1,RPGR,CAMK2G,MYO5A,HES1,RAB3B,PPARA,PRICKLE1,BBS2,SCG2,ARRB1,SPCS3,ATP6V1C1,CEP41,RAB3IL1,ABCG1 |
| 2.789e-02 | -3.58 | GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN | MSigDB lists | GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN | 174 | 35 | 17758 | 2588 |
GAS2L1,HECA,SORBS1,PAPSS2,CRYM,FXYD3,SORBS3,TRIB2,PGAP1,CDKN2C,ANK1,ENTPD4,SCNN1A,CD22,KLF3,VAT1,WWP1,ECE1,TIAM1,ALS2CL,TPCN1,NCOA2,SEMA3B,P2RX4,PAPD7,MPP1,RASGRP2,ONECUT1,PLCH1,ATP1A1,PVRL2,TBX1,SECTM1,CSGALNACT1,CD33 |
| 2.793e-02 | -3.58 | GGCAGTG,MIR-324-3P | MSigDB lists | GGCAGTG,MIR-324-3P | 94 | 21 | 17758 | 2588 |
MBP,FZD4,CIT,ETV5,COL7A1,FTH1,RAB6A,SLC20A1,DAG1,EDNRA,PIAS3,SHROOM3,WDR44,FGFR2,FAM160A2,PTER,RIMS3,RAP2C,PLXND1,RGS14,ABCA1 |
| 2.796e-02 | -3.58 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_3 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_3 | 17 | 6 | 17758 | 2588 |
PKP2,LMO7,CPEB4,F2RL1,MYL12A,EGFR |
| 2.796e-02 | -3.58 | APICAL_PART_OF_CELL | MSigDB lists | APICAL_PART_OF_CELL | 17 | 6 | 17758 | 2588 |
ATP8B1,USH1C,SHROOM2,SHROOM3,STX3,SLC46A1 |
| 2.796e-02 | -3.58 | LOPEZ_MBD_TARGETS_IMPRINTED_AND_X_LINKED | MSigDB lists | LOPEZ_MBD_TARGETS_IMPRINTED_AND_X_LINKED | 17 | 6 | 17758 | 2588 |
ABCD1,MTM1,IRAK1,GPC3,UBE2A,NXT2 |
| 2.796e-02 | -3.58 | BIOCARTA_IL7_PATHWAY | MSigDB lists | BIOCARTA_IL7_PATHWAY | 17 | 6 | 17758 | 2588 |
FYN,JAK1,JAK3,NMI,PIK3R1,PIK3CA |
| 2.796e-02 | -3.58 | LAMB_CCND1_TARGETS | MSigDB lists | LAMB_CCND1_TARGETS | 17 | 6 | 17758 | 2588 |
KIF22,EFNA1,HSPG2,RPS6KA1,LGALS3BP,RAB31 |
| 2.796e-02 | -3.58 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | MSigDB lists | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | 17 | 6 | 17758 | 2588 |
PLCG1,CBL,GAB1,EGFR,PIK3R1,PIK3CA |
| 2.796e-02 | -3.58 | chr6p23 | MSigDB lists | chr6p23 | 17 | 6 | 17758 | 2588 |
GMPR,RNF182,KIF13A,MYLIP,RANBP9,CD83 |
| 2.796e-02 | -3.58 | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_DN | MSigDB lists | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_DN | 17 | 6 | 17758 | 2588 |
GAA,NFKBIZ,C10orf54,HSP90B1,IL6ST,CBX7 |
| 2.796e-02 | -3.58 | KAPOSI_LIVER_CANCER_MET_UP | MSigDB lists | KAPOSI_LIVER_CANCER_MET_UP | 17 | 6 | 17758 | 2588 |
FGD6,HMGA1,ITGAV,CD63,CKS2,MDFI |
| 2.796e-02 | -3.58 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | MSigDB lists | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | 17 | 6 | 17758 | 2588 |
CALM2,CALM3,GRIN2D,RASGRF1,CALM1,GRIN1 |
| 2.796e-02 | -3.58 | NEGATIVE_REGULATION_OF_CELL_ADHESION | MSigDB lists | NEGATIVE_REGULATION_OF_CELL_ADHESION | 17 | 6 | 17758 | 2588 |
ARHGDIB,NF2,PTEN,ACVRL1,RASA1,RND1 |
| 2.796e-02 | -3.58 | BIOCARTA_ERK5_PATHWAY | MSigDB lists | BIOCARTA_ERK5_PATHWAY | 17 | 6 | 17758 | 2588 |
PLCG1,AKT1,MAPK7,RPS6KA1,PIK3R1,PIK3CA |
| 2.796e-02 | -3.58 | BIOCARTA_ARF_PATHWAY | MSigDB lists | BIOCARTA_ARF_PATHWAY | 17 | 6 | 17758 | 2588 |
TWIST1,RB1,PIK3R1,PIK3CA,E2F1,TP53 |
| 2.797e-02 | -3.58 | regulation of protein import | biological process | GO:1904589 | 170 | 35 | 16441 | 2455 |
DDX58,TXN,NFKBIE,THRA,RAB23,PSMD10,TGFBR1,IL18,APC2,IL18R1,NOV,CDH1,DACT1,BMP7,CABP1,SMO,DAB2IP,MDFIC,WNT3A,MAPK7,MDFI,CHP1,SIRT1,RHOA,PIK3R1,LITAF,PRKCQ,FZD7,EGFR,PTGS2,NFKBIA,WWTR1,PKD2,PKIA,TMEM173 |
| 2.797e-02 | -3.58 | HSPG2 (heparan sulfate proteoglycan 2) | protein interactions | 3339 | 33 | 10 | 16036 | 2547 |
GRN,PDGFA,CTGF,COL13A1,BMP1,VWA1,TINAGL1,FBXO6,PDGFB,FBLN1 |
| 2.797e-02 | -3.58 | PTPN23 (protein tyrosine phosphatase, non-receptor type 23) | protein interactions | 25930 | 33 | 10 | 16036 | 2547 |
KIF5B,LGR4,KLC2,TUBG1,AURKA,CHMP4B,ALG2,VPS26A,VCP,EGFR |
| 2.797e-02 | -3.58 | LIMK1 (LIM domain kinase 1) | protein interactions | 3984 | 33 | 10 | 16036 | 2547 |
MAPKAPK2,SSH3,MBP,CDKN1C,SSH1,LIMK1,PAK2,ARRB1,NRG1,ABCA1 |
| 2.797e-02 | -3.58 | CRY1 (cryptochrome circadian clock 1) | protein interactions | 1407 | 33 | 10 | 16036 | 2547 |
GRN,PLSCR1,NR1D2,TRAF2,BHLHE41,CUL1,PER3,PPP2R5D,PER2,MDFI |
| 2.797e-02 | -3.58 | DOK4 (docking protein 4) | protein interactions | 55715 | 33 | 10 | 16036 | 2547 |
FYN,INSR,IGF1R,PBK,RET,ERBB2,PHKA2,PHKG2,RASA1,EGFR |
| 2.797e-02 | -3.58 | S100A7 (S100 calcium binding protein A7) | protein interactions | 6278 | 33 | 10 | 16036 | 2547 |
SUSD3,WIPI1,CUL4B,RASSF7,DCUN1D1,IFIT1,TFG,CA8,RANBP9,EGFR |
| 2.801e-02 | -3.58 | histone H3 deacetylation | biological process | GO:0070932 | 21 | 7 | 16441 | 2455 |
ELK4,HDAC1,SIRT1,HDAC6,HDAC11,PER2,HDAC9 |
| 2.801e-02 | -3.58 | phosphatidylinositol dephosphorylation | biological process | GO:0046856 | 21 | 7 | 16441 | 2455 |
INPP5E,MTM1,INPPL1,PTEN,INPP5D,OCRL,TMEM55B |
| 2.801e-02 | -3.58 | Sertoli cell differentiation | biological process | GO:0060008 | 21 | 7 | 16441 | 2455 |
SOX8,FNDC3A,SDC1,CTSV,CST3,ICAM1,SOX9 |
| 2.801e-02 | -3.58 | positive regulation of nucleoside metabolic process | biological process | GO:0045979 | 21 | 7 | 16441 | 2455 |
PRKAA2,P2RX7,PINK1,INSR,ARNT,VCP,PRKAA1 |
| 2.801e-02 | -3.58 | ectoderm development | biological process | GO:0007398 | 21 | 7 | 16441 | 2455 |
EPB41L5,NF2,ETS2,CTNNB1,ZBTB7B,ITGA6,ELF5 |
| 2.801e-02 | -3.58 | regulation of membrane protein ectodomain proteolysis | biological process | GO:0051043 | 21 | 7 | 16441 | 2455 |
TIMP2,TIMP3,TIMP1,SNX9,SH3D19,GPLD1,FURIN |
| 2.801e-02 | -3.58 | chondrocyte development | biological process | GO:0002063 | 21 | 7 | 16441 | 2455 |
RUNX2,SHOX2,IMPAD1,RARG,FGF18,SOX9,SULF2 |
| 2.801e-02 | -3.58 | positive regulation of ATP metabolic process | biological process | GO:1903580 | 21 | 7 | 16441 | 2455 |
PRKAA2,P2RX7,PINK1,INSR,ARNT,VCP,PRKAA1 |
| 2.801e-02 | -3.58 | relaxation of muscle | biological process | GO:0090075 | 21 | 7 | 16441 | 2455 |
P2RX4,PDE5A,SOD1,ATP1A1,ATP1B1,ADORA1,PRKG1 |
| 2.801e-02 | -3.58 | tongue development | biological process | GO:0043586 | 21 | 7 | 16441 | 2455 |
HDAC1,ERBB2,WNT10B,CTNNB1,TBX1,SIX4,HOXC13 |
| 2.801e-02 | -3.58 | cellular response to osmotic stress | biological process | GO:0071470 | 21 | 7 | 16441 | 2455 |
CAB39,SERPINB6,STK39,PKD2,SLC2A4,SCN2A,MYLK |
| 2.806e-02 | -3.57 | E2F3 (E2F transcription factor 3) | protein interactions | 1871 | 47 | 13 | 16036 | 2547 |
RB1,PCNA,CCNA2,RBL1,UXT,MYBL2,MSH2,BCL6,FHL2,HDAC1,CCNB1,CDK1,TEAD3 |
| 2.806e-02 | -3.57 | SIN3B (SIN3 transcription regulator family member B) | protein interactions | 23309 | 47 | 13 | 16036 | 2547 |
TFAP4,SMARCA2,RNF220,NR1D2,SUDS3,TP53,HDAC1,WHSC1,MORF4L2,MYT1,SMN1,MXD1,HDAC9 |
| 2.807e-02 | -3.57 | somatodendritic compartment | cellular component | GO:0036477 | 593 | 104 | 17570 | 2579 |
LAMP1,NQO1,GRIK2,EPHA4,RET,FBXO2,P2RX7,LYNX1,HDAC6,DNER,GRM5,NCS1,NOV,CDKL5,IL6ST,CABP1,DPYSL2,SRR,DAB2IP,PPP1CA,CTTN,ACSL4,DLG3,CPE,SGCE,SOD1,TIMP2,MBP,PRKAR2B,ITPR3,TANC1,ALCAM,ARF4,GABARAPL1,PIAS3,TRIM9,GRID2IP,MAP2,KCNK1,PLK2,WFS1,SLC9A6,SIPA1L1,STAT1,NRG1,ITPKA,RGS14,NRGN,COBL,LZTS1,ANXA3,FARP1,SORT1,LMTK3,TAOK2,CPEB4,ENO2,SERPINE2,ARHGEF7,LRP4,STRN4,SLC25A27,SLC1A3,CAPN2,ADORA1,MLPH,IGSF9,SNX18,PTEN,ANKS1B,KNDC1,KCNN4,MAGEE1,CST3,CPLX1,MYO5A,HCN3,DPYSL5,P2RX4,MOB4,ZWINT,RAPGEF2,SHARPIN,GRIN1,FXR2,ILK,ELK1,MAPK8IP1,CDK5R1,STX3,PDE11A,MAP1B,GNAS,PTPRF,HTT,CTSV,S100A5,AURKA,ARRB1,GRIN2D,GPER1,SHROOM2,SEMA3A,DRD1 |
| 2.810e-02 | -3.57 | NEDD4 (neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase) | protein interactions | 4734 | 281 | 57 | 16036 | 2547 |
CASP3,SCN5A,ANKRD13D,FAM189A2,CUL1,CAMK1D,TTYH3,SH3KBP1,TP73,WEE1,SCNN1A,IGF1R,TAF1B,PTEN,SIVA1,N4BP3,SMO,TMEM51,SGK1,ERBB3,RASGEF1A,SPRY2,SYK,EBAG9,PLK1,MAP3K3,AKT1,MAPKAPK3,RAPGEF2,PYM1,RNF11,LITAF,SLC11A2,YES1,CDC25C,CDK5R1,EGFR,GABARAPL1,FYN,CASP7,FGFR2,MAP2,STK26,PLK2,UBE2D2,ABCB1,DCUN1D1,ARRB1,ARRDC1,GRIN2D,YOD1,ANXA9,LRRK1,MAP3K5,GUCD1,NDFIP1,RPS6KA3 |
| 2.813e-02 | -3.57 | mantle_cell_lymphoma | COSMIC cancer mutations | mantle_cell_lymphoma | 2976 | 467 | 17775 | 2585 |
FAM171B,HECA,ACACB,GAA,PPP4R4,ATP8A1,TSC22D3,KLC2,TAP1,NRG2,PDGFRL,BAIAP3,CCNB1,DPP8,FAM46C,KIF26A,SLC35E4,CDKN2C,DAPK2,ZYX,ARHGAP42,TGFBR3,CTGF,KIAA1107,DNAH6,STIM1,IQCE,CABP1,PAQR5,SLC46A1,IL31RA,AOX1,STEAP2,PIK3CA,ATRNL1,MTMR11,TMEM37,TIAM1,CPE,ODF2L,XKR8,NEK4,SPEF2,HSPA12A,TMEM98,TNS1,LDB2,SPNS3,ABR,ARHGEF26,AHRR,MPRIP,WDR11,ANKRD6,ATP7B,CELF5,MYLK,LRIG1,FAM114A1,NOD2,PRDM5,RNASEL,RELL1,STARD13,GAB1,ANXA11,ZNF720,DLAT,DDX58,SCN5A,MRC2,FRMD4A,CDKN1C,TBC1D1,CALB2,MTL5,ZNRF3,SLC1A3,NOTCH2,MERTK,SH3RF2,RAVER2,DOPEY2,RALGPS2,FRY,ITGA3,FAM189A1,MEGF8,PRKG1,SORL1,CADPS2,STT3B,CACNA1D,PIKFYVE,MOXD1,KCTD3,ZNF117,RIMS2,MCCC2,DNAI1,TRAK2,PRODH,KCNJ12,KLK5,LPGAT1,MYBL2,WHSC1,CALCRL,KIF20B,ATP8B3,NPHP3,SFXN5,NFIB,DCP2,PDE11A,FAS,CACHD1,AP1AR,PLEKHH2,FAAH,ISM1,TCEAL4,MPP2,NDE1,MAP3K5,TRPC3,PKD1L2,DOCK9,MFSD3,PLEKHG3,GPR107,S100A11,IQGAP1,RALBP1,ETNK1,RNF182,MGST2,FLT3,DDR1,ART5,ZNF385B,CDS1,CCND1,MUC16,SCNN1A,MYT1,SCN3A,MYO5B,MX1,SEC23A,FOXJ2,DRAP1,SYNE2,UTRN,DNAJB14,PYGO1,CBL,ATP10D,GIGYF1,NIN,PRDM11,FYN,PDLIM3,JAK1,ACAD10,SHROOM3,WFS1,WWTR1,INPP4B,TRIOBP,ZNF704,NRG1,NR3C2,COBL,ARNT,MRPS9,FARP1,PLSCR4,TAOK2,FAM189A2,JRKL,SLC41A1,TRAF2,PDIA3,EFHD2,GPR180,SEPP1,PNPLA5,ICAM1,NEO1,WWP2,SLC25A36,SNTA1,ANK1,FUT2,OXCT1,ANKS1B,CTSC,PTEN,KNDC1,KCNK5,FAM20B,ATP8B1,SLC44A2,WWP1,MAP3K7,NCOA2,SMC4,RASGRF1,PDGFC,CASK,PLSCR1,FAM160A1,FMN1,RAPGEF2,MFSD2B,PIK3R1,CXorf57,AK4,DIAPH2,YES1,GRTP1,ARSK,ABLIM2,TXK,RPL12,MAMDC4,KIAA0141,PLOD2,RAB11FIP2,ZFP30,ABCB1,ARSB,USF2,CXorf56,OCLN,TLL2,EXPH5,LTBP1,LMCD1,VARS2,PLAC1,MPP5,ITPR2,CDIPT,PDGFB,DNER,KREMEN1,TMC1,DENND2D,PLS3,ARHGEF10L,ADPRHL1,NKAIN3,SIPA1L2,ENTPD4,CASC4,ARHGEF37,SHC3,NPNT,IMPAD1,SLC44A1,DDHD2,ANKFN1,DLG1,DUSP10,RP2,ARNT2,MYH14,ANO4,MYRIP,BTBD3,IL1RAP,RASGRP1,ZNF462,MCTP1,CELSR2,ASXL1,FOPNL,NFE2L1,RNF165,RGAG1,ANLN,IDH1,SESN1,PTGFRN,ZBTB7B,VCP,EDNRA,DPYSL3,MDK,MAN2A2,PLCH1,MFAP3L,NEIL1,GPRC5B,KLF12,MAP2,TDRD7,CTNND1,KLF11,EPB41L4A,GLCCI1,HS6ST3,PCSK5,PRKAA2,LASP1,USH1C,PPP1R12A,BVES,HLA-F,ELOVL7,ETV5,CNTNAP2,SAMD9,PHLPP1,IL18R1,ANO1,RB1,PFKL,FRAS1,SRP54,FNIP1,MDFIC,LIMCH1,PIM1,ALS2CL,SNED1,MDFI,CHSY3,WDR72,RGMB,PARD3B,PDE5A,HMG20B,EIF2AK1,KIAA1109,PRRC1,UNC45B,ANKRD29,AMDHD1,SOX13,RASGRP2,DHDH,INSR,UTP14C,ALPK3,NXPH4,CTSA,LTBP2,PLD1,SEMA3A,CDAN1,COL16A1,NIPA1,FAM45A,USP43,KLF7,NCKAP5,ZSWIM5,NF2,FOXM1,TMX4,SOD2,TP53,P2RX7,TDRKH,OSR2,MICALL2,STIL,CDK14,CYP4F11,TACC2,FRYL,N4BP3,GYS1,RPN2,STEAP3,EGLN3,ETHE1,F2R,MBP,ERBB2IP,TMTC2,DOCK5,TAPBP,RTN4RL1,BFSP1,PTK7,ADAMTS14,TLE1,MAOA,CHMP4B,RCAN2,SPTBN5,IRF7,EFNA5,CYP2U1,SYT13,NDST3,LIFR,KDELC2,FAM134B,CDS2,TRAPPC10,TSPAN15,POC1B,SCD5,GABRG2,SELL,COL4A5,JAG2,XPR1,PPP2R3A,ITGA2B,NRP2,CD109,FOXP2,IRF2BPL,MDM1,BMP7,GALNS,GTF2F2,ARVCF,ALDH7A1,CLIP2,TLE6,DLGAP1,HMMR,SUN2,FBLN5,RAB3B,AMFR,ASPM,RC3H2,OGDHL,MAML2,COL7A1,CAPNS1,PELI3,TXNDC11,BBS2,SPAG1,PRDX4,ARHGAP24,ENDOD1,SERPINA1,FAT4,FIBCD1,TMC5,CDCA7L,UBE2D2,PGRMC1,CLIP4,FAM117A,UACA,ARRB1,SH3BGRL2,PKD2,GRAMD1C,SOX8,ATP6V1C1,TBC1D4,HIPK3,ZBTB33,ARHGEF4,GOLGB1 |
| 2.813e-02 | -3.57 | cellular response to radiation | biological process | GO:0071478 | 153 | 32 | 16441 | 2455 |
CUL4B,SWI5,TP53,CALM3,BCL2L1,TP73,CALM2,PCNA,GNB5,DNM2,BAX,CRY2,CNGA1,RPGR,EEF1D,METAP2,SIRT1,DDB2,FIGNL1,PBK,CASP9,PIK3R1,CALM1,PRKCQ,AURKB,ELK1,NMT2,RHOB,KDM4D,PTGS2,RGS9,FNTA |
| 2.813e-02 | -3.57 | positive regulation of epithelial cell proliferation | biological process | GO:0050679 | 153 | 32 | 16441 | 2455 |
GRN,SCN5A,SOX9,ERBB2,TGFBR1,OSR2,EGR3,PDGFB,NRP2,BMP2,CCND1,CTNNB1,SMO,CDH3,TWIST1,MYDGF,IQGAP3,SIRT1,AKT1,NR4A1,FZD7,EGFR,ACVRL1,SCG2,FGFR2,TBX1,TBX18,NR4A3,NOD2,EGFL7,OSR1,ARNT |
| 2.818e-02 | -3.57 | GTAAGAT,MIR-200A | MSigDB lists | GTAAGAT,MIR-200A | 51 | 13 | 17758 | 2588 |
PCGF5,PAX6,SP100,NR4A1,SUZ12,SHPRH,FLRT3,AMMECR1,FURIN,KCNS3,SGK1,WHSC1,KLF9 |
| 2.818e-02 | -3.57 | HENDRICKS_SMARCA4_TARGETS_UP | MSigDB lists | HENDRICKS_SMARCA4_TARGETS_UP | 51 | 13 | 17758 | 2588 |
SMARCA2,FBLIM1,ITGA3,SERPINE2,CTSB,AIM1,ARL4C,FHL2,EMP3,LOXL2,S100A2,LMNA,MAP1B |
| 2.818e-02 | -3.57 | ZHU_CMV_8_HR_DN | MSigDB lists | ZHU_CMV_8_HR_DN | 51 | 13 | 17758 | 2588 |
TFAP4,WEE1,TGFBR3,IGF1R,NR3C1,SH3D19,IL6ST,TFAP2A,ACO1,IGFBP2,FBLN1,AHR,LMNA |
| 2.818e-02 | -3.57 | BERNARD_PPAPDC1B_TARGETS_DN | MSigDB lists | BERNARD_PPAPDC1B_TARGETS_DN | 51 | 13 | 17758 | 2588 |
ADD3,SERPINA1,MACC1,FGFR2,MAPKAPK3,KCNK5,IL6ST,SH3BGRL2,SYT13,FAR2,ZMIZ1,RAP1GAP,PRR7 |
| 2.818e-02 | -3.57 | MODULE_85 | MSigDB lists | MODULE_85 | 51 | 13 | 17758 | 2588 |
FGFR2,PTK7,AXL,EPHA4,RYK,ERBB2,IL13RA1,PDGFRL,TGFBR1,ROR1,EPHB4,MERTK,LEPR |
| 2.819e-02 | -3.57 | GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN | 180 | 36 | 17758 | 2588 |
NQO1,LFNG,HEBP1,CCM2,RNF182,RACGAP1,CKAP5,RB1,ZNRF2,MEGF8,FJX1,PRKCI,MTMR10,RP2,TRAM1,EBAG9,HN1L,TBC1D8B,VEZT,NUBP1,BORA,ATP10D,ANKRD29,DDX23,BCAR3,P4HA2,PTER,CDCA7L,ARAP1,GLB1,MRPS28,GLA,GEM,STARD13,ZNF701,ZBTB33 |
| 2.819e-02 | -3.57 | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP | 180 | 36 | 17758 | 2588 |
BIN1,GCAT,TSC22D3,KLC2,MCCC1,DGKA,DHX8,TRMT2B,PDGFB,RSAD1,TP73,TTC21B,ZNF75D,CES2,SLC44A1,ZDHHC13,FAM63A,IRF2,RFX5,CACNA1D,DLX4,PPP6R1,SCYL3,XKR8,CELSR2,MAPKAPK3,CORO2A,SYNE2,KLK6,SEC14L2,MAP3K11,ERAP1,ARRB1,PIK3C2B,IFIH1,ARNT |
| 2.823e-02 | -3.57 | regulation of lamellipodium organization | biological process | GO:1902743 | 35 | 10 | 16441 | 2455 |
SSH3,RAC2,SSH1,DMTN,ARHGEF7,CORO1C,DNM2,NCKAP1,ARPC2,CORO1B |
| 2.823e-02 | -3.57 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0031146 | 35 | 10 | 16441 | 2455 |
FBXL16,KIF14,WWTR1,FBXL14,FBXO2,FBXO9,CUL1,FBXO6,CCNF,FBXW5 |
| 2.824e-02 | -3.57 | NAD/diacylglycerol_kinase | interpro domains | IPR016064 | 17 | 6 | 18293 | 2672 |
NADK2,DGKH,DGKG,DGKQ,DGKE,DGKA |
| 2.824e-02 | -3.57 | Sulfatase | interpro domains | IPR000917 | 17 | 6 | 18293 | 2672 |
GNS,ARSB,ARSK,ARSG,GALNS,SULF2 |
| 2.835e-02 | -3.56 | filopodium | cellular component | GO:0030175 | 88 | 20 | 17570 | 2579 |
MTM1,FARP1,INPPL1,NF2,SYNE2,EPHA4,ARL4C,SPATA13,UTRN,UBE2Q1,EZR,ANTXR1,DAG1,LCP1,VASP,ITGA3,ACTA2,ITGAV,ARF6,MYO5A |
| 2.846e-02 | -3.56 | GSE17721_CTRL_VS_POLYIC_8H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_8H_BMDM_UP | 186 | 37 | 17758 | 2588 |
GCLM,BCAM,FAM134A,TESK2,MRAS,SEPP1,LTBP3,BCAP31,CCNA2,OPN3,ADAM15,TAX1BP3,APIP,TECR,MPHOSPH9,MED22,CERS2,SYPL1,MBP,ARHGDIB,RAD17,ANLN,SESN1,CYP4F3,VCP,TCN2,OSBPL2,NUCB1,RPL12,GDE1,TIMM8A,LIMK1,PRPS2,CTSA,MDH1,PDXK,CD81 |
| 2.846e-02 | -3.56 | MORF_RAB1A | MSigDB lists | MORF_RAB1A | 186 | 37 | 17758 | 2588 |
GAA,LASP1,SEC61G,ARFGEF1,MORF4L2,RAB6A,BCAP31,SLC25A36,CYHR1,DNPEP,P4HB,CDK16,PSMC2,TMBIM6,RPN2,TMED2,KDELR1,EBAG9,PIGC,LAMP2,SHMT1,SEC61B,PSMB4,VAMP3,UBE2A,NUBP1,POR,LEPR,MYL12A,ABR,ARF4,RHEB,MDH1,B4GALT3,MYL12B,PRKAR1A,RAD21 |
| 2.846e-02 | -3.56 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN | 186 | 37 | 17758 | 2588 |
C1orf198,FAM81A,FAM101B,DENND2D,DNAJB9,CALR,OTUD1,RNF220,ADORA1,PIK3AP1,FOSB,DUSP10,SGK1,NTN4,KLF9,PIM1,FAM84B,MYLIP,C9orf72,IGDCC4,CTH,ZNF462,ADAM17,RIPK2,DBR1,CASP4,IRS2,BANK1,LRIG1,INPP4B,NETO2,PGM2L1,FAM149A,NR4A2,PDXK,C17orf75,ST3GAL1 |
| 2.846e-02 | -3.56 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP | 186 | 37 | 17758 | 2588 |
BIN1,CHCHD7,TSC22D3,PPFIBP2,NRG2,ELF3,ENTPD4,CYP1A1,SP100,CYP4F11,DDHD2,ADCK2,ECE1,RAB27B,MAST4,SLC16A5,RASGRP1,EEF1D,XKR8,WBP5,DOCK4,ENPP4,ARAP2,PTPRU,LGALS8,CORO2A,SRSF5,STEAP1,CNTNAP1,BTG1,RCBTB2,COL13A1,NR1D2,KBTBD2,TBX1,PLXND1,L1CAM |
| 2.846e-02 | -3.56 | GSE3982_DC_VS_BASOPHIL_UP | MSigDB lists | GSE3982_DC_VS_BASOPHIL_UP | 186 | 37 | 17758 | 2588 |
GRN,GAA,NQO1,GALNT12,ADO,SLC1A3,NANS,NTAN1,SLC20A1,MERTK,SPSB1,PPP2R3A,PER2,ARHGEF10L,CCDC92,DRAM1,TIAM1,SPRY2,GM2A,MCCC2,SNED1,QSOX1,CDYL,MBNL3,DIAPH2,TNS1,ALCAM,CD83,SCARB2,MAOA,DYSF,CLIP4,GLB1,TMEM8B,NRGN,LTA4H,ACOT7 |
| 2.846e-02 | -3.56 | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP | 186 | 37 | 17758 | 2588 |
GLIS3,RUSC2,BLVRB,BAIAP3,TTYH3,SYTL2,FAM160A2,FOSB,DNM2,ANKRD12,FAM102A,CNGA1,TMEM8A,SLC16A5,PAQR7,SUSD3,TNIP1,USP18,COL7A1,TNFAIP8L1,ATP8B3,ITPR3,CD40,IFIT3,ATP10D,ABLIM2,BSDC1,GABRD,ZNF628,TBC1D17,COQ10A,ACAD10,RIN3,CMPK2,ARSB,TRAF5,ST3GAL1 |
| 2.846e-02 | -3.56 | GSE360_L_MAJOR_VS_T_GONDII_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_T_GONDII_DC_DN | 186 | 37 | 17758 | 2588 |
SLC25A24,CRYM,HABP4,C5orf30,COL4A5,MERTK,IL18R1,SLC9A7,FANCI,PDIA4,WWP2,B4GALNT1,DIRAS3,TAF1B,PHTF1,DIXDC1,CACNA1D,GFI1,KANK3,CPE,OLFML2A,TMCC2,POU6F1,SGCE,GCLC,KCTD2,RASGRP2,DGCR2,HOXA9,PEX2,MATN2,WWTR1,ERAP1,OSMR,GDF11,ST3GAL1,DRD1 |
| 2.846e-02 | -3.56 | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN | 186 | 37 | 17758 | 2588 |
PLA2G4A,SERPINE2,SEC61G,CCM2,XIAP,TXNDC9,COMMD5,LGALS3BP,CKAP5,DTX3L,ZFYVE16,FAM20C,ZNRF2,IL6ST,PHTF1,ALDH1A3,SLC30A6,AIM1,MDFIC,ARNT2,TRAM1,HSPA2,PARP9,C6orf1,STX3,PSMD3,ZMYND19,PPP2R4,DBI,NR4A3,GLA,ATP1B3,PLOD3,STARD13,CD81,LNP1,DLAT |
| 2.846e-02 | -3.56 | GSE27786_LIN_NEG_VS_BCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_BCELL_UP | 186 | 37 | 17758 | 2588 |
MTM1,SLC25A24,SERPINE2,ASB9,ERI2,NENF,MNS1,SLC25A35,ELF3,IL6ST,PRC1,ECI2,STEAP3,RPN2,PIK3CD,AK3,CITED4,PTPN9,MRS2,CCDC34,AK4,MRPS35,CCNF,BORA,SOX13,OPTN,DCAF10,AP1AR,ACADSB,RBL1,DBI,FAM149A,MLKL,ALG2,GLA,WDR62,TBC1D4 |
| 2.849e-02 | -3.56 | human chr1p36.22 | chromosome location | human chr1p36.22 | 35 | 8 | 26250 | 2805 |
CTNNBIP1,CLSTN1,FBXO2,FBXO44,FBXO6,SPSB1,RBP7,MIIP |
| 2.849e-02 | -3.56 | developmental process involved in reproduction | biological process | GO:0003006 | 602 | 107 | 16441 | 2455 |
ACVR1,GRHL2,LGR4,EPAS1,ST14,LFNG,HEXB,GATA3,PLAC1,BCL2L1,SEPT4,CCNB1,SDC1,PRKACA,PDGFB,NPM2,CCND1,RPS6KA2,CTNNB1,LRRC6,PAQR5,DLG1,PLK4,TIPARP,HSPA2,SIRT1,SMARCA2,SOD1,AKT1,FZD4,TFAP2C,PYGO1,CCNF,IDH1,SOCS3,PTGS2,HS6ST1,AREG,HOXA9,AXL,TDRD7,E2F8,GAB1,ARNT,COL9A3,NKX3-1,CDKN1C,SERPINE2,CENPI,CTSB,BIK,ETV5,SOX9,TGFBR1,MERTK,SIX4,ICAM1,SGPL1,IRF2BPL,SPP1,E2F7,DAZAP1,IGF1R,ITGB8,PTEN,CYR61,GATA2,TOX2,CST3,MSH2,UBE2J1,BAX,CITED2,TTPA,TMED2,MDFI,PAQR7,REC8,HES1,ASPM,DIAPH2,FNDC3A,BBS2,KDM3A,EGFR,PRDX4,PITX2,NCOA3,INSR,PVRL2,FGFR2,PRDX3,CSF1,CTSV,SPINT2,SERPINB5,ARRB1,PKD2,HOXB13,FZD5,OSR1,SOX8,HOOK1,AHR,RARG,FOXA1,EGLN1 |
| 2.852e-02 | -3.56 | CACNA1A (calcium channel, voltage-dependent, P/Q type, alpha 1A subunit) | protein interactions | 773 | 97 | 23 | 16036 | 2547 |
GRN,LTBP1,AGRN,HSPG2,CALM3,JAG2,FBLN1,CACNB4,TSPAN7,LTBP3,GNB2,CKAP5,CALM2,BTG3,ZCCHC17,NOXA1,CABP1,MEGF8,MATN2,ABCA2,BCL6,CYSRT1,PCSK5 |
| 2.852e-02 | -3.56 | PSMD7 (proteasome 26S subunit, non-ATPase 7) | protein interactions | 5713 | 97 | 23 | 16036 | 2547 |
UFD1L,SLC2A4,PSMB4,NR3C1,TRIM5,PSME2,RNF11,PSMD10,UBAC1,FBXO6,MCFD2,PSMA4,KTN1,RAD23A,RGPD5,PSMD1,PSMD3,PSMC2,CCDC74B,BRAT1,CENPE,PSMC1,PSMA5 |
| 2.852e-02 | -3.56 | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | MSigDB lists | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | 151 | 31 | 17758 | 2588 |
ARHGAP11A,ZWINT,DLGAP5,HJURP,SPC25,CKAP2,NDC80,C5orf30,KIF23,NUSAP1,KIF2C,PIF1,CCNB1,ANLN,CASP4,PSIP1,TOP2A,SLCO4A1,DAZAP1,CCNA2,UBE2T,H2AFY,XRCC3,KPNA2,KNTC1,CENPE,SPCS3,NCAPG2,ESPL1,FGFR1OP2,MELK |
| 2.852e-02 | -3.56 | NEGATIVE_REGULATION_OF_CELL_PROLIFERATION | MSigDB lists | NEGATIVE_REGULATION_OF_CELL_PROLIFERATION | 151 | 31 | 17758 | 2588 |
QSOX1,ING1,NF2,IGFBP6,CDKN1C,S100A11,CNOT8,EMP3,COL18A1,CUL1,RUNX3,FTH1,NOTCH2,TP53I11,PRKRA,ETS1,SESN1,CDKN2C,TSC1,BTG1,BTG3,PTEN,ACVRL1,SCG2,CGREF1,FABP6,KLF11,CDKN2D,CTBP1,TOB1,CD33 |
| 2.854e-02 | -3.56 | APP (amyloid beta (A4) precursor protein) | protein interactions | 351 | 2082 | 361 | 16036 | 2547 |
HSPG2,KLC2,PPFIBP2,PSME1,ISOC2,CAMK1D,DAPK2,PAK6,NAPG,OSTCP1,AP1M2,ANKS6,RGS3,ZFP36,POLL,DNM2,TUBG1,IRF2,APOBEC3G,ODF2L,METAP2,UXT,RNF11,NBPF3,AGO4,AURKB,SLC17A5,F12,MCFD2,ZFAND5,PNKD,RAB2B,ABR,TRIM47,AREG,GNPTAB,LIMK1,PLK2,PPP2R4,TRAF3IP1,MAP3K11,AGFG2,MAPK13,TMOD2,ARF6,E2F8,NXT2,ZNF720,CDK17,NUAK1,GGA1,ITGA6,C6orf106,NDUFA4,APBA1,MESDC2,SH3RF2,CALR,ZCCHC17,ATP5H,NECAB3,BDH1,SORL1,SLAIN2,OSTF1,PIKFYVE,CTSD,MAPK7,C9orf72,EEF1D,SOCS5,EPB41L5,NUDT16P1,KIAA1841,PRSS23,MAPKAPK3,PYM1,PIP4K2C,FHL2,WHSC1,FAM133B,PKM,MEST,ELK1,RASA1,C11orf45,NAAA,FAM64A,MTFMT,CSNK1G1,SETD3,ARAP1,AURKA,KLK7,CDK18,PLIN3,IFIH1,RUSC1,ARMCX3,PAPSS2,GRHL2,DLGAP5,LFNG,GALNT12,FAM131C,ZNF385B,EPS8L2,APPBP2,EPHB4,PDE4D,ACSL4,ARL4D,FLOT2,ETV4,ZNF365,CDKN2D,MED30,NAGA,TMCC2,MX1,SSH3,PSRC1,DMTN,FOXJ2,DRAP1,CLSTN1,NUSAP1,DNAJB14,RAB38,C15orf39,H2AFV,ZNF641,CCNB3,ACYP1,STK26,CCDC149,ACAD10,RGS14,PRR15,GALK1,ANKRD13D,PLEKHJ1,CENPI,DCAF7,BACE1,BIK,ARL4C,CDCA3,FLOT1,PDIA3,EFHD2,APOBEC3H,TMA16,ARHGEF40,ETS1,TIPRL,RASSF8,CXCL16,PHF7,GNB5,PPP1R10,ANKS1B,KCNK5,DRAM1,SGK3,ECI2,MAPK11,TAGLN2,RAG1,TTPA,TGIF1,ZWINT,ALDH2,PLSCR1,VAMP3,AK4,UBAC1,LRRC1,FOS,DCTN6,RPL12,LDLRAP1,HCP5,FGFR2,ATXN7L3,CSTF2,ARFGAP3,HMGA1,WDR45B,SRSF9,CXorf56,DEF6,CASP3,SIGIRR,NMRK1,CAMKK1,CUL4B,LMCD1,TEX2,KIF2C,CDIPT,SDC1,NUP62CL,ECI1,FANCI,PLS3,ZFYVE16,CTNNB1,ZCCHC12,CASC4,SHC3,SIVA1,DDHD2,MITF,RGS5,ARNT2,TRAM1,OLFML2A,PLK1,LAP3,ASXL1,STRIP2,C12orf65,TNFAIP8L1,ARHGDIB,MRPS18A,ROR1,FAM212B,STK17B,TRUB1,TCN2,DZIP1L,LRRC42,CXXC4,NEIL1,KLF12,MAP2,IARS2,ARRDC1,CTNND1,KPNA2,EPB41L4A,APBA2,PSMC1,RMND5A,LGALS3,ETV5,FBLN1,IGF1R,PFKL,PAK2,TBCD,FCHO1,WASH2P,PRKCI,EBF4,LIMCH1,RFX5,PIM1,PSMA5,HP1BP3,ELK3,HMG20B,PDK3,PRRC1,IFIT3,BCL2L13,RANBP9,CDK5R1,EGFR,NMT2,RASGRP2,BCAR3,ZC2HC1A,H1F0,TMEM30A,PLPP3,ZDHHC7,FAM213A,IFI6,TOB1,KLF7,CCNE2,FAM214B,AVPI1,KCNAB3,HOXB7,IL15,PSME2,SOD2,RASGRP3,CCNL1,PHLDA1,PCBP1,BCAP31,SDF4,MXD1,C1orf116,IER3,SRR,ZDHHC23,GYS1,DIXDC1,ETHE1,LMAN1,HSPA2,UPF3A,SUSD3,AKT1,CDC20,ACO1,DUSP4,CASP4,C3orf33,SOCS3,IDE,BHLHB9,PEX2,PTBP3,ANXA9,AIFM3,POMGNT2,ZC3HC1,FAM134B,BIN1,CMAS,CTSB,MCTP2,ARMC7,COL4A5,CHAC2,TRIB2,MZT2A,TAF1B,CDK16,TOX2,H2AFY,MTURN,TSPAN13,ALDH7A1,SYK,PGM1,PHF20L1,PSMB4,CRIP2,PELI3,FNDC3A,POLD3,TCEAL8,MAPK8IP1,USP6,ARHGAP24,FUCA1,SMTNL2,TRIM69,SPINT2,CLIP4,OTUB2,GRAMD1C,GUCD1,NXPE3 |
| 2.858e-02 | -3.55 | TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS | MSigDB lists | TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS | 111 | 24 | 17758 | 2588 |
SIRT1,UGT8,XYLT1,MGAT4B,PYGL,GALNT7,POMGNT1,B4GALT4,ITGA2B,B4GALNT1,GALNT3,B3GALNT1,TYMP,FUT2,A4GALT,MGAT4A,FUT8,CSGALNACT1,FUT1,ALG2,STT3B,B4GALT3,ST3GAL1,GCNT1 |
| 2.859e-02 | -3.55 | lung development | biological process | GO:0030324 | 176 | 36 | 16441 | 2455 |
KLF2,GRHL2,EPAS1,TMTC3,THRA,MAN1A2,SOX9,CTSZ,GPSM2,PDGFA,TNS3,ITGA3,CTNNB1,CTGF,GPC3,TMBIM6,PDE4D,PPP1CA,SPRY2,THRB,ADAMTS2,HES1,ASXL1,RC3H2,SAV1,NPHP3,DAG1,NFIB,CRISPLD2,HS6ST1,FGFR2,PTK7,FGF18,PLOD3,LTA4H,FOXA1 |
| 2.865e-02 | -3.55 | human chr1p31 | chromosome location | human chr1p31 | 17 | 5 | 26250 | 2805 |
DIRAS3,PRKAA2,PGM1,ACADM,LEPR |
| 2.870e-02 | -3.55 | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP | MSigDB lists | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP | 192 | 38 | 17758 | 2588 |
GSDMD,TXN,TMEM184B,TRAF2,TXNDC9,HMGN3,SNN,SPSB1,ICAM1,CCND1,ZYX,PDCD10,FAM46A,PIK3AP1,ARHGEF37,ZFP36,RAB20,ARMCX6,XKR8,PVRL4,ENPP4,ADAM17,TMEM68,PAPD7,SAT1,DBR1,RNPEP,BCL10,SOCS3,FRMD4B,PTGS2,CCDC6,PLK2,HDAC1,MLKL,HMGA1,FOXA1,JARID2 |
| 2.870e-02 | -3.55 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | 192 | 38 | 17758 | 2588 |
GALK1,IL15,SLC25A13,SERPINB9,ERCC6L,LYNX1,HERC6,KBTBD11,CALR,NOV,CCNA2,ELMO2,OSBPL3,NEK2,GTF2F2,ECE1,LMAN1,TIAM1,SLC16A5,PSMA5,KDELR1,MRPS33,PSMB4,IFITM3,SH3BGRL,CKAP2L,CDCA2,NPC2,RNF19B,PSMA4,PRDX4,TAPBP,CASP7,RBL1,PEX2,NMI,MRPS28,E2F8 |
| 2.870e-02 | -3.55 | GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDM_UP | 192 | 38 | 17758 | 2588 |
COL9A3,GNPDA1,RHBDL3,MTL5,OAT,ZNF219,SLC20A1,RBP7,CHPF,TMEM63A,WDFY1,RPS6KA2,DPYSL2,MAGEE1,MKRN3,TNPO2,TRPC1,BUB1,STT3B,PIM1,DDX59,BAG4,FOPNL,RC3H2,CBX6,PTGER4,COL7A1,DOCK5,SOX13,ARHGAP35,C19orf66,NFKBIA,NR4A3,CHMP4B,TMOD2,ATP6V1C1,TMEM131,JARID2 |
| 2.870e-02 | -3.55 | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 192 | 38 | 17758 | 2588 |
SUN1,RMND5A,HECA,PACSIN2,ST13,MRPS15,PBX3,ASAH1,KCTD12,NKRF,PJA2,LBR,PAK2,SORL1,RPN2,USP1,MAP3K7,SLC35A1,NR2C1,MAP3K3,TRIM8,DSTN,FOXJ2,FBXO9,RNF113A,ESYT1,KDM3A,ZDHHC3,DCP2,LCP1,RASA1,AMZ2,CARHSP1,LDLRAP1,ZDHHC7,SPCS3,RPL22,LSM14B |
| 2.870e-02 | -3.55 | GSE3982_DC_VS_MAC_LPS_STIM_DN | MSigDB lists | GSE3982_DC_VS_MAC_LPS_STIM_DN | 192 | 38 | 17758 | 2588 |
DDX58,PAPSS2,DLGAP5,P2RX7,NDUFA4,DUSP5,TSPAN7,SYTL2,RND1,PLS3,CAPN2,APOBEC3B,SPP1,ZFX,KCTD15,TGFBR3,FAM46A,P4HB,OCRL,RRBP1,PRC1,RAB27B,CPE,THRB,MARK1,ZWINT,B3GNT2,CDC20,KCTD20,EZR,CAPNS1,IFIT3,RNF19B,SLCO4A1,NEIL1,HPSE,DTX4,LTA4H |
| 2.870e-02 | -3.55 | GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN | 192 | 38 | 17758 | 2588 |
INPPL1,GOLIM4,CERCAM,RUSC2,GDF15,GMCL1,CCNL1,STIL,PHLDA1,TNFSF9,M6PR,IER3,ZFP36,SGK1,FAM102A,SLAIN2,PIM1,CPE,SCN3A,PARP9,DUSP1,GFPT1,ATL1,BAG4,FBLN5,TMEM68,BCL9,USP18,IGSF8,ANLN,FOS,SOCS3,TRIM47,PHLPP2,NFKBIA,NFKBIZ,NUP37,TRAF5 |
| 2.870e-02 | -3.55 | GSE17721_LPS_VS_CPG_16H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_CPG_16H_BMDM_DN | 192 | 38 | 17758 | 2588 |
LGALS3,FAM129B,KCTD12,CNTNAP2,CENPN,SLC9A3R2,LMNA,ADD3,NUP210,IL31RA,NEK2,SLAIN2,ALDH7A1,LGMN,TFG,ABCC1,PLK1,SYPL1,SLC5A11,KIF20A,SEPT6,PBK,FHL2,UBE2A,PRICKLE1,PYGL,SCRIB,TP53INP2,ULK2,TRAM2,MSL1,COQ10A,UEVLD,RCBTB2,TIMM8A,EGFL7,NCAPG2,RPS6KA3 |
| 2.870e-02 | -3.55 | GSE17721_CTRL_VS_POLYIC_12H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_12H_BMDM_DN | 192 | 38 | 17758 | 2588 |
IQGAP1,RHPN2,DNAJB11,NDRG2,CCNL1,TNFSF9,APPBP2,IGF1R,TIMP1,PIK3AP1,MAPK11,ARNT2,PIM1,CTTN,IL10RB,GCA,RIPK2,MFI2,SYNE2,CYS1,SPA17,PRICKLE1,RAB38,CYFIP2,SPTLC2,CLCN2,PSMA4,EGFR,ARF4,CD83,PGF,GDE1,PVRL2,WFS1,HDAC1,HMGA1,FZD5,PPP2R2D |
| 2.870e-02 | -3.55 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 38 | 17758 | 2588 |
ADD1,RPS6KA1,ADO,NDRG2,BCL2L1,CRABP2,CDIPT,SDC1,PHF1,TEAD3,ITGA3,IGF1R,ARTN,KIF13B,PLCG2,VAT1,LGMN,SMYD5,ALDH3A2,EEF1D,UPF3A,MX1,P2RX4,PCCB,CENPA,TACC1,CDA,CLSTN1,EMP3,RHEB,CD83,BCAR3,KLF12,GLB1,FAM149A,SERPINB6,PLOD3,LTA4H |
| 2.873e-02 | -3.55 | REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING | MSigDB lists | REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING | 31 | 9 | 17758 | 2588 |
CALM2,GNB5,GRIK2,CALM1,DLG1,CALM3,DLG3,PLCB2,GNB2 |
| 2.873e-02 | -3.55 | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | MSigDB lists | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | 31 | 9 | 17758 | 2588 |
CCND1,JAK1,IGF1R,TACC1,CALD1,ITGA6,CDH3,EGFR,PRKAR1A |
| 2.873e-02 | -3.55 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | MSigDB lists | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 31 | 9 | 17758 | 2588 |
RAC2,FYN,RHOA,AKT1,PLCG2,PIK3R1,PIK3CA,SYK,RHOB |
| 2.873e-02 | -3.55 | BIOCARTA_MYOSIN_PATHWAY | MSigDB lists | BIOCARTA_MYOSIN_PATHWAY | 31 | 9 | 17758 | 2588 |
ARHGEF19,ARHGEF3,ARHGEF11,ARHGEF7,MYLK,PKN1,ARHGEF9,ARHGEF16,ARHGEF4 |
| 2.873e-02 | -3.55 | RIZ_ERYTHROID_DIFFERENTIATION_HEMGN | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION_HEMGN | 31 | 9 | 17758 | 2588 |
PITX2,NFE2L3,RB1,FOSB,PBX3,KLF5,NR4A2,E2F8,FOXA1 |
| 2.873e-02 | -3.55 | HOWLIN_CITED1_TARGETS_1_UP | MSigDB lists | HOWLIN_CITED1_TARGETS_1_UP | 31 | 9 | 17758 | 2588 |
KIF5B,CD8A,MBP,JAK1,KCNK1,GPC3,HAL,AIF1L,CBX5 |
| 2.873e-02 | -3.55 | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | MSigDB lists | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | 31 | 9 | 17758 | 2588 |
RHOA,SEC61B,TIMP1,NR4A1,CD82,SAT1,FURIN,GSTP1,ESYT2 |
| 2.880e-02 | -3.55 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032436 | 76 | 18 | 16441 | 2455 |
PLK1,DLGAP5,AKT1,DNAJB2,GCLC,NUB1,PRICKLE1,PSMD10,TRIB2,RNF19B,BCAP31,VCP,RB1,PTEN,PLK2,AURKA,ESPL1,SOCS5 |
| 2.885e-02 | -3.55 | Vibrio cholerae infection | KEGG pathways | ko05110 | 53 | 14 | 6908 | 1076 |
GNAS,ATP6V0B,PLCG1,SEC61B,SEC61G,PLCG2,ERO1A,KDELR3,ATP6V1E2,ATP6V1C1,SLC12A2,PRKACA,KDELR1,PDIA4 |
| 2.885e-02 | -3.55 | Vibrio cholerae infection | KEGG pathways | hsa05110 | 53 | 14 | 6908 | 1076 |
GNAS,ATP6V0B,PLCG1,SEC61B,SEC61G,PLCG2,ERO1A,KDELR3,ATP6V1E2,ATP6V1C1,SLC12A2,PRKACA,KDELR1,PDIA4 |
| 2.885e-02 | -3.55 | CAGTGTT,MIR-141,MIR-200A | MSigDB lists | CAGTGTT,MIR-141,MIR-200A | 300 | 56 | 17758 | 2588 |
CCNE2,RMND5A,CDK17,FRMD4A,FRMD6,ZCCHC24,BACE1,PHLPP1,BAHD1,SLC20A1,FAM46C,NRP2,IRF2BPL,SIPA1L2,TNS3,MDM1,WDR44,LHX6,STEAP2,DIXDC1,FAM84B,TRAM1,MYRIP,STK35,CPD,SIRT1,CYP26B1,THRB,ATL1,ASXL1,STAT4,AK4,TFAP2C,WHSC1,KIF1C,ATP1B1,RAB38,CBL,SP4,PITX2,IRS2,TSC1,HLF,RTN4RL1,PEX5,FGFR2,DOLPP1,PHLPP2,C1orf21,RAP2C,AGFG2,DMWD,FOXA1,ACOT7,HOXC13,NR2C2 |
| 2.886e-02 | -3.55 | MELLMAN_TUT1_TARGETS_DN | MSigDB lists | MELLMAN_TUT1_TARGETS_DN | 46 | 12 | 17758 | 2588 |
CCNE2,ALDH2,KLF12,NQO1,ALDH1A3,KLF5,KLF9,PACSIN1,SCARA3,SNX10,TXNDC11,KLF7 |
| 2.886e-02 | -3.55 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | MSigDB lists | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | 46 | 12 | 17758 | 2588 |
PSMD1,MRC2,PSMB4,PSME2,PSMD3,PSMC2,PSMD7,PSMD10,PSME1,PSMC1,PSMA4,PSMA5 |
| 2.886e-02 | -3.55 | ZHAN_MULTIPLE_MYELOMA_MS_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MS_UP | 46 | 12 | 17758 | 2588 |
MARK1,SERPINE2,NGFRAP1,KLHL13,MITF,CST3,RUNDC3B,PPM1H,WHSC1,MYRIP,SPRY2,PCSK5 |
| 2.886e-02 | -3.55 | SESTO_RESPONSE_TO_UV_C5 | MSigDB lists | SESTO_RESPONSE_TO_UV_C5 | 46 | 12 | 17758 | 2588 |
HES1,IQGAP1,PPP4R1,SDC4,STAT1,PBX3,WWP1,YES1,TIAM1,RASA1,ABCC1,CKAP5 |
| 2.886e-02 | -3.55 | PID_LKB1_PATHWAY | MSigDB lists | PID_LKB1_PATHWAY | 46 | 12 | 17758 | 2588 |
PRKAA2,CRTC2,TSC1,MAP2,PRKAA1,TP53,STRADB,CAB39,EZR,CTSD,ETV4,PRKACA |
| 2.886e-02 | -3.55 | PID_SYNDECAN_1_PATHWAY | MSigDB lists | PID_SYNDECAN_1_PATHWAY | 46 | 12 | 17758 | 2588 |
COL9A3,CASK,COL6A2,HPSE,COL13A1,COL6A1,COL7A1,COL4A5,SDC1,PRKACA,COL16A1,COL12A1 |
| 2.886e-02 | -3.55 | PHOSPHOLIPID_BINDING | MSigDB lists | PHOSPHOLIPID_BINDING | 46 | 12 | 17758 | 2588 |
ZFYVE16,ARAP2,WDFY1,MCTP1,ARAP3,MCTP2,PLA2G15,ARAP1,PRKCI,ANXA9,SYTL4,CCDC88A |
| 2.886e-02 | -3.55 | JNK_CASCADE | MSigDB lists | JNK_CASCADE | 46 | 12 | 17758 | 2588 |
TAOK2,SH2D3C,MAP3K11,KIAA1804,MAP3K9,DUSP10,MDFIC,MAP3K5,PKN1,MAP3K6,MAPK8IP1,MDFI |
| 2.887e-02 | -3.54 | regulation of toll-like receptor signaling pathway | biological process | GO:0034121 | 40 | 11 | 16441 | 2455 |
WDFY1,LGR4,PIK3AP1,FLOT1,NOD2,DAB2IP,IRF7,GFI1,F2RL1,FLOT2,IRF1 |
| 2.887e-02 | -3.54 | positive regulation of kidney development | biological process | GO:0090184 | 40 | 11 | 16441 | 2455 |
PDGFA,PROM1,HOXB7,LGR4,SOX9,RET,SMO,GATA3,SOX8,PDGFB,SIX4 |
| 2.887e-02 | -3.54 | peptidyl-tyrosine autophosphorylation | biological process | GO:0038083 | 40 | 11 | 16441 | 2455 |
TNK1,FYN,INSR,JAK1,IGF1R,YES1,TEC,JAK3,DDR1,SYK,TXK |
| 2.888e-02 | -3.54 | BROWNE_HCMV_INFECTION_48HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_48HR_DN | 485 | 86 | 17758 | 2588 |
MYL9,LMO7,ACACB,KIAA1462,ADD1,HSPG2,EPAS1,CNOT8,XYLT1,ATP2C2,PDIA5,ERBB2,PDGFRL,VASH1,SDC1,SPTB,PER2,CCND1,ZYX,ST5,TSPAN6,ZFP36,AOX1,GLB1L2,MTMR11,S100A13,OLFML2A,COL6A2,TEP1,LOXL2,PKMYT1,RNF19B,SOCS3,ENPP1,WIPI1,MAP2,STAT1,RCAN2,ITPKA,MAN2B2,GOLIM4,IGFBP6,ALDH6A1,ARHGEF11,PRKAA1,CRABP2,SEPP1,LGALS3BP,PPP2R3A,CALR,SPP1,ANK1,ITGA3,TBCD,COL6A1,MAPK11,MDFIC,MOXD1,SLC16A5,SNED1,DUSP1,FARP2,DLGAP1,PIGC,FADS2,ADAMTS2,FBLN5,PCDH1,RAB3B,PLAUR,BTN3A2,EMP3,CAPNS1,EIF2AK1,ZSCAN12,NFIB,MAP1B,STK17A,RASGRP2,MATN2,C1orf21,OSMR,LTBP2,GDF11,COL16A1,CSRP2 |
| 2.890e-02 | -3.54 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | MSigDB lists | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | 67 | 16 | 17758 | 2588 |
SLC2A4,INPPL1,AKT1,RPS6KA1,BCL2L1,PAK6,IRS2,TSC1,RPS6KA2,PTEN,PAK2,PIK3CA,CDKN1B,PIK3CD,GAB1,RPS6KA3 |
| 2.890e-02 | -3.54 | interaction with host | biological process | GO:0051701 | 159 | 33 | 16441 | 2455 |
LAMP1,CTSB,SERPINB9,TAP1,F11R,BCL2L1,ICAM1,XPR1,WWP2,CD46,NUP210,ADRBK1,SIVA1,WWP1,IFIT1,NCAM1,NUP85,PVRL4,CD55,TNIP1,ITCH,CR2,DAG1,SCARB2,IDE,INSR,PVRL2,AXL,KPNA2,ITGAV,NUP37,CD81,NUP58 |
| 2.897e-02 | -3.54 | LIU_SOX4_TARGETS_DN | MSigDB lists | LIU_SOX4_TARGETS_DN | 294 | 55 | 17758 | 2588 |
GRN,GAA,NKX3-1,DYRK3,IL15RA,TSC22D3,CUL4B,RASSF7,AKAP17A,SORBS3,PKN1,STIL,PRRG4,SSX2IP,ZDHHC21,APLP2,BTG3,KCTD15,SCNN1A,PFKL,CDK16,SIVA1,ELF5,SLC44A1,DLG1,FBXL14,UBE2J1,FLOT2,TMED2,TMX1,MSH6,P2RX4,ENPP4,SYPL1,SMARCA2,MFI2,MGAT4B,RC3H2,VAMP3,SRSF5,ITPR3,SGPP1,NFIX,FECH,PRDX3,SHROOM3,DBI,RAB31,HOXB13,HMGA1,RGS14,HIPK3,FOXA1,DLAT,EGLN1 |
| 2.897e-02 | -3.54 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN | 294 | 55 | 17758 | 2588 |
RECQL,PNISR,TRAPPC10,PPP1R12A,HABP4,CACNA2D2,C6orf106,PJA2,IL18R1,DUSP5,SYTL2,SCML1,CAPN2,CDKN2C,TGFBR3,HSF2,ENTPD4,KHNYN,GNB5,SLC16A6,AIM1,ANKRD12,TRPC1,F2R,GFI1,SGCB,TIAM1,TIPARP,NR2C1,SEC23A,CDKN2AIP,DDB2,MBP,B3GNT2,LGALS8,STAT4,PIK3R1,SRSF5,ALCAM,CASP4,FAS,OPTN,STK17A,KLHL2,CD8A,FYN,RCBTB2,RAP2C,ABCB1,FHL1,MAP3K5,TBC1D4,NR3C2,USP16,DLAT |
| 2.899e-02 | -3.54 | FASLG (Fas ligand (TNF superfamily, member 6)) | protein interactions | 356 | 92 | 22 | 16036 | 2547 |
DOCK4,PACSIN2,RHOA,MOSPD2,MACC1,PIK3R1,RGS20,EZR,SORBS3,EIF2AK1,TEC,YES1,EGR3,SNX9,CACNB4,FAS,SH3RF2,FYN,TJP3,SNX18,PIK3CA,OSTF1 |
| 2.899e-02 | -3.54 | BIRC3 (baculoviral IAP repeat containing 3) | protein interactions | 330 | 92 | 22 | 16036 | 2547 |
CASP3,RIPK2,TRAF2,DCAF7,CASP9,XIAP,CD40,SEPT4,CYFIP2,EGFR,BCL10,TP73,CASP7,UBE2Q2,FBXO7,UBE2D2,E2F1,UBE2J1,NOD2,DAB2IP,IRF1,SNX7 |
| 2.899e-02 | -3.54 | APPBP2 (amyloid beta precursor protein (cytoplasmic tail) binding protein 2) | protein interactions | 10513 | 92 | 22 | 16036 | 2547 |
MFSD3,PRKAA2,TCF25,LONRF3,FAM92A1,TCEB2,PYROXD2,ERO1A,CALM3,CCNL1,GSTP1,APPBP2,GALNT3,ANKRD10,RNF128,ZCCHC12,CDK16,DHRS2,AHCY,KLF11,AK3,PCSK5 |
| 2.899e-02 | -3.54 | PTPN12 (protein tyrosine phosphatase, non-receptor type 12) | protein interactions | 5782 | 52 | 14 | 16036 | 2547 |
TRIM47,TNS3,INSR,PACSIN2,DNPEP,UGP2,PLOD2,VASN,UTRN,NUSAP1,PRKACA,FLT3,BCAR1,EGFR |
| 2.900e-02 | -3.54 | GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN | MSigDB lists | GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN | 157 | 32 | 17758 | 2588 |
HSP90B1,CEP70,DLGAP5,FOXM1,NUF2,CHAC2,CCNB1,TMEM19,ADAMTSL4,PARM1,CABP1,BHLHE41,KIF14,PHTF1,TUBG1,ANO4,ITM2C,HMMR,SEC61B,ZWINT,KIF20A,PBK,TEF,STEAP1,CDK1,TRAM2,AURKA,B4GALT3,CCNB2,SHROOM2,E2F8,DENND5B |
| 2.901e-02 | -3.54 | PPP2CA (protein phosphatase 2, catalytic subunit, alpha isozyme) | protein interactions | 5515 | 204 | 43 | 16036 | 2547 |
GRN,PRKAA1,STRN4,TP53,CUL1,ISYNA1,TIPRL,PPP2R3A,CDKN2C,PSMD1,PDCD10,IRAK1,PPME1,ZFP36,TBCD,DAPK1,SGK1,TWIST1,PIM1,PPP1CA,GAD1,SPRY2,FGFR1OP2,MOB4,MAP3K3,SOD1,AKT1,SERTAD4,AURKB,VCP,RHOB,ZNF114,PPP2R5A,STK26,HTT,PSMD3,PPP2R4,UNC5B,SGOL1,CBX5,PPP2R5D,ESPL1,PPP2R2D |
| 2.902e-02 | -3.54 | Viral myocarditis | KEGG pathways | hsa05416 | 58 | 15 | 6908 | 1076 |
CCND1,HLA-B,CASP3,RAC2,CD55,FYN,HLA-F,HLA-E,CASP9,HLA-C,CD40,SGCB,DAG1,ICAM1,HLA-A |
| 2.916e-02 | -3.54 | CALM1 (calmodulin 1 (phosphorylase kinase, delta)) | protein interactions | 801 | 276 | 56 | 16036 | 2547 |
LMO7,SCN5A,GCLM,ADD1,CAMKK1,IQGAP1,ARHGEF7,ITGA6,CUL4B,STRN4,CUL1,DOCK11,GRM5,SNTA1,CCND1,SPP1,CCNA2,RALB,CALD1,KCNN4,DAPK1,DLG3,SYK,NEB,CAMK2G,ATP2B1,METAP2,HMMR,RAB3B,AKT1,NR3C1,SYNE2,CALM1,GRIN1,FBXO9,AURKB,SRSF5,CBL,EGFR,OPTN,FAS,GNAS,NT5C2,DDAH1,INSR,STK38,ITPR1,MYLK,DCUN1D1,CABIN1,ACADM,RPL22,ITPKA,TRPC3,NRGN,USP16 |
| 2.920e-02 | -3.53 | SNAI2 (snail family zinc finger 2) | protein interactions | 6591 | 20 | 7 | 16036 | 2547 |
HDAC1,PSMD1,PSMC1,PPP2R2D,PSMD3,SAT1,TP53 |
| 2.920e-02 | -3.53 | NCDN (neurochondrin) | protein interactions | 23154 | 20 | 7 | 16036 | 2547 |
AES,PPP1R2,PRCP,GINS4,EGFR,VCP,ASL |
| 2.920e-02 | -3.53 | SLC9A1 (solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1) | protein interactions | 6548 | 20 | 7 | 16036 | 2547 |
ARRB1,CA2,FAM189A2,LYPD3,CALM1,CHP1,MDFI |
| 2.920e-02 | -3.53 | ARID4B (AT rich interactive domain 4B (RBP1-like)) | protein interactions | 51742 | 20 | 7 | 16036 | 2547 |
SAP130,HDAC1,SIRT1,ETS1,CUL4B,MXD1,SUDS3 |
| 2.920e-02 | -3.53 | CAV3 (caveolin 3) | protein interactions | 859 | 20 | 7 | 16036 | 2547 |
DYSF,GNAS,SCN5A,INSR,PCBP1,DAG1,EGFR |
| 2.920e-02 | -3.53 | CASP8AP2 (caspase 8 associated protein 2) | protein interactions | 9994 | 20 | 7 | 16036 | 2547 |
TRIM21,MX1,BCL2L1,SP100,TRAF2,CALM1,FAS |
| 2.920e-02 | -3.53 | RNF123 (ring finger protein 123) | protein interactions | 63891 | 20 | 7 | 16036 | 2547 |
CDKN1B,ALDH3B1,UBAC1,PLOD2,BVES,C3orf58,RAD21 |
| 2.920e-02 | -3.53 | RNF34 (ring finger protein 34, E3 ubiquitin protein ligase) | protein interactions | 80196 | 20 | 7 | 16036 | 2547 |
PHF7,APPBP2,SH3KBP1,CASP9,CDC20,UBE2D2,TP53 |
| 2.920e-02 | -3.53 | KCNIP3 (Kv channel interacting protein 3, calsenilin) | protein interactions | 30818 | 20 | 7 | 16036 | 2547 |
CALM2,CASP3,KCNIP3,GRK6,IGF1R,ADRBK1,IL6ST |
| 2.920e-02 | -3.53 | SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2) | protein interactions | 6655 | 20 | 7 | 16036 | 2547 |
BIN1,PLCG1,LRRK1,SNX9,SNX18,SH3D19,EGFR |
| 2.920e-02 | -3.53 | GOLPH3 (golgi phosphoprotein 3 (coat-protein)) | protein interactions | 64083 | 20 | 7 | 16036 | 2547 |
RASSF8,PNKD,TIPRL,C3orf58,FAM20B,RANBP1,DCUN1D1 |
| 2.920e-02 | -3.53 | MICA (MHC class I polypeptide-related sequence A) | protein interactions | 100507436 | 20 | 7 | 16036 | 2547 |
TNPO2,GGH,ERLEC1,PHF7,TNFSF9,VAMP3,RYK |
| 2.920e-02 | -3.53 | CYHR1 (cysteine/histidine-rich 1) | protein interactions | 50626 | 20 | 7 | 16036 | 2547 |
EPN3,LGALS3,DNM1L,DNAJB2,NMI,VPS26A,H1FX |
| 2.921e-02 | -3.53 | regulation of actin filament-based process | biological process | GO:0032970 | 317 | 60 | 16441 | 2455 |
SCN5A,NF2,SSH1,ADD1,FRMD6,EPS8,SDC4,ARFGEF1,PKP2,SORBS3,F11R,NCKAP1,SPTB,ICAM1,PICK1,CORO1B,SNTA1,PDGFA,VASP,CTGF,CAPG,DLG1,DIXDC1,TACSTD2,PDE4D,CTTN,NEB,CCDC88A,SSH3,RHOA,BAG4,FMN1,DMTN,DSTN,PIK3R1,PTGER4,RGCC,EZR,PRKCQ,EPHA1,ILK,CDK5R1,RASA1,TSC1,AP1AR,SWAP70,PLEKHH2,ATP1A1,ARHGEF19,LIMK1,CTSV,TRIOBP,ARAP1,EFNA5,SPTBN5,TMOD2,ARPC2,ARF6,SHROOM2,F2RL1 |
| 2.924e-02 | -3.53 | MEMBRANE_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | MEMBRANE_ORGANIZATION_AND_BIOGENESIS | 134 | 28 | 17758 | 2588 |
SUN2,GCA,SOD1,PLSCR1,AGRN,TP53,VAMP3,VPS4B,BCL2L1,CBL,EGFR,PICK1,M6PR,ZFYVE16,NAPG,LDLRAP1,ADORA1,DNM1L,GATA2,A4GALT,CORO1C,REEP1,SH3BP4,CD9,STEAP2,SORL1,ARF6,CCDC88A |
| 2.926e-02 | -3.53 | RATTENBACHER_BOUND_BY_CELF1 | MSigDB lists | RATTENBACHER_BOUND_BY_CELF1 | 386 | 70 | 17758 | 2588 |
TNK1,KLK10,CEP70,AK7,CUL4B,EPHA4,SUDS3,NUDT12,NUP62CL,EPDR1,ASPHD2,APLP2,SP100,STIM1,NPNT,RGS3,FRYL,LMO4,WBP4,PTPRE,GM2A,FRS3,MBP,AURKB,ANLN,TRUB1,ENPP1,DUOX1,MPRIP,CAMK2N2,GPRC5B,LIMK1,BMP1,OVOL1,TLE1,AGFG2,CHMP4B,GLCCI1,SLC25A30,GRN,SERPINE2,ESRP1,SLC41A1,HERC5,C6orf106,SLC25A36,MYO5C,AKIRIN1,TUBGCP6,COL6A1,CD9,CKS1B,SNED1,EEF1D,DNAI1,MLEC,ZNF84,SALL4,DCP2,SOX13,CNTNAP1,ONECUT1,ITGA7,TMC5,FGF18,GDF11,ATP6V1C1,UBE2C,CXorf56,DOCK9 |
| 2.927e-02 | -3.53 | UDP_GLYCOSYLTRANSFERASE_ACTIVITY | MSigDB lists | UDP_GLYCOSYLTRANSFERASE_ACTIVITY | 41 | 11 | 17758 | 2588 |
GALNT3,B3GALNT1,UGT8,MGAT4A,XYLT1,MGAT4B,CSGALNACT1,GALNT7,POMGNT1,B4GALNT1,GCNT1 |
| 2.927e-02 | -3.53 | NAKAMURA_METASTASIS_MODEL_DN | MSigDB lists | NAKAMURA_METASTASIS_MODEL_DN | 41 | 11 | 17758 | 2588 |
TTC8,DDB2,SLCO4A1,RAC2,RUNX2,CAST,AK4,TMEM120A,SERPINB1,IRX3,RRAGD |
| 2.927e-02 | -3.53 | KEGG_BLADDER_CANCER | MSigDB lists | KEGG_BLADDER_CANCER | 41 | 11 | 17758 | 2588 |
CCND1,PGF,DAPK2,RB1,TYMP,CDH1,DAPK1,E2F1,TP53,ERBB2,EGFR |
| 2.928e-02 | -3.53 | SHIN_B_CELL_LYMPHOMA_CLUSTER_8 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_8 | 36 | 10 | 17758 | 2588 |
GNAS,IL15,NFKBIA,STAT1,HDAC1,WNT3A,CCNB1,CCNB2,ICAM1,FAS |
| 2.928e-02 | -3.53 | REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING | MSigDB lists | REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING | 36 | 10 | 17758 | 2588 |
AKT1,PTEN,NR4A1,CASP9,PIK3R1,PIK3CA,NRG2,CDKN1B,NRG1,PHLPP1 |
| 2.928e-02 | -3.53 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | MSigDB lists | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | 36 | 10 | 17758 | 2588 |
CASP3,FNTA,CASP7,ADD1,CTNNB1,CDH1,PRKCQ,BCAP31,LMNA,OCLN |
| 2.928e-02 | -3.53 | REACTOME_PI3K_AKT_ACTIVATION | MSigDB lists | REACTOME_PI3K_AKT_ACTIVATION | 36 | 10 | 17758 | 2588 |
IRS2,RHOA,AKT1,PTEN,NR4A1,CASP9,PIK3R1,PIK3CA,CDKN1B,PHLPP1 |
| 2.928e-02 | -3.53 | QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | MSigDB lists | QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | 36 | 10 | 17758 | 2588 |
COL6A2,PLOD2,MPP2,DUSP10,AES,CTNND1,BCL2L1,CITED2,KDM3A,F2RL1 |
| 2.928e-02 | -3.53 | REACTOME_GAB1_SIGNALOSOME | MSigDB lists | REACTOME_GAB1_SIGNALOSOME | 36 | 10 | 17758 | 2588 |
AKT1,PTEN,NR4A1,CASP9,PIK3R1,PIK3CA,CDKN1B,PHLPP1,GAB1,EGFR |
| 2.931e-02 | -3.53 | lower_leg | COSMIC cancer mutations | lower_leg | 175 | 35 | 17775 | 2585 |
TAOK2,RET,TP53,ERBB2,NOTCH2,FLT3,AIP,LMNA,HLA-A,KIF5B,CTNNB1,PTEN,SMO,PIK3CA,PTPRE,ALDH3A2,MYO5A,ADAMTS2,AKT1,TACC1,CEP89,PIK3R1,PTPRH,TNS1,COL7A1,SLC17A5,IDH1,GNA11,EGFR,TNS4,EPHA10,PLCH1,PTPRJ,FGFR2,PTK7 |
| 2.932e-02 | -3.53 | Znf_hrmn_rcpt | interpro domains | IPR001628 | 46 | 12 | 18293 | 2672 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 2.940e-02 | -3.53 | V$PIT1_Q6 | MSigDB lists | V$PIT1_Q6 | 222 | 43 | 17758 | 2588 |
INPPL1,ACVR1,PAX6,LRRFIP2,CPEB4,KLHL13,CAST,THRA,ETV5,UBE2Z,ZNF385B,GBX2,CCND1,FOXP2,PSMD1,PPP1R10,ANKS1B,LHX6,SGK3,ZDHHC23,TWIST1,MANF,OSBPL7,CITED2,SCN3A,TMCC2,CASK,SERTAD4,DCHS1,VAMP3,ATP1B1,LDB2,TMTC2,PPP1R14C,TCEAL8,XKRX,PITX2,RTN4RL1,COL13A1,HOXA9,PAPD5,SEMA3A,MAFF |
| 2.940e-02 | -3.53 | PRDX2 (peroxiredoxin 2) | protein interactions | 7001 | 87 | 21 | 16036 | 2547 |
SOD1,TXN,LAP3,SAT1,CUL1,NANS,PKM,SPR,PCBP1,CDK1,TIPRL,PRDX4,DAZAP1,UBE2T,PRDX3,BAX,TMEM9,PPP2R5D,ANXA11,MSH6,GPX4 |
| 2.947e-02 | -3.52 | AFFAR_YY1_TARGETS_DN | MSigDB lists | AFFAR_YY1_TARGETS_DN | 228 | 44 | 17758 | 2588 |
FOXM1,CDCA3,KIF23,RACGAP1,TGFBR1,KIF2C,CHST2,TOP2A,TFAP4,SPP1,CCNA2,PRC1,MSH2,POF1B,KIF22,BUB1,MXD3,HMMR,PVRL4,PLK1,NLRP4,FADS2,CENPA,KIF20A,ASPM,SPA17,AURKB,SLC25A5,CDC25C,IDH1,STEAP1,PRDX4,SOCS3,EDNRA,SFXN1,IL1R1,SERPINA1,SLC4A4,LRIG1,MATN2,AURKA,CENPE,PER3,CCNB2 |
| 2.947e-02 | -3.52 | V$NFKAPPAB65_01 | MSigDB lists | V$NFKAPPAB65_01 | 228 | 44 | 17758 | 2588 |
BMF,SDC4,TP53,FLOT1,BLCAP,TRIB2,DDR1,NFAT5,SIX4,BMP2K,ICAM1,RND1,IER3,CXCL16,SLC16A6,IL6ST,SLC44A1,MITF,CD70,RFX5,NFKB2,SLC12A2,DOCK4,WNT10B,TNIP1,ATP1B1,CD40,ILK,PNKD,CLCN2,TRIM47,TBC1D17,STAT6,RAP2C,NFKBIA,MAP3K11,UACA,NXPH4,FAM117A,SP6,JAK3,PTGES,COL16A1,CTDSP1 |
| 2.947e-02 | -3.52 | V$BACH2_01 | MSigDB lists | V$BACH2_01 | 258 | 49 | 17758 | 2588 |
CMAS,ENO2,CAPN12,SCOC,NUAK1,CAMKK1,SLC41A1,CALB2,NDRG2,RNF182,DHRS3,S100A2,NCS1,LMNA,BMP2,VASP,SHC3,SLC16A6,SGK1,TNFRSF12A,ABCD1,NTN4,MYH14,TAGLN2,TINAGL1,PIM1,GFI1,TRAK2,CAPN6,CTNNAL1,NR4A1,DENND1B,RGAG1,STRADB,KBTBD8,CAPNS1,SYP,COL7A1,KDM3A,MAP3K6,PRX,GABARAPL1,TRIM9,CAB39,DYSF,HS3ST3B1,EFNA1,MAMDC2,FOXA1 |
| 2.951e-02 | -3.52 | V$LFA1_Q6 | MSigDB lists | V$LFA1_Q6 | 234 | 45 | 17758 | 2588 |
SLC2A4,ARAP3,TRIP10,PPM1J,HEBP1,FXYD3,BACE1,XYLT1,GABRG2,CCNL1,BAHD1,NFAT5,SIX4,M6PR,RABGGTA,VASP,SESN3,CTGF,SH3BP1,ZFP36,PPP1R16A,BAX,BCL6,IQCD,NPTXR,ARL4D,GAD1,TPCN1,TUBA4A,OLFML2A,HES1,ASXL1,ACVR1C,NR4A1,KIF1C,TCF7,NPC2,RASGRP2,NFKBIA,RAB31,S100A5,PITPNA,OSR1,NRGN,DMPK |
| 2.951e-02 | -3.52 | NABA_ECM_REGULATORS | MSigDB lists | NABA_ECM_REGULATORS | 234 | 45 | 17758 | 2588 |
SERPINE2,ST14,P3H2,CTSB,SERPINB9,CTSZ,ADAMTSL4,CD109,TIMP1,CTSC,FAM20C,CST3,FAM20B,ADAM15,CTSD,EGLN3,LOXL1,SULF2,ADAMTS2,ADAM17,TIMP2,LOXL2,F12,CTSL,MMP15,TIMP3,SERPINA1,HPSE,PLOD2,P4HA2,MMP17,CTSV,P4HA3,BMP1,SERPINB5,ADAMTS14,SERPINB6,CTSA,SERPINI1,PLOD3,SERPINB1,EGLN1,PCSK5,TLL2,ADAMTS16 |
| 2.952e-02 | -3.52 | V$NFY_Q6 | MSigDB lists | V$NFY_Q6 | 246 | 47 | 17758 | 2588 |
IER5L,SORT1,PAX6,UGP2,ALDH6A1,CIT,DCAF7,RACGAP1,RAB6A,CRABP2,SEPT4,BAHD1,GNB2,SIX4,SLC25A35,M6PR,TOP2A,CDH1,FDXR,NEK2,MSH2,BUB1,PXMP4,DLG3,TIAM1,SPRY2,NEB,CKS2,GCA,MLEC,RHOA,KBTBD8,LDB2,TYSND1,CDK1,VCP,ACYP1,PRCP,WDR19,SPAG7,HDAC1,AGFG2,NUP37,E2F8,JARID2,WDR63,TLL2 |
| 2.957e-02 | -3.52 | NEGATIVE_REGULATION_OF_CELL_CYCLE | MSigDB lists | NEGATIVE_REGULATION_OF_CELL_CYCLE | 78 | 18 | 17758 | 2588 |
CDKN1C,TP53,CUL1,RUNX3,NOTCH2,SESN1,RHOB,CDKN2C,CDK5RAP1,BMP2,BTG3,DHRS2,BMP7,DLG1,CDKN1B,HEXIM2,CDKN2D,MAPK12 |
| 2.957e-02 | -3.52 | MORF_ATOX1 | MSigDB lists | MORF_ATOX1 | 78 | 18 | 17758 | 2588 |
SOD1,SHMT1,PSMB4,TCEB2,SEC61G,PSMD7,MORF4L2,BCAP31,DNPEP,FAM20B,PPP2R4,PGRMC1,TMBIM6,PLOD3,PSMC1,MYL12B,TMED2,PRKAR1A |
| 2.957e-02 | -3.52 | KEGG_PEROXISOME | MSigDB lists | KEGG_PEROXISOME | 78 | 18 | 17758 | 2588 |
SOD1,PEX6,AGPS,SOD2,IDH1,NUDT12,ABCD4,PEX5,PEX2,ECI2,HMGCL,ABCD1,ACSL4,ACOX2,FAR2,PXMP4,FAR1,XDH |
| 2.957e-02 | -3.52 | superpathway of inositol phosphate compounds | BIOCYC pathways | HUMAN_PWY-6371 | 66 | 19 | 907 | 172 |
INPPL1,TMEM55B,INPP5D,PIK3R1,PIP4K2C,CDIPT,PI4K2B,PLCH1,PLCG1,PTEN,OCRL,PLCG2,PIK3CA,PIK3C2B,PIK3CD,MINPP1,ITPKA,PIKFYVE,PLCB2 |
| 2.959e-02 | -3.52 | The phototransduction cascade | REACTOME pathways | R-HSA-2514856 | 35 | 10 | 8202 | 1235 |
CALM2,RGS9,FNTA,GNB5,CALM1,CALM3,PRKCQ,CNGA1,NMT2,METAP2 |
| 2.961e-02 | -3.52 | RasGEFN | smart domains | SM00229 | 20 | 7 | 9131 | 1455 |
RASGRF1,RASGRP3,RASGEF1A,RAPGEF2,KNDC1,RASGRP1,RASGRP2 |
| 2.961e-02 | -3.52 | positive regulation of Wnt signaling pathway | biological process | GO:0030177 | 165 | 34 | 16441 | 2455 |
LGR4,PSME2,PSMD7,XIAP,PSMD10,PSME1,PPP2R3A,BMP2,PSMD1,RNF220,CTNNB1,DACT1,PSMC2,DIXDC1,ZRANB1,WNT3A,PSMA5,DVL2,SULF2,WNT10B,PSMB4,ASPM,AMER1,ILK,PSMA4,GPRC5B,ANKRD6,FGFR2,PSMD3,NKD1,LRRK1,FZD5,PSMC1,RNF146 |
| 2.962e-02 | -3.52 | POMK (protein-O-mannose kinase) | protein interactions | 84197 | 57 | 15 | 16036 | 2547 |
KDSR,GOLIM4,XYLT2,TMBIM6,TGFBR1,POMGNT1,TMEM120A,B4GALT3,POMT1,REEP4,TNFSF9,GNB2,FAM134C,CERS2,FAM69A |
| 2.966e-02 | -3.52 | IL6-mediated signaling events | Pathway Interaction DB | il6_7pathway | 43 | 15 | 2227 | 480 |
PIAS3,HSP90B1,TIMP1,JAK1,AKT1,IL6ST,LMO4,PIK3R1,MITF,STAT1,PIK3CA,MAPK11,FOS,IRF1,SOCS3 |
| 2.975e-02 | -3.51 | RGS | pfam domains | PF00615 | 35 | 10 | 16629 | 2504 |
SNX13,RGS9,RGS12,ADRBK1,RGS3,RGS20,RGS5,GRK6,RGS14,ADRBK2 |
| 2.977e-02 | -3.51 | regulation of DNA binding | biological process | GO:0051101 | 87 | 20 | 16441 | 2455 |
ZNF462,HES1,TXN,HJURP,PLAUR,HABP4,PPARA,GATA3,NFIB,PER2,CTNNBIP1,TFAP4,SP100,NFKBIA,SMO,E2F1,NEK2,TWIST1,ERCC2,MDFI |
| 2.978e-02 | -3.51 | IGBP1 (immunoglobulin (CD79A) binding protein 1) | protein interactions | 3476 | 113 | 26 | 16036 | 2547 |
OTUD5,LOC81691,PSRC1,LGALS3,S100A11,SH3BGRL,NDRG1,S100A4,VPS4B,NENF,GLO1,MCFD2,PCBP1,MYL12A,TIPRL,SNX12,GINS4,MUC16,SP100,STAT6,STAT1,TAGLN2,PLIN3,PDIA6,HSPB1,S100A13 |
| 2.980e-02 | -3.51 | axilla | COSMIC cancer mutations | axilla | 187 | 37 | 17775 | 2585 |
KIAA1462,TP53,FLT3,DNER,CCND1,RB1,CTNNB1,PTEN,SMO,PIK3CA,STEAP3,MYT1,IL1RAP,ZNF117,FAM134C,ERAP2,CPD,AKT1,FOPNL,OGDHL,WHSC1,ERP44,IDH1,BBS2,EGFR,NIN,DHDH,PTPRF,FAT4,ACAD10,RCBTB2,ATP7B,NOD2,DYSF,ZNF165,LTA4H,COL16A1 |
| 2.985e-02 | -3.51 | human chr7q22 | chromosome location | human chr7q22 | 29 | 7 | 26250 | 2805 |
MOSPD3,PRKAR2B,EPHB4,PCOLCE,PLOD3,GNB2,GIGYF1 |
| 2.985e-02 | -3.51 | human chr17p13 | chromosome location | human chr17p13 | 29 | 7 | 26250 | 2805 |
TAX1BP3,CXCL16,SLC2A4,CTNS,FAM101B,SRR,USP6 |
| 2.992e-02 | -3.51 | positive regulation of carbohydrate metabolic process | biological process | GO:0045913 | 71 | 17 | 16441 | 2455 |
PRKAA2,SORBS1,AKT1,IL15,PFKFB2,PRKAA1,ARFGEF1,PPARA,P2RX7,PDGFB,GPLD1,IRS2,INSR,GPER1,PHKG2,ARNT,CHP1 |
| 2.992e-02 | -3.51 | negative regulation of phosphatase activity | biological process | GO:0010923 | 71 | 17 | 16441 | 2455 |
CAMSAP3,SPRED1,FARP1,BAG4,LMTK3,PPP4R4,PKMYT1,TIPRL,SYTL2,SH2D4A,SH3RF2,SEMA4D,PPP2R4,CRY2,DLG3,CHP1,ARFGEF3 |
| 2.992e-02 | -3.51 | hormone binding | molecular function | GO:0042562 | 66 | 16 | 16491 | 2452 |
THRB,SEC61B,ACVR1,NR3C1,CRYM,THRA,PIK3R1,CALR,INSR,IDE,ATP1A1,IGF1R,ALDH1A3,ADIPOR1,GPER1,ECE1 |
| 2.993e-02 | -3.51 | Prot-tyrosine_phosphatase-like | interpro domains | IPR029021 | 100 | 22 | 18293 | 2672 |
SSH3,MTM1,PTPN18,SSH1,PTPRU,PTPN9,DUSP23,TNS1,SBF1,DUSP4,DUSP5,EPM2A,PTPRF,TNS3,PTPRJ,PTEN,PALD1,MTMR10,DUSP10,MTMR11,PTPRE,DUSP1 |
| 3.000e-02 | -3.51 | ERBB2IP (erbb2 interacting protein) | protein interactions | 55914 | 77 | 19 | 16036 | 2547 |
CASK,MPP1,ARHGEF7,ERBB2,ERBB2IP,LRRC1,ZFYVE9,ABR,PICK1,CDH1,CTNNB1,MPP2,NOD2,ARVCF,CTNND1,PPP1CA,ABCA1,ATP2B1,MAPK12 |
| 3.002e-02 | -3.51 | ABCC4 (ATP binding cassette subfamily C member 4) | protein interactions | 10257 | 12 | 5 | 16036 | 2547 |
SNTA1,ERBB2IP,LGALS3,LGALS8,SLC9A3R2 |
| 3.002e-02 | -3.51 | TSPYL2 (TSPY-like 2) | protein interactions | 64061 | 12 | 5 | 16036 | 2547 |
CASK,CCNB1,CCNB2,CDK1,PSMD3 |
| 3.002e-02 | -3.51 | TNS3 (tensin 3) | protein interactions | 64759 | 12 | 5 | 16036 | 2547 |
ERBB2,TRIM47,ERBB3,DNPEP,EGFR |
| 3.002e-02 | -3.51 | RHOT1 (ras homolog family member T1) | protein interactions | 55288 | 12 | 5 | 16036 | 2547 |
PINK1,IRAK1,ILK,AMFR,TRAK2 |
| 3.002e-02 | -3.51 | FKBP15 (FK506 binding protein 15) | protein interactions | 23307 | 12 | 5 | 16036 | 2547 |
LGR4,NUDT12,CDK19,FAM21C,VCP |
| 3.002e-02 | -3.51 | ZNF205 (zinc finger protein 205) | protein interactions | 7755 | 12 | 5 | 16036 | 2547 |
MEST,HDAC6,ILK,TRAF2,MDFI |
| 3.002e-02 | -3.51 | SPDEF (SAM pointed domain containing ETS transcription factor) | protein interactions | 25803 | 12 | 5 | 16036 | 2547 |
NKX3-1,FASTKD1,MYO5C,MECOM,C5orf30 |
| 3.002e-02 | -3.51 | GALNT2 (polypeptide N-acetylgalactosaminyltransferase 2) | protein interactions | 2590 | 12 | 5 | 16036 | 2547 |
TGOLN2,SLC25A4,FAM3C,ZMPSTE24,NOD2 |
| 3.002e-02 | -3.51 | PTPRZ1 (protein tyrosine phosphatase, receptor-type, Z polypeptide 1) | protein interactions | 5803 | 12 | 5 | 16036 | 2547 |
MDK,FYN,LGALS3,CTNNB1,ARHGAP35 |
| 3.002e-02 | -3.51 | POMGNT2 (protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)) | protein interactions | 84892 | 12 | 5 | 16036 | 2547 |
NRG1,ATP1B3,FBXO6,NPDC1,PLAUR |
| 3.010e-02 | -3.50 | negative regulation of neurogenesis | biological process | GO:0050768 | 223 | 44 | 16441 | 2455 |
SEMA6B,PAX6,ADGRG1,CIT,LRP4,EPHA4,SOX9,TP53,TP73,CALR,SPP1,CTNNB1,PTEN,BMP7,KIAA0319,SORL1,DUSP10,DIXDC1,NOTCH3,SEMA3G,WNT3A,NTN1,GFI1,ITM2C,SEMA3B,HES1,RHOA,ASPM,RAPGEF2,ULK2,CDK5R1,DPYSL3,IRX3,SEMA4D,PLK2,RAB29,NRG1,EFNA1,GDF11,ARF6,SOX8,SEMA3A,NGEF,CTDSP1 |
| 3.014e-02 | -3.50 | CCNE1 (cyclin E1) | protein interactions | 898 | 72 | 18 | 16036 | 2547 |
SMARCA2,FOXM1,CUL4B,CALM1,MYBL2,HERC5,CDK1,TP73,RB1,PCNA,CTNNB1,H1F0,RBL1,PRC1,E2F1,CDKN1B,TUBG1,PRKAR1A |
| 3.014e-02 | -3.50 | DNM1 (dynamin 1) | protein interactions | 1759 | 72 | 18 | 16036 | 2547 |
MOB4,BIN1,PACSIN2,PIK3R1,GRIN1,ASB13,SNX9,SH3KBP1,IRF2BPL,PLCG1,LYPD6,DNM2,SH3BP4,ARRB1,GRIN2D,CABIN1,CTTN,PACSIN1 |
| 3.021e-02 | -3.50 | anus | COSMIC cancer mutations | anus | 13 | 5 | 17775 | 2585 |
CTNNB1,GNA11,EGFR,PIK3CA,TP53 |
| 3.021e-02 | -3.50 | chest_wall | COSMIC cancer mutations | chest_wall | 13 | 5 | 17775 | 2585 |
IDH1,EGFR,RET,PIK3CA,TP53 |
| 3.021e-02 | -3.50 | upper_aerodigestive_tract-pharynx-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma | 13 | 5 | 17775 | 2585 |
CDKN2C,RB1,CTNNB1,PIK3CA,TP53 |
| 3.021e-02 | -3.50 | bone-maxilla-other-ameloblastoma | COSMIC cancer mutations | bone-maxilla-other-ameloblastoma | 13 | 5 | 17775 | 2585 |
CTNNB1,JAK3,FGFR2,SMO,PIK3CA |
| 3.021e-02 | -3.50 | soft_tissue-fat-lipoma | COSMIC cancer mutations | soft_tissue-fat-lipoma | 13 | 5 | 17775 | 2585 |
GNAS,ERBB2,RB1,CTNNB1,AKT1 |
| 3.021e-02 | -3.50 | cervix-carcinoma-adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-adenocarcinoma | 13 | 5 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 3.021e-02 | -3.50 | endometrium-ovary-endometriosis | COSMIC cancer mutations | endometrium-ovary-endometriosis | 13 | 5 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53 |
| 3.021e-02 | -3.50 | radius | COSMIC cancer mutations | radius | 13 | 5 | 17775 | 2585 |
GNAS,IDH1,EGFR,PIK3CA,TP53 |
| 3.021e-02 | -3.50 | sarcomatous-fibrous | COSMIC cancer mutations | sarcomatous-fibrous | 13 | 5 | 17775 | 2585 |
SS18,CTNNB1,PTEN,EGFR,PIK3CA |
| 3.021e-02 | -3.50 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Burkitt_lymphoma | 13 | 5 | 17775 | 2585 |
RB1,FLT3,PTEN,PIK3CA,TP53 |
| 3.023e-02 | -3.50 | GENTILE_RESPONSE_CLUSTER_D3 | MSigDB lists | GENTILE_RESPONSE_CLUSTER_D3 | 62 | 15 | 17758 | 2588 |
CNOT2,SERTAD2,SSH1,CYR61,PLK4,KIF23,TRAPPC8,BLCAP,ACADM,ZMIZ1,ZFAND5,TIPARP,RHOB,STK17A,CKS2 |
| 3.023e-02 | -3.50 | GCM_ERBB2IP | MSigDB lists | GCM_ERBB2IP | 62 | 15 | 17758 | 2588 |
NAPG,ARAP2,WDR11,CASC4,FRYL,IMPAD1,OTUD6B,IL6ST,DDHD2,DLG1,CAB39,KIAA1109,ERBB2IP,NPTN,BBS2 |
| 3.023e-02 | -3.50 | CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | MSigDB lists | CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | 62 | 15 | 17758 | 2588 |
PTPN18,CTGF,AGPS,CNOT8,DGKA,GRIN1,PBX3,CTNND1,IL27RA,STK39,MYBL1,GAB1,AIP,ANXA11,FAM134C |
| 3.023e-02 | -3.50 | LEE_LIVER_CANCER_E2F1_UP | MSigDB lists | LEE_LIVER_CANCER_E2F1_UP | 62 | 15 | 17758 | 2588 |
KIAA1462,PLSCR1,ETS2,CD63,USP18,GPC3,GGH,TAGLN2,NUCB2,CPE,CYP39A1,CASP4,LEPR,RHOB,XDH |
| 3.023e-02 | -3.50 | REACTOME_SIGNALING_BY_WNT | MSigDB lists | REACTOME_SIGNALING_BY_WNT | 62 | 15 | 17758 | 2588 |
PSMD1,PPP2R5A,PSMB4,CTNNB1,PSME2,PSMD3,PSMC2,PSMD7,PSMD10,CUL1,PSME1,PPP2R5D,PSMC1,PSMA4,PSMA5 |
| 3.023e-02 | -3.50 | REN_BOUND_BY_E2F | MSigDB lists | REN_BOUND_BY_E2F | 62 | 15 | 17758 | 2588 |
TOP2A,RB1,PCNA,CENPA,CCNA2,RBL1,PTTG1,NDC80,TP53,MSH2,CENPE,BARD1,CBX5,CDK1,SMC4 |
| 3.023e-02 | -3.50 | human chr1p32 | chromosome location | human chr1p32 | 23 | 6 | 26250 | 2805 |
TESK2,CDKN2C,TACSTD2,STIL,CPT2,RNF11 |
| 3.025e-02 | -3.50 | NRP1 (neuropilin 1) | protein interactions | 8829 | 38 | 11 | 16036 | 2547 |
PGF,TGFBR3,TMEM30A,TGFBR1,PLXND1,PLXNA1,SEMA3A,PDGFB,L1CAM,NRP2,SEMA3B |
| 3.025e-02 | -3.50 | DHPS (deoxyhypusine synthase) | protein interactions | 1725 | 38 | 11 | 16036 | 2547 |
CDK17,KCNAB3,DHPS,PTPRH,EIF5A2,PLIN3,DPP8,VASH1,ARF6,RAB27B,PPP2R5D |
| 3.027e-02 | -3.50 | Nucleotide-diphossugar_trans | interpro domains | IPR029044 | 89 | 20 | 18293 | 2672 |
CHSY3,CMAS,UGP2,CERCAM,GALNT12,GYLTL1B,GALNT7,POMGNT1,B4GALT4,EXT2,GLT8D2,B4GALNT1,GALNT3,UAP1,PLOD2,MGAT1,A4GALT,CSGALNACT1,PLOD3,B4GALT3 |
| 3.028e-02 | -3.50 | FN3 | prosite domains | PS50853 | 191 | 39 | 11866 | 1802 |
EPHA4,IL27RA,IL13RA1,MERTK,IL22RA1,NEO1,PHYHIP,IGSF9,IGF1R,IL6ST,VASN,FLRT3,IL31RA,ANKFN1,SORL1,EPHB4,NCAM1,IL10RB,SNED1,IGDCC4,PTPRU,VWA1,COL7A1,EPHA1,FNDC3A,MYOM1,LEPR,COL12A1,TRIM9,PTPRF,EPHA10,INSR,PTPRJ,AXL,MYLK,OSMR,L1CAM,POMGNT2,LIFR |
| 3.028e-02 | -3.50 | limb development | biological process | GO:0060173 | 171 | 35 | 16441 | 2455 |
RUNX2,GRHL2,ITGA6,LRP4,SOX9,RAB23,OSR2,CRABP2,FZD6,MECOM,CTNNB1,MEGF8,IMPAD1,GPC3,FRAS1,BMP7,TFAP2A,BAX,TWIST1,ECE1,CYP26B1,SALL4,FMN1,RC3H2,PITX2,GNAS,FGFR2,HOXA9,TRAF3IP1,HDAC1,OSR1,SHOX2,RARG,HOXC13,PCSK5 |
| 3.028e-02 | -3.50 | appendage development | biological process | GO:0048736 | 171 | 35 | 16441 | 2455 |
RUNX2,GRHL2,ITGA6,LRP4,SOX9,RAB23,OSR2,CRABP2,FZD6,MECOM,CTNNB1,MEGF8,IMPAD1,GPC3,FRAS1,BMP7,TFAP2A,BAX,TWIST1,ECE1,CYP26B1,SALL4,FMN1,RC3H2,PITX2,GNAS,FGFR2,HOXA9,TRAF3IP1,HDAC1,OSR1,SHOX2,RARG,HOXC13,PCSK5 |
| 3.028e-02 | -3.50 | positive regulation of protein complex assembly | biological process | GO:0031334 | 171 | 35 | 16441 | 2455 |
PINK1,BMF,BIK,TP53,HDAC6,SNX9,ICAM1,VASP,CTNNB1,PSMC2,TUBGCP6,MITF,GTF2F2,BAX,DLG1,CAPG,FNIP1,CDKN1B,TWIST1,SLAIN2,CTTN,RHOA,BAG4,PSRC1,WNT10B,FMN1,LCP1,VCP,FAS,IDE,PIEZO1,ARF6,ARPC2,AHR,PSMC1 |
| 3.041e-02 | -3.49 | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 181 | 36 | 17758 | 2588 |
DDX58,GCLM,CMAS,SORT1,ADO,XYLT1,TMX4,SELL,SAMD9,HERC6,FAM101B,KIAA1147,DTX3L,CD46,PCNA,TRANK1,METTL7A,ZNRF2,APIP,PIK3CD,CRTAP,SSH3,LPGAT1,NUB1,SYNE2,UTRN,IFIT3,ALCAM,PGF,BOLA3,IDE,ACADSB,TIMM8A,C19orf66,F2RL1,DEF6 |
| 3.041e-02 | -3.49 | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | 181 | 36 | 17758 | 2588 |
FTH1,EGR3,SLC9A7,DNAJB9,RAVER2,SAP130,OTUD1,CTNNB1,SLC16A6,FOSB,N4BP3,SGK1,TIPARP,DUSP1,MARK1,RIPK2,TACC1,NR4A1,COQ10B,SAT1,PTGER4,UTRN,TMEM98,ZFAND5,FOS,TP53INP2,TRIM7,RHOB,SOCS3,CD83,PTGS2,PLK2,KBTBD2,NR4A3,ZMIZ1,JARID2 |
| 3.041e-02 | -3.49 | CYCLIN_D1_UP.V1_UP | MSigDB lists | CYCLIN_D1_UP.V1_UP | 181 | 36 | 17758 | 2588 |
BIN1,CASP3,FAM189A2,HSPG2,CPT2,RPS6KA1,DCAF7,RASSF7,TAP1,ZYX,SHC3,FDXR,GALNS,ABCA2,GOT1,KIF22,ETV4,MYT1,MGAT5,ALDH3A2,RASGRF1,WNT10B,BCL9,FHL2,KLK6,MMP15,ETS2,CGREF1,RAB31,BMP1,GLB1,HOXB13,DMWD,FZD5,TRPC3,FGD1 |
| 3.043e-02 | -3.49 | THIOL_PROTEASE_CYS | prosite domains | PS00139 | 21 | 7 | 11866 | 1802 |
CTSL,CAPN2,CAPN12,CTSC,CTSB,CTSV,CAPN1 |
| 3.043e-02 | -3.49 | FERM_1 | prosite domains | PS00660 | 21 | 7 | 11866 | 1802 |
EPB41L5,EZR,FARP1,FRMD4A,NF2,EPB41L4A,FARP2 |
| 3.043e-02 | -3.49 | FE2OG_OXY | prosite domains | PS51471 | 21 | 7 | 11866 | 1802 |
PLOD3,EGLN3,PLOD2,P3H2,P4HA2,P4HA3,EGLN1 |
| 3.043e-02 | -3.49 | DH_1 | prosite domains | PS00741 | 21 | 7 | 11866 | 1802 |
RASGRF1,ARHGEF3,TIAM1,ARHGEF7,MCF2L,ABR,ARHGEF4 |
| 3.043e-02 | -3.49 | - | gene3d domains | 1.25.40.280 | 5 | 3 | 9988 | 1574 |
RHPN2,BROX,RHPN1 |
| 3.043e-02 | -3.49 | - | gene3d domains | 3.30.43.10 | 5 | 3 | 9988 | 1574 |
AGPS,XDH,AOX1 |
| 3.043e-02 | -3.49 | - | gene3d domains | 1.10.1450.10 | 5 | 3 | 9988 | 1574 |
CD81,TSPAN6,CD9 |
| 3.043e-02 | -3.49 | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | MSigDB lists | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | 123 | 26 | 17758 | 2588 |
GRN,PLK1,QSOX1,LGALS3,S100A11,IQGAP1,S100A4,TAP1,LITAF,CYB561,PDK3,SPTLC2,SNX12,STX3,SIRPA,CYP26A1,TAPBP,NCOA3,PROM1,CTSC,STAT1,NFKBIZ,ATP1B3,LGMN,SNX10,S100A6 |
| 3.044e-02 | -3.49 | ZBTB2 (zinc finger and BTB domain containing 2) | protein interactions | 57621 | 16 | 6 | 16036 | 2547 |
HDAC1,RASSF8,ZNF219,P4HB,STAT6,TP53 |
| 3.044e-02 | -3.49 | ENG (endoglin) | protein interactions | 2022 | 16 | 6 | 16036 | 2547 |
BMP2,TGFBR1,ACVR1,TGFBR3,ACVRL1,BMP7 |
| 3.044e-02 | -3.49 | TBC1D9B (TBC1 domain family, member 9B (with GRAM domain)) | protein interactions | 23061 | 16 | 6 | 16036 | 2547 |
MAP1LC3B,ALDH3A2,TMEM55B,VCP,SPINT2,GABARAPL1 |
| 3.044e-02 | -3.49 | ELL3 (elongation factor RNA polymerase II-like 3) | protein interactions | 80237 | 16 | 6 | 16036 | 2547 |
SIRT1,FTH1,EAF2,ADD3,TP53,CDK14 |
| 3.044e-02 | -3.49 | SYTL4 (synaptotagmin-like 4) | protein interactions | 94121 | 16 | 6 | 16036 | 2547 |
FXR2,SYTL4,CEP70,RAB27B,ZBTB7B,STX3 |
| 3.044e-02 | -3.49 | REACTOME_S_PHASE | MSigDB lists | REACTOME_S_PHASE | 106 | 23 | 17758 | 2588 |
CCNE2,PSMB4,PSME2,PSMD7,PSMD10,CUL1,PSME1,POLD3,PSMA4,GINS4,PRIM1,CCND1,WEE1,RB1,CCNA2,PSMD1,PCNA,PSMD3,PSMC2,CKS1B,CDKN1B,PSMC1,PSMA5 |
| 3.044e-02 | -3.49 | KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 106 | 23 | 17758 | 2588 |
RHOA,NFKBIE,AKT1,PIK3R1,PRKCQ,CBL,FOS,NFAT5,BCL10,PAK6,PLCG1,CD8A,FYN,NFKBIA,PAK2,DLG1,PIK3CA,MAPK13,MAPK11,PIK3CD,MAP3K7,RASGRP1,MAPK12 |
| 3.044e-02 | -3.49 | GCM_CALM1 | MSigDB lists | GCM_CALM1 | 106 | 23 | 17758 | 2588 |
CLCN3,ZNF84,GPR107,NUAK1,ADO,STMN3,NCKAP1,PJA2,APC2,MAPK8IP1,ZNF275,APPBP2,MAP1B,CCDC92,NAPG,DDAH1,SESN3,PPME1,TMEM30A,MCF2L,TNPO2,NCAM1,NDFIP1 |
| 3.047e-02 | -3.49 | BIOCARTA_P27_PATHWAY | MSigDB lists | BIOCARTA_P27_PATHWAY | 13 | 5 | 17758 | 2588 |
CKS1B,CDKN1B,CUL1,RB1,E2F1 |
| 3.047e-02 | -3.49 | MODULE_143 | MSigDB lists | MODULE_143 | 13 | 5 | 17758 | 2588 |
HLA-B,HLA-C,HLA-E,HLA-F,HLA-A |
| 3.047e-02 | -3.49 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_OLD | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_OLD | 13 | 5 | 17758 | 2588 |
TP53I11,NDRG1,SYK,SOX9,FLOT1 |
| 3.047e-02 | -3.49 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | MSigDB lists | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | 13 | 5 | 17758 | 2588 |
FYN,PLXNA1,SEMA3A,RND1,FARP2 |
| 3.047e-02 | -3.49 | NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | MSigDB lists | NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | 13 | 5 | 17758 | 2588 |
CDKN1B,CDKN2C,NF2,CDKN2D,PPP2R4 |
| 3.047e-02 | -3.49 | LOPEZ_MESOTELIOMA_SURVIVAL_TIME_UP | MSigDB lists | LOPEZ_MESOTELIOMA_SURVIVAL_TIME_UP | 13 | 5 | 17758 | 2588 |
AURKA,FAM64A,CDC25C,MELK,ACOT7 |
| 3.047e-02 | -3.49 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_UP | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_UP | 13 | 5 | 17758 | 2588 |
ATP8B1,TCF7,HSPB1,DPYSL2,RGS20 |
| 3.047e-02 | -3.49 | BIOCARTA_CACAM_PATHWAY | MSigDB lists | BIOCARTA_CACAM_PATHWAY | 13 | 5 | 17758 | 2588 |
CALM2,CALM3,CAMKK1,CAMK2G,CALM1 |
| 3.047e-02 | -3.49 | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | 13 | 5 | 17758 | 2588 |
LTBP2,TNIP1,F2RL1,SPSB1,PLAUR |
| 3.047e-02 | -3.49 | EXTRINSIC_TO_PLASMA_MEMBRANE | MSigDB lists | EXTRINSIC_TO_PLASMA_MEMBRANE | 13 | 5 | 17758 | 2588 |
GNAS,ARRB1,SYTL4,APC2,SYTL2 |
| 3.047e-02 | -3.49 | VERRECCHIA_RESPONSE_TO_TGFB1_C4 | MSigDB lists | VERRECCHIA_RESPONSE_TO_TGFB1_C4 | 13 | 5 | 17758 | 2588 |
RAC2,NOTCH2,COL16A1,MMP17,PAK2 |
| 3.047e-02 | -3.49 | LUI_THYROID_CANCER_CLUSTER_5 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_5 | 13 | 5 | 17758 | 2588 |
ACADM,ETHE1,TSPAN1,BLVRB,EPHX1 |
| 3.047e-02 | -3.49 | SYNAPSE_PART | MSigDB lists | SYNAPSE_PART | 13 | 5 | 17758 | 2588 |
NPTN,MAGEE1,CABP1,PICK1,DNM2 |
| 3.047e-02 | -3.49 | REGULATION_OF_CELL_SHAPE | MSigDB lists | REGULATION_OF_CELL_SHAPE | 13 | 5 | 17758 | 2588 |
FGD6,TAOK2,ARAP3,ARAP1,FGD1 |
| 3.049e-02 | -3.49 | MHC protein binding | molecular function | GO:0042287 | 26 | 8 | 16491 | 2452 |
MARCH8,CD8A,TAPBP,TUBB4B,HLA-E,TAP1,BCAP31,VCP |
| 3.049e-02 | -3.49 | histone acetyltransferase binding | molecular function | GO:0035035 | 26 | 8 | 16491 | 2452 |
PCNA,PAX6,EPAS1,TP53,NR4A3,CITED2,ETS1,TRIM68 |
| 3.056e-02 | -3.49 | epidermal_nevus | COSMIC cancer mutations | epidermal_nevus | 9 | 4 | 17775 | 2585 |
AKT1,PTEN,SMO,PIK3CA |
| 3.056e-02 | -3.49 | pancreas-carcinoid-endocrine_tumour-glucagonoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-glucagonoma | 9 | 4 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,PTEN |
| 3.056e-02 | -3.49 | mixed_endometrioid_and_clear_cell_carcinoma | COSMIC cancer mutations | mixed_endometrioid_and_clear_cell_carcinoma | 9 | 4 | 17775 | 2585 |
CTNNB1,FGFR2,PTEN,PIK3CA |
| 3.056e-02 | -3.49 | glucagonoma | COSMIC cancer mutations | glucagonoma | 9 | 4 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,PTEN |
| 3.056e-02 | -3.49 | peritoneum-mesothelioma-epithelial | COSMIC cancer mutations | peritoneum-mesothelioma-epithelial | 9 | 4 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,PIK3CA |
| 3.056e-02 | -3.49 | chondroma | COSMIC cancer mutations | chondroma | 9 | 4 | 17775 | 2585 |
GNAS,ERBB2,IDH1,TP53 |
| 3.056e-02 | -3.49 | upper_aerodigestive_tract-larynx-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-larynx-carcinoma | 9 | 4 | 17775 | 2585 |
CDKN2C,ERBB2,EGFR,TP53 |
| 3.056e-02 | -3.49 | central_nervous_system-frontal_lobe-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-oligodendroglioma_Grade_III | 9 | 4 | 17775 | 2585 |
CDKN2C,IDH1,MSH6,MSH2 |
| 3.056e-02 | -3.49 | hamartoma | COSMIC cancer mutations | hamartoma | 9 | 4 | 17775 | 2585 |
GNAS,TSC1,CTNNB1,TP53 |
| 3.056e-02 | -3.49 | lung-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | lung-carcinoma-adenoid_cystic_carcinoma | 9 | 4 | 17775 | 2585 |
KIF5B,RB1,CCDC6,EGFR |
| 3.058e-02 | -3.49 | sulfuric ester hydrolase activity | molecular function | GO:0008484 | 17 | 6 | 16491 | 2452 |
GNS,ARSB,ARSG,ARSK,GALNS,SULF2 |
| 3.058e-02 | -3.49 | transmembrane receptor protein serine/threonine kinase activity | molecular function | GO:0004675 | 17 | 6 | 16491 | 2452 |
LTBP1,TGFBR1,ACVR1,TGFBR3,ACVRL1,ACVR1C |
| 3.058e-02 | -3.49 | nitric-oxide synthase binding | molecular function | GO:0050998 | 17 | 6 | 16491 | 2452 |
CALM3,CALM2,SNTA1,SCN5A,CALM1,DNM2 |
| 3.060e-02 | -3.49 | NRAGE signals death through JNK | REACTOME pathways | R-HSA-193648 | 45 | 12 | 8202 | 1235 |
ARHGEF3,ARHGEF11,MCF2L,ARHGEF7,ARHGAP4,TIAM1,ARHGEF9,ABR,ARHGEF16,ARHGEF4,FGD1,NGEF |
| 3.060e-02 | -3.49 | Pre-NOTCH Expression and Processing | REACTOME pathways | R-HSA-1912422 | 45 | 12 | 8202 | 1235 |
CCND1,TNRC6C,LFNG,E2F1,TP53,FURIN,AGO4,MAML2,NOTCH3,NOTCH2,RAB6A,TMED2 |
| 3.065e-02 | -3.49 | human chr5q21 | chromosome location | human chr5q21 | 7 | 3 | 26250 | 2805 |
EFNA5,CPEB4,GNPDA1 |
| 3.065e-02 | -3.49 | human chr10q21 | chromosome location | human chr10q21 | 7 | 3 | 26250 | 2805 |
ADAMTS14,CCDC6,SGPL1 |
| 3.065e-02 | -3.49 | human chr12p11 | chromosome location | human chr12p11 | 7 | 3 | 26250 | 2805 |
PKP2,MRPS35,ITPR2 |
| 3.065e-02 | -3.49 | human chr13q22.1 | chromosome location | human chr13q22.1 | 7 | 3 | 26250 | 2805 |
KLF5,MZT1,BORA |
| 3.066e-02 | -3.48 | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 187 | 37 | 17758 | 2588 |
TBC1D1,RASSF7,HEXB,BTN3A1,CYB561,VASH1,SLC20A1,LGALS3BP,PDIA4,ELF3,DIRAS3,EPCAM,PSMD1,SP100,CTNNB1,PPP1R10,SH3BP1,RALB,CD70,S100A13,PGM1,VAMP3,CLSTN1,TFAP2C,RNF113A,SNAPC2,H2AFV,MAPK8IP1,TJP3,FGFR2,HTT,PRCP,SPINT2,SPAG7,PIAS2,SFMBT1,AURKA |
| 3.066e-02 | -3.48 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 187 | 37 | 17758 | 2588 |
PAX6,FAF2,MPZL1,SEC61G,ADO,ARL4C,MORF4L2,OAT,SLC20A1,KTN1,LBR,PDIA4,CAPN2,TFAP4,TIMP1,MDFIC,BTBD3,TIPARP,SPRY2,LAMP3,CYP1B1,PGM1,ZC3H11A,PTPN9,PLAUR,DCHS1,TFAP2C,H2AFV,IL1R1,BTG1,PLOD2,HNRNPH2,SLC9A6,P4HA2,MAOA,ATP6V1C1,SRSF9 |
| 3.066e-02 | -3.48 | GSE13306_RA_VS_UNTREATED_TCONV_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_TCONV_UP | 187 | 37 | 17758 | 2588 |
OTUD5,LAMP1,BMF,NF2,IGFBP6,ATP8A1,CD82,C1orf198,IL27RA,NENF,ADCK5,PHLDA1,CDK14,LRRC45,NOV,KCNK5,CCDC82,PXMP4,GM2A,SMC4,CYP26B1,TBC1D8B,BCL9,PLEKHA7,PRKAR2B,NPHP3,SAV1,ARF4,SLC44A3,TMEM50B,COL13A1,CSF1,MPP2,IRF7,TANC2,LTA4H,PRR15 |
| 3.066e-02 | -3.48 | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 187 | 37 | 17758 | 2588 |
CCNC,LZTFL1,ARHGEF3,ZNF395,DHPS,SEC61G,MCCC1,ETNK1,PSMD7,CYB561,NENF,ECI1,LGALS3BP,ZNF432,PSMD1,ADD3,WDR44,ADCK2,DUSP10,RPN2,ETHE1,TRAM1,SOD1,GCLC,CDYL,DBR1,EPHA1,FANCE,NPDC1,TXK,CDCA4,LRIG1,CLIP4,AKIP1,CD81,USP16,DOCK9 |
| 3.066e-02 | -3.48 | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN | 187 | 37 | 17758 | 2588 |
INPP5D,HLA-F,SELL,UBE2Z,BLCAP,NOTCH2,SNN,MAP1LC3B,EXT2,AIP,DENND2D,SLC25A36,RNF220,SP100,CNTRL,TMEM62,PAK2,AIM1,FBXL14,PIK3CD,PIKFYVE,SYPL1,TGIF1,RIPK2,IFITM3,CYFIP2,NDRG3,STK17B,LCP1,CD83,ARHGAP24,FYN,BANK1,DCK,NMI,SPAG7,SLC25A38 |
| 3.066e-02 | -3.48 | GSE27786_LSK_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_LSK_VS_NEUTROPHIL_UP | 187 | 37 | 17758 | 2588 |
MRPL44,ST14,CNOT8,SLC25A13,POMGNT1,NUDT12,IFT27,PSIP1,CAPN2,TTC21B,SESN3,RNF220,SETDB2,PAPSS1,RCAN3,DLG3,C12orf75,P2RX4,PLEKHA6,STAU2,CBX6,CCBL2,FAM133B,LRRC1,TRUB1,C3orf58,VCP,ATP13A2,GNAS,PPP2R4,HAGHL,TRIM45,CSGALNACT1,CSTF2,ALG2,MLKL,HOOK1 |
| 3.066e-02 | -3.48 | GSE15767_MED_VS_SCS_MAC_LN_DN | MSigDB lists | GSE15767_MED_VS_SCS_MAC_LN_DN | 187 | 37 | 17758 | 2588 |
SIGIRR,FARP1,FAM92A1,TRIM24,IBTK,DAP,DNAJB2,CD82,IL27RA,TRIB2,SEPT4,ETS1,IL18R1,PSIP1,SS18,SETDB2,FAM160A2,PLEKHF1,MAPK11,ARNT2,TMEM64,DLG3,FAH,ADAMTS2,KIAA0040,MBNL3,ITPR3,SP4,CNOT2,PLCG1,HLF,FASTKD1,SIPA1L1,NDFIP1,RARG,CBX7,FAM134B |
| 3.066e-02 | -3.48 | GSE17721_LPS_VS_CPG_2H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_CPG_2H_BMDM_DN | 187 | 37 | 17758 | 2588 |
TTC8,ARHGEF3,P2RX7,NOTUM,RAB6A,SEPT4,SDC1,EFNB1,CHST2,KIAA1147,CD109,CXCL16,IL6ST,PPP4R1,COL6A1,SMO,POLL,CD70,NDUFA12,NAGA,FOPNL,ERP44,AKR1E2,ZBTB7B,FUCA1,RGS9,COL13A1,SHROOM3,DNM1L,ATXN7L3,WIPI1,SPINT2,NR4A3,ICOSLG,TRPC3,PSMC1,CD33 |
| 3.066e-02 | -3.48 | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN | MSigDB lists | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN | 187 | 37 | 17758 | 2588 |
PLA2G4A,PARP12,TRIP10,TRIM5,PSME2,MCTP2,FAM198B,STIL,NFAT5,RASSF8,APOBEC3B,METTL7A,POF1B,RNASEH2A,OAS3,DLG3,MAST4,TMX1,RHOA,PLSCR1,PRSS23,KIAA0040,USP18,SNTB2,TEP1,EAF2,PTGS2,PTPRJ,INSR,RBL1,MYLK,STAT1,SHOX2,UBE2C,IFI6,RTN3,OCLN |
| 3.066e-02 | -3.48 | GSE360_DC_VS_MAC_L_MAJOR_UP | MSigDB lists | GSE360_DC_VS_MAC_L_MAJOR_UP | 187 | 37 | 17758 | 2588 |
EXPH5,ANXA3,MTM1,CDK17,FARP1,PSMD7,HDAC6,KTN1,DNPEP,PDCD10,SRPX,CTNNB1,PFKL,FUT1,TRIM3,CDKN1B,CLDN4,MARCH2,MINPP1,LOXL1,TIAM1,STK35,PRODH,PTPN18,PRSS23,COG2,HTATIP2,KCTD20,SLC11A2,MSL1,PDLIM3,PGRMC1,HDAC1,NXPH4,TLE1,EIF4EBP2,PCSK5 |
| 3.074e-02 | -3.48 | APOBEC/CMP_deaminase_Zn-bd | interpro domains | IPR016192 | 13 | 5 | 18293 | 2672 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G,CDA |
| 3.074e-02 | -3.48 | CRAL/TRIO_N_dom | interpro domains | IPR011074 | 13 | 5 | 18293 | 2672 |
MOSPD2,SEC14L4,TTPA,PTPN9,SEC14L2 |
| 3.074e-02 | -3.48 | FERM-adjacent | interpro domains | IPR014847 | 13 | 5 | 18293 | 2672 |
EPB41L5,EPB41L4B,FARP1,EPB41L4A,FARP2 |
| 3.074e-02 | -3.48 | AcylCoA_DH/ox_N | interpro domains | IPR013786 | 13 | 5 | 18293 | 2672 |
ACADM,ACOX2,ACAD8,ACADSB,ACAD10 |
| 3.077e-02 | -3.48 | GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN | MSigDB lists | GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN | 9 | 4 | 17758 | 2588 |
NR4A2,FAM46C,FOSB,DUSP1 |
| 3.077e-02 | -3.48 | BENPORATH_ES_CORE_NINE | MSigDB lists | BENPORATH_ES_CORE_NINE | 9 | 4 | 17758 | 2588 |
NFE2L3,KLF5,HMGA1,MYBL2 |
| 3.077e-02 | -3.48 | ZHU_SKIL_TARGETS_DN | MSigDB lists | ZHU_SKIL_TARGETS_DN | 9 | 4 | 17758 | 2588 |
CCNE2,CDKN2C,TGFBR3,CCNA2 |
| 3.077e-02 | -3.48 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | MSigDB lists | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | 9 | 4 | 17758 | 2588 |
PITPNA,PLCG1,NTN1,TRPC3 |
| 3.077e-02 | -3.48 | PYEON_HPV_POSITIVE_TUMORS_DN | MSigDB lists | PYEON_HPV_POSITIVE_TUMORS_DN | 9 | 4 | 17758 | 2588 |
FAM89A,CCND1,CTTN,KLK10 |
| 3.077e-02 | -3.48 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | MSigDB lists | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | 9 | 4 | 17758 | 2588 |
WEE1,CCNB1,CDC25C,CDK1 |
| 3.077e-02 | -3.48 | SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_UP | MSigDB lists | SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_UP | 9 | 4 | 17758 | 2588 |
GAS2L1,JAG2,LTBP2,TP53 |
| 3.083e-02 | -3.48 | DENN | smart domains | SM00799 | 16 | 6 | 9131 | 1455 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 3.083e-02 | -3.48 | dDENN | smart domains | SM00801 | 16 | 6 | 9131 | 1455 |
ST5,SBF1,DENND2D,DENND1B,MADD,DENND5B |
| 3.087e-02 | -3.48 | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDM_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDM_UP | 193 | 38 | 17758 | 2588 |
CASP3,IL15RA,HLA-E,SDC4,OSGIN2,NES,SLC1A3,CRABP2,FAM46C,SLC9A3R2,SAC3D1,CKAP5,ARHGEF10L,CDKN2C,CPNE2,ZYX,CAPG,POF1B,AKR1B1,H2AFY,RTKN2,TINAGL1,ECE1,ETV4,PCDH1,LITAF,HTATIP2,STMN3,PDK3,EPHA1,ALCAM,DPYSL3,CNTNAP1,CACHD1,PTGS2,GPRC5B,CD81,GAB1 |
| 3.087e-02 | -3.48 | PENG_RAPAMYCIN_RESPONSE_UP | MSigDB lists | PENG_RAPAMYCIN_RESPONSE_UP | 193 | 38 | 17758 | 2588 |
TBC1D1,HLA-F,NDC80,TP53,GMPR,AES,RASGRP3,H1FX,TOP2A,TRANK1,CD22,BCL6,UBE2J1,SORL1,HMGCL,IFIT1,CTTN,ETHE1,CTDSP2,HMMR,OPLAH,QSOX1,PTPN18,ALDH2,DRAP1,PTPRH,BNIP3L,HMG20B,CD40,RNF19B,RNPEP,FUCA1,PPP2R5A,JAK1,PLXND1,CBX5,USF2,TMEM131 |
| 3.087e-02 | -3.48 | GSE2826_WT_VS_XID_BCELL_UP | MSigDB lists | GSE2826_WT_VS_XID_BCELL_UP | 193 | 38 | 17758 | 2588 |
LMO7,RECQL,NDRG1,DGKA,ETNK1,CDIPT,DHRS3,CMTM6,SIPA1L2,CD9,RNASEH2A,SMYD5,HSPA2,NCOA2,KDELR1,EPHX1,B3GNT2,PLSCR1,MPP1,RC3H2,CDC20,SPA17,NKAIN1,AURKB,BCL2L13,GTF2A2,CDK1,PRIM1,CD83,PTPRJ,CASP7,FAAH,TWSG1,NR4A3,HDAC1,RAP1GAP,MIIP,KLF7 |
| 3.087e-02 | -3.48 | GSE17721_0.5H_VS_8H_PAM3CSK4_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_8H_PAM3CSK4_BMDM_UP | 193 | 38 | 17758 | 2588 |
MRPS9,HSP90B1,PAPSS2,HLA-E,DAP,INPP5D,ERCC6L,AES,ZNF219,TSEN34,RABGGTA,ZYX,BDH1,GYS1,PLEKHF1,PPP1CA,MARCH2,NPTXR,RAG1,TRAM1,TIAM1,METAP2,ERMP1,PTPN18,TIMP2,TNS1,SESN1,RASA1,GINS4,SCARB2,PPP2R4,MAP3K11,RBM43,RAP1GAP,SERPINB1,PRR15,TOB1,ATMIN |
| 3.087e-02 | -3.48 | GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDM_DN | 193 | 38 | 17758 | 2588 |
ELK4,GALK1,ACVR1,TRIM2,PARP12,UPF3B,ELOVL7,MMADHC,LTBP3,DNAJB9,RNF128,KCNN4,IL6ST,DDHD2,RP2,DLG3,PTPRE,IL10RB,TMEM9,CRTAP,SUN2,SYP,ARFRP1,ERBB2IP,PRRC1,PNKD,TP53INP2,ARHGAP35,GDE1,RBL1,KBTBD2,NR4A3,EIF4EBP2,ZMIZ1,SLC25A30,E2F8,CPPED1,STARD3NL |
| 3.095e-02 | -3.48 | endocytic vesicle | cellular component | GO:0030139 | 251 | 48 | 17570 | 2579 |
LAMP1,UNC93B1,ANXA3,GOLIM4,HSP90B1,HLA-E,HLA-F,RAB23,PICK1,HLA-A,SH3KBP1,KIF5B,CALR,RAC2,ATP6V0B,AP1M2,OCRL,SMO,DNM2,CD9,DAB2IP,RAB20,HLA-C,WNT3A,FLOT2,SYK,CAMK2G,DVL2,GPR161,CLCN3,VPS11,FZD4,RAPGEF2,RAB38,EGFR,HLA-B,LDLRAP1,RAB11FIP1,RAB31,DYSF,PIK3C2B,ITGAV,PLD1,FZD5,ARF6,ABCA1,ANXA11,OCLN |
| 3.096e-02 | -3.48 | cellular response to lipid | biological process | GO:0071396 | 366 | 68 | 16441 | 2455 |
TRIM24,IL15,THRA,RET,IL18,CCNB1,SMO,DAB2IP,PDE4D,OSBPL7,NR2C1,THRB,RIPK2,AKT1,FZD4,CASP9,CD40,FZD7,ATP1A1,CDK19,AXL,TBX1,PTK7,STAT1,NR3C2,ABCA1,NR2C2,PRKAA2,NKX3-1,PLSCR4,SERPINB9,PRKAA1,SOX9,GSTP1,ICAM1,TFAP4,CXCL16,IRAK1,BMP7,KLF9,PIM1,WNT3A,GFI1,PAQR7,WNT10B,NR3C1,NR4A1,PPARA,LITAF,YES1,PDK3,ELK1,EGFR,GPLD1,GNAS,FECH,NCOA3,NR1D2,NFKBIA,DGAT2,NR4A3,E2F1,NR4A2,GPER1,OSR1,CMPK2,RARG,PHC1 |
| 3.098e-02 | -3.47 | ACATTCC,MIR-1,MIR-206 | MSigDB lists | ACATTCC,MIR-1,MIR-206 | 283 | 53 | 17758 | 2588 |
GAS2L1,SPRED1,TRIM2,TMEM55B,BLCAP,SLC7A2,FAM91A1,GRK6,ETS1,KTN1,CDK14,SS18,TGFBR3,ACAP2,PDCD10,FRAS1,RRBP1,SLC44A1,FOSB,TNPO2,TAGLN2,SLC39A10,CITED2,OSBPL7,DGKG,OLFML2A,CLCN3,BAG4,KCNIP3,MMD,RNF165,C2orf69,FNDC3A,CBL,PDIK1L,ANKRD29,RASA1,BSDC1,FZD7,PIAS3,NCOA3,TIMP3,PHLPP2,CORO1C,MYLK,NR4A2,TMOD2,RCAN2,HS3ST3B1,ZBTB6,MAL2,SRSF9,DMPK |
| 3.099e-02 | -3.47 | ATGTTTC,MIR-494 | MSigDB lists | ATGTTTC,MIR-494 | 152 | 31 | 17758 | 2588 |
TGIF1,PCOLCE,MMD,NF2,GRIK2,TACC1,FOXJ2,SYNE2,ELOVL3,EIF5A2,EGR3,GALNT7,MORF4L2,SP4,SSX2IP,DPYSL3,IRF2BPL,PITX2,ANKS1B,ZNRF2,WDR44,TACC2,FGFR2,PTER,FUT8,CKS1B,ZC3H12B,DMWD,MYLIP,ARNT,TMED2 |
| 3.099e-02 | -3.47 | regulation of cell junction assembly | biological process | GO:1901888 | 66 | 16 | 16441 | 2455 |
EPB41L5,FMN1,DMTN,RAPGEF2,SDC4,FLOT1,PKP2,PRKACA,TSC1,PTPRJ,PTEN,ACVRL1,CORO1C,EFNA5,FZD5,COL16A1 |
| 3.099e-02 | -3.47 | regulation of dendrite morphogenesis | biological process | GO:0048814 | 66 | 16 | 16441 | 2455 |
CIT,RAPGEF2,EPHA4,GRIN1,ILK,CDK5R1,CDKL5,SEMA4D,PTEN,KNDC1,BHLHB9,SIPA1L1,EFNA1,ITPKA,LZTS1,NGEF |
| 3.101e-02 | -3.47 | PDGF/VEGF_dom | interpro domains | IPR000072 | 9 | 4 | 18293 | 2672 |
PGF,PDGFA,PDGFC,PDGFB |
| 3.102e-02 | -3.47 | sarcoma | COSMIC cancer mutations | sarcoma | 57 | 14 | 17775 | 2585 |
GNAS,CDKN2C,RB1,SS18,CTNNB1,AKT1,PTEN,RET,PIK3CA,TP53,ERBB2,IDH1,FLT3,EGFR |
| 3.102e-02 | -3.47 | skin-forearm-malignant_melanoma | COSMIC cancer mutations | skin-forearm-malignant_melanoma | 57 | 14 | 17775 | 2585 |
EPHA10,TNS4,PTPRJ,CTNNB1,AKT1,PTK7,PTPRH,PIK3R1,PIK3CA,TP53,TNS1,IDH1,PTPRE,EGFR |
| 3.105e-02 | -3.47 | nucleus | cellular component | GO:0005634 | 6737 | 1032 | 17570 | 2579 |
HECA,IBTK,CCNO,TGOLN2,ISOC2,DPP8,ZNF275,NPM2,CDKN2C,UBE2T,DNM2,CRY2,PPP1CA,WBP4,TIPARP,CPE,UXT,TFAP2C,PNKD,GINS4,PIAS3,PLCG1,MID1IP1,CELF5,NOD2,HDAC1,RNASEL,HSPB1,ANXA11,NXT2,GGA1,MTL5,FAM21C,TFAP4,FLII,RAC2,ZCCHC17,MEGF8,ATP5H,FBXO7,RANBP1,FBXL14,CADPS2,USP1,ZMYM1,MAPK7,NUP85,REC8,MAPKAPK3,PYM1,SHARPIN,FHL2,KIF20B,ELK1,PSMA4,IL1R1,ETS2,S100A5,STK39,GDF11,CFAP20,CBX5,NUP58,RUSC1,DMPK,PTTG1,MAPK4,MGST2,MVB12B,MOCS1,APPBP2,RBM23,TAX1BP3,MYT1,SNX10,ETV4,MX1,AGPS,VPS4B,HTATIP2,XRCC6BP1,GTF2A2,TRIM7,ZNF618,EBF2,NFIX,CCNB3,CDK19,MAPK12,HSP90B1,GCAT,DCAF7,ESRP1,HABP4,FLOT1,ZNF219,HDGFRP2,NFAT5,BEX2,CTNNBIP1,ZFX,FAM20B,CST3,BAX,RAG1,MED22,PARP9,ACBD5,PLSCR1,TACC1,PIK3R1,DUSP23,NUB1,UBE2A,PGBD1,RAB3IP,C4orf27,RAB11FIP2,PPM1H,NR4A3,SSNA1,CMPK2,OSR1,SRSF9,ACOT7,PHC1,EPAS1,CNOT8,ARFGEF1,LMCD1,NDRG2,NENF,SLC9A3R2,FANCI,TFAP2E,CPNE2,RPS6KA2,NUP210,CTNNB1,PSMC2,MITF,SLC44A1,PASK,SMAGP,PLK1,THRB,KCNIP3,PTPN18,STAU2,CBX6,NFE2L1,EAF2,SESN1,KDM4D,KLF12,ZNF367,HOXA9,KLF11,KPNA2,TC2N,RRAGD,RUNX2,PARP12,HJURP,LGALS3,DNAJB2,PSMD7,SORBS3,HES2,AHCY,PIM1,USP31,ZNF320,EMC2,STRADB,SCRIB,ZSCAN12,BCL2L13,PRX,CDK5R1,FOXD2,PHLPP2,NLRC5,ZDHHC7,AKIP1,CCNB2,CDAN1,USP43,RAD21,HOXB7,CTDSPL,TP53,P2RX7,RHPN2,BAHD1,PCBP1,EMP2,IER3,TTC21B,KMT5C,TACC2,BCL6,PLK4,NOTCH3,OAS3,CTDSP2,AKT1,SERTAD3,DAG1,CFAP36,PTGS2,ZNF628,IDE,RBL1,STK38,CHMP4B,XRCC3,IRF7,CTDSP1,BIN1,ZMAT1,CMAS,PINK1,DYRK3,CPEB4,TAB3,CTSB,MCTP2,CDCA8,ERCC6L,ERI2,GTF3A,HMGN3,LBR,AIP,PARM1,DNAJB9,H1FX,FOXP2,GTF2F2,FAM63A,TFAP2A,SGK1,TRIM21,ALDH7A1,SYK,ATP2B1,DUSP1,WBP5,NFE2L3,P2RX4,HES1,RHOA,HMGN5,PRICKLE1,DPP9,MAML2,GGH,BCL10,DDX23,CNOT2,NEIL3,NIPSNAP3A,FGF18,E2F1,SH3BGRL2,PTGES,HIPK3,ZBTB33,PKIA,TXN,PNISR,SSH1,TSC22D3,CUL1,PSME1,CAMK1D,SEPT4,PAK6,HELZ2,ZNF823,OSBPL3,PALD1,FOSB,POLL,IRF2,TACSTD2,HYLS1,ZBTB18,CDYL,BNIP3L,LDB2,PRIM1,PPP2R4,PRDM5,NFKBIZ,CCDC97,RECQL,CDKN1C,TBC1D1,THEMIS2,PRKAA1,AKAP17A,TXNDC9,HERC6,APBA1,PSIP1,SH3RF2,CALR,C9orf69,BHLHE41,MSH2,DLX4,ZNF117,TRAK2,GID8,PRSS23,CALM1,WHSC1,JADE2,NFIB,TJP3,FAM64A,WDR19,AGBL5,PIAS2,APPL2,SFMBT1,CABIN1,ZBTB34,PER3,IFIH1,SPRED1,FOXO6,TCF25,DLGAP5,THRA,NDRG1,CCDC110,FTH1,BCL2L1,EPM2A,APOBEC3B,CCNA2,RNASEH2A,SULT2B1,MED30,MSANTD4,FOXJ2,CYB5R2,DRAP1,PANK1,UTRN,CLSTN1,RAD17,PYGO1,PKMYT1,CBL,ITPR3,ATP10D,CEP162,ZMPSTE24,NGFRAP1,TRIOBP,CBX7,DEPDC1,CENPI,CBLL1,PBX3,SPDL1,EFNB1,WWP2,SCML1,E2F7,GNB5,CITED2,MSH6,PDGFC,TGIF1,ZWINT,PAPD7,ZC3H11A,TCFL5,ZKSCAN2,DIAPH2,FOS,CPTP,CRTC2,TIMP3,FGFR2,TBX18,RYK,RABL6,WDR62,ESPL1,DEF6,CCNC,CRYM,UBE2Q1,MPP5,COMMD5,TRIM68,HSF2,CDKL5,SIVA1,ASH2L,BTBD3,SP5,STK35,CERS2,CXXC5,CENPA,LAP3,ASXL1,ITCH,USP18,GPRC5B,HPSE,SH3GLB2,ZNF165,SP6,NRGN,NR2C2,ZNF395,PPP1R12A,ETV5,ABCG2,CALM3,PM20D2,DUSP5,QSOX2,OCRL,PRKCI,SRP54,BRAT1,ZRANB1,ETV7,MDFI,ELK3,KIAA1109,NUBP1,PDIK1L,RANBP9,SOX13,UAP1,SH3BP4,SPAG7,DCUN1D1,DONSON,CTSA,TOB1,RARG,DRD1,CCNE2,LMO7,SORBS1,PAX6,FAM214B,HDAC11,OSR2,PHLDA1,MXD1,SAP130,ZNF687,KIF14,ZBTB49,NFKB2,ETHE1,UPF3A,SEPHS1,CHP1,CDC25C,FANCE,ARHGAP35,JADE1,HSF4,STAT6,TLE1,PTBP3,MAD2L1BP,GLIS3,SH3D19,SHPRH,SERPINB9,INTS8,TRIB2,NTAN1,SBF1,HMGXB4,HDAC9,TOP2A,CARD8,TAF1B,LLGL2,MYCL,TOX2,ARVCF,H2AFY,RBMS2,DCAF6,CFAP46,RC3H2,SYBU,RGCC,RUNX3,TCEAL8,FOXL1,LEMD2,CTSL,CASP7,SWAP70,TRIM69,CTSV,ARRB1,UACA,ZMIZ1,AHR,ABCG1,ACACB,IL15RA,ADD1,TRIM24,TRIM5,MRPS15,SMARCAL1,XIAP,DHX8,SYTL4,MORF4L2,BARD1,PHF1,CALM2,TP73,ZYX,WEE1,RGS12,PSMD1,CABP1,KLF3,RDH14,TUBG1,MANF,APOBEC3G,SMARCA2,TNIP1,SH3BGRL,SERTAD4,SPRTN,RNF11,LOXL2,TRIM47,CAMK2N2,WDR11,ANKRD6,LIMK1,SERPINB6,E2F8,HOXC13,ALDH6A1,FAM169A,NUAK1,SOX9,LMNA,ELF3,RAVER2,WDFY1,DNPEP,PRICKLE4,ZIC5,NEK2,C9orf72,UFD1L,KIF20A,SALL4,STAT4,MYBL2,SRSF5,ILK,TP53INP2,DCP2,RHOB,DHX32,STK17A,NCOA3,HTT,TEX30,SETD3,ITPR1,AURKA,ALG2,ZNF502,CSRP2,RPS6KA3,EGLN1,GRHL2,TUBB4B,ACTR8,RGS20,WDTC1,ETNK1,TESK2,PKP2,NUF2,PRKACA,ZNF385B,CCND1,SP100,DACT1,ARL4D,CDKN2D,RNF169,SSH3,NRBF2,SYNE2,PLEKHO1,NUSAP1,CDCA2,WWTR1,PDXK,RGS14,GEN1,ARNT,TAOK2,NKX3-1,RBM24,PARP14,PDIA3,GMCL1,NUCB2,TMA16,PKN1,GSTP1,ETS1,HOXB2,NEO1,CAPN2,DTX3L,ADD3,ANK1,IRAK1,ANKS1B,TMBIM6,ECI2,PLEKHF1,MAPK11,ZNF230,WWP1,TMX1,S100A6,POU6F1,FMN1,BCL9,EIF5A2,DBR1,PLEKHA7,TXK,PITX2,BTG1,NR1D2,ATXN7L3,ZFP30,FHL1,HMGA1,CENPE,NUP37,SHOX2,USF2,FOXA1,UNKL,CUL4B,NDC80,SUDS3,HDAC6,NUP62CL,PCNA,ELF5,DUSP10,MYBL1,S100A13,DDX59,ZNF462,PCGF5,ING1,CITED4,HN1L,EZR,KLK6,PRKRA,ANLN,ZBTB7B,CDK1,RHEB,VCP,IRX3,OPTN,MFAP3L,MSL1,CDCA4,MAP2,P4HA2,PIK3C2B,CTNND1,MAFF,PRKAA2,UBASH3B,RACGAP1,SSX2IP,RB1,DAZAP1,GATA2,CMTR2,PAK2,MDFIC,PSMA5,PCBP3,SPATA13,TCF7,SMN1,G2E3,EPN3,MAPKAPK2,H1F0,TMEM120A,CTBP1,RNF146,UGP2,UPF3B,NF2,FOXM1,ERBB2,ZNF28,CCNL1,LPIN3,CDK14,RAD23A,PER2,LHX6,EGLN3,DVL2,CTH,SIRT1,CPD,MBP,TCEB2,FIGNL1,S100A4,CDC20,MYPOP,PSMD3,ZBTB6,RPL22,LTA4H,AIFM3,ZNF701,CNEP1R1,ZC3HC1,GSDMD,GOLIM4,PACSIN2,MACC1,BLVRB,SWI5,PSMD10,NKRF,CRABP2,GBX2,MAGEE1,BUB1,KLF9,HEXIM2,TLE6,CAMK2G,PSMB4,NR3C1,PPARA,LITAF,CARD19,TRIM35,FXR2,AKAP3,BCAR1,MAPK8IP1,PRDX4,ZNF214,NMI,CDCA7L,PGRMC1,PPP2R3C,ACADM,UBE2C,DIS3L,SUN1,FAM129B,GATA3,PLXNA1,CCNB1,CENPN,SESN3,RGS3,ZFP36,LOC81691,PBK,CASP9,AURKB,PIF1,SAV1,CCNF,SLC25A5,AHRR,HLF,RBM47,SLC25A4,AREG,TBX1,GNPTAB,FAM110C,TMEM8B,KLF2,DGKQ,CALB2,KIF23,NOTCH2,BMP2K,KIAA1161,MECOM,SNX18,NECAB3,BDH1,SORL1,EEF1D,EPB41L5,DDB2,ZNF84,B9D2,AMER1,VEZT,PKM,KDM3A,FAS,DGKH,PRKAG2,SERTAD2,DCK,NAB2,TCEAL4,NR4A2,NRBP1,IRF1,ELK4,CEP70,TRIP10,S100A11,CAST,SUZ12,RPS6KA1,IRX4,EGR3,NUDT12,MNS1,APLP2,CYHR1,ZNF75D,CDKN1B,TNPO2,NR2C1,GPX4,CDKN2AIP,TMEM43,LYRM1,TEP1,SLC11A2,PRKCQ,H2AFV,ZNF469,SP4,PRDM11,NIN,FYN,ZNF641,PPP2R5A,JAK1,CFAP45,STK26,STAT1,PPP1CB,NRG1,KLF5,NR3C2,ATMIN,MRPS9,NUDT6,JRKL,ARL4C,CCNJL,APOBEC3H,SPR,SIX4,TEAD3,AKIRIN1,FAM111A,PHF7,PPP1R10,PTEN,PRC1,ERCC2,MAP3K7,CNOT6L,GFI1,SPRY2,NCOA2,SMC4,CASK,SHMT1,TEF,PARP4,RGS9,NUCB1,CSTF2,GPER1,NCAPG2,CPEB2,JARID2,USP16,CASP3,EMX1,CAMKK1,CPT2,UBE2Z,TAF6L,KIF2C,TSEN34,MAGOHB,ZCCHC12,GRHL1,PHTF1,CAPG,DLG1,ANKRD12,AKR1B1,KIF22,SUN3,ARNT2,NFU1,TECR,PTPRE,TDP1,SOD1,TRIM8,ASCL5,SYNE3,FOPNL,RNF165,STK17B,SEC14L2,NEIL1,ZNF114,TRIM45,PPP2R5D,PSMC1,PIFO,PHLPP1,ZNF432,EBF4,ZNF692,RFX5,KNTC1,LRIF1,HP1BP3,OXR1,FBXO8,HMG20B,EGFR,GNAS,ONECUT1,NUDT16,UTP14C,CDCA5,NFKBIA,PAPD5,ALPK3,KLF7,SPC25,IL15,PSME2,MORC4,PATL2,LRRC45,SS18,SETDB2,RPN2,TWIST1,GOT1,HSPA2,ZNF525,BAG4,TAF5,OSTM1,ERBB2IP,SNAPC2,DUSP4,BHLHB9,PEX2,OVOL1,AKNA,SGOL1,CBX4,SORT1,MIER3,AES,ZNF212,IRF2BPL,MDM1,BRD7,CKS1B,MXD3,SUN2,CENPC,NR4A1,ASPM,MBNL3,POLD3,SPAG1,C2orf70,HNRNPH2,DHRS2,UBE2D2,TADA2B,OTUB2,HOXB13,GEM,SOX8,ZNF596 |
| 3.109e-02 | -3.47 | CAHOY_ASTROGLIAL | MSigDB lists | CAHOY_ASTROGLIAL | 95 | 21 | 17758 | 2588 |
PSRC1,FBLN5,PRSS23,LGALS3,PQLC3,ATP8A1,MORC4,EMP3,PKP2,LOXL2,LPIN3,FAS,CD109,TIMP1,ACTA2,DYSF,TNFRSF12A,TMEM37,CTTN,LTBP2,SEMA3B |
| 3.111e-02 | -3.47 | ZIC3 (Zic family member 3) | protein interactions | 7547 | 5 | 3 | 16036 | 2547 |
TWIST1,CTNNB1,TP53 |
| 3.111e-02 | -3.47 | IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker)) | protein interactions | 3502 | 5 | 3 | 16036 | 2547 |
ALDH2,CA8,EGFR |
| 3.111e-02 | -3.47 | TRPC7 (transient receptor potential cation channel, subfamily C, member 7) | protein interactions | 57113 | 5 | 3 | 16036 | 2547 |
MX1,ITPR3,TRPC3 |
| 3.111e-02 | -3.47 | ZNF507 (zinc finger protein 507) | protein interactions | 22847 | 5 | 3 | 16036 | 2547 |
SUN1,NAAA,LHX6 |
| 3.111e-02 | -3.47 | LRRC29 (leucine rich repeat containing 29) | protein interactions | 26231 | 5 | 3 | 16036 | 2547 |
HOOK1,STIL,ADAMTSL4 |
| 3.111e-02 | -3.47 | UNC5C (unc-5 netrin receptor C) | protein interactions | 8633 | 5 | 3 | 16036 | 2547 |
NTN1,DAP,DAPK1 |
| 3.111e-02 | -3.47 | DOK6 (docking protein 6) | protein interactions | 220164 | 5 | 3 | 16036 | 2547 |
ERBB2,RET,EGFR |
| 3.111e-02 | -3.47 | ATP5G1 (ATP synthase, H+ transporting, mitochondrial Fo complex subunit C1 (subunit 9)) | protein interactions | 516 | 5 | 3 | 16036 | 2547 |
BTN3A2,B4GALT3,TRIM69 |
| 3.111e-02 | -3.47 | MRC2 (mannose receptor, C type 2) | protein interactions | 9902 | 5 | 3 | 16036 | 2547 |
FBXO6,LGALS3,LGALS8 |
| 3.111e-02 | -3.47 | ELOVL4 (ELOVL fatty acid elongase 4) | protein interactions | 6785 | 5 | 3 | 16036 | 2547 |
LYPD3,LYPD6,CERS2 |
| 3.111e-02 | -3.47 | CDH24 (cadherin 24, type 2) | protein interactions | 64403 | 5 | 3 | 16036 | 2547 |
CTNND1,CTNNB1,PPP1R16A |
| 3.111e-02 | -3.47 | SPNS1 (spinster homolog 1 (Drosophila)) | protein interactions | 83985 | 5 | 3 | 16036 | 2547 |
UNC93B1,BCL2L1,NLRX1 |
| 3.111e-02 | -3.47 | NUDT19 (nudix hydrolase 19) | protein interactions | 390916 | 5 | 3 | 16036 | 2547 |
NPC2,PEX5,SLC9A3R2 |
| 3.111e-02 | -3.47 | RNF135 (ring finger protein 135) | protein interactions | 84282 | 5 | 3 | 16036 | 2547 |
DDX58,CTNNAL1,UBE2D2 |
| 3.111e-02 | -3.47 | E7 (transforming protein) | protein interactions | 1489079 | 5 | 3 | 16036 | 2547 |
RB1,CCNA2,RBL1 |
| 3.111e-02 | -3.47 | Aif1l (allograft inflammatory factor 1-like) | protein interactions | 108897 | 5 | 3 | 16036 | 2547 |
AIF1L,PCBP1,PCBP3 |
| 3.111e-02 | -3.47 | OR10H3 (olfactory receptor, family 10, subfamily H, member 3) | protein interactions | 26532 | 5 | 3 | 16036 | 2547 |
LASP1,PAK2,CYB5A |
| 3.111e-02 | -3.47 | KMT2E (lysine (K)-specific methyltransferase 2E) | protein interactions | 55904 | 5 | 3 | 16036 | 2547 |
CUL1,CDK1,TP53 |
| 3.111e-02 | -3.47 | PSD3 (pleckstrin and Sec7 domain containing 3) | protein interactions | 23362 | 5 | 3 | 16036 | 2547 |
MX1,ARAP1,TP53 |
| 3.111e-02 | -3.47 | ASPHD2 (aspartate beta-hydroxylase domain containing 2) | protein interactions | 57168 | 5 | 3 | 16036 | 2547 |
B4GALT3,LYPD3,SPINT2 |
| 3.111e-02 | -3.47 | SNX33 (sorting nexin 33) | protein interactions | 257364 | 5 | 3 | 16036 | 2547 |
ADAM15,SNX9,PAK2 |
| 3.111e-02 | -3.47 | TMEM230 (transmembrane protein 230) | protein interactions | 29058 | 5 | 3 | 16036 | 2547 |
ARL4D,TMEM9,LMNA |
| 3.111e-02 | -3.47 | Sgol1 (shugoshin-like 1 (S. pombe)) | protein interactions | 72415 | 5 | 3 | 16036 | 2547 |
PPP2R5A,SGOL1,PPP2R5D |
| 3.111e-02 | -3.47 | GPLD1 (glycosylphosphatidylinositol specific phospholipase D1) | protein interactions | 2822 | 5 | 3 | 16036 | 2547 |
CD55,ALPP,GM2A |
| 3.111e-02 | -3.47 | ZFP1 (ZFP1 zinc finger protein) | protein interactions | 162239 | 5 | 3 | 16036 | 2547 |
SESN3,CBX5,SERTAD4 |
| 3.111e-02 | -3.47 | GJA5 (gap junction protein alpha 5) | protein interactions | 2702 | 5 | 3 | 16036 | 2547 |
MARK1,PRKACA,RIMS3 |
| 3.111e-02 | -3.47 | Sirt1 (sirtuin 1) | protein interactions | 93759 | 5 | 3 | 16036 | 2547 |
IRS2,DYRK3,TP53 |
| 3.111e-02 | -3.47 | CTRL (chymotrypsin-like) | protein interactions | 1506 | 5 | 3 | 16036 | 2547 |
PSME1,PSME2,PDIA5 |
| 3.111e-02 | -3.47 | Mprip (myosin phosphatase Rho interacting protein) | protein interactions | 26936 | 5 | 3 | 16036 | 2547 |
UACA,MPRIP,CDK1 |
| 3.111e-02 | -3.47 | CARS2 (cysteinyl-tRNA synthetase 2, mitochondrial (putative)) | protein interactions | 79587 | 5 | 3 | 16036 | 2547 |
PTEN,EGFR,RGCC |
| 3.111e-02 | -3.47 | KLK13 (kallikrein related peptidase 13) | protein interactions | 26085 | 5 | 3 | 16036 | 2547 |
SERPINB6,SERPINA1,SERPINE2 |
| 3.111e-02 | -3.47 | ROR1 (receptor tyrosine kinase-like orphan receptor 1) | protein interactions | 4919 | 5 | 3 | 16036 | 2547 |
TRIM21,TBC1D4,TBC1D1 |
| 3.111e-02 | -3.47 | FBXO10 (F-box protein 10) | protein interactions | 26267 | 5 | 3 | 16036 | 2547 |
CUL1,PVRL4,FAM219A |
| 3.114e-02 | -3.47 | positive regulation of protein kinase B signaling | biological process | GO:0051897 | 82 | 19 | 16441 | 2455 |
TXN,PINK1,BAG4,ARFGEF1,GATA3,TGFBR1,ILK,EGFR,KIAA1161,PDGFA,INSR,PTPRJ,IGF1R,HPSE,AXL,FAM110C,NRG1,MYDGF,SPRY2 |
| 3.114e-02 | -3.47 | nucleoplasm | cellular component | GO:0005654 | 2802 | 444 | 17570 | 2579 |
TXN,PNISR,SSH1,ADD1,IBTK,FAM129B,XIAP,SMARCAL1,CCNO,DHX8,CUL1,GATA3,TGOLN2,PSME1,MORF4L2,SYTL4,CCNB1,DPP8,SEPT4,BARD1,CENPN,PHF1,TP73,CALM2,WEE1,HELZ2,PSMD1,UBE2T,RGS3,POLL,IRF2,PPP1CA,ZBTB18,WBP4,SMARCA2,TNIP1,CDYL,SPRTN,TFAP2C,LOXL2,AURKB,GINS4,PRIM1,LIMK1,PPP2R4,FAM110C,HDAC1,ANXA11,NXT2,RECQL,ALDH6A1,GGA1,DGKQ,SOX9,AKAP17A,KIF23,NOTCH2,PSIP1,BMP2K,LMNA,SH3RF2,MECOM,FLII,DNPEP,SNX18,ATP5H,BDH1,MSH2,FBXL14,USP1,CADPS2,MAPK7,C9orf72,GID8,DDB2,UFD1L,KIF20A,SALL4,MAPKAPK3,STAT4,CALM1,PYM1,FHL2,MYBL2,WHSC1,VEZT,KIF20B,SRSF5,ELK1,ILK,TP53INP2,KDM3A,JADE2,PSMA4,DCP2,NCOA3,PRKAG2,ETS2,HTT,SETD3,WDR19,PIAS2,APPL2,SFMBT1,NR4A2,CABIN1,ZBTB34,GDF11,CFAP20,CBX5,NRBP1,RPS6KA3,IRF1,ELK4,SPRED1,CEP70,GRHL2,TRIP10,THRA,RPS6KA1,SUZ12,ETNK1,PKP2,TESK2,MAPK4,PRKACA,CCND1,CYHR1,CCNA2,SP100,DACT1,CDKN1B,RNASEH2A,CDKN2D,ETV4,MYT1,NR2C1,MED30,RNF169,CDKN2AIP,NRBF2,SYNE2,LYRM1,UTRN,HTATIP2,CDCA2,RAD17,PYGO1,PKMYT1,ITPR3,GTF2A2,ATP10D,SP4,CEP162,ZNF641,CCNB3,CFAP45,WWTR1,STAT1,PPP1CB,KLF5,PDXK,RGS14,GEN1,NR3C2,CBX7,ARNT,MAPK12,DEPDC1,GCAT,CENPI,DCAF7,ESRP1,HABP4,CBLL1,PKN1,ETS1,SPR,NFAT5,TEAD3,NEO1,CTNNBIP1,DTX3L,AKIRIN1,ZFX,ADD3,PHF7,ANKS1B,PTEN,PPP1R10,FAM20B,PRC1,ECI2,MAPK11,ERCC2,MAP3K7,RAG1,GFI1,MED22,NCOA2,MSH6,SMC4,PARP9,ACBD5,TGIF1,PAPD7,BCL9,FOS,CRTC2,FGFR2,RAB11FIP2,ATXN7L3,NR1D2,NR4A3,CSTF2,HMGA1,CMPK2,NUP37,NCAPG2,USF2,SRSF9,ACOT7,JARID2,PHC1,CCNC,CASP3,EPAS1,CPT2,CUL4B,SUDS3,ARFGEF1,LMCD1,NDRG2,UBE2Z,NENF,MPP5,TAF6L,HDAC6,TSEN34,FANCI,PCNA,RPS6KA2,CTNNB1,GRHL1,ZCCHC12,CDKL5,SIVA1,PSMC2,SLC44A1,CAPG,AKR1B1,ANKRD12,DUSP10,ASH2L,NFU1,SMAGP,PLK1,THRB,SOD1,CXXC5,TRIM8,CENPA,ING1,LAP3,CBX6,KLK6,EAF2,PRKRA,ANLN,ZBTB7B,CDK1,VCP,OPTN,KDM4D,NEIL1,MSL1,KLF12,HPSE,ZNF367,TRIM45,KPNA2,PSMC1,MAFF,PPP2R5D,NR2C2,PRKAA2,RUNX2,PPP1R12A,HJURP,ETV5,PSMD7,CALM3,RACGAP1,PM20D2,DUSP5,RB1,DAZAP1,GATA2,PAK2,SRP54,MDFIC,ZRANB1,ETV7,PSMA5,ELK3,SPATA13,HMG20B,SCRIB,TCF7,PDIK1L,SMN1,CDK5R1,SOX13,MAPKAPK2,EPN3,NUDT16,UAP1,H1F0,CDCA5,ZDHHC7,CTSA,AKIP1,CCNB2,CTBP1,RARG,RAD21,USP43,CCNE2,SORBS1,PAX6,UPF3B,HOXB7,FOXM1,IL15,PSME2,HDAC11,TP53,MORC4,RHPN2,CCNL1,BAHD1,PCBP1,PER2,SAP130,LRRC45,KMT5C,SETDB2,NOTCH3,OAS3,ETHE1,EGLN3,NFKB2,CTDSP2,UPF3A,SIRT1,TAF5,TCEB2,AKT1,CDC20,ERBB2IP,SNAPC2,DUSP4,FANCE,CDC25C,DAG1,JADE1,HSF4,IDE,RBL1,STAT6,STK38,PSMD3,PEX2,TLE1,XRCC3,IRF7,SGOL1,LTA4H,CBX4,CTDSP1,GLIS3,GSDMD,CMAS,GOLIM4,PACSIN2,TAB3,SH3D19,BLVRB,MCTP2,ERCC6L,PSMD10,GTF3A,HMGN3,INTS8,CRABP2,AIP,HDAC9,IRF2BPL,TOP2A,CARD8,TAF1B,LLGL2,TOX2,GTF2F2,TFAP2A,FAM63A,SGK1,CKS1B,H2AFY,BUB1,KLF9,HEXIM2,CAMK2G,HES1,PSMB4,CENPC,HMGN5,NR3C1,NR4A1,RC3H2,SYBU,LITAF,PPARA,MAML2,POLD3,SPAG1,DDX23,CASP7,TRIM69,NEIL3,HNRNPH2,NMI,E2F1,TADA2B,UBE2D2,ARRB1,SH3BGRL2,HOXB13,ZMIZ1,UBE2C,AHR,HIPK3,ZBTB33,ABCG1 |
| 3.116e-02 | -3.47 | atrial septum development | biological process | GO:0003283 | 17 | 6 | 16441 | 2455 |
WHSC1,NOTCH2,ACVR1,NPHP3,CYR61,SMO |
| 3.116e-02 | -3.47 | negative regulation of defense response to virus | biological process | GO:0050687 | 17 | 6 | 16441 | 2455 |
IFIT1,NLRX1,ITCH,MICB,TSPAN6,TRAF3IP1 |
| 3.116e-02 | -3.47 | purine nucleoside bisphosphate biosynthetic process | biological process | GO:0034033 | 17 | 6 | 16441 | 2455 |
ACACB,PAPSS2,SLC35B3,PAPSS1,PANK1,ACOT7 |
| 3.116e-02 | -3.47 | ribonucleoside bisphosphate biosynthetic process | biological process | GO:0034030 | 17 | 6 | 16441 | 2455 |
ACACB,PAPSS2,SLC35B3,PAPSS1,PANK1,ACOT7 |
| 3.116e-02 | -3.47 | dendritic spine organization | biological process | GO:0097061 | 17 | 6 | 16441 | 2455 |
CTTN,ITGA3,TANC1,ITPKA,PTEN,PICK1 |
| 3.116e-02 | -3.47 | amelogenesis | biological process | GO:0097186 | 17 | 6 | 16441 | 2455 |
CNNM4,FAM20C,STIM1,TBX1,ITGA6,PPARA |
| 3.116e-02 | -3.47 | branching involved in salivary gland morphogenesis | biological process | GO:0060445 | 17 | 6 | 16441 | 2455 |
PLXND1,PLXNA1,FGFR2,SEMA3A,BMP7,DAG1 |
| 3.116e-02 | -3.47 | metanephric nephron epithelium development | biological process | GO:0072243 | 17 | 6 | 16441 | 2455 |
PKD2,HES1,OSR1,SOX8,LGR4,SOX9 |
| 3.116e-02 | -3.47 | kidney mesenchyme development | biological process | GO:0072074 | 17 | 6 | 16441 | 2455 |
PKD2,OSR1,BMP7,SIX4,AMER1,STAT1 |
| 3.116e-02 | -3.47 | nucleoside bisphosphate biosynthetic process | biological process | GO:0033866 | 17 | 6 | 16441 | 2455 |
ACACB,PAPSS2,SLC35B3,PAPSS1,PANK1,ACOT7 |
| 3.116e-02 | -3.47 | metanephric tubule development | biological process | GO:0072170 | 17 | 6 | 16441 | 2455 |
PKD2,HES1,OSR1,SOX8,LGR4,SOX9 |
| 3.116e-02 | -3.47 | positive regulation of glycoprotein biosynthetic process | biological process | GO:0010560 | 17 | 6 | 16441 | 2455 |
SOAT1,PXYLP1,CTNNB1,IL15,ARFGEF1,CHP1 |
| 3.116e-02 | -3.47 | BENPORATH_MYC_MAX_TARGETS | MSigDB lists | BENPORATH_MYC_MAX_TARGETS | 752 | 128 | 17758 | 2588 |
LAMP1,TRIM24,HEBP1,HDAC6,BARD1,TSEN34,PCNA,RPS6KA2,ARL1,TUBG1,ASH2L,MANF,SOD1,ING1,UXT,CR2,ARFRP1,SAV1,PRKRA,CLCN2,RHEB,VCP,DPYSL3,PIAS3,GDE1,SH2D3C,MADD,PPP2R4,TMOD2,MAFF,DDX58,RECQL,PPP1R12A,PEX6,HLA-F,PSMD7,ASAH1,GNS,CALR,RAC2,VASP,FRY,MSH2,SRP54,USP1,RFX5,ACAD8,MAPK7,SLC12A2,PSMA5,MCCC2,DNAI1,NAGPA,PMPCB,KIF20A,KIF20B,SRSF5,PDK3,ILK,SPTLC2,NUBP1,ZDHHC3,RASA1,PTPRF,MMP15,PRPS2,MDH1,MAP3K5,CBX5,LZTFL1,SLC2A4,TP53,TESK2,FTH1,EPM2A,ARHGEF16,PPME1,CDKN1B,FLOT2,NAGA,HSPA2,CKS2,CLCN3,SEC61B,RIPK2,AGPS,SLC39A8,SP4,ZMPSTE24,STX10,RBL1,CORO1C,PSMD3,PPP1CB,LTA4H,NUDT6,HSP90B1,ENO2,JRKL,ARHGEF7,PSMD10,NFAT5,HLA-A,M6PR,SGPL1,PDCD10,CDK16,CTSC,H2AFY,TAGLN2,SYK,HMMR,SYPL1,GCLC,GGH,FXR2,KIF11,CNOT2,CCDC6,DBI,PLA2G15,SLC25A40,AMMECR1,FZD5,PLOD3,DEF6,TLL2,JARID2 |
| 3.118e-02 | -3.47 | ITSN1 (intersectin 1) | protein interactions | 6453 | 103 | 24 | 16036 | 2547 |
DLGAP1,PLK1,TRIM8,SCOC,DSTN,PIK3R1,CCNO,CBL,SPDL1,REPS1,SH3KBP1,GAREM2,PIK3AP1,RAB11FIP2,LMO4,SETD3,DNM2,AGFG2,PIK3C2B,RNASEH2A,PDE4D,ARF6,CLIP2,SPRY2 |
| 3.118e-02 | -3.47 | SPINT2 (serine peptidase inhibitor, Kunitz type, 2) | protein interactions | 10653 | 103 | 24 | 16036 | 2547 |
MOSPD2,CTSB,CDC20,ARFGEF1,TAF6L,PKMYT1,FNDC3A,ILK,SPTLC2,CMTM6,CKAP5,ASPHD2,CNTNAP1,PI4K2B,WDR44,OCRL,KIF14,ZDHHC13,TUBG1,EGFL7,SLC39A10,LRIF1,SLC27A3,EPHX1 |
| 3.119e-02 | -3.47 | KEGG_CHRONIC_MYELOID_LEUKEMIA | MSigDB lists | KEGG_CHRONIC_MYELOID_LEUKEMIA | 73 | 17 | 17758 | 2588 |
AKT1,PIK3R1,TP53,TGFBR1,BCL2L1,CBL,MECOM,CCND1,RB1,SHC3,NFKBIA,E2F1,PIK3CA,CDKN1B,HDAC1,PIK3CD,CTBP1 |
| 3.119e-02 | -3.47 | HOSHIDA_LIVER_CANCER_SURVIVAL_UP | MSigDB lists | HOSHIDA_LIVER_CANCER_SURVIVAL_UP | 73 | 17 | 17758 | 2588 |
ANXA3,IGFBP6,IQGAP1,EPHA4,HMG20B,LOXL2,DDR1,EMP2,DUSP5,HDAC9,IER3,ADD3,SP100,CCDC6,NFKB2,SLC12A2,COL16A1 |
| 3.119e-02 | -3.47 | SU_TESTIS | MSigDB lists | SU_TESTIS | 73 | 17 | 17758 | 2588 |
HMMR,NF2,ITCH,ZMYND10,KIF2C,RAD17,CCNB1,CDK1,IDE,NEK2,ZNF165,SFMBT1,AURKA,BUB1,CCNB2,PHKG2,NXT2 |
| 3.119e-02 | -3.47 | SANA_RESPONSE_TO_IFNG_UP | MSigDB lists | SANA_RESPONSE_TO_IFNG_UP | 73 | 17 | 17758 | 2588 |
MX1,PARP14,LAP3,HLA-E,CD274,SEPT4,LGALS3BP,HLA-A,DTX3L,HLA-B,NLRC5,HLA-C,MLKL,IFIH1,ETV7,APOL2,PARP9 |
| 3.119e-02 | -3.47 | GNF2_MAP2K3 | MSigDB lists | GNF2_MAP2K3 | 73 | 17 | 17758 | 2588 |
TMCC2,ERMAP,MPP1,BLVRB,BNIP3L,FBXO9,EIF2AK1,UBAC1,SPTB,RAD23A,FECH,MARCH8,ANK1,CA2,H1F0,FBXO7,TRAK2 |
| 3.119e-02 | -3.47 | positive regulation of peptidyl-threonine phosphorylation | biological process | GO:0010800 | 26 | 8 | 16441 | 2455 |
PLK1,CALM2,PRKAG2,RIPK2,BMP7,CALM1,CAB39,CALM3 |
| 3.119e-02 | -3.47 | regulation of dendritic spine morphogenesis | biological process | GO:0061001 | 26 | 8 | 16441 | 2455 |
PTEN,BHLHB9,SIPA1L1,EPHA4,EFNA1,ITPKA,CDK5R1,NGEF |
| 3.119e-02 | -3.47 | Schwann cell development | biological process | GO:0014044 | 26 | 8 | 16441 | 2455 |
SOD1,FA2H,AKT1,NDRG1,TFAP2A,MPP5,ILK,DAG1 |
| 3.119e-02 | -3.47 | establishment of spindle orientation | biological process | GO:0051294 | 26 | 8 | 16441 | 2455 |
CENPA,HTT,LLGL2,NDC80,GPSM2,SPDL1,NDE1,SPRY2 |
| 3.121e-02 | -3.47 | ARFGEF2 (ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)) | protein interactions | 10564 | 29 | 9 | 16036 | 2547 |
HLA-B,HLA-E,DNAJB2,PNPLA2,CSGALNACT1,ARFGEF1,VCP,SDF4,PRKAR1A |
| 3.121e-02 | -3.47 | CHMP4A (charged multivesicular body protein 4A) | protein interactions | 29082 | 29 | 9 | 16036 | 2547 |
RCN1,DCK,RANBP1,VPS4B,EFHD2,CHMP4B,F2R,IDH1,EGFR |
| 3.121e-02 | -3.47 | AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase) | protein interactions | 60496 | 29 | 9 | 16036 | 2547 |
PLCG1,DAZAP1,TRAF2,UBE2D2,FBXO6,STIL,ZC3HC1,EHD1,MDFI |
| 3.121e-02 | -3.47 | NRXN1 (neurexin 1) | protein interactions | 9378 | 29 | 9 | 16036 | 2547 |
CASK,SYT7,SIPA1L1,SYT13,APBA1,APBA2,SYTL3,SYTL2,ATP13A2 |
| 3.121e-02 | -3.47 | CCND2 (cyclin D2) | protein interactions | 894 | 29 | 9 | 16036 | 2547 |
CALM2,RB1,CDKN1C,CALM1,BCL6,CALM3,PSMD10,CDKN1B,NPDC1 |
| 3.122e-02 | -3.47 | GGGNNTTTCC_V$NFKB_Q6_01 | MSigDB lists | GGGNNTTTCC_V$NFKB_Q6_01 | 129 | 27 | 17758 | 2588 |
LASP1,CPEB4,TNIP1,HSPG2,TP53,PKN1,PNKD,NFAT5,BMP2K,SH3KBP1,CNTNAP1,TRIM47,STAT6,SLC44A1,NFKBIA,RAP2C,KCNS3,FAM117A,CD70,SP6,GEM,NFKB2,JAK3,SLC12A2,NRGN,PTGES,EHD1 |
| 3.132e-02 | -3.46 | Amino Sugar Metabolism | SMPDB pathways | SMP00045 | 17 | 7 | 978 | 190 |
GFPT1,CMAS,SLC17A5,NANS,UAP1,GNPDA1,GNE |
| 3.132e-02 | -3.46 | G(M2)-Gangliosidosis: Variant B- Tay-sachs disease | SMPDB pathways | SMP00534 | 17 | 7 | 978 | 190 |
GFPT1,CMAS,SLC17A5,NANS,UAP1,GNPDA1,GNE |
| 3.132e-02 | -3.46 | Tay-Sachs Disease | SMPDB pathways | SMP00390 | 17 | 7 | 978 | 190 |
GFPT1,CMAS,SLC17A5,NANS,UAP1,GNPDA1,GNE |
| 3.132e-02 | -3.46 | Sialuria or French Type Sialuria | SMPDB pathways | SMP00216 | 17 | 7 | 978 | 190 |
GFPT1,CMAS,SLC17A5,NANS,UAP1,GNPDA1,GNE |
| 3.132e-02 | -3.46 | Doxorubicin Metabolism Pathway | SMPDB pathways | SMP00650 | 17 | 7 | 978 | 190 |
NQO1,POR,RALBP1,XDH,ABCB1,ABCC1,ABCG2 |
| 3.132e-02 | -3.46 | Sialuria or French Type Sialuria | SMPDB pathways | SMP00217 | 17 | 7 | 978 | 190 |
GFPT1,CMAS,SLC17A5,NANS,UAP1,GNPDA1,GNE |
| 3.132e-02 | -3.46 | Salla Disease/Infantile Sialic Acid Storage Disease | SMPDB pathways | SMP00240 | 17 | 7 | 978 | 190 |
GFPT1,CMAS,SLC17A5,NANS,UAP1,GNPDA1,GNE |
| 3.134e-02 | -3.46 | glial cell projection | cellular component | GO:0097386 | 13 | 5 | 17570 | 2579 |
AKR1B1,EZR,PINK1,ADGRG1,GRM5 |
| 3.137e-02 | -3.46 | CTNS | smart domains | SM00679 | 5 | 3 | 9131 | 1455 |
PQLC2,CTNS,PQLC3 |
| 3.137e-02 | -3.46 | BRO1 | smart domains | SM01041 | 5 | 3 | 9131 | 1455 |
RHPN2,BROX,RHPN1 |
| 3.140e-02 | -3.46 | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | 84 | 19 | 17758 | 2588 |
DOCK4,ARAP2,ASXL1,HOXB2,DUSP5,ACAP2,TGFBR3,SP100,IGF1R,PTEN,DLG1,ATP8B1,SFMBT1,WWP1,MPHOSPH9,MSH6,RPS6KA3,DOCK9,ABCC1 |
| 3.145e-02 | -3.46 | TCCATTKW_UNKNOWN | MSigDB lists | TCCATTKW_UNKNOWN | 223 | 43 | 17758 | 2588 |
SPRED1,PPP1R12A,HSPG2,CHCHD7,DDIT4L,ETV5,FTH1,EGR3,BCL2L1,SEPT4,GNB2,BEX2,SCML1,CCDC92,BMP2,ATP6V0B,CDKL5,TSPAN6,DPYSL2,CALD1,CABP1,IL6ST,LMO4,DUSP10,TSPAN13,CACNA1D,DLG3,CCDC88A,NR3C1,TACC1,NR4A1,ITCH,VAMP3,SRSF5,TMTC2,PTGFRN,MAP2,NR4A3,AURKA,CTNND1,ZNF502,JARID2,NR2C2 |
| 3.149e-02 | -3.46 | XU_GH1_AUTOCRINE_TARGETS_UP | MSigDB lists | XU_GH1_AUTOCRINE_TARGETS_UP | 229 | 44 | 17758 | 2588 |
UGT8,PPM1J,BLVRB,GMPR,HERC5,PBX3,AES,FAM198B,OAT,SEPP1,MERTK,PGAP1,SH3KBP1,NRP2,RNF220,LRRN2,BMP7,PRC1,ECI2,CPE,RIMS2,SMAGP,P2RX4,SGCE,SPEF2,SOD1,GGH,CDCA2,ROR1,ALCAM,C4orf27,SFXN5,STEAP1,MYL12A,STK17A,CNTNAP1,TSC1,SLC25A4,AXL,STARD13,CDAN1,NR3C2,RPS6KA3,CYBRD1 |
| 3.152e-02 | -3.46 | spindle pole centrosome | cellular component | GO:0031616 | 9 | 4 | 17570 | 2579 |
AURKA,AURKB,NDE1,DLGAP5 |
| 3.152e-02 | -3.46 | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | MSigDB lists | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | 57 | 14 | 17758 | 2588 |
CPD,GNS,SORT1,AP1M2,TBC1D8B,SH3D19,OCRL,DNM2,ARRB1,TGOLN2,CTSZ,FTH1,SNX9,M6PR |
| 3.152e-02 | -3.46 | CCACACA,MIR-147 | MSigDB lists | CCACACA,MIR-147 | 57 | 14 | 17758 | 2588 |
ATP1A1,ANK1,GPRC5B,CAPN6,NR3C1,RGS3,CYP2S1,CTDSPL,SLC44A1,TRIOBP,MAL2,TIPARP,NFAT5,KLF7 |
| 3.152e-02 | -3.46 | MODULE_199 | MSigDB lists | MODULE_199 | 57 | 14 | 17758 | 2588 |
FGFR2,PTK7,AXL,EPHA4,MYLK,RYK,DAPK1,ERBB2,IL13RA1,PDGFRL,ROR1,MERTK,LEPR,CDK5R1 |
| 3.152e-02 | -3.46 | chr18p11 | MSigDB lists | chr18p11 | 57 | 14 | 17758 | 2588 |
DLGAP1,TGIF1,NAPG,TWSG1,RALBP1,PPP4R1,GNAL,NDC80,RAB31,ANKRD12,YES1,MYOM1,MYL12A,MYL12B |
| 3.152e-02 | -3.46 | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | MSigDB lists | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | 57 | 14 | 17758 | 2588 |
CD109,COL9A3,TIMP3,COL6A2,CYR61,ITGA7,ZFP36,ATP8A1,FOSB,PPFIBP2,SORL1,NDRG2,ARVCF,MERTK |
| 3.153e-02 | -3.46 | protein C-terminus binding | molecular function | GO:0008022 | 178 | 36 | 16491 | 2452 |
BCAM,HSPG2,PEX6,PRKAA1,ERBB2,BAIAP3,FBLN1,SDC1,HPCAL4,SLC9A3R2,PICK1,TOP2A,CTGF,CTNNB1,DLG1,MSH2,TAX1BP3,TRIM3,ERCC2,DLG3,SIRT1,FBLN5,KCNIP3,CDC20,VPS4B,ATP1B1,PLEKHB1,OPTN,BCL10,PIAS3,NEIL1,MID1IP1,PEX5,PRDX3,SPTBN5,CTBP1 |
| 3.159e-02 | -3.45 | Hippo signaling pathway | KEGG pathways | ko04390 | 154 | 33 | 6908 | 1076 |
NF2,FRMD6,TGFBR1,MPP5,APC2,TEAD3,FZD6,BMP2,CCND1,TP73,CTGF,CDH1,CTNNB1,LLGL2,BMP7,DLG1,PRKCI,PPP1CA,WNT3A,DLG3,DVL2,WNT10B,FZD4,SCRIB,TCF7,SAV1,FZD7,AREG,WWTR1,NKD1,PPP1CB,FZD5,PPP2R2D |
| 3.159e-02 | -3.45 | Hippo signaling pathway | KEGG pathways | hsa04390 | 154 | 33 | 6908 | 1076 |
NF2,FRMD6,TGFBR1,MPP5,APC2,TEAD3,FZD6,BMP2,CCND1,TP73,CTGF,CDH1,CTNNB1,LLGL2,BMP7,DLG1,PRKCI,PPP1CA,WNT3A,DLG3,DVL2,WNT10B,FZD4,SCRIB,TCF7,SAV1,FZD7,AREG,WWTR1,NKD1,PPP1CB,FZD5,PPP2R2D |
| 3.160e-02 | -3.45 | skin-buttock-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-buttock-other-atypical_Spitzoid_tumour | 22 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.160e-02 | -3.45 | skin-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-other-atypical_Spitzoid_tumour | 22 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.160e-02 | -3.45 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 22 | 7 | 17775 | 2585 |
RB1,RHOA,CBL,CTNNB1,IDH1,PTEN,TP53 |
| 3.160e-02 | -3.45 | bone-skull-chordoma | COSMIC cancer mutations | bone-skull-chordoma | 22 | 7 | 17775 | 2585 |
CTNNB1,IDH1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 3.160e-02 | -3.45 | skin-face-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-face-benign_melanocytic_nevus-Spitz | 22 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.160e-02 | -3.45 | skin-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-basal_cell_carcinoma | 22 | 7 | 17775 | 2585 |
NOTCH2,CTNNB1,AKT1,EGFR,SMO,PIK3CA,TP53 |
| 3.160e-02 | -3.45 | skin-upper_arm-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-upper_arm-other-atypical_Spitzoid_tumour | 22 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.160e-02 | -3.45 | skin-arm-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-arm-benign_melanocytic_nevus-Spitz | 22 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.160e-02 | -3.45 | skin-lower_leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-lower_leg-benign_melanocytic_nevus-Spitz | 22 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.160e-02 | -3.45 | skin-knee-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-knee-benign_melanocytic_nevus-Spitz | 22 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.164e-02 | -3.45 | positive regulation of mitotic cell cycle | biological process | GO:0045931 | 115 | 25 | 16441 | 2455 |
PLK1,HES1,NKX3-1,DLGAP5,WNT10B,CUL4B,VPS4B,RGCC,KIF20B,NUSAP1,CCNB1,PDGFB,CCND1,RB1,CYP1A1,INSR,IGF1R,PTEN,CDCA5,AURKA,XRCC3,UBE2C,GEN1,ESPL1,FOXA1 |
| 3.171e-02 | -3.45 | Aldosterone-regulated sodium reabsorption | KEGG pathways | hsa04960 | 39 | 11 | 6908 | 1076 |
ATP1A1,INSR,SCNN1A,PIK3R1,PIK3CA,SGK1,ATP1B3,PIK3CD,ATP1B1,NR3C2,SLC9A3R2 |
| 3.171e-02 | -3.45 | Aldosterone-regulated sodium reabsorption | KEGG pathways | ko04960 | 39 | 11 | 6908 | 1076 |
ATP1A1,INSR,SCNN1A,PIK3R1,PIK3CA,SGK1,ATP1B3,PIK3CD,ATP1B1,NR3C2,SLC9A3R2 |
| 3.173e-02 | -3.45 | Signal Transduction of S1P Receptor | WikiPathways | WP26 | 24 | 8 | 4455 | 729 |
AKT1,ASAH1,PIK3C2B,RACGAP1,MAPK4,MAPK7,PLCB2,MAPK12 |
| 3.173e-02 | -3.45 | IL-9 Signaling Pathway | WikiPathways | WP22 | 24 | 8 | 4455 | 729 |
IRS2,JAK1,AKT1,PIK3R1,STAT1,JAK3,VCP,SOCS3 |
| 3.180e-02 | -3.45 | nucleoside-triphosphatase activity | molecular function | GO:0017111 | 763 | 132 | 16491 | 2452 |
ATP8A1,KLC2,TAP1,SMARCAL1,DHX8,KIF2C,SEPT4,KIF26A,PICK1,ABCD4,RAB15,HELZ2,DNAH6,ARL1,PSMC2,ATP13A3,ABCA2,DNM2,TUBG1,RAB20,KIF22,MYH14,DDX59,TUBA4A,ATL1,SMARCA2,KIFC2,ARHGDIB,KIF13A,ARFRP1,PIF1,RHEB,VCP,RAB2B,GINS4,ARF4,DNM1L,ATP7B,PPP2R4,ARF6,RAP1GAP,PSMC1,RRAGD,DDX58,RECQL,PEX6,RAB23,ABCG2,ATP6V1E2,KIF23,RAB6A,MYO5C,RAC2,ATP5H,KIF13B,PCYOX1,MSH2,SRP54,DNAI1,ABCC1,KIF20A,KIF20B,ATP8B3,GNA11,RHOB,DHX32,GNAS,RAB31,ATP1B3,KIF12,IFIH1,KIF3C,DYNLRB1,TUBB4B,RALBP1,ATP2C2,ABCG4,MRAS,GNB2,APPBP2,ATP6V0B,RALB,KIF14,ARL4D,RAB27B,MX1,MYO5B,FIGNL1,VPS4B,KIF1C,ATP1B1,RAD17,RAB38,ATP10D,ATP13A2,TAPBP,IDE,ATP1A1,XRCC3,RAB29,ABCA1,SHPRH,ATP9A,GNAL,ERCC6L,ARL4C,DNAH3,IFT27,RND1,DIRAS3,KIF5B,TOP2A,GNB5,GTF2F2,KLC3,ATP8B1,ABCD1,ERCC2,MSH6,ATP2B1,MYO5A,RAB3B,RHOA,LONRF3,KIF11,DDX23,RND3,ABCB1,CENPE,ATP6V1C1,GEM,ABCG1 |
| 3.181e-02 | -3.45 | human chr2q22-q23 | chromosome location | human chr2q22-q23 | 3 | 2 | 26250 | 2805 |
NR4A2,CACNB4 |
| 3.181e-02 | -3.45 | human chr2q23.2 | chromosome location | human chr2q23.2 | 3 | 2 | 26250 | 2805 |
LYPD6,MMADHC |
| 3.181e-02 | -3.45 | human chr3q28-q29 | chromosome location | human chr3q28-q29 | 3 | 2 | 26250 | 2805 |
HES1,MFI2 |
| 3.183e-02 | -3.45 | salivary_gland-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-adenoid_cystic_carcinoma | 507 | 89 | 17775 | 2585 |
SLC25A24,CAPN12,HSPG2,TRIP10,TP53,ERBB2,SLC9A7,CALM2,TYMP,SIPA1L2,MUC16,MUC4,CTNNB1,SP100,LHX6,PIK3CA,ANKRD12,BRI3,TNPO2,ARNT2,ACOX2,LRP11,MYBL1,ERAP2,ZNF462,SMARCA2,TNIP1,LAP3,SERTAD4,ERBB2IP,TANC1,IDH1,NFIX,DUOX1,FAM177A1,PTPRJ,OVOL1,KLF5,IRF7,TANC2,AIFM3,TNRC6C,ZNF395,CHCHD7,NOTUM,TSPAN17,FOXP2,RB1,ANK1,ITGB8,IRAK1,PTEN,CD22,FRAS1,FCHO1,OPN3,PRKG1,TFAP2A,PRKCI,FNIP1,USP38,IGFBP2,USP1,KNTC1,MPHOSPH9,ARHGEF28,ARAP2,PTPRH,ELOVL3,SPATA13,BTN3A2,KIF20B,COL7A1,RNPEP,NFIB,EGFR,FAT4,SEMA4D,NAB2,FGD6,DYSF,NXPH4,PKD2,CENPE,ZMIZ1,OSR1,TOB1,L1CAM,ADAMTS16 |
| 3.185e-02 | -3.45 | toll-like receptor 4 signaling pathway | biological process | GO:0034142 | 104 | 23 | 16441 | 2455 |
RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PIK3AP1,PELI2,NFKBIA,UBE2D2,NOD2,MAPK11,IRF7,MAP3K7,NFKB2,MAPK7,PPP2R5D,RPS6KA3 |
| 3.188e-02 | -3.45 | human chr1p36.3 | chromosome location | human chr1p36.3 | 12 | 4 | 26250 | 2805 |
TP73,TNFRSF18,GABRD,ARHGEF16 |
| 3.190e-02 | -3.45 | NEDD9 (neural precursor cell expressed, developmentally down-regulated 9) | protein interactions | 4739 | 43 | 12 | 16036 | 2547 |
BCAR3,ZYX,FYN,CDH1,ITCH,SH2D3C,NFKBIA,NAB2,PIK3CA,AURKA,NOTCH3,BCAR1 |
| 3.193e-02 | -3.44 | YANG_BREAST_CANCER_ESR1_BULK_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_BULK_DN | 22 | 7 | 17758 | 2588 |
DSE,APBA2,ASPM,KCNK5,PLAUR,SIRPA,RIN3 |
| 3.193e-02 | -3.44 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE | 22 | 7 | 17758 | 2588 |
CHSY3,B3GALT6,DSE,XYLT2,XYLT1,CHPF,CSGALNACT1 |
| 3.193e-02 | -3.44 | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | 22 | 7 | 17758 | 2588 |
PIM1,IDH1,ST3GAL1,PLCB2,NDRG1,LBR,IER3 |
| 3.193e-02 | -3.44 | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | MSigDB lists | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | 22 | 7 | 17758 | 2588 |
SGK1,HLF,TIMP3,GEM,WDR44,RASGRP1,MITF |
| 3.193e-02 | -3.44 | MODULE_372 | MSigDB lists | MODULE_372 | 22 | 7 | 17758 | 2588 |
KLHL2,CCNE2,FOXP2,SOX8,TWSG1,KIF11,MSH2 |
| 3.193e-02 | -3.44 | HINATA_NFKB_TARGETS_KERATINOCYTE_DN | MSigDB lists | HINATA_NFKB_TARGETS_KERATINOCYTE_DN | 22 | 7 | 17758 | 2588 |
KLK6,KLK7,ESYT1,DUSP4,SULT2B1,RIMS2,DAPK1 |
| 3.193e-02 | -3.44 | PID_PDGFRA_PATHWAY | MSigDB lists | PID_PDGFRA_PATHWAY | 22 | 7 | 17758 | 2588 |
PLCG1,ITGAV,JAK1,ELK1,FOS,PIK3R1,PIK3CA |
| 3.193e-02 | -3.44 | NEWMAN_ERCC6_TARGETS_UP | MSigDB lists | NEWMAN_ERCC6_TARGETS_UP | 22 | 7 | 17758 | 2588 |
HERC5,MYLIP,STEAP1,SLC25A40,ABCB1,LITAF,PCSK5 |
| 3.193e-02 | -3.44 | BIOCARTA_INSULIN_PATHWAY | MSigDB lists | BIOCARTA_INSULIN_PATHWAY | 22 | 7 | 17758 | 2588 |
SLC2A4,INSR,ELK1,FOS,RASA1,PIK3R1,PIK3CA |
| 3.199e-02 | -3.44 | P-loop_NTPase | interpro domains | IPR027417 | 853 | 144 | 18293 | 2672 |
NMRK1,AK7,TAP1,SMARCAL1,DHX8,MPP5,KIF2C,SEPT4,CACNB4,KIF26A,CARD10,CHST2,ABCD4,RAB15,HELZ2,DNAH6,IQCE,ARL1,PAPSS1,PSMC2,DLG1,ABCA2,DNM2,KIF22,RAB20,MYH14,DDX59,NLRP4,ATL1,SMARCA2,SPEF2,NWD1,KIFC2,KIF13A,ARFRP1,PIF1,RAB2B,RHEB,VCP,ARF4,HS6ST1,DNM1L,NOD2,TANC2,ARF6,PSMC1,HS6ST3,RRAGD,DDX58,RECQL,PEX6,ABCG2,RAB23,KIF23,SAMD9,RAB6A,MYO5C,RAC2,KIF13B,MSH2,DAPK1,CTPS1,TPST1,SRP54,ABCC1,KIF20A,KIF20B,NPHP3,NUBP1,GNA11,RHOB,DHX32,GNAS,TJP3,DCK,RAB31,MPP2,NLRC5,RHOBTB2,KIF12,IFIH1,EHD1,KIF3C,PAPSS2,IQGAP1,ABCG4,MRAS,TRANK1,RALB,KIF14,RAB27B,DLG3,ARL4D,SULT2B1,MX1,MYO5B,PFKFB2,FIGNL1,SEPT6,VPS4B,TEP1,KIF1C,RAB38,RAD17,TANC1,ARHGAP35,XRCC3,RAB29,HS3ST3B1,ABCA1,NDST3,TOR4A,SHPRH,GNAL,ERCC6L,ARL4C,IFT27,DNAH3,RND1,KIF5B,DIRAS3,ABCD1,AK3,ERCC2,MYO5A,MSH6,SMC4,RAB3B,RHOA,CASK,ASPM,MPP1,AK4,KIF11,DDX23,RND3,RAP2C,ABCB1,RABL6,CENPE,LRRK1,GEM,CMPK2,ABCG1 |
| 3.200e-02 | -3.44 | activation of phospholipase C activity | biological process | GO:0007202 | 61 | 15 | 16441 | 2455 |
CALM2,PLCG1,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2,EGFR,EDNRA,PRKAR1A,TXK |
| 3.200e-02 | -3.44 | glycosaminoglycan catabolic process | biological process | GO:0006027 | 61 | 15 | 16441 | 2455 |
HMMR,GNS,FUCA1,AGRN,HPSE,HSPG2,GUSB,GPC3,GALNS,HEXB,SDC4,GLB1,ARSB,SDC1,CHP1 |
| 3.201e-02 | -3.44 | BIOPOLYMER_METABOLIC_PROCESS | MSigDB lists | BIOPOLYMER_METABOLIC_PROCESS | 1660 | 268 | 17758 | 2588 |
GAA,ACVR1,TRIM24,SSH1,TSC22D3,RET,FBXO2,SMARCAL1,CCNO,GATA3,DHX8,PICK1,DAPK2,TP73,TYMP,ZFP36,IL31RA,FOSB,FUT1,POLL,IRF2,PPP1CA,APOBEC3G,METAP2,NEK4,SMARCA2,RNF11,MGAM,TFAP2C,PIF1,GALNT7,LOXL2,ICMT,PRIM1,HLF,LIMK1,MYLK,PPP2R4,MAP3K11,RECQL,CDK17,PRKAA1,NOTCH2,MERTK,TSPAN7,ELF3,RABGGTA,CALR,TFAP4,FBXO7,TPST1,DAPK1,PRKG1,MSH2,MAP3K9,STT3B,MYLIP,NAGPA,PIGC,REC8,DDB2,QSOX1,UFD1L,PTPRH,SRSF5,ILK,ELK1,STK17A,MMP15,FNTA,AURKA,ALG2,IRF1,DMPK,TCF25,S100A11,THRA,PTTG1,TESK2,MAPK4,EPM2A,CCND1,SP100,RNASEH2A,PHKA2,CDKN2D,MED30,COG2,PTPN9,DRAP1,TEP1,VPS4B,HTATIP2,RAD17,XRCC6BP1,CBL,SP4,NFIX,KIAA1804,STAT1,KLF5,MAPK12,PRKAR1A,MAN1A2,PBX3,PKN1,NFAT5,WWP2,CTNNBIP1,FUT2,PTEN,MGAT4A,FUT8,SGK3,BAX,WWP1,ERCC2,ERBB3,RAG1,CITED2,GFI1,MSH6,TGIF1,TCFL5,PARP4,FURIN,DBR1,UBE2A,YES1,FOS,TXK,PITX2,NR1D2,ACVRL1,PLOD2,NR4A3,CSTF2,HMGA1,CD81,SRSF9,TNK1,EPAS1,TAF6L,HDAC6,ARHGEF10L,HSF2,P4HB,CDKL5,ELF5,ABCA2,DUSP10,ASH2L,PTPRE,PTPN18,KCNIP3,MARK1,SOD1,NFE2L1,STK17B,VCP,KLF12,ZNF367,DOLPP1,KPNA2,KLF11,POMT1,MAFF,PCSK5,NR2C2,PRKAA2,DUSP5,BMP2,B3GALNT1,RB1,IGF1R,GATA2,PAK2,PRKCI,MDFIC,PIM1,ETV7,GAD1,CCDC88A,MDFI,MGAT4B,STRADB,TCF7,EIF2AK1,NMT2,EGFR,MAPKAPK2,TSC1,INSR,JAK3,CTBP1,RAD21,KLF7,NF2,HDAC11,TP53,SOD2,ERBB2,RAD23A,PPME1,LMO4,PLK4,BCL6,RPN2,TWIST1,NFKB2,LOXL1,F2R,SEPHS1,MAP3K3,SIRT1,TAF5,AKT1,TCEB2,PTPRU,CDC20,DUSP4,SNAPC2,MAP3K6,HSF4,PTPRJ,STK38,IRF7,XRCC3,GLIS3,DYRK3,PINK1,ARHGEF11,GTF3A,TGFBR1,INTS8,POMGNT1,SBF1,TRIB2,CRABP2,PPP2R3A,TOP2A,CDK16,TFAP2A,GTF2F2,BRD7,SGK1,KLF9,HEXIM2,SLC35A1,RBMS2,GCNT1,NFE2L3,NR3C1,AMFR,PPARA,LITAF,RUNX3,BCL10,DDX23,PRDX4,NMI,UBE2D2,E2F1,CSGALNACT1,PLOD3,UBE2C,HIPK3,AHR |
| 3.208e-02 | -3.44 | Znf_NHR/GATA | interpro domains | IPR013088 | 57 | 14 | 18293 | 2672 |
THRB,NR3C1,GATA2,NR1D2,NR4A1,THRA,PPARA,NR4A3,GATA3,NR4A2,RARG,NR2C1,NR3C2,NR2C2 |
| 3.214e-02 | -3.44 | - | gene3d domains | 3.40.50.1000 | 63 | 16 | 9988 | 1574 |
CMAS,ATP9A,ATP8A1,CTDSPL,PHOSPHO1,ATP8B3,LPIN3,ATP10D,ATP13A2,NT5C2,ACAD10,ATP7B,ATP13A3,ATP8B1,CTDSP2,CTDSP1 |
| 3.216e-02 | -3.44 | CTBP1 (C-terminal binding protein 1) | protein interactions | 1487 | 151 | 33 | 16036 | 2547 |
PRKAA1,TP53,ZNF219,HDAC9,MECOM,FOXP2,TFAP4,RB1,E2F7,CTNNB1,KLF3,BCL6,TUBG1,CRY2,ARNT2,ZBTB18,EEF1D,CTH,PLK1,TGIF1,ELK3,AKT1,CDYL,C15orf39,EGFR,KLF12,HTT,RBL1,PIAS2,HDAC1,SSNA1,CTBP1,CBX4 |
| 3.226e-02 | -3.43 | CREB phosphorylation through the activation of CaMKII | REACTOME pathways | R-HSA-442729 | 17 | 6 | 8202 | 1235 |
CALM3,CALM2,GRIN2D,CALM1,CAMK2G,GRIN1 |
| 3.227e-02 | -3.43 | WW domain binding | molecular function | GO:0050699 | 31 | 9 | 16491 | 2452 |
SCNN1A,RAPGEF2,TCEAL4,LITAF,DNM2,KIF20B,CDC25C,TCEAL8,WBP5 |
| 3.227e-02 | -3.43 | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | molecular function | GO:0015662 | 31 | 9 | 16491 | 2452 |
ATP1A1,ATP7B,ATP2C2,PCYOX1,ATP6V1E2,ATP1B1,ATP1B3,ATP6V1C1,ATP2B1 |
| 3.228e-02 | -3.43 | buttock | COSMIC cancer mutations | buttock | 68 | 16 | 17775 | 2585 |
CEP89,PTPRH,TP53,TNS1,NOTCH2,GNA11,LMNA,HLA-A,TNS4,EPHA10,KIF5B,RB1,PTPRJ,PTK7,PTPRE,MYO5A |
| 3.228e-02 | -3.43 | Ras-like_Gua-exchang_fac_N | interpro domains | IPR000651 | 22 | 7 | 18293 | 2672 |
RASGRF1,RASGRP3,RASGEF1A,RAPGEF2,KNDC1,RASGRP1,RASGRP2 |
| 3.228e-02 | -3.43 | Guanylate_kin-like_dom | interpro domains | IPR008144 | 22 | 7 | 18293 | 2672 |
MPP5,CASK,TJP3,DLG3,MPP1,DLG1,MPP2 |
| 3.228e-02 | -3.43 | regulation of peptidase activity | biological process | GO:0052547 | 397 | 73 | 16441 | 2455 |
CASP3,RPS6KA1,CAST,PSME2,PTTG1,RET,XIAP,PSME1,BCAP31,APLP2,CTGF,CDKN1B,EGLN3,CDKN2D,F2R,SIRT1,TIMP2,AKT1,ACVR1C,CASP9,SLC11A2,POR,VCP,NGFRAP1,SERPINB6,SERPINI1,MAPK12,NKX3-1,PCOLCE,PINK1,SERPINE2,TRAF2,DAP,SERPINB9,FBLN1,CD109,TFAP4,CARD8,TIMP1,CYR61,CTSC,GPC3,CST3,PAK2,BAX,DAPK1,SORL1,FNIP1,WNT3A,RAG1,RHOA,PLAUR,FURIN,COL7A1,BCL2L13,CYFIP2,FAS,BCL10,TIMP3,CASP7,SERPINA1,KIAA0141,HTT,PRDX3,SPINT2,ARRB1,SERPINB5,GPER1,MAP3K5,SERPINB1,IFI6,RPS6KA3,XDH |
| 3.230e-02 | -3.43 | chest | COSMIC cancer mutations | chest | 147 | 30 | 17775 | 2585 |
ADAMTS2,AKT1,CEP89,PTPRH,RET,PIK3R1,TP53,ERBB2,TNS1,SLC17A5,IDH1,FLT3,GNA11,EGFR,LMNA,HLA-A,KIF5B,TNS4,EPHA10,PLCH1,PTPRJ,CTNNB1,PTEN,FGFR2,PTK7,MITF,PIK3CA,ARRB1,PTPRE,MYO5A |
| 3.235e-02 | -3.43 | Sulfatase | pfam domains | PF00884 | 17 | 6 | 16629 | 2504 |
GNS,ARSB,ARSK,ARSG,GALNS,SULF2 |
| 3.236e-02 | -3.43 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular function | GO:0001077 | 225 | 44 | 16491 | 2452 |
RUNX2,EPAS1,SOX9,TP53,GATA3,NFAT5,SIX4,TFAP2E,ELF3,TP73,TFAP4,GRHL1,GATA2,MITF,FOSB,EBF4,TFAP2A,ARNT2,NFKB2,MYBL1,ETV4,ELK3,PLSCR1,NR3C1,FOXJ2,NR4A1,MYBL2,PPARA,TFAP2C,ELK1,FOS,NFIB,EBF2,TXK,PITX2,NCOA3,ONECUT1,NR4A3,KLF5,NR4A2,AKNA,HOXC13,FOXA1,IRF1 |
| 3.238e-02 | -3.43 | appendage morphogenesis | biological process | GO:0035107 | 149 | 31 | 16441 | 2455 |
CYP26B1,RUNX2,GRHL2,FMN1,SALL4,LRP4,SOX9,RAB23,OSR2,CRABP2,FZD6,MECOM,GNAS,CTNNB1,FGFR2,IMPAD1,BMP7,MEGF8,GPC3,HOXA9,FRAS1,TRAF3IP1,BAX,TFAP2A,HDAC1,TWIST1,ECE1,OSR1,SHOX2,RARG,PCSK5 |
| 3.238e-02 | -3.43 | limb morphogenesis | biological process | GO:0035108 | 149 | 31 | 16441 | 2455 |
CYP26B1,RUNX2,GRHL2,FMN1,SALL4,LRP4,SOX9,RAB23,OSR2,CRABP2,FZD6,MECOM,GNAS,CTNNB1,FGFR2,IMPAD1,BMP7,MEGF8,GPC3,HOXA9,FRAS1,TRAF3IP1,BAX,TFAP2A,HDAC1,TWIST1,ECE1,OSR1,SHOX2,RARG,PCSK5 |
| 3.239e-02 | -3.43 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma | 90 | 20 | 17775 | 2585 |
SGCE,LCA5,AKT1,NR3C1,TP53,ERBB2,IDH1,TXNDC11,EGFR,PRX,SS18,RB1,DNAJC10,CTNNB1,CDH1,PTEN,CDK19,PIK3CA,SORL1,TRAF5 |
| 3.242e-02 | -3.43 | KEGG_GNRH_SIGNALING_PATHWAY | MSigDB lists | KEGG_GNRH_SIGNALING_PATHWAY | 101 | 22 | 17758 | 2588 |
MAP3K3,PLA2G4A,CALM1,CALM3,PLD2,ITPR2,ITPR3,ELK1,PRKACA,GNA11,EGFR,GNAS,CALM2,ITPR1,MAPK13,MAPK11,CACNA1D,PLD1,MAPK7,PLCB2,CAMK2G,MAPK12 |
| 3.248e-02 | -3.43 | V$ATF6_01 | MSigDB lists | V$ATF6_01 | 118 | 25 | 17758 | 2588 |
SEC23A,SPATA18,NR4A1,DNAJB2,KDELR3,EGR3,NANS,DUSP4,ZFAND5,VCP,ARF4,IRX3,PITX2,COQ10A,PPP1R10,LMO4,MADD,TRPC1,TWIST1,TSPAN13,KLF9,KDELR1,GOLGB1,PHC1,SEMA3B |
| 3.250e-02 | -3.43 | glycerophospholipid biosynthetic process | biological process | GO:0046474 | 195 | 39 | 16441 | 2455 |
PLA2G4A,MTM1,INPPL1,CDS2,INPP5D,PNPLA2,ETNK1,PHOSPHO1,PLD2,PLA2G16,CDIPT,LPIN3,PIGL,PGAP1,CDS1,INPP5E,PTEN,OCRL,SLC44A1,PLCG2,PIK3CA,SLC44A2,PIK3CD,PIKFYVE,FAR1,PIGC,PLSCR1,LPGAT1,PLAUR,PIK3R1,SLC44A3,PI4K2B,AGPAT2,INPP4B,DGAT2,SLC27A1,PIK3C2B,PLD1,CHPT1 |
| 3.250e-02 | -3.43 | ATF2_S_UP.V1_DN | MSigDB lists | ATF2_S_UP.V1_DN | 176 | 35 | 17758 | 2588 |
SORBS1,PLSCR4,ENO2,GALNT12,KCTD12,SLC1A3,PLA2G16,VASH1,KBTBD11,LTBP3,DAPK1,RGS5,IGFBP2,IL1RAP,CYP1B1,SLC39A8,CRIP2,AK4,COL7A1,ROR1,FOS,NFIB,IL1R1,PTGS2,GABRD,PDLIM3,PTER,SPINT2,ITPR1,CSGALNACT1,CLMN,OSMR,CBX7,COL16A1,NXT2 |
| 3.250e-02 | -3.43 | JNK_DN.V1_DN | MSigDB lists | JNK_DN.V1_DN | 176 | 35 | 17758 | 2588 |
MYL9,INPPL1,DYRK3,CRYM,NDRG2,PDGFB,ETS1,NRP2,RND1,TYMP,VASP,CYP1A1,CABP1,FABP6,KIF22,KNTC1,STK35,GCNT1,SEMA3B,PLK1,QSOX1,PTPN18,BCL9,DUSP4,STEAP1,MFSD7,MAP1B,COL13A1,ACVRL1,EFNA5,RCAN2,ARHGAP4,RGS14,NRGN,UBE2C |
| 3.250e-02 | -3.43 | LEE_LIVER_CANCER_SURVIVAL_UP | MSigDB lists | LEE_LIVER_CANCER_SURVIVAL_UP | 176 | 35 | 17758 | 2588 |
UNKL,PINK1,FAM169A,CPT2,CYP2J2,C6orf106,NDRG2,ITPR2,SEPT4,PHLPP1,SGPL1,CES2,CYP4F11,BDH1,ENPP5,RUNDC3B,AOX1,ACOX2,MYRIP,TTPA,FAM134C,EPHX1,PCCB,ADCK3,AMFR,PARD3B,OGDHL,F12,AMDHD1,SEC14L2,INSR,CGREF1,CABIN1,ANXA9,DENND5B |
| 3.252e-02 | -3.43 | negative regulation of protein dephosphorylation | biological process | GO:0035308 | 77 | 18 | 16441 | 2455 |
CAMSAP3,SPRED1,FARP1,BAG4,LMTK3,PPP4R4,PKMYT1,TIPRL,SH2D4A,SYTL2,SH3RF2,SWAP70,SEMA4D,PPP2R4,CRY2,DLG3,CHP1,ARFGEF3 |
| 3.253e-02 | -3.43 | G1/S Transition | REACTOME pathways | R-HSA-69206 | 109 | 24 | 8202 | 1235 |
CCNE2,PSMB4,PSME2,PSMD7,CUL1,PSMD10,PSME1,PKMYT1,CCNB1,CDK1,PSMA4,PRIM1,RB1,WEE1,PCNA,PSMD1,CCNA2,PSMD3,PSMC2,E2F1,CDKN1B,CKS1B,PSMC1,PSMA5 |
| 3.256e-02 | -3.42 | KATSANOU_ELAVL1_TARGETS_DN | MSigDB lists | KATSANOU_ELAVL1_TARGETS_DN | 141 | 29 | 17758 | 2588 |
SHMT1,COL6A2,DEPDC1,HMGN5,EPS8,TEP1,MYBL2,TTC7A,PKMYT1,MNS1,STEAP1,DDX23,TFAP4,TGFBR3,ETS2,NPNT,STK38,CDCA7L,COL6A1,TNPO2,CLIP4,DUSP10,OSMR,CDH3,SGK1,ALDH7A1,UBE2C,ETV4,TIAM1 |
| 3.263e-02 | -3.42 | Guanylate_kin | pfam domains | PF00625 | 26 | 8 | 16629 | 2504 |
CASK,TJP3,MPP1,DLG1,MPP2,MPP5,DLG3,CACNB4 |
| 3.266e-02 | -3.42 | TGTTTGY_V$HNF3_Q6 | MSigDB lists | TGTTTGY_V$HNF3_Q6 | 696 | 119 | 17758 | 2588 |
LTBP1,ACVR1,CEP70,REPS2,GRIK2,THRA,TSC22D3,FHDC1,IL18,OSR2,OAT,PCBP1,DENND2D,ECI1,EPS8L2,CDK14,RAD23A,SIPA1L2,SESN3,ST5,CTGF,GRHL1,SHC3,WDR44,NPNT,RGS3,ELF5,KLF3,FOSB,MITF,SLC44A1,BCL6,DUSP10,CRY2,NTN4,PDE4D,ZNF462,SMARCA2,KCNIP3,ASXL1,SYNE2,CBX6,KIF13A,ITPR3,H2AFV,SP4,EBF2,OSBPL2,TAPBP,RBM47,KLF12,PAFAH1B3,NKD1,MYLK,NRG1,KLF5,EFNA5,REEP4,HOXC13,CTDSP1,BMF,FRMD4A,NFKBIE,ZNF395,ADO,MCTP2,FAM134A,TGFBR1,CNTNAP2,CRABP2,TSPAN7,PPP2R3A,GBX2,TFAP4,FOXP2,ITGA3,CYR61,CALD1,BDH1,ZIC5,SGK3,ADAM15,SGK1,H2AFY,KANK2,TAGLN2,ERBB3,NCAM1,NTN1,CITED2,MAST4,DUSP1,NFE2L3,TGIF1,PHF20L1,LONRF3,MGAT4B,PDIK1L,MUM1L1,PRX,GPLD1,PITX2,LEMD2,BTG1,SERPINA1,H1F0,E2F1,NR4A3,EGFL7,EFNA1,SEMA3A,SHROOM2,TOB1,RNF146,KLF7,JARID2,RAD21,DOCK9,GOLGB1 |
| 3.270e-02 | -3.42 | TGCACTG,MIR-148A,MIR-152,MIR-148B | MSigDB lists | TGCACTG,MIR-148A,MIR-152,MIR-148B | 290 | 54 | 17758 | 2588 |
RMND5A,LTBP1,ACVR1,RUNX2,PPP1R12A,CPEB4,RBM24,RALBP1,PRKAA1,KLC2,ETV5,ARFGEF1,C5orf30,PDIA3,SEPT4,SNN,DNER,LBR,SIX4,E2F7,MGAT4A,FAM13B,MITF,ELF5,FOSB,MAP3K9,MDFIC,NPTN,ERBB3,MARCH2,BTBD3,PPP6R1,TRAK2,CPD,MLEC,WNT10B,MMD,RNF165,WHSC1,STRADB,MUM1L1,STX3,CDK5R1,USP6,PRKAG2,GPRC5B,CDK19,CSF1,BMP1,PPP1CB,STARD13,ABCA1,RGMA,SNPH |
| 3.273e-02 | -3.42 | BROWNE_HCMV_INFECTION_30MIN_UP | MSigDB lists | BROWNE_HCMV_INFECTION_30MIN_UP | 52 | 13 | 17758 | 2588 |
COL6A2,CASK,PTK7,ZFP36,COL6A1,EGR3,APBA2,FOS,IL10RB,RHOB,CAMK2G,DUSP1,SOCS3 |
| 3.273e-02 | -3.42 | KEGG_ARGININE_AND_PROLINE_METABOLISM | MSigDB lists | KEGG_ARGININE_AND_PROLINE_METABOLISM | 52 | 13 | 17758 | 2588 |
PRODH,ALDH2,LAP3,P4HA2,P4HA3,SAT1,ASL,MAOA,ALDH7A1,GOT1,OAT,SAT2,ALDH3A2 |
| 3.276e-02 | -3.42 | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN | 182 | 36 | 17758 | 2588 |
KLF2,RECQL,LFNG,RPS6KA1,ATP8A1,CNOT8,CD82,INPP5D,IL27RA,TGOLN2,CCDC92,VASP,CD22,FXYD5,USP1,ZMYM1,RASGRP1,RNF169,ERMAP,NUB1,GALNT7,POLD3,PRIM1,NAAA,BTG1,SERTAD2,JAK1,STAT6,DCK,RIN3,NMI,PGM2L1,TMOD2,RPL22,ST3GAL1,AHR |
| 3.276e-02 | -3.42 | GSE27786_LSK_VS_NKCELL_UP | MSigDB lists | GSE27786_LSK_VS_NKCELL_UP | 182 | 36 | 17758 | 2588 |
NUDT6,PAX6,ST14,CAMKK1,FLYWCH2,FLOT1,TRIB2,NUDT12,SSX2IP,E2F7,UBE2T,TSPAN6,PHTF1,NR2C1,WBP5,TUBA4A,TDP1,MLEC,WNT10B,CCDC34,TNFAIP8L1,CCNF,VCP,PRDX4,PEX5,CASP7,ITGA7,WDR19,HAGHL,CDCA7L,BMP1,VSIG10,MLKL,NDE1,NCAPG2,TBC1D4 |
| 3.276e-02 | -3.42 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | 182 | 36 | 17758 | 2588 |
PNISR,TRIP10,AASS,CPT2,ATP8A1,CD82,PNPLA2,BTN3A1,DHRS3,PIGL,MAP1LC3B,CYP39A1,RSAD1,SCML1,DAPK2,PRICKLE3,BCL6,DRAM1,CD70,RFX5,NFU1,TFG,MYLIP,TIAM1,DUSP1,TGIF1,NR3C1,BNIP3L,PARP4,SLC11A2,C18orf8,GLCE,HLF,RBM47,CSF1,NR4A2 |
| 3.276e-02 | -3.42 | GSE3982_EOSINOPHIL_VS_MAC_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAC_UP | 182 | 36 | 17758 | 2588 |
PLA2G4A,ACACB,GOLIM4,REPS2,NLRX1,AKAP17A,KBTBD11,ARHGEF40,HPCAL4,PRRG4,ADD3,PPP1R10,FAM13B,SLC44A1,KLF3,ZDHHC13,GAD1,MYT1,CTDSP2,DLGAP1,TACC1,SYNE2,CYFIP2,FOS,CDK5R1,JAK1,WIPI1,RIN3,PNPLA6,PRDM5,ZDHHC7,NR4A2,PDPR,GAB1,JARID2,CTDSP1 |
| 3.280e-02 | -3.42 | lipid transport | biological process | GO:0006869 | 236 | 46 | 16441 | 2455 |
PLA2G4A,PRKAA2,ACACB,CPT2,ATP9A,ATP8A1,APOO,ABCG4,P2RX7,ANO9,SLC27A6,OSBPL3,KCNN4,FABP6,ABCA2,ATP8B1,SORL1,ABCD1,ACSL4,OSBPL7,ANO4,GM2A,NCOA2,SOAT1,FZD4,ANO6,VPS4B,PPARA,NPC2,ATP8B3,ESYT1,PCTP,CPTP,SPNS3,ATP10D,OSBPL2,LDLRAP1,PRKAG2,TMEM30A,MFSD2A,SLC27A1,PITPNA,ABCA1,APOL2,ESYT2,ABCG1 |
| 3.284e-02 | -3.42 | TCGA_GLIOBLASTOMA_COPY_NUMBER_UP | MSigDB lists | TCGA_GLIOBLASTOMA_COPY_NUMBER_UP | 68 | 16 | 17758 | 2588 |
PLEKHA6,FAM133B,SAMD9,AKAP3,GOLT1A,RHOB,EGFR,B4GALNT1,SOX13,LRRN2,RDH14,PIK3CA,PIK3C2B,GEN1,HIPK3,CTDSP2 |
| 3.284e-02 | -3.42 | chr1p22 | MSigDB lists | chr1p22 | 68 | 16 | 17758 | 2588 |
PGM1,MCOLN3,EPHX4,SSX2IP,SLC44A3,BCL10,SYDE2,BCAR3,DDAH1,KIAA1107,CYR61,LMO4,GFI1,ODF2L,WDR63,FAM69A |
| 3.284e-02 | -3.42 | KEGG_VIRAL_MYOCARDITIS | MSigDB lists | KEGG_VIRAL_MYOCARDITIS | 68 | 16 | 17758 | 2588 |
CASP3,CD55,HLA-E,HLA-F,CASP9,CD40,DAG1,HLA-A,ICAM1,CCND1,RAC2,HLA-B,FYN,HLA-C,MYH14,SGCB |
| 3.289e-02 | -3.41 | epithelial to mesenchymal transition | biological process | GO:0001837 | 56 | 14 | 16441 | 2455 |
EPB41L5,BMP2,TGFBR3,CTNNB1,FGFR2,BMP7,S100A4,SOX9,FAM83D,ADAM15,TGFBR1,EFNA1,LOXL2,FAM101B |
| 3.289e-02 | -3.41 | positive regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001244 | 56 | 14 | 16441 | 2455 |
TP73,SIRT1,SOD1,NKX3-1,BMF,DNM1L,TP53,BAX,PLEKHF1,BUB1,BCL2L1,SEPT4,PRKRA,BCAP31 |
| 3.291e-02 | -3.41 | Activation of NF-kappaB in B cells | REACTOME pathways | R-HSA-1169091 | 66 | 16 | 8202 | 1235 |
PSMB4,NFKBIE,PSME2,PSMD7,PSMD10,CUL1,PSME1,PSMA4,BCL10,PSMD1,PSMD3,PSMC2,NFKBIA,MAP3K7,PSMC1,PSMA5 |
| 3.291e-02 | -3.41 | receptor signaling protein tyrosine kinase activity | molecular function | GO:0004716 | 9 | 4 | 16491 | 2452 |
ERBB2,INSR,SYK,EGFR |
| 3.291e-02 | -3.41 | carbon-nitrogen lyase activity | molecular function | GO:0016840 | 9 | 4 | 16491 | 2452 |
APMAP,HAL,ASL,SRR |
| 3.291e-02 | -3.41 | G-protein coupled glutamate receptor binding | molecular function | GO:0035256 | 9 | 4 | 16491 | 2452 |
CALM3,CALM2,CABP1,CALM1 |
| 3.291e-02 | -3.41 | histone serine kinase activity | molecular function | GO:0035174 | 9 | 4 | 16491 | 2452 |
PRKAA2,AURKA,AURKB,PRKAA1 |
| 3.291e-02 | -3.41 | natural killer cell lectin-like receptor binding | molecular function | GO:0046703 | 9 | 4 | 16491 | 2452 |
ULBP2,HLA-E,MICB,RAET1L |
| 3.291e-02 | -3.41 | cytidylyltransferase activity | molecular function | GO:0070567 | 9 | 4 | 16491 | 2452 |
CMAS,NANS,CDS2,CDS1 |
| 3.291e-02 | -3.41 | phosphatidylinositol 3-kinase regulatory subunit binding | molecular function | GO:0036312 | 9 | 4 | 16491 | 2452 |
DAB2IP,PIK3AP1,PIK3R1,DNM2 |
| 3.295e-02 | -3.41 | neurexin family protein binding | molecular function | GO:0042043 | 13 | 5 | 16491 | 2452 |
CASK,SYTL4,CPE,SYTL3,SYTL2 |
| 3.295e-02 | -3.41 | misfolded protein binding | molecular function | GO:0051787 | 13 | 5 | 16491 | 2452 |
DNAJC10,F12,HDAC6,DNAJC3,DNAJB9 |
| 3.295e-02 | -3.41 | metalloaminopeptidase activity | molecular function | GO:0070006 | 13 | 5 | 16491 | 2452 |
ERAP1,LTA4H,RNPEP,ERAP2,METAP2 |
| 3.295e-02 | -3.41 | S100 protein binding | molecular function | GO:0044548 | 13 | 5 | 16491 | 2452 |
EZR,S100A11,IQGAP1,S100A6,ANXA11 |
| 3.298e-02 | -3.41 | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDM_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDM_UP | 188 | 37 | 17758 | 2588 |
TM2D2,ARHGEF7,INPP5D,ETNK1,C5orf30,DHX8,LGALS3BP,HMGXB4,XPR1,INPP5E,ENTPD4,DDHD2,MTMR10,TMEM51,SLC44A2,USP38,FAIM,MED22,MX1,PDGFC,SLC37A1,FIGNL1,SCRIB,UBAC1,ASB13,SESN1,C3orf58,RASA1,AHRR,NUDT16,MSL1,WFS1,DOLPP1,FAM3C,GLCCI1,SNX30,NR2C2 |
| 3.298e-02 | -3.41 | GSE13306_RA_VS_UNTREATED_TREG_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_TREG_DN | 188 | 37 | 17758 | 2588 |
GAS2L1,PLEKHG3,LASP1,CKAP2,GABRG2,IL18R1,SIRPA,EPDR1,HDAC9,TMCC3,TP73,DTX3L,PAK6,METTL7A,IMPAD1,FJX1,MITF,TMEM51,IL17RA,IGFBP2,OSTF1,CDKN2D,PHF20L1,MARK1,CELSR2,CDCA2,CBL,NEURL1B,GOLT1A,SERTAD2,COL13A1,SECTM1,C1orf21,NLRC5,PPM1H,ZDHHC7,GLCCI1 |
| 3.298e-02 | -3.41 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | 188 | 37 | 17758 | 2588 |
GRN,AASS,ATP8A1,CTSB,IL18,ITPR2,CDIPT,ERP29,LGALS3BP,SIPA1L2,STIM1,NEK2,AK3,TMEM37,ETHE1,PTPRE,SYK,SMAGP,KDELR1,SOAT1,PTPN18,ALDH2,SALL4,IFITM3,MPP1,PLAUR,CR2,RNPEP,NUCB1,FAM64A,ARRB1,CTSA,PLD1,PLOD3,RGS14,RPL22,MAP3K5 |
| 3.298e-02 | -3.41 | VEGF_A_UP.V1_UP | MSigDB lists | VEGF_A_UP.V1_UP | 188 | 37 | 17758 | 2588 |
MYL9,KIAA1462,NFKBIE,ENO2,FAM189A2,GRIK2,ZCCHC24,SDC4,ARL4C,TP53I11,MERTK,PHLDA1,ICAM1,PER2,RGS3,CABP1,MTMR11,NFKB2,CLIP2,SLC12A2,KANK3,APOBEC3G,MGAT5,EPHX1,P2RX4,AKAP3,OPTN,IRS2,PTPRJ,HTT,MATN2,DTX4,OVOL1,TMEM8B,GDF11,TRAF5,TLL2 |
| 3.298e-02 | -3.41 | GSE17721_LPS_VS_POLYIC_8H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_8H_BMDM_UP | 188 | 37 | 17758 | 2588 |
KIF3C,HSP90B1,SERPINE2,S100A11,DNAJC3,EPHA4,SOD2,PSMD10,CUL1,NOTUM,CHAC2,NCKAP1,NFAT5,APPBP2,MAGOHB,RAC2,ADRBK1,ZDHHC12,LMO4,ATP13A3,TRIM21,PDIA6,ABCC1,ATG4D,ZWINT,PARD3B,UXT,CCBL2,ARHGAP35,OSBPL2,RND3,ATXN7L3,DGAT2,ITGAV,CPEB2,HOXC13,NGEF |
| 3.303e-02 | -3.41 | CDC27 (cell division cycle 27) | protein interactions | 996 | 88 | 21 | 16036 | 2547 |
CASP3,TAF5,FOXM1,PTTG1,CDC20,AURKB,CCNB1,SH3KBP1,VCP,EPN3,RB1,CCNA2,HSF2,CDH1,CTNNB1,PTEN,NEK2,E2F1,CKS1B,MAD2L1BP,TTLL1 |
| 3.303e-02 | -3.41 | PSMD14 (proteasome 26S subunit, non-ATPase 14) | protein interactions | 10213 | 88 | 21 | 16036 | 2547 |
TXN,PSMB4,PSME2,AMFR,RNF11,PDIA5,PSMD7,PSMD10,PSME1,MCFD2,SPDL1,PSMA4,RAD23A,CCDC92,PSMD1,PSMD3,MITF,PSMC2,CCDC74B,PSMC1,PSMA5 |
| 3.306e-02 | -3.41 | negative regulation of nervous system development | biological process | GO:0051961 | 242 | 47 | 16441 | 2455 |
SEMA6B,PAX6,ADGRG1,CIT,SOX9,EPHA4,LRP4,TP53,PRKACA,TP73,CALR,SPP1,CTNNB1,PTEN,BMP7,KIAA0319,DUSP10,SORL1,DIXDC1,SEMA3G,NOTCH3,NTN1,WNT3A,GFI1,ITM2C,GPR161,SEMA3B,HES1,RHOA,ASPM,RAPGEF2,CDK5R1,ULK2,DPYSL3,IRX3,SEMA4D,PLK2,TRAF3IP1,NRG1,RAB29,GDF11,EFNA1,ARF6,SOX8,SEMA3A,CTDSP1,NGEF |
| 3.306e-02 | -3.41 | PFKL (phosphofructokinase, liver) | protein interactions | 5211 | 48 | 13 | 16036 | 2547 |
FAF2,PRDX3,TESK1,PFKL,PCBP3,PYGL,DMWD,FBXO6,PKM,HDAC6,EGFR,ZC3HC1,RAD21 |
| 3.306e-02 | -3.41 | PAPOLA (poly(A) polymerase alpha) | protein interactions | 10914 | 48 | 13 | 16036 | 2547 |
SIRT1,UFD1L,ZYX,ADRBK1,UGP2,FAM129B,CORO1C,PPP1CB,CSTF2,HDAC1,GNA11,LMNA,CORO1B |
| 3.306e-02 | -3.41 | BAD (BCL2-associated agonist of cell death) | protein interactions | 572 | 48 | 13 | 16036 | 2547 |
RPS6KA2,AKT1,RPS6KA1,PRKCI,BAX,STEAP3,BCL2L1,PPP1CA,PIM3,PIM1,PRKACA,RPS6KA3,VCP |
| 3.306e-02 | -3.41 | microtubule end | cellular component | GO:1990752 | 22 | 7 | 17570 | 2579 |
CAMSAP3,SLAIN2,KIF2C,CLIP2,ASPM,MYO5A,CKAP5 |
| 3.307e-02 | -3.41 | multi-organism reproductive behavior | biological process | GO:0044705 | 31 | 9 | 16441 | 2455 |
THRB,GRN,APLP2,PTEN,THRA,HEXB,GRIN1,UBE2Q1,DRD1 |
| 3.307e-02 | -3.41 | regulation of centrosome duplication | biological process | GO:0010824 | 31 | 9 | 16441 | 2455 |
CENPJ,PLK2,VPS4B,PLK4,XRCC3,CHMP4B,CCNF,NUBP1,GEN1 |
| 3.307e-02 | -3.41 | neuronal action potential | biological process | GO:0019228 | 31 | 9 | 16441 | 2455 |
P2RX4,SCN5A,KCNMB4,GRIK2,GPER1,MYH14,SCN2A,SCN3A,DRD1 |
| 3.307e-02 | -3.41 | negative regulation of microtubule polymerization or depolymerization | biological process | GO:0031111 | 31 | 9 | 16441 | 2455 |
GAS2L1,MID1IP1,CKAP2,TBCD,AURKA,AURKB,CCNB1,HDAC6,APC2 |
| 3.307e-02 | -3.41 | phospholipid dephosphorylation | biological process | GO:0046839 | 31 | 9 | 16441 | 2455 |
INPP5E,MTM1,INPPL1,PTEN,INPP5D,PLPP3,OCRL,TMEM55B,PLPPR4 |
| 3.312e-02 | -3.41 | IGLESIAS_E2F_TARGETS_UP | MSigDB lists | IGLESIAS_E2F_TARGETS_UP | 147 | 30 | 17758 | 2588 |
ANXA3,COL6A2,CDKN1C,S100A11,DSTN,SAT1,COL18A1,CTSZ,ZFAND5,NFIB,RHOB,LMNA,LCP1,SS18,APLP2,PCNA,SLC25A4,SCG2,NFKBIA,BAX,CD9,CKS1B,ACTA2,PKD2,SERPINB6,ACADM,NPTN,S100A13,S100A6,CRTAP |
| 3.312e-02 | -3.41 | WHITFIELD_CELL_CYCLE_S | MSigDB lists | WHITFIELD_CELL_CYCLE_S | 147 | 30 | 17758 | 2588 |
CDKN2AIP,GCLM,ZWINT,KIFC2,MAN1A2,OSGIN2,SLC25A27,COL7A1,PKMYT1,SRSF5,BBS2,RHPN1,FANCI,PRIM1,TOP2A,ARHGAP42,UBE2T,H1F0,CALD1,LMO4,REEP1,MITF,PHTF1,CDCA5,TRIM45,DONSON,USP1,EIF4EBP2,IFIT1,E2F8 |
| 3.317e-02 | -3.41 | GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN | 194 | 38 | 17758 | 2588 |
CCNE2,NDRG1,TAP1,ARFGEF1,IL18,MXD1,IER3,MDM1,CTSC,TPST1,TRIM21,PDIA6,SMAGP,CCDC88A,ABCC1,POU6F1,PCGF5,USP18,CD40,FAM109A,IFIT3,CASP4,SP4,ABR,STX3,TXK,AHRR,GABRD,ENPP1,SWAP70,RBL1,TIMM8A,CSF1,STAT1,LTBP2,CHPT1,SERPINB1,IRF1 |
| 3.317e-02 | -3.41 | GSE17721_0.5H_VS_8H_LPS_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_8H_LPS_BMDM_DN | 194 | 38 | 17758 | 2588 |
LZTFL1,RUNX2,DHPS,TAB3,CD82,MAN1A2,TAP1,SOD2,FAM91A1,SPTB,CARD10,TP73,RPS6KA2,SHC3,MITF,SNX16,MDFIC,WBP4,IL1RAP,CPD,POU6F1,PMPCB,GCA,HMGN5,VAMP3,PDK3,RAB3IP,TANC1,SPTLC2,PVRL2,ATXN7L3,ITPR1,PPP1CB,HDAC1,MAP3K5,RBM43,TRAF5,ARNT |
| 3.317e-02 | -3.41 | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | 194 | 38 | 17758 | 2588 |
LAMP1,LASP1,PPP1R12A,SSH1,NLRX1,CD63,ZCCHC24,ACTR8,MCTP2,ASL,DHX8,NOTCH2,CAMK1D,IL18R1,TIPRL,NFAT5,CHST2,ZFYVE16,ZNF432,PLCG2,ALPK1,NCAM1,PTPRE,APOBEC3G,SYK,NCOA2,ENPP4,ARAP2,TACC1,ITCH,FURIN,NKAIN1,YES1,ATP10D,GALNT3,DNM1L,RAB11FIP1,JARID2 |
| 3.317e-02 | -3.41 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | 194 | 38 | 17758 | 2588 |
GALK1,LGALS3,CKAP2,SERPINB9,KIF23,PDIA4,CKAP5,TOP2A,CNTRL,SIVA1,CAPG,PLK4,CKS1B,TUBG1,BUB1,IL10RB,CRTAP,S100A6,MX1,LOC81691,PGM1,IFITM3,SH3BGRL,CDC20,NUSAP1,ANLN,MRPS36,C4orf27,CDK1,CDKN2AIPNL,PAFAH1B3,CCDC6,DCK,SPAG7,STK39,CMPK2,ACOT7,XDH |
| 3.323e-02 | -3.40 | Neural Crest Differentiation | WikiPathways | WP2064 | 101 | 24 | 4455 | 729 |
HES1,MBP,HDAC11,SOX9,NOTCH2,HDAC6,ETS1,FGF19,RHOB,GBX2,HDAC9,CDH1,CTNNB1,FGFR2,BMP7,ZIC5,MITF,TFAP2A,HDAC1,TWIST1,NOTCH3,NFKB2,WNT3A,DVL2 |
| 3.325e-02 | -3.40 | HARRIS_HYPOXIA | MSigDB lists | HARRIS_HYPOXIA | 79 | 18 | 17758 | 2588 |
CD99,TXN,EPAS1,PLAUR,BIK,SAT1,BNIP3L,PDGFB,FOS,HDAC9,PGF,PTGS2,SPP1,PFKL,CDKN1B,IGFBP2,AK3,L1CAM |
| 3.325e-02 | -3.40 | LEIN_MIDBRAIN_MARKERS | MSigDB lists | LEIN_MIDBRAIN_MARKERS | 79 | 18 | 17758 | 2588 |
TSC22D3,DENND1B,EIF5A2,BAIAP3,SLC25A43,ARHGEF40,LTBP3,KCTD9,CD83,MAGED2,ENDOD1,CACHD1,STEAP2,ARRDC1,HMGA1,PANX2,AFAP1,CERS2 |
| 3.325e-02 | -3.40 | KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION | MSigDB lists | KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION | 79 | 18 | 17758 | 2588 |
MYO5B,ERBB2,RAB6A,EPHA1,CRABP2,PTGFRN,FBLN1,CYP39A1,RHOB,APPBP2,NRP2,CD8A,HSF2,MITF,ARNT,SEMA3B,PCSK5,CKS2 |
| 3.327e-02 | -3.40 | nef (p27) | protein interactions | 156110 | 763 | 140 | 16036 | 2547 |
LAMP1,CASP3,TXN,EPAS1,GATA3,IL18,CDIPT,OAT,MAP1LC3B,SH3KBP1,SLC9A7,PLS3,CALM2,ZYX,CTNNB1,IL6ST,ARL1,PIK3CA,DNM2,IRF2,PIK3CD,TUBA4A,LAMP2,TNIP1,SNTB2,ITCH,CASP9,EZR,PRKAR2B,SLC25A5,ARF4,SFXN1,PLCG1,LIMK1,AGFG2,MAPK13,PIK3C2B,ARF6,TRAF5,SLC31A2,RUNX2,GGA1,HLA-E,HLA-F,CALM3,SORBS3,TEC,TSPAN7,RB1,RAC2,SNX18,CD22,PAK2,HLA-C,CTSD,ULBP2,EEF1D,CALM1,PYGL,SRSF5,PKM,ELK1,NMT2,FAS,SEMA4D,NFKBIA,ITPR1,SH3BP4,B4GAT1,MAP3K5,SEMA3A,RARG,IRF1,GAS2L1,SORBS1,SLC2A4,NF2,UPF3B,IL15,IQGAP1,TP53,FTH1,BCL2L1,PCBP1,PRKACA,BCAP31,ZFYVE9,CCND1,CD46,HSPA2,AKT1,VPS4B,PRKCQ,CBL,ATP13A2,ATP1A1,FYN,DDOST,SLC9A6,STAT1,SLC27A1,ABCA1,PRKAR1A,WASF3,HSP90B1,CD63,ARHGEF7,TRAF2,SDC4,SELL,NKRF,NFAT5,SLC9A2,ICAM1,HLA-A,SNTA1,CD109,PTEN,ACTA2,MAP3K7,SPRY2,SYK,DUSP1,ADAM17,RHOA,PSMB4,IFITM3,PIK3R1,VAMP3,YES1,SNTB1,FOS,DDX23,CD83,HLA-B,CD8A,HNRNPH2,TBC1D4,CD81,OCLN |
| 3.327e-02 | -3.40 | TPR_1 | interpro domains | IPR001440 | 52 | 13 | 18293 | 2672 |
TTC21B,TTC8,TMTC1,RGPD5,PEX5,DNAJC3,TTC7A,IFIT1,TTC9,TMTC2,IFIT3,UNC45B,SPAG1 |
| 3.331e-02 | -3.40 | human chr11q21 | chromosome location | human chr11q21 | 36 | 8 | 26250 | 2805 |
ENDOD1,SESN3,JRKL,CCDC82,SLC36A4,MAML2,SMCO4,KDM4D |
| 3.332e-02 | -3.40 | digestive tract development | biological process | GO:0048565 | 138 | 29 | 16441 | 2455 |
EPB41L5,PDGFC,LGR4,THRA,ITGA6,RET,DCHS1,GATA3,NCKAP1,SAV1,CCNB1,NPHP3,FOXL1,EGFR,TP73,PDGFA,RB1,CYP1A1,FAT4,CTNNB1,FGFR2,GATA2,DACT1,MEGF8,SMO,KLF5,SHOX2,COBL,PCSK5 |
| 3.335e-02 | -3.40 | POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION | MSigDB lists | POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION | 124 | 26 | 17758 | 2588 |
MAP3K3,CDKN2AIP,TAOK2,CXXC5,RHOA,CDKN1C,RIPK2,LITAF,NOTCH2,CD40,SLC20A1,BCL10,TSPAN6,PLK2,SECTM1,IL31RA,NOD2,ZDHHC13,CANT1,SLC44A2,CITED2,TFG,F2R,TRAF5,NDFIP1,EEF1D |
| 3.338e-02 | -3.40 | respiratory system development | biological process | GO:0060541 | 207 | 41 | 16441 | 2455 |
KLF2,GRHL2,EPAS1,TMTC3,THRA,MAN1A2,SOX9,CTSZ,GPSM2,SIX4,PDGFA,TNS3,ITGA3,CTNNB1,CTGF,GPC3,ALDH1A3,TMBIM6,PPP1CA,PDE4D,MYT1,SPRY2,THRB,SPEF2,ADAMTS2,HES1,ASXL1,RC3H2,SAV1,NPHP3,DAG1,NFIB,CRISPLD2,HS6ST1,FGFR2,PTK7,FGF18,PLOD3,LTA4H,RARG,FOXA1 |
| 3.338e-02 | -3.40 | carnitine shuttle | biological process | GO:0006853 | 9 | 4 | 16441 | 2455 |
PRKAA2,ACACB,PRKAG2,CPT2 |
| 3.338e-02 | -3.40 | mitotic spindle elongation | biological process | GO:0000022 | 9 | 4 | 16441 | 2455 |
KIF23,RACGAP1,AURKB,PRC1 |
| 3.338e-02 | -3.40 | positive regulation of defense response to bacterium | biological process | GO:1900426 | 9 | 4 | 16441 | 2455 |
KLK7,KLK5,F2RL1,NOD2 |
| 3.338e-02 | -3.40 | regulation of transposition | biological process | GO:0010528 | 9 | 4 | 16441 | 2455 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G |
| 3.338e-02 | -3.40 | positive regulation of fatty acid beta-oxidation | biological process | GO:0032000 | 9 | 4 | 16441 | 2455 |
IRS2,TWIST1,PLIN5,PPARA |
| 3.338e-02 | -3.40 | regulation of cell communication by electrical coupling involved in cardiac conduction | biological process | GO:1901844 | 9 | 4 | 16441 | 2455 |
CALM3,CALM2,PDE4D,CALM1 |
| 3.338e-02 | -3.40 | heparin metabolic process | biological process | GO:0030202 | 9 | 4 | 16441 | 2455 |
NDST3,XYLT2,GLCE,CSGALNACT1 |
| 3.338e-02 | -3.40 | activation of anaphase-promoting complex activity | biological process | GO:0051488 | 9 | 4 | 16441 | 2455 |
PLK1,UBE2C,PTEN,CDC20 |
| 3.338e-02 | -3.40 | negative regulation of transposition | biological process | GO:0010529 | 9 | 4 | 16441 | 2455 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G |
| 3.338e-02 | -3.40 | arginine catabolic process | biological process | GO:0006527 | 9 | 4 | 16441 | 2455 |
DDAH1,OAT,ASL,FAH |
| 3.344e-02 | -3.40 | Polo-like kinase signaling events in the cell cycle | Pathway Interaction DB | plk_pathway | 4 | 3 | 2227 | 480 |
PLK1,PLK2,PLK4 |
| 3.351e-02 | -3.40 | positive regulation of steroid biosynthetic process | biological process | GO:0010893 | 13 | 5 | 16441 | 2455 |
IGF1R,POR,PRKAA1,ABCG1,SEC14L2 |
| 3.351e-02 | -3.40 | trophoblast giant cell differentiation | biological process | GO:0060707 | 13 | 5 | 16441 | 2455 |
E2F7,E2F8,SOCS3,MDFI,PLK4 |
| 3.351e-02 | -3.40 | embryonic skeletal joint morphogenesis | biological process | GO:0060272 | 13 | 5 | 16441 | 2455 |
OSR2,CTNNB1,OSR1,SHOX2,BMP7 |
| 3.351e-02 | -3.40 | negative regulation of leukocyte mediated cytotoxicity | biological process | GO:0001911 | 13 | 5 | 16441 | 2455 |
HLA-B,HLA-E,SERPINB9,HLA-A,TAP1 |
| 3.351e-02 | -3.40 | GDP metabolic process | biological process | GO:0046710 | 13 | 5 | 16441 | 2455 |
CASK,DLG3,MPP1,DLG1,MPP2 |
| 3.351e-02 | -3.40 | negative regulation of macrophage derived foam cell differentiation | biological process | GO:0010745 | 13 | 5 | 16441 | 2455 |
ITGAV,ABCA1,NFKBIA,ABCG1,PPARA |
| 3.351e-02 | -3.40 | regulation of cAMP-dependent protein kinase activity | biological process | GO:2000479 | 13 | 5 | 16441 | 2455 |
SIRT1,PRKAR2B,RAPGEF2,PKIA,PRKAR1A |
| 3.351e-02 | -3.40 | positive regulation of glycolytic process | biological process | GO:0045821 | 13 | 5 | 16441 | 2455 |
PRKAA2,P2RX7,INSR,ARNT,PRKAA1 |
| 3.351e-02 | -3.40 | ether metabolic process | biological process | GO:0018904 | 13 | 5 | 16441 | 2455 |
TXN,FAR2,FAR1,TMEM86B,AGPS |
| 3.351e-02 | -3.40 | regulation of cell communication by electrical coupling | biological process | GO:0010649 | 13 | 5 | 16441 | 2455 |
CALM3,CALM2,PDE4D,CABP1,CALM1 |
| 3.351e-02 | -3.40 | attachment of spindle microtubules to kinetochore | biological process | GO:0008608 | 13 | 5 | 16441 | 2455 |
RB1,AURKB,CENPE,SGOL1,NDC80 |
| 3.351e-02 | -3.40 | protein autoprocessing | biological process | GO:0016540 | 13 | 5 | 16441 | 2455 |
CAPN2,KLK6,F12,CTSV,CAPN1 |
| 3.351e-02 | -3.40 | protein localization to chromosome, centromeric region | biological process | GO:0071459 | 13 | 5 | 16441 | 2455 |
RB1,AURKB,CENPA,SPDL1,CDK1 |
| 3.351e-02 | -3.40 | Glycerolipid metabolism | KEGG pathways | hsa00561 | 59 | 15 | 6908 | 1076 |
DGKH,ALDH2,AGPAT2,PLPP3,PNPLA2,DGKQ,DGKA,DGAT2,AKR1B1,ALDH7A1,GLA,LPIN3,DGKG,ALDH3A2,DGKE |
| 3.351e-02 | -3.40 | Glycerolipid metabolism | KEGG pathways | ko00561 | 59 | 15 | 6908 | 1076 |
DGKH,ALDH2,AGPAT2,PLPP3,PNPLA2,DGKQ,DGKA,DGAT2,AKR1B1,ALDH7A1,GLA,LPIN3,DGKG,ALDH3A2,DGKE |
| 3.353e-02 | -3.40 | PTMA (prothymosin, alpha) | protein interactions | 5757 | 83 | 20 | 16036 | 2547 |
CASP3,PSRC1,CDK17,PSME2,DSTN,CAPNS1,CCNB1,CDK1,PDIA4,CAPN2,CCNA2,CASP7,PCNA,STK26,RANBP1,PAPSS1,HDAC1,KPNA2,ISOC1,CTH |
| 3.358e-02 | -3.39 | JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | MSigDB lists | JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | 218 | 42 | 17758 | 2588 |
KLF2,LGALS3,CTSB,BLVRB,EPHA4,ARL4C,KCTD12,IL13RA1,RBP7,ETS1,FAM46C,DENND2D,CXCL16,TGFBR3,CALD1,PASK,SGK1,FAM102A,CTTN,MARCH2,RCAN3,CITED2,MYBL1,CDKN2D,ANKRD9,RASGRP1,CYP1B1,SULF2,SNTB2,CYP4F3,CRISPLD2,CDK5R1,STK17A,GABARAPL1,CD8A,LDLRAP1,SERPINA1,SECTM1,TMC5,TOB1,PCSK5,DOCK9 |
| 3.358e-02 | -3.39 | V$CDPCR3HD_01 | MSigDB lists | V$CDPCR3HD_01 | 218 | 42 | 17758 | 2588 |
IL15,TAB3,POC1B,EGR3,MGAT5B,TRIB2,GNB2,HOXB2,MECOM,PDCD10,CTGF,NPNT,DPYSL2,BHLHE41,LHX6,STEAP2,TWIST1,HEXIM2,DLG3,OSBPL7,MYT1,BTBD3,CCDC88A,C9orf9,TUBA4A,RASGRF1,TMTC2,NFIB,NIN,NFIX,BTG1,FYN,ITGA7,C1orf21,PLA2G15,NXPH4,NRG1,SERPINI1,DRP2,NR3C2,COL16A1,E2F8 |
| 3.360e-02 | -3.39 | V$HSF2_01 | MSigDB lists | V$HSF2_01 | 236 | 45 | 17758 | 2588 |
IER5L,ST13,CACNA2D2,EGR3,MORF4L2,VASH1,PDGFB,BCAP31,SPTB,SIX4,CHST2,ZNF212,IRF2BPL,SHC3,TSPAN6,BCL6,SRP54,KNTC1,CACNA1D,GAD1,RIMS2,DUSP1,ADAMTS2,TGIF1,TRIM8,LAP3,BCL9,KDM3A,PNKD,FOS,LHFPL2,CDK5R1,GIGYF1,RASGRP2,HLA-B,COL13A1,MAP2,NR4A3,FHL1,COL16A1,ACOT7,CMTM4,JARID2,HS6ST3,NR2C2 |
| 3.361e-02 | -3.39 | Estrogen signaling pathway | WikiPathways | WP712 | 20 | 7 | 4455 | 729 |
GNAS,GPER1,AKT1,ELK1,FOS,PRKACA,PIK3CA |
| 3.361e-02 | -3.39 | V$AP3_Q6 | MSigDB lists | V$AP3_Q6 | 230 | 44 | 17758 | 2588 |
ARHGAP11A,NCKAP5,RBM24,HOXB7,RALBP1,ATP6V1E2,IRX4,TESK2,HMGN3,RND1,NEO1,CDK14,WWP2,CD109,FOXP2,SCNN1A,CALD1,ICAM5,KCNK5,LHX6,SLC44A1,FAM63A,GFI1,GAD1,TGIF1,CASK,TRIM8,TNIP1,NPC2,SAV1,RNF19B,EBF2,NMT2,EDNRA,CXXC4,MYLK,CTNND1,SP6,SPRY4,LEMD1,GEN1,AHR,LRRC57,JARID2 |
| 3.363e-02 | -3.39 | regulation of coenzyme metabolic process | biological process | GO:0051196 | 51 | 13 | 16441 | 2455 |
PRKAA2,INSR,PRKAG2,PRKAA1,PPARA,TP53,P2RX7,PDK3,PDPR,ARNT,PDHX,DLAT,IER3 |
| 3.363e-02 | -3.39 | regulation of cofactor metabolic process | biological process | GO:0051193 | 51 | 13 | 16441 | 2455 |
PRKAA2,INSR,PRKAG2,PRKAA1,PPARA,TP53,P2RX7,PDK3,PDPR,ARNT,PDHX,DLAT,IER3 |
| 3.367e-02 | -3.39 | chordoma | COSMIC cancer mutations | chordoma | 27 | 8 | 17775 | 2585 |
SS18,CTNNB1,PTEN,PIK3CA,TP53,FLT3,IDH1,EGFR |
| 3.368e-02 | -3.39 | Synthesis and Degradation of Ketone Bodies | WikiPathways | WP311 | 5 | 3 | 4455 | 729 |
HMGCL,OXCT1,BDH1 |
| 3.378e-02 | -3.39 | REGULATION_OF_PHOSPHORYLATION | MSigDB lists | REGULATION_OF_PHOSPHORYLATION | 47 | 12 | 17758 | 2588 |
CCND1,CDKN2C,NF2,IL31RA,CDKN1B,RAD17,CD81,BARD1,CDKN2D,EGFR,CCDC88A,BCL10 |
| 3.378e-02 | -3.39 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | MSigDB lists | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | 47 | 12 | 17758 | 2588 |
THRB,NR3C1,NR1D2,NRBF2,NR4A1,THRA,PPARA,NR4A3,NR4A2,NR3C2,RARG,NRBP1 |
| 3.378e-02 | -3.39 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | MSigDB lists | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | 47 | 12 | 17758 | 2588 |
CHSY3,B3GALT6,AGRN,HSPG2,GPC3,SDC4,HEXB,CSGALNACT1,DSE,ARSB,SDC1,CHPF |
| 3.378e-02 | -3.39 | REACTOME_PI_METABOLISM | MSigDB lists | REACTOME_PI_METABOLISM | 47 | 12 | 17758 | 2588 |
MTM1,PI4K2B,INPP5E,INPPL1,PTEN,OCRL,PIK3R1,INPP4B,PIK3CA,PIK3C2B,PIK3CD,PIKFYVE |
| 3.378e-02 | -3.39 | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | MSigDB lists | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | 47 | 12 | 17758 | 2588 |
PSMD1,PSMB4,PSME2,PSMD3,PSMC2,TP53,PSMD7,PSMD10,PSME1,PSMC1,PSMA4,PSMA5 |
| 3.378e-02 | -3.39 | TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 47 | 12 | 17758 | 2588 |
ACVR1,TGFBR3,FNTA,CDKN1C,ACVRL1,RGMB,GDF15,TGFBR1,LTBP2,MAP3K7,CITED2,ZFYVE9 |
| 3.378e-02 | -3.39 | TUBULIN_BINDING | MSigDB lists | TUBULIN_BINDING | 47 | 12 | 17758 | 2588 |
KIF5B,SUN2,HTT,CENPJ,UXT,TUBGCP6,RACGAP1,NDE1,CCDC88A,ATG4A,GABARAPL1,ATG4D |
| 3.378e-02 | -3.39 | DELACROIX_RAR_TARGETS_UP | MSigDB lists | DELACROIX_RAR_TARGETS_UP | 47 | 12 | 17758 | 2588 |
PRSS8,CTGF,FGF18,SAT1,AOX1,TNFRSF12A,PRSS22,HMGA1,CRABP2,DHRS3,PLEKHB1,DUSP1 |
| 3.378e-02 | -3.39 | MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_6 | MSigDB lists | MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_6 | 47 | 12 | 17758 | 2588 |
INPPL1,PCNA,ETS2,TUBB4B,MBNL3,GRIN1,WHSC1,MAPK4,ITPR2,ITPR3,PLCB2,CTDSP1 |
| 3.380e-02 | -3.39 | plasma membrane protein complex | cellular component | GO:0098797 | 510 | 90 | 17570 | 2579 |
CASP3,ACVR1,SORBS1,GRIK2,CACNA2D2,IL13RA1,APC2,CACNB4,ABCD4,TGFBR3,CTNNB1,CDH1,NPNT,IL6ST,DLG1,ABCA2,KCNS3,CTTN,PDE4D,SCN2A,DLG3,FLOT2,IL10RB,HSPA2,GM2A,SCN3A,SGCE,KCNIP3,ACVR1C,SNTB2,UTRN,ATP1B1,CD40,CBL,ALCAM,DAG1,KCNMB4,ATP1A1,ABHD12,KCNK1,CORO1C,TRAF5,SCN5A,HLA-E,ITGA6,HLA-F,TRAF2,LRP4,GNAL,EPS8,FLOT1,TGFBR1,CNTNAP2,KCNC4,ITGA2B,HLA-A,NEO1,BMP2,SNTA1,ITGA3,IRAK1,NOXA1,ITGB8,MAGEE1,KCNN4,HLA-C,CACNA1D,SGCB,SYK,GRIN1,SNTB1,GNA11,EGFR,FAS,BCL10,CNTNAP1,GNAS,HLA-B,CD8A,RGS9,INSR,LDLRAP1,COL13A1,ITGA7,NETO2,OSMR,ARRB1,GRIN2D,ATP1B3,ITGAV |
| 3.383e-02 | -3.39 | TMEM171 (transmembrane protein 171) | protein interactions | 134285 | 53 | 14 | 16036 | 2547 |
SLC25A24,GPRC5B,MOSPD2,CKAP2,ITCH,KDELR3,ADIPOR1,KNTC1,SLC7A2,CHPT1,TTYH3,TPCN1,CMTM4,OCLN |
| 3.383e-02 | -3.39 | COMMD1 (copper metabolism (Murr1) domain containing 1) | protein interactions | 150684 | 53 | 14 | 16036 | 2547 |
SPP1,SOD1,AKT1,ATP7B,CUL4B,NFKBIA,XIAP,SGK1,CUL1,COMMD5,NFKB2,SLC12A2,BARD1,VCP |
| 3.383e-02 | -3.39 | TUBB6 (tubulin, beta 6 class V) | protein interactions | 84617 | 53 | 14 | 16036 | 2547 |
INPPL1,TUBB4B,SPRTN,IGSF8,CAMK1D,FBXO6,SAV1,NUCB2,ILK,CD81,PCBP1,ICAM1,EGFR,TUBA4A |
| 3.383e-02 | -3.39 | negative regulation of hydrolase activity | biological process | GO:0051346 | 404 | 74 | 16441 | 2455 |
SPRED1,PPP4R4,RPS6KA1,CAST,IQGAP1,PTTG1,ARFGEF1,XIAP,TP53,F11R,SYTL2,APLP2,FICD,DAB2IP,CRY2,IFIT1,DLG3,CDKN2D,CHP1,SIRT1,PPIF,CAMSAP3,TIMP2,BAG4,AKT1,PKMYT1,POR,NEIL1,PPP2R4,SERPINB6,SERPINI1,ARFGEF3,LMTK3,SORT1,FARP1,SERPINE2,TRAF2,SERPINB9,AIP,TIPRL,SH2D4A,SH3RF2,CD109,TIMP1,GPC3,CST3,PAK2,SORL1,TMBIM6,FNIP1,MAPK7,RAG1,SPRY2,TMED2,PLAUR,FURIN,COL7A1,LEPR,PLIN5,FAS,TIMP3,SERPINA1,HTT,SEMA4D,PRDX3,SPINT2,SH3BP4,ARRB1,SERPINB5,SERPINB1,CPEB2,IFI6,RPS6KA3,EGLN1 |
| 3.385e-02 | -3.39 | SFN (stratifin) | protein interactions | 2810 | 256 | 52 | 16036 | 2547 |
ARHGAP11A,LMO7,TNK1,FAM189A2,PPP1R2,DCAF7,KLC2,PPFIBP2,TP53,PKP2,KIF23,RHPN2,RACGAP1,ARHGEF16,HDAC9,KIF5B,WEE1,APLP2,ST5,RALGPS2,CYR61,ZFP36,MKRN3,OSBPL3,PAK2,BAX,PLK4,TRIM62,ING1,MARK1,AKT1,NR3C1,ITCH,PARD3B,RAB3IP,SAV1,CBL,CDC25C,BCAR1,CDK1,EGFR,MAP1B,IRS2,TNS4,MPRIP,RND3,SHROOM3,H1F0,SIPA1L1,SH3BP4,PIK3C2B,MAP3K5 |
| 3.389e-02 | -3.38 | core promoter sequence-specific DNA binding | molecular function | GO:0001046 | 94 | 21 | 16491 | 2452 |
SIRT1,RUNX2,PAX6,SUZ12,SOX9,TP53,GATA3,FOS,GBX2,TAF1B,NR1D2,STAT6,MITF,NR4A3,TFAP2A,STAT1,NLRC5,H2AFY,NR4A2,IRF7,SOX8 |
| 3.400e-02 | -3.38 | condensed chromosome | cellular component | GO:0000793 | 193 | 38 | 17570 | 2579 |
SPC25,HJURP,NDC80,ERCC6L,NUF2,KIF2C,CCNB1,SPDL1,CENPN,TOP2A,ADD3,RGS12,KMT5C,NEK2,TUBG1,H2AFY,BUB1,KNTC1,NUP85,HSPA2,SMC4,PLK1,REC8,SUN2,CENPA,ZWINT,CENPC,SEPT6,AURKB,SKA1,DCTN6,CDCA5,AURKA,CENPE,NUP37,NDE1,SGOL1,RAD21 |
| 3.401e-02 | -3.38 | mating | biological process | GO:0007618 | 36 | 10 | 16441 | 2455 |
THRB,GRN,APLP2,SERPINE2,PTEN,THRA,HEXB,GRIN1,UBE2Q1,DRD1 |
| 3.401e-02 | -3.38 | organelle transport along microtubule | biological process | GO:0072384 | 36 | 10 | 16441 | 2455 |
KIF5B,KIF3C,HTT,UXT,KIF13A,RAB6A,NDE1,COPG1,RASGRP1,MAP1B |
| 3.401e-02 | -3.38 | neuron apoptotic process | biological process | GO:0051402 | 36 | 10 | 16441 | 2455 |
CASP3,RB1,GRIK2,HTT,TP53,BAX,ERBB3,BCL2L1,SCN2A,FAS |
| 3.401e-02 | -3.38 | positive regulation of bone mineralization | biological process | GO:0030501 | 36 | 10 | 16441 | 2455 |
BMP2,ACVR1,WNT10B,FAM20C,BMP7,ANO6,TFAP2A,P2RX7,OSR2,OSR1 |
| 3.401e-02 | -3.38 | protein kinase B signaling | biological process | GO:0043491 | 36 | 10 | 16441 | 2455 |
NKX3-1,AKT1,PTEN,AXL,SOX9,PIK3CA,PIK3C2B,CD40,ILK,MERTK |
| 3.404e-02 | -3.38 | SRC_UP.V1_DN | MSigDB lists | SRC_UP.V1_DN | 159 | 32 | 17758 | 2588 |
SEMA6B,NFKBIE,CAPN12,LFNG,PKP2,RACGAP1,CHAC2,HOXB2,RNF220,LYPD3,PLK4,IFIT1,ACSL4,SOAT1,KIAA1841,PTGER4,SPNS3,STK17B,MAP3K6,SCRN2,FRMD4B,ZNF628,RCBTB2,OTUD6B,SLC2A6,PCDH19,PIK3C2B,TMEM14A,COBL,E2F8,IFI6,CPPED1 |
| 3.405e-02 | -3.38 | REACTOME_SIGNALLING_TO_RAS | MSigDB lists | REACTOME_SIGNALLING_TO_RAS | 27 | 8 | 17758 | 2588 |
MAPKAPK2,RALB,MAPKAPK3,SHC3,MAPK13,MAPK11,CDK1,MAPK12 |
| 3.405e-02 | -3.38 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | MSigDB lists | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | 27 | 8 | 17758 | 2588 |
IRS2,JAK1,AKT1,STAT6,PIK3R1,PIK3CA,PIK3CD,JAK3 |
| 3.405e-02 | -3.38 | KEGG_HISTIDINE_METABOLISM | MSigDB lists | KEGG_HISTIDINE_METABOLISM | 27 | 8 | 17758 | 2588 |
ALDH3B1,ALDH2,ALDH1A3,HAL,MAOA,ALDH7A1,ALDH3A2,AMDHD1 |
| 3.405e-02 | -3.38 | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | MSigDB lists | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | 27 | 8 | 17758 | 2588 |
MDK,ADORA1,IGFBP6,IGFBP2,MEST,FOS,RIMS2,IGSF3 |
| 3.405e-02 | -3.38 | ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | MSigDB lists | ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 27 | 8 | 17758 | 2588 |
TAOK2,IRAK1,TRAF2,STRADB,MAP3K7,CARD10,PICK1,CCDC88A |
| 3.405e-02 | -3.38 | BIOCARTA_CREB_PATHWAY | MSigDB lists | BIOCARTA_CREB_PATHWAY | 27 | 8 | 17758 | 2588 |
GNAS,AKT1,RPS6KA1,PIK3R1,PIK3CA,PRKAR2B,CAMK2G,PRKAR1A |
| 3.412e-02 | -3.38 | V$XBP1_01 | MSigDB lists | V$XBP1_01 | 130 | 27 | 17758 | 2588 |
CASK,ARMCX3,HOXB7,SNTB2,ITCH,SRSF5,MORF4L2,TRIB2,TP53INP2,TSPAN7,PPP2R3A,PRDX4,PDIA4,CCND1,PPP1R10,HNRNPH2,ARL1,NR4A3,GYS1,ARFGAP3,PLEKHF1,GLA,PIM1,MANF,KIF12,KDELR1,SEMA3B |
| 3.412e-02 | -3.38 | V$PR_02 | MSigDB lists | V$PR_02 | 130 | 27 | 17758 | 2588 |
DOCK4,NCKAP5,MBP,ST13,ZNF395,CPEB4,ACBD3,ITGA6,DSTN,CALCRL,FBXO9,AKAP3,PDGFB,SDC1,ETS1,RANBP9,MAP1B,SCNN1A,RGS3,DOLPP1,ELF5,OPN3,BCL6,DUSP10,DLG3,SEMA3A,STK35 |
| 3.413e-02 | -3.38 | sex_cord-stromal_tumour | COSMIC cancer mutations | sex_cord-stromal_tumour | 42 | 11 | 17775 | 2585 |
GNAS,CDKN2C,NF2,CTNNB1,PTEN,PIK3R1,PIK3CA,TP53,IDH1,EGFR,PRKAR1A |
| 3.413e-02 | -3.38 | branching involved in ureteric bud morphogenesis | biological process | GO:0001658 | 46 | 12 | 16441 | 2455 |
BMP2,CTNNBIP1,FAT4,CTNNB1,NPNT,GPC3,DCHS1,SOX9,DLG1,PKD2,ILK,ADAMTS16 |
| 3.413e-02 | -3.38 | dendrite morphogenesis | biological process | GO:0048813 | 46 | 12 | 16441 | 2455 |
FYN,FARP1,CELSR2,PTEN,MAP2,FMN1,DACT1,LRP4,SLC11A2,BTBD3,SEMA3A,KLF7 |
| 3.415e-02 | -3.38 | response to UV | biological process | GO:0009411 | 127 | 27 | 16441 | 2455 |
SIRT1,DDB2,CASP3,AKT1,PBK,CUL4B,PIK3R1,CASP9,SPRTN,PRKAA1,UBE2A,TP53,AURKB,EGFR,SDF4,TP73,FECH,CCND1,PTGS2,PCNA,MSH2,BAX,USP1,ERCC2,SCARA3,CDKN2D,MSH6 |
| 3.415e-02 | -3.38 | embryonic limb morphogenesis | biological process | GO:0030326 | 127 | 27 | 16441 | 2455 |
CYP26B1,RUNX2,GRHL2,SALL4,LRP4,RAB23,OSR2,CRABP2,FZD6,MECOM,GNAS,CTNNB1,IMPAD1,BMP7,MEGF8,GPC3,HOXA9,FRAS1,TRAF3IP1,BAX,TFAP2A,HDAC1,TWIST1,ECE1,OSR1,SHOX2,RARG |
| 3.415e-02 | -3.38 | embryonic appendage morphogenesis | biological process | GO:0035113 | 127 | 27 | 16441 | 2455 |
CYP26B1,RUNX2,GRHL2,SALL4,LRP4,RAB23,OSR2,CRABP2,FZD6,MECOM,GNAS,CTNNB1,IMPAD1,BMP7,MEGF8,GPC3,HOXA9,FRAS1,TRAF3IP1,BAX,TFAP2A,HDAC1,TWIST1,ECE1,OSR1,SHOX2,RARG |
| 3.416e-02 | -3.38 | SLX4 (SLX4 structure-specific endonuclease subunit) | protein interactions | 84464 | 34 | 10 | 16036 | 2547 |
GID8,PLK1,DCAF10,PCNA,PSMB4,SPRTN,MSH2,LRRC1,VCP,MSH6 |
| 3.416e-02 | -3.38 | PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma) | protein interactions | 5294 | 34 | 10 | 16036 | 2547 |
PRKAA2,ADRBK1,IL6ST,UTRN,PDE4D,PIK3CD,GAB1,SYK,SEC14L2,GABARAPL1 |
| 3.416e-02 | -3.38 | HK2 (hexokinase 2) | protein interactions | 3099 | 34 | 10 | 16036 | 2547 |
SLC2A4,FNTA,PPME1,SEPT6,HEXB,PYGL,FBXO6,NUBP1,H2AFV,EGFR |
| 3.427e-02 | -3.37 | TGFB1 (transforming growth factor beta 1) | protein interactions | 7040 | 58 | 15 | 16036 | 2547 |
RMND5A,BMP2,LTBP1,FNTA,TGFBR3,ITGB8,CTGF,ACVRL1,VASN,TGFBR1,ITGAV,FBXO6,SLC35G2,LTBP3,NMT2 |
| 3.430e-02 | -3.37 | PTEN (phosphatase and tensin homolog) | protein interactions | 5728 | 141 | 31 | 16036 | 2547 |
CCNE2,TRIM8,PINK1,TRIM24,ENO2,CENPC,AKT1,SHARPIN,XIAP,TP53,PBX3,PKMYT1,CBL,TXNDC11,SLC9A3R2,MXD1,WWP2,NCOA3,CDH1,CTNNB1,LLGL2,PLPP3,HAGHL,PPP2R4,DLG1,WWP1,GPER1,PPP1CA,IFIH1,NDFIP1,RNF146 |
| 3.431e-02 | -3.37 | prostate gland development | biological process | GO:0030850 | 41 | 11 | 16441 | 2455 |
NKX3-1,IGF1R,CTNNB1,PTEN,FGFR2,SOX9,SERPINB5,HOXB13,RARG,AHR,FOXA1 |
| 3.431e-02 | -3.37 | regulation of meiotic cell cycle | biological process | GO:0051445 | 41 | 11 | 16441 | 2455 |
NPM2,CALR,RPS6KA2,INSR,ASPM,CDC20,MSH2,OVOL1,PRKACA,DUSP1,PRKAR1A |
| 3.431e-02 | -3.37 | positive regulation of cell-matrix adhesion | biological process | GO:0001954 | 41 | 11 | 16441 | 2455 |
EPB41L5,TSC1,PTPRJ,FMN1,CSF1,SDC4,UTRN,EPHA1,ILK,EMP2,COL16A1 |
| 3.432e-02 | -3.37 | MAP3K1 (mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase) | protein interactions | 4214 | 125 | 28 | 16036 | 2547 |
UFD1L,FAF2,RHOA,TNIP1,TRIM5,NR4A1,DNAJB2,TRAF2,CD82,UBASH3B,DCAF7,TP53,C6orf106,UBAC1,EPHA1,ZFAND5,GSTP1,RAD23A,RABEP2,STK38,NFKBIA,UBE2D2,DCUN1D1,CCDC69,ARRB1,ARHGAP4,DVL2,RAB3IL1 |
| 3.433e-02 | -3.37 | PDGF | pfam domains | PF00341 | 9 | 4 | 16629 | 2504 |
PDGFA,PGF,PDGFC,PDGFB |
| 3.433e-02 | -3.37 | Biotin_lipoyl | pfam domains | PF00364 | 9 | 4 | 16629 | 2504 |
ACACB,PDHX,DLAT,MCCC1 |
| 3.437e-02 | -3.37 | regulation of macromolecule metabolic process | biological process | GO:0060255 | 5698 | 891 | 16441 | 2455 |
TRIM24,IBTK,GRIK2,TRIM5,DNAJC3,HEXB,RET,XIAP,FBXO2,SMARCAL1,NRG2,IL18,MORF4L2,SNX9,BARD1,CARD10,PHF1,GRM5,ZNF275,TP73,NPM2,CALM2,CDKN2C,PSMD1,TGFBR3,KLF3,DNM2,CRY2,PPP1CA,PIK3CD,TIPARP,APOBEC3G,NEK4,VPS11,SMARCA2,TNIP1,UXT,SPRTN,TFAP2C,PRKAR2B,LOXL2,F12,RNF19B,ARF4,PIAS3,ENPP1,CARHSP1,PLCG1,CAMK2N2,ANKRD6,LIMK1,TRAF3IP1,NOD2,MAP3K11,HDAC1,SERPINB6,RNASEL,LSM14B,HSPB1,E2F8,GAB1,HOXC13,ZNF720,GGA1,NUAK1,TMTC3,ITGA6,SOX9,RAB23,LMNA,ELF3,MARCH8,TFAP4,FLII,RAC2,PAIP2B,MEGF8,FBXO7,NEK2,MAP3K9,USP38,USP1,MYDGF,NCAM1,MAPK7,MYLIP,NUP85,PHKG2,PPP6R1,MAPKAPK3,SALL4,STAT4,PYM1,FHL2,MYBL2,ELK1,ILK,TP53INP2,PSMA4,DCP2,NCOA3,FNTA,ETS2,HTT,SEMA4D,SETD3,AURKA,STK39,GDF11,CBX5,SERPINB1,ZNF502,NUP58,RPS6KA3,TMEM173,XDH,EGLN1,GRHL2,INPP5D,ACTR8,PTTG1,WDTC1,PRKACA,APC2,CCND1,ST5,CDH1,SP100,DACT1,DLG3,RASGEF1A,CDKN2D,MYT1,ETV4,RNF169,CAMSAP3,PSRC1,RIPK2,APOBEC3D,NRBF2,FZD4,HTATIP2,CDCA2,PXYLP1,GTF2A2,SNX12,ZNF618,EBF2,NFIX,IRS2,CCNB3,CORO1C,WFS1,WWTR1,RGS14,ARNT,MAPK12,FARP1,TAOK2,NKX3-1,TNRC6C,HSP90B1,RBM24,PARP14,CKAP2,ESRP1,TRAF2,SDC4,HABP4,FLOT1,GMCL1,CTSZ,PKN1,ZNF219,ETS1,GSTP1,NFAT5,TIPRL,HOXB2,ICAM1,NEO1,CTNNBIP1,DIRAS3,ZFX,PDCD10,ITGB8,IRAK1,CTSC,KNDC1,GPC3,MCF2L,CST3,BAX,TMBIM6,WWP1,ZNF230,MAPK11,RAG1,MED22,CRTAP,POU6F1,PLSCR1,BCL9,RAPGEF2,PIK3R1,EIF5A2,NUB1,GRIN1,PGBD1,ABLIM2,TXK,PITX2,BTG1,KIAA0141,ATXN7L3,NR1D2,ACVRL1,ZFP30,NR4A3,ITGAV,HMGA1,CENPE,NUP37,OSR1,CD81,USF2,SHOX2,SRSF9,FOXA1,SIGIRR,AGRN,EPAS1,CNOT8,CUL4B,EPHA4,SUDS3,ARFGEF1,LMCD1,NDRG2,NENF,HDAC6,PDGFB,SPTB,FANCI,TFAP2E,PCNA,NUP210,RPS6KA2,CTNNB1,NPNT,SHC3,IL6ST,PSMC2,MITF,ELF5,PASK,ABCA2,DUSP10,TNFRSF18,MYBL1,ZNF462,PLK1,THRB,PCGF5,CD55,KCNIP3,CELSR2,CITED4,CBX6,NFE2L1,C12orf65,EZR,EAF2,PRKRA,ZBTB7B,CDK1,VCP,OPTN,IRX3,KDM4D,KLF12,ZNF367,HOXA9,PRKCDBP,CTNND1,KLF11,KPNA2,TC2N,MAFF,PRKAA2,RUNX2,LMTK3,DNAJB2,UBASH3B,RASA2,PDCL,PSMD7,SORBS3,HES2,FBLN1,BMP2,RB1,DAZAP1,TIMP1,IGF1R,GATA2,PAK2,MDFIC,PIM1,WNT3A,PSMA5,USP31,RGMB,ZNF320,STRADB,SCRIB,EIF2AK1,TCF7,ZSCAN12,BCL2L13,CDK5R1,FOXD2,MAPKAPK2,CSF1,NLRC5,CDAN1,IFI6,CTBP1,USP43,RAD21,AVPI1,NF2,HOXB7,UPF3B,FOXM1,CTDSPL,TP53,ZNF28,P2RX7,ERBB2,RASGRP3,CCNL1,BAHD1,LPIN3,STIL,EMP2,BCAP31,SYTL2,PER2,RAD23A,IER3,TTC21B,PDGFA,KMT5C,LMO4,PPME1,LHX6,PLCG2,BCL6,CDH3,NOTCH3,OAS3,EGLN3,CTDSP2,DVL2,CTH,SIRT1,TIMP2,ERLEC1,TCEB2,AKT1,FIGNL1,CDC20,SERTAD3,ACO1,C3orf33,DAG1,MYPOP,ZNF628,DNAJC10,PTPRJ,IDE,RBL1,PSMD3,STK38,EFNA5,IRF7,ZBTB6,CNEP1R1,ZNF701,ARFGEF3,CTDSP1,PINK1,CPEB4,MACC1,CD63,TAB3,DAP,PSMD10,GTF3A,GDF15,HMGN3,NKRF,CRABP2,AIP,PARM1,SH2D4A,FZD6,PPP2R3A,GBX2,CD109,FOXP2,GTF2F2,TFAP2A,UBE2J1,SGK1,TRIM21,BUB1,HEXIM2,KLF9,SYK,CAMK2G,TLE6,DUSP1,WBP5,NFE2L3,HES1,RHOA,HMGN5,PSMB4,NR3C1,IFITM3,PLAUR,LITAF,PPARA,PRICKLE1,MAML2,COL7A1,FXR2,BBS2,MAPK8IP1,USP6,BCL10,CNOT2,BANK1,SERPINA1,TWSG1,ZNF214,CDCA7L,NMI,FGF18,E2F1,PPP2R3C,PKD2,NDFIP1,UBE2C,HIPK3,ZBTB33,PKIA,TXN,PPP4R4,ACVR1,SSH1,LGR4,TSC22D3,CUL1,GATA3,PSME1,CAMK1D,CCNB1,SEPT4,RIC1,PICK1,PAK6,HELZ2,CTGF,ZNF823,ZFP36,RGS3,IL31RA,FOSB,PIK3CA,IRF2,ZBTB18,ACVR1C,PBK,CASP9,CDYL,AGO4,PIF1,AURKB,SAV1,LDB2,POR,AHRR,HLF,AREG,PLK2,TBX1,PPP2R4,NKD1,PRDM5,EIF4EBP2,NFKBIZ,SERPINI1,MAPK13,SPRY4,F2RL1,TRAF5,LZTS1,DDX58,KLF2,INPPL1,CDKN1C,DGKQ,PRKAA1,AKAP17A,NOTCH2,APBA1,PSIP1,SH3RF2,MECOM,CALR,ITGA3,CYR61,BHLHE41,NECAB3,MSH2,DAPK1,SORL1,DLX4,ZNF117,EEF1D,RIMS2,SOCS5,TRAK2,EPB41L5,GFPT1,MMD,ZNF84,MFI2,CALM1,WHSC1,EPHA1,CYFIP2,KDM3A,NFIB,RASA1,FAS,AP1AR,SERTAD2,PRKAG2,PELI2,NAB2,TCEAL4,ARAP1,FAM83D,PIAS2,SFMBT1,NR4A2,SAMD8,ZBTB34,EFNA1,PER3,MAP3K5,IRF1,ELK4,SPRED1,FOXO6,TCF25,ARMCX3,DLGAP5,S100A11,THRA,RPS6KA1,IQGAP1,SUZ12,CAST,IRX4,EGR3,FLT3,CD46,APLP2,NOV,CCNA2,ZNF75D,FAM46A,RALB,CDKN1B,DAB2IP,PDE4D,OSBPL7,FLOT2,NR2C1,MED30,FOXJ2,DMTN,DRAP1,PRKCQ,SLC11A2,ATP1B1,RAD17,PKMYT1,PYGO1,CBL,H2AFV,SP4,FZD7,ZNF469,PRDM11,ZNF641,FYN,JAK1,PPP2R5A,STK26,NGFRAP1,KIAA1804,STAT1,PPP1CB,SLC27A1,KLF5,NRG1,NR3C2,CBX7,ATMIN,PRKAR1A,PCOLCE,DEPDC1,HERC5,PBX3,APOBEC3H,FGF19,TEAD3,SIX4,WWP2,SCML1,SNTA1,E2F7,RNF128,PTEN,SGK3,ATP8B1,ERCC2,ERBB3,CITED2,CNOT6L,MAP3K7,GFI1,SPRY2,TRIM62,MSH6,NCOA2,PDGFC,TGIF1,RASGRF1,CASK,TCFL5,TEF,VAMP3,FURIN,ZKSCAN2,YES1,FOS,GPLD1,CRTC2,CDK5RAP1,TIMP3,FGFR2,PRDX3,TBX18,RYK,SERPINB5,GRIN2D,GPER1,LRRK1,FZD5,CPEB2,ESPL1,USP16,RGMA,JARID2,CCNC,EMX1,CASP3,ST13,CRYM,CAMKK1,VARS2,TAF6L,COMMD5,ERP29,ZFYVE16,EPCAM,HSF2,GRHL1,ZCCHC12,SIVA1,PHTF1,DLG1,ASH2L,ARNT2,SLC39A10,RASGRP1,SP5,CYP1B1,SOD1,CXXC5,TRIM8,ASXL1,ASCL5,ITCH,USP18,SEC14L2,MDK,NEIL1,ZNF114,GPRC5B,MADD,TDRD7,IARS2,CAB39,ZNF165,SP6,APBA2,PSMC1,PPP2R5D,NR2C2,PPP1R2,PPP1R12A,ZNF395,SERPINE2,BVES,ETV5,ASB9,CALM3,TEC,PHLPP1,DUSP5,ZNF432,PRKCI,SUCO,EBF4,FNIP1,BRAT1,ZNF692,NPTN,C10orf54,RFX5,ACAD8,LRIF1,ETV7,CCDC88A,MDFI,HP1BP3,ELK3,HMG20B,PDE5A,RANBP9,EGFR,SOX13,FECH,GNAS,BCAR3,NUDT16,TSC1,ONECUT1,INSR,PLPP3,NFKBIA,DCUN1D1,YOD1,CTSA,JAK3,TOB1,RARG,KLF7,DRD1,PROM2,GAS2L1,CCNE2,SORBS1,PAX6,IL15,PSME2,HDAC11,SOD2,IL27RA,TDRKH,OSR2,PATL2,MXD1,SAP130,SS18,SVBP,ZNF687,SETDB2,FRYL,KIF14,SMO,ZBTB49,TWIST1,ECE1,EPB41L4B,APIP,NFKB2,F2R,HSPA2,UPF3A,FRS3,CHP1,CKS2,MAP3K3,SOAT1,ZNF525,BAG4,TAF5,GLO1,ERBB2IP,SNAPC2,DUSP4,CD40,CDC25C,MAP3K6,ARHGAP35,SOCS3,JADE1,HSF4,STAT6,PEX2,OVOL1,PTBP3,TLE1,SPTBN5,AKNA,PPP2R2D,CBX4,GLIS3,ANXA3,SORT1,ARHGEF11,SH3D19,SERPINB9,LRP4,MIER3,TGFBR1,AES,TRIB2,HMGXB4,HDAC9,ZNF212,IRF2BPL,TOP2A,CARD8,ADORA1,TAF1B,BMP7,MYCL,TOX2,ACTA2,CKS1B,H2AFY,BRD7,KANK2,MXD3,IQGAP3,DCAF6,ADAM17,WNT10B,NR4A1,GCLC,RC3H2,RGCC,MBNL3,RUNX3,TCEAL8,FOXL1,MPV17L2,LEMD2,CASP7,SWAP70,SPINT2,RAP2C,UBE2D2,TADA2B,ARRB1,HOXB13,SOX8,ZMIZ1,AHR,ABCG1,ZNF596 |
| 3.446e-02 | -3.37 | PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) | protein interactions | 5290 | 63 | 16 | 16036 | 2547 |
UFD1L,AKT1,PIK3R1,RASGRP3,VARS2,MRAS,CD40,CBL,PCBP1,SLC9A3R2,SH3KBP1,IRS2,APLP2,STAT1,SGK1,PDE4D |
| 3.451e-02 | -3.37 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN | 63 | 15 | 17758 | 2588 |
SORBS1,PROM1,CYB5R2,OXR1,ELF5,MYLK,FOSB,SERPINB5,ACTA2,MAOA,FOS,NFIB,ATP10D,MAMDC2,ELF3 |
| 3.451e-02 | -3.37 | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | 63 | 15 | 17758 | 2588 |
DOCK4,IL1R1,ZNF641,PLSCR4,ST13,IGFBP6,LGALS8,TMX4,CLIP4,SRSF5,DOCK11,CPE,TIAM1,CTDSP2,FRMD4B |
| 3.451e-02 | -3.37 | KYNG_DNA_DAMAGE_BY_4NQO_OR_UV | MSigDB lists | KYNG_DNA_DAMAGE_BY_4NQO_OR_UV | 63 | 15 | 17758 | 2588 |
IL1R1,ATP6V0B,BTG3,PCNA,PCDH1,PAFAH1B3,SEMA4D,KCNK1,SLC9A6,IRF2,TLE1,ARNT2,SLC31A2,IL18R1,DUSP5 |
| 3.452e-02 | -3.37 | BROWNE_HCMV_INFECTION_12HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_12HR_DN | 96 | 21 | 17758 | 2588 |
TRIM2,SSH1,ASXL1,FHL2,LDB2,DHRS3,NMT2,STK17A,FYN,ST5,NR1D2,AIM1,SIPA1L1,HMGCL,ERCC2,MAP3K5,ZMIZ1,UBE2C,MAST4,SERPINB1,TTLL1 |
| 3.452e-02 | -3.37 | chr22q12 | MSigDB lists | chr22q12 | 96 | 21 | 17758 | 2588 |
GAS2L1,SUN2,TMEM184B,NF2,GCAT,PPARA,CBX6,ZNRF3,PDGFB,KREMEN1,SLC35E4,SEC14L2,ASPHD2,RAC2,TIMP3,SEC14L4,FBXO7,NPTXR,CBX7,APOL2,MAFF |
| 3.454e-02 | -3.37 | ovary-sex_cord-stromal_tumour-granulosa_cell_tumour | COSMIC cancer mutations | ovary-sex_cord-stromal_tumour-granulosa_cell_tumour | 32 | 9 | 17775 | 2585 |
GNAS,CDKN2C,NF2,PTEN,PIK3R1,PIK3CA,TP53,IDH1,EGFR |
| 3.454e-02 | -3.37 | urinary_tract-bladder-carcinoma-adenocarcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-adenocarcinoma | 32 | 9 | 17775 | 2585 |
CTNNB1,AKT1,FGFR2,RET,PIK3CA,TP53,ERBB2,FLT3,EGFR |
| 3.454e-02 | -3.37 | granulosa_cell_tumour | COSMIC cancer mutations | granulosa_cell_tumour | 32 | 9 | 17775 | 2585 |
GNAS,CDKN2C,NF2,PTEN,PIK3R1,PIK3CA,TP53,IDH1,EGFR |
| 3.455e-02 | -3.37 | exocytosis | biological process | GO:0006887 | 314 | 59 | 16441 | 2455 |
DOC2A,ANXA3,CD63,HABP4,ARFGEF1,P2RX7,CALM3,LGI3,PLD2,SYTL4,PDGFB,ITGA2B,SDF4,SYTL2,PDGFA,CALM2,RAB15,ANK1,TIMP1,CDK16,GATA2,LLGL2,RIMS3,STEAP2,EXOC8,CD9,CPLX1,CADPS2,PIK3CD,RAB27B,S100A13,SYK,SYTL3,MYO5A,RASGRP1,RIMS2,TUBA4A,CHP1,LAMP2,SOD1,RAB3B,DMTN,CALM1,VAMP3,SCRIB,AKAP3,STX3,SCRN2,TRIM9,SERPINA1,RAB11FIP2,SYT7,RAB11FIP1,NR4A3,RAB31,PLD1,SYT13,TC2N,SNPH |
| 3.455e-02 | -3.37 | Molecules associated with elastic fibres | REACTOME pathways | R-HSA-2129379 | 31 | 9 | 8202 | 1235 |
BMP2,LTBP1,FBLN5,ITGB8,BMP7,ITGAV,LTBP2,FBLN1,LTBP3 |
| 3.456e-02 | -3.37 | Downregulation of ERBB2:ERBB3 signaling | REACTOME pathways | R-HSA-1358803 | 13 | 5 | 8202 | 1235 |
ERBB2,NRG2,NRG1,ERBB3,AKT1 |
| 3.456e-02 | -3.37 | Uptake and function of anthrax toxins | REACTOME pathways | R-HSA-5210891 | 13 | 5 | 8202 | 1235 |
CALM3,CALM2,ANTXR1,CALM1,FURIN |
| 3.458e-02 | -3.36 | proteasomal protein catabolic process | biological process | GO:0010498 | 332 | 62 | 16441 | 2455 |
FAF2,HSP90B1,CIT,DNAJB2,JKAMP,PSME2,PTTG1,PSMD7,FBXO2,CUL1,PSMD10,PSME1,FBXO6,CCNB1,DNAJB9,WWP2,RAD23A,PSMD1,KIF14,PSMC2,NEK2,FBXL14,UBE2J1,WWP1,USP38,USP1,STT3B,PSMA5,PLK1,SIRT1,UFD1L,SEC61B,ERLEC1,FBXL16,USP31,PSMB4,ITCH,AMFR,USP18,CDC20,UBE2A,RNF165,FBXO9,AURKB,CCNF,PSMA4,CDK1,VCP,USP6,TRIM9,DNAJC10,PSMD3,WFS1,WWTR1,AURKA,ARRB1,YOD1,UBE2C,PSMC1,USP16,FBXW5,USP43 |
| 3.460e-02 | -3.36 | SHIPP_DLBCL_CURED_VS_FATAL_DN | MSigDB lists | SHIPP_DLBCL_CURED_VS_FATAL_DN | 42 | 11 | 17758 | 2588 |
GNS,TGIF1,SLC25A13,STAT1,BTN3A2,TLE1,ABCD1,CITED2,CAMK2G,ZNF212,ABCG1 |
| 3.460e-02 | -3.36 | BIOCARTA_CHREBP2_PATHWAY | MSigDB lists | BIOCARTA_CHREBP2_PATHWAY | 42 | 11 | 17758 | 2588 |
PRKAA2,PRKAG2,PPP2R5A,PRKAA1,PPP2R4,PRKAR2B,PRKACA,PPP2R5D,PPP2R2D,PPP2R3A,PRKAR1A |
| 3.460e-02 | -3.36 | ONO_FOXP3_TARGETS_DN | MSigDB lists | ONO_FOXP3_TARGETS_DN | 42 | 11 | 17758 | 2588 |
TGFBR3,CCNA2,RUNX2,RBL1,E2F1,SELL,IL17RA,RUNX3,CCNF,SGOL1,CASP4 |
| 3.460e-02 | -3.36 | BIOCARTA_BIOPEPTIDES_PATHWAY | MSigDB lists | BIOCARTA_BIOPEPTIDES_PATHWAY | 42 | 11 | 17758 | 2588 |
CALM2,PLCG1,FYN,STAT4,STAT6,MYLK,CALM1,STAT1,CALM3,GNA11,CAMK2G |
| 3.460e-02 | -3.36 | REACTOME_PLC_BETA_MEDIATED_EVENTS | MSigDB lists | REACTOME_PLC_BETA_MEDIATED_EVENTS | 42 | 11 | 17758 | 2588 |
PLA2G4A,CALM2,ADRBK1,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PLCB2,PRKACA,PRKAR1A |
| 3.460e-02 | -3.36 | PID_BMP_PATHWAY | MSigDB lists | PID_BMP_PATHWAY | 42 | 11 | 17758 | 2588 |
BMP2,ZFYVE16,RGMB,BMP7,CTDSPL,XIAP,PPP1CA,MAP3K7,CTDSP2,CTDSP1,RGMA |
| 3.460e-02 | -3.36 | WNT3A (wingless-type MMTV integration site family, member 3A) | protein interactions | 89780 | 25 | 8 | 16036 | 2547 |
PPP2R5A,TRAF2,GPC3,DLG1,RYK,WNT3A,PPP2R5D,PPP2R2D |
| 3.460e-02 | -3.36 | HEY2 (hes-related family bHLH transcription factor with YRPW motif 2) | protein interactions | 23493 | 25 | 8 | 16036 | 2547 |
SIRT1,CASP3,HES1,PLSCR1,HTT,HDAC1,ARNT,HDAC9 |
| 3.460e-02 | -3.36 | RAC2 (ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)) | protein interactions | 5880 | 25 | 8 | 16036 | 2547 |
NOXA1,PAK2,CUL1,ARHGDIB,FBXO6,ICMT,CD81,DEF6 |
| 3.460e-02 | -3.36 | CARHSP1 (calcium regulated heat stable protein 1) | protein interactions | 23589 | 25 | 8 | 16036 | 2547 |
PIAS3,DAZAP1,AKT1,RPS6KA1,SGK1,PCBP1,HSPB1,SMN1 |
| 3.460e-02 | -3.36 | RNF130 (ring finger protein 130) | protein interactions | 55819 | 25 | 8 | 16036 | 2547 |
TSPAN18,MCOLN3,UBE2D2,UBE2Z,TGFBR1,NRG1,SCN2A,TSPAN17 |
| 3.460e-02 | -3.36 | HMOX1 (heme oxygenase 1) | protein interactions | 3162 | 25 | 8 | 16036 | 2547 |
UFD1L,UGT8,AKT1,BLVRB,ASL,NRG1,HLA-C,POR |
| 3.460e-02 | -3.36 | haematopoietic_and_lymphoid_tissue-axilla-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-axilla-lymphoid_neoplasm-mantle_cell_lymphoma | 37 | 10 | 17775 | 2585 |
DHDH,CCND1,RB1,FAT4,OGDHL,TP53,WHSC1,COL16A1,ZNF117,NIN |
| 3.460e-02 | -3.36 | haematopoietic_and_lymphoid_tissue-stomach-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-stomach-lymphoid_neoplasm-mantle_cell_lymphoma | 37 | 10 | 17775 | 2585 |
DHDH,CCND1,RB1,FAT4,OGDHL,TP53,WHSC1,COL16A1,ZNF117,NIN |
| 3.460e-02 | -3.36 | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-mantle_cell_lymphoma | 37 | 10 | 17775 | 2585 |
DHDH,CCND1,RB1,FAT4,OGDHL,TP53,WHSC1,COL16A1,ZNF117,NIN |
| 3.460e-02 | -3.36 | haematopoietic_and_lymphoid_tissue-tonsil-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-tonsil-lymphoid_neoplasm-mantle_cell_lymphoma | 37 | 10 | 17775 | 2585 |
DHDH,CCND1,RB1,FAT4,OGDHL,TP53,WHSC1,COL16A1,ZNF117,NIN |
| 3.460e-02 | -3.36 | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-mantle_cell_lymphoma | 37 | 10 | 17775 | 2585 |
DHDH,CCND1,RB1,FAT4,OGDHL,TP53,WHSC1,COL16A1,ZNF117,NIN |
| 3.460e-02 | -3.36 | haematopoietic_and_lymphoid_tissue-pharynx-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-pharynx-lymphoid_neoplasm-mantle_cell_lymphoma | 37 | 10 | 17775 | 2585 |
DHDH,CCND1,RB1,FAT4,OGDHL,TP53,WHSC1,COL16A1,ZNF117,NIN |
| 3.462e-02 | -3.36 | FA | pfam domains | PF08736 | 13 | 5 | 16629 | 2504 |
EPB41L5,EPB41L4B,FARP1,EPB41L4A,FARP2 |
| 3.464e-02 | -3.36 | Regulation of APC/C activators between G1/S and early anaphase | REACTOME pathways | R-HSA-176408 | 77 | 18 | 8202 | 1235 |
PLK1,PSMB4,PSME2,CDC20,PSMD7,CUL1,PSMD10,PSME1,CCNB1,CDK1,PSMA4,CCNA2,PSMD1,PSMD3,PSMC2,UBE2C,PSMC1,PSMA5 |
| 3.466e-02 | -3.36 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | 340 | 62 | 17758 | 2588 |
LAMP1,CCNI,GAA,SLC35D2,CPEB4,GNPDA1,ST14,CTSB,HEXB,ASAH1,IL18,F11R,FAM21C,GNS,ZFYVE16,SESN3,ALG13,TMEM62,MGAT4A,AIM1,PAPSS1,SORL1,ZNF230,RCAN3,NFKB2,IL10RB,GM2A,MYO5A,TRAK2,GCNT1,PARP9,P2RX4,QSOX1,TIMP2,ALDH2,PLSCR1,ITCH,SAT1,TMEM144,KIAA1109,PRKAR2B,SLC17A5,LHFPL2,MYOM1,BBS2,ALCAM,ATP10D,TXK,SCARB2,ZNF641,RCBTB2,PRCP,CTNND1,SAMD8,PLD1,TMEM159,LTA4H,IFIH1,SAT2,ARNT,RRAGD,TMEM131 |
| 3.474e-02 | -3.36 | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN | 171 | 34 | 17758 | 2588 |
CTHRC1,DYRK3,UGP2,GRHL2,IL15,SEC61G,EGR3,SLC1A3,MORF4L2,MNS1,NRP2,PLS3,CAPN2,BTG3,SELK,HSPA13,TMED2,LAMP3,PRSS23,STAT4,LYRM1,AK4,RAB3IP,CD40,FNDC3A,ARF4,UAP1,RAP2C,MYLK,RAB11FIP1,ALG2,SERPINB1,ABCG1,ESYT2 |
| 3.480e-02 | -3.36 | AACATTC,MIR-409-3P | MSigDB lists | AACATTC,MIR-409-3P | 136 | 28 | 17758 | 2588 |
CDK17,KCNIP3,MMD,AMFR,OSGIN2,KCTD12,TGFBR1,GRK6,NDRG3,FZD7,CDK14,PTPRF,PDCD10,TGFBR3,FICD,CSNK1G1,FRAS1,FOSB,MYLK,UBE2J1,TWIST1,NR4A2,CTNND1,HS3ST3B1,ZBTB6,MAL2,SLC39A10,CITED2 |
| 3.480e-02 | -3.36 | developmental growth involved in morphogenesis | biological process | GO:0060560 | 116 | 25 | 16441 | 2455 |
EPB41L5,EMX1,FMN1,TMTC3,IQGAP1,SOX9,TFAP2C,ALCAM,ULK2,NRP2,MAP1B,AREG,FGFR2,PTK7,CSF1,FLRT3,SLC9A6,AURKA,EFNA5,WNT3A,SEMA3A,SLC12A2,SPRY2,COBL,RARG |
| 3.488e-02 | -3.36 | apical plasma membrane | cellular component | GO:0016324 | 277 | 52 | 17570 | 2579 |
CTSB,PRKAA1,FLOT1,ERBB2,SYTL4,EMP2,ANO1,SLC9A3R2,FZD6,EPCAM,SCNN1A,PTEN,KCNN4,SLC46A1,CD9,PRKCI,CLDN4,ATP8B1,IGFBP2,ERBB3,PDE4D,RAB27B,SLC12A2,FLOT2,MYRIP,AMOTL2,ADAM17,CRB3,RAPGEF2,VAMP3,MGAM,EZR,SLC11A2,ATP1B1,STX3,DUOX1,PROM1,ATP1A1,TJP3,KCNK1,SHROOM3,STK26,TMEM30A,OSMR,STK39,NRG1,MAL2,PLD1,SHROOM2,LZTS1,OCLN,PROM2 |
| 3.492e-02 | -3.35 | positive regulation of homotypic cell-cell adhesion | biological process | GO:0034112 | 196 | 39 | 16441 | 2455 |
DHPS,IL15,HLA-E,TRAF2,GATA3,IL18,EGR3,CD274,TNFSF9,EFNB1,HLA-A,CD46,IL6ST,PAK2,PIK3CA,IGFBP2,MAP3K7,RAG1,FLOT2,SYK,RASGRP1,SOCS5,HES1,CD55,RHOA,AKT1,RIPK2,LGALS8,DMTN,PIK3R1,PRKCQ,YES1,CD83,BCL10,FYN,NR4A3,NOD2,ICOSLG,JAK3 |
| 3.494e-02 | -3.35 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN | 458 | 81 | 17758 | 2588 |
SUN1,ACACB,NQO1,THRA,RET,IL27RA,MXD1,WEE1,KCTD15,RPS6KA2,SIVA1,SRR,KIF22,EPHB4,PHKA2,ARL4D,TRAM1,IL10RB,SCYL3,NR2C1,NAGA,ENPP4,PLK1,ORAI2,PSRC1,CELSR2,LGALS8,SEPT6,ARFRP1,AURKB,CASP4,TRIOBP,MAOA,EFNA5,TMEM8B,PDXK,UNC5B,ARNT,ANXA3,NUDT6,RECQL,CDKN1C,PPP1R12A,CTSB,ZCCHC24,OSGIN2,NOTCH2,IFT27,PSIP1,CALR,FLII,ANK1,BMP7,RRBP1,BAX,ATP8B1,H2AFY,OSTF1,MYLIP,EEF1D,MED22,PAPD7,RAPGEF2,RC3H2,DBR1,DIAPH2,FBXO9,CYFIP2,NDRG3,GNA11,MFSD7,RHOB,RASGRP2,ENDOD1,DCAF10,MAPKAPK2,BTG1,DTX4,ERAP1,NDE1,AHR |
| 3.496e-02 | -3.35 | HEIDENBLAD_AMPLICON_12P11_12_UP | MSigDB lists | HEIDENBLAD_AMPLICON_12P11_12_UP | 32 | 9 | 17758 | 2588 |
RASSF8,CTSC,KCNK5,SPA17,KIF1C,GEM,NTAN1,RPGR,FGFR1OP2 |
| 3.496e-02 | -3.35 | GHANDHI_DIRECT_IRRADIATION_DN | MSigDB lists | GHANDHI_DIRECT_IRRADIATION_DN | 32 | 9 | 17758 | 2588 |
PLEKHA6,FZD4,ARHGEF37,PTK7,SYBU,NR3C2,RGMA,MDFI,IRF1 |
| 3.497e-02 | -3.35 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 1157 | 190 | 17775 | 2585 |
LTBP1,HECA,PPP4R4,FAM160B1,TTC39B,DNAJC3,CUL1,CA8,CARD10,TMC1,SLC9A7,SH3KBP1,ZFYVE16,CTNNB1,ANKFN1,ABCA2,POF1B,ATRNL1,MARCH2,ANO4,TLN2,TRAM1,ZNF462,SPATA18,SNTB2,ITCH,DSTN,CDYL,PPP1R14C,MYOM1,ADRBK2,ABR,OPTN,CXXC4,TRIM9,ZNF114,ARHGEF19,TDRD7,FAM110C,ZNF165,HDAC1,PIEZO1,LEMD1,UNC5B,APBA2,PDPR,CPPED1,DLAT,CDK17,FRMD4A,MTL5,CNTNAP2,PM20D2,NOTCH2,DOCK11,APBA1,TNFRSF19,DHRS3,FBLN1,UBE2Q2,IGF1R,FAM189A1,FRAS1,AIM1,COL6A1,MSH2,FBXL14,PRKG1,MAP3K9,FAR2,MOXD1,TMEM8A,DGKG,SYTL3,ZNF117,SNED1,WDR72,CEP89,SALL4,MICB,LPGAT1,RANBP9,CYB5A,FAS,NT5C2,INSR,HTT,SLC4A3,KLK7,KIF12,PER3,SEMA3A,CBX5,AFAP1,DOCK9,LMO7,ARHGAP11A,NCKAP5,TPRN,MTM1,TCF25,TCTN2,DLGAP5,CCDC110,WDTC1,TP53,MRAS,FLT3,APC2,SYTL2,APPBP2,TTC21B,SS18,MUC16,TACC2,WDR44,ZDHHC12,BCL6,RTKN2,ECE1,ETHE1,MYT1,SULF2,MYO5B,DOCK4,SNX8,CAMSAP3,AGPS,UTRN,CBL,TMTC2,ALCAM,ARHGAP35,PEX5,CDK19,PLEKHG1,TLE1,MAOA,RCAN2,C1orf43,SLC25A30,COBL,FAM134B,TRAPPC10,ARHGEF7,CCNJL,SELL,PBX3,SLC25A43,ETS1,LGALS3BP,C16orf74,MLPH,PTEN,GPC3,GTF2F2,HSPA13,SGCB,MYO5A,DLGAP1,NFE2L3,CASK,RAPGEF2,TCFL5,PIK3R1,MBNL3,DIAPH2,RAB3IP,BLVRA,LRRC1,FAM73B,GRTP1,CRISPLD2,FUCA1,RGS9,BANK1,PROM1,SWAP70,FAT4,SLC35B3,FIBCD1,PLA2G15,UBE2D2,PPM1H,ARSB,L1CAM,DCBLD1,ZBTB33,CD33,GOLGB1 |
| 3.502e-02 | -3.35 | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 177 | 35 | 17758 | 2588 |
PNISR,ST13,ZNF395,CD63,GNPDA1,CAST,LRP4,HEXB,ASAH1,HDAC6,NTAN1,CCDC64B,PHF1,M6PR,GNS,RPS6KA2,CKS1B,BRI3,NPTN,DVL2,ATP2B1,LAMP2,OPLAH,PPARA,TMEM144,NPC2,FNDC3A,RHEB,GLCE,LRRC42,AP1AR,UBE2D2,PIK3C2B,PHC1,RRAGD |
| 3.505e-02 | -3.35 | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | MSigDB lists | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | 37 | 10 | 17758 | 2588 |
CCND1,TNRC6C,LFNG,FURIN,E2F1,TP53,RAB6A,NOTCH3,NOTCH2,TMED2 |
| 3.505e-02 | -3.35 | ZHAN_MULTIPLE_MYELOMA_LB_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_LB_DN | 37 | 10 | 17758 | 2588 |
TACC1,USP18,STAT1,AKNA,ZMIZ1,TRAF5,CASP4,IFI6,SEPHS1,IRF1 |
| 3.505e-02 | -3.35 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP | 37 | 10 | 17758 | 2588 |
APLP2,GCLM,CLCN3,AGRN,S100A11,FHL2,GTF3A,ACADM,C15orf39,PLS3 |
| 3.505e-02 | -3.35 | GEISS_RESPONSE_TO_DSRNA_UP | MSigDB lists | GEISS_RESPONSE_TO_DSRNA_UP | 37 | 10 | 17758 | 2588 |
IGFBP6,PLAUR,NFKBIA,NMI,SAT1,TAP1,IFIT1,AFAP1,ELF3,IRF1 |
| 3.505e-02 | -3.35 | SULFUR_METABOLIC_PROCESS | MSigDB lists | SULFUR_METABOLIC_PROCESS | 37 | 10 | 17758 | 2588 |
GCLM,HS6ST1,SOD1,CTNS,GCLC,CSGALNACT1,TPST1,HS3ST3B1,CHST2,GLCE |
| 3.505e-02 | -3.35 | GNF2_CD97 | MSigDB lists | GNF2_CD97 | 37 | 10 | 17758 | 2588 |
JAK1,IQGAP1,HLA-E,HLA-F,STK38,RIN3,LITAF,PTGER4,EFHD2,OSTF1 |
| 3.505e-02 | -3.35 | VARELA_ZMPSTE24_TARGETS_UP | MSigDB lists | VARELA_ZMPSTE24_TARGETS_UP | 37 | 10 | 17758 | 2588 |
MAPKAPK2,KLF3,PIM3,BCL2L1,C15orf39,SLC20A1,SESN1,LEPR,TIPRL,CYP26A1 |
| 3.505e-02 | -3.35 | BROWNE_HCMV_INFECTION_2HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_2HR_UP | 37 | 10 | 17758 | 2588 |
NR4A1,NFKBIA,NR4A3,ERP44,NR4A2,FOS,DHRS3,SNED1,ICAM1,IRF1 |
| 3.505e-02 | -3.35 | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | MSigDB lists | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | 37 | 10 | 17758 | 2588 |
CALM2,RASGRF1,RPS6KA2,CAMKK1,RPS6KA1,CALM1,GRIN1,CALM3,GRIN2D,RPS6KA3 |
| 3.510e-02 | -3.35 | SEIDEN_ONCOGENESIS_BY_MET | MSigDB lists | SEIDEN_ONCOGENESIS_BY_MET | 85 | 19 | 17758 | 2588 |
ANXA3,SEC23A,SLC25A24,SH3BGRL,ITGA6,EPS8,MMADHC,NCKAP1,CDK1,PLS3,CD46,PLOD2,PTEN,HNRNPH2,STAT1,PPP1CB,TRAM1,F2RL1,TMX1 |
| 3.510e-02 | -3.35 | VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | MSigDB lists | VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | 85 | 19 | 17758 | 2588 |
PRSS8,GALK1,CAMSAP3,AASS,ETV5,BNIP3L,EZR,PKP2,CTSZ,SYDE2,IER3,AP1M2,ITGA3,CDH1,PFKL,ALPK3,TAGLN2,EGLN3,CBX7 |
| 3.512e-02 | -3.35 | RHO | smart domains | SM00174 | 25 | 8 | 9131 | 1455 |
RAC2,RHOA,RND3,RAP2C,RHOBTB2,RHOB,RHEB,RND1 |
| 3.520e-02 | -3.35 | hydrolase activity, hydrolyzing N-glycosyl compounds | molecular function | GO:0016799 | 22 | 7 | 16491 | 2452 |
MAN2A2,ADPRHL1,NEIL1,PCNA,ART5,NEIL3,CCNO |
| 3.520e-02 | -3.35 | Irinotecan Action Pathway | SMPDB pathways | SMP00433 | 21 | 8 | 978 | 190 |
CES2,ABCB1,ABCG2,DNAJB11,ERP29,PDIA6,PDIA4,ABCC1 |
| 3.520e-02 | -3.35 | Irinotecan Metabolism Pathway | SMPDB pathways | SMP00600 | 21 | 8 | 978 | 190 |
CES2,ABCB1,ABCG2,DNAJB11,ERP29,PDIA6,PDIA4,ABCC1 |
| 3.525e-02 | -3.35 | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN | 183 | 36 | 17758 | 2588 |
ST13,UGP2,TBC1D1,DAP,RALBP1,FAM134A,ARFGEF1,C6orf106,NENF,HDAC6,GSTP1,PSIP1,CORO1B,SNTA1,WEE1,C7orf49,PLK4,UBE2J1,TIAM1,ABCC1,SYPL1,PTPN18,ALDH2,MRPS33,SYBU,C1GALT1C1,ERP44,PDHX,STK17A,SGPP1,FAS,AMZ2,NEIL1,CDK19,RAD21,DLAT |
| 3.527e-02 | -3.34 | positive regulation of canonical Wnt signaling pathway | biological process | GO:0090263 | 133 | 28 | 16441 | 2455 |
LGR4,PSMB4,WNT10B,ASPM,PSME2,AMER1,PSMD7,XIAP,PSMD10,PSME1,ILK,PSMA4,PPP2R3A,PSMD1,RNF220,GPRC5B,CTNNB1,FGFR2,PSMD3,PSMC2,DIXDC1,LRRK1,WNT3A,FZD5,PSMC1,DVL2,PSMA5,RNF146 |
| 3.530e-02 | -3.34 | PDGF_2 | prosite domains | PS50278 | 9 | 4 | 11866 | 1802 |
PDGFA,PGF,PDGFC,PDGFB |
| 3.534e-02 | -3.34 | striated_muscle | COSMIC cancer mutations | striated_muscle | 4392 | 676 | 17775 | 2585 |
DOC2A,HECA,ACACB,ADD1,IBTK,GRIK2,TRIM5,DNAJC3,HEXB,RET,FBXO2,NRG2,BAIAP3,KIF26A,PHF1,LTBP3,EPDR1,CDKN2C,TP73,NPM2,ZYX,TGFBR3,DNAH6,CABP1,PAQR5,RDH14,ALDH1A3,KLF3,CRY2,IL10RB,ODF2L,APOBEC3G,ERAP2,DNAAF3,NEK4,NWD1,SPEF2,SMARCA2,TNIP1,CDA,LOXL2,MYOM1,PNKD,COL12A1,LCP1,PIAS3,ENPP1,GRID2IP,DNM1L,ANKRD6,MYLK,FAM114A1,NOD2,STARD13,PDPR,ZNF720,SCN5A,CYP2J2,ITGA6,RAB23,ZNRF3,CCDC64B,MERTK,LMNA,MARCH8,FAM189A1,CD22,MEGF8,FLRT3,ZIC5,FBXO7,CADPS2,USP1,ALPK1,CNGA1,ZMYM1,MOXD1,PPP6R1,SLC37A1,MYBL2,KIF20B,GNA11,IL1R1,NCOA3,ETS2,HTT,SEMA4D,ITPR1,OSMR,DYSF,DRP2,TMEM173,XDH,ADAMTS16,DOCK9,MTM1,PAPSS2,LFNG,GALNT12,FAM131C,PTTG1,WDTC1,RGS20,PKP2,TESK2,KIAA1147,UHRF1BP1L,MUC16,CDH1,SH3BP1,RTKN2,MYT1,SCN3A,TMCC2,MX1,CAMSAP3,COL6A2,ERMP1,RIPK2,SYNE2,GIGYF1,NFIX,CCNB3,WFS1,CORO1C,SLC9A6,PLEKHG1,FAM149A,DMWD,CTHRC1,PARP14,ESRP1,RASSF7,NUCB2,PLPPR4,GSTP1,ETS1,BEX2,ICAM1,NEO1,CXCL16,ANK1,ADD3,IRAK1,ARSG,GPC3,TUBGCP6,FDXR,TMBIM6,IGFBP2,NPTXR,RAG1,TPCN1,PARP9,AMOTL2,FMN1,MFSD2B,PIK3R1,PLEKHA7,MYEOV,PGBD1,EMP3,PROM1,PLOD2,ATXN7L3,CCDC6,RAB11FIP2,ACVRL1,ZFP30,FAM3C,DBI,PPM1H,FBXO44,CENPE,FHL1,FOXA1,PHC1,TMEM131,BCAM,KIAA1462,AGRN,FHDC1,NENF,GALM,SPTB,TFAP2E,SUSD2,ENTPD4,NUP210,TM9SF2,CTNNB1,P4HB,PSMC2,TMEM143,ABCA2,ANO4,TLN2,NEB,CCDC38,ZNF462,THRB,MCTP1,MARK1,PTPN18,CD55,EZR,CCBL2,CR2,IDH1,OPTN,KDM4D,IRX3,TNS4,HS6ST1,PLCH1,MAP2,P4HA2,ZNF367,RAB11FIP1,ARRDC1,KLF11,PIK3C2B,PIEZO1,TTC39C,EPB41L4A,TC2N,PRSS8,USH1C,LGALS3,RASA2,PDCL,HES2,CNTNAP2,DOCK11,FBLN1,RSAD1,ANO1,SSX2IP,RB1,KIAA0895,UBE2Q2,IGF1R,FRAS1,TBCD,SLC30A6,PLCB2,DPYSL5,USP31,SPATA13,TCF7,RASGRP2,DHDH,FA2H,H1F0,COL13A1,ITGA7,NLRC5,LTBP2,PLD1,ZDBF2,CTBP1,RAD21,USP43,NF2,UPF3B,TP53,ERBB2,P2RX7,SLC7A2,C1orf116,CYP26A1,SYTL2,IER3,PDGFA,SRPX,WDR44,TACC2,PLCG2,BCL6,GYS1,ESPN,NOTCH3,OAS3,MINPP1,SCN2A,PPIF,AKT1,ACO1,PTGER4,ATP13A2,MYPOP,DUOX1,ZNF628,PTPRJ,ABHD12,PTK7,STK38,ADAMTS14,MAOA,IRF7,ANXA9,ST3GAL1,ZC3HC1,COL9A3,DYRK3,TM2D2,CDH22,TRAPPC10,KLHL13,MACC1,RUSC2,CTSB,GDF15,JAG2,CRABP2,DSE,LBR,SH2D4A,FZD6,CD109,TFAP2A,FAM63A,TSPAN13,BUB1,CAMK2G,GCNT1,LRRC24,IGDCC4,NFE2L3,P2RX4,HMMR,MOSPD2,PLAUR,LITAF,PPARA,PRICKLE1,DPP9,MAML2,COL7A1,CAPNS1,NPDC1,RNPEP,BBS2,TXNDC11,BCAR1,CNOT2,SERPINA1,FAT4,TWSG1,ZMYND19,NAT1,NETO2,E2F1,PPP2R3C,ICOSLG,TBC1D4,PTGES,ARHGEF4,GOLGB1,GAA,HSPG2,SSH1,TAP1,VASH1,FAM101B,PICK1,CYP1A1,OSBPL3,RGS3,PIK3CA,KCNS3,POLL,AOX1,ATRNL1,HYLS1,MTMR11,RCAN3,SPATA18,ACVR1C,CASP9,KIF13A,CCNF,ULK2,PLK2,GNPTAB,DHTKD1,MAPK13,TANC2,LZTS1,FGD1,DDX58,INPPL1,FRMD4A,DHPS,TBC1D1,DGKQ,KIF23,NOTCH2,SLC1A3,PDXDC1,KIAA1161,DOPEY2,CYR61,ZNRF2,NECAB3,AIM1,MSH2,OPN3,SORL1,PIKFYVE,CTSD,EEF1D,RIMS2,SOCS5,IGSF3,DNAI1,GFPT1,SPATA20,KCNJ12,PRSS23,MFI2,ADCK3,MICB,AMER1,DCHS1,WHSC1,PYGL,ATP8B3,ANTXR1,FRMD4B,FAS,DGKH,AP1AR,TJP3,FAM64A,DCK,AGBL5,FAM83D,CABIN1,PER3,PLIN3,MAP3K5,IFIH1,EHD1,PKD1L2,PLA2G4A,PLEKHG3,SPRED1,CAPN12,NLRX1,DDIT4L,IRX4,KCTD12,FLT3,CYP39A1,EPM2A,EPS8L2,APLP2,FAM46A,FICD,PHKA2,LGMN,NR2C1,NAGA,TBC1D10B,ATG4D,DOCK4,SEC23A,FOXJ2,TEP1,PRKCQ,PYGO1,ITPR3,ALCAM,ATP10D,ZNF469,NIN,EPHA10,ACAD10,HAGHL,KIAA1804,TRIOBP,FAM195A,SLC27A1,NRG1,KLF5,MLKL,COBL,ANKRD13D,PCOLCE,CENPI,PBX3,CYB561,PLD2,APOBEC3H,DNAH3,MGAT1,PTEN,FJX1,ERBB3,MAP3K7,GFI1,MSH6,TGIF1,SHMT1,ARAP2,PAPD7,TCFL5,FURIN,DIAPH2,LRRC1,GRTP1,RGS9,MAMDC4,FGFR2,RIN3,ABCB1,ERAP1,RABL6,FZD5,NCAPG2,OCLN,DEF6,USP16,JARID2,RGMA,LTBP1,NMRK1,TMEM184B,CPT2,CAMKK1,EPHX4,DNER,TMC1,PTCHD4,SH3KBP1,ARHGEF10L,SIPA1L2,LRRC6,ARHGEF37,TSPAN6,ANKFN1,PHTF1,CAPG,DLG1,MYH14,SLC39A10,TECR,IL1RAP,CYP1B1,LAP3,RNF165,RGAG1,TCN2,NEIL1,HPSE,MADD,RBM43,APBA2,RAP1GAP,CAPN1,GRN,FAM213B,ARAP3,PEX6,PYROXD2,ASL,ABCG2,PHLPP1,ADAMTSL4,TYW3,FAM20C,KCNN4,COL6A1,EBF4,FNIP1,SRP54,FXYD5,NPTN,ZRANB1,CCDC88A,SNED1,PODXL2,PARD3B,GYLTL1B,BTN3A2,VWA1,KIAA1109,RANBP9,EGFR,MUM1L1,GNAS,FECH,TSC1,CGREF1,RHOBTB2,YOD1,DONSON,SHROOM2,JAK3,FBXW5,CCNE2,NCKAP5,ZSWIM5,SORBS1,MORC4,COL18A1,ARHGEF16,SS18,ZNF687,ARTN,SMO,STEAP3,ECE1,NFKB2,ETHE1,LOXL1,SLC39A8,OSTM1,DUSP4,DOCK5,ARHGAP35,ALDH5A1,BFSP1,SPTBN5,PLXND1,AKNA,REEP4,ABCA1,CBX4,GLIS3,ARHGEF11,ARHGEF7,LRP4,COL4A5,NOTUM,SBF1,ITGA2B,TMEM63A,HDAC9,KIF5B,IL17RB,IRF2BPL,SNX13,CARD8,ADORA1,MLPH,LLGL2,TOX2,KIAA0319,BRD7,IQGAP3,C12orf75,RPGR,MYO5A,SUN2,DCAF6,WNT10B,ASPM,PHLDB3,NR4A1,SYBU,LRRC66,OGDHL,TTC7A,POLD3,LEPR,MPV17L2,SPAG1,HLA-B,CASP7,SOX8,PLOD3,AHR,NGEF,ZNF596 |
| 3.544e-02 | -3.34 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN | 189 | 37 | 17758 | 2588 |
UGT8,RUNX2,TTC39B,NFKBIE,FOXM1,LFNG,ARMC7,FAM78A,SPSB1,TMCC3,DAPK2,WEE1,CDH1,CTSC,IQCE,CAPG,ZDHHC23,RAB20,RCAN3,CYP1B1,SUSD3,CPD,LRRC66,LITAF,DIAPH2,EGFR,NMT2,GABARAPL1,RASGRP2,CD8A,ISM1,C1orf21,FAM3C,NR4A3,F2RL1,AHR,FGD1 |
| 3.544e-02 | -3.34 | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP | 189 | 37 | 17758 | 2588 |
ARHGEF3,IL15RA,SERPINB9,XIAP,PDIA5,SELL,CD274,PHLDA1,DUSP5,PSIP1,ZDHHC21,DOPEY2,SPIN4,WDR44,TMEM62,PSMC2,TSPAN13,RFX5,ACAD8,CNOT6L,C12orf75,PIGC,PCGF5,ZC3H11A,IFITM3,DENND1B,DBR1,BORA,SERTAD2,FYN,DNM1L,ANKRD6,ITPR1,PRPS2,PGM2L1,CENPE,ESYT2 |
| 3.544e-02 | -3.34 | GSE3982_EOSINOPHIL_VS_BASOPHIL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_BASOPHIL_UP | 189 | 37 | 17758 | 2588 |
GAA,UGT8,TCF25,LGR4,PLEKHJ1,WDTC1,ASAH1,SNN,NTAN1,ARHGEF40,EXT2,SYTL2,SIRPA,PER2,NOV,ZNF75D,VASP,MCF2L,FAM13B,TIPARP,MYO5A,GCNT1,DOCK4,MBP,CTNNAL1,KLK6,PCTP,ALCAM,GALNT3,PLEKHG6,AGPAT2,P4HA2,PPP1CB,PRKCDBP,TMEM8B,SPRY4,RGS14 |
| 3.544e-02 | -3.34 | GSE3982_MAC_VS_TH2_DN | MSigDB lists | GSE3982_MAC_VS_TH2_DN | 189 | 37 | 17758 | 2588 |
FAF2,DGKA,FLOT1,KIF23,HOXB2,REPS1,CYP1A1,CCNA2,DLG1,ZDHHC13,TMEM143,PRC1,CKS1B,ZNF692,MAPK11,ERCC2,APOBEC3G,HMMR,TDP1,SHMT1,SEPT6,SYNE2,EZR,GTF2A2,CYFIP2,CDC25C,GINS4,GALNT3,GABRD,SLC25A4,XRCC3,NUP37,EPB41L4A,C17orf75,ZBTB33,DEF6,CAPN1 |
| 3.544e-02 | -3.34 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN | 189 | 37 | 17758 | 2588 |
PCOLCE,AGRN,GRHL2,FXYD3,MTL5,ABCG4,COL18A1,PLXNA1,TRIB2,RSAD1,SIRPA,CAPN2,FRY,LLGL2,STIM1,PASK,FAM63A,SORL1,ADAM15,FAM102A,MAST4,ALDH3A2,CTDSP2,S100A6,CKAP4,EBAG9,MARK1,PLEKHB1,BCL10,TXK,RBM47,DGCR2,ACADSB,CABIN1,MAPK13,MYL12B,AFAP1 |
| 3.544e-02 | -3.34 | GSE3982_MAC_VS_TH1_DN | MSigDB lists | GSE3982_MAC_VS_TH1_DN | 189 | 37 | 17758 | 2588 |
PPP1R2,DGKA,FLOT1,KIF23,PDGFA,BTG3,HSF2,DNAH6,PRC1,ZDHHC13,SRP54,KNTC1,ERCC2,HSPA2,ERAP2,HMMR,TAF5,EZR,NUSAP1,EIF2AK1,PDK3,PKMYT1,POLD3,GINS4,SFXN1,CDCA4,PAFAH1B3,KCNK1,PRDX3,SH2D3C,CSNK1G1,DMWD,NCAPG2,F2RL1,SERPINB1,TRAF5,DEF6 |
| 3.544e-02 | -3.34 | GSE17721_4_VS_24H_GARDIQUIMOD_BMDM_UP | MSigDB lists | GSE17721_4_VS_24H_GARDIQUIMOD_BMDM_UP | 189 | 37 | 17758 | 2588 |
ANXA3,ARMCX3,TSPAN15,ARHGEF7,ABCG4,ABCG2,HMGN3,PSME1,SNN,PLA2G16,OXCT1,KCNN4,IL6ST,ELF5,FXYD5,PLEKHF1,ECE1,PDIA6,TRAM1,KANK3,S100A13,EEF1D,GM2A,MYO5A,UXT,ITCH,KIF1C,GALNT3,RND3,HS3ST3B1,ARF6,SERPINB1,UBE2C,RARG,MAFF,ANXA11,MELK |
| 3.545e-02 | -3.34 | sensory organ morphogenesis | biological process | GO:0090596 | 249 | 48 | 16441 | 2455 |
CTHRC1,PAX6,USH1C,SOX9,GATA3,OSR2,SIX4,PPP2R3A,FZD6,GBX2,CTNNB1,GATA2,BMP7,ALDH1A3,FJX1,PRKCI,BAX,TFAP2A,TWIST1,WNT3A,NTN1,GFI1,SPRY2,RPGR,DVL2,SOD1,SCRIB,PRKRA,ABR,BCAR3,PITX2,PROM1,FGFR2,TBX1,PTK7,NKD1,LRIG1,TBX18,NR4A3,TDRD7,HDAC1,GDF11,SOX8,OSR1,FZD5,SHROOM2,RARG,HOXC13 |
| 3.546e-02 | -3.34 | human chr4p14 | chromosome location | human chr4p14 | 30 | 7 | 26250 | 2805 |
ARAP2,RELL1,RBM47,TBC1D1,WDR19,FAM114A1,KLF3 |
| 3.548e-02 | -3.34 | PI Metabolism | REACTOME pathways | R-HSA-1483255 | 51 | 13 | 8202 | 1235 |
MTM1,PI4K2B,INPP5E,INPPL1,PTEN,INPP5D,OCRL,PIK3R1,INPP4B,PIK3CA,PIK3C2B,PIK3CD,PIKFYVE |
| 3.548e-02 | -3.34 | Phospholipase C-mediated cascade; FGFR2 | REACTOME pathways | R-HSA-5654221 | 51 | 13 | 8202 | 1235 |
CALM2,PLCG1,ADRBK1,FGFR2,CALM1,FGF18,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PRKAR1A |
| 3.550e-02 | -3.34 | Toll Like Receptor 4 (TLR4) Cascade | REACTOME pathways | R-HSA-166016 | 121 | 26 | 8202 | 1235 |
SIGIRR,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,PLCG2,UBE2D2,DNM2,NOD2,IRF7,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 3.555e-02 | -3.34 | V$AP1_Q2 | MSigDB lists | V$AP1_Q2 | 255 | 48 | 17758 | 2588 |
CMAS,TXN,FARP1,IGFBP6,SCOC,CAMKK1,ETV5,CALM3,PLAC1,PRKACA,SLC35E4,LTBP3,SIX4,ZNF385B,LMNA,PAK6,CALM2,RNF128,FAM46A,IRAK1,SHC3,KCNN4,NECAB3,SLC16A6,CDKN1B,MDFI,TBC1D10B,SMARCA2,ELK3,TRIM8,CASK,DSTN,CALM1,DCHS1,PTPRH,CAPNS1,FOS,KDM3A,TBC1D17,MPRIP,MAP2,CORO1C,S100A5,EFNA1,C1orf43,UBE2C,TOB1,RTN3 |
| 3.559e-02 | -3.34 | GSE17721_0.5H_VS_8H_POLYIC_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_8H_POLYIC_BMDM_DN | 195 | 38 | 17758 | 2588 |
MAN1A2,ABCG2,EFHD2,NDRG2,SH3KBP1,SLC25A45,PCNA,ADORA1,CTSC,CDK16,LMO4,SNX16,CD70,MDFIC,CACNA1D,PTPRE,GCA,LAP3,NR3C1,IGSF8,RNPEP,SPTLC2,ARF4,EDNRA,ENDOD1,PTPRJ,RND3,CCDC6,STK38,ZDHHC20,ITPR1,PIAS2,HDAC1,PPP1CB,HMGA1,CENPE,RBM43,MAP3K5 |
| 3.559e-02 | -3.34 | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 195 | 38 | 17758 | 2588 |
LASP1,CAMKK1,NCKAP1,SH3KBP1,PER2,ATP6V0B,SCNN1A,IGF1R,ARSG,GATA2,FAM13B,COL6A1,ATP8B1,EPHB4,RASGEF1A,LRP11,EGLN3,F2R,CASD1,CPD,MMD,CTNNAL1,FHL2,CLSTN1,PYGL,CALCRL,PRKCQ,LDB2,BSDC1,TCN2,BTG1,BANK1,MYLK,SPINT2,PLD1,ARHGAP4,LTA4H,EHD1 |
| 3.559e-02 | -3.34 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | 195 | 38 | 17758 | 2588 |
RECQL,TAOK2,TRIM24,ITGA6,P2RX7,NKRF,TGFBR1,FAM78A,TMEM170B,DOCK11,RSAD1,KCTD9,SETDB2,FAM160A2,RINL,SLC16A6,OSBPL3,RUNDC3B,PTPRE,GFI1,PPP6R1,CYP1B1,GCC2,LOC81691,LGALS8,PDE5A,TTC7A,ZSCAN12,PDE11A,XKRX,CRTC2,AHRR,ZDHHC20,NR4A3,ERAP1,PER3,GLCCI1,CBX7 |
| 3.559e-02 | -3.34 | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN | 195 | 38 | 17758 | 2588 |
PRSS8,KIF3C,SEC61G,DNAJC3,TAP1,PDIA5,PLXNA1,CRABP2,NUCB2,ERP29,EXT2,SLC35E4,LMNA,CORO1B,NOV,NPNT,CST3,H2AFY,ECE1,ITM2C,SEPT6,NFE2L1,CAPNS1,ERP44,NPC2,ESYT1,CDK1,VCP,FUCA1,TAPBP,SLC6A6,MID1IP1,MPRIP,PEX5,PAFAH1B3,TWSG1,IRF7,CD81 |
| 3.559e-02 | -3.34 | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP | 195 | 38 | 17758 | 2588 |
CASP3,PARP12,PDIA5,SELL,HMGN3,EGR3,PLXNA1,DOCK11,PHLDA1,SNX9,DENND2D,DUSP5,FAM111A,FAM46A,SPIN4,BAX,CNOT6L,PTPRE,C12orf75,SLC35A1,NCOA2,CTH,SEPHS1,PIGC,BAG4,ARAP2,CORO2A,MBNL3,PTGER4,DBR1,KIF20B,SLCO4A1,FYN,PTER,MRPS28,PLXND1,CD81,CBX4 |
| 3.559e-02 | -3.34 | GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN | MSigDB lists | GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN | 195 | 38 | 17758 | 2588 |
TUBB4B,MRPS15,APOO,BCL2L1,HMGXB4,PCNA,RANBP1,PRC1,CKS1B,TUBG1,TNFRSF12A,USP1,MANF,MSH6,SMC4,CKS2,CPD,MLEC,HN1L,MMD,CTNNAL1,SLC39A8,PBK,CDC20,MRPS35,FANCE,STX3,ZMPSTE24,SFXN1,SLCO4A1,ATP1A1,PRDX3,CORO1C,PGRMC1,DONSON,KPNA2,NUP37,USP16 |
| 3.562e-02 | -3.33 | YEGNASUBRAMANIAN_PROSTATE_CANCER | MSigDB lists | YEGNASUBRAMANIAN_PROSTATE_CANCER | 119 | 25 | 17758 | 2588 |
NKX3-1,ALDH6A1,HMGN5,SLC39A8,ADO,NDC80,KIF23,CENPN,TRIM68,ARHGEF26,FECH,SERPINA1,DHRS2,ELF5,GTF2F2,CLDN4,DONSON,HOXB13,ERBB3,MYBL1,ALDH3A2,OCLN,MCCC2,GCNT1,CTH |
| 3.565e-02 | -3.33 | V$OCT1_01 | MSigDB lists | V$OCT1_01 | 249 | 47 | 17758 | 2588 |
PAX6,THRA,HPCAL4,SLC25A35,PPP2R3A,HDAC9,CCND1,ZFX,SESN3,IRAK1,PTEN,CYR61,LLGL2,LMO4,LHX6,MITF,PRKG1,TSPAN13,PDE4D,EGLN3,CITED2,DGKG,CPD,ING1,PCDH1,PLEKHA6,ASXL1,FZD4,SH3BGRL,SERTAD4,KIF13A,PYGO1,ITPR3,TP53INP2,RHOB,NIN,NFIX,CXXC4,TSC1,KLF12,NEIL3,RHOBTB2,FAM117A,SP6,CEP41,JARID2,NXT2 |
| 3.565e-02 | -3.33 | V$AP4_01 | MSigDB lists | V$AP4_01 | 249 | 47 | 17758 | 2588 |
DOC2A,IER5L,LTBP1,KIF3C,TNRC6C,SORBS1,PPM1J,ATP8A1,CTDSPL,ADO,MCTP2,PDIA3,NDUFA4,PJA2,TFAP4,ADRBK1,LLGL2,CDK16,SH3BP1,CASC4,TMEM62,KCNK5,HEXIM2,RASGEF1A,SULT2B1,DNAI1,MAP3K3,PCDH1,PLEKHA6,ACVR1C,RGAG1,PRICKLE1,TCF7,SRRM3,NFIB,MAPK8IP1,PITX2,BOLA3,H1F0,PSMD3,RAP2C,NAB2,GRIN2D,NR4A2,SPRY4,MAP3K5,RUSC1 |
| 3.574e-02 | -3.33 | V$PXR_Q2 | MSigDB lists | V$PXR_Q2 | 243 | 46 | 17758 | 2588 |
UGP2,HEBP1,ADO,XYLT1,ETV5,NDRG2,PSME1,MICALL2,DHRS3,PRKACA,SYTL2,ZDHHC21,SCNN1A,CTGF,ZCCHC12,CABP1,LMO4,VASN,PLCG2,FABP6,MITF,CKS1B,ATRNL1,ADAM15,MANF,ETV4,CCDC88A,HES1,BCL9,SAT1,PYGL,TNS1,AKAP3,ATP1B1,PITX2,SLC6A6,MPP2,NR4A3,OVOL1,ZDHHC7,NRG1,NR3C2,RARG,HOXC13,KLF7,NR2C2 |
| 3.574e-02 | -3.33 | V$RFX1_01 | MSigDB lists | V$RFX1_01 | 243 | 46 | 17758 | 2588 |
PAX6,ST13,HSPG2,CALB2,BIK,APOO,DHX8,BCL2L1,CDIPT,FAM167A,BCAP31,ZNF385B,MECOM,HDAC9,AKIRIN1,PAK6,SHC3,FAM160A2,SRR,IQCD,ABCD1,SCN2A,ZRANB1,RASGEF1A,CITED2,TPCN1,DNAI1,PVRL4,ACBD3,SPA17,PRICKLE1,IGSF8,PELI3,DUSP4,BBS2,PNKD,PITX2,GDE1,NAB2,FIBCD1,MDH1,EFNA1,DRP2,NRGN,F2RL1,CPEB2 |
| 3.576e-02 | -3.33 | CYT_DCMP_DEAMINASES_1 | prosite domains | PS00903 | 13 | 5 | 11866 | 1802 |
APOBEC3B,APOBEC3H,APOBEC3D,APOBEC3G,CDA |
| 3.578e-02 | -3.33 | human chr1q21 | chromosome location | human chr1q21 | 78 | 14 | 26250 | 2805 |
PIAS3,PSMB4,ARHGEF11,S100A11,BCL9,S100A4,S100A5,TDRKH,ANXA9,RFX5,S100A2,ARNT,S100A13,S100A6 |
| 3.579e-02 | -3.33 | sulfate activation for sulfonation | BIOCYC pathways | HUMAN_PWY-5340 | 2 | 2 | 907 | 172 |
PAPSS2,PAPSS1 |
| 3.579e-02 | -3.33 | L-lysine degradation XI (mammalian) | BIOCYC pathways | META_LYSINE-DEG1-PWY | 2 | 2 | 907 | 172 |
ALDH7A1,AASS |
| 3.579e-02 | -3.33 | sulfate activation for sulfonation | BIOCYC pathways | META_PWY-5340 | 2 | 2 | 907 | 172 |
PAPSS2,PAPSS1 |
| 3.579e-02 | -3.33 | gamma-glutamyl cycle | BIOCYC pathways | META_PWY-4041 | 2 | 2 | 907 | 172 |
GCLM,GCLC |
| 3.579e-02 | -3.33 | CMP-N-acetylneuraminate biosynthesis I (eukaryotes) | BIOCYC pathways | HUMAN_PWY-6138 | 2 | 2 | 907 | 172 |
CMAS,NANS |
| 3.579e-02 | -3.33 | lysine degradation I (saccharopine pathway) | BIOCYC pathways | HUMAN_LYSINE-DEG1-PWY | 2 | 2 | 907 | 172 |
ALDH7A1,AASS |
| 3.580e-02 | -3.33 | BIDUS_METASTASIS_UP | MSigDB lists | BIDUS_METASTASIS_UP | 207 | 40 | 17758 | 2588 |
RMND5A,DEPDC1,DLGAP5,RHBDL3,ERCC6L,PSMD10,CBLL1,RACGAP1,CCNB1,PCBP1,MNS1,CENPN,HMGXB4,FANCI,CKAP5,HSF2,CCNA2,PAK2,SLC35B4,PLK4,H2AFY,BUB1,MPHOSPH9,SMC4,SEC23A,CENPA,PBK,CDYL,WHSC1,NUSAP1,PPP1R14C,KIF11,NDRG3,NFIB,CDK1,PLOD2,AURKA,UBE2C,CCNB2,SRSF9 |
| 3.584e-02 | -3.33 | MAPKKK_CASCADE_GO_0000165 | MSigDB lists | MAPKKK_CASCADE_GO_0000165 | 102 | 22 | 17758 | 2588 |
MAP3K3,SPRED1,SOD1,TAOK2,CCM2,DUSP4,PKN1,MAP3K6,MAPK8IP1,MAPKAPK2,SCG2,SH2D3C,RGS3,MADD,KIAA1804,MAP3K9,MAP3K11,DUSP10,MDFIC,MAP3K5,CD81,MDFI |
| 3.584e-02 | -3.33 | CALCIUM_ION_BINDING | MSigDB lists | CALCIUM_ION_BINDING | 102 | 22 | 17758 | 2588 |
GCA,KCNIP3,MCTP1,HSP90B1,REPS2,SLC25A13,S100A4,CALM1,MCTP2,CALM3,NUCB2,HPCAL4,NCS1,CDK5R1,RCN1,CALR,CALM2,STIM1,CABP1,PKD2,S100A13,RASGRP1 |
| 3.585e-02 | -3.33 | V$CACBINDINGPROTEIN_Q6 | MSigDB lists | V$CACBINDINGPROTEIN_Q6 | 231 | 44 | 17758 | 2588 |
LASP1,KIF3C,SLC2A4,CDK17,RALBP1,ITGA6,ARL4C,TP53,UBE2Z,NOTCH2,RAB6A,SEPT4,PDGFB,SDC1,HPCAL4,SIX4,RALB,KCNS3,KNTC1,PIM1,CACNA1D,NCAM1,SMARCA2,FZD4,DCHS1,CBX6,KIF1C,PYGO1,PNKD,NFIX,MAGED2,CAMK2N2,RBM47,ACVRL1,ITPR1,NR4A3,PPP1CB,C1orf43,ARPC2,NRGN,USF2,RTN3,AHR,PKIA |
| 3.588e-02 | -3.33 | V$OCT1_04 | MSigDB lists | V$OCT1_04 | 225 | 43 | 17758 | 2588 |
PAX6,CPEB4,THRA,IRX4,GABRG2,NDUFA4,NOTCH2,BCL2L1,PPP2R3A,LMNA,HDAC9,CCND1,FOXP2,IRAK1,PTEN,XYLT2,LMO4,MITF,BCL6,KCNS3,TWIST1,DIXDC1,AHCY,TSPAN13,CACNA1D,NCAM1,MOXD1,SMARCA2,CASK,SH3BGRL,SERTAD4,LDB2,TMTC2,TP53INP2,NIN,NFIX,CNOT2,PITX2,RHOBTB2,SP6,ARF6,SHOX2,NR3C2 |
| 3.592e-02 | -3.33 | PLC beta mediated events | REACTOME pathways | R-HSA-112043 | 46 | 12 | 8202 | 1235 |
CALM2,PLA2G4A,ADRBK1,CALM1,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PLCB2,PRKAR1A |
| 3.592e-02 | -3.33 | Phospholipase C-mediated cascade; FGFR3 | REACTOME pathways | R-HSA-5654227 | 46 | 12 | 8202 | 1235 |
CALM2,PLCG1,ADRBK1,CALM1,FGF18,ITPR1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,PRKAR1A |
| 3.594e-02 | -3.33 | positive regulation of lamellipodium organization | biological process | GO:1902745 | 22 | 7 | 16441 | 2455 |
RAC2,NCKAP1,ARPC2,ARHGEF7,CORO1C,CORO1B,DNM2 |
| 3.594e-02 | -3.33 | peripheral nervous system axon ensheathment | biological process | GO:0032292 | 22 | 7 | 16441 | 2455 |
MPP5,SOD1,FA2H,ILK,AKT1,NDRG1,DAG1 |
| 3.594e-02 | -3.33 | regulation of cholesterol metabolic process | biological process | GO:0090181 | 22 | 7 | 16441 | 2455 |
SOD1,LDLRAP1,POR,PEX2,PRKAA1,ABCG1,SEC14L2 |
| 3.594e-02 | -3.33 | myelination in peripheral nervous system | biological process | GO:0022011 | 22 | 7 | 16441 | 2455 |
MPP5,SOD1,FA2H,ILK,AKT1,NDRG1,DAG1 |
| 3.599e-02 | -3.32 | positive regulation of DNA metabolic process | biological process | GO:0051054 | 156 | 32 | 16441 | 2455 |
ANXA3,GRHL2,FOXM1,PDGFB,PARM1,NPM2,CALR,TOP2A,PDGFA,E2F7,PCNA,CTNNB1,IGF1R,CST3,NEK2,BAX,MSH6,SIRT1,PDGFC,AKT1,RGCC,WHSC1,PRKCQ,AURKB,CD40,EGFR,KDM4D,NUDT16,INSR,AREG,STAT6,E2F8 |
| 3.602e-02 | -3.32 | N-cadherin signaling events | Pathway Interaction DB | ncadherinpathway | 33 | 12 | 2227 | 480 |
KIF5B,CALM2,PLCG1,RHOA,CTNNB1,CALM1,PIK3R1,PIK3CA,CALM3,CTNND1,CTTN,CAMK2G |
| 3.615e-02 | -3.32 | zf-C4 | pfam domains | PF00105 | 46 | 12 | 16629 | 2504 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR2C1,NR3C2,NR2C2 |
| 3.616e-02 | -3.32 | negative regulation of transport | biological process | GO:0051051 | 448 | 81 | 16441 | 2455 |
TXN,LGR4,THRA,SYTL4,BARD1,APC2,ERP29,IER3,CALM2,NOV,SP100,CABP1,DAB2IP,TWIST1,ACSL4,PACSIN1,F2R,CHP1,PPIF,ERLEC1,BAG4,AKT1,ACVR1C,DMTN,PTGER4,VPS4B,EZR,SLC25A5,PNKD,SNX12,ABR,IRS2,TRIM9,ENPP1,PTGS2,WWTR1,RAB11FIP1,CAB39,NRG1,ARF6,F2RL1,PACSIN2,NFKBIE,LGALS3,SERPINE2,PRKAA1,RAB23,CALM3,PSMD10,ANO9,FBLN1,ICAM1,WWP2,NEO1,GNB5,ADORA1,PTEN,PFKL,BMP7,UBE2J1,TMBIM6,MDFIC,ERBB3,MAPK7,MDFI,CALM1,LITAF,VAMP3,RGCC,PIM3,MAP1B,BANK1,NFKBIA,PKD2,YOD1,STK39,ITGAV,NDFIP1,TBC1D4,PKIA,PROM2 |
| 3.617e-02 | -3.32 | REACTOME_INTERFERON_GAMMA_SIGNALING | MSigDB lists | REACTOME_INTERFERON_GAMMA_SIGNALING | 58 | 14 | 17758 | 2588 |
HLA-B,JAK1,SP100,HLA-F,STAT1,IRF2,IRF7,OAS3,HLA-C,NCAM1,ICAM1,HLA-A,IRF1,SOCS3 |
| 3.617e-02 | -3.32 | PID_ATF2_PATHWAY | MSigDB lists | PID_ATF2_PATHWAY | 58 | 14 | 17758 | 2588 |
CCND1,RB1,HES1,CCNA2,SERPINB5,DUSP10,H2AFY,MAPK11,BCL2L1,FOS,DUSP5,CSRP2,DUSP1,SOCS3 |
| 3.617e-02 | -3.32 | BIOCARTA_HIVNEF_PATHWAY | MSigDB lists | BIOCARTA_HIVNEF_PATHWAY | 58 | 14 | 17758 | 2588 |
CASP3,RB1,BAG4,CASP7,TRAF2,PAK2,NFKBIA,CASP9,XIAP,ARHGDIB,MAP3K5,LMNA,RASA1,FAS |
| 3.617e-02 | -3.32 | LEE_LIVER_CANCER_DENA_UP | MSigDB lists | LEE_LIVER_CANCER_DENA_UP | 58 | 14 | 17758 | 2588 |
SPP1,CD63,NDRG1,GPC3,SOX9,KDELR3,COL4A5,TAGLN2,NOTCH3,LGMN,PTPRE,CPE,KIF11,LEPR |
| 3.623e-02 | -3.32 | CCND1 (cyclin D1) | protein interactions | 595 | 94 | 22 | 16036 | 2547 |
THRB,CDKN1C,THRA,CALM1,MYBL2,CUL1,HERC5,NPDC1,PRKACA,CDK1,EGFR,CCND1,TP73,RB1,NCOA3,PCNA,CTNNB1,RBL1,PPP1CB,HDAC1,CDKN1B,MAPK11 |
| 3.627e-02 | -3.32 | GRB10 (growth factor receptor bound protein 10) | protein interactions | 2887 | 39 | 11 | 16036 | 2547 |
IRS2,FYN,INSR,IGF1R,AKT1,RET,PIK3R1,ELK1,EGFR,GIGYF1,DENND5B |
| 3.627e-02 | -3.32 | PPP6C (protein phosphatase 6, catalytic subunit) | protein interactions | 5537 | 39 | 11 | 16036 | 2547 |
NFKBIE,AURKA,TGFBR1,AURKB,FBXO6,MAP3K7,ILK,TIPRL,PPP6R1,VCP,EGFR |
| 3.627e-02 | -3.32 | human chrXq22.2 | chromosome location | human chrXq22.2 | 18 | 5 | 26250 | 2805 |
FAM199X,NGFRAP1,TMSB15B,WBP5,TCEAL4 |
| 3.627e-02 | -3.32 | human chr5q13 | chromosome location | human chr5q13 | 18 | 5 | 26250 | 2805 |
RAD17,F2R,F2RL1,HEXB,MAP1B |
| 3.634e-02 | -3.31 | CALR (calreticulin) | protein interactions | 811 | 115 | 26 | 16036 | 2547 |
HSP90B1,ENO2,LGR4,NR3C1,HLA-E,SUZ12,TAP1,EZR,PDIA3,CD40,PRKACA,ITGA2B,HLA-A,VCP,EGFR,ELF3,RCN1,CALR,TAPBP,PCNA,ITGA3,P4HB,ITGAV,HLA-C,LRIF1,HSPB1 |
| 3.640e-02 | -3.31 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_DN | 154 | 31 | 17758 | 2588 |
TGIF1,LOC81691,MPZL1,CDCA3,OSR2,BCL7B,STK17B,TSPAN7,MOCS1,RND1,PDE11A,MYO5C,IRS2,MDK,PTGS2,ANKS1B,CYP4F11,PLOD2,FOSB,FAM83D,DNM2,ZDHHC23,ZNF165,TWIST1,NR4A2,GEM,ZRANB1,NFKB2,SLC25A38,TIPARP,NIPA1 |
| 3.640e-02 | -3.31 | NITROGEN_COMPOUND_METABOLIC_PROCESS | MSigDB lists | NITROGEN_COMPOUND_METABOLIC_PROCESS | 154 | 31 | 17758 | 2588 |
B3GALT6,GCLM,ALDH6A1,AKT1,NQO1,GNPDA1,DHPS,GUSB,GCLC,GNE,XYLT1,ASL,ETNK1,SLC7A2,SPR,EXT2,EGFR,CHST2,GLCE,GNS,DDAH1,SLC6A6,ALDH5A1,UAP1,P4HB,CSGALNACT1,GOT1,GLA,GAD1,MCCC2,FAH |
| 3.646e-02 | -3.31 | CCTGTGA,MIR-513 | MSigDB lists | CCTGTGA,MIR-513 | 125 | 26 | 17758 | 2588 |
SERTAD4,CALM1,BNIP3L,PSMD10,CALM3,WHSC1,BLCAP,SYP,CNTNAP2,SNN,PRX,CALM2,CCND1,BTG1,ADD3,DPYSL2,CSNK1G1,PGM2L1,CTNND1,RGS5,CRY2,PDXK,MAPK7,ARHGEF9,DMPK,CYP1B1 |
| 3.649e-02 | -3.31 | positive regulation of apoptotic signaling pathway | biological process | GO:2001235 | 185 | 37 | 16441 | 2455 |
PINK1,NKX3-1,BMF,TRAF2,BIK,RET,TP53,PDIA3,TGFBR1,BCL2L1,SEPT4,BCAP31,TP73,TFAP4,SRPX,CTSC,PTEN,SIVA1,PAK2,BAX,PLEKHF1,DAB2IP,BUB1,TNFRSF12A,PPP1CA,ITM2C,SIRT1,PPIF,SOD1,AKT1,PLAUR,PRKRA,FAS,BCL10,DNM1L,E2F1,GPER1 |
| 3.656e-02 | -3.31 | salivary_gland-carcinoma-acinic_cell_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-acinic_cell_carcinoma | 18 | 6 | 17775 | 2585 |
ERBB2,CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 3.656e-02 | -3.31 | salivary_duct_carcinoma | COSMIC cancer mutations | salivary_duct_carcinoma | 18 | 6 | 17775 | 2585 |
ERBB2,CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 3.658e-02 | -3.31 | regulation of cartilage development | biological process | GO:0061035 | 62 | 15 | 16441 | 2455 |
BMP2,RUNX2,CTNNB1,CTGF,CYR61,ACVRL1,SOX9,FGF18,BMP1,TGFBR1,LOXL2,SHOX2,FAM101B,POR,RARG |
| 3.658e-02 | -3.31 | positive regulation of endothelial cell migration | biological process | GO:0010595 | 62 | 15 | 16441 | 2455 |
ANXA3,PTGS2,PLCG1,AKT1,PLPP3,FGF18,GATA3,PDGFB,ETS1,BCAR1,HSPB1,SRPX2,NRP2,HDAC9,GPLD1 |
| 3.674e-02 | -3.30 | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | MSigDB lists | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | 91 | 20 | 17758 | 2588 |
PLA2G4A,WASF3,AKT1,INPP5D,PIK3R1,PLD2,PLCG1,RAC2,VASP,DNM1L,LIMK1,PLCG2,DNM2,PIK3CA,PLD1,PIK3CD,PIKFYVE,ARF6,ARPC2,SYK |
| 3.676e-02 | -3.30 | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | 372 | 67 | 17758 | 2588 |
KLK10,TRIP10,CAST,IL18,MAPK4,OSR2,BCL2L1,SNN,SPSB1,KREMEN1,TNFSF9,IER3,NKAIN3,TP73,ANKS6,IFIT1,OAS3,ARL4D,NFKB2,FGFR1OP2,SPEF2,CD55,CAPN6,FZD4,USP18,RNF19B,PTGS2,BHLHB9,KLF5,IRF7,HS3ST3B1,TTC9,MAFF,COBL,DDX58,NKX3-1,SDC4,HAL,ELOVL7,HERC5,DUSP5,ICAM1,ELF3,FOXP2,ZFX,ITGB8,GPC3,MCF2L,DRAM1,MAPK11,ATP2B1,EPB41L5,ADAM17,RAB3B,PLAUR,RAPGEF2,LITAF,IFIT3,TP53INP2,GPLD1,IL1R1,SEC14L4,HTT,MFSD2A,AGBL5,DRP2,IFIH1 |
| 3.677e-02 | -3.30 | glycolipid metabolic process | biological process | GO:0006664 | 111 | 24 | 16441 | 2455 |
PIGC,UGT8,PLAUR,HEXB,ASAH1,ARSK,PIGL,PGAP1,CPTP,GPLD1,B4GALNT1,ALDH5A1,ITGB8,ARSG,A4GALT,BAX,GLB1,CTSA,GLA,ARSB,ST3GAL1,NAGA,GM2A,KDELC2 |
| 3.677e-02 | -3.30 | positive regulation of endocytosis | biological process | GO:0045807 | 111 | 24 | 16441 | 2455 |
CD63,ANO6,FLOT1,CBLL1,CAMK1D,CBL,MERTK,PICK1,ABR,CALR,LDLRAP1,GATA2,AXL,GPC3,PLCG2,DNM2,NOD2,ARRB1,ITGAV,WNT3A,TSPAN1,F2RL1,RAP1GAP,SYK |
| 3.686e-02 | -3.30 | non_functioning | COSMIC cancer mutations | non_functioning | 244 | 46 | 17775 | 2585 |
DOC2A,TCF25,KIAA1462,PARP14,RET,ARFGEF1,TP53,ZNRF3,SAMD9,TRIM68,HDAC9,CDKN2C,RB1,MUC16,CTNNB1,CDH1,GRHL1,PTEN,SLC30A6,PIK3CA,FNIP1,GYS1,KNTC1,CACNA1D,ZNF462,GCC2,CEP89,TMTC2,NUBP1,MAP1B,DPYSL3,GNAS,NUCB1,BANK1,PTPRJ,ATP1A1,DCK,RAET1L,SECTM1,NXPH4,PLXND1,MAP3K5,TANC2,MELK,PRKAR1A,DOCK9 |
| 3.688e-02 | -3.30 | primary cilium | cellular component | GO:0072372 | 206 | 40 | 17570 | 2579 |
DYNLRB1,KIF3C,USH1C,TCTN2,C5orf30,IFT27,MERTK,DHRS3,TTC21B,RAB15,INPP5E,ADRBK1,GNB5,IQCE,OCRL,SMO,TUBG1,RP2,CNGA1,MYRIP,RPGR,GPR161,MYO5A,B9D2,CEP89,CYS1,CCSAP,SPA17,NPHP3,GNA11,MAP1B,RGS9,PROM1,PHLPP2,WDR19,TRAF3IP1,PKD2,SPTBN5,CEP41,DRD1 |
| 3.690e-02 | -3.30 | KANG_DOXORUBICIN_RESISTANCE_DN | MSigDB lists | KANG_DOXORUBICIN_RESISTANCE_DN | 18 | 6 | 17758 | 2588 |
WWP1,NCOA3,NR1D2,NFAT5,ATP2B1,PCYOX1 |
| 3.690e-02 | -3.30 | SCHEIDEREIT_IKK_TARGETS | MSigDB lists | SCHEIDEREIT_IKK_TARGETS | 18 | 6 | 17758 | 2588 |
CCND1,NCOA3,NFKB2,CTNNB1,NFKBIA,BCL10 |
| 3.690e-02 | -3.30 | TUBE_DEVELOPMENT | MSigDB lists | TUBE_DEVELOPMENT | 18 | 6 | 17758 | 2588 |
GCLM,SOD1,KCNMB4,GCLC,LMO4,BCL10 |
| 3.690e-02 | -3.30 | SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS | MSigDB lists | SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS | 18 | 6 | 17758 | 2588 |
HS6ST1,GCLM,HS3ST3B1,GCLC,CSGALNACT1,GLCE |
| 3.690e-02 | -3.30 | BIOCARTA_TEL_PATHWAY | MSigDB lists | BIOCARTA_TEL_PATHWAY | 18 | 6 | 17758 | 2588 |
RB1,IGF1R,AKT1,EGFR,TP53,TEP1 |
| 3.690e-02 | -3.30 | REACTOME_SYNTHESIS_OF_PC | MSigDB lists | REACTOME_SYNTHESIS_OF_PC | 18 | 6 | 17758 | 2588 |
SLC44A2,PHOSPHO1,LPIN3,CHPT1,SLC44A1,SLC44A3 |
| 3.690e-02 | -3.30 | DAZARD_UV_RESPONSE_CLUSTER_G28 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G28 | 18 | 6 | 17758 | 2588 |
TACSTD2,PTGS2,CTGF,CITED2,H1FX,IER3 |
| 3.690e-02 | -3.30 | BIOCARTA_ETS_PATHWAY | MSigDB lists | BIOCARTA_ETS_PATHWAY | 18 | 6 | 17758 | 2588 |
ETS2,FOS,RBL1,ETS1,CSF1,E2F1 |
| 3.690e-02 | -3.30 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | MSigDB lists | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | 18 | 6 | 17758 | 2588 |
B4GALT3,B4GALT4,MGAT4A,MGAT5,FUT8,MGAT4B |
| 3.690e-02 | -3.30 | LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP | MSigDB lists | LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP | 18 | 6 | 17758 | 2588 |
GALNT3,ACSL4,NPNT,KCNN4,CD82,WBP5 |
| 3.690e-02 | -3.30 | HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2 | MSigDB lists | HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2 | 18 | 6 | 17758 | 2588 |
TOP2A,CCND1,CCNA2,CCNB1,EGFR,TP53 |
| 3.690e-02 | -3.30 | OUYANG_PROSTATE_CANCER_PROGRESSION_UP | MSigDB lists | OUYANG_PROSTATE_CANCER_PROGRESSION_UP | 18 | 6 | 17758 | 2588 |
AVPI1,JAK1,FOS,CD81,SYK,STAT1 |
| 3.690e-02 | -3.30 | EARLY_ENDOSOME | MSigDB lists | EARLY_ENDOSOME | 18 | 6 | 17758 | 2588 |
WDFY1,LDLRAP1,CTNS,NF2,DNER,STEAP2 |
| 3.690e-02 | -3.30 | MODULE_294 | MSigDB lists | MODULE_294 | 18 | 6 | 17758 | 2588 |
ACADM,CA2,ACADSB,CA8,HAL,CTH |
| 3.690e-02 | -3.30 | KOBAYASHI_EGFR_SIGNALING_6HR_DN | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_6HR_DN | 18 | 6 | 17758 | 2588 |
CCND1,DUSP4,CYR61,MAFF,DUSP5,IER3 |
| 3.690e-02 | -3.30 | ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | MSigDB lists | ESTABLISHMENT_OF_ORGANELLE_LOCALIZATION | 18 | 6 | 17758 | 2588 |
SUN2,NUSAP1,CENPE,AP1M2,SHROOM2,CDCA5 |
| 3.690e-02 | -3.30 | SPINDLE_POLE | MSigDB lists | SPINDLE_POLE | 18 | 6 | 17758 | 2588 |
TUBG1,BUB1,KNTC1,DLGAP5,NDE1,KIF11 |
| 3.693e-02 | -3.30 | Signaling events mediated by VEGFR1 and VEGFR2 | Pathway Interaction DB | vegfr1_2_pathway | 63 | 20 | 2227 | 480 |
RHOA,AKT1,EPAS1,IQGAP1,PIK3R1,CALM1,CALM3,YES1,PRKACA,NRP2,CALM2,PLCG1,FYN,CTNNB1,PIK3CA,MAPK11,ITGAV,HSPB1,GAB1,ARNT |
| 3.700e-02 | -3.30 | cilium organization | biological process | GO:0044782 | 191 | 38 | 16441 | 2455 |
TTC8,CFAP74,TCTN2,AK7,POC1B,RAB23,CCNO,ZMYND10,IFT27,MNS1,SSX2IP,TTC21B,LRRC6,OCRL,SNX10,RPGR,TTLL1,DNAI1,DNAAF3,SPEF2,LCA5,CELSR2,B9D2,CFAP46,CEP89,FOPNL,RAB3IP,BBS2,SPAG1,DZIP1L,CEP162,ONECUT1,PVRL2,TRAF3IP1,WDR19,SSNA1,CEP41,EHD1 |
| 3.701e-02 | -3.30 | MODULE_192 | MSigDB lists | MODULE_192 | 108 | 23 | 17758 | 2588 |
MYO5B,PCCB,GCLM,FRMD4A,LGALS8,NBPF3,OSGIN2,COL4A5,KIF13A,DUSP4,CCNB1,DHRS3,SPTLC2,PCTP,DCAF10,OSBPL2,HS6ST1,NUP210,TIMP1,BHLHE41,TMEM143,AK3,ESYT2 |
| 3.701e-02 | -3.30 | LAIHO_COLORECTAL_CANCER_SERRATED_UP | MSigDB lists | LAIHO_COLORECTAL_CANCER_SERRATED_UP | 108 | 23 | 17758 | 2588 |
PLA2G4A,PDGFC,ELK3,CTSB,IQGAP1,BNIP3L,EMP3,PLS1,ATP1B1,MORF4L2,OPTN,CTGF,DPYSL2,IL6ST,TAGLN2,NPTN,ARPC2,PDIA6,SGCB,MYL12B,CSRP2,ATP2B1,PRKAR1A |
| 3.702e-02 | -3.30 | WHTH_DNA-bd_dom | interpro domains | IPR011991 | 213 | 41 | 18293 | 2672 |
ELK4,RECQL,PAX6,DEPDC1,FOXM1,SHPRH,ETV5,CUL4B,CUL1,ETS1,H1FX,ELF3,FOXP2,E2F7,HSF2,ELF5,GTF2F2,IRF2,RFX5,PIKFYVE,ETV7,ETV4,DVL2,HP1BP3,METAP2,ELK3,DEPDC4,FOXJ2,ELK1,FOXL1,FOXD2,HSF4,RGS9,ETS2,H1F0,PSMD3,E2F1,IRF7,E2F8,FOXA1,IRF1 |
| 3.704e-02 | -3.30 | cGMP-PKG signaling pathway | KEGG pathways | ko04022 | 167 | 35 | 6908 | 1076 |
MYL9,PPP1R12A,CALM3,ITPR2,CALM2,VASP,ADORA1,PIK3CA,PRKG1,PIK3CD,CNGA1,PPP1CA,CACNA1D,PLCB2,ATP2B1,PPIF,RHOA,AKT1,PIK3R1,CALM1,PDE5A,ATP1B1,ITPR3,SLC25A5,GNA11,EDNRA,IRS2,KCNMB4,INSR,ATP1A1,SLC25A4,MYLK,ITPR1,PPP1CB,ATP1B3 |
| 3.704e-02 | -3.30 | cGMP-PKG signaling pathway | KEGG pathways | hsa04022 | 167 | 35 | 6908 | 1076 |
MYL9,PPP1R12A,CALM3,ITPR2,CALM2,VASP,ADORA1,PIK3CA,PRKG1,PIK3CD,CNGA1,PPP1CA,CACNA1D,PLCB2,ATP2B1,PPIF,RHOA,AKT1,PIK3R1,CALM1,PDE5A,ATP1B1,ITPR3,SLC25A5,GNA11,EDNRA,IRS2,KCNMB4,INSR,ATP1A1,SLC25A4,MYLK,ITPR1,PPP1CB,ATP1B3 |
| 3.714e-02 | -3.29 | positive regulation of cell-substrate adhesion | biological process | GO:0010811 | 100 | 22 | 16441 | 2455 |
EPB41L5,FMN1,DMTN,ARHGEF7,SDC4,UTRN,EPHA1,ILK,FBLN1,EMP2,CALR,SPP1,TSC1,PTPRJ,ITGA3,CYR61,NPNT,CSF1,DNM2,TRIOBP,ARPC2,COL16A1 |
| 3.715e-02 | -3.29 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP | 166 | 33 | 17758 | 2588 |
ST13,CHCHD7,CYP2J2,SCML1,IGF1R,IL6ST,BDH1,PASK,TPST1,CD9,FAM102A,PIK3CD,SNED1,LAMP3,SUSD3,ZWINT,ACVR1C,ADCK3,DCHS1,CR2,EPHA1,MEST,TYSND1,LDLRAP1,NGFRAP1,SPINT2,CDCA7L,TTC9,SOX8,NDFIP1,FAM134B,ARHGEF4,KLF7 |
| 3.717e-02 | -3.29 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | 69 | 16 | 17758 | 2588 |
PSRC1,ISYNA1,CCNB1,NUCB2,DDR1,PROM1,CDH1,NGFRAP1,GPC3,BMP7,TNFRSF12A,UNC5B,UBE2C,MAFF,IGDCC4,PROM2 |
| 3.726e-02 | -3.29 | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | MSigDB lists | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | 80 | 18 | 17758 | 2588 |
PLA2G4A,CDS2,LPGAT1,PNPLA2,ETNK1,PHOSPHO1,PLD2,PLA2G16,LPIN3,CDIPT,CDS1,SLC44A3,AGPAT2,SLC44A1,DGAT2,SLC44A2,PLD1,CHPT1 |
| 3.730e-02 | -3.29 | Adipocytokine signaling pathway | KEGG pathways | hsa04920 | 70 | 17 | 6908 | 1076 |
PRKAA2,ACACB,SLC2A4,AKT1,NFKBIE,CAMKK1,TRAF2,PRKAA1,PPARA,PRKCQ,LEPR,SOCS3,IRS2,PRKAG2,NFKBIA,ADIPOR1,ACSL4 |
| 3.730e-02 | -3.29 | Adipocytokine signaling pathway | KEGG pathways | ko04920 | 70 | 17 | 6908 | 1076 |
PRKAA2,ACACB,SLC2A4,AKT1,NFKBIE,CAMKK1,TRAF2,PRKAA1,PPARA,PRKCQ,LEPR,SOCS3,IRS2,PRKAG2,NFKBIA,ADIPOR1,ACSL4 |
| 3.735e-02 | -3.29 | proteasome complex | cellular component | GO:0000502 | 74 | 17 | 17570 | 2579 |
PSMB4,DNAJB2,AMFR,PSME2,PSMD7,PSMD10,PSME1,PSMA4,VCP,RAD23A,IDE,PSMD1,PSMD3,PSMC2,HSPB1,PSMC1,PSMA5 |
| 3.735e-02 | -3.29 | JUP (junction plakoglobin) | protein interactions | 3728 | 110 | 25 | 16036 | 2547 |
ST13,NFKBIE,RBM24,CUL4B,FHL2,PKP2,ERBB2,GMCL1,NENF,ZFYVE9,EGFR,DPYSL3,PTPRF,CTNNBIP1,FYN,PTPRJ,CTNNB1,CDH1,PLOD2,MSH2,IARS2,CDH3,CTNND1,USP1,MAPK7 |
| 3.752e-02 | -3.28 | spleen | COSMIC cancer mutations | spleen | 423 | 75 | 17775 | 2585 |
LMO7,NMRK1,SORBS1,UPF3B,FAM129B,IQGAP1,CACNA2D2,TP53,ERBB2,CUL1,CD274,SPTB,CCND1,CTNNB1,SH3BP1,TACC2,MKRN3,BCL6,OAS3,MYO5B,CPD,ITCH,UTRN,CLCN2,NIN,STAT6,SPTBN5,ARHGAP4,REEP4,SORT1,CDK17,PARP14,CDCA8,NOTCH2,DOCK11,NRP2,PDIA4,CALR,RB1,TAF1B,PTEN,TUBGCP6,SRP54,SORL1,PIM1,ZNF117,GPR161,ABCC1,IGDCC4,SPATA20,SHMT1,FMN1,PARD3B,PTPRH,OGDHL,WHSC1,AK4,PYGL,COL7A1,FBXO10,RASA1,EPN3,DHDH,SWAP70,FAT4,COL13A1,CCDC6,PELI2,TMEM30A,DYSF,OSCP1,MAP3K5,NDFIP1,COL16A1,DMPK |
| 3.774e-02 | -3.28 | cofactor binding | molecular function | GO:0048037 | 257 | 49 | 16491 | 2452 |
ALDH6A1,CRYM,GCAT,OAT,AIFM2,SPR,PDXDC1,SGPL1,ALDH1A3,SRR,AOX1,ECI2,HMGCL,CRY2,GOT1,AHCY,ACOX2,ACAD8,GAD1,CTH,SIRT1,SOAT1,ACBD5,PRODH,SHMT1,AGPS,ACBD3,GCLC,OGDHL,CCBL2,PYGL,IDH1,SPTLC2,TP53I3,POR,DUOX1,MARC1,ACADSB,ACAD10,DBI,MAOA,DHTKD1,MDH1,ACADM,PDXK,AIFM3,CTBP1,ACOT7,XDH |
| 3.777e-02 | -3.28 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP | 466 | 82 | 17758 | 2588 |
S100A11,PSME2,PTTG1,NDC80,TP53,RGS20,IL27RA,NENF,GRK6,MORF4L2,STIM1,DPYSL2,TAX1BP3,KIF22,CTTN,TECR,PHKA2,GPX4,CKS2,VPS11,TAF5,TCEB2,CDC20,SERTAD3,NFE2L1,EZR,CR2,ARHGDIB,ICMT,CCNF,H2AFV,ATP1A1,ACYP1,KCNK1,PNPLA6,HDAC1,RGS14,HSPB1,RTN3,MAPK12,ALDH6A1,PEX6,CENPI,ETV5,AES,PKN1,COX6C,ZNF212,WWP2,SGPL1,CALR,TOP2A,DAZAP1,VASP,CD22,RPL39,FDXR,CST3,BAX,GTF2F2,ZDHHC13,ATP8B1,ACTA2,CD70,AHCY,CNPY3,DDB2,HES1,ZNF84,KIF20A,TESK1,SPA17,TCF7,HTT,DBI,SLC2A6,AURKA,PKD2,UBE2C,AHR,ACOT7,RAD21 |
| 3.777e-02 | -3.28 | SESTO_RESPONSE_TO_UV_C2 | MSigDB lists | SESTO_RESPONSE_TO_UV_C2 | 53 | 13 | 17758 | 2588 |
KIF5B,ANXA3,FNTA,PLSCR1,TRIP10,NR3C1,GCLC,ATP13A3,TFAP2A,ERBB3,DUSP4,CTDSP2,RAD21 |
| 3.777e-02 | -3.28 | KEGG_VIBRIO_CHOLERAE_INFECTION | MSigDB lists | KEGG_VIBRIO_CHOLERAE_INFECTION | 53 | 13 | 17758 | 2588 |
GNAS,PLCG1,ATP6V0B,SEC61B,SEC61G,PLCG2,ATP6V1E2,KDELR3,ATP6V1C1,PRKACA,SLC12A2,KDELR1,PDIA4 |
| 3.777e-02 | -3.28 | IKEDA_MIR1_TARGETS_UP | MSigDB lists | IKEDA_MIR1_TARGETS_UP | 53 | 13 | 17758 | 2588 |
SPRED1,ACVR1,PDCD10,GPRC5B,GCLC,PLK2,CORO1C,RRBP1,FNDC3A,CITED2,NFAT5,ARF4,FZD7 |
| 3.777e-02 | -3.28 | REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE | MSigDB lists | REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE | 53 | 13 | 17758 | 2588 |
CALM2,PLCG1,ADRBK1,FGFR2,CALM1,FGF18,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,FGF19,PRKAR1A |
| 3.778e-02 | -3.28 | Herpes simplex infection | KEGG pathways | hsa05168 | 184 | 38 | 6908 | 1076 |
DDX58,CASP3,IL15,HLA-E,HLA-F,TRAF2,TAP1,TP53,CUL1,TAF6L,HLA-A,PER2,SP100,IFIT1,OAS3,PPP1CA,HLA-C,MAP3K7,EEF1D,TAF5,EIF2AK1,SRSF5,FOS,CDK1,SOCS3,FAS,HLA-B,JAK1,PVRL2,NFKBIA,STAT1,PPP1CB,IRF7,RNASEL,PER3,IFIH1,TRAF5,SRSF9 |
| 3.778e-02 | -3.28 | Herpes simplex infection | KEGG pathways | ko05168 | 184 | 38 | 6908 | 1076 |
DDX58,CASP3,IL15,HLA-E,HLA-F,TRAF2,TAP1,TP53,CUL1,TAF6L,HLA-A,PER2,SP100,IFIT1,OAS3,PPP1CA,HLA-C,MAP3K7,EEF1D,TAF5,EIF2AK1,SRSF5,FOS,CDK1,SOCS3,FAS,HLA-B,JAK1,PVRL2,NFKBIA,STAT1,PPP1CB,IRF7,RNASEL,PER3,IFIH1,TRAF5,SRSF9 |
| 3.782e-02 | -3.28 | positive regulation of nuclear division | biological process | GO:0051785 | 57 | 14 | 16441 | 2455 |
PLK1,NPM2,RB1,INSR,DLGAP5,IGF1R,PTEN,CDCA5,RGCC,AURKA,NUSAP1,PDGFB,UBE2C,ESPL1 |
| 3.788e-02 | -3.27 | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 184 | 36 | 17758 | 2588 |
CCNE2,NUDT6,FRMD6,CENPI,CORO1B,MAGOHB,CCNA2,SIVA1,BDH1,CEP78,CAPG,LRP11,PSMA5,CRTAP,MSH6,CERS2,CKS2,SHMT1,CCDC34,GLO1,BLVRA,XRCC6BP1,RNPEP,LEPR,PRDX4,LRRC42,SLCO4A1,ANKRD6,WIPI1,PRCP,PGRMC1,KIAA1804,MDH1,NUP37,APOL2,STARD3NL |
| 3.788e-02 | -3.27 | RAPA_EARLY_UP.V1_DN | MSigDB lists | RAPA_EARLY_UP.V1_DN | 184 | 36 | 17758 | 2588 |
GRN,PINK1,CDH22,HLA-E,CIT,WDTC1,FLOT1,MGST2,HDAC6,CACNB4,LGALS3BP,LMNA,SNTA1,PHYHIP,NUP210,GALNS,TFAP2A,CRY2,EPHB4,FARP2,NAGPA,CRIP2,NFE2L1,GRIN1,SNTB1,MFSD7,OSBPL2,AXL,WFS1,LRIG1,OVOL1,PLXND1,ZBTB6,PLIN3,ARHGAP4,CBX4 |
| 3.790e-02 | -3.27 | V$ATF4_Q2 | MSigDB lists | V$ATF4_Q2 | 250 | 47 | 17758 | 2588 |
LTBP1,BMF,SORBS1,CAPN12,TSC22D3,PSMD7,NDRG2,BAHD1,PRR7,TIPRL,FAM167A,IRF2BPL,AKIRIN1,PAK6,CXCL16,ZNF687,PPP1R10,STIM1,LMO4,FOSB,ABCA2,SGK1,ABCD1,RFX5,PDE4D,RASGEF1A,HP1BP3,DUSP1,CAPN6,PTPRU,PRICKLE1,ZFAND5,FOS,KDM3A,CDK5R1,PITX2,GNAS,CAMK2N2,TMEM54,NR4A3,MPP2,MAOA,NR4A2,CENPE,GEM,AHR,PKIA |
| 3.795e-02 | -3.27 | CLEC7A (C-type lectin domain family 7, member A) | protein interactions | 64581 | 21 | 7 | 16036 | 2547 |
CALM3,AIP,TMPRSS4,KTN1,RANBP9,OCLN,BNIP3L |
| 3.795e-02 | -3.27 | CENPE (centromere protein E) | protein interactions | 1062 | 21 | 7 | 16036 | 2547 |
CUL1,BUB1,NUF2,CENPE,CBX4,PRC1,PSMD7 |
| 3.795e-02 | -3.27 | ATP2B1 (ATPase, Ca++ transporting, plasma membrane 1) | protein interactions | 490 | 21 | 7 | 16036 | 2547 |
ERBB2IP,ATP1A1,LGR4,PRKACA,GNB2,CALM1,EGFR |
| 3.795e-02 | -3.27 | PI4KA (phosphatidylinositol 4-kinase, catalytic, alpha) | protein interactions | 5297 | 21 | 7 | 16036 | 2547 |
HLA-B,PITPNA,TGOLN2,CD274,HLA-C,MRPL44,STRN4 |
| 3.795e-02 | -3.27 | DOK3 (docking protein 3) | protein interactions | 79930 | 21 | 7 | 16036 | 2547 |
DPP9,FYN,LRRK1,DPP8,INPP5D,RET,UHRF1BP1L |
| 3.795e-02 | -3.27 | MAPK15 (mitogen-activated protein kinase 15) | protein interactions | 225689 | 21 | 7 | 16036 | 2547 |
MBP,PCNA,MAP1LC3B,NR3C1,ESYT2,MAPK12,GABARAPL1 |
| 3.795e-02 | -3.27 | MPP1 (membrane protein, palmitoylated 1) | protein interactions | 4354 | 21 | 7 | 16036 | 2547 |
AMOTL2,ERBB2IP,DNPEP,STK38,RPS6KA1,SMN1,OPTN |
| 3.795e-02 | -3.27 | DCUN1D5 (DCN1, defective in cullin neddylation 1, domain containing 5) | protein interactions | 84259 | 21 | 7 | 16036 | 2547 |
CUL1,FAM177A1,TLN2,LYPD3,PNKD,CUL4B,SAC3D1 |
| 3.795e-02 | -3.27 | MCCC2 (methylcrotonoyl-CoA carboxylase 2) | protein interactions | 64087 | 21 | 7 | 16036 | 2547 |
HMGCL,IFIT1,INPPL1,LGALS3,UBASH3B,HDAC11,MCCC1 |
| 3.795e-02 | -3.27 | SH3RF1 (SH3 domain containing ring finger 1) | protein interactions | 57630 | 21 | 7 | 16036 | 2547 |
ADAM15,RACGAP1,AKT1,PAK2,MAP3K11,SH3RF2,MAP3K9 |
| 3.795e-02 | -3.27 | IGF2 (insulin-like growth factor 2) | protein interactions | 3481 | 21 | 7 | 16036 | 2547 |
NOV,IGFBP2,INSR,IDE,IGF1R,IGFBP6,GPC3 |
| 3.802e-02 | -3.27 | V$AREB6_02 | MSigDB lists | V$AREB6_02 | 244 | 46 | 17758 | 2588 |
SCN5A,BMF,CAMKK1,IRX4,IL13RA1,BCL2L1,FAM81A,DDR1,NRP2,WWP2,IRF2BPL,ITGA3,LLGL2,TMEM62,BCL6,VAT1,USP1,TAGLN2,ERBB3,EGLN3,DGKG,TSPAN33,TUBA4A,PVRL4,DOCK4,PCDH1,WNT10B,PIK3R1,SPA17,KBTBD8,TMEM151A,KIF13A,FOS,LCP1,PITX2,PPP2R4,PGM2L1,EFNA1,MAP3K5,OSR1,DRP2,SEMA3A,OCLN,FOXA1,DMPK,RGMA |
| 3.804e-02 | -3.27 | GSE17721_0.5H_VS_12H_LPS_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_12H_LPS_BMDM_UP | 190 | 37 | 17758 | 2588 |
TPRN,SLC25A13,ELOVL7,GMPR,TESK2,MRAS,SORBS3,FAM198B,NUCB2,FAM81A,LTBP3,KIAA1161,XPR1,H1FX,CDKN2C,FAM111A,PCNA,IL6ST,BDH1,OPN3,TRIM3,ABCD1,TSPAN13,TECR,GPX4,SEC61B,GUSB,ARHGDIB,CYP4F3,CDK1,ZMPSTE24,DHX32,ENPP1,RAB31,NR4A3,PPP2R2D,CSRP2 |
| 3.804e-02 | -3.27 | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDM_UP | 190 | 37 | 17758 | 2588 |
CCNI,DYNLRB1,PARP12,IQGAP1,DHX8,EFHD2,POMGNT1,CMTM6,SIRPA,XPR1,PLS3,GATA2,CTSC,CD9,CRY2,TECR,IL1RAP,SOCS5,B3GNT2,HMGN5,LGALS8,MGAT4B,PARP4,RNPEP,SPTLC2,DGKE,CNOT2,CARHSP1,AP1AR,MSL1,JAK1,P4HA2,PLA2G15,CDCA7L,GDF11,SLC25A30,HIPK3 |
| 3.804e-02 | -3.27 | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN | MSigDB lists | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN | 190 | 37 | 17758 | 2588 |
CCNE2,SLC25A24,MRPL44,PLSCR4,IQGAP1,ARMC7,CUL1,SLC36A4,MAP1LC3B,STIL,VASP,DPYSL2,RPL39,AIM1,PIK3CA,DUSP10,ECI2,SRP54,TSPAN13,F2R,MED30,SULF2,TGIF1,ASPM,MPP1,TCF7,GALNT3,PPP2R5A,STAT6,DCK,CDCA5,NLRC5,PPP1CB,NR4A2,ATP1B3,ARSB,TMEM131 |
| 3.804e-02 | -3.27 | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | 190 | 37 | 17758 | 2588 |
EXPH5,CCNI,UGP2,PAPSS2,EPS8,ITPR2,DPP8,SEPP1,PSMD1,PSMC2,GCNT1,MOB4,PHF20L1,MCTP1,LGALS8,DENND1B,RC3H2,FBXO9,KCTD20,RAD17,SLC17A5,SAV1,RHEB,DHX32,MFAP3L,RPL12,DNM1L,RAB11FIP2,PTER,FAM114A1,DHTKD1,MDH1,PDXK,ARPC2,PSMC1,RPS6KA3,KLF7 |
| 3.804e-02 | -3.27 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_DN | 190 | 37 | 17758 | 2588 |
GRHL2,CD63,GABRG2,DHX8,PSMD10,BLCAP,TGFBR3,ARTN,CTSC,METTL7A,RGS3,PLCG2,FBXO7,DRAM1,PLEKHF1,CRY2,GOT1,NCAM1,GFI1,PTPRE,F2R,APOBEC3G,DNAI1,ENPP4,ERMAP,MAPKAPK3,MGAM,RAB38,LDB2,GABRD,DDAH1,CD8A,JAK1,HTT,SECTM1,RAB11FIP1,FGD6 |
| 3.804e-02 | -3.27 | GSE15215_CD2_POS_VS_NEG_PDC_DN | MSigDB lists | GSE15215_CD2_POS_VS_NEG_PDC_DN | 190 | 37 | 17758 | 2588 |
TRAPPC10,UGP2,TMEM41B,ARHGEF7,TRAF2,DHX8,TEX2,CA2,PTEN,ELMO2,RANBP1,DLG1,PIK3CA,GOT1,PIKFYVE,GFI1,ITM2C,IL10RB,ERAP2,RHOA,PAPD7,CDYL,SERTAD3,NPC2,FECH,LRRC42,TMEM50B,PPP2R5A,SEMA4D,ACYP1,SLC9A6,DBI,NMI,CLMN,IRF7,RTN3,ATMIN |
| 3.804e-02 | -3.27 | GSE17721_CTRL_VS_POLYIC_24H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_24H_BMDM_UP | 190 | 37 | 17758 | 2588 |
CCDC109B,CUL4B,PDCL,ABCG2,TESK2,NUCB2,HDAC6,HTR1D,FAM111A,CCNA2,STIM1,FAM63A,AKR1B1,SCN2A,CPE,MYO5A,WBP5,POU6F1,ERMP1,KIF13A,ARHGDIB,PRKRA,ANLN,TP53INP2,DAG1,TMEM50B,NUCB1,ENPP1,FAM64A,NGFRAP1,KBTBD2,CTSA,CCNB2,CD81,RARG,MYL12B,CPPED1 |
| 3.804e-02 | -3.27 | GSE13229_IMM_VS_INTMATURE_NKCELL_DN | MSigDB lists | GSE13229_IMM_VS_INTMATURE_NKCELL_DN | 190 | 37 | 17758 | 2588 |
GCLM,ACTR8,SHPRH,CERCAM,DGKQ,AES,CAPN2,PPP1R10,ELMO2,DPYSL2,AIM1,RPN2,PDIA6,PTPRE,MYLIP,SYK,NAGA,FAM69A,MAP3K3,SIRT1,QSOX1,MARK1,ING1,SEPT6,ACBD3,PRKRA,NDRG3,GNA11,RASGRP2,CASP7,PEX5,KLF12,MTFMT,PPP2R5A,ACADM,SLC27A3,ABCA1 |
| 3.812e-02 | -3.27 | V$PAX_Q6 | MSigDB lists | V$PAX_Q6 | 238 | 45 | 17758 | 2588 |
PPP1R12A,BLVRB,ETV5,FLOT1,GATA3,RNF182,TGFBR1,PLAC1,CD274,EGR3,FAM81A,HOXB2,PRRG4,NRP2,FANCI,ICAM1,XPR1,CDK14,IER3,RNF220,SRPX,CYR61,RGS3,MEGF8,LMO4,TWIST1,RFX5,DLG3,SPRY2,DOCK4,TAF5,UNC45B,DDX23,IRX3,BTG1,TBC1D17,PTK7,ITGA7,P4HA2,SP6,NRG1,LRRK1,SEMA3A,UBE2C,FOXA1 |
| 3.812e-02 | -3.27 | positive regulation of multicellular organismal process | biological process | GO:0051240 | 1353 | 225 | 16441 | 2455 |
ACACB,ACVR1,AGRN,LGR4,EPHA4,RET,CACNA2D2,GATA3,IL18,CAMK1D,CCNB1,HDAC6,PDGFB,GRM5,TP73,CTNNB1,CTGF,NPNT,CDKL5,IL6ST,CTTN,PACSIN1,TIAM1,RASGRP1,CYP1B1,NLRP4,SOD1,ITCH,EZR,LOXL2,F12,POR,RHEB,IRX3,DPYSL3,PLCG1,GPRC5B,HPSE,AGPAT2,LIMK1,TBX1,NOD2,BMP1,MAPK13,ITPKA,HSPB1,F2RL1,DDX58,GRN,RUNX2,SERPINE2,LGALS3,HLA-E,SOX9,ETV5,PRKAA1,IL18R1,BMP2,SPP1,RB1,ITGA3,CA2,CYR61,FAM20C,GATA2,MEGF8,FLRT3,SUCO,PRKCI,TNFRSF12A,NPTN,MYDGF,NTN1,WNT3A,RIMS2,SOCS5,EPB41L5,MMD,ANO6,WHSC1,HMG20B,PDE5A,PLS1,KIF20B,EPHA1,ILK,RHOB,GNAS,MAPKAPK2,NCOA3,SEMA4D,PLPP3,CSF1,TMEM30A,NFKBIA,AURKA,IFIH1,SEMA3A,TRPC3,TMEM173,IRF1,FOXO6,HOXB7,IL15,INPP5D,P2RX7,IL27RA,OSR2,CD274,EGR3,TNFSF9,SYTL2,CCND1,CD46,PDGFA,PLCG2,BCL6,SMO,DAB2IP,TWIST1,EPB41L4B,PDE4D,TMEM64,NFKB2,F2R,TMBIM1,SULF2,ENPP4,TIMP2,RIPK2,AKT1,DMTN,CDC20,PTGER4,CLSTN1,PRKCQ,CD40,DAG1,ARHGAP35,PTGS2,FYN,ATP1A1,BHLHB9,AXL,STAT6,PTK7,WWTR1,SLC27A1,EFNA5,NRG1,IRF7,RGS14,ARNT,COBL,BIN1,WASF3,ANXA3,CTHRC1,NKX3-1,TRAF2,FLOT1,CRABP2,ETS1,SRPX2,TEAD3,ICAM1,ADGRB2,HLA-A,NRP2,SIX4,HDAC9,CTNNBIP1,CARD8,IRAK1,BMP7,TFAP2A,BAX,IL17RA,H2AFY,TRIM21,MAPK11,CITED2,RAG1,MAP3K7,IQGAP3,SYK,FAM134C,TLE6,MSH6,HES1,TGIF1,ADAM17,RHOA,WNT10B,ASPM,RAPGEF2,PIK3R1,RGCC,FOS,BCAR1,BBS2,MAP1B,BCL10,TXK,GPLD1,CD83,BTG1,DDAH1,PROM1,FGFR2,ACVRL1,TBX18,FGF18,DTX4,NR4A3,ERAP1,PPP2R3C,GPER1,SOX8,OSR1,FZD5,ARSB,SHOX2,L1CAM,FOXA1 |
| 3.816e-02 | -3.27 | GSE22886_CTRL_VS_LPS_24H_DC_UP | MSigDB lists | GSE22886_CTRL_VS_LPS_24H_DC_UP | 196 | 38 | 17758 | 2588 |
CHCHD7,ZCCHC24,NDUFA4,ISYNA1,MGST2,CDIPT,VASH1,PDIA4,C7orf49,METTL7A,ATP5H,MGAT4A,RPL39,BDH1,ADCK2,PLCB2,ALDH3A2,SYK,GCA,MLEC,TACC1,SH3BGRL,S100A4,RNF113A,ESYT1,GTF2A2,GNAS,TRAM2,STX10,GDE1,CDK19,ARHGAP4,CHPT1,NRGN,RTN3,DEF6,CTDSP1,EGLN1 |
| 3.816e-02 | -3.27 | GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN | 196 | 38 | 17758 | 2588 |
GAA,IL15RA,CDKN1C,AASS,PHLPP1,SAC3D1,TFAP4,FLII,TYMP,ANK1,CDH1,GNB5,SIVA1,MCF2L,SNED1,MCCC2,MX1,SHMT1,ZWINT,MAPKAPK3,STAT4,EZR,H2AFV,GNA11,MAPKAPK2,PEX5,CASP7,TIMP3,RBL1,SPINT2,INPP4B,TLE1,NRG1,IRF7,KPNA2,PIEZO1,TRAF5,RUSC1 |
| 3.820e-02 | -3.27 | positive regulation of mononuclear cell proliferation | biological process | GO:0032946 | 117 | 25 | 16441 | 2455 |
HES1,CD55,RIPK2,DHPS,IL15,HLA-E,IL18,PRKCQ,CD274,CD40,TNFSF9,EFNB1,HLA-A,IRS2,CD46,IL6ST,CSF1,BCL6,IGFBP2,ICOSLG,WNT3A,SLC39A10,CD81,JAK3,SYK |
| 3.821e-02 | -3.26 | NUCLEAR_REC_DBD_2 | prosite domains | PS51030 | 46 | 12 | 11866 | 1802 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 3.821e-02 | -3.26 | NUCLEAR_REC_DBD_1 | prosite domains | PS00031 | 46 | 12 | 11866 | 1802 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 3.821e-02 | -3.26 | Znf_RING_CS | interpro domains | IPR017907 | 166 | 33 | 18293 | 2672 |
RNF224,TRIM2,TRIM24,TRIM5,SHPRH,TRAF2,CBLL1,RNF182,BARD1,TRIM68,SH3RF2,DTX3L,MKRN3,TRIM3,TRIM21,RAG1,TRIM62,RNF169,PCGF5,TRIM8,LONRF3,RC3H2,TRIM35,RNF113A,CBL,TRIM7,TRIM9,TRIM47,TRIM69,PEX2,TRIM45,TRAF5,RNF146 |
| 3.826e-02 | -3.26 | V$MEF2_03 | MSigDB lists | V$MEF2_03 | 226 | 43 | 17758 | 2588 |
ELK4,SLC2A4,CPEB4,HOXB7,NDRG2,RASGRP3,FAM81A,KTN1,ART5,NFAT5,PPP2R3A,ZNF385B,HDAC9,SCML1,FOXP2,PAK6,OPN3,NEK2,AKR1B1,TWIST1,PHKA2,ARMCX6,CRTAP,C9orf9,TRAK2,RASGRF1,SMARCA2,CASK,TIMP2,NR4A1,TEF,RGAG1,STRADB,FOS,ZFAND5,NFIB,RHOB,NEIL3,ITGA7,AMMECR1,RAP2C,MYLK,SIPA1L1 |
| 3.826e-02 | -3.26 | V$AP2ALPHA_01 | MSigDB lists | V$AP2ALPHA_01 | 226 | 43 | 17758 | 2588 |
CCDC24,IER5L,SCN5A,GRHL2,CERCAM,THRA,SOX9,PKN1,PDGFB,DDR1,TSPAN17,NFAT5,TFAP4,APLP2,RNF220,ARTN,ZNRF2,ATP5H,LMO4,LHX6,TRPC1,NOTCH3,ETV4,DGKG,CXXC5,NR3C1,CBX6,RGAG1,MAP3K6,NFIB,SP4,MAP1B,CD83,PITX2,KLF12,DGCR2,MAP3K11,NXPH4,RARG,JARID2,IRF1,DMPK,NR2C2 |
| 3.827e-02 | -3.26 | SYVN1 (synovial apoptosis inhibitor 1, synoviolin) | protein interactions | 84447 | 79 | 19 | 16036 | 2547 |
ERLEC1,PSMB4,AMFR,TP53,PSMD7,UBE2Z,POR,HLA-A,VCP,NAAA,PSMD1,HTT,WFS1,UBE2D2,UBE2J1,SARAF,SGK1,YOD1,PSMA5 |
| 3.828e-02 | -3.26 | protein maturation | biological process | GO:0051604 | 274 | 52 | 16441 | 2455 |
CASP3,NKX3-1,TSPAN15,DAP,TRAF2,RHBDL3,RET,P2RX7,CTSZ,AIP,ATG4A,CAPN2,CALR,CARD8,CTSC,BAX,CDKN1B,SORL1,ECE1,EGLN3,LGMN,F2R,CPE,TSPAN33,METAP2,ATG4D,CPD,ADAMTS2,PMPCB,CASP9,ERO1A,FURIN,KLK6,SLC11A2,F12,BCL2L13,CYFIP2,TYSND1,VCP,NMT2,FAS,ZMPSTE24,PRDX4,CASP7,IDE,NGFRAP1,WFS1,CTSV,SPCS3,CAPN1,XDH,PCSK5 |
| 3.836e-02 | -3.26 | IMMT (inner membrane protein, mitochondrial) | protein interactions | 10989 | 105 | 24 | 16036 | 2547 |
MRPL44,PINK1,ARMCX3,HJURP,LGR4,SLC25A13,SUZ12,CALM1,TXNDC9,FBXO6,SMN1,EGFR,SGPL1,IRAK1,NIPSNAP3A,PLA2G15,TRAF3IP1,NEK2,CSTF2,KPNA2,KIF22,LRIF1,CD81,HP1BP3 |
| 3.839e-02 | -3.26 | Mitochondrial_sb/sol_carrier | interpro domains | IPR018108 | 53 | 13 | 18293 | 2672 |
SLC25A48,SLC25A45,SLC25A24,SLC25A4,SLC25A13,SLC25A40,SLC25A27,SLC25A38,SLC25A30,SLC25A43,SLC25A5,SLC25A35,SLC25A36 |
| 3.839e-02 | -3.26 | Mt_carrier_dom | interpro domains | IPR023395 | 53 | 13 | 18293 | 2672 |
SLC25A48,SLC25A45,SLC25A24,SLC25A4,SLC25A13,SLC25A40,SLC25A27,SLC25A38,SLC25A30,SLC25A43,SLC25A5,SLC25A35,SLC25A36 |
| 3.848e-02 | -3.26 | mTOR signaling pathway | KEGG pathways | hsa04150 | 60 | 15 | 6908 | 1076 |
PRKAA2,TSC1,RPS6KA2,AKT1,PTEN,RPS6KA1,PIK3R1,PRKAA1,PIK3CA,CAB39,PIK3CD,RHEB,ULK2,RPS6KA3,RRAGD |
| 3.848e-02 | -3.26 | mTOR signaling pathway | KEGG pathways | ko04150 | 60 | 15 | 6908 | 1076 |
PRKAA2,TSC1,RPS6KA2,AKT1,PTEN,RPS6KA1,PIK3R1,PRKAA1,PIK3CA,CAB39,PIK3CD,RHEB,ULK2,RPS6KA3,RRAGD |
| 3.850e-02 | -3.26 | ZBTB7A (zinc finger and BTB domain containing 7A) | protein interactions | 51341 | 30 | 9 | 16036 | 2547 |
TFAP4,SIRT1,RB1,NFKBIA,SOX9,TP53,BCL6,HDAC1,SP4 |
| 3.850e-02 | -3.26 | MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1) | protein interactions | 9479 | 30 | 9 | 16036 | 2547 |
ARHGEF28,AKT1,MAP3K11,ERBB2,MAP3K7,TIAM1,EGFR,MAPK8IP1,SOCS3 |
| 3.850e-02 | -3.26 | PTGS2 (prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)) | protein interactions | 5743 | 30 | 9 | 16036 | 2547 |
PTGS2,NUCB1,PSMD1,CASK,CTNNB1,ZFP36,TP53,CUL1,VCP |
| 3.850e-02 | -3.26 | Mbp (myelin basic protein) | protein interactions | 17196 | 30 | 9 | 16036 | 2547 |
FYN,ARHGEF7,CALM1,MPP2,YES1,CTTN,MAP3K5,NEB,RASA1 |
| 3.850e-02 | -3.26 | MAP1A (microtubule associated protein 1A) | protein interactions | 4130 | 30 | 9 | 16036 | 2547 |
SPP1,PRKAG2,ARHGEF11,GGA1,TRAF3IP1,DLG1,MAP1LC3B,MAP1B,TUBA4A |
| 3.850e-02 | -3.26 | IL2RB (interleukin 2 receptor, beta) | protein interactions | 3560 | 30 | 9 | 16036 | 2547 |
FYN,JAK1,IL15RA,IL15,PIK3R1,STAT1,JAK3,SYK,SOCS3 |
| 3.850e-02 | -3.26 | FEM1B (fem-1 homolog b (C. elegans)) | protein interactions | 10116 | 30 | 9 | 16036 | 2547 |
EPN3,NKX3-1,TCEB2,KIAA0319,DCUN1D1,DMWD,MVB12B,WNT3A,FAS |
| 3.853e-02 | -3.26 | ANTIPRLFBTG1 | prints domains | PR00310 | 6 | 3 | 4759 | 661 |
BTG3,BTG1,TOB1 |
| 3.853e-02 | -3.26 | INTRLKN1R12F | prints domains | PR01536 | 6 | 3 | 4759 | 661 |
IL1R1,IL1RAP,IL18R1 |
| 3.853e-02 | -3.26 | ACOABINDINGP | prints domains | PR00689 | 6 | 3 | 4759 | 661 |
ACBD5,ECI2,DBI |
| 3.854e-02 | -3.26 | oxidoreductase activity | molecular function | GO:0016491 | 712 | 123 | 16491 | 2452 |
CFAP61,TXN,NQO1,AASS,CRYM,P3H2,SOD2,PDIA5,GMPR,FTH1,MGST2,AIFM2,CYP39A1,CYP26A1,ASPHD2,CYP1A1,CYP4F11,P4HB,CYP2S1,ALDH1A3,RDH14,AOX1,STEAP2,AKR1B1,VAT1,STEAP3,ACOX2,TECR,ETHE1,EGLN3,LOXL1,FAR1,GPX4,CYP1B1,SOD1,AGPS,CYB5R2,COX11,HTATIP2,LOXL2,AKR1E2,MRPS36,IDH1,TP53I3,POR,PDHX,CYP4F3,KDM4D,KDSR,DNAJC10,PTGS2,ALDH3B1,DUOX1,ALDH5A1,DHRS13,UEVLD,ACAD10,P4HA2,DHTKD1,MAOA,CYP2U1,C1orf43,AIFM3,PDPR,DLAT,FAM213B,ALDH6A1,CYP2J2,PYROXD2,SCD5,BLVRB,ADO,OSGIN2,PDIA3,CYB561,NDUFA4,COX6C,SPR,DHRS3,QSOX2,LBR,RSAD1,COX7A2,BMP2,BDH1,FDXR,PCYOX1,ALDH7A1,ACAD8,MOXD1,FAR2,NDUFA12,ALDH3A2,TMX1,OSGIN1,CYP26B1,QSOX1,FADS2,PRODH,ALDH2,OXR1,ERO1A,OGDHL,BLVRA,KDM3A,STEAP1,CYB5A,PRDX4,DHDH,MARC1,FA2H,ACADSB,PLOD2,PRDX3,DHRS2,P4HA3,MDH1,ACADM,PLOD3,CTBP1,CYBRD1,XDH,EGLN1 |
| 3.854e-02 | -3.26 | Endocytosis | KEGG pathways | hsa04144 | 258 | 51 | 6908 | 1076 |
BIN1,ARAP3,HLA-F,HLA-E,RET,ARFGEF1,TGFBR1,PLD2,GRK6,MVB12B,FAM21C,VPS26A,SH3KBP1,HLA-A,ZFYVE9,KIF5B,ZFYVE16,ACAP2,ADRBK1,IGF1R,PRKCI,DNM2,WWP1,HLA-C,ERBB3,F2R,HSPA2,RHOA,ARAP2,ITCH,VPS4B,CBL,SNX12,ADRBK2,EGFR,EPN3,HLA-B,LDLRAP1,RAB11FIP2,FGFR2,RAB31,ARAP1,RAB11FIP1,SH3GLB2,ARRB1,ARFGAP3,CHMP4B,PLD1,ARF6,ARPC2,EHD1 |
| 3.854e-02 | -3.26 | Endocytosis | KEGG pathways | ko04144 | 258 | 51 | 6908 | 1076 |
BIN1,ARAP3,HLA-F,HLA-E,RET,ARFGEF1,TGFBR1,PLD2,GRK6,MVB12B,FAM21C,VPS26A,SH3KBP1,HLA-A,ZFYVE9,KIF5B,ZFYVE16,ACAP2,ADRBK1,IGF1R,PRKCI,DNM2,WWP1,HLA-C,ERBB3,F2R,HSPA2,RHOA,ARAP2,ITCH,VPS4B,CBL,SNX12,ADRBK2,EGFR,EPN3,HLA-B,LDLRAP1,RAB11FIP2,FGFR2,RAB31,ARAP1,RAB11FIP1,SH3GLB2,ARRB1,ARFGAP3,CHMP4B,PLD1,ARF6,ARPC2,EHD1 |
| 3.854e-02 | -3.26 | leukocyte differentiation | biological process | GO:0002521 | 298 | 56 | 16441 | 2455 |
RUNX2,IL15,LFNG,TP53,GATA3,JAG2,NOTCH2,MERTK,FLT3,IL18R1,TNFSF9,HDAC9,CD109,CTNNB1,FAM20C,GATA2,GPC3,PLCG2,MITF,IL31RA,BAX,BCL6,MSH2,FNIP1,PIK3CD,RAG1,SNX10,SYK,FARP2,ADAM17,RHOA,LGALS8,OSTM1,PIK3R1,RC3H2,PTGER4,CR2,GLO1,EIF2AK1,FZD7,CMTM7,TXK,FAS,CD8A,TSC1,ONECUT1,DHRS2,STAT6,AXL,CSF1,LRRK1,FZD5,RPL22,JAK3,F2RL1,IRF1 |
| 3.857e-02 | -3.26 | brain development | biological process | GO:0007420 | 653 | 114 | 16441 | 2455 |
EMX1,CASP3,GRHL2,NF2,HSPG2,AK7,THRA,CAST,SUDS3,TP53,NDRG2,SEPT4,STIL,PHLDA1,SDF4,CALM2,TP73,TTC21B,APLP2,CTNNB1,CDH1,TACC2,DPYSL2,KIF14,LHX6,ALDH1A3,SRR,SMO,DAB2IP,DIXDC1,ARNT2,NOTCH3,ZBTB18,BTBD3,SPEF2,MBP,CELSR2,FZD4,TFAP2C,ARF4,ABR,NFIX,ARHGAP35,IRS2,MDK,FYN,PAFAH1B3,AXL,NRG1,NRGN,ANXA3,SCN5A,CDH22,SERPINE2,ADGRG1,NES,CALM3,CNTNAP2,SEPP1,ETS1,HOXB2,PGAP1,FZD6,GBX2,MECOM,FOXP2,BMP2,IGF1R,OXCT1,PTEN,GATA2,KNDC1,CST3,PRKG1,BAX,CD9,WNT3A,POU6F1,HES1,RHOA,TACC1,ASPM,RAPGEF2,CALM1,SHARPIN,GRIN1,AK4,TCF7,SCRIB,BBS2,NFIB,CDK5R1,EGFR,FAS,CDK5RAP1,PITX2,TSC1,CTNS,FAT4,HTT,FGFR2,TWSG1,PHLPP2,DBI,E2F1,RYK,NR4A3,PCDH19,NR4A2,NDE1,WDR62,SHROOM2,SEMA3A,DRD1 |
| 3.858e-02 | -3.26 | regulation of proteolysis | biological process | GO:0030162 | 759 | 131 | 16441 | 2455 |
CASP3,RET,XIAP,CUL1,PSME1,CCNB1,HDAC6,SNX9,PSMD1,RPS6KA2,CTGF,PSMC2,PLK1,CD55,ACVR1C,ITCH,PBK,USP18,CASP9,F12,RNF19B,CDK1,POR,VCP,PLK2,SERPINB6,SERPINI1,PSMC1,SERPINE2,DNAJB2,RAB23,PSMD7,FBLN1,TFAP4,RB1,TIMP1,CYR61,PAK2,DAPK1,FNIP1,SORL1,USP38,USP1,WNT3A,PSMA5,SOCS5,USP31,MFI2,BCL2L13,CYFIP2,PSMA4,FAS,HTT,AURKA,MAP3K5,SERPINB1,IFI6,RPS6KA3,XDH,USP43,DLGAP5,PSME2,CAST,RPS6KA1,PTTG1,TP53,PRKACA,BCAP31,RAD23A,CD46,APLP2,CDKN1B,DAB2IP,EGLN3,OSBPL7,F2R,CDKN2D,SIRT1,TIMP2,AKT1,CDC20,SLC11A2,SNX12,IDE,NGFRAP1,PSMD3,MAPK12,NKX3-1,PCOLCE,PINK1,TRAF2,SH3D19,DAP,SERPINB9,PSMD10,TRIB2,CD109,CARD8,PTEN,CTSC,GPC3,CST3,BAX,TRIM21,BUB1,RAG1,RHOA,WNT10B,PSMB4,GCLC,PLAUR,NUB1,FURIN,PRICKLE1,COL7A1,GPLD1,USP6,BCL10,TIMP3,CASP7,KIAA0141,SERPINA1,PRDX3,SPINT2,ARRB1,SERPINB5,CENPE,GPER1,UBE2C,ESPL1,USP16 |
| 3.868e-02 | -3.25 | AUP1 (ancient ubiquitous protein 1) | protein interactions | 550 | 49 | 13 | 16036 | 2547 |
FAF2,DDOST,AMFR,RNF11,UBE2J1,RPN2,ITGAV,FBXO6,STT3B,ILK,ITGA2B,VCP,CKAP5 |
| 3.870e-02 | -3.25 | phosphatidylcholine biosynthetic process | biological process | GO:0006656 | 27 | 8 | 16441 | 2455 |
SLC44A1,PHOSPHO1,SLC44A2,SLC27A1,LPIN3,CHPT1,SLC44A3,CDS1 |
| 3.870e-02 | -3.25 | regulation of anion transmembrane transport | biological process | GO:1903959 | 27 | 8 | 16441 | 2455 |
IRS2,TCAF1,CLCN3,AKT1,ANO6,ANO9,CLCN2,ANO1 |
| 3.870e-02 | -3.25 | homeostasis of number of cells within a tissue | biological process | GO:0048873 | 27 | 8 | 16441 | 2455 |
ADD1,GATA2,CSF1,SOX9,SMO,BAX,P2RX7,F2R |
| 3.870e-02 | -3.25 | prostate gland morphogenesis | biological process | GO:0060512 | 27 | 8 | 16441 | 2455 |
NKX3-1,IGF1R,FGFR2,SOX9,SERPINB5,HOXB13,RARG,FOXA1 |
| 3.870e-02 | -3.25 | regulation of mesonephros development | biological process | GO:0061217 | 27 | 8 | 16441 | 2455 |
HOXB7,LGR4,SOX9,SMO,GATA3,TACSTD2,SOX8,SIX4 |
| 3.870e-02 | -3.25 | regulation of fibroblast growth factor receptor signaling pathway | biological process | GO:0040036 | 27 | 8 | 16441 | 2455 |
RUNX2,CTNNB1,FGFR2,FAM20C,GATA3,NPTN,SPRY2,SULF2 |
| 3.877e-02 | -3.25 | MAPKPHPHTASE | prints domains | PR01764 | 10 | 4 | 4759 | 661 |
DUSP10,DUSP4,DUSP5,DUSP1 |
| 3.889e-02 | -3.25 | motor activity | molecular function | GO:0003774 | 129 | 27 | 16491 | 2452 |
MYO5B,DYNLRB1,KIF3C,KIFC2,KIF20A,KLC2,KIF23,KIF1C,KIF20B,KIF13A,KIF2C,KIF26A,KIF11,DNAH3,APPBP2,MYO5C,KIF5B,DNAH6,KIF13B,KIF14,KLC3,KIF22,MYH14,CENPE,KIF12,MYO5A,DNAI1 |
| 3.892e-02 | -3.25 | endochondral bone morphogenesis | biological process | GO:0060350 | 52 | 13 | 16441 | 2455 |
GNAS,INPPL1,RUNX2,HSPG2,COL13A1,IMPAD1,NAB2,SOX9,FGF18,CSGALNACT1,PHOSPHO1,SHOX2,RARG |
| 3.895e-02 | -3.25 | ETS_DOMAIN_1 | prosite domains | PS00345 | 22 | 7 | 11866 | 1802 |
ELK4,ELK3,ETS2,ELK1,ETS1,ETV4,ETV5 |
| 3.895e-02 | -3.25 | GUANYLATE_KINASE_2 | prosite domains | PS50052 | 22 | 7 | 11866 | 1802 |
MPP5,CASK,TJP3,DLG3,MPP1,DLG1,MPP2 |
| 3.895e-02 | -3.25 | RASGEF_NTER | prosite domains | PS50212 | 22 | 7 | 11866 | 1802 |
RASGRF1,RASGRP3,RASGEF1A,RAPGEF2,KNDC1,RASGRP1,RASGRP2 |
| 3.898e-02 | -3.24 | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | MSigDB lists | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | 120 | 25 | 17758 | 2588 |
PSMB4,TCEB2,PSME2,PSMD7,PSMD10,PSME1,SLC25A5,PSMA4,PSIP1,HLA-A,FYN,NUP210,PSMD1,AP1M2,SLC25A4,PSMD3,RANBP1,PSMC2,PAK2,HMGA1,NUP37,PSMC1,NUP85,APOBEC3G,PSMA5 |
| 3.903e-02 | -3.24 | negative regulation of viral life cycle | biological process | GO:1903901 | 84 | 19 | 16441 | 2455 |
MX1,TRIM8,PLSCR1,TNIP1,APOBEC3D,IFITM3,TRIM5,APOBEC3H,TRIM35,TFAP4,FAM111A,SP100,TRIM21,HDAC1,RNASEL,OAS3,IFIT1,APOBEC3G,TRIM62 |
| 3.903e-02 | -3.24 | positive regulation of phospholipase activity | biological process | GO:0010518 | 84 | 19 | 16441 | 2455 |
CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,ARF4,EGFR,EDNRA,TXK,CALM2,PLCG1,ADRBK1,CYR61,FGFR2,ARL1,ITPR1,PLCB2,PRKAR1A |
| 3.903e-02 | -3.24 | nucleoside diphosphate metabolic process | biological process | GO:0009132 | 84 | 19 | 16441 | 2455 |
PGM1,CASK,ENO2,AK7,PFKFB2,MPP1,OGDHL,AK4,PKM,NUDT16,ENTPD4,PFKL,DLG1,MPP2,DHTKD1,AK3,DLG3,CMPK2,PPP2R5D |
| 3.911e-02 | -3.24 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | 86 | 19 | 17758 | 2588 |
CYP2J2,SNTB2,CYB5R2,PTGER4,IL17RB,GALNT3,APLP2,CA2,CDH1,LYPD6,ISM1,MYLK,ELF5,MAOA,ACTA2,SORL1,HOOK1,CHPT1,NR3C2 |
| 3.911e-02 | -3.24 | KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION | MSigDB lists | KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION | 86 | 19 | 17758 | 2588 |
CCNC,GCLC,CTDSPL,HEXB,PTGER4,RAB6A,SLC1A3,NRP2,CCND1,CCNA2,RBL1,PPME1,ENPP5,DLG1,AHCY,SERPINB6,IL10RB,RPS6KA3,FAM69A |
| 3.916e-02 | -3.24 | embryonic skeletal system morphogenesis | biological process | GO:0048704 | 95 | 21 | 16441 | 2455 |
SPEF2,RUNX2,GRHL2,HSPG2,HOXB7,TGFBR1,OSR2,HOXB2,SIX4,GNAS,CTNNB1,FGFR2,TBX1,MEGF8,BMP7,DLG1,TFAP2A,TWIST1,OSR1,SHOX2,MDFI |
| 3.916e-02 | -3.24 | monocarboxylic acid catabolic process | biological process | GO:0072329 | 95 | 21 | 16441 | 2455 |
CYP26B1,PCCB,PRODH,CPT2,LPIN3,ECI1,CYP4F3,CYP39A1,CYP26A1,ALDH5A1,ACADSB,FAAH,ACAD10,PEX2,PLA2G15,ECI2,ABCD1,ACADM,ACOX2,ACAD8,ACOT7 |
| 3.917e-02 | -3.24 | GNAS (GNAS complex locus) | protein interactions | 2778 | 69 | 17 | 16036 | 2547 |
ARMCX3,CPT2,CALM1,GNAL,NUCB2,GNB2,GNA11,HLA-A,EGFR,OPTN,MAGED2,GNAS,NUCB1,SNX13,ADORA1,JAK3,METAP2 |
| 3.922e-02 | -3.24 | RUNX2 (runt-related transcription factor 2) | protein interactions | 860 | 54 | 14 | 16036 | 2547 |
RB1,HES1,SOX9,TP53,FHL2,TLE1,HDAC1,WWP1,HDAC6,CCNB1,FOS,ETS1,CDK1,DVL2 |
| 3.922e-02 | -3.24 | ARF6 (ADP-ribosylation factor 6) | protein interactions | 382 | 54 | 14 | 16036 | 2547 |
DHPS,GGA1,IQGAP1,EZR,FBXO8,ARRB1,KIF23,TGOLN2,MPP5,PLD1,CAPN1,EGFR,VCP,USP6 |
| 3.922e-02 | -3.24 | STK26 (serine/threonine protein kinase 26) | protein interactions | 51765 | 54 | 14 | 16036 | 2547 |
MOB4,CAPN2,MBP,RPL12,PDCD10,STK26,STRIP2,PPP2R4,STRN4,CAPNS1,ISOC1,FGFR1OP2,EGFR,PDIA4 |
| 3.925e-02 | -3.24 | MODULE_205 | MSigDB lists | MODULE_205 | 281 | 52 | 17758 | 2588 |
KIAA1462,ZNF395,DLGAP5,HJURP,ST14,FLYWCH2,FAM129B,ITGA6,ARMC7,CACNA2D2,TP53,INTS8,GPSM2,B4GALT4,DNER,TMPRSS4,ASPHD2,CD109,NAPG,MDM1,CCNA2,MUC16,DNAH6,KIF14,FDXR,NEK2,ABCA2,DIXDC1,APIP,EGLN3,MYRIP,ULBP2,ATG4D,DPYSL5,HPS3,CITED4,SPA17,XRCC6BP1,CDC25C,SEC14L2,CACHD1,WDR11,TWSG1,FAM114A1,SERPINI1,TANC2,TMEM159,CEP41,TRAF5,E2F8,PDPR,RRAGD |
| 3.927e-02 | -3.24 | DAUER_STAT3_TARGETS_UP | MSigDB lists | DAUER_STAT3_TARGETS_UP | 48 | 12 | 17758 | 2588 |
ZFP36,CTSB,SOD2,BCL6,KLF11,EFNA1,PLIN3,MAFF,DUSP5,ABCA1,ICAM1,SOCS3 |
| 3.927e-02 | -3.24 | BILBAN_B_CLL_LPL_DN | MSigDB lists | BILBAN_B_CLL_LPL_DN | 48 | 12 | 17758 | 2588 |
FYN,MSL1,ACAP2,PNISR,SAT1,SORL1,TCF7,CCNL1,CNTNAP2,FOS,IER3,DUSP1 |
| 3.927e-02 | -3.24 | TAVOR_CEBPA_TARGETS_UP | MSigDB lists | TAVOR_CEBPA_TARGETS_UP | 48 | 12 | 17758 | 2588 |
BTG1,SERTAD2,CA2,SPINT2,SECTM1,BIK,SOD2,LITAF,RAB31,KLF5,GGH,SERPINI1 |
| 3.927e-02 | -3.24 | MODULE_285 | MSigDB lists | MODULE_285 | 48 | 12 | 17758 | 2588 |
LAMP1,TSC1,SHMT1,ZNF75D,CTNS,GCAT,TSC22D3,OSGIN2,ZBTB6,ZMYM1,DHRS3,CPPED1 |
| 3.927e-02 | -3.24 | MORF_UBE2A | MSigDB lists | MORF_UBE2A | 48 | 12 | 17758 | 2588 |
UFD1L,LASP1,DNPEP,PDCD10,CUL4B,UBE2A,PSMD10,NUBP1,MYL12B,RASA1,FAM134C,PRKAR1A |
| 3.927e-02 | -3.24 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | MSigDB lists | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | 48 | 12 | 17758 | 2588 |
PSMD1,PSMB4,NQO1,PSME2,PSMD3,PSMC2,PSMD7,PSMD10,PSME1,PSMC1,PSMA4,PSMA5 |
| 3.928e-02 | -3.24 | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 677 | 115 | 17775 | 2585 |
ILDR1,FOXM1,RALBP1,RET,NDC80,TP53,COL18A1,GRK6,AIFM2,DENND2D,TNFSF9,ART5,EPS8L2,SDF4,SYTL2,APLP2,RBM23,TRANK1,P4HB,STIM1,ZFP36,PRICKLE3,POLL,PIK3CA,FUT1,CNNM4,TMEM64,EGLN3,OSBPL7,NEB,DVL2,CCDC74A,SNX8,CLCN3,MARK1,FIGNL1,COX11,TNS1,EAF2,SAV1,COL12A1,PLCH1,TBC1D17,PTPRJ,DDOST,ANKRD6,WIPI1,ATP7B,MYLK,WWTR1,PLEKHG1,PRKCDBP,ARRDC1,SPTBN5,POMT1,ZMAT1,SCN5A,CDS2,PPP1R2,LRRFIP2,FAM169A,QSOX2,CKAP5,CES2,ALPP,LLGL2,FRAS1,KIF13B,CENPJ,TMEM62,BMP7,MEGF8,RRBP1,BDH1,PRKG1,MAP3K9,FAM102A,H2AFY,TRIM3,SLAIN2,FAR2,ZMYM1,TPCN1,CCDC88A,MYO5A,GPR161,DNAI1,PARP9,EPB41L5,SUN2,MFI2,NR4A1,PPARA,GYLTL1B,TRIM35,YES1,RNPEP,NFIB,MUM1L1,NT5C2,HTT,ACVRL1,NR1D2,ITPR1,NLRC5,RHOBTB2,FHL1,ZDBF2,PLOD3,WDR62,ESPL1,EHD1,SNPH,FBXW5,PKD1L2 |
| 3.940e-02 | -3.23 | TRIM21 (tripartite motif containing 21) | protein interactions | 6737 | 64 | 16 | 16036 | 2547 |
TRIM8,TRIM5,CUL1,AGO4,ROR1,FBXO6,CBL,DCP2,VCP,NCOA3,UBE2D2,CDKN1B,HDAC1,TRIM21,IRF7,UBE2C |
| 3.940e-02 | -3.23 | NRIP1 (nuclear receptor interacting protein 1) | protein interactions | 8204 | 64 | 16 | 16036 | 2547 |
THRB,CEP70,NR3C1,THRA,TRAF2,PPARA,HDAC9,E2F1,HDAC1,FHL1,MAP3K7,NR2C1,CTBP1,AHR,NR3C2,FOXA1 |
| 3.944e-02 | -3.23 | HTRA2 (HtrA serine peptidase 2) | protein interactions | 27429 | 59 | 15 | 16036 | 2547 |
RMND5A,PINK1,TRAF2,DSTN,XIAP,VPS4B,NADK2,MAPK11,GOT1,MAPK13,CD40,AREL1,CDK1,PDXDC1,MAPK12 |
| 3.944e-02 | -3.23 | TRAF5 (TNF receptor-associated factor 5) | protein interactions | 7188 | 59 | 15 | 16036 | 2547 |
DGKH,TRIM8,RIPK2,NGFRAP1,TRAF2,NMI,SERPINB9,TNFRSF12A,CAPNS1,MAP3K7,MAP3K5,CD40,TRAF5,TNFRSF19,RAD23A |
| 3.944e-02 | -3.23 | CBLB (Cbl proto-oncogene B, E3 ubiquitin protein ligase) | protein interactions | 868 | 59 | 15 | 16036 | 2547 |
FYN,UBASH3B,ARHGEF7,PLCG2,RET,RNF11,PIK3R1,UBE2D2,SORBS3,CBL,FLT3,SPRY2,SYK,SH3KBP1,EGFR |
| 3.951e-02 | -3.23 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | 103 | 22 | 17758 | 2588 |
ANXA3,LZTFL1,PPP4R4,NUAK1,STAT4,GATA3,LOXL2,DOCK11,MEST,DHRS3,FBLN1,NFIB,SYTL2,FZD7,PRKAG2,GPRC5B,PLOD2,PRKCI,TLE1,LTBP2,EPB41L4B,HSPA2 |
| 3.953e-02 | -3.23 | KEGG_VEGF_SIGNALING_PATHWAY | MSigDB lists | KEGG_VEGF_SIGNALING_PATHWAY | 75 | 17 | 17758 | 2588 |
PLA2G4A,AKT1,MAPKAPK3,CASP9,PIK3R1,NFAT5,MAPKAPK2,PLCG1,RAC2,PTGS2,PLCG2,PIK3CA,MAPK13,MAPK11,PIK3CD,HSPB1,MAPK12 |
| 3.962e-02 | -3.23 | Golgi-associated vesicle | cellular component | GO:0005798 | 80 | 18 | 17570 | 2579 |
SORT1,SLC2A4,BACE1,FURIN,TGOLN2,C3orf58,NUCB1,LDLRAP1,STK26,OCRL,STEAP2,ZDHHC13,PACSIN1,RAB27B,NRGN,COPG1,TMED2,KDELR1 |
| 3.967e-02 | -3.23 | SMAD2 (SMAD family member 2) | protein interactions | 4087 | 281 | 56 | 16036 | 2547 |
UNKL,RUNX2,ST13,TBC1D1,DCAF7,SOX9,TP53,DGKA,DHX8,TGFBR1,ZFYVE9,C1orf116,MECOM,WWP2,TP73,ST5,CTNNB1,PIK3CA,WWP1,ARL4D,CITED2,ETV4,TRIM62,CAMK2G,EPB41L5,TGIF1,SOD1,RHOA,DCAF6,AKT1,ITCH,S100A4,PARD3B,FHL2,RGCC,LITAF,RUNX3,ERBB2IP,RAB38,SLC25A5,RANBP9,PIAS3,NCOA3,INSR,RBL1,HOXA9,DCUN1D1,HDAC1,ARFGAP3,KLF5,IRF7,FHL1,PLIN3,TOB1,PRKAR1A,DOCK9 |
| 3.976e-02 | -3.22 | AAGCCAT,MIR-135A,MIR-135B | MSigDB lists | AAGCCAT,MIR-135A,MIR-135B | 318 | 58 | 17758 | 2588 |
KCNAB3,FRMD4A,RALBP1,ARHGEF7,BACE1,ADO,MIER3,GATA3,C6orf106,C1orf198,PHOSPHO1,KCTD12,TRAPPC8,TGFBR1,MRAS,HERC6,DUSP5,PSIP1,ZNF385B,B4GALNT1,SNTA1,ENTPD4,FAM46A,IL6ST,SLC44A1,TRPC1,CPLX1,ALPK1,CACNA1D,ANO4,TMEM9,RIMS2,STK35,CPD,THRB,SIRT1,GCC2,ELK3,FBXL16,ATP1B1,ELK1,SLC25A5,DAG1,LCP1,DGKH,MYPOP,CNTNAP1,PLCG1,SERTAD2,STAT6,PELI2,PHLPP2,PTER,CSNK1G1,CHMP4B,NR3C2,LZTS1,ARHGEF4 |
| 3.979e-02 | -3.22 | MGGAAGTG_V$GABP_B | MSigDB lists | MGGAAGTG_V$GABP_B | 727 | 123 | 17758 | 2588 |
ELK4,PAX6,CPT2,NDRG1,CAST,DGKA,DHX8,BCL2L1,ITPR2,MORF4L2,COMMD5,DPP8,PRKACA,CMTM6,PICK1,CHPF,PER2,C11orf84,ZFYVE16,RALB,SHC3,RGS3,PPME1,MKRN3,MITF,POLL,SERINC2,SNX16,TWIST1,ACSL4,TAF5,BAG4,MARK1,NRBF2,UXT,LYRM1,PPP1R14C,ITPR3,GTF2A2,CLCN2,RAB2B,LCP1,DPYSL3,DDOST,WIPI1,CORO1C,PEX2,GLA,ARHGAP4,RGS14,GEN1,STARD13,MAD2L1BP,CTDSP1,FGD1,CMAS,BMF,CPEB4,GGA1,SLC41A1,ARHGEF7,ZCCHC24,ETV5,PDIA3,TRMT2B,PKN1,DUSP5,BMP2K,DNAJB9,TEAD3,KIF5B,IRF2BPL,VASP,IGF1R,CES2,PPP1R10,RINL,TMEM62,MGAT4A,FAM13B,RANBP1,FCHO1,FAM63A,BAX,FXYD5,CKS1B,OSTF1,CACNA1D,NCAM1,CITED2,GFI1,PLCB2,SPRY2,RBMS2,TMX1,DNAI1,PIGC,UFD1L,ELK3,MLEC,CRB3,DEPDC4,PHLDB3,FURIN,FBXO8,TCF7,MAGED2,DCAF10,FUCA1,FNTA,PRKAG2,HNRNPH2,SLC35B3,RAP2C,ARAP1,APPL2,CLMN,AURKA,ALPK3,NR4A2,HMGA1,RPS6KA3,SRSF9 |
| 3.982e-02 | -3.22 | endothelial cell development | biological process | GO:0001885 | 47 | 12 | 16441 | 2455 |
CTNNB1,RAPGEF2,RAP2C,CCM2,EZR,COL18A1,F11R,PDE4D,PLOD3,F2RL1,ARHGEF26,ICAM1 |
| 3.982e-02 | -3.22 | cardiac septum morphogenesis | biological process | GO:0060411 | 47 | 12 | 16441 | 2455 |
HES1,ACVR1,CYR61,FGFR2,TBX1,SMO,WHSC1,NOTCH2,CITED2,SAV1,DHRS3,EGLN1 |
| 3.988e-02 | -3.22 | Nucl_hrmn_rcpt_lig-bd | interpro domains | IPR000536 | 48 | 12 | 18293 | 2672 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 3.989e-02 | -3.22 | skin-face-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-face-other-atypical_Spitzoid_tumour | 23 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.989e-02 | -3.22 | skin-upper_leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-upper_leg-other-atypical_Spitzoid_tumour | 23 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.989e-02 | -3.22 | skin-scalp-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-scalp-benign_melanocytic_nevus-Spitz | 23 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.989e-02 | -3.22 | skin-arm-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-arm-other-atypical_Spitzoid_tumour | 23 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.989e-02 | -3.22 | skin-lower_leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-lower_leg-other-atypical_Spitzoid_tumour | 23 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.989e-02 | -3.22 | atypical_Spitzoid_tumour | COSMIC cancer mutations | atypical_Spitzoid_tumour | 23 | 7 | 17775 | 2585 |
KIF5B,CEP89,GNA11,LMNA,MYO5A,HLA-A,TP53 |
| 3.989e-02 | -3.22 | ovary-carcinoma-mixed_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mixed_carcinoma | 23 | 7 | 17775 | 2585 |
CTNNB1,IDH1,FGFR2,PTEN,MSH2,PIK3CA,TP53 |
| 3.992e-02 | -3.22 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular function | GO:0000982 | 324 | 60 | 16491 | 2452 |
RUNX2,EPAS1,SOX9,TP53,GATA3,ZNF219,NFAT5,SIX4,MXD1,TFAP2E,ELF3,TP73,TFAP4,GRHL1,GATA2,BHLHE41,MITF,FOSB,EBF4,TFAP2A,ARNT2,NFKB2,GFI1,DLX4,MYBL1,ETV4,NR2C1,NFE2L3,HES1,TGIF1,ELK3,KCNIP3,PLSCR1,NR3C1,FOXJ2,NR4A1,PPARA,MYBL2,TFAP2C,ELK1,FOS,NFIB,EBF2,TXK,PITX2,MYPOP,NCOA3,ONECUT1,ETS2,PRDM5,NR4A3,OVOL1,KLF5,NR4A2,IRF7,AKNA,E2F8,HOXC13,FOXA1,IRF1 |
| 3.994e-02 | -3.22 | cilium | cellular component | GO:0005929 | 464 | 82 | 17570 | 2579 |
CFAP74,DYNLRB1,KIF3C,TCTN2,KLC2,C5orf30,SEPT4,PRKACA,MAP1LC3B,MNS1,TTC21B,INPP5E,RAB15,ANKS6,SCNN1A,LRRC6,DNAH6,IQCE,SMO,TUBG1,RP2,MYRIP,NEK4,SPEF2,AKT1,SPATA18,FOPNL,CCSAP,CYS1,EZR,PRKAR2B,CEP162,DZIP1L,WDR11,CFAP45,TRAF3IP1,SPTBN5,PRKAR1A,TTC8,PIFO,USH1C,POC1B,MERTK,DHRS3,IFT27,DNAH3,SSX2IP,KIF5B,GNB5,ADRBK1,OCRL,KLC3,CNGA1,RPGR,GPR161,MYO5A,DNAI1,CASK,LCA5,CEP89,B9D2,CFAP46,SPA17,RAB3IP,AKAP3,NPHP3,BBS2,NUBP1,GNA11,MAP1B,RGS9,PROM1,PHLPP2,WDR19,AURKA,SSNA1,PKD2,CFAP20,CEP41,PROM2,EHD1,DRD1 |
| 3.994e-02 | -3.22 | CASP8 (caspase 8, apoptosis-related cysteine peptidase) | protein interactions | 841 | 132 | 29 | 16036 | 2547 |
CASP3,SORBS1,RHOA,RIPK2,RALBP1,TSC22D3,TRAF2,CASP9,XIAP,TP53,EZR,BCL2L1,ILK,MAP1LC3B,BCAP31,CASP4,FAS,RB1,FYN,CASP7,CTNNB1,CDH1,PTEN,HTT,BAX,PRKCI,CDKN1B,PDIA6,ATG4D |
| 3.994e-02 | -3.22 | positive regulation of axonogenesis | biological process | GO:0050772 | 68 | 16 | 16441 | 2455 |
RHOA,CRABP2,ILK,MAP1B,CDKL5,SEMA4D,MEGF8,LIMK1,NRG1,EFNA5,TNFRSF12A,NTN1,WNT3A,SHOX2,TIAM1,L1CAM |
| 3.994e-02 | -3.22 | negative regulation of protein binding | biological process | GO:0032091 | 68 | 16 | 16441 | 2455 |
EPB41L5,NKX3-1,PPARA,NES,AES,AURKB,PDGFB,PTPRF,CTNNBIP1,RALB,BAX,TMBIM6,SORL1,ADAM15,AURKA,IFIT1 |
| 3.994e-02 | -3.22 | regulation of bone mineralization | biological process | GO:0030500 | 68 | 16 | 16441 | 2455 |
ACVR1,WNT10B,SOX9,ANO6,PHOSPHO1,P2RX7,OSR2,FAM101B,BMP2K,BMP2,ENPP1,FAM20C,BMP7,TFAP2A,TWIST1,OSR1 |
| 3.994e-02 | -3.22 | regulation of calcium ion transmembrane transport | biological process | GO:1903169 | 68 | 16 | 16441 | 2455 |
CALM1,CALM3,ATP1B1,PRKACA,CACNB4,CALM2,GNB5,HTT,STIM1,CABP1,PLCG2,PKD2,TSPAN13,PDE4D,HSPA2,MYO5A |
| 3.995e-02 | -3.22 | p53-Dependent G1/S DNA damage checkpoint | REACTOME pathways | R-HSA-69580 | 57 | 14 | 8202 | 1235 |
CCNE2,PSMD1,PSMB4,PSME2,PSMD3,PSMC2,TP53,PSMD7,PSMD10,CDKN1B,PSME1,PSMC1,PSMA4,PSMA5 |
| 3.995e-02 | -3.22 | p53-Dependent G1 DNA Damage Response | REACTOME pathways | R-HSA-69563 | 57 | 14 | 8202 | 1235 |
CCNE2,PSMD1,PSMB4,PSME2,PSMD3,PSMC2,TP53,PSMD7,PSMD10,CDKN1B,PSME1,PSMC1,PSMA4,PSMA5 |
| 3.997e-02 | -3.22 | synovial_sarcoma | COSMIC cancer mutations | synovial_sarcoma | 92 | 20 | 17775 | 2585 |
SGCE,LCA5,AKT1,NR3C1,TP53,ERBB2,IDH1,TXNDC11,EGFR,PRX,SS18,RB1,DNAJC10,CTNNB1,CDH1,PTEN,CDK19,PIK3CA,SORL1,TRAF5 |
| 3.998e-02 | -3.22 | BRCA1 (breast cancer 1, early onset) | protein interactions | 672 | 522 | 98 | 16036 | 2547 |
ELK4,CASP3,TRIM24,SUZ12,XIAP,TP53,GATA3,MORF4L2,CCNB1,BARD1,TP73,CCND1,APLP2,PCNA,CCNA2,CTNNB1,UBE2T,LMO4,TUBG1,CRY2,KIF22,RTKN2,ASH2L,PPP1CA,CDKN2D,RNF169,TUBA4A,PLK1,MAP3K3,CDKN2AIP,SMARCA2,AKT1,CASP9,EZR,TFAP2C,CDCA2,ATP1B1,MYL12A,CDK1,VCP,PEX5,JAK1,RBL1,STAT1,PPP1CB,HDAC1,KPNA2,ARNT,PRKAA2,CMAS,LGALS3,DHPS,ETV5,POMGNT1,ETS1,SSX2IP,TOP2A,TFAP4,RB1,FLII,DAZAP1,CDK16,TFAP2A,MSH2,UBE2J1,H2AFY,BRD7,BRAT1,SLAIN2,PPP6R1,NCOA2,MSH6,HMMR,KIF20A,ZC3H11A,PIK3R1,FHL2,NPC2,FXR2,ELK1,BORA,RANBP9,DDX23,NCOA3,ETS2,NMI,ITPR1,UBE2D2,E2F1,AURKA,CSTF2,FBXO44,ATP1B3,USF2,AHR,AFAP1,CTBP1,RAD21 |
| 4.000e-02 | -3.22 | KIAA0368 (KIAA0368) | protein interactions | 23392 | 116 | 26 | 16036 | 2547 |
CPD,MOB4,CDKN2AIP,VPS11,TUBB4B,FBXO2,FLOT1,UBE2Q1,KDM3A,VPS26A,EGFR,DNAJB9,KIF5B,GAREM2,PSMD1,LYPD3,PSMD3,PSMC2,CKS1B,FBXO44,RP2,ARF6,FLOT2,HSPB1,PSMA5,GOLGB1 |
| 4.003e-02 | -3.22 | superpathway of melatonin degradation | BIOCYC pathways | HUMAN_PWY-6402 | 11 | 5 | 907 | 172 |
MAOA,CYP2U1,POR,CYP2S1,CYP1B1 |
| 4.008e-02 | -3.22 | V$AP1_Q4 | MSigDB lists | V$AP1_Q4 | 257 | 48 | 17758 | 2588 |
CMAS,TXN,SCOC,LRRFIP2,IGFBP6,CAMKK1,ETV5,RNF182,PLAC1,S100A2,LTBP3,ZNF385B,LMNA,PAK6,BMP2,IRAK1,SHC3,SLC16A6,KCNN4,NECAB3,TNFRSF12A,TAGLN2,PDE4D,TBC1D10B,MDFI,SMARCA2,ELK3,CASK,TRIM8,DSTN,PTPRH,DCHS1,KBTBD8,TMEM151A,CAPNS1,TCF7,KDM3A,TBC1D17,MPRIP,MAP2,LIMK1,CORO1C,S100A5,HS3ST3B1,EFNA1,UBE2C,LIFR,RTN3 |
| 4.009e-02 | -3.22 | negative regulation of immune system process | biological process | GO:0002683 | 365 | 67 | 16441 | 2455 |
GAS2L1,CASP3,LGR4,NLRX1,TSC22D3,INPP5D,TAP1,ERBB2,IL27RA,CD274,FLT3,CD46,NOV,CTNNB1,TSPAN6,IL31RA,BCL6,DLG1,DUSP10,DAB2IP,IFIT1,CD55,ITCH,PTGER4,EZR,ERBB2IP,ABR,PTPRJ,STAT6,AXL,HOXA9,TRAF3IP1,INPP4B,NOD2,F2RL1,PRKAR1A,LGALS3,UBASH3B,HLA-E,SOX9,SERPINB9,PKN1,MERTK,HLA-A,ADORA1,GATA2,PIK3AP1,FBXO7,TMBIM6,C10orf54,SOCS5,HES1,PSMB4,MICB,PIK3R1,PDE5A,BCL10,FAS,HLA-B,BANK1,NMI,NFKBIA,NLRC5,GPER1,JAK3,NDFIP1,IRF1 |
| 4.011e-02 | -3.22 | establishment or maintenance of epithelial cell apical/basal polarity | biological process | GO:0045197 | 32 | 9 | 16441 | 2455 |
ANK1,PTK7,DLG1,PRKCI,EZR,ERBB2IP,ILK,DLG3,ARF4 |
| 4.011e-02 | -3.22 | negative regulation of lymphocyte mediated immunity | biological process | GO:0002707 | 32 | 9 | 16441 | 2455 |
HLA-B,HLA-E,SERPINB9,BCL6,NOD2,TAP1,C10orf54,NDFIP1,HLA-A |
| 4.011e-02 | -3.22 | negative regulation of response to nutrient levels | biological process | GO:0032108 | 32 | 9 | 16441 | 2455 |
QSOX1,PINK1,PPARA,TP53,NENF,KANK2,CHMP4B,BBS2,LZTS1 |
| 4.011e-02 | -3.22 | negative regulation of response to extracellular stimulus | biological process | GO:0032105 | 32 | 9 | 16441 | 2455 |
QSOX1,PINK1,PPARA,TP53,NENF,KANK2,CHMP4B,BBS2,LZTS1 |
| 4.011e-02 | -3.22 | regulation of natural killer cell mediated cytotoxicity | biological process | GO:0042269 | 32 | 9 | 16441 | 2455 |
LAMP1,HLA-B,PVRL2,HLA-E,SERPINB9,TAP1,HLA-A,RASGRP1,SMAGP |
| 4.011e-02 | -3.22 | positive regulation of BMP signaling pathway | biological process | GO:0030513 | 32 | 9 | 16441 | 2455 |
HES1,CYR61,TWSG1,ACVRL1,GPC3,RNF165,C10orf54,ILK,NEO1 |
| 4.025e-02 | -3.21 | G-protein alpha-subunit binding | molecular function | GO:0001965 | 18 | 6 | 16491 | 2452 |
NUCB1,IGF1R,RGS14,F2R,F2RL1,DRD1 |
| 4.025e-02 | -3.21 | cysteine-type endopeptidase activator activity involved in apoptotic process | molecular function | GO:0008656 | 18 | 6 | 16491 | 2452 |
CDKN1B,CARD8,NKX3-1,BCL2L13,CTSC,NGFRAP1 |
| 4.025e-02 | -3.21 | aldehyde dehydrogenase (NAD) activity | molecular function | GO:0004029 | 18 | 6 | 16491 | 2452 |
ALDH7A1,ALDH5A1,ALDH2,ALDH6A1,ALDH3A2,ALDH1A3 |
| 4.026e-02 | -3.21 | V$OCT1_B | MSigDB lists | V$OCT1_B | 251 | 47 | 17758 | 2588 |
PAX6,SCOC,THRA,TSC22D3,IRX4,KCTD12,MRAS,MGAT5B,HPCAL4,SLC25A35,PPP2R3A,HDAC9,SESN3,ADORA1,PTEN,CYR61,LHX6,MITF,PRKG1,CNNM4,TWIST1,TSPAN13,PIK3CD,PDE4D,CPD,SH3BGRL,SERTAD4,STAT4,KIF13A,EAF2,LDB2,ITPR3,TP53INP2,RHOB,DPYSL3,CXXC4,TSC1,KLF12,GPRC5B,FAM117A,RHOBTB2,TMOD2,SP6,CEP41,ARHGAP4,TLL2,NR2C2 |
| 4.029e-02 | -3.21 | WANG_LSD1_TARGETS_UP | MSigDB lists | WANG_LSD1_TARGETS_UP | 23 | 7 | 17758 | 2588 |
MDK,EZR,PDGFA,IGFBP2,ELK3,CDKN1C,CSRP2 |
| 4.029e-02 | -3.21 | JIANG_TIP30_TARGETS_DN | MSigDB lists | JIANG_TIP30_TARGETS_DN | 23 | 7 | 17758 | 2588 |
CALR,ZYX,BLCAP,CTSD,CBX4,SIRPA,TP53 |
| 4.029e-02 | -3.21 | BIOCARTA_RAC1_PATHWAY | MSigDB lists | BIOCARTA_RAC1_PATHWAY | 23 | 7 | 17758 | 2588 |
PLD1,LIMK1,RALBP1,MYLK,CDK5R1,PIK3R1,PIK3CA |
| 4.029e-02 | -3.21 | ENDOSOME_TRANSPORT | MSigDB lists | ENDOSOME_TRANSPORT | 23 | 7 | 17758 | 2588 |
ZFYVE16,DOPEY2,TINAGL1,ABCA1,RHOB,M6PR,VPS4B |
| 4.029e-02 | -3.21 | PROTEASOME_COMPLEX | MSigDB lists | PROTEASOME_COMPLEX | 23 | 7 | 17758 | 2588 |
PSMD10,PSME1,PSMD1,PSME2,PSMD3,PSMC2,PSMD7 |
| 4.029e-02 | -3.21 | BIOCARTA_IGF1R_PATHWAY | MSigDB lists | BIOCARTA_IGF1R_PATHWAY | 23 | 7 | 17758 | 2588 |
PRKAR2B,IGF1R,AKT1,RPS6KA1,PIK3R1,PRKAR1A,PIK3CA |
| 4.029e-02 | -3.21 | REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | MSigDB lists | REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 23 | 7 | 17758 | 2588 |
RGS9,RGS5,RGS12,GRK6,RGS14,RGS3,RGS20 |
| 4.029e-02 | -3.21 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | MSigDB lists | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | 23 | 7 | 17758 | 2588 |
NCOA3,RUNX2,CTGF,NCOA2,TEAD3,WWTR1,PPARA |
| 4.029e-02 | -3.21 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | 23 | 7 | 17758 | 2588 |
GEM,CPEB4,CSNK1G1,GNE,ETV5,HDAC9,RAB23 |
| 4.029e-02 | -3.21 | BIOCARTA_CASPASE_PATHWAY | MSigDB lists | BIOCARTA_CASPASE_PATHWAY | 23 | 7 | 17758 | 2588 |
CASP3,ARHGDIB,CASP7,CASP4,CASP9,LMNA,XIAP |
| 4.029e-02 | -3.21 | BIOCARTA_CTCF_PATHWAY | MSigDB lists | BIOCARTA_CTCF_PATHWAY | 23 | 7 | 17758 | 2588 |
CDKN1B,TGFBR1,TGFBR3,PTEN,PIK3R1,PIK3CA,TP53 |
| 4.029e-02 | -3.21 | REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX | MSigDB lists | REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX | 23 | 7 | 17758 | 2588 |
MAP3K7,IRAK1,NFKB2,RIPK2,TAB3,NFKBIA,NOD2 |
| 4.042e-02 | -3.21 | negative regulation of leukocyte mediated immunity | biological process | GO:0002704 | 42 | 11 | 16441 | 2455 |
HLA-B,HLA-E,SERPINB9,BCL6,NOD2,TAP1,C10orf54,NDFIP1,JAK3,ABR,HLA-A |
| 4.042e-02 | -3.21 | forelimb morphogenesis | biological process | GO:0035136 | 42 | 11 | 16441 | 2455 |
RUNX2,CTNNB1,FMN1,HOXA9,TFAP2A,TWIST1,OSR2,CRABP2,OSR1,SHOX2,MECOM |
| 4.047e-02 | -3.21 | CATTGTYY_V$SOX9_B1 | MSigDB lists | CATTGTYY_V$SOX9_B1 | 343 | 62 | 17758 | 2588 |
BMF,TRIM2,HSPG2,KLHL13,ARFGEF1,NDRG2,HMGN3,BCL2L1,MGAT5B,TRIB2,SEPT4,VASH1,ETS1,PSIP1,SYTL2,PER2,HDAC9,CCDC92,FOXP2,WEE1,CALD1,LHX6,PAK2,RANBP1,MITF,ADAM15,DAB2IP,NOTCH3,TIAM1,SEPHS1,MDFI,DPYSL5,DOCK4,SUN2,ATL1,TGIF1,MBP,MOSPD2,SLC39A8,ITCH,PANK1,RGAG1,KIF1C,PRKCQ,KIF20B,ZFAND5,PDIK1L,RANBP9,MAPK8IP1,ARF4,MAP1B,NT5C2,ARHGEF19,FAT4,SLC25A40,MYLK,TLE1,EIF4EBP2,SPTBN5,NDST3,FOXA1,PHC1 |
| 4.050e-02 | -3.21 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_UP | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_UP | 179 | 35 | 17758 | 2588 |
BIN1,LZTFL1,HLA-F,ATP2C2,GATA3,TDRKH,CYB561,IL18,PHF1,ZFYVE9,ABCD4,SCML1,MARCH8,ZNF432,TRANK1,TSPAN6,RPL39,FAM13B,MDFIC,HLA-C,ECE1,THRB,NR3C1,DENND1B,PIK3R1,CXorf57,CLSTN1,MTRF1L,TCF7,EPHA1,LRRC1,FOXL1,KBTBD2,CSGALNACT1,MAP3K5 |
| 4.050e-02 | -3.21 | V$FREAC7_01 | MSigDB lists | V$FREAC7_01 | 179 | 35 | 17758 | 2588 |
RUNX2,FRMD4A,CPEB4,CHCHD7,ETV5,FLOT1,BEX2,SPTB,SCML1,IER3,KCTD15,CTGF,FLRT3,TWIST1,SSH3,TRIM8,CXXC5,ELK3,CTNNAL1,CBX6,RGAG1,NFIB,RHOB,VCP,NIN,MAGED2,COL13A1,NEIL3,PPP1CB,EFNA5,NRG1,CDAN1,ABCA1,DMPK,RGMA |
| 4.050e-02 | -3.21 | GSE3982_MAC_VS_BASOPHIL_DN | MSigDB lists | GSE3982_MAC_VS_BASOPHIL_DN | 179 | 35 | 17758 | 2588 |
REPS2,NDRG1,AKAP17A,SAMD9,MAP1LC3B,FLT3,PHF1,MARCH8,FRY,TRANK1,CNTRL,SRP54,RFX5,MANF,APOBEC3G,CTDSP2,FAM134C,SMC4,CD55,ADCK3,EIF2AK1,CASP4,NFIB,SFXN1,PRKAG2,RPL12,PDLIM3,ETS2,H1F0,UBE2D2,RYK,CHPT1,GAB1,TLL2,JARID2 |
| 4.050e-02 | -3.21 | NRL_DN.V1_UP | MSigDB lists | NRL_DN.V1_UP | 132 | 27 | 17758 | 2588 |
PCOLCE,SNTB2,RHBDL3,PPARA,PDIA5,NUF2,GALNT7,GPSM2,GRTP1,DHRS3,APC2,STK17B,RHPN1,SEC14L2,SNTA1,AHRR,CCNA2,LLGL2,KCNN4,SLC16A6,TRPC1,CNGA1,FAIM,TTC39C,SCN2A,ST3GAL1,STK35 |
| 4.053e-02 | -3.21 | Endothelin | WikiPathways | WP2197 | 34 | 10 | 4455 | 729 |
GNAS,CALM2,GUCY1B2,GNB5,CALM1,MYLK,CALCRL,CALM3,ECE1,EDNRA |
| 4.053e-02 | -3.21 | Cell cycle | KEGG pathways | hsa04110 | 124 | 27 | 6908 | 1076 |
CCNE2,PLK1,CDKN1C,CDC20,PTTG1,TP53,CUL1,PKMYT1,CCNB1,CDC25C,CDK1,CDKN2C,CCND1,RB1,WEE1,CCNA2,PCNA,CCNB3,RBL1,E2F1,HDAC1,CDKN1B,BUB1,CCNB2,CDKN2D,ESPL1,RAD21 |
| 4.053e-02 | -3.21 | Cell cycle | KEGG pathways | ko04110 | 124 | 27 | 6908 | 1076 |
CCNE2,PLK1,CDKN1C,CDC20,PTTG1,TP53,CUL1,PKMYT1,CCNB1,CDC25C,CDK1,CDKN2C,CCND1,RB1,WEE1,CCNA2,PCNA,CCNB3,RBL1,E2F1,HDAC1,CDKN1B,BUB1,CCNB2,CDKN2D,ESPL1,RAD21 |
| 4.058e-02 | -3.20 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | MSigDB lists | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | 43 | 11 | 17758 | 2588 |
RASGRF1,ARHGEF3,ARHGEF11,ARHGAP4,TIAM1,ARHGEF9,ABR,ARHGEF16,ARHGEF4,FGD1,NGEF |
| 4.058e-02 | -3.20 | GNATENKO_PLATELET_SIGNATURE | MSigDB lists | GNATENKO_PLATELET_SIGNATURE | 43 | 11 | 17758 | 2588 |
GNAS,CD99,HLA-E,PGRMC1,FTH1,TAGLN2,HLA-C,NRGN,MYL12A,ITGA2B,TUBA4A |
| 4.058e-02 | -3.20 | PID_INTEGRIN3_PATHWAY | MSigDB lists | PID_INTEGRIN3_PATHWAY | 43 | 11 | 17758 | 2588 |
SPP1,CYR61,PLAUR,SDC4,F11R,COL4A5,ITGAV,SDC1,PDGFB,L1CAM,ITGA2B |
| 4.058e-02 | -3.20 | ZHAN_MULTIPLE_MYELOMA_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD2_UP | 43 | 11 | 17758 | 2588 |
B3GALNT1,TGIF1,APLP2,SORT1,PTPRJ,PIK3AP1,RCBTB2,PHLPP2,PRDM5,DHTKD1,TRAF5 |
| 4.058e-02 | -3.20 | positive regulation of sodium ion transport | biological process | GO:0010765 | 37 | 10 | 16441 | 2455 |
PRSS8,SCN5A,AKT1,SGK3,DNM2,SGK1,PKP2,ATP1B1,ATP1B3,CHP1 |
| 4.058e-02 | -3.20 | lung epithelium development | biological process | GO:0060428 | 37 | 10 | 16441 | 2455 |
THRB,KLF2,GRHL2,THRA,SOX9,GPSM2,SAV1,LTA4H,NFIB,FOXA1 |
| 4.058e-02 | -3.20 | porphyrin-containing compound metabolic process | biological process | GO:0006778 | 37 | 10 | 16441 | 2455 |
FECH,CYP1A1,BLVRB,NFE2L1,SLC11A2,EIF2AK1,BLVRA,SLC25A38,SPTB,RSAD1 |
| 4.066e-02 | -3.20 | GSE13229_MATURE_VS_INTMATURE_NKCELL_UP | MSigDB lists | GSE13229_MATURE_VS_INTMATURE_NKCELL_UP | 185 | 36 | 17758 | 2588 |
NKX3-1,PARP12,LGALS3,TMEM86B,ETNK1,ATP6V1E2,CD274,HERC6,SH3KBP1,PPP2R3A,MUC16,IGF1R,TACC2,KCNN4,MCF2L,ARVCF,ECE1,PACSIN1,EGLN3,MOXD1,MDFI,SNX7,DLGAP1,MFI2,STAT4,MGAT4B,STEAP1,KDM4D,SLC25A4,FGFR2,MFSD2A,SPINT2,PKD2,HOOK1,SHOX2,FAM134B |
| 4.066e-02 | -3.20 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | 185 | 36 | 17758 | 2588 |
UGP2,GPR107,TRIP10,SLC1A3,OSR2,BCL2L1,GNB2,CMTM6,CHST2,SIRPA,MXD1,RND1,SGPL1,VASP,ITGB8,PIK3AP1,FJX1,TNIP1,TMTC2,RNF19B,STK17B,DCP2,NIN,PTPRJ,PVRL2,STK38,RAP2C,SLC2A6,ARRB1,NFKBIZ,CTNND1,EFNA1,SERPINB1,KLF7,EHD1,IRF1 |
| 4.066e-02 | -3.20 | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP | 185 | 36 | 17758 | 2588 |
KLF2,SIGIRR,PPFIBP2,TP53I11,DDR1,CYP1A1,GNB5,CES2,KIF13B,DDHD2,FBXO7,DNM2,DUSP10,KLF9,CNPY3,PRODH,MBP,ELK1,C15orf39,DOCK5,CDK5R1,MAN2A2,HLA-B,BTG1,BANK1,NAT1,FAM3C,ARAP1,RAB11FIP1,TMEM159,MAP3K5,STARD13,NR3C2,MAFF,CTDSP1,IRF1 |
| 4.069e-02 | -3.20 | Hepatitis B | KEGG pathways | hsa05161 | 146 | 31 | 6908 | 1076 |
DDX58,CCNE2,CASP3,DDB2,HSPG2,AKT1,STAT4,CASP9,PIK3R1,TP53,TGFBR1,EGR3,ELK1,FOS,FAS,CCND1,RB1,PCNA,CCNA2,JAK1,PTEN,STAT6,NFKBIA,STAT1,BAX,E2F1,PIK3CA,CDKN1B,IRF7,PIK3CD,IFIH1 |
| 4.070e-02 | -3.20 | regulation of leukocyte cell-cell adhesion | biological process | GO:1903037 | 287 | 54 | 16441 | 2455 |
CASP3,LGALS3,DHPS,IL15,HLA-E,TRAF2,GATA3,ERBB2,IL18,EGR3,CD274,TNFSF9,EFNB1,HLA-A,CD46,RAC2,CTNNB1,IL6ST,PAK2,BCL6,PIK3CA,DLG1,IGFBP2,C10orf54,MAP3K7,RAG1,FLOT2,SYK,RASGRP1,SOCS5,HES1,SOD1,CD55,RHOA,RIPK2,AKT1,LGALS8,ITCH,PIK3R1,PPARA,PDE5A,PRKCQ,YES1,SOX13,BCL10,CD83,FYN,NOD2,NR4A3,ICOSLG,NDFIP1,JAK3,PRKAR1A,IRF1 |
| 4.073e-02 | -3.20 | Frizzled_dom | interpro domains | IPR020067 | 23 | 7 | 18293 | 2672 |
COL18A1,ROR1,FZD5,FZD4,FZD7,FZD6,SMO |
| 4.073e-02 | -3.20 | Spectrin_repeat | interpro domains | IPR002017 | 23 | 7 | 18293 | 2672 |
SPTBN5,DRP2,SYNE3,SPTB,MCF2L,SYNE2,UTRN |
| 4.073e-02 | -3.20 | TIMP-like_OB-fold | interpro domains | IPR008993 | 23 | 7 | 18293 | 2672 |
NTN4,TIMP3,PCOLCE,TIMP2,NTN1,TIMP1,AGRN |
| 4.075e-02 | -3.20 | LU_IL4_SIGNALING | MSigDB lists | LU_IL4_SIGNALING | 92 | 20 | 17758 | 2588 |
QSOX1,SMARCA2,PHF20L1,ARAP2,MRPS15,STAT4,SELL,RASGRP3,CMTM6,SPAG1,GNAS,NCOA3,CTGF,SPINT2,BCL6,APPL2,NFKBIZ,MAP3K5,CTSD,RRAGD |
| 4.077e-02 | -3.20 | GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_UP | 191 | 37 | 17758 | 2588 |
OTUD5,MYL9,KIF3C,TCF25,JKAMP,FBXO2,OSGIN2,GALM,B4GALT4,HDAC6,CHST2,TMCC3,AKIRIN1,ADD3,SRPX,PIK3AP1,NPNT,PCYOX1,ABCA2,SGCB,SNX10,KIF20A,GCLC,SERTAD3,ICMT,PTGFRN,CDK5R1,NT5C2,CARHSP1,BFSP1,TWSG1,AREG,AXL,ATP1B3,SGOL1,SLC31A2,COL16A1 |
| 4.077e-02 | -3.20 | GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDM_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDM_DN | 191 | 37 | 17758 | 2588 |
MRPS15,RHBDL3,MMADHC,PRSS22,LTBP3,BTG3,SHC3,KCNN4,BHLHE41,RPL39,MITF,FCHO1,H2AFY,PSMA5,SOAT1,HMMR,PLEKHA6,CELSR2,CDC20,PPARA,SYP,KLK6,ATP8B3,GNAS,TMEM50B,GDE1,WFS1,DOLPP1,NR4A3,SPAG7,CLIP4,DYSF,PRKCDBP,MAPK13,RPL22,ST3GAL1,CPPED1 |
| 4.077e-02 | -3.20 | GSE3982_MAST_CELL_VS_TH2_DN | MSigDB lists | GSE3982_MAST_CELL_VS_TH2_DN | 191 | 37 | 17758 | 2588 |
PPP1R2,EPAS1,MPZL1,FOXM1,MRPS15,CENPI,SDC4,DGKA,ABCG2,MORC4,IL27RA,NFAT5,APOBEC3B,FRYL,FUT8,MSH2,CKS1B,MAPK11,PXMP4,ETHE1,NUP85,ALDH3A2,SMC4,HP1BP3,PLK1,TDP1,MAPKAPK3,CASP9,KIF20B,BORA,SFXN1,PRDX3,INPP4B,AURKA,ETAA1,PIEZO1,NUP37 |
| 4.077e-02 | -3.20 | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN | 191 | 37 | 17758 | 2588 |
GRN,HECA,BMF,ANKRD13D,LFNG,RPS6KA1,CCM2,SMARCAL1,IL27RA,FAM78A,PCBP1,GNB2,CXCL16,PIK3CD,PPP1CA,MAP3K3,SUN2,TRIM8,TACC1,EMP3,RUNX3,TNFAIP8L1,NPC2,FAM73B,CBL,KCTD2,FUCA1,PVRL2,ATXN7L3,SH2D3C,RAB31,ARRB1,CTNND1,PLIN3,SRSF9,DIS3L,CTDSP1 |
| 4.077e-02 | -3.20 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 191 | 37 | 17758 | 2588 |
CCNC,CDS2,MRPL44,LACTB2,CRABP2,MESDC2,PSMD1,PFKL,SIVA1,ARL1,CAPG,NEK2,BUB1,MDFIC,AHCY,LMAN1,PDIA6,NUP85,S100A6,PMPCB,CLCN3,PGM1,PLSCR1,GUSB,SH3BGRL,HTATIP2,NUSAP1,BLVRA,ALCAM,C4orf27,GABARAPL1,PRDX4,CDCA4,TIMM8A,PGRMC1,KPNA2,SSNA1 |
| 4.077e-02 | -3.20 | GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_UP | 191 | 37 | 17758 | 2588 |
ARHGEF3,ACVR1,HSP90B1,ARL4C,DGKA,PDIA3,HMGN3,GTF3A,DAZAP1,RNF220,NUP210,ATP5H,FBXO7,BRD7,AKR1B1,MDFIC,NUP85,UPF3A,NAGPA,SUN2,TGIF1,ASXL1,LGALS8,UXT,PIK3R1,COX11,GLO1,MRPS35,EIF2AK1,RNF113A,SLC25A5,FYN,IARS2,HDAC1,FAM117A,CD81,SLC25A38 |
| 4.087e-02 | -3.20 | lung-carcinoma-mucoepidermoid_carcinoma | COSMIC cancer mutations | lung-carcinoma-mucoepidermoid_carcinoma | 81 | 18 | 17775 | 2585 |
BIN1,LRRFIP2,ERBB2,C12orf65,TRAPPC8,ERBB2IP,PRKRA,EGFR,TSEN34,MMP15,KIF5B,KIAA1107,CDH1,CCDC6,ZDHHC20,GLB1,TINAGL1,KDELC2 |
| 4.089e-02 | -3.20 | COL6A1 (collagen, type VI, alpha 1) | protein interactions | 1291 | 17 | 6 | 16036 | 2547 |
PDIA3,PDGFA,DNAJB11,FBXO6,PDGFB,LGALS3BP |
| 4.089e-02 | -3.20 | NDFIP2 (Nedd4 family interacting protein 2) | protein interactions | 54602 | 17 | 6 | 16036 | 2547 |
SLC11A2,FYN,PTEN,ITCH,EGFR,WWP2 |
| 4.089e-02 | -3.20 | PTPRA (protein tyrosine phosphatase, receptor type, A) | protein interactions | 5786 | 17 | 6 | 16036 | 2547 |
PTPRF,FYN,LGALS8,HSPB1,BCAR1,CALM1 |
| 4.089e-02 | -3.20 | ECM1 (extracellular matrix protein 1) | protein interactions | 1893 | 17 | 6 | 16036 | 2547 |
GMCL1,HSPG2,CA8,FBLN1,CPTP,BNIP3L |
| 4.089e-02 | -3.20 | RAB25 (RAB25, member RAS oncogene family) | protein interactions | 57111 | 17 | 6 | 16036 | 2547 |
MYO5B,TGFBR1,ACVR1,RAB11FIP2,OPTN,RAB11FIP1 |
| 4.089e-02 | -3.20 | NGLY1 (N-glycanase 1) | protein interactions | 55768 | 17 | 6 | 16036 | 2547 |
FBXO6,B4GALT4,GUCD1,EGFR,VCP,RAD23A |
| 4.089e-02 | -3.20 | DUSP3 (dual specificity phosphatase 3) | protein interactions | 1845 | 17 | 6 | 16036 | 2547 |
PDGFA,CASK,SYK,EGFR,STAT1,BNIP3L |
| 4.089e-02 | -3.20 | TCEB3B (transcription elongation factor B polypeptide 3B (elongin A2)) | protein interactions | 51224 | 17 | 6 | 16036 | 2547 |
ZNF165,CEP70,TCEB2,CBX5,TRAF2,DVL2 |
| 4.089e-02 | -3.20 | MYLK (myosin light chain kinase) | protein interactions | 4638 | 17 | 6 | 16036 | 2547 |
CTTN,HSPB1,PAK2,CALM1,CAMK2G,TP53 |
| 4.089e-02 | -3.20 | KCTD12 (potassium channel tetramerization domain containing 12) | protein interactions | 115207 | 17 | 6 | 16036 | 2547 |
KCTD12,DNPEP,RIPK2,GNE,LMNA,ARAP1 |
| 4.089e-02 | -3.20 | AKAP12 (A kinase (PRKA) anchor protein 12) | protein interactions | 9590 | 17 | 6 | 16036 | 2547 |
DYNLRB1,FHL1,ADRBK1,SPRTN,EGFR,TP53 |
| 4.089e-02 | -3.20 | SLC25A32 (solute carrier family 25 (mitochondrial folate carrier), member 32) | protein interactions | 81034 | 17 | 6 | 16036 | 2547 |
PLS1,LASP1,UBE2T,NIPSNAP3A,DBI,CTH |
| 4.089e-02 | -3.20 | ESPL1 (extra spindle pole bodies like 1, separase) | protein interactions | 9700 | 17 | 6 | 16036 | 2547 |
PPP2R5A,CCNB1,CDK1,PTTG1,VCP,CKS2 |
| 4.089e-02 | -3.20 | TRPV4 (transient receptor potential cation channel, subfamily V, member 4) | protein interactions | 59341 | 17 | 6 | 16036 | 2547 |
FYN,YES1,PACSIN2,PACSIN1,ITCH,CALM1 |
| 4.097e-02 | -3.19 | CRHBP (corticotropin releasing hormone binding protein) | protein interactions | 1393 | 9 | 4 | 16036 | 2547 |
PLS1,TNIP1,CCNB2,PHLDB3 |
| 4.097e-02 | -3.19 | SOCS5 (suppressor of cytokine signaling 5) | protein interactions | 9655 | 9 | 4 | 16036 | 2547 |
CASP3,TMBIM1,EGFR,DCUN1D1 |
| 4.097e-02 | -3.19 | CCNF (cyclin F) | protein interactions | 899 | 9 | 4 | 16036 | 2547 |
CUL1,NUSAP1,CCNB1,CDK1 |
| 4.097e-02 | -3.19 | SLC30A1 (solute carrier family 30 (zinc transporter), member 1) | protein interactions | 7779 | 9 | 4 | 16036 | 2547 |
DIRAS3,LGALS3,LGALS8,CSGALNACT1 |
| 4.097e-02 | -3.19 | RAB27B (RAB27B, member RAS oncogene family) | protein interactions | 5874 | 9 | 4 | 16036 | 2547 |
SYTL4,MLPH,DHPS,SYTL2 |
| 4.097e-02 | -3.19 | PODXL (podocalyxin-like) | protein interactions | 5420 | 9 | 4 | 16036 | 2547 |
SELL,LGALS3,LGALS8,SLC9A3R2 |
| 4.097e-02 | -3.19 | TDRD7 (tudor domain containing 7) | protein interactions | 23424 | 9 | 4 | 16036 | 2547 |
CDK17,FAM64A,TACC1,TDRD7 |
| 4.097e-02 | -3.19 | PCCA (propionyl-CoA carboxylase alpha subunit) | protein interactions | 5095 | 9 | 4 | 16036 | 2547 |
SGK1,PCCB,IFIT1,LGALS3 |
| 4.097e-02 | -3.19 | HACL1 (2-hydroxyacyl-CoA lyase 1) | protein interactions | 26061 | 9 | 4 | 16036 | 2547 |
PTPRF,WDFY1,PEX5,ZMYND19 |
| 4.097e-02 | -3.19 | DGKE (diacylglycerol kinase, epsilon 64kDa) | protein interactions | 8526 | 9 | 4 | 16036 | 2547 |
ARRB1,NUF2,MRPL44,TSPAN17 |
| 4.097e-02 | -3.19 | IL18 (interleukin 18) | protein interactions | 3606 | 9 | 4 | 16036 | 2547 |
CASP3,CASK,IL18R1,CASP4 |
| 4.097e-02 | -3.19 | TBC1D1 (TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1) | protein interactions | 23216 | 9 | 4 | 16036 | 2547 |
ROR1,HSPB1,BARD1,GABARAPL1 |
| 4.097e-02 | -3.19 | MYH3 (myosin, heavy chain 3, skeletal muscle, embryonic) | protein interactions | 4621 | 9 | 4 | 16036 | 2547 |
CUL1,IGSF8,ICAM1,CDCA8 |
| 4.097e-02 | -3.19 | WISP2 (WNT1 inducible signaling pathway protein 2) | protein interactions | 8839 | 9 | 4 | 16036 | 2547 |
AMZ2,HDAC1,IGF1R,TRIM68 |
| 4.097e-02 | -3.19 | KLK10 (kallikrein related peptidase 10) | protein interactions | 5655 | 9 | 4 | 16036 | 2547 |
SUSD3,GMCL1,LRIF1,BCAP31 |
| 4.097e-02 | -3.19 | Ppp1r10 (protein phosphatase 1, regulatory subunit 10) | protein interactions | 52040 | 9 | 4 | 16036 | 2547 |
PPP1CB,PPP1CA,PPP1R2,PPP1R10 |
| 4.097e-02 | -3.19 | HIBADH (3-hydroxyisobutyrate dehydrogenase) | protein interactions | 11112 | 9 | 4 | 16036 | 2547 |
MDH1,SOD1,PDXK,ALDH6A1 |
| 4.097e-02 | -3.19 | ETHE1 (ethylmalonic encephalopathy 1) | protein interactions | 23474 | 9 | 4 | 16036 | 2547 |
HDAC1,LRIF1,IDH1,TP53 |
| 4.097e-02 | -3.19 | TM4SF20 (transmembrane 4 L six family member 20) | protein interactions | 79853 | 9 | 4 | 16036 | 2547 |
CAB39,RHOA,TMEM43,FAM210B |
| 4.097e-02 | -3.19 | SLC9A2 (solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2) | protein interactions | 6549 | 9 | 4 | 16036 | 2547 |
RASA1,SLC9A2,PIK3R1,CHP1 |
| 4.097e-02 | -3.19 | MINPP1 (multiple inositol-polyphosphate phosphatase 1) | protein interactions | 9562 | 9 | 4 | 16036 | 2547 |
CD274,CYP1A1,FBXO6,LYPD6 |
| 4.097e-02 | -3.19 | SLPI (secretory leukocyte peptidase inhibitor) | protein interactions | 6590 | 9 | 4 | 16036 | 2547 |
GRN,CTSL,PLSCR1,CTSB |
| 4.099e-02 | -3.19 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-polycythaemia_vera | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-polycythaemia_vera | 375 | 67 | 17775 | 2585 |
AK7,BROX,ETNK1,TP53,FLT3,ECI1,SPTB,PDGFA,MUC16,MUC4,SP100,TACC2,CYP4F11,FRYL,IL6ST,IL31RA,PIK3CA,PHKA2,TLN2,NFKB2,MYRIP,CENPA,AKT1,ASXL1,SYNE2,CBL,TANC1,IDH1,RNF19B,ATP10D,ARHGEF26,AHRR,TNS4,JAK1,MADD,SPTBN5,APBA2,RTN3,ZC3HC1,SH3D19,HABP4,NKRF,PLPPR4,MECOM,CALR,RB1,GATA2,PTEN,TMEM62,PCYOX1,GAD1,SYK,ARAP2,WDR72,ASPM,RAPGEF2,PIK3R1,KIAA1109,UNC45B,RGS9,DYSF,CSTF2,LTBP2,PLD1,SLC25A38,JAK3,RAD21 |
| 4.099e-02 | -3.19 | polycythaemia_vera | COSMIC cancer mutations | polycythaemia_vera | 375 | 67 | 17775 | 2585 |
AK7,BROX,ETNK1,TP53,FLT3,ECI1,SPTB,PDGFA,MUC16,MUC4,SP100,TACC2,CYP4F11,FRYL,IL6ST,IL31RA,PIK3CA,PHKA2,TLN2,NFKB2,MYRIP,CENPA,AKT1,ASXL1,SYNE2,CBL,TANC1,IDH1,RNF19B,ATP10D,ARHGEF26,AHRR,TNS4,JAK1,MADD,SPTBN5,APBA2,RTN3,ZC3HC1,SH3D19,HABP4,NKRF,PLPPR4,MECOM,CALR,RB1,GATA2,PTEN,TMEM62,PCYOX1,GAD1,SYK,ARAP2,WDR72,ASPM,RAPGEF2,PIK3R1,KIAA1109,UNC45B,RGS9,DYSF,CSTF2,LTBP2,PLD1,SLC25A38,JAK3,RAD21 |
| 4.100e-02 | -3.19 | Golgi to endosome transport | biological process | GO:0006895 | 18 | 6 | 16441 | 2455 |
TGOLN2,AP1AR,DOPEY2,RAB29,SORT1,WIPI1 |
| 4.100e-02 | -3.19 | filopodium assembly | biological process | GO:0046847 | 18 | 6 | 16441 | 2455 |
FGD6,EZR,ITGA6,ARHGEF4,SPATA13,FGD1 |
| 4.100e-02 | -3.19 | mast cell mediated immunity | biological process | GO:0002448 | 18 | 6 | 16441 | 2455 |
PIK3CD,GATA2,S100A13,SERPINB9,RASGRP1,NR4A3 |
| 4.100e-02 | -3.19 | renal system vasculature development | biological process | GO:0061437 | 18 | 6 | 16441 | 2455 |
ACTA2,PKD2,HES1,NOTCH3,OSR1,PDGFB |
| 4.100e-02 | -3.19 | branch elongation of an epithelium | biological process | GO:0060602 | 18 | 6 | 16441 | 2455 |
TFAP2C,AREG,TMTC3,FGFR2,SPRY2,SOX9 |
| 4.100e-02 | -3.19 | microvillus assembly | biological process | GO:0030033 | 18 | 6 | 16441 | 2455 |
FXYD5,EZR,KLF5,STK26,RAPGEF2,RAP2C |
| 4.100e-02 | -3.19 | lymphocyte apoptotic process | biological process | GO:0070227 | 18 | 6 | 16441 | 2455 |
PKN1,AKT1,SIVA1,FAS,BCL10,BAX |
| 4.100e-02 | -3.19 | positive regulation of chondrocyte differentiation | biological process | GO:0032332 | 18 | 6 | 16441 | 2455 |
LOXL2,RUNX2,ACVRL1,POR,SOX9,FGF18 |
| 4.100e-02 | -3.19 | kidney vasculature development | biological process | GO:0061440 | 18 | 6 | 16441 | 2455 |
ACTA2,PKD2,HES1,NOTCH3,OSR1,PDGFB |
| 4.100e-02 | -3.19 | positive regulation of alpha-beta T cell proliferation | biological process | GO:0046641 | 18 | 6 | 16441 | 2455 |
IL18,CD55,RIPK2,SYK,HLA-E,HLA-A |
| 4.102e-02 | -3.19 | positive regulation of ligase activity | biological process | GO:0051351 | 101 | 22 | 16441 | 2455 |
PLK1,GCLM,PINK1,PSMB4,PSME2,CDC20,PSMD7,CUL1,PSMD10,PSME1,CCNB1,PSMA4,CDK1,MID1IP1,PSMD1,PTEN,PSMD3,PSMC2,DCUN1D1,UBE2C,PSMC1,PSMA5 |
| 4.104e-02 | -3.19 | astrocytoma | COSMIC cancer mutations | astrocytoma | 38 | 10 | 17775 | 2585 |
CDKN2C,ACVR1,NF2,CTNNB1,AKT1,PTEN,PIK3CA,TP53,IDH1,EGFR |
| 4.117e-02 | -3.19 | p53-like_TF_DNA-bd | interpro domains | IPR008967 | 43 | 11 | 18293 | 2672 |
TP73,RUNX2,STAT6,TBX1,STAT4,TBX18,STAT1,TP53,RUNX3,NFKB2,NFAT5 |
| 4.124e-02 | -3.19 | UGDH (UDP-glucose 6-dehydrogenase) | protein interactions | 7358 | 35 | 10 | 16036 | 2547 |
SIRT1,NAAA,TGOLN2,GGH,RNASEH2A,CTTN,PDIA6,PRKACA,HSPB1,FAS |
| 4.124e-02 | -3.19 | ATP2B4 (ATPase, Ca++ transporting, plasma membrane 4) | protein interactions | 493 | 35 | 10 | 16036 | 2547 |
CASK,ATP1A1,LGALS3,LGALS8,LYPD3,ATP9A,CD22,DLG1,ERBB2IP,DLG3 |
| 4.124e-02 | -3.19 | FAM189B (family with sequence similarity 189, member B) | protein interactions | 10712 | 35 | 10 | 16036 | 2547 |
SNTA1,CYHR1,CFAP74,ANKRD13D,FAM189A2,HLA-E,ITCH,SPINT2,WWP1,TSPAN17 |
| 4.124e-02 | -3.19 | TBXA2R (thromboxane A2 receptor) | protein interactions | 6915 | 35 | 10 | 16036 | 2547 |
GNAS,RHOA,SIVA1,PRKG1,GRK6,PKN1,PLCB2,PRKACA,GNA11,PRDX4 |
| 4.124e-02 | -3.19 | - | gene3d domains | 1.10.540.10 | 13 | 5 | 9988 | 1574 |
ACADM,ACOX2,ACADSB,ACAD8,ACAD10 |
| 4.126e-02 | -3.19 | IRS1 (insulin receptor substrate 1) | protein interactions | 3667 | 90 | 21 | 16036 | 2547 |
SIRT1,AKT1,PTPRU,PIK3R1,ERBB2,PRKCQ,BCL2L1,CBL,EGFR,SOCS3,IRS2,PTPRF,FYN,INSR,IGF1R,JAK1,CDH1,PLCG2,PIK3CA,JAK3,DVL2 |
| 4.127e-02 | -3.19 | sodium ion transmembrane transport | biological process | GO:0035725 | 90 | 20 | 16441 | 2455 |
SCN5A,TRAPPC10,ANO6,ATP1B1,SLC20A1,SLC8B1,SLC9A2,SLC9A7,SCNN1A,ATP1A1,SLC4A4,KCNK1,SLC9A6,CNNM4,PKD2,ATP1B3,SCN2A,SHROOM2,SLC12A2,HCN3 |
| 4.128e-02 | -3.19 | MODULE_164 | MSigDB lists | MODULE_164 | 59 | 14 | 17758 | 2588 |
ANXA3,APLP2,TIMP2,TIMP3,CDKN1C,TIMP1,DNAJC3,SPINT2,CST3,SERPINB5,SERPINB6,COL7A1,SERPINB1,PKIA |
| 4.128e-02 | -3.19 | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | MSigDB lists | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | 59 | 14 | 17758 | 2588 |
CARHSP1,ANK1,MMD,ZNF395,TMX4,FAM3C,CD9,MORC4,ARRB1,PRKAR2B,OSTF1,EPB41L4B,NTAN1,FAM69A |
| 4.129e-02 | -3.19 | TPR_1 | pfam domains | PF00515 | 52 | 13 | 16629 | 2504 |
TTC21B,TTC8,TMTC1,RGPD5,PEX5,DNAJC3,TTC7A,IFIT1,TTC9,TMTC2,IFIT3,UNC45B,SPAG1 |
| 4.135e-02 | -3.19 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | 2863 | 447 | 17775 | 2585 |
FAM171B,HECA,ACACB,GAA,PPP4R4,TSC22D3,KLC2,TAP1,NRG2,PDGFRL,BAIAP3,CCNB1,DPP8,FAM46C,KIF26A,SLC35E4,CDKN2C,DAPK2,ZYX,ARHGAP42,TGFBR3,CTGF,KIAA1107,DNAH6,STIM1,IQCE,CABP1,PAQR5,SLC46A1,IL31RA,AOX1,STEAP2,PIK3CA,ATRNL1,MTMR11,TMEM37,TIAM1,CPE,ODF2L,XKR8,NEK4,SPEF2,HSPA12A,TMEM98,TNS1,LDB2,SPNS3,ABR,ARHGEF26,AHRR,MPRIP,WDR11,ANKRD6,ATP7B,CELF5,MYLK,LRIG1,FAM114A1,NOD2,PRDM5,RNASEL,RELL1,STARD13,GAB1,ANXA11,ZNF720,DLAT,DDX58,SCN5A,MRC2,FRMD4A,CDKN1C,TBC1D1,CALB2,MTL5,ZNRF3,SLC1A3,NOTCH2,MERTK,SH3RF2,RAVER2,DOPEY2,RALGPS2,ITGA3,FAM189A1,MEGF8,PRKG1,SORL1,CADPS2,STT3B,CACNA1D,MOXD1,KCTD3,RIMS2,MCCC2,DNAI1,TRAK2,PRODH,KCNJ12,KLK5,LPGAT1,MYBL2,WHSC1,CALCRL,KIF20B,ATP8B3,NPHP3,SFXN5,NFIB,DCP2,PDE11A,FAS,CACHD1,AP1AR,PLEKHH2,FAAH,ISM1,TCEAL4,MPP2,NDE1,MAP3K5,TRPC3,PKD1L2,DOCK9,MFSD3,PLEKHG3,GPR107,S100A11,IQGAP1,RALBP1,RNF182,MGST2,FLT3,DDR1,ART5,ZNF385B,CDS1,CCND1,MUC16,SCNN1A,MYT1,SCN3A,MYO5B,MX1,SEC23A,FOXJ2,DRAP1,SYNE2,UTRN,DNAJB14,PYGO1,CBL,ATP10D,GIGYF1,PRDM11,FYN,PDLIM3,JAK1,ACAD10,SHROOM3,WFS1,WWTR1,INPP4B,TRIOBP,ZNF704,NRG1,NR3C2,COBL,ARNT,MRPS9,FARP1,PLSCR4,TAOK2,FAM189A2,SLC41A1,TRAF2,PDIA3,EFHD2,GPR180,SEPP1,PNPLA5,ICAM1,NEO1,WWP2,SLC25A36,SNTA1,ANK1,FUT2,OXCT1,ANKS1B,CTSC,KNDC1,KCNK5,FAM20B,ATP8B1,WWP1,MAP3K7,NCOA2,SMC4,RASGRF1,PDGFC,PLSCR1,FAM160A1,FMN1,RAPGEF2,MFSD2B,PIK3R1,CXorf57,AK4,DIAPH2,YES1,GRTP1,ARSK,ABLIM2,TXK,RPL12,MAMDC4,KIAA0141,RAB11FIP2,ZFP30,ABCB1,ARSB,USF2,CXorf56,OCLN,TLL2,EXPH5,LTBP1,LMCD1,VARS2,PLAC1,MPP5,ITPR2,CDIPT,PDGFB,DNER,KREMEN1,TMC1,DENND2D,PLS3,ARHGEF10L,NKAIN3,ADPRHL1,SIPA1L2,ENTPD4,CASC4,ARHGEF37,SHC3,NPNT,IMPAD1,SLC44A1,DDHD2,ANKFN1,DLG1,DUSP10,RP2,ARNT2,MYH14,ANO4,MYRIP,BTBD3,IL1RAP,RASGRP1,ZNF462,MCTP1,CELSR2,ASXL1,FOPNL,NFE2L1,RNF165,RGAG1,ANLN,SESN1,PTGFRN,VCP,EDNRA,DPYSL3,MDK,MAN2A2,PLCH1,MFAP3L,NEIL1,GPRC5B,KLF12,MAP2,TDRD7,CTNND1,KLF11,EPB41L4A,GLCCI1,HS6ST3,PRKAA2,LASP1,USH1C,PPP1R12A,BVES,HLA-F,ELOVL7,CNTNAP2,SAMD9,PHLPP1,IL18R1,ANO1,RB1,PFKL,FRAS1,FNIP1,SRP54,MDFIC,LIMCH1,PIM1,ALS2CL,SNED1,MDFI,CHSY3,WDR72,RGMB,PARD3B,PDE5A,HMG20B,EIF2AK1,KIAA1109,PRRC1,UNC45B,ANKRD29,AMDHD1,SOX13,RASGRP2,INSR,UTP14C,ALPK3,NXPH4,CTSA,LTBP2,PLD1,SEMA3A,CDAN1,COL16A1,NIPA1,FAM45A,USP43,NCKAP5,ZSWIM5,NF2,FOXM1,SOD2,TP53,P2RX7,TDRKH,OSR2,MICALL2,STIL,CDK14,CYP4F11,TACC2,FRYL,N4BP3,GYS1,RPN2,STEAP3,EGLN3,ETHE1,F2R,MBP,ERBB2IP,TMTC2,DOCK5,TAPBP,RTN4RL1,BFSP1,PTK7,ADAMTS14,TLE1,MAOA,CHMP4B,RCAN2,EFNA5,SPTBN5,IRF7,CYP2U1,NDST3,LIFR,KDELC2,FAM134B,CDS2,TRAPPC10,TSPAN15,POC1B,SCD5,GABRG2,SELL,COL4A5,JAG2,XPR1,PPP2R3A,ITGA2B,NRP2,CD109,FOXP2,IRF2BPL,MDM1,BMP7,GALNS,GTF2F2,ARVCF,ALDH7A1,CLIP2,TLE6,DLGAP1,HMMR,SUN2,FBLN5,RAB3B,AMFR,ASPM,RC3H2,MAML2,COL7A1,CAPNS1,PELI3,BBS2,TXNDC11,SPAG1,PRDX4,ARHGAP24,ENDOD1,SERPINA1,FAT4,FIBCD1,TMC5,CDCA7L,UBE2D2,PGRMC1,CLIP4,FAM117A,UACA,ARRB1,SH3BGRL2,PKD2,GRAMD1C,SOX8,ATP6V1C1,TBC1D4,HIPK3,ZBTB33,ARHGEF4,GOLGB1 |
| 4.138e-02 | -3.19 | PDGF | smart domains | SM00141 | 9 | 4 | 9131 | 1455 |
PDGFA,PGF,PDGFC,PDGFB |
| 4.151e-02 | -3.18 | bone-chordoma | COSMIC cancer mutations | bone-chordoma | 14 | 5 | 17775 | 2585 |
SS18,IDH1,EGFR,PIK3CA,TP53 |
| 4.151e-02 | -3.18 | conjunctiva | COSMIC cancer mutations | conjunctiva | 14 | 5 | 17775 | 2585 |
CTNNB1,IDH1,GNA11,EGFR,TP53 |
| 4.151e-02 | -3.18 | endometriosis | COSMIC cancer mutations | endometriosis | 14 | 5 | 17775 | 2585 |
CTNNB1,AKT1,PTEN,PIK3CA,TP53 |
| 4.151e-02 | -3.18 | urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma | 14 | 5 | 17775 | 2585 |
CTNNB1,PTEN,MSH6,PIK3CA,TP53 |
| 4.151e-02 | -3.18 | large_intestine-rectum-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-rectum-adenoma-tubulovillous | 14 | 5 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 4.151e-02 | -3.18 | in_situ_neoplasm | COSMIC cancer mutations | in_situ_neoplasm | 14 | 5 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 4.151e-02 | -3.18 | large_intestine-rectum-adenoma-tubular | COSMIC cancer mutations | large_intestine-rectum-adenoma-tubular | 14 | 5 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,PIK3R1,PIK3CA |
| 4.151e-02 | -3.18 | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-virilizing_syndrome_producing | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-virilizing_syndrome_producing | 14 | 5 | 17775 | 2585 |
CACHD1,VASP,CTNNB1,MKRN3,TP53 |
| 4.157e-02 | -3.18 | BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_DN | MSigDB lists | BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_DN | 38 | 10 | 17758 | 2588 |
HES1,RABEP2,PLSCR1,CKAP2,INPP5D,SORL1,ASAH1,MOXD1,BMP2K,DUSP1 |
| 4.157e-02 | -3.18 | PID_RAC1_REG_PATHWAY | MSigDB lists | PID_RAC1_REG_PATHWAY | 38 | 10 | 17758 | 2588 |
RASGRF1,ARHGEF7,RALBP1,EPS8,SPATA13,RACGAP1,TIAM1,ABR,DEF6,NGEF |
| 4.161e-02 | -3.18 | CTGYNNCTYTAA_UNKNOWN | MSigDB lists | CTGYNNCTYTAA_UNKNOWN | 81 | 18 | 17758 | 2588 |
ZNF462,INPPL1,CERCAM,FXYD3,OSR2,EPHA1,LDB2,KTN1,NRP2,MECOM,ITGA3,PELI2,OTUB2,DAB2IP,DLG3,BTBD3,NRGN,NR3C2 |
| 4.166e-02 | -3.18 | YBX1 (Y box binding protein 1) | protein interactions | 4904 | 165 | 35 | 16036 | 2547 |
SUZ12,RPS6KA1,CUL4B,HABP4,TP53,FLOT1,CUL1,FBXO6,BARD1,ICAM1,PCNA,PSMC2,TFAP2A,ACTA2,IFIT1,HLA-C,LMAN1,TUBA4A,SIRT1,PSMB4,AKT1,CALM1,SPRTN,CBX6,AGO4,IGSF8,IFIT3,PSMA4,MAP2,AURKA,ARRB1,SRSF9,RPS6KA3,IRF1,RAD21 |
| 4.168e-02 | -3.18 | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | MSigDB lists | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | 115 | 24 | 17758 | 2588 |
DDX58,MX1,LTBP1,CDK17,NF2,SERPINE2,XYLT1,ARL4C,EMP3,ARHGDIB,TGFBR1,IL13RA1,RAB6A,DUSP4,MAP1B,DPYSL3,PTGS2,STX10,PLK2,CALD1,AOX1,SORL1,APOBEC3G,IFI6 |
| 4.172e-02 | -3.18 | human chr7p22.3 | chromosome location | human chr7p22.3 | 31 | 7 | 26250 | 2805 |
SNX8,SUN1,BRAT1,GPER1,MICALL2,FAM20C,IQCE |
| 4.177e-02 | -3.18 | Regulation of Actin Cytoskeleton | WikiPathways | WP51 | 145 | 32 | 4455 | 729 |
PPP1R12A,SSH1,ARHGEF7,IQGAP1,RASSF7,MAPK4,MRAS,NCKAP1,PDGFB,PDGFA,PAK6,RAC2,PAK2,PIK3CA,PIK3CD,F2R,SSH3,RHOA,PIK3R1,PIP4K2C,EZR,CYFIP2,BCAR1,EGFR,ARHGAP35,FGFR2,LIMK1,MYLK,FGF18,PIK3C2B,FGD1,ARHGEF4 |
| 4.178e-02 | -3.18 | GCM_MSN | MSigDB lists | GCM_MSN | 28 | 8 | 17758 | 2588 |
RHOA,DRAP1,PSME1,ARHGDIB,ARHGAP4,PCBP1,TRAM1,ABCC1 |
| 4.178e-02 | -3.18 | MODULE_303 | MSigDB lists | MODULE_303 | 28 | 8 | 17758 | 2588 |
PLK1,NT5C2,AKT1,NEK2,BUB1,PKN1,MAP3K7,CDK1 |
| 4.178e-02 | -3.18 | CHUANG_OXIDATIVE_STRESS_RESPONSE_UP | MSigDB lists | CHUANG_OXIDATIVE_STRESS_RESPONSE_UP | 28 | 8 | 17758 | 2588 |
NQO1,PSMD3,SLC35B3,FDXR,GDF15,EPS8L2,CYP1B1,FAS |
| 4.178e-02 | -3.18 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6 | 28 | 8 | 17758 | 2588 |
MCTP1,RBM24,AOX1,CCDC68,SYTL4,RAB27B,LOXL1,PROM2 |
| 4.178e-02 | -3.18 | GNF2_MSH2 | MSigDB lists | GNF2_MSH2 | 28 | 8 | 17758 | 2588 |
TOP2A,PCNA,NDC80,MSH2,USP1,FANCI,MSH6,SMC4 |
| 4.184e-02 | -3.17 | SABATES_COLORECTAL_ADENOMA_SIZE_DN | MSigDB lists | SABATES_COLORECTAL_ADENOMA_SIZE_DN | 14 | 5 | 17758 | 2588 |
MAOA,C2orf72,PDE4D,RCAN3,GNPTAB |
| 4.184e-02 | -3.17 | GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3 | MSigDB lists | GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3 | 14 | 5 | 17758 | 2588 |
IRF7,IFITM3,IFI6,STAT1,IRF1 |
| 4.184e-02 | -3.17 | GLUTAMINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS | MSigDB lists | GLUTAMINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS | 14 | 5 | 17758 | 2588 |
DDAH1,GCLM,GAD1,GCLC,ASL |
| 4.184e-02 | -3.17 | APICAL_PLASMA_MEMBRANE | MSigDB lists | APICAL_PLASMA_MEMBRANE | 14 | 5 | 17758 | 2588 |
ATP8B1,SHROOM2,SHROOM3,STX3,SLC46A1 |
| 4.184e-02 | -3.17 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | MSigDB lists | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | 14 | 5 | 17758 | 2588 |
FYN,PLXNA1,SEMA3A,LIMK1,PAK2 |
| 4.184e-02 | -3.17 | KYNG_DNA_DAMAGE_BY_4NQO_OR_GAMMA_RADIATION | MSigDB lists | KYNG_DNA_DAMAGE_BY_4NQO_OR_GAMMA_RADIATION | 14 | 5 | 17758 | 2588 |
EPHA1,LRRFIP2,SERPINE2,EGFR,MTMR10 |
| 4.184e-02 | -3.17 | PROTEIN_PHOSPHATASE_TYPE_2A_REGULATOR_ACTIVITY | MSigDB lists | PROTEIN_PHOSPHATASE_TYPE_2A_REGULATOR_ACTIVITY | 14 | 5 | 17758 | 2588 |
PPP2R5A,PPME1,PPP2R5D,PPP2R4,PPP2R3A |
| 4.184e-02 | -3.17 | chr4q34 | MSigDB lists | chr4q34 | 14 | 5 | 17758 | 2588 |
FBXO8,IRF2,CASP3,SPCS3,NEIL3 |
| 4.184e-02 | -3.17 | STEINER_ERYTHROCYTE_MEMBRANE_GENES | MSigDB lists | STEINER_ERYTHROCYTE_MEMBRANE_GENES | 14 | 5 | 17758 | 2588 |
ANK1,ADD3,ERMAP,ADD1,SPTB |
| 4.184e-02 | -3.17 | REGULATION_OF_CELL_MORPHOGENESIS | MSigDB lists | REGULATION_OF_CELL_MORPHOGENESIS | 14 | 5 | 17758 | 2588 |
FGD6,TAOK2,ARAP3,ARAP1,FGD1 |
| 4.184e-02 | -3.17 | DYSTROPHIN_ASSOCIATED_GLYCOPROTEIN_COMPLEX | MSigDB lists | DYSTROPHIN_ASSOCIATED_GLYCOPROTEIN_COMPLEX | 14 | 5 | 17758 | 2588 |
SGCE,SNTB1,SGCB,SNTB2,MAGEE1 |
| 4.184e-02 | -3.17 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | MSigDB lists | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | 14 | 5 | 17758 | 2588 |
B4GALT3,B4GALT4,MGAT4A,MGAT5,MGAT4B |
| 4.184e-02 | -3.17 | SENSORY_ORGAN_DEVELOPMENT | MSigDB lists | SENSORY_ORGAN_DEVELOPMENT | 14 | 5 | 17758 | 2588 |
GAA,SOD1,JAG2,SHROOM2,BAX |
| 4.184e-02 | -3.17 | MATZUK_POST-IMPLANTATION_AND_POST-PARTUM | MSigDB lists | MATZUK_POST-IMPLANTATION_AND_POST-PARTUM | 14 | 5 | 17758 | 2588 |
DAZAP1,FZD4,CSF1,ABCA1,NR2C2 |
| 4.184e-02 | -3.17 | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | MSigDB lists | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | 14 | 5 | 17758 | 2588 |
PRKAA2,CAB39,STRADB,PRKAG2,PRKAA1 |
| 4.184e-02 | -3.17 | CHIN_BREAST_CANCER_COPY_NUMBER_DN | MSigDB lists | CHIN_BREAST_CANCER_COPY_NUMBER_DN | 14 | 5 | 17758 | 2588 |
PDGFRL,CDKN1C,LMAN1,CDH1,CTSB |
| 4.185e-02 | -3.17 | ISG15 (ISG15 ubiquitin-like modifier) | protein interactions | 9636 | 187 | 39 | 16036 | 2547 |
DDX58,ANXA3,UGP2,IQGAP1,HERC5,CCNL1,HDAC6,GSTP1,LMNA,ELF3,PLS3,TOP2A,HELZ2,CTNNB1,PPP1R10,RGS3,CALD1,IFIT1,ERCC2,LGMN,MX1,DDB2,LAP3,DSTN,USP18,PYM1,EZR,PLS1,IFIT3,PKM,VCP,NFIX,STK38,STAT1,SERPINB5,MDH1,PLOD3,HSPB1,CBX4 |
| 4.187e-02 | -3.17 | Activation of Kainate Receptors upon glutamate binding | REACTOME pathways | R-HSA-451326 | 32 | 9 | 8202 | 1235 |
CALM2,GNB5,GRIK2,CALM1,DLG1,CALM3,DLG3,PLCB2,GNB2 |
| 4.190e-02 | -3.17 | KEGG_RENAL_CELL_CARCINOMA | MSigDB lists | KEGG_RENAL_CELL_CARCINOMA | 70 | 16 | 17758 | 2588 |
TCEB2,AKT1,EPAS1,PIK3R1,PDGFB,ETS1,PAK6,PGF,PAK2,PIK3CA,PIK3CD,ARNT2,EGLN3,GAB1,ARNT,EGLN1 |
| 4.191e-02 | -3.17 | Class I PI3K signaling events | Pathway Interaction DB | pi3kcipathway | 41 | 14 | 2227 | 480 |
PLCG1,RHOA,FYN,INPPL1,ARAP3,PTEN,ARHGEF7,PIK3R1,PLCG2,PIK3CA,SGK1,YES1,ARF6,TIAM1 |
| 4.192e-02 | -3.17 | secretory granule membrane | cellular component | GO:0030667 | 75 | 17 | 17570 | 2579 |
LAMP2,SUN1,RAB3B,CD63,ATP8A1,ATP8B3,SYTL4,ITGA2B,CD46,ITPR1,CD9,RAB27B,CPE,FLOT2,MYRIP,TMED2,LAMP3 |
| 4.194e-02 | -3.17 | Fc gamma R-mediated phagocytosis | KEGG pathways | hsa04666 | 92 | 21 | 6908 | 1076 |
BIN1,PLA2G4A,WASF3,INPPL1,AKT1,INPP5D,PIK3R1,PLD2,PLCG1,RAC2,VASP,LIMK1,PLPP3,PLCG2,PIK3CA,DNM2,PLD1,PIK3CD,ARF6,ARPC2,SYK |
| 4.194e-02 | -3.17 | Fc gamma R-mediated phagocytosis | KEGG pathways | ko04666 | 92 | 21 | 6908 | 1076 |
BIN1,PLA2G4A,WASF3,INPPL1,AKT1,INPP5D,PIK3R1,PLD2,PLCG1,RAC2,VASP,LIMK1,PLPP3,PLCG2,PIK3CA,DNM2,PLD1,PIK3CD,ARF6,ARPC2,SYK |
| 4.195e-02 | -3.17 | protein modification by small protein conjugation or removal | biological process | GO:0070647 | 843 | 144 | 16441 | 2455 |
CCNC,UNKL,TRIM2,TRIM24,TRIM5,CUL4B,XIAP,FBXO2,CUL1,UBE2Z,UBE2Q1,PSME1,HDAC6,PJA2,BARD1,SPSB1,TRIM68,PSMD1,NUP210,UBE2T,MKRN3,PSMC2,MARCH2,PLK1,TRIM8,FBXL16,ASXL1,ITCH,USP18,RNF11,RNF165,CCNF,RNF19B,VCP,PIAS3,TRIM9,TRAF5,PSMC1,ASB9,PSMD7,ZNRF3,HERC6,SH3RF2,MARCH8,OTUD1,UBE2Q2,ZNRF2,FBXO7,FBXL14,USP1,USP38,ZRANB1,MYLIP,NUP85,PSMA5,SOCS5,DDB2,USP31,SHARPIN,KBTBD8,PSMA4,FBXO10,G2E3,PELI2,KBTBD2,PIAS2,DCUN1D1,YOD1,IFIH1,NUP58,RNF146,RUSC1,USP43,RAD21,FBXW5,LMO7,PAX6,PSME2,SUZ12,WDTC1,RNF182,KBTBD11,RNF220,SP100,RNF169,SIRT1,TCEB2,AKT1,CDC20,PRKCQ,ASB13,CBL,SOCS3,PSMD3,WWTR1,PEX2,AREL1,CBX4,ZC3HC1,OTUD5,PINK1,KLHL13,TRAF2,DCAF7,SHPRH,CDCA3,HERC5,PSMD10,CBLL1,FBXO6,TSPAN17,WWP2,DTX3L,RNF128,IRAK1,UBE2J1,TRIM3,TRIM21,WWP1,RAG1,TRIM62,DCAF6,PSMB4,AMFR,NUB1,RC3H2,UBE2A,FBXO9,UBAC1,PELI3,NEURL1B,USP6,DCAF10,KLHL2,ATXN7L3,TRIM69,DTX4,UBE2D2,ARRB1,OTUB2,NUP37,UBE2C,USP16,PHC1 |
| 4.204e-02 | -3.17 | LU_EZH2_TARGETS_UP | MSigDB lists | LU_EZH2_TARGETS_UP | 270 | 50 | 17758 | 2588 |
MFSD3,SIGIRR,AVPI1,LMTK3,TMEM217,PLEKHJ1,ZCCHC24,HABP4,SDC4,BIK,SOD2,FLOT1,NES,F11R,NENF,ISOC2,HDGFRP2,S100A2,TSPAN17,LMNA,IER3,ARTN,PFKL,MAPK11,IFIT1,S100A13,S100A6,CYP1B1,PAQR7,PODXL2,TCEB2,PRSS23,TESK1,MAPKAPK3,S100A4,SHARPIN,IFIT3,GNA11,TYSND1,PRDX4,TRIM47,CASP7,NGFRAP1,TMEM30A,HAGHL,TRIOBP,PRKCDBP,HDAC1,FAM195A,IRF7 |
| 4.206e-02 | -3.17 | MCBRYAN_PUBERTAL_BREAST_3_4WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_3_4WK_DN | 33 | 9 | 17758 | 2588 |
CD99,PRKAG2,MBP,ADCK3,BCL6,TCF7,NFKB2,IDH1,CTH |
| 4.206e-02 | -3.17 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_DN | 33 | 9 | 17758 | 2588 |
FAM171B,MTM1,DYRK3,RPS6KA2,RNF128,AKR1B1,WHSC1,WDR62,NMT2 |
| 4.206e-02 | -3.17 | PID_NCADHERIN_PATHWAY | MSigDB lists | PID_NCADHERIN_PATHWAY | 33 | 9 | 17758 | 2588 |
KIF5B,PLCG1,RHOA,CTNNB1,PIK3R1,PIK3CA,CTNND1,CTTN,CAMK2G |
| 4.206e-02 | -3.17 | MICROTUBULE_BINDING | MSigDB lists | MICROTUBULE_BINDING | 33 | 9 | 17758 | 2588 |
KIF5B,SUN2,HTT,UXT,TUBGCP6,NDE1,CCDC88A,ATG4A,ATG4D |
| 4.206e-02 | -3.17 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP | 33 | 9 | 17758 | 2588 |
SOAT1,NOV,OXCT1,KCNN4,CALCRL,NR4A2,DSE,FAM46C,AHR |
| 4.206e-02 | -3.17 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP | 33 | 9 | 17758 | 2588 |
KLF2,CD55,RGMB,ETV5,OSGIN2,RHPN2,SNX16,CCDC82,SPRY4 |
| 4.206e-02 | -3.17 | MODULE_522 | MSigDB lists | MODULE_522 | 33 | 9 | 17758 | 2588 |
TXN,SEC61B,IL15RA,LGALS3,TRIP10,DNAJC3,GRK6,NFKB2,SPSB1 |
| 4.213e-02 | -3.17 | cNMP-bd-like | interpro domains | IPR018490 | 38 | 10 | 18293 | 2672 |
POPDC3,BVES,RAPGEF2,PNPLA6,PRKG1,CNNM4,PRKAR2B,CNGA1,PRKAR1A,HCN3 |
| 4.219e-02 | -3.17 | FN3_dom | interpro domains | IPR003961 | 209 | 40 | 18293 | 2672 |
EPHA4,IL27RA,IL13RA1,MERTK,IL22RA1,NEO1,PHYHIP,IGF1R,IGSF9,VASN,FLRT3,IL6ST,ANKFN1,IL31RA,KIAA0319,SORL1,EPHB4,NCAM1,IL10RB,SNED1,IGDCC4,PTPRU,VWA1,COL7A1,EPHA1,FNDC3A,MYOM1,LEPR,COL12A1,PTPRF,TRIM9,EPHA10,INSR,PTPRJ,AXL,MYLK,OSMR,L1CAM,LIFR,POMGNT2 |
| 4.221e-02 | -3.17 | P-type_ATPase_N | interpro domains | IPR032631 | 14 | 5 | 18293 | 2672 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 4.221e-02 | -3.17 | RasGAP_CS | interpro domains | IPR023152 | 14 | 5 | 18293 | 2672 |
DAB2IP,IQGAP3,IQGAP1,RASA2,RASA1 |
| 4.221e-02 | -3.17 | TF_A-like/BEX-like | interpro domains | IPR021156 | 14 | 5 | 18293 | 2672 |
TCEAL8,NGFRAP1,BEX2,TCEAL4,WBP5 |
| 4.221e-02 | -3.17 | P-type_ATPase_IV | interpro domains | IPR006539 | 14 | 5 | 18293 | 2672 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 4.221e-02 | -3.17 | P_typ_ATPase_c | interpro domains | IPR032630 | 14 | 5 | 18293 | 2672 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 4.221e-02 | -3.17 | Cyt_B5-like_heme/steroid-bd | interpro domains | IPR001199 | 14 | 5 | 18293 | 2672 |
FADS2,NENF,FA2H,CYB5A,PGRMC1 |
| 4.224e-02 | -3.16 | human chr12q23.2 | chromosome location | human chr12q23.2 | 13 | 4 | 26250 | 2805 |
NUP37,ARL1,GNPTAB,DRAM1 |
| 4.231e-02 | -3.16 | coenzyme binding | molecular function | GO:0050662 | 182 | 36 | 16491 | 2452 |
ALDH6A1,CRYM,AIFM2,SPR,ALDH1A3,AOX1,ECI2,HMGCL,CRY2,AHCY,ACOX2,ACAD8,SIRT1,SOAT1,ACBD5,PRODH,AGPS,ACBD3,GCLC,OGDHL,IDH1,TP53I3,POR,DUOX1,MARC1,ACADSB,ACAD10,DBI,MAOA,DHTKD1,MDH1,ACADM,AIFM3,CTBP1,ACOT7,XDH |
| 4.241e-02 | -3.16 | EPHB-mediated forward signaling | REACTOME pathways | R-HSA-3928662 | 42 | 11 | 8202 | 1235 |
FYN,ARHGEF28,RHOA,LIMK1,GRIN1,EPHB4,YES1,ARPC2,TIAM1,EFNB1,RASA1 |
| 4.241e-02 | -3.16 | Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | REACTOME pathways | R-HSA-381676 | 42 | 11 | 8202 | 1235 |
GNAS,GNB5,IQGAP1,ITPR1,KCNS3,PRKAR2B,ITPR2,ITPR3,PRKACA,GNB2,PRKAR1A |
| 4.241e-02 | -3.16 | Signaling by FGFR1 fusion mutants | REACTOME pathways | R-HSA-1839117 | 18 | 6 | 8202 | 1235 |
TRIM24,CNTRL,FGFR1OP2,PIK3R1,STAT1,PIK3CA |
| 4.241e-02 | -3.16 | Pre-NOTCH Processing in Golgi | REACTOME pathways | R-HSA-1912420 | 18 | 6 | 8202 | 1235 |
NOTCH3,RAB6A,NOTCH2,LFNG,TMED2,FURIN |
| 4.241e-02 | -3.16 | Miscellaneous transport and binding events | REACTOME pathways | R-HSA-5223345 | 18 | 6 | 8202 | 1235 |
ADD3,CTNS,ADD1,DMTN,NIPA1,MRS2 |
| 4.241e-02 | -3.16 | Defects in vitamin and cofactor metabolism | REACTOME pathways | R-HSA-3296482 | 18 | 6 | 8202 | 1235 |
PCCB,ACACB,TCN2,MCCC2,MCCC1,MMADHC |
| 4.245e-02 | -3.16 | SCF ubiquitin ligase complex | cellular component | GO:0019005 | 43 | 11 | 17570 | 2579 |
FBXL16,FBXL14,FBXO2,TRIM21,FBXO9,CUL1,FBXO44,FBXO6,CCNF,FBXO27,FBXW5 |
| 4.251e-02 | -3.16 | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | MSigDB lists | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | 156 | 31 | 17758 | 2588 |
SUSD3,SYPL1,KLF2,CD55,CXXC5,BLVRB,ARHGDIB,SNN,CYFIP2,TRIB2,ETS1,TNFRSF19,SH3KBP1,LCP1,RASGRP2,CDKN2C,FAM111A,BTG1,SESN3,BANK1,RABEP2,CDK19,FRYL,CD22,FCHO1,RIN3,ITPR1,CNOT6L,RBM43,SERPINB1,RASGRP1 |
| 4.254e-02 | -3.16 | CYP3A4 (cytochrome P450, family 3, subfamily A, polypeptide 4) | protein interactions | 1576 | 13 | 5 | 16036 | 2547 |
PRKACA,POR,AMFR,CYB5A,PGRMC1 |
| 4.254e-02 | -3.16 | WDR45B (WD repeat domain 45B) | protein interactions | 56270 | 13 | 5 | 16036 | 2547 |
GAS2L1,AK4,RCN1,ARRDC1,SPA17 |
| 4.254e-02 | -3.16 | HS2ST1 (heparan sulfate 2-O-sulfotransferase 1) | protein interactions | 9653 | 13 | 5 | 16036 | 2547 |
P2RX4,TGOLN2,TSPAN17,HLA-A,CKAP4 |
| 4.254e-02 | -3.16 | UPK3BL (uroplakin 3B-like) | protein interactions | 100134938 | 13 | 5 | 16036 | 2547 |
FAM189A2,TMEM30A,TSPAN17,SPINT2,MCOLN3 |
| 4.254e-02 | -3.16 | SPTLC1 (serine palmitoyltransferase, long chain base subunit 1) | protein interactions | 10558 | 13 | 5 | 16036 | 2547 |
FBXO6,SPTLC2,ABCA1,EGFR,RGS20 |
| 4.254e-02 | -3.16 | GRAMD1A (GRAM domain containing 1A) | protein interactions | 57655 | 13 | 5 | 16036 | 2547 |
GMCL1,ACVR1,FAM189A2,TMEM30A,MCOLN3 |
| 4.254e-02 | -3.16 | DLGAP3 (discs, large (Drosophila) homolog-associated protein 3) | protein interactions | 58512 | 13 | 5 | 16036 | 2547 |
DLGAP1,CUL1,DLG3,CUL4B,DLG1 |
| 4.254e-02 | -3.16 | PHLPP2 (PH domain and leucine rich repeat protein phosphatase 2) | protein interactions | 23035 | 13 | 5 | 16036 | 2547 |
EZR,VAT1,USP1,PHLPP1,SLC9A3R2 |
| 4.254e-02 | -3.16 | Pafah1b1 (platelet-activating factor acetylhydrolase, isoform 1b, subunit 1) | protein interactions | 18472 | 13 | 5 | 16036 | 2547 |
PPP1CA,PAFAH1B3,NDE1,CALD1,PLS3 |
| 4.254e-02 | -3.16 | CAMKK1 (calcium/calmodulin-dependent protein kinase kinase 1, alpha) | protein interactions | 84254 | 13 | 5 | 16036 | 2547 |
SGK1,CAMK1D,AKT1,CALM1,PRKAA1 |
| 4.254e-02 | -3.16 | PPP2R3A (protein phosphatase 2, regulatory subunit B'', alpha) | protein interactions | 5523 | 13 | 5 | 16036 | 2547 |
CDK17,RBL1,PPP2R4,EGFR,PPP2R3A |
| 4.254e-02 | -3.16 | POLM (polymerase (DNA directed), mu) | protein interactions | 27434 | 13 | 5 | 16036 | 2547 |
PCNA,PTEN,UBE2C,PTTG1,UBE2D2 |
| 4.254e-02 | -3.16 | BACH2 (BTB and CNC homology 1, basic leucine zipper transcription factor 2) | protein interactions | 60468 | 13 | 5 | 16036 | 2547 |
ARRB1,NFE2L3,MAFF,BCL6,NFE2L1 |
| 4.254e-02 | -3.16 | HLA-DRB5 (major histocompatibility complex, class II, DR beta 5) | protein interactions | 3127 | 13 | 5 | 16036 | 2547 |
ATP1B1,PKM,HLA-A,ANXA11,STAT1 |
| 4.254e-02 | -3.16 | NEU2 (sialidase 2 (cytosolic sialidase)) | protein interactions | 4759 | 13 | 5 | 16036 | 2547 |
TFAP4,FAM217B,ZWINT,NOTCH3,PEX5 |
| 4.254e-02 | -3.16 | TAP2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)) | protein interactions | 6891 | 13 | 5 | 16036 | 2547 |
TAPBP,HLA-C,HLA-E,HLA-A,TAP1 |
| 4.272e-02 | -3.15 | V$POU3F2_02 | MSigDB lists | V$POU3F2_02 | 252 | 47 | 17758 | 2588 |
PNISR,FRMD4A,CHCHD7,STRN4,XIAP,GABRG2,PBX3,DUSP5,HPCAL4,TEAD3,LMNA,GBX2,NEO1,HDAC9,PDGFA,FOXP2,MDM1,ADD3,IRAK1,PTEN,CYR61,XYLT2,LMO4,LHX6,MITF,DIXDC1,SCN2A,MYT1,DGKG,SMARCA2,ING1,CXXC5,ASXL1,PIK3R1,OGDHL,TFAP2C,TMTC2,NFIX,MAGED2,TAPBP,NEIL3,PAPD5,SP6,MAL2,SEMA3A,HS6ST3,NXT2 |
| 4.276e-02 | -3.15 | extracellular matrix | cellular component | GO:0031012 | 422 | 75 | 17570 | 2579 |
LTBP1,AGRN,HSPG2,P3H2,LMCD1,COL18A1,LTBP3,NOV,TGFBR3,MUC4,CTGF,NPNT,DLG1,NTN4,TINAGL1,LOXL1,OLFML2A,SOD1,TIMP2,COL6A2,LOXL2,ERBB2IP,DAG1,COL12A1,MMP17,BMP1,ADAMTS14,MAMDC2,COL9A3,CTHRC1,HSP90B1,PCOLCE,LGALS3,SERPINE2,HAPLN3,ITGA6,COL4A5,SLC1A3,FBLN1,ADAMTSL4,LGALS3BP,CALR,TIMP1,CYR61,FLRT3,GPC3,FRAS1,BMP7,CST3,COL6A1,WNT3A,NTN1,CTSD,CRTAP,ADAMTS2,CASK,FBLN5,PLSCR1,WNT10B,CRIP2,VWA1,COL7A1,ILK,PKM,CRISPLD2,GPLD1,MMP15,TIMP3,SERPINA1,FGFR2,MATN2,EGFL7,LTBP2,COL16A1,ADAMTS16 |
| 4.282e-02 | -3.15 | cellular response to acid chemical | biological process | GO:0071229 | 164 | 33 | 16441 | 2455 |
PRKAA2,CPEB4,SOX9,RET,PRKAA1,BCL2L1,CCNB1,PDGFB,CAPN2,COL6A1,WNT3A,PDGFC,SHMT1,AKT1,WNT10B,FZD4,YES1,PDK3,FZD7,EGFR,GNAS,TBX1,PTK7,SH3BP4,DGAT2,E2F1,PKD2,OSR1,RARG,ABCA1,COL16A1,PHC1,RRAGD |
| 4.283e-02 | -3.15 | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP | MSigDB lists | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP | 162 | 32 | 17758 | 2588 |
TRAPPC10,C6orf106,ERBB2,SBF1,PDXDC1,ABCD4,RABEP2,LLGL2,RGS3,DDHD2,PHTF1,PDIA6,LRIF1,NUP85,MED22,MLEC,COL6A2,TAF5,PRSS23,TESK1,MRS2,ICMT,CASP4,ATP10D,RASGRP2,ZFP30,WDR19,ABCB1,TLE1,RGS14,CBX7,NR3C2 |
| 4.283e-02 | -3.15 | PENG_GLUCOSE_DEPRIVATION_DN | MSigDB lists | PENG_GLUCOSE_DEPRIVATION_DN | 162 | 32 | 17758 | 2588 |
GMPR,FANCI,PICK1,DAPK2,ATP6V0B,RB1,WEE1,ARTN,DPYSL2,PAPSS1,RRBP1,MSH2,TMBIM6,PSMA5,SMC4,MICB,GTF2A2,ILK,KIF11,SLC25A5,H2AFV,CDK1,ARF4,HLF,PPP2R5A,RAB31,BMP1,E2F1,AURKA,TRAF5,ESPL1,EHD1 |
| 4.283e-02 | -3.15 | GSE22045_TREG_VS_TCONV_UP | MSigDB lists | GSE22045_TREG_VS_TCONV_UP | 162 | 32 | 17758 | 2588 |
COL9A3,FAM160B1,MAN1A2,SDC4,MTL5,ABCG2,JAG2,VASH1,IL18R1,CYP26A1,CORO1B,RAC2,NEK2,F2R,NAGA,PPIF,CASK,KIAA1841,PBK,DENND1B,HTATIP2,TTC7A,ATP8B3,PCTP,KIF11,CD83,COL13A1,SIPA1L1,SLC4A3,CENPE,HS3ST3B1,NCAPG2 |
| 4.297e-02 | -3.15 | positive regulation of nervous system development | biological process | GO:0051962 | 409 | 74 | 16441 | 2455 |
FOXO6,AGRN,EPHA4,RET,CAMK1D,GRM5,TP73,CTNNB1,CDKL5,IL6ST,BCL6,SMO,DAB2IP,PACSIN1,TIAM1,TIMP2,CDC20,CLSTN1,RHEB,ARHGAP35,IRX3,DPYSL3,FYN,GPRC5B,BHLHB9,PTK7,LIMK1,EFNA5,NRG1,ITPKA,RGS14,COBL,GRN,BIN1,WASF3,SERPINE2,ETV5,CRABP2,SRPX2,ADGRB2,BMP2,ITGA3,GATA2,MEGF8,FLRT3,BMP7,PRKCI,TNFRSF12A,NPTN,WNT3A,NTN1,TLE6,RIMS2,FAM134C,TGIF1,HES1,RHOA,MMD,RAPGEF2,ASPM,HMG20B,KIF20B,ILK,MAP1B,SEMA4D,CSF1,TMEM30A,GPER1,SOX8,ARSB,SHOX2,SEMA3A,L1CAM,FOXA1 |
| 4.298e-02 | -3.15 | positive regulation of neuron differentiation | biological process | GO:0045666 | 276 | 52 | 16441 | 2455 |
GRN,FOXO6,SERPINE2,RET,EPHA4,ETV5,CAMK1D,CRABP2,BMP2,ITGA3,GATA2,CDKL5,MEGF8,BMP7,BCL6,PRKCI,TNFRSF12A,DAB2IP,NPTN,PACSIN1,WNT3A,NTN1,TIAM1,RIMS2,TLE6,FAM134C,TGIF1,RHOA,TIMP2,MMD,RAPGEF2,HMG20B,ILK,MAP1B,ARHGAP35,IRX3,DPYSL3,FYN,GPRC5B,SEMA4D,BHLHB9,PTK7,LIMK1,TMEM30A,EFNA5,NRG1,ITPKA,ARSB,SHOX2,COBL,L1CAM,FOXA1 |
| 4.298e-02 | -3.15 | PSMB7 (proteasome subunit beta 7) | protein interactions | 5695 | 80 | 19 | 16036 | 2547 |
PLK1,PSMB4,PSME2,CAST,AMFR,PSMD7,PYGL,PSME1,PSMA4,RAD23A,KIF5B,PSMD1,HTT,PSMD3,FBXO7,PSMC2,AURKA,PSMC1,PSMA5 |
| 4.298e-02 | -3.15 | VASP (vasodilator-stimulated phosphoprotein) | protein interactions | 7408 | 80 | 19 | 16036 | 2547 |
ERMAP,PLSCR1,NR4A1,LRP4,CUL4B,SAT1,TP53,CYFIP2,PRKACA,WWP2,TRIM9,ZYX,VASP,UAP1,IRAK1,PRKG1,ATP6V1C1,SRSF9,PSMA5 |
| 4.300e-02 | -3.15 | compact myelin | cellular component | GO:0043218 | 14 | 5 | 17570 | 2579 |
AKR1B1,MPP5,MBP,PTEN,PRKCI |
| 4.301e-02 | -3.15 | Apoptosis | WikiPathways | WP254 | 83 | 20 | 4455 | 729 |
CASP3,AKT1,NFKBIE,TRAF2,PIK3R1,CASP9,TP53,BNIP3L,XIAP,BCL2L1,CASP4,FAS,TP73,CASP7,IGF1R,NFKBIA,BAX,IRF2,IRF7,IRF1 |
| 4.302e-02 | -3.15 | embryonic organ morphogenesis | biological process | GO:0048562 | 282 | 53 | 16441 | 2455 |
CTHRC1,ACVR1,RUNX2,USH1C,GRHL2,HSPG2,HOXB7,SOX9,GATA3,TGFBR1,OSR2,NCKAP1,STIL,HOXB2,SIX4,FZD6,GBX2,SETDB2,CTNNB1,GATA2,BMP7,MEGF8,ALDH1A3,SMO,DLG1,TFAP2A,TWIST1,WNT3A,NTN1,GFI1,SPRY2,DVL2,MDFI,HES1,SPEF2,SOD1,SCRIB,PRKRA,NPHP3,ABR,GNAS,FGFR2,TBX1,PTK7,LRIG1,TBX18,NR4A3,PKD2,EFNA1,OSR1,FZD5,SHOX2,RARG |
| 4.304e-02 | -3.15 | Etoposide Action Pathway | SMPDB pathways | SMP00442 | 18 | 7 | 978 | 190 |
TOP2A,DNAJB11,PTGS2,PDIA6,ERP29,ABCB1,PDIA4 |
| 4.304e-02 | -3.15 | Etoposide Metabolism Pathway | SMPDB pathways | SMP00601 | 18 | 7 | 978 | 190 |
TOP2A,DNAJB11,PTGS2,PDIA6,ERP29,ABCB1,PDIA4 |
| 4.307e-02 | -3.14 | uveal_tract | COSMIC cancer mutations | uveal_tract | 603 | 103 | 17775 | 2585 |
NF2,REPS2,RET,CUL4B,FHDC1,TP53,ERBB2,PKP2,GRK6,SYTL4,CCNL1,HDAC6,SNX9,FLT3,GNB2,EPS8L2,CHPF,ABCD4,EPCAM,LRRC45,CTNNB1,CDH1,MITF,SMO,PIK3CA,CPE,NEB,CD55,AKT1,LAP3,PYGO1,ITPR3,IDH1,SESN1,CLCN2,TRUB1,ANKRD10,PLEKHG6,FAM177A1,SHROOM3,PLK2,PTK7,RAB11FIP1,BMP1,PLXND1,CHPT1,CBX4,ZNF720,RECQL,GALK1,TRAF2,SDC4,GDF15,NDUFA4,INTS8,PDXDC1,IL22RA1,COX7A2,CD109,IRF2BPL,SNX13,RB1,PTEN,MSH2,PCYOX1,ACTA2,MAPK11,IQGAP3,CITED2,EEF1D,MSH6,SNX7,SPATA20,CHSY3,CYP26B1,PMPCB,CASK,PCDH1,PIK3R1,LRRC66,PARP4,PRICKLE1,ZSCAN12,ATP8B3,FAM73B,NPHP3,MEST,GNA11,EGFR,RASA1,GNAS,CNTNAP1,SLCO4A1,HCP5,FAT4,FGFR2,PRCP,CTSA,CDAN1,CBX5,JAK3,ARHGEF4,TLL2 |
| 4.310e-02 | -3.14 | V$MYOGENIN_Q6 | MSigDB lists | V$MYOGENIN_Q6 | 240 | 45 | 17758 | 2588 |
EMX1,FBLIM1,SORT1,ZCCHC24,ITGA6,XYLT1,WDTC1,PKN1,PRKACA,SPTB,ZFYVE9,CYP26A1,CDKN2C,PAK6,RNF220,STIM1,CABP1,CDH3,IQCD,TRIM62,TPCN1,IGSF3,EPB41L5,PCGF5,TGIF1,ELK3,TRIM8,KCNIP3,WNT10B,PARD3B,CRIP2,VWA1,TNFAIP8L1,RUNX3,IGSF8,ATP1B1,UNC45B,RNF19B,DDAH1,PTPRJ,AXL,UACA,OSR1,DMPK,DOCK9 |
| 4.310e-02 | -3.14 | RAB3A (RAB3A, member RAS oncogene family) | protein interactions | 5864 | 40 | 11 | 16036 | 2547 |
RAB3B,CASK,AP1M2,TGOLN2,RAB3IP,SYTL4,WDR45B,RIMS2,RAB3IL1,EGFR,RABGGTA |
| 4.310e-02 | -3.14 | MAPK11 (mitogen-activated protein kinase 11) | protein interactions | 5600 | 40 | 11 | 16036 | 2547 |
MAPKAPK2,ELK4,CCND1,MBP,NOXA1,MAPKAPK3,DUSP10,HDAC1,ELK1,PKN1,SOCS3 |
| 4.310e-02 | -3.14 | SP3 (Sp3 transcription factor) | protein interactions | 6670 | 40 | 11 | 16036 | 2547 |
TFAP4,RB1,NKX3-1,PPP2R4,GRIN1,E2F1,TP53,HDAC1,B4GALT4,ZBTB7B,SP4 |
| 4.310e-02 | -3.14 | MOHANKUMAR_TLX1_TARGETS_DN | MSigDB lists | MOHANKUMAR_TLX1_TARGETS_DN | 168 | 33 | 17758 | 2588 |
HLA-F,GALNT12,FXYD3,EPHA4,BIK,IL18,PLAC1,GDF15,FAM198B,CDK14,ARHGAP42,CA2,ARHGEF37,BMP7,STEAP2,SGK1,GAD1,S100A6,IGSF3,RAB3B,C3orf52,ALCAM,STEAP1,MAP1B,DCAF10,AREG,NMI,SERPINB5,MAPK13,PLD1,UNC5B,PKIA,ARHGEF4 |
| 4.314e-02 | -3.14 | response to transition metal nanoparticle | biological process | GO:1990267 | 124 | 26 | 16441 | 2455 |
SOD1,GRIN1,ACO1,P2RX7,GGH,SLC11A2,LOXL2,CCNB1,ICAM1,ATP13A2,FECH,CCND1,NUCB1,PTGS2,CYP1A1,CA2,PTEN,ATP7B,SLC30A6,BAX,TFAP2A,ARSB,LTA4H,S100A13,CYBRD1,HCN3 |
| 4.324e-02 | -3.14 | NUSAP1 (nucleolar and spindle associated protein 1) | protein interactions | 51203 | 26 | 8 | 16036 | 2547 |
CEP70,PPP1R12A,UGP2,PLOD2,PRDX3,C5orf30,CCNF,SLC9A3R2 |
| 4.324e-02 | -3.14 | PDK1 (pyruvate dehydrogenase kinase, isozyme 1) | protein interactions | 5163 | 26 | 8 | 16036 | 2547 |
HLA-B,AKT1,SGK1,PDK3,PKN1,PDHX,EGFR,DLAT |
| 4.324e-02 | -3.14 | GAPVD1 (GTPase activating protein and VPS9 domains 1) | protein interactions | 26130 | 26 | 8 | 16036 | 2547 |
NR3C1,CCDC6,IQGAP1,RASA2,AURKA,CBL,HSPB1,RAD21 |
| 4.324e-02 | -3.14 | NSL1 (NSL1, MIS12 kinetochore complex component) | protein interactions | 25936 | 26 | 8 | 16036 | 2547 |
ZWINT,SPC25,NDC80,NUF2,BUB1,AURKB,CBX5,SGOL1 |
| 4.324e-02 | -3.14 | tetrapyrrole metabolic process | biological process | GO:0033013 | 58 | 14 | 16441 | 2455 |
FECH,CYP1A1,BLVRB,NFE2L1,MMADHC,SLC11A2,EIF2AK1,BLVRA,SLC25A38,RSAD1,SPTB,TCN2,ABCC1,ABCD4 |
| 4.325e-02 | -3.14 | V$HIF1_Q5 | MSigDB lists | V$HIF1_Q5 | 234 | 44 | 17758 | 2588 |
LTBP1,RECQL,DAP,CACNA2D2,IRX4,GRK6,PHLPP1,BAHD1,PDGFB,PRR7,KTN1,HPCAL4,BMP2,WEE1,BHLHE41,BCL6,TWIST1,KLF9,AK3,PIM1,CITED2,BTBD3,TIAM1,NRBF2,TEF,ITCH,PDK3,C15orf39,KDM3A,GOLT1A,PRDX4,PTPRF,PITX2,ONECUT1,PTPRJ,FAM114A1,NXPH4,KLF11,PRIMA1,HMGA1,ATP1B3,ARPC2,AIFM3,USF2 |
| 4.325e-02 | -3.14 | V$S8_01 | MSigDB lists | V$S8_01 | 234 | 44 | 17758 | 2588 |
INPPL1,TRIM24,HOXB7,IRX4,TESK2,OSR2,PRKACA,SYTL2,GRM5,GBX2,NEO1,ARHGEF10L,KCTD15,RALGPS2,CALD1,XYLT2,PPP1R16A,MITF,FOSB,DIXDC1,MYT1,BTBD3,SCN3A,SOCS5,SULF2,RNF11,RGAG1,CYFIP2,LDB2,ITPR3,TMTC2,LCP1,EBF2,ACADSB,HOXA9,BMP1,OVOL1,CTNND1,EFNA5,SH3BGRL2,LEMD1,GEN1,SHOX2,SEMA3A |
| 4.325e-02 | -3.14 | DAZARD_RESPONSE_TO_UV_NHEK_UP | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_UP | 234 | 44 | 17758 | 2588 |
TXN,NF2,IGFBP6,CDKN1C,TUBB4B,SEC61G,CYP2J2,HEXB,APC2,MAP1LC3B,PHLDA1,COX7A2,H1FX,IER3,TYMP,CTGF,CYR61,CDK16,PAIP2B,ZFP36,RANBP1,SGK1,CLDN4,TACSTD2,IGFBP2,ERCC2,CITED2,SULT2B1,HSPA2,TUBA4A,DUSP1,PPIF,CAPNS1,FOS,STK17B,BTG1,NUCB1,PTGS2,STAT6,ITPR1,NR4A2,RCAN2,GEM,TOB1 |
| 4.334e-02 | -3.14 | PECE_MAMMARY_STEM_CELL_DN | MSigDB lists | PECE_MAMMARY_STEM_CELL_DN | 127 | 26 | 17758 | 2588 |
WASF3,PNISR,CNOT8,BTBD19,PDIA3,CTSZ,CCNL1,MAP1LC3B,SLC25A43,RAB2B,RASA1,ANKRD10,KLF12,JAK1,TM9SF2,P4HB,CALD1,IMPAD1,COL6A1,TRPC1,FHL1,FGFR1OP2,RNF146,SNED1,RUSC1,IGDCC4 |
| 4.334e-02 | -3.14 | ACTIN_CYTOSKELETON | MSigDB lists | ACTIN_CYTOSKELETON | 127 | 26 | 17758 | 2588 |
MYL9,BIN1,LASP1,CASK,BMF,SORBS1,IQGAP1,EZR,ANLN,AIF1L,MYOM1,SPTB,DAG1,ABLIM2,KLHL2,TSC1,VASP,CDH1,CORO1C,CAPG,DAPK1,PKD2,ESPN,ARPC2,SHROOM2,NEB |
| 4.335e-02 | -3.14 | KEGG_NON_SMALL_CELL_LUNG_CANCER | MSigDB lists | KEGG_NON_SMALL_CELL_LUNG_CANCER | 54 | 13 | 17758 | 2588 |
CCND1,RB1,PLCG1,AKT1,CASP9,PLCG2,PIK3R1,PIK3CA,E2F1,TP53,ERBB2,PIK3CD,EGFR |
| 4.335e-02 | -3.14 | GNF2_ITGAL | MSigDB lists | GNF2_ITGAL | 54 | 13 | 17758 | 2588 |
DDX58,SUN2,SIGIRR,ARHGEF3,FYN,JAK1,SEMA4D,HLA-F,STK38,ARL4C,BTN3A2,BTN3A1,RASGRP1 |
| 4.335e-02 | -3.14 | MORF_GPX4 | MSigDB lists | MORF_GPX4 | 54 | 13 | 17758 | 2588 |
PSMB4,DDOST,DAP,TMBIM6,GLB1,TECR,MYL12B,BCAP31,GNB2,RHEB,EEF1D,KDELR1,GPX4 |
| 4.335e-02 | -3.14 | trans-Golgi network transport vesicle | cellular component | GO:0030140 | 28 | 8 | 17570 | 2579 |
LDLRAP1,SORT1,SLC2A4,STEAP2,FURIN,TGOLN2,RAB27B,NRGN |
| 4.336e-02 | -3.14 | Activated TLR4 signalling | REACTOME pathways | R-HSA-166054 | 112 | 24 | 8202 | 1235 |
SIGIRR,RIPK2,TAB3,MAPKAPK3,RPS6KA1,CUL1,PELI3,DUSP4,ELK1,FOS,MAPKAPK2,RPS6KA2,IRAK1,PELI2,NFKBIA,UBE2D2,NOD2,IRF7,MAPK11,MAP3K7,MAPK7,NFKB2,PPP2R5D,RPS6KA3 |
| 4.337e-02 | -3.14 | stereocilium | cellular component | GO:0032420 | 38 | 10 | 17570 | 2579 |
DOCK4,TPRN,PROM1,USH1C,MPP1,EPS8,ATP8B1,ESPN,TMC1,PLS3 |
| 4.337e-02 | -3.14 | ErbB signaling pathway | KEGG pathways | ko04012 | 87 | 20 | 6908 | 1076 |
AKT1,PIK3R1,ERBB2,NRG2,CBL,ELK1,EGFR,PAK6,PLCG1,SHC3,AREG,PAK2,PLCG2,PIK3CA,CDKN1B,NRG1,ERBB3,PIK3CD,GAB1,CAMK2G |
| 4.337e-02 | -3.14 | ErbB signaling pathway | KEGG pathways | hsa04012 | 87 | 20 | 6908 | 1076 |
AKT1,PIK3R1,ERBB2,NRG2,CBL,ELK1,EGFR,PAK6,PLCG1,AREG,SHC3,PLCG2,PAK2,PIK3CA,CDKN1B,NRG1,PIK3CD,ERBB3,GAB1,CAMK2G |
| 4.344e-02 | -3.14 | HOEBEKE_LYMPHOID_STEM_CELL_UP | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_UP | 87 | 19 | 17758 | 2588 |
PAPD7,TMEM41B,RUNX3,CCNL1,TRIB2,KDM3A,TNS3,RPS6KA2,MSL1,OSBPL3,TBCD,BCL6,RAB31,PLXND1,KNTC1,TRAF5,COBL,ABCA1,SCN3A |
| 4.346e-02 | -3.14 | TCCAGAT,MIR-516-5P | MSigDB lists | TCCAGAT,MIR-516-5P | 104 | 22 | 17758 | 2588 |
NR3C1,RALBP1,ARL4C,PBX3,WHSC1,SRSF5,TRIB2,RASGRP2,GALNT3,GNAS,MID1IP1,RAB11FIP2,SEMA4D,ZNRF2,CSF1,MYLK,PIK3C2B,EFNA5,EGLN3,DLX4,SRSF9,DLAT |
| 4.358e-02 | -3.13 | GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN | 186 | 36 | 17758 | 2588 |
EXPH5,BCAM,UGP2,TUBB4B,SORBS3,ZMYND10,GNB2,LMNA,ITGA2B,HLA-A,ZFP36,ICAM5,ATP8B1,SRP54,VAT1,IL17RA,CD70,CTDSP2,DUSP1,DOCK4,HMMR,CLCN3,COL6A2,RNF19B,CASP4,DPYSL3,PITX2,KDSR,ALDH3B1,CGREF1,NR4A3,RHOBTB2,SSNA1,CBX5,USF2,IFI6 |
| 4.358e-02 | -3.13 | GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_UP | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_UP | 186 | 36 | 17758 | 2588 |
DDX58,MAN2B2,NUDT6,FRMD4A,BACE1,HDAC11,GPR180,TMC1,KREMEN1,WWP2,SLC25A45,SIPA1L2,ZCCHC12,CNTRL,IL6ST,MAP3K9,MTMR10,ETHE1,PLCB2,MPHOSPH9,PHKG2,DUSP1,PTPN18,RAPGEF2,STMN3,LRRC1,ITPR3,DPYSL4,WIPI1,PTK7,HAGHL,MAP3K11,FAM117A,CHPT1,MIIP,SNX30 |
| 4.358e-02 | -3.13 | GSE17721_PAM3CSK4_VS_CPG_16H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_16H_BMDM_UP | 186 | 36 | 17758 | 2588 |
RMND5A,AVPI1,SHPRH,RPS6KA1,COL4A5,XPR1,TMEM63A,PLS3,ADD3,TACC2,IMPAD1,BMP7,SLC44A1,SLC44A2,TSPAN13,LIMCH1,RAB27B,PTPRE,PRODH,ING1,ALDH2,ERLEC1,MOSPD2,ITCH,PCBP3,CALCRL,SLC35C1,EMP3,GGH,B3GALNT2,SFXN1,ARFGAP3,SAMD8,OSR1,RTN3,EHD1 |
| 4.358e-02 | -3.13 | GSE11924_TH1_VS_TH2_CD4_TCELL_DN | MSigDB lists | GSE11924_TH1_VS_TH2_CD4_TCELL_DN | 186 | 36 | 17758 | 2588 |
FAF2,IBTK,FLYWCH2,COL18A1,OAT,LTBP3,TMEM63A,TFAP2E,CA2,FAM189A1,NPNT,RALB,TSPAN6,FAM20B,DLG1,TACSTD2,HSPA13,HEXIM2,TFG,RAB27B,MOXD1,GFI1,SLC12A2,TSPAN33,CYP1B1,GFPT1,LGALS8,NR3C1,TMTC2,MCFD2,ARF4,BCAR3,RND3,NIPSNAP3A,GLB1,USP16 |
| 4.358e-02 | -3.13 | GSE3982_BASOPHIL_VS_TH2_DN | MSigDB lists | GSE3982_BASOPHIL_VS_TH2_DN | 186 | 36 | 17758 | 2588 |
PLA2G4A,SORT1,CKAP2,CALB2,SDC4,TP53,PSMD7,PHLDA1,SYTL2,PER2,MSH2,ADCK2,DIXDC1,TIAM1,MCCC2,DNAI1,CKS2,PPIF,SHARPIN,SPA17,GGH,NUSAP1,SEC14L2,LRRC42,ENDOD1,PLEKHG6,PROM1,FASTKD1,KCNK1,INPP4B,AURKA,TMEM8B,RNASEL,LTBP2,NUP37,ESPL1 |
| 4.358e-02 | -3.13 | GSE17721_POLYIC_VS_CPG_8H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_8H_BMDM_DN | 186 | 36 | 17758 | 2588 |
HSP90B1,SERPINE2,MORF4L2,NCKAP1,OAT,RCN1,ADORA1,ZDHHC12,ARL1,CKS1B,TAGLN2,HLA-C,ZMYM1,MYLIP,CRTAP,CKS2,CERS2,PPIF,ADAM17,TESK1,UBE2A,FAM133B,CD40,MCFD2,LCP1,NMT2,OSBPL2,AP1AR,MAOA,ERAP1,SSNA1,MRPS28,CPEB2,PSMC1,ACOT7,PRKAR1A |
| 4.358e-02 | -3.13 | GSE17721_PAM3CSK4_VS_CPG_12H_BMDM_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_12H_BMDM_UP | 186 | 36 | 17758 | 2588 |
TM2D2,AVPI1,DNAJC3,NDUFA4,TMEM63A,N4BP3,SLC44A1,ECI2,SLAIN2,MANF,RNF26,TRAM1,S100A6,ABCC1,WBP5,LPGAT1,GGH,PRKRA,IDH1,C4orf27,CYB5A,NIN,ZMPSTE24,KLHL2,TIMM8A,PEX2,NAB2,AGBL5,FAM110C,MRPS28,EIF4EBP2,EFNA1,ACADM,RPL22,LTA4H,PRR15 |
| 4.358e-02 | -3.13 | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP | 186 | 36 | 17758 | 2588 |
MRC2,CDK17,ARAP3,AGRN,HOXB7,ETV5,FBXO2,DHX8,PRSS22,TMPRSS4,CYP1A1,KCTD15,SLC16A6,FRAS1,BDH1,MAP3K9,ABCA2,RAB20,EPB41L4B,ACAD8,SGCB,IGSF3,ADAMTS2,HMGN5,PBK,FOXJ2,PLS1,EPHA1,GNA11,PRDM11,KLHL2,CDCA4,MADD,PIEZO1,FZD5,L1CAM |
| 4.358e-02 | -3.13 | GSE3982_BCELL_VS_NKCELL_UP | MSigDB lists | GSE3982_BCELL_VS_NKCELL_UP | 186 | 36 | 17758 | 2588 |
COL9A3,REPS2,CRYM,DNAJC3,ADO,BIK,RASGRP3,BLCAP,CNTNAP2,BAIAP3,DSE,EPS8L2,HDAC9,TNS3,GNB5,KIAA0319,OPN3,BCL6,UBE2J1,GTF2F2,ITM2C,SCN3A,MX1,PRODH,B9D2,ASXL1,C3orf52,EZR,ATP8B3,SAV1,SWAP70,BANK1,FA2H,CCDC6,TTC9,LTA4H |
| 4.358e-02 | -3.13 | GSE3982_BASOPHIL_VS_NKCELL_DN | MSigDB lists | GSE3982_BASOPHIL_VS_NKCELL_DN | 186 | 36 | 17758 | 2588 |
SIGIRR,KIF3C,INPPL1,GGA1,APOO,PLA2G16,EXT2,LTBP3,MYO5C,SGPL1,CTSC,ATRNL1,MCCC2,FARP2,DNAI1,ENPP4,RASGRF1,KCNJ12,CELSR2,TESK1,KLK6,BLVRA,LDB2,PRIM1,OPTN,ENDOD1,GABRD,PLEKHG6,NEIL1,P4HA2,FAM3C,PRPS2,EFNA5,RNASEL,TMEM14A,LTA4H |
| 4.361e-02 | -3.13 | central_nervous_system-brain-glioma-gliomatosis_cerebri | COSMIC cancer mutations | central_nervous_system-brain-glioma-gliomatosis_cerebri | 6 | 3 | 17775 | 2585 |
IDH1,PTEN,TP53 |
| 4.361e-02 | -3.13 | central_nervous_system-frontoparietal-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontoparietal-glioma-oligodendroglioma_Grade_III | 6 | 3 | 17775 | 2585 |
CDKN2C,IDH1,TP53 |
| 4.361e-02 | -3.13 | hyperplastic_polyp | COSMIC cancer mutations | hyperplastic_polyp | 6 | 3 | 17775 | 2585 |
GNAS,CTNNB1,PIK3CA |
| 4.361e-02 | -3.13 | breast-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | breast-carcinoma-clear_cell_carcinoma | 6 | 3 | 17775 | 2585 |
AKT1,EGFR,PIK3CA |
| 4.361e-02 | -3.13 | liver-other-hyperplasia | COSMIC cancer mutations | liver-other-hyperplasia | 6 | 3 | 17775 | 2585 |
GNAS,CTNNB1,IL6ST |
| 4.361e-02 | -3.13 | pituitary-adenoma-ACTH_non_functioning | COSMIC cancer mutations | pituitary-adenoma-ACTH_non_functioning | 6 | 3 | 17775 | 2585 |
CDKN2C,RB1,CDH1 |
| 4.361e-02 | -3.13 | chondroblastic | COSMIC cancer mutations | chondroblastic | 6 | 3 | 17775 | 2585 |
ERBB2,RB1,IDH1 |
| 4.361e-02 | -3.13 | large_intestine-appendix-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-appendix-carcinoma-adenocarcinoma | 6 | 3 | 17775 | 2585 |
GNAS,CTNNB1,TP53 |
| 4.361e-02 | -3.13 | bone-fibula-osteosarcoma | COSMIC cancer mutations | bone-fibula-osteosarcoma | 6 | 3 | 17775 | 2585 |
ERBB2,SS18,EGFR |
| 4.361e-02 | -3.13 | central_nervous_system-frontal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-frontal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | 6 | 3 | 17775 | 2585 |
CTNNB1,IDH1,TP53 |
| 4.361e-02 | -3.13 | large_intestine-serrated_polyp-hyperplastic_polyp | COSMIC cancer mutations | large_intestine-serrated_polyp-hyperplastic_polyp | 6 | 3 | 17775 | 2585 |
GNAS,CTNNB1,PIK3CA |
| 4.361e-02 | -3.13 | central_nervous_system-frontal_lobe-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-oligodendroglioma_Grade_II | 6 | 3 | 17775 | 2585 |
CDKN2C,IDH1,PTEN |
| 4.361e-02 | -3.13 | peritoneum-mesothelioma-biphasic | COSMIC cancer mutations | peritoneum-mesothelioma-biphasic | 6 | 3 | 17775 | 2585 |
PTEN,EGFR,PIK3CA |
| 4.361e-02 | -3.13 | skin-flank-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-flank-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 2585 |
AKT1,PTEN,PIK3CA |
| 4.361e-02 | -3.13 | lung-carcinoma-sarcomatoid_carcinoma | COSMIC cancer mutations | lung-carcinoma-sarcomatoid_carcinoma | 6 | 3 | 17775 | 2585 |
ERBB2,EGFR,PIK3CA |
| 4.361e-02 | -3.13 | central_nervous_system-temporal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-temporal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | 6 | 3 | 17775 | 2585 |
CTNNB1,IDH1,TP53 |
| 4.361e-02 | -3.13 | skin-back-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-back-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 2585 |
AKT1,PTEN,PIK3CA |
| 4.361e-02 | -3.13 | gliomatosis_cerebri | COSMIC cancer mutations | gliomatosis_cerebri | 6 | 3 | 17775 | 2585 |
IDH1,PTEN,TP53 |
| 4.361e-02 | -3.13 | peritoneum-mesothelioma-sarcomatous-fibrous | COSMIC cancer mutations | peritoneum-mesothelioma-sarcomatous-fibrous | 6 | 3 | 17775 | 2585 |
PTEN,EGFR,PIK3CA |
| 4.361e-02 | -3.13 | lymphoepithelioma_like_carcinoma | COSMIC cancer mutations | lymphoepithelioma_like_carcinoma | 6 | 3 | 17775 | 2585 |
KIF5B,EGFR,TP53 |
| 4.361e-02 | -3.13 | skin-abdomen-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-abdomen-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 2585 |
AKT1,PTEN,PIK3CA |
| 4.361e-02 | -3.13 | skin-lower_back-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-lower_back-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 2585 |
AKT1,PTEN,PIK3CA |
| 4.361e-02 | -3.13 | central_nervous_system-temporal_lobe-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-oligodendroglioma_Grade_II | 6 | 3 | 17775 | 2585 |
CDKN2C,IDH1,PTEN |
| 4.361e-02 | -3.13 | peritoneum-mesothelioma-papillary | COSMIC cancer mutations | peritoneum-mesothelioma-papillary | 6 | 3 | 17775 | 2585 |
PTEN,EGFR,PIK3CA |
| 4.361e-02 | -3.13 | gangliocytoma | COSMIC cancer mutations | gangliocytoma | 6 | 3 | 17775 | 2585 |
IDH1,PTEN,GNA11 |
| 4.361e-02 | -3.13 | borderline_tumour | COSMIC cancer mutations | borderline_tumour | 6 | 3 | 17775 | 2585 |
ERBB2,EGFR,PIK3CA |
| 4.361e-02 | -3.13 | central_nervous_system-parietal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-parietal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | 6 | 3 | 17775 | 2585 |
CTNNB1,IDH1,TP53 |
| 4.361e-02 | -3.13 | rhabdoid | COSMIC cancer mutations | rhabdoid | 6 | 3 | 17775 | 2585 |
NF2,AKT1,IDH1 |
| 4.361e-02 | -3.13 | bone-femur-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-femur-chondrosarcoma-dedifferentiated | 6 | 3 | 17775 | 2585 |
RB1,IDH1,TP53 |
| 4.361e-02 | -3.13 | pancreas-other-borderline_tumour | COSMIC cancer mutations | pancreas-other-borderline_tumour | 6 | 3 | 17775 | 2585 |
ERBB2,EGFR,PIK3CA |
| 4.361e-02 | -3.13 | skin-upper_leg-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-upper_leg-other-seborrhoeic_keratosis | 6 | 3 | 17775 | 2585 |
AKT1,PTEN,PIK3CA |
| 4.366e-02 | -3.13 | GSE17721_LPS_VS_CPG_6H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_CPG_6H_BMDM_DN | 192 | 37 | 17758 | 2588 |
SPC25,GNPDA1,INPP5D,RHBDL3,HEXB,ABCG2,KCTD12,RACGAP1,AIP,VPS26A,MESDC2,CCDC92,TFAP4,ZYX,ZCCHC17,DDHD2,DAPK1,SGK1,TUBA4A,SLC37A1,FOPNL,HTATIP2,BLVRA,AKAP3,AKR1E2,FOS,C18orf8,ATP13A2,FAS,DOLPP1,NAB2,CDK18,MAL2,ATP6V1C1,PLIN3,UBE2C,TLL2 |
| 4.366e-02 | -3.13 | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP | 192 | 37 | 17758 | 2588 |
HECA,ARHGEF3,CDK17,CEP70,TRIM24,SHPRH,CENPI,XIAP,ERCC6L,MPP5,CCNL1,ZDHHC21,WDR44,PLK4,HSPA13,RFX5,KCTD3,SEPHS1,HMMR,BAG4,TMEM68,IFITM3,MBNL3,DBR1,SESN1,BORA,CD83,FYN,DNM1L,ANKRD6,ZNF367,CDCA5,INPP4B,ZBTB34,CENPE,HOOK1,ESYT2 |
| 4.366e-02 | -3.13 | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDM_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDM_UP | 192 | 37 | 17758 | 2588 |
CCNI,ANXA3,SPC25,CPT2,GNE,COL4A5,FAM198B,XPR1,SLC25A45,ABCA2,FAM63A,TMEM51,BUB1,ABCD1,PHKA2,EEF1D,PGM1,PTPN18,KIF20A,SLC37A1,CDC20,HTATIP2,KIF1C,PDK3,SKA1,CYP4F3,ANKRD10,SLC25A4,WIPI1,PEX2,PLA2G15,ARRB1,CTSA,PLD1,CD81,MYL12B,CPPED1 |
| 4.366e-02 | -3.13 | GSE17721_PAM3CSK4_VS_CPG_6H_BMDM_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_6H_BMDM_DN | 192 | 37 | 17758 | 2588 |
UNC93B1,KCNAB3,IL15RA,TCTN2,NDRG1,ABCG2,KCTD12,CCDC92,RCN1,FOXP2,APOBEC3B,PDCD10,PIK3AP1,KLF3,SGK3,SORL1,SGK1,FAM102A,IRF2,TESK1,BCL9,NUB1,PARP4,KIAA1109,SAV1,RNF19B,RNPEP,ZFAND5,PRDX4,NUCB1,TWSG1,RAP2C,TRIOBP,HDAC1,NFKBIZ,RELL1,STARD3NL |
| 4.366e-02 | -3.13 | GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDM_DN | 192 | 37 | 17758 | 2588 |
SPRED1,ARHGEF3,CCDC109B,CAMKK1,MTL5,FTH1,MRAS,PRKACA,XPR1,ATP6V0B,SNX18,ARL1,PAPSS1,MDFIC,CTSD,TPCN1,RASGRP1,TMCC2,PTPN18,ELK3,PTPRU,PANK1,PTGER4,PIM3,STK17B,RHOB,GABRD,ETS2,ACYP1,RCBTB2,CSF1,SLC35B3,PIAS2,AURKA,SERPINB6,MAFF,DLAT |
| 4.366e-02 | -3.13 | GSE27786_LIN_NEG_VS_ERYTHROBLAST_DN | MSigDB lists | GSE27786_LIN_NEG_VS_ERYTHROBLAST_DN | 192 | 37 | 17758 | 2588 |
PRKAA2,CPEB4,BLVRB,RHBDL3,NDC80,C5orf30,EGR3,HDAC6,FBLN1,ART5,KCTD9,NOV,CCNA2,ADORA1,KIAA1107,SLC16A6,ELF5,PRC1,KNTC1,C10orf54,WNT3A,PHKG2,USP18,SYNE2,GRIN1,CDK1,EPN3,HS6ST1,PI4K2B,CARHSP1,DUOX1,TRIM69,WIPI1,MFSD2A,TRIOBP,MIIP,E2F8 |
| 4.366e-02 | -3.13 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | 192 | 37 | 17758 | 2588 |
NF2,ST14,TBC1D1,ADO,XYLT1,PPFIBP2,IL27RA,SPR,GSTP1,SLC25A36,TFAP4,INPP5E,CTSC,PAK2,TACSTD2,PLCB2,SPRY2,ATP2B1,LAMP3,MAPKAPK3,FURIN,BLVRA,ICMT,H2AFV,RANBP9,MAPK8IP1,MAP1B,BCAR3,IL1R1,TIMP3,HLF,GDE1,PRCP,PNPLA6,MAOA,PCSK5,ABCG1 |
| 4.366e-02 | -3.13 | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | 192 | 37 | 17758 | 2588 |
KLF2,ST13,ADD1,JKAMP,ATP8A1,DAP,DGKA,XIAP,SELL,ISYNA1,MORF4L2,FAM101B,MAP1LC3B,RABGGTA,SS18,ATP6V0B,RALGPS2,KCNN4,PHTF1,SGK1,FAM102A,PIK3CD,RNASEH2A,LMAN1,GM2A,PPIF,MBP,SEPT6,GLO1,RAD17,SNTB1,FAM109A,SESN1,ANKRD10,TMEM50B,NR4A3,ACADM |
| 4.366e-02 | -3.13 | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDM_UP | 192 | 37 | 17758 | 2588 |
PARP12,LFNG,HLA-E,DNAJC3,FAM134A,DGKA,PDIA3,AES,TEX2,CAMK1D,GALM,RASSF8,PLCG2,RANBP1,TSPAN13,S100A13,TTLL1,HMMR,PGM1,PTPN18,TIMP2,LPGAT1,CBX6,TNS1,MCFD2,IFIT3,TRIM7,NAAA,SYT7,NR1D2,CDCA7L,HDAC1,PDXK,RBM43,PRR15,RAB3IL1,FAM134B |
| 4.369e-02 | -3.13 | V$SRF_C | MSigDB lists | V$SRF_C | 204 | 39 | 17758 | 2588 |
MYL9,LTBP1,SLC2A4,ACVR1,PPP1R12A,SCOC,LMCD1,EGR3,GRK6,DUSP5,PPP2R3A,FOXP2,KCTD15,CYR61,RGS3,CALD1,MITF,FOSB,DUSP10,DIXDC1,SUN2,SSH3,NR4A1,DSTN,LYRM1,FHL2,ERBB2IP,FOS,UNC45B,MYL12A,LCP1,STX10,SLC25A4,ITGA7,MYLK,SPAG7,CTNND1,STARD13,DMPK |
| 4.369e-02 | -3.13 | GSE14769_20MIN_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_20MIN_VS_360MIN_LPS_BMDM_DN | 198 | 38 | 17758 | 2588 |
KIF3C,ZSWIM5,TXN,TMEM184B,ARMC7,DGKA,SUDS3,C5orf30,SELL,CUL1,TXNDC9,CHAC2,BAHD1,ZDHHC21,MAGOHB,TIMP1,XYLT2,CACNA1D,DLG3,SGCB,GFPT1,PHF20L1,ORAI2,TMEM68,ACBD3,BCL9,TRAM2,CASP7,SWAP70,RBL1,HNRNPH2,ITPR1,SIPA1L1,ZDBF2,B4GALT3,TTC39C,JAK3,MAFF |
| 4.370e-02 | -3.13 | HDAC1 (histone deacetylase 1) | protein interactions | 3065 | 466 | 88 | 16036 | 2547 |
ADD1,TSC22D3,SUZ12,CUL4B,SUDS3,TP53,MORF4L2,BAHD1,PRKACA,MAP1LC3B,PHF1,MXD1,TP73,SAP130,CCND1,SS18,PCNA,ZNF687,CTNNB1,CDH1,RABEP2,DACT1,ZFP36,LMO4,BCL6,PPP1CA,ETHE1,MYT1,NR2C1,SMARCA2,ING1,CDYL,CDC20,LOXL2,NFIX,PIAS3,RBL1,STAT1,PRDM5,OVOL1,HDAC1,TLE1,KLF5,KLF11,NR2C2,RUNX2,NKX3-1,ZNF395,UBASH3B,MIER3,ZNF219,PRRG4,MECOM,HDAC9,TFAP4,TOP2A,RB1,TAF1B,BHLHE41,PRKG1,H2AFY,TRIM21,MAPK11,BUB1,GFI1,SYK,SMC4,PHF20L1,DDB2,HES1,TGIF1,NR3C1,HMG20B,WHSC1,RUNX3,ELK1,POLD3,CDK5R1,PITX2,TMEM54,CCDC6,NR1D2,NFKBIA,E2F1,SERPINB5,CABIN1,ACADM,CTBP1 |
| 4.372e-02 | -3.13 | RIPK1 (receptor (TNFRSF)-interacting serine-threonine kinase 1) | protein interactions | 8737 | 75 | 18 | 16036 | 2547 |
MAP3K3,RIPK2,TRAF2,ITCH,RNF11,XIAP,NTAN1,ZFAND5,EGFR,OPTN,FAS,OTUD1,AP1M2,NOD2,DAB2IP,YOD1,MAP3K7,TRAF5 |
| 4.372e-02 | -3.13 | peroxisome | cellular component | GO:0005777 | 132 | 27 | 17570 | 2579 |
ACBD5,SOD1,PEX6,CRYM,AGPS,IDH1,NUDT12,TYSND1,ABCD4,PEX5,IDE,DNM1L,PEX2,ECI2,HMGCL,ABCD1,ACOX2,ACSL4,ACADM,PXMP4,FAR2,FAR1,ISOC1,ALDH3A2,TMEM173,MYO5A,XDH |
| 4.372e-02 | -3.13 | microbody | cellular component | GO:0042579 | 132 | 27 | 17570 | 2579 |
ACBD5,SOD1,PEX6,CRYM,AGPS,IDH1,NUDT12,TYSND1,ABCD4,PEX5,IDE,DNM1L,PEX2,ECI2,HMGCL,ABCD1,ACOX2,ACSL4,ACADM,PXMP4,FAR2,FAR1,ISOC1,ALDH3A2,TMEM173,MYO5A,XDH |
| 4.381e-02 | -3.13 | Signaling mediated by p38-gamma and p38-delta | Pathway Interaction DB | p38gammadeltapathway | 10 | 5 | 2227 | 480 |
SNTA1,CCND1,MAPK13,PKN1,MAPK12 |
| 4.385e-02 | -3.13 | CROSBY_E2F4_TARGETS | MSigDB lists | CROSBY_E2F4_TARGETS | 6 | 3 | 17758 | 2588 |
CENPE,PTTG1,NDC80 |
| 4.385e-02 | -3.13 | chr6p11 | MSigDB lists | chr6p11 | 6 | 3 | 17758 | 2588 |
ENPP4,ENPP5,RAB23 |
| 4.385e-02 | -3.13 | FOURNIER_ACINAR_DEVELOPMENT_EARLY_DN | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_EARLY_DN | 6 | 3 | 17758 | 2588 |
MPRIP,SLC20A1,PHLDA1 |
| 4.385e-02 | -3.13 | YANAGISAWA_LUNG_CANCER_RECURRENCE | MSigDB lists | YANAGISAWA_LUNG_CANCER_RECURRENCE | 6 | 3 | 17758 | 2588 |
ACYP1,RPL39,S100A6 |
| 4.385e-02 | -3.13 | OHASHI_AURKA_TARGETS | MSigDB lists | OHASHI_AURKA_TARGETS | 6 | 3 | 17758 | 2588 |
AURKA,CENPA,DLGAP5 |
| 4.385e-02 | -3.13 | COURTOIS_SENESCENCE_TRIGGERS | MSigDB lists | COURTOIS_SENESCENCE_TRIGGERS | 6 | 3 | 17758 | 2588 |
AKT1,PTEN,E2F1 |
| 4.385e-02 | -3.13 | OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_DN | MSigDB lists | OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_DN | 6 | 3 | 17758 | 2588 |
AKAP17A,TAPBP,PCOLCE |
| 4.385e-02 | -3.13 | WEBER_METHYLATED_HCP_IN_FIBROBLAST_UP | MSigDB lists | WEBER_METHYLATED_HCP_IN_FIBROBLAST_UP | 6 | 3 | 17758 | 2588 |
PHF7,SPA17,PIAS2 |
| 4.385e-02 | -3.13 | SMID_BREAST_CANCER_NORMAL_LIKE_DN | MSigDB lists | SMID_BREAST_CANCER_NORMAL_LIKE_DN | 6 | 3 | 17758 | 2588 |
EPN3,AP1M2,CDS1 |
| 4.385e-02 | -3.13 | OHM_EMBRYONIC_CARCINOMA_UP | MSigDB lists | OHM_EMBRYONIC_CARCINOMA_UP | 6 | 3 | 17758 | 2588 |
CDH1,GSTP1,DAPK1 |
| 4.387e-02 | -3.13 | GuKc | smart domains | SM00072 | 26 | 8 | 9131 | 1455 |
CASK,TJP3,MPP1,DLG1,MPP2,MPP5,DLG3,CACNB4 |
| 4.401e-02 | -3.12 | CSR_EARLY_UP.V1_DN | MSigDB lists | CSR_EARLY_UP.V1_DN | 133 | 27 | 17758 | 2588 |
ERMAP,HSPG2,MOSPD2,PEX6,NBPF3,PDE5A,NPHP3,DHRS3,ADAMTSL4,FAM46C,ELMOD2,SLC9A7,KIAA1147,NMT2,OTUD1,WEE1,GRHL1,ACYP1,TRIM69,TFAP2A,FAM63A,POLL,CDKN1B,ARL4D,AKIP1,ERAP2,SNPH |
| 4.401e-02 | -3.12 | V$AHRARNT_01 | MSigDB lists | V$AHRARNT_01 | 133 | 27 | 17758 | 2588 |
CYP26B1,SOAT1,HES1,ELK3,TM2D2,PAX6,PCDH1,MOSPD2,NR3C1,TACC1,NR4A1,DCHS1,EGR3,PDGFB,PHF1,TFAP4,MAGED2,CNTNAP1,CTGF,BHLHE41,SGK1,CKS1B,AGFG2,USP1,EPB41L4B,ACSL4,RARG |
| 4.401e-02 | -3.12 | ATGTAGC,MIR-221,MIR-222 | MSigDB lists | ATGTAGC,MIR-221,MIR-222 | 133 | 27 | 17758 | 2588 |
SUN2,BMF,RBM24,CDKN1C,EIF5A2,SYBU,MIER3,FNDC3A,VASH1,FOS,ETS1,ARF4,TIMP3,PDCD10,ATP1A1,ETS2,CDK19,RIMS3,AMMECR1,UBE2J1,DCUN1D1,IRF2,CDKN1B,OSBPL7,MYLIP,LIFR,ARNT |
| 4.411e-02 | -3.12 | Ryanodine_recept-rel | interpro domains | IPR015925 | 6 | 3 | 18293 | 2672 |
ITPR2,ITPR3,ITPR1 |
| 4.411e-02 | -3.12 | GED_dom | interpro domains | IPR020850 | 6 | 3 | 18293 | 2672 |
MX1,DNM1L,DNM2 |
| 4.411e-02 | -3.12 | RIH_assoc-dom | interpro domains | IPR013662 | 6 | 3 | 18293 | 2672 |
ITPR2,ITPR3,ITPR1 |
| 4.411e-02 | -3.12 | Dynamin_GTPase_CS | interpro domains | IPR019762 | 6 | 3 | 18293 | 2672 |
MX1,DNM1L,DNM2 |
| 4.411e-02 | -3.12 | GED | interpro domains | IPR003130 | 6 | 3 | 18293 | 2672 |
MX1,DNM1L,DNM2 |
| 4.411e-02 | -3.12 | CTLH/CRA | interpro domains | IPR024964 | 6 | 3 | 18293 | 2672 |
GID8,RMND5A,RANBP9 |
| 4.411e-02 | -3.12 | RIH_dom | interpro domains | IPR000699 | 6 | 3 | 18293 | 2672 |
ITPR2,ITPR3,ITPR1 |
| 4.411e-02 | -3.12 | Dilute_dom | interpro domains | IPR002710 | 6 | 3 | 18293 | 2672 |
MYO5B,MYO5A,MYO5C |
| 4.411e-02 | -3.12 | Anti_prolifrtn | interpro domains | IPR002087 | 6 | 3 | 18293 | 2672 |
BTG3,BTG1,TOB1 |
| 4.411e-02 | -3.12 | Ins145_P3_rcpt | interpro domains | IPR014821 | 6 | 3 | 18293 | 2672 |
ITPR2,ITPR3,ITPR1 |
| 4.411e-02 | -3.12 | CO_DH_flavot_FAD-bd_sub2 | interpro domains | IPR016169 | 6 | 3 | 18293 | 2672 |
AGPS,AOX1,XDH |
| 4.411e-02 | -3.12 | CRA_dom | interpro domains | IPR013144 | 6 | 3 | 18293 | 2672 |
GID8,RMND5A,RANBP9 |
| 4.411e-02 | -3.12 | Ribosomal_S6_kinase_II | interpro domains | IPR016239 | 6 | 3 | 18293 | 2672 |
RPS6KA2,RPS6KA1,RPS6KA3 |
| 4.411e-02 | -3.12 | FAD-bd_2 | interpro domains | IPR016166 | 6 | 3 | 18293 | 2672 |
AGPS,AOX1,XDH |
| 4.411e-02 | -3.12 | Dynamin_central | interpro domains | IPR000375 | 6 | 3 | 18293 | 2672 |
MX1,DNM1L,DNM2 |
| 4.411e-02 | -3.12 | IL-1_rcpt_I/II-typ | interpro domains | IPR004074 | 6 | 3 | 18293 | 2672 |
IL1R1,IL1RAP,IL18R1 |
| 4.411e-02 | -3.12 | Na_trans_cytopl | interpro domains | IPR024583 | 6 | 3 | 18293 | 2672 |
SCN5A,SCN2A,SCN3A |
| 4.425e-02 | -3.12 | GAVIN_FOXP3_TARGETS_CLUSTER_P2 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P2 | 76 | 17 | 17758 | 2588 |
GAA,KIAA1841,SLC2A8,MBNL3,KIF23,PRICKLE1,CASP4,BTG1,AIM1L,SS18,BMP7,CD22,GALNS,ABCB1,SERPINB1,CPE,ARSB |
| 4.428e-02 | -3.12 | Renal function-related traits (eGRFcrea)(PMID:22797727) | GWAS genes | Renal function-related traits (eGRFcrea)(PMID:22797727) | 6 | 3 | 2389 | 350 |
WDR72,RGS14,SHROOM3 |
| 4.428e-02 | -3.12 | Eosinophilic esophagitis (pediatric)(PMID:20208534) | GWAS genes | Eosinophilic esophagitis (pediatric)(PMID:20208534) | 6 | 3 | 2389 | 350 |
SNTB1,SHROOM3,STAT6 |
| 4.428e-02 | -3.12 | Systemic lupus erythematosus(PMID:19838193) | GWAS genes | Systemic lupus erythematosus(PMID:19838193) | 6 | 3 | 2389 | 350 |
RASGRP3,TNIP1,STAT4 |
| 4.435e-02 | -3.12 | MVP (major vault protein) | protein interactions | 9961 | 70 | 17 | 16036 | 2547 |
SLC2A4,PLSCR1,TRAF2,PARP4,TP53,TEP1,AES,RAB3IP,FAM46C,ADAMTSL4,KCTD9,PTEN,VAT1,CHMP4B,KPNA2,CKAP4,MDFI |
| 4.435e-02 | -3.12 | CSK (c-src tyrosine kinase) | protein interactions | 1445 | 70 | 17 | 16036 | 2547 |
PTPN18,AKT1,UBASH3B,FHL2,PLD2,CBL,PRKACA,DAG1,EGFR,RASA1,VCP,ZNF212,INSR,FYN,IGF1R,ARRB1,ERBB3 |
| 4.435e-02 | -3.12 | WAS (Wiskott-Aldrich syndrome) | protein interactions | 7454 | 70 | 17 | 16036 | 2547 |
PACSIN2,TRIP10,ARHGEF7,PIK3R1,TEC,CBL,APPBP2,EGFR,PLCG1,VASP,FYN,DLG1,DNM2,RGS14,WBP4,ARPC2,PACSIN1 |
| 4.436e-02 | -3.12 | AAGTCCA,MIR-422B,MIR-422A | MSigDB lists | AAGTCCA,MIR-422B,MIR-422A | 65 | 15 | 17758 | 2588 |
NEK4,LRRFIP2,UPF3B,ASXL1,STIM1,KIF14,BACE1,C1orf21,SRR,PIK3CA,WHSC1,MORF4L2,GOLT1A,MECOM,UHRF1BP1L |
| 4.436e-02 | -3.12 | LIU_NASOPHARYNGEAL_CARCINOMA | MSigDB lists | LIU_NASOPHARYNGEAL_CARCINOMA | 65 | 15 | 17758 | 2588 |
TAPBP,RAC2,C7orf49,TGFBR3,DDOST,RAP2C,ETNK1,PRKCI,PITPNA,CTTN,ARPC2,B4GALT3,GM2A,HLA-A,EGFR |
| 4.436e-02 | -3.12 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM | 65 | 15 | 17758 | 2588 |
ANXA3,SPP1,PCNA,CDH1,SDC4,CLSTN1,COL18A1,GOT1,SERPINB6,CTSZ,CTSA,GLO1,CTSD,LGALS3BP,VCP |
| 4.459e-02 | -3.11 | BMI1_DN_MEL18_DN.V1_DN | MSigDB lists | BMI1_DN_MEL18_DN.V1_DN | 139 | 28 | 17758 | 2588 |
COL9A3,TRIM2,S100A4,ESRP1,EPHA4,OGDHL,PDE5A,SEPP1,IDH1,FOS,LEPR,KLHL2,IL1R1,DIRAS3,PROM1,SCNN1A,CA2,SLC4A4,METTL7A,GNPTAB,ITGA7,SECTM1,SPINT2,SERPINI1,ACOX2,TSPAN1,IFI6,HOXC13 |
| 4.464e-02 | -3.11 | negative regulation of response to wounding | biological process | GO:1903035 | 153 | 31 | 16441 | 2455 |
CASK,SERPINE2,PSMB4,NLRX1,PLAUR,UBASH3B,PBK,SHARPIN,EPHA4,PTGER4,PPARA,CALCRL,GATA3,F12,PDGFB,ETS1,GSTP1,ABR,SOCS3,IER3,CD109,PDGFA,SPP1,NOV,ADORA1,PRKG1,NOD2,DUSP10,GPER1,MAPK7,NDFIP1 |
| 4.464e-02 | -3.11 | positive regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050731 | 153 | 31 | 16441 | 2455 |
HES1,ADAM17,RIPK2,IL15,TP53,IL18,TEC,YES1,CD40,PDGFB,FLT3,ICAM1,FYN,GPRC5B,ADORA1,SEMA4D,IL6ST,PLPP3,IL31RA,PAK2,NOD2,TNFRSF18,NRG1,EFNA5,LRRK1,ERBB3,EFNA1,WNT3A,CD81,SYK,DVL2 |
| 4.469e-02 | -3.11 | oxoglutarate dehydrogenase complex | cellular component | GO:0045252 | 6 | 3 | 17570 | 2579 |
DHTKD1,MRPS36,OGDHL |
| 4.469e-02 | -3.11 | FACIT collagen trimer | cellular component | GO:0005593 | 6 | 3 | 17570 | 2579 |
COL9A3,COL16A1,COL12A1 |
| 4.469e-02 | -3.11 | platelet dense granule | cellular component | GO:0042827 | 6 | 3 | 17570 | 2579 |
LAMP2,CD63,ITPR1 |
| 4.473e-02 | -3.11 | midbrain | COSMIC cancer mutations | midbrain | 49 | 12 | 17775 | 2585 |
GNAS,CTNNB1,AKT1,FGFR2,RET,SMO,PIK3CA,TP53,IDH1,GNA11,PARM1,EGFR |
| 4.493e-02 | -3.10 | DBNL (drebrin-like) | protein interactions | 28988 | 50 | 13 | 16036 | 2547 |
CASP3,CMAS,RBM23,DNPEP,PPME1,ERO1A,FGD6,ECI2,CUL1,PLIN3,CBL,SYK,SH2D4A |
| 4.503e-02 | -3.10 | human chr3q24 | chromosome location | human chr3q24 | 19 | 5 | 26250 | 2805 |
HPS3,PLSCR4,PLOD2,C3orf58,CHST2 |
| 4.504e-02 | -3.10 | V$NFE2_01 | MSigDB lists | V$NFE2_01 | 259 | 48 | 17758 | 2588 |
DOC2A,GAA,SPRED1,CMAS,LRRFIP2,CAPN12,GCAT,CALB2,FBXO2,PSMD7,GSTP1,S100A2,PRR7,PAK6,VASP,IRAK1,SHC3,NECAB3,SLC16A6,MITF,ABCA2,VAT1,ABCD1,TINAGL1,SNX10,TBC1D10B,TUBA4A,MDFI,ATL1,LONRF3,CAPN6,KBTBD8,TMEM151A,ZFAND5,NDRG3,GABARAPL1,TBC1D17,H1F0,MAP2,SERPINB5,FBXO44,RCAN2,HS3ST3B1,DRP2,MAFF,COBL,TOB1,MAPK12 |
| 4.505e-02 | -3.10 | transcription factor activity, protein binding | molecular function | GO:0000988 | 585 | 102 | 16491 | 2452 |
ELK4,TRIM24,CRYM,LMCD1,GATA3,TAF6L,LPIN3,MXD1,PER2,CCND1,SAP130,HELZ2,SS18,HSF2,SP100,CTNNB1,ZCCHC12,IL31RA,CRY2,NFKB2,MED30,THRB,SIRT1,SMARCA2,KCNIP3,CITED4,ASXL1,DRAP1,UXT,CDYL,NFE2L1,HTATIP2,LOXL2,LDB2,GTF2A2,SP4,ARHGAP35,AHRR,HSF4,JADE1,KLF12,WWTR1,TLE1,HDAC1,NRG1,NFKBIZ,E2F8,ARNT,CBX4,NR2C2,AES,NOTCH2,PKN1,AIP,PSIP1,HDAC9,WWP2,ELF3,ZNF212,GBX2,TFAP4,ZFX,E2F7,RB1,TAF1B,BHLHE41,GTF2F2,TFAP2A,BRD7,CITED2,WNT3A,NCOA2,MED22,NFE2L3,TGIF1,ELK3,DCAF6,NR3C1,PPARA,FHL2,MAML2,NFIB,BCL10,CNOT2,PITX2,BTG1,NCOA3,SERTAD2,ATXN7L3,SETD3,TBX18,RAP2C,NMI,NAB2,TADA2B,PIAS2,SFMBT1,HMGA1,TOB1,CTBP1,USP16,KLF7 |
| 4.505e-02 | -3.10 | hippocampus development | biological process | GO:0021766 | 69 | 16 | 16441 | 2455 |
ANXA3,CASP3,NF2,BBS2,CDK5R1,MDK,TP73,TSC1,PTEN,PHLPP2,KIF14,SMO,NR4A3,WNT3A,ZBTB18,DRD1 |
| 4.505e-02 | -3.10 | negative regulation of MAP kinase activity | biological process | GO:0043407 | 69 | 16 | 16441 | 2455 |
SPRED1,DUSP4,GSTP1,DUSP5,TP73,PTPRJ,STK38,RGS3,BMP7,SORL1,DUSP10,DAB2IP,RGS14,SPRY2,HIPK3,DUSP1 |
| 4.506e-02 | -3.10 | NUCLEAR_ENVELOPE_ENDOPLASMIC_RETICULUM_NETWORK | MSigDB lists | NUCLEAR_ENVELOPE_ENDOPLASMIC_RETICULUM_NETWORK | 93 | 20 | 17758 | 2588 |
PIGC,HSP90B1,AMFR,ERP44,KTN1,EXT2,TAPBP,CASP7,DDOST,STIM1,NECAB3,SLC9A6,LMAN2L,DOLPP1,BAX,RPN2,STT3B,POMT1,LMAN1,TMX1 |
| 4.508e-02 | -3.10 | BROWNE_HCMV_INFECTION_24HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_DN | 145 | 29 | 17758 | 2588 |
PRSS23,SSH1,LGALS3,GRIK2,S100A4,BNIP3L,DIAPH2,MEST,ECI1,TP53I3,NOV,BTG1,DDAH1,TIMP3,RPS6KA2,TAF1B,PTEN,COL13A1,ATP5H,CALD1,HOXA9,N4BP3,PRKG1,ACTA2,ERCC2,MTMR11,SGCB,ARHGEF9,ABCC1 |
| 4.513e-02 | -3.10 | HIPK2 (homeodomain interacting protein kinase 2) | protein interactions | 28996 | 60 | 15 | 16036 | 2547 |
TP73,MBP,NKX3-1,PAX6,SP100,DCAF7,TP53,MYBL2,CUL1,CHMP4B,HMGA1,MAP3K7,MYBL1,RANBP9,CBX4 |
| 4.513e-02 | -3.10 | PSMD10 (proteasome 26S subunit, non-ATPase 10) | protein interactions | 5716 | 60 | 15 | 16036 | 2547 |
CCDC92,RB1,DDAH1,PSMD1,RHOA,PSMD3,PSMC2,RNF11,TP53,PSMD7,CCDC74B,PSMC1,LMNA,EEF1D,WWP2 |
| 4.514e-02 | -3.10 | MAP kinase activity | molecular function | GO:0004707 | 14 | 5 | 16491 | 2452 |
MAPK11,MAPK13,MAPK4,MAPK7,MAPK12 |
| 4.518e-02 | -3.10 | pancreas-carcinoid-endocrine_tumour-gastrinoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-gastrinoma | 10 | 4 | 17775 | 2585 |
GNAS,CDKN2C,CTNNB1,PTEN |
| 4.518e-02 | -3.10 | ovary-adenoma-Brenner_tumour | COSMIC cancer mutations | ovary-adenoma-Brenner_tumour | 10 | 4 | 17775 | 2585 |
ERBB2,CTNNB1,PIK3CA,TP53 |
| 4.518e-02 | -3.10 | metaplasia | COSMIC cancer mutations | metaplasia | 10 | 4 | 17775 | 2585 |
CTNNB1,PTEN,EGFR,TP53 |
| 4.518e-02 | -3.10 | large_intestine-colon-carcinoid-endocrine_tumour | COSMIC cancer mutations | large_intestine-colon-carcinoid-endocrine_tumour | 10 | 4 | 17775 | 2585 |
CTNNB1,AKT1,EGFR,TP53 |
| 4.518e-02 | -3.10 | epithelioid_sarcoma | COSMIC cancer mutations | epithelioid_sarcoma | 10 | 4 | 17775 | 2585 |
SS18,CTNNB1,IDH1,EGFR |
| 4.518e-02 | -3.10 | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-non_functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-non_functioning | 10 | 4 | 17775 | 2585 |
GNAS,ATP1A1,CACNA1D,CTNNB1 |
| 4.518e-02 | -3.10 | soft_tissue-fibrous_tissue_and_uncertain_origin-epithelioid_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-epithelioid_sarcoma | 10 | 4 | 17775 | 2585 |
SS18,CTNNB1,IDH1,EGFR |
| 4.518e-02 | -3.10 | osteoblastic | COSMIC cancer mutations | osteoblastic | 10 | 4 | 17775 | 2585 |
ERBB2,RB1,IDH1,EGFR |
| 4.518e-02 | -3.10 | genital_tract-extragonadal-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-non_seminoma | 10 | 4 | 17775 | 2585 |
CBL,CTNNB1,PTEN,TP53 |
| 4.518e-02 | -3.10 | small_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-carcinoma-adenocarcinoma | 10 | 4 | 17775 | 2585 |
CTNNB1,IDH1,EGFR,TP53 |
| 4.519e-02 | -3.10 | STAM2 (signal transducing adaptor molecule (SH3 domain and ITAM motif) 2) | protein interactions | 10254 | 55 | 14 | 16036 | 2547 |
FAM189A2,JAK1,TIMM8A,ITCH,RNF11,UBE2D2,TP53,LITAF,JAK3,CBX5,ZFYVE9,SH2D4A,VCP,EGFR |
| 4.519e-02 | -3.10 | VARS (valyl-tRNA synthetase) | protein interactions | 7407 | 55 | 14 | 16036 | 2547 |
OTUD5,HLA-B,PAFAH1B3,LAP3,EFHD2,MAPK11,TMOD2,KNTC1,FBXO6,DMWD,MCFD2,FOS,EEF1D,EGFR |
| 4.519e-02 | -3.10 | TAX1BP1 (Tax1 (human T-cell leukemia virus type I) binding protein 1) | protein interactions | 8887 | 55 | 14 | 16036 | 2547 |
KIF5B,NMRK1,TBC1D17,FAM189A2,TNIP1,LGALS8,DSTN,ITCH,RNF11,REEP4,MAP1LC3B,STARD13,VCP,OPTN |
| 4.519e-02 | -3.10 | regulation of fat cell differentiation | biological process | GO:0045598 | 102 | 22 | 16441 | 2455 |
SIRT1,HES1,SORT1,WNT10B,AKT1,ASXL1,GATA3,TRIB2,HDAC6,SAV1,MECOM,BMP2,PTGS2,ENPP1,GATA2,DACT1,WWTR1,E2F1,DUSP10,KLF5,GPER1,WNT3A |
| 4.521e-02 | -3.10 | human chr9q31.2 | chromosome location | human chr9q31.2 | 8 | 3 | 26250 | 2805 |
ZNF462,CTNNAL1,SLC44A1 |
| 4.521e-02 | -3.10 | human chr20q13.1 | chromosome location | human chr20q13.1 | 8 | 3 | 26250 | 2805 |
CTSA,CDH22,MYBL2 |
| 4.521e-02 | -3.10 | human chr10q25 | chromosome location | human chr10q25 | 8 | 3 | 26250 | 2805 |
CASP7,DUSP5,FAM45A |
| 4.521e-02 | -3.10 | human chr9q21.12 | chromosome location | human chr9q21.12 | 8 | 3 | 26250 | 2805 |
APBA1,TMC1,MAMDC2 |
| 4.521e-02 | -3.10 | positive regulation of blood vessel endothelial cell migration | biological process | GO:0043536 | 23 | 7 | 16441 | 2455 |
PTGS2,PLCG1,AKT1,PDGFB,HSPB1,SRPX2,HDAC9 |
| 4.521e-02 | -3.10 | positive regulation of mesonephros development | biological process | GO:0061213 | 23 | 7 | 16441 | 2455 |
GATA3,SOX8,HOXB7,LGR4,SOX9,SIX4,SMO |
| 4.521e-02 | -3.10 | multicellular organismal reproductive behavior | biological process | GO:0033057 | 23 | 7 | 16441 | 2455 |
THRB,GRN,PTEN,THRA,HEXB,GRIN1,DRD1 |
| 4.521e-02 | -3.10 | cellular response to epidermal growth factor stimulus | biological process | GO:0071364 | 23 | 7 | 16441 | 2455 |
DAB2IP,PLCG1,BAG4,AKT1,IQGAP1,EGFR,SOX9 |
| 4.521e-02 | -3.10 | regulation of transcription initiation from RNA polymerase II promoter | biological process | GO:0060260 | 23 | 7 | 16441 | 2455 |
CTNNBIP1,WNT10B,THRA,PSMC1,AHR,PSMC2,GTF2F2 |
| 4.521e-02 | -3.10 | leukocyte apoptotic process | biological process | GO:0071887 | 23 | 7 | 16441 | 2455 |
CTSL,PKN1,AKT1,SIVA1,FAS,BCL10,BAX |
| 4.530e-02 | -3.09 | V$CP2_01 | MSigDB lists | V$CP2_01 | 253 | 47 | 17758 | 2588 |
SORT1,BMF,PAX6,GRHL2,PPP1R12A,IGFBP6,SLC41A1,ETV5,ATP6V1E2,GATA3,CALM3,DHRS3,DDR1,LTBP3,SLC25A35,HDAC9,CALM2,AIM1L,KCTD15,PHF7,RGS3,CALD1,CABP1,GPC3,PAK2,DAB2IP,USP1,PSMA5,IGDCC4,MDFI,ACBD5,TGIF1,SMARCA2,RHOA,TMEM43,PHLDB3,CALM1,DCHS1,KIF1C,VCP,RASGRP2,GNAS,NFKBIZ,C1orf43,ARF6,RGMA,DOCK9 |
| 4.530e-02 | -3.09 | CREB1 (cAMP responsive element binding protein 1) | protein interactions | 1385 | 112 | 25 | 16036 | 2547 |
SIRT1,KCNIP3,AKT1,NR3C1,THRA,RPS6KA1,SUZ12,SOX9,TP53,FHL2,PRKACA,MAPKAPK2,CCND1,RPS6KA2,CTNNB1,HTT,CCDC6,GTF2F2,PRKG1,SGK1,HDAC1,NR4A2,PPP1CA,HIPK3,RPS6KA3 |
| 4.533e-02 | -3.09 | MODULE_84 | MSigDB lists | MODULE_84 | 527 | 91 | 17758 | 2588 |
MYL9,HSPG2,S100A11,THRA,TSC22D3,TAP1,DGKA,NRG2,IL27RA,BAIAP3,SDC1,SPSB1,IER3,CCND1,ZYX,TYMP,SRPX,CDH1,TACC2,LMO4,CAPG,DNM2,BCL6,IFIT1,LGMN,PTPRE,IL1RAP,LAMP3,CYP1B1,MX1,COL6A2,TIMP2,LAP3,S100A4,PLEKHO1,ARHGDIB,ITPR3,CCNF,STK17B,LCP1,MDK,ENPP1,TBX1,SECTM1,STAT1,BMP1,NRGN,ABCA1,GRN,PARP12,PCOLCE,LGALS3,PARP14,ITGA6,SELL,TRIB2,SEPP1,DHRS3,ADAMTSL4,TSPAN7,ICAM1,HLA-A,M6PR,SPP1,RAC2,CXCL16,CTSC,CD22,COL6A1,ACTA2,IGFBP2,CADPS2,HLA-C,C10orf54,WNT10B,PLSCR1,STAT4,EMP3,TCF7,RUNX3,IL1R1,CD8A,SERPINA1,PVRL2,SEMA4D,DHRS2,ITPR1,RAB31,RAB3IL1,DEF6,IRF1 |
| 4.536e-02 | -3.09 | PID_FOXO_PATHWAY | MSigDB lists | PID_FOXO_PATHWAY | 49 | 12 | 17758 | 2588 |
SIRT1,PLK1,AKT1,CTNNB1,RALB,CSNK1G1,SOD2,BCL6,CDKN1B,SGK1,CCNB1,ZFAND5 |
| 4.536e-02 | -3.09 | HOFMANN_CELL_LYMPHOMA_UP | MSigDB lists | HOFMANN_CELL_LYMPHOMA_UP | 49 | 12 | 17758 | 2588 |
IL1R1,CCND1,RB1,TAF5,H1F0,TFAP2A,MYBL2,CKS1B,IL18,IL13RA1,YES1,LIFR |
| 4.536e-02 | -3.09 | ATCMNTCCGY_UNKNOWN | MSigDB lists | ATCMNTCCGY_UNKNOWN | 49 | 12 | 17758 | 2588 |
TSC1,CAMK2N2,PAX6,RBL1,HOXA9,UBE2D2,COL4A5,HEXIM2,KDM3A,GNB2,STK35,CCDC88A |
| 4.536e-02 | -3.09 | YANG_BREAST_CANCER_ESR1_LASER_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_LASER_DN | 49 | 12 | 17758 | 2588 |
SGCE,UGT8,KIF14,MCCC1,ARL4C,UBE2J1,PPP1CB,PLD1,GSTP1,CYP39A1,PLS3,ARHGEF4 |
| 4.544e-02 | -3.09 | IL-3 Signaling Pathway | WikiPathways | WP286 | 104 | 24 | 4455 | 729 |
KCNIP3,AKT1,INPP5D,PIK3R1,MRAS,BCL2L1,TEC,CBL,PRKACA,SOCS3,MAPKAPK2,RAC2,FYN,JAK1,GATA2,STAT6,BAX,STAT1,PIK3CA,PIK3CD,MAPK7,HSPB1,SYK,GAB1 |
| 4.549e-02 | -3.09 | REACTOME_PECAM1_INTERACTIONS | MSigDB lists | REACTOME_PECAM1_INTERACTIONS | 10 | 4 | 17758 | 2588 |
PLCG1,FYN,YES1,ITGAV |
| 4.549e-02 | -3.09 | HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP | MSigDB lists | HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP | 10 | 4 | 17758 | 2588 |
KLF11,PLCG1,CELSR2,ELK1 |
| 4.549e-02 | -3.09 | OXFORD_RALA_AND_RALB_TARGETS_UP | MSigDB lists | OXFORD_RALA_AND_RALB_TARGETS_UP | 10 | 4 | 17758 | 2588 |
CCNE2,WNT10B,SMYD5,ETV4 |
| 4.549e-02 | -3.09 | PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT | MSigDB lists | PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT | 10 | 4 | 17758 | 2588 |
SERPINI1,SOD1,UGT8,ALDH3A2 |
| 4.549e-02 | -3.09 | TSUDA_ALVEOLAR_SOFT_PART_SARCOMA | MSigDB lists | TSUDA_ALVEOLAR_SOFT_PART_SARCOMA | 10 | 4 | 17758 | 2588 |
MAPKAPK2,PRKAG2,PACSIN2,PIM1 |
| 4.549e-02 | -3.09 | SHIRAISHI_PLZF_TARGETS_UP | MSigDB lists | SHIRAISHI_PLZF_TARGETS_UP | 10 | 4 | 17758 | 2588 |
OSMR,KLF9,OAS3,PRICKLE3 |
| 4.549e-02 | -3.09 | ANTIPORTER_ACTIVITY | MSigDB lists | ANTIPORTER_ACTIVITY | 10 | 4 | 17758 | 2588 |
SLC9A6,SLC9A2,SLC9A7,SLC4A3 |
| 4.549e-02 | -3.09 | EPITHELIAL_TO_MESENCHYMAL_TRANSITION | MSigDB lists | EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 10 | 4 | 17758 | 2588 |
BMP2,CTNNB1,S100A4,BMP7 |
| 4.549e-02 | -3.09 | KEGG_LIMONENE_AND_PINENE_DEGRADATION | MSigDB lists | KEGG_LIMONENE_AND_PINENE_DEGRADATION | 10 | 4 | 17758 | 2588 |
YOD1,ALDH7A1,ALDH2,ALDH3A2 |
| 4.549e-02 | -3.09 | REGULATION_OF_CELL_CELL_ADHESION | MSigDB lists | REGULATION_OF_CELL_CELL_ADHESION | 10 | 4 | 17758 | 2588 |
NF2,PTEN,ACVRL1,RASA1 |
| 4.549e-02 | -3.09 | MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | MITOTIC_SPINDLE_ORGANIZATION_AND_BIOGENESIS | 10 | 4 | 17758 | 2588 |
KIF23,SUN2,KIF11,PRC1 |
| 4.549e-02 | -3.09 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | MSigDB lists | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | 10 | 4 | 17758 | 2588 |
TUBG1,CCNB1,CDK1,TUBGCP6 |
| 4.549e-02 | -3.09 | POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | MSigDB lists | POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS | 10 | 4 | 17758 | 2588 |
ARHGEF10L,SORBS3,NF2,ARF6 |
| 4.549e-02 | -3.09 | CHASSOT_SKIN_WOUND | MSigDB lists | CHASSOT_SKIN_WOUND | 10 | 4 | 17758 | 2588 |
KLF2,EGR3,FOS,FOSB |
| 4.549e-02 | -3.09 | ATGAAGG,MIR-205 | MSigDB lists | ATGAAGG,MIR-205 | 151 | 30 | 17758 | 2588 |
INPPL1,SORBS1,RUNX2,MMD,NDUFA4,TRIM35,YES1,SRSF5,SEPT4,PJA2,LHFPL2,NFAT5,SP4,MID1IP1,KLF12,RBM47,KHNYN,CDK19,LIMK1,VASN,DOK4,E2F1,ERBB3,FAM84B,BTBD3,RTN3,CPEB2,RPS6KA3,ACOT7,TRAK2 |
| 4.550e-02 | -3.09 | IL-7 Signaling Pathway | WikiPathways | WP205 | 44 | 12 | 4455 | 729 |
IRS2,RB1,FYN,CCNA2,JAK1,AKT1,PIK3R1,BAX,STAT1,CBL,JAK3,IRF1 |
| 4.554e-02 | -3.09 | V$STAT6_02 | MSigDB lists | V$STAT6_02 | 247 | 46 | 17758 | 2588 |
ARAP3,CPEB4,RHBDL3,CD274,CAMK1D,DOCK11,GNB2,NFAT5,ZNF385B,SAP130,CD109,BMP2,VASP,PDCD10,ACAP2,CTNNB1,RNF128,ZNRF2,CDKL5,RGS3,SGK1,TWIST1,PDE4D,SCN2A,ZRANB1,CITED2,PLCB2,SNX8,DOCK4,MAP3K3,CITED4,VAMP3,SLC35C1,RUNX3,ITPR3,GLT8D2,RANBP9,ATP13A2,CRTC2,CAMK2N2,PLEKHH2,TBC1D17,PGM2L1,EGFL7,SERPINI1,HMGA1 |
| 4.572e-02 | -3.09 | mesoderm development | biological process | GO:0007498 | 119 | 25 | 16441 | 2455 |
EPB41L5,ACVR1,NF2,NCKAP1,MEST,PRKACA,EXT2,MESDC2,IRX3,ITGA3,ETS2,HTT,TWSG1,FGFR2,TBX1,BMP7,SECTM1,SMO,NR4A3,OVOL1,GDF11,OSR1,WNT3A,CITED2,PRKAR1A |
| 4.576e-02 | -3.08 | V$ETS1_B | MSigDB lists | V$ETS1_B | 241 | 45 | 17758 | 2588 |
SPRED1,PAX6,GPR107,PSME2,CAST,TSC22D3,RASA2,ITPR2,CAMK1D,APBA1,PDGFB,CMTM6,ZNF687,SHC3,RGS3,ADAM15,TWIST1,DAB2IP,CACNA1D,SCN2A,PLCB2,RBMS2,MCTP1,ELK3,SH3BGRL,FURIN,KIF1C,ITPR3,SPNS3,LCP1,EPN3,NT5C2,FYN,PLEKHH2,KLF12,MADD,RAP2C,APPL2,NRG1,HMGA1,RGS14,STARD13,DEF6,RGMA,ABCG1 |
| 4.582e-02 | -3.08 | MIR_motif | interpro domains | IPR016093 | 10 | 4 | 18293 | 2672 |
ITPR2,ITPR3,POMT1,ITPR1 |
| 4.582e-02 | -3.08 | IL-1_rcpt_fam | interpro domains | IPR015621 | 10 | 4 | 18293 | 2672 |
IL1R1,SIGIRR,IL1RAP,IL18R1 |
| 4.582e-02 | -3.08 | Anoctamin | interpro domains | IPR007632 | 10 | 4 | 18293 | 2672 |
ANO9,ANO4,ANO1,ANO6 |
| 4.582e-02 | -3.08 | Biotin_lipoyl | interpro domains | IPR000089 | 10 | 4 | 18293 | 2672 |
ACACB,PDHX,MCCC1,DLAT |
| 4.582e-02 | -3.08 | IPPc | interpro domains | IPR000300 | 10 | 4 | 18293 | 2672 |
INPP5E,INPPL1,OCRL,INPP5D |
| 4.582e-02 | -3.08 | MKP | interpro domains | IPR008343 | 10 | 4 | 18293 | 2672 |
DUSP10,DUSP4,DUSP5,DUSP1 |
| 4.583e-02 | -3.08 | GSE6269_FLU_VS_STREP_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_STREP_AUREUS_INF_PBMC_UP | 157 | 31 | 17758 | 2588 |
MX1,KLF2,RECQL,PNISR,PARP12,IFITM3,TRIM5,ACTR8,HERC5,HERC6,ETS1,PGAP1,PDHX,LGALS3BP,RHOB,PRIM1,PLS3,HLA-B,NCOA3,ADD3,KLF12,TRANK1,TAF1B,C19orf66,STAT1,IRF7,USP1,OAS3,IFI6,DLAT,LAMP3 |
| 4.587e-02 | -3.08 | PSMD2 (proteasome 26S subunit, non-ATPase 2) | protein interactions | 5708 | 139 | 30 | 16036 | 2547 |
GFPT1,UFD1L,FAF2,PINK1,PSMB4,PSME2,NDRG1,JKAMP,CALM1,RNF11,NUB1,PSMD7,PSMD10,PSMA4,HLA-A,EGFR,RAD23A,CCDC92,PSMD1,PFKL,PSMD3,ITPR1,PSMC2,CCDC74B,CPLX1,LRIF1,PSMC1,PSMA5,ABCC1,RAD21 |
| 4.587e-02 | -3.08 | regulation of response to wounding | biological process | GO:1903034 | 386 | 70 | 16441 | 2455 |
NLRX1,IL15,EPHA4,ARFGEF1,XIAP,GATA3,IL18,SLC7A2,PDGFB,IER3,PDGFA,CD46,ZYX,NOV,FAM46A,IL6ST,BCL6,DUSP10,F2R,ENPP4,CD55,TNIP1,DMTN,PBK,PTGER4,PRKCQ,F12,CASP4,ABR,SOCS3,PTGS2,GPRC5B,HPSE,CDK19,MYLK,NOD2,MAPK13,F2RL1,TC2N,SERPINE2,UBASH3B,TEC,GSTP1,ETS1,CD109,SPP1,ADORA1,PTEN,PIK3AP1,PRKG1,IL17RA,TNFRSF12A,MAPK7,SYK,CASK,PSMB4,PLAUR,SHARPIN,ANO6,VAMP3,PPARA,CALCRL,PTPRF,IL1R1,NR1D2,PLPP3,OSMR,STK39,GPER1,NDFIP1 |
| 4.588e-02 | -3.08 | galactose metabolic process | biological process | GO:0006012 | 14 | 5 | 16441 | 2455 |
PGM2L1,GLB1,GALK1,PGM1,GALM |
| 4.588e-02 | -3.08 | regulation of spindle checkpoint | biological process | GO:0090231 | 14 | 5 | 16441 | 2455 |
XRCC3,CCNB1,GEN1,NDRG1,DUSP1 |
| 4.588e-02 | -3.08 | phosphatidylglycerol biosynthetic process | biological process | GO:0006655 | 14 | 5 | 16441 | 2455 |
SLC27A1,PLD2,CDS2,PLD1,CDS1 |
| 4.588e-02 | -3.08 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:2001241 | 14 | 5 | 16441 | 2455 |
PPP1CA,SRPX,RET,FAS,BAX |
| 4.588e-02 | -3.08 | long term synaptic depression | biological process | GO:0060292 | 14 | 5 | 16441 | 2455 |
GRID2IP,PTEN,PLK2,PICK1,DRD1 |
| 4.588e-02 | -3.08 | regulation of sister chromatid cohesion | biological process | GO:0007063 | 14 | 5 | 16441 | 2455 |
BUB1,RB1,CTNNB1,ESPL1,CDCA5 |
| 4.588e-02 | -3.08 | atrial septum morphogenesis | biological process | GO:0060413 | 14 | 5 | 16441 | 2455 |
WHSC1,NOTCH2,ACVR1,CYR61,SMO |
| 4.588e-02 | -3.08 | positive regulation of fatty acid oxidation | biological process | GO:0046321 | 14 | 5 | 16441 | 2455 |
IRS2,TWIST1,PLIN5,PPARA,NR4A3 |
| 4.588e-02 | -3.08 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological process | GO:0006978 | 14 | 5 | 16441 | 2455 |
TP73,TFAP4,SP100,FOXM1,TP53 |
| 4.588e-02 | -3.08 | positive regulation of coenzyme metabolic process | biological process | GO:0051197 | 14 | 5 | 16441 | 2455 |
PRKAA2,P2RX7,INSR,ARNT,PRKAA1 |
| 4.588e-02 | -3.08 | cerebellar granular layer development | biological process | GO:0021681 | 14 | 5 | 16441 | 2455 |
MDK,SERPINE2,KNDC1,KIF14,NFIX |
| 4.588e-02 | -3.08 | metanephric mesenchyme development | biological process | GO:0072075 | 14 | 5 | 16441 | 2455 |
PKD2,OSR1,BMP7,SIX4,STAT1 |
| 4.588e-02 | -3.08 | detection of calcium ion | biological process | GO:0005513 | 14 | 5 | 16441 | 2455 |
CALM3,CALM2,KCNMB4,STIM1,CALM1 |
| 4.588e-02 | -3.08 | negative regulation of dendrite morphogenesis | biological process | GO:0050774 | 14 | 5 | 16441 | 2455 |
EFNA1,PTEN,CIT,RAPGEF2,NGEF |
| 4.588e-02 | -3.08 | regulation of energy homeostasis | biological process | GO:2000505 | 14 | 5 | 16441 | 2455 |
PRKAA2,NR1D2,PRKAA1,PASK,NR4A3 |
| 4.588e-02 | -3.08 | contractile actin filament bundle assembly | biological process | GO:0030038 | 14 | 5 | 16441 | 2455 |
ARRB1,ZYX,PDCD10,SORBS1,RHOA |
| 4.588e-02 | -3.08 | regulation of non-canonical Wnt signaling pathway | biological process | GO:2000050 | 14 | 5 | 16441 | 2455 |
ZNRF3,NPHP3,ANKRD6,DACT1,NKD1 |
| 4.588e-02 | -3.08 | stress fiber assembly | biological process | GO:0043149 | 14 | 5 | 16441 | 2455 |
ARRB1,ZYX,PDCD10,SORBS1,RHOA |
| 4.588e-02 | -3.08 | positive regulation of cofactor metabolic process | biological process | GO:0051194 | 14 | 5 | 16441 | 2455 |
PRKAA2,P2RX7,INSR,ARNT,PRKAA1 |
| 4.590e-02 | -3.08 | SLC9A3R1 (solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1) | protein interactions | 9368 | 91 | 21 | 16036 | 2547 |
CLCN3,NF2,TACC1,EZR,PDIA3,YES1,NANS,GRK6,GNA11,EGFR,BCL10,CTNNB1,PTEN,PHLPP2,PPME1,PCYOX1,PIK3CA,MDH1,PLCB2,RPS6KA3,CAPN1 |
| 4.596e-02 | -3.08 | V$NRF1_Q6 | MSigDB lists | V$NRF1_Q6 | 235 | 44 | 17758 | 2588 |
CCNI,PPP4R4,PPP1R12A,DNAJC3,ADO,MPP5,CNTROB,PDXDC1,AIP,PHF1,IRF2BPL,PPP1R10,CDK16,PPME1,KCNK5,FAM13B,FUT8,SRR,TMEM143,TUBG1,VAT1,TECR,BTBD3,FGFR1OP2,FAM134C,SMC4,CKS2,HMMR,RHOA,CBX6,C12orf65,FXR2,SNX12,PSMA4,CNTNAP1,MAGED2,SPINT2,ARFGAP3,SPRY4,PLOD3,USF2,NRGN,CCDC97,SRSF9 |
| 4.612e-02 | -3.08 | mitotic cell cycle checkpoint | biological process | GO:0007093 | 165 | 33 | 16441 | 2455 |
PSME2,TP53,PSMD7,PSMD10,PSME1,BCL2L1,FANCI,IER3,TP73,CCND1,TOP2A,RB1,CCNA2,PSMD1,PSMC2,DLG1,MSH2,CDKN1B,BUB1,KNTC1,PSMA5,PLK1,ZWINT,PSMB4,CDC20,RAD17,CDK1,PSMA4,PSMD3,PLK2,MAD2L1BP,UBE2C,PSMC1 |
| 4.614e-02 | -3.08 | response to amine | biological process | GO:0014075 | 48 | 12 | 16441 | 2455 |
CALM2,SOD1,DPYSL2,CTSB,CALM1,GNAL,GRIN1,CALM3,NR4A2,ICAM1,HDAC9,DRD1 |
| 4.614e-02 | -3.08 | regulation of lipid catabolic process | biological process | GO:0050994 | 48 | 12 | 16441 | 2455 |
IRS2,ADORA1,AKT1,THRA,PNPLA2,PRKAA1,PPARA,TWIST1,IDH1,TYSND1,PLIN5,GPLD1 |
| 4.614e-02 | -3.08 | regulation of immunoglobulin production | biological process | GO:0002637 | 48 | 12 | 16441 | 2455 |
HLA-E,STAT6,TRAF2,BCL6,VAMP3,WHSC1,TMBIM6,IL27RA,PKN1,CD40,NDFIP1,MSH6 |
| 4.614e-02 | -3.08 | clathrin-coated vesicle | cellular component | GO:0030136 | 156 | 31 | 17570 | 2579 |
VPS11,SORT1,SLC2A4,GPR107,FZD4,DENND1B,FURIN,VAMP3,TGOLN2,FAM109A,SNX9,BCAP31,EGFR,EPN3,LDLRAP1,AP1M2,SNX18,HTT,WIPI1,OCRL,FCHO1,SH3BP4,STEAP2,DNM2,CD9,ECE1,RAB27B,FZD5,GAD1,NRGN,DVL2 |
| 4.620e-02 | -3.07 | protein localization to organelle | biological process | GO:0033365 | 546 | 96 | 16441 | 2455 |
SUN1,LAMP1,TP53,TRAPPC8,STIL,BCAP31,ZFYVE9,TTC21B,ZFYVE16,ACAP2,ARL1,BCL6,SMO,TNPO2,SNX16,RPN2,TRAM1,F2R,SNX10,PLK1,SEC61B,CENPA,AKT1,SYNE2,KDELR3,ARFRP1,PYGO1,AURKB,CDK1,DAG1,ARF4,OPTN,PEX5,DDOST,DNM1L,GNPTAB,PEX2,CHMP4B,KPNA2,ARF6,RPL22,CNEP1R1,PINK1,PACSIN2,SEC61G,PEX6,SOX9,PDIA3,RAB6A,SPDL1,TSPAN17,AIP,SIX4,LMNA,CALR,RB1,RNF128,PPP1R10,BMP7,RPL39,FBXO7,BAX,SRP54,SORL1,H2AFY,PIKFYVE,SYK,NUP85,KDELR1,NAGPA,SUN2,GCC2,PMPCB,HES1,PIK3R1,PRICKLE1,KIF20B,RAB3IP,BBS2,RGPD5,SCARB2,RPL12,HTT,TIMM8A,TMEM30A,NFKBIA,SH3BP4,FAM83D,AURKA,SPCS3,CD81,JAK3,TOB1,RAD21,EHD1,DRD1 |
| 4.623e-02 | -3.07 | copper ion transmembrane transporter activity | molecular function | GO:0005375 | 6 | 3 | 16491 | 2452 |
SLC11A2,SLC31A2,ATP7B |
| 4.623e-02 | -3.07 | phosphatidylinositol trisphosphate phosphatase activity | molecular function | GO:0034594 | 6 | 3 | 16491 | 2452 |
PTEN,INPP5D,INPP4B |
| 4.623e-02 | -3.07 | DNA insertion or deletion binding | molecular function | GO:0032135 | 6 | 3 | 16491 | 2452 |
PCNA,MSH6,MSH2 |
| 4.623e-02 | -3.07 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides | molecular function | GO:0016812 | 6 | 3 | 16491 | 2452 |
OPLAH,AMDHD1,DPYSL2 |
| 4.623e-02 | -3.07 | MutLalpha complex binding | molecular function | GO:0032405 | 6 | 3 | 16491 | 2452 |
PCNA,MSH6,MSH2 |
| 4.623e-02 | -3.07 | Vascular smooth muscle contraction | KEGG pathways | ko04270 | 120 | 26 | 6908 | 1076 |
MYL9,PLA2G4A,RHOA,PPP1R12A,ARHGEF11,CALM1,CALM3,CALCRL,PRKCQ,ITPR2,ITPR3,PRKACA,GNA11,EDNRA,GNAS,CALM2,KCNMB4,CALD1,MYLK,ITPR1,PRKG1,ACTA2,PPP1CB,CACNA1D,PPP1CA,PLCB2 |
| 4.623e-02 | -3.07 | Vascular smooth muscle contraction | KEGG pathways | hsa04270 | 120 | 26 | 6908 | 1076 |
MYL9,PLA2G4A,RHOA,PPP1R12A,ARHGEF11,CALM1,CALM3,CALCRL,PRKCQ,ITPR2,ITPR3,PRKACA,GNA11,EDNRA,GNAS,CALM2,KCNMB4,CALD1,MYLK,ITPR1,PRKG1,ACTA2,PPP1CB,CACNA1D,PPP1CA,PLCB2 |
| 4.627e-02 | -3.07 | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | WikiPathways | WP732 | 17 | 6 | 4455 | 729 |
ELK4,MAPKAPK2,RASGRF1,ELK1,ITPR1,RASGRP1 |
| 4.630e-02 | -3.07 | V$PTF1BETA_Q6 | MSigDB lists | V$PTF1BETA_Q6 | 223 | 42 | 17758 | 2588 |
CCNC,LRRFIP2,ARMCX3,IGFBP6,THRA,SLC25A13,FHDC1,CD274,BCL2L1,APBA1,DHRS3,XPR1,MECOM,FOXP2,PHYHIP,KCTD15,FAM46A,LRRN2,CALD1,SLC44A1,CAPG,TFAP2A,ERBB3,TBC1D10B,SMARCA2,CASK,EMP3,ROR1,TMTC2,ICMT,NPDC1,RASA1,CAMK2N2,SYT7,H1F0,ITGA7,AMMECR1,PIAS2,NR4A3,NR4A2,ATP1B3,STARD13 |
| 4.631e-02 | -3.07 | chemorepellent activity | molecular function | GO:0045499 | 28 | 8 | 16491 | 2452 |
SEMA6B,SEMA4D,FLRT3,NRG1,EFNA5,SEMA3G,SEMA3A,SEMA3B |
| 4.631e-02 | -3.07 | Wnt-protein binding | molecular function | GO:0017147 | 28 | 8 | 16491 | 2452 |
CTHRC1,FZD4,SMO,TRABD2A,ROR1,FZD5,FZD7,FZD6 |
| 4.631e-02 | -3.07 | S-acyltransferase activity | molecular function | GO:0016417 | 28 | 8 | 16491 | 2452 |
ZDHHC12,ZDHHC20,ZDHHC13,ZDHHC23,ZDHHC7,ZDHHC3,ZDHHC21,DLAT |
| 4.633e-02 | -3.07 | GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN | 169 | 33 | 17758 | 2588 |
DDX58,IL15RA,HAPLN3,ESRP1,TAP1,SOD2,HERC5,EGR3,SLC1A3,OSR2,HERC6,OTUD1,FAM111A,ITGB8,PIK3AP1,IQCD,SELK,IFIT1,CITED2,SUN2,KIF20A,PAPD7,CYS1,IFIT3,DGKE,SOCS3,PTGS2,TDRD7,NR4A3,HS3ST3B1,SHROOM2,IFIH1,CPEB2 |
| 4.634e-02 | -3.07 | cilium morphogenesis | biological process | GO:0060271 | 206 | 40 | 16441 | 2455 |
TTC8,CFAP74,TCTN2,AK7,POC1B,C5orf30,RAB23,CCNO,ZMYND10,STIL,SSX2IP,TTC21B,LRRC6,OCRL,DNM2,SNX10,RPGR,TTLL1,DNAAF3,DNAI1,SPEF2,CELSR2,CFAP46,CEP89,B9D2,FOPNL,RAB3IP,NPHP3,BBS2,SPAG1,DZIP1L,CEP162,ONECUT1,TRAF3IP1,WDR19,WWTR1,CEP41,CFAP20,ATMIN,EHD1 |
| 4.634e-02 | -3.07 | regulation of calcium ion transport | biological process | GO:0051924 | 206 | 40 | 16441 | 2455 |
LGALS3,UBASH3B,CACNA2D2,CALM3,P2RX7,PRKACA,CACNB4,PDGFB,ICAM1,CALM2,CTNNB1,GNB5,STIM1,CABP1,PLCG2,BAX,TRPC1,TSPAN13,PDE4D,CACNA1D,F2R,HSPA2,CAMK2G,MYO5A,P2RX4,RHOA,CASK,CALM1,ATP1B1,PLCG1,PTGS2,HTT,WFS1,MYLK,SARAF,PKD2,GPER1,TRPC3,JAK3,DRD1 |
| 4.635e-02 | -3.07 | human chr1p34.1 | chromosome location | human chr1p34.1 | 52 | 10 | 26250 | 2805 |
CCDC24,RNF220,ZSWIM5,ARTN,CDC20,BTBD19,CTPS1,KIF2C,POMGNT1,TSPAN1 |
| 4.638e-02 | -3.07 | PLK2 and PLK4 events | Pathway Interaction DB | plk2_4pathway | 2 | 2 | 2227 | 480 |
PLK2,PLK4 |
| 4.638e-02 | -3.07 | E-cadherin signaling events | Pathway Interaction DB | ecadherin_1_pathway | 2 | 2 | 2227 | 480 |
CDH1,CTNNB1 |
| 4.647e-02 | -3.07 | LEIN_CHOROID_PLEXUS_MARKERS | MSigDB lists | LEIN_CHOROID_PLEXUS_MARKERS | 99 | 21 | 17758 | 2588 |
COL9A3,ACACB,PCOLCE,FZD4,ELOVL7,SYNE2,EZR,GGH,NOTCH2,STEAP1,LEPR,LGALS3BP,TCN2,RBM47,CTSC,SPINT2,STEAP2,CDH3,ACAD8,CSRP2,EPHX1 |
| 4.647e-02 | -3.07 | GOLGI_APPARATUS_PART | MSigDB lists | GOLGI_APPARATUS_PART | 99 | 21 | 17758 | 2588 |
B3GALT6,QSOX1,GOLIM4,COG2,FURIN,TGOLN2,CHST2,SLC9A7,GNAS,DOPEY2,TAPBP,ENTPD4,LDLRAP1,STX10,DNM1L,OCRL,NECAB3,ATP7B,STEAP2,LMAN1,GOLGB1 |
| 4.655e-02 | -3.07 | dense core granule | cellular component | GO:0031045 | 10 | 4 | 17570 | 2579 |
SOD1,MYRIP,SYT7,NCS1 |
| 4.660e-02 | -3.07 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_DN | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_DN | 181 | 35 | 17758 | 2588 |
NFKBIE,TRIP10,ATP9A,INPP5D,STRN4,EFHD2,AES,SH2D4A,ZNF212,CALR,VASP,RPS6KA2,SRPX,SP100,CST3,TRIM21,TAGLN2,SEMA3G,CTTN,PXMP4,NTN1,GFI1,ENPP4,SGCE,C3orf52,SPA17,COX11,ROR1,CDC25C,DDX23,SOCS3,TWSG1,CANT1,NRBP1,DRD1 |
| 4.660e-02 | -3.07 | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | 181 | 35 | 17758 | 2588 |
GAA,CCDC109B,APOO,RET,NDRG2,VASH1,PHF1,BCAP31,VASP,TGFBR3,ANKS1B,CTSC,GLB1L2,SEMA3G,SCN3A,TDP1,ELK3,CTNNAL1,SLC39A8,DIAPH2,ENDOD1,TSC1,PLEKHG6,TRAM2,KLF12,SLC4A4,FAT4,PVRL2,TMC5,CLIP4,GRIN2D,NRBP1,RPS6KA3,DOCK9,PHC1 |
| 4.660e-02 | -3.07 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_DN | 181 | 35 | 17758 | 2588 |
TAOK2,ARAP3,REPS2,STRN4,IL27RA,NENF,CCNL1,OSR2,DPP8,FANCI,PER2,WWP2,ZNF432,PPP1R10,MEGF8,DDHD2,KANK3,SCYL3,TUBA4A,CERS2,ZNF84,ASXL1,SCRIB,ZFAND5,ARF4,DUOX1,MID1IP1,KCNK1,PSMD3,TMC5,CAB39,KPNA2,CENPE,ATP6V1C1,MELK |
| 4.662e-02 | -3.07 | acute_leukaemic_transformation_of_myeloproliferative_neoplasm | COSMIC cancer mutations | acute_leukaemic_transformation_of_myeloproliferative_neoplasm | 44 | 11 | 17775 | 2585 |
CALR,JAK1,AKT1,ASXL1,GATA2,PTEN,TP53,CBL,IDH1,FLT3,JAK3 |
| 4.662e-02 | -3.07 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_myeloproliferative_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_myeloproliferative_neoplasm | 44 | 11 | 17775 | 2585 |
CALR,JAK1,AKT1,ASXL1,GATA2,PTEN,TP53,CBL,IDH1,FLT3,JAK3 |
| 4.663e-02 | -3.07 | MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MSigDB lists | MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 205 | 39 | 17758 | 2588 |
PLEKHG3,BMF,CDH22,CAMKK1,NDRG1,GNAL,BIK,RET,CCNO,FAM78A,KCNC4,FGF19,CDS1,ADORA1,ITGA3,A4GALT,KNDC1,MAP3K9,TFAP2A,RAB20,ERBB3,GAD1,MYRIP,TUBA4A,RASGRF1,ADAMTS2,PTPRU,PTGER4,KDELR3,SNTB1,PTGFRN,ABLIM2,STX3,KCNK1,ATP7B,P4HA2,TSPAN18,NXPH4,OCLN |
| 4.667e-02 | -3.06 | GSE360_DC_VS_MAC_M_TUBERCULOSIS_UP | MSigDB lists | GSE360_DC_VS_MAC_M_TUBERCULOSIS_UP | 187 | 36 | 17758 | 2588 |
KIF3C,TAOK2,MRC2,TXN,AGRN,S100A11,PSME2,CUL1,HMGN3,DUSP5,NRP2,PSMD1,CDH1,CTSC,RRBP1,AKR1B1,OSTF1,IFIT1,SULT2B1,PSMA5,MX1,PLK1,SOD1,ARAP2,SEC61B,CENPA,PTGER4,COL7A1,IFIT3,CCNF,CD83,DDAH1,TIMP3,GLA,TRAF5,IRF1 |
| 4.667e-02 | -3.06 | GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP | 187 | 36 | 17758 | 2588 |
SUN1,LASP1,PCOLCE,TMEM184B,SSH1,MPZL1,ERBB2,BLCAP,BCL2L1,VASH1,SEPP1,PDIA4,CTNNBIP1,CTNNB1,CD9,ARVCF,SRP54,TLN2,F2R,SMYD5,PPIF,RHOA,DCHS1,KDELR3,KIAA1109,BLVRA,SNTB1,IDH1,PDHX,TRAM2,ALDH3B1,PRCP,PPM1H,DTX4,APBA2,LTA4H |
| 4.667e-02 | -3.06 | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP | 187 | 36 | 17758 | 2588 |
FARP1,CHCHD7,PPM1J,DHPS,TMX4,NDRG2,IL13RA1,MGST2,ELMOD2,SLC25A35,MARCH8,FAM111A,METTL7A,PCYOX1,SGK1,IL17RA,C10orf54,SGCB,NDUFA12,CRTAP,COX11,ERBB2IP,PDK3,ICMT,SLC25A5,ADRBK2,ZNF641,FA2H,STX10,ABHD12,PRCP,NRGN,LTA4H,RTN3,KLF7,CD33 |
| 4.667e-02 | -3.06 | AAANWWTGC_UNKNOWN | MSigDB lists | AAANWWTGC_UNKNOWN | 187 | 36 | 17758 | 2588 |
SORT1,PAX6,GATA3,HOXB2,DTX3L,TFAP4,FOXP2,PPP1R10,SHC3,GPC3,PHTF1,STEAP2,BCL6,CACNA1D,NTN1,CITED2,TRAM1,ITM2C,DUSP1,DPYSL5,ZNF462,TGIF1,TBC1D8B,DSTN,ATP1B1,PCTP,FZD7,SOX13,MAN2A2,KLF12,FGFR2,MYLK,EFNA5,EIF4EBP2,PRIMA1,DIS3L |
| 4.669e-02 | -3.06 | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDM_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDM_UP | 193 | 37 | 17758 | 2588 |
WASF3,EPAS1,PARP14,TBC1D1,PBX3,NES,DNAJB11,NOTCH2,B4GALT4,KREMEN1,ICAM1,ZFX,AKR1B1,H2AFY,BRI3,PIM1,TFG,IL1RAP,PPIF,CASK,RUNX3,TANC1,FNDC3A,IFIT3,STX3,CD83,HLA-B,TMEM50B,MPRIP,RND3,C19orf66,PLK2,NAT1,ITGAV,RELL1,NRBP1,STARD3NL |
| 4.669e-02 | -3.06 | GSE360_CTRL_VS_L_DONOVANI_MAC_UP | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_MAC_UP | 193 | 37 | 17758 | 2588 |
CCNI,DAP,TMX4,BLCAP,VASH1,GSTP1,RABGGTA,PPP1R10,STIM1,ATP5H,GPC3,PLCG2,NEK2,ADAM15,PPP1CA,PCCB,ZWINT,PSMB4,GUSB,PTPRU,PARP4,CDA,BTN3A2,ESYT1,BCL7B,SLC25A5,GNA11,MAPKAPK2,FUCA1,NUCB1,TAPBP,H1F0,STK38,PIAS2,PLXND1,PDXK,USF2 |
| 4.669e-02 | -3.06 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN | 193 | 37 | 17758 | 2588 |
FAM171B,SLC2A8,MCTP2,ASB9,GMPR,FAM101B,IL18R1,DENND2D,LGALS3BP,RASSF8,TGFBR3,KCNK5,SORL1,FAM102A,STEAP3,CNGA1,KANK3,SLC16A5,CCDC88A,MBP,PLSCR1,SNTB2,LITAF,PDE5A,RUNX3,TCF7,FXR2,RNF19B,CASP4,CDK5R1,RHOB,ABLIM2,KCNMB4,CGREF1,DYSF,HS3ST3B1,SAT2 |
| 4.669e-02 | -3.06 | GSE17721_0.5H_VS_24H_CPG_BMDM_UP | MSigDB lists | GSE17721_0.5H_VS_24H_CPG_BMDM_UP | 193 | 37 | 17758 | 2588 |
CCDC109B,S100A11,ITGA6,EPS8,NANS,SEPT4,ZYX,SPP1,NOV,OXCT1,SH3BP1,PPP4R1,ABCD1,TMEM37,ETHE1,PLCB2,NDUFA12,S100A6,GCNT1,CENPA,TIMP2,LAP3,SEPT6,PYGL,EZR,TNS1,NFIX,NAAA,TIMM8A,DOLPP1,NR4A3,CHMP4B,RGS14,MYL12B,RAB3IL1,RPS6KA3,JARID2 |
| 4.669e-02 | -3.06 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP | 193 | 37 | 17758 | 2588 |
OTUD5,BIN1,COL9A3,BMF,TRIM24,DGKQ,SELL,APPBP2,RAC2,CD22,LMO4,HLA-C,PXMP4,ALS2CL,RASGRP1,SMAGP,SMC4,B3GNT2,ING1,CR2,SESN1,RASA1,BTG1,MSL1,KCNK1,FAAH,CCDC6,STK38,MMP17,MADD,SH3GLB2,NFKBIZ,IRF7,SP6,ATP1B3,SNX30,KLF7 |
| 4.669e-02 | -3.06 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 193 | 37 | 17758 | 2588 |
UGT8,TMEM184B,NFKBIE,AASS,DAP,ETV5,TAP1,NDRG2,IL18,GDF15,BAHD1,VASH1,SEPP1,HOXB2,LGALS3BP,PDIA4,ATG4A,RASSF8,CTGF,SH3BP1,ABCA2,CD9,FLOT2,F2R,NAGA,RHOA,BLVRA,ALDH3B1,PRCP,PPP2R4,PPM1H,INPP4B,IRF7,LTA4H,IRF1,EHD1,CD33 |
| 4.669e-02 | -3.06 | VESICLE_MEDIATED_TRANSPORT | MSigDB lists | VESICLE_MEDIATED_TRANSPORT | 193 | 37 | 17758 | 2588 |
ARAP3,ARFGEF1,SYTL4,SYTL2,M6PR,ZFYVE16,NAPG,DOPEY2,AP1M2,ADORA1,GATA2,LMAN2L,STEAP2,PRKCI,SORL1,CPLX1,TINAGL1,LMAN1,TMX1,SEC23A,KIF20A,COG2,VAMP3,VPS4B,KIF1C,AKAP3,CBL,RHOB,MAPK8IP1,OPTN,LDLRAP1,CORO1C,SH3BP4,PLIN3,ARF6,NRBP1,ABCA1 |
| 4.669e-02 | -3.06 | GSE17721_LPS_VS_PAM3CSK4_1H_BMDM_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_1H_BMDM_DN | 193 | 37 | 17758 | 2588 |
SORT1,TRIM2,PARP12,LFNG,FRMD6,SLC41A1,NDRG1,RASA2,ASL,ICAM1,NAPG,PPP1R10,GATA2,FAM20C,KLC3,PIK3CA,TMBIM6,CD70,CADPS2,DGKG,B3GNT2,TRIM8,PLSCR1,TNIP1,TBC1D8B,NR4A1,PIM3,CDK5R1,FAS,IL1R1,PTGS2,NFKBIA,TDRD7,ARRDC1,GLB1,NFKBIZ,CBX4 |
| 4.669e-02 | -3.06 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 193 | 37 | 17758 | 2588 |
MAN2B2,KIF3C,TCF25,TMEM184B,ST14,DAP,ADO,BLVRB,NDRG2,CRABP2,RPS6KA2,ITGA3,GNB5,GPC3,PLCG2,AKR1B1,VAT1,PIM1,CTTN,ALDH3A2,EEF1D,SUN2,DDB2,SEC61B,CDA,FXR2,NMT2,CD83,BCAR3,IL1R1,FUCA1,RPL12,PRCP,GLB1,SERPINB6,LTA4H,GAB1 |
| 4.673e-02 | -3.06 | receptor complex | cellular component | GO:0043235 | 325 | 59 | 17570 | 2579 |
SORBS1,TAOK2,ACVR1,GRIK2,ITGA6,TRAF2,EPS8,RET,GABRG2,ERBB2,TGFBR1,IL13RA1,ITPR2,PLXNA1,NOTCH2,DDR1,AIP,ITGA2B,NRP2,BMP2,TGFBR3,ITGA3,ITGB8,IRAK1,IGF1R,NPNT,IL6ST,DLG1,TRPC1,NOTCH3,ERBB3,DLG3,IL10RB,SYK,ACVR1C,GRIN1,CR2,ROR1,ITPR3,CD40,ALCAM,LEPR,EGFR,BCL10,AHRR,GABRD,CD8A,INSR,ABHD12,ITGA7,NETO2,OSMR,GRIN2D,ITGAV,PLXND1,TRAF5,NR3C2,AHR,LIFR |
| 4.675e-02 | -3.06 | regulation of cilium movement involved in cell motility | biological process | GO:0060295 | 6 | 3 | 16441 | 2455 |
CFAP20,BBS2,CCSAP |
| 4.675e-02 | -3.06 | negative regulation of dendritic spine morphogenesis | biological process | GO:0061002 | 6 | 3 | 16441 | 2455 |
EFNA1,PTEN,NGEF |
| 4.675e-02 | -3.06 | negative regulation of striated muscle contraction | biological process | GO:0045988 | 6 | 3 | 16441 | 2455 |
PDE5A,ADORA1,ADRBK1 |
| 4.675e-02 | -3.06 | negative regulation of anion transmembrane transport | biological process | GO:1903960 | 6 | 3 | 16441 | 2455 |
IRS2,ANO9,AKT1 |
| 4.675e-02 | -3.06 | ectodermal cell differentiation | biological process | GO:0010668 | 6 | 3 | 16441 | 2455 |
ETS2,ITGA6,ELF5 |
| 4.675e-02 | -3.06 | paranodal junction assembly | biological process | GO:0030913 | 6 | 3 | 16441 | 2455 |
CNTNAP1,UGT8,CD9 |
| 4.675e-02 | -3.06 | pericyte cell differentiation | biological process | GO:1904238 | 6 | 3 | 16441 | 2455 |
ACTA2,OSR1,PDGFB |
| 4.675e-02 | -3.06 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | GO:0045869 | 6 | 3 | 16441 | 2455 |
APOBEC3H,APOBEC3D,APOBEC3G |
| 4.675e-02 | -3.06 | regulation of antimicrobial peptide production | biological process | GO:0002784 | 6 | 3 | 16441 | 2455 |
KLK7,KLK5,NOD2 |
| 4.675e-02 | -3.06 | negative regulation of membrane protein ectodomain proteolysis | biological process | GO:0051045 | 6 | 3 | 16441 | 2455 |
TIMP2,TIMP3,TIMP1 |
| 4.675e-02 | -3.06 | hair follicle placode formation | biological process | GO:0060789 | 6 | 3 | 16441 | 2455 |
GNAS,HDAC1,CTNNB1 |
| 4.675e-02 | -3.06 | 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process | biological process | GO:0050428 | 6 | 3 | 16441 | 2455 |
PAPSS2,SLC35B3,PAPSS1 |
| 4.675e-02 | -3.06 | positive regulation of antibacterial peptide production | biological process | GO:0002803 | 6 | 3 | 16441 | 2455 |
KLK7,KLK5,NOD2 |
| 4.675e-02 | -3.06 | purine ribonucleoside bisphosphate biosynthetic process | biological process | GO:0034036 | 6 | 3 | 16441 | 2455 |
PAPSS2,SLC35B3,PAPSS1 |
| 4.675e-02 | -3.06 | positive regulation of antimicrobial peptide production | biological process | GO:0002225 | 6 | 3 | 16441 | 2455 |
KLK7,KLK5,NOD2 |
| 4.675e-02 | -3.06 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | biological process | GO:1901620 | 6 | 3 | 16441 | 2455 |
PRKACA,TRAF3IP1,GPR161 |
| 4.675e-02 | -3.06 | regulation of cilium-dependent cell motility | biological process | GO:1902019 | 6 | 3 | 16441 | 2455 |
CFAP20,BBS2,CCSAP |
| 4.675e-02 | -3.06 | leucine metabolic process | biological process | GO:0006551 | 6 | 3 | 16441 | 2455 |
HMGCL,MCCC2,MCCC1 |
| 4.675e-02 | -3.06 | positive regulation of cell aging | biological process | GO:0090343 | 6 | 3 | 16441 | 2455 |
SIRT1,HMGA1,LMNA |
| 4.675e-02 | -3.06 | negative regulation of cholesterol storage | biological process | GO:0010887 | 6 | 3 | 16441 | 2455 |
ABCA1,ABCG1,PPARA |
| 4.675e-02 | -3.06 | cellular triglyceride homeostasis | biological process | GO:0035356 | 6 | 3 | 16441 | 2455 |
SIRT1,SLC25A27,DGAT2 |
| 4.675e-02 | -3.06 | positive regulation of synaptic transmission, dopaminergic | biological process | GO:0032226 | 6 | 3 | 16441 | 2455 |
PINK1,RAB3B,FLOT1 |
| 4.675e-02 | -3.06 | positive regulation of fibroblast apoptotic process | biological process | GO:2000271 | 6 | 3 | 16441 | 2455 |
BTG1,STK17B,STK17A |
| 4.675e-02 | -3.06 | regulation of antibacterial peptide production | biological process | GO:0002786 | 6 | 3 | 16441 | 2455 |
KLK7,KLK5,NOD2 |
| 4.675e-02 | -3.06 | positive regulation of integrin-mediated signaling pathway | biological process | GO:2001046 | 6 | 3 | 16441 | 2455 |
CD63,EMP2,DMTN |
| 4.675e-02 | -3.06 | regulation of cilium beat frequency involved in ciliary motility | biological process | GO:0060296 | 6 | 3 | 16441 | 2455 |
CFAP20,BBS2,CCSAP |
| 4.675e-02 | -3.06 | activation-induced cell death of T cells | biological process | GO:0006924 | 6 | 3 | 16441 | 2455 |
AKT1,SIVA1,FAS |
| 4.675e-02 | -3.06 | conditioned taste aversion | biological process | GO:0001661 | 6 | 3 | 16441 | 2455 |
FOS,GRIN1,DRD1 |
| 4.675e-02 | -3.06 | response to UV-A | biological process | GO:0070141 | 6 | 3 | 16441 | 2455 |
CCND1,AKT1,EGFR |
| 4.675e-02 | -3.06 | cytoplasmic pattern recognition receptor signaling pathway in response to virus | biological process | GO:0039528 | 6 | 3 | 16441 | 2455 |
DDX58,IRF7,IFIH1 |
| 4.675e-02 | -3.06 | plasma membrane raft assembly | biological process | GO:0044854 | 6 | 3 | 16441 | 2455 |
PACSIN2,EMP2,FLOT1 |
| 4.675e-02 | -3.06 | DNA cytosine deamination | biological process | GO:0070383 | 6 | 3 | 16441 | 2455 |
APOBEC3H,APOBEC3D,APOBEC3G |
| 4.675e-02 | -3.06 | positive regulation of protein glycosylation | biological process | GO:0060050 | 6 | 3 | 16441 | 2455 |
IL15,ARFGEF1,CHP1 |
| 4.675e-02 | -3.06 | mesangial cell differentiation | biological process | GO:0072007 | 6 | 3 | 16441 | 2455 |
ACTA2,OSR1,PDGFB |
| 4.675e-02 | -3.06 | renal vesicle formation | biological process | GO:0072033 | 6 | 3 | 16441 | 2455 |
CTNNB1,FMN1,SMO |
| 4.675e-02 | -3.06 | copper ion transmembrane transport | biological process | GO:0035434 | 6 | 3 | 16441 | 2455 |
SLC11A2,SLC31A2,ATP7B |
| 4.675e-02 | -3.06 | regulation of gamma-delta T cell differentiation | biological process | GO:0045586 | 6 | 3 | 16441 | 2455 |
EGR3,SYK,SOX13 |
| 4.675e-02 | -3.06 | flavin-containing compound metabolic process | biological process | GO:0042726 | 6 | 3 | 16441 | 2455 |
ENPP1,RFK,VCP |
| 4.675e-02 | -3.06 | mitral valve morphogenesis | biological process | GO:0003183 | 6 | 3 | 16441 | 2455 |
TWIST1,EFNA1,ACVR1 |
| 4.675e-02 | -3.06 | locomotion involved in locomotory behavior | biological process | GO:0031987 | 6 | 3 | 16441 | 2455 |
RCAN2,FZD4,MYO5A |
| 4.675e-02 | -3.06 | plasma membrane raft organization | biological process | GO:0044857 | 6 | 3 | 16441 | 2455 |
PACSIN2,EMP2,FLOT1 |
| 4.675e-02 | -3.06 | negative regulation of fat cell proliferation | biological process | GO:0070345 | 6 | 3 | 16441 | 2455 |
GATA2,PER2,E2F1 |
| 4.686e-02 | -3.06 | SIRT3 (sirtuin 3) | protein interactions | 23410 | 31 | 9 | 16036 | 2547 |
GRN,PEX5,HSP90B1,DNM1L,SBF1,LSM14B,SNTB1,PGAP1,ARHGEF26 |
| 4.686e-02 | -3.06 | ABAT (4-aminobutyrate aminotransferase) | protein interactions | 18 | 31 | 9 | 16036 | 2547 |
PGM1,ALDH5A1,LGR4,DSTN,SOD2,AKR1B1,ALDH7A1,PDXK,FAH |
| 4.686e-02 | -3.06 | RASSF7 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 7) | protein interactions | 8045 | 31 | 9 | 16036 | 2547 |
CEP97,CCDC6,GNPTAB,FRMD6,PPP1CB,PPP1CA,CTSD,PICK1,CCDC88A |
| 4.689e-02 | -3.06 | MODULE_433 | MSigDB lists | MODULE_433 | 60 | 14 | 17758 | 2588 |
MDK,BMP2,PDGFA,NOV,IL15,AREG,CSF1,BMP7,BMP1,NRG2,NRG1,PDGFB,TNFSF9,S100A6 |
| 4.689e-02 | -3.06 | PID_FCER1_PATHWAY | MSigDB lists | PID_FCER1_PATHWAY | 60 | 14 | 17758 | 2588 |
PLA2G4A,PLCG1,FYN,AKT1,INPP5D,PAK2,PIK3R1,PIK3CA,PLD2,CBL,FOS,SYK,RASA1,DUSP1 |
| 4.689e-02 | -3.06 | TTGCWCAAY_V$CEBPB_02 | MSigDB lists | TTGCWCAAY_V$CEBPB_02 | 60 | 14 | 17758 | 2588 |
PITX2,BMF,DCAF6,CITED4,NFKBIE,PRDX3,KLF5,ITPR3,IDH1,DENND2D,TOB1,CKAP4,NRP2,RHOB |
| 4.689e-02 | -3.06 | CAFFAREL_RESPONSE_TO_THC_24HR_5_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_24HR_5_DN | 60 | 14 | 17758 | 2588 |
CALM2,MRPS33,FOXM1,FXYD3,SPINT2,CALM1,RANBP1,MCCC1,CALM3,NUSAP1,ALG2,UBE2C,CDK1,ARF4 |
| 4.690e-02 | -3.06 | regulation of osteoblast differentiation | biological process | GO:0045667 | 108 | 23 | 16441 | 2455 |
CTHRC1,RUNX2,ACVR1,WNT10B,ILK,PRKACA,CTNNBIP1,GNAS,BMP2,CTNNB1,CYR61,NPNT,SEMA4D,AREG,FAM20C,TWSG1,FGFR2,IL6ST,BMP7,SUCO,PIAS2,TWIST1,TOB1 |
| 4.690e-02 | -3.06 | RAF-independent MAPK1/3 activation | REACTOME pathways | R-HSA-112409 | 23 | 7 | 8202 | 1235 |
DUSP10,DUSP4,JAK1,CDK1,IL6ST,DUSP5,DUSP1 |
| 4.698e-02 | -3.06 | phosphatidylinositol-3,4,5-trisphosphate binding | molecular function | GO:0005547 | 33 | 9 | 16491 | 2452 |
ZFYVE16,ARAP2,ARAP3,AKT1,IQGAP1,ARAP1,RACGAP1,FAM21C,NRGN |
| 4.702e-02 | -3.06 | PPP2R1B (protein phosphatase 2, regulatory subunit A, beta) | protein interactions | 5519 | 86 | 20 | 16036 | 2547 |
MOB4,SERTAD4,PRKAA1,ZNF219,CDK1,EGFR,ZNF114,PDCD10,PPP2R5A,BHLHE41,DAPK1,HDAC1,CRY2,ACADM,UNC5B,WNT3A,ZRANB1,SGOL1,PPP2R2D,PPP2R5D |
| 4.703e-02 | -3.06 | zf-DHHC | pfam domains | PF01529 | 23 | 7 | 16629 | 2504 |
ZDHHC7,ZDHHC12,ZDHHC3,ZDHHC20,ZDHHC13,ZDHHC21,ZDHHC23 |
| 4.703e-02 | -3.06 | EF-hand_5 | pfam domains | PF13202 | 23 | 7 | 16629 | 2504 |
RCN1,GCA,CAPNS1,RASGRP3,NECAB3,SDF4,RASGRP2 |
| 4.703e-02 | -3.06 | Spectrin | pfam domains | PF00435 | 23 | 7 | 16629 | 2504 |
SPTBN5,DRP2,SYNE3,SPTB,MCF2L,SYNE2,UTRN |
| 4.703e-02 | -3.06 | Fz | pfam domains | PF01392 | 23 | 7 | 16629 | 2504 |
COL18A1,ROR1,FZD5,FZD4,FZD7,FZD6,SMO |
| 4.704e-02 | -3.06 | FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN | MSigDB lists | FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN | 71 | 16 | 17758 | 2588 |
SPEF2,RUNX3,SYP,CD274,CBL,PICK1,ZNF275,MFAP3L,MLPH,IRAK1,MATN2,PLCG2,CABIN1,TWIST1,PTGES,CD33 |
| 4.705e-02 | -3.06 | salivary_gland-carcinoma-adenocarcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-adenocarcinoma | 19 | 6 | 17775 | 2585 |
ERBB2,CTNNB1,PTEN,EGFR,PIK3CA,TP53 |
| 4.705e-02 | -3.06 | bone-sacrum-chordoma | COSMIC cancer mutations | bone-sacrum-chordoma | 19 | 6 | 17775 | 2585 |
CTNNB1,FLT3,PTEN,EGFR,PIK3CA,TP53 |
| 4.705e-02 | -3.06 | cerebral_cortex | COSMIC cancer mutations | cerebral_cortex | 19 | 6 | 17775 | 2585 |
TSC1,IDH1,PTEN,MSH6,MSH2,TP53 |
| 4.705e-02 | -3.06 | gliosarcoma | COSMIC cancer mutations | gliosarcoma | 19 | 6 | 17775 | 2585 |
CDKN2C,CTNNB1,IDH1,PTEN,PIK3CA,TP53 |
| 4.705e-02 | -3.06 | NS-carcinoma-adenocarcinoma | COSMIC cancer mutations | NS-carcinoma-adenocarcinoma | 19 | 6 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA |
| 4.705e-02 | -3.06 | supratentorial | COSMIC cancer mutations | supratentorial | 19 | 6 | 17775 | 2585 |
CTNNB1,IDH1,PTEN,EGFR,SMO,TP53 |
| 4.705e-02 | -3.06 | small_intestine-ileum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-ileum-carcinoma-adenocarcinoma | 19 | 6 | 17775 | 2585 |
GNAS,ERBB2,CTNNB1,IDH1,PIK3CA,TP53 |
| 4.713e-02 | -3.05 | arachidonic acid metabolic process | biological process | GO:0019369 | 64 | 15 | 16441 | 2455 |
PLA2G4A,MAPKAPK2,PTGS2,FAM213B,CYP1A1,FAAH,CYP2J2,CYP2S1,CYP2U1,LTA4H,CYP4F3,PTGES,CYP1B1,GPX4,ABCC1 |
| 4.713e-02 | -3.05 | leukocyte homeostasis | biological process | GO:0001776 | 64 | 15 | 16441 | 2455 |
CASP3,AKT1,SIVA1,RC3H2,BAX,P2RX7,PPP2R3C,PIK3CD,PKN1,RAG1,FLT3,CCNB2,JAK3,FAS,MECOM |
| 4.713e-02 | -3.05 | regulation of stress fiber assembly | biological process | GO:0051492 | 64 | 15 | 16441 | 2455 |
TSC1,BAG4,RHOA,NF2,CTGF,LIMK1,PIK3R1,SDC4,PTGER4,ARAP1,RGCC,SORBS3,PRKCQ,TACSTD2,EPHA1 |
| 4.715e-02 | -3.05 | Vif-mediated degradation of APOBEC3G | REACTOME pathways | R-HSA-180585 | 53 | 13 | 8202 | 1235 |
PSMD1,PSMB4,TCEB2,PSME2,PSMD3,PSMC2,PSMD7,PSMD10,PSME1,PSMC1,APOBEC3G,PSMA4,PSMA5 |
| 4.718e-02 | -3.05 | dermatan sulfate biosynthesis | BIOCYC pathways | META_PWY-6571 | 15 | 6 | 907 | 172 |
CHSY3,DSE,XYLT2,XYLT1,CSGALNACT1,CHPF |
| 4.718e-02 | -3.05 | D-myo-inositol (1,3,4)-trisphosphate biosynthesis | BIOCYC pathways | HUMAN_PWY-6364 | 15 | 6 | 907 | 172 |
INPPL1,ITPKA,MINPP1,PTEN,OCRL,INPP5D |
| 4.718e-02 | -3.05 | D-myo-inositol (1,3,4)-trisphosphate biosynthesis | BIOCYC pathways | META_PWY-6364 | 15 | 6 | 907 | 172 |
INPPL1,ITPKA,MINPP1,PTEN,OCRL,INPP5D |
| 4.718e-02 | -3.05 | dermatan sulfate biosynthesis | BIOCYC pathways | HUMAN_PWY-6571 | 15 | 6 | 907 | 172 |
CHSY3,DSE,XYLT2,XYLT1,CSGALNACT1,CHPF |
| 4.723e-02 | -3.05 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | MSigDB lists | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | 44 | 11 | 17758 | 2588 |
ADD1,WIPI1,DNAJC3,WFS1,PDIA5,KDELR3,DNAJB11,PDIA6,CTDSP2,LMNA,DNAJB9 |
| 4.723e-02 | -3.05 | GCM_LTK | MSigDB lists | GCM_LTK | 44 | 11 | 17758 | 2588 |
HSF4,PLK1,SLC2A4,ADD1,HTT,MICB,AMFR,MADD,MPP2,PLCB2,RABGGTA |
| 4.723e-02 | -3.05 | PID_ERBB2_ERBB3_PATHWAY | MSigDB lists | PID_ERBB2_ERBB3_PATHWAY | 44 | 11 | 17758 | 2588 |
NF2,AKT1,PIK3R1,PIK3CA,ERBB2,NRG2,NRG1,ERBB3,PIK3CD,FOS,PRKACA |
| 4.723e-02 | -3.05 | V$HOX13_01 | MSigDB lists | V$HOX13_01 | 44 | 11 | 17758 | 2588 |
CCND1,TRIM8,CDK16,CALD1,LMO4,YES1,UNC5B,NDFIP1,GPR161,FOXA1,NEO1 |
| 4.723e-02 | -3.05 | BIOCARTA_TCR_PATHWAY | MSigDB lists | BIOCARTA_TCR_PATHWAY | 44 | 11 | 17758 | 2588 |
CALM2,PLCG1,FYN,CALM1,NFKBIA,PIK3R1,PIK3CA,CALM3,ELK1,FOS,RASA1 |
| 4.725e-02 | -3.05 | negative regulation of stem cell differentiation | biological process | GO:2000737 | 43 | 11 | 16441 | 2455 |
HES1,NCOA3,BMP7,VASN,PRICKLE1,DAB2IP,EFNA1,WNT3A,TRIM62,SIX4,FOXA1 |
| 4.725e-02 | -3.05 | CDKN1A (cyclin-dependent kinase inhibitor 1A (p21, Cip1)) | protein interactions | 1026 | 284 | 56 | 16036 | 2547 |
CCNE2,CASP3,SPRED1,TXN,CTSB,HDAC11,TP53,CCNO,CUL1,HERC5,COL4A5,CCNB1,HDAC6,SBF1,EXT2,GNB2,SDF4,CDK14,TP73,CCND1,RB1,CPNE2,NOV,PCNA,CCNA2,GNB5,MITF,MSH2,CKS1B,CDKN1B,NTN4,PIM1,LRIF1,HSPA2,PHKG2,CKS2,AKT1,TNIP1,SNTB2,CDC20,PKM,TXNDC11,CDK1,PDHX,ABR,VCP,OPTN,CRTC2,E2F1,PIAS2,TLE1,HDAC1,MAP3K5,CCNB2,TBC1D4,NRBP1 |
| 4.727e-02 | -3.05 | SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | REACTOME pathways | R-HSA-399955 | 14 | 5 | 8202 | 1235 |
FYN,PLXNA1,SEMA3A,RND1,FARP2 |
| 4.733e-02 | -3.05 | axis elongation | biological process | GO:0003401 | 28 | 8 | 16441 | 2455 |
AREG,TMTC3,FGFR2,PTK7,SOX9,TFAP2C,WNT3A,SPRY2 |
| 4.733e-02 | -3.05 | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902175 | 28 | 8 | 16441 | 2455 |
SIRT1,SOD1,PINK1,AKT1,P4HB,SOD2,MAPK7,HSPB1 |
| 4.733e-02 | -3.05 | response to epidermal growth factor | biological process | GO:0070849 | 28 | 8 | 16441 | 2455 |
IL1R1,PLCG1,BAG4,AKT1,IQGAP1,SOX9,DAB2IP,EGFR |
| 4.733e-02 | -3.05 | heart valve morphogenesis | biological process | GO:0003179 | 28 | 8 | 16441 | 2455 |
BMP2,ACVR1,CYR61,SOX9,GATA3,TWIST1,NOTCH2,EFNA1 |
| 4.733e-02 | -3.05 | cellular response to vascular endothelial growth factor stimulus | biological process | GO:0035924 | 28 | 8 | 16441 | 2455 |
MAPKAPK2,AKT1,NR4A1,DAB2IP,EGR3,HSPB1,FLT3,NRP2 |
| 4.733e-02 | -3.05 | chromosome condensation | biological process | GO:0030261 | 28 | 8 | 16441 | 2455 |
TOP2A,PAPD7,CDCA5,NUSAP1,GPER1,CCNB1,NCAPG2,SMC4 |
| 4.734e-02 | -3.05 | intrinsic apoptotic signaling pathway | biological process | GO:0097193 | 177 | 35 | 16441 | 2455 |
ZMAT1,CASP3,BMF,TRAF2,XIAP,TP53,CUL1,BCL2L1,ZNF385B,IER3,TP73,PDCD10,SIVA1,MSH2,BAX,TMBIM6,DAB2IP,SELK,SCN2A,MSH6,CYP1B1,SIRT1,PRODH,AKT1,CASP9,ERO1A,PIK3R1,CASP4,SGPP1,DNAJC10,CASP7,ITPR1,E2F1,MAP3K5,MELK |
| 4.735e-02 | -3.05 | regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001242 | 148 | 30 | 16441 | 2455 |
PPIF,SIRT1,SOD1,PINK1,NKX3-1,BMF,AKT1,FIGNL1,PLAUR,SOD2,TP53,BCL2L1,SEPT4,PRKRA,ERP29,BCAP31,MAPK8IP1,G2E3,TP73,DAPK2,DNM1L,P4HB,WFS1,BAX,PLEKHF1,TMBIM6,BUB1,MAPK7,CDKN2D,HSPB1 |
| 4.735e-02 | -3.05 | EF-hand_1 | pfam domains | PF00036 | 14 | 5 | 16629 | 2504 |
CALM3,S100A11,HPCAL4,CABP1,NCS1 |
| 4.735e-02 | -3.05 | PhoLip_ATPase_C | pfam domains | PF16212 | 14 | 5 | 16629 | 2504 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 4.735e-02 | -3.05 | Cyt-b5 | pfam domains | PF00173 | 14 | 5 | 16629 | 2504 |
NENF,FADS2,FA2H,CYB5A,PGRMC1 |
| 4.735e-02 | -3.05 | PhoLip_ATPase_N | pfam domains | PF16209 | 14 | 5 | 16629 | 2504 |
ATP8B1,ATP8B3,ATP9A,ATP10D,ATP8A1 |
| 4.735e-02 | -3.05 | BEX | pfam domains | PF04538 | 14 | 5 | 16629 | 2504 |
TCEAL8,NGFRAP1,BEX2,WBP5,TCEAL4 |
| 4.744e-02 | -3.05 | Mito_carr | pfam domains | PF00153 | 53 | 13 | 16629 | 2504 |
SLC25A48,SLC25A45,SLC25A24,SLC25A4,SLC25A13,SLC25A40,SLC25A27,SLC25A38,SLC25A5,SLC25A30,SLC25A43,SLC25A35,SLC25A36 |
| 4.746e-02 | -3.05 | Ephrin B reverse signaling | Pathway Interaction DB | ephrinbrevpathway | 27 | 10 | 2227 | 480 |
FYN,RGS3,PIK3R1,PIK3CA,YES1,EPHB4,MAP3K7,TIAM1,EFNB1,ITGA2B |
| 4.748e-02 | -3.05 | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP | MSigDB lists | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP | 19 | 6 | 17758 | 2588 |
ATRNL1,CYP26B1,FHL1,AREG,MYBL1,METTL7A |
| 4.748e-02 | -3.05 | PHOSPHOINOSITIDE_BINDING | MSigDB lists | PHOSPHOINOSITIDE_BINDING | 19 | 6 | 17758 | 2588 |
ZFYVE16,ARAP2,WDFY1,ARAP3,CCDC88A,ARAP1 |
| 4.748e-02 | -3.05 | NIELSEN_LIPOSARCOMA_DN | MSigDB lists | NIELSEN_LIPOSARCOMA_DN | 19 | 6 | 17758 | 2588 |
MFSD3,CYFIP2,UBE2T,ETV4,CSRP2,NRP2 |
| 4.748e-02 | -3.05 | REGULATION_OF_PROTEIN_STABILITY | MSigDB lists | REGULATION_OF_PROTEIN_STABILITY | 19 | 6 | 17758 | 2588 |
AURKA,CDKN2AIP,ISOC2,PTEN,PEX6,FBXO7 |
| 4.748e-02 | -3.05 | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | MSigDB lists | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | 19 | 6 | 17758 | 2588 |
F11R,PIM1,UNC5B,PVRL2,PDGFB,LEPR |
| 4.748e-02 | -3.05 | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP | MSigDB lists | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP | 19 | 6 | 17758 | 2588 |
AK4,PKD2,FRMD6,SNTB2,NAB2,SOCS3 |
| 4.748e-02 | -3.05 | GRANDVAUX_IRF3_TARGETS_DN | MSigDB lists | GRANDVAUX_IRF3_TARGETS_DN | 19 | 6 | 17758 | 2588 |
SORL1,TIMP3,GEM,STK17B,RASA1,PPP2R3A |
| 4.748e-02 | -3.05 | TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_UP | MSigDB lists | TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_UP | 19 | 6 | 17758 | 2588 |
LAMP2,B3GALNT1,CDH1,GLCCI1,RAB11FIP1,CKS2 |
| 4.748e-02 | -3.05 | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN | MSigDB lists | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN | 19 | 6 | 17758 | 2588 |
TNS3,CTGF,EPAS1,CALD1,L1CAM,FHL2 |
| 4.748e-02 | -3.05 | CARBOHYDRATE_TRANSPORT | MSigDB lists | CARBOHYDRATE_TRANSPORT | 19 | 6 | 17758 | 2588 |
SLC2A4,SORBS1,SLC2A8,SLC35A1,SLC35B4,EDNRA |
| 4.748e-02 | -3.05 | MICROTUBULE_ORGANIZING_CENTER_PART | MSigDB lists | MICROTUBULE_ORGANIZING_CENTER_PART | 19 | 6 | 17758 | 2588 |
TUBG1,TOP2A,CNTROB,UXT,TUBGCP6,CKAP5 |
| 4.748e-02 | -3.05 | RHO_GTPASE_ACTIVATOR_ACTIVITY | MSigDB lists | RHO_GTPASE_ACTIVATOR_ACTIVITY | 19 | 6 | 17758 | 2588 |
ARHGEF10L,DOCK4,ARAP3,ARHGAP4,RALBP1,ARAP1 |
| 4.748e-02 | -3.05 | BIOCARTA_STATHMIN_PATHWAY | MSigDB lists | BIOCARTA_STATHMIN_PATHWAY | 19 | 6 | 17758 | 2588 |
MAPK13,PRKAR2B,CCNB1,CDK1,CAMK2G,PRKAR1A |
| 4.762e-02 | -3.04 | T cell receptor signaling pathway | KEGG pathways | ko04660 | 104 | 23 | 6908 | 1076 |
RHOA,AKT1,NFKBIE,PIK3R1,PRKCQ,TEC,CBL,FOS,BCL10,PAK6,CD8A,PLCG1,FYN,NFKBIA,PAK2,PIK3CA,DLG1,MAPK13,MAPK11,PIK3CD,MAP3K7,RASGRP1,MAPK12 |
| 4.762e-02 | -3.04 | T cell receptor signaling pathway | KEGG pathways | hsa04660 | 104 | 23 | 6908 | 1076 |
RHOA,AKT1,NFKBIE,PIK3R1,PRKCQ,TEC,CBL,FOS,BCL10,PAK6,CD8A,PLCG1,FYN,NFKBIA,PAK2,PIK3CA,DLG1,MAPK13,MAPK11,PIK3CD,MAP3K7,RASGRP1,MAPK12 |
| 4.768e-02 | -3.04 | rhabdomyosarcoma | COSMIC cancer mutations | rhabdomyosarcoma | 4310 | 661 | 17775 | 2585 |
DOC2A,HECA,ACACB,ADD1,IBTK,GRIK2,TRIM5,DNAJC3,HEXB,RET,FBXO2,NRG2,BAIAP3,KIF26A,PHF1,LTBP3,EPDR1,CDKN2C,TP73,NPM2,ZYX,TGFBR3,DNAH6,CABP1,PAQR5,RDH14,ALDH1A3,KLF3,CRY2,IL10RB,ODF2L,APOBEC3G,ERAP2,DNAAF3,NEK4,NWD1,SPEF2,SMARCA2,TNIP1,CDA,LOXL2,MYOM1,PNKD,COL12A1,LCP1,PIAS3,ENPP1,GRID2IP,DNM1L,ANKRD6,MYLK,FAM114A1,NOD2,PDPR,ZNF720,SCN5A,CYP2J2,ITGA6,RAB23,ZNRF3,CCDC64B,MERTK,LMNA,MARCH8,FAM189A1,CD22,MEGF8,FLRT3,ZIC5,FBXO7,CADPS2,USP1,ALPK1,CNGA1,ZMYM1,MOXD1,PPP6R1,SLC37A1,MYBL2,KIF20B,GNA11,IL1R1,NCOA3,ETS2,HTT,SEMA4D,ITPR1,OSMR,DYSF,DRP2,TMEM173,XDH,ADAMTS16,DOCK9,MTM1,PAPSS2,LFNG,GALNT12,FAM131C,PTTG1,WDTC1,RGS20,PKP2,TESK2,KIAA1147,UHRF1BP1L,MUC16,SH3BP1,RTKN2,MYT1,SCN3A,TMCC2,MX1,CAMSAP3,COL6A2,ERMP1,RIPK2,SYNE2,GIGYF1,NFIX,CCNB3,WFS1,CORO1C,SLC9A6,PLEKHG1,FAM149A,DMWD,CTHRC1,PARP14,ESRP1,RASSF7,NUCB2,PLPPR4,GSTP1,ETS1,BEX2,ICAM1,NEO1,CXCL16,ANK1,ADD3,IRAK1,ARSG,GPC3,TUBGCP6,FDXR,TMBIM6,IGFBP2,NPTXR,RAG1,TPCN1,PARP9,AMOTL2,FMN1,MFSD2B,PIK3R1,PLEKHA7,MYEOV,PGBD1,EMP3,PROM1,PLOD2,ATXN7L3,RAB11FIP2,ACVRL1,FAM3C,DBI,PPM1H,FBXO44,CENPE,FHL1,FOXA1,PHC1,TMEM131,BCAM,KIAA1462,AGRN,FHDC1,NENF,GALM,SPTB,TFAP2E,SUSD2,ENTPD4,NUP210,TM9SF2,CTNNB1,P4HB,PSMC2,TMEM143,ABCA2,ANO4,TLN2,NEB,CCDC38,ZNF462,THRB,MCTP1,MARK1,PTPN18,CD55,EZR,CR2,IDH1,OPTN,KDM4D,TNS4,HS6ST1,PLCH1,MAP2,P4HA2,ZNF367,RAB11FIP1,ARRDC1,KLF11,PIK3C2B,PIEZO1,TTC39C,EPB41L4A,TC2N,PRSS8,USH1C,LGALS3,RASA2,PDCL,HES2,CNTNAP2,DOCK11,FBLN1,RSAD1,ANO1,SSX2IP,RB1,KIAA0895,UBE2Q2,IGF1R,FRAS1,TBCD,SLC30A6,PLCB2,DPYSL5,USP31,SPATA13,TCF7,RASGRP2,FA2H,H1F0,COL13A1,ITGA7,NLRC5,LTBP2,PLD1,ZDBF2,CTBP1,RAD21,USP43,UPF3B,TP53,ERBB2,P2RX7,SLC7A2,C1orf116,CYP26A1,SYTL2,IER3,PDGFA,SRPX,WDR44,TACC2,PLCG2,BCL6,GYS1,ESPN,NOTCH3,OAS3,MINPP1,SCN2A,PPIF,AKT1,ACO1,PTGER4,ATP13A2,MYPOP,DUOX1,ZNF628,PTPRJ,ABHD12,PTK7,STK38,ADAMTS14,MAOA,IRF7,ANXA9,ST3GAL1,ZC3HC1,COL9A3,DYRK3,TM2D2,CDH22,TRAPPC10,KLHL13,MACC1,RUSC2,CTSB,GDF15,JAG2,CRABP2,DSE,LBR,SH2D4A,FZD6,CD109,TFAP2A,FAM63A,TSPAN13,BUB1,CAMK2G,GCNT1,LRRC24,IGDCC4,NFE2L3,P2RX4,HMMR,MOSPD2,PLAUR,LITAF,PPARA,PRICKLE1,DPP9,MAML2,COL7A1,CAPNS1,NPDC1,RNPEP,BBS2,TXNDC11,BCAR1,CNOT2,SERPINA1,FAT4,TWSG1,NAT1,NETO2,E2F1,PPP2R3C,ICOSLG,TBC1D4,PTGES,ARHGEF4,GOLGB1,GAA,HSPG2,SSH1,TAP1,VASH1,FAM101B,PICK1,CYP1A1,OSBPL3,RGS3,PIK3CA,KCNS3,POLL,AOX1,ATRNL1,HYLS1,MTMR11,RCAN3,SPATA18,ACVR1C,CASP9,KIF13A,CCNF,ULK2,PLK2,GNPTAB,MAPK13,TANC2,LZTS1,FGD1,DDX58,INPPL1,FRMD4A,DHPS,TBC1D1,DGKQ,KIF23,NOTCH2,SLC1A3,PDXDC1,KIAA1161,DOPEY2,CYR61,ZNRF2,NECAB3,AIM1,MSH2,OPN3,SORL1,PIKFYVE,CTSD,EEF1D,RIMS2,SOCS5,IGSF3,DNAI1,GFPT1,SPATA20,KCNJ12,PRSS23,MFI2,ADCK3,MICB,AMER1,DCHS1,WHSC1,PYGL,ATP8B3,ANTXR1,FRMD4B,FAS,DGKH,AP1AR,TJP3,FAM64A,DCK,AGBL5,FAM83D,CABIN1,PER3,PLIN3,MAP3K5,IFIH1,PKD1L2,EHD1,PLA2G4A,PLEKHG3,SPRED1,CAPN12,NLRX1,DDIT4L,IRX4,KCTD12,FLT3,CYP39A1,EPM2A,APLP2,FAM46A,FICD,PHKA2,LGMN,NR2C1,NAGA,TBC1D10B,ATG4D,DOCK4,SEC23A,FOXJ2,TEP1,PRKCQ,PYGO1,ITPR3,ALCAM,ATP10D,ZNF469,NIN,EPHA10,ACAD10,HAGHL,KIAA1804,TRIOBP,FAM195A,SLC27A1,NRG1,KLF5,MLKL,COBL,ANKRD13D,PCOLCE,CENPI,PBX3,CYB561,APOBEC3H,PLD2,DNAH3,MGAT1,PTEN,FJX1,ERBB3,MAP3K7,GFI1,MSH6,TGIF1,SHMT1,ARAP2,PAPD7,TCFL5,FURIN,DIAPH2,LRRC1,GRTP1,RGS9,MAMDC4,FGFR2,RIN3,ABCB1,ERAP1,RABL6,FZD5,NCAPG2,OCLN,DEF6,USP16,JARID2,RGMA,LTBP1,NMRK1,TMEM184B,CPT2,CAMKK1,EPHX4,DNER,TMC1,PTCHD4,SH3KBP1,ARHGEF10L,SIPA1L2,LRRC6,ARHGEF37,TSPAN6,ANKFN1,PHTF1,CAPG,DLG1,MYH14,SLC39A10,TECR,IL1RAP,CYP1B1,LAP3,RNF165,RGAG1,TCN2,NEIL1,HPSE,MADD,RBM43,APBA2,RAP1GAP,CAPN1,GRN,FAM213B,ARAP3,PEX6,PYROXD2,ASL,ABCG2,PHLPP1,ADAMTSL4,TYW3,FAM20C,KCNN4,COL6A1,EBF4,FNIP1,SRP54,FXYD5,NPTN,ZRANB1,CCDC88A,SNED1,PODXL2,PARD3B,GYLTL1B,BTN3A2,VWA1,KIAA1109,RANBP9,EGFR,MUM1L1,GNAS,FECH,TSC1,RHOBTB2,YOD1,DONSON,SHROOM2,FBXW5,CCNE2,NCKAP5,ZSWIM5,SORBS1,MORC4,COL18A1,ARHGEF16,SS18,ZNF687,ARTN,SMO,STEAP3,ECE1,NFKB2,ETHE1,LOXL1,SLC39A8,OSTM1,DUSP4,DOCK5,ARHGAP35,ALDH5A1,BFSP1,SPTBN5,PLXND1,AKNA,REEP4,ABCA1,CBX4,GLIS3,ARHGEF11,LRP4,COL4A5,NOTUM,SBF1,ITGA2B,TMEM63A,HDAC9,KIF5B,IL17RB,IRF2BPL,SNX13,CARD8,ADORA1,MLPH,LLGL2,TOX2,KIAA0319,BRD7,IQGAP3,C12orf75,RPGR,MYO5A,SUN2,DCAF6,WNT10B,ASPM,PHLDB3,NR4A1,SYBU,LRRC66,TTC7A,POLD3,LEPR,MPV17L2,SPAG1,HLA-B,CASP7,SOX8,PLOD3,AHR,NGEF,ZNF596 |
| 4.769e-02 | -3.04 | PHOSPHORIC_MONOESTER_HYDROLASE_ACTIVITY | MSigDB lists | PHOSPHORIC_MONOESTER_HYDROLASE_ACTIVITY | 105 | 22 | 17758 | 2588 |
PTPN18,DLGAP5,PTPRU,INPP5D,PTPN9,PTPRH,DUSP4,SBF1,DUSP5,EPM2A,PTPRF,INPP5E,NT5C2,PTPRJ,PTEN,OCRL,DLG1,INPP4B,PPP1CA,MINPP1,PTPRE,DUSP1 |
| 4.769e-02 | -3.04 | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP | MSigDB lists | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP | 105 | 22 | 17758 | 2588 |
ADD1,BLVRB,BNIP3L,KCTD20,MORF4L2,PRRC1,BAIAP3,DNAJB14,CDS1,SYDE2,KIF5B,ENPP1,AP1AR,NCOA3,FNIP1,DIXDC1,KLF9,CTTN,F2R,HSPB1,ARNT,SYTL3 |
| 4.769e-02 | -3.04 | HALLMARK_PI3K_AKT_MTOR_SIGNALING | MSigDB lists | HALLMARK_PI3K_AKT_MTOR_SIGNALING | 105 | 22 | 17758 | 2588 |
PRKAA2,HSP90B1,AKT1,RPS6KA1,TRAF2,ITPR2,CDK1,EGFR,CALR,PITX2,PLCG1,ADRBK1,PTEN,RALB,E2F1,CDKN1B,CAB39,PPP1CA,MAP3K7,PIKFYVE,TIAM1,RPS6KA3 |
| 4.775e-02 | -3.04 | Transport and synthesis of PAPS | REACTOME pathways | R-HSA-174362 | 6 | 3 | 8202 | 1235 |
PAPSS2,SLC35B3,PAPSS1 |
| 4.775e-02 | -3.04 | RSK activation | REACTOME pathways | R-HSA-444257 | 6 | 3 | 8202 | 1235 |
RPS6KA2,RPS6KA1,RPS6KA3 |
| 4.775e-02 | -3.04 | Reactions specific to the complex N-glycan synthesis pathway | REACTOME pathways | R-HSA-975578 | 6 | 3 | 8202 | 1235 |
MAN2A2,FUCA1,FUT8 |
| 4.775e-02 | -3.04 | Cam-PDE 1 activation | REACTOME pathways | R-HSA-111957 | 6 | 3 | 8202 | 1235 |
CALM2,CALM3,CALM1 |
| 4.775e-02 | -3.04 | IRF3 mediated activation of type 1 IFN | REACTOME pathways | R-HSA-1606341 | 6 | 3 | 8202 | 1235 |
NLRP4,TMEM173,DTX4 |
| 4.779e-02 | -3.04 | DIL | pfam domains | PF01843 | 6 | 3 | 16629 | 2504 |
MYO5B,MYO5A,MYO5C |
| 4.779e-02 | -3.04 | RYDR_ITPR | pfam domains | PF01365 | 6 | 3 | 16629 | 2504 |
ITPR2,ITPR3,ITPR1 |
| 4.779e-02 | -3.04 | Ins145_P3_rec | pfam domains | PF08709 | 6 | 3 | 16629 | 2504 |
ITPR2,ITPR3,ITPR1 |
| 4.779e-02 | -3.04 | BTG | pfam domains | PF07742 | 6 | 3 | 16629 | 2504 |
BTG3,BTG1,TOB1 |
| 4.779e-02 | -3.04 | GoLoco | pfam domains | PF02188 | 6 | 3 | 16629 | 2504 |
GPSM2,RGS12,RAP1GAP |
| 4.779e-02 | -3.04 | RBD | pfam domains | PF02196 | 6 | 3 | 16629 | 2504 |
RGS12,RGS14,TIAM1 |
| 4.779e-02 | -3.04 | zf-MIZ | pfam domains | PF02891 | 6 | 3 | 16629 | 2504 |
PIAS3,ZMIZ1,PIAS2 |
| 4.779e-02 | -3.04 | CLTH | pfam domains | PF10607 | 6 | 3 | 16629 | 2504 |
GID8,RMND5A,RANBP9 |
| 4.779e-02 | -3.04 | GED | pfam domains | PF02212 | 6 | 3 | 16629 | 2504 |
MX1,DNM1L,DNM2 |
| 4.779e-02 | -3.04 | Notch | pfam domains | PF00066 | 6 | 3 | 16629 | 2504 |
NOTCH2,NOTCH3,GNPTAB |
| 4.779e-02 | -3.04 | Dynamin_M | pfam domains | PF01031 | 6 | 3 | 16629 | 2504 |
MX1,DNM1L,DNM2 |
| 4.779e-02 | -3.04 | RIH_assoc | pfam domains | PF08454 | 6 | 3 | 16629 | 2504 |
ITPR2,ITPR3,ITPR1 |
| 4.779e-02 | -3.04 | Na_trans_cytopl | pfam domains | PF11933 | 6 | 3 | 16629 | 2504 |
SCN5A,SCN2A,SCN3A |
| 4.780e-02 | -3.04 | positive regulation of lipase activity | biological process | GO:0060193 | 97 | 21 | 16441 | 2455 |
RHOA,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,ARF4,EGFR,PLIN5,TXK,EDNRA,CALM2,PLCG1,ADRBK1,CYR61,FGFR2,ARL1,ITPR1,PLCB2,PRKAR1A |
| 4.789e-02 | -3.04 | POSITIVE_REGULATION_OF_CELLULAR_PROCESS | MSigDB lists | POSITIVE_REGULATION_OF_CELLULAR_PROCESS | 662 | 112 | 17758 | 2588 |
CASP3,ACVR1,NF2,EPAS1,IL15,GRIK2,TP53,ERBB2,CUL1,IL18,AIFM2,SLC20A1,BARD1,FLT3,ARHGEF10L,CCND1,TP73,DAPK2,PDGFA,NPM2,CDKN2C,CDH1,STIM1,TSPAN6,SIVA1,IL31RA,BCL6,CDKN1B,ARNT2,TFG,F2R,MAP3K3,MX1,CDKN2AIP,CXXC5,RIPK2,BNIP3L,HTATIP2,NUSAP1,CD40,CBL,STK17B,CASP4,PGF,PLK2,SECTM1,PPP2R4,NOD2,CANT1,ARF6,TRAF5,AIFM3,ABCA1,CAPN1,GLIS3,TAOK2,CDKN1C,DHPS,ARHGEF11,DAP,BIK,SORBS3,TGFBR1,NOTCH2,ETS1,ADAMTSL4,TOP2A,ADORA1,IGF1R,TIMP1,PTEN,GATA2,BMP7,BAX,DAPK1,ZDHHC13,SLC44A2,CD70,MDFIC,ERCC2,NPTN,CITED2,EEF1D,SOCS5,RHOA,RGMB,LITAF,PPARA,CAPNS1,RUNX3,ELK1,BCAR1,EGFR,CDK5R1,FAS,BCL10,STK17A,TSC1,BTG1,LDLRAP1,ACVRL1,SCG2,HTT,CSF1,FGF18,ARAP1,HMGA1,MAP3K5,ICOSLG,NDFIP1,UBE2C,CD81 |
| 4.793e-02 | -3.04 | FG-GAP | interpro domains | IPR013517 | 19 | 6 | 18293 | 2672 |
ITGAV,ITGA3,ITGA7,ITGA6,ITGA2B,GPLD1 |
| 4.793e-02 | -3.04 | Int_alpha_beta-p | interpro domains | IPR013519 | 19 | 6 | 18293 | 2672 |
ITGAV,ITGA3,ITGA7,ITGA6,ITGA2B,GPLD1 |
| 4.797e-02 | -3.04 | Dorso-ventral axis formation | KEGG pathways | ko04320 | 27 | 8 | 6908 | 1076 |
CPEB4,ETS2,NOTCH2,NOTCH3,ETS1,ETV7,CPEB2,EGFR |
| 4.797e-02 | -3.04 | Dorso-ventral axis formation | KEGG pathways | hsa04320 | 27 | 8 | 6908 | 1076 |
CPEB4,ETS2,NOTCH2,NOTCH3,ETS1,ETV7,CPEB2,EGFR |
| 4.797e-02 | -3.04 | neuromuscular junction development | biological process | GO:0007528 | 38 | 10 | 16441 | 2455 |
SNTA1,AGRN,FGFR2,ETV5,LRP4,CACNA2D2,ERBB2,COL4A5,CACNB4,F2R |
| 4.805e-02 | -3.04 | fatty acid metabolic process | biological process | GO:0006631 | 290 | 54 | 16441 | 2455 |
PLA2G4A,PRKAA2,ACACB,FAM213B,CPT2,CYP2J2,SCD5,ELOVL7,PRKAA1,MGST2,LPIN3,ECI1,PER2,SGPL1,CYP1A1,SLC27A6,CYP2S1,ECI2,ABCD1,ACSL4,ACOX2,TECR,ACAD8,SYK,MYO5A,ABCC1,GPX4,CYP1B1,FADS2,PCCB,ELOVL3,PPARA,PRKAR2B,RNPEP,POR,CYP4F3,MAPKAPK2,PTGS2,ALDH5A1,PRKAG2,FA2H,ACADSB,FAAH,ACAD10,PEX2,PLA2G15,SLC27A1,ADIPOR1,CYP2U1,ACADM,LTA4H,SLC27A3,PTGES,ACOT7 |
| 4.809e-02 | -3.03 | regulation of T cell activation | biological process | GO:0050863 | 278 | 52 | 16441 | 2455 |
CASP3,LGALS3,DHPS,IL15,HLA-E,TRAF2,GATA3,ERBB2,IL18,EGR3,CD274,TNFSF9,EFNB1,HLA-A,CD46,RAC2,CTNNB1,IL6ST,PAK2,BCL6,PIK3CA,DLG1,IGFBP2,C10orf54,MAP3K7,RAG1,FLOT2,SYK,RASGRP1,SOCS5,HES1,SOD1,CD55,RHOA,RIPK2,AKT1,LGALS8,ITCH,PIK3R1,PDE5A,PRKCQ,YES1,SOX13,BCL10,CD83,FYN,NOD2,ICOSLG,NDFIP1,JAK3,PRKAR1A,IRF1 |
| 4.810e-02 | -3.03 | cellular carbohydrate catabolic process | biological process | GO:0044275 | 33 | 9 | 16441 | 2455 |
CALM2,PGM1,GAA,CALM1,MGAM,PYGL,CALM3,PHKA2,PHKG2 |
| 4.810e-02 | -3.03 | regulation of natural killer cell mediated immunity | biological process | GO:0002715 | 33 | 9 | 16441 | 2455 |
LAMP1,HLA-B,PVRL2,HLA-E,SERPINB9,TAP1,HLA-A,RASGRP1,SMAGP |
| 4.810e-02 | -3.03 | regulation of glycolytic process | biological process | GO:0006110 | 33 | 9 | 16441 | 2455 |
PRKAA2,INSR,PRKAG2,PRKAA1,PPARA,TP53,P2RX7,ARNT,IER3 |
| 4.810e-02 | -3.03 | response to mineralocorticoid | biological process | GO:0051385 | 33 | 9 | 16441 | 2455 |
CALM2,CCND1,CTGF,CALM1,FOSB,BAX,CALM3,GPER1,FOS |
| 4.810e-02 | -3.03 | positive regulation of cytokine-mediated signaling pathway | biological process | GO:0001961 | 33 | 9 | 16441 | 2455 |
RIPK2,AGPAT2,TRAF2,CSF1,AXL,NLRC5,IRF7,GFI1,TXK |
| 4.810e-02 | -3.03 | SET (SET nuclear proto-oncogene) | protein interactions | 6418 | 102 | 23 | 16036 | 2547 |
OTUD5,UGP2,NR3C1,CALM1,TP53,RGS20,FTH1,IGSF8,CCNB1,FOS,DGKE,CDK5R1,ICAM1,NUCB1,SWAP70,CDH1,PLOD2,PPP2R4,KLF5,SGOL1,CD81,PRKAR1A,IRF1 |
| 4.810e-02 | -3.03 | CALU (calumenin) | protein interactions | 813 | 102 | 23 | 16036 | 2547 |
GAA,FAF2,HSP90B1,CTNNAL1,HDAC11,FBXO6,NUCB2,DPP8,ILK,PRKACA,EGFR,VCP,CALR,PCNA,IRAK1,P4HB,IARS2,SH3GLB2,PRKCDBP,AURKA,PTBP3,PLIN3,ARPC2 |
| 4.812e-02 | -3.03 | single organism reproductive process | biological process | GO:0044702 | 1037 | 174 | 16441 | 2455 |
CCNI,ACVR1,LGR4,EPAS1,AK7,GNPDA1,HEXB,GATA3,UBE2Q1,PLAC1,CCNB1,SEPT4,PDGFB,SDC1,PICK1,NPM2,CYP1A1,HSF2,RPS6KA2,LRRC6,CTNNB1,PAQR5,DNM2,AKR1B1,TIPARP,SMARCA2,SPEF2,SOD1,CELSR2,CDYL,TFAP2C,CCNF,IDH1,CDK1,HS6ST1,AREG,HOXA9,TDRD7,GAB1,E2F8,NR2C2,PCSK5,GRN,CDKN1C,SERPINE2,SOX9,ETV5,MTL5,RACGAP1,FBLN1,MERTK,LMNA,B4GALNT1,CALR,SPP1,DAZAP1,ITGA3,IGF1R,CYR61,GATA2,SPIN4,MSH2,TMED2,MDFI,PAQR7,CYP26B1,SPATA20,REC8,TESK1,SPA17,ATP8B3,KDM3A,EGFR,IL1R1,NCOA3,INSR,HTT,PVRL2,PLPP3,UTP14C,SFMBT1,HOOK1,RARG,APOL2,EGLN1,GRHL2,LFNG,ST14,CAST,PTTG1,TESK2,ERBB2,TDRKH,BCL2L1,PRKACA,EMP2,BCAP31,MNS1,CCND1,CD46,BCL6,PLK4,ACSL4,HSPA2,GPX4,SIRT1,AKT1,FZD4,IGSF8,PYGO1,CDC25C,SOCS3,PTGS2,SPIN3,PAFAH1B3,AXL,OVOL1,ARNT,COL9A3,NKX3-1,CTSB,CIT,CENPI,BIK,TGFBR1,GMCL1,JAG2,SBF1,ETS1,SIX4,ICAM1,SGPL1,E2F7,ITGB8,CDK16,PTEN,CST3,TOX2,BAX,CD9,UBE2J1,TMBIM6,TTPA,CRTAP,HES1,ADAMTS2,TCFL5,ASPM,EIF5A2,UBE2A,DIAPH2,AKAP3,FNDC3A,BBS2,NDRG3,SPAG1,PRDX4,PITX2,BTG1,PRDX3,FGFR2,CTSV,SPINT2,E2F1,ARRB1,SERPINB5,PKD2,HOXB13,FZD5,OSR1,SOX8,ZMIZ1,AHR,FOXA1 |
| 4.812e-02 | -3.03 | MORI_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_MATURE_B_LYMPHOCYTE_UP | 88 | 19 | 17758 | 2588 |
POU6F1,ARHGEF3,ADD1,SELL,CR2,CD40,ETS1,CMTM6,LCP1,SGPP1,CD83,B4GALNT1,AIM1,SORL1,FAM102A,CNOT6L,RGS14,IL10RB,ABCA1 |
| 4.815e-02 | -3.03 | regulation of chromosome segregation | biological process | GO:0051983 | 75 | 17 | 16441 | 2455 |
PLK1,DLGAP5,CIT,PTTG1,CDC20,RACGAP1,KIF2C,AURKB,CCNB1,RB1,CTNNB1,PTEN,CDCA5,NEK2,BUB1,UBE2C,ESPL1 |
| 4.818e-02 | -3.03 | positive regulation of cell morphogenesis involved in differentiation | biological process | GO:0010770 | 154 | 31 | 16441 | 2455 |
EPB41L5,RHOA,DMTN,ARHGEF7,EPHA4,RGCC,CRABP2,ILK,MAP1B,BMP2,CALR,CTNNB1,CDKL5,SEMA4D,BHLHB9,MEGF8,LIMK1,WWTR1,DNM2,TRIOBP,EFNA5,NRG1,TNFRSF12A,TWIST1,ARPC2,ITPKA,WNT3A,NTN1,TIAM1,SHOX2,L1CAM |
| 4.826e-02 | -3.03 | skin-carcinoma | COSMIC cancer mutations | skin-carcinoma | 39 | 10 | 17775 | 2585 |
GNAS,CALR,CTNNB1,IGF1R,AKT1,KIAA1804,TP53,ERBB2,ERBB3,EGFR |
| 4.827e-02 | -3.03 | SUPT7L (SPT7-like STAGA complex gamma subunit) | protein interactions | 9913 | 22 | 7 | 16036 | 2547 |
SIRT1,PLAC1,SERTAD2,CDCA4,ATXN7L3,TADA2B,TP53 |
| 4.827e-02 | -3.03 | FKBP9 (FK506 binding protein 9) | protein interactions | 11328 | 22 | 7 | 16036 | 2547 |
EZR,STK39,PDCD10,H2AFV,NUBP1,RAD23A,EHD1 |
| 4.827e-02 | -3.03 | NFE2 (nuclear factor, erythroid 2) | protein interactions | 4778 | 22 | 7 | 16036 | 2547 |
NFE2L3,WWP1,PHYHIP,TXN,MAFF,ITCH,ELF5 |
| 4.827e-02 | -3.03 | TRNT1 (tRNA nucleotidyl transferase, CCA-adding, 1) | protein interactions | 51095 | 22 | 7 | 16036 | 2547 |
EZR,PYGL,CTSA,SH3BP1,H2AFV,GNPDA1,RAD23A |
| 4.827e-02 | -3.03 | DAB2IP (DAB2 interacting protein) | protein interactions | 153090 | 22 | 7 | 16036 | 2547 |
TP73,CUL1,MAP3K5,AKT1,TRAF2,PIK3R1,TP53 |
| 4.827e-02 | -3.03 | EPHX1 (epoxide hydrolase 1, microsomal (xenobiotic)) | protein interactions | 2052 | 22 | 7 | 16036 | 2547 |
DNAJB11,CDKN2AIP,FAM189A2,TMEM30A,TSPAN17,TMX1,SPINT2 |
| 4.827e-02 | -3.03 | DCP1B (decapping mRNA 1B) | protein interactions | 196513 | 22 | 7 | 16036 | 2547 |
GRN,KANK2,E2F7,BAG4,PIM1,ZFP36,DCP2 |
| 4.827e-02 | -3.03 | SCYL2 (SCY1-like, kinase-like 2) | protein interactions | 55681 | 22 | 7 | 16036 | 2547 |
ARRB1,GTF3A,SOD1,FBXO6,CTSD,RAPGEF2,ZFYVE9 |
| 4.827e-02 | -3.03 | EGF (epidermal growth factor) | protein interactions | 1950 | 22 | 7 | 16036 | 2547 |
MAPKAPK2,ERBB2,NRG1,ERBB3,ADRBK1,EGFR,LMNA |
| 4.827e-02 | -3.03 | KCTD3 (potassium channel tetramerization domain containing 3) | protein interactions | 51133 | 22 | 7 | 16036 | 2547 |
EPN3,ARRB1,HSPB1,DNAJB2,SH3KBP1,SCRN2,DCUN1D1 |
| 4.827e-02 | -3.03 | C7orf25 (chromosome 7 open reading frame 25) | protein interactions | 79020 | 22 | 7 | 16036 | 2547 |
MX1,FYN,MYH14,CEP70,CRYM,DACT1,NGEF |
| 4.827e-02 | -3.03 | GORASP1 (golgi reassembly stacking protein 1) | protein interactions | 64689 | 22 | 7 | 16036 | 2547 |
PLK1,CASP3,CASP7,AGPS,CDK1,HIPK3,TMED2 |
| 4.828e-02 | -3.03 | V$PPAR_DR1_Q2 | MSigDB lists | V$PPAR_DR1_Q2 | 248 | 46 | 17758 | 2588 |
PAX6,SLC25A13,ARHGEF7,PNPLA2,TP53,GABRG2,C6orf106,ERBB2,CRABP2,C3orf18,PRR7,C1orf116,GBX2,SS18,PHYHIP,RNF128,CDK16,BHLHE41,RRBP1,TNFRSF12A,IQCD,SMYD5,NR2C1,TPCN1,ATP2B1,LAMP2,TGIF1,MMD,TMEM43,AGPS,ASXL1,TEF,KLK6,F12,ROR1,SLC25A5,PGF,INSR,C19orf66,MAP3K11,NR4A3,OVOL1,SPRY4,TMEM120A,COL16A1,ACOT7 |
| 4.828e-02 | -3.03 | V$ZIC1_01 | MSigDB lists | V$ZIC1_01 | 248 | 46 | 17758 | 2588 |
KIF3C,CERCAM,GABRG2,BAHD1,PDGFB,CYP26A1,LMNA,SAP130,FUT2,PPP1R10,SH3BP1,LMAN2L,ZDHHC12,FRAS1,BCL6,CDKN1B,ERBB3,ACSL4,HEXIM2,PACSIN1,NTN1,DVL2,CCDC88A,SEMA3B,CYP26B1,ATL1,CXXC5,WNT10B,S100A4,RGAG1,TMEM151A,COL7A1,MAP1B,DGKH,PGF,BTG1,KLF12,PTK7,OVOL1,GRIN2D,CTNND1,CDK18,NRG1,SPRY4,RGS14,DRD1 |
| 4.828e-02 | -3.03 | TGFBR1 (transforming growth factor, beta receptor 1) | protein interactions | 7046 | 189 | 39 | 16036 | 2547 |
CDK17,ACVR1,PLEKHJ1,XIAP,UBE2Z,RHPN2,TGFBR1,GNB2,ZFYVE9,CDK14,DAPK2,ANK1,CTNNB1,PLK4,ASH2L,PPP1CA,MAP3K7,ARL4D,STK35,HMMR,RHOA,DCAF6,RAB3B,ITCH,PIK3R1,CDC20,SCRIB,AURKB,RAB38,RANBP9,PLEKHB1,FNTA,ACVRL1,SAMD8,NUP37,OSR1,SAT2,RNF146,OCLN |
| 4.832e-02 | -3.03 | cellular amine metabolic process | biological process | GO:0044106 | 189 | 37 | 16441 | 2455 |
PLA2G4A,NQO1,DHPS,PSME2,PSMD7,ASL,PHOSPHO1,PSMD10,PSME1,PLA2G16,LPIN3,CDS1,PSMD1,PSMC2,SLC44A1,SLC44A2,ALDH7A1,GOT1,APIP,PSMA5,PSMB4,SAT1,CCBL2,SPTLC2,PSMA4,GPLD1,SLC44A3,PSMD3,DBI,PLA2G15,PNPLA6,MAOA,SLC27A1,SAMD8,CHPT1,SAT2,PSMC1 |
| 4.832e-02 | -3.03 | cellular biogenic amine metabolic process | biological process | GO:0006576 | 189 | 37 | 16441 | 2455 |
PLA2G4A,NQO1,DHPS,PSME2,PSMD7,ASL,PHOSPHO1,PSMD10,PSME1,PLA2G16,LPIN3,CDS1,PSMD1,PSMC2,SLC44A1,SLC44A2,ALDH7A1,GOT1,APIP,PSMA5,PSMB4,SAT1,CCBL2,SPTLC2,PSMA4,GPLD1,SLC44A3,PSMD3,DBI,PLA2G15,PNPLA6,MAOA,SLC27A1,SAMD8,CHPT1,SAT2,PSMC1 |
| 4.841e-02 | -3.03 | defense response | biological process | GO:0006952 | 1606 | 263 | 16441 | 2455 |
TXN,ACVR1,LGR4,GRIK2,TRIM5,AK7,DNAJC3,TAP1,CUL1,NRG2,GATA3,PSME1,IL18,CAMK1D,ELMOD2,CHST2,TP73,CALM2,PHYHIP,PSMD1,ELMO2,IL31RA,PIK3CA,AOX1,IRF2,PIK3CD,IL10RB,APOBEC3G,TNIP1,CASP9,BNIP3L,SLC35C1,AGO4,PRKAR2B,F12,RNF19B,MYOM1,PLCG1,LIMK1,MYLK,NOD2,NFKBIZ,RNASEL,F2RL1,GAB1,DDX58,THEMIS2,HLA-E,RAB23,SLC1A3,MECOM,ELF3,ZCCHC17,RPL39,FAM13B,DAPK1,TPST1,ALPK1,NCAM1,MAPK7,ULBP2,MAPKAPK3,MICB,CALM1,ANO6,ELK1,CYFIP2,PSMA4,RASA1,FAS,PELI2,ITPR1,RAET1L,MDH1,ARPC2,MAP3K5,IFIH1,RPS6KA3,TMEM173,IRF1,SPRED1,NLRX1,TUBB4B,RPS6KA1,BCL2L1,PRKACA,APOBEC3B,CD46,SP100,CDKN1B,DAB2IP,IFIT1,RASGEF1A,LGMN,MX1,RIPK2,APOBEC3D,LGALS8,PRKCQ,ATP1B1,ITPR3,IRS2,FYN,JAK1,DDOST,AXL,STAT1,NRG1,PRKAR1A,OTUD5,HSP90B1,TNRC6C,TRAF2,HERC5,APOBEC3H,PLD2,FGF19,LGALS3BP,ICAM1,HLA-A,CTNNBIP1,CXCL16,FAM111A,IRAK1,PTEN,CST3,ADAM15,MAPK11,ERBB3,MAP3K7,CNPY3,TRIM62,RASGRF1,PLSCR1,RAPGEF2,PIK3R1,NUB1,GRIN1,PARP4,FBXO9,YES1,FOS,TXK,HCP5,FGFR2,SLC35B3,DBI,GRIN2D,GPER1,SIGIRR,TNK1,UNC93B1,LMCD1,F11R,ITPR2,SDC1,PDGFB,TRIM68,SPTB,RPS6KA2,CTNNB1,SHC3,PSMC2,TNFRSF18,IL1RAP,RASGRP1,NLRP4,CD55,TRIM8,USP18,ITCH,NFE2L1,CR2,OPTN,MDK,PPP2R5D,PSMC1,LGALS3,HLA-F,RASA2,PSMD7,CALM3,NCKAP1,TEC,PHLPP1,DUSP5,BMP2,SPP1,KCNN4,PAK2,AHCY,HLA-C,PSMA5,EIF2AK1,IFIT3,EGFR,MAPKAPK2,CSF1,PHLPP2,NFKBIA,NLRC5,PLD1,JAK3,IFI6,APOL2,DRD1,IL15,PSME2,P2RX7,ERBB2,RASGRP3,IL27RA,SLC7A2,PDGFA,CYP4F11,PLCG2,BCL6,OAS3,NFKB2,F2R,FRS3,AKT1,CD40,DUSP4,SOCS3,PTGS2,STAT6,PSMD3,IRF7,SPTBN5,LTA4H,ANXA3,TAB3,CTSB,PSMD10,IL22RA1,HDAC9,IL17RB,ADRBK1,ADORA1,TRIM21,SYK,CAMK2G,ADAM17,PSMB4,IFITM3,NR4A1,TRIM35,FXR2,CD83,BCL10,CTSL,HLA-B,CD8A,SERPINA1,SCG2,PRCP,NMI,FGF18,DTX4,UBE2D2,ICOSLG,PTGES |
| 4.845e-02 | -3.03 | post-Golgi vesicle-mediated transport | biological process | GO:0006892 | 114 | 24 | 16441 | 2455 |
LAMP1,GCC2,SORT1,SH3D19,VAMP3,TGOLN2,ARFRP1,KIF13A,FTH1,RAB3IP,BBS2,OPTN,DOPEY2,AP1AR,AP1M2,WIPI1,STEAP2,RAB31,DNM2,SORL1,ARRB1,RAB29,RP2,MYO5A |
| 4.845e-02 | -3.03 | regulation of lipase activity | biological process | GO:0060191 | 114 | 24 | 16441 | 2455 |
SORT1,RHOA,CALM1,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,POR,ARF4,EGFR,PLIN5,TXK,EDNRA,CALM2,PLCG1,ADRBK1,CYR61,FGFR2,ARL1,ITPR1,PLCB2,RASGRP1,PRKAR1A |
| 4.853e-02 | -3.03 | racemase and epimerase activity, acting on carbohydrates and derivatives | molecular function | GO:0016857 | 10 | 4 | 16491 | 2452 |
GALM,DSE,GNE,GLCE |
| 4.853e-02 | -3.03 | GDP-dissociation inhibitor activity | molecular function | GO:0005092 | 10 | 4 | 16491 | 2452 |
ARHGDIB,RGS14,RANBP1,SH3BP4 |
| 4.853e-02 | -3.03 | dystroglycan binding | molecular function | GO:0002162 | 10 | 4 | 16491 | 2452 |
AGRN,MAP2,DAG1,GYLTL1B |
| 4.866e-02 | -3.02 | human chr20q11.22 | chromosome location | human chr20q11.22 | 32 | 7 | 26250 | 2805 |
CHMP4B,AHCY,PXMP4,FER1L4,TP53INP2,NECAB3,ITCH |
| 4.875e-02 | -3.02 | CUB | pfam domains | PF00431 | 48 | 12 | 16629 | 2504 |
PDGFC,PCOLCE,KREMEN2,ST14,MEGF8,BMP1,NETO2,ATRNL1,KREMEN1,DCBLD1,NRP2,TLL2 |
| 4.875e-02 | -3.02 | Hormone_recep | pfam domains | PF00104 | 48 | 12 | 16629 | 2504 |
THRB,NR3C1,NR1D2,NR4A1,THRA,PPARA,NR4A3,NR4A2,RARG,NR3C2,NR2C1,NR2C2 |
| 4.876e-02 | -3.02 | V$MEIS1AHOXA9_01 | MSigDB lists | V$MEIS1AHOXA9_01 | 111 | 23 | 17758 | 2588 |
PHF20L1,PDGFC,HOXB7,ASXL1,PIK3R1,FAM91A1,GBX2,IRX3,SCML1,CDKN2C,TFAP4,CNOT2,KLF12,PPP1R10,ANKS1B,TRIM69,TTC12,FLRT3,ZIC5,TFAP2A,ANKRD12,NDST3,JARID2 |
| 4.879e-02 | -3.02 | V$ATF3_Q6 | MSigDB lists | V$ATF3_Q6 | 236 | 44 | 17758 | 2588 |
CCNI,SORT1,IRX4,C6orf106,TNFRSF19,TIPRL,TSPAN7,CHPF,IRF2BPL,AKIRIN1,PAK6,CCND1,CCNA2,FLRT3,LMO4,MITF,FOSB,BCL6,DUSP10,TNFRSF12A,KLF9,DNAI1,DUSP1,OLFML2A,TRIM8,PTPRU,BNIP3L,AKAP3,ZFAND5,BSDC1,ABR,ABLIM2,MAP1B,CAMK2N2,AREG,SCG2,ZNF367,PITPNA,GEM,OSR1,STARD13,MAFF,RUSC1,EHD1 |
| 4.882e-02 | -3.02 | human chr19q13.3 | chromosome location | human chr19q13.3 | 74 | 13 | 26250 | 2805 |
DHDH,FUT2,FUT1,GYS1,EMP3,KLK6,DMWD,ERCC2,SULT2B1,CD33,ARHGAP35,KDELR1,DMPK |
| 4.885e-02 | -3.02 | DILUTE | prosite domains | PS51126 | 6 | 3 | 11866 | 1802 |
MYO5B,MYO5A,MYO5C |
| 4.885e-02 | -3.02 | BTG_2 | prosite domains | PS01203 | 6 | 3 | 11866 | 1802 |
BTG3,BTG1,TOB1 |
| 4.885e-02 | -3.02 | FAD_PCMH | prosite domains | PS51387 | 6 | 3 | 11866 | 1802 |
AGPS,AOX1,XDH |
| 4.885e-02 | -3.02 | G_DYNAMIN_1 | prosite domains | PS00410 | 6 | 3 | 11866 | 1802 |
MX1,DNM1L,DNM2 |
| 4.885e-02 | -3.02 | GED | prosite domains | PS51388 | 6 | 3 | 11866 | 1802 |
MX1,DNM1L,DNM2 |
| 4.885e-02 | -3.02 | BTG_1 | prosite domains | PS00960 | 6 | 3 | 11866 | 1802 |
BTG3,BTG1,TOB1 |
| 4.886e-02 | -3.02 | RAS_GTPASE_ACTIV_1 | prosite domains | PS00509 | 14 | 5 | 11866 | 1802 |
DAB2IP,IQGAP3,IQGAP1,RASA2,RASA1 |
| 4.886e-02 | -3.02 | KEGG_PYRUVATE_METABOLISM | MSigDB lists | KEGG_PYRUVATE_METABOLISM | 39 | 10 | 17758 | 2588 |
ACACB,ALDH2,ACYP1,HAGHL,AKR1B1,ALDH7A1,GLO1,MDH1,ALDH3A2,DLAT |
| 4.886e-02 | -3.02 | ONO_AML1_TARGETS_DN | MSigDB lists | ONO_AML1_TARGETS_DN | 39 | 10 | 17758 | 2588 |
RUNX2,RBL1,SELL,IL17RA,RUNX3,TNFRSF18,SGOL1,CD81,CASP4,SOCS3 |
| 4.886e-02 | -3.02 | PID_RET_PATHWAY | MSigDB lists | PID_RET_PATHWAY | 39 | 10 | 17758 | 2588 |
IRS2,RHOA,DOK4,PIK3R1,RET,PIK3CA,PRKACA,BCAR1,GAB1,RASA1 |
| 4.886e-02 | -3.02 | VIRAL_REPRODUCTION | MSigDB lists | VIRAL_REPRODUCTION | 39 | 10 | 17758 | 2588 |
TOP2A,TNIP1,ITCH,WWP1,MDFIC,GFI1,CD81,CTBP1,APOBEC3G,WWP2 |
| 4.887e-02 | -3.02 | JUN (jun proto-oncogene) | protein interactions | 3725 | 217 | 44 | 16036 | 2547 |
RUNX2,EPAS1,GGA1,TSC22D3,TRAF2,STRN4,ETS1,ELF3,HDAC9,M6PR,TOP2A,RB1,APLP2,RPS6KA2,IRAK1,GATA2,GTF2F2,BCL6,MAPK11,ETV4,NCOA2,SIRT1,TGIF1,NR3C1,ITCH,STAT4,PLEKHO1,CASP9,NFE2L1,FOS,MAPK8IP1,BTG1,NCOA3,ETS2,HOXA9,STAT6,STAT1,PIAS2,ARRB1,HDAC1,KPNA2,HMGA1,SOX8,PPP2R2D |
| 4.889e-02 | -3.02 | FZ | prosite domains | PS50038 | 23 | 7 | 11866 | 1802 |
COL18A1,ROR1,FZD5,FZD4,FZD7,FZD6,SMO |
| 4.893e-02 | -3.02 | rough endoplasmic reticulum membrane | cellular component | GO:0030867 | 19 | 6 | 17570 | 2579 |
SEC61B,PLOD3,PLOD2,BCAP31,DNAJC3,SUCO |
| 4.898e-02 | -3.02 | virus receptor activity | molecular function | GO:0001618 | 70 | 16 | 16491 | 2452 |
LAMP1,PVRL4,CD55,CR2,F11R,DAG1,ICAM1,XPR1,CD46,SCARB2,IDE,PVRL2,AXL,SIVA1,ITGAV,NCAM1 |
| 4.904e-02 | -3.02 | IL-5 Signaling Pathway | WikiPathways | WP127 | 69 | 17 | 4455 | 729 |
PLA2G4A,AKT1,RPS6KA1,PIK3R1,CBL,ELK1,ICAM1,CTNNB1,JAK1,NFKBIA,DNM2,STAT1,BAX,CDKN1B,PIM1,RAP1GAP,SYK |
| 4.906e-02 | -3.01 | transcription factor activity, transcription factor binding | molecular function | GO:0000989 | 581 | 101 | 16491 | 2452 |
ELK4,TRIM24,CRYM,LMCD1,GATA3,TAF6L,LPIN3,MXD1,PER2,CCND1,SAP130,HELZ2,SS18,HSF2,SP100,CTNNB1,ZCCHC12,IL31RA,CRY2,NFKB2,MED30,THRB,SIRT1,SMARCA2,KCNIP3,CITED4,ASXL1,DRAP1,UXT,CDYL,NFE2L1,HTATIP2,LOXL2,LDB2,GTF2A2,SP4,ARHGAP35,AHRR,HSF4,JADE1,KLF12,WWTR1,TLE1,HDAC1,NRG1,NFKBIZ,E2F8,ARNT,CBX4,NR2C2,AES,NOTCH2,PKN1,AIP,PSIP1,HDAC9,WWP2,ELF3,ZNF212,GBX2,TFAP4,ZFX,E2F7,RB1,TAF1B,BHLHE41,TFAP2A,BRD7,CITED2,WNT3A,NCOA2,MED22,NFE2L3,TGIF1,ELK3,DCAF6,NR3C1,PPARA,FHL2,MAML2,NFIB,BCL10,CNOT2,PITX2,BTG1,NCOA3,SERTAD2,ATXN7L3,SETD3,TBX18,RAP2C,NMI,NAB2,TADA2B,PIAS2,SFMBT1,HMGA1,TOB1,CTBP1,USP16,KLF7 |
| 4.906e-02 | -3.01 | MODULE_36 | MSigDB lists | MODULE_36 | 152 | 30 | 17758 | 2588 |
CDS2,TCFL5,CASP9,ETV5,TEP1,KLK6,CRABP2,CBL,BARD1,PER2,BCAR3,PIAS3,SNTA1,PCNA,PROM1,GPRC5B,KCNK1,PEX2,DAPK1,CDKN1B,ASH2L,HSPA13,MTMR11,PDE4D,ARF6,ATP6V1C1,RPGR,SCYL3,NCOA2,DLAT |
| 4.910e-02 | -3.01 | TRIM25 (tripartite motif containing 25) | protein interactions | 7706 | 76 | 18 | 16036 | 2547 |
DDX58,TRIM8,GRIK2,SUZ12,AMFR,CDA,RNPEP,VCP,KIF5B,PITX2,PCNA,UAP1,STK38,UBE2D2,OTUB2,KLF5,ERCC2,TFG |
| 4.915e-02 | -3.01 | RAB1A (RAB1A, member RAS oncogene family) | protein interactions | 5861 | 129 | 28 | 16036 | 2547 |
TXN,ENO2,RFK,TUBB4B,RUSC2,ASB9,PSMD7,PDIA3,CAPNS1,RAB6A,ATP1B1,PRRC1,BCAP31,RABGGTA,KDSR,TBC1D17,ATP1A1,ATP5H,OCRL,RANBP1,RAP2C,RAB31,ARRB1,RPN2,ATP1B3,TECR,PLIN3,TMED2 |
| 4.918e-02 | -3.01 | genital_tract-extragonadal-germ_cell_tumour-seminoma | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-seminoma | 66 | 15 | 17775 | 2585 |
LTBP1,PLCG1,CTNNB1,FAT4,LLGL2,PTEN,TMEM41B,CD9,TP53,SPRY4,CBL,IDH1,MYLIP,KCNC4,NEB |
| 4.918e-02 | -3.01 | maxilla | COSMIC cancer mutations | maxilla | 66 | 15 | 17775 | 2585 |
GNAS,SMARCA2,CTNNB1,HSPG2,FGFR2,COG2,PTEN,PIK3CA,TP53,SMO,MAP3K7,JAK3,EGFR,GINS4,DDX23 |
| 4.919e-02 | -3.01 | membrane raft assembly | biological process | GO:0001765 | 10 | 4 | 16441 | 2455 |
PACSIN2,FLOT2,EMP2,FLOT1 |
| 4.919e-02 | -3.01 | meiotic spindle organization | biological process | GO:0000212 | 10 | 4 | 16441 | 2455 |
TUBG1,AURKA,ESPL1,ASPM |
| 4.919e-02 | -3.01 | positive regulation of membrane potential | biological process | GO:0045838 | 10 | 4 | 16441 | 2455 |
PIAS3,SLC9A3R2,VCP,DRD1 |
| 4.919e-02 | -3.01 | metanephric tubule morphogenesis | biological process | GO:0072173 | 10 | 4 | 16441 | 2455 |
HES1,SOX8,LGR4,SOX9 |
| 4.919e-02 | -3.01 | endothelial cell chemotaxis | biological process | GO:0035767 | 10 | 4 | 16441 | 2455 |
NOV,EGR3,NR4A1,CORO1B |
| 4.919e-02 | -3.01 | regulation of steroid hormone biosynthetic process | biological process | GO:0090030 | 10 | 4 | 16441 | 2455 |
BMP2,ATP1A1,IGF1R,POR |
| 4.919e-02 | -3.01 | positive regulation of hormone metabolic process | biological process | GO:0032352 | 10 | 4 | 16441 | 2455 |
GATA3,IGF1R,POR,ARNT |
| 4.919e-02 | -3.01 | spindle elongation | biological process | GO:0051231 | 10 | 4 | 16441 | 2455 |
KIF23,RACGAP1,AURKB,PRC1 |
| 4.919e-02 | -3.01 | regulation of epithelial cell proliferation involved in prostate gland development | biological process | GO:0060768 | 10 | 4 | 16441 | 2455 |
CDKN1B,EAF2,NKX3-1,CTNNB1 |
| 4.919e-02 | -3.01 | development of secondary sexual characteristics | biological process | GO:0045136 | 10 | 4 | 16441 | 2455 |
IRF2BPL,NCOA3,AREG,BAX |
| 4.919e-02 | -3.01 | positive regulation of neuron migration | biological process | GO:2001224 | 10 | 4 | 16441 | 2455 |
KIF20B,DAB2IP,SEMA3A,RAPGEF2 |
| 4.919e-02 | -3.01 | regulation of Wnt signaling pathway, planar cell polarity pathway | biological process | GO:2000095 | 10 | 4 | 16441 | 2455 |
NPHP3,ANKRD6,DACT1,NKD1 |
| 4.919e-02 | -3.01 | fatty acid transmembrane transport | biological process | GO:1902001 | 10 | 4 | 16441 | 2455 |
PRKAA2,ACACB,PRKAG2,CPT2 |
| 4.919e-02 | -3.01 | vagina development | biological process | GO:0060068 | 10 | 4 | 16441 | 2455 |
NCOA3,MERTK,AXL,BAX |
| 4.919e-02 | -3.01 | regulation of toll-like receptor 3 signaling pathway | biological process | GO:0034139 | 10 | 4 | 16441 | 2455 |
WDFY1,FLOT2,F2RL1,FLOT1 |
| 4.923e-02 | -3.01 | V$NFKB_Q6_01 | MSigDB lists | V$NFKB_Q6_01 | 224 | 42 | 17758 | 2588 |
BMF,TP53,NDRG2,IL27RA,TRIB2,DDR1,NFAT5,BMP2K,ICAM1,RND1,RNF220,IL6ST,SLC44A1,MITF,CD70,RFX5,NTN1,NFKB2,SEMA3B,SUN2,TGIF1,TNIP1,NR3C1,ATP1B1,ILK,CD40,PNKD,CNTNAP1,TRIM47,PTPRJ,STAT6,RAP2C,NFKBIA,MAP3K11,UACA,FAM117A,GRIN2D,SP6,GEN1,SHOX2,JAK3,PTGES |
| 4.924e-02 | -3.01 | Keratan sulfate biosynthesis | REACTOME pathways | R-HSA-2022854 | 28 | 8 | 8202 | 1235 |
B3GNT7,SLC35D2,B3GNT2,B4GAT1,B4GALT3,B4GALT4,ST3GAL1,CHST2 |
| 4.924e-02 | -3.01 | Energy dependent regulation of mTOR by LKB1-AMPK | REACTOME pathways | R-HSA-380972 | 28 | 8 | 8202 | 1235 |
PRKAA2,TSC1,PRKAG2,PRKAA1,STRADB,CAB39,RHEB,RRAGD |
| 4.926e-02 | -3.01 | FES (FES proto-oncogene, tyrosine kinase) | protein interactions | 2242 | 36 | 10 | 16036 | 2547 |
IRS2,DPYSL5,JAK1,PIK3R1,PLXNA1,JAK3,BCAR1,RASA1,EGFR,MDFI |
| 4.926e-02 | -3.01 | MMP7 (matrix metallopeptidase 7) | protein interactions | 4316 | 36 | 10 | 16036 | 2547 |
GID8,CNOT2,RMND5A,SPP1,MBP,SERPINA1,CNOT8,CNOT6L,RANBP9,ZBTB33 |
| 4.926e-02 | -3.01 | ITK (IL2-inducible T-cell kinase) | protein interactions | 3702 | 36 | 10 | 16036 | 2547 |
PLCG1,FYN,IBTK,PLCG2,ERBB2,TGFBR1,KPNA2,ERBB3,CBL,EGFR |
| 4.937e-02 | -3.01 | REACTOME_OPIOID_SIGNALLING | MSigDB lists | REACTOME_OPIOID_SIGNALLING | 77 | 17 | 17758 | 2588 |
PLA2G4A,CALM1,GNAL,CALM3,PRKAR2B,ITPR2,ITPR3,PRKACA,GNB2,CALM2,GNB5,ADRBK1,PDE4D,PPP1CA,PLCB2,PPP2R5D,PRKAR1A |
| 4.937e-02 | -3.01 | PcG protein complex | cellular component | GO:0031519 | 44 | 11 | 17570 | 2579 |
SIRT1,PCGF5,ASXL1,SUZ12,CBX6,H2AFY,PHF1,CBX7,CBX4,JARID2,PHC1 |
| 4.940e-02 | -3.01 | shoulder | COSMIC cancer mutations | shoulder | 404 | 71 | 17775 | 2585 |
EXPH5,ARHGAP11A,ILDR1,UGT8,TP53,FLT3,PAK6,CTNNB1,TACC2,MITF,SMO,PIK3CA,STEAP3,PIK3CD,LMAN1,PTPRE,CPE,AKT1,TNS1,SLC17A5,IDH1,FANCE,ATP13A2,TNS4,EPHA10,PLEKHG6,DUOX1,PLCH1,PTPRJ,PTK7,COBL,HSP90B1,MRC2,FRMD4A,TMTC3,MACC1,RASSF7,LRP4,HLA-A,LMNA,MECOM,SNTA1,KIF5B,MDM1,PTEN,GPC3,FBXO7,SGK1,MYO5A,SUN2,ADAMTS2,CEP89,PIK3R1,PTPRH,LRRC66,COL7A1,KDM3A,NUBP1,GNA11,FOXL1,EGFR,PTPRF,RGS9,PLEKHH2,BANK1,SLC4A3,ARAP1,CSTF2,ALPK3,PER3,HIPK3 |
| 4.944e-02 | -3.01 | regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050730 | 207 | 40 | 16441 | 2455 |
NF2,IBTK,IL15,TP53,IL18,TEC,PDGFB,FLT3,ICAM1,PDGFA,APLP2,ADORA1,IL6ST,IL31RA,PAK2,TNFRSF18,ERBB3,WNT3A,SYK,DVL2,SOCS5,PDGFC,HES1,ADAM17,RIPK2,DMTN,YES1,CD40,EGFR,FYN,GPRC5B,SEMA4D,PLPP3,RAP2C,NOD2,NRG1,EFNA5,LRRK1,EFNA1,CD81 |
| 4.947e-02 | -3.01 | basal_cell_carcinoma | COSMIC cancer mutations | basal_cell_carcinoma | 24 | 7 | 17775 | 2585 |
NOTCH2,CTNNB1,AKT1,EGFR,SMO,PIK3CA,TP53 |
| 4.947e-02 | -3.01 | neuroendocrine_carcinoma | COSMIC cancer mutations | neuroendocrine_carcinoma | 24 | 7 | 17775 | 2585 |
ERBB2,AKT1,FLT3,EGFR,RET,PIK3CA,TP53 |
| 4.947e-02 | -3.01 | KEGG_BASAL_CELL_CARCINOMA | MSigDB lists | KEGG_BASAL_CELL_CARCINOMA | 55 | 13 | 17758 | 2588 |
BMP2,WNT10B,CTNNB1,FZD4,SMO,TP53,TCF7,WNT3A,FZD5,APC2,DVL2,FZD6,FZD7 |
| 4.947e-02 | -3.01 | GARCIA_TARGETS_OF_FLI1_AND_DAX1_UP | MSigDB lists | GARCIA_TARGETS_OF_FLI1_AND_DAX1_UP | 55 | 13 | 17758 | 2588 |
NCKAP5,NEIL1,INPPL1,KCNMB4,STIM1,HLA-E,ATP7B,WDR19,KDELR3,ADCK5,HMGCL,PLIN3,PGAP1 |
| 4.947e-02 | -3.01 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP | 55 | 13 | 17758 | 2588 |
SOD1,CTGF,PRSS23,ITGB8,NGFRAP1,NDRG1,BNIP3L,FLOT1,TP53I11,SGCB,EFNB1,RHOB,PRDX4 |
| 4.947e-02 | -3.01 | WIERENGA_STAT5A_TARGETS_GROUP2 | MSigDB lists | WIERENGA_STAT5A_TARGETS_GROUP2 | 55 | 13 | 17758 | 2588 |
KLF2,SPP1,CA2,GNPTAB,COL6A1,MAPK13,AK3,TANC1,ABCA1,CKAP4,CD83,GABARAPL1,LAMP3 |
| 4.950e-02 | -3.01 | SPTBN1 (spectrin, beta, non-erythrocytic 1) | protein interactions | 6711 | 97 | 22 | 16036 | 2547 |
MOB4,SOD1,NF2,UBASH3B,MYBL2,CUL1,NENF,TGFBR1,PYGO1,FBXO6,CBL,PRKACA,WEE1,ANK1,TRAF3IP1,STAT1,PRKCDBP,TUBG1,PDE4D,PACSIN1,HSPB1,CAPN1 |
| 4.968e-02 | -3.00 | MORF_RAB5A | MSigDB lists | MORF_RAB5A | 94 | 20 | 17758 | 2588 |
SYPL1,DDB2,PSMB4,GPR107,TCEB2,PSMD7,MORF4L2,MYL12A,BCAP31,TAPBP,DNPEP,EFR3A,PSMC2,TMBIM6,NPTN,MAD2L1BP,PSMC1,MYL12B,TMED2,EBAG9 |
| 4.968e-02 | -3.00 | CAHOY_OLIGODENDROCUTIC | MSigDB lists | CAHOY_OLIGODENDROCUTIC | 94 | 20 | 17758 | 2588 |
FAM89A,UGT8,CRYM,BACE1,CRIP2,EFHD2,PRKCQ,CNTNAP2,G2E3,PRKAG2,CTGF,FA2H,P4HA2,FBXO7,ERBB3,SOX8,AHR,NR2C1,USP16,TUBA4A |
| 4.972e-02 | -3.00 | HSPA1L (heat shock 70kDa protein 1-like) | protein interactions | 3305 | 113 | 25 | 16036 | 2547 |
SIRT1,BAG4,INPPL1,SHMT1,FIGNL1,LPGAT1,UBASH3B,CUL4B,CDC20,TP53,CUL1,CAMK1D,NUCB2,VASH1,CBL,HDAC6,MRPS36,DENND2D,EPN3,ALDH3B1,RRBP1,TRAF3IP1,DCUN1D1,TUBG1,DLAT |
| 4.978e-02 | -3.00 | serotonin degradation | BIOCYC pathways | META_PWY-6313 | 5 | 3 | 907 | 172 |
MAOA,ALDH2,ALDH3A2 |
| 4.978e-02 | -3.00 | chondroitin biosynthesis | BIOCYC pathways | META_PWY-6566 | 5 | 3 | 907 | 172 |
CHSY3,CSGALNACT1,CHPF |
| 4.978e-02 | -3.00 | chondroitin and dermatan biosynthesis | BIOCYC pathways | HUMAN_PWY-6566 | 5 | 3 | 907 | 172 |
CHSY3,CSGALNACT1,CHPF |
| 4.981e-02 | -3.00 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 200 | 38 | 17758 | 2588 |
GALK1,LGALS3,NDRG1,SERPINB9,FBXO6,PRKACA,IL18R1,PDIA4,CKAP5,TOP2A,RB1,SIVA1,CAPG,TUBG1,CKS1B,SULT2B1,CRTAP,S100A6,PGM1,LOC81691,GGH,NUSAP1,ANLN,MEST,MRPS36,PRDX4,MAPKAPK2,CDKN2AIPNL,PAFAH1B3,ACVRL1,CCDC6,DCK,SPAG7,ARFGAP3,STK39,TMEM159,ACOT7,XDH |
| 4.982e-02 | -3.00 | CDK4 (cyclin-dependent kinase 4) | protein interactions | 1019 | 140 | 30 | 16036 | 2547 |
IL15RA,CDKN1C,FOXM1,GUSB,CUL4B,CUL1,PSMD10,CAPNS1,TGFBR1,PKM,ZNF219,VCP,CDK5R1,CCND1,CDKN2C,RB1,PCNA,CCNA2,RBL1,H1F0,ANKRD12,CDKN1B,PPP1CA,RCAN3,JAK3,HOOK1,CDKN2D,SHOX2,NCOA2,PRKAR1A |
| 4.984e-02 | -3.00 | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 176 | 34 | 17758 | 2588 |
CASP3,MTM1,MPZL1,XYLT1,CUL4B,NDC80,KCTD12,FAM78A,FAM91A1,FAM101B,BCAP31,CD46,ATP6V0B,ZNF75D,FAM13B,TAX1BP3,RASGEF1A,SLC16A5,MAP3K3,LAMP2,RFK,TACC1,KIAA0040,HEATR5A,IDH1,ZMPSTE24,SGPP1,DGCR2,PRDX3,APPL2,HDAC1,DHTKD1,GRAMD1C,CMTM4 |
| 4.984e-02 | -3.00 | KEGG_CALCIUM_SIGNALING_PATHWAY | MSigDB lists | KEGG_CALCIUM_SIGNALING_PATHWAY | 176 | 34 | 17758 | 2588 |
GNAL,ERBB2,CALM3,P2RX7,ITPR2,PRKACA,GRM5,CALM2,PLCG2,TRPC1,CACNA1D,ERBB3,PHKA2,F2R,PLCB2,PHKG2,CAMK2G,ATP2B1,P2RX4,CALM1,GRIN1,ITPR3,SLC25A5,GNA11,EGFR,EDNRA,GNAS,PLCG1,SLC25A4,MYLK,ITPR1,GRIN2D,ITPKA,DRD1 |
| 4.987e-02 | -3.00 | extraskeletal | COSMIC cancer mutations | extraskeletal | 942 | 155 | 17775 | 2585 |
SLC35D2,BCAM,KIAA1462,IBTK,CRYM,PNPLA2,RET,FHDC1,GATA3,PLAC1,ITPR2,PLXNA1,DNER,NAPG,CYP1A1,CTNNB1,STIM1,STEAP2,PIK3CA,ANKRD12,TLN2,TFG,TIAM1,MGAT5,NEB,ZNF462,SPEF2,CELSR2,ACBD3,RGAG1,TNS1,IDH1,COL12A1,VCP,KDM4D,MAN2A2,MFAP3L,HS6ST1,TRAM2,AREG,ATP7B,MYLK,LRIG1,MADD,RAB11FIP1,IARS2,UNC5B,PDPR,PSMC1,SCN5A,INPPL1,CDK17,RUNX2,CHCHD7,TBC1D1,DGKQ,SLC25A27,PGAP1,RB1,AIM1L,IGF1R,MEGF8,FBXL14,PIKFYVE,MOXD1,DGKG,IGSF3,KIAA1841,USP31,DCHS1,ATP8B3,DPYSL4,EGFR,PLIN5,PRX,FECH,AP1AR,INSR,COQ10A,CGREF1,DYSF,EGFL7,PLIN3,TOB1,GAS2L1,NCKAP5,KCNAB3,GALNT12,SLC2A8,CCDC110,ATP2C2,TP53,PKP2,ERBB2,TMEM19,DDR1,FLT3,C1orf116,PDGFA,SS18,SMO,TSPAN1,PHKA2,NR2C1,SULF2,AKT1,PTPRU,TMEM43,SYNE2,UTRN,NUSAP1,C15orf39,DOCK5,ATP13A2,PEX5,RTN4RL1,WFS1,SECTM1,SIPA1L1,OVOL1,ABCA1,ARHGEF3,SHPRH,TRAF2,LRP4,OSGIN2,NKRF,NTAN1,DNAH3,PARM1,TEAD3,FUT2,LLGL2,PTEN,TRIM3,KLF9,IQGAP3,MED22,HCN3,LONRF3,ERMAP,CTNNAL1,DENND1B,PIK3R1,RC3H2,GRIN1,AKAP3,RNPEP,KLHL2,SWAP70,DGCR2,FGFR2,WDR62,JARID2,GOLGB1 |
| 4.988e-02 | -3.00 | regulation of ion transport | biological process | GO:0043269 | 579 | 101 | 16441 | 2455 |
KCNAB3,ATP8A1,CACNA2D2,PKP2,P2RX7,PRKACA,CACNB4,PDGFB,PER2,CALM2,NKAIN3,CTNNB1,STIM1,CABP1,DPYSL2,PLCG2,KCNS3,DLG1,DNM2,TRPC1,CRY2,TWIST1,PDE4D,TMEM37,ACSL4,SCN2A,F2R,HSPA2,SCN3A,CHP1,PPIF,CLCN3,KCNIP3,AKT1,UTRN,NKAIN1,ATP1B1,CLCN2,IRS2,PTGS2,PLCG1,ATP1A1,WFS1,MYLK,CAB39,SARAF,SLC31A2,PRSS8,TCAF1,SCN5A,PINK1,LGALS3,SERPINE2,CD63,UBASH3B,FXYD3,CALM3,ANO9,KCNC4,ANO1,ICAM1,WWP2,KIF5B,SNTA1,ADORA1,CA2,GNB5,KCNK5,DAPK1,BAX,SGK3,SGK1,FXYD5,TSPAN13,CACNA1D,SYK,TPCN1,CAMK2G,MYO5A,HCN3,P2RX4,KCNJ12,RASGRF1,RHOA,RAB3B,CASK,CALM1,ANO6,GRIN1,VAMP3,HTT,NETO2,PKD2,STK39,GPER1,FHL1,ATP1B3,JAK3,TRPC3,DRD1,DMPK |
| 4.988e-02 | -3.00 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN | 194 | 37 | 17758 | 2588 |
NQO1,DNAJB2,MORC4,INTS8,SEPT4,SLC20A1,KTN1,FZD6,CCND1,TM9SF2,CTSC,METTL7A,FOSB,CD70,SELK,NFU1,NCOA2,DVL2,SEC23A,PGM1,PTPN18,UBE2A,SPATA13,LITAF,PIP4K2C,NUSAP1,IFIT3,TYSND1,SGPP1,SWAP70,SYT7,TIMM8A,CCDC6,IRF7,CHPT1,PSMC1,SRSF9 |
| 4.988e-02 | -3.00 | GSE17721_0.5H_VS_24H_CPG_BMDM_DN | MSigDB lists | GSE17721_0.5H_VS_24H_CPG_BMDM_DN | 194 | 37 | 17758 | 2588 |
PLA2G4A,GCLM,LZTFL1,ARHGEF3,AGRN,PARP14,HLA-E,CD82,PPFIBP2,TAP1,DGKA,PKP2,REPS1,SUSD2,FAM160A2,LMO4,FAM20B,TRIM21,MDFIC,SNX10,MYLIP,CYP1B1,LAMP2,ENPP4,TNIP1,USP18,RAD17,BCL2L13,RNF19B,ANTXR1,CYB5A,CRTC2,HLA-B,FAM114A1,DGAT2,CHPT1,ABCA1 |
| 4.988e-02 | -3.00 | GSE27786_BCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_BCELL_VS_NEUTROPHIL_DN | 194 | 37 | 17758 | 2588 |
PCOLCE,KLK10,GRHL2,ARHGEF7,BIK,NRG2,MPP5,TEX2,BAIAP3,CYP26A1,CDK14,FUT2,KNDC1,SGK3,PRC1,SERINC2,ACOX2,NPTXR,OSBPL7,CITED2,ITM2C,SNED1,GPX4,AMOTL2,UFD1L,PRKRA,TMEM30A,HOXA9,CORO1C,AXL,FAM114A1,STK39,SERPINB6,PKD2,AKNA,TMEM120A,UNC5B |
| 4.988e-02 | -3.00 | GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP | MSigDB lists | GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP | 194 | 37 | 17758 | 2588 |
FRMD4A,CDH22,PYROXD2,KIF2C,EGR3,HDAC6,SRPX2,ART5,ARHGEF10L,RB1,ST5,ICAM5,ELF5,ESPN,MXD3,APIP,KNTC1,ANKRD9,GCNT1,SIRT1,PBK,SERTAD3,BLVRA,CCNF,GOLT1A,DHX32,DCAF10,CARHSP1,DUOX1,DCK,CDCA5,TRAF3IP1,CTNND1,DMWD,CMPK2,GAB1,SAT2 |
| 4.988e-02 | -3.00 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 194 | 37 | 17758 | 2588 |
SORT1,CDK17,PAPSS2,NFKBIE,LRRFIP2,SERPINE2,CYP2J2,CHST2,MYO5C,BTG3,TRANK1,RUNDC3B,CKS1B,RFX5,ECE1,CACNA1D,SNX10,HSPA2,LAMP3,CKS2,PLEKHA6,SLC37A1,KIAA0040,PLAUR,SAV1,CD40,OPTN,PRDX4,CASP7,MAP2,C19orf66,KBTBD2,ALPK3,GLA,MAD2L1BP,AHR,IRF1 |
| 4.989e-02 | -3.00 | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | 182 | 35 | 17758 | 2588 |
MAN2B2,CCDC109B,PAX6,CAST,TSC22D3,ITGA6,BTN3A1,CDIPT,FAM46C,KHNYN,FAM46A,SLC16A6,MGAT4A,IL6ST,SMAGP,GCC2,COQ10B,PIK3R1,PTGER4,LITAF,TCF7,SRSF5,PLEKHB1,OPTN,FYN,STK38,KBTBD2,CSGALNACT1,SFMBT1,ARRB1,FAM117A,FHL1,PPP2R2D,TOB1,ARHGEF9 |
| 4.989e-02 | -3.00 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN | 182 | 35 | 17758 | 2588 |
GAS2L1,GAA,EPAS1,PTTG1,OSGIN2,C5orf30,GRK6,ANK1,MUC16,CTGF,PAIP2B,RGS3,CLDN4,RPN2,BUB1,USP1,ALDH7A1,OSBPL7,GCA,PTPRH,FHL2,PDE5A,MTRF1L,LRRC1,FANCE,ARHGAP35,DCAF10,FUCA1,TRAM2,DNAJC10,PEX5,ACADSB,AGPAT2,DCUN1D1,SLC25A30 |
| 4.989e-02 | -3.00 | TGFB_UP.V1_UP | MSigDB lists | TGFB_UP.V1_UP | 182 | 35 | 17758 | 2588 |
CDK17,RUSC2,CYP2J2,EPHA4,LMCD1,PDGFB,SPSB1,HTR1D,PDGFA,ANK1,RGS12,CTGF,PAIP2B,KCNN4,DACT1,SGK1,CCDC82,PIK3CD,CYP26B1,CDKN2AIP,ELK3,MMD,RAPGEF2,RNF19B,RHOB,SEC14L2,TNS4,ETS2,FAT4,LTBP2,F2RL1,COL16A1,PKIA,KLF7,ABCG1 |
| 4.991e-02 | -3.00 | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP | MSigDB lists | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP | 188 | 36 | 17758 | 2588 |
OTUD5,MRC2,TRIP10,ITGA6,SELL,FAM91A1,B4GALT4,SPSB1,PNPLA5,RASSF8,RCN1,PHYHIP,FRYL,MCF2L,VASN,BDH1,PRKCI,FAM102A,TIAM1,SMC4,THRB,MBP,USP18,MBNL3,PGBD1,RAB3IP,DGKE,NFIX,SGPP1,DUOX1,PRKAG2,PIAS2,INPP4B,STK39,KIF12,XDH |
| 4.991e-02 | -3.00 | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 188 | 36 | 17758 | 2588 |
SPRED1,CPEB4,TMEM217,GNPDA1,FAM129B,PYROXD2,CUL4B,CDCA8,DHRS3,ART5,LMNA,NRP2,PDGFA,NOV,PSMD1,VAT1,TNFRSF12A,LMAN1,HMMR,ATL1,UXT,FRMD4B,SOCS3,DHX32,IL1R1,SYT7,WWTR1,NFKBIZ,RNASEL,F2RL1,CCNB2,NR3C2,HOXC13,FGD1,PRKAR1A,NGEF |
| 4.991e-02 | -3.00 | GSE1432_1H_VS_6H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_6H_IFNG_MICROGLIA_UP | 188 | 36 | 17758 | 2588 |
HECA,AVPI1,FARP1,SSH1,LGR4,XYLT1,CTDSPL,RASGRP3,STIL,COX7A2,PICK1,SLC25A36,LLGL2,BDH1,FUT8,TAX1BP3,CLCN3,PGM1,MPP1,MRS2,MEST,SESN1,NDRG3,STK17B,NMT2,RHOB,SOCS3,CNTNAP1,WIPI1,PPM1H,MAOA,AURKA,PLXND1,CCNB2,RTN3,SRSF9 |
| 4.991e-02 | -3.00 | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN | 188 | 36 | 17758 | 2588 |
SERPINE2,GCAT,SUZ12,TMEM41B,GPSM2,CENPN,BTG3,PFKL,PRICKLE3,CYP2S1,RANBP1,PSMC2,PCYOX1,AHCY,TIAM1,NR2C1,NUP85,PLK1,PPIF,SYPL1,FIGNL1,PBK,HEATR5A,XRCC6BP1,CMTM7,PRIM1,PRDX4,NT5C2,BOLA3,UAP1,PRDX3,RYK,STK39,SPCS3,ATP6V1C1,NDFIP1 |
| 4.991e-02 | -3.00 | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN | 188 | 36 | 17758 | 2588 |
HECA,BMF,PINK1,JKAMP,RPS6KA1,DCAF7,CCM2,SMARCAL1,CDIPT,DPP8,C11orf95,GNB2,KIAA1147,PIK3CD,CTDSP2,SYK,FAM134C,ORAI2,TAF5,TRIM8,TACC1,UBAC1,TNFAIP8L1,CBL,ILK,ADRBK2,FUCA1,PTPRJ,GDE1,STK38,RIN3,ZDHHC7,CAB39,ARRB1,CTNND1,SRSF9 |
| 4.991e-02 | -3.00 | GSE27786_LIN_NEG_VS_NKTCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NKTCELL_DN | 188 | 36 | 17758 | 2588 |
CDK17,DHPS,CAST,PTTG1,TAP1,ETNK1,KCTD12,IL13RA1,PLA2G16,SLC20A1,IRF2BPL,INPP5E,FAM46A,CD22,MGAT4A,BDH1,PARP9,POU6F1,TNIP1,SAT1,TRIM35,CNOT2,SLC25A4,RCBTB2,KBTBD2,STK38,NMI,IRF7,CYP2U1,ITGAV,RGS14,SEMA3A,RARG,RNF146,JARID2,ADAMTS16 |
| 4.991e-02 | -3.00 | GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN | 188 | 36 | 17758 | 2588 |
ZMAT1,PAPSS2,CPEB4,TMEM41B,CERCAM,PDCL,PDIA3,P2RX7,DNAJB11,MPP5,BAIAP3,DHRS3,MGAT1,SMO,UBE2J1,BCL6,DUSP10,CLIP2,FGFR1OP2,DDB2,DBR1,GALNT7,BCL2L13,CYFIP2,ZFAND5,ALDH3B1,CCNB3,RBL1,SLC2A6,PNPLA6,IRF7,CMPK2,CBX4,RRAGD,XDH,DIS3L |
| 4.991e-02 | -3.00 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_NKCELL_DN | 188 | 36 | 17758 | 2588 |
GAS2L1,FRMD4A,NLRX1,FBXO2,NES,BLCAP,RSAD1,TNS3,ELMO2,RGS3,PLCG2,PLEKHF1,TUBG1,SCN2A,RAB27B,NCAM1,SYK,TBC1D10B,EPHX1,GCA,MAPKAPK3,ITCH,CR2,UBAC1,PDK3,SOCS3,TXK,SGPP1,RGS9,SERPINA1,H1F0,SECTM1,ARAP1,ARRB1,GRIN2D,IRF7 |
| 4.991e-02 | -3.00 | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP | 188 | 36 | 17758 | 2588 |
PLEKHG3,DCAF7,PDCL,GPR180,FAM78A,ZNF219,MERTK,STIL,EFNB1,COX7A2,ABCD4,TOP2A,OXCT1,PHTF1,CEP78,CD9,TUBG1,SELK,S100A6,PCCB,PTPN18,RHOA,MMD,EIF5A2,WHSC1,TCEAL8,ZDHHC3,DHX32,PAFAH1B3,DHRS13,PRDX3,OTUD6B,PNPLA6,ACADM,CPEB2,ATMIN |
| 4.991e-02 | -3.00 | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDM_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDM_DN | 188 | 36 | 17758 | 2588 |
KIF3C,CCDC109B,HSP90B1,SPC25,NF2,NLRX1,FAM129B,SHPRH,HEXB,GRK6,COX6C,PRKACA,PER2,UHRF1BP1L,ATP6V0B,ADRBK1,ARTN,SNX18,XYLT2,ARL1,SLAIN2,MANF,EGLN3,RNF26,FAR1,SLC35A1,IL1RAP,KDELR1,SMC4,KIF13A,B3GALNT2,ULK2,OTUD6B,NUP37,PTGES,SRSF9 |
| 4.995e-02 | -3.00 | Peroxisome | KEGG pathways | ko04146 | 83 | 19 | 6908 | 1076 |
SOD1,PEX6,AGPS,SOD2,IDH1,NUDT12,MPV17L2,ABCD4,PEX5,PEX2,ECI2,ABCD1,HMGCL,ACSL4,ACOX2,PXMP4,FAR2,FAR1,XDH |
| 4.995e-02 | -3.00 | Peroxisome | KEGG pathways | hsa04146 | 83 | 19 | 6908 | 1076 |
SOD1,PEX6,AGPS,SOD2,IDH1,NUDT12,MPV17L2,ABCD4,PEX5,PEX2,ECI2,ABCD1,HMGCL,ACSL4,ACOX2,PXMP4,FAR2,FAR1,XDH |
| 4.996e-02 | -3.00 | LINDSTEDT_DENDRITIC_CELL_MATURATION_D | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_D | 66 | 15 | 17758 | 2588 |
CD99,SYPL1,QSOX1,NAAA,CDH1,RCBTB2,RAB31,CTNND1,ARHGDIB,ITGAV,RAP1GAP,PTPRE,NAGA,RBMS2,DMPK |
| 4.996e-02 | -3.00 | PID_INTEGRIN1_PATHWAY | MSigDB lists | PID_INTEGRIN1_PATHWAY | 66 | 15 | 17758 | 2588 |
MDK,SPP1,COL6A2,ITGA3,NPNT,ITGA7,PLAUR,ITGA6,COL6A1,COL18A1,COL4A5,COL7A1,IGSF8,ITGAV,CD81 |
| 4.996e-02 | -3.00 | LI_CISPLATIN_RESISTANCE_UP | MSigDB lists | LI_CISPLATIN_RESISTANCE_UP | 24 | 7 | 17758 | 2588 |
UACA,TWIST1,SMARCA2,EGLN3,IGF1R,IRX3,CYP1B1 |
| 4.996e-02 | -3.00 | GNF2_CASP4 | MSigDB lists | GNF2_CASP4 | 24 | 7 | 17758 | 2588 |
SELL,HLA-B,IQGAP1,STAT6,CASP4,CMTM6,RIN3 |
| 4.996e-02 | -3.00 | RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP | MSigDB lists | RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP | 24 | 7 | 17758 | 2588 |
CALM2,CALM3,CTTN,DNPEP,CALM1,CALB2,DHX32 |
| 4.996e-02 | -3.00 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | MSigDB lists | REACTOME_SULFUR_AMINO_ACID_METABOLISM | 24 | 7 | 17758 | 2588 |
GOT1,GCLM,AHCY,APIP,ETHE1,GCLC,CTH |
| 4.996e-02 | -3.00 | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NADH_OR_NADPH | MSigDB lists | OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NADH_OR_NADPH | 24 | 7 | 17758 | 2588 |
GMPR,DHDH,CYB561,NQO1,PRDX3,POR,CYB5R2 |
| 5.000e-02 | -3.00 | AMOTL2 (angiomotin like 2) | protein interactions | 51421 | 71 | 17 | 16036 | 2547 |
MYO5B,AMOTL2,TMCC2,TRAPPC10,NF2,RALBP1,THRA,TRAF2,MPP1,NDC80,MPP5,FXR2,SH3RF2,MAGOHB,SPP1,SP100,LMO4 |